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Sample records for gardenia jasminoides ellis

  1. In vitro antioxidant activity of polysaccharide from Gardenia jasminoides ellis

    USGS Publications Warehouse

    Fan, Y.; Ge, Z.; Luo, A.

    2011-01-01

    A water-soluble polysaccharide, GP, was isolated from Gardenia jasminoides Ellis through hot water extraction followed by ethanol precipitation. The in vitro free radicals scavenging tests exhibited that GP has significant scavenging abilities especially for ABTS, DPPH, and hydroxyl radicals, which suggests that the polysaccharide GP is a novel antioxidant. ?? 2011 Academic Journals.

  2. Chemical constituents from the fruits of Gardenia jasminoides Ellis.

    PubMed

    Yu, Yang; Feng, Xiao-Lin; Gao, Hao; Xie, Zuo-Lei; Dai, Yi; Huang, Xiao-Jun; Kurihara, Hiroshi; Ye, Wen-Cai; Zhong, Yi; Yao, Xin-Sheng

    2012-04-01

    A new lignan glucoside, (+)-(7S,8R,8'R)-lyoniresinol 9-O-β-D-(6″-O-trans-sinapoyl)glucopyranoside (1), and a new iridoid glucoside, 10-O-trans-sinapoylgeniposide (2), together with eight known compounds, were isolated from the fruits of Gardenia jasminoides Ellis. The structures of the isolates were elucidated by extensive spectroscopic studies, including UV, IR, 1D and 2D NMR, ESI-MS, HR-ESI-MS, and CD experiments. The short-term-memory-enhancement activities of some compounds were evaluated on an Aβ transgenic drosophila model.

  3. The Effect of Various Media and Hormones via Suspension Culture on Secondary Metabolic Activities of (Cape Jasmine) Gardenia jasminoides Ellis

    PubMed Central

    Mat Taha, Rosna; Rashid, Kamaludin; Syafawati Yaacob, Jamilah

    2014-01-01

    The leaf of Gardenia jasminoides Ellis was used as explants and was cultured on MS and WPM media supplemented with various concentrations of NAA, IAA, 2,4-D, IBA, TDZ, and Kn (0 to 5 mg L−1 with 0.5 increment). After six months, the higher percentage of callus (100%) and the best dry and fresh weight of callus were formed on WPM medium supplemented with 2,4-D and NAA (2.0-3.0 mg L−1) and this amount was decreased from (84%) to (69%) when this media supplemented with Kinetin and TDZ (1 mg L−1) respectively were used. Leaf segments cultured on WPM media added with Kn (1 mg L−1) and TDZ (2 mg L−1) yielded the least amount of callus. It was found that WPM media added with IAA (4.5–5.0 mg L−1) were optimum for root induction from G. jasminoides plantlets. Antibacterial screening of leaf extracts (in vivo) showed no inhibitory effect against E. coli, P. aeruginosa, S. aureus, and B. cereus, in contrast to callus extracts from leaf cultures supplemented with NAA, which showed inhibition activity against E. coli and B. cereus. The callus extracts from leaf cultures grown on both MS and WPM media showed higher antioxidant and superoxide dismutase activities than leaf extracts. PMID:24967432

  4. The effect of various media and hormones via suspension culture on secondary metabolic activities of (Cape Jasmine) Gardenia jasminoides Ellis.

    PubMed

    Farzinebrahimi, Reza; Mat Taha, Rosna; Rashid, Kamaludin; Syafawati Yaacob, Jamilah

    2014-01-01

    The leaf of Gardenia jasminoides Ellis was used as explants and was cultured on MS and WPM media supplemented with various concentrations of NAA, IAA, 2,4-D, IBA, TDZ, and Kn (0 to 5 mg L(-1) with 0.5 increment). After six months, the higher percentage of callus (100%) and the best dry and fresh weight of callus were formed on WPM medium supplemented with 2,4-D and NAA (2.0-3.0 mg L(-1)) and this amount was decreased from (84%) to (69%) when this media supplemented with Kinetin and TDZ (1 mg L(-1)) respectively were used. Leaf segments cultured on WPM media added with Kn (1 mg L(-1)) and TDZ (2 mg L(-1)) yielded the least amount of callus. It was found that WPM media added with IAA (4.5-5.0 mg L(-1)) were optimum for root induction from G. jasminoides plantlets. Antibacterial screening of leaf extracts (in vivo) showed no inhibitory effect against E. coli, P. aeruginosa, S. aureus, and B. cereus, in contrast to callus extracts from leaf cultures supplemented with NAA, which showed inhibition activity against E. coli and B. cereus. The callus extracts from leaf cultures grown on both MS and WPM media showed higher antioxidant and superoxide dismutase activities than leaf extracts.

  5. Crocetin, a carotenoid from Gardenia jasminoides Ellis, protects against hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats.

    PubMed

    Higashino, Saori; Sasaki, Yasuto; Giddings, John C; Hyodo, Kanae; Sakata, Shigeko Fujimoto; Matsuda, Koichi; Horikawa, Yoko; Yamamoto, Junichiro

    2014-09-01

    Crocetin is a natural carotenoid dicarboxylic acid that is found in the fruit of Gardenia jasminoides Ellis (Cape Jasmine) and in the stamen and pistil of Crocus sativus L. (saffron). It is used worldwide as an important spice, food colorant, and herbal medicine. In the current investigation, we have examined the cardiovascular effects of crocetin using stroke-prone spontaneously hypertensive rats (SHRSPs). Male SHRSPs (6 weeks old) were classified into three groups: a control group and two crocetin groups (25 and 50 mg/kg/day). The animals were given crocetin for 3 weeks. Body weights in each group were not significantly different during the treatment period, but the increase in systolic blood pressures observed with age was significantly moderated by crocetin. Thrombogenesis, assessed using a He-Ne laser technique in pial vessels, was significantly decreased. Antioxidant activity, assessed by measuring urinary 8-hydroxy-2'-deoxyguanosine levels, together with urinary nitric oxide (NO) metabolite levels, was increased significantly after treatment. Acetylcholine-induced vasodilation was measured using the aorta and indicated that endothelial function was significantly improved by crocetin. These results strongly suggest that the antihypertensive and antithrombotic effects of crocetin were related to an increase in bioavailable NO, possibly mediated by decreased inactivation of NO by reactive oxygen species.

  6. The biosynthesis of palladium nanoparticles by antioxidants in Gardenia jasminoides Ellis: long lifetime nanocatalysts for p-nitrotoluene hydrogenation

    NASA Astrophysics Data System (ADS)

    Jia, Lishan; Zhang, Qian; Li, Qingbiao; Song, Hao

    2009-09-01

    Gardenia jasminoides Ellis' water crude extract was used for the bioreduction of palladium chloride in this paper. The UV-vis spectrum, x-ray diffraction spectrum measurement, the Fourier transform infrared spectroscopy and TEM technique confirmed the formation of palladium nanoparticles and identified antioxidants including geniposide, chlorogenic acid, crocins and crocetin were reducing and stabilizing agents for synthesizing palladium nanoparticles in water crude extract. The particle size and dispersity were temperature-dependent. The particle sizes ranged from 3 to 5 nm and revealed the best dispersity at 70 °C. Catalytic performance of the biosynthetic Pd nanoparticles with good dispersity was investigated by hydrogenation of p-nitrotoluene. The catalysts showed a conversion of 100% under conditions of 5 MPa, 150 °C for 2 h. The selectivity of p-methyl-cyclohexylamine achieved 26.3%. The catalyst was recycled five times with no agglomeration and maintained activity, which was attributed to the appropriate protection of the antioxidants. On the basis of the study, it appears to be a new promising biosynthetic nanocatalyst for the development of an industrial process.

  7. 2-methyl-L-erythritol glycosides from Gardenia jasminoides.

    PubMed

    Yang, Liguo; Peng, Kaifeng; Zhao, Shizhe; Zhao, Feng; Chen, Lixia; Qiu, Feng

    2013-09-01

    Two new glycosides, 2-methyl-L-erythritol-4-O-(6-O-trans-sinapoyl)-β-D-glucopyranoside (1) and 2-methyl-L-erythritol-1-O-(6-O-trans-sinapoyl)-β-D-glucopyranoside (2), along with two known triterpenoids (3-4), four quinic acid derivatives (5-8) and one flavonoid (9) were isolated from the fruit of Gardenia jasminoides. Their structures were elucidated through MS and 2D NMR experiments (HMQC and HMBC). Inhibitory effects of the isolated compounds on nitric oxide production in lipopolysaccharide-activated macrophages were evaluated. Though 2-methyl-D-erythritol and its glycosides have been reported in a few references, this is the first report about 2-methyl-L-erythritol glycosides. Based on this finding, we propose that 2-methyl-L-erythritol might be a new intermediate in the non-mevalonate biosynthesis of terpenoids.

  8. Gardenia jasminoides attenuates hepatocellular injury and fibrosis in bile duct-ligated rats and human hepatic stellate cells

    PubMed Central

    Chen, Ying-Hua; Lan, Tian; Li, Jing; Qiu, Chun-Hui; Wu, Teng; Gou, Hong-Ju; Lu, Min-Qiang

    2012-01-01

    AIM: To investigate the anti-hepatofibrotic effects of Gardenia jasminoides in liver fibrosis. METHODS: Male Sprague-Dawley rats underwent common bile duct ligation (BDL) for 14 d and were treated with Gardenia jasminoides by gavage. The effects of Gardenia jasminoides on liver fibrosis and the detailed molecular mechanisms were also assessed in human hepatic stellate cells (LX-2) in vitro. RESULTS: Treatment with Gardenia jasminoides decreased serum alanine aminotransferase (BDL vs BDL + 100 mg/kg Gardenia jasminoides, 146.6 ± 15 U/L vs 77 ± 6.5 U/L, P = 0.0007) and aspartate aminotransferase (BDL vs BDL + 100 mg/kg Gardenia jasminoides, 188 ± 35.2 U/L vs 128 ± 19 U/L, P = 0.005) as well as hydroxyproline (BDL vs BDL + 100 mg/kg Gardenia jasminoides, 438 ± 40.2 μg/g vs 228 ± 10.3 μg/g liver tissue, P = 0.004) after BDL. Furthermore, Gardenia jasminoides significantly reduced liver mRNA and/or protein expression of transforming growth factor β1 (TGF-β1), collagen type I (Col I) and α-smooth muscle actin (α-SMA). Gardenia jasminoides significantly suppressed the upregulation of TGF-β1, Col I and α-SMA in LX-2 exposed to recombinant TGF-β1. Moreover, Gardenia jasminoides inhibited TGF-β1-induced Smad2 phosphorylation in LX-2 cells. CONCLUSION: Gardenia jasminoides exerts antifibrotic effects in the liver fibrosis and may represent a novel antifibrotic agent. PMID:23326120

  9. Gardenia jasminoides protects against cerulein-induced acute pancreatitis

    PubMed Central

    Jung, Won-Seok; Chae, Young-Seok; Kim, Do-Yun; Seo, Sang-Wan; Park, Hee-Je; Bae, Gi-Sang; Kim, Tae-Hyeon; Oh, Hyo-Jeong; Yun, Ki-Jung; Park, Rae-Kil; Kim, Jong-Suk; Kim, Eun-Cheol; Hwang, Sung-Yeon; Park, Sung-Joo; Song, Ho-Joon

    2008-01-01

    AIM: To investigate the effect of Gardenia jasminoides (GJ) on cerulein-induced acute pancreatitis (AP) in mice. METHODS: C57BL/6 mice weighing 18-20 g were divided into three groups. (1) Normal saline-treated group, (2) treatment with GJ at a dose of 0.1 g/kg, (3) treatment with GJ at a dose of 1 g/kg. GJ was administered orally (n = 6 per group) for 1 wk. Three hours later, the mice were given an intraperitoneal injection of cerulein (50 μg/kg), a stable cholecystokinin (CCK) analogue, every hour for a total of 6 h as described previously. The mice were sacrificed at 6 h after completion of cerulein injections. Blood samples were obtained to determine serum amylase, lipase and cytokine levels. The pancreas was rapidly removed for morphologic examination and scoring. A portion of pancreas was stored at -70°C and prepared for the measurement of tissue myeloperoxidase (MPO) activity, an indicator of neutrophil sequestration, and for reverse-transcriptase PCR (RT-PCR) and real-time PCR measurements. RESULTS: Treatment with GJ decreased significantly the severity of pancreatitis and pancreatitis-associated lung injury. Treatment with GJ attenuated the severity of AP compared with saline-treated mice, as shown by reduction in pancreatic edema, neutrophil infiltration, serum amylase and lipase levels, serum cytokine levels, and mRNA expression of multiple inflammatory mediators. CONCLUSION: These results suggest that GJ attenuated the severity of AP as well as pancreatitis-associated lung injury. PMID:18985809

  10. Gardenia jasminoides extract-capped gold nanoparticles reverse hydrogen peroxide-induced premature senescence.

    PubMed

    Chae, Seon Yeong; Park, Sun Young; Park, Jin Oh; Lee, Kyu Jin; Park, Geuntae

    2016-11-01

    This study reports a green approach for synthesis of gold nanoparticles using Gardenia jasminoides extract, and specifically, can potentially enhance anti senescence activity. Biological synthesis of gold nanoparticles is ecofriendly and effective for the development of environmentally sustainable nanoparticles compared with existing methods. Here, we developed a simple, fast, efficient, and ecofriendly approach to the synthesis of gold nanoparticles by means of a Gardenia jasminoides extract. These G. jasminoides extract-capped gold nanoparticles (GJ-GNPs) were characterized by UV-vis, high resolution transmission electron microscopy (HR-TEM), X-ray diffraction (XRD), and Furrier transform infrared spectroscopy (FT-IR). The synthesized GJ-GNPs turned red and showed maximal absorbance at 540nm. Thus, GJ-GNPs were synthesized successfully. We hypothesized that GJ-GNPs would protect ARPE19 cells from hydrogen peroxide-induced premature senescence. SA-β-gal activity was elevated in hydrogen peroxide-treated cells, however, this effect was attenuated by GJ-GNP treatment. Moreover, compared with the normal control, hydrogen peroxide treatment significantly increased lysosome content of the cells and production of reactive oxygen species (ROS). GJ-GNPs effectively attenuated the increase in lysosome content and ROS production in these senescent cells. According to cell cycle analysis, G2/M arrest was promoted by hydrogen peroxide treatment in ARPE19 cells, however, this change was reversed by GJ-GNPs. Western blot analysis showed that treatment with GJ-GNPs increased the expression of p53, p21, SIRT3, HO-1, and NQO1 in senescent cells. Our findings should advance the understanding of premature senescence and may lead to therapeutic use of GJ-GNPs in retina-related regenerative medicine.

  11. HPLC-Analysis of Polyphenolic Compounds in Gardenia jasminoides and Determination of Antioxidant Activity by Using Free Radical Scavenging Assays

    PubMed Central

    Uddin, Riaz; Saha, Moni Rani; Subhan, Nusrat; Hossain, Hemayet; Jahan, Ismet Ara; Akter, Raushanara; Alam, Ashraful

    2014-01-01

    Purpose: Gardenia jasminoides is a traditional medicinal plant rich in anti-inflammatory flavonoids and phenolic compounds and used for the treatment of inflammatory diseases and pain. In this present study, antioxidant potential of Gardenia jasminoides leaves extract was evaluated by using various antioxidant assays. Methods: Various antioxidant assays such as 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay, reducing power and total antioxidant capacity expressed as equivalent to ascorbic acid were employed. Moreover, phenolic compounds were detected by high-performance liquid chromatography (HPLC) coupled with diode-array detection. Results: The methanol extract showed significant free radical scavenging activities in DPPH radical scavenging antioxidant assays compared to the reference antioxidant ascorbic acid. Total antioxidant activity was increased in a dose dependent manner. The extract also showed strong reducing power. The total phenolic content was determined as 190.97 mg/g of gallic acid equivalent. HPLC coupled with diode-array detection was used to identify and quantify the phenolic compounds in the extracts. Gallic acid, (+)-catechin, rutin hydrate and quercetin have been identified in the plant extracts. Among the phenolic compounds, catechin and rutin hydrate are present predominantly in the extract. The accuracy and precision of the presented method were corroborated by low intra- and inter-day variations in quantitative results in leaves extract. Conclusion: These results suggest that phenolic compounds and flavonoids might contribute to high antioxidant activities of Gardenia jasminoides leaves. PMID:24754012

  12. Monoamine Oxidase and Dopamine β-Hydroxylase Inhibitors from the Fruits of Gardenia jasminoides

    PubMed Central

    Kim, Ji Ho; Kim, Gun Hee; Hwang, Keum Hee

    2012-01-01

    This research was designed to determine what components of Gardenia jasminoides play a major role in inhibiting the enzymes related antidepressant activity of this plant. In our previous research, the ethyl acetate fraction of G. jasminosides fruits inhibited the activities of both monoamine oxidase-A (MAO-A) and monoamine oxidase-B (MAO-B), and oral administration of the ethanolic extract slightly increased serotonin concentrations in the brain tissues of rats and decreased MAO-B activity. In addition, we found through in vitro screening test that the ethyl acetate fraction showed modest inhibitory activity on dopamine-β hydroxylase (DBH). The bioassay-guided fractionation led to the isolation of five bio-active compounds, protocatechuic acid (1), geniposide (2), 6'-O-trans-p-coumaroylgeniposide (3), 3,5-d-ihydroxy-1,7-bis (4-hydroxyphenyl) heptanes (4), and ursolic acid (5), from the ethyl acetate fraction of G. jasminoides fruits. The isolated compounds showed different inhibitory potentials against MAO-A, -B, and DBH. Protocatechuic acid showed potent inhibition against MAO-B (IC50 300 μmol/L) and DBH (334 μmol/L), exhibiting weak MAO-A inhibition (2.41 mmol/L). Two iridoid glycosides, geniposide (223 μmol/L) and 6'-O-trans-p-coumaroylgeniposide (127μmol/L), were selective MAO-B inhibitor. Especially, 6'-O-trans-p-coumaroylgeniposide exhibited more selective MAO-B inhibition than deprenyl, well-known MAO-B inhibitor for the treatment of early-stage Parkinson’s disease. The inhibitory activity of 3,5-di-hydroxy-1,7-bis (4-hydroxyphenyl) heptane was strong for MAO-B (196 μmol/L), modest for MAO-A (400 μmol/L), and weak for DBH (941 μmol/L). Ursolic acid exhibited significant inhibition of DBH (214 μmol/L), weak inhibition of MAO-B (780 μmol/L), and no inhibition against MAO-A. Consequently, G. jasminoides fruits are considerable for development of biofunctional food materials for the combination treatment of depression and neurodegenerative disorders

  13. Isolation and characterization of water-soluble intermediates of blue pigments transformed from geniposide of Gardenia jasminoides.

    PubMed

    Park, Jee-Eun; Lee, Jae-Youn; Kim, Hong-Gyu; Hahn, Tae-Ryong; Paik, Young-Sook

    2002-10-23

    Gardenia blue dye was obtained through the reaction of methylamine with genipin, the aglycone of geniposide isolated from the fruits of Gardenia jasminoides. The resulting blue pigments were passed through Bio-Gel P-2 resin yielding five fractions, GM1-GM5. Four fractions (GM1-GM4) were all blue pigments, and the first eluted higher molecular weight fraction GM1 had a higher tinctorial strength than the later eluted lower molecular weight fractions, GM2-GM4. The last eluted GM5 fraction with lambda(max) of 292 nm was colorless and was confirmed as the true intermediate of the blue pigments on the basis of UV-vis spectrophotometric evidence. The GM5 fraction was composed of two epimeric isomers, and their structures were characterized by (1)H NMR, (1)H-(1)H COSY, (13)C NMR, and HMQC and HMBC spectral measurements.

  14. A strategy for identification and structural characterization of compounds from Gardenia jasminoides by integrating macroporous resin column chromatography and liquid chromatography-tandem mass spectrometry combined with ion-mobility spectrometry.

    PubMed

    Wang, Lu; Liu, Shu; Zhang, Xueju; Xing, Junpeng; Liu, Zhiqiang; Song, Fengrui

    2016-06-24

    In this paper, an analysis strategy integrating macroporous resin (AB-8) column chromatography and high performance liquid chromatography-electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS/MS) combined with ion mobility spectrometry (IMS) was proposed and applied for identification and structural characterization of compounds from the fruits of Gardenia jasminoides. The extracts of G. jasminoides were separated by AB-8 resin column chromatography combined with reversed phase liquid chromatography (C18 column) and detected by electrospray ionization tandem mass spectrometry. Additionally, ion mobility spectrometry (IMS) was employed as a supplementary separation technique to discover previously undetected isomers from the fruits of G. jasminoides. A total of 71 compounds, including iridoids, flavonoids, triterpenes, monoterpenoids, carotenoids and phenolic acids were identified by the characteristic high resolution mass spectrometry and the ESI-MS/MS fragmentations. In conclusion, the IMS-MS technique achieved the separation of isomers in crocin-3 and crocin-4 according to their acquired mobility drift times differing from classical analysis by mass spectrometry. The proposed strategy can be used as a highly sensitive and efficient procedure for identification and separation isomeric components in extracts of herbal medicines.

  15. Isolation and purification of six iridoid glycosides from gardenia jasminoides fruit by medium-pressure liquid chromatography combined with macroporous resin chromatography.

    PubMed

    Wang, Yun; Liu, Hui; Shen, Lifeng; Yao, Lan; Ma, Yinlian; Yu, Dingrong; Chen, Jianhong; Li, Puling; Chen, Ying; Zhang, Cun

    2015-12-01

    Gardeniae fructus is one of the most frequently used herbs in traditional Chinese medicine. In the present study, a process for the enrichment of six iridoid glycosides from Gardeniae fructus was developed using medium-pressure liquid chromatography combined with macroporous resin and reversed-phase chromatography. The purities of different fractions from Gardeniae fructus were assessed using quantitative high-performance liquid chromatography. After fractionation using HPD-100 column chromatography, a 30% ethanol fraction was selected based on high-performance liquid chromatography and liquid chromatography with mass spectrometry qualitative analysis to separate and purify. Based on the orientation analysis results, six compounds-deacetyl asperulosidic acid methyl ester, gardenoside, ixoroside, scandoside methyl ester, genipin-1-O-β-d-gentiobioside, and geniposide-were successfully isolated and purified in three to four combined steps from Gardeniae fructus. The purities of these compounds were found by high-performance liquid chromatography analysis to be 97.9, 98.1, 95.5, 96.3, 97.1, and 98.7%, respectively. Moreover, their structures were elucidated by NMR spectroscopy and liquid chromatography with tandem mass spectrometry. The separation process was highly efficient, rapid, and accurate, making it a potential approach for the large-scale production of iridoids in the laboratory and providing several marker compounds for quality control. This procedure may be meaningful for the purification of other natural products used in traditional Chinese medicine.

  16. Havelock Ellis, eugenicist.

    PubMed

    Crozier, Ivan

    2008-06-01

    This article examines the contributions made towards eugenic thought in the late nineteenth and early twentieth centuries by Havelock Ellis (1859-1939). Ellis was a significant social reformer who worked on the problems of sexuality from a scientific-naturalist secular perspective. In the later phases of his work, after he had completed much of his writing on sexuality, Ellis concentrated on issues of feminism and eugenics--problems he thought were interlinked. In this paper, I integrate his ideas about these subjects, and consider the ways in which Ellis and other liberal social reformers created a 'eugenic subject' in order to frame their arguments about social problems.

  17. [Research and development of Fructus Gardeniae].

    PubMed

    Ni, Hui-Yan; Zhang, Zhao-Hui; Fu, Hai-Zhen

    2006-04-01

    Survey on research and development of Fructus Gardeniae in the recent 10 years. Gardenia yellow has been used for food colorent, medicine, feedingstuff and cosmetic. Garnedia blue has been used for developing another pigment with red and yellow. Fructus Gardeniae has been used in digestive system for cholecyst constracting and gall-stone eliminating, for declining peroxide on SAP mouse and increasing immune ability, for protecting liver against cancel, anti-acetylcholinic restraining on stomach enginery, in cardiovascular system it has been used for centrally anti-hypertension, preventing atheroma and thrombus, also Fructus Gardeniae has been used for anti-inflammation, treating parenchyma injure etc. Geniposide used for increasing production in agriculture has wider perspect.

  18. Early Treatment in Shock. Addendum

    DTIC Science & Technology

    2012-08-01

    from gardenia root (Gardenia jasminoides Ellis). It is com- monly sold in the United States as an herbal supplement . In terms of crocetin’s fundamental...but results of 14 the available literature collectively allow the conclusion that L-arginine supplementation 15 can be beneficial in ameliorating the...were designed to test two 19 hypotheses. First, L-arginine supplementation during resuscitation will improve survival 20 from lethal hemorrhagic

  19. [Analysis on formula raw materials application of health food containing Gardeniae fructus].

    PubMed

    Zhang, Yi-guang; Tang, Shi-huan; Jia, Qiang; Meng, Fan-yun

    2014-11-01

    In this article we built formula database of health food containing Gardeniae Fructus with Traditional Chinese Medicine Inheritance Support System (V2.0). And on this basis, use data mining method such as association rules of the software, to analyze commonly used formula raw materials or materials combination of formula containing Gardeniae Fructus and raw material application having assisted function formula to protect chemical liver injury. The result shows that of the 71 health food formulas containing Gardeniae Fructus, most used materials are Gardeniae Fructus, Lycii Fructus, Angelica Sinensis Radix, Poria and so on. Commonly used materials combination mostly are Gardeniae Fructus and Lycii Fructus, Gardeniae Fructus and Angelica Sinensis Radix, Gardeniae Fructus and Poria, Gardeniae Fructus and Paeonia. There are nearly 18 healthcare functions of the health food containing Gardeniae Fructus, and most of these are assisted functions to protect chemical liver injury, and then immune modulating function. Of 23 formulas containing Gardeniae Fructus having assisted function formula to protect chemical liver injury, Gardeniae Fructus usually combined with traditional Chinese medicine which nourishs blood and liver such as Pueraria, Lycii Fructus, Hawthorn, Paeonia and Turnjujube. Analyzing formula raw materials application of health food containing Gardeniae Fructus contributes a lot to the further development and utilization.

  20. Geometry of spinning Ellis wormholes

    NASA Astrophysics Data System (ADS)

    Chew, Xiao Yan; Kleihaus, Burkhard; Kunz, Jutta

    2016-11-01

    We give a detailed account of the properties of spinning Ellis wormholes, supported by a phantom field. The general set of solutions depends on three parameters, associated with the size of the throat, the rotation, and the symmetry of the solutions. For symmetric wormholes the global charges possess the same values in both asymptotic regions, while this is no longer the case for nonsymmetric wormholes. We present mass formulas for these wormholes, study their quadrupole moments, and discuss the geometry of their throat and their ergoregion. We demonstrate, that these wormholes possess limiting configurations corresponding to an extremal Kerr black hole. Moreover, we analyze the geodesics of these wormholes, and show that they possess bound orbits.

  1. Ellis-van Creveld syndrome.

    PubMed

    Sasalawad, Shilpa S; Hugar, Shivayogi M; Poonacha, K S; Mallikarjuna, Rachappa

    2013-07-09

    Ellis-van Creveld (EvC) syndrome or chondroectodermal dysplasia is an autosomal recessive disorder with characteristic clinical manifestations. The four principal characteristics are chondrodysplasia, polydactyly, ectodermal dysplasia and congenital heart defects. Its incidence in the general population is low. The oral manifestations of EvC syndrome include both soft tissues and teeth, but the dental literature on the subject is scarce. The present case describes the constant and variable oral findings in these patients, which can be diagnosed at any age, even during pregnancy. The presence of a variety of oral manifestations, such as fusion of upper lip to the gingival margin, presence of multiple frenula, abnormally shaped and microdontic teeth and congenitally missing teeth requires multidisciplinary dental treatment, with consideration for the high incidence of cardiac defects in these patients.

  2. Al Ellis: Up Close and Personal

    ERIC Educational Resources Information Center

    Eckstein, Daniel; Ellis, Debbie Joffe

    2011-01-01

    The purpose of the following article is to share some of the personal relationship comments and to provide a tribute to the significant 93 years that Albert Ellis lived and also make major contributions to the counseling profession.

  3. Ellis-van Creveld syndrome.

    PubMed

    Baujat, Geneviève; Le Merrer, Martine

    2007-06-04

    Ellis-van Creveld syndrome (EVC) is a chondral and ectodermal dysplasia characterized by short ribs, polydactyly, growth retardation, and ectodermal and heart defects. It is a rare disease with approximately 150 cases reported worldwide. The exact prevalence is unknown, but the syndrome seems more common among the Amish community. Prenatal abnormalities (that may be detected by ultrasound examination) include narrow thorax, shortening of long bones, hexadactyly and cardiac defects. After birth, cardinal features are short stature, short ribs, polydactyly, and dysplastic fingernails and teeth. Heart defects, especially abnormalities of atrial septation, occur in about 60% of cases. Cognitive and motor development is normal. This rare condition is inherited as an autosomal recessive trait with variable expression. Mutations of the EVC1 and EVC2 genes, located in a head to head configuration on chromosome 4p16, have been identified as causative. EVC belongs to the short rib-polydactyly group (SRP) and these SRPs, especially type III (Verma-Naumoff syndrome), are discussed in the prenatal differential diagnosis. Postnatally, the essential differential diagnoses include Jeune dystrophy, McKusick-Kaufman syndrome and Weyers syndrome. The management of EVC is multidisciplinary. Management during the neonatal period is mostly symptomatic, involving treatment of the respiratory distress due to narrow chest and heart failure. Orthopedic follow-up is required to manage the bones deformities. Professional dental care should be considered for management of the oral manifestations. Prognosis is linked to the respiratory difficulties in the first months of life due to thoracic narrowness and possible heart defects. Prognosis of the final body height is difficult to predict.

  4. 8. NORTH ELLIS WORKS LOOKING SOUTHWEST. BOTTLING HOUSE, RIGHT, FIVE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. NORTH ELLIS WORKS LOOKING SOUTHWEST. BOTTLING HOUSE, RIGHT, FIVE CHAMBER CONDENSER, AND BURIED NORTH ELLIS THREE PIPE INCLINED RETORT, BACKGROUND LEFT. - Mariscal Quicksilver Mine & Reduction Works, Terlingua, Brewster County, TX

  5. John A. Scigliano Interviews Allan B. Ellis.

    ERIC Educational Resources Information Center

    Scigliano, John A.

    2000-01-01

    This interview with Allan Ellis focuses on a history of computer applications in education. Highlights include work at the Harvard Graduate School of Education; the New England Education Data System; and efforts to create a computer-based distance learning and development program called ISVD (Information System for Vocational Decisions). (LRW)

  6. Ellie Mannette: Master of the Steel Drum.

    ERIC Educational Resources Information Center

    Svaline, J. Marc

    2001-01-01

    Presents an interview with Elliot ("Ellie") Mannette who has played a major role in the development and application of steel drums. States that he has spent most of his life designing and teaching the steel drums. Covers interview topics and background information on Mannette. (CMK)

  7. Remediation System Evaluation, Ellis Property Superfund Site

    EPA Pesticide Factsheets

    The Ellis Property Superfund Site is located in a rural area of Burlington County, New Jersey. Most ofthe land at the site has not been developed. However, there is a building in a fenced area that is used tohouse the remedial system..

  8. Bending of Light in Ellis Wormhole Geometry

    NASA Astrophysics Data System (ADS)

    Bhattacharya, Amrita; Potapov, Alexander A.

    A recent work by Dey and Sen derived the approximate light deflection angle α by an Ellis wormhole in terms of proper radial distance ℓ that covers the entire spacetime. On the other hand, Bodenner and Will calculated the expressions for light bending in Schwarzschild geometry using various coordinates and showed that they all reduce to a single formula when re-expressed in the coordinate independent language of "circumferential radius" rC identified with the standard radial coordinate rS. We shall argue that the coordinate invariant language for two-way wormholes should be ℓ rather than rS. Hence here we find the exact deflection α in Ellis wormhole geometry first in terms of ℓ and then in terms of rS. We confirm the latter expression using three different methods. We argue that the practical measurement scheme does not necessarily single out either ℓ or rS. Some errors in the literature are corrected.

  9. John Tracy Ellis and the Figure of the Catholic Intellectual

    ERIC Educational Resources Information Center

    Conniff, Brian

    2006-01-01

    Fifty years after John Tracy Ellis challenged the quality and character of Catholic intellectual life, much work remains to be done. This essay explores Ellis's original assertions and places them in an overarching historical context that involves Flannery O'Connor and Thomas Merton.

  10. Second Language Acquisition Research: A Response to Rod Ellis.

    ERIC Educational Resources Information Center

    Hopkins, Diana; Nettle, Mark

    1994-01-01

    Two practicing English-as-a-Foreign-Language (EFL teachers respond to Rod Ellis' January 1993 article in "ELT Journal," which discussed importance of grammar instruction in EFL classrooms. Argues some of Ellis' assumptions about current classroom practices are inaccurate and a number of his "alternative" approaches to teaching grammar, such as…

  11. GRAVITATIONAL MICROLENSING BY THE ELLIS WORMHOLE

    SciTech Connect

    Abe, F.

    2010-12-10

    A method to calculate light curves of the gravitational microlensing of the Ellis wormhole is derived in the weak-field limit. In this limit, lensing by the wormhole produces one image outside the Einstein ring and another image inside. The weak-field hypothesis is a good approximation in Galactic lensing if the throat radius is less than 10{sup 11} km. The light curves calculated have gutters of approximately 4% immediately outside the Einstein ring crossing times. The magnification of the Ellis wormhole lensing is generally less than that of Schwarzschild lensing. The optical depths and event rates are calculated for the Galactic bulge and Large Magellanic Cloud fields according to bound and unbound hypotheses. If the wormholes have throat radii between 100 and 10{sup 7} km, are bound to the galaxy, and have a number density that is approximately that of ordinary stars, detection can be achieved by reanalyzing past data. If the wormholes are unbound, detection using past data is impossible.

  12. Ellis-van Creveld syndrome and dyserythropoiesis.

    PubMed

    Scurlock, Deven; Ostler, Daniel; Nguyen, Andy; Wahed, Amer

    2005-05-01

    Ellis-van Creveld (EVC) syndrome or chondroectodermal dysplasia is a rare autosomal recessive disorder characterized by a variable spectrum of clinical findings. Classical EVC syndrome comprises a tetrad of clinical manifestations of chondrodystrophy, polydactyly, ectodermal dysplasia, and cardiac defects. In several case reports, dysplasia involving other organs has also been identified. Hematologic abnormalities have been rarely reported in patients with EVC syndrome. Here, we report a case of a 3-year-old Hispanic boy with EVC syndrome and marked dyserythropoiesis. The dyserythropoiesis may be part of an isolated myelodysplastic change or a primary myelodysplastic syndrome and likely represents an unusual EVC syndrome association. To our knowledge, this association has not been previously reported.

  13. Photovoltaic performance of TiO2 electrode adsorbed with gardenia yellow purified by nonionic polymeric sorbent in dye-sensitized solar cells.

    PubMed

    Kwon, Oh Oun; Kim, Eui Jin; Lee, Jae Hyeok; Kim, Tae Young; Park, Kyung Hee; Kim, Sang Yook; Suh, Hwa Jin; Lee, Hyo Jung; Lee, Jae Wook

    2015-02-05

    To improve the photovoltaic conversion efficiency in dye-sensitized solar cells (DSSCs), TiO2 electrode adsorbed with gardenia yellow purified by nonionic polymeric sorbent was successfully formulated on nanoporous TiO2 surface. Adsorption and desorption properties of crude gardenia yellow solution on a macroporous resin, XAD-1600, were investigated to purify gardenia yellow because of its strong adsorption and desorption abilities as well as high selectivity. To this end, adsorption equilibrium and kinetic data were measured and fitted using adsorption isotherms and kinetic models. Adsorption and desorption breakthrough curves in a column packed with XAD-1600 resin was obtained to optimize the separation process of gardenia yellow. The photovoltaic performance of the photo-electrode adsorbed with the crude and purified gardenia yellow in DSSCs was compared from current-voltage measurements. The results showed that the photovoltaic conversion efficiency was highly dependent on how to separate and purify gardenia yellow as a photosensitizer.

  14. 75. SACRED HEART SCHOOL, 1324 ELLIS STREET SOUTH (REAR ELEVATION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    75. SACRED HEART SCHOOL, 1324 ELLIS STREET SOUTH (REAR ELEVATION FROM GREENE STREET 56/61A - Greene Street Historic District, Greene Street, Gordon Highway to Augusta Canal Bridge, Augusta, Richmond County, GA

  15. 45. VIEW OF TWO ROOM STONE STRUCTURES BELOW ELLIS WORKS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    45. VIEW OF TWO ROOM STONE STRUCTURES BELOW ELLIS WORKS TAILINGS, ALONG ACCESS ROAD TO SITE LOOKING NORTHWEST. NOTICE OTHER STONE HOUSES ALONG RIDGE TO THE RIGHT. - Mariscal Quicksilver Mine & Reduction Works, Terlingua, Brewster County, TX

  16. 3. ELLIS WORKS PARTIALLY OBSCURED BY SUBSEQUENT MARISCAL ERA TAILINGS, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. ELLIS WORKS PARTIALLY OBSCURED BY SUBSEQUENT MARISCAL ERA TAILINGS, LOOKING SOUTH, SOUTHWEST. SAME VIEW AS HISTORICAL PHOTOGRAPH, BUREAU OF MINES BULLETIN 222. - Mariscal Quicksilver Mine & Reduction Works, Terlingua, Brewster County, TX

  17. VIEW OF TWO ROOM STONE STRUCTURES BELOW ELLIS WORKS TAILINGS, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF TWO ROOM STONE STRUCTURES BELOW ELLIS WORKS TAILINGS, ALONG ACCESS ROAD TO SITE LOOKING NORTHWEST. NOTICE OTHER STONE HOUSES ALONG RIDGE TO THE RIGHT. - Mariscal Quicksilver Mine & Reduction Works, Terlingua, Brewster County, TX

  18. ELLIS WORKS PARTIALLY OBSCURED BY SUBSEQUENT MARISCAL ERA TAILINGS, LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ELLIS WORKS PARTIALLY OBSCURED BY SUBSEQUENT MARISCAL ERA TAILINGS, LOOKING SOUTH, SOUTHWEST. SAME VIEW AS HISTORICAL PHOTOGRAPH, BUREAU OF MINES BULLETIN 222. - Mariscal Quicksilver Mine & Reduction Works, Terlingua, Brewster County, TX

  19. Ellis-van Creveld syndrome. Case report and literature review.

    PubMed

    Alves-Pereira, Daniela; Berini-Aytés, Leonardo; Gay-Escoda, Cosme

    2009-07-01

    Ellis-van Creveld syndrome is a genetic disorder that was first described by Richard Ellis and Simon van Creveld in 1940. The four principal characteristics are chondrodysplasia, polydactyly, ectodermal dysplasia and congenital heart defects. The orofacial manifestations include multiple gingivolabial musculofibrous fraenula, dental anomalies, hypodontia and malocclusion. The disease can be diagnosed at any age, even during pregnancy. The differentiation should be made between Jeune syndrome and other orofaciodigital syndromes.

  20. Magnetoplasmadynamcis - Portrait of Macon C. 'Mike' Ellis, Jr

    NASA Technical Reports Server (NTRS)

    1962-01-01

    Portrait of Macon C. 'Mike' Ellis, Jr. James Hansen described Mike Ellis as 'the first and only person to be in charge of Langley's Magnetoplasmadynamcis (MPD) Branch.' He was 'an NACA veteran who was 42 years old when the branch was organized. Ellis had come to work at Langley in 1939, and over the course of his career at the laboratory, he had been involved in pioneering work on the aerodynamics of jet engines, ramjets, and supersonic inlets and nozzles. Fittingly, Ellis had worked for Eastman Jacobs and with Arthur Kantrowitz in the early 1940s, and he had heard firsthand accounts of his former colleagues' attempts to design a fusion reactor in the spring of 1938. By the late 1950s, Ellis was one of Langley's most outspoken believers in MPD's promise of technological benefits. Ellis encouraged Floyd Thompson's enthusiasm for MPD and persuaded Langley's senior staff of mostly engineers that MPD was a field of research vital to the future of NASA. When the time came to pick someone to head the new branch, Ellis was unquestionably the person for the job. 'Ellis was no extraordinary 'scientific brain.' As an aeronautical engineer, his talents were quite respectable, but he possessed no special competency in the physics of fluids beyond his experience in aerodynamics or gas dynamics. He was always the first to admit that the complexities of plasma physics and MPD were such that 'there was no way' that he personally could conduct basic MPD research. That challenge he would leave to minds more suited for it. But Ellis could bring the MPD researchers together as a unit, serve as their strong external advocate, shield them from front-office pressures, and make sure that they received the support they needed to carry out their work. 'I just tried to keep my head above water,' Ellis explains, 'and keep these *mad scientists' from going off on too many tangents, or going mad myself.' Published in James R. Hansen, Spaceflight Revolution: NASA Langley Research Center From

  1. 77 FR 66979 - Ellis Road/American Electric Corporation, Jacksonville, Duval County, FL, Notice of Settlement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-08

    ... Ms. Paula V. Painter. Submit your comments by Site name Ellis Road/American Electric Corporation Site... over 80 settling parties at the Ellis Road/American Electric Corporation Superfund Site located...

  2. The action potential of Dionaea muscipula Ellis.

    PubMed

    Hodick, D; Sievers, A

    1988-04-01

    The intention of this investigation was to acquire more concise information about the nature of the action potential of Dionaea muscipula Ellis and the different types of cells generating and conducting it. It is shown by microelectrode measurements that, besides the sensory cells, all the major tissues of the trap lobes are excitable, firing action potentials with pronounced after-hyperpolarizations. The action potentials are strictly dependent on Ca(2+). Their peak depolarizations are shifted 25-27 mV in a positive direction after a tenfold increase in external Ca(2+) concentration. Perfusions with 1 mM ethylene glycol-bis(β-aminoethyl ether)-N,N,N',N'-tetraacetic acid (EGTA) or 1 mM LaCl3 completely inhibit excitability. Magnesium ions only slightly affect the peak depolarizations but considerably prolong action potentials. Sodium azide and 2,4-dinitrophenol also abolish excitation, probably by reducing the intracellular ATP concentration. Furthermore, it is tested whether the sensory cells can be distinguished from the other cells of the trap by their electrical behaviour. The resting potentials of sensory cells (-161±7 mV) and mesophyll cells (-155±8 mV) are of the same magnitude. Changes in external ion concentrations affect resting and action potentials in both cell types in a similar way. Additional freeze-fracture studies of both cell types reveal similar numbers and distributions of intramembrane particles on the fracture faces of the plasma membrane, which is most likely the mechanosensor. These findings stress the view that the high mechanosensitivity of the sensory hair results from its anatomy and not from a specialized perception mechanism. It is proposed that trap closure is triggered by a rise in the cytoplasmic concentration of Ca(2+) or a Ca(2+)-activated regulatory complex, which must exceed a threshold concentration. Since the Ca(2+) influx during a single action potential does not suffice to reach this threshold, at least two stimulations

  3. Metabolic profile of Fructus Gardeniae in human plasma and urine using ultra high-performance liquid chromatography coupled with high-resolution LTQ-orbitrap mass spectrometry.

    PubMed

    Wang, Gao-Wa; Bao, Burenbatu; Han, Zhi-Qiang; Han, Qing-Yu; Yang, Xiu-Lan

    2016-10-01

    1. In China, Fructus Gardeniae was used as a traditional Chinese medicine (TCM) with a wide array of biological activities. The bioactive components identified in Fructus Gardeniae mainly included iridoids, flavonids, pigments, and so on. Among them, iridoids were regarded as important compounds in Fructus Gardeniae. Though analyses of the constituents in biological samples after oral administration of Fructus Gardeniae effective fraction or its active compounds have been reported, few efforts have been made to investigate the metabolic profile of Fructus Gardeniae in humans. In this study, the constituents and metabolites of Fructus Gardeniae in human blood and urine after oral administration of Fructus Gardeniae were investigated using ultra high-performance liquid chromatography (UHPLC) coupled with high-resolution LTQ-Orbitrap mass spectrometery. 2. Totally, 14 constituents (two parent compounds and 12 metabolites) of Fructus Gardeniae were identified in human plasma and urine either by comparing the retention time and mass spectrometry data with that of reference compounds or by the accurate high-resolution MS/MS data of the chemicals. The compounds identified were mainly iridoid glycosides such as geniposide and the derivatives of genipin-O-glucuronide. Among them, 11 metabolites were detected in human plasma and urine while the other three metabolites including geniposidic acid (M1), demethylation derivative of genipin-O-glucuronide (M2), and dehydration product of mono-hydroxylated genipin-O-glucuronide (M9) were only discovered in human urine. Further, the possible metabolic pathways of Fructus Gardeniae in vivo were proposed and the peak area-time curve of the most abundant metabolite genipin-O-glucuronide (M13) in human plasma after oral administration of Fructus Gardeniae was depicted. The results suggested that a metabolic difference existed between rats and humans. 3. The results obtained in the present research would provide basic information to

  4. Havelock Ellis's literary criticism, canon formation, and the heterosexual Shakespeare.

    PubMed

    Radel, Nicholas F

    2009-01-01

    Famous as the author of an early full-length scientific study of sexual inversion or homosexuality, English sexologist Havelock Ellis was also a literary critic responsible for initiating publication of the famous Mermaid Series of "The Best of Plays of the Old Dramatists" in the late-nineteenth century. Personally editing the first volume of plays by Christopher Marlowe and a later collection by tragedian John Ford, Ellis associated these playwrights here and in his scientific work, Sexual Inversion, with ideas about normative and so-called abnormal sexualities at the start of the twentieth century. Ellis, thus, helped give expression to a literary canon of early English dramatists in which modern, anachronistic ideas about sexual subjectivity play a part. While this article does not claim that Ellis was the necessary source for later criticism, it shows how, over the whole of the twentieth century, Shakespeare's priority in the literary canon came to be posited at least in part on his apparent sexual normality in contrast with a supposedly homosexual Christopher Marlowe and other playwrights such as Ford or Francis Beaumont and John Fletcher associated with varying degrees of sexual difference.

  5. Courseware Reviews: ELLIS Opens a Doorway to English.

    ERIC Educational Resources Information Center

    Crawford, William

    1994-01-01

    Overviews ELLIS, a computer software program that is an individualized English language learning system using computer technology to integrate video disk, CD-ROM, and computer storage to display and manipulate video, audio, text, and graphic information. Although its strength lies in its individual multimedia approach to language learning, ELLIS…

  6. Ellis Island and the Peopling of America: The Official Guide.

    ERIC Educational Resources Information Center

    Yans-McLaughlin, Virginia; Lightman, Marjorie

    This guide book helps to place the Ellis Island Museum (New York) and site within the context of the worldwide, continuing history of immigration. The guide views immigration as a continuing social process that brings people from one part of the world to another where they contribute the richness of their labor to their newly adopted home. Ethnic…

  7. Let's Nuke the Transpersonalists: A Response to Albert Ellis.

    ERIC Educational Resources Information Center

    Wilber, Ken

    1989-01-01

    Responds to Albert Ellis' 1986 article which proposed to use rational-emotive therapy (RET) to save the world from religious and psychological fanatics and nuclear war. Attempts to provide a more balanced view of religion, RET, non-RET therapies, and the role of psychology in averting nuclear war. (Author/ABL)

  8. Oral abnormalities in the Ellis-van Creveld syndrome.

    PubMed

    Babaji, Prashant

    2010-01-01

    Ellis-van Creveld (EvC) syndrome is an autosomal recessive disorder, mainly affecting the ectodermal components such as, enamel, nail, and hair. The gene for EvC syndrome is located on chromosome 4p16. Patients with EvC syndrome characteristically presents with congenitally missing teeth, abnormal frenal attachment, microdontia, and hexadactyly.

  9. Albert Ellis Revisited: Vague, General or Mild Religion.

    ERIC Educational Resources Information Center

    Floyd, William A.

    1984-01-01

    Discusses the writings of Albert Ellis dealing with religion and psychotherapy. Advocates a liberal form of theism in which (1) the use of symbolism and ritual are stressed; (2) faith is taken seriously but not as history or science; and (3) the importance of theology is affirmed. (JAC)

  10. Gravity-Driven Thin Film Flow of an Ellis Fluid.

    PubMed

    Kheyfets, Vitaly O; Kieweg, Sarah L

    2013-12-01

    The thin film lubrication approximation has been studied extensively for moving contact lines of Newtonian fluids. However, many industrial and biological applications of the thin film equation involve shear-thinning fluids, which often also exhibit a Newtonian plateau at low shear. This study presents new numerical simulations of the three-dimensional (i.e. two-dimensional spreading), constant-volume, gravity-driven, free surface flow of an Ellis fluid. The numerical solution was validated with a new similarity solution, compared to previous experiments, and then used in a parametric study. The parametric study centered around rheological data for an example biological application of thin film flow: topical drug delivery of anti-HIV microbicide formulations, e.g. hydroxyethylcellulose (HEC) polymer solutions. The parametric study evaluated how spreading length and front velocity saturation depend on Ellis parameters. A lower concentration polymer solution with smaller zero shear viscosity (η0), τ1/2, and λ values spread further. However, when comparing any two fluids with any possible combinations of Ellis parameters, the impact of changing one parameter on spreading length depends on the direction and magnitude of changes in the other two parameters. In addition, the isolated effect of the shear-thinning parameter, λ, on the front velocity saturation depended on τ1/2. This study highlighted the relative effects of the individual Ellis parameters, and showed that the shear rates in this flow were in both the shear-thinning and plateau regions of rheological behavior, emphasizing the importance of characterizing the full range of shear-rates in rheological measurements. The validated numerical model and parametric study provides a useful tool for future steps to optimize flow of a fluid with rheological behavior well-described by the Ellis constitutive model, in a range of industrial and biological applications.

  11. Gravitational Microlensing by Ellis Wormhole: Second Order Effects

    NASA Astrophysics Data System (ADS)

    Lukmanova, Regina; Kulbakova, Aliya; Izmailov, Ramil; Potapov, Alexander A.

    2016-11-01

    Gravitational lensing is the effect of light bending in a gravitational field. It can be used as a possible observational method to detect or exclude the existence of wormholes. In this work, we extend the work by Abe on gravitational microlensing by Ellis wormhole by including the second order deflection term. Using the lens equation and definition of Einstein radius, we find the angular locations of the physical image inside and outside Einstein ring. The work contains a comparative analysis of light curves between the Schwarzschild black hole and the Ellis wormhole that can be used to distinguish such objects though such distinctions are too minute to be observable even in the near future. We also tabulate the optical depth and event rate for lensing by bulge and Large Magellanic Cloud (LMC) stars.

  12. Rational Emotive Behavioural Therapy: The Evolution of a Revolution: Interview With Dr. Debbie Joffe Ellis, Work Partner and Wife of Dr. Albert Ellis, the Creator of REBT.

    PubMed

    Ellis, Debbie Joffe; Rovira, Montse

    2015-02-01

    Recognized as one of the most influential thinkers and psychologists, Albert Ellis PhD (1913-2007) revolutionized Psychology when he created the first cognitive psychotherapy, Rational Emotive Behavioral Therapy. After he passed away, Dr. Debbie Joffe Ellis continues spreading his legacy around the world. Psychologist, lecturer, writer, trainer, she dedicates her life to disseminate REBT and extend it through different statements, from the social to the educational, from the academic to the clinical. In this interview, she goes through her own history and her husband's one, bringing us closer to understanding Albert Ellis as the leading figure in his field, and the oneness they experienced through their professional and personal relationship.

  13. [Analysis of headspace constituents of Gardenia flower by GC/MS with solid-phase microextraction and dynamic headspace sampling].

    PubMed

    Liu, B Z; Gao, Y

    2000-09-01

    The headspace constituents of fresh Gardenia flower were investigated by GC/MS. The headspace volatiles were sampled by solid-phase microextraction (SPME) and dynamic headspace sampling (DHS). SPME sampling was conducted with 100 microns PDMS fiber at 28 degrees C for 60 min. In DHS sampling, purified nitrogen was used as purging gas with a flow rate at 80 mL/min for 120 min. Tenax GR(20 mesh-40 mesh) was used as adsorbent and the volatiles were eluted by ether, and concentrated to 0.5 mL for GC/MS analysis. A Supelco-wax capillary column (30 m x 0.25 mm i.d. x 0.25 micron df) was employed in GC/MS analysis. Initial oven temperature was kept at 45 degrees C for 2 min, then raised to 250 degrees C at 4 degrees C/min, and kept at 250 degrees C for 10 min. According to SPME-GC/MS analysis, the main compounds in headspace of fresh Gardenia flower included farnesene(64.86%), cis-ocimene(29.33%), linalool(2.74%), cis-3-hexenyl tiglate(1.34%), methyl benzoate(0.25%). Results obtained from SPME and DHS sampling were also compared. In this study, SPME afforded a simpler and more sensitive sampling method, and much more accurate information about headspace volatiles of Gardenia flower.

  14. Layered co-sensitization of gardenia and monascus for panchromatic light harvesting in dye-sensitized solar cells

    NASA Astrophysics Data System (ADS)

    Kwon, Oh Oun; Lee, Hyo Jung; Kim, Sang-Wook; Kim, Jung-Hun; Kim, Tae-Young; Park, Kyung-Hee; Lee, Jae-Wook

    2015-04-01

    TiO2 electrodes adsorbed with two natural dyes (gardenia yellow and monascus) were used as sensitizers to improve the conversion efficiency of cocktail dye-sensitized solar cells (CDSC) for light harvesting over a wide range of wavelength. Adsorption and electrochemical properties of two dyes were evaluated based on adsorption kinetics and electrochemical measurements. In addition, the photovoltaic performance of a photo-electrode adsorbed with single-dye (gardenia yellow and monascus) or the mixture or successive adsorption of the two dyes, was evaluated from current-voltage measurements. Layered co-sensitization of the two natural dyes was compared depending on the adsorption modes. As for the TiO2 electrode with successive adsorption of monascus and gardenia yellow dyes, the solar cell yields a short-circuit current density (Jsc) of 2.04 mA/cm2, a photovoltage (Voc) of 0.63 V, and a fill factor of 0.64, corresponding to an energy conversion efficiency (η) of 0.82%.

  15. ESTCP Munitions Response: Live Site Demonstration Former Camp Ellis

    DTIC Science & Technology

    2014-07-01

    encompassed 17,455 acres and had more than 2,300 buildings, 1,100 of which were coal- heated barracks. Camp Ellis trained a wide variety of soldiers for...1 – The coordinates are provided in UTM Zone 15N World Geodetic System 84, with units of meters. Figure 5-2: IVS Layout All items were...following benefits:  The forklift had a heated cab in which the field technician sat during data collection. CEMR was conducted in winter, so the

  16. Deflection angle of light in an Ellis wormhole geometry

    NASA Astrophysics Data System (ADS)

    Nakajima, Koki; Asada, Hideki

    2012-05-01

    We reexamine the light deflection by an Ellis wormhole. The bending angle as a function of the ratio between the impact parameter and the throat radius of the wormhole is obtained in terms of a complete elliptic integral of the first kind. This result immediately yields asymptotic expressions in the weak field approximation. It is shown that an expression for the deflection angle derived (and used) in recent papers is valid at the leading order but it breaks down at the next order because of the nontrivial spacetime topology.

  17. Ellis-van Creveld Syndrome with Sagittal Craniosynostosis.

    PubMed

    Fischer, Andrew S; Weathers, William M; Wolfswinkel, Erik M; Bollo, Robert J; Hollier, Larry H; Buchanan, Edward P

    2015-06-01

    Ellis-van Creveld syndrome (EVC) is a rare disorder (the incidence is estimated at around 7/1,000,000) characterized by the clinical tetrad of chondrodystrophy, polydactyly, ectodermal dysplasia, and cardiac anomalies. Sagittal synostosis is characterized by a dolichocephalic head shape resulting from premature fusion of the sagittal suture. Both are rare disorders, which have never been reported together. We present a case of EVC and sagittal synostosis. We report the clinical features of a Hispanic boy with EVC and sagittal craniosynostosis who underwent cranial vault remodeling. The presentation of this patient is gone over in detail. A never before reported case of EVC and sagittal synostosis is presented in detail.

  18. Ellis-van Creveld syndrome: A rare clinical entity

    PubMed Central

    Kamal, Reet; Dahiya, Parveen; Kaur, Simerpreet; Bhardwaj, Rohit; Chaudhary, Karun

    2013-01-01

    Ellis-van Creveld (EVC) syndrome is a genetic disorder with autosomal recessive transmission, which may clinically present as small stature, short limbs, fine sparse hair, hypoplastic fingernails, multiple musculofibrous frenula, conical teeth, hypoplasia of the enamel, hypodontia, and malocclusion. Heart defects, especially abnormalities of atrial septation, have been found in about 60% of cases. The mutation in EVC and EVC2 gene is responsible for this syndrome. The presence of multiple orodental findings makes this syndrome important for dentists. The aim of this article is to present a rare case of EVC syndrome in a 10-year-old girl along with the review of literature. PMID:23798848

  19. Ellis-van Creveld syndrome with facial hemiatrophy.

    PubMed

    Bhat, Yasmeen J; Baba, Asif Nazir; Manzoor, Sheikh; Qayoom, Seema; Javed, Sheikh; Ajaz, Hakeem

    2010-01-01

    Ellis-van Creveld (EVC) syndrome is a rare autosomal recessive congenital disorder characterized by chondrodysplasia and polydactyly, ectodermal dysplasia and congenital defects of the heart. We present here a case of a 16-year-old short-limbed dwarf with skeletal deformities and bilateral postaxial polydactyly, dysplastic nails and teeth, also having left-sided facial hemiatrophy. The diagnosis of EVC syndrome was made on the basis of clinical and radiological features. To the best of our knowledge, this is the first report of EVC syndrome with facial hemiatrophy in the medical literature from India.

  20. Ellis-van Creveld syndrome: A rare clinical entity.

    PubMed

    Kamal, Reet; Dahiya, Parveen; Kaur, Simerpreet; Bhardwaj, Rohit; Chaudhary, Karun

    2013-01-01

    Ellis-van Creveld (EVC) syndrome is a genetic disorder with autosomal recessive transmission, which may clinically present as small stature, short limbs, fine sparse hair, hypoplastic fingernails, multiple musculofibrous frenula, conical teeth, hypoplasia of the enamel, hypodontia, and malocclusion. Heart defects, especially abnormalities of atrial septation, have been found in about 60% of cases. The mutation in EVC and EVC2 gene is responsible for this syndrome. The presence of multiple orodental findings makes this syndrome important for dentists. The aim of this article is to present a rare case of EVC syndrome in a 10-year-old girl along with the review of literature.

  1. 75 FR 38768 - Rehabilitation of Floodwater Retarding Structure No. 10 of the Mountain Creek Watershed, Ellis...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-06

    ... Floodwater Retarding Structure No. 10 of the Mountain Creek Watershed, Ellis County, TX AGENCY: Natural.... 10 of the Mountain Creek Watershed, Ellis County, Texas. FOR FURTHER INFORMATION CONTACT: Donald W... project. The project will rehabilitate Floodwater Retarding Structure No. 10 to maintain the present...

  2. Synthesis of porous starch xerogels modified with mercaptosuccinic acid to remove hazardous gardenia yellow.

    PubMed

    Bao, Liping; Zhu, Xinyi; Dai, Hongxia; Tao, Yongxin; Zhou, Xiaoying; Liu, Wenjie; Kong, Yong

    2016-08-01

    Mercaptosuccinic acid (MSA) molecules were inserted into potato starch, leading to the breaking of intrinsic H-bonds within macromolecular chains of starch and the formation of intermolecular H-bonds between MSA and starch, which could be verified by Fourier transform infrared spectroscopy (FT-TR). MSA modified porous starch xerogels (PSX/MSA) were obtained after freeze-drying the MSA modified starch, and they were characterized by field emission scanning electron microscopy (FESEM), exhibiting the intriguing porous structure due to the separation of starch chains by MSA molecules. The PSX/MSA were then used as the adsorbents to remove gardenia yellow (GY), a natural colorant with genotoxicity. Due to the porous structure of PSX and the introduced carboxyl groups from MSA, the adsorption capacity of the PSX/MSA was much higher than that of the starch xerogels alone (SX). The adsorption behaviors of GY by the PSX/MSA fitted both the Freundlich isotherm model and the pseudo-second-order kinetic model, and the efficient adsorption of GY suggested that the PSX/MSA might be potential adsorbents for the removal of dyes from contaminated aquatic systems.

  3. Ellis-van Creveld Syndrome: Mutations Uncovered in Lebanese Families.

    PubMed

    Valencia, Maria; Tabet, Lara; Yazbeck, Nadine; Araj, Alia; Ruiz-Perez, Victor L; Charaffedine, Khalil; Fares, Farah; Badra, Rebecca; Farra, Chantal

    2015-01-01

    Background. Ellis-van Creveld (EvC) syndrome is a rare, autosomal recessive disorder characterized by short stature, short limbs, growth retardation, polydactyly, and ectodermal defects with cardiac anomalies occurring in around 60% of cases. EVC syndrome has been linked to mutations in EVC and EVC2 genes. Case Presentation. We report EvC syndrome in two unrelated Lebanese families both having homozygous mutations in the EVC2 gene, c.2653C>T (p.(Arg885(*))) and c.2012_2015del (p.(Leu671(*))) in exons 15 and 13, respectively, with the latter being reported for the first time. Conclusion. Although EvC has been largely described in the medical literature, clinical features of this syndrome vary. While more research is required to explore other genes involved in EvC, early diagnosis and therapeutic care are important to achieve a better quality of life.

  4. Ellis-van Creveld syndrome: a case report.

    PubMed

    Shah, B; Ashok, L; Sujatha, G P

    2008-01-01

    Ellis-van Creveld syndrome (EvC) is a disease complex, where all the three embryonic layers appear to be involved. This disorder is also called as Chondroectodermal dysplasia. EvC is an autosomal recessive disorder resulting from mutations in these patients. Mutations in the two genes EVC and EVC2, have been identified to cause the condition. It has been considered as a skeletal dysplasia with an incidence of approximately 1 out of 1,50,000 live births. A high prevalence has been reported among certain populations like Amish and Arabs of Gaza strip. There are more than 300 cases of EvC reported into the literature. About 50-60% of cases have been reported with congenital cardiac malformations.

  5. Rational emotive therapy-a study of initial therapy sessions of Albert Ellis.

    PubMed

    Becker, I M; Rosenfeld, J G

    1976-10-01

    Because psychotherapy is what a therapist does, and not necessarily what he says he does, it is important to observe the activity of leaders in the field during their sessions. Twenty taped initial psychotherapy sessions by Albert Ellis were selected randomly from 70 recently recorded ones. Typescripts of each session were made, and two raters naive to the purposes were trained to place each of Ellis' statements into 1 of 17 categories. Each category consisted of a therapeutic technique. Some of these were ones that Ellis did during the 20 sessions examined was related very closely to what he has claimed to do, but that he did vary considerably from client to client.

  6. Anti-inflammatory effects of β-sitosterol-β-D-glucoside from Trachelospermum jasminoides (Apocynaceae) in lipopolysaccharide-stimulated RAW 264.7 murine macrophages.

    PubMed

    Choi, Ji Na; Choi, Yun-Hyeok; Lee, Jeong-Min; Noh, Ill Chan; Park, Jae Won; Choi, Wahn Soo; Choi, Jung Ho

    2012-01-01

    Trachelospermum jasminoides (Apocynaceae) has pharmacological effects that include anti-inflammatory, anti-bacterial and anti-viral activities, which have been observed from various studies. Of these pharmacological effects, the anti-inflammatory capacity of compounds from T. jasminoides is not yet known exactly. In this study, we investigated the compound that can be used for the suppression of lipopolysacchaide (LPS) stimulated inflammatory responses in macrophages among the five isolated compounds. β-sitosterol-β-D-glucoside (1) was found to reduce nitric oxide (NO) production from LPS-induced RAW 264.7 cells the most. In addition, compound 1 strongly inhibited the interleukin 6 (IL-6) activities of stimulated macrophages. Treatment of RAW 264.7 cells with compound 1 reduced secretion of inflammatory elements including tumour necrosis factor - alpha (TNF-α) and interleukin 1 beta (IL-1β). Thus, compound 1 may be a useful candidate for the development of new drugs to treat endotoxemia and inflammation accompanied by the overproduction of NO.

  7. [Optimization of vacuum belt drying process of Gardeniae Fructus in Reduning injection by Box-Behnken design-response surface methodology].

    PubMed

    Huang, Dao-sheng; Shi, Wei; Han, Lei; Sun, Ke; Chen, Guang-bo; Wu Jian-xiong; Xu, Gui-hong; Bi, Yu-an; Wang, Zhen-zhong; Xiao, Wei

    2015-06-01

    To optimize the belt drying process conditions optimization of Gardeniae Fructus extract from Reduning injection by Box-Behnken design-response surface methodology, on the basis of single factor experiment, a three-factor and three-level Box-Behnken experimental design was employed to optimize the drying technology of Gardeniae Fructus extract from Reduning injection. With drying temperature, drying time, feeding speed as independent variables and the content of geniposide as dependent variable, the experimental data were fitted to a second order polynomial equation, establishing the mathematical relationship between the content of geniposide and respective variables. With the experimental data analyzed by Design-Expert 8. 0. 6, the optimal drying parameter was as follows: the drying temperature was 98.5 degrees C , the drying time was 89 min, the feeding speed was 99.8 r x min(-1). Three verification experiments were taked under this technology and the measured average content of geniposide was 564. 108 mg x g(-1), which was close to the model prediction: 563. 307 mg x g(-1). According to the verification test, the Gardeniae Fructus belt drying process is steady and feasible. So single factor experiments combined with response surface method (RSM) could be used to optimize the drying technology of Reduning injection Gardenia extract.

  8. Growth charts for children with Ellis-van Creveld syndrome.

    PubMed

    Verbeek, Sabine; Eilers, Paul H C; Lawrence, Kate; Hennekam, Raoul C M; Versteegh, Florens G A

    2011-02-01

    Ellis-van Creveld (EvC) syndrome is a congenital malformation syndrome with marked growth retardation. In this study, specific growth charts for EvC patients were derived to allow better follow-up of growth and earlier detection of growth patterns unusual for EvC. With the use of 235 observations of 101 EvC patients (49 males, 52 females), growth charts for males and females from 0 to 20 years of age were derived. Longitudinal and cross-sectional data were collected from an earlier review of growth data in EvC, a database of EvC patients, and from recent literature. To model the growth charts, the GAMLSS package for the R statistical program was used. Height of EvC patients was compared to healthy children using Dutch growth charts. Data are presented both on a scale for age and on a scale for the square root of age. Compared to healthy Dutch children, mean height standard deviation score values for male and female EvC patients were -3.1 and -3.0, respectively. The present growth charts should be useful in the follow-up of EvC patients. Most importantly, early detection of growth hormone deficiency, known to occur in EvC, will be facilitated.

  9. Bioavailability and brain-targeting of geniposide in gardenia-borneol co-compound by different administration routes in mice.

    PubMed

    Lu, Yang; Du, Shouying; Bai, Jie; Li, Pengyue; Wen, Ran; Zhao, Xuejiao

    2012-11-01

    Both geniposide (Ge) and borneol (Bo) are bioactive substances derived from traditional Chinese medicine. Injections containing co-compound of Gardenia-Borneol are widely used for stroke treatment in China, such as "Xingnaojing" multi-component injection. As more and more adverse reactions (especially drug allergy) were reported, it is urgent to find more effective and safer routes of administration for such kinds of medicines. In this paper, bioavailabilities and brain-target effects of geniposide in Gardenia-Borneol co-compound through different administration routes in mice were investigated. Geniposide concentrations in plasma and in brain of mice were determined by reversed-phase high-performance liquid chromatography. The pharmacokinetics parameters of intranasal (i.n.) and intragastric (i.g.) administration were compared with intravenous (i.v.) administration. The bioavailabilities of Ge were 85.38% and 28.76% for i.n. and i.g. while T(max) were 1 min and 30 min. C(max) were 21.881 ± 5.398, 1.914 ± 0.327 and 42.410 ± 6.268 μg/mL for i.n., i.g. and i.v., respectively. The AUC of Ge in brain were 32413.6 ± 4573.9, 6440.1 ± 863.7 and 37270.5 ± 4160.6 ng/g ·min for i.n., i.g. and i.v., respectively. The drug target indexes (DTI) were 1.02 and 0.60 for i.n. and i.g. The results demonstrated that geniposide could be absorbed promptly and thoroughly by i.n. administration in mice and basically transported into the brain though blood vessel passways.

  10. Research on the change of chemical composition in productive process of Re Du Ning injection by HPLC/Q-TOF MS.

    PubMed

    Zhang, Shan; Li, Yan-Jing; Zhang, Chun-Xiao; Huang, Wen-Zhe; Ding, Gang; Wang, Zhen-Zhong; Bi, Yu-An; Xiao, Wei

    2016-02-01

    A high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (HPLC/Q-TOF MS) was developed for the analysis of chemical composition change in the production process of Re Du Ning injection, a Chinese medicine preparation with a combination of Lonicera japonica Thunb., Gardenia jasminoides Ellis and Artemisia annua L. A total of 90 compounds from raw materials-intermediates-Re Du Ning injection were detected; among them, 55 compounds were identified or tentatively characterized, and the characteristic ions of different types of compounds were described. Based on these studies, the different types of compounds in the various process routes were analyzed. A total of 28 compounds, including seven iridoid glycosides and six monoterpenes from G. jasminoides Ellis, five iridoid glycosides, nine phenolic acids and one unknown compound from L. japonica Thunb., were transferred to Re Du Ning injection, and two unknown compounds were generated in the production process of Re Du Ning injection. The results indicated that the Chinese Medicine Pharmaceutical process control is very important. This method could provide some reference for other Chinese medicine preparations.

  11. Differential induction of the expression of GST subunits by geniposide in rat hepatocytes.

    PubMed

    Kuo, Wu-Hsien; Wang, Chau-Jong; Young, Shun-Chieh; Sun, Yuan-Chang; Chen, Yi-Jun; Chou, Fen-Pi

    2004-01-01

    Geniposide, an iridoid glycoside isolated from the fruit of Gardenia jasminoides Ellis, has the biological capabilities of detoxication, antioxidation, and anticarcinogenesis. In this study, the mechanism of geniposide affecting the GST (glutathione S-transferase) system was investigated. Primary cultured rat hepatocytes were treated with geniposide and examined for total GST activity and expression of GST subunits. The results showed that the geniposide-induced GST activity was dose and time dependent. Western blotting data demonstrated that geniposide induced increased protein levels of GSTM1 and GSTM2 (approximately 1.7- and 1.8-fold of control, respectively), but did not increase those of GSTA1. The corresponding transcripts levels were confirmed by RT-PCR. Using PD98059, the effect of geniposide was verified to be via the MEK pathway. The results suggest that geniposide possesses a potential for detoxication by inducing GST activity via increasing the transcription of GSTM1 and GSTM2.

  12. Welcome Home Annie: Rethinking Ellis Island and Annie Moore in the Classroom

    ERIC Educational Resources Information Center

    Mercurio, Mia

    2008-01-01

    The story of the United States and the people who have made it their home would not be complete without considering the experience of Irish immigrants--particularly the experience of Annie Moore, the first immigrant to be processed on Ellis Island. However, the story of Annie Moore, and how it has been recounted and taught to date, is inaccurate.…

  13. Overgeneralization from a Narrow Focus: A Response to Ellis et al. (2008) and Bitchener (2008)

    ERIC Educational Resources Information Center

    Xu, Cuiqin

    2009-01-01

    This paper presents a critical analysis of two recent studies on error correction, Ellis, Sheen, Murakami, and Takashima (2008) and Bitchener (2008) and argues that neither study constitutes evidence for error correction based on discussion of the comparability of participants, design issues, and analysis flaws in both studies. The paper further…

  14. Ellis van Creveld Syndrome (EVCS) in an Iranian, Three-Year-old Girl: A Case Report.

    PubMed

    Ehsan, Alaee; Ali, Shirafkan; Reihane, Hasheminejad; Deilami, Tourisa; Kia, Alireza

    2014-10-01

    Ellis van Creveld syndrome (EVCS) is mainly characterized by dysplatic changes in skeletal structures along with variable inter- and intra-familial patterns. Shortening of bony structures such as ribs and limbs, postaxial polydactyly, and dysplastic teeth and nails are among the clinical presentation of this autosomal recessive disease.

  15. The Importance of Voice in Supervision: A Response to Ellis and Robbins (1993) and Bernstein (1993).

    ERIC Educational Resources Information Center

    Twohey, Denise

    1993-01-01

    Comments two responses to author's article "Listening for the Voices of Care and Justice in Counselor Supervision" (Twohey and Volker, 1993). Responds to Ellis and Robbins (1993) by clarifying perspective on relationship between moral decision making and supervision. Takes issue with Bernstein's (1993) comments about superiority of instrumental…

  16. Productive and Reproductive Work on the Family Farm: Changes Among Ethnic Groups in Ellis County, Kansas.

    ERIC Educational Resources Information Center

    Flora, Cornelia Butler; Stitz, John

    This report is based on data obtained from historical documents, quantitative analysis of state agricultural censuses for 1885, 1895, and 1905, and interviews with farm women of Volga and German heritages, aged 14 to 87. The participation of women in wheat-based farming systems in Ellis County, Kansas, is examined as related to the ethnic…

  17. Re-Imagining Possibilities: Honoring the Work of Carolyn Ellis and Art Bochner

    ERIC Educational Resources Information Center

    Santoro, Patrick; Boylorn, Robin M.

    2008-01-01

    As co-chairs of a tribute panel for their academic mentors, Carolyn Ellis and Art Bochner, the authors knew what the traditional responsibilities would require, but as a performer and a poet, they were inspired to do something more creative. Something poetic. Something performative. Something different. In this article, the authors present a…

  18. Preventive effect of crocin in inflamed animals and in LPS-challenged RAW 264.7 cells.

    PubMed

    Xu, Guang-Lin; Li, Guang; Ma, Hua-Ping; Zhong, Hai; Liu, Fei; Ao, Gui-Zhen

    2009-09-23

    Gardenia jasminoides Ellis and Crocus sativus L. are both traditional Chinese medicines that have significant biologic activities on inflammatory processes. But the active ingredients remain unclear. Crocin, a representative of carotenoid compounds, has now drawn considerable attention not only because it is a natural food colorant but also because it has great potential in medicine. But until now, the systematic anti-inflammatory effect of crocin has not been well established. In the present study, experiments were carried out to evaluate the anti-inflammatory effects of crocin in vitro and in vivo. In vitro, cyclooxygenase (COX) inhibition assays showed that crocin exhibits a dual inhibitory activity against the COX-1 and COX-2 enzymes. Anti-inflammatory activity in vivo was evaluated using two animal edema model tests. Pretreatment with crocin (p.o.) dose-dependently inhibited the xylene-induced ear edema in mice and carrageenan-induced paw edema in rats. In gastric lesion tests, crocin was gastric-sparing in that it elicited markedly fewer stomach lesions as compared to the number of stomach lesions caused by indomethacin in rats. In further studies, crocin was found to significantly inhibit the productions of prostaglandin E(2) (PGE(2)) in lipopolysaccharide (LPS)-challenged RAW 264.7, which is parallel to its prevention of the nuclear translocation of the NF-kappaB p50 and p65 subunits. These data indicate that crocin exhibits obvious anti-inflammatory effects and may be one of the active ingredients in Gardenia jasminoides Ellis or Crocus sativus L. that can modulate inflammatory processes.

  19. Stability and instability of Ellis and phantom wormholes: Are there ghosts?

    NASA Astrophysics Data System (ADS)

    Nandi, K. K.; Potapov, A. A.; Izmailov, R. N.; Tamang, A.; Evans, J. C.

    2016-05-01

    It is concluded in the literature that the Ellis wormhole is unstable under small perturbations and would either decay to the Schwarzschild black hole or expand away to infinity. While this deterministic conclusion of instability is correct, we show that the Ellis wormhole reduces to the Schwarzschild black hole only when the Ellis solution parameter γ assumes a complex value -i . We shall then reexamine the stability of Ellis and phantom wormholes from the viewpoint of local and asymptotic observers by using a completely different approach, viz., we adapt Tangherlini's nondeterministic, prequantal statistical simulation about photon motion in the real optical medium to an effective medium reformulation of motions obtained via Hamilton's optical-mechanical analogy in a gravity field. A crucial component of Tangherlini's idea is the observed increase of momentum of the photons entering a real medium. We show that this fact has a heuristic parallel in the effective medium version of the Pound-Rebka experiment in gravity. Our conclusion is that there is a nonzero probability that Ellis and phantom wormholes could appear stable or unstable depending on the location of observers and on the values of γ , leading to the possibility of ghost wormholes (like ghost stars). The Schwarzschild horizon, however, would always certainly appear to be stable (R =1 , T =0 ) to observers regardless of their location. Phantom wormholes of bounded mass in the extreme limit a →-1 are also shown to be stable just as the Schwarzschild black hole is. We shall propose a thought experiment showing that our nondeterministic results could be numerically translated into observable deterministic signatures of ghost wormholes.

  20. Application of Scutellariae radix, Gardeniae fructus, and Probiotics to Prevent Salmonella enterica Serovar Choleraesuis Infection in Swine

    PubMed Central

    Chang, Chiung-Hung; Chen, Yueh-Sheng; Chiou, Ming-Tang; Su, Chiu-Hsian; Chen, Daniel S.; Tsai, Chin-En; Yu, Bi; Hsu, Yuan-Man

    2013-01-01

    Salmonella enterica serovar Choleraesuis, a host-adapted pathogen of swine, usually causes septicemia. Lactic acid bacteria (LAB) strains have been widely studied in recent years for their probiotic properties. In this study, a mouse infection model first screened for potential agents against infection, then a pig infection model evaluated effects of LAB strains and herbal plants against infection. Scutellariae radix (SR) and Gardeniae fructus (GF) showed abilities to reduce bacteria shedding and suppressing serum level of TNF-α induced by infection in swine. Bioactivities of SR and GF were enhanced by combining with LAB strains, which alone could speed up the bacteria elimination time in feces and boost immunity of infected pigs. Baicalein and genipin exhibited stronger cytotoxicity than baicalin and geniposide did, as well as prevent Salmonella from invading macrophages. Our study suggests LAB strains as exhibiting multiple functions: preventing infection, enhancing immunity to prepare host defenses against further infection, and adjusting intestinal microbes' enzymatic activity in order to convert herbal compounds to active compounds. The SR/GF-LAB strain mixture holds potential infection-prevention agents supplied as feed additives. PMID:23533497

  1. DNA topoisomerase IIα inhibitory and anti-HIV-1 flavones from leaves and twigs of Gardenia carinata.

    PubMed

    Kongkum, Naowarat; Tuchinda, Patoomratana; Pohmakotr, Manat; Reutrakul, Vichai; Piyachaturawat, Pawinee; Jariyawat, Surawat; Suksen, Kanoknetr; Yoosook, Chalobon; Kasisit, Jitra; Napaswad, Chanita

    2012-03-01

    Four new flavones, 5,2'-dihydroxy-7,3',4',5'-tetramethoxyflavone (1), 5,2',5'-trihydroxy-7,3',4'-trimethoxyflavone (2), 5,7,2',5'-tetrahydroxy-6,3',4'-trimethoxyflavone (3) and 5,2',5'-trihydroxy-6,7,3',4'-tetramethoxyflavone (4), along with the known 5,3'-dihydroxy-6,7,4',5'-tetramethoxyflavone (5), 5,7,3',5'-tetrahydroxy-6,4'-dimethoxyflavone (6), syringaldehyde, vanillic acid and scopoletin were isolated from the leaves and twigs of Gardenia carinata (Rubiaceae). Their structures were determined by spectroscopic methods. Flavone 2 exhibited cytotoxic activity against P-388 and MCF-7 cell lines, while 3, 5 and 6 were active only in P-388 cell line. All active compounds were found to inhibit DNA topoisomerase IIα activity, which may be responsible for the observed cytotoxicity. Flavones 1-3, 5 and 6 also exhibited anti-HIV-1 activity in the anti-syncytium assay using (∆Tat/rev)MC99 virus and 1A2 cell line system; 2 was most potent. Only flavones 1 and 6 showed considerably activity against HIV-1 reverse transcriptase.

  2. Search for astrophysical rotating Ellis wormholes with x-ray reflection spectroscopy

    NASA Astrophysics Data System (ADS)

    Zhou, Menglei; Cardenas-Avendano, Alejandro; Bambi, Cosimo; Kleihaus, Burkhard; Kunz, Jutta

    2016-07-01

    Recently, two of us have found numerically rotating Ellis wormholes as solutions of four-dimensional Einstein gravity coupled to a phantom field. In this paper, we investigate possible observational signatures to identify similar objects in the Universe. These symmetric wormholes have a mass and are compact, so they may look like black holes. We study the iron line profile in the x-ray reflection spectrum of a thin accretion disk around rotating Ellis wormholes and we find some specific observational signatures that can be used to distinguish these objects from Kerr black holes. We simulate some observations with XIS/Suzaku assuming typical parameters for a bright active galactic nucleus and we conclude that current x-ray missions cannot apply strong constraints.

  3. Pressure Distribution in a Squeeze Film Spherical Bearing with Rough Surfaces Lubricated by an Ellis Fluid

    NASA Astrophysics Data System (ADS)

    Jurczak, P.; Falicki, J.

    2016-08-01

    In this paper, the solution to a problem of pressure distribution in a curvilinear squeeze film spherical bearing is considered. The equations of motion of an Ellis pseudo-plastic fluid are presented. Using Christensen's stochastic model of rough surfaces, different forms of Reynolds equation for various types of surface roughness pattern are obtained. The analytical solutions of these equations for the cases of externally pressurized bearing and squeeze film bearing are presented. Analytical solutions for the film pressure are found for the longitudinal and circumferential roughness patterns. As a result the formulae expressing pressure distribution in the clearance of bearing lubricated by an Ellis fluid was obtained. The numerical considerations for a spherical bearing are given in detail.

  4. Novel and recurrent EVC and EVC2 mutations in Ellis-van Creveld syndrome and Weyers acrofacial dyostosis.

    PubMed

    D'Asdia, Maria Cecilia; Torrente, Isabella; Consoli, Federica; Ferese, Rosangela; Magliozzi, Monia; Bernardini, Laura; Guida, Valentina; Digilio, Maria Cristina; Marino, Bruno; Dallapiccola, Bruno; De Luca, Alessandro

    2013-02-01

    Ellis van Creveld syndrome and Weyers acrofacial dysostosis are allelic disorders caused by mutations in EVC or EVC2 genes. We illustrate the results of direct analysis of whole EVC and EVC2 genes' coding regions in 32 unrelated families with clinical diagnosis of Ellis van Creveld syndrome and in 2 families with Weyers acrofacial dysostosis. We identified mutations in 27/32 (84%) cases with Ellis van Creveld syndrome and 2/2 cases with Weyers acrofacial dysostosis. Of the Ellis van Creveld syndrome cases, 20/27 (74%) had a mutation in EVC and 7/27 (26%) in EVC2 genes. The two subjects with Weyers acrofacial dysostosis had a heterozygous mutation in the last exon of EVC2. In total, we detected 25 independent EVC and 11 independent EVC2 mutations. Nineteen EVC mutations (19/25, 76%) and 4 EVC2 mutations (4/11, 36%) were novel. Also one EVC2 gene mutation found in Weyers acrofacial dysostosis was novel. In 5 unrelated cases with a clinical diagnosis of Ellis van Creveld syndrome, we did not find any mutation in either EVC or EVC2 genes. Current findings expand the Ellis van Creveld syndrome and Weyers acrofacial dysostosis mutation spectra, and provide further evidence that the last exon of EVC2 gene is a hot spot for Weyers acrofacial dysostosis mutations. Accordingly, EVC2 exon 22 should be analyzed with priority by mutation screening in individuals with a suspected diagnosis of Weyers acrofacial dysostosis.

  5. [From gene to disease; EVC, EVC2, and Ellis-van Creveld syndrome].

    PubMed

    van Hagen, J M; Baart, J A; Gille, J J P

    2005-04-23

    Ellis-van Creveld syndrome is an autosomal recessive disorder characterised by short stature with short limbs, postaxial polydactyly and congenital cardiac defects. The syndrome can be caused by mutations in the EVC gene or the EVC2 gene. The genes are located close to each other in a head-to-head configuration on chromosome 4p16. Clinical diagnosis can be confirmed by DNA analysis, which is currently offered by two laboratories in Italy.

  6. Late survival in Ellis-van Creveld syndrome - a case report.

    PubMed

    Mishra, Trinath; Routray, Satya N; Das, Biswajit

    2012-01-01

    Ellis-van Creveld syndrome (EVC) is an autosomal recessive disorder characterized by chondrodystrophy, polydactyly, ectodermal dysplasia, and cardiac anomalies. Acromelic shortening of upper and lower limbs, genu valgum, multiple frenula, deformed teeth, short ribs and narrow thorax and congenital heart diseases complete the picture. The patients with the syndrome rarely survive into adulthood. Here, we report a lady with EVC presenting for the first time in middle age.

  7. Taking prisoners: Havelock Ellis, Sigmund Freud, and the construction of homosexuality, 1897-1951.

    PubMed

    Crozier, I D

    2000-12-01

    This paper addresses the efforts of both Havelock Ellis and Sigmund Freud to posit a theory of homosexuality, and especially considers their efforts to (re-)negotiate each other's theories. Its central premise derives from the sociology of scientific knowledge: that it is not what is written, but the way that what is written is treated by ensuing experts, that makes knowledge. In the case study used in this paper, Ellis and Freud struggle to posit what they consider to be the proper model for understanding homosexual desire. They utilize aspects of each other's word, but are careful not to appear to be following each other too closely. Such a struggle to establish different schools of thought is exemplified by the informal negotiations engaged in when a student, Joseph Wortis, made contact with both Freud and Ellis. Again following sociology of scientific knowledge precepts, these informal negotiations (contained in published and archival letters) are used to show how knowledge claims are constructed, deconstructed any reconstructed by the actors who have stakes in the outcome of what is to be regarded as knowledge in the relevant communities.

  8. [Effect of extracted ZG from gardenia on Hep-2 cell membrane post infected with parainfluenza virus type 1 (PIV-1)].

    PubMed

    Guo, Shan-Shan; Huang, Yang; Zhao, Ye; Gao, Ying-Jie; Gong, Wen-Feng; Cui, Xiao-Lan

    2007-09-01

    In order to study the anti-viral mechanism of extracted ZG from Gardenia, the effect of extracted ZG on Hep-2 cell membrane potential, Na -K+-ATPase activity and membrane fluidity post infected with parainfluenza virus type 1 (PIV-1) was observed. Acetylcholine which was fluorescent labeled with DiBAC4 (3) was taken as positive control to observe the changes of membrane potential and was measured by flow cytometer. The phosphorus determination method and spectrophotometer were used to measure the Na+-K+-ATPase activity of Hep-2 cell membrane post PIV-1 infection. Hep-2 cell membrane phospholipids was labeled with fluorescent NBD-C6-HPC and membrane fluidity was measured by confocal laser scanning microscope. The results demonstated that after PIV-1 infection the Hep-2 cell membrane potential decreased significantly and the membrane was in the state of hyperpolarization, Na+-K+-ATPase activity increased and membrane fluidity decreased significantly. There was no apparent interferring effect of extracted ZG on the changes of membrane potential and Na+-K+-ATPase activity post PIV-1 infection, while membrane fluidity was improved significantly. Acetylcholine improved the state of hyperpolarization. The changes of membrane potential, Na -K+-ATPase activity and membrane fluidity might be the biomechanism of PIV-1 infectoin. The extracted ZG improved membrane fluidity to prevent from PIV-1 infection by protecting the cell membrane, which was probably the mechanism of anti-PIV-1 activity of the extracted ZG, but ZG probably had nothing to do with membrane potential and Na+-K+-ATPase activity.

  9. Strong deflection limit analysis and gravitational lensing of an Ellis wormhole

    NASA Astrophysics Data System (ADS)

    Tsukamoto, Naoki

    2016-12-01

    Observations of gravitational lenses in strong gravitational fields give us a clue to understanding dark compact objects. In this paper, we extend a method to obtain a deflection angle in a strong deflection limit provided by Bozza [Phys. Rev. D 66, 103001 (2002)] to apply to ultrastatic spacetimes. We also discuss on the order of an error term in the deflection angle. Using the improved method, we consider gravitational lensing by an Ellis wormhole, which is an ultrastatic wormhole of the Morris-Thorne class.

  10. Venus Flytrap (Dionaea muscipula Solander ex Ellis) Contains Powerful Compounds that Prevent and Cure Cancer.

    PubMed

    Gaascht, François; Dicato, Mario; Diederich, Marc

    2013-01-01

    Chemoprevention uses natural or synthetic molecules without toxic effects to prevent and/or block emergence and development of diseases including cancer. Many of these natural molecules modulate mitogenic signals involved in cell survival, apoptosis, cell cycle regulation, angiogenesis, or on processes involved in the development of metastases occur naturally, especially in fruits and vegetables bur also in non-comestible plants. Carnivorous plants including the Venus flytrap (Dionaea muscipula Solander ex Ellis) are much less investigated, but appear to contain a wealth of potent bioactive secondary metabolites. Aim of this review is to give insight into molecular mechanisms triggered by compounds isolated from these interesting plants with either therapeutic or chemopreventive potential.

  11. Ellis van creveld syndrome with synpolydactyly, an antenatal diagnosis with postnatal correlation.

    PubMed

    Kundaragi, Nischal G; Taori, Kishor; Kumawat, Ritesh; Rathod, Jawahar; Sawant, Atul E

    2011-01-01

    Ellis Van Creveld syndrome (EVC), also known as chondroectodermal dysplasia, presents at birth with short limbs accompanied by postaxial polydactyly, nail dysplasia, and dental anomalies. Other manifestations of EVC include atrial septum defects and other congenital heart diseases. We report a case of the EVC syndrome with postaxial polydactyly (Synpolydactyly with seven fingers on the right side and hexadactyly on the left side) and a partial atrioventricular canal defect diagnosed antenatally. This variation of EVS has not been reported in English literature till date.

  12. Ellis-van Creveld syndrome with unusual oral and dental findings: A rare clinical entity.

    PubMed

    Shaik, Sameeulla; Raviraj, Jayam; Dirasantchu, Suresh; Venkata, Suman S

    2016-01-01

    Ellis-van Creveld (EVC) syndrome, a form of skeletal and chondroectodermal dysplasia, is an autosomal recessive disorder characterized by a tetrad of disproportionate dwarfism, postaxial polydactyly, ectodermal dysplasia, and heart defects. In the present article, we hereby present a case of a 13-year-old girl of Indian ethnicity with EVC syndrome with a remarkable number of classical oral and dental features, with unusual findings such as taurodontism and talons cusp. Such dental findings were reported in few cases only. Despite the fact that oral manifestations play an important role in the diagnosis of EVC, only a few detailed reports have been published in the dental literature.

  13. Ellis-van Creveld syndrome in adulthood: extending the clinical spectrum.

    PubMed

    Pérez-Andreu, Joaquín; Ray, Victor Glenn; Arribas, José María; Sánchez, Sergio Juan

    2015-06-01

    Ellis-van Creveld (EvC) syndrome is a rare autosomal recessive malformation disorder. Cardiac defects are observed in about 50% of EvC cases. Surgical data is lacking on the prognosis and life expectancy of EvC patients. Herein, we report the case of a 38-year-old man with EvC syndrome who underwent two surgical corrections for cardiac anomalies. This report supplements the available information on the clinical course of EvC syndrome in older patients.

  14. [Eugenics and immigration selection: notes on the debate between Alfredo Ellis Junior, Oliveira Vianna, and Menotti Del Picchia, 1926].

    PubMed

    El-Dine, Lorenna Ribeiro Zem

    2016-12-01

    This text analyzes the bill submitted by Alfredo Ellis Junior to the São Paulo legislature in August 1926, which would allow studies to be made of immigrants in São Paulo in order to orient immigration selection policies. It highlights the opinions of Menotti Del Picchia and Oliveira Vianna about the research agenda put forward by Alfredo Ellis Junior, focusing on the different conceptions about the race issue and immigration held in the 1920s. We suggest that Menotti Del Picchia's divergence from Alfredo Ellis Junior and Oliveira Vianna could be interpreted as a dispute between literati and scientists over the legitimacy of their respective knowledge about the Brazilian reality and the proposal of policies for the country.

  15. ELLI-1, a novel germline protein, modulates RNAi activity and P-granule accumulation in Caenorhabditis elegans

    PubMed Central

    Andralojc, Karolina M.; Kelly, Ashley L.; Tanner, Paige C.

    2017-01-01

    Germ cells contain non-membrane bound cytoplasmic organelles that help maintain germline integrity. In C. elegans they are called P granules; without them, the germline undergoes partial masculinization and aberrant differentiation. One key P-granule component is the Argonaute CSR-1, a small-RNA binding protein that antagonizes accumulation of sperm-specific transcripts in developing oocytes and fine-tunes expression of proteins critical to early embryogenesis. Loss of CSR-1 complex components results in a very specific, enlarged P-granule phenotype. In a forward screen to identify mutants with abnormal P granules, ten alleles were recovered with a csr-1 P-granule phenotype, eight of which contain mutations in known components of the CSR-1 complex (csr-1, ego-1, ekl-1, and drh-3). The remaining two alleles are in a novel gene now called elli-1 (enlarged germline granules). ELLI-1 is first expressed in primordial germ cells during mid-embryogenesis, and continues to be expressed in the adult germline. While ELLI-1 forms cytoplasmic aggregates, they occasionally dock, but do not co-localize with P granules. Instead, the majority of ELLI-1 aggregates accumulate in the shared germline cytoplasm. In elli-1 mutants, several genes that promote RNAi and P-granule accumulation are upregulated, and embryonic lethality, sterility, and RNAi resistance in a hypomorphic drh-3 allele is enhanced, suggesting that ELLI-1 functions with CSR-1 to modulate RNAi activity, P-granule accumulation, and post-transcriptional expression in the germline. PMID:28182654

  16. Insight of Saffron Proteome by Gel-Electrophoresis.

    PubMed

    Paredi, Gianluca; Raboni, Samanta; Marchesani, Francesco; Ordoudi, Stella A; Tsimidou, Maria Z; Mozzarelli, Andrea

    2016-01-29

    Saffron is a spice comprised of the dried stigmas and styles of Crocus sativus L. flowers and, since it is very expensive, it is frequently adulterated. So far, proteomic tools have never been applied to characterize the proteome of saffron or identify possible cases of fraud. In this study, 1D-Gel Electrophoresis was carried out to characterize the protein profile of (i) fresh stigmas and styles of the plant; (ii) dried stigmas and styles from different geographical origins (Spanish, Italian, Greek and Iranian) that had been stored for various periods of time after their processing; and (iii) two common plant adulterants, dried petals of Carthamus tinctorius L. and dried fruits of Gardenia jasminoides Ellis. A selective protein extraction protocol was applied to avoid interference from colored saffron metabolites, such as crocins, during electrophoretic analyses of saffron. We succeeded in separating and assigning the molecular weights to more than 20 proteins. In spite of the unavailability of the genome of saffron, we were able to identify five proteins by Peptide Mass Fingerprinting: phosphoenolpyruvate carboxylase 3, heat shock cognate 70 KDa protein, crocetin glucosyltransferase 2, α-1,4-glucan-protein synthase and glyceraldehydes-3-phosphate dehydrogenase-2. Our findings indicate that (i) few bands are present in all saffron samples independently of origin and storage time, with amounts that significantly vary among samples and (ii) aging during saffron storage is associated with a reduction in the number of detectable bands, suggesting that proteases are still active. The protein pattern of saffron was quite distinct from those of two common adulterants, such as the dried petals of Carthamus tinctorius and the dried fruits of Gardenia jasminoides indicating that proteomic analyses could be exploited for detecting possible frauds.

  17. Determination of gardenia yellow colorants in soft drink, pastry, instant noodles with ultrasound-assisted extraction by high performance liquid chromatography-electrospray ionization tandem mass spectrum.

    PubMed

    Zhou, Wei-E; Zhang, Yuan; Li, Yang; Ling, Yun; Li, Hong-Na; Li, Shao-Hui; Jiang, Shou-Jun; Ren, Zhi-Qin; Huang, Zhi-Qiang; Zhang, Feng

    2016-05-13

    A novel, rapid and simple analytical method was developed for the quantitative determination of crocin, crocetin and geniposide in soft drink, pastry and instant noodles. The solid samples were relatively homogenized into powders and fragments. The gardenia yellow colorants were successively extracted with methanol using ultrasound-assisted extraction. The analytes were quantitatively measured in the extracts by liquid chromatography coupled with electrospray ionization tandem mass spectrometry. High correlation coefficients (r(2)>0.995) of crocin, crocetin and geniposide were obtained within their linear ranges respectively (50-1000ng/mL, 50-1000ng/mL, 15-240ng/mL) by external standard method. The limits of detection (LODs) were 0.02μg/g for crocin, 0.01μg/g for crocetin and 0.002μg/g for geniposide. And the limits of quantitation (LOQs) were in the ranges of 0.05-0.45μg/g for crocin, and in the ranges of 0.042-0.32μg/g for crocetin, and in the ranges of 0.02-0.15μg/g for geniposide in soft drink, pastry and instant noodles samples. The average recoveries of crocin, crocetin and geniposide ranged from 81.3% to 117.6% in soft drink, pastry and instant noodles. The intra- and inter-day precisions were respectively in the range of 1.3-4.8% and 1.7-11.8% in soft drink, pastry and instant noodle. The developed methods were successfully validated and applied to the soft drink, pastry, and instant noodles collected from the located market in Beijing from China. Crocin, crocetin and geniposide were detected in the collected samples. The average concentrations ranged from 0.84 to 4.20mg/g for crocin, and from 0.62 to 3.11mg/g for crocetin, and from 0.18 to 0.79mg/g for gardenia in various food samples. The method can provide evidences for government to determine gardenia yellow pigments and geniposide in food.

  18. Expression of the Ellis-van Creveld (Evc) gene in the rat tibial growth plate.

    PubMed

    Tsuji, Takehito; Nakamura, Hiroaki; Hirata, Azumi; Yamamoto, Toshio

    2004-08-01

    Ellis-van Creveld (EvC) syndrome is an autosomal recessive chondrodysplasia characterized by short limbs, postaxial polydactyly, natal teeth, and dysplastic nails. The Ellis-van Creveld (EVC) gene, which is mutated in patients with EvC syndrome, has been identified by positional cloning. However, the physiological roles of the EVC gene have not been elucidated. Histopathological analyses of EvC syndrome have shown disturbed chondrocytic phenotypes during cartilage development. We therefore postulated that the EVC gene is a critical factor for chondrocytes during endochondral ossification. The present study focuses on the relationship between the Evc gene and chondrocytes, and examines Evc gene expression in the rat tibial growth plate at the mRNA and protein levels. Evc mRNA in tibial epiphyseal cartilage was expressed at postnatal day (P) 1, P28, and P56 by RT-PCR. Immunohistochemical analyses localized the Evc protein mainly in prehypertrophic and hypertrophic chondrocytes of the epiphyseal growth plate in the tibia during the embryonic and postnatal periods. Evc mRNA was also detected in prehypertrophic and hypertrophic chondrocytes by in situ hybridization. These results indicate that the Evc gene functions mainly in the prehypertrophic and hypertrophic chondrocytes of the epiphyseal growth plate. The data presented here are important for future studies of the underlying mechanism of chondrodysplasia in EvC syndrome.

  19. 75 FR 61706 - Reorganization of Foreign-Trade Zone 113 Under Alternative Site Framework; Ellis County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-06

    ... Foreign-Trade Zones Board Reorganization of Foreign-Trade Zone 113 Under Alternative Site Framework; Ellis... Board adopted the alternative site framework (ASF) in December 2008 (74 FR 1170, 01/12/09; correction 74... alternative site framework is approved, subject to the FTZ Act and the Board's regulations, including...

  20. Psychological Chauvinism and Nuclear Holocaust: A Response to Albert Ellis and Defense of Non-Rational Emotive Therapies.

    ERIC Educational Resources Information Center

    Walsh, Roger

    1989-01-01

    Claims Ellis' 1986 article on psychology and nuclear holocaust did not address certain key issues and made inaccurate criticisms of non-rational emotive therapies. Attempts to correct these errors and to emphasize the importance of open-minded cooperation among psychologists of differing theoretical persuasions. (Author)

  1. Ellis Englesberg and the discovery of positive control in gene regulation.

    PubMed

    Hahn, Steven

    2014-10-01

    Based on his work with the Escherichia coli l-arabinose operon, Ellis Englesberg proposed in 1965 that the regulatory gene araC was an "activator gene" required for positive control of the ara operon. This challenged the widely held belief in a universal mechanism of negative regulation proposed earlier by Jacob and Monod. For years, Englesberg's model was met with deep skepticism. Despite much frustration with complex ad hoc explanations used to challenge his model, Englesberg persisted until the evidence for positive control in ara and other systems became overwhelming. Englesberg's pioneering work enriched the original operon model and had a lasting impact in opening new and exciting ways of thinking about transcriptional regulation.

  2. Venus Flytrap (Dionaea muscipula Solander ex Ellis) Contains Powerful Compounds that Prevent and Cure Cancer

    PubMed Central

    Gaascht, François; Dicato, Mario; Diederich, Marc

    2013-01-01

    Chemoprevention uses natural or synthetic molecules without toxic effects to prevent and/or block emergence and development of diseases including cancer. Many of these natural molecules modulate mitogenic signals involved in cell survival, apoptosis, cell cycle regulation, angiogenesis, or on processes involved in the development of metastases occur naturally, especially in fruits and vegetables bur also in non-comestible plants. Carnivorous plants including the Venus flytrap (Dionaea muscipula Solander ex Ellis) are much less investigated, but appear to contain a wealth of potent bioactive secondary metabolites. Aim of this review is to give insight into molecular mechanisms triggered by compounds isolated from these interesting plants with either therapeutic or chemopreventive potential. PMID:23971004

  3. The gene for the Ellis-van Creveld syndrome is located on chromosome 4p16

    SciTech Connect

    Polymeropoulos, M.H.; Ide, S.E.; Wright, M.

    1996-07-01

    Ellis-van Creveld syndrome (EVC) is an autosomal recessive disorder characterized by disproportionate dwarfism, polydactyly, and congenital heart disease. This rare disorder is found with increased frequency among the Old Order Amish community in Lancaster County, Pennsylvania. We have used linkage analysis to localize the gene responsible for the EVC phenotype in nine interrelated Amish pedigrees and three unrelated families from Mexico, Ecuador, and Brazil. We now report the linkage for the Ellisvan Creveld syndrome gene to markers on the distal short arm of human chromosome 4, with Z{sub max} = 6.91 at {theta} = 0.02 for marker HOX7, in a region proximal to the FGFR3 gene responsible for the achondroplasia phenotype. 17 refs., 2 figs., 1 tab.

  4. Active movements in plants: Mechanism of trap closure by Dionaea muscipula Ellis.

    PubMed

    Markin, Vladislav S; Volkov, Alexander G; Jovanov, Emil

    2008-10-01

    The Venus flytrap (Dionaea muscipula Ellis) captures insects with one of the most rapid movements in the plant kingdom. We investigated trap closure by mechanical and electrical stimuli using the novel charge-injection method and high-speed recording. We proposed a new hydroelastic curvature mechanism, which is based on the assumption that the lobes possess curvature elasticity and are composed of outer and inner hydraulic layers with different hydrostatic pressure. The open state of the trap contains high elastic energy accumulated due to the hydrostatic pressure difference between the hydraulic layers of the lobe. Stimuli open pores connecting the two layers, water rushes from one hydraulic layer to another, and the trap relaxes to the equilibrium configuration corresponding to the closed state. In this paper we derived equations describing this system based on elasticity Hamiltonian and found closing kinetics. The novel charge-injection stimulation method gives insight into mechanisms of the different steps of signal transduction and response in the plant kingdom.

  5. Morphing structures of the Dionaea muscipula Ellis during the trap opening and closing.

    PubMed

    Volkov, Alexander G; Forde-Tuckett, Victoria; Volkova, Maya I; Markin, Vladislav S

    2014-01-01

    The Venus flytrap is a marvelous plant that has intrigued scientists since the times of Charles Darwin. This carnivorous plant is capable of very fast movements to catch a prey. We found that the maximal speed of the trap closing in the Dionaea muscipula Ellis is about 130,000 times faster than the maximal speed of the trap opening. The mechanism and kinetics of this movement was debated for a long time. Here, the most recent Hydroelastic Curvature Model is applied to the analysis of this movement during closing and opening of the trap with or without a prey. Equations describing the trap movement were derived and verified with experimental data. Chloroform and ether, both anesthetic agents, induce action potentials and close the trap without the mechanical stimulation of trigger hairs. We tested this by dropping 10 μL of ether on the midrib inside the trap without touching any of the mechanosensitive trigger hairs. The trap closed slowly in 10 s. This is at least 20 times slower than the closing of the trap mechanically or electrically. The similar effect can be induced by placing 10 μL of chloroform on the midrib inside the trap, however, the lobes closing time in this case is as fast as closing after mechanical stimulation of the trigger hairs.

  6. Morphing structures of the Dionaea muscipula Ellis during the trap opening and closing

    PubMed Central

    Volkov, Alexander G; Forde-Tuckett, Victoria; Volkova, Maya I; Markin, Vladislav S

    2014-01-01

    The Venus flytrap is a marvelous plant that has intrigued scientists since the times of Charles Darwin. This carnivorous plant is capable of very fast movements to catch a prey. We found that the maximal speed of the trap closing in the Dionaea muscipula Ellis is about 130 000 times faster than the maximal speed of the trap opening. The mechanism and kinetics of this movement was debated for a long time. Here, the most recent Hydroelastic Curvature Model is applied to the analysis of this movement during closing and opening of the trap with or without a prey. Equations describing the trap movement were derived and verified with experimental data. Chloroform and ether, both anesthetic agents, induce action potentials and close the trap without the mechanical stimulation of trigger hairs. We tested this by dropping 10 μL of ether on the midrib inside the trap without touching any of the mechanosensitive trigger hairs. The trap closed slowly in 10 s. This is at least 20 times slower than the closing of the trap mechanically or electrically. The similar effect can be induced by placing 10 μL of chloroform on the midrib inside the trap, however, the lobes closing time in this case is as fast as closing after mechanical stimulation of the trigger hairs. PMID:24618927

  7. Mutations in a new gene in Ellis-van Creveld syndrome and Weyers acrodental dysostosis.

    PubMed

    Ruiz-Perez, V L; Ide, S E; Strom, T M; Lorenz, B; Wilson, D; Woods, K; King, L; Francomano, C; Freisinger, P; Spranger, S; Marino, B; Dallapiccola, B; Wright, M; Meitinger, T; Polymeropoulos, M H; Goodship, J

    2000-03-01

    Ellis-van Creveld syndrome (EvC, MIM 225500) is an autosomal recessive skeletal dysplasia characterized by short limbs, short ribs, postaxial polydactyly and dysplastic nails and teeth. Congenital cardiac defects, most commonly a defect of primary atrial septation producing a common atrium, occur in 60% of affected individuals. The disease was mapped to chromosome 4p16 in nine Amish subpedigrees and single pedigrees from Mexico, Ecuador and Brazil. Weyers acrodental dysostosis (MIM 193530), an autosomal dominant disorder with a similar but milder phenotype, has been mapped in a single pedigree to an area including the EvC critical region. We have identified a new gene (EVC), encoding a 992-amino-acid protein, that is mutated in individuals with EvC. We identified a splice-donor change in an Amish pedigree and six truncating mutations and a single amino acid deletion in seven pedigrees. The heterozygous carriers of these mutations did not manifest features of EvC. We found two heterozygous missense mutations associated with a phenotype, one in a man with Weyers acrodental dysostosis and another in a father and his daughter, who both have the heart defect characteristic of EvC and polydactyly, but not short stature. We suggest that EvC and Weyers acrodental dysostosis are allelic conditions.

  8. Ellis-van Creveld syndrome associated with chronic intestinal pseudo-obstruction.

    PubMed

    Iwakura, Hideo; Fujii, Katsunori; Furutani, Yoshiyuki; Takatani, Tomozumi; Ebata, Ryota; Nakanishi, Toshio; Mitsunaga, Tetsuya; Saito, Takeshi; Kishimoto, Takashi; Yoshida, Hideo; Shimojo, Naoki

    2016-01-01

    Ellis-van Creveld (EVC) syndrome is a rare autosomal recessive disorder characterized by hypoplastic nails, polydactyly, and achondroplasia. Patients usually exhibit normal cognitive function and no remarkable developmental delay. We herein present an unusual case of EVC syndrome. A Japanese 2-year-old boy was born at term, but immediately developed severe respiratory failure due to thorax deformity, postaxial polydactyly and nail hypoplasia. We identified a novel pattern of germinal compound heterozygous nonsense EVC2 mutations of c.1814C > A (p. S605X) and c.2653C > T (p. R885X), leading to the diagnosis of EVC syndrome. Interestingly, he also had severe developmental delay, and suddenly developed excessive abdominal distension at the age of 2. On surgery, extensive necrotic bowel with chronic intestinal pseudo-obstruction was noted. This is, to our knowledge, a most severe phenotype of EVC syndrome, illustrating that the specific pattern of EVC2 compound heterozygous mutations may cause severe developmental delay and intestinal malfunction.

  9. Two Adult Patients with Ellis-van Creveld Syndrome Extending the Clinical Spectrum.

    PubMed

    Rudnik-Schöneborn, S; Zerres, K; Graul-Neumann, L; Wiegand, S; Mellerowicz, H; Hehr, U

    2011-09-01

    Ellis-van Creveld (EvC) syndrome is a rare autosomal recessive malformation syndrome with the main features cardiac defects, postaxial hexadactyly, mesomelic shortening of the limbs, short ribs, dysplastic nails and teeth, oral frenula and various other abnormalities while mental function is normal. We describe 2 adult EvC patients with the cardinal skeletal features of mesomelic short stature and severe, progressive genu valgum deformity, resulting from loss of function mutations in the EVC genes. While the genu valgum was the predominating and disabling feature in patient 1, patient 2 showed acroosteolyses in the distal phalanges and a symmetrical synostosis of metacarpals in his hands. Moreover, patient 2 developed synostoses in the additional fingers in adolescence which had not been present at the age of 12 years, suggesting a further progression of skeletal disease. Joint fusion of phalanges so far has not been reported in EvC syndrome. Our data further expand the phenotypic spectrum of EvC related skeletal malformations and contribute important new information on the clinical course of EvC syndrome with increasing age.

  10. Analysis of Ellis van Creveld syndrome gene products: implications for cardiovascular development and disease.

    PubMed

    Sund, Kristen Lipscomb; Roelker, Stephanie; Ramachandran, Vijaya; Durbin, Lisa; Benson, D Woodrow

    2009-05-15

    Mutations identified in a cohort of patients with atrioventricular septal defects as a part of Ellis van Creveld syndrome (EvC syndrome) led us to study the role of two non-homologous genes, EVC and LBN, in heart development and disease pathogenesis. To address the cause of locus heterogeneity resulting in an indistinguishable heart-hand phenotype, we carried out in situ hybridization and immunofluorescence and identified co-localization of Evc and Lbn mRNA and protein. In the heart, expression was identified to be strongest in the secondary heart field, including both the outflow tract and the dorsal mesenchymal protrusion, but was also found in mesenchymal structures of the atrial septum and the atrioventricular cushions. Finally, we studied the transcriptional hierarchy of EVC and LBN but did not find any evidence of direct transcriptional interregulation between the two. Due to the locus heterogeneity of human mutations predicted to result in a loss of protein function, a bidirectional genomic organization and overlapping expression patterns, we speculate that these proteins function coordinately in cardiac development and that loss of this coordinate function results in the characteristics of EvC syndrome.

  11. Growth hormone analysis and treatment in Ellis-van Creveld syndrome.

    PubMed

    Versteegh, Florens G A; Buma, Sannine A; Costin, Gertrude; de Jong, Wilfried C; Hennekam, Raoul C M

    2007-09-15

    Little is known on growth, growth hormone (GH) levels and GH treatment in patients with Ellis-van Creveld syndrome (EvC). The aim of the present study was to assess growth, growth hormone status and the possible effectiveness of GH treatment in literature and in a small series of EvC patients. A review of literature indicated retarded growth for most EvC patients (-2 to -4.5 SDS) and minimal data on GH levels or treatment which did not allow any conclusion. We studied eight EvC patients, seven of whom were treated with GH. Four were GH deficient (GHD) and four were GH sufficient. In all patients treated with GH, first year growth velocity increased. In three of the four GHD and in one GH-sufficient patient a gain in height SDS was noted. In the present small EvC series GHD occurred more often than expected. Patient acquisition through the Growth Hormone Database will have caused a significant bias, but the present results indicate that GH treatment may improve growth in at least some patients with EvC. Therefore we conclude that EvC patients may benefit from being tested for GHD and, if indicated, treated. In addition a prospective study to evaluate GH status and linear growth in patients with EvC as well as the potential effectiveness of GH treatment is warranted.

  12. Analysis of Ellis van Creveld syndrome gene products: implications for cardiovascular development and disease

    PubMed Central

    Sund, Kristen Lipscomb; Roelker, Stephanie; Ramachandran, Vijaya; Durbin, Lisa; Benson, D. Woodrow

    2009-01-01

    Mutations identified in a cohort of patients with atrioventricular septal defects as a part of Ellis van Creveld syndrome (EvC syndrome) led us to study the role of two non-homologous genes, EVC and LBN, in heart development and disease pathogenesis. To address the cause of locus heterogeneity resulting in an indistinguishable heart–hand phenotype, we carried out in situ hybridization and immunofluorescence and identified co-localization of Evc and Lbn mRNA and protein. In the heart, expression was identified to be strongest in the secondary heart field, including both the outflow tract and the dorsal mesenchymal protrusion, but was also found in mesenchymal structures of the atrial septum and the atrioventricular cushions. Finally, we studied the transcriptional hierarchy of EVC and LBN but did not find any evidence of direct transcriptional interregulation between the two. Due to the locus heterogeneity of human mutations predicted to result in a loss of protein function, a bidirectional genomic organization and overlapping expression patterns, we speculate that these proteins function coordinately in cardiac development and that loss of this coordinate function results in the characteristics of EvC syndrome. PMID:19251731

  13. Novel mutations in EVC cause aberrant splicing in Ellis-van Creveld syndrome.

    PubMed

    Shi, Lisong; Luo, Chunyan; Ahmed, Mairaj K; Attaie, Ali B; Ye, Xiaoqian

    2016-04-01

    Ellis-van Creveld syndrome (EvC) is a rare autosomal recessive disorder characterized by disproportionate chondrodysplasia, postaxial polydactyly, nail dystrophy, dental abnormalities and in a proportion of patients, congenital cardiac malformations. Weyers acrofacial dysostosis (Weyers) is another dominantly inherited disorder allelic to EvC syndrome but with milder phenotypes. Both disorders can result from loss-of-function mutations in either EVC or EVC2 gene, and phenotypes associated with the two gene mutations are clinically indistinguishable. We present here a clinical and molecular analysis of a Chinese family manifested specific features of EvC syndrome. Sequencing of both EVC and EVC2 identified two novel heterozygous splice site mutations c.384+5G>C in intron 3 and c.1465-1G>A in intron 10 in EVC, which were inherited from mother and father, respectively. In vitro minigene expression assay, RT-PCR and sequencing analysis demonstrated that c.384+5G>C mutation abolished normal splice site and created a new cryptic acceptor site within exon 4, whereas c.1465-1G>A mutation affected consensus splice junction site and resulted in full exon 11 skipping. These two aberrant pre-mRNA splicing processes both produced in-frame abnormal transcripts that possibly led to abolishment of important functional domains. To our knowledge, this is the first report of EVC mutations that cause EvC syndrome in Chinese population. Our data revealed that EVC splice site mutations altered splicing pattern and helped elucidate the pathogenesis of EvC syndrome.

  14. Ellis-van Creveld Syndrome in Grey Alpine Cattle: Morphologic, Immunophenotypic, and Molecular Characterization.

    PubMed

    Muscatello, L V; Benazzi, C; Dittmer, K E; Thompson, K G; Murgiano, L; Drögemüller, C; Avallone, G; Gentile, A; Edwards, J F; Piffer, C; Bolcato, M; Brunetti, B

    2015-09-01

    Ellis-van Creveld (EvC) syndrome is a human autosomal recessive disorder caused by a mutation in either the EVC or EVC2 gene, and presents with short limbs, polydactyly, and ectodermal and heart defects. The aim of this study was to understand the pathologic basis by which deletions in the EVC2 gene lead to chondrodysplastic dwarfism and to describe the morphologic, immunohistochemical, and molecular hallmarks of EvC syndrome in cattle. Five Grey Alpine calves, with a known mutation in the EVC2 gene, were autopsied. Immunohistochemistry was performed on bone using antibodies to collagen II, collagen X, sonic hedgehog, fibroblast growth factor 2, and Ki67. Reverse transcription polymerase chain reaction was performed to analyze EVC1 and EVC2 gene expression. Autopsy revealed long bones that were severely reduced in length, as well as genital and heart defects. Collagen II was detected in control calves in the resting, proliferative, and hypertrophic zones and in the primary and secondary spongiosa, with a loss of labeling in the resting zone of 2 dwarfs. Collagen X was expressed in hypertrophic zone in the controls but was absent in the EvC cases. In affected calves and controls, sonic hedgehog labeled hypertrophic chondrocytes and primary and secondary spongiosa similarly. FGF2 was expressed in chondrocytes of all growth plate zones in the control calves but was lost in most EvC cases. The Ki67 index was lower in cases compared with controls. EVC and EVC2 transcripts were detected. Our data suggest that EvC syndrome of Grey Alpine cattle is a disorder of chondrocyte differentiation, with accelerated differentiation and premature hypertrophy of chondrocytes, and could be a spontaneous model for the equivalent human disease.

  15. Epigenetic deregulation of Ellis Van Creveld confers robust Hedgehog signaling in adult T-cell leukemia.

    PubMed

    Takahashi, Ryutaro; Yamagishi, Makoto; Nakano, Kazumi; Yamochi, Toshiko; Yamochi, Tadanori; Fujikawa, Dai; Nakashima, Makoto; Tanaka, Yuetsu; Uchimaru, Kaoru; Utsunomiya, Atae; Watanabe, Toshiki

    2014-09-01

    One of the hallmarks of cancer, global gene expression alteration, is closely associated with the development and malignant characteristics associated with adult T-cell leukemia (ATL) as well as other cancers. Here, we show that aberrant overexpression of the Ellis Van Creveld (EVC) family is responsible for cellular Hedgehog (HH) activation, which provides the pro-survival ability of ATL cells. Using microarray, quantitative RT-PCR and immunohistochemistry we have demonstrated that EVC is significantly upregulated in ATL and human T-cell leukemia virus type I (HTLV-1)-infected cells. Epigenetic marks, including histone H3 acetylation and Lys4 trimethylation, are specifically accumulated at the EVC locus in ATL samples. The HTLV-1 Tax participates in the coordination of EVC expression in an epigenetic fashion. The treatment of shRNA targeting EVC, as well as the transcription factors for HH signaling, diminishes the HH activation and leads to apoptotic death in ATL cell lines. We also showed that a HH signaling inhibitor, GANT61, induces strong apoptosis in the established ATL cell lines and patient-derived primary ATL cells. Therefore, our data indicate that HH activation is involved in the regulation of leukemic cell survival. The epigenetically deregulated EVC appears to play an important role for HH activation. The possible use of EVC as a specific cell marker and a novel drug target for HTLV-1-infected T-cells is implicated by these findings. The HH inhibitors are suggested as drug candidates for ATL therapy. Our findings also suggest chromatin rearrangement associated with active histone markers in ATL.

  16. Ellis Van Creveld2 is Required for Postnatal Craniofacial Bone Development.

    PubMed

    Badri, Mohammed K; Zhang, Honghao; Ohyama, Yoshio; Venkitapathi, Sundharamani; Kamiya, Nobuhiro; Takeda, Haruko; Ray, Manas; Scott, Greg; Tsuji, Takehito; Kunieda, Tetsuo; Mishina, Yuji; Mochida, Yoshiyuki

    2016-08-01

    Ellis-van Creveld (EvC) syndrome is a genetic disorder with mutations in either EVC or EVC2 gene. Previous case studies reported that EvC patients underwent orthodontic treatment, suggesting the presence of craniofacial bone phenotypes. To investigate whether a mutation in EVC2 gene causes a craniofacial bone phenotype, Evc2 knockout (KO) mice were generated and cephalometric analysis was performed. The heads of wild type (WT), heterozygous (Het) and homozygous Evc2 KO mice (1-, 3-, and 6-week-old) were prepared and cephalometric analysis based on the selected reference points on lateral X-ray radiographs was performed. The linear and angular bone measurements were then calculated, compared between WT, Het and KO and statistically analyzed at each time point. Our data showed that length of craniofacial bones in KO was significantly lowered by ∼20% to that of WT and Het, the growth of certain bones, including nasal bone, palatal length, and premaxilla was more affected in KO, and the reduction in these bone length was more significantly enhanced at later postnatal time points (3 and 6 weeks) than early time point (1 week). Furthermore, bone-to-bone relationship to cranial base and cranial vault in KO was remarkably changed, i.e. cranial vault and nasal bone were depressed and premaxilla and mandible were developed in a more ventral direction. Our study was the first to show the cause-effect relationship between Evc2 deficiency and craniofacial defects in EvC syndrome, demonstrating that Evc2 is required for craniofacial bone development and its deficiency leads to specific facial bone growth defect. Anat Rec, 299:1110-1120, 2016. © 2016 Wiley Periodicals, Inc.

  17. Ellis-van Creveld syndrome and congenital heart defects: presentation of an additional 32 cases.

    PubMed

    Hills, Christine B; Kochilas, Lazaros; Schimmenti, Lisa A; Moller, James H

    2011-10-01

    Ellis-van Creveld (EVC) syndrome is a rare genetic abnormality that has been linked to a mutation in the EVC or EVC2 genes. Common atrium (CA) is an uncommon cardiac malformation, and yet it is commonly found in patients with EVC. We performed a retrospective review of the cases submitted to the Pediatric Cardiac Care Consortium (PCCC) between 1982 and 2007. A review of the English-language literature for previously published cases, as well as current genetic research findings, was also performed. Thirty-two pediatric patients with congenital heart disease (CHD) and EVC syndrome were identified in the PCCC database. Twenty-eight (88%) had an endocardial cushion defect, with 15 of these having primary failure of atrial septation resulting in CA. Persistent left superior vena cava (LSVC) and pulmonary venous connection abnormalities were common. The incidence of persistent LSVC and pulmonary venous abnormalities were greater than previously reported for patients with EVC. Our study reviews the reported literature and adds 32 additional cases from the PCCC database. Review of the cardiac phenotype in patients with EVC syndrome reveals a characteristic pattern of atrioventricular canal defects with systemic and pulmonary venous abnormalities. The frequent association of these abnormalities is strongly reminiscent of the cardiac phenotype found in patients with heterotaxy syndromes. Emerging molecular and developmental studies suggest that EVC and EVC2 proteins may be important for cilia function, which is implicated in the pathogenesis of heterotaxy syndromes. It is speculated that coordinate function between the EVC proteins is required for a cilia-dependent cardiac morphogenesis.

  18. Molecular and clinical analysis of Ellis-van Creveld syndrome in the United Arab Emirates

    PubMed Central

    2010-01-01

    Background Ellis-van Creveld (EvC) syndrome is an autosomal recessive chondrodysplastic condition with clinical manifestations that include short-limbs and ribs, postaxial polydactyly and dysplastic nails and teeth. In about two thirds of patients, mutations in either EVC or EVC2 genes have been found to be the underlying cause. Methods In this paper, we describe the molecular (DNA sequencing) and clinical analysis of six children diagnosed with EvC from four different families from the United Arab Emirates (UAE). Results All the children had the common clinical and radiological features of this syndrome. However, DNA sequence analysis of the genes shown to be involved (EVC and EVC2) revealed a novel splice site mutation (c.2047-1G>T) in intron 13 of EVC2 gene in one family. In addition, we confirm previous mutational analyses that showed a truncating mutation in exon 13 of EVC gene (c.1813C>T; p.Q605X) in the second family and a single nucleotide deletion (c.981delG; p.K327fs) in exon 8 of EVC2 gene in the third family. No mutations in the exons, splice sites or the promoter regions of either gene have been found in the index case of the fourth family who exhibited "EvC-like" features. Conclusions Given the small population size of UAE, our data illustrates further the molecular heterogeneity observed in EvC patients and excludes the possibility of a common founder effect for this condition in the UAE reflecting the current ethnic diversity of the country. PMID:20184732

  19. Autosomal dominant postaxial polydactyly, nail dystrophy, and dental abnormalities map to chromosome 4p16, in the region containing the Ellis-van Creveld syndrome locus.

    PubMed Central

    Howard, T D; Guttmacher, A E; McKinnon, W; Sharma, M; McKusick, V A; Jabs, E W

    1997-01-01

    We have studied a four-generation family with features of Weyers acrofacial dysostosis, in which the proband has a more severe phenotype, resembling Ellis-van Creveld syndrome. Weyers acrofacial dysostosis is an autosomal dominant condition with dental anomalies, nail dystrophy, postaxial polydactyly, and mild short stature. Ellis-van Creveld syndrome is a similar condition, with autosomal recessive inheritance and the additional features of disproportionate dwarfism, thoracic dysplasia, and congenital heart disease. Linkage and haplotype analysis determined that the disease locus in this pedigree resides on chromosome 4p16, distal to the genetic marker D4S3007 and within a 17-cM region flanking the genetic locus D4S2366. This region includes the Ellis-van Creveld syndrome locus, which previously was reported to map within a 3-cM region between genetic markers D4S2957 and D4S827. Either the genes for the condition in our family and for Ellis-van Creveld syndrome are near one another or these two conditions are allelic with mutations in the same gene. These data also raise the possibility that Weyers acrofacial dysostosis is the heterozygous expression of a mutation that, in homozygous form, causes the autosomal recessive disorder Ellis-van Creveld syndrome. Images Figure 1 PMID:9399901

  20. The history of early low frequency radio astronomy in Australia. 3: Ellis, Reber and the Cambridge field station near Hobart

    NASA Astrophysics Data System (ADS)

    George, Martin; Orchiston, Wayne; Slee, Bruce; Wielebinski, Richard

    2015-07-01

    Low frequency radio astronomy in Tasmania began with the arrival of Grote Reber to the State in 1954. After analysing ionospheric data from around the world, he concluded that Tasmania would be a very suitable place to carry out low frequency observations. Communications with Graeme Ellis in Tasmania, who had spent several years studying the ionosphere, led to a collaboration between the two in 1955 during which year they made observations at Cambridge, near Hobart. Their observations took place at four frequencies between 2.13 MHz and 0.52 MHz inclusive, with the results at the higher frequencies revealing a clear celestial component

  1. Biomimetic robotic Venus flytrap (Dionaea muscipula Ellis) made with ionic polymer metal composites.

    PubMed

    Shahinpoor, Mohsen

    2011-12-01

    The work described in this paper is a novel design of a robotic Venus flytrap (VFT) (Dionaea muscipula Ellis) by means of ionic polymeric metal composite (IPMC) artificial muscles as distributed nanosensors and nanoactuators. Rapid muscular movements in carnivorous plants, such as VFT, which are triggered by antenna-like sensors (trigger hair), present a golden key to study distributed biomolecular motors. Carnivorous plants, such as VFT, possess built-in intelligence (trigger hairs), as a strategy to capture prey, that can be turned on in a controlled manner. In the case of the VFT, the prey that is lured by the sweet nectar in the VFT pair of jaw-like lobes has to flip and move the trigger hairs, which are colorless, bristle-like and pointed. The dynamically moved trigger hairs then electro-elastically send an electric signal to the internal ions in the lobe to migrate outwardly for the jaw-like lobes to close rapidly to capture the prey. The manner in which the VFT lobes bend inward to capture the prey shows a remarkable similarity with typical IPMCs bending in an electric field. Furthermore, the mechano-electrical sensing characteristics of IPMCs also show a remarkable resemblance to mechano-electrical trigger hairs on the lobes of the VFT. The reader is referred to a number of papers in connection with sensing and actuation of IPMCs in particular. Thus, one can integrate IPMC lobes with a common electrode in the middle of one end of the lobes to act like a spine and use IPMC bristles as trigger finger to sense the intrusion of a fly or insect to send a sensing signal to a solid state relay which then triggers the actuation circuit of the IPMC lobes to rapidly bend toward each other and close. The two lobes, which form the trap, are attached to the midrib common electrode which is conveniently termed the spine. The upper surface of each lobe is dished, and spaced along the free margins of the lobes with some 15-20 prong-like teeth. These are tough and pointed

  2. Ellis-van Creveld syndrome and Weyers acrodental dysostosis are caused by cilia-mediated diminished response to hedgehog ligands.

    PubMed

    Ruiz-Perez, Victor L; Goodship, Judith A

    2009-11-15

    Ellis-van Creveld syndrome (EvC; OMIM 225500) is a recessive disorder comprising chondrodysplasia, polydactyly, nail dysplasia, orofacial abnormalities and, in a proportion of patients, cardiovascular malformations. Weyers acrodental dysostosis (Weyers; OMIM 193530) is an allelic dominant disorder comprising polydactyly, nail dysplasia, and orofacial abnormalities. EvC results from loss-of-function mutations in EVC or EVC2, the phenotype associated with the mutations in these two genes being indistinguishable. Three convincing causative mutations have been identified in patients with Weyers acrodental dysostosis, which are clustered in the last coding exon of EVC2 and lead to production of a truncated protein lacking the final 43 amino acids. Localization and function of EVC and EVC2 are inferred from studying the murine orthologs. Both Evc and Evc2 proteins localize to the basal bodies of primary cilia and analysis of an Ellis-van Creveld mouse model, which includes the limb shortening and tooth abnormalities of EvC patients, has demonstrated Hedgehog signaling defects in the absence of Evc. The loss of Evc2 has not been studied directly, but Hedgehog signaling is impaired when a mutant murine Evc2 Weyer variant is expressed in vitro. We conclude that the phenotypic abnormalities in EvC and Weyers syndrome result from tissue specific disruption of the response to Hh ligands.

  3. On the mechanism of trap closure of Venus flytrap (Dionaea muscipula Ellis).

    PubMed

    Hodick, D; Sievers, A

    1989-08-01

    The rapid trap closure of Dionaea muscinula Ellis has been explained by either a loss of turgor pressure of the upper epidermis, which should thus become flexible, or by a sudden acid-induced wall loosening of the motor cells. According to our experiments both explanations are doubtful. Objections against the turgor mechanism come from the determination by extracellular measurements from the upper epidermis of action-potential amplitudes before and after trap closure. Neither time course nor amplitude of the action potentials are altered by trap closure. In contrast a rise in the apoplastic concentration of K(+) or Na(+), which are the only ions present in the trap in osmotically significant concentrations, from 1 to 10 mM reduces the action-potential amplitudes by 25% and 15%, respectively. Furthermore, after trap closure the upper epidermal cells retain a considerable cell sap osmolality of 0.41 mol·kg(-1) which equals that of the mesophyll cells as determined by incipient plasmolysis. A sudden cell-wall acidification causing movement is improbable since an acidification of the apoplast from pH 6 to pH 4 reduces action-potential amplitudes by 33% whereas the amplitudes measured extracellylarly from the mesophyll and lower epidermis remain unchanged by trap closure. In addition, buffering the apoplast at pH 6 does not prevent movement in traps which have been incised several times from the margin to the midrib to facilitate buffer diffusion into the mesophyll. Even an alkalinization of cell walls of plasmolysed leaf segments to pH 9 does not prevent considerable extensions of the mesophyll and subsequent movement of the specimens during deplasmolysis.These experiments make it very likely that the mesophyll cells are already extensible but are kept compressed in the open trap, thus developing tissue tension. The mechanism which prevents their extension as long as the trap is open can so far only be explained for traps which have been paralysed by a long

  4. Identification of one novel mutation in the EVC2 gene in a Chinese family with Ellis-van Creveld syndrome.

    PubMed

    Zhang, Zeng; Bao, Kun; He, Jin-Wei; Fu, Wen-Zhen; Zhang, Chang-Qing; Zhang, Zhen-Lin

    2012-12-15

    Ellis-van Creveld syndrome (EvC) is a rare autosomal recessive skeletal dysplasia characterized by short limbs, short ribs, postaxial polydactyly, and dysplastic nails and teeth. It is caused by biallelic mutations in the EVC or EVC2 gene. Here, we identified a novel nonsense mutation p.W828X (c.2484G>A) in exon 14 and a recurrent nonsense mutation p. R399X (c.1195C>T) in exon 10 of EVC2 gene in a Chinese boy with EvC. Identification of a novel genotype in EvC will provide clues to the phenotype-genotype relations and may assist not only in the clinical diagnosis of EvC but also in the interpretation of genetic information used for prenatal diagnosis and genetic counseling.

  5. Crocetin prevents retinal degeneration induced by oxidative and endoplasmic reticulum stresses via inhibition of caspase activity.

    PubMed

    Yamauchi, Mika; Tsuruma, Kazuhiro; Imai, Shunsuke; Nakanishi, Tomohiro; Umigai, Naofumi; Shimazawa, Masamitsu; Hara, Hideaki

    2011-01-10

    Crocetin is a carotenoid that is the aglicone of crocin, which are found in saffron stigmas (Crocus sativus L.) and gardenia fruit (Gardenia jasminoides Ellis). In this study, we investigated the effects of crocetin on retinal damage. To examine whether crocetin affects stress pathways, we investigated intracellular oxidation induced by reactive oxygen species, expression of endoplasmic reticulum (ER) stress-related proteins, disruption of the mitochondrial membrane potential (ΔΨ(m)), and caspases activation. In vitro, we employed cultured retinal ganglion cells (RGC-5, a mouse ganglion cell-line transformed using E1A virus). Cell damage was induced by tunicamycin or hydrogen peroxide (H(2)O(2)) exposure. Crocetin at a concentration of 3μM showed the inhibitory effect of 50-60% against tunicamycin- and H(2)O(2)-induced cell death and inhibited increase in caspase-3 and -9 activity. Moreover, crocetin inhibited the enzymatic activity of caspase-9 in a cell-free system. In vivo, retinal damage in mice was induced by exposure to white light at 8000lx for 3h after dark adaptation. Photoreceptor damage was evaluated by measuring the outer nuclear layer thickness at 5days after light exposure and recording the electroretinogram (ERG). Retinal cell damage was also detected with Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining at 48h after light exposure. Crocetin at 100mg/kg, p.o. significantly inhibited photoreceptor degeneration and retinal dysfunction and halved the expression of TUNEL-positive cells. These results indicate that crocetin has protective effects against retinal damage in vitro and in vivo, suggesting that the mechanism may inhibit increase in caspase-3 and -9 activities after retinal damage.

  6. Genetic and Epigenetic Approaches for the Possible Detection of Adulteration and Auto-Adulteration in Saffron (Crocus sativus L.) Spice.

    PubMed

    Soffritti, Giovanna; Busconi, Matteo; Sánchez, Rosa Ana; Thiercelin, Jean-Marie; Polissiou, Moschos; Roldán, Marta; Fernández, José Antonio

    2016-03-11

    Saffron (Crocus sativus L.) is very expensive and, because of this, often subject to adulteration. Modern genetic fingerprinting techniques are an alternative low cost technology to the existing chemical techniques, which are used to control the purity of food products. Buddleja officinalis Maxim, Gardenia jasminoides Ellis, Curcuma longa L., Carthamus tinctorius L. and Calendula officinalis L. are among the most frequently-used adulterants in saffron spice. Three commercial kits were compared concerning the ability to recover PCR-grade DNA from saffron, truly adulterated samples and possible adulterants, with a clear difference among them, mainly with the processed samples. Only one of the three kits was able to obtain amplifiable DNA from almost all of the samples, with the exception of extracts. On the recovered DNA, new markers were developed based on the sequence of the plastid genes matK and rbcL. These primers, mainly those developed on matK, were able to recognize saffron and the adulterant species and also in mixtures with very low percentages of adulterant. Finally, considering that the addition of different parts of saffron flowers is one of the most widespread adulterations, by analyzing the DNA of the different parts of the flower (styles, stamens and tepals) at the genetic and epigenetic level, we succeeded in finding differences between the three tissues that can be further evaluated for a possible detection of the kind of fraud.

  7. Crocetin protects ultraviolet A-induced oxidative stress and cell death in skin in vitro and in vivo.

    PubMed

    Ohba, Takuya; Ishisaka, Mitsue; Tsujii, Saori; Tsuruma, Kazuhiro; Shimazawa, Masamitsu; Kubo, Koya; Umigai, Naofumi; Iwawaki, Takao; Hara, Hideaki

    2016-10-15

    Crocetin, the aglycone of crocin, is a carotenoid found in fruits of gardenia (Gardeina jasminoides Ellis) and saffron (Crocus sativus L.). We investigated the protective effects of crocetin against ultraviolet-A (UV-A)-induced skin damage and explored the underlying mechanism. Human skin-derived fibroblasts cells (NB1-RGB) were damaged by exposure to UV-A irradiation (10J/cm(2)). Crocetin protected these cells against cell death and reduced the production of reactive oxygen species induced by UV-A irradiation. Crocetin treatment also suppressed induction of caspase-3 activation by UV-A irradiation. The effects of crocetin against oxidative stress were also examined by imaging of Keap1-dependent oxidative stress detector (OKD) mice. UV-A irradiation upregulated oxidative stress in the OKD mice skin, while crocetin administration (100mg/kg, p.o.) ameliorated this oxidative stress. Crocetin administration also decreased lipid peroxidation in the skin. These findings suggest that crocetin its observed protective effects against UV-A induced skin damage by reducing reactive oxygen species production and cell apoptosis.

  8. Gentiana scabra Bunge. Formula for Herpes Zoster: Biological Actions of Key Herbs and Systematic Review of Efficacy and Safety.

    PubMed

    Wang, Kaiyi; Coyle, Meaghan E; Mansu, Suzi; Zhang, Anthony Lin; Xue, Charlie Changli

    2017-03-01

    This study reviewed the biological action of key herbs and evaluated systematically the efficacy and safety of oral Gentiana formula for herpes zoster (HZ). Experimental studies relevant to HZ were identified in PubMed. Randomized controlled trials using Gentiana formula for HZ were identified from nine English and Chinese databases. The primary outcome was evaluation of pain. Potential risk of bias was assessed. Meta-analysis was conducted using mean difference or risk ratio with 95% confidence intervals. Key herbs Gentiana scabra Bunge, Gentiana triflora Pall, Scutellaria baicalensis Georgi, and Gardenia jasminoides Ellis have shown antiinflammatory actions through inhibition of inflammatory cytokines and pro-inflammatory enzymes. Twenty-six clinical studies, involving 2955 participants, were included. Modified Gentiana formula resolved pain earlier than pharmacotherapy when used alone or combined with topical Chinese herbal medicine. Incidence of postherpetic neuralgia was lower (risk ratio 0.14, 95% confidence interval 0.03 to 0.74) with modified Gentiana formula plus topical Chinese herbal medicine. Mild adverse events were reported. Antiinflammatory actions of key herbs of Gentiana formula may explain clinical benefit in hastening pain relief and decreasing postherpetic neuralgia. Few adverse events were reported. Findings were limited by study quality and diversity in intervention and comparator dosage. Copyright © 2017 John Wiley & Sons, Ltd.

  9. A cell-based high-throughput protocol to screen entry inhibitors of highly pathogenic viruses with Traditional Chinese Medicines.

    PubMed

    Yang, Yong; Cheng, Han; Yan, Hui; Wang, Peng-Zhan; Rong, Rong; Zhang, Ying-Ying; Zhang, Cheng-Bo; Du, Rui-Kun; Rong, Li-Jun

    2017-05-01

    Emerging viruses such as Ebola virus (EBOV), Lassa virus (LASV), and avian influenza virus H5N1 (AIV) are global health concerns. Since there is very limited options (either vaccine or specific therapy) approved for humans against these viruses, there is an urgent need to develop prophylactic and therapeutic treatments. Previously we reported a high-throughput screening (HTS) protocol to identify entry inhibitors for three highly pathogenic viruses (EBOV, LASV, and AIV) using a human immunodeficiency virus-based pseudotyping platform which allows us to perform the screening in a BSL-2 facility. In this report, we have adopted this screening protocol to evaluate traditional Chinese Medicines (TCMs) in an effort to discover entry inhibitors against these viruses. Here we show that extracts of the following Chinese medicinal herbs exhibit potent anti-Ebola viral activities: Gardenia jasminoides Ellis, Citrus aurantium L., Viola yedoensis Makino, Prunella vulgaris L., Coix lacryma-jobi L. var. mayuen (Roman.) Stapf, Pinellia ternata (Thunb.) Breit., and Morus alba L. This study represents a proof-of-principle investigation supporting the suitability of this assay for rapid screening TCMs and identifying putative entry inhibitors for these viruses. J. Med. Virol. 89:908-916, 2017. © 2016 Wiley Periodicals, Inc.

  10. Chemical profiling approach to evaluate the influence of traditional and simplified decoction methods on the holistic quality of Da-Huang-Xiao-Shi decoction using high-performance liquid chromatography coupled with diode-array detection and time-of-flight mass spectrometry.

    PubMed

    Yan, Xuemei; Zhang, Qianying; Feng, Fang

    2016-04-01

    Da-Huang-Xiao-Shi decoction, consisting of Rheum officinale Baill, Mirabilitum, Phellodendron amurense Rupr. and Gardenia jasminoides Ellis, is a traditional Chinese medicine used for the treatment of jaundice. As described in "Jin Kui Yao Lue", a traditional multistep decoction of Da-Huang-Xiao-Shi decoction was required while simplified one-step decoction was used in recent repsorts. To investigate the chemical difference between the decoctions obtained by the traditional and simplified preparations, a sensitive and reliable approach of high-performance liquid chromatography coupled with diode-array detection and electrospray ionization time-of-flight mass spectrometry was established. As a result, a total of 105 compounds were detected and identified. Analysis of the chromatogram profiles of the two decoctions showed that many compounds in the decoction of simplified preparation had changed obviously compared with those in traditional preparation. The changes of constituents would be bound to cause the differences in the therapeutic effects of the two decoctions. The present study demonstrated that certain preparation methods significantly affect the holistic quality of traditional Chinese medicines and the use of a suitable preparation method is crucial for these medicines to produce special clinical curative effect. This research results elucidated the scientific basis of traditional preparation methods in Chinese medicines.

  11. Protective effect of crocetin on hemorrhagic shock-induced acute renal failure in rats.

    PubMed

    Wang, Yunbo; Yan, Junling; Xi, Liang; Qian, Zhiyu; Wang, Zhenghong; Yang, Lina

    2012-07-01

    Multiple organ failure is a common outcome of hemorrhagic shock followed by resuscitation, and the kidney is one of the prime target organs involved. The main objective of the study was to evaluate whether crocetin, a natural product from Gardenia jasminoides Ellis, has beneficial effects on renal dysfunction caused by hemorrhagic shock and resuscitation in rats. Anesthetized rats were bled to reduce mean arterial blood pressure to 35 (SD, 5) mmHg for 60 min and then were resuscitated with their withdrawn shed blood and normal saline. Crocetin was administered via the duodenum at a dose of 50 mg/kg 40 min after hemorrhage. The increase in creatinine and blood urea nitrogen was significantly reduced at 2 h after hemorrhage and resuscitation in crocetin-treated rats. The increases in renal nitric oxide, tumor necrosis factor α, and interleukin 6 were also attenuated by crocetin. Hemorrhagic shock resulted in a significant elevation in malondialdehyde production and was accompanied by a reduction in total superoxide dismutase activity, activation of nuclear factor κB, and overexpression of inducible nitric oxide synthase. These changes were significantly attenuated by crocetin at 2 h after resuscitation. These results suggested that crocetin blocks inflammatory cascades by inhibiting production of reactive oxygen species and restoring superoxide dismutase activity to ameliorate renal dysfunction caused by hemorrhage shock and resuscitation.

  12. Identification of Novel Source of Resistance and Differential Response of Allium Genotypes to Purple Blotch Pathogen, Alternaria porri (Ellis) Ciferri

    PubMed Central

    Nanda, Satyabrata; Chand, Subodh Kumar; Mandal, Purander; Tripathy, Pradyumna; Joshi, Raj Kumar

    2016-01-01

    Purple blotch, caused by Alternaria porri (Ellis) Cifferi, is a serious disease incurring heavy yield losses in the bulb and seed crop of onion and garlic worldwide. There is an immediate need for identification of effective resistance sources for use in host resistance breeding. A total of 43 Allium genotypes were screened for purple blotch resistance under field conditions. Allium cepa accession ‘CBT-Ac77’ and cultivar ‘Arka Kalyan’ were observed to be highly resistant. In vitro inoculation of a selected set of genotypes with A. porri, revealed that 7 days after inoculation was suitable to observe the disease severity. In vitro screening of 43 genotypes for resistance to A. porri revealed two resistant lines. An additional 14 genotypes showed consistent moderate resistance in the field as well as in vitro evaluations. Among the related Allium species, A. schoenoprasum and A. roylei showed the least disease index and can be used for interspecific hybridization with cultivated onion. Differential reaction analysis of three A. porri isolates (Apo-Chiplima, Apn-Nasik, Apg-Guntur) in 43 genotypes revealed significant variation among the evaluated Allium species (P = 0.001). All together, the present study suggest that, the newly identified resistance sources can be used as potential donors for ongoing purple blotch resistance breeding program in India. PMID:27904458

  13. The importance of oral-clinical findings for the correct diagnosis of Ellis-van Creveld syndrome.

    PubMed

    Pedro, Rafael Lima; Andrade, Lucia Helena Raymundo; Maia, Lucianne Cople

    2011-01-01

    Ellis-van Creveld syndrome (EVC), also known as chondroectodermal dysplasia, is a rare autosomal recessive disorder. It is characterized by a variable spectrum of clinical findings, and the most common tetrad is chondrodystrophy, polydactyly, ectodermal dysplasia, and cardiac defects. Among the oral findings, number anomalies, peg-shaped teeth, and alterations in soft tissues are noteworthy. The aim of this paper is to report a case in which the diagnosis of EVC was possible only with the oral findings of a dentist and to relate the dental treatment performed. A 2-year-old girl was brought for dental care due to a lack of teeth. Her condition was initially diagnosed as thanatophoric dysplasia by her pediatrician. After evaluation of the oral manifestations, the dentist referred her to a geneticist, with the suggestion of EVC. The dental report, together with the systemic manifestations, allowed the geneticist to confirm the EVC diagnosis. The necessary dental procedures were performed, and the patient, now age 5, is still monitored by a multidisciplinary team.

  14. Disruption of sonic hedgehog signaling in Ellis-van Creveld dwarfism confers protection against bipolar affective disorder.

    PubMed

    Ginns, E I; Galdzicka, M; Elston, R C; Song, Y E; Paul, S M; Egeland, J A

    2015-10-01

    Ellis-van Creveld syndrome, an autosomal recessively inherited chondrodysplastic dwarfism, is frequent among Old Order Amish of Pennsylvania. Decades of longitudinal research on bipolar affective disorder (BPAD) revealed cosegregation of high numbers of EvC and Bipolar I (BPI) cases in several large Amish families descending from the same pioneer. Despite the high prevalence of both disorders in these families, no EvC individual has ever been reported with BPI. The proximity of the EVC gene to our previously reported chromosome 4p16 BPAD locus with protective alleles, coupled with detailed clinical observations that EvC and BPI do not occur in the same individuals, led us to hypothesize that the genetic defect causing EvC in the Amish confers protection from BPI. This hypothesis is supported by a significant negative association of these two disorders when contrasted with absence of disease (P=0.029, Fisher's exact test, two-sided, verified by permutation to estimate the null distribution of the test statistic). As homozygous Amish EVC mutations causing EvC dwarfism do so by disrupting sonic hedgehog (Shh) signaling, our data implicate Shh signaling in the underlying pathophysiology of BPAD. Understanding how disrupted Shh signaling protects against BPI could uncover variants in the Shh pathway that cause or increase risk for this and related mood disorders.

  15. Sequencing EVC and EVC2 identifies mutations in two-thirds of Ellis-van Creveld syndrome patients.

    PubMed

    Tompson, Stuart W J; Ruiz-Perez, Victor L; Blair, Helen J; Barton, Stephanie; Navarro, Victoria; Robson, Joanne L; Wright, Michael J; Goodship, Judith A

    2007-01-01

    Ellis-van Creveld syndrome (EvC) is caused by mutations in EVC and EVC2, genes in a divergent orientation separated by only 2.6 kb. We systematically sought mutations in both genes in a panel of 65 affected individuals to assess the proportion of cases resulting from mutations in each gene. We PCR amplified and sequenced the coding exons of both genes. We investigated mutations that could affect splicing by in vitro splicing assays and cDNA analysis. We have identified EVC mutations in 20 cases (31%); in all of these we have detected the mutation on each allele. We have identified EVC2 mutations in 25 cases (38%); in 22 of these we have isolated a mutation on each allele. The majority of the mutations introduce a premature termination codon. We sequenced the region between the two genes in 10 of the 20 cases in which we had not identified a mutation in either gene, revealing only one SNP that was not a common polymorphism. As we have not identified mutations in either gene in 20 cases (31%) it is possible that there is further genetic heterogeneity.

  16. Identification of Novel Source of Resistance and Differential Response of Allium Genotypes to Purple Blotch Pathogen, Alternaria porri (Ellis) Ciferri.

    PubMed

    Nanda, Satyabrata; Chand, Subodh Kumar; Mandal, Purander; Tripathy, Pradyumna; Joshi, Raj Kumar

    2016-12-01

    Purple blotch, caused by Alternaria porri (Ellis) Cifferi, is a serious disease incurring heavy yield losses in the bulb and seed crop of onion and garlic worldwide. There is an immediate need for identification of effective resistance sources for use in host resistance breeding. A total of 43 Allium genotypes were screened for purple blotch resistance under field conditions. Allium cepa accession 'CBT-Ac77' and cultivar 'Arka Kalyan' were observed to be highly resistant. In vitro inoculation of a selected set of genotypes with A. porri, revealed that 7 days after inoculation was suitable to observe the disease severity. In vitro screening of 43 genotypes for resistance to A. porri revealed two resistant lines. An additional 14 genotypes showed consistent moderate resistance in the field as well as in vitro evaluations. Among the related Allium species, A. schoenoprasum and A. roylei showed the least disease index and can be used for interspecific hybridization with cultivated onion. Differential reaction analysis of three A. porri isolates (Apo-Chiplima, Apn-Nasik, Apg-Guntur) in 43 genotypes revealed significant variation among the evaluated Allium species (P = 0.001). All together, the present study suggest that, the newly identified resistance sources can be used as potential donors for ongoing purple blotch resistance breeding program in India.

  17. Truncation and microdeletion of EVC/EVC2 with missense mutation of EFCAB7 in Ellis-van Creveld syndrome.

    PubMed

    Nguyen, Tran Quynh Nhu; Saitoh, Makiko; Trinh, Huu Tung; Doan, Nguyen Minh Thien; Mizuno, Yoko; Seki, Masafumi; Sato, Yusuke; Ogawa, Seishi; Mizuguchi, Masashi

    2016-09-01

    Ellis-van Creveld syndrome (EvC) is a ciliopathy with cardiac anomalies, disproportionate short stature, polydactyly, dystrophic nails and oral defects. To obtain further insight into the genetics of EvC, we screened EVC/EVC2 mutations in eight Vietnamese EvC patients. All the patients had a congenital heart defect with atypical oral and/or skeletal abnormalities. One had compound heterozygous EVC2 mutations: a novel mutation c.769G > T-p.E177X in exon 6 inherited from father and another previously reported c.2476C > T-p.R826X mutation in exon 14 inherited from mother. The EVC2 mRNA expression level was significantly lower in the patient and her parents compared to controls. Another case had a novel heterozygous EVC mutation (c.1717C > G-p.S572X) in exon 12, inherited from his father. Of note, the mother without any EVC mutation on Sanger sequencing showed a lower expression level of EVC mRNA compared with controls. SNP array analysis revealed that the patient and mother had a heterozygous 16.4 kb deletion in EVC. This patient also had a heterozygous novel variant in exon 9 of EFCAB7 (c.1171 T > C-p.Y391H), inherited from his father. The atypical cardiac phenotype of this patient and the father suggested that EFCAB7 may modify the phenotype by interacting with EVC. In conclusion, we detected two novel nonsense mutations and a partial deletion of EVC/EVC2 in two Vietnamese families with EvC. Moreover, we found in one family a missense mutation of EFCAB7, a possible modifier gene in EvC and its related disorders.

  18. OBSERVATIONAL UPPER BOUND ON THE COSMIC ABUNDANCES OF NEGATIVE-MASS COMPACT OBJECTS AND ELLIS WORMHOLES FROM THE SLOAN DIGITAL SKY SURVEY QUASAR LENS SEARCH

    SciTech Connect

    Takahashi, Ryuichi; Asada, Hideki

    2013-05-01

    The latest result in the Sloan Digital Sky Survey Quasar Lens Search (SQLS) has set the first cosmological constraints on negative-mass compact objects and Ellis wormholes. There are no multiple images lensed by the above two exotic objects for {approx}50, 000 distant quasars in the SQLS data. Therefore, an upper bound is put on the cosmic abundances of these lenses. The number density of negative-mass compact objects is n < 10{sup -8}(10{sup -4}) h {sup 3} Mpc{sup -3} at the mass scale |M| > 10{sup 15}(10{sup 12}) M{sub Sun }, which corresponds to the cosmological density parameter |{Omega}| < 10{sup -4} at the galaxy and cluster mass range |M| = 10{sup 12-15} M{sub Sun }. The number density of the Ellis wormhole is n < 10{sup -4} h {sup 3} Mpc{sup -3} for a range of the throat radius a = 10-10{sup 4} pc, which is much smaller than the Einstein ring radius.

  19. The Ellis Island Effect

    PubMed Central

    Husain, Fasahath; Veeranagouda, Yaligara; Boente, Renata; Tang, Kevin; Mulato, Gabriela; Wexler, Hannah M

    2014-01-01

    Objectives: Bacteroides fragilis, a Gram-negative anaerobic bacterium, is alternately a gut commensal or virulent pathogen and is an important reservoir for horizontal gene transfer (HGT) of bacterial resistance and virulence genes in the human gastrointestinal tract. We identified a unique conjugative transposon (CTn) in a multidrug resistant clinical isolate of B. fragilis (BF-HMW615); we named this element CTnHyb because it included a hybrid mosaic of foreign elements. This study reports the characterization of CTnHyb and discusses the potential impact on horizontal spread of resistance genes. Results: CTnHyb contains several efflux pump genes and several genes that confer or may confer antibiotic resistance to tetracycline, kanamycin, metronidazole and spectinomycin (truncated gene). CTnHyb also contains a mosaic of mobile elements from Gram-positive organisms. CTnHyb is easily transferred from BF-HMW615 (the original isolate) to BF638R (lab strain) and integrated into the BF638R chromosome. The “foreign” (from Gram-positive bacteria) nucleotide sequences within CTnHyb were > 99% preserved indicating that the gene acquisition from the Gram-positive bacteria was very recent. Conclusion: CTnHyb is a novel CTn residing in a multidrug resistant strain of B. fragilis. The global nature and wide phylogenetic reach of HGT means that any gene in any bacterium can potentially be mobilized. Understanding the mechanisms that drive the formation and transfer of these elements and, potentially, ways to limit the transfer are necessary to prevent a devastating spread of resistance elements. PMID:25165618

  20. Reaction to the Special Section on Supervision Research: Comment on Ellis et al (1996); Ladany et al (1996); Neufeldt et al (1996); and Worthen and McNeill (1996).

    ERIC Educational Resources Information Center

    Holloway, Elizabeth; Carroll, Michael

    1996-01-01

    Both the postpositivistic (Ellis, Ladany, Krengel, and Schult, 1996; Ladany, Hill, Corbett, and Nutt, 1996) and interpretive (Neufeldt, Karno, and Nelson, 1996; Worthen and McNeill, 1996) studies in this special section on supervision research are reviewed from the perspective of rigor and relevancy to the critical questions facing educators and…

  1. Therapeutic mechanism of Yīn-Chén-Hāo decoction in hepatic diseases

    PubMed Central

    Li, Jian-Yuan; Cao, Hong-Yan; Sun, Lin; Sun, Run-Fei; Wu, Chao; Bian, Yan-Qin; Dong, Shu; Liu, Ping; Sun, Ming-Yu

    2017-01-01

    Yīn-Chén-Hāo decoction (YCHD) is a traditional Chinese medicine formula composed of capillaris (Artemisia capillaris), gardenia (Gardenia jasminoides), and rhubarb (Rheum rhabarbarum) that is used for the treatment of damp-heat jaundice. In modern clinics, YCHD is mostly used for hepatic diseases. This review summarizes the biological activities of YCHD and its medical applications. The main active compounds of YCHD are chlorogenic acid, rhein, geniposide, emodin, and scoparone. The pharmacological actions of YCHD include inhibition of hepatic steatosis, apoptosis, necrosis, anti-inflammation, and immune regulation. YCHD could be developed as a new therapeutic strategy for the treatment of hepatic diseases. PMID:28275293

  2. Novel homozygous mutations in the EVC and EVC2 genes in two consanguineous families segregating autosomal recessive Ellis-van Creveld syndrome.

    PubMed

    Aziz, Abdul; Raza, Syed I; Ali, Salman; Ahmad, Wasim

    2016-01-01

    Ellis-van Creveld syndrome (EVC) is a rare developmental disorder characterized by short limbs, short ribs, postaxial polydactyly, dysplastic nails, teeth, oral and cardiac abnormalities. It is caused by biallelic mutations in the EVC or EVC2 gene, separated by 2.6 kb of genomic sequence on chromosome 4p16. In the present study, we have investigated two consanguineous families of Pakistani origin, segregating EVC in autosomal recessive manner. Linkage in the families was established to chromosome 4p16. Subsequently, sequence analysis identified a novel nonsense mutation (p.Trp234*) in exon 8 of the EVC2 gene and 15 bp duplication in exon 14 of the EVC gene in the two families. This further expands the mutations in the EVC or EVC2 genes resulting in the EVC syndrome.

  3. Baicalin and geniposide inhibit the development of atherosclerosis by increasing Wnt1 and inhibiting dickkopf-related protein-1 expression

    PubMed Central

    Wang, Bin; Liao, Ping-Ping; Liu, Li-Hua; Fang, Xin; Li, Wei; Guan, Si-Ming

    2016-01-01

    Background Our previous study showed that the combined Chinese herbs containing scutellaria baicalensis georgi and gardenia jasminoids ellis inhibited atherosclerosis. In this study, we sought to determine if baicalin and geniposide could inhibit atherosclerosis through Wnt1 and dickkopf-related protein-1 (DKK1). Methods The wild-type and ApoE−/− mice were treated with baicalin, geniposide, and baicalin plus geniposide daily by gavage for 12 weeks. Blood lipid levels were measured with an automatic biochemistry analyzer. Aortic atherosclerotic lesion areas were analyzed with Image-ProPlus software. The mRNA and protein expression of DKK1, Wnt1 and nuclear factor-κB (NF-κB) were measured with RT-PCR and Western Blot. Serum levels of interleukin-12 (IL-12) were quantified with ELISA. Results The baicalin or geniposide monotherapy as well as combination therapy inhibited the development of atherosclerotic lesions, increased Wnt1 and decreased DKK1 expression and elevated the ratio of Wnt1/DKK1 compared with high-lipid diet group. However, only baicalin or geniposide monotherapy decreased NF-κB expression. Moreover, baicalin and geniposide mono- or combination therapy lowered IL-12 levels. Geniposide reduced both serum total cholesterol and low density lipoprotein levels, while baicalin either alone or in combination with geniposide did not affect serum lipid levels. In human, umbilical vein endothelial cells stimulated by oxidized low density lipoprotein, baicalin and geniposide also increased Wnt1 and decreased DKK1 expression and elevated the ratio of Wnt1/DKK1. Conclusions Baicalin and geniposide exert inflammation-regulatory effects and may prevent atherosclerotic lesions through enhancing Wnt1 and inhibiting DKK1 expression. PMID:27928227

  4. An untargeted metabolomics-driven approach based on LC-TOF/MS and LC-MS/MS for the screening of xenobiotics and metabolites of Zhi-Zi-Da-Huang decoction in rat plasma.

    PubMed

    Wu, Huan; Li, Xixi; Yan, Xuemei; An, Li; Luo, Kaiwen; Shao, Mingjing; Jiang, Yue; Xie, Rui; Feng, Fang

    2015-11-10

    Zhi-Zi-Da-Huang decoction (ZZDHD), a typical traditional Chinese medicine prescription, is widely used in clinical practice for the treatment of alcoholic liver disease. However, due to lack of holistic metabolic research, the active ingredients of ZZDHD have not been fully elucidated. It entails a huge obstacle for the quality evaluation, pharmacokinetic studies and clinical-safe medication administration of ZZDHD. In this work, an untargeted metabolomics-driven approach was proposed to rapidly screen and characterize xenobiotics and related metabolites in vivo conducted by LC-TOF/MS and LC-QqQ/MS. The tR-m/z pairs which were present in the ZZDHD-dosed group and absent in the control group could be clearly displayed by XCMS Online platform combined with supervised orthogonal partial least squares discriminant analysis. Among them, a total of 61 ZZDHD-related xenobiotics and metabolites including 34 prototype components and 27 metabolites were rapidly identified or tentatively characterized in rat plasma. The results indicated that iridoid glycosides and monoterpenoids from Gardenia jasminoides Ellis, flavonoid glycosides from Citrus aurantium L., as well as anthraquinones from Rheum palmatum L. were the main absorbed chemical components of ZZDHD. Hydrolysis, glucuronidation and sulfation were the main metabolic pathways of ZZDHD in vivo. The present study provided a solid basis for further revealing the relationship between the xenobiotic metabolome and pharmacological activity of ZZDHD. In addition, the application of untargeted metabolomics-driven approach offers a fresh insight for rapid screening and identifying xenobiotics and metabolites of ZZDHD and other multiherb prescription.

  5. Geniposide plays an anti-inflammatory role via regulating TLR4 and downstream signaling pathways in lipopolysaccharide-induced mastitis in mice.

    PubMed

    Song, Xiaojing; Zhang, Wen; Wang, Tiancheng; Jiang, Haichao; Zhang, Zecai; Fu, Yunhe; Yang, Zhengtao; Cao, Yongguo; Zhang, Naisheng

    2014-10-01

    Geniposide is a medicine isolated from Gardenia jasminoides Ellis, which is a traditional Chinese herb that is widely used in Asia for the treatment of inflammation, brain diseases, and hepatic disorders. Mastitis is a highly prevalent and important infectious disease. In this study, we used a lipopolysaccharide (LPS)-induced mouse mastitis model and LPS-stimulated primary mouse mammary epithelial cells (mMECs) to explore the anti-inflammatory effect and the mechanism of action of geniposide. Using intraductal injection of LPS as a mouse model of mastitis, we found that geniposide significantly reduced the infiltration of inflammatory cells and downregulated the production of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and interleukin-6 (IL-6). To further investigate the anti-inflammatory mechanism, we used LPS-stimulated mMECs as an in vitro mastitis model. The results of enzyme-linked immunosorbent assay (ELISA) and quantitative real-time polymerase chain reaction (qRT-PCR) showed that geniposide inhibited the expression of TNF-α, IL-1β, and IL-6 in a dose-dependent manner. Western blot analysis demonstrated that geniposide could suppress the phosphorylation of inhibitory kappa B (IκBα), nuclear factor-κB (NF-κB), p38, extracellular signal-regulated kinase (ERK), and c-Jun N-terminal kinase (JNK). Geniposide also inhibited the expression of toll-like receptor 4 (TLR4) in the LPS-stimulated mMECs. In conclusion, geniposide exerted its anti-inflammatory effect by regulating TLR4 expression, which affected the downstream NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways. Thus, geniposide may be a potential drug for mastitis therapy.

  6. Geniposide ameliorates TNBS-induced experimental colitis in rats via reducing inflammatory cytokine release and restoring impaired intestinal barrier function.

    PubMed

    Xu, Bin; Li, Yan-Li; Xu, Ming; Yu, Chang-Chun; Lian, Meng-Qiao; Tang, Ze-Yao; Li, Chuan-Xun; Lin, Yuan

    2017-03-06

    Geniposide is an iridoid glycosides purified from the fruit of Gardenia jasminoides Ellis, which is known to have antiinflammatory, anti-oxidative and anti-tumor activities. The present study aimed to investigate the effects of geniposide on experimental rat colitis and to reveal the related mechanisms. Experimental rat colitis was induced by rectal administration of a TNBS solution. The rats were treated with geniposide (25, 50 mg·kg(-1)·d(-1), ig) or with sulfasalazine (SASP, 100 mg·kg(-1)·d(-1), ig) as positive control for 14 consecutive days. A Caco-2 cell monolayer exposed to lipopolysaccharides (LPS) was used as an epithelial barrier dysfunction model. Transepithelial electrical resistance (TER) was measured to evaluate intestinal barrier function. In rats with TNBS-induced colitis, administration of geniposide or SASP significantly increased the TNBS-decreased body weight and ameliorated TNBS-induced experimental colitis and related symptoms. Geniposide or SASP suppressed inflammatory cytokine (TNF-α, IL-1β, and IL-6) release and neutrophil infiltration (myeloperoxidase activity) in the colon. In Caco-2 cells, geniposide (25-100 μmol/L) ameliorated LPS-induced endothelial barrier dysfunction via dose-dependently increasing transepithelial electrical resistance (TER). The results from both in vivo and in vitro studies revealed that geniposide down-regulated NF-κB, COX-2, iNOS and MLCK protein expression, up-regulated the expression of tight junction proteins (occludin and ZO-1), and facilitated AMPK phosphorylation. Both AMPK siRNA transfection and AMPK overexpression abrogated the geniposide-reduced MLCK protein expression, suggesting that geniposide ameliorated barrier dysfunction via AMPK-mediated inhibition of the MLCK pathway. In conclusion, geniposide ameliorated TNBS-induced experimental rat colitis by both reducing inflammation and modulating the disrupted epithelial barrier function via activating the AMPK signaling pathway..

  7. Ellis-van Creveld syndrome in a fetus with rhizomelia and polydactyly. Report of a case diagnosed by genetic analysis, and correlation with pathological andradiologic findings.

    PubMed

    Peraita-Ezcurra, Milena; Martínez-García, Mónica; Ruiz-Pérez, Víctor L; Sánchez-Gutiérrez, María Eugenia; Fenollar-Cortés, María; Vélez-Monsalve, Camilo; Ramos-Corrales, Carmen; Pastor, Ignacio; Santonja, Carlos; Trujillo-Tiebas, María José

    2012-05-10

    Ellis-van Creveld syndrome is an autosomal recessive disorder mainly characterized by a disproportionate limb dwarfism, chondroectodermal dysplasia, congenital heart disease, postaxial polydactyly, and dysplastic fingernails and teeth. Only 300 cases have been published worldwide. We report a 21-week fetus with rhizomelia and polydactyly detected. Gross photographs, radiologic studies and pathological study were performed leading to the clinico-pathological suspicion of EvC. DNA from fresh fetal tissue was extracted for sequencing the EVC and EVC2 genes. p.W215X and p.R677X mutations were identified in the EVC2 gene in the fetal sample. Parental sample analysis showed the p.W215X mutation to be inherited from the mother and the p.R677X mutation from the father. The clinical information is essential not only to arrive at a correct diagnosis in fetuses with pathologic ultrasound findings, but also to offer a proper genetic counseling to the parents and their relatives.

  8. Two novel heterozygous mutations of EVC2 cause a mild phenotype of Ellis-van Creveld syndrome in a Chinese family.

    PubMed

    Shen, Wenjing; Han, Dong; Zhang, Jin; Zhao, Hongshan; Feng, Hailan

    2011-09-01

    Ellis-van Creveld syndrome (EvC, chondroectodermal dysplasia; OMIM 225500) is an autosomal recessive skeletal dysplasia with associated multisystem involvement. The syndrome is characterized by short limbs, short ribs, postaxial polydactyly, dysplastic nails, and abnormal teeth. Congenital heart defects occur in 50-60% of cases. In this study, we report EvC in a 6-year-old Chinese girl with hypodontia and polydactyly, mild short stature, and abnormalities of the knee joints. No signs of short ribs, narrow thorax, or congenital heart defects were found in this patient. The EvC phenotype shares some similarity with Weyers acrofacial dysostosis (Weyer; OMIM 193530), an autosomal dominant disorder clinically characterized by mild short stature, postaxial polydactyly, nail dystrophy, and dysplastic teeth. Mutations in EVC or EVC2 are associated with both EvC syndrome and Weyers acrodental dysostosis, but the two conditions differ in the severity of the phenotype and their pattern of inheritance. In this study, two novel heterozygous EVC2 mutations, IVS5-2A > G and c.2653C > T (Arg885X), were identified in the patient. The IVS5-2A > G mutation was inherited from the patient's mother and the c.2653C > T from her father. Her parents have no phenotypic symptoms similar to those of the patient. These findings extend the mutation spectrum of this malformation syndrome and provide the possibility of prenatal diagnosis for future offspring in this family.

  9. A Turkish family with Ellis-van Creveld syndrome in six siblings; linkage analysis on 4p16 region (D4S3360-D4S2366).

    PubMed

    Cağdaş, D N; Parlar, A I; Pac, A; Tutun, U; Balci, S

    2008-01-01

    We present a Turkish family and their 6 children, consecutively affected by Ellis-van Creveld (EVC) Syndrome. Four of the affected children died in the postnatal period, and 2 of them had been admitted to the pediatric cardiology department for their cardiologic evaluation. Since they had the features of the EVC Syndrome, linkage analysis was performed with the polymorphic markers, D4S3360-D4S2366, selected from 4p 16 locus. There was complete segregation between the disease and marker allels and the two affected siblings were homozygote for the polymorphic markers, as expected in autosomal recessive inheritance. The diagnosis of EVC Syndrome was confirmed by this molecular analysis. Two cases with EVC were presented in this report. Case 1 had partial abnormal pulmonary venous return and pulmonary stenosis additional to ostium primum atrial septal defect and mitral cleft. Partial abnormal pulmonary venous return and pulmonary stenosis were previously not reported with EVC Syndrome. Postaxial polydactyly phenotype of the Case 2 differs from her brother's. There is bifid 5th metacarpal and unilateral (L) bifid middle and distal phalanges resembling syndactyly.

  10. The influence of secretion elicitors and external pH on the kinetics of D-alanine uptake by the trap lobes of Dionaea muscipula Ellis (Venus's Flytrap).

    PubMed

    Rea, P A; Whatley, F R

    1983-08-01

    Simple kinetic techniques were used to examine the mechanism of D-alanine uptake by the adaxial surfaces of the trap lobes of Dionaea muscipula Ellis (Venus's Flytrap.) On the basis of these analyses, the uptake of D-alanine was found to depend on the time during which the trap lobes were inoculated with elicitors of secretion before excision and measurement of uptake. Disks taken from traps that had not been subjected to a preceding period of inoculation with secretion elicitors showed a low basal rate of uptake which was neither pH-dependent nor exhibited saturation with respect to external D-alanine concentration. Disks from preinoculated traps, on the other hand, displayed an enhanced rate of uptake which showed both pH-dependence and saturation with respect to external D-alanine concentration. The capacity for enhanced uptake was lost upon prolonged inoculation or when inoculation was stopped. Of the compounds tested, only elicitors of secretion caused an enhancement of uptake. The enhanced rate of D-alanine uptake is temperature-sensitive with a Q10 characteristic of a mediated process. Uncouplers cause an instantaneous abolition of uptake whereas the effects of terminal-oxidase inhibitors are time-dependent. The pH-dependence of uptake is inferred to result from an increased affinity of the carrier system for D-alanine at low pH values. Although the ionic state of D-alanine is relatively unaffected over the pH range examined, a decrease in the external pH from 6.0 to 3.8 decreases the apparent K m for uptake by four-fold but increases V max by only 30%. It is concluded that the acid secreted by the digestive glands of Dionaea plays a direct role in facilitating the uptake of amino acids from the trap cavity.

  11. Tanning Effects of Aluminum -Genipin or -Vegetable Tannin Combinations

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Genipin, a naturally occurring protein crosslinking agent, isolated from the fruit of Gardenia jasmindides Ellis, is beginning to replace glutaraldehyde as a fixative for biological tissues. Earlier research in this laboratory demonstrated that when hide powder was first tanned with 8% aluminum and...

  12. Ellis-Van Creveld Dysplasia

    MedlinePlus

    ... We Offer > Medical Specialties & Services > Skeletal Dysplasia Medical Services Skeletal Dysplasia Definitions Achondroplasia Campomelic Dysplasia Cartilage Hair Hypoplasia Diastrophic Dysplasia ...

  13. Ellis-van Creveld syndrome

    MedlinePlus

    ... Exams and Tests Signs of this condition include: Growth hormone deficiency Heart defects, such as a hole in ... More Autosomal recessive Breathing difficulty Congenital heart disease Growth hormone deficiency - children Review Date 8/1/2015 Updated ...

  14. Early Treatment in Shock

    DTIC Science & Technology

    2011-06-01

    jasminoides Ellis). It is com- monly sold in the United States as an herbal supplement . In terms of crocetin’s fundamental mode of action in host... supplementation 15 can be beneficial in ameliorating the tissue damage produced following experimental 16 hemorrhagic shock. In the present investigation...experimental rat model of hemorrhagic shock. Our studies were designed to test two 19 hypotheses. First, L-arginine supplementation during resuscitation will

  15. Effect of crocetin on vascular smooth muscle cells migration induced by advanced glycosylation end products.

    PubMed

    Xiang, Min; Yang, Runlin; Zhang, Yaqin; Wu, Pingping; Wang, Lizhen; Gao, Zhenyu; Wang, Jianmei

    2017-02-13

    Crocetin is a major active constituent of Gardenia jasminoides J. Ellis, and can aid in the prevention of cardiovascular disease. The effect and possible mechanism of crocetin on the migration of vascular smooth muscle cells (VSMCs) induced by advanced glycosylation end products (AGEs) were investigated. VSMCs were pre-incubated with or without crocetin and exposed to AGEs subsequently. The invasion of the cells was investigated using a 24-well Cell Invasion Chamber. The anti-proliferative activity of crocetin was evaluated by MTT assay and VSMCs cell-cycle distribution was examined by flow cytometry. Cytokine TNF-α and IL-6 secreted by VSMCs and the amount of matrix metalloproteinase MMP-2 and MMP-9 in the culture supernatant were detected by ELISA. The expression level of RAGE (AGEs receptor), in cells was analyzed by western blot. The results demonstrated that AGEs increased about two-fold migration of VSMCs compared with control (OD=0.778±0.191 vs OD=0.413±0.214, P<0.01), and the proliferation increased by about 20% (OD=0.335±0.043 vs OD=0.281±0.037, P<0.01). Pre-treatment with crocetin (1.0μM) or RAGE antibody (10μg/ml) could inhibit the AGEs triggered migration of VSMCs obviously. Furthermore, both crocetin and RAGE antibody inhibited the increase of RAGE protein in VSMCs stimulated by AGEs. The levels of TNF-α and IL-6 decreased in the crocetin (1.0μM) pre-treated group compared to the AGEs (without pre-treated) group (37.60±3.08pg/ml vs 46.59±1.92pg/ml, 32.11±4.69pg/ml vs 49.99±8.84pg/ml, respectively). Crocetin (1.0μM) also reduced the value of MMP-2 and MMP-9 compared with the AGEs group (2.81±0.35ng/ml vs 6.40±0.85ng/ml, 2.69±0.25ng/ml vs 4.32±0.57ng/ml, respectively). In summary, crocetin inhibits the migration of VSMCs induced by AGEs through RAGE-dependent signaling pathway. And it is meaningful to diabetic vascular complications.

  16. Specific variants in WDR35 cause a distinctive form of Ellis-van Creveld syndrome by disrupting the recruitment of the EvC complex and SMO into the cilium

    PubMed Central

    Caparrós-Martín, José A.; De Luca, Alessandro; Cartault, François; Aglan, Mona; Temtamy, Samia; Otaify, Ghada A.; Mehrez, Mennat; Valencia, María; Vázquez, Laura; Alessandri, Jean-Luc; Nevado, Julián; Rueda-Arenas, Inmaculada; Heath, Karen E.; Digilio, Maria Cristina; Dallapiccola, Bruno; Goodship, Judith A.; Mill, Pleasantine; Lapunzina, Pablo; Ruiz-Perez, Victor L.

    2015-01-01

    Most patients with Ellis-van Creveld syndrome (EvC) are identified with pathogenic changes in EVC or EVC2, however further genetic heterogeneity has been suggested. In this report we describe pathogenic splicing variants in WDR35, encoding retrograde intraflagellar transport protein 121 (IFT121), in three families with a clinical diagnosis of EvC but having a distinctive phenotype. To understand why WDR35 variants result in EvC, we analysed EVC, EVC2 and Smoothened (SMO) in IFT-A deficient cells. We found that the three proteins failed to localize to Wdr35−/− cilia, but not to the cilium of the IFT retrograde motor mutant Dync2h1−/−, indicating that IFT121 is specifically required for their entry into the ciliary compartment. Furthermore expression of Wdr35 disease cDNAs in Wdr35−/− fibroblasts revealed that the newly identified variants lead to Hedgehog signalling defects resembling those of Evc−/− and Evc2−/− mutants. Together our data indicate that splicing variants in WDR35, and possibly in other IFT-A components, underlie a number of EvC cases by disrupting targeting of both the EvC complex and SMO to cilia. PMID:25908617

  17. Specific variants in WDR35 cause a distinctive form of Ellis-van Creveld syndrome by disrupting the recruitment of the EvC complex and SMO into the cilium.

    PubMed

    Caparrós-Martín, José A; De Luca, Alessandro; Cartault, François; Aglan, Mona; Temtamy, Samia; Otaify, Ghada A; Mehrez, Mennat; Valencia, María; Vázquez, Laura; Alessandri, Jean-Luc; Nevado, Julián; Rueda-Arenas, Inmaculada; Heath, Karen E; Digilio, Maria Cristina; Dallapiccola, Bruno; Goodship, Judith A; Mill, Pleasantine; Lapunzina, Pablo; Ruiz-Perez, Victor L

    2015-07-15

    Most patients with Ellis-van Creveld syndrome (EvC) are identified with pathogenic changes in EVC or EVC2, however further genetic heterogeneity has been suggested. In this report we describe pathogenic splicing variants in WDR35, encoding retrograde intraflagellar transport protein 121 (IFT121), in three families with a clinical diagnosis of EvC but having a distinctive phenotype. To understand why WDR35 variants result in EvC, we analysed EVC, EVC2 and Smoothened (SMO) in IFT-A deficient cells. We found that the three proteins failed to localize to Wdr35(-/-) cilia, but not to the cilium of the IFT retrograde motor mutant Dync2h1(-/-), indicating that IFT121 is specifically required for their entry into the ciliary compartment. Furthermore expression of Wdr35 disease cDNAs in Wdr35(-/-) fibroblasts revealed that the newly identified variants lead to Hedgehog signalling defects resembling those of Evc(-/-) and Evc2(-/-) mutants. Together our data indicate that splicing variants in WDR35, and possibly in other IFT-A components, underlie a number of EvC cases by disrupting targeting of both the EvC complex and SMO to cilia.

  18. Long interspersed nuclear element-1 (LINE1)-mediated deletion of EVC, EVC2, C4orf6, and STK32B in Ellis-van Creveld syndrome with borderline intelligence.

    PubMed

    Temtamy, Samia A; Aglan, Mona S; Valencia, Maria; Cocchi, Guido; Pacheco, Maria; Ashour, Adel M; Amr, Khalda S; Helmy, Sanaa M H; El-Gammal, Mona A; Wright, Michael; Lapunzina, Pablo; Goodship, Judith A; Ruiz-Perez, Victor L

    2008-07-01

    Previous work has shown Ellis-van Creveld (EvC) patients with mutations either in both alleles of EVC or in both alleles of EVC2. We now report affected individuals with the two genes inactivated on each allele. In a consanguineous pedigree diagnosed with EvC and borderline intelligence, we detected a 520-kb homozygous deletion comprising EVC, EVC2, C4orf6, and STK32B, caused by recombination between long interspersed nuclear element-1 (LINE-1 or L1) elements. Patients homozygous for the deletion are deficient in EVC and EVC2 and have no increase in the severity of the EvC typical features. Similarly deletion carriers demonstrate absence of digenic inheritance in EvC. Further, the phenotype of these patients suggests that the EVC-STK32B deletion also leads to mild mental retardation and reveals that loss of the novel genes C4orf6 and STK32B causes at most mild mental deficit. In an EvC compound heterozygote of different ethnic origin we identified the same LINE-to-LINE rearrangement due to a different recombination event. These findings highlight the importance of L1 repetitive sequences in human genome architecture and disease.

  19. Spontaneous Electrical Activity of Dionaea muscipula.

    PubMed

    Balotin, N M; Dipalma, J R

    1962-12-21

    Instillation of four to six drops of 3-percent saline in the leaf trap of Dionaea muscipula Ellis causes the appearance of a series of spontaneous action potentials. Mechanical stimulation of the sensitive leaf hair elicits only a single response. Immersion in 3-percent, but not in 1-percent, saline effects a loss of weight in Dionaea but not in the leaves of gardenia or geranium.

  20. Ecology and behavior of Pezothrips kellyanus (Thysanoptera: Thripidae) on citrus.

    PubMed

    Vassiliou, V A

    2010-02-01

    The most common thrips species found in Cyprus citrus orchards between 2003 and 2008 were Pezothrips kellyanus (Bagnall) (Thysanoptera: Thripidae), Frankliniella occidentalis (Pergande) (Thysanoptera: Thripidae), and Thrips tabaci (Lindeman) (Thysanoptera: Thripidae). Only Pezothrips kellyanus, Kelly's citrus thrips (KCT) causes feeding damage on citrus fruits in Cyprus. KCT adults prefer to concentrate mostly in the northern and eastern sides of both lemon and grapefruit canopies. The attractiveness of white, sky blue, marine blue, and yellow color to KCT was evaluated. White was found to be the most attractive color to adults of KCT, F. occidentalis, and T. tabaci. A range of incidental and breeding host plants grown within and outside citrus orchards in Cyprus were identified. KCT adults were found on flowers of all citrus varieties, and various other flowering plants including Malva nicaeensis, Malva silvestris, Sinapis alba, Oxalis pes-caprae, Calendula arvensis, Urospermum picroides, Jasminum officinale, Gardenia jasminoides, Jasminum sambac, Prunus dulcis, Mangifera indica, Persea americana, and Eriobotrya japonica. KCT larvae were found only on lemon, grapefruit, Jasmine spp., and Gardenia flowers.

  1. Charge induced closing of Dionaea muscipula Ellis trap.

    PubMed

    Volkov, Alexander G; Adesina, Tejumade; Jovanov, Emil

    2008-11-01

    In terms of bioelectrochemistry, Venus flytrap responses can be considered in three stages: stimulus perception, electrical signal transmission, and induction of mechanical and biochemical responses. When an insect touches the trigger hairs, these mechanosensors generate receptor potentials, which induce solitary waves activating the motor cells. We found that the electrical charge injected between a midrib and a lobe closes the Venus flytrap leaf by activating motor cells without mechanical stimulation of trigger hairs. The mean electrical charge required for the closure of the Venus flytrap leaf is 13.6 muC. To close the trap, electrical charge can be submitted as a single charge or applied cumulatively by small portions during a short period of time. Ion channel blocker such as Zn(2+) as well as an uncoupler CCCP, dramatically decreases the speed of the trap closing a few hours after treatment of the soil. This effect is reversible. After soil washing by distilled water, the closing time of Venus flytrap treated by CCCP or ZnCl(2) decreases back from 2-5 s to 0.3 s, but higher electrical charge is needed for trap closure. The mechanism behind closing the upper leaf of Venus flytrap is discussed.

  2. Jessica Ann Ellis Gold Star Fathers Act of 2010

    THOMAS, 111th Congress

    Sen. Wyden, Ron [D-OR

    2010-07-26

    12/17/2010 By Senator Lieberman from Committee on Homeland Security and Governmental Affairs filed written report. Report No. 111-374. (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  3. Genetics Home Reference: Ellis-van Creveld syndrome

    MedlinePlus

    ... genes are thought to help regulate the Sonic Hedgehog signaling pathway. This pathway plays roles in cell ... condition. Studies suggest that they prevent normal Sonic Hedgehog signaling in the developing embryo, disrupting the formation ...

  4. Simultaneous Determination of Catalpol, Aucubin, and Geniposidic Acid in Different Developmental Stages of Rehmannia glutinosa Leaves by High Performance Liquid Chromatography

    PubMed Central

    Wang, Yanjie; Liao, Dengqun; Qin, Minjian

    2016-01-01

    Although R. glutinosa roots are currently the only organ source in clinics, its leaves are a potential supplement for the roots especially in extraction of some important bioactive compounds. Our early work found that the contents of catalpol and total iridoid glycosides varied among different developmental stages of R. glutinosa leaves. Aucubin and geniposidic acid, the abundant major bioactive compounds in Eucommia ulmoides and Gardenia jasminoides, respectively, were found present in R. glutinosa roots, however, and have not been analyzed in its leaves. In this paper, we aimed to determine contents of these three iridoid glycosides in different developmental stages of R. glutinosa leaves using the optimized HPLC-UV conditions. Our results showed that aucubin and GPA in R. glutinosa leaves were much lower than catalpol and showed the increasing trend with the leaf development, which was different from catalpol. This work provided the important information for future exploitation of R. glutinosa leaves as a potential supplement for its roots in extraction of some important bioactive compounds and studying the relationship of aucubin and catalpol metabolism. PMID:27429834

  5. Norartocarpetin from a folk medicine Artocarpus communis plays a melanogenesis inhibitor without cytotoxicity in B16F10 cell and skin irritation in mice

    PubMed Central

    2013-01-01

    Background Many natural products used in preventive medicine have also been developed as cosmeceutical ingredients in skin care products, such as Scutellaria baicalensis and Gardenia jasminoides. Norartocarpetin is one of the antioxidant and antityrosinase activity compound in Artocarpus communis; however, the cytotoxicity, skin irritation and antimelanogenesis mechanisms of norartocarpetin have not been investigated yet. Methods In the present study, cell viability in vitro and skin irritation in vivo are used to determine the safety of norartocarpetin. The melanogenesis inhibition of norartocarpetin was determined by cellular melanin content and tyrosinase in B16F10 melanoma cell. Moreover, we examined the related-melanogenesis protein by western blot analysis for elucidating the antimelanogenesis mechanism of norartocarpin. Results The result of the present study demonstrated that norartocarpetin not only present non-cytotoxic in B16F10 and human fibroblast cells but also non-skin irritation in mice. Moreover, our result also first found that norartocarpetin downregulated phospho-cAMP response element-binding (phospho-CREB) and microphthalmia-associated transcription factor (MITF) expression, which in turn decreased both synthesis of tyrosinases (TRP-1 and TRP-2) and cellular melanin content. This process is dependent on norartocarpetin phosphorylation by mitogen-activated protein kinases such as phospho-JNK and phospho-p38, and it results in decreased melanogenesis. Conclusion The present study suggests that norartocarpetin could be used as a whitening agent in medicine and/or cosmetic industry and need further clinical study. PMID:24325567

  6. Simultaneous Determination of Catalpol, Aucubin, and Geniposidic Acid in Different Developmental Stages of Rehmannia glutinosa Leaves by High Performance Liquid Chromatography.

    PubMed

    Wang, Yanjie; Liao, Dengqun; Qin, Minjian; Li, Xian'en

    2016-01-01

    Although R. glutinosa roots are currently the only organ source in clinics, its leaves are a potential supplement for the roots especially in extraction of some important bioactive compounds. Our early work found that the contents of catalpol and total iridoid glycosides varied among different developmental stages of R. glutinosa leaves. Aucubin and geniposidic acid, the abundant major bioactive compounds in Eucommia ulmoides and Gardenia jasminoides, respectively, were found present in R. glutinosa roots, however, and have not been analyzed in its leaves. In this paper, we aimed to determine contents of these three iridoid glycosides in different developmental stages of R. glutinosa leaves using the optimized HPLC-UV conditions. Our results showed that aucubin and GPA in R. glutinosa leaves were much lower than catalpol and showed the increasing trend with the leaf development, which was different from catalpol. This work provided the important information for future exploitation of R. glutinosa leaves as a potential supplement for its roots in extraction of some important bioactive compounds and studying the relationship of aucubin and catalpol metabolism.

  7. Anti-Adipogenic Effects of Ethanol Extracts Prepared from Selected Medicinal Herbs in 3T3-L1 Cells

    PubMed Central

    Park, Min-Jun; Song, Ji-Hye; Shon, Myung-Soo; Kim, Hae Ok; Kwon, O Jun; Roh, Seong-Soo; Kim, Choon Young; Kim, Gyo-Nam

    2016-01-01

    Obesity is a major risk factor for various metabolic diseases such as cardiovascular disease, hypertension, and type 2 diabetes mellitus. In this study, we prepared ethanol extracts from Agastache rugosa (ARE), Chrysanthemum zawadskii (CZE), Mentha arvensis (MAE), Perilla frutescens (PFE), Leonurus sibiricus (LSE), Gardenia jasminoides (GJE), and Lycopus coreanus (LCE). The anti-oxidant and anti-adipogenic effects were evaluated. The IC50 values for ascorbic acid and LCE against 2,2-diphenyl-1-picrylhydrazyl radicals were 246.2 μg/mL and 166.2 μg/mL, respectively, followed by ARE (186.6 μg/mL), CZE (198.6 μg/mL), MAE (337.1 μg/mL), PFE (415.3 μg/mL), LSE (548.2 μg/mL), and GJE (626.3 μg/mL). In non-toxic concentration ranges, CZE had a strong inhibitory effect against 3T3-L1 adipogenes (84.5%) than those of the other extracts. Furthermore, the anti-adipogenic effect of CZE is largely limited in the early stage of adipogenesis, and we revealed that the inhibitory role of CZE in adipogenesis is required for the activation of Wnt signaling. Our results provide scientific evidence that the anti-adipogenic effect of CZE can be applied as an ingredient for the development of functional foods and nutri-cosmetics for obesity prevention. PMID:27752499

  8. Genipin attenuates lipopolysaccharide-induced persistent changes of emotional behaviors and neural activation in the hypothalamic paraventricular nucleus and the central amygdala nucleus.

    PubMed

    Araki, Ryota; Hiraki, Yosuke; Yabe, Takeshi

    2014-10-15

    Sickness behavior is a series of behavioral and psychological changes that develop in inflammatory disease, including infections and cancers. Administration of the bacterial endotoxin lipopolysaccharide (LPS) induces sickness behavior in rodents. Genipin, an aglycon derived from an iridoid glycoside geniposide extracted from the fruit of Gardenia jasminoides, has anti-inflammatory and antidepressant activities. However, the effects of genipin on inflammation-induced changes in emotional behaviors are unknown. In this study, we examined the effects of genipin on LPS-induced inflammation in BV-2 cells and sickness behavior in mice. Pretreatment with genipin inhibited LPS-induced increases in NO production and reduced the mRNA levels of inflammation-related genes (iNOS, COX-2, IL-1β and IL-6) in BV-2 cells. Oral administration of genipin ameliorated LPS-induced depressive-like behavior in the forced swim test and social behavior deficits 24h after LPS administration in mice. LPS-induced expression of mRNAs for inflammation-related genes and the number of c-fos immunopositive cells decreased in the paraventricular nucleus (PVN) of the hypothalamus and the central nucleus of the amygdala (CeA), suggesting that genipin attenuates LPS-induced changes of emotional behaviors through inhibition of neural activation and inflammatory responses in the PVN and CeA. These novel pharmacological effects of genipin may be useful for treatment of patients with sickness behavior.

  9. Baicalin and geniposide attenuate atherosclerosis involving lipids regulation and immunoregulation in ApoE-/- mice.

    PubMed

    Liao, Pingping; Liu, Lihua; Wang, Bin; Li, Wei; Fang, Xin; Guan, Siming

    2014-10-05

    Baicalin and geniposide, which are respectively isolated from Scutellariae radix and Gardenia jasminoides, have been known to exhibit a number of pharmacological effects, including anti-inflammatory and anti-oxidant. Here, we primarily aimed to observe the protective effects of these two Chinese herbs on inhibiting the development of atherosclerosis in apolipoprotein E knockout mice via lipids regulation and immunoregulation. After the ApoE-/- mice with high-cholesterol diet had received 12-weeks׳ oral administration of either baicalin or geniposide (100 mg/kg), atherosclerotic plaque areas in aorta were measured and exhibited a prominent decrease in the treated mice. We then assayed serum lipids levels, serum Treg-cell-associated cytokines (TGF-β1 and IL-10) and the frequency of splenic Treg cells. We found that geniposide notably decreased serum TC and LDL-c. Both baicalin and geniposide treated mice showed much more splenic Treg cells and the correlated cytokines (TGF-β1 and IL-10). Foxp3, as the marker of Treg cell, was detected in atherosclerotic lesions, and we found that Foxp3 expression at both mRNA and protein levels was up-regulated in addition to increased Foxp3 positive Treg cells detected by immunohistochemistry in baicalin or geniposide treated mice. In conclusion, baicalin and geniposide up-regulated the expression of foxp3, promoted the number and function of Treg cells and ameliorated the atherosclerotic lesions progression partly through lipids regulation and immunoregulation.

  10. [Selection and purification potential evaluation of woody plant in vertical flow constructed wetlands in the subtropical area].

    PubMed

    Chen, Yong-Hua; Wu, Xiao-Fu; Hao, Jun; Chen, Ming-Li; Zhu, Guang-Yu

    2014-02-01

    In order to solve the problem that wetland herbaceous plants tend to die during winter in subtropics areas, selection and purification potential evaluation experiments were carried out by introducing into the constructed wetlands 16 species of woody wetland plants. Cluster analysis was performed by including the morphological characteristics, physiological characteristics, as well as nitrogen and phosphorus accumulation of the woody wetland plants. The results indicated that there were significant differences among the tested woody plants in their survival rate, height increase, root length increase and vigor, Chlorophyll content, Superoxide dismutase, Malonaldehyde, Proline, Peroxidase, biomass, average concentration and accumulation of nitrogen and phosphorus. Based on the established evaluation system, the tested plants were clustered into 3 groups. The plants in the 1st group possessing high purification potentials are Nerium oleander and Hibiscus syriacus. Those in the 2nd group possessing moderate purification potentials are Trachycarpus fortune, Llex latifolia Thunb., Gardenia jasminoides, Serissa foetida and Ilex crenatacv Convexa. And those in the 3rd group with low purification potentials are Jasminum udiflorum, Hedera helix, Ligustrum vicaryi, Ligustrum lucidum, Buxus sempervives, Murraya paniculata, Osmanthus fragrans, Mahoniafortune and Photinia serrulata.

  11. Can ethnopharmacology contribute to the development of anti-fertility drugs?

    PubMed

    Pei-Gen, X; Nai-Gong, W

    1991-04-01

    China, one of the developing countries with approx. one-fifth of the world population, has been making great efforts in controlling her population size. One of the efforts being stressed is to look into the practicability of employing Chinese herbal medicine for fertility control. The rich ethnopharmacological descriptions in the ancient books of herbal remedy and those scattered in the folklore medicine contribute the possibility of this approach. After a discussion concerning the facets of antifertility drugs linked with male or female fertility regulation, several selected examples are presented, which include yuehchukene (isolated from Murraya paniculata), pseudolarix acids A and B (from Pseudolarix kaempferi), mardekoside A (from Mardenia koi), gardenic acid and gardenodic acid A (from Gardenia jasminoides) as early pregnancy terminating agent, for fertility regulation in females; whereas gossypol (from cottonseed oil) and total glycosides of Tripterygium wilfordii (GTW) as antispermatogenic agent for fertility regulation in males. Further research and development strategies of antifertility drugs from herbal medicines have also been discussed based on a collective research data in this field worldwide.

  12. Immigration beyond Ellis Island: Suggestions for Teaching about Immigration in the Now

    ERIC Educational Resources Information Center

    Hossain, Kazi I.

    2014-01-01

    America's history books abound with stories of immigrants who contributed to the development of this country. In terms of social studies curriculum, all states require schools to teach about immigration. However, the question is how to teach this topic in a manner that will give students--elementary through high school--a better understanding of…

  13. Acid phosphatase localization in the digestive glands of Dionaea muscipula Ellis flytraps.

    PubMed

    Henry, Y; Steer, M W

    1985-04-01

    The intracellular localization of acid phosphatases in stimulated digestive glands of Dionaea flytraps has been studied to provide evidence for the route taken by this enzyme during secretion. Previous studies have either included or excluded a role for the dictyosomes in this pathway. Both p-nitrophenyl phosphate and beta-glycerophosphate were used as substrates, and both gave similar localization patterns. Unstimulated glands contained little phosphatase activity in the endomembrane system, whereas 24 and 48 hr after stimulation, heavy deposits of lead were located in the endoplasmic reticulum cisternae, including the nuclear envelope, the dictyosome cisternae, and secretory vesicles. Since dictyosome activation, as judged by the presence of secretory vesicles in the cytoplasm, also coincides with gland stimulation, we conclude that secretion of the hydrolase enzymes occurs via this route and not, as suggested elsewhere, via direct endoplasmic reticulum to plasma membrane connections.

  14. Polarity in mechanoreceptor cells of trigger hairs of Dionaea muscipula Ellis.

    PubMed

    Buchen, B; Hensel, D; Sievers, A

    1983-08-01

    Both the apical and the basal cell poles of the sensory cells in trigger hairs of Dionaea muscipula are structured identically. A complex of concentrically arranged endoplasmic reticulum cisternae occupies each of the poles. One to four vacuoles are enclosed within the central cisterna and contain polyphenols (deposits of "tannin"). Structural polarity, whether symmetric or asymmetric, as well as the occurrence of abundant endoplasmic reticulum and numerous mitochondria are characteristics of the perception cells of most animals and plants.

  15. The nature of the stimuli causing digestive juice secretion in Dionaea muscipula Ellis (venus's flytrap).

    PubMed

    Robins, R J

    1976-01-01

    An investigation into the stimuli of the secretory system in the carnivorous plant Dionaea muscipula is presented. Secretion of fluid and protein are both stimulated by various nitrogenous small molecules. These secretions are studied as a function of time. A new method is described for the collection of secreted juice. Significant differences are found between the quantities of fluid and protein produced in response to different stimuli. The results are discussed in comparison to the mammalian gastro-intestinal secretory systems.

  16. New Kind of Ellis Island as Second-Generation Immigrants Land on College Campuses

    ERIC Educational Resources Information Center

    Hohn, Marcia Drew; Mohammed, Denzil

    2012-01-01

    Demographics in American higher education are changing dramatically. A recent study by the Migration Policy Institute (MPI) reveals that 11.3 million people ages 16 to 26 (one in four) are first- and second-generation immigrants. Moreover, the report continues, between 1995 and 2010, immigrant-origin youth accounted for half of all growth in the…

  17. 78 FR 74009 - Safety Zone; Nike Fireworks, Upper New York Bay, Ellis Island, NY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-10

    ... is necessary to ensure the safety of vessels and spectators from hazards associated with fireworks... to Mariners and marine information broadcasts. If the COTP determines that the regulated area...

  18. A Resource Guide for Celebrating the Statue of Liberty and Ellis Island, 1986. Bulletin 1783.

    ERIC Educational Resources Information Center

    Kerr, Myrtle; Cookston, James S.

    Compiled to help celebrate the 100th anniversary of the Statue of Liberty, this selection of books, periodicals, audiovisuals, and other educational resources was intended to help stimulate discussion, promote projects, and create awareness of the Statue of Liberty Centennial. Listed are 24 books, 18 magazine articles, and 3 films about the Statue…

  19. Do People Grow on Family Trees? Genealogy for Kids & Other Beginners. The Official Ellis Island Handbook.

    ERIC Educational Resources Information Center

    Wolfman, Ira

    This book offers a comprehensive method for those who seek to discover their own family history. Techniques used for study are pedigree charts, family group sheets, reading relationship charts, and the study of historical immigration movements. Information on how to research family genealogies by way of the family Bible, handling photographs, tape…

  20. Case Summary: Settlement Reached at Middlefield-Ellis-Whisman (MEW) Study Area to Address TCE Contamination

    EPA Pesticide Factsheets

    Case summary of the first amended consent decree with Intel Corporation and Raytheon Company to address trichloroethylene (TC) contamination in residential and commercial buildings in Mountain View, California

  1. "Their Experience Is the Immigrant Experience": Ellis Island, Documentary Film, and Rhetorically Reversible Whiteness

    ERIC Educational Resources Information Center

    Irwin, Meryl J.

    2013-01-01

    Political advocates on the ideological right have long taken seriously what their counterparts on the left have not: white racialized affect. As left activists and scholars have alternately lamented and raged over the steady creep of the "middle" to the "right," they have documented in detail the outcomes of whites' refusal to engage in "genuine"…

  2. Gravity Currents: In the Environment and the Laboratory, Ellis Horwood Series in Environmental Sciences

    NASA Astrophysics Data System (ADS)

    Csanady, G. T.

    There are books and courses on experimental physics, thorough and rigorous, which contain only simple formulae and use only elementary algebra. The subject is explained in lucid and precise language, with the help of many sketches, photos, and diagrams. The book under review belongs to this genre and is in fact one of its most successful members.About half of the book is devoted to the description of a variety of natural phenomena in which gravity currents play an important role. The class of gravity currents is taken to be quite broad, to include almost any kind of quasi-horizontal motion caused by density differences. The range of natural phenomena surveyed is correspondingly great, from tidal bores through thunderstorms to the eruption of Mount St. Helens. The atmospheric examples are especially thorough and interesting. The broad panorama certainly brings home to the reader the many ways in which fluids (including fluidized rock) can move under the influence of gravity. However, not all of the examples show typical gravity behavior, nor are they all treated with equal thoroughness. The Gulf Stream is mentioned, and the variability of its position is shown in an illustration, but this is not connected with anything typical of gravity currents, nor is the important interplay between Earth rotation and such large-scale “gravity currents” (if one insists on calling them that) at all adequately explained.

  3. Immigration: From the Founding of Virginia to the Closing of Ellis Island. An Eyewitness History.

    ERIC Educational Resources Information Center

    Wepman, Dennis

    It can be said that U.S. immigration started in 1607, when the first settlers joined the original colonists on the shores of the United States. Since then, people of every nation, ethnicity, and class have come to the United States, looking for freedom, prosperity, and stability. While originally immigrants flowed freely into the United States,…

  4. Genus III. Turneriella Levett, Morey, Galloway, Steigerwalt, Ellis 2005, 1497AL

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Turneriella are morphologically similar to Leptospira. They are unique within the Leptospiraceae by having distinct DNA sequence composition as demonstrated by DNA hybridization analysis, and a unique 16S rRNA sequence profile. In addition, they are distinguished by having a single periplasmic fla...

  5. Ichnology and paleosubstrates of Austin Chalk (Cretaceous) outcrops: Southern Dallas and Ellis Counties, Texas

    SciTech Connect

    Dawson, W.C. ); Reaser, D.F. )

    1991-03-01

    Ichnofossils are abundant in outcrops of the Austin Chalk near Waxahachie, Texas (designated site of the Super-Conducting Super Collider). The abundance and diversity of ichnofossils in Austin strata contrast with the paucity of other macrofossils, except large inoceramids. The lower Austin Chalk (Coniacian) disconformably overlies the Eagle Ford Shale (Turonian). Planolites, Thalassinoides, and Chondrites are conspicuous in the lower Austin. Some lower Austin strata contain well-preserved burrows having menicus fillings. However, most lower Austin ichnofossils are poorly preserved and have compacted. The middle Austin Marl and upper Austin Chalk (Santonain) contain Planolites, Chondrites, Thalassinoides, and Pseudobilobites. Several thin, intensely burrowed, Fe-stained, horizons within the middle Austin represent omission surfaces having postomission Thalassinoides. The upper Austin disconformably underlies the Taylor Marl (Campanian). The Austin-Taylor contact is a Rhizocorallium-infested omission surface overlain by a condensed bed of phosphatic and pyritic bioclasts. Upper Austin occurrences of Rhizocorallium and Pseudobilobites are unique for North American Cretaceous chalks. Based on cross-cutting relationships and differences in morphology, diameter, and burrow-filling sediments, numerous ichnospecies of Thalassinoides are discernable throughout the Austin. Variations in preservation quality exhibited by successive generations of ichnofossils record progressive changes in substrate consistency. Earliest formed burrows have diffuse outlines representing an initial thixotropic (softground) Austin substrate. Subsequent generations of burrows have more distinct outlines recording a gradual increase in substrate firmness. Paleo-firmgrounds are common in Austin outcrops; evidence of hardgrounds is lacking. The Thalassinoides-dominated Austin ichnoassemblage represents an inner shelf paleoenvironment.

  6. From Ellis Island to LAX: Immigrant Prospects in the American City.

    ERIC Educational Resources Information Center

    Waldinger, Roger

    1996-01-01

    Argues that the economic and political structures of the immigrant receiving areas shape immigrant trajectories. Provides a comparative discussion that examines how the distinctive urban contexts of immigrant receiving areas, such as New York City and Los Angeles, differ in shaping immigrants' future prospects in assimilating within their new…

  7. A Comparison of Rational Emotive Therapy and Tibetan Buddhism: Albert Ellis and the Dalai Lama

    ERIC Educational Resources Information Center

    Holt, Susan A; Austad, Carol Shaw

    2013-01-01

    This article explores conceptual and methodological similarities between Rational Emotive Behavior Therapy (REBT) and Tibetan Buddhism (TB). The authors examine some of the values and concepts they share. They compare the two systems on a number of issues: philosophical underpinnings, concepts of what causes human psychopathology, techniques to…

  8. Chlorogenic acid inhibits osteoclast differentiation and bone resorption by down-regulation of receptor activator of nuclear factor kappa-B ligand-induced nuclear factor of activated T cells c1 expression.

    PubMed

    Kwak, Sung Chul; Lee, Cheol; Kim, Ju-Young; Oh, Hyun Mee; So, Hong-Seob; Lee, Myeung Su; Rho, Mun Chual; Oh, Jaemin

    2013-01-01

    Excessive osteoclastic bone resorption plays a critical role in inflammation-induced bone loss such as rheumatoid arthritis and periodontal bone erosion. Therefore, identification of osteoclast targeted-agents may be a therapeutic approach to the treatment of pathological bone loss. In this study, we isolated chlorogenic acid (CGA) from fructus of Gardenia jasminoides to discover anti-bone resorptive agents. CGA is a polyphenol with anti-inflammatory and anti-oxidant activities, however, its effects on osteoclast differentiation is unknown. Thus, we investigated the effect of CGA in receptor activator of nuclear factor-kappa B (NF-κB) ligand (RANKL)-induced osteoclast differentiation and RANKL signaling. CGA dose-dependently inhibited RANKL-mediated osteoclast differentiation in bone marrow macrophages (BMMs) without any evidence of cytotoxicity. CGA inhibited the phosphorylation of p38, Akt, extracellular signal-regulated kinase (ERK), and inhibitor of nuclear factor-kappa B (IκB), and IκB degradation by RANKL treatment. CGA suppressed the mRNA expression of nuclear factor of activated T cells c1 (NFATc1), TRAP and OSCAR in RANKL-treated bone marrow macrophages (BMMs). Also, overexpression of NFATc1 in BMMs blocked the inhibitory effect of CGA on RANKL-mediated osteoclast differentiation. Furthermore, to evaluate the effects of CGA in vivo, lipopolysaccharide (LPS)-induced bone erosion study was carried out. CGA remarkably attenuated LPS-induced bone loss based on micro-computed tomography and histologic analysis of femurs. Taken together, our findings suggest that CGA may be a potential treatment option for osteoclast-related diseases with inflammatory bone destruction.

  9. Saco River-Camp Ellis Harbor, Saco, Maine. Small Navigation Project, Detailed Project Report and Environmental Assessment.

    DTIC Science & Technology

    1981-12-01

    Evaluating and comparing the economic, social and environmental impacts of the alternative plans. 5. Determining if improvements are feasible and, if so...recommending improvements to anchorage facilities that are economically feasible, socially beneficial and environmentally acceptable. Although this study... market in local residents, tourists, restaurants, and retail stores all over the northeastern United States. The major commercial activity at Camp

  10. Is Angel Island the Ellis Island of the West? Teaching Multiple Perspective-Taking in American Immigration History

    ERIC Educational Resources Information Center

    Ciardiello, A. Vincent

    2012-01-01

    Education in the twenty-first century requires that all students learn the social studies skills that help them understand the complex issues related to civic ideals and practices. One of these skills is developing multiple perspective-taking. Many educators believe that this critical thinking ability is not only for upper level students but also…

  11. On the mechanism underlying photosynthetic limitation upon trigger hair irritation in the carnivorous plant Venus flytrap (Dionaea muscipula Ellis).

    PubMed

    Pavlovic, Andrej; Slováková, L'udmila; Pandolfi, Camilla; Mancuso, Stefano

    2011-03-01

    Mechanical stimulation of trigger hairs on the adaxial surface of the trap of Dionaea muscipula leads to the generation of action potentials and to rapid leaf movement. After rapid closure secures the prey, the struggle against the trigger hairs results in generation of further action potentials which inhibit photosynthesis. A detailed analysis of chlorophyll a fluorescence kinetics and gas exchange measurements in response to generation of action potentials in irritated D. muscipula traps was used to determine the 'site effect' of the electrical signal-induced inhibition of photosynthesis. Irritation of trigger hairs and subsequent generation of action potentials resulted in a decrease in the effective photochemical quantum yield of photosystem II (Φ(PSII)) and the rate of net photosynthesis (A(N)). During the first seconds of irritation, increased excitation pressure in photosystem II (PSII) was the major contributor to the decreased Φ(PSII). Within ∼1 min, non-photochemical quenching (NPQ) released the excitation pressure at PSII. Measurements of the fast chlorophyll a fluorescence transient (O-J-I-P) revealed a direct impact of action potentials on the charge separation-recombination reactions in PSII, although the effect seems to be small rather than substantial. All the data presented here indicate that the main primary target of the electrical signal-induced inhibition of photosynthesis is the dark reaction, whereas the inhibition of electron transport is only a consequence of reduced carboxylation efficiency. In addition, the study also provides valuable data confirming the hypothesis that chlorophyll a fluorescence is under electrochemical control.

  12. [Control of chlorophyll a synthesis by phytochrome and cryptochrome in the red alga Corallina elongata Ellis et Soland].

    PubMed

    López-Figueroa, F; Niell, F X

    1988-09-01

    Chlorophyll a synthesis in the red alga Corallina elongata is controlled by phytochrome and by a specific blue light photoreceptor. Although the estimated photoequilibrium of phytochrome is similar in blue and red light, the amount of chlorophyll accumulated is greater in blue light, which implies the action of cryptochrome, according to the criteria for the specific blue light photoreceptor involvement. The amount of chlorophyll synthesized is greater when the level of photoequilibrium approaches 65% (in blue and red light) than with higher levels (72.7% in white light and 70.8% in green light). The action of phytochrome is demonstrated by the induction of chlorophyll synthesis after red pulses and the reversion after far red pulses. The reversion is not complete but the percentage of reversibility is high (85-90%). The amount of chlorophyll accumulated is greater in darkness after the application of red light pulses than in white light after the same light pulses. The induction of chlorophyll synthesis is greater after red pulses than after continuous red light. The existence of a fast destruction of chlorophyll in continuous light is observed. This destruction is greater in the high photoequilibrium of phytochrome (70-72%). The turnover times and the induction mechanism of chlorophyll synthesis must be very fast. This indicates the existence of a possible rapid adaptation to the change in light quality and intensity in the marine system.

  13. Society News: RAS Awards 2011; Prof. Richard Ellis; Prof. Eberhard Grün; Prof. Gilles Chabrier; Prof. Roger Searle;

    NASA Astrophysics Data System (ADS)

    2011-02-01

    Each year the RAS recognizes outstanding achievement in astronomy and geophysics by the award of medals and prizes. Candidates are nominated by Fellows and the awards made by a committee of Fellows, ensuring that these scientists have earned the respect and admiration of their peers in the research community.

  14. The 2nd United Kingdom Extracellular Vesicle Forum Meeting Abstracts: 15 December 2015, Hadyn Ellis Building, Cardiff University.

    PubMed

    Clayton, Aled; Lawson, Charlotte; Gardiner, Chris; Harrison, Paul; Carter, David

    2016-01-01

    The UK Extracellular Vesicles (UKEV) Forum meetings were born of the realization that there were a number of UK laboratories studying extracellular vesicle biology and using similar techniques but without a regular national meeting dedicated to EVs at which to share their findings. This was compounded by the fact that many of these labs were working in different fields and thus networking and sharing of ideas and best practice was sometimes difficult. The first workshop was organized in 2013 by Dr Charlotte Lawson, under the auspices of the Society for Endocrinology, led to the founding of the UKEV Forum and the organization of a British Heart Foundation sponsored 1-day conference held in London in December 2014. Although growing in size every year, the central aims of these workshops have remained the same: to provide a forum for discussion and exchange of ideas, to allow young scientists to present their data in the form of short talks and poster presentations and to discuss their work with more established scientists in the field. Here we include the presented abstracts for the 2015 1-day conference hosted by Cardiff University. This meeting was attended by approximately 130 delegates throughout the United Kingdom, but also attended by delegates from Belgium, Netherlands, France, Ireland and other nations. The day composed of plenary presentations from Prof Matthias Belting, Lund University, Sweden and Dr Guillaume van Niel, Institut Curie, Paris together with 10 short presentations from submitted abstracts. The topics covered were broad, with sessions on Mechanisms of EV production, EVs in Infection, EVs in Cancer and in Blood and Characterizing EVs in Biological fluids. This hopefully gives a reflection of the range of EV-related studies being conducted currently in the UK. There were also 33 poster presentations equally broad in subject matter. The organizers are grateful to the Life Science Research Network Wales - a Welsh government-funding scheme that part-sponsored the conference. We are also grateful to commercial sponsors, and 3 paid-presentations are included in the abstracts. The UK EV Forum is expected to become an established annual event held at different Universities across the UK and continue to attract increasing delegate numbers and abstract submissions. We look forward to the next planned conference, which will be hosted by David Carter and his colleagues at Oxford Brookes University on 13th December 2016.

  15. 75 FR 17125 - Foreign-Trade Zone 113-Ellis County, Texas, Application for Reorganization under Alternative Site...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE... May 14, 2010. Submissions (original and one electronic copy) shall be addressed to the Board's Executive Secretary at: Foreign-Trade Zones Board, U.S. Department of Commerce, Room 2111, 1401...

  16. The Maurice Ellis lecture for 1986. The responsibility of emergency medicine towards the prevention of road accidents.

    PubMed Central

    Rutherford, W H

    1986-01-01

    It is argued that doctors who work in accident and emergency departments should play their part in road accident prevention. It is suggested that this might be done in the field of research, by direct action, through education of the public and by influencing legislation. Examples are given of both small and simple, and major national research projects based in accident and emergency departments. The type of direct action envisaged is modelled on the work of Dr Hayle Hadeson in preventing accidents to children. Examples of the education of the public are drawn from publicity work in the seat-belt campaign, and experiences of lobbying members of parliament in relation to seat-belt legislation are described. The relative under-funding of trauma research compared with cancer of heart disease research is seen as a measure of society's lack of interest in accident prevention, and colleagues unchallenged to do more to alter this situation. PMID:3768120

  17. Genipin is active via modulating monoaminergic transmission and levels of brain-derived neurotrophic factor (BDNF) in rat model of depression.

    PubMed

    Wang, Q-S; Tian, J-S; Cui, Y-L; Gao, S

    2014-09-05

    Genipin, an important bioactive component from Gardenia jasminoides Eills, was demonstrated to possess antidepressant-like effects in a previous study. However, the molecular mechanism of antidepressant-like effects on genipin was not clear. The present study aimed to investigate the possible mechanism of antidepressant-like effects on genipin with a chronic unpredictable mild stress (CUMS)-induced depression model in rats. In CUMS-induced depressive rats, bodyweight and 1% sucrose consumption decreased significantly compared with the normal control group. Furthermore, these changes could be significantly reversed by genipin application. The levels of 5-hydroxytryptamine (5-HT), norepinephrine (NE) in the hippocampus decreased and the level of 5-hydroxyindole acetic acid (5-HIAA) increased in the CUMS-induced depressive rats. However, pre-treatments with genipin significantly increased the levels of 5-HT, NE and decreased the level of 5-HIAA in the hippocampus. The concentration of cAMP in the hippocampus was increased by genipin compared to the CUMS-exposed model group. The mRNA expressions of 5-hydroxytryptamine 1A receptor (5-HT1AR), cAMP response element binding protein (CREB) and brain-derived neurotrophic factor (BDNF) in rats were decreased exposed to CUMS, which were reversed by genipin-treated rats exposed to CUMS. Compared to the CUMS-exposed model group, the mRNA expression of 5-hydroxytryptamine 2A receptor (5-HT(2A)R) was decreased significantly by genipin-treated rats. The mRNA and protein expression of CREB, BDNF were increased in genipin-treated rats compared to the CUMS-exposed model group. Moreover, the levels of corticosterone in serum were decreased by genipin-treated compared to the CUMS-exposed model group. These results suggest that the possible mechanism of antidepressant-like effects on genipin, at least in one part, resulted from monoaminergic neurotransmitter system and the potential dysfunctional regulation of the post-receptor signaling

  18. Abundance of cysteine endopeptidase dionain in digestive fluid of Venus flytrap (Dionaea muscipula Ellis) is regulated by different stimuli from prey through jasmonates.

    PubMed

    Libiaková, Michaela; Floková, Kristýna; Novák, Ondřej; Slováková, L'udmila; Pavlovič, Andrej

    2014-01-01

    The trap of the carnivorous plant Venus flytrap (Dionaea muscipula) catches prey by very rapid closure of its modified leaves. After the rapid closure secures the prey, repeated mechanical stimulation of trigger hairs by struggling prey and the generation of action potentials (APs) result in secretion of digestive fluid. Once the prey's movement stops, the secretion is maintained by chemical stimuli released from digested prey. We investigated the effect of mechanical and chemical stimulation (NH4Cl, KH2PO4, further N(Cl) and P(K) stimulation) on enzyme activities in digestive fluid. Activities of β-D-glucosidases and N-acetyl-β-D-glucosaminidases were not detected. Acid phosphatase activity was higher in N(Cl) stimulated traps while proteolytic activity was higher in both chemically induced traps in comparison to mechanical stimulation. This is in accordance with higher abundance of recently described enzyme cysteine endopeptidase dionain in digestive fluid of chemically induced traps. Mechanical stimulation induced high levels of cis-12-oxophytodienoic acid (cis-OPDA) but jasmonic acid (JA) and its isoleucine conjugate (JA-Ile) accumulated to higher level after chemical stimulation. The concentration of indole-3-acetic acid (IAA), salicylic acid (SA) and abscisic acid (ABA) did not change significantly. The external application of JA bypassed the mechanical and chemical stimulation and induced a high abundance of dionain and proteolytic activity in digestive fluid. These results document the role of jasmonates in regulation of proteolytic activity in response to different stimuli from captured prey. The double trigger mechanism in protein digestion is proposed.

  19. Abundance of Cysteine Endopeptidase Dionain in Digestive Fluid of Venus Flytrap (Dionaea muscipula Ellis) Is Regulated by Different Stimuli from Prey through Jasmonates

    PubMed Central

    Libiaková, Michaela; Floková, Kristýna; Novák, Ondřej; Slováková, L'udmila; Pavlovič, Andrej

    2014-01-01

    The trap of the carnivorous plant Venus flytrap (Dionaea muscipula) catches prey by very rapid closure of its modified leaves. After the rapid closure secures the prey, repeated mechanical stimulation of trigger hairs by struggling prey and the generation of action potentials (APs) result in secretion of digestive fluid. Once the prey's movement stops, the secretion is maintained by chemical stimuli released from digested prey. We investigated the effect of mechanical and chemical stimulation (NH4Cl, KH2PO4, further N(Cl) and P(K) stimulation) on enzyme activities in digestive fluid. Activities of β-D-glucosidases and N-acetyl-β-D-glucosaminidases were not detected. Acid phosphatase activity was higher in N(Cl) stimulated traps while proteolytic activity was higher in both chemically induced traps in comparison to mechanical stimulation. This is in accordance with higher abundance of recently described enzyme cysteine endopeptidase dionain in digestive fluid of chemically induced traps. Mechanical stimulation induced high levels of cis-12-oxophytodienoic acid (cis-OPDA) but jasmonic acid (JA) and its isoleucine conjugate (JA-Ile) accumulated to higher level after chemical stimulation. The concentration of indole-3-acetic acid (IAA), salicylic acid (SA) and abscisic acid (ABA) did not change significantly. The external application of JA bypassed the mechanical and chemical stimulation and induced a high abundance of dionain and proteolytic activity in digestive fluid. These results document the role of jasmonates in regulation of proteolytic activity in response to different stimuli from captured prey. The double trigger mechanism in protein digestion is proposed. PMID:25153528

  20. Modeling of ground-water flow in subsurface Austin Chalk and Taylor marl in Ellis County, Texas, near the superconducting super collider site

    SciTech Connect

    Mace, R.E. . Bureau of Economic Geology)

    1993-02-01

    Numerical models are useful tools for developing an understanding of ground-water flow in sparsely characterized low-permeability aquifers. Finite-difference, cross-sectional models of Cretaceous chalk and marl formations near the Superconducting Super Collider (SSC) were constructed using MODFLOW to evaluate ground-water circulation paths and travel times. Weathered and fractured zones with enhanced permeability were included to assess the effect these features had on flow paths and times. Pump tests, slug tests, packer tests, core tests, and estimates were used to define hydraulic properties for model input. The model was calibrated with water-level data from monitor wells and from wire-line piezometers near a test shaft excavated by the SSC project. A ratio of vertical-to-horizontal permeability of 0.0085 was estimated through model calibration. A chalk-to-marl permeability ratio of 18 was needed to reproduce artesian head in a well completed in chalk beneath marl. Hydraulic head distributions and ground-water flow paths reflected local, intermediate, and regional flow systems with recharge beneath upland surface-water divides and discharge in valleys. Most of the flow (99%) occurred in the weathered zone, with average residence times of 5 to 10 years. Residence time in unweathered chalk bedrock was substantially longer, at an average of 1.7 Ma. As expected, the model demonstrated that deep and rapid ground-water circulation might occur in fracture zones. Particle paths calculated using MODPATH showed that ground-water travel times from recharge areas to the SSC subsurface facilities might be 20 to 60 years where flow is through fracture zones.

  1. National Dam Safety Program. Ellis Lake Dam (MO 31067), Mississippi - Kaskaskia - St. Louis River Basin, Perry County, Missouri. Phase I Inspection Report.

    DTIC Science & Technology

    1981-03-01

    If a publication has a title in a foreign language , translate the title into English and follow the English translation with the title in the...original language . Make every effort to simplify the title before publication. Block 5. Type of Report and Period Covered. Indicate here whether report is...Block Key Words. Select terms or short phrases that identify the principal subjects covered in the report, and are sufficiently specific and

  2. The Study of Two Psychotherapy Approaches (Rogers Self Theory and Ellis Rational Theory) in Improvement of Bowen Self-differentiation and Intimacy

    PubMed Central

    Yousefi, Naser; Kiani, Mohammad Ali

    2014-01-01

    Objective: To compare the effectiveness of rational, behavioral and emotive therapy (REBT) and person-centered therapy (PCT) on self-differentiation and intimacy among divorce clients. Methods: In quasi-experimental study, 42 divorce clients (both males and females) who presented to the Counsling Center of Sanandaj, Iran were sampled. They were categorized into three groups of PCT, REBT, and control group (each group contained 14 subjects). The recovery indices (dependent variables) employed were the subject of self-differentiation and intimacy, which were measured twice before and after intervention of Differentiation of Self Inventory-2 (DSI-2) and intimacy. The therapy involved 8 one-hour sessions. It was held twice a week and therapeutic effects were traced after 8 months. Results: The results showed that REBT and PCT were effective on self-differentiation scale and intimacy. Also they were influential in recovery self-differentiation scale and intimacy follow up stage. Conclusion: REBT and PCT were effective on self-differentiation and its subscales (Emotional reactivity, “I” position, Emotional cut off and Fusion with other) and general intimacy. Declaration of interest: None. PMID:24995028

  3. Base Exterior Architecture Plan: Naval Ocean Systems Center Hawaii Laboratory, Oahu, Hawaii

    DTIC Science & Technology

    1990-02-01

    cuttings Sedum confusum 1 Gal or 2-1/2 Gal Hibiscus rosa-sinensis Existig trees to be removed Itani 00 5ta-gii/_ ,terophylla _________ ca smnuatkix, lica...Carissa grandiflora Natal Plum(~)Codiaeum variegatumn Croton 0 Gardenia taitensis Tiare Gardenia XHibiscus rosa-sinensis Hibiscus .0Impatiens sultani

  4. The Influence of Exposure, Parents, and Linguistic Distance on Young European Learners' Foreign Language Comprehension

    ERIC Educational Resources Information Center

    Lindgren, Eva; Munoz, Carmen

    2013-01-01

    The project Early Language Learning in Europe (ELLiE) has studied the longitudinal effects of an early foreign language (FL) start in seven European contexts. This article presents a sub-study of ELLiE that investigates the impact of out-of-school factors on learners' listening and reading skills in year four of formal FL instruction. More…

  5. Genipin Enhances Kaposi’s Sarcoma-Associated Herpesvirus Genome Maintenance

    PubMed Central

    Son, Kuwon; Park, Gyu Hwan; Jung, Jong-Wha; Shin, Yu Su; Seo, Taegun; Hyosun Cho; Kang, Hyojeung

    2016-01-01

    Kaposi's sarcoma-associated herpesvirus (KSHV) is a Gammaherpesvirus that causes acute infection and establishes life-long latency. KSHV causes several human cancers, including Kaposi's sarcoma, an acquired immune deficiency syndrome (AIDS)-related form of non-Hodgkin lymphoma. Genipin, an aglycone derived from geniposide found in Gardenia jasminoides, is known to be an excellent natural cross-linker, strong apoptosis inducer, and antiviral agent. Although evidence suggests antiviral activity of genipin in several in vitro viral infection systems, no inhibitory effect of genipin on KSHV infection has been reported. Thus, our aim was to determine, using the iSLK-BAC16 KSHV infection system, whether genipin has inhibitory effects on KSHV infection. For this purpose, we evaluated biological effects of genipin on KSHV infection and finally determined the underlying mechanisms responsible for the bioactive effects of genipin. A cytotoxicity assay revealed that genipin caused 50% cytotoxicity at 49.5 μM in iSLK-puro (KSHV-negative) cells and at 72.5 μM in iSLK-BAC16 (KSHV-positive) cells. Caspase 3/7 activities were slightly suppressed by genipin treatment in iSLK-BAC16 cells while significantly induced in iSLK-puro cells. Production of the KSHV latency-associated nuclear antigen (LANA), but not that of the R-transactivator (RTA) protein, was significantly induced by genipin treatment at lower concentration. Consistent with the LANA upregulation, KSHV LANA transcripts, but not RTA transcripts, were expressed at a higher level. Furthermore, KSHV intracellular copy numbers were slightly increased at lower concentration of genipin, while KSHV extracellular copy numbers were significantly increased at higher concentration of genipin. Interestingly, genipin treatment at a lower concentration did induce the expression of DNA (cytosine-5)-methyltransferase 1 (DNMT1); however, a co-immunoprecipitation assay showed that the DNMT1 and LANA induced by genipin did not co

  6. Screening of antibacterial potentials of some medicinal plants from Melghat forest in India.

    PubMed

    Tambekar, D H; Khante, B S; Chandak, B R; Titare, A S; Boralkar, S S; Aghadte, S N

    2009-05-07

    Cyperus rotundus, Caesalpinia bonducella, Tinospora cordifolia, Gardenia gummifera, Ailanthus excelsa, Acacia arabica, Embelia ribes and Ventilago maderspatana from Melghat forest were screened for their antibacterial potential against Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Proteus vulgaris, Salmonella typhi, Shigella flexneri, Salmonella paratyphi, Salmonella typhimurium, Pseudomonas aeruginosa, Enterobacter aerogenes by disc diffusion method. Out of these medicinal plants Caesalpinia bonducella, Gardenia gummifera and Acacia arabica showed remarkable antibacterial potential. The phytochemical analysis had showed the presence of Cardiac glycosides in all extracts (aqueous, acetone, ethanol and methanol) of Acacia arabica, Gardenia gummifera and ethanol, methanol extracts of Caesalpinia bonducella. Flavonoids were present in Gardenia gummifera, Ailanthus excelsa and acetone, methanol extracts of Acacia Arabica. Tannins and phenolic were present in Cyperus rotundus, Embelia ribes, and organic extracts of Ventilago maderspatana.

  7. 76 FR 34136 - Qualification of Drivers; Exemption Applications; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-10

    ... in a CMV. James A. Ellis Mr. Ellis, 54, has had cataract in his left eye since birth. The best.... Stromwall, 51, has aphakia and amblyopia in his left eye due to cataract surgery at age 5. The...

  8. 76 FR 4724 - Catawba Sox, LLC Formerly Known as Catawba Sox, Inc. Including Workers Whose Unemployment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-26

    ... Whose Unemployment Insurance UI) Wages Are Paid Through Ellis Hosiery Mill, LLC, Newton, NC; Amended... unemployment insurance (UI) tax account under the name Ellis Hosiery Mill, LLC, formerly known as Catawba Sox... workers whose unemployment insurance (UI) wages are paid through Ellis Hosiery Mill, LLC, Newton,...

  9. 76 FR 52291 - Proposed Amendment of Class E Airspace; Jacksonville, NC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-22

    ... Procedures have been developed at Albert J Ellis Airport. This action would enhance the safety and airspace... instrument approach procedures developed at Albert J Ellis Airport, Jacksonville, NC, and for continued... at Albert J Ellis Airport, Jacksonville, NC. Lists of Subjects in 14 CFR Part 71...

  10. 77 FR 12992 - Amendment of Class E Airspace; Jacksonville, NC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-05

    ... amends Class E airspace at Albert J. Ellis Airport, Jacksonville, NC, by updating the geographic... Navigation Services to update the geographic coordinates of Albert J. Ellis Airport, Jacksonville, NC. This... the surface, at Albert J. Ellis Airport, Jacksonville, NC. The geographic coordinates of the...

  11. Growth in Emotional Intelligence. Psychotherapy with a Learning Disabled Girl

    ERIC Educational Resources Information Center

    Chantrell, Sue

    2009-01-01

    This paper describes the once-weekly psychoanalytic psychotherapy of a girl, called Ellie, aged eight at the start of her treatment. Ellie had a learning disability and displayed difficult behaviour at school and at home. In her therapy, Ellie grew in emotional intelligence, more in touch with and able to express her feelings. Her behaviour…

  12. Compounds from the roots of Jasminum sambac.

    PubMed

    Zeng, Lin-Hong; Hu, Min; Yan, Yong-Ming; Lu, Qing; Cheng, Yong-Xian

    2012-01-01

    Four new compounds (+)-jasminoids A, B, C, and D, together with seven known compounds, were isolated from the roots of Jasminum sambac. Their structures were identified using spectroscopic methods. This study provides a better understanding to the chemical composition of J. sambac roots that have been thought to be one ingredient of an ancient prescription 'Ma-Fei-San'.

  13. Domiciliation trend of Panstrongylus rufotuberculatus in Colombia.

    PubMed

    Wolff, Marta; Castillo, Diana

    2002-04-01

    The present paper presents evidence of the domiciliation of Panstrongylus rufotuberculatus in La Gardenia, Colombia through the collection of 2 unhatched eggs, 81 nymphs and 10 adults (4 males and 6 females), from 2 rural houses. The transmission risk indicators of Trypanosoma cruzi by P. rufotuberculatus in La Gardenia, were: domiciliary infestation 7.5%, density 2.35, colonization 66.6%, overcrowding 31.33, natural infection 4.6%, and relative infection 2.5%. These results and findings in Peru and Argentina, show that P. rufotuberculatus has a potential success in domiciliation and could some day become an alternate vector of American trypanosomiasis.

  14. Base Exterior Architecture Plan

    DTIC Science & Technology

    1989-02-01

    Sedlum confusum 00 2-112 Gal Hibiscus rosa-silensis 1 Gal Murraya paniculata u ,-s to be removed 1181 x 00 A.%~ ~ Of\\o SLNnkI -V- -V. Cof 1368 136 1...Carissa grandiflora Natal Plum Codlasumn variegatumn Croton 0Gardenia taitensis Tiare Gardenia DxHibiscus rosa-sinensis Hibiscus 0Impatiens sultani... Hibiscus 1 Gal. or 2-1/2 Gal. Impatiens 1 Gal. Ixora 1 Gal. no Texas Privet 5 Gal. Mock Orange 1 Gal. Oleander 1 Gal. Tobira 2-1/2 to 5 Gal. Bird of Paradise

  15. 40 CFR 81.252 - Northwest Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., Cheyenne County, Decatur County, Ellis County, Gove County, Graham County, Logan County, Ness County..., Sheridan County, Sherman County, Smith County, Thomas County, Trego County, Wallace County....

  16. 40 CFR 81.252 - Northwest Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., Cheyenne County, Decatur County, Ellis County, Gove County, Graham County, Logan County, Ness County..., Sheridan County, Sherman County, Smith County, Thomas County, Trego County, Wallace County....

  17. 40 CFR 81.252 - Northwest Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., Cheyenne County, Decatur County, Ellis County, Gove County, Graham County, Logan County, Ness County..., Sheridan County, Sherman County, Smith County, Thomas County, Trego County, Wallace County....

  18. 40 CFR 81.252 - Northwest Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., Cheyenne County, Decatur County, Ellis County, Gove County, Graham County, Logan County, Ness County..., Sheridan County, Sherman County, Smith County, Thomas County, Trego County, Wallace County....

  19. Zinc Selenide Photoelectrodes. Efficient Radiative Recombination in a Stable Photoelectrochemical Cell.

    DTIC Science & Technology

    1984-05-25

    Patricia M. Smiley, Richard N. Biagioni , and Arthur B. Ellis Prepared for Publication in Journal of the Electrochemical Society Department of Chemistry...ORG. REPORT NUMBER 7. AUT’O,O@() 8. CONTRACT OR GRANT NUMBER(oj Patricia M. Smiley, Richard N. Biagioni , and Arthur B. Ellis NOO0l4-78-’C-O633 P...M. Olken, R. N. Biagioni , and A. B. Ellis, Inorg. Chem., 22, 000 (1983). 14. M. K. Carpenter, H. H. Streckert, and A. B. Ellis, J. Solid State Chem

  20. 40 CFR 81.252 - Northwest Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., Cheyenne County, Decatur County, Ellis County, Gove County, Graham County, Logan County, Ness County..., Sheridan County, Sherman County, Smith County, Thomas County, Trego County, Wallace County....

  1. 78 FR 26679 - Kansas Disaster #KS-00073

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-07

    ..., Dickinson, Ellis, Franklin, Harper, Harvey, Hodgeman, Kingman, Marion, Mcpherson, Ness, Osage, Osborne, Pawnee, Phillips, Pratt, Rice, Rooks, Rush, Russell, Smith, Stafford. The Interest Rates are: Percent...

  2. Potential application for genipin-modified gelatin in leather processing

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Genipin is an iridoid compound extracted from gardenia fruits. Because of its low cytotoxicity, genipin can be used to replace both glutaraldehyde and formaldehyde as a crosslinking reagent. In recent years, research into the utilization of genipin for the modification of gelatin, particularly in ...

  3. Evaluation of photo-mutagenicity and photo-cytotoxicity of food coloring agents.

    PubMed

    Arimoto-Kobayashi, Sakae; Machida, Masaki; Okamoto, Keinosuke; Yamaguchi, Akie

    2005-05-01

    Pigments extracted from natural products are widely used for food coloration in Japan. An investigation concerning the photo-mutagenicity and photo-carcinogenicity of frequently used colorants in Japan was performed. Colorants examined were from Laccifer lacca (lac-color), Coccus cacti (cochineal-color), Carthamus tinctorius (carthamus yellow), Gardenia augusta (gardenia yellow and gardenia blue), Monascus anka and Monascus purpureus (monascus red), the skin of Vitis vinifera and Vitis labrusca (grape-skin color), Tamarindus indica (tamarind brown) and Beta vulgaris (beet red). No significant increase in bacterial mutation was found when Salmonella typhimurium TA98, TA100 and TA102 were simultaneously treated with colorants and subjected to UVA irradiation for 30 min. When colorant solutions were subjected to UVA irradiation for 4 h, irradiated solutions containing lac-color became slightly mutagenic toward S.typhimurium TA98 without metabolic activation. A decrease in cell survival resulted when WTK-1 cells were subjected to UVA irradiation for 60 min in the presence of purpurin at 1 mg/ml. Delayed cytotoxicity was also observed following 24 h incubation in fresh medium of samples that were subjected to UVA irradiation for 60 min in the presence of colorant (carthamus yellow, grape-skin color, gardenia blue, cochineal-color, monascus red or purpurin).

  4. Potential application for genipin-modified gelatin in leather processing

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Genipin is a non-toxic iridoid compound, extracted from the gardenia fruits, and, because of its low cytoxicity, is replacing both glutaraldehyde and formaldehyde as a crosslinking reagent. In prior research we had shown the potential of chemical (glutaraldehyde) and enzyme (transglutaminase) modif...

  5. Online Argument between Israeli Jews and Palestinians

    ERIC Educational Resources Information Center

    Ellis, Donald G.; Maoz, Ifat

    2007-01-01

    Previous research with face-to-face groups found that majority-minority theory was a better predictor of argument patterns between Israelis and Palestinians than cultural codes theory (D. G. Ellis & I. Maoz, 2002; I. Maoz & D. G. Ellis, 2001). But, because of the difficulties of organizing face-to-face contacts between Israelis and Palestinians…

  6. Cantonese versus Canadian Evaluation of Directive and Non-Directive Therapy.

    ERIC Educational Resources Information Center

    Waxer, Peter H.

    1989-01-01

    Examined differences between Canadian and Cantonese university students who read transcripts of Carl Rogers and Albert Ellis counseling sessions and rated these counselors on directiveness, forcefulness, repetitiveness, sensitivity, politeness, and willingness to see either Ellis or Rogers. Found Canadians more willing to see Rogers than Chinese…

  7. Subject Characteristics and Preferences for Different Approaches to Psychotherapy: A Multivariate Study

    ERIC Educational Resources Information Center

    Helweg, Gregory C.; Gaines, Lawrence S.

    1977-01-01

    Selected personality variables, sex, age, interpersonal values, and educational level, were examined as antecedents to preferences for a nondirective (Carl Rogers) or directive (Albert Ellis) therapist. Individuals who preferred the Ellis presentation proved to more dogmatic and externalized than individuals preferring the Rogers presentation.…

  8. The Anthropocene Biosphere: Supporting 'Open Interdisciplinarity' through Blogging.

    PubMed

    Trachtenberg, Zev M; Burns, Thomas J; de Beurs, Kirsten; Ellis, Stephen E; Gates, Kiza K; Hoagland, Bruce W; Kelly, Jeffrey F; Neeson, Thomas M; Randall, Asa R; Schlupp, Ingo; Soppelsa, Peter S; Soreghan, Gerilyn S; Zeigler, James J

    2017-01-01

    This paper describes a process of 'open' interdisciplinary scholarship. Researchers from across the University of Oklahoma blogged about a recent paper by ecologist Erle Ellis, and met in person to discuss posts. They then hosted Ellis for a seminar on questions that emerged, and for a public panel discussion.

  9. Symposium and Workshop Support in Molecular Biology and Biotechnology (5th) Held in University Park, Pennsylvania on February 5, 1986 and July 30-August 1, 1986.

    DTIC Science & Technology

    1987-04-29

    Derived Hepatitis B Vaccine --a Prototype for Future Vaccines" by Ronald W. Ellis of Merck; "The Application of Nuclear Magnetic Resonance Imaging and...Recombinant-Derived Hepatitis B Vaccine - A Prototype for Future Vaccines RONALD W. ELLIS 1:30-2:15 pm Merck The Application of Nuclear Magnetic Resonance

  10. Using Army National Guard Combat Battalions for Peace Operations: A Viable Alternative for the Future.

    DTIC Science & Technology

    2007-11-02

    59Michael J. Hardesty and Jason D. Ellis, Training for Peace Operations: The Army Adapts to the Post-Cold War World, (Washington DC: US Institute of Peace...Component Capability and Credibility. Alexandria VA: Institute for Defense Analysis, 1996. Hardesty , Michael J. and Jason D. Ellis, Training for Peace

  11. News Flash--Hume Still Dead.

    ERIC Educational Resources Information Center

    Eubank, Lynn; Gregg, Kevin R.

    2002-01-01

    In response to Ellis (2002), which resurrects the notion that language acquisition consists of frequency-based abstraction of regularities from input, this article suggests Ellis ignores fundamental and well-known problems, including the poverty of the stimulus, cases of instantaneous acquisition, and evidence for innate knowledge. (Author/VWL)

  12. The Rational-Emotive Approach: A Critique

    ERIC Educational Resources Information Center

    Morris, G. Barry

    1976-01-01

    The critique of Rational-Emotive Therapy aims criticism at Ellis' concept of irrationality, analysis of human behavior and therapeutic techniques. Ellis suggests that his critic's claims lack the support of experimental evidence. He further suggests that an "existential" bias pervades which differs from his own brand of…

  13. Finding a Balance: A Narrative Inquiry into Motherhood and the Doctoral Process

    ERIC Educational Resources Information Center

    Eisenbach, Brooke

    2013-01-01

    Carolyn Ellis states, "autoethnography shows struggle, passion, embodied life, and the collaborative creation of sense-making... [it] wants the reader to care, to feel, to empathize, and to do something, to act" (Ellis & Bochner, 2006, p. 433). This autoethnography describes one new mother's struggles to complete her doctoral program of study…

  14. Words, Hemispheres, and Processing Mechanisms: A Response to Marsolek and Deason (2007)

    ERIC Educational Resources Information Center

    Ellis, Andrew W.; Ansorge, Lydia; Lavidor, Michal

    2007-01-01

    Ellis, Ansorge and Lavidor (2007) [Ellis, A.W., Ansorge, L., & Lavidor, M. (2007). Words, hemispheres, and dissociable subsystems: The effects of exposure duration, case alternation, priming and continuity of form on word recognition in the left and right visual fields. "Brain and Language," 103, 292-303.] presented three experiments investigating…

  15. Measuring Implicit and Explicit Linguistic Knowledge: What Can Heritage Language Learners Contribute?

    ERIC Educational Resources Information Center

    Bowles, Melissa A.

    2011-01-01

    Although claims about explicit and implicit language knowledge are central to many debates in SLA, little research has been dedicated to measuring the two knowledge types (R. Ellis, 2004, 2005). The purpose of this study was to validate the use of the battery of tests reported in Ellis (2005) to measure implicit and explicit language knowledge.…

  16. Structural, Material, and Geotechnical Solutions to Levee and Floodwall Construction and Retrofitting - Physical Modeling

    DTIC Science & Technology

    2012-12-01

    Physical Modeling G eo te ch n ic al a n d S tr u ct u re s La b or at or y Wipawi Vanadit-Ellis, Eric W. Smith , Landris T. Lee, and Jared S. Case...Solutions to Levee and Floodwall Construction and Retrofitting – Physical Modeling Wipawi Vanadit-Ellis, Eric W. Smith , and Landris T. Lee...Manager for Water Resources Infrastructure. The Project Leader was Wipawi Vanadit-Ellis, assisted by Eric W. Smith , and Landris T. Lee, all of the

  17. 2. GENERAL VIEW LOOKING EAST SHOWING SOUTH SIDE OF BRIDGE. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. GENERAL VIEW LOOKING EAST SHOWING SOUTH SIDE OF BRIDGE. SHALLOW ARCH ON EXTREME RIGHT SPANS ELLIS ST. - Sudbury River Aqueduct, Echo Bridge, Spanning Charles River at Upper Newton Falls, Newton, Middlesex County, MA

  18. A Web Service Implementation for Large-Scale Automation, Visualization and Real-Time Program Awareness via Lexical Link Analysis

    DTIC Science & Technology

    2011-04-30

    nrfpfqflk obpb^ o `e moldo^j do^ar^qb p`elli lc _rpfkbpp C mr_if` mlif`v k^s^i mlpqdo^ar^qb p`elli bu`bomq colj qeb mêçÅÉÉÇáåÖë çÑ íÜÉ bfdeqe...kkr^i ^`nrfpfqflk obpb^ o `e pvjmlpfrj tbakbpa^v pbppflkp slirjb f Disclaimer: The views represented in this report are those of the authors and do not...nrfpfqflk obpb^ o `e moldo^j do^ar^qb p`elli lc _rpfkbpp C mr_if` mlif`v k^s^i mlpqdo^ar^qb p`elli The research

  19. A Model for Determining Optimal Governance Structure in DoD Acquisition Projects in a Performance-Based Environment

    DTIC Science & Technology

    2010-04-30

    Åèìáëáíáçå=oÉëÉ~êÅÜ=mêçÖê~ã= do^ar^qb= p `elli=lc=_rpfkbpp=C=mr_if`=mlif`v= k^s^i=mlpqdo^ar^qb= p `elli= Approved for public release, distribution...Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 = ^Åèìáëáíáçå=oÉëÉ~êÅÜ=mêçÖê~ã= do^ar^qb= p `elli=lc=_rpfkbpp=C=mr_if`=mlif`v= k^s^i=mlpqdo^ar...qb= p `elli= The research presented at the symposium was supported by the Acquisition Chair of the Graduate

  20. Personal Change and Intervention Style

    ERIC Educational Resources Information Center

    Andrews, John D. W.

    1977-01-01

    Presents a theory of personal change and analyzes growth-producing interventions using examples from the film, "Three Approaches to Psychotherapy". Compares the styles of Carl Rogers, Frttz Perls, and Albert Ellis to illustrate the theory. (Editor/RK)

  1. 77 FR 40945 - Qualification of Drivers; Exemption Applications; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-11

    ...) Tony K. Ellis (IN) Jerry L. Gibson (FL) Rici W. Giesseman (OH) George R. House (MO) Michael A. Jabro (MI) Michael G. Martin (CT) Michael M. Martinez (NM) Robert L. McClain (MI) Daniel E. Miller...

  2. A Guide to the Changing Court Rulings on Union Security in the Public Sector: A Union Perspective.

    ERIC Educational Resources Information Center

    Darko, Richard J.; Knapp, Janet C.

    1985-01-01

    The Supreme Court in "Ellis vs. Brotherhood of Railway, Airline and Steamship Clerks" has provided a systematic process for determining what constitutes union expenses properly charged to objecting nonmembers. (MLF)

  3. Interactions between a group of Golden Eagles and a herd of North American elk

    USGS Publications Warehouse

    O'Connell, Matt P.; Kochert, Michael N.

    2013-01-01

    Raptors are generally considered solitary predators (Schoener 1969), but occasionally they interact socially (Brown and Amadon 1968). Certain raptor species (e.g., Swallow-tailed Kites [Elanoides forficatus] and Swainson's Hawks [Buteo swainsoni]) concentrate in aggregations in response to localized, abundant food sources (Ellis et al. 1993). Many raptor species engage in group hunting (Ellis et al. 1993), and social foraging is a routine strategy for some species (e.g., Harris's Hawks [Parabuteo unicinctus]; Bednarz 1988, Ellis et al. 1993]. Raptors generally engage in group hunting to pursue elusive or large prey (Ellis et al. 1993). Occasionally individuals of conspecific raptors engage in play as a group sometimes involving chases of prey species (Palmer 1988). In this letter, we report interactions between a large group of Golden Eagles and a herd of adult and juvenile Rocky Mountain elk (Cervus canadensis nelsoni) in late autumn.

  4. Congenital heart disease

    MedlinePlus

    ... defect - heartbeat Patent ductus arteriosis (PDA) - series References Fraser CD, Carberry KE. Congenital heart disease. In: Townsend ... ASD) Coarctation of the aorta Ellis-van Creveld syndrome Fetal alcohol syndrome Hypoplastic left heart syndrome Marfan ...

  5. Flight restraint

    USGS Publications Warehouse

    Ellis, D.H.; Dein, F.J.; Ellis, D.H.; Gee, G.F.; Mirande, C.M.

    1996-01-01

    Many techniques are available for pre ve n ting escape of captive cranes. These include tenotomy, tenectomy, wing clipping, confinement under nets, amputation, brailing, and vane trimming (Ellis and Dein 1991). The advantages and limitations of each technique are presented.

  6. 76 FR 79196 - Gluten in Drug Products; Request for Information and Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-21

    .... Green, ``Innate and Adaptive Immunity: The Yin and Yang of Celiac Disease,'' Immunological Reviews, vol...,'' Clinical and Experimental Immunology, vol. 50, pp. 651-660, 1982. 15. Sturgess, R.P., H.J. Ellis, and...

  7. Aeromagnetic maps of the Mazatzal Wilderness and contiguous roadless areas, Gila, Maricopa, and Yavapai counties, Arizona

    USGS Publications Warehouse

    Moss, C.K.; Abrams, G.A.

    1985-01-01

    Studies of the geology, geochemistry (Marsh and others, 1983a, b, Erickson, 1984), mines and prospects (Ellis, 1982), and mineral resource potential (Wrucke and others, 1983) of the Mazatzal Wilderness and contiguous roadless areas have been published elsewhere.

  8. 78 FR 74129 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-10

    ... Francisco, California 94105-1579: 1. John Jung Hun Chang, Wellwish Investment LLC, Ellis Eunrok Chang, all of Garden Grove, California, and Ellen Eunmi Chang, Bellevue, Washington; to retain voting shares...

  9. 75 FR 9477 - Qualification of Drivers; Exemption Applications; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-02

    ... renewable two-year period. They are: Alberto Blanco, Michael B. Canedy, Larry A. Cossin, Charles W. Cox, Gary W. Ellis, Dennis J. Evers, Hector O. Flores, W. Roger Goold, Lee Guse, Steven W. Halsey,...

  10. A Theoretical and Empirical Integration of the Rational-Emotive and Classical Conditioning Theories

    ERIC Educational Resources Information Center

    Russell, Phillip L.; Brandsma, Jeffrey M.

    1974-01-01

    Galvanic skin conductance response, respiration rate and respiration depth values of an experimental and control group were used to test the hypotheses of a Albert Ellis' ABC Theory of psychopathology. (EK)

  11. The Counselor in a Nuclear World: A Rationale for Awareness and Action.

    ERIC Educational Resources Information Center

    Gearhart, Jo Anne

    1984-01-01

    Explores a rationale for counselors' responses to the threat of nuclear annihilation and suggests some action possibilities. Includes a response by Milton Schwebel emphasizing professional roles, and by Albert Ellis emphasizing the dangers of religous zealotism. (Author/JAC)

  12. 78 FR 25462 - Oklahoma; Major Disaster and Related Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... areas and Hazard Mitigation throughout the State. You are further authorized to provide snow assistance... Assistance. Dewey and Ellis Counties for snow assistance under the Public Assistance program for...

  13. California Earthquake Residual Transportation Capability Study.

    DTIC Science & Technology

    1983-12-01

    through vi 0 Gardenia, Signal Hill and Huntington Beach to Newport Beach. The damaged area would extend from the San Fernando Valley to Oceanside. 0...Bernardino. Ocean service could come from San Diego via highway. Survivors in the San Fernando Valley would be supplied by distri- bution trucks that...1971 San Fernando earthquake, then fire, police and other emer- gency services can cope with the major problems. However, a massive earthquake that

  14. Analysis and Modeling of Target Echo and Reverberation: FY15 Annual Report for ONR

    DTIC Science & Technology

    2015-09-30

    during the past year: • Michael A. Ainslie, Dale D. Ellis, and Chris H. Harrison . Low frequency bottom reverberation in a Pekeris waveguide with...Chris H. Harrison . Towards benchmarks of low frequency reverberation level in a Pekeris waveguide: Insight from analytical solutions. J. Acoust...USA, 23–27 May 2011. [AEH15] Michael A. Ainslie, Dale D. Ellis, and Chris H. Harrison . Low frequency bottom reverberation in a Pekeris waveguide

  15. Theory and Algorithms for Global/Local Design Optimization

    DTIC Science & Technology

    2005-09-29

    Sioson, C. Vasquez -Robinet, M. Shukla, D. Kumar, M. Ellis, L. S. Heath, N. Ramakrishnan, B. Chevone, L. T. Watson, L. vanZyl, U. Egertsdotter, R. R...process for eukaryotic cell cycle models with a modeling support environment", in Proc. 2003 Winter Simulation Conf., S. Chick, P. J. Sanchez , D. Ferrin...Watkinson, C. Vasquez -Robinet, M. Ellis, M. Shukla, D. Kumar, N. Ramakrishnan, L. S. Heath, R. Grene, B. I. Chevone, K. Kafadar, and L. T. Watson

  16. Mathematical Modeling to Reduce the Cost of Complex System Testing: Characterizing Test Coverage to Assess and Improve Information Return

    DTIC Science & Technology

    2011-09-21

    Rough sailing: The case of the lame ship. In Proceedings of the Seventh International Conference on Engineering of Computer Based Systems ( EBCS 2000...Åèìáëáíáçå=oÉëÉ~êÅÜ=mêçÖê~ã= do^ar^qb=p`elli=lc=_rpfkbpp=C=mr_if`=mlif`v= = - 46 - k^s^i=mlpqdo^ar^qb=p`elli= public void addModule(Module m

  17. Coast Guard Proceedings. Volume 68, Number 1, Spring 2011

    DTIC Science & Technology

    2011-01-01

    the Marine Event Permit Program by LCDR Ellis H. Moose 28 Abandoned and Derelict Vessel Removal Understanding the process can ensure success. by LCDR...root cause analysis, · intervention selection, · implementation, · evaluation. Improving the Marine Event Permit Program by LCDR ELLIS H. MOOSE ...the author: LCDR Moose is a graduate of the U.S. Merchant Marine Academy and currently assigned to the U.S. Coast Guard Office of Marine

  18. Homosexuals and U.S. Military Policy: Current Issues

    DTIC Science & Technology

    2005-05-27

    Thomasson v. Perry,51 Chief Judge J. Harvie Wilkinson III stressed Congress’ “plenary control” of the military and the “deference” owed both the...Judge Ellis in Thorne v. U.S. Department of Defense.53 After reviewing the record in eight other administrative separation proceedings where the...presumption that a declared homosexual has a propensity to engage in forbidden conduct was successfully rebutted, Judge Ellis in Thorne held that conduct

  19. Homosexuals and U.S. Military Policy: Current Issues

    DTIC Science & Technology

    2005-02-10

    that he was homosexual. Writing for the nine-member majority in Thomasson v. Perry,51 Chief Judge J. Harvie Wilkinson III stressed Congress...Circuit relied on Thomasson to affirm a ruling by federal District Judge Ellis in Thorne v. U.S. Department of Defense.53 After reviewing the record in...successfully rebutted, Judge Ellis in Thorne held that conduct rather than speech was the target of the “don’t ask, don’t tell” policy. In Richenberg

  20. Another Approach to Counter-Terrorism: Terrorists with Guilty Consciences

    DTIC Science & Technology

    2012-12-01

    2004]). 81 M. Crenshaw, Terrorism: What’s Coming the Mutating Threat, ed. J. O. Ellis III ( Oklahoma : Memorial Institute for the Prevention of...Terrorism: What’s Coming the Mutating Threat. The Organization of Terrorism., edited by Ellis III, J. O. Oklahoma : Memorial Institute for the...University Press, 2007. Shu, Lisa L., Francesca Gino, and Max H. Bazerman. “Dishonest Deed, Clear Conscience: When Cheating Leads to Moral

  1. Archeological Testing Fort Hood: 1994-1995. Volume 2

    DTIC Science & Technology

    1996-10-01

    Dering .3 (" G. Lain Ellis 0 t- Glenn Goodfriend oKarl Kleinbach Patrick L. O’Neill J. Michael QuiJgg Marybeth S . F. Tomka W. Nicholas Trierweiler L=C~ q...James T. Abbott Phil Dering G. Lain Ellis Glenn Goodfriend Karl Kleinbach Gemma Mehalchick Patrick O’Neill J. Michael Quigg Marybeth S . F. Towka and...26 2.4.8 Stampede Group .......................................... 27 2.4.9 S ,ell M ountain Group

  2. Gap Analysis: Rethinking the Conceptual Foundations

    DTIC Science & Technology

    2008-01-30

    k ^s^i= mlpqdo^ar^qb= p`elli= jlkqbobvI=`^ifclokf^= = NPS-GSBPP-08-008 Approved for public release, distribution is...Ira Lewis, Associate Professor Graduate School of Business & Public Policy Reviewed by: ________________________________ Robert N. Beck...ix = = k ^s^i= mlpqdo^ar^qb= p`elli= jlkqbobvI=`^ifclokf^= = NPS-GSBPP-08-008 Approved for public release

  3. Modeling and Analysis of Target Echo and Clutter in Range-Dependent Bistatic Environments: FY13 Annual Report for ONR

    DTIC Science & Technology

    2013-09-30

    13] Michael A. Ainslie, Dale D. Ellis, Jan Ehrlich , Pieter Schippers, Karl-Thomas Hjelmervik, and Mathieu E. G. D. Colin. Echo, reverberation and echo...gebco 08.nc, version 20100927. [HOSH10] Paul C. Hines, John C. Osler, Jeffrey G. E. Scrutton, and Landon J. S. Halloran. Time-of-flight measurements...Acoustics held in Edinburgh, Scotland, UK, 2–6 July 2012. [published] • Michael A. Ainslie, Dale D. Ellis, Jan Ehrlich , Pieter Schippers, Karl-Thomas

  4. Modeling and Analysis of Target Echo and Clutter in Range-Dependent Bistatic Environments: FY12 Annual Report for ONR

    DTIC Science & Technology

    2012-09-30

    reverberation level in a Pekeris waveguide : Insight from analytical solutions. J. Acoust. Soc. Am., 129(5, Pt. 2 of 2):2631, 2011. Abstract 4pUW10...Ellis, and Chris H. Harrison. Low frequency bottom reverberation in a Pekeris waveguide with Lambert’s rule. J. Comp. Acoust., 2013. Submitted...Ellis. Two modeling approaches for reverberation in a shallow water waveguide where the scattering arises from a sub-bottom interface. J. Comp

  5. I Will Never Forget: An Analysis of the POW/MIA (Prisoners of War/Missing in Action) Episode in the War in Southeast Asia.

    DTIC Science & Technology

    1982-05-01

    Purcell, Benjamin H., Col Ett: ueiler, Harry L., SSgL Rander, Donald J., SFC . Flora, Carroll E. Jr., SFC Ray, Johnnie L., Capt Frank, ::artin 3.. SS...Jr., Lt Col Elander, William J., Jr., Maj Brenneman, Richard C., Capt Ellis, Jeffrey T., Capt Bridger, Barry B., Capt Ellis, Leon F., Capt Brodak...j * Guy, Theodore W.., Col Logn, c.., t Hall, George R., It Col Lollar. . Hall, Keith I., 1.:aj Luna , jose I., Capz *: Hanson, Gregg 0., 2t

  6. Rational Emotive Behavioural Therapy: The Evolution of a Revolution

    PubMed Central

    Ellis, Debbie Joffe; Rovira, Montse

    2015-01-01

    Recognized as one of the most influential thinkers and psychologists, Albert Ellis PhD (1913-2007) revolutionized Psychology when he created the first cognitive psychotherapy, Rational Emotive Behavioral Therapy. After he passed away, Dr. Debbie Joffe Ellis continues spreading his legacy around the world. Psychologist, lecturer, writer, trainer, she dedicates her life to disseminate REBT and extend it through different statements, from the social to the educational, from the academic to the clinical. In this interview, she goes through her own history and her husband’s one, bringing us closer to understanding Albert Ellis as the leading figure in his field, and the oneness they experienced through their professional and personal relationship. PMID:27247638

  7. Development of an Item Unique Identification Strategy for the Legacy Components of the US Marine Corps M1A1 Abrams Tank

    DTIC Science & Technology

    2008-12-03

    GEARBOX ASSEMBLY,CW 1015010766691 PAOFF $13,059.00 319 GEARBOX , ACCESSORY DRIVE, TURBINE ENGINE 2835011978325 PAFDD $47,763.00 320 GEARBOX ,ACCESSORY DRIVE...Road, Room 332,Monterey,CA,93943 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/ MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR...ã= do^ar^qb=p`elli=lc=_rpfkbpp=C=mr_if`=mlif`v= = - xii - k^s^i=mlpqdo^ar^qb=p`elli= HB Heavy Barrel HEAT High Explosive, Anti-tank HIBCC Health

  8. B2B Models for DoD Acquisition

    DTIC Science & Technology

    2007-07-30

    ar^qb=p`elli=lc=_rpfkbpp=C=mr_if`=mlif`v - i - k^s^i=mlpqdo^ar^qb=p`elli= Abstract A central vision of B2B e - commerce is that of an electronic...are purchased, pricing mechanisms, the characteristics of the markets, and ownership of marketplace. Keywords: B2B E - Commerce , Internet...interest is in the analysis, design and implementation of computer-based information systems. Specifically, he is interested in B2B and B2C e - commerce

  9. Better Acquisition Management through Alternative Dispute Resolution (ADR) and Other Best Practices for Preventing and Resolving Bid Protests

    DTIC Science & Technology

    2012-01-24

    ESLS ) made cost = = ^Åèìáëáíáçå=oÉëÉ~êÅÜ=mêçÖê~ã= do^ar^qb=p`elli=lc=_rpfkbpp=C=mr_if`=mlif`v - 66 - k^s^i=mlpqdo^ar^qb=p`elli= and availability...Mobility Command (AMC). Regarding cost, the ESLS found that the KC-135 fleet would incur “significant cost increases” between 2001 and 2040, but “no...the ESLS publication, the Air Force planned to wait until 2013 to begin KC-135 replacement. (Gupta, Belasco, Else, & O’Rourke, 2003, pp. 2– 3

  10. Urination and its discontents.

    PubMed

    Weinberg, J

    1994-01-01

    "Urination and Its Discontents" is an attempt to answer why various twentieth-century artists have made works that use or are about urination. Andy Warhol's act of "pissing" onto a canvas in his Oxidation Paintings is related to homosexual "sex clubs," but also to the iconoclasm of Mapplethorpe, Serrano, Duchamp, and Pollock. Freud's idea that civilization began with the renunciation of the "homosexual competition" of urinating on the fire is discussed and compared to Ellis's idealization of the erotics of bodily functions. Weinberg suggests that artists follow Ellis instead of Freud in undermining the boundaries society places on what is clean and dirty and what is sexually permissible.

  11. Transaction Costs from a Program Manager’s Perspective

    DTIC Science & Technology

    2009-09-28

    5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME...AVAILABILITY STATEMENT Approved for public release; distribution unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT This project continues ongoing efforts...êÅÜ=mêçÖê~ã= do^ar^qb=p`elli=lc=_rpfkbpp=C=mr_if`=mlif`v - i - k^s^i=mlpqdo^ar^qb=p`elli= Abstract This project continues ongoing efforts by the

  12. Relation of irrational thinking and the Pessimistic Explanatory Style.

    PubMed

    Ziegler, D J; Hawley, J L

    2001-04-01

    This study investigated the possible relationship between Ellis's construct of irrational thinking and Seligman's construct of explanatory style, with a view toward possibly strengthening the personality theory underlying Rational Emotive Behavior Therapy in particular and cognitive-behavior therapies more generally. In this investigation 180 college students were administered the Survey of Personal Beliefs and the Attributional Style Questionnaire to measure irrational thinking and explanatory style, respectively. Students who scored higher on Pessimistic Explanatory Style also scored higher on Overall Irrational Thinking and on Low Frustration Tolerance than did those who were categorized as having an Optimistic Explanatory Style. This indicates support for Ellis's developing personality theory, especially his theoretical account of depression.

  13. Comparative Thermal Degradation Patterns of Natural Yellow Colorants Used in Foods.

    PubMed

    Giménez, Pedro J; Fernández-López, José A; Angosto, José M; Obón, José M

    2015-12-01

    There is a great interest in natural yellow colorants due to warnings issued about certain yellow food colorings of synthetic origin. However, no comparative studies have been reported of their thermal stability. For this reason, the thermal stabilities of six natural yellow colorants used in foods--lutein, riboflavin, curcumin, ß-carotene, gardenia yellow and Opuntia betaxanthins--were studied in simple solutions over a temperature range 30-90 °C. Spectral properties and visual color were investigated during 6 h of heat treatment. Visual color was monitored from the CIEL*a*b* parameters. The remaining absorbance at maximum wavelength and the total color difference were used to quantify color degradation. The rate of color degradation increased as the temperature rose. The results showed that the thermal degradation of the colorants followed a first-order reaction kinetics. The reaction rate constants and half-life periods were determined as being central to understanding the color degradation kinetics. The temperature-dependent degradation was adequately modeled on the Arrhenius equation. Activation energies ranged from 3.2 kJmol(-1) (lutein) to 43.7 kJmol(-1) (Opuntia betaxanthins). ß-carotene and lutein exhibited high thermal stability, while betaxanthins and riboflavin degraded rapidly as temperature increased. Gardenia yellow and curcumin were in an intermediate position.

  14. Anti-inflammatory activity of Chinese medicinal vine plants.

    PubMed

    Li, Rachel W; David Lin, G; Myers, Stephen P; Leach, David N

    2003-03-01

    Anti-inflammatory activities of ethanol extracts from nine vine plants used in traditional Chinese medicine to treat inflammatory conditions were evaluated against a panel of key enzymes relating to inflammation. The enzymes included cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2), phospholipase A(2) (PLA(2)), 5-lipoxygenase (5-LO) and 12-lipoxygenase (12-LO). The vine plants studied were: the stem of Spatholobus suberectus Dunn, the stem of Trachelospermum jasminoides Lem., the root from Tripterygium wilfordii Hook. f., the stem of Sinomenium acutum Rehder and Wilson, the stem of Piper kadsura (Choisy) Ohwi, the stem of Polygonum multiflorum Thunb., the root and stem from Tinospora sagittata Gagnep., the root of Tinospora sinensis (Lour.) Merrill, and the stem of Clematis chinensis Osbeck. All of the plant extracts showed inhibitory activities against at least one of the enzymes in various percentages depending upon the concentrations. The extract from S. suberectus was found to be active against all enzymes except COX-2. Its IC(50) values were 158, 54, 31 and 35 microg/ml in COX-1, PLA(2), 5-LO and 12-LO assays, respectively. T. jasminoides showed potent inhibitory activities against both COX-1 (IC(50) 35 microg/ml) and PLA(2) (IC(50) 33 microg/ml). The most potent COX-1, COX-2 and 5-LO inhibition was observed in the extract of T. wilfordii with the IC(50) values of 27, 125 and 22 microg/ml, respectively. The findings of this study may partly explain the use of these vine plants in traditional Chinese medicine for the treatment of inflammatory conditions.

  15. Radical Reactions in the Decomposition of Energetic Materials

    DTIC Science & Technology

    2014-10-08

    PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. University of Chicago 5801 South Ellis Avenue Chicago , IL 60637 -5418 ABSTRACT Final Report...Decomposition of Energetic Materials" L. J. Butler, The University of Chicago W911NF1010314, Program Manager James Parker Final  Report  for

  16. The Genomic Evolution of Prostate Cancer

    DTIC Science & Technology

    2014-10-01

    Ph D CONTRACTING ORGANIZATION: University of Chicago REPORT DATE: October 2014 TYPE OF REPORT: Annual...NUMBER University of Chicago , The 5801 S Ellis Ave Chicago IL 60637-5418 9. SPONSORING / MONITORING...Human Tissue Resources Core at the University of Chicago to identify additional cases of coincident ductal and acinar carcinoma with sufficient

  17. Response to Pienemann's Critique of Zhang and Lantolf (2015)

    ERIC Educational Resources Information Center

    Lantolf, James P.; Zhang, Xian

    2015-01-01

    We respond here to Pienemann's critique of our study that appeared earlier this year in the Language Learning Special Issue entitled "Orders and Sequences in the Acquisition of L2 Morphosyntax, 40 Years On" and guest edited by Jan Hulstijn, Rod Ellis, and Søren Eskildsen. Pienemann objected to our claim that the Teachability Hypothesis…

  18. Traversable intra-Universe wormholes and timeholes in General Relativity: two new solutions

    NASA Astrophysics Data System (ADS)

    Smirnov, Alexey L.

    2016-11-01

    Using thin shell formalism we construct two solutions of intra-Universe wormholes. The first model is a cosmological analog of the Aichelburg-Schein timehole, while another one is an intra-Universe form of the Bronnikov-Ellis solution.

  19. Positive Evidence Versus Explicit Rule Presentation and Explicit Negative Feedback: A Computer-Assisted Study

    ERIC Educational Resources Information Center

    Sanz, Cristina; Morgan-Short, Kara

    2004-01-01

    The facilitative role of explicit information in second language acquisition has been supported by a significant body of research (Alanen, 1995; Carroll & Swain, 1993; de Graaff, 1997; DeKeyser, 1995; Ellis, 1993; Robinson, 1996, 1997), but counterevidence is also available (Rosa & ONeill, 1999; VanPatten & Oikkenon, 1996). This experimental study…

  20. Alleviating Communication Apprehension through Rational Emotive Therapy: A Comparative Evaluation.

    ERIC Educational Resources Information Center

    Watson, Arden K.; Dodd, Carley H.

    Albert Ellis's Rational Emotive Therapy (RET), which assumes that a person can change an emotional disturbance by discovering and disputing the irrational ideas giving rise to that emotion, has been used effectively in treating public speaking anxiety. To compare RET with other treatments for communication apprehension, 52 high communication…

  1. The Relationship between Supervisors' Power Bases and Supervisory Styles

    ERIC Educational Resources Information Center

    Tanaka, Hideyuki

    2009-01-01

    Despite its critical role in counselor training, empirical research on clinical supervision is generally limited (Bernard & Goodyear, 2003; Ellis & Ladany, 2007). This is also applied to an area of power dynamics in supervision. This study tested the relationship between the two aspects of power dynamics; namely, supervisors' power bases (i.e.,…

  2. Motivating the Gifted, Talented, Creative. A Meta-Analysis.

    ERIC Educational Resources Information Center

    Shaughnessy, Michael F.

    The main theories of motivation are reviewed in an effort to help teachers discern various tactics and techniques that they can use with gifted, talented, and creative students. Among the theories examined are Ivan Pavlov's respondent conditioning; Albert Ellis's rational-emotive approach; Abraham Maslow's triangular approach to growth and…

  3. Latin America Report

    DTIC Science & Technology

    2007-11-02

    Amaro Cuellar Flor. Ucayali: Atalaya, Dorian Campos Vargas ; Coronel Portillo, Policarpio Ramirez Falcon; Padre Abad, Luis Alvan Freeh. [Text] [Lima EL...Walcott beat Charles Augustin to the post of party chairman. Deputy Chairman is Henry Marquis. 99 Hilary Modeste and Ellis Edward were re-elected

  4. The Fifth Data Release of the Sloan Digital Sky Survey

    DTIC Science & Technology

    2007-10-01

    084 Krakow, Poland. 41 Enrico Fermi Institute, University of Chicago, 5640 South Ellis Avenue, Chicago, IL 60637. 42 Lawrence Berkeley National...18,41 Idit Zehavi,73 Stefano Zibetti,70 and Daniel B. Zucker6,10 Received 2006 October 12; accepted 2007 March 19 1 Fermi National Accelerator

  5. The Effect of Teachers' Written Corrective Feedback (WCF) Types on Intermediate EFL Learners' Writing Performance

    ERIC Educational Resources Information Center

    Aghajanloo, Khadijeh; Mobini, Fariba; Khosravi, Robab

    2016-01-01

    Written Corrective Feedback (WCF) is a controversial topic among theorists and researchers in L2 studies. Ellis, Sheen, Murakami, and Takashima (2008) identify two dominant dichotomies in this regard, that is focused vs. unfocused WCF and direct vs. indirect WCF. This study considered both dichotomies in a matrix format, resulted in the…

  6. The Experience of Daily Hassles, Cardiovascular Reactivity and Adolescent Risk Taking and Self-Esteem

    ERIC Educational Resources Information Center

    Vermeersch, Hans; T'Sjoen, Guy; Kaufman, Jean-Marc; Vincke, John; Bracke, Piet

    2010-01-01

    Based on Boyce and Ellis's model on "context" and "biological sensitivity to the context", this article analyzes the interaction between the experience of daily hassles and experimentally induced cardiovascular reactivity as an indicator of stress reactivity, in explaining risk taking and self-esteem. This study found, in a…

  7. Prevalence of Traumatic Dental Injuries in Patients Attending University of Alberta Emergency Clinic

    PubMed Central

    Alkhadra, Thamer; Preshing, William; El-Bialy, Tarek

    2016-01-01

    Objectives: This study evaluated the prevalence of dental trauma for patients attending the emergency dental clinic at the University of Alberta Hospital between 2006-2009. Patients’ examination and treatment charts were reviewed. Methods: Total number of patients’ charts was 1893.The prevalence of different types of trauma was 6.4 % of the total cases (117 patients). Trauma cases were identified according to Ellis classification and as modified by Holland et al., 1988. Results: Logistic statistical model showed that 21.7% were Ellis class I trauma, 16.7% were Ellis class II trauma, and 6.7% were Ellis class III. In addition, 11.7 % presented with avulsion, 7.5 % presented with dentoalveolar fracture and 7.5% presented with sublaxation. Also, 17.55 % presented with tooth displacement within the alveolar bone, 3.3 % presented with crown fracture with no pulp involvement, 4.16 % presented with crown fracture with pulp involvement and 3.3 % presented with root fracture. In conclusion, the general prevalence of dentoalveolar trauma in patients attending the emergency clinic at the University of Alberta is less than other reported percentages in Canada or other countries. PMID:27398104

  8. Race, Reification, and Responsibility.

    ERIC Educational Resources Information Center

    Cancro, Robert

    Noting that many of the attacks on individual scientists as well as some of the attacks on the field of behavior genetics are more than intemperate--they are non-rational--the author discusses his experience as a signatory to a document drawn up by Ellis B. Page during the winter of 1971-1972. The intent of this controversial document was to…

  9. Generalizing: The Core of Algebraic Thinking

    ERIC Educational Resources Information Center

    Kinach, Barbara M.

    2014-01-01

    Generalizing--along with conjecturing, representing, justifying, and refuting--are forms of mathematical reasoning important in all branches of mathematics (Lannin, Ellis, and Elliott 2011). Increasingly, however, generalizing is recognized as the essence of thinking in algebra (Mason, Graham, and Johnston-Wilder 2010; Kaput, Carraher, and Blanton…

  10. 75 FR 82275 - Changes in Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-30

    ... under the criteria of section 3(f) of Executive Order 12866 of September 30, 1993, Regulatory Planning..., 10th Floor, 400 Stewart Avenue, Las Vegas, NV 89101. New York: Niagara Town of Cambria (07- October 18, 2007; The Honorable Wright H. January 24, 2008 360499 02-0919P). October 25, 2007; Ellis, Cambria...

  11. Developing Researcherly Dispositions in an Initial Teacher Education Context: Successes and Dilemmas

    ERIC Educational Resources Information Center

    Roche, Mary

    2014-01-01

    Douglas and Ellis (2011, p. 175) suggest that institutionally universities and schools are required to work with different conceptual tool-kits. Seeking to minimise the potential standoff between academic and practitioner knowledge, and, therefore, to enhance the learning of student teachers, means, they suggest, rethinking both the social…

  12. Teaching Second Language Acquisition Courses: Views from New Faculty

    ERIC Educational Resources Information Center

    Gorsuch, Greta J.; Beglar, David

    2004-01-01

    Second language acquisition (SLA) courses are a perennial feature of graduate level teacher preparation programs in Applied Linguistics and TESOL. While there has been recent interest in exploring the interfaces of second language acquisition research and classroom teaching (Ellis, 1997), the teaching of SLA courses at the university level is…

  13. Sensor Placement Design for Object Pose Determination with Three Light- Stripe Range Finders

    DTIC Science & Technology

    1994-05-10

    uncertainties in polyhedral object recognition. IEEE Transactions on Robotics and Automation, 7(3):361-371, June 1991. [6] R. E. Ellis. Planning...cell with multi-sensor capabilities. IEEE Transactions on Robotics and Automation, 5(6):765- 783, December 1989. [151 K. Ikeuchi and T. Kanade. Modeling

  14. 75 FR 8109 - National Register of Historic Places; Weekly Listing of Historic Properties

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-23

    ...., Jefferson, 09000973, LISTED, 12/02/09 NEW YORK Kings County Kol Israel Synagogue, 603 St. John's Place... County Attucks School, 346 S. 4th, Vinita, 09000974, LISTED, 12/03/09 Ellis County Ingle Brothers...., Cushing, 09000979, LISTED, 12/ 03/09 TEXAS Collin County Allen Water Station, N. of Exchange Pkwy...

  15. Gifted Programs.

    ERIC Educational Resources Information Center

    Roeper Review, 1979

    1979-01-01

    Descriptions of four gifted programs are offered in articles titled "Career Education for Gifted Students in Illinois" (J. Ellis and B. Ford); "Interage Program for Critical Thinking" (H. Masterson); "Talcott Mountain Science Center" (D. LaSalle); and "Project L.O.G.I.C.--Nurturing the Mathematically Gifted" (W. Foley and B. Spack). (SBH)

  16. Teachers' and Learners' Reactions to a Task-Based EFL Course in Thailand

    ERIC Educational Resources Information Center

    McDonough, Kim; Chaikitmongkol, Wanpen

    2007-01-01

    Although many studies have described the L2 learning opportunities created by individual tasks, considerably less research has investigated task-based syllabi and courses (Bruton, 2002; Candlin, 2001; Ellis, 2003; Skehan, 2003). This case study investigated teachers' and learners' reactions to a task-based EFL course at a Thai university. A team…

  17. Evolution of a Computer-Based Testing Laboratory

    ERIC Educational Resources Information Center

    Moskal, Patrick; Caldwell, Richard; Ellis, Taylor

    2009-01-01

    In 2003, faced with increasing growth in technology-based and large-enrollment courses, the College of Business Administration at the University of Central Florida opened a computer-based testing lab to facilitate administration of course examinations. Patrick Moskal, Richard Caldwell, and Taylor Ellis describe the development and evolution of the…

  18. Impact of Consciousness-Raising Activities on Young English Language Learners' Grammar Performance

    ERIC Educational Resources Information Center

    Fatemipour, Hamidreza; Hemmati, Shiva

    2015-01-01

    Grammar Consciousness-Raising (GCR) is an approach to teaching of grammar which learners instead of being taught the given rules, experience language data. The data challenge them to rethink, restructure their existing mental grammar and construct an explicit rule to describe the grammatical feature which the data illustrate (Ellis, 2002). And…

  19. A Voice from the Past: Catharine Beecher's Response to Simone de Beauvoir

    ERIC Educational Resources Information Center

    Murphy, Madonna M.

    2002-01-01

    Charlesetta Ellis, President of the Midwest Philosophy of Education Society (2002-2004) gave the Presidential Address at the 2002 MPES Annual Meeting, November 8, 2002 at Chicago State University regarding the important contributions made by Simone de Beauvoir to education and especially the education of women. This paper is a response to the…

  20. The Long Run

    ERIC Educational Resources Information Center

    Donnelly, Laura

    2007-01-01

    This article profiles six educators who have taught for as long as two generations. These educators are the following: (1) Hazel Wilson--teaching 47 years; (2) Agnes Zeiger--teaching 61 years; Rose Gilbert--teaching 51 years; (4) Ellie Johnson--teaching 52 years; (5) Roy Clare--teaching 48 years; and (6) Carrie Hansen--54 years in education. These…

  1. Effects of Host Resistance and Shading Density on the Disease Severity of Hydrangea Leaf Spot

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Leaf spot, caused by Cercospora hydrangeae Ellis & Everh., is a common disease of bigleaf hydrangea (Hydrangea macrophylla) in ornamental nurseries and gardens. Experiments were conducted to determine the effects of cultivars and shading density on the disease severity. Two year-old plants of six bi...

  2. The Relationship between Teachers' Beliefs of Grammar Instruction and Classroom Practices in the Saudi Context

    ERIC Educational Resources Information Center

    Alghanmi, Bayan; Shukri, Nadia

    2016-01-01

    Teacher cognition (Borg, 2015) of grammar instruction is a relatively new phenomenon that has yet to be explored in the Saudi context. While many studies have focused on the teaching of grammar in general (Ellis, 2006; Corzo, 2013; Braine, 2014), further research needs to be done - particularly when it comes to understanding teachers' beliefs of…

  3. Study of Family Memoir and Ideologies of Gender: Application to the Intersection of the Creative and the Scholarly in the Writing Classroom

    ERIC Educational Resources Information Center

    Williams, Elly

    2006-01-01

    Elly Williams is an adjunct instructor at Johns Hopkins where she received her M.A. in writing. She is a faculty member for the Sewanee Young Writers' Conference, and the author of the novel "This Never Happened." The article she presents here is divided into three parts: (1) Tales of a Grandmother's Commonplace Memoir; (2) Assignment:…

  4. 6. VIEW OF BRIDGE COMMEMORATIVE PLAQUE WHICH STATES '1908, J. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. VIEW OF BRIDGE COMMEMORATIVE PLAQUE WHICH STATES '1908, J. H. CROOKS, ED. ELLIS, A. S. LELAND, COMMISSIONERS. L. E. BRELSFORD, AUDITOR. L. WEST, SURVEYOR. - B. C. GERWICK, DESIGNER. F. E. WITHCOTT, ENG. ON CONST. C. A. WARNER, CONTRACTOR.' - First Street Reinforced Concrete Bridge, Spanning Moxahala Creek at First Street (CR 7), Roseville, Muskingum County, OH

  5. Effects of Pretask Modeling on Attention to Form and Question Development

    ERIC Educational Resources Information Center

    Kim, YouJin

    2013-01-01

    Over the last two decades, a growing body of research has shown positive impacts for task planning in task-based instruction (e.g., Ellis, 2005; Foster & Skehan, 1996). However, what learners plan during pretask planning, and whether any specific planning strategies are more beneficial in encouraging learners to attend to linguistic forms and…

  6. Educational Considerations for the Learning Disabled Adolescent: Selected Papers.

    ERIC Educational Resources Information Center

    Ensminger, E. Eugene, Ed.; Smiley, Lydia R., Ed.

    Presented are 11 papers from a seminar entitled Secondary Programs for the Adolescent with Learning Disabilities. Entries include the following titles and authors: "Parent-Adolescent Interaction" (D. Ellis); "The Development of the Adolescent Self-Concept" (M. Smith); "The Self-Concept of the Learning Disabled Adolescent" (B. Lockett); "Brief…

  7. First report of powdery mildew caused by Podosphaera leucotricha on Callery pear in North America

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Podosphaera leucotricha (Ellis & Everh.) E.S. Salmon (Ascomycetes, Erysiphales) is the etiological agent of a powdery mildew disease that occurs on rosaceous plants, primarily Malus and Pyrus. This fungus is nearly circumglobal. In May 2009, leaves of Bradford pear (Pyrus calleryana Decne.), some di...

  8. Undergraduate Physical Education Programs: Issues and Approaches.

    ERIC Educational Resources Information Center

    Lawson, Hal A., Ed.

    Papers presented at the National Professional Preparation Conference in Physical Education were revised and expanded for publication in this monograph. In part I, two papers, "Professional Preparation Conferences: One More Time" (W. G. Anderson) and "Current Context and Future Curriculum" (M. J. Ellis), set the stage for a presentation of…

  9. Action potential and contraction of Dionaea muscipula (Venus flytrap).

    PubMed

    DI PALMA, J R; MOHL, R; BEST, W

    1961-03-24

    Observation of the action potential and contraction of the leaf of Dionaea muscipula Ellis revealed several interesting phenomena. Two successive stimuli are generally necessary to cause contraction. The first and ineffective stimulus is associated with slow depolarization. The second stimulus has much more rapid depolarization and initiates contraction.

  10. 21st Century Learning and Information Literacy

    ERIC Educational Resources Information Center

    Breivik, Patricia Senn

    2005-01-01

    The faces of immigrant children who had come through Ellis Island with their parents in search of better futures stare out at me from a set of black and white photographs near my desk. The children, frozen in time, are lined up for blocks, waiting for the doors of a public library to open. Access to information was their pathway to a future of…

  11. No Time for Youth--Growth and Constraint in College Students. Student Life and Its Problems.

    ERIC Educational Resources Information Center

    Katz, Joseph; And Others

    Chapter Seven, by Marjorie M. Lazoff, "Residential Groups and Individual Development," describes living conditions, social environment, and reactions to them of several groups of undergraduate men at Stanford University. Chapter Eight, by Ving Ellis, "Students Who Seek Psychiatric Help," is based on interviews and questionnaire data from 493…

  12. What Should Be Explicit in Explicit Grammar Instruction?

    ERIC Educational Resources Information Center

    Nagai, Noriko; Ayano, Seiki; Okada, Keiko; Nakanishi, Takayuki

    2015-01-01

    This article proposes an approach to explicit grammar instruction that seeks to develop metalinguistic knowledge of the L2 and raise L2 learners' awareness of their L1, which is crucial for the success of second language acquisition (Ellis 1997, 2002). If explicit instruction is more effective than implicit instruction (Norris and Ortega 2000),…

  13. The Construct Validity of Grammaticality Judgment Tests as Measures of Implicit and Explicit Knowledge

    ERIC Educational Resources Information Center

    Gutierrez, Xavier

    2013-01-01

    Grammaticality judgment tests (GJTs) have been, and continue to be, frequently used in the field of SLA as a measure of learners' linguistic ability in the second language (L2). However, only a few studies have examined their construct validity as measures of implicit and explicit knowledge (Bowles, 2011; R. Ellis, 2005), and even fewer have…

  14. How Vietnamese Culture Influence on Learning and Teaching English

    ERIC Educational Resources Information Center

    Huong, Phan Thi Thu

    2008-01-01

    Vietnamese has to face a cross-culture issue with the teaching and learning of English as Vietnamese culture is "villagers' culture" which considers relationships in village as family relations and an emphasis "on hierarchical, social order in their dealings with one another" (Ellis, 1995: 9) with a traditional teaching method…

  15. 75 FR 56578 - Renewal of the Advisory Committee on Apprenticeship (ACA), and an Open Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-16

    ..., IIIAFT Administrator, Heat and Frost Insulators and Allied Workers Int'l Union, Lanham, Maryland. Mr..., Director of YouthBuild & Building Futures, The Providence Plan, Providence, Rhode Island. Ms. Phaedra Ellis... President, Workforce Development Division, National Urban League, New York, New York. Mr. Martin...

  16. Case Study of a Computer Based Examination System

    ERIC Educational Resources Information Center

    Fluck, Andrew; Pullen, Darren; Harper, Colleen

    2009-01-01

    Electronic supported assessment or e-Assessment is a field of growing importance, but it has yet to make a significant impact in the Australian higher education sector (Byrnes & Ellis, 2006). Current computer based assessment models focus on the assessment of knowledge rather than deeper understandings, using multiple choice type questions,…

  17. Why Is It Difficult to Grasp the Impacts of the Portuguese Quality Assurance System?

    ERIC Educational Resources Information Center

    Veiga, Amélia; Rosa, Maria João; Dias, Diana; Amaral, Alberto

    2013-01-01

    This article analyses the impacts of the Portuguese quality assurance system on academic cultures, using the Cultural Theory proposed by Douglas (1970, 1982) and developed by Thompson, Ellis and Wildavsky (1990) as an explanatory framework for Portuguese academics' preference formation in relation to quality assessment. The Portuguese higher…

  18. Schools Reaching Out: An Introduction.

    ERIC Educational Resources Information Center

    Heleen, Owen

    1990-01-01

    Introduces an issue devoted to the Schools Reaching Out projects at David A. Ellis School in Roxbury (MA) and Adolph S. Ochs School in New York City. Projects attempt to link the schools with parents and their communities to promote the students' academic and social success. (DM)

  19. Working-Class Women in the Academy: Laborers in the Knowledge Factory.

    ERIC Educational Resources Information Center

    Tokarczyk, Michelle M., Ed.; Fay, Elizabeth A., Ed.

    This volume contains a collection of essays on the issues and concerns that face women from working-class backgrounds who enter academic careers. Following an introduction and transcript of a dialogue between Kate Ellis and Lillain S. Robinson, the essays are as follows: "What's a Nice Working-Class Girl Like You Doing in a Place Like…

  20. Point of Entry

    ERIC Educational Resources Information Center

    Manzo, Kathleen Kennedy

    2007-01-01

    As part of a professional development program organized by the Save Ellis Island Foundation, the exhibits, databases, photo archives, and recorded interviews at the island's museum helps put the nation's current immigration debate into a broader historical context. Teachers at these sessions learn from scholars and park personnel about early…

  1. Planned and Unplanned Aspects of Occupational Choices by Youth. Final Report.

    ERIC Educational Resources Information Center

    Ellis, Robert A.; And Others

    This document includes reports on four subjects relevant to planned and unplanned aspects of occupational choices by youth. (1) "Toward a Morphology of Occupational Choice," by Robert A. Ellis and others, discusses intrinsic features and extrinsic rewards of work, extra-role considerations, and goal perception as major influences on occupational…

  2. 40 CFR 65.14 - Addresses.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Valley Air Quality Management District, 43301 Division Street, Suite 206, Lancaster, CA 93535. (iii) Bay Area Air Quality Management District, 939 Ellis Street, San Francisco, CA 94109. (iv) Butte County Air Quality Management District, 2525 Dominic Drive, Suite J, Chico, CA 95928. (v) Calaveras County...

  3. 40 CFR 65.14 - Addresses.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Valley Air Quality Management District, 43301 Division Street, Suite 206, Lancaster, CA 93535. (iii) Bay Area Air Quality Management District, 939 Ellis Street, San Francisco, CA 94109. (iv) Butte County Air Quality Management District, 2525 Dominic Drive, Suite J, Chico, CA 95928. (v) Calaveras County...

  4. Moving Business and Marketing Education into the 21st Century. Proceedings of the Annual Meeting of the Atlantic Coast Business and Marketing Education Conference (17th, Raleigh, North Carolina, February 18-19, 2000).

    ERIC Educational Resources Information Center

    Parke, David, Ed.

    This document contains 21 presentations from a conference on business and marketing education. The following papers are included: "Microsoft Excel 2000" (Jeff Fuller); "Clueless in the Classroom? Hints To Help!" (Mary W. Evans); "A Strategy To Improve Narrative-Number Linkage in Business Writing" (Ellis A. Hayes);…

  5. Critical Nucleation Field at the Structured Surface of a Superconductor

    DTIC Science & Technology

    1988-08-01

    Marcel Dekker 1969 8. Ginzburg, V.L., Landau, L.D.: Zh. Eksperim. i Tear. Fiz. 20, 1064 (1950) 9. Gor’kov, L.P.: Zh. Eksperim. i Tear. Fiz. 36, 1918...Department of Chemistry Washington, D.C. 20234 Janes Franck Institute - 5640 Ellis Avenue Dr. J. E. Demuth Chicago, Illinois 60637 IBM Corporation

  6. Coupled s-Wave and d-Wave States in the Heavy Fermion Superconductor U sub 1-x Th sub x Be sub 13

    DTIC Science & Technology

    1988-06-01

    2, Edited by R. D. Parks ( Marcell Dekker, New York, 1969), p. 817. 2 and~2 26. The values for O and0 in these expressions are generally not equal...Chemistry Washington, D.C. 20234 Janes Franck Institute 5640 Ellis Avenue Dr. J. E. Demuth Chicago, Illinois 60637 IBM Corporation Thomas J. Watson

  7. The Impact of an Institutional Black Male Leadership Initiative on Engagement and Persistence

    ERIC Educational Resources Information Center

    Barker, Marco J.; Avery, Jared C.

    2012-01-01

    While there has been growing research that explores the impact of race- and cultural-specific student organizations or spaces on Black students and particularly Black males (Dancy, 2011; Harper & Quaye, 2007; McClure, 2006; Museus, 2008; L. Patton, 2006), there have been fewer studies (Ellis, 2009) examining emerging, institutionalized Black…

  8. From Amorphous to Defined: Balancing the Risks of Spiral Development

    DTIC Science & Technology

    2007-04-30

    qb=p`elli= adequacy of available information about the project environment and the potential effects of management actions ( Pich , Loch, & De Meyer...Standford, CA. Perry, W. (1995, May 10). IPPD definition and key tenets (Secretary of Defense Memorandum). Washington, DC: DoD. Pich , M. T., Loch, C.H

  9. A Gift for the Giver: Helping Miss Liberty.

    ERIC Educational Resources Information Center

    Wright, Corinne

    1986-01-01

    This article describes the activities of a secondary social studies teacher as she involved her class--and eventually the entire school--in activities to support the restoration of the Statue of Liberty and Ellis Island. The students raised over $1,000 by producing an ethnic foods cookbook, holding a raffle, and selling buttons. (JDH)

  10. Keeping Black Poetry Alive

    ERIC Educational Resources Information Center

    Mehta, Diane

    2006-01-01

    Thomas Sayers Ellis, assistant professor of creative writing at New York's Sarah Lawrence College, is one of many scholars fighting for the soul of Black poetry, a struggle that takes place largely off-campus. Unless one is accepted into a top-level graduate poetry program, such as Boston University's program or the Iowa Writing Workshop, a poet's…

  11. The Argument-Structure Complexity Effect in Children with Specific Language Impairment: Evidence from the Use of Grammatical Morphemes in French

    ERIC Educational Resources Information Center

    Pizzioli, Fabrizio; Schelstraete, Marie-Anne

    2008-01-01

    Purpose: The hypothesis that the linguistic deficit presented by children with specific language impairment (SLI) is caused by limited cognitive resources (e.g., S. Ellis Weismer & L. Hesketh, 1996) was tested against the hypothesis of a limitation in linguistic knowledge (e.g., M. L. Rice, K. Wexler, & P. Cleave, 1995). Method: The study examined…

  12. A Guide to the Changing Court Rulings on Union Security in the Public Sector: An Introduction.

    ERIC Educational Resources Information Center

    Jascourt, Hugh D.

    1985-01-01

    Introduces two articles that (1) supply the union and management perspectives of the Supreme Court decision in "Ellis vs. Brotherhood of Railway, Airline and Steamship Clerks" and (2) discuss how this decision affects the public sector in the area of education. (MLF)

  13. A Guide to the Changing Court Rulings on Union Security in the Public Sector: A Management Perspective.

    ERIC Educational Resources Information Center

    Clark, R. Theodore, Jr.

    1985-01-01

    In "Ellis vs. Brotherhood of Railway, Airline and Steamship Clerks," the Supreme Court clarified the line between permissible and nonpermissible expenses and what procedures must be available to prevent compulsory subsidization of ideological activity by objecting employees. This article also describes the Court's decisions subsequent to…

  14. Social Networking and the School Adjustment of Karen Refugee Youth from Burma: Determining the Effects of Ethnic Identity, Bonding Social Capital, and Facebook Use

    ERIC Educational Resources Information Center

    Lewis, Lucy D.

    2013-01-01

    In 2011 alone, over 56,000 refugees were admitted to the United States and a third of these individuals were under the age of 18 (Martin & Yankay, 2012). Researchers have found that the social capital developed through close and confiding relationships is instrumental in the academic outcomes of refugee youth (Kia-Keating & Ellis, 2007;…

  15. Readings from...Play as a Medium for Learning and Development.

    ERIC Educational Resources Information Center

    Bergen, Doris, Ed.

    The chapters and essays in this book are drawn from the 1988 edition of "Play as a Medium for Learning and Development." The first chapter, "The Challenge of Educational Play," by Bernard Spodek and Olivia N. Saracho, is followed by two essays: (1) "Play and the Origin of Species," (Michael J. Ellis); and (2)…

  16. Second Language Research Forum Colloquia 2009: Colloquium--Measuring the Effectiveness of Focus on Form

    ERIC Educational Resources Information Center

    Loewen, Shawn

    2011-01-01

    Focus on form, i.e. brief attention to language items within a larger meaning-focused context (Long 1991; Ellis 2001), occurs in a variety of L2 instructional contexts. Meta-analyses of the effectiveness of focus on form have found overall positive effects; however, these meta-analyses have commented on the small number of studies available for…

  17. Promoting and Assessing Mathematical Generalising

    ERIC Educational Resources Information Center

    Hill, Tiffany; Lannin, John; van Garderen, Delinda

    2015-01-01

    Helping students generalise mathematical ideas is an essential component of teaching and learning of mathematics (Lannin, Ellis, Elliott & Zbiek, 2011). However, it can be challenging for primary teachers to assess and promote generalisation. Because generalisation is an essential part of mathematics instruction, the authors highlight the…

  18. Making Sense of Frequency.

    ERIC Educational Resources Information Center

    Larsen-Freeman, Diane

    2002-01-01

    Responds to Ellis (2002), which focuses on frequency in language processing, language use, and language acquisition. Contextualizes the frequency factor in terms of the evolution of second language acquisition (SLA) research. Suggests that although relevant and important, the frequency factor requires greater definition and qualification.…

  19. The Contribution of Domain-Specific Knowledge in Predicting Students' Proportional Word Problem Solving Performance

    ERIC Educational Resources Information Center

    Jitendra, Asha K.; Lein, Amy E.; Star, Jon R.; Dupuis, Danielle N.

    2013-01-01

    Proportional thinking, which requires understanding fractions, ratios, and proportions, is an area of mathematics that is cognitively challenging for many children and adolescents (Fujimura, 2001; Lamon, 2007; Lobato, Ellis, Charles, & Zbiek, 2010; National Mathematics Advisory Panel [NMAP], 2008) and "transcends topical barriers in adult…

  20. A Usage-Based Investigation of L2 Lexical Acquisition: The Role of Input and Output

    ERIC Educational Resources Information Center

    Crossley, Scott; Kyle, Kristopher; Salsbury, Thomas

    2016-01-01

    This study investigates relations between second language (L2) lexical input and output in terms of word information properties (i.e., lexical salience; Ellis, 2006a). The data for this study come from a longitudinal corpus of naturalistic spoken data between L2 learners and first language (L1) interlocutors collected over a year's time. The…

  1. Interaction and Syntactic Priming: English L2 Speakers' Production of Dative Constructions

    ERIC Educational Resources Information Center

    McDonough, Kim

    2006-01-01

    Interaction research about the role of language production in second language (L2) development has focused largely on modified output, specifically learners' responses to negative feedback (Iwashita, 2001; Loewen & Philp, in press; Mackey & Philp, 1998; McDonough, 2005; McDonough & Mackey, in press; Nobuyoshi & Ellis, 1993; Pica, 1988; Shehadeh,…

  2. Parlaying the Prison Experience

    ERIC Educational Resources Information Center

    Gray, Katti

    2010-01-01

    At the close of almost 25 years of winding through New York state's prisons, former Black Panther Eddie Ellis walked away in 1994 with four college degrees he earned while incarcerated and kept treading his singular path as an activist on the issues of police, courts, crime and punishment. He then established the Center for NuLeadership on Urban…

  3. The Introductory Mathematics Curriculum: Misleading, Outdated, and Unfair and Responses .

    ERIC Educational Resources Information Center

    Roberts, Fred S.; And Others

    1984-01-01

    Roberts discusses his perception that the college introductory curriculum in mathematics is outdated. Reactions are then presented from Lucas, Hamming, Tall, David, Ellis, Thompson, Mason, and Guy, with a response by Roberts. The need to change instructional methods as well as curriculum is noted by most. (MNS)

  4. Prescriptions: Hyperrealism and the Chemical Regulation of Mood

    ERIC Educational Resources Information Center

    Bleakley, Alan; Jolly, Margaretta

    2012-01-01

    Using contemporary literary sources, we explore the powerful ideological framework that normalises prescription dependency as part of everyday life, focusing upon the treatment of mood disorders. Through a literary critical methodology, we read novels by American hyperrealists such as Bret Easton Ellis, David Foster Wallace and Rick Moody as…

  5. The Role(s) of Heparan Sulfate Proteoglycan(s) in the wnt-1 Signaling Pathway

    DTIC Science & Technology

    1998-08-01

    and invertebrates , and are initiated by formation of a polysaccharide chain consisting of (D-glucuronic acido....N-acetyl-D- glucosamine...M.C. Ellis, T.B. Kornberg, and C.S. Goodman. 1989. Expression of Engrailed protein in arthropods, annelids and chordates . Cell 58: 955-968. Patel N.H

  6. Respiratory Onset Detection Using Variance Fractal Dimension

    DTIC Science & Technology

    2007-11-02

    V.R., 1994. “The synchronization of respiration and swallow sounds with videofluroscopy during swallowing”. Dysphagia 9, 162-167 [3] Tarrant S.C, Ellis...R.E, Flack F.C, and Selley W.G., 1997. “Comparative review of techniques for recording respiratory events at rest and during deglutition”, Dysphagia

  7. Quality Assurance for University Teaching.

    ERIC Educational Resources Information Center

    Ellis, Roger, Ed.

    This book, written from a British perspective, presents 17 papers on quality assurance in teaching at the university level. The first eight papers address issues of assuring quality and include: (1) "Quality Assurance for University Teaching; Issues and Approaches" (Roger Ellis); (2) "A British Standard for University…

  8. Interior detail, building 810, view to north showing curved chord ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior detail, building 810, view to north showing curved chord sections of roof trusses, 90mm lens plus electronic flash fill lighting. - Travis Air Force Base, B-36 Hangar, Between Woodskill Avenue & Ellis, adjacent to Taxiway V & W, Fairfield, Solano County, CA

  9. On JALT 95: Curriculum and Evaluation. Proceedings of the JALT International Conference on Language Teaching/Learning (22nd, Nagoya, Japan, November 1995). Section Seven: Testing and Evaluation.

    ERIC Educational Resources Information Center

    Brown, James Dean; And Others

    This section contains conference papers on testing and evaluation in second language teaching. They include: "English Language Entrance Examinations in Japan: Problems and Solutions" (James Dean Brown); "Reliability and a Learner Style Questionnaire" (Dale T. Griffee); "Does It Work?" Evaluating Language Learning Tasks" (Rod Ellis); "Communicative…

  10. 76 FR 71598 - Pearl Harbor National Wildlife Refuge, Honolulu County, HI; Final Comprehensive Conservation Plan...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-18

    ... Fish and Wildlife Service Pearl Harbor National Wildlife Refuge, Honolulu County, HI; Final... http://www.fws.gov/pacific/planning/main/docs/HI-PI/docsjcpearl.htm . Email: Laura_Beauregard@fws.gov... Kamehameha Highway, Room 2C, Hale`iwa, HI 96712. FOR FURTHER INFORMATION CONTACT: David Ellis, Project...

  11. 76 FR 38414 - James Campbell National Wildlife Refuge, Honolulu County, HI; Draft Comprehensive Conservation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-30

    ... Fish and Wildlife Service James Campbell National Wildlife Refuge, Honolulu County, HI; Draft... Highway, Room 2C, Hale`iwa, HI 96712. FOR FURTHER INFORMATION CONTACT: David Ellis, Project Leader, (808... Leader, O`ahu National Wildlife Refuge Complex, 66-590 Kamehameha Highway, Room 2C, Hale`iwa, HI...

  12. International Review of Research in Mental Retardation.

    ERIC Educational Resources Information Center

    Ellis, Norman R., Ed.

    The text of Volume 4 represents an international review of research in mental retardation dealing primarily with human and animal laboratory behavior. The contents range through the following topics: memory processes in retardates and normals by Norman Ellis; a theory of primary and secondary familial mental retardation by Arthur Jensen;…

  13. Missionary Girl Power: Saving the "Third World" One Girl at a Time

    ERIC Educational Resources Information Center

    Sensoy, Ozlem; Marshall, Elizabeth

    2010-01-01

    Deborah Ellis's "The Breadwinner" is a popular young adult novel about Muslim girls. In this paper, we offer an analysis of the representation of Muslim girls and women in the book as well as responses from undergraduate students enrolled in a children's literature course to these constructions. Building on the work of postcolonial feminism…

  14. The Federal Government's Relationship to the Nationally Recognized Accrediting Agencies.

    ERIC Educational Resources Information Center

    Office of Education (DHEW), Washington, DC.

    Proceedings include: the keynote address (John Ellis); themes and questions on accreditation and institutional eligibility (David A. Trivett); the task force on futuristic Office of Education criteria for recognition (Samuel P. Martin); possible accreditation agency uses of the products of the Office of Education project on improving the consumer…

  15. Reconsidering Metaphorical Performance of EFL Learners with a Focus on Their Cognitive Features

    ERIC Educational Resources Information Center

    Soureshjani, Kamal Heidari; Safikhani, Arezoo

    2012-01-01

    Metaphoric language and understanding such a language have been of central concern in not only private language schools for intermediate and advanced learners, but in universities for students whose major is English. Besides, as Ellis (1994) maintains, various individual differences have an effect on students' performance and learning. One of the…

  16. Impacted tooth

    MedlinePlus

    ... management of impacted teeth. In: Hupp JR, Ellis E, Tucker MR, eds. Contemporary Oral and Maxillofacial Surgery . 6th ed. St. Louis, MO: Elsevier Mosby; 2014:chap 9. Read More Abscess Review Date 2/22/2016 Updated by: Michael Kapner, DDS, general and aesthetic dentistry, Norwalk Medical ...

  17. Dry socket

    MedlinePlus

    ... management of extraction complications. In: Hupp JR, Ellis E, Tucker MR, eds. Contemporary Oral and Maxillofacial Surgery . 6th ed. St. Louis, MO: Elsevier Mosby; 2014:chap 11. Review Date 11/10/2016 Updated by: Michael Kapner, DDS, General Dentistry, Norwalk, CT. Review provided ...

  18. 77 FR 75636 - Baldev Raj Bhutani; Denial of Hearing on Application for Special Termination of Debarment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-21

    ..., committed and that he cooperated with FDA in resolving outstanding civil matters involving Alra and him on.... \\1\\ See United States v. Ellis, 527 F.3d. 203, 206 (1st Cir. 2008) (holding that ``substantial.... Bhutani, in any capacity during his period of debarment, will be subject to civil money penalties...

  19. Finding My Voice: [Re]living, [Re]learning, and [Re]searching Becoming a Singer in a Culture of Marginalization

    ERIC Educational Resources Information Center

    Manovski, Miroslav Pavle

    2012-01-01

    Boys who sing in school are often marginalized, taunted, sometimes called "gay." What if "singer" is someone's whole identity, and that person also happens to be gay? This autoethnography (Ellis, 2004) is a story of the education and development of such a singer and how, within this context, a voice teacher with an empowering…

  20. Promises & Challenges. Proceedings of the Annual Conference on Multimedia in Education & Industry (2nd, Savannah, Georgia, July 29-31, 1993).

    ERIC Educational Resources Information Center

    Association for Applied Interactive Multimedia, Columbia, SC.

    This proceedings of the Association for Applied Interactive Multimedia 1993 conference includes the following papers: "Multimedia in Education and Training: 'Promises and Challenges'" (H. D. Ellis); "Critical Thinking in the Multimedia, Self-Paced English Classroom" (L. Mortensen); "Computer Assisted Instruction" (C.…

  1. Risk Assessment for the Explosive Washout Lagoons (Site 4), Umatilla Depot Activity Hermiston, Oregon

    DTIC Science & Technology

    1992-03-01

    eti, 1985; Soares and Lock, 1980) revealed no additional data. Studies by Lee Ltji. (1978) and Ellis It jd. (1979) demonstrated depressed ...an acclimated microbiota . The leaching and transport of explosives as suspended particulates may lead to contamination of groundwater and nearby

  2. Opulence to Decadence: "The Outsiders" and "Less than Zero."

    ERIC Educational Resources Information Center

    Seay, Ellen A.

    1987-01-01

    Compares and contrasts two adolescent novels, S. E. Hinton's "The Outsiders," and B. Ellis' recent "Less than Zero." Argues for the social relevance and educational worth of both novels, showing that they raise moral and social issues teens need to think about and are already confronting. (JG)

  3. Smart Books: Thinking with a Purpose Across the Curriculum. Media Corner.

    ERIC Educational Resources Information Center

    Coleman, Rhoda, Ed.

    1995-01-01

    Presents reviews of four CD-ROM products developed by Scholastic Books, Inc. Maintains that each of the programs makes extensive use of primary sources and heighten student interest. Discusses products that cover Greek mythology, the sinking of the "Titanic," Malcolm X, and immigrants at Ellis Island. (CFR)

  4. The Employment Context. The Impact of the Law on the Lives of Women. Gender and American Law Series, No. 3.

    ERIC Educational Resources Information Center

    Maschke, Karen J., Ed.

    This book contains the following 14 articles on the effects of law on women in the United States: "Protection of Women Workers and the Courts: A Legal Case History" (Ann Corinne Hill); "Sexual Harassment and Race: A Legal Analysis of Discrimination" (Judy Trent Ellis); "Comparable Worth: Is This a Theory for Black Workers?" (Judy Scales-Trent);…

  5. Democratizing Academic Writing: A Revision of an Experience of Writing an Autoethnographic Dissertation in Color

    ERIC Educational Resources Information Center

    Polanco, Marcela

    2013-01-01

    In this paper, I revise my experience of writing an autoethnographic (Ellis, 2004) dissertation in the field of family therapy as a Colombian mestiza. I discuss how I grappled with my writing, and, in the process, stumbled into matters of democratizing texts. I problematize male-dominant academic standards, telling of the tensions when maneuvering…

  6. Testing a Threshold: An Approximate Replication of Johnson, Mercado & Acevedo 2012

    ERIC Educational Resources Information Center

    Johnson, Mark D.; Nicodemus, Christine L.

    2016-01-01

    In order to better understand the role of working memory in second language (L2) written production, this study contributes to recent research attempting to apply Kellogg's model of working memory in first language (L1) writing to L2 writing research (Ellis & Yuan 2004; Ong & Zhang 2010; Johnson, Mercado & Acevedo 2012). This paper…

  7. Great Facts for September.

    ERIC Educational Resources Information Center

    Hansen, Karen L.

    1992-01-01

    Offers answers to questions on this issue's September calendar of events for elementary students. Items addressed include the Viking 2 spacecraft, children's poetry, Ellis Island, the space shuttle Discovery, space satellites and space junk, ice cream cones, Dr. Seuss, and the praying mantis. (SM)

  8. Screening of microbial volatile organic compounds for detection of disease in cattle: development of lab-scale method

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The quest to find unique marker volatile organic compounds (VOCs) associated with human, livestock and wildlife diseases (Ellis et al., 2014) requires development of diagnostic non-invasive point-of-care tools and field surveillance technologies and strategies. The objective of this research was to ...

  9. Information-Seeking Behavior in the Digital Age: A Multidisciplinary Study of Academic Researchers

    ERIC Educational Resources Information Center

    Ge, Xuemei

    2010-01-01

    This article focuses on how electronic information resources influence the information-seeking process in the social sciences and humanities. It examines the information-seeking behavior of scholars in these fields, and extends the David Ellis model of information-seeking behavior for social scientists, which includes six characteristics:…

  10. Learning Style and Task Performance in Synchronous Computer-Mediated Communication: A Case Study of Iranian EFL Learners

    ERIC Educational Resources Information Center

    Hedayati, Mohsen; Foomani, Elham Mohammadi

    2015-01-01

    The study reported here explores whether English as a foreign Language (EFL) learners' preferred ways of learning (i.e., learning styles) affect their task performance in computer-mediated communication (CMC). As Ellis (2010) points out, while the increasing use of different sorts of technology is witnessed in language learning contexts, it is…

  11. Categories of Counselors Behavior as Defined from Cross-Validated Factoral Descriptions.

    ERIC Educational Resources Information Center

    Zimmer, Jules M.; And Others

    The intent of the study was to explore and categorize counselor responses. Three separate filmed presentations were shown. Participating with the same client were Albert Ellis, Frederick Perls, and Carl Rogers. At the beginning of each counselor statement, a number was inserted in sequence and remained on the videotape until completion of that…

  12. Pedagogical Moments: Affective Sexual Literacies in Film

    ERIC Educational Resources Information Center

    Clarke, Kyra

    2013-01-01

    This paper considers three pedagogical moments in the film "Tomorrow, When the War Began" (2010), contemplating the way in which they open a space for conversations about feelings, sexuality and gender. "Tomorrow, When the War Began" follows the plight of 17-year-old Ellie who returns to her rural town from a camping trip with…

  13. Adaptive Calibration of Children's Physiological Responses to Family Stress: The Utility of Evolutionary Developmental Theory--Comment on Del Giudice et al. (2012) and Sturge-Apple et al. (2012)

    ERIC Educational Resources Information Center

    Bugental, Daphne Blunt

    2012-01-01

    Children's physiological reactions to stress are presented from the broader theoretical perspective of adaptive calibration to the environment, as rooted in life history theory. Del Giudice, Hinnant, Ellis, and El-Sheikh (2012) focus on children's physiological responses to a stressful task as a consequence of their history of family stress.…

  14. The Effect of Orthophosphate as a Copper Corrosion Inhibitor in High Alkalinity Drinking Water Systems

    DTIC Science & Technology

    2007-03-01

    the cold-water sample faucet was turned on for one minute. The faucet was turned off, then dried with a paper towel . D. The LDPE sample collection...Sussex, England: Ellis Horwood, 1989. McClave, James T., Benson, P. George, and Sincich, Terry . Statistics for Business and Economics, 9th Edition

  15. [Difficult fiberoptic tracheal intubation in 1 month-old infant with Treacher Collins Syndrome].

    PubMed

    Fuentes, Ricardo; De la Cuadra, Juan Carlos; Lacassie, Hector; González, Alejandro

    2016-09-27

    Neonates and small infants with craniofacial malformation may be very difficult or impossible to mask ventilate or intubate. We would like to report the fiberoptic intubation of a small infant with Treacher Collins Syndrome using the technique described by Ellis et al.

  16. 77 FR 27847 - Qualification of Drivers; Exemption Applications; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-11

    ... left eye, 20/20. Following an examination in 2012, his optometrist noted, ``Mr. Ellis demonstrates.... Following an examination in 2012, his optometrist noted, ``Mr. Epps has sufficient visiual stability to... in his left eye, 20/20. Following an examination in 2012, his optometrist noted, ``In my...

  17. Clients as Teachers.

    ERIC Educational Resources Information Center

    Journal of Counseling and Development, 1988

    1988-01-01

    Contains eight accounts: "But Kids Don't Commit Suicide" (Sharon Andreozzi); "Learning from Multiplicity" (Kathryn Ellis); "Autonomy, Control, and Affiliation: Your Issues or Mine?" (Claudia Haferkamp); "Role Players" (Dennis Heitzmann); "Grief Counseling: Facilitating the Healing Process" (Rosemary Hughes); "Hospital Referral: A Test of Counselor…

  18. Temporal Fluctuations in Foreign Language Motivation: Results of a Longitudinal Study

    ERIC Educational Resources Information Center

    Kruk, Mariusz

    2016-01-01

    According to Ellis (2008), motivation has received a lot of interest in language learning. It is unfortunate, however, that little attention has been paid to the dynamic nature of the construct, particularly changes in motivation within single classes and series of lessons. The study whose results are reported in this paper aims at investigating…

  19. Participatory Formative Assessment in an Environment of High-Stakes Testing: An Autoethnography

    ERIC Educational Resources Information Center

    Johnson, Karin Pogna

    2011-01-01

    The purpose of this study was to describe my experiences as a campus principal in facilitating the use of participatory formative assessment (PFA) in an environment of accountability and high-stakes testing. The methodology I employed was autoethnography (Chang, 2008; Ellis, 2004; Reed-Danahay, 1997; Stinson, 2009). I kept journals over a period…

  20. 40 CFR 81.337 - Oklahoma.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Intrastate Unclassifiable/Attainment Alfalfa County Beaver County Blaine County Cimarron County Custer County.../Attainment Alfalfa County Beaver County Blaine County Cimarron County Custer County Dewey County Ellis County.... Beaver County Unclassifiable/Attainment. Beckham County Unclassifiable/Attainment. Blaine...

  1. 40 CFR 81.337 - Oklahoma.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Intrastate Unclassifiable/Attainment Alfalfa County Beaver County Blaine County Cimarron County Custer County.../Attainment Alfalfa County Beaver County Blaine County Cimarron County Custer County Dewey County Ellis County... 187Northwestern Oklahoma Intrastate Unclassifiable/Attainment Alfalfa County Beaver County Blaine County...

  2. 40 CFR 81.337 - Oklahoma.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Intrastate Unclassifiable/Attainment Alfalfa County Beaver County Blaine County Cimarron County Custer County.../Attainment Alfalfa County Beaver County Blaine County Cimarron County Custer County Dewey County Ellis County.... Beaver County Unclassifiable/Attainment. Beckham County Unclassifiable/Attainment. Blaine...

  3. The Fight over Screening Students to Prevent Suicide

    ERIC Educational Resources Information Center

    Ashford, Ellie

    2005-01-01

    An article by Ellie Ashford condensed from School Board News (Jun 28, 2005) is presented in this article. Proponents of mental health screening point to stories to illustrate the benefits of screening seemingly healthy teenagers. Yet, opposition to mental health screening is growing, with one school health expert calling it "as controversial…

  4. An Attempt to Elaborate a Construct to Measure the Degree of Explicitness and Implicitness in ELT Materials

    ERIC Educational Resources Information Center

    Criado Sanchez, Raquel; Perez, Aquilino Sanchez; Gomez, Pascual Cantos

    2010-01-01

    The concepts of "explicit" and "implicit" (knowledge) are at the core of SLA studies. We take "explicit" as conscious and declarative (knowledge); "implicit" as unconscious, automatic and procedural (knowledge) (DeKeyser, 2003; R. Ellis, 2005a, 2005b, 2009; Hulstjin, 2005; Robinson, 1996; Schmidt, 1990, 1994). The importance of those concepts and…

  5. 75 FR 25794 - Regulated Navigation Area: Red Bull Air Race World Championship, Upper New York Bay, Lower Hudson...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-10

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA08 Regulated Navigation Area: Red Bull Air Race World... State Park, New Jersey and Ellis Island, New Jersey and New York for the Red Bull Air Race World Championship, an event scheduled to be held over water. This regulation is necessary to protect...

  6. Irrational Beliefs of Shoplifters.

    ERIC Educational Resources Information Center

    Solomon, Gary S.; Ray, Joseph B.

    1984-01-01

    Developed and tested the Shoplifter Offenders Program (SOP) which uses the principles of Ellis' rational-emotive therapy (RET) as the conceptual foundation for the intensive, 8-hour, psychoeducational group counseling experience with adult first offender shoplifters (N=94). Results showed a recidivism rate of approximately one percent. (LLL)

  7. Implicit Knowledge, Explicit Knowledge, and Achievement in Second Language (L2) Spanish

    ERIC Educational Resources Information Center

    Gutierrez, Xavier

    2012-01-01

    Implicit and explicit knowledge of the second language (L2) are two central constructs in the field of second language acquisition (SLA). In recent years, there has been a renewed interest in obtaining valid and reliable measures of L2 learners' implicit and explicit knowledge (e.g., Bowles, 2011; R. Ellis, 2005). The purpose of the present study…

  8. Urban Ecosystems Research Joins Mainstream Ecology

    EPA Science Inventory

    We appreciate the heightened awareness that Zoë Corbyn’s article brings about the ostensible dearth of urban ecology studies and we laud the efforts of Martin, Ellis, and Blossey to quantify urban research efforts (“Ecologists shun the urban jungle”, online 16 July 2010; http://w...

  9. Pedagogical Effectiveness and Feasibility of Focus on Form vs. Focus on Meaning in a Reading Class: Compatibility of Teacher-Learner's Perspectives

    ERIC Educational Resources Information Center

    Abbasian, Gholam-Reza; Pooshaneh, Leila

    2015-01-01

    Many empirical investigations have demonstrated that explicit Focus on Form (FOF) methods are more effective than implicit Focus on Meaning (FOM) methods (Norris & Ortega, 2000), because in FOF instruction learners' attention is drawn to linguistic form while FOM instruction requires learners' attention to communicate (Ellis, 2001). However,…

  10. An Examination of the Relationship between Irrational Beliefs and Communication Apprehension.

    ERIC Educational Resources Information Center

    Ambler, Bob; Elkins, Mike

    A study of the relationship between irrational beliefs and communication apprehension (CA) sought to determine (1) if CA is related to a person's irrational beliefs as defined in research by Ellis; (2) to which, if any, of the CA contexts (group, meeting, dyadic, or public speaking) the irrational beliefs are most related; and (3) whether the…

  11. Edge-Splitting in a Cumulative Multimodal System, for a No-Wait Temporal Threshold on Information Fusion, Combined with an Under-Specified Display

    DTIC Science & Technology

    2006-01-01

    enough confidence on the state of the interpretation, as suggested in Neem [11]. The form in which a system manifests an interpretation – the...ICMI, Workshop on Multimodal, Multiparty Meeting Processing. 2005. Trento, Italy. [11] Barthelmess, P. and C.A. Ellis, The Neem Platform: an Evolvable

  12. Health Instruction Packages: Injections.

    ERIC Educational Resources Information Center

    Dunkleman, Ellie; And Others

    Text, illustrations, and exercises are utilized in this set of four learning modules designed to instruct nursing students in techniques and equipment utilized for intramuscular injections. The first module, "Equipment for Intramuscular Injections" by Ellie Dunkleman, presents guidelines for selecting needles of the proper length and…

  13. Evolution, Stress, and Sensitive Periods: The Influence of Unpredictability in Early versus Late Childhood on Sex and Risky Behavior

    ERIC Educational Resources Information Center

    Simpson, Jeffry A.; Griskevicius, Vladas; Kuo, Sally I-Chun; Sung, Sooyeon; Collins, W. Andrew

    2012-01-01

    According to a recent evolutionary life history model of development proposed by Ellis, Figueredo, Brumbach, and Schlomer (2009), growing up in harsh versus unpredictable environments should have unique effects on life history strategies in adulthood. Using data from the Minnesota Longitudinal Study of Risk and Adaptation, we tested how harshness…

  14. New Materials for Electrochemical Cells.

    DTIC Science & Technology

    1987-06-20

    mW 4. % Fgb ILE UQpj n~~ ’--- ,JUL1497 AD-A 183 659 1EPORT DOCUMENTATION PAGE lb. RESTRICTIVE MARKINGS Unclassafieid C 2.. SECURITY CLASSIFICATION...FY SOURCE: $43184, FY83; $35112, FY84; $47974, FY85; $59892, FY86; 6. SENIOR RESEARCH PERSONNEL: B. Ellis S. Hibble S. Pericard R.A. Burnham M.T

  15. My Granddaughter

    ERIC Educational Resources Information Center

    Wardle, Francis

    2009-01-01

    In this article, the author describes his granddaughter Elly (Elysia), who is just over a year old. While he deeply enjoys her company as a granddaughter--after all, her favorite activity is to pull his graying beard--as an instructor of child psychology, both for early childhood and psychology students, the author is fascinated with observing…

  16. School Counselor Supervisors' Perceptions of the Discrimination Model of Supervision

    ERIC Educational Resources Information Center

    Luke, Melissa; Ellis, Michael V.; Bernard, Janine M.

    2011-01-01

    The authors examined 38 school counselor supervisors' perceptions of the Discrimination Model (DM; Bernard, 1979, 1997) of supervision, replicating and extending Ellis and Dell's (1986) investigation of the DM with mental health counselor supervisors. Participants judged the dissimilarity of each unique combination of roles and foci of the DM. The…

  17. Water Quality Criteria for Nitroglycerin.

    DTIC Science & Technology

    1986-07-01

    International Labour Office 1983). and in the treatment of angina pectoris (Ellis et al. 1984). The objectives of this report are to review the available data...alcohol intolerance, heart palpitation, and angina pectoris (NIOSH 1978; Stokinger 1982). Availa- ble information indicates that continued exposure to

  18. Development of Measures of Success for Corporate Level Air Force Acquisition Initiatives

    DTIC Science & Technology

    2006-04-30

    Accounting, 74(41) (October 1992). Ellis, L. and C. Curtis. “ Measuring Customer Satisfaction ,” Research Technology Management, 38(5): 45-48... Measuring Customer Satisfaction . Milwaukee WI: Quality Press, 1992. International Council on Systems Engineering (INCOSE) Measurement Working Group

  19. Development of Measures of Success for Corporate Level Air Force Acquisition Initiatives

    DTIC Science & Technology

    2004-03-01

    System to Measure Performance,” Management Accounting, 74(41) (October 1992). Ellis, L. and C. Curtis. “ Measuring Customer Satisfaction ,” Research...The Agenda: What Every Business Must Do to Dominate the Decade. New York: Crown Business, 2001. Hayes, B. Measuring Customer Satisfaction . Milwaukee

  20. 76 FR 58262 - American River Power I, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-20

    ..., Ohio--Water Power Project No. 14257 to be located at the existing Ellis Ohio Lock Dam No. 11 on the... Energy Regulatory Commission American River Power I, LLC; Notice of Preliminary Permit Application..., 2011, American River Power I, LLC (American River) filed an application for a preliminary...

  1. Race, Change, and Urban Society. Urban Affairs Annual Reviews, Volume 5.

    ERIC Educational Resources Information Center

    Orleans, Peter, Ed.; Ellis, William Russell, Jr., Ed.

    Contents of this book include 20 chapters: (1) "Race Research: 'Up Against the Wall' in More Ways Than One," W.R. Ellis, Jr. and P. Orleans; (2) "Value Premises in Race Research: The Evolution of Environmentalism," E.L. Paynter; (3) "Power in the Reformulation of Race Research," I. Katznelson; (4) "Caste and Race Conflict in Cross-Cultural…

  2. Nurturing Potential. Annual SAGE (Society for the Advancement of Gifted Education) Conference Proceedings (4th, Edmonton, Alberta, Canada, September 24-25, 1993).

    ERIC Educational Resources Information Center

    Calgary Univ. (Alberta). Centre for Gifted Education.

    This proceedings contains summaries of 24 conference papers focusing on new directions in gifted education. Each paper's summary is about four pages in length. Papers have the following titles and authors: "Supporting Giftedness in Girls in the Classroom" (Julia Ellis); "A Community of Learners in ECS" (Anne Green);…

  3. 40 CFR 81.323 - Michigan.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    .... Ellis St. and N. Bridge St.) by latitude 43.1033911 N and longitude 85.2278464 W; western boundary 3..., sections 7-36 X AQCR 123 X AQCR 124 (Michigan portion) X AQCR 125 X AQCR 126 X Michigan—2010 Sulfur Dioxide... Sanilac County Shiawassee County Tuscola County AQCR 123 Metro Detroit-Port Huron Intrastate (Remainder...

  4. Beyond Cumulative Risk: Distinguishing Harshness and Unpredictability as Determinants of Parenting and Early Life History Strategy

    ERIC Educational Resources Information Center

    Belsky, Jay; Schlomer, Gabriel L.; Ellis, Bruce J.

    2012-01-01

    Drawing on life history theory, Ellis and associates' (2009) recent across- and within-species analysis of ecological effects on reproductive development highlighted two fundamental dimensions of environmental variation and influence: harshness and unpredictability. To evaluate the unique contributions of these factors, the authors of present…

  5. Services Supply Chain in the Department of Defense: A Comparison of Acquisition Management Practices in the Army, Navy, and Air Force

    DTIC Science & Technology

    2010-08-23

    k^s^i=mlpqdo^ar^qb=p`elli= models; and Schiele and McCue (2006) studied the acquisition of consulting services in the public sector. Although these...Aeronautics and Astronautics. Schiele , J. J., & McCue, C. P. (2006). Professional service acquisition in public sector procurement. International

  6. Using Knowledge about the Opponent in Game-Tree Search.

    DTIC Science & Technology

    1992-09-01

    Futer , Computer analysis of a rook endgame, in Machine Intelligence 9, Hayes, Michie and Mikulich eds. Ellis Horwood Ltd., 1979. [8] E. B. Baum, Minimax...Komissarchik and A.L. Futer , Computer analysis of a queen endgame, The ICCA Journal, Vol. 9, no. 4, December 1986. [27] D. Kopec and T. Niblett, How hard is

  7. Observations on Bubble Dynamics at High Pressures and Bubble Dynamics in Stagnation Flow.

    DTIC Science & Technology

    1982-11-30

    ratio is 1:1.16 in the first expo- picture taken at 200,000 frames per second sure and 1:1.38 in the second. with the laser camera. Cavitacion appears...6, pp. 495-496 (1944). 12. A.T. Ellis, "Techniques for Pressure Pulse Measurements and High Speed Photography in Ultrasonic Cavitation," Paper No. 8

  8. Crossing the Technology Adoption Chasm: Implications for DoD

    DTIC Science & Technology

    2008-06-30

    elli= cowpea varieties for extension education in Southwestern Nigeria. The Journal of Agricultural Education and Extension, 12(3), 195-200. O’Rourke...Adekoya, A.E. (2006). Implication of farmers’ propensity to discontinue adoption of downey-mildew resistant maize and improved cowpea varieties for... Cowpea (Farmer) Feedback Provision (-) Marketability Varieties Input Availability (+) Dependent Variable = De-adoption of Cowpea

  9. Facing the Future.

    ERIC Educational Resources Information Center

    Gallin, Alice, Ed.

    1983-01-01

    Ways that Catholic colleges and universities are trying to fulfill their role are discussed in articles by six college presidents and a church historian. In "The Catholic Liberal Art College: Has It a Future?" John Tracy Ellis notes some of the roots to be reaffirmed by Catholic colleges. In "Preparing for the Millennium," Theodore M. Hesburgh…

  10. Cognitive Therapist: A Dialogue with Aaron Beck.

    ERIC Educational Resources Information Center

    Weinrach, Stephen G.

    1988-01-01

    Presents interview with cognitive therapist Aaron Beck in which Beck describes cognitive therapy; the contributions of Freud, Maslow, Rogers, and Ellis; cultural, class, and gender issues; training of cognitive-behavior therapists; and the future direction of treatment of anxiety and depression. (ABL)

  11. School-Based Support for GLBT Students: A Review of Three Levels of Research

    ERIC Educational Resources Information Center

    Hansen, Anastasia L.

    2007-01-01

    Gay, lesbian, bisexual, and transgender (GLBT) students experience harassment, alienation, and violence in schools. Several school-based interventions have been suggested to provide a safe and effective learning environment for these students, but few have been evaluated or investigated experimentally. This review utilizes A. K. Ellis' (2001)…

  12. Comprehensive Education Bolivarian-Style: The Alternative School in Barrio Pueblo Nuevo, Venezuela

    ERIC Educational Resources Information Center

    Cole, Mike

    2014-01-01

    In this article, the author traces revolutionary developments in an alternative school in Barrio Pueblo Nuevo, Mérida, in the Bolivarian Republic of Venezuela, a school that caters for students between 4 and 14. He begins by recounting some fieldwork done at the school on his behalf by Edward Ellis in 2010. He goes on to discuss a video made at…

  13. Exploring the Potential of Rehearsal via Automatized Structured Tasks versus Face-to-Face Pair Work to Facilitate Pragmatic and Oral Development

    ERIC Educational Resources Information Center

    Sydorenko, Tetyana V.

    2011-01-01

    Past research has uncovered ways to improve communicative competence, including task-based learner-learner interaction (e.g., R. Ellis, 2003) and task planning (e.g., Mochizuki and Ortega, 2008). Teacher-guided planning particularly increases the benefits of learner-learner interaction (Foster and Skehan, 1999). One component of communicative…

  14. The Potential Importance of Conservation, Restoration and Altered Management Practices for Water Quality in the Wabash River Watershed

    EPA Science Inventory

    The Potential Importance of Conservation, Restoration and Altered Management Practices for Water Quality in the Wabash River Watershed Guoxiang Yang1, Elly P.H. Best2, Staci Goodwin3 1 ORISE Postdoc Research Associate at U.S. Environmental Protection Agency, National Risk...

  15. The Tullahoma Campaign, the Beginning of the End for the Confederacy

    DTIC Science & Technology

    2002-01-01

    1849, Bragg wed Eliza “Elise” Brooks Ellis, a rich daughter of a Louisiana sugar plantation owner, and in 1856 he resigned from the army to try his...by his continual ill health. He suffered from migraine headaches, boils, dyspepsia, chronic diarrhea and rheumatism. His bouts of illness made

  16. Rational Emotive Behavior Therapy with Troubled Students.

    ERIC Educational Resources Information Center

    Zionts, Paul; Zionts, Laura

    1997-01-01

    Based on the early work of Albert Ellis, seeks to identify and challenge irrational beliefs that underlie behavior problems. Outlines concepts and methods of Rational Emotive Behavior Theory and describes the application both in counseling and as a mental health curriculum for troubled children and youth. Offers classroom techniques. (RJM)

  17. Rational Emotive Behavior Therapy: Origins, Constructs, and Applications.

    ERIC Educational Resources Information Center

    Watson, Joshua C.

    In 1956, Dr. Albert Ellis presented his seminal work on Rational Therapy, subsequently renamed Rational Emotive Behavior Therapy (REBT) in 1993. This paper explores the origins, theoretical foundations, applications, and implications of REBT and provides a look at the empirical research available in support of the approach's efficacy. REBT is…

  18. Building Bridge between Learning and Positive Emotion: How to Apply Emotional Factor in Instructional Designing Process?

    ERIC Educational Resources Information Center

    Park, Sanghoon

    2004-01-01

    For millennia, emotional states have been viewed as avoidable impediments to rational thinking (Ellis & Newton, 2000). Several reasons have been pointed out. The lack of consensus of the definition on emotion that tend to conflict with each other was suggested as a main reason (Price, 1998). Also the difficulty of research methodology such as…

  19. An Entropy-based Approach to Detecting Anomalies in Voice over Internet Protocol (VoIP) Traffic

    DTIC Science & Technology

    2010-03-01

    on Applied Computing, Melbourne, Florida, 2003; pp 421—725. 5. J.C. Pelaez ; E.B. Fernandez. VoIP Network Forensic Patterns Published by the U.S...ELLIS J PELAEZ L M MARVEL P GUARINO A PRESSLEY RDRL WML A B FLANDERS D W WEBB A THOMPSON RDRL CIH N C ADAMS RDRL

  20. A Study of University Efforts to Provide Students with the Ability to Comprehend and Apply Total Quality Principles in Their Fields of Study

    DTIC Science & Technology

    1993-09-01

    Pharmacy. Salt Lake City UT. 8 July 1990. Chambers, Ellie. "Work-load and the Quality of Student Learning," Studies in Higher Education , 17: 141-152 (No...Indicator of Educational Quality," Studies in Higher Education 17, No.3: 337-348 (1992). 206 White, John A. Assistant Director, National Science Foundation

  1. The Linguistically Aware Teacher and the Teacher-Aware Linguist

    ERIC Educational Resources Information Center

    McCartney, Elspeth; Ellis, Sue

    2013-01-01

    This review evaluates issues of teacher linguistic knowledge relating to their work with children with speech, language and communication difficulties (SLCD). Information is from Ellis and McCartney [(2011a). "Applied linguistics and primary school teaching." Cambridge: Cambridge University Press], a state-of-the-art text deriving from a British…

  2. From Seeing Adverbs to Seeing Verbal Morphology: Language Experience and Adult Acquisition of L2 Tense

    ERIC Educational Resources Information Center

    Sagarra, Nuria; Ellis, Nick C.

    2013-01-01

    Adult learners have persistent difficulty processing second language (L2) inflectional morphology. We investigate associative learning explanations that involve the blocking of later experienced cues by earlier learned ones in the first language (L1; i.e., transfer) and the L2 (i.e., proficiency). Sagarra (2008) and Ellis and Sagarra (2010b) found…

  3. Learned Attention in Adult Language Acquisition: A Replication and Generalization Study and Meta-Analysis

    ERIC Educational Resources Information Center

    Ellis, Nick C.; Sagarra, Nuria

    2011-01-01

    This study investigates associative learning explanations of the limited attainment of adult compared to child language acquisition in terms of learned attention to cues. It replicates and extends Ellis and Sagarra (2010) in demonstrating short- and long-term learned attention in the acquisition of temporal reference in Latin. In Experiment 1,…

  4. Understanding Proportional Reasoning in Pre-Service Teachers

    ERIC Educational Resources Information Center

    Johnson, Kim H.

    2013-01-01

    The purpose of this study is to examine the proportional reasoning of pre-service teachers at the beginning of their teacher preparation program using the developmental shifts described by Lobato and Ellis (2010). They cast changes in proportional reasoning as transitions or "shifts" in students' thinking and these shifts can serve as…

  5. Beyond Borders: Reading "Other" Places in Children's Literature

    ERIC Educational Resources Information Center

    Stewart, Susan Louise

    2008-01-01

    The author analyzes two texts, Gloria Whelan's "Homeless Bird" and Deborah Ellis's "Parvana's Journey", in an attempt to explain some of the problems and difficulties associated with those texts. The author examines Whelan's representations of India and finds troubling binaries associated with that text. In comparison, the…

  6. The Efficacy of Corrective Feedback and Textual Enhancement in Promoting the Acquisition of Grammatical Redundancies

    ERIC Educational Resources Information Center

    Lyddon, Paul A.

    2011-01-01

    Many second language acquisition researchers (e.g., Doughty & Williams, 1998; R. Ellis, 2007; Long, 1996, 2007; Lyster, Lightbown, & Spada, 1999; Russell & Spada, 2006) have advocated the use of negative feedback to promote learner noticing of errors and the internalization of correct forms. At the same time, the true efficacy of this practice is…

  7. Gender Similarities in Math Performance from Middle School through High School

    ERIC Educational Resources Information Center

    Scafidi, Tony; Bui, Khanh

    2010-01-01

    Using data from 10 states, Hyde, Lindberg, Linn, Ellis, and Williams (2008) found gender similarities in performance on standardized math tests. The present study attempted to replicate this finding with national data and to extend it by examining whether gender similarities in math performance are moderated by race, socioeconomic status, or math…

  8. Grammar Instruction for Adult English Language Learners: A Task-Based Learning Framework

    ERIC Educational Resources Information Center

    Huang, Jiuhan

    2010-01-01

    Over the past few decades, grammar instruction has moved from its central position in traditional language teaching approaches to playing virtually no role in communicative approaches. This article first gives a historical perspective of grammar instruction. Then it outlines the 10 principles of instructed language learning formulated by Ellis and…

  9. Possibilities and Challenges of Learning German in a Multimodal Environment: A Case Study

    ERIC Educational Resources Information Center

    Abrams, Zsuzsanna Ittzes

    2016-01-01

    Despite a growing body of research on task-based language learning (TBLT) (Samuda & Bygate, 2008; Ellis, 2003), there is still little information available regarding the pedagogical design behind tasks and how they are implemented (Samuda & Bygate, 2008). Scholars in computer-mediated second language (L2) learning have called for research…

  10. Measuring University-Level L2 Learners' Implicit and Explicit Linguistic Knowledge

    ERIC Educational Resources Information Center

    Zhang, Runhan

    2015-01-01

    Although many theoretical issues revolving around implicit and explicit knowledge in second language (L2) acquisition hinge on the ability to measure these two types of knowledge, few empirical studies have attempted to do so. However, R. Ellis (2005) did develop a battery of tests intended to provide relatively separate measures. This study aims…

  11. Evaluation of saffron (Crocus sativus L.) adulteration with plant adulterants by (1)H NMR metabolite fingerprinting.

    PubMed

    Petrakis, Eleftherios A; Cagliani, Laura R; Polissiou, Moschos G; Consonni, Roberto

    2015-04-15

    In the present work, a preliminary study for the detection of adulterated saffron and the identification of the adulterant used by means of (1)H NMR and chemometrics is reported. Authentic Greek saffron and four typical plant-derived materials utilised as bulking agents in saffron, i.e., Crocus sativus stamens, safflower, turmeric, and gardenia were investigated. A two-step approach, relied on the application of both OPLS-DA and O2PLS-DA models to the (1)H NMR data, was adopted to perform authentication and prediction of authentic and adulterated saffron. Taking into account the deficiency of established methodologies to detect saffron adulteration with plant adulterants, the method developed resulted reliable in assessing the type of adulteration and could be viable for dealing with extensive saffron frauds at a minimum level of 20% (w/w).

  12. "An aristocracy of talent": the South Carolina physician-naturalists and their times.

    PubMed

    Bryan, Charles S; Whitehead, A Weaver

    2014-01-01

    During the natural history movement of the 18th and early 19th centuries, Charleston as a center was rivaled in the United States only by Philadelphia, New York, and Boston. Prominent physician-naturalists included Alexander Garden (for whom the gardenia is named), John Edwards Holbrook ("father of American herpetology"), and Francis Peyre Porcher (whose Resources of Southern Fields and Forests helped Confederates compensate for drug shortages). The Charleston physician-naturalists belonged to an "aristocracy of talent" as distinguished from the "aristocracy of wealth" of lowcountry planters, who probably did more than any other group to perpetuate slavery and propel the South toward a disastrous civil war. None of the physician-naturalists actively opposed slavery or secession, a reminder that we are all prisoners of the prevailing paradigms and prejudices of our times.

  13. “An Aristocracy of Talent”: The South Carolina Physician-Naturalists and their Times

    PubMed Central

    Bryan, Charles S.; Whitehead, A. Weaver

    2014-01-01

    During the natural history movement of the 18th and early 19th centuries, Charleston as a center was rivaled in the United States only by Philadelphia, New York, and Boston. Prominent physician-naturalists included Alexander Garden (for whom the gardenia is named), John Edwards Holbrook (“father of American herpetology”), and Francis Peyre Porcher (whose Resources of Southern Fields and Forests helped Confederates compensate for drug shortages). The Charleston physician-naturalists belonged to an “aristocracy of talent” as distinguished from the “aristocracy of wealth” of lowcountry planters, who probably did more than any other group to perpetuate slavery and propel the South toward a disastrous civil war. None of the physician-naturalists actively opposed slavery or secession, a reminder that we are all prisoners of the prevailing paradigms and prejudices of our times. PMID:25125748

  14. Polyphenol content and antioxidant activity of fourteen wild edible fruits from Burkina Faso.

    PubMed

    Lamien-Meda, Aline; Lamien, Charles Euloge; Compaoré, Moussa M Y; Meda, Roland N T; Kiendrebeogo, Martin; Zeba, Boukare; Millogo, Jeanne F; Nacoulma, Odile G

    2008-03-06

    A total of fourteen (14) species of wild edible fruits from Burkina Faso were analyzed for their phenolic and flavonoid contents, and their antioxidant activities using the DPPH, FRAP and ABTS methods. The data obtained show that the total phenolic and total flavonoid levels were significantly higher in the acetone than in the methanol extracts.Detarium microcarpum fruit had the highest phenolic and the highest flavonoid content,followed by that of Adansonia digitata, Ziziphus mauritiana, Ximenia americana and Lannea microcarpa. Significant amounts of total phenolics were also detected in the other fruit species in the following order of decreasing levels: Tamarindus indica > Sclerocaryabirrea > Dialium guineense > Gardenia erubescens > Diospyros mespiliformis > Parkiabiglobosa > Ficus sycomorus > Vitellaria paradoxa. Detarium microcarpum fruit also showed the highest antioxidant activity using the three antioxidant assays. Fruits with high antioxidant activities were also found to possess high phenolic and flavonoid contents. There was a strong correlation between total phenolic and flavonoid levels and antioxidant activities.

  15. [Studies on new co-processed excipient consisting of lactose and gelatinized starch].

    PubMed

    Wang, Song-tao; Zhang, Jing; Lin, Xiao; Shen, Lan; Feng, Yi

    2014-11-01

    Co-processed excipients withgelatinized or non-gelatinized starch were prepared by spray drying. Powder and tablet properties of corocessed excipients prepared were compared with those of physical mixtures and spray-dried lactose. Their applicability in traditional Chinese medicine (TCM) powder tableting was tested on two TCM extracts, i.e., the gardenia extract and the Herba Sedi extract. It was shown that gelatinizing starch before co-spray drying with lactose could improve the performance and efficiency of starch as a binder, resulting in remarkable improvement in physicomechanical properties of co-processed excipients prepared. Conpared to self-made and commercially available spray-dried lactose, co-processed excipients achieved better compactability and higher drug loading for TCM extracts. In conclusion, the lactose-gelatinized starch co-processed excipient, with excellent physicomechanical properties, is promising to be explored as a new excipient for direct tableting.

  16. Effect of Traditional Chinese Herbal Medicine with Antiquorum Sensing Activity on Pseudomonas aeruginosa

    PubMed Central

    Zhou, Shuxin; Jiang, Yan; Zhu, Wei; Zhuang, Xiyi; Fu, Jiangyan

    2013-01-01

    Traditional Chinese herbal medicines (TCHMs) were tested for their ability of antiquorum sensing. Water extracts of Rhubarb, Fructus gardeniae, and Andrographis paniculata show antiquorumsensing activity when using Chromobacterium violaceum CV12472 as reporter; the sub-MIC concentrations of these TCHMs were tested against AHL-dependent phenotypic expressions of PAO1. Results showed significant reduction in pyocyanin pigment, protease, elastase production, and biofilm formation in PAO1 without inhibiting the bacterial growth, revealing that the QSI by the extracts is not related to static or killing effects on the bacteria. The results indicate a potential modulation of bacterial cell-cell communication, P. aeruginosa biofilm, and virulence factors by traditional Chinese herbal medicine. This study introduces not only a new mode of action for traditional Chinese herbal medicines, but also a potential new therapeutic direction for the treatment of bacterial infections, which have QSI activity and might be important in reducing virulence and pathogenicity of pathogenic bacteria. PMID:24319480

  17. New distribution record for the rare limpet Acroloxus coloradensis (Henderson) (Gastropoda: Acroloxidae) from Montana

    USGS Publications Warehouse

    Hossack, Blake R.; Robert L. Newell,

    2013-01-01

    The Rocky Mountain Capshell, Acroloxus coloradensis (Henderson, 1930), the only North American member of the basommatophoran family Acroloxidae, is broadly distributed across southern Canada and south into the Rocky Mountains in the USA (Turgeon et al., 1998; Lee and Ackerman, 2000). Despite its wide geographic range, A. coloradensis has been documented from < 30 locations, mostly in British Columbia, Alberta, Ontario, and Quebec (Lee and Ackerman, 2000; Anderson, 2005). Relict populations of A. coloradensis in the USA have been documented from only 6 sites in Colorado and 2 sites in Glacier National Park (Glacier NP), Montana (Anderson, 2005; Ellis et al., 2004). In Glacier NP, A. coloradensis was first reported from Lost Lake (Figure 1; Russell and Brunson, 1967). A second population in the park was discovered in Trout Lake in 2001 (Ellis et al., 2004). In both lakes, A. coloradensis was found primarily under rocks and other cover objects.

  18. Speech-rhythm characteristics of client-centered, Gestalt, and rational-emotive therapy interviews.

    PubMed

    Chen, C L

    1981-07-01

    The aim of this study was to discover whether client-centered, Gestalt, and rational-emotive psychotherapy interviews could be described and differentiated on the basis of quantitative measurement of their speech rhythms. These measures were taken from the sound portion of a film showing interviews by Carl Rogers, Frederick Perls, and Albert Ellis. The variables used were total session and percentage of speaking times, speaking turns, vocalizations, interruptions, inside and switching pauses, and speaking rates. The three types of interview had very distinctive patterns of speech-rhythm variables. These patterns suggested that Rogers's Client-centered therapy interview was patient dominated, that Ellis's rational-emotive therapy interview was therapist dominated, and that Perls's Gestalt therapy interview was neither therapist nor patient dominated.

  19. Abraham Pais Prize for History of Physics: Physics Textbooks Don't Always Tell the Truth

    NASA Astrophysics Data System (ADS)

    Franklin, Allan

    2016-03-01

    Anyone who studies the history of physics quickly realizes that the history of physics presented in physics textbooks is often inaccurate. This is not necessarily a bad thing. The purpose of textbooks is to help students learn physics. An inaccurate history may serve a pedagogical purpose. It may help to explain concepts more clearly than the actual history. I believe, however, that it is important for those of us who teach physics to know the accurate history. In this talk I will discuss two episodes from the history of modern physics, Millikan's experiments on the photoelectric effect and the Ellis-Wooster experiment on the energy spectrum in β decay. Everyone knows that Millikan's work established the photon theory of light. The problem is that what everyone knows is wrong. The Ellis-Wooster experiment, on the other hand, is rarely discussed in physics texts, but it should be. In this talk I will present a more accurate history of these experiments.

  20. Geology and coproduction potential of submarine-fan deposits along the Gulf Coast of east Texas and Louisiana

    SciTech Connect

    Jackson, M.L.W.; Light, M.P.R.; Ayers, W.B. Jr.

    1987-04-01

    Four reservoirs containing dispersed gas were examined for their coproduction potential. Reservoirs in Port Acres field (Texas) and Ellis field (Louisiana) produce from the Hackberry member of the Oligocene Frio formation, and two reservoirs in Esther field (Louisiana) produced from the lower Miocene Planulina zone. Log-pattern and lithofacies maps, together with stratigraphic position, suggest that the reservoirs are in ancient submarine-fan deposits. Dip-elongate, channel-fill sands are characteristic; reservoir sands pinch out along the strike. Growth faults, common in the submarine slope setting, form undip and downdip boundaries, producing combination traps. In Ellis field, coproduction accounts for 300 Mcf/D (8.5X10/sup 3/ m/sup 3//d) of gas. Port Acres field contains the largest remaining reserves, but other technical and economic factors limit coproduction potential there. Recent drilling has extended primary production and delayed coproduction in the Esther field.

  1. Study and modeling of the rheological properties of concentrated water-in-oil emulsions

    SciTech Connect

    Koroleva, M.Yu.; Yurtov, E.V.

    1994-07-01

    Study of the rheological curves of concentrated water-in-oil emulsions indicates that such systems behave like non-Newtonian pseudo-plastic liquids. A number of mathematical models for rheological curves: Chong, Frankel-Acrivos, Ostwald-Weil, Bingham, Stainer, Ferry, Haven, Ellis, and Meter models are considered. The regions of the model adequacy for rheological curves of emulsions with different contents of the dispersed phase are determined. It was shown that only the Ellis model adequately describes the complete rheological curves of concentrated water-in-oil emulsions of the studied composition. Therefore, this model can be applied to the prediction of the viscosity values for emulsions with various phase ratios.

  2. Bounding quantum-gravity-inspired decoherence using atom interferometry

    NASA Astrophysics Data System (ADS)

    Minář, Jiří; Sekatski, Pavel; Sangouard, Nicolas

    2016-12-01

    Hypothetical models have been proposed in which explicit collapse mechanisms prevent the superposition principle from holding at large scales. In particular, the model introduced by Ellis et al. [J. Ellis et al., Phys. Lett. B 221, 113 (1989), 10.1016/0370-2693(89)91482-2] suggests that quantum gravity might be responsible for the collapse of the wave function of massive objects in spatial superpositions. We consider here a recent experiment reporting on interferometry with atoms delocalized over half a meter for a time scale of 1 s [T. Kovachy et al., Nature (London) 528, 530 (2015), 10.1038/nature16155] and show that the corresponding data strongly bound quantum-gravity-induced decoherence and rule it out in the parameter regime considered originally.

  3. Facilitation of receptive and productive foreign vocabulary learning using the keyword method: the role of image quality.

    PubMed

    Beaton, Alan A; Gruneberg, Michael M; Hyde, Christopher; Shufflebottom, Alex; Sykes, Robert N

    2005-07-01

    Ellis and Beaton (1993a) reported that the keyword method of learning enhanced memory of foreign vocabulary items when receptive learning was measured. However, for productive learning, rote repetition was superior to the keyword method. The first two experiments reported here show that, in comparison with rote repetition, both receptive and productive learning can be enhanced by the keyword method, provided that the quality of the keyword images is adequate. In a third experiment using a subset of words from Ellis and Beaton (1993a), the finding they reported, that for productive learning rote repetition was superior to the keyword method, was reversed. The quality of keyword images will vary from study to study and any generalisation regarding the efficacy of the keyword method must take this into account.

  4. Wormhole shadows in rotating dust

    NASA Astrophysics Data System (ADS)

    Ohgami, Takayuki; Sakai, Nobuyuki

    2016-09-01

    As an extension of our previous work, which investigated the shadows of the Ellis wormhole surrounded by nonrotating dust, in this paper we study wormhole shadows in a rotating dust flow. First, we derive steady-state solutions of slowly rotating dust surrounding the wormhole by solving relativistic Euler equations. Solving null geodesic equations and radiation transfer equations, we investigate the images of the wormhole surrounded by dust for the above steady-state solutions. Because the Ellis wormhole spacetime possesses unstable circular orbits of photons, a bright ring appears in the image, just as in Schwarzschild spacetime. The bright ring looks distorted due to rotation. Aside from the bright ring, there appear weakly luminous complex patterns by the emission from the other side of the throat. These structure could be detected by high-resolution very-long-baseline-interferometry observations in the near future.

  5. Physics Textbooks Don't Always Tell the Truth

    NASA Astrophysics Data System (ADS)

    Franklin, Allan

    2016-04-01

    Anyone who studies the history of physics quickly realizes that the history presented in physics textbooks is often inaccurate. I will discuss three episodes from the history of modern physics: (1) Robert Millikan's experiments on the photoelectric effect, (2) the Michelson-Morley experiment, and (3) the Ellis-Wooster experiment on the energy spectrum in β decay. Everyone knows that Millikan's work established the photon theory of light and that the Michelson-Morley experiment was crucial in the genesis of Albert Einstein's special theory of relativity. The problem is that what everyone knows is wrong. Neither experiment played the role assigned to it by physics textbooks. The Ellis-Wooster experiment, on the other hand, is rarely discussed in physics texts, but it should be. It led to Wolfgang Pauli's suggestion of the neutrino. I will present a more accurate history of these three experiments than those given in physics texts.

  6. Anger and the ABC model underlying Rational-Emotive Behavior Therapy.

    PubMed

    Ziegler, Daniel J; Smith, Phillip N

    2004-06-01

    The ABC model underlying Ellis's Rational-Emotive Behavior Therapy predicts that people who think more irrationally should display greater trait anger than do people who think less irrationally. This study tested this prediction regarding the ABC model. 186 college students were administered the Survey of Personal Beliefs and the State-Trait Anger Expression Inventory-Second Edition to measure irrational thinking and trait anger, respectively. Students who scored higher on Overall Irrational Thinking and Low Frustration Tolerance scored significantly higher on Trait Anger than did those who scored lower on Overall Irrational Thinking and Low Frustration Tolerance. This indicates support for the ABC model, especially Ellis's construct of irrational beliefs which is central to the model.

  7. Effect of rational and irrational statements on intensity and 'inappropriateness' of emotional distress and irrational beliefs in psychotherapy patients.

    PubMed

    Cramer, D; Kupshik, G

    1993-09-01

    Ellis's rational-emotive theory postulates that since irrational statements augment emotional distress, replacing irrational with rational statements should lessen distress. This hypothesis was tested in the initial stages of psychotherapy by having 13 and 14 clinical out-patients respectively repeat for one minute either rational or irrational statements about their major presenting psychological problem. The distinction by Ellis & Harper (1975) that 'inappropriate' emotions differ qualitatively from 'appropriate' emotions was also examined. Although the experimental intervention had no effect on a post-test measure of irrational beliefs, patients repeating rational statements had significantly lower appropriate and inappropriate negative emotions at post-test, suggesting that inappropriate emotions do not differ qualitatively from appropriate emotions and that making rational statements may lower emotional distress in patients. Patients reiterating irrational statements showed no change in emotions, implying that these kinds of irrational cognitions may have already been present.

  8. A test of the ABC model underlying rational emotive behavior therapy.

    PubMed

    Ziegler, Daniel J; Leslie, Yvonne M

    2003-02-01

    The ABC model underlying Ellis's Rational Emotive Behavior Therapy predicts that people who think more irrationally should respond to daily stressors or hassles differently than do people who think less irrationally. This study tested this aspect of the ABC model. 192 college students were administered the Survey of Personal Beliefs and the Hassles Scale to measure irrational thinking and daily hassles, respectively. Students who scored higher on overall irrational thinking reported a significantly higher frequency of hassles than did those who scored lower on overall irrational thinking, while students who scored higher on awfulizing and low frustration tolerance reported a significantly greater intensity of hassles than did those who scored lower on awfulizing and low frustration tolerance. This indicates support for the ABC model, especially Ellis's construct of irrational beliefs central to this model.

  9. Mass extinctions and supernova explosions.

    PubMed Central

    Crutzen, P J; Brühl, C

    1996-01-01

    In a recent contribution to this journal Ellis and Schramm [Ellis, J. & Schramm, D. N. (1995) Proc. Natl. Acad. Sci. USA 92, 235-238] claim that supernova explosions can cause massive biological extinctions as a result of strongly enhanced stratospheric NOx (NO + NO2) production by accompanying galactic cosmic rays. They suggested that these NOx productions which would last over several centuries and occur once every few hundred million years would result in ozone depletions of about 95%, leading to vastly increased levels of biologically damaging solar ultraviolet radiation. Our detailed model calculations show, however, substantially smaller ozone depletions ranging from at most 60% at high latitudes to below 20% at the equator. PMID:11607631

  10. Parallel Large-scale Semidefinite Programming for Strong Electron Correlation: Using Correlation and Entanglement in the Design of Efficient Energy-Transfer Mechanisms

    DTIC Science & Technology

    2014-09-24

    RETURN YOUR FORM TO THE ABOVE ADDRESS. University of Chicago 5801 South Ellis Avenue Chicago , IL 60637 -5418 1 ABSTRACT Final Report: Parallel Large-scale...supported 2012: Promotion of PI to Full Professor at The University of Chicago 2014: Quantrell Award to PI from The University of Chicago ...sponsored research. 9 Final Report 2014 David A. Mazziotti The University of Chicago Statement of the Problem Solved Challenges addressed by the

  11. Targeting Microvascular Pericytes in Angiogenic Vessels of Prostate Cancer

    DTIC Science & Technology

    2005-04-01

    tumor fragments in C57BL/6 mouse ( Maglione et al., 2004) (Namba et al., 2004) (Ozerdem and Stallcup, 2003). Four, male TRAMP mice (24 week old...antibodies to inhibit neovascularization. REFERENCES Abramsson A, Berlin 0, Papayan H, Paulin D, Shani M , Betsholtz C. 2002. Analysis of mural cell... Maglione JE, McGoldrick ET, Young LJ, Namba R, Gregg JP, Liu L, Moghanaki D, Ellies LG, Borowsky AD, Cardiff RD, MacLeod CL. 2004. Polyomavirus

  12. JPRS Report, Science & Technology Europe

    DTIC Science & Technology

    2007-11-02

    materials research under microgravity conditions, such as ELLI, AMF of MHF ( Mirror Heating Facility) the Zone Melt- ing Furnace is a resistance-heated...pendently controlled zones. This is another advantage of a resistance-heated furnace over a mirror heating facil- ity. When the experiment requires a...zone, the subdivision into several heating zones will be preferable to the single light focus of a mirror heating facility. In 1987/88, following

  13. Programming Productivity Enhancement by the use of Application Generators by the Use of Application Generators.

    DTIC Science & Technology

    2014-09-26

    RD-Ai58 598 PROGRAMMING PRODUCTIVITY ENHANCEMIENT BY THE USE-O F APPLICATION GENERATORS.. (U) UNIVERSITY OF SOUTHERN CALIFORNIA LOS ANGELES DEPT OF...for Grant No. AFOSR-82-0232 I Programming Productivity Enhancement by the Use of Application Generators June 1, 1982 - May 31, 1985 by Ellis Horowitz...area of Application Generators. Systems such as RAMS, NOMAD and FOCUS had all proven * to be versatile at improving programmer productivity in the

  14. Echoes Across the Pond: Understanding EU-US Defense Industrial Relationships

    DTIC Science & Technology

    2008-05-20

    Kaldor (1981), and is discussed more formally in Franck (1992). Mary Kaldor, The Baroque Arsenal, New York: Hill and Wang, 1981. Raymond E. Franck...in its current form) is more a hedge against KC-135 airframe aging than an embodiment of operationally significant, new technology. Furthermore...rpfkbpp=C=mr_if`=mlif`v= = - 12 - k^s^i=mlpqdo^ar^qb=p`elli= onset of information- age economies, globalization of economic activity, and the Counter RMA

  15. The New Phase of Constitutional Struggle in Venezuela

    DTIC Science & Technology

    2016-07-21

    3 The New Phase of “Constitutional” Struggle in Venezuela R. Evan Ellis1 The magnitude of the victory by the Venezuelan opposition in the December 6...politician Henry Ramos Allup to preside over the Assembly. Indeed, the first acts of Ramos and the new assembly included the removal of the...unconstitutional, or otherwise invalidate laws passed by the new National Assembly. While the appointment of the new judges by the Chavista-dominated

  16. Space Cabin Landing Impact Vector Effects on Human Physiology

    DTIC Science & Technology

    1964-12-01

    December 1964 Journal Article 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Space Cabin Landing Impact Vector Effects on Human Physiology 5b. GRANT NUMBER 5c...Landing Impact Vector Effects on Human Physiology COLONEL JOHN P. STAPP, USAF, MC, and MAJOR ELLIS R. TAYLOR, USAF, MC ABSTRACT stimulation of carotid...LANDING IMPACT VECTOR EFFECTS ON HUMAN PHYSIOLOGY -STAPP AND TAYLOR tion and pallor occurred on exposure to more than 30 facing seated and bottom

  17. Voluntary Dehydration and Electrolyte Losses during Prolonged Exercise in the Heat,

    DTIC Science & Technology

    1984-01-01

    further interest are the effects of many factors on sweat electrolyte composition . Robinson and Robinson have identified seven factors which alter the...1962. The correlation of structure and function in the human eccrine sweat gland. In: W. Montagna, R. A. Ellis and A. I F. Silver (Ed.) Advances of...Corp., pp. 2:7. 21. Mickelson, 0, and A. Keys. 1943. The composition of sweat , with special reference to the vitamins. J Biol Chem 149:479-490. 22

  18. Impact of Export Control and Technology Transfer Regimes: International Perspectives

    DTIC Science & Technology

    2012-01-07

    Impact of Export Control and Technology Transfer Regimes: International Perspectives 7 January 2012 by BGen (Ret.) Raymond E. Franck ...contact: NPS Acquisition Research Program Attn: James B. Greene, RADM, USN, (Ret.) Acquisition Chair Graduate School of Business and Public Policy...k^s^i=mlpqdo^ar^qb=p`elli= About the Authors Raymond (Chip) Franck , PhD, Senior Lecturer, Graduate School of Business & Public Policy, Naval

  19. Information Operations and the Global War on Terror: The Joint Force Commander’s Fight for Hearts and Minds in the 21st Century

    DTIC Science & Technology

    2006-05-31

    IO or have not been involved with exercises that demonstrate its effectiveness.xlii In the recent Kosovo campaign, Vice Admiral James Ellis noted...shown by Tony Karon , “Al-Qaeda Today: Not Winning, But Not Losing, Either”, Time Online, <www.Time.com/time/world/article/0,8599,4845900,00.html [12... Karon , Tony “Al-Qaeda Today: Not

  20. Air Force Follow-On Review. Protecting The Force: Lessons From Fort Hood

    DTIC Science & Technology

    2010-01-01

    Command and Direct Reporting Unit Team Leads AETC Col Bruce Lovely PACAF Col James Strickler NGB Col Ronald Gionta AFSOC Col Brady Reitz USAFE Col...Carla Gammon AMC Col Frank Jones AFSPC Col Gerald Curry AFGSC Col Peter Ellis ACC Col Robert LaBrutta AFRC Col Joseph Vivori USAFE Col Gus Green...Lt Gen Janet Wolfenbarger AFSOC Maj Gen Kurt Cichowski AFOTEC Maj Gen Stephen Sargeant AETC Maj Gen James Whitmore USAFE Maj Gen William Chambers

  1. Bubble Dynamics in Polymer Solutions Undergoing Shear.

    DTIC Science & Technology

    1985-04-01

    20D 23 REYNOLDS NUMBER *10’ FIGURE 1-1. The effect of dilute polymer solutes on hydraulic cavitation inception (Ellis &Ting, 1974). (a) ( b ) FIGURE 1-2...Comparison of cavitation appearance in (a) water and ( b ) dilute aqueous Polyox solution (Ting, 1978). 3 cavitation is significantly altered (Figure...research fall into two distinct (but related) areas. These are (a) Newtonian (or viscous) flow-induced cavitation bubble deformation and ( b ) non

  2. Assessment of the Human Factors Characteristics of the AH-64D Apache Longbow Crew Stations

    DTIC Science & Technology

    2002-03-01

    other Army aviation systems; and • Validation of AH-64D system performance. To address validation of AH-64D system performance, the following operational...military, civil, and commercial aviation communities for pilot workload estimation (Roscoe & Ellis, 1990). It requires pilots to rate the level of...that could be applied to other Army aviation programs. During the survey and interviews, pilots were asked to identify any problems they have

  3. Man-Portability Considerations for an Improved Medium Antiarmor Assault Weapon (IMAAW)

    DTIC Science & Technology

    1981-03-01

    0 Technical Memorandum 6-81 MAN-PORTABILITY CONSIDERATIONS IPOR ANI IMPROVED MEDIUM ANTIARMOR ASSAULT WEAPON (IMAAw) Dominick J. Giordano Samuel T...ASSAULT WEAPON (IMAAW) Dominick J. Giordano Samuel T. Brainerd -. March 1981 APPROVED: US Army Human Ft1gineoving Lahor;it’ry US ARMY HUMAN...Jones, R.D., Randall, R.B., Ellis, P.H., & Bruno , R.S. ŕ Human factors evaluation of two proposed arut infantry/marine fragmentation protective

  4. Photoluminescent Response of Palladium-Cadmium Sulfide and Palladium-Graded Cadmium Sulfoselenide Schottky Diodes to Molecular Hydrogen.

    DTIC Science & Technology

    2014-09-26

    assistance - and helpful discussions. 8 Re ferences 1. Hollingsworth, R. E.; Sites, J. R. 3. Appi . Phys. 1982, 53, 5357 and references therein. 2. Hobson...W. S.; Ellis, A. B. J. Ap. Phys. 1983, 54, 5956 and references therein. 3. Mettler, K. Appi . Phys. 1977, 12, 75. 4. Stephens, R. B. Phys. Rev.. B...1984, 29, 3283. 5. Steele, M. C.; Maclver, B. A. Appi . Phys. Lett. 1976, 28, 687. 6. Yamamoto, N.; Tonomura, S.; Matsuoka-, T.; Tsubomura, H. Surf. Sci

  5. A muscle contracting substance from a plant's closing Fly-Trap.

    PubMed

    Lea, H W

    1976-01-01

    A muscle contracting substance (MCS) occurs in crushed, incubated traps of the insectivorous plant, the Venus Fly-Trap (Dionaea muscipula Ellis). This MCS is provisionally identified as lysophosphatidic acid. More MCS is produced from traps which have been touched than from untouched traps, which may be due to activation of phospholipase D. This enzyme hydrolyses phospholipids of membranes, and could alter the physiological properties of membranes.

  6. Touch receptor of venous flytrap, Dionaea muscipula.

    PubMed

    DiPalma, J R; McMichael, R; DiPalma, M

    1966-04-22

    Numerous small structures (stellate trichomnes) protrude from the surface of marginal hairs, outer leaf surface, and stem of Dionaea muscipula Ellis. None are present inside the trap. Mechanical stimulation causes small action potentials and eventual closure of the trap, independently of the sensitive trigger hairs. Subthreshold stimulation of these structures appears to sensitize the trigger hairs and facilitate closure of the trap. This suiggests that these structures act as touch sensors or receptors.

  7. Proximity Displays for Access Control

    DTIC Science & Technology

    2012-09-01

    conference on Human factors in computing systems, 2011. 8.2 [35] Willis D. Ellis. A Source Book of Gestalt Psychology . Psychology Press, 1999. 3.3...Engineering agrees, listing cybersecurity as one of their Grand Challenges and specifically noting that understanding the psychology of computer users is...should support users in these behaviors. 2.5 Behavioral models Research from cognitive psychology , behavioral economics and the warning sciences pro- vide

  8. Applicability of Visual Analytics to Defence and Security Operations

    DTIC Science & Technology

    2011-06-01

    IEEE. Koffka, K. (1935), Principles of Gestalt Psychology , Harcourt Brace, New York. Kohlhammer, J. and Keim, D. (2007), Visual Analytics in...Forms, in A Source Book of Gestalt Psychology , W. D. Ellis (ed), p. 71-88, Harcourt Brace. Willems, N., Watering, H.v.d. and Wijk, J.J.v. (2009...The Gestalt laws of organization describe how people perceive visual components as organized patterns or wholes, instead of many different parts

  9. Operational Design: Distilling Clarity from Complexity for Decisive Action

    DTIC Science & Technology

    2012-08-01

    Theory.” An address before the Kant Society, Berlin, 7 December 1924, Erlangen, Germany. In Source Book of Gestalt Psychology , trans. Willis D. Ellis...using Union naval forces along the James River. This tactical setback created a major psychological disruption for McClellan. As McClellan’s lead...assistance from specialists. Understanding Gestalt Theory Another critical aspect of understanding frames of reference is Gestalt theory. Christian von

  10. Wave-Powered Unmanned Surface Vehicle as a Station-Keeping Gateway Node for Undersea Distributed Networks

    DTIC Science & Technology

    2012-09-01

    Bay Aquarium Research Institute METOC Meteorology and Oceanography NDBC National Data Buoy Center NOAA Naval Oceanographic and Atmospheric...significant weather events or currents. The tests were done in Monterey Bay, near ocean observation buoy M1 maintained by the Monterey Bay Aquarium Research...5. Tim Richardson GTRI Atlanta, Georgia 6. RADM Jerry Ellis, USN(r), Chair Undersea Warfare Naval Postgraduate School Monterey, California 7. RDML

  11. JPRS Report East Europe.

    DTIC Science & Technology

    1990-06-01

    34 37 There ought to be a even arrested in the GDR (Max Fechner , Max Fank, special research program for this chapter as well as for Willy Jesse, Paul...Anton Ackermann, Franz SED Central Committee or of the Central Party Control Dahlem, Max Fechner , Erich Gniffke, August Karsten, Commission (ZPKK...organized in the fall of 1948, Paul Merker, and Elli Schmidt-of them Fechner and respectively. The Central Committee passed another Merker were arrested and

  12. An Empirical Study of a Vulnerability Metric Aggregation Method

    DTIC Science & Technology

    2011-07-01

    Privacy, pages 254–265, 2002. [15] Laura P. Swiler, Cynthia Phillips, David Ellis, and Stefan Chakerian. Computer-attack graph generation tool. In DARPA...all D atabase Server U ser W orkstations In ternet D M Z Internal U ser Internal F irew all 0: attackerLocated(internet) 1: execCode(dbServer,root...14th USENIX Security Symposium, 2005. [13] Cynthia Phillips and Laura Painton Swiler. A graph-based system for network-vulnerability analysis. In NSPW

  13. An Analysis of the Effect of Knowledge Management on the Execution of Simplified Acquisition Procedures

    DTIC Science & Technology

    2012-12-27

    ar^qb=p`elli= processes” (p. 1). A person with access to a relevant stock of knowledge has a competitive advantage; and, by managing the quality ...Connection website: https://acc.dau.mil/CommunityBrowser.aspx?id=340759&view=w Department of Defense Office of Inspector General. (2012). ISO 9001 ... Management Journal, 24–43. Nissen, M. E., & Rendon, R. (in press). Measuring acquisition workforce quality through dynamic knowledge and performance

  14. Effects of Different Heavy-Resistance Exercise Protocols on Plasma Beta-Endorphin Concentrations

    DTIC Science & Technology

    1993-01-01

    exercise increases in muscular hypertrophy (27). Thus each exer- protocols used previously. Each subject gave informed cise series provides for...ANTE. P. D., AND M. E. HOUSTON. Effects of concentric and DUDLEY. C. M. MARESH, L. MARCHIrELLI, C. CRUTHIRDS, T. eccentric exercise on protein catabolism...DTIC Effects of different heavy-resistance exercise ELECTE protocols on plasma #-endorphin concentrations MAR 3 0 1993 C WILLIAM J. KRAEMER, JOSEPH E

  15. Coosa River Storage Annex, Talladega, Alabama. Environmental Investigation Report. Volume 1 of 2

    DTIC Science & Technology

    1992-09-01

    support populations of herpetofauna ( reptiles and amphibians) that may serve as vector organisms, nor are they known to support populations of crayfish...liver and spleen hypertrophy, and induce degeneration of the germinal epithelial lining of the seminiferous tubules resulting in decreased spermatogenesis ... spermatogenesis , testicular atrophy, and ovarian dysfunction [Lee et al., 1985; Ellis et al., 1979; Lee et al., 1978 cited in USATHAMA, 1991a]. The

  16. Class VIIIA Materiel: What Problems Were Encountered Transiting OIF Air Transshipment Nodes

    DTIC Science & Technology

    2007-03-01

    LMI (Col ret). “Medical Logistics and Homeland Security,” briefing. Leedy , Paul D. and Jeanne Ellis Ormrod . Practical Research: Planning and...measures a characteristic that cannot be directly observed” ( Leedy , 2005). Internal validity allows the researcher to show causal relationships within...repeatedly, as long as the case does not change ( Leedy , 2005). 3. Prepare to collect the data When accomplishing case studies, it is normal for the

  17. Metrology for Information Technology

    DTIC Science & Technology

    1997-05-01

    unit. As Ellis states, "If we must speak of counting as a measuring procedure, it is unique among all measuring procedures." Carnap claims that...actual state of the world. However, probability is understood in another sense: as "degree of confirmation." Carnap ° claims that the term...Rudolf Carnap , Philosophical Foundations of Physics. Basic Books: New York. 1996. 6. Karel Berka, Measurement: Its Concepts, Theories and Problems. D

  18. Anisotropic Bianchi types VIII and IX locally rotationally symmetric cosmologies

    SciTech Connect

    Assad, M.J.D.; Soares, I.D.

    1983-10-15

    We present a class of exact cosmological solutions of Einstein-Maxwell equations, which are anisotropic and spatially homogeneous of Bianchi types VIII and IX, and class IIIb in the Stewart-Ellis classification of locally rotationally symmetric models. If we take the electromagnetic field equal to zero, a class of Bianchi types VIII/IX spatially homogeneous anisotropic cosmological solutions with perfect fluid is obtained.

  19. A Research Program in Computer Technology

    DTIC Science & Technology

    1975-09-01

    Moore Vernon W. Reynolds Dale S. Russell Support Staff: Ralph W. Caldwell Wanda N. Canillas Dale M. Chase Oralio E. Carza Delia A. Heilig Kyle P. Lemmons...Raymond L Mason Danny Cohen Marion McKinley Jr. Martin,’. Cohen William H. Moore E. Randolph Cole Vernon W. Reynolds Stephen D. Crocker Dale S. Russell...Ronald L. Currier Thomas 0. Ellis Support Staff: Robert Blechen Lawrence M. Fagar, Ralph W. Caldwell Louis Gallenson Wanda N. Canillas Joel Coldbe’rg

  20. Capabilities and Competencies in Humanitarian Operations

    DTIC Science & Technology

    2012-06-18

    rpfkbpp=C=mr_if`=mlif`v= = - 2 - k^s^i=mlpqdo^ar^qb=p`elli= (USCG) cutter Forward was diverted from its patrolling duties in the Caribbean to Port ...the Destruction of the Port at Port -au-Prince, Haiti, Captured by the U.S. Coast Guard Cutter Forward in the Aftermath of the January 12, 2010...the similarities and differences between the two (Jahre, Jensen, & Listou, 2009; Kovács & Tatham, 2009; Pettit & Beresford, 2005). Specifically

  1. Sound Evidence: The Missing Piece of the Jigsaw in Formulaic Language Research

    ERIC Educational Resources Information Center

    Lin, Phoebe M. S.

    2012-01-01

    With the ever increasing number of studies on formulaic language, we are beginning to learn more about the processing of formulaic language (e.g. Ellis et al. 2008; Siyanova et al. 2011), its use in speech (e.g. Aijmer 1996; Wood 2012) and writing (e.g. Hyland 2008a, 2008b) and its application in natural language processing (e.g. Tschichold 2000).…

  2. The U.S. Navy in Operation Overlord Under the Command of Rear Admiral Alan G. Kirk

    DTIC Science & Technology

    1994-05-19

    doubled soon after the arrival of Eisenhower and Montgomery, Bradely assigned two veteran infantry divisions to lead the assault. Bradley planned to send a...213; and Keegan, Second World War, pp. 375-77. 179 14. Ellis, Victory in the-West, p. 17; 15. Alfred Chandler, ed., The Papers of Dwight David ...Kirk Mss, NHC. 3. David Brown, "Operation Neptune, The Normandy Invasion: 6 dune to 3 July 1944," July 1993, Naval Historical Branch, Ministry of

  3. Galaxies at High Redshift

    NASA Astrophysics Data System (ADS)

    Pérez-Fournon, I.; Balcells, M.; Moreno-Insertis, F.; Sánchez, F.

    2010-08-01

    Participants; Group photograph; Preface; Acknowledgements; 1. Galaxy formation and evolution: recent progress R. Ellis; 2. Galaxies at high redshift M. Dickinson; 3. High-redshift galaxies: the far-infrared and sub-millimeter view A. Franceschini; 4. Quasar absorption lines J. Bechtold; 5. Stellar population synthesis models at low and high redshift G. Bruzual A.; 6. Elliptical galaxies K. C. Freeman; 7. Disk galaxies K. C. Freeman; 8. Dark matter in disk galaxies K. C. Freeman.

  4. Managing the Service Supply Chain in the Department of Defense: Opportunities and Challenges

    DTIC Science & Technology

    2006-12-30

    NPS Acquisition Research Program Attn: James B. Greene , RADM, USN, (Ret) Acquisition Chair Graduate School of Business and Public Policy Naval...mlif`v - iii - k^s^i=mlpqdo^ar^qb=p`elli= Acknowledgements The authors are greatly thankful to RADM Jim Greene , USN (Ret), the NPS Acquisition...comprehensive collections of readings such as Bowen, Chase & Cummings (1990), Brown, Gummesson, Edvardsson & Gustavsson (1991), and Lovelock (1992

  5. Africa’s Information Revolution: Implications for Crime, Policing, and Citizen Security

    DTIC Science & Technology

    2013-11-01

    entrepreneurs, investors, and technologists. Nokia partnered with CcHub in 2012 to launch the Growth Academy, an incubator for mobile technology...Technology & Innovation Trajectory (World Association for Sustainable Development (WASD), February 2010). 56 Elly Okutoyi, “ Nokia Partners with Nigeria’s...CcHub to Launch a Mobile Software Accelerator Academy,” The Next Web (TNW), May 28, 2012, available at <http://thenextweb.com/africa/2012/05/28/ nokia

  6. Infrared Spectroscopic Imaging for Prostate Pathology Practice

    DTIC Science & Technology

    2008-03-01

    J Biomed Opt 4: 14 –21 13. Kidder LH, Kalasinsky VF , Luke JL, Levin IW, Lewis EN (1997) Nat Medicine 3:235–237 14 . Ellis DI, Goodacre R (2006) Analyst...TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) 14 -03-2008 2. REPORT TYPE Annual 3. DATES COVERED (From - To) 15 FEB 2007 - 14 FEB 2008 4...DISTRIBUTION / AVAILABILITY STATEMENT Approved for public release; distribution unlimited 13. SUPPLEMENTARY NOTES 14 . ABSTRACT The report summarizes

  7. A Department of Homeland Security Reserves (DHS-R): Simultaneously Protecting the Homeland While Alleviating the Increased DoD Role in Homeland Defense and Security

    DTIC Science & Technology

    2007-12-01

    tribuneedition.html accessed on May 12, 2007. 21 Personal Interview with Ellis Stanley, General Manager- Emergency Preparedness Department, City ...California Office of Homeland Security, the Los Angeles City and County office of Emergency Preparedness, the FEMA/USNORTHCOM liaison, Citizen Corps...Preparedness for LA City , who guided my research. I also met with Mr. Bill Carwile of FEMA and Mr. Charles Adams of DHS, whose homeland security

  8. The Impact of a Common MDM2 SNP on the Sensitivity of Breast Cancer to Treatment

    DTIC Science & Technology

    2011-06-01

    Univariate and multivariate survival analysis was carried out using Cox’s proportional hazard regression model. Multivariate analysis was used to...found to have predictive value in the ER+ subset may be explained by higher biologic activity of MDM2 in estrogen responsive tumors. Numerous...Garcia MA, Green AR, Reis-Filho JS, Ellis IO: The biological , clinical and prognostic implications of p53 transcriptional pathways in breast cancers

  9. An Assessment of Fecal Coliform Bacteria in Cruise Ship Wastewater Discharge

    DTIC Science & Technology

    2003-09-01

    An Assessment of Fecal Coliform Bacteria in Cruise Ship Wastewater Discharge Charles D. McGee Orange County Sanitation District* 10844 Ellis...Alaska Cruise Ship Initiative in 1999. This initiative required investigation, understanding and oversight of discharges from large cruise ships...into the waters of Alaska. As part of the overall assessment of impacts from cruise ship waste discharges on the environment, a Science Advisory

  10. Light curves of light rays passing through a wormhole

    NASA Astrophysics Data System (ADS)

    Tsukamoto, Naoki; Harada, Tomohiro

    2017-01-01

    Gravitational lensing is a good probe into the topological structure of dark gravitating celestial objects. In this paper, we investigate the light curve of a light ray that passes through the throat of an Ellis wormhole, the simplest example of traversable wormholes. The method developed here is also applicable to other traversable wormholes. To study whether the light curve of a light ray that passes through a wormhole throat is distinguishable from that which does not, we also calculate light curves without the passage of a throat for an Ellis wormhole, a Schwarzschild black hole, and an ultrastatic wormhole with the spatial geometry identical to that of the Schwarzschild black hole in the following two cases: (i) "microlensing," where the source, lens, and observer are almost aligned in this order and the light ray starts at the source, refracts in the weak gravitational field of the lens with a small deflection angle, and reaches the observer; and (ii) "retrolensing," where the source, observer, and lens are almost aligned in this order, and the light ray starts at the source, refracts in the vicinity of the light sphere of the lens with a deflection angle very close to π , and reaches the observer. We find that the light curve of the light ray that passes through the throat of the Ellis wormhole is clearly distinguishable from that by the microlensing but not from that by the retrolensing. This is because the light curve of a light ray that passes by a light sphere of a lens with a large deflection angle has common characters, irrespective of the details of the lens object. This implies that the light curves of the light rays that pass through the throat of more general traversable wormholes are qualitatively the same as that of the Ellis wormhole.

  11. Medical Surveillance Monthly Report (MSMR). Volume 21, Number 01, January 2014

    DTIC Science & Technology

    2014-01-01

    progressive elimination in coun- tries where feasible. Malaria surveillance and control in the Republic of Korea bring to light the key role that...Melvin Susan Ellis/bugwood.org JANUARY 2014 Volume 21 Number 01 P A G E 2 Editorial: the military and its potential role in malaria elimination P A...Potential Role in Malaria Elimination Editorial James F. Cummings, MD (COL, USA) tended to wane in settings of infrequent malaria transmission

  12. Factors in Human-Computer Interface Design (A Pilot Study).

    DTIC Science & Technology

    1994-12-01

    classmates, Captain John Ellis, Captain Karen Cook, Captain Connie Hutchinson, Captain Alison McCoy, Captain Matt Pirko, Captain Brian Brown, Captain Susan...available, use the INFO? command to retrieve it. You can then use the INFO command again for specific topics. One handy feature in LISTSERV is that you can...then use the INFO command again for specific topics. One handy feature in LISTSERV is that you can send multiple commands in one message. Make sure to

  13. Survey and Assessment of the Cultural Resources, Toronto Lake Project.

    DTIC Science & Technology

    1981-01-01

    localities. Survey data will probably only allow possible reconstruc- tions of former stream channels and attendant gallery forest zones. 3) Assessing the...Williamson Site) 1550 B.C+100 & 1650 B.C+190 Projectile points of the Lange (Bell 1958: 36), Afton (Bell 1958: 6), and Ellis (Bell 1960: 32) styles...mammalian, aquatic, and plant resources clustered within the forested floodplains of streams allowed the peoples practicing Woodland culture to settle in

  14. The 1980 Archeological Investigations at the Big Hill Lake, Kansas.

    DTIC Science & Technology

    1980-01-01

    rodents and other mammals such as coyotes, raccoons, bobcats, opossums, etc. The bottomland forests are also represented on a small scale in the Big... forests are adjacent to Big Hill creek and its feeder tributaries. These streams, some intermittent, provide suitable habitation for many groups of...points recovered from the areas near the hearths have suggested Preceramic cultural affiliations and have been identified as Afton , Ellis, Lange

  15. Survey and Assessment of the Cultural Resources, Marion Lake Project.

    DTIC Science & Technology

    1981-01-01

    rabbit, and badger. The forested regions provided shelter and subsistence for white-tail and mule deer, black bear, cougar, lynx, red and grey fox...1958:36), Afton (Bell 1958:6), and Ellis (Bell 1960:32) styles may relate to some of these components. A fuller, but undated, late Archaic occupation...Commission. Both the wild life preserve and public areas provide habitat for geese, pheasants, and quail. The main aquatic species represented are

  16. A Study of Research and Development Contract Requirements and Their Growth.

    DTIC Science & Technology

    1979-05-01

    practices were dominant in the industry , and the interfaces low in number and com- plexity, assembly was accomplished with minimal problem. As airplanes...contractor for the program on the grounds that no single industrial organization possessed the nec- essary range of skills and over-all capability required to...Reference Willis Ellis’ book A Source Book of Gestalt Psychology (Bibliography number 11). 23. For a discussion of the basic research sources and methods

  17. Macrolide Antibiotics Improve Phagocytic Capacity and Reduce Inflammation In Sulfur Mustard-Exposed Monocytes

    DTIC Science & Technology

    2008-12-01

    improving SM inhalation injuries. In this study, the effects of four FDA- approved macrolide antibiotics, i.e., azithromycin , clarithromycin , erythromycin...from Sigma (St. Louis, MO). Azithromycin and clarithromycin were kindly provided by William Ellis of the Department of Chemical Information, WRAIR...0.001). Treatment with 10 µM of azithromycin , clarithromycin , erythromycin, or roxithromycin increased phagocytotic cells to 64.5%, 63.4%, 62.0

  18. Homosexuals and the U.S. Military: Current Issues

    DTIC Science & Technology

    2009-07-22

    FORSCOM Regulation 500-3-3, Volume III , Reserve Component Unit Commander’s Handbook, Fort McPherson, Georgia, 15 July 1999: 27, 33. 30 See Burrelli...Chief Judge J. Harvie Wilkinson III stressed Congress’ “plenary control” of the military and the “deference” owed both the Executive and Legislative...the Fourth Circuit relied on Thomasson to affirm a ruling by federal District Judge Ellis in Thorne v. U.S. Department of Defense.52 After reviewing

  19. Homosexuals and the U.S. Military: Current Issues

    DTIC Science & Technology

    2008-07-18

    homosexuality.” 30 U.S. Army, FORSCOM Mobilization and Deployment Planning System (FORMDEPS), FORSCOM Regulation 500-3-3, Volume III , Reserve Component Unit...for the nine-member majority in Thomasson v. Perry,51 Chief Judge J. Harvie Wilkinson III stressed Congress’ “plenary control” of the military and the...Thomasson to affirm a ruling by federal District Judge Ellis in Thorne v. U.S. Department of Defense.53 After reviewing the record in eight other

  20. The Hierarchical Database Decomposition Approach to Database Concurrency Control.

    DTIC Science & Technology

    1984-12-01

    access synchron- ization in a database system. The report develops the theory that supports the correctness of such analysis and algorithms. An...IiThe thesis develops the theory that supports the correctness of such analy- sis and algorithms. An implementation scheme for the proposed algorithm, the...encouraged development of many new algorithms. <For example, Ellis77, Lamport78, Rosenkrantz78, Thomas79, Bernstein8l.> A survey and comparison of theories