A science data gateway for environmental management: A SCIENCE DATA GATEWAY FOR ENVIRONMENTAL MANAGEMENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Agarwal, Deborah A.; Faybishenko, Boris; Freedman, Vicky L.

Science data gateways are effective in providing complex science data collections to the world-wide user communities. In this paper we describe a gateway for the Advanced Simulation Capability for Environmental Management (ASCEM) framework. Built on top of established web service technologies, the ASCEM data gateway is specifically designed for environmental modeling applications. Its key distinguishing features include: (1) handling of complex spatiotemporal data, (2) offering a variety of selective data access mechanisms, (3) providing state of the art plotting and visualization of spatiotemporal data records, and (4) integrating seamlessly with a distributed workflow system using a RESTful interface. ASCEM projectmore » scientists have been using this data gateway since 2011.« less

Space Station Freedom Gateway to the Future

NASA Technical Reports Server (NTRS)

1992-01-01

The first inhabited outpost on the frontier of space will be a place to live, work, and discover. Experiments conducted on Freedom will advance scientific knowledge about our world, our environment, and ourselves. We will learn how to adapt to the space environment and to build and operate new spacecraft with destinations far beyond Earth, continuing the tradition of exploration that began with a journey to the Moon. What we learn from living and working on Freedom will strengthen our expertise in science and engineering, promote national research and development initiatives and inspire another generation of Americans to push forward and onward. On the eve of the 21st century, Space Station Freedom will be our gateway to the future. This material covers gateways to space, research, discovery, utilization, benefits, and NASA.

Multi-Modal Traveler Information System - Gateway Phased Implementation Plan

DOT National Transportation Integrated Search

1997-11-25

The purpose of this working paper is to provide the main concepts and elements that need to be addressed in the overall implementation of the Gateway, both the Initial Phase and the Ultimate Phase. This working paper addresses these concepts and elem...

Analytic Patch Configuration (APC) gateway version 1.0 user's guide

NASA Technical Reports Server (NTRS)

Bingel, Bradford D.

1990-01-01

The Analytic Patch Configuration (APC) is an interactive software tool which translates aircraft configuration geometry files from one format into another. This initial release of the APC Gateway accommodates six formats: the four accepted APC formats (89f, 89fd, 89u, and 89ud), the PATRAN 2.x phase 1 neutral file format, and the Integrated Aerodynamic Analysis System (IAAS) General Geometry (GG) format. Written in ANSI FORTRAN 77 and completely self-contained, the APC Gateway is very portable and was already installed on CDC/NOS, VAX/VMS, SUN, SGI/IRIS, CONVEX, and GRAY hosts.

How leaky is the health career pipeline? Minority student achievement in college gateway courses.

PubMed

Alexander, Charles; Chen, Eric; Grumbach, Kevin

2009-06-01

To determine whether underrepresented minority (URM) students receive lower grades than do non-URM students in college prehealth gateway courses; the extent to which lower grade performance might be explained by the differences in precollege academic achievement; and whether URM students are less likely than non-URM students to persist in completing at least four gateway courses. Administrative data were obtained from six California colleges on 15,000 college students who matriculated in the 1999-2000 or 2000-2001 academic years and enrolled in at least one college course required for application to medical or dental school ("gateway" courses). Students were compared across ethnic groups in gateway course grade performance and persistence in completing at least four gateway courses, using regression methods to control for students' college admission test scores and caliber of high school attended. URM students received significantly lower grades on average in gateway courses than did white students. This gap persisted after adjusting for measures of prior academic performance. However, URM students were nearly as likely as white students to persist in completing at least four gateway courses. After accounting for the lower grades of URM students in their initial classes, URM students were more likely than white students to complete four or more gateway courses. URM students experienced academic challenges, but many persist in their prehealth courses despite these challenges. Interventions at the college level to support URM student performance in gateway courses are particularly important for increasing the diversity of medical and dental schools.

High-Performance Satellite/Terrestrial-Network Gateway

NASA Technical Reports Server (NTRS)

Beering, David R.

2005-01-01

A gateway has been developed to enable digital communication between (1) the high-rate receiving equipment at NASA's White Sands complex and (2) a standard terrestrial digital communication network at data rates up to 622 Mb/s. The design of this gateway can also be adapted for use in commercial Earth/satellite and digital communication networks, and in terrestrial digital communication networks that include wireless subnetworks. Gateway as used here signifies an electronic circuit that serves as an interface between two electronic communication networks so that a computer (or other terminal) on one network can communicate with a terminal on the other network. The connection between this gateway and the high-rate receiving equipment is made via a synchronous serial data interface at the emitter-coupled-logic (ECL) level. The connection between this gateway and a standard asynchronous transfer mode (ATM) terrestrial communication network is made via a standard user network interface with a synchronous optical network (SONET) connector. The gateway contains circuitry that performs the conversion between the ECL and SONET interfaces. The data rate of the SONET interface can be either 155.52 or 622.08 Mb/s. The gateway derives its clock signal from a satellite modem in the high-rate receiving equipment and, hence, is agile in the sense that it adapts to the data rate of the serial interface.

Gateway to the Future

ERIC Educational Resources Information Center

DiJulio, Betsy

2012-01-01

"Gateway to the Future" pairs a painting of a gateway constructed from children's building blocks with an ink drawing of a personal symbol on a collaged background. The main objective of this lesson is to create a metaphoric artwork about moving from the present through a symbolic portal to the future. So, space--foreground, middle ground, and…

Deep Space Gateway Science Opportunities

NASA Astrophysics Data System (ADS)

Quincy, C. D.; Charles, J. B.; Hamill, D. L.; Sun, S. C.

2018-02-01

Life sciences see the Deep Space Gateway as an opportunity to investigate biological organisms in a unique environment that cannot be replicated in Earth-based labs or on LEO platforms. The needed capabilities must be built into the Gateway facility.

Data-intensive science gateway for rock physicists and volcanologists.

NASA Astrophysics Data System (ADS)

Filgueira, Rosa; Atkinson, Malcom; Bell, Andrew; Main, Ian; Boon, Steve; Meredith, Philp; Kilburn, Christopher

2014-05-01

Scientists have always shared data and mathematical models of the phenomena they study. Rock physics and Volcanology, as well as other solid-Earth sciences, have increasingly used Internet communications and computational renditions of their models for this purpose over the last two decades. Here we consider how to organise rock physics and volcanology data to open up opportunities for sharing and comparing both experiment data from experiments, observations and model runs and analytic interpretations of these data. Our hypothesis is that if we facilitate productive information sharing across those communities by using a new science gateway, it will benefit the science. The proposed science gateway should make the first steps for making existing research practices easier and facilitate new research. It will achieve this by supporting three major functions: 1) sharing data from laboratories and observatories, experimental facilities and models; 2) sharing models of rock fracture and methods for analysing experimental data; and 3) supporting recurrent operational tasks, such as data collection and model application in real time. We report initial work in two projects (NERC EFFORT and NERC CREEP-2) and experience with an early web-accessible protytpe called EFFORT gateway, where we are implementing such information sharing services for those projects. 1. Sharing data: In EFFORT gateway, we are working on several facilities for sharing data: *Upload data: We have designed and developed a new adaptive data transfer java tool called FAST (Flexible Automated Streaming Transfer) to upload experimental data and metadata periodically from laboratories to our repository. *Visualisation: As data are deposited in the repository, a visualisation of the accumulated data is made available for display in the Web portal. *Metadata and catalogues: The gateway uses a repository to hold all the data and a catalogue to hold all the corresponding metadata. 2. Sharing models and methods

BSV Gateway Description

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deshpande, Alina

Los Alamos National Laboratory (LANL) is part of that worldwide team and has been developing state of the art information systems to aid the global health community. For instance, in 2014 LANL announced the release of the LANL Biosurveillance (BSV) Gateway. The site provides information about ongoing biosurveillance research projects and capabilities at LANL, and provides access to a host of LANL-developed biosurveillance tools and resources. We are seeking feedback on this gateway and would like to ask interested folk to offer comments and suggestions after they have perused the BSV website.

Gateway design specification for fiber optic local area networks

NASA Technical Reports Server (NTRS)

1985-01-01

This is a Design Specification for a gateway to interconnect fiber optic local area networks (LAN's). The internetworking protocols for a gateway device that will interconnect multiple local area networks are defined. This specification serves as input for preparation of detailed design specifications for the hardware and software of a gateway device. General characteristics to be incorporated in the gateway such as node address mapping, packet fragmentation, and gateway routing features are described.

Development of ISO connection-oriented/correctionless gateways

NASA Technical Reports Server (NTRS)

Landweber, Lawrence H.

1991-01-01

The project had two goals, establishment of a gateway between French and U.S. academic networks and studies of issues related to the development of ISO connection-oriented/connectionless (CO/CL) gateways. The first component involved installation of a 56K bps line between Princeton Univ. and INRIA in France. The end-points of these lines were connected by Vitalink link level bridges. The Princeton end was then connected to the NSFNET via the John Von Neumann Supercomputer Center. The French end was connected to Transpac, the French X.25 public data network and to the French IP research internet. U.S. users may communicate with users of the French internet by e-mail and may access computational and data resources in France by use of remote login and file transfer. The connection to Transpac enables U.S. users to access the SIMBAD astronomical database outside of Paris. Access to this database from the U.S. can be via TCP/IP or DECNET (via a DECNET to TCP/IP gateway) protocols utilizing a TCP/IP to X.25 gateway developed and operated by INRIA. The second component of the project involved experiments aimed at understanding the issues involved is ISO CO/CL gateways. An experimental gateway was developed at Wisconsin and a preliminary report was prepared. Because of the need to devote most resources to the first component of the project, work in this area did not go beyond development of a prototype gateway.

47 CFR 10.320 - Provider alert gateway requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... must be identified by a unique IP address or domain name. (b) Authentication and validation. The CMS... alert gateway if a validation fails. (c) Security. The CMS provider gateway must support standardized IP... CMSP Name Unique identification of CMSP. CMSP gateway Address IP address or Domain Name Alternate IP...

ADDOSS: Autonomously Deployed Deep-ocean Seismic System - Communications Gateway for Ocean Observatories

NASA Astrophysics Data System (ADS)

Laske, Gabi; Berger, Jon; Orcutt, John; Babcock, Jeff

2014-05-01

We describe an autonomously deployable, communications gateway designed to provide long-term and near real-time data from ocean observatories. The key features of this new system are its abilities to telemeter sensor data from the seafloor to shore without cables or moorings, and to be deployed without a ship, thereby greatly reducing life-cycle costs. The free-floating surface communications gateway utilizes a Liquid Robotics wave glider comprising a surfboard-sized float towed by a tethered, submerged glider, which converts wave motion into thrust. For navigation, the wave glider is equipped with a small computer, a GPS receiver, a rudder, solar panels and batteries, and an Iridium satellite modem. Acoustic communications connect the subsea instruments and the surface gateway while communications between the gateway and land are provided by the Iridium satellite constellation. Wave gliders have demonstrated trans-oceanic range and long-term station keeping capabilities. The acoustics communications package is mounted in a shallow tow body which utilizes a WHOI micro modem and a Benthos low frequency, directional transducer. A matching modem and transducer is mounted on the ocean bottom package. Tests of the surface gateway in 4350 m of water demonstrated an acoustic efficiency of approximately 396 bits/J. For example, it has the ability to send 4 channels of compressed, 1 sample per second data from the ocean bottom to the gateway with an average power draw of approximately 0.15 W and a latency of less than 3 minutes. This gateway is used to send near real-time data from a broadband ocean bottom seismic observatory, first during short week-to-months long test deployments but will ultimately be designed for a two-year operational life. Such data from presently unobserved oceanic areas are critical for both national and international agencies in monitoring and characterizing earthquakes, tsunamis, and nuclear explosions. We present initial results from a two short

High-performance parallel interface to synchronous optical network gateway

DOEpatents

St. John, Wallace B.; DuBois, David H.

1996-01-01

A system of sending and receiving gateways interconnects high speed data interfaces, e.g., HIPPI interfaces, through fiber optic links, e.g., a SONET network. An electronic stripe distributor distributes bytes of data from a first interface at the sending gateway onto parallel fiber optics of the fiber optic link to form transmitted data. An electronic stripe collector receives the transmitted data on the parallel fiber optics and reforms the data into a format effective for input to a second interface at the receiving gateway. Preferably, an error correcting syndrome is constructed at the sending gateway and sent with a data frame so that transmission errors can be detected and corrected in a real-time basis. Since the high speed data interface operates faster than any of the fiber optic links the transmission rate must be adapted to match the available number of fiber optic links so the sending and receiving gateways monitor the availability of fiber links and adjust the data throughput accordingly. In another aspect, the receiving gateway must have sufficient available buffer capacity to accept an incoming data frame. A credit-based flow control system provides for continuously updating the sending gateway on the available buffer capacity at the receiving gateway.

High-performance parallel interface to synchronous optical network gateway

DOEpatents

St. John, W.B.; DuBois, D.H.

1996-12-03

Disclosed is a system of sending and receiving gateways interconnects high speed data interfaces, e.g., HIPPI interfaces, through fiber optic links, e.g., a SONET network. An electronic stripe distributor distributes bytes of data from a first interface at the sending gateway onto parallel fiber optics of the fiber optic link to form transmitted data. An electronic stripe collector receives the transmitted data on the parallel fiber optics and reforms the data into a format effective for input to a second interface at the receiving gateway. Preferably, an error correcting syndrome is constructed at the sending gateway and sent with a data frame so that transmission errors can be detected and corrected in a real-time basis. Since the high speed data interface operates faster than any of the fiber optic links the transmission rate must be adapted to match the available number of fiber optic links so the sending and receiving gateways monitor the availability of fiber links and adjust the data throughput accordingly. In another aspect, the receiving gateway must have sufficient available buffer capacity to accept an incoming data frame. A credit-based flow control system provides for continuously updating the sending gateway on the available buffer capacity at the receiving gateway. 7 figs.

GATEWAY Report Brief: Exterior Lighting at Princeton University

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

Summary of GATEWAY report focuses on four exterior solid-state lighting projects that have been completed at Princeton since 2008, when the University adopted a comprehensive sustainability plan. Through these initial projects – which include a parking garage, a pedestrian path, and two parking lot installations – the school’s facilities engineering staff learned important lessons about SSL technology and gained experience in dealing with the rapidly changing landscape of lighting manufacturers and their suppliers.

A Technology-Enriched Active Learning Space for a New Gateway Education Programme in Hong Kong: A Platform for Nurturing Student Innovations

ERIC Educational Resources Information Center

Chiu, Pit Ho Patrio

2016-01-01

A Gateway Education Programme is established in Hong Kong that aims to broaden students' interdisciplinary knowledge and nurture student innovations under the Discovery-enriched Curriculum. To support the initiative, a novel idea was proposed for the creation of a Gateway Education Laboratory (GE Lab) with a highly configurable layout equipped…

Gateways Revitalization Strategy

EPA Pesticide Factsheets

Lancaster County, PA, created the Gateway plan to reconnect various areas of the community, revitalize the economic base, improve and build on infrastructure and public/private partnerships, and retain current residents.

The Effectiveness of Gateway Communications in Anti-Marijuana Campaigns

PubMed Central

YZER, MARCO C.; CAPPELLA, JOSEPH N.; FISHBEIN, MARTIN; HORNIK, ROBERT; AHERN, R. KIRKLAND

2014-01-01

Successful anti-marijuana messages can be hypothesized to have two types of effects, namely persuasion effects, that is, a change in people’s beliefs about using marijuana, and priming effects, that is, a strengthened correlation between beliefs and associated variables such as attitude and intention. This study examined different sets of anti-drug advertisements for persuasion and priming effects. The ads targeted the belief that marijuana is a gateway to stronger drugs, a belief that is often endorsed by campaign planning officials and health educators. A sample of 418 middle and high school students was randomly assigned to a control video or one of three series of ads, two of which included the gateway message in either an explicit or implicit way. Results did not support the use of the gateway belief in anti-marijuana interventions. Whereas no clear persuasion or priming effects were found for any of the ad sequences, there is some possibility that an explicit gateway argument may actually boomerang. In comparison to the control condition, adolescents in the explicit gateway condition tended to agree less with the gateway message and displayed weaker correlations between anti-marijuana beliefs and their attitude toward marijuana use. The results suggest that the gateway message should not be used in anti-drug interventions. PMID:12746037

From the Adam Smith Institute to the Zapatistas: An Internet Gateway to all Development Knowledge.

ERIC Educational Resources Information Center

Wilks, Alex

2002-01-01

Examines the World Bank Internet initiative, the Development Gateway. Describes the importance of the Bank as a knowledge bank and the threats posed by the Internet to its near monopoly of development thinking. Argues that the initiative reveals biases and misunderstandings in the World Bank's approach to knowledge for development. (CAJ)

47 CFR 10.310 - Federal alert gateway. [Reserved

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 1 2013-10-01 2013-10-01 false Federal alert gateway. [Reserved] 10.310 Section 10.310 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL WIRELESS EMERGENCY ALERTS System Architecture § 10.310 Federal alert gateway. [Reserved] ...

47 CFR 10.310 - Federal alert gateway. [Reserved

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 1 2014-10-01 2014-10-01 false Federal alert gateway. [Reserved] 10.310 Section 10.310 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL WIRELESS EMERGENCY ALERTS System Architecture § 10.310 Federal alert gateway. [Reserved] ...

HOSC DTN Gateway Test Report

NASA Technical Reports Server (NTRS)

Pitts, Robert Lee

2012-01-01

Goals of this activity: Test the Huntsville Operations Support Center (HOSC) Delay/Disruption Tolerant Networking (DTN) Gateway for operational use Current activity includes: (1) Test the Implementation of a new DTN2 gateway at the HOSC (2) Confirm integration of DTN nodes into the S-band uplink and Ku-band downlink of the ISS for limited use (3) Implement Aggregate Custody Signal to ISS platforms (4) Verify operational support for Colorado University (CU) onboard components (5) Verify ability to support Multi-Purpose End-To- End Robotic Operation Network (METERON) OpsCon-2

47 CFR 10.310 - Federal alert gateway. [Reserved

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Federal alert gateway. [Reserved] 10.310 Section 10.310 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM System Architecture § 10.310 Federal alert gateway. [Reserved] ...

47 CFR 10.310 - Federal alert gateway. [Reserved

Code of Federal Regulations, 2012 CFR

2012-10-01

... 47 Telecommunication 1 2012-10-01 2012-10-01 false Federal alert gateway. [Reserved] 10.310 Section 10.310 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM System Architecture § 10.310 Federal alert gateway. [Reserved] ...

47 CFR 10.310 - Federal alert gateway. [Reserved

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 1 2011-10-01 2011-10-01 false Federal alert gateway. [Reserved] 10.310 Section 10.310 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM System Architecture § 10.310 Federal alert gateway. [Reserved] ...

Science Gateways, Scientific Workflows and Open Community Software

NASA Astrophysics Data System (ADS)

Pierce, M. E.; Marru, S.

2014-12-01

Science gateways and scientific workflows occupy different ends of the spectrum of user-focused cyberinfrastructure. Gateways, sometimes called science portals, provide a way for enabling large numbers of users to take advantage of advanced computing resources (supercomputers, advanced storage systems, science clouds) by providing Web and desktop interfaces and supporting services. Scientific workflows, at the other end of the spectrum, support advanced usage of cyberinfrastructure that enable "power users" to undertake computational experiments that are not easily done through the usual mechanisms (managing simulations across multiple sites, for example). Despite these different target communities, gateways and workflows share many similarities and can potentially be accommodated by the same software system. For example, pipelines to process InSAR imagery sets or to datamine GPS time series data are workflows. The results and the ability to make downstream products may be made available through a gateway, and power users may want to provide their own custom pipelines. In this abstract, we discuss our efforts to build an open source software system, Apache Airavata, that can accommodate both gateway and workflow use cases. Our approach is general, and we have applied the software to problems in a number of scientific domains. In this talk, we discuss our applications to usage scenarios specific to earth science, focusing on earthquake physics examples drawn from the QuakSim.org and GeoGateway.org efforts. We also examine the role of the Apache Software Foundation's open community model as a way to build up common commmunity codes that do not depend upon a single "owner" to sustain. Pushing beyond open source software, we also see the need to provide gateways and workflow systems as cloud services. These services centralize operations, provide well-defined programming interfaces, scale elastically, and have global-scale fault tolerance. We discuss our work providing

47 CFR 10.320 - Provider alert gateway requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 1 2014-10-01 2014-10-01 false Provider alert gateway requirements. 10.320 Section 10.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL WIRELESS EMERGENCY ALERTS System Architecture § 10.320 Provider alert gateway requirements. This section specifies the functions...

47 CFR 10.320 - Provider alert gateway requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 1 2013-10-01 2013-10-01 false Provider alert gateway requirements. 10.320 Section 10.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL WIRELESS EMERGENCY ALERTS System Architecture § 10.320 Provider alert gateway requirements. This section specifies the functions...

47 CFR 10.320 - Provider alert gateway requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 47 Telecommunication 1 2012-10-01 2012-10-01 false Provider alert gateway requirements. 10.320 Section 10.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM System Architecture § 10.320 Provider alert gateway requirements. This section specifies the functions...

SEDAC information gateway plan V(1)

NASA Technical Reports Server (NTRS)

Chen, Robert S. (Compiler)

1995-01-01

This annual update of the Information Gateway Plan incorporates changes recommended by the Socioeconomic Data and Applications Center (SEDAC) User Working Group (UWG) and reflects comments and suggestions from users, collaborators, and the Contracting Officer Technical Representative (COTR). The Information Gateway Plan is a concise and specific plan that outlines SEDAC activities and services in support of the earth and social sciences and other user communities. The SEDAC Information Gateway effort is a primary means by which the Earth Observing System Data and Information System (EOSDIS) can link meaningfully with a broad range of social science data sources and users in ways that lead to tangible benefits to the American people. The SEDAC Information Gateway provides interdisciplinary access to socioeconomic and physical science data and information resources held by SEDAC and numerous other institutions and networks around the world. The Plan describes the areas of research of earth scientists and socioeconomic scientists where interchange of data and information is most needed. It sets guidelines for the continued development of SEDAC's directory of social science datasets and establishes priorities for efforts to make data held by SEDAC or accessible through SEDAC available to the user community. The Plan also describes the means by which the SEDAC user community can access information products specified by the SEDAC Data and Applications Development Plan (DADP). Among other major activities, SEDAC will continue to enhance and operate a directory capability, interoperable with the Global Change Master Directory, that provides the socioeconomic community with information about earth science products and the earth science research community with information about socioeconomic data. The Information Gateway also serves as a unique and powerful access pathway for a wide range of users and potential users of socioeconomic and earth science data, including

Open Smart Energy Gateway (OpenSEG)

DOE Office of Scientific and Technical Information (OSTI.GOV)

The Open Smart Energy Gateway (OpenSEG) aims to provide near-real time smart meter data to consumers without the delays or latencies associated with it being transported to the utility data center and then back to the consumer's application. To do this, the gateway queries the local Smart Meter to which it is bound to get energy consumption information at pre-defined intervals (minimum interval is 4 seconds). OpenSEG then stores the resulting data internally for retrieval by an external application.

Straits to Extinction. Integrated Magneto-Bio-Stratigraphy and Cyclostratigraphy Studies Reveal the Destructive Power of Marine Gateways

NASA Astrophysics Data System (ADS)

Palcu, D.; Simon, D.; da Silva, A. C.; Popov, S. V.; Golovina, L.; Krijgsman, W.

2016-12-01

The marine gateways are an important element in the geographic and paleogeographic architecture of oceans and seas. They influence the heat and chemical exchange between neighbouring water bodies, mixing or segregating them and influencing the climate and the ecosystems. In extreme configurations, they play a role in the onset of Salinity Crises and the formation of evaporites. However, detailed information on the sensitivity and functioning of gateways remains scarce as their geological records are poorly preserved. To counter the lack of reliable records our research focuses on the impact of the gateways on the adjacent seas. We studied marine sediments from basins that belonged to the Neogene system of seas and lakes of Eurasia (Paratethys). Integrated magneto-bio-stratigraphy and cyclostratigraphy studies in these basins have provided high-resolution correlations between the neighbouring seas within Paratethys, which, in turn, led to the identification of problematic gateway configurations. Here we focus on two such configurations: the setting that allows evaporite formation and the configuration that leads to extinction events. The gateway setting responsible for salinity crises not only leads to extinctions but also to the formation evaporites. We focus on the Badenian Salinity Crisis (BSC), an event that occurred between 13.8-13.3Ma, which is particularly interesting because it is a selective salinity crisis, happening only in some of the sub-basins of Paratethys. In this case, our initial evidence shows that the configuration requires multiple gateways that can produce water stratification and brine formation. The gateway configuration that triggers extinctions has been linked with the Badenian-Sarmatian Extinction Event (BSEE), placed at 12.65Ma. The event. that has completely destroyed the marine ecosystems of Central and Eastern Europe (with an extinction rate of 94%), has occurred in less than 10kyr and according to our numerical modelling results it

Neutron Science TeraGrid Gateway

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lynch, Vickie E; Chen, Meili; Cobb, John W

The unique contributions of the Neutron Science TeraGrid Gateway (NSTG) are the connection of national user facility instrument data sources to the integrated cyberinfrastructure of the National Science FoundationTeraGrid and the development of a neutron science gateway that allows neutron scientists to use TeraGrid resources to analyze their data, including comparison of experiment with simulation. The NSTG is working in close collaboration with the Spallation Neutron Source (SNS) at Oak Ridge as their principal facility partner. The SNS is a next-generation neutron source. It has completed construction at a cost of $1.4 billion and is ramping up operations. The SNSmore » will provide an order of magnitude greater flux than any previous facility in the world and will be available to all of the nation's scientists, independent of funding source, on a peer-reviewed merit basis. With this new capability, the neutron science community is facing orders of magnitude larger data sets and is at a critical point for data analysis and simulation. There is a recognized need for new ways to manage and analyze data to optimize both beam time and scientific output. The TeraGrid is providing new capabilities in the gateway for simulations using McStas and a fitting service on distributed TeraGrid resources to improved turnaround. NSTG staff are also exploring replicating experimental data in archival storage. As part of the SNS partnership, the NSTG provides access to gateway support, cyberinfrastructure outreach, community development, and user support for the neutron science community. This community includes not only SNS staff and users but extends to all the major worldwide neutron scattering centers.« less

Maximizing Gateway-Course Improvement by Making the Whole Greater than the Sum of the Parts

ERIC Educational Resources Information Center

Koch, Andrew K.; Prystowsky, Richard J.; Scinta, Tony

2017-01-01

Drawing on systems theory, this chapter uses two different institutional examples to demonstrate the benefits of combining gateway-course improvement initiatives with other student success efforts so that the combined approach makes the whole greater than the simple sum of the pieces.

PAST Gateways (Palaeo-Arctic Spatial and Temporal Gateways): Introduction and overview

NASA Astrophysics Data System (ADS)

Ó Cofaigh, Colm; Briner, Jason P.; Kirchner, Nina; Lucchi, Renata G.; Meyer, Hanno; Kaufman, Darrell S.

2016-09-01

This special issue relates to the Second International Conference of the PAST Gateways (Palaeo-Arctic Spatial and Temporal Gateways) network which was held in Trieste, Italy in 2014. Twenty five papers are included and they address topics under four main themes: (1) The growth and decay of Arctic ice sheets; (2) Arctic sea ice and palaeoceanography; (3) Terrestrial Arctic environments and permafrost change; and (4) Holocene Arctic environmental change. Geographically the focus is circum-Arctic; the special issue includes detailed regional studies from Greenland, Scandinavia, Russia, and Arctic North America and the adjoining seas, as well as a series of synthesis-type, review papers on Fennoscandian Ice Sheet deglaciation and Holocene Arctic palaeo-climate change. The methodologies employed are diverse and include marine sediment core and geophysical investigations, terrestrial glacial geology and geomorphology, isotopic analysis of ground ice, palaeo-ecological analysis of lacustrine and terrestrial sedimentary archives, geochronology and numerical ice sheet modeling.

Global Document Delivery, User Studies, and Service Evaluation: The Gateway Experience

ERIC Educational Resources Information Center

Miller, Rush; Xu, Hong; Zou, Xiuying

2008-01-01

This study examines user and service data from 2002-2006 at the East Asian Gateway Service for Chinese and Korean Academic Journal Publications (Gateway Service), the University of Pittsburgh. Descriptive statistical analysis reveals that the Gateway Service has been consistently playing the leading role in global document delivery service as well…

An integrated gateway for various PHDs in U-healthcare environments.

PubMed

Park, KeeHyun; Pak, JuGeon

2012-01-01

We propose an integrated gateway for various personal health devices (PHDs). This gateway receives measurements from various PHDs and conveys them to a remote monitoring server (MS). It provides two kinds of transmission modes: immediate transmission and integrated transmission. The former mode operates if a measurement exceeds a predetermined threshold or in the case of an emergency. In the latter mode, the gateway retains the measurements instead of forwarding them. When the reporting time comes, the gateway extracts all the stored measurements, integrates them into one message, and transmits the integrated message to the MS. Through this mechanism, the transmission overhead can be reduced. On the basis of the proposed gateway, we construct a u-healthcare system comprising an activity monitor, a medication dispenser, and a pulse oximeter. The evaluation results show that the size of separate messages from various PHDs is reduced through the integration process, and the process does not require much time; the integration time is negligible.

An Integrated Gateway for Various PHDs in U-Healthcare Environments

PubMed Central

Park, KeeHyun; Pak, JuGeon

2012-01-01

We propose an integrated gateway for various personal health devices (PHDs). This gateway receives measurements from various PHDs and conveys them to a remote monitoring server (MS). It provides two kinds of transmission modes: immediate transmission and integrated transmission. The former mode operates if a measurement exceeds a predetermined threshold or in the case of an emergency. In the latter mode, the gateway retains the measurements instead of forwarding them. When the reporting time comes, the gateway extracts all the stored measurements, integrates them into one message, and transmits the integrated message to the MS. Through this mechanism, the transmission overhead can be reduced. On the basis of the proposed gateway, we construct a u-healthcare system comprising an activity monitor, a medication dispenser, and a pulse oximeter. The evaluation results show that the size of separate messages from various PHDs is reduced through the integration process, and the process does not require much time; the integration time is negligible. PMID:22899891

Mentoring the Next Generation of Science Gateway Developers and Users

NASA Astrophysics Data System (ADS)

Hayden, L. B.; Jackson-Ward, F.

2016-12-01

The Science Gateway Institute (SGW-I) for the Democratization and Acceleration of Science was a SI2-SSE Collaborative Research conceptualization award funded by NSF in 2012. From 2012 through 2015, we engaged interested members of the science and engineering community in a planning process for a Science Gateway Community Institute (SGCI). Science Gateways provide Web interfaces to some of the most sophisticated cyberinfrastructure resources. They interact with remotely executing science applications on supercomputers, they connect to remote scientific data collections, instruments and sensor streams, and support large collaborations. Gateways allow scientists to concentrate on the most challenging science problems while underlying components such as computing architectures and interfaces to data collection changes. The goal of our institute was to provide coordinating activities across the National Science Foundation, eventually providing services more broadly to projects funded by other agencies. SGW-I has succeeded in identifying two underrepresented communities of future gateway designers and users. The Association of Computer and Information Science/Engineering Departments at Minority Institutions (ADMI) was identified as a source of future gateway designers. The National Organization for the Professional Advancement of Black Chemists and Chemical Engineers (NOBCChE) was identified as a community of future science gateway users. SGW-I efforts to engage NOBCChE and ADMI faculty and students in SGW-I are now woven into the workforce development component of SGCI. SGCI (ScienceGateways.org ) is a collaboration of six universities, led by San Diego Supercomputer Center. The workforce development component is led by Elizabeth City State University (ECSU). ECSU efforts focus is on: Produce a model of engagement; Integration of research into education; and Mentoring of students while aggressively addressing diversity. This paper documents the outcome of the SGW

Remote Sensing Information Gateway

EPA Pesticide Factsheets

Remote Sensing Information Gateway, a tool that allows scientists, researchers and decision makers to access a variety of multi-terabyte, environmental datasets and to subset the data and obtain only needed variables, greatly improving the download time.

Mapping, monitoring, and modeling Western Gateway Community landscape dynamics

USGS Publications Warehouse

Hester, David J.

2013-01-01

Federal public lands in the western United States are becoming increasingly surrounded by Gateway Communities. These communities are undergoing landscape change due to population growth, economic growth, and the resulting land-use development. Socioeconomic, demographic, and land-use changes in Gateway Communities are often perceived as threats to Federal land resources, natural amenities, cultural resources, and recreational opportunities. However, land-surface disturbances on Federal public lands, such as conventional and alternative energy development (which impact surrounding Gateway Communities), are also environmental and societal issues that Federal land and adjacent regional community planners need to consider in their long-range land-use planning.

A Robotic Communications Gateway for Ocean Observations

NASA Astrophysics Data System (ADS)

Orcutt, J. A.; Berger, J.; Laske, G.; Babcock, J.

2015-12-01

We describe a new technology that can provide real-time telemetry of sensor data from the ocean bottom. The breakthrough technology that makes this system possible is an autonomous surface vehicle called the Wave Glider developed by Liquid Robotics, Inc. of Sunnyvale, CA., which harvests wave and solar energy for motive and electrical power. The free-floating surface communications gateway uses a Liquid Robotics wave glider comprising a surfboard-sized float towed by a tethered, submerged glider, which converts wave motion into thrust. For navigation, the wave glider is equipped with a small computer, a GPS receiver, a rudder, solar panels and batteries, and an Iridium satellite modem. Acoustic communications connect the subsea instruments and the surface gateway while communications between the gateway and land are provided by the Iridium satellite constellation. Wave gliders have demonstrated trans-oceanic range and long-term station keeping capabilities. The topside acoustics communications package is mounted in a shallow tow body, which uses a WHOI micro modem and a Benthos low frequency, directional transducer. A matching bottom side modem and transducer are mounted on the ocean bottom package. Tests of the surface gateway in 4000 m of water demonstrated an acoustic efficiency of approximately 256 bits/J. For example, it has the ability to send four channels of compressed, one sample per second data from the ocean bottom to the gateway with an average power draw of approximately 0.36 W and a latency of about three minutes. This gateway is used to send near-real-time data from a broadband ocean bottom seismic observatory; we are presently designing and constructing a seafloor package with a two-year operational life. We have found that for frequencies f where f<10mHz, 35mHz < f < 120mHz and f>~3Hz, the vertical component, seafloor system noise characteristics are generally superior to similar observatories on land. Increasing the density of these stations over

NASA gateway requirements analysis

NASA Technical Reports Server (NTRS)

Duncan, Denise R.; Doby, John S.; Shockley, Cynthia W.

1991-01-01

NASA devotes approximately 40 percent of its budget to R&D. Twelve NASA Research Centers and their contractors conduct this R&D, which ranges across many disciplines and is fueled by information about previous endeavors. Locating the right information is crucial. While NASA researchers use peer contacts as their primary source of scientific and technical information (STI), on-line bibliographic data bases - both Government-owned and commercial - are also frequently consulted. Once identified, the STI must be delivered in a usable format. This report assesses the appropriateness of developing an intelligent gateway interface for the NASA R&D community as a means of obtaining improved access to relevant STI resources outside of NASA's Remote Console (RECON) on-line bibliographic database. A study was conducted to determine (1) the information requirements of the R&D community, (2) the information sources to meet those requirements, and (3) ways of facilitating access to those information sources. Findings indicate that NASA researchers need more comprehensive STI coverage of disciplines not now represented in the RECON database. This augmented subject coverage should preferably be provided by both domestic and foreign STI sources. It was also found that NASA researchers frequently request rapid delivery of STI, in its original format. Finally, it was found that researchers need a better system for alerting them to recent developments in their areas of interest. A gateway that provides access to domestic and international information sources can also solve several shortcomings in the present STI delivery system. NASA should further test the practicality of a gateway as a mechanism for improved STI access.

Design of smart home gateway based on Wi-Fi and ZigBee

NASA Astrophysics Data System (ADS)

Li, Yang

2018-04-01

With the increasing demand for home lifestyle, the traditional smart home products have been unable to meet the needs of users. Aim at the complex wiring, high cost and difficult operation problems of traditional smart home system, this paper designs a home gateway for smart home system based on Wi-Fi and ZigBee. This paper first gives a smart home system architecture base on cloud server, Wi-Fi and ZigBee. This architecture enables users to access the smart home system remotely from Internet through the cloud server or through Wi-Fi at home. It also offers the flexibility and low cost of ZigBee wireless networking for home equipment. This paper analyzes the functional requirements of the home gateway, and designs a modular hardware architecture based on the RT5350 wireless gateway module and the CC2530 ZigBee coordinator module. Also designs the software of the home gateway, including the gateway master program and the ZigBee coordinator program. Finally, the smart home system and home gateway are tested in two kinds of network environments, internal network and external network. The test results show that the designed home gateway can meet the requirements, support remote and local access, support multi-user, support information security technology, and can timely report equipment status information.

Science gateways for semantic-web-based life science applications.

PubMed

Ardizzone, Valeria; Bruno, Riccardo; Calanducci, Antonio; Carrubba, Carla; Fargetta, Marco; Ingrà, Elisa; Inserra, Giuseppina; La Rocca, Giuseppe; Monforte, Salvatore; Pistagna, Fabrizio; Ricceri, Rita; Rotondo, Riccardo; Scardaci, Diego; Barbera, Roberto

2012-01-01

In this paper we present the architecture of a framework for building Science Gateways supporting official standards both for user authentication and authorization and for middleware-independent job and data management. Two use cases of the customization of the Science Gateway framework for Semantic-Web-based life science applications are also described.

Analysis of Random Drop for Gateway Congestion Control

DTIC Science & Technology

1989-11-01

effective congest)on control policies. Currently No Gateway Policy is used to relieve and signal congestion, which leads to unfair service to the...early application of the policy removes the pressure of congestion relief and allows more accurate signaling of congestion. ’ To be used effectively ...prompted the need for more effective congestion control policies. Currently No Gateway Policy is used to relieve and signal congestion, which leads to

Formal Semantics and Implementation of BPMN 2.0 Inclusive Gateways

NASA Astrophysics Data System (ADS)

Christiansen, David Raymond; Carbone, Marco; Hildebrandt, Thomas

We present the first direct formalization of the semantics of inclusive gateways as described in the Business Process Modeling Notation (BPMN) 2.0 Beta 1 specification. The formal semantics is given for a minimal subset of BPMN 2.0 containing just the inclusive and exclusive gateways and the start and stop events. By focusing on this subset we achieve a simple graph model that highlights the particular non-local features of the inclusive gateway semantics. We sketch two ways of implementing the semantics using algorithms based on incrementally updated data structures and also discuss distributed communication-based implementations of the two algorithms.

Deep Space Gateway Science Opportunities

NASA Technical Reports Server (NTRS)

Quincy, C. D.; Charles, J. B.; Hamill, Doris; Sidney, S. C.

2018-01-01

The NASA Life Sciences Research Capabilities Team (LSRCT) has been discussing deep space research needs for the last two years. NASA's programs conducting life sciences studies - the Human Research Program, Space Biology, Astrobiology, and Planetary Protection - see the Deep Space Gateway (DSG) as affording enormous opportunities to investigate biological organisms in a unique environment that cannot be replicated in Earth-based laboratories or on Low Earth Orbit science platforms. These investigations may provide in many cases the definitive answers to risks associated with exploration and living outside Earth's protective magnetic field. Unlike Low Earth Orbit or terrestrial locations, the Gateway location will be subjected to the true deep space spectrum and influence of both galactic cosmic and solar particle radiation and thus presents an opportunity to investigate their long-term exposure effects. The question of how a community of biological organisms change over time within the harsh environment of space flight outside of the magnetic field protection can be investigated. The biological response to the absence of Earth's geomagnetic field can be studied for the first time. Will organisms change in new and unique ways under these new conditions? This may be specifically true on investigations of microbial communities. The Gateway provides a platform for microbiology experiments both inside, to improve understanding of interactions between microbes and human habitats, and outside, to improve understanding of microbe-hardware interactions exposed to the space environment.

SCORPION persistent surveillance system with universal gateway

NASA Astrophysics Data System (ADS)

Coster, Michael; Chambers, Jon; Winters, Michael; Belesi, Joe

2008-04-01

This paper addresses benefits derived from the universal gateway utilized in Northrop Grumman Systems Corporation's (NGSC) SCORPION, a persistent surveillance and target recognition system produced by the Xetron campus in Cincinnati, Ohio. SCORPION is currently deployed in Operations Iraqi Freedom (OIF) and Enduring Freedom (OEF). The SCORPION universal gateway is a flexible, field programmable system that provides integration of over forty Unattended Ground Sensor (UGS) types from a variety of manufacturers, multiple visible and thermal electro-optical (EO) imagers, and numerous long haul satellite and terrestrial communications links, including the Army Research Lab (ARL) Blue Radio. Xetron has been integrating best in class sensors with this universal gateway to provide encrypted data exfiltration and remote sensor command and control since 1998. SCORPION data can be distributed point to point, or to multiple Common Operational Picture (COP) systems, including Command and Control Personal Computer (C2PC), Common Data Interchange Format for the Situational Awareness Display (CDIF/SAD), Force XXI Battle Command Brigade and Below (FBCB2), Defense Common Ground Systems (DCGS), and Remote Automated Position Identification System (RAPIDS).

Building a gateway with open source software for secure-DICOM communication over insecure networks

NASA Astrophysics Data System (ADS)

Emmel, Dirk; Ricke, Jens; Stohlmann, Lutz; Haderer, Alexander; Felix, Roland

2002-05-01

For Teleradiology the exchange of DICOM-images is needed for several purposes. Existing solutions often don't consider about the needs for data security and data privacy. Communication is done without any encryption over insecure networks or with encryption using proprietary solutions, which reduces the data communication possibilities to partners with the same equipment. Our goal was to build a gateway, which offers a transparent solution for secure DICOM-communication in a heterogeneous environment We developed a PC-based gateway system with DICOM-communication to the in-house network and secure DICOM communication for the communication over the insecure network. One gateway installed at each location is responsible for encryption/decryption. The sender just transfers the image data over the DICOM protocol to the local gateway. The gateway forwards the data to the gateway on the destination site using the secure DICOM protocol, which is part of the DICOM standard. The receiving gateway forwards the image data to the final destination again using the DICOM-Protocol. The gateway is based on Open Source software and runs under several operating systems. Our experience shows a reliable solution, which solves security issues for DICOM communication of image data and integrates seamless into a heterogeneous DICOM environment.

Shield Optimization in Simple Geometry for the Gateway Concept

NASA Technical Reports Server (NTRS)

Tripathi, R. K.; Simonsen, L. C.; Nealy, J. E.; Troutman, P. A.; Wilson, J. W.

2002-01-01

The great cost of added radiation shielding is a potential limiting factor in many deep space missions. For this enabling technology, we are developing tools for optimized shield design over multi-segmented missions involving multiple work and living areas in the transport and duty phase of various space missions. The total shield mass over all pieces of equipment and habitats is optimized subject to career dose and dose rate constraints. Preliminary studies of deep space missions indicate that for long duration space missions, improved shield materials will be required. The details of this new method and its impact on space missions and other technologies will be discussed. This study will provide a vital tool for evaluating Gateway designs in their usage context. Providing protection against the hazards of space radiation is one of the challenges to the Gateway infrastructure designs. We will use the mission optimization software to scope the impact of Gateway operations on human exposures and the effectiveness of alternate shielding materials on Gateway infrastructure designs. This study will provide a guide to the effectiveness of multifunctional materials in preparation to more detailed geometry studies in progress.

Updates to SCORPION persistent surveillance system with universal gateway

NASA Astrophysics Data System (ADS)

Coster, Michael; Chambers, Jon; Winters, Michael; Brunck, Al

2008-10-01

This paper addresses benefits derived from the universal gateway utilized in Northrop Grumman Systems Corporation's (NGSC) SCORPION, a persistent surveillance and target recognition system produced by the Xetron campus in Cincinnati, Ohio. SCORPION is currently deployed in Operations Iraqi Freedom (OIF) and Enduring Freedom (OEF). The SCORPION universal gateway is a flexible, field programmable system that provides integration of over forty Unattended Ground Sensor (UGS) types from a variety of manufacturers, multiple visible and thermal electro-optical (EO) imagers, and numerous long haul satellite and terrestrial communications links, including the Army Research Lab (ARL) Blue Radio. Xetron has been integrating best in class sensors with this universal gateway to provide encrypted data exfiltration to Common Operational Picture (COP) systems and remote sensor command and control since 1998. In addition to being fed to COP systems, SCORPION data can be visualized in the Common sensor Status (CStat) graphical user interface that allows for viewing and analysis of images and sensor data from up to seven hundred SCORPION system gateways on single or multiple displays. This user friendly visualization enables a large amount of sensor data and imagery to be used as actionable intelligence by a minimum number of analysts.

Development of the gateway recycling cloning system for multiple linking of expression cassettes in a defined order, and direction on gateway compatible binary vectors.

PubMed

Kimura, Tetsuya; Nakao, Akihide; Murata, Sachiko; Kobayashi, Yasuyuki; Tanaka, Yuji; Shibahara, Kenta; Kawazu, Tetsu; Nakagawa, Tsuyoshi

2013-01-01

We developed the Gateway recycling cloning system, which allows multiple linking of expression cassettes by multiple rounds of the Gateway LR reaction. Employing this system, the recycling donor vector pRED419 was subjected to the first LR reaction with an attR1-attR2 type destination vector. Then conversion vector pCON was subjected to an LR reaction to restore the attR1-attR2 site on the destination vector for the next cloning cycle. By repetition of these two simple steps, we linked four expression cassettes of a reporter gene in Gateway binary vector pGWB1, introduced the constructs into tobacco BY-2 cells, and observed the expression of transgenes.

78 FR 57371 - Agency Information Collection Activities; Comment Request; Student Aid Internet Gateway (SAIG...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-18

...; Comment Request; Student Aid Internet Gateway (SAIG) Enrollment Document AGENCY: Federal Student Aid (FSA... Internet Gateway (SAIG) Enrollment Document. OMB Control Number: 1845-0002. Type of Review: A revision of... Internet Gateway (SAIG) allows eligible entities to securely exchange Title IV, Higher Education Act (HEA...

Deep Space Gateway "Recycler" Mission

NASA Astrophysics Data System (ADS)

Graham, L.; Fries, M.; Hamilton, J.; Landis, R.; John, K.; O'Hara, W.

2018-02-01

Use of the Deep Space Gateway provides a hub for a reusable planetary sample return vehicle for missions to gather star dust as well as samples from various parts of the solar system including main belt asteroids, near-Earth asteroids, and Mars moon.

THE REMOTE SENSING DATA GATEWAY

EPA Science Inventory

The EPA Remote Sensing Data Gateway (RSDG) is a pilot project in the National Exposure Research Laboratory (NERL) to develop a comprehensive data search, acquisition, delivery and archive mechanism for internal, national and international sources of remote sensing data for the co...

Expansion of the gateway multisite recombination cloning toolkit.

PubMed

Shearin, Harold K; Dvarishkis, Alisa R; Kozeluh, Craig D; Stowers, R Steven

2013-01-01

Precise manipulation of transgene expression in genetic model organisms has led to advances in understanding fundamental mechanisms of development, physiology, and genetic disease. Transgene construction is, however, a precondition of transgene expression, and often limits the rate of experimental progress. Here we report an expansion of the modular Gateway MultiSite recombination-cloning platform for high efficiency transgene assembly. The expansion includes two additional destination vectors and entry clones for the LexA binary transcription system, among others. These new tools enhance the expression levels possible with Gateway MultiSite generated transgenes and make possible the generation of LexA drivers and reporters with Gateway MultiSite cloning. In vivo data from transgenic Drosophila functionally validating each novel component are presented and include neuronal LexA drivers, LexAop2 red and green fluorescent synaptic vesicle reporters, TDC2 and TRH LexA, GAL4, and QF drivers, and LexAop2, UAS, and QUAS channelrhodopsin2 T159C reporters.

Communication-Gateway Software For NETEX, DECnet, And TCP/IP

NASA Technical Reports Server (NTRS)

Keith, B.; Ferry, D.; Fendler, E.

1990-01-01

Communications gateway software, GATEWAY, provides process-to-process communication between remote applications programs in different protocol domains. Communicating peer processes may be resident on any paired combination of NETEX, DECnet, or TCP/IP hosts. Provides necessary mapping from one protocol to another and facilitates practical intermachine communications in cost-effective manner by eliminating need to standardize on single protocol or to implement multiple protocols in host computers. Written in Ada.

Matroshka AstroRad Radiation Experiment (MARE) on the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Gaza, R.; Hussein, H.; Murrow, D.; Hopkins, J.; Waterman, G.; Milstein, O.; Berger, T.; Przybyla, B.; Aeckerlein, J.; Marsalek, K.; Matthiae, D.; Rutczynska, A.

2018-02-01

The Matroshka AstroRad Radiation Experiment is a science payload on Orion EM-1 flight. A research platform derived from MARE is proposed for the Deep Space Gateway. Feedback is invited on desired Deep Space Gateway design features to maximize its science potential.

Research Possibilities Beyond Deep Space Gateway

NASA Astrophysics Data System (ADS)

Smitherman, D. V.; Needham, D. H.; Lewis, R.

2018-02-01

This abstract explores the possibilities for a large research facilities module attached to the Deep Space Gateway, using the same large module design and basic layout planned for the Deep Space Transport.

A Dual-Process Discrete-Time Survival Analysis Model: Application to the Gateway Drug Hypothesis

ERIC Educational Resources Information Center

Malone, Patrick S.; Lamis, Dorian A.; Masyn, Katherine E.; Northrup, Thomas F.

2010-01-01

The gateway drug model is a popular conceptualization of a progression most substance users are hypothesized to follow as they try different legal and illegal drugs. Most forms of the gateway hypothesis are that "softer" drugs lead to "harder," illicit drugs. However, the gateway hypothesis has been notably difficult to…

Optimization Shield Materials Trade Study for Lunar/Gateway Mission

NASA Technical Reports Server (NTRS)

Tripathi, R. K.; Wilson, J. W.; Cucinotta, F. A.; Anderson, B. M.; Simonsen, L. C.

2002-01-01

The great cost of added radiation shielding is a potential limiting factor in many deep space missions. For this enabling technology, we are developing tools for optimized shield design over multi-segmented missions involving multiple work and living areas in the transport and duty phase of various space missions. The total shield mass over all pieces of equipment and habitats is optimized subject to career dose and dose rate constraints. Preliminary studies of deep space missions indicate that for long duration space missions, improved shield materials will be required. The details of this new method and its impact on space missions and other technologies will be discussed. This study will provide a vital tool for evaluating Gateway designs in their usage context. Providing protection against the hazards of space radiation is one of the challenges to the Gateway infrastructure designs. We will use the mission optimization software to scope the impact of Gateway operations on human exposures and the effectiveness of alternate shielding materials on Gateway infrastructure designs. It is being proposed to use Moon and the Lagrange points as the hub for deep space missions. This study will provide a guide to the effectiveness of multifunctional materials in preparation to more detailed geometry studies in progress.

Wireless Internet Gateways (WINGS)

DTIC Science & Technology

1997-01-01

WIRELESS INTERNET GATEWAYS (WINGS) J.J. Garcia-Luna-Aceves, Chane L. Fullmer, Ewerton Madruga Computer Engineering Department University of...rooftop.com Abstract— Today’s internetwork technology has been extremely success- ful in linking huge numbers of computers and users. However, to date...this technology has been oriented to computer interconnection in relatively stable operational environments, and thus cannot adequately support many of

Copyright, Licensing Agreements and Gateways.

ERIC Educational Resources Information Center

Elias, Arthur W.

1990-01-01

Discusses technological developments in information distribution and management in relation to concepts of ownership. A historical overview of the concept of copyright is presented; licensing elements for databases are examined; and implications for gateway systems are explored, including ownership, identification of users, and allowable uses of…

Expanding the chemical information science gateway.

PubMed

Bajorath, Jürgen

2017-01-01

Broadly defined, chemical information science (CIS) covers chemical structure and data analysis including biological activity data as well as processing, organization, and retrieval of any form of chemical information. The CIS Gateway (CISG) of F1000Research was created to communicate research involving the entire spectrum of chemical information, including chem(o)informatics. CISG provides a forum for high-quality publications and a meaningful alternative to conventional journals. This gateway is supported by leading experts in the field recognizing the need for open science and a flexible publication platform enabling off-the-beaten path contributions. This editorial aims to further rationalize the scope of CISG, position it within its scientific environment, and open it up to a wider audience. Chemical information science is an interdisciplinary field with high potential to interface with experimental work.

GATEWAY Report Brief: SSL Demonstration: Long-Term Evaluation of Indoor Field Performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

Report brief summarizing a GATEWAY program evaluation of the long-term performance characteristics (chromaticity change, maintained illuminance, and operations and maintenance) of LED lighting systems in four field installations previously documented in separate DOE GATEWAY reports.

A plasmid toolkit for cloning chimeric cDNAs encoding customized fusion proteins into any Gateway destination expression vector

PubMed Central

2013-01-01

Background Valuable clone collections encoding the complete ORFeomes for some model organisms have been constructed following the completion of their genome sequencing projects. These libraries are based on Gateway cloning technology, which facilitates the study of protein function by simplifying the subcloning of open reading frames (ORF) into any suitable destination vector. The expression of proteins of interest as fusions with functional modules is a frequent approach in their initial functional characterization. A limited number of Gateway destination expression vectors allow the construction of fusion proteins from ORFeome-derived sequences, but they are restricted to the possibilities offered by their inbuilt functional modules and their pre-defined model organism-specificity. Thus, the availability of cloning systems that overcome these limitations would be highly advantageous. Results We present a versatile cloning toolkit for constructing fully-customizable three-part fusion proteins based on the MultiSite Gateway cloning system. The fusion protein components are encoded in the three plasmids integral to the kit. These can recombine with any purposely-engineered destination vector that uses a heterologous promoter external to the Gateway cassette, leading to the in-frame cloning of an ORF of interest flanked by two functional modules. In contrast to previous systems, a third part becomes available for peptide-encoding as it no longer needs to contain a promoter, resulting in an increased number of possible fusion combinations. We have constructed the kit’s component plasmids and demonstrate its functionality by providing proof-of-principle data on the expression of prototype fluorescent fusions in transiently-transfected cells. Conclusions We have developed a toolkit for creating fusion proteins with customized N- and C-term modules from Gateway entry clones encoding ORFs of interest. Importantly, our method allows entry clones obtained from ORFeome

A plasmid toolkit for cloning chimeric cDNAs encoding customized fusion proteins into any Gateway destination expression vector.

PubMed

Buj, Raquel; Iglesias, Noa; Planas, Anna M; Santalucía, Tomàs

2013-08-20

Valuable clone collections encoding the complete ORFeomes for some model organisms have been constructed following the completion of their genome sequencing projects. These libraries are based on Gateway cloning technology, which facilitates the study of protein function by simplifying the subcloning of open reading frames (ORF) into any suitable destination vector. The expression of proteins of interest as fusions with functional modules is a frequent approach in their initial functional characterization. A limited number of Gateway destination expression vectors allow the construction of fusion proteins from ORFeome-derived sequences, but they are restricted to the possibilities offered by their inbuilt functional modules and their pre-defined model organism-specificity. Thus, the availability of cloning systems that overcome these limitations would be highly advantageous. We present a versatile cloning toolkit for constructing fully-customizable three-part fusion proteins based on the MultiSite Gateway cloning system. The fusion protein components are encoded in the three plasmids integral to the kit. These can recombine with any purposely-engineered destination vector that uses a heterologous promoter external to the Gateway cassette, leading to the in-frame cloning of an ORF of interest flanked by two functional modules. In contrast to previous systems, a third part becomes available for peptide-encoding as it no longer needs to contain a promoter, resulting in an increased number of possible fusion combinations. We have constructed the kit's component plasmids and demonstrate its functionality by providing proof-of-principle data on the expression of prototype fluorescent fusions in transiently-transfected cells. We have developed a toolkit for creating fusion proteins with customized N- and C-term modules from Gateway entry clones encoding ORFs of interest. Importantly, our method allows entry clones obtained from ORFeome collections to be used without prior

XDS-I Gateway Development for HIE Connectivity with Legacy PACS at Gil Hospital.

PubMed

Simalango, Mikael Fernandus; Kim, Youngchul; Seo, Young Tae; Choi, Young Hwan; Cho, Yong Kyun

2013-12-01

The ability to support healthcare document sharing is imperative in a health information exchange (HIE). Sharing imaging documents or images, however, can be challenging, especially when they are stored in a picture archiving and communication system (PACS) archive that does not support document sharing via standard HIE protocols. This research proposes a standard-compliant imaging gateway that enables connectivity between a legacy PACS and the entire HIE. Investigation of the PACS solutions used at Gil Hospital was conducted. An imaging gateway application was then developed using a Java technology stack. Imaging document sharing capability enabled by the gateway was tested by integrating it into Gil Hospital's order communication system and its HIE infrastructure. The gateway can acquire radiology images from a PACS storage system, provide and register the images to Gil Hospital's HIE for document sharing purposes, and make the images retrievable by a cross-enterprise document sharing document viewer. Development of an imaging gateway that mediates communication between a PACS and an HIE can be considered a viable option when the PACS does not support the standard protocol for cross-enterprise document sharing for imaging. Furthermore, the availability of common HIE standards expedites the development and integration of the imaging gateway with an HIE.

XDS-I Gateway Development for HIE Connectivity with Legacy PACS at Gil Hospital

PubMed Central

Simalango, Mikael Fernandus; Kim, Youngchul; Seo, Young Tae; Cho, Yong Kyun

2013-01-01

Objectives The ability to support healthcare document sharing is imperative in a health information exchange (HIE). Sharing imaging documents or images, however, can be challenging, especially when they are stored in a picture archiving and communication system (PACS) archive that does not support document sharing via standard HIE protocols. This research proposes a standard-compliant imaging gateway that enables connectivity between a legacy PACS and the entire HIE. Methods Investigation of the PACS solutions used at Gil Hospital was conducted. An imaging gateway application was then developed using a Java technology stack. Imaging document sharing capability enabled by the gateway was tested by integrating it into Gil Hospital's order communication system and its HIE infrastructure. Results The gateway can acquire radiology images from a PACS storage system, provide and register the images to Gil Hospital's HIE for document sharing purposes, and make the images retrievable by a cross-enterprise document sharing document viewer. Conclusions Development of an imaging gateway that mediates communication between a PACS and an HIE can be considered a viable option when the PACS does not support the standard protocol for cross-enterprise document sharing for imaging. Furthermore, the availability of common HIE standards expedites the development and integration of the imaging gateway with an HIE. PMID:24523994

The DoD Gateway Information System (DGIS): The DoD Microcomputer User's Gateway to the World.

ERIC Educational Resources Information Center

Kuhn, Allan D.; Cotter, Gladys A.

1988-01-01

Describes the U.S. Department of Defense (DoD) Gateway Information System, which provides communications capabilities and access to online databases for DoD microcomputer end-users. Functions, structure, development, and artificial intelligence applications of the system are discussed. (11 references) (MES)

Evaluation of R1-6 gateway treatment alternatives for pedestrian crossings.

DOT National Transportation Integrated Search

2016-02-01

A series of studies evaluated the Gateway configuration of R1-6 in-street signs. A : Gateway configuration consists of an R1-6 sign on the centerline, an R1-6 signs on both edges of : the roadway, and R1-6 signs on the lane lines if it is a multilane...

Expanding the chemical information science gateway

PubMed Central

Bajorath, Jürgen

2017-01-01

Broadly defined, chemical information science (CIS) covers chemical structure and data analysis including biological activity data as well as processing, organization, and retrieval of any form of chemical information. The CIS Gateway (CISG) of F1000Research was created to communicate research involving the entire spectrum of chemical information, including chem(o)informatics. CISG provides a forum for high-quality publications and a meaningful alternative to conventional journals. This gateway is supported by leading experts in the field recognizing the need for open science and a flexible publication platform enabling off-the-beaten path contributions. This editorial aims to further rationalize the scope of CISG, position it within its scientific environment, and open it up to a wider audience. Chemical information science is an interdisciplinary field with high potential to interface with experimental work. PMID:29043072

High-performance parallel interface to synchronous optical network gateway

DOEpatents

St. John, Wallace B.; DuBois, David H.

1998-08-11

A digital system provides sending and receiving gateways for HIPPI interfaces. Electronic logic circuitry formats data signals and overhead signals in a data frame that is suitable for transmission over a connecting fiber optic link. Multiplexers route the data and overhead signals to a framer module. The framer module allocates the data and overhead signals to a plurality of 9-byte words that are arranged in a selected protocol. The formatted words are stored in a storage register for output through the gateway.

A Remote Health Monitoring System for the Elderly Based on Smart Home Gateway

PubMed Central

Shao, Minggang

2017-01-01

This paper proposed a remote health monitoring system for the elderly based on smart home gateway. The proposed system consists of three parts: the smart clothing, the smart home gateway, and the health care server. The smart clothing collects the elderly's electrocardiogram (ECG) and motion signals. The home gateway is used for data transmission. The health care server provides services of data storage and user information management; it is constructed on the Windows-Apache-MySQL-PHP (WAMP) platform and is tested on the Ali Cloud platform. To resolve the issues of data overload and network congestion of the home gateway, an ECG compression algorithm is applied. System demonstration shows that the ECG signals and motion signals of the elderly can be monitored. Evaluation of the compression algorithm shows that it has a high compression ratio and low distortion and consumes little time, which is suitable for home gateways. The proposed system has good scalability, and it is simple to operate. It has the potential to provide long-term and continuous home health monitoring services for the elderly. PMID:29204258

A Remote Health Monitoring System for the Elderly Based on Smart Home Gateway.

PubMed

Guan, Kai; Shao, Minggang; Wu, Shuicai

2017-01-01

This paper proposed a remote health monitoring system for the elderly based on smart home gateway. The proposed system consists of three parts: the smart clothing, the smart home gateway, and the health care server. The smart clothing collects the elderly's electrocardiogram (ECG) and motion signals. The home gateway is used for data transmission. The health care server provides services of data storage and user information management; it is constructed on the Windows-Apache-MySQL-PHP (WAMP) platform and is tested on the Ali Cloud platform. To resolve the issues of data overload and network congestion of the home gateway, an ECG compression algorithm is applied. System demonstration shows that the ECG signals and motion signals of the elderly can be monitored. Evaluation of the compression algorithm shows that it has a high compression ratio and low distortion and consumes little time, which is suitable for home gateways. The proposed system has good scalability, and it is simple to operate. It has the potential to provide long-term and continuous home health monitoring services for the elderly.

GATEWAY Demonstrations: Long-Term Evaluation of SSL Field Performance in Select Interior Projects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, Tess E.; Davis, Robert G.; Wilkerson, Andrea M.

The GATEWAY program evaluated the long-term performance characteristics (chromaticity change, maintained illuminance, and operations and maintenance) of LED lighting systems in four field installations previously documented in separate DOE GATEWAY reports.

Exploiting Multisite Gateway and pENFRUIT plasmid collection for fruit genetic engineering.

PubMed

Estornell, Leandro H; Granell, Antonio; Orzaez, Diego

2012-01-01

MultiSite Gateway cloning techniques based on homologous recombination facilitate the combinatorial assembly of basic genetic pieces (i.e., promoters, CDS, and terminators) into gene expression or gene silencing cassettes. pENFRUIT is a collection of MultiSite Triple Gateway Entry vectors dedicated to genetic engineering in fruits. It comprises a number of fruit-operating promoters as well as C-terminal tags adapted to the Gateway standard. In this way, flanking regulatory/labeling sequences can be easily Gateway-assembled with a given gene of interest for its ectopic expression or silencing in fruits. The resulting gene constructs can be analyzed in stable transgenic plants or in transient expression assays, the latter allowing fast testing of the increasing number of combinations arising from MultiSite methodology. A detailed description of the use of MultiSite cloning methodology for the assembly of pENFRUIT elements is presented.

Expansion of the Gateway MultiSite Recombination Cloning Toolkit

PubMed Central

Shearin, Harold K.; Dvarishkis, Alisa R.; Kozeluh, Craig D.; Stowers, R. Steven

2013-01-01

Precise manipulation of transgene expression in genetic model organisms has led to advances in understanding fundamental mechanisms of development, physiology, and genetic disease. Transgene construction is, however, a precondition of transgene expression, and often limits the rate of experimental progress. Here we report an expansion of the modular Gateway MultiSite recombination-cloning platform for high efficiency transgene assembly. The expansion includes two additional destination vectors and entry clones for the LexA binary transcription system, among others. These new tools enhance the expression levels possible with Gateway MultiSite generated transgenes and make possible the generation of LexA drivers and reporters with Gateway MultiSite cloning. In vivo data from transgenic Drosophila functionally validating each novel component are presented and include neuronal LexA drivers, LexAop2 red and green fluorescent synaptic vesicle reporters, TDC2 and TRH LexA, GAL4, and QF drivers, and LexAop2, UAS, and QUAS channelrhodopsin2 T159C reporters. PMID:24204935

Design of an MSAT-X mobile transceiver and related base and gateway stations

NASA Technical Reports Server (NTRS)

Fang, Russell J. F.; Bhaskar, Udaya; Hemmati, Farhad; Mackenthun, Kenneth M.; Shenoy, Ajit

1987-01-01

This paper summarizes the results of a design study of the mobile transceiver, base station, and gateway station for NASA's proposed Mobile Satellite Experiment (MSAT-X). Major ground segment system design issues such as frequency stability control, modulation method, linear predictive coding vocoder algorithm, and error control technique are addressed. The modular and flexible transceiver design is described in detail, including the core, RF/IF, modem, vocoder, forward error correction codec, amplitude-companded single sideband, and input/output modules, as well as the flexible interface. Designs for a three-carrier base station and a 10-carrier gateway station are also discussed, including the interface with the controllers and with the public-switched telephone networks at the gateway station. Functional specifications are given for the transceiver, the base station, and the gateway station.

Design of an MSAT-X mobile transceiver and related base and gateway stations

NASA Astrophysics Data System (ADS)

Fang, Russell J. F.; Bhaskar, Udaya; Hemmati, Farhad; Mackenthun, Kenneth M.; Shenoy, Ajit

This paper summarizes the results of a design study of the mobile transceiver, base station, and gateway station for NASA's proposed Mobile Satellite Experiment (MSAT-X). Major ground segment system design issues such as frequency stability control, modulation method, linear predictive coding vocoder algorithm, and error control technique are addressed. The modular and flexible transceiver design is described in detail, including the core, RF/IF, modem, vocoder, forward error correction codec, amplitude-companded single sideband, and input/output modules, as well as the flexible interface. Designs for a three-carrier base station and a 10-carrier gateway station are also discussed, including the interface with the controllers and with the public-switched telephone networks at the gateway station. Functional specifications are given for the transceiver, the base station, and the gateway station.

Access control mechanism of wireless gateway based on open flow

NASA Astrophysics Data System (ADS)

Peng, Rong; Ding, Lei

2017-08-01

In order to realize the access control of wireless gateway and improve the access control of wireless gateway devices, an access control mechanism of SDN architecture which is based on Open vSwitch is proposed. The mechanism utilizes the features of the controller--centralized control and programmable. Controller send access control flow table based on the business logic. Open vSwitch helps achieve a specific access control strategy based on the flow table.

America's freight transportation gateways : connecting our nation to places and markets abroad : [2004

DOT National Transportation Integrated Search

2004-01-01

Transportation gateways - seaports, airports, and land border crossings - are the entry and exit points for international merchandise trade between the United States and countries around the world. During the past decade, the leading U.S. gateways ha...

77 FR 21996 - Certain Equipment for Communications Networks, Including Switches, Routers, Gateways, Bridges...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-12

... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-778] Certain Equipment for Communications Networks, Including Switches, Routers, Gateways, Bridges, Wireless Access Points, Cable Modems, IP Phones... networks, including switches, routers, gateways, bridges, wireless access points, cable modems, IP phones...

Gateway integrated transportation in strategy and implementation

DOT National Transportation Integrated Search

2004-03-01

Building on the 2001 Waterborne Transportation Study, which summarized the results of Gateways Phase I ferry-expansion effort, this report analyses several ferry landing sights in terms of their potential for expansion. The report looks at watersi...

Design and implementation of Skype USB user gateway software

NASA Astrophysics Data System (ADS)

Qi, Yang

2017-08-01

With the widespread application of VoIP, the client with private protocol becomes more and more popular. Skype is one of the representatives. How to connect Skype with PSTN just by Skype client has gradually become hot. This paper design and implement the software based on a kind of USB User Gateway. With the software Skype user can freely communicate with PSTN phone. FSM is designed as the core of the software, and Skype control is separated by the USB Gateway control. In this way, the communication becomes more flexible and efficient. In the actual user testing, the software obtains good results.

Gateway's Horizon: A Center of Excellence

ERIC Educational Resources Information Center

Herring, Jayne; Colony, Lee

2007-01-01

This article describes Gateway Technical College's Horizon Center for Transportation Technology, located in Kenosha, Wisconsin, which was the product of collaboration with business and industry, community support and a U.S. Department of Labor (DOL) grant. The center, which opened this fall, is a prime example of a sustainable community…

Middle Miocene paleoenvironmental crises in Central Eurasia caused by changes in marine gateway configuration

NASA Astrophysics Data System (ADS)

Palcu, D. V.; Golovina, L. A.; Vernyhorova, Y. V.; Popov, S. V.; Krijgsman, W.

2017-11-01

Marine gateways prove to be important factors for changes in the ecology and biochemistry of marginal seas. Changes in gateway configuration played a dominant role in the Middle Miocene paleogeographic evolution of the Paratethys Sea that covered Central Eurasia. Here, we focus on the connection between the Central (CP) and Eastern Paratethys (EP) to understand the paleoenvironmental changes caused by the evolution of this marine gateway. We first construct an integrated magneto-biostratigraphic framework for the late Langhian-Serravallian (Chokrakian-Karaganian-Konkian-Volhynian) sedimentary record of the eastern domain, which allows a correlation to the well-dated successions west of the gateway. The magneto-biostratigraphic results from the Zelensky-Panagia section on the Black Sea coast of Russia show that the Chokrakian/Karaganian boundary has an age of 13.8 Ma, the Karaganian/Konkian boundary is dated at 13.4 Ma, and the Konkian/Volhynian boundary at 12.65 Ma. We identify three major phases on gateway functioning that are reflected in specific environmental changes. During the Karaganian, the EP turned into a lake-sea that supplied a unidirectional flow of low-salinity waters to the west, where the CP sea experienced its Badenian Salinity Crisis. This configuration is remarkably similar to the Mediterranean during its Messinian Salinity Crisis. The second phase is marked by a marine transgression from the west, reinstalling open-marine conditions in the CP and causing marine incursions in the EP during the Konkian. The Volhynian is characterized by a new gateway configuration that allows exchange between CP and EP, creating unified conditions all over the Paratethys. We hypothesize that a density driven pumping mechanism is triggered by the increase in connectivity at the Konkian/Volhynian boundary, which simultaneously caused major paleoenvironmental changes at both sides of the gateway and led to the Badenian-Sarmatian extinction event in the CP.

Science and Exploration Deep Space Gateway Workshop

NASA Technical Reports Server (NTRS)

Spann, James F.

2017-01-01

We propose a workshop whose outcome is a publically disseminated product that articulates SMD investigations and HEOMD Life Science research, including international collaborations, that are made possible by the new opportunities in space that result from the Deep Space Gateway.

Autonomous Science Operations Technologies for Deep Space Gateway

NASA Astrophysics Data System (ADS)

Barnes, P. K.; Haddock, A. T.; Cruzen, C. A.

2018-02-01

Autonomous Science Operations Technologies for Deep Space Gateway (DSG) is an overview of how the DSG would benefit from autonomous systems utilizing proven technologies performing telemetry monitoring and science operations.

Advanced distributed simulation technology: Digital Voice Gateway Reference Guide

NASA Astrophysics Data System (ADS)

Vanhook, Dan; Stadler, Ed

1994-01-01

The Digital Voice Gateway (referred to as the 'DVG' in this document) transmits and receives four full duplex encoded speech channels over the Ethernet. The information in this document applies only to DVG's running firmware of the version listed on the title page. This document, previously named Digital Voice Gateway Reference Guide, BBN Systems and Technologies Corporation, Cambridge, MA 02138, was revised for revision 2.00. This new revision changes the network protocol used by the DVG, to comply with the SINCGARS radio simulation (For SIMNET 6.6.1). Because of the extensive changes to revision 2.00 a separate document was created rather than supplying change pages.

A Smart Kitchen for Ambient Assisted Living

PubMed Central

Blasco, Rubén; Marco, Álvaro; Casas, Roberto; Cirujano, Diego; Picking, Richard

2014-01-01

The kitchen environment is one of the scenarios in the home where users can benefit from Ambient Assisted Living (AAL) applications. Moreover, it is the place where old people suffer from most domestic injuries. This paper presents a novel design, implementation and assessment of a Smart Kitchen which provides Ambient Assisted Living services; a smart environment that increases elderly and disabled people's autonomy in their kitchen-related activities through context and user awareness, appropriate user interaction and artificial intelligence. It is based on a modular architecture which integrates a wide variety of home technology (household appliances, sensors, user interfaces, etc.) and associated communication standards and media (power line, radio frequency, infrared and cabled). Its software architecture is based on the Open Services Gateway initiative (OSGi), which allows building a complex system composed of small modules, each one providing the specific functionalities required, and can be easily scaled to meet our needs. The system has been evaluated by a large number of real users (63) and carers (31) in two living labs in Spain and UK. Results show a large potential of system functionalities combined with good usability and physical, sensory and cognitive accessibility. PMID:24445412

A smart kitchen for ambient assisted living.

PubMed

Blasco, Rubén; Marco, Álvaro; Casas, Roberto; Cirujano, Diego; Picking, Richard

2014-01-17

The kitchen environment is one of the scenarios in the home where users can benefit from Ambient Assisted Living (AAL) applications. Moreover, it is the place where old people suffer from most domestic injuries. This paper presents a novel design, implementation and assessment of a Smart Kitchen which provides Ambient Assisted Living services; a smart environment that increases elderly and disabled people's autonomy in their kitchen-related activities through context and user awareness, appropriate user interaction and artificial intelligence. It is based on a modular architecture which integrates a wide variety of home technology (household appliances, sensors, user interfaces, etc.) and associated communication standards and media (power line, radio frequency, infrared and cabled). Its software architecture is based on the Open Services Gateway initiative (OSGi), which allows building a complex system composed of small modules, each one providing the specific functionalities required, and can be easily scaled to meet our needs. The system has been evaluated by a large number of real users (63) and carers (31) in two living labs in Spain and UK. Results show a large potential of system functionalities combined with good usability and physical, sensory and cognitive accessibility.

Front-End/Gateway Software: Availability and Usefulness.

ERIC Educational Resources Information Center

Kesselman, Martin

1985-01-01

Reviews features of front-end software packages (interface between user and online system)--database selection, search strategy development, saving and downloading, hardware and software requirements, training and documentation, online systems and database accession, and costs--and discusses gateway services (user searches through intermediary…

Dust Measurements Onboard the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Horanyi, M.; Kempf, S.; Malaspina, D.; Poppe, A.; Srama, R.; Sternovsky, Z.; Szalay, J.

2018-02-01

A dust instrument onboard the Deep Space Gateway will revolutionize our understanding of the dust environment at 1 AU, help our understanding of the evolution of the solar system, and improve dust hazard models for the safety of crewed and robotic missions.

An Integrated Science Glovebox for the Gateway Habitat

NASA Astrophysics Data System (ADS)

Calaway, M. J.; Evans, C. A.; Garrison, D. H.; Bell, M. S.

2018-02-01

A Deep Space Gateway astromaterials glovebox facility would enable science to return to Earth collected astromaterials from the Moon and ultimately Mars. Next generation habitats will benefit from on-board glovebox capability.

Questioning the Pace and Pathway of E-Government Development in Africa: A Case Study of South Africa's Cape Gateway Project

ERIC Educational Resources Information Center

Maumbe, Blessing Mukabeta; Owei, Vesper; Alexander, Helen

2008-01-01

The paper examines e-government development in Africa. This study is based on the Cape Gateway project in South Africa, a leading e-government initiative on the continent. We observe that African countries have jumped on the e-government band wagon by looking mostly at the benefits without a clear risk assessment. We argue that African countries…

Evaluation of R1-6 gateway treatment alternatives for pedestrian crossings : final report.

DOT National Transportation Integrated Search

2016-02-01

A series of studies evaluated the Gateway configuration of R1-6 in-street signs. A Gateway configuration consists of an R1-6 sign on the centerline, an R1-6 signs on both edges of the roadway, and R1-6 signs on the lane lines if it is a multilane roa...

76 FR 48834 - Michigan Consolidated Gas Company and Dawn Gateway Pipeline, LLC; Notice of Application

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-09

...'s Belle River-St. Clair Pipeline into the new 21-mile long Dawn Gateway Pipeline system, which... & Optimization, DTE Pipeline/Dawn Gateway LLC, One Energy Plaza, Detroit, MI 48226, phone (313) 235-6531 or e...

Eocene cooling linked to early flow across the Tasmanian Gateway.

PubMed

Bijl, Peter K; Bendle, James A P; Bohaty, Steven M; Pross, Jörg; Schouten, Stefan; Tauxe, Lisa; Stickley, Catherine E; McKay, Robert M; Röhl, Ursula; Olney, Matthew; Sluijs, Appy; Escutia, Carlota; Brinkhuis, Henk

2013-06-11

The warmest global temperatures of the past 85 million years occurred during a prolonged greenhouse episode known as the Early Eocene Climatic Optimum (52-50 Ma). The Early Eocene Climatic Optimum terminated with a long-term cooling trend that culminated in continental-scale glaciation of Antarctica from 34 Ma onward. Whereas early studies attributed the Eocene transition from greenhouse to icehouse climates to the tectonic opening of Southern Ocean gateways, more recent investigations invoked a dominant role of declining atmospheric greenhouse gas concentrations (e.g., CO2). However, the scarcity of field data has prevented empirical evaluation of these hypotheses. We present marine microfossil and organic geochemical records spanning the early-to-middle Eocene transition from the Wilkes Land Margin, East Antarctica. Dinoflagellate biogeography and sea surface temperature paleothermometry reveal that the earliest throughflow of a westbound Antarctic Counter Current began ~49-50 Ma through a southern opening of the Tasmanian Gateway. This early opening occurs in conjunction with the simultaneous onset of regional surface water and continental cooling (2-4 °C), evidenced by biomarker- and pollen-based paleothermometry. We interpret that the westbound flowing current flow across the Tasmanian Gateway resulted in cooling of Antarctic surface waters and coasts, which was conveyed to global intermediate waters through invigorated deep convection in southern high latitudes. Although atmospheric CO2 forcing alone would provide a more uniform middle Eocene cooling, the opening of the Tasmanian Gateway better explains Southern Ocean surface water and global deep ocean cooling in the apparent absence of (sub-) equatorial cooling.

Eocene cooling linked to early flow across the Tasmanian Gateway

PubMed Central

Bijl, Peter K.; Bendle, James A. P.; Bohaty, Steven M.; Pross, Jörg; Schouten, Stefan; Tauxe, Lisa; Stickley, Catherine E.; McKay, Robert M.; Röhl, Ursula; Olney, Matthew; Sluijs, Appy; Escutia, Carlota; Brinkhuis, Henk; Klaus, Adam; Fehr, Annick; Williams, Trevor; Carr, Stephanie A.; Dunbar, Robert B.; Gonzàlez, Jhon J.; Hayden, Travis G.; Iwai, Masao; Jimenez-Espejo, Francisco J.; Katsuki, Kota; Kong, Gee Soo; Nakai, Mutsumi; Passchier, Sandra; Pekar, Stephen F.; Riesselman, Christina; Sakai, Toyosaburo; Shrivastava, Prakash K.; Sugisaki, Saiko; Tuo, Shouting; van de Flierdt, Tina; Welsh, Kevin; Yamane, Masako

2013-01-01

The warmest global temperatures of the past 85 million years occurred during a prolonged greenhouse episode known as the Early Eocene Climatic Optimum (52–50 Ma). The Early Eocene Climatic Optimum terminated with a long-term cooling trend that culminated in continental-scale glaciation of Antarctica from 34 Ma onward. Whereas early studies attributed the Eocene transition from greenhouse to icehouse climates to the tectonic opening of Southern Ocean gateways, more recent investigations invoked a dominant role of declining atmospheric greenhouse gas concentrations (e.g., CO2). However, the scarcity of field data has prevented empirical evaluation of these hypotheses. We present marine microfossil and organic geochemical records spanning the early-to-middle Eocene transition from the Wilkes Land Margin, East Antarctica. Dinoflagellate biogeography and sea surface temperature paleothermometry reveal that the earliest throughflow of a westbound Antarctic Counter Current began ∼49–50 Ma through a southern opening of the Tasmanian Gateway. This early opening occurs in conjunction with the simultaneous onset of regional surface water and continental cooling (2–4 °C), evidenced by biomarker- and pollen-based paleothermometry. We interpret that the westbound flowing current flow across the Tasmanian Gateway resulted in cooling of Antarctic surface waters and coasts, which was conveyed to global intermediate waters through invigorated deep convection in southern high latitudes. Although atmospheric CO2 forcing alone would provide a more uniform middle Eocene cooling, the opening of the Tasmanian Gateway better explains Southern Ocean surface water and global deep ocean cooling in the apparent absence of (sub-) equatorial cooling. PMID:23720311

An Analysis of Gateway Technical College Instructors' Opinions on Secondary and Postsecondary Program Alignment

ERIC Educational Resources Information Center

Albrecht, Bryan D.

2011-01-01

The purpose of this study was to determine what opinions Gateway Technical College instructors had toward secondary and postsecondary program alignment. Student transition is critical to supporting the mission and vision of Gateway Technical College. The impetus for this study was twofold. First, the quality improvement process established at…

A Standard-Based and Context-Aware Architecture for Personal Healthcare Smart Gateways.

PubMed

Santos, Danilo F S; Gorgônio, Kyller C; Perkusich, Angelo; Almeida, Hyggo O

2016-10-01

The rising availability of Personal Health Devices (PHDs) capable of Personal Network Area (PAN) communication and the desire of keeping a high quality of life are the ingredients of the Connected Health vision. In parallel, a growing number of personal and portable devices, like smartphones and tablet computers, are becoming capable of taking the role of health gateway, that is, a data collector for the sensor PHDs. However, as the number of PHDs increase, the number of other peripherals connected in PAN also increases. Therefore, PHDs are now competing for medium access with other devices, decreasing the Quality of Service (QoS) of health applications in the PAN. In this article we present a reference architecture to prioritize PHD connections based on their state and requirements, creating a healthcare Smart Gateway. Healthcare context information is extracted by observing the traffic through the gateway. A standard-based approach was used to identify health traffic based on ISO/IEEE 11073 family of standards. A reference implementation was developed showing the relevance of the problem and how the proposed architecture can assist in the prioritization. The reference Smart Gateway solution was integrated with a Connected Health System for the Internet of Things, validating its use in a real case scenario.

The Gateway Paper--proposed health reforms in Pakistan--interface considerations.

PubMed

Nishtar, Sania

2006-12-01

The Gateway Paper recognizes three system interfaces as being critical to the delivery of healthcare within Pakistan. These include the federal/provincial interface, the provincial-district interface and the public-private interface. A number of gaps in each area have been highlighted. At the federal-provincial interface lack of provincial ownership of federal initiatives, gaps in provincial counterpart arrangements, ambiguities about federal and provincial roles and responsibilities, conflicts over sharing of resources and gaps in understanding provincial requirements and poor coordination have been articulated as core issues. It is envisaged that the development of a broad based mechanism to develop a consensus on national policy positions, incorporation of appropriate guidance from the provinces, giving provinces an active participatory role in decision-making, garnering their support and clearly demarcating roles and responsibilities will obviate some of these issues as would the institutionalization of a federal-provincial coordinating mechanism to review actions at both levels with regards to progress on meeting stipulating goals. At a district level poor governance, limited capacity within the system, lag in granting full district level financial and administrative autonomy, and lack of operational clarity in the rules of business have contributed to the challenge. This is compounded by inadvertent centralization of some functions within the district, which political and administrative decentralization has paradoxically created and impediments to harnessing the role of communities. The clear delineation of these issues provides a substrate, which need to be at the heart of strategic reform within the context of the recent devolution initiative. At the public-private interface the absence of locally established principles, legislative frameworks, policies and operational strategies have been contributing to the adhoc nature of public-private engagement within

Gateway: An earth orbiting transportation node

NASA Technical Reports Server (NTRS)

1988-01-01

University of Texas Mission Design (UTMD) has outlined the components that a space based transportation facility must include in order to support the first decade of Lunar base buildup. After studying anticipated traffic flow to and from the hub, and taking into account crew manhour considerations, propellant storage, orbital transfer vehicle maintenance requirements, and orbital mechanics, UTMD arrived at a design for the facility. The amount of activity directly related to supporting Lunar base traffic is too high to allow the transportation hub to be part of the NASA Space Station. Instead, a separate structure should be constructed and dedicated to handling all transportation-related duties. UTMD found that the structure (named Gateway) would need a permanent crew of four to perform maintenance tasks on the orbital transfer and orbital maneuvering vehicles and to transfer payload from launch vehicles to the orbital transfer vehicles. In addition, quarters for 4 more persons should be allocated for temporary accommodation of Lunar base crew passing through Gateway. UTMD was careful to recommend an expendable structure that can adapt to meet the growing needs of the American space program.

WorldWideScience.org: the global science gateway.

PubMed

Fitzpatrick, Roberta Bronson

2009-10-01

WorldWideScience.org is a Web-based global gateway connecting users to both national and international scientific databases and portals. This column will provide background information on the resource as well as introduce basic searching practices for users.

Van Allen Probes Science Gateway and Space Weather Data Processing

NASA Astrophysics Data System (ADS)

Romeo, G.; Barnes, R. J.; Weiss, M.; Fox, N. J.; Mauk, B.; Potter, M.; Kessel, R.

2014-12-01

The Van Allen Probes Science Gateway acts as a centralized interface to the instrument Science Operation Centers (SOCs), provides mission planning tools, and hosts a number of science related activities such as the mission bibliography. Most importantly, the Gateway acts as the primary site for processing and delivering the VAP Space Weather data to users. Over the past year, the web-site has been completely redesigned with the focus on easier navigation and improvements of the existing tools such as the orbit plotter, position calculator and magnetic footprint tool. In addition, a new data plotting facility has been added. Based on HTML5, which allows users to interactively plot Van Allen Probes summary and space weather data. The user can tailor the tool to display exactly the plot they wish to see and then share this with other users via either a URL or by QR code. Various types of plots can be created, including simple time series, data plotted as a function of orbital location, and time versus L-Shell. We discuss the new Van Allen Probes Science Gateway and the Space Weather Data Pipeline.

Multi-Modal Traveler Information System - Gateway Design Options

DOT National Transportation Integrated Search

1997-05-19

The purpose of this working paper is to provide insight into the options that are available from which to design the Gateway Traveler Information System (TIS). This working paper will discuss each option in a general manner without becoming overly te...

GATEWAY Report Brief: OLED Lighting in the Offices of Aurora Lighting Design, Inc.

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

Summary of a GATEWAY report evaluation at the offices of Aurora Lighting Design, Inc., in Grayslake, IL, where the GATEWAY program conducted its first investigation involving OLED lighting. The project experienced several challenges, but also highlighted a number of promising attributes – which indicate that with continued improvements in efficacy, longevity, size, and flexibility, OLEDs could provide a new tool for creative and effective lighting.

"Gateway" Districts Struggle to Serve Immigrant Parents

ERIC Educational Resources Information Center

Maxwell, Lesli A.

2012-01-01

As thousands of communities--especially in the South--became booming gateways for immigrant families during the 1990s and the early years of the new century, public schools struggled with the unfamiliar task of serving the large numbers of English-learners arriving in their classrooms. Instructional programs were built from scratch. Districts had…

77 FR 46435 - Notice To All Interested Parties of the Termination of the Receivership of 10146, Gateway Bank of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-03

... Receivership of 10146, Gateway Bank of St. Louis, St. Louis, MO Notice is hereby given that the Federal Deposit Insurance Corporation (``FDIC'') as Receiver for Gateway Bank of St. Louis, (``the Receiver'') intends to terminate its receivership for said institution. The FDIC was appointed receiver of Gateway Bank of St...

47 CFR 10.320 - Provider alert gateway requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Provider alert gateway requirements. 10.320 Section 10.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM... that each Participating Commercial Mobile Service provider is required to support and perform at its...

Calculus ABCs: A Gateway for Freshman Calculus

ERIC Educational Resources Information Center

Fulton, Scott R.

2003-01-01

This paper describes a gateway testing program designed to ensure that students acquire basic skills in freshman calculus. Students must demonstrate they have mastered standards for "Absolutely Basic Competency"--the Calculus ABCs--in order to pass the course with a grade of C or better. We describe the background, standards, and testing program.…

Role of Marine Gateways in the Paleoceanography of the Miocene Mediterranean Sea; A Model Study

NASA Astrophysics Data System (ADS)

de la Vara, A.; Meijer, P. T.

2015-12-01

During the Miocene, due to the convergence of the African plate and the Eurasian plate, the Mediterranean region was subject to profound paleogeographic changes. The evolving coastline and bathymetry of the Mediterranean Sea and, in particular, the opening and closure of the marine connections between the Mediterranean and the outside oceans, triggered important changes in Mediterranean circulation and, indirectly, also affected the global-scale ocean circulation. Until about the Middle Miocene the proto-Mediterranean Sea was open to the Indo-Pacific Ocean through the so-called Indian Gateway. Although the exact age of closure of this gateway is still debated, it is accepted that it substantially affected the paleoceanography of the Mediterranean Sea. Later in time, during the Late Miocene, the Mediterranean was only connected to the Atlantic Ocean but by two marine corridors: the Betic and Rifian corridors. Closure of these narrow passages resulted in the Messinian Salinity Crisis, during which a sequence of evaporites was deposited throughout the Mediterranean basin. In this work we use a regional-scale ocean general circulation model (the Princeton Ocean Model) to gain insight into the role of the evolving gateways. The analysis focuses on large-scale (overturning) circulation, patterns of exchange in the gateways and properties of the Mediterranean water. By comparing our model results to geological data we are able to propose new scenarios or rule out previously proposed ones, and determine the conditions evidenced by the geological observations. More specifically we investigate two different topics: (i) the effects of shoaling and closure of the Indian Gateway and (ii) the functioning of the Late Miocene double gateway to the Atlantic.

Gateway to Careers. Postsecondary VSO Hones Workplace Skills.

ERIC Educational Resources Information Center

Vernezze, Michael; Henkel, Marjorie

1993-01-01

The Gateway Marketing and Management Association is a local chapter of Delta Epsilon Chi, the postsecondary affiliate of Distributive Education Clubs of America. This vocational student organization provides leadership training and marketing skill development to prepare students for competition at state and national levels. (JOW)

A Gateway for Phylogenetic Analysis Powered by Grid Computing Featuring GARLI 2.0

PubMed Central

Bazinet, Adam L.; Zwickl, Derrick J.; Cummings, Michael P.

2014-01-01

We introduce molecularevolution.org, a publicly available gateway for high-throughput, maximum-likelihood phylogenetic analysis powered by grid computing. The gateway features a garli 2.0 web service that enables a user to quickly and easily submit thousands of maximum likelihood tree searches or bootstrap searches that are executed in parallel on distributed computing resources. The garli web service allows one to easily specify partitioned substitution models using a graphical interface, and it performs sophisticated post-processing of phylogenetic results. Although the garli web service has been used by the research community for over three years, here we formally announce the availability of the service, describe its capabilities, highlight new features and recent improvements, and provide details about how the grid system efficiently delivers high-quality phylogenetic results. [garli, gateway, grid computing, maximum likelihood, molecular evolution portal, phylogenetics, web service.] PMID:24789072

Starshade Assembly Enabled by the Deep Space Gateway Architecture

NASA Astrophysics Data System (ADS)

Grunsfeld, J. M.; Siegler, N.; Mukherjee, R.

2018-02-01

A starshade is a large external coronagraph which will allow the direct imaging and analysis of planets around nearby stars. We present how the Deep Space Gateway would enable the robotic/astronaut construction of a starshade.

GATEWAY Demonstrations: Exploring SSL Product Performance in the Real World

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Fact sheet that outlines DOE's GATEWAY technology demonstration program, which evaluates high-performance SSL products for general illumination in a variety of real-world exterior and interior applications.

All gates lead to smoking: the 'gateway theory', e-cigarettes and the remaking of nicotine.

PubMed

Bell, Kirsten; Keane, Helen

2014-10-01

The idea that drug use in 'softer' forms leads to 'harder' drug use lies at the heart of the gateway theory, one of the most influential models of drug use of the twentieth century. Although hotly contested, the notion of the 'gateway drug' continues to rear its head in discussions of drug use--most recently in the context of electronic cigarettes. Based on a critical reading of a range of texts, including scholarly literature and media reports, we explore the history and gestation of the gateway theory, highlighting the ways in which intersections between academic, media and popular accounts actively produced the concept. Arguing that the theory has been critical in maintaining the distinction between 'soft' and 'hard' drugs, we turn to its distinctive iteration in the context of debates about e-cigarettes. We show that the notion of the 'gateway' has been transformed from a descriptive to a predictive model, one in which nicotine is constituted as simultaneously 'soft' and 'hard'--as both relatively innocuous and incontrovertibly harmful. Copyright © 2014 Elsevier Ltd. All rights reserved.

Early experiences in developing and managing the neuroscience gateway.

PubMed

Sivagnanam, Subhashini; Majumdar, Amit; Yoshimoto, Kenneth; Astakhov, Vadim; Bandrowski, Anita; Martone, MaryAnn; Carnevale, Nicholas T

2015-02-01

The last few decades have seen the emergence of computational neuroscience as a mature field where researchers are interested in modeling complex and large neuronal systems and require access to high performance computing machines and associated cyber infrastructure to manage computational workflow and data. The neuronal simulation tools, used in this research field, are also implemented for parallel computers and suitable for high performance computing machines. But using these tools on complex high performance computing machines remains a challenge because of issues with acquiring computer time on these machines located at national supercomputer centers, dealing with complex user interface of these machines, dealing with data management and retrieval. The Neuroscience Gateway is being developed to alleviate and/or hide these barriers to entry for computational neuroscientists. It hides or eliminates, from the point of view of the users, all the administrative and technical barriers and makes parallel neuronal simulation tools easily available and accessible on complex high performance computing machines. It handles the running of jobs and data management and retrieval. This paper shares the early experiences in bringing up this gateway and describes the software architecture it is based on, how it is implemented, and how users can use this for computational neuroscience research using high performance computing at the back end. We also look at parallel scaling of some publicly available neuronal models and analyze the recent usage data of the neuroscience gateway.

Early experiences in developing and managing the neuroscience gateway

PubMed Central

Sivagnanam, Subhashini; Majumdar, Amit; Yoshimoto, Kenneth; Astakhov, Vadim; Bandrowski, Anita; Martone, MaryAnn; Carnevale, Nicholas. T.

2015-01-01

SUMMARY The last few decades have seen the emergence of computational neuroscience as a mature field where researchers are interested in modeling complex and large neuronal systems and require access to high performance computing machines and associated cyber infrastructure to manage computational workflow and data. The neuronal simulation tools, used in this research field, are also implemented for parallel computers and suitable for high performance computing machines. But using these tools on complex high performance computing machines remains a challenge because of issues with acquiring computer time on these machines located at national supercomputer centers, dealing with complex user interface of these machines, dealing with data management and retrieval. The Neuroscience Gateway is being developed to alleviate and/or hide these barriers to entry for computational neuroscientists. It hides or eliminates, from the point of view of the users, all the administrative and technical barriers and makes parallel neuronal simulation tools easily available and accessible on complex high performance computing machines. It handles the running of jobs and data management and retrieval. This paper shares the early experiences in bringing up this gateway and describes the software architecture it is based on, how it is implemented, and how users can use this for computational neuroscience research using high performance computing at the back end. We also look at parallel scaling of some publicly available neuronal models and analyze the recent usage data of the neuroscience gateway. PMID:26523124

Competitive Swarm Optimizer Based Gateway Deployment Algorithm in Cyber-Physical Systems

PubMed Central

Huang, Shuqiang; Tao, Ming

2017-01-01

Wireless sensor network topology optimization is a highly important issue, and topology control through node selection can improve the efficiency of data forwarding, while saving energy and prolonging lifetime of the network. To address the problem of connecting a wireless sensor network to the Internet in cyber-physical systems, here we propose a geometric gateway deployment based on a competitive swarm optimizer algorithm. The particle swarm optimization (PSO) algorithm has a continuous search feature in the solution space, which makes it suitable for finding the geometric center of gateway deployment; however, its search mechanism is limited to the individual optimum (pbest) and the population optimum (gbest); thus, it easily falls into local optima. In order to improve the particle search mechanism and enhance the search efficiency of the algorithm, we introduce a new competitive swarm optimizer (CSO) algorithm. The CSO search algorithm is based on an inter-particle competition mechanism and can effectively avoid trapping of the population falling into a local optimum. With the improvement of an adaptive opposition-based search and its ability to dynamically parameter adjustments, this algorithm can maintain the diversity of the entire swarm to solve geometric K-center gateway deployment problems. The simulation results show that this CSO algorithm has a good global explorative ability as well as convergence speed and can improve the network quality of service (QoS) level of cyber-physical systems by obtaining a minimum network coverage radius. We also find that the CSO algorithm is more stable, robust and effective in solving the problem of geometric gateway deployment as compared to the PSO or Kmedoids algorithms. PMID:28117735

Competitive Swarm Optimizer Based Gateway Deployment Algorithm in Cyber-Physical Systems.

PubMed

Huang, Shuqiang; Tao, Ming

2017-01-22

Wireless sensor network topology optimization is a highly important issue, and topology control through node selection can improve the efficiency of data forwarding, while saving energy and prolonging lifetime of the network. To address the problem of connecting a wireless sensor network to the Internet in cyber-physical systems, here we propose a geometric gateway deployment based on a competitive swarm optimizer algorithm. The particle swarm optimization (PSO) algorithm has a continuous search feature in the solution space, which makes it suitable for finding the geometric center of gateway deployment; however, its search mechanism is limited to the individual optimum (pbest) and the population optimum (gbest); thus, it easily falls into local optima. In order to improve the particle search mechanism and enhance the search efficiency of the algorithm, we introduce a new competitive swarm optimizer (CSO) algorithm. The CSO search algorithm is based on an inter-particle competition mechanism and can effectively avoid trapping of the population falling into a local optimum. With the improvement of an adaptive opposition-based search and its ability to dynamically parameter adjustments, this algorithm can maintain the diversity of the entire swarm to solve geometric K -center gateway deployment problems. The simulation results show that this CSO algorithm has a good global explorative ability as well as convergence speed and can improve the network quality of service (QoS) level of cyber-physical systems by obtaining a minimum network coverage radius. We also find that the CSO algorithm is more stable, robust and effective in solving the problem of geometric gateway deployment as compared to the PSO or Kmedoids algorithms.

Working research codes into fluid dynamics education: a science gateway approach

NASA Astrophysics Data System (ADS)

Mason, Lachlan; Hetherington, James; O'Reilly, Martin; Yong, May; Jersakova, Radka; Grieve, Stuart; Perez-Suarez, David; Klapaukh, Roman; Craster, Richard V.; Matar, Omar K.

2017-11-01

Research codes are effective for illustrating complex concepts in educational fluid dynamics courses, compared to textbook examples, an interactive three-dimensional visualisation can bring a problem to life! Various barriers, however, prevent the adoption of research codes in teaching: codes are typically created for highly-specific `once-off' calculations and, as such, have no user interface and a steep learning curve. Moreover, a code may require access to high-performance computing resources that are not readily available in the classroom. This project allows academics to rapidly work research codes into their teaching via a minimalist `science gateway' framework. The gateway is a simple, yet flexible, web interface allowing students to construct and run simulations, as well as view and share their output. Behind the scenes, the common operations of job configuration, submission, monitoring and post-processing are customisable at the level of shell scripting. In this talk, we demonstrate the creation of an example teaching gateway connected to the Code BLUE fluid dynamics software. Student simulations can be run via a third-party cloud computing provider or a local high-performance cluster. EPSRC, UK, MEMPHIS program Grant (EP/K003976/1), RAEng Research Chair (OKM).

Gateway to College: Lessons from Implementing a Rigorous Academic Program for At-Risk Young People

ERIC Educational Resources Information Center

Willard, Jacklyn Altuna; Bayes, Brian; Martinez, John

2015-01-01

This study reports on the implementation of Gateway to College, a program whose mission is to serve students who have dropped out of high school, or who are at risk of dropping out of high school, by allowing them to earn a high school diploma and credits toward a postsecondary degree. Gateway to College is uniquely ambitious in providing…

Heliophysics Radio Observations Enabled by the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Kasper, J. C.

2018-02-01

This presentation reviews the scientific potential of low frequency radio imaging from space, the SunRISE radio interferometer, and the scientific value of larger future arrays in deep space and how they would benefit from the Deep Space Gateway.

Efficient preparation of shuffled DNA libraries through recombination (Gateway) cloning.

PubMed

Lehtonen, Soili I; Taskinen, Barbara; Ojala, Elina; Kukkurainen, Sampo; Rahikainen, Rolle; Riihimäki, Tiina A; Laitinen, Olli H; Kulomaa, Markku S; Hytönen, Vesa P

2015-01-01

Efficient and robust subcloning is essential for the construction of high-diversity DNA libraries in the field of directed evolution. We have developed a more efficient method for the subcloning of DNA-shuffled libraries by employing recombination cloning (Gateway). The Gateway cloning procedure was performed directly after the gene reassembly reaction, without additional purification and amplification steps, thus simplifying the conventional DNA shuffling protocols. Recombination-based cloning, directly from the heterologous reassembly reaction, conserved the high quality of the library and reduced the time required for the library construction. The described method is generally compatible for the construction of DNA-shuffled gene libraries. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

A Life-Course Perspective on the "Gateway Hypothesis"

ERIC Educational Resources Information Center

Van Gundy, Karen; Rebellon, Cesar J.

2010-01-01

Drawing on stress and life-course perspectives and using panel data from 1,286 south Florida young adults, we assess three critical questions regarding the role of marijuana in the "gateway hypothesis." First, does teen marijuana use independently (causally) affect subsequent use of more dangerous substances? Second, if so, does that…

2. WILLITS SIGN. GATEWAY TO THE REDWOODS. WILLITS, MENDOCINO COUNTY, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. WILLITS SIGN. GATEWAY TO THE REDWOODS. WILLITS, MENDOCINO COUNTY, CALIFORNIA. LOOKING NW. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

67. WILLITS SIGN. GATEWAY TO THE REDWOODS. WILLITS, MENDOCINO COUNTY, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

67. WILLITS SIGN. GATEWAY TO THE REDWOODS. WILLITS, MENDOCINO COUNTY, CALIFORNIA. LOOKING NW. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

Remote Sensing Information Gateway (RSIG3D) Fact Sheet

EPA Pesticide Factsheets

The Remote Sensing Information Gateway-3D (RSIG3D) is a free and downloadable application that provides easy and secure access to petabytes (millions of gigabytes) of atmospheric data that can be used to study complex air quality issues.

Advances in Planetary Protection at the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Spry, J. A.; Siegel, B.; Race, M.; Rummel, J. D.; Pugel, D. E.; Groen, F. J.; Kminek, G.; Conley, C. A.; Carosso, N. J.

2018-02-01

Planetary protection knowledge gaps that can be addressed by science performed at the Deep Space Gateway in the areas of human health and performance, space biology, and planetary sciences that enable future exploration in deep space, at Mars, and other targets.

Impact Flash Monitoring Facility on the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Needham, D. H.; Moser, D. E.; Suggs, R. M.; Cooke, W. J.; Kring, D. A.; Neal, C. R.; Fassett, C. I.

2018-02-01

Cameras mounted to the Deep Space Gateway exterior will detect flashes caused by impacts on the lunar surface. Observed flashes will help constrain the current lunar impact flux and assess hazards faced by crews living and working in cislunar space.

RBDMS, FracFocus, and Gateway Initiatives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yates, Dan

Award DE-FE-0000880 from the Department of Energy to the Ground Water Protection Council (GWPC) focuses on state and federal priorities in the areas of state RBDMS development, connectivity between state systems and FracFocus.org, and data sharing initiatives across agencies. The overarching goals of these projects are to: - upgrade the Risk Based Data Management System (RBDMS) to a web based application; - upgrade the RBDMS user interface to make it more intuitive and easier to use - increase connectivity between state RBDMS systems and FracFocus; - provide outreach to states and agencies through training programs, special meetings, and state bymore » state outreach on all deliverables; - provide greater functionality for non-IT users; - update and install RBDMS modules in additional state programs (IL, CA, WY, WV); and; - help make data access more transparent. The primary objective is to enhance the Risk Based Data Management System (RBDMS) by adding new components relevant to current environmental topics such as hydraulic fracturing, increasing field inspection capabilities, creating linkages between FracFocus and state programs, upgrading eForm capabilities, and analyzing potential for data sharing. The GWPC will work with state agencies to develop an RBDMS module(s) that meets these needs.« less

An Interactive, Integrated, Instructional Pathway to the LEAD Science Gateway

NASA Astrophysics Data System (ADS)

Yalda, S.; Clark, R.; Davis, L.; Wiziecki, E. N.

2008-12-01

Linked Environments for Atmospheric Discovery (LEAD) is a bold and revolutionary paradigm that through a Web-based Service Oriented Architecture (SOA) exposes the user to a rich environment of data, models, data mining and visualization and analysis tools, enabling the user to ask science questions of applications while the complexity of the software and middleware managing these applications is hidden from the user. From its inception in 2003, LEAD has championed goals that have context for the future of weather and related research and education. LEAD espouses to lowering the barrier for using complex end-to-end weather technologies by a) democratizing the availability of advanced weather technologies, b) empowering the user of these technologies to tackle a variety of problems, and c) facilitating learning and understanding. LEAD, as it exists today, is poised to enable a diverse community of scientists, educators, students, and operational practitioners. The project has been informed by atmospheric and computer scientists, educators, and educational consultants who, in search of new knowledge, understanding, ideas, and learning methodologies, seek easy access to new capabilities that allow for user-directed and interactive query and acquisition, simulation, assimilation, data mining, computational modeling, and visualization. As one component of the total LEAD effort, the LEAD education team has designed interactive, integrated, instructional pathways within a set of learning modules (LEAD-to-Learn) to facilitate, enhance, and enable the use of the LEAD gateway in the classroom. The LEAD education initiative focuses on the means to integrate data, tools, and services used by researchers into undergraduate meteorology education in order to provide an authentic and contextualized environment for teaching and learning. Educators, educational specialists, and students from meteorology and computer science backgrounds have collaborated on the design and development

Amplified North Atlantic warming in the late Pliocene by changes in Arctic gateways

DOE PAGES

Otto-Bliesner, Bette L.; Jahn, Alexandra; Feng, Ran; ...

2016-12-26

Under previous reconstructions of late Pliocene boundary conditions, climate models have failed to reproduce the warm sea surface temperatures reconstructed in the North Atlantic. Using a reconstruction of mid-Piacenzian paleogeography that has the Bering Strait and Canadian Arctic Archipelago Straits closed, however, improves the simulation of the proxy-indicated warm sea surface temperatures in the North Atlantic in the Community Climate System Model. We find that the closure of these small Arctic gateways strengthens the Atlantic Meridional Overturning Circulation, by inhibiting freshwater transport from the Pacific to the Arctic Ocean and from the Arctic Ocean to the Labrador Sea, leading tomore » warmer sea surface temperatures in the North Atlantic. In conclusion, this indicates that the state of the Arctic gateways may influence the sensitivity of the North Atlantic climate in complex ways, and better understanding of the state of these Arctic gateways for past time periods is needed.« less

Relevance of Google-customized search engine vs. CISMeF quality-controlled health gateway.

PubMed

Gehanno, Jean-François; Kerdelhue, Gaétan; Sakji, Saoussen; Massari, Philippe; Joubert, Michel; Darmoni, Stéfan J

2009-01-01

CISMeF (acronym for Catalog and Index of French Language Health Resources on the Internet) is a quality-controlled health gateway conceived to catalog and index the most important and quality-controlled sources of institutional health information in French. The goal of this study is to compare the relevance of results provided by this gateway from a small set of documents selected and described by human experts to those provided by a search engine from a large set of automatically indexed and ranked resources. The Google-Customized search engine (CSE) was used. The evaluation was made using the 10th first results of 15 queries and two blinded physician evaluators. There was no significant difference between the relevance of information retrieval in CISMeF and Google CSE. In conclusion, automatic indexing does not lead to lower relevance than a manual MeSH indexing and may help to cope with the increasing number of references to be indexed in a controlled health quality gateway.

Theater gateway closure: a strategic level barricade

DTIC Science & Technology

that at the strategic level the effects are based on the economic and diplomatic elements of the national power, affecting proportionally sustainment...Seven months of detrimental political implications, expensive effects on military operations, and strategic level barricades during 2011 and 2012 in...logistical planners at the strategic level can anticipate or mitigate the effects of a theater gateway closure on military operations. Through two

A RESTful image gateway for multiple medical image repositories.

PubMed

Valente, Frederico; Viana-Ferreira, Carlos; Costa, Carlos; Oliveira, José Luis

2012-05-01

Mobile technologies are increasingly important components in telemedicine systems and are becoming powerful decision support tools. Universal access to data may already be achieved by resorting to the latest generation of tablet devices and smartphones. However, the protocols employed for communicating with image repositories are not suited to exchange data with mobile devices. In this paper, we present an extensible approach to solving the problem of querying and delivering data in a format that is suitable for the bandwidth and graphic capacities of mobile devices. We describe a three-tiered component-based gateway that acts as an intermediary between medical applications and a number of Picture Archiving and Communication Systems (PACS). The interface with the gateway is accomplished using Hypertext Transfer Protocol (HTTP) requests following a Representational State Transfer (REST) methodology, which relieves developers from dealing with complex medical imaging protocols and allows the processing of data on the server side.

Constrained Surface-Level Gateway Placement for Underwater Acoustic Wireless Sensor Networks

NASA Astrophysics Data System (ADS)

Li, Deying; Li, Zheng; Ma, Wenkai; Chen, Hong

One approach to guarantee the performance of underwater acoustic sensor networks is to deploy multiple Surface-level Gateways (SGs) at the surface. This paper addresses the connected (or survivable) Constrained Surface-level Gateway Placement (C-SGP) problem for 3-D underwater acoustic sensor networks. Given a set of candidate locations where SGs can be placed, our objective is to place minimum number of SGs at a subset of candidate locations such that it is connected (or 2-connected) from any USN to the base station. We propose a polynomial time approximation algorithm for the connected C-SGP problem and survivable C-SGP problem, respectively. Simulations are conducted to verify our algorithms' efficiency.

The Vocational Baccalaureate: A Gateway to Higher Education?

ERIC Educational Resources Information Center

Gendron, Benedicte

2009-01-01

Access to the baccalaureate and higher education in France has become more democratic. The introduction of the vocational baccalaureate has been part of this process, but remains a modest step forward given the very low take-up of vocational baccalaureate courses. If vocational education pathways in France are to become true gateways to higher…

Signaling gateway molecule pages—a data model perspective

PubMed Central

Dinasarapu, Ashok Reddy; Saunders, Brian; Ozerlat, Iley; Azam, Kenan; Subramaniam, Shankar

2011-01-01

Summary: The Signaling Gateway Molecule Pages (SGMP) database provides highly structured data on proteins which exist in different functional states participating in signal transduction pathways. A molecule page starts with a state of a native protein, without any modification and/or interactions. New states are formed with every post-translational modification or interaction with one or more proteins, small molecules or class molecules and with each change in cellular location. State transitions are caused by a combination of one or more modifications, interactions and translocations which then might be associated with one or more biological processes. In a characterized biological state, a molecule can function as one of several entities or their combinations, including channel, receptor, enzyme, transcription factor and transporter. We have also exported SGMP data to the Biological Pathway Exchange (BioPAX) and Systems Biology Markup Language (SBML) as well as in our custom XML. Availability: SGMP is available at www.signaling-gateway.org/molecule. Contact: shankar@ucsd.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:21505029

Low-Cost Planetary Missions Enabled by the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Berinstain, A.; Richards, R. D.

2018-02-01

The authors will present options for discussion among participants of how low-cost lunar and planetary missions using the Moon Express family of spacecraft can be enabled by the presence of the Deep Space Gateway.

CD68 acts as a major gateway for malaria sporozoite liver infection

PubMed Central

Cha, Sung-Jae; Park, Kiwon; Srinivasan, Prakash; Schindler, Christian W.; van Rooijen, Nico; Stins, Monique

2015-01-01

After being delivered by the bite from an infected mosquito, Plasmodium sporozoites enter the blood circulation and infect the liver. Previous evidence suggests that Kupffer cells, a macrophage-like component of the liver blood vessel lining, are traversed by sporozoites to initiate liver invasion. However, the molecular determinants of sporozoite–Kupffer cell interactions are unknown. Understanding the molecular basis for this specific recognition may lead to novel therapeutic strategies to control malaria. Using a phage display library screen, we identified a peptide, P39, that strongly binds to the Kupffer cell surface and, importantly, inhibits sporozoite Kupffer cell entry. Furthermore, we determined that P39 binds to CD68, a putative receptor for sporozoite invasion of Kupffer cells that acts as a gateway for malaria infection of the liver. PMID:26216124

CD68 acts as a major gateway for malaria sporozoite liver infection.

PubMed

Cha, Sung-Jae; Park, Kiwon; Srinivasan, Prakash; Schindler, Christian W; van Rooijen, Nico; Stins, Monique; Jacobs-Lorena, Marcelo

2015-08-24

After being delivered by the bite from an infected mosquito, Plasmodium sporozoites enter the blood circulation and infect the liver. Previous evidence suggests that Kupffer cells, a macrophage-like component of the liver blood vessel lining, are traversed by sporozoites to initiate liver invasion. However, the molecular determinants of sporozoite-Kupffer cell interactions are unknown. Understanding the molecular basis for this specific recognition may lead to novel therapeutic strategies to control malaria. Using a phage display library screen, we identified a peptide, P39, that strongly binds to the Kupffer cell surface and, importantly, inhibits sporozoite Kupffer cell entry. Furthermore, we determined that P39 binds to CD68, a putative receptor for sporozoite invasion of Kupffer cells that acts as a gateway for malaria infection of the liver. © 2015 Cha et al.

Van Allen Probes Science Gateway: A Centralized Data Access Point

NASA Astrophysics Data System (ADS)

Romeo, G.; Barnes, R. J.; Ukhorskiy, A. Y.; Sotirelis, T.; Stephens, G. K.; Kessel, R.; Potter, M.

2015-12-01

The Van Allen Probes Science Gateway acts a centralized interface to the instrument Science Operation Centers (SOCs), provides mission planning tools, and hosts a number of science related activities such as the mission bibliography. Most importantly, the Gateway acts as the primary site for processing and delivering the Van Allen Probes Space Weather data to users. Over the past years, the web-site has been completely redesigned with the focus on easier navigation and improvements of the existing tools such as the orbit plotter, position calculator and magnetic footprint tool. In addition, a new data plotting facility has been added. Based on HTML5, which allows users to interactively plot Van Allen Probes science and space weather data. The user can tailor the tool to display exactly the plot they wish to see and then share this with other users via either a URL or by QR code. Various types of plots can be created, including, simple time series, data plotted as a function of orbital location, and time versus L-Shell, capability of visualizing data from both probes (A & B) on the same plot. In cooperation with all Van Allen Probes Instrument SOCs, the Science Gateway will soon be able to serve higher level data products (Level 3), and to visualize them via the above mentioned HTML5 interface. Users will also be able to create customized CDF files on the fly.

Functional design for U.S. Coast Guard intelligent communications gateway

DOT National Transportation Integrated Search

1995-02-27

This report documents the functional design of hardware and software components necessary to satisfy the U.S. Coast Guard (USCG) requirements identified for an Intelligent Gateway (IG). The IG will transfer messages from USCG shoreside networks to tr...

A simple Gateway-assisted construction system of TALEN genes for plant genome editing.

PubMed

Kusano, Hiroaki; Onodera, Hitomi; Kihira, Miho; Aoki, Hiromi; Matsuzaki, Hikaru; Shimada, Hiroaki

2016-07-25

TALEN is an artificial nuclease being applied for sequence-specific genome editing. For the plant genome editing, a pair of TALEN genes is expressed in the cells, and a binary plasmid for Agrobacterium-mediated transformation should be assembled. We developed a novel procedure using the Gateway-assisted plasmids, named Emerald-Gateway TALEN system. We constructed entry vectors, pPlat plasmids, for construction of a desired TALEN gene using Platinum Gate TALEN kit. We also created destination plasmid, pDual35SGw1301, which allowed two TALEN genes to both DNA strands to recruit using Gateway technology. Resultant TALEN genes were evaluated by the single-strand annealing (SSA) assay in E. coli cells. By this assay, the TALENs recognized the corresponding targets in the divided luciferase gene, and induced a specific recombination to generate an active luciferase gene. Using the TALEN genes constructed, we created a transformant potato cells in which a site-specific mutation occurred at the target site of the GBSS gene. This suggested that our system worked effectively and was applicable as a convenient tool for the plant genome editing.

The Deep Space Gateway: The Next Stepping Stone to Mars

NASA Astrophysics Data System (ADS)

Cassady, R. J.; Carberry, C.; Cichan, T.

2018-02-01

Human missions to Mars will benefit from precursor missions such as the Deep Space Gateway (DSG) that achieve important science and human health and safety milestones. The DSG can perform lunar science and prepare for future Mars mission science.

Activate/Inhibit KGCS Gateway via Master Console EIC Pad-B Display

NASA Technical Reports Server (NTRS)

Ferreira, Pedro Henrique

2014-01-01

My internship consisted of two major projects for the Launch Control System.The purpose of the first project was to implement the Application Control Language (ACL) to Activate Data Acquisition (ADA) and to Inhibit Data Acquisition (IDA) the Kennedy Ground Control Sub-Systems (KGCS) Gateway, to update existing Pad-B End Item Control (EIC) Display to program the ADA and IDA buttons with new ACL, and to test and release the ACL Display.The second project consisted of unit testing all of the Application Services Framework (ASF) by March 21st. The XmlFileReader was unit tested and reached 100 coverage. The XmlFileReader class is used to grab information from XML files and use them to initialize elements in the other framework elements by using the Xerces C++ XML Parser; which is open source commercial off the shelf software. The ScriptThread was also tested. ScriptThread manages the creation and activation of script threads. A large amount of the time was used in initializing the environment and learning how to set up unit tests and getting familiar with the specific segments of the project that were assigned to us.

The Monash Portal: More Than Just a Virtual Gateway.

ERIC Educational Resources Information Center

Kennedy, David; Webster, Len; Benson, Robyn; James, Di; Bailey, Nathan

The My Monash Portal (Portal) at Monash University (Australia) provides a virtual gateway to support student-centered flexible learning by coordinating several of the university's key resources to meet the needs of students and staff. The Portal is intended to help deliver innovative learning programs, foster opportunities to undertake research,…

Tao of Gateway: Providing Internet Access to Licensed Databases.

ERIC Educational Resources Information Center

McClellan, Gregory A.; Garrison, William V.

1997-01-01

Illustrates an approach for providing networked access to licensed databases over the Internet by positioning the library between patron and vendor. Describes how the gateway systems and database connection servers work and discusses how treatment of security has evolved with the introduction of the World Wide Web. Outlines plans to reimplement…

The Weak Stability Boundary, A Gateway for Human Exploration of Space

NASA Technical Reports Server (NTRS)

Mendell, Wendell W.

2000-01-01

NASA plans for future human exploration of the Solar System describe only missions to Mars. Before such missions can be initiated, much study remains to be done in technology development, mission operations and human performance. While, for example, technology validation and operational experience could be gained in the context of lunar exploration missions, a NASA lunar program is seen as a competitor to a Mars mission rather than a step towards it. The recently characterized Weak Stability Boundary in the Earth-Moon gravitational field may provide an operational approach to all types of planetary exploration, and infrastructure developed for a gateway to the Solar System may be a programmatic solution for exploration that avoids the fractious bickering between Mars and Moon advocates. This viewpoint proposes utilizing the concept of Greater Earth to educate policy makers, opinion makers and the public about these subtle attributes of our space neighborhood.

Sharing Human-Generated Observations by Integrating HMI and the Semantic Sensor Web

PubMed Central

Sigüenza, Álvaro; Díaz-Pardo, David; Bernat, Jesús; Vancea, Vasile; Blanco, José Luis; Conejero, David; Gómez, Luis Hernández

2012-01-01

Current “Internet of Things” concepts point to a future where connected objects gather meaningful information about their environment and share it with other objects and people. In particular, objects embedding Human Machine Interaction (HMI), such as mobile devices and, increasingly, connected vehicles, home appliances, urban interactive infrastructures, etc., may not only be conceived as sources of sensor information, but, through interaction with their users, they can also produce highly valuable context-aware human-generated observations. We believe that the great promise offered by combining and sharing all of the different sources of information available can be realized through the integration of HMI and Semantic Sensor Web technologies. This paper presents a technological framework that harmonizes two of the most influential HMI and Sensor Web initiatives: the W3C's Multimodal Architecture and Interfaces (MMI) and the Open Geospatial Consortium (OGC) Sensor Web Enablement (SWE) with its semantic extension, respectively. Although the proposed framework is general enough to be applied in a variety of connected objects integrating HMI, a particular development is presented for a connected car scenario where drivers' observations about the traffic or their environment are shared across the Semantic Sensor Web. For implementation and evaluation purposes an on-board OSGi (Open Services Gateway Initiative) architecture was built, integrating several available HMI, Sensor Web and Semantic Web technologies. A technical performance test and a conceptual validation of the scenario with potential users are reported, with results suggesting the approach is sound. PMID:22778643

Sharing human-generated observations by integrating HMI and the Semantic Sensor Web.

PubMed

Sigüenza, Alvaro; Díaz-Pardo, David; Bernat, Jesús; Vancea, Vasile; Blanco, José Luis; Conejero, David; Gómez, Luis Hernández

2012-01-01

Current "Internet of Things" concepts point to a future where connected objects gather meaningful information about their environment and share it with other objects and people. In particular, objects embedding Human Machine Interaction (HMI), such as mobile devices and, increasingly, connected vehicles, home appliances, urban interactive infrastructures, etc., may not only be conceived as sources of sensor information, but, through interaction with their users, they can also produce highly valuable context-aware human-generated observations. We believe that the great promise offered by combining and sharing all of the different sources of information available can be realized through the integration of HMI and Semantic Sensor Web technologies. This paper presents a technological framework that harmonizes two of the most influential HMI and Sensor Web initiatives: the W3C's Multimodal Architecture and Interfaces (MMI) and the Open Geospatial Consortium (OGC) Sensor Web Enablement (SWE) with its semantic extension, respectively. Although the proposed framework is general enough to be applied in a variety of connected objects integrating HMI, a particular development is presented for a connected car scenario where drivers' observations about the traffic or their environment are shared across the Semantic Sensor Web. For implementation and evaluation purposes an on-board OSGi (Open Services Gateway Initiative) architecture was built, integrating several available HMI, Sensor Web and Semantic Web technologies. A technical performance test and a conceptual validation of the scenario with potential users are reported, with results suggesting the approach is sound.

Earth-from-Luna Limb Imager (ELLI) for Deep Space Gateway

NASA Astrophysics Data System (ADS)

Gorkavyi, N.; DeLand, M.

2018-02-01

The new type of limb imager with a high-frequency imaging proposed for Deep Space Gateway. Each day this CubeSat' scale imager will generate the global 3D model of the aerosol component of the Earth's atmosphere and Polar Mesospheric Clouds.

Appropriate and inappropriate methods for investigating the "gateway" hypothesis, with a review of the evidence linking prior snus use to later cigarette smoking.

PubMed

Lee, Peter N

2015-03-20

The "gateway hypothesis" usually refers to the possibility that the taking up of habit A, which is considered harmless (or less harmful), may lead to the subsequent taking up of another habit, B, which is considered harmful (or more harmful). Possible approaches to designing and analysing studies to test the hypothesis are discussed. Evidence relating to the use of snus (A) as a gateway for smoking (B) is then evaluated in detail. The importance of having appropriate data available on the sequence of use of A and B and on other potential confounding factors that may lead to the taking up of B is emphasised. Where randomised trials are impractical, the preferred designs include the prospective cohort study in which ever use of A and of B is recorded at regular intervals, and the cross-sectional survey in which time of starting to use A and B is recorded. Both approaches allow time-stratified analytical methods to be used, in which, in each time period, risk of initiating B among never users of B at the start of the interval is compared according to prior use of A. Adjustment in analysis for the potential confounding factors is essential. Of 11 studies of possible relevance conducted in Sweden, Finland or Norway, only one seriously addresses potential confounding by those other factors involved in the initiation of smoking. Furthermore, 5 of the 11 studies are of a design that does not allow proper testing of the gateway hypothesis for various reasons, and the analysis is unsatisfactory, sometimes seriously, in all the remaining six. While better analyses could be attempted for some of the six studies identified as having appropriate design, the issues of confounding remain, and more studies are clearly needed. To obtain a rapid answer, a properly designed cross-sectional survey is recommended.

Key Challenges for Life Science Payloads on the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Anthony, J. H.; Niederwieser, T.; Zea, L.; Stodieck, L.

2018-02-01

Compared to ISS, Deep Space Gateway life science payloads will be challenged by deep space radiation and non-continuous habitation. The impacts of these two differences on payload requirements, design, and operations are discussed.

Earth Observation and Science: Monitoring Vegetation Dynamics from Deep Space Gateway

NASA Astrophysics Data System (ADS)

Knyazikhin, Y.; Park, T.; Hu, B.

2018-02-01

Retrieving diurnal courses of sunlit (SLAI) and shaded (ShLAI) leaf area indices, fraction of photosynthetically active radiation (PAR) absorbed by vegetation (FPAR), and Normalized Difference Vegetation Index (NDVI) from Deep Space Gateway data.

Lunar Volatile System Dynamics: Observations Enabled by the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Honniball, C. I.; Lucey, P. G.; Petro, N.; Hurley, D.; Farrell, W.

2018-02-01

A UV spectrometer-imager and IR spectrometer are proposed to solve questions regarding the lunar volatile system. The instrument takes advantage of highly elliptical orbits and the thermal management system of the Deep Space Gateway.

Global Magnetospheric Imaging from the Deep Space Gateway in Lunar Orbit

NASA Astrophysics Data System (ADS)

Chua, D. H.; Socker, D. G.; Englert, C. R.; Carter, M. T.; Plunkett, S. P.; Korendyke, C. M.; Meier, R. R.

2018-02-01

We propose to use the Deep Space Gateway as an observing platform for a magnetospheric imager that will capture the first direct global images of the interface between the incident solar wind and the Earth's magnetosphere.

Compliance Patterns and Utilization of e-Health for Glucose Monitoring: Standalone Internet Gateway and Tablet Device.

PubMed

Rho, Mi Jung; Kim, Hun-Sung; Yoon, Kun-Ho; Choi, In Young

2017-04-01

Knowledge regarding compliance patterns and service utilization in e-health is important for the development of effective services. To develop proper e-health, the characteristics of compliance patterns and utilization of e-health should be studied. We studied these for glucose monitoring of diabetic patients from primary clinics. Data were collected from 160 outpatients who participated in e-health for glucose monitoring funded by the Korean government. Specifically, this study focused on two device types: a standalone Internet gateway and a tablet device. The SPSS 18.0 software was used for statistical analyses of demographic characteristics, survival data, and Cox proportional hazards regression model. Standalone Internet gateway users demonstrated a more stable compliance pattern than did tablet device users. The compliance rate differed according to the device type. Typically, compliance decreases considerably around 8 months. In these results, standalone Internet gateway users utilized the service for longer periods than tablet device users. Gateway type and location also influenced utilization (p < 0.05). The service should be designed according to the device type to develop appropriate service models. Thus, service designers should understand the different characteristics of service devices. This study provides insight into compliance patterns and utilization to develop appropriate service models and service interventions depending on the device.

Exploration of Near-Earth Objects from the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Dunham, D. W.; Stakkestad, K.; Vedder, P.; McAdams, J.; Horsewood, J.; Genova, A. L.

2018-02-01

The paper will show how clever use of orbital dynamics can lower delta-V costs to enable scientifically interesting missions. The high-energy Deep Space Gateway orbits can be used to reach NEOs, a trans node for crews, or to deploy small sats. Examples are given.

NOAASIS Gateway - NOAA Satellite Information System (NOAASIS); Office of

Science.gov Websites

Satellite and Product Operations » DOC » NOAA » NESDIS » NOAASIS NOAA Satellite Information System NOAASIS Gateway The NOAA Satellite Information System provides essential information for satellite direct readout station operators and users of NOAA environmental satellite data. While the emphasis is on

A Planetary Defense Gateway for Smart Discovery of relevant Information for Decision Support

NASA Technical Reports Server (NTRS)

Bambacus, Myra; Yang, Chaowei Phil; Leung, Ronald Y.; Barbee, Brent; Nuth, Joseph A.; Seery, Bernard; Jiang, Yongyao; Qin, Han; Li, Yun; Yu, Manzhu;

Environmental Dataset Gateway (EDG) Search Widget

EPA Pesticide Factsheets

Use the Environmental Dataset Gateway (EDG) to find and access EPA's environmental resources. Many options are available for easily reusing EDG content in other other applications. This allows individuals to provide direct access to EPA's metadata outside the EDG interface. The EDG Search Widget makes it possible to search the EDG from another web page or application. The search widget can be included on your website by simply inserting one or two lines of code. Users can type a search term or lucene search query in the search field and retrieve a pop-up list of records that match that search.

Laser-Assisted Wire Additive Manufacturing System for the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Foster, B. D.; Matthews, B.

2018-02-01

Investigation on the Deep Space Gateway will involve experiments/operations inside pressurized modules. Support for those experiments may necessitate a means to fabricate and repair required articles. This capability can be provided through an additive manufacturing (AM) system.

The VERCE Science Gateway: enabling user friendly seismic waves simulations across European HPC infrastructures

NASA Astrophysics Data System (ADS)

Spinuso, Alessandro; Krause, Amy; Ramos Garcia, Clàudia; Casarotti, Emanuele; Magnoni, Federica; Klampanos, Iraklis A.; Frobert, Laurent; Krischer, Lion; Trani, Luca; David, Mario; Leong, Siew Hoon; Muraleedharan, Visakh

2014-05-01

The EU-funded project VERCE (Virtual Earthquake and seismology Research Community in Europe) aims to deploy technologies which satisfy the HPC and data-intensive requirements of modern seismology. As a result of VERCE's official collaboration with the EU project SCI-BUS, access to computational resources, like local clusters and international infrastructures (EGI and PRACE), is made homogeneous and integrated within a dedicated science gateway based on the gUSE framework. In this presentation we give a detailed overview on the progress achieved with the developments of the VERCE Science Gateway, according to a use-case driven implementation strategy. More specifically, we show how the computational technologies and data services have been integrated within a tool for Seismic Forward Modelling, whose objective is to offer the possibility to perform simulations of seismic waves as a service to the seismological community. We will introduce the interactive components of the OGC map based web interface and how it supports the user with setting up the simulation. We will go through the selection of input data, which are either fetched from federated seismological web services, adopting community standards, or provided by the users themselves by accessing their own document data store. The HPC scientific codes can be selected from a number of waveform simulators, currently available to the seismological community as batch tools or with limited configuration capabilities in their interactive online versions. The results will be staged out from the HPC via a secure GridFTP transfer to a VERCE data layer managed by iRODS. The provenance information of the simulation will be automatically cataloged by the data layer via NoSQL techonologies. We will try to demonstrate how data access, validation and visualisation can be supported by a general purpose provenance framework which, besides common provenance concepts imported from the OPM and the W3C-PROV initiatives, also offers

Enhancing Return from Lunar Surface Missions via the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Chavers, D. G.; Whitley, R. J.; Percy, T. K.; Needham, D. H.; Polsgrove, T. T.

2018-02-01

The Deep Space Gateway (DSG) will facilitate access to and communication with lunar surface assets. With a science airlock, docking port, and refueling capability in an accessible orbit, the DSG will enable high priority science across the lunar surface.

Lunar Science Enabled by the Deep Space Gateway and PHASR Rover

NASA Astrophysics Data System (ADS)

Bakambu, J. N.; Shaw, A.; Fulford, P.; Osinski, G.; Bourassa, M.; Rehmatullah, F.; Zanetti, M.; Rembala, R.

2018-02-01

The Deep Space Gateway will be a tremendous boon to lunar surface science. It will enable the PHASR Rover, a concept for a Canadian rover system, with international contributions and the goal of sample acquisition and lunar surface science.

Design on intelligent gateway technique in home network

NASA Astrophysics Data System (ADS)

Hu, Zhonggong; Feng, Xiancheng

2008-12-01

Based on digitization, multimedia, mobility, wide band, real-time interaction and so on,family networks, because can provide diverse and personalized synthesis service in information, correspondence work, entertainment, education and health care and so on, are more and more paid attention by the market. The family network product development has become the focus of the related industry. In this paper,the concept of the family network and the overall reference model of the family network are introduced firstly.Then the core techniques and the correspondence standard related with the family network are proposed.The key analysis is made for the function of family gateway, the function module of the software,the key technologies to client side software architecture and the trend of development of the family network entertainment seeing and hearing service and so on. Product present situation of the family gateway and the future trend of development, application solution of the digital family service are introduced. The development of the family network product bringing about the digital family network industry is introduced finally.It causes the development of software industries,such as communication industry,electrical appliances industry, computer and game and so on.It also causes the development of estate industry.

SCORPION II persistent surveillance system with universal gateway

NASA Astrophysics Data System (ADS)

Coster, Michael; Chambers, Jonathan; Brunck, Albert

2009-05-01

This paper addresses improvements and benefits derived from the next generation Northrop Grumman SCORPION II family of persistent surveillance and target recognition systems produced by the Xetron campus in Cincinnati, Ohio. SCORPION II reduces the size, weight, and cost of all SCORPION components in a flexible, field programmable system that is easier to conceal, backward compatible, and enables integration of over forty Unattended Ground Sensor (UGS) and camera types from a variety of manufacturers, with a modular approach to supporting multiple Line of Sight (LOS) and Beyond Line of Sight (BLOS) communications interfaces. Since 1998 Northrop Grumman has been integrating best in class sensors with its proven universal modular Gateway to provide encrypted data exfiltration to Common Operational Picture (COP) systems and remote sensor command and control. In addition to being fed to COP systems, SCORPION and SCORPION II data can be directly processed using a common sensor status graphical user interface (GUI) that allows for viewing and analysis of images and sensor data from up to seven hundred SCORPION system Gateways on single or multiple displays. This GUI enables a large amount of sensor data and imagery to be used for actionable intelligence as well as remote sensor command and control by a minimum number of analysts.

Gateway National Recreation Area, Jamaica Bay Unit alternative transportation feasibility study

DOT National Transportation Integrated Search

2013-07-31

The National Park Service Gateway National Recreation Area (GATE) was created to provide convenient access to outdoor recreation in the National Park System for residents and visitors to the New York City (NYC) area. The Volpe Center completed a numb...

Lyceum: A Multi-Protocol Digital Library Gateway

NASA Technical Reports Server (NTRS)

Maa, Ming-Hokng; Nelson, Michael L.; Esler, Sandra L.

1997-01-01

Lyceum is a prototype scalable query gateway that provides a logically central interface to multi-protocol and physically distributed, digital libraries of scientific and technical information. Lyceum processes queries to multiple syntactically distinct search engines used by various distributed information servers from a single logically central interface without modification of the remote search engines. A working prototype (http://www.larc.nasa.gov/lyceum/) demonstrates the capabilities, potentials, and advantages of this type of meta-search engine by providing access to over 50 servers covering over 20 disciplines.

The Gateway Paper--stewardship and governance in the health sector in Pakistan.

PubMed

Nishtar, Sania

2006-12-01

As an opening for a dialogue on health reforms in the country, the Gateway Paper places emphasis on strengthening the stewardship function of mandated State agencies in Pakistan with particular attention to two key areas. Firstly, greater emphasis on a stewardship role for the Ministry and departments of health in the context of inter-sectoral scope of health and secondly, a stronger role for the State agencies as regulators of healthcare within the country. The Gateway Paper envisages that the role of State agencies will become more critical as new models of financing health and delivering services are structured given that these entail regulation of private sector providers, providing oversight for ensuring a system for ongoing education and implementation of frameworks for public-private partnerships. The Gateway Paper refers to stewardship with reference to analysis and overview of health policies within the country, their relationship with evidence, their follow-up into planning and finally their implementation. The Paper also provides an insight into policies from a process-related as well as content and program related perspectives. In doing so a number of questions relating to the evidence and policy disconnect; issues at strategic and operational levels of planning, and governance-related impediments to program implementation have been discussed and a viewpoint articulated on an approach to addressing these challenges.

Gateways to State and Local Government Information on the Internet.

ERIC Educational Resources Information Center

Maxwell, Bruce

1995-01-01

Describes some of the most useful gateways that can be used to access state and local government information on the Internet, including StateSearch, Council of State Governments, U.S. House of Representatives Internet Law Library, LC MARVEL, CityNet, California Home Page, and New York State Library Gopher. (LRW)

Phloem-limited reoviruses universally induce sieve element hyperplasia and more flexible gateways, providing more channels for their movement in plants.

PubMed

Lv, Ming-Fang; Xie, Li; Song, Xi-Jiao; Hong, Jian; Mao, Qian-Zhuo; Wei, Tai-Yun; Chen, Jian-Ping; Zhang, Heng-Mu

2017-11-28

Virion distribution and ultrastructural changes induced by the infection of maize or rice with four different reoviruses were examined. Rice black streaked dwarf virus (RBSDV, genus Fijivirus), Rice ragged stunt virus (RRSV, genus Oryzavirus), and Rice gall dwarf virus (RGDV, genus Phytoreovirus) were all phloem-limited and caused cellular hyperplasia in the phloem resulting in tumors or vein swelling and modifying the cellular arrangement of sieve elements (SEs). In contrast, virions of Rice dwarf virus (RDV, genus Phytoreovirus) were observed in both phloem and mesophyll and the virus did not cause hyperplasia of SEs. The three phloem-limited reoviruses (but not RDV) all induced more flexible gateways at the SE-SE interfaces, especially the non-sieve plate interfaces. These flexible gateways were also observed for the first time at the cellular interfaces between SE and phloem parenchyma (PP). In plants infected with any of the reoviruses, virus-like particles could be seen within the flexible gateways, suggesting that these gateways may serve as channels for the movement of plant reoviruses with their large virions between SEs or between SEs and PP. SE hyperplasia and the increase in flexible gateways may be a universal strategy for the movement of phloem-limited reoviruses.

Communicating Astronomy with the Public (Youth) as the Gateway to Development

NASA Astrophysics Data System (ADS)

Crabtree, Dennis R.

2015-03-01

Astronomy has a unique ability to excite and stimulate the curiosity of children. Because of this, society can use astronomy as a gateway to lead children on a path towards future learning of science and technology, and potentially to careers in these areas.

Assessment and Placement: Supporting Student Success in College Gateway Courses

ERIC Educational Resources Information Center

Vandal, Bruce

2014-01-01

Evidence is mounting that the vast majority of students who are currently placed into prerequisite remedial education could be successful in gateway college-­level courses if they receive additional academic support as a corequisite. Recent research on college placement exams reveals that the exams are unreliable at predicting college success, and…

Adolescents and Young Adults' Perceptions of Electronic Cigarettes as a Gateway to Smoking: A Qualitative Study in Switzerland

ERIC Educational Resources Information Center

Akre, Christina; Suris, Joan-Carles

2017-01-01

Electronic cigarettes (ECs) acting as a gateway to smoking traditional cigarettes (TCs) is a growing public health concern of EC use among youths. To gather the opinions and perceptions of adolescents and young adults (AYAs) on whether and how EC can act as a gateway to smoking TC among youths. A qualitative method included 42 AYAs. Participants…

Los Angeles - Gateway Freight Advanced Traveler Information System : demonstration team final report.

DOT National Transportation Integrated Search

2015-02-01

This Demonstration Team Final Report has been prepared to provide an overview of the conduct and qualitative findings of the LA-Gateway FRATIS development and testing program. More specifically, this document provides: A description of the testin...

"TIS": An Intelligent Gateway Computer for Information and Modeling Networks. Overview.

ERIC Educational Resources Information Center

Hampel, Viktor E.; And Others

TIS (Technology Information System) is being used at the Lawrence Livermore National Laboratory (LLNL) to develop software for Intelligent Gateway Computers (IGC) suitable for the prototyping of advanced, integrated information networks. Dedicated to information management, TIS leads the user to available information resources, on TIS or…

Communications Relay and Human-Assisted Sample Return from the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Cichan, T.; Hopkins, J. B.; Bierhaus, B.; Murrow, D. W.

2018-02-01

The Deep Space Gateway can enable or enhance exploration of the lunar surface through two capabilities: 1. communications relay, opening up access to the lunar farside, and 2. sample return, enhancing the ability to return large sample masses.

A Practical Evaluation of a High-Security Energy-Efficient Gateway for IoT Fog Computing Applications

PubMed Central

Castedo, Luis

2017-01-01

Fog computing extends cloud computing to the edge of a network enabling new Internet of Things (IoT) applications and services, which may involve critical data that require privacy and security. In an IoT fog computing system, three elements can be distinguished: IoT nodes that collect data, the cloud, and interconnected IoT gateways that exchange messages with the IoT nodes and with the cloud. This article focuses on securing IoT gateways, which are assumed to be constrained in terms of computational resources, but that are able to offload some processing from the cloud and to reduce the latency in the responses to the IoT nodes. However, it is usually taken for granted that IoT gateways have direct access to the electrical grid, which is not always the case: in mission-critical applications like natural disaster relief or environmental monitoring, it is common to deploy IoT nodes and gateways in large areas where electricity comes from solar or wind energy that charge the batteries that power every device. In this article, how to secure IoT gateway communications while minimizing power consumption is analyzed. The throughput and power consumption of Rivest–Shamir–Adleman (RSA) and Elliptic Curve Cryptography (ECC) are considered, since they are really popular, but have not been thoroughly analyzed when applied to IoT scenarios. Moreover, the most widespread Transport Layer Security (TLS) cipher suites use RSA as the main public key-exchange algorithm, but the key sizes needed are not practical for most IoT devices and cannot be scaled to high security levels. In contrast, ECC represents a much lighter and scalable alternative. Thus, RSA and ECC are compared for equivalent security levels, and power consumption and data throughput are measured using a testbed of IoT gateways. The measurements obtained indicate that, in the specific fog computing scenario proposed, ECC is clearly a much better alternative than RSA, obtaining energy consumption reductions of up

A Practical Evaluation of a High-Security Energy-Efficient Gateway for IoT Fog Computing Applications.

PubMed

Suárez-Albela, Manuel; Fernández-Caramés, Tiago M; Fraga-Lamas, Paula; Castedo, Luis

2017-08-29

Fog computing extends cloud computing to the edge of a network enabling new Internet of Things (IoT) applications and services, which may involve critical data that require privacy and security. In an IoT fog computing system, three elements can be distinguished: IoT nodes that collect data, the cloud, and interconnected IoT gateways that exchange messages with the IoT nodes and with the cloud. This article focuses on securing IoT gateways, which are assumed to be constrained in terms of computational resources, but that are able to offload some processing from the cloud and to reduce the latency in the responses to the IoT nodes. However, it is usually taken for granted that IoT gateways have direct access to the electrical grid, which is not always the case: in mission-critical applications like natural disaster relief or environmental monitoring, it is common to deploy IoT nodes and gateways in large areas where electricity comes from solar or wind energy that charge the batteries that power every device. In this article, how to secure IoT gateway communications while minimizing power consumption is analyzed. The throughput and power consumption of Rivest-Shamir-Adleman (RSA) and Elliptic Curve Cryptography (ECC) are considered, since they are really popular, but have not been thoroughly analyzed when applied to IoT scenarios. Moreover, the most widespread Transport Layer Security (TLS) cipher suites use RSA as the main public key-exchange algorithm, but the key sizes needed are not practical for most IoT devices and cannot be scaled to high security levels. In contrast, ECC represents a much lighter and scalable alternative. Thus, RSA and ECC are compared for equivalent security levels, and power consumption and data throughput are measured using a testbed of IoT gateways. The measurements obtained indicate that, in the specific fog computing scenario proposed, ECC is clearly a much better alternative than RSA, obtaining energy consumption reductions of up to

The impact of Southern Ocean gateways on the Cenozoic climate evolution

NASA Astrophysics Data System (ADS)

von der Heydt, Anna; Viebahn, Jan; Dijkstra, Henk

2016-04-01

During the Cenozoic period, which covers the last 65 Million (Ma) years, Earth's climate has undergone a major long-term transition from warm "greenhouse" to colder "icehouse" conditions with extensive ice sheets in the polar regions of both hemispheres. On the very long term the gradual cooling may be seen as response to the overall slowly decreasing atmospheric CO2-concentration due to weathering processes in the Earth System, however, continental geometry has changed considerably over this period and the long-term gradual trend was interrupted, by several rapid transitions as well as periods where temperature and greenhouse gas concentrations seem to be decoupled. The Eocene-Oligocene boundary (˜34 Ma, E/O) and mid-Miocene climatic transition (˜13 Ma, MCT) reflect major phases of Antarctic ice sheet build-up and global climate cooling, while Northern Hemisphere ice sheets developed much later, most likely at the Pliocene-Pleistocene transition (˜2.7Ma). Thresholds in atmospheric CO2-concentration together with feedback mechanisms related to land ice formation are now among the favoured mechanisms of these climatic transitions, while the long-proposed ocean circulation changes caused by opening of tectonic gateways seem to play a less direct role. The opening of the Southern Ocean gateways, notably the Drake Passage and the Tasman Gateway as well as the northward movement of Australia over this long time period, however, has eventually led to the development of today's strongest ocean current, the Antarctic Circumpolar Current (ACC), playing a major role in the transport properties of the global ocean circulation. The overall state of the global ocean circulation, therefore, preconditions the climate system to dramatic events such as major ice sheet formation. Here, we present results of a state-of-the art global climate model (CESM) under various continental configurations: (i) present day geometry, (ii) present day geometry with a closed Drake Passage and

Prioritizing Active Learning: An Exploration of Gateway Courses in Political Science

ERIC Educational Resources Information Center

Archer, Candace C.; Miller, Melissa K.

2011-01-01

Prior research in political science and other disciplines demonstrates the pedagogical and practical benefits of active learning. Less is known, however, about the extent to which active learning is used in political science classrooms. This study assesses the prioritization of active learning in "gateway" political science courses, paying…

Global Lunar Topography from the Deep Space Gateway for Science and Exploration

NASA Astrophysics Data System (ADS)

Archinal, B.; Gaddis, L.; Kirk, R.; Edmundson, K.; Stone, T.; Portree, D.; Keszthelyi, L.

2018-02-01

The Deep Space Gateway, in low lunar orbit, could be used to achieve a long standing goal of lunar science, collecting stereo images in two months to make a complete, uniform, high resolution, known accuracy, global topographic model of the Moon.

Retinal Evaluation Using Optical Coherence Tomography (OCT) During Deep Space Gateway Missions

NASA Astrophysics Data System (ADS)

Stenger, M. B.; Laurie, S. S.; Macias, B. R.; Barr, Y. R.

2018-02-01

Optical Coherence Tomography (OCT) imaging will be conducted before, during, and after Deep Space Gateway missions to evaluate changes in the retina and, in particular, the optic nerve head and surrounding structures. Additional parameters will be collected before and after flight.

Low-Latency Telerobotic Sample Return and Biomolecular Sequencing for Deep Space Gateway

NASA Astrophysics Data System (ADS)

Lupisella, M.; Bleacher, J.; Lewis, R.; Dworkin, J.; Wright, M.; Burton, A.; Rubins, K.; Wallace, S.; Stahl, S.; John, K.; Archer, D.; Niles, P.; Regberg, A.; Smith, D.; Race, M.; Chiu, C.; Russell, J.; Rampe, E.; Bywaters, K.

2018-02-01

Low-latency telerobotics, crew-assisted sample return, and biomolecular sequencing can be used to acquire and analyze lunar farside and/or Apollo landing site samples. Sequencing can also be used to monitor and study Deep Space Gateway environment and crew health.

It's about the Gateway Courses: Defining and Contextualizing the Issue

ERIC Educational Resources Information Center

Koch, Andrew K.

2017-01-01

This introductory chapter defines the phrase gateway courses, describes why these courses are one of the most compelling issues in the contemporary student success movement, and details what is at stake if the issues associated with these courses are left unaddressed.

GATEWAY Demonstrations: LED System Performance in a Trial Installation--Two Years Later, Yuma Border Patrol, Yuma, Arizona

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilkerson, Andrea M.; Sullivan, Gregory P.; Davis, Robert G.

Along the Yuma Sector Border Patrol Area in Yuma, Arizona, the GATEWAY program conducted a trial demonstration in which the incumbent quartz metal halide area lighting was replaced with LED at three pole locations at the Yuma Sector Border Patrol Area in Yuma, Arizona. The retrofit was documented to better understand LED technology performance in high-temperature environments. This report follows the GATEWAY Yuma Phase 1.1 Report and reflects LED system results documented two years after the demonstration began.

GATEWAY Demonstrations: LED System Performance in a Trial Installation--One Year Later, Yuma Border Patrol, Yuma, Arizona

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilkerson, A. M.; Davis, R. G.

Along the Yuma Sector Border Patrol Area in Yuma, Arizona, the GATEWAY program conducted a trial demonstration in which the incumbent quartz metal halide area lighting was replaced with LED at three pole locations at the Yuma Sector Border Patrol Area in Yuma, Arizona. The retrofit was documented to better understand LED technology performance in high-temperature environments. This report follows the GATEWAY Yuma Phase 1.0 Report and reflects LED system results documented one year after the demonstration began.

Gateways and Water Mass Mixing in the Late Cretaceous North Atlantic

NASA Astrophysics Data System (ADS)

Asgharian Rostami, M.; Martin, E. E.; MacLeod, K. G.; Poulsen, C. J.; Vande Guchte, A.; Haynes, S.

2017-12-01

Regions of intermediate/deep water formation and water-mass mixing in the North Atlantic are poorly defined for the Late Cretaceous, a time of gateway evolution and cooler conditions following the Mid Cretaceous greenhouse. Improved proxy data combined with modeling efforts are required to effectively evaluate the relationship between CO2, paleogeography, and circulation during this cooler interval. We analyzed and compiled latest Cretaceous (79 - 66 Ma) ɛNd and δ13C records from seven bathyal (paleodepths 0.2 - 2 km) and eight abyssal (paleodepths > 2 km) sites in the North Atlantic. Data suggest local downwelling of Northern Component Water (NCW; ɛNd -9.5 and δ13C 1.7 ‰) is the primary source of intermediate/deep water masses in the basin. As this water flows southward and ages, δ13C values decrease and ɛNd values increase; however, additional chemical changes at several sites require mixing with contributions from several additional water masses. Lower ɛNd ( -10) and higher δ13C ( 1.9 ‰) values in the deep NW part of the basin indicate proximal contributions from a region draining old continental crust, potentially representing deep convection following opening of the Labrador Sea. In the deep NE Iberian Basin, higher ɛNd ( -7) and lower δ13C ( 0.8 ‰) during the Campanian suggest mixing with a Tethyan source (ɛNd -7 and δ13C 0.1 ‰) whose importance decreased with restriction of that gateway in the Maastrichtian. Data from bathyal sites suggest additional mixing. In the SE Cape Verde region, observed ɛNd variations from -10 in the Campanian to -13 and -12 in the early and late Maastrichtian, respectively, may record variations in output rates of Tethyan and/or NCW sources and Demerara Bottom Water (ɛNd -16), a proposed warm saline intermediate water mass formed in shallow, equatorial seas. Pacific inflow through the Caribbean gateway impacts intermediate sites at Blake Nose (ɛNd values -8), particularly the shallowest site during the late

The Importance of Conducting Life Sciences Experiments on the Deep Space Gateway Platform

NASA Astrophysics Data System (ADS)

Bhattacharya, S.

2018-02-01

Life science research on the Deep Space Gateway platform is an important precursor for long term human exploration of deep space. Ideas for utilizing flight hardware and well characterized model organisms will be discussed.

“Puerto Rico: gateway to landscape” from an ecological perspective

Treesearch

Grizelle Gonzalez

2015-01-01

The exhibit Puerto Rico: Gateway to Landscape proposes to explore various ways in which citizens approach the landscape, or construct it – inside and outside the city – and considers city planning, the creation of parks and natural reserves, and their interpretation. From a perspective of citizen involvement, this thematic scaffolding related to landscape and the...

Tobacco, the Common Enemy and a Gateway Drug: Policy Implications

ERIC Educational Resources Information Center

Torabi, Mohammad R.; Jun, Mi Kyung; Nowicke, Carole; Seitz de Martinez, Barbara; Gassman, Ruth

2010-01-01

For the four leading causes of death in the United States (heart disease, cancer, stroke and chronic respiratory disease), tobacco use is a common risk factor. Tobacco use is responsible for almost 450,000 deaths per year and impacts the health of every member of our society. Tobacco is a gateway drug for substance abuse. That role is critical to…

Construction of two Lactococcus lactis expression vectors combining the Gateway and the NIsin Controlled Expression systems.

PubMed

Douillard, François P; Mahony, Jennifer; Campanacci, Valérie; Cambillau, Christian; van Sinderen, Douwe

2011-09-01

Over the last 10 years, the NIsin Controlled Expression (NICE) system has been extensively used in the food-grade bacterium Lactococcus lactis subsp. cremoris to produce homologous and heterologous proteins for academic and biotechnological purposes. Although various L. lactis molecular tools have been developed, no expression vectors harboring the popular Gateway recombination system are currently available for this widely used cloning host. In this study, we constructed two expression vectors that combine the NICE and the Gateway recombination systems and we tested their applicability by recombining and over-expressing genes encoding structural proteins of lactococcal phages Tuc2009 and TP901-1. Over-expressed phage proteins were analyzed by immunoblotting and purified by His-tag affinity chromatography with protein productions yielding 2.8-3.7 mg/l of culture. This therefore is the first description of L. lactis NICE expression vectors which integrate the Gateway cloning technology and which are suitable for the production of sufficient amounts of proteins to facilitate subsequent structural and functional analyses. Copyright © 2011 Elsevier Inc. All rights reserved.

The scientific consensus on climate change as a gateway belief: experimental evidence.

PubMed

van der Linden, Sander L; Leiserowitz, Anthony A; Feinberg, Geoffrey D; Maibach, Edward W

2015-01-01

There is currently widespread public misunderstanding about the degree of scientific consensus on human-caused climate change, both in the US as well as internationally. Moreover, previous research has identified important associations between public perceptions of the scientific consensus, belief in climate change and support for climate policy. This paper extends this line of research by advancing and providing experimental evidence for a "gateway belief model" (GBM). Using national data (N = 1104) from a consensus-message experiment, we find that increasing public perceptions of the scientific consensus is significantly and causally associated with an increase in the belief that climate change is happening, human-caused and a worrisome threat. In turn, changes in these key beliefs are predictive of increased support for public action. In short, we find that perceived scientific agreement is an important gateway belief, ultimately influencing public responses to climate change.

The Scientific Consensus on Climate Change as a Gateway Belief: Experimental Evidence

PubMed Central

van der Linden, Sander L.; Leiserowitz, Anthony A.; Feinberg, Geoffrey D.; Maibach, Edward W.

2015-01-01

There is currently widespread public misunderstanding about the degree of scientific consensus on human-caused climate change, both in the US as well as internationally. Moreover, previous research has identified important associations between public perceptions of the scientific consensus, belief in climate change and support for climate policy. This paper extends this line of research by advancing and providing experimental evidence for a “gateway belief model” (GBM). Using national data (N = 1104) from a consensus-message experiment, we find that increasing public perceptions of the scientific consensus is significantly and causally associated with an increase in the belief that climate change is happening, human-caused and a worrisome threat. In turn, changes in these key beliefs are predictive of increased support for public action. In short, we find that perceived scientific agreement is an important gateway belief, ultimately influencing public responses to climate change. PMID:25714347

Flood risk and insurance loss potential in the Thames Gateway

NASA Astrophysics Data System (ADS)

Eldridge, J.; Horn, D.

2009-04-01

The Thames Gateway, currently Europe's largest regeneration project, is an area of redevelopment located in the South East of England, with Government plans to create up to 160,000 new homes and 180,000 new jobs by 2016. Although the new development is intended to contribute £12bn annually to the economy, the potential flood risk is high, with much of the area situated on Thames tidal floodplain and vulnerable to both storm surges and peak river flows. This poses significant hazard to those inhabiting the area and has raised concern amongst the UK insurance industry, who would be liable for significant financial claims if a large flood event were to occur, particularly with respect to the number of new homes and businesses being built in flood risk areas. Flood risk and the potential damage to both lives and assets in vulnerable areas have gained substantial recognition, in light of recent flooding events, from both governmental agencies and in the public's awareness of flood hazard. This has resulted in a change in UK policy with planning policy for flood risk (PPS25, Planning Policy Statement 25) adopting a more strategic approach to development, as well as a new Flooding and Water Bill which is due for consultation in 2009. The Government and the Association of British Insurers, who represent the UK insurance industry, have also recently changed their Statement of Principles which guides provision of flood insurance in the future. This PhD research project aims to quantify flood risk in the Thames Gateway area with a view to evaluating the insurance loss potential under different insurance and planning scenarios. Using current sources of inundation extent, and incorporating varying insurance penetration rates and degrees of adoption of planning policy and guidance, it focuses on estimating flood risk under these different scenarios. This presentation introduces the development of the project and the theory and methodology which will be used to address the

EAC and the Development of National and European Gateways to Archives

ERIC Educational Resources Information Center

Ottosson, Per-Gunnar

2005-01-01

In the development of gateways to archives there are two different approaches, one focusing on the descriptions of the material and the other on the creators. Search and retrieval with precision and quality require controlled access points and name authority control. National registries of private archives have a long tradition in implementing the…

The Case for Intentionally Interwoven Peer Learning Supports in Gateway-Course Improvement Efforts

ERIC Educational Resources Information Center

Dvorak, Johanna; Tucker, Kathryn

2017-01-01

This chapter describes how peer learning support programs can be used to improve learning and success in gateway courses. It provides examples from two institutions to further illustrate how this promising approach can improve student outcomes.

Bibliographic Post-Processing with the TIS Intelligent Gateway: Analytical and Communication Capabilities.

ERIC Educational Resources Information Center

Burton, Hilary D.

TIS (Technology Information System) is an intelligent gateway system capable of performing quantitative evaluation and analysis of bibliographic citations using a set of Process functions. Originally developed by Lawrence Livermore National Laboratory (LLNL) to analyze information retrieved from three major federal databases, DOE/RECON,…

Evaluation of the Gateway Monument Demonstration Program: Safety, Economic and Social Impact Analysis

DOT National Transportation Integrated Search

2009-09-01

The Gateway Monument Demonstration Program (GMDP) facilitated the construction of freestanding structures or signage along roadways to communicate the name of a city, county or township to motorists. The GMDP spanned a four-year period, commencing on...

The VERCE Science Gateway: Enabling User Friendly HPC Seismic Wave Simulations.

NASA Astrophysics Data System (ADS)

Casarotti, E.; Spinuso, A.; Matser, J.; Leong, S. H.; Magnoni, F.; Krause, A.; Garcia, C. R.; Muraleedharan, V.; Krischer, L.; Anthes, C.

2014-12-01

The EU-funded project VERCE (Virtual Earthquake and seismology Research Community in Europe) aims to deploy technologies which satisfy the HPC and data-intensive requirements of modern seismology.As a result of VERCE official collaboration with the EU project SCI-BUS, access to computational resources, like local clusters and international infrastructures (EGI and PRACE), is made homogeneous and integrated within a dedicated science gateway based on the gUSE framework. In this presentation we give a detailed overview on the progress achieved with the developments of the VERCE Science Gateway, according to a use-case driven implementation strategy. More specifically, we show how the computational technologies and data services have been integrated within a tool for Seismic Forward Modelling, whose objective is to offer the possibility to performsimulations of seismic waves as a service to the seismological community.We will introduce the interactive components of the OGC map based web interface and how it supports the user with setting up the simulation. We will go through the selection of input data, which are either fetched from federated seismological web services, adopting community standards, or provided by the users themselves by accessing their own document data store. The HPC scientific codes can be selected from a number of waveform simulators, currently available to the seismological community as batch tools or with limited configuration capabilities in their interactive online versions.The results will be staged out via a secure GridFTP transfer to a VERCE data layer managed by iRODS. The provenance information of the simulation will be automatically cataloged by the data layer via NoSQL techonologies.Finally, we will show the example of how the visualisation output of the gateway could be enhanced by the connection with immersive projection technology at the Virtual Reality and Visualisation Centre of Leibniz Supercomputing Centre (LRZ).

US Gateway to SIMBAD Astronomical Database

NASA Technical Reports Server (NTRS)

Eichhorn, G.; Oliversen, R. (Technical Monitor)

1999-01-01

During the last year the US SIMBAD Gateway Project continued to provide services like user registration to the US users of the SIMBAD database in France. Currently there are over 3400 US users registered. We also provide user support by answering questions from users and handling requests for lost passwords when still necessary. We have implemented in cooperation with the CDS SIMBAD project access to the SIMBAD database for US users on an Internet address basis. This allows most US users to access SIMBAD without having to enter passwords. We have maintained the mirror copy of the SIMBAD database on a server at SAO. This has allowed much faster access for the US users. We also supported a demonstration of the SIMBAD database at the meeting of the American Astronomical Society in January. We shipped computer equipment to the meeting and provided support for the demonstration activities at the SIMBAD booth. We continued to improve the cross-linking between the SIMBAD project and the Astrophysics Data System. This cross-linking between these systems is very much appreciated by the users of both the SIMBAD database and the ADS Abstract Service. The mirror of the SIMBAD database at SAO makes this connection faster for the US astronomers. We exchange information between the ADS and SIMBAD on a daily basis. The close cooperation between the CDS in Strasbourg and SAO, facilitated by this project, is an important part of the astronomy-wide digital library initiative called Urania. It has proven to be a model in how different data centers can collaborate and enhance the value of their products by linking with other data centers.

Integrating QoS and security functions in an IP-VPN gateway

NASA Astrophysics Data System (ADS)

Fan, Kuo-Pao; Chang, Shu-Hsin; Lin, Kuan-Ming; Pen, Mau-Jy

2001-10-01

IP-based Virtual Private Network becomes more and more popular. It can not only reduce the enterprise communication cost but also increase the revenue of the service provider. The common IP-VPN application types include Intranet VPN, Extranet VPN, and remote access VPN. For the large IP-VPN market, some vendors develop dedicated IP-VPN devices; while some vendors add the VPN functions into their existing network equipment such as router, access gateway, etc. The functions in the IP-VPN device include security, QoS, and management. The common security functions supported are IPSec (IP Security), IKE (Internet Key Exchange), and Firewall. The QoS functions include bandwidth control and packet scheduling. In the management component, policy-based network management is under standardization in IETF. In this paper, we discuss issues on how to integrate the QoS and security functions in an IP-VPN Gateway. We propose three approaches to do this. They are (1) perform Qos first (2) perform IPSec first and (3) reserve fixed bandwidth for IPSec. We also compare the advantages and disadvantages of the three proposed approaches.

A case study of the Secure Anonymous Information Linkage (SAIL) Gateway: A privacy-protecting remote access system for health-related research and evaluation☆

PubMed Central

Jones, Kerina H.; Ford, David V.; Jones, Chris; Dsilva, Rohan; Thompson, Simon; Brooks, Caroline J.; Heaven, Martin L.; Thayer, Daniel S.; McNerney, Cynthia L.; Lyons, Ronan A.

2014-01-01

With the current expansion of data linkage research, the challenge is to find the balance between preserving the privacy of person-level data whilst making these data accessible for use to their full potential. We describe a privacy-protecting safe haven and secure remote access system, referred to as the Secure Anonymised Information Linkage (SAIL) Gateway. The Gateway provides data users with a familiar Windows interface and their usual toolsets to access approved anonymously-linked datasets for research and evaluation. We outline the principles and operating model of the Gateway, the features provided to users within the secure environment, and how we are approaching the challenges of making data safely accessible to increasing numbers of research users. The Gateway represents a powerful analytical environment and has been designed to be scalable and adaptable to meet the needs of the rapidly growing data linkage community. PMID:24440148

Deep Space Gateway - Enabling Missions to Mars

NASA Technical Reports Server (NTRS)

Rucker, Michelle; Connolly, John

2017-01-01

There are many opportunities for commonality between Lunar vicinity and Mars mission hardware and operations. Best approach: Identify Mars mission risks that can be bought down with testing in the Lunar vicinity, then explore hardware and operational concepts that work for both missions with minimal compromise. Deep Space Transport will validate the systems and capabilities required to send humans to Mars orbit and return to Earth. Deep Space Gateway provides a convenient assembly, checkout, and refurbishment location to enable Mars missions Current deep space transport concept is to fly missions of increasing complexity: Shakedown cruise, Mars orbital mission, Mars surface mission; Mars surface mission would require additional elements.

Efficacy of a Summer Intervention to Improve GATEWAY Mathematics Examination Scores

ERIC Educational Resources Information Center

Jackson, Arthur Wesley

2011-01-01

Less than 50% of students from an inner-city high school in a southeastern US state who took the GATEWAY mathematics exam (2001-2007) earned a passing score on the first attempt, prompting teachers at the school to begin a summer intervention program based on Bandura's Self Efficacy Theory, to help them succeed on a subsequent reexamination. The…

Characterization of Outer Space Radiation Induced Changes in Extremophiles Utilizing Deep Space Gateway Opportunities

NASA Astrophysics Data System (ADS)

Venkateswaran, K.; Wang, C.; Smith, D.; Mason, C.; Landry, K.; Rettberg, P.

2018-02-01

Extremophilic microbial survival, adaptation, biological functions, and molecular mechanisms associated with outer space radiation can be tested by exposing them onto Deep Space Gateway hardware (inside/outside) using microbiology and molecular biology techniques.

America's freight transportation gateways : connecting our nation to places and markets abroad : [2009

DOT National Transportation Integrated Search

2009-11-01

This report ranks freight gateways by the value of merchandise trade they handle. Value : data were compiled from multiple sources, allowing comparison of all the freight modes. : See box 2 for a detailed description of the freight data sources. : Th...

Sensitivity of climate and Atlantic overturning circulation to uncertain ocean gateway configurations for the late Miocene

NASA Astrophysics Data System (ADS)

Bradshaw, C.; Lunt, D. J.; Flecker, R.; Martinez-Mendez, G.

2013-12-01

The palaeorecord documents late Miocene (11.6-5.3 Ma) climate to be much warmer and wetter than today yet CO2 reconstructions are similar to modern levels. Given the apparent decoupling between CO2 and warmth for this period we investigate here the role of the oceans. The late Miocene experienced significant tectonic change including the restriction of some of the last ocean gateways to close (Panama Gateway and Indonesian Seaway) and open (Bering Strait and Barents/Kara Sea). However, the timing and configuration of these tectonic changes is uncertain. The final closure of the Panama Gateway is dated to the Pliocene, but continental mammal exchange suggests the existence of a Central American archipelago from the mid-late Miocene. The Bering Strait is typically assumed to have opened at the very end of the late Miocene/early Pliocene based on diatom exchange, but other marine and terrestrial evidence points to a much earlier, perhaps intermittent, opening. The timing of the restriction of the Indonesian Seaway is very poorly constrained at middle Miocene to Pliocene. The Barents Sea and Kara Sea shelves are documented as having being subject to extensive glacial erosion and post-glacial uplift since the Pliocene and throughout the Quaternary but records of uplift and erosion during the earlier Cenozoic are limited. However, the presence of significant preglacial sediments suggests that this region underwent tectonic uplift, volcanism and subsequent erosion during the Eocene-Miocene period although the age assignment of the data remains controversial. The Panama Gateway has been suggested to influence North Atlantic Deep Water (NADW) production through numerous modelling studies, the Bering Strait has been suggested to greatly impact NADW during the Quaternary, and the strength of Indonesian Throughflow is hypothesised to influence Agulhas Leakage, which, in turn, has been speculated to influence Atlantic meridional overturning and thus NADW production. Here, we

Common liability to addiction and “gateway hypothesis”: Theoretical, empirical and evolutionary perspective

PubMed Central

Vanyukov, Michael M.; Tarter, Ralph E.; Kirillova, Galina P.; Kirisci, Levent; Reynolds, Maureen D.; Kreek, Mary Jeanne; Conway, Kevin P.; Maher, Brion S.; Iacono, William G.; Bierut, Laura; Neale, Michael C.; Clark, Duncan B.; Ridenour, Ty A.

2013-01-01

Background Two competing concepts address the development of involvement with psychoactive substances: the “gateway hypothesis” (GH) and common liability to addiction (CLA). Method The literature on theoretical foundations and empirical findings related to both concepts is reviewed. Results The data suggest that drug use initiation sequencing, the core GH element, is variable and opportunistic rather than uniform and developmentally deterministic. The association between risks for use of different substances, if any, can be more readily explained by common underpinnings than by specific staging. In contrast, the CLA concept is grounded in genetic theory and supported by data identifying common sources of variation in the risk for specific addictions. This commonality has identifiable neurobiological substrate and plausible evolutionary explanations. Conclusions Whereas the “gateway” hypothesis does not specify mechanistic connections between “stages”, and does not extend to the risks for addictions, the concept of common liability to addictions incorporates sequencing of drug use initiation as well as extends to related addictions and their severity, provides a parsimonious explanation of substance use and addiction co-occurrence, and establishes a theoretical and empirical foundation to research in etiology, quantitative risk and severity measurement, as well as targeted non-drug-specific prevention and early intervention. PMID:22261179

A case study of the Secure Anonymous Information Linkage (SAIL) Gateway: a privacy-protecting remote access system for health-related research and evaluation.

PubMed

Jones, Kerina H; Ford, David V; Jones, Chris; Dsilva, Rohan; Thompson, Simon; Brooks, Caroline J; Heaven, Martin L; Thayer, Daniel S; McNerney, Cynthia L; Lyons, Ronan A

2014-08-01

With the current expansion of data linkage research, the challenge is to find the balance between preserving the privacy of person-level data whilst making these data accessible for use to their full potential. We describe a privacy-protecting safe haven and secure remote access system, referred to as the Secure Anonymised Information Linkage (SAIL) Gateway. The Gateway provides data users with a familiar Windows interface and their usual toolsets to access approved anonymously-linked datasets for research and evaluation. We outline the principles and operating model of the Gateway, the features provided to users within the secure environment, and how we are approaching the challenges of making data safely accessible to increasing numbers of research users. The Gateway represents a powerful analytical environment and has been designed to be scalable and adaptable to meet the needs of the rapidly growing data linkage community. Copyright © 2014 The Aurthors. Published by Elsevier Inc. All rights reserved.

A gateway for phylogenetic analysis powered by grid computing featuring GARLI 2.0.

PubMed

Bazinet, Adam L; Zwickl, Derrick J; Cummings, Michael P

2014-09-01

We introduce molecularevolution.org, a publicly available gateway for high-throughput, maximum-likelihood phylogenetic analysis powered by grid computing. The gateway features a garli 2.0 web service that enables a user to quickly and easily submit thousands of maximum likelihood tree searches or bootstrap searches that are executed in parallel on distributed computing resources. The garli web service allows one to easily specify partitioned substitution models using a graphical interface, and it performs sophisticated post-processing of phylogenetic results. Although the garli web service has been used by the research community for over three years, here we formally announce the availability of the service, describe its capabilities, highlight new features and recent improvements, and provide details about how the grid system efficiently delivers high-quality phylogenetic results. © The Author(s) 2014. Published by Oxford University Press, on behalf of the Society of Systematic Biologists.

Social class culture cycles: how three gateway contexts shape selves and fuel inequality.

PubMed

Stephens, Nicole M; Markus, Hazel Rose; Phillips, L Taylor

2014-01-01

America's unprecedented levels of inequality have far-reaching negative consequences for society as a whole. Although differential access to resources contributes to inequality, the current review illuminates how ongoing participation in different social class contexts also gives rise to culture-specific selves and patterns of thinking, feeling, and acting. We integrate a growing body of interdisciplinary research to reveal how social class culture cycles operate over the course of the lifespan and through critical gateway contexts, including homes, schools, and workplaces. We first document how each of these contexts socializes social class cultural differences. Then, we demonstrate how these gateway institutions, which could provide access to upward social mobility, are structured according to middle-class ways of being a self and thus can fuel and perpetuate inequality. We conclude with a discussion of intervention opportunities that can reduce inequality by taking into account the contextual responsiveness of the self.

Flooding and subsidence in the Thames Gateway: impact on insurance loss potential

NASA Astrophysics Data System (ADS)

Royse, Katherine; Horn, Diane; Eldridge, Jillian; Barker, Karen

2010-05-01

In the UK, household buildings insurance generally covers loss and damage to the insured property from a range of natural and human perils, including windstorm, flood, subsidence, theft, accidental fire and winter freeze. Consequently, insurers require a reasoned view on the likely scale of losses that they may face to assist in strategic planning, reinsurance structuring, regulatory returns and general risk management. The UK summer 2007 flood events not only provided a clear indication of the scale of potential losses that the industry could face from an individual event, with £3 billion in claims, but also identified a need for insurers and reinsurers to better understand how events may correlate in time and space, and how to most effectively use the computational models of extreme events that are commonly applied to reflect these correlations. In addition to the potential for temporal clustering of events such as windstorms and floods, there is a possibility that seemingly uncorrelated natural perils, such as floods and subsidence, may impact an insurer's portfolio. Where aggregations of large numbers of new properties are planned, such as in the Thames Gateway, consideration of the potential future risk of aggregate losses due to the combination of perils such as subsidence and flood is increasingly important within the insurance company's strategic risk management process. Whilst perils such as subsidence and flooding are generally considered independent within risk modelling, the potential for one event to influence the magnitude and likelihood of the other should be taken into account when determining risk level. In addition, the impact of correlated, but distinctive, loss causing events on particular property types may be significant, particularly if a specific property is designed to protect against one peril but is potentially susceptible to another. We suggest that flood events can lead to increased subsidence risk due to the weight of additional water

GateWay Community College Water Resources Program Partnerships: An Opportunity for Program Success and Collaboration

NASA Astrophysics Data System (ADS)

Castaneda, M.

2012-12-01

GateWay Community College Water Resources Technologies (WRT) Program offers Certificate of Completions and Associate Degrees on Hydrologic Studies, Water Treatment and Wastewater Treatment. The program has been in existence since 1998 and has gone through several updates to meet the demand for professionals in those areas. The program includes theoretical and practical hands-on training in the monitoring of water quality and quantity as well as in water and industrial wastewater treatment. The WRT program offers online, face-to-face, and hybrid courses to address different student's needs for training. The program only Full-time faculty is supported by 15 adjunct- faculty professionals. Adjunct faculty is usually hired from a wide variety of professional people already working in the industry that have shown interest on teaching. Adjunct faculty also provide free tutoring to the WRT students when they are not teaching courses. The college Learning Center provides funding to support these tutoring activities. The program has an active Advisory Committee that provides guidance and recommends program changes to meet their training needs. This Advisory Committee is made of professionals from different federal, state, county agencies, and municipalities, private industry and consulting companies in the area. The Advisory Committee meets every year to provide feedback to GateWay on curriculum changes and commit to potential internship opportunities for the WRT students. Those internships (or voluntary work) are paid directly by the municipalities or agencies or can be paid by the GateWay WRT program. These internship jobs provides with an opportunity to actively promote the WRT program throughout the valley. The GateWay WRT program considers the Advisory Committee an essential component for the program success: the committee supports the program in recommending and acquiring the latest field equipment needed for the hands-on training. One of the main WRT program

GATEWAY Report Brief: Tunable-White Lighting at the ACC Care Center

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

Summary of a GATEWAY program report that documented the performance of tunable-white LED lighting systems installed in several spaces within the ACC Care Center, a senior-care facility in Sacramento, CA. The project results included energy savings and improved lighting quality, as well as other possible health-related benefits that may have been attributable, at least in part, to the lighting changes.

Gateways to Understanding: A Model for Exploring and Discerning Meaning from Experience

ERIC Educational Resources Information Center

Mears, Carolyn Lunsford

2008-01-01

Qualitative research methodologies comprise distinct traditions, each of which is based on its own assumptions and discrete methods for collecting, analyzing and reporting data. This paper examines a distinctive approach to qualitative research that was employed in a recent study to open a gateway to understanding the impact of the shootings at…

Enabling Global Lunar Sample Return and Life-Detection Studies Using a Deep-Space Gateway

NASA Astrophysics Data System (ADS)

Cohen, B. A.; Eigenbrode, J. A.; Young, K. E.; Bleacher, J. E.; Trainer, M. E.

2018-02-01

The Deep Space Gateway could uniquely enable a lunar robotic sampling campaign that would provide incredible science return as well as feed forward to Mars and Europa by testing instrument sterility and ability to distinguish biogenic signals.

US Gateway to SIMBAD Astronomical Database

NASA Technical Reports Server (NTRS)

Eichhorn, G.

1998-01-01

During the last year the US SIMBAD Gateway Project continued to provide services like user registration to the US users of the SIMBAD database in France. User registration is required by the SIMBAD project in France. Currently, there are almost 3000 US users registered. We also provide user support by answering questions from users and handling requests for lost passwords. We have worked with the CDS SIMBAD project to provide access to the SIMBAD database to US users on an Internet address basis. This will allow most US users to access SIMBAD without having to enter passwords. This new system was installed in August, 1998. The SIMBAD mirror database at SAO is fully operational. We worked with the CDS to adapt it to our computer system. We implemented automatic updating procedures that update the database and password files daily. This mirror database provides much better access to the US astronomical community. We also supported a demonstration of the SIMBAD database at the meeting of the American Astronomical Society in January. We shipped computer equipment to the meeting and provided support for the demonstration activities at the SIMBAD booth. We continued to improve the cross-linking between the SIMBAD project and the Astro- physics Data System. This cross-linking between these systems is very much appreciated by the users of both the SIMBAD database and the ADS Abstract Service. The mirror of the SIMBAD database at SAO makes this connection faster for the US astronomers. The close cooperation between the CDS in Strasbourg and SAO, facilitated by this project, is an important part of the astronomy-wide digital library initiative called Urania. It has proven to be a model in how different data centers can collaborate and enhance the value of their products by linking with other data centers.

Success in Gateway Business Courses: What Matters and What Can We Do?

ERIC Educational Resources Information Center

Berry, Tom; Cook, Lori; Hill, Nancy Thorley; Stevens, Kevin T.

2013-01-01

Introductory business classes, particularly those with a quantitative emphasis, can often serve as a barrier to students rather than as a gateway. This study looks at how study skills, aptitude, and external factors affect classroom performance. We examine whether, when, how, and how much students read their textbook. We also look at selected deep…

Lunar Heat Flux Measurements Enabled by a Microwave Radiometer Aboard the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Siegler, M.; Ruf, C.; Putzig, N.; Morgan, G.; Hayne, P.; Paige, D.; Nagihara, S.; Weber, R.

2018-02-01

We would like to present a concept to use the Deep Space Gateway as a platform for constraining the geothermal heat production, surface, and near-surface rocks, and dielectric properties of the Moon from orbit with passive microwave radiometery.

Basic and Applied Algal Life Support System Research on Board the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Niederwieser, T.; Zea, L.; Anthony, J.; Stodieck, L.

2018-02-01

We study the effect of long-term preservation methods on DNA damage of algal cultures for BLSS applications. In a secondary step, the Deep Space Gateway serves as a technology demonstration platform for algal photobioreactors in intermittently occupied habitats.

E-DECIDER Decision Support Gateway For Earthquake Disaster Response

NASA Astrophysics Data System (ADS)

Glasscoe, M. T.; Stough, T. M.; Parker, J. W.; Burl, M. C.; Donnellan, A.; Blom, R. G.; Pierce, M. E.; Wang, J.; Ma, Y.; Rundle, J. B.; Yoder, M. R.

2013-12-01

Earthquake Data Enhanced Cyber-Infrastructure for Disaster Evaluation and Response (E-DECIDER) is a NASA-funded project developing capabilities for decision-making utilizing remote sensing data and modeling software in order to provide decision support for earthquake disaster management and response. E-DECIDER incorporates earthquake forecasting methodology and geophysical modeling tools developed through NASA's QuakeSim project in order to produce standards-compliant map data products to aid in decision-making following an earthquake. Remote sensing and geodetic data, in conjunction with modeling and forecasting tools, help provide both long-term planning information for disaster management decision makers as well as short-term information following earthquake events (i.e. identifying areas where the greatest deformation and damage has occurred and emergency services may need to be focused). E-DECIDER utilizes a service-based GIS model for its cyber-infrastructure in order to produce standards-compliant products for different user types with multiple service protocols (such as KML, WMS, WFS, and WCS). The goal is to make complex GIS processing and domain-specific analysis tools more accessible to general users through software services as well as provide system sustainability through infrastructure services. The system comprises several components, which include: a GeoServer for thematic mapping and data distribution, a geospatial database for storage and spatial analysis, web service APIs, including simple-to-use REST APIs for complex GIS functionalities, and geoprocessing tools including python scripts to produce standards-compliant data products. These are then served to the E-DECIDER decision support gateway (http://e-decider.org), the E-DECIDER mobile interface, and to the Department of Homeland Security decision support middleware UICDS (Unified Incident Command and Decision Support). The E-DECIDER decision support gateway features a web interface that

An Assessment of the Adult Learners' Needs at Gateway Community-Technical College.

ERIC Educational Resources Information Center

Luna, Wilson

A study was conducted to assess the needs of adult learners at Gateway Community-Technical College (GCTC), in North Haven, Connecticut. An extended literature review resulted the choice of the three-part Adult Learner Needs Assessment Survey (ALNAS). In spring 1993, the ALNAS was administered to adult learners in classes at GCTC, resulting in 400…

Factors Affecting Student Academic Success in Gateway Courses at Northern Arizona University

ERIC Educational Resources Information Center

Benford, Russell; Gess-Newsome, Julie

2006-01-01

Students in gateway business, math, and science courses at Northern Arizona University receive non-passing grades (grades of D, F, and W) at high rates. To identify possible trends in demographic groups that receive DFWs and to investigate why students receive DFWs in these courses, a student survey was administered to 719 students in 7 gateway…

GATEWAY Demonstrations: OLED Lighting in the Offices of Aurora Lighting Design, Inc.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, Naomi J.

At the offices of Aurora Lighting Design, Inc., in Grayslake, IL, the GATEWAY program conducted its first investigation involving OLED lighting. The project experienced several challenges, but also highlighted a number of promising attributes – which indicate that with continued improvements in efficacy, longevity, size, and flexibility, OLEDs could provide a new tool for creative and effective lighting.

Low-Energy Cosmic Rays: Radiation Environment Studies and Astrophysics on the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Losekamm, M. J.; Berger, T.

2018-02-01

The Deep Space Gateway will be ideally located to investigate the cosmic radiation that astronauts are subjected to in deep space and to help shed light on one of the most intriguing astrophysical mysteries of today: What is the universe made of?

GATEWAY Demonstrations: OLED Lighting in the Offices of DeJoy, Knauf & Blood, LLP

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, Naomi J.

At the offices of the accounting firm of DeJoy, Knauf & Blood, LLP in Rochester, NY, the GATEWAY program evaluated a new lighting system that incorporates a number of different OLED luminaires. Evaluation of the OLED products included efficacy performance, field measurements of panel color, flicker measurements, and staff feedback.

Optical gateway for intelligent buildings: a new open-up window to the optical fibre sensors market?

NASA Astrophysics Data System (ADS)

Fernandez-Valdivielso, Carlos; Matias, Ignacio R.; Arregui, Francisco J.; Bariain, Candido; Lopez-Amo, Manuel

2004-06-01

This paper presents the first optical fiber sensor gateway for integrating these special measurement devices in Home Automation Systems, concretely in those buildings that use the KNX European Intelligent Buildings Standard.

Tactical Network Load Balancing in Multi-Gateway Wireless Sensor Networks

DTIC Science & Technology

2013-12-01

writeup scrsz = get( 0 ,’ScreenSize’); %Creation of the random Sensor Network fig = figure(1); set(fig, ’Position’,[1 scrsz( 4 )*.25 scrsz(3)*.7...thesis writeup scrsz = get( 0 ,’ScreenSize’); %Creation of the random Sensor Network fig = figure(1); set(fig, ’Position’,[1 scrsz( 4 )*.25 scrsz(3)*.7...TYPE AND DATES COVERED Master’s Thesis 4 . TITLE AND SUBTITLE TACTICAL NETWORK LOAD BALANCING IN MULTI-GATEWAY WIRELESS SENSOR NETWORKS 5

78 FR 47410 - General Management Plan, Draft Environmental Impact Statement, Gateway National Recreation Area...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-05

...] General Management Plan, Draft Environmental Impact Statement, Gateway National Recreation Area, New... (NPS) is releasing a Draft Environmental Impact Statement (DEIS) for the General Management Plan (GMP... alternatives to guide the management of the site over the next 20 years. The NPS preferred alternative...

Second Flexner Century: The Democratization of Medical Knowledge: Repurposing a General Pathology Course Into Multigrade-Level "Gateway" Courses.

PubMed

Weinstein, Ronald S; Waer, Amy L; Weinstein, John B; Briehl, Margaret M; Holcomb, Michael J; Erps, Kristine A; Holtrust, Angelette L; Tomkins, Julie M; Barker, Gail P; Krupinski, Elizabeth A

2017-01-01

Starting in 1910, the "Flexner Revolution" in medical education catalyzed the transformation of the US medical education enterprise from a proprietary medical school dominated system into a university-based medical school system. In the 21st century, what we refer to as the "Second Flexner Century" shifts focus from the education of medical students to the education of the general population in the "4 health literacies." Compared with the remarkable success of the first Flexner Revolution, retrofitting medical science education into the US general population today, starting with K-12 students, is a more daunting task. The stakes are high. The emergence of the patient-centered medical home as a health-care delivery model and the revelation that medical errors are the third leading cause of adult deaths in the United States are drivers of population education reform. In this century, patients will be expected to assume far greater responsibility for their own health care as full members of health-care teams. For us, this process began in the run-up to the "Second Flexner Century" with the creation and testing of a general pathology course, repurposed as a series of "gateway" courses on mechanisms of diseases, suitable for introduction at multiple insertion points in the US education continuum. In this article, we describe nomenclature for these gateway courses and a "top-down" strategy for creating pathology coursework for nonmedical students. Finally, we list opportunities for academic pathology departments to engage in a national "Democratization of Medical Knowledge" initiative.

Using knowledge for indexing health web resources in a quality-controlled gateway.

PubMed

Joubert, Michel; Darmoni, Stefan J; Avillach, Paul; Dahamna, Badisse; Fieschi, Marius

2008-01-01

The aim of this study is to provide to indexers MeSH terms to be considered as major ones in a list of terms automatically extracted from a document. We propose a method combining symbolic knowledge - the UMLS Metathesaurus and Semantic Network - and statistical knowledge drawn from co-occurrences of terms in the CISMeF database (a French-language quality-controlled health gateway) using data mining measures. The method was tested on CISMeF corpus of 293 resources. There was a proportion of 0.37+/-0.26 major terms in the processed records. The method produced lists of terms with a proportion of terms initially pointed out as major of 0.54+/-0.31. The method we propose reduces the number of terms, which seem not useful for content description of resources, such as "check tags", but retains the most descriptive ones. Discarding these terms is accounted for by: 1) the removal by using semantic knowledge of associations of concepts bearing no real medical significance, 2) the removal by using statistical knowledge of nonstatistically significant associations of terms. This method can assist effectively indexers in their daily work and will be soon applied in the CISMeF system.

Physician Acceptance of Gateway to Care at Irwin Army Community Hospital

DTIC Science & Technology

1992-07-27

frontier cavalry post once commanded by General George Armstrong Custer. Today it is the home of almost 20,000 soldiers of the Big Red One, First Infantry...especially important for the future. Physicians, as key "players" in healthcare organizations, are also key to the success of Gateway to Care. Kotler and...research (3rd ed.). New York: Holt. Physician Acceptance 32 Kotler , P., & Clarke, R. (1987). Marketing for health care organizations. Englewood Cliffs

Baker-Barry Tunnel Lighting: Evaluation of a Potential GATEWAY Demonstrations Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tuenge, Jason R.

2011-06-01

The U.S. Department of Energy (DOE) is evaluating the Baker-Barry Tunnel as a potential GATEWAY Demonstrations project for deployment of solid-state lighting (SSL) technology. The National Park Service (NPS) views this project as a possible proving ground and template for implementation of light-emitting diode (LED) luminaires in other NPS tunnels, thereby expanding the estimated 40% energy savings from 132 MWh/yr for this tunnel to a much larger figure national

Seal of transparency heritage in the CISMeF quality-controlled health gateway

PubMed Central

Darmoni, SJ; Dahamna, B; Roth-Berghofer, Thomas R

2004-01-01

Background It is an absolute necessity to continually assess the quality of health information on the Internet. Quality-controlled subject gateways are Internet services which apply a selected set of targeted measures to support systematic resource discovery. Methods The CISMeF health gateway became a contributor to the MedCIRCLE project to evaluate 270 health information providers. The transparency heritage consists of using the evaluation performed on providers that are referenced in the CISMeF catalogue for evaluating the documents they publish, thus passing on the transparency label from the publishers to their documents. Results Each site rated in CISMeF has a record in the CISMeF database that generates an RDF into HTML file. The search tool Doc'CISMeF displays information originating from every publisher evaluated with a specific MedCIRCLE button, which is linked to the MedCIRCLE central repository. Starting with 270 websites, this trust heritage has led to 6,480 evaluated resources in CISMeF (49.8% of the 13,012 resources included in CISMeF). Conclusion With the MedCIRCLE project and transparency heritage, CISMeF became an explicit third party. PMID:15367332

A PICKSC Science Gateway for enabling the common plasma physicist to run kinetic software

NASA Astrophysics Data System (ADS)

Hu, Q.; Winjum, B. J.; Zonca, A.; Youn, C.; Tsung, F. S.; Mori, W. B.

2017-10-01

Computer simulations offer tremendous opportunities for studying plasmas, ranging from simulations for students that illuminate fundamental educational concepts to research-level simulations that advance scientific knowledge. Nevertheless, there is a significant hurdle to using simulation tools. Users must navigate codes and software libraries, determine how to wrangle output into meaningful plots, and oftentimes confront a significant cyberinfrastructure with powerful computational resources. Science gateways offer a Web-based environment to run simulations without needing to learn or manage the underlying software and computing cyberinfrastructure. We discuss our progress on creating a Science Gateway for the Particle-in-Cell and Kinetic Simulation Software Center that enables users to easily run and analyze kinetic simulations with our software. We envision that this technology could benefit a wide range of plasma physicists, both in the use of our simulation tools as well as in its adaptation for running other plasma simulation software. Supported by NSF under Grant ACI-1339893 and by the UCLA Institute for Digital Research and Education.

Linking Gateway Technical College with Workforce Development: The SC Johnson-A Family Company Story.

ERIC Educational Resources Information Center

Knudson, Edward

2004-01-01

Seven years ago, SC Johnson--A Family Company approached Gateway Technical College with a need to further strengthen their incumbent workforce's technical training and education. Retirements, brain drain, and competition for technical expertise were the forces driving SC Johnson to develop a comprehensive, flexible, and timely workplace education…

Lunar Global Heat Flow Mapping with a Reusable Lander Deployed from the Deep Space Gateway Spacecraft

NASA Astrophysics Data System (ADS)

Nagihara, S.; Zacny, K.; Chu, P.; Kiefer, W. S.

2018-02-01

We propose to equip the Deep Space Gateway spacecraft with a reusable lander that can shuttle to and from the lunar surface, and use it for collecting heat flow measurements globally on the lunar surface.

GATEWAY Demonstrations: Trial Demonstration of Area Lighting Retrofit, Yuma Border Patrol, Yuma, Arizona

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilkerson, A. M.; McCullough, J. J.

Along the Yuma Sector Border Patrol Area in Yuma, Arizona, the GATEWAY program conducted a trial demonstration in which the incumbent quartz metal halide area lighting was replaced with LED at three pole locations at the Yuma Sector Border Patrol Area in Yuma, Arizona. The retrofit was documented to better understand LED technology performance in high-temperature environments.

The Globus Galaxies Platform. Delivering Science Gateways as a Service

DOE Office of Scientific and Technical Information (OSTI.GOV)

Madduri, Ravi; Chard, Kyle; Chard, Ryan

We use public cloud computers to host sophisticated scientific data; software is then used to transform scientific practice by enabling broad access to capabilities previously available only to the few. The primary obstacle to more widespread use of public clouds to host scientific software (‘cloud-based science gateways’) has thus far been the considerable gap between the specialized needs of science applications and the capabilities provided by cloud infrastructures. We describe here a domain-independent, cloud-based science gateway platform, the Globus Galaxies platform, which overcomes this gap by providing a set of hosted services that directly address the needs of science gatewaymore » developers. The design and implementation of this platform leverages our several years of experience with Globus Genomics, a cloud-based science gateway that has served more than 200 genomics researchers across 30 institutions. Building on that foundation, we have also implemented a platform that leverages the popular Galaxy system for application hosting and workflow execution; Globus services for data transfer, user and group management, and authentication; and a cost-aware elastic provisioning model specialized for public cloud resources. We describe here the capabilities and architecture of this platform, present six scientific domains in which we have successfully applied it, report on user experiences, and analyze the economics of our deployments. Published 2015. This article is a U.S. Government work and is in the public domain in the USA.« less

Accessibility: global gateway to health literacy.

PubMed

Perlow, Ellen

2010-01-01

Health literacy, cited as essential to achieving Healthy People 2010's goals to "increase quality and years of healthy life" and to "eliminate health disparities," is defined by Healthy People as "the degree to which individuals have the capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions." Accessibility, by definition, the aforementioned "capacity to obtain," thus is health literacy's primary prerequisite. Accessibility's designation as the global gateway to health literacy is predicated also on life's realities: global aging and climate change, war and terrorism, and life-extending medical and technological advances. People with diverse access needs are health professionals' raison d'être. However, accessibility, consummately cross-cultural and universal, is virtually absent as a topic of health promotion and practice research and scholarly discussion of health literacy and equity. A call to action to place accessibility in its rightful premier position on the profession's agenda is issued.

Los Angeles-Gateway Freight Advanced Traveler Information System : final system design and architecture for FRATIS prototype.

DOT National Transportation Integrated Search

2013-05-01

This Final Architecture and Design report has been prepared to describe the structure and design of all the system components for the LA-Gateway FRATIS Demonstration Project. More specifically, this document provides: Detailed descriptions of the...

Smart home design for electronic devices monitoring based wireless gateway network using cisco packet tracer

NASA Astrophysics Data System (ADS)

Sihombing, Oloan; Zendrato, Niskarto; Laia, Yonata; Nababan, Marlince; Sitanggang, Delima; Purba, Windania; Batubara, Diarmansyah; Aisyah, Siti; Indra, Evta; Siregar, Saut

2018-04-01

In the era of technological development today, the technology has become the need for the life of today's society. One is needed to create a smart home in turning on and off electronic devices via smartphone. So far in turning off and turning the home electronic device is done by pressing the switch or remote button, so in control of electronic device control less effective. The home smart design is done by simulation concept by testing system, network configuration, and wireless home gateway computer network equipment required by a smart home network on cisco packet tracer using Internet Thing (IoT) control. In testing the IoT home network wireless network gateway system, multiple electronic devices can be controlled and monitored via smartphone based on predefined configuration conditions. With the Smart Ho me can potentially increase energy efficiency, decrease energy usage costs, control electronics and change the role of residents.

Community Colleges as Gateways and Gatekeepers: Moving beyond the Access "Saga" toward Outcome Equity

ERIC Educational Resources Information Center

Dowd, Alicia C.

2007-01-01

Community colleges are essential--though often overlooked--institutions of higher education. In this essay, Alicia C. Dowd draws attention to the challenges facing community colleges as they seek to balance their roles as both gateways and gatekeepers with their multiple missions, which include meeting the diverse needs of students at the…

A Squandered Resource: The Divestment of Mexican Parental Involvement in a New Gateway State

ERIC Educational Resources Information Center

Petrone, Eleanor

2016-01-01

Parental involvement plays an important role in the academic success of children. Schools in new gateway states where there has not been a longstanding tradition of immigration often lack the cultural knowledge and linguistic resources necessary to serve immigrant youth and their families effectively. By examining the experiences of Mexican…

Impact of Northern Hemisphere polar gateways on the Arctic Ocean climate during the latest Cretaceous as simulated by an Earth System Model.

NASA Astrophysics Data System (ADS)

Niezgodzki, Igor; Knorr, Gregor; Lohmann, Gerrit; Tyszka, Jarosław

2017-04-01

Using the Earth System Model COSMOS, we simulate the Late Cretaceous climate with different gateway configurations in the Arctic Ocean region under constant CO2 level of 1120 ppm (4 x pre-industrial). Based on the Maastrichtian paleogeography, we modify gateway configurations in the Arctic region according to different scenarios recorded from the Campanian - Maastrichtian ( 83-66 Ma). Our simulation with the Greenland-Norwegian Sea even as deep as 1.5 km in the Campanian produces consistent salinities in the Greenland-Norwegian Sea and in the surface Arctic Ocean, with the proxy-based salinity reconstructions. Towards the end of the Maastrichtian the gateway became shallower but didn't close entirely before the K-Pg boundary. During entire interval, the simulated salinity in the Arctic Ocean was well stratified, in agreement with the data. The surface ocean became progressively fresher, starting from the moderately brackish conditions in the Campanian to the (almost) freshwater conditions around the K-Pg boundary. Arctic gateways configuration changes cannot reproduce cooling trends as reconstructed by the proxy data during the Campanian - Maastrichtian interval. Our additional sensitivity tests with the different CO2 levels (1-6 x pre-industrial) and fixed (Maastrichtian) paleogeography show that a doubling of atmospheric CO2 concentration from 560 ppm to 1120 ppm results in an increase in the zonal mean surface air temperature in the polar regions by as high as 10°C. This suggests that the CO2 level decline, rather than gateway configuration changes, was responsible for the cooling trend toward the end of the Maastrichtian. The research was supported from the grant of the National Science Center in Poland based on the decision DEC-2012/07/N/ST10/03419.

Los Angeles-Gateway Freight Advanced Traveler Information System : prototype development and small-scale demonstrations for FRATIS.

DOT National Transportation Integrated Search

2013-06-01

This Demonstration Plan has been prepared to provide guidance and a common definition to all parties of the testing program that will be conducted for the LA-Gateway FRATIS Demonstration Project. More specifically, this document provides: Plannin...

76 FR 18294 - Receipt of Noise Compatibility Program and Request for Review; Kissimmee Gateway Airport...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-01

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Receipt of Noise Compatibility... reviewing a proposed Noise Compatibility Program that was submitted for Kissimmee Gateway Airport under the provisions of 49 U.S.C. 47504 et seq. (the Aviation Safety and Noise Abatement Act hereinafter referred to as...

Pre-Assessment and Peer Tutoring as Measures to Improve Performance in Gateway General Chemistry Classes

ERIC Educational Resources Information Center

Allenbaugh, R. J.; Herrera, K. M.

2014-01-01

Determining student readiness for gateway chemistry courses and providing underprepared students effective remediation are important as student bodies are growing increasingly diverse in their precollege preparation. The effectiveness of the ACT Mathematics Test and the Whimbey Analytical Skills Inventory (WASI) in predicting student success in…

Utilizing the Deep Space Gateway to Characterize DNA Damage Due to Space Radiation and Repair Mechanisms

NASA Astrophysics Data System (ADS)

Zea, L.; Niederwieser, T.; Anthony, J.; Stodieck, L.

2018-02-01

The radiation environment experienced in the Deep Space Gateway enables the interrogation of DNA damage and repair mechanisms, which may serve to determine the likelihood and consequence of the high radiation risk to prolonged human presence beyond LEO.

Out of the Depths Have I Cried: Aesthetic Opposition at the Gateway to Auschwitz

ERIC Educational Resources Information Center

Javore, Barbara B.

2015-01-01

Terezin, the gateway to Auschwitz, a town commandeered by the Nazis to serve as a "model" relocation camp to demonstrate the Third Reich's generosity and kindness toward the Jews, was an elaborate hoax. In an environment where truth was twisted beyond recognition, artists, writers, actors, and musicians used their work to revive the…

Gateways to clinical trials.

PubMed

Bayes, M; Rabasseda, X; Prous, J R

2003-06-01

Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Studies knowledge area of Prous Science Integrity(R), the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: AdGVVEGF121.10, anakinra, andolast, anidulafungin, APC-2059, l-arginine hydrochloride, aripiprazole, arzoxifene hydrochloride, asimadoline; Bexarotene, bimatoprost, bimosiamose, bizelesin, BMS-188667, botulinum toxin type B, bromfenac sodium, bryostatin 1; Cannabidiol, cariporide mesilate, CCI-1004, CDP-571, cerivastatin sodium, clevudine; Dalbavancin, darbepoetin alfa, decitabine, deligoparin sodium, diethylnorspermine, drotrecogin alfa (activated), DTaP-HBV-IPV/Hib-vaccine; E-5564, eculizumab, edodekin alfa, emtricitabine, enfuvirtide, (-)-epigallocatechin gallate, eplerenone, esomeprazole magnesium, etaquine, etoricoxib, ezetimibe; Fesoterodine, fipamezole hydrochloride, fondaparinux sodium, fosamprenavir calcium, frovatriptan, fulvestrant; Gadofosveset sodium, galiximab, ghrelin (human), glufosfamide; Homoharringtonine; Idraparinux sodium, imatinib mesylate, INS-37217; KRN-7000; L-651582, lafutidine, lanthanum carbonate, lenercept, levetiracetam, lusupultide; Magnesium sulfate, melatonin, mepolizumab, midostaurin, morphine hydrochloride, mozavaptan; Natalizumab, nesiritide; OPC-51803, oregovomab, oritavancin; Peginterferon alfa-2(a), pleconaril, plevitrexed, prasterone, pregabalin; Ranibizumab, Ro-31-7453, roxifiban acetate, rubitecan; SCV-07, SHL-749, sho-saiko-to, soblidotin, solifenacin succinate; Tegaserod maleate, telithromycin, tenecteplase, theraCIM, tipifarnib, travoprost; Valdecoxib, vardenafil hydrochloride hydrate, voriconazole; Ximelagatran; Ziprasidone hydrochloride, ZYC-00101. (c) 2003 Prous Science. All rights reserved.

Gateways to clinical trials.

PubMed

Bayes, M; Rabasseda, X; Prous, J R

2002-05-01

Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables can be retrieved from the Clinical Studies knowledge area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: Abacavir sulfate, abarelix, abciximab, acarbose, alefacept, alteplase, amisulpride, amoxicillin trihydrate, apomorphine hydrochloride, aprepitant, argatroban monohydrate, aspirin, atenolol; Betamethasone dipropionate, betamethasone valerate, bicalutamide, bleomycin sulfate; Calcium carbonate, candesartan cilexetil, celecoxib, cetirizine hydrochloride, cisplatin, clarithromycin, clavulanate potassium, clomethiazole edisilate, clopidogrel hydrogensulfate, cyclophosphamide, chorionic gonadotropin (human); Dalteparin sodium, desloratadine, dexamethasone, doxorubicin, DPC-083; Efalizumab, efavirenz, enoxaparin sodium, eprosartan mesilate, etanercept, etoposide, ezetimibe; Faropenem daloxate, fenofibrate, fluocinolone acetonide, flutamide, fluvastatin sodium, follitropin beta, fondaparinux sodium; Gabapentin, glibenclamide, goserelin, granisetron hydrochloride; Haloperidol, hydrochlorothiazide; Imiquimod, interferon beta-1a, irbesartan, iseganan hydrochloride; L-758298, lamivudine, lanoteplase, leflunomide, leuprorelin acetate, loratadine, losartan potassium; Melagatran, metformin hydrochloride, methotrexate, metronidazole, micafungin sodium, mitoxantrone hydrochloride; Nelfinavir mesilate, neutral insulin injection, nizatidine; Olopatadine hydrochloride, omeprazole, ondansetron hydrochloride; Pamidronate sodium, paracetamol, paroxetine hydrochloride, perindopril, pimecrolimus, pioglitazone hydrochloride, piroxicam, pleconaril, pralmorelin, pravastatin sodium, prednisolone, prednisone, propofol; Raloxifene hydrochloride, ranpirnase, remifentanil hydrochloride, risedronate sodium, risperidone, rofecoxib, ropinirole

Gateway National Recreational Area - Sandy Hook Unit : automated fee entrance plaza and intelligent transportation system technical requirements

DOT National Transportation Integrated Search

2009-01-01

The Volpe National Transportation Systems Center (Volpe Center) is providing technical : support to Sandy Hook, a unit of the Gateway National Recreation Area, in the planning and : concept development for possible Intelligent Transportation Systems ...

Radiometric Calibration of Earth Science Imagers Using HyCalCam on the Deep Space Gateway Platform

NASA Astrophysics Data System (ADS)

Butler, J. J.; Thome, K. J.

2018-02-01

HyCalCam, an SI-traceable imaging spectrometer on the Deep Space Gateway, acquires images of the Moon and Earth to characterize the lunar surface and terrestrial scenes for use as absolute calibration targets for on-orbit LEO and GEO sensors.

Evaluation of R1-6 gateway treatment alternatives for pedestrian crossings : follow-up report : final report.

DOT National Transportation Integrated Search

2017-06-01

Monthly follow-up data confirmed that permanent in roadway installations of the R1-6 gateway treatment led to an : increase in the percentage of drivers yielding to pedestrians at midblock and multilane urban and suburban locations : from 15% to 70% ...

The NC3Rs gateway: Accelerating scientific discoveries with new 3Rs models and technologies.

PubMed

Percie du Sert, Nathalie; Robinson, Vicky

2018-01-01

This editorial introduces the NC3Rs gateway, which publishes articles and reviews on new models and technologies emerging from NC3Rs-funded research. The aim is to raise awareness about these approaches, increase confidence in their capability, and provide sufficient information to facilitate their uptake by others.

Evaluation of R1-6 gateway treatment alternatives for pedestrian crossings : follow-up report : draft report.

DOT National Transportation Integrated Search

2016-12-01

Monthly follow-up data confirmed that permanent in roadway installations of the R1-6 gateway treatment led to an increase in the percentage of drivers yielding to pedestrians at midblock and multilane urban and suburban locations from 15% to 70% and ...

The Gateway Paper--financing health in Pakistan and its linkage with health reforms.

PubMed

Nishtar, Sania

2006-12-01

Pakistan currently principally uses three modes of financing health--taxation, out of pocket payments and donor contributions of which the latter is the least significant in terms of size. Less than 3.6% of the employees are covered under the social security scheme and there is a limited social protection mechanism, which collectively serves the health needs of 3.4% of the population. The main issues in health financing include low spending, lack of attention to alternate sources of financing and issues with fund mobilization and utilization. With respect to the first, health reforms proposed as part of the Gateway Paper make a strong case for promoting the reallocation of tax-based revenues and developing sustainable alternatives to low levels of public spending on health. With respect to alternative sources of health financing, the Gateway Paper lays stress on exploring policy options for private health insurance, broadening the base of Employees Social Security, creating a Federal Employees Social Security Programme, developing social health insurance within the framework of a broad-based social protection strategy, which scopes beyond the formally employed sector, establishing a widely inclusive safety net for the poor; mainstreaming philanthropic grants as a major source of health financing; developing a conducive tax configuration; generating greater corporate support for social sector causes within the framework of the concept of Corporate Social Responsibility and developing cost-sharing programmes, albeit with safeguards. The Gateway Paper regards efficient fund utilization a priority and lays stress on striking a balance between minimizing costs, controlling costs and using resources more efficiently and equitably--in other words, getting the best value for the money, on the one hand, and increasing the pool of available resources, on the other. Specific interventions such as the promotion of transparent financial administration, budgeting and cost

MIRATE: MIps RATional dEsign Science Gateway.

PubMed

Busato, Mirko; Distefano, Rosario; Bates, Ferdia; Karim, Kal; Bossi, Alessandra Maria; López Vilariño, José Manuel; Piletsky, Sergey; Bombieri, Nicola; Giorgetti, Alejandro

2018-06-13

Molecularly imprinted polymers (MIPs) are high affinity robust synthetic receptors, which can be optimally synthesized and manufactured more economically than their biological equivalents (i.e. antibody). In MIPs production, rational design based on molecular modeling is a commonly employed technique. This mostly aids in (i) virtual screening of functional monomers (FMs), (ii) optimization of monomer-template ratio, and (iii) selectivity analysis. We present MIRATE, an integrated science gateway for the intelligent design of MIPs. By combining and adapting multiple state-of-the-art bioinformatics tools into automated and innovative pipelines, MIRATE guides the user through the entire process of MIPs' design. The platform allows the user to fully customize each stage involved in the MIPs' design, with the main goal to support the synthesis in the wet-laboratory. MIRATE is freely accessible with no login requirement at http://mirate.di.univr.it/. All major browsers are supported.

Science Goals and Objectives for Canadian Robotic Exploration of the Moon Enabled by the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Bourassa, M.; Osinski, G. R.; Cross, M.; Hill, P.; King, D.; Morse, Z.; Pilles, E.; Tolometti, G.; Tornabene, L. L.; Zanetti, M.

2018-02-01

Canadian contributions to the science goals and objectives of a lunar precursor rover for HERACLES, an international mission concept, are discussed. Enabled by the Deep Space Gateway, this rover is a technical demonstrator for robotic sample return.

The New Gateway, an Old Paradox: Immigrants and Involuntary Americans in North Carolina History Textbooks

ERIC Educational Resources Information Center

Hilburn, Jeremy; Fitchett, Paul G.

2012-01-01

The authors conducted a content analysis of North Carolina history textbooks to explore how the definition of immigration has changed over the last century. They also examined how immigrant groups and involuntary Americans have been portrayed throughout the state's history. Findings suggest that as a burgeoning gateway state for immigrants, North…

Using Collaborative Two-Stage Examinations to Address Test Anxiety in a Large Enrollment Gateway Course

ERIC Educational Resources Information Center

Fournier, Kimberly A.; Couret, Jannelle; Ramsay, Jason B.; Caulkins, Joshua L.

2017-01-01

Large enrollment foundational courses are perceived as "high stakes" because of their potential to act as barriers for progression to the next course or admittance to a program. The nature of gateway courses makes them ideal settings to explore the relationship between anxiety, pedagogical interventions, and student performance. Here,…

The NC3Rs gateway: Accelerating scientific discoveries with new 3Rs models and technologies

PubMed Central

Percie du Sert, Nathalie; Robinson, Vicky

2018-01-01

This editorial introduces the NC3Rs gateway, which publishes articles and reviews on new models and technologies emerging from NC3Rs-funded research. The aim is to raise awareness about these approaches, increase confidence in their capability, and provide sufficient information to facilitate their uptake by others. PMID:29862024

Recombinational Cloning Using Gateway and In-Fusion Cloning Schemes

PubMed Central

Throop, Andrea L.; LaBaer, Joshua

2015-01-01

The comprehensive study of protein structure and function, or proteomics, depends on the obtainability of full-length cDNAs in species-specific expression vectors and subsequent functional analysis of the expressed protein. Recombinational cloning is a universal cloning technique based on site-specific recombination that is independent of the insert DNA sequence of interest, which differentiates this method from the classical restriction enzyme-based cloning methods. Recombinational cloning enables rapid and efficient parallel transfer of DNA inserts into multiple expression systems. This unit summarizes strategies for generating expression-ready clones using the most popular recombinational cloning technologies, including the commercially available Gateway® (Life Technologies) and In-Fusion® (Clontech) cloning technologies. PMID:25827088

Long-Range Plan for Gateway Technical Institute. 1982-1987: Serving Kenosha, Racine, and Walworth Counties.

ERIC Educational Resources Information Center

Stoehr, Keith W.; Covelli, Nicholas J.

This report presents Gateway Technical Institute's long-range plan for 1982-1987. After prefatory material discussing financial and non-financial factors that may impinge on the plan, Chapter I outlines the socioeconomic situation in the three-county area of Wisconsin served by the college and introduces some of the critical issues that the…

Gateways to clinical trials.

PubMed

Bayes, M; Rabasseda, X; Prous, J R

2003-05-01

Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Studies knowledge area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: 2F5, 2G12, abetimus sodium, ABI-007, adalimumab, adefovir dipivoxil, AE-941, alefacept, altropane, aminolevulinic acid hydrochloride, aminolevulinic acid methyl ester, aminopterin, anakinra, aprinocarsen sodium, atazanavir, atlizumab, atomoxetine hydrochloride; B7-1 vaccine, bevacizumab, biricodar dicitrate, BMS-188667, brasofensine sulfate, bryostatin 1; cantuzumab mertansine, CHS-828, cinacalcet hydrochloride, cipamfylline, creatine, CVT-3146; darbepoetin alfa, DITPA, drotrecogin alfa (activated), duloxetine hydrochloride; edatrexate, efalizumab, ENMD-0997, epoetin, erlosamide, esomeprazole magnesium, etiprednol dicloacetate, etoricoxib, everolimus, ezetimibe; fampridine, fenretinide, FTY-720; IGF-I/IGFBP-3, IL-1 cytokine trap, ilodecakin, interferon beta, ISIS-104838, ISIS-2503, ISIS-5132, ivabradine hydrochloride; lafutidine, lanthanum carbonate, l-Arginine hydrochloride, LEA29Y, lerdelimumab, levetiracetam, levobupivacaine hydrochloride, levosimendan, lopinavir; melagatran, mibefradil hydrochloride, miglustat, morphine-6-glucuronide; nesiritide; omalizumab, omapatrilat; p24-VLP, parecoxib sodium, peginterferon alfa-2a, peginterferon alfa-2b, pegsunercept, pitavastatin calcium, plevitrexed, prasterone, pregabalin, PRO-2000, prucalopride; rapacuronium bromide, rebimastat, RGA-0853, rubitecan, ruboxistaurin mesilate hydrate, RWJ-67657; S-16020-2, sarizotan, SLV-306, stiripentol; TA-CIN, tenecteplase, teriparatide, tezacitabine, tipifarnib, trabectedin, troglitazone; valdecoxib, vardenafil; Z-338, ziconotide.

Gateways to clinical trials.

PubMed

Bayés, M; Rabasseda, X; Prous, J R

2005-12-01

Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity. prous.com. This issue focuses on the following selection of drugs: 131I-chTNT; Abatacept, adalimumab, alemtuzumab, APC-8015, aprepitant, atazanavir sulfate, atomoxetine hydrochloride, azimilide hydrochloride; Bevacizumab, bortezomib, bosentan, buserelin; Caspofungin acetate, CC-4047, ChAGCD3, ciclesonide, clopidogrel, curcumin, Cypher; Dabigatran etexilate, dapoxetine hydrochloride, darbepoetin alfa, darusentan, denosumab, DMXB-Anabaseine, drospirenone, drospirenone/estradiol, duloxetine hydrochloride, dutasteride; Edodekin alfa, efaproxiral sodium, elaidic acid-cytarabine, erlotinib hydrochloride, ertapenem sodium, escitalopram oxalate, eszopiclone, etonogestrel/testosterone decanoate, exenatide; Fulvestrant; Gefitinib, glycine, GVS-111; Homoharringtonine; ICC-1132, imatinib mesylate, iodine (I131) tositumomab, i.v. gamma-globulin; Levetiracetam, levocetirizine, lintuzumab, liposomal nystatin, lumiracoxib, lurtotecan; Manitimus, mapatumumab, melatonin, micafungin sodium, mycophenolic acid sodium salt; Oblimersen sodium, OGX-011, olmesartan medoxomil, omalizumab, omapatrilat, oral insulin; Parathyroid hormone (human recombinant), pasireotide, peginterferon alfa-2a, peginterferon alfa-2b, peginterferon alfa-2b/ribavirin, phVEGF-A165, pimecrolimus, pitavastatin calcium, plerixafor hydrochloride, posaconazole, pramlintide acetate, prasterone, pregabalin, PT-141; Quercetin; Ranolazine, rosuvastatin calcium, rubitecan, rupatadine fumarate; Sardomozide, sunitinib malate; Tadalafil, talactoferrin alfa, tegaserod maleate, telithromycin, testosterone transdermal patch, TH-9507, tigecycline, tiotropium bromide, tipifarnib, tocilizumab, treprostinil sodium; Valdecoxib, vandetanib

Gateways to Clinical Trials.

PubMed

Bayés, M; Rabasseda, X; Prous, J R

2002-09-01

Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Studies knowledge area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: Adalimumab, aeroDose insulin inhaler, agomelatine, alendronic acid sodium salt, aliskiren fumarate, alteplase, amlodipine, aspirin, atazanavir; Bacillus Calmette-Guérin, basiliximab, BQ-788, bupropion hydrochloride; Cabergoline, caffeine citrate, carbamazepine, carvedilol, celecoxib, cyclosporine, clopidogrel hydrogensulfate, colestyramine; Dexamethasone, diclofenac sodium, digoxin, dipyridamole, docetaxel, dutasteride; Eletriptan, enfuvirtidie, eplerenone, ergotamine tartrate, esomeprazole magnesium, estramustine phosphate sodium; Finasteride, fluticasone propionate, fosinopril sodium; Ganciclovir, GBE-761-ONC, glatiramer acetate, gliclazide, granulocyte-CSF; Heparin sodium, human isophane insulin (pyr), Hydrochlorothiazide; Ibuprofen, inhaled insulin, interferon alfa, interferon beta-1a; Laminvudine, lansoprazole, lisinopril, lonafarnib, losartan potassium, lumiracoxib; MAb G250, meloxicam methotrexate, methylprednisolone aceponate, mitomycin, mycophenolate mofetil; Naproxen sodium, natalizumab, nelfinavir mesilate, nemifitide ditriflutate, nimesulide; Omalizumab, omapatrilat, omeprazole, oxybutynin chloride; Pantoprazole sodium, paracetamol, paroxetine, pentoxifylline, pergolide mesylate, permixon, phVEGF-A165, pramipexole hydrochloride, prasterone, prednisone, probucol, propiverine hydrochloride; Rabeprazole sodium, resiniferatoxin, risedronate sodium, risperidone, rofecoxib rosiglitazone maleate, ruboxistaurin mesilate hydrate; Selegiline transdermal system, sertraline, sildenafil citrate, streptokinase; Tadalafil, tamsulosin hydrochloride, technosphere/Insulin, tegaserod maleate, tenofovir disoproxil

Chronic Nicotine Exposure Initiated in Adolescence and Unpaired to Behavioral Context Fails to Enhance Sweetened Ethanol Seeking

PubMed Central

Madayag, Aric C.; Czarnecki, Kyle S.; Wangler, Lynde M.; Robinson, Donita L.

2017-01-01

Nicotine use in adolescence is pervasive in the United States and, according to the Gateway Hypothesis, may lead to progression towards other addictive substances. Given the prevalence of nicotine and ethanol comorbidity, it is difficult to ascertain if nicotine is a gateway drug for ethanol. Our study investigated the relationship between adolescent exposure to nicotine and whether this exposure alters subsequent alcohol seeking behavior. We hypothesized that rats exposed to nicotine beginning in adolescence would exhibit greater alcohol seeking behavior than non-exposed siblings. To test our hypothesis, beginning at P28, female rats were initially exposed to once daily nicotine (0.4 mg/kg, SC) or saline for 5 days. Following these five initial injections, animals were trained to nose-poke for sucrose reinforcement (10%, w/v), gradually increasing to sweetened ethanol (10% sucrose; 10% ethanol, w/v) on an FR5 reinforcement schedule. Nicotine injections were administered after the behavioral sessions to minimize acute effects of nicotine on operant self-administration. We measured the effects of nicotine exposure on the following aspects of ethanol seeking: self-administration, naltrexone (NTX)-induced decreases, habit-directed behavior, motivation, extinction and reinstatement. Nicotine exposure did not alter self-administration or the effectiveness of NTX to reduce alcohol seeking. Nicotine exposure blocked habit-directed ethanol seeking. Finally, nicotine did not alter extinction learning or cue-induced reinstatement to sweetened ethanol seeking. Our findings suggest that nicotine exposure outside the behavioral context does not escalate ethanol seeking. Further, the Gateway Hypothesis likely applies to scenarios in which nicotine is either self-administered or physiologically active during the behavioral session. PMID:28860980

Earth Observing System Data Gateway

NASA Technical Reports Server (NTRS)

Pfister, Robin; McMahon, Joe; Amrhein, James; Sefert, Ed; Marsans, Lorena; Solomon, Mark; Nestler, Mark

2006-01-01

The Earth Observing System Data Gateway (EDG) software provides a "one-stop-shopping" standard interface for exploring and ordering Earth-science data stored at geographically distributed sites. EDG enables a user to do the following: 1) Search for data according to high-level criteria (e.g., geographic location, time, or satellite that acquired the data); 2) Browse the results of a search, viewing thumbnail sketches of data that satisfy the user s criteria; and 3) Order selected data for delivery to a specified address on a chosen medium (e.g., compact disk or magnetic tape). EDG consists of (1) a component that implements a high-level client/server protocol, and (2) a collection of C-language libraries that implement the passing of protocol messages between an EDG client and one or more EDG servers. EDG servers are located at sites usually called "Distributed Active Archive Centers" (DAACs). Each DAAC may allow access to many individual data items, called "granules" (e.g., single Landsat images). Related granules are grouped into collections called "data sets." EDG enables a user to send a search query to multiple DAACs simultaneously, inspect the resulting information, select browseable granules, and then order selected data from the different sites in a seamless fashion.

Space Biology Model Organism Research on the Deep Space Gateway to Pioneer Discovery and Advance Human Space Exploration

NASA Astrophysics Data System (ADS)

Sato, K. Y.; Tomko, D. L.; Levine, H. G.; Quincy, C. D.; Rayl, N. A.; Sowa, M. B.; Taylor, E. M.; Sun, S. C.; Kundrot, C. E.

2018-02-01

Model organisms are foundational for conducting physiological and systems biology research to define how life responds to the deep space environment. The organisms, areas of research, and Deep Space Gateway capabilities needed will be presented.

The Divine Dreams of a Sample of South African Children: The Gateway to Their Spirituality

ERIC Educational Resources Information Center

Potgieter, Ferdinand J.; van der Walt, Johannes L.; Wolhuter, Charl C.

2009-01-01

As part of a research project on religion, spirituality and education, the authors attended to the role that children's divine dreams could play in religious education (RE). They contend that such dreams can indeed be used by RE teachers as the gateway to understanding the spirituality of their learners. They defend their claim by firstly…

78 FR 79707 - Notice of Public Meeting, Gateway West Project Subcommittee of the Boise District Resource...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-31

... Resource Advisory Council on matters of planning and management of the Gateway West Project (sections 8 and... Interior, through the BLM, on a variety of planning and management issues associated with public land... a telecommunications device for the deaf (TDD) may call the Federal Information Relay Service (FIRS...

Gateways to the Internet: A Host of Companies Want To Be Your District's Customized Education Portal.

ERIC Educational Resources Information Center

Bushweller, Kevin

2000-01-01

In the ephemeral dot.com economy, numerous education portals (search engines) are emerging just as unsuccessful ones are terminating or trimming services. Ideally, portals offer an online school/home gateway and provide tailored content for parents, students, and teachers. However, quality, equity, reliability, and commercialism issues abound.…

Disaster Response Tools for Decision Support and Data Discovery - E-DECIDER and GeoGateway

NASA Astrophysics Data System (ADS)

Glasscoe, M. T.; Donnellan, A.; Parker, J. W.; Granat, R. A.; Lyzenga, G. A.; Pierce, M. E.; Wang, J.; Grant Ludwig, L.; Eguchi, R. T.; Huyck, C. K.; Hu, Z.; Chen, Z.; Yoder, M. R.; Rundle, J. B.; Rosinski, A.

2015-12-01

Providing actionable data for situational awareness following an earthquake or other disaster is critical to decision makers in order to improve their ability to anticipate requirements and provide appropriate resources for response. E-DECIDER (Emergency Data Enhanced Cyber-Infrastructure for Disaster Evaluation and Response) is a decision support system producing remote sensing and geophysical modeling products that are relevant to the emergency preparedness and response communities and serves as a gateway to enable the delivery of actionable information to these communities. GeoGateway is a data product search and analysis gateway for scientific discovery, field use, and disaster response focused on NASA UAVSAR and GPS data that integrates with fault data, seismicity and models. Key information on the nature, magnitude and scope of damage, or Essential Elements of Information (EEI), necessary to achieve situational awareness are often generated from a wide array of organizations and disciplines, using any number of geospatial and non-geospatial technologies. We have worked in partnership with the California Earthquake Clearinghouse to develop actionable data products for use in their response efforts, particularly in regularly scheduled, statewide exercises like the recent May 2015 Capstone/SoCal NLE/Ardent Sentry Exercises and in the August 2014 South Napa earthquake activation. We also provided a number of products, services, and consultation to the NASA agency-wide response to the April 2015 Gorkha, Nepal earthquake. We will present perspectives on developing tools for decision support and data discovery in partnership with the Clearinghouse and for the Nepal earthquake. Products delivered included map layers as part of the common operational data plan for the Clearinghouse, delivered through XchangeCore Web Service Data Orchestration, enabling users to create merged datasets from multiple providers. For the Nepal response effort, products included models

GATEWAY Report Brief: Evaluating OLED Lighting in the Accounting Office of DeJoy, Knauf & Blood LLP

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Summary of GATEWAY report evaluating a new lighting system, at the offices of the accounting firm of DeJoy, Knauf & Blood, LLP in Rochester, NY, that incorporates a number of different OLED luminaires. Evaluation of the OLED products included efficacy performance, field measurements of panel color, flicker measurements, and staff feedback.

A Gateway to Health Careers for Urban High School Students: Collaborative Front-Line and Allied Workforce Development Program among High Schools, Public Hospitals and Public Colleges. Program Results Report

ERIC Educational Resources Information Center

Jablow, Paul

2012-01-01

From 2005 to 2011, the Gateway Institute for Pre-College Education partnered with three public entities in New York City--the Department of Education, the City University of New York and the Health and Hospitals Corporation--to introduce, educate, and prepare urban high school students for careers in the health professions. Gateway was launched in…

Amplified North Atlantic Warming in the Late Pliocene by Changes in Arctic Gateways

NASA Astrophysics Data System (ADS)

Otto-Bliesner, B. L.; Jahn, A.; Feng, R.; Brady, E. C.; Hu, A.; Lofverstrom, M.

2017-12-01

Reconstructions of the late Pliocene (mid-Piacenzian, 3.3 - 3.0 million years ago) sea surface temperature (SST) find much warmer conditions in the North Atlantic than modern. The much warmer SSTs, up to 8.8°C from sites with good dating and replicates from several different types of proxies, have been difficult for climate models to reproduce. Even with the slow feedbacks of a reduced Greenland ice sheet and expansion of boreal forests to the Arctic Ocean over Canada and Eurasia, models cannot warm the North Atlantic sufficiently to match the reconstructed SSTs. An enhancement of the Atlantic Meridional Overturning Circulation (AMOC) during the late Pliocene, proposed as a possible mechanism based on ocean core records of δ13C, also is not present in the model simulations. Here, we present CESM simulations using a new reconstruction of late Pliocene paleogeography that has the Bering Strait (BS) and Canadian Arctic Archipelago (CAA) Straits closed. We find that the closure of these small Arctic gateways strengthens the AMOC, by inhibiting freshwater (FW) transport from the Pacific to the Arctic Ocean and from the Arctic Ocean to the Labrador Sea, leading to warmer sea surface temperatures in the North Atlantic. The cutoff of the short export route through the CAA results in a more saline Labrador and south Greenland Sea with increased deep convection. At the same time, as all FW now leaves the Arctic east of Greenland, there is a freshening of and decreased deepwater formation in the Norwegian Sea. Overall, the AMOC strengthens. This past time period has implications for a future Earth under more responsible scenarios of emissions. Late Pliocene atmospheric carbon dioxide concentrations are estimated to have ranged between 350 and 450 ppmv and the paleogeography is relatively similar to modern. Our study indicates that the state of the Arctic gateways may influence the sensitivity of the North Atlantic climate in complex ways, and better understanding of the

Gateways to clinical trials.

PubMed

Bayés, M; Rabasseda, X; Prous, J R

2007-12-01

Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Trials Knowledge Area of Prous Science Intergrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: 249553, 2-Methoxyestradiol; Abatacept, Adalimumab, Adefovir dipivoxil, Agalsidase beta, Albinterferon alfa-2b, Aliskiren fumarate, Alovudine, Amdoxovir, Amlodipine besylate/atorvastatin calcium, Amrubicin hydrochloride, Anakinra, AQ-13, Aripiprazole, AS-1404, Asoprisnil, Atacicept, Atrasentan; Belimumab, Bevacizumab, Bortezomib, Bosentan, Botulinum toxin type B, Brivaracetam; Catumaxomab, Cediranib, Cetuximab, cG250, Ciclesonide, Cinacalcet hydrochloride, Curcumin, Cypher; Darbepoetin alfa, Denosumab, Dihydrexidine; Eicosapentaenoic acid/docosahexaenoic acid, Entecavir, Erlotinib hydrochloride, Escitalopram oxalate, Etoricoxib, Everolimus, Ezetimibe; Febuxostat, Fenspiride hydrochloride, Fondaparinux sodium; Gefitinib, Ghrelin (human), GSK-1562902A; HSV-tk/GCV; Iclaprim, Imatinib mesylate, Imexon, Indacaterol, Insulinotropin, ISIS-112989; L-Alanosine, Lapatinib ditosylate, Laropiprant; Methoxy polyethylene glycol-epoetin-beta, Mipomersen sodium, Motexafin gadolinium; Natalizumab, Nimotuzumab; OSC, Ozarelix; PACAP-38, Paclitaxel nanoparticles, Parathyroid Hormone-Related Protein-(1-36), Pasireotide, Pegfilgrastim, Peginterferon alfa-2a, Peginterferon alfa-2b, Pemetrexed disodium, Pertuzumab, Picoplatin, Pimecrolimus, Pitavastatin calcium, Plitidepsin; Ranelic acid distrontium salt, Ranolazine, Recombinant human relaxin H2, Regadenoson, RFB4(dsFv)-PE38, RO-3300074, Rosuvastatin calcium; SIR-Spheres, Solifenacin succinate, Sorafenib, Sunitinib malate; Tadalafil, Talabostat, Taribavirin hydrochloride, Taxus, Temsirolimus, Teriparatide, Tiotropium bromide, Tipifarnib, Tirapazamine, Tocilizumab; UCN-01, Ularitide

EAARL topography: Gateway National Recreation Area

USGS Publications Warehouse

Brock, John C.; Wright, C. Wayne; Patterson, Matt; Nayegandhi, Amar; Patterson, Judd

2007-01-01

This Web site contains Lidar-derived topography (bare earth) maps and GIS files for the Sandy Hook Unit within Gateway National Recreation Area in New Jersey. These Lidar-derived topography maps were produced as a collaborative effort between the U.S. Geological Survey (USGS) Coastal and Marine Geology Program, FISC St. Petersburg, the National Park Service (NPS) South Florida/Caribbean Network Inventory and Monitoring Program, and the National Aeronautics and Space Administration (NASA) Wallops Flight Facility. One objective of this research is to create techniques to survey coral reefs and barrier islands for the purposes of geomorphic change studies, habitat mapping, ecological monitoring, change detection, and event assessment. As part of this project, data from an innovative instrument under development at the NASA Wallops Flight Facility, the NASA Experimental Airborne Advanced Research Lidar (EAARL) are being used. This sensor has the potential to make significant contributions in this realm for measuring subaerial and submarine topography wthin cross-environment surveys. High spectral resolution, water-column correction, and low costs were found to be key factors in providing accurate and affordable imagery to costal resource managers.

Amplified Late Pliocene terrestrial warmth in northern high latitudes from greater radiative forcing and closed Arctic Ocean gateways

NASA Astrophysics Data System (ADS)

Feng, Ran; Otto-Bliesner, Bette L.; Fletcher, Tamara L.; Tabor, Clay R.; Ballantyne, Ashley P.; Brady, Esther C.

2017-05-01

Proxy reconstructions of the mid-Piacenzian warm period (mPWP, between 3.264 and 3.025 Ma) suggest terrestrial temperatures were much warmer in the northern high latitudes (55°-90°N, referred to as NHL) than present-day. Climate models participating in the Pliocene Model Intercomparison Project Phase 1 (PlioMIP1) tend to underestimate this warmth. For instance, the underestimate is ∼10 °C on average across NHL and up to 17 °C in the Canadian Arctic region in the Community Climate System Model version 4 (CCSM4). Here, we explore potential mPWP climate forcings that might contribute to this mPWP mismatch. We carry out seven experiments to assess terrestrial temperature responses to Pliocene Arctic gateway closure, variations in CO2 level, and orbital forcing at millennial time scale. To better compare the full range of simulated terrestrial temperatures with sparse proxy data, we introduce a pattern recognition technique that simplifies the model surface temperatures to a few representative patterns that can be validate with the limited terrestrial proxy data. The pattern recognition technique reveals two prominent features of simulated Pliocene surface temperature responses. First, distinctive patterns of amplified warming occur in the NHL, which can be explained by lowered surface elevation of Greenland, pattern and amount of Arctic sea ice loss, and changing strength of Atlantic meridional overturning circulation. Second, patterns of surface temperature response are similar among experiments with different forcing mechanisms. This similarity is due to strong feedbacks from responses in surface albedo and troposphere water vapor content to sea ice changes, which overwhelm distinctions in forcings from changes in insolation, CO2 forcing, and Arctic gateway closure. By comparing CCSM4 simulations with proxy records, we demonstrate that both model and proxy records show similar patterns of mPWP NHL terrestrial warmth, but the model underestimates the magnitude

On the capability of smartphones to perform as communication gateways in medical wireless personal area networks.

PubMed

Morón, María José; Luque, Rafael; Casilari, Eduardo

2014-01-02

This paper evaluates and characterizes the technical performance of medical wireless personal area networks (WPANs) that are based on smartphones. For this purpose,a prototype of a health telemonitoring system is presented. The prototype incorporates a commercial Android smartphone, which acts as a relay point, or "gateway", between a set of wireless medical sensors and a data server. Additionally, the paper investigates if the conventional capabilities of current commercial smartphones can be affected by their use as gateways or "Holters" in health monitoring applications. Specifically, the profiling has focused on the CPU and power consumption of the mobile devices. These metrics have been measured under several test conditions modifying the smartphone model, the type of sensors connected to the WPAN, the employed Bluetooth profile (SPP (serial port profile) orHDP (health device profile)), the use of other peripherals, such as a GPS receiver, the impact of the use of the Wi-Fi interface or the employed method to encode and forward the data that are collected from the sensors.

Remote In-Space Manufacturing Applied with the Science of Interplanetary Supply Chain Modeling for Deep Space Gateway Application

NASA Astrophysics Data System (ADS)

Galluzzi, M. C.

2018-02-01

Three goals can be achieved by 2030: 1. NASA will have the capability for remote on-demand 3d printing of critical hardware using regolith material as feedstock, 2. Logistics footprint reduced by 35%, 3. Deep Space Gateway will become 75% self-sustaining.

78 FR 70959 - Gateway West Project Subcommittee of the Resource Advisory Council to the Boise District; Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-27

... advises the Boise District Resource Advisory Council on matters of planning and management of the Gateway... the Interior, through the BLM, on a variety of planning and management issues associated with public.... Persons who use a telecommunications device for the deaf (TDD) may call the Federal Information Relay...

The Common Gateway Interface (CGI) for Enhancing Access to Database Servers via the World Wide Web (WWW).

ERIC Educational Resources Information Center

Machovec, George S., Ed.

1995-01-01

Explains the Common Gateway Interface (CGI) protocol as a set of rules for passing information from a Web server to an external program such as a database search engine. Topics include advantages over traditional client/server solutions, limitations, sample library applications, and sources of information from the Internet. (LRW)

The airway antigen sampling system: respiratory M cells as an alternative gateway for inhaled antigens.

PubMed

Kim, Dong-Young; Sato, Ayuko; Fukuyama, Satoshi; Sagara, Hiroshi; Nagatake, Takahiro; Kong, Il Gyu; Goda, Kaoru; Nochi, Tomonori; Kunisawa, Jun; Sato, Shintaro; Yokota, Yoshifumi; Lee, Chul Hee; Kiyono, Hiroshi

2011-04-01

In this study, we demonstrated a new airway Ag sampling site by analyzing tissue sections of the murine nasal passages. We revealed the presence of respiratory M cells, which had the ability to take up OVA and recombinant Salmonella typhimurium expressing GFP, in the turbinates covered with single-layer epithelium. These M cells were also capable of taking up respiratory pathogen group A Streptococcus after nasal challenge. Inhibitor of DNA binding/differentiation 2 (Id2)-deficient mice, which are deficient in lymphoid tissues, including nasopharynx-associated lymphoid tissue, had a similar frequency of M cell clusters in their nasal epithelia to that of their littermates, Id2(+/-) mice. The titers of Ag-specific Abs were as high in Id2(-/-) mice as in Id2(+/-) mice after nasal immunization with recombinant Salmonella-ToxC or group A Streptococcus, indicating that respiratory M cells were capable of sampling inhaled bacterial Ag to initiate an Ag-specific immune response. Taken together, these findings suggest that respiratory M cells act as a nasopharynx-associated lymphoid tissue-independent alternative gateway for Ag sampling and subsequent induction of Ag-specific immune responses in the upper respiratory tract.

The Battle Command Sustainment Support System: Initial Analysis Report

DTIC Science & Technology

2016-09-01

diagnostic monitoring, asynchronous commits, and others. The other components of the NEDP include a main forwarding gateway /web server and one or more...NATIONAL ENTERPRISE DATA PORTAL ANALYSIS The NEDP is comprised of an Oracle Database 10g referred to as the National Data Server and several other...data forwarding gateways (DFG). Together, with the Oracle Database 10g, these components provide a heterogeneous data source that aligns various data

Van Allen Probes Science Gateway: Single-Point Access to Long-Term Radiation Belt Measurements and Space Weather Nowcasting

NASA Astrophysics Data System (ADS)

Romeo, G.; Barnes, R. J.; Ukhorskiy, A. Y.; Sotirelis, T.; Stephens, G.

2017-12-01

The Science Gateway gives single-point access to over 4.5 years of comprehensive wave and particle measurements from the Van Allen Probes NASA twin-spacecraft mission. The Gateway provides a set of visualization and data analysis tools including: HTML5-based interactive visualization of high-level data products from all instrument teams in the form of: line plots, orbital content plots, dynamical energy spectra, L-shell context plots (including two-spacecraft plotting), FFT spectra of wave data, solar wind and geomagnetic indices data, etc.; download custom multi-instrument CDF data files of selected data products; publication quality plots of digital data; combined orbit predicts for mission planning and coordination including: Van Allen Probes, MMS, THEMIS, Arase (ERG), Cluster, GOES, Geotail, FIREBIRD; magnetic footpoint calculator for coordination with LEO and ground-based assets; real-time computation and processing of empirical magnetic field models - computation of magnetic ephemeris, computation of adiabatic invariants. Van Allen Probes is the first spacecraft mission to provide a nowcast of the radiation environment in the heart of the radiation belts, where the radiation levels are the highest and most dangerous for spacecraft operations. For this purpose, all instruments continuously broadcast a subset of their science data in real time. Van Allen Probes partners with four foreign institutions who operate ground stations that receive the broadcast: Korea (KASI), the Czech republic (CAS), Argentina (CONAE), and Brazil (INPE). The SpWx broadcast is then collected at APL and delivered to the community via the Science Gateway.

Internet-to-orbit gateway and virtual ground station: A tool for space research and scientific outreach

NASA Astrophysics Data System (ADS)

Jaffer, Ghulam; Nader, Ronnie; Koudelka, Otto

2011-09-01

Students in higher education, and scientific and technological researchers want to communicate with the International Space Station (ISS), download live satellite images, and receive telemetry, housekeeping and science/engineering data from nano-satellites and larger spacecrafts. To meet this need the Ecuadorian Civilian Space Agency (EXA) has recently provided the civilian world with an internet-to-orbit gateway (Hermes-A/Minotaur) Space Flight Control Center (SFCC) available for public use. The gateway has a maximum range of tracking and detection of 22,000 km and sensitivity such that it can receive and discriminate the signals from a satellite transmitter with power˜0.1 W. The capability is enough to receive the faintest low-earth-orbit (LEO) satellites. This gateway virtually connects participating internet clients around the world to a remote satellite ground station (GS), providing a broad community for multinational cooperation. The goal of the GS is to lower financial and engineering barriers that hinder access to science and engineering data from orbit. The basic design of the virtual GS on a user side is based on free software suites. Using these and other software tools the GS is able to provide access to orbit for a multitude of users without each having to go through the costly setups. We present the design and implementation of the virtual GS in a higher education and scientific outreach settings. We also discuss the basic architecture of the single existing system and the benefits of a proposed distributed system. Details of the software tools and their applicability to synchronous round-the-world tracking, monitoring and processing performed by students and teams at Graz University of Technology, Austria, EXA-Ecuador, University of Michigan, USA and JAXA who have participated in various mission operations and have investigated real-time satellite data download and image acquisition and processing. Students and other remote users at these

Guiding Early and Often: Using Curricular and Learning Analytics to Shape Teaching, Learning, and Student Success in Gateway Courses

ERIC Educational Resources Information Center

Pistilli, Matthew D.; Heileman, Gregory L.

2017-01-01

This chapter provides information on how the promise of analytics can be realized in gateway courses through a combination of good data science and the thoughtful application of outcomes to teaching and learning improvement efforts--especially with and among instructors.

Functional Adult Literacy: An Alternative Gateway to Grassroots Women's Improved Income Generation in Lango Subregion, Northern Uganda

ERIC Educational Resources Information Center

Akello, Judith Abal; Lutwama-Rukundo, Evelyn; Musiimenta, Peace

2017-01-01

This article presents findings of study on women's experiences of Functional Adult Literacy (FAL) as a gateway to their financial progress and welfare in Lango region, Northern Uganda. The qualitative study of 45 participants aimed at examining women's live changes resulting from using their acquired FAL knowledge and skills to participate in…

Network gateway security method for enterprise Grid: a literature review

NASA Astrophysics Data System (ADS)

Sujarwo, A.; Tan, J.

2017-03-01

The computational Grid has brought big computational resources closer to scientists. It enables people to do a large computational job anytime and anywhere without any physical border anymore. However, the massive and spread of computer participants either as user or computational provider arise problems in security. The challenge is on how the security system, especially the one which filters data in the gateway could works in flexibility depends on the registered Grid participants. This paper surveys what people have done to approach this challenge, in order to find the better and new method for enterprise Grid. The findings of this paper is the dynamically controlled enterprise firewall to secure the Grid resources from unwanted connections with a new firewall controlling method and components.

Complex Cloud and Radiative Processes Unfolding at the Earth's Terminator: A Unique Perspective from the Proposed Deep Space Gateway

NASA Astrophysics Data System (ADS)

Davis, A. B.; Marshak, A.

2018-02-01

The Deep Space Gateway offers a unique vantage for Earth observation using reflected sunlight: day/night or night/day terminators slowly marching across the disc. It's an opportunity to improve our understanding of clouds at that key moment in their daily cycle.

Deep Space Gateway Facilitates Exploration of Planetary Crusts: A Human/Robotic Exploration Design Reference Campaign to the Lunar Orientale Basin

NASA Astrophysics Data System (ADS)

Head, J. W.; Pieters, C. M.; Scott, D. R.

2018-02-01

We outline an Orientale Basin Human/Robotic Architecture that can be facilitated by a Deep Space Gateway International Science Operations Center (DSG-ISOC) (like McMurdo/Antarctica) to address fundamental scientific problems about the Moon and Mars.

The Medical Imaging Interaction Toolkit: challenges and advances : 10 years of open-source development.

PubMed

Nolden, Marco; Zelzer, Sascha; Seitel, Alexander; Wald, Diana; Müller, Michael; Franz, Alfred M; Maleike, Daniel; Fangerau, Markus; Baumhauer, Matthias; Maier-Hein, Lena; Maier-Hein, Klaus H; Meinzer, Hans-Peter; Wolf, Ivo

2013-07-01

The Medical Imaging Interaction Toolkit (MITK) has been available as open-source software for almost 10 years now. In this period the requirements of software systems in the medical image processing domain have become increasingly complex. The aim of this paper is to show how MITK evolved into a software system that is able to cover all steps of a clinical workflow including data retrieval, image analysis, diagnosis, treatment planning, intervention support, and treatment control. MITK provides modularization and extensibility on different levels. In addition to the original toolkit, a module system, micro services for small, system-wide features, a service-oriented architecture based on the Open Services Gateway initiative (OSGi) standard, and an extensible and configurable application framework allow MITK to be used, extended and deployed as needed. A refined software process was implemented to deliver high-quality software, ease the fulfillment of regulatory requirements, and enable teamwork in mixed-competence teams. MITK has been applied by a worldwide community and integrated into a variety of solutions, either at the toolkit level or as an application framework with custom extensions. The MITK Workbench has been released as a highly extensible and customizable end-user application. Optional support for tool tracking, image-guided therapy, diffusion imaging as well as various external packages (e.g. CTK, DCMTK, OpenCV, SOFA, Python) is available. MITK has also been used in several FDA/CE-certified applications, which demonstrates the high-quality software and rigorous development process. MITK provides a versatile platform with a high degree of modularization and interoperability and is well suited to meet the challenging tasks of today's and tomorrow's clinically motivated research.

Gateway to Healthcare Careers for Vulnerable Students: A New Approach to the Teaching of Anatomy and Physiology

ERIC Educational Resources Information Center

DeCiccio, Albert; Kenny, Tammy; Lippacher, Linda; Flanary, Barry

2011-01-01

At Southern Vermont College (SVC) and at the nation's other colleges and universities, Anatomy and Physiology I (A&PI) is the gateway course into healthcare careers. Disturbingly, at SVC and elsewhere, many first-year students interested in healthcare careers do not succeed in this course. They withdraw from the course or the institution, or…

Resources in the VLab Science Gateway: Online applications for thermodynamics and thermal elastic properties of mantle minerals

NASA Astrophysics Data System (ADS)

Wentzcovitch, R. M.; Da Silveira, P. R.; Wu, Z.; Yu, Y.

2013-12-01

Today first principles calculations in mineral physics play a fundamental role in understanding of the Earth. They complement experiments by expanding the pressure and temperature range for which properties can be obtained and provide access to atomic scale phenomena. Since the wealth of predictive first principles results can hardly be communicated in printed form, we have developed online applications where published results can be reproduced/verified online and extensive unpublished results can be generated in customized form. So far these applications have included thermodynamics properties of end-member phases and thermal elastic properties of end-member phases and few solid solutions. Extension of this software infrastructure to include other properties is in principle straightforward. This contribution will review the nature of results that can be generated (methods, thermodynamics domain, list of minerals, properties, etc) and nature of the software infrastructure. These applications are part of a more extensive cyber-infrastructure operating in the XSEDE - the VLab Science Gateway [1]. [1] https://www.xsede.org/web/guest/gateways-listing Research supported by NSF grants ATM-0428744 and EAR-1047629.

Deep Space Gateway Support of Lunar Surface Ops and Tele-Operational Transfer of Surface Assets to the Next Landing Site

NASA Astrophysics Data System (ADS)

Kring, D. A.

2018-02-01

The Deep Space Gateway can support astronauts on the lunar surface, providing them a departure and returning rendezvous point, a communication relay from the lunar farside to Earth, and a transfer point to Orion for return to Earth.

Analysis of random drop for gateway congestion control. M.S. Thesis

NASA Technical Reports Server (NTRS)

Hashem, Emam Salaheddin

1989-01-01

Lately, the growing demand on the Internet has prompted the need for more effective congestion control policies. Currently No Gateway Policy is used to relieve and signal congestion, which leads to unfair service to the individual users and a degradation of overall network performance. Network simulation was used to illustrate the character of Internet congestion and its causes. A newly proposed gateway congestion control policy, called Random Drop, was considered as a promising solution to the pressing problem. Random Drop relieves resource congestion upon buffer overflow by choosing a random packet from the service queue to be dropped. The random choice should result in a drop distribution proportional to the bandwidth distribution among all contending TCP connections, thus applying the necessary fairness. Nonetheless, the simulation experiments demonstrate several shortcomings with this policy. Because Random Drop is a congestion control policy, which is not applied until congestion has already occurred, it usually results in a high drop rate that hurts too many connections including well-behaved ones. Even though the number of packets dropped is different from one connection to another depending on the buffer utilization upon overflow, the TCP recovery overhead is high enough to neutralize these differences, causing unfair congestion penalties. Besides, the drop distribution itself is an inaccurate representation of the average bandwidth distribution, missing much important information about the bandwidth utilization between buffer overflow events. A modification of Random Drop to do congestion avoidance by applying the policy early was also proposed. Early Random Drop has the advantage of avoiding the high drop rate of buffer overflow. The early application of the policy removes the pressure of congestion relief and allows more accurate signaling of congestion. To be used effectively, algorithms for the dynamic adjustment of the parameters of Early Random Drop

Human resource solutions--the Gateway Paper proposed health reforms in Pakistan.

PubMed

Nishtar, Sania

2006-12-01

The existence of appropriate institutional and human resource capacity underpins the viability and sustainability of a health reform process within a country. Building human resource capacity within the health sector involves building the capacity of health service providers, health managers and administers as well as the stewards of health. Although capacity building is linked to a generic process closely linked to the broader economic, social and developmental context, it has specific health system connotations which should be the focus of a concerted effort. These include quantitative issues, in-effective deployment and brain-drain, qualitative considerations which stem from gaps in the quality of undergraduate as well as discrepancies in the content and format of training and absence of this in service of training health professionals and gaps in regulation. As one of the fundamental corner stones of health reform the Gateway Paper calls attention to the need to avert these issues with the development of a well-defined policy in human resource development as an entry point. This should be based on an analysis of the human resource need and should clearly define career structures for all categories of healthcare providers, and articulate the mechanisms of their effective deployment. Creating a conducive an rewarding environment, institutionalizing personnel management reform which go beyond personnel actions and set standards of performance, and develop appropriate incentives around this, would be critical. It would also be important to pay due attention to the content and format of training at an undergraduate level, at a postgraduate level and with reference to ongoing education and the allied roles of continuing medical education programs and accreditation of health systems educational institutions. The Gateway Paper also lays stress on effective regulation to curb the practice of quackery.

Gateways to clinical trials.

PubMed

Bayes, M; Rabasseda, X; Prous, J R

2006-01-01

Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs:(R)-Flurbiprofen, 90Yttrium-DOTA-huJ591; ABT-510, ACP-103, Ad5-FGF4, adalimumab, ademetionine, AG-7352, alemtuzumab, Amb a 1 ISS-DNA, anakinra, apaziquone, aprepitant, aripiprazole, atazanavir sulfate; BAL-8557, bevacizumab, BMS-188797, bortezomib, bosentan, brivudine; Calcipotriol/betamethasone dipropionate, cannabidiol, caspofungin acetate, catumaxomab, CERE-120, cetuximab, ciclesonide, cilomilast, cizolirtine citrate, Cypher, cystemustine; Dalbavancin, darifenacin hydrobromide, dasatinib, deferasirox, denosumab, desmoteplase, dihydrexidine, dimethyl fumarate, dutasteride, DW-166HC; Eculizumab, enfuvirtide, entecavir, epratuzumab, erlotinib hydrochloride, escitalopram oxalate, eszopiclone, etoricoxib, everolimus; Fallypride, febuxostat, fenretinide, fesoterodine, fingolimod hydrochloride; Gabapentin enacarbil, gefitinib; hMaxi-K, human papillomavirus vaccine, HYAL-CT1101; Imatinib mesylate, indiplon, inolimomab, ISAtx-247; J591; Lacosamide, landiolol, lasofoxifene tartrate, lestaurtinib, lidocaine/prilocaine, linezolid, lixivaptan, lonafarnib, lopinavir, lopinavir/ritonavir, lumiracoxib; Natalizumab, nesiritide; OC-108, omalizumab, onercept, OSC; Palifermin, palonosetron hydrochloride, parathyroid hormone (human recombinant), parecoxib sodium, PD-MAGE-3 vaccine, PEG-filgrastim, peginterferon alfa-2a, peginterferon alfa-2b, pegsunercept, pelitinib, pitavastatin calcium, plerixafor hydrochloride, posaconazole, prasterone sulfate, pregabalin; Ramelteon, ranelic acid distrontium salt, rasburicase, rosuvastatin calcium, rotigotine, RSD-1235, rufinamide, rupatadine fumarate; Sarizotan hydrochloride, SHL-749

Gateways to clinical trials.

PubMed

Bayés, M; Rabasseda, X; Prous, J R

2005-04-01

Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity. prous.com. This issue focuses on the following selection of drugs: ABX-IL-8, Acclaim, adalimumab, AGI-1067, alagebrium chloride, alemtuzumab, Alequel, Androgel, anti-IL-12 MAb, AOD-9604, aripiprazole, atomoxetine hydrochloride; Biphasic insulin aspart, bosentan, botulinum toxin type B, bovine lactoferrin, brivudine; Cantuzumab mertansine, CB-1954, CDB-4124, CEA-TRICOM, choriogonadotropin alfa, cilansetron, CpG-10101, CpG-7909, CTL-102, CTL-102/CB-1954; DAC:GRF, darbepoetin alfa, davanat-1, decitabine, del-1 Genemedicine, dexanabinol, dextofisopam, dnaJP1, dronedarone hydrochloride, dutasteride; Ecogramostim, eletriptan, emtricitabine, EPI-hNE-4, eplerenone, eplivanserin fumarate, erlotinib hydrochloride, ertapenem sodium, escitalopram oxalate, esomeprazole magnesium, etoricoxib, ezetimibe; Falecalcitriol, fingolimod hydrochloride; Gepirone hydrochloride; HBV-ISS, HSV-2 theracine, human insulin; Imatinib mesylate, Indiplon, insulin glargine, ISAtx-247; L612 HuMAb, levodopa/carbidopa/entacapone, lidocaine/prilocaine, LL-2113AD, lucinactant, LY-156735; Meclinertant, metelimumab, morphine hydrochloride, morphine-6-glucuronide; Natalizumab, nimotuzumab, NX-1207, NYVAC-HIV C; Omalizumab, onercept, osanetant; PABA, palosuran sulfate, parathyroid hormone (human recombinant), parecoxib sodium, PBI-1402, PCK-3145, peginterferon alfa-2a, peginterferon alfa-2b, peginterferon alfa-2b/ribavirin, pemetrexed disodium, pimecrolimus, PINC, pregabalin; Ramelteon, rasagiline mesilate, rasburicase, rimonabant hydrochloride, RO-0098557, rofecoxib, rosiglitazone maleate/metformin hydrochloride; Safinamide mesilate, SHL-749, sitaxsentan sodium, sparfosic acid, SprayGel, squalamine, St. John's Wort

GATEWAY Report Brief: Evaluating Tunable LED Lighting in the Swedish Medical Behavioral Health Unit

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

Summary of a GATEWAY report evaluation of a tunable LED lighting system installed in the new Swedish Medical Behavioral Health Unit in Seattle that incorporates color-tunable luminaires in common areas, and uses advanced controls for dimming and color tuning, with the goal of providing a better environment for staff and patients. The report reviews the design of the tunable lighting system, summarizes two sets of measurements, and discusses the circadian, energy, and commissioning implications as well as lessons learned from the project.

Using Instruments as Applied Science, Multipurpose Tools During Human Exploration: An XRD/XRF Demonstration Strategy for the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Bleacher, J. E.; Gendreau, K.; Arzoumanian, Z.; Young, K. E.; McAdam, A.

2018-02-01

Science instruments to be used during human exploration should be designed to serve as multipurpose tools that are of use throughout a mission. Here we discuss a multipurpose tool approach to using contact XRD/XRF onboard the Deep Space Gateway.

Design of a Golf Swing Injury Detection and Evaluation open service platform with Ontology-oriented clustering case-based reasoning mechanism.

PubMed

Ku, Hao-Hsiang

2015-01-01

Nowadays, people can easily use a smartphone to get wanted information and requested services. Hence, this study designs and proposes a Golf Swing Injury Detection and Evaluation open service platform with Ontology-oritened clustering case-based reasoning mechanism, which is called GoSIDE, based on Arduino and Open Service Gateway initative (OSGi). GoSIDE is a three-tier architecture, which is composed of Mobile Users, Application Servers and a Cloud-based Digital Convergence Server. A mobile user is with a smartphone and Kinect sensors to detect the user's Golf swing actions and to interact with iDTV. An application server is with Intelligent Golf Swing Posture Analysis Model (iGoSPAM) to check a user's Golf swing actions and to alter this user when he is with error actions. Cloud-based Digital Convergence Server is with Ontology-oriented Clustering Case-based Reasoning (CBR) for Quality of Experiences (OCC4QoE), which is designed to provide QoE services by QoE-based Ontology strategies, rules and events for this user. Furthermore, GoSIDE will automatically trigger OCC4QoE and deliver popular rules for a new user. Experiment results illustrate that GoSIDE can provide appropriate detections for Golfers. Finally, GoSIDE can be a reference model for researchers and engineers.

Linking Educational Research Activities across Europe: A Review of the WIFO Gateway to Research on Education in Europe

ERIC Educational Resources Information Center

Manning, Sabine

2007-01-01

The WIFO Gateway to Research on Education in Europe (http://www.wifo-gate.org) is an Internet portal focusing on vocational education and training and human resource development. Launched 10 years ago by the Research Forum Education and Society (Wissenschaftsforum Bildung und Gesellschaft-WIFO) Berlin, it has developed in several stages in close…

Gateway-Assisted Retransmission for Lightweight and Reliable IoT Communications.

PubMed

Chang, Hui-Ling; Wang, Cheng-Gang; Wu, Mong-Ting; Tsai, Meng-Hsun; Lin, Chia-Ying

2016-09-22

Message Queuing Telemetry Transport for Sensor Networks (MQTT-SN) and Constrained Application Protocol (CoAP) are two protocols supporting publish/subscribe models for IoT devices to publish messages to interested subscribers. Retransmission mechanisms are introduced to compensate for the lack of data reliability. If the device does not receive the acknowledgement (ACK) before retransmission timeout (RTO) expires, the device will retransmit data. Setting an appropriate RTO is important because the delay may be large or retransmission may be too frequent when the RTO is inappropriate. We propose a Gateway-assisted CoAP (GaCoAP) to dynamically compute RTO for devices. Simulation models are proposed to investigate the performance of GaCoAP compared with four other methods. The experiment results show that GaCoAP is more suitable for IoT devices.

Multifunctional Interface Facility for Receiving and Processing Planetary Surface Materials for Science Investigation and Resource Evaluation at the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Sibille, L.; Mantovani, J. G.; Townsend, I. I.; Mueller, R. P.

2018-02-01

The concepts describe hardware and instrumentation for the study of planetary surface materials at the Deep Space Gateway as a progressive evolution of capabilities for eliminating the need for special handling and Planetary Protection (PP) protocols inside the habitats.

The Climate-G Portal: a Grid Enabled Scientifc Gateway for Climate Change

NASA Astrophysics Data System (ADS)

Fiore, Sandro; Negro, Alessandro; Aloisio, Giovanni

2010-05-01

Grid portals are web gateways aiming at concealing the underlying infrastructure through a pervasive, transparent, user-friendly, ubiquitous and seamless access to heterogeneous and geographical spread resources (i.e. storage, computational facilities, services, sensors, network, databases). Definitively they provide an enhanced problem-solving environment able to deal with modern, large scale scientific and engineering problems. Scientific gateways are able to introduce a revolution in the way scientists and researchers organize and carry out their activities. Access to distributed resources, complex workflow capabilities, and community-oriented functionalities are just some of the features that can be provided by such a web-based environment. In the context of the EGEE NA4 Earth Science Cluster, Climate-G is a distributed testbed focusing on climate change research topics. The Euro-Mediterranean Center for Climate Change (CMCC) is actively participating in the testbed providing the scientific gateway (Climate-G Portal) to access to the entire infrastructure. The Climate-G Portal has to face important and critical challenges as well as has to satisfy and address key requirements. In the following, the most relevant ones are presented and discussed. Transparency: the portal has to provide a transparent access to the underlying infrastructure preventing users from dealing with low level details and the complexity of a distributed grid environment. Security: users must be authenticated and authorized on the portal to access and exploit portal functionalities. A wide set of roles is needed to clearly assign the proper one to each user. The access to the computational grid must be completely secured, since the target infrastructure to run jobs is a production grid environment. A security infrastructure (based on X509v3 digital certificates) is strongly needed. Pervasivity and ubiquity: the access to the system must be pervasive and ubiquitous. This is easily true due

D1/D5 Receptors and Histone Deacetylation Mediate the Gateway Effect of LTP in Hippocampal Dentate Gyrus

ERIC Educational Resources Information Center

Huang, Yan-You; Lavine, Amir; Kandel, Denise B.; Yin, Deqi; Colnaghi, Luca; Drisaldi, Bettina; Kandel, Eric R.

2014-01-01

The dentate gyrus (DG) of the hippocampus is critical for spatial memory and is also thought to be involved in the formation of drug-related associative memory. Here, we attempt to test an aspect of the Gateway Hypothesis, by studying the effect of consecutive exposure to nicotine and cocaine on long-term synaptic potentiation (LTP) in the DG. We…

Systematic cloning of an ORFeome using the Gateway system.

PubMed

Matsuyama, Akihisa; Yoshida, Minoru

2009-01-01

With the completion of the genome projects, there are increasing demands on the experimental systems that enable to exploit the entire set of protein-coding open reading frames (ORFs), viz. ORFeome, en masse. Systematic proteomic studies based on cloned ORFeomes are called "reverse proteomics," and have been launched in many organisms in recent years. Cloning of an ORFeome is such an attractive way for comprehensive understanding of biological phenomena, but is a challenging and daunting task. However, recent advances in techniques for DNA cloning using site-specific recombination and for high-throughput experimental techniques have made it feasible to clone an ORFeome with the minimum of exertion. The Gateway system is one of such the approaches, employing the recombination reaction of the bacteriophage lambda. Combining traditional DNA manipulation methods with modern technique of the recombination-based cloning system, it is possible to clone an ORFeome of an organism on an individual level.

Intelligent Document Gateway: A Service System Case Study and Analysis

NASA Astrophysics Data System (ADS)

Krishna, Vikas; Lelescu, Ana

In today's fast paced world, it is necessary to process business ­documents expediently, accurately, and diligently. In other words, processing has to be fast, errors must be prevented (or caught and corrected quickly), and documents cannot be lost or misplaced. The failure to meet these criteria, depending on the type and purpose of the documents, can have serious business, legal, or safety consequences. In this paper, we evaluated a B2B order placement service system that allows clients to place orders for products and services over a network. We describe the order placement service before and after deploying the Intelligent Document Gateway (IDG), a document-centric business process automation technology from IBM Research. Using service science perspective and service systems frameworks, we provide an analysis of how IDG improved the value proposition for both the service providers and service clients.

Gateway-Assisted Retransmission for Lightweight and Reliable IoT Communications

PubMed Central

Chang, Hui-Ling; Wang, Cheng-Gang; Wu, Mong-Ting; Tsai, Meng-Hsun; Lin, Chia-Ying

2016-01-01

Message Queuing Telemetry Transport for Sensor Networks (MQTT-SN) and Constrained Application Protocol (CoAP) are two protocols supporting publish/subscribe models for IoT devices to publish messages to interested subscribers. Retransmission mechanisms are introduced to compensate for the lack of data reliability. If the device does not receive the acknowledgement (ACK) before retransmission timeout (RTO) expires, the device will retransmit data. Setting an appropriate RTO is important because the delay may be large or retransmission may be too frequent when the RTO is inappropriate. We propose a Gateway-assisted CoAP (GaCoAP) to dynamically compute RTO for devices. Simulation models are proposed to investigate the performance of GaCoAP compared with four other methods. The experiment results show that GaCoAP is more suitable for IoT devices. PMID:27669243

Milankovitch forcing and role of Indonesian Gateway on middle Miocene climate and carbon cycle: New perspective from the South China Sea, equatorial West Pacific and East Indian Ocean

NASA Astrophysics Data System (ADS)

Holbourn, A.; Kuhnt, W.; Schulz, M.

2003-04-01

The enigmatic long-term positive carbon isotope excursion ("Monterey excursion") in the middle Miocene exhibits an apparent 400 ky cyclicity (long eccentricity cycle of the Milankovitch frequency band). Similar isotope excursion are known from the mid-Cretaceous and may be a characteristic feature of a greenhouse world with extreme warm climate, high sealevel, and a dominantly zonal circulation pattern in the world ocean. This period of extreme warmth (the mid-Miocene climate optimum) ended between 14.2 and 13.8 Ma, when a significant increase in deep-water oxygen isotopic values occurred that was related to the growth of the East Antarctic ice sheet. Plate tectonic movements between Australia and SE Asia, ultimately leading to the closure of the deep water gateway connecting the Indian and Pacific Oceans, started prior to this paleoceanographic change. We used benthic deep water oxygen and carbon isotope curves in combination with new age models at critical locations along the northern margin of the Indonesian Gateway (South China Sea, ODP Site 1146), at the western end of the gateway (NW Australian margin, ODP Site 761) and at the eastern end of the gateway (Ontong Java Plateau, ODP Site 806) to investigate the frequency and amplitude of deep water isotope fluctuations during the middle Miocene. High resolution sediment color reflectance data, benthic carbon isotopes and foraminiferal assemblages are used as proxies of deep-water ventilation and carbon flux. Our results indicate Milankovitch forcing on virtually all proxies and a change from eccentricity to precession driven cyclicity at approximately 15 Ma. Our data reveal increased carbon flux and a restricted deep water exchange between the Pacific Ocean and Indian Ocean through the Indonesian Gateway during the middle Miocene climate optimum. After 13.6 Ma, the decrease in d13C was strongest at Site 806, indicating a marked change in the deep-water circulation of the equatorial West Pacific and a switch to a

WRF4SG: A Scientific Gateway for climate experiment workflows

NASA Astrophysics Data System (ADS)

Blanco, Carlos; Cofino, Antonio S.; Fernandez-Quiruelas, Valvanuz

2013-04-01

The Weather Research and Forecasting model (WRF) is a community-driven and public domain model widely used by the weather and climate communities. As opposite to other application-oriented models, WRF provides a flexible and computationally-efficient framework which allows solving a variety of problems for different time-scales, from weather forecast to climate change projection. Furthermore, WRF is also widely used as a research tool in modeling physics, dynamics, and data assimilation by the research community. Climate experiment workflows based on Weather Research and Forecasting (WRF) are nowadays among the one of the most cutting-edge applications. These workflows are complex due to both large storage and the huge number of simulations executed. In order to manage that, we have developed a scientific gateway (SG) called WRF for Scientific Gateway (WRF4SG) based on WS-PGRADE/gUSE and WRF4G frameworks to ease achieve WRF users needs (see [1] and [2]). WRF4SG provides services for different use cases that describe the different interactions between WRF users and the WRF4SG interface in order to show how to run a climate experiment. As WS-PGRADE/gUSE uses portlets (see [1]) to interact with users, its portlets will support these use cases. A typical experiment to be carried on by a WRF user will consist on a high-resolution regional re-forecast. These re-forecasts are common experiments used as input data form wind power energy and natural hazards (wind and precipitation fields). In the cases below, the user is able to access to different resources such as Grid due to the fact that WRF needs a huge amount of computing resources in order to generate useful simulations: * Resource configuration and user authentication: The first step is to authenticate on users' Grid resources by virtual organizations. After login, the user is able to select which virtual organization is going to be used by the experiment. * Data assimilation: In order to assimilate the data sources

Gateway Effects: Why the Cited Evidence Does Not Support Their Existence for Low-Risk Tobacco Products (and What Evidence Would).

PubMed

Phillips, Carl V

2015-05-21

It is often claimed that low-risk drugs still create harm because of "gateway effects", in which they cause the use of a high-risk alternative. Such claims are popular among opponents of tobacco harm reduction, claiming that low-risk tobacco products (e.g., e-cigarettes, smokeless tobacco) cause people to start smoking, sometimes backed by empirical studies that ostensibly support the claim. However, these studies consistently ignore the obvious alternative causal pathways, particularly that observed associations might represent causation in the opposite direction (smoking causes people to seek low-risk alternatives) or confounding (the same individual characteristics increase the chance of using any tobacco product). Due to these complications, any useful analysis must deal with simultaneity and confounding by common cause. In practice, existing analyses seem almost as if they were designed to provide teaching examples about drawing simplistic and unsupported causal conclusions from observed associations. The present analysis examines what evidence and research strategies would be needed to empirically detect such a gateway effect, if there were one, explaining key methodological concepts including causation and confounding, examining the logic of the claim, identifying potentially useful data, and debunking common fallacies on both sides of the argument, as well as presenting an extended example of proper empirical testing. The analysis demonstrates that none of the empirical studies to date that are purported to show a gateway effect from tobacco harm reduction products actually does so. The observations and approaches can be generalized to other cases where observed association of individual characteristics in cross-sectional data could result from any of several causal relationships.

Gateway Effects: Why the Cited Evidence Does Not Support Their Existence for Low-Risk Tobacco Products (and What Evidence Would)

PubMed Central

Phillips, Carl V.

2015-01-01

It is often claimed that low-risk drugs still create harm because of “gateway effects”, in which they cause the use of a high-risk alternative. Such claims are popular among opponents of tobacco harm reduction, claiming that low-risk tobacco products (e.g., e-cigarettes, smokeless tobacco) cause people to start smoking, sometimes backed by empirical studies that ostensibly support the claim. However, these studies consistently ignore the obvious alternative causal pathways, particularly that observed associations might represent causation in the opposite direction (smoking causes people to seek low-risk alternatives) or confounding (the same individual characteristics increase the chance of using any tobacco product). Due to these complications, any useful analysis must deal with simultaneity and confounding by common cause. In practice, existing analyses seem almost as if they were designed to provide teaching examples about drawing simplistic and unsupported causal conclusions from observed associations. The present analysis examines what evidence and research strategies would be needed to empirically detect such a gateway effect, if there were one, explaining key methodological concepts including causation and confounding, examining the logic of the claim, identifying potentially useful data, and debunking common fallacies on both sides of the argument, as well as presenting an extended example of proper empirical testing. The analysis demonstrates that none of the empirical studies to date that are purported to show a gateway effect from tobacco harm reduction products actually does so. The observations and approaches can be generalized to other cases where observed association of individual characteristics in cross-sectional data could result from any of several causal relationships. PMID:26006122

The Deep Space Gateway Lightning Mapper (DLM) - Monitoring Global Change and Thunderstorm Processes Through Observations of Earth's High-Latitude Lightning from Cis-Lunar Orbit

NASA Technical Reports Server (NTRS)

Lang, Timothy; Blakeslee, R. J.; Cecil, D. J.; Christian, H. J.; Gatlin, P. N.; Goodman, S. J.; Koshak, W. J.; Petersen, W. A.; Quick, M.; Schultz, C. J.;

Gateways to clinical trials.

PubMed

Bayes, M; Rabasseda, X; Prous, J R

2006-03-01

Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: 131I-labetuzumab; Abacavir sulfate, abatacept, adalimumab, ademetionine, adjuvanted influenza vaccine, alefacept, alemtuzumab, amlodipine, amphotericin B, anakinra, aripiprazole, aspirin, axitinib; Betamethasone dipropionate, bevacizumab, biphasic insulin aspart, bortezomib, bosentan, botulinum toxin type B, BQ-123; Calcium folinate, canertinib dihydrochloride, carboplatin, carmustine, cetirizine hydrochloride, cetuximab, cholecalciferol, ciclesonide, ciclosporin, cinacalcet hydrochloride, cisplatin, clarithromycin, clofazimine, cold-adapted influenza vaccine trivalent, CpG-7909; Darbepoetin alfa, darifenacin hydrobromide, DB-289, desloratadine, Dexamet, dicycloverine hydrochloride, dimethyl fumarate, docetaxel, dolastatin 10, drospirenone, drospirenone/estradiol, duloxetine hydrochloride; Ecogramostim, edotecarin, efaproxiral sodium, enalapril maleate, epoetin beta, epoprostenol sodium, epratuzumab, erlotinib hydrochloride, escitalopram oxalate, estradiol, etanercept; Fluconazole, fludarabine phosphate, fluorouracil; Gefitinib, gemcitabine, Ghrelin (human), glibenclamide, glimepiride, GTI-2040; Haloperidol, human insulin, hydrocortisone probutate; Imatinib mesylate, indisulam, influenza vaccine, inhaled insulin, insulin aspart, insulin glulisine, insulin lispro, irinotecan, ispronicline; Lamivudine, lamivudine/zidovudine/abacavir sulfate, lapatinib, letrozole, levocetirizine, lomustine, lonafarnib, lumiracoxib;Magnesium sulfate, MD-1100, melphalan, metformin hydrochloride, methotrexate, metoclopramide hydrochloride, mitiglinide calcium hydrate, monophosphoryl lipid A, montelukast sodium, motexafin gadolinium

Gateways to clinical trials.

PubMed

Bayes, M; Rabasseda, X; Prous, J R

2005-10-01

Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: (-)-Epigallocatechin gallate, (Z)-4-hydroxytamoxifen; Ad.muIFN-beta AD-237, adalimumab, adefovir dipivoxil, agalsidase alfa, alemtuzumab, almotriptan, ALVAC vCP1452, alvimopan hydrate, ambrisentan, anakinra, anti-IFN-gamma MAb; Bimatoprost, BMS-188797, BMS-214662, bortezomib, bosentan, bovine lactoferrin; Caffeine, canertinib dihydrochloride, canfosfamide hydrochloride, cannabidiol, caspofungin acetate, cetuximab, cH36, ChimeriVax-JE, ciclesonide, cilansetron, cinacalcet hydrochloride, clopidogrel, CpG-7909, Cypher; Daptomycin, darbepoetin alfa, darifenacin hydrobromide, decitabine, denufosol tetrasodium, Dexamet, diindolemethane, drotrecogin alfa (activated), duloxetine hydrochloride, DX-9065a; E-7010, edaravone, efalizumab, eicosapentaenoic acid/docosahexaenoic acid, elacridar, eletriptan, emtricitabine, epratuzumab, erlotinib hydrochloride, ertapenem sodium, eszopiclone, everolimus, ezetimibe; Fludarabine, fondaparinux sodium; gamma-Hydroxybutyrate sodium, gavestinel sodium, gefitinib, granisetron-Biochronomer; Human Albumin, human insulin; Imatinib mesylate, indiplon, interleukin-2 XL, isatoribine, ISS-1018, i.v. gamma-globulin, ivabradine hydrochloride, ixabepilone; Lanthanum carbonate, L-arginine hydrochloride, liposomal doxorubicin, LY-450139; Magnesium sulfate, melatonin, motexafin gadolinium, mycophenolic acid sodium salt; Natalizumab, nesiritide, niacin/lovastatin; OGX-011, olmesartan medoxomil, omalizumab, ospemifene; PACAP38, panitumumab, parathyroid hormone (human recombinant), parecoxib sodium, patupilone, pegfilgrastim, peginterferon alfa-2a, peginterferon alfa-2b, peginterferon alfa-2b

Scalable Conjunction Processing using Spatiotemporally Indexed Ephemeris Data

NASA Astrophysics Data System (ADS)

Budianto-Ho, I.; Johnson, S.; Sivilli, R.; Alberty, C.; Scarberry, R.

2014-09-01

The collision warnings produced by the Joint Space Operations Center (JSpOC) are of critical importance in protecting U.S. and allied spacecraft against destructive collisions and protecting the lives of astronauts during space flight. As the Space Surveillance Network (SSN) improves its sensor capabilities for tracking small and dim space objects, the number of tracked objects increases from thousands to hundreds of thousands of objects, while the number of potential conjunctions increases with the square of the number of tracked objects. Classical filtering techniques such as apogee and perigee filters have proven insufficient. Novel and orders of magnitude faster conjunction analysis algorithms are required to find conjunctions in a timely manner. Stellar Science has developed innovative filtering techniques for satellite conjunction processing using spatiotemporally indexed ephemeris data that efficiently and accurately reduces the number of objects requiring high-fidelity and computationally-intensive conjunction analysis. Two such algorithms, one based on the k-d Tree pioneered in robotics applications and the other based on Spatial Hash Tables used in computer gaming and animation, use, at worst, an initial O(N log N) preprocessing pass (where N is the number of tracked objects) to build large O(N) spatial data structures that substantially reduce the required number of O(N^2) computations, substituting linear memory usage for quadratic processing time. The filters have been implemented as Open Services Gateway initiative (OSGi) plug-ins for the Continuous Anomalous Orbital Situation Discriminator (CAOS-D) conjunction analysis architecture. We have demonstrated the effectiveness, efficiency, and scalability of the techniques using a catalog of 100,000 objects, an analysis window of one day, on a 64-core computer with 1TB shared memory. Each algorithm can process the full catalog in 6 minutes or less, almost a twenty-fold performance improvement over the

An Intelligent Cloud Storage Gateway for Medical Imaging.

PubMed

Viana-Ferreira, Carlos; Guerra, António; Silva, João F; Matos, Sérgio; Costa, Carlos

2017-09-01

Historically, medical imaging repositories have been supported by indoor infrastructures. However, the amount of diagnostic imaging procedures has continuously increased over the last decades, imposing several challenges associated with the storage volume, data redundancy and availability. Cloud platforms are focused on delivering hardware and software services over the Internet, becoming an appealing solution for repository outsourcing. Although this option may bring financial and technological benefits, it also presents new challenges. In medical imaging scenarios, communication latency is a critical issue that still hinders the adoption of this paradigm. This paper proposes an intelligent Cloud storage gateway that optimizes data access times. This is achieved through a new cache architecture that combines static rules and pattern recognition for eviction and prefetching. The evaluation results, obtained from experiments over a real-world dataset, show that cache hit ratios can reach around 80%, leading to reductions of image retrieval times by over 60%. The combined use of eviction and prefetching policies proposed can significantly reduce communication latency, even when using a small cache in comparison to the total size of the repository. Apart from the performance gains, the proposed system is capable of adjusting to specific workflows of different institutions.

GermOnline 4.0 is a genomics gateway for germline development, meiosis and the mitotic cell cycle.

PubMed

Lardenois, Aurélie; Gattiker, Alexandre; Collin, Olivier; Chalmel, Frédéric; Primig, Michael

2010-01-01

GermOnline 4.0 is a cross-species database portal focusing on high-throughput expression data relevant for germline development, the meiotic cell cycle and mitosis in healthy versus malignant cells. It is thus a source of information for life scientists as well as clinicians who are interested in gene expression and regulatory networks. The GermOnline gateway provides unlimited access to information produced with high-density oligonucleotide microarrays (3'-UTR GeneChips), genome-wide protein-DNA binding assays and protein-protein interaction studies in the context of Ensembl genome annotation. Samples used to produce high-throughput expression data and to carry out genome-wide in vivo DNA binding assays are annotated via the MIAME-compliant Multiomics Information Management and Annotation System (MIMAS 3.0). Furthermore, the Saccharomyces Genomics Viewer (SGV) was developed and integrated into the gateway. SGV is a visualization tool that outputs genome annotation and DNA-strand specific expression data produced with high-density oligonucleotide tiling microarrays (Sc_tlg GeneChips) which cover the complete budding yeast genome on both DNA strands. It facilitates the interpretation of expression levels and transcript structures determined for various cell types cultured under different growth and differentiation conditions. Database URL: www.germonline.org/

GermOnline 4.0 is a genomics gateway for germline development, meiosis and the mitotic cell cycle

PubMed Central

Lardenois, Aurélie; Gattiker, Alexandre; Collin, Olivier; Chalmel, Frédéric; Primig, Michael

2010-01-01

GermOnline 4.0 is a cross-species database portal focusing on high-throughput expression data relevant for germline development, the meiotic cell cycle and mitosis in healthy versus malignant cells. It is thus a source of information for life scientists as well as clinicians who are interested in gene expression and regulatory networks. The GermOnline gateway provides unlimited access to information produced with high-density oligonucleotide microarrays (3′-UTR GeneChips), genome-wide protein–DNA binding assays and protein–protein interaction studies in the context of Ensembl genome annotation. Samples used to produce high-throughput expression data and to carry out genome-wide in vivo DNA binding assays are annotated via the MIAME-compliant Multiomics Information Management and Annotation System (MIMAS 3.0). Furthermore, the Saccharomyces Genomics Viewer (SGV) was developed and integrated into the gateway. SGV is a visualization tool that outputs genome annotation and DNA-strand specific expression data produced with high-density oligonucleotide tiling microarrays (Sc_tlg GeneChips) which cover the complete budding yeast genome on both DNA strands. It facilitates the interpretation of expression levels and transcript structures determined for various cell types cultured under different growth and differentiation conditions. Database URL: www.germonline.org/ PMID:21149299

Building a Gateway for the CD-ROM Network: A Step toward the Virtual Library with the Virtual Microsystems V-Server.

ERIC Educational Resources Information Center

Sylvia, Margaret

1993-01-01

Describes one college library's experience with a gateway for dial-in access to its CD-ROM network to increase access to automated index searching for students off-campus. Hardware and software choices are discussed in terms of access, reliability, affordability, and ease of use. Installation problems are discussed, and an appendix lists product…

Wikipedia as a gateway to biomedical research: The relative distribution and use of citations in the English Wikipedia.

PubMed

Maggio, Lauren A; Willinsky, John M; Steinberg, Ryan M; Mietchen, Daniel; Wass, Joseph L; Dong, Ting

2017-01-01

Wikipedia is a gateway to knowledge. However, the extent to which this gateway ends at Wikipedia or continues via supporting citations is unknown. Wikipedia's gateway functionality has implications for information design and education, notably in medicine. This study aims to establish benchmarks for the relative distribution and referral (click) rate of citations-as indicated by presence of a Digital Object Identifier (DOI)-from Wikipedia, with a focus on medical citations. DOIs referred from the English Wikipedia in August 2016 were obtained from Crossref.org. Next, based on a DOI's presence on a WikiProject Medicine page, all DOIs in Wikipedia were categorized as medical (WP:MED) or non-medical (non-WP:MED). Using this categorization, referred DOIs were classified as WP:MED, non-WP:MED, or BOTH, meaning the DOI may have been referred from either category. Data were analyzed using descriptive and inferential statistics. Out of 5.2 million Wikipedia pages, 4.42% (n = 229,857) included at least one DOI. 68,870 were identified as WP:MED, with 22.14% (n = 15,250) featuring one or more DOIs. WP:MED pages featured on average 8.88 DOI citations per page, whereas non-WP:MED pages had on average 4.28 DOI citations. For DOIs only on WP:MED pages, a DOI was referred every 2,283 pageviews and for non-WP:MED pages every 2,467 pageviews. DOIs from BOTH pages accounted for 12% (n = 58,475). The referral of DOI citations found in BOTH could not be assigned to WP:MED or non-WP:MED, as the page from which the referral was made was not provided with the data. While these results cannot provide evidence of greater citation referral from WP:MED than non-WP:MED, they do provide benchmarks to assess strategies for changing referral patterns. These changes might include editors adopting new methods for designing and presenting citations or the introduction of teaching strategies that address the value of consulting citations as a tool for extending learning.

Wikipedia as a gateway to biomedical research: The relative distribution and use of citations in the English Wikipedia

PubMed Central

Willinsky, John M.; Steinberg, Ryan M.; Mietchen, Daniel; Wass, Joseph L.; Dong, Ting

2017-01-01

Wikipedia is a gateway to knowledge. However, the extent to which this gateway ends at Wikipedia or continues via supporting citations is unknown. Wikipedia’s gateway functionality has implications for information design and education, notably in medicine. This study aims to establish benchmarks for the relative distribution and referral (click) rate of citations—as indicated by presence of a Digital Object Identifier (DOI)—from Wikipedia, with a focus on medical citations. DOIs referred from the English Wikipedia in August 2016 were obtained from Crossref.org. Next, based on a DOI’s presence on a WikiProject Medicine page, all DOIs in Wikipedia were categorized as medical (WP:MED) or non-medical (non-WP:MED). Using this categorization, referred DOIs were classified as WP:MED, non-WP:MED, or BOTH, meaning the DOI may have been referred from either category. Data were analyzed using descriptive and inferential statistics. Out of 5.2 million Wikipedia pages, 4.42% (n = 229,857) included at least one DOI. 68,870 were identified as WP:MED, with 22.14% (n = 15,250) featuring one or more DOIs. WP:MED pages featured on average 8.88 DOI citations per page, whereas non-WP:MED pages had on average 4.28 DOI citations. For DOIs only on WP:MED pages, a DOI was referred every 2,283 pageviews and for non-WP:MED pages every 2,467 pageviews. DOIs from BOTH pages accounted for 12% (n = 58,475). The referral of DOI citations found in BOTH could not be assigned to WP:MED or non-WP:MED, as the page from which the referral was made was not provided with the data. While these results cannot provide evidence of greater citation referral from WP:MED than non-WP:MED, they do provide benchmarks to assess strategies for changing referral patterns. These changes might include editors adopting new methods for designing and presenting citations or the introduction of teaching strategies that address the value of consulting citations as a tool for extending learning. PMID:29267345

Note: Methodology for the analysis of Bluetooth gateways in an implemented scatternet.

PubMed

Etxaniz, J; Monje, P M; Aranguren, G

2014-03-01

This Note introduces a novel methodology to analyze the time performance of Bluetooth gateways in multi-hop networks, known as scatternets. The methodology is focused on distinguishing between the processing time and the time that each communication between nodes takes along an implemented scatternet. This technique is not only valid for Bluetooth networks but also for other wireless networks that offer access to their middleware in order to include beacons in the operation of the nodes. We show in this Note the results of the tests carried out on a Bluetooth scatternet in order to highlight the reliability and effectiveness of the methodology. The results also validate this technique showing convergence in the results when subtracting the time for the beacons from the delay measurements.

Cataloguing and displaying Web feeds from French language health sites: a Web 2.0 add-on to a health gateway.

PubMed

Kerdelhué, G; Thirion, B; Dahamna, B; Darmoni, S J

2008-01-01

Among the numerous new functionalities of the Internet, commonly called Web 2.0, Web syndication illustrates the trend for better and faster information sharing. Web feeds (a.k.a RSS feeds), which were used mostly on weblogs at first, are now also widely used in academic, scientific and institutional websites such as PubMed. As very few French language feeds were listed or catalogued in the Health field by the year of 2007, it was decided to implement them in the quality-controlled health gateway CISMeF ([French] acronym for Catalogue and Index of French Language Health Resources on the Internet). Furthermore, making full use of the nature of Web syndication, a Web feed aggregator was put online in to provide a dynamic news gateway called "CISMeF actualités" (http://www.chu-rouen.fr/actualites/). This article describes the process to retrieve and implement the Web feeds in the catalogue and how its terminology was adjusted to describe this new content. It also describes how the aggregator was put online and the features of this news gateway. CISMeF actualités was built accordingly to the editorial policy of CISMeF. Only a part of the Web feeds of the catalogue were included to display the most authoritative sources. Web feeds were also grouped by medical specialties and by countries using the prior indexing of websites with MeSH terms and the so-called metaterms. CISMeF actualités now displays 131 Web feeds across 40 different medical specialities, coming from 5 different countries. It is one example, among many, that static hypertext links can now easily and beneficially be completed, or replaced, by dynamic display of Web content using syndication feeds.

Patterns in Crew-Initiated Photography of Earth from ISS - Is Earth Observation a Salutogenic Experience?

NASA Technical Reports Server (NTRS)

Robinson, Julie A.; Slack, Kelley; Olson, V.; Trenchard, M.; Willis, K.; Baskin, P.

2006-01-01

This viewgraph presentation asks the question "Is the observation of earth from the ISS a positive (salutogenic) experience for crew members?"All images are distributed to the public via the "Gateway to Astronaut Photography of Earth at http://eol.jsc.nasa.gov. The objectives of the study are (1) Mine the dataset of Earth Observation photography--What can it tell us about the importance of viewing the Earth as a positive experience for the crewmembers? (2) Quantify extent to which photography was self-initiated (not requested by scientists) (3) Identify patterns photography activities versus scientific requested photography.

Draft Permit & Supporting Documentation for the Northeast Gateway Energy Bridge Deepwater Port, Federal Waters of Massachusetts Bay (Modification to Existing Permit LNG Regasification Vessel/DWP Project)

EPA Pesticide Factsheets

List of draft permit & supporting documentation for the Northeast Gateway Energy Bridge Deepwater Port, Federal Waters of Massachusetts Bay (Modification to Existing Permit LNG Regasification Vessel/DWP Project).

Comparing Trash Disposal and Reuse Options for Deep Space Gateway and Mars Missions

NASA Technical Reports Server (NTRS)

Ewert, Michael; Broyan, James; Goodliff, Kandyce; Clowdsley, Martha; Singleterry, Robert

2017-01-01

Taking out the trash at NASA's newly proposed Deep Space Gateway (DSG) will not be a trivial task. While not the most important aspect of planning this cislunar outpost, there are several options that should be carefully considered since they may affect the crew as well as mission mass and volume. This study extends an earlier one, which focused on waste disposal options for a Mars Transit Vehicle. In that study, gasifying and venting trash along the way was found to noticeably reduce propellant needs and launch mass, whereas keeping processed trash on board in the form of radiation shielding tiles would significantly lower the crew's radiation dose during a solar particle event. Another favorable strategy was packing trash in a used logistics module for disposal. Since the DSG does not need much propulsion to maintain its orbit and Orion will be present with its own radiation storm shelter at the Gateway, the driving factors of the waste disposal trade study are different than for the Mars mission. Besides reviewing the propulsion and radiation shielding factors, potential drivers such as mass, power, volume, crew time, and human factors (e.g. smell) were studied. Disposal options for DSG include jettison of a used logistics module containing waste after every human stay, jettison of the same logistics module after several missions once it is full, regular disposal of trash via an airlock, or gasifying waste products for easier disposal or reuse. Conversely, a heat melt compactor device could be used to remove water and stabilize trash into tiles which could be more compactly stored on board and used as radiation shielding. Equivalent system mass analysis is used to tally the benefits and costs (mass, volume, power, crew time) of each case on an equivalent mass basis. Other more subjective factors are also discussed. Recommendations are made for DSG and Mars mission waste disposal.

Volcano Modelling and Simulation gateway (VMSg): A new web-based framework for collaborative research in physical modelling and simulation of volcanic phenomena

NASA Astrophysics Data System (ADS)

Esposti Ongaro, T.; Barsotti, S.; de'Michieli Vitturi, M.; Favalli, M.; Longo, A.; Nannipieri, L.; Neri, A.; Papale, P.; Saccorotti, G.

2009-12-01

Physical and numerical modelling is becoming of increasing importance in volcanology and volcanic hazard assessment. However, new interdisciplinary problems arise when dealing with complex mathematical formulations, numerical algorithms and their implementations on modern computer architectures. Therefore new frameworks are needed for sharing knowledge, software codes, and datasets among scientists. Here we present the Volcano Modelling and Simulation gateway (VMSg, accessible at http://vmsg.pi.ingv.it), a new electronic infrastructure for promoting knowledge growth and transfer in the field of volcanological modelling and numerical simulation. The new web portal, developed in the framework of former and ongoing national and European projects, is based on a dynamic Content Manager System (CMS) and was developed to host and present numerical models of the main volcanic processes and relationships including magma properties, magma chamber dynamics, conduit flow, plume dynamics, pyroclastic flows, lava flows, etc. Model applications, numerical code documentation, simulation datasets as well as model validation and calibration test-cases are also part of the gateway material.

An exploration of the gateway math and science course relationships in the Los Angeles Community College District

NASA Astrophysics Data System (ADS)

Buchanan, Donald G.

This study evaluated selected demographic, pre-enrollment, and economic status variables in comparison to college-level performance factors of GPA and course completion ratios for gateway math and science courses. The Transfer and Retention of Urban Community College Students (TRUCCS) project team collected survey and enrollment data for this study in the Los Angeles Community College District (LACCD). The TRUCCS team surveyed over 5,000 students within the nine campus district beginning in the fall of 2000 and spring of 2001 with follow-up data for next several years. This study focused on the math and science courses; established background demographics; evaluated pre-enrollment high school self-reported grades; reviewed high school and college level math courses taken; investigated specific gateway courses of biology, chemistry and physics; and compared them to the overall GPAs and course completion ratios for 4,698 students. This involved the SPSS development of numerous statistical products including the data from frequency distributions, means, cross-tabulations, group statistics t-tests, independent samples t-tests, and one-way ANOVA. Findings revealed demographic and economic relationships of significance for students' performance factors of GPA and course completion ratios. Furthermore, findings revealed significant differences between the gender, age, ethnicity and economic employment relationships. Conclusions and implications for institutions of higher education were documented. Recommendations for dissemination, intervention programs, and future research were also discussed.

The Einstein Genome Gateway using WASP - a high throughput multi-layered life sciences portal for XSEDE.

PubMed

Golden, Aaron; McLellan, Andrew S; Dubin, Robert A; Jing, Qiang; O Broin, Pilib; Moskowitz, David; Zhang, Zhengdong; Suzuki, Masako; Hargitai, Joseph; Calder, R Brent; Greally, John M

2012-01-01

Massively-parallel sequencing (MPS) technologies and their diverse applications in genomics and epigenomics research have yielded enormous new insights into the physiology and pathophysiology of the human genome. The biggest hurdle remains the magnitude and diversity of the datasets generated, compromising our ability to manage, organize, process and ultimately analyse data. The Wiki-based Automated Sequence Processor (WASP), developed at the Albert Einstein College of Medicine (hereafter Einstein), uniquely manages to tightly couple the sequencing platform, the sequencing assay, sample metadata and the automated workflows deployed on a heterogeneous high performance computing cluster infrastructure that yield sequenced, quality-controlled and 'mapped' sequence data, all within the one operating environment accessible by a web-based GUI interface. WASP at Einstein processes 4-6 TB of data per week and since its production cycle commenced it has processed ~ 1 PB of data overall and has revolutionized user interactivity with these new genomic technologies, who remain blissfully unaware of the data storage, management and most importantly processing services they request. The abstraction of such computational complexity for the user in effect makes WASP an ideal middleware solution, and an appropriate basis for the development of a grid-enabled resource - the Einstein Genome Gateway - as part of the Extreme Science and Engineering Discovery Environment (XSEDE) program. In this paper we discuss the existing WASP system, its proposed middleware role, and its planned interaction with XSEDE to form the Einstein Genome Gateway.

The VERCE platform: Enabling Computational Seismology via Streaming Workflows and Science Gateways

NASA Astrophysics Data System (ADS)

Spinuso, Alessandro; Filgueira, Rosa; Krause, Amrey; Matser, Jonas; Casarotti, Emanuele; Magnoni, Federica; Gemund, Andre; Frobert, Laurent; Krischer, Lion; Atkinson, Malcolm

2015-04-01

The VERCE project is creating an e-Science platform to facilitate innovative data analysis and coding methods that fully exploit the wealth of data in global seismology. One of the technologies developed within the project is the Dispel4Py python library, which allows to describe abstract stream-based workflows for data-intensive applications and to execute them in a distributed environment. At runtime Dispel4Py is able to map workflow descriptions dynamically onto a number of computational resources (Apache Storm clusters, MPI powered clusters, and shared-memory multi-core machines, single-core machines), setting it apart from other workflow frameworks. Therefore, Dispel4Py enables scientists to focus on their computation instead of being distracted by details of the computing infrastructure they use. Among the workflows developed with Dispel4Py in VERCE, we mention here those for Seismic Ambient Noise Cross-Correlation and MISFIT calculation, which address two data-intensive problems that are common in computational seismology. The former, also called Passive Imaging, allows the detection of relative seismic-wave velocity variations during the time of recording, to be associated with the stress-field changes that occurred in the test area. The MISFIT instead, takes as input the synthetic seismograms generated from HPC simulations for a certain Earth model and earthquake and, after a preprocessing stage, compares them with real observations in order to foster subsequent model updates and improvement (Inversion). The VERCE Science Gateway exposes the MISFIT calculation workflow as a service, in combination with the simulation phase. Both phases can be configured, controlled and monitored by the user via a rich user interface which is integrated within the gUSE Science Gateway framework, hiding the complexity of accessing third parties data services, security mechanisms and enactment on the target resources. Thanks to a modular extension to the Dispel4Py framework

Digital Dilemma: Intellectual Property [and] The ERCIM Technical Reference Digital Library [and] International Information Gateway Collaboration [and] The Standards Fora for Online Education.

ERIC Educational Resources Information Center

Gladney, Henry M.; Andreoni, Antonella; Baldacci, Maria Bruna; Biagioni, Stefania; Carlesi, Carlo; Castelli, Donatella; Pagano, Pasquale; Peters, Carol; Pisani, Serena; Dempsey, Lorcan; Gardner, Tracy; Day, Michael; van der Werf, Titia; Bacsich, Paul; Heath, Andy; Lefrere, Paul; Miller, Paul; Riley, Kevin

1999-01-01

Includes four articles that discuss the impact of the emerging digital information infrastructure on intellectual property; the implementation of a digital library for a European consortium of national research institutions; an international information gateway collaboration; and developing standards for the description and sharing of educational…

Data Leakage Prevention: E-Mail Protection via Gateway

NASA Astrophysics Data System (ADS)

Kaur, Kamaljeet; Gupta, Ishu; Singh, Ashutosh Kumar

2018-01-01

Protection of digital assets and intellectual property is becoming a challenge for most of the companies. Due to increasing availability of database services on internet, data may be insecure after passing through precarious networks. To protect intellectual property (IP) is a major concern for today's organizations, because a leakage that compromises IP means, sensitive information of a company is in the hands of biggest competitors. Electronic information processing and communication is replacing paper in many applications increasingly. Instead of paper, an email is being used for communication at workplace and from social media logins to bank accounts. Nowadays an email is becoming a mainstream business tool. An email can be misused to leave company’s sensitive data open to compromise. So, it may be of little surprise that attacks on emails are common. So, here we need an email protection system (EPS) that will protect information to leave organization via mail. In this paper, we developed an algorithm that will offer email protection via gateway during data transfer. This algorithm matches the patterns with the keywords stored in the database and then takes the actions accordingly to protect the data. This paper describes why email protection is important? How companies can protect their confidential information from being leaked by insiders.

Integration of communications with the Intelligent Gateway Processor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hampel, V.E.

1986-01-01

The Intelligent Gateway Processor (IGP) software is being used to interconnect users equipped with different personal computers and ASCII terminals to mainframe machines of different make. This integration is made possible by the IGP's unique user interface and networking software. Prototype systems of the table-driven, interpreter-based IGP have been adapted to very different programmatic requirements and have demonstrated substantial increases in end-user productivity. Procedures previously requiring days can now be carried out in minutes. The IGP software has been under development by the Technology Information Systems (TIS) program at Lawrence Livermore National Laboratory (LLNL) since 1975 and is in usemore » by several federal agencies since 1983: The Air Force is prototyping applications which range from automated identification of spare parts for aircraft to office automation and the controlled storage and distribution of technical orders and engineering drawings. Other applications of the IGP are the Information Management System (IMS) for aviation statistics in the Federal Aviation Administration (FAA), the Nuclear Criticality Information System (NCIS) and a nationwide Cost Estimating System (CES) in the Department of Energy, the library automation network of the Defense Technical Information Center (DTIC), and the modernization program in the Office of the Secretary of Defense (OSD). 31 refs., 9 figs.« less

Geology of the Gateway quadrangle, Mesa county Colorado

USGS Publications Warehouse

Cater, Fred W.

1953-01-01

The Gateway quadrangle is one of eighteen 7 1/2-minute quadrangles covering the principal carnotite-producing area of southwestern Colorado. The geology of these quadrangles was mapped by the U.S. Geological Survey for the Atomic Energy Commission as part of a comprehensive study of carnotite deposits. The rocks exposed in the eighteen quadrangles consist of crystalline rocks of pre-Cambrian age and sedimentary rocks that range in age from late Paleozoic to Quaternary. Over much of the area the sedimentary rocks are flat lying, but in places the rocks are disrupted by hih-angle faults, and northwest-trending folds. Conspicuous among the folds are large anticlines having cores of intrusive salt and gypsum. Most of the carnotite deposits are confined to the Salt Wash sandstone member of Jurassic Morrison formation. Within this sandstone, most of the deposits are spottily distributed through an arcuate zone known as "Uruvan Mineral Belt". Individual deposits range in size from irregular masses containing only a few tons of ore to large, tabular masses containing many thousands of tons. The ore consists largely of sandstone selectively impregnated and in part replaced by uranium and vanadium minerals. Most of the deposits appear to be related to certain sedimentary structures in sandstones of favorable composition.

Mental health service utilization of Somali adolescents: religion, community, and school as gateways to healing.

PubMed

Ellis, B Heidi; Lincoln, Alisa K; Charney, Meredith E; Ford-Paz, Rebecca; Benson, Molly; Strunin, Lee

2010-11-01

This mixed-method study examines the utility of the Gateway Provider Model (GPM) in understanding service utilization and pathways to help for Somali refugee adolescents. Somali adolescents living in the Northeastern United States, and their caregivers, were interviewed. Results revealed low rates of use of mental health services. However other sources of help, such as religious and school personnel, were accessed more frequently. The GPM provides a helpful model for understanding refugee youth access to services, and an elaborated model is presented showing how existing pathways to help could be built upon to improve refugee youth access to services.

Design of an Open Smart Energy Gateway for Smart Meter Data Management

DOE Office of Scientific and Technical Information (OSTI.GOV)

Page, Janie; McParland, Chuck; Piette, Mary Ann

With the widespread deployment of electronic interval meters, commonly known as smart meters, came the promise of real-time data on electric energy consumption. Recognizing an opportunity to provide consumers access to their near real-time energy consumption data directly from their installed smart meter, we designed a mechanism for capturing those data for consumer use via an open smart energy gateway (OpenSEG). By design, OpenSEG provides a clearly defined boundary for equipment and data ownership. OpenSEG is an open-source data management platform to enable better data management of smart meter data. Effectively, it is an information architecture designed to work withmore » the ZigBee Smart Energy Profile 1.x (SEP 1.x). It was specifically designed to reduce cyber-security risks and provide secure information directly from smart meters to consumers in near real time, using display devices already owned by the consumers. OpenSEG stores 48 hours of recent consumption data in a circular cache using a format consistent with commonly available archived (not real-time) consumption data such as Green Button, which is based on the Energy Services Provider Interface (ESPI) data standard. It consists of a common XML format for energy usage information and a data exchange protocol to facilitate automated data transfer upon utility customer authorization. Included in the design is an application program interface by which users can acquire data from OpenSEG for further post processing. A sample data display application is included in the initial software product. The data display application demonstrates that OpenSEG can help electricity use data to be retrieved from a smart meter and ported to a wide variety of user-owned devices such as cell phones or a user-selected database. This system can be used for homes, multi-family buildings, or small commercial buildings in California.« less

Public Hearing and Comment Period Documents for the Northeast Gateway Energy Bridge Deepwater, Federal Waters of Massachusetts Bay (Modification to Existing Permit LNG Regasification Vessel/DWP Project)

EPA Pesticide Factsheets

List of public hearing & comment period document(s) for the Northeast Gateway Energy Bridge Deepwater Port, Federal Waters of Massachusetts Bay (Modification to Existing Permit LNG Regasification Vessel/DWP Project).

The Deep Space Gateway Lightning Mapper (DLM) — Monitoring Global Change and Thunderstorm Processes through Observations of Earth's High-Latitude Lightning from Cis-Lunar Orbit

NASA Astrophysics Data System (ADS)

Lang, T. J.; Blakeslee, R. J.; Cecil, D. J.; Christian, H. J.; Gatlin, P. N.; Goodman, S. J.; Koshak, W. J.; Petersen, W. A.; Quick, M.; Schultz, C. J.; Tatum, P. F.

2018-02-01

We propose the Deep Space Gateway Lightning Mapper (DLM) instrument. The primary goal of the DLM is to optically monitor Earth's high-latitude (50° and poleward) total lightning not observed by current and planned spaceborne lightning mappers.

Mathematics and online learning experiences: a gateway site for engineering students

NASA Astrophysics Data System (ADS)

Masouros, Spyridon D.; Alpay, Esat

2010-03-01

This paper focuses on the preliminary design of a multifaceted computer-based mathematics resource for undergraduate and pre-entry engineering students. Online maths resources, while attractive in their flexibility of delivery, have seen variable interest from students and teachers alike. Through student surveys and wide consultations, guidelines have been developed for effectively collating and integrating learning, support, application and diagnostic tools to produce an Engineer's Mathematics Gateway. Specific recommendations include: the development of a shared database of engineering discipline-specific problems and examples; the identification of, and resource development for, troublesome mathematics topics which encompass ideas of threshold concepts and mastery components; the use of motivational and promotional material to raise student interest in learning mathematics in an engineering context; the use of general and lecture-specific concept maps and matrices to identify the needs and relevance of mathematics to engineering topics; and further exploration of the facilitation of peer-based learning through online resources.

Enhancing the MeSH thesaurus to retrieve French online health resources in a quality-controlled gateway.

PubMed

Douyère, Magaly; Soualmia, Lina F; Névéol, Aurélie; Rogozan, Alexandrina; Dahamna, Badisse; Leroy, Jean-Philippe; Thirion, Benoît; Darmoni, Stefan J

2004-12-01

The amount of health information available on the Internet is considerable. In this context, several health gateways have been developed. Among them, CISMeF (Catalogue and Index of Health Resources in French) was designed to catalogue and index health resources in French. The goal of this article is to describe the various enhancements to the MeSH thesaurus developed by the CISMeF team to adapt this terminology to the broader field of health Internet resources instead of scientific articles for the medline bibliographic database. CISMeF uses two standard tools for organizing information: the MeSH thesaurus and several metadata element sets, in particular the Dublin Core metadata format. The heterogeneity of Internet health resources led the CISMeF team to enhance the MeSH thesaurus with the introduction of two new concepts, respectively, resource types and metaterms. CISMeF resource types are a generalization of the publication types of medline. A resource type describes the nature of the resource and MeSH keyword/qualifier pairs describe the subject of the resource. A metaterm is generally a medical specialty or a biological science, which has semantic links with one or more MeSH keywords, qualifiers and resource types. The CISMeF terminology is exploited for several tasks: resource indexing performed manually, resource categorization performed automatically, visualization and navigation through the concept hierarchies and information retrieval using the Doc'CISMeF search engine. The CISMeF health gateway uses several MeSH thesaurus enhancements to optimize information retrieval, hierarchy navigation and automatic indexing.

STEM Education as a Gateway to Future Astronomy: the Case of Ethiopian Universities

NASA Astrophysics Data System (ADS)

Adhana Teklr, Kelali

2015-08-01

Over last two decades education sector in Ethiopia has got due attention. To meet the education deficit of the nation number of universities has been increased from two to thirty eight and twelve more are coming soon. The proliferation has brought a spillover effect that universities have to compete for center excellence in research and education. Convincingly, government’s support is geared towards knowledge-based and innovation-driven system of education to back up the green economic development plan.In an effort to build inclusive economic development emphasis is given to innovative competency building through science and technology fields. The universities in the nation have establish laboratories to educate school boys and girls at early stage of their schooling in STEM (Science, Technology, Engineering and Mathematics) subjects as means to paving future destiny. Though most of the astronomy and space science labs are virtual ones; more and more student have been inspired and want astronomy and space science as their future career fields. Assessment study carried out in universities running STEM education showed that there is a mismatch between the capacity of the labs and number of students wanted to study astronomy and space sciences. The universities have endorsed that STEM education is the gateway to future astronomy and strongly advised concerned bodies and partnering institutions to collaboratively work to intensify the teaching-learning of STEM subjects.The assessment study compiled astronomic and space science exercises carried out by instructors and students and the document is ready to be disseminated to universities and middle and secondary schools to promote the science nationwide. The results have motivated university instructors, science and technology professionals, researchers and policy makers to be more involved in shaping future destiny of the young generation and have their shown determination to support the STEM education so that it will

Gateways to clinical trials.

PubMed

Bayés, M; Rabasseda, X; Prous, J R

2006-10-01

Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issues focuses on the following selection of drugs: (-)-Epigallocatechin gallate, (-)-gossypol, 2-deoxyglucose, 3,4-DAP, 7-monohydroxyethylrutoside; Ad5CMV-p53, adalimumab, adefovir dipivoxil, ADH-1, alemtuzumab, aliskiren fumarate, alvocidib hydrochloride, aminolevulinic acid hydrochloride, aminolevulinic acid methyl ester, amrubicin hydrochloride, AN-152, anakinra, anecortave acetate, antiasthma herbal medicine intervention, AP-12009, AP-23573, apaziquone, aprinocarsen sodium, AR-C126532, AR-H065522, aripiprazole, armodafinil, arzoxifene hydrochloride, atazanavir sulfate, atilmotin, atomoxetine hydrochloride, atorvastatin, avanafil, azimilide hydrochloride; Bevacizumab, biphasic insulin aspart, BMS-214662, BN-83495, bortezomib, bosentan, botulinum toxin type B; Caspofungin acetate, cetuximab, chrysin, ciclesonide, clevudine, clofarabine, clopidogrel, CNF-1010, CNTO-328, CP-751871, CX-717, Cypher; Dapoxetine hydrochloride, darifenacin hydrobromide, dasatinib, deferasirox, dextofisopam, dextromethorphan/quinidine sulfate, diclofenac, dronedarone hydrochloride, drotrecogin alfa (activated), duloxetine hydrochloride, dutasteride; Edaravone, efaproxiral sodium, emtricitabine, entecavir, eplerenone, epratuzumab, erlotinib hydrochloride, escitalopram oxalate, etoricoxib, ezetimibe, ezetimibe/simvastatin; Finrozole, fipamezole hydrochloride, fondaparinux sodium, fulvestrant; Gabapentin enacarbil, gaboxadol, gefitinib, gestodene, ghrelin (human); Human insulin, human papillomavirus vaccine; Imatinib mesylate, immunoglobulin intravenous (human), indiplon, insulin detemir, insulin glargine, insulin glulisine, intranasal insulin, istradefylline, i.v. gamma

Gateways to clinical trials.

PubMed

Bayes, M; Rabasseda, X; Prous, J R

2005-01-01

Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: (-)-Epigallocatechin gallate; ACP-103, Ad.Egr.TNF.11 D, adalimumab, AF-IL 12, AIDSVAX gp120 B/B, alefacept, alemtuzumab, a-Galactosylceramide, ALVAC vCP 1452, alvimopan hydrate, alvocidib hydrochloride, aminolevulinic acid hydrochloride, aminolevulinic acid methyl ester, anakinra, anidulafungin, antarelix, aprepitant, aripiprazole, arsenic sulfide, asoprisnil, atazanavir sulfate, atomoxetine hydrochloride; Bevacizumab, bimatoprost, BMS-184476, bortezomib, bosentan, botulinum toxin type B, BrachySil, brivudine; Caffeine, calcipotriol/betamethasone dipropionate, cannabidiol, capsaicin for injection, caspofungin acetate, CC-4047, cetuximab, CGP-36742, clofazimine, CpG-7909, Cypher; Darbepoetin alfa, dextromethorphan/quinidine sulfate, dimethylfumarate, dronabinol/cannabidiol, drotrecogin alfa (activated), duloxetine hydrochloride, dutasteride; Ecogramostim, efalizumab, eletriptan, emtricitabine, enfuvirtide, eplerenone, esomeprazole magnesium, estradiol acetate, eszopiclone, etoricoxib, exenatide, ezetimibe, ezetimibe/simvastatin; Fampridine, fondaparinux sodium, fosamprenavir calcium; Gefitinib, GPI-0100; hA 20, HTU-PA, human insulin, HuOKT 3 gamma 1(Ala 234-Ala 235), hyaluronic acid; Icatibant, imatinib mesylate, Indiplon, INKP-100, INKP-102, iodine (I131) tositumomab, istradefylline, IV gamma-globulin, ivabradine hydrochloride, ixabepilone; Lacosamide, landiolol, lanthanum carbonate, lasofoxifene tartrate, LB-80380, lenalidomide, lidocaine/tetracaine, linezolid, liposomal doxorubicin, liposomal vincristine sulfate, lopinavir, lopinavir/ritonavir, lumiracoxib, lurtotecan; Maribavir, morphine glucuronide, MVA-5 T

Mapping of medical acronyms and initialisms to Medical Subject Headings (MeSH) across selected systems

PubMed Central

Shultz, Mary

2006-01-01

Introduction: Given the common use of acronyms and initialisms in the health sciences, searchers may be entering these abbreviated terms rather than full phrases when searching online systems. The purpose of this study is to evaluate how various MEDLINE Medical Subject Headings (MeSH) interfaces map acronyms and initialisms to the MeSH vocabulary. Methods: The interfaces used in this study were: the PubMed MeSH database, the PubMed Automatic Term Mapping feature, the NLM Gateway Term Finder, and Ovid MEDLINE. Acronyms and initialisms were randomly selected from 2 print sources. The test data set included 415 randomly selected acronyms and initialisms whose related meanings were found to be MeSH terms. Each acronym and initialism was entered into each MEDLINE MeSH interface to determine if it mapped to the corresponding MeSH term. Separately, 46 commonly used acronyms and initialisms were tested. Results: While performance differed widely, the success rates were low across all interfaces for the randomly selected terms. The common acronyms and initialisms tested at higher success rates across the interfaces, but the differences between the interfaces remained. Conclusion: Online interfaces do not always map medical acronyms and initialisms to their corresponding MeSH phrases. This may lead to inaccurate results and missed information if acronyms and initialisms are used in search strategies. PMID:17082832

GATEWAY Demonstrations: Tuning Hospital Lighting: Evaluating Tunable LED Lighting at the Swedish Hospital Behavioral Health Unit in Seattle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilkerson, Andrea; Davis, Robert G.; Clark, Edward

The GATEWAY program evaluated a tunable LED lighting system installed in the new Swedish Medical Behavioral Health Unit in Seattle that incorporates color-tunable luminaires in common areas, and uses advanced controls for dimming and color tuning, with the goal of providing a better environment for staff and patients. The report reviews the design of the tunable lighting system, summarizes two sets of measurements, and discusses the circadian, energy, and commissioning implications as well as lessons learned from the project.

GATEWAY Demonstrations: Tuning the Light in Senior Care: Evaluating a Trial LED Lighting System at the ACC Care Center in Sacramento, CA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, Robert G.; Wilkerson, Andrea M.; Samla, Connie

The GATEWAY program documented the performance of tunable-white LED lighting systems installed in several spaces within the ACC Care Center, a senior-care facility in Sacramento, CA. The project results included energy savings and improved lighting quality, as well as other possible health-related benefits that may have been attributable, at least in part, to the lighting changes.

An Extensible Model and Analysis Framework

DTIC Science & Technology

2010-11-01

Eclipse or Netbeans Rich Client Platform (RCP). We call this the Triquetrum Project. Configuration files support narrower variability than Triquetrum/RCP...Triquetrum/RCP supports assembling in arbitrary ways. (12/08 presentation) 2. Prototyped OSGi component architecture for use with Netbeans and

Integrating the ODI-PPA scientific gateway with the QuickReduce pipeline for on-demand processing

NASA Astrophysics Data System (ADS)

Young, Michael D.; Kotulla, Ralf; Gopu, Arvind; Liu, Wilson

2014-07-01

As imaging systems improve, the size of astronomical data has continued to grow, making the transfer and processing of data a significant burden. To solve this problem for the WIYN Observatory One Degree Imager (ODI), we developed the ODI-Portal, Pipeline, and Archive (ODI-PPA) science gateway, integrating the data archive, data reduction pipelines, and a user portal. In this paper, we discuss the integration of the QuickReduce (QR) pipeline into PPA's Tier 2 processing framework. QR is a set of parallelized, stand-alone Python routines accessible to all users, and operators who can create master calibration products and produce standardized calibrated data, with a short turn-around time. Upon completion, the data are ingested into the archive and portal, and made available to authorized users. Quality metrics and diagnostic plots are generated and presented via the portal for operator approval and user perusal. Additionally, users can tailor the calibration process to their specific science objective(s) by selecting custom datasets, applying preferred master calibrations or generating their own, and selecting pipeline options. Submission of a QuickReduce job initiates data staging, pipeline execution, and ingestion of output data products all while allowing the user to monitor the process status, and to download or further process/analyze the output within the portal. User-generated data products are placed into a private user-space within the portal. ODI-PPA leverages cyberinfrastructure at Indiana University including the Big Red II supercomputer, the Scholarly Data Archive tape system and the Data Capacitor shared file system.

GATEWAY Report: Tuning the Light in Classrooms: Evaluating Trial LED Lighting Systems in Three Classrooms at the Carrollton-Farmers Branch Independent School District in Carrollton, TX

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, Robert G.; Wilkerson, Andrea

The GATEWAY program evaluated a trial installation of tunable-white LED lighting systems in three classrooms in the Carrollton-Farmers Branch Independent School District in Carrollton, TX. The report provides valuable insights into the use of this technology in a real-world setting.

A rapid and cost-effective method for sequencing pooled cDNA clones by using a combination of transposon insertion and Gateway technology.

PubMed

Morozumi, Takeya; Toki, Daisuke; Eguchi-Ogawa, Tomoko; Uenishi, Hirohide

2011-09-01

Large-scale cDNA-sequencing projects require an efficient strategy for mass sequencing. Here we describe a method for sequencing pooled cDNA clones using a combination of transposon insertion and Gateway technology. Our method reduces the number of shotgun clones that are unsuitable for reconstruction of cDNA sequences, and has the advantage of reducing the total costs of the sequencing project.

Acoustic detections of summer and winter whales at Arctic gateways in the Atlantic and Pacific Oceans

NASA Astrophysics Data System (ADS)

Stafford, K.; Laidre, K. L.; Moore, S. E.

2016-02-01

Changes in sea ice phenology have been profound in regions north of arctic gateways, where the seasonal open-water period has increased by 1.5-3 months over the past 30 years. This has resulted in changes to the Arctic ecosystem, including increased primary productivity, changing food web structure, and opening of new habitat. In the "new normal" Arctic, ice obligate species such as ice seals and polar bears may fare poorly under reduced sea ice while sub-arctic "summer" whales (fin and humpback) are poised to inhabit new seasonal ice-free habitats in the Arctic. We examined the spatial and seasonal occurrence of summer and "winter" (bowhead) whales from September through December by deploying hydrophones in three Arctic gateways: Bering, Davis and Fram Straits. Acoustic occurrence of the three species was compared with decadal-scale changes in seasonal sea ice. In all three Straits, fin whale acoustic detections extended from summer to late autumn. Humpback whales showed the same pattern in Bering and Davis Straits, singing into November and December, respectively. Bowhead whale detections generally began after the departure of the summer whales and continued through the winter. In all three straits, summer whales occurred in seasons and regions that used to be ice-covered. This is likely due to both increased available habitat from sea ice reductions and post-whaling population recoveries. At present, in the straits examined here, there is spatial, but not temporal, overlap between summer and winter whales. In a future with further seasonal sea ice reductions, however, increased competition for resources between sub-Arctic and Arctic species may arise to the detriment of winter whales.

A gateway system in rostral PFC? Evidence from biasing attention to perceptual information and internal representations.

PubMed

Henseler, Ilona; Krüger, Sebastian; Dechent, Peter; Gruber, Oliver

2011-06-01

Some situations require us to be highly sensitive to information in the environment, whereas in other situations, our attention is mainly focused on internally represented information. It has been hypothesized that a control system located in the rostral prefrontal cortex (PFC) acts as gateway between these two forms of attention. Here, we examined the neural underpinnings of this 'gateway system' using fMRI and functional connectivity analysis. We designed different tasks, in which the demands for attending to external or internal information were manipulated, and tested 1) whether there is a functional specialization within the rostral PFC along a medial-lateral dimension, and 2) whether these subregions can influence attentional weighting processes by specifically interacting with other parts of the brain. Our results show that lateral aspects of the rostral PFC are preferentially activated when attention is directed to internal representations, whereas anterior medial aspects are activated when attention is directed to sensory events. Furthermore, the rostrolateral subregion was preferentially connected to regions in the prefrontal and parietal cortex during internal attending, whereas the rostromedial subregion was connected to the basal ganglia, thalamus, and sensory association cortices during external attending. Finally, both subregions interacted with another important prefrontal region involved in cognitive control, the inferior frontal junction, in a task-specific manner, depending on the current attentional demands. These findings suggest that the rostrolateral and rostromedial part of the anterior PFC have dissociable roles in attentional control, and that they might, as part of larger networks, be involved in dynamically adjusting the contribution of internal and external information to current cognition. Copyright © 2011 Elsevier Inc. All rights reserved.

Direct Characterization of Comets and Asteroids via Cosmic Dust Analysis from the Deep Space Gateway

NASA Technical Reports Server (NTRS)

Fries, M.; Fisher, K.

2018-01-01

The Deep Space Gateway (DSG) may provide a platform for direct sampling of a large number of comets and asteroids, through employment of an instrument for characterizing dust from these bodies. Every year, the Earth traverses through debris streams of dust and small particles from comets and asteroids in Earth-crossing orbits, generating short-lived outbursts of meteor activity commonly known as "meteor showers" (Figure 1). The material in each debris stream originates from a distinct parent body, many of which have been identified. By sampling this material, it is possible to quantitatively analyze the composition of a dozen or more comets and asteroids (See Figure 2, following page) without leaving cislunar space.

Towards the impact of eddies on the response of the global ocean circulation to Southern Ocean gateway opening

NASA Astrophysics Data System (ADS)

Viebahn, Jan; von der Heydt, Anna S.; Dijkstra, Henk A.

2014-05-01

During the past 65 Million (Ma) years, Earth's climate has undergone a major change from warm 'greenhouse' to colder 'icehouse' conditions with extensive ice sheets in the polar regions of both hemispheres. The Eocene-Oligocene (~34 Ma) and Oligocene-Miocene (~23 Ma) boundaries reflect major transitions in Cenozoic global climate change. Proposed mechanisms of these transitions include reorganization of ocean circulation due to critical gateway opening/deepening, changes in atmospheric CO2-concentration, and feedback mechanisms related to land-ice formation. A long-standing hypothesis is that the formation of the Antarctic Circumpolar Current due to opening/deepening of Southern Ocean gateways led to glaciation of the Antarctic continent. However, while this hypothesis remains controversial, its assessment via coupled climate model simulations depends crucially on the spatial resolution in the ocean component. More precisely, only high-resolution modeling of the turbulent ocean circulation is capable of adequately describing reorganizations in the ocean flow field and related changes in turbulent heat transport. In this study, for the first time results of a high-resolution (0.1° horizontally) realistic global ocean model simulation with a closed Drake Passage are presented. Changes in global ocean temperatures, heat transport, and ocean circulation (e.g., Meridional Overturning Circulation and Antarctic Coastal Current) are established by comparison with an open Drake Passage high-resolution reference simulation. Finally, corresponding low-resolution simulations are also analyzed. The results highlight the essential impact of the ocean eddy field in palaeoclimatic change.

Late Cretaceous climate simulations with different CO2 levels and subarctic gateway configurations: A model-data comparison

NASA Astrophysics Data System (ADS)

Niezgodzki, Igor; Knorr, Gregor; Lohmann, Gerrit; Tyszka, Jarosław; Markwick, Paul J.

2017-09-01

We investigate the impact of different CO2 levels and different subarctic gateway configurations on the surface temperatures during the latest Cretaceous using the Earth System Model COSMOS. The simulated temperatures are compared with the surface temperature reconstructions based on a recent compilation of the latest Cretaceous proxies. In our numerical experiments, the CO2 level ranges from 1 to 6 times the preindustrial (PI) CO2 level of 280 ppm. On a global scale, the most reasonable match between modeling and proxy data is obtained for the experiments with 3 to 5 × PI CO2 concentrations. However, the simulated low- (high-) latitude temperatures are too high (low) as compared to the proxy data. The moderate CO2 levels scenarios might be more realistic, if we take into account proxy data and the dead zone effect criterion. Furthermore, we test if the model-data discrepancies can be caused by too simplistic proxy-data interpretations. This is distinctly seen at high latitudes, where most proxies are biased toward summer temperatures. Additional sensitivity experiments with different ocean gateway configurations and constant CO2 level indicate only minor surface temperatures changes (< 1°C) on a global scale, with higher values (up to 8°C) on a regional scale. These findings imply that modeled and reconstructed temperature gradients are to a large degree only qualitatively comparable, providing challenges for the interpretation of proxy data and/or model sensitivity. With respect to the latter, our results suggest that an assessment of greenhouse worlds is best constrained by temperatures in the midlatitudes.

The social exigencies of the gateway progression to the use of illicit drugs from adolescence into adulthood.

PubMed

Otten, Roy; Mun, Chung Jung; Dishion, Thomas J

2017-10-01

There is limited empirical integration between peer clustering theory and the Gateway framework. The goal of the present study was to test the hypothesis that friendship associations partly predict gateway escalations in the use of drugs from adolescence to adulthood. This longitudinal study analyzed 3 waves of data from a community sample of 711 male and female participants without a history of illicit drug use reporting drug use at age 17, 22, and 27. Substance use assessments including tobacco, alcohol, cannabis, onset and abuse/dependence tendency of illicit drugs other than cannabis (i.e., cocaine, methamphetamine, and opiates), and friends' reported use of illicit drugs. Structural equation modeling was used to test the hypothesized model. Participants' cannabis use level at age 17 was positively associated with perceived friends' drug use at age 22, which in turn predicted participants' onset of illicit drug use between ages 22 and 27. Moreover, progression of tobacco use throughout age 17 to 22 was associated with an increased onset of illicit drug use between ages 22 and 27. Apart for an effect of cannabis use at age 22 on abuse and dependence tendency to various drugs at age 28, results were similar. During this period of development, the availability and selection of drug-using friends contributes to the progression to potentially more rewarding and damaging illicit drugs. These findings suggest the need to attend to the peer ecology in prevention and support the common practice of using abstaining peers in treatment for drug dependence. Copyright © 2017. Published by Elsevier Ltd.

The Eocene-Oligocene transition in the North Alpine Foreland Basin and subsequent closure of a Paratethys gateway

NASA Astrophysics Data System (ADS)

van der Boon, A.; Beniest, A.; Ciurej, A.; Gaździcka, E.; Grothe, A.; Sachsenhofer, R. F.; Langereis, C. G.; Krijgsman, W.

2018-03-01

During the Eocene-Oligocene transition (EOT), a major palaeoenvironmental change took place in the Paratethys Sea of central Eurasia. Restricted connectivity and increased stratification resulted in wide-spread deposition of organic-rich sediments which nowadays make up important hydrocarbon source rocks. The North Alpine Foreland Basin (NAFB) was a major gateway of the Paratethys Sea to the open ocean during the Eocene, but the age of closure of this gateway is still uncertain. The Ammer section in southern Germany documents the shallowing of this connection and subsequent disappearance of marine environments in the NAFB, as reflected in its sedimentary succession of turbidites to marls (Deutenhausen to Tonmergel beds), via coastal sediments (Baustein beds) to continental conglomerates (Weißach beds). Here, we apply organic geochemistry and date the lithological transitions in the Ammer section using integrated stratigraphy, including magnetostratigraphy and biostratigraphy. Nannoplankton and dinocyst results can be reconciled when dinoflagellate species Wetzeliella symmetrica is of late Eocene age. Our magnetostratigraphy then records C13r-C13n-C12r and allows calculation of sediment accumulation rates and estimation of ages of lithological transitions. We show that the shallowing from turbiditic slope deposits (Deutenhausen beds) to shelf sediments (Tonmergel beds) coincides with the Eocene-Oligocene boundary at 33.9 Ma. The transition to continental sediments is dated at ca. 33.15 Ma, significantly older than suggested by previous studies. We conclude that the transition from marine to continental sediments drastically reduced the marine connection through the western part of the NAFB and influenced the oxygen conditions of the Paratethys Sea.

Cultural models of self and social class disparities at organizational gateways and pathways.

PubMed

Townsend, Sarah Sm; Truong, Mindy

2017-12-01

Attaining a college degree has traditionally been assumed to be key to upward social and professional mobility. However, college graduates from working-class backgrounds achieve less career success in professional, white-collar workplaces compared to those from middle-class backgrounds. Using a cultural models approach, we examine how the independent cultural beliefs and practices promoted by professional organizations disadvantage people from working-class backgrounds, who espouse interdependent beliefs and practices. Our review illustrates how this disadvantage can manifest in two ways. First, despite relative equality in objective qualifications, it can occur at organizational gateways (e.g., interview and hiring decisions). Second, even after people from working-class backgrounds gain access to an organization, it can occur along organizational pathways (e.g., performance evaluations and assignment to high-profile tasks). Copyright © 2017. Published by Elsevier Ltd.

Supporting Ecological Research With a Flexible Satellite Sensornet Gateway

NASA Astrophysics Data System (ADS)

Silva, F.; Rundel, P. W.; Graham, E. A.; Falk, A.; Ye, W.; Pradkin, Y.; Deschon, A.; Bhatt, S.; McHenry, T.

2007-12-01

Wireless sensor networks are a promising technology for ecological research due to their capability to make continuous and in-situ measurements. However, there are some challenges for the wide adoption of this technology by scientists, who may have various research focuses. First, the observation system needs to be rapidly and easily deployable at different remote locations. Second, the system needs to be flexible enough to meet the requirements of different applications and easily reconfigurable by scientists, who may not always be technology experts. To address these challenges, we designed and implemented a flexible satellite gateway for using sensor networks. Our first prototype is being deployed at Stunt Ranch in the Santa Monica Mountains to support biological research at UCLA. In this joint USC/ISI-UCLA deployment, scientists are interested in a long-term investigation of the influence of the 2006-07 southern California drought conditions on the water relations of important chaparral shrub and tree species that differ in their depth of rooting. Rainfall over this past hydrologic year in southern California has been less than 25% of normal, making it the driest year on record. In addition to core measurements of air temperature, relative humidity, wind speed, solar irradiance, rainfall, and soil moisture, we use constant-heating sap flow sensors to continuously monitor the flow of water through the xylem of replicated stems of four species to compare their access to soil moisture with plant water stress. Our gateway consists of a front-end data acquisition system and a back-end data storage system, connected by a long-haul satellite communication link. At the front-end, all environmental sensors are connected to a Compact RIO, a rugged data acquisition platform developed by National Instruments. Sap flow sensors are deployed in several locations that are 20 to 50 meters away from the Compact RIO. At each plant, a Hobo datalogger is used to collect sap flow

A Split-GFP Gateway Cloning System for Topology Analyses of Membrane Proteins in Plants.

PubMed

Xie, Wenjun; Nielsen, Mads Eggert; Pedersen, Carsten; Thordal-Christensen, Hans

2017-01-01

To understand the function of membrane proteins, it is imperative to know their topology. For such studies, a split green fluorescent protein (GFP) method is useful. GFP is barrel-shaped, consisting of 11 β-sheets. When the first ten β-sheets (GFP1-10) and the 11th β-sheet (GFP11) are expressed from separate genes they will self-assembly and reconstitute a fluorescent GFP protein. However, this will only occur when the two domains co-localize in the same cellular compartment. We have developed an easy-to-use Gateway vector set for determining on which side of the membrane the N- and C-termini are located. Two vectors were designed for making N- and C-terminal fusions between the membrane proteins-of-interest and GFP11, while another three plasmids were designed to express GFP1-10 in either the cytosol, the endoplasmic reticulum (ER) lumen or the apoplast. We tested functionality of the system by applying the vector set for the transmembrane domain, CNXTM, of the ER membrane protein, calnexin, after transient expression in Nicotiana benthamiana leaves. We observed GFP signal from the ER when we reciprocally co-expressed GFP11-CNXTM with GFP1-10-HDEL and CNXTM-GFP with cytosolic GFP1-10. The opposite combinations did not result in GFP signal emission. This test using the calnexin ER-membrane domain demonstrated its C-terminus to be in the cytosol and its N-terminus in the ER lumen. This result confirmed the known topology of calnexin, and we therefore consider this split-GFP system highly useful for ER membrane topology studies. Furthermore, the vector set provided is useful for detecting the topology of proteins on other membranes in the cell, which we confirmed for a plasma membrane syntaxin. The set of five Ti-plasmids are easily and efficiently used for Gateway cloning and transient transformation of N. benthamiana leaves.

Correlates of sexual initiation among European adolescents.

PubMed

Gambadauro, Pietro; Carli, Vladimir; Hadlaczky, Gergö; Sarchiapone, Marco; Apter, Alan; Balazs, Judit; Banzer, Raphaela; Bobes, Julio; Brunner, Romuald; Cosman, Doina; Farkas, Luca; Haring, Christian; Hoven, Christina W; Kaess, Michael; Kahn, Jean Pierre; McMahon, Elaine; Postuvan, Vita; Sisask, Merike; Värnik, Airi; Zadravec Sedivy, Nusa; Wasserman, Danuta

2018-01-01

Sexuality is a physiological component of adolescent development, though early initiation is associated with reproductive health risk. This study aimed at identifying correlates and predictors of sexual initiation in a large multinational cohort of European adolescents. A questionnaire addressing socio-demographics, behaviours, mental health and sexual activity, was delivered to 11,110 adolescents recruited from 168 randomly selected schools in 10 European countries between 2009 and 2011. A follow-up questionnaire was delivered after 12 months. The longitudinal association of baseline risk behaviors, psychological attributes and contextual vulnerabilities, with sexual initiation during follow-up was evaluated through simple and multivariable age/sex stratified logistic regression. Multinomial logistic regression measured the association between predictors and sexual initiation with or without coexisting reproductive risk factors, such as multiple partners or infrequent condom use. Baseline sexual experience was reported by 19.2% of 10,757 respondents (median age 15; IQR 14-15; females 59.6%). This was significantly more frequent among pupils older than 15 (41%) and males (20.8%). Of 7,111 pupils without previous experience who were available at follow-up (response rate 81.8%), 17% reported sexual initiation, without differences between females and males. Baseline smoking (age/sex adjusted odds ratio [aOR] 3.63), alcohol use (aOR 2.95), illegal drugs use (aOR 2.72), and poor sleep (aOR 1.71) predicted sexual initiation. Stratified analyses showed a particularly strong association in case of younger and female pupils, and, among girls, when initiation was reported together with multiple partners and/or infrequent condom use. Externalizing (i.e. conduct and hyperactivity) symptoms independently predicted sexual initiation. Internalizing difficulties (i.e. emotional and peer problems) were negatively associated with early and risky sexual initiation among boys

Structure and Evaluation of a Flipped General Chemistry Course as a Model for Small and Large Gateway Science Courses at an Urban Public Institution

ERIC Educational Resources Information Center

Deri, Melissa A.; Mills, Pamela; McGregor, Donna

2018-01-01

A flipped classroom is one where students are first introduced to content outside of the classroom. This frees up class time for more active learning strategies and has been shown to enhance student learning in high school and college classrooms. However, many studies in General Chemistry, a college gateway science course, were conducted in small…

The Gateway Paper--context and configuration of the proposed health reforms in Pakistan.

PubMed

Nishtar, Sania

2006-12-01

As an opening of a dialogue on health reforms in Pakistan, the Gateway Paper presents a viewpoint on its proposed directions making a strong case for systems reforms, which need to scope beyond the healthcare system. Positioning the reform process to strengthen Pakistan's health policy cycle, the paper articulates a roadmap for a paradigm shift to achieve health outcomes in Pakistan with major structural reorganization within the health system. The proposed reform points in the four areas namely, reforms within the health sector, overarching measures, reconfiguration of health within an inter-sectoral scope and generating evidence for reforms. Reforms within the health sector focus on developing new models of service delivery and health financing which can enable the state to leverage the private sector outreach to deliver health-related public goods on the one hand and maximize the outreach of the State's health care delivery mechanisms through mainstreaming the role of the private sector on the other, albeit with safeguards. In addition, these call for strengthening the stewardship role to regulate these arrangements. The second area of reform focuses on overarching measures; these include developing frameworks for public-private partnerships which will enable the bringing together of organizations with the mandate to offer public goods and those that could facilitate this goal through the provision of resources, technical expertise or outreach; mainstreaming health into the country's social protection strategy in order to address issues of access and affordability for the poor and introducing civil service and public service reform focused on good governance, accountability, breakdown of institutional corruption which are critical to improving health outcomes. The third area of reform involves broadening health to its inter-sectoral scope, redefinition of objectives and targets within the health sector and garnering support from across the sectors to forester

GATEWAY Report Brief: Tuning the Light in Classrooms: Evaluating Trial LED Lighting Systems in Three Classrooms at the Carrollton-Farmers Branch Independent School District in Carrollton, TX

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Summary of GATEWAY report evaluating a trial installation of tunable-white LED lighting systems in three classrooms in the Carrollton-Farmers Branch Independent School District in Carrollton, TX. The report provides valuable insights into the use of this technology in a real-world setting.

The Gateway Paper--preventive and promotive programs in Pakistan and health reforms in Pakistan.

PubMed

Nishtar, Sania

2006-12-01

Pakistan's public health interventions include a range of programs lead by the federal government with implementation arms at the provincial and district levels. Some of the programs are disease specific such as the respective programs on HIV/AIDS, Malaria, Tuberculosis, non-communicable diseases and Hepatitis; others are specific to life cycle domains such as in the case of maternal and child health whereas still others such as the National Program for Family Planning and Primary Healthcare and the National Expanded Program for Immunization are cross-cutting. Although these programs have contributed to improving health outcomes at intermediate outcomes level, a number of critical impediments to maximizing their impact have been noted. These include lack of integration, institutional impediments to the implementation of programs with particular reference to problems at the federal/provincial level and unrealized implications of federal programs at the provincial level are amongst the foremost. These have been further compounded by the addition of another service delivery tier in Pakistan's health system through the introduction of the devolution initiative. Furthermore, the unsustainable and under-utilized BHUs which serve as the service delivery base of these programs add to the problems. The Gateway Paper makes a number of recommendations to obviate these issues such as recommendations to integrate programs, strengthen surveillance systems, and with reference to obviating issues to implementation, emphasis is laid on decentralizing decision-making and central control, institutionalizing managerial audit, and prioritizing specific governance and management reforms. The Paper also stresses on the need for establishing a national coordination mechanism for fostering federal/provincial harmony and ensuring the creation of appropriate counterpart institutional arrangements in the provinces and districts. Recommendations on restructuring BHUs at a management, oversight

A Tol2 Gateway-Compatible Toolbox for the Study of the Nervous System and Neurodegenerative Disease.

PubMed

Don, Emily K; Formella, Isabel; Badrock, Andrew P; Hall, Thomas E; Morsch, Marco; Hortle, Elinor; Hogan, Alison; Chow, Sharron; Gwee, Serene S L; Stoddart, Jack J; Nicholson, Garth; Chung, Roger; Cole, Nicholas J

2017-02-01

Currently there is a lack in fundamental understanding of disease progression of most neurodegenerative diseases, and, therefore, treatments and preventative measures are limited. Consequently, there is a great need for adaptable, yet robust model systems to both investigate elementary disease mechanisms and discover effective therapeutics. We have generated a Tol2 Gateway-compatible toolbox to study neurodegenerative disorders in zebrafish, which includes promoters for astrocytes, microglia and motor neurons, multiple fluorophores, and compatibility for the introduction of genes of interest or disease-linked genes. This toolbox will advance the rapid and flexible generation of zebrafish models to discover the biology of the nervous system and the disease processes that lead to neurodegeneration.

76 FR 51462 - Notice of Release of an Easement Restriction at Phoenix-Mesa Gateway Airport, Mesa, AZ

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-18

...The Federal Aviation Administration (FAA) proposes to rule and invites public comment on the application for a release of a U.S. Air Force easement restriction covering 52.6 acres of property abutting Phoenix-Mesa Gateway, Mesa, Arizona, from all conditions contained in a grant of an easement, since the easement is not needed for civilian airport purposes. In exchange for the easement, the airport will receive 19 acres of land and a new avigation easement. Reuse of the land under the easement will remain compatible and not interfere with the airport or its operation. The interest of civil aviation is properly served by the release.

Understanding nuclear motions in molecules: Derivation of Eckart frame ro-vibrational Hamiltonian operators via a gateway Hamiltonian operator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Szalay, Viktor, E-mail: szalay.viktor@wigner.mta.hu

A new ro-vibrational Hamiltonian operator, named gateway Hamiltonian operator, with exact kinetic energy term, T-hat, is presented. It is in the Eckart frame and it is of the same form as Watson’s normal coordinate Hamiltonian. However, the vibrational coordinates employed are not normal coordinates. The new Hamiltonian is shown to provide easy access to Eckart frame ro-vibrational Hamiltonians with exact T-hat given in terms of any desired set of vibrational coordinates. A general expression of the Eckart frame ro-vibrational Hamiltonian operator is given and some of its properties are discussed.

Enabling Research without Geographical Boundaries via Collaborative Research Infrastructures

NASA Astrophysics Data System (ADS)

Gesing, S.

2016-12-01

Collaborative research infrastructures on global scale for earth and space sciences face a plethora of challenges from technical implementations to organizational aspects. Science gateways - also known as virtual research environments (VREs) or virtual laboratories - address part of such challenges by providing end-to-end solutions to aid researchers to focus on their specific research questions without the need to become acquainted with the technical details of the complex underlying infrastructures. In general, they provide a single point of entry to tools and data irrespective of organizational boundaries and thus make scientific discoveries easier and faster. The importance of science gateways has been recognized on national as well as on international level by funding bodies and by organizations. For example, the US NSF has just funded a Science Gateways Community Institute, which offers support, consultancy and open accessible software repositories for users and developers; Horizon 2020 provides funding for virtual research environments in Europe, which has led to projects such as VRE4EIC (A Europe-wide Interoperable Virtual Research Environment to Empower Multidisciplinary Research Communities and Accelerate Innovation and Collaboration); national or continental research infrastructures such as XSEDE in the USA, Nectar in Australia or EGI in Europe support the development and uptake of science gateways; the global initiatives International Coalition on Science Gateways, the RDA Virtual Research Environment Interest Group as well as the IEEE Technical Area on Science Gateways have been founded to provide global leadership on future directions for science gateways in general and facilitate awareness for science gateways. This presentation will give an overview on these projects and initiatives aiming at supporting domain researchers and developers with measures for the efficient creation of science gateways, for increasing their usability and sustainability

NASA's Earth Science Gateway: A Platform for Interoperable Services in Support of the GEOSS Architecture

NASA Astrophysics Data System (ADS)

Alameh, N.; Bambacus, M.; Cole, M.

2006-12-01

Nasa's Earth Science as well as interdisciplinary research and applications activities require access to earth observations, analytical models and specialized tools and services, from diverse distributed sources. Interoperability and open standards for geospatial data access and processing greatly facilitate such access among the information and processing compo¬nents related to space¬craft, airborne, and in situ sensors; predictive models; and decision support tools. To support this mission, NASA's Geosciences Interoperability Office (GIO) has been developing the Earth Science Gateway (ESG; online at http://esg.gsfc.nasa.gov) by adapting and deploying a standards-based commercial product. Thanks to extensive use of open standards, ESG can tap into a wide array of online data services, serve a variety of audiences and purposes, and adapt to technology and business changes. Most importantly, the use of open standards allow ESG to function as a platform within a larger context of distributed geoscience processing, such as the Global Earth Observing System of Systems (GEOSS). ESG shares the goals of GEOSS to ensure that observations and products shared by users will be accessible, comparable, and understandable by relying on common standards and adaptation to user needs. By maximizing interoperability, modularity, extensibility and scalability, ESG's architecture fully supports the stated goals of GEOSS. As such, ESG's role extends beyond that of a gateway to NASA science data to become a shared platform that can be leveraged by GEOSS via: A modular and extensible architecture Consensus and community-based standards (e.g. ISO and OGC standards) A variety of clients and visualization techniques, including WorldWind and Google Earth A variety of services (including catalogs) with standard interfaces Data integration and interoperability Mechanisms for user involvement and collaboration Mechanisms for supporting interdisciplinary and domain-specific applications ESG

The sources of atmospheric black carbon at a European gateway to the Arctic

NASA Astrophysics Data System (ADS)

Winiger, P.; Andersson, A.; Eckhardt, S.; Stohl, A.; Gustafsson, Ö.

2016-09-01

Black carbon (BC) aerosols from incomplete combustion of biomass and fossil fuel contribute to Arctic climate warming. Models--seeking to advise mitigation policy--are challenged in reproducing observations of seasonally varying BC concentrations in the Arctic air. Here we compare year-round observations of BC and its δ13C/Δ14C-diagnosed sources in Arctic Scandinavia, with tailored simulations from an atmospheric transport model. The model predictions for this European gateway to the Arctic are greatly improved when the emission inventory of anthropogenic sources is amended by satellite-derived estimates of BC emissions from fires. Both BC concentrations (R2=0.89, P<0.05) and source contributions (R2=0.77, P<0.05) are accurately mimicked and linked to predominantly European emissions. This improved model skill allows for more accurate assessment of sources and effects of BC in the Arctic, and a more credible scientific underpinning of policy efforts aimed at efficiently reducing BC emissions reaching the European Arctic.

The sources of atmospheric black carbon at a European gateway to the Arctic

PubMed Central

Winiger, P; Andersson, A; Eckhardt, S; Stohl, A; Gustafsson, Ö.

2016-01-01

Black carbon (BC) aerosols from incomplete combustion of biomass and fossil fuel contribute to Arctic climate warming. Models—seeking to advise mitigation policy—are challenged in reproducing observations of seasonally varying BC concentrations in the Arctic air. Here we compare year-round observations of BC and its δ13C/Δ14C-diagnosed sources in Arctic Scandinavia, with tailored simulations from an atmospheric transport model. The model predictions for this European gateway to the Arctic are greatly improved when the emission inventory of anthropogenic sources is amended by satellite-derived estimates of BC emissions from fires. Both BC concentrations (R2=0.89, P<0.05) and source contributions (R2=0.77, P<0.05) are accurately mimicked and linked to predominantly European emissions. This improved model skill allows for more accurate assessment of sources and effects of BC in the Arctic, and a more credible scientific underpinning of policy efforts aimed at efficiently reducing BC emissions reaching the European Arctic. PMID:27627859

Initial experience with a radiology imaging network to newborn and intensive care units.

PubMed

Witt, R M; Cohen, M D; Appledorn, C R

1991-02-01

A digital image network has been installed in the James Whitcomb Riley Hospital for Children on the Indiana University Medical Center to create a limited all digital imaging system. The system is composed of commercial components, Philips/AT&T CommView system, (Philips Medical Systems, Shelton, CT; AT&T Bell Laboratories, West Long Beach, NJ) and connects an existing Philips Computed Radiology (PCR) system to two remote workstations that reside in the intensive care unit and the newborn nursery. The purpose of the system is to display images obtained from the PCR system on the remote workstations for direct viewing by referring clinicians, and to reduce many of their visits to the radiology reading room three floors away. The design criteria includes the ability to centrally control all image management functions on the remote workstations to relieve the clinicians from any image management tasks except for recalling patient images. The principal components of the system are the Philips PCR system, the acquisition module (AM), and the PCR interface to the Data Management Module (DMM). Connected to the DMM are an Enhanced Graphics Display Workstation (EGDW), an optical disk drive, and a network gateway to an ethernet link. The ethernet network is the connection to the two Results Viewing Stations (RVS) and both RVSs are approximately 100 m from the gateway. The DMM acts as an image file server and an image archive device. The DMM manages the image data base and can load images to the EGDW and the two RVSs. The system has met the initial design specifications and can successfully capture images from the PCR and direct them to the RVSs.(ABSTRACT TRUNCATED AT 250 WORDS)

Correlates of sexual initiation among European adolescents

PubMed Central

Carli, Vladimir; Hadlaczky, Gergö; Sarchiapone, Marco; Apter, Alan; Balazs, Judit; Banzer, Raphaela; Bobes, Julio; Brunner, Romuald; Cosman, Doina; Farkas, Luca; Haring, Christian; Hoven, Christina W.; Kaess, Michael; Kahn, Jean Pierre; McMahon, Elaine; Postuvan, Vita; Sisask, Merike; Värnik, Airi; Zadravec Sedivy, Nusa; Wasserman, Danuta

2018-01-01

initiation among boys. Significant predictors included also being bullied, fighting, truancy, and low parental involvement. Conclusions Adolescent sexual behaviours are related to non-sexual risk behaviours, psychological difficulties and contextual vulnerabilities. While gateway effects explain some associations, a comprehensive model is needed to understand adolescent sexual behaviours, their physical, mental, and social health outcomes, and their potential positive effects on wellbeing. Tailored interventions may need to consider younger girls as a particularly vulnerable group in view of a strong association between non-sexual and sexual behaviors. PMID:29420612

Gateway to understanding: Indigenous ecological activism and education in urban, rural, and remote contexts

NASA Astrophysics Data System (ADS)

Lowan-Trudeau, Gregory

2017-03-01

This article is a response to Kassam, Avery, and Ruelle's insights as presented in this forum on rural science education. Topics considered include troubling the urban/rural divide in the context of Indigenous knowledge and expanding to include the common Canadian notion of the "remote", a designation rooted in our national colonial narrative for the mythic, typically northern, wilderness sparsely inhabited by primarily Indigenous peoples. These concepts are further considered through exploration of Indigenous and allied ecological activism in Canada and the United States related to the proposed Northern Gateway and Keystone XL pipelines. This discussion concludes with an argument for the inherent pedagogical opportunity presented by such cases for contemporary educators to engage students in consideration of wicked problems, geographically rooted cognitive diversity, and the legal, economic, ecological, and cultural underpinnings and ramifications of the current events prominent in their home communities and abroad.

Gateways to clinical trials.

PubMed

Bayés, M; Rabasseda, X; Prous, J R

2005-06-01

Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: Abiraterone acetate, acyline, adalimumab, adenosine triphosphate, AEE-788, AIDSVAX gp120 B/B, AK-602, alefacept, alemtuzumab, alendronic acid sodium salt, alicaforsen sodium, alprazolam, amdoxovir, AMG-162, aminolevulinic acid hydrochloride, aminolevulinic acid methyl ester, aminophylline hydrate, anakinra, anecortave acetate, anti-CTLA-4 MAb, APC-8015, aripiprazole, aspirin, atazanavir sulfate, atomoxetine hydrochloride, atorvastatin calcium, atrasentan, AVE-5883, AZD-2171; Betamethasone dipropionate, bevacizumab, bimatoprost, biphasic human insulin (prb), bortezomib, BR-A-657, BRL-55730, budesonide, busulfan; Calcipotriol, calcipotriol/betamethasone dipropionate, calcium folinate, capecitabine, capravirine, carmustine, caspofungin acetate, cefdinir, certolizumab pegol, CG-53135, chlorambucil, ciclesonide, ciclosporin, cisplatin, clofarabine, clopidogrel hydrogensulfate, clozapine, co-trimoxazole, CP-122721, creatine, CY-2301, cyclophosphamide, cypher, cytarabine, cytolin; D0401, darbepoetin alfa, darifenacin hydrobromide, DASB, desipramine hydrochloride, desloratadine, desvenlafaxine succinate, dexamethasone, didanosine, diquafosol tetrasodium, docetaxel, doxorubicin hydrochloride, drotrecogin alfa (activated), duloxetine hydrochloride, dutasteride; Ecallantide, efalizumab, efavirenz, eletriptan, emtricitabine, enfuvirtide, enoxaparin sodium, estramustine phosphate sodium, etanercept, ethinylestradiol, etonogestrel, etonogestrel/ethinylestradiol, etoposide, exenatide; Famciclovir, fampridine, febuxostat, filgrastim, fludarabine phosphate, fluocinolone acetonide, fluorouracil, fluticasone propionate

IoT gateways, cloud and the last mile for energy efficiency and sustainability in the era of CPS expansion: "A bot is irrigating my farm.. "

NASA Astrophysics Data System (ADS)

Papageorgas, Panagiotis G.; Agavanakis, Kyriakos; Dogas, Ioannis; Piromalis, Dimitrios D.

2018-05-01

A cloud-based architecture is presented for the internetworking of sensors and actuators through a universal gateway, network server and application user interface design. The proposed approach targets to Energy Efficiency and sustainability in a holistic way, by integrating an open-source test bed prototype based on long-range low-bandwidth wireless networking technology for sensing and actuation as the elementary block of a viable, cost-effective and reliable solution. The prototype presented is capable of supporting both sensors and actuators, processing data locally and transmitting the results of the imposed computations to a higher level node. Additionally, it is combined with a service-oriented architecture and involves publish/subscribe middleware protocols and cloud technology to confront with the system needs in terms of data volume and processing power. In this context, the integration of instant message (chat) services is demonstrated so that they can be part of an emerging global-scope eco-system of Cyber-Physical Systems to support a wide variety of IoT applications, with strong advantages such as usability, scalability and security, while adopting a unified gateway design and a simple - yet powerful - user interface.

A cognitive gateway-based spectrum sharing method in downlink round robin scheduling of LTE system

NASA Astrophysics Data System (ADS)

Deng, Hongyu; Wu, Cheng; Wang, Yiming

2017-07-01

A key technique of LTE is how to allocate efficiently the resource of radio spectrum. Traditional Round Robin (RR) scheduling scheme may lead to too many resource residues when allocating resources. When the number of users in the current transmission time interval (TTI) is not the greatest common divisor of resource block groups (RBGs), and such a phenomenon lasts for a long time, the spectrum utilization would be greatly decreased. In this paper, a novel spectrum allocation scheme of cognitive gateway (CG) was proposed, in which the LTE spectrum utilization and CG’s throughput were greatly increased by allocating idle resource blocks in the shared TTI in LTE system to CG. Our simulation results show that the spectrum resource sharing method can improve LTE spectral utilization and increase the CG’s throughput as well as network use time.

EPA Remote Sensing Information Gateway

NASA Astrophysics Data System (ADS)

Paulsen, H. K.; Szykman, J. J.; Plessel, T.; Freeman, M.; Dimmick, F.

2009-12-01

The Remote Sensing Information Gateway was developed by the U.S. Environmental Protection Agency (EPA) to assist researchers in easily obtaining and combining a variety of environmental datasets related to air quality research. Current datasets available include, but are not limited to surface PM2.5 and O3 data, satellite derived aerosol optical depth , and 3-dimensional output from U.S. EPA's Models 3/Community Multi-scale Air Quality (CMAQ) modeling system. The presentation will include a demonstration that illustrates several scenarios of how researchers use the tool to help them visualize and obtain data for their work; with a particular focus on episode analysis related to biomass burning impacts on air quality. The presentation will provide an overview on how RSIG works and how the code has been—and can be—adapted for other projects. One example is the Virtual Estuary, which focuses on automating the retrieval and pre-processing of a variety of data needed for estuarine research. RSIG’s source codes are freely available to researchers with permission from the EPA principal investigator, Dr. Jim Szykman. RSIG is available to the community and can be accessed online at http://www.epa.gov/rsig. Once the JAVA policy file is configured on your computer you can run the RSIG applet on your computer and connect to the RSIG server to visualize and retrieve available data sets. The applet allows the user to specify the temporal/spatial areas of interest, and the types of data to retrieve. The applet then communicates with RSIG subsetter codes located on the data owners’ remote servers; the subsetter codes assemble and transfer via ordinary Internet protocols only the specified data to the researcher’s computer. This is much faster than the usual method of transferring large files via FTP and greatly reduces network traffic. The RSIG applet then visualizes the transferred data on a latitude-longitude map, automatically locating the data in the correct

SafeTrip 21 initiative : networked traveler foresighted driving field experiment, final report.

DOT National Transportation Integrated Search

2011-04-01

The Networked Traveler Project was originally conceived to leverage the explosive rise of smartphones as a : communications gateway to bring real-time traveler assistance concepts from the ITS community to the American : people. The Networked Travele...

Framework for ReSTful Web Services in OSGi

NASA Technical Reports Server (NTRS)

Shams, Khawaja S.; Norris, Jeffrey S.; Powell, Mark W.; Crockett, Thomas M.; Mittman, David S.; Fox, Jason M.; Joswig, Joseph C.; Wallick, Michael N.; Torres, Recaredo J.; Rabe, Kenneth

2009-01-01

Ensemble ReST is a software system that eases the development, deployment, and maintenance of server-side application programs to perform functions that would otherwise be performed by client software. Ensemble ReST takes advantage of the proven disciplines of ReST (Representational State Transfer. ReST leverages the standardized HTTP protocol to enable developers to offer services to a diverse variety of clients: from shell scripts to sophisticated Java application suites

Internet Technology in Magnetic Resonance: A Common Gateway Interface Program for the World-Wide Web NMR Spectrometer

NASA Astrophysics Data System (ADS)

Buszko, Marian L.; Buszko, Dominik; Wang, Daniel C.

1998-04-01

A custom-written Common Gateway Interface (CGI) program for remote control of an NMR spectrometer using a World Wide Web browser has been described. The program, running on a UNIX workstation, uses multiple processes to handle concurrent tasks of interacting with the user and with the spectrometer. The program's parent process communicates with the browser and sends out commands to the spectrometer; the child process is mainly responsible for data acquisition. Communication between the processes is via the shared memory mechanism. The WWW pages that have been developed for the system make use of the frames feature of web browsers. The CGI program provides an intuitive user interface to the NMR spectrometer, making, in effect, a complex system an easy-to-use Web appliance.

Smokeless tobacco: a gateway to smoking or a way away from smoking.

PubMed

Melikian, Assieh A; Hoffmann, Dietrich

2009-07-01

Recently, tobacco companies have been marketing moist smokeless tobacco products that are 'spitless'. These products have lower concentrations of tobacco-specific nitrosamines and of other harmful chemicals than other tobacco products, but can deliver relatively high doses of nicotine. They are packaged in small sachets, similar to tea bags that are placed between cheek and gum. Global promotion of smokeless tobacco products is hotly debated among tobacco control and public health experts. Proponents point to the Swedish experience where snus (Swedish moist snuff) is widely used as an alternative to cigarette smoking among men. Meanwhile, Sweden has low rates of smoking and a lower rate of respiratory diseases and lung cancers by comparison to other developed countries. The opponents argue that snus has its own risks, that no form of tobacco should ever be promoted; and that 'snus is culture-bound and not transferable to other settings'. Critics also suspect that the tobacco industry will use snus marketing as a 'gateway' to promote cigarettes among young people. Research on the effects of marketing snus to smokers is too limited to support using snus as a harm-reduction tool, and the epidemiological data are not conclusive.

The Importance of Conducting Life Sciences Experiments on the Deep Space Gateway Platform

NASA Technical Reports Server (NTRS)

Bhattacharya, S.

2018-01-01

Over the last several decades important information has been gathered by conducting life science experiments on the Space Shuttle and on the International Space Station. It is now time to leverage that scientific knowledge, as well as aspects of the hardware that have been developed to support the biological model systems, to NASA's next frontier - the Deep Space Gateway. In order to facilitate long duration deep space exploration for humans, it is critical for NASA to understand the effects of long duration, low dose, deep space radiation on biological systems. While carefully controlled ground experiments on Earth-based radiation facilities have provided valuable preliminary information, we still have a significant knowledge gap on the biological responses of organisms to chronic low doses of the highly ionizing particles encountered beyond low Earth orbit. Furthermore, the combined effects of altered gravity and radiation have the potential to cause greater biological changes than either of these parameters alone. Therefore a thorough investigation of the biological effects of a cis-lunar environment will facilitate long term human exploration of deep space.

The spatial data and knowledge gateways at the International Water Management Institute (IWMI)

NASA Astrophysics Data System (ADS)

Thenkabail, P. S.; Biradar, C. M.; Noojipady, P.; Islam, A.; Velpuri, M.; Vithanage, J.; Kulawardhana, W.; Li, Yuan Jie; Dheeravath, V.; Gunasinghe, S.; Alankara, R.

2006-10-01

In this paper we discuss spatial data and knowledge base (SDKB) gateway portals developed by the International Water Management Institute (IWMI). Our vision is to generate and/or facilitate easy and free access to state-of-art SDKB of excellence globally. Our mission is to make SDKB accessible online, globally, for free. The IWMI data storehouse pathway (IWMIDSP; http://www.iwmidsp.org) is a pathfinder global public good (GPG) portal on remote sensing and GIS (RS/GIS) data and products with specific emphasis on river basin data, but also storing valuable data on Nations, Regions, and the World. A number of other specialty GPG portals have also been released. These include Global map of irrigated area (http://www.iwmigiam.org), Drought monitoring system for southwest Asia (http://dms.iwmi.org), Tsunami satellite sensor data catalogue (http://tsdc.iwmi.org), and Knowledge base system (KBS) for Sri Lanka (http://www.iwmikbs.org). The IWMIDSP has been the backbone of several other projects such as global irrigated area mapping, drought monitoring system, wetlands, and knowledge base systems. A discussion on these pathfinder web portals follow.

A Comparative Study of Students Active and Inactive in Extracurricular Activities While Enrolled in Second Year Associate Degree Programs on the Kenosha and Racine Campuses of Gateway Technical Institute, Kenosha, Wisconsin.

ERIC Educational Resources Information Center

Rinck, Lorna Lee

Students at Gateway Technical Institute were surveyed to determine their attitudes toward extracurricular activities, e.g., campus activities, advisors and sponsors, the effect of outside forces on school activities, extended athletic participation by girls in interscholastic sports, administration and faculty, and leadership development. The…

Security Engineering and Educational Initiatives for Critical Information Infrastructures

DTIC Science & Technology

2013-06-01

standard for cryptographic protection of SCADA communications. The United Kingdom’s National Infrastructure Security Co-ordination Centre (NISCC...has released a good practice guide on firewall deployment for SCADA systems and process control networks [17]. Meanwhile, National Institute for ...report. APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED 18 The SCADA gateway collects the data gathered by sensors, translates them from

Finding new superconductors: the spin-fluctuation gateway to high Tc and possible room temperature superconductivity.

PubMed

Pines, David

2013-10-24

We propose an experiment-based strategy for finding new high transition temperature superconductors that is based on the well-established spin fluctuation magnetic gateway to superconductivity in which the attractive quasiparticle interaction needed for superconductivity comes from their coupling to dynamical spin fluctuations originating in the proximity of the material to an antiferromagnetic state. We show how lessons learned by combining the results of almost three decades of intensive experimental and theoretical study of the cuprates with those found in the decade-long study of a strikingly similar family of unconventional heavy electron superconductors, the 115 materials, can prove helpful in carrying out that search. We conclude that, since Tc in these materials scales approximately with the strength of the interaction, J, between the nearest neighbor local moments in their parent antiferromagnetic state, there may not be a magnetic ceiling that would prevent one from discovering a room temperature superconductor.

Vaping as a Catalyst for Smoking? An Initial Model on the Initiation of Electronic Cigarette Use and the Transition to Tobacco Smoking Among Adolescents.

PubMed

Schneider, Sven; Diehl, Katharina

2016-05-01

The popularity of electronic cigarettes (e-cigarettes) among adolescents is growing worldwide. A more accurate model than the much discussed but inadequate Gateway Hypothesis is needed to explain some adolescents' initial preference for e-cigarettes over tobacco cigarettes, as well as any transition from e-cigarettes to tobacco smoking. Our aim was to summarize the diffuse fear that adolescents will be indirectly encouraged to begin smoking tobacco via the use of e-cigarettes and to systematize the disparate causal hypotheses used thus far in relevant literature. We summarized the vague and fragmented hypotheses formulated thus far in literature on both trajectories from abstinence to e-cigarette use and from there to tobacco smoking into a set of empirically testable hypotheses and organized them into a comprehensive model. Our results indicate that the perceived health risks, specific product characteristics (such as taste, price and inconspicuous use), and higher levels of acceptance among peers and others potentially make e-cigarettes initially more attractive to adolescents than tobacco cigarettes. Later, increasing familiarity with nicotine could lead to the reevaluation of both electronic and tobacco cigarettes and subsequently to a potential transition to tobacco smoking. The suggested "catalyst model" takes variations in the nicotine content of e-cigarettes as well as the dual use of different substances into account. Our model provides causal hypotheses for the initiation of e-cigarette use and for the potential transition to tobacco smoking which, after being tested in empirical studies, could lead to the formulation of concrete recommendations for healthcare intervention and prevention measures. We developed a model that provides causal hypotheses for the initiation of e-cigarette use and for the potential transition to tobacco smoking. © The Author 2015. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco

Agile and Adaptive IT Ecosystem, Results, Outlook, and Recommendations

DTIC Science & Technology

2014-06-01

http://netbeans.dzone.com/news/war-fighter- netbeans -platform 5 http://www.afei.org/events/4A07/Documents/1-DI2E%20Brochure%20ISA_10APR13.pdf 6...Client ( NetBeans ), and OSGI bundles (Karafe). DoD systems also use both the Android and iOS mobile operating systems. Each technology has a specific

Internet Technology in Magnetic Resonance: A Common Gateway Interface Program for the World-Wide Web NMR Spectrometer

PubMed

Buszko; Buszko; Wang

1998-04-01

A custom-written Common Gateway Interface (CGI) program for remote control of an NMR spectrometer using a World Wide Web browser has been described. The program, running on a UNIX workstation, uses multiple processes to handle concurrent tasks of interacting with the user and with the spectrometer. The program's parent process communicates with the browser and sends out commands to the spectrometer; the child process is mainly responsible for data acquisition. Communication between the processes is via the shared memory mechanism. The WWW pages that have been developed for the system make use of the frames feature of web browsers. The CGI program provides an intuitive user interface to the NMR spectrometer, making, in effect, a complex system an easy-to-use Web appliance. Copyright 1998 Academic Press.

Distributed Earth observation data integration and on-demand services based on a collaborative framework of geospatial data service gateway

NASA Astrophysics Data System (ADS)

Xie, Jibo; Li, Guoqing

2015-04-01

Earth observation (EO) data obtained by air-borne or space-borne sensors has the characteristics of heterogeneity and geographical distribution of storage. These data sources belong to different organizations or agencies whose data management and storage methods are quite different and geographically distributed. Different data sources provide different data publish platforms or portals. With more Remote sensing sensors used for Earth Observation (EO) missions, different space agencies have distributed archived massive EO data. The distribution of EO data archives and system heterogeneity makes it difficult to efficiently use geospatial data for many EO applications, such as hazard mitigation. To solve the interoperable problems of different EO data systems, an advanced architecture of distributed geospatial data infrastructure is introduced to solve the complexity of distributed and heterogeneous EO data integration and on-demand processing in this paper. The concept and architecture of geospatial data service gateway (GDSG) is proposed to build connection with heterogeneous EO data sources by which EO data can be retrieved and accessed with unified interfaces. The GDSG consists of a set of tools and service to encapsulate heterogeneous geospatial data sources into homogenous service modules. The GDSG modules includes EO metadata harvesters and translators, adaptors to different type of data system, unified data query and access interfaces, EO data cache management, and gateway GUI, etc. The GDSG framework is used to implement interoperability and synchronization between distributed EO data sources with heterogeneous architecture. An on-demand distributed EO data platform is developed to validate the GDSG architecture and implementation techniques. Several distributed EO data achieves are used for test. Flood and earthquake serves as two scenarios for the use cases of distributed EO data integration and interoperability.

Dielectric studies on struvite urinary crystals, a gateway to the new treatment modality for urolithiasis

NASA Astrophysics Data System (ADS)

Rajan, Reshma; Raj, N. Arunai Nambi; Madeswaran, S.; Babu, D. Rajan

2015-09-01

Struvite or magnesium ammonium phosphate hexahydrate (MAPH) are biological crystals, found in the kidney, which are formed due to the infection caused by urea splitting bacteria in the urinary tract. The struvite crystals observe different morphologies and were developed using single diffusion gel growth technique. The crystalline nature and its composition were studied from different characterization techniques like X-ray Diffraction (XRD) and FTIR. The dielectric behavior of the developed crystal was studied by varying temperature and at different frequencies. The parameters like dielectric constant, dielectric loss, ac conductivity, ac resistivity, impedance and admittance of the struvite crystals were calculated. The studies proved that the dielectric loss or dissipation heat is high in lower frequencies at normal body temperature, which develops a plasma state in the stones and in turn leads to the disintegration of urinary stones. The dielectric nature of the stones leads to the dielectric therapy, which will be a gateway for future treatment modality for urolithiasis.

Earth science big data at users' fingertips: the EarthServer Science Gateway Mobile

NASA Astrophysics Data System (ADS)

Barbera, Roberto; Bruno, Riccardo; Calanducci, Antonio; Fargetta, Marco; Pappalardo, Marco; Rundo, Francesco

2014-05-01

The EarthServer project (www.earthserver.eu), funded by the European Commission under its Seventh Framework Program, aims at establishing open access and ad-hoc analytics on extreme-size Earth Science data, based on and extending leading-edge Array Database technology. The core idea is to use database query languages as client/server interface to achieve barrier-free "mix & match" access to multi-source, any-size, multi-dimensional space-time data -- in short: "Big Earth Data Analytics" - based on the open standards of the Open Geospatial Consortium Web Coverage Processing Service (OGC WCPS) and the W3C XQuery. EarthServer combines both, thereby achieving a tight data/metadata integration. Further, the rasdaman Array Database System (www.rasdaman.com) is extended with further space-time coverage data types. On server side, highly effective optimizations - such as parallel and distributed query processing - ensure scalability to Exabyte volumes. In this contribution we will report on the EarthServer Science Gateway Mobile, an app for both iOS and Android-based devices that allows users to seamlessly access some of the EarthServer applications using SAML-based federated authentication and fine-grained authorisation mechanisms.

Healthcare Data Gateways: Found Healthcare Intelligence on Blockchain with Novel Privacy Risk Control.

PubMed

Yue, Xiao; Wang, Huiju; Jin, Dawei; Li, Mingqiang; Jiang, Wei

2016-10-01

Healthcare data are a valuable source of healthcare intelligence. Sharing of healthcare data is one essential step to make healthcare system smarter and improve the quality of healthcare service. Healthcare data, one personal asset of patient, should be owned and controlled by patient, instead of being scattered in different healthcare systems, which prevents data sharing and puts patient privacy at risks. Blockchain is demonstrated in the financial field that trusted, auditable computing is possible using a decentralized network of peers accompanied by a public ledger. In this paper, we proposed an App (called Healthcare Data Gateway (HGD)) architecture based on blockchain to enable patient to own, control and share their own data easily and securely without violating privacy, which provides a new potential way to improve the intelligence of healthcare systems while keeping patient data private. Our proposed purpose-centric access model ensures patient own and control their healthcare data; simple unified Indicator-Centric Schema (ICS) makes it possible to organize all kinds of personal healthcare data practically and easily. We also point out that MPC (Secure Multi-Party Computing) is one promising solution to enable untrusted third-party to conduct computation over patient data without violating privacy.

TMV-Gate vectors: Gateway compatible tobacco mosaic virus based expression vectors for functional analysis of proteins

PubMed Central

Kagale, Sateesh; Uzuhashi, Shihomi; Wigness, Merek; Bender, Tricia; Yang, Wen; Borhan, M. Hossein; Rozwadowski, Kevin

2012-01-01

Plant viral expression vectors are advantageous for high-throughput functional characterization studies of genes due to their capability for rapid, high-level transient expression of proteins. We have constructed a series of tobacco mosaic virus (TMV) based vectors that are compatible with Gateway technology to enable rapid assembly of expression constructs and exploitation of ORFeome collections. In addition to the potential of producing recombinant protein at grams per kilogram FW of leaf tissue, these vectors facilitate either N- or C-terminal fusions to a broad series of epitope tag(s) and fluorescent proteins. We demonstrate the utility of these vectors in affinity purification, immunodetection and subcellular localisation studies. We also apply the vectors to characterize protein-protein interactions and demonstrate their utility in screening plant pathogen effectors. Given its broad utility in defining protein properties, this vector series will serve as a useful resource to expedite gene characterization efforts. PMID:23166857

A novel high-throughput (HTP) cloning strategy for site-directed designed chimeragenesis and mutation using the Gateway cloning system

PubMed Central

Suzuki, Yasuhiro; Kagawa, Naoko; Fujino, Toru; Sumiya, Tsuyoshi; Andoh, Taichi; Ishikawa, Kumiko; Kimura, Rie; Kemmochi, Kiyokazu; Ohta, Tsutomu; Tanaka, Shigeo

2005-01-01

There is an increasing demand for easy, high-throughput (HTP) methods for protein engineering to support advances in the development of structural biology, bioinformatics and drug design. Here, we describe an N- and C-terminal cloning method utilizing Gateway cloning technology that we have adopted for chimeric and mutant genes production as well as domain shuffling. This method involves only three steps: PCR, in vitro recombination and transformation. All three processes consist of simple handling, mixing and incubation steps. We have characterized this novel HTP method on 96 targets with >90% success. Here, we also discuss an N- and C-terminal cloning method for domain shuffling and a combination of mutation and chimeragenesis with two types of plasmid vectors. PMID:16009811

Interhospital network system using the worldwide web and the common gateway interface.

PubMed

Oka, A; Harima, Y; Nakano, Y; Tanaka, Y; Watanabe, A; Kihara, H; Sawada, S

1999-05-01

We constructed an interhospital network system using the worldwide web (WWW) and the Common Gateway Interface (CGI). Original clinical images are digitized and stored as a database for educational and research purposes. Personal computers (PCs) are available for data treatment and browsing. Our system is simple, as digitized images are stored into a Unix server machine. Images of important and interesting clinical cases are selected and registered into the image database using CGI. The main image format is 8- or 12-bit Joint Photographic Experts Group (JPEG) image. Original clinical images are finally stored in CD-ROM using a CD recorder. The image viewer can browse all of the images for one case at once as thumbnail pictures; image quality can be selected depending on the user's purpose. Using the network system, clinical images of interesting cases can be rapidly transmitted and discussed with other related hospitals. Data transmission from relational hospitals takes 1 to 2 minutes per 500 Kbyte of data. More distant hospitals (e.g., Rakusai Hospital, Kyoto) takes 1 minute more. The mean number of accesses our image database in a recent 3-month period was 470. There is a total about 200 cases in our image database, acquired over the past 2 years. Our system is useful for communication and image treatment between hospitals and we will describe the elements of our system and image database.

78 FR 78384 - Certain Tires and Products Containing Same; Commission Determination Not to Review an Initial...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-26

... accessing its Internet server at http://www.usitc.gov . The public record for this investigation may be...; Shandong Linglong Tyre Co., Ltd. of Zhaoyuan City, China; Dunlap & Kyle Company, Inc., d/b/a Gateway Tire...

Geopan AT@S: a Brokering Based Gateway to Georeferenced Historical Maps for Risk Analysis

NASA Astrophysics Data System (ADS)

Previtali, M.

2017-08-01

Importance of ancient and historical maps is nowadays recognized in many applications (e.g., urban planning, landscape valorisation and preservation, land changes identification, etc.). In the last years a great effort has been done by different institutions, such as Geographical Institutes, Public Administrations, and collaborative communities, for digitizing and publishing online collections of historical maps. In spite of this variety and availability of data, information overload makes difficult their discovery and management: without knowing the specific repository where the data are stored, it is difficult to find the information required. In addition, problems of interconnection between different data sources and their restricted interoperability may arise. This paper describe a new brokering based gateway developed to assure interoperability between data, in particular georeferenced historical maps and geographic data, gathered from different data providers, with various features and referring to different historical periods. The developed approach is exemplified by a new application named GeoPAN Atl@s that is aimed at linking in Northern Italy area land changes with risk analysis (local seismicity amplification and flooding risk) by using multi-temporal data sources and historic maps.

MultiSite Gateway-Compatible Cell Type-Specific Gene-Inducible System for Plants1[OPEN

PubMed Central

Siligato, Riccardo; Wang, Xin; Yadav, Shri Ram; Lehesranta, Satu; Ma, Guojie; Ursache, Robertas; Sevilem, Iris; Zhang, Jing; Gorte, Maartje; Prasad, Kalika; Heidstra, Renze

2016-01-01

A powerful method to study gene function is expression or overexpression in an inducible, cell type-specific system followed by observation of consequent phenotypic changes and visualization of linked reporters in the target tissue. Multiple inducible gene overexpression systems have been developed for plants, but very few of these combine plant selection markers, control of expression domains, access to multiple promoters and protein fusion reporters, chemical induction, and high-throughput cloning capabilities. Here, we introduce a MultiSite Gateway-compatible inducible system for Arabidopsis (Arabidopsis thaliana) plants that provides the capability to generate such constructs in a single cloning step. The system is based on the tightly controlled, estrogen-inducible XVE system. We demonstrate that the transformants generated with this system exhibit the expected cell type-specific expression, similar to what is observed with constitutively expressed native promoters. With this new system, cloning of inducible constructs is no longer limited to a few special cases but can be used as a standard approach when gene function is studied. In addition, we present a set of entry clones consisting of histochemical and fluorescent reporter variants designed for gene and promoter expression studies. PMID:26644504

Implementation of a real-time multi-channel gateway server in ubiquitous integrated biotelemetry system for emergency care (UIBSEC).

PubMed

Cheon, Gyeongwoo; Shin, Il Hyung; Jung, Min Yang; Kim, Hee Chan

2009-01-01

We developed a gateway server to support various types of bio-signal monitoring devices for ubiquitous emergency healthcare in a reliable, effective, and scalable way. The server provides multiple channels supporting real-time N-to-N client connections. We applied our system to four types of health monitoring devices including a 12-channel electrocardiograph (ECG), oxygen saturation (SpO(2)), and medical imaging devices (a ultrasonograph and a digital skin microscope). Different types of telecommunication networks were tested: WIBRO, CDMA, wireless LAN, and wired internet. We measured the performance of our system in terms of the transmission rate and the number of simultaneous connections. The results show that the proposed network communication strategy can be successfully applied to the ubiquitous emergency healthcare service by providing a fast rate enough for real-time video transmission and multiple connections among patients and medical personnel.

Baker-Barry Tunnel Lighting: Evaluation of a Potential GATEWAY Demonstrations Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tuenge, Jason R.

2011-06-28

The U.S. Department of Energy is evaluating the Baker-Barry Tunnel as a potential GATEWAY Demonstrations project for deployment of solid-state lighting (SSL) technology. The National Park Service views this project as a possible proving ground and template for implementation of light-emitting diode (LED) luminaires in other tunnels, thereby expanding the estimated 40% energy savings from 132 MWh/yr to a much larger figure nationally. Most of the energy savings in this application is attributable to the instant-restrike capability of LED products and to their high tolerance for frequent on/off switching, used here to separately control either end of the tunnel duringmore » daytime hours. Some LED luminaires rival or outperform their high-intensity discharge (HID) counterparts in terms of efficacy, but options are limited, and smaller lumen packages preclude true one-for-one equivalence. However, LED products continue to improve in efficacy and affordability at a rate unmatched by other light source technologies; the estimated simple payback period of eight years (excluding installation costs and maintenance savings) can be expected to improve with time. The proposed revisions to the existing high-pressure sodium (HPS) lighting system would require slightly increased controls complexity and significantly increased luminaire types and quantities. In exchange, substantial annual savings (from reduced maintenance and energy use) would be complemented by improved quantity and quality of illumination. Although advanced lighting controls could offer additional savings, it is unclear whether such a system would prove cost-effective; this topic may be explored in future work.« less

Klimanavigator - Climate Navigator - Gateway to climate knowledge in Germany

NASA Astrophysics Data System (ADS)

Schuck-Zöller, Susanne

2013-04-01

Objective More than 50 German research institutions and networks are represented on www.klimanavigator.de, a common platform, where information about their work, and the latest findings from climate research and adaptation can be found. Thus Klimanavigator as a gateway to climate knowledge provides a information portal for those who have to respond to climate change. The internet portal gives an overview of the present state of research and is estimated as a decision support tool for appropriate mitigation and adaptation measures. Target Groups The portal collects the German climate research institutions to publish their scientific knowledge in a non-scientific language. Economists, policymakers, administration and the media are bound to find the names of scientific experts and institutions by an elaborated research tool. Methodology The chapter "Dossiers" is edited by the Klimanavigator-Coordinator CSC. It gathers information to a special issue looked upon from various points of view. Publications of outstanding German scientists are presented side by side, current knowledge is being synthesized, scientifically reviewed and disseminated. The latest news from climate and adaptation research is presented in an own chapter, dedicated to the press releases of the portal members. Via RSS-feed the press releases are collected from the different partner institutions. Thirdly, portraits of the member institutions, that are individually edited by themselves, draw a map of science in Germany and help to find appropriate cooperation partners. For the future further development is being planned. Common Management Klimanavigator is being managed by the partners in common. The main decisions concerning the concept and shape of the portal are made by the partners' assembly. An elected editorial committee decides about the content between the assemblies. The Climate Service Center (part of the Helmholtz-Zentrum Geesthacht) concentrates on facilitating the cooperation, and

What Happens when Sea Ice Retreats, Peatlands Form, and a Landbridge Drowns? A Molecular View of the Last Deglacial from the Pacific-Arctic Gateway

NASA Astrophysics Data System (ADS)

Kocis, J. J.; Petsch, S.; Castañeda, I. S.; Brigham-Grette, J.

2014-12-01

Arctic peatlands and thermokarst lakes (TK) are thought to play a significant role in changing atmospheric methane concentration (AMC) during the last deglacial. However, there is debate concerning timing of their initiation and extent they drove variations in AMC. Models show sea ice cover (SIC) and sea surface temperatures (SSTs) can also play a significant role. Yet, changes in peatland/TK lake areal extent in response to those dynamics as continental shelves were submerged are often not considered. To examine such connections, we report on molecular proxies in marine records that reveal change in terrestrial organic matter (TOM) export, SIC, and SSTs as sea levels rose during the last 18 ka in the Pacific-Arctic Gateway. Here, TOM input to the ocean was tracked by measuring the flux of branched glycerol dialkyl glycerol tetraethers, n-alkyl lipids, and pentacyclic triterpenoids. SIC and SSTs were reconstructed using modern calibrations of highly branched isoprenoid alkene abundances in surface sediments from the Bering and Chukchi Seas. SSTs were also reconstructed based on the relative abundance of isoprenoid glycerol dialkyl glycerol tetraethers. Our sediment records reveal increased flux of TOM coincides with peatland/TK lake initiation, reduced SIC (~20%), and warmer SSTs (~4°C) as AMC increased during the Bølling-Allerød (BA). Terrestrial flux dramatically reduced as SIC increased (~50%) and SSTs cooled as AMC fell during the Younger Dryas. Most notably, TOM export rapidly rebounds as AMC abruptly rose throughout the Holocene Thermal Maximum (HTM), when SSTs warmed by ~3°C and SIC diminished and peatland areal extent increased. Using multi-proxy evidence in combination with a simple model that accounts for submergence of peatland/TK lake area, we estimate that the exposed Beringian shelf emitted an amount of CH4 comparable to previously reported peatland emissions in Alaska during the BA and HTM. The GDGT-based methane index (MI) was <0.3 throughout

On the Capability of Smartphones to Perform as Communication Gateways in Medical Wireless Personal Area Networks

PubMed Central

Morón, María José; Luque, Rafael; Casilari, Eduardo

2014-01-01

This paper evaluates and characterizes the technical performance of medical wireless personal area networks (WPANs) that are based on smartphones. For this purpose, a prototype of a health telemonitoring system is presented. The prototype incorporates a commercial Android smartphone, which acts as a relay point, or “gateway”, between a set of wireless medical sensors and a data server. Additionally, the paper investigates if the conventional capabilities of current commercial smartphones can be affected by their use as gateways or “Holters” in health monitoring applications. Specifically, the profiling has focused on the CPU and power consumption of the mobile devices. These metrics have been measured under several test conditions modifying the smartphone model, the type of sensors connected to the WPAN, the employed Bluetooth profile (SPP (serial port profile) or HDP (health device profile)), the use of other peripherals, such as a GPS receiver, the impact of the use of the Wi-Fi interface or the employed method to encode and forward the data that are collected from the sensors. PMID:24451456

In-Frame and Unmarked Gene Deletions in Burkholderia cenocepacia via an Allelic Exchange System Compatible with Gateway Technology

PubMed Central

Fazli, Mustafa; Harrison, Joe J.; Gambino, Michela; Givskov, Michael

2015-01-01

Burkholderia cenocepacia is an emerging opportunistic pathogen causing life-threatening infections in immunocompromised individuals and in patients with cystic fibrosis, which are often difficult, if not impossible, to treat. Understanding the genetic basis of virulence in this emerging pathogen is important for the development of novel treatment regimes. Generation of deletion mutations in genes predicted to encode virulence determinants is fundamental to investigating the mechanisms of pathogenesis. However, there is a lack of appropriate selectable and counterselectable markers for use in B. cenocepacia, making its genetic manipulation problematic. Here we describe a Gateway-compatible allelic exchange system based on the counterselectable pheS gene and the I-SceI homing endonuclease. This system provides efficiency in cloning homology regions of target genes and allows the generation of precise and unmarked gene deletions in B. cenocepacia. As a proof of concept, we demonstrate its utility by deleting the Bcam1349 gene, encoding a cyclic di-GMP (c-di-GMP)-responsive regulator protein important for biofilm formation. PMID:25795676

Virtual Labs (Science Gateways) as platforms for Free and Open Source Science

NASA Astrophysics Data System (ADS)

Lescinsky, David; Car, Nicholas; Fraser, Ryan; Friedrich, Carsten; Kemp, Carina; Squire, Geoffrey

2016-04-01

The Free and Open Source Software (FOSS) movement promotes community engagement in software development, as well as provides access to a range of sophisticated technologies that would be prohibitively expensive if obtained commercially. However, as geoinformatics and eResearch tools and services become more dispersed, it becomes more complicated to identify and interface between the many required components. Virtual Laboratories (VLs, also known as Science Gateways) simplify the management and coordination of these components by providing a platform linking many, if not all, of the steps in particular scientific processes. These enable scientists to focus on their science, rather than the underlying supporting technologies. We describe a modular, open source, VL infrastructure that can be reconfigured to create VLs for a wide range of disciplines. Development of this infrastructure has been led by CSIRO in collaboration with Geoscience Australia and the National Computational Infrastructure (NCI) with support from the National eResearch Collaboration Tools and Resources (NeCTAR) and the Australian National Data Service (ANDS). Initially, the infrastructure was developed to support the Virtual Geophysical Laboratory (VGL), and has subsequently been repurposed to create the Virtual Hazards Impact and Risk Laboratory (VHIRL) and the reconfigured Australian National Virtual Geophysics Laboratory (ANVGL). During each step of development, new capabilities and services have been added and/or enhanced. We plan on continuing to follow this model using a shared, community code base. The VL platform facilitates transparent and reproducible science by providing access to both the data and methodologies used during scientific investigations. This is further enhanced by the ability to set up and run investigations using computational resources accessed through the VL. Data is accessed using registries pointing to catalogues within public data repositories (notably including the

Improving information retrieval with multiple health terminologies in a quality-controlled gateway.

PubMed

Soualmia, Lina F; Sakji, Saoussen; Letord, Catherine; Rollin, Laetitia; Massari, Philippe; Darmoni, Stéfan J

2013-01-01

The Catalog and Index of French-language Health Internet resources (CISMeF) is a quality-controlled health gateway, primarily for Web resources in French (n=89,751). Recently, we achieved a major improvement in the structure of the catalogue by setting-up multiple terminologies, based on twelve health terminologies available in French, to overcome the potential weakness of the MeSH thesaurus, which is the main and pivotal terminology we use for indexing and retrieval since 1995. The main aim of this study was to estimate the added-value of exploiting several terminologies and their semantic relationships to improve Web resource indexing and retrieval in CISMeF, in order to provide additional health resources which meet the users' expectations. Twelve terminologies were integrated into the CISMeF information system to set up multiple-terminologies indexing and retrieval. The same sets of thirty queries were run: (i) by exploiting the hierarchical structure of the MeSH, and (ii) by exploiting the additional twelve terminologies and their semantic links. The two search modes were evaluated and compared. The overall coverage of the multiple-terminologies search mode was improved by comparison to the coverage of using the MeSH (16,283 vs. 14,159) (+15%). These additional findings were estimated at 56.6% relevant results, 24.7% intermediate results and 18.7% irrelevant. The multiple-terminologies approach improved information retrieval. These results suggest that integrating additional health terminologies was able to improve recall. Since performing the study, 21 other terminologies have been added which should enable us to make broader studies in multiple-terminologies information retrieval.

Atlantic water heat transfer through the Arctic Gateway (Fram Strait) during the Last Interglacial

NASA Astrophysics Data System (ADS)

Zhuravleva, Anastasia; Bauch, Henning A.; Spielhagen, Robert F.

2017-10-01

The Last Interglacial in the Arctic region is often described as a time with warmer conditions and significantly less summer sea ice than today. The role of Atlantic water (AW) as the main oceanic heat flux agent into the Arctic Ocean remains, however, unclear. Using high-resolution stable isotope and faunal records from the only deep Arctic Gateway, the Fram Strait, we note for the upper water column a diminished influence of AW and generally colder-than-Holocene surface ocean conditions. After the main Saalian deglaciation had terminated, a first intensification of northward-advected AW happened ( 124 ka). However, an intermittent sea surface cooling, triggered by meltwater release at 122 ka, caused a regional delay in the further development towards peak interglacial conditions. Maximum AW heat advection occurred during late MIS 5e (118.5-116 ka) and interrupted a longer-term cooling trend at the sea surface that started from about 120 ka on. Such a late occurrence of the major AW-derived near-surface warming in the Fram Strait - this is in stark contrast to an early warm peak in the Holocene - compares well in time with upstream records from the Norwegian Sea, altogether implying a coherent development of south-to-north ocean heat transfer through the eastern Nordic Seas and into the high Arctic during the Last Interglacial.

Gateway Vectors for Efficient Artificial Gene Assembly In Vitro and Expression in Yeast Saccharomyces cerevisiae

PubMed Central

Giuraniuc, Claudiu V.; MacPherson, Murray; Saka, Yasushi

2013-01-01

Construction of synthetic genetic networks requires the assembly of DNA fragments encoding functional biological parts in a defined order. Yet this may become a time-consuming procedure. To address this technical bottleneck, we have created a series of Gateway shuttle vectors and an integration vector, which facilitate the assembly of artificial genes and their expression in the budding yeast Saccharomyces cerevisiae. Our method enables the rapid construction of an artificial gene from a promoter and an open reading frame (ORF) cassette by one-step recombination reaction in vitro. Furthermore, the plasmid thus created can readily be introduced into yeast cells to test the assembled gene’s functionality. As flexible regulatory components of a synthetic genetic network, we also created new versions of the tetracycline-regulated transactivators tTA and rtTA by fusing them to the auxin-inducible degron (AID). Using our gene assembly approach, we made yeast expression vectors of these engineered transactivators, AIDtTA and AIDrtTA and then tested their functions in yeast. We showed that these factors can be regulated by doxycycline and degraded rapidly after addition of auxin to the medium. Taken together, the method for combinatorial gene assembly described here is versatile and would be a valuable tool for yeast synthetic biology. PMID:23675537

Submarine glacial geomorphology of the Irish-UK Celtic Sea: results from the GLAMAR and GATEWAYS campaigns

NASA Astrophysics Data System (ADS)

Praeg, Daniel; McCarrron, Stephen; Dove, Dayton; Accettella, Daniella; Clarke, Cathal; Cova, Andrea; Romeo, Roberto; Scott, Gill

2013-04-01

The submarine geomorphology of the Celtic Sea is dominated by a vast system of shelf-crossing ridges, which fan seaward across up to 300 km of the mid- to outer shelf of the Irish, UK and French sectors. The ridges have long been interpreted as moribund tidal sand ridges formed during the post-glacial marine transgression, which may have reworked glacial outwash from the last British-Irish Ice Sheet (BIIS). No geomorphological evidence of the BIIS has been recognised, but a mid-shelf grounding line has been proposed based on a seaward transition from subglacial till to glaciomarine sediments at the base of several BGS vibrocores from the Irish-UK sectors. However, one of these vibrocores proved till on a ridge flank, impying ice advance across it; this has led to a model in which the ridges were formed by palaeo-tidal processes prior to or during a rapid late-glacial advance of the Irish Sea Ice Stream (ISIS) to the mid-shelf. An alternative explanation is that the ridges are glaciofluvial features, formed by subglacial meltwater drainage beneath a more extensive ice sheet. This hypothesis formed the basis of an International Polar Year project (IPY EoI 529) that has been supported by campaigns of the r/v OGS Explora in 2009 (GLAMAR) and of the r/v Celtic Voyager in 2012 (GATEWAYS). The GLAMAR campaign targeted the mid-shelf grounding line, acquiring multbeam imagery and high-resolution seismic profiles (Chirp, sparker) correlated to BGS vibrocores. The multibeam imagery revealed remarkable bedforms at various scales: en echelon ridge segments up to 7 km wide and 55 m high, giving way laterally and axially to transverse 'ribs' up to 10 m high; superimposed on both are 'crenellations' <1 m in relief, of varying backscatter. No change in these morphologies is observed within a 25 x 100 km area extending 65 km seaward of the proposed grounding line. Stratigraphic correlation of seismic profiles to BGS vibrocores confirms the ridges to be mantled by glacial till and

Remote Sensing Information Gateway: A free application and web service for fast, convenient, interoperable access to large repositories of atmospheric data

NASA Astrophysics Data System (ADS)

Plessel, T.; Szykman, J.; Freeman, M.

2012-12-01

EPA's Remote Sensing Information Gateway (RSIG) is a widely used free applet and web service for quickly and easily retrieving, visualizing and saving user-specified subsets of atmospheric data - by variable, geographic domain and time range. Petabytes of available data include thousands of variables from a set of NASA and NOAA satellites, aircraft, ground stations and EPA air-quality models. The RSIG applet is used by atmospheric researchers and uses the rsigserver web service to obtain data and images. The rsigserver web service is compliant with the Open Geospatial Consortium Web Coverage Service (OGC-WCS) standard to facilitate data discovery and interoperability. Since rsigserver is publicly accessible, it can be (and is) used by other applications. This presentation describes the architecture and technical implementation details of this successful system with an emphasis on achieving convenience, high-performance, data integrity and security.

Foot-and-mouth disease virus receptors: multiple gateways to initiate infection

USDA-ARS?s Scientific Manuscript database

Since its discovery over 100 years ago as the causative agent of foot-and-mouth disease (FMD), research has been directed at understanding the biology of the foot-and-mouth disease virus (FMDV) so as to be able to control this devastating and highly contagious disease of cloven-hoofed livestock. Giv...

In-Frame and Unmarked Gene Deletions in Burkholderia cenocepacia via an Allelic Exchange System Compatible with Gateway Technology.

PubMed

Fazli, Mustafa; Harrison, Joe J; Gambino, Michela; Givskov, Michael; Tolker-Nielsen, Tim

2015-06-01

Burkholderia cenocepacia is an emerging opportunistic pathogen causing life-threatening infections in immunocompromised individuals and in patients with cystic fibrosis, which are often difficult, if not impossible, to treat. Understanding the genetic basis of virulence in this emerging pathogen is important for the development of novel treatment regimes. Generation of deletion mutations in genes predicted to encode virulence determinants is fundamental to investigating the mechanisms of pathogenesis. However, there is a lack of appropriate selectable and counterselectable markers for use in B. cenocepacia, making its genetic manipulation problematic. Here we describe a Gateway-compatible allelic exchange system based on the counterselectable pheS gene and the I-SceI homing endonuclease. This system provides efficiency in cloning homology regions of target genes and allows the generation of precise and unmarked gene deletions in B. cenocepacia. As a proof of concept, we demonstrate its utility by deleting the Bcam1349 gene, encoding a cyclic di-GMP (c-di-GMP)-responsive regulator protein important for biofilm formation. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

Are Video Games a Gateway to Gambling? A Longitudinal Study Based on a Representative Norwegian Sample.

PubMed

Molde, Helge; Holmøy, Bjørn; Merkesdal, Aleksander Garvik; Torsheim, Torbjørn; Mentzoni, Rune Aune; Hanns, Daniel; Sagoe, Dominic; Pallesen, Ståle

2018-06-05

The scope and variety of video games and monetary gambling opportunities are expanding rapidly. In many ways, these forms of entertainment are converging on digital and online video games and gambling sites. However, little is known about the relationship between video gaming and gambling. The present study explored the possibility of a directional relationship between measures of problem gaming and problem gambling, while also controlling for the influence of sex and age. In contrast to most previous investigations which are based on cross-sectional designs and non-representative samples, the present study utilized a longitudinal design conducted over 2 years (2013, 2015) and comprising 4601 participants (males 47.2%, age range 16-74) drawn from a random sample from the general population. Video gaming and gambling were assessed using the Gaming Addiction Scale for Adolescents and the Canadian Problem Gambling Index, respectively. Using an autoregressive cross-lagged structural equation model, we found a positive relationship between scores on problematic gaming and later scores on problematic gambling, whereas we found no evidence of the reverse relationship. Hence, video gaming problems appear to be a gateway behavior to problematic gambling behavior. In future research, one should continue to monitor the possible reciprocal behavioral influences between gambling and video gaming.

LGBTQ Youth's Views on Gay-Straight Alliances: Building Community, Providing Gateways, and Representing Safety and Support.

PubMed

Porta, Carolyn M; Singer, Erin; Mehus, Christopher J; Gower, Amy L; Saewyc, Elizabeth; Fredkove, Windy; Eisenberg, Marla E

2017-07-01

Gay-Straight Alliances (GSAs) are school-based clubs that can contribute to a healthy school climate for lesbian, gay, bisexual, transgender, and questioning (LGBTQ) youth. While positive associations between health behaviors and GSAs have been documented, less is known about how youth perceive GSAs. A total of 58 LGBTQ youth (14-19 years old) mentioned GSAs during go-along interviews in 3 states/provinces in North America. These 446 comments about GSAs were thematically coded and organized using Atlas.ti software by a multidisciplinary research team. A total of 3 themes describe youth-perceived attributes of GSAs. First, youth identified GSAs as an opportunity to be members of a community, evidenced by their sense of emotional connection, support and belonging, opportunities for leadership, and fulfillment of needs. Second, GSAs served as a gateway to resources outside of the GSA, such as supportive adults and informal social locations. Third, GSAs represented safety. GSAs positively influence the physical, social, emotional, and academic well-being of LGBTQ young people and their allies. School administrators and staff are positioned to advocate for comprehensive GSAs. Study findings offer insights about the mechanisms by which GSAs benefit youth health and well-being. © 2017, American School Health Association.

Development of a novel set of Gateway-compatible vectors for live imaging in insect cells.

PubMed

Maroniche, G A; Mongelli, V C; Alfonso, V; Llauger, G; Taboga, O; del Vas, Mariana

2011-10-01

Insect genomics is a growing area of research. To exploit fully the genomic data that are being generated, high-throughput systems for the functional characterization of insect proteins and their interactomes are required. In this work, a Gateway-compatible vector set for expression of fluorescent fusion proteins in insect cells was developed. The vector set was designed to express a protein of interest fused to any of four different fluorescent proteins [green fluorescent protein (GFP), cyan fluorescent protein (CFP), yellow fluorescent protein (YFP) and mCherry] by either the C-terminal or the N-terminal ends. Additionally, a collection of organelle-specific fluorescent markers was assembled for colocalization with fluorescent recombinant proteins of interest. Moreover, the vector set was proven to be suitable for simultaneously detecting up to three proteins by multiple labelling. The use of the vector set was exemplified by defining the subcellular distribution of Mal de Río Cuarto virus (MRCV) outer coat protein P10 and by analysing the in vivo self-interaction of the MRCV viroplasm matrix protein P9-1 in Förster resonance energy transfer (FRET) experiments. In conclusion, we have developed a valuable tool for high-throughput studies of protein subcellular localization that will aid in the elucidation of the function of newly described insect and virus proteins. © 2011 The Authors. Insect Molecular Biology © 2011 The Royal Entomological Society.

Clean water billing monitoring system using flow liquid meter sensor and SMS gateway

NASA Astrophysics Data System (ADS)

Fahmi, F.; Hizriadi, A.; Khairani, F.; Andayani, U.; Siregar, B.

2018-03-01

Public clean water company (PDAM) as a public service is designed and organized to meet the needs of the community. Currently, the number of PDAM subscribers is very big and will continue to grow, but the service and facilities to customers are still done conventionally by visiting the customer’s home to record the last position of the meter. One of the problems of PDAM is the lack of disclosure of PDAM customers’ invoice because it is only done monthly. This, of course, makes PDAM customers difficult to remember the date of payment of water account. Therefore it is difficult to maintain the efficiency. The purpose of this research is to facilitate customers of PDAM water users to know the details of water usage and the time of payment of water bills easily. It also facilitates customers in knowing information related to the form of water discharge data used, payment rates, and time grace payments using SMS Gateway. In this study, Flow Liquid Meter Sensor was used for data retrieval of water flowing in the piping system. Sensors used to require the help of Hall Effect sensor that serves to measure the speed of water discharge and placed on the pipe that has the same diameter size with the sensor diameter. The sensor will take the data from the rate of water discharge it passes; this data is the number of turns of the mill on the sensor. The results of the tests show that the built system works well in helping customers know in detail the amount of water usage in a month and the bill to be paid

Bridges or Barriers? Conceptualization of the Role of Multiple Identity Gateway Groups in Intergroup Relations.

PubMed

Levy, Aharon; Saguy, Tamar; Halperin, Eran; van Zomeren, Martijn

2017-01-01

The modern era of globalization has been accompanied by a massive growth in interconnections between groups, and has led to the sharing of multiple identities by individuals and groups. Following these developments, research has focused on the issue of multiple identities, and has shed important light on how individuals who hold these complex forms of identity feel and behave, and on the reactions they elicit from members of other groups. However, the potential of groups with such multiple identities (e.g., biracials, immigrants, etc.) to affect the intergroup relations between the groups that represent the respective sources of the different identities (e.g., Blacks and Whites, country of origin and country of residence, etc.) has not been examined to date. Accordingly, in this paper, we first systematically explore the potential of groups in which people identify with multiple social categories, or groups that are perceived as such by others, to play a role in intergroup dynamics. Next, we offer a theoretical framework outlining what functions groups of people with shared multiple identities may serve (as bridges or barriers ) by proposing how their presence may facilitate or deteriorate intergroup relations. Finally, we present recent empirical research examining how groups of people with shared multiple identities can act as gateways and bridge the cleft between two separate groups that represent the respective sources of their different identities, and discuss the theoretical and practical implications for the field of intergroup relations.

Protecting Place Through Community Alliances: Haida Gwaii Responds to the Proposed Enbridge Northern Gateway Project

NASA Astrophysics Data System (ADS)

Crist, Valine

This research contributes to the emerging dialogue concerning power relationships and the alliances that are challenging current frameworks in an attempt to create positive change. Worldwide, local people in rural places are threatened by development paradigms and conflicting social, political, economic, and ecological values. Large-scale development, such as the Enbridge Northern Gateway Project (NGP), provide a tangible example of our failing systems and make the interplay of these elements palpable. Increasingly, communities are coalescing to challenge the current models and economically motivated agendas threatening Indigenous sovereignty and local lifeways. Central to these coalitions are Indigenous peoples who are aligning with non-Indigenous neighbours to renegotiate power relationships. This research examines these dynamic alliances and uses Haida Gwaii's resistance to the NGP as an example of the formidable strength of community coalitions mobilized by intersecting values. To contextualize the NGP within the broader discourse, I problematize Canada's environmental assessment process and consider how media portrays the growing resistance to the proposed project. Drawing on information presented through the environmental assessment, I analyze the main messages and shared values of Haida Gwaii citizens opposed to the NGP. This thesis focuses on this unanimous and galvanizing resistance, which is largely motivated by the reliance on local food sources and an embodied connection to Haida Gwaii shared by Island citizens. The continued denial of Aboriginal title and rights was inherent throughout this consideration and is an underlying theme throughout the analyses.

Bridges or Barriers? Conceptualization of the Role of Multiple Identity Gateway Groups in Intergroup Relations

PubMed Central

Levy, Aharon; Saguy, Tamar; Halperin, Eran; van Zomeren, Martijn

2017-01-01

The modern era of globalization has been accompanied by a massive growth in interconnections between groups, and has led to the sharing of multiple identities by individuals and groups. Following these developments, research has focused on the issue of multiple identities, and has shed important light on how individuals who hold these complex forms of identity feel and behave, and on the reactions they elicit from members of other groups. However, the potential of groups with such multiple identities (e.g., biracials, immigrants, etc.) to affect the intergroup relations between the groups that represent the respective sources of the different identities (e.g., Blacks and Whites, country of origin and country of residence, etc.) has not been examined to date. Accordingly, in this paper, we first systematically explore the potential of groups in which people identify with multiple social categories, or groups that are perceived as such by others, to play a role in intergroup dynamics. Next, we offer a theoretical framework outlining what functions groups of people with shared multiple identities may serve (as bridges or barriers) by proposing how their presence may facilitate or deteriorate intergroup relations. Finally, we present recent empirical research examining how groups of people with shared multiple identities can act as gateways and bridge the cleft between two separate groups that represent the respective sources of their different identities, and discuss the theoretical and practical implications for the field of intergroup relations. PMID:28706501

A multisite gateway-based toolkit for targeted gene expression and hairpin RNA silencing in tomato fruits.

PubMed

Estornell, Leandro Hueso; Orzáez, Diego; López-Peña, Lucas; Pineda, Benito; Antón, María Teresa; Moreno, Vicente; Granell, Antonio

2009-04-01

A collection of fruit promoters, reporter genes and protein tags has been constructed in a triple-gateway format, a recombination-based cloning system that facilitates the tandem assembly of three DNA fragments into plant expression vectors. The new pENFRUIT collection includes, among others, the classical tomato-ripening promoters E8 and 2A11 and a set of six new tomato promoters. The new promoter activities were characterized in both transient assays and stable transgenic plants. The range of expression of the new promoters comprises strong (PNH, PLI), medium (PLE, PFF, PHD) and weak (PSN) promoters driving gene expression preferentially in the fruit, and covering a wide range of tissues and developmental stages. Together, a total of 78 possible combinations for the expression of a gene of interest in the fruit, plus a set of five reporters for new promoter analysis, was made available in the current collection. Moreover, the pENFRUIT promoter collection is adaptable to hairpin RNA strategies aimed at tissue/organ-specific gene silencing with only an additional cloning step. The pENFRUIT toolkit broadens the spectrum of promoter activities available for fruit biotechnology and fundamental research, and bypasses technical difficulties of current ligase-dependent cloning techniques in the construction of fruit expression cassettes. The pENFRUIT vector collection is available for the research community in a plasmid repository, facilitating its accessibility.

The Gateway Paper--health service delivery outside of the public sector in Pakistan.

PubMed

Nishtar, Sania

2006-12-01

As opposed to preventive healthcare where State mandated healthcare agencies play a pre-dominant role, a number of actors within the healthcare system other than the State play a role in providing personalized curative healthcare within the country. The sector constitutes a set of diverse group of doctors, nurses, pharmacists, traditional healers, drug venders as well as laboratory technicians, shopkeepers and unqualified practitioners. The services they produce include hospitals, nursing homes, maternity clinics, clinics run by a range of healthcare providers, diagnostic facilities and the sale of drugs from pharmacies and unqualified sellers. However, in some cases the distinction between public and private sector is not very clear as many public sector practitioners practice privately, legally and illegally. The sector is fragmented and characterized by a mixed ownership patterns, many types of providers and different systems of medicines. As a viewpoint on the configuration of a proposed health reform within Pakistan, the Gateway Paper flags key issues in relation to this sector. This encompasses lack of a formal regulatory mechanism for private sector providers and their delivery mechanisms, absence of a formal mechanism for building capacity and ensuring quality and absence accreditation arrangements for private hospitals and nursing homes. With this as a context recommendations focus on the nature of regulatory mechanisms and the institutional arrangements necessary support them with particular reference to quality and continuing medical. In regard to traditional medicines directions focus on exploring ways to harnessing the potential within the system in order to leverage its outreach and integrate it with the formal healthcare system. The Paper also stresses on the need to fully exploit the potential within behavioral change interventions in order improve health systems performance in Pakistan and to broaden its scope from lifestyle and prevention

SU-D-BRD-03: A Gateway for GPU Computing in Cancer Radiotherapy Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jia, X; Folkerts, M; Shi, F

Purpose: Graphics Processing Unit (GPU) has become increasingly important in radiotherapy. However, it is still difficult for general clinical researchers to access GPU codes developed by other researchers, and for developers to objectively benchmark their codes. Moreover, it is quite often to see repeated efforts spent on developing low-quality GPU codes. The goal of this project is to establish an infrastructure for testing GPU codes, cross comparing them, and facilitating code distributions in radiotherapy community. Methods: We developed a system called Gateway for GPU Computing in Cancer Radiotherapy Research (GCR2). A number of GPU codes developed by our group andmore » other developers can be accessed via a web interface. To use the services, researchers first upload their test data or use the standard data provided by our system. Then they can select the GPU device on which the code will be executed. Our system offers all mainstream GPU hardware for code benchmarking purpose. After the code running is complete, the system automatically summarizes and displays the computing results. We also released a SDK to allow the developers to build their own algorithm implementation and submit their binary codes to the system. The submitted code is then systematically benchmarked using a variety of GPU hardware and representative data provided by our system. The developers can also compare their codes with others and generate benchmarking reports. Results: It is found that the developed system is fully functioning. Through a user-friendly web interface, researchers are able to test various GPU codes. Developers also benefit from this platform by comprehensively benchmarking their codes on various GPU platforms and representative clinical data sets. Conclusion: We have developed an open platform allowing the clinical researchers and developers to access the GPUs and GPU codes. This development will facilitate the utilization of GPU in radiation therapy field.« less

Cenozoic History of the Equatorial Indian Ocean Recorded by Nd Isotopes: The Closure of the Indonesian Gateway

NASA Astrophysics Data System (ADS)

Gourlan, A. T.; Meynadier, L.; Allegre, C. J.

2005-12-01

The northward tectonic motion of the Australian plate and the evolution of the Indonesian Island Arcs through the last 20 Ma, generate changes in the flow and the origin of the circulation between the Pacific and the Southern Indian Oceans. Indeed, the emergence of the Indonesian Archipelago and probably the rapid uplift of the island of Halmahera have dramatically reduced the Indonesian Gateway. However, the precise dating of this event is still a matter of debate. The Neodymium isotopic composition of marine sediments is an extremely good proxy to reconstruct the major changes in the past ocean circulation. The residence time of Nd is shorter than the circulation time of the global ocean. Therefore, the Nd isotopic composition varies between the different ocean basins and is function of changes in source provenances, paleocirculation, orogenic processes, and intensity of weathering on the continents as well as on the volcanic arcs. To reconstruct the evolution of the oceanic flow from the Pacific to the equatorial Indian Ocean since the Miocene, we have applied on high carbonates content sediments a leaching technique using acetic acid. The reliability of our technique has been assessed by comparison with the Hydroxylamine hydrochloride technique developed by Bayon et al (1). The Nd isotopic composition is determinated in the past seawater from the record in Fe-Mn oxides. The sedimentary sequences are accurately dated using bio and chimiostratigraphy. Three ODP Sites were chosen in the Indian Ocean with a water depth ranging from 1600 to 2800 m and mutually distant by about 3000 km. From West to East: Site 761 which is at the western edge of the Indonesian Gateway on the central northeastern part of the Wombat Plateau off NW Australia, Site 757 is located on the south of the Ninetyeast ridge and Site 707 is located in the western tropical Indian Ocean near the Seychelles Islands. Our data are compared with the first results from Site 807 located in the Pacific

76 FR 3148 - National Institute on Aging; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-19

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Initial Review Group; Biological Aging... applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212...

76 FR 57064 - National Institute on Aging; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-15

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Initial Review Group, Clinical Aging... applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212...

A set of GFP-based organelle marker lines combined with DsRed-based gateway vectors for subcellular localization study in rice (Oryza sativa L.).

PubMed

Wu, Tsung-Meng; Lin, Ke-Chun; Liau, Wei-Shiang; Chao, Yun-Yang; Yang, Ling-Hung; Chen, Szu-Yun; Lu, Chung-An; Hong, Chwan-Yang

2016-01-01

In the post-genomic era, many useful tools have been developed to accelerate the investigation of gene functions. Fluorescent proteins have been widely used as protein tags for studying the subcellular localization of proteins in plants. Several fluorescent organelle marker lines have been generated in dicot plants; however, useful and reliable fluorescent organelle marker lines are lacking in the monocot model rice. Here, we developed eight different GFP-based organelle markers in transgenic rice and created a set of DsRed-based gateway vectors for combining with the marker lines. Two mitochondrial-localized rice ascorbate peroxidase genes fused to DsRed and successfully co-localized with mitochondrial-targeted marker lines verified the practical use of this system. The co-localization of GFP-fusion marker lines and DsRed-fusion proteins provide a convenient platform for in vivo or in vitro analysis of subcellular localization of rice proteins.

Multi-Modal Traveler Information System - Gateway Functional Requirements

DOT National Transportation Integrated Search

1997-11-17

The Multi-Modal Traveler Information System (MMTIS) project involves a large number of Intelligent Transportation System (ITS) related tasks. It involves research of all ITS initiatives in the Gary-Chicago-Milwaukee (GCM) Corridor which are currently...

School Education as Social and Economic Governance: Responsibilising Communities through Industry-School Engagement

ERIC Educational Resources Information Center

Kapitzke, Cushla; Hay, Stephen

2011-01-01

This article examines shifts in educational and social governance taking place in Queensland, Australia, through Education Queensland's Industry School Engagement Strategy and Gateway Schools program. This significant educational initiative is set within the context of Queensland's social investment agenda first articulated in its education policy…

Computer-Aided Acquisition and Logistic Support Gateway Development

DTIC Science & Technology

1989-09-01

The initial step integrates the current vendor interfaces (Paperless Order Processing System (POPS) and SAMXIMS Procurement by Electronic Data Exchange...Paperless Order Processing System POSIX = Portable Operating System for UNIX RFQ = Request for Quotation RS-232C = The Electronics Industries

NERIES: Seismic Data Gateways and User Composed Datasets Metadata Management

NASA Astrophysics Data System (ADS)

Spinuso, Alessandro; Trani, Luca; Kamb, Linus; Frobert, Laurent

2010-05-01

One of the NERIES EC project main objectives is to establish and improve the networking of seismic waveform data exchange and access among four main data centers in Europe: INGV, GFZ, ORFEUS and IPGP. Besides the implementation of the data backbone, several investigations and developments have been conducted in order to offer to the users the data available from this network, either programmatically or interactively. One of the challenges is to understand how to enable users` activities such as discovering, aggregating, describing and sharing datasets to obtain a decrease in the replication of similar data queries towards the network, exempting the data centers to guess and create useful pre-packed products. We`ve started to transfer this task more and more towards the users community, where the users` composed data products could be extensively re-used. The main link to the data is represented by a centralized webservice (SeismoLink) acting like a single access point to the whole data network. Users can download either waveform data or seismic station inventories directly from their own software routines by connecting to this webservice, which routes the request to the data centers. The provenance of the data is maintained and transferred to the users in the form of URIs, that identify the dataset and implicitly refer to the data provider. SeismoLink, combined with other webservices (eg EMSC-QuakeML earthquakes catalog service), is used from a community gateway such as the NERIES web portal (http://www.seismicportal.eu). Here the user interacts with a map based portlet which allows the dynamic composition of a data product, binding seismic event`s parameters with a set of seismic stations. The requested data is collected by the back-end processes of the portal, preserved and offered to the user in a personal data cart, where metadata can be generated interactively on-demand. The metadata, expressed in RDF, can also be remotely ingested. They offer rating

76 FR 24890 - National Institute on Aging; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-03

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Initial Review Group, Biological Aging... Aging, Gateway Bldg., 2c212, 7201 Wisconsin Avenue, Bethesda, MD 20814, 301-402- 7701, [email protected

Using collaborative two-stage examinations to address test anxiety in a large enrollment gateway course.

PubMed

Fournier, Kimberly A; Couret, Jannelle; Ramsay, Jason B; Caulkins, Joshua L

2017-09-01

Large enrollment foundational courses are perceived as "high stakes" because of their potential to act as barriers for progression to the next course or admittance to a program. The nature of gateway courses makes them ideal settings to explore the relationship between anxiety, pedagogical interventions, and student performance. Here, two-stage collaborative examinations were implemented to improve test-taking skills and address widespread test anxiety in an introductory human anatomy course. Test anxiety data were collected (using the Motivated Strategies for Learning Questionnaire) before the first examination and last examination. Most students experienced decreased test anxiety over the course of the semester; however, some students may have experienced performance limiting conditions due to test anxiety at the end of the semester based on academic ability in the course (in "C" students when compared to "A" students: P < 0.00006 and "B" students: P < 0.05), overall academic ability (in academically weaker students: P < 0.025), and demographic factors (in women: P < 0.025). The strongest performances on examinations were primarily observed in already academically strong students (mean individual performance: P < 0.000, mean group performance: P < 0.000). Furthermore, changes in test anxiety were not significantly associated with the group portion of the examinations. Patterns of changes in test anxiety over the course of the semester underscore a complex interaction between test anxiety, student background, and student performance. Results suggest that pathways for test anxiety in "high stakes" courses may be separate from the mechanisms responsible for the benefits of collaborative testing. Anat Sci Educ 10: 409-422. © 2017 American Association of Anatomists. © 2017 American Association of Anatomists.

Enabling Data Intensive Science through Service Oriented Science: Virtual Laboratories and Science Gateways

NASA Astrophysics Data System (ADS)

Lescinsky, D. T.; Wyborn, L. A.; Evans, B. J. K.; Allen, C.; Fraser, R.; Rankine, T.

2014-12-01

We present collaborative work on a generic, modular infrastructure for virtual laboratories (VLs, similar to science gateways) that combine online access to data, scientific code, and computing resources as services that support multiple data intensive scientific computing needs across a wide range of science disciplines. We are leveraging access to 10+ PB of earth science data on Lustre filesystems at Australia's National Computational Infrastructure (NCI) Research Data Storage Infrastructure (RDSI) node, co-located with NCI's 1.2 PFlop Raijin supercomputer and a 3000 CPU core research cloud. The development, maintenance and sustainability of VLs is best accomplished through modularisation and standardisation of interfaces between components. Our approach has been to break up tightly-coupled, specialised application packages into modules, with identified best techniques and algorithms repackaged either as data services or scientific tools that are accessible across domains. The data services can be used to manipulate, visualise and transform multiple data types whilst the scientific tools can be used in concert with multiple scientific codes. We are currently designing a scalable generic infrastructure that will handle scientific code as modularised services and thereby enable the rapid/easy deployment of new codes or versions of codes. The goal is to build open source libraries/collections of scientific tools, scripts and modelling codes that can be combined in specially designed deployments. Additional services in development include: provenance, publication of results, monitoring, workflow tools, etc. The generic VL infrastructure will be hosted at NCI, but can access alternative computing infrastructures (i.e., public/private cloud, HPC).The Virtual Geophysics Laboratory (VGL) was developed as a pilot project to demonstrate the underlying technology. This base is now being redesigned and generalised to develop a Virtual Hazards Impact and Risk Laboratory

Parent-Child Interaction Therapy and High Functioning Autism: A Conceptual Overview

ERIC Educational Resources Information Center

Masse, Joshua J.; McNeil, Cheryl B.; Wagner, Stephanie M.; Chorney, Daniel B.

2007-01-01

Externalizing behaviors are a common component of the clinical presentation of Autism Spectrum Disorders and are typically the initial focus of treatment for children within this population. This article examines the appropriateness of Parent-Child Interaction Therapy (PCIT) as a first-line, gateway treatment for preschoolers with High Functioning…

Ovarian developmental variation in the primitively eusocial wasp Ropalidia marginata suggests a gateway to worker ontogeny and the evolution of sociality.

PubMed

Shukla, Shantanu; Chandran, Swarnalatha; Gadagkar, Raghavendra

2013-01-15

Social insects are characterized by reproductive caste differentiation of colony members into one or a small number of fertile queens and a large number of sterile workers. The evolutionary origin and maintenance of such sterile workers remains an enduring puzzle in insect sociobiology. Here, we studied ovarian development in over 600 freshly eclosed, isolated, virgin female Ropalidia marginata wasps, maintained in the laboratory. The wasps differed greatly both in the time taken to develop their ovaries and in the magnitude of ovarian development despite having similar access to resources. All females started with no ovarian development at day zero, and the percentage of individuals with at least one oocyte at any stage of development increased gradually across age, reached 100% at 100 days and decreased slightly thereafter. Approximately 40% of the females failed to develop ovaries within the average ecological lifespan of the species. Age, body size and adult feeding rate, when considered together, were the most important factors governing ovarian development. We suggest that such flexibility and variation in the potential and timing of reproductive development may physiologically predispose females to accept worker roles and thus provide a gateway to worker ontogeny and the evolution of sociality.

Cannabinoid Modulation of Eukaryotic Initiation Factors (eIF2α and eIF2B1) and Behavioral Cross-Sensitization to Cocaine in Adolescent Rats.

PubMed

Melas, Philippe A; Qvist, Johanna S; Deidda, Matteo; Upreti, Chirag; Wei, Ya Bin; Sanna, Fabrizio; Fratta, Walter; Scherma, Maria; Fadda, Paola; Kandel, Denise B; Kandel, Eric R

2018-03-13

Reduced eukaryotic Initiation Factor 2 (eIF2)α phosphorylation (p-eIF2α) enhances protein synthesis, memory formation, and addiction-like behaviors. However, p-eIF2α has not been examined with regard to psychoactive cannabinoids and cross-sensitization. Here, we find that a cannabinoid receptor agonist (WIN 55,212-2 mesylate [WIN]) reduced p-eIF2α in vitro by upregulating GADD34 (PPP1R15A), the recruiter of protein phosphatase 1 (PP1). The induction of GADD34 was linked to ERK/CREB signaling and to CREB-binding protein (CBP)-mediated histone hyperacetylation at the Gadd34 locus. In vitro, WIN also upregulated eIF2B1, an eIF2 activator subunit. We next found that WIN administration in vivo reduced p-eIF2α in the nucleus accumbens of adolescent, but not adult, rats. By contrast, WIN increased dorsal striatal levels of eIF2B1 and ΔFosB among both adolescents and adults. In addition, we found cross-sensitization between WIN and cocaine only among adolescents. These findings show that cannabinoids can modulate eukaryotic initiation factors, and they suggest a possible link between p-eIF2α and the gateway drug properties of psychoactive cannabinoids. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

Fast and simultaneous detection of prominent natural antioxidants using analytical microsystems for capillary electrophoresis with a glassy carbon electrode: a new gateway to food environments.

PubMed

Blasco, Antonio Javier; Barrigas, Inés; González, María Cristina; Escarpa, Alberto

2005-12-01

This paper examines for the first time the analytical possibilities of fast and simultaneous detection of prominent natural antioxidants including examples of flavonoids and vitamins using a CE microchip with electrochemical detection (ED). Unpinched injection conditions, zone electrophoretic separation and amperometric detection were carefully assayed and optimised. Analysis involved the zone electrophoretic separation of arbutin, (+)-catechin and ascorbic acid in less than 4 min using a borate buffer (pH 9.0, 50 mM), employing 2 kV as the separation voltage and +1.0 V as the detection potential. In addition, the separation of different 'couples' of natural antioxidants of food significance including (+)-catechin and ascorbic acid, (+)-catechin and rutin, as well as arbutin and phlorizdin is proposed. To demonstrate the potential and future role of CE microsystems, analytical possibilities and a new route in the raw sample analysis are presented. The preliminary results obtained allow the proposal of CE-ED microchips as a real gateway to microanalysis in foods.

The Online Bioinformatics Resources Collection at the University of Pittsburgh Health Sciences Library System--a one-stop gateway to online bioinformatics databases and software tools.

PubMed

Chen, Yi-Bu; Chattopadhyay, Ansuman; Bergen, Phillip; Gadd, Cynthia; Tannery, Nancy

2007-01-01

To bridge the gap between the rising information needs of biological and medical researchers and the rapidly growing number of online bioinformatics resources, we have created the Online Bioinformatics Resources Collection (OBRC) at the Health Sciences Library System (HSLS) at the University of Pittsburgh. The OBRC, containing 1542 major online bioinformatics databases and software tools, was constructed using the HSLS content management system built on the Zope Web application server. To enhance the output of search results, we further implemented the Vivísimo Clustering Engine, which automatically organizes the search results into categories created dynamically based on the textual information of the retrieved records. As the largest online collection of its kind and the only one with advanced search results clustering, OBRC is aimed at becoming a one-stop guided information gateway to the major bioinformatics databases and software tools on the Web. OBRC is available at the University of Pittsburgh's HSLS Web site (http://www.hsls.pitt.edu/guides/genetics/obrc).

Carnegie Math Pathways 2015-2016 Impact Report: A Five-Year Review. Carnegie Math Pathways Technical Report

ERIC Educational Resources Information Center

Hoang, Hai; Huang, Melrose; Sulcer, Brian; Yesilyurt, Suleyman

2017-01-01

College math is a gateway course that has become a constraining gatekeeper for tens of thousands of students annually. Every year, over 500,000 students fail developmental mathematics, preventing them from achieving their college and career goals. The Carnegie Math Pathways initiative offers students an alternative. It comprises two Pathways…

Front End Software for Online Database Searching Part 1: Definitions, System Features, and Evaluation.

ERIC Educational Resources Information Center

Hawkins, Donald T.; Levy, Louise R.

1985-01-01

This initial article in series of three discusses barriers inhibiting use of current online retrieval systems by novice users and notes reasons for front end and gateway online retrieval systems. Definitions, front end features, user interface, location (personal computer, host mainframe), evaluation, and strengths and weaknesses are covered. (16…

Language Learning beyond Japanese University Classrooms: Video Interviewing for Study Abroad

ERIC Educational Resources Information Center

Brine, John; Kaneko, Emiko; Heo, Younghyon; Vazhenin, Alexander; Bateson, Gordon

2015-01-01

In 2014, the University of Aizu was accepted for participation in Japan's national TOP Global University (TGU) initiative. In this paper, we describe our use of video interviewing to prepare Japanese students for our Global Experience Gateway study abroad TGU project. Our university specializes in computer science education at undergraduate and…

47 CFR 10.350 - CMAS Testing requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... later than the date of deployment of the CMAS, of CMAS components. (a) Required monthly tests. Testing... a required monthly test (RMT) message initiated by the Federal Alert Gateway Administrator. (2... maintenance windows. (3) A Participating CMS Provider may forego an RMT if the RMT is pre-empted by actual...

The evolution of the Danube gateway between Central and Eastern Paratethys (SE Europe): Insight from numerical modelling of the causes and effects of connectivity between basins and its expression in the sedimentary record

NASA Astrophysics Data System (ADS)

Leever, K. A.; Matenco, L.; Garcia-Castellanos, D.; Cloetingh, S. A. P. L.

2011-04-01

The Pannonian and Dacic Basins in SE Europe are presently connected by the Danube River across the South Carpathians, to which they are in a back-arc and foreland position respectively. Part of the Paratethys realm during the Neogene, open water communication between the basins was interrupted by the Late Miocene uplift of the Carpathians. Different mechanisms have been proposed for the formation of the Danube gateway: capture of the upstream lake or an upstream river or incision of an antecedent river. Estimates on its age range from Late Miocene to Quaternary. A related issue is the effect of the large Mediterranean sea level fall related to the Messinian Salinity Crisis on the Paratethys subbasins, specifically the "isolated" Pannonian Basin. In a synthetic numerical modelling study, using a pseudo-3D code integrating tectonics, surface processes and isostasy, we addressed the causes and effects of changes in connectivity between two large sedimentary basins separated by an elevated barrier. Specifically, we aimed to find the expression of connectivity events in the sedimentary record in general and the consequences for the evolution of the Pannonian-Dacic area in particular. We studied a range of parameters including the geometry and uplift rate of the barrier, downstream sea level change and lithosphere rigidity. We found that changes in connectivity are expressed in the sedimentary record through their effect on base level in the upstream basin and supply in the downstream basin. The most important factors controlling the response are the elevation difference between the basins and the upstream accommodation space at the time of reconnection. The most pronounced effect of reconnection through lake capture is predicted for a large elevation difference and limited upstream accommodation space. Downstream increase in sediment supply is dependent on the latter rather than the reconnection event itself. Of the parameters we tested, the rigidity of the lithosphere

Inventory of Data Sources Used for Watershed Condition Assessments of Fire Island National Seashore, Gateway National Recreation Area, and Sagamore Hill National Historic Site, New York and New Jersey

USGS Publications Warehouse

Benotti, Mark J.

2008-01-01

The natural resources and watershed conditions of National Park units in the New York-New Jersey area - Gateway National Recreation Area (GATE), Sagamore Hill National Historic Site (SAHI), and Fire Island National Seashore (FIIS) - are threatened by different degrees of urbanization and direct or indirect human use. Such threats as nutrient enrichment, sedimentation, exotic species invasion, water pollution, and development pose serious management concerns for these parks. Limited investigations of the status of different natural resources at or near each park have been conducted, but a comprehensive understanding of the natural resources and watershed conditions at FIIS, GATE, and SAHI is needed. This report details the sources of spatial data and metadata assembled into a Geographic Information System (GIS) for the purpose of assessing natural resources and watershed conditions at GATE, SAHI, and FIIS.

Initiation devices, initiation systems including initiation devices and related methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Daniels, Michael A.; Condit, Reston A.; Rasmussen, Nikki

Initiation devices may include at least one substrate, an initiation element positioned on a first side of the at least one substrate, and a spark gap electrically coupled to the initiation element and positioned on a second side of the at least one substrate. Initiation devices may include a plurality of substrates where at least one substrate of the plurality of substrates is electrically connected to at least one adjacent substrate of the plurality of substrates with at least one via extending through the at least one substrate. Initiation systems may include such initiation devices. Methods of igniting energetic materialsmore » include passing a current through a spark gap formed on at least one substrate of the initiation device, passing the current through at least one via formed through the at least one substrate, and passing the current through an explosive bridge wire of the initiation device.« less

Multi-Modal Traveler Information System - Gateway Interface Control Requirements

DOT National Transportation Integrated Search

1997-10-30

The Multi-Modal Traveler Information System (MMTIS) project involves a large number of Intelligent Transportation System (ITS) related tasks. It involves research of all ITS initiatives in the Gary-Chicago-Milwaukee (GCM) Corridor which are currently...

Evaluating the drug use “gateway” theory using cross-national data: Consistency and associations of the order of initiation of drug use among participants in the WHO World Mental Health Surveys*

PubMed Central

Degenhardt, Louisa; Dierker, Lisa; Chiu, Wai Tat; Medina-Mora, Maria Elena; Neumark, Yehuda; Sampson, Nancy; Alonso, Jordi; Angermeyer, Matthias; Anthony, James C.; Bruffaerts, Ronny; de Girolamo, Giovanni; de Graaf, Ron; Gureje, Oye; Karam, Aimee N.; Kostyuchenko, Stanislav; Lee, Sing; Lépine, Jean-Pierre; Levinson, Daphna; Nakamura, Yosikazu; Posada-Villa, Jose; Stein, Dan; Wells, J. Elisabeth; Kessler, Ronald C.

2010-01-01

Background It is unclear whether the normative sequence of drug use initiation, beginning with tobacco and alcohol, progressing to cannabis and then other illicit drugs, is due to causal effects of specific earlier drug use promoting progression, or to influences of other variables such as drug availability and attitudes. One way to investigate this is to see whether risk of later drug use in the sequence, conditional on use of drugs earlier in the sequence, changes according to time-space variation in use prevalence. We compared patterns and order of initiation of alcohol, tobacco, cannabis, and other illicit drug use across 17 countries with a wide range of drug use prevalence. Method Analyses used data from World Health Organization (WHO) World Mental Health (WMH) Surveys, a series of parallel community epidemiological surveys using the same instruments and field procedures carried out in 17 countries throughout the world. Results Initiation of “gateway” substances (i.e. alcohol, tobacco and cannabis) was differentially associated with subsequent onset of other illicit drug use based on background prevalence of gateway substance use. Cross-country differences in substance use prevalence also corresponded to differences in the likelihood of individuals reporting a non- normative sequence of substance initiation. Conclusion These results suggest the “gateway” pattern at least partially reflects unmeasured common causes rather than causal effects of specific drugs on subsequent use of others. This implies that successful efforts to prevent use of specific “gateway” drugs may not in themselves lead to major reductions in the use of later drugs. PMID:20060657

The retrosplenial cortex: A memory gateway between the cortical default mode network and the medial temporal lobe.

PubMed

Kaboodvand, Neda; Bäckman, Lars; Nyberg, Lars; Salami, Alireza

2018-05-01

The default mode network (DMN) involves interacting cortical areas, including the posterior cingulate cortex (PCC) and the retrosplenial cortex (RSC), and subcortical areas, including the medial temporal lobe (MTL). The degree of functional connectivity (FC) within the DMN, particularly between MTL and medial-parietal subsystems, relates to episodic memory (EM) processes. However, past resting-state studies investigating the link between posterior DMN-MTL FC and EM performance yielded inconsistent results, possibly reflecting heterogeneity in the degree of connectivity between MTL and specific cortical DMN regions. Animal work suggests that RSC has structural connections to both cortical DMN regions and MTL, and may thus serve as an intermediate layer that facilitates information transfer between cortical and subcortical DMNs. We studied 180 healthy old adults (aged 64-68 years), who underwent comprehensive assessment of EM, along with resting-state fMRI. We found greater FC between MTL and RSC than between MTL and the other cortical DMN regions (e.g., PCC), with the only significant association with EM observed for MTL-RSC FC. Mediational analysis showed that MTL-cortical DMN connectivity increased with RSC as a mediator. Further analysis using a graph-theoretical approach on DMN nodes revealed the highest betweenness centrality for RSC, confirming that a high proportion of short paths among DMN regions pass through RSC. Importantly, the degree of RSC mediation was associated with EM performance, suggesting that individuals with greater mediation have an EM advantage. These findings suggest that RSC forms a critical gateway between MTL and cortical DMN to support EM in older adults. © 2018 Wiley Periodicals, Inc.

Antarctic glaciation caused ocean circulation changes at the Eocene-Oligocene transition

NASA Astrophysics Data System (ADS)

Goldner, A.; Herold, N.; Huber, M.

2014-07-01

Two main hypotheses compete to explain global cooling and the abrupt growth of the Antarctic ice sheet across the Eocene-Oligocene transition about 34 million years ago: thermal isolation of Antarctica due to southern ocean gateway opening, and declining atmospheric CO2 (refs 5, 6). Increases in ocean thermal stratification and circulation in proxies across the Eocene-Oligocene transition have been interpreted as a unique signature of gateway opening, but at present both mechanisms remain possible. Here, using a coupled ocean-atmosphere model, we show that the rise of Antarctic glaciation, rather than altered palaeogeography, is best able to explain the observed oceanographic changes. We find that growth of the Antarctic ice sheet caused enhanced northward transport of Antarctic intermediate water and invigorated the formation of Antarctic bottom water, fundamentally reorganizing ocean circulation. Conversely, gateway openings had much less impact on ocean thermal stratification and circulation. Our results support available evidence that CO2 drawdown--not gateway opening--caused Antarctic ice sheet growth, and further show that these feedbacks in turn altered ocean circulation. The precise timing and rate of glaciation, and thus its impacts on ocean circulation, reflect the balance between potentially positive feedbacks (increases in sea ice extent and enhanced primary productivity) and negative feedbacks (stronger southward heat transport and localized high-latitude warming). The Antarctic ice sheet had a complex, dynamic role in ocean circulation and heat fluxes during its initiation, and these processes are likely to operate in the future.

Antarctic glaciation caused ocean circulation changes at the Eocene-Oligocene transition.

PubMed

Goldner, A; Herold, N; Huber, M

2014-07-31

Two main hypotheses compete to explain global cooling and the abrupt growth of the Antarctic ice sheet across the Eocene-Oligocene transition about 34 million years ago: thermal isolation of Antarctica due to southern ocean gateway opening, and declining atmospheric CO2 (refs 5, 6). Increases in ocean thermal stratification and circulation in proxies across the Eocene-Oligocene transition have been interpreted as a unique signature of gateway opening, but at present both mechanisms remain possible. Here, using a coupled ocean-atmosphere model, we show that the rise of Antarctic glaciation, rather than altered palaeogeography, is best able to explain the observed oceanographic changes. We find that growth of the Antarctic ice sheet caused enhanced northward transport of Antarctic intermediate water and invigorated the formation of Antarctic bottom water, fundamentally reorganizing ocean circulation. Conversely, gateway openings had much less impact on ocean thermal stratification and circulation. Our results support available evidence that CO2 drawdown--not gateway opening--caused Antarctic ice sheet growth, and further show that these feedbacks in turn altered ocean circulation. The precise timing and rate of glaciation, and thus its impacts on ocean circulation, reflect the balance between potentially positive feedbacks (increases in sea ice extent and enhanced primary productivity) and negative feedbacks (stronger southward heat transport and localized high-latitude warming). The Antarctic ice sheet had a complex, dynamic role in ocean circulation and heat fluxes during its initiation, and these processes are likely to operate in the future.

75 FR 42071 - Taking and Importing Marine Mammals; Operations of a Liquified Natural Gas Port Facility in...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-20

... was also published in the Federal Register for the proposed IHA for Northeast Gateway's LNG Port... Gateway Energy Bridge\\TM\\ L.L.C. (Northeast Gateway or NEG) and its partner, Algonquin Gas Transmission... its proposal to issue an authorization to Northeast Gateway and Algonquin to incidentally take, by...

Policies and Practices regarding Students with Accents in Speech-Language Pathology Training Programs

ERIC Educational Resources Information Center

Levy, Erika S.; Crowley, Catherine J.

2012-01-01

Speech-language pathology (SLP) training programs are the initial gateway for nonnative speakers of English to join the SLP profession. An anonymous web-based survey in New York State examined policies and practices implemented when SLP students have foreign accents in English or in other languages. Responses were elicited from 530 students and 28…

Comparison of Propulsion Options for Human Exploration of Mars

NASA Technical Reports Server (NTRS)

Drake, Bret G.; McGuire, Melissa L.; McCarty, Steven L.

2018-01-01

NASA continues to advance plans to extend human presence beyond low-Earth orbit leading to human exploration of Mars. The plans being laid out follow an incremental path, beginning with initial flight tests followed by deployment of a Deep Space Gateway (DSG) in cislunar space. This Gateway, will serve as the initial transportation node for departing and returning Mars spacecraft. Human exploration of Mars represents the next leap for humankind because it will require leaving Earth on a long mission with very limited return, rescue, or resupply capabilities. Although Mars missions are long, approaches and technologies are desired which can reduce the time that the crew is away from Earth. This paper builds off past analyses of NASA's exploration strategy by providing more detail on the performance of alternative in-space transportation options with an emphasis on reducing total mission duration. Key options discussed include advanced chemical, nuclear thermal, nuclear electric, solar electric, as well as an emerging hybrid propulsion system which utilizes a combination of both solar electric and chemical propulsion.

Agreement between Medline searches using the Medline-CD-Rom and Internet Pubmed, BioMedNet, Medscape and Gateway search-engines.

PubMed

Caro-Rojas, Rosa Angela; Eslava-Schmalbach, Javier H

2005-01-01

To compare the information obtained from the Medline database using Internet commercial search engines with that obtained from a compact disc (Medline-CD). An agreement study was carried out based on 101 clinical scenarios provided by specialists in internal medicine, pharmacy, gynaecology-obstetrics, surgery and paediatrics. 175 search strategies were employed using the connector AND plus text within quotation marks. The search was limited to 1991-1999. Internet search-engines were selected by common criteria. Identical search strategies were independently applied to and masked from Internet search engines, as well as the Medline-CD. 3,488 articles were obtained using 129 search strategies. Agreement with the Medline-CD was 54% for PubMed, 57% for Gateway, 54% for Medscape and 65% for BioMedNet. The highest agreement rate for a given speciality (paediatrics) was 78.1% for BioMedNet, having greater -/- than +/+ agreement. Even though free access to Medline has encouraged the boom and growth of evidence-based medicine, these results must be considered within the context of which search engine was selected for doing the searches. The Internet search engines studied showed a poor agreement with the Medline-CD, the rate of agreement differing according to speciality, thus significantly affecting searches and their reproducibility. Software designed for conducting Medline database searches, including the Medline-CD, must be standardised and validated.

Demonstration Assessment of Light-Emitting Diode (LED) Roadway Lighting, I-35W Bridge, Minneapolis, Minnesota, Phase I Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kinzey, B. R.; Myer, M. A.

2009-08-01

On the I-35W Bridge in Minneapolis, Minnesota, the GATEWAY program conducted a two-phase demonstration of LED roadway lighting on the main span, which is one of the country's oldest continuously operated exterior LED lighting installations. The Phase I report provides an overview of initial project results including lighting performance, economic performance, and potential energy savings.

Annual Report: Carbon Capture Simulation Initiative (CCSI) (30 September 2013)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, David C.; Syamlal, Madhava; Cottrell, Roger

2013-09-30

, West Virginia University, Boston University and the University of Texas at Austin) bring unparalleled expertise in multiphase flow reactors, combustion, process synthesis and optimization, planning and scheduling, and process control techniques for energy processes. During Fiscal Year (FY) 13, CCSI announced the initial release of its first set of computational tools and models during the October 2012 meeting of its Industry Advisory Board. This initial release led to five companies licensing the CCSI Toolset under a Test and Evaluation Agreement this year. By the end of FY13, the CCSI Technical Team had completed development of an updated suite of computational tools and models. The list below summarizes the new and enhanced toolset components that were released following comprehensive testing during October 2013. 1. FOQUS. Framework for Optimization and Quantification of Uncertainty and Sensitivity. Package includes: FOQUS Graphic User Interface (GUI), simulation-based optimization engine, Turbine Client, and heat integration capabilities. There is also an updated simulation interface and new configuration GUI for connecting Aspen Plus or Aspen Custom Modeler (ACM) simulations to FOQUS and the Turbine Science Gateway. 2. A new MFIX-based Computational Fluid Dynamics (CFD) model to predict particle attrition. 3. A new dynamic reduced model (RM) builder, which generates computationally efficient RMs of the behavior of a dynamic system. 4. A completely re-written version of the algebraic surrogate model builder for optimization (ALAMO). The new version is several orders of magnitude faster than the initial release and eliminates the MATLAB dependency. 5. A new suite of high resolution filtered models for the hydrodynamics associated with horizontal cylindrical objects in a flow path. 6. The new Turbine Science Gateway (Cluster), which supports FOQUS for running multiple simulations for optimization or UQ using a local computer or cluster. 7. A new statistical tool (BSS

Windward Passage and Jamaica Channel: New Insights About two Tectonic Gateways of the Northern Caribbean

NASA Astrophysics Data System (ADS)

Cormier, M. H.; Blake, R. E.; Coleman, D. F.; Guerrier, K.; Raineault, N.; Saintilus, N.; Walker, S. L.; Auscavitch, S.; Wagner, J.

2014-12-01

This August 2014, a 14-day expedition of the E/V NAUTILUS of the OCEAN EXPLORATION TRUST will explore the region delimited by two deep straits of the northern Caribbean, the Windward passage and the Jamaica Channel. The morphology of these straits is controlled by two transform faults: The Septentrional fault, which stretches between Cuba and Haiti (slip rate: ~13 mm/yr), and the Enriquillo-Plantain Garden Fault (EPGF), which stretches between Jamaica and Haiti (slip rate: ~9 mm/yr). Together, these faults bound the Gonave microplate, an elongated platelet caught between the North America plate and Caribbean plates. The Septentrional fault ruptured in 1842, devastating the town of Cap Haitien. The EPGF ruptured catastrophically in 2010 near Port-au-Prince (death toll > 100,000). Tsunamis were associated with both earthquakes. Oblique slip on these two faults is presumably controlling the history of uplift and subsidence of the seafloor, and has therefore also been regulating the water exchanges between the north central Atlantic and the Caribbean Sea. New multibeam bathymetric and CHIRP sub-bottom profiling data will be acquired with the E/V NAUTILUS, while the ROV HERCULES will be used to collect video, water and rock samples, as well as water column physical properties. We anticipate that this survey will document the following: (1) The nature of drowned carbonate platforms, which in turn may provide useful markers to assess rates of vertical deformation along the two faults. (2) The extent of major landslides detected on the steep fore reefs from existing multibeam bathymetric data. (3) Whether fluids are actively seeping along the fault traces or in association with the landslides, as has been reported elsewhere around the World. (4) If cold seeps are indeed present, to what extent their associated ecosystems are affected by the bottom currents that flow through these gateways. Altogether, the new findings should contribute to a better understanding of the

Risky business: a longitudinal study examining cigarette smoking initiation among susceptible and non-susceptible e-cigarette users in Canada

PubMed Central

Aleyan, Sarah; Cole, Adam; Qian, Wei; Leatherdale, Scott T

2018-01-01

Objectives Given that many adolescent e-cigarette users are never-smokers, the possibility that e-cigarettes may act as a gateway to future cigarette smoking has been discussed in various studies. Longitudinal data are needed to explore the pathway between e-cigarette and cigarette use, particularly among different risk groups including susceptible and non-susceptible never-smokers. The objective of this study was to examine whether baseline use of e-cigarettes among a sample of never-smoking youth predicted cigarette smoking initiation over a 2-year period. Design Longitudinal cohort study. Setting 89 high schools across Ontario and Alberta, Canada. Participants A sample of grade 9–11 never-smoking students at baseline (n=9501) who participated in the COMPASS study over 2 years. Primary and secondary outcome measures Participants completed in-class questionnaires that assessed smoking susceptibility and smoking initiation. Results Among the baseline sample of non-susceptible never-smokers, 45.2% of current e-cigarette users reported trying a cigarette after 2 years compared with 13.5% of non-current e-cigarette users. Among the baseline sample of susceptible never-smokers, 62.4% of current e-cigarette users reported trying a cigarette after 2 years compared with 36.1% of non-current e-cigarette users. Overall, current e-cigarette users were more likely to try a cigarette 2 years later. This association was stronger among the sample of non-susceptible never-smokers (AOR=5.28, 95% CI 2.81 to 9.94; p<0.0001) compared with susceptible never-smokers (AOR=2.78, 95% CI 1.84 to 4.20; p<0.0001). Conclusions Findings from this large, longitudinal study support public health concerns that e-cigarette use may contribute to the development of a new population of cigarette smokers. They also support the notion that e-cigarettes are expanding the tobacco market by attracting low-risk youth who would otherwise be unlikely to initiate using cigarettes. Careful

Draft material : enhanced freight movement at domestic and international gateways

DOT National Transportation Integrated Search

1997-07-01

The purpose of this report is to provide a framework for integrating the core program activities that constitute the National Science and Technology Councils (NSTCs) public-private initiative to improve freight movement at domestic and internat...

47 CFR 10.10 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... this part. (g) “C” Interface. The interface between the Alert Gateway and CMS provider Gateway. (h) CMS provider Gateway. The mechanism(s) that supports the “C” interface and associated protocols between the...

Kennedy Space Center - "America's Gateway to Space"

NASA Technical Reports Server (NTRS)

Petro, Janet; Chevalier, Mary Ann; Hurst, Chery

2011-01-01

KSC fits into the overall NASA vision and mission by moving forward so that what we do and learn will benefit all here on Earth. In January of last year, KSC revised its Mission and Vision statements to articulate our identity as we align with this new direction the Agency is heading. Currently KSC is endeavoring to form partnerships with industry, , Government, and academia, utilizing institutional assets and technical capabilities to support current and future m!issions. With a goal of safe, low-cost, and readily available access to space, KSC seeks to leverage emerging industries to initiate development of a new space launch system, oversee the development of a multipurpose crew vehicle, and assist with the efficient and timely evolution of commercial crew transportation capabilities. At the same time, KSC is pursuing modernizing the Center's infrastructure and creating a multi-user launch complex with increased onsite processing and integration capabilities.

Timing of Indonesian Gateway Restriction Between 4.0 and 2.8 Ma and its Impact on Indian Ocean Surface Waters Based on Calcareous Nannoplankton Assemblages

NASA Astrophysics Data System (ADS)

Auer, G.; De Vleeschouwer, D.; Groeneveld, J.; Bogus, K.; Henderiks, J.; Castañeda, I. S.; Expedition 356 Scientists, I.

2017-12-01

The Early Pliocene is characterized by a fundamental reorganization of Earth's climate. In particular, the ongoing constriction of the Indonesian Gateway (IG) around 4.0 - 3.0 Ma is commonly evoked cause for these climatic changes (Christensen et al., 2017; De Schepper et al., 2014; Karas et al., 2009; 2017). The constriction of the IG, caused by the northward movement of Australia and related uplift of Indonesia, had major effects on global climate and may have contributed to Northern Hemisphere cooling via complex atmospheric and oceanographic teleconnections. Untangling the exact timing of IG constriction is thus critical for resolving the mechanisms driving Earth's climatic evolution during the Pliocene. Here we present high-resolution reconstructions of surface water conditions and IG connectivity using calcareous nannoplankton (CNP) assemblages between 4.0 and 2.8 Ma at Site U1463 (18°59'S, 117°37'E; IODP Expedition 356). Located on the Northwest Shelf (NWS) of Australia, the site lies directly in the path of the upper branch of the Leeuwin-Holloway current, making it an ideal location to study Pliocene IG dynamics and their influence on the eastern Indian Ocean. Using modern analogue based interpretation of CNP assemblages, in combination with an independent orbitally tuned age model, shows a change in surface water conditions along the NWS 3.8 Ma recognizable by a decrease in tropical taxa like Umbilicosphaera sibogae and Sphenolithus spp. Subsequently, a shift from Gephyrocapsa sp. to Reticulofenestra sp. dominated CNP assemblages and the increase of mesotrophic CNP taxa (e.g. Umbilicosphaera jafari; Helicosphaera spp.), suggests that warm, stratified, oligotrophic (i.e. tropical) waters were replaced by cooler, more turbulent, and less saline waters by 3.8 - 3.6 Ma. We relate this switch in dominant water masses to changes in IG geometry delivering relatively cooler and fresher waters from northern Pacific sources to the NWS. The abundance of