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Sample records for general population relation

  1. Are Autistic Traits in the General Population Related to Global and Regional Brain Differences?

    ERIC Educational Resources Information Center

    Koolschijn, P. Cédric M. P.; Geurts, Hilde M.; van der Leij, Andries R.; Scholte, H. Steven

    2015-01-01

    There is accumulating evidence that autistic-related traits in the general population lie on a continuum, with autism spectrum disorders representing the extreme end of this distribution. Here, we tested the hypothesis of a possible relationship between autistic traits and brain morphometry in the general population. Participants completed the…

  2. Time orientation and health-related behaviour: Measurement in general population samples

    PubMed Central

    Crockett, Rachel A.; Weinman, John; Hankins, Matthew; Marteau, Theresa

    2009-01-01

    Research on health behaviour and time orientation has been hindered by a lack of consensus about appropriate measurement. Study 1 assessed the reliability of the Consideration of Future Consequences Scale (CFC) and the Zimbardo Time Perspective Inventory (ZTPI) in a general population sample (n = 300). Although more reliable, the CFC was less readable. Study 2 assessed the validity of a shortened ZTPI, measuring future and present orientation, and the full CFC. The measures had good discrimination to distinguish interpersonal differences. Construct validity of present, but not future, orientation as measured by the ZTPI, was evidenced by its mediation of the association between socioeconomic status and expectations of participating in diabetes screening. The CFC mediated this relationship more weakly. Further investigation of present orientation in understanding health-related behaviour is warranted. PMID:20204997

  3. Eating and body attitudes related to noncompetitive bodybuilding in military and general Hungarian male student populations.

    PubMed

    Lukács, Liza; Murányi, István; Túry, Ferenc

    2007-02-01

    Pathological eating attitudes and extreme weight control practices occur most commonly in certain female populations. In some young male occupation groups, such as in the armed forces, the appearance of physical strength and muscularity has particular importance. We studied body and eating attitudes and the prevalence of bodybuilding and steroid abuse in 480 military college and 752 general college male students. The Eating Disorder Inventory was used for all subjects. General college students had higher body mass index values than did military students. The prevalence of bodybuilding and steroid abuse was significantly greater in the military population. Comparisons between the study groups and within groups showed significantly different scores on certain Eating Disorder Inventory subscales. The study revealed that male military college students have some protective factors against the psychopathological features of eating disorders.

  4. The Relation of Moderate Alcohol Consumption to Hyperuricemia in a Rural General Population

    PubMed Central

    Li, Zhao; Guo, Xiaofan; Liu, Yamin; Chang, Ye; Sun, Yingxian; Zhu, Guangshuo; Abraham, Maria Roselle

    2016-01-01

    Background: although alcohol abuse is known to increase serum uric acid, the relation between moderate drinking and uric acid have remained poorly understood. We performed this study to evaluate whether different alcohol consumption level has different effects on the risk of hyperuricemia based on a rural general population. Method: multi-stage cluster sampling method was used to select a representative sample of individuals aged 35 years or older. Participants were asked to provide information about their alcohol consumption. Data regarding the demographic and lifestyle characteristics and the blood biochemical indexes of these participants were collected by well-trained personnel. Results: in total, 11,039 participants aged 35 years or older were included (4997 men and 6042 women). The prevalence of hyperuricemia in the different male alcohol consumption groups was 11.9% in non-drinkers, 12.6% in moderate drinkers, and 16.3% in heavy drinkers (p < 0.001). In females, the rates were 6.3% in non-drinkers, 8.1% in moderate drinkers, and 6.6% for heavy drinkers (p = 0.818). In males, multivariate logistic regression analyses shows heavy drinkers had an approximately 1.7-fold higher risk of hyperuricemia (OR: 1.657, 95% CI: 1.368 to 2.007, p < 0.001) than non-drinkers; moderate drinkers did not experience a significant increase in risk (OR: 1.232, 95% CI: 0.951 to 1.596, p = 0.114)). Multivariate logistic regression analyses of females showed that, compared with non-drinkers, neither moderate nor heavy drinkers had a significantly increased risk of hyperuricemia (OR: 1.565, 95% CI: 0.521 to 4.695, p = 0.425 for heavy drinkers; OR: 0.897, 95% CI: 0.117 to 6.855, p = 0.916 for moderate drinkers). Conclusions: heavy alcohol consumption increased the risk of hyperuricemia for males but not for females. Among both males and females, moderate alcohol consumption did not increase the risk of hyperuricemia. PMID:27447659

  5. Heart Rate Variability and Sleep-Related Breathing Disorders in the General Population.

    PubMed

    Aeschbacher, Stefanie; Bossard, Matthias; Schoen, Tobias; Schmidlin, Delia; Muff, Christoph; Maseli, Anna; Leuppi, Jörg D; Miedinger, David; Probst-Hensch, Nicole M; Schmidt-Trucksäss, Arno; Risch, Martin; Risch, Lorenz; Conen, David

    2016-09-15

    Obstructive sleep apnea seems to have an important influence on the autonomic nervous system. In this study, we assessed the relations of sleep apnea-related parameters with 24-hour heart rate variability (HRV) in a large population of young and healthy adults. Participants aged 25 to 41 years with a body mass index <35 kg/m(2) and without known obstructive sleep apnea were included in a prospective population-based cohort study. HRV was assessed using 24-hour electrocardiographic monitoring. The SD of all normal RR intervals (SDNN) was used as the main HRV variable. Apnea-Hypopnea Index (AHI) and oxygen desaturation index (ODI) were obtained from nighttime pulse oximetry with nasal airflow measurements. We defined sleep-related breathing disorders as an AHI ≥5 or an ODI ≥5. Multivariable regression models were constructed to assess the relation of HRV with either AHI or ODI. Median age of the 1,255 participants was 37 years, 47% were men, and 9.6% had an AHI ≥5. Linear inverse associations of SDNN across AHI and ODI groups were found (p for trend = 0.006 and 0.0004, respectively). The β coefficients (95% CI) for the relation between SDNN and elevated AHI were -0.20 (-0.40 to -0.11), p = 0.04 and -0.29 (-0.47 to -0.11), p = 0.002 for elevated ODI. After adjustment for 24-hour heart rate, the same β coefficients (95% CI) were -0.06 (-0.22 to 0.11), p = 0.51 and -0.14 (-0.30 to 0.01), p = 0.07, respectively. In conclusion, even early stages of sleep-related breathing disorders are inversely associated with HRV in young and healthy adults, suggesting that they are tightly linked with autonomic dysfunction. However, HRV and 24-hour heart rate seem to have common information. PMID:27553103

  6. Sleep Hygiene Pattern and Behaviors and Related Factors among General Population in West Of Iran

    PubMed Central

    Khazaie, Habibolah; Chehri, Azita; Sadeghi, Kheirollah; Heydarpour, Fatemeh; Soleimani, Akram; Rezaei, Zahra

    2016-01-01

    Introduction: Sleep hygiene was found as an important predictor for sleep quality. People’s sleep hygiene can have a major role in their daily function. The purpose of the study was to determine sleep hygiene patterns and sleep hygiene behaviors and factors affecting them in the general population of Kermanshah, Iran. Material and methods: In this cross-sectional study, 1829 men and 1262 women were selected randomly from 50 clusters of different parts of the city. The inclusion criteria were age between 12 and 65 years and living in Kermanshah. The exclusion criteria were psychiatric disorder and known general medical conditions that affecting sleep. The data collection instruments were demographic questionnaire and Sleep Hygiene Questionnaire, consisted of 13 items about biological rhythm and bed room environment and behaviors that affecting sleep. Data were analyzed by using SPSS version 16 software. Results: The highest percentage was obtained for irregular woke and went up from day to day or at weekend and holidays (74.8%). Only 213 (6.9%) participants were classified as having good sleep hygiene (score 12-14). The mean age of very poor, poor, moderate, and good sleepers was 34.8 ± 14.4, 33.7 ± 17.4, 36.5 ± 13.8, and 35 ± 13.7years, respectively. There were significant differences between the age of poor and moderate sleepers and also sleep hygiene patterns with respect to sex, education level and job. Conclusion: Poor sleep hygiene were more frequent in Iranian peoples and the major problem in sleep hygiene in our study was inappropriate sleep schedule. PMID:27045403

  7. Health-Related Quality of Life among Artisanal Fisherwomen/Shellfish Gatherers: Lower than the General Population

    PubMed Central

    Müller, Juliana dos Santos; Falcão, Ila Rocha; Couto, Maria Carolina Barreto Moreira; Viana, Wendel da Silva; Alves, Ivone Batista; Viola, Denise Nunes; Woods, Courtney Georgette; Rêgo, Rita Franco

    2016-01-01

    Quality of life is an indicator of how well one perceives that he/she is functioning physically and mentally. The aim of this paper is to determine the health-related quality of life (HRQOL) of artisanal fisherwomen/shellfish gatherers from the Saubara municipality in Bahia, Brazil in comparison to the general population. A structured questionnaire was administered to a sample of 209 artisanal fisherwomen selected at random. The HRQOL questionnaire, known as the 36-Item Short-Form Health Survey version 1 (SF-36v01), was also used, having been translated and verified cross-culturally for the Brazilian population. Sociodemographic, lifestyle and comorbidity information was also collected. Chronic diseases and indicators of musculoskeletal disorders (MSDs) were self-reported. The study population consisted primarily of individuals between 30 and 45 years of age (78%), of self-classified races black or brown (96.2%), with no more than an elementary school education (77%) and married (64.6%). In all the SF-36v01 dimensions, the values in the sample were lower than in the general population of Brazil, which was used as the reference population. In the “Physical Health” domain (Physical Functioning; Physical Role Limitations; Bodily Pain; General Health Perception) a tendency toward a lower health-related quality of life was observed among those who were older, had a lower education level, and had a prevalence of MSDs, hypertension or arthritis. The interference of health conditions linked to the fisherwomen’s work activities may contribute to lower HRQOL in all analyzed aspects, in comparison to the general population. In light of these findings, public health policies must consider these informal workers who contribute greatly to Brazil’s economy and food system. PMID:27164118

  8. Health-Related Quality of Life among Artisanal Fisherwomen/Shellfish Gatherers: Lower than the General Population.

    PubMed

    Müller, Juliana Dos Santos; Falcão, Ila Rocha; Couto, Maria Carolina Barreto Moreira; Viana, Wendel da Silva; Alves, Ivone Batista; Viola, Denise Nunes; Woods, Courtney Georgette; Rêgo, Rita Franco

    2016-01-01

    Quality of life is an indicator of how well one perceives that he/she is functioning physically and mentally. The aim of this paper is to determine the health-related quality of life (HRQOL) of artisanal fisherwomen/shellfish gatherers from the Saubara municipality in Bahia, Brazil in comparison to the general population. A structured questionnaire was administered to a sample of 209 artisanal fisherwomen selected at random. The HRQOL questionnaire, known as the 36-Item Short-Form Health Survey version 1 (SF-36v01), was also used, having been translated and verified cross-culturally for the Brazilian population. Sociodemographic, lifestyle and comorbidity information was also collected. Chronic diseases and indicators of musculoskeletal disorders (MSDs) were self-reported. The study population consisted primarily of individuals between 30 and 45 years of age (78%), of self-classified races black or brown (96.2%), with no more than an elementary school education (77%) and married (64.6%). In all the SF-36v01 dimensions, the values in the sample were lower than in the general population of Brazil, which was used as the reference population. In the "Physical Health" domain (Physical Functioning; Physical Role Limitations; Bodily Pain; General Health Perception) a tendency toward a lower health-related quality of life was observed among those who were older, had a lower education level, and had a prevalence of MSDs, hypertension or arthritis. The interference of health conditions linked to the fisherwomen's work activities may contribute to lower HRQOL in all analyzed aspects, in comparison to the general population. In light of these findings, public health policies must consider these informal workers who contribute greatly to Brazil's economy and food system. PMID:27164118

  9. School-Related Stress, School Support, and Somatic Complaints: A General Population Study.

    ERIC Educational Resources Information Center

    Torsheim, Torbjorn; Wold, Bente

    2001-01-01

    Examined relationship between school-related stress, social support, and somatic complaints among Norwegian adolescents. Found that students with high levels of school-related stress had a higher odds ratio for weekly headache, abdominal pain, backache, dizziness, and coexisting somatic complaints. For social support, associations were weaker, but…

  10. Internet and Social Media For Health-Related Information and Communication in Health Care: Preferences of the Dutch General Population

    PubMed Central

    Engelen, Lucien JLPG; Berben, Sivera AA; Teerenstra, Steven; Samsom, Melvin; Schoonhoven, Lisette

    2013-01-01

    Background Health care is increasingly featured by the use of Web 2.0 communication and collaborative technologies that are reshaping the way patients and professionals interact. These technologies or tools can be used for a variety of purposes: to instantly debate issues, discover news, analyze research, network with peers, crowd-source information, seek support, and provide advice. Not all tools are implemented successfully; in many cases, the nonusage attrition rates are high. Little is known about the preferences of the Dutch general population regarding the use of the Internet and social media in health care. Objective To determine the preferences of the general population in the Netherlands regarding the use of the Internet and social media in health care. Methods A cross-sectional survey was disseminated via a popular Dutch online social network. Respondents were asked where they searched for health-related information, how they qualified the value of different sources, and their preferences regarding online communication with health care providers. Results were weighed for the Dutch population based on gender, age, and level of education using official statistics. Numbers and percentages or means and standard deviations were presented for different subgroups. One-way ANOVA was used to test for statistical differences. Results The survey was completed by 635 respondents. The Internet was found to be the number one source for health-related information (82.7%), closely followed by information provided by health care professionals (71.1%). Approximately one-third (32.3%) of the Dutch population search for ratings of health care providers. The most popular information topics were side effects of medication (62.5%) and symptoms (59.7%). Approximately one-quarter of the Dutch population prefer to communicate with a health care provider via social media (25.4%), and 21.2% would like to communicate via a webcam. Conclusions The Internet is the main source of health-related

  11. How Is Emotional Awareness Related to Emotion Regulation Strategies and Self-Reported Negative Affect in the General Population?

    PubMed Central

    Subic-Wrana, Claudia; Beutel, Manfred E.; Brähler, Elmar; Stöbel-Richter, Yve; Knebel, Achim; Lane, Richard D.; Wiltink, Jörg

    2014-01-01

    Objective The Levels of Emotional Awareness Scale (LEAS) as a performance task discriminates between implicit or subconscious and explicit or conscious levels of emotional awareness. An impaired awareness of one's feeling states may influence emotion regulation strategies and self-reports of negative emotions. To determine this influence, we applied the LEAS and self-report measures for emotion regulation strategies and negative affect in a representative sample of the German general population. Sample and Methods A short version of the LEAS, the Hospital Anxiety and Depression Scale (HADS) and the Emotion Regulation Questionnaire (ERQ), assessing reappraisal and suppression as emotion regulation strategies, were presented to N = 2524 participants of a representative German community study. The questionnaire data were analyzed with regard to the level of emotional awareness. Results LEAS scores were independent from depression, but related to self-reported anxiety. Although of small or medium effect size, different correlational patters between emotion regulation strategies and negative affectivity were related to implict and explict levels of emotional awareness. In participants with implicit emotional awareness, suppression was related to higher anxiety and depression, whereas in participants with explicit emotional awareness, in addition to a positive relationship of suppression and depression, we found a negative relationship of reappraisal to depression. These findings were independent of age. In women high use of suppression and little use of reappraisal were more strongly related to negative affect than in men. Discussion Our first findings suggest that conscious awareness of emotions may be a precondition for the use of reappraisal as an adaptive emotion regulation strategy. They encourage further research in the relation between subconsious and conscious emotional awareness and the prefarance of adaptive or maladaptive emotion regulation strategies The

  12. Environmental, occupational, and personal factors related to the prevalence of sick building syndrome in the general population.

    PubMed Central

    Norbäck, D; Edling, C

    1991-01-01

    Possible relations between prevalence of sick building syndrome (SBS) and environmental, occupational, and personal factors were studied in a random sample (0.1%) of the general population aged 20-65 in a three county region in middle Sweden. Childhood exposure to environmental tobacco smoke from smoking mothers and a childhood in urban areas was related to SBS symptoms. Current urban residency, fresh paint, and preschool children in the dwelling were also related to symptoms. Other residential factors such as age of building, type of building, degree of crowding, mechanical ventilation, or signs of moisture or mould growth were not related to symptoms. Other factors related to symptoms were history of atopy, allergy to nickel, proneness to infection, hyperreactivity, static electricity, work with video display units (VDU), work satisfaction, and climate of cooperation at work. Age, sex, marital state, education level, work stress, obesity, current or earlier smoking, regular physical exercise, or occupational exposure to chemicals did not correlate with symptoms. Women had a higher proportion of symptoms than men but these differences were not significant when adjusting for differences in allergy to nickel, hyperreactivity, and proneness to infection. Maternal smoking was related to a twofold increase of both atopy and allergy to nickel in the adult offspring. Eye symptoms were most common in administrative, managerial, and service work. Airway symptoms were most common in transport and communication work. Dermal symptoms were most common in professional and technical and related work. General symptoms were most common in service, health, hospital, and social work. The lowest prevalence of symptoms was found in agricultural, forestry, and sales work. Women and subjects allergic to nickel worked more often in occupations without exposure to chemicals, but no evidence was found for selection mechanisms causing sensitive persons to move from exposed to unexposed

  13. Relationship between masculinity and feminity in drinking in alcohol-related behavior in a general population sample.

    PubMed

    Lara-Cantú, M A; Medina-Mora, M E; Gutiérrez, C E

    1990-08-01

    The relationship between gender-related personality traits, on one hand and drinking, permissiveness towards drinking, and social as well as personal problems associated to drinking on the other, was studied in a general population sample from the City of Morelia, Mexico. Four gender-related traits scales were used for measuring assertive and aggressive masculinity and affective and submissive feminity, in addition to a standardized questionnaire for assessing drinking and other associated behavior. Some of the main results showed that people with high scores in affective feminity were less willing to allow drinking. Men who adopted a submissive feminine role and women with high masculine aggressive scores were more permissive as regards drinking. Among men, assertive masculine and affective feminine traits were more characteristic among those who drank than among abtainers. Drinking among women was related to liberal attitudes towards drinking and to aggressive masculinity. As regards the number of drinks consumed per month, assertive masculinity and liberal attitudes among men and affective feminity and liberal attitudes among women predicted the number of drinks. Affective feminity was negatively related to drinking. Regarding drinking-associated problems, frequency of drunkenness and submissive feminity among males predicted greater personal and social problems. Among women, drunkenness frequency and number of drinks were the most significant predictors. Contrary to what has been found in other countries, gender was a better drinking predictor than gender-related personality traits.

  14. Migraine life-time prevalence in mental disorders: concurrent comparisons with first-degree relatives and the general population.

    PubMed

    Baptista, Trino; Uzcátegui, Euderruh; Arapé, Yinet; Serrano, Ana; Mazzarella, Xiorella; Quiroz, Segundo; Ramirez, Clara Isabel; Padrón de Freytez, Alix

    2012-03-01

    The authors quantified the prevalence of migraine in subjects with mental disorders, first-degree relatives and the adult general population (GP) in Mérida, Venezuela. After validation, a modified, short version of the Lipton's diagnostic scale was administered to consecutively admitted in- and out-patients (n = 1059), their first-degree relatives (n = 445) and a probabilistic sample of the GP (n = 516). In the GP, the frequency of migraine (percentage and 95% confidence interval) was 14.9 (11.8-17.9). The migraine frequencies were (percentage and odd ratio probability against the GP: bipolar disorder (15.7%, p = 0.5), schizophrenia (8.3%, p = 0.08), depression and dysthimia (24.4%, p = 0.2), anxiety disorders (10.0%, p = 0.02), personality disorders (11.4%, p = 0.15), all other disorders (15.5%, p = 0.4), relatives of bipolar patients (4.4%, p < 0.001), relatives of schizophrenia patients (3.5%, p = 0.003), and relatives of patients with all other mental disorders (12.8%, p = 0.4). Migraine was more common in women (p < 0.001), and the bipolar patients presented the highest female to male ratio (8:1). A high variability was observed in migraine prevalence among the diagnostic categories, but it was particularly high in subjects with affective disorders, mainly in women, who thus deserve special attention from clinicians.

  15. After plastic surgery: adolescent-reported appearance ratings and appearance-related burdens in patient and general population groups.

    PubMed

    Simis, Kuni J; Hovius, Steven E R; de Beaufort, Inez D; Verhulst, Frank C; Koot, Hans M

    2002-01-01

    The aim of this study was to determine the effects of appearance-related surgery on psychosocial functioning during adolescence. To this end, changes in bodily attitudes and appearance-related burdens in adolescents undergoing corrective (for aesthetic deformities) and reconstructive (for congenital or acquired deformities) surgery were compared with those in a general population sample.A group of 184 adolescent plastic surgery patients (corrective, n = 100; reconstructive, n = 84), and a comparison group of 83 adolescents at random selected from three municipalities (corrective, n = 67; reconstructive, n = 16), aged 12 to 22 years, were studied at two time points with a 6-month interval. The plastic surgical patients were studied presurgically and postsurgically. Using fully structured telephone interviews and postal questionnaires, adolescents' ratings of their appearance, bodily satisfaction and attitudes, and appearance-related burdens were obtained. All patients reported a significant decrease in burdens after surgery compared with the comparison group, indicating a much more prominent improvement in the patient sample compared with the developmental changes that may be expected to occur in adolescence. The corrective patient group reported least burdens after the operation. More specifically, the "breasts" group benefited most from the operation, indicating that breast corrections are rewarding interventions. The findings of this study imply that adolescents can be regarded as good candidates for plastic surgery. They gain bodily satisfaction, and they are relieved of many appearance-related burdens. Physical, social, and psychological burdens related to appearance satisfaction improve considerably in both corrective and reconstructive adolescent patients.

  16. A "suicide pill" for older people: attitudes of physicians, the general population, and relatives of patients who died after euthanasia or physician-assisted suicide in The Netherlands.

    PubMed

    Rurup, Mette L; Onwuteaka-Philipsen, Bregje D; Van Der Wal, Gerrit

    2005-01-01

    In the Netherlands there has been ongoing debate in the past 10 years about the availability of a hypothetical "suicide pill", with which older people could end their life in a dignified way if they so wished. Data on attitudes to the suicide pill were collected in the Netherlands from 410 physicians, 1,379 members of the general population, and 87 relatives of patients who died after euthanasia or physician-assisted suicide. The general population and relatives were more in favor than physicians. Fifteen percent of the general population and 36% of the relatives thought a suicide pill should be made available.

  17. Use of antacids in a general population: the impact of health-related variables, lifestyle and sociodemographic characteristics.

    PubMed

    Furu, K; Straume, B

    1999-06-01

    Self-medication with antacids is very common in patients with less severe forms of dyspepsia, but we know very little about the users of antacids and their incentive to take them. The aim of this study was to analyze the relationship between self-reported use of antacids and health-related variables, lifestyle, and sociodemographic characteristics in order to characterize the use of antacids in a general population. The use of antacids was assessed by a questionnaire answered by men and women aged 20-62 years (n = 15,986; response rate 75.9%). Logistic regression analysis was used to quantify the relationships between the use of antacids and health-related variables, lifestyle, and sociodemographic characteristics. Approximately 10% of the population had used antacids during the preceding 14 days. There was no overall gender difference. Among those who had no dyspeptic symptoms, 1.5% reported use of antacids, whereas among those who had all three dyspeptic symptoms (heartburn, epigastric pain, peptic ulcer), 46.5% had used antacids. Heartburn was the most important predictor for antacid use in both men (odds ratio [OR] = 8.57 [6.65-11.04]) and women (OR = 9.35 [7.16-12.221) followed by self-reported epigastric pain and peptic ulcer (both: OR = approximately 2). The importance of these self-reported health conditions remained unchanged after adjusting for lifestyle and sociodemographic variables. There were fewer antacid users among unmarried women than married women, and coffee-drinking was inversely associated with antacid use. These findings were consistent in both bivariate and multivariate analysis. The present study provides population-based information showing that self-medication with antacids in Norway appeared to be appropriate. Because dyspeptic symptoms play a major role in the consumption of antacids, this study shows the importance of including information about specific clinical variables in the analysis and interpretation of patterns of drug use.

  18. Prevalence of cold-related complaints, symptoms and injuries in the general population: the FINRISK 2002 cold substudy

    NASA Astrophysics Data System (ADS)

    Raatikka, Veli-Pekka; Rytkönen, Mika; Näyhä, Simo; Hassi, Juhani

    2007-05-01

    The prevalence of cold-related complaints and symptoms in the general population has remained unknown. As part of the nationwide FINRISK 2002 health survey performed in Finland, 8,723 people aged 25 64 years filled in a questionnaire asking about the number of hours spent weekly in cold air, their sensations during cold exposure, cold-related complaints, symptoms of diseases, and degradation of performance. Cold thermal sensations at +5°C to -5°C were reported by 35% of men and 46% of women. Almost all subjects reported at least some cold-related complaints, most commonly musculoskeletal pain (men 30%, women 27%), followed by respiratory (25% / 29%), white finger (15% / 18%) and episodic peripheral circulation symptoms (12% / 15%). Decreased mental or physical performance in cold was reported by 75% of men and 70% of women, most commonly impairing manual dexterity and tactile sense. With declining temperature, the first symptom to emerge was pain in the elbow or the forearm (at -3°C), followed by increased excretion of mucus from the lungs (-5°C), while most other symptoms appeared only at lower temperatures of -15°C to -20°C. Most symptoms showed little or no association with the weekly duration of exposure, with the exception of cold-induced pain at most sites. Although, in general, Finns are well adapted to the cold climate, the high prevalence of cold-related complaints poses a challenge to the health care system in terms of decreased performance and the possibility that such symptoms predict more serious health effects, such as increased mortality.

  19. Forces in General Relativity

    ERIC Educational Resources Information Center

    Ridgely, Charles T.

    2010-01-01

    Many textbooks dealing with general relativity do not demonstrate the derivation of forces in enough detail. The analyses presented herein demonstrate straightforward methods for computing forces by way of general relativity. Covariant divergence of the stress-energy-momentum tensor is used to derive a general expression of the force experienced…

  20. A Unique Patient Population? Health-Related Quality of Life in Adolescent Athletes Versus General, Healthy Adolescent Individuals

    PubMed Central

    Lam, Kenneth C.; Valier, Alison R. Snyder; Bay, R. Curtis; McLeod, Tamara C. Valovich

    2013-01-01

    Context: Normative scores for patient-rated outcome (PRO) instruments are important for providing patient-centered, whole-person care and making informed clinical decisions. Although normative values for the Pediatric Quality of Life Generic Core Scale (PedsQL) have been established in the general, healthy adolescent population, whether adolescent athletes demonstrate similar values is unclear. Objective: To compare PedsQL scores between adolescent athletes and general, healthy adolescent individuals. Design: Cross-sectional study. Setting: Secondary schools. Patients or Other Participants: A convenience sample of 2659 interscholastic athletes (males = 2059, females = 600, age = 15.7 ± 1.1 years) represented the athlete group (ATH), and a previously published normative dataset represented the general, healthy adolescent group (GEN). Intervention(s): All participants completed the PedsQL during 1 testing session. Main Outcome Measure(s): The PedsQL consists of 2 summary scores (total, psychosocial) and 4 subscale scores (physical, emotional, social, school), with higher scores indicating better health-related quality of life (HRQOL). Groups were stratified by age (14, 15, or 16 years old). Independent-samples t tests were conducted to compare between-groups and sex differences. Results: The ATH group scored higher than the GEN group across all ages for total and psychosocial summary scores and for emotional and social functioning subscale scores (P ≤ .005). For physical functioning, scores of the 15-year-old ATH were higher than for their GEN counterparts (P = .001). Both 14- and 15-year-old ATH scored higher than their GEN counterparts for the school functioning subscale (P ≤ .013), but differences between 16-year olds were not significant (P = .228). Male adolescent athletes reported higher scores than female adolescent athletes across all scores (P ≤ .001) except for social functioning (P = .229). Conclusions: Adolescent athletes reported better HRQOL than

  1. How Providing Mentoring Relates to Career Success and Organizational Commitment: A Study in the General Managerial Population

    ERIC Educational Resources Information Center

    Bozionelos, Nikos; Bozionelos, Giorgos; Kostopoulos, Konstantinos; Polychroniou, Panagiotis

    2011-01-01

    Purpose: This study aims to investigate the relationship of mentoring provided with career success and organizational commitment in the general managerial population. Design/methodology/approach: Participants were 194 native British who were employed in a variety of jobs, professions and industries in the United Kingdom. Findings: Mentoring…

  2. Experiences of possession and paranormal phenomena among women in the general population: are they related to traumatic stress and dissociation?

    PubMed

    Sar, Vedat; Alioğlu, Firdevs; Akyüz, Gamze

    2014-01-01

    This study sought to determine the prevalence of experiences of possession and paranormal phenomena (PNP) in the general population and their possible relations to each other and to traumatic stress and dissociation. The study was conducted on a representative female sample recruited from a town in central eastern Turkey. The Dissociative Disorders Interview Schedule, the posttraumatic stress disorder (PTSD) and borderline personality disorder sections of the Structured Clinical Interviews for DSM-IV Axis-I and Personality Disorders, and the Childhood Abuse and Neglect Questionnaire were administered to 628 women. Of these, 127 (20.2%) women reported at least 1 type of PNP and 13 (2.1%) women reported possession. Women with a dissociative disorder reported all types of possession and PNP (except telepathy) more frequently than those without. Whereas women with a trauma history in childhood and adulthood or PTSD reported possession more frequently than those without, PNP were associated with childhood trauma only. Factor analysis yielded 4 dimensions: possession by and/or contact with nonhuman entities, extrasensory communications, possession by a human entity, and precognition. These factors correlated with number of secondary features of dissociative identity disorder and Schneiderian symptoms. Latent class analysis identified 3 groups. The most traumatized group, with predominantly dissociative and trauma-related disorders, had the highest scores on all factors. Notwithstanding their presence in healthy individuals, possession and PNP were associated with trauma and dissociation in a subgroup of affected participants. Both types of experience seem to be normal human capacities of experiencing that may be involved in response to traumatic stress. Given the small numbers, this study should be considered preliminary. PMID:24228817

  3. Experiences of possession and paranormal phenomena among women in the general population: are they related to traumatic stress and dissociation?

    PubMed

    Sar, Vedat; Alioğlu, Firdevs; Akyüz, Gamze

    2014-01-01

    This study sought to determine the prevalence of experiences of possession and paranormal phenomena (PNP) in the general population and their possible relations to each other and to traumatic stress and dissociation. The study was conducted on a representative female sample recruited from a town in central eastern Turkey. The Dissociative Disorders Interview Schedule, the posttraumatic stress disorder (PTSD) and borderline personality disorder sections of the Structured Clinical Interviews for DSM-IV Axis-I and Personality Disorders, and the Childhood Abuse and Neglect Questionnaire were administered to 628 women. Of these, 127 (20.2%) women reported at least 1 type of PNP and 13 (2.1%) women reported possession. Women with a dissociative disorder reported all types of possession and PNP (except telepathy) more frequently than those without. Whereas women with a trauma history in childhood and adulthood or PTSD reported possession more frequently than those without, PNP were associated with childhood trauma only. Factor analysis yielded 4 dimensions: possession by and/or contact with nonhuman entities, extrasensory communications, possession by a human entity, and precognition. These factors correlated with number of secondary features of dissociative identity disorder and Schneiderian symptoms. Latent class analysis identified 3 groups. The most traumatized group, with predominantly dissociative and trauma-related disorders, had the highest scores on all factors. Notwithstanding their presence in healthy individuals, possession and PNP were associated with trauma and dissociation in a subgroup of affected participants. Both types of experience seem to be normal human capacities of experiencing that may be involved in response to traumatic stress. Given the small numbers, this study should be considered preliminary.

  4. General relativity and cosmology

    NASA Astrophysics Data System (ADS)

    Bucher, Martin; Ni, Wei-Tou

    2015-10-01

    This year marks the 100th anniversary of Einstein’s 1915 landmark paper “Die Feldgleichungen der Gravitation” in which the field equations of general relativity were correctly formulated for the first time, thus rendering general relativity a complete theory. Over the subsequent hundred years, physicists and astronomers have struggled with uncovering the consequences and applications of these equations. This paper, which was written as an introduction to six chapters dealing with the connection between general relativity and cosmology that will appear in the two-volume book One Hundred Years of General Relativity: From Genesis and Empirical Foundations to Gravitational Waves, Cosmology and Quantum Gravity, endeavors to provide a historical overview of the connection between general relativity and cosmology, two areas whose development has been closely intertwined.

  5. General Relativity and Energy

    ERIC Educational Resources Information Center

    Jackson, A. T.

    1973-01-01

    Reviews theoretical and experimental fundamentals of Einstein's theory of general relativity. Indicates that recent development of the theory of the continually expanding universe may lead to revision of the space-time continuum of the finite and unbounded universe. (CC)

  6. Statistical issues encountered in the comparison of health-related quality of life in diseased patients to published general population norms: problems and solutions.

    PubMed

    Rose, M S; Koshman, M L; Spreng, S; Sheldon, R

    1999-05-01

    The objectives of this study were (1) to illustrate the statistical problems encountered when comparing health-related quality of life (HRQL) measured by the Medical Outcome Study Short Form-36 (SF-36) in a diseased group to general population norms, and (2) to define age- and gender-standardized dichotomous indicator variables for each health concept and show that these indicator variables facilitate comparisons between the diseased sample and the general population. Our "diseased" group consisted of 136 sequentially consenting patients referred to the syncope clinic for assessment and treatment. Participants completed the SF-36 questionnaire before undergoing diagnostic testing. General population norms for the SF-36 are available from the responses of 2474 participants in the National Survey of Functional Health Status, conducted in 1990 in the United States. Comparison of the SF-36 in a diseased sample with general population norms is difficult, owing to skewed and unusual distributions in both groups. In addition, making comparisons within age and gender strata is difficult if the within strata sample size is small. We propose a dichotomous indicator variable for each health concept that classifies an individual as having impaired health if he or she scored lower than the 25th percentile for the appropriate age and gender general population strata. By definition, the prevalence of impaired health in the general population is 25% for all eight health concepts. Comparison between the eight health-concept variables is easy because the population norm is the same for each of them. These indicator variables are age and gender adjusted, so that even if the sample did not have the age and gender distribution as the general population, comparisons can still be made with the value of 25.

  7. Matter in general relativity

    NASA Technical Reports Server (NTRS)

    Ray, J. R.

    1982-01-01

    Two theories of matter in general relativity, the fluid theory and the kinetic theory, were studied. Results include: (1) a discussion of various methods of completing the fluid equations; (2) a method of constructing charged general relativistic solutions in kinetic theory; and (3) a proof and discussion of the incompatibility of perfect fluid solutions in anisotropic cosmologies. Interpretations of NASA gravitational experiments using the above mentioned results were started. Two papers were prepared for publications based on this work.

  8. Association of Serum Ferritin and Kidney Function with Age-Related Macular Degeneration in the General Population

    PubMed Central

    Oh, Il Hwan; Choi, Eun Young; Park, Joon-Sung; Lee, Chang Hwa

    2016-01-01

    Ferritin is considered to be a marker of the body’s iron stores and has a potential relationship with the systemic manifestations of inflammatory reactions. Data on the association between increased levels of serum ferritin and ocular problems are limited, particularly in relation to age-related macular degeneration (AMD). Serum ferritin levels, as a possible clinical parameter for predicting AMD, were analyzed in anthropometric, biochemical, and ophthalmologic data from a nation-wide, population-based, case-control study (KNHNES IV and V). All native Koreans aged ≥ 20 years and who had no medical illness were eligible to participate. Among them, 2.9% had AMD, and its prevalence was found to increase in the higher ferritin quintile groups (Ptrend < 0.0001). In multiple linear regression analysis, serum ferritin level was closely related to conventional risk factors for AMD. Comparison of early AMD with a control group showed that serum ferritin levels were closely associated with AMD (OR = 1.004, 95% CI = 1.002–1.006), and further adjustment for age, gender, serum iron, and kidney function did not reduce this association (OR = 1.003, 95% CI = 1.001–1.006). Furthermore, the relationship between ferritin quintile and early AMD was dose-dependent. Thus, an increased level of serum ferritin in a healthy person may be a useful indicator of neurodegenerative change in the macula. A large population-based prospective clinical study is needed to confirm these findings. PMID:27096155

  9. Association of Serum Ferritin and Kidney Function with Age-Related Macular Degeneration in the General Population.

    PubMed

    Oh, Il Hwan; Choi, Eun Young; Park, Joon-Sung; Lee, Chang Hwa

    2016-01-01

    Ferritin is considered to be a marker of the body's iron stores and has a potential relationship with the systemic manifestations of inflammatory reactions. Data on the association between increased levels of serum ferritin and ocular problems are limited, particularly in relation to age-related macular degeneration (AMD). Serum ferritin levels, as a possible clinical parameter for predicting AMD, were analyzed in anthropometric, biochemical, and ophthalmologic data from a nation-wide, population-based, case-control study (KNHNES IV and V). All native Koreans aged ≥ 20 years and who had no medical illness were eligible to participate. Among them, 2.9% had AMD, and its prevalence was found to increase in the higher ferritin quintile groups (Ptrend < 0.0001). In multiple linear regression analysis, serum ferritin level was closely related to conventional risk factors for AMD. Comparison of early AMD with a control group showed that serum ferritin levels were closely associated with AMD (OR = 1.004, 95% CI = 1.002-1.006), and further adjustment for age, gender, serum iron, and kidney function did not reduce this association (OR = 1.003, 95% CI = 1.001-1.006). Furthermore, the relationship between ferritin quintile and early AMD was dose-dependent. Thus, an increased level of serum ferritin in a healthy person may be a useful indicator of neurodegenerative change in the macula. A large population-based prospective clinical study is needed to confirm these findings. PMID:27096155

  10. General Relativity Today

    NASA Astrophysics Data System (ADS)

    Blandford, Roger D.

    2016-01-01

    A hundred years after its birth, general relativity has become a highly successful theory in the sese that it has passed many experimental and observational tests and finds widespread application to diverse set of cosmic phenomena. It remains an accurate research field as more tests are deployed, epitomized by the exciting prospect of detecting gravitational radiation directly. General realtivity is the essential foundation of modern cosmology and underlies our detailed description of the black holes and neutron stars that are ultimately responsible for the most powerful and dramatic cosmic sources. The interface with physics on both the largest and the smallest scales continues to be very fertile. In this talk I will attempt to highlight some key steps along the way to general relativity today.

  11. Long-Term Health-Related Quality of Life in German Patients with Juvenile Idiopathic Arthritis in Comparison to German General Population

    PubMed Central

    Barth, Swaantje; Haas, Johannes-Peter; Schlichtiger, Jenny; Molz, Johannes; Bisdorff, Betty; Michels, Hartmut; Hügle, Boris; Radon, Katja

    2016-01-01

    Objective Aims of the study were to investigate health-related quality of life (HRQOL) in adult patients with former diagnosis of Juvenile Idiopathic Arthritis (JIA), to compare their HRQOL with the general population and to identify factors related to a poor outcome. Methods In 2012, a cross-sectional survey was performed by mailing a questionnaire to a large cohort of former and current patients of the German Centre for Rheumatology in Children and Adolescents. Only adult patients (≥18 years) with a diagnosis compatible with JIA were included (n = 2592; response 66%). The questionnaire included information about HRQOL (EQ5D), disease-related questions and socio-demographics. Prevalence and 95% confidence intervals (CI) of problems with mobility, self-care, usual activities, pain and anxiety/depression were standardized to the German general population. Factors associated with low HRQOL in JIA patients were identified using logistic regression models. Results Sixty-two percent of the study population was female; age range was 18–73 years. In all dimensions, JIA patients reported statistically significantly more problems than the general population with largest differences in the pain dimension (JIA patients 56%; 95%CI 55–58%; general population 28%; 26–29%) and the anxiety/depression dimension (28%; 27–29% vs. 4%; 4–5%). Lower HRQOL in JIA patients was associated with female sex, older age, lower level of education, still being under rheumatic treatment and disability. Conclusions HRQOL in adult JIA patients is considerably lower than in the general population. As this cohort includes historic patients the new therapeutic schemes available today are expected to improve HRQOL in future. PMID:27115139

  12. Left ventricular diastolic function in relation to the urinary proteome: A proof-of-concept study in a general population

    PubMed Central

    Zhang, Zhenyu; Staessen, Jan A.; Thijs, Lutgarde; Gu, Yumei; Liu, Yanping; Jacobs, Lotte; Koeck, Thomas; Zürbig, Petra; Mischak, Harald; Kuznetsova, Tatiana

    2014-01-01

    Background In previous studies, we identified two urinary proteomic classifiers, termed HF1 and HF2, which discriminated subclinical diastolic left ventricular (LV) dysfunction from normal. HF1 and HF2 combine information from 85 and 671 urinary peptides, mainly up- or down-regulated collagen fragments. We sought to validate these classifiers in a population study. Methods In 745 people randomly recruited from a Flemish population (49.8 years; 51.3% women), we measured early and late diastolic peak velocities of mitral inflow (E and A) and mitral annular velocities (e' and a') by conventional and tissue Doppler echocardiography, and the urinary proteome by capillary electrophoresis coupled with mass spectrometry. Results In the analyses adjusted for sex, age, body mass index, blood pressure, heart rate, LV mass index and intake of medications, we expressed effect sizes per 1-SD increment in the classifiers. HF1 was associated with 0.204 cm/s lower e' peak velocity (95% confidence interval, 0.057–0.351; p = 0.007) and 0.145 higher E/e' ratio (0.023–0.268; p = 0.020), while HF2 was associated with a 0.174 higher E/e' ratio (0.046–0.302; p = 0.008). According to published definitions, 67 (9.0%) participants had impaired LV relaxation and 96 (12.9%) had elevated LV filling pressure. The odds of impaired relaxation associated with HF1 was 1.38 (1.01–1.88; p = 0.043) and that of increased LV filling pressure associated with HF2 was 1.38 (1.00–1.90; p = 0.052). Conclusions In a general population, the urinary proteome correlated with diastolic LV dysfunction, proving its utility for early diagnosis of this condition. PMID:25065337

  13. Tests of General Relativity

    SciTech Connect

    Kramer, Michael

    2011-09-22

    The last years have seen continuing activities in the exploration of our understanding of gravity, motivated by results from precision cosmology and new precision astrophysical experiments. At the centre of attention lies the question as to whether general relativity is the correct theory of gravity. In answering this question, we work not only towards correctly interpreting the phenomenon of 'dark energy' but also towards the goal of achieving a quantum theory of gravity. In these efforts, the observations of pulsars, especially those in binary systems, play an important role. Pulsars do not only provide the only evidence for the existence of gravitational waves so far, but they also provide precision tests of general relativity and alternative theories of gravity. This talk summarizes the current state-of-art in these experiments and looks into the future.

  14. Lead exposure in the general population of the Metropolitan Area of Barcelona: blood levels and related factors.

    PubMed

    Solé, E; Ballabriga, A; Dominguez, C

    1998-12-11

    A cross-sectional study was conducted on 254 individuals not occupationally exposed to lead to determine the degree of lead exposure in the general population of the Metropolitan Area of Barcelona. Blood lead levels (BPb) were analysed by atomic absorption spectrophotometry and zinc protoporphyrin (ZPP) by haemofluorimetry. Blood lead levels were analysed with respect to individuals' age, sex, area of residence, the season of the year the blood was drawn and ZPP. Mean blood lead in our series was 0.22 +/- 0.011 mumol/l (mean +/- S.E.); no significant differences were found with respect to area of residence, sex or season. A linear relationship was observed between BPb and individuals' age (BPb = 0.08 + 0.05 x age; r = 0.37). The prevalence of lead intoxication (BPb > 0.48 mumol/l) was 7.1%. No linear relationship was observed between BPb and ZPP. ZPP determination does not appear to be a good screening method for lead intoxication since it presents low specificity and sensitivity values with an area below the ROC curve similar to the null value line (area below the curve = 0.5052, IC 95% = 0.443-0.568). We conclude that lead exposure does not constitute a serious health problem in the area studied, since BPb levels found are far below the toxic limit and the prevalence of intoxication is similar to that reported in other studies conducted in other developed countries.

  15. General Relativity and Gravitation

    NASA Astrophysics Data System (ADS)

    Ashtekar, Abhay; Berger, Beverly; Isenberg, James; MacCallum, Malcolm

    2015-07-01

    Part I. Einstein's Triumph: 1. 100 years of general relativity George F. R. Ellis; 2. Was Einstein right? Clifford M. Will; 3. Cosmology David Wands, Misao Sasaki, Eiichiro Komatsu, Roy Maartens and Malcolm A. H. MacCallum; 4. Relativistic astrophysics Peter Schneider, Ramesh Narayan, Jeffrey E. McClintock, Peter Mészáros and Martin J. Rees; Part II. New Window on the Universe: 5. Receiving gravitational waves Beverly K. Berger, Karsten Danzmann, Gabriela Gonzalez, Andrea Lommen, Guido Mueller, Albrecht Rüdiger and William Joseph Weber; 6. Sources of gravitational waves. Theory and observations Alessandra Buonanno and B. S. Sathyaprakash; Part III. Gravity is Geometry, After All: 7. Probing strong field gravity through numerical simulations Frans Pretorius, Matthew W. Choptuik and Luis Lehner; 8. The initial value problem of general relativity and its implications Gregory J. Galloway, Pengzi Miao and Richard Schoen; 9. Global behavior of solutions to Einstein's equations Stefanos Aretakis, James Isenberg, Vincent Moncrief and Igor Rodnianski; Part IV. Beyond Einstein: 10. Quantum fields in curved space-times Stefan Hollands and Robert M. Wald; 11. From general relativity to quantum gravity Abhay Ashtekar, Martin Reuter and Carlo Rovelli; 12. Quantum gravity via unification Henriette Elvang and Gary T. Horowitz.

  16. Correlates of existential well-being and their association with health-related quality of life in breast cancer survivors compared with the general population.

    PubMed

    Shin, Hae Won; Noh, Dong Young; Lee, Eun Sook; Nam, Seok Jin; Park, Byeong Woo; Ahn, Sei Hyun; Yun, Young Ho

    2009-11-01

    The aim was to evaluate the correlates of existential well-being (EWB) and investigate the relationship between EWB and health-related quality of life (HRQOL) according to the McGill Quality of Life Questionnaire (MQOL) in breast cancer survivors (BCS) and in the general population. BCS (N = 1,933) recruited from five large hospitals completed a mailed survey, which included the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (QLQ-C30), Quality of Life Questionnaire Breast Cancer Module (QLQ-BR23) and the MQOL. Reference data were derived from a representative sample of the Korean adult population composed of 500 women selected by a nationwide random route technique. Multiple logistic regression analysis showed that members of the general population with a lower educational status were more likely to report poor EWB. However, among BCS, correlates that were associated with poor EWB included lower monthly income, lower educational status, unemployment and comorbidities. Almost all factors listed on the HRQOL questionnaire were correlated with EWB in BCS as well as in the general population (P < 0.001). Factors listed on the QLQ-C30 that were correlated to a clinically meaningful extent with EWB in the general population included physical functioning, nausea and vomiting, and appetite loss, whereas among BCS, insomnia and distress over hair loss were meaningfully correlated with EWB. Compared with general population, BCS showed different EWB correlates and distinct associations with HRQOL findings. Our data suggest that socio-economic status and comorbidities influence on their EWB.

  17. Tachyons in general relativity

    SciTech Connect

    Schwartz, Charles

    2011-05-15

    We consider the motion of tachyons (faster-than-light particles) in the framework of general relativity. An important feature is the large contribution of low energy tachyons to the energy-momentum tensor. We also calculate the gravitational field produced by tachyons in particular geometric arrangements; and it appears that there could be self-cohering bundles of such matter. This leads us to suggest that such theoretical ideas might be relevant to major problems (dark matter and dark energy) in current cosmological models.

  18. Health-related quality of life in chronic myeloid leukemia patients receiving long-term therapy with imatinib compared with the general population.

    PubMed

    Efficace, Fabio; Baccarani, Michele; Breccia, Massimo; Alimena, Giuliana; Rosti, Gianantonio; Cottone, Francesco; Deliliers, Giorgio Lambertenghi; Baratè, Claudia; Rossi, Antonella Russo; Fioritoni, Giuseppe; Luciano, Luigia; Turri, Diamante; Martino, Bruno; Di Raimondo, Francesco; Dabusti, Melissa; Bergamaschi, Micaela; Leoni, Pietro; Simula, Maria Pina; Levato, Luciano; Ulisciani, Stefano; Veneri, Dino; Sica, Simona; Rambaldi, Alessandro; Vignetti, Marco; Mandelli, Franco

    2011-10-27

    The main objective of this study was to investigate whether patients with chronic myeloid leukemia (CML) in treatment with long-term therapy imatinib have a different health-related quality-of-life (HRQOL) profile compared with the general population. In total, 448 CML patients were enrolled, and the SF-36 Health Survey was used to compare generic HRQOL profiles. Symptoms were also assessed. HRQOL comparisons were adjusted for key possible confounders. The median age of patients was 57 years and the median time of imatinib treatment was 5 years (range 3-9 years). The largest HRQOL differences were found in younger patients. In particular, patients aged between 18 and 39 years had marked impairments in role limitations because of physical and emotional problems, respectively: -22.6 (P < .001), -22.3 (P < .001). Patients with CML age 60 or older had a HRQOL profile very similar to that reported by the general population. Women had a worse profile than men when each were compared with their peers in the general population. Fatigue was the most frequently reported symptom. The HRQOL of CML patients is comparable with that of population norms in many areas, however, younger and female patients seem to report the major limitations.

  19. HIV-related risk behaviors among the general population: a survey using Audio Computer-Assisted Self-Interview in 3 cities in Vietnam.

    PubMed

    Vu, Lan T H; Nadol, Patrick; Le, Linh Cu

    2015-03-01

    This study used a confidential survey method-namely, Audio Computer-Assisted Self-Interview (ACASI)-to gather data about HIV-related risk knowledge/behaviors among the general population in Vietnam. The study sample included 1371 people aged 15 to 49 years in 3 cities-Hanoi, Da nang, and Can Tho. Results indicated that 7% of participants had ever had nonconsensual sex, and 3.6% of them had ever had a one-night stand. The percentage of male participants reported to ever have sex with sex workers was 9.6% and to ever inject drugs was 4.3%. The proportion of respondents who had ever tested for HIV was 17.6%. The risk factors and attitudes reported in the survey indicate the importance of analyzing risk behaviors related to HIV infection among the general population. Young people, especially men in more urbanized settings, are engaging in risky behaviors and may act as a "bridge" for the transmission of HIV from high-risk groups to the general population in Vietnam.

  20. Reappraisal of the relation between blood lead concentration and blood pressure among the general population in Taiwan

    PubMed Central

    Chu, N. F.; Liou, S. H.; Wu, T. N.; Chang, P. Y.

    1999-01-01

    OBJECTIVES: The relation between blood lead concentration (PbB) and blood pressure was examined in a Taiwan nationwide population survey of PbB from July 1993 to June 1994. METHODS: After multistage sampling procedures, 2800 subjects (1471 males and 1329 females) with a mean (range) age of 44 (15-85) years were enrolled in this study. Anthropometric, blood pressure, and lifestyle factors were measured during household visits. The PbB was measured with a flameless atomic absorption spectrophotometer and all specimens were analysed in triplicate. RESULTS: The mean (range) PbB among all study subjects was 6.5 (0.1-69.1) micrograms/dl; among males it was 7.3 (0.1-69.1) micrograms/dl and among females 5.7 (0.1-40.1) micrograms/dl). The mean (range) systolic blood pressure among all subjects was 123 (80-210) mm Hg, among males it was 127 (80-200) mm Hg and among females 119 (80- 210) mm Hg. The diastolic blood pressure among all subjects was 78 (40- 150) mm Hg; among males it was 80 (40-130) mm Hg; and among females 75 (40-150) mm Hg. Age, body height, body weight, and body mass index (BMI) were significantly correlated with systolic blood pressure or diastolic blood pressure in both sexes. The PbB (or the natural logarithmic transformed PbB) was not significantly correlated with blood pressure among males or females. After adjustment for the potential confounders of age, age2, BMI, milk intake, alcohol consumption, and cigarette smoking, systolic blood pressure was significantly associated with PbB among males with a regression coefficient (beta) of 0.185 (p = 0.015). No significant association between PbB and blood pressure was found among females. CONCLUSIONS: From this study, only a weak association between systolic blood pressure and PbB was found among males. There was no strong evidence that PbB was a good predictor of blood pressure. However, the possibility that long term high body lead burden could cause high blood pressure could not be ruled out on the basis

  1. Generalized uncertainty relations

    NASA Astrophysics Data System (ADS)

    Akten, Burcu Elif

    1999-12-01

    The Heisenberg uncertainty relation has been put into a stronger form by Schrödinger and Robertson. This inequality is also canonically invariant. We ask if there are other independent inequalities for higher orders. The aim is to find a systematic way for writing these inequalities. After an overview of the Heisenberg and Schrödinger-Robertson inequalities and their minimal states in Chapter 1, we start by constructing the higher order invariants in Chapter 2. We construct some of the simpler invariants by direct calculation, which suggests a schematic way of representing all invariants. Diagrams describing invariants help us see their structure and their symmetries immediately and various simplifications in their calculations are obtained as a result. With these new tools, a more systematic approach to construct and classify invariants using group theory is introduced next. In Chapter 4, various methods of obtaining higher order inequalities are discussed and compared. First, the original approach of HUR is applied to the next order and a new inequality is obtained by working in a specific frame where the expectation value tensor is in its simplest form. However, this method can not be used for higher orders as the significant simplifications of a specific frame is no longer available. The second method consists of working with a state vector written as a sum of the eigenvectors of the operator (qp)s and has a Gaussian distribution about the state which makes s=0 . Finally, we try to obtain a general inequality for a whole class of invariants by writing the state vector as a sum of harmonic oscillator eigenstates. In Chapter 4, realistic measurements of the canonical variables are discussed in relation to the uncertainty relations. Finally, in Chapter 5, squeezed state generation by an optical parametric oscillator is described as an explicit demonstration of the HUR for the electromagnetic field. A similar approach is developed for testing higher order

  2. Directions in General Relativity

    NASA Astrophysics Data System (ADS)

    Hu, B. L.; Ryan, M. P., Jr.; Vishveshwara, C. V.

    2005-10-01

    Preface; Dieter Brill: a spacetime perspective; 1. Thawing the frozen formalism: the difference between observables and what we observe A. Anderson; 2. Jacobi's action and the density of states J. D. Brown and J. W. York; 3. Decoherence of correlation histories E. Calzetta and B. L. Hu; 4. The initial value problem in light of Ashtekar's variables R. Capovilla, J. Dell and T. Jacobson; 5. Status report on an axiomatic basis for functional integration P. Cartier and C. DeWitt-Morette; 6. Solution of the coupled Einstein constraints on asymptotically Euclidean manifolds Y. Choquet-Bruhat; 7. Compact Cauchy horizons and Cauchy surfaces P. Chrusciel and J. Isenberg; 8. The classical electron J. M. Cohen and E. Mustafa; 9. Gauge (in)variance, mass and parity in D=3 revisited S. Deser; 10. Triality, exceptional Lie groups and Dirac operators F. Flaherty; 11. The reduction of the state vector and limitations on measurement in the quantum mechanics of closed systems J. B. Hartle; 12 Quantum linearization instabilities of de Sitter spacetime A. Higuchi; 13. What is the true description of charged black holes? G. T. Horowitz; 14. Limits on the adiabatic index in static stellar models L. Lindblom and A. K. M. Masood-ul-Alam; 15. On the relativity of rotation B. Mashhoon; 16. Recent progress and open problems in linearization stability V. E. Moncrief; 17. Brill waves N. Ó Murchadha; 18. You can't get there from here: constraints on topology change K. Schleich and D. M. Witt; 19. Time, measurement and information loss in quantum cosmology L. Smolin; 20. Impossible measurements on quantum fields R. Sorkin; 21. A new condition implying the existence of a constant mean curvature foliation F. J. Tipler; 22. Maximal slices in stationary spacetimes with ergoregions R. M. Wald; 23. (1 + 1) - Dimensional methods for general relativity J. H. Yoon; 24. Coalescence of primal gravity waves to make cosmological mass without matter D. E. Holz, W. A. Miller, M. Wakano and J. A. Wheeler.

  3. Influence of membrane sodium transport upon the relation between blood lead and blood pressure in a general male population.

    PubMed Central

    Moreau, T; Hannaert, P; Orssaud, G; Huel, G; Garay, R P; Claude, J R; Juguet, B; Festy, B; Lellouch, J

    1988-01-01

    Five red blood cell cation transport systems (RBCTS), together with blood lead level and blood pressure, were measured in 129 male adult subjects who were not occupationally exposed to lead or subsequent to a course of treatment for hypertension. Blood lead was positively related with systolic blood pressure, and to a lesser degree with diastolic blood pressure. Blood lead was found significantly negatively related to one of the RBCTS, Na+,K+ cotransport, and in addition, Na+,K+ cotransport appeared negatively related to blood pressure. Final results showed that blood lead no longer accounts for an increase in systolic blood pressure when Na+,K+ cotransport was taken into account; the same trend was observed with diastolic blood pressure. These findings suggest that a blood lead-related Na+,K+ cotransport impairment could explain the blood pressure increase observed to parallel the blood lead increase. PMID:3203645

  4. The Patient-Centered Medical Home: How Is It Related to Quality and Equity Among the General Adult Population?

    PubMed

    Reibling, Nadine

    2016-10-01

    This study investigates whether patient-reported characteristics of the medical home are associated with improved quality and equity of preventive care, advice on health habits, and emergency department use. We used adjusted risk ratios to examine the association between medical home characteristics and care measures based on the 2010 Medical Expenditure Panel Survey. Medical home characteristics are associated with 6 of the 11 outcome measures, including flu shots, smoking advice, exercise advice, nutrition advice, all advice, and emergency department visits. Educational and income groups benefit relatively equally from medical home characteristics. However, compared with insurance and access to a provider, medical home characteristics have little influence on overall disparities in care. In sum, our findings support that medical home characteristics can improve quality and reduce emergency visits but we find no evidence that medical home characteristics alleviate disparities in care.

  5. Smoking and Health-Related Quality of Life in the General Population. Independent Relationships and Large Differences According to Patterns and Quantity of Smoking and to Gender

    PubMed Central

    Coste, Joël; Quinquis, Laurent; D'Almeida, Samuel; Audureau, Etienne

    2014-01-01

    Background Relationships between smoking and health-related quality of life (HRQoL) in the general population remain unclear. Objectives To quantify the independent associations between smoking patterns and HRQoL and to identify any threshold or non-linear tendencies in these associations. Methods A national representative, cross-sectional household survey of the French general non institutionalized population included 7525 men and 8486 women, aged 25–64 year in 2003. Scores on the eight subscales of the Medical Outcomes Study 36-item Short Form were the primary outcomes. Linear regression analyses were used to evaluate the associations between HRQoL and smoking history, quantity of smoking and smoking cessation while controlling for various socio-economic variables, depression, alcohol dependence and pathological conditions. Analyses were conducted in 2013. Results Independent associations between smoking and HRQoL were found, including small positive associations for occasional or light smoking (up to 5 cigarettes per day), and larger and diffuse negative associations above this threshold. Much weaker associations and higher thresholds for negative HRQoL were found for women than for men. For ex-smokers of both genders, HRQoL was found to be better between 2 and 5 years after quitting. Conclusions Smoking was independently related to HRQoL, with large differences according to the pattern and quantity of smoking, and to gender. These results may have considerable relevance both for public health action and care of smokers. PMID:24637739

  6. Migraine and tension-type headache in a general population: precipitating factors, female hormones, sleep pattern and relation to lifestyle.

    PubMed

    Rasmussen, B K

    1993-04-01

    In a cross-sectional epidemiological study of headache disorders information on precipitating factors, age at onset, influence of menstruation and pregnancy and use of oral contraceptives was collected. The presence of migraine and tension-type headache was ascertained by a clinical interview and examination using the operational diagnostic criteria of the International Headache Society. The prevalence of migraine and tension-type headache was also analysed in relation to variables of lifestyle: physical activity, smoking, consumption of coffee, alcohol intake and sleep pattern. In both migraine and tension-type headache, the most conspicuous precipitating factor was stress and mental tension. Other common precipitants were alcohol, weather changes and menstruation. Disappearance or substantial improvement of the headache during pregnancy was more frequent in migraineurs than in tension-type headache sufferers. The age at onset of both migraine and tension-type headache differs between men and women. Female hormones may be an important factor responsible for the sex difference of headache disorders. The level of physical activity showed no association with migraine, but a significantly higher prevalence of tension-type headache in men with exclusively sedentary activity emerged. Smoking, coffee and alcohol consumption showed no significant associations with the headache disorders. Sleep pattern was significantly associated with migraine and tension-type headache in both univariate and multivariate analyses. In conclusion, migraine and tension-type headache seem to be different with regard to a number of endogenous and exogenous factors.

  7. Seeds of General Relativity.

    ERIC Educational Resources Information Center

    Stauffer, Frederic R.

    1984-01-01

    Proposes novel methods of solving mechanics and dynamics problems by changing frames of reference. Uses these ideas to pursue Einstein's notions of inertial and uniformly rotating reference frames, gravitational and inertial mass, and the gravitational bending of light in relation to the simple original problem. (JM)

  8. Health related quality of life in trauma patients. Data from a one-year follow up study compared with the general population

    PubMed Central

    2011-01-01

    Background Trauma patients have impaired health-related quality of life (HRQOL) after trauma. The aim of the study was to assess HRQOL during the first year after trauma and hospital stay in trauma patients admitted to an intensive-care unit (ICU) for >24 hours compared with non-ICU trauma patients and the general population, and to identify predictors of HRQOL. Methods A prospective one-year follow-up study of 242 trauma patients received by the trauma team of a trauma referral centre in Norway was performed. HRQOL was measured using the Medical Outcomes Study Short Form 36 (SF-36) at 3 and 12 months. Results The mean age of the cohort was 42.3 years (95% CI, 40.4-44.3 years). The median Injury Severity Score (ISS) was 10, interquartile range 16. The HRQOL improved significantly from the 3 to the 12 months follow up in the trauma patients. However their scores were significantly lower for most subscales of SF-36 compared to the general population. Significant differences between ICU and non-ICU patients at 12 months were observed only for physical functioning and role physical subscales. Optimism was an independent predictor of good HRQOL at 12 months, in all dimensions (beta, 0.95-2.45). A higher depression score at baseline predicted lower HRQOL in four of eight dimensions (beta -1.1 to -1.70). In addition, better physical functioning was predicted by lower age (beta, -0.20), and having head injury (reference) as the most severe injury vs. spine or extremity injuries (beta, -9.49 and -10.85), and better mental health by higher age (beta, 0.21) and being employed or studying before the trauma (beta, 12.27). In addition to optimism good general health was predicted by lower score for post-traumatic stress (PTS) symptoms at baseline (beta, -0.27) and lower ISS score (beta -10.59). Conclusions The HRQOL improved significantly from the 3 to the 12 months follow up in our sample. However their scores were significantly lower for most subscales of SF-36 compared to the

  9. Depression, anxiety and their comorbidity in the Swedish general population: point prevalence and the effect on health-related quality of life

    PubMed Central

    Carlbring, Per; Heedman, Åsa; Paxling, Björn; Andersson, Gerhard

    2013-01-01

    Background. Depression and anxiety disorders are major world-wide problems. There are no or few epidemiological studies investigating the prevalence of depression, generalized anxiety disorder and anxiety disorders in general in the Swedish population. Methods. Data were obtained by means of a postal survey administered to 3001 randomly selected adults. After two reminders response rate was 44.3%. Measures of depression and general anxiety were the 9-item Patient Health Questionnaire Depression Scale (PHQ-9) and the 7-item Generalized Anxiety Disorder Scale (GAD-7). The PHQ-9 identified participants who had experienced clinically significant depression (PHQ-9 ≥ 10), and who had a diagnosis of major depression (defined by using a PHQ-9 scoring algorithm). Clinically significant anxiety was defined as having a GAD-7 score ≥ 8. To specifically measure generalized anxiety disorder, the Generalized Anxiety Disorder Questionnaire-IV (GAD-Q-IV) was used with an established cut-off. Health-related quality of life was measured using the EuroQol (EQ-5D). Experiences of treatments for psychiatric disorders were also assessed. Results. Around 17.2% (95% CI: 15.1–19.4) of the participants were experiencing clinically significant depression (10.8%; 95% CI: 9.1–12.5) and clinically significant anxiety (14.7%; 95% CI: 12.7–16.6). Among participants with either clinically significant depression or anxiety, nearly 50% had comorbid disorders. The point prevalence of major depression was 5.2% (95% CI: 4.0–6.5), and 8.8% (95% CI: 7.3–10.4) had GAD. Among those with either of these disorders, 28.2% had comorbid depression and GAD. There were, generally, significant gender differences, with more women having a disorder compared to men. Among those with depression or anxiety, only between half and two thirds had any treatment experience. Comorbidity was associated with higher symptom severity and lower health-related quality of life. Conclusions. Epidemiological data from

  10. Current sources of lead exposure and their relative contributions to the blood lead levels in the general adult population of Northern France: The IMEPOGE Study, 2008-2010.

    PubMed

    Tagne-Fotso, Romuald; Leroyer, Ariane; Howsam, Mike; Dehon, Betty; Richeval, Camille; Nisse, Catherine

    2016-01-01

    There is justification for limiting lead (Pb) exposure as much as possible, given its impact on health at low concentrations. Consequently, the aim of this study was to measure blood lead levels (BLL) and examine exposure factors related to BLL variations in the general adult population of northern France, a current and past industrial area. Two thousand inhabitants of northern France, aged between 20 and 59 years, were recruited using the quota method with caution. Blood lead levels were quantified by inductively coupled plasma-mass spectroscopy (ICP-MS), and variation factors were studied separately in men and women using multivariate stepwise linear and logistic regression models. The geometric mean of the BLL was 18.8 μg/L (95% confidence interval [CI]: 18.3-19.3). Occupational factors affected BLL only in men and represented 14% of total explained variance of BLL. External occupational factors significantly increasing mean levels of BLL were tobacco, consumption of some beverages (wine, coffee, tea, and/or tap water), raw vegetables, housing characteristics (built prior to 1948, Pb piping in the home) and do-it-yourself or leisure activities (paint stripping or rifle shooting). Consumption habits accounted together for 25% and 18% of the total explained variance, respectively, in men and women. Industrial environment did not significantly contribute to BLL variations. Blood lead levels observed in the general population of this industrial part of France did not appear to be excessively elevated compared to values found internationally. Nonetheless, these BLL remain a public health issue in regard to nonthreshold toxicity attributed to Pb. PMID:27074096

  11. Current sources of lead exposure and their relative contributions to the blood lead levels in the general adult population of Northern France: The IMEPOGE Study, 2008-2010.

    PubMed

    Tagne-Fotso, Romuald; Leroyer, Ariane; Howsam, Mike; Dehon, Betty; Richeval, Camille; Nisse, Catherine

    2016-01-01

    There is justification for limiting lead (Pb) exposure as much as possible, given its impact on health at low concentrations. Consequently, the aim of this study was to measure blood lead levels (BLL) and examine exposure factors related to BLL variations in the general adult population of northern France, a current and past industrial area. Two thousand inhabitants of northern France, aged between 20 and 59 years, were recruited using the quota method with caution. Blood lead levels were quantified by inductively coupled plasma-mass spectroscopy (ICP-MS), and variation factors were studied separately in men and women using multivariate stepwise linear and logistic regression models. The geometric mean of the BLL was 18.8 μg/L (95% confidence interval [CI]: 18.3-19.3). Occupational factors affected BLL only in men and represented 14% of total explained variance of BLL. External occupational factors significantly increasing mean levels of BLL were tobacco, consumption of some beverages (wine, coffee, tea, and/or tap water), raw vegetables, housing characteristics (built prior to 1948, Pb piping in the home) and do-it-yourself or leisure activities (paint stripping or rifle shooting). Consumption habits accounted together for 25% and 18% of the total explained variance, respectively, in men and women. Industrial environment did not significantly contribute to BLL variations. Blood lead levels observed in the general population of this industrial part of France did not appear to be excessively elevated compared to values found internationally. Nonetheless, these BLL remain a public health issue in regard to nonthreshold toxicity attributed to Pb.

  12. Relative effects of educational level and occupational social class on body concentrations of persistent organic pollutants in a representative sample of the general population of Catalonia, Spain.

    PubMed

    Gasull, Magda; Pumarega, José; Rovira, Gemma; López, Tomàs; Alguacil, Juan; Porta, Miquel

    2013-10-01

    Scant evidence is available worldwide on the relative influence of occupational social class and educational level on body concentrations of persistent organic pollutants (POPs) in the general population. The objective was to analyse such influence in a representative sample of the general population of Catalonia, Spain. Participants in the Catalan Health Interview Survey aged 18-74 were interviewed face-to-face, gave blood, and underwent a physical exam. The role of age, body mass index (BMI), and parity was analysed with General Linear Models, and adjusted geometric means (GMs) were obtained. Crude (unadjusted) concentrations were higher in women and men with lower education, and in women, but not men, in the less affluent social class. After adjusting for age, in women there were no associations between POP levels and social class or education. After adjusting for age and BMI, men in the less affluent class had higher p,p'-DDE concentrations than men in class I (p-value=0.016), while men in class IV had lower HCB than men in the upper class (p-value<0.03). Also in contrast with some expectations, positive associations between education and POP levels were observed after adjusting for age and BMI in men; e.g., men with university studies had higher HCB concentrations than men with first stage of primary schooling (adjusted GM 153.9 and 80.5ng/g, respectively) (p-value<0.001). When education and social class were co-adjusted for, some positive associations with education in men remained statistically significant, whereas class remained associated only with p,p'-DDE. Educational level influenced blood concentrations of POPs more than occupational social class, especially in men. In women, POP concentrations were mainly explained by age/birth cohort, parity and BMI. In men, while concentrations were also mainly explained by age/birth cohort and BMI, both social class and education showed positive associations. Important characteristics of socioeconomic groups as age

  13. A "Suicide Pill" for Older People: Attitudes of Physicians, the General Population, and Relatives of Patients Who Died after Euthanasia or Physician-Assisted Suicide in the Netherlands

    ERIC Educational Resources Information Center

    Rurup, Mette L.; Onwuteaka-Philipsen, Bregje D.; van der Wal, Gerrit; van der Heide, Agnes; van Der Maas, Paul J.

    2005-01-01

    In the Netherlands there has been ongoing debate in the past 10 years about the availability of a hypothetical "suicide pill", with which older people could end their life in a dignified way if they so wished. Data on attitudes to the suicide pill were collected in the Netherlands from 410 physicians, 1,379 members of the general population, and…

  14. The relative odds of lifetime health conditions and infectious diseases among men who have sex with men compared with a matched general population sample.

    PubMed

    Swartz, James A

    2015-03-01

    To address the understudy of health conditions and infectious diseases that are not strictly related to sexual transmission among men who have sex with men (MSM), this study examined the relative odds of 10 health conditions and two infectious diseases in a sample of MSM compared with a matched general population sample. MSM (N = 653) living mainly in Chicago were sampled through successive administrations of an Internet-based survey (2008-2010) that assessed physical and mental health, substance use, and HIV status. Propensity score matching was used to obtain a demographically comparable sample of men (N = 653) from aggregated administrations (2008-2012) of the National Survey on Drug Use and Health. Multivariate Firth logistic regressions compared the odds of ever having been diagnosed with each condition or disease, controlling for demographics, substance use, psychological distress, and HIV/AIDS status. MSM were more likely (p < .01) to have experienced: ulcers (odds ratio [OR] = 2.3), hypertension (OR = 2.1), liver disease (OR = 5.7), and sexually transmitted infections other than HIV/AIDS (OR = 8.9). Two other conditions, pneumonia and pancreatitis, as well as tuberculosis, were significant at p < .05 but below the statistical threshold used to reduce alpha error. The findings suggest that relative to non-sexual-minority men, MSM are more likely to experience a range of health conditions not specifically attributable to HIV/AIDS, sexual behavior, psychological distress, or substance use. The implications for research on the health status and provision of health care to MSM in light of the study findings are considered.

  15. Cosmological tests of general relativity.

    PubMed

    Hut, P

    1977-05-12

    General relativity theory could be tested on a cosmological scale by measuring the Hubble constant and the deceleration parameter, if, in addition, everything could be known about the matter filling the universe. If, on the other hand, nothing could be presupposed about the matter content of the universe, general relativity could not be tested by measuring any number of time derivatives of the scale factor. But upon making the assumption of a universe filled with a non-interacting mixture of non-relativistic matter and radiation we can in principle test general relativity by measuring the first five derivatives of the scale factor. In the following, some general relations are presented using this assumption.

  16. Knowledge, Attitudes and Practices (KAP) related to the Pandemic (H1N1) 2009 among Chinese General Population: a Telephone Survey

    PubMed Central

    2011-01-01

    Background China is at greatest risk of the Pandemic (H1N1) 2009 due to its huge population and high residential density. The unclear comprehension and negative attitudes towards the emerging infectious disease among general population may lead to unnecessary worry and even panic. The objective of this study was to investigate the Chinese public response to H1N1 pandemic and provide baseline data to develop public education campaigns in response to future outbreaks. Methods A close-ended questionnaire developed by the Chinese Center for Disease Control and Prevention was applied to assess the knowledge, attitudes and practices (KAP) of pandemic (H1N1) 2009 among 10,669 responders recruited from seven urban and two rural areas of China sampled by using the probability proportional to size (PPS) method. Results 30.0% respondents were not clear whether food spread H1N1 virusand. 65.7% reported that the pandemic had no impact on their life. The immunization rates of the seasonal flu and H1N1vaccine were 7.5% and 10.8%, respectively. Farmers and those with lower education level were less likely to know the main transmission route (cough or talk face to face). Female and those with college and above education had higher perception of risk and more compliance with preventive behaviors. Relationships between knowledge and risk perception (OR = 1.69; 95%CI 1.54-1.86), and knowledge and practices (OR = 1.57; 95%CI 1.42-1.73) were found among the study subjects. With regard to the behavior of taking up A/H1N1 vaccination, there are several related factors found in the current study population, including the perception of life disturbed (OR = 1.29; 95%CI 1.11-1.50), the safety of A/H1N1 vaccine (OR = 0.07; 95%CI 0.04-0.11), the knowledge of free vaccination policy (OR = 7.20; 95%CI 5.91-8.78), the state's priority vaccination strategy(OR = 1.33; 95%CI 1.08-1.64), and taking up seasonal influenza vaccine behavior (OR = 4.69; 95%CI 3.53-6.23). Conclusions This A/H1N1 epidemic

  17. Speed limits in general relativity

    NASA Astrophysics Data System (ADS)

    Low, Robert J.

    1999-02-01

    Some standard results on the initial value problem of general relativity in matter are reviewed. These results are applied first to show that in a well defined sense, finite perturbations in the gravitational field travel no faster than light, and second to show that it is impossible to construct a warp drive as considered by Alcubierre (1994 The warp drive: hyper-fast travel within general relativity Class. Quantum Grav. 11 L73-7) in the absence of exotic matter.

  18. [Does population ecology have general laws?].

    PubMed

    Turchin, P V

    2002-01-01

    There is a widespread opinion among ecologists that ecology lacks general laws. In this paper the author argues that this opinion is mistaken. Taking the case of population dynamics, the author points out that there are several very general law-like propositions that provide the theoretical basis for most population dynamics models that were developed to address specific issues. Some of these foundational principles, like the law of exponential growth, are logically very similar to certain law of physics (Newton's law of intertia, for example, is almost a direct analogue of exponential growth). The author discusses two other principles (population self-limitation and resource-consumer oscillations), as well as the more elementary postulates that underlie them. None of the "laws" that the author proposes for population ecology are new. Collectively ecologists have been using these general principles in guiding development of their models and experiments since the days of Lotka, Volterra, and Gause.

  19. Spinning fluids in general relativity

    NASA Technical Reports Server (NTRS)

    Ray, J. R.; Smalley, L. L.

    1982-01-01

    General relativity field equations are employed to examine a continuous medium with internal spin. A variational principle formerly applied in the special relativity case is extended to the general relativity case, using a tetrad to express the spin density and the four-velocity of the fluid. An energy-momentum tensor is subsequently defined for a spinning fluid. The equations of motion of the fluid are suggested to be useful in analytical studies of galaxies, for anisotropic Bianchi universes, and for turbulent eddies.

  20. Quasilocal Hamiltonians in general relativity

    SciTech Connect

    Anderson, Michael T.

    2010-10-15

    We analyze the definition of quasilocal energy in general relativity based on a Hamiltonian analysis of the Einstein-Hilbert action initiated by Brown-York. The role of the constraint equations, in particular, the Hamiltonian constraint on the timelike boundary, neglected in previous studies, is emphasized here. We argue that a consistent definition of quasilocal energy in general relativity requires, at a minimum, a framework based on the (currently unknown) geometric well-posedness of the initial boundary value problem for the Einstein equations.

  1. General Relativity: Geometry Meets Physics

    ERIC Educational Resources Information Center

    Thomsen, Dietrick E.

    1975-01-01

    Observing the relationship of general relativity and the geometry of space-time, the author questions whether the rest of physics has geometrical explanations. As a partial answer he discusses current research on subatomic particles employing geometric transformations, and cites the existence of geometrical definitions of physical quantities such…

  2. Dimensional Analysis and General Relativity

    ERIC Educational Resources Information Center

    Lovatt, Ian

    2009-01-01

    Newton's law of gravitation is a central topic in the first-year physics curriculum. A lecturer can go beyond the physical details and use the history of gravitation to discuss the development of scientific ideas; unfortunately, the most recent chapter in this history, general relativity, is not covered in first-year courses. This paper discusses…

  3. Testing general relativity on accelerators

    NASA Astrophysics Data System (ADS)

    Kalaydzhyan, Tigran

    2015-11-01

    Within the general theory of relativity, the curvature of spacetime is related to the energy and momentum of the present matter and radiation. One of the more specific predictions of general relativity is the deflection of light and particle trajectories in the gravitational field of massive objects. Bending angles for electromagnetic waves and light in particular were measured with a high precision. However, the effect of gravity on relativistic massive particles was never studied experimentally. Here we propose and analyze experiments devoted to that purpose. We demonstrate a high sensitivity of the laser Compton scattering at high energy accelerators to the effects of gravity. The main observable - maximal energy of the scattered photons - would experience a significant shift in the ambient gravitational field even for otherwise negligible violation of the equivalence principle. We confirm predictions of general relativity for ultrarelativistic electrons of energy of tens of GeV at a current level of resolution and expect our work to be a starting point of further high-precision studies on current and future accelerators, such as PETRA, European XFEL and ILC.

  4. [Attitudes toward psychotherapy in the general population].

    PubMed

    Petrowski, Katja; Hessel, Aike; Körner, Annett; Weidner, Kerstin; Brähler, Elmar; Hinz, Andreas

    2014-02-01

    Attitudes towards psychotherapy are important predictors for the acceptance and usage of psychotherapy. A survey examined attitudes towards psychotherapy in a sample representative of the German population including 2089 persons between 14 to 92 years of age. Two thirds of the sample indicated a positive attitude towards psychotherapy. Men as well as individuals with lower education reported a more negative attitude towards psychotherapy than women and persons with higher educational level. Education had a medium effect size (d=0.44). Individuals with somatoform symptoms did not indicate a more negative attitude towards psychotherapy than the general population. Even though the majority of the population has a more positive attitude towards psychotherapy, this positive attitude does not apply for all groups of the -population.

  5. Energy loss in general relativity

    NASA Astrophysics Data System (ADS)

    Cooperstock, F. I.; Lim, P. H.

    1987-07-01

    Implicit assumptions regarding continuity in energy-loss calculations in general relativity are examined. The Arnowitt-Deser-Misner energy integral is treated in a new manner as a universal vehicle for energy loss. Two explicit examples are given: the electric dipole radiation flux is computed using general relativity as well as the gravitational-radiation flux from a linear mass quadrupole oscillator. In this approach, the latter is seen as a nonlinear problem in the sense that the lower-order metric serves as a source for the required order metric as computed within the wave front. Logarithmic terms which threaten to induce divergences, as has been found in other works, are averted by functions of integration which are required to sustain the gauge conditions and finally yield the usual fluxes.

  6. General Relativity and Spacetime Relationism.

    NASA Astrophysics Data System (ADS)

    Hoefer, Carl

    1992-01-01

    This dissertation takes up the project of showing that, in the context of the general theory of relativity (GTR), spacetime relationism is not a refuted or hopeless view, as many in the recent literature have maintained (John Earman, Michael Friedman, and others). Most of the challenges to the relationist view in General Relativity can be satisfactorily answered; in addition, the opposing absolutist and substantivalist views of spacetime can be shown to be problematic. The crucial burden for relationists concerned with GTR is to show that the realistic cosmological models, i.e. those that may be roughly accurate representations of our universe, satisfy Mach's ideas about the origin of inertia. This dissertation clears the way for and begins such a demonstration. After a brief discussion of the problem of the nature of spacetime and its history in the Introduction, chapters 2 and 3 provide conceptual analysis and criticism of contemporary philosophical arguments about relationism, absolutism, and particularly substantivalism. The current best arguments in favor of substantivalism are shown to be flawed, with the exception of the argument from inertial and metrical structure; and on this issue, it is shown that both relationism and substantivalism need to argue for modifications of GTR (restriction of its models to those with certain features) in order to have a non-trivial explanation of inertial and metrical structure. For relationists, a Machian account of the origin of inertia in some models of GTR is required. Chapter 4 demonstrates that such a Machian account is equivalent to the demand for a truly general relativity of motion. Chapter 5 explores the history of Einstein's commitment to Mach's ideas in his work on GTR. Through an examination of the history of Einstein's attempts to impose Machian constraints on the models of General Relativity, further insight into the nature of this problem is obtained, as are reasons to believe that the project is by no means

  7. General relativity in electrical engineering

    NASA Astrophysics Data System (ADS)

    Leonhardt, U.; Philbin, T. G.

    2007-05-01

    In electrical engineering metamaterials have been developed that offer unprecedented control over electromagnetic fields. Here we show that general relativity lends the theoretical tools for designing devices made of such versatile materials. We consider media that facilitate space-time transformations and include negative refraction. Our theory unifies the concepts operating behind the scenes of perfect invisibility devices, perfect lenses, the optical Aharonov-Bohm effect and electromagnetic analogs of the event horizon, and may lead to further applications.

  8. Discrete Hamiltonian for general relativity

    NASA Astrophysics Data System (ADS)

    Ziprick, Jonathan; Gegenberg, Jack

    2016-02-01

    Beginning from the Ashtekar formulation of general relativity, we derive a physical Hamiltonian written in terms of (classical) loop gravity variables. This is done by defining the gravitational fields within a complex of three-dimensional cells and imposing that curvature and torsion vanish within each cell. The resulting theory is holographic, with the bulk dynamics being captured completely by degrees of freedom living on cell boundaries. Quantization is readily obtainable by existing methods.

  9. Sgr A* and general relativity

    NASA Astrophysics Data System (ADS)

    Johannsen, Tim

    2016-06-01

    General relativity has been widely tested in weak gravitational fields but still stands largely untested in the strong-field regime. According to the no-hair theorem, black holes in general relativity depend only on their masses and spins and are described by the Kerr metric. Mass and spin are the first two multipole moments of the Kerr spacetime and completely determine all higher-order moments. The no-hair theorem and, hence, general relativity can be tested by measuring potential deviations from the Kerr metric affecting such higher-order moments. Sagittarius A* (Sgr A*), the supermassive black hole at the center of the Milky Way, is a prime target for precision tests of general relativity with several experiments across the electromagnetic spectrum. First, near-infrared (NIR) monitoring of stars orbiting around Sgr A* with current and new instruments is expected to resolve their orbital precessions. Second, timing observations of radio pulsars near the Galactic center may detect characteristic residuals induced by the spin and quadrupole moment of Sgr A*. Third, the event horizon telescope, a global network of mm and sub-mm telescopes, aims to study Sgr A* on horizon scales and to image the silhouette of its shadow cast against the surrounding accretion flow using very-long baseline interferometric (VLBI) techniques. Both NIR and VLBI observations may also detect quasiperiodic variability of the emission from the accretion flow of Sgr A*. In this review, I discuss our current understanding of the spacetime of Sgr A* and the prospects of NIR, timing, and VLBI observations to test its Kerr nature in the near future.

  10. Results from Numerical General Relativity

    NASA Technical Reports Server (NTRS)

    Baker, John G.

    2011-01-01

    For several years numerical simulations have been revealing the details of general relativity's predictions for the dynamical interactions of merging black holes. I will review what has been learned of the rich phenomenology of these mergers and the resulting gravitational wave signatures. These wave forms provide a potentially observable record of the powerful astronomical events, a central target of gravitational wave astronomy. Asymmetric radiation can produce a thrust on the system which may accelerate the single black hole resulting from the merger to high relative velocity.

  11. Gravitation. [Book on general relativity

    NASA Technical Reports Server (NTRS)

    Misner, C. W.; Thorne, K. S.; Wheeler, J. A.

    1973-01-01

    This textbook on gravitation physics (Einstein's general relativity or geometrodynamics) is designed for a rigorous full-year course at the graduate level. The material is presented in two parallel tracks in an attempt to divide key physical ideas from more complex enrichment material to be selected at the discretion of the reader or teacher. The full book is intended to provide competence relative to the laws of physics in flat space-time, Einstein's geometric framework for physics, applications with pulsars and neutron stars, cosmology, the Schwarzschild geometry and gravitational collapse, gravitational waves, experimental tests of Einstein's theory, and mathematical concepts of differential geometry.

  12. Characteristics of hyperacusis in the general population.

    PubMed

    Paulin, Johan; Andersson, Linus; Nordin, Steven

    2016-01-01

    There is a need for better understanding of various characteristics in hyperacusis in the general population. The objectives of the present study were to investigate individuals in the general population with hyperacusis regarding demographics, lifestyle, perceived general health and hearing ability, hyperacusis-specific characteristics and behavior, and comorbidity. Using data from a large-scale population-based questionnaire study, we investigated individuals with physician-diagnosed (n = 66) and self-reported (n = 313) hyperacusis in comparison to individuals without hyperacusis (n = 2995). High age, female sex, and high education were associated with hyperacusis, and that trying to avoid sound sources, being able to affect the sound environment, and having sough medical attention were common reactions and behaviors. Posttraumatic stress disorder, chronic fatigue syndrome, generalized anxiety disorder, depression, exhaustion, fibromyalgia, irritable bowel syndrome, migraine, hearing impairment, tinnitus, and back/joint/muscle disorders were comorbid with hyperacusis. The results provide ground for future study of these characteristic features being risk factors for development of hyperacusis and/or consequences of hyperacusis. PMID:27569405

  13. Modern Canonical Quantum General Relativity

    NASA Astrophysics Data System (ADS)

    Thiemann, Thomas

    2008-11-01

    Preface; Notation and conventions; Introduction; Part I. Classical Foundations, Interpretation and the Canonical Quantisation Programme: 1. Classical Hamiltonian formulation of general relativity; 2. The problem of time, locality and the interpretation of quantum mechanics; 3. The programme of canonical quantisation; 4. The new canonical variables of Ashtekar for general relativity; Part II. Foundations of Modern Canonical Quantum General Relativity: 5. Introduction; 6. Step I: the holonomy-flux algebra [P]; 7. Step II: quantum-algebra; 8. Step III: representation theory of [A]; 9. Step IV: 1. Implementation and solution of the kinematical constraints; 10. Step V: 2. Implementation and solution of the Hamiltonian constraint; 11. Step VI: semiclassical analysis; Part III. Physical Applications: 12. Extension to standard matter; 13. Kinematical geometrical operators; 14. Spin foam models; 15. Quantum black hole physics; 16. Applications to particle physics and quantum cosmology; 17. Loop quantum gravity phenomenology; Part IV. Mathematical Tools and their Connection to Physics: 18. Tools from general topology; 19. Differential, Riemannian, symplectic and complex geometry; 20. Semianalytical category; 21. Elements of fibre bundle theory; 22. Holonomies on non-trivial fibre bundles; 23. Geometric quantisation; 24. The Dirac algorithm for field theories with constraints; 25. Tools from measure theory; 26. Elementary introduction to Gel'fand theory for Abelean C* algebras; 27. Bohr compactification of the real line; 28. Operatir -algebras and spectral theorem; 29. Refined algebraic quantisation (RAQ) and direct integral decomposition (DID); 30. Basics of harmonic analysis on compact Lie groups; 31. Spin network functions for SU(2); 32. + Functional analytical description of classical connection dynamics; Bibliography; Index.

  14. Modern Canonical Quantum General Relativity

    NASA Astrophysics Data System (ADS)

    Thiemann, Thomas

    2007-09-01

    Preface; Notation and conventions; Introduction; Part I. Classical Foundations, Interpretation and the Canonical Quantisation Programme: 1. Classical Hamiltonian formulation of general relativity; 2. The problem of time, locality and the interpretation of quantum mechanics; 3. The programme of canonical quantisation; 4. The new canonical variables of Ashtekar for general relativity; Part II. Foundations of Modern Canonical Quantum General Relativity: 5. Introduction; 6. Step I: the holonomy-flux algebra [P]; 7. Step II: quantum-algebra; 8. Step III: representation theory of [A]; 9. Step IV: 1. Implementation and solution of the kinematical constraints; 10. Step V: 2. Implementation and solution of the Hamiltonian constraint; 11. Step VI: semiclassical analysis; Part III. Physical Applications: 12. Extension to standard matter; 13. Kinematical geometrical operators; 14. Spin foam models; 15. Quantum black hole physics; 16. Applications to particle physics and quantum cosmology; 17. Loop quantum gravity phenomenology; Part IV. Mathematical Tools and their Connection to Physics: 18. Tools from general topology; 19. Differential, Riemannian, symplectic and complex geometry; 20. Semianalytical category; 21. Elements of fibre bundle theory; 22. Holonomies on non-trivial fibre bundles; 23. Geometric quantisation; 24. The Dirac algorithm for field theories with constraints; 25. Tools from measure theory; 26. Elementary introduction to Gel'fand theory for Abelean C* algebras; 27. Bohr compactification of the real line; 28. Operatir -algebras and spectral theorem; 29. Refined algebraic quantisation (RAQ) and direct integral decomposition (DID); 30. Basics of harmonic analysis on compact Lie groups; 31. Spin network functions for SU(2); 32. + Functional analytical description of classical connection dynamics; Bibliography; Index.

  15. Exposure of the general population to gasoline.

    PubMed Central

    Akland, G G

    1993-01-01

    This paper summarizes the currently available information on gasoline exposure to the general population. In general, the largest contribution to the time weighted exposures results from exposures while indoors, which are influenced by the outside air, indoor sources, and attached garages. Personal activities, including refueling and commuting, contribute significantly higher exposures but last for only a small portion of the 24-hr time weighted average. The highest exposed group includes those individuals living near large service stations and those with contaminated water supplies. PMID:8020446

  16. General relativity in electrical engineering

    NASA Astrophysics Data System (ADS)

    Leonhardt, Ulf; Philbin, Thomas G.

    2006-10-01

    In electrical engineering metamaterials have been developed that offer unprecedented control over electromagnetic fields. Here, we show that general relativity provides the theoretical tools for designing devices made of such versatile materials. Given a desired device function, the theory describes the electromagnetic properties that turn this function into fact. We consider media that facilitate space-time transformations and include negative refraction. Our theory unifies the concepts operating behind the scenes of perfect invisibility devices, perfect lenses, the optical Aharonov Bohm effect and electromagnetic analogues of the event horizon, and may lead to further applications.

  17. Dimensional Analysis and General Relativity

    NASA Astrophysics Data System (ADS)

    Lovatt, Ian

    2009-02-01

    Newton's law of gravitation is a central topic in the first-year physics curriculum. A lecturer can go beyond the physical details and use the history of gravitation to discuss the development of scientific ideas; unfortunately, the most recent chapter in this history, general relativity, is not covered in first-year courses. This paper discusses some topics that can be introduced with the judicious use of the dimensionless quantity GM/Rc2: deflection of light by a massive object, perihelion precession, gravitational redshifts, and the Global Positioning System (GPS).

  18. Spacecraft Tests of General Relativity

    NASA Technical Reports Server (NTRS)

    Anderson, John D.

    1997-01-01

    Current spacecraft tests of general relativity depend on coherent radio tracking referred to atomic frequency standards at the ground stations. This paper addresses the possibility of improved tests using essentially the current system, but with the added possibility of a space-borne atomic clock. Outside of the obvious measurement of the gravitational frequency shift of the spacecraft clock, a successor to the suborbital flight of a Scout D rocket in 1976 (GP-A Project), other metric tests would benefit most directly by a possible improved sensitivity for the reduced coherent data. For purposes of illustration, two possible missions are discussed. The first is a highly eccentric Earth orbiter, and the second a solar-conjunction experiment to measure the Shapiro time delay using coherent Doppler data instead of the conventional ranging modulation.

  19. A Generalized Detailed Balance Relation

    NASA Astrophysics Data System (ADS)

    Ruelle, David

    2016-08-01

    Given a system M in a thermal bath we obtain a generalized detailed balance relation for the ratio r=π _τ (K→ J)/π _τ (J→ K) of the transition probabilities M:J→ K and M:K→ J in time τ . We assume an active bath, containing solute molecules in metastable states. These molecules may react with M and the transition J→ K occurs through different channels α involving different reactions with the bath. We find that r=sum p^α r^α , where p^α is the probability that channel α occurs, and r^α depends on the amount of heat (more precisely enthalpy) released to the bath in channel α.

  20. Population characteristics and the distribution of general medical practitioners.

    PubMed Central

    Buxton, M J; Klein, R E

    1979-01-01

    By applying the logic of the Resource Allocation Working Party to the analysis of the distribution of general medical practitioners, the relevant Family Practitioner Committee (FPC) populations were weighted according to known patterns of use related to specific characteristics--namely, age, sex, marital state, and socioeconomic group. Comparative weightings were also calculated using standardised mortality ratios. Adjusting the populations to take account of differential use has relatively little impact on national variations in list sizes but an appreciable effect on particular FPCs, notably East and West Sussex, Dorset, and the Isle of Wight. Inequalities in the distribution of general practitioners are increased considerably, however, if figures taking account of the inflation of list sizes and cross-boundary flows are used. To formulate and monitor policy about the distribution of general practitioners more sensitive measures of population and its likely demand for services must be developed. PMID:427409

  1. Asbestos-related radiographic changes by ILO classification of 10 x 10 cm chest X-rays in a screening of the general population.

    PubMed

    Hilt, B; Hillerdal, G; Lund-Larsen, P G; Lien, J T; Langård, S

    1995-02-01

    A sample of 1388 10 x 10 cm chest X-rays from a previous population screening of males aged 40+ years were reevaluated by use of the ILO classification. There were 1036 films of subjects from an industrialized town, and 352 from a rural community. The observed rates of parenchymal changes (profusion > or = 1/0) at the reevaluation were 1.3% in the urban community and 3.4% in the rural community. The corresponding figures for pleural changes were 5.0% and 0.6%, respectively. Based on additional questionnaire information on asbestos exposure, it was found that the radiographic changes were probably related to past asbestos exposure for 2.3% of the subjects from the urban community and 0.6% from the rural community. In cases of asbestos-related illnesses the mean time since first exposure to asbestos was 35.9 years, whereas the mean duration of the exposures was 11.4 years. The results seem to indicate that the ILO reassessment of the radiographs was more sensitive in detecting pleural changes than the previous clinical screening of both small and large films.

  2. Oral hygiene status in a general population of Iran, 2011: a key lifestyle marker in relation to common risk factors of non-communicable diseases

    PubMed Central

    Asgari, Fereshteh; Majidi, Azam; Koohpayehzadeh, Jalil; Etemad, Koorosh; Rafei, Ali

    2015-01-01

    Background: To estimate Oral Hygiene (OH) status in the Iranian population in 2011, and to determine the influence of socio-economic characteristics on OH, and its interrelation with common risk factors of Non-Communicable Diseases (NCDs). Methods: Data including a total of 12,105 individuals aged 6-70 years were obtained from the sixth round of the surveys of NCDs risk factors in Iran. OH was recorded through a structured questionnaire measuring daily frequencies of tooth brushing and dental flossing. Descriptive analyses were performed on demographic characteristics in the complex sample survey setting. We also employed weighted binary logistic regression to compute Odds Ratio (OR) as a measure of association between the response and explanatory factors. Furthermore, to construct an asset index, we utilized Principal Component Analysis (PCA). Results: The percentage with minimum recommended daily OH practices was 3.7% among men and 7.7% among women (OR= 2.3; P< 0.001). Urban citizens were more likely to have their teeth cleaned compared to rural people (OR= 2.8; P< 0.001). For both genders, a relatively better condition was observed in the 25–34 age group (male: 5.6%; female: 10.3%). In addition, OH status improved significantly by increase in both level of education (P< 0.001) and economic status (P< 0.001). There were also apparent associations between self-care practices and specific behavioral risk factors, though the correlation with dietary habits and tobacco use could be largely explained by socio-economic factors. Conclusion: OH situation in Iran calls for urgent need to assign proper interventions and strategies toward raising public awareness and reducing disparities in access to health facilities. PMID:26029893

  3. Association between Body Mass Index and Health-Related Quality of Life: The "Obesity Paradox" in 21,218 Adults of the Chinese General Population

    PubMed Central

    Zhu, Yanbo; Wang, Qi; Pang, Guoming; Lin, Lin; Origasa, Hideki; Wang, Yangyang; Di, Jie; Shi, Mai; Fan, Chunpok; Shi, Huimei

    2015-01-01

    Background There was no consistent recognition of the association between high or low body mass index (BMI) and health related quality of life (HRQL). The aim of this research was to study the association between BMI and HRQL in Chinese adults, and to further explore the stability of that association in the subgroup analysis stratified by status of chronic conditions. Methods A total of 21,218 adults aged 18 and older were classified as underweight, normal weight, overweight, class I obese, and class II obese based on their BMI. HRQL was measured by the SF-36 Health Survey. The independent impact of each BMI category on HRQL was examined through standard least squares regression by comparing the difference of SF-36 scores and the minimum clinically important differences (MCID), which was defined as 3 points. Results Compared to the normal weight, the class I obese was significantly associated with better HRQL scores in the mental component summary (MCS) (75.1 vs. 73.4, P<0.001). The underweight had the lowest score in both the physical components summary (PCS) (75.4 vs. 77.5, P<0.001) and mental components summary (MCS) (71.8 vs. 73.4, P<0.001). For the MCID, the HRQL score was reduced by more than 3 points in the physical functioning for the class II obese (D=-3.43) and the general health for the underweight (D=-3.71). Stratified analyses showed a similar result in the health subjects and chronic conditions, and it was significant in the chronic conditions. Conclusions The class I obese showed the best HRQL, especially in the mental domain. The worst HRQL was found in the underweight. The class II obese reduced HRQL in the physical functioning only. “Obesity paradox” was more obvious in the participants with chronic conditions. PMID:26087128

  4. On superpotentials in general relativity

    NASA Astrophysics Data System (ADS)

    Stolín, Oldřich; Novotný, Jan

    2001-10-01

    It is shown that the Einstein—Freud, Landau—Lifshitz and Møller tetrad super-potentials represent special cases of a more general construction. The tetrad version of the Landau—Lifshitz superpotential is derived.

  5. Fourth order deformed general relativity

    NASA Astrophysics Data System (ADS)

    Cuttell, Peter D.; Sakellariadou, Mairi

    2014-11-01

    Whenever the condition of anomaly freedom is imposed within the framework of effective approaches to loop quantum cosmology, one seems to conclude that a deformation of general covariance is required. Here, starting from a general deformation we regain an effective gravitational Lagrangian including terms up to fourth order in extrinsic curvature. We subsequently constrain the form of the corrections for the homogeneous case, and then investigate the conditions for the occurrence of a big bounce and the realization of an inflationary era, in the presence of a perfect fluid or scalar field.

  6. Uniform acceleration in general relativity

    NASA Astrophysics Data System (ADS)

    Friedman, Yaakov; Scarr, Tzvi

    2015-10-01

    We extend de la Fuente and Romero's (Gen Relativ Gravit 47:33, 2015) defining equation for uniform acceleration in a general curved spacetime from linear acceleration to the full Lorentz covariant uniform acceleration. In a flat spacetime background, we have explicit solutions. We use generalized Fermi-Walker transport to parallel transport the Frenet basis along the trajectory. In flat spacetime, we obtain velocity and acceleration transformations from a uniformly accelerated system to an inertial system. We obtain the time dilation between accelerated clocks. We apply our acceleration transformations to the motion of a charged particle in a constant electromagnetic field and recover the Lorentz-Abraham-Dirac equation.

  7. Action principle for the generalized harmonic formulation of general relativity

    SciTech Connect

    Brown, J. David

    2011-10-15

    An action principle for the generalized harmonic formulation of general relativity is presented. The action is a functional of the spacetime metric and the gauge source vector. An action principle for the Z4 formulation of general relativity has been proposed recently by Bona, Bona-Casas, and Palenzuela. The relationship between the generalized harmonic action and the Bona, Bona-Casas, and Palenzuela action is discussed in detail.

  8. Human population variability in relative dental development.

    PubMed

    Tompkins, R L

    1996-01-01

    Using dental X-rays, the calcification of various teeth was compared between samples of black southern Africans, white French-Canadians, and prehistoric Native Americans sharing the same stage of calcification of a specified "reference tooth." The French-Canadians have markedly delayed relative development of the M3 compared to the Africans. They also appear delayed in their M2 development compared to both the Africans and Amerindians. While no difference in relative mandibular canine development is found between the African and French-Canadian males, French-Canadian females are advanced over the African females. Prehistoric Native Americans may be delayed in mandibular central incisor development compared to French-Canadians. These results are in general accord with other studies of variability in dental development between Africans/African Americans, Europeans/European Americans, and Native Americans, and demonstrate that population differences in ages of eruption are attributable in part to differences in relative dental development. Two potentially falsifiable hypotheses concerning the significance of population variability in relative dental development are discussed: 1) the variability (at least for molars) is associated with the amount of space in the jaws for developing teeth, 2) the variability is due to population differences in the timing of dental and skeletal development.

  9. Hamiltonian formulation of general relativity.

    NASA Astrophysics Data System (ADS)

    Teitelboim, Claudio

    The following sections are included: * INTRODUCTION * HAMILTONIAN FORMULATION OF GAUGE THEORIES (PRE-BRST) * BRST HAMILTONIAN FORMULATION OF GAUGE THEORIES * DYNAMICS OF GRAVITATIONAL FIELD * DOES THE HAMILTONIAN VANISH? GENERAL COVARIANCE AS AN "ORDINARY" GAUGE INVARIANCE * GENERALLY COVARIANT SYSTEMS * TIME AS A CANONICAL VARIABLE. ZERO HAMILTONIAN * Parametrized Systems * Zero Hamiltonian * Parametrization and Explicit Time Dependence * TIME REPARAMETRIZATION INVARIANCE * Form of Gauge Transformations * Must the Hamiltonian be Zero for a Generally Covariant System? * Simple Example of a Generally Covariant System with a Nonzero Hamiltonian * "TRUE DYNAMICS" VERSUS GAUGE TRANSFORMATIONS * Interpretation of the Formalism * Reduced Phase Space * MUST TIME FLOW? * GAUGE INDEPENDENCE OF PATH INTEGRAL FOR A PARAMETRIZED SYSTEM ILLUSTRATED. EQUIVALENCE OF THE GAUGES t = τ AND t = 0 * Reduced Phase Space Transition Amplitude as a Reduced Phase Space Path Integral * Canonical Gauge Conditions * Gauge t = 0 * Gauge t α τ * BRST CHARGE OF GRAVITATIONAL FIELD * ELEMENTS OF BRST THEORY * THE GHOST, YOU'VE COME A LONG WAY BABY * Introduction * Quantum mechanics, the art of finding and combining simple elementary processes * Ghosts necessary to keep elementary processes simple * BRST symmetry: ghosts and matter become different components of single geometrical object * BRST SYMMETRY IN CLASSICAL MECHANICS * Ghosts have role in classical mechanics * Gauge invariance and constraints * Classical mechanics over Grassmann algebra necessary * Higher order structure functions * Rank defined. Open algebras * Ghosts. Ghost number. BRST generator as generating function for structure functions * A belianization of constraints. Existence of Ω * Uniqueness of Ω * Classical BRST cohomology * QUANTUM BRST THEORY * States and operators * Ghost number * BRST invariant states * Quantum BRST cohomology * Equivalence of the BRST physical subspace with the conventional gauge

  10. Quasilocal mass in general relativity.

    PubMed

    Wang, Mu-Tao; Yau, Shing-Tung

    2009-01-16

    There have been many attempts to define the notion of quasilocal mass for a spacelike two surface in spacetime by the Hamilton-Jacobi analysis. The essential difficulty in this approach is to identify the right choice of the background configuration to be subtracted from the physical Hamiltonian. Quasilocal mass should be non-negative for surfaces in general spacetime and zero for surfaces in flat spacetime. In this Letter, we propose a new definition of gauge-independent quasilocal mass and prove that it has the desired properties. PMID:19257261

  11. General relativity and satellite orbits

    NASA Technical Reports Server (NTRS)

    Rubincam, D. P.

    1975-01-01

    The general relativistic correction to the position of a satellite is found by retaining Newtonian physics for an observer on the satellite and introducing a potential. The potential is expanded in terms of the Keplerian elements of the orbit and substituted in Lagrange's equations. Integration of the equations shows that a typical earth satellite with small orbital eccentricity is displaced by about 17 cm. from its unperturbed position after a single orbit, while the periodic displacement over the orbit reaches a maximum of about 3 cm. The moon is displaced by about the same amounts. Application of the equations to Mercury gives a total displacement of about 58 km. after one orbit and a maximum periodic displacement of about 12 km.

  12. Pulsar timing and general relativity

    NASA Technical Reports Server (NTRS)

    Backer, D. C.; Hellings, R. W.

    1986-01-01

    Techniques are described for accounting for relativistic effects in the analysis of pulsar signals. Design features of instrumentation used to achieve millisecond accuracy in the signal measurements are discussed. The accuracy of the data permits modeling the pulsar physical characteristics from the natural glitches in the emissions. Relativistic corrections are defined for adjusting for differences between the pulsar motion in its spacetime coordinate system relative to the terrestrial coordinate system, the earth's motion, and the gravitational potentials of solar system bodies. Modifications of the model to allow for a binary pulsar system are outlined, including treatment of the system as a point mass. Finally, a quadrupole model is presented for gravitational radiation and techniques are defined for using pulsars in the search for gravitational waves.

  13. Screening and triage of intrauterine growth restriction (IUGR) in general population and high risk pregnancies: a systematic review with a focus on reduction of IUGR related stillbirths

    PubMed Central

    2011-01-01

    Background There is a strong association between stillbirth and fetal growth restriction. Early detection and management of IUGR can lead to reduce related morbidity and mortality. In this paper we have reviewed effectiveness of fetal movement monitoring and Doppler velocimetry for the detection and surveillance of high risk pregnancies and the effect of this on prevention of stillbirths. We have also reviewed effect of maternal body mass index (BMI) screening, symphysial-fundal height measurement and targeted ultrasound in detection and triage of IUGR in the community. Methods We systematically reviewed all published literature to identify studies related to our interventions. We searched PubMed, Cochrane Library, and all World Health Organization Regional Databases and included publications in any language. Quality of available evidence was assessed using GRADE criteria. Recommendations were made for the Lives Saved Tool (LiST) based on rules developed by the Child Health Epidemiology Group. Given the paucity of evidence related to the effect of detection and management of IUGR on stillbirths, we undertook Delphi based evaluation from experts in the field. Results There was insufficient evidence to recommend against or in favor of routine use of fetal movement monitoring for fetal well being. (1) Detection and triage of IUGR with the help of (1a) maternal BMI screening, (1b) symphysial-fundal height measurement and (1c) targeted ultrasound can be an effective method of reducing IUGR related perinatal morbidity and mortality. Pooled results from sixteen studies shows that Doppler velocimetry of umbilical and fetal arteries in ‘high risk’ pregnancies, coupled with the appropriate intervention, can reduce perinatal mortality by 29 % [RR 0.71, 95 % CI 0.52-0.98]. Pooled results for impact on stillbirth showed a reduction of 35 % [RR 0.65, 95 % CI 0.41-1.04]; however, the results did not reach the conventional limits of statistical significance. This intervention

  14. Age-related changes in the distributions of depressive symptom items in the general population: a cross-sectional study using the exponential distribution model.

    PubMed

    Tomitaka, Shinichiro; Kawasaki, Yohei; Ide, Kazuki; Yamada, Hiroshi; Furukawa, Toshiaki A; Ono, Yutaka

    2016-01-01

    Background. Previous research has reported inconsistent evidence of the trajectory of depressive symptoms across the adult lifespan. We investigated how the distributions of each item score change with age and determined whether the trajectory of depressive symptoms varied with the scoring methods of the questionnaire. Methods. We analyzed data collected from 21,040 subjects who participated in the national survey in Japan. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale (CES-D). The CES-D has 20 items, each of which is scored in four grades of "rarely," "some," "much," and "most of the time." We used the exponential distribution model which fits the distributions of 16 negative symptom items of CES-D, with the probabilities of "some," "much," "most," and "rarely" expressed as P, Pr, Pr (2), and 1 - P × (r (2) + r + 1). Results. The distributions of the responses to 16 negative symptom items followed the common exponential model across all age groups. The mean of the estimated parameter r of 16 negative items showed a U-shape pattern, being high during 12-29 years, remaining low during 30-50 years, and then increasing again over 60 years. The trajectory of depressive symptom scores simulating the binary method was different from that of the empirical scores using the Likert method. Conclusions. Our findings show that the increase in the depressive symptoms score during older age is based on the increase of the parameter r. The differences in the scoring method may contribute to the different age-related patterns across the adult lifespan. PMID:26788427

  15. Social integration of juvenile amputees: comparison with a general population.

    PubMed

    Fernández, A; Revilla, C; Su, I-Ting; García, M

    2003-04-01

    The objective was to assess the social integration of juvenile amputees according to marital status, schooling and occupation, and to compare it with the population of Asturias, Spain. A retrospective study was carried out of the juvenile amputees registered from 1976 to 1999 at the Prosthetics Unit of the Asturias Central Hospital (n=281 amputees). The proportion of single women amongst the amputees was greater than in the population of Asturias (p<0.05). Amongst the male amputees, relative to the general population, there was a larger proportion of the group with primary studies (p<0.001) and a smaller proportion with secondary studies (p<0.001). At the higher level (university) there were no differences, either in men or in women. As regards occupation, amongst the amputees a larger number was found who were retired or unemployed (p<0.05 and p<0.001). In conclusion, juvenile amputees do not show differences compared to the general population with regard to their attendance at a higher or university level of education. However, if their social integration is considered through occupation, male amputees show a greater proportion of unemployment, which is a clear reflection of their handicap. PMID:12812323

  16. Social integration of juvenile amputees: comparison with a general population.

    PubMed

    Fernández, A; Revilla, C; Su, I-Ting; García, M

    2003-04-01

    The objective was to assess the social integration of juvenile amputees according to marital status, schooling and occupation, and to compare it with the population of Asturias, Spain. A retrospective study was carried out of the juvenile amputees registered from 1976 to 1999 at the Prosthetics Unit of the Asturias Central Hospital (n=281 amputees). The proportion of single women amongst the amputees was greater than in the population of Asturias (p<0.05). Amongst the male amputees, relative to the general population, there was a larger proportion of the group with primary studies (p<0.001) and a smaller proportion with secondary studies (p<0.001). At the higher level (university) there were no differences, either in men or in women. As regards occupation, amongst the amputees a larger number was found who were retired or unemployed (p<0.05 and p<0.001). In conclusion, juvenile amputees do not show differences compared to the general population with regard to their attendance at a higher or university level of education. However, if their social integration is considered through occupation, male amputees show a greater proportion of unemployment, which is a clear reflection of their handicap.

  17. General Information about AIDS-Related Lymphoma

    MedlinePlus

    ... AIDS-Related Lymphoma Treatment (PDQ®)–Patient Version General Information About AIDS-Related Lymphoma Go to Health Professional ... the PDQ Adult Treatment Editorial Board . Clinical Trial Information A clinical trial is a study to answer ...

  18. A general consumer-resource population model

    USGS Publications Warehouse

    Lafferty, Kevin D.; DeLeo, Giulio; Briggs, Cheryl J.; Dobson, Andrew P.; Gross, Thilo; Kuris, Armand M.

    2015-01-01

    Food-web dynamics arise from predator-prey, parasite-host, and herbivore-plant interactions. Models for such interactions include up to three consumer activity states (questing, attacking, consuming) and up to four resource response states (susceptible, exposed, ingested, resistant). Articulating these states into a general model allows for dissecting, comparing, and deriving consumer-resource models. We specify this general model for 11 generic consumer strategies that group mathematically into predators, parasites, and micropredators and then derive conditions for consumer success, including a universal saturating functional response. We further show how to use this framework to create simple models with a common mathematical lineage and transparent assumptions. Underlying assumptions, missing elements, and composite parameters are revealed when classic consumer-resource models are derived from the general model.

  19. General Relativity in (1 + 1) Dimensions

    ERIC Educational Resources Information Center

    Boozer, A. D.

    2008-01-01

    We describe a theory of gravity in (1 + 1) dimensions that can be thought of as a toy model of general relativity. The theory should be a useful pedagogical tool, because it is mathematically much simpler than general relativity but shares much of the same conceptual structure; in particular, it gives a simple illustration of how gravity arises…

  20. Event-Specific Drinking in the General Population

    PubMed Central

    Kushnir, Vladyslav; Cunningham, John Alastair

    2014-01-01

    Objective: It has been well established that college students engage in heavy drinking during specific social events; however, within the general population, evidence of event-specific drinking has been largely indirect. The present study therefore aimed to investigate the temporal variability in daily alcohol consumption in the winter holiday months among residents of a large metropolitan area. Method: A random-digit-dialing telephone survey was conducted of residents who drank alcohol at least once per month. During a 5-week period beginning December 1, 2009, the number of drinks consumed on each day within the past week was collected for 578 participants. Results: Weekly variation in alcohol consumption peaked on Fridays and Saturdays and was particularly high on Christmas and New Year’s Eve. Mean drink consumption was significantly higher on Christmas and New Year’s Eve compared with most weekends within the sampling period. Conclusions: The present findings provide the first direct evidence, with temporal specificity, that alcohol consumption within the general population is highly event specific. Targeted intervention strategies similar to those used within college student samples may be appropriate for reducing or preventing alcohol-related harmful events on a population level. PMID:25343654

  1. The Confrontation between General Relativity and Experiment

    NASA Astrophysics Data System (ADS)

    Will, Clifford M.

    2001-12-01

    The status of experimental tests of general relativity and of theoretical frameworks for analysing them are reviewed. Einstein’s equivalence principle (EEP) is well supported by experiments such as the Eötvös experiment, tests of special relativity, and the gravitational redshift experiment. Future tests of EEP and of the inverse square law will search for new interactions arising from unification or quantum gravity. Tests of general relativity at the post-Newtonian level have reached high precision, including the light defl ection the Shapiro time delay, the perihelion advance of Mercury, and the Nordtvedt effect in lunar motion. Gravitational wave damping has been detected in an amount that agrees with general relativity to half a percent using the Hulse-Taylor binary pulsar, and new binary pulsar systems may yield further improvements. When direct observation of gravitational radiation from astrophysical sources begins, new tests of general relativity will be possible.

  2. Einstein and General Relativity: Historical Perspectives.

    ERIC Educational Resources Information Center

    Chandrasekhar, S.

    1979-01-01

    This paper presented in the 1978 Oppenheimer Memorial Lecture at Los Alamos Scientific Laboratories on August 17, 1978, discusses Einstein's contributions to physics, in particular, his discovery of the general theory of relativity. (HM)

  3. Recovering General Relativity from Massive Gravity

    SciTech Connect

    Babichev, E.; Deffayet, C.; Ziour, R.

    2009-11-13

    We obtain static, spherically symmetric, and asymptotically flat numerical solutions of massive gravity with a source. Those solutions show, for the first time explicitly, a recovery of the Schwarzschild solution of general relativity via the so-called Vainshtein mechanism.

  4. Teaching General Relativity to the Layperson

    ERIC Educational Resources Information Center

    Egdall, Mark

    2009-01-01

    This paper describes a lay course on general relativity (GR) given at the Osher Lifelong Learning Institute at Florida International University. It is presented in six hour-and-a-half weekly sessions. Other courses offered by the author include special relativity (which precedes the course described here), quantum theory, and cosmology. Students…

  5. Black hole based tests of general relativity

    NASA Astrophysics Data System (ADS)

    Yagi, Kent; Stein, Leo C.

    2016-03-01

    General relativity has passed all solar system experiments and neutron star based tests, such as binary pulsar observations, with flying colors. A more exotic arena for testing general relativity is in systems that contain one or more black holes. Black holes are the most compact objects in the Universe, providing probes of the strongest-possible gravitational fields. We are motivated to study strong-field gravity since many theories give large deviations from general relativity only at large field strengths, while recovering the weak-field behavior. In this article, we review how one can probe general relativity and various alternative theories of gravity by using electromagnetic waves from a black hole with an accretion disk, and gravitational waves from black hole binaries. We first review model-independent ways of testing gravity with electromagnetic/gravitational waves from a black hole system. We then focus on selected examples of theories that extend general relativity in rather simple ways. Some important characteristics of general relativity include (but are not limited to) (i) only tensor gravitational degrees of freedom, (ii) the graviton is massless, (iii) no quadratic or higher curvatures in the action, and (iv) the theory is four-dimensional. Altering a characteristic leads to a different extension of general relativity: (i) scalar-tensor theories, (ii) massive gravity theories, (iii) quadratic gravity, and (iv) theories with large extra dimensions. Within each theory, we describe black hole solutions, their properties, and current and projected constraints on each theory using black hole based tests of gravity. We close this review by listing some of the open problems in model-independent tests and within each specific theory.

  6. General very special relativity in Finsler cosmology

    SciTech Connect

    Kouretsis, A. P.; Stathakopoulos, M.; Stavrinos, P. C.

    2009-05-15

    General very special relativity (GVSR) is the curved space-time of very special relativity (VSR) proposed by Cohen and Glashow. The geometry of general very special relativity possesses a line element of Finsler geometry introduced by Bogoslovsky. We calculate the Einstein field equations and derive a modified Friedmann-Robertson-Walker cosmology for an osculating Riemannian space. The Friedmann equation of motion leads to an explanation of the cosmological acceleration in terms of an alternative non-Lorentz invariant theory. A first order approach for a primordial-spurionic vector field introduced into the metric gives back an estimation of the energy evolution and inflation.

  7. General Relativity Theory: Recognition through Time

    NASA Astrophysics Data System (ADS)

    Alexandrov, A. N.; Vavilova, I. B.; Zhdanov, V. I.; Zhuk, A. I.; Kudrya, Yu. N.; Parnovsky, S. L.; Fedorova, E. V.; Yatskiv, Ya. S.

    2015-10-01

    The book provides an overview of the current state of the General Relativity Theory on the eve of its centennial. The authors describe briefly the basis of this theory, systematize experimental verifications and outline the main areas of its applications in astrophysics, cosmology and astrometry in the light of the last decade. For researchers and students specializing in the Relativity Theory as well as for anyone interested in Relativity Theory, relativistic astrophysics and cosmology.

  8. Testing General Relativity with Bursting Neutron Stars

    NASA Astrophysics Data System (ADS)

    Psaltis, Dimitrios

    2008-03-01

    Neutron stars offer the possibility of testing General Relativity in the highest possible curvature limit attainable by an astrophysical object. Such tests, however, are hampered by the lack of a theoretical framework with which potential deviations from the GR predictions can be quantified. I show that several observable properties of bursting neutron stars in metric theories of gravity can be calculated using only conservation laws, symmetries, and the Einstein equivalence principle, without requiring the validity of the general relativistic field equations. I discuss, in particular, the gravitational redshift of a surface atomic line, the touchdown luminosity of a radius-expansion burst, which is believed to be equal to the Eddington critical luminosity, and the apparent surface area of a neutron star as measured during the cooling tails of bursts. I show that, for a general metric theory of gravity, the apparent surface area of a neutron star depends on the coordinate radius of the stellar surface and on its gravitational redshift in the exact same way as in general relativity. On the other hand, the Eddington critical luminosity depends also on an additional parameter that measures the degree to which the general relativistic field equations are satisfied. These results can be used in conjunction with current and future high-energy observations of bursting neutron stars to test general relativity in the strong-field regime.

  9. Recent astronomical tests of general relativity

    NASA Astrophysics Data System (ADS)

    Keith John Treschman

    2015-01-01

    This history of experimentation relevant to general relativity covers the time post-1928. Classes of investigation are the weak equivalence principle (equivalence of inertial and gravitational mass and gravitational redshift), orbital precession of a body in gravitational fields (the relativistic perihelion advance of the planets, the relativistic periastron advance of binary pulsars, geodetic precession and Lense-Thirring effect), light propagation in gravitational fields (gravitational optical light deflection, gravitational radio deflection due to the Sun, gravitational lensing, time dilation and atomic clocks) and strong gravity implications (Nordtved effect and potential gravitational waves). The results of experiments are analysed to conclude to what extent they support general relativity. A number of questions are then answered: (a) how much evidence exists to support general relativity, (b) is it a reasonable way of thinking and (c) what is the niche it may occupy?

  10. Risk factors for carpal tunnel syndrome in a general population.

    PubMed Central

    Nordstrom, D L; Vierkant, R A; DeStefano, F; Layde, P M

    1997-01-01

    OBJECTIVE: To determine the individual, physical, and psychosocial risk factors for carpal tunnel syndrome in a general population. METHODS: Population based case-control study in Marshfield epidemiological study area in Wisconsin, USA. Cases were men and women aged 18-69 with newly diagnosed carpal tunnel syndrome (n = 206 (83.1%) of 248 eligible). Controls were a random sample of residents of the study area who had no history of diagnosed carpal tunnel syndrome (n = 211 (81.5%) of 259 eligible). Cases and controls were matched by age. Telephone interviews and reviews of medical records obtained height and weight, medical history, average daily hours of exposure to selected physical and organisational work factors, and self ratings on psychosocial work scales. RESULTS: In the final logistic regression model, five work and three non-work variables were associated with risk of carpal tunnel syndrome, after adjusting for age. For each one unit of increase in body mass index (kg/m2), risk increased 8% (odds ratio (OR) 1.08; 95% confidence interval (95% CI) 1.03 to 1.14). Having a previous musculoskeletal condition was positively associated with carpal tunnel syndrome (OR 2.54; 95% CI 1.03 to 6.23). People reporting the least influence at work had 2.86 times the risk (95% CI, 1.10 to 7.14) than those with the most influence at work. CONCLUSIONS: Carpal tunnel syndrome is a work related disease, although some important measures of occupational exposure, including keyboard use, were not risk factors in this general population study. The mechanism whereby a weight gain of about six pounds increases the risk of disease 8% requires explanation. PMID:9404321

  11. Einstein and the history of general relativity

    SciTech Connect

    Howard, D.; Stachel, J.

    1989-01-01

    This book is a collection of essays by the authors and other people that deal with scientific opinions that led Einstein and his contemporaries to their views of general relativity. Some of the essays explore Einstein's passage from the special theory through a sequence of gravitational theories to the discovery of the field equations of the grand theory in November 1915. Two other essays discuss Einstein's public and private exchanges with Max Abraham and Tullio Levi-Civita in 1913 and 1914. A sympathetic picture of H.A. Lorentz's reaction to the general theory of relativity is included, and a careful and insightful essay on the early understanding of the Schwarzschild-Droste solution to the field equations of general relativity is presented. One paper presents a discussion on the state of the enterprise of general relativity between 1925 and 1928, and a short essay details the history of steps toward quantum gravitational through canonical quantization. A discussion of the history of derivations of the geodesic equation of motion from the field equation and conservation laws of the general theory is presented. The early history of geometrical unified field theories is included.

  12. Generalized Landau-Pollak uncertainty relation

    SciTech Connect

    Miyadera, Takayuki; Imai, Hideki

    2007-12-15

    The Landau-Pollak uncertainty relation treats a pair of rank one projection valued measures and imposes a restriction on their probability distributions. It gives a nontrivial bound for summation of their maximum values. We give a generalization of this bound (weak version of the Landau-Pollak uncertainty relation). Our generalization covers a pair of positive operator valued measures. A nontrivial but slightly weak inequality that can treat an arbitrary number of positive operator valued measures is also presented. A possible application to the problem of separability criterion is also suggested.

  13. Affine generalization of the Komar complex of general relativity

    NASA Astrophysics Data System (ADS)

    Mielke, Eckehard W.

    2001-02-01

    On the basis of the ``on shell'' Noether identities of the metric-affine gauge approach of gravity, an affine superpotential is derived which comprises the energy- and angular-momentum content of exact solutions. In the special case of general relativity (GR) or its teleparallel equivalent, the Komar or Freud complex, respectively, are recovered. Applying this to the spontaneously broken anti-de Sitter gauge model of McDowell and Mansouri with an induced Euler term automatically yields the correct mass and spin of the Kerr-AdS solution of GR with a (induced) cosmological constant without the factor two discrepancy of the Komar formula.

  14. Projective structure and holonomy in general relativity

    NASA Astrophysics Data System (ADS)

    Hall, G. S.; Lonie, D. P.

    2011-04-01

    This review presents a study of the situation when two spacetimes admit the same (unparametrized) geodesics, that is, when they are projectively related. The solution is based on the curvature class and the holonomy type of a spacetime and it transpires that all holonomy possibilities can be solved except the most general one and that the consequence of two spacetimes being projectively related leads, in many cases, to their associated Levi-Civita connections being identical. Some results are also given regarding the general case. It is also shown that the holonomy types of projectively related spacetimes are very closely related. The theory is then applied, with Einstein's principle of equivalence in mind, to 'generic' spacetimes.

  15. Tests of general relativity using pulsars

    NASA Technical Reports Server (NTRS)

    Reichley, P. E.

    1971-01-01

    The arrival times of the pulses from each pulsar are measured by a cesium clock. The observations are all made at a frequency of 2388 MHz (12.5 cm wavelength) on a 26 m dish antenna. The effect of interstellar charged particles is a random one that increases the noise level on the arrival time measurements. The variation in clock rate is shown consisting of two effects: the time dilation effect of special relativity and the red shift effect of general relativity.

  16. Diffusion in the general theory of relativity

    SciTech Connect

    Herrmann, Joachim

    2010-07-15

    The Markovian diffusion theory in the phase space is generalized within the framework of the general theory of relativity. The introduction of moving orthonormal frame vectors both for the position as well the velocity space avoids difficulties in the general relativistic stochastic calculus. The general relativistic Kramers equation in the phase space is derived both in the parametrization of phase-space proper time and the coordinate time. The transformation of the obtained diffusion equation under hypersurface-preserving coordinate transformations is analyzed and diffusion in the expanding universe is studied. It is shown that the validity of the fluctuation-dissipation theorem ensures that in the quasisteady state regime, the result of the derived diffusion equation is consistent with the kinetic theory in thermodynamic equilibrium.

  17. Generating perfect fluid spheres in general relativity

    NASA Astrophysics Data System (ADS)

    Boonserm, Petarpa; Visser, Matt; Weinfurtner, Silke

    2005-06-01

    Ever since Karl Schwarzschild’s 1916 discovery of the spacetime geometry describing the interior of a particular idealized general relativistic star—a static spherically symmetric blob of fluid with position-independent density—the general relativity community has continued to devote considerable time and energy to understanding the general-relativistic static perfect fluid sphere. Over the last 90 years a tangle of specific perfect fluid spheres has been discovered, with most of these specific examples seemingly independent from each other. To bring some order to this collection, in this article we develop several new transformation theorems that map perfect fluid spheres into perfect fluid spheres. These transformation theorems sometimes lead to unexpected connections between previously known perfect fluid spheres, sometimes lead to new previously unknown perfect fluid spheres, and in general can be used to develop a systematic way of classifying the set of all perfect fluid spheres.

  18. The detection rate of inspiral and quasi-normal modes of Population III binary black holes which can confirm or refute the general relativity in the strong gravity region

    NASA Astrophysics Data System (ADS)

    Kinugawa, Tomoya; Miyamoto, Akinobu; Kanda, Nobuyuki; Nakamura, Takashi

    2016-02-01

    Using our population synthesis code, we found that the typical chirp mass defined by (m1m2)3/5/(m1 + m2)1/5 of Population III (Pop III) binary black holes (BH-BHs) is ˜30 M⊙ with the total mass of ˜60 M⊙ so that the inspiral chirp signal as well as quasi-normal mode (QNM) of the merging black hole (BH) are interesting targets of KAGRA. The detection rate of the coalescing Pop III BH-BHs is ˜180 events yr- 1 (SFRp/(10-2.5 M⊙ yr-1 Mpc-3))([fb/(1 + fb)]/0.33)Errsys in our standard model, where SFRp, fb and Errsys are the peak value of the Pop III star formation rate, the binary fraction and the systematic error with Errsys = 1 for our standard model, respectively. To evaluate the robustness of chirp mass distribution and the range of Errsys, we examine the dependence of the results on the unknown parameters and the distribution functions in the population synthesis code. We found that the chirp mass has a peak at ˜30 M⊙ in most of parameters and distribution functions as well as Errsys ranges from 0.046 to 4. Therefore, the detection rate of the coalescing Pop III BH-BHs ranges about 8.3-720 events yr- 1(SFRp/(10- 2.5 M⊙ yr- 1 Mpc- 3))([fb/(1 + fb)]/0.33). The minimum rate corresponds to the worst model which we think unlikely so that unless (SFRp/(10- 2.5 M⊙ yr- 1 Mpc- 3))([fb/(1 + fb)]/0.33) ≪ 0.1, we expect the Pop III BH-BHs merger rate of at least one event per year by KAGRA. Nakano, Tanaka & Nakamura show that if signal-to-noise ratio (S/N) of QNM is larger than 35, we can confirm or refute the general relativity (GR) more than 5σ level. In our standard model, the detection rate of Pop III BH-BHs whose S/N is larger than 35 is 3.2 events yr- 1 (SFRp/(10- 2.5 M⊙ yr- 1 Mpc- 3))([fb/(1 + fb)]/0.33)Errsys. Thus, there is a good chance to check whether GR is correct or not in the strong gravity region.

  19. Tests of General Relativity with GW150914

    NASA Astrophysics Data System (ADS)

    Abbott, B. P.; Abbott, R.; Abbott, T. D.; Abernathy, M. R.; Acernese, F.; Ackley, K.; Adams, C.; Adams, T.; Addesso, P.; Adhikari, R. X.; Adya, V. B.; Affeldt, C.; Agathos, M.; Agatsuma, K.; Aggarwal, N.; Aguiar, O. D.; Aiello, L.; Ain, A.; Ajith, P.; Allen, B.; Allocca, A.; Altin, P. A.; Anderson, S. B.; Anderson, W. G.; Arai, K.; Araya, M. C.; Arceneaux, C. C.; Areeda, J. S.; Arnaud, N.; Arun, K. G.; Ascenzi, S.; Ashton, G.; Ast, M.; Aston, S. M.; Astone, P.; Aufmuth, P.; Aulbert, C.; Babak, S.; Bacon, P.; Bader, M. K. M.; Baker, P. T.; Baldaccini, F.; Ballardin, G.; Ballmer, S. W.; Barayoga, J. C.; Barclay, S. E.; Barish, B. C.; Barker, D.; Barone, F.; Barr, B.; Barsotti, L.; Barsuglia, M.; Barta, D.; Bartlett, J.; Bartos, I.; Bassiri, R.; Basti, A.; Batch, J. C.; Baune, C.; Bavigadda, V.; Bazzan, M.; Behnke, B.; Bejger, M.; Bell, A. S.; Bell, C. J.; Berger, B. K.; Bergman, J.; Bergmann, G.; Berry, C. P. L.; Bersanetti, D.; Bertolini, A.; Betzwieser, J.; Bhagwat, S.; Bhandare, R.; Bilenko, I. A.; Billingsley, G.; Birch, J.; Birney, R.; Birnholtz, O.; Biscans, S.; Bisht, A.; Bitossi, M.; Biwer, C.; Bizouard, M. A.; Blackburn, J. K.; Blair, C. D.; Blair, D. G.; Blair, R. M.; Bloemen, S.; Bock, O.; Bodiya, T. P.; Boer, M.; Bogaert, G.; Bogan, C.; Bohe, A.; Bojtos, P.; Bond, C.; Bondu, F.; Bonnand, R.; Boom, B. A.; Bork, R.; Boschi, V.; Bose, S.; Bouffanais, Y.; Bozzi, A.; Bradaschia, C.; Brady, P. R.; Braginsky, V. B.; Branchesi, M.; Brau, J. E.; Briant, T.; Brillet, A.; Brinkmann, M.; Brisson, V.; Brockill, P.; Brooks, A. F.; Brown, D. A.; Brown, D. D.; Brown, N. M.; Buchanan, C. C.; Buikema, A.; Bulik, T.; Bulten, H. J.; Buonanno, A.; Buskulic, D.; Buy, C.; Byer, R. L.; Cadonati, L.; Cagnoli, G.; Cahillane, C.; Calderón Bustillo, J.; Callister, T.; Calloni, E.; Camp, J. B.; Cannon, K. C.; Cao, J.; Capano, C. D.; Capocasa, E.; Carbognani, F.; Caride, S.; Casanueva Diaz, J.; Casentini, C.; Caudill, S.; Cavaglià, M.; Cavalier, F.; Cavalieri, R.; Cella, G.; Cepeda, C. B.; Cerboni Baiardi, L.; Cerretani, G.; Cesarini, E.; Chakraborty, R.; Chalermsongsak, T.; Chamberlin, S. J.; Chan, M.; Chao, S.; Charlton, P.; Chassande-Mottin, E.; Chen, H. Y.; Chen, Y.; Cheng, C.; Chincarini, A.; Chiummo, A.; Cho, H. S.; Cho, M.; Chow, J. H.; Christensen, N.; Chu, Q.; Chua, S.; Chung, S.; Ciani, G.; Clara, F.; Clark, J. A.; Cleva, F.; Coccia, E.; Cohadon, P.-F.; Colla, A.; Collette, C. G.; Cominsky, L.; Constancio, M.; Conte, A.; Conti, L.; Cook, D.; Corbitt, T. R.; Cornish, N.; Corsi, A.; Cortese, S.; Costa, C. A.; Coughlin, M. W.; Coughlin, S. B.; Coulon, J.-P.; Countryman, S. T.; Couvares, P.; Cowan, E. E.; Coward, D. M.; Cowart, M. J.; Coyne, D. C.; Coyne, R.; Craig, K.; Creighton, J. D. E.; Cripe, J.; Crowder, S. G.; Cumming, A.; Cunningham, L.; Cuoco, E.; Dal Canton, T.; Danilishin, S. L.; D'Antonio, S.; Danzmann, K.; Darman, N. S.; Dattilo, V.; Dave, I.; Daveloza, H. P.; Davier, M.; Davies, G. S.; Daw, E. J.; Day, R.; DeBra, D.; Debreczeni, G.; Degallaix, J.; De Laurentis, M.; Deléglise, S.; Del Pozzo, W.; Denker, T.; Dent, T.; Dereli, H.; Dergachev, V.; De Rosa, R.; DeRosa, R. T.; DeSalvo, R.; Dhurandhar, S.; Díaz, M. C.; Di Fiore, L.; Di Giovanni, M.; Di Lieto, A.; Di Pace, S.; Di Palma, I.; Di Virgilio, A.; Dojcinoski, G.; Dolique, V.; Donovan, F.; Dooley, K. L.; Doravari, S.; Douglas, R.; Downes, T. P.; Drago, M.; Drever, R. W. P.; Driggers, J. C.; Du, Z.; Ducrot, M.; Dwyer, S. E.; Edo, T. B.; Edwards, M. C.; Effler, A.; Eggenstein, H.-B.; Ehrens, P.; Eichholz, J.; Eikenberry, S. S.; Engels, W.; Essick, R. C.; Etzel, T.; Evans, M.; Evans, T. M.; Everett, R.; Factourovich, M.; Fafone, V.; Fair, H.; Fairhurst, S.; Fan, X.; Fang, Q.; Farinon, S.; Farr, B.; Farr, W. M.; Favata, M.; Fays, M.; Fehrmann, H.; Fejer, M. M.; Ferrante, I.; Ferreira, E. C.; Ferrini, F.; Fidecaro, F.; Fiori, I.; Fiorucci, D.; Fisher, R. P.; Flaminio, R.; Fletcher, M.; Fournier, J.-D.; Franco, S.; Frasca, S.; Frasconi, F.; Frei, Z.; Freise, A.; Frey, R.; Frey, V.; Fricke, T. T.; Fritschel, P.; Frolov, V. V.; Fulda, P.; Fyffe, M.; Gabbard, H. A. G.; Gair, J. R.; Gammaitoni, L.; Gaonkar, S. G.; Garufi, F.; Gatto, A.; Gaur, G.; Gehrels, N.; Gemme, G.; Gendre, B.; Genin, E.; Gennai, A.; George, J.; Gergely, L.; Germain, V.; Ghosh, Abhirup; Ghosh, Archisman; Ghosh, S.; Giaime, J. A.; Giardina, K. D.; Giazotto, A.; Gill, K.; Glaefke, A.; Goetz, E.; Goetz, R.; Gondan, L.; González, G.; Gonzalez Castro, J. M.; Gopakumar, A.; Gordon, N. A.; Gorodetsky, M. L.; Gossan, S. E.; Gosselin, M.; Gouaty, R.; Graef, C.; Graff, P. B.; Granata, M.; Grant, A.; Gras, S.; Gray, C.; Greco, G.; Green, A. C.; Groot, P.; Grote, H.; Grunewald, S.; Guidi, G. M.; Guo, X.; Gupta, A.; Gupta, M. K.; Gushwa, K. E.; Gustafson, E. K.; Gustafson, R.; Hacker, J. J.; Hall, B. R.; Hall, E. D.; Hammond, G.; Haney, M.; Hanke, M. M.; Hanks, J.; Hanna, C.; Hannam, M. D.; Hanson, J.; Hardwick, T.; Harms, J.; Harry, G. M.; Harry, I. W.; Hart, M. J.; Hartman, M. T.; Haster, C.-J.; Haughian, K.; Healy, J.; Heidmann, A.; Heintze, M. C.; Heitmann, H.; Hello, P.; Hemming, G.; Hendry, M.; Heng, I. S.; Hennig, J.; Heptonstall, A. W.; Heurs, M.; Hild, S.; Hoak, D.; Hodge, K. A.; Hofman, D.; Hollitt, S. E.; Holt, K.; Holz, D. E.; Hopkins, P.; Hosken, D. J.; Hough, J.; Houston, E. A.; Howell, E. J.; Hu, Y. M.; Huang, S.; Huerta, E. A.; Huet, D.; Hughey, B.; Husa, S.; Huttner, S. H.; Huynh-Dinh, T.; Idrisy, A.; Indik, N.; Ingram, D. R.; Inta, R.; Isa, H. N.; Isac, J.-M.; Isi, M.; Islas, G.; Isogai, T.; Iyer, B. R.; Izumi, K.; Jacqmin, T.; Jang, H.; Jani, K.; Jaranowski, P.; Jawahar, S.; Jiménez-Forteza, F.; Johnson, W. W.; Johnson-McDaniel, N. K.; Jones, D. I.; Jones, R.; Jonker, R. J. G.; Ju, L.; Haris, M. K.; Kalaghatgi, C. V.; Kalogera, V.; Kandhasamy, S.; Kang, G.; Kanner, J. B.; Karki, S.; Kasprzack, M.; Katsavounidis, E.; Katzman, W.; Kaufer, S.; Kaur, T.; Kawabe, K.; Kawazoe, F.; Kéfélian, F.; Kehl, M. S.; Keitel, D.; Kelley, D. B.; Kells, W.; Kennedy, R.; Key, J. S.; Khalaidovski, A.; Khalili, F. Y.; Khan, I.; Khan, S.; Khan, Z.; Khazanov, E. A.; Kijbunchoo, N.; Kim, C.; Kim, J.; Kim, K.; Kim, Nam-Gyu; Kim, Namjun; Kim, Y.-M.; King, E. J.; King, P. J.; Kinzel, D. L.; Kissel, J. S.; Kleybolte, L.; Klimenko, S.; Koehlenbeck, S. M.; Kokeyama, K.; Koley, S.; Kondrashov, V.; Kontos, A.; Korobko, M.; Korth, W. Z.; Kowalska, I.; Kozak, D. B.; Kringel, V.; Krishnan, B.; Królak, A.; Krueger, C.; Kuehn, G.; Kumar, P.; Kuo, L.; Kutynia, A.; Lackey, B. D.; Landry, M.; Lange, J.; Lantz, B.; Lasky, P. D.; Lazzarini, A.; Lazzaro, C.; Leaci, P.; Leavey, S.; Lebigot, E. O.; Lee, C. H.; Lee, H. K.; Lee, H. M.; Lee, K.; Lenon, A.; Leonardi, M.; Leong, J. R.; Leroy, N.; Letendre, N.; Levin, Y.; Levine, B. M.; Li, T. G. F.; Libson, A.; Littenberg, T. B.; Lockerbie, N. A.; Logue, J.; Lombardi, A. L.; London, L. T.; Lord, J. E.; Lorenzini, M.; Loriette, V.; Lormand, M.; Losurdo, G.; Lough, J. D.; Lousto, C. O.; Lovelace, G.; Lück, H.; Lundgren, A. P.; Luo, J.; Lynch, R.; Ma, Y.; MacDonald, T.; Machenschalk, B.; MacInnis, M.; Macleod, D. M.; Magaña-Sandoval, F.; Magee, R. M.; Mageswaran, M.; Majorana, E.; Maksimovic, I.; Malvezzi, V.; Man, N.; Mandel, I.; Mandic, V.; Mangano, V.; Mansell, G. L.; Manske, M.; Mantovani, M.; Marchesoni, F.; Marion, F.; Márka, S.; Márka, Z.; Markosyan, A. S.; Maros, E.; Martelli, F.; Martellini, L.; Martin, I. W.; Martin, R. M.; Martynov, D. V.; Marx, J. N.; Mason, K.; Masserot, A.; Massinger, T. J.; Masso-Reid, M.; Matichard, F.; Matone, L.; Mavalvala, N.; Mazumder, N.; Mazzolo, G.; McCarthy, R.; McClelland, D. E.; McCormick, S.; McGuire, S. C.; McIntyre, G.; McIver, J.; McManus, D. J.; McWilliams, S. T.; Meacher, D.; Meadors, G. D.; Meidam, J.; Melatos, A.; Mendell, G.; Mendoza-Gandara, D.; Mercer, R. A.; Merilh, E.; Merzougui, M.; Meshkov, S.; Messenger, C.; Messick, C.; Meyers, P. M.; Mezzani, F.; Miao, H.; Michel, C.; Middleton, H.; Mikhailov, E. E.; Milano, L.; Miller, J.; Millhouse, M.; Minenkov, Y.; Ming, J.; Mirshekari, S.; Mishra, C.; Mitra, S.; Mitrofanov, V. P.; Mitselmakher, G.; Mittleman, R.; Moggi, A.; Mohan, M.; Mohapatra, S. R. P.; Montani, M.; Moore, B. C.; Moore, C. J.; Moraru, D.; Moreno, G.; Morriss, S. R.; Mossavi, K.; Mours, B.; Mow-Lowry, C. M.; Mueller, C. L.; Mueller, G.; Muir, A. W.; Mukherjee, Arunava; Mukherjee, D.; Mukherjee, S.; Mukund, N.; Mullavey, A.; Munch, J.; Murphy, D. J.; Murray, P. G.; Mytidis, A.; Nardecchia, I.; Naticchioni, L.; Nayak, R. K.; Necula, V.; Nedkova, K.; Nelemans, G.; Neri, M.; Neunzert, A.; Newton, G.; Nguyen, T. T.; Nielsen, A. B.; Nissanke, S.; Nitz, A.; Nocera, F.; Nolting, D.; Normandin, M. E.; Nuttall, L. K.; Oberling, J.; Ochsner, E.; O'Dell, J.; Oelker, E.; Ogin, G. H.; Oh, J. J.; Oh, S. H.; Ohme, F.; Oliver, M.; Oppermann, P.; Oram, Richard J.; O'Reilly, B.; O'Shaughnessy, R.; Ottaway, D. J.; Ottens, R. S.; Overmier, H.; Owen, B. J.; Pai, A.; Pai, S. A.; Palamos, J. R.; Palashov, O.; Palomba, C.; Pal-Singh, A.; Pan, H.; Pan, Y.; Pankow, C.; Pannarale, F.; Pant, B. C.; Paoletti, F.; Paoli, A.; Papa, M. A.; Paris, H. R.; Parker, W.; Pascucci, D.; Pasqualetti, A.; Passaquieti, R.; Passuello, D.; Patricelli, B.; Patrick, Z.; Pearlstone, B. L.; Pedraza, M.; Pedurand, R.; Pekowsky, L.; Pele, A.; Penn, S.; Perreca, A.; Pfeiffer, H. P.; Phelps, M.; Piccinni, O.; Pichot, M.; Piergiovanni, F.; Pierro, V.; Pillant, G.; Pinard, L.; Pinto, I. M.; Pitkin, M.; Poggiani, R.; Popolizio, P.; Post, A.; Powell, J.; Prasad, J.; Predoi, V.; Premachandra, S. S.; Prestegard, T.; Price, L. R.; Prijatelj, M.; Principe, M.; Privitera, S.; Prix, R.; Prodi, G. A.; Prokhorov, L.; Puncken, O.; Punturo, M.; Puppo, P.; Pürrer, M.; Qi, H.; Qin, J.; Quetschke, V.; Quintero, E. A.; Quitzow-James, R.; Raab, F. J.; Rabeling, D. S.; Radkins, H.; Raffai, P.; Raja, S.; Rakhmanov, M.; Rapagnani, P.; Raymond, V.; Razzano, M.; Re, V.; Read, J.; Reed, C. M.; Regimbau, T.; Rei, L.; Reid, S.; Reitze, D. H.; Rew, H.; Reyes, S. D.; Ricci, F.; Riles, K.; Robertson, N. A.; Robie, R.; Robinet, F.; Rocchi, A.; Rolland, L.; Rollins, J. G.; Roma, V. J.; Romano, R.; Romanov, G.; Romie, J. H.; Rosińska, D.; Rowan, S.; Rüdiger, A.; Ruggi, P.; Ryan, K.; Sachdev, S.; Sadecki, T.; Sadeghian, L.; Salconi, L.; Saleem, M.; Salemi, F.; Samajdar, A.; Sammut, L.; Sanchez, E. J.; Sandberg, V.; Sandeen, B.; Sanders, J. R.; Sassolas, B.; Sathyaprakash, B. S.; Saulson, P. R.; Sauter, O.; Savage, R. L.; Sawadsky, A.; Schale, P.; Schilling, R.; Schmidt, J.; Schmidt, P.; Schnabel, R.; Schofield, R. M. S.; Schönbeck, A.; Schreiber, E.; Schuette, D.; Schutz, B. F.; Scott, J.; Scott, S. M.; Sellers, D.; Sengupta, A. S.; Sentenac, D.; Sequino, V.; Sergeev, A.; Serna, G.; Setyawati, Y.; Sevigny, A.; Shaddock, D. A.; Shah, S.; Shahriar, M. S.; Shaltev, M.; Shao, Z.; Shapiro, B.; Shawhan, P.; Sheperd, A.; Shoemaker, D. H.; Shoemaker, D. M.; Siellez, K.; Siemens, X.; Sigg, D.; Silva, A. D.; Simakov, D.; Singer, A.; Singer, L. P.; Singh, A.; Singh, R.; Singhal, A.; Sintes, A. M.; Slagmolen, B. J. J.; Smith, J. R.; Smith, N. D.; Smith, R. J. E.; Son, E. J.; Sorazu, B.; Sorrentino, F.; Souradeep, T.; Srivastava, A. K.; Staley, A.; Steinke, M.; Steinlechner, J.; Steinlechner, S.; Steinmeyer, D.; Stephens, B. C.; Stone, R.; Strain, K. A.; Straniero, N.; Stratta, G.; Strauss, N. A.; Strigin, S.; Sturani, R.; Stuver, A. L.; Summerscales, T. Z.; Sun, L.; Sutton, P. J.; Swinkels, B. L.; Szczepańczyk, M. J.; Tacca, M.; Talukder, D.; Tanner, D. B.; Tápai, M.; Tarabrin, S. P.; Taracchini, A.; Taylor, R.; Theeg, T.; Thirugnanasambandam, M. P.; Thomas, E. G.; Thomas, M.; Thomas, P.; Thorne, K. A.; Thorne, K. S.; Thrane, E.; Tiwari, S.; Tiwari, V.; Tokmakov, K. V.; Tomlinson, C.; Tonelli, M.; Torres, C. V.; Torrie, C. I.; Töyrä, D.; Travasso, F.; Traylor, G.; Trifirò, D.; Tringali, M. C.; Trozzo, L.; Tse, M.; Turconi, M.; Tuyenbayev, D.; Ugolini, D.; Unnikrishnan, C. S.; Urban, A. L.; Usman, S. A.; Vahlbruch, H.; Vajente, G.; Valdes, G.; Vallisneri, M.; van Bakel, N.; van Beuzekom, M.; van den Brand, J. F. J.; Van Den Broeck, C.; Vander-Hyde, D. C.; van der Schaaf, L.; van Heijningen, J. V.; van Veggel, A. A.; Vardaro, M.; Vass, S.; Vasúth, M.; Vaulin, R.; Vecchio, A.; Vedovato, G.; Veitch, J.; Veitch, P. J.; Venkateswara, K.; Verkindt, D.; Vetrano, F.; Viceré, A.; Vinciguerra, S.; Vine, D. J.; Vinet, J.-Y.; Vitale, S.; Vo, T.; Vocca, H.; Vorvick, C.; Voss, D.; Vousden, W. D.; Vyatchanin, S. P.; Wade, A. R.; Wade, L. E.; Wade, M.; Walker, M.; Wallace, L.; Walsh, S.; Wang, G.; Wang, H.; Wang, M.; Wang, X.; Wang, Y.; Ward, R. L.; Warner, J.; Was, M.; Weaver, B.; Wei, L.-W.; Weinert, M.; Weinstein, A. J.; Weiss, R.; Welborn, T.; Wen, L.; Weßels, P.; Westphal, T.; Wette, K.; Whelan, J. T.; White, D. J.; Whiting, B. F.; Williams, D.; Williams, R. D.; Williamson, A. R.; Willis, J. L.; Willke, B.; Wimmer, M. H.; Winkler, W.; Wipf, C. C.; Wittel, H.; Woan, G.; Worden, J.; Wright, J. L.; Wu, G.; Yablon, J.; Yam, W.; Yamamoto, H.; Yancey, C. C.; Yap, M. J.; Yu, H.; Yvert, M.; ZadroŻny, A.; Zangrando, L.; Zanolin, M.; Zendri, J.-P.; Zevin, M.; Zhang, F.; Zhang, L.; Zhang, M.; Zhang, Y.; Zhao, C.; Zhou, M.; Zhou, Z.; Zhu, X. J.; Zucker, M. E.; Zuraw, S. E.; Zweizig, J.; Boyle, M.; Campanelli, M.; Hemberger, D. A.; Kidder, L. E.; Ossokine, S.; Scheel, M. A.; Szilagyi, B.; Teukolsky, S.; Zlochower, Y.; LIGO Scientific; Virgo Collaborations

    2016-06-01

    The LIGO detection of GW150914 provides an unprecedented opportunity to study the two-body motion of a compact-object binary in the large-velocity, highly nonlinear regime, and to witness the final merger of the binary and the excitation of uniquely relativistic modes of the gravitational field. We carry out several investigations to determine whether GW150914 is consistent with a binary black-hole merger in general relativity. We find that the final remnant's mass and spin, as determined from the low-frequency (inspiral) and high-frequency (postinspiral) phases of the signal, are mutually consistent with the binary black-hole solution in general relativity. Furthermore, the data following the peak of GW150914 are consistent with the least-damped quasinormal mode inferred from the mass and spin of the remnant black hole. By using waveform models that allow for parametrized general-relativity violations during the inspiral and merger phases, we perform quantitative tests on the gravitational-wave phase in the dynamical regime and we determine the first empirical bounds on several high-order post-Newtonian coefficients. We constrain the graviton Compton wavelength, assuming that gravitons are dispersed in vacuum in the same way as particles with mass, obtaining a 90%-confidence lower bound of 1013 km . In conclusion, within our statistical uncertainties, we find no evidence for violations of general relativity in the genuinely strong-field regime of gravity.

  20. Tests of General Relativity with GW150914.

    PubMed

    Abbott, B P; Abbott, R; Abbott, T D; Abernathy, M R; Acernese, F; Ackley, K; Adams, C; Adams, T; Addesso, P; Adhikari, R X; Adya, V B; Affeldt, C; Agathos, M; Agatsuma, K; Aggarwal, N; Aguiar, O D; Aiello, L; Ain, A; Ajith, P; Allen, B; Allocca, A; Altin, P A; Anderson, S B; Anderson, W G; Arai, K; Araya, M C; Arceneaux, C C; Areeda, J S; Arnaud, N; Arun, K G; Ascenzi, S; Ashton, G; Ast, M; Aston, S M; Astone, P; Aufmuth, P; Aulbert, C; Babak, S; Bacon, P; Bader, M K M; Baker, P T; Baldaccini, F; Ballardin, G; Ballmer, S W; Barayoga, J C; Barclay, S E; Barish, B C; Barker, D; Barone, F; Barr, B; Barsotti, L; Barsuglia, M; Barta, D; Bartlett, J; Bartos, I; Bassiri, R; Basti, A; Batch, J C; Baune, C; Bavigadda, V; Bazzan, M; Behnke, B; Bejger, M; Bell, A S; Bell, C J; Berger, B K; Bergman, J; Bergmann, G; Berry, C P L; Bersanetti, D; Bertolini, A; Betzwieser, J; Bhagwat, S; Bhandare, R; Bilenko, I A; Billingsley, G; Birch, J; Birney, R; Birnholtz, O; Biscans, S; Bisht, A; Bitossi, M; Biwer, C; Bizouard, M A; Blackburn, J K; Blair, C D; Blair, D G; Blair, R M; Bloemen, S; Bock, O; Bodiya, T P; Boer, M; Bogaert, G; Bogan, C; Bohe, A; Bojtos, P; Bond, C; Bondu, F; Bonnand, R; Boom, B A; Bork, R; Boschi, V; Bose, S; Bouffanais, Y; Bozzi, A; Bradaschia, C; Brady, P R; Braginsky, V B; Branchesi, M; Brau, J E; Briant, T; Brillet, A; Brinkmann, M; Brisson, V; Brockill, P; Brooks, A F; Brown, D A; Brown, D D; Brown, N M; Buchanan, C C; Buikema, A; Bulik, T; Bulten, H J; Buonanno, A; Buskulic, D; Buy, C; Byer, R L; Cadonati, L; Cagnoli, G; Cahillane, C; Calderón Bustillo, J; Callister, T; Calloni, E; Camp, J B; Cannon, K C; Cao, J; Capano, C D; Capocasa, E; Carbognani, F; Caride, S; Casanueva Diaz, J; Casentini, C; Caudill, S; Cavaglià, M; Cavalier, F; Cavalieri, R; Cella, G; Cepeda, C B; Cerboni Baiardi, L; Cerretani, G; Cesarini, E; Chakraborty, R; Chalermsongsak, T; Chamberlin, S J; Chan, M; Chao, S; Charlton, P; Chassande-Mottin, E; Chen, H Y; Chen, Y; Cheng, C; Chincarini, A; Chiummo, A; Cho, H S; Cho, M; Chow, J H; Christensen, N; Chu, Q; Chua, S; Chung, S; Ciani, G; Clara, F; Clark, J A; Cleva, F; Coccia, E; Cohadon, P-F; Colla, A; Collette, C G; Cominsky, L; Constancio, M; Conte, A; Conti, L; Cook, D; Corbitt, T R; Cornish, N; Corsi, A; Cortese, S; Costa, C A; Coughlin, M W; Coughlin, S B; Coulon, J-P; Countryman, S T; Couvares, P; Cowan, E E; Coward, D M; Cowart, M J; Coyne, D C; Coyne, R; Craig, K; Creighton, J D E; Cripe, J; Crowder, S G; Cumming, A; Cunningham, L; Cuoco, E; Dal Canton, T; Danilishin, S L; D'Antonio, S; Danzmann, K; Darman, N S; Dattilo, V; Dave, I; Daveloza, H P; Davier, M; Davies, G S; Daw, E J; Day, R; DeBra, D; Debreczeni, G; Degallaix, J; De Laurentis, M; Deléglise, S; Del Pozzo, W; Denker, T; Dent, T; Dereli, H; Dergachev, V; De Rosa, R; DeRosa, R T; DeSalvo, R; Dhurandhar, S; Díaz, M C; Di Fiore, L; Di Giovanni, M; Di Lieto, A; Di Pace, S; Di Palma, I; Di Virgilio, A; Dojcinoski, G; Dolique, V; Donovan, F; Dooley, K L; Doravari, S; Douglas, R; Downes, T P; Drago, M; Drever, R W P; Driggers, J C; Du, Z; Ducrot, M; Dwyer, S E; Edo, T B; Edwards, M C; Effler, A; Eggenstein, H-B; Ehrens, P; Eichholz, J; Eikenberry, S S; Engels, W; Essick, R C; Etzel, T; Evans, M; Evans, T M; Everett, R; Factourovich, M; Fafone, V; Fair, H; Fairhurst, S; Fan, X; Fang, Q; Farinon, S; Farr, B; Farr, W M; Favata, M; Fays, M; Fehrmann, H; Fejer, M M; Ferrante, I; Ferreira, E C; Ferrini, F; Fidecaro, F; Fiori, I; Fiorucci, D; Fisher, R P; Flaminio, R; Fletcher, M; Fournier, J-D; Franco, S; Frasca, S; Frasconi, F; Frei, Z; Freise, A; Frey, R; Frey, V; Fricke, T T; Fritschel, P; Frolov, V V; Fulda, P; Fyffe, M; Gabbard, H A G; Gair, J R; Gammaitoni, L; Gaonkar, S G; Garufi, F; Gatto, A; Gaur, G; Gehrels, N; Gemme, G; Gendre, B; Genin, E; Gennai, A; George, J; Gergely, L; Germain, V; Ghosh, Abhirup; Ghosh, Archisman; Ghosh, S; Giaime, J A; Giardina, K D; Giazotto, A; Gill, K; Glaefke, A; Goetz, E; Goetz, R; Gondan, L; González, G; Gonzalez Castro, J M; Gopakumar, A; Gordon, N A; Gorodetsky, M L; Gossan, S E; Gosselin, M; Gouaty, R; Graef, C; Graff, P B; Granata, M; Grant, A; Gras, S; Gray, C; Greco, G; Green, A C; Groot, P; Grote, H; Grunewald, S; Guidi, G M; Guo, X; Gupta, A; Gupta, M K; Gushwa, K E; Gustafson, E K; Gustafson, R; Hacker, J J; Hall, B R; Hall, E D; Hammond, G; Haney, M; Hanke, M M; Hanks, J; Hanna, C; Hannam, M D; Hanson, J; Hardwick, T; Harms, J; Harry, G M; Harry, I W; Hart, M J; Hartman, M T; Haster, C-J; Haughian, K; Healy, J; Heidmann, A; Heintze, M C; Heitmann, H; Hello, P; Hemming, G; Hendry, M; Heng, I S; Hennig, J; Heptonstall, A W; Heurs, M; Hild, S; Hoak, D; Hodge, K A; Hofman, D; Hollitt, S E; Holt, K; Holz, D E; Hopkins, P; Hosken, D J; Hough, J; Houston, E A; Howell, E J; Hu, Y M; Huang, S; Huerta, E A; Huet, D; Hughey, B; Husa, S; Huttner, S H; Huynh-Dinh, T; Idrisy, A; Indik, N; Ingram, D R; Inta, R; Isa, H N; Isac, J-M; Isi, M; Islas, G; Isogai, T; Iyer, B R; Izumi, K; Jacqmin, T; Jang, H; Jani, K; Jaranowski, P; Jawahar, S; Jiménez-Forteza, F; Johnson, W W; Johnson-McDaniel, N K; Jones, D I; Jones, R; Jonker, R J G; Ju, L; Haris, M K; Kalaghatgi, C V; Kalogera, V; Kandhasamy, S; Kang, G; Kanner, J B; Karki, S; Kasprzack, M; Katsavounidis, E; Katzman, W; Kaufer, S; Kaur, T; Kawabe, K; Kawazoe, F; Kéfélian, F; Kehl, M S; Keitel, D; Kelley, D B; Kells, W; Kennedy, R; Key, J S; Khalaidovski, A; Khalili, F Y; Khan, I; Khan, S; Khan, Z; Khazanov, E A; Kijbunchoo, N; Kim, C; Kim, J; Kim, K; Kim, Nam-Gyu; Kim, Namjun; Kim, Y-M; King, E J; King, P J; Kinzel, D L; Kissel, J S; Kleybolte, L; Klimenko, S; Koehlenbeck, S M; Kokeyama, K; Koley, S; Kondrashov, V; Kontos, A; Korobko, M; Korth, W Z; Kowalska, I; Kozak, D B; Kringel, V; Krishnan, B; Królak, A; Krueger, C; Kuehn, G; Kumar, P; Kuo, L; Kutynia, A; Lackey, B D; Landry, M; Lange, J; Lantz, B; Lasky, P D; Lazzarini, A; Lazzaro, C; Leaci, P; Leavey, S; Lebigot, E O; Lee, C H; Lee, H K; Lee, H M; Lee, K; Lenon, A; Leonardi, M; Leong, J R; Leroy, N; Letendre, N; Levin, Y; Levine, B M; Li, T G F; Libson, A; Littenberg, T B; Lockerbie, N A; Logue, J; Lombardi, A L; London, L T; Lord, J E; Lorenzini, M; Loriette, V; Lormand, M; Losurdo, G; Lough, J D; Lousto, C O; Lovelace, G; Lück, H; Lundgren, A P; Luo, J; Lynch, R; Ma, Y; MacDonald, T; Machenschalk, B; MacInnis, M; Macleod, D M; Magaña-Sandoval, F; Magee, R M; Mageswaran, M; Majorana, E; Maksimovic, I; Malvezzi, V; Man, N; Mandel, I; Mandic, V; Mangano, V; Mansell, G L; Manske, M; Mantovani, M; Marchesoni, F; Marion, F; Márka, S; Márka, Z; Markosyan, A S; Maros, E; Martelli, F; Martellini, L; Martin, I W; Martin, R M; Martynov, D V; Marx, J N; Mason, K; Masserot, A; Massinger, T J; Masso-Reid, M; Matichard, F; Matone, L; Mavalvala, N; Mazumder, N; Mazzolo, G; McCarthy, R; McClelland, D E; McCormick, S; McGuire, S C; McIntyre, G; McIver, J; McManus, D J; McWilliams, S T; Meacher, D; Meadors, G D; Meidam, J; Melatos, A; Mendell, G; Mendoza-Gandara, D; Mercer, R A; Merilh, E; Merzougui, M; Meshkov, S; Messenger, C; Messick, C; Meyers, P M; Mezzani, F; Miao, H; Michel, C; Middleton, H; Mikhailov, E E; Milano, L; Miller, J; Millhouse, M; Minenkov, Y; Ming, J; Mirshekari, S; Mishra, C; Mitra, S; Mitrofanov, V P; Mitselmakher, G; Mittleman, R; Moggi, A; Mohan, M; Mohapatra, S R P; Montani, M; Moore, B C; Moore, C J; Moraru, D; Moreno, G; Morriss, S R; Mossavi, K; Mours, B; Mow-Lowry, C M; Mueller, C L; Mueller, G; Muir, A W; Mukherjee, Arunava; Mukherjee, D; Mukherjee, S; Mukund, N; Mullavey, A; Munch, J; Murphy, D J; Murray, P G; Mytidis, A; Nardecchia, I; Naticchioni, L; Nayak, R K; Necula, V; Nedkova, K; Nelemans, G; Neri, M; Neunzert, A; Newton, G; Nguyen, T T; Nielsen, A B; Nissanke, S; Nitz, A; Nocera, F; Nolting, D; Normandin, M E; Nuttall, L K; Oberling, J; Ochsner, E; O'Dell, J; Oelker, E; Ogin, G H; Oh, J J; Oh, S H; Ohme, F; Oliver, M; Oppermann, P; Oram, Richard J; O'Reilly, B; O'Shaughnessy, R; Ottaway, D J; Ottens, R S; Overmier, H; Owen, B J; Pai, A; Pai, S A; Palamos, J R; Palashov, O; Palomba, C; Pal-Singh, A; Pan, H; Pan, Y; Pankow, C; Pannarale, F; Pant, B C; Paoletti, F; Paoli, A; Papa, M A; Paris, H R; Parker, W; Pascucci, D; Pasqualetti, A; Passaquieti, R; Passuello, D; Patricelli, B; Patrick, Z; Pearlstone, B L; Pedraza, M; Pedurand, R; Pekowsky, L; Pele, A; Penn, S; Perreca, A; Pfeiffer, H P; Phelps, M; Piccinni, O; Pichot, M; Piergiovanni, F; Pierro, V; Pillant, G; Pinard, L; Pinto, I M; Pitkin, M; Poggiani, R; Popolizio, P; Post, A; Powell, J; Prasad, J; Predoi, V; Premachandra, S S; Prestegard, T; Price, L R; Prijatelj, M; Principe, M; Privitera, S; Prix, R; Prodi, G A; Prokhorov, L; Puncken, O; Punturo, M; Puppo, P; Pürrer, M; Qi, H; Qin, J; Quetschke, V; Quintero, E A; Quitzow-James, R; Raab, F J; Rabeling, D S; Radkins, H; Raffai, P; Raja, S; Rakhmanov, M; Rapagnani, P; Raymond, V; Razzano, M; Re, V; Read, J; Reed, C M; Regimbau, T; Rei, L; Reid, S; Reitze, D H; Rew, H; Reyes, S D; Ricci, F; Riles, K; Robertson, N A; Robie, R; Robinet, F; Rocchi, A; Rolland, L; Rollins, J G; Roma, V J; Romano, R; Romanov, G; Romie, J H; Rosińska, D; Rowan, S; Rüdiger, A; Ruggi, P; Ryan, K; Sachdev, S; Sadecki, T; Sadeghian, L; Salconi, L; Saleem, M; Salemi, F; Samajdar, A; Sammut, L; Sanchez, E J; Sandberg, V; Sandeen, B; Sanders, J R; Sassolas, B; Sathyaprakash, B S; Saulson, P R; Sauter, O; Savage, R L; Sawadsky, A; Schale, P; Schilling, R; Schmidt, J; Schmidt, P; Schnabel, R; Schofield, R M S; Schönbeck, A; Schreiber, E; Schuette, D; Schutz, B F; Scott, J; Scott, S M; Sellers, D; Sengupta, A S; Sentenac, D; Sequino, V; Sergeev, A; Serna, G; Setyawati, Y; Sevigny, A; Shaddock, D A; Shah, S; Shahriar, M S; Shaltev, M; Shao, Z; Shapiro, B; Shawhan, P; Sheperd, A; Shoemaker, D H; Shoemaker, D M; Siellez, K; Siemens, X; Sigg, D; Silva, A D; Simakov, D; Singer, A; Singer, L P; Singh, A; Singh, R; Singhal, A; Sintes, A M; Slagmolen, B J J; Smith, J R; Smith, N D; Smith, R J E; Son, E J; Sorazu, B; Sorrentino, F; Souradeep, T; Srivastava, A K; Staley, A; Steinke, M; Steinlechner, J; Steinlechner, S; Steinmeyer, D; Stephens, B C; Stone, R; Strain, K A; Straniero, N; Stratta, G; Strauss, N A; Strigin, S; Sturani, R; Stuver, A L; Summerscales, T Z; Sun, L; Sutton, P J; Swinkels, B L; Szczepańczyk, M J; Tacca, M; Talukder, D; Tanner, D B; Tápai, M; Tarabrin, S P; Taracchini, A; Taylor, R; Theeg, T; Thirugnanasambandam, M P; Thomas, E G; Thomas, M; Thomas, P; Thorne, K A; Thorne, K S; Thrane, E; Tiwari, S; Tiwari, V; Tokmakov, K V; Tomlinson, C; Tonelli, M; Torres, C V; Torrie, C I; Töyrä, D; Travasso, F; Traylor, G; Trifirò, D; Tringali, M C; Trozzo, L; Tse, M; Turconi, M; Tuyenbayev, D; Ugolini, D; Unnikrishnan, C S; Urban, A L; Usman, S A; Vahlbruch, H; Vajente, G; Valdes, G; Vallisneri, M; van Bakel, N; van Beuzekom, M; van den Brand, J F J; Van Den Broeck, C; Vander-Hyde, D C; van der Schaaf, L; van Heijningen, J V; van Veggel, A A; Vardaro, M; Vass, S; Vasúth, M; Vaulin, R; Vecchio, A; Vedovato, G; Veitch, J; Veitch, P J; Venkateswara, K; Verkindt, D; Vetrano, F; Viceré, A; Vinciguerra, S; Vine, D J; Vinet, J-Y; Vitale, S; Vo, T; Vocca, H; Vorvick, C; Voss, D; Vousden, W D; Vyatchanin, S P; Wade, A R; Wade, L E; Wade, M; Walker, M; Wallace, L; Walsh, S; Wang, G; Wang, H; Wang, M; Wang, X; Wang, Y; Ward, R L; Warner, J; Was, M; Weaver, B; Wei, L-W; Weinert, M; Weinstein, A J; Weiss, R; Welborn, T; Wen, L; Weßels, P; Westphal, T; Wette, K; Whelan, J T; White, D J; Whiting, B F; Williams, D; Williams, R D; Williamson, A R; Willis, J L; Willke, B; Wimmer, M H; Winkler, W; Wipf, C C; Wittel, H; Woan, G; Worden, J; Wright, J L; Wu, G; Yablon, J; Yam, W; Yamamoto, H; Yancey, C C; Yap, M J; Yu, H; Yvert, M; Zadrożny, A; Zangrando, L; Zanolin, M; Zendri, J-P; Zevin, M; Zhang, F; Zhang, L; Zhang, M; Zhang, Y; Zhao, C; Zhou, M; Zhou, Z; Zhu, X J; Zucker, M E; Zuraw, S E; Zweizig, J; Boyle, M; Campanelli, M; Hemberger, D A; Kidder, L E; Ossokine, S; Scheel, M A; Szilagyi, B; Teukolsky, S; Zlochower, Y

    2016-06-01

    The LIGO detection of GW150914 provides an unprecedented opportunity to study the two-body motion of a compact-object binary in the large-velocity, highly nonlinear regime, and to witness the final merger of the binary and the excitation of uniquely relativistic modes of the gravitational field. We carry out several investigations to determine whether GW150914 is consistent with a binary black-hole merger in general relativity. We find that the final remnant's mass and spin, as determined from the low-frequency (inspiral) and high-frequency (postinspiral) phases of the signal, are mutually consistent with the binary black-hole solution in general relativity. Furthermore, the data following the peak of GW150914 are consistent with the least-damped quasinormal mode inferred from the mass and spin of the remnant black hole. By using waveform models that allow for parametrized general-relativity violations during the inspiral and merger phases, we perform quantitative tests on the gravitational-wave phase in the dynamical regime and we determine the first empirical bounds on several high-order post-Newtonian coefficients. We constrain the graviton Compton wavelength, assuming that gravitons are dispersed in vacuum in the same way as particles with mass, obtaining a 90%-confidence lower bound of 10^{13}  km. In conclusion, within our statistical uncertainties, we find no evidence for violations of general relativity in the genuinely strong-field regime of gravity.

  1. Tests of General Relativity with GW150914.

    PubMed

    Abbott, B P; Abbott, R; Abbott, T D; Abernathy, M R; Acernese, F; Ackley, K; Adams, C; Adams, T; Addesso, P; Adhikari, R X; Adya, V B; Affeldt, C; Agathos, M; Agatsuma, K; Aggarwal, N; Aguiar, O D; Aiello, L; Ain, A; Ajith, P; Allen, B; Allocca, A; Altin, P A; Anderson, S B; Anderson, W G; Arai, K; Araya, M C; Arceneaux, C C; Areeda, J S; Arnaud, N; Arun, K G; Ascenzi, S; Ashton, G; Ast, M; Aston, S M; Astone, P; Aufmuth, P; Aulbert, C; Babak, S; Bacon, P; Bader, M K M; Baker, P T; Baldaccini, F; Ballardin, G; Ballmer, S W; Barayoga, J C; Barclay, S E; Barish, B C; Barker, D; Barone, F; Barr, B; Barsotti, L; Barsuglia, M; Barta, D; Bartlett, J; Bartos, I; Bassiri, R; Basti, A; Batch, J C; Baune, C; Bavigadda, V; Bazzan, M; Behnke, B; Bejger, M; Bell, A S; Bell, C J; Berger, B K; Bergman, J; Bergmann, G; Berry, C P L; Bersanetti, D; Bertolini, A; Betzwieser, J; Bhagwat, S; Bhandare, R; Bilenko, I A; Billingsley, G; Birch, J; Birney, R; Birnholtz, O; Biscans, S; Bisht, A; Bitossi, M; Biwer, C; Bizouard, M A; Blackburn, J K; Blair, C D; Blair, D G; Blair, R M; Bloemen, S; Bock, O; Bodiya, T P; Boer, M; Bogaert, G; Bogan, C; Bohe, A; Bojtos, P; Bond, C; Bondu, F; Bonnand, R; Boom, B A; Bork, R; Boschi, V; Bose, S; Bouffanais, Y; Bozzi, A; Bradaschia, C; Brady, P R; Braginsky, V B; Branchesi, M; Brau, J E; Briant, T; Brillet, A; Brinkmann, M; Brisson, V; Brockill, P; Brooks, A F; Brown, D A; Brown, D D; Brown, N M; Buchanan, C C; Buikema, A; Bulik, T; Bulten, H J; Buonanno, A; Buskulic, D; Buy, C; Byer, R L; Cadonati, L; Cagnoli, G; Cahillane, C; Calderón Bustillo, J; Callister, T; Calloni, E; Camp, J B; Cannon, K C; Cao, J; Capano, C D; Capocasa, E; Carbognani, F; Caride, S; Casanueva Diaz, J; Casentini, C; Caudill, S; Cavaglià, M; Cavalier, F; Cavalieri, R; Cella, G; Cepeda, C B; Cerboni Baiardi, L; Cerretani, G; Cesarini, E; Chakraborty, R; Chalermsongsak, T; Chamberlin, S J; Chan, M; Chao, S; Charlton, P; Chassande-Mottin, E; Chen, H Y; Chen, Y; Cheng, C; Chincarini, A; Chiummo, A; Cho, H S; Cho, M; Chow, J H; Christensen, N; Chu, Q; Chua, S; Chung, S; Ciani, G; Clara, F; Clark, J A; Cleva, F; Coccia, E; Cohadon, P-F; Colla, A; Collette, C G; Cominsky, L; Constancio, M; Conte, A; Conti, L; Cook, D; Corbitt, T R; Cornish, N; Corsi, A; Cortese, S; Costa, C A; Coughlin, M W; Coughlin, S B; Coulon, J-P; Countryman, S T; Couvares, P; Cowan, E E; Coward, D M; Cowart, M J; Coyne, D C; Coyne, R; Craig, K; Creighton, J D E; Cripe, J; Crowder, S G; Cumming, A; Cunningham, L; Cuoco, E; Dal Canton, T; Danilishin, S L; D'Antonio, S; Danzmann, K; Darman, N S; Dattilo, V; Dave, I; Daveloza, H P; Davier, M; Davies, G S; Daw, E J; Day, R; DeBra, D; Debreczeni, G; Degallaix, J; De Laurentis, M; Deléglise, S; Del Pozzo, W; Denker, T; Dent, T; Dereli, H; Dergachev, V; De Rosa, R; DeRosa, R T; DeSalvo, R; Dhurandhar, S; Díaz, M C; Di Fiore, L; Di Giovanni, M; Di Lieto, A; Di Pace, S; Di Palma, I; Di Virgilio, A; Dojcinoski, G; Dolique, V; Donovan, F; Dooley, K L; Doravari, S; Douglas, R; Downes, T P; Drago, M; Drever, R W P; Driggers, J C; Du, Z; Ducrot, M; Dwyer, S E; Edo, T B; Edwards, M C; Effler, A; Eggenstein, H-B; Ehrens, P; Eichholz, J; Eikenberry, S S; Engels, W; Essick, R C; Etzel, T; Evans, M; Evans, T M; Everett, R; Factourovich, M; Fafone, V; Fair, H; Fairhurst, S; Fan, X; Fang, Q; Farinon, S; Farr, B; Farr, W M; Favata, M; Fays, M; Fehrmann, H; Fejer, M M; Ferrante, I; Ferreira, E C; Ferrini, F; Fidecaro, F; Fiori, I; Fiorucci, D; Fisher, R P; Flaminio, R; Fletcher, M; Fournier, J-D; Franco, S; Frasca, S; Frasconi, F; Frei, Z; Freise, A; Frey, R; Frey, V; Fricke, T T; Fritschel, P; Frolov, V V; Fulda, P; Fyffe, M; Gabbard, H A G; Gair, J R; Gammaitoni, L; Gaonkar, S G; Garufi, F; Gatto, A; Gaur, G; Gehrels, N; Gemme, G; Gendre, B; Genin, E; Gennai, A; George, J; Gergely, L; Germain, V; Ghosh, Abhirup; Ghosh, Archisman; Ghosh, S; Giaime, J A; Giardina, K D; Giazotto, A; Gill, K; Glaefke, A; Goetz, E; Goetz, R; Gondan, L; González, G; Gonzalez Castro, J M; Gopakumar, A; Gordon, N A; Gorodetsky, M L; Gossan, S E; Gosselin, M; Gouaty, R; Graef, C; Graff, P B; Granata, M; Grant, A; Gras, S; Gray, C; Greco, G; Green, A C; Groot, P; Grote, H; Grunewald, S; Guidi, G M; Guo, X; Gupta, A; Gupta, M K; Gushwa, K E; Gustafson, E K; Gustafson, R; Hacker, J J; Hall, B R; Hall, E D; Hammond, G; Haney, M; Hanke, M M; Hanks, J; Hanna, C; Hannam, M D; Hanson, J; Hardwick, T; Harms, J; Harry, G M; Harry, I W; Hart, M J; Hartman, M T; Haster, C-J; Haughian, K; Healy, J; Heidmann, A; Heintze, M C; Heitmann, H; Hello, P; Hemming, G; Hendry, M; Heng, I S; Hennig, J; Heptonstall, A W; Heurs, M; Hild, S; Hoak, D; Hodge, K A; Hofman, D; Hollitt, S E; Holt, K; Holz, D E; Hopkins, P; Hosken, D J; Hough, J; Houston, E A; Howell, E J; Hu, Y M; Huang, S; Huerta, E A; Huet, D; Hughey, B; Husa, S; Huttner, S H; Huynh-Dinh, T; Idrisy, A; Indik, N; Ingram, D R; Inta, R; Isa, H N; Isac, J-M; Isi, M; Islas, G; Isogai, T; Iyer, B R; Izumi, K; Jacqmin, T; Jang, H; Jani, K; Jaranowski, P; Jawahar, S; Jiménez-Forteza, F; Johnson, W W; Johnson-McDaniel, N K; Jones, D I; Jones, R; Jonker, R J G; Ju, L; Haris, M K; Kalaghatgi, C V; Kalogera, V; Kandhasamy, S; Kang, G; Kanner, J B; Karki, S; Kasprzack, M; Katsavounidis, E; Katzman, W; Kaufer, S; Kaur, T; Kawabe, K; Kawazoe, F; Kéfélian, F; Kehl, M S; Keitel, D; Kelley, D B; Kells, W; Kennedy, R; Key, J S; Khalaidovski, A; Khalili, F Y; Khan, I; Khan, S; Khan, Z; Khazanov, E A; Kijbunchoo, N; Kim, C; Kim, J; Kim, K; Kim, Nam-Gyu; Kim, Namjun; Kim, Y-M; King, E J; King, P J; Kinzel, D L; Kissel, J S; Kleybolte, L; Klimenko, S; Koehlenbeck, S M; Kokeyama, K; Koley, S; Kondrashov, V; Kontos, A; Korobko, M; Korth, W Z; Kowalska, I; Kozak, D B; Kringel, V; Krishnan, B; Królak, A; Krueger, C; Kuehn, G; Kumar, P; Kuo, L; Kutynia, A; Lackey, B D; Landry, M; Lange, J; Lantz, B; Lasky, P D; Lazzarini, A; Lazzaro, C; Leaci, P; Leavey, S; Lebigot, E O; Lee, C H; Lee, H K; Lee, H M; Lee, K; Lenon, A; Leonardi, M; Leong, J R; Leroy, N; Letendre, N; Levin, Y; Levine, B M; Li, T G F; Libson, A; Littenberg, T B; Lockerbie, N A; Logue, J; Lombardi, A L; London, L T; Lord, J E; Lorenzini, M; Loriette, V; Lormand, M; Losurdo, G; Lough, J D; Lousto, C O; Lovelace, G; Lück, H; Lundgren, A P; Luo, J; Lynch, R; Ma, Y; MacDonald, T; Machenschalk, B; MacInnis, M; Macleod, D M; Magaña-Sandoval, F; Magee, R M; Mageswaran, M; Majorana, E; Maksimovic, I; Malvezzi, V; Man, N; Mandel, I; Mandic, V; Mangano, V; Mansell, G L; Manske, M; Mantovani, M; Marchesoni, F; Marion, F; Márka, S; Márka, Z; Markosyan, A S; Maros, E; Martelli, F; Martellini, L; Martin, I W; Martin, R M; Martynov, D V; Marx, J N; Mason, K; Masserot, A; Massinger, T J; Masso-Reid, M; Matichard, F; Matone, L; Mavalvala, N; Mazumder, N; Mazzolo, G; McCarthy, R; McClelland, D E; McCormick, S; McGuire, S C; McIntyre, G; McIver, J; McManus, D J; McWilliams, S T; Meacher, D; Meadors, G D; Meidam, J; Melatos, A; Mendell, G; Mendoza-Gandara, D; Mercer, R A; Merilh, E; Merzougui, M; Meshkov, S; Messenger, C; Messick, C; Meyers, P M; Mezzani, F; Miao, H; Michel, C; Middleton, H; Mikhailov, E E; Milano, L; Miller, J; Millhouse, M; Minenkov, Y; Ming, J; Mirshekari, S; Mishra, C; Mitra, S; Mitrofanov, V P; Mitselmakher, G; Mittleman, R; Moggi, A; Mohan, M; Mohapatra, S R P; Montani, M; Moore, B C; Moore, C J; Moraru, D; Moreno, G; Morriss, S R; Mossavi, K; Mours, B; Mow-Lowry, C M; Mueller, C L; Mueller, G; Muir, A W; Mukherjee, Arunava; Mukherjee, D; Mukherjee, S; Mukund, N; Mullavey, A; Munch, J; Murphy, D J; Murray, P G; Mytidis, A; Nardecchia, I; Naticchioni, L; Nayak, R K; Necula, V; Nedkova, K; Nelemans, G; Neri, M; Neunzert, A; Newton, G; Nguyen, T T; Nielsen, A B; Nissanke, S; Nitz, A; Nocera, F; Nolting, D; Normandin, M E; Nuttall, L K; Oberling, J; Ochsner, E; O'Dell, J; Oelker, E; Ogin, G H; Oh, J J; Oh, S H; Ohme, F; Oliver, M; Oppermann, P; Oram, Richard J; O'Reilly, B; O'Shaughnessy, R; Ottaway, D J; Ottens, R S; Overmier, H; Owen, B J; Pai, A; Pai, S A; Palamos, J R; Palashov, O; Palomba, C; Pal-Singh, A; Pan, H; Pan, Y; Pankow, C; Pannarale, F; Pant, B C; Paoletti, F; Paoli, A; Papa, M A; Paris, H R; Parker, W; Pascucci, D; Pasqualetti, A; Passaquieti, R; Passuello, D; Patricelli, B; Patrick, Z; Pearlstone, B L; Pedraza, M; Pedurand, R; Pekowsky, L; Pele, A; Penn, S; Perreca, A; Pfeiffer, H P; Phelps, M; Piccinni, O; Pichot, M; Piergiovanni, F; Pierro, V; Pillant, G; Pinard, L; Pinto, I M; Pitkin, M; Poggiani, R; Popolizio, P; Post, A; Powell, J; Prasad, J; Predoi, V; Premachandra, S S; Prestegard, T; Price, L R; Prijatelj, M; Principe, M; Privitera, S; Prix, R; Prodi, G A; Prokhorov, L; Puncken, O; Punturo, M; Puppo, P; Pürrer, M; Qi, H; Qin, J; Quetschke, V; Quintero, E A; Quitzow-James, R; Raab, F J; Rabeling, D S; Radkins, H; Raffai, P; Raja, S; Rakhmanov, M; Rapagnani, P; Raymond, V; Razzano, M; Re, V; Read, J; Reed, C M; Regimbau, T; Rei, L; Reid, S; Reitze, D H; Rew, H; Reyes, S D; Ricci, F; Riles, K; Robertson, N A; Robie, R; Robinet, F; Rocchi, A; Rolland, L; Rollins, J G; Roma, V J; Romano, R; Romanov, G; Romie, J H; Rosińska, D; Rowan, S; Rüdiger, A; Ruggi, P; Ryan, K; Sachdev, S; Sadecki, T; Sadeghian, L; Salconi, L; Saleem, M; Salemi, F; Samajdar, A; Sammut, L; Sanchez, E J; Sandberg, V; Sandeen, B; Sanders, J R; Sassolas, B; Sathyaprakash, B S; Saulson, P R; Sauter, O; Savage, R L; Sawadsky, A; Schale, P; Schilling, R; Schmidt, J; Schmidt, P; Schnabel, R; Schofield, R M S; Schönbeck, A; Schreiber, E; Schuette, D; Schutz, B F; Scott, J; Scott, S M; Sellers, D; Sengupta, A S; Sentenac, D; Sequino, V; Sergeev, A; Serna, G; Setyawati, Y; Sevigny, A; Shaddock, D A; Shah, S; Shahriar, M S; Shaltev, M; Shao, Z; Shapiro, B; Shawhan, P; Sheperd, A; Shoemaker, D H; Shoemaker, D M; Siellez, K; Siemens, X; Sigg, D; Silva, A D; Simakov, D; Singer, A; Singer, L P; Singh, A; Singh, R; Singhal, A; Sintes, A M; Slagmolen, B J J; Smith, J R; Smith, N D; Smith, R J E; Son, E J; Sorazu, B; Sorrentino, F; Souradeep, T; Srivastava, A K; Staley, A; Steinke, M; Steinlechner, J; Steinlechner, S; Steinmeyer, D; Stephens, B C; Stone, R; Strain, K A; Straniero, N; Stratta, G; Strauss, N A; Strigin, S; Sturani, R; Stuver, A L; Summerscales, T Z; Sun, L; Sutton, P J; Swinkels, B L; Szczepańczyk, M J; Tacca, M; Talukder, D; Tanner, D B; Tápai, M; Tarabrin, S P; Taracchini, A; Taylor, R; Theeg, T; Thirugnanasambandam, M P; Thomas, E G; Thomas, M; Thomas, P; Thorne, K A; Thorne, K S; Thrane, E; Tiwari, S; Tiwari, V; Tokmakov, K V; Tomlinson, C; Tonelli, M; Torres, C V; Torrie, C I; Töyrä, D; Travasso, F; Traylor, G; Trifirò, D; Tringali, M C; Trozzo, L; Tse, M; Turconi, M; Tuyenbayev, D; Ugolini, D; Unnikrishnan, C S; Urban, A L; Usman, S A; Vahlbruch, H; Vajente, G; Valdes, G; Vallisneri, M; van Bakel, N; van Beuzekom, M; van den Brand, J F J; Van Den Broeck, C; Vander-Hyde, D C; van der Schaaf, L; van Heijningen, J V; van Veggel, A A; Vardaro, M; Vass, S; Vasúth, M; Vaulin, R; Vecchio, A; Vedovato, G; Veitch, J; Veitch, P J; Venkateswara, K; Verkindt, D; Vetrano, F; Viceré, A; Vinciguerra, S; Vine, D J; Vinet, J-Y; Vitale, S; Vo, T; Vocca, H; Vorvick, C; Voss, D; Vousden, W D; Vyatchanin, S P; Wade, A R; Wade, L E; Wade, M; Walker, M; Wallace, L; Walsh, S; Wang, G; Wang, H; Wang, M; Wang, X; Wang, Y; Ward, R L; Warner, J; Was, M; Weaver, B; Wei, L-W; Weinert, M; Weinstein, A J; Weiss, R; Welborn, T; Wen, L; Weßels, P; Westphal, T; Wette, K; Whelan, J T; White, D J; Whiting, B F; Williams, D; Williams, R D; Williamson, A R; Willis, J L; Willke, B; Wimmer, M H; Winkler, W; Wipf, C C; Wittel, H; Woan, G; Worden, J; Wright, J L; Wu, G; Yablon, J; Yam, W; Yamamoto, H; Yancey, C C; Yap, M J; Yu, H; Yvert, M; Zadrożny, A; Zangrando, L; Zanolin, M; Zendri, J-P; Zevin, M; Zhang, F; Zhang, L; Zhang, M; Zhang, Y; Zhao, C; Zhou, M; Zhou, Z; Zhu, X J; Zucker, M E; Zuraw, S E; Zweizig, J; Boyle, M; Campanelli, M; Hemberger, D A; Kidder, L E; Ossokine, S; Scheel, M A; Szilagyi, B; Teukolsky, S; Zlochower, Y

    2016-06-01

    The LIGO detection of GW150914 provides an unprecedented opportunity to study the two-body motion of a compact-object binary in the large-velocity, highly nonlinear regime, and to witness the final merger of the binary and the excitation of uniquely relativistic modes of the gravitational field. We carry out several investigations to determine whether GW150914 is consistent with a binary black-hole merger in general relativity. We find that the final remnant's mass and spin, as determined from the low-frequency (inspiral) and high-frequency (postinspiral) phases of the signal, are mutually consistent with the binary black-hole solution in general relativity. Furthermore, the data following the peak of GW150914 are consistent with the least-damped quasinormal mode inferred from the mass and spin of the remnant black hole. By using waveform models that allow for parametrized general-relativity violations during the inspiral and merger phases, we perform quantitative tests on the gravitational-wave phase in the dynamical regime and we determine the first empirical bounds on several high-order post-Newtonian coefficients. We constrain the graviton Compton wavelength, assuming that gravitons are dispersed in vacuum in the same way as particles with mass, obtaining a 90%-confidence lower bound of 10^{13}  km. In conclusion, within our statistical uncertainties, we find no evidence for violations of general relativity in the genuinely strong-field regime of gravity. PMID:27314708

  2. Does Physics Need Special and General Relativity?

    NASA Astrophysics Data System (ADS)

    Dunning-Davies, Jeremy

    Here it is intended to reconsider briefly some of the objections which have arisen over the years to both the Special and General Theories of Relativity before raising the question of whether or not either of these two theories is actually required by modern physics.

  3. Prevalence of dissociative disorders among women in the general population.

    PubMed

    Sar, Vedat; Akyüz, Gamze; Doğan, Orhan

    2007-01-15

    This study sought to determine the prevalence of dissociative disorders among women in the general population, as assessed in a representative sample of a city in central Turkey. The Dissociative Disorders Interview Schedule (DDIS), the Borderline Personality Disorder section of the Structured Clinical Interview for DSM-III-R Personality Disorders (SCID-II), and the PTSD-Module of the Structured Clinical Interview for DSM-III-R (SCID) were administered to 628 women in 500 homes. The mean age of participants was 34.8 (S.D.=11.5, range: 18-65); 18.3% of participants (n=115) had a lifetime diagnosis of a dissociative disorder. Dissociative disorder not otherwise specified (DDNOS) was the most prevalent diagnosis (8.3%); 1.1% of the population was diagnosed as having dissociative identity disorder (DID). Participants with a dissociative disorder had borderline personality disorder, somatization disorder, major depression, PTSD, and history of suicide attempt more frequently than did participants without a dissociative disorder. Childhood sexual abuse, physical neglect, and emotional abuse were significant predictors of a dissociative disorder diagnosis. Only 28.7% of the dissociative participants had received psychiatric treatment previously. Because dissociative disorders are trauma-related, significant part of the adult clinical consequences of childhood trauma remains obscure in the minds of mental health professionals and of the overall community. Revisions in diagnostic criteria of dissociative disorders in the DSM-IV are recommended.

  4. The Confrontation between General Relativity and Experiment

    NASA Astrophysics Data System (ADS)

    Will, Clifford M.

    2014-12-01

    The status of experimental tests of general relativity and of theoretical frameworks for analyzing them is reviewed and updated. Einstein’s equivalence principle (EEP) is well supported by experiments such as the Eötvös experiment, tests of local Lorentz invariance and clock experiments. Ongoing tests of EEP and of the inverse square law are searching for new interactions arising from unification or quantum gravity. Tests of general relativity at the post-Newtonian level have reached high precision, including the light deflection, the Shapiro time delay, the perihelion advance of Mercury, the Nordtvedt effect in lunar motion, and frame-dragging. Gravitational wave damping has been detected in an amount that agrees with general relativity to better than half a percent using the Hulse-Taylor binary pulsar, and a growing family of other binary pulsar systems is yielding new tests, especially of strong-field effects. Current and future tests of relativity will center on strong gravity and gravitational waves.

  5. Dynamical and Hamiltonian Formulation of General Relativity

    NASA Astrophysics Data System (ADS)

    Giulini, Domenico

    Einstein's theory of General Relativity describes spacetime as a solution of a set of non-linear partial differential equations. These equations are initially not in the form of evolution equations and it is hence not clear how to formulate and solve initial-value problems, as would be physically highly desirable. In this contribution it will be shown how to cast Einstein's equations into the form of a constrained Hamiltonian system. This will allow to formulate and solve initial-value problems, integrate Einstein's equations by numerical codes, characterize dynamical degrees of freedom, and characterize isolated systems and their conserved quantities, like energy, momentum, and angular momentum. Moreover, this reformulation of General Relativity is also the starting point for various attempts to subject the gravitational field to the program of canonical quantization. The exposition given here is, to some degree, self contained. It attempts to comprehensively account for all the relevant geometric constructions, including the relevant symplectic geometry of constrained Hamiltonian systems.

  6. Confronting general relativity with further cosmological data

    SciTech Connect

    Daniel, Scott F.; Linder, Eric V.

    2010-11-15

    Deviations from general relativity in order to explain cosmic acceleration generically have both time and scale-dependent signatures in cosmological data. We extend our previous work by investigating model-independent gravitational deviations in bins of redshift and length scale, by incorporating further cosmological probes such as temperature-galaxy and galaxy-galaxy cross-correlations, and by examining correlations between deviations. Markov Chain Monte Carlo likelihood analysis of the model-independent parameters fitting current data indicates that at low redshift general relativity deviates from the best fit at the 99% confidence level. We trace this to two different properties of the CFHTLS weak lensing data set and demonstrate that COSMOS weak lensing data does not show such deviation. Upcoming galaxy survey data will greatly improve the ability to test time and scale-dependent extensions to gravity and we calculate the constraints that the BigBOSS galaxy redshift survey could enable.

  7. Modeling the brain morphology distribution in the general aging population

    NASA Astrophysics Data System (ADS)

    Huizinga, W.; Poot, D. H. J.; Roshchupkin, G.; Bron, E. E.; Ikram, M. A.; Vernooij, M. W.; Rueckert, D.; Niessen, W. J.; Klein, S.

    2016-03-01

    Both normal aging and neurodegenerative diseases such as Alzheimer's disease cause morphological changes of the brain. To better distinguish between normal and abnormal cases, it is necessary to model changes in brain morphology owing to normal aging. To this end, we developed a method for analyzing and visualizing these changes for the entire brain morphology distribution in the general aging population. The method is applied to 1000 subjects from a large population imaging study in the elderly, from which 900 were used to train the model and 100 were used for testing. The results of the 100 test subjects show that the model generalizes to subjects outside the model population. Smooth percentile curves showing the brain morphology changes as a function of age and spatiotemporal atlases derived from the model population are publicly available via an interactive web application at agingbrain.bigr.nl.

  8. Probing the Higgs vacuum with general relativity

    NASA Technical Reports Server (NTRS)

    Mannheim, Philip D.; Kazanas, Demosthenes

    1991-01-01

    It is shown that the structure of the Higgs vacuum can be revealed in gravitational experiments which probe the Schwarzschild geometry to only one order in MG/r beyond that needed for the classical tests of general relativity. The possibility that deviations from the conventional geometry are at least theoretically conceivable is explored. The deviations obtained provide a diagnostic test for searching for the existence of macroscopic scalar fields and open up the possiblity for further exploring the Higgs mechanism.

  9. Pure connection action principle for general relativity.

    PubMed

    Krasnov, Kirill

    2011-06-24

    It has already been known for two decades that general relativity can be reformulated as a certain gauge theory, so that the only dynamical field is an SO(3) connection and the spacetime metric appears as a derived object. However, no simple action principle realizing these ideas has been available. A new elegant action principle for such a "pure connection" formulation of GR is described.

  10. Generalized population models and the nature of genetic drift.

    PubMed

    Der, Ricky; Epstein, Charles L; Plotkin, Joshua B

    2011-09-01

    The Wright-Fisher model of allele dynamics forms the basis for most theoretical and applied research in population genetics. Our understanding of genetic drift, and its role in suppressing the deterministic forces of Darwinian selection has relied on the specific form of sampling inherent to the Wright-Fisher model and its diffusion limit. Here we introduce and analyze a broad class of forward-time population models that share the same mean and variance as the Wright-Fisher model, but may otherwise differ. The proposed class unifies and further generalizes a number of population-genetic processes of recent interest, including the Λ and Cannings processes. Even though these models all have the same variance effective population size, they encode a rich diversity of alternative forms of genetic drift, with significant consequences for allele dynamics. We characterize in detail the behavior of standard population-genetic quantities across this family of generalized models. Some quantities, such as heterozygosity, remain unchanged; but others, such as neutral absorption times and fixation probabilities under selection, deviate by orders of magnitude from the Wright-Fisher model. We show that generalized population models can produce startling phenomena that differ qualitatively from classical behavior - such as assured fixation of a new mutant despite the presence of genetic drift. We derive the forward-time continuum limits of the generalized processes, analogous to Kimura's diffusion limit of the Wright-Fisher process, and we discuss their relationships to the Kingman and non-Kingman coalescents. Finally, we demonstrate that some non-diffusive, generalized models are more likely, in certain respects, than the Wright-Fisher model itself, given empirical data from Drosophila populations.

  11. Worldwide Estimates Relative to Five Continental-Scale Populations

    PubMed Central

    Steele, Christopher D; Court, Denise Syndercombe; Balding, David J

    2014-01-01

    We estimate the population genetics parameter (also referred to as the fixation index) from short tandem repeat (STR) allele frequencies, comparing many worldwide human subpopulations at approximately the national level with continental-scale populations. is commonly used to measure population differentiation, and is important in forensic DNA analysis to account for remote shared ancestry between a suspect and an alternative source of the DNA. We estimate comparing subpopulations with a hypothetical ancestral population, which is the approach most widely used in population genetics, and also compare a subpopulation with a sampled reference population, which is more appropriate for forensic applications. Both estimation methods are likelihood-based, in which is related to the variance of the multinomial-Dirichlet distribution for allele counts. Overall, we find low values, with posterior 97.5 percentiles when comparing a subpopulation with the most appropriate population, and even for inter-population comparisons we find . These are much smaller than single nucleotide polymorphism-based inter-continental estimates, and are also about half the magnitude of STR-based estimates from population genetics surveys that focus on distinct ethnic groups rather than a general population. Our findings support the use of up to 3% in forensic calculations, which corresponds to some current practice. PMID:26460400

  12. Evolutionary dynamics of general group interactions in structured populations

    NASA Astrophysics Data System (ADS)

    Li, Aming; Broom, Mark; Du, Jinming; Wang, Long

    2016-02-01

    The evolution of populations is influenced by many factors, and the simple classical models have been developed in a number of important ways. Both population structure and multiplayer interactions have been shown to significantly affect the evolution of important properties, such as the level of cooperation or of aggressive behavior. Here we combine these two key factors and develop the evolutionary dynamics of general group interactions in structured populations represented by regular graphs. The traditional linear and threshold public goods games are adopted as models to address the dynamics. We show that for linear group interactions, population structure can favor the evolution of cooperation compared to the well-mixed case, and we see that the more neighbors there are, the harder it is for cooperators to persist in structured populations. We further show that threshold group interactions could lead to the emergence of cooperation even in well-mixed populations. Here population structure sometimes inhibits cooperation for the threshold public goods game, where depending on the benefit to cost ratio, the outcomes are bistability or a monomorphic population of defectors or cooperators. Our results suggest, counterintuitively, that structured populations are not always beneficial for the evolution of cooperation for nonlinear group interactions.

  13. Evolutionary dynamics of general group interactions in structured populations.

    PubMed

    Li, Aming; Broom, Mark; Du, Jinming; Wang, Long

    2016-02-01

    The evolution of populations is influenced by many factors, and the simple classical models have been developed in a number of important ways. Both population structure and multiplayer interactions have been shown to significantly affect the evolution of important properties, such as the level of cooperation or of aggressive behavior. Here we combine these two key factors and develop the evolutionary dynamics of general group interactions in structured populations represented by regular graphs. The traditional linear and threshold public goods games are adopted as models to address the dynamics. We show that for linear group interactions, population structure can favor the evolution of cooperation compared to the well-mixed case, and we see that the more neighbors there are, the harder it is for cooperators to persist in structured populations. We further show that threshold group interactions could lead to the emergence of cooperation even in well-mixed populations. Here population structure sometimes inhibits cooperation for the threshold public goods game, where depending on the benefit to cost ratio, the outcomes are bistability or a monomorphic population of defectors or cooperators. Our results suggest, counterintuitively, that structured populations are not always beneficial for the evolution of cooperation for nonlinear group interactions. PMID:26986362

  14. Strongly magnetized rotating dipole in general relativity

    NASA Astrophysics Data System (ADS)

    Pétri, J.

    2016-10-01

    Context. Electromagnetic waves arise in many areas of physics. Solutions are difficult to find in the general case. Aims: We numerically integrate Maxwell equations in a 3D spherical polar coordinate system. Methods: Straightforward finite difference methods would lead to a coordinate singularity along the polar axis. Spectral methods are better suited for such artificial singularities that are related to the choice of a coordinate system. When the radiating object rotates like a star, for example, special classes of solutions to Maxwell equations are worthwhile to study, such as quasi-stationary regimes. Moreover, in high-energy astrophysics, strong gravitational and magnetic fields are present especially around rotating neutron stars. Results: To study such systems, we designed an algorithm to solve the time-dependent Maxwell equations in spherical polar coordinates including general relativity and quantum electrodynamical corrections to leading order. As a diagnostic, we computed the spin-down luminosity expected for these stars and compared it to the classical or non-relativistic and non-quantum mechanical results. Conclusions: Quantum electrodynamics leads to an irrelevant change in the spin-down luminosity even for a magnetic field of about the critical value of 4.4 × 109 T. Therefore the braking index remains close to its value for a point dipole in vacuum, namely n = 3. The same conclusion holds for a general-relativistic quantum electrodynamically corrected force-free magnetosphere.

  15. General relativity and cosmic structure formation

    NASA Astrophysics Data System (ADS)

    Adamek, Julian; Daverio, David; Durrer, Ruth; Kunz, Martin

    2016-04-01

    Numerical simulations are a versatile tool for providing insight into the complicated process of structure formation in cosmology. This process is mainly governed by gravity, which is the dominant force on large scales. At present, a century after the formulation of general relativity, numerical codes for structure formation still employ Newton’s law of gravitation. This approximation relies on the two assumptions that gravitational fields are weak and that they originate from non-relativistic matter. Whereas the former seems well justified on cosmological scales, the latter imposes restrictions on the nature of the `dark’ components of the Universe (dark matter and dark energy), which are, however, poorly understood. Here we present the first simulations of cosmic structure formation using equations consistently derived from general relativity. We study in detail the small relativistic effects for a standard lambda cold dark matter cosmology that cannot be obtained within a purely Newtonian framework. Our particle-mesh N-body code computes all six degrees of freedom of the metric and consistently solves the geodesic equation for particles, taking into account the relativistic potentials and the frame-dragging force. This conceptually clean approach is very general and can be applied to various settings where the Newtonian approximation fails or becomes inaccurate, ranging from simulations of models with dynamical dark energy or warm/hot dark matter to core collapse supernova explosions.

  16. Defining forgiveness: christian clergy and general population perspectives.

    PubMed

    Macaskill, Ann

    2005-10-01

    The lack of any consensual definition of forgiveness is a serious weakness in the research literature (McCullough, Pargament, & Thoresen, 2000). As forgiveness is at the core of Christianity, this study returns to the Christian source of the concept to explore the meaning of forgiveness for practicing Christian clergy. Comparisons are made with a general population sample and social science definitions of forgiveness to ensure that a shared meaning of forgiveness is articulated. Anglican and Roman Catholic clergy (N = 209) and a general population sample (N = 159) completed a postal questionnaire about forgiveness. There was agreement on the existence of individual differences in forgiveness. Clergy and the general population perceived reconciliation as necessary for forgiveness while there was no consensus within psychology. The clergy suggest that forgiveness is limitless and that repentance is unnecessary, while the general population suggests that there are limits and that repentance is necessary. Psychological definitions do not conceptualize repentance as necessary for forgiveness, and the question of limits has not been addressed, although, within therapy, the implicit assumption is that forgiveness is limitless.

  17. Generalizing in Interaction: Middle School Mathematics Students Making Mathematical Generalizations in a Population-Modeling Project

    ERIC Educational Resources Information Center

    Jurow, A. Susan

    2004-01-01

    Generalizing or making claims that extend beyond particular situations is a central mathematical practice and a focus of classroom mathematics instruction. This study examines how aspects of generality are produced through the situated activities of a group of middle school mathematics students working on an 8-week population-modeling project. The…

  18. New Area Law in General Relativity.

    PubMed

    Bousso, Raphael; Engelhardt, Netta

    2015-08-21

    We report a new area law in general relativity. A future holographic screen is a hypersurface foliated by marginally trapped surfaces. We show that their area increases monotonically along the foliation. Future holographic screens can easily be found in collapsing stars and near a big crunch. Past holographic screens exist in any expanding universe and obey a similar theorem, yielding the first rigorous area law in big bang cosmology. Unlike event horizons, these objects can be identified at finite time and without reference to an asymptotic boundary. The Bousso bound is not used, but it naturally suggests a thermodynamic interpretation of our result.

  19. New Area Law in General Relativity

    NASA Astrophysics Data System (ADS)

    Bousso, Raphael; Engelhardt, Netta

    2015-08-01

    We report a new area law in general relativity. A future holographic screen is a hypersurface foliated by marginally trapped surfaces. We show that their area increases monotonically along the foliation. Future holographic screens can easily be found in collapsing stars and near a big crunch. Past holographic screens exist in any expanding universe and obey a similar theorem, yielding the first rigorous area law in big bang cosmology. Unlike event horizons, these objects can be identified at finite time and without reference to an asymptotic boundary. The Bousso bound is not used, but it naturally suggests a thermodynamic interpretation of our result.

  20. New Area Law in General Relativity.

    PubMed

    Bousso, Raphael; Engelhardt, Netta

    2015-08-21

    We report a new area law in general relativity. A future holographic screen is a hypersurface foliated by marginally trapped surfaces. We show that their area increases monotonically along the foliation. Future holographic screens can easily be found in collapsing stars and near a big crunch. Past holographic screens exist in any expanding universe and obey a similar theorem, yielding the first rigorous area law in big bang cosmology. Unlike event horizons, these objects can be identified at finite time and without reference to an asymptotic boundary. The Bousso bound is not used, but it naturally suggests a thermodynamic interpretation of our result. PMID:26340179

  1. Epicycles and Poincare resonances in general relativity

    SciTech Connect

    Koekoek, G.; Holten, J. W. van

    2011-03-15

    The method of geodesic deviations provides analytic approximations to geodesics in arbitrary background space-times. As such the method is a useful tool in many practical situations. In this paper we construct an improved parametrized version of the method, and discuss some subtleties in its application related to secular motions in first as well as in higher-order. In particular we work out the general second-order contribution to bound orbits in Schwarzschild space-time and show that it provides very good analytical results all the way up to the innermost stable circular orbit.

  2. Alcohol Drinking Pattern: A Comparison between HIV-Infected Patients and Individuals from the General Population

    PubMed Central

    Ikeda, Maria Leticia R.; Barcellos, Nemora T.; Alencastro, Paulo R.; Wolff, Fernando H.; Moreira, Leila B.; Gus, Miguel; Brandão, Ajacio B. M.; Fuchs, Flavio D.; Fuchs, Sandra C.

    2016-01-01

    Background Alcohol consumption is highly prevalent in the general population and among HIV-infected population. This study aimed to compare the pattern of alcohol consumption and to describe characteristics associated with heavy alcohol consumption in individuals from the general population with patients infected with HIV. Methods Participants for this analysis came from a population-based cross-sectional study and from a consecutive sampling of patients infected with HIV. Participants aged 18 years or older were interviewed using similar questionnaires with questions pertaining to socio-demographic characteristics, alcohol consumption, smoking, physical activity, and HIV-related characteristics, among others. Blood pressure and anthropometric measures were measured using standardized procedures. Results Weekly alcohol consumption was more prevalent among individuals from the general population than HIV-infected patients: 57.0 vs. 31.1%, P<0.001. The prevalence of heavy episodic drinking was higher in the population sample as well: 46.1 vs. 17.0%, P<0.001. In the general population, heavy alcohol consumption was more prevalent in men. Cigarette smoking was independently associated with heavy alcohol consumption among HIV infected (Prevalence Ratio; PR = 5.9; 95%CI 2.6–13.9; P<0,001) and general population (PR = 2.6; 95%CI 1.9–3.0; P<0.001). Years at school were inversely associated with heavy alcohol consumption among HIV-infected patients and directly associated among participants from the general population, even after controlling for sex, age, skin color, and smoking. Conclusions Heavy alcohol consumption is more prevalent in the general population than among HIV-infected patients. Individuals aware about their disease may reduce the amount of alcoholic beverages consumption comparatively to healthy individuals from the general population. PMID:27362541

  3. Uncertainty relations for general unitary operators

    NASA Astrophysics Data System (ADS)

    Bagchi, Shrobona; Pati, Arun Kumar

    2016-10-01

    We derive several uncertainty relations for two arbitrary unitary operators acting on physical states of a Hilbert space. We show that our bounds are tighter in various cases than the ones existing in the current literature. Using the uncertainty relation for the unitary operators, we obtain the tight state-independent lower bound for the uncertainty of two Pauli observables and anticommuting observables in higher dimensions. With regard to the minimum-uncertainty states, we derive the minimum-uncertainty state equation by the analytic method and relate this to the ground-state problem of the Harper Hamiltonian. Furthermore, the higher-dimensional limit of the uncertainty relations and minimum-uncertainty states are explored. From an operational point of view, we show that the uncertainty in the unitary operator is directly related to the visibility of quantum interference in an interferometer where one arm of the interferometer is affected by a unitary operator. This shows a principle of preparation uncertainty, i.e., for any quantum system, the amount of visibility for two general noncommuting unitary operators is nontrivially upper bounded.

  4. General Health of Foreign-Origin Groups and Native Population

    PubMed Central

    Ardian, Nahid; Mahmoudabad, Seyed Saeid Mazloomy; Ardian, Mahdi; Karimi, Masoud

    2014-01-01

    Background: Since the mental health of marginal settlers (non-native population) may affect other citizens’ health, the present study attempts to investigate the mental health status of marginal settlers of Yazd. Materials and Methods: this study was a descriptive, cross-sectional research, in which 400 of non-native and native population have participated. To study mental health status of people, a questionnaire was used. The first section of this questionnaire was the 28-item questionnaire of GHQ and the second section dealt with demographic characteristics such as age, sex, employment status, household income, and educational level of the father of the family. The collected data was analyzed using statistical operations of Pearson correlation coefficient, T Student, univariate Anova, and non-parametric Chi Square. Results: The results revealed that the average scores of general health were 20.09±9.84 and 17.04±9.54 for native and non-native population, respectively. Among subscales of general health, the highest and lowest average scores belonged to social dysfunctions, which showed a dangerous mental health status, and depression, respectively. There was significant difference between average score of general health and educational level of the father of the family (p<.001). The temporary employment and leased household differs significantly from the average score of general health among native population. It was indicated that sex was one of the most powerful predictors of mental health and people had more mental health when they grew older. Anxiety was the strongest predictor of general health for both groups. Conclusion: It seems that background factors such as educational level and employment status effect general health of people more than living in marginal settlement. PMID:25168986

  5. Generalized nonholonomic mechanics, servomechanisms and related brackets

    NASA Astrophysics Data System (ADS)

    Cendra, H.; Grillo, S.

    2006-02-01

    It is well known that nonholonomic systems obeying D'Alembert's principle are described on the Hamiltonian side, after using the Legendre transformation, by the so-called almost-Poisson brackets. In this paper we define the Lagrangian and Hamiltonian sides of a class of generalized nonholonomic systems (GNHS), obeying a generalized version of D'Alembert's principle, such as rubber wheels (like some simplified models of pneumatic tires) and certain servomechanisms (like the controlled inverted pendulum), and show that corresponding equations of motion can also be described in terms of a bracket. We present essentially all possible brackets in terms of which the mentioned equations can be written down, which include the brackets that appear in the literature, and point out those (if any) that are naturally related to each system. In particular, we show there always exists a Leibniz bracket related to a GNHS, and conversely, that every Leibniz system is a GNHS. The control of the inverted pendulum on a cart is studied as an illustrative example.

  6. Nuclear Quantum Gravitation and General Relativity Compared

    NASA Astrophysics Data System (ADS)

    Kotas, Ronald

    2006-04-01

    Nuclear Quantum Gravitation has 18 proofs and indications with a reasonable, non-fallacious explanation stating Gravity and Gravitation are electromagnetic and alternating, functioning in nuclei and alternating electromagnetic coupling between nuclei and other nuclei in other masses. This is according to Maxwell, Quantum, and Newtonian Laws. Nuclear Quantum Gravitation passes the Cavendish test. With the 18 proofs and indications of NQG it is clear that Gravity and Gravitation are electromagnetic and thoroughly explained by the Nuclear Quantum Gravitation theory. In comparison, General Relativity pictures mass somehow effects ``Time-Space'' about the mass, producing gravity about that mass. This is not described as an electromagnetic effect, but as a geometric function; the changing of geometry about mass. GR lists as a proof the bending of light in the area near the Sun. However, recently it was observed that the temperature of the Sun's corona is in the millions of degrees, and thus the bending of light and other electromagnetic radiation is caused by the refraction effects of the corona and heliosphere; NOT GR. The other ``proofs'' of GR are not definitive, and no one has yet explained the ``somehow'' of GR. General Relativity fails the Cavendish experiment and cannot account for the attractions between masses. It should be realized that Nuclear Quantum Gravitation provides a coherent, factual, scientific and direct physical explanation of Gravity and Gravitation thus Unifying the Physical Forces.

  7. Impact of obesity-related genes in Spanish population

    PubMed Central

    2013-01-01

    Background The objective was to investigate the association between BMI and single nucleotide polymorphisms previously identified of obesity-related genes in two Spanish populations. Forty SNPs in 23 obesity-related genes were evaluated in a rural population characterized by a high prevalence of obesity (869 subjects, mean age 46 yr, 62% women, 36% obese) and in an urban population (1425 subjects, mean age 54 yr, 50% women, 19% obese). Genotyping was assessed by using SNPlex and PLINK for the association analysis. Results Polymorphisms of the FTO were significantly associated with BMI, in the rural population (beta 0.87, p-value <0.001). None of the other SNPs showed significant association after Bonferroni correction in the two populations or in the pooled analysis. A weighted genetic risk score (wGRS) was constructed using the risk alleles of the Tag-SNPs with a positive Beta parameter in both populations. From the first to the fifth quintile of the score, the BMI increased 0.45 kg/m2 in Hortega and 2.0 kg/m2 in Pizarra. Overall, the obesity predictive value was low (less than 1%). Conclusion The risk associated with polymorphisms is low and the overall effect on BMI or obesity prediction is minimal. A weighted genetic risk score based on genes mainly acting through central nervous system mechanisms was associated with BMI but it yields minimal clinical prediction for the obesity risk in the general population. PMID:24267414

  8. Rapidly rotating polytropes in general relativity

    NASA Technical Reports Server (NTRS)

    Cook, Gregory B.; Shapiro, Stuart L.; Teukolsky, Saul A.

    1994-01-01

    We construct an extensive set of equilibrium sequences of rotating polytropes in general relativity. We determine a number of important physical parameters of such stars, including maximum mass and maximum spin rate. The stability of the configurations against quasi-radial perturbations is diagnosed. Two classes of evolutionary sequences of fixed rest mass and entropy are explored: normal sequences which behave very much like Newtonian evolutionary sequences, and supramassive sequences which exist solely because of relativistic effects. Dissipation leading to loss of angular momentum causes a star to evolve in a quasi-stationary fashion along an evolutionary sequence. Supramassive sequences evolve towards eventual catastrophic collapse to a black hole. Prior to collapse, the star must spin up as it loses angular momentum, an effect which may provide an observational precursor to gravitational collapse to a black hole.

  9. On thick domain walls in general relativity

    NASA Technical Reports Server (NTRS)

    Goetz, Guenter; Noetzold, Dirk

    1989-01-01

    Planar scalar field configurations in general relativity differ considerably from those in flat space. It is shown that static domain walls of finite thickness in curved space-time do not possess a reflection symmetry. At infinity, the space-time tends to the Taub vacuum on one side of the wall and to the Minkowski vacuum (Rindler space-time) on the other. Massive test particles are always accelerated towards the Minkowski side, i.e., domain walls are attractive on the Taub side, but repulsive on the Minkowski side (Taub-vacuum cleaner). It is also proved that the pressure in all directions is always negative. Finally, a brief comment is made concerning the possibility of infinite, i.e., bigger than horizon size, domain walls in our universe. All of the results are independent of the form of the potential V(phi) greater than or equal to 0 of the scalar field phi.

  10. Motivations for antigravity in General Relativity

    NASA Astrophysics Data System (ADS)

    Chardin, G.

    1997-08-01

    We present arguments showing that it is natural to interpret the negative mass part of the Kerr solution as representing the geometry experienced by antimatter. The C, P and T discrete transformations are considered for this geometry. The C and T properties of the proposed identification are found to be in agreement with the usual representation of antimatter. In addition, we conjecture a property of perfect stigmatism through Kerr wormholes which allows General Relativity to mimic antigravity. Kerr wormholes would then act as “supermirrors” reversing the C, P and T images of an object seen through it. This interpretation is subject to several experimental tests and able to provide an explanation, without any free parameter, of the “CP” violation observed in the neutral kaon system.

  11. The confrontation between general relativity and experiment

    NASA Technical Reports Server (NTRS)

    Will, C. M.

    1980-01-01

    Experiments that test the foundations of gravitation theory in terms of the Einstein equivalence principle are discussed along with solar system tests of general relativity at the post-Newtonian level. These include classical (light-deflection, time delay and perihelion shift) tests as well as tests of the strong equivalence principle. The binary pulsar is discussed as an extra-solar-system gravitational testing ground, and attention is given to the multipolarity of the waves and the amount of radiation damping. The mass function, periastron shift, redshift-Doppler parameter and rate of change of the orbit period (Pb) of the binary pulsar are also considered, and it is suggested that the measurement of Pb represents the first observation of the effects of gravitational radiation.

  12. General relativity from a thermodynamic perspective

    NASA Astrophysics Data System (ADS)

    Padmanabhan, T.

    2014-03-01

    I show that the gravitational dynamics in a bulk region of space can be connected to a thermodynamic description in the boundary of that region, thereby providing clear physical interpretations of several mathematical features of classical general relativity: (1) The Noether charge contained in a bulk region, associated with a specific time evolution vector field, has a direct thermodynamic interpretation as the gravitational heat content of the boundary surface. (2) This result, in turn, shows that all static spacetimes maintain holographic equipartition in the following sense: In these spacetimes, the number of degrees of freedom in the boundary is equal to the number of degrees of freedom in the bulk. (3) In a general, evolving spacetime, the rate of change of gravitational momentum is related to the difference between the number of bulk and boundary degrees of freedom. It is this departure from the holographic equipartition which drives the time evolution of the spacetime. (4) When the equations of motion hold, the (naturally defined) total energy of the gravity plus matter within a bulk region, will be equal to the boundary heat content. (5) After motivating the need for an alternate description of gravity (if we have to solve the cosmological constant problem), I describe a thermodynamic variational principle based on null surfaces to achieve this goal. The concept of gravitational heat density of the null surfaces arises naturally from the Noether charge associated with the null congruence. The variational principle, in fact, extremises the total heat content of the matter plus gravity system. Several variations on this theme and implications are described.

  13. An Introduction to General Relativity and Cosmology

    NASA Astrophysics Data System (ADS)

    Plebanski, Jerzy; Krasinski, Andrzej

    2012-09-01

    1. How the theory of relativity came into being (a brief historical sketch); Part I. Elements of Differential Geometry: 2. A short sketch of two-dimensional differential geometries; 3. Tensors, tensor densities; 4. Covariant derivatives; 5. Parallel transport and geodesic lines; 6. Curvature of a manifold: flat manifolds; 7. Riemannian geometry; 8. Symmetries of Rieman spaces, invariance of tensors; 9. Methods to calculate the curvature quickly - Cartan forms and algebraic computer programs; 10. The spatially homogeneous Bianchi-type spacetimes; 11. The Petrov classification by the spinor method; Part II. The Gravitation Theory: 12. The Einstein equations and the sources of a gravitational field; 13. The Maxwell and Einstein-Maxwell equations and the Kaluza-Klein theory; 14. Spherically symmetric gravitational field of isolated objects; 15. Relativistic hydrodynamics and thermodynamics; 16. Relativistic cosmology I: general geometry; 17. Relativistic cosmology II: the Robertson-Walker geometry; 18. Relativistic cosmology III: the Lemaître-Tolman geometry; 19. Relativistic cosmology IV: generalisations of L-T and related geometries; 20. The Kerr solution; 21. Subjects omitted in this book; References.

  14. Predictors for mortality from respiratory failure in a general population

    PubMed Central

    Kobayashi, Maki; Shibata, Yoko; Inoue, Sumito; Igarashi, Akira; Sato, Kento; Sato, Masamichi; Nemoto, Takako; Abe, Yuki; Nunomiya, Keiko; Nishiwaki, Michiko; Tokairin, Yoshikane; Kimura, Tomomi; Daimon, Makoto; Makino, Naohiko; Watanabe, Tetsu; Konta, Tsuneo; Ueno, Yoshiyuki; Kato, Takeo; Kayama, Takamasa; Kubota, Isao

    2016-01-01

    Risk factors for death from respiratory failure in the general population are not established. The aim of this study was to determine the characteristics of individuals who die of respiratory failure in a Japanese general population. In total, 3253 adults aged 40 years or older participated in annual health check in Takahata, Yamagata, Japan from 2004 to 2006. Subject deaths through the end of 2010 were reviewed; 27 subjects died of respiratory failure (pneumonia, n = 22; COPD, n = 1; pulmonary fibrosis, n = 3; and bronchial asthma, n = 1). Cox proportional hazard analysis revealed that male sex; higher age, high levels of D-dimer and fibrinogen; lower body mass index (BMI) and total cholesterol; and history of stroke and gastric ulcer were independent risk factors for respiratory death. On analysis with C-statistics, net reclassification improvement, and integrated discrimination improvement, addition of the disease history and laboratory data significantly improved the model prediction for respiratory death using age and BMI. In conclusion, we identified risk factors for mortality from respiratory failure in a prospective cohort of a Japanese general population. Men who were older, underweight, hypocholesterolemic, hypercoagulo-fibrinolytic, and had a history of stroke or gastric ulcer had a higher risk of mortality due to respiratory failure. PMID:27180927

  15. Predictors for mortality from respiratory failure in a general population.

    PubMed

    Kobayashi, Maki; Shibata, Yoko; Inoue, Sumito; Igarashi, Akira; Sato, Kento; Sato, Masamichi; Nemoto, Takako; Abe, Yuki; Nunomiya, Keiko; Nishiwaki, Michiko; Tokairin, Yoshikane; Kimura, Tomomi; Daimon, Makoto; Makino, Naohiko; Watanabe, Tetsu; Konta, Tsuneo; Ueno, Yoshiyuki; Kato, Takeo; Kayama, Takamasa; Kubota, Isao

    2016-01-01

    Risk factors for death from respiratory failure in the general population are not established. The aim of this study was to determine the characteristics of individuals who die of respiratory failure in a Japanese general population. In total, 3253 adults aged 40 years or older participated in annual health check in Takahata, Yamagata, Japan from 2004 to 2006. Subject deaths through the end of 2010 were reviewed; 27 subjects died of respiratory failure (pneumonia, n = 22; COPD, n = 1; pulmonary fibrosis, n = 3; and bronchial asthma, n = 1). Cox proportional hazard analysis revealed that male sex; higher age, high levels of D-dimer and fibrinogen; lower body mass index (BMI) and total cholesterol; and history of stroke and gastric ulcer were independent risk factors for respiratory death. On analysis with C-statistics, net reclassification improvement, and integrated discrimination improvement, addition of the disease history and laboratory data significantly improved the model prediction for respiratory death using age and BMI. In conclusion, we identified risk factors for mortality from respiratory failure in a prospective cohort of a Japanese general population. Men who were older, underweight, hypocholesterolemic, hypercoagulo-fibrinolytic, and had a history of stroke or gastric ulcer had a higher risk of mortality due to respiratory failure. PMID:27180927

  16. BOOK REVIEW: Modern Canonical Quantum General Relativity

    NASA Astrophysics Data System (ADS)

    Kiefer, Claus

    2008-06-01

    The open problem of constructing a consistent and experimentally tested quantum theory of the gravitational field has its place at the heart of fundamental physics. The main approaches can be roughly divided into two classes: either one seeks a unified quantum framework of all interactions or one starts with a direct quantization of general relativity. In the first class, string theory (M-theory) is the only known example. In the second class, one can make an additional methodological distinction: while covariant approaches such as path-integral quantization use the four-dimensional metric as an essential ingredient of their formalism, canonical approaches start with a foliation of spacetime into spacelike hypersurfaces in order to arrive at a Hamiltonian formulation. The present book is devoted to one of the canonical approaches—loop quantum gravity. It is named modern canonical quantum general relativity by the author because it uses connections and holonomies as central variables, which are analogous to the variables used in Yang Mills theories. In fact, the canonically conjugate variables are a holonomy of a connection and the flux of a non-Abelian electric field. This has to be contrasted with the older geometrodynamical approach in which the metric of three-dimensional space and the second fundamental form are the fundamental entities, an approach which is still actively being pursued. It is the author's ambition to present loop quantum gravity in a way in which every step is formulated in a mathematically rigorous form. In his own words: 'loop quantum gravity is an attempt to construct a mathematically rigorous, background-independent, non-perturbative quantum field theory of Lorentzian general relativity and all known matter in four spacetime dimensions, not more and not less'. The formal Leitmotiv of loop quantum gravity is background independence. Non-gravitational theories are usually quantized on a given non-dynamical background. In contrast, due to

  17. Sample and population exponents of generalized Taylor's law.

    PubMed

    Giometto, Andrea; Formentin, Marco; Rinaldo, Andrea; Cohen, Joel E; Maritan, Amos

    2015-06-23

    Taylor's law (TL) states that the variance V of a nonnegative random variable is a power function of its mean M; i.e., V = aM(b). TL has been verified extensively in ecology, where it applies to population abundance, physics, and other natural sciences. Its ubiquitous empirical verification suggests a context-independent mechanism. Sample exponents b measured empirically via the scaling of sample mean and variance typically cluster around the value b = 2. Some theoretical models of population growth, however, predict a broad range of values for the population exponent b pertaining to the mean and variance of population density, depending on details of the growth process. Is the widely reported sample exponent b ≃ 2 the result of ecological processes or could it be a statistical artifact? Here, we apply large deviations theory and finite-sample arguments to show exactly that in a broad class of growth models the sample exponent is b ≃ 2 regardless of the underlying population exponent. We derive a generalized TL in terms of sample and population exponents b(jk) for the scaling of the kth vs. the jth cumulants. The sample exponent b(jk) depends predictably on the number of samples and for finite samples we obtain b(jk) ≃ k = j asymptotically in time, a prediction that we verify in two empirical examples. Thus, the sample exponent b ≃ 2 may indeed be a statistical artifact and not dependent on population dynamics under conditions that we specify exactly. Given the broad class of models investigated, our results apply to many fields where TL is used although inadequately understood.

  18. Generalized Entropic Uncertainty Relations with Tsallis' Entropy

    NASA Technical Reports Server (NTRS)

    Portesi, M.; Plastino, A.

    1996-01-01

    A generalization of the entropic formulation of the Uncertainty Principle of Quantum Mechanics is considered with the introduction of the q-entropies recently proposed by Tsallis. The concomitant generalized measure is illustrated for the case of phase and number operators in quantum optics. Interesting results are obtained when making use of q-entropies as the basis for constructing generalized entropic uncertainty measures.

  19. Directions in General Relativity, Vol. 2

    NASA Astrophysics Data System (ADS)

    Hu, B. L.; Jacobson, T. A.

    2005-10-01

    Preface; Dieter Brill: a spacetime perspective; 1. Thawing the frozen formalism: the difference between observables and what we observe A. Anderson; 2. Jacobi's action and the density of states J. D. Brown and J. W. York; 3. Decoherence of correlation histories E. Calzetta and B. L. Hu; 4. The initial value problem in light of Ashtekar's variables R. Capovilla, J. Dell and T. Jacobson; 5. Status report on an axiomatic basis for functional integration P. Cartier and C. DeWitt-Morette; 6. Solution of the coupled Einstein constraints on asymptotically Euclidean manifolds Y. Choquet-Bruhat; 7. Compact Cauchy horizons and Cauchy surfaces P. Chrusciel and J. Isenberg; 8. The classical electron J. M. Cohen and E. Mustafa; 9. Gauge (in)variance, mass and parity in D=3 revisited S. Deser; 10. Triality, exceptional Lie groups and Dirac operators F. Flaherty; 11. The reduction of the state vector and limitations on measurement in the quantum mechanics of closed systems J. B. Hartle; 12 Quantum linearization instabilities of de Sitter spacetime A. Higuchi; 13. What is the true description of charged black holes? G. T. Horowitz; 14. Limits on the adiabatic index in static stellar models L. Lindblom and A. K. M. Masood-ul-Alam; 15. On the relativity of rotation B. Mashhoon; 16. Recent progress and open problems in linearization stability V. E. Moncrief; 17. Brill waves N. Murchadha; 18. You can't get there from here: constraints on topology change K. Schleich and D. M. Witt; 19. Time, measurement and information loss in quantum cosmology L. Smolin; 20. Impossible measurements on quantum fields R. Sorkin; 21. A new condition implying the existence of a constant mean curvature foliation F. J. Tipler; 22. Maximal slices in stationary spacetimes with ergoregions R. M. Wald; 23. (1 + 1) - Dimensional methods for general relativity J. H. Yoon; 24. Coalescence of primal gravity waves to make cosmological mass without matter D. E. Holz, W. A. Miller, M. Wakano and J. A. Wheeler

  20. Exotic differentiable structures and general relativity

    NASA Astrophysics Data System (ADS)

    Brans, Carl H.; Randall, Duane

    1993-02-01

    We review recent developments in differential topology with special concern for their possible significance to physical theories, especially general relativity. In particular we are concerned here with the discovery of the existence of non-standard (“fake” or “exotic”) differentiable structures on topologically simple manifolds such asS 7, ℝ4 andS 3 X ℝ1. Because of the technical difficulties involved in the smooth case, we begin with an easily understood toy example looking at the role which the choice of complex structures plays in the formulation of two-dimensional vacuum electrostatics. We then briefly review the mathematical formalisms involved with differentiable structures on topological manifolds, diffeomorphisms and their significance for physics. We summarize the important work of Milnor, Freedman, Donaldson, and others in developing exotic differentiable structures on well known topological manifolds. Finally, we discuss some of the geometric implications of these results and propose some conjectures on possible physical implications of these new manifolds which have never before been considered as physical models.

  1. Inflation and bubbles in general relativity

    NASA Astrophysics Data System (ADS)

    Laguna-Castillo, Pablo; Matzner, Richard A.

    1986-11-01

    Following Israel's study of singular hypersurfaces and thin shells in general relativity, the complete set of Einstein's field equations in the presence of a bubble boundary SIGMA is reviewed for all spherically symmetric embedding four-geometries M+/-. The mapping that identifies points between the boundaries Σ+ and Σ- is obtained explicitly when the regions M+ and M- are described by a de Sitter and a Minkowski metric, respectively. In addition, the evolution of a bubble with vanishing surface energy density is studied in a spatially flat Robertson-Walker space-time, for region M- radiation dominated with a vanishing cosmological constant, and an energy equation in M+ determined by the matching. It is found that this type of bubble leads to a ``worm-hole'' matching; that is, an infinite extent exterior of a sphere is joined across the wall to another infinite extent exterior of a sphere. Interior-interior matches are also possible. Under this model, solutions for a bubble following a Hubble law are analyzed. Numerical solutions for bubbles with constant tension are also obtained.

  2. Potential for general relativity and its geometry

    NASA Astrophysics Data System (ADS)

    Gabadadze, Gregory; Hinterbichler, Kurt; Pirtskhalava, David; Shang, Yanwen

    2013-10-01

    The unique ghost-free mass and nonlinear potential terms for general relativity are presented in a diffeomorphism and local Lorentz invariant vierbein formalism. This construction requires an additional two-index Stückelberg field, beyond the four scalar fields used in the metric formulation, and unveils a new local SL(4) symmetry group of the mass and potential terms, not shared by the Einstein-Hilbert term. The new field is auxiliary but transforms as a vector under two different Lorentz groups, one of them the group of local Lorentz transformations, the other an additional global group. This formulation enables a geometric interpretation of the mass and potential terms for gravity in terms of certain volume forms. Furthermore, we find that the decoupling limit is much simpler to extract in this approach; in particular, we are able to derive expressions for the interactions of the vector modes. We also note that it is possible to extend the theory by promoting the two-index auxiliary field into a Nambu-Goldstone boson nonlinearly realizing a certain spacetime symmetry, and show how it is “eaten up” by the antisymmetric part of the vierbein.

  3. Modeling extended fluid objects in general relativity

    NASA Astrophysics Data System (ADS)

    Schiff, Conrad

    The purpose of this dissertation is to introduce and explore the notion of modeling extended fluid objects in numerical general relativity. These extended fluid objects, called Fat Particles, are proxies for compact hydrodynamic objects. Unlike full hydrodynamic models, we make the approximation that the details of the matter distribution are riot as important as the gross motion of the Fat Particles center of mass and its contribution to the gravitational field. Thus we provide a semi-analytic model of matter for numerical simulations of Einstein's equations, which may help in modeling gravitational radiation from candidate sources. Our approach to carrying out these investigations is to begin with a continuum variational principle, which yields the desired hydrodynamic and gravitational equations for ideal fluids. Following our analysis of the related numerical technique, Smoothed Particle Hydrodynamics (SPH), we apply a set of discretization and smoothing rules to obtain a discrete action. Subsequent variations yield the Fat Particle equations. Our analysis of a classical ideal fluid demonstrated that a Newtonian Fat Particle is capable of remaining at rest while generating its own gravitational field. We then developed analogous principles for describing relativistic ideal fluids in both covariant and ADM 3+1 forms. Using these principles, we developed analytic and numerical results from relativistic Fat Particle theory. We began with the Subscribe Only model, in which a Fat Particle of negligible mass moves in a fixed background metric. Corrections to its motion due to the extended nature of the Fat Particle, are obtained by summing metric contributions over its volume. We find a universal scaling law that describes the phase shift, relative to a test particle, that is independent of its size, shape, and distribution. We then show that finite-size effects eventually dominate radiation damping effects in describing the motion of a white dwarf around a more

  4. Massive General Relativity: Theory and Applications

    NASA Astrophysics Data System (ADS)

    Gabadadze, Gregory

    The Universe, at very large scales, is expanding with acceleration. The fundamental reason for the accelerated expansion is not understood. One way to model such an expansion is to postulate a small cosmological constant in the Einstein equations. However, it could also be that Nature made a different choice: The acceleration could be a first observational evidence of a new scale at which laws of gravity itself are modified, and if so, the acceleration could have a purely gravitational origin. To account for the observed expansion, the new scale should roughly be equal to 1/H0 ~ 10^28 cm -- the present-day value of the Hubble length. Theories that may modify gravity consistently at these scales present a great challenge, and this has been a topic of an active research for the past decade or so. Furthermore, modified gravity models make predictions that could be distinguished from those of more conventional frameworks, e.g., from the scenario with a small cosmological constant. Moreover, the case for modified gravity is strengthened by a long-standing Cosmological Constant Problem (CCP). According to a well- known theorem, the CCP cannot be solved as long as one remains in a conventional framework of General Relativity (GR), or in other theory that reduces to GR at large scales. Contrary to this, theories that truly modify GR at large scales, can evade this theorem, and thus offer a hope for solving the CCP. The Principal Investigator (PI) is proposing to address the cosmic acceleration, and related to it CCP, in the framework of massive extension of GR. Construction of massive GR began as early as in 1939, however, for the last 40 years or so the theory was tabooed by no-go theorems. Only very recently, PI and his collaborators were able to show that there is a class of theories to which the no-go theorems do not apply, and proposed a candidate covariant theory for massive GR, that passes all the initial consistency tests. Moreover, PI with his collaborators found

  5. Unique Diagnostic of Magneto Optical Trap Relative Populations

    NASA Astrophysics Data System (ADS)

    Brédy, Richard; Nguyen, Hai; Camp, Howard A.; Wilson, Kyle M.; Awata, Takaaki; Depaola, Brett D.

    2003-05-01

    In the studies of population trapping, electromagnetically induced transparency, and other processes associated with coherent excitation, knowledge of excited state populations can provide greatly needed insights. However, methodologies often used to determine relative populations in laser-excited system often rely on a model-dependent measurement. Furthermore, lasers used to probe the system can modify the very system one wishes to make measurements on. An accurate, non-intrusive and perusing method has been developed to circumvent this problem. MOTRIMS (Magneto Optical Trap Recoil Ion Momentum Spectroscopy) uses charge transfer as a non-intrusive probe of temporal evolution of excited state fraction, in particular the 5p of Rb. The generalization of these measurements to more complicated systems, e.g. a Rubidium sample having mixture of 5s, 5p, 4d, and Rydberg states will be presented.

  6. The Concept of General Relativity is not Related to Reality

    NASA Astrophysics Data System (ADS)

    Kotas, Ronald

    2015-04-01

    The concept of general relativity is not related to reality. It is not real or factual Science. GR cannot account for objects falling to earth or for the weight of objects sitting on the earth. The Cavendish demonstration showing the attraction between two masses at right angles to earth's gravity, is not explained by GR. No one can prove the existence of ``space fabric.'' The concept of ``space time'' effects causing gravitational attraction between masses is wrong. Conservation law of energy - momentum does not exist in GR. LIGO fails in detecting ``gravity waves'' because there is no ``space fabric'' to transmit them. The Gravity B Probe data manipulated to show some effects, is not proof of ``space fabric.'' It is Nuclear Quantum Gravitation that provides clear definitive explanation of Gravity and Gravitation. It is harmonious with Newtonian and Quantum Mechanics, and Scientific Logic. Nuclear Quantum Gravitation has 10 clear, Scientific proofs and 21 more good indications. With this theory the Physical Forces are Unified. See: OBSCURANTISM ON EINSTEIN GRAVITATION? http://www.santilli-foundation.org/inconsistencies-gravitation.php and Einstein's Theory of Relativity versus Classical Mechanics, by Paul Marmet http://www.newtonphysics.on.ca/einstein/

  7. Gamma and Related Functions Generalized for Sequences

    ERIC Educational Resources Information Center

    Ollerton, R. L.

    2008-01-01

    Given a sequence g[subscript k] greater than 0, the "g-factorial" product [big product][superscript k] [subscript i=1] g[subscript i] is extended from integer k to real x by generalizing properties of the gamma function [Gamma](x). The Euler-Mascheroni constant [gamma] and the beta and zeta functions are also generalized. Specific examples include…

  8. Tardive and spontaneous dyskinesia incidence in the general population

    PubMed Central

    2013-01-01

    Background To identify the incidence rate of spontaneous dyskinesia (SD) and tardive dyskinesia (TD) in a general population and to examine the association between dykinesia and potential risk factors (exposure to metoclopramide [MCP], antipsychotic drugs, and history of diabetes and psychoses). Methods A retrospective cohort study was conducted for the years 2001 through 2010, based on medical claims data from the Deseret Mutual Benefit Administrators (DMBA). Results Thirty-four cases of TD and 229 cases of SD were identified. The incidence rate of TD among persons previously prescribed an antipsychotic or metoclopramide (MCP) (per 1,000) was 4.6 (1.6-7.7) for those with antipsychotic drug use only, 8.5 (4.8-12.2) for those with MCP use only, and 15.0 (2.0-28.1) for those with both antipsychotic and MCP use. In the general population, the incidence rate (per 100,000 person-years) of TD was 4.3 and of probable SD was 28.7. The incidence rates of TD and SD increased with age and were greater for females. Those with diabetes or psychoses had almost a 3-fold greater risk of TD than those without either of these diseases. Persons with schizophrenia had 31.2 times increased risk of TD than those without the disease. Positive associations also existed between the selected diseases and the incidence rate of probable SD, with persons with schizophrenia having 4.4 times greater risk of SD than those without the disease. Conclusions SD and TD are rare in this general population. Diabetes, psychoses, and especially schizophrenia are positively associated with SD and TD. A higher proportion of those with SD present with spasm of the eyelid muscles (blepharospasm) compared more with the TD cases who present more with orofacial muscular problems. PMID:23714238

  9. [Daytime consequences of insomnia complaints in the French general population].

    PubMed

    Ohayon, M M; Lemoine, P

    2004-01-01

    Insomnia is a frequent symptom in the general population; numerous studies have proven this. In the past years, classifications have gradually given more emphasis to daytime repercussions of insomnia and to their consequences on social and cognitive functioning. They are now integrated in the definition of insomnia and are used to quantify its severity. If the daytime consequences of insomnia are well known at the clinical level, there are few epidemiological data on this matter. The aim of this study was to assess the daytime repercussions of insomnia complaints in the general population of France. A representative sample (n=5,622) aged 15 or older was surveyed by telephone with the help of the sleep-EVAL expert system, a computer program specially designed to evaluate sleep disorders and to manage epidemiological investigations. Interviews have been completed for 80.8% of the solicited subjects (n=5,622). The variables considered comprised insomnia and its daytime repercussions on cognitive functioning, affective tone, daytime sleepiness and diurnal fatigue. Insomnia was found in 18.6% of the sample. The prevalence was higher in women (22.4%) than in men (14.5%, p<0.001) with a relative risk of 1.7 (95% confidence interval 1.5 to 2) and was twice more frequent for subjects 65 years of age or older compared to subjects younger than 45 years. Approximately 30% of subjects reporting insomnia had difficulties initiating sleep. Nearly 75% of insomnia complainers reported having a disrupted sleep or waking up too early in the morning and about 40% said they had a non-restorative sleep. Repercussions on daytime functioning were reported by most insomnia subjects (67%). Repercussions on cognitive functioning changed according age, number of insomnia symptoms and the use of a psychotropic medication. A decreased efficiency was more likely to be reported by subjects between 15 and 44 years of age (OR: 2.9), those using a psychotropic (OR: 1.5), those reporting at least

  10. High prevalence of celiac disease in Italian general population.

    PubMed

    Volta, U; Bellentani, S; Bianchi, F B; Brandi, G; De Franceschi, L; Miglioli, L; Granito, A; Balli, F; Tiribelli, C

    2001-07-01

    The worldwide increase of celiac disease prompted us to assess its prevalence in the Italian general population. The 3483 inhabitants of Campogalliano were tested for immunoglobulin A anti-endomysial antibodies. Twenty subjects showed antibody positivity and duodenal biopsy detected typical mucosal lesions of celiac disease in 17 of them; the remaining three cases had a normal villous architecture, but the finding of increased gamma/delta intraepithelial lymphocytes in all and the heterodimer DQA1*0501, DQB1*0201 in two of them was consistent with potential celiac disease. Only one patient had an overt malabsorption syndrome, characterized by diarrhea, weight loss, and severe weakness. In eight subjects atypical symptoms of celiac disease, such as dyspepsia and depression, were present, whereas the remaining subjects were silent. Celiac disease was more frequent in younger age groups. Our cross-sectional design study demonstrates that celiac disease prevalence in the Italian general population is 4.9 per 1000 (95% CI 2.8-7.8), increasing up to 5.7 per 1000 (95% CI 3.5-8.8) with the inclusion of potential cases. PMID:11478502

  11. General Population Norms about Child Abuse and Neglect and Associations with Childhood Experiences

    ERIC Educational Resources Information Center

    Bensley, L.; Ruggles, D.; Simmons, K.W.; Harris, C.; Williams, K.; Putvin, T.; Allen, M.

    2004-01-01

    Background:: A variety of definitions of child abuse and neglect exist. However, little is known about norms in the general population as to what constitutes child abuse and neglect or how perceived norms may be related to personal experiences. Methods:: We conducted a random-digit-dialed telephone survey of 504 Washington State adults.…

  12. Recruiting Gamblers from the General Population for Research Purposes: Outcomes from Two Contrasting Approaches

    ERIC Educational Resources Information Center

    Williams, Jeremy D.; Pulford, Justin; Bellringer, Maria; Abbott, Max

    2010-01-01

    Multiple means exist by which gamblers including problem gamblers may be recruited from the general population for research survey purposes. However, there appears to be limited discussion in the published literature about the relative merits of one or other approach. This paper addresses this gap, in part, by reporting the experiences of…

  13. Intimate Partner Violence in the U.S. General Population: Progress and Future Directions

    ERIC Educational Resources Information Center

    Field, Craig A.; Caetano, Raul

    2005-01-01

    This article reviews survey research on intimate partner violence (IPV) in the U.S. general population. Results from survey research conducted over the past quarter century are briefly summarized. Three additional national studies related to injuries, crime victimization, and homicide among intimate partners in the United States are also…

  14. Prevalence of Chronic Medical Conditions in Adults with Mental Retardation: Comparison with the General Population.

    ERIC Educational Resources Information Center

    Kapell, Deborah; Nightingale, Beryle; Rodriguez, Ana; Lee, Joseph H.; Zigman, Warren B.; Schupf, Nicole

    1998-01-01

    A study interviewed caregivers and reviewed medical records of 278 adults with mental retardation with and without Down syndrome. The adults with mental retardation had age-related disorders comparable to those in the general population, but there was an increased frequency of thyroid disorders, nonischemic heart disorders, and sensory impairment.…

  15. 29 CFR 778.5 - Relation to other laws generally.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Relation to other laws generally. 778.5 Section 778.5 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS OVERTIME COMPENSATION General Considerations § 778.5 Relation to other...

  16. Anti-HCV prevalence in the general population of Lithuania

    PubMed Central

    Liakina, Valentina; Valantinas, Jonas

    2012-01-01

    Summary Background The aim of this study was to assess risk factors for HCV acquisition and prevalence of anti-HCV in the general population of Lithuania. Material/Methods The study enrolled 1528 randomly selected adults from the 5 biggest cities of Lithuania and its rural regions. Screening for anti-HCV was performed by analysis of peripheral capillary blood with lateral flow immunochromatography and confirmation of positive cases by peripheral venous blood testing with 2-step chemiluminescent microparticle immunoassay. Results Anti-HCV prevalence in Lithuania is 2.78% and according to the standard European population the adjusted anti-HCV rate is 2.85%. It is more prevalent among men (crude rates: 4.02% males vs. 1.49% females, p=.0030) and this does not depend on age. Vilnius and Kaunas regions have higher infection rates than smaller rural regions (2.92% and 3.01% vs. 2.24%, 0.74% and 1.35%). Nowadays among our population HCV infection spreads mainly via intravenous drug use (OR=42.5, p<.0001). HCV transmission occurs through blood transfusions (OR=6.4, p=.0002), tooth removal (OR=4.1, p=.0048), childbirth (OR=5.0, p=.0224), multiple and a long-term hospitalization (OR=3.0, p=.0064), tattooing (OR=4.4, p=.0013), open traumas (OR=3.7, p=.0009) and intrafamilially (OR=11.3, p=.0002). Conclusions 2.78% of the population is anti-HCV-positive. The anti-HCV rate is higher in Vilnius and Kaunas in comparison with other regions. HCV spreads mainly through intravenous drug use, but intrafamilial and some nosocomial routes are also important. The anti-HCV prevalence did not depend on age. Despite active prevention of nosocomial HCV transmission, the incidence of HCV infection does not decrease due to virus spread mostly in “trusted networks” of intravenous drug users. PMID:22367136

  17. An Elementary Formalism for General Relativity.

    ERIC Educational Resources Information Center

    diSessa, Andrea A.

    1981-01-01

    An elementary formalism is developed for representing curved space-time which allows transparent qualitative explanation of general relativistic effects and is used to make a conceptual analysis of Einstein's principle of equivalence. A final section outlines a number of student activities. (Author/SK)

  18. The value of a college degree for foster care alumni: comparisons with general population samples.

    PubMed

    Salazar, Amy M

    2013-04-01

    Higher education is associated with substantial adult life benefits, including higher income and improved quality of life, among others. The current study compared adult outcomes of 250 foster care alumni college graduates with two samples of general population graduates to explore the role higher education plays in these young adults' lives. Outcomes compared include employment, income, housing, public assistance, physical and mental health, happiness, and other outcomes that are often found to be related to educational attainment. Foster care alumni college graduates were very similar to general population college graduates for individual income and rate of employment. However, foster care alumni graduates were behind general population graduates on factors such as self-reported job security, household earnings, health, mental health, financial satisfaction, home ownership, happiness, and public assistance usage. Results have implications for policy and practice regarding the most effective means of supporting postcollege stability of youths with foster care experience. PMID:23724577

  19. The value of a college degree for foster care alumni: comparisons with general population samples.

    PubMed

    Salazar, Amy M

    2013-04-01

    Higher education is associated with substantial adult life benefits, including higher income and improved quality of life, among others. The current study compared adult outcomes of 250 foster care alumni college graduates with two samples of general population graduates to explore the role higher education plays in these young adults' lives. Outcomes compared include employment, income, housing, public assistance, physical and mental health, happiness, and other outcomes that are often found to be related to educational attainment. Foster care alumni college graduates were very similar to general population college graduates for individual income and rate of employment. However, foster care alumni graduates were behind general population graduates on factors such as self-reported job security, household earnings, health, mental health, financial satisfaction, home ownership, happiness, and public assistance usage. Results have implications for policy and practice regarding the most effective means of supporting postcollege stability of youths with foster care experience.

  20. A General Paradigm for Public Relations Research.

    ERIC Educational Resources Information Center

    Whitcomb, Debra

    Grunig's decision-situation model is proposed as a comprehensive framework under which various public-relations-related theories may be subsumed. The decision-situation model postulates three dimensions which, taken together, may predict the course of communication behavior: level of involvement, problem recognition, and structural constraints.…

  1. Generating matter inhomogeneities in general relativity.

    PubMed

    Coley, A A; Lim, W C

    2012-05-11

    In this Letter we discuss a natural general relativistic mechanism that causes inhomogeneities and hence generates matter perturbations in the early Universe. We concentrate on spikes, both incomplete spikes and recurring spikes, that naturally occur in the initial oscillatory regime of general cosmological models. In particular, we explicitly show that spikes occurring in a class of G2 models lead to inhomogeneities that, due to gravitational instability, leave small residual imprints on matter in the form of matter perturbations. The residual matter overdensities from recurring spikes are not local but form on surfaces. We discuss the potential physical consequences of the residual matter imprints and their possible effect on the subsequent formation of large-scale structure.

  2. Testing general relativity using a bouncing ball

    NASA Astrophysics Data System (ADS)

    Liang, Shiuan-Ni; Lan, Boon Leong

    In a recent article (Liang and Lan, (2011)), we showed that the trajectories predicted by general-relativistic and Newtonian mechanics from the same parameters and initial conditions for a low-speed weak-gravity bouncing ball system will rapidly disagree completely if the trajectories are chaotic. Here, we determine how accurate the parameters and initial conditions of the system must be known so that the two different calculated chaotic trajectories are sufficiently accurate for an empirical test.

  3. Prevalence of Titin Truncating Variants in General Population

    PubMed Central

    Akinrinade, Oyediran; Koskenvuo, Juha W.; Alastalo, Tero-Pekka

    2015-01-01

    Background Truncating titin (TTN) mutations, especially in A-band region, represent the most common cause of dilated cardiomyopathy (DCM). Clinical interpretation of these variants can be challenging, as these variants are also present in reference populations. We carried out systematic analyses of TTN truncating variants (TTNtv) in publicly available reference populations, including, for the first time, data from Exome Aggregation Consortium (ExAC). The goal was to establish more accurate estimate of prevalence of different TTNtv to allow better clinical interpretation of these findings. Methods and Results Using data from 1000 Genomes Project, Exome Sequencing Project (ESP) and ExAC, we estimated the prevalence of TTNtv in the population. In the three population datasets, 52–54% of TTNtv were not affecting all TTN transcripts. The frequency of truncations affecting all transcripts in ExAC was 0.36% (0.32% - 0.41%, 95% CI) and 0.19% (0.16% - 0.23%, 95% CI) for those affecting the A-band. In the A-band region, the prevalences of frameshift, nonsense and essential splice site variants were 0.057%, 0.090%, and 0.047% respectively. Cga/Tga (arginine/nonsense–R/*) transitional change at CpG mutation hotspots was the most frequent type of TTN nonsense mutation accounting for 91.3% (21/23) of arginine residue nonsense mutation (R/*) at TTN A-band region. Non-essential splice-site variants had significantly lower proportion of private variants and higher proportion of low-frequency variants compared to essential splice-site variants (P = 0.01; P = 5.1 X 10−4, respectively). Conclusion A-band TTNtv are more rare in the general population than previously reported. Based on this analysis, one in 500 carries a truncation in TTN A-band suggesting the penetrance of these potentially harmful variants is still poorly understood, and some of these variants do not manifest as autosomal dominant DCM. This calls for caution when interpreting TTNtv in individuals and families

  4. General Allee effect in two-species population biology.

    PubMed

    Livadiotis, G; Elaydi, S

    2012-01-01

    The main objective of this work is to present a general framework for the notion of the strong Allee effect in population models, including competition, mutualistic, and predator-prey models. The study is restricted to the strong Allee effect caused by an inter-specific interaction. The main feature of the strong Allee effect is that the extinction equilibrium is an attractor. We show how a 'phase space core' of three or four equilibria is sufficient to describe the essential dynamics of the interaction between two species that are prone to the Allee effect. We will introduce the notion of semistability in planar systems. Finally, we show how the presence of semistable equilibria increases the number of possible Allee effect cores.

  5. Transvestic fetishism in the general population: prevalence and correlates.

    PubMed

    Långström, Niklas; Zucker, Kenneth J

    2005-01-01

    We used a random sample of 2,450 18-60 year-olds in the general population of Sweden to study the prevalence as well as the social, sexual, and health correlates of transvestic fetishism (sexual arousal from cross-dressing). Almost three percent (2.8%) of men and 0.4% of women reported at least one episode of transvestic fetishism. Separation from parents, same-sex sexual experiences, being easily sexually aroused, pornography use, and higher masturbation frequency were significantly associated with transvestic fetishism. A positive attitude to this sexual practice and paraphilia indicators--sexual arousal from using pain, exposing genitals to a stranger, and spying on others having sex--were particularly strong correlates to the dependent variable. PMID:15859369

  6. Polypharmacy in older adults with human immunodeficiency virus infection compared with the general population

    PubMed Central

    Gimeno-Gracia, Mercedes; Crusells-Canales, María José; Armesto-Gómez, Francisco Javier; Compaired-Turlán, Vicente; Rabanaque-Hernández, María José

    2016-01-01

    Background The percentage of older HIV-positive patients is growing, with an increase in age-related comorbidities and concomitant medication. Objectives To quantify polypharmacy and profile types of non-antiretroviral drugs collected at community pharmacies in 2014 by HIV-positive individuals on antiretroviral therapy and to compare these findings with those of the general population. Methods HIV-positive patients (n=199) were compared with a group of patients from the general population (n=8,172), aged between 50 and 64 years. The factors compared were prevalence of polypharmacy (≥5 comedications with cumulative defined daily dose [DDD] per drug over 180), percentage of patients who collected each therapeutic class of drug, and median duration for each drug class (based on DDD). Results were stratified by sex. Results Polypharmacy was more common in HIV-positive males than in the male general population (8.9% vs 4.4%, P=0.010). Polypharmacy was also higher in HIV-positive females than in the female general population (11.3% vs 3.4%, P=0.002). Percentage of HIV-positive patients receiving analgesics, anti-infectives, gastrointestinal drugs, central nervous system (CNS) agents, and respiratory drugs was higher than in the general population, with significant differences between male populations. No differences were observed in proportion of patients receiving cardiovascular drugs. The estimated number of treatment days (median DDDs) were higher in HIV-positive males than in males from the general population for anti-infectives (32.2 vs 20.0, P<0.001) and CNS agents (238.7 vs 120.0, P=0.002). A higher percentage of HIV-positive males than males from the general population received sulfonamides (17.1% vs 1.5%, P<0.001), macrolides (37.1% vs 24.9%, P=0.020), and quinolones (34.3% vs 21.2%, P=0.009). Conclusion Polypharmacy is more common in HIV-positive older males and females than in similarly aged members of the general population. HIV-positive patients received

  7. Polypharmacy in older adults with human immunodeficiency virus infection compared with the general population

    PubMed Central

    Gimeno-Gracia, Mercedes; Crusells-Canales, María José; Armesto-Gómez, Francisco Javier; Compaired-Turlán, Vicente; Rabanaque-Hernández, María José

    2016-01-01

    Background The percentage of older HIV-positive patients is growing, with an increase in age-related comorbidities and concomitant medication. Objectives To quantify polypharmacy and profile types of non-antiretroviral drugs collected at community pharmacies in 2014 by HIV-positive individuals on antiretroviral therapy and to compare these findings with those of the general population. Methods HIV-positive patients (n=199) were compared with a group of patients from the general population (n=8,172), aged between 50 and 64 years. The factors compared were prevalence of polypharmacy (≥5 comedications with cumulative defined daily dose [DDD] per drug over 180), percentage of patients who collected each therapeutic class of drug, and median duration for each drug class (based on DDD). Results were stratified by sex. Results Polypharmacy was more common in HIV-positive males than in the male general population (8.9% vs 4.4%, P=0.010). Polypharmacy was also higher in HIV-positive females than in the female general population (11.3% vs 3.4%, P=0.002). Percentage of HIV-positive patients receiving analgesics, anti-infectives, gastrointestinal drugs, central nervous system (CNS) agents, and respiratory drugs was higher than in the general population, with significant differences between male populations. No differences were observed in proportion of patients receiving cardiovascular drugs. The estimated number of treatment days (median DDDs) were higher in HIV-positive males than in males from the general population for anti-infectives (32.2 vs 20.0, P<0.001) and CNS agents (238.7 vs 120.0, P=0.002). A higher percentage of HIV-positive males than males from the general population received sulfonamides (17.1% vs 1.5%, P<0.001), macrolides (37.1% vs 24.9%, P=0.020), and quinolones (34.3% vs 21.2%, P=0.009). Conclusion Polypharmacy is more common in HIV-positive older males and females than in similarly aged members of the general population. HIV-positive patients received

  8. The dystrophin gene and cognitive function in the general population

    PubMed Central

    Vojinovic, Dina; Adams, Hieab HH; van der Lee, Sven J; Ibrahim-Verbaas, Carla A; Brouwer, Rutger; van den Hout, Mirjam CGN; Oole, Edwin; van Rooij, Jeroen; Uitterlinden, Andre; Hofman, Albert; van IJcken, Wilfred FJ; Aartsma-Rus, Annemieke; van Ommen, GertJan B; Ikram, M Arfan; van Duijn, Cornelia M; Amin, Najaf

    2015-01-01

    The aim of our study is to investigate whether single-nucleotide dystrophin gene (DMD) variants associate with variability in cognitive functions in healthy populations. The study included 1240 participants from the Erasmus Rucphen family (ERF) study and 1464 individuals from the Rotterdam Study (RS). The participants whose exomes were sequenced and who were assessed for various cognitive traits were included in the analysis. To determine the association between DMD variants and cognitive ability, linear (mixed) modeling with adjustment for age, sex and education was used. Moreover, Sequence Kernel Association Test (SKAT) was used to test the overall association of the rare genetic variants present in the DMD with cognitive traits. Although no DMD variant surpassed the prespecified significance threshold (P<1 × 10−4), rs147546024:A>G showed strong association (β=1.786, P-value=2.56 × 10−4) with block-design test in the ERF study, while another variant rs1800273:G>A showed suggestive association (β=−0.465, P-value=0.002) with Mini-Mental State Examination test in the RS. Both variants are highly conserved, although rs147546024:A>G is an intronic variant, whereas rs1800273:G>A is a missense variant in the DMD which has a predicted damaging effect on the protein. Further gene-based analysis of DMD revealed suggestive association (P-values=0.087 and 0.074) with general cognitive ability in both cohorts. In conclusion, both single variant and gene-based analyses suggest the existence of variants in the DMD which may affect cognitive functioning in the general populations. PMID:25227141

  9. Theory of mind and hypomanic traits in general population.

    PubMed

    Terrien, Sarah; Stefaniak, Nicolas; Blondel, Marine; Mouras, Harold; Morvan, Yannick; Besche-Richard, Chrystel

    2014-03-30

    Theory of Mind (ToM) is the ability to assign a set of mental states to yourself and others. In bipolar disorders, alteration of social relationship can be explained by the impairment of the functioning of ToM. Deficit in ToM could be a trait marker of bipolar disorder and people in the general population with high hypomanic personality scores would be more likely to develop bipolar disorders. This study examined 298 participants. Measures of hypomanic personality were evaluated using the Hypomanic Personality Scale. ToM was explored using the Yoni task. Participants also completed the BDI-II. Forward multiple regressions were performed to examine the effect of components of the HPS on the total score in the ToM task. In the women's group, no subscales of the HPS were included in the model. Conversely, the analyses performed on men revealed that the mood vitality and excitement subscale was a significant predictor of ToM abilities. Our study is the first to show the impact of certain dimensions of hypomanic personality on performance in ToM in a male sample. This result supports the idea that deficits in ToM can be a trait marker of bipolar disorder in a healthy male population.

  10. Theory of mind and hypomanic traits in general population.

    PubMed

    Terrien, Sarah; Stefaniak, Nicolas; Blondel, Marine; Mouras, Harold; Morvan, Yannick; Besche-Richard, Chrystel

    2014-03-30

    Theory of Mind (ToM) is the ability to assign a set of mental states to yourself and others. In bipolar disorders, alteration of social relationship can be explained by the impairment of the functioning of ToM. Deficit in ToM could be a trait marker of bipolar disorder and people in the general population with high hypomanic personality scores would be more likely to develop bipolar disorders. This study examined 298 participants. Measures of hypomanic personality were evaluated using the Hypomanic Personality Scale. ToM was explored using the Yoni task. Participants also completed the BDI-II. Forward multiple regressions were performed to examine the effect of components of the HPS on the total score in the ToM task. In the women's group, no subscales of the HPS were included in the model. Conversely, the analyses performed on men revealed that the mood vitality and excitement subscale was a significant predictor of ToM abilities. Our study is the first to show the impact of certain dimensions of hypomanic personality on performance in ToM in a male sample. This result supports the idea that deficits in ToM can be a trait marker of bipolar disorder in a healthy male population. PMID:24445165

  11. Latex allergy: a relevant issue in the general pediatric population.

    PubMed

    Lee, M H; Kim, K T

    1998-01-01

    Although latex allergy is a widely recognized problem of the pediatric myelomeningocele population and of frequent users of latex products, it is often overlooked in the general pediatric population. The prevalence of latex in common household items and in medical environments increases one's exposure and thus one's possibility of sensitization to latex. Latex allergy may range from mild local reactions such as erythema to more severe systemic reactions such as asthma or anaphylaxis. The immunoglobulin E-mediated mechanism of these reactions has been confirmed serologically by the presence of latex-specific immunoglobulin E with radioallergosorbent testing. Because avoidance of latex is currently the only way to prevent reactions, the identification of household items that contain latex is extremely important. However, because inadvertent exposure to latex is not uncommon, Medic-Alert bracelets and an Epi-Pen should be provided for children allergic to latex. Pediatric nurses should consider latex allergy as a possible diagnosis in situations of unexplained allergic or anaphylactic reactions and should be aware of optimal therapeutic interventions. PMID:9987254

  12. Grand Canonical Ensembles in General Relativity

    NASA Astrophysics Data System (ADS)

    Klein, David; Yang, Wei-Shih

    2012-03-01

    We develop a formalism for general relativistic, grand canonical ensembles in space-times with timelike Killing fields. Using that, we derive ideal gas laws, and show how they depend on the geometry of the particular space-times. A systematic method for calculating Newtonian limits is given for a class of these space-times, which is illustrated for Kerr space-time. In addition, we prove uniqueness of the infinite volume Gibbs measure, and absence of phase transitions for a class of interaction potentials in anti-de Sitter space.

  13. Exposure of Prague's homeless population to lead and cadmium, compared to Prague's general population.

    PubMed

    Hrncírová, Dana; Batáriová, Andrea; Cerná, Milena; Procházka, Bohumír; Dlouhý, Pavel; Andel, Michal

    2008-10-01

    Homelessness is a growing problem in the Czech Republic where homeless people represent a specific minority group beset by many problems linked to their divergent lifestyle. It was therefore expected that the homeless population would be at greater risk of exposure to environmental pollutants than the general population. The aim of our study was to compare blood lead (B-Pb) and blood cadmium (B-Cd) levels in the homeless population (HP) with those obtained from the Human Biomonitoring Project (CZ-HBM), which used blood donors considered representative of the general population (GP). We present data obtained between 2004 and 2006 for B-Pb and B-Cd in 257 Prague homeless adults and compare them to B-Pb and B-Cd levels in 104 Prague adult blood donors from the CZ-HBM project in 2005. The mean (geometric) B-Pb levels in men were 36.5 (HP) and 35.4microg/l (GP), which is not significantly different. However, statistically significant differences were observed between men and women in the GP (P<0.001), but not in HP; B-Pb levels in women (34.8microg/l) did not differ from those of HP men (36.5microg/l), but were significantly (P<0.001) higher than those of GP women (25.8microg/l). B-Pb levels were not influenced by smoking. B-Cd levels in the homeless nonsmokers (geometric means 1.06 and 1.18microg/l in men and women, respectively) were more than 2.5 times higher than in the nonsmoking GP (0.36 and 0.38microg/l for men and women, respectively). B-Cd levels were significantly (P<0.001) influenced by smoking in both groups, but, surprisingly, the values in GP smokers (men=0.96microg/l, women=0.93microg/l) were lower than those in HP nonsmokers (men=1.06microg/l, women=1.18microg/l). A positive correlation was found between cadmium and lead in both men (P<0.05) and women (P<0.01). Our results indicate that the homeless population under study might be exposed to lead and cadmium more extensively than the general population of Prague and that homeless women represent a

  14. Enterobius vermicularis infection among population of General Mansilla, Argentina

    PubMed Central

    Pezzani, Betina C; Minvielle, Marta C; de Luca, María M; Córdoba, María A; Apezteguía, María C; Basualdo, Juan A

    2004-01-01

    AIM: To evaluate the relationships between the personal, sociocultural, and environmental characteristics, and the presence or absence of symptoms with the detection of Enterobius vermicularis (E. vermicularis) in a population sample in our region (General Mansilla, Province of Buenos Aires, Argentina), by individual and familiar analyses. METHODS: E. vermicularis was diagnosed in 309 people from 70 family units residing in the urban area and the rural area of the city of General Mansilla. Each of them was surveyed so as to register personal, environmental and sociocultural data. Questions about the presence or absence of anal itch, abdominal pain and sleeping disorder were also asked. Significant associations were determined by square chi tests. Logistic regression models were adjusted by using a backward conditional stepwise method to determine the presence of this parasite in the individuals and in the families. RESULTS: The parasites were found in 29.12% (90/309) of the individuals, with a frequency of 14.28% (20/140) among the heads of the families and of 41.42% (70/169) among the children. The only variables showing a significant association were affiliation, where the risk category was "being the son/daughter of", and the symptoms were abdominal pain, sleeping disorder, and anal itch. Families with a member infected with parasite were considered Positive Families (PF) and they were 40/70 (57.14%), only 5% (2/40) of the PF had 100% of their members infected with the parasite. The logistic regression models applied showed that the risk categories were mainly affiliation (son/daughter) and housing (satisfactory) among others. CONCLUSION: The presence of E. vermicularis was proved in one third of the studied population. The frequency of families with all their members infected with the parasite was very low. Most of the studied personal, sociocultural, and environmental variables did not turn out to be significantly associated with the presence of the parasite

  15. Uncertainty relations for general phase spaces

    NASA Astrophysics Data System (ADS)

    Werner, Reinhard F.

    2016-04-01

    We describe a setup for obtaining uncertainty relations for arbitrary pairs of observables related by a Fourier transform. The physical examples discussed here are the standard position and momentum, number and angle, finite qudit systems, and strings of qubits for quantum information applications. The uncertainty relations allow for an arbitrary choice of metric for the outcome distance, and the choice of an exponent distinguishing, e.g., absolute and root mean square deviations. The emphasis of this article is on developing a unified treatment, in which one observable takes on values in an arbitrary locally compact Abelian group and the other in the dual group. In all cases, the phase space symmetry implies the equality of measurement and preparation uncertainty bounds. There is also a straightforward method for determining the optimal bounds.

  16. Work-related asthma and implications for the general public.

    PubMed Central

    Petsonk, Edward L

    2002-01-01

    Asthma has been increasing over the last two decades in the United States. The onset of asthma has also been increasingly reported as a result of occupational exposures to over 350 different agents. Work-related asthma (WRA) has become the most frequently diagnosed occupational respiratory illness. Epidemiologic studies from the United States reported WRA incidence rates of 29-710 cases per million workers per year and suggest that 10-25% of adult asthma is work related. Much can be learned about asthma in the general population from investigations of asthma in the workplace. Surveillance of WRA continues to highlight an important role for low molecular weight chemical sensitizers, as well as high molecular weight antigens. Additionally, recent reports implicate mixed exposures, including commercial cleaning solutions, solvents, and other respiratory irritants, as well as contamination in nonindustrial environments, including schools and offices. Investigations of WRA have demonstrated a clear dose-related increase in sensitization and symptoms for exposures to both chemical and protein sensitizers. High proportions of exposed working groups can be affected. Skin exposures may affect the likelihood of individuals developing respiratory symptoms. Atopy increases the risk of sensitization and illness from workplace exposure to antigens but not to chemical sensitizers. Irritant exposures can act as adjuvants among individuals exposed to sensitizing substances, increasing the proportion who become sensitized. Atopy might also be a result of irritant exposures in some persons. Occupational asthma often has important long-term adverse health and economic consequences but can resolve completely with timely control of exposures. Detailed study of such asthma "cures" may prove useful in understanding factors that influence asthmatic airway inflammation in the general population. PMID:12194889

  17. Connection between Newtonian simulations and general relativity

    SciTech Connect

    Chisari, Nora Elisa; Zaldarriaga, Matias

    2011-06-15

    On large scales, comparable to the horizon, the observable clustering properties of galaxies are affected by various general relativistic effects. To calculate these effects one needs to consistently solve for the metric, densities, and velocities in a specific coordinate system or gauge. The method of choice for simulating large-scale structure is numerical N-body simulations which are performed in the Newtonian limit. Even though one might worry that the use of the Newtonian approximation would make it impossible to use these simulations to compute properties on very large scales, we show that the simulations are still solving the dynamics correctly even for long modes and we give formulas to obtain the position of particles in the conformal Newtonian gauge given the positions computed in the simulation. We also give formulas to convert from the output coordinates of N-body simulations to the observable coordinates of the particles.

  18. Life Expectancy in Police Officers: A Comparison with the U.S. General Population

    PubMed Central

    Violanti, John M.; Hartley, Tara A.; Gu, Ja K.; Fekedulegn, Desta; Andrew, Michael E.; Burchfiel, Cecil M.

    2016-01-01

    Previous epidemiological research indicates that police officers have an elevated risk of death relative to the general population overall and for several specific causes. Despite the increased risk for mortality found in previous research, controversy still exists over the life expectancy of police officers. The goal of the present study was to compare life expectancy of male police officers from Buffalo New York with the U.S. general male population utilizing an abridged life table method. On average, the life expectancy of Buffalo police officers in our sample was significantly lower than the U.S. population (mean difference in life expectancy =21.9 years; 95% CI: 14.5-29.3; p<0.0001). Life expectancy of police officers was shorter and differences were more pronounced in younger age categories. Additionally, police officers had a significantly higher average probability of death than did males in the general population (mean difference= 0.40; 95% CI: 0.26,-0.54; p<0.0001). The years of potential life lost (YPLL) for police officers was 21 times larger than that of the general population (Buffalo male officers vs. U.S. males = 21.7, 95% CI: 5.8-37.7). Possible reasons for shorter life expectancy among police are discussed, including stress, shift work, obesity, and hazardous environmental work exposures. PMID:24707585

  19. BOOK REVIEW: Advanced Mechanics and General Relativity Advanced Mechanics and General Relativity

    NASA Astrophysics Data System (ADS)

    Louko, Jorma

    2011-04-01

    Joel Franklin's textbook `Advanced Mechanics and General Relativity' comprises two partially overlapping, partially complementary introductory paths into general relativity at advanced undergraduate level. Path I starts with the Lagrangian and Hamiltonian formulations of Newtonian point particle motion, emphasising the action principle and the connection between symmetries and conservation laws. The concepts are then adapted to point particle motion in Minkowski space, introducing Lorentz transformations as symmetries of the action. There follows a focused development of tensor calculus, parallel transport and curvature, using examples from Newtonian mechanics and special relativity, culminating in the field equations of general relativity. The Schwarzschild solution is analysed, including a detailed discussion of the tidal forces on a radially infalling observer. Basics of gravitational radiation are examined, highlighting the similarities to and differences from electromagnetic radiation. The final topics in Path I are equatorial geodesics in Kerr and the motion of a relativistic string in Minkowski space. Path II starts by introducing scalar field theory on Minkowski space as a limit of point masses connected by springs, emphasising the action principle, conservation laws and the energy-momentum tensor. The action principle for electromagnetism is introduced, and the coupling of electromagnetism to a complex scalar field is developed in a detailed and pedagogical fashion. A free symmetric second-rank tensor field on Minkowski space is introduced, and the action principle of general relativity is recovered from coupling the second-rank tensor to its own energy-momentum tensor. Path II then merges with Path I and, supplanted with judicious early selections from Path I, can proceed to the Schwarzschild solution. The choice of material in each path is logical and focused. A notable example in Path I is that Lorentz transformations in Minkowki space are introduced

  20. Action principle combining electromagnetism and general relativity

    SciTech Connect

    Moyer, H.G.

    1987-03-01

    The stationary action problem for a single, classical, point particle in external gravitational and electromagnetic fields is written in optimal control format. The relativistic interval is the independent variable and time, space, and action are the five dependent variables. A general metric is used for the space-time manifold so that the equations are manifestly covariant. The form of the system equations guarantees that the particle moves with unit speed with respect to interval. The Lagrangian is a function of the metric tensor and the electromagnetic four-potential, but not of particle parameters such as electric charge q and mass m. The Hamiltonian is not identically zero, unlike those derived in many earlier analyses. A constant of the motion is found that is identified with q/mc/sup 2/. An explanation is presented for the classical inequality mgreater than or equal to0. The trajectories can reduce to geodesics and even further to those governed by Fermat's principle of stationary time.

  1. Towards absorbing outer boundaries in general relativity

    NASA Astrophysics Data System (ADS)

    Buchman, Luisa T.; Sarbach, Olivier C. A.

    2006-12-01

    We construct exact solutions to the Bianchi equations on a flat spacetime background. When the constraints are satisfied, these solutions represent in- and outgoing linearized gravitational radiation. We then consider the Bianchi equations on a subset of flat spacetime of the form [0, T] × BR, where BR is a ball of radius R, and analyse different kinds of boundary conditions on ∂BR. Our main results are as follows. (i) We give an explicit analytic example showing that boundary conditions obtained from freezing the incoming characteristic fields to their initial values are not compatible with the constraints. (ii) With the help of the exact solutions constructed, we determine the amount of artificial reflection of gravitational radiation from constraint-preserving boundary conditions which freeze the Weyl scalar Ψ0 to its initial value. For monochromatic radiation with wave number k and arbitrary angular momentum number ell >= 2, the amount of reflection decays as (kR)-4 for large kR. (iii) For each L >= 2, we construct new local constraint-preserving boundary conditions which perfectly absorb linearized radiation with ell <= L. (iv) We generalize our analysis to a weakly curved background of mass M and compute first-order corrections in M/R to the reflection coefficients for quadrupolar odd-parity radiation. For our new boundary condition with L = 2, the reflection coefficient is smaller than that for the freezing Ψ0 boundary condition by a factor of M/R for kR > 1.04. Implications of these results for numerical simulations of binary black holes on finite domains are discussed.

  2. Does probability of occurrence relate to population dynamics?

    PubMed Central

    Thuiller, Wilfried; Münkemüller, Tamara; Schiffers, Katja H.; Georges, Damien; Dullinger, Stefan; Eckhart, Vincent M.; Edwards, Thomas C.; Gravel, Dominique; Kunstler, Georges; Merow, Cory; Moore, Kara; Piedallu, Christian; Vissault, Steve; Zimmermann, Niklaus E.; Zurell, Damaris; Schurr, Frank M.

    2014-01-01

    Hutchinson defined species’ realized niche as the set of environmental conditions in which populations can persist in the presence of competitors. In terms of demography, the realized niche corresponds to the environments where the intrinsic growth rate (r) of populations is positive. Observed species occurrences should reflect the realized niche when additional processes like dispersal and local extinction lags do not have overwhelming effects. Despite the foundational nature of these ideas, quantitative assessments of the relationship between range-wide demographic performance and occurrence probability have not been made. This assessment is needed both to improve our conceptual understanding of species’ niches and ranges and to develop reliable mechanistic models of species geographic distributions that incorporate demography and species interactions. The objective of this study is to analyse how demographic parameters (intrinsic growth rate r and carrying capacity K) and population density (N) relate to occurrence probability (Pocc). We hypothesized that these relationships vary with species’ competitive ability. Demographic parameters, density, and occurrence probability were estimated for 108 tree species from four temperate forest inventory surveys (Québec, Western US, France and Switzerland). We used published information of shade tolerance as indicators of light competition strategy, assuming that high tolerance denotes high competitive capacity in stable forest environments. Interestingly, relationships between demographic parameters and occurrence probability did not vary substantially across degrees of shade tolerance and regions. Although they were influenced by the uncertainty in the estimation of the demographic parameters, we found that r was generally negatively correlated with Pocc, while N, and for most regions K, was generally positively correlated with Pocc. Thus, in temperate forest trees the regions of highest occurrence probability

  3. Gastroesophageal reflux disease symptoms in the Greek general population: prevalence and risk factors

    PubMed Central

    Spantideas, Nikolaos; Drosou, Eirini; Bougea, Anastasia; Assimakopoulos, Dimitrios

    2016-01-01

    Background and aims Population-based data regarding the prevalence of gastroesophageal reflux disease (GERD) in Greece are very poor. This study estimated the prevalence of GERD symptoms and their risk factors in the Greek adult population. Methods A self-administered questionnaire was answered by a randomly selected population of 340 subjects. The question regarding “heartburn, chest pain, indigestion, or stomach acid coming up” as included in the Reflux Symptom Index was used for prevalence assessment. Results The monthly prevalence of GERD symptoms was found to be 52.0% in the Greek general population, with no statistically significant difference between the two sexes (P>0.05). The age group of 65–79 years showed a higher prevalence rate of GERD. Symptom severity was found to be mild (59.3%) or moderate (27.1%). The number of cigarettes smoked daily (but not smoking duration) as well as the number of alcoholic drinks consumed daily (but not the duration of alcohol drinking) were found to be related to GERD symptoms. No reported concomitant disease or medication was found to be related with GERD symptoms. Conclusion The prevalence of GERD symptoms in the Greek general population was found to be 52.0%. Tobacco smoking and alcohol drinking but not concomitant disease or medications were found to be related with GERD symptoms. PMID:27382324

  4. [Schizotypy and verbal memory in the adolescent general population].

    PubMed

    Martinena Palacio, Patricia; Navarro, J Blas; Medina Pradas, Cristina; Baños Yeste, Iris; Sabanés, Arantxa; Vicens Vilanova, Jordi; Alvarez, Eva M; Barrantes Vidal, Neus; Subirá, Susana; Obiols, Jordi E

    2006-08-01

    The following study examines the relationship between verbal memory deficits and schizotypal traits measured psychometrically from a non- clinical adolescent population. In this transversal analytical study participated 139 subjects. They were secondary school students, with ages ranging from 13 to 16 years old (mean= 14, 35; Sta.Dev.= 0, 548). After administrating the scales O-LIFE (psychometrical schizotypy), CVLT (verbal memory), and Letters and Numbers subtest of WAIS-III (working memory), data was analyzed utilizing Pearson correlations and mean comparison test. Results showed lack of relations between schizotypy measures and working memory. Nonetheless, some of the O-LIFE dimensions correlated with verbal memory. These findings support partly the literature reviewed. Yet, more work focused on schizotypy and cognitive deficits as risk factors are suggested.

  5. BOOK REVIEW: Advanced Mechanics and General Relativity Advanced Mechanics and General Relativity

    NASA Astrophysics Data System (ADS)

    Louko, Jorma

    2011-04-01

    Joel Franklin's textbook `Advanced Mechanics and General Relativity' comprises two partially overlapping, partially complementary introductory paths into general relativity at advanced undergraduate level. Path I starts with the Lagrangian and Hamiltonian formulations of Newtonian point particle motion, emphasising the action principle and the connection between symmetries and conservation laws. The concepts are then adapted to point particle motion in Minkowski space, introducing Lorentz transformations as symmetries of the action. There follows a focused development of tensor calculus, parallel transport and curvature, using examples from Newtonian mechanics and special relativity, culminating in the field equations of general relativity. The Schwarzschild solution is analysed, including a detailed discussion of the tidal forces on a radially infalling observer. Basics of gravitational radiation are examined, highlighting the similarities to and differences from electromagnetic radiation. The final topics in Path I are equatorial geodesics in Kerr and the motion of a relativistic string in Minkowski space. Path II starts by introducing scalar field theory on Minkowski space as a limit of point masses connected by springs, emphasising the action principle, conservation laws and the energy-momentum tensor. The action principle for electromagnetism is introduced, and the coupling of electromagnetism to a complex scalar field is developed in a detailed and pedagogical fashion. A free symmetric second-rank tensor field on Minkowski space is introduced, and the action principle of general relativity is recovered from coupling the second-rank tensor to its own energy-momentum tensor. Path II then merges with Path I and, supplanted with judicious early selections from Path I, can proceed to the Schwarzschild solution. The choice of material in each path is logical and focused. A notable example in Path I is that Lorentz transformations in Minkowki space are introduced

  6. Limits of Generalizing in Education Research: Why Criteria for Research Generalization Should Include Population Heterogeneity and Uses of Knowledge Claims

    ERIC Educational Resources Information Center

    Ercikan, Kadriye; Roth, Wolff-Michael

    2014-01-01

    Context: Generalization is a critical concept in all research designed to generate knowledge that applies to all elements of a unit (population) while studying only a subset of these elements (sample). Commonly applied criteria for generalizing focus on experimental design or representativeness of samples of the population of units. The criteria…

  7. Multiple Biomarkers and Atrial Fibrillation in the General Population

    PubMed Central

    Schnabel, Renate B.; Wild, Philipp S.; Wilde, Sandra; Ojeda, Francisco M.; Schulz, Andreas; Zeller, Tanja; Sinning, Christoph R.; Kunde, Jan; Lackner, Karl J.

    2014-01-01

    Background Different biological pathways have been related to atrial fibrillation (AF). Novel biomarkers capturing inflammation, oxidative stress, and neurohumoral activation have not been investigated comprehensively in AF. Methods and Results In the population-based Gutenberg Health Study (n = 5000), mean age 56±11 years, 51% males, we measured ten biomarkers representing inflammation (C-reactive protein, fibrinogen), cardiac and vascular function (midregional pro adrenomedullin [MR-proADM], midregional pro atrial natriuretic peptide [MR-proANP], N-terminal pro-B-type natriuretic peptide [Nt-proBNP], sensitive troponin I ultra [TnI ultra], copeptin, and C-terminal pro endothelin-1), and oxidative stress (glutathioneperoxidase-1, myeloperoxidase) in relation to manifest AF (n = 161 cases). Individuals with AF were older, mean age 64.9±8.3, and more often males, 71.4%. In Bonferroni-adjusted multivariable regression analyses strongest associations per standard deviation increase in biomarker concentrations were observed for the natriuretic peptides Nt-proBNP (odds ratio [OR] 2.89, 99.5% confidence interval [CI] 2.14–3.90; P<0.0001), MR-proANP (OR 2.45, 99.5% CI 1.91–3.14; P<0.0001), the vascular function marker MR-proADM (OR 1.54, 99.5% CI 1.20–1.99; P<0.0001), TnI ultra (OR 1.50, 99.5% CI 1.19–1.90; P<0.0001) and. fibrinogen (OR 1.44, 99.5% CI 1.19–1.75; P<0.0001). Based on a model comprising known clinical risk factors for AF, all biomarkers combined resulted in a net reclassification improvement of 0.665 (99.3% CI 0.441–0.888) and an integrated discrimination improvement of >13%. Conclusions In conclusion, in our large, population-based study, we identified novel biomarkers reflecting vascular function, MR-proADM, inflammation, and myocardial damage, TnI ultra, as related to AF; the strong association of natriuretic peptides was confirmed. Prospective studies need to examine whether risk prediction of AF can be enhanced beyond clinical risk

  8. Antibiotics for the common cold: expectations of Germany's general population.

    PubMed

    Faber, M S; Heckenbach, K; Velasco, E; Eckmanns, T

    2010-09-02

    Physicians mention patients' expectations as a reason for prescribing antibiotics for common (viral) upper respiratory tract infections despite clinical evidence against their use and the physicians' better judgement. We aimed to assess the prevalence of such expectations and factors of influence (knowledge and attitudes) in Germany's general population. In November 2008, 1,778 persons registered with a large market research company were invited to complete an online questionnaire on expectations concerning prescription of antibiotics and on knowledge and attitudes regarding the effectiveness and use of antibiotics for upper respiratory tract infections. A total of 1,076 persons aged 15-78 years participated (response: 61%), of whom 91.8% reported using antibiotics 'only if absolutely necessary'. Prescription of antibiotics was expected by 113 (10.5%) of the 1,076 respondents for the common cold and by 997 (92.7%) for pneumonia. In a logistic regression analysis, predictors for expecting a prescription for antibiotics for the common cold included the following opinions: 'common cold or flu can effectively be treated with antibiotics' (prevalence: 37.6%; odds ratio (OR): 9.6; 95% confidence interval (CI): 3.8 to 24.3) and 'antibiotics should be taken when having a sore throat to prevent more serious illness' (prevalence 8.6%; OR: 7.6; 95% CI: 3.9 to 14.5). Among those expecting a prescription (n=113), 80 (71%) reported that they would trust their physician when he or she deems a prescription unnecessary; a further eight (7%) would be unsatisfied, but would accept the decision. Our results suggest that only a minority expects antibiotics for the treatment of cold symptoms. Physicians should be educated that their decisions not to prescribe antibiotics for the common cold, even when against patients' expectations, are apparently accepted by the majority.

  9. Schizotypy and specificity of negative emotions on an emotional Stroop paradigm in the general population.

    PubMed

    Yaffe, Beril; Walder, Deborah J

    2016-05-30

    Attentional-interference using emotional Stroop tasks (ESTs) is greater among individuals in the general population with positive (versus negative) schizotypal traits; specifically in response to negatively (versus positively) valenced words, potentially capturing threat-sensitivity. Variability in attentional-interference as a function of subcategories of negatively valenced words (and in relation to schizotypal traits) remains underexplored in EST studies. We examined attentional-interference across negative word subcategories (fear/anger/sadness/disgust), and in relation to positive schizotypy, among non-clinical individuals in the general population reporting varying degrees of schizotypal traits. As hypothesized, performance differed across word subcategories, though the pattern varied from expectation. Attentional-interference was greater for fear and sadness compared to anger; and analogous for fear, disgust, and sadness. In the high schizotypy group, positive schizotypal traits were directly associated with attentional-interference to disgust. Attentional-interference was comparable between high- and low-positive schizotypy. Results suggest negative emotion subcategories may differentially reflect threat-sensitivity. Disgust-sensitivity may be particularly salient in (non-clinical) positive schizotypy. Findings have implications for understanding negative emotion specificity and variability in stimulus presentation modality when studying threat-related attentional-interference. Finally, disgust-related attentional-interference may serve as a cognitive correlate of (non-clinical) positive schizotypy. Expanding this research to prodromal populations will help explore disgust-related attentional-interference as a potential cognitive marker of positive symptoms. PMID:27046393

  10. Comparison of Population Pyramid and Demographic Characteristics between People with an Intellectual Disability and the General Population

    ERIC Educational Resources Information Center

    Yen, Chia-Feng; Lin, Jin-Ding; Chiu, Tzu-Ying

    2013-01-01

    The purposes of this study were to measure disparities of age structure between people with an intellectual disability and general population, and to explore the difference of demographic characteristics between these two populations by using data from a population based register in Taiwan. Data were analyzed by SPSS 20.0 statistical software.…

  11. Season of birth and population schizotypy: Results from a large sample of the adult general population.

    PubMed

    Konrath, Lisa; Beckius, Danièle; Tran, Ulrich S

    2016-08-30

    Although the last years have seen an increasing interest in schizotypy and its pathogenesis, there exist only a handful of studies examining the possible interaction between season of birth (SOB) and schizotypic personality structure. Available research used differing screening instruments, rendering comparisons between studies difficult, and sample sizes in adult populations may have been too small to detect a mild effect. The current study examined the association between SOB and psychometric schizotypy in the so far single-largest sample from the adult general population (N=8114), balanced for men and women, and utilizing a valid and reliable instrument for the assessment of schizotypy. Using the 12 most informative items of the Schizotypal Personality Questionnaire Brief, we obtained evidence of a small, but significant, effect of late winter and early spring births (February/March) on psychometric schizotypy. The effect was not constrained to women, but affected men and women alike. The observed association between SOB and schizotypy appears compatible with seasonal variations of temperature and influenza prevalence, and with recent evidence on seasonal variability in the activity of the human immune system. Our findings lend support to the continuum hypothesis of schizotypy and schizophrenia, for which SOB effects have been previously established. PMID:27310922

  12. BOOK REVIEW: Equations of Motion in General Relativity Equations of Motion in General Relativity

    NASA Astrophysics Data System (ADS)

    Schäfer, Gerhard

    2012-03-01

    Devoted exclusively to the problem of motion in general relativity, this book by H. Asada, T. Futamase, and P. A. Hogan is highly welcome to close up a gap in the book sector presenting a concise account of theoretical developments and results on gravitational equations of motion achieved since the discovery of the binary neutron star system PSR 1913+16 in 1974. For the most part, the book is concerned with the development and application of the important post-Newtonian approximation (PNA) framework which allows for highly efficient approximate analytic solutions of the Einstein field equations for many-body systems in terms of a slow-motion and weak-field ordering parameter. That approximation scheme is shown to be applicable also to the external motion of strongly self-gravitating objects if their internal dynamics is frozen in (strong field point particle limit) and the external conditions fit. Relying on the expertise of the authors, the PNA framework is presented in a form which, at the 1PNA level, had become famous through the work by Einstein, Infeld and Hoffmann in 1938; therein, surface integrals over gravitational field expressions in the outside-body regime play a crucial role. Other approaches which also succeeded with the highest achieved PNA level so far are mentioned too, if not fully exhaustively with respect to the highest, the 3.5PNA level which contains the inverse power of the speed of light to the seventh order. Regarding the 3PNA, the reader gains a clear understanding of how the equations of motion for binary systems with compact components come about. Remarkably, no deviation from four-dimensional space-time is needed. Various explicit analytic expressions are derived for binary systems: the periastron advance and the orbital period at the 2PNA, the orbital decay through gravitational radiation reaction at the 2.5PNA, and effects of the gravitational spin-orbit and spin-spin couplings on the orbital motion. Also the propagation of light

  13. Interpolating a consumption variable for scaling and generalizing potential population pressure on urbanizing natural areas

    USGS Publications Warehouse

    Varanka, Dalia; Jiang, Bin; Yao, Xiaobai

    2010-01-01

    Measures of population pressure, referring in general to the stress upon the environment by human consumption of resources, are imperative for environmental sustainability studies and management. Development based on resource consumption is the predominant factor of population pressure. This paper presents a spatial model of population pressure by linking consumption associated with regional urbanism and ecosystem services. Maps representing relative geographic degree and extent of natural resource consumption and degree and extent of impacts on surrounding areas are new, and this research represents the theoretical research toward this goal. With development, such maps offer a visualization tool for planners of various services, amenities for people, and conservation planning for ecologist. Urbanization is commonly generalized by census numbers or impervious surface area. The potential geographical extent of urbanism encompasses the environmental resources of the surrounding region that sustain cities. This extent is interpolated using kriging of a variable based on population wealth data from the U.S. Census Bureau. When overlayed with land-use/land-cover data, the results indicate that the greatest estimates of population pressure fall within mixed forest areas. Mixed forest areas result from the spread of cedar woods in previously disturbed areas where further disturbance is then suppressed. Low density areas, such as suburbanization and abandoned farmland are characteristic of mixed forest areas.

  14. Genetic Risk for Attention-Deficit/Hyperactivity Disorder Contributes to Neurodevelopmental Traits in the General Population

    PubMed Central

    Martin, Joanna; Hamshere, Marian L.; Stergiakouli, Evangelia; O’Donovan, Michael C.; Thapar, Anita

    2014-01-01

    Background Attention-deficit/hyperactivity disorder (ADHD) can be viewed as the extreme end of traits in the general population. Epidemiological and twin studies suggest that ADHD frequently co-occurs with and shares genetic susceptibility with autism spectrum disorder (ASD) and ASD-related traits. The aims of this study were to determine whether a composite of common molecular genetic variants, previously found to be associated with clinically diagnosed ADHD, predicts ADHD and ASD-related traits in the general population. Methods Polygenic risk scores were calculated in the Avon Longitudinal Study of Parents and Children (ALSPAC) population sample (N = 8229) based on a discovery case-control genome-wide association study of childhood ADHD. Regression analyses were used to assess whether polygenic scores predicted ADHD traits and ASD-related measures (pragmatic language abilities and social cognition) in the ALSPAC sample. Polygenic scores were also compared in boys and girls endorsing any (rating ≥1) ADHD item (n = 3623). Results Polygenic risk for ADHD showed a positive association with ADHD traits (hyperactive-impulsive, p = .0039; inattentive, p = .037). Polygenic risk for ADHD was also negatively associated with pragmatic language abilities (p = .037) but not with social cognition (p = .43). In children with a rating ≥1 for ADHD traits, girls had a higher polygenic score than boys (p = .003). Conclusions These findings provide molecular genetic evidence that risk alleles for the categorical disorder of ADHD influence hyperactive-impulsive and attentional traits in the general population. The results further suggest that common genetic variation that contributes to ADHD diagnosis may also influence ASD-related traits, which at their extreme are a characteristic feature of ASD. PMID:24673882

  15. Trajectories of gambling problems from mid-adolescence to age 30 in a general population cohort.

    PubMed

    Carbonneau, René; Vitaro, Frank; Brendgen, Mara; Tremblay, Richard E

    2015-12-01

    Studies of gambling starting before adulthood in the general population are either cross-sectional, based on the stability of these behaviors between 2 time points, or cover a short developmental period. The present study aimed at investigating the developmental trajectories of gambling problems across 3 key periods of development, mid-adolescence, early adulthood, and age 30, in a mixed-gender cohort from the general population. Using a semiparametric mixture model, trajectories were computed based on self-reports collected at ages 15 (N = 1,882), 22 (N = 1,785), and 30 (N = 1,358). Two distinct trajectories were identified: 1 trajectory including males and females who were unlikely to have experienced gambling problems across the 15-year period, and 1 trajectory including participants likely to have experienced at least 1 problem over the last 12 months at each time of assessment. Participants following a high trajectory were predominantly male, participated frequently in 3 to 4 different gambling activities, and were more likely to report substance use and problems related to their alcohol and drug consumption at age 30. Thus, gambling problems in the general population are already observable at age 15 in a small group of individuals, who maintain some level of these problems through early adulthood, before moderately but significantly desisting by age 30, while also experiencing other addictive behaviors and related problems. PMID:26168229

  16. Self-reported psychopathic traits in sexually offending juveniles compared with generally offending juveniles and general population youth.

    PubMed

    Boonmann, Cyril; Jansen, Lucres M C; 't Hart-Kerkhoffs, Lisette A; Vahl, Pauline; Hillege, Sanne L; Doreleijers, Theo A H; Vermeiren, Robert R J M

    2015-01-01

    The aim of the current study is to gain a better insight into the relationship between sexually aggressive behaviour and psychopathy in youths; juveniles who sexually offended (JSOs) were compared with generally offending youths and a general population group. Seventy-one JSOs, 416 detained general offenders, and 331 males from the general population were assessed by means of the Youth Psychopathic traits Inventory (YPI), a self-report instrument. Sexually and generally offending juveniles had significantly lower levels of self-reported psychopathic traits than youths from the general population. Juvenile sexual offenders and generally offending juveniles did not differ in self-reported psychopathic traits. Furthermore, no differences in self-reported psychopathic traits were found between subgroups of JSOs (i.e., child molesters, solo offenders, and group offenders). The finding that self-reported psychopathic traits are less prevalent in offending juveniles than in general population youths raises questions about the usefulness of the YPI when comparing psychopathic traits between clinical samples and general-population samples.

  17. [The HLA system in the Moroccan population: General review].

    PubMed

    Brick, C; Atouf, O; Essakalli, M

    2015-01-01

    The Moroccan population is an interesting study model of Human Leukocyte Antigen (HLA) polymorphism given its ethnic and genetic diversity. Through an analysis of the literature, this work proposes to establish a balance of knowledge for this population in the field of histocompatibility: HLA diversity, anthropology, transplantation and HLA associations and diseases. This analysis shows that the HLA system has not been fully explored within the Moroccan population. However, the results obtained allowed us to initiate a database reflecting the specific healthy Moroccan population HLA polymorphism to identify immigration flows and relationships with different people of the world and to reveal the association of certain HLA alleles with frequent pathologies. We also propose to analyze the reasons hindering the development of this activity in Morocco and we will try to identify some perspectives. PMID:26597780

  18. Stochastic resonance in a generalized Von Foerster population growth model

    SciTech Connect

    Lumi, N.; Mankin, R.

    2014-11-12

    The stochastic dynamics of a population growth model, similar to the Von Foerster model for human population, is studied. The influence of fluctuating environment on the carrying capacity is modeled as a multiplicative dichotomous noise. It is established that an interplay between nonlinearity and environmental fluctuations can cause single unidirectional discontinuous transitions of the mean population size versus the noise amplitude, i.e., an increase of noise amplitude can induce a jump from a state with a moderate number of individuals to that with a very large number, while by decreasing the noise amplitude an opposite transition cannot be effected. An analytical expression of the mean escape time for such transitions is found. Particularly, it is shown that the mean transition time exhibits a strong minimum at intermediate values of noise correlation time, i.e., the phenomenon of stochastic resonance occurs. Applications of the results in ecology are also discussed.

  19. Ischemic heart disease among the general Mongolian population: a review of epidemiological studies.

    PubMed

    Enkh-Oyun, Tsogzolbaatar; Kotani, Kazuhiko; Swanson, Eric

    2016-01-01

    Ischemic heart disease (IHD) is considered to be a pivotal health problem in Mongolia. To summarize the existing epidemiology of IHD in the general Mongolian population is crucial for primary prevention. The present review summarized population-based epidemiological data of IHD in Mongolia. When epidemiological studies were extracted from databases, very limited studies were available. The frequencies of IHD and IHD-attributable death rates appeared to be high and have an increased tendency in Mongolia. This could to be due to a gradually worsening state of potential IHD-related risk factors, such as smoking, hypertension, hypercholesterolemia, obesity and diabetes mellitus. This might indicate an urgent need of strategies for IHD and related risk factors. Anti-IHD strategies, such as more epidemiological studies and campaigns to increase awareness of IHD, at nationwide public health levels would be required in Mongolia for more effective prevention.

  20. Modelo de Alfabetizacion: A Poblacion Urbana y Rural. Documento General (Literacy Model: Urban and Rural Populations. General Document).

    ERIC Educational Resources Information Center

    Instituto Nacional para la Educacion de los Adultos, Mexico City (Mexico).

    This document describes literacy models for urban and rural populations in Mexico. It contains four sections. The first two sections (generalizations about the population and considerations about the teaching of adults) discuss the environment that creates illiterate adults and also describe some of the conditions under which learning takes place…

  1. Is chrysotile asbestos exposure a significant health risk to the general population?

    PubMed

    Valić, F; Beritic-Stahuljak, D

    1993-06-01

    The main unresolved issues concerning environmental exposure to chrysotile asbestos of the general population are discussed. A review of the results of the measurement of airborne chrysotile fibres in buildings is presented showing that the results have been consistently low with the exception of buildings with damaged friable asbestos-containing material. Quantitative risk assessments are presented indicating that the lifetime risk is small compared to many other environmental risks. Possible adverse health effects of paraoccupational exposures in the case of high domestic airborne asbestos levels cannot be excluded. Both on the basis of electron microscopy analyses of asbestos exposures at locations with heavy traffic, and the very shallow slopes in the exposure-response relationships for increased lung cancer risk, the conclusion is drawn that exposure to airborne asbestos-containing friction materials has not been proven to pose a significant health risk to the general population. Reviewing animal ingestion studies published and all the available epidemiological studies related to asbestos in drinking water, the conclusion is drawn that the carcinogenic risk in the general population is low even in the case of drinking water containing elevated concentrations of chrysotile asbestos.

  2. Assessing Methods for Generalizing Experimental Impact Estimates to Target Populations

    ERIC Educational Resources Information Center

    Kern, Holger L.; Stuart, Elizabeth A.; Hill, Jennifer; Green, Donald P.

    2016-01-01

    Randomized experiments are considered the gold standard for causal inference because they can provide unbiased estimates of treatment effects for the experimental participants. However, researchers and policymakers are often interested in using a specific experiment to inform decisions about other target populations. In education research,…

  3. Environmental Pollution Control: Two Views from the General Population

    ERIC Educational Resources Information Center

    Althoff, Phillip; Greig, William H.

    1977-01-01

    Citizens exhibitied concern about pollution, a low level of trust in governmental and industrial efforts, and a low level of dedication to environmental protection. Demands to clean up the environment came from one segment of the population while demands to solve the energy crisis came from other segments. (AJ)

  4. Long-term survival following intensive care: subgroup analysis and comparison with the general population.

    PubMed

    Wright, J C; Plenderleith, L; Ridley, S A

    2003-07-01

    This study aimed to compare the very long-term survival of critically ill patients with that of the general population, and examine the association among age, sex, admission diagnosis, APACHE II score and mortality. In a retrospective observational cohort study of prospectively gathered data, 2104 adult patients admitted to the intensive care unit (ICU) of a teaching hospital in Glasgow from 1985 to 1992, were followed until 1997. Vital status at five years was compared with that of an age- and sex-matched Scottish population. Five-year mortality for the ICU patients was 47.1%, 3.4 times higher than that of the general population. For those surviving intensive care the five-year mortality was 33.4%. Mortality was greater than that of the general population for four years following intensive care unit admission (95% confidence interval included 1.0 at four years). Multivariate analysis showed that risk factors for mortality in those admitted to ICU were age, APACHE II score on admission and diagnostic category. Mortality was higher for those admitted with haematological (87.5%) and neurological diseases (61.7%) and septic shock (62.9%). A risk score was produced: Risk Score = 10 (age hazard ratio + APACHE II hazard ratio + diagnosis hazard ratio). None of the patients with a risk score > 100 survived more than five years and for those who survived to five years the mean risk score was 57. Long-term survival following intensive care is not only related to age and severity of illness but also diagnostic category. The risk of mortality in survivors of critical illness matches that of the normal population after four years. Age, severity of illness and diagnosis can be combined to provide an estimate of five-year survival.

  5. [Analysis of the definitive statistics of the 11th General Population and Housing Census].

    PubMed

    Aguayo Hernandez, J R

    1992-01-01

    The 11th General Census of Population and Housing conducted in March 1990 enumerated 2,204,054 inhabitants in Sinaloa, for a density of 37.9 per sq. km. Sinaloa's population thus increased sevenfold from 297,000 in 1900. The proportion of Sinalioans in Mexico's population increased from 2.2% in 1900 to 2.7% in 1990. 38.4% of the population was under age 14, 57.0% was 14064, and 4.6% as over 65. The greatest challenge for the year 2010 will be to meet the demand for educational facilities, employment, and services for the growing elderly population. Sinaloa's population grew at an annual rate of 1.1 between 1980-90. 17 of its 18 municipios showed slowing growth rates between 1980-90, with only Escuinapa increasing its rate. Sinaloa's growth rate of 1.8% is still relatively high, and the population in the year 2000 is projected at 2.6 million. Population distribution and migration present problems that should be more actively addressed. Urban-urban migration is increasing in importance. In 1990, Sinaloa had 5247 localities of which only 85 had more than 2500 inhabitants and 4717 had fewer than 500. Growth of midsize localities with 500-2499 inhabitants may constitute an alternative allowing the demographic deconcentration and decentralization that Sinaloa urgently requires. The lack of jobs, infrastructure, educational and health services, housing, and food in the dispersed 4717 communities with fewer than 500 inhabitants makes them sources of emigration. Sinaloa's population is concentrated along the coast and in the 3 valleys of the north and central regions, which contain 80.8% of the population. One-third of the population lives on 12.1% of the territory in 2 municipios, while 12 municipios covering 67% of the territory contain just 24% of the population. Sinaloa's growth rate has declined from 4.3% between 1960-70 to 3.7% from 1970-80 and 1.8% in 1980-90.

  6. 2. GENERAL VIEW SOUTHEAST DEPICTING THE RELATION (LEFT TO RIGHT) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. GENERAL VIEW SOUTHEAST DEPICTING THE RELATION (LEFT TO RIGHT) OF 25, 35, 119 AND 125 CONTRA COSTA ST. - Point Richmond Historic District, Hillside & Contra Costa Streets, Richmond, Contra Costa County, CA

  7. 2. GENERAL VIEW SHOWING RELATION OF BRIDGE TO THE TOPOGRAPHY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. GENERAL VIEW SHOWING RELATION OF BRIDGE TO THE TOPOGRAPHY OF THE APPROACH ROAD. - Speicher Bridge, Church Road over Tulpehocken Creek between Penn & North Heidelberg Townships, Bernville, Berks County, PA

  8. RELATIONSHIPS BETWEEN LEVELS OF VOLATILE ORGANIC COMPOUNDS IN AIR AND BLOOD FROM THE GENERAL POPULATION

    EPA Science Inventory

    Background: The relationships between levels of volatile organic compounds (VOCs) in blood and air have not been well characterized in the general population where exposure concentrations are generally at ppb levels. Objectives: This study investigates relationships between ...

  9. The magnetosheath electron population at lunar distance - General features

    NASA Technical Reports Server (NTRS)

    Reiff, P. H.; Reasoner, D. L.

    1975-01-01

    A study was made of the electron population in the earth's magnetosheath at lunar distance. The data used were collected by the Apollo 14 charged particle lunar environment experiment (CPLEE) during four inbound (dusk) and three outbound (dawn) passages of the moon through the magnetosheath. The magnetotail has a diameter of 52 earth radii, while the bow-shock cross section is about 91 earth radii. The average boundary locations computed from the complete data set are consistent with the prediction of fluid dynamics. The electron characteristics for the two least-disturbed passages are presented in detail. An examination of the energy spectra shows that a high-energy (200-2000 eV) tail is superimposed on the expected low-energy (40-200 eV) magnetosheath distribution. It is argued that the high-energy magnetosheath electron population originates at the bow shock, rather than from the plasma sheet.

  10. ECOLOGICAL THEORY. A general consumer-resource population model.

    PubMed

    Lafferty, Kevin D; DeLeo, Giulio; Briggs, Cheryl J; Dobson, Andrew P; Gross, Thilo; Kuris, Armand M

    2015-08-21

    Food-web dynamics arise from predator-prey, parasite-host, and herbivore-plant interactions. Models for such interactions include up to three consumer activity states (questing, attacking, consuming) and up to four resource response states (susceptible, exposed, ingested, resistant). Articulating these states into a general model allows for dissecting, comparing, and deriving consumer-resource models. We specify this general model for 11 generic consumer strategies that group mathematically into predators, parasites, and micropredators and then derive conditions for consumer success, including a universal saturating functional response. We further show how to use this framework to create simple models with a common mathematical lineage and transparent assumptions. Underlying assumptions, missing elements, and composite parameters are revealed when classic consumer-resource models are derived from the general model.

  11. General and specific components of depression and anxiety in an adolescent population

    PubMed Central

    2011-01-01

    Background Depressive and anxiety symptoms often co-occur resulting in a debate about common and distinct features of depression and anxiety. Methods An exploratory factor analysis (EFA) and a bifactor modelling approach were used to separate a general distress continuum from more specific sub-domains of depression and anxiety in an adolescent community sample (n = 1159, age 14). The Mood and Feelings Questionnaire and the Revised Children's Manifest Anxiety Scale were used. Results A three-factor confirmatory factor analysis is reported which identified a) mood and social-cognitive symptoms of depression, b) worrying symptoms, and c) somatic and information-processing symptoms as distinct yet closely related constructs. Subsequent bifactor modelling supported a general distress factor which accounted for the communality of the depression and anxiety items. Specific factors for hopelessness-suicidal thoughts and restlessness-fatigue indicated distinct psychopathological constructs which account for unique information over and above the general distress factor. The general distress factor and the hopelessness-suicidal factor were more severe in females but the restlessness-fatigue factor worse in males. Measurement precision of the general distress factor was higher and spanned a wider range of the population than any of the three first-order factors. Conclusions The general distress factor provides the most reliable target for epidemiological analysis but specific factors may help to refine valid phenotype dimensions for aetiological research and assist in prognostic modelling of future psychiatric episodes. PMID:22151586

  12. Introduction to General Relativity and John Archibald Wheeler

    NASA Astrophysics Data System (ADS)

    Ciufolini, Ignazio; Matzner, Richard

    John Archibald Wheeler was born on July 9, 1911, in Jacksonville, Florida, and passed away on April 13, 2008, in Hightstown, New Jersey; his influence on gravitational physics and science in general will remain forever. Among his many and important contributions to physics, he was one of the fathers of the renaissance of General Relativity. After a golden starting age of General Relativity, a few years after the Einstein's papers of 1915-1916, Einstein's gravitational theory was for many years, to quote the preface of a 1960 book of General Relativity [1], confined to "an ivory tower…and no doubt many a relativist looks forward to the day when the governments will seek his opinion on important questions".

  13. The general class of the vacuum spherically symmetric equations of the general relativity theory

    SciTech Connect

    Karbanovski, V. V. Sorokin, O. M.; Nesterova, M. I.; Bolotnyaya, V. A.; Markov, V. N. Kairov, T. V.; Lyash, A. A.; Tarasyuk, O. R.

    2012-08-15

    The system of the spherical-symmetric vacuum equations of the General Relativity Theory is considered. The general solution to a problem representing two classes of line elements with arbitrary functions g{sub 00} and g{sub 22} is obtained. The properties of the found solutions are analyzed.

  14. Generalized Uncertainty Relation in the Non-commutative Quantum Mechanics

    NASA Astrophysics Data System (ADS)

    Chung, Won Sang

    2016-06-01

    In this paper the non-commutative quantum mechanics (NCQM) with the generalized uncertainty relations {Δ } x1 {Δ } x2 ≥ {θ}/{2}, {Δ} p1 {Δ } p2 ≥ {bar{θ}}/{2}, {Δ } xi {Δ } pi ≥ {hbar _{eff}}/{2} is discussed. Four each uncertainty relation, wave functions saturating each uncertainty relation are explicitly constructed. The unitary operators relating the non-commutative position and momentum operators to the commutative position and momentum operators are also investigated. We also discuss the uncertainty relation related to the harmonic oscillator.

  15. On Clifford Space Relativity, Black Hole Entropy, Rainbow Metrics, Generalized Dispersion and Uncertainty Relations

    NASA Astrophysics Data System (ADS)

    Castro, Carlos

    2014-09-01

    An analysis of some of the applications of Clifford space relativity to the physics behind the modified black hole entropy-area relations, rainbow metrics, generalized dispersion and minimal length stringy uncertainty relations is presented.

  16. Alcohol consumption among the elderly in a general population, Erie County, New York.

    PubMed Central

    Mirand, A L; Welte, J W

    1996-01-01

    OBJECTIVES. Relatively few studies of drinking among the elderly have been completed despite the growing proportional representation of the elderly in the US population. This study sought to estimate the prevalence of and to observe whether active or health-oriented lifestyles are associated with heavy drinking among the elderly. METHODS. Random-digit dialing telephone interviews were conducted with 2325 Erie County, New York, general population residents aged 60 years or older. RESULTS. The prevalence of heavy drinking was 6%. Adjusted analyses showed positive associations between heavy drinking and being male, having suburban residency, and currently using cigarettes. Negative relationships were observed between heavy drinking and socioeconomic status, rural residency, and degree of health orientation. Age and level of active lifestyle were not significant contributors to the model. CONCLUSIONS. Of the studied variables, health orientation offers the greatest opportunity to address heavy drinking among the elderly. PMID:8669522

  17. Pressure to change drinking behavior: An exploratory analysis of US general population subgroups

    PubMed Central

    Polcin, Douglas L.; Greenfield, Thomas K.; Kerr, William C.; Bond, Jason

    2014-01-01

    Background General population studies have shown that pressure from others to change drinking can come from different sources. Receipt of informal pressure (IP) and formal pressure (FP) is known to vary by quantity and consequences of drinking, but less is known about how pressure varies among subgroups of the population. Method This exploratory study utilizes data from the National Alcohol Surveys from 1995–2010 (N=26,311) and examines associations between receipt of pressure and subgroups of drinkers. Results Increased relative risk of receiving IP and FP were observed for individuals reporting an arrest for driving after drinking and illicit drug use while poverty and lack of private health insurance increased risk of receipt of formal pressures. Regular marijuana use increased IP. Conclusion The subgroups that were studied received increased pressures to change drinking behavior, though disentangling the societal role of pressure and how it may assist with interventions, help seeking, and natural recovery is needed. PMID:25346550

  18. Intimate Partner Violence among General and Urban Poor Populations in Kathmandu, Nepal

    ERIC Educational Resources Information Center

    Oshiro, Azusa; Poudyal, Amod K.; Poudel, Krishna C.; Jimba, Masamine; Hokama, Tomiko

    2011-01-01

    Comparative studies are lacking on intimate partner violence (IPV) between urban poor and general populations. The objective of this study is to identify the prevalence and risk factors of physical IPV among the general and poor populations in urban Nepal. A cross-sectional study was conducted by structured questionnaire interview. Participants…

  19. Correlates of Peripheral Blood Mitochondrial DNA Content in a General Population

    PubMed Central

    Knez, Judita; Winckelmans, Ellen; Plusquin, Michelle; Thijs, Lutgarde; Cauwenberghs, Nicholas; Gu, Yumei; Staessen, Jan A.; Nawrot, Tim S.; Kuznetsova, Tatiana

    2016-01-01

    Accumulation of mitochondrial DNA (mtDNA) mutations leads to alterations of mitochondrial biogenesis and function that might produce a decrease in mtDNA content within cells. This implies that mtDNA content might be a potential biomarker associated with oxidative stress and inflammation. However, data on correlates of mtDNA content in a general population are sparse. Our goal in the present study was to describe in a randomly recruited population sample the distribution and determinants of peripheral blood mtDNA content. From 2009 to 2013, we examined 689 persons (50.4% women; mean age = 54.4 years) randomly selected from a Flemish population (Flemish Study on Environment, Genes, and Health Outcomes). Relative mtDNA copy number as compared with nuclear DNA was measured by quantitative real-time polymerase chain reaction in peripheral blood. There was a curvilinear relationship between relative mtDNA copy number and age. mtDNA content slightly increased until the fifth decade of life and declined in older subjects (Page2 = 0.0002). mtDNA content was significantly higher in women (P = 0.007) and increased with platelet count (P < 0.0001), whereas it was inversely associated with white blood cell count (P < 0.0001). We also observed lower mtDNA content in women using estroprogestogens (P = 0.044). This study demonstrated in a general population that peripheral blood mtDNA content is significantly associated with sex and age. Blood mtDNA content is also influenced by platelet and white blood cell counts and estroprogestogen intake. Further studies are required to clarify the impact of chronic inflammation and hormone therapy on mitochondrial function. PMID:26702630

  20. Prevalence of hallucinations and their pathological associations in the general population.

    PubMed

    Ohayon, M M

    2000-12-27

    Hallucinations are perceptual phenomena involved in many fields of pathology. Although clinically widely explored, studies in the general population of these phenomena are scant. This issue was investigated using representative samples of the non-institutionalized general population of the United Kingdom, Germany and Italy aged 15 years or over (N=13,057). These surveys were conducted by telephone and explored mental disorders and hallucinations (visual, auditory, olfactory, haptic and gustatory hallucinations, out-of-body experiences, hypnagogic and hypnopompic hallucinations). Overall, 38.7% of the sample reported hallucinatory experiences (19.6% less than once in a month; 6.4% monthly; 2.7% once a week; and 2.4% more than once a week). These hallucinations occurred, (1) At sleep onset (hypnagogic hallucinations 24.8%) and/or upon awakening (hypnopompic hallucinations 6.6%), without relationship to a specific pathology in more than half of the cases; frightening hallucinations were more often the expression of sleep or mental disorders such as narcolepsy, OSAS or anxiety disorders. (2) During the daytime and reported by 27% of the sample: visual (prevalence of 3.2%) and auditory (0.6%) hallucinations were strongly related to a psychotic pathology (respective OR of 6.6 and 5.1 with a conservative estimate of the lifetime prevalence of psychotic disorders in this sample of 0.5%); and to anxiety (respective OR of 5.0 and 9.1). Haptic hallucinations were reported by 3.1% with current use of drugs as the highest risk factor (OR=9.8). In conclusion, the prevalence of hallucinations in the general population is not negligible. Daytime visual and auditory hallucinations are associated with a greater risk of psychiatric disorders. The other daytime sensory hallucinations are more related to an organic or a toxic disorder.

  1. Predicting acute maxillary sinusitis in a general practice population.

    PubMed Central

    Hansen, J. G.; Schmidt, H.; Rosborg, J.; Lund, E.

    1995-01-01

    OBJECTIVE--To evaluate the diagnostic value of symptoms, signs, erythrocyte sedimentation rate, and C reactive protein for acute maxillary sinusitis. DESIGN--Prospective cohort study. SETTING--Danish general practice in cooperation with the otorhinolaryngology and neuroradiology department at Aalborg County Hospital. SUBJECTS--174 patients aged 18-65 years who were suspected by the general practitioner of having acute maxillary sinusitis. MAIN OUTCOME MEASURE--The independent association of symptoms, signs, erythrocyte sedimentation rate, and concentration of C reactive protein in patients with acute maxillary sinusitis defined as purulent or mucopurulent antral aspirate. RESULTS--Only raised erythrocyte sedimentation rate (P = 0.01) and raised C reactive protein (P = 0.007) were found to be independently associated with a diagnosis of acute maxillary sinusitis. The combination of the two variables had a sensitivity of 0.82 and a specificity of 0.57. CONCLUSION--Erythrocyte sedimentation rate and C reactive protein are useful diagnostic criteria for acute maxillary sinusitis. PMID:7627042

  2. Matroidal Structure of Generalized Rough Sets Based on Tolerance Relations

    PubMed Central

    Li, Hui; Liu, Yanfang

    2014-01-01

    Rough set theory provides an effective tool to deal with uncertain, granular, and incomplete knowledge in information systems. Matroid theory generalizes the linear independence in vector spaces and has many applications in diverse fields, such as combinatorial optimization and rough sets. In this paper, we construct a matroidal structure of the generalized rough set based on a tolerance relation. First, a family of sets are constructed through the lower approximation of a tolerance relation and they are proved to satisfy the circuit axioms of matroids. Thus we establish a matroid with the family of sets as its circuits. Second, we study the properties of the matroid including the base and the rank function. Moreover, we investigate the relationship between the upper approximation operator based on a tolerance relation and the closure operator of the matroid induced by the tolerance relation. Finally, from a tolerance relation, we can get a matroid of the generalized rough set based on the tolerance relation. The matroid can also induce a new relation. We investigate the connection between the original tolerance relation and the induced relation. PMID:25162044

  3. Celebrity Suicides and Their Differential Influence on Suicides in the General Population: A National Population-Based Study in Korea

    PubMed Central

    Myung, Woojae; Won, Hong-Hee; Fava, Maurizio; Mischoulon, David; Yeung, Albert; Lee, Dongsoo; Kim, Doh Kwan

    2015-01-01

    Objective Although evidence suggests that there is an increase in suicide rates in the general population following celebrity suicide, the rates are heterogeneous across celebrities and countries. It is unclear which is the more vulnerable population according to the effect sizes of celebrity suicides to general population. Methods All suicide victims in the general population verified by the Korea National Statistical Office and suicides of celebrity in South Korea were included for 7 years from 2005 to 2011. Effect sizes were estimated by comparing rates of suicide in the population one month before and after each celebrity suicide. The associations between suicide victims and celebrities were examined. Results Among 94,845 suicide victims, 17,209 completed suicide within one month after 13 celebrity suicides. Multivariate logistic regression analyses revealed that suicide victims who died after celebrity suicide were significantly likely to be of age 20-39, female, and to die by hanging. These qualities were more strongly associated among those who followed celebrity suicide with intermediate and high effect sizes than lower. Younger suicide victims were significantly associated with higher effect size, female gender, white collar employment, unmarried status, higher education, death by hanging, and night-time death. Characteristics of celebrities were significantly associated with those of general population in hanging method and gender. Conclusion Individuals who commit suicide after a celebrity suicide are likely to be younger, female, and prefer hanging as method of suicide, which are more strongly associated in higher effect sizes of celebrity suicide. PMID:25866521

  4. The relationship between iodine intake and serum thyroglobulin in the general population.

    PubMed

    Bílek, R; Čeřovská, J; Zamrazil, V

    2015-01-01

    The relationship is shown between a concentration of urinary iodine and serum thyroglobulin in population studies carried out on a general population that was randomly selected from the registry of the General Health Insurance Company (individuals aged 6-98 years, 1751 males, 2420 females). The individuals were divided into subgroups with a urinary iodine concentration of <50, 50-99, 100-199, 200-299 and >/=300 microg/l. The mean and median of thyroglobulin were calculated in these subgroups. Tg concentrations were dependent on gender (malesrelation to iodine intake were calculated in subgroup of normal individuals (n=1858, thyroglobulin, urinary iodine, thyrotropin and free thyroxine were within the normal reference range). Upper limits were dependent on gender and age. The total value of upper limits is 44 microg/l; for individuals aged 6-17 years it is 39.1 microg/l; 18-65 years = 51.4 microg/l and 66-98 years = 60.6 microg/l. In general, thyroglobulin serum concentrations higher than 40 microg/l should be an indicator for determining urinary iodine.

  5. Simulations of accretion disks in pseudo-complex General Relativity

    NASA Astrophysics Data System (ADS)

    Hess, P. O.; Algalán B., M.; Schönenbach, T.; Greiner, W.

    2015-11-01

    After a summary on pseudo-complex General Relativity (pc-GR), circular orbits and stable orbits in general are discussed, including predictions compared to observations. Using a modified version of a model for accretions disks, presented by Page and Thorne in 1974, we apply the raytracing technique in order to simulate the appearance of an accretion disk as it should be observed in a detector. In pc-GR we predict a dark ring near a very massive, rapidly rotating object.

  6. A general population genetic framework for antagonistic selection that accounts for demography and recurrent mutation.

    PubMed

    Connallon, Tim; Clark, Andrew G

    2012-04-01

    Antagonistic selection--where alleles at a locus have opposing effects on male and female fitness ("sexual antagonism") or between components of fitness ("antagonistic pleiotropy")--might play an important role in maintaining population genetic variation and in driving phylogenetic and genomic patterns of sexual dimorphism and life-history evolution. While prior theory has thoroughly characterized the conditions necessary for antagonistic balancing selection to operate, we currently know little about the evolutionary interactions between antagonistic selection, recurrent mutation, and genetic drift, which should collectively shape empirical patterns of genetic variation. To fill this void, we developed and analyzed a series of population genetic models that simultaneously incorporate these processes. Our models identify two general properties of antagonistically selected loci. First, antagonistic selection inflates heterozygosity and fitness variance across a broad parameter range--a result that applies to alleles maintained by balancing selection and by recurrent mutation. Second, effective population size and genetic drift profoundly affect the statistical frequency distributions of antagonistically selected alleles. The "efficacy" of antagonistic selection (i.e., its tendency to dominate over genetic drift) is extremely weak relative to classical models, such as directional selection and overdominance. Alleles meeting traditional criteria for strong selection (N(e)s > 1, where N(e) is the effective population size, and s is a selection coefficient for a given sex or fitness component) may nevertheless evolve as if neutral. The effects of mutation and demography may generate population differences in overall levels of antagonistic fitness variation, as well as molecular population genetic signatures of balancing selection. PMID:22298707

  7. Quaternionic quantization principle in general relativity and supergravity

    NASA Astrophysics Data System (ADS)

    Kober, Martin

    2016-01-01

    A generalized quantization principle is considered, which incorporates nontrivial commutation relations of the components of the variables of the quantized theory with the components of the corresponding canonical conjugated momenta referring to other space-time directions. The corresponding commutation relations are formulated by using quaternions. At the beginning, this extended quantization concept is applied to the variables of quantum mechanics. The resulting Dirac equation and the corresponding generalized expression for plane waves are formulated and some consequences for quantum field theory are considered. Later, the quaternionic quantization principle is transferred to canonical quantum gravity. Within quantum geometrodynamics as well as the Ashtekar formalism, the generalized algebraic properties of the operators describing the gravitational observables and the corresponding quantum constraints implied by the generalized representations of these operators are determined. The generalized algebra also induces commutation relations of the several components of the quantized variables with each other. Finally, the quaternionic quantization procedure is also transferred to 𝒩 = 1 supergravity. Accordingly, the quantization principle has to be generalized to be compatible with Dirac brackets, which appear in canonical quantum supergravity.

  8. Prevalence of auditory verbal hallucinations in a general population: A group comparison study.

    PubMed

    Kråkvik, Bodil; Larøi, Frank; Kalhovde, Anne Martha; Hugdahl, Kenneth; Kompus, Kristiina; Salvesen, Øyvind; Stiles, Tore C; Vedul-Kjelsås, Einar

    2015-10-01

    The present study was specifically designed to investigate the prevalence of auditory verbal hallucinations (AVH) in the general population, and sought to compare similarities and differences regarding socio-demographics, mental health and severe life events between individuals who have never experienced AVH with those who had. The study also aimed to compare those who sought professional help for their experience of AVH with those who had not sought help. Through a postal questionnaire, 2,533 participants ages 18 and over from a national survey completed the Launay-Slade Hallucinations Scale and other measures examining AVH characteristics and other areas related to AVH. In total, 7.3% of the sample reported a life-time prevalence of AVH. Those with AVH were more likely to be single and unemployed, reported higher levels of depression and anxiety, and experienced a higher number of severe life events compared with those without AVH. Only 16% of those who experienced AVH in the general population sought professional help for these experiences. Compared to those who did not seek professional help, participants that had were more likely to experience AVH with a negative content, experience them on a daily basis, undergo negative reactions when experiencing AVH, and resist AVH. In conclusion, the prevalence of AVH was found to be relatively high. The results also revealed higher levels of reduced mental health for individuals who sought professional help, followed by those who did not, compared with those who had never experienced AVH. PMID:26079977

  9. The Role of Self-Compassion in Buffering Symptoms of Depression in the General Population

    PubMed Central

    Körner, Annett; Coroiu, Adina; Copeland, Laura; Gomez-Garibello, Carlos; Albani, Cornelia; Zenger, Markus; Brähler, Elmar

    2015-01-01

    Self-compassion, typically operationalized as the total score of the Self-Compassion Scale (SCS; Neff, 2003b), has been shown to be related to increased psychological well-being and lower depression in students of the social sciences, users of psychology websites and psychotherapy patients. The current study builds on the existing literature by examining the link between self-compassion and depressive symptomatology in a sample representative of the German general population (n = 2,404). The SCS subscales of self-judgment, isolation, and over-identification, and the “self-coldness”, composite score, which encompass these three negative subscales, consistently differed between subsamples of individuals without any depressive symptoms, with any depressive syndromes, and with major depressive disorder. The contribution of the positive SCS subscales of self-kindness, common humanity, and mindfulness to the variance in depressive symptomatology was almost negligible. However, when combined to a “self-compassion composite”, the positive SCS subscales significantly moderated the relationship between “self-coldness” and depressive symptoms in the general population. This speaks for self-compassion having the potential to buffer self-coldness related to depression—providing an argument for interventions that foster self-caring, kind, and forgiving attitudes towards oneself. PMID:26430893

  10. Gender Differences in Depressive Symptom Profile: Results from Nationwide General Population Surveys in Korea.

    PubMed

    Kim, Ji-Hyun; Cho, Maeng Je; Hong, Jin Pyo; Bae, Jae Nam; Cho, Seong-Jin; Hahm, Bong-Jin; Lee, Dong-Woo; Park, Jong-Ik; Lee, Jun-Young; Jeon, Hong Jin; Chang, Sung Man

    2015-11-01

    This study investigated gender differences in symptom profiles of major depressive disorder (MDD) in the Korean general population. Data were pooled from the series of nationwide Korean Epidemiologic Catchment Area surveys conducted in 2001, 2006 and 2011, respectively. Of the 18,807 participants, 507 (397 women and 110 men) were diagnosed with MDD within the prior 12 months. In agreement with previous studies, women with MDD appeared to be more vulnerable to experiencing atypical depressive episodes defined as depression with two or more symptoms of fatigue, increased appetite and hypersomnia (P < 0.001). In terms of individual symptoms, female gender was significantly related with higher prevalence of fatigue (P = 0.008), hypersomnia (P = 0.001), noticeable psychomotor retardation (P = 0.029) and suicidal attempts (P = 0.016) with adjustment for birth cohort effect, partner status, and employment status. In the same analysis, men with MDD appeared more vulnerable to decreased libido than women (P = 0.009). This is the first report to demonstrate gender differences in symptomatology of MDD in the general Korean population, and the results are comparable to previous investigations from western societies. Assumingly, the intercultural similarity in female preponderance to atypical depression might reflect the common biological construct underlying the gender difference in mechanism of MDD. In clinical settings, gender differences of MDD should be carefully considered, because these features could be related with treatment response and drug side effects. PMID:26539012

  11. The Role of Self-Compassion in Buffering Symptoms of Depression in the General Population.

    PubMed

    Körner, Annett; Coroiu, Adina; Copeland, Laura; Gomez-Garibello, Carlos; Albani, Cornelia; Zenger, Markus; Brähler, Elmar

    2015-01-01

    Self-compassion, typically operationalized as the total score of the Self-Compassion Scale (SCS; Neff, 2003b), has been shown to be related to increased psychological well-being and lower depression in students of the social sciences, users of psychology websites and psychotherapy patients. The current study builds on the existing literature by examining the link between self-compassion and depressive symptomatology in a sample representative of the German general population (n = 2,404). The SCS subscales of self-judgment, isolation, and over-identification, and the "self-coldness", composite score, which encompass these three negative subscales, consistently differed between subsamples of individuals without any depressive symptoms, with any depressive syndromes, and with major depressive disorder. The contribution of the positive SCS subscales of self-kindness, common humanity, and mindfulness to the variance in depressive symptomatology was almost negligible. However, when combined to a "self-compassion composite", the positive SCS subscales significantly moderated the relationship between "self-coldness" and depressive symptoms in the general population. This speaks for self-compassion having the potential to buffer self-coldness related to depression--providing an argument for interventions that foster self-caring, kind, and forgiving attitudes towards oneself.

  12. Gender Differences in Depressive Symptom Profile: Results from Nationwide General Population Surveys in Korea.

    PubMed

    Kim, Ji-Hyun; Cho, Maeng Je; Hong, Jin Pyo; Bae, Jae Nam; Cho, Seong-Jin; Hahm, Bong-Jin; Lee, Dong-Woo; Park, Jong-Ik; Lee, Jun-Young; Jeon, Hong Jin; Chang, Sung Man

    2015-11-01

    This study investigated gender differences in symptom profiles of major depressive disorder (MDD) in the Korean general population. Data were pooled from the series of nationwide Korean Epidemiologic Catchment Area surveys conducted in 2001, 2006 and 2011, respectively. Of the 18,807 participants, 507 (397 women and 110 men) were diagnosed with MDD within the prior 12 months. In agreement with previous studies, women with MDD appeared to be more vulnerable to experiencing atypical depressive episodes defined as depression with two or more symptoms of fatigue, increased appetite and hypersomnia (P < 0.001). In terms of individual symptoms, female gender was significantly related with higher prevalence of fatigue (P = 0.008), hypersomnia (P = 0.001), noticeable psychomotor retardation (P = 0.029) and suicidal attempts (P = 0.016) with adjustment for birth cohort effect, partner status, and employment status. In the same analysis, men with MDD appeared more vulnerable to decreased libido than women (P = 0.009). This is the first report to demonstrate gender differences in symptomatology of MDD in the general Korean population, and the results are comparable to previous investigations from western societies. Assumingly, the intercultural similarity in female preponderance to atypical depression might reflect the common biological construct underlying the gender difference in mechanism of MDD. In clinical settings, gender differences of MDD should be carefully considered, because these features could be related with treatment response and drug side effects.

  13. Revictimization of Violence Suffered by Those Diagnosed with Alcohol Dependence in the General Population

    PubMed Central

    Quintana, M. I.; Bressan, R. A.; Mello, M. F.; Andreoli, S. B.

    2015-01-01

    Objective. To verify the association between violence and alcohol dependence syndrome in sample populations. Method. Population-wide survey with multistage probabilistic sample. 3,744 individuals of both genders, aged from 15 to 75 years, were interviewed from the cities of São Paulo and Rio de Janeiro using the Composite International Diagnostic Interview (CIDI 2.1). Results. In both cities, alcohol dependence was associated with the male gender, having suffered violence related to criminality, and having suffered familial violence. In both cities, urban violence, in more than 50% of cases, and familial violence, in more than 90% of cases, preceded alcohol dependence. The reoccurrence of traumatic events occurred in more than half of individuals dependent on alcohol. In São Paulo, having been diagnosed with PTSD is associated with violence revictimization (P = 0.014; Odds = 3.33). Conclusion. Alcohol dependence syndrome is complexly related to urban and familial violence in the general population. Violence frequently precedes alcoholism, but this relationship is dependent on residence and traumatic events. This vicious cycle contributes to perpetuating the high rates of alcoholism and violence in the cities. Politicians ordering the reduction of violence in the large metropolises can, potentially, reduce alcoholism and contribute to the break of this cycle. PMID:26000304

  14. Why Einstein did not believe that general relativity geometrizes gravity

    NASA Astrophysics Data System (ADS)

    Lehmkuhl, Dennis

    2014-05-01

    I argue that, contrary to folklore, Einstein never really cared for geometrizing the gravitational or (subsequently) the electromagnetic field; indeed, he thought that the very statement that General Relativity geometrizes gravity "is not saying anything at all". Instead, I shall show that Einstein saw the "unification" of inertia and gravity as one of the major achievements of General Relativity. Interestingly, Einstein did not locate this unification in the field equations but in his interpretation of the geodesic equation, the law of motion of test particles.

  15. Canonical quantization of general relativity in discrete space-times.

    PubMed

    Gambini, Rodolfo; Pullin, Jorge

    2003-01-17

    It has long been recognized that lattice gauge theory formulations, when applied to general relativity, conflict with the invariance of the theory under diffeomorphisms. We analyze discrete lattice general relativity and develop a canonical formalism that allows one to treat constrained theories in Lorentzian signature space-times. The presence of the lattice introduces a "dynamical gauge" fixing that makes the quantization of the theories conceptually clear, albeit computationally involved. The problem of a consistent algebra of constraints is automatically solved in our approach. The approach works successfully in other field theories as well, including topological theories. A simple cosmological application exhibits quantum elimination of the singularity at the big bang.

  16. Canonical quantization of general relativity in discrete space-times.

    PubMed

    Gambini, Rodolfo; Pullin, Jorge

    2003-01-17

    It has long been recognized that lattice gauge theory formulations, when applied to general relativity, conflict with the invariance of the theory under diffeomorphisms. We analyze discrete lattice general relativity and develop a canonical formalism that allows one to treat constrained theories in Lorentzian signature space-times. The presence of the lattice introduces a "dynamical gauge" fixing that makes the quantization of the theories conceptually clear, albeit computationally involved. The problem of a consistent algebra of constraints is automatically solved in our approach. The approach works successfully in other field theories as well, including topological theories. A simple cosmological application exhibits quantum elimination of the singularity at the big bang. PMID:12570532

  17. Equations of motion in general relativity and quantum mechanics

    NASA Astrophysics Data System (ADS)

    O'Hara, Paul

    2011-12-01

    In a previous article a relationship was established between the linearized metrics of General Relativity associated with geodesics and the Dirac Equation of quantum mechanics. In this paper the extension of that result to arbitrary curves is investigated. A generalized Dirac equation is derived and shown to be related to the Lie derivative of the momentum along the curve. In addition,the equations of motion are derived from the Hamilton-Jacobi equation associated with the metric and the wave equation associated with the Hamiltonian is then shown not to commute with the Dirac operator. Finally, the Maxwell-Boltzmann distribution is shown to be a consequence of geodesic motion.

  18. Kerr black holes are not unique to general relativity.

    PubMed

    Psaltis, Dimitrios; Perrodin, Delphine; Dienes, Keith R; Mocioiu, Irina

    2008-03-01

    Considerable attention has recently focused on gravity theories obtained by extending general relativity with additional scalar, vector, or tensor degrees of freedom. In this Letter, we show that the black-hole solutions of these theories are essentially indistinguishable from those of general relativity. Thus, we conclude that a potential observational verification of the Kerr metric around an astrophysical black hole cannot, in and of itself, be used to distinguish between these theories. On the other hand, it remains true that detection of deviations from the Kerr metric will signify the need for a major change in our understanding of gravitational physics.

  19. General population and HIV prevention: from risk to action.

    PubMed

    Paicheler, G

    1999-11-01

    Since knowledge about AIDS transmission now appears to be very good, many observers are surprised that more people do not practice behavior, like safer sex, designed to minimize risk of contracting the disease. Still, previous studies have not shown that there is a direct link between knowledge and behavior. New models, based on people's concrete experiences, are therefore needed. The goal of this qualitative research, based on 61 in-depth interviews conducted in France, is to describe how people understand the threat of AIDS and how they face the risk of transmission in their sex lives. In order to understand preventive actions, we must study how information is interpreted and how knowledge is integrated, so that people perceive general or personal risk. We must also specify the way in which people distinguish between aspects of risk perception and vulnerability; feelings of personal control, constructed on the basis of social experiences; characteristics of situations; and finally, the dynamics of action. The proposed risk management model accounts for these diverse factors in elucidating the great diversity of actions reported. This dynamic, non-linear model is designed to capture both the impact of perceptive and cognitive elements on action and vice versa.

  20. Cosmological tests of general relativity with future tomographic surveys.

    PubMed

    Zhao, Gong-Bo; Pogosian, Levon; Silvestri, Alessandra; Zylberberg, Joel

    2009-12-11

    Future weak lensing surveys will map the evolution of matter perturbations and gravitational potentials, yielding a new test of general relativity on cosmic scales. They will probe the relations between matter overdensities, local curvature, and the Newtonian potential. These relations can be modified in alternative gravity theories or by the effects of massive neutrinos or exotic dark energy fluids. We introduce two functions of time and scale which account for any such modifications in the linear regime. We use a principal component analysis to find the eigenmodes of these functions that cosmological data will constrain. The number of constrained modes gives a model-independent forecast of how many parameters describing deviations from general relativity could be constrained, along with w(z). The modes' scale and time dependence tell us which theoretical models will be better tested.

  1. General relativity at 75: how right was einstein?

    PubMed

    Will, C M

    1990-11-01

    The status of experimental tests of general relativity is reviewed on the occasion of its 75th anniversary. Einstein's equivalence principle is well supported by experiments such as the Eötvös experiment, tests of special relativity, and the gravitational redshift experiment. Tests of general relativity have reached high precision, including the light deflection and the perihelion advance of Mercury, proposed by Einstein 75 years ago, and new tests such as the Shapiro time delay and the Nordtvedt effect in lunar motion. Gravitational wave damping has been detected to an accuracy of 1 percent on the basis of measurements of the binary pulsar. The status of the "fifth force" is discussed, along with the frontiers of experimental relativity, including proposals for testing relativistic gravity with advanced technology and spacecraft.

  2. Doppler frequency in interplanetary radar and general relativity

    NASA Technical Reports Server (NTRS)

    Mcvittie, G. C.

    1972-01-01

    The change of frequency of an interplanetary radar signal sent from the earth to another planet or to a space probe is worked out according to general relativity. The Schwarzschild spacetime is employed and its null geodesics control the motion of the signals. Exact Doppler frequency formulas are derived for one-way and two-way radar in terms of an arbitrary Schwarzschild radial coordinate. A reduction to the special relativity case is used to interpret the formulas in terms of the relative radial velocity of emitter and target. The general relativity corrections are worked out approximately for each of three possible Schwarzschild radial coordinates, and a numerical example is given. The amount of the correction is different according as one or the other of the Schwarzschild coordinates is identified with the radius vector deduced from classical celestial mechanics. The identification problem is discussed.

  3. The relationship of neuroticism and extraversion to symptoms of anxiety and depression in the general population.

    PubMed

    Jylhä, Pekka; Isometsä, Erkki

    2006-01-01

    Few studies have investigated the relationship of the personality dimensions of neuroticism and extraversion to the symptoms of depression and anxiety in the general population. A random general population sample (ages 20-70 years), from two Finnish cities was surveyed with the Eysenck Personality Inventory (EPI), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI). In addition, questions regarding diagnosed lifetime mental disorders, health care use for psychiatric reasons in the past 12 months, and history of mental disorders in first-degree relatives were posed. Among the 441 subjects who participated, neuroticism correlated strongly with symptoms of depression (r(s)=.71, P<.001) and anxiety (r(s)=.69, P<.001), and somewhat with self-reported lifetime mental disorder (r(s)=.30, P<.001) and health care use for psychiatric reasons in the past 12 months (r(s)=.24, P<.001). Extraversion correlated negatively with symptoms of depression (r(s)=-.47, P<.001), anxiety (r(s)=-.36, P<.001), self-reported lifetime mental disorder (r(s)=-.17, P<.001), and health care use for psychiatric reasons in the past 12 months (r(s)=-.14, P=.004). In multiple regression models, even after adjusting for gender, age, and education, BDI scores were significantly associated with neuroticism, extraversion, and age, whereas BAI scores were associated only with neuroticism. Neuroticism is strongly associated with depressive and anxiety symptoms, and intraversion is moderately associated with depressive symptoms in the urban general population. The relationship of these personality dimensions to both self-reported lifetime mental disorders and use of health services for psychiatric reasons strengthens the clinical validity of these personality dimensions.

  4. Unimodular metagravity vs. general relativity with a scalar field

    SciTech Connect

    Pirogov, Yu. F.

    2010-01-15

    The unimodular metagravity, with the graviscalar as a dark matter, is compared with General Relativity (GR) in the presence of a scalar field. The effect of the graviscalar on the static spherically symmetric metric is studied. An exact limit solution representing a new cosmic object, the (harmonic) graviscalar black hole, is given. The relation with the black hole in the environment of a scalar field in GR is discussed.

  5. Non-inertial Frames in Special and General Relativity

    NASA Astrophysics Data System (ADS)

    Lusanna, Luca

    A theory of global non-inertial frames in special relativity is developed by taking into account relativistic metrology and by avoiding the coordinate singularities of the rotating disk and of Fermi coordinates. Then this theory is used in general relativity for the treatment of globally hyperbolic, asymptotically Minkowskian space-times solution of Einstein's equations. Also some comments on the problem of dark matter, connecting it to the relativistic metrology used in astrophysics, are made.

  6. BOOK REVIEW: Partial Differential Equations in General Relativity

    NASA Astrophysics Data System (ADS)

    Halburd, Rodney G.

    2008-11-01

    Although many books on general relativity contain an overview of the relevant background material from differential geometry, very little attention is usually paid to background material from the theory of differential equations. This is understandable in a first course on relativity but it often limits the kinds of problems that can be studied rigorously. Einstein's field equations lie at the heart of general relativity. They are a system of partial differential equations (PDEs) relating the curvature of spacetime to properties of matter. A central part of most problems in general relativity is to extract information about solutions of these equations. Most standard texts achieve this by studying exact solutions or numerical and analytical approximations. In the book under review, Alan Rendall emphasises the role of rigorous qualitative methods in general relativity. There has long been a need for such a book, giving a broad overview of the relevant background from the theory of partial differential equations, and not just from differential geometry. It should be noted that the book also covers the basic theory of ordinary differential equations. Although there are many good books on the rigorous theory of PDEs, methods related to the Einstein equations deserve special attention, not only because of the complexity and importance of these equations, but because these equations do not fit into any of the standard classes of equations (elliptic, parabolic, hyperbolic) that one typically encounters in a course on PDEs. Even specifying exactly what ones means by a Cauchy problem in general relativity requires considerable care. The main problem here is that the manifold on which the solution is defined is determined by the solution itself. This means that one does not simply define data on a submanifold. Rendall's book gives a good overview of applications and results from the qualitative theory of PDEs to general relativity. It would be impossible to give detailed

  7. Generalized entropies and logarithms and their duality relations

    PubMed Central

    Hanel, Rudolf; Thurner, Stefan; Gell-Mann, Murray

    2012-01-01

    For statistical systems that violate one of the four Shannon–Khinchin axioms, entropy takes a more general form than the Boltzmann–Gibbs entropy. The framework of superstatistics allows one to formulate a maximum entropy principle with these generalized entropies, making them useful for understanding distribution functions of non-Markovian or nonergodic complex systems. For such systems where the composability axiom is violated there exist only two ways to implement the maximum entropy principle, one using escort probabilities, the other not. The two ways are connected through a duality. Here we show that this duality fixes a unique escort probability, which allows us to derive a complete theory of the generalized logarithms that naturally arise from the violation of this axiom. We then show how the functional forms of these generalized logarithms are related to the asymptotic scaling behavior of the entropy. PMID:23129618

  8. Generalized entropies and logarithms and their duality relations.

    PubMed

    Hanel, Rudolf; Thurner, Stefan; Gell-Mann, Murray

    2012-11-20

    For statistical systems that violate one of the four Shannon-Khinchin axioms, entropy takes a more general form than the Boltzmann-Gibbs entropy. The framework of superstatistics allows one to formulate a maximum entropy principle with these generalized entropies, making them useful for understanding distribution functions of non-Markovian or nonergodic complex systems. For such systems where the composability axiom is violated there exist only two ways to implement the maximum entropy principle, one using escort probabilities, the other not. The two ways are connected through a duality. Here we show that this duality fixes a unique escort probability, which allows us to derive a complete theory of the generalized logarithms that naturally arise from the violation of this axiom. We then show how the functional forms of these generalized logarithms are related to the asymptotic scaling behavior of the entropy.

  9. Related General-Vocabulary Knowledge Transfers to Learning Technical Terms

    ERIC Educational Resources Information Center

    Balch, William R.

    2015-01-01

    In a classroom experiment during the first week of an introductory psychology course, randomly assigned students received a pretest and then a brief training on the definitions of general-vocabulary words either related (e.g., "facilitation") or unrelated (e.g., "rendition") to 16 technical terms (e.g., "social…

  10. Testing general relativity: from local to cosmological scales.

    PubMed

    Uzan, Jean-Philippe

    2011-12-28

    I summarize various tests of general relativity on astrophysical scales, based on the large-scale structure of the universe but also on other systems, in particular the constants of physics. I emphasize the importance of hypotheses on the geometric structures of our universe while performing such tests and discuss their complementarity as well as their possible extensions.

  11. Probing Students' Understanding of Some Conceptual Themes in General Relativity

    ERIC Educational Resources Information Center

    Bandyopadhyay, Atanu; Kumar, Arvind

    2010-01-01

    This work is an attempt to see how physics undergraduates view the basic ideas of general relativity when they are exposed to the topic in a standard introductory course. Since the subject is conceptually and technically difficult, we adopted a "case studies" approach, focusing in depth on about six students who had just finished a one semester…

  12. Spinning fluids in general relativity. II - Self-consistent formulation

    NASA Technical Reports Server (NTRS)

    Ray, John R.; Smalley, Larry, L.; Krisch, Jean P.

    1987-01-01

    Methods used earlier to derive the equations of motion for a spinning fluid in the Einstein-Cartan theory are specialized to the case of general relativity. The main idea is to include the spin as a thermodynamic variable in the theory.

  13. Factors Affecting the Relative Efficiency of General Acid Catalysis

    ERIC Educational Resources Information Center

    Kwan, Eugene E.

    2005-01-01

    A simple framework for evaluating experimental kinetic data to provide support for Specific Acid Catalysis (SAC) and General Acid Catalysis (GAC) is described based on the factors affecting their relative efficiency. Observations reveal that increasing the SAC-to-GAC rate constant ratio reduces the effective pH range for GAC.

  14. Influence of population and general practice characteristics on prescribing of minor tranquilisers in primary care

    PubMed Central

    Wagner, Andrew C.; Hann, Mark; Ashcroft, Daren M.

    2010-01-01

    Prevalence of generalised anxiety disorders is widespread in Great Britain. Previous small-scale research has shown variations in minor tranquiliser prescribing, identifying several potential predictors of prescribing volume. Objective: This study aimed to investigate the relationship between general practice minor tranquiliser prescribing rates and practice population and general practice characteristics for all general practices in England. Methods: Multiple regression analysis of minor tranquiliser prescribing volumes during 2004/2005 for 8,291 English general practices with general practice and population variables obtained from the General Medical Services (GMS) statistics, Quality and Outcomes Framework (QOF), 2001 Census and 2004 Index of Multiple Deprivation (IMD). Results: The highest rates of minor tranquiliser prescribing were in areas with the greatest local deprivation while general practices situated in areas with larger proportions of residents of black ethnic origin had lower rates of prescribing. Other predictors of increased prescribing were general practices with older general practitioners and general practices with older registered practice populations. Conclusion: Our findings show that there is wide variation of minor tranquilisers prescribing across England which has implications regarding access to treatment and inequity of service provision. Future research should determine the barriers to equitable prescribing amongst general practices serving larger populations of black ethnic origin. PMID:25126140

  15. Confidence intervals for population allele frequencies: the general case of sampling from a finite diploid population of any size.

    PubMed

    Fung, Tak; Keenan, Kevin

    2014-01-01

    The estimation of population allele frequencies using sample data forms a central component of studies in population genetics. These estimates can be used to test hypotheses on the evolutionary processes governing changes in genetic variation among populations. However, existing studies frequently do not account for sampling uncertainty in these estimates, thus compromising their utility. Incorporation of this uncertainty has been hindered by the lack of a method for constructing confidence intervals containing the population allele frequencies, for the general case of sampling from a finite diploid population of any size. In this study, we address this important knowledge gap by presenting a rigorous mathematical method to construct such confidence intervals. For a range of scenarios, the method is used to demonstrate that for a particular allele, in order to obtain accurate estimates within 0.05 of the population allele frequency with high probability (> or = 95%), a sample size of > 30 is often required. This analysis is augmented by an application of the method to empirical sample allele frequency data for two populations of the checkerspot butterfly (Melitaea cinxia L.), occupying meadows in Finland. For each population, the method is used to derive > or = 98.3% confidence intervals for the population frequencies of three alleles. These intervals are then used to construct two joint > or = 95% confidence regions, one for the set of three frequencies for each population. These regions are then used to derive a > or = 95%% confidence interval for Jost's D, a measure of genetic differentiation between the two populations. Overall, the results demonstrate the practical utility of the method with respect to informing sampling design and accounting for sampling uncertainty in studies of population genetics, important for scientific hypothesis-testing and also for risk-based natural resource management. PMID:24465792

  16. Comparison of Musculoskeletal Disorder Health Claims Between Construction Floor Layers and a General Working Population

    PubMed Central

    Dale, Ann Marie; Ryan, Daniel; Welch, Laura; Olsen, Margaret A.; Buchholz, Bryan; Evanoff, Bradley

    2014-01-01

    Objectives Compare rates of medical insurance claims for musculoskeletal disorders (MSD) between workers in a construction trade and a general worker population to determine if higher physical exposures in construction lead to higher rates of claims on personal medical insurance. Methods Health insurance claims between 2006 and 2010 from floor layers were frequency matched by age, gender, eligibility time, and geographic location to claims from insured workers in general industry obtained from MarketScan. We extracted MSD claims and dates of service from six regions of the body: neck, low back, knee, lower extremity, shoulder, and distal arm, and evaluated differences in claim rates. Results Fifty-one percent of floor layers (n=1,475) experienced musculoskeletal claims compared to 39% of MarketScan members (p<0.001). Claim rates were higher for floor layers across all body regions with nearly double the rate ratios for the knee and neck regions (RR: 2.10 and 2.07). The excess risk was greatest for the neck and low back regions; younger workers had disproportionately higher rates in the knee, neck, low back, and distal arm. A larger proportion of floor layers (22%) filed MSD claims in more than one body region compared to general workers (10%; p<0.001). Conclusions Floor layers have markedly higher rates of MSD claims compared to a general worker population, suggesting shifting of medical costs for work-related MSD to personal health insurance. The occurrence of disorders in multiple body regions and among the youngest workers highlights the need for improved work methods and tools for construction workers. PMID:25224720

  17. Einstein's First Steps Toward General Relativity: Gedanken Experiments and Axiomatics

    NASA Astrophysics Data System (ADS)

    Miller, A. I.

    1999-03-01

    Albert Einstein's 1907 Jahrbuch paper is an extraordinary document because it contains his first steps toward generalizing the 1905 relativity theory to include gravitation. Ignoring the apparent experimental disconfirmation of the 1905 relativity theory and his unsuccessful attempts to generalize the mass-energy equivalence, Einstein boldly raises the mass-energy equivalence to an axiom, invokes equality between gravitational and inertial masses, and then postulates the equivalence between a uniform gravitational field and an oppositely directed constant acceleration, the equivalence principle. How did this come about? What is at issue is scientific creativity. This necessitates broadening historical analysis to include aspects of cognitive science such as the role of visual imagery in Einstein's thinking, and the relation between conscious and unconscious modes of thought in problem solving. This method reveals the catalysts that sparked a Gedanken experiment that occurred to Einstein while working on the Jahrbuch paper. A mental model is presented to further explore Einstein's profound scientific discovery.

  18. Learning-related shifts in generalization gradients for complex sounds.

    PubMed

    Wisniewski, Matthew G; Church, Barbara A; Mercado, Eduardo

    2009-11-01

    Learning to discriminate stimuli can alter how one distinguishes related stimuli. For instance, training an individual to differentiate between two stimuli along a single dimension can alter how that individual generalizes learned responses. In this study, we examined the persistence of shifts in generalization gradients after training with sounds. University students were trained to differentiate two sounds that varied along a complex acoustic dimension. The students were subsequently tested on their ability to recognize a sound that they had experienced during training when it was presented among several novel sounds varying along this same dimension. Peak shift was observed in Experiment 1, in which generalization tests immediately followed training, and in Experiment 2, in which the tests were delayed by 24 h. These findings further support the universality of generalization processes across species, modalities, and levels of stimulus complexity. They also raise new questions about the mechanisms underlying learning-related shifts in generalization gradients. The sound stimuli from this study are available as .wav files from http://lb.psychonomic-journals.org/content/supplemental.

  19. BOOK REVIEW: Partial Differential Equations in General Relativity

    NASA Astrophysics Data System (ADS)

    Choquet-Bruhat, Yvonne

    2008-09-01

    General relativity is a physical theory basic in the modeling of the universe at the large and small scales. Its mathematical formulation, the Einstein partial differential equations, are geometrically simple, but intricate for the analyst, involving both hyperbolic and elliptic PDE, with local and global problems. Many problems remain open though remarkable progress has been made recently towards their solutions. Alan Rendall's book states, in a down-to-earth form, fundamental results used to solve different types of equations. In each case he gives applications to special models as well as to general properties of Einsteinian spacetimes. A chapter on ODE contains, in particular, a detailed discussion of Bianchi spacetimes. A chapter entitled 'Elliptic systems' treats the Einstein constraints. A chapter entitled 'Hyperbolic systems' is followed by a chapter on the Cauchy problem and a chapter 'Global results' which contains recently proved theorems. A chapter is dedicated to the Einstein Vlasov system, of which the author is a specialist. On the whole, the book surveys, in a concise though precise way, many essential results of recent interest in mathematical general relativity, and it is very clearly written. Each chapter is followed by an up to date bibliography. In conclusion, this book will be a valuable asset to relativists who wish to learn clearly-stated mathematical results and to mathematicians who want to penetrate into the subtleties of general relativity, as a mathematical and physical theory.

  20. Evidence for a General ADHD Factor from a Longitudinal General School Population Study

    ERIC Educational Resources Information Center

    Normand, Sebastien; Flora, David B.; Toplak, Maggie E.; Tannock, Rosemary

    2012-01-01

    Recent factor analytic studies in Attention-Deficit/Hyperactivity Disorder (ADHD) have shown that hierarchical models provide a better fit of ADHD symptoms than correlated models. A hierarchical model includes a general ADHD factor and specific factors for inattention, and hyperactivity/impulsivity. The aim of this 12-month longitudinal study was…

  1. An interesting consequence of the general principle of relativity

    NASA Astrophysics Data System (ADS)

    Grøn, Øyvind; Jemterud, Torkild

    2016-04-01

    We show that Einstein's general theory of relativity, together with the assumption that the principle of relativity encompasses rotational motion, predicts that in a flat Friedmann-Lemaitre-Robertson-Walker (FLRW) universe model with dust and Lorentz Invariant Vacuum Energy (LIVE), the density parameter of vacuum energy must have the value Ω_{Λ 0}=0.737. The physical mechanism connecting the relativity of rotational motion with the energy density of dark energy is the inertial dragging effect. The predicted value is necessary in order to have perfect inertial dragging, which is required for rotational motion to be relative. If one accepts that due to the impossibility of defining motion for a single particle in an otherwise empty universe, the universe must be constructed so that all types of motion are relative, then this solves the so-called cosmological constant problem.

  2. Dispersal patterns of red foxes relative to population density

    USGS Publications Warehouse

    Allen, Stephen H.; Sargeant, Alan B.

    1993-01-01

    Factors affecting red fox (Vulpes vulpes) dispersal patterns are poorly understood but warranted investigation because of the role of dispersal in rebuilding depleted populations and transmission of diseases. We examined dispersal patterns of red foxes in North Dakota based on recoveries of 363 of 854 foxes tagged as pups and relative to fox density. Foxes were recovered up to 8.6 years after tagging; 79% were trapped or shot. Straight-line distances between tagging and recovery locations ranged from 0 to 302 km. Mean recovery distances increased with age and were greater for males than females, but longest individual recovery distances were by females. Dispersal distances were not related to population density for males (P = 0.36) or females (P = 0.96). The proportion of males recovered that dispersed was inversely related to population density (r = -0.94; n = 5; P = 0.02), but not the proportion of females (r = -0.49; n = 5; P = 0.40). Dispersal directions were not uniform for either males (P = 0.003) or females (P = 0.006); littermates tended to disperse in similar directions (P = 0.09). A 4-lane interstate highway altered dispersal directions (P = 0.001). Dispersal is a strong innate behavior of red foxes (especially males) that results in many individuals of both sexes traveling far from natal areas. Because dispersal distance was unaffected by fox density, populations can be rebuilt and diseases transmitted long distances regardless of fox abundance.

  3. Sign Language Users' Education and Employment Levels: Keeping Pace with Changes in the General Australian Population?

    ERIC Educational Resources Information Center

    Willoughby, Louisa

    2011-01-01

    This article draws on data from the 2006 Australian census to explore the education and employment outcomes of sign languages users living in Victoria, Australia, and to compare them with outcomes reported in the general population. Census data have the advantage of sampling the entire population on the one night, avoiding problems of population…

  4. Assessment of occupational exposures in a general population: comparison of different methods

    PubMed Central

    Tielemans, E.; Heederik, D.; Burdorf, A.; Vermeulen, R.; Veulemans, H.; Kromhout, H.; Hartog, K.

    1999-01-01

    OBJECTIVES: To evaluate the relative merits of job specific questionnaires and various alternative assessment methods of occupational exposures often used in general population studies. METHODS: Subjects were participants in a hospital based case-control study of risk factors for male infertility. Estimates of exposure to organic solvents and chromium, based on job specific questionnaires, generic questionnaires, self reports of exposure, an external job exposure matrix (JEM), and a population specific JEM were compared with passive diffuse dosimeter results and measurements in urine. Urine samples from the end of the shift were analysed for metabolites of toluene, xylene, several glycol ethers, trichloroethylene, and chromium. Passive dosimeter date, metabolites of specific solvents, and urinary chromium concentrations were available for 89, 267, and 156 subjects, respectively. The alternative methods and measurements in urine were compared by means of the Cohen's kappa statistic and by computing the positive predictive value, sensitivity, and specificity of the alternative methods against measurements in urine. RESULTS: Passive dosimeter results indicated that exposure classifications with job specific questionnaire information could discriminate between high and low exposures. The kappa coefficients were < 0.4, so agreement between the various methods and measurements in urine was poor. Sensitivity of the methods ranged from 0.21 to 0.85, whereas specificity ranged from 0.34 to 0.94. Positive predictive values ranged from 0.19 to 0.58, with the highest values for job specific questionnaires. CONCLUSIONS: The results indicate that the implementation of job specific questionnaires in a general population study might be worth the extra expense it entails, bearing in mind the paramount importance of avoiding false positive exposure estimates when exposure prevalence is low.   PMID:10448321

  5. Macrostate equivalence of two general ensembles and specific relative entropies

    NASA Astrophysics Data System (ADS)

    Mori, Takashi

    2016-08-01

    The two criteria of ensemble equivalence, i.e., macrostate equivalence and measure equivalence, are investigated for a general pair of states. Macrostate equivalence implies the two ensembles are indistinguishable by the measurement of macroscopic quantities obeying the large-deviation principle, and measure equivalence means that the specific relative entropy of these two states vanishes in the thermodynamic limit. It is shown that measure equivalence implies a macrostate equivalence for a general pair of states by deriving an inequality connecting the large-deviation rate functions to the specific relative Renyi entropies. The result is applicable to both quantum and classical systems. As applications, a sufficient condition for thermalization, the time scale of quantum dynamics of macrovariables, and the second law with strict irreversibility in a quantum quench are discussed.

  6. General Theory of Relativity: Will It Survive the Next Decade?

    NASA Technical Reports Server (NTRS)

    Bertolami, Orfeu; Paramos, Jorge; Turyshev, Slava G.

    2006-01-01

    The nature of gravity is fundamental to our understanding of our own solar system, the galaxy and the structure and evolution of the Universe. Einstein's general theory of relativity is the standard model that is used for almost ninety years to describe gravitational phenomena on these various scales. We review the foundations of general relativity, discuss the recent progress in the tests of relativistic gravity, and present motivations for high-accuracy gravitational experiments in space. We also summarize the science objectives and technology needs for the laboratory experiments in space with laboratory being the entire solar system. We discuss the advances in our understanding of fundamental physics anticipated in the near future and evaluate discovery potential for the recently proposed gravitational experiments.

  7. Testing General Relativity with the Shadow Size of Sgr A(*).

    PubMed

    Johannsen, Tim; Broderick, Avery E; Plewa, Philipp M; Chatzopoulos, Sotiris; Doeleman, Sheperd S; Eisenhauer, Frank; Fish, Vincent L; Genzel, Reinhard; Gerhard, Ortwin; Johnson, Michael D

    2016-01-22

    In general relativity, the angular radius of the shadow of a black hole is primarily determined by its mass-to-distance ratio and depends only weakly on its spin and inclination. If general relativity is violated, however, the shadow size may also depend strongly on parametric deviations from the Kerr metric. Based on a reconstructed image of Sagittarius A^{*} (Sgr A^{*}) from a simulated one-day observing run of a seven-station Event Horizon Telescope (EHT) array, we employ a Markov chain Monte Carlo algorithm to demonstrate that such an observation can measure the angular radius of the shadow of Sgr A^{*} with an uncertainty of ∼1.5  μas (6%). We show that existing mass and distance measurements can be improved significantly when combined with upcoming EHT measurements of the shadow size and that tight constraints on potential deviations from the Kerr metric can be obtained.

  8. Macrostate equivalence of two general ensembles and specific relative entropies.

    PubMed

    Mori, Takashi

    2016-08-01

    The two criteria of ensemble equivalence, i.e., macrostate equivalence and measure equivalence, are investigated for a general pair of states. Macrostate equivalence implies the two ensembles are indistinguishable by the measurement of macroscopic quantities obeying the large-deviation principle, and measure equivalence means that the specific relative entropy of these two states vanishes in the thermodynamic limit. It is shown that measure equivalence implies a macrostate equivalence for a general pair of states by deriving an inequality connecting the large-deviation rate functions to the specific relative Renyi entropies. The result is applicable to both quantum and classical systems. As applications, a sufficient condition for thermalization, the time scale of quantum dynamics of macrovariables, and the second law with strict irreversibility in a quantum quench are discussed. PMID:27627225

  9. A century of general relativity: astrophysics and cosmology.

    PubMed

    Blandford, R D

    2015-03-01

    One hundred years after its birth, general relativity has become a highly successful physical theory in the sense that it has passed a large number of experimental and observational tests and finds extensive application to a wide variety of cosmic phenomena. It remains an active area of research as new tests are on the way, epitomized by the exciting prospect of detecting gravitational waves from merging black holes. General relativity is the essential foundation of the standard model of cosmology and underlies our description of the black holes and neutron stars that are ultimately responsible for the most powerful and dramatic cosmic sources. Its interface with physics on the smallest and largest scales will continue to provide fertile areas of investigation in its next century.

  10. Testing General Relativity with the Shadow Size of Sgr A(*).

    PubMed

    Johannsen, Tim; Broderick, Avery E; Plewa, Philipp M; Chatzopoulos, Sotiris; Doeleman, Sheperd S; Eisenhauer, Frank; Fish, Vincent L; Genzel, Reinhard; Gerhard, Ortwin; Johnson, Michael D

    2016-01-22

    In general relativity, the angular radius of the shadow of a black hole is primarily determined by its mass-to-distance ratio and depends only weakly on its spin and inclination. If general relativity is violated, however, the shadow size may also depend strongly on parametric deviations from the Kerr metric. Based on a reconstructed image of Sagittarius A^{*} (Sgr A^{*}) from a simulated one-day observing run of a seven-station Event Horizon Telescope (EHT) array, we employ a Markov chain Monte Carlo algorithm to demonstrate that such an observation can measure the angular radius of the shadow of Sgr A^{*} with an uncertainty of ∼1.5  μas (6%). We show that existing mass and distance measurements can be improved significantly when combined with upcoming EHT measurements of the shadow size and that tight constraints on potential deviations from the Kerr metric can be obtained. PMID:26849580

  11. Towards the quasi-localization of canonical general relativity

    NASA Astrophysics Data System (ADS)

    Szabados, László B.

    2009-06-01

    A general framework for a systematic quasi-localization of canonical general relativity and a new ingredient, the requirement of the gauge invariance of the boundary terms appearing in the calculation of Poisson brackets, are given. As a consequence of this it is shown, in particular, that the generator vector fields (built from the lapse and shift) of the quasi-local quantities must be divergence free with respect to a Sen-type connection, and the volume form induced from the spatial metric on the boundary surface must be fixed. Talk given at the Conference on Recent Results in Mathematical Relativity, The Erwin Schrödinger Institute, Vienna, 20-21 August 2008, and dedicated to Bobby Beig on the occasion of his 60th birthday.

  12. Remarks on Definitions of Perturbation in General Relativity

    NASA Astrophysics Data System (ADS)

    He, Ping

    2009-02-01

    There are two kinds of definitions of perturbation of physical quantities in the framework of general relativity: one is direct, the other is geometrical. Correspondingly, there are two types of gauge transformation related with these two definitions. The passive approach is based on the property of general covariance, and the active one is through the action of Lie-derivative. Although under a proper coordinate choice, the two approaches seem to agree with each other, they are different in nature. The geometrical definition of relativistic perturbation and the active approach for gauge transformation are more rigorous in mathematics and less confusing in physical explanation. The direct definition, however, seems to be plagued with difficulties in physical meaning, and the passive approach is more awkward to use, especially for high-order gauge transformations.

  13. A century of general relativity: Astrophysics and cosmology

    NASA Astrophysics Data System (ADS)

    Blandford, R. D.

    2015-03-01

    One hundred years after its birth, general relativity has become a highly successful physical theory in the sense that it has passed a large number of experimental and observational tests and finds extensive application to a wide variety of cosmic phenomena. It remains an active area of research as new tests are on the way, epitomized by the exciting prospect of detecting gravitational waves from merging black holes. General relativity is the essential foundation of the standard model of cosmology and underlies our description of the black holes and neutron stars that are ultimately responsible for the most powerful and dramatic cosmic sources. Its interface with physics on the smallest and largest scales will continue to provide fertile areas of investigation in its next century.

  14. A century of general relativity: astrophysics and cosmology.

    PubMed

    Blandford, R D

    2015-03-01

    One hundred years after its birth, general relativity has become a highly successful physical theory in the sense that it has passed a large number of experimental and observational tests and finds extensive application to a wide variety of cosmic phenomena. It remains an active area of research as new tests are on the way, epitomized by the exciting prospect of detecting gravitational waves from merging black holes. General relativity is the essential foundation of the standard model of cosmology and underlies our description of the black holes and neutron stars that are ultimately responsible for the most powerful and dramatic cosmic sources. Its interface with physics on the smallest and largest scales will continue to provide fertile areas of investigation in its next century. PMID:25745165

  15. Testing general relativity with laser accelerated electron beams

    SciTech Connect

    Gergely, L. A.; Harko, T.

    2012-07-09

    Electron accelerations of the order of 10{sup 21} g obtained by laser fields open up the possibility of experimentally testing one of the cornerstones of general relativity, the weak equivalence principle, which states that the local effects of a gravitational field are indistinguishable from those sensed by a properly accelerated observer in flat space-time. We illustrate how this can be done by solving the Einstein equations in vacuum and integrating the geodesic equations of motion for a uniformly accelerated particle.

  16. Sensor failure detection using generalized parity relations for flexible structures

    NASA Technical Reports Server (NTRS)

    Mercadal, Mathieu

    1989-01-01

    Analytical redundancy may be preferable to hardware redundancy in failure detection/isolation tasks for such large-scale systems as space structures. Generalized single-sensor parity relations are presently applied to this problem; they are noted to yield a very simple isolation logic, and their generation is found to be extremely rapid, even in the case of extremely complex systems, provided only that the eigenstructure of the system be known. Their implementation is, however, extremely sensitive to modeling errors and noise.

  17. The effects of general relativity on near-earth satellites

    NASA Technical Reports Server (NTRS)

    Ries, J. C.; Watkins, M. M.; Tapley, B. D.; Huang, C.

    1990-01-01

    Whether one uses a solar system barycentric frame or a geocentric frame when including the general theory of relativity in orbit determination for near-earth satellites, the results should be equivalent to some limiting accuracy. The purpose of this paper is to clarify the effects of relativity in each frame and to demonstrate their equivalence through the analysis of three years of laser tracking data taken on the Lageos satellite. It is demonstrated that the simpler formulation in the geocentric frame is adequate for the purpose of near-earth satellite orbit determination. A correction to the conventional barycentric equations of motion is shown to be required.

  18. Explanatory and illustrative visualization of special and general relativity.

    PubMed

    Weiskopf, Daniel; Borchers, Marc; Ertl, Thomas; Falk, Martin; Fechtig, Oliver; Frank, Regine; Grave, Frank; King, Andreas; Kraus, Ute; Müller, Thomas; Nollert, Hans-Peter; Rica Mendez, Isabel; Ruder, Hanns; Schafhitzel, Tobias; Schär, Sonja; Zahn, Corvin; Zatloukal, Michael

    2006-01-01

    This paper describes methods for explanatory and illustrative visualizations used to communicate aspects of Einstein's theories of special and general relativity, their geometric structure, and of the related fields of cosmology and astrophysics. Our illustrations target a general audience of laypersons interested in relativity. We discuss visualization strategies, motivated by physics education and the didactics of mathematics, and describe what kind of visualization methods have proven to be useful for different types of media, such as still images in popular science magazines, film contributions to TV shows, oral presentations, or interactive museum installations. Our primary approach is to adopt an egocentric point of view: The recipients of a visualization participate in a visually enriched thought experiment that allows them to experience or explore a relativistic scenario. In addition, we often combine egocentric visualizations with more abstract illustrations based on an outside view in order to provide several presentations of the same phenomenon. Although our visualization tools often build upon existing methods and implementations, the underlying techniques have been improved by several novel technical contributions like image-based special relativistic rendering on GPUs, special relativistic 4D ray tracing for accelerating scene objects, an extension of general relativistic ray tracing to manifolds described by multiple charts, GPU-based interactive visualization of gravitational light deflection, as well as planetary terrain rendering. The usefulness and effectiveness of our visualizations are demonstrated by reporting on experiences with, and feedback from, recipients of visualizations and collaborators. PMID:16805261

  19. Explanatory and illustrative visualization of special and general relativity.

    PubMed

    Weiskopf, Daniel; Borchers, Marc; Ertl, Thomas; Falk, Martin; Fechtig, Oliver; Frank, Regine; Grave, Frank; King, Andreas; Kraus, Ute; Müller, Thomas; Nollert, Hans-Peter; Rica Mendez, Isabel; Ruder, Hanns; Schafhitzel, Tobias; Schär, Sonja; Zahn, Corvin; Zatloukal, Michael

    2006-01-01

    This paper describes methods for explanatory and illustrative visualizations used to communicate aspects of Einstein's theories of special and general relativity, their geometric structure, and of the related fields of cosmology and astrophysics. Our illustrations target a general audience of laypersons interested in relativity. We discuss visualization strategies, motivated by physics education and the didactics of mathematics, and describe what kind of visualization methods have proven to be useful for different types of media, such as still images in popular science magazines, film contributions to TV shows, oral presentations, or interactive museum installations. Our primary approach is to adopt an egocentric point of view: The recipients of a visualization participate in a visually enriched thought experiment that allows them to experience or explore a relativistic scenario. In addition, we often combine egocentric visualizations with more abstract illustrations based on an outside view in order to provide several presentations of the same phenomenon. Although our visualization tools often build upon existing methods and implementations, the underlying techniques have been improved by several novel technical contributions like image-based special relativistic rendering on GPUs, special relativistic 4D ray tracing for accelerating scene objects, an extension of general relativistic ray tracing to manifolds described by multiple charts, GPU-based interactive visualization of gravitational light deflection, as well as planetary terrain rendering. The usefulness and effectiveness of our visualizations are demonstrated by reporting on experiences with, and feedback from, recipients of visualizations and collaborators.

  20. Constraints on a new post-general relativity cosmological parameter

    NASA Astrophysics Data System (ADS)

    Caldwell, Robert; Cooray, Asantha; Melchiorri, Alessandro

    2007-07-01

    A new cosmological variable is introduced to characterize the degree of departure from Einstein’s general relativity with a cosmological constant. The new parameter, ϖ, is the cosmological analog of γ, the parametrized post-Newtonian variable which measures the amount of spacetime curvature per unit mass. In the cosmological context, ϖ measures the difference between the Newtonian and longitudinal potentials in response to the same matter sources, as occurs in certain scalar-tensor theories of gravity. Equivalently, ϖ measures the scalar shear fluctuation in a dark-energy component. In the context of a vanilla, cosmological constant-dominated universe, a nonzero ϖ signals a departure from general relativity or a fluctuating cosmological constant. Using a phenomenological model for the time evolution ϖ=ϖ0ρDE/ρM which depends on the ratio of energy density in the cosmological constant to the matter density at each epoch, it is shown that the observed cosmic microwave background temperature anisotropies limit the overall normalization constant to be -0.4<ϖ0<0.1 at the 95% confidence level. Existing measurements of the cross-correlations of the cosmic microwave background with large-scale structure further limit ϖ0>-0.2 at the 95% CL. In the future, integrated Sachs-Wolfe and weak lensing measurements can more tightly constrain ϖ0, providing a valuable clue to the nature of dark energy and the validity of general relativity.

  1. Tests of general relativity from timing the double pulsar.

    PubMed

    Kramer, M; Stairs, I H; Manchester, R N; McLaughlin, M A; Lyne, A G; Ferdman, R D; Burgay, M; Lorimer, D R; Possenti, A; D'Amico, N; Sarkissian, J M; Hobbs, G B; Reynolds, J E; Freire, P C C; Camilo, F

    2006-10-01

    The double pulsar system PSR J0737-3039A/B is unique in that both neutron stars are detectable as radio pulsars. They are also known to have much higher mean orbital velocities and accelerations than those of other binary pulsars. The system is therefore a good candidate for testing Einstein's theory of general relativity and alternative theories of gravity in the strong-field regime. We report on precision timing observations taken over the 2.5 years since its discovery and present four independent strong-field tests of general relativity. These tests use the theory-independent mass ratio of the two stars. By measuring relativistic corrections to the Keplerian description of the orbital motion, we find that the "post-Keplerian" parameter s agrees with the value predicted by general relativity within an uncertainty of 0.05%, the most precise test yet obtained. We also show that the transverse velocity of the system's center of mass is extremely small. Combined with the system's location near the Sun, this result suggests that future tests of gravitational theories with the double pulsar will supersede the best current solar system tests. It also implies that the second-born pulsar may not have formed through the core collapse of a helium star, as is usually assumed.

  2. Tests of general relativity from timing the double pulsar.

    PubMed

    Kramer, M; Stairs, I H; Manchester, R N; McLaughlin, M A; Lyne, A G; Ferdman, R D; Burgay, M; Lorimer, D R; Possenti, A; D'Amico, N; Sarkissian, J M; Hobbs, G B; Reynolds, J E; Freire, P C C; Camilo, F

    2006-10-01

    The double pulsar system PSR J0737-3039A/B is unique in that both neutron stars are detectable as radio pulsars. They are also known to have much higher mean orbital velocities and accelerations than those of other binary pulsars. The system is therefore a good candidate for testing Einstein's theory of general relativity and alternative theories of gravity in the strong-field regime. We report on precision timing observations taken over the 2.5 years since its discovery and present four independent strong-field tests of general relativity. These tests use the theory-independent mass ratio of the two stars. By measuring relativistic corrections to the Keplerian description of the orbital motion, we find that the "post-Keplerian" parameter s agrees with the value predicted by general relativity within an uncertainty of 0.05%, the most precise test yet obtained. We also show that the transverse velocity of the system's center of mass is extremely small. Combined with the system's location near the Sun, this result suggests that future tests of gravitational theories with the double pulsar will supersede the best current solar system tests. It also implies that the second-born pulsar may not have formed through the core collapse of a helium star, as is usually assumed. PMID:16973838

  3. Gravitation experiments at Stanford. [using general relativity theory

    NASA Technical Reports Server (NTRS)

    Lipa, J. A.

    1980-01-01

    The experimental situation in post-Newtonian gravitation is briefly reviewed in order to reexamine the extent to which experiment supports or refutes general relativity. A description is given of the equivalence principle project, the gyroscope experiment, and the search for gravity waves. It is noted that even though some doubt has been cast on the value of the perihelion advance and the gravitational redshift as precise tests of general relativity in the past few years, many competing theories have been ruled out; in particular, the results from the Viking mission significantly reduce the credibility of the Brans-Dicke theory (Brans and Dicke, 1961). The dimensionless constant omega in this theory is now forced to exceed 50, while the value originally proposed was 6 (omega being infinity in general relativity). It is noted that the gyro experiment described is capable of putting much tighter limits on this parameter, and together with the other experiments in progress will help place gravitational theory on a firmer experimental footing.

  4. Language Generativity, Response Generalization, and Derived Relational Responding

    PubMed Central

    Stewart, Ian; McElwee, John; Ming, Siri

    2013-01-01

    Language generativity can be described as the ability to produce sentences never before said, and to understand sentences never before heard. One process often cited as underlying language generativity is response generalization. However, though the latter seems to promise a technical understanding of the former at a process level, an investigation of definitions and approaches to the term “response generalization” that appear in the literature suggests that it does not do so. We argue that a more promising candidate for the role of key process underlying language generativity is derived relational responding. We introduce the latter concept and describe empirical research showing its connection with language. We subsequently present a relational frame theory (RFT) conceptualization of derived relations as contextually controlled generalized relational responding. We then review a series of recent studies on derived manding in developmentally delayed children and adults that arguably demonstrate the applied utility of a derived relations-based approach with respect to the phenomenon of generative language. PMID:23814374

  5. Anaphylactic bronchospasm during general anesthesia is not related to asthma.

    PubMed

    Gouel-Chéron, A; Neukirch, C; Aubier, B; Montravers, P; Nicaise, P; Chollet-Martin, S; Mertes, P-M; Aubier, M; Longrois, D

    2015-04-01

    In the general population, a history of asthma (HA) is associated with a higher risk of mortality of anaphylactic shock (AS), but it is unknown whether this association remains valid for intra-operative AS. The goal of this retrospective study was to investigate whether a HA was associated with a higher risk of bronchospasm during intra-operative AS. We analyzed 106 patients (January 2009-December 2012) with intra-operative AS: 57% of them had a confirmed IgE-mediated reaction and 27% had a HA. On logistic regression, the only factor statistically associated with bronchospasm was a neuromuscular blocking drug, with both IgE- or non-IgE-mediated reactions. These results suggest that the mechanisms of bronchospasm in AS may be different from those of asthma and that, in the presence of bronchospasm during anesthesia, AS should be considered to be the most likely cause. PMID:25556961

  6. Estimates of benefits and harms of prophylactic use of aspirin in the general population

    PubMed Central

    Cuzick, J.; Thorat, M. A.; Bosetti, C.; Brown, P. H.; Burn, J.; Cook, N. R.; Ford, L. G.; Jacobs, E. J.; Jankowski, J. A.; La Vecchia, C.; Law, M.; Meyskens, F.; Rothwell, P. M.; Senn, H. J.; Umar, A.

    2015-01-01

    Background Accumulating evidence supports an effect of aspirin in reducing overall cancer incidence and mortality in the general population. We reviewed current data and assessed the benefits and harms of prophylactic use of aspirin in the general population. Methods The effect of aspirin for site-specific cancer incidence and mortality, cardiovascular events was collated from the most recent systematic reviews. Studies identified through systematic Medline search provided data regarding harmful effects of aspirin and baseline rates of harms like gastrointestinal bleeding and peptic ulcer. Results The effects of aspirin on cancer are not apparent until at least 3 years after the start of use, and some benefits are sustained for several years after cessation in long-term users. No differences between low and standard doses of aspirin are observed, but there were no direct comparisons. Higher doses do not appear to confer additional benefit but increase toxicities. Excess bleeding is the most important harm associated with aspirin use, and its risk and fatality rate increases with age. For average-risk individuals aged 50–65 years taking aspirin for 10 years, there would be a relative reduction of between 7% (women) and 9% (men) in the number of cancer, myocardial infarction or stroke events over a 15-year period and an overall 4% relative reduction in all deaths over a 20-year period. Conclusions Prophylactic aspirin use for a minimum of 5 years at doses between 75 and 325 mg/day appears to have favourable benefit–harm profile; longer use is likely to have greater benefits. Further research is needed to determine the optimum dose and duration of use, to identify individuals at increased risk of bleeding, and to test effectiveness of Helicobacter pylori screening–eradication before starting aspirin prophylaxis. PMID:25096604

  7. Health Benefits for Vocational Rehabilitation Consumers: Comparison of Access Rates with Workers in the General Population

    ERIC Educational Resources Information Center

    Lustig, Daniel C.; Strauser, David R.

    2010-01-01

    Access to health insurance is one of the critical aspects of securing employment for people with disabilities. This study investigated whether vocational rehabilitation consumers secured employment with an employer who offered health insurance at similar rates to workers in the general population. In general, the results show that vocational…

  8. The Factor Structure of ADHD in a General Population of Primary School Children

    ERIC Educational Resources Information Center

    Ullebo, Anne Karin; Breivik, Kyrre; Gillberg, Christopher; Lundervold, Astri J.; Posserud, Maj-Britt

    2012-01-01

    Objective: To examine whether a bifactor model with a general ADHD factor and domain specific factors of inattention, hyperactivity and impulsivity was supported in a large general population sample of children. We also explored the utility of forming subscales based on the domain-specific factors. Methods: Child mental health questionnaires were…

  9. PDRK: A General Kinetic Dispersion Relation Solver for Magnetized Plasma

    NASA Astrophysics Data System (ADS)

    Xie, Huasheng; Xiao, Yong

    2016-02-01

    A general, fast, and effective approach is developed for numerical calculation of kinetic plasma linear dispersion relations. The plasma dispersion function is approximated by J-pole expansion. Subsequently, the dispersion relation is transformed to a standard matrix eigenvalue problem of an equivalent linear system. Numerical solutions for the least damped or fastest growing modes using an 8-pole expansion are generally accurate; more strongly damped modes are less accurate, but are less likely to be of physical interest. In contrast to conventional approaches, such as Newton's iterative method, this approach can give either all the solutions in the system or a few solutions around the initial guess. It is also free from convergence problems. The approach is demonstrated for electrostatic dispersion equations with one-dimensional and two-dimensional wavevectors, and for electromagnetic kinetic magnetized plasma dispersion relation for bi-Maxwellian distribution with relative parallel velocity flows between species. supported by the National Magnetic Confinement Fusion Science Program of China (Nos. 2015GB110003, 2011GB105001, 2013GB111000), National Natural Science Foundation of China (No. 91130031), the Recruitment Program of Global Youth Experts

  10. Genetic Determinants of Age-Related Macular Degeneration in Diverse Populations From the PAGE Study

    PubMed Central

    Restrepo, Nicole A.; Spencer, Kylee L.; Goodloe, Robert; Garrett, Tiana A.; Heiss, Gerardo; Bůžková, Petra; Jorgensen, Neal; Jensen, Richard A.; Matise, Tara C.; Hindorff, Lucia A.; Klein, Barbara E. K.; Klein, Ronald; Wong, Tien Y.; Cheng, Ching-Yu; Cornes, Belinda K.; Tai, E.-Shyong; Ritchie, Marylyn D.; Haines, Jonathan L.; Crawford, Dana C.

    2014-01-01

    Purpose. Substantial progress has been made in identifying susceptibility variants for AMD in European populations; however, few studies have been conducted to understand the role these variants play in AMD risk in diverse populations. The present study aims to examine AMD risk across diverse populations in known and suspected AMD complement factor and lipid-related loci. Methods. Targeted genotyping was performed across study sites for AMD and lipid trait-associated single nucleotide polymorphism (SNPs). Genetic association tests were performed at individual sites and then meta-analyzed using logistic regression assuming an additive genetic model stratified by self-described race/ethnicity. Participants included cases with early or late AMD and controls with no signs of AMD as determined by fundus photography. Populations included in this study were European Americans, African Americans, Mexican Americans, and Singaporeans from the Population Architecture using Genomics and Epidemiology (PAGE) study. Results. Index variants of AMD, rs1061170 (CFH) and rs10490924 (ARMS2), were associated with AMD at P = 3.05 × 10−8 and P = 6.36 × 10−6, respectively, in European Americans. In general, none of the major AMD index variants generalized to our non-European populations with the exception of rs10490924 in Mexican Americans at an uncorrected P value < 0.05. Four lipid-associated SNPS (LPL rs328, TRIB1 rs6987702, CETP rs1800775, and KCTD10/MVK rs2338104) were associated with AMD in African Americans and Mexican Americans (P < 0.05), but these associations did not survive strict corrections for multiple testing. Conclusions. While most associations did not generalize in the non-European populations, variants within lipid-related genes were found to be associated with AMD. This study highlights the need for larger well-powered studies in non-European populations. PMID:25205864

  11. Mimicking static anisotropic fluid spheres in general relativity

    NASA Astrophysics Data System (ADS)

    Boonserm, Petarpa; Ngampitipan, Tritos; Visser, Matt

    2016-11-01

    We argue that an arbitrary general relativistic static anisotropic fluid sphere, (static and spherically symmetric but with transverse pressure not equal to radial pressure), can nevertheless be successfully mimicked by suitable linear combinations of theoretically attractive and quite simple classical matter: a classical (charged) isotropic perfect fluid, a classical electromagnetic field and a classical (minimally coupled) scalar field. While the most general decomposition is not unique, a preferred minimal decomposition can be constructed that is unique. We show how the classical energy conditions for the anisotropic fluid sphere can be related to energy conditions for the isotropic perfect fluid, electromagnetic field, and scalar field components of the model. Furthermore, we show how this decomposition relates to the distribution of both electric charge density and scalar charge density throughout the model. The generalized TOV equation implies that the perfect fluid component in this model is automatically in internal equilibrium, with pressure forces, electric forces, and scalar forces balancing the gravitational pseudo-force. Consequently, we can build theoretically attractive matter models that can be used to mimic almost any static spherically symmetric spacetime.

  12. Testing general relativity using golden black-hole binaries

    NASA Astrophysics Data System (ADS)

    Ghosh, Abhirup; Ghosh, Archisman; Johnson-McDaniel, Nathan K.; Mishra, Chandra Kant; Ajith, Parameswaran; Del Pozzo, Walter; Nichols, David A.; Chen, Yanbei; Nielsen, Alex B.; Berry, Christopher P. L.; London, Lionel

    2016-07-01

    The coalescences of stellar-mass black-hole binaries through their inspiral, merger, and ringdown are among the most promising sources for ground-based gravitational-wave (GW) detectors. If a GW signal is observed with sufficient signal-to-noise ratio, the masses and spins of the black holes can be estimated from just the inspiral part of the signal. Using these estimates of the initial parameters of the binary, the mass and spin of the final black hole can be uniquely predicted making use of general-relativistic numerical simulations. In addition, the mass and spin of the final black hole can be independently estimated from the merger-ringdown part of the signal. If the binary black-hole dynamics is correctly described by general relativity (GR), these independent estimates have to be consistent with each other. We present a Bayesian implementation of such a test of general relativity, which allows us to combine the constraints from multiple observations. Using kludge modified GR waveforms, we demonstrate that this test can detect sufficiently large deviations from GR and outline the expected constraints from upcoming GW observations using the second-generation of ground-based GW detectors.

  13. Physical constraints on causality-violating spacetimes in general relativity

    NASA Astrophysics Data System (ADS)

    Janca, Andrew Joseph

    The theoretical possibility of global causality violation has long been a problem within general relativity, for there exists a large number of model spacetimes known to admit closed time-like curves, trajectories allowing a timelike observer to return to some point in her own past. However, nearly all such known models have some unphysical feature. These physicality issues rendered causality-violation to the status of an interesting but safely theoretical problem until twenty years ago, when the appearance of a new type of causality-violating model spacetime and the subsequent proliferation of new models admitting closed timelike curves forced the attention of the community to the issue, and made causality violation and its possible physical consequences an active area of research within general relativity. This paper focuses on some of the older causality-violating spacetimes which model matter sources with cylindrical symmetry. By describing how cylindrically-symmetric solutions can be embedded within a spatially bounded and physically realistic body which outwardly has the symmetry of a torus or ring, it is shown that the chief problem of physical plausibility which these older solutions possess can be resolved. The intention is to make these models active candidates for consideration in future experiments to test general relativity's prediction that causality violation is a phenomenon that could be observed in the real world. Attending chapters describe physical systems other than rotating objects that can alter a local observer's experience of time to a substantial extent, including an electrically-charged massive shell slowing time in its interior (though not affecting causality) and a class of trajectories in the Reissner-Nordstrom background that could in principle allow a timelike observer to reverse her personal arrow of time relative to other observers in the spacetime as a whole. The paper concludes with a discussion of one of the plausibility problems

  14. Profound effects of population density on fitness-related traits in an invasive freshwater snail.

    PubMed

    Zachar, Nicholas; Neiman, Maurine

    2013-01-01

    Population density can profoundly influence fitness-related traits and population dynamics, and density dependence plays a key role in many prominent ecological and evolutionary hypotheses. Here, we evaluated how individual-level changes in population density affect growth rate and embryo production early in reproductive maturity in two different asexual lineages of Potamopyrgus antipodarum, a New Zealand freshwater snail that is an important model system for ecotoxicology and the evolution of sexual reproduction as well as a potentially destructive worldwide invader. We showed that population density had a major influence on individual growth rate and early-maturity embryo production, effects that were often apparent even when comparing treatments that differed in population density by only one individual. While individual growth rate generally decreased as population density increased, we detected a hump-shaped relationship between embryo production and density, with females from intermediate-density treatments producing the most embryos and females from low- and high-density treatments producing the fewest embryos. The two lineages responded similarly to the treatments, indicating that these effects of population density might apply more broadly across P. antipodarum. These results indicate that there are profound and complex relationships between population density, growth rate, and early-maturity embryo production in at least two lineages of this important model system, with potential implications for the study of invasive populations, research on the maintenance of sex, and approaches used in ecotoxicology.

  15. Structures of general relativity in dilaton-Maxwell electrodynamics

    NASA Astrophysics Data System (ADS)

    Kechkin, O. V.; Mosharev, P. A.

    2016-08-01

    It is shown that electro (magneto) static sector of Maxwell’s electrodynamics coupled to the dilaton field in a string theory form possesses the symmetry group of the stationary General Relativity in vacuum. Performing the Ernst formalism, we develope a technique for generation of exact solutions in this modified electrodynamics on the base of the normalized Ehlers symmetry transformation. In the electrostatic case, we construct and study a general class of spherically symmetric solutions that describes a pointlike source of the Coulomb type. It is demonstrated that this source is characterized by finite and singularity-free interaction at short distances. Also it is established that the total electrostatic energy of this source is finite and inversely proportional to the dilaton-Maxwell coupling constant.

  16. Ab Initio Pulsar Magnetosphere: The Role of General Relativity

    NASA Astrophysics Data System (ADS)

    Philippov, Alexander A.; Cerutti, Benoît; Tchekhovskoy, Alexander; Spitkovsky, Anatoly

    2015-12-01

    It has recently been demonstrated that self-consistent particle-in-cell simulations of low-obliquity pulsar magnetospheres in flat spacetime show weak particle acceleration and no pair production near the poles. We investigate the validity of this conclusion in a more realistic spacetime geometry via general-relativistic particle-in-cell simulations of the aligned pulsar magnetosphere with pair formation. We find that the addition of the frame-dragging effect makes the local current density along the magnetic field larger than the Goldreich–Julian value, which leads to unscreened parallel electric fields and the ignition of a pair cascade. When pair production is active, we observe field oscillations in the open field bundle, which could be related to pulsar radio emission. We conclude that general-relativistic effects are essential for the existence of the pulsar mechanism in low-obliquity rotators.

  17. AB INITIO PULSAR MAGNETOSPHERE: THE ROLE OF GENERAL RELATIVITY

    SciTech Connect

    Philippov, Alexander A.; Cerutti, Benoit; Spitkovsky, Anatoly; Tchekhovskoy, Alexander

    2015-12-20

    It has recently been demonstrated that self-consistent particle-in-cell simulations of low-obliquity pulsar magnetospheres in flat spacetime show weak particle acceleration and no pair production near the poles. We investigate the validity of this conclusion in a more realistic spacetime geometry via general-relativistic particle-in-cell simulations of the aligned pulsar magnetosphere with pair formation. We find that the addition of the frame-dragging effect makes the local current density along the magnetic field larger than the Goldreich–Julian value, which leads to unscreened parallel electric fields and the ignition of a pair cascade. When pair production is active, we observe field oscillations in the open field bundle, which could be related to pulsar radio emission. We conclude that general-relativistic effects are essential for the existence of the pulsar mechanism in low-obliquity rotators.

  18. Experimental tests of pseudo-complex General Relativity

    NASA Astrophysics Data System (ADS)

    Schönenbach, Thomas; Caspar, Gunther; Hess, Peter O.; Boller, Thomas; Müller, Andreas; Schäfer, Mirko; Greiner, Walter

    2013-04-01

    Based on previous publications exploring pseudo-complex General Relativity (pc-GR) we present a selection of observable consequences of pc-GR and possible ways to experimentally access them. Whenever possible we compare the results to Einstein's GR and differences are worked out in detail. We propose experimental tests to check the predictions of pc-GR for the orbital frequency of test particles, the gravitational redshift effect and the last stable orbit. We will show that the orbital frequency of test particles at a given radius in pc-GR is in general lower compared to standard GR. Also the effect of frame dragging is modified (weakened) in pc-GR. Concerning the gravitational redshift of a radiation emitting object we find that it is also lower in pc-GR than in standard GR. Eventually, the classical concept of a last stable orbit has to be modified in pc-GR.

  19. Hyperbolicity of physical theories with application to general relativity

    NASA Astrophysics Data System (ADS)

    Hilditch, David; Richter, Ronny

    2016-08-01

    We consider gauge theories from the free evolution point of view, in which initial data satisfying constraints of a theory are given, and because the constraints satisfy a closed evolution system, they remain so. We study a model constrained Hamiltonian theory and identify a particular structure in the equations of motion which we call the standard gauge freedom. The pure gauge subsystem of this model theory is identified, and the manner in which the gauge variables couple to the field equations is presented. We demonstrate that the set of gauge choices that can be coupled to the field equations to obtain a strongly hyperbolic formulation is exactly the set of strongly hyperbolic pure gauges. Consequently we analyze a parametrized family of formulations of general relativity. The generalization of the harmonic gauge formulation to a five parameter family of gauge conditions is obtained.

  20. Guidelines for composite materials research related to general aviation aircraft

    NASA Technical Reports Server (NTRS)

    Dow, N. F.; Humphreys, E. A.; Rosen, B. W.

    1983-01-01

    Guidelines for research on composite materials directed toward the improvement of all aspects of their applicability for general aviation aircraft were developed from extensive studies of their performance, manufacturability, and cost effectiveness. Specific areas for research and for manufacturing development were identified and evaluated. Inputs developed from visits to manufacturers were used in part to guide these evaluations, particularly in the area of cost effectiveness. Throughout the emphasis was to direct the research toward the requirements of general aviation aircraft, for which relatively low load intensities are encountered, economy of production is a prime requirement, and yet performance still commands a premium. A number of implications regarding further directions for developments in composites to meet these requirements also emerged from the studies. Chief among these is the need for an integrated (computer program) aerodynamic/structures approach to aircraft design.

  1. Prevalence of impairments, disabilities, handicaps and quality of life in the general population: a review of recent literature.

    PubMed Central

    Barbotte, E.; Guillemin, F.; Chau, N.

    2001-01-01

    OBJECTIVE: To determine the prevalence rates of morbidity in the general population through bibliographic research. METHODS: Articles relating to impairment, disability, handicap, quality of life and their prevalence in the general population, published between January 1990 and March 1998, were selected on the MEDLINE database. FINDINGS: The 20 articles retained out of 433 used 41 different indicators. Indicators of impairment, disability, handicap and low quality of life showed prevalence rates of 0.1-92%, 3.6-66%, 0.6-56% and 1.8-26% respectively, depending on age and the accuracy of indicators. The heterogeneity of the conceptual framework and insufficient recognition of the importance of indicator accuracy, the age factor and the socioeconomic characteristics of the studied populations impede reliable international comparison. CONCLUSION: Further standardization of indicators is therefore required. The revision of the International Classification of Impairments, Disabilities and Handicaps may make it possible to resolve some of the difficulties encountered. PMID:11731812

  2. A walk-in screening of dementia in the general population in Taiwan.

    PubMed

    Chen, Chun-Hung; Wang, Ling-Chun; Ma, Tzu-Chiao; Yang, Yuan-Han

    2014-01-01

    Alzheimer's disease (AD) has increased in its prevalence due to the increasing aged population. Currently there is no updated data on the prevalence of dementia including its very mild stage in Taiwan. Under the extensive coverage of Mentality Protection Center (MPC), Fo Guang Shan, Taiwan, the volunteers of MPC have conducted the medicine-related services and the screening of dementia by AD8 (ascertainment of dementia 8) that can screen the dementia even at its very mild stage in general population in all Taiwan. From 2011 to 2013, in total, 2,171 participants, 368 in the northern, 549 in the central, 877 in the southern, and 377 in the eastern part, were recruited with the mean age being 66.9 ± 10.2 years old. The ratio of suspected dementia patients, AD8 score greater than or equal to 2, was 13.6% of all recruited participants with their mean AD8 score being 2.9 ± 1.3, mean age being 69.4 ± 10.8 years old, and female predominance being 73.0%. Although this is a screening study, it has extensive coverage of all Taiwan and the use of AD8 is capable of screening very mild dementia. A further study with a randomized sampling to examine the prevalence and incidence of dementia including its very mild stage is encouraged. PMID:24883363

  3. Dairy intake, blood pressure, and incident hypertension in a general Dutch population.

    PubMed

    Engberink, Mariëlle F; Geleijnse, Johanna M; de Jong, Nynke; Smit, Henriette A; Kok, Frans J; Verschuren, W M Monique

    2009-03-01

    Diet and lifestyle are important for maintaining a healthy blood pressure (BP). The role of dairy in the prevention of hypertension, however, is not yet clear. We studied the relation of dairy intake with BP in 21,553 Dutch participants aged 20-65 y who did not use antihypertensive medication. In addition, the risk of hypertension was examined in 3454 of these participants with a 5-y follow-up. Dairy consumption was assessed at baseline (1993-1997) using a semiquantitative FFQ that included 178 foods and beverages. Baseline BP and odds ratios (OR) (95% CI) for incident hypertension were calculated in categories of energy-adjusted dairy intake with adjustment for age, sex, socioeconomic status, BMI, smoking, alcohol use, and dietary intakes. Participants had a median intake of 344 g/d (approximately 2.3 servings) for total dairy and 174 g/d (approximately 1.2 servings) for low-fat dairy. Mean BP was 120/76 mm Hg. Intake of total dairy, specific dairy groups (i.e. low-fat, high-fat, fermented) and dairy products (i.e. cheese, yogurt) were not consistently related to BP. Of 3454 participants who were followed, 713 developed hypertension. The risk of hypertension tended to be inversely related to low-fat dairy intake, with multivariate OR (95% CI) of 1.00, 0.78 (0.61, 1.00), 0.81 (0.63, 1.03), and 0.82 (0.64, 1.06; P-trend: 0.24) in consecutive quartiles. We conclude that variations in BP in a general middle-aged Dutch population cannot be explained by overall dairy intake. A beneficial effect of low-fat dairy on risk of hypertension, however, cannot be excluded, which warrants further investigation in prospective population-based studies.

  4. Derivation of Einstein-Cartan theory from general relativity

    NASA Astrophysics Data System (ADS)

    Petti, Richard

    2016-03-01

    This article presents a derivation of Einstein-Cartan theory from general relativity with no additional assumptions or parameters. The derivation begins with distributions of Kerr masses that converge to a continuum with constant densities of mass, momentum, and angular momentum. The limit includes torsion and the spin-torsion relationship of Einstein-Cartan theory. The construction of curvature and torsion is equivalent to definition of curvature with Cartan forms on fiber bundles. Advantages of Einstein-Cartan theory include accommodating exchange of classical intrinsic and orbital angular momentum and generation of inflation-like expansion in high density cosmological models.

  5. Vector order parameter in general relativity: Covariant equations

    SciTech Connect

    Meierovich, Boris E.

    2010-07-15

    Phase transitions with spontaneous symmetry breaking and vector order parameter are considered in multidimensional theory of general relativity. Covariant equations, describing the gravitational properties of topological defects, are derived. The topological defects are classified in accordance with the symmetry of the covariant derivative of the vector order parameter. The abilities of the derived equations are demonstrated in application to the braneworld concept. New solutions of the Einstein equations with a transverse vector order parameter are presented. In the vicinity of phase transition, the solutions are found analytically.

  6. Testing general relativity in space-borne and astronomical laboratories

    NASA Technical Reports Server (NTRS)

    Will, Clifford M.

    1989-01-01

    The current status of space-based experiments and astronomical observations designed to test the theory of general relativity is surveyed. Consideration is given to tests of post-Newtonian gravity, searches for feeble short-range forces and gravitomagnetism, improved measurements of parameterized post-Newtonian parameter values, explorations of post-Newtonian physics, tests of the Einstein equivalence principle, observational tests of post-Newtonian orbital effects, and efforts to detect quadrupole and dipole radiation damping. Recent numerical results are presented in tables.

  7. Tests of general relativity using Starprobe radio metric tracking data

    NASA Technical Reports Server (NTRS)

    Mease, K. D.; Anderson, J. D.; Wood, L. J.; White, L. K.

    1982-01-01

    The potential of a proposed spacecraft mission, called Starprobe, for testing general relativity and providing information on the interior structure and dynamics of the sun is investigated. Parametric, gravitational perturbation terms are derived which represent relativistic effects and effects due to spatial and temporal variations in the solar potential at a given radial distance. A covariance analysis based on Kalman filtering theory predicts the accuracies with which the free parameters in the perturbation terms can be estimated with radio metric tracking data through the process of trajectory reconstruction. It is concluded that Starprobe can contribute significant information on both the nature of gravitation and the structure and dynamics of the solar interior.

  8. General relativity as a two-dimensional CFT

    NASA Astrophysics Data System (ADS)

    Adamo, Tim

    2015-11-01

    The tree-level scattering amplitudes of general relativity (GR) encode the full nonlinearity of the Einstein field equations. Yet remarkably compact expressions for these amplitudes have been found which seem unrelated to a perturbative expansion of the Einstein-Hilbert action. This suggests an entirely different description of GR which makes this on-shell simplicity manifest. Taking our cue from the tree-level amplitudes, we discuss how such a description can be found. The result is a formulation of GR in terms of a solvable two-dimensional conformal field theory (CFT), with the Einstein equations emerging as quantum consistency conditions.

  9. A superconducting gyroscope to test Einstein's general theory of relativity

    NASA Technical Reports Server (NTRS)

    Everitt, C. W. F.

    1978-01-01

    Schiff (1960) proposed a new test of general relativity based on measuring the precessions of the spin axes of gyroscopes in earth orbit. Since 1963 a Stanford research team has been developing an experiment to measure the two effects calculated by Schiff. The gyroscope consists of a uniform sphere of fused quartz 38 mm in diameter, coated with superconductor, electrically suspended and spinning at about 170 Hz in vacuum. The paper describes the proposed flight apparatus and the current state of development of the gyroscope, including techniques for manufacturing and measuring the gyro rotor and housing, generating ultralow magnetic fields, and mechanizing the readout.

  10. Minimum length from quantum mechanics and classical general relativity.

    PubMed

    Calmet, Xavier; Graesser, Michael; Hsu, Stephen D H

    2004-11-19

    We derive fundamental limits on measurements of position, arising from quantum mechanics and classical general relativity. First, we show that any primitive probe or target used in an experiment must be larger than the Planck length lP. This suggests a Planck-size minimum ball of uncertainty in any measurement. Next, we study interferometers (such as LIGO) whose precision is much finer than the size of any individual components and hence are not obviously limited by the minimum ball. Nevertheless, we deduce a fundamental limit on their accuracy of order lP. Our results imply a device independent limit on possible position measurements.

  11. Expanding General Relativity's Space by S-Denying

    NASA Astrophysics Data System (ADS)

    Rabounski, Dmitri; Smarandache, Florentins; Borissova, Larissa

    2016-05-01

    Applying the S-denying procedure to signature conditions in a four-dimensional pseudo-Riemannian space - i.e. changing one (or even all) of the conditions to be partially true and partially false. Obtaining five kinds of expanded space-time for General Relativity. Kind I permits the space-time to be in collapse. Kind II permits the space-time to change its own signature. Kind III has peculiarities, linked to the third signature condition. Kind IV permits regions where the metric fully degenerates: there may be non-quantum teleportation, and a home for virtual photons. Kind V is common for kinds I, II, III, and IV.

  12. Rotating black holes in the teleparallel equivalent of general relativity

    NASA Astrophysics Data System (ADS)

    Nashed, Gamal G. L.

    2016-05-01

    We derive set of solutions with flat transverse sections in the framework of a teleparallel equivalent of general relativity which describes rotating black holes. The singularities supported from the invariants of torsion and curvature are explained. We investigate that there appear more singularities in the torsion scalars than in the curvature ones. The conserved quantities are discussed using Einstein-Cartan geometry. The physics of the constants of integration is explained through the calculations of conserved quantities. These calculations show that there is a unique solution that may describe true physical black hole.

  13. Comparison of stage at diagnosis of cancer in patients on dialysis versus the general population

    PubMed Central

    Taneja, Shilpa; Mandayam, Sreedhar; Kayani, Zainab Z.; Kuo, Yong-Fang; Shahinian, Vahakn B.

    2008-01-01

    Background The frequent medical encounters in end-stage renal disease (ESRD) patients on dialysis may allow early detection of malignancies despite generally low rates of cancer screening in this population. It is therefore unclear whether dialysis patients are disadvantaged in terms of cancer diagnosis. To address this issue, we compared stage at diagnosis of cancer in a population-based sample of ESRD patients versus the general population. Methods The Surveillance, Epidemiology and End-Results (SEER)-Medicare database was used to identify ESRD patients with incident cancers from 1992 through 1999. Modified Poisson regression models were used to predict non-localized stage of cancer at diagnosis in ESRD patients versus the general population adjusting for demographics, cancer site, region, year of diagnosis and comorbidity. Two general population comparisons were used: standardized SEER public use data and Medicare non-ESRD controls matched 3:1 to ESRD patients. Results A total of 1629 ESRD patients with incident cancer were identified. Overall, the likelihood of non-localized stage at diagnosis was not significantly different for ESRD patients versus the standardized SEER general population (RR 0.90; 95%CI: 0.81-1.01) or matched Medicare controls (RR 0.97; 95%CI: 0.89-1.07). When analyzed by cancer site, colorectal cancers were significantly more likely to be diagnosed earlier in the ESRD group, whereas prostate cancers were significantly more likely to be diagnosed at a later stage. Conclusion In conclusion, this study demonstrates that, with the notable exception of prostate cancer, ESRD patients are not more likely to present with later stage malignancies compared to the general population. PMID:17702737

  14. Sexually coercive behavior in male youth: population survey of general and specific risk factors.

    PubMed

    Kjellgren, Cecilia; Priebe, Gisela; Svedin, Carl Göran; Långström, Niklas

    2010-10-01

    Little is known about risk/protective factors for sexually coercive behavior in general population youth. We used a Swedish school-based population survey of sexual attitudes and experiences (response rate 77%) and investigated literature-based variables across sexually coercive (SEX), non-sexual conduct problem (CP), and normal control (NC) participants to identify general and specific risk/protective factors for sexual coercion. Among 1,933 male youth, 101 (5.2%) reported sexual coercion (ever talked or forced somebody into genital, oral, or anal sex) (SEX), 132 (6.8%) were classified as CP, and the remaining 1,700 (87.9%) as NC. Of 29 tested variables, 25 were more common in both SEX and CP compared to NC youth, including minority ethnicity, separated parents, vocational study program, risk-taking, aggressiveness, depressive symptoms, substance abuse, sexual victimization, extensive sexual experiences, and sexual preoccupation. When compared to CP youth only, SEX youth more often followed academic study programs, used less drugs and were less risk-taking. Further, SEX more frequently than CP youth reported gender stereotypic and pro-rape attitudes, sexual preoccupation, prostitution, and friends using violent porn. Finally, in a multivariate logistic regression, academic study program, pro-rape attitudes, sexual preoccupation, and less risk-taking independently remained more strongly associated with SEX compared to CP offending. In conclusion, several sociodemographic, family, and individual risk/protective factors were common to non-sexual and sexually coercive antisocial behavior in late adolescence. However, pro-rape cognitions, and sexual preoccupation, were sexuality-related, specific risk factors. The findings could inform preventive efforts and the assessment and treatment of sexually coercive male youth. PMID:19888644

  15. Brominated flame retardants - Exposure and risk assessment for the general population.

    PubMed

    Fromme, H; Becher, G; Hilger, B; Völkel, W

    2016-01-01

    Brominated flame retardants (BFRs) are a large group of different substances used in numerous products to prevent fire hazards. Some of them are persistent in the environment, accumulate in the food chain and are of toxicological concern, while for others current data are limited. Meanwhile, BFRs have been found in many environmental media, foods, and biota including humans. This review presents recent findings obtained from monitoring data in environmental media relevant for human exposure, as well as dietary exposure. In this context, concentrations in indoor and ambient air and in house dust are outlined. Furthermore, we summarize human biomonitoring data on BFR levels in blood and breast milk. Current estimates of the overall exposure of the general population using different relevant subsets are also addressed. All of these data are discussed in relation to currently available toxicological reference values used for risk assessment purposes. Obviously, the exposure of the general population varies considerably in different parts of the world and even within countries. Polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecane (HBCD) show the highest intake during infancy. While the highest intake for BDE 47 for all groups was observed in the US, the total BDE 209 and HBCD intake was highest in the UK. For HBCD and all PBDEs except BDE 209, diet accounts for a large proportion of the total intake during infancy in all countries. With regard to toddlers and adults, the contribution of diet to total intake is high in Germany and the UK, while in the US, the high concentrations of PBDE in dust resulted in a notably smaller proportion of the intake being attributed to diet.

  16. Association between Serum Uric Acid and Elevated Alanine Aminotransferase in the General Population

    PubMed Central

    Chen, Shuang; Guo, Xiaofan; Yu, Shasha; Sun, Guozhe; Yang, Hongmei; Li, Zhao; Sun, Yingxian

    2016-01-01

    Background: Both the serum uric acid (SUA) level and elevated alanine aminotransferase (ALT) are related to metabolic syndrome. However, the association between SUA and elevated ALT has not been elucidated in the general population. The objective of this study was to investigate the association between SUA and elevated ALT in the general population of China; Methods: A total of 11,572 adults (≥35 years of age) participated in this survey. Elevated ALT was defined as >40 U/L. SUA ≥ 7.0 mg/dL in males or ≥6.0 mg/dL in females was defined as hyperuricemia. SUA within the reference range was divided into quartiles, and its associations with elevated ALT were evaluated by logistic regressions; Results: A total of 7.4% participants had elevated ALT. The prevalence of hyperuricemia was 14.9% in males and 7.3% in females. There was a significantly positive dose-response association between SUA levels and the prevalence of elevated ALT. After adjusting for potential confounders, a positive relationship for elevated ALT was observed in subjects with hyperuricemia (odds ratio [OR]: 2.032, 95% confidence interval [CI]: 1.443–2.861 for men; OR: 2.045, 95% CI: 1.221–3.425 for women, both p < 0.05). Within the reference range, the association between SUA and elevated ALT persisted in the fourth quartile (OR: 1.467, 95% CI: 1.063–2.025 for men; OR: 1.721, 95% CI: 1.146–2.585 for women, both p < 0.05); Conclusions: Our results indicated that an increased SUA level, even within the reference range, was independently associated with elevated ALT in Chinese adults. PMID:27563918

  17. Mental-Physical Comorbidity in Korean Adults: Results from a Nationwide General Population Survey in Korea

    PubMed Central

    Kim, Ji-Hyun; Bae, Jae Nam; Cho, Seong-Jin; Lee, Jun-Young; Kim, Byung-Soo; Cho, Maeng Je

    2016-01-01

    Objective The aims of this study were to estimate the prevalence of mental-physical comorbidity and health-threatening risk factors in subjects with mental disorders, and the risks of mental disorders in those with physical diseases for the last 12 months in the general Korean population. Methods Korean Epidemiologic Catchment Area study replication (KECA-R) was conducted for 6,510 adults between August 2006 and April 2007. The Korean version of Composite International Diagnostic Interview 2.1 (K-CIDI) was used in the survey. Prevalence of mental and physical disorders, and risk factors for physical health were calculated, and their associations were evaluated with adjustment for age and sex. Results Subjects with any mental disorder showed significantly higher prevalence of chronic physical conditions (adjusted odds ratio, AOR=1.5 to 2.8, p<0.001) and medical risk factors including smoking, heavy drinking, overweight, and hypertension (AOR=1.5 to 4.0, p<0.001). Of those with chronic physical conditions, 21.6% had one or more comorbid mental disorder compared with 10.5% of the subjects without chronic physical disorders (AOR=2.6, p<0.001). Contrary to expectations, depressive disorders did not show significant association with hypertension and prevalence of obesity was not influenced by presence of mental disorders. Further studies should assess these findings. Conclusion This is the first identification of significant mental-physical comorbidity in the general Korean population. Clinicians and health care officials should keep in mind of its potential adverse effects on treatment outcome and aggravated disease-related socioeconomic burden. PMID:27757127

  18. Sexually coercive behavior in male youth: population survey of general and specific risk factors.

    PubMed

    Kjellgren, Cecilia; Priebe, Gisela; Svedin, Carl Göran; Långström, Niklas

    2010-10-01

    Little is known about risk/protective factors for sexually coercive behavior in general population youth. We used a Swedish school-based population survey of sexual attitudes and experiences (response rate 77%) and investigated literature-based variables across sexually coercive (SEX), non-sexual conduct problem (CP), and normal control (NC) participants to identify general and specific risk/protective factors for sexual coercion. Among 1,933 male youth, 101 (5.2%) reported sexual coercion (ever talked or forced somebody into genital, oral, or anal sex) (SEX), 132 (6.8%) were classified as CP, and the remaining 1,700 (87.9%) as NC. Of 29 tested variables, 25 were more common in both SEX and CP compared to NC youth, including minority ethnicity, separated parents, vocational study program, risk-taking, aggressiveness, depressive symptoms, substance abuse, sexual victimization, extensive sexual experiences, and sexual preoccupation. When compared to CP youth only, SEX youth more often followed academic study programs, used less drugs and were less risk-taking. Further, SEX more frequently than CP youth reported gender stereotypic and pro-rape attitudes, sexual preoccupation, prostitution, and friends using violent porn. Finally, in a multivariate logistic regression, academic study program, pro-rape attitudes, sexual preoccupation, and less risk-taking independently remained more strongly associated with SEX compared to CP offending. In conclusion, several sociodemographic, family, and individual risk/protective factors were common to non-sexual and sexually coercive antisocial behavior in late adolescence. However, pro-rape cognitions, and sexual preoccupation, were sexuality-related, specific risk factors. The findings could inform preventive efforts and the assessment and treatment of sexually coercive male youth.

  19. Diagnostic health risk assessment of electronic waste on the general population in developing countries' scenarios

    SciTech Connect

    Frazzoli, Chiara; Orisakwe, Orish Ebere; Dragone, Roberto; Mantovani, Alberto

    2010-11-15

    E-waste is the generic name for technological waste. Even though aspects related to e-waste environmental pollution and human exposure are known, scientific assessments are missing so far on the actual risks for health sustainability of the general population exposed to e-waste scenarios, such as illicit dumping, crude recycling and improper treatment and disposal. In fact, further to occupational and direct local exposure, e-waste scenarios may impact on the environment-to-food chain, thus eliciting a widespread and repeated exposure of the general population to mixtures of toxicants, mainly toxic chemical elements, polycyclic aromatic hydrocarbons and persistent organic pollutants. In the absence of any clear policy on e-waste flow management, the situation in the e-waste receiver countries may become quite scary; accordingly, here we address a diagnostic risk assessment of health issues potentially elicited by e-waste related mixtures of toxicants. Scientific evidence available so far (mainly from China) is discussed with special attention to the concept of health sustainability, i.e. the poor health burden heritage perpetuated through the mother-to-child dyad. Endocrine disruption and neurotoxicity are specifically considered as examples of main health burden issues relevant to perpetuation through life cycle and across generations; toxicological information are considered along with available data on environmental and food contamination and human internal exposure. The risk from exposure to e-waste related mixtures of toxicants of vulnerable subpopulation like breast-fed infants is given special attention. The diagnostic risk assessment demonstrates how e-waste exposure poses an actual public health emergency, as it may entrain significant health risks also for generations to come. Exposure scenarios as well as specific chemicals of major concern may vary in different contexts; for instance, only limited information is available on e-waste related exposures in

  20. BOOK REVIEW: A First Course in General Relativity (Second Edition) A First Course in General Relativity (Second Edition)

    NASA Astrophysics Data System (ADS)

    Poisson, Eric

    2010-05-01

    A few years ago, in my review of Sean Carroll's book in Classical and Quantum Gravity [1], I wrote that while the 1970s was the decade of Weinberg [2] and Misner, Thorne and Wheeler [3], and while the eighties was the decade of Schutz [4] and Wald [5], the 2000s was clearly the decade of Hartle [6] and Carroll [7]. In my opinion, these books continue to stand out in the surprisingly dense crowd of introductory textbooks on general relativity. At the dawn of this new decade I look forward to see what fresh pedagogical insights will be produced next, and who will be revealed as the winners of the 2010s. It is, of course, much too early to tell, but Schutz is back, and he will set the standard just as he did back in 1985. This is the long-awaited second edition of his `First Course', a short, accessible, and very successful introduction to general relativity. The changes from the first edition are modest: Schutz wisely refrained from bloating the text with new topics, and limited himself to updating his discussion of gravitational-wave sources and detectors, neutron-star and black-hole astrophysics, and suggestions for further reading. Most importantly, he completely rewrote the chapter on cosmology, a topic that has evolved enormously since the first edition. The book begins in chapter 1 with a beautiful review of special relativity that emphasizes spacetime geometry and stays away from an algebraic approach based on the Lorentz transformation, which appears only later in the chapter. This is followed up in chapters 2 and 3 with an introduction to vector and tensor analysis in flat spacetime. The point of view is modern (tensors are defined as linear mapping of vectors and one-forms into real numbers) but the presentation is very accessible and avoids an overload of mathematical fine print. In chapter 4 the book introduces the spacetime description of fluids; it is here that the energy-momentum tensor makes its first appearance. The move to curved spacetime is

  1. Testing general relativity with Landers on the Martian satellite Phobos

    NASA Technical Reports Server (NTRS)

    Anderson, J. D.; Borderies, N. J.; Campbell, J. K.; Dunne, J. A.; Ellis, J.

    1989-01-01

    A planned experiment to obtain range and Doppler data with the Phobos 2 Lander on the surface of the Martian satellite Phobos is described. With the successful insertion on January 29, 1989 of Phobos 2 into Mars orbit, it is anticipated that the Lander will be placed on the surface of Phobos in April 1989. Depending on the longevity of the Lander, range and Doppler data for a period of from one to several years are expected. Because these data are of value in performing solar-system tests of general relativity, the current accuracy of the relevant relativity tests using Deep Space Network data from the Mariner-9 orbiter of Mars in 1971 and from the Viking Landers in 1976-1982 is reviewed. The expected improvement from data anticipated during the Phobos 2 Lander Mission is also discussed; most important will be an improved sensitivity to any time variation in the gravitational 'constant' as measured in atomic units.

  2. Multiple stressor effects in relation to declining amphibian populations

    USGS Publications Warehouse

    2003-01-01

    This book represents the work of several authors who participated in the symposium entitled 'Multiple Stressor Effects in Relation to Declining Amphibian Populations' convened 16-17 April, 2002, in Pittsburgh, Pennsylvania. Declines of amphibian populations of varying severity have been observed for many years, and in the last 8 to 10 years considerable progress has been made in documenting the status and distribution of a range of amphibian species. Habitat alteration and destruction are likely linked to many amphibian declines, but a variety of other factors, both anthropogenic and natural, have been observed or proposed to have caused declines or extinctions of amphibian populations. Unfortunately, determining the environmental causes for the decline of many species has proven difficult. The goals of this symposium were three-fold. First, highlight ASTM's historic role in providing a forum for the standardization of amphibian toxicity test methods and the characterization of adverse effects potentially associated with chemical stressors. Second, demonstrate through case studies the current state of technical 'tools' available to biologists, ecologists, environmental scientists and natural resource professionals for assessing amphibian populations exposed to various environmental stressors. And third, characterize a process that brings a range of interdisciplinary technical and management tools to the tasks of causal analysis, especially as those relate to a multiple stressor risk assessment 'mind-set.' As part of the symposium, scientists and resource management professionals from diverse fields including ecotoxicology and chemistry, ecology and field biology, conservation biology, and natural resource management and policy contributed oral presentations and posters that addressed topics related to declining amphibian populations and the role that various stressors have in those losses. The papers contained in this publication reflect the commitment of ASTM

  3. Elliptical galaxies kinematics within general relativity with renormalization group effects

    SciTech Connect

    Rodrigues, Davi C.

    2012-09-01

    The renormalization group framework can be applied to Quantum Field Theory on curved space-time, but there is no proof whether the beta-function of the gravitational coupling indeed goes to zero in the far infrared or not. In a recent paper [1] we have shown that the amount of dark matter inside spiral galaxies may be negligible if a small running of the General Relativity coupling G is present (δG/G{sub 0}∼<10{sup −7} across a galaxy). Here we extend the proposed model to elliptical galaxies and present a detailed analysis on the modeling of NGC 4494 (an ordinary elliptical) and NGC 4374 (a giant elliptical). In order to compare our results to a well known alternative model to the standard dark matter picture, we also evaluate NGC 4374 with MOND. In this galaxy MOND leads to a significative discrepancy with the observed velocity dispersion curve and has a significative tendency towards tangential anisotropy. On the other hand, the approach based on the renormalization group and general relativity (RGGR) could be applied with good results to these elliptical galaxies and is compatible with lower mass-to-light ratios (of about the Kroupa IMF type)

  4. Matrix general relativity: a new look at old problems

    NASA Astrophysics Data System (ADS)

    Avramidi, Ivan G.

    2004-01-01

    We develop a novel approach to gravity that we call 'matrix general relativity' (MGR) or 'gravitational chromodynamics' (GCD or GQCD for the quantum version). Gravity is described in this approach not by one Riemannian metric (i.e. a symmetric two-tensor field) but by a multiplet of such fields, or by a matrix-valued symmetric two-tensor field that satisfies certain conditions. We define the matrix extensions of standard constructions of differential geometry including connections and curvatures, and finally, an invariant functional of the new field that reduces to the standard Einstein action functional in the commutative (diagonal) case. Our main idea is the analogy with Yang Mills theory (QCD and the standard model). We call the new degrees of freedom of gravity associated with the matrix structure 'gravitational colour' or simply 'gravicolour' and introduce a new gauge symmetry associated with this degree of freedom. As in the standard model there are two possibilities. First of all, it is possible that at high energies (say at the Planckian scale) this symmetry is exact (symmetric phase), but at low energies it is badly broken, so that one tensor field remains massless (and gives general relativity) and the other ones become massive with masses of Planckian scale. The second possibility is that the additional degrees of freedom of the gravitational field are confined to the Planckian scale. What one sees at large distances are singlets (invariants) of the new gauge symmetry.

  5. Psychological acculturation and juvenile delinquency: comparing Moroccan immigrant families from a general and pretrial detention population.

    PubMed

    Stevens, Gonneke W J M; Veen, Violaine C; Vollebergh, Wilma A M

    2014-04-01

    Although several theoretical notions have been proposed predicting a relationship between acculturation orientation and juvenile delinquency, the available empirical research is scarce and limited. To extend former research, in this study, we used latent class analyses to compare bidimensional psychological acculturation orientation of Moroccan immigrant boys in pretrial detention with those of Moroccan boys in the general population. We also examined their parents' acculturation orientation. We found that boys in pretrial detention were clearly overrepresented in the integrated psychological acculturation class and underrepresented in the separated psychological acculturation class when we compared them with the boys in the general population. Highly similar results were found for their parents. In contrast, boys in pretrial detention were as likely to be faced with an intergenerational acculturation gap as boys from the general population.

  6. Personality comparison of airline pilot incumbents, applicants, and the general population norms on the 16PF.

    PubMed

    Wakcher, Sandra; Cross, Kara; Blackman, Melinda C

    2003-06-01

    Personality comparisons using Cattell's 16PF were made between 137 pilot incumbents, 81 pilot applicants, and the general population norms. No significant differences were found between the scores on the personality factors for the Pilot Incumbents and the Pilot Applicants. Further, the incumbents and applicants who had previous military training versus those who did not had highly similar personalities. However, on nearly every personality factor a significant difference was found between the general population norms and the sample of Pilot Incumbents and Applicants. The Pilot Incumbent/Applicant group scored significantly more intelligent, emotionally stable, and mature in comparison to the general population norms. We believe that it is the high-risk nature of this occupation that leads applicants, wishing to pursue this field, to assess very carefully their own person-job fit and self-select themselves, thus ultimately producing this very distinct "pilot personality profile" described in 1995 by Bartram.

  7. Medically Unexplained and Explained Physical Symptoms in the General Population: Association with Prevalent and Incident Mental Disorders

    PubMed Central

    van Eck van der Sluijs, Jonna; ten Have, Margreet; Rijnders, Cees; van Marwijk, Harm; de Graaf, Ron; van der Feltz-Cornelis, Christina

    2015-01-01

    Background Clinical studies have shown that Medically Unexplained Symptoms (MUS) are related to common mental disorders. It is unknown how often common mental disorders occur in subjects who have explained physical symptoms (PHY), MUS or both, in the general population, what the incidence rates are, and whether there is a difference between PHY and MUS in this respect. Aim To study the prevalence and incidence rates of mood, anxiety and substance use disorders in groups with PHY, MUS and combined MUS and PHY compared to a no-symptoms reference group in the general population. Method Data were derived from the Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2), a nationally representative face-to-face survey of the general population aged 18-64 years. We selected subjects with explained physical symptoms only (n=1952), with MUS only (n=177), with both MUS and PHY (n=209), and a reference group with no physical symptoms (n=4168). The assessment of common mental disorders was through the Composite International Diagnostic Interview 3.0. Multivariate logistic regression analyses were used to examine the association between group membership and the prevalence and first-incidence rates of comorbid mental disorders, adjusted for socio-demographic characteristics. Results MUS were associated with the highest prevalence rates of mood and anxiety disorders, and combined MUS and PHY with the highest prevalence rates of substance disorder. Combined MUS and PHY were associated with a higher incidence rate of mood disorder only (OR 2.9 (95%CI:1.27,6.74)). Conclusion In the general population, PHY, MUS and the combination of both are related to mood and anxiety disorder, but odds are highest for combined MUS and PHY in relation to substance use disorder. Combined MUS and PHY are related to a greater incidence of mood disorder. These findings warrant further research into possibilities to improve recognition and early intervention in subjects with combined MUS and

  8. [Smoking habits in France among general practitioners and the general male population over a twenty-five year period (1966-1991)].

    PubMed

    Fréour, P; Tessier, J F

    1993-01-01

    Epidemiological surveys are presented regarding smoking habits among two populations: the general practitioners in France since 1966 to 1991 and the general population of adult men in the same period of time. We add some European and foreign surveys in the same groups of population. These data show a regular and rather slow reduction of percentage of smokers during the last 25 years. We can see, in general, the behaviour of the general practitioners are in advance comparing with the general population of ten to twenty years. If we compare the French data with the foreign one we can see that France is not in a very good situation regarding the decreasing tendency of smoking among the general practitioners and in the general population. This study justify the strengthening of the fight against smoking among adults and doctors. We remind that the very roots of the tabagism are in the youth: specific studies might take in account this core problem. PMID:8319110

  9. The reliability and validity of the Social Responsiveness Scale in a UK general child population.

    PubMed

    Wigham, Sarah; McConachie, Helen; Tandos, Jonathan; Le Couteur, Ann S

    2012-01-01

    This is the first UK study to report the reliability, validity, and factor structure of the Social Responsiveness Scale (SRS) in a general population sample. Parents of 500 children (aged 5-8 years) in North East England completed the SRS. Profiles of scores were similar to USA norms, and a single factor structure was identified. Good construct validity and internal consistency were found. Children with identified special needs were found to have significantly higher SRS scores than those without. The findings suggest the SRS performs in similar ways in UK and USA general population samples of children and can be used without modification in the UK. PMID:22277583

  10. Patients’ perception of differences in general practitioners’ attitudes toward immigrants compared to the general population: Qualicopc Slovenia

    PubMed Central

    Rotar Pavlič, Danica

    2016-01-01

    Abstract Introduction Globally, the number of immigrants is rising every year, so that the number of immigrants worldwide is estimated at 200 million. In Slovenia, immigrants comprise 6.5% of the overall population. Immigrants bring along to a foreign country their cultural differences and these differences can affect immigrants’ overall health status and lead to chronic health conditions. The aim of this study was to identify patients’ perception of general practitioners’ (GPs’) attitudes toward immigrants in Slovenia. Methods This study was based on the Qualicopc questionnaire. We used the questions that targeted patients’ experience with the appointment at their GP on the day that the study was carried out. Results There were no differences in GPs’ accessibility based on groups included in our study (p>0.05). Compared to the non-immigrant population, first-generation immigrants answered that their GPs were impolite (p=0.018) and that they did not take enough time for them (p=0.038). In addition, they also experienced more difficulties understanding their GP’s instructions (p<0.001). Second-generation immigrants experienced more negative behaviour from GPs, and first-generation immigrants had more difficulties understanding GPs’ instructions. Conclusion There may be some differences in patients’ perception of GPs’ attitudes towards immigrants in comparison with the general Slovenian population. However, based on the perception of the immigrants that do benefit from the medical care it is not possible to judge the GPs’ attitudes towards immigrants as worse compared to their attitude towards the non-immigrant population. Indeed, there may be other reasons why the patients answered the way they did. PMID:27703534

  11. Migraine and tension-type headache in a general population: psychosocial factors.

    PubMed

    Rasmussen, B K

    1992-12-01

    In a cross-sectional study of headache disorders in a representative general population, the prevalence of migraine and tension-type headache was assessed in relation to various psychosocial factors. The random sample comprised 1000 25-64 year old men and women of whom 740 attended the investigation. The headache disorders were classified on the basis of a clinical interview, a physical and a neurological examination using the operational diagnostic criteria of the International Headache Society. None of the sociodemographic variables: marital status, cohabitation, educational level, occupational category or employment status were significantly associated with migraine or tension-type headache. In the univariate analyses tension-type headache was significantly associated with a high Neuroticism score on the Eysenck Personality Questionnaire whereas migraine was not. Variables on work conditions and psychosocial factors significantly associated with the headache disorders in univariate analyses were subjected to multivariate analysis. Migraine was significantly associated with exposure to chemicals and fumes at work in women and poor self-appraisal of health in men. In the univariate analyses tension-type headache was significantly related to a series of psychosocial variables. In the multivariate analyses it remained associated with a current feeling of fatigue in both sexes, time-pressure at work in women and exposure to fumes in men.

  12. Chinese Version of the EQ-5D Preference Weights: Applicability in a Chinese General Population

    PubMed Central

    Wu, Chunmei; Gong, Yanhong; Wu, Jiang; Zhang, Shengchao; Yin, Xiaoxv; Dong, Xiaoxin; Li, Wenzhen; Cao, Shiyi; Mkandawire, Naomie; Lu, Zuxun

    2016-01-01

    Objectives This study aimed to test the reliability, validity and sensitivity of Chinese version of the EQ-5D preference weights in Chinese general people, examine the differences between the China value set and the UK, Japan and Korea value sets, and provide methods for evaluating and comparing the EQ-5D value sets of different countries. Methods A random sample of 2984 community residents (15 years or older) were interviewed using a questionnaire including the EQ-5D scale. Level of agreement, convergent validity, known-groups validity and sensitivity of the EQ-5D China, United Kingdom (UK), Japan and Korea value sets were determined. Results The mean EQ-5D index scores were significantly (P<0.05) different among the UK (0.964), Japan (0.981), Korea (0.987), and China (0.985) weights. High level of agreement (intraclass correlations coefficients > 0.75) and convergent validity (Pearson’s correlation coefficients > 0.95) were found between each paired schemes. The EQ-5D index scores discriminated equally well for the four versions between levels of 10 known-groups (P< 0.05). The effect size and the relative efficiency statistics showed that the China weights had better sensitivity. Conclusions The China EQ-5D preference weights show equivalent psychometric properties with those from the UK, Japan and Korea weights while slightly more sensitive to known group differences than those from the Japan and Korea weights. Considering both psychometric and sociocultural issues, the China scheme should be a priority as an EQ-5D based measure of the health related quality of life in Chinese general population. PMID:27711169

  13. Traffic-related air pollution and risk for leukaemia of an adult population.

    PubMed

    Raaschou-Nielsen, Ole; Ketzel, Matthias; Harbo Poulsen, Aslak; Sørensen, Mette

    2016-03-01

    Air pollution causes lung cancer, but associations with other cancers have not been established. We investigated whether long-term exposure to traffic-related air pollution is associated with the risk of the general population for leukaemia. We identified 1,967 people in whom leukaemia was diagnosed in 1992-2010 from a nation-wide cancer registry and selected 3,381 control people at random, matched on sex and year of birth, from the entire Danish population. Residential addresses since 1971 were traced in a population registry, and outdoor concentrations of NOx and NO2 , as indicators of traffic-related air pollution, were calculated at each address in a dispersion model. We used conditional logistic regression to estimate the risk for leukaemia after adjustment for income, educational level, cohabitation status and co-morbidity. In linear analyses, we found odds ratios for acute myeloid leukaemia of 1.20 (95% confidence interval: 1.04-1.38) per 20 µg/m(3) increase in NOx and 1.31 (1.02-1.68) per 10 µg/m(3) increase in NO2 , calculated as time-weighted average exposure at all addresses since 1971. We found no association with chronic myeloid or lymphocytic leukaemia. This study indicates an association between long-term exposure to traffic-related air pollution and acute myeloid leukaemia in the general population, but not for other subtypes of leukaemia.

  14. Atopic dermatitis, asthma and allergic rhinitis in general practice and the open population: a systematic review

    PubMed Central

    Pols, D. H. J.; Wartna, J. B.; Moed, H.; van Alphen, E. I.; Bohnen, A. M.; Bindels, P. J. E.

    2016-01-01

    Objective To examine whether significant differences exist between the self-reported prevalence of atopic disorders in the open population compared with physician diagnosed prevalence of atopic disorders in general practice. Methods Medline (OvidSP), PubMed Publisher, EMBASE, Google Scholar and the Cochrane Controlled Clinical Trials Register databases were systematically reviewed for articles providing data on the prevalence of asthma, allergic rhinitis and eczema in a GP setting. Studies were only included when they had a cross-sectional or cohort design and included more than 100 children (aged 0-18 years) in a general practice setting. All ISAAC studies (i.e. the open population) that geographically matched a study selected from the first search, were also included. A quality assessment was conducted. The primary outcome measures were prevalence of eczema, asthma and allergic rhinitis in children aged 0-18 years. Results The overall quality of the included studies was good. The annual and lifetime prevalences of the atopic disorders varied greatly in both general practice and the open population. On average, the prevalence of atopic disorders was higher in the open population. Conclusion There are significant differences between the self-reported prevalence of atopic disorders in the open population compared with physician diagnosed prevalence of atopic disorders in general practice. Data obtained in the open population cannot simply be extrapolated to the general practice setting. This should be taken into account when considering a research topic or requirements for policy development. GPs should be aware of the possible misclassification of allergic disorders in their practice. Key PointsEpidemiological data on atopic disorders in children can be obtained from various sources, each having its own advantages and limitations.On average, the prevalence of atopic disorders is higher in the open population.GPs should take into account the possible

  15. Bianchi Type VI0 Inflationary Cosmological Model in General Relativity

    NASA Astrophysics Data System (ADS)

    Bali, Raj; Poonia, Laxmi

    Bianchi Type VI0 inflationary cosmological model with flat potential in General Relativity, is investigated. To get the deterministic solution in terms of cosmic time t, we assume that σ (shear) is proportional to expansion (θ) where σ = {1 / {√ 3 }}t( {{{{A}{4} } / {A}} - {{{B}{4} } / {B}}}), θ = {{{A}{4} } / {A}} + {{{2B}{4} } / {B}}. Thus {{σ / θ } = constant}, leads to A = Bn where A and B are metric potentials and n is a constant. We find that spatial volume increases with time. Hence inflationary scenario exists in the model. Since {σ / θ } != 0 in general. Thus the model represents anisotropic universe throughout. However, if l = {1 / {{4k}}} then the model isotropizes. This result matches with astronomical observations. The model represents decelerating and late time acceleration which matches with recent astronomical observations Riess et al. [29], Perlmutter et al. [30]. The model has Point Type singularity at τ = {1 / α }{sin}{ - 1} ({{1 / {{2k}}}} ) (MacCallum [31]). The rate of Higg’s field (φ) decreases with time.

  16. The Gravity Probe B test of general relativity

    NASA Astrophysics Data System (ADS)

    Everitt, C. W. F.; Muhlfelder, B.; DeBra, D. B.; Parkinson, B. W.; Turneaure, J. P.; Silbergleit, A. S.; Acworth, E. B.; Adams, M.; Adler, R.; Bencze, W. J.; Berberian, J. E.; Bernier, R. J.; Bower, K. A.; Brumley, R. W.; Buchman, S.; Burns, K.; Clarke, B.; Conklin, J. W.; Eglington, M. L.; Green, G.; Gutt, G.; Gwo, D. H.; Hanuschak, G.; He, X.; Heifetz, M. I.; Hipkins, D. N.; Holmes, T. J.; Kahn, R. A.; Keiser, G. M.; Kozaczuk, J. A.; Langenstein, T.; Li, J.; Lipa, J. A.; Lockhart, J. M.; Luo, M.; Mandel, I.; Marcelja, F.; Mester, J. C.; Ndili, A.; Ohshima, Y.; Overduin, J.; Salomon, M.; Santiago, D. I.; Shestople, P.; Solomonik, V. G.; Stahl, K.; Taber, M.; Van Patten, R. A.; Wang, S.; Wade, J. R.; Worden, P. W., Jr.; Bartel, N.; Herman, L.; Lebach, D. E.; Ratner, M.; Ransom, R. R.; Shapiro, I. I.; Small, H.; Stroozas, B.; Geveden, R.; Goebel, J. H.; Horack, J.; Kolodziejczak, J.; Lyons, A. J.; Olivier, J.; Peters, P.; Smith, M.; Till, W.; Wooten, L.; Reeve, W.; Anderson, M.; Bennett, N. R.; Burns, K.; Dougherty, H.; Dulgov, P.; Frank, D.; Huff, L. W.; Katz, R.; Kirschenbaum, J.; Mason, G.; Murray, D.; Parmley, R.; Ratner, M. I.; Reynolds, G.; Rittmuller, P.; Schweiger, P. F.; Shehata, S.; Triebes, K.; VandenBeukel, J.; Vassar, R.; Al-Saud, T.; Al-Jadaan, A.; Al-Jibreen, H.; Al-Meshari, M.; Al-Suwaidan, B.

    2015-11-01

    The Gravity Probe B mission provided two new quantitative tests of Einstein’s theory of gravity, general relativity (GR), by cryogenic gyroscopes in Earth’s orbit. Data from four gyroscopes gave a geodetic drift-rate of -6601.8 ± 18.3 marc-s yr-1 and a frame-dragging of -37.2 ± 7.2 marc-s yr-1, to be compared with GR predictions of -6606.1 and -39.2 marc-s yr-1 (1 marc-s = 4.848 × 10-9 radians). The present paper introduces the science, engineering, data analysis, and heritage of Gravity Probe B, detailed in the accompanying 20 CQG papers.

  17. CPT symmetry and antimatter gravity in general relativity

    NASA Astrophysics Data System (ADS)

    Villata, M.

    2011-04-01

    The gravitational behavior of antimatter is still unknown. While we may be confident that antimatter is self-attractive, the interaction between matter and antimatter might be either attractive or repulsive. We investigate this issue on theoretical grounds. Starting from the CPT invariance of physical laws, we transform matter into antimatter in the equations of both electrodynamics and gravitation. In the former case, the result is the well-known change of sign of the electric charge. In the latter, we find that the gravitational interaction between matter and antimatter is a mutual repulsion, i.e. antigravity appears as a prediction of general relativity when CPT is applied. This result supports cosmological models attempting to explain the Universe accelerated expansion in terms of a matter-antimatter repulsive interaction.

  18. Cosmological perturbations of unimodular gravity and general relativity are identical

    NASA Astrophysics Data System (ADS)

    Basak, Abhishek; Fabre, Ophélia; Shankaranarayanan, S.

    2016-10-01

    Unimodular gravity (UG) is a restricted version of general relativity (GR) in which the variation of the metric determinant is set to zero and the field equations are given by the trace-free part of the full Einstein equations. The background equations in UG and GR are identical. It was recently claimed that the first order contribution in the temperature fluctuations of the Cosmic Microwave Background (CMB) in UG is different from GR. In this work, we calculate the first order perturbation equations in UG and show that the Sachs-Wolfe effect in UG, in terms of gauge invariant variables, is identical to GR. We also show that the second order perturbation equation of Mukhanov-Sasaki variable in UG, is identical to GR. The only difference comes from the gauge choices due the constraint on the metric determinant. Hence, UG and GR are identical and indistinguishable in CMB data on large scales.

  19. Ambiguous tests of general relativity on cosmological scales

    SciTech Connect

    Zuntz, Joe; Baker, Tessa; Ferreira, Pedro G.; Skordis, Constantinos E-mail: tessa.baker@astro.ox.ac.uk E-mail: skordis@nottingham.ox.ac.uk

    2012-06-01

    There are a number of approaches to testing General Relativity (GR) on linear scales using parameterized frameworks for modifying cosmological perturbation theory. It is sometimes assumed that the details of any given parameterization are unimportant if one uses it as a diagnostic for deviations from GR. In this brief report we argue that this is not necessarily so. First we show that adopting alternative combinations of modifications to the field equations significantly changes the constraints that one obtains. In addition, we show that using a parameterization with insufficient freedom significantly tightens the apparent theoretical constraints. Fundamentally we argue that it is almost never appropriate to consider modifications to the perturbed Einstein equations as being constraints on the effective gravitational constant, for example, in the same sense that solar system constraints are. The only consistent modifications are either those that grant near-total freedom, as in decomposition methods, or ones which map directly to a particular part of theory space.

  20. General Relativity and Cosmology: Unsolved Questions and Future Directions

    NASA Astrophysics Data System (ADS)

    Debono, Ivan; Smoot, George F.

    2016-09-01

    For the last 100 years, General Relativity (GR) has taken over the gravitational theory mantle held by Newtonian Gravity for the previous 200 years. This article reviews the status of GR in terms of its self-consistency, completeness, and the evidence provided by observations, which have allowed GR to remain the champion of gravitational theories against several other classes of competing theories. We pay particular attention to the role of GR and gravity in cosmology, one of the areas in which one gravity dominates and new phenomena and effects challenge the orthodoxy. We also review other areas where there are likely conflicts pointing to the need to replace or revise GR to represent correctly observations and consistent theoretical framework. Observations have long been key both to the theoretical liveliness and viability of GR.We conclude with a discussion of the likely developments over the next 100 years.

  1. General relativity as an attractor for scalar-torsion cosmology

    NASA Astrophysics Data System (ADS)

    Järv, Laur; Toporensky, Alexey

    2016-01-01

    We study flat Friedmann-Lemaître-Robertson-Walker cosmological models for a scalar field coupled nonminimally to teleparallel gravity with generic coupling and potential functions. The goal in this paper is to determine the conditions under which cosmological evolution tends to the limit where the variation of the gravitational "constant" ceases and the system evolves close to general relativity (GR). These conditions can be read off from the approximate analytical solutions describing the process in matter and potential domination eras. Only those models where the GR limit exists and is an attractor can be considered viable. We expect the results to hold in the original "pure tetrad" formulation as well as in the recently suggested covariant formulation of the teleparallel theory. In the former case the GR attractor simultaneously provides a mechanism for how cosmological evolution suppresses the problematic degrees of freedom stemming from the lack of local Lorentz invariance.

  2. Collapse of magnetized hypermassive neutron stars in general relativity.

    PubMed

    Duez, Matthew D; Liu, Yuk Tung; Shapiro, Stuart L; Shibata, Masaru; Stephens, Branson C

    2006-01-27

    Hypermassive neutron stars (HMNSs)--equilibrium configurations supported against collapse by rapid differential rotation--are possible transient remnants of binary neutron-star mergers. Using newly developed codes for magnetohydrodynamic simulations in dynamical spacetimes, we are able to track the evolution of a magnetized HMNS in full general relativity for the first time. We find that secular angular momentum transport due to magnetic braking and the magnetorotational instability results in the collapse of an HMNS to a rotating black hole, accompanied by a gravitational wave burst. The nascent black hole is surrounded by a hot, massive torus undergoing quasistationary accretion and a collimated magnetic field. This scenario suggests that HMNS collapse is a possible candidate for the central engine of short gamma-ray bursts.

  3. A general modeling framework for genome ancestral origins in multiparental populations.

    PubMed

    Zheng, Chaozhi; P Boer, Martin; van Eeuwijk, Fred A

    2014-09-01

    The next generation of QTL (quantitative trait loci) mapping populations have been designed with multiple founders, where one to a number of generations of intercrossing are introduced prior to the inbreeding phase to increase accumulated recombinations and thus mapping resolution. Examples of such populations are Collaborative Cross (CC) in mice and Multiparent Advanced Generation Inter-Cross (MAGIC) lines in Arabidopsis. The genomes of the produced inbred lines are fine-grained random mosaics of the founder genomes. In this article, we present a novel framework for modeling ancestral origin processes along two homologous autosomal chromosomes from mapping populations, which is a major component in the reconstruction of the ancestral origins of each line for QTL mapping. We construct a general continuous time Markov model for ancestral origin processes, where the rate matrix is deduced from the expected densities of various types of junctions (recombination breakpoints). The model can be applied to monoecious populations with or without self-fertilizations and to dioecious populations with two separate sexes. The analytic expressions for map expansions and expected junction densities are obtained for mapping populations that have stage-wise constant mating schemes, such as CC and MAGIC. Our studies on the breeding design of MAGIC populations show that the intercross mating schemes do not matter much for large population size and that the overall expected junction density, and thus map resolution, are approximately proportional to the inverse of the number of founders.

  4. A New Screening Programme for Autism in a General Population of Swedish Toddlers

    ERIC Educational Resources Information Center

    Nygren, Gudrun; Sandberg, Eva; Gillstedt, Fredrik; Ekeroth, Gunnar; Arvidsson, Thomas; Gillberg, Christopher

    2012-01-01

    The evidence from early intervention studies of autism has emphasised the need for early diagnosis. Insight into the early presentation of autism is crucial for early recognition, and routine screening can optimise the possibility for early diagnosis. General population screening was conducted for 2.5-year-old children at child health centres in…

  5. Patients Taking Imatinib for CML Have Similar Risk of Death as General Population

    Cancer.gov

    In an international study, the risk of death for chronic myelogenous leukemia patients treated with imatinib (Gleevec) who had been in remission for at least 2 years was not different from that of the general population, according to an article in the March 21, 2011 issue of the Journal of the National Cancer Institute.

  6. The Reliability and Validity of the Social Responsiveness Scale in a UK General Child Population

    ERIC Educational Resources Information Center

    Wigham, Sarah; McConachie, Helen; Tandos, Jonathan; Le Couteur, Ann S.

    2012-01-01

    This is the first UK study to report the reliability, validity, and factor structure of the Social Responsiveness Scale (SRS) in a general population sample. Parents of 500 children (aged 5-8 years) in North East England completed the SRS. Profiles of scores were similar to USA norms, and a single factor structure was identified. Good construct…

  7. Comparison of chronic analgesic drugs prevalence in Parkinson's disease, other chronic diseases and the general population.

    PubMed

    Brefel-Courbon, Christine; Grolleau, Sabrina; Thalamas, Claire; Bourrel, Robert; Allaria-Lapierre, Valérie; Loï, Robert; Micallef-Roll, Joelle; Lapeyre-Mestre, Maryse

    2009-01-01

    Patients with Parkinson's disease (PD) frequently experienced pain. Nevertheless, there are no epidemiological data about frequency of pain in PD. We compare pain prevalence using analgesic prescription in PD patients, in the general population and in two samples of painful patients: diabetics and osteoarthritis patients in France. Data were obtained from the French System of Health Insurance for the year 2005. Medications (antiparkinsonian, antidiabetics drugs and osteoarthritis drugs) were used for identification of PD, diabetic and osteoarthritis patients. We estimated the prevalence of analgesic drugs prescription (at least one analgesic drug) and the prevalence of chronic analgesic drugs prescription (more than 90 DDD of analgesic drug). The study included 11,466 PD patients. PD patients significantly received more prescription of analgesics than the general population (82% versus 77%,) and fewer than patients with osteoarthritis (82% versus 90%). No significant difference was found between PD and diabetic patients. The chronic prescription of analgesic drugs was more prevalent in PD patients (33%) than in the general population (20%) and in diabetic patients (26%) and similar to that in osteoarthritis patients. PD patients were more exposed than the general population and diabetics to opiates, acetaminophen, and adjuvant analgesics chronic use.

  8. RESIDUES AND METABOLITES OF SELECTED PERSISTENT HALOGENATED HYDROCARBONS IN BLOOD SPECIMENS FROM A GENERAL POPULATION SURVEY

    EPA Science Inventory

    The National Center for Health Statistics collaborated with the National Human Monitoring Program of the U.S. Environmental Protection Agency (EPA) in a four-year study to assess the exposure of the general population to selected pesticides through analysis of blood serum and uri...

  9. DEARS Particulate Matter Relationships for Personal, Indoor, Outdoor, and Central Site Settings for a General Population

    EPA Science Inventory

    This analysis provides the initial summary of PM2.5 mass concentrations relationships for all seasons and participants for a general population in the Detroit Exposure and Aerosol Research Study (DEARS). The summary presented highlights the utility of the new methodol...

  10. The relationship between general population suicide rates and the Internet: a cross-national study.

    PubMed

    Shah, Ajit

    2010-04-01

    Internet Web sites and chat rooms have been reported both to promote suicides and have a positive beneficial effect on suicidal individuals. There is a paucity of studies examining the role of the Internet in general population suicide rates. The relationship between general population suicide rates and the prevalence of Internet users was examined in a cross-national study using data from the World Health Organization and the United Nations Web sites. The prevalence of Internet users was significantly and positively correlated with general population suicide rates in both sexes. On multiple regression analysis the prevalence of Internet users was independently associated with general population suicide rates in males, and this independent relationship in females approached statistical significance. Caution should be exercised in the attribution of a causal relationship and the direction of this relationship because of the cross-sectional and ecological study design whereby the findings are subject to ecological fallacy. However, the findings identify and support a need for further research. PMID:20465349

  11. The Value of a College Degree for Foster Care Alumni: Comparisons with General Population Samples

    ERIC Educational Resources Information Center

    Salazar, Amy M.

    2013-01-01

    Higher education is associated with substantial adult life benefits, including higher income and improved quality of life, among others. The current study compared adult outcomes of 250 foster care alumni college graduates with two samples of general population graduates to explore the role higher education plays in these young adults' lives.…

  12. Seroepidemiology of Toxoplasma gondii infection in general population in a Northern Mexican city

    Technology Transfer Automated Retrieval System (TEKTRAN)

    There is a lack of information about the seroepidemiology of T. gondii infection in the general population of Durango City, Mexico. Anti-T. gondii IgG and IgM antibodies were sought in 974 inhabitants in Durango City, Mexico using enzyme-linked immunoassays. In total, 59 (6.1%) of 974 participants (...

  13. Proof of a new area law in general relativity

    NASA Astrophysics Data System (ADS)

    Bousso, Raphael; Engelhardt, Netta

    2015-08-01

    A future holographic screen is a hypersurface of indefinite signature, foliated by marginally trapped surfaces with area A (r ). We prove that A (r ) grows strictly monotonically. Future holographic screens arise in gravitational collapse. Past holographic screens exist in our own Universe; they obey an analogous area law. Both exist more broadly than event horizons or dynamical horizons. Working within classical general relativity, we assume the null curvature condition and certain generiticity conditions. We establish several nontrivial intermediate results. If a surface σ divides a Cauchy surface into two disjoint regions, then a null hypersurface N that contains σ splits the entire spacetime into two disjoint portions: the future-and-interior, K+; and the past-and-exterior, K-. If a family of surfaces σ (r ) foliate a hypersurface, while flowing everywhere to the past or exterior, then the future-and-interior K+(r ) grows monotonically under inclusion. If the surfaces σ (r ) are marginally trapped, we prove that the evolution must be everywhere to the past or exterior, and the area theorem follows. A thermodynamic interpretation as a second law is suggested by the Bousso bound, which relates A (r ) to the entropy on the null slices N (r ) foliating the spacetime. In a companion letter, we summarize the proof and discuss further implications.

  14. EQ-5D-5L in the General German Population: Comparison and Evaluation of Three Yearly Cross-Section Surveys.

    PubMed

    Huber, Manuel B; Reitmeir, Peter; Vogelmann, Martin; Leidl, Reiner

    2016-03-21

    Health-related quality of life (HRQoL) is a key measure for evaluating health status in populations. Using the recent EQ-5D-5L for measurement, this study analyzed quality of life results and their stability over consecutive population surveys. Three cross-section surveys for representative samples of the general German population from 2012, 2013, and 2014 were evaluated using the EQ-5D-5L descriptive system and valuation by the Visual Analog Scale (VAS). Aggregated sample size reached 6074. The dimension with the highest prevalence of problems was pain/discomfort (31.7%). Compared with 2012 (59.3%), the percentage of participants in the best health state increased slightly in 2013 (63.4%) and 2014 (62%). Over the 3-year period, diabetes and heart disease had the strongest negative influence on mean VAS result. The number of reported chronic diseases cumulatively reduced mean VAS. Extreme problems in one or more dimensions were stated by only 0.1%-0.2% of patients. Of the potential 247 health states with a problem score ≥ 20, only six were observed in the aggregated sample. HRQoL results were fairly stable over the 3 years, but the share of the population with no problems was not. Results from the aggregated sample may serve as updated reference values for the general German population.

  15. Origins and development of the Cauchy problem in general relativity

    NASA Astrophysics Data System (ADS)

    Ringström, Hans

    2015-06-01

    The seminal work of Yvonne Choquet-Bruhat published in 1952 demonstrates that it is possible to formulate Einstein's equations as an initial value problem. The purpose of this article is to describe the background to and impact of this achievement, as well as the result itself. In some respects, the idea of viewing the field equations of general relativity as a system of evolution equations goes back to Einstein himself; in an argument justifying that gravitational waves propagate at the speed of light, Einstein used a special choice of coordinates to derive a system of wave equations for the linear perturbations on a Minkowski background. Over the following decades, Hilbert, de Donder, Lanczos, Darmois and many others worked to put Einstein's ideas on a more solid footing. In fact, the issue of local uniqueness (giving a rigorous justification for the statement that the speed of propagation of the gravitational field is bounded by that of light) was already settled in the 1930s by the work of Stellmacher. However, the first person to demonstrate both local existence and uniqueness in a setting in which the notion of finite speed of propagation makes sense was Yvonne Choquet-Bruhat. In this sense, her work lays the foundation for the formulation of Einstein's equations as an initial value problem. Following a description of the results of Choquet-Bruhat, we discuss the development of three research topics that have their origin in her work. The first one is local existence. One reason for addressing it is that it is at the heart of the original paper. Moreover, it is still an active and important research field, connected to the problem of characterizing the asymptotic behaviour of solutions that blow up in finite time. As a second topic, we turn to the questions of global uniqueness and strong cosmic censorship. These questions are of fundamental importance to anyone interested in justifying that the Cauchy problem makes sense globally. They are also closely

  16. Evaluation of general response patterns as a diagnostic tool to determining contaminant impacts on fish populations

    SciTech Connect

    Jaworska, J.S.; Barnthouse, L.W.; Rose, K.A.

    1995-12-31

    Five General Response Patterns by fish populations exposed to stress were hypothesized by P. Colby and K. Munkittrick and D. Dixon. The authors used an individual based model of walleye and yellow perch configured for Oneida Lake, NY to test the generality of these patterns. They compared the yellow perch population responses in mean age, size at age, fraction mature at age, individual fecundity and density under 5 stress conditions. The stresses imposed were: (1) adults mortality; (2) eggs mortality (3) metabolic impacts on juveniles; (4) indirect effects from predator level -- increased predator mortality; (5) indirect effects form prey level -- reduced carrying capacity. Modeled yellow perch responses different from the responses hypothesized by Colby/Munkittrick and Dixon. Their analysis shows that the strength of predator-prey coupling must be considered when using patterns of growth, mortality and reproduction to infer the identity of stressors influencing fish populations.

  17. Prevalence of Contact Allergy to p-Phenylenediamine in the European General Population.

    PubMed

    Diepgen, Thomas L; Naldi, Luigi; Bruze, Magnus; Cazzaniga, Simone; Schuttelaar, Marie-Louise; Elsner, Peter; Goncalo, Margarida; Ofenloch, Robert; Svensson, Åke

    2016-02-01

    Population-based studies on contact allergy to p-phenylenediamine (PPD) are scarce. A cross-sectional study was performed to assess the prevalence of contact allergy to PPD and its risk factors in the general population of 5 European countries. A total of 10,425 subjects were interviewed, and a random sample (n = 2,739) was patch tested to PPD. Overall, 5,286 individuals (50.9%) reported having used hair colorants at least once in their lifetime (78% female, 20% male), and 35% had used hair colorants during the last 12 months. Hair colorant avoidance because of any skin problem during the lifetime was reported by 6%. Black henna tattoos had been used by 5.5% during their lifetime. The prevalence of PPD contact allergy was 0.8% (95% confidence interval 0.6-1.0%), with no statistically significant association with gender or hair dye use. The prevalence of PPD in black henna tattoo users was 3.2% versus 0.6% in nonusers (P < 0.001). A clinically relevant positive patch test reaction to PPD related to hair coloring products was found in 0.1% (95% confidence interval 0.0-0.2%). A significant association with PPD contact allergy was observed for subjects who had black henna tattoos in their lifetime, with an age- and gender-adjusted odds ratio of 9.33 (95% confidence interval 3.45-25.26, P < 0.001). Black henna tattoos are an important risk factor for PPD contact allergy. PMID:26802237

  18. Prevalence of Pulmonary Hypertension in the General Population: The Rotterdam Study

    PubMed Central

    Moreira, Eduardo M.; Gall, Henning; Leening, Maarten J. G.; Lahousse, Lies; Loth, Daan W.; Krijthe, Bouwe P.; Kiefte-de Jong, Jessica C.; Brusselle, Guy G.; Hofman, Albert; Stricker, Bruno H.; Ghofrani, Hossein A.; Franco, Oscar H.; Felix, Janine F.

    2015-01-01

    Background Pulmonary hypertension is characterized by increased pulmonary artery pressure and carries an increased mortality. Population-based studies into pulmonary hypertension are scarce and little is known about its prevalence in the general population. We aimed to describe the distribution of echocardiographically-assessed pulmonary artery systolic pressure (ePASP) in the general population, to estimate the prevalence of pulmonary hypertension, and to identify associated factors. Methods Participants (n = 3381, mean age 76.4 years, 59% women) from the Rotterdam Study, a population-based cohort, underwent echocardiography. Echocardiographic pulmonary hypertension was defined as ePASP>40 mmHg. Results Mean ePASP was 26.3 mmHg (SD 7.0). Prevalence of echocardiographic pulmonary hypertension was 2.6% (95%CI: 2.0; 3.2). Prevalence was higher in older participants compared to younger ones (8.3% in those over 85 years versus 0.8% in those between 65 and 70), and in those with underlying disorders versus those without (5.9% in subjects with COPD versus 2.3%; 9.2% in those with left ventricular systolic dysfunction versus 2.3%; 23.1% in stages 3 or 4 left ventricular diastolic dysfunction versus 1.9% in normal or stage 1). Factors independently associated with higher ePASP were older age, higher BMI, left ventricular diastolic dysfunction, COPD and systemic hypertension. Conclusion In this large population-based study, we show that pulmonary hypertension as measured by echocardiography has a low prevalence in the overall general population in the Netherlands, but estimates may be higher in specific subgroups, especially in those with underlying diseases. Increased pulmonary arterial pressure is likely to gain importance in the near future due to population aging and the accompanying prevalences of underlying disorders. PMID:26102085

  19. Cosmological General Relativity with Scale Factor and Dark Energy

    NASA Astrophysics Data System (ADS)

    Oliveira, Firmin J.

    2014-11-01

    In this paper the four-dimensional (4-D) space-velocity Cosmological General Relativity of Carmeli is developed by a general solution of the Einstein field equations. The Tolman metric is applied in the form where g μν is the metric tensor. We use comoving coordinates x α = ( x 0, x 1, x 2, x 3) = ( τv, r, θ, ϕ), where τ is the Hubble-Carmeli time constant, v is the universe expansion velocity and r, θ and ϕ are the spatial coordinates. We assume that μ and R are each functions of the coordinates τv and r. The vacuum mass density ρ Λ is defined in terms of a cosmological constant Λ, where the Carmeli gravitational coupling constant κ = 8 πG/ c 2 τ 2, where c is the speed of light in vacuum. This allows the definitions of the effective mass density and effective pressure where ρ is the mass density and p is the pressure. Then the energy-momentum tensor where u μ = (1,0,0,0) is the 4-velocity. The Einstein field equations are taken in the form where R μν is the Ricci tensor, κ = 8 πG/ c 2 τ 2 is Carmeli's gravitation constant, where G is Newton's constant and the trace T = g αβ T αβ . By solving the field equations (6) a space-velocity cosmology is obtained analogous to the Friedmann-Lemaître-Robertson-Walker space-time cosmology. We choose an equation of state such that with an evolving state parameter where R v = R v ( v) is the scale factor and w 0 and w a are constants. Carmeli's 4-D space-velocity cosmology is derived as a special case.

  20. Some Bianchi type generalized ghost piligrim dark energy models in general relativity

    NASA Astrophysics Data System (ADS)

    Santhi, M. Vijaya; Aditya, Y.; Rao, V. U. M.

    2016-04-01

    In this paper, we consider Bianchi type-III, V and VI0 space-times filled with generalized ghost pilgrim dark energy (GGPDE) in general relativity. Here we assume the anisotropic distribution of GGPDE by introducing skewness parameters. To get deterministic solutions, we consider the scale factor a(t)=(tnet)^{ 1/k}, so called hybrid expansion, which yields a time dependent deceleration parameter, and exhibits a transition of the Universe from early decelerated phase to the recent accelerating phase. To describe the behavior of the obtained models we construct equation of state (ω_{Λ}), squared sound speed (vs2) parameters and ω_{Λ}-dot{ω }_{Λ}, r-s planes. It is worth mentioning here that the analysis of evolution parameters supports the concept of pilgrim dark energy (PDE). Also, these models remain stable for PDE parameter β =-0.5. Moreover, the cosmological planes correspond to Λ CDM limit as well as different well-known dark energy models.

  1. Symptom patterns in dissociative identity disorder patients and the general population.

    PubMed

    Ross, Colin A; Ness, Laura

    2010-01-01

    The authors used the Dissociative Disorders Interview Schedule to compare structured interview symptom patterns in a general population sample (N= 502) and a sample of patients with clinical diagnoses of dissociative identity disorder (N= 303). Based on the Trauma Model, the authors predicted that the patterns would be similar in the 2 samples and that symptom scores would be higher in participants reporting childhood sexual abuse in both samples. They predicted that symptom scores would be higher among women with dissociative identity disorder reporting sexual abuse than among women in the general population reporting sexual abuse, with the clinical sample reporting more severe abuse. These predictions were supported by the data. The authors conclude that symptom patterns in dissociative identity disorder are typical of the normal human response to severe, chronic childhood trauma and have ecological validity for the human race in general.

  2. Anisotropic generalization of Matese & Whitman solution for compact star models in general relativity

    NASA Astrophysics Data System (ADS)

    Dayanandan, Baiju; Maurya, S. K.; Gupta, Y. K.; Smitha, T. T.

    2016-05-01

    We present a detailed investigation of the stability of anisotropic compact star models by introducing Matese and Whitman (Phys. Rev. D 11:1270, 1980) solution in general relativity. We have particularly looked into the detailed investigation of the measurements of basic physical parameters such as radial pressure, tangential pressure, energy density, red shift, sound velocity, masses and radii are affected by unknown effects such as loss, accretion and diffusion of mass. Those give insight into the characteristics of the compact astrophysical object with anisotropic matter distribution as well as the physical reality. The results obtained for the physical feature of compact stars such as, Her. X-1, RXJ 1856-37, SAX J1808.4-3658(SS2) and SAX J1808.4-3658(SS1) are compared to the recently observed massive compact object.

  3. Measures of relative fitness of social behaviors in finite structured population models.

    PubMed

    Tarnita, Corina E; Taylor, Peter D

    2014-10-01

    How should we measure the relative selective advantage of different behavioral strategies? The various approaches to this question have fallen into one of the following categories: the fixation probability of a mutant allele in a wild type population, some measures of gene frequency and gene frequency change, and a formulation of the inclusive fitness effect. Countless theoretical studies have examined the relationship between these approaches, and it has generally been thought that, under standard simplifying assumptions, they yield equivalent results. Most of this theoretical work, however, has assumed homogeneity of the population interaction structure--that is, that all individuals are equivalent. We explore the question of selective advantage in a general (heterogeneous) population and show that, although appropriate measures of fixation probability and gene frequency change are equivalent, they are not, in general, equivalent to the inclusive fitness effect. The latter does not reflect effects of selection acting via mutation, which can arise on heterogeneous structures, even for low mutation. Our theoretical framework provides a transparent analysis of the different biological factors at work in the comparison of these fitness measures and suggests that their theoretical and empirical use needs to be revised and carefully grounded in a more general theory.

  4. Incidence rates of in-hospital carpal tunnel syndrome in the general population and possible associations with marital status

    PubMed Central

    Mattioli, Stefano; Baldasseroni, Alberto; Curti, Stefania; Cooke, Robin MT; Bena, Antonella; de Giacomi, Giovanna; dell'Omo, Marco; Fateh-Moghadam, Pirous; Melani, Carla; Biocca, Marco; Buiatti, Eva; Campo, Giuseppe; Zanardi, Francesca; Violante, Francesco S

    2008-01-01

    Background Carpal tunnel syndrome (CTS) is a socially relevant condition associated with biomechanical risk factors. We evaluated age-sex-specific incidence rates of in-hospital cases of CTS in central/northern Italy and explored relations with marital status. Methods Seven regions were considered (overall population, 14.9 million) over 3–6-year periods between 1997 and 2002 (when out-of-hospital CTS surgery was extremely rare). Incidence rates of in-hospital cases of CTS were estimated based on 1) codified demographic, diagnostic and intervention data in obligatory discharge records from all Italian public/private hospitals, archived (according to residence) on regional databases; 2) demographic general population data for each region. We compared (using the χscore test) age-sex-specific rates between married, unmarried, divorced and widowed subsets of the general population. We calculated standardized incidence ratios (SIRs) for married/unmarried men and women. Results Age-standardized incidence rates (per 100,000 person-years) of in-hospital cases of CTS were 166 in women and 44 in men (106 overall). Married subjects of both sexes showed higher age-specific rates with respect to unmarried men/women. SIRs were calculated comparing married vs unmarried rates of both sexes: 1.59 (95% confidence interval [95% CI], 1.57–1.60) in women, and 1.42 (95% CI, 1.40–1.45) in men. As compared with married women/men, widows/widowers both showed 2–3-fold higher incidence peaks during the fourth decade of life (beyond 50 years of age, widowed subjects showed similar trends to unmarried counterparts). Conclusion This large population-based study illustrates distinct age-related trends in men and women, and also raises the question whether marital status could be associated with CTS in the general population. PMID:18957090

  5. Untreated hypertension in the UK household population - Who are missed by the general health checks?

    PubMed

    Petersen, Jakob; Benzeval, Michaela

    2016-12-01

    Hypertension is an age-related, long-term condition and a leading risk factor for premature death and disability worldwide. Due to its asymptomatic nature it can often be left undiagnosed. Long-term treatment is available, but blood pressure can also be reduced through health behaviour changes in weight control, smoking cessation, higher physical activity levels, reduced salt and alcohol intake, and healthful diets if discovered early. This paper investigates the prevalence and characteristics of those with untreated (compared to treated) hypertension who did not have a history of cardiovascular disease (CVD); a group who is in effect missed by general health checks. Untreated hypertension was studied in 8933 individuals aged 40-74 years representative of the UK household population, who were interviewed and underwent a physical health examination in their home, 2010-2012. The prevalence of untreated hypertension without a history of CVD was 7% for men, 2% for women, and 5% overall. Untreated hypertension was particularly high among the 55-64 year age group. Age and sex-adjusted analyses found strong positive associations with male gender, smoking, self-reported good-excellent health, full fat dairy preference, white bread preference, higher alcohol consumption, and living alone. Strong negative associations were found for possessing 5 + prescription drugs, statins or antiplatelets, being diagnosed with diabetes or possessing antidiabetics, and long-term limiting illness status. Notably, many reported their health as good to excellent. A fact which emphasises the importance of motivating individuals to take part in the general health checks for an asymptomatic condition such as hypertension. PMID:27413665

  6. General population job exposure matrix applied to a pooled study of prevalent carpal tunnel syndrome.

    PubMed

    Dale, Ann Marie; Zeringue, Angelique; Harris-Adamson, Carisa; Rempel, David; Bao, Stephen; Thiese, Matthew S; Merlino, Linda; Burt, Susan; Kapellusch, Jay; Garg, Arun; Gerr, Fred; Hegmann, Kurt T; Eisen, Ellen A; Evanoff, Bradley

    2015-03-15

    A job exposure matrix may be useful for the study of biomechanical workplace risk factors when individual-level exposure data are unavailable. We used job title-based exposure data from a public data source to construct a job exposure matrix and test exposure-response relationships with prevalent carpal tunnel syndrome (CTS). Exposures of repetitive motion and force from the Occupational Information Network were assigned to 3,452 active workers from several industries, enrolled between 2001 and 2008 from 6 studies. Repetitive motion and force exposures were combined into high/high, high/low, and low/low exposure groupings in each of 4 multivariable logistic regression models, adjusted for personal factors. Although force measures alone were not independent predictors of CTS in these data, strong associations between combined physical exposures of force and repetition and CTS were observed in all models. Consistent with previous literature, this report shows that workers with high force/high repetition jobs had the highest prevalence of CTS (odds ratio = 2.14-2.95) followed by intermediate values (odds ratio = 1.09-2.27) in mixed exposed jobs relative to the lowest exposed workers. This study supports the use of a general population job exposure matrix to estimate workplace physical exposures in epidemiologic studies of musculoskeletal disorders when measures of individual exposures are unavailable. PMID:25700886

  7. Prevalence of bulimic behaviors and bulimia among a sample of the general population.

    PubMed

    Warheit, G J; Langer, L M; Zimmerman, R S; Biafora, F A

    1993-03-01

    Data are presented on the prevalence of bulimic symptoms and bulimia among a sample of adults residing in north-central Florida (n = 2,075). The data were gathered between 1984 and 1986. The sample included 1,736 whites and 339 blacks, of whom 1,040 were females and 1,035 were males. A current diagnosis of bulimia was made using the criteria of the Diagnostic and Statistical Manual, Third Edition (DSM-III), of the American Psychiatric Association. Females had significantly higher rates than did males on nine of the 10 bulimic symptoms. Blacks had symptom rates equal to or greater than whites on eight of the 10 items, and those in the lowest socioeconomic groups (SES) had rates greater than those in the highest SES group on nine of the 10 symptoms. Eight persons, 0.4% of the total sample, met the DSM-III criteria for a diagnosis of bulimia. These included six white females and two black males. Five of the females were aged 18-29 years; one was over 45. Five of the females were in the lower middle SES group; one was in the upper middle SES group. Both of the black males were aged 30-44, and both were in the lowest SES group. The data emphasize the need to distinguish between bulimic type symptoms and bulimia when estimating the prevalence of eating-related problems in the general population. PMID:8465808

  8. Rates and characteristics of sleep paralysis in the general population of Denmark and Egypt.

    PubMed

    Jalal, Baland; Hinton, Devon E

    2013-09-01

    In the current research we report data from two studies that examined rates and characteristics of sleep paralysis (SP) in the general population of Denmark and Egypt. In Study I, individuals from Denmark and Egypt did not differ in age whereas there were more males in the Egyptian sample (47 vs. 64 %); in Study II, individuals from Denmark and Egypt were comparable in terms of age and gender distribution. In Study I we found that significantly fewer individuals had experienced SP in Denmark [25 % (56/223)] than in Egypt [44 % (207/470)] p < .001. In Study II we found that individuals who had experienced at least one lifetime episode of SP from Denmark (n = 58) as compared to those from Egypt (n = 143) reported significantly fewer SP episodes in a lifetime relative to SP experiencers from Egypt (M = 6.0 vs. M = 19.4, p < .001). SP in the Egyptian sample was characterized by high rates of SP (as compared to in Denmark), frequent occurrences (three times that in the Denmark sample), prolonged immobility during SP, and great fear of dying from the experience. In addition, in Egypt, believing SP to be precipitated by the supernatural was associated with fear of the experience and longer SP immobility. Findings are discussed in the context of cultural elaboration and salience theories of SP.

  9. Rates and characteristics of sleep paralysis in the general population of Denmark and Egypt.

    PubMed

    Jalal, Baland; Hinton, Devon E

    2013-09-01

    In the current research we report data from two studies that examined rates and characteristics of sleep paralysis (SP) in the general population of Denmark and Egypt. In Study I, individuals from Denmark and Egypt did not differ in age whereas there were more males in the Egyptian sample (47 vs. 64 %); in Study II, individuals from Denmark and Egypt were comparable in terms of age and gender distribution. In Study I we found that significantly fewer individuals had experienced SP in Denmark [25 % (56/223)] than in Egypt [44 % (207/470)] p < .001. In Study II we found that individuals who had experienced at least one lifetime episode of SP from Denmark (n = 58) as compared to those from Egypt (n = 143) reported significantly fewer SP episodes in a lifetime relative to SP experiencers from Egypt (M = 6.0 vs. M = 19.4, p < .001). SP in the Egyptian sample was characterized by high rates of SP (as compared to in Denmark), frequent occurrences (three times that in the Denmark sample), prolonged immobility during SP, and great fear of dying from the experience. In addition, in Egypt, believing SP to be precipitated by the supernatural was associated with fear of the experience and longer SP immobility. Findings are discussed in the context of cultural elaboration and salience theories of SP. PMID:23884906

  10. Geospatial Modeling of Asthma Population in Relation to Air Pollution

    NASA Technical Reports Server (NTRS)

    Kethireddy, Swatantra R.; Tchounwou, Paul B.; Young, John H.; Luvall, Jeffrey C.; Alhamdan, Mohammad

    2013-01-01

    Current observations indicate that asthma is growing every year in the United States, specific reasons for this are not well understood. This study stems from an ongoing research effort to investigate the spatio-temporal behavior of asthma and its relatedness to air pollution. The association between environmental variables such as air quality and asthma related health issues over Mississippi State are investigated using Geographic Information Systems (GIS) tools and applications. Health data concerning asthma obtained from Mississippi State Department of Health (MSDH) for 9-year period of 2003-2011, and data of air pollutant concentrations (PM2.5) collected from USEPA web resources, and are analyzed geospatially to establish the impacts of air quality on human health specifically related to asthma. Disease mapping using geospatial techniques provides valuable insights into the spatial nature, variability, and association of asthma to air pollution. Asthma patient hospitalization data of Mississippi has been analyzed and mapped using quantitative Choropleth techniques in ArcGIS. Patients have been geocoded to their respective zip codes. Potential air pollutant sources of Interstate highways, Industries, and other land use data have been integrated in common geospatial platform to understand their adverse contribution on human health. Existing hospitals and emergency clinics are being injected into analysis to further understand their proximity and easy access to patient locations. At the current level of analysis and understanding, spatial distribution of Asthma is observed in the populations of Zip code regions in gulf coast, along the interstates of south, and in counties of Northeast Mississippi. It is also found that asthma is prevalent in most of the urban population. This GIS based project would be useful to make health risk assessment and provide information support to the administrators and decision makers for establishing satellite clinics in future.

  11. The associations of morningness-eveningness with anger and impulsivity in the general population.

    PubMed

    Hwang, Jeong Yeon; Kang, Seung-Gul; Gwak, Ah Reum; Park, Juhyun; Lee, Yu Jin

    2016-01-01

    The aim of this study was to investigate the relationships among morningness-eveningness, impulsivity and anger in the general population. A total of 1000 community-dwelling subjects (500 males) aged 20-77 years (mean± SD age: 39.6 ± 11.6 years) completed the morningness-eveningness questionnaire (MEQ), Barratt impulsiveness scale (BIS), Spielberger State-Trait Anger Expression Inventory (STAXI) and Center for Epidemiologic Studies Depression Scale. Moderation and mediation analyses were performed to determine whether the relationship between two variables depended on the third variable, referred to as a moderator, and whether the third variable, known as a mediator, was associated with the other two variables establishing causation. The MEQ scores exhibited significant negative associations with BIS (p < 0.001) and STAXI (p < 0.001) scores, and high scores on the BIS were associated with high scores on the STAXI (p < 0.001). Impulsivity, as measured by the BIS, played a role as a moderator (p < 0.001) in the relationship between MEQ and STAXI, and anger, as measured by the STAXI, acted as moderator (p = 0.030) in the association between MEQ and BIS. However, after controlling for the interaction of the BIS and MEQ, the MEQ scores did not significantly predict STAXI scores (p = 0.070). Additionally, the effect size of the mediating effect of the BIS scores on the relationship between the MEQ and STAXI (percent mediation: 53.2%) was larger than that of the STAXI scores on the association between the MEQ and BIS (percent mediation: 31.8%). The present results demonstrate that morningness-eveningness was closely related with both impulsivity and anger in the general population. Furthermore, these findings suggest that impulsivity may exercise a great influence on the association between morningness-eveningness and anger in two ways: as a moderator by modulating this relationship based on the level of impulsivity and as a mediator by acting as an intermediary factor.

  12. Accuracy of genomic prediction when combining two related crossbred populations.

    PubMed

    Vallée, A; van Arendonk, J A M; Bovenhuis, H

    2014-10-01

    Charolais bulls are selected for their crossbreed performance when mated to Montbéliard or Holstein dams. To implement genomic prediction, one could build a reference population for each crossbred population independently. An alternative could be to combine both crossbred populations into a single reference population to increase size and accuracy of prediction. The objective of this study was to investigate the accuracy of genomic prediction by combining different crossbred populations. Three scenarios were considered: 1) using 1 crossbred population as reference to predict phenotype of animals from the same crossbred population, 2) combining the 2 crossbred populations into 1 reference to predict phenotype of animals from 1 crossbred population, and 3) using 1 crossbred population as reference to predict phenotype of animals from the other crossbred population. Traits studied were bone thinness, height, and muscular development. Phenotypes and 45,117 SNP genotypes were available for 1,764 Montbéliard × Charolais calves and 447 Holstein × Charolais calves. The population was randomly spilt into 10 subgroups, which were assigned to the validation one by one. To allow fair comparison between scenarios, size of the reference population was kept constant for all scenarios. Breeding values were estimated with BLUP and genomic BLUP. Accuracy of prediction was calculated as the correlation between the EBV and the phenotypic values of the calves in the validation divided by the square root of the heritability. Genomic BLUP showed higher accuracies (between 0.281 and 0.473) than BLUP (between 0.197 and 0.452). Accuracies tended to be highest when prediction was within 1 crossbred population, intermediate when populations were combined into the reference population, and lowest when prediction was across populations. Decrease in accuracy from a prediction within 1 population to a prediction across populations was more pronounced for bone thinness (-27%) and height (-29

  13. Parathyroid hormone and risk of heart failure in the general population

    PubMed Central

    Meng, Fanbo; Wang, Wei; Ma, Jianghong; Lin, Baisong

    2016-01-01

    Abstract Inconsistent findings have been reported on the association between the parathyroid hormone (PTH) level and risk of heart failure. We aimed to systematically evaluate the association between circulating level of PTH and risk of heart failure in the general population by conducting a meta-analysis. We made a comprehensive literature search in PubMed, Embase, VIP, CNKI, and Wanfang databases published until January 2016. Only prospective observational studies reporting the association between circulating level of PTH and risk of heart failure in the general population were selected. Pooled adjusted hazard ratio (HR) and corresponding 95% confidence intervals (CIs) were calculated for the highest versus lowest PTH category. Six studies with 25,207 participants identified. Higher circulating level of PTH was associated with an increased risk of heart failure (HR: 1.38; 95% CI 1.09–1.74) in a random effect model. Subgroup analyses revealed that the risk of heart failure was more pronounced among men (HR: 1.75; 95% CI 1.38–2.22) than in both genders. However, the risk increment was not statistically significant (HR: 1.12; 95% CI 0.76–1.66) in the middle-aged population. Higher PTH level is independently associated with an exacerbated risk of heart failure in the general population. PMID:27749533

  14. Dietary factors and lung function in the general population: wine and resveratrol intake.

    PubMed

    Siedlinski, M; Boer, J M A; Smit, H A; Postma, D S; Boezen, H M

    2012-02-01

    Wine intake is associated with a better lung function in the general population, yet the source of this effect is unknown. Resveratrol, a polyphenol in wine, has anti-inflammatory properties in the lung, its effects being partially mediated via induction of Sirtuin (SIRT)1 activity. We assessed the impact of wine and resveratrol intake, and SIRT1 single-nucleotide polymorphisms (SNPs) on lung function in the general population. Effects of red and white wine and resveratrol intake on forced expiratory volume in 1 s (FEV(1)), forced vital capacity (FVC) and FEV(1)/FVC were analysed in the population-based Doetinchem cohort (n=3,224). Associations of four tagging SIRT1 SNPs with lung function were analysed in the Doetinchem (n=1,152) and Vlagtwedde-Vlaardingen (n=1,390) cohorts. Resveratrol intake was associated with higher FVC levels, and white wine intake with higher FEV(1) levels and lower risk of airway obstruction. SIRT1 SNPs were not significantly associated with level or course of lung function, either directly or indirectly via wine or resveratrol intake. This study shows a positive association of resveratrol intake with lung function in the general population, confirms the previously reported positive association of white wine intake with higher levels of FEV(1), and additionally shows an association with a higher FEV(1)/FVC ratio. These effects probably do not run via SNPs in SIRT1.

  15. A Time Domain Waveform for Testing General Relativity

    NASA Astrophysics Data System (ADS)

    Huwyler, Cédric; Porter, Edward K.; Jetzer, Philippe

    2015-05-01

    Gravitational-wave parameter estimation is only as good as the theory the waveform generation models are based upon. It is therefore crucial to test General Relativity (GR) once data becomes available. Many previous works, such as studies connected with the ppE framework by Yunes and Pretorius, rely on the stationary phase approximation (SPA) to model deviations from GR in the frequency domain. As Fast Fourier Transform algorithms have become considerably faster and in order to circumvent possible problems with the SPA, we test GR with corrected time domain waveforms instead of SPA waveforms. Since a considerable amount of work has been done already in the field using SPA waveforms, we establish a connection between leading-order-corrected waveforms in time and frequency domain, concentrating on phase-only corrected terms. In a Markov Chain Monte Carlo study, whose results are preliminary and will only be available later, we will assess the ability of the eLISA detector to measure deviations from GR for signals coming from supermassive black hole inspirals using these corrected waveforms.

  16. Cosmology in time asymmetric extensions of general relativity

    SciTech Connect

    Leon, Genly; Saridakis, Emmanuel N. E-mail: Emmanuel_Saridakis@baylor.edu

    2015-11-01

    We investigate the cosmological behavior in a universe governed by time asymmetric extensions of general relativity, which is a novel modified gravity based on the addition of new, time-asymmetric, terms on the Hamiltonian framework, in a way that the algebra of constraints and local physics remain unchanged. Nevertheless, at cosmological scales these new terms can have significant effects that can alter the universe evolution, both at early and late times, and the freedom in the choice of the involved modification function makes the scenario able to produce a huge class of cosmological behaviors. For basic ansatzes of modification, we perform a detailed dynamical analysis, extracting the stable late-time solutions. Amongst others, we find that the universe can result in dark-energy dominated, accelerating solutions, even in the absence of an explicit cosmological constant, in which the dark energy can be quintessence-like, phantom-like, or behave as an effective cosmological constant. Moreover, it can result to matter-domination, or to a Big Rip, or experience the sequence from matter to dark energy domination. Additionally, in the case of closed curvature, the universe may experience a cosmological bounce or turnaround, or even cyclic behavior. Finally, these scenarios can easily satisfy the observational and phenomenological requirements. Hence, time asymmetric cosmology can be a good candidate for the description of the universe.

  17. Scale-invariant alternatives to general relativity. II. Dilaton properties

    NASA Astrophysics Data System (ADS)

    Karananas, Georgios K.; Shaposhnikov, Mikhail

    2016-04-01

    In the present paper, we revisit gravitational theories which are invariant under TDiffs—transverse (volume-preserving) diffeomorphisms and global scale transformations. It is known that these theories can be rewritten in an equivalent diffeomorphism-invariant form with an action including an integration constant (cosmological constant for the particular case of non-scale-invariant unimodular gravity). The presence of this integration constant, in general, breaks explicitly scale invariance and induces a runaway potential for the (otherwise massless) dilaton, associated with the determinant of the metric tensor. We show, however, that if the metric carries mass dimension [GeV] -2 , the scale invariance of the system is preserved, unlike the situation in theories in which the metric has mass dimension different from -2 . The dilaton remains massless and couples to other fields only through derivatives, without any conflict with observations. We observe that one can define a specific limit for fields and their derivatives (in particular, the dilaton goes to zero, potentially related to the small distance domain of the theory) in which the only singular terms in the action correspond to the Higgs mass and the cosmological constant. We speculate that the self-consistency of the theory may require the regularity of the action, leading to the absence of the bare Higgs mass and cosmological constant, whereas their small finite values may be generated by nonperturbative effects.

  18. Bose gas with generalized dispersion relation plus an energy gap

    NASA Astrophysics Data System (ADS)

    Solis, M. A.; Martinez, J. G.; Garcia, J.

    We report the critical temperature, the condensed fraction, the internal energy and the specific heat for a d-dimensional Bose gas with a generalized dispersion relation plus an energy gap, i.e., ɛ =ɛ0 for k = 0 and ɛ =ɛ0 + Δ +csks , for k > 0 , where ℏk is the particle momentum, ɛ0 the lowest particle energy, cs a constant with dimension of energy multiplied by a length to the power s > 0 . When Δ > 0 , a Bose-Einstein critical temperature Tc ≠ 0 exists for any d / s >= 0 at which the internal energy shows a peak and the specific heat shows a jump. The critical temperature and the specific heat jump increase as functions of the gap but they decrease as functions of d / s . Thermodynamic properties are ɛ0 independent since this is just a reference energy. For Δ = 0 we recover the results reported in Ref. [1]. V. C. Aguilera-Navarro, M. de Llano y M. A. Solís, Eur. J. Phys. 20, 177 (1999). We acknowledge partial support from Grants PAPIIT IN111613 and CONACyT 221030.

  19. Cosmological constant implementing Mach principle in general relativity

    NASA Astrophysics Data System (ADS)

    Namavarian, Nadereh; Farhoudi, Mehrdad

    2016-10-01

    We consider the fact that noticing on the operational meaning of the physical concepts played an impetus role in the appearance of general relativity (GR). Thus, we have paid more attention to the operational definition of the gravitational coupling constant in this theory as a dimensional constant which is gained through an experiment. However, as all available experiments just provide the value of this constant locally, this coupling constant can operationally be meaningful only in a local area. Regarding this point, to obtain an extension of GR for the large scale, we replace it by a conformal invariant model and then, reduce this model to a theory for the cosmological scale via breaking down the conformal symmetry through singling out a specific conformal frame which is characterized by the large scale characteristics of the universe. Finally, we come to the same field equations that historically were proposed by Einstein for the cosmological scale (GR plus the cosmological constant) as the result of his endeavor for making GR consistent with the Mach principle. However, we declare that the obtained field equations in this alternative approach do not carry the problem of the field equations proposed by Einstein for being consistent with Mach's principle (i.e., the existence of de Sitter solution), and can also be considered compatible with this principle in the Sciama view.

  20. Cosmological applications of singular hypersurfaces in general relativity

    NASA Astrophysics Data System (ADS)

    Laguna-Castillo, Pablo

    Three applications to cosmology of surface layers, based on Israel's formalism of singular hypersurfaces and thin shells in general relativity, are presented. Einstein's field equations are analyzed in the presence of a bubble nucleated in vacuum phase transitions within the context of the old inflationary universe scenario. The evolution of a bubble with vanishing surface energy density is studied. It is found that such bubbles lead to a worm-hole matching. Next, the observable four-dimensional universe is considered as a singular hypersurface of discontinuity embedded in a five-dimensional Kaluza-Klein cosmology. It is possible to rewrite the projected five-dimensional Einstein equations on the surface layer in a similar way to the four-dimensional Robertson-Walker cosmology equations. Next, a model is described for an infinite-length, straight U(1) cosmic string as a cylindrical, singular shell enclosing a region of false vacuum. A set of equations is introduced which are required to develop a three-dimensional computer code whose purpose is to study the process of intercommuting cosmic strings with the inclusion of gravitational effects. The outcome is evolution and constraint equations for the gravitational, scalar and gauge field of two initially separated, perpendicular, cosmic strings.

  1. On tests of general relativity with binary radio pulsars

    NASA Astrophysics Data System (ADS)

    Del Pozzo, W.; Vecchio, A.

    2016-10-01

    The timing of radio pulsars in binary systems provides a superb testing ground of general relativity. Here we propose a Bayesian approach to carry out these tests, and a relevant efficient numerical implementation, that has several conceptual and practical advantages with respect to traditional methods based on least-squares fit that have been used so far: (i) it accounts for the actual structure of the likelihood function - and it is not predicated on the Laplace approximation which is implicitly built in least-squares fit that can potentially bias the inference - (ii) it provides the ratio of the evidences of any two models under consideration as the statistical quantity to compare different theories, and (iii) it allows us to put joint constraints from the monitoring of multiple systems, that can be expressed in terms of ratio of evidences or probability intervals of global (thus not system-dependent) parameters of the theory, if any exists. Our proposed approach optimally exploits the progress in timing of radio pulsars and the increase in the number of observed systems. We demonstrate the power of this framework using simulated data sets that are representative of current observations.

  2. Testing general relativity with present and future astrophysical observations

    NASA Astrophysics Data System (ADS)

    Berti, Emanuele; Barausse, Enrico; Cardoso, Vitor; Gualtieri, Leonardo; Pani, Paolo; Sperhake, Ulrich; Stein, Leo C.; Wex, Norbert; Yagi, Kent; Baker, Tessa; Burgess, C. P.; Coelho, Flávio S.; Doneva, Daniela; De Felice, Antonio; Ferreira, Pedro G.; Freire, Paulo C. C.; Healy, James; Herdeiro, Carlos; Horbatsch, Michael; Kleihaus, Burkhard; Klein, Antoine; Kokkotas, Kostas; Kunz, Jutta; Laguna, Pablo; Lang, Ryan N.; Li, Tjonnie G. F.; Littenberg, Tyson; Matas, Andrew; Mirshekari, Saeed; Okawa, Hirotada; Radu, Eugen; O'Shaughnessy, Richard; Sathyaprakash, Bangalore S.; Van Den Broeck, Chris; Winther, Hans A.; Witek, Helvi; Emad Aghili, Mir; Alsing, Justin; Bolen, Brett; Bombelli, Luca; Caudill, Sarah; Chen, Liang; Degollado, Juan Carlos; Fujita, Ryuichi; Gao, Caixia; Gerosa, Davide; Kamali, Saeed; Silva, Hector O.; Rosa, João G.; Sadeghian, Laleh; Sampaio, Marco; Sotani, Hajime; Zilhao, Miguel

    2015-12-01

    One century after its formulation, Einstein's general relativity (GR) has made remarkable predictions and turned out to be compatible with all experimental tests. Most of these tests probe the theory in the weak-field regime, and there are theoretical and experimental reasons to believe that GR should be modified when gravitational fields are strong and spacetime curvature is large. The best astrophysical laboratories to probe strong-field gravity are black holes and neutron stars, whether isolated or in binary systems. We review the motivations to consider extensions of GR. We present a (necessarily incomplete) catalog of modified theories of gravity for which strong-field predictions have been computed and contrasted to Einstein's theory, and we summarize our current understanding of the structure and dynamics of compact objects in these theories. We discuss current bounds on modified gravity from binary pulsar and cosmological observations, and we highlight the potential of future gravitational wave measurements to inform us on the behavior of gravity in the strong-field regime.

  3. Assessing the Representativeness of Population-Sampled Health Surveys Through Linkage to Administrative Data on Alcohol-Related Outcomes

    PubMed Central

    Gorman, Emma; Leyland, Alastair H.; McCartney, Gerry; White, Ian R.; Katikireddi, Srinivasa Vittal; Rutherford, Lisa; Graham, Lesley; Gray, Linsay

    2014-01-01

    Health surveys are an important resource for monitoring population health, but selective nonresponse may impede valid inference. This study aimed to assess nonresponse bias in a population-sampled health survey in Scotland, with a focus on alcohol-related outcomes. Nonresponse bias was assessed by examining whether rates of alcohol-related harm (i.e., hospitalization or death) and all-cause mortality among respondents to the Scottish Health Surveys (from 1995 to 2010) were equivalent to those in the general population, and whether the extent of any bias varied according to sociodemographic attributes or over time. Data from consenting respondents (aged 20–64 years) to 6 Scottish Health Surveys were confidentially linked to death and hospitalization records and compared with general population counterparts. Directly age-standardized incidence rates of alcohol-related harm and all-cause mortality were lower among Scottish Health Survey respondents compared with the general population. For all years combined, the survey-to-population rate ratios were 0.69 (95% confidence interval: 0.61, 0.76) for the incidence of alcohol-related harm and 0.89 (95% confidence interval: 0.83, 0.96) for all-cause mortality. Bias was more pronounced among persons residing in more deprived areas; limited evidence was found for regional or temporal variation. This suggests that corresponding underestimation of population rates of alcohol consumption is likely to be socially patterned. PMID:25227767

  4. Sleep Difficulties and Insomnia Symptoms in Norwegian Musicians Compared to the General Population and Workforce.

    PubMed

    Vaag, Jonas; Saksvik-Lehouillier, Ingvild; Bjørngaard, Johan Håkon; Bjerkeset, Ottar

    2016-01-01

    Sleep problems are reported as common among performing artists and musicians. However, epidemiological research comparing musicians to different groups of the general population is lacking. For this study, 4,168 members of the Norwegian Musician's Union were invited to an online survey regarding work and health. Of the 2,121 (51%) respondents, 1,607 were active performing musicians. We measured prevalence of insomnia symptoms using the Bergen Insomnia Scale (BIS), and compared this sample to a representative sample of the general Norwegian population (n = 2,645). Overall, musicians had higher prevalence of insomnia symptoms compared to the general population (Prevalence Difference 6.9, 95% Confidence Interval 3.9-10.0). Item response analysis showed that this difference was mainly explained by nonrestorative sleep and dissatisfaction with sleep among musicians. An additional analysis, comparing musicians to the general Norwegian workforce (n = 8,518) on sleep difficulties, confirmed this tendency (Prevalence Difference 6.2, 95% Confidence Interval 4.3-8.1). Musicians performing classical, contemporary, rock, and country music reported the highest prevalence of insomnia, and these genres might be of special interest when developing preventative measures, treatment strategies, and further research on sleep difficulties among musicians.

  5. Mortality Among Adults With Intellectual Disability in England: Comparisons With the General Population

    PubMed Central

    Hosking, Fay J.; Shah, Sunil M.; Harris, Tess; DeWilde, Stephen; Beighton, Carole; Cook, Derek G.

    2016-01-01

    Objectives. To describe mortality among adults with intellectual disability in England in comparison with the general population. Methods. We conducted a cohort study from 2009 to 2013 using data from 343 general practices. Adults with intellectual disability (n = 16 666; 656 deaths) were compared with age-, gender-, and practice-matched controls (n = 113 562; 1358 deaths). Results. Adults with intellectual disability had higher mortality rates than controls (hazard ratio [HR] = 3.6; 95% confidence interval [CI] = 3.3, 3.9). This risk remained high after adjustment for comorbidity, smoking, and deprivation (HR = 3.1; 95% CI = 2.7, 3.4); it was even higher among adults with intellectual disability and Down syndrome or epilepsy. A total of 37.0% of all deaths among adults with intellectual disability were classified as being amenable to health care intervention, compared with 22.5% in the general population (HR = 5.9; 95% CI = 5.1, 6.8). Conclusions. Mortality among adults with intellectual disability is markedly elevated in comparison with the general population, with more than a third of deaths potentially amenable to health care interventions. This mortality disparity suggests the need to improve access to, and quality of, health care among people with intellectual disability. PMID:27310347

  6. GENERAL: A Possible Population-Driven Phase Transition in Cicada Chorus

    NASA Astrophysics Data System (ADS)

    Gu, Si-Yuan; Jin, Yu-Liang; Zhao, Xiao-Xue; Huang, Ji-Ping

    2009-06-01

    We investigate the collective synchronization of cicada chirping. Using both experimental and phenomenological numerical techniques, here we show that the onset of a periodic two-state acoustic synchronous behavior in cicada chorus depends on a critical size of population Nc = 21, above which a typical chorus state appears periodically with a 30 second-silence state in between, and further clarify its possibility concerning a new class of phase transition, which is unusually driven by population. This work has relevance to acoustic synchronization and to general physics of phase transition.

  7. Fluctuation Relations of Fitness and Information in Population Dynamics

    NASA Astrophysics Data System (ADS)

    Kobayashi, Tetsuya J.; Sughiyama, Yuki

    2015-12-01

    Phenotype switching with and without sensing environment is a common strategy of organisms to survive in a fluctuating environment. Understanding the evolutionary advantages of switching and sensing requires a quantitative evaluation of their fitness gain and its fluctuation together with the conditions for the switching and sensing strategies being adapted to a given environment. In this work, by using a pathwise formulation of the population dynamics, we show that the optimal switching strategy is characterized by a consistency condition for time-forward and backward path probabilities. The formulation also clarifies the underlying information-theoretic aspect of selection as a passive information compression. The loss of fitness by a suboptimal strategy is also shown to satisfy a fluctuation relation, which provides us with the information on how environmental fluctuation impacts the advantages of the optimal strategy. These results are naturally extended to the situation that organisms can use an environmental signal by actively sensing the environment. The fluctuation relations of the fitness gain by sensing are derived in which the multivariate mutual information among the phenotype, the environment, and the signal plays the role to quantify the relevant information in the signal for the fitness gain.

  8. How absorption selected galaxies trace the general high-redshift galaxy population

    NASA Astrophysics Data System (ADS)

    Christensen, Lise

    2015-08-01

    Strong absorption lines seen in quasar spectra arise when the lines of sight to the quasars intersect intervening galaxies. The associated metal absorption lines from the strongest absorption lines, the damped Lyman alpha absorbers (DLAs), allow us to trace the metallicity of galaxies back to redshifts z>5. Typical metallicities range from 0.1-100% solar metallicities with a huge scatter at any given redshift. Understanding the nature of galaxies that host DLAs is one strategy to probe the early phase and origin of stars in the outskirts of present-day galaxy disks.The search for emission from the elusive high-redshift DLA galaxies has reached a mature state now that we have determined how to best identify the absorbing galaxies. From a growing number of emission-line detections from DLA galaxies at redshifts ranging between 0.1 and 3, we can analyse galaxies in both absorption and emission, and probe the gas-phase metallicities in the outskirts and halos of the galaxies.By combining information for galaxies seen in emission and absorption, I will show that there is a relation between DLA metallicities and the host galaxy luminosities similar to the well-known the mass-metallicity relation for luminosity selected galaxies. This implies that DLA galaxies are drawn from the general population of low- to intermediate mass galaxies. We can determine a metallicity gradient in the extended halo of the galaxies out to ~40 kpc, and this allows us to reproduce observed galaxy correlation functions derived from conventional samples of luminosity selected galaxies.

  9. The Association between Dietary Patterns and Semen Quality in a General Asian Population of 7282 Males

    PubMed Central

    Liu, Chin-Yu; Chou, Yu-Ching; Chao, Jane C. -J.; Hsu, Chien-Yeh; Cha, Tai-Lung; Tsao, Chih-Wei

    2015-01-01

    Objective To explore the associations between different dietary patterns and semen quality in a general Asian male population. Methods Cross-sectional study. Healthy Taiwanese men aged 18 years or older who participated in a standard medical screening program from 2008-2013 run by a private firm were included in this study. Semen parameters including sperm concentration (SC), total sperm motility (TSM), progressive motility (PRM) and normal sperm morphology (NSM) were recorded. A dietary questionnaire was used to categorize the participants into 5 groups: “Healthy diet”, “Western diet”, “High-carbohydrate diet”, “High sweet snacks & sugar-sweetened drinks” and “High-sodium diet”. Results A total of 7282 men completed the questionnaire regarding dietary pattern, and examination of anthropometric indexes was performed and laboratory data were obtained. A high intake of a “Western diet” resulted in statistically linear declines of SC and NSM (P < 0.001 and P < 0.001). Similarly, a greater intake of “High sweet snacks & sugar-sweetened drinks” was associated with a lower SC (P = 0.001). Increased intake of a “High-carbohydrate diet” was related to higher prevalences of abnormal TSM and PRM (P = 0.012 and P = 0.025). Similarly, a greater intake of a “High-sodium diet” was correlated with an elevated prevalence of abnormal NSM (P = 0.035). Conclusions This study showed that a greater intake of a “Western diet” is associated with poorer SC and NSM, a “High sweet snacks and sugar-sweetened drinks” intake is correlated with a lower SC, and high-carbohydrate food is related to elevated prevalences of abnormal TSM and PRM. PMID:26218796

  10. Assessing sub-clinical psychosis phenotypes in the general population--a multidimensional approach.

    PubMed

    Rössler, Wulf; Ajdacic-Gross, Vladeta; Müller, Mario; Rodgers, Stephanie; Haker, Helene; Hengartner, Michael P

    2015-02-01

    Several studies have demonstrated that expression of a psychosis phenotype can be observed below the threshold of its clinical detection. To date, however, no conceptual certainty has been reported for the validity and reliability of sub-clinical psychosis. Our main objectives were to assess the prevalence rates and severity of various psychosis symptoms in a representative community sample. Furthermore, we wanted to analyze which latent factors are depicted by several currently used psychosis questionnaires. We also examined how those latent factors for sub-clinical psychosis are linked to psychosocial factors, normal personality traits, and coping abilities related to chronic stress. Most of the eight subscales from the Paranoia Checklist and the Structured Interview for Assessing Perceptual Anomalies had a very similar type of distribution, i.e., an inverse Gaussian (Wald) distribution. This supported the notion of a continuity of psychotic symptoms, which we would expect to find for continuously distributed symptoms within the general population. Sub-clinical psychosis can be reduced to two different factors - one representing odd beliefs about the world and odd behavior, and the other one representing anomalous perceptions (such as hallucinations). Persons with odd beliefs and behavior are under greater burden and more susceptible to psychosocial risks than are persons with anomalous perceptions. These sub-clinical psychosis syndromes are also related to stable personality traits. In conclusion, we obtained strong support for the notion that there is no natural cut-off separating psychotic illness from good health. Sub-clinical psychosis of any kind is not trivial because it is associated with various types of social disability. PMID:25523751

  11. Failure to thrive: the prevalence and concurrence of anthropometric criteria in a general infant population

    PubMed Central

    Olsen, E M; Petersen, J; Skovgaard, A M; Weile, B; Jørgensen, T; Wright, C M

    2007-01-01

    Background Failure to thrive (FTT) in early childhood is associated with subsequent developmental delay and is recognised to reflect relative undernutrition. Although the concept of FTT is widely used, no consensus exists regarding a specific definition, and it is unclear to what extent different anthropometric definitions concur. Objective To compare the prevalence and concurrence of different anthropometric criteria for FTT and test the sensitivity and positive predictive values of these in detecting children with “significant undernutrition”, defined as the combination of slow conditional weight gain and low body mass index (BMI). Methods Seven criteria of FTT, including low weight for age, low BMI, low conditional weight gain and Waterlow's criterion for wasting, were applied to a birth cohort of 6090 Danish infants. The criteria were compared in two age groups: 2–6 and 6–11 months of life. Results 27% of infants met one or more criteria in at least one of the two age groups. The concurrence among the criteria was generally poor, with most children identified by only one criterion. Positive predictive values of different criteria ranged from 1% to 58%. Most single criteria identified either less than half the cases of significant undernutrition (found in 3%) or included far too many, thus having a low positive predictive value. Children with low weight for height tended to be relatively tall. Conclusions No single measurement on its own seems to be adequate for identifying nutritional growth delay. Further longitudinal population studies are needed to investigate the discriminating power of different criteria in detecting significant undernutrition and subsequent outcomes. PMID:16531456

  12. Explaining the disability paradox: a cross-sectional analysis of the Swiss general population

    PubMed Central

    2012-01-01

    Background Disability can be broken down into difficulties in different components of functioning such as impairments and limitations in activities and participation (A&P). Previous studies have produced the seemingly surprising result that persons with severe impairments tend to report high quality of life (QoL) including perceived health regardless of their condition; the so-called “disability paradox”. We aim to study the role of contextual factors (i.e. the personal and environmental situation) in explaining the disability paradox. Methods The Swiss Health Survey provides information on the perceived health of 18,760 participants from the general population. We construct a conditional independence graph applying random forests and stability selection in order to represent the structure of impairment, A&P limitation, contextual factors, and perceived health. Results We find that impairment and A&P limitations are not directly related but only via a cluster of contextual factors. Similarly, impairment and perceived health are not directly related. On the other hand, perceived health is directly connected with A&P limitations. We hypothesize that contextual factors have a moderating and/or mediating effect on the relationship of impairment, A&P limitations, and perceived health. Conclusion The disability paradox seems to dissolve when contextual factors are put into consideration. Contextual factors may be responsible for some persons with impairments developing A&P limitations and others not. In turn, persons with impairments may only then perceive bad health when they experience A&P limitation. Political interventions at the level of the environment may reduce the number of persons who perceive bad health. PMID:22894722

  13. Use of generalized population ratios to obtain Fe XV line intensities and linewidths at high electron densities

    NASA Technical Reports Server (NTRS)

    Kastner, S. O.; Bhatia, A. K.

    1980-01-01

    A generalized method for obtaining individual level population ratios is used to obtain relative intensities of extreme ultraviolet Fe XV emission lines in the range 284-500 A, which are density dependent for electron densities in the tokamak regime or higher. Four lines in particular are found to attain quite high intensities in the high-density limit. The same calculation provides inelastic contributions to linewidths. The method connects level populations and level widths through total probabilities t(ij), related to 'taboo' probabilities of Markov chain theory. The t(ij) are here evaluated for a real atomic system, being therefore of potential interest to random-walk theorists who have been limited to idealized systems characterized by simplified transition schemes.

  14. Probing General Relativity and New Physics with Lunar Laser Ranging

    NASA Astrophysics Data System (ADS)

    Dell'Agnello, S.; Maiello, M.; Currie, D. G.; Boni, A.; Berardi, S.; Cantone, C.; Delle Monache, G. O.; Intaglietta, N.; Lops, C.; Garattini, M.; Martini, M.; Patrizi, G.; Porcelli, L.; Tibuzzi, M.; Vittori, R.; Bianco, G.; Coradini, A.; Dionisio, C.; March, R.; Bellettini, G.; Tauraso, R.; Chandler, J.

    2012-11-01

    Over the past 40 years, Lunar Laser Ranging (LLR, developed by the Univ. of Maryland (PI) and INFN-LNF (Co-PI)) to the Apollo Cube Corner Retroreflector (CCR) arrays have supplied almost all the significant tests of General Relativity (Currie et al., 2009 [12]). LLR can evaluate the PPN (Post Newtonian Parameters), addressing this way both the possible changes in the gravitational constant and the self-energy properties of the gravitational field. In addition, the LLR has provided significant information on the composition and origin of the Moon. This is the only Apollo experiment that is still in operation. Initially the Apollo LLR arrays contributed a negligible fraction of the ranging error budget. Over the decades, the ranging capabilities of the ground stations have improved by more than two orders of magnitude. Now, because of the lunar librations, the existing Apollo retroreflector arrays contribute a significant fraction of the limiting errors in the range measurements. We built a new experimental apparatus (the ‘Satellite/Lunar Laser Ranging Characterization Facility', SCF) and created a new test procedure (the SCF-Test) to characterize and model the detailed thermal behavior and the optical performance of cube corner laser retroreflectors in space for industrial and scientific applications (Dell'Agnello et al., 2011 [13]). Our key experimental innovation is the concurrent measurement and modeling of the optical Far Field Diffraction Pattern (FFDP) and the temperature distribution of the SLR retroreflector payload under thermal conditions produced with a close-match solar simulator. The apparatus includes infrared cameras for non-invasive thermometry, thermal control and real-time movement of the payload to experimentally simulate satellite orientation on orbit with respect to both solar illumination and laser interrogation beams. These unique capabilities provide experimental validation of the space segment for SLR and Lunar Laser Ranging (LLR). The

  15. The disruptive effects of pain on n-back task performance in a large general population sample.

    PubMed

    Attridge, Nina; Noonan, Donna; Eccleston, Christopher; Keogh, Edmund

    2015-10-01

    Pain captures attention, displaces current concerns, and prioritises escape and repair. This attentional capture can be measured by its effects on general cognition. Studies on induced pain, naturally occurring acute pain, and chronic pain all demonstrate a detrimental effect on specific tasks of attention, especially those that involve working memory. However, studies to date have relied on relatively small samples and/or one type of pain, thus restricting our ability to generalise to wider populations. We investigated the effect of pain on an n-back task in a large heterogeneous sample of 1318 adults. Participants were recruited from the general population and tested through the internet. Despite the heterogeneity of pain conditions, participant characteristics, and testing environments, we found a performance decrement on the n-back task for those with pain, compared with those without pain; there were significantly more false alarms on nontarget trials. Furthermore, we also found an effect of pain intensity; performance was poorer in participants with higher intensity compared with that in those with lower intensity pain. We suggest that the effects of pain on attention found in the laboratory occur in more naturalistic settings. Pain is common in the general population, and such interruption may have important, as yet uninvestigated, consequences for tasks of everyday cognition that involve working memory, such as concentration, reasoning, motor planning, and prospective memory.

  16. A Sex-Specific Comparison of Major Depressive Disorder Symptomatology in the Canadian Forces and the General Population

    PubMed Central

    Erickson, Julie; Kinley, D Jolene; Bolton, James M; Zamorski, Mark A; Enns, Murray W; Sareen, Jitender

    2014-01-01

    Objective: To compare major depressive disorder (MDD) symptomatology within men and women in a large, representative sample of Canadian military personnel and civilians. Method: We used the Canadian Community Health Survey: Mental Health and Well-Being (Cycle 1.2 and Canadian Forces Supplement) (n = 36 984 and n = 8441, respectively) to compare past-year MDD symptomatology among military and civilian women, and military and civilian men. Logistic regression models were used to determine differences in the types of depressive symptoms endorsed in each group. Results: Men in the military with MDD were at lower odds than men in the general population to endorse numerous symptoms of depression, such as hopelessness (adjusted odds ratio [AOR] 0.44; 99% CI 0.23 to 0.83) and inability to cope (AOR 0.53; 99% CI 0.31 to 0.92). Military women with MDD were at lower odds of thinking about their death (AOR 0.52; 99% CI 0.32 to 0.86), relative to women with MDD in the general population. Conclusion: Different MDD symptomatology among males and females in the military, compared with those in the general population, may reflect selection effects (for example, personality characteristics and patterns of comorbidity) or occupational experiences unique to military personnel. Future research examining the mechanisms behind MDD symptomatology in military personnel and civilians is required. PMID:25007423

  17. Probing modifications of general relativity using current cosmological observations

    SciTech Connect

    Zhao Gongbo; Bacon, David J.; Koyama, Kazuya; Nichol, Robert C.; Song, Yong-Seon; Giannantonio, Tommaso; Pogosian, Levon; Silvestri, Alessandra

    2010-05-15

    We test general relativity (GR) using current cosmological data: the CMB from WMAP5 [E. Komatsu et al. (WMAP Collaboration), Astrophys. J. Suppl. Ser. 180, 330 (2009)], the integrated Sachs-Wolfe (ISW) effect from the cross correlation of the CMB with six galaxy catalogs [T. Giannantonio et al., Phys. Rev. D 77, 123520 (2008)], a compilation of supernovae (SNe) type Ia including the latest Sloan Digital Sky Survey SNe [R. Kessler et al., Astrophys. J. Suppl. Ser. 185, 32 (2009).], and part of the weak lensing (WL) data from the Canada-Franco-Hawaii Telescope Legacy Survey [L. Fu et al., Astron. Astrophys. 479, 9 (2008); M. Kilbinger et al., Astron. Astrophys. 497, 677 (2009).] that probe linear and mildly nonlinear scales. We first test a model in which the effective Newtonian constant {mu} and the ratio of the two gravitational potentials, {eta}, transit from the GR value to another constant at late times; in this case, we find that GR is fully consistent with the combined data. The strongest constraint comes from the ISW effect which would arise from this gravitational transition; the observed ISW signal imposes a tight constraint on a combination of {mu} and {eta} that characterizes the lensing potential. Next, we consider four pixels in time and space for each function {mu} and {eta}, and perform a principal component analysis, finding that seven of the resulting eight eigenmodes are consistent with GR within the errors. Only one eigenmode shows a 2{sigma} deviation from the GR prediction, which is likely to be due to a systematic effect. However, the detection of such a deviation demonstrates the power of our time- and scale-dependent principal component analysis methodology when combining observations of structure formation and expansion history to test GR.

  18. Disseminating General Relativity for 21st century astronomy

    NASA Astrophysics Data System (ADS)

    Crosta, Mariateresa

    2015-08-01

    The talk aims to present two outreach projects - initially developed for the ESA Gaia satellite, a multidisciplinary mission launched on December 19, 2013 - available to the OAD community: NeST and "The Meaning of Light".NeST is an interactive educational tool, that displays how the theory of GR rules the Universe, it creates a performance physically "belonging" to the exhibition space and moving through it, materializing what J.A. Wheeler said "mass tells space-time how to curve, and space-time tells mass how to move"."The Meaning of Light" is a short motion comics, part of an extensive outreach program called "The History of Photons" whose main theme is the story of a beam of stellar photons that, after leaving the progenitor star, propagates through the Universe and, once intercepted come into contact with a team of scientists: here begins their adventure to be taken "back" home and in doing so the scientists, and the spectators, are driven to discover the wonders of which the light are the bearers.The description of the journey of the photons becomes, therefore, an opportunity to easily tell the fascinating topics of Astrophysics and General Relativity, i.e. the complexity and the infinite beauty of the Universe in which we live.For this movie a new theme song was produced, "Singing the Stars", whose refrain (Oh Be A Fine Girl / Guy Kiss Me Little Thing, Yeah) adds to the famous mnemonic for stellar classification (OBAFGKM) the new stellar types LTY discovered in recent years.

  19. A generalized Brownian motion model for turbulent relative particle dispersion

    NASA Astrophysics Data System (ADS)

    Shivamoggi, B. K.

    2016-08-01

    There is speculation that the difficulty in obtaining an extended range with Richardson-Obukhov scaling in both laboratory experiments and numerical simulations is due to the finiteness of the flow Reynolds number Re in these situations. In this paper, a generalized Brownian motion model has been applied to describe the relative particle dispersion problem in more realistic turbulent flows and to shed some light on this issue. The fluctuating pressure forces acting on a fluid particle are taken to be a colored noise and follow a stationary process and are described by the Uhlenbeck-Ornstein model while it appears plausible to take their correlation time to have a power-law dependence on Re, thus introducing a bridge between the Lagrangian quantities and the Eulerian parameters for this problem. This ansatz is in qualitative agreement with the possibility of a connection speculated earlier by Corrsin [26] between the white-noise representation for the fluctuating pressure forces and the large-Re assumption in the Kolmogorov [4] theory for the 3D fully developed turbulence (FDT) as well as a similar argument of Monin and Yaglom [23] and a similar result of Sawford [13] and Borgas and Sawford [24]. It also provides an insight into the result that the Richardson-Obukhov scaling holds only in the infinite-Re limit and disappears otherwise. This ansatz further provides a determination of the Richardson-Obukhov constant g as a function of Re, with an asymptotic constant value in the infinite-Re limit. It is shown to lead to full agreement, in the small-Re limit as well, with the Batchelor-Townsend [27] scaling for the rate of change of the mean square interparticle separation in 3D FDT, hence validating its soundness further.

  20. The spectrum of the liver disease in the general population: lesson from the Dionysos Study.

    PubMed

    Tiribelli, Claudio

    2002-01-01

    Differently for what happened for the heart and the cardiovascular diseases, no data were available on the prevalence of the liver disorders in the general population. Based on these considerations we started planning a cohort study aimed to obtain data on how frequent liver disease was in the general population. Two comparable town in Northern Italy (Campogalliano, Modena, and Cormons, Gorizia) were selected on the basis of number of inhabitants, census and socio-economic background, and 6.917 were screened with an overall compliance of 70%, a percentage adequate to validate this type of study. In each patient a semi-quantitative, color-illustrated, food questionnaire including detailed questions on the use of alcoholic beverages was obtained in addition to a detailed physical examination to detect liver and the biliary diseases. Blood sample for ALT, AST, GGT, MCV and platelet count, and HBV and HCV markers were also taken.

  1. Negative relationships between population density and metabolic rates are not general.

    PubMed

    Yashchenko, Varvara; Fossen, Erlend Ignacio; Kielland, Øystein Nordeide; Einum, Sigurd

    2016-07-01

    Population density has recently been suggested to be an important factor influencing metabolic rates and to represent an important 'third axis' explaining variation beyond that explained by body mass and temperature. In situations where population density influences food consumption, the immediate effect on metabolism acting through specific dynamic action (SDA), and downregulation due to fasting over longer periods, is well understood. However, according to a recent review, previous studies suggest a more general effect of population density per se, even in the absence of such effects. It has been hypothesized that this results from animals performing anticipatory responses (i.e. reduced activity) to expected declines in food availability. Here, we test the generality of this finding by measuring density effects on metabolic rates in 10 clones from two different species of the zooplankton Daphnia (Daphnia pulex Leydig and D. magna Straus). Using fluorescence-based respirometry, we obtain high-precision measures of metabolism. We also identify additional studies on this topic that were not included in the previous review, compare the results and evaluate the potential for measurement bias in all previous studies. We demonstrate significant variation in mass-specific metabolism among clones within both species. However, we find no evidence for a negative relationship between population density and mass-specific metabolism. The previously reported pattern also disappeared when we extended the set of studies analysed. We discuss potential reasons for the discrepancy among studies, including two main sources of potential bias (microbial respiration and declining oxygen consumption due to reduced oxygen availability). Only one of the previous studies gives sufficient information to conclude the absence of such biases, and consistent with our results, no effect of density on metabolism was found. We conclude that population density per se does not have a general effect

  2. Monitoring concentrations of persistent organic pollutants in the general population: the international experience.

    PubMed

    Porta, Miquel; Puigdomènech, Elisa; Ballester, Ferran; Selva, Javier; Ribas-Fitó, Núria; Llop, Sabrina; López, Tomàs

    2008-05-01

    Assessing the adverse effects on human health of persistent organic pollutants (POPs) and the impact of policies aiming to reduce human exposure to POPs warrants monitoring body concentrations of POPs in representative samples of subjects. While numerous ad hoc studies are being conducted to understand POPs effects, only a few countries are conducting nationwide surveillance programs of human concentrations of POPs, and even less countries do so in representative samples of the general population. We tried to identify all studies worldwide that analyzed the distribution of concentrations of POPs in a representative sample of the general population, and we synthesized the studies' main characteristics, as design, population, and chemicals analyzed. The most comprehensive studies are the National Reports on Human Exposure to Environmental Chemicals (USA), the German Environmental Survey, and the Arctic Monitoring and Assessment Programme. Population-wide studies exist as well in New Zealand, Australia, Japan, Flanders (Belgium) and the Canary Islands (Spain). Most such studies are linked with health surveys, which is a highly-relevant additional strength. Only the German and Flemish studies analyzed POPs by educational level, while studies in the USA offer results by ethnic group. The full distribution of POPs concentrations is unknown in many countries. Knowledge gaps include also the interplay of age, gender, period and cohort effects on the prevalence of exposures observed by cross-sectional surveys. Local and global efforts to minimize POPs contamination, like the Stockholm convention, warrant nationwide monitoring of concentrations of POPs in representative samples of the general population. Results of this review show how such studies may be developed and used. PMID:18054079

  3. An Economic Analysis of Cell-Free DNA Non-Invasive Prenatal Testing in the US General Pregnancy Population

    PubMed Central

    Benn, Peter; Curnow, Kirsten J.; Chapman, Steven; Michalopoulos, Steven N.; Hornberger, John; Rabinowitz, Matthew

    2015-01-01

    Objective Analyze the economic value of replacing conventional fetal aneuploidy screening approaches with non-invasive prenatal testing (NIPT) in the general pregnancy population. Methods Using decision-analysis modeling, we compared conventional screening to NIPT with cell-free DNA (cfDNA) analysis in the annual US pregnancy population. Sensitivity and specificity for fetal aneuploidies, trisomy 21, trisomy 18, trisomy 13, and monosomy X, were estimated using published data and modeling of both first- and second trimester screening. Costs were assigned for each prenatal test component and for an affected birth. The overall cost to the healthcare system considered screening costs, the number of aneuploid cases detected, invasive procedures performed, procedure-related euploid losses, and affected pregnancies averted. Sensitivity analyses evaluated the effect of variation in parameters. Costs were reported in 2014 US Dollars. Results Replacing conventional screening with NIPT would reduce healthcare costs if it can be provided for $744 or less in the general pregnancy population. The most influential variables were timing of screening entry, screening costs, and pregnancy termination rates. Of the 13,176 affected pregnancies undergoing screening, NIPT detected 96.5% (12,717/13,176) of cases, compared with 85.9% (11,314/13,176) by conventional approaches. NIPT reduced invasive procedures by 60.0%, with NIPT and conventional methods resulting in 24,596 and 61,430 invasive procedures, respectively. The number of procedure-related euploid fetal losses was reduced by 73.5% (194/264) in the general screening population. Conclusion Based on our analysis, universal application of NIPT would increase fetal aneuploidy detection rates and can be economically justified. Offering this testing to all pregnant women is associated with substantial prenatal healthcare benefits. PMID:26158465

  4. Influenza Hospitalizations Among American Indian/Alaska Native People and in the United States General Population

    PubMed Central

    Gounder, Prabhu P.; Callinan, Laura S.; Holman, Robert C.; Cheng, Po-Yung; Bruce, Michael G.; Redd, John T.; Steiner, Claudia A.; Bresee, Joseph; Hennessy, Thomas W.

    2014-01-01

    Background.  Historically, American Indian/Alaska Native (AI/AN) people have experienced a disproportionate burden of infectious disease morbidity compared with the general US population. We evaluated whether a disparity in influenza hospitalizations exists between AI/AN people and the general US population. Methods.  We used Indian Health Service hospital discharge data (2001–2011) for AI/AN people and 13 State Inpatient Databases (2001–2008) to provide a comparison to the US population. Hospitalization rates were calculated by respiratory year (July–June). Influenza-specific hospitalizations were defined as discharges with any influenza diagnoses. Influenza-associated hospitalizations were calculated using negative binomial regression models that incorporated hospitalization and influenza laboratory surveillance data. Results.  The mean influenza-specific hospitalization rate/100 000 persons/year during the 2001–2002 to 2007–2008 respiratory years was 18.6 for AI/AN people and 15.6 for the comparison US population. The age-adjusted influenza-associated hospitalization rate for AI/AN people (98.2; 95% confidence interval [CI], 51.6–317.8) was similar to the comparison US population (58.2; CI, 34.7–172.2). By age, influenza-associated hospitalization rates were significantly higher among AI/AN infants (<1 year) (1070.7; CI, 640.7–2969.5) than the comparison US infant population (210.2; CI, 153.5–478.5). Conclusions.  American Indian/Alaska Native people had higher influenza-specific hospitalization rates than the comparison US population; a significant influenza-associated hospitalization rate disparity was detected only among AI/AN infants because of the wide CIs inherent to the model. Taken together, the influenza-specific and influenza-associated hospitalization rates suggest that AI/AN people might suffer disproportionately from influenza illness compared with the general US population. PMID:25734102

  5. Usage patterns of aromatherapy among the French general population: A descriptive study focusing on dermal exposure.

    PubMed

    Dornic, N; Ficheux, A S; Roudot, A C; Saboureau, D; Ezzedine, K

    2016-04-01

    Although likely benefits of aromatherapy are well documented, little is known about essential oils consumption and exposure to molecules present in the oils. The aim of our study was to determine usage patterns of 12 types of essential oils among a quite large panel, sorted per sex and quintile of age from birth to 70. A survey was conducted in September 2014 among 1507 French individuals, selected to build a representative panel of the general population. The key point of our study, apart from the fact that it has never been done among general population, was the focus on dermal exposure. Information about types of essential oils used, skin areas exposed, frequencies and quantities were collected. Our work revealed that some sub-populations could be significantly exposed to molecules of toxicological concern, especially in terms of skin sensitization. This work is the first step to assess human exposure to these molecules, and will help safety authorities and risk managers to protect the population. PMID:26826550

  6. Awareness to sun exposure and use of sunscreen by the general population.

    PubMed

    Al Robaee, Ahmad A

    2010-11-01

    Sun exposure has a pathogenic effect on the development of skin cancer, whose prevalence increases worldwide. Educational programs are carried out to change high risk sun exposure behaviours. The aim of this study was to evaluate the knowledge of Saudi population regarding sun exposure and the risk of skin cancers, as well as to study their sun-protective attitudes and practices. A cross-sectional population-based survey using specially devised questionnaire on a stratified random sample of general population in Qassim Province between January and March 2010. One thousand three hundred and seventy six persons participated in the study. A high sun exposure of more than 10 hours per week was reported by 661 persons (48%). Fifty six percent of respondents were aware of the association between sun exposure and skin cancer but the rate of sun screen use was only 8.3%. Socio-demographic factors more likely to be associated with sunscreen use were: females, higher social class, higher levels of education, type 4 skin and married individuals. This study has indicated a low rate of sunscreen use by our population despite reasonably good knowledge about the hazards of sun exposure. This necessitates the need for health education program. We hope that the results of our study will be used for setting up a sun policy for Saudi general public.

  7. Frequency of dissociative identity disorder in the general population in Turkey.

    PubMed

    Akyüz, G; Doğan, O; Sar, V; Yargiç, L I; Tutkun, H

    1999-01-01

    This study attempted to determine the prevalence of dissociative identity disorder in the general population. The Dissociative Experiences Scale (DES) was administered to 994 subjects in 500 homes who constituted a representative sample of the population of Sivas City, Turkey. The mean DES score was 6.7+/-6.1 (mean +/- SD). Of the 62 respondents who scored above 17 on the DES, 32 (51.6%) could be contacted during the second phase of the study. They were matched for age and gender with a group of respondents who scored below 10 on the scale, and the Dissociative Disorders Interview Schedule (DDIS) was then administered to both groups. Seventeen subjects (1.7%) received a diagnosis of dissociative disorder according to the structured interview. In the third phase, eight of 17 subjects who had a dissociative disorder on the structured interview could be contacted for a clinical evaluation. They were matched with a nondissociative control group and interviewed by a clinician blind to the structured interview diagnosis. Four of eight subjects were diagnosed clinically with dissociative identity disorder, yielding a minimum prevalence of 0.4%. Dissociative identity disorder is not rare in the general population. Self-rating instruments and structured interviews can be used successfully for screening these cases. Our data, derived from a population with no public awareness about dissociative identity disorder and no exposure to systematic psychotherapy, suggest that dissociative identity disorder cannot be considered simply an iatrogenic artifact, a culture-bound syndrome, or a phenomenon induced by media influences.

  8. The relation between multilocus population genetics and social evolution theory.

    PubMed

    Gardner, Andy; West, Stuart A; Barton, Nicholas H

    2007-02-01

    Evolution at multiple gene positions is complicated. Direct selection on one gene disturbs the evolutionary dynamics of associated genes. Recent years have seen the development of a multilocus methodology for modeling evolution at arbitrary numbers of gene positions with arbitrary dominance and epistatic relations, mode of inheritance, genetic linkage, and recombination. We show that the approach is conceptually analogous to social evolutionary methodology, which focuses on selection acting on associated individuals. In doing so, we (1) make explicit the links between the multilocus methodology and the foundations of social evolution theory, namely, Price's theorem and Hamilton's rule; (2) relate the multilocus approach to levels-of-selection and neighbor-modulated-fitness approaches in social evolution; (3) highlight the equivalence between genetical hitchhiking and kin selection; (4) demonstrate that the multilocus methodology allows for social evolutionary analyses involving coevolution of multiple traits and genetical associations between nonrelatives, including individuals of different species; (5) show that this methodology helps solve problems of dynamic sufficiency in social evolution theory; (6) form links between invasion criteria in multilocus systems and Hamilton's rule of kin selection; (7) illustrate the generality and exactness of Hamilton's rule, which has previously been described as an approximate, heuristic result.

  9. Inoculation Response of Legumes in Relation to the Number and Effectiveness of Indigenous Rhizobium Populations

    PubMed Central

    Singleton, P. W.; Tavares, J. W.

    1986-01-01

    The response of legumes to inoculation with rhizobia can be affected by many factors. Little work has been undertaken to examine how indigenous populations or rhizobia affect this response. We conducted a series of inoculation trials in four Hawaiian soils with six legume species (Glycine max, Vigna unguiculata, Phaseolus lunatus, Leucaena leucocephala, Arachis hypogaea, and Phaseolus vulgaris) and characterized the native rhizobial populations for each species in terms of the number and effectiveness of the population for a particular host. Inoculated plants had, on average, 76% of the nodules formed by the inoculum strain, which effectively eliminated competition from native strains as a variable between soils. Rhizobia populations ranged from less than 6 × 100/g of soil to 1 × 104/g of soil. The concentration of nitrogen in shoots of inoculated plants was not higher than that in uninoculated controls when the most probable number MPN counts of rhizobia were at or above 2 × 101/g of soil unless the native population was completely ineffective. Tests of random isolates from nodules of uninoculated plants revealed that within most soil populations there was a wide range of effectiveness for N2 fixation. All populations had isolates that were ineffective in fixing N2. The inoculum strains generally did not fix more N2 than the average isolate from the soil population in single-isolate tests. Even when the inoculum strain proved to be a better symbiont than the soil rhizobia, there was no response to inoculation. Enhanced N2 fixation after inoculation was related to increased nodule dry weights. Although inoculation generally increased nodule number when there were less than 1 × 102 rhizobia per g of soil, there was no corresponding increase in nodule dry weight when native populations were effective. Most species compensated for reduced nodulation in soils with few rhizobia by increasing the size of nodules and therefore maintaining a nodule dry weight similar

  10. Sequence-based genotyping of hepatitis B virus in general population

    PubMed Central

    Karimi, Ali; Moezzi, Ma’soumeh; Imani, Reza

    2015-01-01

    Background: Hepatitis B Virus (HBV) causes acute and chronic liver disease worldwide. HBV has eight genotypes (A to H) which is the reflection of its genome with their characteristic geographical distribution. Each genotype could have different pathogenic and therapeutic characteristics. There have been few records on HBV genotyping in general population from our region. This study aimed to determine hepatitis B genotypes using sequencing in the general population of Shahrekord, a Southwestern region of Iran. Methods: A total of 3000 serum samples (cluster sampling method) were enrolled from general population tested for HBsAg using ELISA. Using appropriate extraction kit, HBV DNA was extracted from HBsAg positive samples and each was subjected to nested PCR for detection of HBV DNA. Finally, using sequencing, the samples were used for HBV genotyping. Data were analyzed by SPSS 19 using descriptive statistics, chi square, and Fisher’s exact test. P-value < 0.05 was considered as the level of significance. Results: Out of 3000 serum samples, 40 (1.3%) were positive for HBsAg. HBV DNA was detected in 10 out of 40 (25%) of the samples studied. Genotype D was the predominant HBV type found in all of these 10 HBV positive samples. Conclusion: Genotype D is probably the predominant HBV type in our region. PMID:26000259

  11. A novel biomarker panel for irritable bowel syndrome and the application in the general population

    PubMed Central

    Mujagic, Zlatan; Tigchelaar, Ettje F.; Zhernakova, Alexandra; Ludwig, Thomas; Ramiro-Garcia, Javier; Baranska, Agnieszka; Swertz, Morris A.; Masclee, Ad A. M.; Wijmenga, Cisca; van Schooten, Frederik J.; Smolinska, Agnieszka; Jonkers, Daisy M. A. E.

    2016-01-01

    Biological markers that measure gut health and diagnose functional gastro-intestinal (GI) disorders, such as irritable bowel syndrome (IBS), are lacking. The objective was to identify and validate a biomarker panel associated with the pathophysiology of IBS that discriminates IBS from healthy controls (HC), and correlates with GI symptom severity. In a case-control design, various plasma and fecal markers were measured in a cohort of 196 clinical IBS patients and 160 HC without GI symptoms. A combination of biomarkers, which best discriminates between IBS and HC was identified and validated in an independent internal validation set and by permutation testing. The correlation between the biomarker panel and GI symptom severity was tested in IBS patients and in a general population cohort of 958 subjects. A set of 8 biomarker panel was identified to discriminate IBS from HC with high sensitivity (88.1%) and specificity (86.5%). The results for the IBS subtypes were comparable. Moreover, a moderate correlation was found between the biomarker panel and GI symptom scores in the IBS (r = 0.59, p < 0.001) and the general population cohorts (r = 0.51, p = 0.003). A novel multi-domain biomarker panel has been identified and validated, which correlated moderately to GI symptom severity in IBS and general population subjects. PMID:27263852

  12. Body mass index and blood glucose in psychiatric and general practice populations

    PubMed Central

    McAvoy, Sarah; Cordiner, Matthew; Kelly, Jackie; Chiwanda, Laura; Jefferies, Christine; Miller, Kirsteen; Shajahan, Polash

    2016-01-01

    Aims and method Using a retrospective observational approach, we aimed to discern whether there was a difference in metabolic parameters between psychiatric and general practice populations in the same locality. Second, we aimed to establish differences in metabolic parameters of patients taking olanzapine, clozapine or aripiprazole. Results Patients with psychiatric illness had a body mass index (BMI) comparable to that of the general practice population (28.7 v. 29.7 kg/m2), but blood glucose was significantly lower in the general practice population (4.8 v. 6.1 mmol/L). Olanzapine was associated with the lowest BMI (26.1 kg/m2) and aripiprazole the highest (32.2 kg/m2), with no difference in blood glucose between antipsychotics. Clinical implications Awareness of environmental factors and how they affect individuals is important and medications are not the only cause of metabolic effects. There may be a channelling bias present, meaning practitioners are cognisant of potential metabolic effects prior to prescribing. Overall monitoring of physical health is important regardless of potential cause. PMID:27280032

  13. Explanations of sleep paralysis among Egyptian college students and the general population in Egypt and Denmark.

    PubMed

    Jalal, Baland; Simons-Rudolph, Joseph; Jalal, Bamo; Hinton, Devon E

    2014-04-01

    This cross-cultural study compared explanations of sleep paralysis (SP) in two countries and two groups with different levels of education in one country. Comparisons were made between individuals having experienced SP at least once in a lifetime from Cairo, Egypt (n = 89), Copenhagen, Denmark (n = 59), and the American University in Cairo, Egypt (n = 44). As hypothesized, participants from the general Egyptian population were more likely to endorse supernatural causal explanation of their SP compared to participants from Denmark; participants from the American University in Cairo were less likely to endorse supernatural causes of their SP compared to participants from the general Egyptian population. Moreover, participants from the American University in Cairo were marginally significantly more likely to endorse supernatural causes of their SP compared to participants from Denmark. Additionally, we explored which culturally bound explanations and beliefs about SP existed in Egypt and Denmark. We found that nearly half (48%) of the participants from the general Egyptian population believed their SP to be caused by the Jinn, a spirit-like creature with roots in Islamic tradition, which constitutes a culturally bound interpretation of the phenomenology of SP in this region of the world. Case studies are presented to illustrate these findings.

  14. A novel biomarker panel for irritable bowel syndrome and the application in the general population.

    PubMed

    Mujagic, Zlatan; Tigchelaar, Ettje F; Zhernakova, Alexandra; Ludwig, Thomas; Ramiro-Garcia, Javier; Baranska, Agnieszka; Swertz, Morris A; Masclee, Ad A M; Wijmenga, Cisca; van Schooten, Frederik J; Smolinska, Agnieszka; Jonkers, Daisy M A E

    2016-01-01

    Biological markers that measure gut health and diagnose functional gastro-intestinal (GI) disorders, such as irritable bowel syndrome (IBS), are lacking. The objective was to identify and validate a biomarker panel associated with the pathophysiology of IBS that discriminates IBS from healthy controls (HC), and correlates with GI symptom severity. In a case-control design, various plasma and fecal markers were measured in a cohort of 196 clinical IBS patients and 160 HC without GI symptoms. A combination of biomarkers, which best discriminates between IBS and HC was identified and validated in an independent internal validation set and by permutation testing. The correlation between the biomarker panel and GI symptom severity was tested in IBS patients and in a general population cohort of 958 subjects. A set of 8 biomarker panel was identified to discriminate IBS from HC with high sensitivity (88.1%) and specificity (86.5%). The results for the IBS subtypes were comparable. Moreover, a moderate correlation was found between the biomarker panel and GI symptom scores in the IBS (r = 0.59, p < 0.001) and the general population cohorts (r = 0.51, p = 0.003). A novel multi-domain biomarker panel has been identified and validated, which correlated moderately to GI symptom severity in IBS and general population subjects. PMID:27263852

  15. Explanations of sleep paralysis among Egyptian college students and the general population in Egypt and Denmark.

    PubMed

    Jalal, Baland; Simons-Rudolph, Joseph; Jalal, Bamo; Hinton, Devon E

    2014-04-01

    This cross-cultural study compared explanations of sleep paralysis (SP) in two countries and two groups with different levels of education in one country. Comparisons were made between individuals having experienced SP at least once in a lifetime from Cairo, Egypt (n = 89), Copenhagen, Denmark (n = 59), and the American University in Cairo, Egypt (n = 44). As hypothesized, participants from the general Egyptian population were more likely to endorse supernatural causal explanation of their SP compared to participants from Denmark; participants from the American University in Cairo were less likely to endorse supernatural causes of their SP compared to participants from the general Egyptian population. Moreover, participants from the American University in Cairo were marginally significantly more likely to endorse supernatural causes of their SP compared to participants from Denmark. Additionally, we explored which culturally bound explanations and beliefs about SP existed in Egypt and Denmark. We found that nearly half (48%) of the participants from the general Egyptian population believed their SP to be caused by the Jinn, a spirit-like creature with roots in Islamic tradition, which constitutes a culturally bound interpretation of the phenomenology of SP in this region of the world. Case studies are presented to illustrate these findings. PMID:24084761

  16. Pet veterinarians have no increased risk of hepatitis E compared to the general population.

    PubMed

    Mesquita, J R; Valente-Gomes, G; Conceição-Neto, N; Nascimento, M S J

    2014-06-01

    The discovery of autochthonous hepatitis E in industrialized countries associated to genotype 3 has changed substantially the understanding about hepatitis E virus (HEV) circulation. In these countries transmission has been associated to the consumption and direct contact to swine, a well-known reservoir for HEV. More animal reservoirs for HEV might exist since antibodies to HEV have been detected in other animal species, such as dogs and cats. Given the intimate contact between these pets and humans, the potential zoonotic HEV transmission from dogs and cats deserves to be explored. To address this issue, 493 sera from pet veterinarians (373) and matched general population (120) were tested for the presence of anti-HEV IgG using a commercial ELISA. Antibodies to HEV were found in 9.9% veterinarians and 13.3% general population. No statistically significant difference was found between these two groups showing that pet veterinarians have no increased risk to hepatitis E compared to the general population. PMID:24610550

  17. Smoking Initiation, Tobacco Product Use, and Secondhand Smoke Exposure Among General Population and Sexual Minority Youth, Missouri, 2011–2012

    PubMed Central

    McElroy, Jane A.; Everett, Kevin D.

    2014-01-01

    Introduction Research indicates disparities in risky health behaviors between heterosexual and sexual minority (referred to as LGBQ; also known as lesbian, gay, bisexual, queer, and questioning) youth. Limited data are available for tobacco-use–related behaviors beyond smoking status. We compared data on tobacco age of initiation, product use, and secondhand smoke exposure between general population and LGBQ youth. Methods Data for general population youth were from the statewide, representative 2011 Missouri Youth Tobacco Survey, and data for LGBQ youth were from the 2012 Out, Proud and Healthy survey (collected at Missouri Pride Festivals). Age-adjusted Cochran-Mantel-Haenszel tests were used to examine differences between general population (N = 1,547) and LGBQ (N = 410) youth, aged 14 to 18 years. Logistic regression models identified variables associated with current smoking. Results The 2 groups differed significantly on many tobacco-use–related factors. General population youth initiated smoking at a younger age, and LGBQ youth did not catch up in smoking initiation until age 15 or 16. LGBQ youth (41.0%) soon surpassed general population youth (11.2%) in initiation and proportion of current smokers. LGBQ youth were more likely to use cigars/cigarillos, be poly-tobacco users, and be exposed to secondhand smoke (SHS) in a vehicle (for never smokers). Older age (odds ratio [OR] = 1.39, 95% confidence interval [95% CI] = 1.18–1.62), female sex (OR = 1.64, 95% CI = 1.13–2.37), LGBQ identity (OR = 3.86, 95% CI = 2.50–5.94), other tobacco product use (OR = 8.67, 95% CI = 6.01–12.51), and SHS exposure in a vehicle (OR = 5.97, 95% CI = 3.83–9.31) all significantly increased the odds of being a current smoker. Conclusion This study highlights a need for the collection of data on sexual orientation on youth tobacco surveys to address health disparities among LGBQ youth. PMID:24995655

  18. [Influence of relative humidity on the Adoxophyes orana experimental population].

    PubMed

    Sun, Li; Sun, Rui-hong; Qiu, Gui-sheng; Yan, Wen-tao; Zhang, Huai-jiang

    2014-12-01

    In order to explore the effects of relative humidity (RH) on the population growth of summer fruit tortrix moth Adoxophyes orana, the development, survival, fecundity and longevity of A. orana were assessed at 6 different constant humidities (40%, 50%, 60%, 70%, 80% and 90%), (25 +/- 1) degrees C and a photoperiod of 12L:12D in the laboratory. The results showed that immature developmental time was gradually shortened with the increasing humidity at 40%-90% RH, ranged from 30.31 d at 40% RH to 25.87 d at 90% RH. However, the survival rate for immature moth was gradually increased from 40% RH to 90% RH. Hatchability was inhibited significantly by low humidity and the lowest was 39.3% at 40% RH. And at 80% RH, the longevity of adults was the longest, the oviposition was the most (110.8 eggs per female) , and the survival rates for eggs and larvae were the highest. It resulted in the highest net reproductive rate (R0=26.46) and intrinsic rate of increase (r(m) = 0.1018). In conclusion, the development and fecundity of A. orana were promoted and improved at the higher humidity.

  19. Relation Between Near Work and Myopia Progression in Student Population

    PubMed Central

    Muhamedagic, Lejla; Muhamedagic, Belma; Halilovic, Emina Alimanovic; Halimic, Jasmina Alajbegovic; Stankovic, Aleksa; Muracevic, Bedrana

    2014-01-01

    Aim To determine relation between near work and myopia progression in student population. Causes of myopia occurrence are not sufficiently explained. Methods This retrospective-prospective, descriptive research included 100 students with verified myopia up to -3 Dsph. Ophthalmological examination and measurement diopter-hours variable (Dh) were done twice, in the period from January 2011 until January 2012. Results A multivariate regression analysis of impact on the difference of distance visual acuity without correction to the right and left eye and difference of automatic computer refractometry in cycloplegia of both eyes indicates that, diopter-hours variable (Dh) had statistically significant impact on increase of distance visual acuity difference (right eye OR: I measurement–Dh 1.489, II measurement–Dh 1.544, p<0.05; left eye OR: I measurement–Dh 1.602, II measurement–Dh 1.538, p<0.05) and automatic computer refractometry in cycloplegia (right eye OR: I measurement 1.361, II measurement 1.493, p<0.05; left eye OR: I measurement 0.931, II measurement 1.019, p<0.05) during both measurements. Conclusion Near work cause the increase of myopia. This research opened a perspective for other researches on the impact of near work on myopia. PMID:24944532

  20. Populations of Pratylenchus penetrans Relative to Decomposing Nitrogenous Soil Amendments

    PubMed Central

    Walker, J. T.

    1971-01-01

    Populations of Pratylenchus penetrans decreased in soil following addition of 70 and 700 ppm N in the form of nitrate, nitrite, organic nitrogen, or ammonium compounds. Nitrate was less effective than other nitrogen carriers. Population reduction is principally attributed to ammonification during decomposition. This hypothesis is supported by chromatographic analyses of soil atmospheres, survival of nematodes in pure CO₂ and N₂, inverse relationship of CO₂, content in amended soils to nematode populations, and direct relationship of NH₃-N content of amended soils to nematode populations. PMID:19322339

  1. Prevalence, survival analysis and multimorbidity of chronic diseases in the general veterinarian-attended horse population of the UK.

    PubMed

    Welsh, Claire E; Duz, Marco; Parkin, Timothy D H; Marshall, John F

    2016-09-01

    The average age of the global human population is increasing, leading to increased interest in the effects of chronic disease and multimorbidity on health resources and patient welfare. It has been posited that the average age of the general veterinarian-attended horse population of the UK is also increasing, and therefore it could be assumed that chronic diseases and multimorbidity would pose an increasing risk here also. However, evidence for this trend in ageing is very limited, and the current prevalence of many chronic diseases, and of multimorbidity, is unknown. Using text mining of first-opinion electronic medical records from seven veterinary practices around the UK, Kaplan-Meier and Cox proportional hazard modelling, we were able to estimate the apparent prevalence among veterinarian-attended horses of nine chronic diseases, and to assess their relative effects on median life expectancy following diagnosis. With these methods we found evidence of increasing population age. Multimorbidity affected 1.2% of the study population, and had a significant effect upon survival times, with co-occurrence of two diseases, and three or more diseases, leading to 6.6 and 21.3 times the hazard ratio compared to no chronic disease, respectively. Laminitis was involved in 74% of cases of multimorbidity. The population of horses attended by UK veterinarians appears to be aging, and chronic diseases and their co-occurrence are common features, and as such warrant further investigation. PMID:27544263

  2. Cognitive and Psychological Reactions of the General Population Three Months After the 2011 Tohoku Earthquake and Tsunami

    PubMed Central

    Kyutoku, Yasushi; Tada, Ryoko; Umeyama, Takahiko; Harada, Kenji; Kikuchi, Senichiro; Watanabe, Eiju; Liegey-Dougall, Angela; Dan, Ippeita

    2012-01-01

    Background The largest earthquake on record in Japan (magnitude 9.0) occurred on March 11, 2011, and the subsequent tsunami devastated the Pacific coast of Northern Japan. These further triggered the Fukushima I nuclear power plant accidents. Such a hugely complex disaster inevitably has negative psychological effects on general populations as well as on the direct victims. While previous disaster studies enrolled descriptive approaches focusing on direct victims, the structure of the psychological adjustment process of people from the general population has remained uncertain. The current study attempted to establish a path model that sufficiently reflects the early psychological adaptation process of the general population to large-scale natural disasters. Methods and Findings Participants from the primary disaster area (n = 1083) and other areas (n = 2372) voluntarily participated in an online questionnaire study. By constructing path models using a structural equation model procedure (SEM), we examined the structural relationship among psychological constructs known related to disasters. As post-traumatic stress symptoms (PTS) were significantly more present in people in the primarily affected area than in those in secondary- or non-affected areas, the path models were constructed for the primary victims. The parsimoniously depicted model with the best fit was achieved for the psychological-adjustment centered model with quality of life (QoL) as a final outcome. Conclusion The paths to QoL via negative routes (from negative cognitive appraisal, PTS, and general stress) were dominant, suggesting the importance of clinical intervention for reducing negative cognitive appraisal, and for caring for general stress and PTS to maintain QoL at an early stage of psychological adaptation to a disaster. The model also depicted the presence of a positive route where positive cognitive appraisal facilitates post-traumatic growth (PTG) to achieve a higher Qo

  3. The role of general practitioners in prevention of depression-related suicides.

    PubMed

    Rihmer, Zoltan; Dome, Peter; Gonda, Xenia

    2012-12-01

    Suicide is a ubiquitous phenomenon present in every country, and a function of the constellation of multiple risk and protective factors. The relatively low occurrence of attempted and completed suicide in the general community makes its research and consequentially prediction and prevention difficult, however, suicide events are common among psychiatric patients who contact their general practitioners some weeks or months before their suicidal act. Major depressive episode is the most common current psychiatric diagnosis among suicide victims and attempters (56-87%), and successful acute and long-term treatment of depression significantly reduces the risk of suicidal behaviour even in this high-risk population. The point prevalence of unipolar and bipolar major depressive episode encountered in general practice is more than 10% but unfortunately about half of these cases remain unrecognized, untreated or mistreated. As over half of all suicide victims contact their general practitioners within four weeks before their death, primary care physicians play a key role in suicide prediction and prevention. Several large-scale community studies show that education of general practitioners and other medical professionals on the recognition and appropriate pharmacotherapy of depression, particularly in combination with psycho-social interventions and public education significantly improves identification and treatment of depression and consequentially reduces the rate of completed and attempted suicide in the areas served by trained doctors.

  4. Patterns of Hamstring Muscle Tears in the General Population: A Systematic Review

    PubMed Central

    Kuske, Barbara; Hamilton, David F.; Pattle, Sam B.; Simpson, A. Hamish R. W.

    2016-01-01

    Background Hamstring tears are well recognised in the sporting population. Little is known about these injuries in the general population. Purpose Evaluating the rates, patterns and risk factors of non-sporting hamstring tears, compared to sporting related hamstring tears. Data Sources MEDLINE, EMBASE, CINAHL, and the Cochrane Central Register of Controlled Trials (1989–2015). Study Selection Studies reporting patients with a grade 2 or 3 hamstring muscle tear, identified clinically, confirmed by MRI imaging or direct visualisation during surgical exploration. Data Synthesis 144 sets of linked data were extracted for analysis. Most injuries were in males (81.3%), where mean age at injury was lower (30.2, 95% CI 29.1–31.3) than in females (35.4, 95% CI 32.4–38.4) p = 0.06. Key differences were found in the proportion of non-sporting injuries in patients under and over the age 40 (p = 0.001). The proportion of non-sporting injuries was significantly higher in females compared to males (25.9% female non-sporting injuries, versus 8.5% male; p = 0.02). Avulsions were more frequently reported in non-sporting activities (70.5%). The proportion of such injuries was notably higher in females, though this failed to meet significance (p = 0.124). Grouped by age category a bimodal distribution was noted, with the proportion of avulsions greater in younger (age <15) and older patients (age > 40) (p = 0.008). 86.8% of patients returned to pre-injury activity levels with a similar frequency across all study variables; age, activity (sporting vs non-sporting) and injury type (avulsion vs tear). Conclusion This review highlights a proportion of adults suffering grade 2 or 3 hamstring injuries from activities other than the classic sports trauma. The majority of these non-sporting injuries were avulsion injuries that clustered in older female and skeletally immature patients suggesting a potential link to bone mineral density. PMID:27144648

  5. Desphospho-uncarboxylated matrix Gla protein is associated with increased aortic stiffness in a general population.

    PubMed

    Mayer, O; Seidlerová, J; Wohlfahrt, P; Filipovský, J; Vaněk, J; Cífková, R; Windrichová, J; Topolčan, O; Knapen, M H J; Drummen, N E A; Vermeer, C

    2016-07-01

    Matrix Gla protein (MGP), a natural inhibitor of calcification, strongly correlates with the extent of coronary calcification. Vitamin K is the essential cofactor for the activation of MGP. The nonphosphorylated-uncarboxylated isoform of MGP (dp-ucMGP) reflects the status of this vitamin. We investigated whether there is an association between dp-ucMGP and stiffness of elastic and muscular-type large arteries in a random sample from the general population. In a cross-sectional design, we analyzed 1087 subjects from the Czech post-MONICA study. Aortic and femoro-popliteal pulse wave velocities (PWVs) were measured using a Sphygmocor device. Dp-ucMGP concentrations were assessed in freshly frozen samples by enzyme-linked immunosorbent assay methods using the InaKtif MGP iSYS pre-commercial kit developed by IDS and VitaK. Aortic PWV significantly (P<0.0001) increased across the dp-ucMGP quartiles. After adjustment for all potential confounders, aortic PWV independently correlated with dp-ucMGP (with beta coefficient (s.d.) 11.61 (5.38) and P-value=0.031). In a categorized manner, subjects in the top quartile of dp-ucMGP (⩾ 671 pmol l(-1)) had a higher risk of elevated aortic PWV, with corresponding adjusted odds ratio (95% confidence interval) 1.73 (1.17-2.5). In contrast, no relation between dp-ucMGP and femoro-popliteal PWV was found. In conclusion, increased dp-ucMGP, which is a circulating biomarker of vitamin K status and vascular calcification, is independently associated with aortic stiffness, but not with stiffness of distal muscular-type arteries.

  6. Association between processing speed and subclinical psychotic symptoms in the general population: focusing on sex differences.

    PubMed

    Rössler, Wulf; Ajdacic-Gross, Vladeta; Müller, Mario; Rodgers, Stephanie; Kawohl, Wolfram; Haker, Helene; Hengartner, Michael P

    2015-08-01

    Evidence is growing that persons along the schizophrenia spectrum, i.e., those who also display subclinical psychotic symptoms, exhibit deficits across a broad range of neuropsychological domains. Because sex differences in the association between cognitive deficits and psychosis have thus far been mostly neglected, we believe that ours is the first study specifically focused upon those differences when examining the relationship between subclinical psychosis and processing speed. Using a sample of 213 persons from the general population from Zurich, Switzerland, psychotic symptoms were assessed with three different questionnaires including the Schizotypal Personality Questionnaire, an adaptation of the Structured Interview for Assessing Perceptual Anomalies, and the Paranoia Checklist. Processing speed was assessed with the WAIS digit-symbol coding test. Two higher-order psychosis domains were factor-analytically derived from the various psychosis subscales and then subjected to a series of linear regression analyses. The results demonstrate that in both men and women associations between subclinical psychosis domains and processing speed were weak to moderate (β ranging from -0.18 to -0.27; all p<0.05). However, we found no sex-differences in the interrelation of subclinical psychosis and processing speed (ΔR(2)<0.005; p>0.30). In conclusion, it appears that sex differences in psychosis manifest themselves only at the high end of the continuum (full-blown schizophrenia) and not across the sub-threshold range. The small magnitude of the effects reported herein conforms to the etiopathology of the disorder. Since schizophrenia and related disorders from the spectrum are assumed to be multifactorial diseases, it follows that many etiological components of small effect are involved. PMID:26070411

  7. Desphospho-uncarboxylated matrix Gla protein is associated with increased aortic stiffness in a general population.

    PubMed

    Mayer, O; Seidlerová, J; Wohlfahrt, P; Filipovský, J; Vaněk, J; Cífková, R; Windrichová, J; Topolčan, O; Knapen, M H J; Drummen, N E A; Vermeer, C

    2016-07-01

    Matrix Gla protein (MGP), a natural inhibitor of calcification, strongly correlates with the extent of coronary calcification. Vitamin K is the essential cofactor for the activation of MGP. The nonphosphorylated-uncarboxylated isoform of MGP (dp-ucMGP) reflects the status of this vitamin. We investigated whether there is an association between dp-ucMGP and stiffness of elastic and muscular-type large arteries in a random sample from the general population. In a cross-sectional design, we analyzed 1087 subjects from the Czech post-MONICA study. Aortic and femoro-popliteal pulse wave velocities (PWVs) were measured using a Sphygmocor device. Dp-ucMGP concentrations were assessed in freshly frozen samples by enzyme-linked immunosorbent assay methods using the InaKtif MGP iSYS pre-commercial kit developed by IDS and VitaK. Aortic PWV significantly (P<0.0001) increased across the dp-ucMGP quartiles. After adjustment for all potential confounders, aortic PWV independently correlated with dp-ucMGP (with beta coefficient (s.d.) 11.61 (5.38) and P-value=0.031). In a categorized manner, subjects in the top quartile of dp-ucMGP (⩾ 671 pmol l(-1)) had a higher risk of elevated aortic PWV, with corresponding adjusted odds ratio (95% confidence interval) 1.73 (1.17-2.5). In contrast, no relation between dp-ucMGP and femoro-popliteal PWV was found. In conclusion, increased dp-ucMGP, which is a circulating biomarker of vitamin K status and vascular calcification, is independently associated with aortic stiffness, but not with stiffness of distal muscular-type arteries. PMID:26016598

  8. Association between dietary factors and plasma fetuin-A concentrations in the general population.

    PubMed

    Nimptsch, Katharina; Janke, Jürgen; Pischon, Tobias; Linseisen, Jakob

    2015-10-28

    Circulating fetuin-A, a novel marker for hepatic fat accumulation, has been related to a higher risk of type 2 diabetes and cardiovascular diseases in a growing number of prospective studies. However, little is known about dietary determinants of fetuin-A concentrations in the general population. Therefore, we aimed to investigate the association between dietary intake of energy, energy-providing nutrients, alcohol and major food groups and plasma fetuin-A concentrations in the Bavarian Food Consumption Survey II. Dietary intake was assessed by three 24-h dietary recalls, and plasma concentrations of fetuin-A were measured in 558 adults (18-81 years). After multivariable adjustment for lifestyle factors and body fatness, higher energy intake was nonsignificantly associated with higher fetuin-A concentrations (per 2092 kJ/d (500 kcal/d) 3·7 µg/ml, 95 % CI -0·5, 7·8 µg/ml). There was no clear association between energy-providing nutrients and fetuin-A concentrations. Higher alcohol intake was associated with lower fetuin-A concentrations (P trend 0·003): mean fetuin-A concentrations were 324 (95 % CI 313, 335) µg/ml in non-drinkers, and with 293 (95 % CI 281, 306) µg/ml significantly lower in participants who drank ≥30 g alcohol per d. Mean fetuin-A concentrations decreased across quintiles of milk and dairy product intake (lowest quintile 319 (95 % CI 309, 330) µg/ml; highest quintile 304 (95 % CI 293, 314) µg/ml; P trend 0·03), and each 150-g increment in milk/dairy products per d was associated with 5·6 (95 % CI -9·6, -1·5) µg/ml lower fetuin-A. Dietary intakes of vegetables, meat or fish were not associated with fetuin-A concentrations. Because of the preventive potential of our findings, further exploration is warranted. PMID:26316198

  9. Probing Strong-field General Relativity with Gravitational Waves

    NASA Astrophysics Data System (ADS)

    Pretorius, Frans

    We are on the verge of a new era in astrophysics as a world-wide effort to observe the universe with gravitational waves takes hold---ground based laser interferometers (Hz to kHz), pulsar timing (micro to nano Hz), measurements of polarization of the cosmic microwave background (sub-nano Hz), and the planned NASA/ESA mission LISA (.1 mHz to .1 Hz). This project will study the theoretical nature of gravitational waves (GWs) emitted by two sources in the LISA band, namely supermassive-black-hole (SMBH) binary mergers, and extreme-mass-ratio-inspirals (EMRI's)---the merger of a stellar mass black hole, neutron star, or white dwarf with a SMBH. The primary goal will be to ascertain how well LISA, by observing these sources, could answer the following related questions about the fundamental nature of strong-field gravity: Does Einstein's theory of general relativity (GR) describe the geometry of black holes in the universe? What constraints can GW observations of SMBH mergers and EMRIs place on alternative theories of gravity? If there are deviations from GR, are there statistics that could give indications of a deviation if sources are detected using a search strategy based solely on GR waveforms? The primary reasons for focusing on LISA sources to answer these questions are (a) binary SMBH mergers could be detected by LISA with exquisitely high signal-to- noise, allowing enough parameters of the system to be accurately extracted to perform consistency checks of the underlying theory, (b) EMRIs will spend numerous orbits close to the central black hole, and thus will be quite sensitive to even small near-horizon deviations from GR. One approach to develop the requisite knowledge and tools to answer these questions is to study a concrete, theoretically viable alternative to GR. We will focus on the dynamical variant of Chern-Simons modified gravity (CSMG), which is interesting for several reasons, chief among which are (1) that CSMG generically arises in both string

  10. Prevalence and Trends of the Abdominal Aortic Aneurysms Epidemic in General Population - A Meta-Analysis

    PubMed Central

    Li, Xi; Zhao, Ge; Zhang, Jian; Duan, Zhiquan; Xin, Shijie

    2013-01-01

    Objective To conduct a meta-analysis assessing the prevalence and trends of the abdominal aortic aneurysms (AAA) epidemic in general population. Method Studies that reported prevalence rates of AAA from the general population were identified through MEDLINE, EMBASE, Web of Science, and reference lists for the period between 1988 and 2013. Studies were included if they reported prevalence rates of AAA in general population from the community. In stratified analyses possible sources of bias, including areas difference, age, gender and diameter of aneurysms were examined. Publication bias was assessed with Egger's test method. Results 56 studies were identified. The overall pooled prevalence of AAA was 4.8% (4.3%, 5.3%). Stratified analyses showed the following results, areas difference: America 2.2% (2.2%, 2.2%), Europe 2.5% (2.4%, 2.5%), Australia 6.7% (6.5%, 7.0%), Asia 0.5% (0.3%, 0.7%); gender difference: male 6.0% (5.3%, 6.7%), female 1.6% (1.2%, 1.9%); age difference: 55–64years 1.3% (1.2%, 1.5%), 65–74 years 2.8% (2.7%, 2.9%), 75–84 years1.2%(1.1%, 1.3%), ≥85years0.6% (0.4%, 0.7%); aortic diameters difference: 30–39 mm, 3.3% (2.8%, 3.9%), 40–49 mm,0.7% (0.4%,1.0%), ≥50 mm, 0.4% (0.3%, 0.5%). The prevalence of AAA has decreased in Europe from 1988 to 2013. Hypertension, smoking, coronary artery disease, dyslipidemia, respiratory disease, cerebrovascular disease, claudication and renal insufficiency were risk factors for AAA in Europe. Conclusion AAA is common in general population. The prevalence of AAA is higher in Australia than America and Europe. The pooled prevalence in western countries is higher than the Asia. Future research requires a larger database on the epidemiology of AAA in general population. PMID:24312543

  11. The seduction of general practice and illegitimate birth of an expanded role in population health care.

    PubMed

    Buetow, Stephen; Docherty, Barbara

    2005-08-01

    To reduce health inequalities and improve quality in health care, health policy initiatives in countries including New Zealand and the United Kingdom are expecting general practice to share responsibilities for a population approach to health care. This is giving increased emphasis to preventative care, including health promotion. Reasoned debate on this policy is overdue, not least in New Zealand, where clinicians within general practice appear to have been seduced by the lack of clarity in health policy into accepting this policy without question. They appear to disregard implications of the policy for redefining the nature and scope of their discipline (and of public health), including their own role as providers of personal care. This paper suggests that a population health approach is inappropriate in general practice when this approach weakens personal care and involves health promotion activity of unknown safety and effectiveness. The example of intentional weight loss to reduce overweight is used to illustrate these issues. We argue for a restricted range of general practice services.

  12. White matter hyperintensities and imaging patterns of brain ageing in the general population.

    PubMed

    Habes, Mohamad; Erus, Guray; Toledo, Jon B; Zhang, Tianhao; Bryan, Nick; Launer, Lenore J; Rosseel, Yves; Janowitz, Deborah; Doshi, Jimit; Van der Auwera, Sandra; von Sarnowski, Bettina; Hegenscheid, Katrin; Hosten, Norbert; Homuth, Georg; Völzke, Henry; Schminke, Ulf; Hoffmann, Wolfgang; Grabe, Hans J; Davatzikos, Christos

    2016-04-01

    -AD variance. Multivariable regression showed significant relationship between white matter hyperintensities volume and hypertension (P = 0.001), diabetes mellitus (P = 0.023), smoking (P = 0.002) and education level (P = 0.003). The only significant association with cognitive tests was with the immediate recall of the California verbal and learning memory test. No significant association was present with the APOE genotype. These results support the hypothesis that white matter hyperintensities contribute to patterns of brain atrophy found in beyond-normal brain ageing in the general population. White matter hyperintensities also contribute to brain atrophy patterns in regions related to Alzheimer's disease dementia, in agreement with their known additive role to the likelihood of dementia. Preventive strategies reducing the odds to develop cardiovascular disease and white matter hyperintensities could decrease the incidence or delay the onset of dementia.

  13. BOOK REVIEW: A First Course in General Relativity (Second Edition) A First Course in General Relativity (Second Edition)

    NASA Astrophysics Data System (ADS)

    Poisson, Eric

    2010-05-01

    A few years ago, in my review of Sean Carroll's book in Classical and Quantum Gravity [1], I wrote that while the 1970s was the decade of Weinberg [2] and Misner, Thorne and Wheeler [3], and while the eighties was the decade of Schutz [4] and Wald [5], the 2000s was clearly the decade of Hartle [6] and Carroll [7]. In my opinion, these books continue to stand out in the surprisingly dense crowd of introductory textbooks on general relativity. At the dawn of this new decade I look forward to see what fresh pedagogical insights will be produced next, and who will be revealed as the winners of the 2010s. It is, of course, much too early to tell, but Schutz is back, and he will set the standard just as he did back in 1985. This is the long-awaited second edition of his `First Course', a short, accessible, and very successful introduction to general relativity. The changes from the first edition are modest: Schutz wisely refrained from bloating the text with new topics, and limited himself to updating his discussion of gravitational-wave sources and detectors, neutron-star and black-hole astrophysics, and suggestions for further reading. Most importantly, he completely rewrote the chapter on cosmology, a topic that has evolved enormously since the first edition. The book begins in chapter 1 with a beautiful review of special relativity that emphasizes spacetime geometry and stays away from an algebraic approach based on the Lorentz transformation, which appears only later in the chapter. This is followed up in chapters 2 and 3 with an introduction to vector and tensor analysis in flat spacetime. The point of view is modern (tensors are defined as linear mapping of vectors and one-forms into real numbers) but the presentation is very accessible and avoids an overload of mathematical fine print. In chapter 4 the book introduces the spacetime description of fluids; it is here that the energy-momentum tensor makes its first appearance. The move to curved spacetime is

  14. [Population Education: Its Goals, Related Guidelines, and Considerations for Curriculum.

    ERIC Educational Resources Information Center

    Jayasuriya, J. E.

    Many countries today recognize the need to initiate a population education program within the school curriculum at all levels. In developing countries, many changes have been brought about by population increases. Enormous needs have been created for housing, schools, medical care, food, and employment. These needs, however, are not being met…

  15. A Student's Manual for A First Course in General Relativity

    NASA Astrophysics Data System (ADS)

    Scott, Robert B.

    2016-01-01

    Preface; 1. Special relativity; 2. Vector analysis in special relativity; 3. Tensor analysis in special relativity; 4. Perfect fluids in special relativity; 5. Preface to curvature; 6. Curved manifolds; 7. Physics in curved spacetime; 8. The Einstein field equations; 9. Gravitational radiation; 10. Spherical solutions for stars; 11. Schwarzschild geometry and black holes; 12. Cosmology; Appendix A. Acronyms and definitions; Appendix B. Useful results; References; Index.

  16. BOOK REVIEW Exact Space-Times in Einstein's General Relativity Exact Space-Times in Einstein's General Relativity

    NASA Astrophysics Data System (ADS)

    Lake, Kayll

    2010-12-01

    , Hoenselaers C and Herlt E 2003 Exact Solutions of Einstein's Field Equations (Second Edition) (Cambridge: Cambridge University Press) [2] Pretorius F and Israel W 1998 Class. Quantum Grav.15 2289 [3] Wiltshire D, Visser M and Scott S (ed) 2008 The Kerr Spacetime: Rotating Black Holes in General Relativity (Cambridge: Cambridge University Press) [4] Coley A, Hervik S and Pelavas N 2009 Class. Quantum Grav. 26 025013 [5] Plebański J and Krasiński A 2006 An Introduction to General Relativity and Cosmology (Cambridge: Cambridge University Press)

  17. Measuring social class differences in cancer patient survival: is it necessary to control for social class differences in general population mortality? A Finnish population-based study

    PubMed Central

    Dickman, P. W.; Auvinen, A.; Voutilainen, E. T.; Hakulinen, T.

    1998-01-01

    STUDY OBJECTIVES: Estimation of cancer patient survival by social class has been performed using observed, corrected (cause specific), and relative (with expected survival based on the national population) survival rates. Each of these measures are potentially biased and the optimal method is to calculate relative survival rates using social class specific death rates to estimate expected survival. This study determined the degree to which the choice of survival measure affects the estimation of social class differences in cancer patient survival. SETTING AND PARTICIPANTS: All Finnish residents diagnosed with at least one of 10 common malignant neoplasms during the period 1977-1985 were identified from the Finnish Cancer Registry and followed up for deaths to the end of 1992. DESIGN: Survival rates were calculated by site, sex, and age at 5, 10, and 15 years subsequent to diagnosis for each of three measures of survival; relative survival, corrected (cause specific) survival, and relative survival adjusted for social class differences in general mortality. Regression models were fitted to each set of rates for the first five years of follow up. MAIN RESULTS: The degree of variation in relative survival resulting from social class decreased, although did not disappear, after controlling for social class differences in general mortality. The results obtained using corrected survival were close to those obtained using relative survival with a social class correction. The differences between the three measures were largest when the proportion of deaths from other causes was large, for example, in cancers with high survival, among older patients, and for longer follow up times. CONCLUSIONS: Although each of the three measures gave comparable results, it is recommended that relative survival rates are used with expected survival adjusted for social class when studying social class variation in cancer patient survival. If this is not an available option, it is recommended

  18. Cadmium exposure and risk of prostate cancer: a meta-analysis of cohort and case-control studies among the general and occupational populations

    PubMed Central

    Chen, Cheng; Xun, Pengcheng; Nishijo, Muneko; Carter, Sue; He, Ka

    2016-01-01

    We aimed to evaluate the association of cadmium exposure with the risk of prostate cancer in both the general and occupational populations. Online database searches were performed for studies of prostate cancer risk and cadmium exposure. Twelve cohort studies (5 in the general, 7 in occupational populations) and 9 case-control studies (3 in the general, 6 in occupational populations) were identified. Five/seven cohort studies in the general and occupational populations consist of 78,263/13, 434 participants with a mean follow-up of 12.1/43.0 years, respectively. Case-control studies include 334 cases/670 controls in the general population, and 1,315 cases/4,477 controls in occupational populations. Comparing the highest to the lowest category of cadmium exposure in the general population, the weighted relative risk of prostate cancer incidence and mortality among cohort studies, and the weighted odds ratio in case-control studies were 1.05 (95%CI [0.91, 1.22]), 0.83 (95%CI [0.35, 1.98]), and 1.27 (95%CI [0.58,2.78]), respectively. For occupational populations, the weighted OR in case-control studies was 1.17 (95%CI [0.85, 1.62]), and the weighted standardized mortality ratio in cohort studies was 98 (95%CI [75, 126]). Accumulated epidemiological evidence does not support the hypothesis that cadmium exposure may increase the risk of prostate cancer in either the general or occupational populations. PMID:27174617

  19. The physics of anisotropic spheres in general relativity

    NASA Astrophysics Data System (ADS)

    Dev, Krsna

    2001-11-01

    We study the effects of anisotropic pressure on the properties of spherically symmetric, gravitationally bound spheres. We consider the full general-relativistic and Newtonian treatment of this problem and obtain exact solutions for various forms of the equation of state connecting the radial and tangential pressures. It is shown that pressure anisotropy can have significant effects on the structure and properties of both Newtonian and general relativistic spheres. We show that it is possible for Newtonian spheres to have an infinite core pressure without requiring the radius to be infinite and that there exists stable anisotropic spheres with adiabatic exponents less than 4/3. For general relativistic spheres we demonstrate that the maximum value of 2M/R can approach unity (2M/R < 8/9 for isotropic spheres) and the surface redshift can be arbitrarily large.

  20. Transient population dynamics: Relations to life history and initial population state

    USGS Publications Warehouse

    Koons, D.N.; Grand, J.B.; Zinner, B.; Rockwell, R.F.

    2005-01-01

    Most environments are variable and disturbances (e.g., hurricanes, fires) can lead to substantial changes in a population's state (i.e., age, stage, or size distribution). In these situations, the long-term (i.e., asymptotic) measure of population growth rate (??1) may inaccurately represent population growth in the short-term. Thus, we calculated the short-term (i.e., transient) population growth rate and its sensitivity to changes in the life-cycle parameters for three bird and three mammal species with widely varying life histories. Further, we performed these calculations for initial population states that spanned the entire range of possibilities. Variation in a population's initial net reproductive value largely explained the variation in transient growth rates and their sensitivities to changes in life-cycle parameters (all AICc ??? 6.67 units better than the null model, all R2 ??? 0.55). Additionally, the transient fertility and adult survival sensitivities tended to increase with the initial net reproductive value of the population, whereas the sub-adult survival sensitivity decreased. Transient population dynamics of long-lived, slow reproducing species were more variable and more different than asymptotic dynamics than they were for short-lived, fast reproducing species. Because ??1 can be a biased estimate of the actual growth rate in the short-term (e.g., 19% difference), conservation and wildlife biologists should consider transient dynamics when developing management plans that could affect a population's state, or whenever population state could be unstable.

  1. Language Generativity, Response Generalization, and Derived Relational Responding

    ERIC Educational Resources Information Center

    Stewart, Ian; McElwee, John; Ming, Siri

    2013-01-01

    Language generativity can be described as the ability to produce sentences never before said, and to understand sentences never before heard. One process often cited as underlying language generativity is response generalization. However, though the latter seems to promise a technical understanding of the former at a process level, an…

  2. Disformal transformations, veiled General Relativity and Mimetic Gravity

    NASA Astrophysics Data System (ADS)

    Deruelle, Nathalie; Rua, Josephine

    2014-09-01

    In this Note we show that Einstein's equations for gravity are generically invariant under ``disformations''. We also show that the particular subclass when this is not true yields the equations of motion of ``Mimetic Gravity''. Finally we give the ``mimetic'' generalization of the Schwarzschild solution.

  3. Disformal transformations, veiled General Relativity and Mimetic Gravity

    SciTech Connect

    Deruelle, Nathalie; Rua, Josephine E-mail: rua@cbpf.br

    2014-09-01

    In this Note we show that Einstein's equations for gravity are generically invariant under ''disformations''. We also show that the particular subclass when this is not true yields the equations of motion of ''Mimetic Gravity''. Finally we give the ''mimetic'' generalization of the Schwarzschild solution.

  4. Industrial Cooperative Training II. Curriculum Guide. General Related Study Units.

    ERIC Educational Resources Information Center

    Virginia Polytechnic Inst. and State Univ., Blacksburg. Div. of Vocational-Technical Education.

    Basic guidelines are offered for the teacher or coordinator who is working with second year Industrial Cooperative Training students (generally students at the twelfth grade level). The contents are organized into 12 units, with each unit including two to five lesson plans, transparencies (coded "T"), handouts (coded "H"), and a bibliography…

  5. Personality Factors Related to Career Satisfaction among General Practitioners.

    ERIC Educational Resources Information Center

    Schwartz, Robert H.; Shenoy, Sunil

    1994-01-01

    A survey of 150 general practice dentists examined the relationship between 6 career interests (scientific, artistic, social, enterprising, conventional, technical) and career satisfaction. Results are presented and compared with findings of other studies of dental students and practitioners. Results suggest that satisfied dentists tended to like…

  6. The self-reported health of U.S. flight attendants compared to the general population

    PubMed Central

    2014-01-01

    Background Few studies have examined the broad health effects of occupational exposures in flight attendants apart from disease-specific morbidity and mortality studies. We describe the health status of flight attendants and compare it to the U.S. population. In addition, we explore whether the prevalence of major health conditions in flight attendants is associated with length of exposure to the aircraft environment using job tenure as a proxy. Methods We surveyed flight attendants from two domestic U.S. airlines in 2007 and compared the prevalence of their health conditions to contemporaneous cohorts in the National Health and Nutrition Survey (NHANES), 2005-2006 and 2007-2008. We weighted the prevalence of flight attendant conditions to match the age distribution in the NHANES and compared the two populations stratified by gender using the Standardized Prevalence Ratio (SPR). For leading health conditions in flight attendants, we analyzed the association between job tenure and health outcomes in logistic regression models. Results Compared to the NHANES population (n =5,713), flight attendants (n = 4,011) had about a 3-fold increase in the age-adjusted prevalence of chronic bronchitis despite considerably lower levels of smoking. In addition, the prevalence of cardiac disease in female flight attendants was 3.5 times greater than the general population while their prevalence of hypertension and being overweight was significantly lower. Flight attendants reported 2 to 5.7 times more sleep disorders, depression, and fatigue, than the general population. Female flight attendants reported 34% more reproductive cancers. Health conditions that increased with longer job tenure as a flight attendant were chronic bronchitis, heart disease in females, skin cancer, hearing loss, depression and anxiety, even after adjusting for age, gender, body mass index (BMI), education, and smoking. Conclusions This study found higher rates of specific diseases in flight attendants

  7. Population-based preconception carrier screening: how potential users from the general population view a test for 50 serious diseases.

    PubMed

    Plantinga, Mirjam; Birnie, Erwin; Abbott, Kristin M; Sinke, Richard J; Lucassen, Anneke M; Schuurmans, Juliette; Kaplan, Seyma; Verkerk, Marian A; Ranchor, Adelita V; van Langen, Irene M

    2016-10-01

    With the increased international focus on personalized health care and preventive medicine, next-generation sequencing (NGS) has substantially expanded the options for carrier screening of serious, recessively inherited diseases. NGS screening tests not only offer reproductive options not previously available to couples, but they may also ultimately reduce the number of children born with devastating disorders. To date, preconception carrier screening (PCS) has largely targeted single diseases such as cystic fibrosis, but NGS allows the testing of many genes or diseases simultaneously. We have developed an expanded NGS PCS test for couples; simultaneously it covers 50 very serious, early-onset, autosomal recessive diseases that are untreatable. This is the first, noncommercial, population-based, expanded PCS test to be offered prospectively to couples in a health-care setting in Europe. So far, little is known about how potential users view such a PCS test. We therefore performed an online survey in 2014 among 500 people from the target population in the Netherlands. We enquired about their intention to take an expanded PCS test if one was offered, and through which provider they would like to see it offered. One-third of the respondents said they would take such a test were it to be offered. The majority (44%) preferred the test to be offered via their general practitioner (GP) and 58% would be willing to pay for the test, with a median cost of [euro ]75. Our next step is to perform an implementation study in which this PCS test will be provided via selected GPs in the Northern Netherlands.

  8. Population-based preconception carrier screening: how potential users from the general population view a test for 50 serious diseases

    PubMed Central

    Plantinga, Mirjam; Birnie, Erwin; Abbott, Kristin M; Sinke, Richard J; Lucassen, Anneke M; Schuurmans, Juliette; Kaplan, Seyma; Verkerk, Marian A; Ranchor, Adelita V; van Langen, Irene M

    2016-01-01

    With the increased international focus on personalized health care and preventive medicine, next-generation sequencing (NGS) has substantially expanded the options for carrier screening of serious, recessively inherited diseases. NGS screening tests not only offer reproductive options not previously available to couples, but they may also ultimately reduce the number of children born with devastating disorders. To date, preconception carrier screening (PCS) has largely targeted single diseases such as cystic fibrosis, but NGS allows the testing of many genes or diseases simultaneously. We have developed an expanded NGS PCS test for couples; simultaneously it covers 50 very serious, early-onset, autosomal recessive diseases that are untreatable. This is the first, noncommercial, population-based, expanded PCS test to be offered prospectively to couples in a health-care setting in Europe. So far, little is known about how potential users view such a PCS test. We therefore performed an online survey in 2014 among 500 people from the target population in the Netherlands. We enquired about their intention to take an expanded PCS test if one was offered, and through which provider they would like to see it offered. One-third of the respondents said they would take such a test were it to be offered. The majority (44%) preferred the test to be offered via their general practitioner (GP) and 58% would be willing to pay for the test, with a median cost of €75. Our next step is to perform an implementation study in which this PCS test will be provided via selected GPs in the Northern Netherlands. PMID:27165008

  9. Urinary levels of bisphenol A, triclosan and 4-nonylphenol in a general Belgian population.

    PubMed

    Pirard, Catherine; Sagot, Clémence; Deville, Marine; Dubois, Nathalie; Charlier, Corinne

    2012-11-01

    Bisphenol A, triclosan and 4-nonylphenol are among the endocrine disruptors which are widely used in daily products. In this study, we reported total urinary levels of bisphenol A, triclosan and 4-nonylphenol, in order to evaluate the baseline contamination of a general population in Belgium. Bisphenol A and triclosan were detected in respectively 97.7% and 74.6% of the samples examined demonstrating that the general Belgian population is extensively exposed to both chemicals. On the other hand, 4-nonylphenol was not detected in any urine samples analyzed, suggesting either low exposure, inadequate biomarker, or that urine is an inappropriate biological matrix for assessing exposure to nonylphenol commercial mixtures. Geometric mean concentration was determined for bisphenol A at 2.55 μg/l and for triclosan at 2.70 μg/l. No significant difference was observed between levels and gender for both bisphenol A and triclosan. When classified by age, the 20-39 year group showed the highest triclosan levels, while all age groups seemed to be similarly exposed to bisphenol A. Both bisphenol A and triclosan urinary levels were not correlated with creatinine excretion in our healthy population, questioning the relevance of the creatinine adjustment in reporting these chemical levels. Bisphenol A levels in urine of people living in the same home and collected on the same time were fairly correlated, confirming the assumption that dietary intake would be the primary route of exposure. Triclosan urinary levels were not correlated with bisphenol A levels.

  10. Plasma vitamins A, C and E in the general population of Singapore, 1993 to 1995.

    PubMed

    Hughes, K; New, A L; Lee, B L; Ong, C N

    1998-03-01

    The National University of Singapore Heart Study measured cardiovascular risk factors, including selected plasma vitamins, on a random sample of the general population aged 30 to 69 years. Plasma vitamins A and E were normal and similar by ethnic group. Mean plasma vitamin A levels were: Chinese (males 0.68 and females 0.52 mg/L), Malays (males 0.67 and females 0.54 mg/L), and Indians (males 0.66 and females 0.51 mg/L). Mean plasma vitamin E levels were: Chinese (males 12.6 and females 12.6 mg/L), Malays (males 13.6 and females 13.3 mg/L), and Indians (males 12.9 and females 12.8 mg/L). No person had plasma vitamin A deficiency (< 0.01 mg/L) and only 0.1% had vitamin E deficiency (< 5.0 mg/L). In contrast, plasma vitamin C was on the low side and higher in Chinese than Malays and Indians. Mean plasma vitamin C levels were: Chinese (males 6.3 and females 8.4 mg/L), Malays (males 5.1 and females 6.4 mg/L), and Indians (males 5.7 and females 6.9 mg/L). Likewise, the proportions with plasma vitamin C deficiency (< 2.0 mg/L) were lower in Chinese (males 14.4 and females 0.7%), than Malays (males 19.7 and females 7.2%), and Indians (males 17.8 and females 11.0%). Relatively low levels of plasma vitamin C may contribute to the high rates of coronary heart disease and cancer in Singapore. In particular, lower plasma vitamin C in Malays and Indians than Chinese may contribute to their higher rates of coronary heart disease. However, plasma vitamin C does not seem to be involved in the higher rates of cancer in Chinese than Malays and Indians. The findings suggest a relatively low intake of fresh fruits and a higher intake is recommended. Also, food sources of vitamin C may be destroyed by the high cooking temperatures of local cuisines, especially the Malay and Indian ones. PMID:9663300

  11. Metabolome in schizophrenia and other psychotic disorders: a general population-based study

    PubMed Central

    2011-01-01

    Background Persons with schizophrenia and other psychotic disorders have a high prevalence of obesity, impaired glucose tolerance, and lipid abnormalities, particularly hypertriglyceridemia and low high-density lipoprotein. More detailed molecular information on the metabolic abnormalities may reveal clues about the pathophysiology of these changes, as well as about disease specificity. Methods We applied comprehensive metabolomics in serum samples from a general population-based study in Finland. The study included all persons with DSM-IV primary psychotic disorder (schizophrenia, n = 45; other non-affective psychosis (ONAP), n = 57; affective psychosis, n = 37) and controls matched by age, sex, and region of residence. Two analytical platforms for metabolomics were applied to all serum samples: a global lipidomics platform based on ultra-performance liquid chromatography coupled to mass spectrometry, which covers molecular lipids such as phospholipids and neutral lipids; and a platform for small polar metabolites based on two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC × GC-TOFMS). Results Compared with their matched controls, persons with schizophrenia had significantly higher metabolite levels in six lipid clusters containing mainly saturated triglycerides, and in two small-molecule clusters containing, among other metabolites, (1) branched chain amino acids, phenylalanine and tyrosine, and (2) proline, glutamic, lactic and pyruvic acids. Among these, serum glutamic acid was elevated in all psychoses (P = 0.0020) compared to controls, while proline upregulation (P = 0.000023) was specific to schizophrenia. After adjusting for medication and metabolic comorbidity in linear mixed models, schizophrenia remained independently associated with higher levels in seven of these eight clusters (P < 0.05 in each cluster). The metabolic abnormalities were less pronounced in persons with ONAP or affective psychosis. Conclusions Our

  12. Endoscopic retrograde cholangiopancreatography-related adverse events: general overview.

    PubMed

    Rustagi, Tarun; Jamidar, Priya A

    2015-01-01

    Endoscopic retrograde cholangiopancreatography (ERCP) represents a monumental advance in the management of patients with pancreaticobiliary diseases, but is a complex and technically demanding procedure with the highest inherent risk of adverse events of all routine endoscopic procedures. Overall adverse event rates for ERCP are typically reported as 5-10%. The most commonly reported adverse events include post-ERCP pancreatitis, bleeding, perforation, infection (cholangitis), and cardiopulomary or "sedation related" events. This article evaluates patient-related and procedure-related risk factors for ERCP-related adverse events, and discusses strategies for the prevention, diagnosis and management of these events.

  13. Testing for Ancient Admixture between Closely Related Populations

    PubMed Central

    Durand, Eric Y.; Patterson, Nick; Reich, David; Slatkin, Montgomery

    2011-01-01

    One enduring question in evolutionary biology is the extent of archaic admixture in the genomes of present-day populations. In this paper, we present a test for ancient admixture that exploits the asymmetry in the frequencies of the two nonconcordant gene trees in a three-population tree. This test was first applied to detect interbreeding between Neandertals and modern humans. We derive the analytic expectation of a test statistic, called the D statistic, which is sensitive to asymmetry under alternative demographic scenarios. We show that the D statistic is insensitive to some demographic assumptions such as ancestral population sizes and requires only the assumption that the ancestral populations were randomly mating. An important aspect of D statistics is that they can be used to detect archaic admixture even when no archaic sample is available. We explore the effect of sequencing error on the false-positive rate of the test for admixture, and we show how to estimate the proportion of archaic ancestry in the genomes of present-day populations. We also investigate a model of subdivision in ancestral populations that can result in D statistics that indicate recent admixture. PMID:21325092

  14. German Anxiety Barometer—Clinical and Everyday-Life Anxieties in the General Population

    PubMed Central

    Adolph, Dirk; Schneider, Silvia; Margraf, Jürgen

    2016-01-01

    The objective of this study was to test a time-efficient screening instrument to assess clinically relevant and everyday-life (e.g., economic, political, personal) anxieties. Furthermore, factors influencing these anxieties, correlations between clinical and everyday anxieties and, for the first time, anxiety during different stages of life were assessed in a representative sample of the general population (N = 2229). Around 30% of the respondents manifested at least one disorder-specific key symptom within 1 year (women > men), 8% reported severe anxiety symptoms. Two thirds of respondents reported minor everyday anxieties and 5% were strongly impaired, whereby persons with severe clinical symptoms were more frequently affected. A variety of potential influencing factors could be identified. These include, in addition to socioeconomic status, gender, general health, risk-taking, and leisure behavior, also some up to now little investigated possible protective factors, such as everyday-life mental activity. The observed effects are rather small, which, however, given the heterogeneity of the general population seems plausible. Although the correlative design of the study does not allow direct causal conclusions, it can, however, serve as a starting point for experimental intervention studies in the future. Together with time series from repeated representative surveys, we expect these data to provide a better understanding of the processes that underlie everyday-life and clinical anxieties. PMID:27667977

  15. The Epidemiology of Major Depressive Episode in the Iraqi General Population

    PubMed Central

    Al-Hamzawi, Ali Obaid; Bruffaerts, Ronny; Bromet, Evelyn J.; AlKhafaji, Abdulzahra Mohammed; Kessler, Ronald C.

    2015-01-01

    Objective To assess the prevalence, symptom severity, functional impairment, and treatment of major depressive episode (MDE) in the Iraqi general population. Methods The Iraq Mental Health Survey is a nationally representative face-to-face survey of 4,332 non-institutionalized adults aged 18+ interviewed in 2006–2007 as part of the WHO World Mental Health Surveys. Prevalence and correlates of DSM-IV MDE were determined with the WHO Composite International Diagnostic Interview (CIDI). Findings Lifetime and 12-month prevalence of MDE were 7.4% and 4.0%, respectively. Close to half (46%) of the 12-month MDE cases were severe/very severe. MDE was more common among women and those previously married. Median age of onset was 25.2. Only one-seventh of 12-month MDE cases received treatment despite being associated with very substantial role impairment (on average 70 days out of role in the past year). Conclusions MDE is a commonly occurring disorder in the Iraqi general population and is associated with considerable disability and low treatment. Efforts are needed to decrease the barriers to treatment and to educate general medical providers in Iraq about the recognition and treatment of depression. PMID:26230265

  16. German Anxiety Barometer—Clinical and Everyday-Life Anxieties in the General Population

    PubMed Central

    Adolph, Dirk; Schneider, Silvia; Margraf, Jürgen

    2016-01-01

    The objective of this study was to test a time-efficient screening instrument to assess clinically relevant and everyday-life (e.g., economic, political, personal) anxieties. Furthermore, factors influencing these anxieties, correlations between clinical and everyday anxieties and, for the first time, anxiety during different stages of life were assessed in a representative sample of the general population (N = 2229). Around 30% of the respondents manifested at least one disorder-specific key symptom within 1 year (women > men), 8% reported severe anxiety symptoms. Two thirds of respondents reported minor everyday anxieties and 5% were strongly impaired, whereby persons with severe clinical symptoms were more frequently affected. A variety of potential influencing factors could be identified. These include, in addition to socioeconomic status, gender, general health, risk-taking, and leisure behavior, also some up to now little investigated possible protective factors, such as everyday-life mental activity. The observed effects are rather small, which, however, given the heterogeneity of the general population seems plausible. Although the correlative design of the study does not allow direct causal conclusions, it can, however, serve as a starting point for experimental intervention studies in the future. Together with time series from repeated representative surveys, we expect these data to provide a better understanding of the processes that underlie everyday-life and clinical anxieties.

  17. Incidence of symptomatic femoroacetabular impingement in the general population: a prospective registration study

    PubMed Central

    Röling, Maarten A.; Mathijssen, Nina M.C.; Bloem, Rolf M.

    2016-01-01

    Groin pain is a frequent cause of discomfort in patients and highly prevalent in active patients. One of the diagnoses causing groin pain is femoroacetabular impingement (FAI). However, the incidence of FAI in the general population is unknown. This study aimed to identify the incidence of groin pain suggestive of FAI in a cohort of 31 451 patients in the Netherlands during 1 year. A cooperation of 16 general practitioners (GPs) participated in this prospective registry. All GPs were educated in the clinical manifestation of FAI and the physical examination for FAI. Patients of all ages were registered when presenting with ‘groin pain’. Between July 2013 and July 2014, 84 patients aged between 15 and 60 years of age presented with groin pain, reflecting an incidence of 0.44%. Of these patients, 17% (14 patients) were radiologically diagnosed with FAI. Another 30% of these patients had a high clinical suspicion for FAI. This is the first report on the incidence of groin pain suggestive of FAI in a general population diagnosed by GPs. Of all 84 patients presenting with groin pain, 17% were diagnosed with FAI. Creating awareness of FAI in GPs helps identifying patients that might benefit from FAI treatment. PMID:27583159

  18. Incidence of symptomatic femoroacetabular impingement in the general population: a prospective registration study.

    PubMed

    Röling, Maarten A; Mathijssen, Nina M C; Bloem, Rolf M

    2016-08-01

    Groin pain is a frequent cause of discomfort in patients and highly prevalent in active patients. One of the diagnoses causing groin pain is femoroacetabular impingement (FAI). However, the incidence of FAI in the general population is unknown. This study aimed to identify the incidence of groin pain suggestive of FAI in a cohort of 31 451 patients in the Netherlands during 1 year. A cooperation of 16 general practitioners (GPs) participated in this prospective registry. All GPs were educated in the clinical manifestation of FAI and the physical examination for FAI. Patients of all ages were registered when presenting with 'groin pain'. Between July 2013 and July 2014, 84 patients aged between 15 and 60 years of age presented with groin pain, reflecting an incidence of 0.44%. Of these patients, 17% (14 patients) were radiologically diagnosed with FAI. Another 30% of these patients had a high clinical suspicion for FAI. This is the first report on the incidence of groin pain suggestive of FAI in a general population diagnosed by GPs. Of all 84 patients presenting with groin pain, 17% were diagnosed with FAI. Creating awareness of FAI in GPs helps identifying patients that might benefit from FAI treatment. PMID:27583159

  19. German Anxiety Barometer-Clinical and Everyday-Life Anxieties in the General Population.

    PubMed

    Adolph, Dirk; Schneider, Silvia; Margraf, Jürgen

    2016-01-01

    The objective of this study was to test a time-efficient screening instrument to assess clinically relevant and everyday-life (e.g., economic, political, personal) anxieties. Furthermore, factors influencing these anxieties, correlations between clinical and everyday anxieties and, for the first time, anxiety during different stages of life were assessed in a representative sample of the general population (N = 2229). Around 30% of the respondents manifested at least one disorder-specific key symptom within 1 year (women > men), 8% reported severe anxiety symptoms. Two thirds of respondents reported minor everyday anxieties and 5% were strongly impaired, whereby persons with severe clinical symptoms were more frequently affected. A variety of potential influencing factors could be identified. These include, in addition to socioeconomic status, gender, general health, risk-taking, and leisure behavior, also some up to now little investigated possible protective factors, such as everyday-life mental activity. The observed effects are rather small, which, however, given the heterogeneity of the general population seems plausible. Although the correlative design of the study does not allow direct causal conclusions, it can, however, serve as a starting point for experimental intervention studies in the future. Together with time series from repeated representative surveys, we expect these data to provide a better understanding of the processes that underlie everyday-life and clinical anxieties. PMID:27667977

  20. GENERAL: Mutual Information and Relative Entropy of Sequential Effect Algebras

    NASA Astrophysics Data System (ADS)

    Wang, Jia-Mei; Wu, Jun-De; Cho, Minhyung

    2010-08-01

    In this paper, we introduce and investigate the mutual information and relative entropy on the sequential effect algebra, we also give a comparison of these mutual information and relative entropy with the classical ones by the venn diagrams. Finally, a nice example shows that the entropies of sequential effect algebra depend extremely on the order of its sequential product.

  1. Lactase persistence-related genetic variant: population substructure and health outcomes.

    PubMed

    Smith, George Davey; Lawlor, Debbie A; Timpson, Nic J; Baban, Jamil; Kiessling, Matt; Day, Ian N M; Ebrahim, Shah

    2009-03-01

    Lactase persistence is an autosomal-dominant trait that is common in European-derived populations. A basic tendency for lactase persistence to increase from the southeast to the northwest across European populations has been noted, but such trends within countries have not been extensively studied. We genotyped the C/T(-13910) variant (rs4988235) that constitutes the putatively causal allele for lactase persistence (T allele representing persistence) in a general population sample of 3344 women aged 60-79 years from 23 towns across Britain. We found an overall frequency of 0.253 for the C (lactase non-persistence) allele, but with considerable gradients of decreasing frequency from the south to the north and from the east to the west of Britain for this allele. Daily sunlight was positively related to C (non-persistence) allele prevalence. However, sunlight exposure and latitude are strongly correlated, and it was not possible to identify which is the primary factor statistically underlying the distribution of lactase persistence. The C/T(-13910) variant (rs4988235) was not related to drinking milk or bone health (although drinking milk itself was protective of bone health), and was essentially unrelated to a wide range of other lifestyle, health and demographic characteristics. One exception was general health being rated as being poor or fair, for which there was an odds ratio of 1.38 (1.04, 1.84) for women homozygous for the C allele; on adjustment for latitude and longitude of place of birth, this attenuated to 1.19 (0.87, 1.64). The lactase persistence variant could contribute to the examination of data for the existence of, and then statistical control for, population substructure in genetic association studies.

  2. Momentum in general relativity: local versus quasilocal conservation laws

    NASA Astrophysics Data System (ADS)

    Epp, Richard J.; McGrath, Paul L.; Mann, Robert B.

    2013-10-01

    We construct a general relativistic conservation law for linear and angular momentum for matter and gravitational fields in a finite volume of space that does not rely on any spacetime symmetries. This work builds on our previous construction of a general relativistic energy conservation law with the same features (McGrath et al 2012 Class. Quantum Grav. 29 215012). Our approach uses the Brown and York (1993 Phys. Rev. D 47 1407-19) quasilocal stress-energy-momentum tensor for matter and gravitational fields, plus the concept of a rigid quasilocal frame (RQF) introduced in (Epp et al 2009 Class. Quantum Grav. 26 035015; 2012 Classical and Quantum Gravity: Theory, Analysis, and Applications (Nova Science)). The RQF approach allows us to construct, in a generic spacetime, frames of reference whose boundaries are rigid (their shape and size do not change with time), and that have precisely the same six arbitrary time-dependent degrees of freedom as the accelerating and tumbling rigid frames we are familiar with in Newtonian mechanics. These RQFs, in turn, give rise to a completely general conservation law for the six components of momentum (three linear and three angular) of a finite system of matter and gravitational fields. We compare in detail this quasilocal RQF approach to constructing conservation laws with the usual local one based on spacetime symmetries, and discuss the shortcomings of the latter. These RQF conservation laws lead to a deeper understanding of physics in the form of simple, exact, operational definitions of gravitational energy and momentum fluxes, which in turn reveal, for the first time, the exact, detailed mechanisms of gravitational energy and momentum transfer taking place in a wide variety of physical phenomena, including a simple falling apple. As a concrete example, we derive a general relativistic version of Archimedes’ law that we apply to understand electrostatic weight and buoyant force in the context of a Reissner

  3. How overdetermined are the generalized self-duality relations?

    NASA Astrophysics Data System (ADS)

    Tchrakian, D. H.; Chakrabarti, A.

    1991-09-01

    It is shown that the self-duality equations of the generalized Yang-Mills (GYM) models are overdetermined except when they are subjected to the spherical or axial symmetry. It is also found that the Bogomol'nyi equations on Rd, of the GYM-Higgs (GYM-H) models descended from the GYM system on Rd×S8-d, are overdetermined for d=3,4,5, and 6 only.

  4. [Anxiety and depression in the general population: normal values in the Hospital Anxiety and Depression Scale].

    PubMed

    Hinz, A; Schwarz, R

    2001-05-01

    For the Hospital Anxiety and Depression Scale (HADS) psychometric properties were tested and standardised values were calculated on the basis of a representative sample of the German adult population with 2037 persons. The main result was the evidence of age and gender differences for anxiety and depression. Females were more anxious than males. For both dimensions of the HADS a nearly linear age dependency was found which was more pronounced for depression (r = 0.36) than for anxiety (r = 0.14). Standardised values are given for different age and gender groups, and the results of regression analyses are presented. The psychometric properties were satisfying or good, the two-dimensional factorial structure could be replicated. By means of the standardised values and regression coefficients it is now possible to compare patient groups of different age and gender distributions with the general population. PMID:11417357

  5. Urinary excretion and daily intake rates of diethyl phthalate in the general Canadian population.

    PubMed

    Saravanabhavan, Gurusankar; Walker, Mike; Guay, Mireille; Aylward, Lesa

    2014-12-01

    We have analyzed the trends in the body-weight-adjusted urinary monoethyl phthalate (MEP) concentrations and the diethyl ethyl phthalate (DEP) daily intake estimates in the general Canadian population (aged 6-49 years) using the Canadian Health Measures Survey 2007-2009 dataset. The creatinine correction approach, as well as the urine volume approach in a simple one compartment model were used to calculate the daily urinary MEP excretion rates and DEP intake rates in individual survey participants. Using multiple regression models, we have estimated least square geometric means (LSGMs) of body-weight-adjusted MEP concentration, daily excretion and intake rates among different age groups and sex. We observed that body weight affects the trends in the MEP concentrations significantly among children (aged 6-11 years), adolescents (aged 12-19 years) and adults (aged 20-49 years). The body-weight-adjusted MEP concentrations in children were significantly higher than those in adults. On the other hand the DEP daily intakes in children were significantly lower than those in adults. We did not observe any differences in the DEP daily intake rates between males and females. Although the urinary MEP concentrations are correlated well with DEP daily intake estimates in the overall population, one should be cautious when directly using the urinary concentrations to compare the intake trends in the sub-populations (e.g. children vs. adults) as these trends are governed by additional physiological factors. The DEP daily intake calculated using the creatinine approach and that using the urine volume approach were similar to each other. The estimated geometric mean and 95th percentile of DEP daily intake in the general Canadian population are 2 and 20 μg/kg-bw/day, respectively. These daily intake estimates are significantly lower than the US Environmental Protection Agency's oral reference dose of 800 μg/kg-bw/day. PMID:25217994

  6. Associations of carotid intima-media thickness, tobacco smoking and overweight with hearing disorder in a general population sample.

    PubMed

    John, U; Baumeister, S E; Kessler, C; Völzke, H

    2007-11-01

    It has been argued that smoking or overweight might contribute to hearing disorder by atherogenic narrowing of the nutrient arteries to the cochlea. The carotid intima-media thickness (CIMT) is a surrogate marker for generalized atherosclerosis. We analyzed a subgroup (n=2619) from a general population sample in north-eastern Germany aged 45-81 years (Study of Health in Pomerania, SHIP). Assessments included self-statements about hearing disorder and medical examinations of CIMT. Using ordinal logistic regression for data analysis and after adjustment for cigarettes per day, waist circumference, diabetes, exposure to noise, age and sex, we found CIMT remained a predictor of hearing disorder (odds ratio 1.8, 95% confidence interval 1.0-3.2). Cigarettes per day and waist circumference were related to CIMT but not to hearing disorder. The findings suggest a positive association between CIMT and hearing disorder.

  7. Are MAO-A deficiency states in the general population and in putative high-risk populations highly uncommon?

    PubMed

    Murphy, D L; Sims, K; Eisenhofer, G; Greenberg, B D; George, T; Berlin, F; Zametkin, A; Ernst, M; Breakefield, X O

    1998-01-01

    Lack of monoamine oxidase A (MAO-A) due to either Xp chromosomal deletions or alterations in the coding sequence of the gene for this enzyme are associated with marked changes in monoamine metabolism and appear to be associated with variable cognitive deficits and behavioral changes in humans and in transgenic mice. In mice, some of the most marked behavioral changes are ameliorated by pharmacologically-induced reductions in serotonin synthesis during early development, raising the question of possible therapeutic interventions in humans with MAO deficiency states. At the present time, only one multi-generational family and a few other individuals with marked MAO-A deficiency states have been identified and studied in detail. Although MAO deficiency states associated with Xp chromosomal deletions were identified by distinct symptoms (including blindness in infancy) produced by the contiguous Norrie disease gene, the primarily behavioral phenotype of individuals with the MAO mutation is less obvious. This paper reports a sequential research design and preliminary results from screening several hundred volunteers in the general population and from putative high-risk groups for possible MAO deficiency states. These preliminary results suggest that marked MAO deficiency states are very rare.

  8. Prediction models for cardiovascular disease risk in the general population: systematic review

    PubMed Central

    Hooft, Lotty; Schuit, Ewoud; Debray, Thomas P A; Collins, Gary S; Tzoulaki, Ioanna; Lassale, Camille M; Siontis, George C M; Chiocchia, Virginia; Roberts, Corran; Schlüssel, Michael Maia; Gerry, Stephen; Black, James A; Heus, Pauline; van der Schouw, Yvonne T; Peelen, Linda M; Moons, Karel G M

    2016-01-01

    Objective To provide an overview of prediction models for risk of cardiovascular disease (CVD) in the general population. Design Systematic review. Data sources Medline and Embase until June 2013. Eligibility criteria for study selection Studies describing the development or external validation of a multivariable model for predicting CVD risk in the general population. Results 9965 references were screened, of which 212 articles were included in the review, describing the development of 363 prediction models and 473 external validations. Most models were developed in Europe (n=167, 46%), predicted risk of fatal or non-fatal coronary heart disease (n=118, 33%) over a 10 year period (n=209, 58%). The most common predictors were smoking (n=325, 90%) and age (n=321, 88%), and most models were sex specific (n=250, 69%). Substantial heterogeneity in predictor and outcome definitions was observed between models, and important clinical and methodological information were often missing. The prediction horizon was not specified for 49 models (13%), and for 92 (25%) crucial information was missing to enable the model to be used for individual risk prediction. Only 132 developed models (36%) were externally validated and only 70 (19%) by independent investigators. Model performance was heterogeneous and measures such as discrimination and calibration were reported for only 65% and 58% of the external validations, respectively. Conclusions There is an excess of models predicting incident CVD in the general population. The usefulness of most of the models remains unclear owing to methodological shortcomings, incomplete presentation, and lack of external validation and model impact studies. Rather than developing yet another similar CVD risk prediction model, in this era of large datasets, future research should focus on externally validating and comparing head-to-head promising CVD risk models that already exist, on tailoring or even combining these models to local