Science.gov

Sample records for general purpose cellular

  1. General-purpose optimization methods for parallelization of digital terrain analysis based on cellular automata

    NASA Astrophysics Data System (ADS)

    Cheng, Guo; Liu, Lu; Jing, Ning; Chen, Luo; Xiong, Wei

    2012-08-01

    Solving traditional spatial analysis problems benefits from high performance geo-computation powered by parallel computing. Digital Terrain Analysis (DTA) is a typical example of data and computationally intensive spatial analysis problems and can be improved by parallelization technologies. Previous work on this topic has mainly focused on applying optimization schemes for specific DTA case studies. The task addressed in this paper, in contrast, is to find optimization methods that are generally applicable to the parallelization of DTA. By modeling a complex DTA problem with Cellular Automata (CA), we developed a temporal model that can describe the time cost of the solution. Three methods for optimizing different components in the temporal model are proposed: (1) a parallel loading/writing method that can improve the IO efficiency; (2) a best cell division method that can minimize the communication time among processes; and (3) a communication evolution overlapping method that can reduce the total time of evolutions and communications. The feasibilities and practical efficiencies of the proposed methods have been verified by comparative experiments conducted on an elevation dataset from North America using the Slope of Aspect (SOA) as an example of a general DTA problem. The results showed that the parallel performance of the SOA can be improved by applying the proposed methods individually or in an integrated fashion.

  2. A general purpose contouring system

    USGS Publications Warehouse

    Evenden, Gerald Ian

    1975-01-01

    Three Decsystem-10 FORTRAN IV programs provide a general purpose system for contouring two-dimensional data. The system can provide both quick or final, publication quality contour maps on either interactive or offline plotting devices. Complete user documentation, with examples, and program listings are presented.

  3. General purpose programmable accelerator board

    DOEpatents

    Robertson, Perry J.; Witzke, Edward L.

    2001-01-01

    A general purpose accelerator board and acceleration method comprising use of: one or more programmable logic devices; a plurality of memory blocks; bus interface for communicating data between the memory blocks and devices external to the board; and dynamic programming capabilities for providing logic to the programmable logic device to be executed on data in the memory blocks.

  4. General purpose steam table library :

    SciTech Connect

    Carpenter, John H.; Belcourt, Kenneth Noel; Nourgaliev, Robert

    2013-08-01

    Completion of the CASL L3 milestone THM.CFD.P7.04 provides a general purpose tabular interpolation library for material properties to support, in particular, standardized models for steam properties. The software consists of three parts, implementations of analytic steam models, a code to generate tables from those models, and an interpolation package to interface the tables to CFD codes such as Hydra-TH. Verification of the standard model is maintained through the entire train of routines. The performance of interpolation package exceeds that of freely available analytic implementation of the steam properties by over an order of magnitude.

  5. Cellular Automata Generalized To An Inferential System

    NASA Astrophysics Data System (ADS)

    Blower, David J.

    2007-11-01

    Stephen Wolfram popularized elementary one-dimensional cellular automata in his book, A New Kind of Science. Among many remarkable things, he proved that one of these cellular automata was a Universal Turing Machine. Such cellular automata can be interpreted in a different way by viewing them within the context of the formal manipulation rules from probability theory. Bayes's Theorem is the most famous of such formal rules. As a prelude, we recapitulate Jaynes's presentation of how probability theory generalizes classical logic using modus ponens as the canonical example. We emphasize the important conceptual standing of Boolean Algebra for the formal rules of probability manipulation and give an alternative demonstration augmenting and complementing Jaynes's derivation. We show the complementary roles played in arguments of this kind by Bayes's Theorem and joint probability tables. A good explanation for all of this is afforded by the expansion of any particular logic function via the disjunctive normal form (DNF). The DNF expansion is a useful heuristic emphasized in this exposition because such expansions point out where relevant 0s should be placed in the joint probability tables for logic functions involving any number of variables. It then becomes a straightforward exercise to rely on Boolean Algebra, Bayes's Theorem, and joint probability tables in extrapolating to Wolfram's cellular automata. Cellular automata are seen as purely deductive systems, just like classical logic, which probability theory is then able to generalize. Thus, any uncertainties which we might like to introduce into the discussion about cellular automata are handled with ease via the familiar inferential path. Most importantly, the difficult problem of predicting what cellular automata will do in the far future is treated like any inferential prediction problem.

  6. General purpose computers in real time

    SciTech Connect

    Biel, J.R.

    1989-09-18

    I see three main trends in the use of general purpose computers in real time. The first is more processing power. The second is the use of higher speed interconnects between computers (allowing more data to be delivered to the processors). The third is the use of larger programs running in the computers. Although there is still work that needs to be done, I believe that all indications are that the online need for general purpose computers should be available for the SCC and LHC machines. 2 figs.

  7. 7 CFR 254.1 - General purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... INDIAN HOUSEHOLDS IN OKLAHOMA § 254.1 General purpose. This part sets the requirement under which... service areas in Oklahoma. This part also sets the conditions for administration of the Food Distribution Program by eligible Oklahoma tribes determined capable by the Department....

  8. 7 CFR 254.1 - General purpose.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... INDIAN HOUSEHOLDS IN OKLAHOMA § 254.1 General purpose. This part sets the requirement under which... service areas in Oklahoma. This part also sets the conditions for administration of the Food Distribution Program by eligible Oklahoma tribes determined capable by the Department....

  9. Field Evaluation of a General Purpose Simulator.

    ERIC Educational Resources Information Center

    Spangenberg, Ronald W.

    The use of a general purpose simulator (GPS) to teach Air Force technicians diagnostic and repair procedures for specialized aircraft radar systems is described. An EC II simulator manufactured by Educational Computer Corporation was adapted to resemble the actual configuration technicians would encounter in the field. Data acquired in the…

  10. 10 CFR 205.350 - General purpose.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false General purpose. 205.350 Section 205.350 Energy DEPARTMENT OF ENERGY OIL ADMINISTRATIVE PROCEDURES AND SANCTIONS Electric Power System Permits and Reports... on the electric energy supply systems in the United States so that appropriate Federal...

  11. 10 CFR 205.350 - General purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false General purpose. 205.350 Section 205.350 Energy DEPARTMENT OF ENERGY OIL ADMINISTRATIVE PROCEDURES AND SANCTIONS Electric Power System Permits and Reports... on the electric energy supply systems in the United States so that appropriate Federal...

  12. General-Purpose Compression for Efficient Retrieval.

    ERIC Educational Resources Information Center

    Cannane, Adam; Williams, Hugh E.

    2001-01-01

    Discusses compression of databases that reduces space requirements and retrieval times; considers compression of documents in text databases based on semistatic modeling with words; and proposes a scheme for general purpose compression that can be applied to all types of data stored in large collections. (Author/LRW)

  13. 12 CFR 1703.31 - General purposes.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false General purposes. 1703.31 Section 1703.31 Banks... DEVELOPMENT OFHEO ORGANIZATION AND FUNCTIONS RELEASE OF INFORMATION Testimony and Production of Documents in... time of employees for their official duties, maintain the impartial position of OFHEO in litigation...

  14. General-Purpose Image-Data Program

    NASA Technical Reports Server (NTRS)

    Engle, Steven W.

    1988-01-01

    Image Database computer program, IBASE, is general-purpose imagery-information system. Use accomplished either by commands or through hierarchy of menus. Analytical capabilities of IBASE include contigency tables, image filtering (low-, high-, and band-pass), proximity maps, clustering, histograms, regression, slope calculations, scaling, and Boolean manipulations. Also has interface to Cheshire Image Classification expert system. Written in FORTRAN 77.

  15. PRISM: a general purpose programming system

    SciTech Connect

    Rogers, C.R.; O'Hara, S.A.

    1983-03-01

    This paper describes the development, uses, and features of the general purpose programming system PRISM, which is the foundation for future program development by the Computer Programming Branch and is available to all personnel within the Air Force Human Resources Laboratory (AFHRL). PRISM was designed to meet the need for an efficient and reliable programming tool that could be used like a high-order programming language but still provide the operating system interface and hardware controls of assembly language. It has special features that make it an especially powerful tool for new software development. These features were derived from an extensive analysis of coding sequences in existing library programs, interactions between library programs, and the identification of common programming procedures. PRISM was specifically designed for the development of general purpose programs by the Technical Services Division of AFHRL within the Computer Programming Branch; however, it is also an effective and efficient tool for applications programmers.

  16. General-Purpose Graphics-Library Program

    NASA Technical Reports Server (NTRS)

    Rogers, Joseph E.

    1993-01-01

    NASA Device Independent Graphics Library (NASADIG) computer program is general-purpose graphics-library program for use with many computer-based-engineering and management application programs. Software offers many features providing user with flexibility in creating graphics. Includes two- and three-dimensional plotting, splines and polynomial interpolation, area blanking control, multiple log/linear axes, legends and text control, curve-thickness control, and multiple text fonts. Written in ANSI FORTRAN 77.

  17. General purpose optimization software for engineering design

    NASA Technical Reports Server (NTRS)

    Vanderplaats, G. N.

    1990-01-01

    The author has developed several general purpose optimization programs over the past twenty years. The earlier programs were developed as research codes and served that purpose reasonably well. However, in taking the formal step from research to industrial application programs, several important lessons have been learned. Among these are the importance of clear documentation, immediate user support, and consistent maintenance. Most important has been the issue of providing software that gives a good, or at least acceptable, design at minimum computational cost. Here, the basic issues developing optimization software for industrial applications are outlined and issues of convergence rate, reliability, and relative minima are discussed. Considerable feedback has been received from users, and new software is being developed to respond to identified needs. The basic capabilities of this software are outlined. A major motivation for the development of commercial grade software is ease of use and flexibility, and these issues are discussed with reference to general multidisciplinary applications. It is concluded that design productivity can be significantly enhanced by the more widespread use of optimization as an everyday design tool.

  18. General-Purpose Software For Computer Graphics

    NASA Technical Reports Server (NTRS)

    Rogers, Joseph E.

    1992-01-01

    NASA Device Independent Graphics Library (NASADIG) is general-purpose computer-graphics package for computer-based engineering and management applications which gives opportunity to translate data into effective graphical displays for presentation. Features include two- and three-dimensional plotting, spline and polynomial interpolation, control of blanking of areas, multiple log and/or linear axes, control of legends and text, control of thicknesses of curves, and multiple text fonts. Included are subroutines for definition of areas and axes of plots; setup and display of text; blanking of areas; setup of style, interpolation, and plotting of lines; control of patterns and of shading of colors; control of legends, blocks of text, and characters; initialization of devices; and setting of mixed alphabets. Written in FORTRAN 77.

  19. Deictic primitives for general purpose navigation

    NASA Technical Reports Server (NTRS)

    Crismann, Jill D.

    1994-01-01

    A visually-based deictic primative used as an elementary command set for general purpose navigation was investigated. It was shown that a simple 'follow your eyes' scenario is sufficient for tracking a moving target. Limitations of velocity, acceleration, and modeling of the response of the mechanical systems were enforced. Realistic paths of the robots were produced during the simulation. Scientists could remotely command a planetary rover to go to a particular rock formation that may be interesting. Similarly an expert at plant maintenance could obtain diagnostic information remotely by using deictic primitives on a mobile are used in the deictic primitives, we could imagine that the exact same control software could be used for all of these applications.

  20. General-purpose abductive algorithm for interpretation

    NASA Astrophysics Data System (ADS)

    Fox, Richard K.; Hartigan, Julie

    1996-11-01

    Abduction, inference to the best explanation, is an information-processing task that is useful for solving interpretation problems such as diagnosis, medical test analysis, legal reasoning, theory evaluation, and perception. The task is a generative one in which an explanation comprising of domain hypotheses is assembled and used to account for given findings. The explanation is taken to be an interpretation as to why the findings have arisen within the given situation. Research in abduction has led to the development of a general-purpose computational strategy which has been demonstrated on all of the above types of problems. This abduction strategy can be performed in layers so that different types of knowledge can come together in deriving an explanation at different levels of description. Further, the abduction strategy is tractable and offers a very useful tradeoff between confidence in the explanation and completeness of the explanation. This paper will describe this computational strategy for abduction and demonstrate its usefulness towards perceptual problems by examining problem-solving systems in speech recognition and natural language understanding.

  1. The General-Purpose Heat Source Radioisotope Thermoelectric Generator: A Truly General-Purpose Space RTG

    NASA Astrophysics Data System (ADS)

    Bennett, Gary L.; Lombardo, James J.; Hemler, Richard J.; Silverman, Gil; Whitmore, C. W.; Amos, Wayne R.; Johnson, E. W.; Zocher, Roy W.; Hagan, James C.; Englehart, Richard W.

    2008-01-01

    The General-Purpose Heat Source Radioisotope Thermoelectric Generator (GPHS-RTG) was developed for the originally planned International Solar Polar Mission (ISPM). [ISPM would later, with the elimination of the NASA spacecraft, become the Ulysses mission.] At 300 We beginning-of-life (BOL) power, the GPHS-RTG was the most powerful RTG with the highest specific power (5.3 We/kg) of any space RTG. These improved performance attributes of the GPHS-RTG made it attractive for use on the Galileo mission. Subsequently, the GPHS-RTG was selected to power the Cassini spacecraft, which is currently orbiting Saturn, and the New Horizons spacecraft which is on its way to Pluto. Truly, the GPHS-RTG is a ``general-purpose'' space RTG.

  2. 21 CFR 880.6890 - General purpose disinfectants.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false General purpose disinfectants. 880.6890 Section... Miscellaneous Devices § 880.6890 General purpose disinfectants. (a) Identification. A general purpose disinfectant is a germicide intended to process noncritical medical devices and equipment surfaces. A...

  3. 21 CFR 880.6890 - General purpose disinfectants.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false General purpose disinfectants. 880.6890 Section... Miscellaneous Devices § 880.6890 General purpose disinfectants. (a) Identification. A general purpose disinfectant is a germicide intended to process noncritical medical devices and equipment surfaces. A...

  4. 21 CFR 880.6890 - General purpose disinfectants.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false General purpose disinfectants. 880.6890 Section... Miscellaneous Devices § 880.6890 General purpose disinfectants. (a) Identification. A general purpose disinfectant is a germicide intended to process noncritical medical devices and equipment surfaces. A...

  5. 21 CFR 880.6890 - General purpose disinfectants.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false General purpose disinfectants. 880.6890 Section... Miscellaneous Devices § 880.6890 General purpose disinfectants. (a) Identification. A general purpose disinfectant is a germicide intended to process noncritical medical devices and equipment surfaces. A...

  6. 21 CFR 880.6890 - General purpose disinfectants.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false General purpose disinfectants. 880.6890 Section... Miscellaneous Devices § 880.6890 General purpose disinfectants. (a) Identification. A general purpose disinfectant is a germicide intended to process noncritical medical devices and equipment surfaces. A...

  7. 47 CFR 32.6124 - General purpose computers expense.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 2 2012-10-01 2012-10-01 false General purpose computers expense. 32.6124... General purpose computers expense. This account shall include the costs of personnel whose principal job is the physical operation of general purpose computers and the maintenance of operating systems....

  8. 47 CFR 32.6124 - General purpose computers expense.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false General purpose computers expense. 32.6124... General purpose computers expense. This account shall include the costs of personnel whose principal job is the physical operation of general purpose computers and the maintenance of operating systems....

  9. 47 CFR 32.6124 - General purpose computers expense.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false General purpose computers expense. 32.6124... General purpose computers expense. This account shall include the costs of personnel whose principal job is the physical operation of general purpose computers and the maintenance of operating systems....

  10. 47 CFR 32.6124 - General purpose computers expense.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 2 2014-10-01 2014-10-01 false General purpose computers expense. 32.6124... General purpose computers expense. This account shall include the costs of personnel whose principal job is the physical operation of general purpose computers and the maintenance of operating systems....

  11. 47 CFR 32.6124 - General purpose computers expense.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 2 2013-10-01 2013-10-01 false General purpose computers expense. 32.6124... General purpose computers expense. This account shall include the costs of personnel whose principal job is the physical operation of general purpose computers and the maintenance of operating systems....

  12. General English Ability, Specific Purpose English Ability, and Computer Skills.

    ERIC Educational Resources Information Center

    Prapphal, Kanchana

    2003-01-01

    Aims to answer the following research questions: (1) Are general English ability and specific purpose English ability related to computer skills? and (2) Is general English ability transferable to specific purpose English ability? Subjects were third year science students enrolled in an English for academic purposes course. (Author/VWL)

  13. 24 CFR 902.1 - Purpose, scope, and general matters.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... URBAN DEVELOPMENT PUBLIC HOUSING ASSESSMENT SYSTEM General Provisions § 902.1 Purpose, scope, and general matters. (a) Purpose. The purpose of the Public Housing Assessment System (PHAS) is to improve the delivery of services in public housing and enhance trust in the public housing system among public...

  14. 24 CFR 902.1 - Purpose, scope, and general matters.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... URBAN DEVELOPMENT PUBLIC HOUSING ASSESSMENT SYSTEM General Provisions § 902.1 Purpose, scope, and general matters. (a) Purpose. The purpose of the Public Housing Assessment System (PHAS) is to improve the delivery of services in public housing and enhance trust in the public housing system among public...

  15. 24 CFR 902.1 - Purpose, scope, and general matters.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... URBAN DEVELOPMENT PUBLIC HOUSING ASSESSMENT SYSTEM General Provisions § 902.1 Purpose, scope, and general matters. (a) Purpose. The purpose of the Public Housing Assessment System (PHAS) is to improve the delivery of services in public housing and enhance trust in the public housing system among public...

  16. 24 CFR 902.1 - Purpose, scope, and general matters.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... URBAN DEVELOPMENT PUBLIC HOUSING ASSESSMENT SYSTEM General Provisions § 902.1 Purpose, scope, and general matters. (a) Purpose. The purpose of the Public Housing Assessment System (PHAS) is to improve the delivery of services in public housing and enhance trust in the public housing system among public...

  17. 7 CFR 271.1 - General purpose and scope.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... purpose and scope. (a) Purpose of SNAP. SNAP is designed to promote the general welfare and to safeguard... guidelines for monitoring SNAP, analyzing the results and formulating corrective action. Part 276...

  18. 7 CFR 227.1 - General purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS NUTRITION EDUCATION AND TRAINING PROGRAM General § 227.1 General purpose and scope. The purpose of these regulations is to implement section 19 of the Child Nutrition...

  19. 7 CFR 227.1 - General purpose and scope.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS NUTRITION EDUCATION AND TRAINING PROGRAM General § 227.1 General purpose and scope. The purpose of these regulations is to implement section 19 of the Child Nutrition...

  20. 22 CFR 211.1 - General purpose and scope; legislation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false General purpose and scope; legislation. 211.1 Section 211.1 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT TRANSFER OF FOOD COMMODITIES FOR FOOD USE IN DISASTER RELIEF, ECONOMIC DEVELOPMENT AND OTHER ASSISTANCE § 211.1 General purpose and...

  1. 47 CFR 32.2124 - General purpose computers.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 2 2012-10-01 2012-10-01 false General purpose computers. 32.2124 Section 32... General purpose computers. (a) This account shall include the original cost of computers and peripheral... cost of computers and their associated peripheral devices associated with switching, network...

  2. 47 CFR 32.2124 - General purpose computers.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 2 2013-10-01 2013-10-01 false General purpose computers. 32.2124 Section 32... General purpose computers. (a) This account shall include the original cost of computers and peripheral... cost of computers and their associated peripheral devices associated with switching, network...

  3. 47 CFR 32.2124 - General purpose computers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false General purpose computers. 32.2124 Section 32... General purpose computers. (a) This account shall include the original cost of computers and peripheral... cost of computers and their associated peripheral devices associated with switching, network...

  4. 47 CFR 32.2124 - General purpose computers.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 2 2014-10-01 2014-10-01 false General purpose computers. 32.2124 Section 32... General purpose computers. (a) This account shall include the original cost of computers and peripheral... cost of computers and their associated peripheral devices associated with switching, network...

  5. 7 CFR 227.1 - General purpose and scope.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS NUTRITION EDUCATION AND TRAINING PROGRAM General § 227.1 General purpose and scope. The purpose of these regulations is to implement section 19 of the Child Nutrition...

  6. 7 CFR 227.1 - General purpose and scope.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS NUTRITION EDUCATION AND TRAINING PROGRAM General § 227.1 General purpose and scope. The purpose of these regulations is to implement section 19 of the Child Nutrition...

  7. 7 CFR 227.1 - General purpose and scope.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS NUTRITION EDUCATION AND TRAINING PROGRAM General § 227.1 General purpose and scope. The purpose of these regulations is to implement section 19 of the Child Nutrition...

  8. 7 CFR 210.1 - General purpose and scope.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS NATIONAL SCHOOL LUNCH PROGRAM General § 210.1 General purpose and scope. (a) Purpose of the program. Section 2 of the National School Lunch Act (42 U.S.C. 1751), states:...

  9. 7 CFR 210.1 - General purpose and scope.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AGRICULTURE CHILD NUTRITION PROGRAMS NATIONAL SCHOOL LUNCH PROGRAM General § 210.1 General purpose and scope. (a) Purpose of the program. Section 2 of the National School Lunch Act (42 U.S.C. 1751), states: “It... expansion of nonprofit school lunch programs.” Pursuant to this act, the Department provides States...

  10. 7 CFR 210.1 - General purpose and scope.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AGRICULTURE CHILD NUTRITION PROGRAMS NATIONAL SCHOOL LUNCH PROGRAM General § 210.1 General purpose and scope. (a) Purpose of the program. Section 2 of the National School Lunch Act (42 U.S.C. 1751), states: “It... expansion of nonprofit school lunch programs.” Pursuant to this act, the Department provides States...

  11. 7 CFR 210.1 - General purpose and scope.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AGRICULTURE CHILD NUTRITION PROGRAMS NATIONAL SCHOOL LUNCH PROGRAM General § 210.1 General purpose and scope. (a) Purpose of the program. Section 2 of the National School Lunch Act (42 U.S.C. 1751), states: “It... expansion of nonprofit school lunch programs.” Pursuant to this act, the Department provides States...

  12. GRASP: General-purpose Relativistic Atomic Structure Package

    NASA Astrophysics Data System (ADS)

    Grant, I. P.; McKenzie, B. J.; Norrington, P. H.; Mayers, D. F.; Pyper, N. C.

    2016-09-01

    GRASP (General-purpose Relativistic Atomic Structure Package) calculates atomic structure, including energy levels, radiative rates (A-values) and lifetimes; it is a fully relativistic code based on the jj coupling scheme.

  13. 7 CFR 220.1 - General purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AGRICULTURE CHILD NUTRITION PROGRAMS SCHOOL BREAKFAST PROGRAM § 220.1 General purpose and scope. This part announces the policies and prescribes the regulations necessary to carry out the provisions of section 4...

  14. 7 CFR 249.1 - General purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) General § 249.1 General... carry out the Senior Farmers' Market Nutrition Program (SFMNP). The purposes of the SFMNP are to:...

  15. 7 CFR 248.1 - General purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.1 General... out the WIC Farmers' Market Nutrition Program. The dual purposes of the FMNP are: (a) To...

  16. 7 CFR 248.1 - General purpose and scope.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.1 General... out the WIC Farmers' Market Nutrition Program. The dual purposes of the FMNP are: (a) To...

  17. 7 CFR 249.1 - General purpose and scope.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) General § 249.1 General... carry out the Senior Farmers' Market Nutrition Program (SFMNP). The purposes of the SFMNP are to:...

  18. 7 CFR 226.1 - General purpose and scope.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS CHILD AND ADULT CARE FOOD PROGRAM General § 226.1 General purpose and... Child and Adult Care Food Program. Section 17 of the National School Lunch Act, as amended,...

  19. 7 CFR 248.1 - General purpose and scope.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.1 General... out the WIC Farmers' Market Nutrition Program. The dual purposes of the FMNP are: (a) To...

  20. 7 CFR 248.1 - General purpose and scope.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.1 General... out the WIC Farmers' Market Nutrition Program. The dual purposes of the FMNP are: (a) To...

  1. 7 CFR 248.1 - General purpose and scope.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.1 General... out the WIC Farmers' Market Nutrition Program. The dual purposes of the FMNP are: (a) To...

  2. 7 CFR 226.1 - General purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS CHILD AND ADULT CARE FOOD PROGRAM General § 226.1 General purpose and... Child and Adult Care Food Program. Section 17 of the National School Lunch Act, as amended,...

  3. 7 CFR 225.1 - General purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SUMMER FOOD SERVICE PROGRAM General § 225.1 General purpose and scope. This part establishes the regulations under which the Secretary will administer a Summer Food...

  4. 7 CFR 226.1 - General purpose and scope.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Child and Adult Care Food Program. Section 17 of the National School Lunch Act, as amended, authorizes... AGRICULTURE CHILD NUTRITION PROGRAMS CHILD AND ADULT CARE FOOD PROGRAM General § 226.1 General purpose and... service programs for children or adult participants in nonresidential institutions which provide care....

  5. 7 CFR 226.1 - General purpose and scope.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Child and Adult Care Food Program. Section 17 of the National School Lunch Act, as amended, authorizes... AGRICULTURE CHILD NUTRITION PROGRAMS CHILD AND ADULT CARE FOOD PROGRAM General § 226.1 General purpose and... service programs for children or adult participants in nonresidential institutions which provide care....

  6. 7 CFR 226.1 - General purpose and scope.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Child and Adult Care Food Program. Section 17 of the National School Lunch Act, as amended, authorizes... AGRICULTURE CHILD NUTRITION PROGRAMS CHILD AND ADULT CARE FOOD PROGRAM General § 226.1 General purpose and... service programs for children or adult participants in nonresidential institutions which provide care....

  7. Special or general-purpose hardware for Prolog: A comparison

    SciTech Connect

    Borriello, G.; Cherenson, A.; Danzig, P.; Nelson, M.

    1987-01-01

    This study compares the performance of executing Prolog code on the Berkeley PLM processor (a special-purpose CISC architecture) and the Berkeley SPUR processor (a general-purpose RISC architecture with tagged data). Fourteen standard benchmark programs were run on both the PLM and SPUR simulators. The two implementations were compared with regard to static and dynamic program size, execution speed, and cache performance. The simulated memory system included a direct-mapped mixed instruction and data cache.

  8. 7 CFR 1485.10 - General purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... develop, maintain or expand commercial export markets for U.S. agricultural commodities and products. MAP... FOREIGN MARKETS FOR AGRICULTURAL COMMODITIES Market Access Program § 1485.10 General purpose and scope. (a... the Market Access Program (MAP), and a subcomponent of that program, the Export Incentive...

  9. 29 CFR 1960.66 - Purpose, scope and general provisions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., DEPARTMENT OF LABOR (CONTINUED) BASIC PROGRAM ELEMENTS FOR FEDERAL EMPLOYEE OCCUPATIONAL SAFETY AND HEALTH PROGRAMS AND RELATED MATTERS Recordkeeping and Reporting Requirements § 1960.66 Purpose, scope and general..., Federal agencies must have recording and reporting requirements that are the same as 29 CFR Part 1904...

  10. 29 CFR 1960.66 - Purpose, scope and general provisions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., DEPARTMENT OF LABOR (CONTINUED) BASIC PROGRAM ELEMENTS FOR FEDERAL EMPLOYEE OCCUPATIONAL SAFETY AND HEALTH PROGRAMS AND RELATED MATTERS Recordkeeping and Reporting Requirements § 1960.66 Purpose, scope and general..., Federal agencies must have recording and reporting requirements that are the same as 29 CFR Part 1904...

  11. 7 CFR 240.1 - General purpose and scope.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... nonresidential child or adult care institutions participating in the Child and Adult Care Food Program (7 CFR... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS CASH IN LIEU OF DONATED FOODS § 240.1 General purpose and scope. (a)...

  12. 7 CFR 235.1 - General purpose and scope.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... part 220), the Child and Adult Care Food Program (7 CFR part 226) and the Food Distribution Program (7... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS STATE ADMINISTRATIVE EXPENSE FUNDS § 235.1 General purpose and...

  13. 7 CFR 281.1 - General purpose and scope.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM ADMINISTRATION OF SNAP ON INDIAN RESERVATIONS § 281.1 General purpose and scope. (a) These regulations govern the operation of SNAP on Indian reservations either separately or concurrently with the Food distribution program. In order to assure that SNAP...

  14. 42 CFR 456.241 - Purpose and general description.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Purpose and general description. 456.241 Section 456.241 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Utilization Control: Mental...

  15. 42 CFR 456.241 - Purpose and general description.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Purpose and general description. 456.241 Section 456.241 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Utilization Control: Mental...

  16. 42 CFR 456.241 - Purpose and general description.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Purpose and general description. 456.241 Section 456.241 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Utilization Control: Mental...

  17. 42 CFR 456.241 - Purpose and general description.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Purpose and general description. 456.241 Section 456.241 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Utilization Control: Mental...

  18. 46 CFR 560.1 - Purpose; general provisions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 9 2013-10-01 2013-10-01 false Purpose; general provisions. 560.1 Section 560.1 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AND ACTIONS TO ADDRESS RESTRICTIVE FOREIGN MARITIME... the United States whether liner, bulk, tramp or other vessel, (hereinafter “U.S. flag vessel”)...

  19. 46 CFR 560.1 - Purpose; general provisions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 9 2012-10-01 2012-10-01 false Purpose; general provisions. 560.1 Section 560.1 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AND ACTIONS TO ADDRESS RESTRICTIVE FOREIGN MARITIME... the United States whether liner, bulk, tramp or other vessel, (hereinafter “U.S. flag vessel”)...

  20. 46 CFR 560.1 - Purpose; general provisions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Purpose; general provisions. 560.1 Section 560.1 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AND ACTIONS TO ADDRESS RESTRICTIVE FOREIGN MARITIME... the United States whether liner, bulk, tramp or other vessel, (hereinafter “U.S. flag vessel”)...

  1. Thermoplastic analysis of general-purpose heat-source modules

    NASA Astrophysics Data System (ADS)

    Chang, Y.; Ecker, J. A.

    1993-01-01

    Prior thermoelastic analyses were conducted to assess the thermostructural response of the Galileo radioisotope thermoelectric generators general-purpose heat-source (GPHS) modules upon possible accidental reentry into earth's atmosphere. These analyses are extended through the inclusion of thermoplasticity of the composite material of the GPHS modules. The thermoplastic analysis methods for GPHS composite material are presented.

  2. 7 CFR 240.1 - General purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... nonresidential child or adult care institutions participating in the Child and Adult Care Food Program (7 CFR... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS CASH IN LIEU OF DONATED FOODS § 240.1 General purpose and scope. (a)...

  3. 7 CFR 235.1 - General purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... part 220), the Child and Adult Care Food Program (7 CFR part 226) and the Food Distribution Program (7... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS STATE ADMINISTRATIVE EXPENSE FUNDS § 235.1 General purpose and...

  4. 22 CFR 305.1 - Purpose and general guideline.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Purpose and general guideline. 305.1 Section 305.1 Foreign Relations PEACE CORPS ELIGIBILITY AND STANDARDS FOR PEACE CORPS VOLUNTEER SERVICE § 305.1..., sex, creed, or color.” Further, in accordance with section 417(c)(1) of the Domestic Volunteer...

  5. 22 CFR 305.1 - Purpose and general guideline.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Purpose and general guideline. 305.1 Section 305.1 Foreign Relations PEACE CORPS ELIGIBILITY AND STANDARDS FOR PEACE CORPS VOLUNTEER SERVICE § 305.1..., sex, creed, or color.” Further, in accordance with section 417(c)(1) of the Domestic Volunteer...

  6. 22 CFR 305.1 - Purpose and general guideline.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Purpose and general guideline. 305.1 Section 305.1 Foreign Relations PEACE CORPS ELIGIBILITY AND STANDARDS FOR PEACE CORPS VOLUNTEER SERVICE § 305.1..., sex, creed, or color.” Further, in accordance with section 417(c)(1) of the Domestic Volunteer...

  7. 7 CFR 220.1 - General purpose and scope.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SCHOOL BREAKFAST PROGRAM § 220.1 General purpose and scope. This part... the Child Nutrition Act of 1966, as amended, which authorizes payments to the States to assist them...

  8. 21 CFR 864.4010 - General purpose reagent.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... is used to collect, prepare, and examine specimens from the human body for diagnostic purposes, and... Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... diagnostic test procedure or system constituting a finished in vitro diagnostic (IVD) test. General...

  9. A Small Acoustic Goniometer for General Purpose Research.

    PubMed

    Pook, Michael L; Loo, Sin Ming

    2016-01-01

    Understanding acoustic events and monitoring their occurrence is a useful aspect of many research projects. In particular, acoustic goniometry allows researchers to determine the source of an event based solely on the sound it produces. The vast majority of acoustic goniometry research projects used custom hardware targeted to the specific application under test. Unfortunately, due to the wide range of sensing applications, a flexible general purpose hardware/firmware system does not exist for this purpose. This article focuses on the development of such a system which encourages the continued exploration of general purpose hardware/firmware and lowers barriers to research in projects requiring the use of acoustic goniometry. Simulations have been employed to verify system feasibility, and a complete hardware implementation of the acoustic goniometer has been designed and field tested. The results are reported, and suggested areas for improvement and further exploration are discussed. PMID:27136563

  10. A Small Acoustic Goniometer for General Purpose Research

    PubMed Central

    Pook, Michael L.; Loo, Sin Ming

    2016-01-01

    Understanding acoustic events and monitoring their occurrence is a useful aspect of many research projects. In particular, acoustic goniometry allows researchers to determine the source of an event based solely on the sound it produces. The vast majority of acoustic goniometry research projects used custom hardware targeted to the specific application under test. Unfortunately, due to the wide range of sensing applications, a flexible general purpose hardware/firmware system does not exist for this purpose. This article focuses on the development of such a system which encourages the continued exploration of general purpose hardware/firmware and lowers barriers to research in projects requiring the use of acoustic goniometry. Simulations have been employed to verify system feasibility, and a complete hardware implementation of the acoustic goniometer has been designed and field tested. The results are reported, and suggested areas for improvement and further exploration are discussed. PMID:27136563

  11. Speed Control of General Purpose Engine with Electronic Governor

    NASA Astrophysics Data System (ADS)

    Sawut, Umerujan; Tohti, Gheyret; Takigawa, Buso; Tsuji, Teruo

    This paper presents a general purpose engine speed control system with an electronic governor in order to improve the current system with a mechanical governor which shows unstable characteristics by change of mecanical friction or A/F ratio (Air/Fuel ratio). For the control system above, there are problems that the feedback signal is only a crank angle because of cost and the controlled object is a general purpose engine which is strongly nonlinear. In order to overcome these problems, the system model is shown for the dynamic estimation of the amount of air flow and the robust controller is designed. That is, the proposed system includes the robust sliding-mode controller by the feedback signal of only a crank angle where Genetic Algorithm is applied for the controller design. The simulation and the experiments by MATLAB/Simulink are performed to show the effectiveness of our proposal.

  12. General-Purpose Serial Interface For Remote Control

    NASA Technical Reports Server (NTRS)

    Busquets, Anthony M.; Gupton, Lawrence E.

    1990-01-01

    Computer controls remote television camera. General-purpose controller developed to serve as interface between host computer and pan/tilt/zoom/focus functions on series of automated video cameras. Interface port based on 8251 programmable communications-interface circuit configured for tristated outputs, and connects controller system to any host computer with RS-232 input/output (I/O) port. Accepts byte-coded data from host, compares them with prestored codes in read-only memory (ROM), and closes or opens appropriate switches. Six output ports control opening and closing of as many as 48 switches. Operator controls remote television camera by speaking commands, in system including general-purpose controller.

  13. Linear equations in general purpose codes for stiff ODEs

    SciTech Connect

    Shampine, L. F.

    1980-02-01

    It is noted that it is possible to improve significantly the handling of linear problems in a general-purpose code with very little trouble to the user or change to the code. In such situations analytical evaluation of the Jacobian is a lot cheaper than numerical differencing. A slight change in the point at which the Jacobian is evaluated results in a more accurate Jacobian in linear problems. (RWR)

  14. New Generation General Purpose Computer (GPC) compact IBM unit

    NASA Technical Reports Server (NTRS)

    1991-01-01

    New Generation General Purpose Computer (GPC) compact IBM unit replaces a two-unit earlier generation computer. The new IBM unit is documented in table top views alone (S91-26867, S91-26868), with the onboard equipment it supports including the flight deck CRT screen and keypad (S91-26866), and next to the two earlier versions it replaces (S91-26869).

  15. A General-Purpose Mesh Generator for Finite Element Codes.

    1984-02-28

    Version 00 INGEN is a general-purpose mesh generator for use in conjunction with two and three dimensional finite element programs. The basic components of INGEN are surface and three-dimensional region generators that use linear-blending interpolation formulae. These generators are based on an i, j, k index scheme, which is used to number nodal points, construct elements, and develop displacement and traction boundary conditions.

  16. The parser generator as a general purpose tool

    NASA Technical Reports Server (NTRS)

    Noonan, R. E.; Collins, W. R.

    1985-01-01

    The parser generator has proven to be an extremely useful, general purpose tool. It can be used effectively by programmers having only a knowledge of grammars and no training at all in the theory of formal parsing. Some of the application areas for which a table-driven parser can be used include interactive, query languages, menu systems, translators, and programming support tools. Each of these is illustrated by an example grammar.

  17. A General Purpose Stacking Technique to Analyze Low Brightness Signal

    NASA Astrophysics Data System (ADS)

    Wavle, Daniel; Leroy, Adam K.; Donovan Meyer, Jennifer

    2015-01-01

    We present an implementation of a general purpose stacking technique in which the detections of bright emission lines are used as priors to analyze low-brightness signal. We demonstrate the use of the technique on ALMA observations of the nuclear region of the nearby galaxy NGC 253 but emphasize its general applicability to a wide class of problems. The conceptual basis for the technique is to use closely associated brighter lines as priors to establish the local velocity (and potentially velocity profile) of a faint line. With this prior, the faint line can be coherently averaged by assuming that it shares a mean velocity with the bright prior. The coherent spectral averaging allows one to more clearly distinguish real astronomical signals from systematic effects, unstable baselines, or imaging artifacts. In our example application, we apply the technique to measure the intensity of faint isotopologues of dense gas tracers in NGC 253, lines that are otherwise hard to distinguish from the noise. The implementation of the code is intended for release as a general purpose cube analysis tool compatible with other astronomical python packages.

  18. CRUSH TESTING OF 9977 GENERAL PURPOSE FISSILE PACKAGINGS

    SciTech Connect

    Smith, A.

    2010-07-28

    The 9977 General Purpose Fissile Package (GPFP) was designed in response to the adoption of the crush test requirement in the US regulations for packages for radioactive materials (10 CFR 71). This presentation on crush testing of the 9977 GPFP Reviews origins of Crush Test Requirements and implementation of crush test requirements in 10 CFR 71. SANDIA testing performed to support the rule making is reviewed. The differences in practice, on the part of the US Department of Energy from those required by the NRC for commercial purposes, are explained. The design features incorporated into the 9977 GPFP to enable it to withstand the crush test and the crush tests performed on the 9977 are described. Lessons learned from crush testing of GPFP packagings are given.

  19. Installation of new Generation General Purpose Computer (GPC) compact unit

    NASA Technical Reports Server (NTRS)

    1991-01-01

    In the Kennedy Space Center's (KSC's) Orbiter Processing Facility (OPF) high bay 2, Spacecraft Electronics technician Ed Carter (right), wearing clean suit, prepares for (26864) and installs (26865) the new Generation General Purpose Computer (GPC) compact IBM unit in Atlantis', Orbiter Vehicle (OV) 104's, middeck avionics bay as Orbiter Systems Quality Control technician Doug Snider looks on. Both men work for NASA contractor Lockheed Space Operations Company. All three orbiters are being outfitted with the compact IBM unit, which replaces a two-unit earlier generation computer.

  20. Development of a General Purpose Power System Control Board

    SciTech Connect

    Nam, S.H.; Jeong, S.H.; Kim, S.H.; Kim, S.C.; Park, S.S.; Suh, J.H.; Bellomo, P.; Cassel, R.; Larsen, R.; Nguyen, M.N.; /SLAC

    2007-07-23

    In an effort to control modern solid state power modules, a general purpose, multi function power system control board (PSCB) has been under development as a collaboration project between Pohang Accelerator Laboratory (PAL), Korea, and Stanford Linear Accelerator Center (SLAC), USA. The PSCB is an embedded, interlock supervisory, diagnostic, timing, and set-point control board. It is designed to use in various power systems such as sequenced kicker pulsers, solid state RF modulators, simple DC magnet power supplies, etc. The PSCB has the Ethernet communication with the TCP/IP Modbus protocol.

  1. A structural and functional homolog supports a general role for frataxin in cellular iron chemistry.

    PubMed

    Qi, Wenbin; Cowan, J A

    2010-02-01

    Bacillus subtilis YdhG lacks sequence homology, but demonstrates structural and functional similarity to the frataxin family, supporting a general cellular role for frataxin-type proteins in cellular iron homeostasis.

  2. General purpose multiplexing device for cryogenic microwave systems

    NASA Astrophysics Data System (ADS)

    Chapman, Benjamin J.; Moores, Bradley A.; Rosenthal, Eric I.; Kerckhoff, Joseph; Lehnert, K. W.

    2016-05-01

    We introduce and experimentally characterize a general purpose device for signal processing in circuit quantum electrodynamics systems. The device is a broadband two-port microwave circuit element with three modes of operation: it can transmit, reflect, or invert incident signals between 4 and 8 GHz. This property makes it a versatile tool for lossless signal processing at cryogenic temperatures. In particular, rapid switching (≤ 15 ns ) between these operation modes enables several multiplexing readout protocols for superconducting qubits. We report the device's performance in a two-channel code domain multiplexing demonstration. The multiplexed data are recovered with fast readout times (up to 400 ns ) and infidelities ≤ 10-2 for probe powers ≥ 7 fW , in agreement with the expectation for binary signaling with Gaussian noise.

  3. Toward a General-Purpose Heterogeneous Ensemble for Pattern Classification

    PubMed Central

    Nanni, Loris; Brahnam, Sheryl; Ghidoni, Stefano; Lumini, Alessandra

    2015-01-01

    We perform an extensive study of the performance of different classification approaches on twenty-five datasets (fourteen image datasets and eleven UCI data mining datasets). The aim is to find General-Purpose (GP) heterogeneous ensembles (requiring little to no parameter tuning) that perform competitively across multiple datasets. The state-of-the-art classifiers examined in this study include the support vector machine, Gaussian process classifiers, random subspace of adaboost, random subspace of rotation boosting, and deep learning classifiers. We demonstrate that a heterogeneous ensemble based on the simple fusion by sum rule of different classifiers performs consistently well across all twenty-five datasets. The most important result of our investigation is demonstrating that some very recent approaches, including the heterogeneous ensemble we propose in this paper, are capable of outperforming an SVM classifier (implemented with LibSVM), even when both kernel selection and SVM parameters are carefully tuned for each dataset. PMID:26413089

  4. Using a cognitive architecture for general purpose service robot control

    NASA Astrophysics Data System (ADS)

    Puigbo, Jordi-Ysard; Pumarola, Albert; Angulo, Cecilio; Tellez, Ricardo

    2015-04-01

    A humanoid service robot equipped with a set of simple action skills including navigating, grasping, recognising objects or people, among others, is considered in this paper. By using those skills the robot should complete a voice command expressed in natural language encoding a complex task (defined as the concatenation of a number of those basic skills). As a main feature, no traditional planner has been used to decide skills to be activated, as well as in which sequence. Instead, the SOAR cognitive architecture acts as the reasoner by selecting which action the robot should complete, addressing it towards the goal. Our proposal allows to include new goals for the robot just by adding new skills (without the need to encode new plans). The proposed architecture has been tested on a human-sized humanoid robot, REEM, acting as a general purpose service robot.

  5. A Chemical Containment Model for the General Purpose Work Station

    NASA Technical Reports Server (NTRS)

    Flippen, Alexis A.; Schmidt, Gregory K.

    1994-01-01

    Contamination control is a critical safety requirement imposed on experiments flying on board the Spacelab. The General Purpose Work Station, a Spacelab support facility used for life sciences space flight experiments, is designed to remove volatile compounds from its internal airpath and thereby minimize contamination of the Spacelab. This is accomplished through the use of a large, multi-stage filter known as the Trace Contaminant Control System. Many experiments planned for the Spacelab require the use of toxic, volatile fixatives in order to preserve specimens prior to postflight analysis. The NASA-Ames Research Center SLS-2 payload, in particular, necessitated the use of several toxic, volatile compounds in order to accomplish the many inflight experiment objectives of this mission. A model was developed based on earlier theories and calculations which provides conservative predictions of the resultant concentrations of these compounds given various spill scenarios. This paper describes the development and application of this model.

  6. General-Purpose Detectors for the Large Hadron Collider

    NASA Astrophysics Data System (ADS)

    Froidevaux, Daniel; Sphicas, Paris

    2006-11-01

    This review describes the two general-purpose experiments, ATLAS and CMS, that have been designed to study proton-proton collisions at 14 TeV, the highest center-of-mass energy ever achieved, at the Large Hadron Collider at CERN in Geneva, Switzerland. These experiments have undergone a long research and development and construction period since 1989 and are now in the middle of a strenuous and exciting integration, installation, and commissioning period. After a brief introduction to the physics context and prospects as perceived today, this review presents an overview of both projects in terms of their global design characteristics. The main features and challenges related to the tracking systems, to the calorimetry, and to the muon spectrometers are described. The various aspects of the trigger and data acquisition systems and of the computing and software are also discussed broadly. Finally, we conclude with the lessons learned during the design and construction years.

  7. General purpose symbolic simulation tools for electric networks

    SciTech Connect

    Alvarado, F.L.; Lui, Y.

    1988-05-01

    This paper presents research results on the use of computers to solve simulation problems in a way closer to human thinking. With the aid of techniques in AI (Artificial Intelligence), DB (Data Base Systems), and Computer Graphics, a set of general purpose LISP and PASCAL based simulation tools have been developed. Each of these tools solves a specific problem in some stage of simulation. Rule-based and object-oriented symbolic manipulations are extensively used. The tools provide more powerful and accurate modelling capability for complex objects, and permit simplicity and flexibility in implementation. The tools are used to study electrical transient problems, optimal load flow problems, linear control systems, and other simulation problems.

  8. General-Purpose Data-Formatting Input/Output System

    NASA Technical Reports Server (NTRS)

    Busquets, Anthony M.; Hogge, Thomas W.

    1990-01-01

    Multiplexable input/output (I/O) system developed as interface between host computer and real-time, fixed-base simulator cockpit. Unit designed to be general-purpose interface and operated through virtually any 8- or 16-bit, transistor/transistor-logic-level, parallel-I/O port with or without handshaking. Accepts byte-coded data in form of data blocks from host computer and routes data to various system I/O modules like discrete outputs, lamp drivers, and seven-segment-display drivers. Formats and routes data from input modules back to host computer. Other modules designed to drive alphanumeric displays and communications interfaces and to serve as analog-to-digital and digital-to-analog converter modules.

  9. ALEPH2 - A general purpose Monte Carlo depletion code

    SciTech Connect

    Stankovskiy, A.; Van Den Eynde, G.; Baeten, P.; Trakas, C.; Demy, P. M.; Villatte, L.

    2012-07-01

    The Monte-Carlo burn-up code ALEPH is being developed at SCK-CEN since 2004. A previous version of the code implemented the coupling between the Monte Carlo transport (any version of MCNP or MCNPX) and the ' deterministic' depletion code ORIGEN-2.2 but had important deficiencies in nuclear data treatment and limitations inherent to ORIGEN-2.2. A new version of the code, ALEPH2, has several unique features making it outstanding among other depletion codes. The most important feature is full data consistency between steady-state Monte Carlo and time-dependent depletion calculations. The last generation general-purpose nuclear data libraries (JEFF-3.1.1, ENDF/B-VII and JENDL-4) are fully implemented, including special purpose activation, spontaneous fission, fission product yield and radioactive decay data. The built-in depletion algorithm allows to eliminate the uncertainties associated with obtaining the time-dependent nuclide concentrations. A predictor-corrector mechanism, calculation of nuclear heating, calculation of decay heat, decay neutron sources are available as well. The validation of the code on the results of REBUS experimental program has been performed. The ALEPH2 has shown better agreement with measured data than other depletion codes. (authors)

  10. Use of general purpose graphics processing units with MODFLOW

    USGS Publications Warehouse

    Hughes, Joseph D.; White, Jeremy T.

    2013-01-01

    To evaluate the use of general-purpose graphics processing units (GPGPUs) to improve the performance of MODFLOW, an unstructured preconditioned conjugate gradient (UPCG) solver has been developed. The UPCG solver uses a compressed sparse row storage scheme and includes Jacobi, zero fill-in incomplete, and modified-incomplete lower-upper (LU) factorization, and generalized least-squares polynomial preconditioners. The UPCG solver also includes options for sequential and parallel solution on the central processing unit (CPU) using OpenMP. For simulations utilizing the GPGPU, all basic linear algebra operations are performed on the GPGPU; memory copies between the central processing unit CPU and GPCPU occur prior to the first iteration of the UPCG solver and after satisfying head and flow criteria or exceeding a maximum number of iterations. The efficiency of the UPCG solver for GPGPU and CPU solutions is benchmarked using simulations of a synthetic, heterogeneous unconfined aquifer with tens of thousands to millions of active grid cells. Testing indicates GPGPU speedups on the order of 2 to 8, relative to the standard MODFLOW preconditioned conjugate gradient (PCG) solver, can be achieved when (1) memory copies between the CPU and GPGPU are optimized, (2) the percentage of time performing memory copies between the CPU and GPGPU is small relative to the calculation time, (3) high-performance GPGPU cards are utilized, and (4) CPU-GPGPU combinations are used to execute sequential operations that are difficult to parallelize. Furthermore, UPCG solver testing indicates GPGPU speedups exceed parallel CPU speedups achieved using OpenMP on multicore CPUs for preconditioners that can be easily parallelized.

  11. Use of general purpose graphics processing units with MODFLOW.

    PubMed

    Hughes, Joseph D; White, Jeremy T

    2013-01-01

    To evaluate the use of general-purpose graphics processing units (GPGPUs) to improve the performance of MODFLOW, an unstructured preconditioned conjugate gradient (UPCG) solver has been developed. The UPCG solver uses a compressed sparse row storage scheme and includes Jacobi, zero fill-in incomplete, and modified-incomplete lower-upper (LU) factorization, and generalized least-squares polynomial preconditioners. The UPCG solver also includes options for sequential and parallel solution on the central processing unit (CPU) using OpenMP. For simulations utilizing the GPGPU, all basic linear algebra operations are performed on the GPGPU; memory copies between the central processing unit CPU and GPCPU occur prior to the first iteration of the UPCG solver and after satisfying head and flow criteria or exceeding a maximum number of iterations. The efficiency of the UPCG solver for GPGPU and CPU solutions is benchmarked using simulations of a synthetic, heterogeneous unconfined aquifer with tens of thousands to millions of active grid cells. Testing indicates GPGPU speedups on the order of 2 to 8, relative to the standard MODFLOW preconditioned conjugate gradient (PCG) solver, can be achieved when (1) memory copies between the CPU and GPGPU are optimized, (2) the percentage of time performing memory copies between the CPU and GPGPU is small relative to the calculation time, (3) high-performance GPGPU cards are utilized, and (4) CPU-GPGPU combinations are used to execute sequential operations that are difficult to parallelize. Furthermore, UPCG solver testing indicates GPGPU speedups exceed parallel CPU speedups achieved using OpenMP on multicore CPUs for preconditioners that can be easily parallelized. PMID:23281733

  12. Use of general purpose graphics processing units with MODFLOW.

    PubMed

    Hughes, Joseph D; White, Jeremy T

    2013-01-01

    To evaluate the use of general-purpose graphics processing units (GPGPUs) to improve the performance of MODFLOW, an unstructured preconditioned conjugate gradient (UPCG) solver has been developed. The UPCG solver uses a compressed sparse row storage scheme and includes Jacobi, zero fill-in incomplete, and modified-incomplete lower-upper (LU) factorization, and generalized least-squares polynomial preconditioners. The UPCG solver also includes options for sequential and parallel solution on the central processing unit (CPU) using OpenMP. For simulations utilizing the GPGPU, all basic linear algebra operations are performed on the GPGPU; memory copies between the central processing unit CPU and GPCPU occur prior to the first iteration of the UPCG solver and after satisfying head and flow criteria or exceeding a maximum number of iterations. The efficiency of the UPCG solver for GPGPU and CPU solutions is benchmarked using simulations of a synthetic, heterogeneous unconfined aquifer with tens of thousands to millions of active grid cells. Testing indicates GPGPU speedups on the order of 2 to 8, relative to the standard MODFLOW preconditioned conjugate gradient (PCG) solver, can be achieved when (1) memory copies between the CPU and GPGPU are optimized, (2) the percentage of time performing memory copies between the CPU and GPGPU is small relative to the calculation time, (3) high-performance GPGPU cards are utilized, and (4) CPU-GPGPU combinations are used to execute sequential operations that are difficult to parallelize. Furthermore, UPCG solver testing indicates GPGPU speedups exceed parallel CPU speedups achieved using OpenMP on multicore CPUs for preconditioners that can be easily parallelized.

  13. Generalized Fluid System Simulation Program (GFSSP) Version 6 - General Purpose Thermo-Fluid Network Analysis Software

    NASA Technical Reports Server (NTRS)

    Majumdar, Alok; Leclair, Andre; Moore, Ric; Schallhorn, Paul

    2011-01-01

    GFSSP stands for Generalized Fluid System Simulation Program. It is a general-purpose computer program to compute pressure, temperature and flow distribution in a flow network. GFSSP calculates pressure, temperature, and concentrations at nodes and calculates flow rates through branches. It was primarily developed to analyze Internal Flow Analysis of a Turbopump Transient Flow Analysis of a Propulsion System. GFSSP development started in 1994 with an objective to provide a generalized and easy to use flow analysis tool for thermo-fluid systems.

  14. General purpose, field-portable cell-based biosensor platform.

    PubMed

    Gilchrist, K H; Barker, V N; Fletcher, L E; DeBusschere, B D; Ghanouni, P; Giovangrandi, L; Kovacs, G T

    2001-09-01

    There are several groups of researchers developing cell-based biosensors for chemical and biological warfare agents based on electrophysiologic monitoring of cells. In order to transition such sensors from the laboratory to the field, a general-purpose hardware and software platform is required. This paper describes the design, implementation, and field-testing of such a system, consisting of cell-transport and data acquisition instruments. The cell-transport module is a self-contained, battery-powered instrument that allows various types of cell-based modules to be maintained at a preset temperature and ambient CO(2) level while in transit or in the field. The data acquisition module provides 32 channels of action potential amplification, filtering, and real-time data streaming to a laptop computer. At present, detailed analysis of the data acquired is carried out off-line, but sufficient computing power is available in the data acquisition module to enable the most useful algorithms to eventually be run real-time in the field. Both modules have sufficient internal power to permit realistic field-testing, such as the example presented in this paper. PMID:11544049

  15. General-purpose event generators for LHC physics

    SciTech Connect

    Buckley, Andy; Butterworth, Jonathan; Gieseke, Stefan; Grellscheid, David; Hoche, Stefan; Hoeth, Hendrik; Krauss, Frank; Lonnblad, Leif; Nurse, Emily; Richardson, Peter; Schumann, Steffen; Seymour, Michael H.; Sjostrand, Torbjorn; Skands, Peter; Webber, Bryan; /Cambridge U.

    2011-03-03

    We review the physics basis, main features and use of general-purpose Monte Carlo event generators for the simulation of proton-proton collisions at the Large Hadron Collider. Topics included are: the generation of hard-scattering matrix elements for processes of interest, at both leading and next-to-leading QCD perturbative order; their matching to approximate treatments of higher orders based on the showering approximation; the parton and dipole shower formulations; parton distribution functions for event generators; non-perturbative aspects such as soft QCD collisions, the underlying event and diffractive processes; the string and cluster models for hadron formation; the treatment of hadron and tau decays; the inclusion of QED radiation and beyond-Standard-Model processes. We describe the principal features of the Ariadne, Herwig++, Pythia 8 and Sherpa generators, together with the Rivet and Professor validation and tuning tools, and discuss the physics philosophy behind the proper use of these generators and tools. This review is aimed at phenomenologists wishing to understand better how parton-level predictions are translated into hadron-level events as well as experimentalists wanting a deeper insight into the tools available for signal and background simulation at the LHC.

  16. High-Speed General Purpose Genetic Algorithm Processor.

    PubMed

    Hoseini Alinodehi, Seyed Pourya; Moshfe, Sajjad; Saber Zaeimian, Masoumeh; Khoei, Abdollah; Hadidi, Khairollah

    2016-07-01

    In this paper, an ultrafast steady-state genetic algorithm processor (GAP) is presented. Due to the heavy computational load of genetic algorithms (GAs), they usually take a long time to find optimum solutions. Hardware implementation is a significant approach to overcome the problem by speeding up the GAs procedure. Hence, we designed a digital CMOS implementation of GA in [Formula: see text] process. The proposed processor is not bounded to a specific application. Indeed, it is a general-purpose processor, which is capable of performing optimization in any possible application. Utilizing speed-boosting techniques, such as pipeline scheme, parallel coarse-grained processing, parallel fitness computation, parallel selection of parents, dual-population scheme, and support for pipelined fitness computation, the proposed processor significantly reduces the processing time. Furthermore, by relying on a built-in discard operator the proposed hardware may be used in constrained problems that are very common in control applications. In the proposed design, a large search space is achievable through the bit string length extension of individuals in the genetic population by connecting the 32-bit GAPs. In addition, the proposed processor supports parallel processing, in which the GAs procedure can be run on several connected processors simultaneously.

  17. Programming methodology for a general purpose automation controller

    NASA Technical Reports Server (NTRS)

    Sturzenbecker, M. C.; Korein, J. U.; Taylor, R. H.

    1987-01-01

    The General Purpose Automation Controller is a multi-processor architecture for automation programming. A methodology has been developed whose aim is to simplify the task of programming distributed real-time systems for users in research or manufacturing. Programs are built by configuring function blocks (low-level computations) into processes using data flow principles. These processes are activated through the verb mechanism. Verbs are divided into two classes: those which support devices, such as robot joint servos, and those which perform actions on devices, such as motion control. This programming methodology was developed in order to achieve the following goals: (1) specifications for real-time programs which are to a high degree independent of hardware considerations such as processor, bus, and interconnect technology; (2) a component approach to software, so that software required to support new devices and technologies can be integrated by reconfiguring existing building blocks; (3) resistance to error and ease of debugging; and (4) a powerful command language interface.

  18. Nondestructive inspection of General Purpose Heat Source (GPHS) girth welds

    SciTech Connect

    Reimus, M.A.H.; George, T.G.; Lynch, C.

    1998-12-31

    The General-Purpose Heat Source (GPHS) provides power for space missions by transmitting the heat of {sup 238}Pu decay to an array of thermoelectric elements. The GPHS is fabricated using iridium capsules, TIG welded, to contain the {sup 238}PuO{sub 2} fuel pellet. GPHS capsules will be utilized in the upcoming Cassini mission to explore Saturn and its moons. The physical integrity of the girth weld is important to mission safety and performance. Since experience in the past had revealed a potential for initiation of small cracks in the girth weld overlap zone, a nondestructive inspection of the capsule weld is required. A ultrasonic method was used to inspect the welds of capsules fabricated for the Galileo mission. The instrument, transducer, and method used were state of the art at the time (early 1980s). The ultrasonic instrumentation and methods used to inspect the Cassini GPHSs was significantly upgraded from those used for the Galileo mission. GPHSs that had ultrasonic reflectors that exceeded the reject specification level were subsequently inspected with radiography to provide additional engineering data used to accept/reject the heat source. This paper describes the Galileo-era ultrasonic instrumentation and methods and the subsequent upgrades made to support testing of Cassini GPHSs. Also discussed is the data obtained from radiographic examination and correlation to ultrasonic examination results.

  19. The General Purpose Work Station, a spacious microgravity workbench

    NASA Technical Reports Server (NTRS)

    Dalton, Bonnie P.; Schmidt, Greg K.; Savage, P. D.

    1992-01-01

    The General Purpose Work Station (GPWS) is a laboratory multiuse facility, as demonstrated during the Spacelab Life Sciences 1 (SLS-1) flight. The unit provided particulate containment under varying conditions, served as an effective work space for manipulating live animals, e.g., rats, served as a containment facility for fixatives, and was proposed for use to conduct in-flight maintenance during connector pin repair. The cabinet has a front door large enough to allow installation of a full-size microscope in-flight and is outfitted with a side window to allow delivery of items into the cabinet without exposure to the spacelab atmosphere. Additional support subsystems include inside cabinet mounting, surgical glove fine manipulations capability, and ac or dc power supply for experiment equipment, as will be demonstrated during Spacelab J. The GPWS, integrated and maintained in a double flight-rack, interfaces to spacelab systems including water cooling, avionics and cabin air, and power. Verification has been completed for multiple spacelab scenarios including SLS-2, SL-J, and SLS-3.

  20. CLOUDCLOUD : general-purpose instrument monitoring and data managing software

    NASA Astrophysics Data System (ADS)

    Dias, António; Amorim, António; Tomé, António

    2016-04-01

    An effective experiment is dependent on the ability to store and deliver data and information to all participant parties regardless of their degree of involvement in the specific parts that make the experiment a whole. Having fast, efficient and ubiquitous access to data will increase visibility and discussion, such that the outcome will have already been reviewed several times, strengthening the conclusions. The CLOUD project aims at providing users with a general purpose data acquisition, management and instrument monitoring platform that is fast, easy to use, lightweight and accessible to all participants of an experiment. This work is now implemented in the CLOUD experiment at CERN and will be fully integrated with the experiment as of 2016. Despite being used in an experiment of the scale of CLOUD, this software can also be used in any size of experiment or monitoring station, from single computers to large networks of computers to monitor any sort of instrument output without influencing the individual instrument's DAQ. Instrument data and meta data is stored and accessed via a specially designed database architecture and any type of instrument output is accepted using our continuously growing parsing application. Multiple databases can be used to separate different data taking periods or a single database can be used if for instance an experiment is continuous. A simple web-based application gives the user total control over the monitored instruments and their data, allowing data visualization and download, upload of processed data and the ability to edit existing instruments or add new instruments to the experiment. When in a network, new computers are immediately recognized and added to the system and are able to monitor instruments connected to them. Automatic computer integration is achieved by a locally running python-based parsing agent that communicates with a main server application guaranteeing that all instruments assigned to that computer are

  1. RoboCon: A general purpose telerobotic control center

    SciTech Connect

    Draper, J.V.; Noakes, M.W.; Schempf, H.; Blair, L.M.

    1997-02-01

    This report describes human factors issues involved in the design of RoboCon, a multi-purpose control center for use in US Department of Energy remote handling applications. RoboCon is intended to be a flexible, modular control center capable of supporting a wide variety of robotic devices.

  2. A General Purpose Connections type CTI Server Based on SIP Protocol and Its Implementation

    NASA Astrophysics Data System (ADS)

    Watanabe, Toru; Koizumi, Hisao

    In this paper, we propose a general purpose connections type CTI (Computer Telephony Integration) server that provides various CTI services such as voice logging where the CTI server communicates with IP-PBX using the SIP (Session Initiation Protocol), and accumulates voice packets of external line telephone call flowing between an IP telephone for extension and a VoIP gateway connected to outside line networks. The CTI server realizes CTI services such as voice logging, telephone conference, or IVR (interactive voice response) with accumulating and processing voice packets sampled. Furthermore, the CTI server incorporates a web server function which can provide various CTI services such as a Web telephone directory via a Web browser to PCs, cellular telephones or smart-phones in mobile environments.

  3. 47 CFR 32.2124 - General purpose computers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... devices which are designed to perform general administrative information processing activities. (b) Administrative information processing includes but is not limited to activities such as the preparation of... cash management reports, and other records and reports not specifically designed for testing,...

  4. General Education at Broome Community College: Coherence and Purpose.

    ERIC Educational Resources Information Center

    Romano, Richard M.

    1995-01-01

    Describes the general education program adopted by New York's Broome Community College after eight years of debate and a full campus vote. Indicates that the program includes a core of academic requirements and incorporates communication, civic, global, critical thinking, moral, mathematical, scientific, technological, and health education…

  5. 7 CFR 3201.37 - General purpose de-icers.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) that are designed to aid in the removal of snow and/or ice, and/or in the prevention of the buildup of snow and/or ice, in general use applications by lowering the freezing point of water. Specialized...

  6. 7 CFR 3201.37 - General purpose de-icers.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) that are designed to aid in the removal of snow and/or ice, and/or in the prevention of the buildup of snow and/or ice, in general use applications by lowering the freezing point of water. Specialized...

  7. 7 CFR 3201.37 - General purpose de-icers.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) that are designed to aid in the removal of snow and/or ice, and/or in the prevention of the buildup of snow and/or ice, in general use applications by lowering the freezing point of water. Specialized...

  8. 24 CFR 902.1 - Purpose and general description.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... (addressed in subpart C of this part); (3) PHAS Indicator #3—the management operations of a PHA (addressed in... management operations and resident services and satisfaction, respectively. On the basis of this data, REAC... agencies (PHAs), public housing residents, HUD and the general public by providing a management tool...

  9. Recent technical advances in general purpose mobile Satcom aviation terminals

    NASA Technical Reports Server (NTRS)

    Sydor, John T.

    1990-01-01

    A second general aviation amplitude companded single sideband (ACSSB) aeronautical terminal was developed for use with the Ontario Air Ambulance Service (OAAS). This terminal is designed to have automatic call set up and take down and to interface with the Public Service Telephone Network (PSTN) through a ground earth station hub controller. The terminal has integrated RF and microprocessor hardware which allows such functions as beam steering and automatic frequency control to be software controlled. The terminal uses a conformal patch array system to provide almost full azimuthal coverage. Antenna beam steering is executed without relying on aircraft supplied orientation information.

  10. PD5: A General Purpose Library for Primer Design Software

    PubMed Central

    Riley, Michael C.; Aubrey, Wayne; Young, Michael; Clare, Amanda

    2013-01-01

    Background Complex PCR applications for large genome-scale projects require fast, reliable and often highly sophisticated primer design software applications. Presently, such applications use pipelining methods to utilise many third party applications and this involves file parsing, interfacing and data conversion, which is slow and prone to error. A fully integrated suite of software tools for primer design would considerably improve the development time, the processing speed, and the reliability of bespoke primer design software applications. Results The PD5 software library is an open-source collection of classes and utilities, providing a complete collection of software building blocks for primer design and analysis. It is written in object-oriented C++ with an emphasis on classes suitable for efficient and rapid development of bespoke primer design programs. The modular design of the software library simplifies the development of specific applications and also integration with existing third party software where necessary. We demonstrate several applications created using this software library that have already proved to be effective, but we view the project as a dynamic environment for building primer design software and it is open for future development by the bioinformatics community. Therefore, the PD5 software library is published under the terms of the GNU General Public License, which guarantee access to source-code and allow redistribution and modification. Conclusions The PD5 software library is downloadable from Google Code and the accompanying Wiki includes instructions and examples: http://code.google.com/p/primer-design PMID:24278254

  11. General purpose architecture for intelligent computer-aided training

    NASA Technical Reports Server (NTRS)

    Loftin, R. Bowen (Inventor); Wang, Lui (Inventor); Baffes, Paul T. (Inventor); Hua, Grace C. (Inventor)

    1994-01-01

    An intelligent computer-aided training system having a general modular architecture is provided for use in a wide variety of training tasks and environments. It is comprised of a user interface which permits the trainee to access the same information available in the task environment and serves as a means for the trainee to assert actions to the system; a domain expert which is sufficiently intelligent to use the same information available to the trainee and carry out the task assigned to the trainee; a training session manager for examining the assertions made by the domain expert and by the trainee for evaluating such trainee assertions and providing guidance to the trainee which are appropriate to his acquired skill level; a trainee model which contains a history of the trainee interactions with the system together with summary evaluative data; an intelligent training scenario generator for designing increasingly complex training exercises based on the current skill level contained in the trainee model and on any weaknesses or deficiencies that the trainee has exhibited in previous interactions; and a blackboard that provides a common fact base for communication between the other components of the system. Preferably, the domain expert contains a list of 'mal-rules' which typifies errors that are usually made by novice trainees. Also preferably, the training session manager comprises an intelligent error detection means and an intelligent error handling means. The present invention utilizes a rule-based language having a control structure whereby a specific message passing protocol is utilized with respect to tasks which are procedural or step-by-step in structure. The rules can be activated by the trainee in any order to reach the solution by any valid or correct path.

  12. 41 CFR 60-741.40 - General purpose and applicability of the affirmative action program requirement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... requirement. (a) General purpose. An affirmative action program is a management tool designed to ensure equal... measurable objectives, quantitative analyses, and internal auditing and reporting systems that measure...

  13. 41 CFR 60-2.10 - General purpose and contents of affirmative action programs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... contents of affirmative action programs. 60-2.10 Section 60-2.10 Public Contracts and Property Management... EMPLOYMENT OPPORTUNITY, DEPARTMENT OF LABOR 2-AFFIRMATIVE ACTION PROGRAMS Purpose and Contents of Affirmative Action Programs § 60-2.10 General purpose and contents of affirmative action programs. (a) Purpose....

  14. General purpose nonlinear system solver based on Newton-Krylov method.

    SciTech Connect

    2013-12-01

    KINSOL is part of a software family called SUNDIALS: SUite of Nonlinear and Differential/Algebraic equation Solvers [1]. KINSOL is a general-purpose nonlinear system solver based on Newton-Krylov and fixed-point solver technologies [2].

  15. 21 CFR 1240.80 - General requirements for water for drinking and culinary purposes.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false General requirements for water for drinking and... DRUG ADMINISTRATION CONTROL OF COMMUNICABLE DISEASES Source and Use of Potable Water § 1240.80 General requirements for water for drinking and culinary purposes. Only potable water shall be provided for...

  16. The role of overset grids in the development of the general purpose CFD code

    NASA Technical Reports Server (NTRS)

    Belk, Davy M.

    1995-01-01

    A discussion of the strengths and weaknesses of overset composite grid and solution technology is given, along with a sampling of current work in the area. Major trends are identified, and the observation is made that generalized and hybridized overset methods provide a natural framework for combining disparate mesh types and physics models. Because of this, the author concludes that overset methods will be the foundation for the general purpose computational fluid dynamics programs of the future.

  17. 41 CFR 60-2.10 - General purpose and contents of affirmative action programs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 41 Public Contracts and Property Management 1 2014-07-01 2014-07-01 false General purpose and contents of affirmative action programs. 60-2.10 Section 60-2.10 Public Contracts and Property Management...) An affirmative action program is a management tool designed to ensure equal employment opportunity....

  18. Selection and Use of General-Purpose Programming Languages--Overview. Volume 1.

    ERIC Educational Resources Information Center

    Cugini, John V.

    This study presents a review of selection factors for the seven major general-purpose programming languages: Ada, BASIC, C, COBOL, FORTRAN, PASCAL, and PL/I. The factors covered include not only the logical operations within each language, but also the advantages and disadvantages stemming from the current computing environment, e.g., software…

  19. Reentry thermal testing of a general purpose heat source fueled clad

    SciTech Connect

    Peterson, D.E.; Frantz, C.E.

    1982-03-01

    A General Purpose Heat Source (GPHS) module was exposed to heat treatments simulating an isothermal prelaunch condition, followed by thermal pulses corresponding to atmospheric reentry. Helium release rates were determined during each heating and modeled after simple diffusion theory. Following the tests, the module was examined metallurgically with no evidence of swelling of the cladding nor degradation of the fuel.

  20. Recruiting Gamblers from the General Population for Research Purposes: Outcomes from Two Contrasting Approaches

    ERIC Educational Resources Information Center

    Williams, Jeremy D.; Pulford, Justin; Bellringer, Maria; Abbott, Max

    2010-01-01

    Multiple means exist by which gamblers including problem gamblers may be recruited from the general population for research survey purposes. However, there appears to be limited discussion in the published literature about the relative merits of one or other approach. This paper addresses this gap, in part, by reporting the experiences of…

  1. An Evaluation of Classroom Activities and Exercises in ELT Classroom for General Purposes Course

    ERIC Educational Resources Information Center

    Zohrabi, Mohammad

    2011-01-01

    It is through effective implementation of activities and exercises which students can be motivated and consequently lead to language learning. However, as an insider, the experience of teaching English for General Purposes (EGP) course indicates that it has some problems which need to be modified. In order to evaluate the EGP course,…

  2. Research on Automatic Classification, Indexing and Extracting: A General-Purpose Frequency Program.

    ERIC Educational Resources Information Center

    Baker, F. T.; Williams, John H., Jr.

    To support studies in automatic indexing, classification and extracting, a general purpose frequency program was developed to further theoretical and practical understanding of text word distributions. While the program is primarily designed for counting strings of character-oriented data, it can be used without change for counting any items which…

  3. An Investigation of Learning Transfer in English-for-General-Academic-Purposes Writing Instruction

    ERIC Educational Resources Information Center

    James, Mark Andrew

    2010-01-01

    This case study involved a detailed examination of learning transfer from an English-for-general-academic-purposes writing course to tasks that involve writing in other academic courses. Data were gathered over one academic year from 11 students enrolled in the writing course. These students participated in a series of interviews and provided…

  4. 21 CFR 1240.80 - General requirements for water for drinking and culinary purposes.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false General requirements for water for drinking and culinary purposes. 1240.80 Section 1240.80 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION CONTROL OF...

  5. General purpose simulation system of the data management system for Space Shuttle mission 18

    NASA Technical Reports Server (NTRS)

    Bengtson, N. M.; Mellichamp, J. M.; Smith, O. C.

    1976-01-01

    A simulation program for the flow of data through the Data Management System of Spacelab and Space Shuttle was presented. The science, engineering, command and guidance, navigation and control data were included. The programming language used was General Purpose Simulation System V (OS). The science and engineering data flow was modeled from its origin at the experiments and subsystems to transmission from Space Shuttle. Command data flow was modeled from the point of reception onboard and from the CDMS Control Panel to the experiments and subsystems. The GN&C data flow model handled data between the General Purpose Computer and the experiments and subsystems. Mission 18 was the particular flight chosen for simulation. The general structure of the program is presented, followed by a user's manual. Input data required to make runs are discussed followed by identification of the output statistics. The appendices contain a detailed model configuration, program listing and results.

  6. Real-time radar signal processing using GPGPU (general-purpose graphic processing unit)

    NASA Astrophysics Data System (ADS)

    Kong, Fanxing; Zhang, Yan Rockee; Cai, Jingxiao; Palmer, Robert D.

    2016-05-01

    This study introduces a practical approach to develop real-time signal processing chain for general phased array radar on NVIDIA GPUs(Graphical Processing Units) using CUDA (Compute Unified Device Architecture) libraries such as cuBlas and cuFFT, which are adopted from open source libraries and optimized for the NVIDIA GPUs. The processed results are rigorously verified against those from the CPUs. Performance benchmarked in computation time with various input data cube sizes are compared across GPUs and CPUs. Through the analysis, it will be demonstrated that GPGPUs (General Purpose GPU) real-time processing of the array radar data is possible with relatively low-cost commercial GPUs.

  7. Forward Modeling of Electromagnetic Methods Using General Purpose Finite Element Software

    NASA Astrophysics Data System (ADS)

    Butler, S. L.

    2015-12-01

    Electromagnetic methods are widely used in mineral exploration and environmental applications and are increasingly being used in hydrocarbon exploration. Forward modeling of electromagnetic methods remains challenging and is mostly carried out using purpose-built research software. General purpose commercial modeling software has become increasingly flexible and powerful in recent years and is now capable of modeling field geophysical electromagnetic techniques. In this contribution, I will show examples of the use of commercial finite element modeling software Comsol Multiphysics for modeling frequency and time-domain electromagnetic techniques as well as for modeling the Very Low Frequency technique and magnetometric resistivity. Comparisons are made with analytical solutions, benchmark numerical solutions, analog experiments and field data. Although some calculations take too long to be practical as part of an inversion scheme, I suggest that modeling of this type will be useful for modeling novel techniques and for educational purposes.

  8. A general allometric and life-history model for cellular differentiation in the transition to multicellularity.

    PubMed

    Solari, Cristian A; Kessler, John O; Goldstein, Raymond E

    2013-03-01

    The transition from unicellular, to colonial, to larger multicellular organisms has benefits, costs, and requirements. Here we present a model inspired by the volvocine green algae that explains the dynamics involved in the unicellular-multicellular transition using life-history theory and allometry. We model the two fitness components (fecundity and viability) and compare the fitness of hypothetical colonies of different sizes with varying degrees of cellular differentiation to understand the general principles that underlie the evolution of multicellularity. We argue that germ-soma separation may have evolved to counteract the increasing costs and requirements of larger multicellular colonies. The model shows that the cost of investing in soma decreases with size. For lineages such as the Volvocales, as reproduction costs increase with size for undifferentiated colonies, soma specialization benefits the colony indirectly by decreasing such costs and directly by helping reproductive cells acquire resources for their metabolic needs. Germ specialization is favored once soma evolves and takes care of vegetative functions. To illustrate the model, we use some allometric relationships measured in Volvocales. Our analysis shows that the cost of reproducing an increasingly larger group has likely played an important role in the transition to multicellularity and cellular differentiation.

  9. Cellular Signaling Networks Function as Generalized Wiener-Kolmogorov Filters to Suppress Noise

    NASA Astrophysics Data System (ADS)

    Hinczewski, Michael; Thirumalai, D.

    2014-10-01

    Cellular signaling involves the transmission of environmental information through cascades of stochastic biochemical reactions, inevitably introducing noise that compromises signal fidelity. Each stage of the cascade often takes the form of a kinase-phosphatase push-pull network, a basic unit of signaling pathways whose malfunction is linked with a host of cancers. We show that this ubiquitous enzymatic network motif effectively behaves as a Wiener-Kolmogorov optimal noise filter. Using concepts from umbral calculus, we generalize the linear Wiener-Kolmogorov theory, originally introduced in the context of communication and control engineering, to take nonlinear signal transduction and discrete molecule populations into account. This allows us to derive rigorous constraints for efficient noise reduction in this biochemical system. Our mathematical formalism yields bounds on filter performance in cases important to cellular function—such as ultrasensitive response to stimuli. We highlight features of the system relevant for optimizing filter efficiency, encoded in a single, measurable, dimensionless parameter. Our theory, which describes noise control in a large class of signal transduction networks, is also useful both for the design of synthetic biochemical signaling pathways and the manipulation of pathways through experimental probes such as oscillatory input.

  10. IDSOLVER: A general purpose solver for nth-order integro-differential equations

    NASA Astrophysics Data System (ADS)

    Gelmi, Claudio A.; Jorquera, Héctor

    2014-01-01

    Many mathematical models of complex processes may be posed as integro-differential equations (IDE). Many numerical methods have been proposed for solving those equations, but most of them are ad hoc thus new equations have to be solved from scratch for translating the IDE into the framework of the specific method chosen. Furthermore, there is a paucity of general-purpose numerical solvers that free the user from additional tasks.

  11. Computational study on cortical spreading depression based on a generalized cellular automaton model

    NASA Astrophysics Data System (ADS)

    Chen, Shangbin; Hu, Lele; Li, Bing; Xu, Changcheng; Liu, Qian

    2009-02-01

    Cortical spreading depression (CSD) is an important neurophysiological phenomenon correlating with some neural disorders, such as migraine, cerebral ischemia and epilepsy. By now, we are still not clear about the mechanisms of CSD's initiation and propagation, also the relevance between CSD and those neural diseases. Nevertheless, characterization of CSD, especially the spatiotemporal evolution, will promote the understanding of the CSD's nature and mechanisms. Besides the previous experimental work on charactering the spatiotemporal evolution of CSD in rats by optical intrinsic signal imaging, a computational study based on a generalized cellular automaton (CA) model was proposed here. In the model, we exploited a generalized neighborhood connection rule: a central CA cell is related with a group of surrounding CA cells with different weight coefficients. By selecting special parameters, the generalized CA model could be transformed to the traditional CA models with von Neumann, Moore and hexagon neighborhood connection means. Hence, the new model covered several properties of CSD simulated in traditional CA models: 1) expanding from the origin site like a circular wave; 2) annihilation of two waves traveling in opposite directions after colliding; 3) wavefront of CSD breaking and recovering when and after encountering an obstacle. By setting different refractory period in the different CA lattice field, different connection coefficient in different direction within the defined neighborhood, inhomogeneous propagation of CSD was simulated with high fidelity. The computational results were analogous to the reported time-varying CSD waves by optical imaging. So, the generalized CA model would be useful to study CSD because of its intuitive appeal and computational efficiency.

  12. 77 FR 39885 - To Modify Duty-Free Treatment Under the Generalized System of Preferences, and for Other Purposes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-05

    ... Generalized System of Preferences, and for Other Purposes #0; #0; #0; Presidential Documents #0; #0; #0;#0... Generalized System of Preferences, and for Other Purposes By the President of the United States of America A... preferential tariff treatment under the Generalized System of Preferences (GSP) when imported from a...

  13. Movement analysis of upper limb during resistance training using general purpose robot arm "PA10"

    NASA Astrophysics Data System (ADS)

    Morita, Yoshifumi; Yamamoto, Takashi; Suzuki, Takahiro; Hirose, Akinori; Ukai, Hiroyuki; Matsui, Nobuyuki

    2005-12-01

    In this paper we perform movement analysis of an upper limb during resistance training. We selected sanding training, which is one type of resistance training for upper limbs widely performed in occupational therapy. Our final aims in the future are to quantitatively evaluate the therapeutic effect of upper limb motor function during training and to develop a new rehabilitation training support system. For these purposes, first of all we perform movement analysis using a conventional training tool. By measuring upper limb motion during the sanding training we perform feature abstraction. Next we perform movement analysis using the simulated sanding training system. This system is constructed using the general purpose robot arm "PA10". This system enables us to measure the force/torque exerted by subjects and to easily change the load of resistance. The control algorithm is based on impedance control. We found these features of the upper limb motion during the sanding training.

  14. General-Purpose Heat Source safety verification test series: SVT-1 through SVT-6

    SciTech Connect

    Pavone, D.; George, T.G.; Frantz, C.E.

    1985-06-01

    The General-Purpose Heat Source (GPHS) is a modular heat source that will supply energy for Radioisotope Thermoelectric Generators (RTGs) in space missions. The Safety Verification Tests (SVTs) are performed to assess the plutonia containment capability of heat source modules subjected to certain accident environments. This interim report described the GPHS module configuration, the test environment, and the response of the module components following simulated reentry and solid Earth impact. The specific test environment of these initial six tests results from failure of the booster rocket to place the spacecraft in a proper trajectory and subsequent reentry of the GPHS modules from Earth orbit. 36 figs.

  15. General-Purpose Heat Source safety verification test series: SVT-1 through SVT-6

    NASA Astrophysics Data System (ADS)

    Pavone, D.; George, T. G.; Frantz, C. E.

    1985-06-01

    The General-Purpose Heat Source (GPHS) is a modular heat source that will supply energy for Radioisotope Thermoelectric Generators (RTGs) in space missions. The Safety Verification Tests (SVTs) are performed to assess the plutonium containment capability of heat source modules subjected to certain accident environments. This interim report described the GPHS module configuration, the test environment, and the response of the module components following simulated reentry and solid Earth impact. The specific test environment of these initial six tests results from failure of the booster rocket to place the spacecraft in a proper trajectory and subsequent reentry of the GPHS modules from Earth orbit.

  16. A simplified, general-purpose deep-space ranging correlator design

    NASA Technical Reports Server (NTRS)

    Tausworthe, R. C.; Smith, J. R.

    1988-01-01

    A much-simplified, yet more general-purpose multi-channel deep-space ranging system correlator design that was used in past JPL spacecraft ranging systems is described. The method applies to detection of both single-component and multiple-component ranging codes, in either sequential (mu) or composite (pi) transmitted forms, and using either pseudonoise or square-wave components. Using this design, the Phobos Probe ranging system correlator computational complexity was reduced by over three orders of magnitude in multiply-and-add circuits and 45,000 bits of accumulator storage.

  17. General purpose pulse shape analysis for fast scintillators implemented in digital readout electronics

    NASA Astrophysics Data System (ADS)

    Asztalos, Stephen J.; Hennig, Wolfgang; Warburton, William K.

    2016-01-01

    Pulse shape discrimination applied to certain fast scintillators is usually performed offline. In sufficiently high-event rate environments data transfer and storage become problematic, which suggests a different analysis approach. In response, we have implemented a general purpose pulse shape analysis algorithm in the XIA Pixie-500 and Pixie-500 Express digital spectrometers. In this implementation waveforms are processed in real time, reducing the pulse characteristics to a few pulse shape analysis parameters and eliminating time-consuming waveform transfer and storage. We discuss implementation of these features, their advantages, necessary trade-offs and performance. Measurements from bench top and experimental setups using fast scintillators and XIA processors are presented.

  18. General-purpose heat source project and space nuclear safety fuels program. Progress report, February 1980

    SciTech Connect

    Maraman, W.J.

    1980-05-01

    This formal monthly report covers the studies related to the use of /sup 238/PuO/sub 2/ in radioisotopic power systems carried out for the Advanced Nuclear Systems and Projects Division of the Los Alamos Scientific Laboratory. The two programs involved are: General-Purpose Heat Source Development and Space Nuclear Safety and Fuels. Most of the studies discussed here are of a continuing nature. Results and conclusions described may change as the work continues. Published reference to the results cited in this report should not be made without the explicit permission of the person in charge of the work.

  19. GPHS (General Purpose Heat Source) uranium oxide encapsulations supporting satellite safety tests

    SciTech Connect

    Kanne, W.R.

    1989-04-24

    General Purpose Heat Source (GPHS) simulant-fueled capsules were assembled, welded, nondestructively examined, and shipped to Los Alamos National Laboratory (LANL) for satellite safety tests. Simulant-fueled iridium capsules contain depleted uranium oxide pellets that serve as a stand-in for plutonium-238 oxide pellets. Information on forty seven capsules prepared during 1987 and 1988 is recorded in this memorandum along with a description of the processes used for encapsulation and evaluation. LANL expects to use all capsules for destructive safety tests, which are under way. Test results so far have demonstrated excellent integrity of the Savannah River capsule welds. 10 refs., 5 figs., 3 tabs.

  20. General purpose software for efficient uncertainty management of large finite element models

    PubMed Central

    Patelli, Edoardo; Murat Panayirci, H.; Broggi, Matteo; Goller, Barbara; Beaurepaire, Pierre; Pradlwarter, Helmut J.; Schuëller, Gerhart I.

    2012-01-01

    The aim of this paper is to demonstrate that stochastic analyses can be performed on large and complex models within affordable costs. Stochastic analyses offer a much more realistic approach for analysis and design of components and systems although generally computationally demanding. Hence, resorting to efficient approaches and high performance computing is required in order to reduce the execution time. A general purpose software that provides an integration between deterministic solvers (i.e. finite element solvers), efficient algorithms for uncertainty management and high performance computing is presented. The software is intended for a wide range of applications, which includes optimization analysis, life-cycle management, reliability and risk analysis, fatigue and fractures simulation, robust design. The applicability of the proposed tools for practical applications is demonstrated by means of a number of case studies of industrial interest involving detailed models. PMID:22474398

  1. General purpose computational tools for simulation and analysis of medium-energy backscattering spectra

    NASA Astrophysics Data System (ADS)

    Weller, Robert A.

    1999-06-01

    This paper describes a suite of computational tools for general-purpose ion-solid calculations, which has been implemented in the platform-independent computational environment Mathematica®. Although originally developed for medium energy work (beam energies < 300 keV), they are suitable for general, classical, non-relativistic calculations. Routines are available for stopping power, Rutherford and Lenz-Jensen (screened) cross sections, sputtering yields, small-angle multiple scattering, and back-scattering-spectrum simulation and analysis. Also included are a full range of supporting functions, as well as easily accessible atomic mass and other data on all the stable isotopes in the periodic table. The functions use common calling protocols, recognize elements and isotopes by symbolic names and, wherever possible, return symbolic results for symbolic inputs, thereby facilitating further computation. A new paradigm for the representation of backscattering spectra is introduced.

  2. 77 FR 18899 - To Modify Duty-Free Treatment Under the Generalized System of Preferences and For Other Purposes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-29

    ... Treatment Under the Generalized System of Preferences and For Other Purposes By the President of the United... beneficiary developing country under the Generalized System of Preferences (GSP) if such country fails to...

  3. A general-purpose approach to computer-aided dynamic analysis of a flexible helicopter

    NASA Technical Reports Server (NTRS)

    Agrawal, Om P.

    1988-01-01

    A general purpose mathematical formulation is described for dynamic analysis of a helicopter consisting of flexible and/or rigid bodies that undergo large translations and rotations. Rigid body and elastic sets of generalized coordinates are used. The rigid body coordinates define the location and the orientation of a body coordinate frame (global frame) with respect to an inertial frame. The elastic coordinates are introduced using a finite element approach in order to model flexible components. The compatibility conditions between two adjacent elements in a flexible body are imposed using a Boolean matrix, whereas the compatibility conditions between two adjacent bodies are imposed using the Lagrange multiplier approach. Since the form of the constraint equations depends upon the type of kinematic joint and involves only the generalized coordinates of the two participating elements, then a library of constraint elements can be developed to impose the kinematic constraint in an automated fashion. For the body constraints, the Lagrange multipliers yield the reaction forces and torques of the bodies at the joints. The virtual work approach is used to derive the equations of motion, which are a system of differential and algebraic equations that are highly nonlinear. The formulation presented is general and is compared with hard-wired formulations commonly used in helicopter analysis.

  4. Operation of general purpose stepping motor controllers at the National Synchrotron Light Source

    SciTech Connect

    Stubblefield, F.W.

    1986-10-01

    A prototype and four copies of a general purpose subsystem for mechanical positioning of detectors, samples, and beam line optical elements which constitute experiments at the National Synchrotron Light Source facility of Brookhaven National Laboratory have been constructed and placed into operation. Construction of a sixth subsystem is nearing completion. The subsystems effect mechanical positioning by controlling a set of stepping motors and their associated position encoders. The units are general purpose in the sense that they receive commands over a standard 9600 baud asynchronous serial line compatible with the RS-232-C electrical signal standard, generate TTL-compatible streams of stepping pulses which can be used with a wide variety of stepping motors, and read back position values from a number of different types and models of position encoder. The basic structure of the motor controller subsystem will be briefly reviewed. Short descriptions of the positioning apparatus actuated at each of the test and experiment stations employing a motor control unit are given. Additions and enhancements to the subsystem made in response to problems indicated by actual operation of the four installed units are described in more detail.

  5. Operation of general purpose stepping motor controllers at the National Synchrotron Light Source

    SciTech Connect

    Stubblefield, F.W.

    1987-02-01

    A prototype and four copies of a general purpose subsystem for mechanical positioning of detectors, samples, and beam line optical elements which constitute experiments at the National Synchrotron Light Source facility of Brookhaven National Laboratory have been constructed and placed into operation. Construction of a sixth subsystem is nearing completion. The subsystems effect mechanical positioning by controlling a set of stepping motors and their associated position encoders. The units are general purpose in the sense that they receive commands over a standard 9600 baud asynchronous serial line compatible with the RS-232-C electrical signal standard, generate TTL-compatible streams of stepping pulses which can be used with a wide variety of stepping motors, and read back position values from a number of different types and models of position encoder. The basic structure of the motor controller subsystem is briefly reviewed. Short descriptions of the positioning apparatus actuated at each of the test and experiment stations employing a motor control unit are given. Additions and enhancements to the sub-system made in response to problems indicated by actual operation of the four installed units are described in more detail.

  6. Neural Networks for Computer Vision: A Framework for Specifications of a General Purpose Vision System

    NASA Astrophysics Data System (ADS)

    Skrzypek, Josef; Mesrobian, Edmond; Gungner, David J.

    1989-03-01

    The development of autonomous land vehicles (ALV) capable of operating in an unconstrained environment has proven to be a formidable research effort. The unpredictability of events in such an environment calls for the design of a robust perceptual system, an impossible task requiring the programming of a system bases on the expectation of future, unconstrained events. Hence, the need for a "general purpose" machine vision system that is capable of perceiving and understanding images in an unconstrained environment in real-time. The research undertaken at the UCLA Machine Perception Laboratory addresses this need by focusing on two specific issues: 1) the long term goals for machine vision research as a joint effort between the neurosciences and computer science; and 2) a framework for evaluating progress in machine vision. In the past, vision research has been carried out independently within different fields including neurosciences, psychology, computer science, and electrical engineering. Our interdisciplinary approach to vision research is based on the rigorous combination of computational neuroscience, as derived from neurophysiology and neuropsychology, with computer science and electrical engineering. The primary motivation behind our approach is that the human visual system is the only existing example of a "general purpose" vision system and using a neurally based computing substrate, it can complete all necessary visual tasks in real-time.

  7. General Purpose Data-Driven Online System Health Monitoring with Applications to Space Operations

    NASA Technical Reports Server (NTRS)

    Iverson, David L.; Spirkovska, Lilly; Schwabacher, Mark

    2010-01-01

    Modern space transportation and ground support system designs are becoming increasingly sophisticated and complex. Determining the health state of these systems using traditional parameter limit checking, or model-based or rule-based methods is becoming more difficult as the number of sensors and component interactions grows. Data-driven monitoring techniques have been developed to address these issues by analyzing system operations data to automatically characterize normal system behavior. System health can be monitored by comparing real-time operating data with these nominal characterizations, providing detection of anomalous data signatures indicative of system faults, failures, or precursors of significant failures. The Inductive Monitoring System (IMS) is a general purpose, data-driven system health monitoring software tool that has been successfully applied to several aerospace applications and is under evaluation for anomaly detection in vehicle and ground equipment for next generation launch systems. After an introduction to IMS application development, we discuss these NASA online monitoring applications, including the integration of IMS with complementary model-based and rule-based methods. Although the examples presented in this paper are from space operations applications, IMS is a general-purpose health-monitoring tool that is also applicable to power generation and transmission system monitoring.

  8. Construction of a generalized simulator for multi-cellular organisms and its application to SMAD signal transduction.

    PubMed

    Kyoda, K M; Muraki, M; Kitano, H

    2000-01-01

    In this paper, we report development of a generalized simulation system based on ordinary differential equations for multi-cellular organisms, and results of the analysis on a Smad signal transduction cascade. The simulator implements intra-cellular and extra-cellular molecular processes, such as protein diffusion, ligand-receptor reaction, biochemical reaction, and gene expression. It simulates the spatio-temporal patterning in various biological phenomena for the single and multi-cellular organisms. In order to demonstrate the usefulness of the simulator, we constructed a model of Drosophila's Smad signal transduction, which includes protein diffusion, biochemical reaction and gene expression. The results suggest that the presence of negative feedback mechanism in the Smad pathway functions to improve the frequency response of the cascade against changes in the signaling.

  9. 77 FR 405 - To Modify Duty-Free Treatment Under the Generalized System of Preferences and for Other Purposes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-04

    ... [FR Doc. 2012-00019 Filed 1-3-12; 11:15 am] Billing code 7020-02-C #0; ... Generalized System of Preferences and for Other Purposes Proclamation 8771--To Modify the Harmonized Tariff... the Generalized System of Preferences and for Other Purposes By the President of the United States...

  10. General purpose dynamic Monte Carlo with continuous energy for transient analysis

    SciTech Connect

    Sjenitzer, B. L.; Hoogenboom, J. E.

    2012-07-01

    For safety assessments transient analysis is an important tool. It can predict maximum temperatures during regular reactor operation or during an accident scenario. Despite the fact that this kind of analysis is very important, the state of the art still uses rather crude methods, like diffusion theory and point-kinetics. For reference calculations it is preferable to use the Monte Carlo method. In this paper the dynamic Monte Carlo method is implemented in the general purpose Monte Carlo code Tripoli4. Also, the method is extended for use with continuous energy. The first results of Dynamic Tripoli demonstrate that this kind of calculation is indeed accurate and the results are achieved in a reasonable amount of time. With the method implemented in Tripoli it is now possible to do an exact transient calculation in arbitrary geometry. (authors)

  11. Conceptual Trade Study of General Purpose Heat Source Powered Stirling Converter Configurations

    NASA Technical Reports Server (NTRS)

    Turpin, J. B.

    2007-01-01

    This Technical Manual describes a parametric study of general purpose heat source (GPHS) powered Stirling converter configurations. This study was performed in support of MSFC s efforts to establish the capability to perform non-nuclear system level testing and integration of radioisotope power systems. Six different GPHS stack configurations at a total of three different power levels (80, 250, and 500 W(sub e) were analyzed. The thermal profiles of the integrated GPHS modules (for each configuration) were calculated to determine maximum temperatures for comparison to allowable material limits. Temperature profiles for off-nominal power conditions were also assessed in order to better understand how power demands from the Stirling engine impact the performance of a given configuration.

  12. Fostering ontology alignment sharing: a general-purpose RDF mapping format.

    PubMed

    Anguita, Alberto; Escrich, Ana; Maojo, Victor

    2013-01-01

    RDF has established in the last years as the language for describing, publishing and sharing biomedical resources. Following this trend, a great amount of RDF-based data sources, as well as ontologies, have appeared. Using a common language as RDF has provided a unified syntactic for sharing resources, but the semantics remain as the main cause of heterogeneity, hampering data integration and homogenization efforts. To overcome this issue, ontology alignment based solutions have been typically used. However, alignment information is usually codified using ad-hoc formats. In this paper, we present a general purpose ontology mapping format, totally independent from the homogenization approach to be applied. The format is accompanied with a Java API that offers mapping construction and parsing features, as well as some basic algorithms for applying it to data translation solutions.

  13. GPACC program cost work breakdown structure-dictionary. General purpose aft cargo carrier study, volume 3

    NASA Technical Reports Server (NTRS)

    1985-01-01

    The results of detailed cost estimates and economic analysis performed on the updated Model 101 configuration of the general purpose Aft Cargo Carrier (ACC) are given. The objective of this economic analysis is to provide the National Aeronautics and Space Administration (NASA) with information on the economics of using the ACC on the Space Transportation System (STS). The detailed cost estimates for the ACC are presented by a work breakdown structure (WBS) to ensure that all elements of cost are considered in the economic analysis and related subsystem trades. Costs reported by WBS provide NASA with a basis for comparing competing designs and provide detailed cost information that can be used to forecast phase C/D planning for new projects or programs derived from preliminary conceptual design studies. The scope covers all STS and STS/ACC launch vehicle cost impacts for delivering payloads to a 160 NM low Earth orbit (LEO).

  14. THERMAL TESTING OF PROTOTYPE GENERAL PURPOSE FISSILE PACKAGES USING A FURNACE

    SciTech Connect

    Smith, A; Lawrence Gelder, L; Paul Blanton, P

    2007-02-16

    The 9977/9978 General Purpose Fissile Package (GPFP) was designed by SRNL to replace the DOT 6M Specification Package and ship Plutonium and Uranium metals and oxides. Urethane foam was used for the overpack to ensure the package would withstand the 10CFR71.73(c)(2) crush test, which is a severe test for drum-type packages. In addition, it was necessary to confirm that the urethane foam configuration provided adequate thermal protection for the containment vessel during the subsequent 10CFR71.73(c)(4) thermal test. Development tests were performed on early prototype test specimens of different diameter overpacks and a range of urethane foam densities. The thermal test was performed using an industrial furnace. Test results were used to optimize the selection of package diameter and foam density, and provided the basis for design enhancements incorporated into the final package design.

  15. A general purpose feature extractor for light detection and ranging data.

    PubMed

    Li, Yangming; Olson, Edwin B

    2010-01-01

    Feature extraction is a central step of processing Light Detection and Ranging (LIDAR) data. Existing detectors tend to exploit characteristics of specific environments: corners and lines from indoor (rectilinear) environments, and trees from outdoor environments. While these detectors work well in their intended environments, their performance in different environments can be poor. We describe a general purpose feature detector for both 2D and 3D LIDAR data that is applicable to virtually any environment. Our method adapts classic feature detection methods from the image processing literature, specifically the multi-scale Kanade-Tomasi corner detector. The resulting method is capable of identifying highly stable and repeatable features at a variety of spatial scales without knowledge of environment, and produces principled uncertainty estimates and corner descriptors at same time. We present results on both software simulation and standard datasets, including the 2D Victoria Park and Intel Research Center datasets, and the 3D MIT DARPA Urban Challenge dataset.

  16. Strong scaling of general-purpose molecular dynamics simulations on GPUs

    NASA Astrophysics Data System (ADS)

    Glaser, Jens; Nguyen, Trung Dac; Anderson, Joshua A.; Lui, Pak; Spiga, Filippo; Millan, Jaime A.; Morse, David C.; Glotzer, Sharon C.

    2015-07-01

    We describe a highly optimized implementation of MPI domain decomposition in a GPU-enabled, general-purpose molecular dynamics code, HOOMD-blue (Anderson and Glotzer, 2013). Our approach is inspired by a traditional CPU-based code, LAMMPS (Plimpton, 1995), but is implemented within a code that was designed for execution on GPUs from the start (Anderson et al., 2008). The software supports short-ranged pair force and bond force fields and achieves optimal GPU performance using an autotuning algorithm. We are able to demonstrate equivalent or superior scaling on up to 3375 GPUs in Lennard-Jones and dissipative particle dynamics (DPD) simulations of up to 108 million particles. GPUDirect RDMA capabilities in recent GPU generations provide better performance in full double precision calculations. For a representative polymer physics application, HOOMD-blue 1.0 provides an effective GPU vs. CPU node speed-up of 12.5 ×.

  17. General Purpose Graphics Processing Unit Based High-Rate Rice Decompression and Reed-Solomon Decoding.

    SciTech Connect

    Loughry, Thomas A.

    2015-02-01

    As the volume of data acquired by space-based sensors increases, mission data compression/decompression and forward error correction code processing performance must likewise scale. This competency development effort was explored using the General Purpose Graphics Processing Unit (GPGPU) to accomplish high-rate Rice Decompression and high-rate Reed-Solomon (RS) decoding at the satellite mission ground station. Each algorithm was implemented and benchmarked on a single GPGPU. Distributed processing across one to four GPGPUs was also investigated. The results show that the GPGPU has considerable potential for performing satellite communication Data Signal Processing, with three times or better performance improvements and up to ten times reduction in cost over custom hardware, at least in the case of Rice Decompression and Reed-Solomon Decoding.

  18. GPP user`s guide - a general-purpose postprocessor for wind turbine data analysis

    SciTech Connect

    Buhl, Jr, M L

    1995-01-01

    GPP (pronounced {open_quotes}jeep{close_quotes}) is a General-Purpose Postprocessor for wind turbine data analysis. The author, a member of the Wind Technology Division (WTD) of the National Renewable Energy Laboratory (NREL), developed GPP to postprocess test data and simulation predictions. GPP reads data into large arrays and allows the user to run many types of analyses on the data stored in memory. It runs on inexpensive computers common in the wind industry. One can even use it on a laptop in the field. The author wrote the program in such a way as to make it easy to add new types of analyses and to port it to many types of computers. Although GPP is very powerful and feature-rich, it is still very easy to learn and to use. Exhaustive error trapping prevents one from losing valuable work due to input errors. GPP will, hopefully, make a significant impact on engineering productivity in the wind industry.

  19. Comparison of future battery systems for application to general-purpose electric vehicles

    SciTech Connect

    O'Connell, L.G.

    1980-08-01

    The results are presented of a study to compare the aluminium/air battery as a general purpose automobile power source with those secondary batteries evaluated in a four year study entitled Energy Storage Systems for Automobile Propulsion. The results of this study were published in three interim reports, one each in 1977, 1978 and 1979. The final report is being published in 1980. The aluminum/air battery had not developed early enough to be included in the evaluation. Recent progress on this battery makes it important to compare it on a vehicle system basis to other possible future batteries. The analysis techniques used in the comparison were the same as for the four-year study.

  20. Modification of hot cells for general purpose heat source assembly at the Radioisotope Power Systems Facility

    NASA Astrophysics Data System (ADS)

    Carteret, B. A.

    1991-09-01

    Eight existing, unused hot cells currently are being modified for use in the Radioisotope Power Systems Facility (RPSF) to assemble Pu-238 fueled heat sources for radioisotope thermoelectric generators (RTGs). Four air atmosphere cells will be used for storage, decanning, and decontamination of the iridium-clad radioisotope fuel. The remaining four argon atmosphere cells will be used to assemble fuel and graphite components for production and packaging of general purpose heat source (GPHS) assembly modules, which provide heat to drive the thermoelectric conversion process in the generators. The hot cells will be equipped to perform remote and glovebox-type operations. They will provide shielding and contamination control measures to reduce worker radiation exposure to levels within current U.S. Department of Energy (DOE) guidelines. Designs emphasize the Westinghouse Hanford Company (Westinghouse Hanford) as low as reasonably achievable (ALARA) radiation protection policy.

  1. Modification of hot cells for general purpose heat source assembly at the radioisotope power systems facility

    NASA Astrophysics Data System (ADS)

    Carteret, Betty A.

    1992-01-01

    Eight existing, unused hot cells currently are being modified for use in the Radioisotope Power Systems Facility (RPSF) to assemble 238Pu-fueled heat sources for Radioisotope Thermoelectric Generators (RTGs). Four air atmosphere cells will be used for storage, decanning, and decontamination of the iridium-clad radioisotope fuel. The remaining four argon atmosphere cells will be used to assemble fuel and graphite components for production and packaging of general purpose heat source (GPHS) assembly modules, which provide heat to drive the thermoelectric conversion process in the generators. The hot cells will be equipped to perform remote and glovebox-type operations. They will provide shielding and contamination control measures to reduce worker radiation exposure to levels within current U.S. Department of Energy (DOE) guidelines. Designs emphasize the Westinghouse Hanford Company (Westinghouse Hanford) as low as reasonably achievable (ALARA) radiation protection policy.

  2. General-purpose heat source safety verification test series: SVT-11 through SVT-13

    SciTech Connect

    George, T.G.; Pavone, D.

    1986-05-01

    The General-Purpose Heat Source (GPHS) is a modular component of the radioisotope thermoelectric generator that will provide power for the Galileo and Ulysses (formerly ISPM) space missions. The GPHS provides power by transmitting the heat of /sup 238/Pu ..cap alpha..-decay to an array of thermoelectric elements. Because the possibility of an orbital abort always exists, the heat source was designed and constructed to minimize plutonia release in any accident environment. The Safety Verification Test (SVT) series was formulated to evaluate the effectiveness of GPHS plutonia containment after atmospheric reentry and Earth impact. The first two reports (covering SVT-1 through SVT-10) described the results of flat, side-on, and angular module impacts against steel targets at 54 m/s. This report describes flat-on module impacts against concrete and granite targets, at velocities equivalent to or higher than previous SVTs.

  3. General-purpose heat source safety verification test series: SVT-7 through SVT-10

    NASA Astrophysics Data System (ADS)

    George, T. G.; Pavone, D.

    1985-09-01

    The General-Purpose Heat Source (GPHS) is a modular component of the radioisotope thermoelectric generator that will supply power for the Galileo and Ulysses (formerly ISPM) space missions. The GPHS provides power by transmitting the heat of (238)PuO2 (ALPHA)-decay to an array of thermoelectric elements. Because the possibility of an orbital abort always exists, the heat source was designed and constructed to minimize plutonia release in any accident environment. The Safety Verification Test (SVT) series was formulated to evaluate the effectiveness of GPHS plutonia containment after atmospheric reentry and Earth impact. The first report (covering SVT-1 through SVT-6) described the results of flat and side-on module impacts. This report describes module impacts at angles of 15(0) and 30(0).

  4. General-Purpose Heat Source Safety Verification Test series: SVT-7 through SVT-10

    SciTech Connect

    George, T.G.; Pavone, D.

    1985-09-01

    The General-Purpose Heat Source (GPHS) is a modular component of the radioisotope thermoelectric generator that will supply power for the Galileo and Ulysses (formerly ISPM) space missions. The GPHS provides power by transmitting the heat of /sup 238/PuO/sub 2/ ..cap alpha..-decay to an array of thermoelectric elements. Because the possibility of an orbital abort always exists, the heat source was designed and constructed to minimize plutonia release in any accident environment. The Safety Verification Test (SVT) series was formulated to evaluate the effectiveness of GPHS plutonia containment after atmospheric reentry and Earth impact. The first report (covering SVT-1 through SVT-6) described the results of flat and side-on module impacts. This report describes module impacts at angles of 15/sup 0/ and 30/sup 0/.

  5. General-purpose heat source development: Safety test program. Postimpact evaluation, design iteration test 1

    NASA Astrophysics Data System (ADS)

    Schonfeld, F. W.

    1984-04-01

    The general purpose heat source (GPHS) provides power for space missions by transmitting the heat of (238)PuO decay to thermoelectric elements. Because of the inevitable return of certain missions, the heat source must be designed and constructed to survive reentry and Earth impact. The Design Iteration Test (DIT) series is part of an ongoing impact test program. The first DIT used a full GPHS module containing two graphite impact shells (GISs); each GIS contained two iridium (0.3 wt%) capsules filled with (238)PuO. It was impacted at 57 m/s and 930 C. All four fuel capsules survived and none was breached. However, serious cracking of the iridium alloy capsules was found; some cracks extended through approx. 70% of the wall thickness. Postimpact analyses of the unit are described with emphasis on weld structure and performance.

  6. General-purpose heat source safety verification test series: SVT-11 through SVT-13

    NASA Astrophysics Data System (ADS)

    George, T. G.; Pavone, D.

    1986-05-01

    The General-Purpose Heat Source (GPHS) is a modular component of the radioisotope thermoelectric generator that will provide power for the Galileo and Ulysses (formerly ISPM) space missions. The GPHS provides power by transmitting the heat of Pu -decay to an array of thermoelectric elements. Because the possibility of an orbital abort always exists, the heat source was designed and constructed to minimize plutonia release in any accident environment. The Safety Verification Test (SVT) series was formulated to evaluate the effectiveness of GPHS plutonia containment after atmospheric reentry and Earth impact. The first two reports (covering SVT-1 through SVT-10) described the results of flat, side-on, and angular module impacts against steel targets at 54 m/s. This report describes flat-on module impacts against concrete and granite targets, at velocities equivalent to or higher than previous SVTs.

  7. STARS: An integrated general-purpose finite element structural, aeroelastic, and aeroservoelastic analysis computer program

    NASA Technical Reports Server (NTRS)

    Gupta, Kajal K.

    1991-01-01

    The details of an integrated general-purpose finite element structural analysis computer program which is also capable of solving complex multidisciplinary problems is presented. Thus, the SOLIDS module of the program possesses an extensive finite element library suitable for modeling most practical problems and is capable of solving statics, vibration, buckling, and dynamic response problems of complex structures, including spinning ones. The aerodynamic module, AERO, enables computation of unsteady aerodynamic forces for both subsonic and supersonic flow for subsequent flutter and divergence analysis of the structure. The associated aeroservoelastic analysis module, ASE, effects aero-structural-control stability analysis yielding frequency responses as well as damping characteristics of the structure. The program is written in standard FORTRAN to run on a wide variety of computers. Extensive graphics, preprocessing, and postprocessing routines are also available pertaining to a number of terminals.

  8. Generic functional requirements for a NASA general-purpose data base management system

    NASA Technical Reports Server (NTRS)

    Lohman, G. M.

    1981-01-01

    Generic functional requirements for a general-purpose, multi-mission data base management system (DBMS) for application to remotely sensed scientific data bases are detailed. The motivation for utilizing DBMS technology in this environment is explained. The major requirements include: (1) a DBMS for scientific observational data; (2) a multi-mission capability; (3) user-friendly; (4) extensive and integrated information about data; (5) robust languages for defining data structures and formats; (6) scientific data types and structures; (7) flexible physical access mechanisms; (8) ways of representing spatial relationships; (9) a high level nonprocedural interactive query and data manipulation language; (10) data base maintenance utilities; (11) high rate input/output and large data volume storage; and adaptability to a distributed data base and/or data base machine configuration. Detailed functions are specified in a top-down hierarchic fashion. Implementation, performance, and support requirements are also given.

  9. A general purpose feature extractor for light detection and ranging data.

    PubMed

    Li, Yangming; Olson, Edwin B

    2010-01-01

    Feature extraction is a central step of processing Light Detection and Ranging (LIDAR) data. Existing detectors tend to exploit characteristics of specific environments: corners and lines from indoor (rectilinear) environments, and trees from outdoor environments. While these detectors work well in their intended environments, their performance in different environments can be poor. We describe a general purpose feature detector for both 2D and 3D LIDAR data that is applicable to virtually any environment. Our method adapts classic feature detection methods from the image processing literature, specifically the multi-scale Kanade-Tomasi corner detector. The resulting method is capable of identifying highly stable and repeatable features at a variety of spatial scales without knowledge of environment, and produces principled uncertainty estimates and corner descriptors at same time. We present results on both software simulation and standard datasets, including the 2D Victoria Park and Intel Research Center datasets, and the 3D MIT DARPA Urban Challenge dataset. PMID:22163474

  10. An evaluation of alternate production methods for Pu-238 general purpose heat source pellets

    SciTech Connect

    Mark Borland; Steve Frank

    2009-06-01

    For the past half century, the National Aeronautics and Space Administration (NASA) has used Radioisotope Thermoelectric Generators (RTG) to power deep space satellites. Fabricating heat sources for RTGs, specifically General Purpose Heat Sources (GPHSs), has remained essentially unchanged since their development in the 1970s. Meanwhile, 30 years of technological advancements have been made in the applicable fields of chemistry, manufacturing and control systems. This paper evaluates alternative processes that could be used to produce Pu 238 fueled heat sources. Specifically, this paper discusses the production of the plutonium-oxide granules, which are the input stream to the ceramic pressing and sintering processes. Alternate chemical processes are compared to current methods to determine if alternative fabrication processes could reduce the hazards, especially the production of respirable fines, while producing an equivalent GPHS product.

  11. Simrank: Rapid and sensitive general-purpose k-mer search tool

    SciTech Connect

    DeSantis, T.Z.; Keller, K.; Karaoz, U.; Alekseyenko, A.V; Singh, N.N.S.; Brodie, E.L; Pei, Z.; Andersen, G.L; Larsen, N.

    2011-04-01

    Terabyte-scale collections of string-encoded data are expected from consortia efforts such as the Human Microbiome Project (http://nihroadmap.nih.gov/hmp). Intra- and inter-project data similarity searches are enabled by rapid k-mer matching strategies. Software applications for sequence database partitioning, guide tree estimation, molecular classification and alignment acceleration have benefited from embedded k-mer searches as sub-routines. However, a rapid, general-purpose, open-source, flexible, stand-alone k-mer tool has not been available. Here we present a stand-alone utility, Simrank, which allows users to rapidly identify database strings the most similar to query strings. Performance testing of Simrank and related tools against DNA, RNA, protein and human-languages found Simrank 10X to 928X faster depending on the dataset. Simrank provides molecular ecologists with a high-throughput, open source choice for comparing large sequence sets to find similarity.

  12. A general purpose subroutine for fast fourier transform on a distributed memory parallel machine

    NASA Technical Reports Server (NTRS)

    Dubey, A.; Zubair, M.; Grosch, C. E.

    1992-01-01

    One issue which is central in developing a general purpose Fast Fourier Transform (FFT) subroutine on a distributed memory parallel machine is the data distribution. It is possible that different users would like to use the FFT routine with different data distributions. Thus, there is a need to design FFT schemes on distributed memory parallel machines which can support a variety of data distributions. An FFT implementation on a distributed memory parallel machine which works for a number of data distributions commonly encountered in scientific applications is presented. The problem of rearranging the data after computing the FFT is also addressed. The performance of the implementation on a distributed memory parallel machine Intel iPSC/860 is evaluated.

  13. GPP user's guide: A general-purpose postprocessor for wind turbine data analysis

    NASA Astrophysics Data System (ADS)

    Buhl, M. L., Jr.

    1995-01-01

    GPP is a General-Purpose Postprocessor for wind turbine data analysis. The author, a member of the Wind Technology Division (WTD) of the National Renewable Energy Laboratory (NREL), developed GPP to postprocess test data and simulation predictions. GPP reads data into large arrays and allows the user to run many types of analyses on the data stored in memory. It runs on inexpensive computers common in the wind industry. One can even use it on a laptop in the field. The author wrote the program in such a way as to make it easy to add new types of analyses and to port it to many types of computers. Although GPP is very powerful and feature-rich, it is still very easy to learn and to use. Exhaustive error trapping prevents one from losing valuable work due to input errors. GPP will, hopefully, make a significant impact on engineering productivity in the wind industry.

  14. A fast general-purpose clustering algorithm based on FPGAs for high-throughput data processing

    NASA Astrophysics Data System (ADS)

    Annovi, A.; Beretta, M.

    2010-05-01

    We present a fast general-purpose algorithm for high-throughput clustering of data "with a two-dimensional organization". The algorithm is designed to be implemented with FPGAs or custom electronics. The key feature is a processing time that scales linearly with the amount of data to be processed. This means that clustering can be performed in pipeline with the readout, without suffering from combinatorial delays due to looping multiple times through all the data. This feature makes this algorithm especially well suited for problems where the data have high density, e.g. in the case of tracking devices working under high-luminosity condition such as those of LHC or super-LHC. The algorithm is organized in two steps: the first step (core) clusters the data; the second step analyzes each cluster of data to extract the desired information. The current algorithm is developed as a clustering device for modern high-energy physics pixel detectors. However, the algorithm has much broader field of applications. In fact, its core does not specifically rely on the kind of data or detector it is working for, while the second step can and should be tailored for a given application. For example, in case of spatial measurement with silicon pixel detectors, the second step performs center of charge calculation. Applications can thus be foreseen to other detectors and other scientific fields ranging from HEP calorimeters to medical imaging. An additional advantage of this two steps approach is that the typical clustering related calculations (second step) are separated from the combinatorial complications of clustering. This separation simplifies the design of the second step and it enables it to perform sophisticated calculations achieving offline quality in online applications. The algorithm is general purpose in the sense that only minimal assumptions on the kind of clustering to be performed are made.

  15. Design of the SLAC RCE Platform: A General Purpose ATCA Based Data Acquisition System

    SciTech Connect

    Herbst, R.; Claus, R.; Freytag, M.; Haller, G.; Huffer, M.; Maldonado, S.; Nishimura, K.; O'Grady, C.; Panetta, J.; Perazzo, A.; Reese, B.; Ruckman, L.; Thayer, J. G.; Weaver, M.

    2015-01-23

    The SLAC RCE platform is a general purpose clustered data acquisition system implemented on a custom ATCA compliant blade, called the Cluster On Board (COB). The core of the system is the Reconfigurable Cluster Element (RCE), which is a system-on-chip design based upon the Xilinx Zynq family of FPGAs, mounted on custom COB daughter-boards. The Zynq architecture couples a dual core ARM Cortex A9 based processor with a high performance 28nm FPGA. The RCE has 12 external general purpose bi-directional high speed links, each supporting serial rates of up to 12Gbps. 8 RCE nodes are included on a COB, each with a 10Gbps connection to an on-board 24-port Ethernet switch integrated circuit. The COB is designed to be used with a standard full-mesh ATCA backplane allowing multiple RCE nodes to be tightly interconnected with minimal interconnect latency. Multiple shelves can be clustered using the front panel 10-gbps connections. The COB also supports local and inter-blade timing and trigger distribution. An experiment specific Rear Transition Module adapts the 96 high speed serial links to specific experiments and allows an experiment-specific timing and busy feedback connection. This coupling of processors with a high performance FPGA fabric in a low latency, multiple node cluster allows high speed data processing that can be easily adapted to any physics experiment. RTEMS and Linux are both ported to the module. The RCE has been used or is the baseline for several current and proposed experiments (LCLS, HPS, LSST, ATLAS-CSC, LBNE, DarkSide, ILC-SiD, etc).

  16. BCI2000: a general-purpose brain-computer interface (BCI) system.

    PubMed

    Schalk, Gerwin; McFarland, Dennis J; Hinterberger, Thilo; Birbaumer, Niels; Wolpaw, Jonathan R

    2004-06-01

    Many laboratories have begun to develop brain-computer interface (BCI) systems that provide communication and control capabilities to people with severe motor disabilities. Further progress and realization of practical applications depends on systematic evaluations and comparisons of different brain signals, recording methods, processing algorithms, output formats, and operating protocols. However, the typical BCI system is designed specifically for one particular BCI method and is, therefore, not suited to the systematic studies that are essential for continued progress. In response to this problem, we have developed a documented general-purpose BCI research and development platform called BCI2000. BCI2000 can incorporate alone or in combination any brain signals, signal processing methods, output devices, and operating protocols. This report is intended to describe to investigators, biomedical engineers, and computer scientists the concepts that the BC12000 system is based upon and gives examples of successful BCI implementations using this system. To date, we have used BCI2000 to create BCI systems for a variety of brain signals, processing methods, and applications. The data show that these systems function well in online operation and that BCI2000 satisfies the stringent real-time requirements of BCI systems. By substantially reducing labor and cost, BCI2000 facilitates the implementation of different BCI systems and other psychophysiological experiments. It is available with full documentation and free of charge for research or educational purposes and is currently being used in a variety of studies by many research groups. PMID:15188875

  17. Dielectrophoresis-Based Sample Handling in General-Purpose Programmable Diagnostic Instruments

    PubMed Central

    Gascoyne, Peter R. C.; Vykoukal, Jody V.

    2009-01-01

    As the molecular origins of disease are better understood, the need for affordable, rapid, and automated technologies that enable microscale molecular diagnostics has become apparent. Widespread use of microsystems that perform sample preparation and molecular analysis could ensure that the benefits of new biomedical discoveries are realized by a maximum number of people, even those in environments lacking any infrastructure. While progress has been made in developing miniaturized diagnostic systems, samples are generally processed off-device using labor-intensive and time-consuming traditional sample preparation methods. We present the concept of an integrated programmable general-purpose sample analysis processor (GSAP) architecture where raw samples are routed to separation and analysis functional blocks contained within a single device. Several dielectrophoresis-based methods that could serve as the foundation for building GSAP functional blocks are reviewed including methods for cell and particle sorting, cell focusing, cell ac impedance analysis, cell lysis, and the manipulation of molecules and reagent droplets. PMID:19684877

  18. ABAQUS-EPGEN: a general-purpose finite-element code. Volume 4. Systems manual

    SciTech Connect

    Hibbitt, H.D.; Karlsson, B.I.; Sorensen, E.P.

    1985-06-01

    This document is the Systems Manual for ABAQUS/EPGEN, a general purpose finite element computer program designed specifically to serve advanced structural analysis needs. ABAQUS/EPGEN is a large, modular, software system, made up of libraries of finite elements, constitutive models, arithmetic routines, and executive level routines that control the flow through the program to provide various analysis procedures. ABAQUS has extensive data files which are managed independently from the engineering/modeling code. The program is written in FORTRAN 77, with additional conventions within the language to ensure that the code is readily portable across different computers and operating systems. This includes support of fully single and fully double precision versions. This manual documents the system design of the code, including detailed descriptions of data file contents, and dictionaries of subroutines and common blocks. This outline can help programmers and development engineers understand the structure of the code and its use on different computers and operating systems. The highly sophisticated, nonlinear computer code supports advanced structural analyses for nuclear and fossil fuel power plant designs. The ABAQUS-EPGEN code analyzes such general nonlinear phenomena as fluid-structure interactions, reinforced concrete behavior, thermal stress, fracture mechanics, and high-temperature structural behavior. 18 refs.

  19. The PennBMBI: Design of a General Purpose Wireless Brain-Machine-Brain Interface System.

    PubMed

    Liu, Xilin; Zhang, Milin; Subei, Basheer; Richardson, Andrew G; Lucas, Timothy H; Van der Spiegel, Jan

    2015-04-01

    In this paper, a general purpose wireless Brain-Machine-Brain Interface (BMBI) system is presented. The system integrates four battery-powered wireless devices for the implementation of a closed-loop sensorimotor neural interface, including a neural signal analyzer, a neural stimulator, a body-area sensor node and a graphic user interface implemented on the PC end. The neural signal analyzer features a four channel analog front-end with configurable bandpass filter, gain stage, digitization resolution, and sampling rate. The target frequency band is configurable from EEG to single unit activity. A noise floor of 4.69 μVrms is achieved over a bandwidth from 0.05 Hz to 6 kHz. Digital filtering, neural feature extraction, spike detection, sensing-stimulating modulation, and compressed sensing measurement are realized in a central processing unit integrated in the analyzer. A flash memory card is also integrated in the analyzer. A 2-channel neural stimulator with a compliance voltage up to ± 12 V is included. The stimulator is capable of delivering unipolar or bipolar, charge-balanced current pulses with programmable pulse shape, amplitude, width, pulse train frequency and latency. A multi-functional sensor node, including an accelerometer, a temperature sensor, a flexiforce sensor and a general sensor extension port has been designed. A computer interface is designed to monitor, control and configure all aforementioned devices via a wireless link, according to a custom designed communication protocol. Wireless closed-loop operation between the sensory devices, neural stimulator, and neural signal analyzer can be configured. The proposed system was designed to link two sites in the brain, bridging the brain and external hardware, as well as creating new sensory and motor pathways for clinical practice. Bench test and in vivo experiments are performed to verify the functions and performances of the system.

  20. The PennBMBI: Design of a General Purpose Wireless Brain-Machine-Brain Interface System.

    PubMed

    Liu, Xilin; Zhang, Milin; Subei, Basheer; Richardson, Andrew G; Lucas, Timothy H; Van der Spiegel, Jan

    2015-04-01

    In this paper, a general purpose wireless Brain-Machine-Brain Interface (BMBI) system is presented. The system integrates four battery-powered wireless devices for the implementation of a closed-loop sensorimotor neural interface, including a neural signal analyzer, a neural stimulator, a body-area sensor node and a graphic user interface implemented on the PC end. The neural signal analyzer features a four channel analog front-end with configurable bandpass filter, gain stage, digitization resolution, and sampling rate. The target frequency band is configurable from EEG to single unit activity. A noise floor of 4.69 μVrms is achieved over a bandwidth from 0.05 Hz to 6 kHz. Digital filtering, neural feature extraction, spike detection, sensing-stimulating modulation, and compressed sensing measurement are realized in a central processing unit integrated in the analyzer. A flash memory card is also integrated in the analyzer. A 2-channel neural stimulator with a compliance voltage up to ± 12 V is included. The stimulator is capable of delivering unipolar or bipolar, charge-balanced current pulses with programmable pulse shape, amplitude, width, pulse train frequency and latency. A multi-functional sensor node, including an accelerometer, a temperature sensor, a flexiforce sensor and a general sensor extension port has been designed. A computer interface is designed to monitor, control and configure all aforementioned devices via a wireless link, according to a custom designed communication protocol. Wireless closed-loop operation between the sensory devices, neural stimulator, and neural signal analyzer can be configured. The proposed system was designed to link two sites in the brain, bridging the brain and external hardware, as well as creating new sensory and motor pathways for clinical practice. Bench test and in vivo experiments are performed to verify the functions and performances of the system. PMID:25769171

  1. General-Purpose Heat Source Development: Safety Verification Test Program. Flyer plate test series

    SciTech Connect

    Cull, T.A.; Pavone, D.

    1986-09-01

    The General-Purpose Heat Source (GPHS) is a modular component of a radioisotope thermoelectric generator (RTG) that will provide electric power for space missions. The initial RTG applications will be for the NASA Galileo and the ESA Ulysses missions. Each of the 18 GPHS modules in an RTG contains four /sup 238/PuO/sub 2/-fueled clads and generates 250 W/sub (t)/. A series of Safety Verification Tests (SVTs) has been conducted to assess the ability of the GPHS fueled clads to contain the plutonia in accident environments. Because a launch pad or postlaunch explosion of the Space Transportation System Vehicle (space shuttle) is one conceivable accident, the SVT plan included a series of tests to simulate the fragment environment that the RTG and GPHS modules would experience in such an event. These tests deal specifically with the flat-on collision of flyer-plate-type fragments with bare, simulant-fueled (depleted UO/sub 2/) clads. Results of these tests suggest that the fueled clad is only minimally breached by collision with 3.53-mm-thick flyer-plate-type fragments of space shuttle alloy at velocities up to 1170 m/s. However, collision of a 38.1-mm-thick plate with a bare GPHS clad, at a velocity of 270 m/s, results in a total release of fuel.

  2. A general purpose model for the condensed phases of water: TIP4P/2005.

    PubMed

    Abascal, J L F; Vega, C

    2005-12-15

    A potential model intended to be a general purpose model for the condensed phases of water is presented. TIP4P/2005 is a rigid four site model which consists of three fixed point charges and one Lennard-Jones center. The parametrization has been based on a fit of the temperature of maximum density (indirectly estimated from the melting point of hexagonal ice), the stability of several ice polymorphs and other commonly used target quantities. The calculated properties include a variety of thermodynamic properties of the liquid and solid phases, the phase diagram involving condensed phases, properties at melting and vaporization, dielectric constant, pair distribution function, and self-diffusion coefficient. These properties cover a temperature range from 123 to 573 K and pressures up to 40,000 bar. The model gives an impressive performance for this variety of properties and thermodynamic conditions. For example, it gives excellent predictions for the densities at 1 bar with a maximum density at 278 K and an averaged difference with experiment of 7 x 10(-4) g/cm3.

  3. Application of NASA General-Purpose Solver to Large-Scale Computations in Aeroacoustics

    NASA Technical Reports Server (NTRS)

    Watson, Willie R.; Storaasli, Olaf O.

    2004-01-01

    Of several iterative and direct equation solvers evaluated previously for computations in aeroacoustics, the most promising was the NASA-developed General-Purpose Solver (winner of NASA's 1999 software of the year award). This paper presents detailed, single-processor statistics of the performance of this solver, which has been tailored and optimized for large-scale aeroacoustic computations. The statistics, compiled using an SGI ORIGIN 2000 computer with 12 Gb available memory (RAM) and eight available processors, are the central processing unit time, RAM requirements, and solution error. The equation solver is capable of solving 10 thousand complex unknowns in as little as 0.01 sec using 0.02 Gb RAM, and 8.4 million complex unknowns in slightly less than 3 hours using all 12 Gb. This latter solution is the largest aeroacoustics problem solved to date with this technique. The study was unable to detect any noticeable error in the solution, since noise levels predicted from these solution vectors are in excellent agreement with the noise levels computed from the exact solution. The equation solver provides a means for obtaining numerical solutions to aeroacoustics problems in three dimensions.

  4. General-Purpose Expression of Structural Connectivity in the Parallel Solution Scheme and Its Application

    NASA Astrophysics Data System (ADS)

    Isobe, Daigoro; Yagi, Atsushi; Sato, Shunsuke

    In this paper, an algorithm for the general-purpose expression of structural connectivity is developed and implemented into the parallel solution scheme, which was previously proposed and successively applied to the feed-forward control of link mechanisms under various boundary conditions. The parallel solution scheme calculates the inverse dynamics of link systems by using a matrix-form equation separated into individual terms of different parameters. Therefore, the connectivity of link members can be expressed explicitly by one of the matrices, the member length matrix. Generated forces for the control can also be considered, without using any Jacobian matrices, simply by adding the values into one of the components in the equation, the vector related to nodal forces. We describe the forming process of the member length matrix and verify the validity of the calculated torque values, by presenting simple numerical results and experimental results for a structure-varying link system. We also perform a force control experiment on a quick motion, two-arm link system holding an object, where both generated forces and dynamical effects should be considered. Numerical and experimental results show the validity and the extensive ability of the scheme.

  5. Practical Implementation of Prestack Kirchhoff Time Migration on a General Purpose Graphics Processing Unit

    NASA Astrophysics Data System (ADS)

    Liu, Guofeng; Li, Chun

    2016-08-01

    In this study, we present a practical implementation of prestack Kirchhoff time migration (PSTM) on a general purpose graphic processing unit. First, we consider the three main optimizations of the PSTM GPU code, i.e., designing a configuration based on a reasonable execution, using the texture memory for velocity interpolation, and the application of an intrinsic function in device code. This approach can achieve a speedup of nearly 45 times on a NVIDIA GTX 680 GPU compared with CPU code when a larger imaging space is used, where the PSTM output is a common reflection point that is gathered as I[nx][ny][nh][nt] in matrix format. However, this method requires more memory space so the limited imaging space cannot fully exploit the GPU sources. To overcome this problem, we designed a PSTM scheme with multi-GPUs for imaging different seismic data on different GPUs using an offset value. This process can achieve the peak speedup of GPU PSTM code and it greatly increases the efficiency of the calculations, but without changing the imaging result.

  6. Evaluation and characterization of General Purpose Heat Source girth welds for the Cassini mission

    SciTech Connect

    Lynch, C.M.; Moniz, P.F.; Reimus, M.A.H.

    1998-12-31

    General Purpose Heat Sources (GPHSs) are components of Radioisotopic thermoelectric Generators (RTGs) which provide electric power for deep space missions. Each GPHS consists of a {sup 238}Pu oxide ceramic pellet encapsulated in a welded iridium alloy shell which forms a protective barrier against the release of plutonia in the unlikely event of a launch-pad failure or reentry incident. GPHS fueled clad girth weld flaw detection was paramount to ensuring this safety function, and was accomplished using both destructive and non-destructive evaluation techniques. The first girth weld produced from each welding campaign was metallographically examined for flaws such as incomplete weld penetration, cracks, or porosity which would render a GPHS unacceptable for flight applications. After an acceptable example weld was produced, the subsequently welded heat sources were evaluated non-destructively for flaws using ultrasonic immersion testing. Selected heat sources which failed ultrasonic testing would be radiographed, and/or, destructively evaluated to further characterize and document anomalous indications. Metallography was also performed on impacted heat sources to determine the condition of the welds.

  7. General-Purpose Heat Source development: safety test program. Postimpact evaluation, Design Iteration Test 2

    SciTech Connect

    Schonfeld, F.W.; George, T.G.

    1984-06-01

    The General-Purpose Heat Source (GPHS) provides power for space missions by transmitting the heat of /sup 238/PuO/sub 2/ decay to thermoelectric elements. Because of the inevitable return of certain missions, the heat source must be Designed and constructed to survive both re-entry and Earth impact. The Design Iteration Test (DIT) series is part of an ongoing test program. In the first Design Iteration Test (DIT-1), a full GPHS module ontaining four iridium-alloy capsules loaded with /sup 238/PuO/sub 2/ was impacted at 57 m/s and 930/sup 0/C. All four capsules survived and none was breached. The capsules used in DIT-1 were loaded and welded at Los Alamos. The second Design Iteration Test (DIT-2) also used a full GPHS module and was impacted at 58 m/s and 930/sup 0/C. The four iridium-alloy capsules used in this test were loaded and welded at the Savannah River Plant (SRP). Postimpact examination revealed that two capsules had survived and two capsules had breached; a small quantity (approx. = 50 ..mu..g) of /sup 238/PuO/sub 2/ was released from the breached capsules. Internal cracking similar to that observed in the DIT-1 capsules was evident in all four of the DIT-2 capsules. Postimpact analyses of the units are described with emphasis on weld structure and performance.

  8. General-purpose heat source development: Safety test program. Postimpact evaluation, design iteration test 5

    NASA Astrophysics Data System (ADS)

    George, T. G.; Schonfeld, F. W.

    1984-12-01

    The general-purpose heat source (GPHS) provides power for space missions by transmitting the heat of Pu-238 decay to thermoelectric elements. Because of the inevitable return of certain aborted missions, the heat source must be designed and constructed to survive both reentry and Earth impact. The design iteration test (DIT) series is part of an ongoing impact test program. The DIT-5 was designed to compare the impact response of a GPHS fueled clad that was welded with a four-pole arc oscillator with the impact response of a clad welded with a two-pole oscillator. In DIT-5 a partial GPHS module containing two fueled clads was impacted at 60.5 m/s and 930 C. The fuel capsules were severly deformed by the impact; both clads breached. The capsule welded with a four-pole oscillator failed extensively. Neither failure was related to the welding technique. Postimpact analyses of the test components are described, with emphasis on microstructure and impact response.

  9. Design evolution and verification of the general-purpose heat source

    SciTech Connect

    Schock, A

    1980-01-01

    The General-Purpose Heat Source (GPHS) is a radioisotope heat source for use in space power systems. It employs a modular design, to make it adaptable to a wide range of energy conversion systems and power levels. Each 250 W module is completely autonomous, with its own passive safety provisions to prevent fuel release under all abort modes, including atmospheric reentry and earth impact. Prior development tests had demonstrated good impact survival as long as the iridium fuel capsules retained their ductility. This requires high impact temperatures, typically above 900/sup 0/C and reasonably fine grain size, which in turn requires avoidance of excessive operating temperatures and reentry temperatures. These three requirements - on operating, reentry, and impact temperatures - are in mutual conflict, since thermal design changes to improve any one of these temperatures tend to worsen one or both of the others. This conflict creates a difficult design problem, which for a time threatened the success of the program. The present paper describes how this problem was overcome by successive design revisions, supplemented by thermal analyses and confirmatory vibration and impact tests; and how this may be achieved while raising the specific power of the GPHS to 83 W/lb, a 50% improvement over previously flown radioisotope heat sources.

  10. General-Purpose Heat Source Development: safety test program. Postimpact evaluation, Design Iteration Test 4

    SciTech Connect

    George, T.G.; Schonfeld, F.W.

    1984-12-01

    The General-Purpose Heat Source (GPHS) provides power for space missions by transmitting the heat of /sup 238/Pu decay to thermoelectric elements. Because of the inevitable return of certain aborted missions, the heat source must be designed and constructed to survive both re-entry and Earth impact. The Design Iteration Test (DIT) series is part of an ongoing test program. The fourth test (DIT-4) was designed to evaluate the effect on impact behavior of changing the procedure used at the Mound Facility (MF) to remove surface defects from drawn cups. The change involved switching from a manual abrasion technique to a motorized, rubber-bonded abrasive wheel. In DIT-4 a partial GPHS module containing two fueled clads (one cleaned manually, and one cleaned with an abrasive wheel) was impacted at a velocity of 58 m/s and a temperature of 930/sup 0/C. Both capsules were severely deformed by the impact and contained large internal cracks. Although the manually cleaned capsule breached, the breaching crack was only 2 ..mu..m wide and released negligible amounts of fuel. There did not appear to be any correlation between cleaning method and capsule performance. Postimpact analyses of the DIT-4 test components are described with emphasis on microstructure and impact response.

  11. General-Purpose Heat Source Development: safety test program. Postimpact evaluation, Design Iteration Test 5

    SciTech Connect

    George, T.G.; Schonfeld, F.W.

    1984-12-01

    The General-Purpose Heat Source (GPHS) provides power for space missions by transmitting the heat of /sup 238/Pu decay to thermoelectric elements. Because of the inevitable return of certain aborted missions, the heat source must be designed and constructed to survive both re-entry and Earth impact. The Design Iteration Test (DIT) series is part of an ongoing impact test program. The fifth test (DIT-5) was designed to compare the impact response of a GPHS fueled clad that had been welded with a four-pole arc oscillator with the impact response of a clad welded with a two-pole oscillator. In DIT-5 a partial GPHS module containing two fueled clads (one welded with a four-pole oscillator and one welded with a two-pole oscillator) was impacted at 60.5 m/s and 930/sup 0/C. The fuel capsules were severely deformed by the impact; both clads breached. The capsule welded with a four-pole oscillator failed extensively. Neither failure was related to the welding technique. Postimpact analyses of the test components are described, with emphasis on microstructure and impact response.

  12. General-purpose heat source: Research and development program. Process evaluation, fuel pellet GF-47

    SciTech Connect

    Reimus, M.A.H.; George, T.G.

    1995-12-01

    The general-purpose heat source (GPHS) provides power for space missions by transmitting the heat of {sup 238}Pu decay to an array of thermoelectric elements. Because the potential for a launch abort or return from orbit exists for any space mission, the heat source must be designed and constructed to survive credible accident environments. Previous testing conducted in support of the Galileo and Ulysses missions has documented the response of the GPHS heat source to a variety of fragment-impact, aging, atmospheric reentry, and Earth-impact conditions. Although heat sources for previous missions were fabricated by the Westinghouse Savannah River Company (WSRC), GPHS fueled-clads required for the Cassini mission to Saturn will be fabricated by Los Alamos National Laboratory (LANL). This evaluation is part of an ongoing program to determine the similarity of GPHS fueled clads and fuel pellets fabricated at LANL to those fabricated at WSRC. Pellet GF-47, which was fabricated at LANL in late 1994, was submitted for chemical and ceramographic analysis. The results indicated that the pellet had a chemical makeup and microstructure within the range of material fabricated at WSRC in the early 1980s.

  13. General-Purpose Heat Source development: Safety Verification Test Program. Bullet/fragment test series

    SciTech Connect

    George, T.G.; Tate, R.E.; Axler, K.M.

    1985-05-01

    The radioisotope thermoelectric generator (RTG) that will provide power for space missions contains 18 General-Purpose Heat Source (GPHS) modules. Each module contains four /sup 238/PuO/sub 2/-fueled clads and generates 250 W/sub (t)/. Because a launch-pad or post-launch explosion is always possible, we need to determine the ability of GPHS fueled clads within a module to survive fragment impact. The bullet/fragment test series, part of the Safety Verification Test Plan, was designed to provide information on clad response to impact by a compact, high-energy, aluminum-alloy fragment and to establish a threshold value of fragment energy required to breach the iridium cladding. Test results show that a velocity of 555 m/s (1820 ft/s) with an 18-g bullet is at or near the threshold value of fragment velocity that will cause a clad breach. Results also show that an exothermic Ir/Al reaction occurs if aluminum and hot iridium are in contact, a contact that is possible and most damaging to the clad within a narrow velocity range. The observed reactions between the iridium and the aluminum were studied in the laboratory and are reported in the Appendix.

  14. Advanced Ultrasonic Inspection Techniques for General Purpose Heat Source Fueled Clad Closure Welds

    SciTech Connect

    Moyer, M.W.

    2001-01-11

    A radioisotope thermoelectric generator is used to provide a power source for long-term deep space missions. This General Purpose Heat Source (GPHS) is fabricated using iridium clad vent sets to contain the plutonium oxide fuel pellets. Integrity of the closure weld is essential to ensure containment of the plutonium. The Oak Ridge Y-12 Plant took the lead role in developing the ultrasonic inspection for the closure weld and transferring the inspection to Los Alamos National Laboratory for use in fueled clad inspection for the Cassini mission. Initially only amplitude and time-of-flight data were recorded. However, a number of benign geometric conditions produced signals that were larger than the acceptance threshold. To identify these conditions, a B-scan inspection was developed that acquired full ultrasonic waveforms. Using a test protocol the B-scan inspection was able to identify benign conditions such as weld shield fusion and internal mismatch. Tangential radiography was used to confirm the ultrasonic results. All but two of 29 fueled clads for which ultrasonic B-scan data was evaluated appeared to have signals that could be attributed to benign geometric conditions. This report describes the ultrasonic inspection developed at Y-12 for the Cassini mission.

  15. Applications of artificial intelligence to space station: General purpose intelligent sensor interface

    NASA Technical Reports Server (NTRS)

    Mckee, James W.

    1988-01-01

    This final report describes the accomplishments of the General Purpose Intelligent Sensor Interface task of the Applications of Artificial Intelligence to Space Station grant for the period from October 1, 1987 through September 30, 1988. Portions of the First Biannual Report not revised will not be included but only referenced. The goal is to develop an intelligent sensor system that will simplify the design and development of expert systems using sensors of the physical phenomena as a source of data. This research will concentrate on the integration of image processing sensors and voice processing sensors with a computer designed for expert system development. The result of this research will be the design and documentation of a system in which the user will not need to be an expert in such areas as image processing algorithms, local area networks, image processor hardware selection or interfacing, television camera selection, voice recognition hardware selection, or analog signal processing. The user will be able to access data from video or voice sensors through standard LISP statements without any need to know about the sensor hardware or software.

  16. Production of general purpose heat source (GPHS) using advanced manufacturing methods

    NASA Astrophysics Data System (ADS)

    Miller, Roger G.

    1996-03-01

    Mankind will continue to explore the stars through the use of unmanned space craft until the technology and costs are compatible with sending travelers to the outer planets of our solar system and beyond. Unmanned probes of the present and future will be necessary to develop the necessary technologies and obtain information that will make this travel possible. Because of the significant costs incurred, the use of modern manufacturing technologies must be used to lower the investment needed even when shared by international partnerships. For over the last 30 years, radioisotopes have provided the heat from which electrical power is extracted. Electric power for future spacecraft will be provided by either Radioisotope Thermoelectric Generators (RTG), Radioisotopic Thermophotovoltaic systems (RTPV), radioisotope Stirling systems, or a combination of these. All of these systems will be thermally driven by General Purpose Heat Source (GPHS) fueled clad in some configuration. The GPHS clad contains a 238PuO2 pellet encapsulated in an iridium alloy container. Historically, the fabrication of the iridium alloy shells has been performed at EG&G Mound and Oak Ridge National Laboratory (ORNL), and girth welding at Westinghouse Savannah River Corporation (WSRC) and Los Alamos National Laboratory (LANL). This paper will describe the use of laser processing for welding, drilling, cutting, and machining with other manufacturing methods to reduce the costs of producing GPHS fueled clad components and compléted assemblies. Incorporation of new quality technologies will compliment these manufacturing methods to reduce cost.

  17. Nondestructive inspection of General Purpose Heat Source (GPHS) fueled clad girth welds

    SciTech Connect

    Reimus, M. A. H.; George, T. G.; Lynch, C.; Padilla, M.; Moniz, P.; Guerrero, A.; Moyer, M. W.; Placr, A.

    1998-01-15

    The General-Purpose Heat Source (GPHS) provides power for space missions by transmitting the heat of {sup 238}Pu decay to an array of thermoelectric elements. The GPHS is fabricated using an iridium-alloy to contain the {sup 238}PuO{sub 2} fuel pellet. GPHS capsules will be utilized in the upcoming Cassini mission to explore Saturn and its moons. The physical integrity of the girth weld is important to mission safety and performance. Because past experience had revealed a potential for initiation of small cracks in the girth weld overlap zone, a nondestructive inspection of each capsule weld is required. An ultrasonic method was used to inspect the welds of capsules fabricated for the Galileo mission. The instrument, transducer, and method used were state of the art at the time (early 1980s). The ultrasonic instrumentation and methods used to inspect the Cassini GPHSs was significantly upgraded from those used for the Galileo mission. GPHSs that had ultrasonic reflectors in excess of the reject specification level were subsequently inspected with radiography to provide additional engineering data used to accept/reject the heat source. This paper describes the Galileo-era ultrasonic instrumentation and methods and the subsequent upgrades made to support testing of Cassini GPHSs. Also discussed is the data obtained from radiographic examination and correlation to ultrasonic examination results.

  18. Nondestructive inspection of General Purpose Heat Source (GPHS) fueled clad girth welds

    SciTech Connect

    Reimus, M.A.; George, T.G.; Lynch, C.; Padilla, M.; Moniz, P.; Guerrero, A.; Moyer, M.W.; Placr, A.

    1998-01-01

    The General-Purpose Heat Source (GPHS) provides power for space missions by transmitting the heat of {sup 238}Pu decay to an array of thermoelectric elements. The GPHS is fabricated using an iridium-alloy to contain the {sup 238}PuO{sub 2} fuel pellet. GPHS capsules will be utilized in the upcoming Cassini mission to explore Saturn and its moons. The physical integrity of the girth weld is important to mission safety and performance. Because past experience had revealed a potential for initiation of small cracks in the girth weld overlap zone, a nondestructive inspection of each capsule weld is required. An ultrasonic method was used to inspect the welds of capsules fabricated for the Galileo mission. The instrument, transducer, and method used were state of the art at the time (early 1980s). The ultrasonic instrumentation and methods used to inspect the Cassini GPHSs was significantly upgraded from those used for the Galileo mission. GPHSs that had ultrasonic reflectors in excess of the reject specification level were subsequently inspected with radiography to provide additional engineering data used to accept/reject the heat source. This paper describes the Galileo-era ultrasonic instrumentation and methods and the subsequent upgrades made to support testing of Cassini GPHSs. Also discussed is the data obtained from radiographic examination and correlation to ultrasonic examination results. {copyright} {ital 1998 American Institute of Physics.}

  19. Explosion overpressure test series: General-Purpose Heat Source development: Safety Verification Test program

    SciTech Connect

    Cull, T.A.; George, T.G.; Pavone, D.

    1986-09-01

    The General-Purpose Heat Source (GPHS) is a modular, radioisotope heat source that will be used in radioisotope thermoelectric generators (RTGs) to supply electric power for space missions. The first two uses will be the NASA Galileo and the ESA Ulysses missions. The RTG for these missions will contain 18 GPHS modules, each of which contains four /sup 238/PuO/sub 2/-fueled clads and generates 250 W/sub (t)/. A series of Safety Verification Tests (SVTs) was conducted to assess the ability of the GPHS modules to contain the plutonia in accident environments. Because a launch pad or postlaunch explosion of the Space Transportation System vehicle (space shuttle) is a conceivable accident, the SVT plan included a series of tests that simulated the overpressure exposure the RTG and GPHS modules could experience in such an event. Results of these tests, in which we used depleted UO/sub 2/ as a fuel simulant, suggest that exposure to overpressures as high as 15.2 MPa (2200 psi), without subsequent impact, does not result in a release of fuel.

  20. General-purpose heat source project and space nuclear safety and fuels program. Progress report

    SciTech Connect

    Maraman, W.J.

    1980-02-01

    Studies related to the use of /sup 238/PuO/sub 2/ in radioisotopic power systems carried out for the Advanced Nuclear Systems and Projects Division of LASL are presented. The three programs involved are: general-purpose heat source development; space nuclear safety; and fuels program. Three impact tests were conducted to evaluate the effects of a high temperature reentry pulse and the use of CBCF on impact performance. Additionally, two /sup 238/PuO/sub 2/ pellets were encapsulated in Ir-0.3% W for impact testing. Results of the clad development test and vent testing are noted. Results of the environmental tests are summarized. Progress on the Stirling isotope power systems test and the status of the improved MHW tests are indicated. The examination of the impact failure of the iridium shell of MHFT-65 at a fuel pass-through continued. A test plan was written for vibration testing of the assembled light-weight radioisotopic heater unit. Progress on fuel processing is reported.

  1. deconSTRUCT: general purpose protein database search on the substructure level.

    PubMed

    Zhang, Zong Hong; Bharatham, Kavitha; Sherman, Westley A; Mihalek, Ivana

    2010-07-01

    deconSTRUCT webserver offers an interface to a protein database search engine, usable for a general purpose detection of similar protein (sub)structures. Initially, it deconstructs the query structure into its secondary structure elements (SSEs) and reassembles the match to the target by requiring a (tunable) degree of similarity in the direction and sequential order of SSEs. Hierarchical organization and judicious use of the information about protein structure enables deconSTRUCT to achieve the sensitivity and specificity of the established search engines at orders of magnitude increased speed, without tying up irretrievably the substructure information in the form of a hash. In a post-processing step, a match on the level of the backbone atoms is constructed. The results presented to the user consist of the list of the matched SSEs, the transformation matrix for rigid superposition of the structures and several ways of visualization, both downloadable and implemented as a web-browser plug-in. The server is available at http://epsf.bmad.bii.a-star.edu.sg/struct_server.html.

  2. General-Purpose Heat Source: Research and development program: Cold-Process Verification Test Series

    SciTech Connect

    Reimus, M.A.H.; George, T.G.

    1996-06-01

    The General-Purpose Heat Source (GPHS) provides power for space missions by transmitting the heat of {sup 238}Pu decay to an array of thermoelectric elements. Because any space mission could experience a launch abort or return from orbit, the heat source must be designed and constructed to survive credible accident environments. Previous testing conducted in support of the Galileo and Ulysses missions documented the response of GPHSs and individual GPHS capsules fueled with {sup 238}UO{sub 2} ({sup 235}U-depleted) to a variety of explosive overpressure and impact events. In the early 1990s, Los Alamos National Laboratory (LANL) resumed fabrication of {sup 238}UO{sub 2} GPHS pellets. The Cold-Process Verification (CPV) Test Series was designed to compare the response of GPHS heat sources loaded with recently fabricated hot- and cold-pressed {sup 238}UO{sub 2} pellets to the response of urania pellets used in the Galileo and Ulysses performance tests. This report documents eleven bare-capsule impacts and one impact of a fully loaded GPHS module. All of the failures observed in the bare-clad impact tests were similar to failures observed in previous safety tests. No failures occurred in the module impact test.

  3. Implementation and performance of a general purpose graphics processing unit in hyperspectral image analysis

    NASA Astrophysics Data System (ADS)

    van der Werff, H. M. A.; Bakker, W. H.

    2014-02-01

    A graphics processing unit (GPU) can perform massively parallel computations at relatively low cost. Software interfaces like NVIDIA CUDA allow for General Purpose computing on a GPU (GPGPU). Wrappers of the CUDA libraries for higher-level programming languages such as MATLAB and IDL allow its use in image processing. In this paper, we implement GPGPU in IDL with two distance measures frequently used in image classification, Euclidean distance and spectral angle, and apply these to hyperspectral imagery. First we vary the data volume of a synthetic dataset by changing the number of image pixels, spectral bands and classification endmembers to determine speed-up and to find the smallest data volume that would still benefit from using graphics hardware. Then we process real datasets that are too large to fit in the GPU memory, and study the effect of resulting extra data transfers on computing performance. We show that our GPU algorithms outperform the same algorithms for a central processor unit (CPU), that a significant speed-up can already be obtained on relatively small datasets, and that data transfers in large datasets do not significantly influence performance. Given that no specific knowledge on parallel computing is required for this implementation, remote sensing scientists should now be able to implement and use GPGPU for their data analysis.

  4. Environmental assessment of general-purpose heat source safety verification testing

    SciTech Connect

    1995-02-01

    This Environmental Assessment (EA) was prepared to identify and evaluate potential environmental, safety, and health impacts associated with the Proposed Action to test General-Purpose Heat Source (GPHS) Radioisotope Thermoelectric Generator (RTG) assemblies at the Sandia National Laboratories (SNL) 10,000-Foot Sled Track Facility, Albuquerque, New Mexico. RTGs are used to provide a reliable source of electrical power on board some spacecraft when solar power is inadequate during long duration space missions. These units are designed to convert heat from the natural decay of radioisotope fuel into electrical power. Impact test data are required to support DOE`s mission to provide radioisotope power systems to NASA and other user agencies. The proposed tests will expand the available safety database regarding RTG performance under postulated accident conditions. Direct observations and measurements of GPHS/RTG performance upon impact with hard, unyielding surfaces are required to verify model predictions and to ensure the continual evolution of the RTG designs that perform safely under varied accident environments. The Proposed Action is to conduct impact testing of RTG sections containing GPHS modules with simulated fuel. End-On and Side-On impact test series are planned.

  5. 17 CFR 147.1 - General policy considerations, purpose and scope of rules relating to open Commission meetings.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., purpose and scope of rules relating to open Commission meetings. 147.1 Section 147.1 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION OPEN COMMISSION MEETINGS § 147.1 General policy considerations, purpose and scope of rules relating to open Commission meetings. (a) This part contains the...

  6. Upscaling from research watersheds: an essential stage of trustworthy general-purpose hydrologic model building

    NASA Astrophysics Data System (ADS)

    McNamara, J. P.; Semenova, O.; Restrepo, P. J.

    2011-12-01

    Highly instrumented research watersheds provide excellent opportunities for investigating hydrologic processes. A danger, however, is that the processes observed at a particular research watershed are too specific to the watershed and not representative even of the larger scale watershed that contains that particular research watershed. Thus, models developed based on those partial observations may not be suitable for general hydrologic use. Therefore demonstrating the upscaling of hydrologic process from research watersheds to larger watersheds is essential to validate concepts and test model structure. The Hydrograph model has been developed as a general-purpose process-based hydrologic distributed system. In its applications and further development we evaluate the scaling of model concepts and parameters in a wide range of hydrologic landscapes. All models, either lumped or distributed, are based on a discretization concept. It is common practice that watersheds are discretized into so called hydrologic units or hydrologic landscapes possessing assumed homogeneous hydrologic functioning. If a model structure is fixed, the difference in hydrologic functioning (difference in hydrologic landscapes) should be reflected by a specific set of model parameters. Research watersheds provide the possibility for reasonable detailed combining of processes into some typical hydrologic concept such as hydrologic units, hydrologic forms, and runoff formation complexes in the Hydrograph model. And here by upscaling we imply not the upscaling of a single process but upscaling of such unified hydrologic functioning. The simulation of runoff processes for the Dry Creek research watershed, Idaho, USA (27 km2) was undertaken using the Hydrograph model. The information on the watershed was provided by Boise State University and included a GIS database of watershed characteristics and a detailed hydrometeorological observational dataset. The model provided good simulation results in

  7. Production of general purpose heat source (GPHS) using advanced manufacturing methods

    SciTech Connect

    Miller, R.G.

    1996-03-01

    Mankind will continue to explore the stars through the use of unmanned space craft until the technology and costs are compatible with sending travelers to the outer planets of our solar system and beyond. Unmanned probes of the present and future will be necessary to develop the necessary technologies and obtain information that will make this travel possible. Because of the significant costs incurred, the use of modern manufacturing technologies must be used to lower the investment needed even when shared by international partnerships. For over the last 30 years, radioisotopes have provided the heat from which electrical power is extracted. Electric power for future spacecraft will be provided by either Radioisotope Thermoelectric Generators (RTG), Radioisotopic Thermophotovoltaic systems (RTPV), radioisotope Stirling systems, or a combination of these. All of these systems will be thermally driven by General Purpose Heat Source (GPHS) fueled clad in some configuration. The GPHS clad contains a {sup 238}PuO{sub 2} pellet encapsulated in an iridium alloy container. Historically, the fabrication of the iridium alloy shells has been performed at EG&G Mound and Oak Ridge National Laboratory (ORNL), and girth welding at Westinghouse Savannah River Corporation (WSRC) and Los Alamos National Laboratory (LANL). This paper will describe the use of laser processing for welding, drilling, cutting, and machining with other manufacturing methods to reduce the costs of producing GPHS fueled clad components and compl{acute e}ted assemblies. Incorporation of new quality technologies will compliment these manufacturing methods to reduce cost. {copyright} {ital 1996 American Institute of Physics.}

  8. A General-Purpose Optimization Engine for Multi-Disciplinary Design Applications

    NASA Technical Reports Server (NTRS)

    Patnaik, Surya N.; Hopkins, Dale A.; Berke, Laszlo

    1996-01-01

    A general purpose optimization tool for multidisciplinary applications, which in the literature is known as COMETBOARDS, is being developed at NASA Lewis Research Center. The modular organization of COMETBOARDS includes several analyzers and state-of-the-art optimization algorithms along with their cascading strategy. The code structure allows quick integration of new analyzers and optimizers. The COMETBOARDS code reads input information from a number of data files, formulates a design as a set of multidisciplinary nonlinear programming problems, and then solves the resulting problems. COMETBOARDS can be used to solve a large problem which can be defined through multiple disciplines, each of which can be further broken down into several subproblems. Alternatively, a small portion of a large problem can be optimized in an effort to improve an existing system. Some of the other unique features of COMETBOARDS include design variable formulation, constraint formulation, subproblem coupling strategy, global scaling technique, analysis approximation, use of either sequential or parallel computational modes, and so forth. The special features and unique strengths of COMETBOARDS assist convergence and reduce the amount of CPU time used to solve the difficult optimization problems of aerospace industries. COMETBOARDS has been successfully used to solve a number of problems, including structural design of space station components, design of nozzle components of an air-breathing engine, configuration design of subsonic and supersonic aircraft, mixed flow turbofan engines, wave rotor topped engines, and so forth. This paper introduces the COMETBOARDS design tool and its versatility, which is illustrated by citing examples from structures, aircraft design, and air-breathing propulsion engine design.

  9. A general-purpose development environment for intelligent computer-aided training systems

    NASA Technical Reports Server (NTRS)

    Savely, Robert T.

    1990-01-01

    Space station training will be a major task, requiring the creation of large numbers of simulation-based training systems for crew, flight controllers, and ground-based support personnel. Given the long duration of space station missions and the large number of activities supported by the space station, the extension of space shuttle training methods to space station training may prove to be impractical. The application of artificial intelligence technology to simulation training can provide the ability to deliver individualized training to large numbers of personnel in a distributed workstation environment. The principal objective of this project is the creation of a software development environment which can be used to build intelligent training systems for procedural tasks associated with the operation of the space station. Current NASA Johnson Space Center projects and joint projects with other NASA operational centers will result in specific training systems for existing space shuttle crew, ground support personnel, and flight controller tasks. Concurrently with the creation of these systems, a general-purpose development environment for intelligent computer-aided training systems will be built. Such an environment would permit the rapid production, delivery, and evolution of training systems for space station crew, flight controllers, and other support personnel. The widespread use of such systems will serve to preserve task and training expertise, support the training of many personnel in a distributed manner, and ensure the uniformity and verifiability of training experiences. As a result, significant reductions in training costs can be realized while safety and the probability of mission success can be enhanced.

  10. Using general-purpose computing on graphics processing units (GPGPU) to accelerate the ordinary kriging algorithm

    NASA Astrophysics Data System (ADS)

    Gutiérrez de Ravé, E.; Jiménez-Hornero, F. J.; Ariza-Villaverde, A. B.; Gómez-López, J. M.

    2014-03-01

    Spatial interpolation methods have been applied to many disciplines, the ordinary kriging interpolation being one of the methods most frequently used. However, kriging comprises a computational cost that scales as the cube of the number of data points. Therefore, one most pressing problems in geostatistical simulations is that of developing methods that can reduce the computational time. Weights calculation and then the estimate for each unknown point is the most time-consuming step in ordinary kriging. This work investigates the potential reduction in execution time by selecting the suitable operations involved in this step to be parallelized by using general-purpose computing on graphics processing units (GPGPU) and Compute Unified Device Architecture (CUDA). This study has been performed by taking into account comparative studies between graphic and central processing units on two different machines, a personal computer (GPU, GeForce 9500, and CPU, AMD Athlon X2 4600) and a server (GPU, Tesla C1060, and CPU, Xeon 5600). In addition, two data types (float and double) have been considered in the executions. The experimental results indicate that parallel implementation of matrix inverse by using GPGPU and CUDA will be enough to reduce the execution time of weights calculation and estimation for each unknown point and, as a result, the global performance time of ordinary kriging. In addition, suitable array dimensions for using the available parallelized code have been determined for each case. Thus, it is possible to obtain relevant saved times compared to those resulting from considering wider parallelized extension. This fact demonstrates the convenience of carrying out this kind of study in other interpolation calculation methodologies using matrices.

  11. A general purpose FASTBUS master (GPM) and memory module (DSM) for online applications

    SciTech Connect

    Muller, H.

    1986-02-01

    The GPM is a high performance Fastbus master/slave, driven by 68 000 (or optionally 68 020/68 881 processors). Developed for general purpose applications it will perform control, trigger and diagnostic functions in three different experiments at CERN (DELPHI, L3, VIRTUS). Commercially available as single-board Fastbus master/slave, the GPM is a cheap processor component which can be connected to the DSM Fastbus dual-slave memory to perform as a low-level trigger processor, event formatter or data-spy. The GPM supports interprocessor interrupts via a Fastbus CSR register, interrupts on events in the Fastbus (like SR), and external interrupts. The GPM is equipped with 1/2 Mbyte of RAM, 1/4 Mbyte of ROM and a 32 Kbyte Fastbus I/O buffer. Any Fastbus operation can be generated as mixture of autonomous block transfers and assembly-language instructions which are directly executed in Fastbus. Powerful diagnostics can be performed by the possibility to address its own slave-port, via the Fastbus and the applicability of the debugging monitor commands to individual Fastbus/68 000 cycles. A terminal and host connection is available. The DMA supported parallel port can be used for interface applications. For external interrupts and coaxial pulse I/O, a NIM pulse interface is available. The 2 Mbyte Dual Slave Memory (DSM) can be used either as a stand-alone Fastbus memory, or as a memory extension module of a GPM, with independent I/O on crate and cable segments. It supports linear or circular buffer concepts and can be used as a data-spy on5cable segments.

  12. General-Purpose Heat Source development: Extended series test program large fragment tests

    SciTech Connect

    Cull, T.A.

    1989-08-01

    General-Purpose Heat Source radioisotope thermoelectric generators (GPHS-RTGs) will provide electric power for the NASA Galileo and European Space Agency Ulysses missions. Each GPHS-RTG comprises two major components: GPHS modules, which provide thermal energy, and a thermoelectric converter, which converts the thermal energy into electric power. Each of the 18 GPHS modules in a GPHS-RTG contains four /sup 238/PuO/sub 2/-fueled capsules. LANL conducted a series of safety verification tests on the GPHS-RTG before the scheduled May 1986 launch of the Galileo spacecraft to assess the ability of the GPHS modules to contain the plutonia in potential accident environments. As a result of the Challenger 51-L accident in January 1986, NASA postponed the launch of Galileo; the launch vehicle was reconfigured and the spacecraft trajectory was modified. These actions prompted NASA to reevaluate potential mission accidents, and an extended series safety test program was initiated. The program included a series of large fragment tests that simulated the collision of solid rocket booster (SRB) fragments, generated in an SRB motor case rupture or resulting from a range safety officer SRB destruct action, with the GPHS-RTG. The tests indicated that fueled clads, inside a converter, will not breach or release fuel after a square (142 cm on a side) SRB fragment impacts flat-on at velocities up to 212 m/s, and that only the leading fueled capsules breach and release fuel after the square SRB fragment impacts the modules, inside the converter, edge-on at 95 m/s. 8 refs., 32 figs., 7 tabs.

  13. 21 CFR 862.2050 - General purpose laboratory equipment labeled or promoted for a specific medical use.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY AND CLINICAL TOXICOLOGY DEVICES Clinical Laboratory Instruments § 862.2050 General purpose laboratory equipment labeled or... (general controls). The device is identified in paragraph (a) of this section and is exempt from...

  14. Coated Particles Fuel Compact-General Purpose Heat Source for Advanced Radioisotope Power Systems

    NASA Astrophysics Data System (ADS)

    El-Genk, Mohamed S.; Tournier, Jean-Michel

    2003-01-01

    Coated Particles Fuel Compacts (CPFC) have recently been shown to offer performance advantage for use in Radioisotope Heater Units (RHUs) and design flexibility for integrating at high thermal efficiency with Stirling Engine converters, currently being considered for 100 We. Advanced Radioisotope Power Systems (ARPS). The particles in the compact consist of 238PuO2 fuel kernels with 5-μm thick PyC inner coating and a strong ZrC outer coating, whose thickness depends on the maximum fuel temperature during reentry, the fuel kernel diameter, and the fraction of helium gas released from the kernels and fully contained by the ZrC coating. In addition to containing the helium generated by radioactive decay of 238Pu for up to 10 years before launch and 10-15 years mission lifetime, the kernels are intentionally sized (>= 300 μm in diameter) to prevent any adverse radiological effects on reentry. This paper investigates the advantage of replacing the four iridium-clad 238PuO2 fuel pellets, the two floating graphite membranes, and the two graphite impact shells in current State-Of-The-Art (SOA) General Purpose Heat Source (GPHS) with CPFC. The total mass, thermal power, and specific power of the CPFC-GPHS are calculated as functions of the helium release fraction from the fuel kernels and maximum fuel temperature during reentry from 1500 K to 2400 K. For the same total mass and volume as SOA GPHS, the generated thermal power by single-size particles CPFC-GPHS is 260 W at Beginning-Of-Mission (BOM), versus 231 W for the GPHS. For an additional 10% increase in total mass, the CPFC-GPHS could generate 340 W BOM; 48% higher than SOA GPHS. The corresponding specific thermal power is 214 W/kg, versus 160 W/kg for SOA GPHS; a 34% increase. Therefore, for the same thermal power, the CPFC-GPHS is lighter than SOA GPHS, while it uses the same amount of 238PuO2 fuel and same aeroshell. For the same helium release fraction and fuel temperature, binary-size particles CPFC-GPHS could

  15. Variable Conductance Heat Pipe Cooling of Stirling Convertor and General Purpose Heat Source

    NASA Technical Reports Server (NTRS)

    Tarau, Calin; Schwendeman, Carl; Anderson, William G.; Cornell, Peggy A.; Schifer, Nicholas A.

    2013-01-01

    In a Stirling Radioisotope Power System (RPS), heat must be continuously removed from the General Purpose Heat Source (GPHS) modules to maintain the modules and surrounding insulation at acceptable temperatures. The Stirling convertor normally provides this cooling. If the Stirling convertor stops in the current system, the insulation is designed to spoil, preventing damage to the GPHS at the cost of an early termination of the mission. An alkali-metal Variable Conductance Heat Pipe (VCHP) can be used to passively allow multiple stops and restarts of the Stirling convertor. In a previous NASA SBIR Program, Advanced Cooling Technologies, Inc. (ACT) developed a series of sodium VCHPs as backup cooling systems for Stirling RPS. The operation of these VCHPs was demonstrated using Stirling heater head simulators and GPHS simulators. In the most recent effort, a sodium VCHP with a stainless steel envelope was designed, fabricated and tested at NASA Glenn Research Center (GRC) with a Stirling convertor for two concepts; one for the Advanced Stirling Radioisotope Generator (ASRG) back up cooling system and one for the Long-lived Venus Lander thermal management system. The VCHP is designed to activate and remove heat from the stopped convertor at a 19 degC temperature increase from the nominal vapor temperature. The 19 degC temperature increase from nominal is low enough to avoid risking standard ASRG operation and spoiling of the Multi-Layer Insulation (MLI). In addition, the same backup cooling system can be applied to the Stirling convertor used for the refrigeration system of the Long-lived Venus Lander. The VCHP will allow the refrigeration system to: 1) rest during transit at a lower temperature than nominal; 2) pre-cool the modules to an even lower temperature before the entry in Venus atmosphere; 3) work at nominal temperature on Venus surface; 4) briefly stop multiple times on the Venus surface to allow scientific measurements. This paper presents the experimental

  16. Parallelized computation for computer simulation of electrocardiograms using personal computers with multi-core CPU and general-purpose GPU.

    PubMed

    Shen, Wenfeng; Wei, Daming; Xu, Weimin; Zhu, Xin; Yuan, Shizhong

    2010-10-01

    Biological computations like electrocardiological modelling and simulation usually require high-performance computing environments. This paper introduces an implementation of parallel computation for computer simulation of electrocardiograms (ECGs) in a personal computer environment with an Intel CPU of Core (TM) 2 Quad Q6600 and a GPU of Geforce 8800GT, with software support by OpenMP and CUDA. It was tested in three parallelization device setups: (a) a four-core CPU without a general-purpose GPU, (b) a general-purpose GPU plus 1 core of CPU, and (c) a four-core CPU plus a general-purpose GPU. To effectively take advantage of a multi-core CPU and a general-purpose GPU, an algorithm based on load-prediction dynamic scheduling was developed and applied to setting (c). In the simulation with 1600 time steps, the speedup of the parallel computation as compared to the serial computation was 3.9 in setting (a), 16.8 in setting (b), and 20.0 in setting (c). This study demonstrates that a current PC with a multi-core CPU and a general-purpose GPU provides a good environment for parallel computations in biological modelling and simulation studies.

  17. Parallelized computation for computer simulation of electrocardiograms using personal computers with multi-core CPU and general-purpose GPU.

    PubMed

    Shen, Wenfeng; Wei, Daming; Xu, Weimin; Zhu, Xin; Yuan, Shizhong

    2010-10-01

    Biological computations like electrocardiological modelling and simulation usually require high-performance computing environments. This paper introduces an implementation of parallel computation for computer simulation of electrocardiograms (ECGs) in a personal computer environment with an Intel CPU of Core (TM) 2 Quad Q6600 and a GPU of Geforce 8800GT, with software support by OpenMP and CUDA. It was tested in three parallelization device setups: (a) a four-core CPU without a general-purpose GPU, (b) a general-purpose GPU plus 1 core of CPU, and (c) a four-core CPU plus a general-purpose GPU. To effectively take advantage of a multi-core CPU and a general-purpose GPU, an algorithm based on load-prediction dynamic scheduling was developed and applied to setting (c). In the simulation with 1600 time steps, the speedup of the parallel computation as compared to the serial computation was 3.9 in setting (a), 16.8 in setting (b), and 20.0 in setting (c). This study demonstrates that a current PC with a multi-core CPU and a general-purpose GPU provides a good environment for parallel computations in biological modelling and simulation studies. PMID:20674066

  18. 21 CFR 1240.80 - General requirements for water for drinking and culinary purposes.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND... and culinary purposes by any operator of a conveyance engaged in interstate traffic, except...

  19. 21 CFR 1240.80 - General requirements for water for drinking and culinary purposes.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND... and culinary purposes by any operator of a conveyance engaged in interstate traffic, except...

  20. APL/JHU free flight tests of the General Purpose Heat Source module. Testing: 5-7 March 1984

    SciTech Connect

    Baker, W.M. II

    1984-01-01

    Purpose of the test was to obtain statistical information on the dynamics of the General Purpose Heat Source (GPHS) module at terminal speeds. Models were designed to aerodynamically and dynamically represent the GPHS module. Normal and high speed photographic coverage documented the motion of the models. This report documents test parameters and techniques for the free-spin tests. It does not include data analysis.

  1. Teacher's and Students' Beliefs on English for General Academic Purposes: The Case of Iranian University Students

    ERIC Educational Resources Information Center

    Kojour, Masoud Kermani; Heirati, Javad Kia

    2015-01-01

    This study was framed in the sociocultural theory to look into the evolution of L2 learners' beliefs about the general English course during a term. One hundred ninety-eight male and female university students and their general English course teacher were randomly selected as the participants of the study. Data were gathered through the…

  2. To Promote the General Welfare: The Purpose of Law. Law in Social Studies Series.

    ERIC Educational Resources Information Center

    Suter, Coral; Croddy, Marshall

    This student booklet is part of a curriculum designed for infusion into secondary U.S. history courses to help students explore the purposes of American law. The booklet contains student readings and discussion questions and suggests learning activities. There are five units. Unit 1, "Law in a New World," examines processes used to make legal…

  3. Beyond the "Ivory Tower": Restoring the Balance of Private and Public Purposes of General Education

    ERIC Educational Resources Information Center

    Cantor, Nancy; Englot, Peter

    2013-01-01

    We in higher education have allowed the balance of the private and public purposes of liberal education to become skewed in our angst over fully embracing a central role in restoring prosperity and preparing our increasingly diverse population for the evolving responsibility of mending our fraying democracy. As we consider how best to reshape…

  4. 15 CFR 744.17 - Restrictions on certain exports and reexports of general purpose microprocessors for “military...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... incorporation into: a military item described on the U.S. Munitions List (USML) (22 CFR part 121, International... reexports of general purpose microprocessors for âmilitary end-usesâ and to âmilitary end-users.â 744.17... microprocessors for “military end-uses” and to “military end-users.” (a) General prohibition. In addition to...

  5. Evaluating the GPSS simulation model for the Viking batch computer system. [General Purpose Simulation System

    NASA Technical Reports Server (NTRS)

    Lee, J.-J.

    1976-01-01

    In anticipation of extremely heavy loading requirements by the Viking mission during the post-landing periods, a GPSS model has been developed for the purpose of simulating these requirements on the Viking batch computer system. This paper presents the effort pursued in evaluating such a model and results thereby obtained. The evaluation effort consists of selecting the evaluation approach, collecting actual test run data, making comparisons and deriving conclusions.

  6. General purpose versus special algorithms for high-speed flows with shocks

    NASA Astrophysics Data System (ADS)

    Sai, B. V. K. Satya; Zienkiewicz, O. C.; Manzari, M. T.; Lyra, P. R. M.; Morgan, K.

    1998-01-01

    In this paper we compare the performance of a new general algorithm developed recently in application to problems of high Mach number flows with the performance of specialised algorithms applicable only to such flows. It appears that the results for most examples compare well, the biggest difference occurring in that of high Mach number compression corner.

  7. A Framework for a General Purpose Intelligent Control System for Particle Accelerators. Phase II Final Report

    SciTech Connect

    Dr. Robert Westervelt; Dr. William Klein; Dr. Michael Kroupa; Eric Olsson; Rick Rothrock

    1999-06-28

    Vista Control Systems, Inc. has developed a portable system for intelligent accelerator control. The design is general in scope and is thus configurable to a wide range of accelerator facilities and control problems. The control system employs a multi-layer organization in which knowledge-based decision making is used to dynamically configure lower level optimization and control algorithms.

  8. Matching the Purpose of the General Education Curriculum with the Reality of Its Implementation

    ERIC Educational Resources Information Center

    Cottrell, Lesley; Cottrell, Scott; Wheatly, Michele; Jungblut, Bernadette; Dooley, Elizabeth A.; DiBartolomeo, Lisa

    2015-01-01

    This essay examines the current general education curriculum (gec) structure at a large institution where the gec program has been remodeled often to meet student needs. Assessment of this structure has been limited. Faculty and adviser perceptions of the gec's role in the larger curriculum, strengths, areas for improvement, and impact on student…

  9. 24 CFR 990.310 - Purpose-General policy on financial management, monitoring and reporting.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Management Systems, Monitoring, and Reporting § 990.310 Purpose—General policy on financial management, monitoring and reporting. All PHA financial management systems, reporting, and monitoring of program performance and financial reporting shall be in compliance with the requirements of 24 CFR 85.20, 85.40,...

  10. Developing the VirtualwindoW into a General Purpose Telepresence Interface

    SciTech Connect

    McKay, M D; Anderson, M O; Kinoshita, R A; Willis, W D

    1999-04-01

    An important need while using robots or remotely operated equipment is the ability for the operator or an observer to easily and accurately perceive the operating environment. A classic problem in providing a complete representation of a work area is sensory overload or excessive complexity in the human-machine interface. In addition, remote operations often benefit from depth perception capability while viewing or manipulating objects. Thus, there is an on going effort within the robotic field to develop simplified telepresence interfaces. The Department of Energy's Idaho National Engineering and Environmental Laboratory (INEEL) has been researching methods to generalize a human-machine interface for telepresence applications. Initial telepresence research conducted at the INEEL developed and implemented a concept called the VirtualwindoW. This system minimized the complexity of remote stereo viewing controls and provided the operator the "feel" of viewing the environment, including depth perception, in a natural setting. The VirtualwindoW has shown that the human-machine interface can be simplified while increasing operator performance. This paper deals with the continuing research and development of the VirtualwindoW to provide a generalized, reconfigurable system that easily utilizes commercially available components. The original system has now been expanded to include support for zoom lenses, camera blocks, wireless links, and even vehicle control.

  11. Developing the VirtualwindoW into a General Purpose Telepresence Interface

    SciTech Connect

    Kinoshita, Robert Arthur; Anderson, Matthew Oley; Mckay, Mark D; Willis, Walter David

    1999-04-01

    An important need while using robots or remotely operated equipment is the ability for the operator or an observer to easily and accurately perceive the operating environment. A classic problem in providing a complete representation of a work area is sensory overload or excessive complexity in the human–machine interface. In addition, remote operations often benefit from depth perception capability while viewing or manipulating objects. Thus, there is an on going effort within the robotic field to develop simplified telepresence interfaces. The Department of Energy’s Idaho National Engineering and Environmental Laboratory (INEEL) has been researching methods to generalize a human-machine interface for telepresence applications. Initial telepresence research conducted at the INEEL developed and implemented a concept called the VirtualwindoW. This system minimized the complexity of remote stereo viewing controls and provided the operator the “feel” of viewing the environment, including depth perception, in a natural setting. The VirtualwindoW has shown that the human-machine interface can be simplified while increasing operator performance. This paper deals with the continuing research and development of the VirtualwindoW to provide a generalized, reconfigurable system that easily utilizes commercially available components. The original system has now been expanded to include support for zoom lenses, camera blocks, wireless links, and even vehicle control.

  12. BLASTbus electronics: general-purpose readout and control for balloon-borne experiments

    NASA Astrophysics Data System (ADS)

    Benton, S. J.; Ade, P. A.; Amiri, M.; Angilè, F. E.; Bock, J. J.; Bond, J. R.; Bryan, S. A.; Chiang, H. C.; Contaldi, C. R.; Crill, B. P.; Devlin, M. J.; Dober, B.; Doré, O. P.; Farhang, M.; Filippini, J. P.; Fissel, L. M.; Fraisse, A. A.; Fukui, Y.; Galitzki, N.; Gambrel, A. E.; Gandilo, N. N.; Golwala, S. R.; Gudmundsson, J. E.; Halpern, M.; Hasselfield, M.; Hilton, G. C.; Holmes, W. A.; Hristov, V. V.; Irwin, K. D.; Jones, W. C.; Kermish, Z. D.; Klein, J.; Korotkov, A. L.; Kuo, C. L.; MacTavish, C. J.; Mason, P. V.; Matthews, T. G.; Megerian, K. G.; Moncelsi, L.; Morford, T. A.; Mroczkowski, T. K.; Nagy, J. M.; Netterfield, C. B.; Novak, G.; Nutter, D.; O'Brient, R.; Ogburn, R. W.; Pascale, E.; Poidevin, F.; Rahlin, A. S.; Reintsema, C. D.; Ruhl, J. E.; Runyan, M. C.; Savini, G.; Scott, D.; Shariff, J. A.; Soler, J. D.; Thomas, N. E.; Trangsrud, A.; Truch, M. D.; Tucker, C. E.; Tucker, G. S.; Tucker, R. S.; Turner, A. D.; Ward-Thompson, D.; Weber, A. C.; Wiebe, D. V.; Young, E. Y.

    2014-07-01

    We present the second generation BLASTbus electronics. The primary purposes of this system are detector readout, attitude control, and cryogenic housekeeping, for balloon-borne telescopes. Readout of neutron transmutation doped germanium (NTD-Ge) bolometers requires low noise and parallel acquisition of hundreds of analog signals. Controlling a telescope's attitude requires the capability to interface to a wide variety of sensors and motors, and to use them together in a fast, closed loop. To achieve these different goals, the BLASTbus system employs a flexible motherboard-daughterboard architecture. The programmable motherboard features a digital signal processor (DSP) and field-programmable gate array (FPGA), as well as slots for three daughterboards. The daughterboards provide the interface to the outside world, with versions for analog to digital conversion, and optoisolated digital input/output. With the versatility afforded by this design, the BLASTbus also finds uses in cryogenic, thermometry, and power systems. For accurate timing control to tie everything together, the system operates in a fully synchronous manner. BLASTbus electronics have been successfully deployed to the South Pole, and own on stratospheric balloons.

  13. Developing extensible lattice-Boltzmann simulationsfor general-purpose graphics-programming units

    SciTech Connect

    Walsh, S C; Saar, M O

    2011-10-27

    Lattice-Boltzmann methods are versatile numerical modeling techniques capable of reproducing a wide variety of fluid-mechanical behavior. These methods are well suited to parallel implementation, particularly on the single-instruction multiple data (SIMD) parallel processing environments found in computer graphics processing units (GPUs). Although more recent programming tools dramatically improve the ease with which GPU programs can be written, the programming environment still lacks the flexibility available to more traditional CPU programs. In particular, it may be difficult to develop modular and extensible programs that require variable on-device functionality with current GPU architectures. This paper describes a process of automatic code generation that overcomes these difficulties for lattice-Boltzmann simulations. It details the development of GPU-based modules for an extensible lattice-Boltzmann simulation package - LBHydra. The performance of the automatically generated code is compared to equivalent purpose written codes for both single-phase, multiple-phase, and multiple-component flows. The flexibility of the new method is demonstrated by simulating a rising, dissolving droplet in a porous medium with user generated lattice-Boltzmann models and subroutines.

  14. Developing extensible lattice-Boltzmann simulators for general-purpose graphics-processing units

    SciTech Connect

    Walsh, S C; Saar, M O

    2011-12-21

    Lattice-Boltzmann methods are versatile numerical modeling techniques capable of reproducing a wide variety of fluid-mechanical behavior. These methods are well suited to parallel implementation, particularly on the single-instruction multiple data (SIMD) parallel processing environments found in computer graphics processing units (GPUs). Although more recent programming tools dramatically improve the ease with which GPU programs can be written, the programming environment still lacks the flexibility available to more traditional CPU programs. In particular, it may be difficult to develop modular and extensible programs that require variable on-device functionality with current GPU architectures. This paper describes a process of automatic code generation that overcomes these difficulties for lattice-Boltzmann simulations. It details the development of GPU-based modules for an extensible lattice-Boltzmann simulation package - LBHydra. The performance of the automatically generated code is compared to equivalent purpose written codes for both single-phase, multiple-phase, and multiple-component flows. The flexibility of the new method is demonstrated by simulating a rising, dissolving droplet in a porous medium with user generated lattice-Boltzmann models and subroutines.

  15. FLUENT/BFC - A general purpose fluid flow modeling program for all flow speeds

    NASA Astrophysics Data System (ADS)

    Dvinsky, Arkady S.

    FLUENT/BFC is a fluid flow modeling program for a variety of applications. Current capabilities of the program include laminar and turbulent flows, subsonic and supersonic viscous flows, incompressible flows, time-dependent and stationary flows, isothermal flows and flows with heat transfer, Newtonian and power-law fluids. The modeling equations in the program have been written in coordinate system invariant form to accommodate the use of boundary-conforming, generally nonorthogonal coordinate systems. The boundary-conforming coordinate system can be generated using both an internal grid generator, which is an integral part of the code, and external application-specific grid generators. The internal grid generator is based on a solution of a system of elliptic partial differential equations and can produce grids for a wide variety of two- and three-dimensional geometries.

  16. Implementation of Finite Volume based Navier Stokes Algorithm Within General Purpose Flow Network Code

    NASA Technical Reports Server (NTRS)

    Schallhorn, Paul; Majumdar, Alok

    2012-01-01

    This paper describes a finite volume based numerical algorithm that allows multi-dimensional computation of fluid flow within a system level network flow analysis. There are several thermo-fluid engineering problems where higher fidelity solutions are needed that are not within the capacity of system level codes. The proposed algorithm will allow NASA's Generalized Fluid System Simulation Program (GFSSP) to perform multi-dimensional flow calculation within the framework of GFSSP s typical system level flow network consisting of fluid nodes and branches. The paper presents several classical two-dimensional fluid dynamics problems that have been solved by GFSSP's multi-dimensional flow solver. The numerical solutions are compared with the analytical and benchmark solution of Poiseulle, Couette and flow in a driven cavity.

  17. Operation of a general purpose stepping motor-encoder positioning subsystem at the National Synchrotron Light Source

    SciTech Connect

    Stubblefield, F.W.

    1985-11-01

    Four copies of a general purpose subsystem for mechanical positioning of detectors, samples, and beam line optical elements which constitute experiments at the National Synchrotron Light Source facility of Brookhaven National Laboratory have been constructed and placed into operation. Construction of a fifth subsystem unit is nearing completion. The subsystems affect mechanical positioning by controlling a set of stepping motor-encoder pairs. The units are general purpose in the sense that they receive commands over a 9600 baud asynchronous serial line compatible with the RS-232-C electrical signal standard, generate TTL-compatible streams of stepping pulses which can be used with a wide variety of stepping motors, and read back position values from a number of different types and models of position encoder. The basic structure of the motor controller subsystem is briefly reviewed. Additions to the subsystem made in response to problems indicated by actual operation of the four installed units are described in more detail.

  18. A comprehensive workflow for general-purpose neural modeling with highly configurable neuromorphic hardware systems.

    PubMed

    Brüderle, Daniel; Petrovici, Mihai A; Vogginger, Bernhard; Ehrlich, Matthias; Pfeil, Thomas; Millner, Sebastian; Grübl, Andreas; Wendt, Karsten; Müller, Eric; Schwartz, Marc-Olivier; de Oliveira, Dan Husmann; Jeltsch, Sebastian; Fieres, Johannes; Schilling, Moritz; Müller, Paul; Breitwieser, Oliver; Petkov, Venelin; Muller, Lyle; Davison, Andrew P; Krishnamurthy, Pradeep; Kremkow, Jens; Lundqvist, Mikael; Muller, Eilif; Partzsch, Johannes; Scholze, Stefan; Zühl, Lukas; Mayr, Christian; Destexhe, Alain; Diesmann, Markus; Potjans, Tobias C; Lansner, Anders; Schüffny, René; Schemmel, Johannes; Meier, Karlheinz

    2011-05-01

    In this article, we present a methodological framework that meets novel requirements emerging from upcoming types of accelerated and highly configurable neuromorphic hardware systems. We describe in detail a device with 45 million programmable and dynamic synapses that is currently under development, and we sketch the conceptual challenges that arise from taking this platform into operation. More specifically, we aim at the establishment of this neuromorphic system as a flexible and neuroscientifically valuable modeling tool that can be used by non-hardware experts. We consider various functional aspects to be crucial for this purpose, and we introduce a consistent workflow with detailed descriptions of all involved modules that implement the suggested steps: The integration of the hardware interface into the simulator-independent model description language PyNN; a fully automated translation between the PyNN domain and appropriate hardware configurations; an executable specification of the future neuromorphic system that can be seamlessly integrated into this biology-to-hardware mapping process as a test bench for all software layers and possible hardware design modifications; an evaluation scheme that deploys models from a dedicated benchmark library, compares the results generated by virtual or prototype hardware devices with reference software simulations and analyzes the differences. The integration of these components into one hardware-software workflow provides an ecosystem for ongoing preparative studies that support the hardware design process and represents the basis for the maturity of the model-to-hardware mapping software. The functionality and flexibility of the latter is proven with a variety of experimental results. PMID:21618053

  19. An LHCb general-purpose acquisition board for beam and background monitoring at the LHC

    NASA Astrophysics Data System (ADS)

    Alessio, F.; Guzik, Z.; Jacobsson, R.

    2011-01-01

    In this paper we will present an LHCb custom-made acquisition board which was developed for a continuous beam and background monitoring during LHC operations at CERN. The paper describes both the conceptual design and its performance, and concludes with results from the first period of beam operations at the LHC. The main purpose of the acquisition board is to process signals from a pair of beam pickups to continuously monitor the intensity of each bunch, and to monitor the phase of the arrival time of each proton bunch with respect to the LHC bunch clock. The extreme versatility of the board also allowed the LHCb experiment to build a high-speed and high-sensitivity readout system for a fast background monitor based on a pair of plastic scintillators. The board has demonstrated very good performance and proved to be conceptually valid during the first months of operations at the LHC. Connected to the beam pickups, it provides the LHCb experiment with a real-time measurement of the total intensity of each beam and of the arrival time of each beam at the LHCb Interaction Point. It also monitors the LHC filling scheme and the beam current per bunch at a continuous rate of 40 MHz, and assures a proper global timing of LHCb. The continuous readout of the scintillators at bunch clock speed provides the LHCb experiment with high-resolution information about the beam halo and fast losses during both injection and circulating beam. It has also provided valuable information to the LHC during machine commissioning with beam. Recent results also shows that it could contribute as a luminosity monitor independent from the LHCb experiment readout system. Beam, background and luminosity measurements are continuously fed back to the LHC in the data exchange framework between the experiments and the LHC machine aimed at improving efficiently the experimental conditions real-time.

  20. A comprehensive workflow for general-purpose neural modeling with highly configurable neuromorphic hardware systems.

    PubMed

    Brüderle, Daniel; Petrovici, Mihai A; Vogginger, Bernhard; Ehrlich, Matthias; Pfeil, Thomas; Millner, Sebastian; Grübl, Andreas; Wendt, Karsten; Müller, Eric; Schwartz, Marc-Olivier; de Oliveira, Dan Husmann; Jeltsch, Sebastian; Fieres, Johannes; Schilling, Moritz; Müller, Paul; Breitwieser, Oliver; Petkov, Venelin; Muller, Lyle; Davison, Andrew P; Krishnamurthy, Pradeep; Kremkow, Jens; Lundqvist, Mikael; Muller, Eilif; Partzsch, Johannes; Scholze, Stefan; Zühl, Lukas; Mayr, Christian; Destexhe, Alain; Diesmann, Markus; Potjans, Tobias C; Lansner, Anders; Schüffny, René; Schemmel, Johannes; Meier, Karlheinz

    2011-05-01

    In this article, we present a methodological framework that meets novel requirements emerging from upcoming types of accelerated and highly configurable neuromorphic hardware systems. We describe in detail a device with 45 million programmable and dynamic synapses that is currently under development, and we sketch the conceptual challenges that arise from taking this platform into operation. More specifically, we aim at the establishment of this neuromorphic system as a flexible and neuroscientifically valuable modeling tool that can be used by non-hardware experts. We consider various functional aspects to be crucial for this purpose, and we introduce a consistent workflow with detailed descriptions of all involved modules that implement the suggested steps: The integration of the hardware interface into the simulator-independent model description language PyNN; a fully automated translation between the PyNN domain and appropriate hardware configurations; an executable specification of the future neuromorphic system that can be seamlessly integrated into this biology-to-hardware mapping process as a test bench for all software layers and possible hardware design modifications; an evaluation scheme that deploys models from a dedicated benchmark library, compares the results generated by virtual or prototype hardware devices with reference software simulations and analyzes the differences. The integration of these components into one hardware-software workflow provides an ecosystem for ongoing preparative studies that support the hardware design process and represents the basis for the maturity of the model-to-hardware mapping software. The functionality and flexibility of the latter is proven with a variety of experimental results.

  1. Quality of healthcare websites: A comparison of a general-purpose vs. domain-specific search engine.

    PubMed

    Abraham, Joanna; Reddy, Madhu

    2007-10-11

    In a pilot study, we had five typical Internet users evaluate the quality of health websites returned by a general-purpose search engine (Google) and a healthcare-specific search engine (Healthfinder). The evaluators used a quality criteria developed by Mitretek/Health Information Technology Institute. Although both search engines provided high quality health websites, we found some important differences between the two types of search engines.

  2. A Thematic Review of Interactive Whiteboard Use in Science Education: Rationales, Purposes, Methods and General Knowledge

    NASA Astrophysics Data System (ADS)

    Ormanci, Ummuhan; Cepni, Salih; Deveci, Isa; Aydin, Ozhan

    2015-10-01

    In Turkey and many other countries, the importance of the interactive whiteboard (IWB) is increasing, and as a result, projects and studies are being conducted regarding the use of the IWB in classrooms. Accordingly, in these countries, many issues are being researched, such as the IWB's contribution to the education process, its use in classroom settings and problems that occur when using the IWB. In this context, the research and analysis of studies regarding the use of the IWB have important implications for educators, researchers and teachers. This study aims to review and analyze studies conducted regarding the use of the IWB in the field of science. Accordingly, as a thematic review of the research was deemed appropriate, extant articles available in the literature were analyzed using a matrix that consisted of general features (type of journal, year and demographic properties) and content features (rationales, aims, research methods, samples, data collections, results and suggestions). According to the findings, it was concluded that the studies regarding the use of IWBs were conducted due to deficiencies in the current literature. However, there are rare studies in which the reasons for the research were associated with the nature of science education. There were also studies that focused on the effects of the IWB on student academic success and learning outcomes. Within this context, it is evident that there is a need for further research concerning the use of IWBs in science education and for studies regarding the effect of IWBs on students' skills.

  3. General-purpose automation programming: A case study on using a graphic language

    SciTech Connect

    Mahmood, S.M.; Olsen, D.K.

    1992-10-01

    Object-oriented programming is the future direction of computer programming and automation. It provides fast, easy and very reliable methodology for developing large complicated software programs to test prototype configurations and develop computer control of multiple operations. This report is part of technology transfer to assist the petroleum industry and other engineering, science and manufacturing areas by conveying background information and the benefits of this approach that were acquired during development of the data acquisition/control/analysis/presentation software to operate a high-temperature, high-pressure steamflood laboratory. NIPER developed the background and extensive applications using object-oriented programming software using National Instruments{trademark} LabVIEW{reg sign}2 as the programming platform. The objective of developing this software was to automate the thermal lab; however, it was designed in such a way that the program would be general and could be configured to any laboratory automation during the run time. This modular program has been constructed so that application, with minor modification, can be used in other laboratory, pilot plant or commercial operations for data acquisition/control/analysist/ presentation.

  4. General-purpose automation programming: A case study on using a graphic language

    SciTech Connect

    Mahmood, S.M.; Olsen, D.K.

    1992-10-01

    Object-oriented programming is the future direction of computer programming and automation. It provides fast, easy and very reliable methodology for developing large complicated software programs to test prototype configurations and develop computer control of multiple operations. This report is part of technology transfer to assist the petroleum industry and other engineering, science and manufacturing areas by conveying background information and the benefits of this approach that were acquired during development of the data acquisition/control/analysis/presentation software to operate a high-temperature, high-pressure steamflood laboratory. NIPER developed the background and extensive applications using object-oriented programming software using National Instruments{trademark} LabVIEW{reg_sign}2 as the programming platform. The objective of developing this software was to automate the thermal lab; however, it was designed in such a way that the program would be general and could be configured to any laboratory automation during the run time. This modular program has been constructed so that application, with minor modification, can be used in other laboratory, pilot plant or commercial operations for data acquisition/control/analysist/ presentation.

  5. TOUGH2: A general-purpose numerical simulator for multiphase nonisothermal flows

    SciTech Connect

    Pruess, K.

    1991-06-01

    Numerical simulators for multiphase fluid and heat flows in permeable media have been under development at Lawrence Berkeley Laboratory for more than 10 yr. Real geofluids contain noncondensible gases and dissolved solids in addition to water, and the desire to model such `compositional` systems led to the development of a flexible multicomponent, multiphase simulation architecture known as MULKOM. The design of MULKOM was based on the recognition that the mass-and energy-balance equations for multiphase fluid and heat flows in multicomponent systems have the same mathematical form, regardless of the number and nature of fluid components and phases present. Application of MULKOM to different fluid mixtures, such as water and air, or water, oil, and gas, is possible by means of appropriate `equation-of-state` (EOS) modules, which provide all thermophysical and transport parameters of the fluid mixture and the permeable medium as a function of a suitable set of primary thermodynamic variables. Investigations of thermal and hydrologic effects from emplacement of heat-generating nuclear wastes into partially water-saturated formations prompted the development and release of a specialized version of MULKOM for nonisothermal flow of water and air, named TOUGH. TOUGH is an acronym for `transport of unsaturated groundwater and heat` and is also an allusion to the tuff formations at Yucca Mountain, Nevada. The TOUGH2 code is intended to supersede TOUGH. It offers all the capabilities of TOUGH and includes a considerably more general subset of MULKOM modules with added capabilities. The paper briefly describes the simulation methodology and user features.

  6. Fit for purpose? A case study: validation of immunological endpoint assays for the detection of cellular and humoral responses to anti-tumour DNA fusion vaccines.

    PubMed

    Mander, Ann; Chowdhury, Ferdousi; Low, Lindsey; Ottensmeier, Christian H

    2009-05-01

    Clinical trials are governed by an increasingly stringent regulatory framework, which applies to all levels of trial conduct. Study critical immunological endpoints, which define success or failure in early phase clinical immunological trials, require formal pre-trial validation. In this case study, we describe the assay validation process, during which the sensitivity, and precision of immunological endpoint assays were defined. The purpose was the evaluation of two multicentre phase I/II clinical trials from our unit in Southampton, UK, which assess the effects of DNA fusion vaccines on immune responses in HLA-A2+ patients with carcinoembryonic antigen (CEA)-expressing malignancies and prostate cancer. Validated immunomonitoring is being performed using ELISA and IFNgamma ELISPOTs to assess humoral and cellular responses to the vaccines over time. The validated primary endpoint assay, a peptide-specific CD8+ IFNgamma ELISPOT, was tested in a pre-trial study and found to be suitable for the detection of low frequency naturally occurring CEA- and prostate-derived tumour-antigen-specific T cells in patients with CEA-expressing malignancies and prostate cancer.

  7. Recent advances toward a general purpose linear-scaling quantum force field.

    PubMed

    Giese, Timothy J; Huang, Ming; Chen, Haoyuan; York, Darrin M

    2014-09-16

    Conspectus There is need in the molecular simulation community to develop new quantum mechanical (QM) methods that can be routinely applied to the simulation of large molecular systems in complex, heterogeneous condensed phase environments. Although conventional methods, such as the hybrid quantum mechanical/molecular mechanical (QM/MM) method, are adequate for many problems, there remain other applications that demand a fully quantum mechanical approach. QM methods are generally required in applications that involve changes in electronic structure, such as when chemical bond formation or cleavage occurs, when molecules respond to one another through polarization or charge transfer, or when matter interacts with electromagnetic fields. A full QM treatment, rather than QM/MM, is necessary when these features present themselves over a wide spatial range that, in some cases, may span the entire system. Specific examples include the study of catalytic events that involve delocalized changes in chemical bonds, charge transfer, or extensive polarization of the macromolecular environment; drug discovery applications, where the wide range of nonstandard residues and protonation states are challenging to model with purely empirical MM force fields; and the interpretation of spectroscopic observables. Unfortunately, the enormous computational cost of conventional QM methods limit their practical application to small systems. Linear-scaling electronic structure methods (LSQMs) make possible the calculation of large systems but are still too computationally intensive to be applied with the degree of configurational sampling often required to make meaningful comparison with experiment. In this work, we present advances in the development of a quantum mechanical force field (QMFF) suitable for application to biological macromolecules and condensed phase simulations. QMFFs leverage the benefits provided by the LSQM and QM/MM approaches to produce a fully QM method that is able to

  8. Assessment of general public perceptions toward traditional medicines used for aphrodisiac purpose in state of Penang, Malaysia.

    PubMed

    Hassali, Mohamed Azmi; Saleem, Fahad; Shafie, Asrul Akmal; Al-Qazaz, Harith Khalid; Farooqui, Maryam; Aljadhey, Hisham; Atif, Muhammad; Masood, Imran

    2012-11-01

    The study aims to evaluate general public perceptions regarding the use of Traditional and Complementary Medicines (TCM) for aphrodisiac purposes. A questionnaire based, cross-sectional study was undertaken. Respondents were selected in the state of Penang, Malaysia. A total of 392 respondents were included in the study. Descriptive statistics were used for data analysis. Chi Square/Fischer Exact tests were used where appropriate. Out of 392 respondents, 150 (38.26%) reported using specific Traditional medicines for aphrodisiac purposes. Most respondents (46.94%) agreed that aphrodisiac medicines were easily available t. Moreover, 40.31% of the respondents reported that traditional aphrodisiac medicines were cheaper than modern (prescription) medicines. This study highlights limited public knowledge regarding the use of traditional aphrodisiac medicine. Healthcare professionals should be aware of informal TCM usage when prescribing allopathic medicines.

  9. General purpose rocket furnace

    NASA Technical Reports Server (NTRS)

    Aldrich, B. R.; Whitt, W. D. (Inventor)

    1979-01-01

    A multipurpose furnace for space vehicles used for material processing experiments in an outer space environment is described. The furnace contains three separate cavities designed to process samples of the widest possible range of materials and thermal requirements. Each cavity contains three heating elements capable of independent function under the direction of an automatic and programmable control system. A heat removable mechanism is also provided for each cavity which operates in conjunction with the control system for establishing an isothermally heated cavity or a wide range of thermal gradients and cool down rates. A monitoring system compatible with the rocket telemetry provides furnace performance and sample growth rate data throughout the processing cycle.

  10. An expert system for choosing the best combination of options in a general-purpose program for automated design synthesis

    NASA Technical Reports Server (NTRS)

    Rogers, J. L., Jr.; Barthelemy, J. F. M.

    1985-01-01

    An expert system was developed to aid a user of the Automated Design Synthesis (ADS) general-purpose optimization computer program in selecting the best combination of strategy, optimizer, and one-dimensional search options for solving a problem. There are approximately 100 such combinations available in ADS. The knowledge base contains over 200 rules, and is divided into three categories: constrained problems, unconstrained problems, and constrained problems treated as unconstrained problems. The inference engine is written in LISP and is available on DEC-VAX and IBM PC/XT computers.

  11. Preliminary reentry safety assessment of the General Purpose Heat Source module for the Cassini mission: Aerospace Nuclear Safety Program

    SciTech Connect

    Conn, D.W.; Brenza, P.T.

    1993-04-01

    As asked by the U. S. Department of Energy/Office of Special Applications, and in support of the Environmental Impact Statement for the Cassini mission, The Johns Hopkins University/Applied Physics Laboratory (JHU/APL) has conducted preliminary one-dimensional ablation and thermal analyses of the General Purpose Heat Source (GPHS). The predicted earth entry conditions provided by the Jet Propulsion Laboratory (JPL) for a Cassini Venus-Venus-Earth-Jupiter Gravity Assist (VVEJGA) trajectory were used as initial conditions. The results of this study which constitute the initial reentry analysis assessment leading to the Cassini Updated Safety, Analysis Report (USAR) are discussed in this document.

  12. Preliminary reentry safety assessment of the General Purpose Heat Source module for the Cassini mission: Aerospace Nuclear Safety Program

    NASA Astrophysics Data System (ADS)

    Conn, D. W.; Brenza, P. T.

    1993-04-01

    As asked by the U.S. Department of Energy/Office of Special Applications, and in support of the Environmental Impact Statement for the Cassini mission, The Johns Hopkins University/Applied Physics Laboratory (JHU/APL) has conducted preliminary one dimensional ablation and thermal analyses of the General Purpose Heat Source (GPHS). The predicted earth entry conditions provided by the Jet Propulsion Laboratory (JPL) for a Cassini Venus - Venus - Earth - Jupiter gravity assist (VVEJGA) trajectory were used as initial conditions. The results of this study, which constitute the initial reentry analysis assessment leading to the Cassini Updated Safety Analysis Report (USAR), are discussed in this document.

  13. General-purpose heat source project and space nuclear safety and fuels program. Progress reportt, January 1980

    SciTech Connect

    Maraman, W.J.

    1980-04-01

    This formal monthly report covers the studies related to the use of /sup 238/PuO/sub 2/ in radioisotopic power systems carried out for the Advanced Nuclear Systems and Projects Division of the Los Alamos Scientific Laboratory. The two programs involved are the general-purpose heat source development and space nuclear safety and fuels. Most of the studies discussed here are of a continuing nature. Results and conclusions described may change as the work continues. Published reference to the results cited in this report should not be made without the explicit permission of the person in charge of the work.

  14. Is What I Need What I Want? Reconceptualising College Students' Needs in English Courses for General and Specific/Academic Purposes

    ERIC Educational Resources Information Center

    Liu, Jin-Yu; Chang, Yu-Jung; Yang, Fang-Ying; Sun, Yu-Chih

    2011-01-01

    The purpose of the study is to explore English as a foreign language (EFL) college students' needs in English for General Purposes (EGP) and English for Specific/Academic Purposes (ESP/EAP) courses in terms of their perceptions of three subcategories of needs--necessities, wants, and lacks--and reasons for students' course enrollment. A…

  15. Human factors in equipment development for the Space Shuttle - A study of the general purpose work station

    NASA Technical Reports Server (NTRS)

    Junge, M. K.; Giacomi, M. J.

    1981-01-01

    The results of a human factors test to assay the suitability of a prototype general purpose work station (GPWS) for biosciences experiments on the fourth Spacelab mission are reported. The evaluation was performed to verify that users of the GPWS would optimally interact with the GPWS configuration and instrumentation. Six male subjects sat on stools positioned to allow assimilation of the zero-g body posture. Trials were run concerning the operator viewing angles facing the console, the console color, procedures for injecting rates with dye, a rat blood cell count, mouse dissection, squirrel monkey transfer, and plant fixation. The trials were run for several days in order to gage improvement or poor performance conditions. Better access to the work surface was found necessary, together with more distinct and better located LEDs, better access window latches, clearer sequences on control buttons, color-coded sequential buttons, and provisions made for an intercom system when operators of the GPWS work in tandem.

  16. Evaluation of Aqueous and Powder Processing Techniques for Production of Pu-238-Fueled General Purpose Heat Sources

    SciTech Connect

    Not Available

    2008-06-01

    This report evaluates alternative processes that could be used to produce Pu-238 fueled General Purpose Heat Sources (GPHS) for radioisotope thermoelectric generators (RTG). Fabricating GPHSs with the current process has remained essentially unchanged since its development in the 1970s. Meanwhile, 30 years of technological advancements have been made in the fields of chemistry, manufacturing, ceramics, and control systems. At the Department of Energy’s request, alternate manufacturing methods were compared to current methods to determine if alternative fabrication processes could reduce the hazards, especially the production of respirable fines, while producing an equivalent GPHS product. An expert committee performed the evaluation with input from four national laboratories experienced in Pu-238 handling.

  17. Ground and flight experience with a strapdown inertial measuring unit and a general purpose airborne digital computer

    NASA Technical Reports Server (NTRS)

    Wolf, T. D.; Mccracken, R. C.

    1973-01-01

    Ground and flight tests were conducted to investigate the problems associated with using a strapdown inertial flight data system. The objectives of this investigation were to develop a three axis inertial attitude reference system, to evaluate a self-alignment technique, and to examine the problem of time-sharing a general purpose computer for the several tasks required of it. The performance of the strapdown platform/computer system that was developed was sufficiently accurate for the tasks attempted. For flights on the order of 45 minutes duration, attitude angle errors of + or -.035 radian (+ or -2 deg) in all axes were observed. Laboratory tests of the self-alignment technique gave accuracies of + or -.00075 radian in pitch and roll axes and + or -0.0045 radian in the yaw axis. Self-alignment flight results were inconsistent, since a stable solution was not obtained on windy days because of aircraft rocking motions.

  18. An expert system for choosing the best combination of options in a general purpose program for automated design synthesis

    NASA Technical Reports Server (NTRS)

    Rogers, J. L.; Barthelemy, J.-F. M.

    1986-01-01

    An expert system called EXADS has been developed to aid users of the Automated Design Synthesis (ADS) general purpose optimization program. ADS has approximately 100 combinations of strategy, optimizer, and one-dimensional search options from which to choose. It is difficult for a nonexpert to make this choice. This expert system aids the user in choosing the best combination of options based on the users knowledge of the problem and the expert knowledge stored in the knowledge base. The knowledge base is divided into three categories; constrained problems, unconstrained problems, and constrained problems being treated as unconstrained problems. The inference engine and rules are written in LISP, contains about 200 rules, and executes on DEC-VAX (with Franz-LISP) and IBM PC (with IQ-LISP) computers.

  19. General-purpose heat source: Research and development program. Radioisotope thermoelectric generator impact tests: RTG-1 and RTG-2

    SciTech Connect

    Reimus, M.A.H.; Hinckley, J.E.; George, T.G.

    1996-07-01

    The General-Purpose Heat Source (GPHS) provides power for space missions by transmitting the heat of {sup 238}Pu decay to an array of thermoelectric elements in a radioisotope thermoelectric generator (RTG). Because the potential for a launch abort or return from orbit exists for any space mission, the heat source response to credible accident scenarios is being evaluated. The first two RTG Impact Tests were designed to provide information on the response of a fully loaded RTG to end-on impact against a concrete target. The results of these tests indicated that at impact velocities up to 57 m/s the converter shell and internal components protect the GPHS capsules from excessive deformation. At higher velocities, some of the internal components of the RTG interact with the GPHS capsules to cause excessive localized deformation and failure.

  20. General-purpose heat source: Research and development program, radioisotope thermoelectric generator/thin fragment impact test

    SciTech Connect

    Reimus, M.A.H.; Hinckley, J.E.

    1996-11-01

    The general-purpose heat source provides power for space missions by transmitting the heat of {sup 238}Pu decay to an array of thermoelectric elements in a radioisotope thermoelectric generator (RTG). Because the potential for a launch abort or return from orbit exists for any space mission, the heat source response to credible accident scenarios is being evaluated. This test was designed to provide information on the response of a loaded RTG to impact by a fragment similar to the type of fragment produced by breakup of the spacecraft propulsion module system. The results of this test indicated that impact by a thin aluminum fragment traveling at 306 m/s may result in significant damage to the converter housing, failure of one fueled clad, and release of a small quantity of fuel.

  1. SafeNet: a methodology for integrating general-purpose unsafe devices in safe-robot rehabilitation systems.

    PubMed

    Vicentini, Federico; Pedrocchi, Nicola; Malosio, Matteo; Molinari Tosatti, Lorenzo

    2014-09-01

    Robot-assisted neurorehabilitation often involves networked systems of sensors ("sensory rooms") and powerful devices in physical interaction with weak users. Safety is unquestionably a primary concern. Some lightweight robot platforms and devices designed on purpose include safety properties using redundant sensors or intrinsic safety design (e.g. compliance and backdrivability, limited exchange of energy). Nonetheless, the entire "sensory room" shall be required to be fail-safe and safely monitored as a system at large. Yet, sensor capabilities and control algorithms used in functional therapies require, in general, frequent updates or re-configurations, making a safety-grade release of such devices hardly sustainable in cost-effectiveness and development time. As such, promising integrated platforms for human-in-the-loop therapies could not find clinical application and manufacturing support because of lacking in the maintenance of global fail-safe properties. Under the general context of cross-machinery safety standards, the paper presents a methodology called SafeNet for helping in extending the safety rate of Human Robot Interaction (HRI) systems using unsafe components, including sensors and controllers. SafeNet considers, in fact, the robotic system as a device at large and applies the principles of functional safety (as in ISO 13489-1) through a set of architectural procedures and implementation rules. The enabled capability of monitoring a network of unsafe devices through redundant computational nodes, allows the usage of any custom sensors and algorithms, usually planned and assembled at therapy planning-time rather than at platform design-time. A case study is presented with an actual implementation of the proposed methodology. A specific architectural solution is applied to an example of robot-assisted upper-limb rehabilitation with online motion tracking. PMID:24750989

  2. SafeNet: a methodology for integrating general-purpose unsafe devices in safe-robot rehabilitation systems.

    PubMed

    Vicentini, Federico; Pedrocchi, Nicola; Malosio, Matteo; Molinari Tosatti, Lorenzo

    2014-09-01

    Robot-assisted neurorehabilitation often involves networked systems of sensors ("sensory rooms") and powerful devices in physical interaction with weak users. Safety is unquestionably a primary concern. Some lightweight robot platforms and devices designed on purpose include safety properties using redundant sensors or intrinsic safety design (e.g. compliance and backdrivability, limited exchange of energy). Nonetheless, the entire "sensory room" shall be required to be fail-safe and safely monitored as a system at large. Yet, sensor capabilities and control algorithms used in functional therapies require, in general, frequent updates or re-configurations, making a safety-grade release of such devices hardly sustainable in cost-effectiveness and development time. As such, promising integrated platforms for human-in-the-loop therapies could not find clinical application and manufacturing support because of lacking in the maintenance of global fail-safe properties. Under the general context of cross-machinery safety standards, the paper presents a methodology called SafeNet for helping in extending the safety rate of Human Robot Interaction (HRI) systems using unsafe components, including sensors and controllers. SafeNet considers, in fact, the robotic system as a device at large and applies the principles of functional safety (as in ISO 13489-1) through a set of architectural procedures and implementation rules. The enabled capability of monitoring a network of unsafe devices through redundant computational nodes, allows the usage of any custom sensors and algorithms, usually planned and assembled at therapy planning-time rather than at platform design-time. A case study is presented with an actual implementation of the proposed methodology. A specific architectural solution is applied to an example of robot-assisted upper-limb rehabilitation with online motion tracking.

  3. Generally detected genes in comparative transcriptomics in bivalves: toward the identification of molecular markers of cellular stress response.

    PubMed

    Miao, Jingjing; Chi, Luping; Pan, Luqing; Song, Ying

    2015-01-01

    The specificity and representativeness of protein-coding genes identified by transcriptomics as biomarkers for environmental toxicological stress is crucial. We extracted the differential gene expression profile data from 49 published comparative transcriptomic studies of bivalves from January 2004 till November 2014 performed in 15 different bivalve species. Among the studies, 77 protein-coding genes were frequently detected when we use threefold of the average detection frequency as cut-off. Cellular organization and communication, protein and energy metabolism, stress response are the main functional classes of these proteins. We consider if these protein-coding genes represent common cellular stress responses of bivalves.

  4. STICK: Spike Time Interval Computational Kernel, a Framework for General Purpose Computation Using Neurons, Precise Timing, Delays, and Synchrony.

    PubMed

    Lagorce, Xavier; Benosman, Ryad

    2015-11-01

    There has been significant research over the past two decades in developing new platforms for spiking neural computation. Current neural computers are primarily developed to mimic biology. They use neural networks, which can be trained to perform specific tasks to mainly solve pattern recognition problems. These machines can do more than simulate biology; they allow us to rethink our current paradigm of computation. The ultimate goal is to develop brain-inspired general purpose computation architectures that can breach the current bottleneck introduced by the von Neumann architecture. This work proposes a new framework for such a machine. We show that the use of neuron-like units with precise timing representation, synaptic diversity, and temporal delays allows us to set a complete, scalable compact computation framework. The framework provides both linear and nonlinear operations, allowing us to represent and solve any function. We show usability in solving real use cases from simple differential equations to sets of nonlinear differential equations leading to chaotic attractors. PMID:26378879

  5. GPHS-RTG system explosion test direct course experiment 5000. [General Purpose Heat Source-Radioisotope Thermoelectric Generator

    SciTech Connect

    Not Available

    1984-03-01

    The General Purpose Heat Source-Radioisotope Thermoelectric Generator (GPHS-RTG) has been designed and is being built to provide electrical power for spacecrafts to be launched on the Space Shuttle. The objective of the RTG System Explosion Test was to expose a mock-up of the GPHS-RTG with a simulated heat source to the overpressure and impulse representative of a potential upper magnitude explosion of the Space Shuttle. The test was designed so that the heat source module would experience an overpressure at which the survival of the fuel element cladding would be expected to be marginal. Thus, the mock-up was placed where the predicted incident overpressure would be 1300 psi. The mock-up was mounted in an orientation representative of the launch configuration on the spacecraft to be used on the NASA Galileo Mission. The incident overpressure measured was in the range of 1400 to 2100 psi. The mock-up and simulated heat source were destroyed and only very small fragments were recovered. This damage is believed to have resulted from a combination of the overpressure and impact by very high velocity fragments from the ANFO sphere. Post-test analysis indicated that extreme working of the iridium clad material occurred, indicative of intensive impulsive loading on the metal.

  6. Cafe Variome: general-purpose software for making genotype-phenotype data discoverable in restricted or open access contexts.

    PubMed

    Lancaster, Owen; Beck, Tim; Atlan, David; Swertz, Morris; Thangavelu, Dhiwagaran; Veal, Colin; Dalgleish, Raymond; Brookes, Anthony J

    2015-10-01

    Biomedical data sharing is desirable, but problematic. Data "discovery" approaches-which establish the existence rather than the substance of data-precisely connect data owners with data seekers, and thereby promote data sharing. Cafe Variome (http://www.cafevariome.org) was therefore designed to provide a general-purpose, Web-based, data discovery tool that can be quickly installed by any genotype-phenotype data owner, or network of data owners, to make safe or sensitive content appropriately discoverable. Data fields or content of any type can be accommodated, from simple ID and label fields through to extensive genotype and phenotype details based on ontologies. The system provides a "shop window" in front of data, with main interfaces being a simple search box and a powerful "query-builder" that enable very elaborate queries to be formulated. After a successful search, counts of records are reported grouped by "openAccess" (data may be directly accessed), "linkedAccess" (a source link is provided), and "restrictedAccess" (facilitated data requests and subsequent provision of approved records). An administrator interface provides a wide range of options for system configuration, enabling highly customized single-site or federated networks to be established. Current uses include rare disease data discovery, patient matchmaking, and a Beacon Web service.

  7. GPU Based General-Purpose Parallel computing to Solve Nuclear Reactor In-Core fuel Management Design and Operation Problem

    SciTech Connect

    Prayudhatama, D.; Waris, A.; Kurniasih, N.; Kurniadi, R.

    2010-06-22

    In-core fuel management study is a crucial activity in nuclear power plant design and operation. Its common problem is to find an optimum arrangement of fuel assemblies inside the reactor core. Main objective for this activity is to reduce the cost of generating electricity, which can be done by altering several physical properties of the nuclear reactor without violating any of the constraints imposed by operational and safety considerations. This research try to address the problem of nuclear fuel arrangement problem, which is, leads to the multi-objective optimization problem. However, the calculation of the reactor core physical properties itself is a heavy computation, which became obstacle in solving the optimization problem by using genetic algorithm optimization.This research tends to address that problem by using the emerging General Purpose Computation on Graphics Processing Units (GPGPU) techniques implemented by C language for CUDA (Compute Unified Device Architecture) parallel programming. By using this parallel programming technique, we develop parallelized nuclear reactor fitness calculation, which is involving numerical finite difference computation. This paper describes current prototype of the parallel algorithm code we have developed on CUDA, that performs one hundreds finite difference calculation for nuclear reactor fitness evaluation in parallel by using GPU G9 Hardware Series developed by NVIDIA.

  8. The ESPAT tool: a general-purpose DSS shell for solving stochastic optimization problems in complex river-aquifer systems

    NASA Astrophysics Data System (ADS)

    Macian-Sorribes, Hector; Pulido-Velazquez, Manuel; Tilmant, Amaury

    2015-04-01

    Stochastic programming methods are better suited to deal with the inherent uncertainty of inflow time series in water resource management. However, one of the most important hurdles in their use in practical implementations is the lack of generalized Decision Support System (DSS) shells, usually based on a deterministic approach. The purpose of this contribution is to present a general-purpose DSS shell, named Explicit Stochastic Programming Advanced Tool (ESPAT), able to build and solve stochastic programming problems for most water resource systems. It implements a hydro-economic approach, optimizing the total system benefits as the sum of the benefits obtained by each user. It has been coded using GAMS, and implements a Microsoft Excel interface with a GAMS-Excel link that allows the user to introduce the required data and recover the results. Therefore, no GAMS skills are required to run the program. The tool is divided into four modules according to its capabilities: 1) the ESPATR module, which performs stochastic optimization procedures in surface water systems using a Stochastic Dual Dynamic Programming (SDDP) approach; 2) the ESPAT_RA module, which optimizes coupled surface-groundwater systems using a modified SDDP approach; 3) the ESPAT_SDP module, capable of performing stochastic optimization procedures in small-size surface systems using a standard SDP approach; and 4) the ESPAT_DET module, which implements a deterministic programming procedure using non-linear programming, able to solve deterministic optimization problems in complex surface-groundwater river basins. The case study of the Mijares river basin (Spain) is used to illustrate the method. It consists in two reservoirs in series, one aquifer and four agricultural demand sites currently managed using historical (XIV century) rights, which give priority to the most traditional irrigation district over the XX century agricultural developments. Its size makes it possible to use either the SDP or

  9. Determination of migration monomer styrene from GPPS (general purpose polystyrene) and HIPS (high impact polystyrene) cups to hot drinks.

    PubMed

    Khaksar, Mohammad-Reza; Ghazi-Khansari, Mahmoud

    2009-03-01

    In this study, 162 samples were analysed for monomer styrene content with using high performance liquid chromatography (HPLC) method in hot tea, milk, cocoa milk. The monomer styrene content, expressed in microg/l of drink and the level of migration of styrene monomer were varied from 0.61 to 8.15 for hot tea, from 0.65 to 8.30 for hot milk, from 0.71 to 8.65 for hot cocoa milk in GPPS (general purpose polystyrene), from 0.48 to 6.85 for hot tea, from 0.61 to 7.65 for hot milk, from 0.72 to 7.78 for hot cocoa milk in HIPS (high performance polystyrene) cups in different temperatures and times. The estimated limit of detection of (HPLC) method for all samples was 0.001 mg/kg. There is linear regression for styrene monomer from 1 to 10 ng/ml. Several samples spiked with a known amount of styrene monomer. The results of the recovery in study for styrene monomer were determinate to be mean, 96.1 +/- 1.92 to 99.7 +/- 1.15%. The results of this study indicate that styrene monomer from polystyrene disposable into hot and fat drinks was migrated and this migration was highly dependent on fat content and temperature of drinks. The derived concentration of styrene monomer in this study was above the EPA (Environmental protection agency) recommended level, especially in MCLG (Maximum contaminant level goal) standard. More study is needed to further elucidate this finding.

  10. GPHS motion studies for heat pulse intervals of reentries from gravity-assist trajectories. [General Purpose Heat Source Module (GPHS)

    SciTech Connect

    Lucero, E.F.; Sharbaugh, R.C.

    1990-03-01

    Motion studies of the General Purpose Heat Source Module, GPHS, were conducted in the heat pulse interval associated with entries from earth gravity assist trajectories. The APL six-degree-of-freedom reentry program designated TMAGRA6C was used. The objectives of the studies were to (1) determine the effect of ablation on GPHS motion, and (2) determine whether the GPHS module entering the earth's atmosphere from an earth-gravity-assist trajectory has a preferred orientation during the heat pulse phase of reentry. The results are given in summary form for easy visualization of the initial conditions investigated and to provide a quick-look of the resulting motion. Detail of the motion is also given for the parameters of interest for each case studied. Selected values of initial pitch rate, roll rate, and combinations of these within the range 0[degree] to 1000[degrees]/sec were investigated for initial reentry angles of -7[degrees] (shallow) and -90[degrees] (steep) and initial angles of attack of 0[degree] (broadface to the wind) and 90[degrees]. Although the studies are not exhaustive, a sufficient number of reentry conditions (initial altitude, reentry angle, angle of attack, rotational motion) have been investigated to deduce certain trends. The results also provide information on additional reentry conditions that need to be investigated. The present results show four GPHS orientations that predominate - all with some pitch oscillations and rolling motion. These are: angles of attack, [alpha][sub R] of 0[degree], 30[degrees], 90[degrees] and tumbling. It should be assumed that all these orientations are equally probable because only combinations of two initial reentry angles, [gamma][sub 0], and two values of [alpha][sub R]. have been investigated. Further the probability for any given initial rate on orientation is not known.

  11. The EB factory project. I. A fast, neural-net-based, general purpose light curve classifier optimized for eclipsing binaries

    SciTech Connect

    Paegert, Martin; Stassun, Keivan G.; Burger, Dan M.

    2014-08-01

    We describe a new neural-net-based light curve classifier and provide it with documentation as a ready-to-use tool for the community. While optimized for identification and classification of eclipsing binary stars, the classifier is general purpose, and has been developed for speed in the context of upcoming massive surveys such as the Large Synoptic Survey Telescope. A challenge for classifiers in the context of neural-net training and massive data sets is to minimize the number of parameters required to describe each light curve. We show that a simple and fast geometric representation that encodes the overall light curve shape, together with a chi-square parameter to capture higher-order morphology information results in efficient yet robust light curve classification, especially for eclipsing binaries. Testing the classifier on the ASAS light curve database, we achieve a retrieval rate of 98% and a false-positive rate of 2% for eclipsing binaries. We achieve similarly high retrieval rates for most other periodic variable-star classes, including RR Lyrae, Mira, and delta Scuti. However, the classifier currently has difficulty discriminating between different sub-classes of eclipsing binaries, and suffers a relatively low (∼60%) retrieval rate for multi-mode delta Cepheid stars. We find that it is imperative to train the classifier's neural network with exemplars that include the full range of light curve quality to which the classifier will be expected to perform; the classifier performs well on noisy light curves only when trained with noisy exemplars. The classifier source code, ancillary programs, a trained neural net, and a guide for use, are provided.

  12. The EB Factory Project. I. A Fast, Neural-net-based, General Purpose Light Curve Classifier Optimized for Eclipsing Binaries

    NASA Astrophysics Data System (ADS)

    Paegert, Martin; Stassun, Keivan G.; Burger, Dan M.

    2014-08-01

    We describe a new neural-net-based light curve classifier and provide it with documentation as a ready-to-use tool for the community. While optimized for identification and classification of eclipsing binary stars, the classifier is general purpose, and has been developed for speed in the context of upcoming massive surveys such as the Large Synoptic Survey Telescope. A challenge for classifiers in the context of neural-net training and massive data sets is to minimize the number of parameters required to describe each light curve. We show that a simple and fast geometric representation that encodes the overall light curve shape, together with a chi-square parameter to capture higher-order morphology information results in efficient yet robust light curve classification, especially for eclipsing binaries. Testing the classifier on the ASAS light curve database, we achieve a retrieval rate of 98% and a false-positive rate of 2% for eclipsing binaries. We achieve similarly high retrieval rates for most other periodic variable-star classes, including RR Lyrae, Mira, and delta Scuti. However, the classifier currently has difficulty discriminating between different sub-classes of eclipsing binaries, and suffers a relatively low (~60%) retrieval rate for multi-mode delta Cepheid stars. We find that it is imperative to train the classifier's neural network with exemplars that include the full range of light curve quality to which the classifier will be expected to perform; the classifier performs well on noisy light curves only when trained with noisy exemplars. The classifier source code, ancillary programs, a trained neural net, and a guide for use, are provided.

  13. "Why Do I Have to Take This Course?": How Academic Advisers Can Help Students Find Personal Meaning and Purpose in General Education

    ERIC Educational Resources Information Center

    Kirk-Kuwaye, Michael; Sano-Franchini, Dominic

    2015-01-01

    For a variety of reasons, student engagement in general education continues to be a challenge. Perhaps one way to increase engagement is to connect general education with a deep student need: finding meaning and purpose in their lives or exploring what some have called "big questions." Recent scholarship has defined these clusters of…

  14. Ultra-fast digital tomosynthesis reconstruction using general-purpose GPU programming for image-guided radiation therapy.

    PubMed

    Park, Justin C; Park, Sung Ho; Kim, Jin Sung; Han, Youngyih; Cho, Min Kook; Kim, Ho Kyung; Liu, Zhaowei; Jiang, Steve B; Song, Bongyong; Song, William Y

    2011-08-01

    The purpose of this work is to demonstrate an ultra-fast reconstruction technique for digital tomosynthesis (DTS) imaging based on the algorithm proposed by Feldkamp, Davis, and Kress (FDK) using standard general-purpose graphics processing unit (GPGPU) programming interface. To this end, the FDK-based DTS algorithm was programmed "in-house" with C language with utilization of 1) GPU and 2) central processing unit (CPU) cards. The GPU card consisted of 480 processing cores (2 x 240 dual chip) with 1,242 MHz processing clock speed and 1,792 MB memory space. In terms of CPU hardware, we used 2.68 GHz clock speed, 12.0 GB DDR3 RAM, on a 64-bit OS. The performance of proposed algorithm was tested on twenty-five patient cases (5 lung, 5 liver, 10 prostate, and 5 head-and-neck) scanned either with a full-fan or half-fan mode on our cone-beam computed tomography (CBCT) system. For the full-fan scans, the projections from 157.5°-202.5° (45°-scan) were used to reconstruct coronal DTS slices, whereas for the half-fan scans, the projections from both 157.5°-202.5° and 337.5°-22.5° (2 x 45°-scan) were used to reconstruct larger FOV coronal DTS slices. For this study, we chose 45°-scan angle that contained ~80 projections for the full-fan and ~160 projections with 2 x 45°-scan angle for the half-fan mode, each with 1024 x 768 pixels with 32-bit precision. Absolute pixel value differences, profiles, and contrast-to-noise ratio (CNR) calculations were performed to compare and evaluate the images reconstructed using GPU- and CPU-based implementations. The time dependence on the reconstruction volume was also tested with (512 x 512) x 16, 32, 64, 128, and 256 slices. In the end, the GPU-based implementation achieved, at most, 1.3 and 2.5 seconds to complete full reconstruction of 512 x 512 x 256 volume, for the full-fan and half-fan modes, respectively. In turn, this meant that our implementation can process > 13 projections-per-second (pps) and > 18 pps for the full

  15. A general path for large-scale solubilization of cellular proteins: From membrane receptors to multiprotein complexes

    PubMed Central

    Pullara, Filippo; Guerrero-Santoro, Jennifer; Calero, Monica; Zhang, Qiangmin; Peng, Ye; Spåhr, Henrik; Kornberg, Guy L.; Cusimano, Antonella; Stevenson, Hilary P.; Santamaria-Suarez, Hugo; Reynolds, Shelley L.; Brown, Ian S.; Monga, Satdarshan P.S.; Van Houten, Bennett; Rapić-Otrin, Vesna; Calero, Guillermo; Levine, Arthur S.

    2014-01-01

    Expression of recombinant proteins in bacterial or eukaryotic systems often results in aggregation rendering them unavailable for biochemical or structural studies. Protein aggregation is a costly problem for biomedical research. It forces research laboratories and the biomedical industry to search for alternative, more soluble, non-human proteins and limits the number of potential “druggable” targets. In this study we present a highly reproducible protocol that introduces the systematic use of an extensive number of detergents to solubilize aggregated proteins expressed in bacterial and eukaryotic systems. We validate the usefulness of this protocol by solubilizing traditionally difficult human protein targets to milligram quantities and confirm their biological activity. We use this method to solubilize monomeric or multimeric components of multi-protein complexes and demonstrate its efficacy to reconstitute large cellular machines. This protocol works equally well on cytosolic, nuclear and membrane proteins and can be easily adapted to a high throughput format. PMID:23137940

  16. A generalized method for the minimization of cellular osmotic stresses and strains during the introduction and removal of permeable cryoprotectants.

    PubMed

    Levin, R L

    1982-05-01

    The successful freeze preservation of mammalian cells and tissues usually requires the presence of high concentrations of cryoprotective agents (CPAs) such as glycerol, ethylene glycol, or dimethylsulfoxide. Unfortunately, the addition of these permeable agents to cells and tissues prior to freezing and their removal after thawing has been documented to be as damaging as the freeze-thaw process itself. This damaging process has been hypothesized to result from the drastic alterations in cell size caused by the osmotic stresses usually imposed upon cells during the introduction and removal of the cryoprotectants. Consequently, on the basis of a nonequilibrium thermodynamic model for the transport of water and a permeable CPA across cell membranes, a method has been developed to minimize these potentially lethal transient changes in cell size. This method involves the simultaneous variation of both the extracellular CPA and electrolyte or osmotic extender osmolalities in a balance, prescribed manner so that both the cellular water content and the total intracellular ionic strength remain constant as the intracellular CPA osmolarity is either raised or lowered. The theoretical analysis indicates that many of the resulting protocols are practical from the clinical point of view.

  17. Comparison of General Purpose Heat Source testing with the ANSI N43.6-1977 (R1989) sealed source standard

    SciTech Connect

    Grigsby, C.O.

    1998-03-26

    This analysis provides a comparison of the testing of Radioisotope Thermoelectric Generators (RTGs) and RTG components with the testing requirements of ANSI N43.6-1977 (R1989) ``Sealed Radioactive Sources, Categorization``. The purpose of this comparison is to demonstrate that the RTGs meet or exceed the requirements of the ANSI standard, and thus can be excluded from the radioactive inventory of the Chemistry and Metallurgy Research (CMR) building in Los Alamos per Attachment 1 of DOE STD 1027-92. The approach used in this analysis is as follows: (1) describe the ANSI sealed source classification methodology; (2) develop sealed source performance requirements for the RTG and/or RTG components based on criteria from the accident analysis for CMR; (3) compare the existing RTG or RTG component test data to the CMR requirements; and (4) determine the appropriate ANSI classification for the RTG and/or RTG components based on CMR performance requirements. The CMR requirements for treating RTGs as sealed sources are derived from the radiotoxicity of the isotope ({sup 238}P7) and amount (13 kg) of radioactive material contained in the RTG. The accident analysis for the CMR BIO identifies the bounding accidents as wing-wide fire, explosion and earthquake. These accident scenarios set the requirements for RTGs or RTG components stored within the CMR.

  18. Order-of-magnitude faster isosurface rendering in software on a PC than using dedicated general-purpose rendering hardware

    NASA Astrophysics Data System (ADS)

    Grevera, George J.; Udupa, Jayaram K.; Odhner, Dewey

    1999-05-01

    The purpose of this work is to compare the speed of isosurface rendering in software with that using dedicated hardware. Input data consists of 10 different objects form various parts of the body and various modalities with a variety of surface sizes and shapes. The software rendering technique consists of a particular method of voxel-based surface rendering, called shell rendering. The hardware method is OpenGL-based and uses the surfaces constructed from our implementation of the 'Marching Cubes' algorithm. The hardware environment consists of a variety of platforms including a Sun Ultra I with a Creator3D graphics card and a Silicon Graphics Reality Engine II, both with polygon rendering hardware, and a 300Mhz Pentium PC. The results indicate that the software method was 18 to 31 times faster than any hardware rendering methods. This work demonstrates that a software implementation of a particular rendering algorithm can outperform dedicated hardware. We conclude that for medical surface visualization, expensive dedicated hardware engines are not required. More importantly, available software algorithms on a 300Mhz Pentium PC outperform the speed of rendering via hardware engines by a factor of 18 to 31.

  19. Working memory dysfunction associated with brain functional deficits and cellular metabolic changes in patients with generalized anxiety disorder.

    PubMed

    Moon, Chung-Man; Sundaram, Thirunavukkarasu; Choi, Nam-Gil; Jeong, Gwang-Woo

    2016-08-30

    Generalized anxiety disorder (GAD) is associated with brain functional and morphological changes in connected with emotional dysregulation and cognitive deficit. This study dealt with the neural functional deficits and metabolic abnormalities in working memory (WM) task with emotion-inducing distractors in patients with GAD. Fourteen patients with GAD and 14 healthy controls underwent functional magnetic resonance imaging (fMRI) and proton magnetic resonance spectroscopy ((1)H-MRS) at 3T. In response to the emotional distractors in WM tasks, the patients concurrently showed higher activity in the hippocampus and lower activities in the superior occipital gyrus, superior parietal gyrus, dorsolateral prefrontal cortex (DLPFC) and precentral gyrus compared to the controls. MRS revealed significantly lower choline/creatine (Cho/Cr) and choline/N-acetylaspartate (Cho/NAA) ratios in the DLPFC. In particular, the Cho ratios were positively correlated with the brain activities based on blood oxygenation level-dependent signal change in the DLPFC. This study provides the first evidence for the association between the metabolic alterations and functional deficit in WM processing with emotion-inducing distractors in GAD. These findings will be helpful to understand the neural dysfunction in connection with WM impairment in GAD. PMID:27442922

  20. Working memory dysfunction associated with brain functional deficits and cellular metabolic changes in patients with generalized anxiety disorder.

    PubMed

    Moon, Chung-Man; Sundaram, Thirunavukkarasu; Choi, Nam-Gil; Jeong, Gwang-Woo

    2016-08-30

    Generalized anxiety disorder (GAD) is associated with brain functional and morphological changes in connected with emotional dysregulation and cognitive deficit. This study dealt with the neural functional deficits and metabolic abnormalities in working memory (WM) task with emotion-inducing distractors in patients with GAD. Fourteen patients with GAD and 14 healthy controls underwent functional magnetic resonance imaging (fMRI) and proton magnetic resonance spectroscopy ((1)H-MRS) at 3T. In response to the emotional distractors in WM tasks, the patients concurrently showed higher activity in the hippocampus and lower activities in the superior occipital gyrus, superior parietal gyrus, dorsolateral prefrontal cortex (DLPFC) and precentral gyrus compared to the controls. MRS revealed significantly lower choline/creatine (Cho/Cr) and choline/N-acetylaspartate (Cho/NAA) ratios in the DLPFC. In particular, the Cho ratios were positively correlated with the brain activities based on blood oxygenation level-dependent signal change in the DLPFC. This study provides the first evidence for the association between the metabolic alterations and functional deficit in WM processing with emotion-inducing distractors in GAD. These findings will be helpful to understand the neural dysfunction in connection with WM impairment in GAD.

  1. Earth Observatory Satellite system definition study. Report 5: System design and specifications. Volume 3: General purpose spacecraft segment and module specifications

    NASA Technical Reports Server (NTRS)

    1974-01-01

    The specifications for the Earth Observatory Satellite (EOS) general purpose aircraft segment are presented. The satellite is designed to provide attitude stabilization, electrical power, and a communications data handling subsystem which can support various mission peculiar subsystems. The various specifications considered include the following: (1) structures subsystem, (2) thermal control subsystem, (3) communications and data handling subsystem module, (4) attitude control subsystem module, (5) power subsystem module, and (6) electrical integration subsystem.

  2. General Purpose Monte Carlo Codes for Neutron and Photon Transport Calculations based on Continuous Energy and Multigroup Methods.

    2008-02-29

    Version 00 (1) Problems to be solved: MVP/GMVP II can solve eigenvalue and fixed-source problems. The multigroup code GMVP can solve forward and adjoint problems for neutron, photon and neutron-photon coupled transport. The continuous-energy code MVP can solve only the forward problems. Both codes can also perform time-dependent calculations. (2) Geometry description: MVP/GMVP employs combinatorial geometry to describe the calculation geometry. It describes spatial regions by the combination of the 3-dimensional objects (BODIes). Currently, themore » following objects (BODIes) can be used. - BODIes with linear surfaces : half space, parallelepiped, right parallelepiped, wedge, right hexagonal prism - BODIes with quadratic surface and linear surfaces : cylinder, sphere, truncated right cone, truncated elliptic cone, ellipsoid by rotation, general ellipsoid - Arbitrary quadratic surface and torus The rectangular and hexagonal lattice geometry can be used to describe the repeated geometry. Furthermore, the statistical geometry model is available to treat coated fuel particles or pebbles for high temperature reactors. (3) Particle sources: The various forms of energy-, angle-, space- and time-dependent distribution functions can be specified. See Abstract for more detail.« less

  3. Overview of cellular CDMA

    NASA Astrophysics Data System (ADS)

    Lee, William C. Y.

    1991-05-01

    A general description of code division multiple access (CDMA) is presented. This overview of CDMA highlights the potential of increasing capacity in future cellular communications. The author describes the mobile radio environment and its impact on narrowband and wideband propagation. The advantage of having CDMA in cellular systems is discussed, and the concept of radio capacity in cellular is introduced. The power control schemes in CDMA are analyzed in detail.

  4. Performance of the Research Animal Holding Facility (RAHF) and General Purpose Work Station (GPWS) and other hardware in the microgravity environment

    NASA Technical Reports Server (NTRS)

    Hogan, Robert P.; Dalton, Bonnie P.

    1991-01-01

    This paper discusses the performance of the Research Animal Holding Facility (RAHF) and General Purpose Work Station (GPWS) plus other associated hardware during the recent flight of Spacelab Life Sciences 1 (SLS-1). The RAHF was developed to provide proper housing (food, water, temperature control, lighting and waste management) for up to 24 rodents during flights on the Spacelab. The GPWS was designed to contain particulates and toxic chemicals generated during plant and animal handling and dissection/fixation activities during space flights. A history of the hardware development involves as well as the redesign activities prior to the actual flight are discussed.

  5. A multifunction network of computers in a large pathology department. Integration of word processing, data base management, and general purpose computing using network principles.

    PubMed

    Cechner, R L

    1983-04-01

    We report the strategies for design and implementation of a system of compatible mini- and microcomputers intended to improve efficiency of data handling and research in several clinical and academic divisions of a large university hospital department of Pathology. A dedicated, preprogrammed, multiuser, word processing computer and small standalone word processing stations connected to a general purpose minicomputer, using standard network protocols for communication, permit virtually error-free movement of data between computers doing functionally distinct tasks of word processing, data base management, and general scientific computing. User programming is minimized and is done in a simple, well-known, high-level language. We show that cost, thruput, speed, document volume, document size, revision cycle frequency, data base size, and frequency of use are important design criteria and that existing staff can be trained easily to operate the systems.

  6. From disease ontology to disease-ontology lite: statistical methods to adapt a general-purpose ontology for the test of gene-ontology associations.

    PubMed

    Du, Pan; Feng, Gang; Flatow, Jared; Song, Jie; Holko, Michelle; Kibbe, Warren A; Lin, Simon M

    2009-06-15

    Subjective methods have been reported to adapt a general-purpose ontology for a specific application. For example, Gene Ontology (GO) Slim was created from GO to generate a highly aggregated report of the human-genome annotation. We propose statistical methods to adapt the general purpose, OBO Foundry Disease Ontology (DO) for the identification of gene-disease associations. Thus, we need a simplified definition of disease categories derived from implicated genes. On the basis of the assumption that the DO terms having similar associated genes are closely related, we group the DO terms based on the similarity of gene-to-DO mapping profiles. Two types of binary distance metrics are defined to measure the overall and subset similarity between DO terms. A compactness-scalable fuzzy clustering method is then applied to group similar DO terms. To reduce false clustering, the semantic similarities between DO terms are also used to constrain clustering results. As such, the DO terms are aggregated and the redundant DO terms are largely removed. Using these methods, we constructed a simplified vocabulary list from the DO called Disease Ontology Lite (DOLite). We demonstrated that DOLite results in more interpretable results than DO for gene-disease association tests. The resultant DOLite has been used in the Functional Disease Ontology (FunDO) Web application at http://www.projects.bioinformatics.northwestern.edu/fundo.

  7. ELAS: A general-purpose computer program for the equilibrium problems of linear structures. Volume 2: Documentation of the program. [subroutines and flow charts

    NASA Technical Reports Server (NTRS)

    Utku, S.

    1969-01-01

    A general purpose digital computer program for the in-core solution of linear equilibrium problems of structural mechanics is documented. The program requires minimum input for the description of the problem. The solution is obtained by means of the displacement method and the finite element technique. Almost any geometry and structure may be handled because of the availability of linear, triangular, quadrilateral, tetrahedral, hexahedral, conical, triangular torus, and quadrilateral torus elements. The assumption of piecewise linear deflection distribution insures monotonic convergence of the deflections from the stiffer side with decreasing mesh size. The stresses are provided by the best-fit strain tensors in the least squares at the mesh points where the deflections are given. The selection of local coordinate systems whenever necessary is automatic. The core memory is used by means of dynamic memory allocation, an optional mesh-point relabelling scheme and imposition of the boundary conditions during the assembly time.

  8. High Precision Thermal, Structural and Optical Analysis of an External Occulter Using a Common Model and the General Purpose Multi-Physics Analysis Tool Cielo

    NASA Technical Reports Server (NTRS)

    Hoff, Claus; Cady, Eric; Chainyk, Mike; Kissil, Andrew; Levine, Marie; Moore, Greg

    2011-01-01

    The efficient simulation of multidisciplinary thermo-opto-mechanical effects in precision deployable systems has for years been limited by numerical toolsets that do not necessarily share the same finite element basis, level of mesh discretization, data formats, or compute platforms. Cielo, a general purpose integrated modeling tool funded by the Jet Propulsion Laboratory and the Exoplanet Exploration Program, addresses shortcomings in the current state of the art via features that enable the use of a single, common model for thermal, structural and optical aberration analysis, producing results of greater accuracy, without the need for results interpolation or mapping. This paper will highlight some of these advances, and will demonstrate them within the context of detailed external occulter analyses, focusing on in-plane deformations of the petal edges for both steady-state and transient conditions, with subsequent optical performance metrics including intensity distributions at the pupil and image plane.

  9. Update to the safety program for the general-purpose heat source radioisotope thermoelectric generators for the Galileo and Ulysses missions

    NASA Technical Reports Server (NTRS)

    Bennett, Gary L.; Bradshaw, C. T.; Englehart, Richard W.; Bartram, Bart W.; Cull, Theresa A.; Zocher, Roy W.; Eck, Marshall B.; Mukunda, Meera; Brenza, Peter T.; Chan, Chris C.

    1992-01-01

    With the rescheduling of the Galileo and Ulysses launches and the use of new upper stages following the Challenger accident, the aerospace nuclear safety program for the general-purpose heat source radioisotope thermoelectric generators (GPHS-RTGs) was extended to accommodate the new mission scenarios. As in the original safety program, the objectives were to determine the response of the GPHS-RTG to the various postulated accident environments and to determine the risk (if any) associated with these postulated accidents. The extended GPHS-RTG safety program was successfully completed in sufficient time to prepare an updated Final Safety Analysis Report (FSAR) with revisions for the October 1989 launch of the Galileo spacecraft.

  10. NIPER Lab WARDEN -- Description and LabVIEW{reg_sign} executable code of a general-purpose laboratory-automation program. Volume 1

    SciTech Connect

    Mahmood, S.M.; Olsen, D.K.

    1994-04-01

    This report is Volume 1 (the description) of a two volume series that describes a general purpose, automation computer program developed by NIPER for data acquisition/control/analysis/presentation. This software was developed to provide interactive computer control of a variety of instruments typically found in laboratories and pilot plants in order to improve efficiency in operation and safe handling of potentially hazardous operations. For example, it is easily adaptable for operating a laboratory that conducts experiments at extreme conditions of pressure and temperature, such as those found in a steamflooding laboratory. The software was developed in an object-oriented graphical language around National Instruments` LabVIEW{reg_sign} which is the future trend in automation programming.

  11. The time-resolved and extreme conditions XAS (TEXAS) facility at the European Synchrotron Radiation Facility: the general-purpose EXAFS bending-magnet beamline BM23.

    PubMed

    Mathon, O; Beteva, A; Borrel, J; Bugnazet, D; Gatla, S; Hino, R; Kantor, I; Mairs, T; Munoz, M; Pasternak, S; Perrin, F; Pascarelli, S

    2015-11-01

    BM23 is the general-purpose EXAFS bending-magnet beamline at the ESRF, replacing the former BM29 beamline in the framework of the ESRF upgrade. Its mission is to serve the whole XAS user community by providing access to a basic service in addition to the many specialized instruments available at the ESRF. BM23 offers high signal-to-noise ratio EXAFS in a large energy range (5-75 keV), continuous energy scanning for quick-EXAFS on the second timescale and a micro-XAS station delivering a spot size of 4 µm × 4 µm FWHM. It is a user-friendly facility featuring a high degree of automation, online EXAFS data reduction and a flexible sample environment.

  12. The time-resolved and extreme conditions XAS (TEXAS) facility at the European Synchrotron Radiation Facility: the general-purpose EXAFS bending-magnet beamline BM23

    PubMed Central

    Mathon, O.; Beteva, A.; Borrel, J.; Bugnazet, D.; Gatla, S.; Hino, R.; Kantor, I.; Mairs, T.; Munoz, M.; Pasternak, S.; Perrin, F.; Pascarelli, S.

    2015-01-01

    BM23 is the general-purpose EXAFS bending-magnet beamline at the ESRF, replacing the former BM29 beamline in the framework of the ESRF upgrade. Its mission is to serve the whole XAS user community by providing access to a basic service in addition to the many specialized instruments available at the ESRF. BM23 offers high signal-to-noise ratio EXAFS in a large energy range (5–75 keV), continuous energy scanning for quick-EXAFS on the second timescale and a micro-XAS station delivering a spot size of 4 µm × 4 µm FWHM. It is a user-friendly facility featuring a high degree of automation, online EXAFS data reduction and a flexible sample environment. PMID:26524321

  13. Optimization of GATE and PHITS Monte Carlo code parameters for uniform scanning proton beam based on simulation with FLUKA general-purpose code

    NASA Astrophysics Data System (ADS)

    Kurosu, Keita; Takashina, Masaaki; Koizumi, Masahiko; Das, Indra J.; Moskvin, Vadim P.

    2014-10-01

    Although three general-purpose Monte Carlo (MC) simulation tools: Geant4, FLUKA and PHITS have been used extensively, differences in calculation results have been reported. The major causes are the implementation of the physical model, preset value of the ionization potential or definition of the maximum step size. In order to achieve artifact free MC simulation, an optimized parameters list for each simulation system is required. Several authors have already proposed the optimized lists, but those studies were performed with a simple system such as only a water phantom. Since particle beams have a transport, interaction and electromagnetic processes during beam delivery, establishment of an optimized parameters-list for whole beam delivery system is therefore of major importance. The purpose of this study was to determine the optimized parameters list for GATE and PHITS using proton treatment nozzle computational model. The simulation was performed with the broad scanning proton beam. The influences of the customizing parameters on the percentage depth dose (PDD) profile and the proton range were investigated by comparison with the result of FLUKA, and then the optimal parameters were determined. The PDD profile and the proton range obtained from our optimized parameters list showed different characteristics from the results obtained with simple system. This led to the conclusion that the physical model, particle transport mechanics and different geometry-based descriptions need accurate customization in planning computational experiments for artifact-free MC simulation.

  14. Adapting machine learning techniques to censored time-to-event health record data: A general-purpose approach using inverse probability of censoring weighting.

    PubMed

    Vock, David M; Wolfson, Julian; Bandyopadhyay, Sunayan; Adomavicius, Gediminas; Johnson, Paul E; Vazquez-Benitez, Gabriela; O'Connor, Patrick J

    2016-06-01

    Models for predicting the probability of experiencing various health outcomes or adverse events over a certain time frame (e.g., having a heart attack in the next 5years) based on individual patient characteristics are important tools for managing patient care. Electronic health data (EHD) are appealing sources of training data because they provide access to large amounts of rich individual-level data from present-day patient populations. However, because EHD are derived by extracting information from administrative and clinical databases, some fraction of subjects will not be under observation for the entire time frame over which one wants to make predictions; this loss to follow-up is often due to disenrollment from the health system. For subjects without complete follow-up, whether or not they experienced the adverse event is unknown, and in statistical terms the event time is said to be right-censored. Most machine learning approaches to the problem have been relatively ad hoc; for example, common approaches for handling observations in which the event status is unknown include (1) discarding those observations, (2) treating them as non-events, (3) splitting those observations into two observations: one where the event occurs and one where the event does not. In this paper, we present a general-purpose approach to account for right-censored outcomes using inverse probability of censoring weighting (IPCW). We illustrate how IPCW can easily be incorporated into a number of existing machine learning algorithms used to mine big health care data including Bayesian networks, k-nearest neighbors, decision trees, and generalized additive models. We then show that our approach leads to better calibrated predictions than the three ad hoc approaches when applied to predicting the 5-year risk of experiencing a cardiovascular adverse event, using EHD from a large U.S. Midwestern healthcare system.

  15. Adapting machine learning techniques to censored time-to-event health record data: A general-purpose approach using inverse probability of censoring weighting.

    PubMed

    Vock, David M; Wolfson, Julian; Bandyopadhyay, Sunayan; Adomavicius, Gediminas; Johnson, Paul E; Vazquez-Benitez, Gabriela; O'Connor, Patrick J

    2016-06-01

    Models for predicting the probability of experiencing various health outcomes or adverse events over a certain time frame (e.g., having a heart attack in the next 5years) based on individual patient characteristics are important tools for managing patient care. Electronic health data (EHD) are appealing sources of training data because they provide access to large amounts of rich individual-level data from present-day patient populations. However, because EHD are derived by extracting information from administrative and clinical databases, some fraction of subjects will not be under observation for the entire time frame over which one wants to make predictions; this loss to follow-up is often due to disenrollment from the health system. For subjects without complete follow-up, whether or not they experienced the adverse event is unknown, and in statistical terms the event time is said to be right-censored. Most machine learning approaches to the problem have been relatively ad hoc; for example, common approaches for handling observations in which the event status is unknown include (1) discarding those observations, (2) treating them as non-events, (3) splitting those observations into two observations: one where the event occurs and one where the event does not. In this paper, we present a general-purpose approach to account for right-censored outcomes using inverse probability of censoring weighting (IPCW). We illustrate how IPCW can easily be incorporated into a number of existing machine learning algorithms used to mine big health care data including Bayesian networks, k-nearest neighbors, decision trees, and generalized additive models. We then show that our approach leads to better calibrated predictions than the three ad hoc approaches when applied to predicting the 5-year risk of experiencing a cardiovascular adverse event, using EHD from a large U.S. Midwestern healthcare system. PMID:26992568

  16. Real-time simulation of a spiking neural network model of the basal ganglia circuitry using general purpose computing on graphics processing units.

    PubMed

    Igarashi, Jun; Shouno, Osamu; Fukai, Tomoki; Tsujino, Hiroshi

    2011-11-01

    Real-time simulation of a biologically realistic spiking neural network is necessary for evaluation of its capacity to interact with real environments. However, the real-time simulation of such a neural network is difficult due to its high computational costs that arise from two factors: (1) vast network size and (2) the complicated dynamics of biologically realistic neurons. In order to address these problems, mainly the latter, we chose to use general purpose computing on graphics processing units (GPGPUs) for simulation of such a neural network, taking advantage of the powerful computational capability of a graphics processing unit (GPU). As a target for real-time simulation, we used a model of the basal ganglia that has been developed according to electrophysiological and anatomical knowledge. The model consists of heterogeneous populations of 370 spiking model neurons, including computationally heavy conductance-based models, connected by 11,002 synapses. Simulation of the model has not yet been performed in real-time using a general computing server. By parallelization of the model on the NVIDIA Geforce GTX 280 GPU in data-parallel and task-parallel fashion, faster-than-real-time simulation was robustly realized with only one-third of the GPU's total computational resources. Furthermore, we used the GPU's full computational resources to perform faster-than-real-time simulation of three instances of the basal ganglia model; these instances consisted of 1100 neurons and 33,006 synapses and were synchronized at each calculation step. Finally, we developed software for simultaneous visualization of faster-than-real-time simulation output. These results suggest the potential power of GPGPU techniques in real-time simulation of realistic neural networks.

  17. General-purpose heat source: Research and development program. High-siliocon fuel characterization study: Half module impact tests 1 and 2

    SciTech Connect

    Reimus, M.A.H.; George, T.G.

    1996-03-01

    The General-Purpose Heat Source (GPHS) provides power for space missions by transmitting the heat of {sup 238}Pu decay to an array of thermoelectric elements. Because any space mission could experience a launch abort or return from orbit, the heat source must be designed and constructed to survive credible accident environments. Previous testing conducted in support of the Galileo and Ulysses missions documented the response of GPHSs to a variety of fragment-impact, aging, atmospheric reentry, and earth-impact conditions. The evaluations documented in this report are part of an ongoing program to determine the effect of fuel impurities on the response of the heat source to conditions baselined during the Galileo/Ulysses test program. In the first two tests in this series, encapsulated GPHS fuel pellets containing high levels of silicon were aged, loaded into GPHS module halves, and impacted against steel plates. The results show no significant differences between the response of these capsules and the behavior of relatively low-silicon fuel pellets tested previously.

  18. A general purpose astronomy small satellite: an approach to low-cost space telescope design using space-qualified ground telescopes

    NASA Astrophysics Data System (ADS)

    Bosanac, Natasha; Do, Sydney; Wen, Hui Ying; Wicht, Anthony

    2010-07-01

    The General Purpose Astronomy - Small Satellite (GPA-SS) project studied the feasibility of developing a useful space telescope with a cost to launch below $100 million. An optical telescope assembly (OTA) designed for ground use is proposed for use in a space mission in order to take advantage of the economies of scale in existing mirror fabrication processes. This paper details the additional design, manufacture and test tasks required to flight-qualify the ground telescope. A near-infrared imaging space telescope was costed as a potential mission. Key subsystems were designed at a conceptual level. This design was used both to estimate subsystem costs and to inform the science achievable from a given telescope design. Subsystem costs were estimated from the design through a combination of previously published cost estimating relationships and vendor quotes. This paper concludes that the space-qualification of an existing ground telescope is a potential approach for making significant cost savings when designing a low cost space telescope. Additional work on design and cost estimation around the framework presented in this paper could be undertaken to add certainty to the cost estimate.

  19. The GMT-CfA, Carnegie, Catolica, Chicago Large Earth Finder (G-CLEF): a general purpose optical echelle spectrograph for the GMT with precision radial velocity capability

    NASA Astrophysics Data System (ADS)

    Szentgyorgyi, A.; Frebel, A.; Furesz, G.; Hertz, E.; Norton, T.; Bean, J.; Bergner, H.; Crane, J.; Evans, J.; Evans, I.; Gauron, T.; Jordán, A.; Park, S.; Uomoto, A.; Barnes, S.; Davis, W.; Eisenhower, M.; Epps, H.; Guzman, D.; McCracken, K.; Ordway, M.; Plummer, D.; Podgorski, W.; Weaver, D.

    2012-09-01

    The GMT-CfA, Carnegie, Catolica, Chicago Large Earth Finder (G-CLEF) is a fiber fed, optical echelle spectrograph that has undergone conceptual design for consideration as a first light instrument at the Giant Magellan Telescope. GCLEF has been designed to be a general-purpose echelle spectrograph with precision radial velocity (PRV) capability. We have defined the performance envelope of G-CLEF to address several of the highest science priorities in the Decadal Survey1. The spectrograph optical design is an asymmetric, two-arm, white pupil design. The asymmetric white pupil design is adopted to minimize the size of the refractive camera lenses. The spectrograph beam is nominally 300 mm, reduced to 200 mm after dispersion by the R4 echelle grating. The peak efficiency of the spectrograph is >35% and the passband is 3500-9500Å. The spectrograph is primarily fed with three sets of fibers to enable three observing modes: High-Throughput, Precision-Abundance and PRV. The respective resolving powers of these modes are R~ 25,000, 40,000 and 120,000. We also anticipate having an R~40,000 Multi-object Spectroscopy mode with a multiplex of ~40 fibers. In PRV mode, each of the seven 8.4m GMT primary mirror sub-apertures feeds an individual fiber, which is scrambled after pupil-slicing. The goal radial velocity precision of G-CLEF is ∂V <10 cm/sec radial. In this paper, we provide a flowdown from fiducial science programs to design parameters. We discuss the optomechanical, electrical, structural and thermal design and present a roadmap to first light at the GMT.

  20. Renewing Our Shared Purpose: Considering Ernest L. Boyer's General Education Vision for Christian Colleges and Universities. Part II

    ERIC Educational Resources Information Center

    Wells, Cynthia A.

    2014-01-01

    This article considers the significance of Boyer's work on general education for Christian colleges and universities. After beginning with a synthesis and analysis of Boyer's vast body of work on general education, this article then identifies the challenges facing those concerned with renewing the general education program in Christian…

  1. 4DCAPTURE: a general purpose software package for capturing and analyzing two- and three-dimensional motion data acquired from video sequences

    NASA Astrophysics Data System (ADS)

    Walton, James S.; Hodgson, Peter; Hallamasek, Karen; Palmer, Jake

    2003-07-01

    4DVideo is creating a general purpose capability for capturing and analyzing kinematic data from video sequences in near real-time. The core element of this capability is a software package designed for the PC platform. The software ("4DCapture") is designed to capture and manipulate customized AVI files that can contain a variety of synchronized data streams -- including audio, video, centroid locations -- and signals acquired from more traditional sources (such as accelerometers and strain gauges.) The code includes simultaneous capture or playback of multiple video streams, and linear editing of the images (together with the ancilliary data embedded in the files). Corresponding landmarks seen from two or more views are matched automatically, and photogrammetric algorithms permit multiple landmarks to be tracked in two- and three-dimensions -- with or without lens calibrations. Trajectory data can be processed within the main application or they can be exported to a spreadsheet where they can be processed or passed along to a more sophisticated, stand-alone, data analysis application. Previous attempts to develop such applications for high-speed imaging have been limited in their scope, or by the complexity of the application itself. 4DVideo has devised a friendly ("FlowStack") user interface that assists the end-user to capture and treat image sequences in a natural progression. 4DCapture employs the AVI 2.0 standard and DirectX technology which effectively eliminates the file size limitations found in older applications. In early tests, 4DVideo has streamed three RS-170 video sources to disk for more than an hour without loss of data. At this time, the software can acquire video sequences in three ways: (1) directly, from up to three hard-wired cameras supplying RS-170 (monochrome) signals; (2) directly, from a single camera or video recorder supplying an NTSC (color) signal; and (3) by importing existing video streams in the AVI 1.0 or AVI 2.0 formats. The

  2. SU-E-T-254: Optimization of GATE and PHITS Monte Carlo Code Parameters for Uniform Scanning Proton Beam Based On Simulation with FLUKA General-Purpose Code

    SciTech Connect

    Kurosu, K; Takashina, M; Koizumi, M; Das, I; Moskvin, V

    2014-06-01

    Purpose: Monte Carlo codes are becoming important tools for proton beam dosimetry. However, the relationships between the customizing parameters and percentage depth dose (PDD) of GATE and PHITS codes have not been reported which are studied for PDD and proton range compared to the FLUKA code and the experimental data. Methods: The beam delivery system of the Indiana University Health Proton Therapy Center was modeled for the uniform scanning beam in FLUKA and transferred identically into GATE and PHITS. This computational model was built from the blue print and validated with the commissioning data. Three parameters evaluated are the maximum step size, cut off energy and physical and transport model. The dependence of the PDDs on the customizing parameters was compared with the published results of previous studies. Results: The optimal parameters for the simulation of the whole beam delivery system were defined by referring to the calculation results obtained with each parameter. Although the PDDs from FLUKA and the experimental data show a good agreement, those of GATE and PHITS obtained with our optimal parameters show a minor discrepancy. The measured proton range R90 was 269.37 mm, compared to the calculated range of 269.63 mm, 268.96 mm, and 270.85 mm with FLUKA, GATE and PHITS, respectively. Conclusion: We evaluated the dependence of the results for PDDs obtained with GATE and PHITS Monte Carlo generalpurpose codes on the customizing parameters by using the whole computational model of the treatment nozzle. The optimal parameters for the simulation were then defined by referring to the calculation results. The physical model, particle transport mechanics and the different geometrybased descriptions need accurate customization in three simulation codes to agree with experimental data for artifact-free Monte Carlo simulation. This study was supported by Grants-in Aid for Cancer Research (H22-3rd Term Cancer Control-General-043) from the Ministry of Health

  3. 78 FR 20638 - Petitions to Revise General Permit for U.S. Navy to Transport Vessels for the Purpose of Sinking...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-05

    ...-229. 42 FR 2489 (Jan. 11, 1977). At that time, EPA issued a general permit to the U.S. Navy (Navy) for... pounds or more of dielectric fluid and all capacitors containing 3 pounds or more of dielectric fluid... dielectric fluid from the vessel. Reasonable efforts include, but are not necessarily limited to, the...

  4. Bioorthogonal Catalysis: A General Method To Evaluate Metal-Catalyzed Reactions in Real Time in Living Systems Using a Cellular Luciferase Reporter System.

    PubMed

    Hsu, Hsiao-Tieh; Trantow, Brian M; Waymouth, Robert M; Wender, Paul A

    2016-02-17

    The development of abiological catalysts that can function in biological systems is an emerging subject of importance with significant ramifications in synthetic chemistry and the life sciences. Herein we report a biocompatible ruthenium complex [Cp(MQA)Ru(C3H5)](+)PF6(-) 2 (Cp = cyclopentadienyl, MQA = 4-methoxyquinoline-2-carboxylate) and a general analytical method for evaluating its performance in real time based on a luciferase reporter system amenable to high throughput screening in cells and by extension to evaluation in luciferase transgenic animals. Precatalyst 2 activates alloc-protected aminoluciferin 4b, a bioluminescence pro-probe, and releases the active luminophore, aminoluciferin (4a), in the presence of luciferase-transfected cells. The formation and enzymatic turnover of 4a, an overall process selected because it emulates pro-drug activation and drug turnover by an intracellular target, is evaluated in real time by photon counting as 4a is converted by intracellular luciferase to oxyaminoluciferin and light. Interestingly, while the catalytic conversion (activation) of 4b to 4a in water produces multiple products, the presence of biological nucleophiles such as thiols prevents byproduct formation and provides almost exclusively luminophore 4a. Our studies show that precatalyst 2 activates 4b extracellularly, exhibits low toxicity at concentrations relevant to catalysis, and is comparably effective in two different cell lines. This proof of concept study shows that precatalyst 2 is a promising lead for bioorthogonal catalytic activation of pro-probes and, by analogy, similarly activatable pro-drugs. More generally, this study provides an analytical method to measure abiological catalytic activation of pro-probes and, by analogy with our earlier studies on pro-Taxol, similarly activatable pro-drugs in real time using a coupled biological catalyst that mediates a bioluminescent readout, providing tools for the study of imaging signal amplification

  5. Bioorthogonal Catalysis: A General Method To Evaluate Metal-Catalyzed Reactions in Real Time in Living Systems Using a Cellular Luciferase Reporter System

    PubMed Central

    2015-01-01

    The development of abiological catalysts that can function in biological systems is an emerging subject of importance with significant ramifications in synthetic chemistry and the life sciences. Herein we report a biocompatible ruthenium complex [Cp(MQA)Ru(C3H5)]+PF6–2 (Cp = cyclopentadienyl, MQA = 4-methoxyquinoline-2-carboxylate) and a general analytical method for evaluating its performance in real time based on a luciferase reporter system amenable to high throughput screening in cells and by extension to evaluation in luciferase transgenic animals. Precatalyst 2 activates alloc-protected aminoluciferin 4b, a bioluminescence pro-probe, and releases the active luminophore, aminoluciferin (4a), in the presence of luciferase-transfected cells. The formation and enzymatic turnover of 4a, an overall process selected because it emulates pro-drug activation and drug turnover by an intracellular target, is evaluated in real time by photon counting as 4a is converted by intracellular luciferase to oxyaminoluciferin and light. Interestingly, while the catalytic conversion (activation) of 4b to 4a in water produces multiple products, the presence of biological nucleophiles such as thiols prevents byproduct formation and provides almost exclusively luminophore 4a. Our studies show that precatalyst 2 activates 4b extracellularly, exhibits low toxicity at concentrations relevant to catalysis, and is comparably effective in two different cell lines. This proof of concept study shows that precatalyst 2 is a promising lead for bioorthogonal catalytic activation of pro-probes and, by analogy, similarly activatable pro-drugs. More generally, this study provides an analytical method to measure abiological catalytic activation of pro-probes and, by analogy with our earlier studies on pro-Taxol, similarly activatable pro-drugs in real time using a coupled biological catalyst that mediates a bioluminescent readout, providing tools for the study of imaging signal amplification and

  6. General Purpose Monte Carlo Multigroup Neutron and Gamma-Ray Transport Code System. We recommend C00474/ALLCP/02 MORSE-CGA.

    1991-08-01

    Version: 00 The original MORSE code was a multipurpose neutron and gamma-ray transport Monte Carlo code. It was designed as a tool for solving most shielding problems. Through the use of multigroup cross sections, the solution of neutron, gamma-ray, or coupled neutron-gamma-ray problems could be obtained in either the forward or adjoint mode. Time dependence for both shielding and criticality problems is provided. General three-dimensional geometry could be used with an albedo option available atmore » any material surface. Isotropic or anisotropic scattering up to a P16 expansion of the angular distribution was allowed. MORSE-CG incorporated the Mathematical Applications, Inc. (MAGI) combinatorial geometry routines. MORSE-B modifies the Monte Carlo neutron and photon transport computer code MORSE-CG by adding routines which allow various flexible options.« less

  7. General Purpose Monte Carlo Multigroup Neutron and Gamma-Ray Transport Code System with Array Geometry Capability. We recommend C00474/ALLCP/02 MORSE-CGA.

    1991-05-01

    Version 00 MORSE-CGA was developed to add the capability of modelling rectangular lattices for nuclear reactor cores or for multipartitioned structures. It thus enhances the capability of the MORSE code system. The MORSE code is a multipurpose neutron and gamma-ray transport Monte Carlo code. It has been designed as a tool for solving most shielding problems. Through the use of multigroup cross sections, the solution of neutron, gamma-ray, or coupled neutron-gamma-ray problems may be obtainedmore » in either the forward or adjoint mode. Time dependence for both shielding and criticality problems is provided. General three-dimensional geometry may be used with an albedo option available at any material surface. Isotropic or anisotropic scattering up to a P16 expansion of the angular distribution is allowed.« less

  8. Brain morphological alterations and cellular metabolic changes in patients with generalized anxiety disorder: A combined DARTEL-based VBM and (1)H-MRS study.

    PubMed

    Moon, Chung-Man; Jeong, Gwang-Woo

    2016-05-01

    Generalized anxiety disorder (GAD) is characterized by emotional dysregulation and cognitive deficit in conjunction with brain morphometric and metabolic alterations. This study assessed the combined neural morphological deficits and metabolic abnormality in patients with GAD. Thirteen patients with GAD and 13 healthy controls matched for age, sex, and education level underwent high-resolution T1-weighted MRI and proton magnetic resonance spectroscopy ((1)H-MRS) at 3Tesla. In this study, the combination of voxel-based morphometry (VBM) and (1)H-MRS was used to assess the brain morphometric and metabolic alterations in GAD. The patients showed significantly reduced white matter (WM) volumes in the midbrain (MB), precentral gyrus (PrG), dorsolateral prefrontal cortex (DLPFC) and anterior limb of the internal capsule (ALIC) compared to the controls. In MRS study, the choline/creatine (Cho/Cr) and choline/N-acetylaspartate (Cho/NAA) ratios in the DLPFC were significantly lower in the patients. Particularly, the WM volume variation of the DLPFC was positively correlated with both of the Cho/Cr and Cho/NAA ratios in patients with GAD. This study provides an evidence for the association between the morphometric deficit and metabolic changes in GAD. This finding would be helpful to understand the neural dysfunction and pathogenesis in connection with cognitive impairments in GAD. PMID:26708039

  9. Brain morphological alterations and cellular metabolic changes in patients with generalized anxiety disorder: A combined DARTEL-based VBM and (1)H-MRS study.

    PubMed

    Moon, Chung-Man; Jeong, Gwang-Woo

    2016-05-01

    Generalized anxiety disorder (GAD) is characterized by emotional dysregulation and cognitive deficit in conjunction with brain morphometric and metabolic alterations. This study assessed the combined neural morphological deficits and metabolic abnormality in patients with GAD. Thirteen patients with GAD and 13 healthy controls matched for age, sex, and education level underwent high-resolution T1-weighted MRI and proton magnetic resonance spectroscopy ((1)H-MRS) at 3Tesla. In this study, the combination of voxel-based morphometry (VBM) and (1)H-MRS was used to assess the brain morphometric and metabolic alterations in GAD. The patients showed significantly reduced white matter (WM) volumes in the midbrain (MB), precentral gyrus (PrG), dorsolateral prefrontal cortex (DLPFC) and anterior limb of the internal capsule (ALIC) compared to the controls. In MRS study, the choline/creatine (Cho/Cr) and choline/N-acetylaspartate (Cho/NAA) ratios in the DLPFC were significantly lower in the patients. Particularly, the WM volume variation of the DLPFC was positively correlated with both of the Cho/Cr and Cho/NAA ratios in patients with GAD. This study provides an evidence for the association between the morphometric deficit and metabolic changes in GAD. This finding would be helpful to understand the neural dysfunction and pathogenesis in connection with cognitive impairments in GAD.

  10. Real-Time Bioluminescent Tracking of Cellular Population Dynamics

    SciTech Connect

    Close, Dan; Sayler, Gary Steven; Xu, Tingting; Ripp, Steven Anthony

    2014-01-01

    Cellular population dynamics are routinely monitored across many diverse fields for a variety of purposes. In general, these dynamics are assayed either through the direct counting of cellular aliquots followed by extrapolation to the total population size, or through the monitoring of signal intensity from any number of externally stimulated reporter proteins. While both viable methods, here we describe a novel technique that allows for the automated, non-destructive tracking of cellular population dynamics in real-time. This method, which relies on the detection of a continuous bioluminescent signal produced through expression of the bacterial luciferase gene cassette, provides a low cost, low time-intensive means for generating additional data compared to alternative methods.

  11. General Purpose Fortran Program for Discrete-Ordinate-Method Radiative Transfer in Scattering and Emitting Layered Media: An Update of DISORT

    NASA Technical Reports Server (NTRS)

    Tsay, Si-Chee; Stamnes, Knut; Wiscombe, Warren; Laszlo, Istvan; Einaudi, Franco (Technical Monitor)

    2000-01-01

    This update reports a state-of-the-art discrete ordinate algorithm for monochromatic unpolarized radiative transfer in non-isothermal, vertically inhomogeneous, but horizontally homogeneous media. The physical processes included are Planckian thermal emission, scattering with arbitrary phase function, absorption, and surface bidirectional reflection. The system may be driven by parallel or isotropic diffuse radiation incident at the top boundary, as well as by internal thermal sources and thermal emission from the boundaries. Radiances, fluxes, and mean intensities are returned at user-specified angles and levels. DISORT has enjoyed considerable popularity in the atmospheric science and other communities since its introduction in 1988. Several new DISORT features are described in this update: intensity correction algorithms designed to compensate for the 8-M forward-peak scaling and obtain accurate intensities even in low orders of approximation; a more general surface bidirectional reflection option; and an exponential-linear approximation of the Planck function allowing more accurate solutions in the presence of large temperature gradients. DISORT has been designed to be an exemplar of good scientific software as well as a program of intrinsic utility. An extraordinary effort has been made to make it numerically well-conditioned, error-resistant, and user-friendly, and to take advantage of robust existing software tools. A thorough test suite is provided to verify the program both against published results, and for consistency where there are no published results. This careful attention to software design has been just as important in DISORT's popularity as its powerful algorithmic content.

  12. 10 CFR 205.350 - General purpose.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... OF ENERGY OIL ADMINISTRATIVE PROCEDURES AND SANCTIONS Electric Power System Permits and Reports; Applications; Administrative Procedures and Sanctions Report of Major Electric Utility System Emergencies § 205... on the electric energy supply systems in the United States so that appropriate Federal...

  13. 10 CFR 205.350 - General purpose.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... OF ENERGY OIL ADMINISTRATIVE PROCEDURES AND SANCTIONS Electric Power System Permits and Reports; Applications; Administrative Procedures and Sanctions Report of Major Electric Utility System Emergencies § 205... on the electric energy supply systems in the United States so that appropriate Federal...

  14. 10 CFR 205.350 - General purpose.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... OF ENERGY OIL ADMINISTRATIVE PROCEDURES AND SANCTIONS Electric Power System Permits and Reports; Applications; Administrative Procedures and Sanctions Report of Major Electric Utility System Emergencies § 205... on the electric energy supply systems in the United States so that appropriate Federal...

  15. A General-Purpose Graphic Plotting Package.

    ERIC Educational Resources Information Center

    Freese, David H., Jr.

    1983-01-01

    Describes subroutines in a group of assembly-level programs (program listings included) which provide the interface between a Basic, Pascal/Z, or JRT Pascal program and the BASE2/IDS-560 graphics printer. The interface can be easily modified for other printers and other languages. (JN)

  16. Photovoltaics module interface: General purpose primers

    NASA Technical Reports Server (NTRS)

    Boerio, J.

    1985-01-01

    The interfacial chemistry established between ethylene vinyl acetate (EVA) and the aluminized back surface of commercial solar cells was observed experimentally. The technique employed is called Fourier Transform Infrared (FTIR) spectroscopy, with the infrared signal being reflected back from the aluminum surface through the EVA film. Reflection infrared (IR) spectra are given and attention is drawn to the specific IR peak at 1080/cm which forms on hydrolytic aging of the EVA/aluminum system. With this fundamental finding, and the workable experimental techniques, candidate silane coupling agents are employed at the interface, and their effects on eliminating or slowing hydrolytic aging of the EVA/aluminum interface are monitored.

  17. General-Purpose Monitoring during Speech Production

    ERIC Educational Resources Information Center

    Ries, Stephanie; Janssen, Niels; Dufau, Stephane; Alario, F.-Xavier; Burle, Boris

    2011-01-01

    The concept of "monitoring" refers to our ability to control our actions on-line. Monitoring involved in speech production is often described in psycholinguistic models as an inherent part of the language system. We probed the specificity of speech monitoring in two psycholinguistic experiments where electroencephalographic activities were…

  18. Cellular mechanics and motility

    NASA Astrophysics Data System (ADS)

    Hénon, Sylvie; Sykes, Cécile

    2015-10-01

    The term motility defines the movement of a living organism. One widely known example is the motility of sperm cells, or the one of flagellar bacteria. The propulsive element of such organisms is a cilium(or flagellum) that beats. Although cells in our tissues do not have a flagellum in general, they are still able to move, as we will discover in this chapter. In fact, in both cases of movement, with or without a flagellum, cell motility is due to a dynamic re-arrangement of polymers inside the cell. Let us first have a closer look at the propulsion mechanism in the case of a flagellum or a cilium, which is the best known, but also the simplest, and which will help us to define the hydrodynamic general conditions of cell movement. A flagellum is sustained by cellular polymers arranged in semi-flexible bundles and flagellar beating generates cell displacement. These polymers or filaments are part of the cellular skeleton, or "cytoskeleton", which is, in this case, external to the cellular main body of the organism. In fact, bacteria move in a hydrodynamic regime in which viscosity dominates over inertia. The system is thus in a hydrodynamic regime of low Reynolds number (Box 5.1), which is nearly exclusively the case in all cell movements. Bacteria and their propulsion mode by flagella beating are our unicellular ancestors 3.5 billion years ago. Since then, we have evolved to form pluricellular organisms. However, to keep the ability of displacement, to heal our wounds for example, our cells lost their flagellum, since it was not optimal in a dense cell environment: cells are too close to each other to leave enough space for the flagella to accomplish propulsion. The cytoskeleton thus developed inside the cell body to ensure cell shape changes and movement, and also mechanical strength within a tissue. The cytoskeleton of our cells, like the polymers or filaments that sustain the flagellum, is also composed of semi-flexible filaments arranged in bundles, and also in

  19. Cellular: Toward personal communications

    NASA Astrophysics Data System (ADS)

    Heffernan, Stuart

    1991-09-01

    The cellular industry is one of the fastest growing segment of the telecommunications industry. With an estimated penetration rate of 20 percent in the near future, cellular is becoming an ubiquitous telecommunications service in the U.S. In this paper we will examine the major advancements in the cellular industry: customer equipment, cellular networks, engineering tools, customer support, and nationwide seamless service.

  20. Microfluidic Electroporation for Cellular Analysis and Delivery

    PubMed Central

    Geng, Tao

    2013-01-01

    Electroporation is a simple yet powerful technique for breaching cell membrane barrier. The applications of electroporation can be generally divided into two categories: the release of intracellular proteins, nucleic acids and other metabolites for analysis and the delivery of exogenous reagents such as genes, drugs and nanoparticles with therapeutic purposes or for cellular manipulation. In this review, we go over the basic physics associated with cell electroporation and highlight recent technological advances on microfluidic platforms for conducting electroporation. Within the context of its working mechanism, we summarize the accumulated knowledge on how the parameters of electroporation affect its performance for various tasks. We discuss various strategies and designs for conducting electroporation at microscale and then focus on analysis of intracellular contents and delivery of exogenous agents as two major applications of the technique. Finally, an outlook for future applications of microfluidic electroporation in increasingly diverse utilities is presented. PMID:23917998

  1. Microfluidic electroporation for cellular analysis and delivery.

    PubMed

    Geng, Tao; Lu, Chang

    2013-10-01

    Electroporation is a simple yet powerful technique for breaching the cell membrane barrier. The applications of electroporation can be generally divided into two categories: the release of intracellular proteins, nucleic acids and other metabolites for analysis and the delivery of exogenous reagents such as genes, drugs and nanoparticles with therapeutic purposes or for cellular manipulation. In this review, we go over the basic physics associated with cell electroporation and highlight recent technological advances on microfluidic platforms for conducting electroporation. Within the context of its working mechanism, we summarize the accumulated knowledge on how the parameters of electroporation affect its performance for various tasks. We discuss various strategies and designs for conducting electroporation at the microscale and then focus on analysis of intracellular contents and delivery of exogenous agents as two major applications of the technique. Finally, an outlook for future applications of microfluidic electroporation in increasingly diverse utilities is presented.

  2. 15 CFR 971.100 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS General § 971.100 Purpose....

  3. 15 CFR 971.100 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS General § 971.100 Purpose....

  4. 15 CFR 971.100 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS General § 971.100 Purpose....

  5. 15 CFR 971.100 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS General § 971.100 Purpose....

  6. 15 CFR 971.100 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS General § 971.100 Purpose....

  7. Optical cellular processor architecture. 1: Principles.

    PubMed

    Taboury, J; Wang, J M; Chavel, P; Devos, F; Garda, P

    1988-05-01

    General characteristics and advantages of 2-D optical cellular processors are listed and discussed, with reference to the concepts of cellular automata, symbolic substitution, and neural nets. The role of optical interconnections and of quasilinear processing combining linear array operations and pointwise nonlinearities is highlighted. An architecture for optical implementation of cellular automata is introduced; it features high density 3-D optical shift-invariant interconnections and programmability of the interconnection pattern through adequate use of holographic connectors.

  8. Cellular Phone Towers

    MedlinePlus

    ... the call. How are people exposed to the energy from cellular phone towers? As people use cell ... where people can be exposed to them. The energy from a cellular phone tower antenna, like that ...

  9. A Passive EMI Filter with Access to the Ungrounded Motor Neutral Line-The Case that a General-Purpose Inverter is Directly Connected to a Three-Phase Grounded Voltage Source-

    NASA Astrophysics Data System (ADS)

    Doumoto, Takafumi; Akagi, Hirofumi

    This paper proposes a small-sized passive EMI filter for the purpose of eliminating high-frequency shaft voltage and ground leakage current from an ac motor. The motor is driven by a general-purpose PWM inverter connected to a three-phase grounded voltage source. The passive EMI filter requires access to the ungrounded neutral point of the motor. This unique circuit configuration makes the common-mode inductor effective in reducing the high-frequency common-mode voltage generated by the PWM inverter with a carrier frequency of 15kHz. As a result, both high-frequency shaft voltage and ground leakage current can be eliminated very efficiently. However, the common-mode inductor may not play any role in reducing the low-frequency common-mode voltage generated by the diode rectifier, so that a low-frequency component still remains in the shaft voltage. Such a low-frequency shaft voltage may not produce any bad effect on motor bearings. The validity and effectiveness of the EMI filter is verified by experimental results obtained from a 200-V 5-kVA laboratory system.

  10. Hierarchical cellular materials

    SciTech Connect

    Gibson, L.J.

    1991-12-31

    In this paper a method for estimating the contributions of both the composite and the cellular microstructures to the overall material properties and the mechanical efficiency of natural cellular solids will be described. The method will be demonstrated by focusing on the Young`s modulus; similar techniques can be used for other material properties. The results suggest efficient microstructures for engineered cellular materials.

  11. Hierarchical cellular materials

    SciTech Connect

    Gibson, L.J.

    1991-01-01

    In this paper a method for estimating the contributions of both the composite and the cellular microstructures to the overall material properties and the mechanical efficiency of natural cellular solids will be described. The method will be demonstrated by focusing on the Young's modulus; similar techniques can be used for other material properties. The results suggest efficient microstructures for engineered cellular materials.

  12. Xtoys: Cellular automata on xwindows

    SciTech Connect

    Creutz, M.

    1995-08-15

    Xtoys is a collection of xwindow programs for demonstrating simulations of various statistical models. Included are xising, for the two dimensional Ising model, xpotts, for the q-state Potts model, xautomalab, for a fairly general class of totalistic cellular automata, xsand, for the Bak-Tang-Wiesenfield model of self organized criticality, and xfires, a simple forest fire simulation. The programs should compile on any machine supporting xwindows.

  13. 48 CFR 1501.101 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Purpose. 1501.101 Section 1501.101 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY GENERAL GENERAL Purpose, Authority, Issuance 1501.101 Purpose. This subpart establishes Chapter 15, the Environmental...

  14. 29 CFR 784.0 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Purpose. 784.0 Section 784.0 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR... FISHING AND OPERATIONS ON AQUATIC PRODUCTS General Introductory § 784.0 Purpose. It is the purpose of...

  15. 23 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Purpose. 1.1 Section 1.1 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GENERAL MANAGEMENT AND ADMINISTRATION GENERAL § 1.1 Purpose. The purpose of the regulations in this part is to implement and carry out the provisions of Federal...

  16. 23 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Purpose. 1.1 Section 1.1 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GENERAL MANAGEMENT AND ADMINISTRATION GENERAL § 1.1 Purpose. The purpose of the regulations in this part is to implement and carry out the provisions of Federal...

  17. 23 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Purpose. 1.1 Section 1.1 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GENERAL MANAGEMENT AND ADMINISTRATION GENERAL § 1.1 Purpose. The purpose of the regulations in this part is to implement and carry out the provisions of Federal...

  18. 23 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Purpose. 1.1 Section 1.1 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GENERAL MANAGEMENT AND ADMINISTRATION GENERAL § 1.1 Purpose. The purpose of the regulations in this part is to implement and carry out the provisions of Federal...

  19. 23 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Purpose. 1.1 Section 1.1 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GENERAL MANAGEMENT AND ADMINISTRATION GENERAL § 1.1 Purpose. The purpose of the regulations in this part is to implement and carry out the provisions of Federal...

  20. Cellular Manufacturing Internet Performance Support System

    SciTech Connect

    Bohley, M.C.; Schwartz, M.E.

    1998-03-04

    The objective of this project was to develop an Internet-based electronic performance support system (EPSS) for cellular manufacturing providing hardware/software specifications, process descriptions, estimated cost savings, manufacturing simulations, training information, and service resources for government and industry users of Cincinnati Milacron machine tools and products. AlliedSignal Federal Manufacturing and Technologies (ASFM and T) used expertise in the areas of Internet design and multimedia creation to develop a performance support system (PSS) for the Internet with assistance from CM's subject matter experts from engineering, manufacturing, and technical support. Reference information was both created and re-purposed from other existing formats, then made available on the Internet. On-line references on cellular manufacturing operations include: definitions of cells and cellular manufacturing; illustrations on how cellular manufacturing improves part throughput, resource utilization, part quality, and manufacturing flexibility; illustrations on how cellular manufacturing reduces labor and overhead costs; identification of critical factors driving decisions toward cellular manufacturing; a method for identifying process improvement areas using cellular manufacturing; a method for customizing the size of cells for a specific site; a simulation for making a part using cellular manufacturing technology; and a glossary of terms and concepts.

  1. Local unitary quantum cellular automata

    SciTech Connect

    Perez-Delgado, Carlos A.; Cheung, Donny

    2007-09-15

    In this paper we present a quantization of cellular automata. Our formalism is based on a lattice of qudits and an update rule consisting of local unitary operators that commute with their own lattice translations. One purpose of this model is to act as a theoretical model of quantum computation, similar to the quantum circuit model. It is also shown to be an appropriate abstraction for space-homogeneous quantum phenomena, such as quantum lattice gases, spin chains, and others. Some results that show the benefits of basing the model on local unitary operators are shown: universality, strong connections to the circuit model, simple implementation on quantum hardware, and a wealth of applications.

  2. Hijacking cellular garbage cans.

    PubMed

    Welsch, Sonja; Locker, Jacomine Krijnse

    2010-06-25

    Viruses are perfect opportunists that have evolved to modify numerous cellular processes in order to complete their replication cycle in the host cell. An article by Reggiori and coworkers in this issue of Cell Host & Microbe reveals how coronaviruses can divert a cellular quality control pathway that normally functions in degradation of mis-folded proteins to replicate the viral genome. PMID:20542246

  3. 48 CFR 2301.101 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 2301.101 Federal Acquisition Regulations System SOCIAL SECURITY ADMINISTRATION GENERAL SOCIAL SECURITY ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance 2301.101 Purpose. (a) The Social Security Acquisition Regulation (SSAR) is issued to establish uniform acquisition policies and procedures for...

  4. 21 CFR 1140.2 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... CIGARETTES AND SMOKELESS TOBACCO General Provisions § 1140.2 Purpose. The purpose of this part is to establish restrictions on the sale, distribution, and use of cigarettes and smokeless tobacco in order...

  5. 21 CFR 1140.2 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... CIGARETTES AND SMOKELESS TOBACCO General Provisions § 1140.2 Purpose. The purpose of this part is to establish restrictions on the sale, distribution, and use of cigarettes and smokeless tobacco in order...

  6. 21 CFR 1140.2 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... CIGARETTES AND SMOKELESS TOBACCO General Provisions § 1140.2 Purpose. The purpose of this part is to establish restrictions on the sale, distribution, and use of cigarettes and smokeless tobacco in order...

  7. 30 CFR 256.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and Sulphur Management, General § 256.1 Purpose. The purpose of the regulations in 30 CFR part 256 is to establish the...

  8. 30 CFR 256.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and Sulphur Management, General § 256.1 Purpose. The purpose of the regulations in 30 CFR part 256 is to establish the...

  9. 28 CFR 42.501 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the Rehabilitation Act of 1973 General Provisions § 42.501 Purpose. The purpose of this subpart is to implement section 504 of the Rehabilitation Act of 1973, as amended, which prohibits discrimination on...

  10. 28 CFR 42.501 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the Rehabilitation Act of 1973 General Provisions § 42.501 Purpose. The purpose of this subpart is to implement section 504 of the Rehabilitation Act of 1973, as amended, which prohibits discrimination on...

  11. 28 CFR 42.501 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the Rehabilitation Act of 1973 General Provisions § 42.501 Purpose. The purpose of this subpart is to implement section 504 of the Rehabilitation Act of 1973, as amended, which prohibits discrimination on...

  12. 28 CFR 42.501 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the Rehabilitation Act of 1973 General Provisions § 42.501 Purpose. The purpose of this subpart is to implement section 504 of the Rehabilitation Act of 1973, as amended, which prohibits discrimination on...

  13. 28 CFR 42.501 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the Rehabilitation Act of 1973 General Provisions § 42.501 Purpose. The purpose of this subpart is to implement section 504 of the Rehabilitation Act of 1973, as amended, which prohibits discrimination on...

  14. 48 CFR 901.101 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 901.101 Federal Acquisition Regulations System DEPARTMENT OF ENERGY GENERAL FEDERAL ACQUISITION REGULATIONS SYSTEM Purpose, Authority, Issuance 901.101 Purpose. The Department of Energy Acquisition Regulation (DEAR) in this chapter establishes uniform acquisition policies which implement and supplement...

  15. 43 CFR 2520.0-1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) DESERT-LAND ENTRIES Desert-Land Entries: General § 2520.0-1 Purpose. (a) It is the purpose of the statutes governing desert-land entries to encourage...

  16. 43 CFR 2520.0-1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) DESERT-LAND ENTRIES Desert-Land Entries: General § 2520.0-1 Purpose. (a) It is the purpose of the statutes governing desert-land entries to encourage...

  17. 43 CFR 2520.0-1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) DESERT-LAND ENTRIES Desert-Land Entries: General § 2520.0-1 Purpose. (a) It is the purpose of the statutes governing desert-land entries to encourage...

  18. 43 CFR 2520.0-1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) DESERT-LAND ENTRIES Desert-Land Entries: General § 2520.0-1 Purpose. (a) It is the purpose of the statutes governing desert-land entries to encourage...

  19. 12 CFR 1805.100 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS PROGRAM General Provisions § 1805.100 Purpose. The purpose of the Community Development Financial Institutions Program is to promote economic revitalization and community...

  20. 30 CFR 256.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and Sulphur Management, General § 256.1 Purpose. The purpose of the regulations in 30 CFR part 256 is to establish the...

  1. 32 CFR 935.2 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CODE General § 935.2 Purpose. The purpose of this part is to provide— (a) For the civil administration of Wake Island; (b) Civil laws for Wake Island not otherwise provided for; (c) Criminal laws for...

  2. 49 CFR 272.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... TRANSPORTATION CRITICAL INCIDENT STRESS PLANS General § 272.1 Purpose. (a) The purpose of this part is to promote... critical incident stress plan that contains additional provisions beyond those specified in this...

  3. 28 CFR 91.50 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Procedures for VOI/TIS Grant Program In General § 91.50 Purpose. The purpose of this subpart is to inform grant recipients under the Violent Offender Incarceration and Truth-in-Sentencing Incentive...

  4. Cellular Reflectarray Antenna

    NASA Technical Reports Server (NTRS)

    Romanofsky, Robert R.

    2010-01-01

    The cellular reflectarray antenna is intended to replace conventional parabolic reflectors that must be physically aligned with a particular satellite in geostationary orbit. These arrays are designed for specified geographical locations, defined by latitude and longitude, each called a "cell." A particular cell occupies nominally 1,500 square miles (3,885 sq. km), but this varies according to latitude and longitude. The cellular reflectarray antenna designed for a particular cell is simply positioned to align with magnetic North, and the antenna surface is level (parallel to the ground). A given cellular reflectarray antenna will not operate in any other cell.

  5. 5 CFR 330.701 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... PLACEMENT (GENERAL) Interagency Career Transition Assistance Plan for Displaced Employees § 330.701 Purpose... interagency career transition assistance program for Federal employees during a period of severe...

  6. [Main Cellular Redox Couples].

    PubMed

    Bilan, D S; Shokhina, A G; Lukyanov, S A; Belousov, V V

    2015-01-01

    Most of the living cells maintain the continuous flow of electrons, which provides them by energy. Many of the compounds are presented in a cell at the same time in the oxidized and reduced states, forming the active redox couples. Some of the redox couples, such as NAD+/NADH, NADP+/NADPH, oxidized/reduced glutathione (GSSG/GSH), are universal, as they participate in adjusting of many cellular reactions. Ratios of the oxidized and reduced forms of these compounds are important cellular redox parameters. Modern research approaches allow setting the new functions of the main redox couples in the complex organization of cellular processes. The following information is about the main cellular redox couples and their participation in various biological processes.

  7. Nanostructured cellular networks.

    PubMed

    Moriarty, P; Taylor, M D R; Brust, M

    2002-12-01

    Au nanocrystals spin-coated onto silicon from toluene form cellular networks. A quantitative statistical crystallography analysis shows that intercellular correlations drive the networks far from statistical equilibrium. Spin-coating from hexane does not produce cellular structure, yet a strong correlation is retained in the positions of nanocrystal aggregates. Mechanisms based on Marangoni convection alone cannot account for the variety of patterns observed, and we argue that spinodal decomposition plays an important role in foam formation.

  8. 7 CFR 622.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AGRICULTURE WATER RESOURCES WATERSHED PROJECTS General § 622.1 Purpose. This part sets forth the general policies for planning and carrying out watershed projects under Pub. L. 83-566, 68 Stat. 666 (16...

  9. 7 CFR 622.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AGRICULTURE WATER RESOURCES WATERSHED PROJECTS General § 622.1 Purpose. This part sets forth the general policies for planning and carrying out watershed projects under Pub. L. 83-566, 68 Stat. 666 (16...

  10. 7 CFR 622.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AGRICULTURE WATER RESOURCES WATERSHED PROJECTS General § 622.1 Purpose. This part sets forth the general policies for planning and carrying out watershed projects under Pub. L. 83-566, 68 Stat. 666 (16...

  11. 7 CFR 622.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AGRICULTURE WATER RESOURCES WATERSHED PROJECTS General § 622.1 Purpose. This part sets forth the general policies for planning and carrying out watershed projects under Pub. L. 83-566, 68 Stat. 666 (16...

  12. 7 CFR 622.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AGRICULTURE WATER RESOURCES WATERSHED PROJECTS General § 622.1 Purpose. This part sets forth the general policies for planning and carrying out watershed projects under Pub. L. 83-566, 68 Stat. 666 (16...

  13. 33 CFR 135.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION COMPENSATION FUND General § 135.1 Purpose... oil pollution liability and compensation, including the administration and general operation of...

  14. 33 CFR 135.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION COMPENSATION FUND General § 135.1 Purpose... oil pollution liability and compensation, including the administration and general operation of...

  15. 33 CFR 135.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION COMPENSATION FUND General § 135.1 Purpose... oil pollution liability and compensation, including the administration and general operation of...

  16. 33 CFR 135.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION COMPENSATION FUND General § 135.1 Purpose... oil pollution liability and compensation, including the administration and general operation of...

  17. 33 CFR 135.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION COMPENSATION FUND General § 135.1 Purpose... oil pollution liability and compensation, including the administration and general operation of...

  18. Cellular aging and cancer

    PubMed Central

    Hornsby, Peter J.

    2010-01-01

    Aging is manifest in a variety of changes over time, including changes at the cellular level. Cellular aging acts primarily as a tumor suppressor mechanism, but also may enhance cancer development under certain circumstances. One important process of cellular aging is oncogene-induced senescence, which acts as an important anti-cancer mechanism. Cellular senescence resulting from damage caused by activated oncogenes prevents the growth or potentially neoplastic cells. Moreover, cells that have entered senescence appear to be targets for elimination by the innnate immune system. In another aspect of cellular aging, the absence of telomerase activity in normal tissues results in such cells lacking a telomere maintenance mechanism. One consequence is that in aging there is an increase in cells with shortened telomeres. In the presence of active oncogenes that cause expansion of a neoplastic clone, shortening of telomeres leading to telomere dysfunction prevents the indefinite expansion of the clone because the cells enter crisis. Crisis results from fusions and other defects caused by dysfunctional telomeres and is a terminal state of the neoplastic clone. In this way the absence of telomerase in human cells, while one cause of cellular aging, also acts as an anti-cancer mechanism. PMID:20705476

  19. The Roles of Cellular Nanomechanics in Cancer

    PubMed Central

    Yallapu, Murali M.; Katti, Kalpana S.; Katti, Dinesh R.; Mishra, Sanjay R.; Khan, Sheema; Jaggi, Meena; Chauhan, Subhash C.

    2014-01-01

    The biomechanical properties of cells and tissues may be instrumental in increasing our understanding of cellular behavior and cellular manifestations of diseases such as cancer. Nanomechanical properties can offer clinical translation of therapies beyond what are currently employed. Nanomechanical properties, often measured by nanoindentation methods using atomic force microscopy, may identify morphological variations, cellular binding forces, and surface adhesion behaviors that efficiently differentiate normal cells and cancer cells. The aim of this review is to examine current research involving the general use of atomic force microscopy/nanoindentation in measuring cellular nanomechanics; various factors and instrumental conditions that influence the nanomechanical properties of cells; and implementation of nanoindentation methods to distinguish cancer cells from normal cells or tissues. Applying these fundamental nanomechanical properties to current discoveries in clinical treatment may result in greater efficiency in diagnosis, treatment, and prevention of cancer, which ultimately can change the lives of patients. PMID:25137233

  20. 10 CFR 1046.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... (GENERAL PROVISIONS) PHYSICAL PROTECTION OF SECURITY INTERESTS General § 1046.1 Purpose. The purpose of this part is to set forth Department of Energy, hereinafter “DOE,” security policies and procedures regarding the physical protection of security interests....

  1. 10 CFR 1046.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (GENERAL PROVISIONS) PHYSICAL PROTECTION OF SECURITY INTERESTS General § 1046.1 Purpose. The purpose of this part is to set forth Department of Energy, hereinafter “DOE,” security policies and procedures regarding the physical protection of security interests....

  2. 47 CFR 10.2 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Purpose. 10.2 Section 10.2 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL WIRELESS EMERGENCY ALERTS General Information § 10.2 Purpose. The rules in this part establish the requirements for participation in the voluntary...

  3. 47 CFR 10.2 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Purpose. 10.2 Section 10.2 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL WIRELESS EMERGENCY ALERTS General Information § 10.2 Purpose. The rules in this part establish the requirements for participation in the voluntary...

  4. 10 CFR 1046.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... (GENERAL PROVISIONS) PHYSICAL PROTECTION OF SECURITY INTERESTS General § 1046.1 Purpose. The purpose of this part is to set forth Department of Energy, hereinafter “DOE,” security policies and procedures regarding the physical protection of security interests....

  5. 10 CFR 1046.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... (GENERAL PROVISIONS) PHYSICAL PROTECTION OF SECURITY INTERESTS General § 1046.1 Purpose. The purpose of this part is to set forth Department of Energy, hereinafter “DOE,” security policies and procedures regarding the physical protection of security interests....

  6. 10 CFR 1046.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... (GENERAL PROVISIONS) PHYSICAL PROTECTION OF SECURITY INTERESTS (Eff. until 3-10-14) General § 1046.1 Purpose. The purpose of this part is to set forth Department of Energy, hereinafter “DOE,” security policies and procedures regarding the physical protection of security interests....

  7. 47 CFR 11.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Purpose. 11.1 Section 11.1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL EMERGENCY ALERT SYSTEM (EAS) General § 11.1 Purpose. This part contains rules and regulations providing for an Emergency Alert System (EAS). The EAS provides the President with the capability to...

  8. 47 CFR 11.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Purpose. 11.1 Section 11.1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL EMERGENCY ALERT SYSTEM (EAS) General § 11.1 Purpose. This part contains rules and regulations providing for an Emergency Alert System (EAS). The EAS provides the President with the capability to...

  9. 33 CFR 101.100 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MARITIME SECURITY MARITIME SECURITY: GENERAL General § 101.100 Purpose. (a) The purpose of this subchapter is: (1) To implement portions of the maritime security regime required by the Maritime Transportation Security Act of 2002,...

  10. 45 CFR 1156.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Regulations Relating to Public Welfare (Continued) NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES NATIONAL ENDOWMENT FOR THE ARTS NONDISCRIMINATION ON THE BASIS OF AGE General § 1156.1 Purpose. The purpose of this... general age discrimination regulations at 45 CFR part 90. The Age Discrimination Act of 1975, as...

  11. 44 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... implementation of paragraph (a) is contained in 44 CFR part 5, subpart B. (c) This part contains policies and... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Purpose. 1.1 Section 1.1... GENERAL RULEMAKING; POLICY AND PROCEDURES General § 1.1 Purpose. (a) This part contains the basic...

  12. 44 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... implementation of paragraph (a) is contained in 44 CFR part 5, subpart B. (c) This part contains policies and... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Purpose. 1.1 Section 1.1... GENERAL RULEMAKING; POLICY AND PROCEDURES General § 1.1 Purpose. (a) This part contains the basic...

  13. 44 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... implementation of paragraph (a) is contained in 44 CFR part 5, subpart B. (c) This part contains policies and... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Purpose. 1.1 Section 1.1... GENERAL RULEMAKING; POLICY AND PROCEDURES General § 1.1 Purpose. (a) This part contains the basic...

  14. 21 CFR 203.2 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL PRESCRIPTION DRUG MARKETING General Provisions § 203.2 Purpose. The purpose of this part is to implement the Prescription Drug Marketing Act of 1987 and the Prescription Drug Amendments of 1992, except for those...

  15. 18 CFR 3a.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Purpose. 3a.1 Section 3a.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES NATIONAL SECURITY INFORMATION General § 3a.1 Purpose. This part 3a describes...

  16. 18 CFR 3a.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Purpose. 3a.1 Section 3a.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES NATIONAL SECURITY INFORMATION General § 3a.1 Purpose. This part 3a describes...

  17. 18 CFR 3a.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Purpose. 3a.1 Section 3a.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES NATIONAL SECURITY INFORMATION General § 3a.1 Purpose. This part 3a describes...

  18. 18 CFR 3a.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Purpose. 3a.1 Section 3a.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES NATIONAL SECURITY INFORMATION General § 3a.1 Purpose. This part 3a describes...

  19. 18 CFR 3a.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Purpose. 3a.1 Section 3a.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES NATIONAL SECURITY INFORMATION General § 3a.1 Purpose. This part 3a describes...

  20. 44 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... implementation of paragraph (a) is contained in 44 CFR part 5, subpart B. (c) This part contains policies and... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Purpose. 1.1 Section 1.1... GENERAL RULEMAKING; POLICY AND PROCEDURES General § 1.1 Purpose. (a) This part contains the basic...

  1. 49 CFR 450.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 6 2011-10-01 2011-10-01 false Purpose. 450.1 Section 450.1 Transportation Other Regulations Relating to Transportation (Continued) COAST GUARD, DEPARTMENT OF HOMELAND SECURITY SAFETY APPROVAL OF CARGO CONTAINERS GENERAL General Provisions § 450.1 Purpose. This subchapter establishes requirements and procedures for...

  2. 25 CFR 175.2 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Purpose. 175.2 Section 175.2 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN ELECTRIC POWER UTILITIES General Provisions § 175.2 Purpose. The purpose of this part is to regulate the electric power utilities administered...

  3. 25 CFR 175.2 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Purpose. 175.2 Section 175.2 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN ELECTRIC POWER UTILITIES General Provisions § 175.2 Purpose. The purpose of this part is to regulate the electric power utilities administered...

  4. 25 CFR 175.2 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Purpose. 175.2 Section 175.2 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN ELECTRIC POWER UTILITIES General Provisions § 175.2 Purpose. The purpose of this part is to regulate the electric power utilities administered...

  5. 25 CFR 175.2 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Purpose. 175.2 Section 175.2 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN ELECTRIC POWER UTILITIES General Provisions § 175.2 Purpose. The purpose of this part is to regulate the electric power utilities administered...

  6. 25 CFR 175.2 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Purpose. 175.2 Section 175.2 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN ELECTRIC POWER UTILITIES General Provisions § 175.2 Purpose. The purpose of this part is to regulate the electric power utilities administered...

  7. 48 CFR 2801.101 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Purpose. 2801.101 Section 2801.101 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE General DEPARTMENT OF JUSTICE ACQUISITION REGULATIONS SYSTEM Purpose, Authority, Issuance 2801.101 Purpose. (a) The Justice...

  8. 10 CFR 706.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Purpose. 706.1 Section 706.1 Energy DEPARTMENT OF ENERGY SECURITY POLICIES AND PRACTICES RELATING TO LABOR-MANAGEMENT RELATIONS General § 706.1 Purpose. The purpose of this part is to set forth Department of Energy, hereinafter “DOE,” security policies and...

  9. 10 CFR 706.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Purpose. 706.1 Section 706.1 Energy DEPARTMENT OF ENERGY SECURITY POLICIES AND PRACTICES RELATING TO LABOR-MANAGEMENT RELATIONS General § 706.1 Purpose. The purpose of this part is to set forth Department of Energy, hereinafter “DOE,” security policies and...

  10. 14 CFR 1201.101 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Purpose. 1201.101 Section 1201.101 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION STATEMENT OF ORGANIZATION AND GENERAL INFORMATION Introduction § 1201.101 Purpose. It is the purpose of the National Aeronautics and...

  11. 14 CFR 1201.101 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Purpose. 1201.101 Section 1201.101 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION STATEMENT OF ORGANIZATION AND GENERAL INFORMATION Introduction § 1201.101 Purpose. It is the purpose of the National Aeronautics and...

  12. 14 CFR § 1201.101 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Purpose. § 1201.101 Section § 1201.101 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION STATEMENT OF ORGANIZATION AND GENERAL INFORMATION Introduction § 1201.101 Purpose. It is the purpose of the National Aeronautics and...

  13. 14 CFR 1201.101 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Purpose. 1201.101 Section 1201.101 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION STATEMENT OF ORGANIZATION AND GENERAL INFORMATION Introduction § 1201.101 Purpose. It is the purpose of the National Aeronautics and...

  14. 10 CFR 706.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Purpose. 706.1 Section 706.1 Energy DEPARTMENT OF ENERGY SECURITY POLICIES AND PRACTICES RELATING TO LABOR-MANAGEMENT RELATIONS General § 706.1 Purpose. The purpose of this part is to set forth Department of Energy, hereinafter “DOE,” security policies and...

  15. 10 CFR 706.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Purpose. 706.1 Section 706.1 Energy DEPARTMENT OF ENERGY SECURITY POLICIES AND PRACTICES RELATING TO LABOR-MANAGEMENT RELATIONS General § 706.1 Purpose. The purpose of this part is to set forth Department of Energy, hereinafter “DOE,” security policies and...

  16. 10 CFR 706.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Purpose. 706.1 Section 706.1 Energy DEPARTMENT OF ENERGY SECURITY POLICIES AND PRACTICES RELATING TO LABOR-MANAGEMENT RELATIONS General § 706.1 Purpose. The purpose of this part is to set forth Department of Energy, hereinafter “DOE,” security policies and...

  17. 46 CFR 62.01-1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Purpose. 62.01-1 Section 62.01-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING VITAL SYSTEM AUTOMATION General Provisions § 62.01-1 Purpose. The purpose of this part is to make sure that the safety of a vessel with...

  18. 46 CFR 62.01-1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Purpose. 62.01-1 Section 62.01-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING VITAL SYSTEM AUTOMATION General Provisions § 62.01-1 Purpose. The purpose of this part is to make sure that the safety of a vessel with...

  19. 45 CFR 51.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Purpose. 51.1 Section 51.1 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CRITERIA FOR EVALUATING COMPREHENSIVE PLAN TO REDUCE RELIANCE ON ALIEN PHYSICIANS § 51.1 Purpose. The purpose of this regulation is to...

  20. 23 CFR 810.2 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Purpose. 810.2 Section 810.2 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PUBLIC TRANSPORTATION MASS TRANSIT AND SPECIAL USE HIGHWAY PROJECTS General § 810.2 Purpose. The purpose of this regulation is to implement sections 137, 142, and 149...

  1. 31 CFR 129.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Purpose. 129.1 Section 129.1 Money and Finance: Treasury Regulations Relating to Money and Finance PORTFOLIO INVESTMENT SURVEY REPORTING § 129.1 Purpose. The purpose of this part is to provide general information on portfolio...

  2. 47 CFR 8.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Purpose. 8.1 Section 8.1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRESERVING THE OPEN INTERNET § 8.1 Purpose. The purpose of this part is to preserve the Internet as an open platform enabling consumer choice, freedom of...

  3. 47 CFR 8.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Purpose. 8.1 Section 8.1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRESERVING THE OPEN INTERNET § 8.1 Purpose. The purpose of this part is to preserve the Internet as an open platform enabling consumer choice, freedom of...

  4. 47 CFR 8.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Purpose. 8.1 Section 8.1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRESERVING THE OPEN INTERNET § 8.1 Purpose. The purpose of this part is to preserve the Internet as an open platform enabling consumer choice, freedom of...

  5. 47 CFR 8.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Purpose. 8.1 Section 8.1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRESERVING THE OPEN INTERNET § 8.1 Purpose. The purpose of this part is to preserve the Internet as an open platform enabling consumer choice, freedom of...

  6. 7 CFR 22.103 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Purpose. 22.103 Section 22.103 Agriculture Office of the Secretary of Agriculture RURAL DEVELOPMENT COORDINATION General § 22.103 Purpose. The purpose of... of the Rural Development Act....

  7. 46 CFR 401.100 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Purpose. 401.100 Section 401.100 Shipping COAST GUARD (GREAT LAKES PILOTAGE), DEPARTMENT OF HOMELAND SECURITY GREAT LAKES PILOTAGE REGULATIONS General § 401.100 Purpose. The purpose of this part is to carry out those provisions of the Great Lakes Pilotage...

  8. 46 CFR 402.100 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Purpose. 402.100 Section 402.100 Shipping COAST GUARD (GREAT LAKES PILOTAGE), DEPARTMENT OF HOMELAND SECURITY GREAT LAKES PILOTAGE RULES AND ORDERS General § 402.100 Purpose. The purpose of this part is to implement those provisions of the Great Lakes...

  9. 6 CFR 27.100 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 6 Domestic Security 1 2013-01-01 2013-01-01 false Purpose. 27.100 Section 27.100 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS General § 27.100 Purpose. The purpose of this part is to enhance the security of our Nation by furthering...

  10. 6 CFR 27.100 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 6 Domestic Security 1 2011-01-01 2011-01-01 false Purpose. 27.100 Section 27.100 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS General § 27.100 Purpose. The purpose of this part is to enhance the security of our Nation by furthering...

  11. 6 CFR 27.100 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 6 Domestic Security 1 2012-01-01 2012-01-01 false Purpose. 27.100 Section 27.100 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS General § 27.100 Purpose. The purpose of this part is to enhance the security of our Nation by furthering...

  12. 6 CFR 27.100 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 6 Domestic Security 1 2014-01-01 2014-01-01 false Purpose. 27.100 Section 27.100 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS General § 27.100 Purpose. The purpose of this part is to enhance the security of our Nation by furthering...

  13. 44 CFR 206.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...). The rules in this subpart apply to major disasters and emergencies declared by the President on or after November 23, 1988, the date of enactment of the Robert T. Stafford Disaster Relief and Emergency... DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE General § 206.1 Purpose. (a) Purpose. The purpose of...

  14. 49 CFR 37.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Purpose. 37.1 Section 37.1 Transportation Office of the Secretary of Transportation TRANSPORTATION SERVICES FOR INDIVIDUALS WITH DISABILITIES (ADA) General § 37.1 Purpose. The purpose of this part is to implement the transportation and related...

  15. 23 CFR 810.2 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Purpose. 810.2 Section 810.2 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PUBLIC TRANSPORTATION MASS TRANSIT AND SPECIAL USE HIGHWAY PROJECTS General § 810.2 Purpose. The purpose of this regulation is to implement sections 137, 142, and 149...

  16. 23 CFR 810.2 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Purpose. 810.2 Section 810.2 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PUBLIC TRANSPORTATION MASS TRANSIT AND SPECIAL USE HIGHWAY PROJECTS General § 810.2 Purpose. The purpose of this regulation is to implement sections 137, 142, and 149...

  17. 23 CFR 810.2 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Purpose. 810.2 Section 810.2 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PUBLIC TRANSPORTATION MASS TRANSIT AND SPECIAL USE HIGHWAY PROJECTS General § 810.2 Purpose. The purpose of this regulation is to implement sections 137, 142, and 149...

  18. 25 CFR 700.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false Purpose. 700.1 Section 700.1 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions § 700.1 Purpose. The purpose of this part is to implement provisions of the Act of December...

  19. 25 CFR 700.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false Purpose. 700.1 Section 700.1 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions § 700.1 Purpose. The purpose of this part is to implement provisions of the Act of December...

  20. 25 CFR 700.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false Purpose. 700.1 Section 700.1 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions § 700.1 Purpose. The purpose of this part is to implement provisions of the Act of December...

  1. 46 CFR 111.51-1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Purpose. 111.51-1 Section 111.51-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Coordination of Overcurrent Protective Devices § 111.51-1 Purpose. The purpose of this subpart is to...

  2. 46 CFR 111.51-1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Purpose. 111.51-1 Section 111.51-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Coordination of Overcurrent Protective Devices § 111.51-1 Purpose. The purpose of this subpart is to...

  3. 14 CFR 1201.101 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Purpose. 1201.101 Section 1201.101 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION STATEMENT OF ORGANIZATION AND GENERAL INFORMATION Introduction § 1201.101 Purpose. It is the purpose of the National Aeronautics and...

  4. 46 CFR 154.3 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Purpose. 154.3 Section 154.3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.3 Purpose. The purpose of this part is...

  5. 28 CFR 20.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Purpose. 20.1 Section 20.1 Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL JUSTICE INFORMATION SYSTEMS General Provisions § 20.1 Purpose. It is the purpose of these regulations to assure that criminal history record information wherever...

  6. 28 CFR 20.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Purpose. 20.1 Section 20.1 Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL JUSTICE INFORMATION SYSTEMS General Provisions § 20.1 Purpose. It is the purpose of these regulations to assure that criminal history record information wherever...

  7. 28 CFR 20.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Purpose. 20.1 Section 20.1 Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL JUSTICE INFORMATION SYSTEMS General Provisions § 20.1 Purpose. It is the purpose of these regulations to assure that criminal history record information wherever...

  8. 28 CFR 20.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Purpose. 20.1 Section 20.1 Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL JUSTICE INFORMATION SYSTEMS General Provisions § 20.1 Purpose. It is the purpose of these regulations to assure that criminal history record information wherever...

  9. 12 CFR 1807.100 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 9 2012-01-01 2012-01-01 false Purpose. 1807.100 Section 1807.100 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY CAPITAL MAGNET FUND General Provisions § 1807.100 Purpose. The purpose of the Capital Magnet Fund (CMF) is to attract...

  10. 12 CFR 1807.100 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Purpose. 1807.100 Section 1807.100 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY CAPITAL MAGNET FUND General Provisions § 1807.100 Purpose. The purpose of the Capital Magnet Fund (CMF) is to attract...

  11. 12 CFR 1807.100 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 7 2011-01-01 2011-01-01 false Purpose. 1807.100 Section 1807.100 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY CAPITAL MAGNET FUND General Provisions § 1807.100 Purpose. The purpose of the Capital Magnet Fund (CMF) is to attract...

  12. 12 CFR 1807.100 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 9 2013-01-01 2013-01-01 false Purpose. 1807.100 Section 1807.100 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY CAPITAL MAGNET FUND General Provisions § 1807.100 Purpose. The purpose of the Capital Magnet Fund (CMF) is to attract...

  13. 46 CFR 111.51-1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Purpose. 111.51-1 Section 111.51-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Coordination of Overcurrent Protective Devices § 111.51-1 Purpose. The purpose of this subpart is to...

  14. 46 CFR 111.51-1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Purpose. 111.51-1 Section 111.51-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Coordination of Overcurrent Protective Devices § 111.51-1 Purpose. The purpose of this subpart is to...

  15. 43 CFR 37.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Purpose. 37.1 Section 37.1 Public Lands: Interior Office of the Secretary of the Interior CAVE MANAGEMENT Cave Management-General § 37.1 Purpose. The purpose of this part is to provide the basis for identifying and managing significant caves...

  16. 43 CFR 37.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true Purpose. 37.1 Section 37.1 Public Lands: Interior Office of the Secretary of the Interior CAVE MANAGEMENT Cave Management-General § 37.1 Purpose. The purpose of this part is to provide the basis for identifying and managing significant caves...

  17. 43 CFR 37.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 1 2013-10-01 2013-10-01 false Purpose. 37.1 Section 37.1 Public Lands: Interior Office of the Secretary of the Interior CAVE MANAGEMENT Cave Management-General § 37.1 Purpose. The purpose of this part is to provide the basis for identifying and managing significant caves...

  18. 43 CFR 37.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false Purpose. 37.1 Section 37.1 Public Lands: Interior Office of the Secretary of the Interior CAVE MANAGEMENT Cave Management-General § 37.1 Purpose. The purpose of this part is to provide the basis for identifying and managing significant caves...

  19. 43 CFR 37.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Purpose. 37.1 Section 37.1 Public Lands: Interior Office of the Secretary of the Interior CAVE MANAGEMENT Cave Management-General § 37.1 Purpose. The purpose of this part is to provide the basis for identifying and managing significant caves...

  20. 6 CFR 27.100 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Purpose. 27.100 Section 27.100 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS General § 27.100 Purpose. The purpose of this Part is to enhance the security of our Nation by furthering...

  1. 23 CFR 810.2 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Purpose. 810.2 Section 810.2 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PUBLIC TRANSPORTATION MASS TRANSIT AND SPECIAL USE HIGHWAY PROJECTS General § 810.2 Purpose. The purpose of this regulation is to implement sections 137, 142, and 149...

  2. Benchmark study between FIDAP and a cellular automata code

    NASA Astrophysics Data System (ADS)

    Akau, R. L.; Stockman, H. W.

    A fluid flow benchmark exercise was conducted to compare results between a cellular automata code and FIDAP. Cellular automata codes are free from gridding constraints, and are generally used to model slow (Reynolds number approximately 1) flows around complex solid obstacles. However, the accuracy of cellular automata codes at higher Reynolds numbers, where inertial terms are significant, is not well-documented. In order to validate the cellular automata code, two fluids problems were investigated. For both problems, flow was assumed to be laminar, two-dimensional, isothermal, incompressible and periodic. Results showed that the cellular automata code simulated the overall behavior of the flow field.

  3. Teen Perceptions of Cellular Phones as a Communication Tool

    ERIC Educational Resources Information Center

    Jonas, Denise D.

    2011-01-01

    The excitement and interest in innovative technologies has spanned centuries. However, the invention of the cellular phone has surpassed previous technology interests, and changed the way we communicate today. Teens make up the fastest growing market of current cellular phone users. Consequently, the purpose of this study was to determine teen…

  4. Origins of cellular geometry

    PubMed Central

    2011-01-01

    Cells are highly complex and orderly machines, with defined shapes and a startling variety of internal organizations. Complex geometry is a feature of both free-living unicellular organisms and cells inside multicellular animals. Where does the geometry of a cell come from? Many of the same questions that arise in developmental biology can also be asked of cells, but in most cases we do not know the answers. How much of cellular organization is dictated by global cell polarity cues as opposed to local interactions between cellular components? Does cellular structure persist across cell generations? What is the relationship between cell geometry and tissue organization? What ensures that intracellular structures are scaled to the overall size of the cell? Cell biology is only now beginning to come to grips with these questions. PMID:21880160

  5. Architected Cellular Materials

    NASA Astrophysics Data System (ADS)

    Schaedler, Tobias A.; Carter, William B.

    2016-07-01

    Additive manufacturing enables fabrication of materials with intricate cellular architecture, whereby progress in 3D printing techniques is increasing the possible configurations of voids and solids ad infinitum. Examples are microlattices with graded porosity and truss structures optimized for specific loading conditions. The cellular architecture determines the mechanical properties and density of these materials and can influence a wide range of other properties, e.g., acoustic, thermal, and biological properties. By combining optimized cellular architectures with high-performance metals and ceramics, several lightweight materials that exhibit strength and stiffness previously unachievable at low densities were recently demonstrated. This review introduces the field of architected materials; summarizes the most common fabrication methods, with an emphasis on additive manufacturing; and discusses recent progress in the development of architected materials. The review also discusses important applications, including lightweight structures, energy absorption, metamaterials, thermal management, and bioscaffolds.

  6. Epigenetics and Cellular Metabolism

    PubMed Central

    Xu, Wenyi; Wang, Fengzhong; Yu, Zhongsheng; Xin, Fengjiao

    2016-01-01

    Living eukaryotic systems evolve delicate cellular mechanisms for responding to various environmental signals. Among them, epigenetic machinery (DNA methylation, histone modifications, microRNAs, etc.) is the hub in transducing external stimuli into transcriptional response. Emerging evidence reveals the concept that epigenetic signatures are essential for the proper maintenance of cellular metabolism. On the other hand, the metabolite, a main environmental input, can also influence the processing of epigenetic memory. Here, we summarize the recent research progress in the epigenetic regulation of cellular metabolism and discuss how the dysfunction of epigenetic machineries influences the development of metabolic disorders such as diabetes and obesity; then, we focus on discussing the notion that manipulating metabolites, the fuel of cell metabolism, can function as a strategy for interfering epigenetic machinery and its related disease progression as well. PMID:27695375

  7. Epigenetics and Cellular Metabolism

    PubMed Central

    Xu, Wenyi; Wang, Fengzhong; Yu, Zhongsheng; Xin, Fengjiao

    2016-01-01

    Living eukaryotic systems evolve delicate cellular mechanisms for responding to various environmental signals. Among them, epigenetic machinery (DNA methylation, histone modifications, microRNAs, etc.) is the hub in transducing external stimuli into transcriptional response. Emerging evidence reveals the concept that epigenetic signatures are essential for the proper maintenance of cellular metabolism. On the other hand, the metabolite, a main environmental input, can also influence the processing of epigenetic memory. Here, we summarize the recent research progress in the epigenetic regulation of cellular metabolism and discuss how the dysfunction of epigenetic machineries influences the development of metabolic disorders such as diabetes and obesity; then, we focus on discussing the notion that manipulating metabolites, the fuel of cell metabolism, can function as a strategy for interfering epigenetic machinery and its related disease progression as well.

  8. Genetic Dominance & Cellular Processes

    ERIC Educational Resources Information Center

    Seager, Robert D.

    2014-01-01

    In learning genetics, many students misunderstand and misinterpret what "dominance" means. Understanding is easier if students realize that dominance is not a mechanism, but rather a consequence of underlying cellular processes. For example, metabolic pathways are often little affected by changes in enzyme concentration. This means that…

  9. The New Cellular Immunology

    ERIC Educational Resources Information Center

    Claman, Henry N.

    1973-01-01

    Discusses the nature of the immune response and traces many of the discoveries that have led to the present state of knowledge in immunology. The new cellular immunology is directing its efforts toward improving health by proper manipulation of the immune mechanisms of the body. (JR)

  10. Fabrication of cellular materials

    NASA Astrophysics Data System (ADS)

    Prud'homme, Robert K.; Aksay, Ilhan A.; Garg, Rajeev

    1996-02-01

    Nature uses cellular materials in applications requiring strength while, simultaneously, minimizing raw materials requirements. Minimizing raw materials is efficient both in terms of the energy expended by the organism to synthesize the structure and in terms of the strength- to-weight ratio of the structure. Wood is the most obvious example of cellular bio-materials, and it is the focus of other presentations in this symposium. The lightweight bone structure of birds is another excellent example where weight is a key criterion. The anchoring foot of the common muscle [Mytilus edulis] whereby it attaches itself to objects is a further example of a biological system that uses a foam to fill space and yet conserve on raw materials. In the case of the muscle the foam is water filled and the foot structure distributes stress over a larger area so that the strength of the byssal thread from which it is suspended is matched to the strength of interfacial attachment of the foot to a substrate. In these examples the synthesis and fabrication of the cellular material is directed by intercellular, genetically coded, biochemical reactions. The resulting cell sizes are microns in scale. Cellular materials at the next larger scale are created by organisms at the next higher level of integration. For example an African tree frog lays her eggs in a gas/fluid foam sack she builds on a branch overhanging a pond. The outside of the foam sack hardens in the sun and prevents water evaporation. The foam structure minimizes the amount of fluid that needs to be incorporated into the sack and minimizes its weight. However, as far as the developing eggs are concerned, they are in an aqueous medium, i.e. the continuous fluid phase of the foam. After precisely six days the eggs hatch, and the solidified outer wall re-liquefies and dumps the emerging tadpoles into the pond below. The bee honeycomb is an example of a cellular material with exquisite periodicity at millimeter length scales. The

  11. 46 CFR 197.200 - Purpose of subpart.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... GENERAL PROVISIONS Commercial Diving Operations General § 197.200 Purpose of subpart. This subpart... and health standards for commercial diving operations taking place from vessels and facilities...

  12. 46 CFR 197.200 - Purpose of subpart.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... GENERAL PROVISIONS Commercial Diving Operations General § 197.200 Purpose of subpart. This subpart... and health standards for commercial diving operations taking place from vessels and facilities...

  13. 47 CFR 11.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... FEDERAL COMMUNICATIONS COMMISSION GENERAL EMERGENCY ALERT SYSTEM (EAS) General § 11.1 Purpose. This part... President with the capability to provide immediate communications and information to the general public at... broadcast stations, digital broadcast stations, analog cable systems, digital cable systems, wireline...

  14. 15 CFR 970.100 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES General § 970.100 Purpose. (a) General... recognition that the deep seabed mining industry is still evolving and that more information must be...

  15. 15 CFR 970.100 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES General § 970.100 Purpose. (a) General... recognition that the deep seabed mining industry is still evolving and that more information must be...

  16. 15 CFR 970.100 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES General § 970.100 Purpose. (a) General... recognition that the deep seabed mining industry is still evolving and that more information must be...

  17. 15 CFR 970.100 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES General § 970.100 Purpose. (a) General... recognition that the deep seabed mining industry is still evolving and that more information must be...

  18. 15 CFR 970.100 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES General § 970.100 Purpose. (a) General... recognition that the deep seabed mining industry is still evolving and that more information must be...

  19. Probabilistic Cellular Automata

    PubMed Central

    Agapie, Alexandru; Giuclea, Marius

    2014-01-01

    Abstract Cellular automata are binary lattices used for modeling complex dynamical systems. The automaton evolves iteratively from one configuration to another, using some local transition rule based on the number of ones in the neighborhood of each cell. With respect to the number of cells allowed to change per iteration, we speak of either synchronous or asynchronous automata. If randomness is involved to some degree in the transition rule, we speak of probabilistic automata, otherwise they are called deterministic. With either type of cellular automaton we are dealing with, the main theoretical challenge stays the same: starting from an arbitrary initial configuration, predict (with highest accuracy) the end configuration. If the automaton is deterministic, the outcome simplifies to one of two configurations, all zeros or all ones. If the automaton is probabilistic, the whole process is modeled by a finite homogeneous Markov chain, and the outcome is the corresponding stationary distribution. Based on our previous results for the asynchronous case—connecting the probability of a configuration in the stationary distribution to its number of zero-one borders—the article offers both numerical and theoretical insight into the long-term behavior of synchronous cellular automata. PMID:24999557

  20. Cellular therapy in tuberculosis.

    PubMed

    Parida, Shreemanta K; Madansein, Rajhmun; Singh, Nalini; Padayatchi, Nesri; Master, Iqbal; Naidu, Kantharuben; Zumla, Alimuddin; Maeurer, Markus

    2015-03-01

    Cellular therapy now offer promise of potential adjunct therapeutic options for treatment of drug-resistant tuberculosis (TB). We review here the role of Mesenchymal stromal cells, (MSCs), as well as other immune effector cells in the therapy of infectious diseases with a focus on TB. MSCs represent a population of tissue-resident non-hematopoietic adult progenitor cells which home into injured tissues increase the proliferative potential of broncho-alveolar stem cells and restore lung epithelium. MSCs have been shown to be immune-modulatory and anti-inflammatory mediated via cell-cell contacts as well as soluble factors. We discuss the functional profile of MSCs and their potential use for adjunct cellular therapy of multi-drug resistant TB, with the aim of limiting tissue damage, and to convert unproductive inflammatory responses into effective anti-pathogen directed immune responses. Adjunct cellular therapy could potentially offer salvage therapy options for patients with drug-resistant TB, increase clinically relevant anti-M.tuberculosis directed immune responses and possibly shorten the duration of anti-TB therapy. PMID:25809753