Characterization and performances of DOSION, a dosimetry equipment dedicated to radiobiology experiments taking place at GANIL

NASA Astrophysics Data System (ADS)

Boissonnat, Guillaume; Fontbonne, Jean-Marc; Balanzat, Emmanuel; Boumard, Frederic; Carniol, Benjamin; Cassimi, Amine; Colin, Jean; Cussol, Daniel; Etasse, David; Fontbonne, Cathy; Frelin, Anne-Marie; Hommet, Jean; Salvador, Samuel

2017-06-01

Currently, radiobiology experiments using heavy ions at GANIL (Grand Accélérateur National d‧Ions Lourds) are conducted under the supervision of the CIMAP (Center for research on Ions, MAterials and Photonics). In this context, a new beam monitoring equipment named DOSION has been developed. It allows to perform measurements of accurate fluence and dose maps in near real time for each biological sample irradiated. In this paper, we present the detection system, its design, performances, calibration protocol and measurements performed during radiobiology experiments. This setup is currently available for any radiobiology experiments if one wishes to correlate one's own sample analysis to state-of-the-art dosimetric references.

Characterization of the Medley setup for measurements of neutron-induced fission cross sections at the GANIL-NFS facility

NASA Astrophysics Data System (ADS)

Tarrío, Diego; Prokofiev, Alexander V.; Gustavsson, Cecilia; Jansson, Kaj; Andersson-Sundén, Erik; Al-Adili, Ali; Pomp, Stephan

2017-09-01

Neutron-induced fission cross sections of 235U and 238U are widely used as standards for monitoring of neutron beams and fields. An absolute measurement of these cross sections at an absolute scale, i.e., versus the H(n,p) scattering cross section, is planned with the white neutron beam under construction at the Neutrons For Science (NFS) facility in GANIL. The experimental setup, based on PPACs and ΔE-ΔE-E telescopes containing Silicon and CsI(Tl) detectors, is described. The expected uncertainties are discussed.

Latest results on νμ → ντ oscillations from the OPERA experiment

NASA Astrophysics Data System (ADS)

Komatsu, Masahiro; OPERA Collaboration

2016-04-01

The OPERA experiment is designed to prove neutrino oscillations in the νμ to ντ channel through the direct observation of the tau lepton in tau neutrino charged current interactions. The experiment has accumulated data for five years, from 2008 to 2012, with the CERN Neutrinos to Gran Sasso (CNGS), an almost pure νμ beam. In the last two years, a very large amount of the data accumulated in the nuclear emulsions has been analyzed. The latest results on oscillations with the increased statistics, which include a fourth tau neutrino candidate event, will be presented. Given the extremely low expected background, this result corresponds to the observation of the oscillation process with a four sigma level significance.

Alignment of the CMS Tracker: Latest Results from LHC Run-II

NASA Astrophysics Data System (ADS)

Mittag, Gregor; CMS Collaboration

2017-10-01

The all-silicon design of the tracking system of the CMS experiment provides excellent measurements of charged-particle tracks and an efficient tagging of jets. Conditions of the CMS tracker changed repeatedly during the 2015/2016 shutdown and the 2016 data-taking period. Still the true position and orientation of each of the 15 148 silicon strip and 1440 silicon pixel modules need to be known with high precision for all intervals. The alignment constants also need to be promptly re-adjusted each time the state of the CMS magnet is changed between 0T and 3.8 T. Latest Run-II results of the CMS tracker alignment and resolution performance are presented, which are obtained using several millions of reconstructed tracks from collision and cosmic-ray data of 2016. The geometries and the resulting performance of physics observables are carefully validated. In addition to the offline alignment, an online procedure has been put in place which continuously monitors movements of the pixel high-level structures and triggers updates of the alignment constants if certain thresholds are exceeded.

Perspectives of Super-Heavy Nuclei research with the upcoming separator-spectrometer setup S3 at GANIL/SPIRAL2 - The VAMOS Gas-Filled separator and AGATA

NASA Astrophysics Data System (ADS)

Theisen, Christophe

2017-11-01

Several facilities or apparatus for the synthesis and spectroscopy of the Super-Heavy Nuclei (SHN) are presently under construction in the world, which reflect the large interest for this region of extreme mass and charge, but also for the need of even more advanced research infrastructures. Among this new generation, the GANIL/SPIRAL2 facility in Caen, France, will soon deliver very high intense ion beams of several tens of particle μA. The Super Separator Spectrometer S3 has been designed to exploit these new beams for the study of SHN after separation. It will provide the needed beam rejection, mass selection and full arsenal of state-of-the art detection setups. Still at GANIL, the AGATA new generation gamma-ray tracking array is being operated. The VAMOS high acceptance spectrometer is being upgraded as a gas-filled separator. Its coupling with AGATA will lower the spectroscopic limits for the prompt gamma-ray studies of heavy and super-heavy nuclei. In this proceeding, these new devices will be presented along with a selected physics case.

ESA to present the latest Venus Express results to the media

NASA Astrophysics Data System (ADS)

2007-11-01

The launch of Venus Express back in November 2005 represented a major milestone in the exploration of Venus — a planet unvisited by any dedicated spacecraft since the early 1990s. One of the fundamental questions being addressed by the Venus Express mission is why a world so similar to Earth in mass and size has evolved so differently, to become the noxious and inhospitable planet it is today. Since it started its scientific observations in July 2006, Venus Express has been making the most detailed study of the planet’s thick and complex atmosphere to date. The latest findings not only highlight the features that make Venus unique in the solar system but also provide fresh clues as to how the planet is — despite everything — a more Earth-like planetary neighbour than one could have imagined. The results will appear in a special section of the 29 November issue of the journal Nature containing nine individual papers devoted to Venus Express science activities. Media organisations interested in attending the press conference are invited to register via the form attached below. Media that cannot attend will have the opportunity to follow the press conference via the following phone line: +33 1 58 99 57 42 (listening-mode only).The results presented at the press conference are embargoed until 28 November 19:00 CET. For more information ESA Media Relations Office Tel: +33 1 5369 7299 Fax: +33 1 5369 7690 Media event programme ‘Venus: a more Earth-like planetary neighbour’ Latest results from Venus Express 28 November 2007, 15:00, room 137 ESA Headquarters, 8-10 rue Mario-Nikis, Paris 15:00 Introduction, by Håkan Svedhem, ESA Venus Express Project Scientist 15:07 Venus: What we knew before, by Fred Taylor, Venus Express Interdisciplinary Scientist 15:15 Temperatures in the atmosphere of Venus, by Jean-Loup Bertaux, SPICAV Principal Investigator 15:25 The dynamic atmosphere of Venus, by Giuseppe Piccioni, VIRTIS Principal Investigator 15:40 Venus�

The FOXSI sounding rocket: Latest analysis and results

NASA Astrophysics Data System (ADS)

Buitrago-Casas, Juan Camilo; Glesener, Lindsay; Christe, Steven; Krucker, Sam; Ishikawa, Shin-Nosuke; Takahashi, Tadayuki; Ramsey, Brian; Han, Raymond

2016-05-01

Hard X-ray (HXR) observations are a linchpin for studying particle acceleration and hot thermal plasma emission in the solar corona. Current and past indirectly imaging instruments lack the sensitivity and dynamic range needed to observe faint HXR signatures, especially in the presences of brighter sources. These limitations are overcome by using HXR direct focusing optics coupled with semiconductor detectors. The Focusing Optics X-ray Solar Imager (FOXSI) sounding rocket experiment is a state of the art solar telescope that develops and applies these capabilities.The FOXSI sounding rocket has successfully flown twice, observing active regions, microflares, and areas of the quiet-Sun. Thanks to its far superior imaging dynamic range, FOXSI performs cleaner hard X-ray imaging spectroscopy than previous instruments that use indirect imaging methods like RHESSI.We present a description of the FOXSI rocket payload, paying attention to the optics and semiconductor detectors calibrations, as well as the upgrades made for the second flight. We also introduce some of the latest FOXSI data analysis, including imaging spectroscopy of microflares and active regions observed during the two flights, and the differential emission measure distribution of the nonflaring corona.

Nuclear data measurements at the new NFS facility at GANIL

NASA Astrophysics Data System (ADS)

Gustavsson, C.; Pomp, S.; Scian, G.; Lecolley, F.-R.; Tippawan, U.; Watanabe, Y.

2012-10-01

The NFS (Neutrons For Science) facility is part of the SPRIAL 2 project at GANIL, Caen, France. The facility is currently under construction and the first beam is expected in early 2013. NFS will have a white neutron source covering the 1-40 MeV energy range with a neutron flux higher than comparable facilities. A quasi-mono-energetic neutron beam will also be available. In these energy ranges, especially above 14 MeV, there is a large demand for neutron-induced data for a wide range of applications involving dosimetry, medical therapy, single-event upsets in electronics and nuclear energy. Today, there are a few or no cross section data on reactions such as (n, fission), (n, xn), (n, p), (n, d) and (n, α). We propose to install experimental equipment for measuring neutron-induced light-charged particle production and fission relative to the H(n, p) cross section. Both the H(n, p) cross section and the fission cross section for 238U are important reference cross sections used as standards for many other experiments. Nuclear data for certain key elements, such as closed shell nuclei, are also of relevance for the development of nuclear reaction models. Our primary intention is to measure charged particle production (protons, deuterons and alphas) from 12C, 16O, 28Si and 56Fe and neutron-induced fission cross sections from 238U and 232Th.

Latest Results from the Multi-Object Keck Exoplanet Tracker

NASA Astrophysics Data System (ADS)

Van Eyken, Julian C.; Ge, J.; Wan, X.; Zhao, B.; Hariharan, A.; Mahadevan, S.; DeWitt, C.; Guo, P.; Cohen, R.; Fleming, S. W.; Crepp, J.; Warner, C.; Kane, S.; Leger, F.; Pan, K.

2006-12-01

The W. M. Keck Exoplanet Tracker is a precision Doppler radial velocity instrument based on dispersed fixed-delay interferometry (DFDI) which takes advantage of the new technique to allow multi-object RV surveying. Installed at the 2.5m Sloan telescope at Apache Point Observatory, the combination of Michelson interferometer and medium resolution spectrograph allows design for simultaneous Doppler measurements of up to 60 targets, while maintaining high instrument throughput. Using a single-object prototype of the instrument at the Kitt Peak National Observatory 2.1m telescope, we previously discovered a 0.49MJup planet, HD 102195b (ET-1), orbiting with a 4.11d period, and other interesting targets are being followed up. From recent trial observations, the Keck Exoplanet Tracker now yields 59 usable simultaneous fringing stellar spectra, of a quality sufficient to attempt to detect short period hot-Jupiter type planets. Recent engineering improvements reduced errors by a factor of 2, and typical photon limits for stellar data are now at the 30m/s level for magnitude V 10.5 (depending on spectral type and v sin i), with a best value of 6.9m/s at V=7.6. Preliminary RMS precisions from solar data (daytime sky) are around 10m/s over a few days, with some spectra reaching close to their photon limit of 6-7m/s on the short term ( 1 hour). A number of targets showing interesting RV variability are currently being followed up independently. Additional engineering work is planned which should make for further significant gains in Doppler precision. Here we present the latest results and updates from the most recent engineering and observing runs with the Keck ET.

Latest Results From the QuakeFinder Statistical Analysis Framework

NASA Astrophysics Data System (ADS)

Kappler, K. N.; MacLean, L. S.; Schneider, D.; Bleier, T.

2017-12-01

be analysed using the Receiver Operating Characteristic test. In this presentation we give a status report of our latest results, largely focussed on reproducibility of results, robust statistics in the presence of missing data, and exploring optimization landscapes in our parameter space.

Latest Surprises from Mira the Wonderful

NASA Astrophysics Data System (ADS)

Karovska, Margarita; Marengo, Massimo; Wood, Brian

We report the latest results from our long-term study of Mira A and its companion Mira B. These include a study of the dust environment in mid-IR wavelengths (Marengo et al. 2001), and of the accretion processes in the Mira AB interacting system (Wood, Karovska, and Raymond 2002).

The Latest Forecast.

ERIC Educational Resources Information Center

Laurence, David

2002-01-01

Discusses the "latest forecast" for the future of English departments. Addresses departmental and institutional staffing practices, employment opportunities for PhDs, the acceleration of change in the institution, and the general state of the study and teaching of English. (RS)

Glaucoma: Symptoms, Diagnosis, Treatment and Latest Research

MedlinePlus

... Feature: Glaucoma Glaucoma: Symptoms, Diagnosis, Treatment and Latest Research Past Issues / Fall 2009 Table of Contents Symptoms ... patients may need to keep taking drugs. Latest Research Researchers are studying the causes of glaucoma, looking ...

SPIRAL2 at GANIL: Status and Perspectives

NASA Astrophysics Data System (ADS)

Gales, S.

2008-05-01

To pursue the investigation of a new territory of nuclei with extreme N/Z called ``terra incognita'' several projects, all aiming at the increase by several orders of magnitude of the RIB intensities are now under discussions worldwide. In Europe, two major new projects have been approved recently FAIRatGSI using the so-called ``in-flight'' method and SPIRAL2atGANIL, based on the ISOL method. Both projects were selected in the European Strategic Roadmap For research Infrastructures (ESFRI). The main goal of SPIRAL2 is clearly to extend our knowledge of the limit of existence and the structure of nuclei deeply in the medium and heavy mass region (A = 60 to 140) which is to day an almost unexplored continent. SPIRAL 2 is based on a high power, CW, superconducting driver LINAC, delivering 5 mA of deuteron beams at 40 MeV (200 KW) directed on a C converter+ Uranium target and producing therefore more 1013 fissions/s. The expected radioactive beams intensities for exotic species in the mass range from A = 60 to A = 140, of the order of 106 to 1010 pps will surpass by two order of magnitude any existing facilities in the world. These unstable atoms will be available at energies between few KeV/n to 15 MeV/n. The same driver will accelerate high intensity (100 μA to 1 mA), heavier ions up to Ar at 14 MeV/n producing also proton rich exotic nuclei. In applied areas SPIRAL2 is considered as a powerful variable energy neutron source, a must to study the impact of nuclear fission and fusion on materials. The intensities of these unstable species are excellent opportunities for new tracers and diagnostics either for solid state, material or for radiobiological science and medicine. The ``Go'' decision has been taken in May 2005. The investments and personnel costs amount to 190 M€, for the construction period 2006-2012. Construction of the SPIRAL2 facility is shared by ten French laboratories and a network of international partners. Under the 7FP program of European Union

Latest Advances in Antibacterial Materials

NASA Astrophysics Data System (ADS)

Loh, Xian Jun

This paper will update readers on the latest work in the area of antibacterial polymeric systems. There is extensive literature on existing systems. This complexity confines us to the latest antibacterial materials which possess (1) responsive antibacterial activity on their own; (2) anti-biofilm formation and (3) formation of antibacterial polymeric films. The objective of this review is to provide an overview of the antibacterial synthetic polymer field. In this paper, I will analyze the early promise of this technology as well as highlight potential challenges that adopters could face. The primary focus will be the application of materials to the medical industry and to show how these materials can be tailored to create responsive, customized bactericidal materials.

Latest technologies on ultrasonic cleaning

NASA Astrophysics Data System (ADS)

Hofstetter, Hans U.

2007-05-01

UCM-AG manufactures Ultrasonic Cleaning Machines for highest quality requirements. The company has the know-how for cleaning and supplies cleaning systems together with the cleaning process. With a UCM of Switzerland Cleaning System, the customer gets the system itself, the cleaning process with a guarantee for the specified result but also all auxiliary equipment needed for perfect results. Therefore UCM also supplies fixtures, linkage to existing automated fabrication facilities water treatment plants etc. Thus the UCM customer gets a turnkey installation - ready to operate and including know-how. UCM of Switzerland will describe the latest technology in ultrasonic precision cleaning on the example of a recent and sophisticated installation. The installation consists of three interlinked cleaning systems which operate completely automated. The 1st system is designed for pre-cleaning to remove waxes, pitch and protection lacquers with environmentally friendly solvents which are non hazardous to the health of the operators. The 2nd system cleans the parts prior to inspection and operates with neutral or slightly alkaline detergents. The 3rd system is designed for final cleaning prior to vacuum coating and perfect results are required. It combines cleaning tanks and DI-Water rinse with lift out and vacuum dryer. The installation combines the latest technologies in ultrasonic cleaning for precision optical components. The system employs multi frequency immersed ultrasonic transducers and special rinsing technologies The complete installation will be explained in detail; the concept in its whole, the lay out, the particular setup of each cleaning system etc. will be shown and explained together with construction particulars of the complete installation.

Latest results of OPERA

NASA Astrophysics Data System (ADS)

Meregaglia, A.; Opera Collaboration

2017-04-01

OPERA is a long baseline neutrino experiment which took data between 2008 and 2012 having for goal the observation of the νμ →ντ transition in appearance mode i.e. detecting the τ lepton. The detector was located in the underground Gran Sasso laboratory, 730 km away from the CNGS neutrino beam production at CERN. The collaboration observed 5 ντ candidates which, considering the very low expected background of 0.25 events, allowed for a discovery claim of neutrino oscillation in appearance mode at the level of 5.1 σ. Additional analyses were performed aiming at the possible observation of the νμ →νe transition, and at the search for anomalies related to the possible existence of a sterile neutrino. In this paper, after a short introduction describing the detector, the different results are presented on both oscillation channels including standard 3 flavour scenario and possible new physics.

Artificial sensory organs: latest progress.

PubMed

Nakamura, Tatsuo; Inada, Yuji; Shigeno, Keiji

2018-03-01

This study introduces the latest progress on the study of artificial sensory organs, with a special emphasis on the clinical results of artificial nerves and the concept of in situ tissue engineering. Peripheral nerves have a strong potential for regeneration. An artificial nerve uses this potential to recover a damaged peripheral nerve. The polyglycolic acid collagen tube (PGA-C tube) is a bio-absorbable tube stuffed with collagen of multi-chamber structure that consists of thin collagen films. The clinical application of the PGA-C tube began in 2002 in Japan. The number of PGA-C tubes used is now beyond 300, and satisfactory results have been reported on peripheral nerve repairs. This PGA-C tube is also effective for patients suffering from neuropathic pain.

Editorial: Latest methods and advances in biotechnology.

PubMed

Lee, Sang Yup; Jungbauer, Alois

2014-01-01

The latest "Biotech Methods and Advances" special issue of Biotechnology Journal continues the BTJ tradition of featuring the latest breakthroughs in biotechnology. The special issue is edited by our Editors-in-Chief, Prof. Sang Yup Lee and Prof. Alois Jungbauer and covers a wide array of topics in biotechnology, including the perennial favorite workhorses of the biotech industry, Chinese hamster ovary (CHO) cell and Escherichia coli. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Hot Dry Rock Induced Seismicity - Latest results from Basel, Switzerland

NASA Astrophysics Data System (ADS)

Deichmann, N.; Kraft, T.; Husen, S.

2009-12-01

The Deep Heat Mining project in Basel, Switzerland, was one of the first purely commercially oriented Enhanced Geothermal System (EGS) projects. Beginning on 2 December 2006, water was injected into a 5 km deep well with increasing flow rates. Because of strongly increased seismic activity, which included a ML2.7 event, injection had already been stopped a few hours prior to a ML3.4 event that occurred on 8 December 2006. This earthquake rattled the local population and received international media attention. Slight nonstructural damage has been claimed by many homeowners, with a damage sum of US$7 million. Bleed-off of the injection well was initiated about 1 hour after the ML3.4 event, and hydrostatic down-hole pressure was reached within 4 days. Since then, the seismicity slowly decayed. Three additional earthquakes with ML > 3 were felt 1-2 months after bleed-off. More than 2 years later, sporadic seismicity inside the stimulated rock volume is still being detected by the down-hole instruments. At present, the EGS project is on hold and awaits the completion of an independent risk analysis study. Here, we report on latest results of the analysis of the induced earthquake sequence which is one of the most densely monitored deep fluid-injections in the world. The seismic monitoring system consisted of six borehole seismometers near the injection well and of up to 30 seismic surface stations in the Basel area. The network is to a large part operational until today. Considerable improvement of the hypocenter locations was achieved by refinement of arrival-time picks and subsequent relocation. First, highly similar events where grouped by a cluster analysis based on broad-banded waveform cross-correlation. In a second step, we improve the P and S arrival-time picks in a semi-automatic procedure by taking advantage of the waveform similarity within the clusters and the improvement of the signal-to-noise ratio by stacking. Finally, we relocate the strongest event of

The Titan Haze Simulation Experiment: Latest Laboratory Results and Dedicated Plasma Chemistry Model

NASA Astrophysics Data System (ADS)

Sciamma-O'Brien, Ella; Raymond, Alexander; Mazur, Eric; Salama, Farid

2017-06-01

In Titan’s atmosphere, a complex organic chemistry occurs between its main constituents, N2 and CH4, and leads to the production of larger molecules and solid aerosols.Here, we present the latest results on the gas and solid phase analyses in the Titan Haze Simulation (THS) experiment, developed on the NASA Ames COSmIC simulation chamber. The THS is a unique experimental platform that allows us to simulate Titan’s atmospheric chemistry at Titan-like temperature (200K) by cooling down N2-CH4-based mixtures in a supersonic expansion before inducing the chemistry by plasma. Because of the accelerated gas flow in the expansion, the residence time of the gas in the active plasma region is less than 3 µs. This results in a truncated chemistry that enables us to monitor the first and intermediate steps of the chemistry as well as specific chemical pathways when adding, in the initial gas mixture, heavier molecules that have been detected as trace elements on Titan[1].We discuss the results of recent Mid-infrared (MIR) spectroscopy[2] and X-ray Absorption Near Edge Structure spectroscopy studies of THS Titan tholins produced in different gas mixtures (with and without acetylene and benzene). Both studies have shown the presence of nitrogen chemistry, and differences in the level and nature of the nitrogen incorporation depending on the initial gas mixture. A comparison of THS MIR spectra to VIMS data has shown that the THS aerosols produced in simpler mixtures, i.e., that contain more nitrogen and where the N-incorporation is in isocyanide-type molecules instead of nitriles, are more representative of Titan’s aerosols.In addition, a new model has been developed to simulate the plasma chemistry in the THS. Electron impact and chemical kinetics equations for more than 120 species are followed. The calculated mass spectra are in good agreement with the experimental THS mass spectra[1], confirming that the short residence time in the plasma cavity limits the growth of

The Titan Haze Simulation Experiment: Latest Laboratory Results and Dedicated Plasma Chemistry Model

NASA Astrophysics Data System (ADS)

Sciamma-O'Brien, Ella; Raymond, Alexander; Mazur, Eric; Salama, Farid

2017-10-01

Here, we present the latest results on the gas- and solid phase analyses in the Titan Haze Simulation (THS) experiment, developed at the NASA Ames COSmIC simulation chamber. The THS is a unique experimental platform that allows us to simulate Titan’s complex atmospheric chemistry at Titan-like temperature (200 K) by cooling down N2-CH4-based mixtures in a supersonic expansion before inducing the chemistry by plasma. Because of the accelerated gas flow in the expansion, the residence time of the gas in the active plasma region is less than 3 µs. This results in a truncated chemistry that enables us to control how far in the chain of chemical reactions chemistry processes[1], by adding, in the initial gas mixture, heavier molecules that have been detected as trace elements on Titan.We discuss the results of recent Mid-infrared (MIR) spectroscopy[2] and X-ray Absorption Near Edge Structure spectroscopy studies of THS Titan tholins produced in different gas mixtures (with and without acetylene and benzene). Both studies have shown the presence of nitrogen chemistry, and differences in the level and nature of the nitrogen incorporation depending on the initial gas mixture. A comparison of THS MIR spectra to VIMS data has shown that the THS aerosols produced in simpler mixtures, i.e., that contain more nitrogen and where the N-incorporation is in isocyanide-type molecules instead of nitriles, are more representative of Titan’s aerosols.In addition, a new model has been developed to simulate the plasma chemistry in the THS. Electron impact and chemical kinetics equations for more than 120 species are followed. The calculated mass spectra[3] are in good agreement with the experimental THS mass spectra[1], confirming that the short residence time in the plasma cavity limits the growth of larger species and results in a truncated chemistry, a main feature of the THS.References:[1] Sciamma-O'Brien E. et al., Icarus, 243, 325 (2014)[2] Sciamma-O'Brien E. et al., Icarus

Latest Cretaceous-Paleogene basin development and resultant sedimentation patterns in the thrust belt and broken foreland of central Utah

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lawton, T.F.; Franczyk, K.J.; Pitman, J.K.

1990-05-01

Latest Cretaceous tectonism in central and east-central Utah formed several intermontane basins both atop thrust sheets and between the thrust front and basement-involved uplifts in the former foreland basin. The upper Campanian Castlegate Sandstone and its inferred western equivalents were the last strata deposited prior to segmentation of the foreland basin. Thereafter, eastward transport of the thrust allochthon uplifted the most proximal part of the Castlegate depositional wedge. West of the thrust front, small intermontane basins formed on the allochthon. Sediment was transported into these basins from both eastern and western sources. In each basin, facies grade from basin-margin conglomeraticmore » alluvial fan deposits to basin-interior flood-plain and lacustrine deposits within a few kilometers. These intermontane basins existed from latest Campanian through the late Paleocene, and may have been transported a short distance eastward as they formed. East of the thrust front in the latest Campanian and contemporaneous with basin formation on the allochthon, a northward-northeastward-flowing big river system transported sediment into the foreland basin from feldspar-rich source areas southwest of the study area. Subsequently, major movement of the San Rafael uplift in the very late Campanian or early Maastrichtian gave rise to an intermontane basin between the thrust front and the San Rafael uplift. Northwestward-flowing, pebble-bearing braided rivers deposited the oldest sediments in this basin prior to an influx from the south and southwest of sediment that formed a thick Maastrichtian clastic sequence. In contrast to deposition in basins on the allochthon, deposition east of the thrust front in the Paleocene was intermittent and restricted to rapidly shifting centers of basin subsidence.« less

Cometary dust at the smallest scale - latest results of the MIDAS Atomic Force Microscope onboard Rosetta

NASA Astrophysics Data System (ADS)

Bentley, Mark; Torkar, Klaus; Jeszenszky, Harald; Romstedt, Jens; Schmied, Roland; Mannel, Thurid

2015-04-01

The MIDAS instrument onboard the Rosetta orbit is a unique combination of a dust collection and handling system and a high resolution Atomic Force Microscope (AFM). By building three-dimensional images of the dust particle topography, MIDAS addresses a range of fundamental questions in Solar System and cometary science. The first few months of dust collection and scanning revealed a deficit of smaller (micron and below) particles but eventually several 10 µm-class grains were discovered. In fact these were unexpectedly large and close to the limit of what is observable with MIDAS. As a result the sharp tip used by the AFM struck the particles from the side, causing particle breakage and distortion. Analyses so far suggest that the collected particles are fluffy aggregates of smaller sub-units, although determination of the size of these sub-units and high resolution re-imaging remains to be done. The latest findings will be presented here, including a description of the particles collected and the implications of these observations for cometary science and the Rosetta mission at comet 67P.

MOVES2014a: Latest Version of MOtor Vehicle Emission Simulator (MOVES)

EPA Pesticide Factsheets

MOVES2014a is the latest version of MOVES. It incorporates significant improvements in calculating onroad and nonroad equipment emissions. MOVES2014a does not significantly change the criteria pollutant emissions results of MOVES2014.

Latest results from Daya Bay

NASA Astrophysics Data System (ADS)

Vorobel, Vit; Daya Bay Collaboration

2017-07-01

The Daya Bay Reactor Neutrino Experiment was designed to measure θ 13, the smallest mixing angle in the three-neutrino mixing framework, with unprecedented precision. The experiment consists of eight functionally identical detectors placed underground at different baselines from three pairs of nuclear reactors in South China. Since Dec. 2011, the experiment has been running stably for more than 4 years, and has collected the largest reactor anti-neutrino sample to date. Daya Bay is able to greatly improve the precision on θ 13 and to make an independent measurement of the effective mass splitting in the electron antineutrino disappearance channel. Daya Bay can also perform a number of other precise measurements, such as a high-statistics determination of the absolute reactor antineutrino flux and spectrum, as well as a search for sterile neutrino mixing, among others. The most recent results from Daya Bay are discussed in this paper, as well as the current status and future prospects of the experiment.

Latest developments in the Advanced Photovoltaic Solar Array Program

NASA Technical Reports Server (NTRS)

Stella, Paul M.; Kurland, Richard M.

1990-01-01

In 1985, the Advanced Photovoltaic Solar Array (APSA) Program was established to demonstrate a producible array system with a specific power greater than 130 W/kg at a 10-kW (BOL) power level. The latest program phase completed fabrication and initial functional testing of a prototype wing representative of a full-scale 5-kW (BOL) wing (except truncated in length to about 1 kW), with weight characteristics that could meet the 130-W/kg (BOL) specific power goal using thin silicon solar cell modules and weight-efficient structural components. The wing configuration and key design details are reviewed, along with results from key component-level and wing-level tests. Projections for future enhancements that may be expected through the use of advanced solar cells and structural components are shown. Performance estimates are given for solar electric propulsion orbital transfer missions through the Van Allen radiation belts. The latest APSA program plans are presented.

The Latest Scams in Literacy Education.

ERIC Educational Resources Information Center

Berger, Alan

The claims for the huge numbers of students suffering from the "latest scams" in literacy education--learning disability, dyslexia, attention deficit disorder, at risk, and hypoglycemia--are driven by political, economic, and social profits with minimal concern for children. While such problems exist, the phrases used to describe these…

The Titan Haze Simulation Experiment: Latest Laboratory Results and Dedicated Plasma Chemistry Model

NASA Astrophysics Data System (ADS)

Sciamma-O'Brien, Ella; Raymond, Alexander; Mazur, Eric; Salama, Farid

2018-06-01

Here, we present the latest results on the gas and solid phase analyses in the Titan Haze Simulation (THS) experiment. The THS experiment, developed at NASA Ames’ COSmIC facility is a unique experimental platform that allows us to simulate Titan’s complex atmospheric chemistry at Titan-like temperature (200 K) by cooling down N2-CH4-based mixtures in a supersonic expansion before inducing the chemistry by plasma.Gas phase: The residence time of the jet-accelerated gas in the active plasma region is less than 4 µs, which results in a truncated chemistry enabling us to control how far in the chain of reactions the chemistry is processing. By adding heavier molecules in the initial gas mixture, it is then possible to study the first and intermediate steps of Titan’s atmospheric chemistry as well as specific chemical pathways, as demonstrated by mass spectrometry and comparison to Cassini CAPS data [1]. A new model was recently developed to simulate the plasma chemistry in the THS. Calculated mass spectra produced by this model are in good agreement with the experimental THS mass spectra, confirming that the short residence time in the plasma cavity limits the growth of larger species [2].Solid phase: Scanning electron microscopy and infrared spectroscopy have been used to investigate the effect of the initial gas mixture on the morphology of the THS Titan aerosol analogs as well as on the level and nature of the nitrogen incorporation into these aerosols. A comparison to Cassini VIMS observational data has shown that the THS aerosols produced in simpler mixtures, i.e., that contain more nitrogen and where the N-incorporation is in isocyanide-type molecules instead of nitriles, are more representative of Titan’s aerosols [3]. In addition, a new optical constant facility has been developed at NASA Ames that allows us to determine the complex refractive indices of THS Titan aerosol analogs from NIR to FIR (0.76-222 cm-1). The facility and preliminary results

Latest Proterozoic stratigraphy and Earth history.

PubMed

Knoll, A H; Walter, M R

1992-04-23

The end of the Proterozoic Eon was a time of pronounced biological, biogeochemical, climatic and tectonic change. New bio- and chemostratigraphic data provide an improved framework for stratigraphic correlation, making possible a deeper understanding of latest Proterozoic Earth history and providing tools for a chronostratigraphic division of late Proterozoic time.

Latest result of PRK with excimer laser

NASA Astrophysics Data System (ADS)

Okamoto, Shinseiro; Okamoto, Michika

1996-05-01

We have in the last two years, performed PRK operation on over 300 human myopic eyes using ArF excimer laser with a Summit 'Omnimed' machine. For the initial 53 myopic eyes we treated, results were very good for those with correction less than minus 6 diopters. However, as previously reported, we also witnessed some regression for those eyes exceeding correction of more than minus 6 diopters. To counter such ill results of PRK we devised and suggested many new procedures for PRK with very good results. One such invention is the 'Okamoto-type' cooling machine for the cornea which reduces and stabilizes cornea temperature at 0 degrees Celsius while simultaneously bathing the cornea with special cooling fluid. After the operation, EGF, fibronectin and hexapeptide were administered using eyedrops. Soft contact lenses were used to protect the cornea, improve delivery of medication to the operated area, prevent infection and inflammation and also promote uniform and faster ephiterium regrowth. We were able to document very good post-operative results using this method, thereby giving us strong assurance that we have reached a significant milestone in PRK operation. Our report today covers post operative results of the 52 eyes we operated on and tracked for more than one year.

Latest Developments and Future Perspectives in the Field Of Obesity.

PubMed

Pérez-Pevida, Belén; Miras, Alexander D

2017-04-01

The prevalence of obesity is increasing exponentially worldwide, becoming an international public health issue that affects quality of life, increases the risk of illness and raises healthcare costs in countries in all parts of the world. In this editorial, we analyse the latest progress in the management of obesity and associated cardiovascular risk factors, and summarise the latest randomised controlled trials that have had the biggest influence on the current changes we are experiencing in obesity management.

Latest Cretaceous climatic and environmental change in the South Atlantic region

NASA Astrophysics Data System (ADS)

Woelders, L.; Vellekoop, J.; Kroon, D.; Smit, J.; Casadío, S.; Prámparo, M. B.; Dinarès-Turell, J.; Peterse, F.; Sluijs, A.; Lenaerts, J. T. M.; Speijer, R. P.

2017-05-01

Latest Maastrichtian climate change caused by Deccan volcanism has been invoked as a cause of mass extinction at the Cretaceous-Paleogene (K-Pg) boundary ( 66.0 Ma). Yet late Maastrichtian climate and ecological changes are poorly documented, in particular on the Southern Hemisphere. Here we present upper Maastrichtian-lower Danian climate and biotic records from the Bajada del Jagüel (BJ) shelf site (Neuquén Basin, Argentina), employing the TEX86 paleothermometer, marine palynology (dinoflagellate cysts), and micropaleontology (foraminifera). These records are correlated to the astronomically tuned Ocean Drilling Program Site 1262 (Walvis Ridge). Collectively, we use these records to assess climatic and ecological effects of Deccan volcanism in the Southern Atlantic region. Both the TEX86-based sea surface temperature (SST) record at BJ and the bulk carbonate δ18O-based SST record of Site 1262 show a latest Maastrichtian warming of 2.5-4°C, at 450 to 150 kyr before the K-Pg boundary, coinciding with the a large Deccan outpouring phase. Benthic foraminiferal and dinocyst assemblage changes indicate that this warming resulted in enhanced runoff and stratification of the water column, likely resulting from more humid climate conditions in the Neuquén Basin. These climate conditions could have been caused by an expanding and strengthening thermal low over the South American continent. Biotic changes in response to late Maastrichtian environmental changes are rather limited, when compared to the major turnovers observed at many K-Pg boundary sites worldwide. This suggests that environmental perturbations during the latest Maastrichtian warming event were less severe than those following the K-Pg boundary impact.

Latest Cretaceous Climatic and Environmental Change in the South Atlantic Region

NASA Astrophysics Data System (ADS)

Woelders, L.; Vellekoop, J.; Smit, J.; Kroon, D.; Casadío, S.; Prámparo, M.; Dinarès-turell, J.; Peterse, F.; Sluijs, A.; Speijer, R. P.

2016-12-01

It is generally assumed that the Chicxulub impact resulted in the Cretaceous-Paleogene (K-Pg) boundary mass extinction ( 66 Ma). However, there is continuing debate about the contribution of latest Maastrichtian climate changes, possibly caused by Deccan volcanism, to this mass extinction event. This debate is complicated because of the lack of high quality latest Maastrichtian climatological and ecological reconstructions. Here we present an astronomically tuned late Maastrichtian - early Danian record of bulk carbonate δ18O, a proxy record of sea surface temperature (SST), from Southern Atlantic Ocean Drilling Program Site 1262 (Walvis Ridge) and a late Maastrichtian TEX86 sea surface temperature record from the Bajada del Jagüel site in the Neuquén Basin (Argentina). The combination of these inferred temperature records with foraminiferal and organic-walled dinoflagellate cyst (dinocyst) data from Bajada del Jagüel allows to reconstruct environmental changes across this time interval in a mid-latitude, Southern Atlantic setting. Our results show that latest Maastrichtian warming of 2.5-4°C started gradually around 66.7 Ma, culminating in the interval between 450 to 150 kyr before the K-Pg boundary. Highest temperatures occurred 200 kyr before the K-Pg boundary. During the last 150 kyr of the Maastrichtian, the temperature trend reversed again at both sites. Benthic foraminiferal and dinocyst assemblage changes indicate that late Maastrichtian warming resulted in more humid climate conditions in the Neuquén basin, causing enhanced runoff and stratification of the water column. Vice versa, the subsequent cooling induced again a drier climate in the basin, resulting in reduced salinity stratification and better ventilation of the basin. We conclude that late Maastrichtian climate and sea level change caused distinct environmental perturbations in the Neuquén basin, although it remains uncertain to which extent late Maastrichtian climatological changes

Israel's Latest Conflict: Paying for Higher Education

ERIC Educational Resources Information Center

Kalman, Matthew

2007-01-01

This article describes Israel's latest conflict--plummeting government spending and strikes by faculty members and students which are threatening the stability of the country's universities. The founders of the modern state of Israel considered higher education to be so important that they established the country's first two universities long…

Latest NIH Research | NIH MedlinePlus the Magazine

MedlinePlus

... this page please turn Javascript on. Feature: Quit Smoking Latest NIH Research Past Issues / Winter 2011 Table ... with chest X-rays. Clinical Trials Related to Smoking Clinical trials are scientific studies that try to ...

ATRF Houses the Latest DNA Sequencing Technologies | Poster

Cancer.gov

By Ashley DeVine, Staff Writer By the end of October, the Advanced Technology Research Facility (ATRF) will be one of the few facilities in the world to house all of the latest DNA sequencing technologies.

Latest Proterozoic stratigraphy and earth history

NASA Technical Reports Server (NTRS)

Knoll, Andrew H.; Walter, Malcolm R.

1992-01-01

Novel biostratigraphic and chemostratigraphic data furnish an improved framework for stratigraphic correlation of the Proterozoic Eon as well as tools for a chronostratigraphic division of the late Proterozoic. It is argued that, in conjunction with geochronometric data, protistan microfossils and isotope geochemistry can furnish a means for an eventual integration of the latest Proterozoic Eon. Attention is given to the emerging methodologies of fossil protists and prokaryotes and of isotopic chemostratigraphy.

Lactate Chemical Exchange Saturation Transfer (LATEST) Imaging in vivo A Biomarker for LDH Activity.

PubMed

DeBrosse, Catherine; Nanga, Ravi Prakash Reddy; Bagga, Puneet; Nath, Kavindra; Haris, Mohammad; Marincola, Francesco; Schnall, Mitchell D; Hariharan, Hari; Reddy, Ravinder

2016-01-22

Non-invasive imaging of lactate is of enormous significance in cancer and metabolic disorders where glycolysis dominates. Here, for the first time, we describe a chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) method (LATEST), based on the exchange between lactate hydroxyl proton and bulk water protons to image lactate with high spatial resolution. We demonstrate the feasibility of imaging lactate with LATEST in lactate phantoms under physiological conditions, in a mouse model of lymphoma tumors, and in skeletal muscle of healthy human subjects pre- and post-exercise. The method is validated by measuring LATEST changes in lymphoma tumors pre- and post-infusion of pyruvate and correlating them with lactate determined from multiple quantum filtered proton magnetic resonance spectroscopy (SEL-MQC (1)H-MRS). Similarly, dynamic LATEST changes in exercising human skeletal muscle are correlated with lactate determined from SEL-MQC (1)H-MRS. The LATEST method does not involve injection of radioactive isotopes or labeled metabolites. It has over two orders of magnitude higher sensitivity compared to conventional (1)H-MRS. It is anticipated that this technique will have a wide range of applications including diagnosis and evaluation of therapeutic response of cancer, diabetes, cardiac, and musculoskeletal diseases. The advantages of LATEST over existing methods and its potential challenges are discussed.

Lactate Chemical Exchange Saturation Transfer (LATEST) Imaging in vivo A Biomarker for LDH Activity

PubMed Central

DeBrosse, Catherine; Nanga, Ravi Prakash Reddy; Bagga, Puneet; Nath, Kavindra; Haris, Mohammad; Marincola, Francesco; Schnall, Mitchell D.; Hariharan, Hari; Reddy, Ravinder

2016-01-01

Non-invasive imaging of lactate is of enormous significance in cancer and metabolic disorders where glycolysis dominates. Here, for the first time, we describe a chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) method (LATEST), based on the exchange between lactate hydroxyl proton and bulk water protons to image lactate with high spatial resolution. We demonstrate the feasibility of imaging lactate with LATEST in lactate phantoms under physiological conditions, in a mouse model of lymphoma tumors, and in skeletal muscle of healthy human subjects pre- and post-exercise. The method is validated by measuring LATEST changes in lymphoma tumors pre- and post-infusion of pyruvate and correlating them with lactate determined from multiple quantum filtered proton magnetic resonance spectroscopy (SEL-MQC 1H-MRS). Similarly, dynamic LATEST changes in exercising human skeletal muscle are correlated with lactate determined from SEL-MQC 1H-MRS. The LATEST method does not involve injection of radioactive isotopes or labeled metabolites. It has over two orders of magnitude higher sensitivity compared to conventional 1H-MRS. It is anticipated that this technique will have a wide range of applications including diagnosis and evaluation of therapeutic response of cancer, diabetes, cardiac, and musculoskeletal diseases. The advantages of LATEST over existing methods and its potential challenges are discussed. PMID:26794265

The last polar dinosaurs: high diversity of latest Cretaceous arctic dinosaurs in Russia

NASA Astrophysics Data System (ADS)

Godefroit, Pascal; Golovneva, Lina; Shchepetov, Sergei; Garcia, Géraldine; Alekseev, Pavel

2009-04-01

A latest Cretaceous (68 to 65 million years ago) vertebrate microfossil assemblage discovered at Kakanaut in northeastern Russia reveals that dinosaurs were still highly diversified in Arctic regions just before the Cretaceous-Tertiary mass extinction event. Dinosaur eggshell fragments, belonging to hadrosaurids and non-avian theropods, indicate that at least several latest Cretaceous dinosaur taxa could reproduce in polar region and were probably year-round residents of high latitudes. Palaeobotanical data suggest that these polar dinosaurs lived in a temperate climate (mean annual temperature about 10°C), but the climate was apparently too cold for amphibians and ectothermic reptiles. The high diversity of Late Maastrichtian dinosaurs in high latitudes, where ectotherms are absent, strongly questions hypotheses according to which dinosaur extinction was a result of temperature decline, caused or not by the Chicxulub impact.

Mulptiple Sclerosis, Symptoms, Diagnosis, Treatment and Latest NIH Research | NIH MedlinePlus the Magazine

MedlinePlus

... Multiple Sclerosis: Symptoms, Diagnosis, Treatment and Latest NIH Research Past Issues / Spring 2012 Table of Contents Symptoms ... my MS will ever go away? Latest NIH Research Scientists continue their extensive efforts to create new ...

Latest results from FROST at Jefferson Lab

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ritchie, Barry G.

2014-06-01

The spectrum of broad and overlapping nucleon excitations can be greatly clarified by use of a polarized photon beam incident on a polarized target in meson photoproduction experiments. At Jefferson Lab, a program of such measurements has made use of the Jefferson Lab FROzen Spin Target (FROST). An overview of preliminary results are presented.

Latest Sickle Cell Research | NIH MedlinePlus the Magazine

MedlinePlus

... Special Section: Sickle Cell Disease Latest Sickle Cell Research Past Issues / Winter 2011 Table of Contents In ... treatment on brain function. Other current and future research efforts include studies of: Genetic factors affecting sickle ...

JWST Near-Infrared Detectors: Latest Test Results

NASA Technical Reports Server (NTRS)

Smith, Erin C.; Rauscher, Bernard J.; Alexander, David; Brambora, Clifford K.; Chiao, Meng; Clemons, Brian L.; Derro, Rebecca; Engler, Chuck; Fox, Ori; Garrison, Matthew B.;

Deep Vein Thrombosis: Symptoms, Diagnosis, Treatment and Latest NIH Research | NIH MedlinePlus the Magazine

MedlinePlus

... Vein Thrombosis: Symptoms, Diagnosis, Treatment and Latest NIH Research Past Issues / Spring 2011 Table of Contents Symptoms ... without the monitoring required for warfarin. Latest NIH Research The National Heart, Lung, and Blood Institute (NHLBI) ...

The latest development of antihypertensive medication

NASA Astrophysics Data System (ADS)

Nasution, S.; Rey, I.; Effendi-YS, R.

2018-03-01

Hypertension is the most common risk factor for cardiovascular disease, stroke, renal failure, and death. Recent drug monitoring studies found non-adherence to BP lowering therapy in 25% to 65% of patients with apparent treatment-resistant hypertension (TRH). This review focuses on the latest development of antihypertensive medication, such as vasopeptidase inhibitors, aldosterone synthase inhibitors, Soluble Epoxide Hydrolase Inhibitors, agonists of natriuretic peptide receptor, Vasoactive Intestinal Peptide Receptor Agonist, a novel mineralocorticoid receptor antagonist, inhibitors of aminopeptidase A, dopamine β-hydroxylase inhibitor, intestinal Na+/H+ exchanger 3 inhibitor and other agents.

State of the Nation: A Coast-to-Coast Survey of the Latest Certification Standards

ERIC Educational Resources Information Center

Thomas, Margie

2006-01-01

This article presents the results from a survey that investigated the latest requirements and certification standards for school librarians in each state. In the survey, 42 report they require certification for K-12 library media specialists, meaning that school library candidates must have a bachelor's degree including coursework designed to…

Sofradir latest developments for infrared space detectors

NASA Astrophysics Data System (ADS)

Chorier, Philippe; Delannoy, Anne

2011-06-01

Sofradir is one of the leading companies that develop and produce infrared detectors. Space applications have become a significant activity and Sofradir relies now on 20 years of experience in development and production of MCT infrared detectors of 2nd and 3rd generation for space applications. Thanks to its capabilities and experience, Sofradir is now able to offer high reliability infrared detectors for space applications. These detectors cover various kinds of applications like hyperspectral observation, earth observations for meteorological or scientific purpose and science experiments. In this paper, we present a review of latest Sofradir's development for infrared space applications. A presentation of Sofradir infrared detectors answering hyperspectral needs from visible up to VLWIR waveband will be made. In addition a particular emphasis will be placed on the different programs currently running, with a presentation of the associated results as they relate to performances and qualifications for space use.

The Latest Developments in NASA's Long Duration Balloon Systems

NASA Astrophysics Data System (ADS)

Stilwell, Bryan D.

The Latest Developments in NASA’s Long Duration Balloon Systems Bryan D. Stilwell, bryan.stilwell@csbf.nasa.gov Columbia Scientific Balloon Facility, Palestine, Texas, USA The Columbia Scientific Balloon Facility, located in Palestine, Texas offers the scientific community a high altitude balloon based communications platform. Scientific payload mass can exceed 2722 kg with balloon float altitudes on average of 40000 km and flight duration of up to 100 days. Many developments in electrical systems have occurred over the more than 25 years of long duration flights. This paper will discuss the latest developments in electronic systems related to long duration flights. Over the years, the long duration flights have increased in durations exceeding 56 days. In order to support these longer flights, the systems have had to increase in complexity and reliability. Several different systems that have been upgraded and/or enhanced will be discussed.

Latest-generation catheterization systems enable invasive submillisievert coronary angiography.

PubMed

Kuon, E; Weitmann, K; Hummel, A; Dörr, M; Reffelmann, T; Riad, A; Busch, M C; Felix, S B; Hoffmann, W; Empen, K

2015-05-01

The radiation risk of patients undergoing invasive cardiology remains considerable and includes skin injuries and cancer. To date, submillisievert coronary angiography has not been considered feasible. In 2011, we compared results from 100 consecutive patients undergoing elective coronary angiography using the latest-generation flat-panel angiography system (FPS) with results from examinations by the same operator using 106 historic controls with a conventional image-intensifier system (IIS) that was new in 2002. The median patient exposure parameters were measured as follows: dose-area product (DAP) associated with radiographic cine acquisitions (DAP(R)) and fluoroscopy (DAP(F)) scenes, radiographic frames and runs, and cumulative exposure times for radiography and fluoroscopy. On the FPS as compared to the traditional IIS, radiographic detector entrance dose levels were reduced from 164 to 80 nGy/frame and pulse rates were lowered from 12.5/s to 7.5/s during radiography and from 25/s to 4/s during fluoroscopy. The cardiologist's performance patterns remained comparable over the years: fluoroscopy time was constant and radiography time even slightly increased. Overall patient DAP decreased from 7.0 to 2.4 Gy × cm(2); DAP(R), from 4.2 to 1.7 Gy × cm(2); and DAP(F), from 2.8 to 0.6 Gy × cm(2). Time-adjusted DAP(R)/s decreased from 436 to 130 mGy × cm(2) and DAP(F)/s, from 21.6 to 4.4 mGy × cm(2). Cumulative patient skin dose with the FPS amounted to 67 mGy, and the median (interquartile range) of effective dose was 0.5 (0.3 … 0.7) mSv. Consistent application of radiation-reducing techniques with the latest-generation flat-panel systems enables submillisievert coronary angiography in invasive cardiology.

Latest NASA Instrument Cost Model (NICM): Version VI

NASA Technical Reports Server (NTRS)

Mrozinski, Joe; Habib-Agahi, Hamid; Fox, George; Ball, Gary

2014-01-01

The NASA Instrument Cost Model, NICM, is a suite of tools which allow for probabilistic cost estimation of NASA's space-flight instruments at both the system and subsystem level. NICM also includes the ability to perform cost by analogy as well as joint confidence level (JCL) analysis. The latest version of NICM, Version VI, was released in Spring 2014. This paper will focus on the new features released with NICM VI, which include: 1) The NICM-E cost estimating relationship, which is applicable for instruments flying on Explorer-like class missions; 2) The new cluster analysis ability which, alongside the results of the parametric cost estimation for the user's instrument, also provides a visualization of the user's instrument's similarity to previously flown instruments; and 3) includes new cost estimating relationships for in-situ instruments.

Latest progress from the Daya Bay reactor neutrino experiment

NASA Astrophysics Data System (ADS)

Wang, Zhe; Daya Bay Collaboration

2016-05-01

Recently the Daya Bay reactor neutrino experiment has presented several new results about neutrino and reactor physics after acquiring a large data sample and after gaining a more sophisticated understanding of the experiment. In this talk I will introduce the latest progress made by the experiment including a three-flavor neutrino oscillation analysis using neutron capture on gadolinium, which gave sin2 2θ 13 = 0.084 ± 0.005 and |Δm2 ee| = (2.42 ±0.11) × 10-3 eV2, an independent θ 13 measurement using neutron capture on hydrogen, a search for a light sterile neutrino, and a measurement of the reactor antineutrino flux and spectrum.

SPIRAL2 at GANIL: A world leading ISOL facility at the dawn of the next decade

NASA Astrophysics Data System (ADS)

Gales, S.

2007-07-01

To pursue the investigation of a new territory of nuclei with extreme N/Z, called “terra incognita”, several projects, all aiming at the increase by several orders of magnitude of RIB intensities are now under discussion worldwide. In Europe, two major new projects have been approved recently: FAIR@GSI, using the so-called “in-flight” method, and SPIRAL2@GANIL, based on the ISOL method. The main goal of SPIRAL2 is clearly to extend our knowledge of the limit of existence and the structure of nuclei deeply in the medium and heavy mass region ( A=60-140), which is today an almost unexplored continent. SPIRAL2 is based on a high power, CW, superconducting driver LINAC, delivering 5 mA of deuteron beams at 40 MeV (200 kW) directed on a C converter+ Uranium target and producing therefore more than 10 13 fissions/s. The expected radioactive beam intensities for exotic species in the mass range from A=60 to A=140, of the order of 10 6-10 10 pps will surpass by two order of magnitude any existing facility in the world. These unstable atoms will be available at energies between a few keV/n to 15 MeV/n. The same driver will accelerate high intensity (100 μA to 1 mA), heavier ions up to Ar at 14 MeV/n producing also proton rich exotic nuclei. In applied areas SPIRAL2 is considered as a powerful variable energy neutron source, a must for studying the impact of nuclear fission and fusion on materials. The intensities of these unstable species are excellent opportunities for new tracers and diagnostics either for solid state, material or for radiobiological science and medicine. The technical design has reached the point where SPIRAL2 is ready for construction. Project status and foreseen schedules will be presented. Scientific and technical R&D programs in collaboration with EU and International partners for the facility as well as for the associated innovative new instruments will be discussed.

Association between Latest Activated Sites in the Left Ventricle and Akinetic Segments in Patients with Ischemic Cardiomyopathy.

PubMed

Sadeghian, Hakimeh; Kousari, Aliasghar; Majidi, Shahla; Rezvanfard, Mehrnaz; Kazemisaeid, Ali; Moezzi, Seyed Ali; Vasheghani Farahani, Ali; Abdar Esfahani, Morteza; Sahebjam, Mohammad; Zoroufian, Arezoo; Sadeghian, Afsaneh

2016-07-06

Background: It is not clear whether the latest activation sites in the left ventricle (LV) are matched with infracted regions in patients with ischemic cardiomyopathy (ICM). We aimed to investigate whether the latest activation sites in the LV are in agreement with the region of akinesia in patients with ICM. Methods: Data were analyzed in 106 patients (age = 60.5 ± 12.1 y, male = 88.7%) with ICM (ejection fraction ≤ 35%) who were refractory to pharmacological therapy and were referred to the echocardiography department for an evaluation of the feasibility of cardiac resynchronization therapy. Wall motion abnormalities, time to peak systolic myocardial velocity (Ts) of 6 basal and 6 mid-portion segments of the LV, and 4 frequently used dyssynchrony indices were measured using 2-dimensional echocardiography and tissue Doppler imaging (TDI). To evaluate the influence of the electrocardiographic pattern, we categorized the patients into 2 groups: patients with QRS ≤ 120 ms and those with QRS >120 ms. Results: A total of 1 272 segments were studied. The latest activation sites (with longest Ts) were most frequently located in the mid-anterior (n = 32, 30.2%) and basal-anterior segments (n = 29, 27.4%), while the most common sites of akinesia were the mid-anteroseptal (n = 65, 61.3%) and mid-septal (n = 51, 48.1%) segments. Generally, no significant concordance was found between the latest activated segments and akinesia either in all the patients or in the QRS groups. Detailed analysis within the segments indicated a good agreement between akinesia and delayed activation in the basal-lateral segment solely in the patients with QRS duration ≤ 120 ms (Φ = 0.707; p value ≤ 0.001). Conclusion: The akinetic segment on 2-dimensional echocardiogram was not matched with the latest activation sites in the LV determined by TDI in patients with ICM.

Association between Latest Activated Sites in the Left Ventricle and Akinetic Segments in Patients with Ischemic Cardiomyopathy

PubMed Central

Sadeghian, Hakimeh; Kousari, Aliasghar; Majidi, Shahla; Rezvanfard, Mehrnaz; Kazemisaeid, Ali; Moezzi, Seyed Ali; Vasheghani Farahani, Ali; Abdar Esfahani, Morteza; Sahebjam, Mohammad; Zoroufian, Arezoo; Sadeghian, Afsaneh

2016-01-01

Background: It is not clear whether the latest activation sites in the left ventricle (LV) are matched with infracted regions in patients with ischemic cardiomyopathy (ICM). We aimed to investigate whether the latest activation sites in the LV are in agreement with the region of akinesia in patients with ICM. Methods: Data were analyzed in 106 patients (age = 60.5 ± 12.1 y, male = 88.7%) with ICM (ejection fraction ≤ 35%) who were refractory to pharmacological therapy and were referred to the echocardiography department for an evaluation of the feasibility of cardiac resynchronization therapy. Wall motion abnormalities, time to peak systolic myocardial velocity (Ts) of 6 basal and 6 mid-portion segments of the LV, and 4 frequently used dyssynchrony indices were measured using 2-dimensional echocardiography and tissue Doppler imaging (TDI). To evaluate the influence of the electrocardiographic pattern, we categorized the patients into 2 groups: patients with QRS ≤ 120 ms and those with QRS >120 ms. Results: A total of 1 272 segments were studied. The latest activation sites (with longest Ts) were most frequently located in the mid-anterior (n = 32, 30.2%) and basal-anterior segments (n = 29, 27.4%), while the most common sites of akinesia were the mid-anteroseptal (n = 65, 61.3%) and mid-septal (n = 51, 48.1%) segments. Generally, no significant concordance was found between the latest activated segments and akinesia either in all the patients or in the QRS groups. Detailed analysis within the segments indicated a good agreement between akinesia and delayed activation in the basal-lateral segment solely in the patients with QRS duration ≤ 120 ms (Φ = 0.707; p value ≤ 0.001). Conclusion: The akinetic segment on 2-dimensional echocardiogram was not matched with the latest activation sites in the LV determined by TDI in patients with ICM. PMID:27956911

Latest results of the Tunka Radio Extension

NASA Astrophysics Data System (ADS)

Kostunin, D.; Bezyazeekov, P. A.; Budnev, N. M.; Fedorov, O.; Gress, O. A.; Haungs, A.; Hiller, R.; Huege, T.; Kazarina, Y.; Kleifges, M.; Korosteleva, E. E.; Krömer, O.; Kungel, V.; Kuzmichev, L. A.; Lubsandorzhiev, N.; Marshalkina, T.; Mirgazov, R. R.; Monkhoev, R.; Osipova, E. A.; Pakhorukov, A.; Pankov, L.; Prosin, V. V.; Rubtsov, G. I.; Schröder, F. G.; Wischnewski, R.; Zagorodnikov, A.

2017-06-01

The Tunka Radio Extension (Tunka-Rex) is an antenna array consisting of 63 antennas at the location of the TAIGA facility (Tunka Advanced Instrument for cosmic ray physics and Gamma Astronomy) in Eastern Siberia, nearby Lake Baikal. Tunka-Rex is triggered by the air-Cherenkov array Tunka-133 during clear and moonless winter nights and by the scintillator array Tunka-Grande during the remaining time. Tunka-Rex measures the radio emission from the same air-showers as Tunka-133 and Tunka-Grande, but with a higher threshold of about 100 PeV. During the first stages of its operation, Tunka-Rex has proven, that sparse radio arrays can measure air-showers with an energy resolution of better than 15% and the depth of the shower maximum with a resolution of better than 40 g/cm2. To improve and interpret our measurements as well as to study systematic uncertainties due to interaction models, we perform radio simulations with CORSIKA and CoREAS. In this overview we present the setup of Tunka-Rex, discuss the achieved results and the prospects of mass-composition studies with radio arrays.

The Latest Results from the Focal L-Band Array for the Green Bank Telescope (FLAG), the World's (Current) Most Sensitive Phased Array Feed

NASA Astrophysics Data System (ADS)

Pingel, Nickolas; Pisano, D. J.

2018-01-01

Phased Array Feeds (PAFs) represent the next revolution in radio astronomy instrumentation. I will present results from the latest commissioning run from the Focal L-Band Array for the Green Bank telescope (FLAG), which holds the current world record for PAF sensitivity. Since we are able to operate at system temperatures comparable with the traditional GBT single pixel L-Band feed, the increase in the field-of-view provided by the beamforming capabilities of PAFs results in a dramatic (a factor of 5) increase in survey speeds. In particular, FLAG can probe similar neutral hydrogen column density regimes over a 4 sq. deg region in 24.6 minutes as opposed to 4.1 hours in an equivalent single pixel map (excluding observing overhead). In addition to comparisons between data taken with FLAG and the single-pixel L-Band feed, I will also discuss the technical aspects of the observing procedure, data reduction, and the transition path for FLAG from an instrument that is principle-investigator run to one that is general use. These FLAG results provide a very encouraging outlook on how the GBT will continue to compete with current and planned radio telescope facilities.

North Korea’s Nuclear Weapons: Latest Developments

DTIC Science & Technology

2007-12-05

time shown less confidence about what the scope of the program might be. Further, although seismographs registered the October 9, 2006, detonation and...298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 North Korea’s Nuclear Weapons: Latest Developments Summary This report summarizes what is known from...States would lead disablement activities and provide the initial funding for those activities.15 Disablement indicates a physical measure to make it

Teacher Evaluation in China: Latest Trends and Future Directions

ERIC Educational Resources Information Center

Liu, Shujie; Zhao, Decheng

2013-01-01

With the implementation of teacher performance pay in 2009 in China, teacher performance evaluation has become a heated topic. This research study follows up on two previous studies of teacher evaluation in China and continues the dialog by analyzing the latest trends in the context of teacher performance pay. There were two sources of information…

North Korea’s Nuclear Weapons: Latest Developments

DTIC Science & Technology

2007-11-21

time shown less confidence about what the scope of the program might be. Further, although seismographs registered the October 9, 2006, detonation...298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 North Korea’s Nuclear Weapons: Latest Developments Summary This report summarizes what is known from...provide the initial funding for those activities.15 Disablement indicates a physical measure to make it difficult to restart operation of a facility while

Laser scan of the Grimming Mts. (Austria) with the latest LiDAR VZ-4000 equipment: preliminary results

NASA Astrophysics Data System (ADS)

Bauer, Harald; Hatzenbichler, Georg; Amon, Philipp; Fallah, Mohammad; Tari, Gabor; Grasemann, Bernhard

2013-04-01

As part of a cooperation project between OMV, RIEGL and the University of Vienna the new LiDAR (Light Detection and Ranging) VZ-4000 laser scanner was tested at the Grimming Mts. of the Eastern Alps in Austria. The prominent Grimming Mts. lies in the eastern part of the Dachstein Massif at the southern margin of the Northern Calcareous Alps. The Grimming, with a peak of 2,351 m above sea level, is one of the highest isolated mountains in Europe. Because of its spectacular topography, the Grimming has been used as an important surface reference mark since 1822. From a structural geology standpoint, the Grimming forms a huge antiform made up of dominantly well-bedded Triassic Dachstein Limestone. Because of the relatively well exposed bedrock surfaces above the tree-line and the fairly complex internal structure, the Grimming Mts. provides an ideal target for testing new high resolution laser scan techniques and devices. The maximum distance from the scanning positions on the nearby valley floor to the mountain face was about 4,500 m and the generated point cloud has an average resolution of 25 points per square meter. The purpose of this work was to test the latest version of the high resolution LiDAR laser equipment in a setting which falls beyond the capabilities of most existing LiDAR devices. The results of the pilot study include high-resolution spatial data on bedding planes, fault planes and the thickness variations of individual beds within the Dachstein Limestone. For the first time, the data obtained can be directly used to generate the proper 3D geometry of folds and faults observed on the Grimming Mts. This leads to a modern understanding of this prominent Alpine anticline in terms of structural geology.

Zika Virus: the Latest Newcomer

PubMed Central

Saiz, Juan-Carlos; Vázquez-Calvo, Ángela; Blázquez, Ana B.; Merino-Ramos, Teresa; Escribano-Romero, Estela; Martín-Acebes, Miguel A.

2016-01-01

Since the beginning of this century, humanity has been facing a new emerging, or re-emerging, virus threat almost every year: West Nile, Influenza A, avian flu, dengue, Chikungunya, SARS, MERS, Ebola, and now Zika, the latest newcomer. Zika virus (ZIKV), a flavivirus transmitted by Aedes mosquitoes, was identified in 1947 in a sentinel monkey in Uganda, and later on in humans in Nigeria. The virus was mainly confined to the African continent until it was detected in south-east Asia the 1980’s, then in the Micronesia in 2007 and, more recently in the Americas in 2014, where it has displayed an explosive spread, as advised by the World Health Organization, which resulted in the infection of hundreds of thousands of people. ZIKV infection was characterized by causing a mild disease presented with fever, headache, rash, arthralgia, and conjunctivitis, with exceptional reports of an association with Guillain–Barre syndrome (GBS) and microcephaly. However, since the end of 2015, an increase in the number of GBS associated cases and an astonishing number of microcephaly in fetus and new-borns in Brazil have been related to ZIKV infection, raising serious worldwide public health concerns. Clarifying such worrisome relationships is, thus, a current unavoidable goal. Here, we extensively review what is currently known about ZIKV, from molecular biology, transmission routes, ecology, and epidemiology, to clinical manifestations, pathogenesis, diagnosis, prophylaxis, and public health. PMID:27148186

Latest Neoproterozoic basin inversion of the Beardmore Group, central Transantarctic Mountains, Antarctica

NASA Astrophysics Data System (ADS)

Goodge, John W.

1997-08-01

Structural and age relationships in Beardmore Group rocks in the central Transantarctic Mountains of Antarctica indicate that they experienced a single deformation in latest Neoproterozoic to early Paleozoic time. New structural data contrast with earlier suggestions that Beardmore rocks record two orogenic deformations, one of the early Paleozoic Ross orogeny and a distinct earlier tectonic event of presumed Neoproterozoic age referred to as the Beardmore orogeny. In the Nimrod Glacier area, Beardmore metasedimentary rocks contain only a single set of geometrically related regional structures associated with the development of upright, large- and small-scale flexural-slip folds. Deformation of Beardmore strata involved west directed contraction of modest regional strain at relatively high crustal levels. Existing ages of detrital zircons from the Cobham and Goldie formations constrain Beardmore Group deposition to be younger than ˜600 Ma. This is significantly younger than previous age estimates and suggests that Beardmore deposition may be closely linked to a latest Neoproterozoic East Antarctic rift margin. The lack of structural evidence for polyphase deformation and the relatively young depositional age for the Beardmore Group thus raises the question of a temporally and/or technically unique Beardmore orogeny. Here I suggest that Beardmore shortening may be related to tectonic inversion of East Antarctic marginal-basin strata because of localized compression during proto-Pacific seafloor spreading. Basin inversion is but one stage in a protracted Ross tectonic cycle of rifting, tectonic inversion, subduction initiation, and development of a mature convergent continental margin during latest Neoproterozoic and early Paleozoic time. The term "Beardmore orogeny" has little meaning as an event of orogenic status, and it should be abandoned. Recognition of this latest Neoproterozoic history reinforces the view that the broader Ross orogeny was not a single event

Latest advances in molecular imaging instrumentation.

PubMed

Pichler, Bernd J; Wehrl, Hans F; Judenhofer, Martin S

2008-06-01

This review concentrates on the latest advances in molecular imaging technology, including PET, MRI, and optical imaging. In PET, significant improvements in tumor detection and image resolution have been achieved by introducing new scintillation materials, iterative image reconstruction, and correction methods. These advances enabled the first clinical scanners capable of time-of-flight detection and incorporating point-spread-function reconstruction to compensate for depth-of-interaction effects. In the field of MRI, the most important developments in recent years have mainly been MRI systems with higher field strengths and improved radiofrequency coil technology. Hyperpolarized imaging, functional MRI, and MR spectroscopy provide molecular information in vivo. A special focus of this review article is multimodality imaging and, in particular, the emerging field of combined PET/MRI.

Latest-Generation Transcatheter Aortic Valve Replacement Devices and Procedures.

PubMed

Chamandi, Chekrallah; Puri, Rishi; Rodriguez-Gabella, Tania; Rodés-Cabau, Josep

2017-09-01

Transcatheter aortic valve replacement (TAVR) is a well-established treatment for patients with severe symptomatic aortic stenosis who are at high or prohibitive surgical risk. More recently, TAVR has emerged as a valid alternative to surgical aortic valve replacement for treating intermediate-risk patients, and several studies are currently evaluating the role of TAVR in low-risk patients. Transcatheter heart valve (THV) technologies have evolved considerably over time, and important iterations have been implemented in many of the latest-generation devices to (1) reduce the size and improve delivery system properties; (2) improve valve deployment, repositioning, and retrievability; and (3) reduce paravalvular leaks. This article reviews the main characteristics of, and clinical results associated with, the newer-generation THVs while providing an overview of novel TAVR indications. Copyright © 2017 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.

Left ventricular lead placement in the latest activated region guided by coronary venous electroanatomic mapping.

PubMed

Rad, Masih Mafi; Blaauw, Yuri; Dinh, Trang; Pison, Laurent; Crijns, Harry J; Prinzen, Frits W; Vernooy, Kevin

2015-01-01

Left ventricular (LV) lead placement in the latest activated region is an important determinant of response to cardiac resynchronization therapy (CRT). We investigated the feasibility of coronary venous electroanatomic mapping (EAM) to guide LV lead placement to the latest activated region. Twenty-five consecutive CRT candidates with left bundle-branch block underwent intra-procedural coronary venous EAM using EnSite NavX. A guidewire was used to map the coronary veins during intrinsic activation, and to test for phrenic nerve stimulation (PNS). The latest activated region, defined as the region with an electrical delay >75% of total QRS duration, was located anterolaterally in 18 (basal, n = 10; mid, n = 8) and inferolaterally in 6 (basal, n = 3; mid, n = 3). In one patient, identification of the latest activated region was impeded by limited coronary venous anatomy. In patients with >1 target vein (n = 12), the anatomically targeted inferolateral vein was rarely the vein with maximal electrical delay (n = 3). A concordant LV lead position was achieved in 18 of 25 patients. In six patients, this was hampered by PNS (n = 4), lead instability (n = 1), and coronary vein stenosis (n = 1). Coronary venous EAM can be used intraprocedurally to guide LV lead placement to the latest activated region free of PNS. This approach especially contributes to optimization of LV lead electrical delay in patients with multiple target veins. Conventional anatomical LV lead placement strategy does not target the vein with maximal electrical delay in many of these patients. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2014. For permissions please email: journals.permissions@oup.com.

Non-Formal Education Implementations in Turkey: Issues and Latest Challenges

ERIC Educational Resources Information Center

Bilir, Mehmet

2007-01-01

The aim of this article is to analyse the latest implementations and issues raised in Turkish non-formal education from a historical perspective in Turkey. The high population rate and lack of adequate educational opportunities for adults and migration from rural areas to urban areas caused many educational, social and cultural problems in…

Latest innovations for tattoo and permanent makeup removal.

PubMed

Mao, Johnny C; DeJoseph, Louis M

2012-05-01

The goal of this article is to reveal the latest techniques and advances in laser removal of both amateur and professional tattoos, as well as cosmetic tattoos and permanent makeup. Each pose different challenges to the removing physician, but the goal is always the same: removal without sequelae. The authors' technique is detailed, and discussion of basic principles of light reflection, ink properties, effects of laser energy and heat, and outcomes and complications of tattoo removal are presented. Copyright © 2012 Elsevier Inc. All rights reserved.

Latest Trends of Vacuum Circuit Breaker and Related Technologies

NASA Astrophysics Data System (ADS)

Kozono, Hideaki; Tanimizu, Toru

Vacuum Circuit Breakers (VCBs) have been widely used for medium voltage level, because of their performance: compact size, light weight, maintenance free operations and environment-friendly characteristics. They become most comfortable breakers for our needs from other breakers: oil, air, magnetic blast and gas. In this paper the history of vacuum, and latest trends of circuit breakers and related technologies are described, as well as merits or demerits of using vacuum technologies.

Supportive Care in Hemato-Oncology: A Review in Light of the Latest Guidelines

PubMed Central

Gündüz, Eren; Gülbaş, Zafer

2012-01-01

Recent developments in cancer therapy have resulted in increases in treatment success rates and survival. One of thebasic goals of such therapy is improving patient quality of life. Chemotherapy protocols for solid or hematologicalmalignancies-most of which include multiple agents-negatively impact patient quality of life. Additionally, there havebeen developments in supportive care, which seeks to ameliorate or minimize the negative effects of chemotherapy.Herein we present a review and brief summarization of some of the agents used for supportive care in cancer patientsin light of the latest guidelines. PMID:24744617

MESSENGER Team Presents Latest Science Results

NASA Image and Video Library

2009-04-30

This mosaic was assembled using NAC images acquired as the MESSENGER spacecraft approached the planet during the mission second Mercury flyby The Rembrandt impact basin is seen at the center of the mosaic.

Latest Results from MINOS and MINOS+

DOE PAGES

De Rijck, Simon

2017-07-27

The MINOS and MINOS+ experiments collected accelerator beam neutrino and antineutrino data for 11 years corresponding to peak energies of 3 GeV and 6 GeV, respectively, over a baseline of 735 km. These proceedings report on new limits and constraints set by MINOS and MINOS+ in and beyond the standard three-flavor paradigm. The atmospheric neutrino mass splitting in the three-flavor model is measured to be (2.42 ± 0.09) × 10 -3 eV 2 for normal mass ordering andmore » $$-({2.48}_{-0.11}^{+0.09})\\times {10}^{-3}{\\ {\\rm{eV}}}^{2}$$ for inverted mass ordering. Constraints are set on sterile neutrinos and antineutrinos in the four-flavor model by looking for sterile-driven ν μ and $${\\bar{\

Looking Ahead: A Report on the Latest Survey Results.

ERIC Educational Resources Information Center

Technology & Learning, 1995

1995-01-01

Reports on the results of a survey of software publishers and market researchers for educators that was conducted to determine development, purchasing, and upgrading plans for educational computer technology. Highlights include operating systems, including Macintosh, DOS, and Windows; equipment needs, including memory, monitors, and special…

Latest results from the GreenHouse gas Observations of the Stratosphere and Troposphere (GHOST) airborne shortwave infrared spectrometer

NASA Astrophysics Data System (ADS)

Humpage, Neil; Boesch, Hartmut; Palmer, Paul; Vick, Andy

2017-04-01

GHOST is a novel, compact shortwave infrared grating spectrometer, designed for remote sensing of tropospheric columns of greenhouse gases (GHGs) from an airborne platform. GHOST observes solar radiation at medium to high spectral resolution which has been reflected by the surface, using similar methods to those used by polar orbiting satellites such as the JAXA GOSAT mission, the NASA OCO-2 mission and the forthcoming Copernicus Sentinel 5-Precursor. By using an original design comprising optical fibre inputs along with a single diffraction grating and detector array, GHOST is able to observe CO2 absorption bands centred around 1.61 μm and 2.06 μm (the same wavelength regions used by OCO-2 and GOSAT) whilst simultaneously measuring CH4 absorption at 1.65 μm (also observed by GOSAT), and both CH4 and CO at 2.30 μm (to be observed by Sentinel 5-P once launched later in 2017). The overlapping spectral ranges and comparable spectral resolutions mean that GHOST has unique potential for providing validation opportunities for these platforms, particularly over the ocean where ground-based validation measurements are not available. Here we present the latest results from the spectral analysis, using an optimal estimation based retrieval method, of CO2 and CH4 from GHOST flight spectra for the 1.6 μm band which utilise recently updated laboratory calibration measurements. GHOST took part in two science flights on board the NASA Global Hawk unmanned aerial vehicle based at the Armstrong Flight Research Centre in Edwards, California, in March 2015. These flights involved long approximately north-south transects over the eastern Pacific Ocean. In addition to observing spatial trends in GHG column concentrations over a regional scale, the second of these flights (on 10th March) allows inter-comparisons of GHOST retrievals with observations from OCO-2 and GOSAT, which both passed directly over the Global Hawk during clear sky conditions. We will show results from these

The endocannabinoid system: a general view and latest additions

PubMed Central

Petrocellis, Luciano De; Cascio, Maria Grazia; Marzo, Vincenzo Di

2004-01-01

After the discovery, in the early 1990s, of specific G-protein-coupled receptors for marijuana's psychoactive principle Δ9-tetrahydrocannabinol, the cannabinoid receptors, and of their endogenous agonists, the endocannabinoids, a decade of investigations has greatly enlarged our understanding of this altogether new signalling system. Yet, while the finding of the endocannabinoids resulted in a new effort to reveal the mechanisms regulating their levels in the brain and peripheral organs under physiological and pathological conditions, more endogenous substances with a similar action, and more molecular targets for the previously discovered endogenous ligands, anandamide and 2-arachidonoylglycerol, or for some of their metabolites, were being proposed. As the scenario becomes subsequently more complicated, and the experimental tasks to be accomplished correspondingly more numerous, we briefly review in this article the latest ‘additions' to the endocannabinoid system together with earlier breakthroughs that have contributed to our present knowledge of the biochemistry and pharmacology of the endocannabinoids. PMID:14744801

Drug-resistant Neisseria gonorrhoeae: latest developments.

PubMed

Suay-García, B; Pérez-Gracia, M T

2017-07-01

Gonorrhea is the second most frequently reported notifiable disease in the United States and is becoming increasingly common in Europe. The purpose of this review was to assess the current state of drug-resistant Neisseria gonorrhoeae in order to evaluate future prospects for its treatment. An exhaustive literature search was conducted to include the latest research regarding drug resistance and treatment guidelines for gonorrhea. Gonococci have acquired all known resistance mechanisms to all antimicrobials used for treatment. Currently, the European Union, the United States, and the United Kingdom have established surveillance programs to assess, on a yearly basis, the development of gonococcal resistance. Current treatment guidelines are being threatened by the increasing number of ceftriaxone-, cefixime-, and azithromycin-resistant N. gonorrhoeae strains being detected worldwide. This has led the scientific community to develop new treatment options with new molecules in order to persevere in the battle against this "superbug".

Characteristics in mineral compositions of lunar latest mare volcanism revealed from spectral data

NASA Astrophysics Data System (ADS)

Kato, S.; Morota, T.; Yamaguchi, Y.; Watanabe, S.; Otake, H.; Ohtake, M.; Nimura, T.

2016-12-01

Lunar mare basalts provide insights into the composition and thermal history of the lunar mantle. According to crater counting analysis with remote sensing data, the ages of mare basalts suggest a first peak of magma activity at 3.2-3.8 Ga and a second peak at 2 Ga. In order to understand the mechanism for causing the second peak and its magma source, we reassess the correlation between the titanium contents and the eruption ages of mare basalt units using the compositional and chronological data updated by SELENE (Kaguya). In the Procellarum KREEP Terrane, where the latest mare basalt units are concentrated, an increase in the mean titanium content is observed in the Eratosthenian Period, as reported by previous studies. We found that, however, a rapid increase in mean titanium content occurred near 2.3 Ga. This result suggests that the magma source of the mare basalts changed at this particular age. Moreover, the high-titanium basaltic eruptions are correlated with the second peak in mare volcanism at 2 Ga. The latest mare volcanism may have been induced by a super-hot plume originating from the core-mantle boundary. In this study, to reveal the difference between the volcanic activities before and after 2.3 Ga, we developed the method to estimate the mineral components and elemental compositions of lunar mare basalts by using the Kaguya Spectral Profiler data. We will introduce the detail of the method and discuss about the difference between the mineral compositions of mare basalts before and after 2.3 Ga based on our preliminary results.

Thumbnail Sketches: The Chemistry of Printed Circuit Substrates: Some of the Latest Developments.

ERIC Educational Resources Information Center

Freeman, James H.

1984-01-01

Discusses some of the latest developments in the chemistry of printed circuit substrates. Topics considered include soldering, dicy (a catalyst), Kevlar (an aramid polymer fiber), maleimide copolymers, and flexible circuits. (JN)

First Clarkforkian Equivalent Land Mammal Age in the Latest Paleocene Basal Sparnacian Facies of Europe: Fauna, Flora, Paleoenvironment and (Bio)stratigraphy

PubMed Central

Smith, Thierry; Quesnel, Florence; De Plöeg, Gaël; De Franceschi, Dario; Métais, Grégoire; De Bast, Eric; Solé, Floréal; Folie, Annelise; Boura, Anaïs; Claude, Julien; Dupuis, Christian; Gagnaison, Cyril; Iakovleva, Alina; Martin, Jeremy; Maubert, François; Prieur, Judicaël; Roche, Emile; Storme, Jean-Yves; Thomas, Romain; Tong, Haiyan; Yans, Johan; Buffetaut, Eric

2014-01-01

The Paleocene-Eocene Thermal Maximum (PETM) is correlated with the first occurrences of earliest modern mammals in the Northern Hemisphere. The latest Paleocene Clarkforkian North American Land Mammal Age, that has yielded rodents and carnivorans, is the only exception to this rule. However, until now no pre-PETM localities have yielded modern mammals in Europe or Asia. We report the first Clarkforkian equivalent Land Mammal Age in the latest Paleocene deposits of the basal Sparnacian facies at Rivecourt, in the north-central part of the Paris Basin. The new terrestrial vertebrate and macroflora assemblages are analyzed through a multidisciplinary study including sedimentologic, stratigraphic, isotopic, and palynological aspects in order to reconstruct the paleoenvironment and to evaluate biochronologic and paleogeographic implications. The mammals are moderately diverse and not abundant, contrary to turtles and champsosaurs. The macroflora is exceptional in preservation and diversity with numerous angiosperms represented by flowers, fruits, seeds and wood preserved as lignite material, revealing an abundance of Arecaceae, Betulaceae, Icacinaceae, Menispermaceae, Vitaceae and probably Cornaceae. Results indicate a Late Paleocene age based on carbon isotope data, palynology and vertebrate occurrences such as the choristoderan Champsosaurus, the arctocyonid Arctocyon, and the plesiadapid Plesiadapis tricuspidens. However, several mammal species compare better with the earliest Eocene. Among these, the particular louisinid Teilhardimys musculus, also recorded from the latest Paleocene of the Spanish Pyrenees, suggests a younger age than the typical MP6 reference level. Nevertheless, the most important aspect of the Rivecourt fauna is the presence of dental remains of a rodent and a “miacid” carnivoran, attesting to the presence of two modern mammalian orders in the latest Paleocene of Europe. Interestingly, these two groups are also the only modern groups recorded

First Clarkforkian equivalent Land Mammal Age in the latest Paleocene basal Sparnacian facies of Europe: fauna, flora, paleoenvironment and (bio)stratigraphy.

PubMed

Smith, Thierry; Quesnel, Florence; De Plöeg, Gaël; De Franceschi, Dario; Métais, Grégoire; De Bast, Eric; Solé, Floréal; Folie, Annelise; Boura, Anaïs; Claude, Julien; Dupuis, Christian; Gagnaison, Cyril; Iakovleva, Alina; Martin, Jeremy; Maubert, François; Prieur, Judicaël; Roche, Emile; Storme, Jean-Yves; Thomas, Romain; Tong, Haiyan; Yans, Johan; Buffetaut, Eric

2014-01-01

The Paleocene-Eocene Thermal Maximum (PETM) is correlated with the first occurrences of earliest modern mammals in the Northern Hemisphere. The latest Paleocene Clarkforkian North American Land Mammal Age, that has yielded rodents and carnivorans, is the only exception to this rule. However, until now no pre-PETM localities have yielded modern mammals in Europe or Asia. We report the first Clarkforkian equivalent Land Mammal Age in the latest Paleocene deposits of the basal Sparnacian facies at Rivecourt, in the north-central part of the Paris Basin. The new terrestrial vertebrate and macroflora assemblages are analyzed through a multidisciplinary study including sedimentologic, stratigraphic, isotopic, and palynological aspects in order to reconstruct the paleoenvironment and to evaluate biochronologic and paleogeographic implications. The mammals are moderately diverse and not abundant, contrary to turtles and champsosaurs. The macroflora is exceptional in preservation and diversity with numerous angiosperms represented by flowers, fruits, seeds and wood preserved as lignite material, revealing an abundance of Arecaceae, Betulaceae, Icacinaceae, Menispermaceae, Vitaceae and probably Cornaceae. Results indicate a Late Paleocene age based on carbon isotope data, palynology and vertebrate occurrences such as the choristoderan Champsosaurus, the arctocyonid Arctocyon, and the plesiadapid Plesiadapis tricuspidens. However, several mammal species compare better with the earliest Eocene. Among these, the particular louisinid Teilhardimys musculus, also recorded from the latest Paleocene of the Spanish Pyrenees, suggests a younger age than the typical MP6 reference level. Nevertheless, the most important aspect of the Rivecourt fauna is the presence of dental remains of a rodent and a "miacid" carnivoran, attesting to the presence of two modern mammalian orders in the latest Paleocene of Europe. Interestingly, these two groups are also the only modern groups recorded

Latest generation, wide-angle, high-definition colonoscopes increase adenoma detection rate.

PubMed

Adler, Andreas; Aminalai, Alireza; Aschenbeck, Jens; Drossel, Rolf; Mayr, Michael; Scheel, Mathias; Schröder, Andreas; Yenerim, Timur; Wiedenmann, Bertram; Gauger, Ulrich; Roll, Stephanie; Rösch, Thomas

2012-02-01

Improvements to endoscopy imaging technologies might improve detection rates of colorectal cancer and patient outcomes. We compared the accuracy of the latest generation of endoscopes with older generation models in detection of colorectal adenomas. We compared data from 2 prospective screening colonoscopy studies (the Berlin Colonoscopy Project 6); each study lasted approximately 6 months and included the same 6 colonoscopists, who worked in private practice. Participants in group 1 (n = 1256) were all examined by using the latest generation of wide-angle, high-definition colonoscopes that were manufactured by the same company. Individuals in group 2 (n = 1400) were examined by endoscopists who used routine equipment (a mixture of endoscopes from different companies; none of those used to examine group 1). The adenoma detection rate was calculated on the basis of the number of all adenomas/number of all patients. There were no differences in patient parameters or withdrawal time between groups (8.0 vs 8.2 minutes). The adenoma detection rate was significantly higher in group 1 (0.33) than in group 2 (0.27; P = .01); a greater number of patients with least 1 adenoma were identified in group 1 (22.1%) than in group 2 (18.2%; P = .01). A higher percentage of high-grade dysplastic adenomas were detected in group 1 (1.19%) than in group 2 (0.57%), but this difference was not statistically significant (P = .06). The latest generation of wide-angle, high-definition colonoscopes improves rates of adenoma detection by 22%, compared with mixed, older technology endoscopes used in routine private practice. These findings might affect definitions of quality control parameters for colonoscopy screening for colorectal cancer. Copyright © 2012 AGA Institute. Published by Elsevier Inc. All rights reserved.

Nebraska Governor, Energy Company Chiefs to See Latest in Renewable Energy

Science.gov Websites

developments in wind, ethanol, solar and building technologies at the U.S. Department of Energy's National the latest in wind technology, " Nelson said. "The lab also is pioneering ethanol production ethanol production." The governor said the U.S. Department of Energy agreed to provide $25,000 to pay

Latest results from meson photoproduction at ELSA and MAMI

NASA Astrophysics Data System (ADS)

Krusche, B.

2014-06-01

Photoproduction of mesons plays a key role for the investigation of the excitation spectrum of the nucleon and thus for our understanding of the strong interaction in the non-perturbative regime. In this contribution we discuss recent results from the experiments at the tagged photon beams of the electron accelerators ELSA in Bonn and MAMI in Mainz. They include the measurement of cross sections and (double) polarization observables for single meson production and production of meson pairs off free protons as well as of quasi-free nucleons bound in light nuclei (in particular the deuteron).

New Mid-Cretaceous (Latest Albian) Dinosaurs from Winton, Queensland, Australia

PubMed Central

Hocknull, Scott A.; White, Matt A.; Tischler, Travis R.; Cook, Alex G.; Calleja, Naomi D.; Sloan, Trish; Elliott, David A.

2009-01-01

Background Australia's dinosaurian fossil record is exceptionally poor compared to that of other similar-sized continents. Most taxa are known from fragmentary isolated remains with uncertain taxonomic and phylogenetic placement. A better understanding of the Australian dinosaurian record is crucial to understanding the global palaeobiogeography of dinosaurian groups, including groups previously considered to have had Gondwanan origins, such as the titanosaurs and carcharodontosaurids. Methodology/Principal Findings We describe three new dinosaurs from the late Early Cretaceous (latest Albian) Winton Formation of eastern Australia, including; Wintonotitan wattsi gen. et sp. nov., a basal titanosauriform; Diamantinasaurus matildae gen. et sp. nov., a derived lithostrotian titanosaur; and Australovenator wintonensis gen. et sp. nov., an allosauroid. We compare an isolated astragalus from the Early Cretaceous of southern Australia; formerly identified as Allosaurus sp., and conclude that it most-likely represents Australovenator sp. Conclusion/Significance The occurrence of Australovenator from the Aptian to latest Albian confirms the presence in Australia of allosauroids basal to the Carcharodontosauridae. These new taxa, along with the fragmentary remains of other taxa, indicate a diverse Early Cretaceous sauropod and theropod fauna in Australia, including plesiomorphic forms (e.g. Wintonotitan and Australovenator) and more derived forms (e.g. Diamantinasaurus). PMID:19584929

Constraining viscous dark energy models with the latest cosmological data

NASA Astrophysics Data System (ADS)

Wang, Deng; Yan, Yang-Jie; Meng, Xin-He

2017-10-01

Based on the assumption that the dark energy possessing bulk viscosity is homogeneously and isotropically permeated in the universe, we propose three new viscous dark energy (VDE) models to characterize the accelerating universe. By constraining these three models with the latest cosmological observations, we find that they just deviate very slightly from the standard cosmological model and can alleviate effectively the current H_0 tension between the local observation by the Hubble Space Telescope and the global measurement by the Planck Satellite. Interestingly, we conclude that a spatially flat universe in our VDE model with cosmic curvature is still supported by current data, and the scale invariant primordial power spectrum is strongly excluded at least at the 5.5σ confidence level in the three VDE models as the Planck result. We also give the 95% upper limits of the typical bulk viscosity parameter η in the three VDE scenarios.

Latest research progress on food waste management: a comprehensive review

NASA Astrophysics Data System (ADS)

Zhu, Shangzhen; Gao, Hetong; Duan, Lunbo

2018-05-01

Since a large amount of food supplying is provided as a basic line measuring increasing residents’ life standard, food waste has become progressively numeral considerable. Much attention has been drawn to this problem. This work gave an overview on latest researches about anaerobic digestion, composting, generalized management and other developments on management of food waste. Different technologies were introduced and evaluated. Further views on future research in such a field were proposed.

Left Ventricular Lead Placement Targeted at the Latest Activated Site Guided by Electrophysiological Mapping in Coronary Sinus Branches Improves Response to Cardiac Resynchronization Therapy.

PubMed

Liang, Yanchun; Yu, Haibo; Zhou, Weiwei; Xu, Guoqing; Sun, Y I; Liu, Rong; Wang, Zulu; Han, Yaling

2015-12-01

Electrophysiological mapping (EPM) in coronary sinus (CS) branches is feasible for guiding LV lead placement to the optimal, latest activated site at cardiac resynchronization therapy (CRT) procedures. However, whether this procedure optimizes the response to CRT has not been demonstrated. This study was to evaluate effects of targeting LV lead at the latest activated site guided by EPM during CRT. Seventy-six consecutive patients with advanced heart failure who were referred for CRT were divided into mapping (MG) and control groups (CG). In MG, the LV lead, also used as a mapping bipolar electrode, was placed at the latest activated site determined by EPM in CS branches. In CG, conventional CRT procedure was performed. Patients were followed for 6 months after CRT. Baseline characteristics were comparable between the 2 groups. In MG (n = 29), EPM was successfully performed in 85 of 91 CS branches during CRT. A LV lead was successfully placed at the latest activated site guided by EPM in 27 (93.1%) patients. Compared with CG (n = 47), MG had a significantly higher rate (86.2% vs. 63.8%, P = 0.039) of response (>15% reduction in LV end-systolic volume) to CRT, a higher percentage of patients with clinical improvement of ≥2 NYHA functional classes (72.4% vs. 44.7%, P = 0.032), and a shorter QRS duration (P = 0.004). LV lead placed at the latest activated site guided by EPM resulted in a significantly greater CRT response, and a shorter QRS duration. © 2015 Wiley Periodicals, Inc.

Latest news from the High Altitude Water Cherenkov Observatory

NASA Astrophysics Data System (ADS)

González Muñoz, A.; HAWC Collaboration

2016-07-01

The High Altitude Water Cherenkov Observatory is an air shower detector designed to study very-high-energy gamma rays (˜ 100 GeV to ˜ 100 TeV). It is located in the Pico de Orizaba National Park, Mexico, at an elevation of 4100 m. HAWC started operations since August 2013 with 111 tanks and in April of 2015 the 300 tanks array was completed. HAWC's unique capabilities, with a field of view of ˜ 2 sr and a high duty cycle of 5%, allow it to survey 2/3 of the sky every day. These features makes HAWC an excellent instrument for searching new TeV sources and for the detection of transient events, like gamma-ray bursts. Moreover, HAWC provides almost continuous monitoring of already known sources with variable gamma-ray fluxes in most of the northern and part of the southern sky. These observations will bring new information about the acceleration processes that take place in astrophysical environments. In this contribution, some of the latest scientific results of the observatory will be presented.

Latest developments for low-power infrared laser-based trace gas sensors for sensor networks

NASA Astrophysics Data System (ADS)

So, Stephen; Thomazy, David; Wang, Wen; Marchat, Oscar; Wysocki, Gerard

2011-09-01

Academic and industrial researchers require ultra-low power, compact laser based trace-gas sensor systems for the most demanding environmental and space-borne applications. Here the latest results from research projects addressing these applications will be discussed: 1) an ultra-compact CO2 sensor based on a continuous wave quantum cascade laser, 2) an ultra-sensitive Faraday rotation spectrometer for O2 detection, 3) a fully ruggedized compact and low-power laser spectrometer, and 4) a novel non-paraxial nonthin multipass cell. Preliminary tests and projection for performance of future sensors based on this technology is presented.

Ocean anoxia did not cause the Latest Permian Extinction

NASA Astrophysics Data System (ADS)

Proemse, Bernadette C.; Grasby, Stephen E.; Wieser, Michael E.; Mayer, Bernhard; Beauchamp, Benoit

2014-05-01

The Latest Permian Extinction (LPE, ~252 million years ago) was a turning point in the history of life on Earth with a loss of ~96% of all marine species and ~70% of all terrestrial species. While, the event undoubtedly shaped the evolution of life its cause remains enigmatic. A leading hypothesis is that the global oceans became depleted in oxygen (anoxia). In order to test this hypothesis we investigated a proxy for marine oxygen levels (molybdenum isotopic composition) in shale across the LPE horizon located on the subtropical northwest margin of Pangea at that time. We studied two sedimentary records in the Sverdrup basin, Canadian High Arctic: Buchanan Lake (eastern Axel Heiberg Island; 79° 26.1'N, 87° 12.6'W), representing a distal deep-water slope environment, and West Blind Fiord (southwest Ellesmere Island; 78° 23.9'N, 85° 57.2'W), representing a deep outer shelf environment (below storm wave base). The molybdenum isotopic composition (δ98/95Mo) of sediments has recently become a powerful tool as a paleo-oceanographic proxy of marine oxygen levels. Sample preparation was carried out in a metal-free clean room facility in the isotope laboratory of the Department of Physics and Astronomy, University of Calgary, Canada, that is supplied by HEPA-filtered air. Molybdenum isotope ratios were determined on a Thermo Scientific multi-collector inductively coupled plasma mass spectrometer (MC-ICP-MS) with an uncertainty better than ±0.10o for δ98/95Mo values. Results from the Buchanan Lake section show a large shift in δ98/95Mo values from 2.02o to +2.23o at the extinction horizon, consistent with onset of euxinic conditions. In contrast, West Blind Fiord shales, representing the sub-storm wave base shelf environment, show little change in the molybdenum isotopic composition (1.34o to +0.05), indicating ongoing oxic conditions across the LPE (Proemse et al., 2013). Our results suggest that areas of the Pangea continental shelf (North West Pangea) experienced

Evaluating Surface Flux Results from CERES-FLASHFlux

NASA Technical Reports Server (NTRS)

Wilber, Anne C.; Stackhouse, Paul W., Jr.; Kratz, David P.; Gupta, Shashi K.; Sawaengphokhai, Parnchai K.

2015-01-01

The Fast Longwave and Shortwave Radiative Flux (FLASHFlux) data product was developed to provide a rapid release version of the Clouds and Earth's Radiant Energy System (CERES) results, which could be made available to the research and applications communities within one week of the satellite observations by exchanging some accuracy for speed of processing. Unlike standard CERES products, FLASHFlux does not maintain a long-term consistent record. Therefore the latest algorithm changes and input data can be incorporated into processing. FLASHFlux released Version3A (January 2013) and Version 3B (August 2014) which include the latest meteorological product from Global Modeling and Assimilation Office (GMAO), GEOS FP-IT (5.9.1), the latest spectral response functions and gains for the CERES instruments, and aerosol climatology based on the latest MATCH data. Version 3B included a slightly updated calibration and some changes to the surface albedo over snow/ice. Typically FLASHFlux does not reprocess earlier versions when a new version is released. The combined record of Time Interpolated Space Averaged (TISA) surface flux results from Versions3A and 3B for July 2012 to October 2015 have been compared to the ground-based measurements. The FLASHFlux results are also compared to two other CERES gridded products, SYN1deg and EBAF surface fluxes.

Latest results and perspectives of the KASCADE-Grande EAS Facility

NASA Astrophysics Data System (ADS)

Haungs, A.; Apel, W. D.; Arteaga-Velázquez, J. C.; Bekk, K.; Bertaina, M.; Blümer, J.; Bozdog, H.; Brancus, I. M.; Buchholz, P.; Cantoni, E.; Chiavassa, A.; Cossavella, F.; Daumiller, K.; de Souza, V.; di Pierro, F.; Doll, P.; Engel, R.; Engler, J.; Finger, M.; Fuhrmann, D.; Ghia, P. L.; Gils, H. J.; Glasstetter, R.; Grupen, C.; Heck, D.; Hörandel, J. R.; Huege, T.; Isar, P. G.; Kampert, K.-H.; Kang, D.; Kickelbick, D.; Klages, H. O.; Link, K.; Łuczak, P.; Ludwig, M.; Mathes, H. J.; Mayer, H. J.; Melissas, M.; Milke, J.; Mitrica, B.; Morello, C.; Navarra, G.; Nehls, S.; Oehlschläger, J.; Ostapchenko, S.; Over, S.; Palmieri, N.; Petcu, M.; Pierog, T.; Rebel, H.; Roth, M.; Schieler, H.; Schröder, F. G.; Sima, O.; Toma, G.; Trinchero, G. C.; Ulrich, H.; Weindl, A.; Wochele, J.; Wommer, M.; Zabierowski, J.

2012-01-01

KASCADE-Grande is a multi-detector experiment at KIT (Karlsruhe Institute of Technology) in Germany for measuring extensive air showers in the primary energy range of 100 TeV to 1 EeV. This paper does not provide a synopsis of all results of the KASCADE-Grande experiment. Rather it is focused on three aspects of current interests illustrating the advantages of a multi-detector facility. Results on the analysis of individual energy spectra of primary mass groups around the knee obtained by unfolding the shower size measurements of KASCADE with the help of the new hadronic interaction model EPOS and the all-particle energy spectrum at higher energies obtained by Grande measurements will be discussed. As KASCADE-Grande serves also as host of the LOPES radio detection experiment where both experiments measure the same showers, special emphasis will be given in comparing the characteristics and feasibility of both techniques in estimating the main parameters of high-energy primary cosmic rays: energy, composition, and arrival direction.

School Issues Under [Section] 504 and the ADA: The Latest and Greatest.

ERIC Educational Resources Information Center

Aleman, Steven R.

This paper highlights recent guidance and rulings from the Office of Civil Rights (OCR) of interest to administrators, advocates, and attorneys. It is a companion piece to Student Issues on SectionNB504/ADA: The Latest and Greatest. Compliance with SectionNB504 and the Americans with Disabilities Act (ADA) continues to involve debate and dialog on…

Different regions of latest electrical activation during left bundle-branch block and right ventricular pacing in cardiac resynchronization therapy patients determined by coronary venous electro-anatomic mapping.

PubMed

Mafi Rad, Masih; Blaauw, Yuri; Dinh, Trang; Pison, Laurent; Crijns, Harry J; Prinzen, Frits W; Vernooy, Kevin

2014-11-01

Current targeted left ventricular (LV) lead placement strategy is directed at the latest activated region during intrinsic activation. However, cardiac resynchronization therapy (CRT) is most commonly applied by simultaneous LV and right ventricular (RV) pacing without contribution from intrinsic conduction. Therefore, targeting the LV lead to the latest activated region during RV pacing might be more appropriate. We investigated the difference in LV electrical activation sequence between left bundle-branch block (LBBB) and RV apex (RVA) pacing using coronary venous electro-anatomic mapping (EAM). Twenty consecutive CRT candidates with LBBB underwent intra-procedural coronary venous EAM during intrinsic activation and RVA pacing using EnSite NavX. Left ventricular lead placement was aimed at the latest activated region during LBBB according to current recommendations. In all patients, LBBB was associated with a circumferential LV activation pattern, whereas RVA pacing resulted in activation from the apex of the heart to the base. In 10 of 20 patients, RVA pacing shifted the latest activated region relative to LBBB. In 18 of 20 patients, the LV lead was successfully positioned in the latest activated region during LBBB. For the whole study population, LV lead electrical delay, expressed as percentage of QRS duration, was significantly shorter during RVA pacing than during LBBB (72 ± 13 vs. 82 ± 5%, P = 0.035). Right ventricular apex pacing alters LV electrical activation pattern in CRT patients with LBBB, and shifts the latest activated region in a significant proportion of these patients. These findings warrant reconsideration of the current practice of LV lead targeting for CRT. © 2014 The Authors. European Journal of Heart Failure © 2014 European Society of Cardiology.

The Atmospheric Chemistry Experiment (ACE): Status and Latest Results

NASA Astrophysics Data System (ADS)

Bernath, P. F.; Boone, C. D.; McElroy, C. T.

2017-12-01

ACE (also known as SCISAT) is making a comprehensive set of simultaneous measurements of numerous trace gases, thin clouds, aerosols and temperature by solar occultation from a satellite in low earth orbit. A high inclination (74°) orbit gives ACE coverage of tropical, mid-latitudes and polar regions. The primary instrument is a high-resolution (0.02 cm-1) infrared Fourier Transform Spectrometer (FTS) operating in the 750-4400 cm-1 region, which provides the vertical distribution of trace gases, and the meteorological variables of temperature and pressure. A second instrument, a dual spectrophotometer called MAESTRO, extends the wavelength coverage to the 400-1000 nm spectral region. Aerosols and clouds are being monitored through the extinction of solar radiation using two filtered imagers and by MAESTRO as well as by their infrared spectra. After 14 years in orbit, the ACE is still operating well. A short overview of the ACE mission will be presented (see http://www.ace.uwaterloo.ca for more information). The current version (v. 3.5/3.6) of ACE-FTS processing includes more than 30 molecules and twenty isotopologues; v.3.5/3.6 is now available in near-real time. This talk will focus on recent ACE results and the new version 4.0 of ACE-FTS processing.

Get Up to Speed on the Latest Product Releases in the Education Market

ERIC Educational Resources Information Center

Technology & Learning, 2007

2007-01-01

This article provides brief descriptions of the latest product releases in the education market. These products include hardware, software, and resources. The following products are presented in this article, but not limited to: (1) Radius Audio Learning System(www.learningresources.com); (2) The Indigo Learning System from LearningSoft, LLC…

Air Pollution and Neuropsychological Development: A Review of the Latest Evidence

PubMed Central

Suades-González, Elisabet; Gascon, Mireia; Guxens, Mònica

2015-01-01

For the last decade, literature on the detrimental impacts of air pollution on brain, cognition and behavior has exponentially increased. Our aim is to review the latest epidemiologic literature on the association between outdoor air pollution and neuropsychological developmental in children. Two independent researchers searched for published studies between January 1, 2012 and June 12, 2015 in MEDLINE, Web of Science, and Science direct using defined keywords on outdoor air pollution and neuropsychological development. Selection of articles was based on study eligibility criteria. We encountered sufficient evidence of detrimental effects of pre- or postnatal exposure to polycyclic aromatic hydrocarbons on global intelligence quotient. The evidence was also sufficient for the association between pre- or postnatal exposure to fine particulate matter (PM2.5) and autism spectrum disorder, and limited evidence was encountered between nitrogen oxides and autism spectrum disorder. For other exposure-outcome associations reviewed, the evidence was inadequate or insufficient. Although evidence is not yet conclusive and further research is needed, the latest epidemiological studies support the hypothesis that pre- or postnatal exposure to ambient pollution, particularly polycyclic aromatic hydrocarbons, PM2.5, and nitrogen oxides has a negative impact on the neuropsychological development of children. The public health impact of air pollutants cannot be ignored and the precautionary principle should be applied to protect children. PMID:26241071

Air Pollution and Neuropsychological Development: A Review of the Latest Evidence.

PubMed

Suades-González, Elisabet; Gascon, Mireia; Guxens, Mònica; Sunyer, Jordi

2015-10-01

For the last decade, literature on the detrimental impacts of air pollution on brain, cognition and behavior has exponentially increased. Our aim is to review the latest epidemiologic literature on the association between outdoor air pollution and neuropsychological developmental in children. Two independent researchers searched for published studies between January 1, 2012 and June 12, 2015 in MEDLINE, Web of Science, and Science direct using defined keywords on outdoor air pollution and neuropsychological development. Selection of articles was based on study eligibility criteria. We encountered sufficient evidence of detrimental effects of pre- or postnatal exposure to polycyclic aromatic hydrocarbons on global intelligence quotient. The evidence was also sufficient for the association between pre- or postnatal exposure to fine particulate matter (PM2.5) and autism spectrum disorder, and limited evidence was encountered between nitrogen oxides and autism spectrum disorder. For other exposure-outcome associations reviewed, the evidence was inadequate or insufficient. Although evidence is not yet conclusive and further research is needed, the latest epidemiological studies support the hypothesis that pre- or postnatal exposure to ambient pollution, particularly polycyclic aromatic hydrocarbons, PM2.5, and nitrogen oxides has a negative impact on the neuropsychological development of children. The public health impact of air pollutants cannot be ignored and the precautionary principle should be applied to protect children.

Heavy Ion Microbeam- and Broadbeam-Induced Current Transients in SiGe HBTs

NASA Technical Reports Server (NTRS)

Pellish, Jonathan A.; Reed, R. A.; McMorrow, D.; Vizkelethy, G.; Ferlet-Cavrois, V.; Baggio, J.; Duhamel, O.; Moen, K. A.; Phillips, S. D.; Diestelhorst, R. M.;

Multiple episodes of extensive marine anoxia linked to global warming and continental weathering following the latest Permian mass extinction.

PubMed

Zhang, Feifei; Romaniello, Stephen J; Algeo, Thomas J; Lau, Kimberly V; Clapham, Matthew E; Richoz, Sylvain; Herrmann, Achim D; Smith, Harrison; Horacek, Micha; Anbar, Ariel D

2018-04-01

Explaining the ~5-million-year delay in marine biotic recovery following the latest Permian mass extinction, the largest biotic crisis of the Phanerozoic, is a fundamental challenge for both geological and biological sciences. Ocean redox perturbations may have played a critical role in this delayed recovery. However, the lack of quantitative constraints on the details of Early Triassic oceanic anoxia (for example, time, duration, and extent) leaves the links between oceanic conditions and the delayed biotic recovery ambiguous. We report high-resolution U-isotope (δ 238 U) data from carbonates of the uppermost Permian to lowermost Middle Triassic Zal section (Iran) to characterize the timing and global extent of ocean redox variation during the Early Triassic. Our δ 238 U record reveals multiple negative shifts during the Early Triassic. Isotope mass-balance modeling suggests that the global area of anoxic seafloor expanded substantially in the Early Triassic, peaking during the latest Permian to mid-Griesbachian, the late Griesbachian to mid-Dienerian, the Smithian-Spathian transition, and the Early/Middle Triassic transition. Comparisons of the U-, C-, and Sr-isotope records with a modeled seawater PO 4 3- concentration curve for the Early Triassic suggest that elevated marine productivity and enhanced oceanic stratification were likely the immediate causes of expanded oceanic anoxia. The patterns of redox variation documented by the U-isotope record show a good first-order correspondence to peaks in ammonoid extinctions during the Early Triassic. Our results indicate that multiple oscillations in oceanic anoxia modulated the recovery of marine ecosystems following the latest Permian mass extinction.

Assessing cognitive function in clinical trials: latest developments and future directions.

PubMed

Wesnes, Keith

2002-01-01

Properly developed automated test systems are of value for assessing changes in cognitive function in clinical trials. Besides the other advantages that automation brings to trials, such as increased reliability and utility, it is shown that such systems are also more sensitive to change in cognitive function than traditional nonautomated procedures. Data from a variety of topical areas in drug development are presented to illustrate the added value such techniques have brought. The latest developments in automation include remote testing via the Internet and telephone.

Microscale immobilized enzyme reactors in proteomics: latest developments.

PubMed

Safdar, Muhammad; Spross, Jens; Jänis, Janne

2014-01-10

Enzymatic digestion of proteins is one of the key steps in proteomic analyses. There has been a steady progress in the applied digestion protocols in the past, starting from conventional time-consuming in-solution or in-gel digestion protocols to rapid and efficient methods utilizing different types of microscale enzyme reactors. Application of such microreactors has been proven beneficial due to lower sample consumption, higher sensitivity and straightforward coupling with LC-MS set-ups. Novel stationary phases, immobilization techniques and device formats are being constantly developed and tested to optimize digestion efficiency of proteolytic enzymes. This review focuses on the latest developments associated with the preparation and application of microscale enzyme reactors for proteomics applications since 2008 onwards. A special attention has been paid to the discussion of different stationary phases applied for immobilization purposes. Copyright © 2013 Elsevier B.V. All rights reserved.

A small azhdarchoid pterosaur from the latest Cretaceous, the age of flying giants.

PubMed

Martin-Silverstone, Elizabeth; Witton, Mark P; Arbour, Victoria M; Currie, Philip J

2016-08-01

Pterosaur fossils from the Campanian-Maastrichtian of North America have been reported from the continental interior, but few have been described from the west coast. The first pterosaur from the Campanian Northumberland Formation (Nanaimo Group) of Hornby Island, British Columbia, is represented here by a humerus, dorsal vertebrae (including three fused notarial vertebrae), and other fragments. The elements have features typical of Azhdarchoidea, an identification consistent with dominance of this group in the latest Cretaceous. The new material is significant for its size and ontogenetic stage: the humerus and vertebrae indicate a wingspan of ca 1.5 m, but histological sections and bone fusions indicate the individual was approaching maturity at time of death. Pterosaurs of this size are exceedingly rare in Upper Cretaceous strata, a phenomenon commonly attributed to smaller pterosaurs becoming extinct in the Late Cretaceous as part of a reduction in pterosaur diversity and disparity. The absence of small juveniles of large species-which must have existed-in the fossil record is evidence of a preservational bias against small pterosaurs in the Late Cretaceous, and caution should be applied to any interpretation of latest Cretaceous pterosaur diversity and success.

Latest results on solarization of optical glasses with pulsed laser radiation

NASA Astrophysics Data System (ADS)

Jedamzik, Ralf; Petzold, Uwe

2017-02-01

Femtosecond lasers are more and more used for material processing and lithography. Femtosecond laser help to generate three dimensional structures in photoresists without using masks in micro lithography. This technology is of growing importance for the field of backend lithography or advanced packaging. Optical glasses used for beam shaping and inspection tools need to withstand high laser pulse energies. Femtosecond laser radiation in the near UV wavelength range generates solarization effects in optical glasses. In this paper results are shown of femtosecond laser solarization experiments on a broad range of optical glasses from SCHOTT. The measurements have been performed by the Laser Zentrum Hannover in Germany. The results and their impact are discussed in comparison to traditional HOK-4 and UVA-B solarization measurements of the same materials. The target is to provide material selection guidance to the optical designer of beam shaping lens systems.

Constraints on the unified dark energy dark matter model from latest observational data

NASA Astrophysics Data System (ADS)

Wu, Puxun; Yu, Hongwei

2007-03-01

The generalized Chaplygin gas (GCG) is studied in this paper by using the latest observational data including 182 gold sample type Ia supernovae (Sne Ia) data, the ESSENCE Sne Ia data, the distance ratio from z = 0.35 to 1089 (the redshift of decoupling), the cosmic microwave background shift parameter and the Hubble parameter data. Our results rule out the standard Chaplygin gas model (α = 1) at the 99.7% confidence level, but allow for the λCDM model (α = 0) at the 68.3% confidence level. At a 95.4% confidence level, we obtain w = -0.74-0.09+0.10 and α = -0.14-0.19+0.30. In addition, we find that the phase transition from deceleration to acceleration occurs at redshift zq = 0~0.78-0.89 at a 1σ confidence level for the GCG model.

Latest recanalization techniques for complex superficial femoral artery occlusions.

PubMed

Gonzalez, L; Chen, A; Lin, P H; Pisimisis, G; Barshes, N R; Bechara, C F; Kougias, P

2012-08-01

Complex, long segment lesions of the superficial femoral artery (SFA) are common, occurring in 40% of patients with peripheral vascular disease. In particular, chronic total occlusions (CTOs) continue to pose a challenge in the endovascular management of SFA disease. Several conventional wire and catheter based techniques have been described including subintimal recanalization and retrograde techniques. In addition, advances in endovascular technology have led to the development of a series of new devices aimed specifically at facilitating the crossing of long segment SFA occlusions or establishing re-entry of the true lumen. Here we present an overview of the minimally invasive techniques used to recanalize CTOs of the SFA and the latest specialized devices available for both recanalization and re-entry, as well as a summary of the literature supporting their application.

Multifaceted bench comparative evaluation of latest intensive care unit ventilators.

PubMed

Garnier, M; Quesnel, C; Fulgencio, J-P; Degrain, M; Carteaux, G; Bonnet, F; Similowski, T; Demoule, A

2015-07-01

Independent bench studies using specific ventilation scenarios allow testing of the performance of ventilators in conditions similar to clinical settings. The aims of this study were to determine the accuracy of the latest generation ventilators to deliver chosen parameters in various typical conditions and to provide clinicians with a comprehensive report on their performance. Thirteen modern intensive care unit ventilators were evaluated on the ASL5000 test lung with and without leakage for: (i) accuracy to deliver exact tidal volume (VT) and PEEP in assist-control ventilation (ACV); (ii) performance of trigger and pressurization in pressure support ventilation (PSV); and (iii) quality of non-invasive ventilation algorithms. In ACV, only six ventilators delivered an accurate VT and nine an accurate PEEP. Eleven devices failed to compensate VT and four the PEEP in leakage conditions. Inspiratory delays differed significantly among ventilators in invasive PSV (range 75-149 ms, P=0.03) and non-invasive PSV (range 78-165 ms, P<0.001). The percentage of the ideal curve (concomitantly evaluating the pressurization speed and the levels of pressure reached) also differed significantly (range 57-86% for invasive PSV, P=0.04; and 60-90% for non-invasive PSV, P<0.001). Non-invasive ventilation algorithms efficiently prevented the decrease in pressurization capacities and PEEP levels induced by leaks in, respectively, 10 and 12 out of the 13 ventilators. We observed real heterogeneity of performance amongst the latest generation of intensive care unit ventilators. Although non-invasive ventilation algorithms appear to maintain adequate pressurization efficiently in the case of leakage, basic functions, such as delivered VT in ACV and pressurization in PSV, are often less reliable than the values displayed by the device suggest. © The Author 2015. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions

Late Quaternary Megafaunal Extinctions in Northern Eurasia: Latest Results

NASA Astrophysics Data System (ADS)

Stuart, Anthony

2010-05-01

archaeological records in collaboration with colleagues at Durham University, Royal Holloway, University of London and Southampton University. It is clear from the results that environmental change had a major impact, but the geographical and chronological patterns are complex and there is striking variation in extinction dynamics between species. For example cave bear and spotted hyaena show early extinction in Europe c.28 cal ka, whereas cave lion and woolly rhino disappeared in the Late Glacial c.14 cal ka, and mammoth and giant deer persisted in limited areas well into the Holocene. Our current NERC funded project (3 years from March 2009) extends the scope of our research to include several species that survive to the present day: e.g. musk ox, reindeer, horse, red deer, and moose, and is also extended geographically to Alaska, and the Yukon. Modelling of vegetational changes during the last 40,000 years (by our colleagues at Durham: Judy Allen, Yvonne Collingham, Brian Huntley, using LPJ-Guess data from Paul Valdes) is providing much better geographical coverage than the available pollen data, and also structure and productivity of the vegetation - both of considerable importance to the mammal fauna. Comparing the chronological and geographical dynamics of extant and extinct species promises to shed light on why some species were lost whereas others survived. Moreover, by using a niche-modelling approach we hope to show whether or not species became extinct due to habitat loss, or whether other factors such as human hunting might have been involved in their final disappearance.

Latest aspects of aldosterone actions on the heart muscle.

PubMed

Kritis, A A; Gouta, C P; Liaretidou, E I; Kallaras, K I

2016-02-01

The genomic action of aldosterone has already been known to the scientific community and is well-documented to a satisfactory degree. However, the existence of rapid, non-genomic aldosterone actions has repeatedly been proven. These actions are apparent to a lot of tissues, among which the cardiac tissue, with the cardiac cells being responsible for the secretion of endogenous aldosterone. In the genomic pathway, the connection between the hormone and its receptor results increased reabsorption of sodium and water and excretion of potassium. Thus, the genomic procedure reacts indirectly on cardiovascular system by altering the blood pressure. New studies have shed light on unknown aspects of the non-genomic mechanism, which is sometimes performed by means of mineralocorticoid receptor (MR), while others through an MR-independent pathway. It is believed that aldosterone exerts its non-genomic action with the help of a different receptor, probably a G protein coupled receptor. A possible target is protein kinase C (PKC), and PKCε is postulated increase the permeability of the membrane of the cardiac cells to sodium, resulting in delayed repolarization and prolongation of action potential. These findings totally agree with and account for the serendipitous finding of our laboratory, that there is a positive correlation between plasma aldosterone levels and left ventricle (LV) contraction duration. Also, aldosterone has been proven to exacerbate the oxidative stress and induce vasoconstriction by acting on the vascular resistance and the cardiac output. Finally, this article deals with the role of aldosterone in cardiac fibrosis and the latest aspects of aldosterone actions on the heart muscle as well as providing a historical overview of the landmarks pertaining aldosterone's research.

Improved LCI profile of LAB based on latest technology advances

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berna, J.L.; Renta, C.

1995-12-31

The first technology used to produce LAB was introduced in the early 60`s and since then a continuous optimization process has taken place on this highly competitive product on which additional cost effectiveness improvements became highly challenging. The latest technology introduced in the market (CEPSA {minus} UOP DETAL) based on a fixed bed alkylation process, has already been proved on a commercial scale. The simplicity of the new technology as compared to current ones, namely HF, has proven to be very effective in reducing substantially the impact due to several major components of the Life Cycle Inventory (LCI) in particularmore » the emissions of the overall operation. Additional improvements in other aspects like energy consumption are extremely difficult to achieve today as this parameter has already been highly optimized during the last two decades making in fact LAB a highly effective chemical in terms of energy requirements as well as on raw material consumption. The results of the first LCI of the new LAB technology indicate a reduction of CO process emissions to nearly 1/2 as compared to standard HF process as well as reduction in solid waste to 1/3 of the corresponding HF process. Important reductions have also been noticed on NOx emissions with the new technology.« less

A Gentle Frost: Poet Helen Frost Talks about the Healing Power of Poetry and Her Latest Novel

ERIC Educational Resources Information Center

Margolis, Rick

2006-01-01

This article presents an interview with poet Helen Frost. Frost talked about how poetry can help at-risk children. She also related the challenges she faced when she wrote her latest book titled "The Braid."

Climate Change: The Physical Basis and Latest Results

ScienceCinema

Stocker, Thomas

2018-05-18

The 2007 Assessment Report of the Intergovernmental Panel on Climate Change (IPCC) concludes: "Warming in the climate system is unequivocal." Without the contribution of Physics to climate science over many decades, such a statement would not have been possible. Experimental physics enables us to read climate archives such as polar ice cores and so provides the context for the current changes. For example, today the concentration of CO2 in the atmosphere, the second most important greenhouse gas, is 28% higher than any time during the last 800,000 years. Classical fluid mechanics and numerical mathematics are the basis of climate models from which estimates of future climate change are obtained. But major instabilities and surprises in the Earth System are still unknown. These are also to be considered when the climatic consequences of proposals for geo-engineering are estimated. Only Physics will permit us to further improve our understanding in order to provide the foundation for policy decisions facing the global climate change challenge.

Latest Results of the SETHI Survey at Arecibo

NASA Astrophysics Data System (ADS)

Korpela, E. J.; Demorest, P.; Heien, E.; Heiles, C.; Werthimer, D.

2004-10-01

SETH i is a survey of the distribution of galactic neutral hydrogen being performed comensally at the NAIC Arecibo Observatory. At the same time that observers use receivers in the Gregorian dome, SETHi is recording a 2.5MHz band centered at 1420 MHz from a flat feed on Carriage House 1. During normal astronomical observations, the SETH i feed scans across the sky at twice the sidereal rate. During 4 years of observations, we have accumulated over 15,000 hours of data covering most of the sky accessible to Arecibo. This survey has higher angular resolution than existing single dish surveys and higher sensitivity than existing or planned interferometric surveys.

Relationship between the latest activity of mare volcanism and topographic features of the Moon

NASA Astrophysics Data System (ADS)

Kato, Shinsuke; Morota, Tomokatsu; Yamaguchi, Yasushi; Watanabe, Sei-ichiro; Otake, Hisashi; Ohtake, Makiko

2016-04-01

Lunar mare basalts provide insights into compositions and thermal history of lunar mantle. According to crater counting analysis with remote sensing data, the model ages of mare basalt units indicate a second peak of magma activity at the end of mare volcanism (~2 Ga), and the latest eruptions were limited in the Procellarum KREEP Terrane (PKT), which has high abundances of heat-producing elements. In order to understand the mechanism for causing the second peak and its magma source, we examined the correlation between the titanium contents and eruption ages of mare basalt units using compositional and chronological data updated by SELENE/Kaguya. Although no systematic relationship is observed globally, a rapid increase in mean titanium (Ti) content occurred at 2.3 Ga in the PKT, suggesting that the magma source of mare basalts changed at that time. The high-Ti basaltic eruption, which occurred at the late stage of mare volcanism, can be correlated with the second peak of volcanic activity at ~2 Ga. The latest volcanic activity can be explained by a high-Ti hot plume originated from the core-mantle boundary. If the hot plume was occurred, the topographic features formed by the hot plume may be remained. We calculated the difference between topography and selenoid and found the circular feature like a plateau in the center of the PKT, which scale is ~1000 km horizontal and ~500 m vertical. We investigated the timing of ridge formation in the PKT by using stratigraphic relationship between mare basalts and ridges. The ridges were formed before and after the high-Ti basaltic eruptions and seem to be along with the plateau. These results suggest that the plateau formation is connected with the high-Ti basaltic eruptions.

Latest development of legal regulations of organ transplant in China.

PubMed

Ding, Chunyan

2008-12-01

Organ transplant practice has developed greatly in last two decades in China. In response to the practical need, the State Council released the Regulations on Human Organ Transplant 2007, replacing the previous Interim Provisions on Administration of Clinical Application of Human Organ Transplant Technology 2006. This article first examines the latest development of legal regulations of organ transplant by comparing the differences between the two pieces of legislation. It then analyzes the impact of the new rules set forth in the 2007 Regulations upon three problems existing in the current organ transplant practice, that is, organ procurement from executed prisoners, organ trade, and organ tourism. The article finally discusses the deficiencies of the 2007 Regulations, which are supposed to be remedied in the next legal reform.

[Description of latest generation equipment in external radiotherapy].

PubMed

Pellejero, S; Lozares, S; Mañeru, F

2009-01-01

Both the planning systems and the form of administering radiotherapy have changed radically since the introduction of 3D planning. At present treatment planning based on computerised axial tomography (CAT) images is standard practice in radiotherapy services. In recent years lineal accelerators for medical use have incorporated technology capable of administering intensity modulated radiation beams (IMRT). With this mode distributions of conformed doses are generated that adjust to the three dimensional form of the white volume, providing appropriate coverage and a lower dose to nearby risk organs. The use of IMRT is rapidly spreading amongst radiotherapy centres throughout the world. This growing use of IMRT has focused attention on the need for greater control of the geometric uncertainties in positioning the patient and control of internal movements. To this end, both flat and volumetric image systems have been incorporated into the treatment equipment, making image-guided radiotherapy (IGRT) possible. This article offers a brief description of the latest advances included in the planning and administration of radiotherapy treatment.

[Latest trends and recommendations on epidemiology, diagnosis, and treatment of benign prostatic hyperplasia (BPH)].

PubMed

Gabuev, A; Oelke, M

2011-05-01

A re-evaluation of established tests and treatments has become necessary after publication of several new guidelines on BPH during the past two years. This article describes the latest developments concerning epidemiology, diagnosis, and treatment of BPH. Diagnostic and treatment guidelines on BPH of the German, European, or North American urologists as well as UK doctors were reviewed according to key articles and latest modifications. The only German epidemiological trial on BPH demonstrated that all components of the BPH disease (symptoms - prostate enlargement - bladder outlet obstruction) increase with ageing. 27 % of German men will have disease progression within the next 5 years. Risk factors for disease progression are: age, symptoms, prostate size, PSA, urinary flow rate, and postvoiding residual urine. Diagnosis aims to distinguish BPH from other diseases with similar symptoms, quantify the BPH components, and estimate the individual risk of disease progression. BPH is an exclusion diagnosis. Ultrasonic measurement of detrusor wall thickness at the anterior wall of bladders filled with ≥ 250 mL can securely detect bladder outlet obstruction if the value is ≥ 2 mm. Watchful waiting and lifestyle modifications are suitable for men with mild symptoms and low disease progression risk. All drugs used in BPH treatment reduce symptoms but have no influence on bladder outlet obstruction. α-blockers are first-line drugs and may be combined with muscarinic receptor antagonists or 5α-reductase inhibitors to further increase efficacy. Prostate surgery is indicated when drug treatment is insufficient, the patient develops complications in the upper or lower urinary tract (absolute indications), or has severe bladder outlet obstruction. Standard operations are TURP in small (≤ 80 mL) or open prostatectomy in large prostates (> 80 mL). Minimally invasive, alter-native surgeries may be considered in selected men and -offer advantages with regard to the risk of

Endometriosis: Survey of Current Diagnostic and Therapeutic Options and Latest Research Work

PubMed Central

Juhasz-Böss, I.; Laschke, M. W.; Müller, F.; Rosenbaum, P.; Baum, S.; Solomayer, E. F.; Ulrich, U.

2014-01-01

Endometriosis is one of the most frequent benign diseases in women of child-bearing age. The main symptoms are chronic upper abdominal pain and infertility. However, the aetiology and pathogenesis of endometriosis are as yet insufficiently clarified. Thus, therapy is mainly symptomatic with laparoscopic surgery being the gold standard. The aim of drug therapy is to achieve a hypo-oestrogenic condition. In cases of severe endometriosis and a desire to have children there is often an indication for assisted reproduction. The present article illustrates almost all current aspects on the diagnosis of and therapy of endometriosis. From the clinical viewpoint, emphasis is placed on the rare cases of deeply infiltrating endometriosis that are, however, accompanied with a high morbidity. Current therapeutic options in cases of infertility are also presented in more detail. Furthermore, special attention is paid to the latest research results from both clinical and basic research fields in order to demonstrate our current knowledge on the pathogenesis and, where possible, potentially related therapeutic options. PMID:25221341

[Ten years after the latest revision International Anatomical Terminology].

PubMed

Kachlík, D; Bozdechová, I; Cech, P; Musil, V; Báca, V

2008-01-01

Ten years ago, the latest revision of the Latin anatomical nomenclature was approved and published as Terminologia Anatomica (International Anatomical Terminology), and is acknowledged by the organization uniting national anatomical societies--International Federation of Associations of Anatomists. The authors concentrate on new terms included in the nomenclature and on the linguistic changes of terminology. The most frequent errors done by medical specialists in the usage of the Latin anatomical terminology are emphasized and the situation of eponyms in contemporary anatomy is discussed in detail as well. The last version of the nomenclature makes its way very slowly in the professional community and it is necessary to refer to positive changes and advantages it has brought. The usage of this Latin anatomical nomenclature version is suggested by the International Federation to follow in theoretical and clinical fields of medicine. The authors of the article strongly recommend using the recent revision of the Latin anatomical nomenclature both in the oral and written forms, when educating and publishing.

MCT (HgCdTe) IR detectors: latest developments in France

NASA Astrophysics Data System (ADS)

Reibel, Yann; Rubaldo, Laurent; Vaz, Cedric; Tribolet, Philippe; Baier, Nicolas; Destefanis, Gérard

2010-10-01

This paper presents an overview of the very recent developments of the MCT infrared detector technology developed by CEA-LETI and Sofradir in France. New applications require high sensitivity, higher operating temperature and dual band detectors. The standard n on p technology in production at Sofradir for 25 years is well mastered with an extremely robust and reliable process. Sofradir's interest in p on n technology opens the perspective of reducing dark current of diodes so detectors could operate in lower flux or higher operating temperature. In parallel, MCT Avalanche Photo Diodes (APD) have demonstrated ideal performances for low flux and high speed application like laser gated imaging during the last few years. This technology also opens new prospects on next generation of imaging detectors for compact, low flux and low power applications. Regarding 3rd Gen IR detectors, the development of dual-band infrared detectors has been the core of intense research and technological improvements for the last ten years. New TV (640 x 512 pixels) format MWIR/LWIR detectors on 20μm pixel pitch, made from Molecular Beam Epitaxy, has been developed with dedicated Read-Out Integrated Circuit (ROIC) for real simultaneous detection and maximum SNR. Technological and products achievements, as well as latest results and performances are presented outlining the availability of p/n, avalanche photodiodes and dual band technologies for new applications at system level.

Holocene and latest Pleistocene paleoseismology of the Salt Lake City segment of the Wasatch Fault Zone, Utah, at the Penrose Drive Trench Site

USGS Publications Warehouse

DuRoss, Christopher B.; Hylland, Michael D.; McDonald, Greg N.; Crone, Anthony J.; Personius, Stephen F.; Gold, Ryan D.; Mahan, Shannon

2014-01-01

The Salt Lake City segment (SLCS) of the Wasatch fault zone (WFZ) and the West Valley fault zone (WVFZ) compromise Holocene-active normal faults that bound a large intrabasin graben in northern Salt Lake Valley and have evidence of recurrent, large-magnitude (M ~6-7) surface-faulting earthquakes. However, at the time of this investigation, questions remained regarding the timing, displacement, and recurrence of latest Pleistocene and Holocene earthquakes on the northern SLCS and WVFZ , and whether the WVFZ is seismically independent of, or moves coseismically with, the SLCS. To improve paleoseismic data for the SLCS, we conducted a fault-trench investigation at the Penrose Drive site on the northern SLCS. Two trenches, excavated across an 11-m-high scarp near the northern end of the East Bench fault, exposed colluvial-wedge evidence for fize of six (preferred) surface-faulting earthquakes postdating to Provo-phase shoreline of Lake Bonneville (~14-18 ka). Radiocarbon and luminescence ages support earthquake times at 4.0 ± 0.5 ka (2σ) (PD1), 5.9 ± 0.7 ka (PD2), 7.5 ± 0.8 ka (PD3a), 9.7 ± 1.1 ka (PD3b), 10.9 ± 0.2 ka (PD4), and 12.1 ± 1.6 ka (PD5). At least one additional earthquake occurred at 16.5 ± 1.9 ka (PD6) based on an erosional unconformity that separates deformed Lake Bonneville sily and flat-lying Provo-phase shoreline gravel. Earthquakes PD5-PD1 yield latest Pleistocene (post-Provo) and Holocene mean recurrence intervals of ~1.6 kyr and ~1.7-1.9 kyr, respectively. Using 1.0-1.4 m of per-event vertical displacement for PD5-PD3b corroborate previously identified SLCS earthquakes at 4-10 ka. PD4 and PD5 occurred within an ~8-kyr *17-9 ka) time interval on the SLCS previously interpreted as a period of seismic quiescence, and PD6 possibly corresponds with a previously identified earthquake at ~17 ka (although both events have large timing uncertainties). The Penrose data, when combined with previous paleoseismic results, improve the latest Pleistocene

Reconciling divergent results of the latest parenteral nutrition studies in the ICU.

PubMed

Singer, Pierre; Pichard, Claude

2013-03-01

Recent studies on the optimal modalities to feed patients during the ICU stay show divergent results. The level and the timing of energy provision is a critical issue, associated with the clinical outcome. These results questioned the clinical relevance of the recent guidelines issued by American, Canadian and European academic societies. Four recent prospective randomized studies enrolled critically ill patients who received various nutritional regimens and tested the effect of nutritional support on outcome. The Tight Calorie balance Control Study (TICACOS) targeted on calorie administration according to measured energy expenditure and found increased ICU morbidity but improved hospital mortality. The large EpaNIC study compared 'early' with 'late' (parenteral nutrition) nutrition, mostly in patients after cardiac surgery, and found an increased morbidity associated with early parenteral nutrition. The supplemental parenteral nutrition (SPN) study randomized the patients after 3 days and targeted the calories administered by parenteral nutrition as a complement to unsuccessful enteral nutrition using indirect calorimetry. The SPN resulted in less nosocomial infections and shorter duration of mechanical ventilation. Finally, a recent Australian study enrolled patients unable to be early fed enterally to receive, or not, parenteral nutrition targeted at 1500 kcal. No complications were noted in the parenteral nutrition group. Lessons from all these studies are summarized and should help in designing better studies and guidelines. The critical analysis of recent prospective studies comparing various levels of calorie administration, enteral versus parenteral nutrition and enteral versus SPN confirms the recommendations to avoid underfeeding and overfeeding. Parenteral nutrition, required if enteral feeding is failing, and if adjusted up to a measured optimal level, may improve outcome. More studies on the optimal level of energy and protein administration to

Dry Eye Post-Laser-Assisted In Situ Keratomileusis: Major Review and Latest Updates

PubMed Central

Spierer, Oriel

2018-01-01

Dry eye is one of the most common complications occurring after laser-assisted in situ keratomileusis (LASIK), with virtually all patients experiencing some degree of postoperative dry eye symptoms. Enhanced understanding of the pathophysiology and mechanism of dry eye development in addition to preoperative screening of patients who are prone to dry eye is essential for better patient satisfaction and for improving short-term visual outcome postoperatively. This article reviews the latest studies published on LASIK-associated dry eye, including epidemiology, pathophysiology, risk factors, preoperative assessment, and management. PMID:29619255

A New Saurolophine Dinosaur from the Latest Cretaceous of Far Eastern Russia

PubMed Central

Godefroit, Pascal; Bolotsky, Yuri L.; Lauters, Pascaline

2012-01-01

Background Four main dinosaur sites have been investigated in latest Cretaceous deposits from the Amur/Heilongjiang Region: Jiayin and Wulaga in China (Yuliangze Formation), Blagoveschensk and Kundur in Russia (Udurchukan Formation). More than 90% of the bones discovered in these localities belong to hollow-crested lambeosaurine saurolophids, but flat-headed saurolophines are also represented: Kerberosaurus manakini at Blagoveschensk and Wulagasaurus dongi at Wulaga. Methodology/Principal Findings Herein we describe a new saurolophine dinosaur, Kundurosaurus nagornyi gen. et sp. nov., from the Udurchukan Formation (Maastrichtian) of Kundur, represented by disarticulated cranial and postcranial material. This new taxon is diagnosed by four autapomorphies. Conclusions/Significance A phylogenetic analysis of saurolophines indicates that Kundurosaurus nagornyi is nested within a rather robust clade including Edmontosaurus spp., Saurolophus spp., and Prosaurolophus maximus, possibly as a sister-taxon for Kerberosaurus manakini also from the Udurchukan Formation of Far Eastern Russia. The high diversity and mosaic distribution of Maastrichtian hadrosaurid faunas in the Amur-Heilongjiang region are the result of a complex palaeogeographical history and imply that many independent hadrosaurid lineages dispersed without any problem between western America and eastern Asia at the end of the Cretaceous. PMID:22666331

PubRunner: A light-weight framework for updating text mining results.

PubMed

Anekalla, Kishore R; Courneya, J P; Fiorini, Nicolas; Lever, Jake; Muchow, Michael; Busby, Ben

2017-01-01

Biomedical text mining promises to assist biologists in quickly navigating the combined knowledge in their domain. This would allow improved understanding of the complex interactions within biological systems and faster hypothesis generation. New biomedical research articles are published daily and text mining tools are only as good as the corpus from which they work. Many text mining tools are underused because their results are static and do not reflect the constantly expanding knowledge in the field. In order for biomedical text mining to become an indispensable tool used by researchers, this problem must be addressed. To this end, we present PubRunner, a framework for regularly running text mining tools on the latest publications. PubRunner is lightweight, simple to use, and can be integrated with an existing text mining tool. The workflow involves downloading the latest abstracts from PubMed, executing a user-defined tool, pushing the resulting data to a public FTP or Zenodo dataset, and publicizing the location of these results on the public PubRunner website. We illustrate the use of this tool by re-running the commonly used word2vec tool on the latest PubMed abstracts to generate up-to-date word vector representations for the biomedical domain. This shows a proof of concept that we hope will encourage text mining developers to build tools that truly will aid biologists in exploring the latest publications.

Conceptual DFT Descriptors of Amino Acids with Potential Corrosion Inhibition Properties Calculated with the Latest Minnesota Density Functionals

PubMed Central

Frau, Juan; Glossman-Mitnik, Daniel

2017-01-01

Amino acids and peptides have the potential to perform as corrosion inhibitors. The chemical reactivity descriptors that arise from Conceptual DFT for the twenty natural amino acids have been calculated by using the latest Minnesota family of density functionals. In order to verify the validity of the calculation of the descriptors directly from the HOMO and LUMO, a comparison has been performed with those obtained through ΔSCF results. Moreover, the active sites for nucleophilic and electrophilic attacks have been identified through Fukui function indices, the dual descriptor Δf(r) and the electrophilic and nucleophilic Parr functions. The results could be of interest as a starting point for the study of large peptides where the calculation of the radical cation and anion of each system may be computationally harder and costly. PMID:28361050

Conceptual DFT Descriptors of Amino Acids with Potential Corrosion Inhibition Properties Calculated with the Latest Minnesota Density Functionals.

PubMed

Frau, Juan; Glossman-Mitnik, Daniel

2017-01-01

Amino acids and peptides have the potential to perform as corrosion inhibitors. The chemical reactivity descriptors that arise from Conceptual DFT for the twenty natural amino acids have been calculated by using the latest Minnesota family of density functionals. In order to verify the validity of the calculation of the descriptors directly from the HOMO and LUMO, a comparison has been performed with those obtained through ΔSCF results. Moreover, the active sites for nucleophilic and electrophilic attacks have been identified through Fukui function indices, the dual descriptor Δf( r ) and the electrophilic and nucleophilic Parr functions. The results could be of interest as a starting point for the study of large peptides where the calculation of the radical cation and anion of each system may be computationally harder and costly.

NET-VISA, a Bayesian method next-generation automatic association software. Latest developments and operational assessment.

NASA Astrophysics Data System (ADS)

Le Bras, Ronan; Kushida, Noriyuki; Mialle, Pierrick; Tomuta, Elena; Arora, Nimar

2017-04-01

The Preparatory Commission for the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO) has been developing a Bayesian method and software to perform the key step of automatic association of seismological, hydroacoustic, and infrasound (SHI) parametric data. In our preliminary testing in the CTBTO, NET_VISA shows much better performance than its currently operating automatic association module, with a rate for automatic events matching the analyst-reviewed events increased by 10%, signifying that the percentage of missed events is lowered by 40%. Initial tests involving analysts also showed that the new software will complete the automatic bulletins of the CTBTO by adding previously missed events. Because products by the CTBTO are also widely distributed to its member States as well as throughout the seismological community, the introduction of a new technology must be carried out carefully, and the first step of operational integration is to first use NET-VISA results within the interactive analysts' software so that the analysts can check the robustness of the Bayesian approach. We report on the latest results both on the progress for automatic processing and for the initial introduction of NET-VISA results in the analyst review process

Treatment of diverticular disease: an update on latest evidence and clinical implications.

PubMed

Carabotti, Marilia; Annibale, Bruno

2018-01-01

Diverticular disease (DD) is a common condition, especially in Western countries. In about 80% of patients, colonic diverticula remain asymptomatic (diverticulosis), while approximately 20% of patients may develop abdominal symptoms (symptomatic uncomplicated diverticular disease, SUDD) and, eventually complications as acute diverticulitis (AD). The management of this condition has been improved, and in the last five years European countries and the USA have published guidelines and recommendations. To summarize the latest evidence and clinical implication in treatment of DD focusing the attention either on the treatment of diverticulosis, SUDD and AD together with the primary and secondary prevention of diverticulitis. The present review was based on the latest evidence in the treatment of DD in the last 10 years. In the last 5 years, six countries issued guidelines on DD with differences regarding covered topics and recommendations regarding treatments. At present there is a lack of rationale for drug use in patients with asymptomatic diverticulosis, but there are limited indications to suggest an increase in dietary fibre to reduce risk of DD. To achieve symptomatic relief in SUDD patients, several therapeutic strategies with fibre, probiotics, rifaximin and mesalazine have been proposed even if a standard therapeutic approach remained to be defined. Agreement has been reached for the management of AD, since recent guidelines showed that antibiotics can be used selectively, rather than routinely in uncomplicated AD, although use of antibiotics remained crucial in the management of complicated cases. With regard to treatment for the primary and secondary prevention of AD, the efficacy of rifaximin and mesalazine has been proposed although with discordant recommendations among guidelines. Treatment of DD represented an important challenge in clinical practice, especially concerning management of SUDD and the primary and secondary prevention of AD.

Latest status of El Niño and La Niña

Science.gov Websites

Simplified Chinese El Niño and La Niña Latest status (May 2018) In the past month or so, the warming trend returned to normal in April 2018, indicating that the La Niña event had come to an end. Based on the ±o, La Niña, ENSO? The impact of El Niño and La Niña on the climate of Hong Kong Seasonal and

Examining the cosmic acceleration with the latest Union2 supernova data

NASA Astrophysics Data System (ADS)

Li, Zhengxiang; Wu, Puxun; Yu, Hongwei

2011-01-01

In this Letter, by reconstructing the Om diagnostic and the deceleration parameter q from the latest Union2 Type Ia Supernova sample with and without the systematic error along with the baryon acoustic oscillation (BAO) and the cosmic microwave background (CMB), we study the cosmic expanding history, using the Chevallier-Polarski-Linder (CPL) parametrization. We obtain that Union2+BAO favor an expansion with a decreasing of the acceleration at z<0.3. However, once the CMB data is added in the analysis, the cosmic acceleration is found to be still increasing, indicating a tension between low redshift data and high redshift. In order to reduce this tension significantly, two different methods are considered and thus two different subsamples of Union2 are selected. We then find that two different subsamples+BAO+CMB give completely different results on the cosmic expanding history when the systematic error is ignored, with one suggesting a decreasing cosmic acceleration, the other just the opposite, although both of them alone with BAO support that the cosmic acceleration is slowing down. However, once the systematic error is considered, two different subsamples of Union2 along with BAO and CMB all favor an increasing of the present cosmic acceleration. Therefore a clear-cut answer on whether the cosmic acceleration is slowing down calls for more consistent data and more reliable methods to analyze them.

Latest experiences and future plans on NSLS-II insertion devices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tanabe, T.; Hidaka, Y.; Kitegi, C.

National Synchrotron Light Source-II (NSLS-II) is the latest storage ring of 3 GeV energy at the Brookhaven National Laboratory (BNL). The horizontal emittance of the electron beam with the currently installed six damping wigglers is 0.9 nm.rad, which could be further reduced to 0.5 nm.rad with more insertion devices (IDs). With only one RF cavity the beam current is restricted to 200 mA. Five hundred mA operation is envisaged for next year with an addition of the second cavity. Six (plus two branches) beamlines have been commissioned in the initial phase of the project. In July 2015, three NIH fundedmore » beamlines called “Advanced Beamlines for Biological Investigations with X-rays” (ABBIX) will be added for operation. This paper describes the experiences of ID development, installation, and commissioning for the NSLS-II project as well as our future plans to improve the performance of the facility in terms of source development.« less

Vasodilators in Acute Heart Failure: Review of the Latest Studies.

PubMed

Levy, Phillip D; Laribi, Said; Mebazaa, Alexandre

2014-06-01

Vasodilators play an important role in the management of acute heart failure, particularly when increased afterload is the precipitating cause of decompensation. The time-honored approach to afterload reduction has been largely focused on use of intravenous nitrovasodilators and, when properly dosed, this class of agents does provide substantial symptom relief for patients with acute hypertensive heart failure. Despite this, nitrovasodilators have never been shown to diminish mortality or provide any post-discharge outcome benefit leading to an on-going search for viable and more effective alternatives. While no new vasodilators have been approved for use in acute heart failure since nesiritide more than a decade ago, a number of novel agents have been developed, with some showing significant promise in recent clinical trials. In this review, we summarize the latest study data as it relates to vasodilator therapy and provide a glimpse into the not too distant future state of acute heart failure care.

Latest cold fusion results fail to win over skeptics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dagani, R.

1993-06-14

It's been four years since electrochemists Martin Fleischmann and Stanley Pons polarized the scientific community into two camps: those who believe they discovered a new phenomenon, dubbed cold fusion, and those who do not. Now, a new calorimetry paper coauthored by Pons and Fleischmann has dumped fresh fuel on the fire, but it doesn't seem to be changing anyone's mind. The paper in question, titled [open quotes]Calorimetry of the Pd-D[sub 2]O system: from simplicity via complications to simplicity[close quotes], was published in the May 3 issue of Physics Letters. As in their earlier work at the University of Utah, Ponsmore » and Fleischmann, now working in a Japanese-funded laboratory in the south of France, electrolyze heavy water in open cells containing a palladium cathode and a platinum anode. And, as before, they observe the production of high rates of excess enthalpy--more enthalpy (heat content) than was put into the system and more, they say, than can be accounted for by the chemical changes occurring. So much heat is generated, in fact, that the electrolyte (D[sub 2]O and Li[sub 2]SO[sub 4]) eventually begins to boil. This paper describes the continuing controversy.« less

Experiments with neutron-rich isomeric beams

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rykaczewski, K.; Grzywacz, R.; Lewitowicz, M.

1998-01-01

A review of experimental results obtained on microsecond-isomeric states in neutron-rich nuclei produced in fragmentation reactions and studied with SISSI-Alpha-LISE3 spectrometer system at GANIL Caen is given. The perspectives of experiments based on secondary reactions with isomeric beams are presented.

A latest developed all permanent magnet ECRIS for atomic physics research at IMP

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sun, L.T.; Zhao, H.W.; Zhang, Z.M.

2006-03-15

Electron cyclotron resonance (ECR) ion sources have been used for atomic physics research for a long time. With the development of atomic physics research in the Institute of Modern Physics (IMP), additional high performance experimental facilities are required. A 300 kV high voltage (HV) platform has been under construction since 2003, and an all permanent magnet ECR ion source is supposed to be put on the platform. Lanzhou all permanent magnet ECR ion source No. 2 (LAPECR2) is a latest developed all permanent magnet ECRIS. It is a 900 kg weight and null-set 650 mmx562 mm outer dimension (magnetic body)more » ion source. The injection magnetic field of the source is 1.28 T and the extraction magnetic field is 1.07 T. This source is designed to be running at 14.5 GHz. The high magnetic field inside the plasma chamber enables the source to give good performances at 14.5 GHz. LAPECR2 source is now under commissioning in IMP. In this article, the typical parameters of the source LAPECR2 are listed, and the typical results of the preliminary commissioning are presented.« less

Performance, optimization, and latest development of the SRI family of rotary cryocoolers

NASA Astrophysics Data System (ADS)

Dovrtel, Klemen; Megušar, Franc

2017-05-01

In this paper the SRI family of Le-tehnika rotary cryocoolers is presented (SRI401, SRI423/SRI421 and SRI474). The Stirling coolers cooling power range starts from 0.25W to 0.75W at 77K with available temperature range from 60K to 150K and are fitted to typical dewar detector sizes and powers supply voltages. The DDCA performance optimizing procedure is presented. The procedure includes cooler steady state performance mapping and optimization and cooldown optimization. The current cryogenic performance status and reliability evaluation method and figures are presented on the existing and new units. The latest improved SRI401 demonstrated MTTF close to 25'000 hours and the test is still on going.

Latest results of 5-ALA-based fluorescence diagnosis and other medical disciplines

NASA Astrophysics Data System (ADS)

Baumgartner, Reinhold

1999-02-01

Preclinical and clinical studies on 5-aminolevulinic acid (5- ALA) induced Protoporphyrin IX (PPIX) are performed in various departments now following promising clinical results for the detection of bladder cancer in urology. This paper provides an overview on the progress of 5-ALA assisted fluorescence diagnosis in urology, pulmonology, neurosurgery, gynecology and ENT coordinated by the Laser Research Laboratory of the Ludwig-Maximilians-University in Munich. 5-ALA can be applied either topically or systematically to induce an intracellular accumulation of fluorescing PPIX. With appropriate dosage of 5-ALA, malignant tissue can be stained selectively, and irradiation with violet light excites a bright red fluorescence of the tumor visible with naked eyes. Optical properties of the tissue tend to hamper the precise identification and demarcation of suspect areas in fluorescence images. Multicolor remission and fluorescence imaging, therefore, should improve tumor localization in future.

Latest astronomical constraints on some non-linear parametric dark energy models

NASA Astrophysics Data System (ADS)

Yang, Weiqiang; Pan, Supriya; Paliathanasis, Andronikos

2018-04-01

We consider non-linear redshift-dependent equation of state parameters as dark energy models in a spatially flat Friedmann-Lemaître-Robertson-Walker universe. To depict the expansion history of the universe in such cosmological scenarios, we take into account the large-scale behaviour of such parametric models and fit them using a set of latest observational data with distinct origin that includes cosmic microwave background radiation, Supernove Type Ia, baryon acoustic oscillations, redshift space distortion, weak gravitational lensing, Hubble parameter measurements from cosmic chronometers, and finally the local Hubble constant from Hubble space telescope. The fitting technique avails the publicly available code Cosmological Monte Carlo (COSMOMC), to extract the cosmological information out of these parametric dark energy models. From our analysis, it follows that those models could describe the late time accelerating phase of the universe, while they are distinguished from the Λ-cosmology.

Latest generation of flat detector CT as a peri-interventional diagnostic tool: a comparative study with multidetector CT.

PubMed

Leyhe, Johanna Rosemarie; Tsogkas, Ioannis; Hesse, Amélie Carolina; Behme, Daniel; Schregel, Katharina; Papageorgiou, Ismini; Liman, Jan; Knauth, Michael; Psychogios, Marios-Nikos

2017-12-01

Flat detector CT (FDCT) has been used as a peri-interventional diagnostic tool in numerous studies with mixed results regarding image quality and detection of intracranial lesions. We compared the diagnostic aspects of the latest generation FDCT with standard multidetector CT (MDCT). 102 patients were included in our retrospective study. All patients had undergone interventional procedures. FDCT was acquired peri-interventionally and compared with postinterventional MDCT regarding depiction of ventricular/subarachnoidal spaces, detection of intracranial hemorrhage, and delineation of ischemic lesions using an ordinal scale. Ischemic lesions were quantified with the Alberta Stroke Program Early CT Scale (ASPECTS) on both examinations. Two neuroradiologists with varying grades of experience and a medical student scored the anonymized images separately, blinded to the clinical history. The two methods were of equal diagnostic value regarding evaluation of the ventricular system and the subarachnoidal spaces. Subarachnoidal, intraventricular, and parenchymal hemorrhages were detected with a sensitivity of 95%, 97%, and 100% and specificity of 97%, 100%, and 99%, respectively, using FDCT. Gray-white differentiation was feasible in the majority of FDCT scans, and ischemic lesions were detected with a sensitivity of 71% on FDCT, compared with MDCT scans. The mean difference in ASPECTS values on FDCT and MDCT was 0.5 points (95% CI 0.12 to 0.88). The latest generation of FDCT is a reliable and accurate tool for the detection of intracranial hemorrhage. Gray-white differentiation is feasible in the supratentorial region. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Clonal evolution of acute myeloid leukemia highlighted by latest genome sequencing studies.

PubMed

Zhang, Xuehong; Lv, Dekang; Zhang, Yu; Liu, Quentin; Li, Zhiguang

2016-09-06

Decades of years might be required for an initiated cell to become a fully-pledged, metastasized tumor. DNA mutations are accumulated during this process including background mutations that emerge scholastically, as well as driver mutations that selectively occur in a handful of cancer genes and confer the cell a growth advantage over its neighbors. A clone of tumor cells could be superseded by another clone that acquires new mutations and grows more aggressively. Tumor evolutional patterns have been studied for years using conventional approaches that focus on the investigation of a single or a couple of genes. Latest deep sequencing technology enables a global view of tumor evolution by deciphering almost all genome aberrations in a tumor. Tumor clones and the fate of each clone during tumor evolution can be depicted with the help of the concept of variant allele frequency. Here, we summarize the new insights of cancer evolutional progression in acute myeloid leukemia. Cancer evolution is currently thought to start from a clone that has accumulated the requisite somatically-acquired genetic aberrations through a series of increasingly disordered clinical and pathological phases, eventually leading to malignant transformation [1-3]. The observations in invasive colorectal cancer that usually emerges from an antecedent benign adenomatous polyp and in cervical cancer that proceeds through intraepithelial neoplasia support the idea of stepwise or linear cancerous progression [3-5]. Genetically, such progression is achieved by successive waves of clonal expansion during which cells acquire novel genomic alterations including single nucleotide variants (SNVs), small insertions and deletions (indels), and/or copy number variations (CNVs) [6]. The latest improvement in sequencing technology has allowed the deciphering of the whole exome or genome in different types of tumor and normal tissue pairs, providing detailed catalogue about genome aberrations during tumor

University Satellite Featuring Latest OBC Core & Payload Data Processing Technologies

NASA Astrophysics Data System (ADS)

Eickhoff, Jens; Roser, Hans-Peter; Stevenson, Dave; Habinc, Sandi

2010-08-01

As already published in diverse papers, University of Stuttgart, Germany, is running a small satellite development programme. The first satellite under development (Phase C) is a 3-axis stabilized LEO satellite with a box size of 60cm x 70cm x 80cm, deployable solar panels, ACS including star trackers, wheels and GPS and a mass of 120kg. Launch is envisaged 2013 on an ISRO PSLV launcher. The design is conceptualized to be suitable not only for this specific mission, but to serve as Future Lowcost Platform for diverse science smallsat missions. This paper presents the latest onboard computer technologies selected and defined for the spacecraft covering both the main OBC (CDMU) as well as the payload data processing unit (PMC). The key point is that although being a university project it has been achieved to implement onboard hardware and software design to be fully compliant to international space standards like CCSDS and PUS. The corresponding author is system engineering coach for the project from industry.

Estimating Latest Cretaceous and Tertiary Atmospheric PCO2 from Stomatal Indices

NASA Astrophysics Data System (ADS)

Royer, D. L.; Wing, S. L.; Beerling, D. J.

2001-05-01

Most modern C3 seed plants show an inverse relationship between PCO2 and stomatal index (SI), where SI is the proportion of epidermal cells that are stomatal packages. This plant-atmosphere response therefore provides a reliable approach for estimating paleo-CO2 levels. Since stomatal responses to CO2 are generally species-specific, one is limited in paleo-reconstructions to species that exist both in the fossil record and living today. Fossils morphologically similar to living Ginkgo biloba and Metasequoia glyptostroboides extend back to the early and late Cretaceous, respectively, indicating that the fossil and living forms are very closely related. Measurements of SI made on fossil Ginkgo and Metasequoia were calibrated with historical collections of G. biloba and M. glyptostroboides leaves from sites that developed during the anthropogenically-driven CO2 increases of the past 145 years (288-369 ppmv) and with saplings of G. biloba and M. glyptostroboides grown in CO2 controlled growth chambers (350-800 ppmv). Both nonlinear regressions are highly significant (Ginkgo: n = 40, r2 = 0.91; Metasequoia: n = 18; r2 = 0.85). Results from a sequence of 23 latest Cretaceous to early Eocene-aged Ginkgo-bearing sites indicate that CO2 remained between 300 and 450 ppmv with the exception of one high estimate ( ~800 ppmv) near the Paleocene/Eocene boundary, and results from 4 middle Miocene-aged Ginkgo- and Metasequoia-bearing sites indicate that CO2 was between 320 and 400 ppmv. If correct, the CO2 values estimated here are too low to explain via the CO2 greenhouse effect alone the higher global mean temperatures (e.g., 3-4 ° C for the early Eocene) inferred from models and geological data for these two intervals.

Improvement in conformability of the latest generation of thoracic stent grafts.

PubMed

Canaud, Ludovic; Cathala, Philipe; Joyeux, Frédéric; Branchereau, Pascal; Marty-Ané, Charles; Alric, Pierre

2013-04-01

Poor aortic arch apposition increases the risk of technical failure after thoracic endovascular repair. The aim of this study was to assess the conformability of the latest generation of thoracic stent grafts in relation to the degree of device oversizing and aortic arch angulation. A benchtop pulsatile flow model was designed to test stent graft anchorage in a 2-cm-long proximal landing zone at varying landing zone angles (from 140° down to 70°) and stent graft oversizing (12%-28%). The experiments were performed using 10 human thoracic cadaveric aortas and four stent grafts: C-TAG, Zenith TX2 Pro-Form, Valiant Captivia, and Relay. Device-wall apposition was measured as a function of landing zone angulation and oversizing during static and dynamic (60 pulses/min, 300/150 mm Hg) tests. The Valiant stent graft remained apposed to the aortic wall at each increment of neck angulation and device oversizing. Lack of apposition of the proximal anchorage segment was observed with the C-TAG above 120° landing zone angulation (1-2 mm) and with the Relay above 110° landing zone angulation (1-4 mm). Lack of "body" apposition (1-4 mm) was first observed with the Zenith Pro-Form stent graft above 110° angulation (P = .001). When the device was not apposed to the aortic wall, an increase in stent graft oversizing significantly (P = .01) decreased device-wall apposition. The requirement for close conformability has influenced the design of next-generation devices. Manufacturers have modified devices and/or their deployment system to specifically address this problem. When compared with the results of our previous experimental test, this study demonstrates that these alterations have resulted in a marked improvement in the performance of commercially available stent graft systems. Copyright © 2013 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.

Influence of radiotherapy on the latest generation of implantable cardioverter-defibrillators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hurkmans, Coen W.; Scheepers, Egon; Springorum, Bob G.F.

2005-09-01

Purpose: Radiotherapy can influence the functioning of pacemakers and implantable cardioverter-defibrillators (ICDs). ICDs offer the same functionality as pacemakers, but are also able to deliver a high-voltage shock to the heart if needed. Guidelines for radiotherapy treatment of patients with an implanted rhythm device have been published in 1994 by The American Association of Physicists in Medicine, and are based only on experience with pacemakers. Data on the influence of radiotherapy on ICDs are limited. The objective of our study is to determine the influence of radiotherapy on the latest generation of ICDs. Methods and Materials: Eleven modern ICDs havemore » been irradiated in our department. The irradiation was performed with a 6-MV photon beam. The given dose was fractionated up to a cumulative dose of 120 Gy. Two to 5 days passed between consecutive irradiations. Frequency, output, sensing, telemetry, and shock energy were monitored. Results: Sensing interference by ionizing radiation on all ICDs has been demonstrated. For four ICDs, this would have caused the inappropriate delivery of a shock because of interference. At the end of the irradiation sessions, all devices had reached their point of failure. Complete loss of function was observed for four ICDs at dose levels between 0.5 Gy and 1.5 Gy. Conclusions: The effect of radiation therapy on the newest generation of ICDs varies widely. If tachycardia monitoring and therapy are functional (programmed on) during irradiation, the ICD might inappropriately give antitachycardia therapy, often resulting in a shock. Although most ICDs did not fail below 80 Gy, some devices had already failed at doses below 1.5 Gy. Guidelines are formulated for the treatment of patients with an ICD.« less

Intellectual Engagement, Good Grades and "Doing School": Latest Reports from CEA's What Did You Do in School Today? Initiative

ERIC Educational Resources Information Center

Sefcik, Michael

2013-01-01

Are students just "doing school" or are they engaged with their studies? How does a student's level of engagement influence learning, achievement, and teaching? The latest series of What did you do in school today? reports focus on academic outcomes, instructional challenge, and intellectual engagement. The reports reveal there is a…

FUSTIPEN—the France-U.S. Theory Institute for Physics with Exotic Nuclei

DOE Office of Scientific and Technical Information (OSTI.GOV)

Papenbrock, Thomas

FUSTIPEN, the France-U.S. Theory Institute for Physics with Exotic Nuclei, was an international venue for theoretical research on the physics of nuclei during an era of particularly active experimental investigations of rare isotopes, see http://fustipen.ganil.fr/. It was dedicated to collaborative research between U.S.-based and French nuclear physicists, drawing on the complementary expertise in the two countries. The grant provided travel and local support for visits by U.S. nuclear physicists to GANIL, where the FUSTIPEN offices are located, and also supported collateral travel to other French research institutions.

Peripartum management of bipolar disorder: what do the latest guidelines recommend?

PubMed

Sharma, Verinder; Sharma, Sapna

2017-04-01

Many women with bipolar disorder experience significant morbidity during pregnancy and the postpartum period. The use of evidence-based and up-to-date guidelines has the potential to improve maternal and neonatal care. We review the latest clinical practice guidelines to gather recommendations for the peripartum management of bipolar disorder. Areas covered: Three electronic databases, MEDLINE/PubMed, the Cochrane Library, and the National Guidelines Clearinghouse were searched using various combinations of the following terms: bipolar disorder, pregnancy, postpartum, peripartum, puerperal, antenatal, postnatal, and guidelines. All guidelines retrieved were published, revised, or reaffirmed during the period from November 2010-June 2016. Expert commentary: To date there are no exclusive guidelines for the peripartum management of bipolar disorder. Currently available guidelines do not provide sufficient guidance for clinicians to deliver optimal care to women before, during, and after pregnancy. The guidelines reflect the paucity of available literature on the peripartum management of bipolar disorder. Further research is urgently needed to strengthen the evidence supporting the guidelines recommendations.

Recent Results of the Telescope Array Experiment

NASA Astrophysics Data System (ADS)

Ivanov, Dmitri

2015-04-01

The Telescope Array (TA) is the largest cosmic ray experiment in the northern hemisphere and covers 10 PeV to 100 EeV range. TA is a hybrid detector that uses air fluorescence detectors combined with a ground array. TA consists of 507 plastic scintillation counters on a 1.2km square grid, overlooked by 3 fluorescence detector stations, and measures cosmic rays above 1 EeV. TA has collected 6.5 years of data. Results from the TA low energy extension (TALE), which sees cosmic rays down to 10 PeV, will also be shown. This contribution will consist of three parts. First, we will present the cosmic ray energy spectrum measured over 4 decades in energy. Next, we will discuss the latest results of the measurements of cosmic ray mass composition by the TA fluorescence detectors. Finally, we will show the latest results of the TA anisotropy measurements at the highest energies, where we have seen a concentration of events, called the ``hotspot,'' centered in the Ursa Major. For the Telescope Array Collaboration. Done...processed 1261 records...10:46:59 Beginning APS data extraction...10:47:48

Paleoecological implications of Alaskan terrestrial vertebrate fauna in latest Cretaceous time at high paleolatitudes

NASA Astrophysics Data System (ADS)

Clemens, William A.; Gayle Nelms, L.

1993-06-01

The latest Cretaceous cool temperate environment of the Alaskan North Slope included dinosaurs (some species represented by both juveniles and adults) and mammals, all probably endothermic, and freshwater fish among its terrestrial vertebrate fauna. No traces have been found of amphibians or nondinosaurian reptiles, ectothermic vertebrates that are abundantly represented in approximately contemporaneous faunas of North American middle paleolatitudes. A geologically brief period of intense cold and darkness has been hypothesized as the primary cause of terminal Cretaceous extinctions. However, the extinction of the lineages of Alaskan dinosaurs and mammals, in contrast to the survival of most lineages of amphibians and nondinosaurian reptiles into the Tertiary, contradicts this hypothesis.

Mass spectrometric profiling of low-molecular-weight volatile compounds--diagnostic potential and latest applications.

PubMed

Lechner, Matthias; Rieder, Josef

2007-01-01

The theoretical use of mass spectrometric profiling of low-molecular-weight volatile compounds, as one possible method to non-invasively and rapidly diagnose a variety of diseases, such as cancer, infection, and metabolic disorders has greatly raised the profile of this technique over the last ten years. Despite a number of promising results, this technique has not been introduced into common clinical practice yet. The use of mass spectrometric profiling of exhaled air is particularly hampered by various technical problems and basic methodological issues which have only been partially overcome. However, breath analysis aside, recently published studies reveal completely new ideas and concepts on how to establish fast and reliable diagnosis by using this valuable tool. These studies focussed on the headspace screening of various bodily fluids and sample fluids obtained during diagnostic procedures, as well as microbial cell cultures and demonstrated the vast diagnostic potential of this technique in a wide variety of settings, predominantly in vitro. It is the aim of the present review to discuss the most commonly detected low-molecular-weight volatile compounds and to summarize the current potential applications, latest developments and future perspectives of this promising diagnostic approach.

Repeat transcatheter aortic valve implantation using a latest generation balloon-expandable device for treatment of failing transcatheter heart valves.

PubMed

Schaefer, Andreas; Treede, Hendrik; Seiffert, Moritz; Deuschl, Florian; Schofer, Niklas; Schneeberger, Yvonne; Blankenberg, Stefan; Reichenspurner, Hermann; Schaefer, Ulrich; Conradi, Lenard

2016-01-15

Paravalvular leakage (PVL) is a known complication of transcatheter aortic valve implantation (TAVI) and is associated with poor outcome. Besides balloon-post-dilatation, valve-in-valve (ViV) procedures can be taken into consideration to control this complication. Herein we present initial experience with use of the latest generation balloon-expandable Edwards Sapien 3® (S3) transcatheter heart valve (THV) for treatment of failing THVs. Between 01/2014 and 12/2014 three patients (two male, age: 71-80 y, log EUROScore I: 11.89 - 32.63) with failing THVs were refered to our institution for further treatment. THV approach with secondary implantation of an S3 was chosen after mutual agreement of the local interdisciplinary heart team at an interval of 533-1119 days from the index procedure. The performed procedures consisted of: S3 in Sapien XT, JenaValve and CoreValve. Successful transfemoral implantation with significant reduction of PVL was achieved in all cases. No intraprocedural complications occurred regarding placement of the S3 with a postprocedural effective orifice area (EOA) of 1.5-2.5 cm(2) and pressure gradients of max/mean 14/6-36/16 mmHg. 30-day mortality was 0%. At the latest follow-up of 90-530 days, all patients are alive and well with satisfactory THV function. Regarding VARC-2 criteria one major bleeding and one TIA was reported. In the instance of moderate or severe aortic regurgitation after TAVI, S3 ViV deployment is an excellent option to reduce residual regurgitation to none or mild. For further assertions concerning functional outcomes long-term results have to be awaited.

Heavy flavor results at RHIC - A comparative overview

DOE PAGES

Dong, Xin

2012-01-01

I review the latest heavy flavor measurements at RHIC experiments. Measurements from RHIC together with preliminary results from LHC offer us an opportunity to systematically study the sQGP medium properties. In the end, I will outlook a prospective future on precision heavy flavor measurements with detector upgrades at RHIC.

Status of the ion sources developments for the Spiral2 project at GANILa)

NASA Astrophysics Data System (ADS)

Lehérissier, P.; Bajeat, O.; Barué, C.; Canet, C.; Dubois, M.; Dupuis, M.; Flambard, J. L.; Frigot, R.; Jardin, P.; Leboucher, C.; Lemagnen, F.; Maunoury, L.; Osmond, B.; Pacquet, J. Y.; Pichard, A.; Thuillier, T.; Peaucelle, C.

2012-02-01

The SPIRAL 2 facility is now under construction and will deliver either stable or radioactive ion beams. First tests of nickel beam production have been performed at GANIL with a new version of the large capacity oven, and a calcium beam has been produced on the heavy ion low energy beam transport line of SPIRAL 2, installed at LPSC Grenoble. For the production of radioactive beams, several target/ion-source systems (TISSs) are under development at GANIL as the 2.45 GHz electron cyclotron resonance ion source, the surface ionization source, and the oven prototype for heating the uranium carbide target up to 2000 °C. The existing test bench has been upgraded for these developments and a new one, dedicated for the validation of the TISS before mounting in the production module, is under design. Results and current status of these activities are presented.

Latest approaches on green chemistry preconcentration methods for trace metal determination in seawater--a review.

PubMed

La Colla, Noelia Soledad; Domini, Claudia Elizabeth; Marcovecchio, Jorge Eduardo; Botté, Sandra Elizabeth

2015-03-15

Evaluation of trace metal levels in seawater samples is undertaken regularly by research groups all over the world, leading to a growing demand for techniques involving fewer toxic reagents, less time-consuming protocols and lower limits of detection. This review focuses on providing a brief but concise description of the latest methodologies developed to this end, outlining the advantages and disadvantages of the various protocols, chelating and dispersive agents and instruments used. Conclusions are drawn on the basis of the articles reviewed, highlighting improvements introduced in order to enhance the performance of the protocols. Copyright © 2014 Elsevier Ltd. All rights reserved.

Trehalose Analogues: Latest Insights in Properties and Biocatalytic Production

PubMed Central

Walmagh, Maarten; Zhao, Renfei; Desmet, Tom

2015-01-01

Trehalose (α-d-glucopyranosyl α-d-glucopyranoside) is a non-reducing sugar with unique stabilizing properties due to its symmetrical, low energy structure consisting of two 1,1-anomerically bound glucose moieties. Many applications of this beneficial sugar have been reported in the novel food (nutricals), medical, pharmaceutical and cosmetic industries. Trehalose analogues, like lactotrehalose (α-d-glucopyranosyl α-d-galactopyranoside) or galactotrehalose (α-d-galactopyranosyl α-d-galactopyranoside), offer similar benefits as trehalose, but show additional features such as prebiotic or low-calorie sweetener due to their resistance against hydrolysis during digestion. Unfortunately, large-scale chemical production processes for trehalose analogues are not readily available at the moment due to the lack of efficient synthesis methods. Most of the procedures reported in literature suffer from low yields, elevated costs and are far from environmentally friendly. “Greener” alternatives found in the biocatalysis field, including galactosidases, trehalose phosphorylases and TreT-type trehalose synthases are suggested as primary candidates for trehalose analogue production instead. Significant progress has been made in the last decade to turn these into highly efficient biocatalysts and to broaden the variety of useful donor and acceptor sugars. In this review, we aim to provide an overview of the latest insights and future perspectives in trehalose analogue chemistry, applications and production pathways with emphasis on biocatalysis. PMID:26084050

Parabolic distribution of circumeastern Snake River Plain seismicity and latest Quaternary faulting: Migratory pattern and association with the Yellowstone hotspot

NASA Astrophysics Data System (ADS)

Anders, Mark H.; Geissman, John Wm.; Piety, Lucille A.; Sullivan, J. Timothy

1989-02-01

The Intermountain and Idaho seismic belts within Idaho, Wyoming, and Montana form an unusual parabolic pattern about the axis of the aseismic eastern Snake River Plain (SRP). This pattern is also reflected in the distribution of latest Quaternary normal faults. Several late Cenozoic normal faults that trend perpendicular to the axis of the eastern SRP extend from the aseismic region to the region of latest Quaternary faulting and seismicity. A study of the late Miocene to Holocene displacement history of one of these, the Grand Valley fault system in southeastern Idaho and western Wyoming, indicates that a locus of high displacement rates has migrated away from the eastern SRP to its present location in southern Star Valley in western Wyoming. In Swan Valley the studied area closest to the eastern SRP, isotopic ages, and paleomagnetic data for over 300 samples from 47 sites on well-exposed late Cenozoic volcanic rocks (the tuff of Spring Creek, the tuff of Heise, the Huckleberry Ridge tuff, the Pine Creek Basalt, and an older tuff thought to be the tuff of Cosgrove Road) are used to demonstrate differences in the displacement rate on the Grand Valley fault over the last ˜10 m.y. Tectonic tilts for these volcanic rocks are estimated by comparing the results of paleomagnetic analyses in Swan Valley to similar analyses of samples from undeformed volcanic rocks outside of Swan Valley. Basin geometry and tilt axes are established using seismic reflection profiles and field mapping. Combining these data with the tilt data makes it possible to calculate displacement rates during discrete temporal intervals. An average displacement rate of ˜1.8 mm/yr is calculated for the Grand Valley fault in Swan Valley between 4.4 and 2.0 Ma. In the subsequent 2.0-m.y. interval the rate dropped 2 orders of magnitude to ˜0.014 mm/yr; during the preceding 5.5-m.y. interval the displacement rate is ˜0.15 mm/yr, or about 1 order of magnitude less than the rate between 4.4 and 2.0 Ma

Laparoscopic colorectal surgery: Current status and implementation of the latest technological innovations.

PubMed

Pascual, Marta; Salvans, Silvia; Pera, Miguel

2016-01-14

The introduction of laparoscopy is an example of surgical innovation with a rapid implementation in many areas of surgery. A large number of controlled studies and meta-analyses have shown that laparoscopic colorectal surgery is associated with the same benefits than other minimally invasive procedures, including lesser pain, earlier recovery of bowel transit and shorter hospital stay. On the other hand, despite initial concerns about oncological safety, well-designed prospective randomized multicentre trials have demonstrated that oncological outcomes of laparoscopy and open surgery are similar. Although the use of laparoscopy in colorectal surgery has increased in recent years, the percentages of patients treated with surgery using minimally invasive techniques are still reduced and there are also substantial differences among centres. It has been argued that the limiting factor for the use of laparoscopic procedures is the number of surgeons with adequate skills to perform a laparoscopic colectomy rather than the tumour of patients' characteristics. In this regard, future efforts to increase the use of laparoscopic techniques in colorectal surgery will necessarily require more efforts in teaching surgeons. We here present a review of recent controversies of the use of laparoscopy in colorectal surgery, such as in rectal cancer operations, the possibility of reproducing complete mesocolon excision, and the benefits of intra-corporeal anastomosis after right hemicolectomy. We also describe the results of latest innovations such as single incision laparoscopic surgery, robotic surgery and natural orifice transluminal endoscopic surgery for colon and rectal diseases.

Laparoscopic colorectal surgery: Current status and implementation of the latest technological innovations

PubMed Central

Pascual, Marta; Salvans, Silvia; Pera, Miguel

2016-01-01

The introduction of laparoscopy is an example of surgical innovation with a rapid implementation in many areas of surgery. A large number of controlled studies and meta-analyses have shown that laparoscopic colorectal surgery is associated with the same benefits than other minimally invasive procedures, including lesser pain, earlier recovery of bowel transit and shorter hospital stay. On the other hand, despite initial concerns about oncological safety, well-designed prospective randomized multicentre trials have demonstrated that oncological outcomes of laparoscopy and open surgery are similar. Although the use of laparoscopy in colorectal surgery has increased in recent years, the percentages of patients treated with surgery using minimally invasive techniques are still reduced and there are also substantial differences among centres. It has been argued that the limiting factor for the use of laparoscopic procedures is the number of surgeons with adequate skills to perform a laparoscopic colectomy rather than the tumour of patients’ characteristics. In this regard, future efforts to increase the use of laparoscopic techniques in colorectal surgery will necessarily require more efforts in teaching surgeons. We here present a review of recent controversies of the use of laparoscopy in colorectal surgery, such as in rectal cancer operations, the possibility of reproducing complete mesocolon excision, and the benefits of intra-corporeal anastomosis after right hemicolectomy. We also describe the results of latest innovations such as single incision laparoscopic surgery, robotic surgery and natural orifice transluminal endoscopic surgery for colon and rectal diseases. PMID:26811618

Recent results from Daya Bay

NASA Astrophysics Data System (ADS)

Chua, Ming-chung

2016-11-01

Utilizing powerful nuclear reactors as antineutrino sources, high mountains to provide ample shielding from cosmic rays in the vicinity, and functionally identical detectors with large target volume for near-far relative measurement, the Daya Bay Reactor Neutrino Experiment has achieved unprecedented precision in measuring the neutrino mixing angle θ13 and the neutrino mass squared difference |Δm2ee|. I will report the latest Daya Bay results on neutrino oscillations and light sterile neutrino search.

Latest Development and Application of Nb-Bearing High Strength Pipeline Steels

NASA Astrophysics Data System (ADS)

Zhang, Yongqing; Shang, Chengjia; Guo, Aimin; Zheng, Lei; Niu, Tao; Han, Xiulin

In order to solve the pollution problem emerging in China recently, China's central government is making great efforts to raise the percentage of natural gas consumption in the China's primary energy mix, which needs to construct big pipelines to transport natural gas from the nation's resource-rich western regions to the energy-starved east, as well as import from the Central Asia and Russia. With this mainstream trend, high strength, high toughness, heavy gauge, and large diameter pipeline steels are needed to improve the transportation efficiency. This paper describes the latest progresses in Nb-bearing high strength pipeline steels with regard to metallurgical design, development and application, including X80 coil with a thickness up to 22.0mm, X80 plate with a diameter as much as 1422mm, X80 plate with low-temperature requirements and low-Mn sour service X65 for harsh sour service environments. Moreover, based on widely accepted TMCP and HTP practices with low carbon and Nb micro-alloying design, this paper also investigated some new metallurgical phenomena based on powerful rolling mills and heavy ACC equipment.

Earth and Space Science Electronic Theater: State-of-the-Art Visualization from the Latest Remote Sensing Observations. High Definition Television on the SMM IMAX Screen with Ultra High Performance Projector

NASA Technical Reports Server (NTRS)

Hasler, A. F.; Starr, David (Technical Monitor)

2001-01-01

Fritz Hasler (NASA/Goddard) will demonstrate the latest Blue Marble Digital Earth technology. We will fly in from space through Terra, Landsat 7, to 1 m Ikonos "Spy Satellite" data to Washington, NYC, Chicago, and LA. You will see animations using the new 1 km global datasets from the EOS Terra satellite. Spectacular new animations from Terra, Landsat 7, and SeaWiFS will be presented. See the latest animations of the super hurricanes like, Floyd, Luis, and Mitch, from GOES & TRMM. See movies assembled using new low cost HDTV nonlinear editing equipment that is revolutionizing the way we communicate scientific results. See climate change in action with Global Land & Ocean productivity changes over the last 20 years. Remote sensing observations of ocean SST, height, winds, color, and El Nino from GOES, AVHRR, SSMI & SeaWiFS are put in context with atmospheric and ocean simulations. Compare symmetrical equatorial eddies observed by GOES with the simulations.

Latest COBE results, large-scale data, and predictions of inflation

NASA Technical Reports Server (NTRS)

Kashlinsky, A.

1992-01-01

One of the predictions of the inflationary scenario of cosmology is that the initial spectrum of primordial density fluctuations (PDFs) must have the Harrison-Zeldovich (HZ) form. Here, in order to test the inflationary scenario, predictions of the microwave background radiation (MBR) anisotropies measured by COBE are computed based on large-scale data for the universe and assuming Omega-1 and the HZ spectrum on large scales. It is found that the minimal scale where the spectrum can first enter the HZ regime is found, constraining the power spectrum of the mass distribution to within the bias factor b. This factor is determined and used to predict parameters of the MBR anisotropy field. For the spectrum of PDFs that reaches the HZ regime immediately after the scale accessible to the APM catalog, the numbers on MBR anisotropies are consistent with the COBE detections and thus the standard inflation can indeed be considered a viable theory for the origin of the large-scale structure in the universe.

Perennial stream discharge in the hyperarid Atacama Desert of northern Chile during the latest Pleistocene

PubMed Central

Nester, Peter L.; Gayó, Eugenia; Latorre, Claudio; Jordan, Teresa E.; Blanco, Nicolás

2007-01-01

A large fraction of the vital groundwater in the Atacama Desert of northern Chile is likely composed of “fossil” or “ancient” reserves that receive little or no recharge in today's hyperarid climate. Here, we present evidence for latest Pleistocene perennial streamflow in canyons from the hyperarid core of the Atacama Desert in northern Chile. Fluvial terraces in the Pampa del Tamarugal (PdT) basin (21°S) contain widespread fossil wood, in situ roots, and well preserved leaf litter deposits indicative of perennial surface flow currently absent in these channels. Nineteen radiocarbon dates on these deposits from four separate drainages within this endorheic basin indicate ages from 16,380 to 13,740 cal yr BP, synchronous with paleolake Tauca on the Bolivian Altiplano and other regional evidence for wetter conditions during the latest Pleistocene. Groundwater-fed riparian ecosystems and associated fluvial deposits abound today in the absence of direct rainfall in northern Atacama canyons with perennial discharge. Our relict riparian ecosystems from the PdT basin are indicative of conditions similar to these northern canyons. Given that discharge was higher than present during this time, we propose that these deposits represent the most important groundwater recharge events of the last 18,000 years. A lesser recharge event occurred during the Holocene, when phreatophytic trees also grew in these drainages between 1,070 and 700 cal yr BP, during the Medieval Climatic Anomaly. Taken together, our evidence lends further support for gradient changes in the equatorial Pacific as a major driver of hydrologic change in the Atacama on both centennial and millennial time scales. PMID:18056645

Radiocarbon studies of latest Pleistocene and Holocene lava flows of the Snake River Plain, Idaho: Data, lessons, interpretations

USGS Publications Warehouse

Kuntz, M.A.; Spiker, E. C.; Rubin, M.; Champion, D.E.; Lefebvre, R.H.

1986-01-01

Latest Pleistocene-Holocene basaltic lava fields of the Snake River Plain, Idaho, have been dated by the radiocarbon method. Backhoe excavations beneath lava flows typically yielded carbon-bearing, charred eolian sediment. This material provided most of the samples for this study; the sediment typically contains less than 0.2% carbon. Charcoal fragments were obtained from tree molds but only from a few backhoe excavations. Contamination of the charred sediments and charcoal by younger carbon components is extensive; the effects of contamination were mitigated but appropriate pretreatment of samples using acid and alkali leaches. Twenty of the more than 60 lava flows of the Craters of the Moon lava field have been dated; their ages range from about 15,000 to about 2000 yr B.P. The ages permit assignment of the flows to eight distinct eruptive periods with an average recurrence interval of about 2000 yr. The seven other latest Pleistocene-Holocene lava fields were all emplaced in short eruptive bursts. Their 14C ages (yr B.P.) are: Kings Bowl (2222?? 100), Wapi (2270 ?? 50), Hells Half Acre (5200 ?? 150), Shoshone (10,130 ?? 350), North Robbers and South Robbers (11.980 ?? 300), and Cerro Grande (13,380 ?? 350). ?? 1986.

Radiocarbon studies of latest Pleistocene and Holocene lava flows of the Snake River Plain, Idaho: Data, lessons, interpretations

NASA Astrophysics Data System (ADS)

Kuntz, Mel A.; Spiker, Elliott C.; Rubin, Meyer; Champion, Duane E.; Lefebvre, Richard H.

1986-03-01

Latest Pleistocene-Holocene basaltic lava fields of the Snake River Plain, Idaho, have been dated by the radiocarbon method. Backhoe excavations beneath lava flows typically yielded carbon-bearing, charred eolian sediment. This material provided most of the samples for this study; the sediment typically contains less than 0.2% carbon. Charcoal fragments were obtained from tree molds but only from a few backhoe excavations. Contamination of the charred sediments and charcoal by younger carbon components is extensive; the effects of contamination were mitigated but appropriate pretreatment of samples using acid and alkali leaches. Twenty of the more than 60 lava flows of the Craters of the Moon lava field have been dated; their ages range from about 15,000 to about 2000 yr B.P. The ages permit assignment of the flows to eight distinct eruptive periods with an average recurrence interval of about 2000 yr. The seven other latest Pleistocene-Holocene lava fields were all emplaced in short eruptive bursts. Their 14C ages (yr B.P.) are: Kings Bowl (2222± 100), Wapi (2270 ± 50), Hells Half Acre (5200 ± 150), Shoshone (10,130 ± 350), North Robbers and South Robbers (11.980 ± 300), and Cerro Grande (13,380 ± 350).

Seismic stratigraphy and depositional history of the Büyükçekmece Bay since Latest Pleistocene, Marmara Sea, Turkey

NASA Astrophysics Data System (ADS)

Vardar, Denizhan; Alp, Hakan; Alpar, Bedri

2018-02-01

High-resolution seismic data shed light on latest Pleistocene and Holocene sedimentation beneath the Büyükçekmece Bay, northern shelf area of the Marmara Sea, Turkey. Discontinuous fluvio-marine and marine deposits overlying the erosional truncation surface of Oligocene-Lower Miocene deposits are as thick as 30 m and preserved preferentially within the incised valleys that were controlled by some old faults. A series of prograding shoreline, laterally passing to the latest Pleistocene-Holocene valley-fill deposits, are thought to have accumulated mainly during times of shoreline transgression and sea-level rise. The overall morphology and stratigraphic setting observed in the Büyükçekmece Bay and at the southern outlet of the Bosphorus Strait have nearly same characteristics, implying that similar hydrodynamic conditions, erosional and depositional processes were mainly under the control of strong northerly flows during the Late Quaternary. These flows were less powerful in the Büyükçekmece region with decreased sediment input and smaller accommodation space.

Responses of East Asian Summer Monsoon to Natural and Anthropogenic Forcings in the 17 Latest CMIP5 Models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Song, Fengfei; Zhou, Tianjun; Qian, Yun

2014-01-31

In this study, we examined the responses of East Asian Summer Monsoon (EASM) to natural (solar variability and volcanic aerosols) and anthropogenic (greenhouse gasses and aerosols) forcings simulated in the 17 latest Coupled Model Intercomparison Program phase 5 (CMIP5) models with 105 realizations. The observed weakening trend of low-level EASM circulation during 1958-2001 is partly reproduced under all-forcing runs. A comparison of separate forcing experiments reveals that the aerosol-forcing plays a primary role in driving the weakened low-level monsoon circulation. The preferential cooling over continental East Asia caused by aerosol affects the monsoon circulation through reducing the land-sea thermal contrastmore » and results in higher sea level pressure over northern China. In the upper-level, both natural-forcing and aerosol-forcing contribute to the observed southward shift of East Asian subtropical jet through changing the meridional temperature gradient.« less

Juno’s Latest Close Flyby of Jupiter on This Week @NASA – February 3, 2017

NASA Image and Video Library

2017-02-03

NASA’s Juno spacecraft made its latest close flyby of Jupiter Feb. 2 -- passing about 2,700 miles above the planet’s clouds. This was the fourth close flyby since Juno began orbiting Jupiter last year on July 4. During these close passes instruments on the spacecraft probe beneath the cloud cover to collect scientific data about the planet's structure, atmosphere and magnetosphere. This information could help us better understand the planetary systems being discovered around other stars. Also, Cassini Sees Saturn’s Rings in Greater Detail, The Most Extreme Blazars, NASA at Super Bowl Event, NASA at NBA Black Heritage Celebration, and Day of Remembrance!

Simulating the Solar Wind Interaction with Comet 67P/Churyumov-Gerasimenko: Latest Results

NASA Astrophysics Data System (ADS)

Deca, J.; Divin, A. V.; Henri, P.; Eriksson, A. I.; Markidis, S.; Olshevsky, V.; Goldstein, R.; Myllys, M. E.; Horanyi, M.

2017-12-01

First observed in 1969, comet 67P/Churyumov-Gerasimenko was escorted for almost two years along its 6.45-yr elliptical orbit by ESA's Rosetta orbiter spacecraft. When a comet is sufficiently close to the Sun, the sublimation of ice leads to an outgassing atmosphere and the formation of a coma, and a dust and plasma tail. Comets are critical to decipher the physics of gas release processes in space. The latter result in mass-loaded plasmas, which more than three decades after the Active Magnetospheric Particle Tracer Explorers (AMPTE) space release experiments are still not fully understood. Using a 3D fully kinetic approach, we study the solar wind interaction with comet 67P/Churyumov-Gerasimenko, focusing in particular on the ion-electron dynamics for various outgassing rates. A detailed kinetic treatment of the electron dynamics is critical to fully capture the complex physics of mass-loading plasmas and to describe the strongly inhomogeneous plasma dynamics observed by Rosetta, down to electron kinetic scales.

Recent Observations of AG Pegasi's Latest Outburst Phase by Harvard Observing Project

NASA Astrophysics Data System (ADS)

Espinel, Jose Luis; Lewis, John; Budreviciute, Rimute; Bieryla, Allyson; Denham Alexander, Kate; Blanchard, Peter; Carmichael, Theron; Garrison, Lehman H.; Huang, Jane; Mayo, Andrew; McIntosh, Missy; Vanderburg, Andrew; Alam, Munazza; Cordova, Rodrigo; Gomez, Sebastian; Weaver, Ian; Yuan, Sihan; Price, Evander

2017-01-01

AG Pegasi (AG Peg) is a symbiotic binary star composed of a red supergiant and a white dwarf. Between 1860 and 1870, AG Peg brightened from magnitude 9 to 6, before gradually dimming. In 2015, the star began another brightening phase. The outbursts are thought to be caused by accretion of material onto the white dwarf. Once there is enough hydrogen accreted, hydrogen shell-burning starts leading to the the star’s evolution into a A-supergiant with a high mass-loss rate (Kenyon et al. 1993). The Harvard Observing Project (HOP) collected photometric data in BVRI filters using Harvard’s 16-inch Clay Telescope in the Fall term of 2015 and again in the Fall term of 2016. HOP is designed to get undergraduate students interested in astronomy and observing, and to allow graduate students opportunities to interact with undergraduates and get more observing/teaching experience. This study monitors the luminosity of AG Peg to constrain the amplitude and duration of the latest outburst.

[Mechanical thrombectomy in acute ischemic stroke. What is the position after the latest study results?].

PubMed

Hacke, W; Diener, H-C

2015-06-01

Mechanical devices for the recanalization of vessel occlusions in severe acute ischemic stroke have been developed for more than a decade. Several devices have been approved for clinical use on the basis of uncontrolled case series. Many neurologists have asked for randomized clinical trials comparing the new devices with standard treatment, e.g. thrombolytic therapy within a 4.5 h time window. The first 3 investigator initiated randomized trials published in 2013 failed to show superiority of mechanical thrombectomy over standard treatment. In the aftermath of these negative results several new trials with changes in design (e.g. shorter time window and only proximal vessel occlusions) and the use of modern devices with proven higher recanalization rates, so called stent retrievers, have been launched. In October 2014 the first of these new trials was presented and showed a clear superiority of thrombectomy. Based on this result interim analyses of five other studies were performed and most were prematurely terminated because of overwhelming efficacy. Only one trial testing another type of recanalization device failed to reach a statistically significant result. Currently five studies have already been published and two more studies have been presented at scientific conferences. This article provides an overview of the study protocols and the results of the individual studies, their common features and the characteristics of patients who benefit from this treatment. Finally, the consequences that these results may have for the treatment of patients with severe stroke caused by proximal vessel occlusion are discussed.

Future Wave Height Situation estimated by the Latest Climate Scenario around Funafuti Atoll, Tuvalu

NASA Astrophysics Data System (ADS)

Sato, D.; Yokoki, H.; Kuwahara, Y.; Yamano, H.; Kayanne, H.; Okajima, H.; Kawamiya, M.

2012-12-01

Sea-level rise due to the global warming is significant phenomenon to coastal region in the world. Especially the atoll islands, which are low-lying and narrow, have high vulnerability against the sea-level rise. Recently the improved future climate projection (MIROC-ESM) was provided by JAMSTEC, which adopted the latest climate scenarios based on the RCP (Representative Concentration Pathway) of the green house gasses. Wave field simulation including the latest sea-level rise pathway by MIROC-ESM was conducted to understand the change of significant wave heights in Funafuti Atoll, Tuvalu, which was an important factor to manage the coast protection. MIROC-ESM provides monthly sea surface height in the fine gridded world (1.5 degree near the equator). Wave field simulation was conducted using the climate scenario of RCP45 in which the radioactive forcing of the end of 21st century was stabilized to 4.5 W/m2. Sea-level rise ratio of every 10 years was calculated based on the historical data set from 1850 to 2005 and the estimated data set from 2006 to 2100. In that case, the sea-level increases by 10cm after 100 years. In this study, the numerical simulation of wave field at the rate of sea-level rise was carried out using the SWAN model. The wave and wind conditions around Funafuti atoll is characterized by two seasons that are the trade (Apr. - Nov.) and non-trade (Jan. - Mar., Dec.) wind season. Then, we set up the two seasonal boundary conditions for one year's simulation, which were calculated from ECMWF reanalysis data. Simulated results of significant wave heights are analyzed by the increase rate (%) calculated from the base results (Average for 2000 - 2005) and the results of 2100. Calculated increase rate of the significant wave height for both seasons was extremely high on the reef-flat. Maximum increase rates of the trade and non-trade wind season were 1817% and 686%, respectively. The southern part of the atoll has high increasing rate through the two

C4 expansion in the central Inner Mongolia during the latest Miocene and early Pliocene

NASA Astrophysics Data System (ADS)

Zhang, Chunfu; Wang, Yang; Deng, Tao; Wang, Xiaoming; Biasatti, Dana; Xu, Yingfeng; Li, Qiang

2009-10-01

The emergence of C4 photosynthesis in plants as a significant component of terrestrial ecosystems is thought to be an adaptive response to changes in atmospheric CO 2 concentration and/or climate during Neogene times and has had a profound effect on the global terrestrial biosphere. Although expansion of C4 grasses in the latest Miocene and Pliocene has been widely documented around the world, the spatial and temporal variations in the C4 expansion are still not well understood and its driving mechanisms remain a contentious issue. Here we present the results of carbon and oxygen isotope analyses of fossil and modern mammalian tooth enamel samples from the central Inner Mongolia. Our samples represent a diverse group of herbivorous mammals including deer, elephants, rhinos, horses and giraffes, ranging in age from the late Oligocene to modern. The δ13C values of 91 tooth enamel samples of early late-Miocene age or older, with the exception of two 13 Ma rhino samples (- 7.8 and - 7.6‰) and one 8.5 Ma suspected rhino sample (- 7.6‰), were all less than - 8.0‰ (VPDB), indicating that there were no C4 grasses present in their diets and thus probably few or no C4 grasses in the ecosystems of the central Inner Mongolia prior to ~ 8 Ma. However, 12 out of 26 tooth enamel samples of younger ages (~ 7.5 Ma to ~ 3.9 Ma) have δ13C values higher than - 8.0‰ (up to - 2.4‰), indicating that herbivores in the area had variable diets ranging from pure C3 to mixed C3-C4 vegetation during that time interval. The presence of C4 grasses in herbivores' diets (up to ~ 76% C4) suggests that C4 grasses were a significant component of the local ecosystems in the latest Miocene and early Pliocene, consistent with the hypothesis of a global factor as the driving mechanism of the late Miocene C4 expansion. Today, C3 grasses dominate grasslands in the central Inner Mongolia area. The retreat of C4 grasses from this area after the early Pliocene may have been driven by regional

Latest developments in on- and off-line inspection of bank notes during production

NASA Astrophysics Data System (ADS)

Brown, Stephen C.

2004-06-01

The inspection of bank notes is a highly labour intensive process where traditionally every note on every sheet is inspected manually. However with the advent of more and more sophisticated security features, both visible and invisible, and the requirement of cost reduction in the printing process, it is clear that automation is required. Machines for the automatic inspection of bank notes have been on the market for the past 10 to 12 years, but recent developments in technology have enabled a new generation of detectors and machines to be developed. This paper focuses on the latest developments in both the off-line and on-line inspection of bank notes covering not only the visible spectrum but also a new range of detectors for inspection some of the more common invisible features used as covert features in today's bank notes.

The Latest Mars Climate Database (MCD v5.1)

NASA Astrophysics Data System (ADS)

Millour, Ehouarn; Forget, Francois; Spiga, Aymeric; Navarro, Thomas; Madeleine, Jean-Baptiste; Pottier, Alizée; Montabone, Luca; Kerber, Laura; Lefèvre, Franck; Montmessin, Franck; Chaufray, Jean-Yves; López-Valverde, Miguel; González-Galindo, Francisco; Lewis, Stephen; Read, Peter; Huot, Jean-Paul; Desjean, Marie-Christine; the MCD/GCM development Team

2014-05-01

For many years, several teams around the world have developed GCMs (General Circulation Model or Global Climate Model) to simulate the environment on Mars. The GCM developed at the Laboratoire de Météorologie Dynamique in collaboration with several teams in Europe (LATMOS, France, University of Oxford, The Open University, the Instituto de Astrofisica de Andalucia), and with the support of ESA and CNES is currently used for many applications. Its outputs have also regularly been compiled to build a Mars Climate Database, a freely available tool useful for the scientific and engineering communities. The Mars Climate Database (MCD) has over the years been distributed to more than 150 teams around the world. Following the recent improvements inthe GCM, a new series of reference simulations have been run and compiled into a new version (version5.1) of the Mars Climate Database, released in the first half of 2014. To summarize, MCD v5.1 provides: - Climatologies over a series of dust scenarios: standard year, cold (ie: low dust), warm (ie: dusty atmosphere) and dust storm, all topped by various cases of Extreme UV solar inputs (low, mean or maximum). These scenarios differ from those of previous versions of the MCD (version 4.x) as they have been derived from home-made, instrument-derived (TES, THEMIS, MCS, MERs), dust climatology of the last 8 Martian years. - Mean values and statistics of main meteorological variables (atmospheric temperature, density, pressure and winds), as well as surface pressure and temperature, CO2 ice cover, thermal and solar radiative fluxes, dust column opacity and mixing ratio, [H20] vapor and ice columns, concentrations of many species: [CO], [O2], [O], [N2], [H2], [O3], ... - A high resolution mode which combines high resolution (32 pixel/degree) MOLA topography records and Viking Lander 1 pressure records with raw lower resolution GCM results to yield, within the restriction of the procedure, high resolution values of atmospheric

How gamma radiation processing systems are benefiting from the latest advances in information technology

NASA Astrophysics Data System (ADS)

Gibson, Wayne H.; Levesque, Daniel

2000-03-01

This paper discusses how gamma irradiation plants are putting the latest advances in computer and information technology to use for better process control, cost savings, and strategic advantages. Some irradiator operations are gaining significant benefits by integrating computer technology and robotics with real-time information processing, multi-user databases, and communication networks. The paper reports on several irradiation facilities that are making good use of client/server LANs, user-friendly graphics interfaces, supervisory control and data acquisition (SCADA) systems, distributed I/O with real-time sensor devices, trending analysis, real-time product tracking, dynamic product scheduling, and automated dosimetry reading. These plants are lowering costs by fast and reliable reconciliation of dosimetry data, easier validation to GMP requirements, optimizing production flow, and faster release of sterilized products to market. There is a trend in the manufacturing sector towards total automation using "predictive process control". Real-time verification of process parameters "on-the-run" allows control parameters to be adjusted appropriately, before the process strays out of limits. Applying this technology to the gamma radiation process, control will be based on monitoring the key parameters such as time, and making adjustments during the process to optimize quality and throughput. Dosimetry results will be used as a quality control measurement rather than as a final monitor for the release of the product. Results are correlated with the irradiation process data to quickly and confidently reconcile variations. Ultimately, a parametric process control system utilizing responsive control, feedback and verification will not only increase productivity and process efficiency, but can also result in operating within tighter dose control set points.

Continental crust melting induced by subduction initiation of the South Tianshan Ocean: Insight from the Latest Devonian granitic magmatism in the southern Yili Block, NW China

NASA Astrophysics Data System (ADS)

Bao, Zihe; Cai, Keda; Sun, Min; Xiao, Wenjiao; Wan, Bo; Wang, Yannan; Wang, Xiangsong; Xia, Xiaoping

2018-03-01

The Tianshan belt of the southwestern Central Asian Orogenic Belt was generated by Paleozoic multi-stage subduction and final closure of several extinct oceans, including the South Tianshan Ocean between the Kazakhstan-Yili and Tarim blocks. However, the subduction initiation and polarity of the South Tianshan Ocean remain issues of highly debated. This study presents new zircon U-Pb ages, geochemical compositions and Sr-Nd isotopes, as well as zircon Hf isotopic data of the Latest Devonian to Early Carboniferous granitic rocks in the Wusun Mountain of the Yili Paleozoic convergent margin, which, together with the spatial-temporal distributions of regional magmatic rocks, are applied to elucidate their petrogenesis and tectonic linkage to the northward subduction initiation of the South Tianshan Ocean. Our zircon U-Pb dating results reveal that these granites were emplaced at the time interval of 362.0 ± 1.2-360.3 ± 1.9 Ma, suggesting a marked partial melting event of the continental crust in the Latest Devonian to Early Carboniferous. These granites, based on their mineral compositions and textures, can be categorized as monzogranites and K-feldspar granites. Geochemically, both monzogranites and K-feldspar granites have characters of I-type granites with high K2O contents (4.64-4.83 wt.%), and the K-feldspar granites are highly fractionated I-type granites, while the monzogranites have features of unfractionated I-type granites. Whole-rock Sr-Nd isotopic modeling results suggest that ca. 20-40% mantle-derived magmas may be involved in magma mixing with continental crust partial melts to generate the parental magmas of the granites. The mantle-derived basaltic magmas was inferred not only to be a major component of magma mixture but also as an important heat source to fuse the continental crust in an extensional setting, which is evidenced by the high zircon saturation temperatures (713-727 °C and 760-782 °C) of the studied granites. The Latest Devonian to

Latest results and developments from the Hybrid Illinois Device for Research and Applications

NASA Astrophysics Data System (ADS)

Rizkallah, Rabel; Andruczyk, Daniel; Jeckell, Zachary Jon; Shone, Andrew John; Johnson, Daniel Scott; Allain, Jean Paul; Curreli, Davide; Ruzic, David N.; The Hidra Team

2017-10-01

The Hybrid Illinois Device for Research and Applications (HIDRA) is a five-period, l = 2, m = 5, toroidal fusion device operated at the University of Illinois at Urbana-Champaign (UIUC). It has a major radius R0 = 0.72 m and minor radius a = 0.19 m. Initial heating is achieved with 2.45 GHz electron cyclotron resonance heating (ECRH) at an on-axis magnetic field of B0 = 0.087 T which can go as high as B0 = 0.5 T. HIDRA will mainly be used as a classical stellarator, but can also run as a tokamak. This allows for both steady-state and transient regime operations. Experiments on HIDRA will primarily tackle the issue of plasma-material interactions (PMI) in fusion, and focus on developing innovative plasma facing component (PFC) technologies. Currently, research on flowing liquid lithium PFCs meant to be tested inside the machine in real-time operation, is being carried on. The first experiments run on HIDRA started in early 2016 in the low field region. Now, HIDRA is also capable of running in the high field zone, allowing for more interesting experiments and meaningful outcomes. Here, we present some of the initial results coming from the machine.

Recent Results from the Daya Bay Reactor Neutrino Experiment

NASA Astrophysics Data System (ADS)

Huang, En-Chuan

2016-11-01

The Daya Bay Reactor Neutrino Experiment is designed to precisely measure the mixing parameter sin2 2θ13 via relative measurements with eight functionally identical antineutrino detectors (ADs). In 2012, Daya Bay has first measured a non-zero sin2 2θ13 value with a significance larger than 5σ with the first six ADs. With the installation of two new ADs to complete the full configuration, Daya Bay has continued to increase statistics and lower systematic uncertainties for better precision of sin2 2θ13 and for the exploration of other physics topics. In this proceeding, the latest analysis results of sin2 2θ13 and |Δm 2 ee|, including a measurement made with neutron capture on Gadolinium and an independent measurement made with neutron capture on hydrogen are presented. The latest results of the search for sterile neutrino in the mass splitting range of 10-3 eV2 < |Δm 2 41| < 0.3 eV2 and the absolute measurement of the rate and energy spectrum of reactor antineutrinos will also be presented.

Overview of ECRH experimental results

NASA Astrophysics Data System (ADS)

Lloyd, Brian

1998-08-01

A review of the present status of electron cyclotron heating and current drive experiments in toroidal fusion devices is presented. In addition to basic heating and current drive studies the review also addresses advances in wave physics and the application of electron cyclotron waves for instability control, transport studies, pre-ionization/start-up assist, etc. A comprehensive overview is given with particular emphasis on recent advances since the major review of Erckmann and Gasparino (1994) ( 36 1869), including results from the latest generation of high-power, high-frequency experiments.

Latest Results of ILC High-Gradient R&D 9-cell Cavities at JLAB

DOE Office of Scientific and Technical Information (OSTI.GOV)

Geng, Rongli

2008-02-11

It has been over a year since JLAB started processing and testing ILC 9-cell cavities in the frame work of ILC high-gradient cavity R&D, aiming at the goal of a 35 MV/m gradient at a Q of 1E10 with a yield of 90%. The necessary cavity processing steps include field flatness tuning, electropolishing (EP), hydrogen out-gassing under vacuum, high-pressure water rinsing, clean room assembly, and low temperature bake. These are followed by RF test at 2 Kelvin. Ultrasonic cleaning with Micro-90, an effective post-EP rinsing recipe discovered at JLAB, is routinely used. Seven industry manufactured 9-cell TESLAshape cavities are processedmore » and tested repeatedly. So far, 33 EP cycles are accumulated, corresponding to more than 65 hours of active EP time. An emphasis put on RF testing is to discern cavity quench characteristics, including its nature and its location. Often times, the cavity performance is limited by thermal-magnetic quench instead of field emission. The quench field in some cavities is lower than 20 MV/m and remains unchanged despite repeated EP, implying material and/or fabrication defects. The quench field in some other cavities is high but changes unpredictably after repeated EP, suggesting processing induced defects. Based on our experience and results, several areas are identified where improvement is needed to improve cavity performance as well as yield.« less

The infrared imaging spectrograph (IRIS) for TMT: latest science cases and simulations

NASA Astrophysics Data System (ADS)

Wright, Shelley A.; Walth, Gregory; Do, Tuan; Marshall, Daniel; Larkin, James E.; Moore, Anna M.; Adamkovics, Mate; Andersen, David; Armus, Lee; Barth, Aaron; Cote, Patrick; Cooke, Jeff; Chisholm, Eric M.; Davidge, Timothy; Dunn, Jennifer S.; Dumas, Christophe; Ellerbroek, Brent L.; Ghez, Andrea M.; Hao, Lei; Hayano, Yutaka; Liu, Michael; Lopez-Rodriguez, Enrique; Lu, Jessica R.; Mao, Shude; Marois, Christian; Pandey, Shashi B.; Phillips, Andrew C.; Schoeck, Matthias; Subramaniam, Annapurni; Subramanian, Smitha; Suzuki, Ryuji; Tan, Jonathan C.; Terai, Tsuyoshi; Treu, Tommaso; Simard, Luc; Weiss, Jason L.; Wincentsen, James; Wong, Michael; Zhang, Kai

2016-07-01

The Thirty Meter Telescope (TMT) first light instrument IRIS (Infrared Imaging Spectrograph) will complete its preliminary design phase in 2016. The IRIS instrument design includes a near-infrared (0.85 - 2.4 micron) integral field spectrograph (IFS) and imager that are able to conduct simultaneous diffraction-limited observations behind the advanced adaptive optics system NFIRAOS. The IRIS science cases have continued to be developed and new science studies have been investigated to aid in technical performance and design requirements. In this development phase, the IRIS science team has paid particular attention to the selection of filters, gratings, sensitivities of the entire system, and science cases that will benefit from the parallel mode of the IFS and imaging camera. We present new science cases for IRIS using the latest end-to-end data simulator on the following topics: Solar System bodies, the Galactic center, active galactic nuclei (AGN), and distant gravitationally-lensed galaxies. We then briefly discuss the necessity of an advanced data management system and data reduction pipeline.

New primordial-magnetic-field limit from the latest LIGO S5 data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, S.

Since the energy momentum tensor of a magnetic field always contains a spin-2 component in its anisotropic stress, stochastic primordial magnetic field (PMF) in the early universe must generate stochastic gravitational-wave (GW) background. This process will greatly affect the relic gravitational wave (RGW), which is one of the major scientific goals of the laser interferometer GW detections. Recently, the fifth science (S5) run of laser interferometer gravitational-wave observatory (LIGO) gave a latest upper limit {Omega}{sub GW}<6.9x10{sup -6} on the RGW background. Utilizing this upper limit, we derive new PMF limits: for a scale of galactic cluster {lambda}=1 Mpc, the amplitudemore » of PMF, that produced by the electroweak phase transition, has to be weaker than B{sub {lambda}{<=}4}x10{sup -7} G; for a scale of supercluster {lambda}=100 Mpc, the amplitude of PMF has to be weaker than B{sub {lambda}{<=}9}x10{sup -11} G. In this manner, GW observation has potential to make interesting contributions to the study of primordial magnetic field.« less

Reconstruction of the Dark Energy Equation of State from the Latest Observations

NASA Astrophysics Data System (ADS)

Dai, Ji-Ping; Yang, Yang; Xia, Jun-Qing

2018-04-01

Since the discovery of the accelerating expansion of our universe in 1998, studying the features of dark energy has remained a hot topic in modern cosmology. In the literature, dark energy is usually described by w ≡ P/ρ, where P and ρ denote its pressure and energy density. Therefore, exploring the evolution of w is the key approach to understanding dark energy. In this work, we adopt three different methods, polynomial expansion, principal component analysis, and the correlated prior method, to reconstruct w with a collection of the latest observations, including the type-Ia supernova, cosmic microwave background, large-scale structure, Hubble measurements, and baryon acoustic oscillations (BAOs), and find that the concordance cosmological constant model (w = ‑1) is still safely consistent with these observational data at the 68% confidence level. However, when we add the high-redshift BAO measurement from the Lyα forest (Lyα FB) of BOSS DR11 quasars into the calculation, there is a significant impact on the reconstruction result. In the standard ΛCDM model, since the Lyα FB data slightly prefer a negative dark energy density, in order to avoid this problem, a dark energy model with a w significantly smaller than ‑1 is needed to explain this Lyα FB data. In this work, we find the consistent conclusion that there is a strong preference for the time-evolving behavior of dark energy w at high redshifts, when including the Lyα FB data. Therefore, we think that this Lyα FB data needs to be watched carefully attention when studying the evolution of the dark energy equation of state.

FY 2017 Oregon transportation needs and issues survey : summary of statewide results.

DOT National Transportation Integrated Search

2017-12-01

The Oregon Transportation Needs and Issues Survey was first conducted in 1993 and has been done roughly every two years. The latest survey was completed in Autumn 2016 (State fiscal year (FY) 2017). This report summarizes the results of the FY 2017 s...

An overview and the latest status of the Landsat Data Continuity Mission (LDCM)

NASA Astrophysics Data System (ADS)

Sabelhaus, Phil

2011-10-01

The Landsat Data Continuity Mission (LDCM) will provide continuity in the multi-decadal land use/land cover change measurements of the Landsat Program for scientific research. The project office at the National Aeronautics and Space Administration (NASA) Goddard Space Flight Center (GSFC) is responsible for the development, launch and post launch activation and check out for the Landsat Data Continuity Mission. The LDCM project is currently in its development phase with launch scheduled for December 2012 on an Atlas V launch vehicle provided by the Kennedy Space Center (KSC) from the Vandenberg Air Force Base (VAFB). The project is a partnership between NASA and the Department of the Interior (DOI)/United States Geological Survey (USGS). DOI/USGS is responsible for development of the ground system and will assume responsibility for satellite and ground system operations following the check-out period. This paper will provide an overview and the latest status of the LDCM mission.

New remains of the baluchithere Paraceratherium bugtiense(Pilgrim, 1910) from the Late/latest Oligocene of the Bugti hills, Balochistan, Pakistan

NASA Astrophysics Data System (ADS)

Antoine, Pierre-Olivier; Ibrahim Shah, S. M.; Cheema, Iqbal U.; Crochet, Jean-Yves; Franceschi, Dario de; Marivaux, Laurent; Métais, Grégoire; Welcomme, Jean-Loup

2004-10-01

New dental and postcranial remains referred to the giant rhinocerotoid Paraceratherium bugtiense are described, originating from its type locality (Lundo Chur), in eastern Balochistan (Pakistan). Probable sexual dimorphism is revealed on the lower incisors. The manus was tridactyl, with a reduced fifth metacarpal. The stratigraphic range of both P. bugtiense and the amynodontid Cadurcotherium indicum extends from the Early Early Oligocene to the Late/latest Oligocene in the Bugti Hills.

FY 2009 Oregon Transportation Needs and Issues Survey : Summary of Statewide Results

DOT National Transportation Integrated Search

2009-12-01

The Oregon Transportation Needs and Issues Survey was first conducted in 1993 and has been done roughly every two years. The latest survey was completed in the fall of 2008 (State fiscal year (FY) 2009). This report summarizes the results of the FY 2...

Latest Quaternary palaeoceanographic change in the eastern North Atlantic based upon a dinoflagellate cyst event ecostratigraphy.

PubMed

Harland, Rex; Polovodova Asteman, Irina; Morley, Audrey; Morris, Angela; Harris, Anthony; Howe, John A

2016-05-01

The analyses of dinoflagellate cyst records, from the latest Quaternary sediments recovered from DSDP Core 610A taken on the Feni Ridge in the southern Rockall Trough, and part of core MD01-2461 on the continental margin of the Porcupine Seabight in the eastern North Atlantic Ocean, has provided evidence for significant oceanographic change encompassing the Last Glacial Maximum (LGM) and part of the Holocene. This together with other published records has led to a regional evaluation of oceanographic change in the eastern North Atlantic over the past 68 ka, based upon a distinctive dinoflagellate event ecostratigraphy. These changes reflect changes in the surface waters of the North Atlantic Current (NAC), and perhaps the deeper thermohaline Atlantic Meridional Overturning Circulation (AMOC), driving fundamental regime changes within the phytoplanktonic communities. Three distinctive dinoflagellate cyst associations based upon both factor and cluster analyses have been recognised. Associations characterised by Bitectatodinium tepikiense (between 61.1 ± 6.2 to 13.4 ± 1.1 ka BP), Nematosphaeropsis labyrinthus (between 10.5 ± 0.3 and 11.45 ± 0.8 ka. BP), and the cyst of Protoceratium reticulatum (between 8.5 ± 0.9 and 5.2 ± 1.3 ka. BP) indicate major change within the eastern North Atlantic oceanography. The transitions between these changes occur over a relatively short time span (c.1.5 ka), given our sampling resolution, and have the potential to be incorporated into an event stratigraphy through the latest Quaternary as recommended by the INTIMATE (INTegrating Ice core, MArine and TErrestrial records) group. The inclusion of a dinoflagellate cyst event stratigraphy would highlight changes within the phytoplankton of the North Atlantic Ocean as a fully glacial world changed to our present interglacial.

Annual Research Review: Sleep problems in childhood psychiatric disorders--a review of the latest science.

PubMed

Gregory, Alice M; Sadeh, Avi

2016-03-01

Hippocrates flagged the value of sleep for good health. Nonetheless, historically, researchers with an interest in developmental psychopathology have largely ignored a possible role for atypical sleep. Recently, however, there has been a surge of interest in this area, perhaps reflecting increased evidence that disturbed or insufficient sleep can result in poor functioning in numerous domains. This review outlines what is known about sleep in the psychiatric diagnoses most relevant to children and for which associations with sleep are beginning to be understood. While based on a comprehensive survey of the literature, the focus of the current review is on the latest science (largely from 2010). There is a description of both concurrent and longitudinal links as well as possible mechanisms underlying associations. Preliminary treatment research is also considered which suggests that treating sleep difficulties may result in improvements in behavioural areas beyond sleep quality. To maximise progress in this field, there now needs to be: (a) greater attention to the assessment of sleep in children; (b) sleep research on a wider range of psychiatric disorders; (c) a greater focus on and examination of mechanisms underlying associations; (d) a clearer consideration of developmental questions and (e) large-scale well-designed treatment studies. While sleep problems may sometimes be missed by parents and healthcare providers; hence constituting a hidden risk for other psychopathologies - knowing about these difficulties creates unique opportunities. The current excitement in this field from experts in diverse areas including developmental psychology, clinical psychology, genetics and neuropsychology should make these opportunities a reality. © 2015 Association for Child and Adolescent Mental Health.

Neutrino Astronomy at the South Pole: latest Results from AMANDA-II

DOE Office of Scientific and Technical Information (OSTI.GOV)

Desiati, Paolo

2006-07-11

AMANDA-II is the largest neutrino telescope collecting data at the moment, and its main goal is to search for sources of high energy extra-terrestrial neutrinos. The detection of such sources could give non-controversial evidence for the acceleration of charged hadrons in cosmic objects like Supernova Remnants, Micro-quasars, Active Galactic Nuclei or Gamma Ray Bursts. No significant excess has been found in searching for neutrinos from both point-like and non-localized sources. However AMANDA-II has significantly improved analysis techniques for better signal-to-noise optimization. The km3-scale IceCube telescope will enlarge the observable energy range and improve the sensitivities of high energy neutrino searchesmore » due to its 30 times larger effective area.« less

Comparison of dark energy models: A perspective from the latest observational data

NASA Astrophysics Data System (ADS)

Li, Miao; Li, Xiaodong; Zhang, Xin

2010-09-01

We compare some popular dark energy models under the assumption of a flat universe by using the latest observational data including the type Ia supernovae Constitution compilation, the baryon acoustic oscillation measurement from the Sloan Digital Sky Survey, the cosmic microwave background measurement given by the seven-year Wilkinson Microwave Anisotropy Probe observations and the determination of H 0 from the Hubble Space Telescope. Model comparison statistics such as the Bayesian and Akaike information criteria are applied to assess the worth of the models. These statistics favor models that give a good fit with fewer parameters. Based on this analysis, we find that the simplest cosmological constant model that has only one free parameter is still preferred by the current data. For other dynamical dark energy models, we find that some of them, such as the α dark energy, constant w, generalized Chaplygin gas, Chevalliear-Polarski-Linder parametrization, and holographic dark energy models, can provide good fits to the current data, and three of them, namely, the Ricci dark energy, agegraphic dark energy, and Dvali-Gabadadze-Porrati models, are clearly disfavored by the data.

The Latest SORCE Solar Spectral Irradiance Data Release: Inter-Comparison and a First Look at TSIS SIM Measurement.

NASA Astrophysics Data System (ADS)

Beland, S.; Sandoval, L.; Vanier, B.; Elliott, J.; Harder, J. W.; Snow, M. A.; Woods, T. N.; Richard, E. C.; Pilewskie, P.

2017-12-01

The Spectral Irradiance Monitor (SIM), the SOLar STellar Irradiance Comparison Experiment (SOLSTICE), and the XUV Photometer System (XPS) instruments on board the Solar Radiation and Climate Experiment (SORCE) mission have been taking daily Solar spectral irradiance (SSI) measurements since April 2003. We present the latest data releases from these instruments, describing the improvements in the new datasets and the trends measured during Solar cycles 23 and 24. An inter-comparison of the SSI over the overlapping wavelengths for SIM and SOLSTICE is presented as well as, if the data is available, a comparison with the first light measurements from TSIS-SIM.

Climate change and carbon-cycling during the latest Cretaceous-Early Paleogene; a new 13.5 million year-long, orbital-resolution, stable isotope record from the South Atlantic

NASA Astrophysics Data System (ADS)

Barnet, J.; Littler, K.; Kroon, D.; Leng, M. J.; Westerhold, T.; Roehl, U.; Zachos, J. C.

2017-12-01

The "greenhouse" world of the latest Cretaceous-Early Paleogene ( 70-34 Ma) was characterised by multi-million year variability in climate and the carbon-cycle. Throughout this interval the pervasive imprint of orbital-cyclicity, particularly eccentricity and precession, is visible in elemental and stable isotope data obtained from multiple deep-sea sites. Periodic "hyperthermal" events, occurring largely in-step with these orbital cycles, have proved particularly enigmatic, and may be the closest, albeit imperfect, analogues for anthropogenic climate change. This project utilises CaCO3-rich marine sediments recovered from ODP Site 1262 at a paleo-depth of 3600 m on the Walvis Ridge, South Atlantic, of late Maastrichtian-mid Paleocene age ( 67-60 Ma). We have derived high-resolution (2.5-4 kyr) carbon and oxygen isotope data from the epifaunal benthic foraminifera species Nuttallides truempyi. Combining the new record with the existing Late Paleocene-Early Eocene record generated from the same site by Littler et al. (2014), yields a single-site reference curve detailing 13.5 million years of orbital cyclicity in paleoclimate and carbon cycle from the latest Cretaceous to near the peak warmth of the Early Paleogene greenhouse. Spectral analysis of this new combined dataset allows us to identify long (405-kyr) eccentricity, short (100-kyr) eccentricity, and precession (19-23-kyr) as the principle forcing mechanisms governing pacing of the background climate and carbon-cycle during this time period, with a comparatively weak obliquity (41-kyr) signal. Cross-spectral analysis suggests that changes in climate lead the carbon cycle throughout most of the record, emphasising the role of the release of temperature-sensitive carbon stores as a positive feedback to an initial warming induced by changes in orbital configuration. The expression of comparatively understudied Early Paleocene events, including the Dan-C2 Event, Latest Danian Event, and Danian/Selandian Transition

The latest generation in flexible bronchoscopes: a description and evaluation.

PubMed

Hsia, David W; Tanner, Nichole T; Shamblin, Clayton; Mehta, Hiren J; Silvestri, Gerard A; Musani, Ali I

2013-10-01

Since the introduction of the flexible bronchoscope over 50 years ago, bronchoscopists have seen vast improvement in the technology available for diagnostics and therapeutics in the bronchoscopy laboratory. We set forth to evaluate the latest evolution in flexible bronchoscopes with features designed to improve imaging and airway navigation. The BF-Q190, BF-H190, and/or BF-1TH190 bronchoscopes were evaluated prospectively in 105 patients undergoing bronchoscopy from November 2010 to August 2011 at 2 tertiary care centers in the United States. Data collected from each procedure included method of insertion, airway images, and therapeutic interventions. At the completion of the study, 10 bronchoscopists were surveyed using a 7-point Likert scale to identify the perceived benefits of the design. Insertion methods included nasal, oral, laryngeal mask airway or endotracheal tube, and tracheostomy. Procedures performed included bronchoalveolar lavage, endobronchial biopsy or brushing, transbronchial biopsy, transbronchial needle aspiration or injection, peripheral navigation, and large airway therapeutic interventions. Survey of bronchoscopists revealed that when compared with current bronchoscopes, the features rated as having the most significant impact on functionality are the 210-degree tip angulation (average 2.4/3) and rotational capability of the insertion tube (average 2.4/3). The new-generation flexible bronchoscope offers improvement in image quality, magnification options, unique insertion tube rotation, and an increased 210-degree distal tip angulation over currently available flexible bronchoscopes. The bronchoscopes are an overall improvement to the current generation of bronchoscopes. The increased tip angulation and novel rotating insertion tube add the most to improvement in functionality.

Latest Holocene evolution and human disturbance of a channel segment in the Hudson River Estuary

USGS Publications Warehouse

Klingbeil, A.D.; Sommerfield, C.K.

2005-01-01

The latest Holocene sedimentary record of a cohesive channel and subtidal shoal in the lower Hudson River Estuary was examined to elucidate natural (sea-level rise, sediment transport) and anthropogenic (bulkheading, dredging) influences on the recent morphodynamic evolution of the system. To characterize the seafloor and shallow subbottom, ??? 100 km of high-resolution seismic reflection profiles (chirp) were collected within a 20-km reach of the estuary and correlated with sediment lithologies provided by eight vibracores recovered along seismic lines. Sediment geochronology with 137Cs and 14C was used to estimate intermediate and long-term sedimentation rates, respectively, and historical bathymetric data were analyzed to identify regional patterns of accretion and erosion, and to quantify changes in channel geometry and sediment volume. The shoal lithosome originated around 4 ka presumably with decelerating eustatic sea level rise during the latest Holocene. Long-term sedimentation rates on the shoal (2.3-2.6 mm/yr) are higher than in the channel (2 mm/yr) owing to hydrodynamic conditions that preferentially sequester suspended sediment on the western side of the estuary. As a result, the shoal accretes oblique to the principal axis of tidal transport, and more rapidly than the channel to produce an asymmetric cross-section. Shoal deposits consist of tidally bedded muds and are stratified by minor erosion surfaces that seismic profiles reveal to extend for 10s of meters to kilometers. The frequency and continuity of these surfaces suggest that the surficial shoal is catastrophically stripped on decadal-centennial time scales by elevated tidal flows; tidal erosion maintains the shoal at a uniform depth below sea level and prevents it from transitioning to an intertidal environment. Consequently, the long-term sedimentation rate approximates the rate of sea-level rise in the lower estuary (1-3 mm/yr). After the mid 1800s, the natural geometry of the lower Hudson

Implications of latest Pennsylvanian to Middle Permian paleontological and U-Pb SHRIMP data from the Tecomate Formation to re-dating tectonothermal events in the Acatlán Complex, Southern Mexico

USGS Publications Warehouse

Keppie, J. Duncan; Sandberg, Charles A.; Miller, B.V.; Sanchez-Zavala, J. L.; Nance, R.D.; Poole, Forrest G.

2004-01-01

Limestones in the highly deformed Tecomate Formation, uppermost unit of the Acatla??n Complex, are latest Pennsylvanian-earliest Middle Permian in age rather than Devonian, the latter based on less diagnostic fossils. Conodont collections from two marble horizons now constrain its age to range from latest Pennsylvanian to latest Early Permian or early Middle Permian. The older collection contains Gondolella sp., Neostreptognathodus sp., and Streptognathodus sp., suggesting an oldest age limit close to the Pennsylvanian-Permian time boundary. The other collection contains Sweet-ognathus subsymmetricus, a short-lived species ranging only from Kungurian (latest Leonardian) to Wordian (earliest Guadelupian: 272 ?? 4 to 264 ?? 2 Ma). A fusilinid, Parafusulina c.f. P. antimonioensis Dunbar, in a third Tecomate marble horizon is probably Wordian (early Guadelupian, early Middle Permian). Furthermore, granite pebbles in a Tecomate conglomerate have yielded ???320-264 Ma U-Pb SHRIMP ages probably derived from the ???288 Ma, arc-related Totoltepec pluton. Collectively, these data suggest a correlation with two nearby units: (1) the Missourian-Leonardian carbonate horizons separated by a Wolfcampian(?) conglomerate in the upper part of the less deformed San Salvador Patlanoaya Formation; and (2) the clastic, Westphalian-Leonardian Matzitzi Formation. This requires that deformation in the Tecomate Formation be of Early-Middle Permian age rather than Devonian. These three formations are re-interpreted as periarc deposits with deformation related to oblique subduction. The revised dating of the Tecomate Formation is consistent with new data, which indicates that the unconformity between the Tecomate and the Piaxtla Group is mid-Carboniferous and corresponds to a tectonothermal event. ?? 2004 by V. H. Winston and Son, Inc. All rights reserved.

Condom use at first and latest sexual events among young people: evidence from a rural and peri-urban setting in Uganda.

PubMed

Tumwesigye, N M; Ingham, R; Holmes, D

2013-06-01

Condom use remains low among young people despite high prevalence of HIV, STIs, and unplanned pregnancy in Uganda. This paper presents patterns of condom use at first and latest sexual events and associated factors. The data were obtained from 445 sexually active unmarried people aged 15-24 from one peri-urban and another rural district. Stratified multi-stage cluster sampling technique was applied. Logistic regression was used to identify factors associated with condom use at each of the two sexual events, while multinomial logistic regression was used to establish factors correlated with condom use at both first and last sex. Factors associated with condom use at each event were residence in the peri-urban district and higher education attainment. Factors correlated with condom use at both first and last sex were residence in peri-urban district (p<0.001) and being in school (p<0.01). Alcohol consumption and age at first sex were only significant at one event. Some factors that influence condom use at first sex are different from those that affect condom use at latest sexual event. Prevention programmes against STIs, HIV and unplanned pregnancies among young people focus more on rural areas and those with minimal or no education.

Testing cosmic transparency with the latest baryon acoustic oscillations and type Ia supernovae data

NASA Astrophysics Data System (ADS)

Chen, Jun; Wu, Pu-Xun; Yu, Hong-Wei; Li, Zheng-Xiang

2013-06-01

Observations show that Type Ia supernovae (SNe Ia) are dimmer than expected from a matter dominated Universe. It has been suggested that this observed phenomenon can also be explained using light absorption instead of dark energy. However, there is a serious degeneracy between the cosmic absorption parameter and the present matter density parameter Ωm when one tries to place constraints on the cosmic opacity using SNe Ia data. We combine the latest baryon acoustic oscillation (BAO) and Union2 SNe Ia data in order to break this degeneracy. Assuming a flat ΛCDM model, we find that, although an opaque Universe is favored by SNe Ia+BAO since the best fit value of the cosmic absorption parameter is larger than zero, Ωm = 1 is ruled out at the 99.7% confidence level. Thus, cosmic opacity is not sufficient to account for the present observations and dark energy or modified gravity is still required.

PREFACE: 2nd International Workshop on Theoretical and Computational Physics (IWTCP-2): Modern Methods and Latest Results in Particle Physics, Nuclear Physics and Astrophysics and the 39th National Conference on Theoretical Physics (NCTP-39)

NASA Astrophysics Data System (ADS)

Hoang, Trinh Xuan; Ky, Nguyen Anh; Lan, Nguyen Tri; Viet, Nguyen Ai

2015-06-01

This volume contains selected papers presented at the 2nd International Workshop on Theoretical and Computational Physics (IWTCP-2): Modern Methods and Latest Results in Particle Physics, Nuclear Physics and Astrophysics and the 39th National Conference on Theoretical Physics (NCTP-39). Both the workshop and the conference were held from 28th - 31st July 2014 in Dakruco Hotel, Buon Ma Thuot, Dak Lak, Vietnam. The NCTP-39 and the IWTCP-2 were organized under the support of the Vietnamese Theoretical Physics Society, with a motivation to foster scientific exchanges between the theoretical and computational physicists in Vietnam and worldwide, as well as to promote high-standard level of research and education activities for young physicists in the country. The IWTCP-2 was also an External Activity of the Asia Pacific Center for Theoretical Physics (APCTP). About 100 participants coming from nine countries participated in the workshop and the conference. At the IWTCP-2 workshop, we had 16 invited talks presented by international experts, together with eight oral and ten poster contributions. At the NCTP-39, three invited talks, 15 oral contributions and 39 posters were presented. We would like to thank all invited speakers, participants and sponsors for making the workshop and the conference successful. Trinh Xuan Hoang, Nguyen Anh Ky, Nguyen Tri Lan and Nguyen Ai Viet

Holocene and latest Pleistocene oblique dextral faulting on the southern Inyo Mountains fault, Owens Lake basin, California

USGS Publications Warehouse

Bacon, S.N.; Jayko, A.S.; McGeehin, J.P.

2005-01-01

The Inyo Mountains fault (IMF) is a more or less continuous range-front fault system, with discontinuous late Quaternary activity, at the western base of the Inyo Mountains in Owens Valley, California. The southern section of the IMF trends ???N20??-40?? W for at least 12 km at the base of and within the range front near Keeler in Owens Lake basin. The southern IMF cuts across a relict early Pliocene alluvial fan complex, which has formed shutter ridges and northeast-facing scarps, and which has dextrally offset, well-developed drainages indicating long-term activity. Numerous fault scarps along the mapped trace are northeast-facing, mountain-side down, and developed in both bedrock and younger alluvium, indicating latest Quaternary activity. Latest Quaternary multiple- and single-event scarps that cut alluvium range in height from 0.5 to 3.0 m. The penultimate event on the southern IMF is bracketed between 13,310 and 10,590 cal years B.P., based on radiocarbon dates from faulted alluvium and fissure-fill stratigraphy exposed in a natural wash cut. Evidence of the most recent event is found at many sites along the mapped fault, and, in particular, is seen in an ???0.5-m northeast-facing scarp and several right-stepping en echelon ???0.5-m-deep depressions that pond fine sediment on a younger than 13,310 cal years B.P. alluvial fan. A channel that crosses transverse to this scarp is dextrally offset 2.3 ?? 0.8 m, providing a poorly constrained oblique slip rate of 0.1-0. 3 m/ k.y. The identified tectonic geomorphology and sense of displacement demonstrate that the southern IMF accommodates predominately dextral slip and should be integrated into kinematic fault models of strain distribution in Owens Valley.

Invited Parallel Talk: Lattice results on nucleon/roper properties

NASA Astrophysics Data System (ADS)

Lin, Huey-Wen

2009-12-01

In this proceeding, I review the attempts to calculate the Nucleon resonance (including Roper as first radially excited state of nucleon and other excited states) using lattice quantum chromodynamics (QCD). The latest preliminary results from Hadron Spectrum Collaboration (HSC) with mπ thickapprox 380 MeV are reported. The Sachs electric form factor of the proton and neutron and their transition with the Roper at large Q2 are also updated in this work.

Latest Community Coordinated Modeling Center (CCMC) services and innovative tools supporting the space weather research and operational communities.

NASA Astrophysics Data System (ADS)

Mendoza, A. M. M.; Rastaetter, L.; Kuznetsova, M. M.; Mays, M. L.; Chulaki, A.; Shim, J. S.; MacNeice, P. J.; Taktakishvili, A.; Collado-Vega, Y. M.; Weigand, C.; Zheng, Y.; Mullinix, R.; Patel, K.; Pembroke, A. D.; Pulkkinen, A. A.; Boblitt, J. M.; Bakshi, S. S.; Tsui, T.

2017-12-01

The Community Coordinated Modeling Center (CCMC), with the fundamental goal of aiding the transition of modern space science models into space weather forecasting while supporting space science research, has been serving as an integral hub for over 15 years, providing invaluable resources to both space weather scientific and operational communities. CCMC has developed and provided innovative web-based point of access tools varying from: Runs-On-Request System - providing unprecedented global access to the largest collection of state-of-the-art solar and space physics models, Integrated Space Weather Analysis (iSWA) - a powerful dissemination system for space weather information, Advanced Online Visualization and Analysis tools for more accurate interpretation of model results, Standard Data formats for Simulation Data downloads, and Mobile apps to view space weather data anywhere to the scientific community. In addition to supporting research and performing model evaluations, CCMC also supports space science education by hosting summer students through local universities. In this poster, we will showcase CCMC's latest innovative tools and services, and CCMC's tools that revolutionized the way we do research and improve our operational space weather capabilities. CCMC's free tools and resources are all publicly available online (http://ccmc.gsfc.nasa.gov).

An Ecological Tipping Point Defined by Shallow Marine Foraminifera in the latest Paleocene

NASA Astrophysics Data System (ADS)

Robinson, M. M.; Spivey, W.

2016-12-01

The Paleocene-Eocene Thermal Maximum (PETM) is recognized in marine sediments by a carbonate dissolution zone, the extinction or turnover of benthic taxa, and a radiation of planktic excursion taxa, all accompanied by a rapid-onset, negative carbon isotope excursion (CIE). We present foraminiferal evidence from shallow marine sediments in southeastern Maryland, USA, where accumulation rates are high, for a minor ocean acidification event in the latest Paleocene that coincides with a relatively small (-2‰) CIE. This pre-onset excursion (POE) precedes the larger (-4‰) PETM CIE onset and dissolution event. During the POE, the benthic assemblage is reconfigured toward agglutinated species in order to adapt to increased acidity, and the planktic assemblage begins to speciate due to perturbed mixed layer conditions. The benthic assemblage returns to normal, without interruption, as the POE recovers, but planktic excursion taxa continue to appear in very low numbers. This is contrasted to the major ocean acidification event associated with the PETM CIE onset that results in a zone of complete dissolution followed by distinctive benthic and planktic foraminiferal assemblages. Our microfossil evidence documents a biotic response to bottom water and mixed layer perturbations that illustrates how coastal ecosystems react to both moderate and severe ocean acidification events, bracketing the ecological tipping point of shallow marine ecosystems. The POE, roughly half the magnitude of the CIE onset, provides insight into the nature of the initial effects of climate perturbation as well as an example of one that is fully recoverable. It is here that research aimed to better understand the long-term effects and reversibility of modern deteriorating oceanic conditions should focus. This study provides an initial metric by which to measure modern ecosystem disturbances and will help to define the tipping point for the shallow marine environment.

Comparing Two Examination Results Using Means of Sample Means and Control Charts

ERIC Educational Resources Information Center

Alabi-Labaika, A. Bisi; Ahani, E.

2015-01-01

Some examination candidates submit their scripts first, sometimes, for recognition as being brilliant, and some do for not knowing what to write. However, some equally submit last because they want to dot i's and cross t's. The objective of this research is to compare the results of both the earliest and latest submissions with the aim of finding…

Latest Data on Thermohaline Structure and Circulation of the Dying Aral Sea

NASA Astrophysics Data System (ADS)

Izhitsky, Alexander; Zavialov, Peter

2010-05-01

The results of the latest expedition of the Shirshov Institute to the Aral Sea are reported. The survey encompassed 15 field days in August, 2009. An interdisciplinary oceanographic study in the western basin of the sea was conducted during the expedition. Vertical profiles of temperature, salinity and fluorescence were obtained using a CTD profiler at 8 stations across the western basin. Two mooring stations equipped with current meters, one at the surface and one in the bottom layer at each station, as well as pressure gauges at the bottom, were deployed for 5 days in the deepest portion of the western basin. One of the stations was installed at the western slope of the basin, while the other one was positioned at the eastern slope. A portable automatic meteorological station, continuously recording the variability of wind and principal meteorological parameters, was installed near the mooring sites. The vertical structure of the themohaline fields exhibited a 3-layered pattern, with local salinity maxima in the upper mixed layer and at the bottom. The intermediate layer was characterized by a core of minimum salinity and temperature, also accompanied by maximum fluorescence. Such a pattern indicates that the signature of the denser, saltier water originating from the eastern basin is still evident, even though the eastern basin itself dried up almost completely during the summer of 2009. The surface salinity was around 136 ppt, which constituted a notable increase for about 20 ppt since the summer of 2008. Over the same period, sea level decreased by 164 cm since the summer of 2008. Analysis of the current measurements data along with the meteorological data records demonstrated that the mean basin-scale surface circulation of the Large Aral Sea is likely to have remained anticyclonic, whilst the near-bottom circulation appears to be cyclonic. The current velocity and level anomalies responded energetically to winds. Correlation analysis of the velocity series

The Laminated Marca Shale: High-Frequency Climate Cycles From the Latest Cretaceous

NASA Astrophysics Data System (ADS)

Davies, A.; Kemp, A. E.; Weedon, G.; Barron, J. A.

2005-12-01

The Latest Cretaceous (Maastrichtian) Marca Shale Member, California, displays a well-preserved record of alternating terrigenous and diatomaceous laminae couplets, remarkably similar in lithology to recent laminated sediments from the Gulf of California and Santa Barbara Basin. This similarity, together with the recognition of intra- and inter-annual variability in the diatom flora, implies an annual origin for these couplets. High-resolution backscattered electron imagery has identified two sublaminae types within the varved succession; near monospecific lamina of Chaetoceros-type resting spore and of large Azpeitiopsis morenoensis. The composition and occurrence of these laminae is similar to ENSO forced intra-annual variability of diatom flora along the modern Californian margin. Relative thickness variations in terrigenous and biogenic laminae (proxies for precipitation and productivity respectively) also exhibit similar characteristics to variability in Quaternary varves from the Santa Barbara Basin, shown to be imparted by ENSO forcing. In order to track changes in the levels of bottom water oxygenation within the basin, a bioturbation index was established. Periods when bioturbation was minimal (enhanced benthic anoxia) coincide with times of greatest diatomaceous export flux and also lowest flux of detrital material. Conversely, periods of enhanced bioturbation correspond with reduced diatomaceous export flux and an increased flux of detrital material, comparable with ENSO forced variations in diatomaceous and terrigenous export flux and associated benthic oxygenation levels in Pleistocene varves off the Californian margin. Power spectra obtained from time-series analysis of the bioturbation index and laminae thickness variations exhibit strong signals within the ENSO band. This research implies that high-frequency climate perturbations are inherent components of the climate system and that ENSO-type variability was not confined to the dynamic climate

Stratigraphy and structural development of the southwest Isla Tiburón marine basin: Implications for latest Miocene tectonic opening and flooding of the northern Gulf of California

USGS Publications Warehouse

Bennett, Scott E. K.; Oskin, Michael; Dorsey, Rebecca; Iriondo, Alexander; Kunk, Michael J.

2015-01-01

Accurate information on the timing of earliest marine incursion into the Gulf of California (northwestern México) is critical for paleogeographic models and for understanding the spatial and temporal evolution of strain accommodation across the obliquely divergent Pacific-North America plate boundary. Marine strata exposed on southwest Isla Tiburón (SWIT) have been cited as evidence for a middle Miocene marine incursion into the Gulf of California at least 7 m.y. prior to plate boundary localization ca. 6 Ma. A middle Miocene interpretation for SWIT marine deposits has played a large role in subsequent interpretations of regional tectonics and rift evolution, the ages of marine basins containing similar fossil assemblages along ~1300 km of the plate boundary, and the timing of marine incursion into the Gulf of California. We report new detailed geologic mapping and geochronologic data from the SWIT basin, an elongate sedimentary basin associated with deformation along the dextral-oblique La Cruz fault. We integrate these results with previously published biostratigraphic and geochronologic data to bracket the age of marine deposits in the SWIT basin and show that they have a total maximum thickness of ~300 m. The 6.44 ± 0.05 Ma (Ar/Ar) tuff of Hast Pitzcal is an ash-flow tuff stratigraphically below the oldest marine strata, and the 6.01 ± 0.20 Ma (U/Pb) tuff of Oyster Amphitheater, also an ash-flow tuff, is interbedded with marine conglomerate near the base of the marine section. A dike-fed rhyodacite lava flow that caps all marine strata yields ages of 3.51 ± 0.05 Ma (Ar/Ar) and 4.13 ± 0.09 Ma (U/Pb) from the base of the flow, consistent with previously reported ages of 4.16 ± 1.81 Ma (K-Ar) from the flow top and (K-Ar) 3.7 ± 0.9 Ma from the feeder dike. Our new results confirm a latest Miocene to early Pliocene age for the SWIT marine basin, consistent with previously documented latest Miocene to early Pliocene (ca. 6.2-4.3 Ma) planktonic and benthic

The Latest Succession of Dinosaur Tracksites in Europe: Hadrosaur Ichnology, Track Production and Palaeoenvironments

PubMed Central

Vila, Bernat; Oms, Oriol; Fondevilla, Víctor; Gaete, Rodrigo; Galobart, Àngel; Riera, Violeta; Canudo, José Ignacio

2013-01-01

A comprehensive review and study of the rich dinosaur track record of the Tremp Formation in the southern Pyrenees of Spain (Southwestern Europe) shows a unique succession of footprint localities prior to the end-Cretaceous mass extinction event. A description of some 30 new tracksites and data on sedimentary environments, track occurrence and preservation, ichnology and chronostratigraphy are provided. These new track localities represent various facies types within a diverse set of fluvial environments. The footprint discoveries mostly represent hadrosaurian and, less abundantly, to sauropod dinosaurs. The hadrosaur tracks are significantly smaller in size than, but morphologically similar to, those of North America and Asia and are attributable to the ichnogenus Hadrosauropodus. The track succession, with more than 40 distinct track levels, indicates that hadrosaur footprints in the Ibero-Armorican region occur predominantly in the late Maaastrichtian (at least above the early Maastrichtian–late Maastrichtian boundary). The highest abundance is found noticeably found in the late Maastrichtian, with tracks occurring in the C29r magnetochron, within about the latest 300,000 years of the Cretaceous. PMID:24019873

Evaluation of MR issues for the latest standard brands of orthopedic metal implants: plates and screws.

PubMed

Zou, Yue-Fen; Chu, Bin; Wang, Chuan-Bing; Hu, Zhi-Yi

2015-03-01

The study was performed to evaluate magnetic resonance (MR) issues for the latest standard brands of plates and screws used in orthopedic surgery at a 1.5-T MR system, including the safety and metallic artifacts. The plates and screws (made of titanium alloy and stainless steel materials, according to the latest standard brands) were assessed for displacement in degrees, MRI-related heating and artifacts at a 1.5-T MR system. The displacement in degrees of the plates and screws was evaluated on an angel-measurement instrument at the entrance of the MR scanner. The MRI-related heating was assessed on a swine leg fixed with a plate by using a "worst-case" pulse sequence. A rectangular water phantom was designed to evaluate metallic artifacts of a screw on different sequences (T1/T2-weighted FSE, STIR, T2-FSE fat saturation, GRE, DWI) and then artifacts were evaluated on T2-weighted FSE sequence by modifying the scanning parameters including field of view (FOV), echo train length (ETL) and bandwidth to identify the influence of parameters on metallic artifacts. 15 volunteers with internal vertebral fixation (titanium alloy materials) were scanned with MR using axial and sagittal T2-FSE, sagittal T2-FSE fat suppression and STIR with conventional and optimized parameters, respectively. Then all images were graded by two experienced radiologists having the experience of more than 7 years under double-blind studies that is neither of them knew which was conventional parameter group and optimized parameter group. The average deflection angle of titanium alloy and stainless steel implants were 4.3° and 7.7°, respectively, (less than 45°) which indicated that the magnetically induced force was less than the weight of the object. The deflection angle of the titanium alloy implants was less than the stainless steel one (t=9.69, P<0.001). The average temperature changes of titanium alloy before and after the scan was 0.48°C and stainless steel implants was 0.74�

Results of the Trace Contaminant Control Needs Evaluation and Sizing Study for Space Suit Life Support Development

NASA Technical Reports Server (NTRS)

Paul, Heather L.; Jennings, Mallory A.

2009-01-01

The Trace Contaminant Control System (TCCS), located within the ventilation loop of the Portable Life Support System (PLSS) of the Constellation Space Suit Element (CSSE), is responsible for removing hazardous trace contaminants from the space suit ventilation flow. This paper summarizes the results of a trade study that evaluated if trace contaminant control could be accomplished without a TCCS, relying on suit leakage, ullage loss from the carbon dioxide and humidity control system, and other factors. Trace contaminant generation rates were revisited to verify that values reflect the latest designs for CSSE pressure garment materials and PLSS hardware. Additionally, TCCS sizing calculations were performed and a literature survey was conducted to review the latest developments in trace contaminant technologies.

From first to latest imaging technology: Revisiting the first mummy investigated with X-ray in 1896 by using dual-source computed tomography.

PubMed

Zesch, Stephanie; Panzer, Stephanie; Rosendahl, Wilfried; Nance, John W; Schönberg, Stefan O; Henzler, Thomas

2016-01-01

The aim of this study was to systematically reinvestigate the first human mummy that was ever analyzed with X-ray imaging in 1896, using dual-source computed tomography (DSCT) in order to compare the earliest and latest imaging technologies, to estimate preservation, age at death, sex, anatomical variants, paleopathological findings, mummification, embalming and wrapping of the child mummy from ancient Egypt. Radiocarbon dating was used to determine the mummy's age and to specify the child's living period in the Egyptian chronology. The ancient Egyptian child mummy is kept in the Senckenberg Museum of Natural History in Frankfurt am Main, Germany. An accelerator mass spectrometer (MICADAS) was used for radiocarbon dating. DSCT was performed using a 2 × 64 slice dual-source CT system (Siemens Healthineers, Forchheim, Germany). A thorough visual examination of the mummy, a systematic radiological evaluation of the DICOM datasets, and established methods in physical anthropology were applied to assess the bio-anthropological data and the post mortem treatment of the body. Radiocarbon dating yielded a calibrated age between 378 and 235 cal BC (95.4% confidence interval), corresponding with the beginning of the Ptolemaic period. The mummy was a male who was four to five years old at the time of death. Remnants of the brain and inner organs were preserved by the embalmers, which is regularly observed in ancient Egyptian child mummies. Skin tissue, inner organs, tendons and/or musculature, cartilage, nerves and vasculature could be identified on the DSCT dataset. The dental health of the child was excellent. Anatomical variants and pathological defects included a congenital Pectus excavatum deformity, hepatomegaly, Harris lines, and longitudinal clefts in the ventral cortices of both femora. Our results highlight the enormous progress achieved form earliest to latest imaging technology for advanced mummy research using the first human mummy investigated with X

Switching and augmentation strategies for antipsychotic medications in acute-phase schizophrenia: latest evidence and place in therapy

PubMed Central

Hatta, Kotaro; Sugiyama, Naoya; Ito, Hiroto

2018-01-01

In terms of effectiveness of antipsychotics in schizophrenia, discrepancy often exists between results from double-blind randomized controlled trials and observations in emergency or acute-phase clinical practice. For instance, the antipsychotic switching strategy is not always applicable in emergency or acute-phase situations, and augmentation of another antipsychotic is occasionally done instead. In this review, we discuss strategies for early nonresponse to an antipsychotic drug such as switching and augmentation from the perspective of emergency and acute-phase treatment. We searched PubMed for the latest evidence on switching and augmentation strategies of antipsychotics for an emergency or acute-phase period. For risperidone and olanzapine, there is some evidence on switching and augmentation strategies in the management of acute-phase schizophrenia. There may be responders to olanzapine alone among early nonresponders to risperidone, whereas there may be few responders to risperidone alone among early nonresponders to olanzapine. However, there is still insufficient evidence at this time for application of these findings to routine clinical practice. For other antipsychotics, there is little evidence for their augmentation in acute-phase practice. We should be wary of polypharmacy, as multiple agents are too often prescribed by clinicians when not warranted. Considering current evidence, we propose how to switch antipsychotics in the acute phase of schizophrenia in routine practice. PMID:29854396

Musett: A segmented Si array for Recoil-Decay-Tagging studies at VAMOS

NASA Astrophysics Data System (ADS)

Theisen, Ch.; Jeanneau, F.; Sulignano, B.; Druillole, F.; Ljungvall, J.; Paul, B.; Virique, E.; Baron, P.; Bervas, H.; Clément, E.; Delagnes, E.; Dijon, A.; Dossat, E.; Drouart, A.; Farget, F.; Flouzat, Ch.; De France, G.; Görgen, A.; Houarner, Ch.; Jacquot, B.; Korten, W.; Lebertre, G.; Lecornu, B.; Legeard, L.; Lermitage, A.; Lhenoret, S.; Marry, C.; Maugeais, C.; Menager, L.; Meunier, O.; Navin, A.; Nizery, F.; Obertelli, A.; Rauly, E.; Raine, B.; Rejmund, M.; Ropert, J.; Saillant, F.; Savajols, H.; Schmitt, Ch.; Tripon, M.; Wanlin, E.; Wittwer, G.

2014-05-01

A new segmented silicon-array called MUSETT has been built for the study of heavy elements using the Recoil-Decay-Tagging technique. MUSETT is located at the focal plane of the VAMOS spectrometer at GANIL and is used in conjunction with a γ-ray array at the target position. This paper describes the device, which consists of four 10×10 cm2 Si detectors and its associated front-end electronics based on highly integrated ASICs electronics. The triggerless readout electronics, the data acquisition and the analysis tools developed for its characterization are presented. This device was commissioned at GANIL with the EXOGAM γ-ray spectrometer using the fusion-evaporation reaction 197Au(22Ne,5n)214Ac. Additionally, the performance of the VAMOS Wien filter used during the in-beam commissioning is also reported.

TU-G-201-01: What Therapy Physicists Need to Know About CT and PET/CT: Terminology and Latest Developments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hua, C.

This session will update therapeutic physicists on technological advancements and radiation oncology features of commercial CT, MRI, and PET/CT imaging systems. Also described are physicists’ roles in every stage of equipment selection, purchasing, and operation, including defining specifications, evaluating vendors, making recommendations, and optimal and safe use of imaging equipment in radiation oncology environment. The first presentation defines important terminology of CT and PET/CT followed by a review of latest innovations, such as metal artifact reduction, statistical iterative reconstruction, radiation dose management, tissue classification by dual energy CT and spectral CT, improvement in spatial resolution and sensitivity in PET, andmore » potentials of PET/MR. We will also discuss important technical specifications and items in CT and PET/CT purchasing quotes and their impacts. The second presentation will focus on key components in the request for proposal for a MRI simulator and how to evaluate vendor proposals. MRI safety issues in radiation Oncology, including MRI scanner Zones (4-zone design), will be discussed. Basic MR terminologies, important functionalities, and advanced features, which are relevant to radiation therapy, will be discussed. In the third presentation, justification of imaging systems for radiation oncology, considerations in room design and construction in a RO department, shared use with diagnostic radiology, staffing needs and training, clinical/research use cases and implementation, will be discussed. The emphasis will be on understanding and bridging the differences between diagnostic and radiation oncology installations, building consensus amongst stakeholders for purchase and use, and integrating imaging technologies into the radiation oncology environment. Learning Objectives: Learn the latest innovations of major imaging systems relevant to radiation therapy Be able to describe important technical specifications of

Latest climate changes in Romania :tornadoes

NASA Astrophysics Data System (ADS)

Pop, Elena

2014-05-01

Latest climate changes in Romania :tornadoes As climate change has been considered a research priority in the European Strategy for enduring development , I have done a detailed research with my students of the new climate change that has been going on in Romania for the past decade. More precisely I have studied together with my students the phenomenon of tornadoes that have seriously affected on some occasions some our our country's locations, such as Facaeni, in the county of Ialomita, in August 2002. A quite unusual phenomenon occurred on that location situated at 44.56 degrees northern latitude and at 27.89 degrees eastern longitude, that caused severe damage to the local environment and three persons lost their lives in the process, as well as other thirty people suffering from bad injuries. The magnitude of that strong phenomenon rose on the Fujita scale at level F3 which implied wing gusts between 252-300 km/ hour . A main cause of occurrence of such a severe weather was the difference in temperature of two huge air masses, one of Polar origin, and other coming from tropical latitudes . Their crossroads was on that precise territory of Romania. The duration of the worst part of the tornado path lasted only for two minutes, but the consequences of its passage were colossal : total destruction of 33 households, and other 395 were partially damaged, 1,000 people afflicted by the devastation and 100 acres of acacia tree forest ripped off the ground. The first ever recorded tornado phenomenon in Romania was around 1894-1896, considered at that time " a freak of nature" was seen as a cloud formation abnormality , an uncontrolled force of nature that had a huge impact , and at the same time, it vanished into "thin air " fast. The most affected areas in Romania by tornadoes are the south-eastern planes where the cloud formations can create fast columns of air rotating up to 500 km/hour. The local people compared the cloud funnels created on the planes to "serpents

Latest advances in confocal microscopy of skin cancers toward guiding patient care: a Mohs surgeon's review and perspective (Conference Presentation)

NASA Astrophysics Data System (ADS)

Nehal, Kishwer S.; Rajadhyaksha, Milind

2016-02-01

Latest advances in confocal microscopy of skin cancers toward guiding patient care: a Mohs surgeon's review and perspective About 350 publications worldwide have reported the ability of reflectance confocal microscopy (RCM) imaging to detect melanocytic skin lesions in vivo with specificity of 84-88% and sensitivity of 71-92%, and non-melanocytic skin lesions with specificity of 85-97% and sensitivity 100-92%. Lentigo maligna melanoma can be detected with sensitivity of 93% and specificity 82%. While the sensitivity is comparable to that of dermoscopy, the specificity is 2X superior, especially for lightly- and non-pigmented lesions. Dermoscopy combined with RCM imaging is proving to be both highly sensitive and highly specific. Recent studies have reported that the ratio of equivocal (i.e., would have been biopsied) lesions to detected melanomas dropped by ~2X when guided by dermoscopy and RCM imaging, compared to that with dermoscopy alone. Dermoscopy combined with RCM imaging is now being implemented to guide noninvasive diagnosis (to rule out malignancy and biopsy) and to also guide treatment, with promising initial impact: thus far, about 3,000 patients have been saved from biopsies of benign lesions. These are currently under follow-up monitoring. With fluorescence confocal microscopy (FCM) mosaicing, residual basal cell carcinomas can be detected in Mohs surgically excised fresh tissue ex vivo, with sensitivity of 94-97% and specificity 89-94%. FCM mosaicing is now being implemented for guiding Mohs surgery. To date, about 600 Mohs procedures have been performed, guided with mosaicing, and with pathology being performed in parallel to confirm the final outcome. These latest advances demonstrate the promising ability of RCM and FCM to guide patient care.

A Summary of the NASA Lightning Nitrogen Oxides Model (LNOM) and Recent Results

NASA Technical Reports Server (NTRS)

Koshak, William; Peterson, Harld

2011-01-01

The NASA Marshall Space Flight Center introduced the Lightning Nitrogen Oxides Model (LNOM) a couple of years ago to combine routine state-of-the-art measurements of lightning with empirical laboratory results of lightning NOx production. The routine measurements included VHF lightning source data [such as from the North Alabama Lightning Mapping Array (LMA)], and ground flash location, peak current, and stroke multiplicity data from the National Lightning Detection Network(TradeMark) (NLDN). Following these initial runs of LNOM, the model was updated to include several non-return stroke lightning NOx production mechanisms, and provided the impact of lightning NOx on an August 2006 run of CMAQ. In this study, we review the evolution of the LNOM in greater detail and discuss the model?s latest upgrades and applications. Whereas previous applications were limited to five summer months of data for North Alabama thunderstorms, the most recent LNOM analyses cover several years. The latest statistics of ground and cloud flash NOx production are provided.

Latest R&D news and beam test performance of the highly granular SiW-ECAL technological prototype for the ILC

NASA Astrophysics Data System (ADS)

Irles, A.

2018-02-01

High precision physics at future colliders as the International Linear Collider (ILC) require unprecedented high precision in the determination of the energy of final state particles. The needed precision will be achieved thanks to the Particle Flow algorithms (PF) which require highly granular and hermetic calorimeters systems. The physical proof of concept of the PF was performed in the previous campaign of beam tests of physic prototypes within the CALICE collaboration. One of these prototypes was the physics prototype of the Silicon-Tungsten Electromagnetic Calorimeter (SiW-ECAL) for the ILC. In this document we present the latest news on R&D of the next generation prototype, the technological prototype with fully embedded very front-end (VFE) electronics, of the SiW-ECAL. Special emphasis is given to the presentation and discussion of the first results from the beam test done at DESY in June 2017. The physics program for such beam test consisted in the calibration and commissioning of the current set of available SiW ECAL modules; the test of performance of individual slabs under 1T magnetic fields; and the study of electromagnetic showers events.

A Review of the Application of Body-on-a-Chip for Drug Test and Its Latest Trend of Incorporating Barrier Tissue.

PubMed

Jin, Haoyi; Yu, Yanqiu

2016-10-01

High-quality preclinical bioassay models are essential for drug research and development. We reviewed the emerging body-on-a-chip technology, which serves as a promising model to overcome the limitations of traditional bioassay models, and introduced existing models of body-on-a-chip, their constitutional details, application for drug testing, and individual features of these models. We put special emphasis on the latest trend in this field of incorporating barrier tissue into body-on-a-chip and discussed several remaining challenges of current body-on-a-chip. © 2015 Society for Laboratory Automation and Screening.

New results from RENO & prospects with RENO-50

NASA Astrophysics Data System (ADS)

Joo, K. K.

2017-09-01

This paper briefly describes recent progress of RENO and next generation future prospect of the reactor neutrino oscillation experiment, RENO-50. Recently the RENO experiment has updated its latest value on sin22θ 13 and provided new results on 5 MeV excess, Δm2 ee, θ 13 with n-H analysis, absolute antineutrino flux measurement, and sterile neutrino search. It gives rich programs of neutrino properties, detector development, nuclear monitoring and application. Using reactor neutrinos, the future RENO-50 experiment will search for more precise measurement of θ 12, Δm 2 12 and mass hierarchy.

Latest Pleistocene glaciomarine and marine deposition in the northern Puget lowland, Washington

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dethier, D.P.

Latest Pleistocene (Fraser) continental ice deposited thick, narrow zones of ice-marginal debris and widespread pebbly silt into marine water as it retreated from the northern Puget lowland of Washington at about 14,000 B.P. Exposed deposits include several collapsed terrestrial ice-contact complexes. Most sediment accumulated in marine water during or after ice retreat, but before glacioisostatic rebound lifted the area about sea level. Gravelly sand, pebbly silt, gravelly diamicton, cross bedded silty sand, and massive to laminated silt were deposited in glaciomarine, marine, estuarine, and shoreline environments now exposed at elevations as high as 150 m. Ice-proximal facies formed from sediment-richmore » fresh-water plumes and mass movements at the margins of grounded ice lobes; transitional and distal deposits incorporated sediment from dispersed meltwater, turbidity flows and icebergs hundreds of m to tens of km from the grounding line. Macrofossils assemblages in the glaciomarine deposits formed in water < 40 meters deep whereas the marine deposits represent intertidal depths to over 80 meters. [sup 14]C shell ages demonstrate that ice retreated 125 km from the E. Strait of Juan de Fuca between about 14.0 ka and 13.5 ka, and that a fluctuating ice margin persisted near the international Border until sometime after 11.5 ka. More than 10 km[sup 3] of ice-marginal sediment, now bands of submerged banks, outline grounding-line positions in the 50 km between the E. Strait of Juan de Fuca and the San Juan Islands.« less

77 FR 14002 - Stainless Steel Butt-Weld Pipe Fittings From Italy, Malaysia, and the Philippines: Final Results...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-08

... steel fittings of seamless and welded construction covered by the latest revision of ANSI B16.9, ANSI...] Stainless Steel Butt-Weld Pipe Fittings From Italy, Malaysia, and the Philippines: Final Results of the... Commerce (the Department) initiated sunset reviews of the antidumping duty orders on stainless steel butt...

Latest Pleistocene to Holocene hydroclimates from Lake Elsinore, California

NASA Astrophysics Data System (ADS)

Kirby, Matthew E.; Feakins, Sarah J.; Bonuso, Nicole; Fantozzi, Joanna M.; Hiner, Christine A.

2013-09-01

The hydroclimate of the southwestern United States (US) region changed abruptly during the latest Pleistocene as the continental ice sheets over North America retreated from their most southerly extent. To investigate the nature of this change, we present a new record from Lake Elsinore, located 36 km inland from the Pacific Ocean in Southern California and evaluate it in the context of records across the coastal and interior southwest United States, including northwest Mexico. The sediment core recovered from Lake Elsinore provides a continuous sequence with multi-decadal resolution spanning 19-9 ka BP. Sedimentological and geochemical analyses reveal hydrologic variability. In particular, sand and carbonate components indicate abrupt changes at the Oldest Dryas (OD), Bølling-Allerød (BA), and Younger Dryas (YD) transitions, consistent with the timing in Greenland. Hydrogen isotope analyses of the C28n-alkanoic acids from plant leaf waxes (δDwax) reveal a long term trend toward less negative values across 19-9 ka BP. δDwax values during the OD suggest a North Pacific moisture source for precipitation, consistent with the dipping westerlies hypothesis. We find no isotopic evidence for the North American Monsoon reaching as far west as Lake Elsinore; therefore, we infer that wet/dry changes in the coastal southwest were expressed through winter-season precipitation, consistent with modern climatology. Comparing Lake Elsinore to other southwest records (notably Cave of Bells and Fort Stanton) we find coincident timing of the major transitions (OD to BA, BA to YD) and hydrologic responses during the OD and BA. The hydrologic response, however, varied during the YD consistent with a dipole between the coastal and interior southwest. The coherent pattern of hydrologic responses across the interior southwest US and northwest Mexico during the OD (wet), the BA (drier), and YD (wet) follows changes in the Atlantic Meridional Overturning Circulation, presumably via its

Latest Developments on Obtaining Accurate Measurements with Pitot Tubes in ZPG Turbulent Boundary Layers

NASA Astrophysics Data System (ADS)

Nagib, Hassan; Vinuesa, Ricardo

2013-11-01

Ability of available Pitot tube corrections to provide accurate mean velocity profiles in ZPG boundary layers is re-examined following the recent work by Bailey et al. Measurements by Bailey et al., carried out with probes of diameters ranging from 0.2 to 1.89 mm, together with new data taken with larger diameters up to 12.82 mm, show deviations with respect to available high-quality datasets and hot-wire measurements in the same Reynolds number range. These deviations are significant in the buffer region around y+ = 30 - 40 , and lead to disagreement in the von Kármán coefficient κ extracted from profiles. New forms for shear, near-wall and turbulence corrections are proposed, highlighting the importance of the latest one. Improved agreement in mean velocity profiles is obtained with new forms, where shear and near-wall corrections contribute with around 85%, and remaining 15% of the total correction comes from turbulence correction. Finally, available algorithms to correct wall position in profile measurements of wall-bounded flows are tested, using as benchmark the corrected Pitot measurements with artificially simulated probe shifts and blockage effects. We develop a new scheme, κB - Musker, which is able to accurately locate wall position.

Volcanic Debris Flows of the Latest Paleozoic Arbasay Formation: Geomorphological Characters and Paleoenvironment Reconstruction of Northern Tian Shan, NW China

NASA Astrophysics Data System (ADS)

Yang, W.; Liu, D.; Guo, Z.

2015-12-01

Texturally well-preserved volcanic debris flows (also called lahars) are exposed in the Latest Paleozoic Arbasay Formation, Northern Tian Shan. LA-ICP-MS zircon dating of the intercalated fallout tuff sample provided an age of 314.4±3.4 Ma (MSWD=1.6), suggesting they were deposited at Latest Carboniferous. The lahars consist primarily of two lithofacies: massive, poorly lithified diamictites and stratified, moderately lithified gravelly sandstones. The diamictites can be generally divided into two subfacies, i.e., the matrix-supported and the clast-supported diamictites. Most diamictites are structureless and nongraded. They are thick in beds and contain large clasts up to 3 m in dimension. The gravelly sandstones display much finer particle size and have wedge or lenticular geometries. Large clasts are absent within them and the sorting characters are much better than the diamictites. Despite the different size grading, the matrix and the clasts of the two lithofacies appear to be homogeneous. The matrix is generally sandy mudstone. The clasts comprise rhyolites, dacites, andesites, andesitic basalts and basalts, same to the co-existing volcanic rocks, suggesting they originate from the cognate volcanics. The disorganized diamictites are supposed to deposit from a turbulent flood or pyroclastic surge. The gravelly sandstone lithofacies are interpreted as sand-rich flood flows or hyperconcentrated flood flows during the waning stage of a mass-flow event. The overall characteristics of the deposits suggest a mass-flow dominated alluvial fan environment. It's noteable that several syn- sedimentary normal faults occurred within these lahar deposits, indicating that the Southern Junggar Basin was in an extensional regime during the lahars' deposition. Structure is dominated by normal faulting, allowing the existence of relatively small, highly compartmentalized depocenters. This is also supported by geochemistry and detrital zircon studies.

Results from the NOvA Experiment

NASA Astrophysics Data System (ADS)

Smith, Erica

The NOvA experiment is a long-baseline accelerator-based neutrino oscillation experiment. It uses the upgraded NuMI beam from Fermilab to measure electron-neutrino appearance and muon-neutrino disappearance between the Near Detector, located at Fermilab, and the Far Detector, located at Ash River, Minnesota. The NuMI beam has recently reached and surpassed the 700 kW power benchmark. NOvA’s primary physics goals include precision measurements of oscillation parameters, such as 𝜃23 and the atmospheric mass-squared splitting, along with probes of the mass hierarchy and of the CP violating phase. This talk will present the latest NOvA results, based on a neutrino beam exposure equivalent to 6.05 × 1020 protons-on-target.

Latest research related to climate change analysis with applications in impact studies over the territory of Serbia

NASA Astrophysics Data System (ADS)

Vukovic, Ana; Vujadinovic, Mirjam; Djurdjevic, Vladimir; Cvetkovic, Bojan; Djordjevic, Marija; Ruml, Mirjana; Rankovic-Vasic, Zorica; Przic, Zoran; Stojicic, Djurdja; Krzic, Aleksandra; Rajkovic, Borivoj

2015-04-01

Serbia is a country with relatively small scale terrain features with economy mostly based on local landowners' agricultural production. Climate change analysis must be downscaled accordingly, to recognize climatological features of the farmlands. Climate model simulations and impact studies significantly contribute to the future strategic planning in economic development and therefore impact analysis must be approached with high level of confidence. This paper includes research related to climate change and impacts in Serbia resulted from cooperative work of the modeling and user community. Dynamical downscaling of climate projections for the 21st century with multi-model approach and statistical bias correction are done in order to prepare model results for impact studies. Presented results are from simulations performed using regional EBU-POM model, which is forced with A1B and A2 SRES/IPCC (2007) with comparative analysis with other regional models and from the latest high resolution NMMB simulations forced with RCP8.5 IPCC scenario (2012). Application of bias correction of the model results is necessary when calculated indices are not linearly dependent on the model results and delta approach in presenting results with respect to present climate simulations is insufficient. This is most important during the summer over the north part of the country where model bias produce much higher temperatures and less precipitation, which is known as "summer drying problem" and is common in regional models' simulations over the Pannonian valley. Some of the results, which are already observed in present climate, like higher temperatures and disturbance in the precipitation pattern, lead to present and future advancement of the start of the vegetation period toward earlier dates, associated with an increased risk of the late spring frost, extended vegetation period, disturbed preparation for the rest period, increased duration and frequency of the draught periods, etc

Development of an Efficient Identifier for Nuclear Power Plant Transients Based on Latest Advances of Error Back-Propagation Learning Algorithm

NASA Astrophysics Data System (ADS)

Moshkbar-Bakhshayesh, Khalil; Ghofrani, Mohammad B.

2014-02-01

This study aims to improve the performance of nuclear power plants (NPPs) transients training and identification using the latest advances of error back-propagation (EBP) learning algorithm. To this end, elements of EBP, including input data, initial weights, learning rate, cost function, activation function, and weights updating procedure are investigated and an efficient neural network is developed. Usefulness of modular networks is also examined and appropriate identifiers, one for each transient, are employed. Furthermore, the effect of transient type on transient identifier performance is illustrated. Subsequently, the developed transient identifier is applied to Bushehr nuclear power plant (BNPP). Seven types of the plant events are probed to analyze the ability of the proposed identifier. The results reveal that identification occurs very early with only five plant variables, whilst in the previous studies a larger number of variables (typically 15 to 20) were required. Modular networks facilitated identification due to its sole dependency on the sign of each network output signal. Fast training of input patterns, extendibility for identification of more transients and reduction of false identification are other advantageous of the proposed identifier. Finally, the balance between the correct answer to the trained transients (memorization) and reasonable response to the test transients (generalization) is improved, meeting one of the primary design criteria of identifiers.

Latest Results from and Plans for the New Horizons Pluto-Kuiper Belt Mission

NASA Astrophysics Data System (ADS)

Weaver, Harold; Stern, Alan

2016-07-01

On 2015 July 14 NASA's New Horizons spacecraft flew 12,500 km above the surface of Pluto revealing a world of remarkable complexity and diversity. A giant basin filled with nitrogen ice dominated the encounter hemisphere and is the site of vigorous ongoing solid state convection that generates glacier-like transport along the surface. Giant mountains of water ice appear to be floating in the nitrogen ice. The periphery of the basin has a wide variety of landforms, including ice flow channels and chaotically arranged blocks of water ice. Extensive sublimation pitting is observed within the nitrogen ice sheet, testifying to active volatile transport. Peculiar bladed terrain to the east of the nitrogen ice sheet appears to be coated by methane ice. Pluto's equatorial region is dominated by an ancient dark red belt of material, probably tholins created either by irradiation of surface ices or by haze precipitation from the atmosphere. Pluto sports a wide variety of surface craters with some terrains dating back approximately 4 billion years while some terrains are geologically young. New Horizons discovered trace hydrocarbons in Pluto's atmosphere, multiple global haze layers, and a surface pressure near 10 microbars. Charon, Pluto's largest moon, displays tectonics, evidence for a heterogeneous crustal composition, and a puzzling giant hood of dark material covering its North Pole. Crater density statistics for Charon's surface give a crater retention age of 4-4.5 Ga, indicating that Charon's geological evolution largely ceased early in its history. All of Pluto's four small moons (Styx, Nix, Kerberos, and Hydra) have high albedos, highly elongated shapes, and are rotating much faster then synchronous with their orbital periods, with rotational poles clustered near the Pluto-Charon orbital plane. The surfaces of Nix and Hydra are coated with nearly pristine crystalline water ice, despite having crater retention ages greater than 4 billion years. The New Horizons spacecraft remains healthy and was targeted toward the flyby of a small (~30-40 km) KBO in late-2015, enabling the study of an object (2014 MU69) in a completely different dynamical class (cold classical) than Pluto, if NASA approves an Extended Mission phase. In addition to the flyby of 2014 MU69 on 2019-Jan-01, the proposed Extended Mission would also include observations of more than 20 other KBOs at resolutions and geometries not feasible from Earth, and studies of the heliospheric plasma, neutral H and He, and the dust environment out to 50 AU from the Sun.

Ground-based Efforts to Support a Space-Based Experiment: the Latest LADEE Results

NASA Astrophysics Data System (ADS)

Cudnik, Brian; Rahman, Mahmudur

2014-05-01

The much anticipated launch of the Lunar Atmosphere and Dust Environment Explorer happened flawlessly last October and the satellite has been doing science (and sending a few images) since late November. [the LADEE mission ended with the crash-landing of the spacecraft on the lunar far side on April 17, 2014, capping a successful 140 day mission] .We also have launched our campaign to document lunar meteoroid impact flashes from the ground to supply ground truth to inform of any changes in dust concentration encountered by the spacecraft in orbit around the moon. To date I have received six reports of impact flashes or flash candidates from the group I am coordinating; other groups around the world may have more to add when all is said and done. In addition, plans are underway to prepare a program at Prairie View A&M University to involve our physics majors in lunar meteoroid, asteroid occultation, and other astronomical work through our Center for Astronomical Sciences and Technology. This facility will be a control center to not only involve physics majors, but also to include pre-service teachers and member of the outside community to promote pro-am collaborations.

Beryllium for fusion application - recent results

NASA Astrophysics Data System (ADS)

Khomutov, A.; Barabash, V.; Chakin, V.; Chernov, V.; Davydov, D.; Gorokhov, V.; Kawamura, H.; Kolbasov, B.; Kupriyanov, I.; Longhurst, G.; Scaffidi-Argentina, F.; Shestakov, V.

2002-12-01

The main issues for the application of beryllium in fusion reactors are analyzed taking into account the latest results since the ICFRM-9 (Colorado, USA, October 1999) and presented at 5th IEA Be Workshop (10-12 October 2001, Moscow Russia). Considerable progress has been made recently in understanding the problems connected with the selection of the beryllium grades for different applications, characterization of the beryllium at relevant operational conditions (irradiation effects, thermal fatigue, etc.), and development of required manufacturing technologies. The key remaining problems related to the application of beryllium as an armour in near-term fusion reactors (e.g. ITER) are discussed. The features of the application of beryllium and beryllides as a neutron multiplier in the breeder blanket for power reactors (e.g. DEMO) in pebble-bed form are described.

High sedimentation rates in the Early Triassic after latest Permian mass extinction: Carbonate production is main factor in non-Arctic regions

NASA Astrophysics Data System (ADS)

Horacek, Micha; Brandner, Rainer

2016-04-01

A substantial change in sedimentation rates towards higher values has been documented from the Late Permian to the Lower Triassic. Although it is assumed and also has been shown that the deposition of siliciclastic material increased in the Lower Triassic due to stronger erosion because of loss of land cover and increased chemical and physical weathering with extreme climate warming, the main sediment production occurred by marine carbonate production. Still, carbonate production might have been significantly influenced by weathering and erosion in the hinterland, as the transport of dust by storms into the ocean water probably was a main nutrient source for microbial carbonate producers, because "normal" nutrient supply by ocean circulation, i. e. upwelling was strongly reduced due to the elevated temperatures resulting in water-column stratification . Sediment accumulation was also clearly influenced by the paleo-geographic and latitudinal position, with lower carbonate production and sedimentation rates in moderate latitudes. The existence of a "boundary clay" and microbial carbonate mounds and layers in the immediate aftermath of the latest Permian mass extinction points towards a development from a short-timed acid ocean water - resulting in a carbonate production gap and the deposition of the boundary clay towards the deposition of the microbial mounds and layers due to the microbial production of micro-environments with higher alkalinity allowing the production of carbonate. After the return of the ocean water to normal alkalinity planktic production of carbonate resulted in a very high sedimentation rate, especially taking into account the absence of carbonate producing eukaryotic algae and animals.

ActiWiz 3 – an overview of the latest developments and their application

NASA Astrophysics Data System (ADS)

Vincke, H.; Theis, C.

2018-06-01

In 2011 the ActiWiz code was developed at CERN in order to optimize the choice of materials for accelerator equipment from a radiological point of view. Since then the code has been extended to allow for calculating complete nuclide inventories and provide evaluations with respect to radiotoxicity, inhalation doses, etc. Until now the software included only pre-defined radiation environments for CERN’s high-energy proton accelerators which were based on FLUKA Monte Carlo calculations. Eventually the decision was taken to invest into a major revamping of the code. Starting with version 3 the software is not limited anymore to pre-defined radiation fields but within a few seconds it can also treat arbitrary environments of which fluence spectra are available. This has become possible due to the use of ~100 CPU years’ worth of FLUKA Monte Carlo simulations as well as the JEFF cross-section library for neutrons < 20 MeV. Eventually the latest code version allowed for the efficient inclusion of 42 additional radiation environments of the LHC experiments as well as considerably more flexibility in view of characterizing also waste from CERN’s Large Electron Positron collider (LEP). New fully integrated analysis functionalities like automatic evaluation of difficult-to-measure nuclides, rapid assessment of the temporal evolution of quantities like radiotoxicity or dose-rates, etc. make the software a powerful tool for characterization complementary to general purpose MC codes like FLUKA. In this paper an overview of the capabilities will be given using recent examples from the domain of waste characterization as well as operational radiation protection.

Chemical sensors for breath gas analysis: the latest developments at the Breath Analysis Summit 2013.

PubMed

Tisch, Ulrike; Haick, Hossam

2014-06-01

Profiling the body chemistry by means of volatile organic compounds (VOCs) in the breath opens exciting new avenues in medical diagnostics. Gas sensors could provide ideal platforms for realizing portable, hand-held breath testing devices in the near future. This review summarizes the latest developments and applications in the field of chemical sensors for diagnostic breath testing that were presented at the Breath Analysis Summit 2013 in Wallerfangen, Germany. Considerable progress has been made towards clinically applicable breath testing devices, especially by utilizing chemo-sensitive nanomaterials. Examples of several specialized breath testing applications are presented that are either based on stand-alone nanomaterial-based sensors being highly sensitive and specific to individual breath compounds over others, or on combinations of several highly specific sensors, or on experimental nanomaterial-based sensors arrays. Other interesting approaches include the adaption of a commercially available MOx-based sensor array to indirect breath testing applications, using a sample pre-concentration method, and the development of compact integrated GC-sensor systems. The recent trend towards device integration has led to the development of fully integrated prototypes of point-of-care devices. We describe and compare the performance of several prototypes that are based on different sensing technologies and evaluate their potential as low-cost and readily available next-generation medical devices.

Baseline asynchrony, assessed circumferentially using temporal uniformity of strain, besides coincidence between site of latest mechanical activation and presumed left ventricular lead position, predicts favourable prognosis after resynchronization therapy.

PubMed

Cavallino, Chiara; Rondano, Elisa; Magnani, Andrea; Leva, Lucia; Inglese, Eugenio; Dell'era, Gabriele; Occhetta, Eraldo; Bortnik, Miriam; Marino, Paolo N

2012-06-01

Traditional indexes of LV dyssynchrony (DYS) in pts to be resynchronized are sensitive to noise, while the concordance between LV lead position and site of latest mechanical activation is suggested to be, in these patients, clinically relevant. Both aspects, asynchrony and lead position have been addressed separately but unclear is their potential synergistic role in the clinical evolution of CRT patients. We assessed clinical and echocardiographic outcome, as well as mid-term prognosis, in a population of CHF patients submitted to CRT, stratified according to a novel asynchrony quantitation (temporal uniformity of strain: TUS) method and concordance or not between presumed LV lead position and site of latest mechanical activation. TUS was computed in 85 pts (QRS > 120 ms, EF < 0.35) in whom we measured circumferential and longitudinal strains using speckle-tracking 2D-echocardiography before and 3-6 months after CRT, together with triplane apical LV volumes. Optimal LV lead position in short axis view was defined as concordance of the segment with latest systolic circumferential strain prior-CRT and segment with assumed LV lead position. Assumed LV lead position was defined from a chest X-ray obtained 1 day after implantation and scored as anterior, lateral, posterior or inferior using 2 orthogonal views (antero-posterior and lateral). Following CRT, LV volume decreased (diastolic -8 ± 20%) and EF improved (+6 ± 9%, P < 0.001 for both). Two-way ANOVA revealed TUS improvement post-CRT (+22 ± 68%, P = 0.025), with a clear evidence for more marked asynchrony detectable at circumferential (from 0.53 ± 0.20 to 0.55 ± 0.19) as compared with longitudinal level (from 0.56 ± 0.14 to 0.62 ± 0.14) (P = 0.017). Multivariate analysis revealed that greater baseline asynchrony, as assessed circumferentially (P = 0.079), together with concordance between LV lead position and site of activation (P = 0.012), besides younger age (P = 0.051), longer QRS duration (P = 0

A Pelican Tarsometatarsus (Aves: Pelecanidae) from the Latest Pliocene Siwaliks of India

PubMed Central

Stidham, Thomas A.; Krishan, Kewal; Singh, Bahadur; Ghosh, Abhik; Patnaik, Rajeev

2014-01-01

We report a new fossil specimen of a pelican from the Tatrot Formation of the Siwalik Hills, India. It likely represents Pelecanus sivalensis Davies, 1880, the smaller of the two previously published species from the Siwalik Group stratigraphic sequence. This complete tarsometatarsus is the first fossil bone of a pelican collected in India for over 100 years. It is from the latest Pliocene (∼2.6 Ma), and is the youngest pelican fossil from the region. The new specimen exhibits a derived distoplantar ‘slant’ to the plantar margin of the medial crest of the hypotarsus, and a combination of features related to the morphology of the hypotarsus, the distal foramen, trochleae, and overall size that allow further differentiation from known tarsometatarsi of fossil and extant pelicans, including the three species of extant pelicans that occur in India (Pelecanus crispus, P. onocrotalus, and P. philippensis). It is of appropriate size for Pelecanus sivalensis, which to date has been known only by fragments of other skeletal elements of the wing, leg, and shoulder girdle. Thus, the observation that this tarsometatarsus is morphologically distinct from those of known pelicans provides further support for the distinctiveness of at least one extinct species of pelican from the Siwalik Group sediments. While the morphology of the tarsometatarsus allows for separation from other taxa known from tarsometatarsi, we found no clear shared derived states to place this taxon with any confidence in a phylogenetic context relative to any other pelican species, or even determine if it is part of the crown group of Pelecanidae. However, published molecular data are consistent with an origin of the crown clade prior to the Pleistocene, suggesting (along with one morphological character) the possibility that this species belongs to the Old World clade of pelican species. PMID:25365300

Cosmogenic 10Be Dating of Early and Latest Holocene Moraines on Nevado Salcantay in the Southern Peruvian Andes

NASA Astrophysics Data System (ADS)

Licciardi, J. M.; Schaefer, J. M.; Lund, D. C.

2007-12-01

A two-fold sequence of nested lateral and end moraines was mapped in a glacial trough emanating from the southwest flank of Nevado Salcantay (6271 m; ~13°S latitude), the highest peak in the Cordillera Vilcabamba of southern Peru. The field area is situated 25 km due south of the archaeological site of Machu Picchu. Outer and inner moraines in the sequence were deposited by valley glaciers that terminated ~5 km and ~3 km, respectively, from their headwall on the Salcantay summit massif. Cosmogenic 10Be surface exposure dating of granitic boulders sampled on the Salcantay moraines is underway and has provided the first numerical ages for these deposits. Initial results indicate ages of 8.1 ± 0.1 10Be ka for the outer moraine and 200 ± 20 10Be years for the sharp-crested inner moraine. These ages are derived using the CRONUS-Earth 10Be exposure age calculator (version 2.0) and expressed with respect to the Lal- Stone production rate scaling scheme using the standard atmosphere. The outer and inner moraine ages correspond to glacial events during the early and latest Holocene, respectively. Further 10Be dating of the mapped moraines and similar deposits observed in adjacent drainages on Nevado Salcantay is anticipated to yield a high-resolution chronology of valley glaciation in this segment of the southern Peruvian Andes. The new results bridge an important gap between existing Andean glacier records to the north and south, and complement available ice core and lacustrine paleoclimate records in the vicinity, thereby expanding spatial and temporal coverage for identifying patterns of Holocene climate change in the tropical Andes. Notably, the inner moraine age correlates with the timing of the Little Ice Age as defined in northern mid- and high latitude glacier records, and suggests considerable expansion of valley glaciers in the southern Peruvian Andes during this climatic minimum. Apart from their paleoclimatic significance, the initial results also demonstrate

Experimental approach to measure thick target neutron yields induced by heavy ions for shielding

NASA Astrophysics Data System (ADS)

Trinh, N. D.; Fadil, M.; Lewitowicz, M.; Brouillard, C.; Clerc, T.; Damoy, S.; Desmezières, V.; Dessay, E.; Dupuis, M.; Grinyer, G. F.; Grinyer, J.; Jacquot, B.; Ledoux, X.; Madeline, A.; Menard, N.; Michel, M.; Morel, V.; Porée, F.; Rannou, B.; Savalle, A.

2017-09-01

Double differential (angular and energy) neutron distributions were measured using an activation foil technique. Reactions were induced by impinging two low-energy heavy-ion beams accelerated with the GANIL CSS1 cyclotron: (36S (12 MeV/u) and 208Pb (6.25 MeV/u)) onto thick natCu targets. Results have been compared to Monte-Carlo calculations from two codes (PHITS and FLUKA) for the purpose of benchmarking radiation protection and shielding requirements. This comparison suggests a disagreement between calculations and experiment, particularly for high-energy neutrons.

[Latest trends in the surgical management of mandibular condyle fractures in France, 2005-2012].

PubMed

Trost, O; Péron, J-M

2013-12-01

The surgical treatment of mandibular condylar fractures is commonly performed. We had for aim to present the latest trends in the surgical management of condylar fractures in France, between 2005 and 2012. A survey was performed among the 49 members of the French college of oral and maxillofacial surgeons between January and September 2012, with a questionnaire sent by email. We analyzed the therapeutic management, the surgical indications; the techniques used according to the fracture, and the postoperative treatment protocols. The data was compared to that of a similar study performed in 2005. The overall reply rate was 86%. Low subcondylar fractures were operated on in all institutions (100%), compared to 76% in 2005. The most popular technique was the high submandibular approach with intraoral miniplate fixation osteosynthesis. High subcondylar and diacapitular fractures were operated on in respectively 82% and 35% of the cases compared to 29% and 10% in 2005 with various surgical techniques and postoperative management. French maxillofacial surgeons operated on more mandibular condylar fractures in 2012 than in 2005. As observed in 2005, the lower and the more dislocated the fractures were, the more they were operated on. The high submandibular approach has become the most popular approach. The use of miniplates for bone fixation has become common. Diacapitular fractures were usually treated functionally. The postoperative management varied greatly from one team to the other. Copyright © 2013. Published by Elsevier Masson SAS.

The European ruminants during the "Microbunodon Event" (MP28, Latest Oligocene): impact of climate changes and faunal event on the ruminant evolution.

PubMed

Mennecart, Bastien

2015-01-01

The Earth already experienced numerous episodes of global warming and cooling. One of the latest impressive events of temperature rising was the Late Oligocene Warming that occurred around 25 Mya. An increase of the marine temperature of 2 to 4°C has been observed in a short time interval. In Europe, this major climatic event can be correlated to the continental faunal turnover "Microbunodon Event". This event is marked by a huge faunal turnover (40% of the ungulate fauna during the first 500k years) and environmental changes. Drier conditions associated to the appearance of the seasonality lead to new environmental conditions dominated by wooded savannahs. This is correlated to a major arrival of Asiatic immigrants. Moreover, from a homogenous fauna during the main part of the Oligocene, local climatic variations between the European Western coast and the more central Europe could have provided faunal regionalism during the latest Oligocene and earliest Miocene. Considering the ruminants, this event is the major ever known for this group in Europe. A total renewal at the family level occurred. Thanks to a precise stratigraphic succession, major evolutionary elements are highlighted. Typical Oligocene species, mainly Tragulina, were adapted to wooded environments and were leaves/fruits eaters. They disappeared at the end of MP27 or the early MP28. This corresponds to the appearance of the Asiatic immigrants. The Tragulina (Lophiomerycidae, Bachitheriidae) and stem Pecora gave way to more derived stem and maybe crown Pecora (e.g. "Amphitragulus", Babameryx, Dremotherium). These newcomers were adapted to more open environments and mixed feeding. The disappearance of the Tragulina is probably linked to environmental and vegetation changes, and competition. They give way to more derived ruminants having a more efficient metabolism in drier conditions and a better assimilation of less energetic food.

Dual-readout calorimetry: recent results from RD52 and plans for experiments at future e+e- colliders

NASA Astrophysics Data System (ADS)

Ferrari, R.

2018-02-01

The Dual-Readout calorimetry, developed to overcome the main limiting factor in hadronic energy measurements, has been thoroughly investigated by the DREAM/RD52 collaboration during the last 15 years. The latest results show that very interesting performance may be obtained for both e.m. and hadronic showers, together with excellent standalone e/pi separation. These results and the plans (and the expected performance) for dual-readout calorimetry in the CepC/FCC-ee environment, are presented and discussed.

Recent Results from the Daya Bay Experiment

NASA Astrophysics Data System (ADS)

Yu, Z. Y.; Daya Bay Collaboration

2017-09-01

The Daya Bay reactor neutrino experiment was designed to precisely measure the neutrino oscillation parameter θ 13 via the relative comparison of neutrino rates and spectra at different baselines. Eight identically designed detectors were deployed in two near experimental halls and a far hall. Six 2.9 GWth nuclear power reactors served as intense {\\bar ν _e} sources. Since Dec. 2011, the experiment has been running stably. The latest neutrino oscillation results were based on 1230 days of data. Analysis using a three-flavor oscillation model yielded sin22θ 13 = 0.0841 ± 0.0027(stat.) ± 0.0019(syst.), and effective neutrino mass-squared difference ≤ft| {Δ mee^2} \\right| = ≤ft( {2.50 +/- 0.06≤ft( {stat.} \\right) +/- 0.06≤ft( {syst.} \\right)} \\right) × {10 - 3}e{V^2}. Besides, results from the absolute measurement of reactor {\\bar ν _e} flux and energy spectrum, and a search for a light sterile neutrino are also presented.

Coastal eolian sand-ramp development related to paleo-sea-level changes during the Latest Pleistocene and Holocene (21–0 ka) in San Miguel Island, California, U.S.A.

USGS Publications Warehouse

Peterson, Curt D.; Erlandson, Jon M.; Stock, Errol; Hostetler, Steven W.; Price, David M.

2017-01-01

Coastal eolian sand ramps (5–130 m elevation) on the northern slope (windward) side of the small San Miguel Island (13 km in W-E length) range in age from late Pleistocene to modern time, though a major hiatus in sand-ramp growth occurred during the early Holocene marine transgression (16–9 ka). The Holocene sand ramps (1–5 m measured thicknesses) currently lack large dune forms, thereby representing deflated erosional remnants, locally covering thicker late Pleistocene sand-ramp deposits. The ramp sand was initially supplied from the adjacent island-shelf platform, extending about 20 km north of the present coastline. The sand-ramp deposits and interbedded loess soils were 14C dated using 112 samples from 32 archaeological sites and other geologic sections. Latest Pleistocene sand ramps (66–18 ka) were derived from across-shelf eolian sand transport during marine low stands. Shoreward wave transport supplied remobilized late Pleistocene sand from the inner shelf to Holocene beaches, where dominant NW winds supplied sand to the sand ramps. The onset dates of the sand-ramp deposition in San Miguel are 7.2 ± 1.5 ka (sample n = 14). The internal strata dates in the vertically accreting sand ramps are 3.4 ± 1.7 ka (n = 34). The sand ramps in San Miguel show wide-scale termination of sand supply in the latest Holocene time. The sand-ramp top dates or burial dates are 1.7 ± 0.9 ka (n = 28). The latest Holocene sand ramps are truncated along most of the island's northern coastline, indicating recent losses of nearshore sand reserves to onshore, alongshore, and, possibly, offshore sand sinks. The truncated sand ramps in San Miguel Island and in other sand-depleted marine coastlines provide warnings about future beach erosion and/or shoreline retreat from accelerated sea-level rise accompanying predicted global warming.

Latest Pleistocene and Holocene glacial events in the Colonia valley, Northern Patagonia Icefield, southern Chile

USGS Publications Warehouse

Nimick, David A.; Mcgrath, Daniel; Mahan, Shannon; Friesen, Beverly A.; Leidich, Jonathan

2016-01-01

The Northern Patagonia Icefield (NPI) is the primary glaciated terrain worldwide at its latitude (46.5–47.5°S), and constraining its glacial history provides unique information for reconstructing Southern Hemisphere paleoclimate. The Colonia Glacier is the largest outlet glacier draining the eastern NPI. Ages were determined using dendrochronology, lichenometry, radiocarbon, cosmogenic 10Be and optically stimulated luminescence. Dated moraines in the Colonia valley defined advances at 13.2 ± 0.95, 11.0 ± 0.47 and 4.96 ± 0.21 ka, with the last being the first constraint on the onset of Neoglaciation for the eastern NPI from a directly dated landform. Dating in the tributary Cachet valley, which contains an ice-dammed lake during periods of Colonia Glacier expansion, defined an advance at ca. 2.95 ± 0.21 ka, periods of advancement at 810 ± 49 cal a BP and 245 ± 13 cal a BP, and retreat during the intervening periods. Recent Colonia Glacier thinning, which began in the late 1800s, opened a lower-elevation outlet channel for Lago Cachet Dos in ca. 1960. Our data provide the most comprehensive set of Latest Pleistocene and Holocene ages for a single NPI outlet glacier and expand previously developed NPI glacial chronologies.

Latest Results on Complex Plasmas with the PK-3 Plus Laboratory on Board the International Space Station

NASA Astrophysics Data System (ADS)

Schwabe, M.; Du, C.-R.; Huber, P.; Lipaev, A. M.; Molotkov, V. I.; Naumkin, V. N.; Zhdanov, S. K.; Zhukhovitskii, D. I.; Fortov, V. E.; Thomas, H. M.

2018-03-01

Complex plasmas are low temperature plasmas that contain microparticles in addition to ions, electrons, and neutral particles. The microparticles acquire high charges, interact with each other and can be considered as model particles for effects in classical condensed matter systems, such as crystallization and fluid dynamics. In contrast to atoms in ordinary systems, their movement can be traced on the most basic level, that of individual particles. In order to avoid disturbances caused by gravity, experiments on complex plasmas are often performed under microgravity conditions. The PK-3 Plus Laboratory was operated on board the International Space Station from 2006 - 2013. Its heart consisted of a capacitively coupled radio-frequency plasma chamber. Microparticles were inserted into the low-temperature plasma, forming large, homogeneous complex plasma clouds. Here, we review the results obtained with recent analyzes of PK-3 Plus data: We study the formation of crystallization fronts, as well as the microparticle motion in, and structure of crystalline complex plasmas. We investigate fluid effects such as wave transmission across an interface, and the development of the energy spectra during the onset of turbulent microparticle movement. We explore how abnormal particles move through, and how macroscopic spheres interact with the microparticle cloud. These examples demonstrate the versatility of the PK-3 Plus Laboratory.

Social Security reform: evaluating current proposals. Latest results of the EBRI-SSASIM2 policy simulation model.

PubMed

Copeland, C; VanDerhei, J; Salisbury, D L

1999-06-01

save the 2 percent of their OASDI taxable income or to receive higher takehome pay, as would be allowed in Moynihan/Kerrey, could lead to substantial differences in ultimate retirement income. Allowing for individual investment choices and using actual 401(k) participant allocation data, as opposed to an assumed average allocation for everyone, results in substantial differences in account balances. The Archer/Shaw approach mandates a 60 percent/40 percent equity/bond split specifically to avoid the variations in returns that arise from individual investment allocation decisions. Although there are greater chances for higher returns for equity investment in the president's proposal, there are also greater chances for worse outcomes. This is also true for other reforms that would invest Social Security assets in equities.

Advances in Multi-Pixel Photon Counter technology: First characterization results

NASA Astrophysics Data System (ADS)

Bonanno, G.; Marano, D.; Romeo, G.; Garozzo, S.; Grillo, A.; Timpanaro, M. C.; Catalano, O.; Giarrusso, S.; Impiombato, D.; La Rosa, G.; Sottile, G.

2016-01-01

Due to the recent advances in silicon photomultiplier technology, new types of Silicon Photomultiplier (SiPM), also named Multi-Pixel Photon Counter (MPPC) detectors have become recently available, demonstrating superior performance in terms of their most important electrical and optical parameters. This paper presents the latest characterization results of the novel Low Cross-Talk (LCT) MPPC families from Hamamatsu, where a noticeable fill-factor enhancement and cross-talk reduction is achieved. In addition, the newly adopted resin coating has been proven to yield improved photon detection capabilities in the 280-320 nm spectral range, making the new LCT MPPCs particularly suitable for emerging applications like Cherenkov Telescope Array, and Astroparticle Physics.

LOPES — Recent Results and Open Questions on the Radio Detection of Air Showers

NASA Astrophysics Data System (ADS)

Schröder, F. G.; Apel, W. D.; Arteaga-Velázquez, J. C.; Bähren, L.; Bekk, K.; Bertaina, M.; Biermann, P. L.; Blümer, J.; Bozdog, H.; Brancus, I. M.; Cantoni, E.; Chiavassa, A.; Daumiller, K.; de Souza, V.; Di Pierro, F.; Doll, P.; Engel, R.; Falcke, H.; Fuchs, B.; Gemmeke, H.; Grupen, C.; Haungs, A.; Heck, D.; Hörandel, J. R.; Horneffer, A.; Huber, D.; Huege, T.; Isar, P. G.; Kampert, K.-H.; Kang, D.; Krömer, O.; Kuijpers, J.; Link, K.; Łuczak, P.; Ludwig, M.; Mathes, H. J.; Melissas, M.; Morello, C.; Oehlschläger, J.; Palmieri, N.; Pierog, T.; Rautenberg, J.; Rebel, H.; Roth, M.; Rühle, C.; Saftoiu, A.; Schieler, H.; Schmidt, A.; Schoo, S.; Sima, O.; Toma, G.; Trinchero, G. C.; Weindl, A.; Wochele, J.; Zabierowski, J.; Zensus, J. A.

2015-08-01

LOPES was a digital antenna array operating for approximately 10 years until spring 2013 at the Karlsruhe Institute of Technology (KIT). Triggered by the co-located KASCADE-Grande air-shower experiment, it measured the radio signal of around 1000 cosmic-ray air showers with energies E ≳ 1017 eV in an effective band of 43 - 74 MHz. Using the interferometric technique of cross-correlation beamforming, LOPES could reconstruct the shower direction with an accuracy < 0.7°, the shower energy with a precision < 20%, and the atmospheric depth of the shower maximum, Xmax, with a precision < 95g/cm2. In particular the reconstruction of the shower maximum suffers from significant measurement uncertainties due to the radio-loud environment of the site. This article summarizes our latest results on the reconstruction of the shower maximum, using two independent methods: the steepness of the hyperbolic radio wavefront and the slope of the lateral distribution of the radio amplitude. Moreover, we show vectorial measurements of the electric field with the tripole antennas of the latest LOPES setup. Finally, we discuss open questions as well as the potential impact of the lessons learned at LOPES for future antenna arrays.

The European Ruminants during the “Microbunodon Event” (MP28, Latest Oligocene): Impact of Climate Changes and Faunal Event on the Ruminant Evolution

PubMed Central

Mennecart, Bastien

2015-01-01

The Earth already experienced numerous episodes of global warming and cooling. One of the latest impressive events of temperature rising was the Late Oligocene Warming that occurred around 25 Mya. An increase of the marine temperature of 2 to 4°C has been observed in a short time interval. In Europe, this major climatic event can be correlated to the continental faunal turnover “Microbunodon Event”. This event is marked by a huge faunal turnover (40% of the ungulate fauna during the first 500k years) and environmental changes. Drier conditions associated to the appearance of the seasonality lead to new environmental conditions dominated by wooded savannahs. This is correlated to a major arrival of Asiatic immigrants. Moreover, from a homogenous fauna during the main part of the Oligocene, local climatic variations between the European Western coast and the more central Europe could have provided faunal regionalism during the latest Oligocene and earliest Miocene. Considering the ruminants, this event is the major ever known for this group in Europe. A total renewal at the family level occurred. Thanks to a precise stratigraphic succession, major evolutionary elements are highlighted. Typical Oligocene species, mainly Tragulina, were adapted to wooded environments and were leaves/fruits eaters. They disappeared at the end of MP27 or the early MP28. This corresponds to the appearance of the Asiatic immigrants. The Tragulina (Lophiomerycidae, Bachitheriidae) and stem Pecora gave way to more derived stem and maybe crown Pecora (e.g. “Amphitragulus”, Babameryx, Dremotherium). These newcomers were adapted to more open environments and mixed feeding. The disappearance of the Tragulina is probably linked to environmental and vegetation changes, and competition. They give way to more derived ruminants having a more efficient metabolism in drier conditions and a better assimilation of less energetic food. PMID:25692298

Small But Increasingly Mighty: Latest Advances in AAV Vector Research, Design, and Evolution.

PubMed

Grimm, Dirk; Büning, Hildegard

2017-11-01

Recombinant gene delivery vectors derived from naturally occurring or genetically engineered adeno-associated viruses (AAV) have taken center stage in human gene therapy, fueled by rapidly accumulating and highly encouraging clinical data. Nonetheless, it has also become evident that the current generation of AAV vectors will require improvements in transduction potency, antibody evasion, and cell specificity in order to realize their full potential and to widen applicability in larger patient cohorts. Fortunately, in the recent past, the field has seen a flurry of exciting new developments that enhance our understanding of AAV vector biology, including virus-host interactions, and/or that expand our arsenal of technologies for AAV capsid design and evolution. This review highlights a collection of latest advances in these areas, which, in the authors' opinion, hold particular promise to propel the AAV vector field forward in the near future, especially when applied in combination. These include fundamental novel insights into the AAV life cycle, from an unexpected role of autophagy and interactions with other viruses to the (re-)discovery of a universal AAV receptor and the function of AAV-AAP for capsid assembly. Concurrently, recent successes in the rational design of next-generation synthetic AAV capsids are pointed out, exemplified by the structure-guided derivation of AAV mutants displaying robust in vivo immune evasion. Finally, a variety of new and innovative strategies for high-throughput generation and screening of AAV capsid libraries are briefly reviewed, including Cre recombinase-based selection, ancestral AAV capsid reconstruction, and DNA barcoding of AAV genomes. All of these examples showcase the present momentum in the AAV field and, together with work by many other academic or industrial entities, raise substantial optimism that the remaining hurdles for human gene therapy with AAV vectors will (soon) be overcome.

Laboratory spectroscopy of Mars Analogue materials and latest field results from Iceland and Eifel

NASA Astrophysics Data System (ADS)

Offringa, Marloes; Foing, Bernard H.

2016-07-01

We have established a collection of samples, and measured them in the laboratory towards a spectrometric database that could be used as a reference for future orbital or in situ measurements. We are using systematically for all samples UV-VIS and NIR reflectance spectrometers, and sporadically a Fourier Transform Infrared (FTIR) spectrometer, an X-Ray Fluorescence (XRF) spectrometer and a Raman laser spectrometer on control samples. We also used a documented set of Moon-Mars relevant minerals curated at VU Amsterdam, as well as samples retrieved from Mars analogue campaigns in Utah (Foing et al., 2011, 2016), Iceland (Mid-Atlantic ridge spreading and magma-ice interaction), La Réunion hot spot volcano and Eifel volcanic region (mixed hotspot and melt-ascent through crust fractures) from recent campaigns in 2015 and 2016.. We discuss samples spectral diagnostics of volcanic processes and hydrous alterations that can inform recent or upcoming measurements from Mars orbit or in situ rovers. Acknowledgements: we thank Dominic Doyle for ESTEC optical lab support, Euan Monaghan (Leiden U) for FTIR measurement support, Wim van Westrenen for access to VU samples, Oscar Kamps (Utrecht U), Aidan Cowley (EAC) and Matthias Sperl (DLR) for support discussions

Ground-based Efforts to Support a Space-based Experiment: the Latest LADEE Results (Abstract)

NASA Astrophysics Data System (ADS)

Cudnik, B.; Rahman, M.

2014-12-01

(Abstract only) The much anticipated launch of NASA’s Lunar Atmosphere and Dust Environment Explorer happened flawlessly last October and the satellite has been doing science (and sending a few images) since late Novermber. [The LADEE mission ended with the crash-landing of the spacecraft on the lunar far side on April 17, 2014, capping a successful 140-day mission.] We also have launched our campaign to document lunar meteroid impact flashes from the ground to supply ground truth to inform of any changes in dust concentration encountered by the spacecraft in orbit around the moon. To date I have received six reports of impact flashes or flash candidates from the group I am coordinating; other groups around the world may have more to add when all is said and done. In addition, plans are underway to prepare a program at Prairie View A&M University to involve our physics majors in lunar meteoroid, asteroid occultation, and other astronomical work through our Center for Astronomical Sciences and Technology. This facility will be a control center to not only involve physics majors, but also to include pre-service teachers and members of the outside community to promote pro-am collaborations.

Comparison between simulations and lab results on the ASSIST test-bench

NASA Astrophysics Data System (ADS)

Le Louarn, Miska; Madec, Pierre-Yves; Kolb, Johann; Paufique, Jerome; Oberti, Sylvain; La Penna, Paolo; Arsenault, Robin

2016-07-01

We present the latest comparison results between laboratory tests carried out on the ASSIST test bench and Octopus end-to end simulations. We simulated, as closely to the lab conditions as possible, the different AOF modes (Maintenance and commissioning mode (SCAO), GRAAL (GLAO in the near IR), Galacsi Wide Field mode (GLAO in the visible) and Galacsi narrow field mode (LTAO in the visible)). We then compared the simulation results to the ones obtained on the lab bench. Several aspects were investigated, like number of corrected modes, turbulence wind speeds, LGS photon flux etc. The agreement between simulations and lab is remarkably good for all investigated parameters, giving great confidence in both simulation tool and performance of the AO system in the lab.

The relevance of the IUE results on young stars for Earth's paleoatmosphere

NASA Technical Reports Server (NTRS)

Canuto, V. M.; Levine, J. S.; Augustsson, T. R.; Imhoff, C. L.; Giampap, M. S.

1982-01-01

Using the latest IUE results for seven T Tauri stars, which are believed to represent the young Sun and a detailed photochemical chemical model of the paleoatmosphere, the vertical distribution of Oxygen and Ozone in the early atmosphere was calculated. The calculations indicate that the surface Oxygen mixing ratio is as much as six orders of magnitude larger than previously estimated, but appears low enough for the formation of amino acids via the Urey-Miller type of experiments. It is believed that the quantification of the oxygen level in the Earth's paleoatmosphere presented can reconcile the demands of both biological and geological considerations.

Planktic foraminiferal response to the Latest Danian Event in the Pacific Ocean (ODP Site 1210)

NASA Astrophysics Data System (ADS)

Jehle, Sofie; Bornemann, André; Deprez, Arne; Speijer, Robert

2015-04-01

suggest that this taxon benefits from a shallower thermocline and, thus, increased stratification. After the event, photosymbiotic activity in surface dwellers like Morozovella might have been boosted due to less competitive pressure. Minor dissolution according to planktic foraminiferal fragmentation, P/B-ratios and coarse fraction is considered to be present during the LDE. This observation is consistent with a decrease in the total CaCO3 record, which drops from ~95% to 85%, while planktic foraminifera suffer a strong decrease in abundance from ~20,000 to ~1,000 speciemn per gram during the event. Results from Non-metric Multidimentional Scaling suggest distinct faunal changes between before, during and after the LDE. Prominent changes are especially the disappearance of Praemurica spp. shortly before or with the onset of the event, whereas Igorina albeari increases from 'few' to 'abundant' within the first Fe LDE peak. Morozovella angulata follows a slow but constant rise, while M. praeangulata has the opposite trend. Comparable obervations were done on genus level at the Tethys Ocean, Tunisia (Guasti et al., 2006). References Bornemann, A., Schulte, P., Sprong, J., Steurbaut, E., Youssef, M., Speijer, R.P., 2009. Latest Danian carbon isotope anomaly and associated environmental change in the southern Tethys (Nile Basin, Egypt). Journal of the Geological Society 166, 1135-1142. Guasti, E., Speijer, R.P., Brinkhuis, H., Smit, J., Steurbaut, E., 2006. Paleoenvironmental change at the Danian-Selandian transition in Tunisia: Foraminifera, organic-walled dinoflagellate cyst and calcareous nannofossil records. Marine Micropaleontology 59, 210-229. Westerhold, T., Röhl, U., Raffi, I., Fornaciari, E., Monechi, S., Reale, V., Bowles, J., Evans, H.F., 2008. Astronomical calibration of the Paleocene time. Palaeogegr. Palaeoclimatol. Palaeoecol. 257, 377-403. Westerhold, T., Röhl, U., Donner, B., McCarren, H.K., Zachos, J.C., 2011. A complete high-resolution Paleocene benthic

Neutrino astronomy at the South Pole: Latest results from the IceCube neutrino observatory and its future development

NASA Astrophysics Data System (ADS)

Toscano, S.; IceCube Collaboration

2017-12-01

The IceCube Neutrino Observatory is a cubic-kilometer neutrino telescope located at the geographic South Pole. Buried deep under the Antarctic ice sheet, an array of 5160 Digital Optical Modules (DOMs) is used to capture the Cherenkov light emitted by relativistic particles generated from neutrino interactions. The main goal of IceCube is the detection of astrophysical neutrinos. In 2013 the IceCube neutrino telescope discovered a high-energy diffuse flux of neutrino events with energy ranging from tens of TeV up to few PeV of cosmic origin. Meanwhile, different analyses confirm the discovery and search for possible correlations with astrophysical sources. However, the source of these neutrinos remains a mystery, since no counterparts have been identified yet. In this contribution we give an overview of the detection principles of IceCube, the most recent results, and the plans for a next-generation neutrino detector, dubbed IceCube-Gen2.

Results from the NEXT Protogypes

DOE PAGES

Oliveira, C A.B.

2013-10-04

NEXT-100 is an electroluminescent high pressure Time Projection Chamber currently under construction. It will search for the neutrino-less double beta decay in 136Xe at the Canfranc Underground Laboratory. NEXT-100 aims to achieve nearly intrinsic energy resolution and to highly suppress background events by taking advantage of the unique properties of xenon in the gaseous phase as the detection medium. In order to prove the principle of operation and to study which are the best operational conditions, two prototypes were constructed: NEXT-DEMO and NEXT-DBDM. In this study we present the latest results from both prototypes. We report the improvement in termsmore » of light collection (~ 3x) achieved by coating the walls of NEXT-DEMO with tetraphenyl butadiene (TPB), the outstanding energy resolution of 1% (Full Width Half Maximum) from NEXT-DBDM as well as the tracking capabilities of this prototype (2.1 mm RMS error for point-like depositions) achieved by using a square array of 8 x 8 SiPMs.« less

First Results From The Ultimate Spitzer Phase Curve Survey

NASA Astrophysics Data System (ADS)

Stevenson, Kevin B.; Bean, Jacob; Deming, Drake; Desert, Jean-Michel; Fortney, Jonathan J.; Kataria, Tiffany; Kempton, Eliza; Lewis, Nikole; Line, Michael R.; Morley, Caroline; Rauscher, Emily; Showman, Adam P.

2017-10-01

Exoplanet phase curves provide a wealth of information about exoplanet atmospheres, including longitudinal constraints on atmospheric composition, thermal structure, and energy transport, that continue to open new doors of scientific inquiry and propel future investigations. The measured heat redistribution efficiency (or ability to transport energy from a planet's highly-irradiated dayside to its eternally-dark nightside) shows considerable variation between exoplanets. Theoretical models predict a correlation between heat redistribution efficiency and planet temperature; however, the latest results are inconsistent with current predictions. We will present first results from a 660-hour Spitzer phase curve survey program that is targeting six short-period extrasolar planets. We will compare the measured heat redistribution efficiencies with planet temperature and rotation rate, examine trends in the phase curve peak offset, and discuss cloud coverage constraints. We will conclude with how to move forward with phase curve observations in the era of JWST.

The Use of GOCE/GRACE Information in the Latest NGS xGeoid15 Model for the USA

NASA Astrophysics Data System (ADS)

Holmes, S. A.; Li, X.; Youngman, M.

2015-12-01

The U.S. National Geodetic Survey [NGS], through its Gravity for the Redefinition of the American Vertical Datum [GRAV-D] program, is flying airborne gravity surveys over the USA and its territories. By 2022, NGS intends that all orthometric heights in the USA will be determined in the field using a reliable national gravimetric geoid model to transform from geodetic heights obtained from GPS. Towards this end, all available airborne data has been incorporated into a new NGS experimental geoid model - xGEOID15. The xGEOID15 model is the second in a series of annual experimental geoid models that incorporates NGS GRAV-D airborne data. This series provides a useful benchmark for assessing and improving current techniques, to ultimately compute a geoid model that can support a national physical height system by 2022. Here, we focus on the combination of the latest GOCE/GRACE models with the terrestrial gravimetry (land/airborne) that was applied for xGeoid15. Comparisons against existing combination gravitational solutions, such as EGM2008 and EIGEN6C4, as well as recent geoid models, such as xGeoid14 and CGG2013, are interesting for what they reveal about the respective use of the GOCE/GRACE satgrav information.

Hydrothermal activity and its paleoecological implications in the latest Miocene to Middle Pleistocene lacustrine environments of the Baza Basin (Betic Cordillera, SE Spain)

NASA Astrophysics Data System (ADS)

García-Aguilar, José Manuel; Guerra-Merchán, Antonio; Serrano, Francisco; Palmqvist, Paul; Flores-Moya, Antonio; Martínez-Navarro, Bienvenido

2014-07-01

The continental sedimentary record of the Baza Basin (Guadix-Baza Depression, Betic Cordillera, SE Spain) shows six sedimentary units of lacustrine origin deposited from the latest Miocene to the Middle Pleistocene. Depending on the interval considered, the lacustrine deposits are mainly composed of marls, carbonates or gypsiferous evaporites, showing lithological, mineralogical and geochemical features (i.e., magnesium, strontium and sulfur contents, celestine deposits and travertine growths) that are evidence of intense, tectonically-induced hydrothermal activity. According to the high concentrations of strontium and sulfur as well as the abundance of travertines and magnesium clays, the supply of hot waters was greater during the Zanclean, the Gelasian and the Calabrian, as a result of tectonic activity. Hydrothermal activity has continued until the present time and is responsible of the hot springs that are nowadays active in the Guadix-Baza Depression. The paleoenvironmental consequences of these sublacustrine hot springs were that during some intervals the lakes maintained a relatively permanent water table, not subject to periodic desiccations in the dry season, and warmer temperatures throughout the year. This resulted in a high level of organic productivity, especially for the Calabrian, which allowed the development of a rich and well diversified mammalian community, similar to those of modern African savannas with tree patches. In this mild environment, the permanent water sheet favored the presence of drought intolerant megaherbivores such as the giant extinct hippo Hippopotamus antiquus. The high standing crop biomass of ungulates resulted in the availability of abundant carcasses for scavengers such as hyenas and hominins, which explains the very high densities of skeletal remains preserved in the sediments distributed along the lake surroundings.

Ñuagapua (Chaco, Bolivia): Evidence for the latest occurrence of megafauna in association with human remains in South America

NASA Astrophysics Data System (ADS)

Coltorti, Mauro; Della Fazia, Jacopo; Paredes Rios, Freddy; Tito, Giuseppe

2012-02-01

Quebrada (stream) Ñuagapua, which is located in the Bolivian Chaco in the Andean foothill generates an alluvial fan many kilometres in length. Three major lithostratigraphic units characterise the sedimentary sequence in this region. The lower and upper parts are formed from predominantly sandy sediments that demonstrate rapid growth of the alluvial fan, associated with an intense erosion of barren slopes. The intermediate unit consists of forest soil that seals deep channels containing bones together with a forest association. The remains of a wooden plank, dated 140 yr BP, were found at the top of this soil, which laterally contains charcoals, ash layers and large charred trunks, sometimes in growth positions. Roots localised in this layer also sustain a number of very large still living trees. These findings are evidence of a recent phase of alluvial fan sedimentation resulting from slope erosion activated by forest clearing. The Chaco has been intensively settled for agricultural and pastoral purposes since the 18th century. The lower unit contains a hearth, scattered burnt bones, flint flakes and ceramic artefacts. Radiometric dating indicates a middle Holocene human occupation, between ca. 7.79 and 6.65 ka cal yr BP. We suggest that the sedimentary unit is associated with intense soil erosion processes triggered by early Neolithic deforestation. A sandy layer of the lower unit, slightly above the archaeological remains, contains transported bones of megafaunal elements that apparently represent the South American latest occurrence of some extinct taxa. The mammal association is highly heterogeneous, containing species living in aquatic, forest, prairie and savannah environments from a very specific layer that represents the almost simultaneous burial of animals killed slightly up-valley. This anomalous association is probably the result of human impact as opening the forest favoured the introduction of open environment fauna that had previously survived on

Latest research results on the effects of nanomaterials on humans and the environment: DaNa - Knowledge Base Nanomaterials

NASA Astrophysics Data System (ADS)

Marquardt, C.; Kühnel, D.; Richter, V.; Krug, H. F.; Mathes, B.; Steinbach, C.; Nau, K.

2013-04-01

Nanotechnology is considered one of the key technologies of the 21st century. The success of this fascinating technology is based on its versatility. It will bring about fundamental changes of basic research as well as of many sectors of industry and also of daily life from electronics to the health care system. However, consumers often miss reliable and understandable information on nanomaterials and all aspects of this versatile technology. A huge body of data on the potential hazards of nanoobjects towards human and environmental health already exists, but is either not easily accessible for a broad audience or presented unprocessable for nonexperts. But risk communication is an essential and thus integral component of risk management. For that purpose, the DaNa-Project aims at filling this gap by collecting and evaluating scientific results in an interdisciplinary approach with scientists from different research areas, such as human and environmental toxicology, biology, physics, chemistry, and sociology. Research findings from the field of human and environmental nanotoxicology are being prepared and presented together with material properties and possible applications for interested laymen and stakeholders. For the evaluation of literature a "Literature Criteria Checklist" has been developed as well as a Standard Operation Procedure template (SOP) based on careful scientific practice.

HgCdTe Detectors for Space and Science Imaging: General Issues and Latest Achievements

NASA Astrophysics Data System (ADS)

Gravrand, O.; Rothman, J.; Cervera, C.; Baier, N.; Lobre, C.; Zanatta, J. P.; Boulade, O.; Moreau, V.; Fieque, B.

2016-09-01

HgCdTe (MCT) is a very versatile material system for infrared (IR) detection, suitable for high performance detection in a wide range of applications and spectral ranges. Indeed, the ability to tailor the cutoff frequency as close as possible to the needs makes it a perfect candidate for high performance detection. Moreover, the high quality material available today, grown either by molecular beam epitaxy or liquid phase epitaxy, allows for very low dark currents at low temperatures, suitable for low flux detection applications such as science imaging. MCT has also demonstrated robustness to the aggressive environment of space and faces, therefore, a large demand for space applications. A satellite may stare at the earth, in which case detection usually involves a lot of photons, called a high flux scenario. Alternatively, a satellite may stare at outer space for science purposes, in which case the detected photon number is very low, leading to low flux scenarios. This latter case induces very strong constraints onto the detector: low dark current, low noise, (very) large focal plane arrays. The classical structure used to fulfill those requirements are usually p/ n MCT photodiodes. This type of structure has been deeply investigated in our laboratory for different spectral bands, in collaboration with the CEA Astrophysics lab. However, another alternative may also be investigated with low excess noise: MCT n/ p avalanche photodiodes (APD). This paper reviews the latest achievements obtained on this matter at DEFIR (LETI and Sofradir common laboratory) from the short wave infrared (SWIR) band detection for classical astronomical needs, to long wave infrared (LWIR) band for exoplanet transit spectroscopy, up to very long wave infrared (VLWIR) bands. The different available diode architectures ( n/ p VHg or p/ n, or even APDs) are reviewed, including different available ROIC architectures for low flux detection.

Study the gradient characteristics of the ionosphere at equatorial latitude during the latest cycle of solar activity

NASA Astrophysics Data System (ADS)

Nguyen Thai, Chinh; Temitope Seun, Oluwadare; Le Thi, Nhung; Schuh, Harald

2017-04-01

The sun has its own seasons with an average duration of about 11 years. In this time, the sun enters a period of increased activity called the solar maximum and a period of decreased activity called the solar minimum. Cycles span from one minimum to the next. The current solar cycle is 24, which began on January 4, 2008 and is expected to be ended in 2019. During this period, the ionosphere changes its thickness and its characteristics as well. The change is most complicated and unpredictable at the equatorial latitudes in a band around 150 northward and 150 southward from the equator. Thailand is located in these regions is known as one of the countries most affected by the ionosphere change. Ionospheric information such as the vertical total electron content (VTEC) and scintillation indices can be extracted from the measurements of GNSS dual-frequency receivers. In this study, a Matlab tool is programmed to calculate some ionosphere parameters from the normal RINEX observation file including VTEC value, amplitude scintillation S4 index and others. The value of VTEC at one IGS station in Thailand (13.740N, 100.530E) is computed for almost one full solar cycle, that is 8 years, from 2009 to 2016. From these results, we are able to derive the rules of TEC variation over time and its dependence on solar activity in the equatorial regions. The change of VTEC is estimated in diurnal, seasonal and annual variation for the latest solar cycle. The solar cycle can be represented in several ways, in this paper we use the sunspot number and the F10.7 cm radio flux to describe the solar activity. The correlation coefficients between these solar indices and the monthly maximum of VTEC value are around 0.87, this indicates a high dependence of the ionosphere on solar activity. Besides, a scintillation map derived from GNSS data is displayed to indicate the intensity of scintillation activity.

Recent Borexino results and prospects for the near future

NASA Astrophysics Data System (ADS)

D'Angelo, D.; Agostini, M.; Altenmüller, K.; Appel, S.; Bellini, G.; Benziger, J.; Bick, D.; Bonfini, G.; Bravo, D.; Caccianiga, B.; Calaprice, F.; Caminata, A.; Cavalcante, P.; Chepurnov, A.; Davini, S.; Derbin, A.; Di Noto, L.; Drachnev, I.; Etenko, A.; Fomenko, K.; Franco, D.; Gabriele, F.; Galbiati, C.; Ghiano, C.; Giammarchi, M.; Goeger-Neff, M.; Goretti, A.; Gromov, M.; Hagner, C.; Hungerford, E.; Ianni, Aldo; Ianni, Andrea; Jedrzejczak, K.; Kaiser, M.; Kobychev, V.; Korablev, D.; Korga, G.; Kryn, D.; Laubenstein, M.; Lehnert, B.; Litvinovich, E.; Lombardi, F.; Lombardi, P.; Ludhova, L.; Lukyanchenko, G.; Machulin, I.; Manecki, S.; Maneschg, W.; Marcocci, S.; Meroni, E.; Meyer, M.; Miramonti, L.; Misiaszek, M.; Montuschi, M.; Mosteiro, P.; Muratova, V.; Neumair, B.; Oberauer, L.; Obolensky, M.; Ortica, F.; Pallavicini, M.; Papp, L.; Perasso, L.; Pocar, A.; Ranucci, G.; Razeto, A.; Re, A.; Romani, A.; Roncin, R.; Rossi, N.; Schönert, S.; Semenov, D.; Simgen, H.; Skorokhvatov, M.; Smirnov, O.; Sotnikov, A.; Sukhotin, S.; Suvorov, Y.; Tartaglia, R.; Testera, G.; Thurn, J.; Toropova, M.; Unzhakov, E.; Vishneva, A.; Vogelaar, R. B.; von Feilitzsch, F.; Wang, H.; Weinz, S.; Winter, J.; Wojcik, M.; Wurm, M.; Yokley, Z.; Zaimidoroga, O.; Zavatarelli, S.; Zuber, K.; Zuzel, G.

2016-11-01

The Borexino experiment located in the Gran Sasso National Laboratory, is an organic liquid scintillator detector conceived for the real time spectroscopy of low energy solar neutrinos. The phase-I of the data taking campaign (2007 - 2010) has allowed the first independent measurements of 7Be and pep solar neutrino fluxes as well as the first measurement of anti-neutrinos from the Earth. After a purification of the scintillator, Borexino is now in phase-II since 2011. Thanks to the unprecedented background levels, we have performed the first flux measurement of neutrinos from the fundamental pp reaction which powers the Sun. We review this breakthrough result and other recent results, including the latest review of our terrestrial neutrino analysis. We also discuss the upcoming measurements on middle energy solar neutrino spectral components (pep, CNO) and the new project SOX devoted to the study of sterile neutrinos via the use of a neutrino source placed in close proximity of the detector's active material.

Results on top-quark physics and top-quark-like signatures by CMS

NASA Astrophysics Data System (ADS)

Chabert, Eric; CMS Collaboration

2017-07-01

This report reviews the results obtained by the CMS Collaboration on top quark physics, focusing on the latest ones based on p-p collisions provided by the LHC at \\sqrt{s}=13{{TeV}} during Run II. It covers measurements of single-top, top quark pairs and associated productions as well as measurements of top quark properties. Finally several beyond the standard model searches involving top quark in the final states are presented, such as searches for supersymmetry in the third generation, heavy resonances decaying into a top quark pair, or dark matter produced in association to a single-top or a top quark pair.

Fasting for weight loss: an effective strategy or latest dieting trend?

PubMed

Johnstone, A

2015-05-01

With the increasing obesity epidemic comes the search for effective dietary approaches for calorie restriction and weight loss. Here I examine whether fasting is the latest 'fad diet' as portrayed in popular media and discuss whether it is a safe and effective approach or whether it is an idiosyncratic diet trend that promotes short-term weight loss, with no concern for long-term weight maintenance. Fasting has long been used under historical and experimental conditions and has recently been popularised by 'intermittent fasting' or 'modified fasting' regimes, in which a very low-calorie allowance is allowed, on alternate days (ADF) or 2 days a week (5:2 diet), where 'normal' eating is resumed on non-diet days. It is a simple concept, which makes it easy to follow with no difficult calorie counting every other day. This approach does seem to promote weight loss, but is linked to hunger, which can be a limiting factor for maintaining food restriction. The potential health benefits of fasting can be related to both the acute food restriction and chronic influence of weight loss; the long-term effect of chronic food restriction in humans is not yet clear, but may be a potentially interesting future dietary strategy for longevity, particularly given the overweight epidemic. One approach does not fit all in the quest to achieve body weight control, but this could be a dietary strategy for consideration. With the obesity epidemic comes the search for dietary strategies to (i) prevent weight gain, (ii) promote weight loss and (iii) prevent weight regain. With over half of the population of the United Kingdom and other developed countries being collectively overweight or obese, there is considerable pressure to achieve these goals, from both a public health and a clinical perspective. Certainly not one dietary approach will solve these complex problems. Although there is some long-term success with gastric surgical options for morbid obesity, there is still a requirement

Large co-axial pulse tube preliminary results

NASA Astrophysics Data System (ADS)

Emery, N.; Caughley, A.; Meier, J.; Nation, M.; Tanchon, J.; Trollier, T.; Ravex, A.

2014-01-01

We report that Callaghan Innovation, formally known as Industrial Research Ltd (IRL), has designed and built its largest of three high frequency single-stage co-axial pulse tubes, closely coupled to a metal diaphragm pressure wave generator (PWG). The previous pulse tube achieved 110 W of cooling power @ 77 K, with an electrical input power of 3.1 kW from a 90 cc swept volume PWG. The pulse tubes have all been tuned to operate at 50 Hz, with a mean helium working pressure of 2.5 MPa. Sage pulse tube simulation software was used to model the latest pulse tube and predicted 280 W of cooling power @ 77 K. The nominal 250 W cryocooler was designed to be an intermediate step to up-scale pulse tube technology for our 1000 cc swept-volume PWG, to provide liquefaction of gases and cooling for HTS applications. Details of the modeling, design, development and preliminary experimental results are discussed.

Latest achievements in PET techniques

NASA Astrophysics Data System (ADS)

Del Guerra, Alberto; Belcari, Nicola; Motta, Alfonso; Di Domenico, Giovanni; Sabba, Nicola; Zavattini, Guido

2003-11-01

Positron emission tomography (PET) has moved from a distinguished research tool in physiology, cardiology and neurology to become a major tool for clinical investigation in oncology, in cardiac applications and in neurological disorders. Much of the PET accomplishments is due to the remarkable improvements in the last 10 years both in hardware and software aspects. Nowadays a similar effort is made by many research groups towards the construction of dedicated PET apparatus in new emerging fields such as molecular medicine, gene therapy, breast cancer imaging and combined modalities. This paper reports on some recent results we have obtained in small animal imaging and positron emission mammography, based on the use of advanced technology in the field of scintillators and photodetectors, such as Position-Sensitive Detectors coupled to crystal matrices, combined use of scintillating fibers and Hybrid-Photo-Diodes readout, and Hamamatsu flat panels. New ideas and future developments are discussed.

Overview of MAGIC results

NASA Astrophysics Data System (ADS)

Rico, Javier; MAGIC Collaboration

2016-04-01

MAGIC is a system of two 17-m diameter Cherenkov telescopes, located at the Observatorio del Roque de los Muchachos, in the Canary island La Palma (Spain). MAGIC performs astronomical observations of gamma-ray sources in the energy range between 50 GeV and 10 TeV. The first MAGIC telescope has been operating since 2004, and in 2009 the system was completed with the second one. During 2011 and 2012 the electronics for the readout system were fully upgraded, and the camera of the first telescope replaced. After that, no major hardware interventions are foreseen in the next years, and the experiment has undertaken a final period of steady astronomical observations. MAGIC studies particle acceleration in the most violent cosmic environments, such as active galactic nuclei, gamma-ray bursts, pulsars, supernova remnants or binary systems. In addition, it addresses some fundamental questions of Physics, such as the origin of Galactic cosmic rays and the nature of dark matter. Moreover, by observing the gamma-ray emission from sources at cosmological distances, we measure the intensity and evolution of the extragalactic background radiation, and perform tests of Lorentz Invariance. In this paper I present the status and some of the latest results of the MAGIC gamma-ray telescopes.

Double differential neutron spectra generated by the interaction of a 12 MeV/nucleon 36S beam on a thick natCu target

NASA Astrophysics Data System (ADS)

Trinh, N. D.; Fadil, M.; Lewitowicz, M.; Ledoux, X.; Laurent, B.; Thomas, J.-C.; Clerc, T.; Desmezières, V.; Dupuis, M.; Madeline, A.; Dessay, E.; Grinyer, G. F.; Grinyer, J.; Menard, N.; Porée, F.; Achouri, L.; Delaunay, F.; Parlog, M.

2018-07-01

Double differential neutron spectra (energy, angle) originating from a thick natCu target bombarded by a 12 MeV/nucleon 36S16+ beam were measured by the activation method and the Time-of-flight technique at the Grand Accélérateur National d'Ions Lourds (GANIL). A neutron spectrum unfolding algorithm combining the SAND-II iterative method and Monte-Carlo techniques was developed for the analysis of the activation results that cover a wide range of neutron energies. It was implemented into a graphical user interface program, called GanUnfold. The experimental neutron spectra are compared to Monte-Carlo simulations performed using the PHITS and FLUKA codes.

Use of a latest-generation vascular plug for peripheral vascular embolization with use of a diagnostic catheter: preliminary clinical experience.

PubMed

Mordasini, Pasquale; Szucs-Farkas, Zsolt; Do, Do-Dai; Gralla, Jan; Kettenbach, Joachim; Hoppe, Hanno

2010-08-01

The latest-generation Amplatzer vascular plug (AVP), the AVP 4, is designed for embolization of smaller vessels without a sheath or guiding catheter. This study evaluated the AVP 4 in peripheral vascular embolization. Embolization with the AVP 4 was attempted in 13 patients (11 men) for trauma (n = 7) and other indications (n = 6). Technical success rate, vascular bed, size of catheter, and number and size of AVP 4 devices were recorded. Embolization with the AVP 4 was successful in 10 of 13 patients (77%). In trauma patients (n = 7), embolization of the splenic artery (n = 4), lumbar artery (n = 2), and superior gluteal artery (n = 1) was performed. In other patients, preoperative embolization of the right portal vein (n = 1), a gastric varix after transjugular intrahepatic portosystemic shunt creation (n = 1), an aneurysm of the internal iliac artery (n = 1), and inferior mesenteric artery (IMA) embolization before aneurysm repair (n = 2) was performed. Sizes of the AVP 4 were 4 mm (n = 6), 6 mm (n = 5), and 8 mm (n = 1). In all patients, 4- and 5-F catheters with a 0.038-inch minimum inner lumen were used. In one patient, IMA embolization was attempted via a femoral approach but was unsuccessful as a result of repeated catheter tip dislocation because of acute angle; coils were used instead. Peripheral embolization with the AVP 4 was successful in the majority of patients. Future comparative study is necessary to evaluate this device's benefits over other embolization materials such as earlier-generation AVPs or microcoils. Copyright (c) 2010 SIR. Published by Elsevier Inc. All rights reserved.

The latest views of Venus as observed by the Japanese Orbiter "Akatsuki"

NASA Astrophysics Data System (ADS)

Satoh, Takehiko; Akatsuki Project Team

2016-10-01

visible wavelengths), as well as the ultra-stable oscillator for radio-occultation measurements.At the lecture, the latest views of Venus as acquired with these instruments on Akatsuki will be presented.

Large variations in the hydrology for the Paratethys-Mediterranean system during latest Miocene - insights from the hydrogen isotopes on biomarkers

NASA Astrophysics Data System (ADS)

Vasiliev, I.; Reichart, G. J.

2016-12-01

Paratethys - Mediterranean domain, occupying southern Eurasia and northern Africa, was a sea system characterized by recurrently restricted connections to the Open Ocean. To determine the nature of changes in the hydrological budget of the Paratethys - Mediterranean domain occurring during the latest Miocene we use compound-specific hydrogen isotope ratios on terrestrial and aquatic biomarkers extracted at four different locations: 1) the land based sedimentary succession located on Taman Peninsula in Russia, 2) the deep sea succession recovered in 1975 from the Black Sea, 3) the succession of Northern Apennines and Sicily from Italy and 4) the sedimentary infill of the Carpathians Foredeep from the Dacian Basin of Romania. The hydrogen isotopic compositions of n-alkanes (produced predominantly by higher plants) as well as alkenones (produced by haptophyte algae) indicate large environmental changes in the Paratethys-Mediterranean. The hydrogen isotopes of alkenones, showing an enrichment of more than 80‰ at the end of the Miocene, imply a major shift in basin hydrology, possibly resulting in severely increased salinity. These changes in hydrogen isotopic composition of the alkenones concur both with sharp shifts in reconstructed sea surface temperatures and mean annual temperatures. An interval with negative water budget was identified in all sections, most likely caused by enhanced evaporation during the Messinian salinity crisis (5.97 - 5.33 Ma). Additionally, the 60‰ amplitude of changes measured on long chain n-alkanes, produced predominantly by higher plants, can be principally explained by significant changes in the hydrogen isotopic composition of the precipitation reaching the Paratethys-Mediterranean system during the Messinian salinity crisis. These cumulated hydrogen isotopic compositions results indicate that the hydrological regime in Paratethys - Mediterranean domain has significantly varied, with heaviest δD values being recorded from a time

Stratigraphic response across a structurally dynamic shelf: The latest guadalupian composite sequence at Walnut Canyon, New Mexico, U.S.A

USGS Publications Warehouse

Rush, J.; Kerans, C.

2010-01-01

was subsequently reactivated during the latest Guadalupian lowstand and was subaerially filled by siliciclastics and polymict breccia derived from the platform top. Results from Walnut Canyon indicate that shelf crest aggradation dominantly controlled the shelf-crest to outer-shelf profile, although this was temporarily modified by brittle failure and down-to-the-basin tilting, and mass wasting. Copyright ?? 2010, SEPM (Society for Sedimentary Geology).

Environmental benefits and concerns on safety: communicating latest results on nanotechnology safety research-the project DaNa2.0.

PubMed

Kühnel, D; Marquardt, C; Nau, K; Krug, H F; Paul, F; Steinbach, C

2017-04-01

The use of nanotechnology and advanced materials promises to revolutionise many areas of technology and improve our daily life. In that respect, many positive effects on the environment are expected, either directly, by developing new technologies for remediation, filtering techniques or energy generation, or indirectly, by e.g. saving resources due to lower consumption of raw materials, or lower energy and fuel consumption due to reduced weight of vehicles. However, such beneficial effects of new technologies are often confronted by concerns regarding the safety of novel substances or materials. During the past 10 years, great effort has been put into research on potential hazards of nanomaterials towards environmental organisms. As the methodology for reliable assessment of nanomaterials was immature, many studies reporting contradictory results have been published, hindering both risk assessment for nanomaterials, as well as the knowledge communication to all involved stakeholders. Thus, DaNa 2.0 serves as a platform to implement trusted knowledge on nanomaterials for an objective discussion.

Recent results on qualification of the RITA components for the ARTEMIS satellite

NASA Astrophysics Data System (ADS)

Bassner, H.; Berg, H.-P.; Kukies, R.

1992-07-01

An improved version of RITA, a radiofrequency ion thruster assembly, is planned to be used as part of the Ion Propulsion Package of an experimental communication satellite, ARTEMIS, now under development in Europe. The Ion Propulsion Package will be used to perform north/south stationkeeping as a responsible subsystem during 10 years of satellite operation. For this purpose, the thrust level of RITA has been increased from 10 to 15 mN. A complete redesign of the Power Supply and Control Unit will simplify the control of the thruster and neutralizer and decrease the number of parts in this electronic unit. The RF generator has been redesigned using latest technology. Results of lifetime and function tests are reported.

New LUX result constrains exotic quark mediators with the vector dark matter

NASA Astrophysics Data System (ADS)

Chen, Chuan-Ren; Li, Ming-Jie

2016-12-01

The scenario of the compressed mass spectrum between heavy quark and dark matter is a challenge for LHC searches. However, the elastic scattering cross-section between dark matter and nuclei in dark matter direct detection experiments can be enhanced with nearly degenerate masses between heavy quarks and dark matter. In this paper, we illustrate such scenario with a vector dark matter, using the latest result from LUX 2016. The mass constraints on heavy quarks can be more stringent than current limits from LHC, unless the coupling strength is very small. However, the compress mass spectrum with allowed tiny coupling strength makes the decay lifetime of heavy quarks longer than the timescale of QCD hadronization.

Information Needs 2000: Results of a Survey of Library Media Specialists.

ERIC Educational Resources Information Center

Ceperley, Patricia E.

School library media specialists in Kentucky, Tennessee, Virginia, and West Virginia were surveyed in April 1990 to determine their perceptions of their training needs as they are being called upon to use the latest information technologies to access, transfer, and store information. The 2,202 responses received represented a response rate of…

Latest Paleocene lithologic and biotic events in neritic deposits of southwestern New Jersey

USGS Publications Warehouse

Gibson, Thomas G.; Bybell, Laurel M.; Owens, James P.

1993-01-01

In the southwestern New Jersey Coastal Plain, four drill holes contain continuous neritic sedimentation across the Paleocene/Eocene boundary (calcareous nannofossil Zone NP 9/NP 10 boundary). Significant lithologic and biotic changes occur in these strata near the top of the Paleocene. Global warming, increased precipitation, and other oceanographic and climatic events that have been recognized in high-latitude, deep-oceanic deposits of the latest Paleocene also influenced mid-latitude, shallow-marine, and terrestrial environments of the western North Atlantic. The diverse, well-preserved calcareous nannofossil flora that is present throughout the entire New Jersey boundary section accurately places these events within the uppermost part of the upper Paleocene Zone NP 9. Several rapid but gradational changes occur within a 1.1-m interval near the top of Zone NP 9. The changes include (1) a change in lithology from glauconitic quartz sand to clay, (2) a change in clay mineral suites from illite/smectite-dominated to kaolinite-dominated, (3) a change in benthic foraminiferal assemblages to a lower diversity fauna suggestive of low-oxygen environments, (4) a significant increase in planktonic foraminiferal abundance, and (5) an increased species turnover rate in marine calcareous nannofossils. Pollen was sparse in the New Jersey drill holes, but terrestrial sporomorph species in Virginia exhibit increased turnover rates at a correlative level. Foraminiferal assemblages and lithology indicate that relative sea level rose in New Jersey at the same time as these late Paleocene events occurred in late Biochron NP 9. The higher sea levels influenced sediment type and absolute abundance of planktonic foraminifers in the deposits. Above the initial increase of kaolinite in the upper part of Zone NP 9, the kaolinite percentage continues to increase, and the maximum kaolinite value occurs in the uppermost part of Zone NP 9. There are few changes in either the sediments or the

[Latest advances in chronic pancreatitis].

PubMed

Domínguez-Muñoz, J Enrique

2014-09-01

This article summarizes some of the recent and clinically relevant advances in chronic pancreatitis. These advances mainly concern the early diagnosis of the disease, the prediction of the fibrosis degree of the gland, the evaluation of patients with asymptomatic hyperenzimemia, the medical and surgical treatment of abdominal pain and the knowledge of the natural history of the autoimmune pancreatitis. In patients with indetermined EUS findings of chronic pancreatitis, a new endoscopic ultrasound examination in the follow-up is of help to confirm or to exclude the disease. Smoking, number of relapses, results of pancreatic function tests and EUS findings allow predicting the degree of pancreatic fibrosis in patients with chronic pancreatitis. Antioxidant therapy has shown to be effective in reducing pain secondary to chronic pancreatitis, although the type and optimal dose of antioxidants remains to be elucidated. Development of intestinal bacterial overgrowth is frequent in patients with chronic pancreatitis, but its impact on symptoms is unknown and deserves further investigations. Finally, autoimmune pancreatitis relapses in about half of the patients with either type 1 or type 2 disease; relapses frequently occur within the first two years of follow-up. Copyright © 2014 Elsevier España, S.L.U. All rights reserved.

Quantification of key long-term risks at CO₂ sequestration sites: Latest results from US DOE's National Risk Assessment Partnership (NRAP) Project

DOE PAGES

Pawar, Rajesh; Bromhal, Grant; Carroll, Susan; ...

2014-12-31

Risk assessment for geologic CO₂ storage including quantification of risks is an area of active investigation. The National Risk Assessment Partnership (NRAP) is a US-Department of Energy (US-DOE) effort focused on developing a defensible, science-based methodology and platform for quantifying risk profiles at geologic CO₂ sequestration sites. NRAP has been developing a methodology that centers round development of an integrated assessment model (IAM) using system modeling approach to quantify risks and risk profiles. The IAM has been used to calculate risk profiles with a few key potential impacts due to potential CO₂ and brine leakage. The simulation results are alsomore » used to determine long-term storage security relationships and compare the long-term storage effectiveness to IPCC storage permanence goal. Additionally, we also demonstrate application of IAM for uncertainty quantification in order to determine parameters to which the uncertainty in model results is most sensitive.« less

Neutrinos in the holographic dark energy model: constraints from latest measurements of expansion history and growth of structure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Jing-Fei; Zhao, Ming-Ming; Li, Yun-He

The model of holographic dark energy (HDE) with massive neutrinos and/or dark radiation is investigated in detail. The background and perturbation evolutions in the HDE model are calculated. We employ the PPF approach to overcome the gravity instability difficulty (perturbation divergence of dark energy) led by the equation-of-state parameter w evolving across the phantom divide w=−1 in the HDE model with c<1. We thus derive the evolutions of density perturbations of various components and metric fluctuations in the HDE model. The impacts of massive neutrino and dark radiation on the CMB anisotropy power spectrum and the matter power spectrum inmore » the HDE scenario are discussed. Furthermore, we constrain the models of HDE with massive neutrinos and/or dark radiation by using the latest measurements of expansion history and growth of structure, including the Planck CMB temperature data, the baryon acoustic oscillation data, the JLA supernova data, the Hubble constant direct measurement, the cosmic shear data of weak lensing, the Planck CMB lensing data, and the redshift space distortions data. We find that ∑ m{sub ν}<0.186 eV (95% CL) and N{sub eff}=3.75{sup +0.28}{sub −0.32} in the HDE model from the constraints of these data.« less

Multi-proxy Paleoclimate and CO2 Reconstruction from the Latest Middle Eocene Sedimentary Fill of a Subarctic Kimberlitic Maar Crater

NASA Astrophysics Data System (ADS)

Reyes, A. V.; Wolfe, A. P.; Royer, D. L.; Greenwood, D. R.; Tierney, J. E.; Doria, G.; Gagen, M. H.; Siver, P.; Westgate, J.

2016-12-01

Eocene paleoclimate reconstructions are rarely accompanied by parallel estimates of CO2, complicating assessment of the equilibrium climate responses to CO2. We reconstruct temperature, precipitation, and CO2 from latest middle Eocene ( 38 Myrs ago) peats in subarctic Canada, preserved in sediments that record infilling of a kimberlite pipe maar crater. Mutual climatic range analyses of pollen, together with oxygen isotope analyses of a-cellulose from unpermineralized wood and inferenecs from branched glycerol diakyl glycerol tetraethers (GDGTs), reveal a high-latitude humid-temperate forest ecosystem with mean annual temperatures (MATs) >17 °C warmer than present, mean coldest month temperatures above 0 °C, and mean annual precipitation 4x present. Metasequoia stomatal indices and gas-exchange modeling produce median CO2 concentrations of 634 and 432 ppm, respectively, with a consensus median estimate of 494 ppm. Reconstructed MATs are >6 °C warmer than those produced by Eocene climate models forced at 560 ppm CO2, underscoring the capacity for exceptional polar amplification of warming and hydrological intensification under relatively modest CO2 concentrations, once both fast and slow feedbacks become expressed.

Diagnostic value of Pentraxin-3 in patients with sepsis and septic shock in accordance with latest sepsis-3 definitions.

PubMed

Hamed, Sonja; Behnes, Michael; Pauly, Dominic; Lepiorz, Dominic; Barre, Max; Becher, Tobias; Lang, Siegfried; Akin, Ibrahim; Borggrefe, Martin; Bertsch, Thomas; Hoffmann, Ursula

2017-08-09

Pentraxin-3 (PTX-3) is an acute-phase protein involved in inflammatory and infectious processes. This study assesses its diagnostic and prognostic value in patients with sepsis or septic shock in a medical intensive care unit (ICU). The study includes 213 ICU patients with clinical criteria of sepsis and septic shock. 77 donors served as controls. Plasma levels of PTX-3, procalcitonin (PCT) and interleukin-6 were measured on day 1, 3 and 8. PTX-3 correlated with higher lactate levels as well as with APACHE II and SOFA scores (p = 0.0001). PTX-3 levels of patients with sepsis or septic shock were consistently significantly higher than in the control group (p ≤ 0.001). Plasma levels were able to discriminate sepsis and septic shock significantly on day 1, 3 and 8 (range of AUC 0.73-0.92, p = 0.0001). Uniform cut-off levels were defined at ≥5 ng/ml for at least sepsis, ≥9 ng/ml for septic shock (p = 0.0001). PTX-3 reveals diagnostic value for sepsis and septic shock during the first week of intensive care treatment, comparable to interleukin-6 according to latest Sepsis-3 definitions. NCT01535534 . Registered 14.02.2012.

Satisfactory Short-Term Results of Navigation-Assisted Gap-Balancing Total Knee Arthroplasty Using Ultracongruent Insert.

PubMed

Yoon, Jung-Ro; Yang, Jae-Hyuk

2018-03-01

The use of highly conforming ultracongruent (UC) polyethylene insert is bone-preserving and became a relatively common alternative to the conventional posterior stabilized total knee arthroplasty (TKA) design. The purpose of this study was to analyze the short-term clinical and radiologic results of UC insert TKA using the navigation-assisted gap-balancing technique. Two hundred thirty-three knees were operated with a mean follow-up period of 8.1 years (minimum of 5 years). Radiologic and clinical outcomes were assessed before operation and at latest follow-up using the Knee Society Score and Western Ontario and McMaster Universities Osteoarthritis Index score. For statistical analysis, paired sample t-test and analysis of variance were used. Significance was considered as P < .05. According to the preoperative deformities (valgus, mild varus, and moderate varus), there were 23 cases (9.9%) of valgus deformity, 180 cases (77.3%) of mild varus deformity, and 30 cases (12.9%) of moderate varus deformity. Overall, the results at mean 8.1 years revealed an improvement in mean Knee Society Score (54 ± 12 to 92 ± 3) and mean Western Ontario and McMaster Universities Osteoarthritis Index scores (62 ± 14 to 17 ± 3). Overall, 220 of 233 cases (94.4%) were in neutral alignment (between -3° and +3°) at latest follow-up. There were no migrating or shifting prosthesis that should be considered as possible failure. There was 0% component revision rate. Navigation-assisted gap-balancing technique using UC insert TKA had satisfactory short-term outcome. Strict gap-balancing technique using the offset-type-force-controlled-spreader-system aided in the satisfactory results. Copyright © 2017 Elsevier Inc. All rights reserved.

New Results from the DREAM project

NASA Astrophysics Data System (ADS)

Meoni, E.; Dream Collaboration

2011-06-01

Dual-Readout calorimetry is a promising new technique for high precision measurements of hadronic showers and jets. The DREAM Collaboration is exploiting the possibilities offered by this technique, a key aspect of which is the simultaneous measurement of the scintillation light and the Cerenkov light generated in the shower development process. By comparing these two signals, the electromagnetic shower fraction can be measured event by event, eliminating the effects of its fluctuations, that are the dominant contribution to the hadronic energy resolution. In the first detector of this type the two signals were provided by two independent active media: scintillating fibers and quartz fibers. In follow-up studies, we have explored the possibilities of heavy crystals such as BGO and PbWO4. The use of homogeneous detectors has the advantage that it eliminates the effects of fluctuations that limit the resolution of the fiber calorimeter: sampling fluctuations and quantum fluctuations in the Cerenkov signals. A very important tool turnes out to be a detailed measurement of the time structure of the signals. In this paper, the latest results of this project will be presented.

Out-of-plane buckling of pantographic fabrics in displacement-controlled shear tests: experimental results and model validation

NASA Astrophysics Data System (ADS)

Barchiesi, Emilio; Ganzosch, Gregor; Liebold, Christian; Placidi, Luca; Grygoruk, Roman; Müller, Wolfgang H.

2018-01-01

Due to the latest advancements in 3D printing technology and rapid prototyping techniques, the production of materials with complex geometries has become more affordable than ever. Pantographic structures, because of their attractive features, both in dynamics and statics and both in elastic and inelastic deformation regimes, deserve to be thoroughly investigated with experimental and theoretical tools. Herein, experimental results relative to displacement-controlled large deformation shear loading tests of pantographic structures are reported. In particular, five differently sized samples are analyzed up to first rupture. Results show that the deformation behavior is strongly nonlinear, and the structures are capable of undergoing large elastic deformations without reaching complete failure. Finally, a cutting edge model is validated by means of these experimental results.

Latest Developments in SLD Scaling

NASA Technical Reports Server (NTRS)

Tsao, Jen-Ching; Anderson, David N.

2006-01-01

Scaling methods have been shown previously to work well for super cooled large droplet (SLD) main ice shapes. However, feather sizes for some conditions have not been well represented by scale tests. To determine if there are fundamental differences between the development of feathers for appendix C and SLD conditions, this study used time-sequenced photographs, viewing along the span of the model during icing sprays. An airspeed of 100 kt, cloud water drop MVDs of 30 and 140 microns, and stagnation freezing fractions of 0.30 and 0.50 were tested in the NASA Glenn Icing Research Tunnel using an unswept 91-cm-chord NACA0012 airfoil model mounted at 0deg AOA. The photos indicated that the feathers that developed in a distinct region downstream of the leading-edge ice determined the horn location and angle. The angle at which feathers grew from the surface were also measured; results are shown for an airspeed of 150 kt, an MVD of 30 microns, and stagnation freezing fractions of 0.30 to 0.60. Feather angles were found to depend strongly on the stagnation freezing fraction, and were independent of either chordwise position on the model or time into the spray. Feather angles also correlated well with horn angles. For these tests, there did not appear to be fundamental differences between the physics of SLD and appendix C icing; therefore, for these conditions similarity parameters used for appendix C scaling appear to be valid for SLD scaling as well. Further investigation into the cause for the large feather structures observed for some SLD conditions will continue.

Long-term changes in composition and distribution patterns in the Iberian herpetofaunal communities since the latest Pleistocene

NASA Astrophysics Data System (ADS)

Bisbal-Chinesta, Josep Francesc; Blain, Hugues-Alexandre

2018-03-01

The climate has undergone significant changes since the end of the Last Glacial Maximum and in the course of the Holocene, parallel to important cultural transformations and migrations in the human communities. The faunal record has also suffered the effects of climate change. Amphibians and reptiles in particular have been shown to be highly sensitive because they are very susceptible to temperature alterations due to their ectothermy. This research presents the first approach to the Iberian paleobiogeography of the different species of amphibians and reptiles from the Late Pleistocene (MIS3) to present times, based on a comparative synthesis of the latest research published in recent years and the fossil record of the 58 archaeo-paleontological sites with significant assemblages. The paleoherpetofaunal associations make it possible to establish two major biotic regions during the Late Pleistocene. The first biotic region was located in the center and south of the Iberian Peninsula, with thermophilic species as the most representative taxa. The second biotic region was formed by the Atlantic-Cantabrian facade and the northeast Iberian area, dominated by hygrophilous and Euro-Siberian species, with an absence of Mediterranean species. After the Last Glacial Maximum there was an unprecedented concurrence in the northern Iberian Peninsula of autochthonous taxa from that area with thermophilic species. In the early Holocene, new species with no previous record in the Iberian Peninsula entered northern Iberia from eastern Mediterranean refugia. Finally, the introduction of North African species was the last significant biogeographical change during the Middle-Late Holocene.

Paleoclimatic Reconstructions From Plant Macrofossils For The Last Glacial Maximum, Middle Holocene, And Latest Holocene In The American Southwest

NASA Astrophysics Data System (ADS)

Thompson, R. S.; Anderson, K.; Pelltier, R.; Strickland, L. E.; Shafer, S. L.; Bartlein, P. J.

2013-12-01

Fossil plant remains preserved in a variety of geologic settings provide direct evidence of where individual species lived in the past, and there are long-established methods for paleoclimatic reconstructions based on comparisons between modern and past geographic ranges of plant species. In principle, these methods use relatively straightforward procedures that frequently result in what appear to be very precise estimates of past temperature and moisture conditions. The reconstructed estimates can be mapped for specific time slices for synoptic-scale reconstructions for data-model comparisons. Although paleobotanical data can provide apparently precise estimates of past climatic conditions, it is difficult to gauge the associated uncertainties. The estimates may be affected by the choice of modern calibration data, reconstruction methods employed, and whether the climatic variable under consideration is an important determinant of the distributions of the species being considered. For time-slice reconstructions, there are also issues involving the adequacy of the spatial coverage of the fossil data and the degree of variability through time. To examine some of these issues, we estimated annual precipitation and summer and winter temperatures for the Last Glacial Maximum (LGM, 21000 × 1000 yr BP), Middle Holocene (MH, 6000 × 500 yr BP), and Latest Holocene (LH, the last 500 yrs), based on the application of four quantitative approaches to paleobotanical assemblages preserved in packrat middens in the American Southwest. Our results indicate that historic variability and difficulties in interpolating climatic values to fossil sites may impose ranges of uncertainties of more than × 1°C for temperature and × 50 mm for annual precipitation. Climatic estimates based on modern midden assemblages generally fall within these ranges, although there may be biases that differ regionally. Samples of similar age and location provide similar climatic estimates, and the four

Review of fundamental physics results with the MAGIC telescopes

NASA Astrophysics Data System (ADS)

Rico, Javier

2017-01-01

The MAGIC Cherenkov telescopes are powerful tools for the exploration of the Physics frontiers, addressing topics such as the nature of dark matter and its distribution in the Universe, or the search for quantum gravitational effects in photon propagation. Since the beginning of operations in 2004, MAGIC has studied these questions thanks to hundreds of hours of observations of different targets, and has produced several high-impact results. Those include, significantly, the most constraining limits to the WIMP annihilation cross-section for particle masses above few hundred GeV, from observations of dwarf spheroidal (dSph) satellite galaxies. More recently, we have completed a combined analysis of MAGIC and Fermi-LAT observations of dSphs, obtaining limits for dark matter particle masses between 10 GeV and 100 TeV - the widest mass range ever explored by a single gamma-ray analysis - and improving the previously published Fermi-LAT and MAGIC results by up to a factor of two at certain masses. In this talk, I present an overview of the status and results of MAGIC Fundamental Physics projects, including our latest results concerning searches for Lorentz Invariance violation (LIV), and dark matter searches. I will propose the use of the framework developed for the MAGIC/Fermi-LAT joint analysis for the combination of results from the current generation of gamma-ray and neutrino detectors.

Implementation of Gender Studies Results into Teacher Training in Germany: Challenges and Perspectives

ERIC Educational Resources Information Center

Gryvkova, Olena

2017-01-01

Introduction of gender-specific approaches in education is a new step in the development of pedagogical anthropology. Pedagogy as a fundamental complex discipline, which is based on the latest achievements of knowledge about a human, cannot stand aside the transformational modifications of the societies and cannot help responding to their…

Results of the Survey on Program Management in Education Abroad. Executive Summary

ERIC Educational Resources Information Center

Forum on Education Abroad, 2007

2007-01-01

In an effort to assess the latest practices in the field of education abroad and provide information to its members, the field of education abroad, and the media, the Forum on Education Abroad's Data Committee, under the leadership of its chair, Kim Kreutzer, designed a survey on study abroad program management. The Data Committee was assisted in…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oliveira Santos, F. de; Collaboration: E521S Collaboration

The properties of the low lying states of {sup 15}F were studied by measuring the resonant elastic scattering of an {sup 14}O radioactive beam on protons. This experiment was performed at GANIL with a post-accelerated beam produced by the SPIRAL1 facility. We confirm the existence of a second excited state in {sup 15}F with a narrow width, which may seem particularly surprising for a state located above the Coulomb barrier.

S3 targets monitoring with an electron gun

NASA Astrophysics Data System (ADS)

Kallunkathariyil, J.; Stodel, Ch.; Marry, C.; Frémont, G.; Bastin, B.; Piot, J.; Clément, E.; Le Moal, S.; Morel, V.; Thomas, J.-C.; Kamalou, O.; Spitaëls, C.; Savajols, H.; Vostinar, M.; Pellemoine, F.; Mittig, W.

2018-05-01

The monitoring of targets under irradiation was investigated using a 20 keV electron beam. An integrated and automated electron beam deflection was developed allowing a monitoring over the whole surface of target materials. Thus, local defects could be identified on-line during an experiment performed at GANIL involving different materials irradiated with a focused krypton beam at 10.5 MeV/u. Performances of this target monitoring system are presented in this paper.

GHX, Broadlane form latest e-commerce linkup.

PubMed

2002-08-01

Broadlane agreed in June to connect its electronic commerce system to the supplier-owned site run by GHX. As a result, contract compliance could either improve or be more easily evaded, depending on hospitals' response to the wider choice of suppliers.

Environmental change and cultural adaptation in the southern Caucasus: latest results from Aghitu-3 Cave, Armenia

NASA Astrophysics Data System (ADS)

Kandel, Andrew; Gasparyan, Boris; Bruch, Angela; Nahapetyan, Samvel; Weissbrod, Lior

2014-05-01

The well stratified locality of Aghitu-3 Cave in the southern Caucasus provides a glimpse into the daily lives of the earliest known Upper Paleolithic inhabitants of Armenia. With three main phases of sedimentation serving as a backdrop to human settlement, the locality provides an excellent stratigraphic record documenting environmental change between about 40,000 and 24,000 cal BP. From the end of MIS 3 with its warm and humid climate, early modern humans made use of the cave with increasing frequency during the colder and drier MIS 2. People produced stone tools from obsidian and chert, hunted medium sized ungulates and equids, and used bone tools to make clothing. The archaeological finds from Aghitu-3 suggest that mobile groups of Upper Paleolithic people used this high altitude (1601 m) cave as a seasonal camp with increasing frequency over time. Carnivores and birds of prey also made use of the cave, likely when humans were not present. The paleoenvironmental indicators confirm a warmer and more humid climate during the first sedimentary phase between about 40,000 and 33,000 cal BP. At about 35,000 cal BP the pollen profile indicates a vegetation of mixed deciduous and steppic species. The presence of green algae supports the interpretation that more humid conditions prevailed. Geological analysis indicates uniform, fine-grained deposition along the banks of a slow moving stream. This and the general lack of rock falls confirm a warmer and more humid climate. The spectrum of micromammals shows a higher proportion of golden hamster, also supporting a favorable climate. However, starting about 33,000 cal BP, we observe a second phase of deposition characterized by coarser sediment with evidence of rill washing, cycles of erosion and frequent large basalt rock falls. These observations suggest a dramatic cooling trend as the climate began to deteriorate. The third depositional phase starts about 29,000 cal BP and is marked by mainly aeolian deposition consisting of fine silt horizons with alternating layers of frost shattered basalt slabs. Pollen shows a change to boreal forest, and the increased presence of pika among the micromammals suggests colder and more barren conditions than today. The wide spectrum of micromammals further points to their likely accumulation by a non-selective raptor such as eagle owl. Fish remains of brown trout confirm the presence of a significant fluvial corridor, likely the nearby Vorotan River. This agrees with the charcoal remains identified thus far, which have the signature of a riparian woodland. The sedimentary sequence ends here, truncated at about 24,000 cal BP by late Holocene deposits of anthropogenic origin.

[Analysis of prevention of diseases in travellers on the basis of latest results in travel medicine].

PubMed

Felkai, Péter

2008-09-07

When we survey the possibilities of prevention in travel medicine, it is soon detected that the "classical" or "infectology-oriented" approach of prevention (vaccination - chemoprophylaxis - pretravel advice) cannot respond to all peritravel medical problems. These newly arisen challenges require a new, complex outlook for travel medicine, mainly in the field of prevention, treatment and management of travel-related illnesses. Although travellers are still exposed to various infectious diseases, which are mostly preventable by the primary prevention methods (biomedical prophylaxis), the majority of travellers suffer from non-infectious diseases and fall ill or suffer accident by other, travel-relating factors. Moreover, the predominant destination is Europe for an average Hungarian traveller. The travellers, whose destination is not any tropical or developing country, i.e. adventure travellers, people in extreme sports, chronic patients all require same-level peritravel (prevention-oriented) advice, too. Thus besides vaccination, helmets, salt-tablets, medical kit, mobile oxygenator must belong to a travel doctors' arsenal. We also have to mention the travellers' acute illness/accident abroad, travellers who require repatriation, and also the appropriate travel insurance policy which should be worked out following evidence-based medical considerations. The above-mentioned complex task requires not only a broad-spectrum, multidisciplinary knowledge, but an appropriate co-operation between the travel medicine physician, the general practitioner of the patient, and the doctor of the insurance company. But, above all, we have to redefine the topic of travel medicine, its subspecialties and role in the three-level (primary, secondary and tertiary) prevention. We have to redefine the different prevention levels and the used methods relating to the different subdisciplines of travel medicine. Upon the recent scientific researches, we can lay down four topics of travel medicine: biomedical prophylaxis, assistance medicine, wilderness medicine and travel-insurance medicine. This "four-leaf clover" model is fit for the complex approach of the newly generated peritravel medical problems, both in Hungary and abroad. This kind of approach makes the doctor (who contacted the travellers at any respect: travel medicine specialists, GPs, occupational medicine specialists, insurance physicians) able to participate in the peritravel treatment or pretravel advising of travellers. The basic ideas of the prevention levels have to be established in each subdiscipline of travel medicine. Another urgent task is to establish a countrywide network of travel medicine facilities as well as the organisation of gradual and postgraduate education of physicians and professionals. We have to implement new forms and methods during training. Travel advising and peritravel prevention require well and continuously trained doctors.

Neutron-rich nuclei produced at zero degrees in damped collisions induced by a beam of 18O on a 238U target

NASA Astrophysics Data System (ADS)

Stefan, I.; Fornal, B.; Leoni, S.; Azaiez, F.; Portail, C.; Thomas, J. C.; Karpov, A. V.; Ackermann, D.; Bednarczyk, P.; Blumenfeld, Y.; Calinescu, S.; Chbihi, A.; Ciemala, M.; Cieplicka-Oryńczak, N.; Crespi, F. C. L.; Franchoo, S.; Hammache, F.; Iskra, Ł. W.; Jacquot, B.; Janssens, R. V. F.; Kamalou, O.; Lauritsen, T.; Lewitowicz, M.; Olivier, L.; Lukyanov, S. M.; Maccormick, M.; Maj, A.; Marini, P.; Matea, I.; Naumenko, M. A.; de Oliveira Santos, F.; Petrone, C.; Penionzhkevich, Yu. E.; Rotaru, F.; Savajols, H.; Sorlin, O.; Stanoiu, M.; Szpak, B.; Tarasov, O. B.; Verney, D.

2018-04-01

Cross sections and corresponding momentum distributions have been measured for the first time at zero degrees for the exotic nuclei obtained from a beam of 18O at 8.5 MeV/A impinging on a 1 mg/cm2238U target. Sizable cross sections were found for the production of exotic species arising from the neutron transfer and proton removal from the projectile. Comparisons of experimental results with calculations based on deep-inelastic reaction models, taking into account the particle evaporation process, indicate that zero degree is a scattering angle at which the differential reaction cross section for production of exotic nuclei is at its maximum. This result is important in view of the new generation of zero degrees spectrometers under construction, such as the S3 separator at GANIL, for example.

Research on plant utilization and adaptation to environment of human in Guangxi of Southern China during the latest 30000 years

NASA Astrophysics Data System (ADS)

Wu, Y.; Xie, G.

2017-12-01

It is an important scientific problem in the study of the relationship between man and land to select the key areas and important periods of human evolution. In the latest 30 thousand years, it is an important period for late Pleistocene climate change, which has a profound impact on human evolution. Southern China including Guangxi has a unique geographical landscape pattern and unique vegetation and climate background, which is not only an important channel for the diffusion and migration of ancient humans but also an ideal refuge to avoid climate changes. It preserved the rich archaeological remains of the evolution and development of human beings, and provided a rare place for the adaptive strategies of human survival and early the environment. In this paper, Yahuai cave site in Guangxi will be selected for investigation. We will analyze the continuous accumulation of ancient human remains, and utilized AMS14C to reconstruct the dating framework. We will also extract the plant information and environment of the site through pollen, phytolith, grain and starch grains. We will further explore the succession mode of utilization of plant resources and its relationship with climate change and reveal the adaptability to the environment and strategy.

Statistical assessment and hydrological utility of the latest multi-satellite precipitation analysis IMERG in Ganjiang River basin

NASA Astrophysics Data System (ADS)

Li, Na; Tang, Guoqiang; Zhao, Ping; Hong, Yang; Gou, Yabin; Yang, Kai

2017-01-01

This study aims to statistically and hydrologically assess the hydrological utility of the latest Integrated Multi-satellitE Retrievals from Global Precipitation Measurement (IMERG) multi-satellite constellation over the mid-latitude Ganjiang River basin in China. The investigations are conducted at hourly and 0.1° resolutions throughout the rainy season from March 12 to September 30, 2014. Two high-quality quantitative precipitation estimation (QPE) datasets, i.e., a gauge-corrected radar mosaic QPE product (RQPE) and a highly dense network of 1200 rain gauges, are used as the reference. For the implementation of the study, first, we compare IMERG product and RQPE with rain gauge-interpolated data, respectively. The results indicate that both remote sensing products can estimate precipitation fairly well over the basin, while RQPE significantly outperforms IMERG product in almost all the studied cases. The correlation coefficients of RQPE (CC = 0.98 and CC = 0.67) are much higher than those of IMERG product (CC = 0.80 and CC = 0.33) at basin and grid scales, respectively. Then, the hydrological assessment is conducted with the Coupled Routing and Excess Storage (CREST) model under multiple parameterization scenarios, in which the model is calibrated using the rain gauge-interpolated data, RQPE, and IMERG products respectively. During the calibration period (from March 12 to May 31), the simulated streamflow based on rain gauge-interpolated data shows the highest Nash-Sutcliffe coefficient efficiency (NSCE) value (0.92), closely followed by the RQPE (NSCE = 0.84), while IMERG product performs barely acceptable (NSCE = 0.56). During the validation period (from June 1 to September 30), the three rainfall datasets are used to force the CREST model based on all the three calibrated parameter sets (i.e., nine combinations in total). RQPE outperforms rain gauge-interpolated data and IMERG product in all validation scenarios, possibly due to its advantageous capability

Modeling of sub-ionospheric VLF signal anomalies associated with precursory effects of the latest earthquakes in Nepal

NASA Astrophysics Data System (ADS)

Sasmal, Sudipta; Chakrabarti, Sandip Kumar; Palit, Sourav; Chakraborty, Suman; Ghosh, Soujan; Ray, Suman

2016-07-01

We present the nature of perturbations in the propagation characteristics of Very Low Frequency (VLF) signals received at Ionospheric & Earthquake Research Centre (IERC) (Lat. 22.50 ^{o}N, Long. 87.48 ^{o}E) during and prior to the latest strong earthquakes in Nepal on 12 May 2015 at 12:50 pm local time (07:05 UTC) with a magnitude of 7.3 and depth 18 km at southeast of Kodari. The VLF signal emitted from JJI transmitter (22.2kHz) in Japan (Lat. 32.08 ^{o}N, Long. 130.83 ^{o}E) shows strong shifts in sunrise and sunset terminator times towards nighttime beginning three to four days prior to the earthquake. The shift in terminator times is numerically simulated using Long Wavelength Propagation Capability (LWPC) code. Electron density variation as a function of height is calculated for seismically quiet days using the Wait's exponential profile and it matches with the IRI model. The perturbed electron density is calculated using the effective reflection height (h') and sharpness parameter (β) and the rate of ionization due to earthquake is being obtained by the equation of continuity for ionospheric D-layer. We compute the ion production and recombination profiles during seismic and non-seismic conditions incorporating D-region ion chemistry processes and calculate the unperturbed and perturbed electron density profile and ionization rate at different heights which matches with the exponential profile. During the seismic condition, for both the cases, the rate of ionization and the electron density profile differ significantly from the normal values. We interpret this to be due to the seismo-ionospheric coupling processes.

Latest Early Pleistocene remains of Lynx pardinus (Carnivora, Felidae) from the Iberian Peninsula: Taxonomy and evolutionary implications

NASA Astrophysics Data System (ADS)

Boscaini, Alberto; Alba, David M.; Beltrán, Juan F.; Moyà-Solà, Salvador; Madurell-Malapeira, Joan

2016-07-01

The Iberian lynx (Lynx pardinus) is a critically endangered felid that, during the last fifty years, has been subject to an intensive conservation program in an attempt to save it from extinction. This species is first recorded at ca. 1.7-1.6 Ma (late Villafranchian, late Early Pleistocene) in NE Iberian Peninsula, roughly coinciding with the large faunal turnover that occurred around the middle to late Villafranchian boundary. Here we describe the largest collection of L. pardinus remains available to date from the Iberian late Early Pleistocene (Epivillafranchian), including localities from the Vallparadís Section (Vallès-Penedès Basin, NE Iberian Peninsula) and Cueva Victoria (Cartagena, SE Iberian Peninsula). The morphology and biometry of the studied material attests to the widespread occurrence of L. pardinus in the Mediterranean coast of the Iberian Peninsula since the latest Early Pleistocene, i.e., about 0.5 million years earlier than it was generally accepted (i.e., at the beginning of the Middle Pleistocene). Based on the features observed in the large sample studied in this paper, we conclude that Lynx spelaeus is a junior synonym of L. pardinus and further propose to assign all the Epivillafranchian and younger fossil lynxes from SW Europe to the extant species L. pardinus. Due to the arrival of the Eurasian lynx (Lynx lynx) into Europe at the beginning of the Late Pleistocene, the attribution of specimens younger than MIS 5e to either this species or L. pardinus solely on morphological grounds has proven equivocal. Here we discuss the main diagnostic features of both species of European lynxes and further review their evolutionary history and paleobiogeography throughout the Pleistocene.

Ecomorphological characterization of murines and non-arvicoline cricetids (Rodentia) from south-western Europe since the latest Middle Miocene to the Mio-Pliocene boundary (MN 7/8–MN13)

PubMed Central

Kimura, Yuri; Blanco, Fernando; Menéndez, Iris; Álvarez-Sierra, María A.; Hernández Fernández, Manuel

2017-01-01

Rodents are the most speciose group of mammals and display a great ecological diversity. Despite the greater amount of ecomorphological information compiled for extant rodent species, studies usually lack of morphological data on dentition, which has led to difficulty in directly utilizing existing ecomorphological data of extant rodents for paleoecological reconstruction because teeth are the most common or often the only micromammal fossils. Here, we infer the environmental ranges of extinct rodent genera by extracting habitat information from extant relatives and linking it to extinct taxa based on the phenogram of the cluster analysis, in which variables are derived from the principal component analysis on outline shape of the upper first molars. This phenotypic “bracketing” approach is particularly useful in the study of the fossil record of small mammals, which is mostly represented by isolated teeth. As a case study, we utilize extinct genera of murines and non-arvicoline cricetids, ranging from the Iberoccitanian latest middle Miocene to the Mio-Pliocene boundary, and compare our results thoroughly with previous paleoecological reconstructions inferred by different methods. The resultant phenogram shows a predominance of ubiquitous genera among the Miocene taxa, and the presence of a few forest specialists in the two rodent groups (Murinae and Cricetidae), along with the absence of open environment specialists in either group of rodents. This appears to be related to the absence of enduring grassland biomes in the Iberian Peninsula during the late Miocene. High consistency between our result and previous studies suggests that this phenotypic “bracketing” approach is a very useful tool. PMID:28966888

ATON (Autonomous Terrain-based Optical Navigation) for exploration missions: recent flight test results

NASA Astrophysics Data System (ADS)

Theil, S.; Ammann, N.; Andert, F.; Franz, T.; Krüger, H.; Lehner, H.; Lingenauber, M.; Lüdtke, D.; Maass, B.; Paproth, C.; Wohlfeil, J.

2018-03-01

Since 2010 the German Aerospace Center is working on the project Autonomous Terrain-based Optical Navigation (ATON). Its objective is the development of technologies which allow autonomous navigation of spacecraft in orbit around and during landing on celestial bodies like the Moon, planets, asteroids and comets. The project developed different image processing techniques and optical navigation methods as well as sensor data fusion. The setup—which is applicable to many exploration missions—consists of an inertial measurement unit, a laser altimeter, a star tracker and one or multiple navigation cameras. In the past years, several milestones have been achieved. It started with the setup of a simulation environment including the detailed simulation of camera images. This was continued by hardware-in-the-loop tests in the Testbed for Robotic Optical Navigation (TRON) where images were generated by real cameras in a simulated downscaled lunar landing scene. Data were recorded in helicopter flight tests and post-processed in real-time to increase maturity of the algorithms and to optimize the software. Recently, two more milestones have been achieved. In late 2016, the whole navigation system setup was flying on an unmanned helicopter while processing all sensor information onboard in real time. For the latest milestone the navigation system was tested in closed-loop on the unmanned helicopter. For that purpose the ATON navigation system provided the navigation state for the guidance and control of the unmanned helicopter replacing the GPS-based standard navigation system. The paper will give an introduction to the ATON project and its concept. The methods and algorithms of ATON are briefly described. The flight test results of the latest two milestones are presented and discussed.

Studying Nuclear Structure at the extremes with S3

NASA Astrophysics Data System (ADS)

Piot, Julien

2018-05-01

The in-depth study of the regions of Superheavy elements and the proton drip line around 100Sn are two major challenges of today's Nuclear Physics. Performing detailed spectroscopic studies on these nuclei requires a significant improvement of our detection capabilities. The Super-Separator-Spectrometer S3 is part of the SPIRAL2 facility at GANIL. Its aim is to use the high stable beam currents provided by the new LINAC to reach rare isotopes by fusion-evaporation.

Latest developments of 10μm pitch HgCdTe diode array from the legacy to the extrinsic technology

NASA Astrophysics Data System (ADS)

Péré-Laperne, Nicolas; Berthoz, Jocelyn; Taalat, Rachid; Rubaldo, Laurent; Kerlain, Alexandre; Carrère, Emmanuel; Dargent, Loïc.

2016-05-01

Sofradir recently presented Daphnis, its latest 10 μm pitch product family. Both Daphnis XGA and HD720 are 10μm pitch mid-wave infrared focal plane array. Development of small pixel pitch is opening the way to very compact products with a high spatial resolution. This new product is taking part in the HOT technology competition allowing reductions in size, weight and power of the overall package. This paper presents the recent developments achieved at Sofradir to make the 10μm pitch HgCdTe focal plane array based on the legacy technology. Electrical and electro-optical characterizations are presented to define the appropriate design of 10μm pitch diode array. The technological tradeoffs are explained to lower the dark current, to keep high quantum efficiency with a high operability above 110K, F/4. Also, Sofradir recently achieved outstanding Modulation Transfer Function (MTF) demonstration at this pixel pitch, which clearly demonstrates the benefit to users of adopting 10μm pixel pitch focal plane array based detectors. Furthermore, the HgCdTe technology has demonstrated an increase of the operating temperature, plus 40K, moving from the legacy to the P-on-n one at a 15μm pitch in mid-wave band. The first realizations using the extrinsic P-on-n technology and the characterizations of diodes with a 10μm pitch neighborhood will be presented in both mid-wave and long-wave bands.

Survey of Recent Results from the PHOBOS Experiment at RHIC

NASA Astrophysics Data System (ADS)

Roland, Christof; Back, B. B.; Baker, M. D.; Barton, D. S.; Betts, R. R.; Ballintijn, M.; Bickley, A. A.; Bindel, R.; Budzanowski, A.; Busza, W.; Carroll, A.; Decowski, M. P.; Garcia, E.; George, N.; Gulbrandsen, K.; Gushue, S.; Halliwell, C.; Hamblen, J.; Heintzelman, G. A.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Hołyński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Katzy, J.; Khan, N.; Kucewicz, W.; Kulinich, P.; Kuo, C. M.; Lin, W. T.; Manly, S.; McLeod, D.; Michałowski, J.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Park, I. C.; Pernegger, H.; Reed, C.; Remsberg, L. P.; Reuter, M.; Roland, C.; Roland, G.; Rosenberg, L.; Sarin, P.; Sawicki, P.; Skulski, W.; Steadman, S. G.; Steinberg, P.; Stephans, G. S. F.; Stodulski, M.; Sukhanov, A.; Tang, J.-L.; Teng, R.; Trzupek, A.; Vale, C.; van Nieuwenhuizen, G. J.; Verdier, R.; Wadsworth, B.; Wolfs, F. L. H.; Wosiek, B.; Woźniak, K.; Wuosmaa, A. H.; Wysłouch, B.

2002-10-01

We present an overview of the latest results for interactions of Au+Au ions at center-of-mass energies of √SNN of 56, 130 and 200 GeV obtained by the PHOBOS collaboration at the Relativistic Heavy Ion Collider (RHIC). These data have allowed us to perform an extensive study of the pseudorapidity density of primary charged particles as a function of incident energy, centrality and pseudorapidity. Our results show a non-trivial evolution of particle densities with both centrality and collision energy, reaching significantly higher values per participating nucleon than at lower energies or in nucleon-nucleon collisions. Further we present results on the azimuthal asymmetry of particle production observed in the √SNN of 130 GeV data set. The observed strong event anisotropy of v2max > 0.06, reaching beyond the value predicted in hadronic cascade models, indicates a closer approach to local thermal equilibration than at lower collision energies. The measured antiparticle-particle ratios of production rates for pions kaons and protons in central Au+Au interactions at √SNN of 130 GeV are compatible with predictions from statistical models, showing an approach to a baryon free region in mid-rapidity with the increase in collision energy.

New results of microfaunal and geochemical investigations in the Permian-Triassic boundary interval from the Jadar Block (NW Serbia)

NASA Astrophysics Data System (ADS)

Sudar, Milan N.; Kolar-Jurkovšek, Tea; Nestell, Galina P.; Jovanović, Divna; Jurkovšek, Bogdan; Williams, Jeremy; Brookfield, Michael; Stebbins, Alan

2018-04-01

Detail results of microfaunal, sedimentological and geochemical investigations are documented from a newly discovered section of the Permian-Triassic boundary (PTB) interval in the area of the town of Valjevo (northwestern Serbia). The presence of various and abundant microfossils (conodonts, foraminifers, and ostracodes) found in the Upper Permian "Bituminous limestone" Formation enabled a determination of the Changhsingian Hindeodus praeparvus conodont Zone. This paper is the first report of latest Permian strata from the region, as well as from all of Serbia, where the PTB interval sediments have been part of a complex/integrated study by means of biostratigraphy and geochemistry.

Tectono-sedimentary features in the Yap subduction zone, Western Pacific: constraints from latest integrated geophysical survey

NASA Astrophysics Data System (ADS)

Dong, D.; Zhang, G.; Bai, Y.; Fan, J.; Zhang, Z.

2017-12-01

The Yap subduction zone, western Pacific, is a typical structure related to the ridge subduction, but comparative shortage of the geophysical data makes the structural details unknown in this area. In this study, we present the latest and high-quality multi-beam swath bathymetry and multi-channel seismic data acquired synchronously in the year 2015 across the Yap subduction zone. Multichannel seismic and multi-beam data are mainly applied to investigate the topography of major tectonic units and stratigraphic structure in the Yap subduction zone and discuss the tectonic characteristics controlled by ridge subduction. It suggests that, Parece Vela Basin, as the regional sedimentary center, developed sedimentary layers nearly 800 meters thick. On the contrast, the horizontal sedimentary layers were not obviously identified in the Yap trench, where subduction erosion occurred. Caroline ridge changed the tectonic characteristics of subduction zone, and influenced magmatism of the Yap arc because of the special topography. The seismic profile clearly reveals landslide deposits at the upper slope break of the forearc, north of the Yap Island, which was identified as the fault notch denoting a lithological boundary in previous work. Detailed topography and geological structure of horst and graben in the north of Yap are depicted, and topographic high of Caroline ridge is supposed to bring greater bending and tension and the subsequent horst and graben belt. Multichannel seismic evidence has been provided for interpreting the expansion of Sorol Trough and its inferred age. A modified model for the Yap subduction zone evolution is proposed, incorporating three major tectonic events: proto-Yap Arc rupture in the Oligocene, collision of the Caroline Ridge and the Yap Trench in the Late Oligocene or Middle Miocene, and onset of the Sorol Trough rifting in the Late Miocene. Acknowledge: This study was supported by the Strategic Priority Research Program of the Chinese Academy

Evidence for rapid climate change in North America during the latest Paleocene thermal maximum: oxygen isotope compositions of biogenic phosphate from the Bighorn Basin (Wyoming)

NASA Astrophysics Data System (ADS)

Fricke, Henry C.; Clyde, William C.; O'Neil, James R.; Gingerich, Philip D.

1998-07-01

Oxygen isotope records of Cenozoic sea water temperatures indicate that a rapid warming event known as the Latest Paleocene Thermal Maximum (LPTM) occurred during the otherwise gradual increase in world temperatures during the Late Paleocene and Early Eocene. Oxygen isotope analysis of the carbonate and phosphate components of hydroxyapatite found in mammalian tooth enamel and body scales of river-dwelling fish from the Bighorn Basin in Wyoming were made to investigate corresponding changes in the terrestrial climate. A comparison of carbonate and phosphate isotope data from modern and fossil material indicates that some diagenetic alteration of the fossil material has occurred, although systematically larger intra-tooth ranges in the oxygen isotope composition of carbonate indicate that it is more likely to have been affected than phosphate. Carbonate and phosphate from the ecologically diverse mammals and fishes both record a shift to higher oxygen isotope ratios at the same time and of the same duration as the LPTM. These shifts reflect a change in the isotopic composition of regional precipitation, which in turn provides the first evidence for continental climate change during the LPTM. Assuming the present-day relation between the oxygen isotope composition of precipitation and temperature applies to conditions in the past, and that animal physiology and behavior is relatively invariant over time, the isotopic shift is equivalent to an increase of surface temperature in western North America of several degrees. This result is consistent with the magnitude of high-latitude ocean warming, and provides a basis for relating marine and terrestrial oxygen isotope records to records of terrestrial biotic change.

[Proximal femoral varus osteotomy in adults after developmental dysplasia of the hip: long-term results].

PubMed

Rozkydal, Z; Janíček, P; Otiepka, P

2010-01-01

The aim of this retrospective study was to assess the results of varus osteotomy of the proximal femur in adults with coxa valga after developmental dysplasia of the hip (DDH) and to evaluate the efficacy of this method. Thirty hips in 28 patients treated by proximal femoral varus osteotomy in the period from 1983 to 1990 were evaluated. The indication for surgery involved coxa valga (145°-168°) with grade I- III of osteoarthritis and mild acetabular dysplasia. The patient group comprised twenty six women and two men with an average age of 28 years (18 to 42) at the time of surgery. The mean follow-up was 22 years (19 to 26). The preoperative radiographic examination included an AP view of the pelvis, AP views of the hip in neutral and in frog-leg position and AP views of the hip in 30° of abduction and neutral rotation. Varus osteotomy was indicated when the best position of the hip joint was achieved in abduction. The procedure was performed according to M. Müller. Hip assessment was based on the grade of osteoarthritis, CCD angle, Wiberg angle and AHI index. The results were statistically evaluated using the life table analysis of clinical survivorship of osteotomy and the Kaplan- Meier curve. Clinical failure was defined as conversion of osteotomy to total hip replacement (THR). At the latest follow-up of 22 years on the average, 18 patients (19 hips) still had osteotomy and 10 patients (11 hips) had undergone conversion to THR. The life table analysis showed the cumulative proportion of osteotomy with a clinical survivorship of 0.97 at 5 years, 0.75 at 10 and 15 years, and 0.68 at 20 and 25 years after surgery. The cumulative rate of clinical survivorship of osteotomy, as shown by the Kaplan-Meier curve, was 0.89 at 10 years, 0.75 at 20 years and 0.67 at 25 years after surgery. Nineteen patients were satisfied with the osteotomy outcome. The median of Harris hip scores in the patients with osteotomy was 48 points before surgery and 78 points at the latest

Heavy ion irradiation of crystalline water ice. Cosmic ray amorphisation cross-section and sputtering yield

NASA Astrophysics Data System (ADS)

Dartois, E.; Augé, B.; Boduch, P.; Brunetto, R.; Chabot, M.; Domaracka, A.; Ding, J. J.; Kamalou, O.; Lv, X. Y.; Rothard, H.; da Silveira, E. F.; Thomas, J. C.

2015-04-01

Context. Under cosmic irradiation, the interstellar water ice mantles evolve towards a compact amorphous state. Crystalline ice amorphisation was previously monitored mainly in the keV to hundreds of keV ion energies. Aims: We experimentally investigate heavy ion irradiation amorphisation of crystalline ice, at high energies closer to true cosmic rays, and explore the water-ice sputtering yield. Methods: We irradiated thin crystalline ice films with MeV to GeV swift ion beams, produced at the GANIL accelerator. The ice infrared spectral evolution as a function of fluence is monitored with in-situ infrared spectroscopy (induced amorphisation of the initial crystalline state into a compact amorphous phase). Results: The crystalline ice amorphisation cross-section is measured in the high electronic stopping-power range for different temperatures. At large fluence, the ice sputtering is measured on the infrared spectra, and the fitted sputtering-yield dependence, combined with previous measurements, is quadratic over three decades of electronic stopping power. Conclusions: The final state of cosmic ray irradiation for porous amorphous and crystalline ice, as monitored by infrared spectroscopy, is the same, but with a large difference in cross-section, hence in time scale in an astrophysical context. The cosmic ray water-ice sputtering rates compete with the UV photodesorption yields reported in the literature. The prevalence of direct cosmic ray sputtering over cosmic-ray induced photons photodesorption may be particularly true for ices strongly bonded to the ice mantles surfaces, such as hydrogen-bonded ice structures or more generally the so-called polar ices. Experiments performed at the Grand Accélérateur National d'Ions Lourds (GANIL) Caen, France. Part of this work has been financed by the French INSU-CNRS programme "Physique et Chimie du Milieu Interstellaire" (PCMI) and the ANR IGLIAS.

Paleomagnetic and Geochronologic Results of Latest Cretaceous Lava Flows From the Lhasa Terrane and Their Tectonic Implications

NASA Astrophysics Data System (ADS)

Ma, Yiming; Yang, Tianshui; Bian, Weiwei; Jin, Jingjie; Wang, Qiang; Zhang, Shihong; Wu, Huaichun; Li, Haiyan; Cao, Liwan; Yuan, Haifan; Ding, Jikai

2017-11-01

To position the Asian southern margin before the India-Asia collision, paleomagnetic and geochronologic studies were performed on the Dianzhong Formation lava flows from the Shiquanhe area of the westernmost Lhasa terrane (LT). Zircon U-Pb analyses dated the lava flows to 69.5 ± 2.5 Ma. The characteristic remanent magnetization directions contain antipodal polarities and pass fold tests, implying that they are primary magnetizations; this interpretation is supported by rock-magnetic analyses and petrographic observations. Forty-four site-mean directions were divided into 17 statistically independent direction groups. The group-mean direction after tilt correction is Ds = 43.3°, Is = 30.3°, k = 28.0, α95 = 6.9°. The corresponding paleopole at 47.8°N, 181.4°E (A95 = 6.4°) yields a paleolatitude of 16.6° ± 6.4°N for the Shiquanhe area of westernmost Tibet (32.34°N, 80.12°E). Consistent paleolatitudes for the southern margin of the LT calculated from the western and central part of the LT indicate that the leading edge of the LT was aligned relatively W-E. When compared with the reference pole at 70 Ma for Eurasia, this new paleopole suggests that crustal shortening between the Shiquanhe area and stable Asia was 1,500 ± 800 km. This is supported by the crustal shortening (600-1,000 km) absorbed by Cenozoic thrust and fold belts within this area, indicating that the magnitude of crustal shortening within Asia north of the India-Asia suture zone was similar in the central and western part of the plateau.

The latest results on colloid associated radionuclide migration from the CFM Project, Grimsel Test Site (GTS, Switzerland)

NASA Astrophysics Data System (ADS)

Schaefer, T.; Blechschmidt, I.; Bouby, M.; Buechner, S.; Brendlé, J.; Geckeis, H.; Kupcik, T.; Goetz, R.; Hauser, W.; Heck, S.; Huber, F. M.; Lagos, M.; Martin, A. J.

2013-12-01

The influence of colloidal/nano-scale phases on the radionuclide (RNs) solubility and migration behavior is still one of the uncertainties in repository safety assessment [1]. Within the Colloid Formation and Migration (CFM) project at the Grimsel Test Site (GTS Switzerland) a huge geo-technical effort was taken to isolate hydraulically a shear-zone from the artificially introduced hydraulic gradient due to the tunnel construction. The construction is a combination of polymer resin impregnation of the tunnel surface and a steel torus to seal the tunnel surface. Natural outflow points of the MI shear zone were localized prior to the construction and sealed by surface packers. This design gives the opportunity to adjust the flow velocity in the fracture. After optimization of the experimental setup and injection procedure through a number of conservative tracer tests a license was granted in January 2012 by the Swiss regulator (BAG) to perform the first radionuclide tracer test under these low-flow conditions. The injection cocktail of 2.25L volume consisted of 101.4 × 2.5 mg/L montmorillonite clay colloids, whereas 8.9 × 0.4mg/L were present as synthetic montmorillonite with structural incorporated Ni. For details on the structural characterization of the Ni-montmorillonite phyllosilicate, see [2]. Beside the colloids and the conservative tracer Amino-G (1646 × 8ppb) the radioisotopes Na-22, Ba-133, Cs-137, Th-232, Np-237, Pu-242 and Am-243 were injected. The trivalent and tetravalent actinides were quantitatively associated with the colloids present as well as a part of the Cs, whereas Np(V) and Na are not bentonite colloid bond. For on-site colloid analysis a mobile Laser- Induced Breakdown Detection (LIBD) system similar to the one used in the CRR experiments [3] was transferred to Grimsel and installed in-line at the 'Pinkel' outlet to directly monitor the mobile colloid fraction throughout the experiment. The conservative tracer Amino-G was recovered quantitatively and for the weakly sorbing tracers analyzed by γ-spectrometry recoveries for Na-22, Cs-137 and Ba-133 of 64%, 10% and 1%, respectively, were found. The clay colloid recovery determined by LIBD and HR-ICP-MS analyzing Al and Ni as structural components of the clay particles provided 48-52%. For the initial quantitatively colloid associated actinides Am(III) and Pu(IV) a recovery of 21-22% and 30-35%, respectively, could be determined. Np recovery is significantly reduced to ~4 %, which hints to a kinetic controlled Np(V) reduction. The data obtained so far clearly show the mobility of bentonite derived montmorillonite colloids under near-natural flow conditions in the MI shear zone of the Grimsel Test Site [4]. The experimental data will be discussed in detail in the presentation. [1] T. Schäfer, et al. Appl. Geochem., 27 (2012) 390-403. [2] Reinholdt, et al., Nanomaterials, 3 (2013) 48-69. [3] H. Geckeis, et al., Radiochim. Acta, 92 (2004) 765-774. [4] www.grimsel.com

Budget Cuts: Financial Aid Offices Face Budget Cuts and Increasing Workload. Quick Scan Survey Results

ERIC Educational Resources Information Center

National Association of Student Financial Aid Administrators (NJ1), 2010

2010-01-01

The majority of college financial aid offices have seen cuts to their operating budgets this year compared to the 2007-08 academic year when the recession began, according to the National Association of Student Financial Aid Administrator's latest QuickScan Survey. Sixty-two percent of financial aid offices reported operating budget cuts this year…

Latest developments in advanced network management and cross-sharing of next-generation flux stations

NASA Astrophysics Data System (ADS)

Burba, George; Johnson, Dave; Velgersdyk, Michael; Begashaw, Israel; Allyn, Douglas

2016-04-01

be merged into a single quality-control file (v) Multiple flux stations can be linked into an automated time-synchronized network (vi) Flux network managers, or PI's, can see all stations in real-time, including fluxes, supporting data, automated reports, and email alerts (vii) PI's can assign rights, allow or restrict access to stations and data: selected stations can be shared via rights-managed access internally or with external institutions (viii) Researchers without stations could form "virtual networks" for specific projects by collaborating with PIs from different actual networks This presentation provides detailed examples of FluxSuite currently utilized to manage two large flux networks in China (National Academy of Sciences and Agricultural Academy of Sciences), and smaller networks with stations in the USA, Germany, Ireland, Malaysia and other locations around the globe. Very latest 2016 developments and expanded functionality are also discussed.

List of Participants

NASA Astrophysics Data System (ADS)

2011-09-01

AbeTakashiUniversity of Tokyotabe@nt.phys.s.u-tokyo.ac.jp AmusiaMironRacah Institute of Physics, Jerusalemamusia@vms.huji.ac.il BaldoMarcelloINFN Cataniabaldo@ct.infn.it BansalManiePanjab University, Chandigarhbansalmanni@gmail.com BarrancoFranciscoUniversity of Sevillebarranco@us.es BertschGeorgeUniversity of Washington, Seattlebertsch@u.washington.edu BhagwatAmeeyaCBS Mumbaiameeya@kth.se BorderieBernardIPN Orsayborderie@ipno.in2p3.fr CarbonellJaumeLPSC Grenoblejaume.carbonell@lpsc.in2p3.fr CarlsonJoeLos Alamos National Laboratorycarlson@lanl.gov ColòGianlucaINFN - Università degli Studi di Milanocolo@mi.infn.it DanielewiczPawelNSCL, Michigan State Universitydanielewicz@nscl.msu.edu DescouvemontPierreUniversité Libre de Bruxellespdesc@ulb.ac.be Dohet-EralyJérémyUniversité Libre de Bruxellesjdoheter@ulb.ac.be DraayerJerryLouisiana State Universitydraayer@lsu.edu DufourMarianneIPHC, Université de Strasbourgmarianne.dufour@ires.in2p3.fr DuguetThomasCEA Saclaythomas.duguet@cea.fr DukelskyJorgeCSIC Madriddukelsky@iem.cfmac.csic.es EbranJean-PaulCEA-DAM, Arpajonebran@ipno.in2p3.fr FreerMartinUniversity of Birminghamm.freer@bham.ac.uk FujiiShinichiroUniversity of Tokyosfujii@cns.s.u-tokyo.ac.jp FunakiYasuroRIKEN Nishina Center, Wakofunaki@riken.jp GrassoMarcellaIPN Orsaygrasso@ipno.in2p3.fr HaginoKouichiTohoku Universityhagino@nucl.phys.tohoku.ac.jp HansenHubertUniversité Claude Bernard Lyon 1hansen@ipnl.in2p3.fr HolzmannMarkusLPMMC Grenoblemarkus@lptl.jussieu.fr HoriuchiHisashiRCNP, Osaka Universityhoriuchi@rcnp.osaka-u.ac.jp HoriuchiWataruGSI Darmstadtw.horiuchi@gsi.de HupinGuillaumeGANIL, Caenhupin@ganil.fr JinMengHuazhong Normal University, Wuhanjinm@iopp.ccnu.edu.cn KamimuraMasayasuRIKEN Nishina Center, Wakomkamimura@riken.jp Kanada-En'yoYoshikoKyoto Universityyenyo@ruby.scphys.kyoto-u.ac.jp KatoKiyoshiHokkaido University, Sapporokato@nucl.sci.hokudai.ac.jp KawabataTakahiroKyoto Universitykawabata@scphys.kyoto-u.ac.jp KhanEliasIPN Orsaykhan@ipno.in2p3.fr

Comment on "Most computational hydrology is not reproducible, so is it really science?" by Christopher Hutton et al.: Let hydrologists learn the latest computer science by working with Research Software Engineers (RSEs) and not reinvent the waterwheel ourselves

NASA Astrophysics Data System (ADS)

Hut, R. W.; van de Giesen, N. C.; Drost, N.

2017-05-01

The suggestions by Hutton et al. might not be enough to guarantee reproducible computational hydrology. Archiving software code and research data alone will not be enough. We add to the suggestion of Hutton et al. that hydrologists not only document their (computer) work, but that hydrologists use the latest best practices in designing research software, most notably the use of containers and open interfaces. To make sure hydrologists know of these best practices, we urge close collaboration with Research Software Engineers (RSEs).

Continuous atmospheric monitoring of the injected CO2 behavior over geological storage sites using flux stations: latest technologies and resources

NASA Astrophysics Data System (ADS)

Burba, George; Madsen, Rodney; Feese, Kristin

2014-05-01

quantify leakages from the subsurface, to improve storage efficiency, and for other storage characterizations [5-8]. In this presentation, the latest regulatory and methodological updates are provided regarding atmospheric monitoring of the injected CO2 behavior using flux stations. These include 2013 improvements in methodology, as well as the latest literature, including regulatory documents for using the method and step-by-step instructions on implementing it in the field. Updates also include 2013 development of a fully automated remote unattended flux station capable of processing data on-the-go to continuously output final CO2 emission rates in a similar manner as a standard weather station outputs weather parameters. References: [1] Burba G. Eddy Covariance Method for Scientific, Industrial, Agricultural and Regulatory Applications. LI-COR Biosciences; 2013. [2] International Energy Agency. Quantification techniques for CO2 leakage. IEA-GHG; 2012. [3] US Department of Energy. Best Practices for Monitoring, Verification, and Accounting of CO2 Stored in Deep Geologic Formations. US DOE; 2012. [4] Liu G. (Ed.). Greenhouse Gases: Capturing, Utilization and Reduction. Intech; 2012. [5] Finley R. et al. An Assessment of Geological Carbon Sequestration Options in the Illinois Basin - Phase III. DOE-MGSC; DE-FC26-05NT42588; 2012. [6] LI-COR Biosciences. Surface Monitoring for Geologic Carbon Sequestration. LI-COR, 980-11916, 2011. [7] Eggleston H., et al. (Eds). IPCC Guidelines for National Greenhouse Gas Inventories, IPCC NGGI P, WMO/UNEP; 2006-2011. [8] Burba G., Madsen R., Feese K. Eddy Covariance Method for CO2 Emission Measurements in CCUS Applications: Principles, Instrumentation and Software. Energy Procedia, 40C: 329-336; 2013.

Radiation effects in astrophysical ices

NASA Astrophysics Data System (ADS)

Boduch, Philippe; Dartois, Emmanuel; de Barros, Ana L. F.; da Silveira, Enio F.; Domaracka, Alicja; Lv, Xue-Yang; Palumbo, Maria Elisabetta; Pilling, Sergio; Rothard, Hermann; Seperuelo Duarte, Eduardo; Strazzulla, Giovanni

2015-07-01

The interaction of heavy ions with astrophysical ices was studied at different beamlines of GANIL by infrared absorption spectroscopy. This allowed simulating in the laboratory the physico-chemical modifications induced in icy objects in space, exposed to radiation fields such as the solar wind, magnetospheric particles and interstellar cosmic rays. We briefly discuss sputtering, destruction and formation of molecules, amorphization and compaction, implantation, and finally the formation of organic molecules. This latter topic is related to the question of the initial conditions for the emergence of life.

Preparation of osmium targets with carbon backing

NASA Astrophysics Data System (ADS)

Fremont, Georges; Ngono-Ravache, Yvette; Schmitt, Christelle; Stodel, Christelle

2018-05-01

For nuclear reaction studies, thin metallic osmium targets, either natural or isotopically enriched (Os-192) of 200-300 µg/cm2 thicknesses deposited on a thin carbon backing are required. A challenging method was successfully performed at GANIL involving firstly the preparation of an aqueous solution of osmium tetrachloride, then its electro-deposition onto a thick copper backing (100 µm); this process was followed by the evaporation of a thin carbon layer (≈40 µg/cm²) and finally the dissolution of the copper material.

Latest Pleistocene to Holocene Evolution of the Baie de Port au Prince, Haiti

NASA Astrophysics Data System (ADS)

Rios, J. K.; McHugh, C. M.; Seeber, L.; Blair, S.; Sorlien, C. C.

2012-12-01

The Baie de Port au Prince (BPP) is adjacent a restraining segment of the sinistral Caribbean-North America plate boundary and is therefore situated between converging high-relief thrust systems, the Massif Selle (Peninsula Range) to the south and the Chaine de Matheux (Hispaniola highlands) to the north. To evaluate neotectonic deformation, seismic hazards and sedimentation patterns for the BPP, six gravity cores were studied within the framework of chirp profiles collected from the R/V Endeavor in 2010. The cores were recovered from 76 m to 148 m of water depth sampling sediment from the carbonate platform that rims the BPP and from the slope. We studied the biostratigraphy (foraminifers, nannoplankton), geochemical elemental composition and physical properties of the sediment. An age model from the last glacial to the present (~20 ka BP) was derived from radiocarbon. Nannoplankton biostratigraphy provide constraints on the late Pleistocene. The BPP is 150 m maximum water depth and is rimmed by an ~30 m deep carbonate platform that has undergone dissolution. Terraces characterize the sub-bottom topography to the NE. This topography was covered by sediment during at least one relative sea-level cycle. Sediment progradation and mass-wasting on the northern and southern flanks of the BPP respectively, occurred during the latest Pleistocene low stand (~20 ka BP). Increased sedimentation from 0.2 mm/year to 0.8 mm/year occurred from 14.2 ka BP to 9.5 ka BP. This period also corresponds with a global rapid rate in sea-level rise from -94 m to -37 m. A basin wide acoustically transparent layer of sediment ~10 m thick covered the BPP. Mass-wasting, microfaulting, fluidization and turbidites caused by erosion triggered by pre-historic earthquakes possibly associated with EPG transform fault are found in the cores. One such deposit is possibly associated to the 2010 earthquake and another to an unconformable surface that separates early- from late-Holocene sediment on the

Latest Developments in Probiotics

NASA Astrophysics Data System (ADS)

Leroy, Frédéric; Falony, Gwen; Vuyst, Luc De

Probiotic foods are a group of health-promoting, so-called functional foods, with large commercial interest and growing market shares (Arvanitoyannis & van Houwelingen-Koukaliaroglou, 2005). In general, their health benefits are based on the presence of selected strains of lactic acid bacteria (LAB), that, when taken up in adequate amounts, confer a health benefit on the host. They are administered mostly through the consumption of fermented milks or yoghurts (Mercenier, Pavan, & Pot, 2003). In addition to their common use in the dairy industry, probiotic LAB strains may be used in other food products too, including fermented meats (Hammes & Hertel, 1998; Incze, 1998; Kröckel, 2006; Työppönen, Petäjä,& Mattila- Sandholm, 2003).

Latest advances in edema

NASA Technical Reports Server (NTRS)

Villavicencio, J. L.; Hargens, A. R.; Pikoulicz, E.

1996-01-01

Basic concepts in the physiopathology of edema are reviewed. The mechanisms of fluid exchange across the capillary endothelium are explained. Interstitial flow and lymph formation are examined. Clinical disorders of tissue and lymphatic transport, microcirculatory derangements in venous disorders, protein disorders, and lymphatic system disorders are explored. Techniques for investigational imaging of the lymphatic system are explained.

Latest in tire burning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Betzig, H.M.

1996-12-31

On September 26, Cris Lombardi and I presented a paper at the ARIPPA. The economic and environmental advantages available to CFB operators through the firing of tire-derived fuel (TDF) are discussed. The bottom line savings to the operation can be significant. It is believed that a regional scrap tire processing facility, capable of making properly-sized fuel, can be supported in Pennsylvania. An effort to develop such an operation is described. The technology for shredding and sizing TDF is well-proven. The proper equipment has been identified and reliable sources of scrap tires have been located. What is needed is to establishmore » a certain minimum annual TDF usage so that fuel user permit modification activity can begin. Data are presented on the production and use of TDF.« less

Alaska Volcano's Latest Eruption

Atmospheric Science Data Center

2017-06-06

... the Alaskan Volcano Observatory to issue a red alert for air travel in the area. Volcanic ash can cause major damage to aircraft engines, ...   On May 28, 2017, at approximately 2:23 p.m. local time, NASA's Terra satellite passed over Bogoslof, less than 10 minutes after ...

The Latest at Longview.

ERIC Educational Resources Information Center

Roark, Steven

2001-01-01

Discusses the solutions that administrators at Longview Community College in Kansas City, Missouri, used to deal with the classroom disruptions and groundwater collection caused during facility construction. (GR)

TASCA latest Image | CTIO

Science.gov Websites

Program PIA Program GO-FAAR Program Other Opportunities Tourism Visits to Tololo Astro tourism in Chile Tourism in Chile Information for travelers Visit Tololo Media Relations News Press Release Publications

Latest in Campus Transportation

ERIC Educational Resources Information Center

Molloy, Larry

1974-01-01

Innovations in handling bicycles, autos, and buses are appearing on campuses across the country. Computer-driven shuttle cars and monorails are on the way. Provides information sources for more data about ongoing, innovative campus transportation programs. (Author)

Latest Research: Genetic Links

MedlinePlus

... additional genetic risk factors. The network will also explore the relationship between a genetic disease and its ... surgery involves inserting a hollow needle into the space between the eye's retinal layers and transferring genetic ...

N/Z effect on reaction mechanisms cross sections in the 78 Kr +40 Ca and 86 Kr +48 Ca collisions at 10 AMeV

NASA Astrophysics Data System (ADS)

Gnoffo, B.; Pirrone, S.; Politi, G.; La Commara, M.; Wieleczko, J. P.; De Filippo, E.; Russotto, P.; Trimarchi, M.; Vigilante, M.; Ademard, G.; Auditore, L.; Beck, C.; Bercenau, I.; Bonnet, E.; Borderie, B.; Cardella, G.; Chibihi, A.; Colonna, M.; Dell'Aquila, D.; De Luca, S.; D'Onofrio, A.; Frankland, J. D.; Lanzalone, G.; Lautesse, P.; Lebhertz, D.; Le Neidre, N.; Lombardo, I.; Martorana, N. S.; Mazurek, K.; Norella, S.; Pagano, A.; Pagano, E. V.; Papa, M.; Piasecki, E.; Porto, F.; Quattrocchi, L.; Rizzo, F.; Spadaccini, G.; Trifirò, A.; Verde, G.

2017-06-01

Nuclear reactions between medium-mass nuclei at low energy are characterized by the competition between binary and evaporation process in the compound nucleus de-excitation. A study of the influence of the neutron richness of the entrance channel on the decay paths of the compound nuclei formed in the 78 Kr +40 Ca and 86 Kr +48 Ca at 10 MeV/A is presented. The experiment has been performed at Laboratori Nazionali del Sud by using the CHIMERA 4π multidetector for charged particles. The Kinematical characteristics of the two reactions support the conclusion of a production via long lived system. Besides the results relative to the n-poor system are compared to those obtained at GANIL, performed at 5.5 AMeV, in order to study the energy influence.

RMs1: qualification results of the rotary miniature Stirling cryocooler at Thales Cryogenics

NASA Astrophysics Data System (ADS)

Martin, Jean-Yves; Seguineau, Cédric; Van-Acker, Sébastien; Sacau, Mikel; Le Bordays, Julien; Etchanchu, Thierry; Vasse, Christophe; Abadie, Christian; Laplagne, Gilles; Benschop, Tonny

2017-05-01

The trend for miniaturized Integrated Dewar and Cooler Assemblies (IDCA) has been confirmed over the past few years with several mentions of a new generation of IR detector working at High Operating Temperature (HOT). This key technology enables the use of cryocooler with reduced needs of cryogenics power. As a consequence, miniaturized IDCA are the combination of a HOT IR detector coupled with a low-size, low-weight and low-power (SWaP) cryocooler. Thales Cryogenics has developed his own line of SWaP products. Qualification results on linear solution where shown last year. The current paper focuses on the latest results obtained on RMs1 prototypes, the new rotary SWaP cryocooler from Thales Cryogenics. Cryogenic performances and induced vibrations are presented. In a second part, progress is discussed on compactness and weight on one side, and on power consumption on the other side. It shows how the trade-off made between weight and power consumption could lead to an optimized solution at system level. At least, an update is made on the qualification status.

Latest Miocene transtensional rifting of northeast Isla Tiburón, eastern margin of the Gulf of California

NASA Astrophysics Data System (ADS)

Bennett, Scott E. K.; Oskin, Michael E.; Iriondo, Alexander

2017-11-01

Details about the timing and kinematics of rifting are crucial to understand the conditions that led to strain localization, continental rupture, and formation of the Gulf of California ocean basin. We integrate detailed geologic and structural mapping, basin analysis, and geochronology to characterize transtensional rifting on northeastern Isla Tiburón, a proximal onshore exposure of the rifted North America margin, adjacent to the axis of the Gulf of California. Slip on the Kunkaak normal fault tilted its hanging wall down-to-the-east 70° and formed the non-marine Tecomate basin, deposited across a 20° angular unconformity. From 7.1-6.4 Ma, the hanging wall tilted at 35 ± 5°/Myr, while non-marine sandstone and conglomerate accumulated at 1.4 ± 0.2 mm/yr. At least 1.8 ± 0.1 km of sediments and pyroclastic deposits accumulated in the Tecomate basin concurrent with clockwise vertical-axis block rotation and 2.8 km of total dip-slip motion on the Kunkaak fault. Linear extrapolation of tilting and sedimentation rates suggests that faulting and basin deposition initiated 7.6-7.4 Ma, but an older history involving initially slower rates is permissible. The Kunkaak fault and Tecomate basin are truncated by NW-striking, dextral-oblique structures, including the Yawassag fault, which accrued > 8 km of post-6.4 Ma dextral displacement. The Coastal Sonora fault zone on mainland Sonora, which accrued several tens of kilometers of late Miocene dextral offset, continues to the northwest, across northeastern Isla Tiburón and offshore into the Gulf of California. The establishment of rapid, latest Miocene transtension in the Coastal Sonora fault zone was synchronous with the 8-7 Ma onset of transform faulting and basin formation along the nascent Pacific-North America plate boundary throughout northwestern Mexico and southern California. Plate boundary strain localized into this Gulf of California shear zone, a narrow transtensional belt that subsequently hosted the

Diagnosing Early Ischemic Changes with the Latest-Generation Flat Detector CT: A Comparative Study with Multidetector CT.

PubMed

Maier, I L; Leyhe, J R; Tsogkas, I; Behme, D; Schregel, K; Knauth, M; Schnieder, M; Liman, J; Psychogios, M-N

2018-05-01

One-stop management of mechanical thrombectomy-eligible patients with large-vessel occlusion represents an innovative approach in acute stroke treatment. This approach reduces door-to-reperfusion times by omitting multidetector CT, using flat detector CT as pre-mechanical thrombectomy imaging. The purpose of this study was to compare the diagnostic performance of the latest-generation flat detector CT with multidetector CT. Prospectively derived data from patients with ischemic stroke with large-vessel occlusion and mechanical thrombectomy were analyzed in this monocentric study. All included patients underwent multidetector CT before referral to our comprehensive stroke center and flat detector CT in the angiography suite before mechanical thrombectomy. Diagnosis of early ischemic signs, quantified by the ASPECTS, was compared between modalities using cross tables, the Pearson correlation, and Bland-Altman plots. The predictive value of multidetector CT- and flat detector CT-derived ASPECTS for functional outcome was investigated using area under the receiver operating characteristic curve analysis. Of 25 patients, 24 (96%) had flat detector CT with sufficient diagnostic quality. Median multidetector CT and flat detector CT ASPECTSs were 7 (interquartile range, 5.5-9 and 4.25-8, respectively) with a mean period of 143.6 ± 49.5 minutes between both modalities. The overall sensitivity was 85.1% and specificity was 83.1% for flat detector CT ASPECTS compared with multidetector CT ASPECTS as the reference technique. Multidetector CT and flat detector CT ASPECTS were strongly correlated ( r = 0.849, P < .001) and moderately predicted functional outcome (area under the receiver operating characteristic curve, 0.738; P = .007 and .715; P = .069, respectively). Determination of ASPECTS on flat detector CT is feasible, showing no significant difference compared with multidetector CT ASPECTS and a similar predictive value for functional outcome. Our findings support the

A blast of gas in the latest Paleocene: simulating first-order effects of massive dissociation of oceanic methane hydrate.

PubMed

Dickens, G R; Castillo, M M; Walker, J C

1997-03-01

Carbonate and organic matter deposited during the latest Paleocene thermal maximum is characterized by a remarkable -2.5% excursion in delta 13C that occurred over approximately 10(4) yr and returned to near initial values in an exponential pattern over approximately 2 x 10(5) yr. It has been hypothesized that this excursion signifies transfer of 1.4 to 2.8 x 10(18) g of CH4 from oceanic hydrates to the combined ocean-atmosphere inorganic carbon reservoir. A scenario with 1.12 x 10(18) g of CH4 is numerically simulated here within the framework of the present-day global carbon cycle to test the plausibility of the hypothesis. We find that (1) the delta 13C of the deep ocean, shallow ocean, and atmosphere decreases by -2.3% over 10(4) yr and returns to initial values in an exponential pattern over approximately 2 x 10(5) yr; (2) the depth of the lysocline shoals by up to 400 m over 10(4) yr, and this rise is most pronounced in one ocean region; and (3) global surface temperature increases by approximately 2 degrees C over 10(4) yr and returns to initial values over approximately 2 x 10(6) yr. The first effect is quantitatively consistent with the geologic record; the latter two effects are qualitatively consistent with observations. Thus, significant CH4 release from oceanic hydrates is a plausible explanation for observed carbon cycle perturbations during the thermal maximum. This conclusion is of broad interest because the flux of CH4 invoked during the maximum is of similar magnitude to that released to the atmosphere from present-day anthropogenic CH4 sources.

A blast of gas in the latest Paleocene: simulating first-order effects of massive dissociation of oceanic methane hydrate

NASA Technical Reports Server (NTRS)

Dickens, G. R.; Castillo, M. M.; Walker, J. C.

1997-01-01

Carbonate and organic matter deposited during the latest Paleocene thermal maximum is characterized by a remarkable -2.5% excursion in delta 13C that occurred over approximately 10(4) yr and returned to near initial values in an exponential pattern over approximately 2 x 10(5) yr. It has been hypothesized that this excursion signifies transfer of 1.4 to 2.8 x 10(18) g of CH4 from oceanic hydrates to the combined ocean-atmosphere inorganic carbon reservoir. A scenario with 1.12 x 10(18) g of CH4 is numerically simulated here within the framework of the present-day global carbon cycle to test the plausibility of the hypothesis. We find that (1) the delta 13C of the deep ocean, shallow ocean, and atmosphere decreases by -2.3% over 10(4) yr and returns to initial values in an exponential pattern over approximately 2 x 10(5) yr; (2) the depth of the lysocline shoals by up to 400 m over 10(4) yr, and this rise is most pronounced in one ocean region; and (3) global surface temperature increases by approximately 2 degrees C over 10(4) yr and returns to initial values over approximately 2 x 10(6) yr. The first effect is quantitatively consistent with the geologic record; the latter two effects are qualitatively consistent with observations. Thus, significant CH4 release from oceanic hydrates is a plausible explanation for observed carbon cycle perturbations during the thermal maximum. This conclusion is of broad interest because the flux of CH4 invoked during the maximum is of similar magnitude to that released to the atmosphere from present-day anthropogenic CH4 sources.

Results of Long Term Life Tests of Large Scale Lithium-Ion Cells

NASA Astrophysics Data System (ADS)

Inoue, Takefumi; Imamura, Nobutaka; Miyanaga, Naozumi; Yoshida, Hiroaki; Komada, Kanemi

2008-09-01

High energy density Li-ion cells have been introduced to latest satellites and another space usage. We have started development of large scale Li-ion cells for space applications in 1997. The chemical design was fixed in 1999.It is very important to confirm life performance to apply satellite applications because it requires long mission life such as 15 years for GEO and 5 to 7 years for LEO. Therefore we started life test at various conditions. And the tests have reached 8 to 9 years in actual calendar time. Semi - accelerated GEO tests which gives both calendar and cycle loss have been reached 42 season that corresponds 21 years in orbit. The specific energy range is 120 - 130 Wh/kg at EOL. According to the test results, we have confirmed that our Li-ion cell meets general requirements for space application such as GEO and LEO with quite high specific energy.

New insights in geodynamics of wider Zagreb area: results of GPS measurements series 2009 on Zagreb Geodynamic Network

NASA Astrophysics Data System (ADS)

Pribičević, Boško; Medak, Damir; ĐApo, Almin

2010-05-01

The Geodynamic GPS-Network of the City of Zagreb represents the longest and the most intensive research effort in the field of geodynamics in Croatia. Since the establishment of the Network in 1997, several series of precise GPS measurements have been conducted on specially stabilized points of Geodynamical Network of City of Zagreb with purpose of investigation of tectonic movements and related seismic activity of the wider area of the City of Zagreb. The Network has been densified in 2005 in the most active region of northeastern Mount Medvednica. Since then, several GPS campaigns have been conducted including the last in summer 2009. The paper presents latest results of geodynamic movements of the network points.

Overview of the COMPASS results on the nucleon spin

NASA Astrophysics Data System (ADS)

Franco, Celso; COMPASS Collaboration

2016-04-01

The COMPASS experiment [COMPASS, P. Abbon et al., The COMPASS experiment at CERN, Nucl. Inst. Meth. A577, 455 (2007)] at CERN is one of the leading experiments studying the nucleon spin. These studies are being carried on since 2002, by measuring hadrons produced in deep inelastic scattering (DIS) of 160 GeV/c and 200 GeV/c polarised muons off different polarised targets (NH3 for polarised protons and 6LiD for polarised deuterons). One of the main goals is to determine how the total longitudinal spin projection of the nucleon, 1/2, is distributed among its constituents, quarks and gluons. We review here the recent results on the quark and gluon helicities obtained by COMPASS. The other major goal, whose fulfilment is needed for a complete understanding of the nucleon spin, is the determination of the transverse momentum dependent parton distributions (TMDs). Regarding this topic, the latest results on the Collins and Sivers asymmetries will be shown. The former is sensitive to the transverse spin structure of the nucleon, while the latter reflects the correlations between the quarks transverse momentum and the nucleon spin. This overview will conclude with a summary of the approved plans of COMPASS for the near future: the study of TMDs with a pioneering polarised Drell-Yan experiment and the measurement of generalised parton distributions (GPDs).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gales, S.

The exploration of unknown region of the nuclear mass chart, in particular, the neutron rich side, raised new and challenging physics issues in the understanding of nuclei far from stability. The physics of weakly bound systems, the appearance of shell quenching, the interface with astrophysical problems prompted the study of new generation of ''Rad ioactive Beam Facilities'' with high luminosity and the development of associated new experimental tools.GANIL presently offers unique opportunities in nuclear physics and many other fields. With the construction of SPIRAL2 over the next few years, GANIL is in a good position to retain its world-leading capabilitymore » even though it faces strong competition from new and upgraded ISOL and fragmentation facilities. As selected by the ESFRI committee, the next generation of ISOL facility in Europe is represented by the SPIRAL2 project to be built at GANIL (Caen, France). SPIRAL2 is based on a high power, CW, superconducting LINAC, delivering 5 mA of deuteron beams at 40 MeV (200 KW) directed on a C converter+ Uranium target and producing therefore more 10{sup 13} fissions/s. The expected radioactive beams intensities in the mass range from A = 60 to A = 140, will surpass by two order of magnitude any existing facilities in the world. These unstable atoms will be available at energies between few KeV/n to 15 MeV/n. The same driver will accelerate high intensity (100* A to 1 mA), heavier ions (Ar up to Xe) at maximum energy of 14 MeV/n.In applied areas SPIRAL2 is considered as a powerful variable energy neutron source. The Neutrons For Science collaboration (NFS) is proposing a physics program on fission induced by fast neutrons as well as fusion studies on materials.Under the 7FP program of European Union called 'Preparatory phase', the SPIRAL2 project has been granted a budget of about 4 MEuro to build up an international consortium around this new venture. Regarding the future physics program a call for Letter of

An Educational Program for Mental Health Nurses and Community Health Workers from Pacific Island Countries: Results from a Pilot Study

PubMed Central

Usher, Kim; Park, Tanya; Trueman, Scott; Redman-MacLaren, Michelle; Casella, Evan; Woods, Cindy

2014-01-01

Delivery of mental health care relies upon professionals with the latest evidence upon which to base their care. This research reports on a pre-test/post-test evaluation of a four-week education program delivered to Pacific Island participants (n = 18) to enhance knowledge, skills, and attitudes (KSAs). The education program used a combination of formal lectures, tutorials, clinical visits, simulations, and laboratory sessions. The measure used was the Nurse Self Report (NSR) questionnaire. Results indicate an education intervention can be an effective tool for improving the knowledge, skills, and attitudes of Pacific Island people who care for persons experiencing mental health problems. PMID:24766168

GERDA: Recent results and future plans

NASA Astrophysics Data System (ADS)

Lehnert, Björn

2014-04-01

The GERmanium Detector Array (GERDA) is an experiment designed to investigate the neutrinoless double beta decay (0 νββ) in 76Ge. An array of high purity germanium detectors isotopically enriched to 87% of 76Ge is operated within 64 m3 of liquid argon (LAr) at the Laboratori Nazionali del Gran Sasso (LNGS). The experiment aims to explore the 0 νββ half-life up to 1.4×1026 yr with a collected exposure of 100 kg yr separated into two physics phases. The data taking of Phase I started in November 2011 and finished in May 2013 with 21.6 kg yr of exposure and a background index (BI) of 2×10-2cts/(kg yr keV) around the Q-value of 2039 keV before pulse shape cuts. Phase II of the experiment is being prepared with additional 30 Broad Energy Germanium (BEGe) detectors and an instrumentation of the LAr, aiming at a BI reduction by a factor of 10 w.r. to Phase I. This paper will present the GERDA setup and the latest results of the experiment including a new measurement of the 2 νββ spectrum of 76Ge and the decomposition of the background spectrum. The 0 νββ analysis, finished in the meanwhile, will be briefly mentioned. Furthermore, the major improvements planned for Phase II will be discussed.

Transfer Paths of Research Results to the Practice: Observations From the Receiving End

NASA Astrophysics Data System (ADS)

Findikakis, A. N.

2005-12-01

A non-scientific poll of fellow practicing professionals suggests that there is a range of opinions regarding the effectiveness of different ways of becoming acquainted with and using the results of academic research in their practice. Journal articles remain the dominant path for transferring research results to the profession, even though accessing them is becoming more difficult with time. Driven primarily by cost considerations personal and corporate subscriptions seem to be on the decline. Libraries are one of the first victims of cost cutting measures in the industry. Even though the availability of journal articles in electronic form facilitates their availability, their prices are prohibitive. This is especially true during when a professional is searching for a solution to a problem and may have to review several papers on the subject. One colleague suggested that the professional organizations and other publishers of research articles could learn from the experience of the music industry, by lowering the cost of downloading individual papers to something like a dollar per article, recovering thus their production costs through the increase in the volume of purchased articles. The posting on the internet of special reports and dissertations by research institutions is viewed as very useful by those working in practice. The distribution through the internet of reports by federal organizations conducting or sponsoring research, such as the U.S. Geological Survey and the U.S. Environmental Protection Agency is greatly appreciated by the practicing professionals. The use of leading researchers as consultants provides a direct path for bringing research results to the practice, but it is limited to a small number of cases where bringing in a consultant can be justified. Short courses are viewed as an effective way of familiarizing professionals with the latest research findings on specific subjects. The notes distributed in such courses are considered

Collaboration of local government and experts responding to increase in environmental radiation level due to the nuclear disaster: focusing on their activities and latest radiological discussion.

PubMed

Iimoto, T; Nunokawa, J; Fujii, H; Takashima, R; Hashimoto, M; Fukuhara, T; Yajima, T; Matsuzawa, H; Kurosawa, K; Yanagawa, Y; Someya, S

2015-11-01

Activities were introduced in Kashiwa city in the Tokyo metropolitan area to correspond to the elevated environmental radiation level after the disaster of the Fukushima Daiichi nuclear power plant. These were based on a strong cooperation between local governments and experts. Ambient dose rate and radioactivity of foodstuff produced inside of the city have been monitored. Representative ambient dose rates around living environments have almost already become their original levels of the pre-accident because of the decontamination activity, natural washout and effective half-lives of radioactivity. The internal annual dose due to radioactive cesium under the policy of 'Local Production for Local Consumption' is estimated as extremely low comparing the variation range due to natural radioactivity. Systematic survey around a retention basin has been started. All of these latest monitoring data would be one of the core information for the policy making as well as a cost-benefit discussion and risk communication. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Latest generation of ASICs for photodetector readout

NASA Astrophysics Data System (ADS)

Seguin-Moreau, N.

2013-08-01

The OMEGA microelectronics group has designed a new generation of multichannel integrated circuits, the "ROC" family, in AustrianMicroSystem (AMS) SiGe 0.35 μm technology to read out signals from various families of photodetectors. The chip named MAROC (standing for Multi Anode ReadOut Chip) has been designed to read out MultiAnode Photomultipliers (MAPMT), Photomultiplier ARray In SiGe ReadOut Chip (PARISROC) to read out Photomultipliers (PMTs) and SiPM Integrated ReadOut Chip (SPIROC) to readout Silicon PhotoMultiplier (SiPM) detectors and which was the first ASIC to do so. The three of them fulfill the stringent requirements of the future photodetectors, in particular in terms of low noise, radiation hardness, large dynamic range, high density and high speed while keeping low power thanks to the SiGe technology. These multi-channel ASICs are real System on Chip (SoC) as they provide charge, time and photon-counting information which are digitized internally. Their complexity and versatility enable innovative frontier detectors and also cover spin off of these detectors in adjacent fields such as medical or material imaging as well as smart detectors. In this presentation, the three ASIC architectures and test results will be described to give a general panorama of the "ROC" chips.

Relative paleointensity (RPI) in the latest Pleistocene (10-45 ka) and implications for the "mystery interval" in atmospheric radiocarbon production at 17 ka.

NASA Astrophysics Data System (ADS)

Channell, J. E. T.; Hodell, D. A.

2017-12-01

Relative paleointensity (RPI) proxies have been used to improve the resolution of Quaternary stratigraphies, and have been matched to oxygen isotope stratigraphies over the last 2 Myrs. The archeomagnetic archive has been important for the Holocene RPI record, and the older Quaternary record has come largely from ODP/IODP and MD (Marion Dufresne - Calypso) marine cores. Beyond the range of archeomagnetic data, published RPI stacks have poor consistency in the 10-30 ka (latest Pleistocene) interval, possibly due to poor quality of ODP/IODP and MD cores in the upper few meters of the sedimentary sections. We report RPI data from a suite of conventional piston cores and Kasten cores from the SW Iberian margin collected during cruise JC089 of the RSS James Cook in August 2013. The age models were acquired by correlation of Ca/Ti XRF core-scanning data to L* reflectance from the Cariaco Basin that is tied to the Greenland ice-core chronology. Mean sedimentation rates are in the 10-20 cm/kyr range. The Holocene RPI record from these marine cores can be broadly correlated to the archeomagnetic RPI compilations. The preceding RPI data are characterized by a short-lived minimum at 13-15 ka, a high in RPI at 17-20 ka, preceded by a discontinuous RPI decrease to 40 ka at the time of the well-documented Laschamp geomagnetic excursion. A stack of 12 RPI records from the SW Iberian margin for the 0-45 ka interval are compared with 11 records from elsewhere, including marine and lake records from the Pacific and South Atlantic realms, chosen on the basis of mean sedimentation rates (>20 cm/kyr) and superior age models. The resulting stacks are very different to previously published RPI stacks, particularly for the 10-30 ka interval, and imply a global (dipole-field) high at 17-20 ka that has implications for the 190 ‰ drop in atmospheric 14C during the so-called "mystery interval" (17.5-14.5 ka).

Latest Advancement In Airborne Relative Gravity Instrumentation.

NASA Astrophysics Data System (ADS)

Brady, N.

2011-12-01

Airborne gravity surveying has been performed with widely varying degrees of success since early experimentation with the Lacoste and Romberg dynamic meter in the 1950s. There are a number of different survey systems currently in operation including relative gravity meters and gradiometers. Airborne gravity is ideally suited to rapid, wide coverage surveying and is not significantly more expensive in more remote and inhospitable terrain which makes airborne measurements one of the few viable options available for cost effective exploration. As improved instrumentation has become available, scientific applications have also been able to take advantage for use in determining sub surface geologic structures, for example under ice sheets in Antarctica, and more recently direct measurement of the geoid to improve the vertical datum in the United States. In 2004, Lacoste and Romberg (now Micro-g Lacoste) decided to build on their success with the newly developed AirSea II dynamic meter and use that system as the basis for a dedicated airborne gravity instrument. Advances in electronics, timing and positioning technology created the opportunity to refine both the hardware and software, and to develop a truly turnkey system that would work well for users with little or no airborne gravity experience as well as those with more extensive experience. The resulting Turnkey Airborne Gravity System (TAGS) was successfully introduced in 2007 and has since been flown in applications from oil, gas and mineral exploration surveys to regional gravity mapping and geoid mapping. The system has been mounted in a variety of airborne platforms including depending on the application of interest. The development experience with the TAGS enabled Micro-g Lacoste to embark on a new project in 2010 to completely redesign the mechanical and electronic components of the system rather than continuing incremental upgrades. Building on the capabilities of the original TAGS, the objectives for the

WFIRST Coronagraph Technology Development Testbeds: Status and Recent Testbed Results

NASA Astrophysics Data System (ADS)

Shi, Fang; An, Xin; Balasubramanian, Kunjithapatham; cady, eric; Gordon, Brian; Greer, Frank; Kasdin, N. Jeremy; Kern, Brian; Lam, Raymond; Marx, David; Moody, Dwight; Patterson, Keith; Poberezhskiy, Ilya; mejia prada, camilo; Gersh-Range, Jessica; Eldorado Riggs, A. J.; Seo, Byoung-Joon; Shields, Joel; Sidick, Erkin; Tang, Hong; Trauger, John Terry; Truong, Tuan; White, Victor; Wilson, Daniel; Zhou, Hanying; JPL WFIRST Testbed Team, Princeton University

2018-01-01

As a part of technology development for the WFIRST coronagraph instrument (CGI), dedicated testbeds are built and commissioned at JPL. The coronagraph technology development testbeds include the Occulting Mask Coronagraph (OMC) testbed, the Shaped Pupil Coronagraph/Integral Field Spectrograph (SPC/IFS) testbed, and the Vacuum Surface Gauge (VSG) testbed. With its configuration similar to the WFIRST flight coronagraph instrument the OMC testbed consists of two coronagraph modes, Shaped Pupil Coronagraph (SPC) and Hybrid Lyot Coronagraph (HLC), a low order wavefront sensor (LOWFS), and an optical telescope assembly (OTA) simulator which can generate realistic LoS drift and jitter as well as low order wavefront error that would be induced by the WFIRST telescope’s vibration and thermal changes. The SPC/IFS testbed is a dedicated testbed to test the IFS working with a Shaped Pupil Coronagraph while the VSG testbed is for measuring and calibrating the deformable mirrors, a key component used for WFIRST CGI's wavefront control. In this poster, we will describe the testbed functions and status as well as the highlight of the latest testbed results from OMC, SPC/IFS and VSG testbeds.

Latest Paleocene benthic extinction event on the southern Tethyan shelf (Egypt): Foraminiferal stable isotopic (δ13C, δ18O) records

NASA Astrophysics Data System (ADS)

Schmitz, B.; Speijer, R. P.; Aubry, M.-P.

1996-04-01

The dramatic global extinction of 35% 50% of benthic foraminifera species in the deep sea in the latest Paleocene and associated negative excursions in δ13C and δ18O may be related to spreading of warm, saline bottom water from subtropical Tethyan shallow regions over the sea floor worldwide. Our study of neritic sections in Egypt shows that in the southern shallow Tethys, a prominent long-term change in bottom-water chemistry, sedimentation, and benthic foraminifera fauna was initiated at the time when the deep-sea benthic extinction event (BEE) took place. Bottom-water δ13C values on the Tethyan shelf show a sudden 3.0‰ negative shift at this event; however, contrary to the deep sea, in which the δ13C excursion was of short duration, Tethyan δ13C values did not fully return to preboundary values, but remained depressed by ˜1.5‰ for at least 1 m.y. The δ13C values at the Egyptian shelf during the BEE are much lower than would be expected if this was a source region for global deep water. The δ18O values indicate no significant change in bottom-water salinity or temperature at the BEE. The long-lasting environmental changes that began on the Egyptian shelf at the BEE may be related to, for example, gateway reorganization along the Tethyan seaway. Paleogeographic changes possibly also triggered a change in the loci of global deep-water formation; however, these loci must be sought in another part of the Tethys.

The ESA scientific exploitation element results and outlook

NASA Astrophysics Data System (ADS)

Desnos, Yves-louis; Regner, Peter; Delwart, Steven; Benveniste, Jerome; Engdahl, Marcus; Donlon, Craig; Mathieu, Pierre-Philippe; Fernandez, Diego; Gascon, Ferran; Zehner, Claus; Davidson, Malcolm; Goryl, Philippe; Koetz, Benjamin; Pinnock, Simon

2017-04-01

The Scientific Exploitation of Operational Missions (SEOM) element of ESA's fourth Earth Observation Envelope Programme (EOEP4) prime objective is to federate, support and expand the international research community built up over the last 25 years exploiting ESA's EO missions. SEOM enables the science community to address new scientific research areas that are opened by the free and open access to data from operational EO missions. Based on community-wide recommendations, gathered through a series of international thematic workshops and scientific user consultation meetings, key research studies have been launched over the last years to further exploit data from the Sentinels (http://seom.esa.int/). During 2016 several Science users consultation workshops have been organized, new results from scientific studies have been published and open-source multi-mission scientific toolboxes have been distributed (SNAP 80000 users from 190 countries). In addition the first ESA Massive Open Online Courses on Climate from space have been deployed (20000 participants) and the second EO Open Science conference was organized at ESA in September 2016 bringing together young EO scientists and data scientists. The new EOEP5 Exploitation element approved in 2016 and starting in 2017 is taking stock of all precursor activities in EO Open Science and Innovation and in particular a workplan for ESA scientific exploitation activities has been presented to Member States taking full benefit of the latest information and communication technology. The results and highlights from current scientific exploitation activities will be presented and an outlook on the upcoming activities under the new EOEP5 exploitation element will be given.

Lifetimes of excited states in triaxially deformed 107Tc and 109,111,113Rh

NASA Astrophysics Data System (ADS)

Hagen, T. W.; Görgen, A.; Korten, W.; Grente, L.; Salsac, M.-D.; Farget, F.; Braunroth, T.; Bruyneel, B.; Celikovic, I.; Clément, E.; de France, G.; Delaune, O.; Dewald, A.; Dijon, A.; Hackstein, M.; Jacquot, B.; Litzinger, J.; Ljungvall, J.; Louchart, C.; Michelagnoli, C.; Napoli, D. R.; Recchia, F.; Rother, W.; Sahin, E.; Siem, S.; Sulignano, B.; Theisen, Ch.; Valiente-Dobon, J. J.

2018-03-01

Lifetimes of excited states in 107Tc, 109Rh, 111Rh, and 113Rh were measured at GANIL using the Recoil-Distance Doppler Shift method. The neutron-rich nuclei were produced in fission reactions in inverse kinematics with a 238U beam impinging on a 9Be target. Fission fragments were identified event-by-event in the ray-tracing spectrometer VAMOS++ and correlated with prompt γ rays observed around the target position with the EXOGAM Ge detector array. Several lifetimes were obtained for states in the positive-parity yrast bands in the four nuclei and compared to triaxial particle-rotor calculations. The results clarify the configuration for the strongest positive-parity band in 107Tc and suggest a gradual increase of triaxial deformation with atomic number Z, reaching almost maximum triaxiality for the neutron-rich Rh nuclei.

Cocaine phenomenology study: results of a third in a series of field trials

NASA Astrophysics Data System (ADS)

Su, Chih-Wu; Rigdon, Stephen W.; Ricard, Steve; Hoglund, David E.; Drolet, Gerry; Neudorfl, Pavel; Hupe, Michael; Kunz, Terry D.; Ulvick, Sydney J.; Demirgian, Jack C.; Shier, Patrick; Wingo, Jeff J.

1997-01-01

To form an understanding of the environment in which non- intrusive detection and inspection technologies are required to operate, the Narcotic Detection Technology assessment Team has undertaken a series of field studies. These field studies have focused on the phenomenology, fate and behavior of narcotic residue in real world environments. The overall goal of the tests is to give Law Enforcement officers the ability to accurately differentiate between individuals involved in the smuggling process and individuals innocently contaminated with narcotics. The latest filed study in this series was conducted in Miami, FL in February 1996. The field study comprised several individual tests. The first was a contamination and transfer study which focuses on human contamination resulting from contact with actual kilos of cocaine and the mechanism by which this contamination transfers to surrounding objects, if at all. The second was a secondary contamination study which focused on determining the conditions under which cocaine contamination transfers from objects touched by individuals who handled narcotics to innocent passerbys. The third was a persistence study which focused on the persistence of cocaine contamination on people under a variety of conditions. An overview of the tests and their preliminary results will be discussed.

Beta decay of exotic TZ = -1, -2 nuclei: the interesting case of 56Zn

NASA Astrophysics Data System (ADS)

Orrigo, S. E. A.; Rubio, B.; Fujita, Y.; Blank, B.; Gelletly, W.; Agramunt, J.; Algora, A.; Ascher, P.; Bilgier, B.; Cáceres, L.; Cakirli, R. B.; Fujita, H.; Ganioğlu, E.; Gerbaux, M.; Giovinazzo, J.; Grévy, S.; Kamalou, O.; Kozer, H. C.; Kucuk, L.; Kurtukian-Nieto, T.; Molina, F.; Popescu, L.; Rogers, A. M.; Susoy, G.; Stodel, C.; Suzuki, T.; Tamii, A.; Thomas, J. C.

2014-03-01

The β decay properties of the Tz = -2, 56Zn isotope and other proton-rich nuclei in the fp-shell have been investigated in an experiment performed at GANIL. The ions were produced in fragmentation reactions and implanted in a double-sided silicon strip detector surrounded by Ge EXOGAM clovers. Preliminary results for 56Zn are presented .The 56Zn decay proceeds mainly by β delayed proton emission, but β delayed gamma rays were also detected. Moreover, the exotic β delayed gamma-proton decay was observed for the first time. The 56Zn half-life and the energy levels populated in the 56Cu daughter have been determined. Knowledge of the gamma de-excitation of the mirror states in 56Co and the comparison with the results of the mirror charge exchange process, the 56Fe(3He,t) reaction (where 56Fe has Tz = +2), were important in the interpretation of the 56Zn decay data. The absolute Fermi and Gamow-Teller strengths have been deduced.

Meteorite heat capacities: Results to date

NASA Astrophysics Data System (ADS)

Consolmagno, G.; Macke, R.; Britt, D.

2014-07-01

. We will present an updated list of our results, incorporating our latest corrections for a variety of small but measurable systematic errors, and new results for meteorites and meteorite types not previously measured or reported.

Pulsars Probe the Low-Frequency Gravitational Sky: Pulsar Timing Arrays Basics and Recent Results

NASA Astrophysics Data System (ADS)

Tiburzi, Caterina

2018-03-01

Pulsar Timing Array experiments exploit the clock-like behaviour of an array of millisecond pulsars, with the goal of detecting low-frequency gravitational waves. Pulsar Timing Array experiments have been in operation over the last decade, led by groups in Europe, Australia, and North America. These experiments use the most sensitive radio telescopes in the world, extremely precise pulsar timing models and sophisticated detection algorithms to increase the sensitivity of Pulsar Timing Arrays. No detection of gravitational waves has been made to date with this technique, but Pulsar Timing Array upper limits already contributed to rule out some models of galaxy formation. Moreover, a new generation of radio telescopes, such as the Five hundred metre Aperture Spherical Telescope and, in particular, the Square Kilometre Array, will offer a significant improvement to the Pulsar Timing Array sensitivity. In this article, we review the basic concepts of Pulsar Timing Array experiments, and discuss the latest results from the established Pulsar Timing Array collaborations.

Usefulness of In Vivo and In Vitro Diagnostic Tests in the Diagnosis of Hypersensitivity Reactions to Quinolones and in the Evaluation of Cross-Reactivity: A Comprehensive Study Including the Latest Quinolone Gemifloxacin

PubMed Central

Gelincik, Asli; Akdeniz, Nilgun; Aktas-Cetin, Esin; Olgac, Muge; Unal, Derya; Ertek, Belkis; Coskun, Raif; Colakoğlu, Bahattin; Deniz, Gunnur; Buyukozturk, Suna

2017-01-01

Purpose Reports evaluating diagnosis and cross reactivity of quinolone hypersensitivity have revealed contradictory results. Furthermore, there are no reports investigating the cross-reactivity between gemifloxacin (GFX) and the others. We aimed to detect the usefulness of diagnostic tests of hypersensitivity reactions to quinolones and to evaluate the cross reactivity between different quinolones including the latest quinolone GFX. Methods We studied 54 patients (mean age 42.31±10.39 years; 47 female) with 57 hypersensitivity reactions due to different quinolones and 10 nonatopic quinolone tolerable control subjects. A detailed clinical history, skin test (ST), and single-blind placebo-controlled drug provocation test (SBPCDPT), as well as basophil activation test (BAT) and lymphocyte transformation test (LTT) were performed with the culprit and alternative quinolones including ciprofloxacin (CFX), moxifloxacin (MFX), levofloxacin (LFX), ofloxacin (OFX), and GFX. Results The majority (75.9%) of the patients reported immediate type reactions to various quinolones. The most common culprit drug was CFX (52.6%) and the most common reaction type was urticaria (26.3%). A quarter of the patients (24.1%) reacted to SBPCDPTs, although their STs were negative; while false ST positivity was 3.5% and ST/SBPCDPTs concordance was only 1.8%. Both BAT and LTT were not found useful in quinolone hypersensitivity. Cross-reactivity was primarily observed between LFX and OFX (50.0%), whereas it was the least between MFX and the others, and in GFX hypersensitive patients the degree of cross-reactivity to the other quinolones was 16.7%. Conclusions These results suggest that STs, BAT, and LTT are not supportive in the diagnosis of a hypersensitivity reaction to quinolone as well as in the prediction of cross-reactivity. Drug provocation tests (DPTs) are necessary to identify both culprit and alternative quinolones. PMID:28497922

Latest Holocene Mapping of Tsunamigenically- and Seismogenically-Influenced Beach, Dune and Fluvial Landforms at Tolowa Dunes State Park, Northwestern California

NASA Astrophysics Data System (ADS)

Vaughan, P. R.

2015-12-01

Beach, dune, fluvial, and marine terrace deposits comprise a 16 kilometer (km) coastal strip immediately south of the Smith River at Tolowa Dunes State Park (TDSP), ~ 3.5 km north-northwest from downtown Crescent City, California. The park has numerous Native American sites that are vulnerable to sea level rise and coastal erosion, part of which may be influenced by Cascadia interseismic deformation. Efforts at removal of exotic beach grass (Ammophila arenaria) that stabilizes most of the dune complex have begun; vegetation removal will remobilize the dunes and could obscure and also expose near surficial geologic features. Using a LiDAR base to capture extant data and give context to future resource protection projects, I surficially mapped the dunes and provisionally interpreted, tsunamigenically-derived cobbles (which are more than five feet thick in one road cut exposure) that extensively mantle the deflation plain in the lee of the foredune. Natural, test pit and auger exposures helped characterize fluvial and marsh deposits in the southern bank and floodplain of the Smith River. Optically stimulated luminescence and/or radiocarbon dates constrain the ages for cobble deposits and dunes throughout the park, and liquefaction features exposed in the southern bank of the Smith River. In combination with estimated rates of dune formation and migration at TDSP since the A.D. 1700 Cascadia earthquake, the ages for seismogenically-sourced sediment associated with dune ridges and cobble deposits are tentatively correlated with the ages of latest Holocene Cascadia triggered turbidites dated by Goldfinger et al. (2012) on the Smith River platform. The mapping also helped identify a marine terrace sequence on the southern limb of the northwest-trending Lake Earl Syncline that bifurcates the park, and suggests projection of the northwest-trending Cemetery Scarp, part of the Point St. George fault complex (Polenz and Kelsey 1999), through the southern part of the park.

Species Boundaries and Interrelationships of Solanum Sect. Petota (Wild and Cultivated Potatoes) are Drastically Altered as a Result of PBI-Funded Research

USDA-ARS?s Scientific Manuscript database

In 1990, the latest comprehensive taxonomic monograph of Solanum section Petota Dumort, recognized 232 species partitioned into 21 series. PBI-sponsored research has drastically altered knowledge of their species boundaries and interrelationships. The series contains diploids (2n = 2x = 24), tetrapl...

Species Boundaries and Interrelationships of Solanum Sect. Petota (Wild and Cultivated Potatoes) are Drastically Altered as a Result of PBI-Funded Research

USDA-ARS?s Scientific Manuscript database

In 1990, the latest comprehensive taxonomic monograph of Solanum section Petota Dumort recognized 232 species partitioned into 21 series. PBI-sponsored research has drastically altered knowledge of their species boundaries and interrelationships. The series contains diploids (2n = 2x = 24), tetraplo...

Latest developments in resonantly diode-pumped Er:YAG lasers

NASA Astrophysics Data System (ADS)

Kudryashov, Igor; Garbuzov, Dmitri; Dubinskii, Mark

2007-04-01

Significant performance improvement of the Er(0.5%):YAG diode pumped solid state laser (DPSSL) has been achieved by pump diode spectral narrowing via implementation of an external volumetric Bragg grating (VBG). Without spectral narrowing, with a pump path length of 15 mm, only 37% of 1532 nm pump was absorbed. After the VBG spectral narrowing, the absorption of the pumping radiation increased to 62 - 70%. As a result, the incident power threshold was reduced by a factor of 2.5, and the efficiency increased by a factor of 1.7, resulting in a slope efficiency of ~23 - 30%. A maximum of 51 W of CW power was obtained versus 31 W without the pump spectrum narrowing. More than 180 mJ QCW pulse output energy was obtained in a stable-unstable resonator configuration with a beam quality of M2 = 1.3 in the stable direction and M2 = 1.1 in the unstable direction. The measured slope efficiency was 0.138 J/J with a threshold energy of 0.91 J.

Preliminary Results on Lunar Interior Properties from the GRAIL Mission

NASA Technical Reports Server (NTRS)

Williams, James G.; Konopliv, Alexander S.; Asmar, Sami W.; Lemoine, H. Jay; Melosh, H. Jay; Neumann, Gregory A.; Phillips, Roger J.; Smith, David E.; Solomon, Sean C.; Watkins, Michael M.;

Conceptual Approach for Precise Relative Positioning with Miniaturized GPS Loggers and Experimental Results

DTIC Science & Technology

2010-03-01

readily met by standard single frequency GPS receiver modules as used in car navigation systems or latest generation cell phones. However...different strategies can now be applied as shown in Figure 5. btbξ SPP bξδ iξ itbiβ (a) Over-all solution btbξ SPP bξδ iξ it nn ,1−β 1− nt1 −nξ nξ nt (b... cells . The mass of the complete logging unit did not exceed 100 g. Some receivers additionally featured 3 axis MEMS accelerometers. Mounting on the

The Impact of the Latest Danian Event on Planktic Foraminiferal Faunas at ODP Site 1210 (Shatsky Rise, Pacific Ocean).

PubMed

Jehle, Sofie; Bornemann, André; Deprez, Arne; Speijer, Robert P

2015-01-01

The marine ecosystem has been severely disturbed by several transient paleoenvironmental events (<200 kyr duration) during the early Paleogene, of which the Paleocene-Eocene Thermal Maximum (PETM, ~56 Ma) was the most prominent. Over the last decade a number of similar events of Paleocene and Eocene age have been discovered. However, relatively little attention has been paid to pre-PETM events, such as the "Latest Danian Event" ("LDE", ~62.18 Ma), specifically from an open ocean perspective. Here we present new foraminiferal isotope (δ13C, δ18O) and faunal data from Ocean Drilling Program (ODP) Site 1210 at Shatsky Rise (Pacific Ocean) in order to reconstruct the prevailing paleoceanographic conditions. The studied five-meter-thick succession covers ~900 kyr and includes the 200-kyr-lasting LDE. All groups surface dwelling, subsurface dwelling and benthic foraminifera show a negative δ13C excursion of >0.6‰, similar in magnitude to the one previously reported from neighboring Site 1209 for benthic foraminifera. δ18O-inferred warming by 1.6 to 2.8°C (0.4-0.7‰ δ18O measured on benthic and planktic foraminiferal tests) of the entire water column accompanies the negative δ13C excursion. A well stratified upper ocean directly before and during the LDE is proposed based on the stable isotope gradients between surface and subsurface dwellers. The gradient is less well developed, but still enhanced after the event. Isotope data are supplemented by comprehensive planktic foraminiferal faunal analyses revealing a dominance of Morozovella species together with Parasubbotina species. Subsurface-dwelling Parasubbotina shows high abundances during the LDE tracing changes in the strength of the isotope gradients and, thus, may indicate optimal living conditions within a well stratified surface ocean for this taxon. In addition, distinct faunal changes are reported like the disappearance of Praemurica species right at the base of the LDE and the continuous replacement

The Impact of the Latest Danian Event on Planktic Foraminiferal Faunas at ODP Site 1210 (Shatsky Rise, Pacific Ocean)

PubMed Central

Jehle, Sofie; Bornemann, André; Deprez, Arne; Speijer, Robert P.

2015-01-01

The marine ecosystem has been severely disturbed by several transient paleoenvironmental events (<200 kyr duration) during the early Paleogene, of which the Paleocene-Eocene Thermal Maximum (PETM, ~56 Ma) was the most prominent. Over the last decade a number of similar events of Paleocene and Eocene age have been discovered. However, relatively little attention has been paid to pre-PETM events, such as the “Latest Danian Event” ("LDE", ~62.18 Ma), specifically from an open ocean perspective. Here we present new foraminiferal isotope (δ13C, δ18O) and faunal data from Ocean Drilling Program (ODP) Site 1210 at Shatsky Rise (Pacific Ocean) in order to reconstruct the prevailing paleoceanographic conditions. The studied five-meter-thick succession covers ~900 kyr and includes the 200-kyr-lasting LDE. All groups surface dwelling, subsurface dwelling and benthic foraminifera show a negative δ13C excursion of >0.6‰, similar in magnitude to the one previously reported from neighboring Site 1209 for benthic foraminifera. δ18O-inferred warming by 1.6 to 2.8°C (0.4–0.7‰ δ18O measured on benthic and planktic foraminiferal tests) of the entire water column accompanies the negative δ13C excursion. A well stratified upper ocean directly before and during the LDE is proposed based on the stable isotope gradients between surface and subsurface dwellers. The gradient is less well developed, but still enhanced after the event. Isotope data are supplemented by comprehensive planktic foraminiferal faunal analyses revealing a dominance of Morozovella species together with Parasubbotina species. Subsurface-dwelling Parasubbotina shows high abundances during the LDE tracing changes in the strength of the isotope gradients and, thus, may indicate optimal living conditions within a well stratified surface ocean for this taxon. In addition, distinct faunal changes are reported like the disappearance of Praemurica species right at the base of the LDE and the continuous

A geomorphologist's dream come true: synoptic high resolution river bathymetry with the latest generation of airborne dual wavelength lidar

NASA Astrophysics Data System (ADS)

Lague, Dimitri; Launeau, Patrick; Michon, Cyril; Gouraud, Emmanuel; Juge, Cyril; Gentile, William; Hubert-Moy, Laurence; Crave, Alain

2016-04-01

Airborne, terrestrial lidar and Structure From Motion have dramatically changed our approach of geomorphology, from low density/precision data, to a wealth of data with a precision adequate to actually measure topographic change across multiple scales, and its relation to vegetation. Yet, an important limitation in the context of fluvial geomorphology has been the inability of these techniques to penetrate water due to the use of NIR laser wavelengths or to the complexity of accounting for water refraction in SFM. Coastal bathymetric systems using a green lidar can penetrate clear water up to 50 m but have a resolution too coarse and deployment costs that are prohibitive for fluvial research and management. After early prototypes of narrow aperture green lidar (e.g., EEARL NASA), major lidar manufacturer are now releasing dual wavelength laser system that offer water penetration consistent with shallow fluvial bathymetry at very high resolution (> 10 pts/m²) and deployment costs that makes the technology, finally accessible. This offers unique opportunities to obtain synoptic high resolution, high precision data for academic research as well as for fluvial environment management (flood risk mapping, navigability,…). In this presentation, we report on the deployment of the latest generation Teledyne-Optech Titan dual-wavelength lidar (1064 nm + 532 nm) owned by the University of Nantes and Rennes. The instrument has been deployed over several fluvial and lacustrine environments in France. We present results and recommendation on how to optimize the bathymetric cover as a function of aerial and aquatic vegetation cover and the hydrology regime of the river. In the surveyed rivers, the penetration depth varies from 0.5 to 4 m with discrete echoes (i.e., onboard detection), heavily impacted by water clarity and bottom reflectance. Simple post-processing of the full waveform record allows to recover an additional 20 % depth. As for other lidar techniques, the main

Subduction erosion and implication for evolution model of the Yap trench: new evidence from the latest geophysical survey

NASA Astrophysics Data System (ADS)

Zhang, Z.; Dong, D.; Bai, Y.; Zhang, G.

2017-12-01

The subduction of oceanic plateau, including the ridge and seamount, with buoyant feature will lead to the occurrence of subduction erosion. Yap Trench is a unique structure related to the Caroline Ridge subduction, but with lower research degree. Previous studies lacked the investigation of crustal structure and subduction erosion model based on integrated geophysical data in Yap Trench. In 2015, Institute of Oceanology, Chinese Academy of Sciences acquired swath bathymetric, multi-channel seismic and gravity data by research vessel "Kexue" in the Yap Trench and its adjacent area, providing the chance to further explore this subduction system. For this research, we mainly used the latest data to analyze the topography and crustal structure in Yap subduction system, which is significant for the construction of subduction erosion model. We reveal that, (1) The mean value of arc-ward slope is 8° according with bathymetric slope features in erosive margins(>3°). The increasing trend to dip angles in arc-ward slope shows the control of subducting plate with different elevation from north to south; (2) The horst and graben structures and different scales of seamounts display the rough features in the subducting plate, facilitating the overlying Yap Arc erosion. In the front of the Yap Arc, collision scars identified on the bathymetric map indicates the seamount subducting; (3) The horst and graben structures, with thinner crust of 2-4 km thick, in subducting plate, possibly eroded the Yap Arc basement and made it thinner during subduction. The subducted seamounts with high topography underplated the Yap Arc, which uplifted and thickened the overlying plate crust. Therefore, it is suggested that. subduction erosion model is varied in Yap subduction sysytem which is affected by topography and crust structure of subducting plate. The two types of subduction erosion models in Yap Trench exhibit a good case to reveal the process and mode of plate subducting in subduction

The elemental geochemistry of Lower Triassic shallow-marine carbonates from central Saudi Arabia: Implications for redox conditions in the immediate aftermath of the latest Permian mass extinction

NASA Astrophysics Data System (ADS)

Eltom, Hassan A.; Abdullatif, Osman M.; Babalola, Lamidi O.

2018-03-01

The southern margin of the Tethys Ocean was occupied by a broad, shallow continental shelf during the Permian-Triassic boundary interval, with the area of present-day Saudi Arabia located from 10° to 30° south of the paleo-equator. The strata deposited in modern Saudi Arabia in the aftermath of the latest Permian mass extinction (LPME) are dominated by oolitic microbialite limestone (OML), which are overlain by skeletal oolitic limestones (SOL) capped by dolostones and dolomitic limestones (DDL). This succession reflects changes in depositional setting, which can be potentially tied to redox conditions using redox sensitive trace elements and rare earth elements (REEs). Statistical analyses reveals that trace elements and REEs are associated with detrital material, and possibly with diagenetic minerals as well. Proxies such as the Y/Ho, Pr/Pr*, Smn/Ybn, Lan/Smn and Lan/Ybn ratios indicate that REEs do not record a seawater-like pattern, and cannot be used as redox indicator. The presence of a normal marine fauna implies oxic conditions during deposition of the DDL and SOL units. However, the OML unit, which represents the immediate aftermath of LPME, lacks both a normal marine fauna and reliable geochemical signals, making it difficult to infer redox conditions in the depositional environment. Similar to published data from sections that reflect shallow marine condition in the LPME of the Tethys Ocean, chemical index of alteration values are consistently high throughout the study succession, suggesting globally intense chemical weathering in the aftermath of the LPME. As a result, geochemical redox proxies in shallow marine carbonates of the Tethys Ocean are likely to be contaminated by detrital material that have been generated by chemical weathering, and thus, other methods are required to determine depositional redox conditions.

Wide-Field InfraRed Survey Telescope (WFIRST) Slitless Spectrometer: Design, Prototype, and Results

NASA Technical Reports Server (NTRS)

Gong, Qian; Content, David; Dominguez, Margaret; Emmett, Thomas; Griesmann, Ulf; Hagopian, John; Kruk, Jeffrey; Marx, Catherine; Pasquale, Bert; Wallace, Thomas;

Latest developments at the ALBA magnetic measurements laboratory

NASA Astrophysics Data System (ADS)

Marcos, J.; Massana, V.; García, L.; Campmany, J.

2018-02-01

ALBA is a third-generation synchrotron light source that has been in operation since 2012 near Barcelona. A magnetic measurements laboratory has been associated with the facility since its very early stages and has been active for the last 20 years. In the first part of this work, the different instruments available at the laboratory are described, and a brief overview of the measurement campaigns carried out during its 20 years of history is presented. In the second part, a more detailed description of the approach to Hall probe measurements adopted at ALBA is offered, with an explanation of the methods and ancillary equipment that have been developed along the years in order to improve the accuracy of the system. In the third part, a new concept of Hall probe bench devoted to the measurement of closed structures is presented. The in-house design and building of a prototype for such a bench is described, together with its mechanical and magnetic characterization. As a conclusion, the first results obtained with this bench are discussed.

Metal-Air Batteries: (Latest citations from the Aerospace Database)

NASA Technical Reports Server (NTRS)

1997-01-01

The bibliography contains citations concerning applications of metal-air batteries. Topics include systems that possess different practical energy densities at specific powers. Coverage includes the operation of air electrodes at different densities and performance results. The systems are used in electric vehicles as a cost-effective method to achieve reliability and efficiency. Zinc-air batteries are covered more thoroughly in a separate bibliography. (Contains 50-250 citations and includes a subject term index and title list.)

The Latest in Handheld Microscopes

ERIC Educational Resources Information Center

Wighting, Mervyn J.; Lucking, Robert A.; Christmann, Edwin P.

2004-01-01

Around 1590, Zacharias Jansenn of Holland invented the microscope. Jansenn, an eyeglass maker by trade, experimented with lenses and discovered that things appeared closer with combinations of lenses. Over the past 400 years, several refinements to microscopes have occurred, making it possible to magnify objects between 200 and 1,500 times their…

Latest advances in chronic pancreatitis.

PubMed

Enrique Domínguez-Muñoz, J

2016-09-01

This article summarizes some of the recent and clinically relevant advances in chronic pancreatitis. These advances mainly concern the definition of the disease, the etiological diagnosis of idiopathic disease, the correlation between fibrosis degree and pancreatic secretion in the early stages of chronic pancreatitis, the treatment of the disease and of pain, the clinical relevance of pancreatic exocrine insufficiency, and the diagnosis of autoimmune pancreatitis. A new mechanistic definition of chronic pancreatitis has been proposed. Genetic testing is mainly of help in patients with relapsing idiopathic pancreatitis. A significant correlation has been shown between the degree of pancreatic fibrosis as evaluated by elastography and pancreatic secretion of bicarbonate. New data supports the efficacy of antioxidants and simvastatin for the therapy of chronic pancreatitis. The pancreatoscopy-guided intraductal lithotripsy is an effective alternative to extracorporeal shock wave lithotripsy in patients with chronic calcifying pancreatitis. The presence of pancreatic exocrine insufficiency in patients with chronic pancreatitis is associated with a significant risk of cardiovascular events. Fine needle biopsy and contrast enhanced harmonic endoscopic ultrasonography are of help for the diagnosis of autoimmune pancreatitis and its differential diagnosis with pancreatic cancer. Copyright © 2016 Elsevier España, S.L.U. All rights reserved.

[Latest advances in chronic pancreatitis].

PubMed

Domínguez Muñoz, J Enrique

2015-09-01

This article summarizes some of the recent and clinically relevant advances in chronic pancreatitis. These advances mainly concern the early diagnosis of the disease, the treatment of symptoms and complications, mainly pain and pancreatic exocrine insufficiency, and the diagnosis and therapy of autoimmune pancreatitis. The multimodal dynamic endoscopic ultrasound-guided secretin-stimulated evaluation of the pancreas provides relevant morphological and functional information for the diagnosis of chronic pancreatitis at early stages. Extracorporeal shock wave lithotripsy in patients with calcifying pancreatitis and endoscopic pancreatic stent placement are effective alternatives for pain therapy in patients with chronic pancreatitis. Presence of pancreatic exocrine insufficiency in patients with chronic pancreatitis is associated with a significantly increase of mortality rate. Despite that, pancreatic enzyme replacement therapy is not prescribed in the majority of patients with pancreatic exocrine insufficiency, or it is prescribed at a low dose. The newly developed and commercialized needles for endoscopic ultrasound-guided pancreatic biopsy are effective in retrieving appropriate tissue samples for the histological diagnosis of autoimmune pancreatitis. Maintenance therapy with azathioprine is effective and safe to prevent relapses in patients with autoimmune pancreatitis. Copyright © 2015 Elsevier España, S.L.U. All rights reserved.

The latest buzz on bugs

USDA-ARS?s Scientific Manuscript database

Tree fruit-related entomological research currently being conducted at the USDA-ARS laboratory in Wapato, WA is reviewed. Scientists at the United States Department of Agriculture, Agricultural Research Service (USDA-ARS) in Wapato, WA conduct research on insect pests of tree fruits and potato. Th...

Latest View of Hurricane Joaquin

NASA Image and Video Library

2017-12-08

Hurricane Joaquin continued to intensify in the Bahamas on October 1 and NASA and NOAA satellites have been providing valuable data on the storm. NASA's GPM and Terra satellites and NOAA's GOES-East satellite provided rainfall, cloud extent, cloud height and other data to forecasters. Joaquin became a major hurricane today, October 1, reaching Category 3 status on the Saffir-Simpson Wind Scale. On October 1 at 1330 UTC (9:30 a.m. EDT) NOAA's GOES-East satellite captured this visible image of Hurricane Joaquin covering the southern Bahamas and extending over southeastern Cuba, and the island of Hispaniola (which includes Haiti and the Dominican Republic). Joaquin's eye had become completely visible now that the storm had reached Category 3 status. On October 1, a Hurricane Warning was in effect for the Central Bahamas, Northwestern Bahamas including the Abacos, Berry Islands, Eleuthera, Grand Bahama Island, and New Providence, The Acklins, Crooked Island, and Mayaguana in the southeastern Bahamas. A Hurricane Watch was in effect for Bimini and Andros Island, and a Tropical Storm Warning was in effect for the remainder of the southeastern Bahamas excluding the Turks and Caicos Islands and Andros Island. According to NHC, at 8 a.m. EDT (1200 UTC), the center of Hurricane Joaquin was located near latitude 23.2 North, longitude 73.7 West. That's just 10 miles (15 km) north of Samana Cays, Bahamas and about 75 miles (120 km) southeast of San Salvador, Bahamas. Joaquin was moving toward the west-southwest near 5 mph (7 kph), and this motion is expected to continue today. NHC noted that a turn toward the west- northwest is forecast tonight (Oct. 1), followed by a turn toward the north and an increase in forward speed on Friday, Oct. 2. On the forecast track, the center of Joaquin will move near or over portions of the central Bahamas today and tonight and pass near or over portions of the northwestern Bahamas on Friday. Maximum sustained winds are near 120 mph (195 km/h) with higher gusts. Joaquin is a category 3 hurricane on the Saffir-Simpson Hurricane Wind Scale. Some strengthening is forecast in the next day or so, with some fluctuations in intensity possible on Friday. Hurricane force winds extend outward up to 35 miles (55 km) from the center and tropical storm force winds extend outward up to 140 miles (220 km). The minimum central pressure just extrapolated by an Air Force Reserve Hurricane Hunter aircraft is 942 millibars. For updated forecasts, watches and warnings visit the National Hurricane Center (NHC) website: www.nhc.noaa.gov. Credit: NASA/NOAA GOES Project NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Latest developments in cryogenic safety

NASA Astrophysics Data System (ADS)

Webster, T.

1982-05-01

The Cryogenic Safety Manual, published under the auspices of the British Cryogenics Council, is summarized. Since an awareness of the physical properties of the cryogenic fluids being dealt with is considered important in directing attention to hazardous situations which may arise, the manual lists the more important properties, such as molecular weight, boiling point, and freezing point. Since hydrogen and helium are very light, the possibility arises of explosive mixtures being formed at high points in buildings. Since argon is unexpectedly heavy, its removal requires suction rather than blowing. It is also pointed out that the use of inert liquid nitrogen can lead to the creation of a noninert atmosphere which supports combustion because it contains oxygen. Attention is also given to the danger of asphyxiation posed by the growing use of inert gases.

Latest developments in cryogenic safety

NASA Astrophysics Data System (ADS)

Webster, T. J.

1983-03-01

The Cryogenic Safety Manual, sponsored by the British Cryogenics Council, was published over 10 years ago. A new updated version is now available. Some general aspects of cryogenic safety are highlighted, and attention is drawn to some of the more unusual hazardous situations. An awareness of the physical properties of the cryogenic fluids being dealt with is important in directing attention to hazardous situations which may arise. Because of this, the more important properties of the cryogenic fluids are given, such as molecular weight, boiling point and freezing point. From these properties, hazardous situations can be deduced. There are hidden dangers that are not always easy to spot. Some of the unexpected hazards, most of which have led to deaths, are: asphyxiation (anoxia), frost bites and hypothermia, explosions, and combustion. The aim of this publication is to help bring about increased safety in the production and use of cryogenic products through a deeper appreciation of the scientific, technological and administrative steps which must be made if accidents, some fatal, are to be voided in the future.

Latest developments in cryogenic safety

NASA Technical Reports Server (NTRS)

Webster, T. J.

1983-01-01

The Cryogenic Safety Manual, sponsored by the British Cryogenics Council, was published over 10 years ago. A new updated version is now available. Some general aspects of cryogenic safety are highlighted, and attention is drawn to some of the more unusual hazardous situations. An awareness of the physical properties of the cryogenic fluids being dealt with is important in directing attention to hazardous situations which may arise. Because of this, the more important properties of the cryogenic fluids are given, such as molecular weight, boiling point and freezing point. From these properties, hazardous situations can be deduced. There are hidden dangers that are not always easy to spot. Some of the unexpected hazards, most of which have led to deaths, are: asphyxiation (anoxia), frost bites and hypothermia, explosions, and combustion. The aim of this publication is to help bring about increased safety in the production and use of cryogenic products through a deeper appreciation of the scientific, technological and administrative steps which must be made if accidents, some fatal, are to be voided in the future.

Housing & woodworking: latest trends & impacts

Treesearch

Urs Buehlmann; Matt Bumgardner; Karen Koenig

2014-01-01

Trends in housing and other construction-related sectors continue to have a significant impact on the wood products industry, particularly cabinetry, furniture, millwork and components. This fifth annual survey assesses the market conditions for secondary woodworking manufacturers involved in construction-based sectors and includes information on their status and...

Search Hardware: Latest and Greatest.

ERIC Educational Resources Information Center

Alberico, Ralph

1988-01-01

Uses the different search environments of information brokers and institutional searchers to illustrate the factors that should be considered when selecting microcomputers for search operations. The factors discussed include speed, storage capabilities, displays, modems, printing technologies, facsimile transmission, and portability. A directory…

Latest medical applications of polypropylene.

PubMed

Van Lierde, Stijn

2004-06-01

PP volumes for use in medical applications increase every year for some obvious reasons. The polymer can be processed by practically all techniques and sterilisation and transparency processes, and its properties are continuously improved. Furthermore, it can replace many other materials, and is attractive from a cost and versatility perspective.

[Latest advances in acute pancreatitis].

PubMed

de-Madaria, Enrique

2015-09-01

The present article analyses the main presentations on acute pancreatitis at Digestive Disease Week 2015. Arterial pseudoaneurysm is an uncommon complication of acute pancreatitis (incidence 0.7%) and mortality from this cause is currently anecdotal. Diabetes mellitus has little impact on the clinical course of acute pancreatitis, unlike cirrhosis, which doubles the risk of mortality. Intake of unsaturated fat could be associated with an increased severity of acute pancreatitis and is a confounding factor in studies evaluating the relationship between obesity and morbidity and mortality. PET-CT (positron emission tomography-computed tomography) could be a non-invasive tool to detect infection of collections in acute pancreatitis. Peripancreatic fat necrosis is less frequent than pancreatic fat necrosis and is associated with a better clinical course. If the clinical course is poor, increasing the calibre of the percutaneous drains used in the treatment of infected necrosis can avoid surgery in 20% of patients. The use of low molecular-weight heparin in moderate or severe pancreatitis could be associated with a better clinical course, specifically with a lower incidence of necrosis. In acute recurrent pancreatitis, simvastatin is a promising drug for prophylaxis of new episodes of acute pancreatitis. Nutritional support through a nasogastric tube does not improve clinical course compared with oral nutrition. Copyright © 2015 Elsevier España, S.L.U. All rights reserved.

[Latest advances in acute pancreatitis].

PubMed

de-Madaria, Enrique

2013-10-01

The present article analyzes the main presentations on acute pancreatitis (AP) in Digestive Disease Week 2013. Perfusion computed tomography allows early diagnosis of pancreatic necrosis. Neutrophil gelatinase-associated lipocalin predicts the development of acute renal failure, severe AP and death. Factors associated with greater fluid sequestration in AP are alcoholic etiology, an elevated hematocrit, and the presence of criteria of systemic inflammatory response syndrome; fluid sequestration is associated with a worse outcome. True pseudocysts (fluid collections without necrosis for more than 4 weeks) are a highly infrequent complication in AP. Patients with necrotic collections have a poor prognosis, especially if associated with infection. A meta-analysis on fluid therapy suggests that early aggressive fluid administration is associated with higher mortality and more frequent respiratory complications. According to a meta-analysis, enteral nutrition initiated within 24 hours of admission improves the outcome of AP compared with later initiation of enteral nutrition. Pentoxifylline could be a promising alternative in AP; a double-blind randomized study showed that this drug reduced the length of hospital and intensive care unit stay, as well as the need for intensive care unit admission. The association of octreotide and celecoxib seems to reduce the frequency of organ damage compared with octreotide alone. Mild AP can be managed in the ambulatory setting through hospital-at-home units after a short, 24-hour admission. Copyright © 2013 Elsevier España, S.L. All rights reserved.

Beta Decay Study of the Tz = - 256Zn Nucleus and the Determination of the Half-Lives of a Few fp-shell Nuclei

NASA Astrophysics Data System (ADS)

Rubio, B.; Orrigo, S. E. A.; Kucuk, L.; Montaner-Pizá, A.; Fujita, Y.; Fujita, H.; Blank, B.; Gelletly, W.; Adachi, T.; Agramunt, J.; Algora, A.; Ascher, P.; Bilgier, B.; Cáceres, L.; Cakirli, R. B.; de France, G.; Ganioğlu, E.; Gerbaux, M.; Giovinazzo, J.; Grevy, S.; Kamalou, O.; Kozer, H. C.; Kurtukian-Nieto, T.; Marqués, F. M.; Molina, F.; Oktem, Y.; de Oliveira Santos, F.; Perrot, L.; Popescu, L.; Raabe, R.; Rogers, A. M.; Srivastava, P. C.; Susoy, G.; Suzuki, T.; Tamii, A.; Thomas, J. C.

2014-06-01

This paper concerns the experimental study of the β decay properties of few proton-rich fp-shell nuclei. The nuclei were produced at GANIL in fragmentation reactions, separated with the LISE spectrometer and stopped in an implantation detector surrounded by Ge detectors. The β-delayed gammas, β-delayed protons and the exotic β-delayed gamma-proton emission have been studied. Preliminary results are presented. The decay of the Tz = - 2 nucleus 56Zn has been studied in detail. Information from the β-delayed protons and β-delayed gammas has been used to deduce the decay scheme. The exotic beta-delayed gamma-proton decay has been observed for the first time in the fp-shell. The interpretation of the data was made possible thanks to the detailed knowledge of the mirror Charge Exchange (CE) process and the gamma de-excitation of the states in 56Co, the mirror nucleus of 56Cu.

Quenching of CO2(ν2) by O: New Results and Analysis

NASA Astrophysics Data System (ADS)

Dodd, J. A.; Castle, K. J.; Rhinehart, J. M.; Hwang, E. S.

2005-12-01

New results from ongoing laboratory measurements of CO2(ν2) + O vibrational energy transfer (VET) will be presented. The process is a key contributor to both the CO2 15-μm emission intensity and to upper atmospheric cooling in the 75-120 km altitude range. A 266-nm laser pulse photolyzes O3, producing O atoms and initiating a temperature jump, while transient diode laser absorption spectroscopy is used to monitor the CO2(ν2) level population. We report the latest measurement results, including improvements in the experiment that have mitigated vibrational cascading effects, and the development of a powerful global kinetic fitting routine to allow the simultaneous determination of the appropriate rate parameters from a large body of data. Predictions of upper atmospheric density and temperature are sensitive to the input value of the CO2(ν2) + O relaxation rate constant ko(ν2), including its temperature dependence. Aeronomic models imply that increasing CO2 levels from anthropogenic sources will cause the thermosphere to cool and contract over time. The model results are supported by analyses of satellite orbital motion data over the past 40 years, which are consistent with a few percent thermospheric density decrease per decade. This has important implications for spacecraft drag and orbital longevity. It also provides an interesting connection between a molecular-level parameter, the CO2 + O VET efficiency, and the macroscopic effects of atmospheric density and temperature.

[Combined closing-wedge high tibial osteotomy with arthroscopy for varus knee and medial compartment osteoarthritis: clinical results at a minimum follow-up for five years].

PubMed

Liu, Jin-Song; Li, Zhi-Yao

2013-09-01

To study the results of closing-wedge high tibial osteotomy and arthroscopy for the treatment of medial compartment osteoarthritis of the knee. From October 2005 to June 2007, 25 patients met with our inclusion criteria. All the patients with medial compartment knee osteoarthritis were treated with arthroscopy and closing-wedge high tibial osteotomy. There were 11 males and 14 females,with a mean age of 53 years old. The pre-operative HSS knee score was 67.6 +/- 2.8, FTA was (185.54 +/- 1.11) degrees, and aLPTA was (96.54 +/- 0.52) degrees in average. The patients were followed up and evaluated according to HSS knee score. The efficacy of the osteotomy was evaluated by FTA and aLPTA. All surgeries were successful without serious complication. All the patients were followed up, and the duration ranged from 5 to 7 years. The HSS was 85.5 +/- 3.7 at the 1st year and 80.3 +/- 5.4 at the latest follow-up. There was significant difference between every two scores of before operation and the two after operation (t = -33.135, P = 0.000; t = -13.215, P = 0.000). The FTA was (173.65 +/- 0.92) degrees at the 1st year and (174.34 +/- 0.53) degrees at the latest follow-up. There was significant difference between every two angles of before operation and after operation (t = 28.739, P = 0.000; t = 2.331, P = 0.048). The aLPTA was (87.32 +/- 0.33) degrees at the 1st year and (87.67 +/- 2.82) degrees at the latest follow-up. There was significant difference between every two angles of before operation and after operation (t = 37.264, P = 0.000; t = 2.469, P = 0.039). Indication is important and good surgical technique is critical for good clinical outcome. A detailed plan before operation is essential for the operation. Arthroscopy is helpful for treating the intra-articular pathology. The osteoarthritis is still in progress but in a slow mode. The combined method of arthroscopy and closing-wedge high tibial osteotomy is a reliable way for medial compartment osteoarthritis of the

Advancements in Micrometeorological Technique for Monitoring CH4 Release from Remote Permafrost Regions: Principles, Emerging Research, and Latest Updates

NASA Astrophysics Data System (ADS)

Burba, George; Budishchev, Artem; Gioli, Beniamino; Haapanala, Sami; Helbig, Manuel; Losacco, Salvatore; Mammarella, Ivan; Moreaux, Virginie; Murphy, Patrick; Oechel, Walter; Peltola, Olli; Rinne, Janne; Sonnentag, Oliver; Sturtevant, Cove; Vesala, Timo; Zona, Donatella; Zulueta, Rommel

2014-05-01

in permafrost regions have mostly been made with static chamber techniques, and few were done with the eddy covariance approach using closed-path analyzers. Although chambers and closed-path analyzers have advantages, both techniques have significant limitations, especially for remote or portable research in cold regions. Static chamber measurements are discrete in time and space, and particularly difficult to use over polygonal tundra with highly non-uniform micro-topography and active soil layer. Closed-path gas analyzers for measuring CH4 eddy fluxes require climate control, employ high-power pumps, and generally require grid power and infrastructure. As a result, spatial coverage of eddy covariance CH4 flux measurements in cold regions remains limited. Existing stations are often located near grid power sources and roads rather than in the middle of the methane-producing ecosystem, while those that are placed appropriately may require extraordinary efforts to build and maintain them, with large investments into manpower and infrastructure. In this presentation, basic principles of eddy covariance flux measurements are explained, along with details on the CH4, CO2 and H2O exchange measurements using low-power flux stations. Also included are latest updates on the emerging research utilizing such stations in remote permafrost regions, and on the 2013-2014 development of fully automated remote unattended flux station capable of processing data on-the-go to continuously output final CH4 release rates.

Latest trends in parts SEP susceptibility from heavy ions

NASA Technical Reports Server (NTRS)

Nichols, Donald K.; Smith, L. S.; Soli, George A.; Koga, R.; Kolasinski, W. A.

1989-01-01

JPL and Aerospace have collected a third set of heavy-ion single-event phenomena (SEP) test data since their last joint IEEE publications in December 1985 and December 1987. Trends in SEP susceptibility (e.g., soft errors and latchup) for state-of-the-art parts are presented. Results of the study indicate that hard technologies and unacceptably soft technologies can be flagged. In some instances, specific tested parts can be taken as candidates for key microprocessors or memories. As always with radiation test data, specific test data for qualified flight parts is recommended for critical applications.

[Scope of the latest RE-LY substudies: clinical implications].

PubMed

Ruiz-Giménez Arrieta, N

2012-03-01

The approval of the use of dabiatran in stroke prevention in patients with nonvalvular atrial fibrilation (NVAF) is based on the results of the RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) trial, one of the largest studies to date in this entity. In this trial, dabigatran showed similar safety and efficacy to warfarin in primary and secondary prevention of stroke in patients with AF. At a dose of 150 mg twice daily, dabigatran was superior to warfarin in the prevention of stroke or systemic embolism and the 110 mg dose twice daily showed similar efficacy and greater safety, given the lower incidence of hemorrhage. These results were consistently found in the various subanalyses, with some slight differences of interest for clinical practice. The ideal candidates for dabiatran are patients with NVAF suitable for cardioversion, who require short periods of anticoagulation, patients in remote geographical areas with difficulty in achieving good anticoagulation control or good control with anti-vitamin K treatment due to IRN fluctuations, and patients with a low risk of hemorrhage and a CHADS score ≥ 3 and/or with prior stroke, whenever there are no contraindications. The choice of dabigatran dose should be evaluated according to the patient's individual characteristics (caution must be exercised when prescribing this drug in the elderly and in renal insufficiency) and embolic and/or hemorrhagic risk. Studies of the long-term safety of this drug, pharmacoeconomic analyses in Spain and post-commercialization pharmacovigilance data are required before the definitive uses of this drug can be established. Copyright © 2012 Elsevier España, S.L. All rights reserved.

Beam tracking with micromegas & wire chambers in secondary electron detection configuration

NASA Astrophysics Data System (ADS)

Voštinar, M.; Fernández, B.; Pancin, J.; Alvarez, M. A. G.; Chaminade, T.; Damoy, S.; Doré, D.; Drouart, A.; Druillole, F.; Frémont, G.; Kebbiri, M.; Materna, T.; Monmarthe, E.; Panebianco, S.; Papaevangelou, T.; Riallot, M.; Savajols, H.; Spitaels, C.

2013-12-01

The focal plane of S3 (Super Separator Spectrometer), a new experimental area of SPIRAL2 at GANIL, will be used for identification of nuclei, and requires the reconstruction of their trajectories and velocities by the Time Of Flight (TOF) method. Classical tracking detectors used in-beam would generate a lot of angular and energy straggling due to their thickness. One solution is the use of a SED (Secondary Electron Detection), which consists of a thin emissive foil in beam coupled to a low pressure gaseous detector out of the beam, for the detection of secondary electrons ejected from the foil. Moreover, this type of detector can be used for classical beam tracking at low energies, or for example at NFS (GANIL) for the FALSTAFF experiment for the reconstruction of fission fragments trajectories. Several low pressure gaseous detectors such as wire chambers and Micromegas have been constructed and tested since 2008. High counting rate capabilities and good time resolution obtained in previous tests motivated the construction of a new real-size 2D prototype wire chamber and a 2D bulk Micromegas at low pressure. For the first time, spatial resolution of the Micromegas at low pressure (below 20 mbar) in the SED configuration was measured. Different tests have been performed in order to characterize time and spatial properties of both prototypes, giving spatial resolution in the horizontal (X) direction of 0.90(0.02) mm FWHM for the real size prototype and 0.72(0.08) mm FWHM for Micromegas, and a time resolution of ~ 110(25) ps for the real size prototype.

Constellations Solar Array Design, Industrialization And In-Flight Results

NASA Astrophysics Data System (ADS)

Combet, Yannick; Clapper, Paul

2011-10-01

Constellations has become a recurring opportunities in Thales Alenia Space since 3 majors programs had been awarded: Globalstar was the pathfinder with 48 flight sets followed by O3b with 8 an the latest is Iridium Next with 81 models. For these 3 programs, the Solar Array is fully developed, validated and produced by Thales Alenia Space with major subcontractors. This new segment of the activity leads to new development, design and industrialization approaches. This paper describes the Solar Array design and the alternative to current approach build and applied with the following drivers: - the low recurring cost and mass of the flight hardware, with particular attention on the Solar Array, - high robustness for system integration and in-orbit operations, - a long mission duration (typically 15 years in LEO) leading to take into account high number of thermal cycles (60 to 72.000 cycles), - new production concept with strict schedule management, - design segmented in subassemblies to reduce the integration time as well as a improved trouble shooting management, - delivery rate up to 1 wing per week and after learning curve effect, a integration duration divided by 3 compared to current production, - a delivery of a qualified PFM solar array in 22 months including the design to producibility constrains, This demanding requirement for delivery scheme and cost target did not jeopardize the requirements and standards for space application. After a brief description of the way the main drivers have been considered, the paper presents the main features and performances of the subsystem and shows the main validation test results. The first launch was successful in October 2010 and the first in-orbit results are presented.

Recent Results on Central Compact Objects

NASA Astrophysics Data System (ADS)

Halpern, Jules P.; Gotthelf, E. V.

2011-09-01

We will review the latest observational results and theoretical puzzles about the class of central compact objects (CCOs) in supernova remnants (SNRs), 10 isolated neutron stars (NSs) with steady, thermal X-ray emission and absence of a surrounding pulsar wind nebula. Three CCOs have detected X-ray pulsations, with periods of 0.105, 0.112, and 0.424 s. X-ray timing studies reveal that their spin-down rates are extremely small, implying dipole magnetic fields of only 3.e10-1.e11 G, which is unprecedented among the population of young pulsars. In the absence of a stronger magnetic field, it is difficult to explain the high temperatures of their surface hot spots, which may instead require a magnetic field configuration that is different from a centered dipole. While CCOs are inconspicuous relative to ordinary young pulsars and active magnetars, that they are found in SNRs in comparable numbers to other classes of NSs implies that they must represent a significant fraction of NS births. Nevertheless, they fall in a region of the P,P-dot diagram for radio pulsars that is underpopulated, so it is not clear if CCOs are intrinsically radio quiet, and what happens to their descendants, the "orphaned CCOs" whose SNRs have dissipated. It has been speculated that if their magnetic fields were initially strong but were buried by prompt fall-back of supernova debris, then the dipole field may eventually diffuse back to the surface, and CCOs could join the main population of ordinary pulsars. We will also discuss how the absence of detected pulsations from the majority of CCOs makes them difficult to distinguish from magnetars in quiescence, which have X-ray spectra and luminosities similar to those of CCOs. However, they can be distinguished with long-term monitoring, since magnetars are eventually variable, while CCOs are steady X-ray emitters.

Latest animal models for anti-HIV drug discovery.

PubMed

Sliva, Katja

2015-02-01

HIV research is limited by the fact that lentiviruses are highly species specific. The need for appropriate models to promote research has led to the development of many elaborate surrogate animal models. This review looks at the history of animal models for HIV research. Although natural animal lentivirus infections and chimeric viruses such as chimera between HIV and simian immunodeficiency virus and simian-tropic HIV are briefly discussed, the main focus is on small animal models, including the complex design of the 'humanized' mouse. The review also traces the historic evolution and milestones as well as depicting current models and future prospects for HIV research. HIV research is a complex and challenging task that is highly manpower-, money- and time-consuming. Besides factors such as hypervariability and latency, the lack of appropriate animal models that exhibit and recapitulate the entire infectious process of HIV, is one of the reasons behind the failure to eliminate the lentivirus from the human population. This obstacle has led to the exploitation and further development of many sophisticated surrogate animal models for HIV research. While there is no animal model that perfectly mirrors and mimics HIV infections in humans, there are a variety of host species and viruses that complement each other. Combining the insights from each model, and critically comparing the results obtained with data from human clinical trials should help expand our understanding of HIV pathogenesis and drive future drug development.

Results from the latest SN-4 multi-parametric benthic observatory experiment (MARsite EU project) in the Gulf of Izmit, Turkey: oceanographic, chemical and seismic monitoring

NASA Astrophysics Data System (ADS)

Embriaco, Davide; Marinaro, Giuditta; Frugoni, Francesco; Giovanetti, Gabriele; Monna, Stephen; Etiope, Giuseppe; Gasperini, Luca; Çağatay, Namık; Favali, Paolo

2015-04-01

An autonomous and long-term multiparametric benthic observatory (SN-4) was designed to study gas seepage and seismic energy release along the submerged segment of the North Anatolian Fault (NAF). Episodic gas seepage occurs at the seafloor in the Gulf of Izmit (Sea of Marmara, NW Turkey) along this submerged segment of the NAF, which ruptured during the 1999 Mw7.4 Izmit earthquake. The SN-4 observatory already operated in the Gulf of Izmit at the western end of the 1999 Izmit earthquake rupture for about one-year at 166 m water depth during the 2009-2010 experiment (EGU2014-13412-1, EGU General Assembly 2014). SN-4 was re-deployed in the same site for a new long term mission (September 2013 - April 2014) in the framework of MARsite (New Directions in Seismic Hazard assessment through Focused Earth Observation in the Marmara Supersite, http://marsite.eu/ ) EC project, which aims at evaluating seismic risk and managing of long-term monitoring activities in the Marmara Sea. A main scientific objective of the SN-4 experiment is to investigate the possible correlations between seafloor methane seepage and release of seismic energy. We used the same site of the 2009-2010 campaign to verify both the occurrence of previously observed phenomena and the reliability of results obtained in the previous experiment (Embriaco et al., 2014, doi:10.1093/gji/ggt436). In particular, we are interested in the detection of gas release at the seafloor, in the role played by oceanographic phenomena in this detection, and in the association of gas and seismic energy release. The scientific payload included, among other instruments, a three-component broad-band seismometer, and gas and oceanographic sensors. We present a technical description of the observatory, including the data acquisition and control system, results from the preliminary analysis of this new multidisciplinary data set, and a comparison with the previous experiment.

The sequence stratigraphy of the latest Cretaceous sediments of northern Wyoming: The interplay of tectonic and eustatic controls on foreland basin sedimentation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hicks, J.F.; Tauxe, L.

1992-01-01

A west-east chronostratigraphic correlation has been made of the latest Cretaceous sediments of northern Wyoming. Five sections from Jackson Hole to Red Bird have been dated magnetostratigraphically (C34N-C26R) and radiometrically (81-68 Ma), and integrated with the ammonite biostratigraphy of the Niobrara and Pierre Shale. Four major sequence surfaces have been identified in section and the time missing within the unconformities has been measured and traced laterally. These bounding unconformities define six alloformations. The lowest straddles the C34N/C33R chronic boundary and contains the Cody, Telegraph Creek and Eagle Fms. The second ranges from the mid- to upper part of C33N ofmore » C32R and contains the Claggett and Judith River/Mesaverde Fms. The third (C32R ) is the Teapot Sandstone Member of the Mesaverde Fm. The fourth extends from the lower to upper part of C32N or to mid-C31R and includes the Bearpaw Shale and Meeteetse Fm. The fifth extends from C31N to C30N or C29N and includes the Harebell and Lance Fms. The base of the uppermost alloformation has been identified within C26R in the uppermost alloformation has been identified within C26R in the lowermost Fort Union. The unconformable surfaces are angular adjacent to the Sevier Thrust Belt but form paraconformities or hiatuses in the marine units to the east. The unconformities are eustatically controlled throughout the Campanian, but become tectonically driven in the Maastrichtian with the onset of rapid foredeep subsidence in Jackson Hole, and forebulge uplift in the Bighorn and Wind River Basin region which correlates exactly to the rapid regression of the Bearpaw Sea from the area in the range of Baculites clinolobatus.« less

Statistical and Hydrological Evaluation of TRMM-Based Multi-Satellite Precipitation Analysis over the Wangchu Basin of Bhutan: Are the Latest Satellite Precipitation Products 3B42V7 Ready for Use in Ungauged Basins?

NASA Technical Reports Server (NTRS)

Xue, Xianwu; Hong, Yang; Limaye, Ashutosh S.; Gourley, Jonathan; Huffman, George J.; Khan, Sadiq Ibrahim; Dorji, Chhimi; Chen, Sheng

2013-01-01

The objective of this study is to quantitatively evaluate the successive Tropical Rainfall Measuring Mission (TRMM) Multi-satellite Precipitation Analysis (TMPA) products and further to explore the improvements and error propagation of the latest 3B42V7 algorithm relative to its predecessor 3B42V6 using the Coupled Routing and Excess Storage (CREST) hydrologic model in the mountainous Wangchu Basin of Bhutan. First, the comparison to a decade-long (2001-2010) daily rain gauge dataset reveals that: 1) 3B42V7 generally improves upon 3B42V6s underestimation both for the whole basin (bias from -41.15 to -8.38) and for a 0.250.25 grid cell with high-density gauges (bias from -40.25 to 0.04), though with modest enhancement of correlation coefficients (CC) (from 0.36 to 0.40 for basin-wide and from 0.37 to 0.41 for grid); and 2) 3B42V7 also improves its occurrence frequency across the rain intensity spectrum. Using the CREST model that has been calibrated with rain gauge inputs, the 3B42V6-based simulation shows limited hydrologic prediction NSCE skill (0.23 in daily scale and 0.25 in monthly scale) while 3B42V7 performs fairly well (0.66 in daily scale and 0.77 in monthly scale), a comparable skill score with the gauge rainfall simulations. After recalibrating the model with the respective TMPA data, significant improvements are observed for 3B42V6 across all categories, but not as much enhancement for the already well-performing 3B42V7 except for a reduction in bias (from -26.98 to -4.81). In summary, the latest 3B42V7 algorithm reveals a significant upgrade from 3B42V6 both in precipitation accuracy (i.e., correcting the underestimation) thus improving its potential hydrological utility. Forcing the model with 3B42V7 rainfall yields comparable skill scores with in-situ gauges even without recalibration of the hydrological model by the satellite precipitation, a compensating approach often used but not favored by the hydrology community, particularly in ungauged basins.

Molecules from Clouds to Planets: Sweet Results from Alma

NASA Astrophysics Data System (ADS)

van Dishoeck, Ewine

2017-06-01

One of the most exciting developments in astronomy is the discovery of thousands of planets around stars other than our Sun. But how do these exo-planets form, and which chemical ingredients are available to build them? Thanks to powerful new telescopes, especially the Atacama Large Millimeter/submillimeter Array (ALMA), astronomers are starting to address these age-old questions scientifically. Stars and planets are born in the cold and tenuous clouds between the stars in the Milky Way. In spite of the extremely low temperatures and densities, a surprisingly rich and interesting chemistry occurs in these interstellar clouds, as evidenced by the detection of more than 180 different molecules. Highly accurate spectroscopic data are key to their identification, and examples of the continued need and close interaction between laboratory work and astronomical observations will be given. ALMA now allows us to zoom in on solar system construction for the first time. Spectral scans of the birth sites of young stars contain tens of thousands of rotational lines. Water and a surprisingly rich variety of organic materials are found, including simple sugars and high abundances of deuterated species. How are these molecules formed? Can these pre-biotic molecules end up on new planets and form the basis for life elsewhere in the universe? Stay tuned for the latest analyses and also a comparison with recent results from the Rosetta mission to comet 67 P/C-G in our own Solar System.

Radiation damage induced in Al2O3 single crystal by 90 MeV Xe ions

NASA Astrophysics Data System (ADS)

Zirour, H.; Izerrouken, M.; Sari, A.

2015-12-01

Radiation damage induced in Al2O3 single crystal by 90 MeV Xe ions were investigated by optical absorption measurements, Raman spectroscopy and X-ray diffraction (XRD) techniques. The irradiations were performed at the GANIL accelerator in Caen, France for the fluence in the range from 1012 to 6 × 1013 cm-2 at room temperature under normal incidence. The F+ and F22+ centers kinetic as a function of fluence deduced from the optical measurements explains that the single defects (F and F+) aggregate to F center clusters (F2 , F2+, F22+) during irradiation at high fluence (>1013 cm-2). Raman and XRD analysis reveal a partial disorder of 40% of Al2O3 in the studied fluence range in accordance with Kabir et al. (2008) study. The result suggests that this is due to the stress relaxation process which occurs at high fluence (>1013 cm-2).

N/Z effect on reaction mechanisms cross sections in the 78Kr + 40Ca and 86Kr + 48Ca collisions at 10A MeV

NASA Astrophysics Data System (ADS)

Gnoffo, B.; Pirrone, S.; Politi, G.; La Commara, M.; Wieleczko, J. P.; De Filippo, E.; Russotto, P.; Trimarchi, M.; Vigilante, M.; Ademard, G.; Auditore, L.; Beck, C.; Bercenau, I.; Bonnet, E.; Borderie, B.; Cardella, G.; Chibihi, A.; Colonna, M.; De Luca, S.; Dell'Aquila, D.; D'Onofrio, A.; Frankland, J. D.; Lanzalone, G.; Lautesse, P.; Lebhertz, D.; Le Neidre, N.; Lombardo, I.; Martorana, N. S.; Mazurek, N.; Norella, S.; Pagano, A.; Pagano, E. V.; Papa, M.; Piasecki, E.; Porto, F.; Quattrocchi, L.; Rizzo, F.; Spadaccini, G.; Trifirò, A.; Verde, G.

2017-11-01

Nuclear reactions between medium-mass nuclei at low bombarding energy are characterized by the competition between binary and evaporation processes in the compound nucleus decay. A study of the influence of the neutron richness of the entrance channel on the decay paths of the compound nuclei formed in the 78Kr + 40Ca and 86Kr + 48Ca at 10MeV/A is presented. The experiment has been performed at Laboratori Nazionali del Sud by using the CHIMERA 4 π multidetector for charged particles. The kinematical characteristics of the two reactions support the conclusion of a production of the IMFs via long-lived system and the global features suggest a different competition among the various reaction channels. The cross sections of the mechanisms responsible for the fragments production have been extracted. Besides the results relative to the n-poor system are compared to those obtained at GANIL, performed at 5.5A MeV, in order to study the energy influence on the mechanisms.

β decay of the exotic Tz=-2 nuclei 48Fe,52Ni , and 56Zn

NASA Astrophysics Data System (ADS)

Orrigo, S. E. A.; Rubio, B.; Fujita, Y.; Gelletly, W.; Agramunt, J.; Algora, A.; Ascher, P.; Bilgier, B.; Blank, B.; Cáceres, L.; Cakirli, R. B.; Ganioǧlu, E.; Gerbaux, M.; Giovinazzo, J.; Grévy, S.; Kamalou, O.; Kozer, H. C.; Kucuk, L.; Kurtukian-Nieto, T.; Molina, F.; Popescu, L.; Rogers, A. M.; Susoy, G.; Stodel, C.; Suzuki, T.; Tamii, A.; Thomas, J. C.

2016-04-01

The results of a study of the β decays of three proton-rich nuclei with Tz=-2 , namely 48Fe,52Ni , and 56Zn, produced in an experiment carried out at GANIL, are reported. In all three cases we have extracted the half-lives and the total β -delayed proton emission branching ratios. We have measured the individual β -delayed protons and β -delayed γ rays and the branching ratios of the corresponding levels. Decay schemes have been determined for the three nuclei, and new energy levels are identified in the daughter nuclei. Competition between β -delayed protons and γ rays is observed in the de-excitation of the T =2 isobaric analog states in all three cases. Absolute Fermi and Gamow-Teller transition strengths have been determined. The mass excesses of the nuclei under study have been deduced. In addition, we discuss in detail the data analysis taking as a test case 56Zn, where the exotic β -delayed γ -proton decay has been observed.

First results of infrared thermography applied to the evaluation of hydraulic conductivity in rock masses

NASA Astrophysics Data System (ADS)

Pappalardo, Giovanna

2018-03-01

An innovative methodological approach using infrared thermography (IRT) provides a potential contribution to the indirect assessment of hydraulic conductivity of jointed rock masses. This technique proved a suitable tool to evaluate the degree of fracturing of rock masses along with their discontinuity systems, which expedite water flow within the rock mass itself. First, based on the latest scientific outcomes on the application of IRT to the geomechanics of rock systems, rock mass surveys were carried out at different outcrops (dolostone, limestone and porphyroid) and hydraulic conductivity was empirically assessed through approaches well known in the international literature. Then, IRT campaigns were performed at each surveyed rock mass, with the purpose of evaluating the corresponding Cooling Rate Index, strictly linked to the cooling attitude of the rock. Such index was correlated with the assessed hydraulic conductivity and satisfactory regression equations were achieved. The interesting results show that hydraulic conductivity values are likely to be linked with the cooling behavior of rock masses, which, in turn, is affected by spacing, aperture and persistence of discontinuities.

Carbon Dioxide and Water Vapor Concentrations, Co-spectra and Fluxes from Latest Standardized Automated CO2/H2O Flux Systems versus Established Analyzer Models

NASA Astrophysics Data System (ADS)

Burba, G. G.; Kathilankal, J. C.; Begashaw, I.; Franzen, D.; Welles, J.; McDermitt, D. K.

2017-12-01

Spatial and temporal flux data coverage have improved significantly in recent years, due to standardization, automation and management of data collection, and better handling of the generated data. With more stations and networks, larger data streams from each station, and smaller operating budgets, modern tools are required to effectively and efficiently handle the entire process.These tools should produce standardized verifiable datasets, and provide a way to cross-share the standardized data with external collaborators to leverage available funding, and promote data analyses and publications. In 2015, new open-path and enclosed flux measurement systems1 were developed, based on established gas analyzer models2,3, with the goal of improving stability in the presence of contamination, refining temperature control and compensation, and providing more accurate gas concentration measurements. In 2017, the new open-path system was further refined to simplify hardware configuration, and to reduce power consumption and cost. Additionally, all new systems incorporate complete automated on-site flux calculations using EddyPro® Software4 run by a weatherized remotely-accessible microcomputer to provide standardized traceable data sets for fluxes and supporting variables. This presentation will describe details and results from the field tests of the new flux systems, in comparison to older models and reference instruments. References:1 Burba G., W. Miller, I. Begashaw, G. Fratini, F. Griessbaum, J. Kathilankal, L. Xu, D. Franz, E. Joseph, E. Larmanou, S. Miller, D. Papale, S. Sabbatini, T. Sachs, R. Sakai, D. McDermitt, 2017. Comparison of CO2 Concentrations, Co-spectra and Flux Measurements between Latest Standardized Automated CO2/H2O Flux Systems and Older Gas Analysers. 10th ICDC Conference, Switzerland: 21-25/08 2 Metzger, S., G. Burba, S. Burns, P. Blanken, J. Li, H. Luo, R. Zulueta, 2016. Optimization of an enclosed gas analyzer sampling system for measuring eddy

Latest Miocene-Pliocene Tiliviche Paleolake, Atacama Desert, Northern Chile 19.5°S: Paleoclimatic and Paleohydrologic Implications

NASA Astrophysics Data System (ADS)

Kirk-Lawlor, N. E.; Jordan, T. E.; Rech, J.; Lehmann, S.

2010-12-01

Endorheic paleolake deposits of diatomite, mudstone, sandstone, and evaporites are exposed in the Atacama Desert of northern Chile. This study focuses on a major latest Miocene-Pliocene paleolake system centered at 19.5°S, near Tiliviche. A diatiomite unit, up to 35m thick, composed of 0.2-1.5m thick beds of massive, white diatiomite, free of plant matter and root traces, is interpreted have formed from lacustrine diatom blooms. At its maximum extent, the lake would have had a surface area of roughly 200 km2, based on the extent of the diatomite unit, and might have been 50-100 m deep, as inferred by the relationship between the diatomite unit and modern topography. The Tiliviche paleolake initially formed before 6.4 Ma, and much of its sedimentary record formed under a wetter climatic and hydrologic regime than the present. Prior to 3.5 Ma, the lake had evolved into a groundwater-fed saltpan. Polygonally fractured efflorescent halite evaporite and bedded gypsum and gypsarenite evaporite deposits that overlie the diatomite unit are evidence of this saltpan environment. The modern Atacama Desert is hyperarid, with an average precipitation of 2 mm/yr in the driest areas. The paleosol record demonstrates that hyperarid conditions dominated this region since the middle Miocene, albeit with multiple fluctuations to less arid conditions of short to moderately long duration. This hyperaridity is due to the desert’s latitude, ocean currents and the rainshadow created by the Andes. There is no evidence that the rainshadow effect has diminished since the late Miocene, hence global climate changes affecting ocean temperatures and atmospheric patterns likely caused the wetter periods in the Atacama. In particular, prior workers noted wetter conditions in the region ~6-5 Ma, followed by a return to hyper-arid conditions. The regional Pliocene return to hyperaridity coincided with the desiccation of the Tiliviche endorheic lake system. During the late Miocene (~6-5 Ma) wetter

Use of XenX™, the latest ureteric occlusion device with guide wire utility: results from a prospective multicentric comparative study.

PubMed

Sanguedolce, Francesco; Montanari, Emanuele; Alvarez-Maestro, Mario; Macchione, Nicola; Hruby, Stephan; Papatsoris, Athanasios; Kallidonis, Panagiotis; Villa, Luca; Honeck, Patrick; Traxer, Olivier; Greco, Francesco

2016-11-01

This is a prospective multicentric comparative study evaluating the performance of XenX-a new dual-purpose device for the prevention of stone fragments migration during ureteroscopic lithotripsy (URS). Between March 2014 and January 2015, 41 patients undertaking URS + XenX were matched with 41 patients undergoing standard URS. Patients included had unilateral ureteric stone(s) of 0.5-1.5 cm in maximum size. Demographics, complication rates and surgical outcomes were recorded for comparison. A Likert-like 5-grade scoring system was used for surgeons' evaluation of XenX properties. Cost analysis was performed by comparing weighted mean costs of the relevant procedures. Patients' characteristics between the two groups were comparable. Lasering time was longer for XenX group (13.59 vs. 5.17 min; p = 0.0001) whilst use of basket and need of JJ stent insertion was more frequent in control group (19.5 vs. 97.6 %; p = 0.0001 and 22 vs. 35 %; p = 0.001, respectively). Intra-operative SFR was significantly higher for XenX group (100 vs. 85.4 %; p = 0.0001), but not at 4-week follow-up, after ancillary procedures were needed in 17.1 % of the control group. Surgeons' evaluations for XenX were suboptimal for "Ease of Basketing" (2/5) and "Advancement of double J stent" (3/5). The use of XenX increased costs of procedures, but spared the costs associated to ancillary procedures and stent removals. XenX confirmed to be a safe and effective device especially for the treatment of upper ureteric tract stones; moreover, XenX may reduce the risk for the need of auxiliary procedures and for the insertion of a JJ stent.

Properties of the Lunar Interior: Preliminary Results from the GRAIL Mission

NASA Technical Reports Server (NTRS)

Williams, James G.; Konopliv, Alexander S.; Asmar, Sami W.; Lemoine, Frank G.; Melosh, H. Jay; Neumann, Gregory A.; Phillips, Roger J.; Smith, David E.; Solomon, Sean C.; Watkins, Michael M.;

Evaluating Surface Flux Results from CERES-FLASHFlux

NASA Astrophysics Data System (ADS)

Wilber, A. C.; Stackhouse, P. W., Jr.; Kratz, D. P.; Gupta, S. K.; Sawaengphokhai, P.

2016-12-01

The Clouds and Earth's Radiant Energy System (CERES) mission provides TOA (Top-of-Atmosphere) and surface radiative flux products for each CERES footprint (Single Scanner Footprint) and also time integrated and spatially averaged (TISA) to provide 1ox1o fluxes at various temporal averages. The CERES TISA products are available to the public within 3-6 months of observation. The CERES Fast Longwave and SHortwave radiative Flux (FLASHFlux) data products were developed to provide a rapid release version of the CERES data products. FLASHFlux data products are made available to the research and applications communities within one week of the satellite observations. Over the last several years, the CERES team has contributed to a section on the variability of radiation budget at the Top-of-Atmosphere in the annual "State of the Climate Report" published in BAMS using CERES TISA and FLASHFlux data products. Recently, the FLASHFlux data were used to investigate the radiative impacts of the intense 2015-2016 El Nino event. In addition FLASHFlux date are routinely used by applied science in energy related and agricultural sectors. The current version of FLASHFlux is being upgraded to FLASHFlux Version4A to improve consistency with the climate quality Edition 4 CERES data products. This presentation will describe the planned changes including the change to the latest meteorological product from Global Modeling and Assimilation Office (GMAO), GEOS FP-IT (5.12.4). GEOS 5.12.4 is an assimilation that is consistent with MERRA-2. We present comparisons of global and regional changes in the TOA and surface radiative fluxes as a result of the upgrade for both longwave (LW) and shortwave (SW) surface fluxes. We also compare the data products against ground measurements using data from the Baseline Surface Radiation Network (BSRN) - including NOAA SURFRAD, Atmospheric Radiation Measurement (ARM) and Ocean buoy measurements from Woods Hole Oceanographic Institute (WHOI).

An industry update: the latest developments in therapeutic delivery.

PubMed

Steinbach, Oliver C

2018-02-01

The present industry update covers the period 1 October-31 October 2017, with information sourced from company press releases, regulatory and patent agencies as well as scientific literature. While the corporate news in October was traditionally dominated by the announcement of the third quarter results, with most of them showing market and revenue growth but also an increasing number of initial public offerings after years of slower financial development, we also saw trends continuing toward an increasing number of convergences of drugs with nanotechnology, devices and 21st century information technology. Whether it is using E Ink's 'Smart Patch', AstraZeneca's autoinjector, Elektrofi's Elektroject suspensions or NanOlogy's NanoPac, there is an ever increasing number of combinations dof devices, drugs and applications reaching, more and more the clinic and the market. Controlled release is another feature increasingly addressed by many of the above innovations. For example, the drug-loaded x-ray imageable microscopic beads that have been developed by researchers at UCL Cancer Institute (London, UK) take this one step further in order to pursue local, controlled and in situ validated local delivery.

Seismic and chronostratigraphic results from SHALDRIL II, northwestern Weddell Sea

USGS Publications Warehouse

Anderson, J.B.; Wellner, J.; Wise, S.; Bohaty, S.; Manley, P.; Smith, T.; Weaver, F.; Kulhanek, D.

2007-01-01

The 2006 SHALDRIL II cruise was conducted in the northwestern Weddell Sea, with primary drilling targets in the James Ross Basin. A site drilled along the northern edge of the James Ross Basin sampled either latest Eocene or earliest Oligocene deposits, providing a lower chronostratigraphic benchmark for our seismic stratigraphic age model. Severe sea ice conditions forced abandonment of several of the James Ross Basin sites. Three alternate sites were drilled along the southern flank of the Joinville Plateau. Seismic data from the area show a thick, southward dipping stratigraphic succession with no conspicuous gaps. Three drill sites sampled this succession and recovered Oligocene, middle Miocene, and early Pliocene strata overlain by a thin drape of Pleistocene deposits. The Pliocene-Miocene boundary appears to be represented by a disconformity within the cored interval. Otherwise, this is one of the most complete post-Eocene successions anywhere on Antarctica and its adjacent margins

Distraction for proximal interphalangeal joint contractures: long-term results.

PubMed

Houshian, Shirzad; Jing, Shan Shan; Kazemian, Gholam Hussein; Emami-Moghaddam-Tehrani, Mohammad

2013-10-01

To report the medium- to long-term outcomes of joint distraction using a unilateral external fixator in the treatment of chronic post-traumatic proximal interphalangaeal (PIP) joint contractures. Between September 2001 and October 2011, 94 consecutive patients (98 PIP joints) with a mean age of 43 years (range, 17-69 y) were treated with external fixation for chronic flexion deformity of the PIP joint from trauma. The average time from injury to surgery was 48 months (range, 6-84 mo), and the duration of joint distraction was 10 days (range, 7-22 d). Patients were followed for a mean period of 54 months (range, 12-72 mo). The average gain in joint flexion was 25° and in joint extension was 40°. The mean improvement in the active range of movement was 67° (range. 30°-90°). There was no loss of motion on the latest follow-up. Patients younger than 40 years fared slightly better than those older than 40 years. Two patients developed swelling, pain, and erythema during treatment, which resolved upon temporarily stopping the distraction process. There were 12 cases of superficial pin-site infections, which were managed conservatively without serious complications or adverse outcome. External fixation is a simple and effective treatment modality for chronic traumatic PIP joint contractures with good predictable medium- to long-term results. Careful patient selection and monitoring are required. Copyright © 2013 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

Chronic obstructive pulmonary disease exacerbations: latest evidence and clinical implications

PubMed Central

Qureshi, Hammad; Sharafkhaneh, Amir

2014-01-01

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide and results in an economic and social burden that is both substantial and increasing. The natural history of COPD is punctuated by exacerbations which have major short- and long-term implications on the patient and healthcare system. Evidence-based guidelines stipulate that early detection and prompt treatment of exacerbations are essential to ensure optimal outcomes and to reduce the burden of COPD. Several factors can identify populations at risk of exacerbations. Implementing prevention measures in patients at risk is a major goal in the management of COPD. PMID:25177479

An industry update: the latest developments in therapeutic delivery.

PubMed

Simpson, Iain

2017-02-01

This Industry Update covers the period from 1 October through to 31 October 2016, and is based on information sourced from company press releases, scientific literature, patents and various news websites. The month saw several news items covering drug-delivery devices, including a new sensor to monitor and support the use of inhalers; launch in the UK of a new autoinjector for Cimzia ® , UCB's rheumatoid arthritis drug; and approval of Roche's Lucentis ® in a prefilled syringe. Research was also published to show the value of continuous blood pressure monitoring in dementia management. Astellas announced the acquisition of German pharmaceutical company Ganymed while Sunovion completed its purchase of Cynapsus. A new EU-funded collaboration was announced looking at the value of PET-based biomarkers in Alzheimer's disease. GSK gained USA approval for its shingles vaccine, but Novo Nordisk and Sanofi received complete response letters from the US FDA, requiring further information before regulatory review of their drug submissions can be completed. The UK's NICE concluded that a drug marketed by BMS to treat a common type of lung cancer was not cost-effective and Cornell University announced results showing that its nanoparticle technology, originally developed as a tumor biomarker, could be effective in directly treating the disease.

Third Pole Environment (TPE) -Latest Progress

NASA Astrophysics Data System (ADS)

Liu, Z.; Yao, T.; Zhang, F.; Yang, X.; Wang, W.; Ping, F.

2014-12-01

Centered on the Tibetan Plateau, the Third Pole region is a unique geographical unit, which represents one of the largest ice masses on the Earth. The region has great impacts on environmental changes in China, the Northern Hemisphere and the globe.It also demonstrates sensitive feedbacks to global changes and the impacts of anthropogenic activities in surrounding regions. Like the Arctic and Antarctica, the Third Pole region is an especially sensitive area that draws great attention from the scientific community. In 2009, with support from the Chinese Academy of Sciences and international organizations, the Third Pole Environment (TPE) program, led by Chinese scientists, was officially launched. The program focuses on the theme of "water-ice-air-ecosystem-human" interactions, with the aim to address the following scientific questions, such as the spatial and temporal characteristics of past environmental changes in the Third pole, the interactions between hydrosphere and cryosphere and hazard processes, the ecological systems' impacts on and response to environmental changes, and the impacts of anthropogenic activities on environmental changes in the region and adaptation strategies. The goal of the program is to reveal environmental change processes and mechanisms on the Third Pole and their influences on and responses to global changes, and thus to serve for enhancement of human adaptation to the changing environment and realization of human-nature harmony. Under the leadership of the co-chairs, and relying on Scientific Committee and the TPE office, the program has accomplished a number of scientific tasks since its inauguration. TPE has made tremendous progress in the research of glacier changes, interactions between the westerlies and monsoon, establishment of field stations, data sharing and education.

Latest developments in MUC1 immunotherapy.

PubMed

Taylor-Papadimitriou, Joyce; Burchell, Joy M; Graham, Rosalind; Beatson, Richard

2018-05-21

Currently, there is renewed interest in attempting to recruit the host immune system to eliminate cancers, and within this renewed activity, MUC1 continues to arouse interest. MUC1 has been considered a possible therapeutic target for the past 30 years as it is up-regulated, aberrantly glycosylated and its polarization is lost in many adenocarcinomas. Moreover, MUC1 is expressed by some haematopoietic cancers, including acute myeloid leukaemia and myeloma. Although multiple clinical trials have been initiated and immune responses have been documented, effective clinical benefit worthy of approval for general application has not as yet been achieved. However, this does not appear to have quelled the interest in MUC1 as a therapeutic target, as shown by the increase in the number of MUC1-based clinical trials initiated in 2017 ( Figure 1). As with all translational studies, incorporating new relevant research findings into therapeutic strategy is difficult. Decisions are made to commit to a specific strategy based on the information and data available when the trial is initiated. However, the time required for preclinical studies and early trials can render the founding concept not always appropriate for proceeding to a larger definitive trial. Here, we summarize the attempts made, to date, to bring MUC1 into the world of cancer immunotherapy and discuss how research findings regarding MUC1 structure and function together with expanded knowledge of its interactions with the tumour environment and immune effector cells could lead to improved therapeutic approaches. © 2018 The Author(s).

DoD Sustainability Strategy: The Latest...

DTIC Science & Technology

2011-05-01

Gas Emissions from Employee Air Travel Reduced 15% by FY 2020 Relative to FY 2011 • 30% of Eligible Employees Teleworking at Least Once a Week...Oct 2010  Telework DoD Instruction (DoDI) – Oct 2010  Sulfur Hexafluoride (SF6) Risk Management – Oct 2010  Integrated Solid Waste Management

Latest Trends in Home Networking Technologies

NASA Astrophysics Data System (ADS)

Tsutsui, Akihiro

Broadband access service, including FTTH, is now in widespread use in Japan. More than half of the households that have broadband Internet access construct local area networks (home networks) in their homes. In addition, information appliances such as personal computers, networked audio, and visual devices and game machines are connected to home networks, and many novel service applications are provided via the Internet. However, it is still difficult to install and incorporate these devices and services because networked devices have been developed in different communities. I briefly explain the current status of information appliances and home networking technologies and services and discuss some of the problems in this and their solutions.

Latest Developments in the Matrics Process

PubMed Central

Green, Michael Foster; Nuechterlein, Keith H

2010-01-01

The Measurement and Treatment Research to Improve Cognition in Schizophrenia Research process has led to several developments in the assessment of cognitive functioning for schizophrenia-treatment studies. The first development was the development of a consensus cognitive battery and a United States Food and Drug Administration-endorsed research design. Since the development of the cognitive battery, interest has been spurred in clinical trials in different countries and the development of co-primary functional outcomes measures for these. The MATRICS Consensus Cognitive Battery has been translated into 11 different languages and is being translated into even more. A study has been completed that compared the usefulness of multiple potential co-primary measures, suggesting that the University of California San Diego Performance-Based skills assessment, version II (UPSA-II) is the most suitable for studies conducted in English. These findings suggest that reliable performance-based measures that are easy to administer and highly correlated with cognitive functioning are now available for use in treatment studies. PMID:20622946

Portion Size: Latest Developments and Interventions.

PubMed

Steenhuis, Ingrid; Poelman, Maartje

2017-03-01

The aim of this review is to provide an overview of (1) underlying mechanisms of the effect of portion size on energy intake, (2) external factors explaining the portion size effect and (3) interventions and measurements aimed at food portion size. Previous studies have shown that portion sizes have increased in recent decades. Many experimental studies have been conducted to unravel the mechanisms underlying the portion-size effect on food intake (e.g. the appropriateness mechanism, the 'unit bias' mechanism, the 'previous experience/expectation' mechanism, the 'visual cue' mechanism and the 'bite size' mechanism). In addition, external factors have been found to drive food portion selection and consumption (e.g. value for money, mindless eating, levels of awareness, estimation bias. Research on several interventions (ranging from 'providing information' to 'eliminating choice') have been conducted, but remain scarce, especially intervention studies in which portion size is a key focus in weight loss. Moreover, only three new instruments with respect to portion control behavior have been developed. There is considerable evidence for the portion-size effect on energy intake. However, the work on interventions targeting portion size and measurements for portion control behavior are limited. Moreover, from the literature it is not yet clear what type of interventions work best, for whom and in what context.

[The latest in paediatric resuscitation recommendations].

PubMed

López-Herce, Jesús; Rodríguez, Antonio; Carrillo, Angel; de Lucas, Nieves; Calvo, Custodio; Civantos, Eva; Suárez, Eva; Pons, Sara; Manrique, Ignacio

2017-04-01

Cardiac arrest has a high mortality in children. To improve the performance of cardiopulmonary resuscitation, it is essential to disseminate the international recommendations and the training of health professionals and the general population in resuscitation. This article summarises the 2015 European Paediatric Cardiopulmonary Resuscitation recommendations, which are based on a review of the advances in cardiopulmonary resuscitation and consensus in the science and treatment by the International Council on Resuscitation. The Spanish Paediatric Cardiopulmonary Resuscitation recommendations, developed by the Spanish Group of Paediatric and Neonatal Resuscitation, are an adaptation of the European recommendations, and will be used for training health professionals and the general population in resuscitation. This article highlights the main changes from the previous 2010 recommendations on prevention of cardiac arrest, the diagnosis of cardiac arrest, basic life support, advanced life support and post-resuscitation care, as well as reviewing the algorithms of treatment of basic life support, obstruction of the airway and advanced life support. Copyright © 2016. Publicado por Elsevier España, S.L.U.

Foot osteoarthritis: latest evidence and developments

PubMed Central

Roddy, Edward; Menz, Hylton B.

2018-01-01

Foot osteoarthritis (OA) is a common problem in older adults yet is under-researched compared to knee or hand OA. Most existing studies focus on the first metatarsophalangeal joint, with evidence relating to midfoot OA being particularly sparse. Symptomatic radiographic foot OA affects 17% of adults aged 50 years and over. The first metatarsophalangeal joint is most commonly affected, followed by the second cuneometatarsal and talonavicular joints. Epidemiological studies suggest the existence of distinct first metatarsophalangeal joint and polyarticular phenotypes, which have differing clinical and risk factor profiles. There are few randomized controlled trials in foot OA. Existing trials provide some evidence of the effectiveness for pain relief of physical therapy, rocker-sole shoes, foot orthoses and surgical interventions in first metatarsophalangeal joint OA and prefabricated orthoses in midfoot OA. Prospective epidemiological studies and randomized trials are needed to establish the incidence, progression and prognosis of foot OA and determine the effectiveness of both commonly used and more novel interventions. PMID:29619094

Alternative Fuels Data Center: Latest Additions

Science.gov Websites

. May 2018 Foothill Transit Agency Battery Electric Bus Progress Report, Data Period Focus: Jan. 2017 Utility Vehicles Autonomy-Enabled Fuel Savings for Military Vehicles: Report on 2016 Aberdeen Test Center Report 2016 Survey of Non-Starch Alcohol and Renewable Hydrocarbon Biofuels Producers Ethanol Strong

Latest biomaterials and technology in dentistry.

PubMed

Zandparsa, Roya

2014-01-01

Navigation technology is applied successfully in oral and maxillofacial surgery. Laser beams are used for caries removal. With nanodentistry, it is possible to maintain comprehensive oral health care. Nanorobots induce oral analgesia, desensitize teeth, and manipulate the tissue. They can also be used for preventive, restorative, and curative procedures. Strategies to engineer tissue can be categorized into 3 major classes: conductive, inductive, and cell transplantation approaches. Several populations of cells with stem cell properties have been isolated from different parts of the tooth. Copyright © 2014 Elsevier Inc. All rights reserved.

Endoscopes with latest technology and concept.

PubMed

Gotoh

2003-09-01

Endoscopic imaging systems that perform as the "eye" of the operator during endoscopic surgical procedures have developed rapidly due to various technological developments. In addition, since the most recent turn of the century robotic surgery has increased its scope through the utilization of systems such as Intuitive Surgical's da Vinci System. To optimize the imaging required for precise robotic surgery, a unique endoscope has been developed, consisting of both a two dimensional (2D) image optical system for wider observation of the entire surgical field, and a three dimensional (3D) image optical system for observation of the more precise details at the operative site. Additionally, a "near infrared radiation" endoscopic system is under development to detect the sentinel lymph node more readily. Such progress in the area of endoscopic imaging is expected to enhance the surgical procedure from both the patient's and the surgeon's point of view.

Supplements in pregnancy: the latest recommendations

PubMed

Martínez García, Rosa María

2016-07-12

Pregnancy is a challenge from the nutritional point of view, because nutrient requirements are increased and alter its intake can affect maternal and fetal health. Micronutrient defi ciency states are related to preeclampsia, intrauterine growth restriction, abortion and congenital anomalies. Currently, the diet of many expectant mothers is insufficient in micronutrients, in this cases supplementation is necessary. It is recommended supplementation with folic acid in doses of 400 mcg / day and 5 mg/day in risk pregnant, and should begin at least one month before conception and during the first 12 weeks gestation, and extend it throughout pregnancy in mothers with nutritional risk. It is important to keep watch the proper dose of folic acid to prevent possible adverse effects of unmetabolized accumulation in plasma. A high percentage of pregnant women presented iron deficiency anemia, being recommended intermittent use of iron supplements (with lower gastrointestinal alteration and oxidative stress); not recommended for mothers without anemia (hemoglobin> 13.5 g / L). Since calcium absorption is increased up to 40% in gestation, its supplementation is not recommended for mothers with adequate intakes (3 dairy / day), and its use must be reserved to women with inadequate intakes and / or high risk of preeclampsia. Regarding the iodine, there are confl icting positions by different working groups established potassium iodide supplementation in women who do not reach their recommended intake (3 servings of milk and dairy products + 2 g of iodized salt), with their diets. Given that vitamin A and D can be toxic to mother and fetus, it is not recommended its supplementation except in cases of deficiency. Although the use of multiple micronutrients supplements may favorably impact the outcome of pregnancy, more scientific evidence is needed to establish the replacement of iron and folic acid with a multiple micronutrient supplement.

Latest Progress in High Power VECSELs

DTIC Science & Technology

2013-01-01

are more efficient, and can be tailored to an application. In this manuscript we lay out some advantages to VECSELs as compared to many in-plane...semiconductor lasers. We review common fabrication and packaging techniques in Section 2. In Section 3, we discuss both small- signal and large-signal... out LR coating MQW DBR VECSEL chip Heat Spreader output coupler HR flat mirror BF at Brewster’s angle HR flat mirror HR curved mirror signal beam out

Latest framework to improve vital signs.

PubMed

Baillie, Jonathan

2009-08-01

Greater consistency in NHS signage, coupled with the assurance of a high quality, competitively-priced range of signage and wayfinding products and services, are among the benefits promised to estates and facilities teams UK-wide following the NHS Purchasing and Supply Agency's (NHS PASA) recent launch of a new pan-Government signage framework agreement. Jonathan Baillie reports, and talks to several signage suppliers appointed to the framework about their expertise, skills and recent experience.

Dark Age Education: Our Latest Survey.

ERIC Educational Resources Information Center

Rosenthal, Joel

1981-01-01

Relates the history of ideas to the history of education during the middle ages. Topics discussed include cultural life, economic factors, the political economy of medieval education, and the difficulty of writing about educational trends during a time for which there are few authoritative sources. (DB)

Latest trends in craniomaxillofacial surgical instrumentation.

PubMed

Yim, Michael; Demke, Joshua

2012-08-01

To review the past year's literature regarding recent innovations in surgical instrumentation for craniomaxillofacial surgery. Current advances in surgical instrumentation have led to many improvements in the field, allowing greater visualization and precision both before and during procedures. One of the common goals is to achieve excellent outcomes with minimal complications, while at the same time minimizing invasiveness of surgery. Highlighted innovations include greater capacities for acquisition of data, leading to improved imaging modalities and expansion of computer-assisted surgical techniques; continued developments in biomaterials used in various reconstructions; and novel uses of bone cutting and bone fixation instrumentation. Technology in the field of craniomaxillofacial surgery is developing rapidly, leading to novel instrumentation being utilized across a broad spectrum of areas. Published data have been encouraging to date, indicating an ever increasing adaptation of these innovations in clinical practice. Future efforts need to focus on cost-benefit analysis and constructing larger-scale studies to better understand effectiveness and patient outcomes.

The Latest in Corporate-College Partnerships.

ERIC Educational Resources Information Center

Meister, Jeanne C.

2003-01-01

Success factors in establishing corporate-college partnerships include communicating a shared vision for success, defining the degree of customization and flexibility from a university, and mutually devising a marketing and recruitment program. The metrics for success must be defined early and managed throughout the partnership. (JOW)

Carbonate formation on Mars: Latest experiments

NASA Technical Reports Server (NTRS)

Stephens, S. K.; Stevenson, D. J.; Rossman, G. R.; Keyser, L. F.

1993-01-01

Laboratory simulations of Martian CO2 storage address whether carbonate formation could have reduced CO2 pressure from a hypothetical greater than 1 bar to the present 7 mbar in less than or equal to 3 to 4 billion years. This problem is addressed with experiments and analysis designed to verify and improve previous kinetic measurements, reaction mechanisms, and product characterizations, with the goal of improving existing models of Martian CO2 history. A sensitive manometer monitored the pressure drop of CO2 due to uptake by powdered silicate for periods of 3 to 100+ days. Pressure drops for diopside 1 and basalt show rapid short-term (approximately one day) CO2 uptake and considerably slower long-term pressure drops. Curves for diopside 2, olivine 1, and olivine 2 are qualitatively similar to those for diopside 1, whereas quartz and plagioclase show near-zero short-term pressure drops and very slow long-term signals, indistinguishable from a leak (less than 10(exp 11) mol/sq m/s).

The latest explosive eruptions of Ciomadul (Csomád) volcano, East Carpathians - A tephrostratigraphic approach for the 51-29 ka BP time interval

NASA Astrophysics Data System (ADS)

Karátson, D.; Wulf, S.; Veres, D.; Magyari, E. K.; Gertisser, R.; Timar-Gabor, A.; Novothny, Á.; Telbisz, T.; Szalai, Z.; Anechitei-Deacu, V.; Appelt, O.; Bormann, M.; Jánosi, Cs.; Hubay, K.; Schäbitz, F.

2016-06-01

The most recent, mainly explosive eruptions of Ciomadul, the youngest volcano in the Carpatho-Pannonian Region, have been constrained by detailed field volcanological studies, major element pumice glass geochemistry, luminescence and radiocarbon dating, and a critical evaluation of available geochronological data. These investigations were complemented by the first tephrostratigraphic studies of the lacustrine infill of Ciomadul's twin craters (St. Ana and Mohoş) that received tephra deposition during the last eruptions of the volcano. Our analysis shows that significant explosive activity, collectively called EPPA (Early Phreatomagmatic and Plinian Activity), started at Ciomadul in or around the present-day Mohoş, the older crater, at ≥ 51 ka BP. These eruptions resulted in a thick succession of pyroclastic-fall deposits found in both proximal and medial/distal localities around the volcano, characterized by highly silicic (rhyolitic) glass chemical compositions (ca. 75.2-79.8 wt.% SiO2). The EPPA stage was terminated by a subplinian/plinian eruption at ≥ 43 ka BP, producing pumiceous pyroclastic-fall and -flow deposits of similar glass composition, probably from a "Proto-St. Ana" vent located at or around the younger crater hosting the present-day Lake St. Ana. After a quiescent period with a proposed lava dome growth in the St. Ana crater, a new explosive stage began, defined as MPA (Middle Plinian Activity). In particular, a significant two-phase eruption occurred at 31.5 ka BP, producing pyroclastic flows from vulcanian explosions disrupting the preexisting lava dome of Sf. Ana, and followed by pumiceous fallout from a plinian eruption column. Related pyroclastic deposits show a characteristic, less evolved rhyolitic glass composition (ca. 70.2-74.5 wt.% SiO2) and occur both in proximal and medial/distal localities up to 21 km from source. The MPA eruptions, that may have pre-shaped a crater similar to, but possibly smaller than, the present-day St. Ana

Long-term outcome of the adjustable transobturator male system (ATOMS): results of a European multicentre study.

PubMed

Friedl, Alexander; Mühlstädt, Sandra; Zachoval, Roman; Giammò, Alessandro; Kivaranovic, Danijel; Rom, Maximilian; Fornara, Paolo; Brössner, Clemens

2017-05-01

To evaluate the long-term effectiveness and safety of the adjustable transobturator male system (ATOMS ® , Agency for Medical Innovations A.M.I., Feldkirch, Austria) in a European-wide multicentre setting. In all, 287 men with stress urinary incontinence (SUI) were treated with the ATOMS device between June 2009 and March 2016. Continence parameters (daily pad test/pad use), urodynamics (maximum urinary flow rate, voiding volume, residual urine), and pain/quality of life (QoL) ratings (visual analogue scale/Leeds Assessment of Neuropathic Symptoms and Signs, International Consultation on Incontinence Questionnaire-Short Form [ICIQ-SF]/Patient Global Impression of Improvement [PGI-I]) were compared preoperatively and after intermediate (12 months) as well as after individual maximum follow-up. Overall success rate, dry rate (<10 mL/day and 0-1 pad/day), device durability, treatment failure, and device complications were recorded. Nonparametric tests were used for statistical analyses. After a median (interquartile range [IQR]) follow-up of 31 (10-54) months and a median (IQR) of 3 (2-4) adjustments, the overall success rate was 90% (258 men) and the dry rate was 64% (184). Daily pad test and pad use decreased from a median of 400 mL/day and 4 pads/day to a median of 18 mL/day and 1 pad/day (both P < 0.001), concomitantly QoL ratings significantly improved and changed to a high level of satisfaction (PGI-I 4 to 2, ICIQ-SF 17 to 5; both P < 0.001). The UI results at 12 months were comparable to those at final follow-up. Chronic pain and intraoperative complications did not occur. Most of the postoperative complications were Clavien-Dindo grade I-III (no grade IV or V). At present, 231 (80%) of all the ATOMS devices are still functioning; 56 (20%) were removed, the most common reason being local titanium intolerance (41%) and leak/dysfunction (30%). The operating time and continence outcome varied between port generations. In this regard the latest port generation

Complete tylosis formation in a latest Permian conifer stem

PubMed Central

Feng, Zhuo; Wang, Jun; Rößler, Ronny; Kerp, Hans; Wei, Hai-Bo

2013-01-01

Background and Aims Our knowledge of tylosis formation is mainly based on observations of extant plants; however, its developmental and functional significance are less well understood in fossil plants. This study, for the first time, describes a complete tylosis formation in a fossil woody conifer and discusses its ecophysiological implications. Methods The permineralized stem of Shenoxylon mirabile was collected from the upper Permian (Changhsingian) Sunjiagou Formation of Shitanjing coalfield, northern China. Samples from different portions of the stem were prepared by using the standard thin-sectioning technique and studied in transmitted light. Key Results The outgrowth of ray parenchyma cells protruded into adjacent tracheids through pits initially forming small pyriform or balloon-shaped structures, which became globular or slightly elongated when they reached their maximum size. The tracheid luminae were gradually occluded by densely spaced tyloses. The host tracheids are arranged in distinct concentric zones representing different growth phases of tylosis formation within a single growth ring. Conclusions The extensive development of tyloses from the innermost heartwood (metaxylem) tracheids to the outermost sapwood tracheids suggests that the plant was highly vulnerable and reacted strongly to environmental stress. Based on the evidence available, the tyloses were probably not produced in response to wound reaction or pathogenic infection, since evidence of wood traumatic events or fungal invasion are not recognizable. Rather, they may represent an ecophysiological response to the constant environmental stimuli. PMID:23532049

Clinical and scientific results in perinatal care of pregnancy complicated by insulin dependent diabetes mellitus in Croatia.

PubMed

Djelmis, J

1998-01-01

At the Department of Obstetrics and Gynecology, Perinatal Unit for Diabetes and Fetal Growth, School of Medicine, Zagreb, perinatal care of pregnancies complicated with insulin dependent diabetes melitus (IDDM), has been performed for more than 36 years. The intention of this review is to show our own results in the management of IDDM pregnancies and the latest clinical advances in perinatal care of such pregnancies. Pregnancy complicated with IDDM is at risk because of numerous maternal, fetal and neonatal complications. Recent advances in medicine, especially in diabetology and perinatology, helps clinician avoid or lessen antenatal or perinatal complications in IDDM pregnancies. The main result of improved perinatal care is that today fetal and neonatal mortality in IDDM pregnancy is almost equal to that of healthy pregnant population. Intensive preconceptual care and optimal regulation of IDDM have resulted not only in decreased perinatal mortality but also in a decreased rate of congenital malformation. Tight glycemia control during pregnancy has a beneficial effect on fetal growth. Intensive control of fetal growth, verification of lung maturation at term by amniocenthesis, and control of fetal oxygenation will result in delivery of a mature eutrophic newborn with the lowest rate of neonatal complications possible. Perinatal mortality of less than 2% in IDDM pregnancy can be obtained by planned delivery between 38 and 39 weeks of gestation by either vaginal route or cesarean section, depending on indications. After delivery, intensive care of the newborn is necessary.

Small Theropod Teeth from the Late Cretaceous of the San Juan Basin, Northwestern New Mexico and Their Implications for Understanding Latest Cretaceous Dinosaur Evolution

PubMed Central

Williamson, Thomas E.; Brusatte, Stephen L.

2014-01-01

Studying the evolution and biogeographic distribution of dinosaurs during the latest Cretaceous is critical for better understanding the end-Cretaceous extinction event that killed off all non-avian dinosaurs. Western North America contains among the best records of Late Cretaceous terrestrial vertebrates in the world, but is biased against small-bodied dinosaurs. Isolated teeth are the primary evidence for understanding the diversity and evolution of small-bodied theropod dinosaurs during the Late Cretaceous, but few such specimens have been well documented from outside of the northern Rockies, making it difficult to assess Late Cretaceous dinosaur diversity and biogeographic patterns. We describe small theropod teeth from the San Juan Basin of northwestern New Mexico. These specimens were collected from strata spanning Santonian – Maastrichtian. We grouped isolated theropod teeth into several morphotypes, which we assigned to higher-level theropod clades based on possession of phylogenetic synapomorphies. We then used principal components analysis and discriminant function analyses to gauge whether the San Juan Basin teeth overlap with, or are quantitatively distinct from, similar tooth morphotypes from other geographic areas. The San Juan Basin contains a diverse record of small theropods. Late Campanian assemblages differ from approximately co-eval assemblages of the northern Rockies in being less diverse with only rare representatives of troodontids and a Dromaeosaurus-like taxon. We also provide evidence that erect and recurved morphs of a Richardoestesia-like taxon represent a single heterodont species. A late Maastrichtian assemblage is dominated by a distinct troodontid. The differences between northern and southern faunas based on isolated theropod teeth provide evidence for provinciality in the late Campanian and the late Maastrichtian of North America. However, there is no indication that major components of small-bodied theropod diversity were lost

Small theropod teeth from the Late Cretaceous of the San Juan Basin, northwestern New Mexico and their implications for understanding latest Cretaceous dinosaur evolution.

PubMed

Williamson, Thomas E; Brusatte, Stephen L

2014-01-01

Studying the evolution and biogeographic distribution of dinosaurs during the latest Cretaceous is critical for better understanding the end-Cretaceous extinction event that killed off all non-avian dinosaurs. Western North America contains among the best records of Late Cretaceous terrestrial vertebrates in the world, but is biased against small-bodied dinosaurs. Isolated teeth are the primary evidence for understanding the diversity and evolution of small-bodied theropod dinosaurs during the Late Cretaceous, but few such specimens have been well documented from outside of the northern Rockies, making it difficult to assess Late Cretaceous dinosaur diversity and biogeographic patterns. We describe small theropod teeth from the San Juan Basin of northwestern New Mexico. These specimens were collected from strata spanning Santonian - Maastrichtian. We grouped isolated theropod teeth into several morphotypes, which we assigned to higher-level theropod clades based on possession of phylogenetic synapomorphies. We then used principal components analysis and discriminant function analyses to gauge whether the San Juan Basin teeth overlap with, or are quantitatively distinct from, similar tooth morphotypes from other geographic areas. The San Juan Basin contains a diverse record of small theropods. Late Campanian assemblages differ from approximately coeval assemblages of the northern Rockies in being less diverse with only rare representatives of troodontids and a Dromaeosaurus-like taxon. We also provide evidence that erect and recurved morphs of a Richardoestesia-like taxon represent a single heterodont species. A late Maastrichtian assemblage is dominated by a distinct troodontid. The differences between northern and southern faunas based on isolated theropod teeth provide evidence for provinciality in the late Campanian and the late Maastrichtian of North America. However, there is no indication that major components of small-bodied theropod diversity were lost

THAO-CHILD HEALTH PROGRAMME: COMMUNITY BASED INTERVENTION FOR HEALTHY LIFESTYLES PROMOTION TO CHILDREN AND FAMILIES: RESULTS OF A COHORT STUDY.

PubMed

Gómez Santos, Santiago Felipe; Estévez Santiago, Rocío; Palacios Gil-Antuñano, Nieves; Leis Trabazo, Maria Rosaura; Tojo Sierra, Rafael; Cuadrado Vives, Carmen; Beltrán de Miguel, Beatriz; Ávila Torres, José Manuel; Varela Moreiras, Gregorio; Casas Esteve, Rafael

2015-12-01

childhood obesity is one of the main public health concerns. The multifactorial and multilevel causes require complex interventions such the community based interventions (CBI). Thao-Child Health Programme is a CBI implemented in Spain since 2007. show the Thao methodology and the latest cross-sectional and longitudinal results. longitudinal cohort study (4 years of follow- up) and cross sectional study. the longitudinal study found an increase of 1% in the overweight prevalence after a follow-up of 4 years of Thao-Programme implementation in 10 municipalities with 6 697 children involved. The cross-sectional study carried out with 20 636 children from 22 municipalities found a childhood overweight prevalence of 26.6%. currently a brake in the increase of childhood overweight prevalence is considered a success due to the high prevalence worldwide. More studies well methodologically performed are needed to know the efficacy of the CBI's in this field. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

Mapping Antarctica using Landsat-8 - the preliminary results

NASA Astrophysics Data System (ADS)

Cheng, X.; Hui, F.; Qi, X.

2014-12-01

The first Landsat Image Mosaic of Antarctica (LIMA) was released in 2009, which was created by USGS, BAS, and NASA from more than 1,000 Landsat ETM+ scenes. As the first major scientific outcome of the IPY, LIMA supports current scientific polar research, encourages new projects, and helps the general public visualize Antarctica and changes happening to this southernmost environment. As the latest satellite of Landsat mission, the Landsat-8 images the entire Earth every 16 days in an 8-day offset from Landsat-7. Data collected by the instruments onboard the satellite are available to download at no charge within 24 hours of reception. The standard Landsat 8 products provided by the USGS EROS Center consist of quantized and calibrated scaled Digital Numbers (DN) in 16-bit unsigned integer format and can be rescaled to the Top Of Atmosphere (TOA) reflectance and/or radiance. With the support of USGS portal, we searched and downloaded more than 1600 scenes of Level 1 T- Terrain Corrected Landsat 8 image products covering Antarctica from late 2013 to early 2014. These data were converted to planetary radiance for further processing. Since the distribution of clouds in these images are random and much complicated, statistics on the distribution of clouds were performed and then help to decide masking those thicker cloud to keep more useful information left and avoid observation holes. A preliminary result of the Landsat-8 mosaic of Antarctica under the joint efforts of Beijing Normal University, NSIDC and University of Maryland will be released on this AGU fall meeting. Comparison between Landsat 7 and 8 mosaic products will also be done to find the difference or advantage of the two products.

Latest developments in a multi-user 3D display

NASA Astrophysics Data System (ADS)

Surman, Phil; Sexton, Ian; Bates, Richard; Lee, Wing Kai; Hopf, Klaus; Koukoulas, Triantaffilos

2005-11-01

De Montfort University, in conjunction with the Heinrich Hertz Institute, is developing a 3D display that is targeted specifically at the television market. It is capable of supplying 3D to several viewers who do not have to wear special glasses, and who are able to move freely over a room-sized area. The display consists of a single liquid crystal display that presents the same stereo pair to every viewer by employing spatial multiplexing. This presents a stereo pair on alternate pixel rows, with the conventional backlight replaced by novel steering optics controlled by the output of a head position tracker. Illumination is achieved using arrays of coaxial optical elements in conjunction with high-density white light emitting diode arrays. The operation of the steering and multiplexing optics in the prototype display are explained. The results obtained from a prototype built under the European Union-funded ATTEST 3D television project are described. The performance of this model was not optimum, but was sufficient to prove that the principle of operation is viable for a 3D television display. A second prototype, incorporating improvements based on experience gained, is currently under construction and this is also described. The prototype is capable of being developed into a display appropriate for a production model that will enable 3D television to come to market within the next ten years. With the current widespread usage of flat panel displays it is likely that customer preference will be for a hang-on-the-wall 3D display, and this challenge will be met by reconfiguring the optics and incorporating novel optical addressing techniques.

Regretting Ever Starting to Smoke: Results from a 2014 National Survey.

PubMed

Nayak, Pratibha; Pechacek, Terry F; Slovic, Paul; Eriksen, Michael P

2017-04-06

Background : The majority of smokers regret ever starting to smoke, yet the vast majority continue to smoke despite the fact that smoking kills nearly 50% of lifetime users. This study examined the relationships between regret and smoker characteristics, quit history, risk perceptions, experiential thinking, and beliefs and intentions at time of smoking initiation. Methods : Data from the 2014 Tobacco Products and Risk Perceptions Survey, a nationally representative survey of United States adults, were analyzed to provide the latest prevalence estimates of regret and potential predictors. Relationships among predictor variables and regret were analyzed using correlations, t -tests, and multinomial logistic regression. Results : The majority of smokers (71.5%) regretted starting to smoke. Being older and non-Hispanic white were significant predictors of regret. Smokers having a high intention to quit, having made quit attempts in the past year, worrying about getting lung cancer, believing smoking every day can be risky for your health, perceiving a risk of being diagnosed with lung cancer during one's lifetime, and considering themselves addicted to cigarettes were significant predictors of regret for smoking initiation. Conclusions : This study provides updated prevalence data on regret using a national sample, and confirms that regret is associated with perceived risk. The findings from this study can be used to inform smoking intervention programs and support the inclusion of smoker regret in cost-benefit analyses of the economic impact of tobacco regulations.

The 1979 Goddard Space Flight Center Battery Workshop

NASA Technical Reports Server (NTRS)

Halpert, G. (Editor)

1980-01-01

Papers discussing the latest results of testing, analysis, and development of the sealed nickel cadmium cell system are presented. Metal hydrogen and lithium cell technology and applications are also discussed. The purpose of the workshop was to share flight and test experience, stimulate discussion on problem areas, and to review the latest technology improvements.

Latest developments on the Dutch 1MW free electron maser

NASA Astrophysics Data System (ADS)

Caplan, M.; Verhoeven, A. G. A.; Urbanus, W.

1999-05-01

The FOM Institute (Rijnhuizen, Netherlands), as part of their fusion technology program, has undertaken the development of a Free Electron Maser with the goal of producing 1MW long pulse to CW microwave output in the range 130 GHz-250GHz with wall plug efficiencies of 60%. This project has been carried out as a collaborative effort with Institute of Applied Physics, Nizhny Novgorod Russia, Kurchatov Institute, Moscow Russia, Lawrence Livermore Laboratory, U.S.A and CPI, U.S.A. The key design features of this FEM consists first of a conventional DC acceleration system at high voltage (2MV) which supplies only the unwanted beam interception current and a depressed collector system at 250kV which provides the main beam power. Low body current interception (<25mA) is ensured by using robust inline beam focussing, a low emittance electron gun with halo suppression and periodic magnet side array focussing in the wiggler. The second key feature is use of a low-loss step corrugated waveguide circuit for broad band CW power handling and beam/RF separation. Finally, the required interaction efficiency and mode control is provided by a two stage stepped wiggler. The FEM has been constructed and recently undergone initial short pulse (<10 usec) testing in an inverted mode with the depressed collector absent. Results to date have demonstrated 98.8% beam transmission (over 5 Meters) at currents as high as 8.4 Amps, with 200GHz microwave output at 700kW. There has been good agreement between theory and experiment at the beam current levels tested so far. Details of the most recent experimental results will be presented, in particular the output frequency characteristics with detailed comparisons to theory. The immediate future plans are to operate the system at the design value of 12 Amps with at least 1MW output. The system will then be reconfigured with a 3 stage depressed collector to demonstrate, in the next year, long pulse operation (100 msec) and high wall plug efficiency

Evaluation of CALGRID using two different ozone episodes and comparison to UAM results

NASA Astrophysics Data System (ADS)

Kumar, Naresh; Russell, Armistead G.; Tesche, Thomas W.; McNally, Dennis E.

Air quality models serve as the foundation for policy decisions regarding programs designed to improve air quality. The California Air Resources Board Airshed Model (CALGRID) is one of the latest photochemical air quality models developed for assessing ozone control strategies. CALGRID was modified to include the lates CBIV chemical mechanism in place of the original SAPRC mechanism. After modification, a detailed evaluation of CALGRID was carried out using two different ozone episodes. The first evaluation used data obtained during the Southern California Air Quality Study (SCAQS). The second evaluation used data obtained for the September, 1984 SCCCAMP episodes in the South Central Coast Air Basin (SCCAB). Model results were compared against observations of O 3, NO, NO 2, and different organic compounds. For the SCCAB episode, the results were also compared with those obtained from the Urban Airshed Model (UAM). Similar to other studies, the ozone predictions from the SCAQS application were biased low, as were various ROG components. The reason for this can be linked to the under-representation of ROG and CO in the emissions inventory. For the SCCAB episode, both the UAM and CALGRID models significantly underestimated NO and NO 2 concentrations. The two models slightly underestimated ozone concentrations above approximately 9 pphm on the third and last day of the simulation. Sensitivity experiments were performed for both the studies. It was found that both CALGRID and UAM are strongly sensitive to the boundary conditions and moderately sensitive to the emissions for the episodes modeled.

Differential cross-sections measurements for hadrontherapy: 50 MeV/A 12C reactions on H, C, O, Al and natTi targets

NASA Astrophysics Data System (ADS)

Divay, C.; Colin, J.; Cussol, D.; Finck, Ch.; Karakaya, Y.; Labalme, M.; Rousseau, M.; Salvador, S.; Vanstalle, M.

2017-09-01

In order to keep the benefits of a carbon treatment, the dose and biological effects induced by secondary fragments must be taken into account when simulating the treatment plan. These Monte-Carlo simulations codes are done using nuclear models that are constrained by experimental data. It is hence necessary to have precise measurements of the production rates of these fragments all along the beam path and for its whole energy range. In this context, a series of experiments aiming to measure the double differential fragmentation cross-sections of carbon on thin targets of medical interest has been started by our collaboration. In March 2015, an experiment was performed with a 50 MeV/nucleon 12C beam at GANIL. During this experiment, energy and angular differential cross-section distributions on H, C, O, Al and natTi have been measured. In the following, the experimental set-up and analysis process are briefly described and some experimental results are presented. Comparisons between several exit channel models from Phits and Geant4 show great discrepancies with the experimental data. Finally, the homemade Sliipie model is briefly presented and preliminary results are compared to the data with a promising outcome.

Testing the white dwarf mass-radius relation and comparing optical and far-UV spectroscopic results with Gaia DR2, HST and FUSE

NASA Astrophysics Data System (ADS)

Joyce, S. R. G.; Barstow, M. A.; Casewell, S. L.; Burleigh, M. R.; Holberg, J. B.; Bond, H. E.

2018-05-01

Observational tests of the white dwarf mass-radius relationship have always been limited by the uncertainty in the available distance measurements. Most studies have focused on Balmer line spectroscopy because these spectra can be obtained from ground based observatories, while the Lyman lines are only accessible to space based UV telescopes. We present results using parallax data from Gaia DR2 combined with space based spectroscopy from HST and FUSE covering the Balmer and Lyman lines. We find that our sample supports the theoretical relation, although there is at least one star which is shown to be inconsistent. Comparison of results between Balmer and Lyman line spectra shows they are in agreement when the latest broadening tables are used. We also assess the factors which contribute to the error in the mass-radius calculations and confirm the findings of other studies which show that the spread in results for targets where multiple spectra are available is larger than the statistical error. The uncertainty in the spectroscopically derived log g parameter is now the main source of error rather than the parallax. Finally, we present new results for the radius and spectroscopic mass of Sirius B which agree with the dynamical mass and mass-radius relation within 1σ.

Physico-chemical properties of aqueous drug solutions: From the basic thermodynamics to the advanced experimental and simulation results.

PubMed

Bellich, Barbara; Gamini, Amelia; Brady, John W; Cesàro, Attilio

2018-04-05

The physical chemical properties of aqueous solutions of model compounds are illustrated in relation to hydration and solubility issues by using three perspectives: thermodynamic, spectroscopic and molecular dynamics simulations. The thermodynamic survey of the fundamental backgrounds of concentration dependence and experimental solubility results show some peculiar behavior of aqueous solutions with several types of similar solutes. Secondly, the use of a variety of experimental spectroscopic devices, operating under different experimental conditions of dimension and frequency, has produced a large amount of structural and dynamic data on aqueous solutions showing the richness of the information produced, depending on where and how the experiment is carried out. Finally, the use of molecular dynamics computational work is presented to highlight how the different types of solute functional groups and surface topologies organize adjacent water molecules differently. The highly valuable contribution of computer simulation studies in providing molecular explanations for experimental deductions, either of a thermodynamic or spectroscopic nature, is shown to have changed the current knowledge of many aqueous solution processes. While this paper is intended to provide a collective view on the latest literature results, still the presentation aims at a tutorial explanation of the potentials of the three methodologies in the field of aqueous solutions of pharmaceutical molecules. Copyright © 2018. Published by Elsevier B.V.

On the use of Empirical Data to Downscale Non-scientific Scepticism About Results From Complex Physical Based Models

NASA Astrophysics Data System (ADS)

Germer, S.; Bens, O.; Hüttl, R. F.

2008-12-01

The scepticism of non-scientific local stakeholders about results from complex physical based models is a major problem concerning the development and implementation of local climate change adaptation measures. This scepticism originates from the high complexity of such models. Local stakeholders perceive complex models as black-box models, as it is impossible to gasp all underlying assumptions and mathematically formulated processes at a glance. The use of physical based models is, however, indispensible to study complex underlying processes and to predict future environmental changes. The increase of climate change adaptation efforts following the release of the latest IPCC report indicates that the communication of facts about what has already changed is an appropriate tool to trigger climate change adaptation. Therefore we suggest increasing the practice of empirical data analysis in addition to modelling efforts. The analysis of time series can generate results that are easier to comprehend for non-scientific stakeholders. Temporal trends and seasonal patterns of selected hydrological parameters (precipitation, evapotranspiration, groundwater levels and river discharge) can be identified and the dependence of trends and seasonal patters to land use, topography and soil type can be highlighted. A discussion about lag times between the hydrological parameters can increase the awareness of local stakeholders for delayed environment responses.

Changes in calcareous nannoplankton calcification during the latest Cenomanian Oceanic Anoxic Event 2 and similarity with other Cretaceous Oceanic Anoxic Events

NASA Astrophysics Data System (ADS)

Faucher, Giulia; Erba, Elisabetta; Bottini, Cinzia

2016-04-01

The Cenomanian has been characterized by greenhouse climate conditions and profound environmental perturbations, including the latest Cenomanian Oceanic Anoxic Event 2 (OAE 2), an episode of widespread organic matter burial in oxygen-depleted oceans. OAE 2 is thought to be related to the emplacement of the Caribbean Plateau which probably introduced in the atmosphere a large amount of CO2 with consequent impact on biota, climate and ocean chemistry. The perturbation of the carbon cycle is reflected in the carbon isotopic record that evidences a positive shift at the OAE 2 onset and subsequent C-isotopic peaks. The aim of this study is the identification of possible changes in coccolith size/shape as a response to paleoenvironmental perturbations associated with OAE 2. Biometric analyses were performed on selected coccolith species (Biscutum constans, Discorhabdus rotatorius, Watznaueria barnesiae and Zeugrabdothus erectus) from five sections spanning the Cenomanian-Turonian boundary interval including OAE 2. The study provided evidence for size fluctuations and dwarfism of B. constans, Z. erectus and D. rotatorius during OAE 2, followed by a recovery at the end of the event. On the contrary, W. barnesiae displays constant sizes through the event. High-resolution investigations showed that B. constans follows the same size trends in all the analysed sections with i) a decrease in size at the OAE 2 onset where an increase in pCO2 is observed, ii) a partial increase in size back to pre-OAE 2 values around the first δ13C peak (peak A), where a decrease in pCO2 concentration is reconstructed iii) and a subsequent more expressed decrease in size reaching minimum values around the δ13C peak B where trace metal abundance has been identified. Small specimens are present till the end of OAE 2 and only after δ13C peak D a partial recovery in size is observed. Nannoplankton dwarfism is here interpreted as forced by rapidly increasing pCO2 during the formation of the

Paul Trapping of Radioactive {sup 6}He{sup +} Ions and Direct Observation of Their {beta} Decay

DOE Office of Scientific and Technical Information (OSTI.GOV)

Flechard, X.; Lienard, E.; Mery, A.

2008-11-21

We demonstrate that abundant quantities of short-lived {beta} unstable ions can be trapped in a novel transparent Paul trap and that their decay products can directly be detected in coincidence. Low energy {sup 6}He{sup +} (807 ms half-life) ions were extracted from the SPIRAL source at GANIL, then decelerated, cooled, and bunched by means of the buffer gas cooling technique. More than 10{sup 8} ions have been stored over a measuring period of six days, and about 10{sup 5} decay coincidences between the beta particles and the {sup 6}Li{sup ++} recoiling ions have been recorded. The technique can be extendedmore » to other short-lived species, opening new possibilities for trap assisted decay experiments.« less

Fission fragment yields from heavy-ion-induced reactions measured with a fragment separator

NASA Astrophysics Data System (ADS)

Tarasov, O. B.; Delaune, O.; Farget, F.; Morrissey, D. J.; Amthor, A. M.; Bastin, B.; Bazin, D.; Blank, B.; Cacéres, L.; Chbihi, A.; Fernández-Dominguez, B.; Grévy, S.; Kamalou, O.; Lukyanov, S. M.; Mittig, W.; Pereira, J.; Perrot, L.; Saint-Laurent, M.-G.; Savajols, H.; Sherrill, B. M.; Stodel, C.; Thomas, J. C.; Villari, A. C.

2018-04-01

The systematic study of fission fragment yields under different initial conditions has provided valuable experimental data for benchmarking models of fission product yields. Nuclear reactions using inverse kinematics coupled to the use of a high-resolution spectrometer with good fragment identification are shown here to be a powerful tool to measure the inclusive isotopic yields of fission fragments. In-flight fusion-fission was used in this work to produce secondary beams of neutron-rich isotopes in the collisions of a 238U beam at 24 MeV/u with 9Be and 12C targets at GANIL using the LISE3 fragment separator. Unique identification of the A, Z, and atomic charge state, q, of fission products was attained with the Δ E- TKE-B ρ- ToF measurement technique. Mass, and atomic number distributions are reported for the two reactions. The results show the importance of different reaction mechanisms in the two cases. The optimal target material for higher yields of neutron-rich high- Z isotopes produced in fusion-fission reactions as a function of projectile energy is discussed.

SPIRAL2 at Ganil:. a World Leading Isol Facility for the Physics of Exotic Nuclei

NASA Astrophysics Data System (ADS)

Gales, S.

2008-04-01

During the last two decades, RIB has allowed the investigation of a new territory of nuclei with extreme N/Z called "terra incognita". Due to technical limitations, existing facilities were able to cover some part of the light mass region of this "terra incognita". The main goal of SPIRAL2 is clearly to extend our knowledge of the limit of existence and the structure of nuclei deeply in the medium and heavy mass region (A = 60 to 140) which is to day an almost unexplored continent. SPIRAL 2 is based on a high power, CW, superconducting driver LINAC, delivering 5 mA of deuteron beams at 40MeV (200KW) directed on a C converter+ Uranium target and producing therefore more 1013 fissions/s. The expected radioactive beams intensities for exotic species in the mass range from A = 60 to A = 140, of the order of 106 to 1010pps will surpass by two order of magnitude any existing facilities in the world. These unstable atoms will be available at energies between few KeV/n to 15 MeV/n. The same driver will accelerate high intensity (100μA to 1 mA), heavier ions up to Ar at 14 MeV/n producing also proton rich exotic nuclei. In applied areas SPIRAL2 is considered as a powerful variable energy neutron source, a must to study the impact of nuclear fission and fusion on materials. The intensities of these unstable species are excellent opportunities for new tracers and diagnostics either for solid state, material or for radiobiological science and medicine. The "Go" decision has been taken in May 2005. The investments and personnel costs amount to 190 M€, for the construction period 2006-2012. The project group has been completed in 2006, the construction of the accelerator started in the beginning of 2007 whereas detail design of the RIB production processes are underway. Construction of the SPIRAL2 facility is shared by ten French laboratories and a network of international partners. Under the 7FP program of European Union called "Preparatory phase for the construction of new facilities", the SPIRAL2 project has been granted a budget of about 4M€ to build up an international consortium around this new venture. Regarding the future physics program a call for Letter of intents has been launched in Oct 2006. A very positive and enthusiastic response is the basis of new large international collaborations. Proposals for innovative new instrumentation and methods for the for SPIRAL2 facility are being examined by an International. Scientific Advisory Committee. The status of the construction of SPIRAL2 accelerator and technical R&D programs for physics instrumentation (detectors, spectrometers) in collaboration with EU and International partners will be presented.

Latest Pannonian and Quaternary evolution at the transition between Eastern Alps and Pannonian Basin: new insights from geophysical, sedimentological and geochronological data

NASA Astrophysics Data System (ADS)

Zámolyi, A.; Salcher, B.; Draganits, E.; Exner, U.; Wagreich, M.; Gier, S.; Fiebig, M.; Lomax, J.; Surányi, G.; Diel, M.; Zámolyi, F.

2017-07-01

The transition zone between Eastern Alps and Pannonian Basin is a key area for the investigation of the interplay between regional uplift, local tectonic subsidence and depositional environment. Our study area, the western margin of the Little Hungarian Plain, is characterized by gentle hills, plateaus and depressions, of which several are filled by lakes—including one of Austria's largest and shallowest lakes, Lake Neusiedl. Geological investigation is hampered by the scarcity of outcrops, and thus direct observation of sedimentological or structural features is difficult. Despite a long research history in the area, a consistent landscape evolution model considering all relevant constraints is lacking so far. In this study, we apply multidisciplinary methods to decipher the complex tectonic and fluvial depositional evolution of the region. Local data from shallow-lake drilling and seismic investigation are combined with regional data from industrial seismics and core data to gain new insights into the latest Pannonian (Late Miocene) and Quaternary evolution. Shallow-lake seismic data show the erosionally truncated Pannonian sediments dipping and thickening toward southeast, toward the modern depocenter of the Little Hungarian Plain. Overlying Quaternary fluvial sediments show a very similar thickening trend except for the area on the plateau north of the lake indicating ongoing subsidence in major parts of the basin. Drill cores from locations along the lake seismic lines were analyzed concerning their age, mineralogy and heavy minerals and compared with outcrop samples from the surrounding plains and the plateau to derive indications on sediment provenance. A key observation is the apparent lack of a significant gravel layer on top of the tilted Pannonian sediments beneath Lake Neusiedl. Small-scale faults can be observed in the lake seismic sections along with key sedimentary features. Significant differences of the current elevation of the top Pannonian

Latest Rate, Extent, and Temporal Evolution of Growth Faulting over Greater Houston Region Revealed by Multi- Band InSAR Time-Series Analysis

NASA Astrophysics Data System (ADS)

Qu, F.; Lu, Z.; Kim, J. W.

2017-12-01

Growth faults are common and continue to evolve throughout the unconsolidated sediments of Greater Houston (GH) region in Texas. Presence of faults can induce localized surface displacements, aggravate localized subsidence, and discontinue the integrity of ground water flow. Property damages due to fault creep have become more evident during the past few years over the GH area, portraying the necessity of further study of these faults. Interferometric synthetic aperture radar (InSAR) has been proven to be effective in mapping creep along and/or across faults. However, extracting a short wavelength, as well as small amplitude of the creep signal (about 10-20 mm/year) from long time span interferograms is extremely difficult, especially in agricultural or vegetated areas. This paper aims to map and monitor the latest rate, extent, and temporal evolution of faulting at a highest spatial density over GH region using an improved Multi-temporal InSAR (MTI) technique. The method, with maximized usable signal and correlation, has the ability to identify and monitor the active faults to provide an accurate and elaborate image of the faults. In this study, two neighboring ALOS tracks and Sentinel-1A datasets are used. Many zones of steep phase gradients and/or discontinuities have been recognized from the long term velocity maps by both ALOS (2007-2011) and Sentinei-1A (2015-2017) imagery. Not only those previously known faults position but also the new fault traces that have not been mapped by other techniques are imaged by our MTI technique. Fault damage and visible cracking of ground were evident at most locations through our field survey. The discovery of new fault activation, or faults moved from earlier locations is a part of the Big Barn Fault and Conroe fault system, trending from southwest to northeast between Hockley and Conroe. The location of area of subsidence over GH is also shrinking and migrating toward the northeast (Montgomery County) after 2000. The

Numerical modelling of river morphodynamics: Latest developments and remaining challenges

NASA Astrophysics Data System (ADS)

Siviglia, Annunziato; Crosato, Alessandra

2016-07-01

Numerical morphodynamic models provide scientific frameworks for advancing our understanding of river systems. The research on involved topics is an important and socially relevant undertaking regarding our environment. Nowadays numerical models are used for different purposes, from answering questions about basic morphodynamic research to managing complex river engineering problems. Due to increasing computer power and the development of advanced numerical techniques, morphodynamic models are now more and more used to predict the bed patterns evolution to a broad spectrum of spatial and temporal scales. The development and the success of application of such models are based upon a wide range of disciplines from applied mathematics for the numerical solution of the equations to geomorphology for the physical interpretation of the results. In this light we organized this special issue (SI) soliciting multidisciplinary contributions which encompass any aspect needed for the development and applications of such models. Most of the papers in the SI stem from contributions to session HS9.5/GM7.11 on numerical modelling and experiments in river morphodynamics at the European Geosciences Union (EGU) General Assembly held in Vienna, April 27th to May 2nd 2014.

Photonic liquid crystal fibers — a new challenge for fiber optics and liquid crystals photonics

NASA Astrophysics Data System (ADS)

Woliński, T. R.; Ertman, S.; Lesiak, P.; Domański, A. W.; Czapla, A.; Dąbrowski, R.; Nowinowski-Kruszelnicki, E.; Wójcik, J.

2006-12-01

The paper reviews and discusses the latest developments in the field of the photonic liquid crystal fibers that have occurred for the last three years in view of new challenges for both fiber optics and liquid crystal photonics. In particular, we present the latest experimental results on electrically induced birefringence in photonic liquid crystal fibers and discuss possibilities and directions of future developments.

Postirradiation analysis of the latest high uranium density miniplate test: RERTR 8.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hofman, G. L.; Kim, Y. S.; Rest, J.

2008-01-01

Results of destructive examination of fuel miniplates irradiated in the RERTR-8 test are discussed. Metallographic features of dispersion fuel containing fuel particles of U-7wt%Mo with 1wt% Ti or 2wt% Zr are analyzed. It is hypothesized that Zr, either as alloy addition or fission product, may have a destabilizing effect on fission gas behavior. The purpose of miniplate test RERTR-8 was to obtain irradiation performance data on monolithic fuel plates fabricated by friction bonding (FB) and isostatic hot pressing (HIP), as well as dispersion fuel plates that contain U-7Mo fuel particles alloyed with small amounts of Zr or Ti (see Fig.more » 1). The results of the monolithic plates destructively examined to date were presented at the 2007 RERTR meeting in Prague. This paper presents the first results on the dispersion plates with Ti and Zr additions to U-7Mo. The effect of Ti and Zr additions to U-7wt%Mo on the extent of fuel-aluminum interdiffusion, although measureable, is small in absolute terms because of the overwhelming effect of the 5% Si addition to the Al matrix. Ti additions to the U-7wt%Mo have no discernable effect on swelling behavior of the fuel. However, there are indications that the addition of Zr may have a destabilizing effect on fission gas behavior at high burnup.« less

[Nurturing fair play in competitive sports. Results from a study on competitively oriented youth soccer].

PubMed

Pilz, G A

2005-08-01

Apologists of sports praise them as an ideal way to prevent addiction and violence. Sports critics see it rather as a socialization authority on the morals of the fair foul. This contradiction was investigated based on an examination of fairness behaviour and fairness education in youth soccer as well as the question of the connection between sports and violence and the preventive possibilities of sports. Our results point to differences in understanding fairness according to age, sex and primarily performance/success orientation. Teenagers learn al ready at the latest in the C youth that it is important and right in the interest of success to break rules. Thus it applies that the more distinctive the success orientation, the more in formal and formal fair play degenerate into fictitious action morals of competitive sport and make way for morals of the "fair foul". The coaches play an important, even quite obviously the central role as socialization agents. In stead of learning fairness, the opposite is often conveyed to many young people in the organizations. However, our examinations also show that coach es can positively influence both fairness understanding and fairness behaviour of young footballers. Coach es are thus challenged as role models to exemplify fair play by their own actions.

Electrical latency predicts the optimal left ventricular endocardial pacing site: results from a multicentre international registry.

PubMed

Sieniewicz, Benjamin J; Behar, Jonathan M; Sohal, Manav; Gould, Justin; Claridge, Simon; Porter, Bradley; Niederer, Steve; Gamble, James H P; Betts, Tim R; Jais, Pierre; Derval, Nicolas; Spragg, David D; Steendijk, Paul; van Gelder, Berry M; Bracke, Frank A; Rinaldi, Christopher A

2018-04-23

The optimal site for biventricular endocardial (BIVENDO) pacing remains undefined. Acute haemodynamic response (AHR) is reproducible marker of left ventricular (LV) contractility, best expressed as the change in the maximum rate of LV pressure (LV-dp/dtmax), from a baseline state. We examined the relationship between factors known to impact LV contractility, whilst delivering BIVENDO pacing at a variety of LV endocardial (LVENDO) locations. We compiled a registry of acute LVENDO pacing studies from five international centres: Johns Hopkins-USA, Bordeaux-France, Eindhoven-The Netherlands, Oxford-United Kingdom, and Guys and St Thomas' NHS Foundation Trust, London-UK. In all, 104 patients incorporating 687 endocardial and 93 epicardial pacing locations were studied. Mean age was 66 ± 11 years, mean left ventricular ejection fraction 24.6 ± 7.7% and mean QRS duration of 163 ± 30 ms. In all, 50% were ischaemic [ischaemic cardiomyopathy (ICM)]. Scarred segments were associated with worse haemodynamics (dp/dtmax; 890 mmHg/s vs. 982 mmHg/s, P < 0.01). Delivering BiVENDO pacing in areas of electrical latency was associated with greater improvements in AHR (P < 0.01). Stimulating late activating tissue (LVLED >50%) achieved greater increases in AHR than non-late activating tissue (LVLED < 50%) (8.6 ± 9.6% vs. 16.1 ± 16.2%, P = 0.002). However, the LVENDO pacing location with the latest Q-LV, was associated with the optimal AHR in just 62% of cases. Identifying viable LVENDO tissue which displays late electrical activation is crucial to identifying the optimal BiVENDO pacing site. Stimulating late activating tissue (LVLED >50%) yields greater improvements in AHR however, the optimal location is frequently not the site of latest activation.

Latest developments for the IAGOS database: Interoperability and metadata

NASA Astrophysics Data System (ADS)

Boulanger, Damien; Gautron, Benoit; Thouret, Valérie; Schultz, Martin; van Velthoven, Peter; Broetz, Bjoern; Rauthe-Schöch, Armin; Brissebrat, Guillaume

2014-05-01

intercomparison. The optimal data transfer protocol is being investigated to insure the interoperability. To facilitate satellite and model validation, tools will be made available for co-location and comparison with IAGOS. We will enhance the JOIN application in order to properly display aircraft data as vertical profiles and along individual flight tracks and to allow for graphical comparison to model results that are accessible through interoperable web services, such as the daily products from the GMES/Copernicus atmospheric service.

Final STS-35 Columbia descent BET products and results for LaRC OEX investigations

NASA Technical Reports Server (NTRS)

Oakes, Kevin F.; Findlay, John T.; Jasinski, Rachel A.; Wood, James S.

1991-01-01

Final STS-35 'Columbia' descent Best Estimate Trajectory (BET) products have been developed for Langley Research Center (LaRC) Orbiter Experiments (OEX) investigations. Included are the reconstructed inertial trajectory profile; the Extended BET, which combines the inertial data and, in this instance, the National Weather Service atmospheric information obtained via Johnson Space Center; and the Aerodynamic BET. The inertial BET utilized Inertial Measurement Unit 1 (IMU1) dynamic measurements for deterministic propagation during the ENTREE estimation process. The final estimate was based on the considerable ground based C-band tracking coverage available as well as Tracking Data and Relay Satellite System (TDRSS) Doppler data, a unique use of the latter for endo-atmospheric flight determinations. The actual estimate required simultaneous solutions for the spacecraft position and velocity, spacecraft attitude, and six IMU parameters - three gyro biases and three accelerometer scale factor correction terms. The anchor epoch for this analysis was 19,200 Greenwich Mean Time (GMT) seconds which corresponds to an initial Shuttle altitude of approximately 513 kft. The atmospheric data incorporated were evaluated based on Shuttle derived considerations as well as comparisons with other models. The AEROBET was developed based on the Extended BET, the measured spacecraft configuration information, final mass properties, and the final Orbiter preoperation databook. The latter was updated based on aerodynamic consensus incrementals derived by the latest published FAD. The rectified predictions were compared versus the flight computed values and the resultant differences were correlated versus ensemble results for twenty-two previous STS entry flights.

INL Results for Phases I and III of the OECD/NEA MHTGR-350 Benchmark

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gerhard Strydom; Javier Ortensi; Sonat Sen

2013-09-01

The Idaho National Laboratory (INL) Very High Temperature Reactor (VHTR) Technology Development Office (TDO) Methods Core Simulation group led the construction of the Organization for Economic Cooperation and Development (OECD) Modular High Temperature Reactor (MHTGR) 350 MW benchmark for comparing and evaluating prismatic VHTR analysis codes. The benchmark is sponsored by the OECD's Nuclear Energy Agency (NEA), and the project will yield a set of reference steady-state, transient, and lattice depletion problems that can be used by the Department of Energy (DOE), the Nuclear Regulatory Commission (NRC), and vendors to assess their code suits. The Methods group is responsible formore » defining the benchmark specifications, leading the data collection and comparison activities, and chairing the annual technical workshops. This report summarizes the latest INL results for Phase I (steady state) and Phase III (lattice depletion) of the benchmark. The INSTANT, Pronghorn and RattleSnake codes were used for the standalone core neutronics modeling of Exercise 1, and the results obtained from these codes are compared in Section 4. Exercise 2 of Phase I requires the standalone steady-state thermal fluids modeling of the MHTGR-350 design, and the results for the systems code RELAP5-3D are discussed in Section 5. The coupled neutronics and thermal fluids steady-state solution for Exercise 3 are reported in Section 6, utilizing the newly developed Parallel and Highly Innovative Simulation for INL Code System (PHISICS)/RELAP5-3D code suit. Finally, the lattice depletion models and results obtained for Phase III are compared in Section 7. The MHTGR-350 benchmark proved to be a challenging simulation set of problems to model accurately, and even with the simplifications introduced in the benchmark specification this activity is an important step in the code-to-code verification of modern prismatic VHTR codes. A final OECD/NEA comparison report will compare the Phase I and III

The Latest Space-Borne Observations of TGFs from Fermi-GBM

NASA Technical Reports Server (NTRS)

Fishman, Gerald J.

2010-01-01

The Gamma-ray Burst Monitor (GBM) on the Fermi Gamma-ray Space Telescope Observatory (Fermi) is detecting about two TGFs per week. This rate has increased by a factor of approx.eight since launch when flight software was uploaded to the spacecraft in November 2009 in order to increase the sensitivity of GBM to TGFs. Weaker, un-triggered TGFs are now also being observed about once per day over selected low-latitude regions Americas. The high efficiency and time resolution (2 s) of GBM allows temporal features to be resolved so that some insight may be gained on the origin and transport of the gamma-ray photons through the atmosphere. TGFs are observed to be shorter than previously thought, with an average duration of approx.100 micro-s. The absolute times of TGFs are known to approx.10 micro-s, allowing accurate correlations of TGFs with lightning networks and other lightning-related phenomena. The events are observed in the thick bismuth germanate (BGO) scintillation detectors of GBM with photon energies above 40 MeV. Other new results on the temporal and spectral characteristics of TGFs will be presented, along with properties of several electron-positron TGF events that have been identified.

Ibrutinib in Waldenström macroglobulinemia: latest evidence and clinical experience

PubMed Central

Castillo, Jorge J.; Palomba, M. Lia; Advani, Ranjana; Treon, Steven P.

2016-01-01

Ibrutinib is an oral Bruton’s tyrosine kinase (BTK) inhibitor, which has recently gained approval by the United States (US) Food and Drug Administration (FDA) and the European Medicines Agency (EMA) for the treatment of patients with symptomatic Waldenström macroglobulinemia (WM). Herein, we review the role of BTK in the pathophysiology of WM, and present the results of the preclinical and clinical studies that led to the initial investigation and later approval of ibrutinib in WM. We also discuss aspects associated with ibrutinib therapy in WM patients, especially focusing on genomic profiling and the impact on response to ibrutinib, and the management of adverse events. PMID:27493708

Dark Matter Results from 54-Ton-Day Exposure of PandaX-II Experiment

NASA Astrophysics Data System (ADS)

Cui, Xiangyi; Abdukerim, Abdusalam; Chen, Wei; Chen, Xun; Chen, Yunhua; Dong, Binbin; Fang, Deqing; Fu, Changbo; Giboni, Karl; Giuliani, Franco; Gu, Linhui; Gu, Yikun; Guo, Xuyuan; Guo, Zhifan; Han, Ke; He, Changda; Huang, Di; He, Shengming; Huang, Xingtao; Huang, Zhou; Ji, Xiangdong; Ju, Yonglin; Li, Shaoli; Li, Yao; Lin, Heng; Liu, Huaxuan; Liu, Jianglai; Ma, Yugang; Mao, Yajun; Ni, Kaixiang; Ning, Jinhua; Ren, Xiangxiang; Shi, Fang; Tan, Andi; Wang, Cheng; Wang, Hongwei; Wang, Meng; Wang, Qiuhong; Wang, Siguang; Wang, Xiuli; Wang, Xuming; Wu, Qinyu; Wu, Shiyong; Xiao, Mengjiao; Xie, Pengwei; Yan, Binbin; Yang, Yong; Yue, Jianfeng; Zhang, Dan; Zhang, Hongguang; Zhang, Tao; Zhang, Tianqi; Zhao, Li; Zhou, Jifang; Zhou, Ning; Zhou, Xiaopeng; PandaX-II Collaboration

2017-11-01

We report a new search for weakly interacting massive particles (WIMPs) using the combined low background data sets acquired in 2016 and 2017 from the PandaX-II experiment in China. The latest data set contains a new exposure of 77.1 live days, with the background reduced to a level of 0.8 ×10-3 evt /kg /day , improved by a factor of 2.5 in comparison to the previous run in 2016. No excess events are found above the expected background. With a total exposure of 5.4 ×104 kg day , the most stringent upper limit on the spin-independent WIMP-nucleon cross section is set for a WIMP with mass larger than 100 GeV /c2 , with the lowest 90% C.L. exclusion at 8.6 ×10-47 cm2 at 40 GeV /c2 .

Progress with palbociclib in breast cancer: latest evidence and clinical considerations

PubMed Central

Rocca, Andrea; Schirone, Alessio; Maltoni, Roberta; Bravaccini, Sara; Cecconetto, Lorenzo; Farolfi, Alberto; Bronte, Giuseppe; Andreis, Daniele

2016-01-01

Deregulation of the cell cycle is a hallmark of cancer, and research on cell cycle control has allowed identification of potential targets for anticancer treatment. Palbociclib is a selective inhibitor of the cyclin-dependent kinases 4 and 6 (CDK4/6), which are involved, with their coregulatory partners cyclin D, in the G1-S transition. Inhibition of this step halts cell cycle progression in cells in which the involved pathway, including the retinoblastoma protein (Rb) and the E2F family of transcription factors, is functioning, although having been deregulated. Among breast cancers, those with functioning cyclin D-CDK4/6-Rb-E2F are mainly hormone-receptor (HR) positive, with some HER2-positive and rare triple-negative cases. Deregulation results from genetic or otherwise occurring hyperactivation of molecules subtending cell cycle progression, or inactivation of cell cycle inhibitors. Based on results of randomized clinical trials, palbociclib was granted accelerated approval by the US Food and Drug Administration (FDA) for use in combination with letrozole as initial endocrine-based therapy for metastatic disease in postmenopausal women with HR-positive, HER2-negative breast cancer, and was approved for use in combination with fulvestrant in women with HR-positive, HER2-negative advanced breast cancer with disease progression following endocrine therapy. This review provides an update of the available knowledge on the cell cycle and its regulation, on the alterations in cyclin D-CDK4/6-Rb-E2F axis in breast cancer and their roles in endocrine resistance, on the preclinical activity of CDK4/6 inhibitors in breast cancer, both as monotherapy and as partners of combinatorial synergic treatments, and on the clinical development of palbociclib in breast cancer. PMID:28203301

Latest Progress of Fault Detection and Localization in Complex Electrical Engineering

NASA Astrophysics Data System (ADS)

Zhao, Zheng; Wang, Can; Zhang, Yagang; Sun, Yi

2014-01-01

In the researches of complex electrical engineering, efficient fault detection and localization schemes are essential to quickly detect and locate faults so that appropriate and timely corrective mitigating and maintenance actions can be taken. In this paper, under the current measurement precision of PMU, we will put forward a new type of fault detection and localization technology based on fault factor feature extraction. Lots of simulating experiments indicate that, although there are disturbances of white Gaussian stochastic noise, based on fault factor feature extraction principal, the fault detection and localization results are still accurate and reliable, which also identifies that the fault detection and localization technology has strong anti-interference ability and great redundancy.

CrIS/ATMS Retrievals Using the Latest AIRS/AMSU Retrieval Methodology

NASA Technical Reports Server (NTRS)

Susskind, Joel; Kouvaris, Louis C.; Blaisdell, John; Iredell, Lena

2015-01-01

This research is being done under the NPP Science Team Proposal: Analysis of CrISATMS Using an AIRS Version 6-like Retrieval Algorithm Objective: Generate a long term CrISATMS level-3 data set that is consistent with that of AIRSAMSU Approach: Adapt the currently operational AIRS Science Team Version-6 Retrieval Algorithm, or an improved version of it, for use with CrISATMS data. Metric: Generate monthly mean level-3 CrISATMS climate data sets and evaluate the results by comparison of monthly mean AIRSAMSU and CrISATMS products, and more significantly, their inter-annual differences and, eventually, anomaly time series. The goal is consistency between the AIRSAMSU and CrISATMS climate data sets.

The Feasibility of Avoiding Future Climate Impacts: Results from the AVOID Programmes

NASA Astrophysics Data System (ADS)

Lowe, J. A.; Warren, R.; Arnell, N.; Buckle, S.

2014-12-01

The AVOID programme and its successor, AVOID2, have focused on answering three core questions: how do we characterise potentially dangerous climate change and impacts, which emissions pathways can avoid at least some of these impacts, and how feasible are the future reductions needed to significantly deviate from a business-as-usual future emissions pathway. The first AVOID project succeeded in providing the UK Government with evidence to inform its position on climate change. A key part of the work involved developing a range of global emissions pathways and estimating and understanding the corresponding global impacts. This made use of a combination of complex general circulation models, simple climate models, pattern-scaling and state-of-the art impacts models. The results characterise the range of avoidable impacts across the globe in several key sectors including river and coastal flooding, cooling and heating energy demand, crop productivity and aspects of biodiversity. The avoided impacts between a scenario compatible with a 4ºC global warming and one with a 2ºC global warming were found to be highly sector dependent and avoided fractions typically ranged between 20% and 70%. A further key aspect was characterising the magnitude of the uncertainty involved, which is found to be very large in some impact sectors although the avoided fraction appears a more robust metric. The AVOID2 programme began in 2014 and will provide results in the run up to the Paris CoP in 2015. This includes new post-IPCC 5th assessment evidence to inform the long-term climate goal, a more comprehensive assessment of the uncertainty ranges of feasible emission pathways compatible with the long-term goal and enhanced estimates of global impacts using the latest generation of impact models and scenarios.

Dinosaurs on the North Slope, Alaska: High latitude, latest cretaceous environments

USGS Publications Warehouse

Brouwers, E.M.; Clemens, W.A.; Spicer, R.A.; Ager, T.A.; Carter, L.D.; Sliter, W.V.

1987-01-01

Abundant skeletal remains demonstrate that lambeosaurine hadrosaurid, tyrannosaurid, and troodontid dinosaurs lived on the Alaskan North Slope during late Campanian-early Maestrichtian time (about 66 to 76 million years ago) in a deltaic environment dominated by herbaceous vegetation. The high ground terrestrial plant community was a mild- to cold-temperate forest composed of coniferous and broad leaf trees. The high paleolatitude (about 70?? to 85?? North) implies extreme seasonal variation in solar insolation, temperature, and herbivore food supply. Great distances of migration to contemporaneous evergreen floras and the presence of both juvenile and adult hadrosaurs suggest that they remained at high latitudes year-round. This challenges the hypothesis that short-term periods of darkness and temperature decrease resulting from a bolide impact caused dinosaurian extinction.

[Psychopathy in children and teenagers: models, theories and the latest research].

PubMed

Halty, Lucía; Martínez, Ana; Requena, Carmen; Santos, Juan M; Ortiz, Tomás

2011-03-01

Most research about psychopathy have been conducted on adults. It is important to focus on the study of psychopathy in children to better understand the evolution of this disorder. This article focuses on a brief review of the contributions from psychology, where trait callous unemotional is closely related to the presence of antisocial behavior and conduct disorders, therefore, is an important factor in development of psychopathy. Also, we reviewed from the perspective of neuroscience where we found a reduced response of the amygdala in young people with presence of characteristic high scores on callous unemotional and psychopathy. We have also found an abnormal response in the ventromedial prefrontal cortex. It is important to note these results because children with these characteristics are very difficult to socialize.

Statistics in Schools

Science.gov Websites

Overview Math History Geography Sociology English About Latest Information SIS in the News Census 101 for , Other About Contact Information Search Math History/Social Studies Geography Sociology Latest Information Latest Information Latest Information Latest Information English Grades K - 2 Grades 3 - 5 Grades

Foundations and latest advances in replica exchange transition interface sampling.

PubMed

Cabriolu, Raffaela; Skjelbred Refsnes, Kristin M; Bolhuis, Peter G; van Erp, Titus S

2017-10-21

Nearly 20 years ago, transition path sampling (TPS) emerged as an alternative method to free energy based approaches for the study of rare events such as nucleation, protein folding, chemical reactions, and phase transitions. TPS effectively performs Monte Carlo simulations with relatively short molecular dynamics trajectories, with the advantage of not having to alter the actual potential energy surface nor the underlying physical dynamics. Although the TPS approach also introduced a methodology to compute reaction rates, this approach was for a long time considered theoretically attractive, providing the exact same results as extensively long molecular dynamics simulations, but still expensive for most relevant applications. With the increase of computer power and improvements in the algorithmic methodology, quantitative path sampling is finding applications in more and more areas of research. In particular, the transition interface sampling (TIS) and the replica exchange TIS (RETIS) algorithms have, in turn, improved the efficiency of quantitative path sampling significantly, while maintaining the exact nature of the approach. Also, open-source software packages are making these methods, for which implementation is not straightforward, now available for a wider group of users. In addition, a blooming development takes place regarding both applications and algorithmic refinements. Therefore, it is timely to explore the wide panorama of the new developments in this field. This is the aim of this article, which focuses on the most efficient exact path sampling approach, RETIS, as well as its recent applications, extensions, and variations.

Foundations and latest advances in replica exchange transition interface sampling

NASA Astrophysics Data System (ADS)

Cabriolu, Raffaela; Skjelbred Refsnes, Kristin M.; Bolhuis, Peter G.; van Erp, Titus S.

2017-10-01

Nearly 20 years ago, transition path sampling (TPS) emerged as an alternative method to free energy based approaches for the study of rare events such as nucleation, protein folding, chemical reactions, and phase transitions. TPS effectively performs Monte Carlo simulations with relatively short molecular dynamics trajectories, with the advantage of not having to alter the actual potential energy surface nor the underlying physical dynamics. Although the TPS approach also introduced a methodology to compute reaction rates, this approach was for a long time considered theoretically attractive, providing the exact same results as extensively long molecular dynamics simulations, but still expensive for most relevant applications. With the increase of computer power and improvements in the algorithmic methodology, quantitative path sampling is finding applications in more and more areas of research. In particular, the transition interface sampling (TIS) and the replica exchange TIS (RETIS) algorithms have, in turn, improved the efficiency of quantitative path sampling significantly, while maintaining the exact nature of the approach. Also, open-source software packages are making these methods, for which implementation is not straightforward, now available for a wider group of users. In addition, a blooming development takes place regarding both applications and algorithmic refinements. Therefore, it is timely to explore the wide panorama of the new developments in this field. This is the aim of this article, which focuses on the most efficient exact path sampling approach, RETIS, as well as its recent applications, extensions, and variations.

AEOLUS mission: the latest preparations before launch

NASA Astrophysics Data System (ADS)

Culoma, A.; Elfving, A.; Meynart, R.; Straume, A.; Wernham, D.

2017-09-01

The European Space Agency is developing a direct detection Doppler Wind Lidar for measuring wind profiles from space. The main objective of Aeolus is to provide tropospheric and lower stratospheric wind profiles globally for the improvement of weather forecast on short and medium term. Aeolus data are expected to greatly contribute to weather and air quality monitoring and to scientific advances in atmospheric dynamics. The UV Lidar instrument, ALADIN, will deliver horizontally-projected single line-of-sight wind profiles from the Doppler shift of molecular and particle backscatter. The development of the AEOLUS mission passed a major milestone with the integration of the full instrument and its functional and performance tests in 2016 and a 6-month life test of the spare UV laser transmitter. The satellite has been assembled and has successfully been subjected to a programme of functional and environmental (vibration, acoustic, shock, EMC) tests. The preparation of thermal vacuum testing, including instrument performance in vacuum, is close to completion.

Latest Trends in German Political Socialisation Research.

ERIC Educational Resources Information Center

Claussen, Bernhard

1979-01-01

Presents an overview of the most notable among recent books on political socialization in West Germany and indicates trends among these publications in areas of research methodology, objectives, stress on empirical studies, and theoretical models. (Author/DB)

NASA's MISR Spots Alaskan Volcano's Latest Eruption

NASA Image and Video Library

2017-06-02

The tiny Aleutian island of Bogoslof in Alaska, erupting regularly since December 2016, produced fresh activity on Sunday, May 28, 2017. Bogoslof is a stratovolcano fueled by the subduction of the Pacific Plate under the North American Plate and forms part of the larger Aleutian Arc, which includes more than 60 volcanoes on the Aleutian Islands and the Aleutian Range on the Alaska mainland. Previous to its recent period of activity, Bogoslof had last erupted in 1992, and its above-water surface area was a mere 0.11 square miles (0.29 square kilometers). As of March 11, the most recent data available, the area of the island had tripled to 0.38 square miles (0.98 square kilometers). The event on May 28 produced an ash cloud that reached 40,000 feet (12 km) in altitude, causing the Alaskan Volcano Observatory to issue a red alert for air travel in the area. Volcanic ash can cause major damage to aircraft engines, and the region is close to several major air routes between North America and Asia. On May 28, 2017, at approximately 2:23 p.m. local time, NASA's Terra satellite passed over Bogoslof, less than 10 minutes after the eruption began. MISR has nine cameras that view Earth at different angles. It takes slightly less than seven minutes for all nine cameras to view the same location on Earth. An animation made from the images from the nine MISR cameras, captured between 2:19 and 2:26 p.m., demonstrates how the angled views give a glimpse of the underside of the growing plume of volcanic ash, showing the eruption column widening into the cloud at the top. The animation is available at https://photojournal.jpl.nasa.gov/catalog/PIA21655