The College Access Debate: Class Considerations and College Preparation

ERIC Educational Resources Information Center

Hodgman, Matthew R.

2013-01-01

The college access debate in America remains an important one. Affirmative action policies and practices continue to occupy a significant sub-component of the overall college access discussion. Recent legal debates and policy changes pertaining to affirmative action have encouraged analysis surrounding the overall viability and fairness of these…

An Examination of the Benefits, Limitations, and Challenges of Conducting Randomized Experiments with Principals

ERIC Educational Resources Information Center

Camburn, Eric M.; Goldring, Ellen; Sebastian, James; May, Henry; Huff, Jason

2016-01-01

Purpose: The past decade has seen considerable debate about how to best evaluate the efficacy of educational improvement initiatives, and members of the educational leadership research community have entered the debate with great energy. Throughout this debate, the use of randomized experiments has been a particularly contentious subject. This…

Environmental impact assessment: Retrospect and prospect

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jay, Stephen; Jones, Carys; Slinn, Paul

2007-05-15

The widespread experience of environmental impact assessment (EIA) as an anticipatory environmental management tool has generated a considerable debate over the extent to which it is achieving its purposes. This has been measured in terms of EIA 'effectiveness', especially as discussion has moved away from issues of procedural implementation, to the more substantive goals of EIA and its place within broader decision-making contexts. Empirical studies have revealed the relatively weak degree of influence on planning decisions that is being exerted by EIA, which is increasingly being attributed to its rationalist beginnings. This article seeks to direct this debate towards themore » founding political purposes of EIA which, it is argued, provide a neglected, yet strong, basis for EIA reform. A number of illustrative suggestions are made as a result of this redirection, to enable EIA to adopt a more determinative role in decision making and to contribute to more sustainable patterns of development planning.« less

Essential Features of Responsible Governance of Agricultural Biotechnology

PubMed Central

Hartley, Sarah; Wickson, Fern

2016-01-01

Agricultural biotechnology continues to generate considerable controversy. We argue that to address this controversy, serious changes to governance are needed. The new wave of genomic tools and products (e.g., CRISPR, gene drives, RNAi, synthetic biology, and genetically modified [GM] insects and fish), provide a particularly useful opportunity to reflect on and revise agricultural biotechnology governance. In response, we present five essential features to advance more socially responsible forms of governance. In presenting these, we hope to stimulate further debate and action towards improved forms of governance, particularly as these new genomic tools and products continue to emerge. PMID:27144921

Essential Features of Responsible Governance of Agricultural Biotechnology.

PubMed

Hartley, Sarah; Gillund, Frøydis; van Hove, Lilian; Wickson, Fern

2016-05-01

Agricultural biotechnology continues to generate considerable controversy. We argue that to address this controversy, serious changes to governance are needed. The new wave of genomic tools and products (e.g., CRISPR, gene drives, RNAi, synthetic biology, and genetically modified [GM] insects and fish), provide a particularly useful opportunity to reflect on and revise agricultural biotechnology governance. In response, we present five essential features to advance more socially responsible forms of governance. In presenting these, we hope to stimulate further debate and action towards improved forms of governance, particularly as these new genomic tools and products continue to emerge.

Promoting renewable energy and energy efficiency in Africa: a framework to evaluate employment generation and cost effectiveness

NASA Astrophysics Data System (ADS)

Cantore, Nicola; Nussbaumer, Patrick; Wei, Max; Kammen, Daniel M.

2017-03-01

The ongoing debate over the cost-effectiveness of renewable energy (RE) and energy efficiency (EE) deployment often hinges on the current cost of incumbent fossil-fuel technologies versus the long-term benefit of clean energy alternatives. This debate is often focused on mature or ‘industrialized’ economies and externalities such as job creation. In many ways, however, the situation in developing economies is at least as or even more interesting due to the generally faster current rate of economic growth and of infrastructure deployment. On the one hand, RE and EE could help decarbonize economies in developing countries, but on the other hand, higher upfront costs of RE and EE could hamper short-term growth. The methodology developed in this paper confirms the existence of this trade-off for some scenarios, yet at the same time provides considerable evidence about the positive impact of EE and RE from a job creation and employment perspective. By extending and adopting a methodology for Africa designed to calculate employment from electricity generation in the U.S., this study finds that energy savings and the conversion of the electricity supply mix to renewable energy generates employment compared to a reference scenario. It also concludes that the costs per additional job created tend to decrease with increasing levels of both EE adoption and RE shares.

Digital Debates. WebWise Conference on Libraries and Museums in the Digital World Proceedings (10th, Capitol Hill, Washington, D.C, February 25-27, 2009)

ERIC Educational Resources Information Center

Zorich, Diane

2010-01-01

Debates typically invoke an image of individuals arguing over the merits of opposing viewpoints. However, the term has a softer, more deliberative sense that connotes reflection, discussion, and consideration. The 2009 WebWise conference, titled "Digital Debates," was conducted in this spirit, with panelists and attendees engaged in…

Nudges and coercion: conceptual, empirical, and normative considerations.

PubMed

Cratsley, Kelso

2015-01-01

Given that the concept of coercion remains a central concern for bioethics, Quigley's (Monash Bioethics Rev 32:141-158, 2014) recent article provides a helpful analysis of its frequent misapplication in debates over the use of 'nudges'. In this commentary I present a generally sympathetic response to Quigley's argument while also raising several issues that are important for the larger debates about nudges and coercion. I focus on several closely related topics, including the definition of coercion, the role of empirical research, and the normative concerns at the core of these disputes. I suggest that while a degree of precision is certainly required when deploying the relevant concepts, perhaps informed by empirical data, we need to continue to push these debates towards more pressing normative considerations.

Intimate Debate Technique: Medicinal Use of Marijuana

ERIC Educational Resources Information Center

Herreid, Clyde Freeman; DeRei, Kristie

2007-01-01

Classroom debates used to be familiar exercises to students schooled in past generations. In this article, the authors describe the technique called "intimate debate". To cooperative learning specialists, the technique is known as "structured debate" or "constructive debate". It is a powerful method for dealing with case topics that involve…

The levels of analysis revisited

PubMed Central

MacDougall-Shackleton, Scott A.

2011-01-01

The term levels of analysis has been used in several ways: to distinguish between ultimate and proximate levels, to categorize different kinds of research questions and to differentiate levels of reductionism. Because questions regarding ultimate function and proximate mechanisms are logically distinct, I suggest that distinguishing between these two levels is the best use of the term. Integrating across levels in research has potential risks, but many benefits. Consideration at one level can help generate novel hypotheses at the other, define categories of behaviour and set criteria that must be addressed. Taking an adaptationist stance thus strengthens research on proximate mechanisms. Similarly, it is critical for researchers studying adaptation and function to have detailed knowledge of proximate mechanisms that may constrain or modulate evolutionary processes. Despite the benefits of integrating across ultimate and proximate levels, failure to clearly identify levels of analysis, and whether or not hypotheses are exclusive alternatives, can create false debates. Such non-alternative hypotheses may occur between or within levels, and are not limited to integrative approaches. In this review, I survey different uses of the term levels of analysis and the benefits of integration, and highlight examples of false debate within and between levels. The best integrative biology reciprocally uses ultimate and proximate hypotheses to generate a more complete understanding of behaviour. PMID:21690126

Is Dance a Sport?: A Twenty-First-Century Debate

ERIC Educational Resources Information Center

Guarino, Lindsay

2015-01-01

This article discusses a new debate which has emerged for dancers. For many years dancers debated dance as art versus entertainment. This age-old debate still exists without a consensus, yet there is suddenly a new generation of dancers with a fresh debate. Legions of young performers are fervently proclaiming that their dance is actually a sport.…

The Benevolent Technocrat: Michael Dukakis' Strategy in the 1988 Presidential Debates.

ERIC Educational Resources Information Center

Herbeck, Dale A.

Michael Dukakis lost the presidential campaign debates of 1988 (or at least failed to capitalize as much as he might have) because he understood the debates to be genuine debates. Consequently, Dukakis acted as a debater generating an image of himself as a "benevolent technocrat," which was an error. It must be pointed out that the…

Current debates on end-of-life sedation: an international expert elicitation study.

PubMed

Papavasiliou, Evangelia Evie; Payne, Sheila; Brearley, Sarah

2014-08-01

End-of-life sedation, though increasingly prevalent and widespread internationally, remains one of the most highly debated medical practices in the context of palliative medicine. This qualitative study aims to elicit and record the perspectives of leading international palliative care experts on current debates. Twenty-one professionals from diverse backgrounds, sharing field-specific knowledge/expertise defined by significant scholarly contribution on end-of-life sedation, were recruited. Open-ended, semi-structured interviews, following a topic-oriented structure reflecting on current debates, were conducted. Results were analysed using thematic content analysis. Three main aspects of sedation were identified and discussed as potentially problematic: (a) continuous deep sedation as an extreme facet of end-of-life sedation, (b) psycho-existential suffering as an ambivalent indication for sedation and (c) withdrawal or withholding of artificial nutrition and hydration as potentially life-shortening. On these grounds, concerns were reported over end-of-life sedation being morally equivalent to euthanasia. Considerable emphasis was placed on intentions as the distinguishing factor between end-of-life acts, and protective safeguards were introduced to distance sedation from euthanasia. This study shows that, despite the safeguards introduced, certain aspects of sedation, including the intentions associated with the practice, are still under question, parallels being drawn between end-of-life sedation and euthanasia. This reaffirms the existence of a grey area surrounding the two practices, already evidenced in countries where euthanasia is legalized. More clarity over the issues that generate this grey area, with their causes being uncovered and eliminated, is imperative to resolve current debates and effectively inform research, policy and practice of end-of-life sedation.

The dream in contemporary psychiatry.

PubMed

Reiser, M F

2001-03-01

This article offers selective reviews of cogent sectors of research regarding the dream in contemporary psychiatry. First, the author discusses relatively recent research (1953-1999) on the neurobiology and clinical psychophysiology of dreaming sleep; second, he reviews experimental cognitive neuroscientific studies of perception, emotion, and memory and the putative interrelationships among them in generating dream imagery; and third, he interprets psychoanalytic studies (1900-1999) on related aspects of dreams and the dream process. Exploration for interrelationships among information from these three areas entails discussion of the mind/brain problem. These considerations illuminate some of the logical and interpretive dilemmas that enter into debates about Freud's theory of the dream. The author proposes a preliminary psychobiologic concept of the dream process and discusses, in light of the foregoing considerations, the importance of collaborative research for developing a realistic perspective concerning the proper place of the dream in contemporary psychiatry.

Genetic Engineering--A Lesson on Bioethics for the Classroom.

ERIC Educational Resources Information Center

Armstrong, Kerri; Weber, Kurt

1991-01-01

A unit designed to cover the topic of genetic engineering and its ethical considerations is presented. Students are expected to learn the material while using a debate format. A list of objectives for the unit, the debate format, and the results from an opinion questionnaire are described. (KR)

The Current and Future Role of Business Schools

ERIC Educational Resources Information Center

Rayment, John; Smith, Jonathan

2013-01-01

Purpose: Considerable debate since the global financial crisis has been evident concerning the role of business schools. This article aims to outline the authors' research on their role. Design/methodology/approach: The paper begins with an overview of the significant literature highlighting the current debates impacting on business schools and…

Supporting Evidence-Based Policy on Biodiversity and Ecosystem Services: Recommendations for Effective Policy Briefs

ERIC Educational Resources Information Center

Balian, Estelle V.; Drius, Liza; Eggermont, Hilde; Livoreil, Barbara; Vandewalle, Marie; Vandewoestjine, Sofie; Wittmer, Heidi; Young, Juliette

2016-01-01

Knowledge brokerage on biodiversity and ecosystem services can apply communication tools such as policy briefs to facilitate the dialogue between scientists and policymakers. There is currently considerable debate on how to go beyond the linear communication model, outdated in theoretical debate but still often implicitly leading interaction with…

Challenges for an Interdisciplinary Consideration of Cognitive Training

ERIC Educational Resources Information Center

Birney, Damian Patrick

2015-01-01

Whether fluid cognitive functions are malleable has been a topic of ongoing debate for at least the past 100 years. Ever-evolving technology has led to new and diverse fields of investigation entering this debate. There are significant advantages to be gained by integrating different scientific paradigms, but there are also significant challenges.…

Active water transport in unicellular algae: where, why, and how.

PubMed

Raven, John A; Doblin, Martina A

2014-12-01

The occurrence of active water transport (net transport against a free energy gradient) in photosynthetic organisms has been debated for several decades. Here, active water transport is considered in terms of its roles, where it is found, and the mechanisms by which it could occur. First there is a brief consideration of the possibility of active water transport into plant xylem in the generation of root pressure and the refilling of embolized xylem elements, and from an unsaturated atmosphere into terrestrial organisms living in habitats with limited availability of liquid water. There is then a more detailed consideration of volume and osmotic regulation in wall-less freshwater unicells, and the possibility of generation of buoyancy in marine phytoplankton such as large-celled diatoms. Calculations show that active water transport is a plausible mechanism to assist cells in upwards vertical movements, requires less energy than synthesis of low-density organic solutes, and potentially on a par with excluding certain ions from the vacuole. © The Author 2014. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Restyling the Humanities Curriculum of Higher Education for Posthuman Times

ERIC Educational Resources Information Center

Siddiqui, Jamila R.

2016-01-01

The future viability of the humanities in higher education has been broadly debated. Yet, most of these debates are missing an important consideration. The humanities' object of study is the human, an object that some would argue has been replaced in our onto-epistemological systems by the posthuman. In her 2013 book, "The Posthuman,"…

75 FR 66725 - National Fire Protection Association (NFPA) Proposes To Revise Codes and Standards

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-29

... Technical Committee by a formal written ballot. If the ROP does not receive approval by a two-thirds vote.... Following the completion of the Proposal and Comment periods, there is a further opportunity for debate and... the debate and consideration of motions to amend the Report. Before making an allowable motion at an...

Risking a Debate--Redefining Risk and Risk Management: A New Zealand Case Study.

ERIC Educational Resources Information Center

Zink, Robyn; Leberman, Sarah

2001-01-01

Interviews with 12 New Zealand outdoor instructors found that they viewed risk as an opportunity to gain something of value, as opposed to losing something of value. Repositioning risk in this manner could allow the debate around adventure education to move away from being dominated by risk management, allowing consideration of adventure…

Popular misconceptions: agricultural biotechnology.

PubMed

McHughen, Alan; Wager, Robert

2010-12-31

Agricultural biotechnology, especially genetic engineering or genetic modification (GM), is a topic of considerable controversy worldwide. The public debate is fraught with polarized views and opinions, some are held with religious zeal. Unfortunately, it is also marked with much ignorance and misinformation. Here we explore some popular misconceptions encountered in the public debate. Copyright © 2010 Elsevier B.V. All rights reserved.

Academic Disciplines and Debates: An Essay on Criminal Justice and Criminology as Professions in Higher Education.

ERIC Educational Resources Information Center

Morn, Frank T.

Current developments concerning criminology and criminal justice education are viewed historically and placed within a broader perspective of academic professionalization, and a few of the debates going on within and between the two fields are considered. Some early sociologists made considerable claim to studies of crime, and criminology and…

The Role of Universities in Supporting and Delivering Enterprise Education

ERIC Educational Resources Information Center

Edwards, Louise-Jayne; Muir, Elizabeth J.

2007-01-01

While the academic debate has moved beyond the question of whether or not entrepreneurship can be taught and whether or not there is a need or demand for it, there is still considerable debate as to the most appropriate methods of delivering entrepreneurship education. This paper provides an overview of teaching strategies, pedagogies and methods…

Tracheal bioengineering: the next steps. Proceeds of an International Society of Cell Therapy Pulmonary Cellular Therapy Signature Series Workshop, Paris, France, April 22, 2014.

PubMed

Weiss, Daniel J; Elliott, Martin; Jang, Queenie; Poole, Brian; Birchall, Martin

2014-12-01

There has been significant and exciting recent progress in the development of bioengineering approaches for generating tracheal tissue that can be used for congenital and acquired tracheal diseases. This includes a growing clinical experience in both pediatric and adult patients with life-threatening tracheal diseases. However, not all of these attempts have been successful, and there is ongoing discussion and debate about the optimal approaches to be used. These include considerations of optimal materials, particularly use of synthetic versus biologic scaffolds, appropriate cellularization of the scaffolds, optimal surgical approaches and optimal measure of both clinical and biologic outcomes. To address these issues, the International Society of Cell Therapy convened a first-ever meeting of the leading clinicians and tracheal biologists, along with experts in regulatory and ethical affairs, to discuss and debate the issues. A series of recommendations are presented for how to best move the field ahead. Copyright © 2014 International Society for Cellular Therapy. Published by Elsevier Inc. All rights reserved.

[Critical reflections concerning euthanasia for persons with dementia].

PubMed

De Lepeleire, J; Beyen, A; Burin, M; Fabri, R; Ghijsebrechts, G; Lisaerde, J; Temmerman, B; Van den Eynden, B; Van den Noortgate, N

2010-01-01

In the public debate on the extension of euthanasia for people with dementia, in addition to ethical considerations and arguments, other issues have to be kept in mind. The diagnosis of dementia is difficult and the clinical picture is very fluctuating. The assessment and especially the operationalization of legal capacity and the use of advance directives are complex problems. The discussion should be conducted against the backdrop of a cultural framework in which the interpretation and development of palliative care is crucial. The development of a framework like advance care planning creates opportunities. The question remains whether the legal issues can be clarified and whether a legal approach generates solutions for the problems described.

Commercialization, patents and moral assessment of biotechnology products.

PubMed

Hoedemaekers, R

2001-06-01

The biotechnology patent debates have revealed deep moral concerns about basic genetics research, R&D and specific biotechnological products, concerns that are seldom taken into consideration in Technology Assessment. In this paper important moral concerns are examined which appear at the various stages of development of a specific genetic product: a predictive genetic test. The purpose is to illustrate the need for a more contextual approach in technology assessment, which integrates the various forms of interaction between bio-technology and society or societal segments. Such an approach will generate greater insight in the moral issues at all stages of a product's life-cycle and this will facilitate decision-making on the 'morality' of a specific biotechnological product.

Networked Learning: Design Considerations for Online Instructors

ERIC Educational Resources Information Center

Czerkawski, Betul C.

2016-01-01

The considerable increase in web-based knowledge networks in the past two decades is strongly influencing learning environments. Learning entails information retrieval, use, communication, and production, and is strongly enriched by socially mediated discussions, debates, and collaborative activities. It is becoming critical for educators to…

Russian Dreams and Prussian Ghosts: Immanuel Kant Baltic Federal University and Debates over Historical Memory and Identity in Kaliningrad

ERIC Educational Resources Information Center

Clarkson, Alexander

2017-01-01

This article examines how the Immanuel Kant Baltic Federal University and the Kaliningrad State Technical University have come to exert considerable influence over debates surrounding historical memory and identity in the Kaliningrad region. Under the direct control of the Russian Federation, the Baltic exclave of Kaliningrad is surrounded by…

The Creative Problem Solving Skills of Arts and Science Students--The Two Cultures Debate Revisited

ERIC Educational Resources Information Center

Williamson, Peter K.

2011-01-01

Research, carried out mainly in the period between the 1960s and 1980s, reported significant differences in the thinking styles of science and arts students. At this time university and school teaching was highly specialised and concern was expressed in the ongoing "two cultures" debate (Snow, 1959).Considerable changes have taken place in the…

NORMAL HUMAN VARIATION: REFOCUSSING THE ENHANCEMENT DEBATE

PubMed Central

Kahane, Guy; Savulescu, Julian

2015-01-01

This article draws attention to several common mistakes in thinking about biomedical enhancement, mistakes that are made even by some supporters of enhancement. We illustrate these mistakes by examining objections that John Harris has recently raised against the use of pharmacological interventions to directly modulate moral decision-making. We then apply these lessons to other influential figures in the debate about enhancement. One upshot of our argument is that many considerations presented as powerful objections to enhancement are really strong considerations in favour of biomedical enhancement, just in a different direction. Another upshot is that it is unfortunate that much of the current debate focuses on interventions that will radically transform normal human capacities. Such interventions are unlikely to be available in the near future, and may not even be feasible. But our argument shows that the enhancement project can still have a radical impact on human life even if biomedical enhancement operated entirely within the normal human range. PMID:23906367

Debating DSM-5: diagnosis and the sociology of critique

PubMed Central

Pickersgill, Martyn D

2014-01-01

The development of the fifth edition of the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders—the DSM-5—has reenergised and driven further forward critical discourse about the place and role of diagnosis in mental health. The DSM-5 has attracted considerable criticism, not least about its role in processes of medicalisation. This paper suggests the need for a sociology of psychiatric critique. Sociological analysis can help map fields of contention, and cast fresh light on the assumptions and nuances of debate around the DSM-5; it underscores the importance of diagnosis to the governance of social and clinical life, as well as the wider discourses critical commentaries connect with and are activated by. More normatively, a sociology of critique can indicate which interests and values are structuring the dialogues being articulated, and just how diverse clinical opinion regarding the DSM can actually be. This has implications for the considerations of health services and policy decision-makers who might look to such debates for guidance. PMID:24327375

[External and internal financing in health care].

PubMed

Henke, Klaus-Dirk

2007-05-15

The objective of this contribution is to characterize the functional and institutional features of the German health-care system. This takes place after a short introduction and examination of the ongoing debate on health care in Germany. External funding describes the form of revenue generation. Regarding external funding of the German health care system, one of the favored alternatives in the current debate is the possibility of introducing per capita payments. After a short introduction to the capitation option, focus is on the so-called health fund that is currently debated on and being made ready for implementation in Germany, actually a mixed system of capitation and contributions based on income. On the other hand, internal funding is the method of how different health-care services are purchased or reimbursed. This becomes a rather hot topic in light of new trends for integrated and networked care to patients and different types of budgeting. Another dominating question in the German health-care system is the liberalization of the contractual law, with its "joint and uniform" regulations that have to be loosened for competition gains. After a discussion of the consequences of diagnosis-related groups (DRGs) in Germany, the article is concluded by a note on the political rationality of the current health-care reform for increased competition within the Statutory Health Insurance and its players as exemplified by the health fund. To sum up, it has to be said that the complexity and specific features of how the German system is financed seem to require ongoing reform considerations even after realization of the currently debated health-care reform law which, unfortunately, is dominated by political rationalities rather than objective thoughts.

From Theory to Research: Contextual Predictors of "Estar + Adjective" and the Study of the SLA of Spanish Copula Choice--A Response to Woolsey

ERIC Educational Resources Information Center

Lafford, Barbara A.

2008-01-01

The use of social vs. cognitive approaches to the study of second language acquisition (SLA) has engendered considerable debate in the field. For instance, the recent "Modern Language Journal" Focus Issue (Lafford, 2007a) reviewed the ongoing debate between scholars espousing socially- and cognitively-grounded approaches to SLA research and…

Study design elements for rigorous quasi-experimental comparative effectiveness research.

PubMed

Maciejewski, Matthew L; Curtis, Lesley H; Dowd, Bryan

2013-03-01

Quasi-experiments are likely to be the workhorse study design used to generate evidence about the comparative effectiveness of alternative treatments, because of their feasibility, timeliness, affordability and external validity compared with randomized trials. In this review, we outline potential sources of discordance in results between quasi-experiments and experiments, review study design choices that can improve the internal validity of quasi-experiments, and outline innovative data linkage strategies that may be particularly useful in quasi-experimental comparative effectiveness research. There is an urgent need to resolve the debate about the evidentiary value of quasi-experiments since equal consideration of rigorous quasi-experiments will broaden the base of evidence that can be brought to bear in clinical decision-making and governmental policy-making.

Do gaming disorder and hazardous gaming belong in the ICD-11? Considerations regarding the death of a hospitalized patient that was reported to have occurred while a care provider was gaming.

PubMed

Potenza, Marc N

2018-05-23

There has been much debate regarding the extent to which different types and patterns of gaming may be considered harmful from individual and public health perspectives. A recent event in which a hospitalized patient was reported to have died while a care provider was gaming is worth considering as an example as to how gaming may distract individuals from work-related tasks or other activities, with potential negative consequences. As the 11th edition of the International Classification of Diseases is being developed, events like these are important to remember when considering entities like, and generating criteria for, disordered or hazardous gaming.

Post-acute care and vertical integration after the Patient Protection and Affordable Care Act.

PubMed

Shay, Patrick D; Mick, Stephen S

2013-01-01

The anticipated changes resulting from the passage of the Patient Protection and Affordable Care Act-including the proposed adoption of bundled payment systems and the promotion of accountable care organizations-have generated considerable controversy as U.S. healthcare industry observers debate whether such changes will motivate vertical integration activity. Using examples of accountable care organizations and bundled payment systems in the American post-acute healthcare sector, this article applies economic and sociological perspectives from organization theory to predict that as acute care organizations vary in the degree to which they experience environmental uncertainty, asset specificity, and network embeddedness, their motivation to integrate post-acute care services will also vary, resulting in a spectrum of integrative behavior.

The evolution of policy issues in stem cell research: an international survey.

PubMed

Caulfield, Timothy; Rachul, Christen; Zarzeczny, Amy

2012-12-01

Stem cell research remains a tremendously promising yet controversial field of study. It continues to attract considerable public interest and generate discussion and debate. However, while the high profile of this field has endured, the tone and nature of the discourse that drives this profile appears to be changing. In order to get a better sense of how these potential shifts are perceived by individuals directly embedded in the field, we conducted an international internet survey of members of the stem cell research community. Our participants included individuals publishing on both scientific and ethical, legal and social issues topics. We explored the degree to which participants perceived that key policy issues were becoming more or less contentious over time. We queried views regarding the effect of regulatory frameworks on emerging stem cell research technologies and the extent to which participants experience pressure related to clinical translation. We also explored participants' relationships with industry, experience with patents and perceptions regarding the emphasis placed on the potential economic benefits of stem cell research. Our results suggest that while traditional debates such as those surrounding the moral status of the embryo remain, other issues more closely associated with clinical translation and commercialization are perceived as becoming increasingly contentious. This survey provides useful insight into the perspectives of a sample of active researchers working in countries around the world as well as an opportunity to reflect on the likely direction of future stem cell policy debates.

Opportunities and challenges for the integration of massively parallel genomic sequencing into clinical practice: lessons from the ClinSeq project.

PubMed

Biesecker, Leslie G

2012-04-01

The debate surrounding the return of results from high-throughput genomic interrogation encompasses many important issues including ethics, law, economics, and social policy. As well, the debate is also informed by the molecular, genetic, and clinical foundations of the emerging field of clinical genomics, which is based on this new technology. This article outlines the main biomedical considerations of sequencing technologies and demonstrates some of the early clinical experiences with the technology to enable the debate to stay focused on real-world practicalities. These experiences are based on early data from the ClinSeq project, which is a project to pilot the use of massively parallel sequencing in a clinical research context with a major aim to develop modes of returning results to individual subjects. The study has enrolled >900 subjects and generated exome sequence data on 572 subjects. These data are beginning to be interpreted and returned to the subjects, which provides examples of the potential usefulness and pitfalls of clinical genomics. There are numerous genetic results that can be readily derived from a genome including rare, high-penetrance traits, and carrier states. However, much work needs to be done to develop the tools and resources for genomic interpretation. The main lesson learned is that a genome sequence may be better considered as a health-care resource, rather than a test, one that can be interpreted and used over the lifetime of the patient.

Wound Microbiology and Associated Approaches to Wound Management

PubMed Central

Bowler, P. G.; Duerden, B. I.; Armstrong, D. G.

2001-01-01

The majority of dermal wounds are colonized with aerobic and anaerobic microorganisms that originate predominantly from mucosal surfaces such as those of the oral cavity and gut. The role and significance of microorganisms in wound healing has been debated for many years. While some experts consider the microbial density to be critical in predicting wound healing and infection, others consider the types of microorganisms to be of greater importance. However, these and other factors such as microbial synergy, the host immune response, and the quality of tissue must be considered collectively in assessing the probability of infection. Debate also exists regarding the value of wound sampling, the types of wounds that should be sampled, and the sampling technique required to generate the most meaningful data. In the laboratory, consideration must be given to the relevance of culturing polymicrobial specimens, the value in identifying one or more microorganisms, and the microorganisms that should be assayed for antibiotic susceptibility. Although appropriate systemic antibiotics are essential for the treatment of deteriorating, clinically infected wounds, debate exists regarding the relevance and use of antibiotics (systemic or topical) and antiseptics (topical) in the treatment of nonhealing wounds that have no clinical signs of infection. In providing a detailed analysis of wound microbiology, together with current opinion and controversies regarding wound assessment and treatment, this review has attempted to capture and address microbiological aspects that are critical to the successful management of microorganisms in wounds. PMID:11292638

Inactivation of Mycobacterium avium subsp. paratuberculosis during cooking of hamburger patties.

PubMed

Hammer, Philipp; Walte, Hans-Georg C; Matzen, Sönke; Hensel, Jann; Kiesner, Christian

2013-07-01

The role of Mycobacterium avium subsp. paratuberculosis (MAP) in Crohn's disease in humans has been debated for many years. Milk and milk products have been suggested as possible vectors for transmission since the beginning of this debate, whereas recent publications show that slaughtered cattle and their carcasses, meat, and organs can also serve as reservoirs for MAP transmission. The objective of this study was to generate heat-inactivation data for MAP during the cooking of hamburger patties. Hamburger patties of lean ground beef weighing 70 and 50 g were cooked for 6, 5, 4, 3, and 2 min, which were sterilized by irradiation and spiked with three different MAP strains at levels between 10² and 10⁶ CFU/ml. Single-sided cooking with one flip was applied, and the temperatures within the patties were recorded by seven thermocouples. Counting of the surviving bacteria was performed by direct plating onto Herrold's egg yolk medium and a three-vial most-probable-number method by using modified Dubos medium. There was considerable variability in temperature throughout the patties during frying. In addition, the log reduction in MAP numbers showed strong variations. In patties weighing 70 g, considerable bacterial reduction of 4 log or larger could only be achieved after 6 min of cooking. For all other cooking times, the bacterial reduction was less than 2 log. Patties weighing 50 g showed a 5-log or larger reduction after cooking times of 5 and 6 min. To determine the inactivation kinetics, a log-linear regression model was used, showing a constant decrease of MAP numbers over cooking time.

Development of a consensus approach for return of pathology incidental findings in the Genotype-Tissue Expression (GTEx) project.

PubMed

Lockhart, Nicole C; Weil, Carol J; Carithers, Latarsha J; Koester, Susan E; Little, A Roger; Volpi, Simona; Moore, Helen M; Berkman, Benjamin E

2018-06-14

The active debate about the return of incidental or secondary findings in research has primarily focused on return to research participants, or in some cases, family members. Particular attention has been paid to return of genomic findings. Yet, research may generate other types of findings that warrant consideration for return, including findings related to the pathology of donated biospecimens. In the case of deceased biospecimen donors who are also organ and/or tissue transplant donors, pathology incidental findings may be relevant not to family members, but to potential organ or tissue transplant recipients. This paper will describe the ethical implications of pathology incidental findings in the Genotype-Tissue Expression (GTEx) project, the process for developing a consensus approach as to if/when such findings should be returned, possible implications for other research projects collecting postmortem tissues and how the scenario encountered in GTEx fits into the larger return of results/incidental findings debate. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Competitive Debate as Competency-Based Learning: Civic Engagement and Next-Generation Assessment in the Era of the Common Core Learning Standards

ERIC Educational Resources Information Center

McIntosh, Jonathan; Milam, Myra

2016-01-01

As the adoption and execution of the Common Core State Standards (CCSS) have steadily increased, the debate community is presented with an opportunity to be more forward thinking and sustainable through the translation to curriculum planning and next-generation assessment as a movement towards Performance-Based Assessments. This paper focuses on…

Ship's doctors qualifications required for cruise ships: Recruiter's comments on the German-Norwegian debate.

PubMed

Ottomann, Christian

2015-01-01

This contribution is intended to fertilise the current discussion of ship's doctors qualifications required for cruise ships. Therefore 10 points are added to the debate containing different considerations focussing on the recommendations of the German Society of Maritime Medicine, the American College of Emergency Physicians (ACEP's) Health Care Guidelines for Cruise Ship Medical Facilities and the different skills a ship's doctor should have from the perspective of the recruiter.

How Can Educational Planning Be Rational? A Consideration of the Process of Educational Planning in Terms of the Problem of Rationality in the Social World.

ERIC Educational Resources Information Center

McGrath, Helen Marie

This paper takes up an issue that is currently being debated in the educational planning literature--the adequacy of the central assumption of rationality in the formulation of public policy planning. It identifies the nature of the rationality that is being called into question and rephrases the debate in terms of the tenability of an assumption…

When Sexual and Religious Orientation Collide: Considerations in Working with Conflicted Same-Sex Attracted Male Clients

ERIC Educational Resources Information Center

Haldeman, Douglas C.

2004-01-01

The debate among scholars and gay activists and religious/political activists about the appropriateness and efficacy of conversion therapy has left out a number of individuals for whom neither gay-affirmative nor conversion therapy may be indicated. The present discussion, through the use of case material, offers considerations for the…

Making Sense of the GATS Debate: Semiotic Analysis of the Conflicting Ideas on the Education/Free-Trade Relationship

ERIC Educational Resources Information Center

Verger, Antoni

2011-01-01

The General Agreement on Trade in Services (GATS) of the World Trade Organization has generated an intense and passionate debate about the relationship between free-trade and education and, specifically, about the effects of trade liberalization in national education systems. This article explores in detail this debate from a critical discourse…

Using Small Group Debates to Actively Engage Students in an Introductory Microbiology Course†

PubMed Central

Shaw, Joyce A.

2012-01-01

Debates stimulate critical thinking and can be a highly effective way to actively engage students in the classroom. This paper describes a small group debate format in which groups of four to six students debated preassigned topics in microbiology in front of the rest of the class. Rapid advancements in science, especially in microbiology, provide the scaffolding for students to locate and share evidence-based information from a plethora of complex and often conflicting sources. Student-generated debate presentations can be a welcome respite from the lecture format. Debates were scheduled throughout the course to coincide with topics being covered. Questionnaires distributed immediately after each debate revealed that the debates were well received by students and were effective in changing student attitudes and misconceptions. Debate preparation provided students the opportunity to gain proficiency in accessing information from electronic databases, to use resources from professional organizations, and to synthesize and analyze information. In addition, the debate process gave students experience in developing oral communication skills. PMID:23653803

UK parliamentary debate analysis: bombing ISIL in Syria.

PubMed

Rashed, Haifa

2016-01-01

This paper examines the arguments presented for and against the UK government's motion for the UK to intervene militarily in Syria in the House of Commons debate on ISIL in Syria that took place on 2 December 2015. It considers what the most common arguments were in favour of and in opposition to the motion as well as which arguments were given the most emphasis, in order to understand the prime justifications given that led to the decision to approve the motion. It suggests that due to the shadow of the 2003 Iraq war, politicians in the debate placed a considerable emphasis on the legal justification for military intervention. It argues that the focus on the national security of the UK and its allies in this particular debate seems to contrast with previous military interventions where humanitarian motives were more widely stated. This paper calls for further comparative research of parliamentary debates in order to track such changes in the rhetoric used by UK politicians to defend their support for military intervention.

A Tricky Trait: Applying the Fruits of the "Function Debate" in the Philosophy of Biology to the "Venom Debate" in the Science of Toxinology.

PubMed

Jackson, Timothy N W; Fry, Bryan G

2016-09-07

The "function debate" in the philosophy of biology and the "venom debate" in the science of toxinology are conceptually related. Venom systems are complex multifunctional traits that have evolved independently numerous times throughout the animal kingdom. No single concept of function, amongst those popularly defended, appears adequate to describe these systems in all their evolutionary contexts and extant variations. As such, a pluralistic view of function, previously defended by some philosophers of biology, is most appropriate. Venom systems, like many other functional traits, exist in nature as points on a continuum and the boundaries between "venomous" and "non-venomous" species may not always be clearly defined. This paper includes a brief overview of the concept of function, followed by in-depth discussion of its application to venom systems. A sound understanding of function may aid in moving the venom debate forward. Similarly, consideration of a complex functional trait such as venom may be of interest to philosophers of biology.

Shostakovich versus the Central Committee: the power of music.

PubMed

White, Richard H R

2008-08-01

The centenary of Shostakovich's birth, celebrated in 2006, generated considerable interest in his life and music. During the Cold War his music was rarely played in the West, and it was not until after his death in 1975 that it re-emerged. The publication of his memoirs in the UK, in 1979, gave new insights into his life in Soviet Russia. Music, like art and literature, has the power to shock and can reflect anger and frustration at contemporary social issues. Much debate has focused on whether Shostakovich was a victim or mouthpiece of Communism. In order to fully appreciate his music, it is essential to understand his personal and professional life under Josef Stalin--in particular his public humiliation by the Central Committee, and by professional musicians who were Communist Party members.

Withdrawing may be preferable to withholding

PubMed Central

Vincent, Jean-Louis

2005-01-01

The majority of deaths on the intensive care unit now occur following a decision to limit life-sustaining therapy, and end-of-life decision making is an accepted and important part of modern intensive care medical practice. Such decisions can essentially take one of two forms: withdrawing – the removal of a therapy that has been started in an attempt to sustain life but is not, or is no longer, effective – and withholding – the decision not to make further therapeutic interventions. Despite wide agreement by Western ethicists that there is no ethical difference between these two approaches, these issues continue to generate considerable debate. In this article, I will provide arguments why, although the two actions are indeed ethically equivalent, withdrawing life-sustaining therapy may in fact be preferable to withholding. PMID:15987405

Promoting research participation: why not advertise altruism?

PubMed

Williams, Brian; Entwistle, Vikki; Haddow, Gill; Wells, Mary

2008-04-01

Participation rates have a major impact on the quality, cost and timeliness of health research. There is growing evidence that participation rates may be falling and that new research governance structures and procedures may be increasing the likelihood of recruitment bias. It may be possible to encourage public reflection about research participation and enhance recruitment by providing information about the potential benefits of research to others as well as to research participants and by stimulating debate and influencing social expectations about involvement. Publicly funded and charitable bodies use various forms of advertising to encourage altruistic behaviour and generate social expectations about donating money, blood and organs for the benefit of others. Consideration should be given to the use of similar persuasive communications to promote wider participation in health research generally.

What is knowledge and when should it be implemented?

PubMed

O'Grady, Laura

2012-10-01

A primary purpose of research is to generate new knowledge. Scientific advances have progressively identified optimal ways to achieve this purpose. Included in this evolution are the notions of evidence-based medicine, decision aids, shared decision making, measurement and evaluation as well as implementation. The importance of including qualitative and quantitative methods in our research is now understood. We have debated the meaning of evidence and how to implement it. However, we have yet to consider how to include in our study findings other types of information such as tacit and experiential knowledge. This key consideration needs to take place before we translate new findings or 'knowledge' into clinical practice. This article critiques assumptions regarding the nature of knowledge and suggests a framework for implementing research findings into practice. © 2012 Blackwell Publishing Ltd.

Debate continues on northwest's merits

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stremel, K.

1984-07-01

Estimates of northwest Montana's petroleum reserves range from barren Precambrian rock to reserves exceeding those of Alaska's Prudhoe Bay. Geological debates concerning the merits of the vast areas continues. Seismic data and geological studies indicate that the area holds considerable promise. Several large structures have been identified, and oil and gas seeps have been reported. The area's true potential, however, will be revealed only by drilling, which is both risky and expensive. Several wildcat drilling operations are underway but the area's hydrocarbon potential may not be released for several years.

Social Welfare Policy and Inequalities in Health. Preconceived Truths in Scientific Research.

PubMed

Regidor, Enrique

2016-08-02

At the end of the first decade of the present century debates arose in social epidemiology. These debates set those who defend the existence of a relation between the political and/or welfare stage regime and the magnitude of socioeconomic inequalities in health against those who maintain the facts do not support such a relation. These debates are similar to other debates in epidemiology in the 1990s related with theories of how diseases are produced and the factors that determine their distribution in the population. Whereas some authors find it impossible to separate ethical and political aspects and professional values from scientific arguments, others consider that epidemiologists and other scientists should make an effort to distinguish between scientific and unscientific considerations. In this paper the author reflects about the harmony that keep science, politics and ethics in the scientific practice on health inequalities, although the empirical evidence is contrary to that harmonious effect.

Framing the policy debate over spirits excise tax in Poland.

PubMed

Zatonski, Mateusz; Hawkins, Benjamin; McKee, Martin

2018-06-01

Industry lobbying remains an obstacle to effective health-oriented alcohol policy. In 2013, an increase in excise tax on spirits was announced by the Polish government. This article presents a qualitative analysis of the public debate that ensued on the potential economic, health and social effects of the policy. It focuses on how competing groups, including industry actors, framed their position and sought to dominate the debate. Online archives of five Polish national newspapers, two spirits trade associations, and parliamentary and ministerial archives were searched. A thematic content analysis of the identified sources was conducted. The overall findings were compared with existing research on the framing of the Minimum Unit Pricing (MUP) debate in the UK. A total of 155 sources were analysed. Two main frames were identified: health, and economic. The spirits industry successfully promoted the economic frame in their own publications and in the media. The debate was dominated by arguments about potential growth of the grey market and losses in tax revenue that might result from the excise tax increase. The framing of the debate in Poland differed from the framing of the MUP debate in the United Kingdom. The Polish public health community was unsuccessful in making health considerations a significant element of the alcohol policy debate. The strategies pursued by UK health advocates offer lessons for how to make a more substantial impact on media coverage and promote health-oriented legislation.

Debating DSM-5: diagnosis and the sociology of critique.

PubMed

Pickersgill, Martyn D

2014-08-01

The development of the fifth edition of the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders-the DSM-5-has reenergised and driven further forward critical discourse about the place and role of diagnosis in mental health. The DSM-5 has attracted considerable criticism, not least about its role in processes of medicalisation. This paper suggests the need for a sociology of psychiatric critique. Sociological analysis can help map fields of contention, and cast fresh light on the assumptions and nuances of debate around the DSM-5; it underscores the importance of diagnosis to the governance of social and clinical life, as well as the wider discourses critical commentaries connect with and are activated by. More normatively, a sociology of critique can indicate which interests and values are structuring the dialogues being articulated, and just how diverse clinical opinion regarding the DSM can actually be. This has implications for the considerations of health services and policy decision-makers who might look to such debates for guidance. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

A Framework for Analysis of Research Risks and Benefits to Participants in Standard of Care Pragmatic Clinical Trials

PubMed Central

Chen, Stephanie C; Kim, Scott Y H

2016-01-01

Background/Aims Standard of care pragmatic clinical trials (SCPCTs) that compare treatments already in use could improve care and reduce cost but there is considerable debate about the research risks of SCPCTs and how to apply informed consent regulations to such trials. We sought to develop a framework integrating the insights from opposing sides of the debate. Methods We developed a formal risk-benefit analysis framework for SCPCTs and then applied it to key provisions of the U.S. federal regulations. Results Our formal framework for SCPCT risk-benefit analysis takes into account three key considerations: the ex ante estimates of risks and benefits of the treatments to be compared in a SCPCT, the allocation ratios of treatments inside and outside a SCPCT, and the significance of some participants receiving a different treatment inside a SCPCT than outside the trial. The framework provides practical guidance on how the research ethics regulations on informed consent should be applied to SCPCTs. Conclusions Our proposed formal model makes explicit the relationship between the concepts used by opposing sides of the debate about the research risks of SCPCTs and can be used to clarify the implications for informed consent. PMID:27365010

Moving research beyond the spanking debate.

PubMed

MacMillan, Harriet L; Mikton, Christopher R

2017-09-01

Despite numerous studies identifying a broad range of harms associated with the use of spanking and other types of physical punishment, debate continues about its use as a form of discipline. In this commentary, we recommend four strategies to move the field forward and beyond the spanking debate including: 1) use of methodological approaches that allow for stronger causal inference; 2) consideration of human rights issues; 3) a focus on understanding the causes of spanking and reasons for its decline in certain countries; and 4) more emphasis on evidence-based approaches to changing social norms to reject spanking as a form of discipline. Physical punishment needs to be recognized as an important public health problem. Copyright © 2017 Elsevier Ltd. All rights reserved.

Contribution of different generations of the brown shrimp Crangon crangon (L.) in the Dutch Wadden Sea to commercial fisheries: A dynamic energy budget approach

NASA Astrophysics Data System (ADS)

Campos, Joana; Van der Veer, Henk W.; Freitas, Vânia; Kooijman, Sebastiaan A. L. M.

2009-08-01

In this paper a contribution is made to the ongoing debate on which brown shrimp generation mostly sustains the autumn peak in coastal North Sea commercial fisheries: the generation born in summer, or the winter one. Since the two perspectives are based on different considerations on the growth timeframe from settlement till commercial size, the Dynamic Energy Budget (DEB) theory was applied to predict maximum possible growth under natural conditions. First, the parameters of the standard DEB model for Crangon crangon L. were estimated using available data sets. These were insufficient to allow a direct estimation, requiring a special protocol to achieve consistency between parameters. Next, the DEB model was validated by comparing simulations with published experimental data on shrimp growth in relation to water temperatures. Finally, the DEB model was applied to simulate growth under optimal food conditions using the prevailing water temperature conditions in the Wadden Sea. Results show clear differences between males and females whereby the fastest growth rates were observed in females. DEB model simulations of maximum growth in the Wadden Sea suggest that it is not the summer brood from the current year as Boddeke claimed, nor the previous winter generation as Kuipers and Dapper suggested, but more likely the summer generation from the previous year which contributes to the bulk of the fisheries recruits in autumn.

Nature of the Band Gap and Origin of the Electro-/Photo-Activity of Co3O4

DOE Office of Scientific and Technical Information (OSTI.GOV)

Qiao, L.; Xiao, Haiyan Y.; Meyer, H. M.

2013-08-21

Co3O4 exhibits intriguing physical, chemical and catalytic properties and has demonstrated great potential for next-generation renewable energy applications. These interesting properties and promising applications are underpinned by its electronic structure and optical properties, which are unfortunately poorly understood and the subject of considerable debate over many years. Here, we unveil a consistent electronic structural description of Co3O4 by synergetic infrared optical and in situ photoemission spectroscopy as well as standard density functional theory calculations. In contrast to previous assumptions, we demonstrate a much smaller fundamental band gap, which is directly related to its efficient electro-/photoactivity. The present results may helpmore » to advance the fundamental understanding and provide guidance for the use of oxidematerials in photocatalysis and solar applications.« less

Understanding men's health and illness: a gender-relations approach to policy, research, and practice.

PubMed

Schofield, T; Connell, R W; Walker, L; Wood, J F; Butland, D L

2000-05-01

Men's health has emerged as an important public concern that may require new kinds of healthcare interventions and increased resources. Considerable uncertainty and confusion surround prevailing understandings of men's health, particularly those generated by media debate and public policy, and health research has often operated on oversimplified assumptions about men and masculinity. A more useful way of understanding men's health is to adopt a gender-relations approach. This means examining health concerns in the context of men's and women's interactions with each other, and their positions in the larger, multidimensional structure of gender relations. Such an approach raises the issue of differences among men, which is a key issue in recent research on masculinity and an important health issue. The gender-relations approach offers new ways of addressing practical issues of healthcare for men in college environments.

Heterologous embryo transfer: Magisterial answers and metaphysical questions.

PubMed

Accad, Michel

2014-02-01

The debate regarding the morality of heterologous embryo transfer (HET) as a solution for the fate of cryopreserved embryos remains active. This paper endeavors to show that the magisterial instructions on bioethical issues can only lead to the conclusion that HET is always morally illicit. I begin by showing that the text of Dignitas personae recognizes HET as a procedure accomplishing a procreative function, and I indicate that it is through gestation that this procreative function occurs. I further show that the previous Instruction, Donum vitae, implicitly points to an ontological or spiritual consideration at play during gestation. This consideration is likely related to the procreative function identified in Dignitas personae. Finally, I place these two textual arguments in the context of the debate concerning HET and conclude that metaphysical questions must be clarified in order for the immorality of HET to be understood from a suitable anthropological perspective and gain more widespread acceptance.

Heterologous embryo transfer: Magisterial answers and metaphysical questions

PubMed Central

Accad, Michel

2014-01-01

The debate regarding the morality of heterologous embryo transfer (HET) as a solution for the fate of cryopreserved embryos remains active. This paper endeavors to show that the magisterial instructions on bioethical issues can only lead to the conclusion that HET is always morally illicit. I begin by showing that the text of Dignitas personae recognizes HET as a procedure accomplishing a procreative function, and I indicate that it is through gestation that this procreative function occurs. I further show that the previous Instruction, Donum vitae, implicitly points to an ontological or spiritual consideration at play during gestation. This consideration is likely related to the procreative function identified in Dignitas personae. Finally, I place these two textual arguments in the context of the debate concerning HET and conclude that metaphysical questions must be clarified in order for the immorality of HET to be understood from a suitable anthropological perspective and gain more widespread acceptance. PMID:24899737

Local or distributed activation? The view from biology

NASA Astrophysics Data System (ADS)

Reimers, Mark

2011-06-01

There is considerable disagreement among connectionist modellers over whether to represent distinct properties by distinct nodes of a network or whether properties should be represented by patterns of activity across all nodes. This paper draws on the literature of neuroscience to say that a more subtle way of describing how different brain regions contribute to a behaviour, in terms of individual learning and in terms of degrees of importance, may render the current debate moot: both sides of the 'localist' versus 'distributed' debate emphasise different aspects of biology.

Stimulating debate: ethics in a multidisciplinary functional neurosurgery committee

PubMed Central

Ford, Paul J; Kubu, Cynthia S

2006-01-01

Multidisciplinary healthcare committees meet regularly to discuss patients' candidacy for emerging functional neurosurgical procedures, such as Deep Brain Stimulation (DBS). Through debate and discussion around the surgical candidacy of particular patients, functional neurosurgery programs begin to mold practice and policy supported both by scientific evidence and clear value choices. These neurosurgical decisions have special considerations not found in non‐neurologic committees. The professional time used to resolve these conflicts provides opportunities for the emergence of careful, ethical practices simultaneous with the expansion of therapy applications PMID:16446416

The Extension of Belgium's Euthanasia Law to Include Competent Minors.

PubMed

Raus, Kasper

2016-06-01

Following considerable debate, the practice of euthanasia was legalized in Belgium in 2002, thereby making Belgium one of the few places in the world where this practice is legal. In 2014 the law was amended for the first time. The 2014 amendment makes euthanasia legally possible for all minors who repeatedly and voluntarily request euthanasia and who are judged to possess "capacity of discernment" (regardless of their biological age), as well as fulfil a number of other criteria of due care. This extension of the 2002 euthanasia law generated a lot of national and international debate and has been applauded by many and heavily criticized by others. This evolution is clearly of interest to end-of-life debates in the entire world. This paper will therefore describe how this amendment came to get passed using official documents from Belgium's Senate and Chamber of Representatives where this amendment was discussed and subsequently passed. Next, some of the most commonly given arguments in favour of the law are identified, as well as the arguments most often voiced against the amendment. All these arguments will be expanded upon and it will be examined whether they hold up to ethical scrutiny. Analysing the official documents and identifying the most commonly voiced arguments gives valuable insight into how Belgium came to amend its euthanasia law and why it did so in 2014. It also becomes clear that although the current amendment is often seen as far-reaching, more radical ideas were proposed during the drafting of the law. Also, in analysing those arguments in favour of the amendment and those against, it is clear that the validity of some of these is questionable.

The WISDOM Study: breaking the deadlock in the breast cancer screening debate.

PubMed

Esserman, Laura J

2017-01-01

There are few medical issues that have generated as much controversy as screening for breast cancer. In science, controversy often stimulates innovation; however, the intensely divisive debate over mammographic screening has had the opposite effect and has stifled progress. The same two questions-whether it is better to screen annually or bi-annually, and whether women are best served by beginning screening at 40 or some later age-have been debated for 20 years, based on data generated three to four decades ago. The controversy has continued largely because our current approach to screening assumes all women have the same risk for the same type of breast cancer. In fact, we now know that cancers vary tremendously in terms of timing of onset, rate of growth, and probability of metastasis. In an era of personalized medicine, we have the opportunity to investigate tailored screening based on a woman's specific risk for a specific tumor type, generating new data that can inform best practices rather than to continue the rancorous debate. It is time to move from debate to wisdom by asking new questions and generating new knowledge. The WISDOM Study (Women Informed to Screen Depending On Measures of risk) is a pragmatic, adaptive, randomized clinical trial comparing a comprehensive risk-based, or personalized approach to traditional annual breast cancer screening. The multicenter trial will enroll 100,000 women, powered for a primary endpoint of non-inferiority with respect to the number of late stage cancers detected. The trial will determine whether screening based on personalized risk is as safe, less morbid, preferred by women, will facilitate prevention for those most likely to benefit, and adapt as we learn who is at risk for what kind of cancer. Funded by the Patient Centered Outcomes Research Institute, WISDOM is the product of a multi-year stakeholder engagement process that has brought together consumers, advocates, primary care physicians, specialists, policy makers, technology companies and payers to help break the deadlock in this debate and advance towards a new, dynamic approach to breast cancer screening.

Giant Landslides, Mega-Tsunamis, and Paleo-Sea Level in the Hawaiian Islands

NASA Astrophysics Data System (ADS)

Watts, P.; McMurtry, G. M.; Fryer, G. J.; Smith, J. R.; Imamura, F.

2001-12-01

We show considerable agreement between the ages of the two giant Alika landslides and dating of debris found tens to hundreds of meters above sea level in Hawaii. Despite the size of the landslides, controversy persists as to the ability to generate landslide tsunamis big enough to deposit the debris. We affirm that tsunami deposits are a sufficient explanation of the observed pattern of debris height. We also show that our tsunami simulations can be used to reduce the considerable uncertainty in subsidence history of the different Hawaiian islands, a current obstacle to interpreting the supposed deposits. Finally, we show that the onset of interglacials provides a probable explanation for the timing of these giant landslides over the last five million years. We predict that the greatest tsunami hazard facing the Hawaiian islands are giant landslides and that the current interglacial promotes the generation of mega-tsunamis from catastrophic volcano collapse. Hawaiian giant submarine landslide events have been recognized from detached submarine landslide blocks and fields of smaller debris by offshore surveys. Mega-tsunamis produced by giant landslides were first proposed for Hawaii and have since been implicated globally at other oceanic islands and along the continental margins. While not discounting the possibility of locally-generated tsunamis, some researchers have cast doubt upon the original hypothesis of giant waves impacting Lanai and other Hawaiian islands from flank failures of the nearby Mauna Loa Volcano on Hawaii island. Landslide tsunami simulations have advanced to the point where the tsunamigenic potential of the giant submarine landslides can be affirmed, while the subsidence history of different Hawaiian islands is still subject to debate.

The Developmental Origins of Health and Disease and Sustainable Development Goals: mapping the way forward.

PubMed

Kajee, N; Sobngwi, E; Macnab, A; Daar, A S

2018-02-01

In this paper, meant to stimulate debate, we argue that there is considerable benefit in approaching together the implementation of two seemingly separate recent developments. First, on the global development agenda, we have the United Nations General Assembly's 2015 finalized list of 17 Sustainable Development Goals (SDGs). Several of the SDGs are related to health. Second, the field of Developmental Origins of Health and Disease (DOHaD) has garnered enough compelling evidence demonstrating that early exposures in life affect not only future health, but that the effects of that exposure can be transmitted across generations - necessitating that we begin to focus on prevention. We argue that implementing the SDGs and DOHaD together will be beneficial in several ways; and will require attending to multiple, complex and multidisciplinary approaches as we reach the point of translating science to policy to impact. Here, we begin by providing the context for our work and making the case for a mutually reinforcing, synergistic approach to implementing SDGs and DOHaD, particularly in Africa. To do this, we initiate discussion via an early mapping of some of the overlapping considerations between SDGs and DOHaD.

Responsible, Inclusive Innovation and the Nano-Divide.

PubMed

Schroeder, Doris; Dalton-Brown, Sally; Schrempf, Benjamin; Kaplan, David

Policy makers from around the world are trying to emulate successful innovation systems in order to support economic growth. At the same time, innovation governance systems are being put in place to ensure a better integration of stakeholder views into the research and development process. In Europe, one of the most prominent and newly emerging governance frameworks is called Responsible Research and Innovation (RRI). This article aims to substantiate the following points: (1) The concept of RRI and the concept of justice can be used to derive similar ethical positions on the nano-divide. (2) Given the ambitious policy aims of RRI (e.g. economic competitiveness enhancer), the concept may be better suited to push for ethical outcomes on access to nanotechnology and its products rather than debates based on justice issues alone. It may thus serve as a mediator concept between those who push solely for competitiveness considerations and those who push solely for justice considerations in nano-technology debates. (3) The descriptive, non-normative Systems of Innovation approaches (see below) should be linked into RRI debates to provide more evidence on whether the approach advocated to achieve responsible and ethical governance of research and innovation (R&I) can indeed deliver on competitiveness (in nano-technology and other fields).

Gender and the transmission of civic engagement: assessing the influences on youth civic activity.

PubMed

Matthews, Todd L; Hempel, Lynn M; Howell, Frank M

2010-01-01

The study of civic activity has become a central focus for many social scientists over the past decade, generating considerable research and debate. Previous studies have largely overlooked the role of youth socialization into civic life, most notably in the settings of home and school. Further, differences along gender lines in civic capacity have not been given sufficient attention in past studies. This study adds to the literature by examining the potential pathways in the development of youth civic activity and potential, utilizing both gender-neutral and gender-specific structural equation modeling of data from the 1996 National Household Education Survey. Results indicate that involvement by parents in their child's schooling plays a crucial, mediating role in the relationship between adult and youth civic activity. Gender differences are minimal; thus adult school involvement is crucial for transmitting civic culture from parents to both female and male youth.

From anatomical 'competence' to complex capability. The views and experiences of UK tutors on how we should teach anatomy to medical students.

PubMed

Regan de Bere, Sam; Mattick, Karen

2010-10-01

Developments in clinical education have recently challenged the identity of anatomy teaching and learning, leading to high profile debate over the potential implications for the competence levels of new doctors. However, the emphasis remains on methods of teaching, rather than a review of what well-rounded anatomical learning actually entails, and how teaching can address contemporary learning needs. This paper identifies and addresses some of these issues, drawing on expert views captured in qualitative research with anatomy tutors at twenty different medical schools in the UK. Three main themes emerging from our analysis are described: anatomy as a subject matter, the challenges of teaching or learning anatomy, and the use of teaching methods. We also detail how inductive analysis generated new hypotheses worthy of further consideration. These fall into two key categories: (1) improving anatomy curriculum design and (2) advancing anatomy education research.

Introducing a standard of legal insanity: The case of Sweden compared to The Netherlands.

PubMed

Radovic, Susanna; Meynen, Gerben; Bennet, Tova

2015-01-01

A recent governmental report has suggested that the notion of insanity, which has not been a relevant concept in Swedish criminal law for the last 50years, should be reintroduced into the criminal justice system. This move has generated a debate over the most appropriate criteria to be included in a legal standard for insanity. We consider the fundamental question of whether a legal standard is required when introducing insanity, by looking at a legal system in which legal insanity is available but where no standard is used: The Netherlands. Overall, a review of advantages and disadvantages leads to the conclusion that such a standard is necessary. What exactly should that standard be? Is the development of different "grades" of insanity desirable? Legal considerations concerning what is essentially a legal notion should predominate in making these determinations-informed by psychiatric and other relevant scientific findings. Copyright © 2015. Published by Elsevier Ltd.

Propofol-Related Infusion Syndrome in Critically Ill Pediatric Patients: Coincidence, Association, or Causation?

PubMed Central

Timpe, Erin M.; Eichner, Samantha F.; Phelps, Stephanie J.

2006-01-01

Over the past two decades numerous reports have described the development of a propofol-related infusion syndrome (PRIS) in critically ill adult and pediatric patients who received continuous infusion propofol for anesthesia or sedation. The syndrome is generally characterized by progressive metabolic acidosis, hemodynamic instability and bradyarrhythmias that are refractory to aggressive pharmacological treatments. PRIS may occur with or without the presence of hepatomegaly, rhabdomyolysis or lipemia. To date, the medical literature contains accounts of 20 deaths in critically ill pediatric patients who developed features consistent with PRIS. These reports have generated considerable discussion and debate regarding the relationship, if any, between propofol and a constellation of clinical symptoms and features that have been attributed to its use in critically ill pediatric patients. This paper reviews the literature concerning PRIS, its clinical presentation, proposed mechanisms for the syndrome, and potential management should the syndrome occur. PMID:23118644

The impact of prescription opioids on all-cause mortality in Canada.

PubMed

Imtiaz, Sameer; Rehm, Jürgen

2016-08-01

An influential study from the United States generated considerable discussion and debate. This study documented rising morbidity and mortality in midlife among white non-Hispanic Americans in the 21st century, with clear linkages of all-cause mortality to increasing rates of poisonings, suicides and chronic liver disease deaths. All of these causes of deaths are strongly related to the use of legal and illegal substances, but the study stressed the importance of prescription opioids. Given the similarities between the United States and Canada in prescription opioid use, the assessment of similar all-cause mortality trends is relevant for Canada. As this commentary highlights, the all-cause mortality shifts seen in the United States cannot be seen in Canada for either sex or age groups. The exact reasons for the differences between the two countries are not clear, but it is important for public health to further explore this question.

Basic concepts of depression

PubMed Central

Paykel, Eugene S.

2008-01-01

This paper reviews concepts of depression, including history and classification. The original broad concept of melancholia included all forms of quiet insanity. The term depression began to appear in the nineteenth century as did the modern concept of affective disorders, with the core disturbance now viewed as one of mood. The 1930s saw the introduction of defined criteria into official diagnostic schemes. The modern separation into unipolar and bipolar disorder was introduced following empirical research by Angst and Perris in the 1960s. The partially overlapping distinctions between psychotic and neurotic depression, and between endogenous and reactive depression, started to generate debate in the 1920s, with considerable multivariate research in the 1960s. The symptom element in endogenous depression currently survives in melancholia or somatic syndrome. Life stress is common in various depressive pictures. Dysthymia, a valuable diagnosis, represents a form of what was regarded earlier as neurotic depression. Other subtypes are also discussed. PMID:18979941

Enhanced spin–orbit torques by oxygen incorporation in tungsten films

PubMed Central

Demasius, Kai-Uwe; Phung, Timothy; Zhang, Weifeng; Hughes, Brian P.; Yang, See-Hun; Kellock, Andrew; Han, Wei; Pushp, Aakash; Parkin, Stuart S. P.

2016-01-01

The origin of spin–orbit torques, which are generated by the conversion of charge-to-spin currents in non-magnetic materials, is of considerable debate. One of the most interesting materials is tungsten, for which large spin–orbit torques have been found in thin films that are stabilized in the A15 (β-phase) structure. Here we report large spin Hall angles of up to approximately –0.5 by incorporating oxygen into tungsten. While the incorporation of oxygen into the tungsten films leads to significant changes in their microstructure and electrical resistivity, the large spin Hall angles measured are found to be remarkably insensitive to the oxygen-doping level (12–44%). The invariance of the spin Hall angle for higher oxygen concentrations with the bulk properties of the films suggests that the spin–orbit torques in this system may originate dominantly from the interface rather than from the interior of the films. PMID:26912203

The Recent Atlantic Cold Anomaly: Causes, Consequences, and Related Phenomena

NASA Astrophysics Data System (ADS)

Josey, Simon A.; Hirschi, Joel J.-M.; Sinha, Bablu; Duchez, Aurélie; Grist, Jeremy P.; Marsh, Robert

2018-01-01

Cold ocean temperature anomalies have been observed in the mid- to high-latitude North Atlantic on interannual to centennial timescales. Most notably, a large region of persistently low surface temperatures accompanied by a sharp reduction in ocean heat content was evident in the subpolar gyre from the winter of 2013-2014 to 2016, and the presence of this feature at a time of pervasive warming elsewhere has stimulated considerable debate. Here, we review the role of air-sea interaction and ocean processes in generating this cold anomaly and place it in a longer-term context. We also discuss the potential impacts of surface temperature anomalies for the atmosphere, including the North Atlantic Oscillation and European heat waves; contrast the behavior of the Atlantic with the extreme warm surface event that occurred in the North Pacific over a similar timescale; and consider the possibility that these events represent a response to a change in atmospheric planetary wave forcing.

Midcingulate Motor Map and Feedback Detection: Converging Data from Humans and Monkeys

PubMed Central

Procyk, Emmanuel; Wilson, Charles R. E.; Stoll, Frederic M.; Faraut, Maïlys C. M.; Petrides, Michael; Amiez, Céline

2016-01-01

The functional and anatomical organization of the cingulate cortex across primate species is the subject of considerable and often confusing debate. The functions attributed to the midcingulate cortex (MCC) embrace, among others, feedback processing, pain, salience, action-reward association, premotor functions, and conflict monitoring. This multiplicity of functional concepts suggests either unresolved separation of functional contributions or integration and convergence. We here provide evidence from recent experiments in humans and from a meta-analysis of monkey data that MCC feedback-related activity is generated in the rostral cingulate premotor area by specific body maps directly related to the modality of feedback. As such, we argue for an embodied mechanism for adaptation and exploration in MCC. We propose arguments and precise tools to resolve the origins of performance monitoring signals in the medial frontal cortex, and to progress on issues regarding homology between human and nonhuman primate cingulate cortex. PMID:25217467

[Debating disease: the risk factor concept in political economic and scientific consideration, 1968 to 1986].

PubMed

Madarász, Jeannette

2009-01-01

The risk factor concept was developed in American epidemiological studies ongoing since the 1940s researching the causes of chronic cardiovascular diseases. By looking at the depiction of this model in a variety of media in Germany between 1968 and 1986 we can put its close interaction with contemporary socio-political debates under scrutiny. Thereby, a strong connection between the various agents' political and economic interests on the one hand and the incorporation of the risk factor concept into their specific agendas will become apparent. The risk factor concept was not fundamentally changed in the process but it was adapted to contemporary conditions and political constellations. Thereby, so it will be argued, the medical uses of the model, especially regarding the prevention of chronic cardiovascular disease, were forced into the background of public debates.

LEGAL ISSUES OF GEOGRAPHIC INFORMATION SYSTEMS

EPA Science Inventory

Legal issues are becoming as important as any other in promoting or limiting the development of GIS technology. Certainly legal considerations must now be kept in mind during the creation and implementation of large public and private GIS projects. Debate focuses on a number of...

A perspective on livestock-wolf interactions on western rangelands

USDA-ARS?s Scientific Manuscript database

The reintroduction of wolves into their historical ranges in western North America is possibly one of the most ambitious ecosystem restoration efforts of the recent past. This initiative has been controversial and has stimulated considerable debate among concerned stakeholders about the feasibility ...

Symbolic Representation of Probabilistic Worlds

ERIC Educational Resources Information Center

Feldman, Jacob

2012-01-01

Symbolic representation of environmental variables is a ubiquitous and often debated component of cognitive science. Yet notwithstanding centuries of philosophical discussion, the efficacy, scope, and validity of such representation has rarely been given direct consideration from a mathematical point of view. This paper introduces a quantitative…

Debating science policy in the physics classroom.

NASA Astrophysics Data System (ADS)

Mayer, Shannon

2010-03-01

It is critically important that national and international science policy be scientifically grounded. To this end, the next generation of scientists and engineers will need to be technically competent, effective communicators of science, and engaged advisors in the debate and formulation of science policy. We describe three science policy debates developed for the physics classroom aimed at encouraging students to draw connections between their developing technical expertise and important science policy issues. The first debate considers the proposal for a 450-megawatt wind farm on public lands in Nantucket Sound and fits naturally into the curriculum related to alternative forms of energy production. The second debate considers national fuel-economy standards for sport-utility vehicles and can be incorporated into the curriculum related to heat engines. The third debate, suitable for the curriculum in optics, considers solid state lighting and implications of recent United States legislation that places stringent new energy-efficiency and reliability requirements on conventional lighting. The technical foundation for each of these debates fits naturally into the undergraduate physics curriculum and the material is suitable for a wide range of physics courses, including general science courses for non-majors.

Teaching the Nation's Story: Comparing Public Debates and Classroom Perspectives on History Education in Australia and Canada

ERIC Educational Resources Information Center

Clark, Anna

2009-01-01

Teaching national history in school generates significant public anxiety and political debate--as the various "history wars" around the world reveal. For many school students, however, studying their nation's past is dull and repetitive. Such lack of interest has been confirmed by surveys and research reports that reveal alarmingly low…

Spontaneous Number Representation in Mosquitofish

ERIC Educational Resources Information Center

Dadda, Marco; Piffer, Laura; Agrillo, Christian; Bisazza, Angelo

2009-01-01

While there is convincing evidence that preverbal human infants and non-human primates can spontaneously represent number, considerable debate surrounds the possibility that such capacity is also present in other animals. Fish show a remarkable ability to discriminate between different numbers of social companions. Previous work has demonstrated…

New Developments in Education for the Seventies.

ERIC Educational Resources Information Center

Spaulding, Seth

Theories relating to proposed improvements in education are discussed. Changes in curricula, contributions of fields such as psychology, and issues currently being debated are given consideration. Innovative models and approaches are proposed, and several interesting speculations are offered related to the future of education. Following the…

International Large-Scale Assessments: What Uses, What Consequences?

ERIC Educational Resources Information Center

Johansson, Stefan

2016-01-01

Background: International large-scale assessments (ILSAs) are a much-debated phenomenon in education. Increasingly, their outcomes attract considerable media attention and influence educational policies in many jurisdictions worldwide. The relevance, uses and consequences of these assessments are often the focus of research scrutiny. Whilst some…

Curricular Transposition in Citizenship Education

ERIC Educational Resources Information Center

McCowan, Tristan

2008-01-01

The considerable debate in recent years on the aims of citizenship education has not been accompanied by an equally substantial discussion on the educational processes involved. This article puts forward a theoretical framework, referred to as "curricular transposition", for understanding the complex task of realizing normative ideals of…

Parallel Acquisition of Awareness and Differential Delay Eyeblink Conditioning

ERIC Educational Resources Information Center

Weidemann, Gabrielle; Antees, Cassandra

2012-01-01

There is considerable debate about whether differential delay eyeblink conditioning can be acquired without awareness of the stimulus contingencies. Previous investigations of the relationship between differential-delay eyeblink conditioning and awareness of the stimulus contingencies have assessed awareness after the conditioning session was…

Framing and the health policy process: a scoping review.

PubMed

Koon, Adam D; Hawkins, Benjamin; Mayhew, Susannah H

2016-07-01

Framing research seeks to understand the forces that shape human behaviour in the policy process. It assumes that policy is a social construct and can be cast in a variety of ways to imply multiple legitimate value considerations. Frames provide the cognitive means of making sense of the social world, but discordance among them forms the basis of policy contestation. Framing, as both theory and method, has proven to generate considerable insight into the nature of policy debates in a variety of disciplines. Despite its salience for understanding health policy debates; however, little is known about the ways frames influence the health policy process. A scoping review using the Arksey and O'Malley framework was conducted. The literature on framing in the health sector was reviewed using nine health and social science databases. Articles were included that explicitly reported theory and methods used, data source(s), at least one frame, frame sponsor and evidence of a given frame's effect on the health policy process. A total of 52 articles, from 1996 to 2014, and representing 12 countries, were identified. Much of the research came from the policy studies/political science literature (n = 17) and used a constructivist epistemology. The term 'frame' was used as a label to describe a variety of ideas, packaged as values, social problems, metaphors or arguments. Frames were characterized at various levels of abstraction ranging from general ideological orientations to specific policy positions. Most articles presented multiple frames and showed how actors advocated for them in a highly contested political process. Framing is increasingly an important, yet overlooked aspect of the policy process. Further analysis on frames, framing processes and frame conflict can help researchers and policymakers to understand opaque and highly charged policy issues, which may facilitate the resolution of protracted policy controversies. © The Author 2016. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine.

Framing and the health policy process: a scoping review

PubMed Central

Koon, Adam D; Hawkins, Benjamin; Mayhew, Susannah H

2016-01-01

Framing research seeks to understand the forces that shape human behaviour in the policy process. It assumes that policy is a social construct and can be cast in a variety of ways to imply multiple legitimate value considerations. Frames provide the cognitive means of making sense of the social world, but discordance among them forms the basis of policy contestation. Framing, as both theory and method, has proven to generate considerable insight into the nature of policy debates in a variety of disciplines. Despite its salience for understanding health policy debates; however, little is known about the ways frames influence the health policy process. A scoping review using the Arksey and O’Malley framework was conducted. The literature on framing in the health sector was reviewed using nine health and social science databases. Articles were included that explicitly reported theory and methods used, data source(s), at least one frame, frame sponsor and evidence of a given frame’s effect on the health policy process. A total of 52 articles, from 1996 to 2014, and representing 12 countries, were identified. Much of the research came from the policy studies/political science literature (n = 17) and used a constructivist epistemology. The term ‘frame’ was used as a label to describe a variety of ideas, packaged as values, social problems, metaphors or arguments. Frames were characterized at various levels of abstraction ranging from general ideological orientations to specific policy positions. Most articles presented multiple frames and showed how actors advocated for them in a highly contested political process. Framing is increasingly an important, yet overlooked aspect of the policy process. Further analysis on frames, framing processes and frame conflict can help researchers and policymakers to understand opaque and highly charged policy issues, which may facilitate the resolution of protracted policy controversies. PMID:26873903

Co-existence of GM, conventional and organic crops in developing countries: Main debates and concerns.

PubMed

Azadi, Hossein; Taube, Friedhelm; Taheri, Fatemeh

2017-06-05

The co-existence approach of GM crops with conventional agriculture and organic farming as a feasible agricultural farming system has recently been placed in the center of hot debates at the EU-level and become a source of anxiety in developing countries. The main promises of this approach is to ensure "food security" and "food safety" on the one hand, and to avoid the adventitious presence of GM crops in conventional and organic farming on the other, as well as to present concerns in many debates on implementing the approach in developing countries. Here, we discuss the main debates on ("what," "why," "who," "where," "which," and "how") applying this approach in developing countries and review the main considerations and tradeoffs in this regard. The paper concludes that a peaceful co-existence between GM, conventional, and organic farming is not easy but is still possible. The goal should be to implement rules that are well-established proportionately, efficiently and cost-effectively, using crop-case, farming system-based and should be biodiversity-focused ending up with "codes of good agricultural practice" for co-existence.

The Power of Debate: Reflections on the Potential of Debates for Engaging Students in Critical Thinking about Controversial Geographical Topics

ERIC Educational Resources Information Center

Healey, Ruth L.

2012-01-01

Many controversial subjects characterize geography in the 21st century. Issues such as climate change, sustainability and social exclusion generate much discussion and often involve clear differences in opinion of how they might be addressed. Higher education is an important space for critical engagement with challenging issues. Preparing for and…

Impact of the French 3rd and 4th generation pill scare in women seeking termination of pregnancy.

PubMed

Caillot, O; Aubry, M; Duros, S; Boyer, L; Van Valenberg, C; Levêque, J; Lavoué, V

2017-01-01

The aim of this study was to evaluate changes in the contraceptive profile of women seeking termination of pregnancy following the debate on 3rd and 4th generation pills in France in 2012. Single-center case-control study comparing the attitude to contraception before (between 02/15/2012 and 07/16/2012) and after the debate (between 02/25/2013 and 06/24/2013). A total of 291 patients consulted before and 601 after the debate. We showed that there were more students (+9.5%), more single women (+8.3%) and fewer working women (-7.7%) in the cohort after the debate. After the termination procedure, prescriptions for long-acting reversible contraceptive (LARC) methods increased (+7.8%, P=0.03), in particular in patients aged 25 or younger, including nulliparous (+12.6%, P=0.02). The media alert about the pill led to a change in the contraceptive standard in the post-abortion period and altered patient profiles. An increase was notably observed in certain vulnerable populations (high school students, unemployed and single women). It remains to be seen whether these changes are transient or permanent. Copyright © 2016. Published by Elsevier Masson SAS.

A framework for analysis of research risks and benefits to participants in standard of care pragmatic clinical trials.

PubMed

Chen, Stephanie C; Kim, Scott Yh

2016-12-01

Standard of care pragmatic clinical trials that compare treatments already in use could improve care and reduce costs, but there is considerable debate about the research risks of standard of care pragmatic clinical trials and how to apply informed consent regulations to such trials. We sought to develop a framework integrating the insights from opposing sides of the debate. We developed a formal risk-benefit analysis framework for standard of care pragmatic clinical trials and then applied it to key provisions of the US federal regulations. Our formal framework for standard of care pragmatic clinical trial risk-benefit analysis takes into account three key considerations: the ex ante estimates of risks and benefits of the treatments to be compared in a standard of care pragmatic clinical trial, the allocation ratios of treatments inside and outside such a trial, and the significance of some participants receiving a different treatment inside a trial than outside the trial. The framework provides practical guidance on how the research ethics regulations on informed consent should be applied to standard of care pragmatic clinical trials. Our proposed formal model makes explicit the relationship between the concepts used by opposing sides of the debate about the research risks of standard of care pragmatic clinical trials and can be used to clarify the implications for informed consent. © The Author(s) 2016.

Toward a gender-sensitive assisted reproduction policy.

PubMed

Donchin, Anne

2009-01-01

The recent case of the UK woman who lost her legal struggle to be impregnated with her own frozen embryos, raises critical issues about the meaning of reproductive autonomy and the scope of regulatory practices. I revisit this case within the context of contemporary debate about the moral and legal dimensions of assisted reproduction. I argue that the gender neutral context that frames discussion of regulatory practices is unjust unless it gives appropriate consideration to the different positions women and men occupy in relation to reproductive processes and their options for autonomous choice. First, I consider relevant legal rulings, media debate, and scholarly commentary. Then I discuss the concept of reproductive autonomy imbedded in this debate. I argue that this concept conflates informed consent and reproductive autonomy, thereby providing an excessively narrow reading of autonomy that fails to give due regard to relations among individuals or the social, political and economic environment that shapes their options. I contrast this notion of autonomy with feminist formulations that seek to preserve respect for the agency of individuals without severing them from the conditions of their embodiment, their surrounding social relationships, or the political contexts that shape their options. Taking these considerations into account I weigh the advantages of regulation over the commercial market arrangement that prevails in some countries and suggest general guidelines for a regulatory policy that would more equitably resolve conflicting claims to reproductive autonomy.

Relating the Content and Confidence of Recognition Judgments

ERIC Educational Resources Information Center

Selmeczy, Diana; Dobbins, Ian G.

2014-01-01

The Remember/Know procedure, developed by Tulving (1985) to capture the distinction between the conscious correlates of episodic and semantic retrieval, has spawned considerable research and debate. However, only a handful of reports have examined the recognition content beyond this dichotomous simplification. To address this, we collected…

Honey bee queens do not count mates to assess their mating success

USDA-ARS?s Scientific Manuscript database

The mating system of honey bees (genus Apis) is extremely polyandrous, where reproductive females (queens) typically mate with 12 or more males (drones) during their mating flight(s). The evolutionary implications for hyperpolyandry have been subject to considerable debate and empirical testing beca...

Whither Constructivism?--A Chemistry Teachers' Perspective

ERIC Educational Resources Information Center

Niaz, Mansoor

2008-01-01

Constructivism in science education has been the subject of considerable debate in the science education literature. The purpose of this study was to facilitate chemistry teachers' understanding that the tentative nature of scientific knowledge leads to the coexistence and rivalries among different forms of constructivism in science education. The…

Some Pre-Methodological Considerations in Foreign-Language Teaching.

ERIC Educational Resources Information Center

Higgs, Theodore V.

1981-01-01

Combines studies in cognitive psychology and language acquisition with observations of pedagogical materials and student performance to analyze foreign-language teaching from the perspective of what students and teachers need to understand about language learning and language before meaningful debate over methodology can be undertaken. (Author/MES)

Textbooks: What's at Stake?

ERIC Educational Resources Information Center

Focus in Change, 1992

1992-01-01

Textbooks have an enormous influence on the curriculum of schools across the nation. Many issues are taken into consideration when selecting textbooks. Textbooks that present students with a multicultural curriculum are often at the center of debate among school administrators. This journal presents a series of articles based on interviews with…

Language-Universal Sensory Deficits in Developmental Dyslexia: English, Spanish, and Chinese

ERIC Educational Resources Information Center

Goswami, Usha; Wang, H.-L. Sharon; Cruz, Alicia; Fosker, Tim; Mead, Natasha; Huss, Martina

2011-01-01

Studies in sensory neuroscience reveal the critical importance of accurate sensory perception for cognitive development. There is considerable debate concerning the possible sensory correlates of "phonological processing", the primary cognitive risk factor for developmental dyslexia. Across languages, children with dyslexia have a specific…

Comparative and Familial Analysis of Handedness in Great Apes

ERIC Educational Resources Information Center

Hopkins, William D.

2006-01-01

Historically, population-level handedness has been considered a hallmark of human evolution. Whether nonhuman primates exhibit population-level handedness remains a topic of considerable debate. This paper summarizes published data on handedness in great apes. Comparative analysis indicated that chimpanzees and bonobos show population-level right…

University Chaplaincy Provisions: Taking the Religion Out?

ERIC Educational Resources Information Center

Hunt, Stephen

2013-01-01

Albeit fragmented and largely uncoordinated, there is currently considerable debate regarding the nature and rationale of university chaplaincy provisions in England and Wales. Clearly chaplaincies have repositioned themselves from an exclusively Christian ethical and service-based provider to cater for the challenging demands of a multi-faith…

Wheeling and stranded investment-is there a better way

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ferrar, T.

Under current franchise law, retail wheeling must be addressed on a state-by-state basis, and (therefore) it will not sweep the electric power industry as deregulation has been visited upon the telecommunications, airline, natural gas and other industries. Nevertheless, many industry observers remain concerned that retail competition will create a significant stranded investment problem. That is, broadened competition among power generators for customers will result in the market value of some existing (previously market-protected) generation assets falling below book value. The significance of such asset revaluations, and the time required for adjustment, increases with the capital intensity of the industry; thismore » is the reason for the heightened concern regarding the introduction of retail wheeling into the electric power industry. One policy direction that may be worthy of further debate and losses during the power market's transition to a more competitive equilibrium - i.e., until regulation-induced differentials between market and book values are mitigated. A two-part policy proposal is offered for consideration. First, the use of intra-pool transfer payments; second, if stranded investment continues to exist, a temporary uniform pool-wide wheeling surcharge.« less

Fate and Transport of Shale-derived, Biogenic Methane.

PubMed

Hendry, M Jim; Schmeling, Erin E; Barbour, S Lee; Huang, M; Mundle, Scott O C

2017-07-07

Natural gas extraction from unconventional shale gas reservoirs is the subject of considerable public debate, with a key concern being the impact of leaking fugitive natural gases on shallow potable groundwater resources. Baseline data regarding the distribution, fate, and transport of these gases and their isotopes through natural formations prior to development are lacking. Here, we define the migration and fate of CH 4 and δ 13 C-CH 4 from an early-generation bacterial gas play in the Cretaceous of the Williston Basin, Canada to the water table. Our results show the CH 4 is generated at depth and diffuses as a conservative species through the overlying shale. We also show that the diffusive fractionation of δ 13 C-CH 4 (following glaciation) can complicate fugitive gas interpretations. The sensitivity of the δ 13 C-CH 4 profile to glacial timing suggests it may be a valuable tracer for characterizing the timing of geologic changes that control transport of CH 4 (and other solutes) and distinguishing between CH 4 that rapidly migrates upward through a well annulus or other conduit and CH 4 that diffuses upwards naturally. Results of this study were used to provide recommendations for designing baseline investigations.

Food waste generation and industrial uses: A review.

PubMed

Girotto, Francesca; Alibardi, Luca; Cossu, Raffaello

2015-11-01

Food waste is made up of materials intended for human consumption that are subsequently discharged, lost, degraded or contaminated. The problem of food waste is currently on an increase, involving all sectors of waste management from collection to disposal; the identifying of sustainable solutions extends to all contributors to the food supply chains, agricultural and industrial sectors, as well as retailers and final consumers. A series of solutions may be implemented in the appropriate management of food waste, and prioritised in a similar way to waste management hierarchy. The most sought-after solutions are represented by avoidance and donation of edible fractions to social services. Food waste is also employed in industrial processes for the production of biofuels or biopolymers. Further steps foresee the recovery of nutrients and fixation of carbon by composting. Final and less desirable options are incineration and landfilling. A considerable amount of research has been carried out on food waste with a view to the recovery of energy or related products. The present review aims to provide an overview of current debate on food waste definitions, generation and reduction strategies, and conversion technologies emerging from the biorefinery concept. Copyright © 2015 Elsevier Ltd. All rights reserved.

Patient safety is not elective: a debate at the NPSF Patient Safety Congress.

PubMed

McTiernan, Patricia; Wachter, Robert M; Meyer, Gregg S; Gandhi, Tejal K

2015-02-01

The opening keynote session of the 16th Annual National Patient Safety Foundation Patient Safety Congress, held 14-16 May 2014, featured a debate addressing the merits and challenges of accountability with respect to key issues in patient safety. The specific resolution debated was: Certain safety practices should be inviolable, and transgressions should result in penalties, potentially including fines, suspensions, and firing. The themes discussed in the debate are issues that healthcare professionals and leaders commonly struggle with in their day-to-day work. How do we draw a line between systems problems and personal failings? When should clinicians and staff be penalised for failing to follow a known safety protocol? The majority of those who listened to the live debate agreed that it is time to begin holding health professionals accountable when they wilfully or repeatedly violate policies or protocols put in place by their institutions to protect the safety of patients. This article summarises the debate as well as the questions and discussion generated by each side. A video of the original debate can be found at http://bit.ly/Npsf_debate. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Voices from a Small Discipline: How the Australian Vocational Education and Training Discipline Made Sense of Journal Rankings

ERIC Educational Resources Information Center

Smith, Erica

2014-01-01

The topic of quality rankings of academic journals generated a great deal of debate and opinion in Australia during their time at the forefront of interest in the mid-to-late 2000s. However, there has been little empirical research to inform the debate. This paper reports on and analyses the journal ranking experiences of one small…

"Less than a Dog": Interrogating Theatre for Debate in Westville Female Correctional Centre, Durban South Africa

ERIC Educational Resources Information Center

Young-Jahangeer, Miranda

2013-01-01

Incarcerated women at Westville Female Correctional Centre in Durban, South Africa have been using popular participatory theatre (PPT) to create a space to generate debate about aspects of prison life for over 10 years. This article explores how these women engaged the issue of lesbianism in the Correctional Centre and how the process and form was…

Towards a richer debate on tissue engineering: a consideration on the basis of NEST-ethics.

PubMed

Oerlemans, A J M; van Hoek, M E C; van Leeuwen, E; van der Burg, S; Dekkers, W J M

2013-09-01

In their 2007 paper, Swierstra and Rip identify characteristic tropes and patterns of moral argumentation in the debate about the ethics of new and emerging science and technologies (or "NEST-ethics"). Taking their NEST-ethics structure as a starting point, we considered the debate about tissue engineering (TE), and argue what aspects we think ought to be a part of a rich and high-quality debate of TE. The debate surrounding TE seems to be predominantly a debate among experts. When considering the NEST-ethics arguments that deal directly with technology, we can generally conclude that consequentialist arguments are by far the most prominently featured in discussions of TE. In addition, many papers discuss principles, rights and duties relevant to aspects of TE, both in a positive and in a critical sense. Justice arguments are only sporadically made, some "good life" arguments are used, others less so (such as the explicit articulation of perceived limits, or the technology as a technological fix for a social problem). Missing topics in the discussion, at least from the perspective of NEST-ethics, are second "level" arguments-those referring to techno-moral change connected to tissue engineering. Currently, the discussion about tissue engineering mostly focuses on its so-called "hard impacts"-quantifiable risks and benefits of the technology. Its "soft impacts"-effects that cannot easily be quantified, such as changes to experience, habits and perceptions, should receive more attention.

Family Factors and Student Outcomes. PRGS Dissertation

ERIC Educational Resources Information Center

Xia, Nailing

2010-01-01

There is considerable debate about the relative importance of family versus school factors in producing academic and nonacademic student outcomes, and whether and how their impacts vary across different student groups. In addition to critically reviewing and synthesizing earlier work, this study extends the literature by (a) using the ECLS-K, a…

(Re)Considering Normal: Queering Social Norms for Parents and Teachers

ERIC Educational Resources Information Center

Bower, Laura; Klecka, Cari

2009-01-01

Recent debates regarding same-sex marriage and gay and lesbian adoption highlight the role of schools as sociopolitical institutions. Accordingly, teachers operating within social norms have considerable influence through their interactions with students and their families. Previous research points to lesbian, gay, bisexual, and transgender (LGBT)…

Biotechnologies and Human Dignity

ERIC Educational Resources Information Center

Sweet, William; Masciulli, Joseph

2011-01-01

In this article, the authors review some contemporary cases where biotechnologies have been employed, where they have had global implications, and where there has been considerable debate. The authors argue that the concept of dignity, which lies at the center of such documents as the 2005 Universal Declaration on Bioethics and Human Rights, the…

Contesting Global Neoliberalism and Creating Alternative Futures

ERIC Educational Resources Information Center

Hursh, David W.; Henderson, Joseph A.

2011-01-01

Neoliberal policies, in spite of their considerable damage to economic equality, the environment, and education, remain dominant. In this paper, we suggest that neoliberalism has remained dominant in part because the power elite who benefit from the policies have gained control over both public debate and policy-making. By dominating the discourse…

Literacy: An Essential Ingredient in the Recipe for Growth

ERIC Educational Resources Information Center

Murray, Scott

2005-01-01

The ingredients that underpin economic growth are well-known and generally accepted; population growth, physical capital, financial capital and human capital all play a part in creating long term differences in the wealth of nations. There remains, however, considerable debate about the ideal recipe for economic growth. Recently, Statistics Canada…

International Education Comparison: An Intellectual Tradition and Its Contemporary Considerations

ERIC Educational Resources Information Center

Li, Yu-Chih

2017-01-01

What is the nature of comparative and international education as a discipline? What are the relationships and connections between comparison and internationalization? Such questions have long been discussed in comparative education and have provoked much debate."Comparative and International Education: An Introduction to Theory, Method, and…

From Conceptual Frameworks to Mental Models for Astronomy: Students' Perceptions

ERIC Educational Resources Information Center

Pundak, David; Liberman, Ido; Shacham, Miri

2017-01-01

Considerable debate exists among discipline-based astronomy education researchers about how students change their perceptions in science and astronomy. The study questioned the development of astronomical models among students in institutions of higher education by examining how college students change their initial conceptual frameworks and…

The Analysis of the Relation between Education and Economic Growth

ERIC Educational Resources Information Center

Monteils, Marielle

2004-01-01

The debate concerning the various determinants of economic growth has attracted considerable attention. The argument according to which endogenous growth models explain long-term economic growth is often put forward. Particularly, it is held that the production of knowledge by education induces self-sustained growth. In spite of numerous…

Cocos nucifera L

Treesearch

James A. Allen

2002-01-01

The genus Cocos is monotypic. Cocos nucifera is believed to have originated in the Old World tropics, but the natural range is unknown and the origin of the species is the subject of considerable debate (Harries 1978, Parrotta 1993). Dispersal by humans has played a major role in the naturalization of the species on tropical...

Diet composition, dry matter intake and diet overlap of mule deer, elk and cattle.

Treesearch

Scott L. Findholt; Bruce K. Johnson; Daalkhaijav Damiran; Tim DelCurto; John G. Kie

2004-01-01

Mule deer (Odocoileus hemionus), elk (Cervus elaphus) and cattle share rangeland throughout much of interior western North America. Considerable debate exists about the degree to which facilitation or competition occurs for forage between these three species (Nelson 1982, Wisdom and Thomas 1996, Miller 2002).

Being Human: Transdisciplinarity in Nursing

ERIC Educational Resources Information Center

Timmons, Stephen; Edgley, Alison; Meal, Andy; Narayanasamy, Aru

2016-01-01

Nursing as an academic discipline typically draws on a wide range of other disciplines. There is debate about whether this is a sound basis for the discipline, or whether nursing needs to develop a distinctive body of knowledge. The concept of transdisciplinarity, though little discussed in nursing, is of considerable value in understanding…

California spotted owl: scientific considerations for forest planning

Treesearch

John J. Keane

2014-01-01

California spotted owls (Strix occidentalis occidentalis) (fig. 1) have been at the forefront of Sierra Nevada management and conservation debates for 25 years because of their strong habitat associations with commercially valuable large trees, snags, and late-successional forests. Initial concerns focused on the effects of timber harvest on large...

Symbolic Number Skills Predict Growth in Nonsymbolic Number Skills in Kindergarteners

ERIC Educational Resources Information Center

Lyons, Ian M.; Bugden, Stephanie; Zheng, Samuel; De Jesus, Stefanie; Ansari, Daniel

2018-01-01

There is currently considerable discussion about the relative influences of evolutionary and cultural factors in the development of early numerical skills. In particular, there has been substantial debate and study of the relationship between approximate, nonverbal (approximate magnitude system [AMS]) and exact, symbolic (symbolic number system…

Evaluating the use of red light running photographic enforcement using collisions and red light running violations ; Final Report

DOT National Transportation Integrated Search

2004-12-01

The issue of red light running (RLR) has long been a problem throughout the United States. : There is considerable debate within the general public and public agencies regarding the use of : photographic enforcement to deter red light violations. Man...

The Poverty of the Mayan Stimulus

ERIC Educational Resources Information Center

Pye, Clifton

2012-01-01

Poverty of the stimulus (POS) arguments have instigated considerable debate in the recent linguistics literature. This article uses the comparative method to challenge the logic of POS arguments. Rather than question the premises of POS arguments, the article demonstrates how POS arguments for individual languages lead to a "reductio ad absurdum"…

Current Directions in ADHD and Its Treatment

ERIC Educational Resources Information Center

Norvilitis, Jill M., Ed.

2012-01-01

The treatment of Attention Deficit Hyperactivity Disorder is a matter of ongoing research and debate, with considerable data supporting both psychopharmacological and behavioral approaches. Researchers continue to search for new interventions to be used in conjunction with or in place of the more traditional approaches. These interventions run the…

From SRI to ESG: The Changing World of Responsible Investing

ERIC Educational Resources Information Center

Caplan, Lauren; Griswold, John S.; Jarvis, William F.

2013-01-01

Thoughtful investment professionals continue to debate whether a portfolio's long-term performance can be enhanced by including environmental, social, and governance (ESG) considerations in the security selection process, but responsible investing is more than a passing trend. The terms socially-responsible investing, mission-related investing,…

Defending Literacy: With Particular Consideration of the Community College.

ERIC Educational Resources Information Center

Sadock, Geoffrey J.

The broad and highly politicized debate about the causes of rising illiteracy in the nation fall into three categories: nurture, or inadequate elementary/secondary educational institutions; nature, or arguments about genetics and the unteachability of Blacks and other minority groups; and social science, or the idea that standard literacy tests…

The Philosophical Problem of Truth in Librarianship

ERIC Educational Resources Information Center

Labaree, Robert V.; Scimeca, Ross

2008-01-01

The authors develop a framework for addressing the question of truth in librarianship and in doing so attempt to move considerations of truth closer to the core of philosophical debates within the profession. After establishing ways in which philosophy contributes to social scientific inquiry in library science, the authors examine concepts of…

The Missing Link: The Sexualisation of Culture and Men

ERIC Educational Resources Information Center

Garner, Maria

2012-01-01

Whilst debate around the sexualisation of culture proliferates across discursive arenas, the potential meanings and impacts for the lives of women, girls and young people dominates discussion. Meanwhile, consideration of men and masculinities remains scarce or only thinly sketched across the field. This viewpoint explores sexualisation as a…

Tweens' Conceptions of Privacy Online: Implications for Educators

ERIC Educational Resources Information Center

Davis, Katie; James, Carrie

2013-01-01

There is considerable debate about young people's concern for privacy today, given their frequent use of social media to share information and other content about themselves and others. While researchers have investigated the online privacy practices of teens and emerging adults, relatively little is known about the attitudes and behaviors of…

The Analysis of Athletic Performance: Some Practical and Philosophical Considerations

ERIC Educational Resources Information Center

Nelson, Lee J.; Groom, Ryan

2012-01-01

This article presents a hypothetical dialogue between a notational analyst (NA) recently schooled in the positivistic assessment of athletic performance, an "old-school" traditional coach (TC) who favours subjective analysis, and a pragmatic educator (PE). The conversation opens with NA and TC debating the respective value of quantitative and…

Some Nice Relations between Right-Angled Triangles and the Golden Section

ERIC Educational Resources Information Center

Scimone, Aldo

2011-01-01

The international debate about experimental approaches to the teaching and learning mathematics is very current. While number theory lends itself naturally to such approaches, elementary geometry can also provide interesting starting points for creative work in class. This article shows how simple considerations about right triangles and the…

The Health and Welfare of University Students in Britain, 1920-1939

ERIC Educational Resources Information Center

Vernon, Keith

2008-01-01

Throughout the interwar period, there was considerable discussion concerning the health and welfare of university students in Britain, involving university officials, student organizations and government departments. In the light of these debates, there was a significant expansion of amenities for students, which included halls of residence,…

Information Processing and Dynamics in Minimally Cognitive Agents

ERIC Educational Resources Information Center

Beer, Randall D.; Williams, Paul L.

2015-01-01

There has been considerable debate in the literature about the relative merits of information processing versus dynamical approaches to understanding cognitive processes. In this article, we explore the relationship between these two styles of explanation using a model agent evolved to solve a relational categorization task. Specifically, we…

Using 2nd generation tyrosine kinase inhibitors in frontline management of chronic phase chronic myeloid leukemia

PubMed Central

Jayakar, Vishal

2014-01-01

Choices in medicine come with responsibility. With several TKI's (Tyrosine kinase inhibitors) available for front-line management of CML (Chronic Myeloid Leukemia), an astute clinician has to personalise, rationalise and take a pragmatic approach towards selection of the best drug for the ‘patient in question’. Though it is hotly debated as to which TKI will triumph, the truth of this debate lies in individualising treatment rather than a general ‘all size fits all’ approach with imatinib. I personally believe that the second generation TKI's will suit most patient clinical profiles rather than prescribing imatinib to all and I have strived to make a strong case for them in front line treatment of CML. Though Imatinib may remain the first line choice for some patients, my efforts in this debate are mainly geared towards breaking the myth that imatinib is the sole ‘block buster’ on the CML landscape PMID:24665456

The public debate on psychotropic medication and changes in attitudes 1990-2011.

PubMed

Angermeyer, Matthias C; Van der Auwera, Sandra; Matschinger, Herbert; Carta, Mauro G; Baumeister, Sebastian E; Schomerus, Georg

2016-03-01

Over the last 25 years, the appraisal of psychotropic drugs within the scientific community and their representation in the media has changed considerably. The initial optimism in the wake of the introduction of second-generation drugs has increasingly made room for a more critical evaluation of alleged advantages of these drugs. The question arises as to what extent this is reflected in similar changes in the public's attitudes towards psychiatric medication. Three representative population surveys on attitudes towards psychotropic medication were carried out in Germany in 1990 (N = 3075), 2001 (N = 2610) and 2011 (N = 1223), using the same sampling procedure, interview mode and instrument for assessing attitudes. In order to disentangle time-related effects, an age-period-cohort analysis was performed. Over the time period of 21 years, the German public's evaluation of psychotropic medication has become markedly more favourable. This change was mostly due to a period effect, i.e. concurrent influences of the social environment people are exposed to. Changes were much more pronounced in the 1990s, while over the following decade only a small, although statistically significant, increase in the favourable appraisal of medication was found. Age and birth cohort had only a minor effect on public attitudes. Our findings suggest that changes in the evaluation of the effects of psychotropic drugs within the psychiatric community and their representation in the media also affect public opinion. Given the ongoing debate about side effects and efficacy of psychiatric medication, future changes of public opinion can be expected.

Learning through debate during problem-based learning: an active learning strategy.

PubMed

Mumtaz, Sadaf; Latif, Rabia

2017-09-01

We explored medical student's views and perceptions of a series of debates conducted during problem-based learning (PBL) practiced as a part of the Spiral curriculum at the Imam Abdulrahman Bin Faisal University, Saudi Arabia. A series of debates were employed during PBL sessions for second-year female medical students, over the period 2014-2016. Each cohort of students was randomly split into 10 small PBL groups and exposed to weekly PBL activity. Within each group, the students were divided into a proposition half and an opposition half. Students were given 1 wk for debate preparation. The students' responses were recorded on a formulated questionnaire. Descriptive statistics were used to analyze quantitative data, and results are presented as percentages. The usefulness of debate in alleviating potential difficulties in communicating with patients was agreed to by 69% ( n = 126) of participants. That these sessions evoked critical thinking among students was reported by 78% ( n = 142). This series of debates helped 61% ( n = 111) of students to learn effectively about controversial issues. Seventy-one percent ( n = 130) considered that debate promoted argument generation and interpretation skills. Enhanced ability to analyze and research evidence was reported by 59% ( n = 108) of students. One hundred and thirteen students (62%) agreed that debate helped them to improve clinical decision-making, and 75% of students agreed that debates encouraged tolerance toward diverse viewpoints/convincing strategies. The majority of our medical students found debating enhanced analytic decision-making, communication, and critical thinking skills. Copyright © 2017 the American Physiological Society.

The great debate series: surgical treatment of aortic valve abnormalities in children.

PubMed

d'Udekem, Yves; Tweddell, James S; Karl, Tom R

2018-05-01

This article is the latest in an EJCTS series entitled 'The Great Debates'. We have chosen the topic of aortic valve (AoV) surgery in children, with a focus on infants and neonates. The topic was selected due to the significant challenges that AoV problems in the young may present to the surgical team. There are many areas of active controversy, despite the vast accumulated world experience. We have tried to incorporate many of these issues in the questions posed, not claiming to be all-inclusive. The individuals invited to this debate are experts in paediatric valve surgery, with broad and successful clinical experiences on multiple continents. We hope that the facts and opinions presented in this debate will generate interest and discussion and perhaps prove useful in decision-making for future complex valve cases.

Is the Heart a Pressure or Flow Generator? Possible Implications and Suggestions for Cardiovascular Pedagogy

ERIC Educational Resources Information Center

Mitchell, Jamie R.

2015-01-01

In this article, a physiology instructor with primarily a cardiovascular (CV) background has wondered what approach to take, with both novice and senior learners, when it comes to delivering material on the pressure or flow generation of the heart. A debate surrounds the pressure propulsion versus flow generation theories, where some understand…

Using mitogenomic and nuclear ribosomal sequence data to investigate the phylogeny of the Xiphinema americanum species complex

USDA-ARS?s Scientific Manuscript database

Nematodes within the Xiphinema americanum species complex are economically important because they vector nepoviruses which cause considerable damage to a variety of agricultural crops. The taxonomy of X. americanum is controversial, with the number of putative species being the subject of debate. Ac...

Ethical Considerations for Research Involving Boys Diagnosed with Attention-Deficit/Hyperactivity Disorder

ERIC Educational Resources Information Center

Tucker, Leigh Adams; Govender, Kaymarlin

2017-01-01

The "new sociology of childhood" has activated a growing interest in children as social actors and their level of involvement in activities that affect their lives. In the field of research, debate is underway regarding the consent processes and methodological activities that support child participation. This paper highlights…

Mechanisms of Masked Priming: A Meta-Analysis

ERIC Educational Resources Information Center

Van den Bussche, Eva; Van den Noortgate, Wim; Reynvoet, Bert

2009-01-01

The extent to which unconscious information can influence behavior has been a topic of considerable debate throughout the history of psychology. A frequently used method for studying subliminal processing is the masked priming paradigm. The authors focused on studies in which this paradigm was used. Their aim was twofold: first, to assess the…

The Usage of CAUSE in Three Branches of Science

ERIC Educational Resources Information Center

Yang, Bei; Chen, Bin

2016-01-01

Semantic prosody is a concept that has been subject to considerable criticism and debate. One big concern is to what extent semantic prosody is domain or register-related. Previous studies reach the agreement that CAUSE has an overwhelmingly negative meaning in general English. Its semantic prosody remains controversial in academic writing,…

Literacy Education and Orthography in the Spanish Golden Age, 1531-1631

ERIC Educational Resources Information Center

Gómez Camacho, Alejandro; Casado Rodrigo, Jesús

2016-01-01

During the Spanish Golden Age, language was developing fast. An important debate on orthology and orthography was taking place at the time. Many authors posed different proposals for a reform of spelling. The arguments discussed in these works also included educational considerations in favour of their proposals, which makes them an invaluable…

Beyond ADHD: A Consideration of Attention Deficit Hyperactivity Disorder and Pedagogy in Australian Schools

ERIC Educational Resources Information Center

Prosser, Brenton J.

2008-01-01

A psycho-medical discourse that explains behavioural dysfunction through neurological deficit has dominated debate about attention deficit hyperactivity disorder (ADHD). However, if only medical questions are asked, only medical answers will be found, resulting in more or less drug treatment. When behavioural dysfunction results in impairment…

Cognitive Adaptation to the Experience of Social and Cultural Diversity

ERIC Educational Resources Information Center

Crisp, Richard J.; Turner, Rhiannon N.

2011-01-01

Diversity is a defining characteristic of modern society, yet there remains considerable debate over the benefits that it brings. The authors argue that positive psychological and behavioral outcomes will be observed only when social and cultural diversity is experienced in a way that challenges stereotypical expectations and that when this…

A Rationale for Critical Pedagogy in EFL: The Case of Tajikistan

ERIC Educational Resources Information Center

Fredricks, Lori

2007-01-01

As EFL programs become more prevalent throughout the world, the cultural implications of English teaching are more often debated. These cultural considerations are extremely relevant in Islamic cultures, where English education can be viewed as contributing to the influence of Western Christian or secular pedagogy. This potential clash of…

Approval Procedures and Passive Consent Considerations in Research among Young People

ERIC Educational Resources Information Center

de Meyrick, Julian

2005-01-01

Purpose: The intention of this paper is to encourage debate among ethical researchers on this very important issue. Research necessary to underpin health education and health promotion is often controversial and often involves vulnerable populations such as young people and children. It is essential that the rights of these respondents are…

Finance Graduates' Knowledge and Skills Development: Graduate and Employer Perceptions in United Arab Emirates

ERIC Educational Resources Information Center

Al Shayeb, Abdulrahman Mohamed

2013-01-01

There has been considerable debate over the past decades concerning the extent to which finance education has fulfilled employers' and graduates' expectations related to knowledge and skills needed in a changing and challenging business environment. This study seeks to examine whether there are significant differences in expectations between…

Twenty Years of Progress in Violence Risk Assessment

ERIC Educational Resources Information Center

Hanson, R. Karl

2005-01-01

Violence risk assessment has advanced considerably in the last 20 years. In the 1980s, leading professionals questioned the very possibility of valid violence risk assessments; now, many of the major risk factors have been identified, and professional debate focuses on how best to combine these risk factors into meaningful evaluations. An…

Health Lifestyle Theory and the Convergence of Agency and Structure

ERIC Educational Resources Information Center

Cockerham, William C.

2005-01-01

This article utilizes the agency-structure debate as a framework for constructing a health lifestyle theory. No such theory currently exists, yet the need for one is underscored by the fact that many daily lifestyle practices involve considerations of health outcomes. An individualist paradigm has influenced concepts of health lifestyles in…

Examining the Role of Corporate Sponsorship in the Public School System: Appropriate Pathways

ERIC Educational Resources Information Center

Potter, Maria

2012-01-01

To compensate for declining public school budgets, an increasing number of local public education organizations are soliciting and accepting financial support from U.S. corporations. There is considerable debate as to whether corporate involvement ultimately aids or hampers students' academic achievement, and there are many conflicting opinions as…

Science Consistency Reviews A Primer for Application

Treesearch

James M. Guldin; David Cawrse; Russell Graham; Miles Hemstrom; Linda Joyce; Steve Kessler; Ranotta McNair; George Peterson; Charles G. Shaw; Peter Stine; Mark Twery; Jeffrey Walter

2003-01-01

Concern over Federal land management decisions has grown in recent years. Public debates over activities on Federal land have been contentious, especially regarding management of national forests. Decisions on the management and use of national forest lands are based on many different considerations and values. Although Federal land managers can make choices concerning...

Short-Term Stability of Psychopathic Traits in Adolescent Offenders

ERIC Educational Resources Information Center

Lee, Zina; Klaver, Jessica R.; Hart, Stephen D.; Moretti, Marlene M.; Douglas, Kevin S.

2009-01-01

There is considerable debate about the assessment of psychopathic traits in adolescence due in part to questions regarding the stability of traits. We investigated the 6-month stability of psychopathic traits in a sample of 83 male adolescent offenders using an augmented protocol for the Psychopathy Checklist: Youth Version and the self-report…

Teaching Community, Praxis, and Courage: A Foundations Pedagogy of Hope and Humanization

ERIC Educational Resources Information Center

Renner, Adam

2009-01-01

America's sense of community is broken down; its sense of connectedness and the collective is "collapsing." That these senses ever existed is a matter for considerable debate. But, as the new millennium gains momentum and neoliberalism seeks expansion, the author argues that a focus on rekindling these concepts of community,…

Understanding Links between Punitive Parenting and Adolescent Adjustment: The Relevance of Context and Reciprocal Associations

ERIC Educational Resources Information Center

Roche, Kathleen M.; Ghazarian, Sharon R.; Little, Todd D.; Leventhal, Tama

2011-01-01

There is considerable debate regarding the extent to which punitive parenting adversely impacts youth well-being. Using an ecological-transactional model of human development, we examined reciprocity and contextual variability in associations between maternal punitive discipline and adolescent adjustment among 1,147 low-income, urban youth…

Towards a Critical Theory of Educational Technology

ERIC Educational Resources Information Center

Okan, Zuhal

2007-01-01

The purpose of this study is to offer a critical consideration of current initiatives, and common sense discourses, forcing educators to adopt and integrate educational technology on a large scale. This study argues that it is time, in the relative absence of a critical debate, to ask questions that should precede a wholesale adoption of…

Distinct Patterns of Grey Matter Abnormality in High-Functioning Autism and Asperger's Syndrome

ERIC Educational Resources Information Center

McAlonan, Grainne M.; Suckling, John; Wong, Naikei; Cheung, Vinci; Lienenkaemper, Nina; Cheung, Charlton; Chua, Siew E.

2008-01-01

Background: Autism exists across a wide spectrum and there is considerable debate as to whether children with Asperger's syndrome, who have normal language milestones, should be considered to comprise a subgroup distinct other from high-functioning children with autism (HFA), who have a history of delayed language development. Magnetic resonance…

The Great Race Debate

ERIC Educational Resources Information Center

Davis, Kimberly

2012-01-01

When the U.S. Supreme Court takes up "Fisher v. Texas" in the fall--its first major consideration of affirmative action policies in higher education since 2003--scholars, legal experts and university administrators say the policies that are the basis of affirmative action in the nation's colleges and universities may be coming to an end. While…

Prosody Signals the Emergence of Intentional Communication in the First Year of Life: Evidence from Catalan-Babbling Infants

ERIC Educational Resources Information Center

Esteve-Gibert, Nuria; Prieto, Pilar

2013-01-01

There is considerable debate about whether early vocalizations mimic the target language and whether prosody signals emergent intentional communication. A longitudinal corpus of four Catalan-babbling infants was analyzed to investigate whether children use different prosodic patterns to distinguish communicative from investigative vocalizations…

The Future of the National Technical Information Service: Issues and Options.

ERIC Educational Resources Information Center

McClure, Charles R.

In recent years there has been considerable debate about the appropriate role, management structure, and activities for the National Technical Information Service (NTIS). This background paper identifies key issues that require attention by Congress and by NTIS itself to increase the effectiveness of NTIS in the collection and dissemination of…

Gender Inequality and Research Performance: Moving beyond Individual-Meritocratic Explanations of Academic Advancement

ERIC Educational Resources Information Center

Nielsen, Mathias Wullum

2016-01-01

Academic debates addressing the persistent gender gap in science reveal considerable contestation of the relevance and extent of the problem. Particular attention has been given to the question of whether women's high attrition rates should be ascribed to the structural and cultural barriers inherent to the academic system or instead…

Landscape assessment of a stable aspen community in southern Utah, USA

Treesearch

Paul C. Rogers; A. Joshua Leffler; Ronald J. Ryel

2010-01-01

Recent reports of rapid die-off of aspen (Populus tremuloides), coupled with vigorous debate over longterm reduction of aspen cover in western North America, has prompted considerable research given the importance of this forest type for economic and non-economic interests. Despite this interest, indicators of aspen conditions are...

Differential Relationships between WISC-IV and WIAT-II Scales: An Evaluation of Potentially Moderating Child Demographics

ERIC Educational Resources Information Center

Konold, Timothy R.; Canivez, Gary L.

2010-01-01

Considerable debate exists regarding the accuracy of intelligence tests with members of different groups. This study investigated differential predictive validity of the "Wechsler Intelligence Scale for Children-Fourth Edition". Participants from the WISC-IV--WIAT-II standardization linking sample (N = 550) ranged in age from 6 through…

Deriving Multidimensional Poverty Indicators: Methodological Issues and an Empirical Analysis for Italy

ERIC Educational Resources Information Center

Coromaldi, Manuela; Zoli, Mariangela

2012-01-01

Theoretical and empirical studies have recently adopted a multidimensional concept of poverty. There is considerable debate about the most appropriate degree of multidimensionality to retain in the analysis. In this work we add to the received literature in two ways. First, we derive indicators of multiple deprivation by applying a particular…

Alcohol Measures and Terms: A Perfect Storm for Chronic Confusion

ERIC Educational Resources Information Center

Glassman, Tavis Jared

2010-01-01

Members in the prevention and treatment fields continue to examine how to most effectively assess and label high volume alcohol consumption. Terms such as "binge" drinking have resulted in considerable controversy and debate. Conventionally the criteria for assessing high-risk drinking includes: five or more drinks for men and four or more drinks…

The Short- and Long-Term Effects of Quality Physical Education

ERIC Educational Resources Information Center

Siegel, Donald

2005-01-01

The short- and long-term effects of quality physical education programs have been a subject of considerable debate by educational administrators and state legislators during the past decade. While physical educators have repeatedly demonstrated the importance of daily moderate and vigorous physical activity on the immediate health and wellbeing of…

Migrant Workers and the Changing Psychological Contract

ERIC Educational Resources Information Center

Morgan, Arthur; Finniear, Jocelyn

2009-01-01

Purpose: The influx of migrant workers in the UK has widespread interest. This group's experience of the British work place has evoked considerable debate ranging from the potential to be exploited through unscrupulous practices to allegations about taking away jobs from British workers. The purpose of this paper is to extend knowledge about the…

Doing the Scut Work of Infant Care: Does Religiousness Encourage Father Involvement?

ERIC Educational Resources Information Center

DeMaris, Alfred; Mahoney, Annette; Pargament, Kenneth I.

2011-01-01

Considerable debate exists regarding whether religiousness promotes or impedes greater father involvement in parenting. Our study addresses this issue using a Midwestern longitudinal data set that tracks the transition to first parenthood for 169 married couples. We focus on performance of the "messier" tasks of infant care. We find little…

A Study of North Carolina Technology Teacher Evaluation Practices and Job Satisfaction

ERIC Educational Resources Information Center

Olah, Dean Anthony

2013-01-01

Defining and measuring teacher effectiveness is one of the most hotly debated topics in public education today. The "No Child Left Behind" Act placed considerable emphasis on high quality teaching standards, making it a focal point of study among educators, administrators, and curriculum developers. Recruitment and retention of high…

Child Labour, Education Policy and Governance in Cambodia

ERIC Educational Resources Information Center

Kim, Chae-Young

2011-01-01

This paper considers how the issue of child labour is located in Cambodian education policy debates and how it is affected by the major constraints surrounding the Cambodian education sector. In particular, it asks why Cambodian policy makers have not sought to address the issue explicitly despite its considerable, and adverse, impact on…

A Descriptive Enquiry into Subject-Verb Concord in English Existential Constructions

ERIC Educational Resources Information Center

Tsuchida, Takehiro

2011-01-01

Subject-verb concord in English existential constructions is often viewed as problematic from both prescriptive and descriptive approaches to grammar and causes considerable confusion among teachers and learners of English as a second language (ESL). This paper aims to disentangle debates over the curious usage of the "there" + plural noun phrase…

The Educational Afterlife of Greater Britain, 1903-1914

ERIC Educational Resources Information Center

Gardner, Philip

2012-01-01

Following its late nineteenth-century emergence as an important element within federalist thinking across the British Empire, the idea of Greater Britain lost much of its political force in the years following the Boer War. The concept however continued to retain considerable residual currency in other fields of Imperial debate, including those…

How Useful Are Indices of Personality Pathology when Assessing Domestic Violence Perpetrators?

ERIC Educational Resources Information Center

Gibbons, Peter; Collins, Marjorie; Reid, Corinne

2011-01-01

There has been considerable debate about profiling personality pathology when assessing and treating male perpetrators of domestic violence (DV). This study used the Millon Clinical Multiaxial Inventory (MCMI-III) to explore the severity and diversity of male perpetrator personality pathology and response bias in a group of DV perpetrators being…

Theoretical Considerations and Standards for the Use of Turnarounds.

ERIC Educational Resources Information Center

Olson, Clark D.

The term "turnaround" has taken a permanent place among the intercollegiate debate jargon. All too often, the first affirmative rebuttalists charge "turnaround" for every plan or response they do not know how to label properly. After so many "false alarms," judges are too weary or aggravated to notice the real thing,…

Childhood and/or Adolescent Sexual Experiences: Predicting Variability in Subsequent Adjustment.

ERIC Educational Resources Information Center

Seidner, Andrea L.; And Others

There is considerable debate regarding the effects of childhood sexual abuse on an individual's subsequent adjustment. To determine which variables are most useful in predicting subsequent adjustment of individuals who were involved in sexual experiences as children or adolescents, 59 female and 17 male undergraduates who reported having had a…

Student, Teacher, Professor: Three Perspectives on Online Education

ERIC Educational Resources Information Center

Pearcy, Mark

2014-01-01

Today, a third of American children regularly use computer tablets, while over 40% use smartphones and 53% regularly use laptops in their home. While this is encouraging there is still considerable debate about the shape and direction technology should take in school, particularly online education making it necessary for educators to change in…

Religion in School, Interreligious Relations and Citizenship: The Case of Pakistan

ERIC Educational Resources Information Center

Leirvik, Oddbjorn

2008-01-01

The article analyses the relation between religion, education and citizenship as reflected in recent research and current debates regarding religion in Pakistani schools. Following a description of the political context, two different views (one Christian, one Muslim) on the current state of affairs are presented. After a consideration of the…

Nonword Repetition and Vocabulary Use in Toddlers

ERIC Educational Resources Information Center

Stokes, Stephanie F.; Moran, Catherine; George, Anjali

2013-01-01

Purpose: There is general consensus that the ability to repeat nonsense words is related to vocabulary size in young children, but there is considerable debate about the nature of the relationship and the mechanisms that underlie it. Research with adults has proposed a shared neural substrate for nonword repetition (NWR) and language production,…

Conflicts of Interest: An Indispensable Element of Education for Sustainable Development

ERIC Educational Resources Information Center

Lundegard, Iann; Wickman, Per-Olof

2007-01-01

A central concept introduced in the Nordic debate on sustainable development is "action competence". The concept has been defined as a competence of learners, i.e. the ability to take into consideration the social factors and human conflict of interest that lies behind environmental questions and sustainable development. The concern of…

Alternative Schedules: What, How, and to What End?

ERIC Educational Resources Information Center

Wasley, Patricia A.

1997-01-01

The principal of a traditional high school in upstate New York asked faculty to reexamine the school schedule. After considerable debate, teachers decided to rotate class time so that no one suffered the afterlunch slump or day's-end rowdiness in a single class. Having gained confidence, a permanent teacher committee has added time blocks and…

Are "Digital Natives" Really Digitally Competent?--A Study on Chinese Teenagers

ERIC Educational Resources Information Center

Li, Yan; Ranieri, Maria

2010-01-01

Literature review has found that despite the considerable attention focused on "digital natives", few studies have carefully investigated the characteristics of this group. The purpose of this study is to contribute to the debate on digital natives by providing a "piece of evidence" on the digital competence status of a group…

Safety of allergen immunotherapy: a review of premedication and dose adjustment.

PubMed

Morris, A Erika; Marshall, Gailen D

2012-03-01

From the first allergen immunotherapy proposed in the early 1900s to the present day, numerous studies have proven the efficacy of allergen immunotherapy for the treatment of allergic rhinitis, allergic conjunctivitis, allergic asthma and stinging insect hypersensitivity. The major risk, however small, with allergen immunotherapy is anaphylaxis. There has been considerable interest and debate regarding risk factors for immunotherapy reactions (local and systemic) and interventions to reduce the occurrence of these reactions. One of these interventions that is especially debated regards dose adjustment for various reasons, but in particular for local reactions. In this review, we discuss the safety of immunotherapy and provide a comprehensive review of the literature regarding immunotherapy schedules and doses.

What is wrong with "ethics for sale"? An analysis of the many issues that complicate the debate about conflicts of interests in bioethics.

PubMed

Sontag, David N

2007-01-01

This article addresses all of the issues involved in the debate about whether or not bioethicists should be paid by private biomedical companies to perform consultations. These issues include the following: differentiation of this role from bioethicists' other roles, an analysis of to whom bioethicists owe a duty, consideration of what bioethicists are "selling," whether bioethicists should be allowed to get paid, when payment becomes problematic, and whether consulting fee arrangements should be regulated. The author often compares bioethicists' relationship to the companies to bioethicists' other relationships, as well as to professional relationships in other fields, such as law and accounting.

Midcingulate Motor Map and Feedback Detection: Converging Data from Humans and Monkeys.

PubMed

Procyk, Emmanuel; Wilson, Charles R E; Stoll, Frederic M; Faraut, Maïlys C M; Petrides, Michael; Amiez, Céline

2016-02-01

The functional and anatomical organization of the cingulate cortex across primate species is the subject of considerable and often confusing debate. The functions attributed to the midcingulate cortex (MCC) embrace, among others, feedback processing, pain, salience, action-reward association, premotor functions, and conflict monitoring. This multiplicity of functional concepts suggests either unresolved separation of functional contributions or integration and convergence. We here provide evidence from recent experiments in humans and from a meta-analysis of monkey data that MCC feedback-related activity is generated in the rostral cingulate premotor area by specific body maps directly related to the modality of feedback. As such, we argue for an embodied mechanism for adaptation and exploration in MCC. We propose arguments and precise tools to resolve the origins of performance monitoring signals in the medial frontal cortex, and to progress on issues regarding homology between human and nonhuman primate cingulate cortex. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Climate, environmental and socio-economic change: weighing up the balance in vector-borne disease transmission

PubMed Central

Parham, Paul E.; Waldock, Joanna; Christophides, George K.; Hemming, Deborah; Agusto, Folashade; Evans, Katherine J.; Fefferman, Nina; Gaff, Holly; Gumel, Abba; LaDeau, Shannon; Lenhart, Suzanne; Mickens, Ronald E.; Naumova, Elena N.; Ostfeld, Richard S.; Ready, Paul D.; Thomas, Matthew B.; Velasco-Hernandez, Jorge; Michael, Edwin

2015-01-01

Arguably one of the most important effects of climate change is the potential impact on human health. While this is likely to take many forms, the implications for future transmission of vector-borne diseases (VBDs), given their ongoing contribution to global disease burden, are both extremely important and highly uncertain. In part, this is owing not only to data limitations and methodological challenges when integrating climate-driven VBD models and climate change projections, but also, perhaps most crucially, to the multitude of epidemiological, ecological and socio-economic factors that drive VBD transmission, and this complexity has generated considerable debate over the past 10–15 years. In this review, we seek to elucidate current knowledge around this topic, identify key themes and uncertainties, evaluate ongoing challenges and open research questions and, crucially, offer some solutions for the field. Although many of these challenges are ubiquitous across multiple VBDs, more specific issues also arise in different vector–pathogen systems. PMID:25688012

An Update to Returning Genetic Research Results to Individuals: Perspectives of the Industry Pharmacogenomics Working Group

PubMed Central

Prucka, Sandra K; Arnold, Lester J; Brandt, John E; Gilardi, Sandra; Harty, Lea C; Hong, Feng; Malia, Joanne; Pulford, David J

2015-01-01

The ease with which genotyping technologies generate tremendous amounts of data on research participants has been well chronicled, a feat that continues to become both faster and cheaper to perform. In parallel to these advances come additional ethical considerations and debates, one of which centers on providing individual research results and incidental findings back to research participants taking part in genetic research efforts. In 2006 the Industry Pharmacogenomics Working Group (I-PWG) offered some ‘Points-to-Consider’ on this topic within the context of the drug development process from those who are affiliated to pharmaceutical companies. Today many of these points remain applicable to the discussion but will be expanded upon in this updated viewpoint from the I-PWG. The exploratory nature of pharmacogenomic work in the pharmaceutical industry is discussed to provide context for why these results typically are not best suited for return. Operational challenges unique to this industry which cause barriers to returning this information are also explained. PMID:24471556

1995 second modulator-klystron workshop: A modulator-klystron workshop for future linear colliders

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-03-01

This second workshop examined the present state of modulator design and attempted an extrapolation for future electron-positron linear colliders. These colliders are currently viewed as multikilometer-long accelerators consisting of a thousand or more RF sources with 500 to 1,000, or more, pulsed power systems. The workshop opened with two introductory talks that presented the current approaches to designing these linear colliders, the anticipated RF sources, and the design constraints for pulse power. The cost of main AC power is a major economic consideration for a future collider, consequently the workshop investigated efficient modulator designs. Techniques that effectively apply the artmore » of power conversion, from the AC mains to the RF output, and specifically, designs that generate output pulses with very fast rise times as compared to the flattop. There were six sessions that involved one or more presentations based on problems specific to the design and production of thousands of modulator-klystron stations, followed by discussion and debate on the material.« less

What every teacher needs to know about clinical reasoning.

PubMed

Eva, Kevin W

2005-01-01

One of the core tasks assigned to clinical teachers is to enable students to sort through a cluster of features presented by a patient and accurately assign a diagnostic label, with the development of an appropriate treatment strategy being the end goal. Over the last 30 years there has been considerable debate within the health sciences education literature regarding the model that best describes how expert clinicians generate diagnostic decisions. The purpose of this essay is to provide a review of the research literature on clinical reasoning for frontline clinical teachers. The strengths and weaknesses of different approaches to clinical reasoning will be examined using one of the core divides between various models (that of analytic (i.e. conscious/controlled) versus non-analytic (i.e. unconscious/automatic) reasoning strategies) as an orienting framework. Recent work suggests that clinical teachers should stress the importance of both forms of reasoning, thereby enabling students to marshal reasoning processes in a flexible and context-specific manner. Specific implications are drawn from this overview for clinical teachers.

NEW EVIDENCE SUPPORTING MEMBERSHIP FOR TW NOR IN LYNGA 6 AND THE CENTAURUS SPIRAL ARM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Majaess, Daniel; Turner, David; Moni Bidin, Christian

2011-11-10

The putative association between the 10{sub .}{sup d}8 classical Cepheid TW Nor and the open cluster Lynga 6 has generated considerable debate in the literature. New JHK{sub s} photometry in tandem with existing radial velocities for Lynga 6 stars implies cluster membership for TW Nor and establishes the variable as a high-weight calibrator for classical Cepheid relations. Fundamental mean parameters determined for Lynga 6 are: d = 1.91 {+-} 0.10 kpc, E(J - H) = 0.38 {+-} 0.02, and log {tau} = 7.9 {+-} 0.1. The Benedict et al./Turner Galactic VI{sub c} Wesenheit function was revised using TW Nor's newmore » parameters: W{sub VI,0} (- 3.37 {+-} 0.08)log P{sub 0} - 2.48 {+-} 0.08. TW Nor/Lynga 6 lie beyond the Sagittarius-Carina spiral arm and occupy the Centaurus arm, along with innumerable young Cepheids and clusters (e.g., VW Cen and VVV CL070).« less

Becoming more oneself? Changes in personality following DBS treatment for psychiatric disorders: Experiences of OCD patients and general considerations

PubMed Central

Rietveld, Erik; Stokhof, Martin; Denys, Damiaan

2017-01-01

Does DBS change a patient’s personality? This is one of the central questions in the debate on the ethics of treatment with Deep Brain Stimulation (DBS). At the moment, however, this important debate is hampered by the fact that there is relatively little data available concerning what patients actually experience following DBS treatment. There are a few qualitative studies with patients with Parkinson’s disease and Primary Dystonia and some case reports, but there has been no qualitative study yet with patients suffering from psychiatric disorders. In this paper, we present the experiences of 18 patients with Obsessive-Compulsive Disorder (OCD) who are undergoing treatment with DBS. We will also discuss the inherent difficulties of how to define and assess changes in personality, in particular for patients with psychiatric disorders. We end with a discussion of the data and how these shed new light on the conceptual debate about how to define personality. PMID:28426824

Complex mediascapes, complex realities: critically engaging with biotechnology debates in Ghana.

PubMed

Rock, Joeva

2018-01-01

The recent increase in research and commercialization of genetically modified (GM) crops in Africa has resulted in considerable and understandable interest from farmers, scholars, and practitioners. However, messy situations are often hard to critically engage in from afar, and the recent article published by Braimah et al. [(2017). Debated agronomy: Public discourse and the future of biotechnology policy in Ghana. Global Bioethics . doi:10.1080/11287462.2016.1261604] presents certain claims that further obfuscate - rather than clarify - an already complex landscape. In this commentary I first seek to clarify particular details of the Ghanaian "GMO" (as GM crops are colloquially called in Ghana) story with particular focus on certain actors and their stances. Next, I highlight some methodological shortcomings of Debated Agronomy and correct certain dubious quotations and claims. Finally, I suggest a more ethnographically and discourse-focused methodology to gain much needed insight into how Ghanaians are actively molding, contesting, and questioning GM discourse, funding, and use.

Patient advocacy and DSM-5.

PubMed

Stein, Dan J; Phillips, Katharine A

2013-05-17

The revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM) provides a useful opportunity to revisit debates about the nature of psychiatric classification. An important debate concerns the involvement of mental health consumers in revisions of the classification. One perspective argues that psychiatric classification is a scientific process undertaken by scientific experts and that including consumers in the revision process is merely pandering to political correctness. A contrasting perspective is that psychiatric classification is a process driven by a range of different values and that the involvement of patients and patient advocates would enhance this process. Here we draw on our experiences with input from the public during the deliberations of the Obsessive Compulsive-Spectrum Disorders subworkgroup of DSM-5, to help make the argument that psychiatric classification does require reasoned debate on a range of different facts and values, and that it is appropriate for scientist experts to review their nosological recommendations in the light of rigorous consideration of patient experience and feedback.

Complex mediascapes, complex realities: critically engaging with biotechnology debates in Ghana

PubMed Central

2018-01-01

ABSTRACT The recent increase in research and commercialization of genetically modified (GM) crops in Africa has resulted in considerable and understandable interest from farmers, scholars, and practitioners. However, messy situations are often hard to critically engage in from afar, and the recent article published by Braimah et al. [(2017). Debated agronomy: Public discourse and the future of biotechnology policy in Ghana. Global Bioethics. doi:10.1080/11287462.2016.1261604] presents certain claims that further obfuscate – rather than clarify – an already complex landscape. In this commentary I first seek to clarify particular details of the Ghanaian “GMO” (as GM crops are colloquially called in Ghana) story with particular focus on certain actors and their stances. Next, I highlight some methodological shortcomings of Debated Agronomy and correct certain dubious quotations and claims. Finally, I suggest a more ethnographically and discourse-focused methodology to gain much needed insight into how Ghanaians are actively molding, contesting, and questioning GM discourse, funding, and use. PMID:29887770

The end of life decisions -- should physicians aid their patients in dying?

PubMed

Sharma, B R

2004-06-01

Decisions pertaining to end of life whether legalized or otherwise, are made in many parts of the world but not reported on account of legal implications. The highly charged debate over voluntary euthanasia and physician assisted suicide was brought into the public arena again when two British doctors confessed to giving lethal doses of drugs to hasten the death of terminally ill patients. Lack of awareness regarding the distinction between different procedures on account of legal status granted to them in some countries is the other area of concern. Some equate withdrawal of life support measures to physician assisted suicide whereas physician assisted suicide is often misinterpreted as euthanasia. Debate among the medical practitioners, law makers and the public taking into consideration the cultural, social and religious ethos will lead to increased awareness, more safeguards and improvement of medical decisions concerning the end of life. International Human Rights Law can provide a consensual basis for such a debate on euthanasia.

Becoming more oneself? Changes in personality following DBS treatment for psychiatric disorders: Experiences of OCD patients and general considerations.

PubMed

de Haan, Sanneke; Rietveld, Erik; Stokhof, Martin; Denys, Damiaan

2017-01-01

Does DBS change a patient's personality? This is one of the central questions in the debate on the ethics of treatment with Deep Brain Stimulation (DBS). At the moment, however, this important debate is hampered by the fact that there is relatively little data available concerning what patients actually experience following DBS treatment. There are a few qualitative studies with patients with Parkinson's disease and Primary Dystonia and some case reports, but there has been no qualitative study yet with patients suffering from psychiatric disorders. In this paper, we present the experiences of 18 patients with Obsessive-Compulsive Disorder (OCD) who are undergoing treatment with DBS. We will also discuss the inherent difficulties of how to define and assess changes in personality, in particular for patients with psychiatric disorders. We end with a discussion of the data and how these shed new light on the conceptual debate about how to define personality.

Gaze stability of observers watching Op Art pictures.

PubMed

Zanker, Johannes M; Doyle, Melanie; Robin, Walker

2003-01-01

It has been the matter of some debate why we can experience vivid dynamic illusions when looking at static pictures composed from simple black and white patterns. The impression of illusory motion is particularly strong when viewing some of the works of 'Op Artists, such as Bridget Riley's painting Fall. Explanations of the illusory motion have ranged from retinal to cortical mechanisms, and an important role has been attributed to eye movements. To assess the possible contribution of eye movements to the illusory-motion percept we studied the strength of the illusion under different viewing conditions, and analysed the gaze stability of observers viewing the Riley painting and control patterns that do not produce the illusion. Whereas the illusion was reduced, but not abolished, when watching the painting through a pinhole, which reduces the effects of accommodation, it was not perceived in flash afterimages, suggesting an important role for eye movements in generating the illusion for this image. Recordings of eye movements revealed an abundance of small involuntary saccades when looking at the Riley pattern, despite the fact that gaze was kept within the dedicated fixation region. The frequency and particular characteristics of these rapid eye movements can vary considerably between different observers, but, although there was a tendency for gaze stability to deteriorate while viewing a Riley painting, there was no significant difference in saccade frequency between the stimulus and control patterns. Theoretical considerations indicate that such small image displacements can generate patterns of motion signals in a motion-detector network, which may serve as a simple and sufficient, but not necessarily exclusive, explanation for the illusion. Why such image displacements lead to perceptual results with a group of Op Art and similar patterns, but remain invisible for other stimuli, is discussed.

Futility: a concept in evolution.

PubMed

Burns, Jeffrey P; Truog, Robert D

2007-12-01

The debate about how to resolve cases in which patients and families demand interventions that clinicians regard as futile has been in evolution over the past 20 years. This debate can be divided into three generations. The first generation was characterized by attempts to define futility in terms of certain clinical criteria. These attempts failed because they proposed limitations to care based on value judgments for which there is no consensus among a significant segment of society. The second generation was a procedural approach that empowered hospitals, through their ethics committees, to decide whether interventions demanded by families were futile. Many hospitals adopted such policies, and some states incorporated this approach into legislation. This approach has also failed because it gives hospitals authority to decide whether or not to accede to demands that the clinicians regard as unreasonable, when any national consensus on what is a "beneficial treatment" remains under intense debate. Absent such a consensus, procedural mechanisms to resolve futility disputes inevitably confront the same insurmountable barriers as attempts to define futility. We therefore predict emergence of a third generation, focused on communication and negotiation at the bedside. We present a paradigm that has proven successful in business and law. In the small number of cases in which even the best efforts at communication and negotiation fail, we suggest that clinicians should find ways to better support each other in providing this care, rather than seeking to override the requests of these patients and families.

A Basic Accounting of Variation in Municipal Solid-Waste Generation at the County Level in Texas, 2006: Groundwork for Applying Metabolic-Rift Theory to Waste Generation

ERIC Educational Resources Information Center

Clement, Matthew Thomas

2009-01-01

Environmental social scientists debate whether or not modern development reduces society's impact on the biosphere. The empirical research informing the discussion has not yet adequately examined the social determinants of municipal solid-waste (MSW) generation, an increasingly relevant issue, both ecologically and sociologically. A primary…

Student Understanding of Climate Change: Influences of College Major and Environmental Group Membership on Undergraduate Knowledge and Mental Models

ERIC Educational Resources Information Center

Huxster, Joanna

2013-01-01

A consensus has been reached within the scientific community concerning the occurrence of climate change and its anthropogenic causes. Outside of this community, however, there continues to be considerable debate and confusion surrounding the topic. The government mitigation strategies and political leadership needed for this issue will require…

A Quasi-Experimental Analysis of Fraternity or Sorority Membership and College Student Success

ERIC Educational Resources Information Center

Bowman, Nicholas A.; Holmes, Joshua M.

2017-01-01

Despite considerable debate about the effects of fraternities and sororities on college campuses, the extent to which these organizations promote or detract from student success is unclear. Therefore, we used propensity score analyses to examine the link between membership in a social fraternity or sorority and several student success outcomes.…

Considerate, Convivial and Capacious? Finding a Language to Capture Ethos in "Creative" Schools

ERIC Educational Resources Information Center

Bragg, Sara; Manchester, Helen

2017-01-01

Concepts of school "ethos" or "culture" have been widely debated in education since the 1980s. This is partly as a consequence of marketisation, partly because ethos has been identified as a low-cost route to school improvement. Corporate, authoritarian, and most recently "military" models of ethos have been widely…

Visual Impairments in People with Severe and Profound Multiple Disabilities: An Inventory of Visual Functioning

ERIC Educational Resources Information Center

van den Broek, Ellen G. C.; Janssen, C. G. C.; van Ramshorst, T.; Deen, L.

2006-01-01

Background: The prevalence of visual impairments in people with severe and profound multiple disabilities (SPMD) is the subject of considerable debate and is difficult to assess. Methods: In a typical Dutch care organization, all clients with SPMD (n = 76) participated in the study and specific instruments adapted to these clients (requiring a…

Continuing Appropriations Resolution, 2012

THOMAS, 112th Congress

Rep. Rogers, Harold [R-KY-5

2011-09-14

House - 09/15/2011 Rules Committee Resolution H. Res. 399 Reported to House. Rule provides for consideration of H.J. Res. 79 with 1 hour of general debate. Previous question shall be considered as ordered without intervening motions except motion to recommit with or without... (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

A Transnational Approach to "ReOrient" Asian Studies to Global Studies

ERIC Educational Resources Information Center

Marinelli, Maurizio

2007-01-01

This article is written in line with the debate on internationalisation in higher education, especially taking into consideration the connections between the rise of East Asia and the need to internationalise the universities in the West. The author focuses specifically on his professional experience as a member of the Expanding East Asian Studies…

Private Schools as Battlefields: Contested Visions of Learning and Livelihood in Nepal

ERIC Educational Resources Information Center

Caddell, Martha

2006-01-01

Current policy and programme considerations of the role of the private sector in the promotion of schooling reform and the achievement of Education For All encompass a somewhat narrow arena of debate. Discussion of the relative merits of private / state schools remain based on measurable, yet partial, markers of efficiency and effectiveness.…

Social Media, Professionalism and Higher Education: A Sociomaterial Consideration

ERIC Educational Resources Information Center

Fenwick, Tara

2016-01-01

Within debates about student professionalism and how to develop it in higher education (HE), increasing focus has turned to students' uses of social media. While social media skills are promoted by some HE educators, most emphasis is still given to perceived hazards and abuses of social media in practice. These are typically framed as a matter of…

A Simple Experiment to Demonstrate the Effects of Greenhouse Gases

ERIC Educational Resources Information Center

Keating, C. F.

2007-01-01

The role of greenhouse gases in our atmosphere is the subject of considerable discussion and debate. Global warming is well-documented, as is the continually increasing amount of greenhouse gases that human activity puts in the air. Is there a relationship between the two? The simple experiment described in this paper provides a good demonstration…

Without You None of This Would Have Happened: A Consideration of University Teaching

ERIC Educational Resources Information Center

Esteban Bara, Francisco

2014-01-01

Teaching in university has been widely debated in the past few years. However, this issue should not be limited solely to psychological and pedagogical matters. This paper examines university teaching in terms of its relational and human dimension which, as we would expect, also has an important impact on learning and student development. The…

Who Has Rights to What? Inclusion in Australian Early Childhood Programs

ERIC Educational Resources Information Center

Petriwskyj, Anne

2010-01-01

In early childhood settings prior to school and in the early years of primary school, debate continues over the meaning of inclusion and its scope in terms of the groups under consideration. The genealogies of early childhood education and care, early primary school, special education and cultural education were examined to identify recurring and…

Attitudes of Turkish EFL Student Teachers towards Technology Use

ERIC Educational Resources Information Center

Baz, Esra Harmandaoglu

2016-01-01

The hot debate of integrating technology into instruction has captured the interest of the world in the context of 21st century education. A considerable amount of effort has been presented in order to incorporate technology into education. In this respect, attitudes have been considered as a good indicator of the tendency to implement technology…

Privatising Public Schooling in Post-Apartheid South Africa: Equity Considerations

ERIC Educational Resources Information Center

Motala, Shireen

2009-01-01

Through an analysis of quantitative and qualitative data on school funding in South Africa, this paper aims to analyse the user fee policy option in public schooling in South Africa. Debate is ongoing about the role of private input into public schooling and whether this practice affects access (and the constitutional right) to basic education,…

Problems in the Pipeline: Stereotype Threat and Women's Achievement in High-Level Math Courses

ERIC Educational Resources Information Center

Good, Catherine; Aronson, Joshua; Harder, Jayne Ann

2008-01-01

It is well established that negative stereotypes can undermine women's performance on mathematics tests. Despite considerable laboratory evidence for the role of "stereotype threat" in girls' and women's math test performance, the relevance of such findings for the "real world" gender test-score gap remains unclear and debates about causes focus…

High Possibility Classrooms as a Pedagogical Framework for Technology Integration in Classrooms: An Inquiry in Two Australian Secondary Schools

ERIC Educational Resources Information Center

Hunter, Jane

2017-01-01

Understanding how well teachers integrate digital technology in learning is the subject of considerable debate in education. High Possibility Classrooms (HPC) is a pedagogical framework drawn from research on exemplary teachers' knowledge of technology integration in Australian school classrooms. The framework is being used to support teachers who…

Recovery in Context: Bereavement, Culture, and the Transformation of the Therapeutic Self

ERIC Educational Resources Information Center

Paletti, Robin

2008-01-01

The concept of recovery is integral to the work of bereavement professionals, though there remains considerable debate as to the precise definition and applicability of the term. A number of factors have contributed to the controversy; competing bereavement models, for instance, have given rise to fundamental differences in the way that recovery…

Literacy in a 'Broad and Balanced' Primary School Curriculum: The Potential of a Disciplinary Approach in Irish Classrooms

ERIC Educational Resources Information Center

Burke, Patrick; Welsch, Jodi G.

2018-01-01

The prominence afforded to literacy in the Irish Primary School Curriculum has received considerable attention in recent years, spurred by Programme for International Student Assessment (PISA) rankings, governmental priorities, public commentary and academic debate. At times, this discourse has presented literacy as a separate and distinct entity…

Educational Inclusion in England: Origins, Perspectives and Current Directions

ERIC Educational Resources Information Center

Lauchlan, Fraser; Greig, Susan

2015-01-01

In this paper we examine different aspects of the inclusion debate, including how it has been shaped by the political context in England over the past 30 years. We then give consideration to the key argument that has dominated the inclusion agenda over the last decade: should effective inclusion be considered only as placement in mainstream school…

Gender Risks and Education: The Particular Classroom Challenges for Urban Low-Income African American Boys

ERIC Educational Resources Information Center

Thomas, Duane E.; Stevenson, Howard

2009-01-01

A fundamental consideration in discourses on risk and schooling for primary and secondary school-age students focuses on gender inequalities in the classroom. Gender equity in education debates have raged for several decades and so remain an enduring concern of educators and researchers across the nation. However, educational research often…

Orbitals in Chemical Education. An Analysis through Their Graphical Representations

ERIC Educational Resources Information Center

Barradas-Solas, Francisco; Gomez, Pedro J. Sanchez

2014-01-01

Students' understanding of the orbital concept has been subject to considerable research and debate and often found at variance with a quantum mechanical ideal. Could it be the case that orbitals as actually used by practising chemists in teaching and research also differ from that ideal? Our experience shows that this might often be the case.…

ICT and Educational (Dis)advantage: Families, Computers and Contemporary Social and Educational Inequalities

ERIC Educational Resources Information Center

Angus, Lawrence; Snyder, Ilana; Sutherland-Smith, Wendy

2004-01-01

Because access to new technologies is unequally distributed, there has been considerable debate about the growing gap between the so-called information-rich and information-poor. Such concerns have led to high-profile information technology policy initiatives in many countries. In Australia, in an attempt to 'redress the balance between the…

The Academic Achievement of Elite Athletes at an Australian University: Debunking the Dumb Jock Syndrome

ERIC Educational Resources Information Center

Georgakis, Steve; Wilson, Rachel; Ferguson, Jamaya

2014-01-01

Elite athletes and their academic achievement in higher education have long been subject to considerable debate within North American scholarship. This interest proliferated especially after the release of the Knight Report (2001), which, amongst other findings, revealed a clear negative link between elite athletes and their academic achievement.…

Arab Education Going Medieval: Sanitizing Western Representation in Arab Schools

ERIC Educational Resources Information Center

Labidi, Imed

2010-01-01

In the aftermath of the events of September 11, 2000, debate about Arab education as the new apparatus for religious fanaticism used by Arab extremist groups to entice hate and violence against the West took prominence in Western discourse. Considerable ink was spilled confusing hostile narratives in Arab curricula and the metaphors of identity…

Growing into What? The (Un-)Disciplined Socialisation of Early Stage Researchers in Transdisciplinary Research

ERIC Educational Resources Information Center

Felt, Ulrike; Igelsbock, Judith; Schikowitz, Andrea; Volker, Thomas

2013-01-01

Over past decades we have witnessed considerable debate questioning the capacity of contemporary research to address the challenges posed by complex societal developments. As a consequence the need for rethinking cultures and practices of knowledge production has moved high on the policy agenda. In this context transdisciplinarity has become one…

A Unified Framework for Bounded and Unbounded Numerical Estimation

ERIC Educational Resources Information Center

Kim, Dan; Opfer, John E.

2017-01-01

Representations of numerical value have been assessed by using bounded (e.g., 0-1,000) and unbounded (e.g., 0-?) number-line tasks, with considerable debate regarding whether 1 or both tasks elicit unique cognitive strategies (e.g., addition or subtraction) and require unique cognitive models. To test this, we examined how well a mixed log-linear…

Sediment transport and soil disturbance after postfire logging.

Treesearch

James D. McIver

2003-01-01

Recently there has been considerable debate on the practice of postfire logging, in which burned forests are entered soon after fire to recover commercially valuable trees. Proponents of the practice argue that postfire logging is part of a 'restoration package' that can be used to control erosion (e.g., contour logging) and can help to mitigate costs of...

Artificial gravity reveals that economy of action determines the stability of sensorimotor coordination.

PubMed

Carson, Richard G; Oytam, Yalchin; Riek, Stephan

2009-01-01

When we move along in time with a piece of music, we synchronise the downward phase of our gesture with the beat. While it is easy to demonstrate this tendency, there is considerable debate as to its neural origins. It may have a structural basis, whereby the gravitational field acts as an orientation reference that biases the formulation of motor commands. Alternatively, it may be functional, and related to the economy with which motion assisted by gravity can be generated by the motor system. We used a robotic system to generate a mathematical model of the gravitational forces acting upon the hand, and then to reverse the effect of gravity, and invert the weight of the limb. In these circumstances, patterns of coordination in which the upward phase of rhythmic hand movements coincided with the beat of a metronome were more stable than those in which downward movements were made on the beat. When a normal gravitational force was present, movements made down-on-the-beat were more stable than those made up-on-the-beat. The ubiquitous tendency to make a downward movement on a musical beat arises not from the perception of gravity, but as a result of the economy of action that derives from its exploitation.

Novel bone metabolism-associated hormones: the importance of the pre-analytical phase for understanding their physiological roles.

PubMed

Lombardi, Giovanni; Barbaro, Mosè; Locatelli, Massimo; Banfi, Giuseppe

2017-06-01

The endocrine function of bone is now a recognized feature of this tissue. Bone-derived hormones that modulate whole-body homeostasis, are being discovered as for the effects on bone of novel and classic hormones produced by other tissues become known. Often, however, the data regarding these last generation bone-derived or bone-targeting hormones do not give about a clear picture of their physiological roles or concentration ranges. A certain degree of uncertainty could stem from differences in the pre-analytical management of biological samples. The pre-analytical phase comprises a series of decisions and actions (i.e., choice of sample matrix, methods of collection, transportation, treatment and storage) preceding analysis. Errors arising in this phase will inevitably be carried over to the analytical phase where they can reduce the measurement accuracy, ultimately, leading discrepant results. While the pre-analytical phase is all important, in routine laboratory medicine, it is often not given due consideration in research and clinical trials. This is particularly true for novel molecules, such as the hormones regulating the endocrine function of bone. In this review we discuss the importance of the pre-analytical variables affecting the measurement of last generation bone-associated hormones and describe their, often debated and rarely clear physiological roles.

The fact of uncertainty, the uncertainty of facts and the cultural resonance of doubt.

PubMed

Oreskes, Naomi

2015-11-28

Sixty years after industry executives first decided to fight the facts of tobacco, the exploitation of doubt and uncertainty as a defensive tactic has spread to a diverse set of industries and issues with an interest in challenging scientific evidence. However, one can find examples of doubt-mongering before tobacco. One involves the early history of electricity generation in the USA. In the 1920s, the American National Electric Light Association ran a major propaganda campaign against public sector electricity generation, focused on the insistence that privately generated electricity was cheaper and that public power generation was socialistic and therefore un-American. This campaign included advertisements, editorials (generally ghost-written), the rewriting of textbooks and the development of high school and college curricula designed to cast doubt on the cost-effectiveness of public electricity generation and extol the virtues of laissez-faire capitalism. It worked in large part by finding, cultivating and paying experts to endorse the industry's claims in the mass media and the public debate, and to legitimatize the alterations to textbooks and curricula. The similarities between the electric industry strategy and the defence of tobacco, lead paint and fossil fuels suggests that these strategies work for reasons that are not specific to the particular technical claims under consideration. This paper argues that a reason for the cultural persistence of doubt is what we may label the 'fact of uncertainty'. Uncertainty is intrinsic to science, and this creates vulnerabilities that interested parties may, and commonly do, exploit, both by attempting to challenge the specific conclusions of technical experts and by implying that those conclusions threaten other social values. © 2015 The Author(s).

An Integrative Account of Constraints on Cross-Situational Learning

PubMed Central

Yurovsky, Daniel; Frank, Michael C.

2015-01-01

Word-object co-occurrence statistics are a powerful information source for vocabulary learning, but there is considerable debate about how learners actually use them. While some theories hold that learners accumulate graded, statistical evidence about multiple referents for each word, others suggest that they track only a single candidate referent. In two large-scale experiments, we show that neither account is sufficient: Cross-situational learning involves elements of both. Further, the empirical data are captured by a computational model that formalizes how memory and attention interact with co-occurrence tracking. Together, the data and model unify opposing positions in a complex debate and underscore the value of understanding the interaction between computational and algorithmic levels of explanation. PMID:26302052

Reprioritizing Research Activity for the Post-Antibiotic Era: Ethical, Legal, and Social Considerations.

PubMed

Hey, Spencer Phillips; Kesselheim, Aaron S

2017-03-01

Many hold that the so-called golden era of antibiotic discovery has passed, leaving only a limited clinical pipeline for new antibiotics. A logical conclusion of such arguments is that we need to reform the current system of antibiotic drug research-including clinical trials and regulatory requirements-to spur activity in discovery and development. The United States Congress in the past few years has debated a number of bills to address this crisis, including the 2012 Generating Antibiotic Incentives Now Act and the 2016 21st Century Cures Act. Experts have also sought to advance antibiotic development by encouraging greater use of trials with noninferiority hypotheses, which are thought to be easier to conduct. The goal underlying these proposals is to stave off the post-antibiotic era by expanding the pharmaceutical armamentarium as quickly as possible. But although new antibiotic agents are necessary to combat the long-term threat of drug-resistant disease, we argue that these research policies, which effectively lower the bar for antibiotic approval, are ethically problematic. Rather, given broader public health considerations related to the full lifecycle of antibiotic use-including development of resistance-we should reject an overly permissive approach to new antibiotic approval and instead set the bar for regulatory approval at a point that will naturally direct research resources toward the most transformative chemical or social interventions. © 2017 The Hastings Center.

Responsible innovation in human germline gene editing: Background document to the recommendations of ESHG and ESHRE.

PubMed

De Wert, Guido; Heindryckx, Björn; Pennings, Guido; Clarke, Angus; Eichenlaub-Ritter, Ursula; van El, Carla G; Forzano, Francesca; Goddijn, Mariëtte; Howard, Heidi C; Radojkovic, Dragica; Rial-Sebbag, Emmanuelle; Dondorp, Wybo; Tarlatzis, Basil C; Cornel, Martina C

2018-04-01

Technological developments in gene editing raise high expectations for clinical applications, including editing of the germline. The European Society of Human Reproduction and Embryology (ESHRE) and the European Society of Human Genetics (ESHG) together developed a Background document and Recommendations to inform and stimulate ongoing societal debates. This document provides the background to the Recommendations. Germline gene editing is currently not allowed in many countries. This makes clinical applications in these countries impossible now, even if germline gene editing would become safe and effective. What were the arguments behind this legislation, and are they still convincing? If a technique could help to avoid serious genetic disorders, in a safe and effective way, would this be a reason to reconsider earlier standpoints? This Background document summarizes the scientific developments and expectations regarding germline gene editing, legal regulations at the European level, and ethics for three different settings (basic research, preclinical research and clinical applications). In ethical terms, we argue that the deontological objections (e.g., gene editing goes against nature) do not seem convincing while consequentialist objections (e.g., safety for the children thus conceived and following generations) require research, not all of which is allowed in the current legal situation in European countries. Development of this Background document and Recommendations reflects the responsibility to help society understand and debate the full range of possible implications of the new technologies, and to contribute to regulations that are adapted to the dynamics of the field while taking account of ethical considerations and societal concerns.

Fresh embryo donation for human embryonic stem cell (hESC) research: the experiences and values of IVF couples asked to be embryo donors

PubMed Central

Haimes, E.; Taylor, K.

2009-01-01

BACKGROUND This article reports on an investigation of the views of IVF couples asked to donate fresh embryos for research and contributes to the debates on: the acceptability of human embryonic stem cell (hESC) research, the moral status of the human embryo and embryo donation for research. METHODS A hypothesis-generating design was followed. All IVF couples in one UK clinic who were asked to donate embryos in 1 year were contacted 6 weeks after their pregnancy result. Forty four in-depth interviews were conducted. RESULTS Interviewees were preoccupied with IVF treatment and the request to donate was a secondary consideration. They used a complex and dynamic system of embryo classification. Initially, all embryos were important but then their focus shifted to those that had most potential to produce a baby. At that point, ‘other’ embryos were less important though they later realise that they did not know what happened to them. Guessing that these embryos went to research, interviewees preferred not to contemplate what that might entail. The embryos that caused interviewees most concern were good quality embryos that might have produced a baby but went to research instead. ‘The’ embryo, the morally laden, but abstract, entity, did not play a central role in their decision-making. CONCLUSIONS This study, despite missing those who refuse to donate embryos, suggests that debates on embryo donation for hESC research should include the views of embryo donors and should consider the social, as well as the moral, status of the human embryo. PMID:19502616

Public health, science, and policy debate: being right is not enough.

PubMed

Camargo, Kenneth; Grant, Roy

2015-02-01

Public health is usually enacted through public policies, necessitating that the public engage in debates that, ideally, are grounded in solid scientific findings. Mistrust in science, however, has compromised the possibility of deriving sound policy from such debates, partially owing to justified concerns regarding undue interference and even outright manipulation by commercial interests. This situation has generated problematic impasses, one of which is the emergence of an anti-vaccination movement that is already affecting public health, with a resurgence in the United States of preventable diseases thought to have been eradicated. Drawing on British sociologist Harry Collins' work on expertise, we propose a theoretical framework in which the paralyzing, undue public distrust of science can be analyzed and, it is hoped, overcome.

Reframing Gerontological Thought and Practice: The Case of Grandmothers with Daughters in Prison.

ERIC Educational Resources Information Center

Dressel, Paula L.; Barnhill, Sandra K.

1994-01-01

Uses data from grandmothers with daughters in prison to illustrate need to transcend "either-or" arguments around age as master status; highlight absence of middle generation in growing number of families; and question anti-family premises of generational equity debate. Concludes with recommendations for how researchers and advocates could enhance…

The "Digital Natives" Debate: A Critical Review of the Evidence

ERIC Educational Resources Information Center

Bennett, Sue; Maton, Karl; Kervin, Lisa

2008-01-01

The idea that a new generation of students is entering the education system has excited recent attention among educators and education commentators. Termed "digital natives" or the "Net generation", these young people are said to have been immersed in technology all their lives, imbuing them with sophisticated technical skills and learning…

Social Networking in Schools: Benefits and Risks; Review of the Research; Policy Considerations; and Current Practices. Information Capsule. Volume 1109

ERIC Educational Resources Information Center

Blazer, Christie

2012-01-01

The role that social media should play in education is being hotly debated in school districts across the country. The adoption of social networking for educational purposes lags behind the public's general usage because educators fear that students will be exposed to inappropriate online content, unwanted adult interactions, and bullying from…

Edge Effects and Ecological Traps: Effects on Shrubland Birds in Missouri

Treesearch

April A. Woodward; Alix D. Fink; Frank R. Thompson III

2001-01-01

The effect of habitat edge on avian nesting success has been the focus of considerable debate. We studied relationships between habitat edges, locations of nests, and predation. We tested the ecological trap hypothesis for 5 shrubland bird species in the Missouri Ozarks. We compared habitat selection and daily nest predation rates among 3 distance-to-edge categories....

Understanding the Role of Culture in Developing Inclusive Schools: A Case Study from Cyprus

ERIC Educational Resources Information Center

Angelides, Panayiotis; Antoniou, Eleni

2012-01-01

Over the last few years, there has been considerable debate regarding the ways in which the different educational systems in the world should develop more inclusive practices in their schools. An important aspect of this discussion revolves around the question of what schools can do to become more inclusive in terms of maximizing the participation…

Parental Choice? A Critical Reconsideration of Choice and the Debate about Choice. Critical Constructions: Studies on Education and Society

ERIC Educational Resources Information Center

Thomas, P. L.

2010-01-01

Education has rarely been absent from local and national public discourse. Throughout the history of modern education spanning more than a century, individuals have as a culture lamented the failures of public schooling, often making such claims based on assumptions instead of any nuanced consideration of the many influences on teaching and…

Examining the Factor Structure and Hierarchical Nature of the Quality of Life Construct

ERIC Educational Resources Information Center

Wang, Mian; Schalock, Robert L.; Verdugo, Miguel A.; Jenaro, Christina

2010-01-01

There is considerable debate in the area of individual quality of life research regarding the factor structure and hierarchical nature of the quality of life construct. Our purpose in this study was to test via structural equation modeling an a priori quality of life model consisting of eight first-order factors and one second-order factor. Data…

Preparing College Students for Real-World 2.0: Towards a Recipe for the "Secret Sauce"

ERIC Educational Resources Information Center

Gordon, Steven; Gayeski, Diane

2013-01-01

In light of considerable debate centering on the value of higher education and its effect on student preparation for the world of work, this article describes new methods employed in teaching an introductory professional course and the outcomes of its initial offerings. This case study supports research indicating that problem-based learning is an…

Demographically idiosyncratic responses to climate change and rapid Pleistocene diversification of the walnut genus Juglans (Juglandaceae) revealed by whole-genome sequences

Treesearch

Wei-Ning Bai; Peng-Cheng Yan; Bo-Wen Zhang; Keith E. Woeste; Kui Lin; Da-Yong Zhang

2018-01-01

Whether species demography and diversification are driven primarily by extrinsic environmental changes such as climatic oscillations in the Quaternary or by intrinsic biological interactions like coevolution between antagonists is a matter of active debate. In fact, their relative importance can be assessed by tracking past population fluctuations over considerable...

Reading the "International" through Postcolonial Theory: A Case Study of the Adoption of the International Baccalaureate at a School in Lebanon

ERIC Educational Resources Information Center

Azzi, Iman

2018-01-01

Considerable debate has revolved around the question of what constitutes an international school, focusing on attributes such as number of nations represented by the student body, stated curricular goals, and school culture or mission. Less attention has been paid to how "international" is lived within these schools. This article…

Peer Assessment in MOOCs: The Relationship between Peer Reviewers' Ability and Authors' Essay Performance

ERIC Educational Resources Information Center

Huisman, Bart; Admiraal, Wilfried; Pilli, Olga; van de Ven, Maarten; Saab, Nadira

2018-01-01

In a relatively short period of time, massive open online courses (MOOCs) have become a considerable topic of research and debate, and the number of available MOOCs is rapidly growing. Along with issues of formal recognition and accreditation, this growth in the number of MOOCs being developed increases the relevance of assessment quality. Within…

Assessment Policy and Practice in Higher Education: Purpose, Standards and Equity

ERIC Educational Resources Information Center

Leathwood, Carole

2005-01-01

This paper places a discussion of assessment in higher education (HE) in the UK within the wider policy context. It argues for a critical sociological analysis to consider some of the issues, themes and debates in relation to assessment in HE at this time. Recent trends in assessment policy and practice are discussed, alongside a consideration of…

Discursive Dancing: Traditionalism and Social Realism in the 2013 English History Curriculum Wars

ERIC Educational Resources Information Center

Smith, Joseph

2017-01-01

This paper is an exploration of the debates surrounding the publication of a new National Curriculum for history in England. The draft curriculum was published in February 2013 and was withdrawn just 6 months later in the face of considerable opposition. This paper offers a tentative explanation for this example of a rare phenomenon: effective…

A Sense of Deja Vu across the Tasman? What Australians Might Learn from the New Zealand Experience with the Te Kotahitanga Professional Development Programme

ERIC Educational Resources Information Center

Openshaw, Roger

2007-01-01

Throughout Australasia, indigenous educational issues remain a subject of considerable debate. In New Zealand, Maori underachievement in education has long been a matter of widespread concern. Currently the most highly visible professional development programme now operating in New Zealand mainstream secondary schools, Te Kotahitanga claims to…

The Nature of an Object-Oriented Program: How Do Practitioners Understand the Nature of What They Are Creating?

ERIC Educational Resources Information Center

Thompson, Errol; Kinshuk

2011-01-01

Object-oriented programming is seen as a difficult skill to master. There is considerable debate about the most appropriate way to introduce novice programmers to object-oriented concepts. Is it possible to uncover what the critical aspects or features are that enhance the learning of object-oriented programming? Practitioners have differing…

The Economics of Timber Supply: An Analytical Synthesis of Modeling Approaches

Treesearch

David N. Wear; Peter J. Parks

1994-01-01

The joint supply of timber and other services from forest environments plays a central role in most forest land debates. This paper defines a general conceptual model of timber supply that provides the context for discussing both individual harvest choice and aggregate supply models. While the structure and breadth of these models has developed considerably over the...

Soil disturbance and hill-slope sediment transport after logging of a severely burned site in northeastern Oregon.

Treesearch

James D. McIver; R. McNeil

2006-01-01

Despite considerable public debate in recent years on the practice of postfire logging, few studies have directly evaluated its effects. Soil disturbance and hill-slope sediment transport were measured after a postfire logging operation conducted two years after the 1996 Summit Wildfire (Malheur National Forest), in northeastern Oregon. The wildfire was relatively...

An Interdisciplinary Approach to Environmental and Sustainability Education: Developing Geography Students' Understandings of Sustainable Development Using Poetry

ERIC Educational Resources Information Center

Walshe, Nicola

2017-01-01

Education for sustainable development (ESD) persists as an important concept within international policy and yet, despite considerable debate, there remains a lack of consensus as to a pedagogy for ESD in schools. This paper presents findings from a study investigating how an interdisciplinary approach to ESD in England developed one class of 16-…

Using E-Cigarettes in the Home to Reduce Smoking and Secondhand Smoke: Disadvantaged Parents' Accounts

ERIC Educational Resources Information Center

Rowa-Dewar, Neneh; Rooke, Catriona; Amos, Amanda

2017-01-01

Electronic cigarettes (e-cigarettes) are subject to considerable public health debate. Most public health experts agree that for smokers who find it particularly challenging to quit, e-cigarettes may reduce harm. E-cigarette use in the home may also reduce children's secondhand smoke (SHS) exposure, although e-cigarette vapour may pose risks. This…

Does MTV Really Do a Good Job of Evaluating Professors? An Empirical Test of the Internet Site Ratemyprofessors.com

ERIC Educational Resources Information Center

Murray, Keith B.; Zdravkovic, Srdan

2016-01-01

Considerable debate continues regarding the efficacy of the website RateMyProfessors.com (RMP). To date, however, virtually no direct, experimental research has been reported which directly bears on questions relating to sampling adequacy or item adequacy in producing what favorable correlations have been reported. The authors compare the data…

The Conditional Effect of Parental Drug Use on Parental Attachment and Adolescent Drug Use: Social Control and Social Development Model Perspectives

ERIC Educational Resources Information Center

Drapela, Laurie A.; Mosher, Clayton

2007-01-01

The effect of parental deviance on adolescent deviance has been a source of considerable debate in the criminological literature. Classic theoretical explanations of the relationships between parental and adolescent deviance posit additive effects of parental deviance on youth behavior. Proponents of the Social Development Model have hypothesized…

[PSMA-PET/CT has to be performed in every patient with biochemical recurrence following radical prostatectomy for early tumor detection].

PubMed

Kotzerke, Jörg; Böhmer, Dirk; Schlomm, Thorsten; Maurer, Thomas; Beer, Ambros J; Schmidberger, Heinz

2018-06-01

The debate refers the known evidence for PSMA-PET/CT in biochemical recurrence of prostate cancer and consider carefully interdisciplinary in which situation which patient needs imaging to choose the adequate therapeutic option. General aspects for the care of cancer patients are taken into consideration. Schattauer GmbH.

Fostering Success or Stratification? A Macroapproach to Understanding "Success" in the Community College Context

ERIC Educational Resources Information Center

Ireland, S. Mei-Yen

2015-01-01

The topic of student success is a central focus for community college educators and researchers, yet little consideration is given to the long-term success that community college students may or may not be attaining. What role (if any) do concerns about social stratification have in the debate over student success? Exploring the ways in which…

"My Key to the Men's Room": Mentor and Protege Relationships in Business and Professional Organizations. An Overview.

ERIC Educational Resources Information Center

Lawrence, Kathleen A.

A mentor is a close, trusted, and experienced counselor or guide who trains, disciplines, and assumes a great deal of responsibility in assisting the protege. Considerable debate exists in organizational research as to the value and benefit of mentors, and only recently have some businesses recognized mentors as important to the shaping of new…

"Heating up" or "Cooling up" the Brain? MEG Evidence that Phrasal Verbs Are Lexical Units

ERIC Educational Resources Information Center

Cappelle, Bert; Shtyrov, Yury; Pulvermuller, Friedemann

2010-01-01

There is a considerable linguistic debate on whether phrasal verbs (e.g., "turn up," "break down") are processed as two separate words connected by a syntactic rule or whether they form a single lexical unit. Moreover, views differ on whether meaning (transparency vs. opacity) plays a role in determining their syntactically-connected or lexical…

Exploring early public responses to geoengineering.

PubMed

Pidgeon, Nick; Corner, Adam; Parkhill, Karen; Spence, Alexa; Butler, Catherine; Poortinga, Wouter

2012-09-13

Proposals for geoengineering the Earth's climate are prime examples of emerging or 'upstream' technologies, because many aspects of their effectiveness, cost and risks are yet to be researched, and in many cases are highly uncertain. This paper contributes to the emerging debate about the social acceptability of geoengineering technologies by presenting preliminary evidence on public responses to geoengineering from two of the very first UK studies of public perceptions and responses. The discussion draws upon two datasets: qualitative data (from an interview study conducted in 42 households in 2009), and quantitative data (from a subsequent nationwide survey (n=1822) of British public opinion). Unsurprisingly, baseline awareness of geoengineering was extremely low in both cases. The data from the survey indicate that, when briefly explained to people, carbon dioxide removal approaches were preferred to solar radiation management, while significant positive correlations were also found between concern about climate change and support for different geoengineering approaches. We discuss some of the wider considerations that are likely to shape public perceptions of geoengineering as it enters the media and public sphere, and conclude that, aside from technical considerations, public perceptions are likely to prove a key element influencing the debate over questions of the acceptability of geoengineering proposals.

Woodpeckers and Diamonds: Some Aspects of Evolutionary Convergence in Astrobiology.

PubMed

Ćirković, Milan M

2018-05-01

Jared Diamond's argument against extraterrestrial intelligence from evolutionary contingency is subjected to critical scrutiny. As with the earlier arguments of George Gaylord Simpson, it contains critical loopholes that lead to its unraveling. From the point of view of the contemporary debates about biological evolution, perhaps the most contentious aspect of such arguments is their atemporal and gradualist usage of the space of all possible biological forms (morphospace). Such usage enables the translation of the adaptive value of a trait into the probability of its evolving. This procedure, it is argued, is dangerously misleading. Contra Diamond, there are reasons to believe that convergence not only plays an important role in the history of life, but also profoundly improves the prospects for search for extraterrestrial intelligence success. Some further considerations about the role of observation selection effects and our scaling of complexity in the great debate about contingency and convergence are given. Taken together, these considerations militate against the pessimism of Diamond's conclusion, and suggest that the search for traces and manifestations of extraterrestrial intelligences is far from forlorn. Key Words: Astrobiology-Evolution-Contingency-Convergence-Complex life-SETI-Major evolutionary transitions-Selection effects-Jared Diamond. Astrobiology 18, 491-502.

Designing for students' science learning using argumentation and classroom debate

NASA Astrophysics Data System (ADS)

Bell, Philip Laverne

1998-12-01

This research investigates how to design and introduce an educational innovation into a classroom setting to support learning. The research yields cognitive design principles for instruction involving scientific argumentation and debate. Specifically, eighth-grade students used a computer learning environment to construct scientific arguments and to participate in a classroom debate. The instruction was designed to help students integrate their science understanding by debating: How far does light go, does light die out over distance or go forever until absorbed? This research explores the tension between focusing students' conceptual change on specific scientific phenomena and their development of integrated understanding. I focus on the importance of connecting students' everyday experiences and intuitions to their science learning. The work reported here characterizes how students see the world through a filter of their own understanding. It explores how individual and social mechanisms in instruction support students as they expand the range of ideas under consideration and distinguish between these ideas using scientific criteria. Instruction supported students as they engaged in argumentation and debate on a set of multimedia evidence items from the World-Wide-Web. An argument editor called SenseMaker was designed and studied with the intent of making individual and group thinking visible during instruction. Over multiple classroom trials, different student cohorts were increasingly supported in scientific argumentation involving systematic coordination of evidence with theoretical ideas about light. Students' knowledge representations were used as mediating "learning artifacts" during classroom debate. Two argumentation conditions were investigated. The Full Scope group prepared to defend either theoretical position in the debate. These students created arguments that included more theoretical conjectures and made more conceptual progress in understanding light. The Personal Scope group prepared to defend their original opinion about the debate. These students produced more acausal descriptions of evidence and theorized less in their arguments. Regardless of students' prior knowledge of light, the Full Scope condition resulted in a more integrated understanding. Results from the research were synthesized in design principles geared towards helping future designers. Sharing and refining cognitive design principles offers a productive focus for developing a design science for education.

[Rationing in German health care with particular consideration of oncology: view points of German stakeholders--a qualitative interview study].

PubMed

Lange, J; Gönner, C; Vollmann, J; Rauprich, O

2015-01-01

Germany is at the beginning of a discussion about possible rationing in the health-care system. Cancer treatment, which is often cost-intensive but not always cost-effective, is frequently considered as a field for rationing. Against this background, we conducted semi-structured, guideline-based interviews with different stakeholders of the German health-care system and analysed them with the help of grounded theory techniques. The goal of the study was to collect the experiences and opinions of members of the German Medical Review Board of the Statutory Health Insurance Funds (MDK), leading officials in central administrations of the German health-care sector and health politicians (members of the Parliamentary Committee for Health of the Federal German Parliament, the Bundestag) regarding cost-considerations in treatment decisions in health care with a special focus on oncology. (1) Cost-considerations have a limited role in the daily routine of the interviewed experts; (2) the interviewed personnel of the MDK were open to discuss rationing, while the group of leading officials was ambivalent and the health politicians rejected rationing and its discussion altogether; (3) the awareness of the opportunity costs of medical services varied with the profession of the interviewee: the members of the MDK saw opportunity costs primarily within the field of medicine, the leading officials noted the opportunity costs for other social services, and the health policy makers interpreted opportunity costs under fiscal budgetary aspects; (4) according to the interviewees, decisions on rationing require a legal basis, which should be based on a broad public discussion and an interdisciplinary debate among experts; (5) defining criteria for rationing was regarded as being outside of the professional competence of the interviewees; however, a preference with regard to the criterion of cost-effectiveness became apparent. The results of this study indicate that the strongest opposition to a debate on rationing in Germany does not stem from the medical, but rather from the political sector. The criteria for rationing suggested in the theoretical debate are in need of a context-sensitive examination and specification for the field of oncology. A possible approach to constructively promote the debate on rationing is a stronger focus on social opportunity costs of health care. The exact role of experts in a discourse on rationing, which was emphasised by the interviewees, requires a thorough determination. It is necessary to differentiate between the roles of impartial experts and stakeholders. Decisions on rationing can ultimately only be legitimised politically by parliament. © Georg Thieme Verlag KG Stuttgart · New York.

A proposed World Council on Epidemiology and Causation: summary of feedback and considerations in an international workshop.

PubMed

Bhopal, Raj

2017-03-01

Rigorous evaluation of associations in epidemiology is essential, especially given big data, data mining, and hypothesis-free analyses. There is a precedent in making judgments on associations in the monographs of the International Agency for Research on Cancer; however, only the carcinogenic effects of exposures are examined. The idea of a World Council of Epidemiology and Causality to undertake rigorous, independent, comprehensive examination of associations has been debated, including in a workshop at the International Epidemiology Association's 20 th World Congress of Epidemiology, 2014. The objective of the workshop was both to, briefly, debate the idea and set out further questions and next steps. The principal conclusion from feedback including from the workshop is that the World Council of Epidemiology and Causality idea, notwithstanding challenges, has promise and deserves more debate. The preferred model is for a small independent body working closely with relevant partners with a distributed approach to tasks. Recommendations are contextualized in contemporary approaches in causal thinking in epidemiology. Copyright © 2017 Elsevier Inc. All rights reserved.

Demand management: enabling patients to use medical care appropriately.

PubMed

Vickery, D M; Lynch, W D

1995-05-01

A rationale is presented for considering demand management as well as supply management (managed care) in the current debate on health care reform. Demand management is the support of individuals so that they may make rational health and medical decisions based on a consideration of benefits and risks. The concept of demand for medical services is examined within a theoretical framework of four components: morbidity, perceived need, patient preference, and nonhealth motives. Two components, perceived need and patient preference, are suggested to offer considerable potential for making utilization more appropriate and reducing costs. Current demand services and potential hazards related to their continued expansion are discussed.

The observability principle and beyond. Reply to comments on "Seeing mental states: An experimental strategy for measuring the observability of other minds" by Cristina Becchio et al.

NASA Astrophysics Data System (ADS)

Becchio, Cristina; Koul, Atesh; Ansuini, Caterina; Bertone, Cesare; Cavallo, Andrea

2018-03-01

Is it possible to directly perceive others' mental states? Mediating the debate between Direct Perception and Inferentialism proponents would require knowing "what counts as an inference and how to tell the difference between inferential and non-inferential processing" [1]. However, few theorists have even attempted to answer the question of what counts as inference. The consequence, as noted by Spaulding [1], is that "given that neither Inferentialists nor DSP [Direct Social Perception, Ed.] proponents specify what they mean by inference, it is hard to tell what exactly each side is affirming and denying. Thus, the debate between Inferentialism and DSP is at an impasse". Similar considerations apply to distinguishing between what is 'observable' versus 'unobservable' [2].

Effects of Climate and Climate Change on Vectors and Vector-Borne Diseases: Ticks Are Different.

PubMed

Ogden, Nick H; Lindsay, L Robbin

2016-08-01

There has been considerable debate as to whether global risk from vector-borne diseases will be impacted by climate change. This has focussed on important mosquito-borne diseases that are transmitted by the vectors from infected to uninfected humans. However, this debate has mostly ignored the biological diversity of vectors and vector-borne diseases. Here, we review how climate and climate change may impact those most divergent of arthropod disease vector groups: multivoltine insects and hard-bodied (ixodid) ticks. We contrast features of the life cycles and behaviour of these arthropods, and how weather, climate, and climate change may have very different impacts on the spatiotemporal occurrence and abundance of vectors, and the pathogens they transmit. Crown Copyright © 2016. Published by Elsevier Ltd. All rights reserved.

Vitalism and the Darwin Debate

NASA Astrophysics Data System (ADS)

Henderson, James

2012-08-01

There are currently both scientific and public debates surrounding Darwinism. In the scientific debate, the details of evolution are in dispute, but not the central thesis of Darwin's theory; in the public debate, Darwinism itself is questioned. I concentrate on the public debate because of its direct impact on education in the United States. Some critics of Darwin advocate the teaching of intelligent design theory along with Darwin's theory, and others seek to eliminate even the mention of evolution from science classes altogether. Many of these critics base their objections on the claim that non-living matter cannot give rise to living matter. After considering some of the various meanings assigned to `vitalism' over the years, I argue that a considerable portion of Darwin deniers support a literal version of vitalism that is not scientifically respectable. Their position seems to be that since life cannot arise naturally, Darwin's theory accomplishes nothing: If it can only account for life forms changing from one to another (even this is disputed by some) but not how life arose in the first place, what's the point? I argue that there is every reason to believe that living and non-living matter differ only in degree, not in kind, and that all conversation about Darwinism should start with the assumption that abiogenesis is possible unless or until compelling evidence of its impossibility is presented. That is, I advocate a position that the burden of proof lies with those who claim "Life only comes from life." Until that case is made, little weight should be given to their position.

The Concept of "First-Generation Student" in the Literature: Implications for South African Higher Education

ERIC Educational Resources Information Center

Heymann, L.; Carolissen, R.

2011-01-01

In the United States first-generation students (FGSs), those who are the first in their families to attend university, are recognised as disadvantaged and receive government support. Amidst affirmative action debates in higher education in South Africa, an increased awareness has emerged about challenges that FGSs in this country face. A…

The Learning Preferences of Digital Learners in K-12 Schools in China

ERIC Educational Resources Information Center

Yang, Junfeng; Huang, Ronghuai; Kinshuk

2016-01-01

Students grown up with digital technology and Internet are called digital natives or net generation. All others, who grew up without so much immersion with digital technologies are called digital immigrants. Researchers held different ideas on whether a new generation of learners existed. One of the foci of the debate is on the appropriateness of…

The Impact of Part-Time Faculty on Student Retention: A Case Study in Higher Education

ERIC Educational Resources Information Center

Smith, Curtis V.

2010-01-01

There has been considerable debate in community colleges over the last forty years regarding the impact of increased use of part-time faculty (PTF) on student learning. It has been argued that part-time faculty fail to provide the same level of teaching quality as full-time faculty (FTF). The purpose of this study was to determine the impact of…

Impacts on non-human biota from a generic geological disposal facility for radioactive waste: some key assessment issues.

PubMed

Robinson, C A; Smith, K L; Norris, S

2010-06-01

This paper provides an overview of key issues associated with the application of currently available biota dose assessment methods to consideration of potential environmental impacts from geological disposal facilities. It explores philosophical, methodological and practical assessment issues and reviews the implications of test assessment results in the context of recent and on-going challenges and debates.

Increasing Student Communication and Spontaneous Language Use in the L2 Classroom: A Careful Consideration of the Flipped Classroom Model

ERIC Educational Resources Information Center

Bachelor, Jeremy W.

2017-01-01

There is an ongoing debate among L2 educators regarding the best way for students to achieve effective communication and language spontaneity. The flipped classroom refers to an educational model where the traditional practice of dedicating class time to direct instruction is flipped so that students receive initial instruction at home and then…

Vertebrate predators have minimal cascading effects on plant production or seed predation in an intact grassland ecosystem

Treesearch

John L. Maron; Dean E. Pearson

2011-01-01

The strength of trophic cascades in terrestrial habitats has been the subject of considerable interest and debate. We conducted an 8-year experiment to determine how exclusion of vertebrate predators, ungulates alone (to control for ungulate exclusion from predator exclusion plots) or none of these animals influenced how strongly a three-species assemblage of rodent...

Subjectivation and Performative Politics--Butler Thinking Althusser and Foucault: Intelligibility, Agency and the Raced-Nationed-Religioned Subjects of Education

ERIC Educational Resources Information Center

Youdell, Deborah

2006-01-01

Judith Butler is perhaps best known for her take-up of the debate between Derrida and Austin over the function of the performative and her subsequent suggestion that the subject be understood as performatively constituted. Another important but less often noted move within Butler's consideration of the processes through which the subject is…

Debating Global Warming in Media Discussion Forums: Strategies Enacted by "Persistent Deniers" and Implications for Schooling

ERIC Educational Resources Information Center

Bowen, G. Michael; Rodger, Valerie

2008-01-01

Newspapers and other media are often used as a source of information on science issues, both by the public and teachers in classrooms. Over six months, we collected discussions of global warming issues from the online forums of a national newspaper. Our analysis of these contributions suggests there is a considerable effort in these forums,…

An Analysis of Current Graduation Thesis Writing by English Majors in Independent Institute

ERIC Educational Resources Information Center

Han, Ying

2014-01-01

The paper takes 414 graduates from ZJU in 2011 and 2012, NIT as a case, analyzing the status of their writing of graduation thesis. It is found that a considerable number of students have problems in selection and report of topics, writing of each part and debating in the whole process of graduation thesis. In view of the situation, based on the…

Losing Sight of the Child? Human Capital Theory and Its Role for Early Childhood Education and Care Policies in Finland and England since the Mid-1990s

ERIC Educational Resources Information Center

Campbell-Barr, Verity; Nygård, Mikael

2014-01-01

The international interest in early childhood education and care (ECEC) by supranational organisations, including the European Union, has grown considerably due to its dual function of sustaining parental employment and fostering child development. Focussing primarily on child development debates around ECEC, this article argues that human capital…

What Makes a Fiat Run? A Consideration of the Nature of Fiat Power in Academic Policy Deliberation.

ERIC Educational Resources Information Center

Fadely, Dean

In the game-like world of competitive tournament debating, fiat power is simply another rule of the game, a way of saying "hypothetically" or "for the sake of argument let us assume this affirmative plan to be implemented." While fiat power is just a way of saying "let's pretend," there are limits to the pretense. For…

The Arizona Education Tax Credit and Hidden Considerations of Justice: Why We Ought To Fight Poverty, Not Taxes.

ERIC Educational Resources Information Center

Moses, Michele S.

2000-01-01

Describes the Arizona education tax credit law as a voucher plan in disguise, and argues that the concept of justice underlying the law is an element largely missing from the school choice debate. Calls on educators and policymakers to concentrate on efforts to help needy students rather than to channel tax dollars toward self-interested ends.…

Ethical Mindfulness and Reflexivity: Managing a Research Relationship with Children and Young People in a 14-Year Qualitative Longitudinal Research (QLR) Study

ERIC Educational Resources Information Center

Warin, Jo

2011-01-01

This article draws on the articulation of a value for reflexivity that has accumulated within qualitative methods debates in the past decade. It demonstrates how reflexivity is interwoven with the concept of ethical mindfulness. The argument has developed from a consideration of the ethical dilemmas that were a salient aspect of an ongoing…

The Federal Government's Deinstitutionalization Program Initiatives: A Status Report (A Litany of Reports, Studies, Recommendations, Policy Debates, and Even Some Progress).

ERIC Educational Resources Information Center

Ross, E. Clarke

1979-01-01

Analysis of six federal government studies on deinstitutionalization is followed by a discussion of initiatives enacted by the 95th Congress and proposals under consideration in the 96th. Among studies described are reports by the U.S. Government Accounting Office ("Returning the Mentally Disabled to the Community: Government Needs to Do…

Educating for Location? The Policy Context of "Becoming Asia-Literate" in Five Western Countries/Regions in the 1990s

ERIC Educational Resources Information Center

Pang, David

2005-01-01

This article examines the educational policy responses by five western countries/regions to the "Asian economic miracle" in the 1990s. It begins by stating that the idea of the global economic context has assumed considerable importance in the current educational thinking and debates. It then shows that Asia has been thematized in the…

Why Aren't We There Yet? Taking Personal Responsibility for Creating an Inclusive Campus. An ACPA Publication

ERIC Educational Resources Information Center

Arminio, Jan, Ed.; Torres, Vasti, Ed.; Pope, Raechele L., Ed.

2012-01-01

Despite seeming endless debate and public attention given to the issue for several decades, those committed to creating welcoming and engaging campus environments for all students recognize that there is considerably more work to be done, and ask "Why aren't we there yet, and when will we be done?" While our campuses have evolved from being…

The Evolving Domestic Forum for National Security Debates

DTIC Science & Technology

1974-01-01

of USAWC in March 1974, he was Director, Social Science Studies, Westinghouse Center for Advanced Studies and Analyses. He is the author of n umeIOUS...American social and cultural contex ts, which necessarily overlap the areas of politics, economics, foreign relations, and national security affairs. At...preserve its integrity if individual conscience is accorded a priority overriding all other considerations? - Which value, achievement or equality

Securing Annuities for Federal Employees Act of 2012

THOMAS, 112th Congress

Rep. Ross, Dennis A. [R-FL-12

2012-01-24

House - 02/14/2012 Rules Committee Resolution H. Res. 547 Reported to House. The resolution provides for one hour of debate on H.R. 3408. All points of order against consideration of the bill are waived. Specified amendments printed in part A of the report accompanying this... (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

What Are the Communication Considerations for Parents of Deaf and Hard-of-Hearing Children? NIDCD Fact Sheet

ERIC Educational Resources Information Center

National Institute on Deafness and Other Communication Disorders (NIDCD), 2006

2006-01-01

Deafness or hearing impairment affects not only a child who is deaf or has a hearing loss, but also the child's family, friends, and teachers. For hundreds of years, people have debated the best ways to develop communication skills and provide education for deaf and hard-of-hearing children. This fact sheet presents a few points upon which…

The Beginning of Civic Universities: A Survey of Societal and Internal Influences. Yale Higher Education Program Working Paper.

ERIC Educational Resources Information Center

Jones, David R.

The history of universities in their social context is not a merely antiquarian study; it is the soundest basis for consideration of the contemporary university and its problems. The most frequent debate, that of the ivory tower, is really a question of the form and efficiency of the university's articulation with society at large. The…

SLA Research and L2 Pedagogy: Misapplications and Questions of Relevance

ERIC Educational Resources Information Center

Spada, Nina

2015-01-01

There has been considerable debate about the relevance and applicability of SLA theory and research for L2 pedagogy. There are those who maintain that SLA must be applicable to L2 pedagogy: a view based on the argument that because SLA is a subfield of applied linguistics, it should have direct relevance to L2 teaching. Others take the view that…

Educating nurses to protect the past or to advance health care?: A polemic.

PubMed

Nay, R; Pearson, A

2001-01-01

Internationally, nursing is challenged by recruitment and retention issues. On the one hand nursing is expanding and extending practice whilst on the other, lesser skilled workers are undertaking many roles which were previously fulfilled by nurses. This opinion paper contextualises the current debate and outlines many of the reasons that have been proffered for the apparent shortage. It then progresses to suggest strategies that may ensure nursing remains relevant to contemporary health care. Essentially a presentation of the authors' views, the intent of the paper is to generate debate.

Molecular tools for bathing water assessment in Europe: Balancing social science research with a rapidly developing environmental science evidence-base.

PubMed

Oliver, David M; Hanley, Nick D; van Niekerk, Melanie; Kay, David; Heathwaite, A Louise; Rabinovici, Sharyl J M; Kinzelman, Julie L; Fleming, Lora E; Porter, Jonathan; Shaikh, Sabina; Fish, Rob; Chilton, Sue; Hewitt, Julie; Connolly, Elaine; Cummins, Andy; Glenk, Klaus; McPhail, Calum; McRory, Eric; McVittie, Alistair; Giles, Amanna; Roberts, Suzanne; Simpson, Katherine; Tinch, Dugald; Thairs, Ted; Avery, Lisa M; Vinten, Andy J A; Watts, Bill D; Quilliam, Richard S

2016-02-01

The use of molecular tools, principally qPCR, versus traditional culture-based methods for quantifying microbial parameters (e.g., Fecal Indicator Organisms) in bathing waters generates considerable ongoing debate at the science-policy interface. Advances in science have allowed the development and application of molecular biological methods for rapid (~2 h) quantification of microbial pollution in bathing and recreational waters. In contrast, culture-based methods can take between 18 and 96 h for sample processing. Thus, molecular tools offer an opportunity to provide a more meaningful statement of microbial risk to water-users by providing near-real-time information enabling potentially more informed decision-making with regard to water-based activities. However, complementary studies concerning the potential costs and benefits of adopting rapid methods as a regulatory tool are in short supply. We report on findings from an international Working Group that examined the breadth of social impacts, challenges, and research opportunities associated with the application of molecular tools to bathing water regulations.

Computational study of the binding of CuII to Alzheimer's amyloid-beta peptide: do Abeta42 and Abeta40 bind copper in identical fashion?

PubMed

Mantri, Yogita; Fioroni, Marco; Baik, Mu-Hyun

2008-11-01

One of the many hypotheses on the pathogenesis of Alzheimer's disease is that the amyloid-beta peptide (Abeta) binds CuII and can catalytically generate H2O2, leading to oxidative damage in brain tissues. For a molecular level understanding of such catalysis it is critical to know the structure of the Abeta-CuII complex precisely. Unfortunately, no high-resolution structure is available to date and there is considerable debate over the copper coordination environment with no clear consensus on which residues are directly bound to CuII. Considering all plausible isomers of the copper-bound Abeta42 and Abeta40 using a combination of density functional theory and classical molecular dynamics methods, we report an atomic resolution structure for each possible complex. We evaluated the relative energies of these isomeric structures and surprisingly found that Abeta42 and Abeta40 display very different binding modes, suggesting that shorter peptides that are truncated at the C-terminus may not be realistic models for understanding the chemistry of the most neurotoxic peptide, Abeta42.

From 'beastly philosophy' to medical genetics: eugenics in Russia and the Soviet Union.

PubMed

Krementsov, Nikolai

2011-01-01

This essay offers an overview of the three distinct periods in the development of Russian eugenics: Imperial (1900-1917), Bolshevik (1917-1929), and Stalinist (1930-1939). Began during the Imperial era as a particular discourse on the issues of human heredity, diversity, and evolution, in the early years of the Bolshevik rule eugenics was quickly institutionalized as a scientific discipline--complete with societies, research establishments, and periodicals--that aspired an extensive grassroots following, generated lively public debates, and exerted considerable influence on a range of medical, public health, and social policies. In the late 1920s, in the wake of Joseph Stalin's 'Great Break', eugenics came under intense critique as a 'bourgeois' science and its proponents quickly reconstituted their enterprise as 'medical genetics'. Yet, after a brief period of rapid growth during the early 1930s, medical genetics was dismantled as a 'fascist science' towards the end of the decade. Based on published and original research, this essay examines the factors that account for such an unusual--as compared to the development of eugenics in other locales during the same period--historical trajectory of Russian eugenics.

Malaria parasite mutants with altered erythrocyte permeability: a new drug resistance mechanism and important molecular tool

PubMed Central

Hill, David A; Desai, Sanjay A

2010-01-01

Erythrocytes infected with plasmodia, including those that cause human malaria, have increased permeability to a diverse collection of organic and inorganic solutes. While these increases have been known for decades, their mechanistic basis was unclear until electrophysiological studies revealed flux through one or more ion channels on the infected erythrocyte membrane. Current debates have centered on the number of distinct ion channels, which channels mediate the transport of each solute and whether the channels represent parasite-encoded proteins or human channels activated after infection. This article reviews the identification of the plasmodial surface anion channel and other proposed channels with an emphasis on two distinct channel mutants generated through in vitro selection. These mutants implicate parasite genetic elements in the parasite-induced permeability, reveal an important new antimalarial drug resistance mechanism and provide tools for molecular studies. We also critically examine the technical issues relevant to the detection of ion channels by electrophysiological methods; these technical considerations have general applicability for interpreting studies of various ion channels proposed for the infected erythrocyte membrane. PMID:20020831

The circadian clock stops ticking during deep hibernation in the European hamster

PubMed Central

Revel, Florent G.; Herwig, Annika; Garidou, Marie-Laure; Dardente, Hugues; Menet, Jérôme S.; Masson-Pévet, Mireille; Simonneaux, Valérie; Saboureau, Michel; Pévet, Paul

2007-01-01

Hibernation is a fascinating, yet enigmatic, physiological phenomenon during which body temperature and metabolism are reduced to save energy. During the harsh season, this strategy allows substantial energy saving by reducing body temperature and metabolism. Accordingly, biological processes are considerably slowed down and reduced to a minimum. However, the persistence of a temperature-compensated, functional biological clock in hibernating mammals has long been debated. Here, we show that the master circadian clock no longer displays 24-h molecular oscillations in hibernating European hamsters. The clock genes Per1, Per2, and Bmal1 and the clock-controlled gene arginine vasopressin were constantly expressed in the suprachiasmatic nucleus during deep torpor, as assessed by radioactive in situ hybridization. Finally, the melatonin rhythm-generating enzyme, arylalkylamine N-acetyltransferase, whose rhythmic expression in the pineal gland is controlled by the master circadian clock, no longer exhibits day/night changes of expression but constantly elevated mRNA levels over 24 h. Overall, these data provide strong evidence that in the European hamster the molecular circadian clock is arrested during hibernation and stops delivering rhythmic output signals. PMID:17715068

The clinical investigator-subject relationship: a contextual approach

PubMed Central

2009-01-01

Background The nature of the relationship between a clinical investigator and a research subject has generated considerable debate because the investigator occupies two distinct roles: clinician and scientist. As a clinician, the investigator has duties to provide the patient with optimal care and undivided loyalty. As a scientist, the investigator has duties to follow the rules, procedures and methods described in the protocol. Results and conclusion In this article, I present a contextual approach to the investigator-subject relationship. The extent of the investigator's duty to provide the patient/subject with clinical care can vary from one situation to the next, as a function of several factors, including: the research design, benefits and risks of the research; the subject's reasonable expectations, motivations, and vulnerabilities; the investigator's ability to benefit the subject; and the investigator's prior relationship with the subject. These and other factors need to be considered when determining the clinical investigator's obligations to provide clinical care to human research subjects. In some research contexts, the investigator has extensive clinical obligations to the patient/subject; in others, the investigator has minimal ones. PMID:19958542

Climate, environmental and socio-economic change: weighing up the balance in vector-borne disease transmission.

PubMed

Parham, Paul E; Waldock, Joanna; Christophides, George K; Hemming, Deborah; Agusto, Folashade; Evans, Katherine J; Fefferman, Nina; Gaff, Holly; Gumel, Abba; LaDeau, Shannon; Lenhart, Suzanne; Mickens, Ronald E; Naumova, Elena N; Ostfeld, Richard S; Ready, Paul D; Thomas, Matthew B; Velasco-Hernandez, Jorge; Michael, Edwin

2015-04-05

Arguably one of the most important effects of climate change is the potential impact on human health. While this is likely to take many forms, the implications for future transmission of vector-borne diseases (VBDs), given their ongoing contribution to global disease burden, are both extremely important and highly uncertain. In part, this is owing not only to data limitations and methodological challenges when integrating climate-driven VBD models and climate change projections, but also, perhaps most crucially, to the multitude of epidemiological, ecological and socio-economic factors that drive VBD transmission, and this complexity has generated considerable debate over the past 10-15 years. In this review, we seek to elucidate current knowledge around this topic, identify key themes and uncertainties, evaluate ongoing challenges and open research questions and, crucially, offer some solutions for the field. Although many of these challenges are ubiquitous across multiple VBDs, more specific issues also arise in different vector-pathogen systems. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

Linear versus quadratic portfolio optimization model with transaction cost

NASA Astrophysics Data System (ADS)

Razak, Norhidayah Bt Ab; Kamil, Karmila Hanim; Elias, Siti Masitah

2014-06-01

Optimization model is introduced to become one of the decision making tools in investment. Hence, it is always a big challenge for investors to select the best model that could fulfill their goal in investment with respect to risk and return. In this paper we aims to discuss and compare the portfolio allocation and performance generated by quadratic and linear portfolio optimization models namely of Markowitz and Maximin model respectively. The application of these models has been proven to be significant and popular among others. However transaction cost has been debated as one of the important aspects that should be considered for portfolio reallocation as portfolio return could be significantly reduced when transaction cost is taken into consideration. Therefore, recognizing the importance to consider transaction cost value when calculating portfolio' return, we formulate this paper by using data from Shariah compliant securities listed in Bursa Malaysia. It is expected that, results from this paper will effectively justify the advantage of one model to another and shed some lights in quest to find the best decision making tools in investment for individual investors.

Comparative Study Between Wind and Photovoltaic (PV) Systems

NASA Astrophysics Data System (ADS)

Taha, Wesam

This paper reviews two renewable energy systems; wind and photovoltaic (PV) systems. The common debate between the two of them is to conclude which one is better, in terms of cost and efficiency. Therefore, comparative study, in terms of cost and efficiency, is attempted. Regarding total cost of both, wind and PV systems, many parameters must be taken into consideration such as availability of energy (either wind or solar), operation and maintenance, availability of costumers, political influence, and the components used in building the system. The main components and parameters that play major role in determining the overall efficiency of wind systems are the wind turbine generator (WTG), gearbox and control technologies such as power, and speed control. On the other hand, in grid-connected PV systems (GCPVS), converter architecture along with maximum power point tracking (MPPT) algorithm and inverter topologies are the issues that affects the efficiency significantly. Cost and efficiency analyses of both systems have been carried out based on the statistics available till today and would be useful in the progress of renewable energy penetration throughout the world.

Some considerations on the current debate about typing resolution in solid organ transplantation.

PubMed

Vogiatzi, Paraskevi

2016-01-01

The shortage of suitable organs and achieved tolerance are uncontested main concerns in transplantation. Long waiting lists for deceased donors and limited numbers of living donors are the current scenarios. Kidney grafts from living donors have better overall survival compared to cadaveric and require less aggressive immunosuppressive regimens. The human leukocyte antigen (HLA) labs have the key role to test the recipient and donors compatibility based on typing and antibody profile. The current standard molecular procedure in solid organ transplantation is low-resolution typing, at the antigen level. In this commentary, the merits of high versus low degree of typing resolution in solid organ transplantation are discussed. Critical questions and reasons to bring high-resolution typing as a routine test in health system are considered. Specifically, with the introduction of the next-generation sequencing (NGS) in HLA, the pros and cons in living donation and benefits after deceased donation are critically evaluated. NGS has the potential to improve the transplant rates and the overall graft survival. Alternative strategies to increase in demanding the number of transplants are briefly highlighted.

Controversies in breast cancer: adjuvant and neoadjuvant therapy.

PubMed

Montemurro, Filippo; Redana, Stefania; Valabrega, Giorgio; Aglietta, Massimo

2005-06-01

Initial randomised studies of chemotherapy and endocrine therapy showed that systemic treatments had a substantial impact on the survival of women with early breast cancer. The original assumption was that the efficacy of these treatments was limited to those patients presenting with more adverse prognostic features. Subsequently, meta-analyses of randomised trials revealed that the benefits of chemotherapy and endocrine therapy are not mutually exclusive and extend to all the prognostic subgroups. However, the absolute benefit varies according to baseline characteristics such as tumour stage and other biological factors. Over the last 10 years, considerable progress has been made with the introduction of new drugs into the adjuvant and neoadjuvant treatment of women with breast cancer. Taxanes and third-generation aromatase inhibitors are providing proof of additional benefits compared with standard reference treatments. In parallel, research on the biology of breast cancer is establishing novel prognostic and predictive factors, which may allow better treatment tailoring. Currently, however, women with early breast cancer and their doctors face the difficult task of making therapeutic decisions often based on early results from positive studies. In a disease where follow up is crucial to fully assess the benefit and long-term toxicities of an intervention, current knowledge leaves unanswered questions that generate debate and controversy. This review will summarise recent results from randomised trials of adjuvant and neoadjuvant therapy in women with early breast cancer and focus on the current controversies.

Ensuring the Criminological Skills of the Next Generation: A Case Study on the Importance of Enhanced Quantitative Method Teaching Provision

ERIC Educational Resources Information Center

Chamberlain, John Martyn

2017-01-01

Against the backdrop of contemporary debates surrounding the public role of criminology, this article argues that a key barrier to ensuring that the next generation of criminologists is equipped with the skills necessary to engage in critical forms of citizenship, is the quantitative "skills gap" that undergraduate students possess as a…

The extinct animal show: the paleoimagery tradition and computer generated imagery in factual television programs.

PubMed

Campbell, Vincent

2009-03-01

Extinct animals have always been popular subjects for the media, in both fiction, and factual output. In recent years, a distinctive new type of factual television program has emerged in which computer generated imagery is used extensively to bring extinct animals back to life. Such has been the commercial audience success of these programs that they have generated some public and academic debates about their relative status as science, documentary, and entertainment, as well as about their reflection of trends in factual television production, and the aesthetic tensions in the application of new media technologies. Such discussions ignore a crucial contextual feature of computer generated extinct animal programs, namely the established tradition of paleoimagery. This paper examines a selection of extinct animal shows in terms of the dominant frames of the paleoimagery genre. The paper suggests that such an examination has two consequences. First, it allows for a more context-sensitive evaluation of extinct animal programs, acknowledging rather than ignoring relevant representational traditions. Second, it allows for an appraisal and evaluation of public and critical reception of extinct animal programs above and beyond the traditional debates about tensions between science, documentary, entertainment, and public understanding.

The Perfect Womb: Promoting Equality of (Fetal) Opportunity.

PubMed

Kendal, Evie

2017-06-01

This paper aims to address how artificial gestation might affect equality of opportunity for the unborn and any resultant generation of "ectogenetic" babies. It will first explore the current legal obstacles preventing the development of ectogenesis, before looking at the benefits of allowing this technology to control fetal growth and development. This will open up a discussion of the treatment/enhancement divide regarding the use of reproductive technologies, a topic featured in various bioethical debates on the subject. Using current maternity practices in Western society as a comparator, this paper will conclude that neither naturally nor artificially gestated fetuses have interests that can conflict with those of potential parents who might want to use this technology to control fetal development. Such control may include selective implantation of embryos of a desired gender, deliberate choice of genetic traits, or maintenance of an ideal incubation environment to avoid fetal damage. Objections on the basis of disability as well as concerns regarding eugenics will be addressed. The paper will conclude that none of these objections are compelling grounds to prevent the development and use of ectogenesis technologies for the purpose of achieving specific reproductive goals, particularly when compared to current practices in pre-implantation genetic diagnosis and selective abortion on the grounds of undesired traits. As such, when deciding whether to support ectogenesis research, the enduring interests of parents must be the primary consideration, with societal concerns regarding potential misuse the only valid secondary consideration.

Hypernetwork generation for multi-modal transportation system modeling.

DOT National Transportation Integrated Search

2013-04-01

The transportation debate has evolved in recent decades to include ideas such as sustainability and livability alongside mobility and safety. Definitional complexities aside, there is no doubt that this evolution has created a national transportation...

Yellowstone wolves and the forces that structure natural systems.

PubMed

Dobson, Andy P

2014-12-01

Since their introduction in 1995 and 1996, wolves have had effects on Yellowstone that ripple across the entire structure of the food web that defines biodiversity in the Northern Rockies ecosystem. Ecological interpretations of the wolves have generated a significant amount of debate about the relative strength of top-down versus bottom-up forces in determining herbivore and vegetation abundance in Yellowstone. Debates such as this are central to the resolution of broader debates about the role of natural enemies and climate as forces that structure food webs and modify ecosystem function. Ecologists need to significantly raise the profile of these discussions; understanding the forces that structure food webs and determine species abundance and the supply of ecosystem services is one of the central scientific questions for this century; its complexity will require new minds, new mathematics, and significant, consistent funding.

Why primary care practices should become digital health information hubs for their patients.

PubMed

Baird, Aaron; Nowak, Samantha

2014-11-25

Two interesting health care trends are currently occurring: 1) patient-facing technologies, such as personal health records, patient portals, and mobile health apps, are being adopted at rapid rates, and 2) primary care, which includes family practice, is being promoted as essential to reducing health care costs and improving health care outcomes. While these trends are notable and commendable, both remain subject to significant fragmentation and incentive misalignments, which has resulted in significant data coordination and value generation challenges. In particular, patient-facing technologies designed to increase care coordination, often fall prey to the very digital fragmentation issues they are supposed to overcome. Additionally, primary care providers are treating patients that may have considerable health information histories, but generating a single view of such multi-source data is nearly impossible. We contribute to this debate by proposing that primary care practices become digital health information hubs for their patients. Such hubs would offer health data coordination in a medically professional setting with the benefits of expert, trustworthy advice coupled with active patient engagement. We acknowledge challenges including: costs, information quality and provenance, willingness-to-share information and records, willingness-to-use (by both providers and patients), primary care scope creep, and determinations of technical and process effectiveness. Even with such potential challenges, we strongly believe that more debate is needed on this topic prior to full implementation of various health information technology incentives and reform programs currently being designed and enacted throughout the world. Ultimately, if we do not provide a meaningful way for the full spectrum of health information to be used by both providers and patients, especially early in the health care continuum, effectively improving health outcomes may remain elusive. We view the primary care practice as a central component of digital information coordination, especially when considering the current challenges of digital health information fragmentation. Given these fragmentation issues and the emphasis on primary care as central to improving health and lower overall health care costs, we suggest that primary care practices should embrace their evolving role and should seek to become digital health information hubs for their patients.

"One man's trash is another man's treasure": exploring economic and moral subtexts of the "organ shortage" problem in public views on organ donation.

PubMed

Schicktanz, S; Schweda, M

2009-08-01

The debate over financial incentives and market models for organ procurement represents a key trend in recent bioethics. In this paper, we wish to reassess one of its central premises-the idea of organ shortage. While the problem is often presented as an objective statistical fact that can be taken for granted, we will take a closer look at the underlying framework expressed in the common rhetoric of "scarcity", "shortage" or "unfulfilled demand". On the basis of theoretical considerations as well as a socioempirical examination of public attitudes, we will argue that this rhetoric has an economic subtext that imbues the debate with normative premises that have far-reaching social and ethical consequences and need to be made explicit and discussed.

Is Linus Pauling, a vitamin C advocate, just making much ado about nothing? (Review).

PubMed

Kodama, M; Kodama, T

1994-01-01

Clinical use of vitamin C has been the subject of much debate in both the USA and Japan. We examine a number of topics to clarify the reasons for the confrontation of opinion between the pros and the cons as to the medical usefulness of this vitamin. We refer to our own experiences on the use of vitamin C infusion treatment for the control of either diabetes mellitus or autoimmune disease and allergy to show the importance of pharmacological considerations in the assessment of the effect of vitamin C. We also refer to a number of scientific debates to prove that a shift of paradigm is indispensable for getting a full comprehension of the benefits of vitamin C including the control of both diabetes mellitus and autoimmune disease/allergy complex.

Positive argument for debate in J Neural Transmission: Alzheimer's disease: are we intervening too late? Yes, by years if not decades.

PubMed

Shea, Thomas B; Remington, Ruth

2012-12-01

The ongoing debate as to whether we are or are not early enough in treatment for Alzheimer's disease presents distinct vantage points. Points expressed range from stressing the need for early preventive measures to highlighting the failure of "alternative" therapies, and concluding that we are unfortunately doing all that we can at present. Herein, we stress the worth of nutritional intervention, and review why such studies are often inherently compromised. We conclude that considerable education is needed to advance lifestyle modifications early enough to obtain their optimal effect, and instead of positioning "classical" interventions against "alternative" interventions, the combinations of both may impart maximal benefit. The introduction of novel detection methods at the earliest indications of cognitive impairment may provide a window of opportunity for initiation of preventative approaches.

Widening the debate about conflict of interest: addressing relationships between journalists and the pharmaceutical industry.

PubMed

Lipworth, Wendy; Kerridge, Ian; Sweet, Melissa; Jordens, Christopher; Bonfiglioli, Catriona; Forsyth, Rowena

2012-08-01

The phone-hacking scandal that led to the closure of the News of the World newspaper in Britain has prompted international debate about media practices and regulation. It is timely to broaden the discussion about journalistic ethics and conduct to include consideration of the impact of media practices upon the population's health. Many commercial organisations cultivate relationships with journalists and news organisations with the aim of influencing the content of health-related news and information communicated through the media. Given the significant influence of the media on the health of individuals and populations, we should be alert to the potential impact of industry-journalist relationships on health care, health policy and public health. The approach taken by the medical profession to its interactions with the pharmaceutical industry provides a useful model for management of industry influence.

Information processing and dynamics in minimally cognitive agents.

PubMed

Beer, Randall D; Williams, Paul L

2015-01-01

There has been considerable debate in the literature about the relative merits of information processing versus dynamical approaches to understanding cognitive processes. In this article, we explore the relationship between these two styles of explanation using a model agent evolved to solve a relational categorization task. Specifically, we separately analyze the operation of this agent using the mathematical tools of information theory and dynamical systems theory. Information-theoretic analysis reveals how task-relevant information flows through the system to be combined into a categorization decision. Dynamical analysis reveals the key geometrical and temporal interrelationships underlying the categorization decision. Finally, we propose a framework for directly relating these two different styles of explanation and discuss the possible implications of our analysis for some of the ongoing debates in cognitive science. Copyright © 2014 Cognitive Science Society, Inc.

Medical confidentiality in the late nineteenth and early twentieth centuries: an Anglo-German comparison1

PubMed Central

2012-01-01

Summary Professional secrecy of doctors became an issue of considerable medico-legal and political debate in the late nineteenth and early twentieth centuries in both Germany and England, although the legal preconditions for this debate were quite different in the two countries. While in Germany medical confidentiality was a legal obligation and granted in court, no such statutory recognition of doctors’ professional secrecy existed in England. This paper is a comparative analysis of medical secrecy in three key areas - divorce trials, venereal disease and abortion - in both countries. Based on sources from the period between c.1870 and 1939, our paper shows how doctors tried to define the scope of professional secrecy as an integral part of their professional honour in relation to important matters of public health. PMID:21077462

Direct-to-consumer genomics on the scales of autonomy

PubMed Central

Vayena, Effy

2015-01-01

Direct-to-consumer (DTC) genetic services have generated enormous controversy from their first emergence. A dramatic recent manifestation of this is the Food and Drug Administration's (FDA) cease and desist order against 23andMe, the leading provider in the market. Critics have argued for the restrictive regulation of such services, and even their prohibition, on the grounds of the harm they pose to consumers. Their advocates, by contrast, defend them as a means of enhancing the autonomy of those same consumers. Autonomy emerges as a key battle-field in this debate, because many of the ‘harm’ arguments can be interpreted as identifying threats to autonomy. This paper assesses whether DTC genomic services are a threat to, or instead, an enhancement of, personal autonomy. It deploys Joseph Raz's account of personal autonomy, with its emphasis on choice from a range of valuable options. It then seeks to counter claims that DTC genomics threatens autonomy because it involves manipulation in contravention of consumers’ independence or because it does not generate valuable options which can be meaningfully engaged with by consumers. It is stressed that the value of the options generated by DTC genomics should not be judged exclusively from the perspective of medical actionability, but should take into consideration plural utilities. Finally, the paper ends by broaching policy recommendations, suggesting that there is a strong autonomy-based argument for permitting DTC genomic services, and that the key question is the nature of the regulatory conditions under which they should be permitted. The discussion of autonomy in this paper helps illuminate some of these conditions. PMID:24797610

JPRS Report, West Europe

DTIC Science & Technology

1987-06-22

with another difficult issue. KRF has invested considerable prestige in the discussion of the artificial insemination law. KRF is putting pressure on...immediately halt the widespread use of artificial fertilizer, which was seen as one of the main causes of groundwater pollution. This struck at the...the same side. 45 Insemination and Taxes In addition there were the many disagreements in last fall’s budget debate. The three must also deal

Military NGO Interaction: The Value of Cultural Competence

DTIC Science & Technology

2013-04-08

18-04-2013 2. REPORT TYPE Master of Military Studies Research Paper 3. DATES COVERED (From - To) September 2012 - April 2013 4. TITLE AND...Force and the American Red Cross. There has also been considerable discussion of the value of cultural training and cultural competence* This paper ...Definitions of the term “cultural competence” are still being debated. This paper will use the definition proposed by Brian R

Digital Natives and Digital Immigrants: A Study of Information Technology and Information Systems (IT/IS) Usage between Students and Faculty of Nigerian Universities

ERIC Educational Resources Information Center

Ololube, Nwachukwu Prince; Kpolovie, Peter James; Amaele, Samuel; Amanchukwu, Rose N.; Briggs, Teinye

2013-01-01

It is presumed that Nigerian students and teachers have been unable to find effective ways to use technology in the classroom and other aspects of their teaching and learning. Yet, considerable debate remains over the most efficient techniques and procedures to measure students and faculties information technology and information systems (IT/IS)…

Wallace, Darwin and Ternate 1858.

PubMed

Smith, Charles H

2014-06-20

Recent debates on the mailing date of Alfred Russel Wallace's 'Ternate essay' to Charles Darwin in the spring of 1858 have ignored certain details that, once taken into account, alter the matter considerably. Here, a closer look is taken at the critical question of whether Wallace's manuscript-accompanying letter represented a reply to the Darwin letter that arrived in Ternate on 9 March; it is concluded that it very probably did not.

Healing the Wounds of War and More: An Integrative Approach to Peace--The Work of Adam Curle and Others with Mir i dobro in Zupanja, Croatia.

ERIC Educational Resources Information Center

Mitchels, Barbara

2003-01-01

Examines practical implications of Curle's approach to psychological aspects of conflict and peacemaking as evidenced in the Mir i dobro project in Zupanja, taking into consideration some of the current debates concerning treatment of psychological trauma, including validity of the diagnosis of posttraumatic stress disorder and use of so-called…

Correlation-Induced Changes of Spectra

DTIC Science & Technology

1989-12-01

tances has been one of the central have been observed etperimental- other end of the frequency spec- issues of debate among astrono - ly could be...limited consideration by astrono - I mers. in the updated theory, described in the Nov. 13 PHYSICAL REVIEw LETTERS, Wolf outlines a more general - and...billions of light-years apart. Many astrono - mers-ncluding Christopher L. Carilli of Harvard University, who with two colleagues found the most recent

2016 CAPS ethics session/Ein debate: 1. Regionalization of pediatric surgical care 2. Ethical introduction of surgical innovation 3. Addressing stress in a surgical practice: resiliency, well-being, and burnout.

PubMed

Bagwell, Charles E; Chiu, Priscilla; Fecteau, Annie; Gow, Kenneth W; Mueller, Claudia M; Price, David; Zigman, Andrew F

2017-05-01

The following is the conference proceeding of the Second Ein Debate from the 48th Annual Meeting of the Canadian Association of Paediatric Surgeons held in Vancouver, BC, from September 22 to 24, 2016. The three main topics for debate, as prepared by the members of the CAPS Ethics Committee, are: 1. Regionalization of care: pros and cons, 2. Innovation in clinical care: ethical considerations, and 3. Surgeon well-being: caring for the caregiver. The authors of this paper, as participants in the debate, were assigned their positions at random. Therefore, the opinions they express within this summary might not reflect their own viewpoints. In the first discussion, arguments for and against the regionalization of pediatric surgical care are discussed, primarily in the context of a case of BA. In the pro argument, the evidence and lessons learned from different European countries are explored as well as different models to provide the best BA care outside of large teaching centers. In the counterargument, the author explains how regionalization of care could be detrimental for the patient, the family, the regional center, and for the health care system in general. In the debate on surgical innovation the authors define surgical innovation. They review the pertinent ethical principles, explore a model for its implementation, and the role of the institution at which the innovation is proposed. In the third section, surgeon well-being is examined, and recent literature on surgeon resiliency and burnout both at the attending and resident level is reviewed. Copyright © 2017 Elsevier Inc. All rights reserved.

The return of the Inseminator: Eutelegenesis in past and contemporary reproductive ethics.

PubMed

McMillan, John

2007-06-01

Eugenicists in the 1930s and 1940s emphasised our moral responsibilities to future generations and the importance of positively selecting traits that would benefit humanity. In 1935 Herbert Brewer recommended 'Eutelegenesis' (artificial insemination with sperm from specially selected males) so that that future generations are not only protected from hereditary disease but also become more intelligent and fraternal than us. The development of these techniques for human use and animal husbandry was the catalyst for the cross fertilization of moral ideas and the development of a critical procreative morality. While eugenicists argued for a new critical morality, religious critics argued against artificial insemination because of its potential to damage important moral institutions. The tension between critical and conservative procreative morality is a feature of the contemporary debates about reproductive technologies. This and some of the other aspects of the early and contemporary debates about artificial insemination and reproductive technologies are discussed in this article.

The legacy of 'normalisation': the role of classical and contemporary criminological theory in understanding young people's drug use.

PubMed

Measham, Fiona; Shiner, Michael

2009-11-01

Since it began in the mid-1990s, the debate surrounding the normalisation of adolescent recreational drug use has attracted considerable attention and has tended to polarise opinion within the field. In this article two of the main protagonists in the debate come together to discuss its legacy. Focusing on the twin themes of continuity and change the authors begin by considering the relevance of early developments in the sociology of drug use, noting that this earlier work anticipated much that has recently been written on the subject, including the emphasis on hedonism and consumption in leisure lifestyles. From here they go on to critically reflect on the role that structure and agency have played in the normalisation debate, suggesting that the original thesis underplayed the role of structural influences in favour of a rational action model of adolescent drug use. In their more recent work, both authors have come to emphasise how drug use is shaped by an interplay between social structure and human agency. While some areas of disagreement remain, they agree that normalisation is best understood as a contingent process negotiated by distinct social groups operating in bounded situations.

Does bad inference drive out good?

PubMed

Marozzi, Marco

2015-07-01

The (mis)use of statistics in practice is widely debated, and a field where the debate is particularly active is medicine. Many scholars emphasize that a large proportion of published medical research contains statistical errors. It has been noted that top class journals like Nature Medicine and The New England Journal of Medicine publish a considerable proportion of papers that contain statistical errors and poorly document the application of statistical methods. This paper joins the debate on the (mis)use of statistics in the medical literature. Even though the validation process of a statistical result may be quite elusive, a careful assessment of underlying assumptions is central in medicine as well as in other fields where a statistical method is applied. Unfortunately, a careful assessment of underlying assumptions is missing in many papers, including those published in top class journals. In this paper, it is shown that nonparametric methods are good alternatives to parametric methods when the assumptions for the latter ones are not satisfied. A key point to solve the problem of the misuse of statistics in the medical literature is that all journals have their own statisticians to review the statistical method/analysis section in each submitted paper. © 2015 Wiley Publishing Asia Pty Ltd.

Capacity Payments in Restructured Markets under Low and High Penetration Levels of Renewable Energy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jenkin, Thomas; Beiter, Philipp; Margolis, Robert

There is considerable debate about the degree to which restructured markets perform successfully in their use of capacity markets. In providing appropriate incentives for new and existing generation to meet reliability requirements, a variety of capacity market designs have developed across RTOs and ISOs in the United States and internationally. Growing levels of variable renewable energy (VRE) resources arguably create new challenges for capacity market designs, because VREs suppress energy prices while providing relatively little capacity, with these effects increase with VRE penetration. The purpose of this report is threefold. First, we provide a brief outline of the purpose andmore » design of various capacity markets under consideration using variable resource requirement (VRR) demand curves. Second, we discuss some of the main challenges raised in existing literature and a set of interviews that we conducted with market participants, regulators, and observers, including where there substantive differences in opinion. Third, we consider some of the challenges that may be specific to higher penetration levels of VRE. While the well known 'merit order' effect from VRE can be expected to suppress wholesale energy prices and revenue, this may be partly mitigated by increased capacity payments and the greater importance of AS payments for flexible capacity. The potential for greater reliance on capacity markets for generator revenues may amplify any inefficiency and costs associated with capacity price volatility and other suboptimal market design choices. Regulatory intervention to ensure adequate capacity payments and ancillary service revenue may become more prevalent under current market designs as the timescale for market signals shifts increasingly from near term (e.g., day-ahead in wholesale electricity markets) to longer term (annual intervals in capacity markets). Our review and discussion with market participants suggest substantive challenges may remain in implementing capacity markets that provide both adequate operational and investment incentives, particularly under high-VRE scenarios with greater need for flexible capacity.« less

The politics of Piketty: what political science can learn from, and contribute to, the debate on Capital in the twenty-first century.

PubMed

Hopkin, Jonathan

2014-12-01

Thomas Piketty's imposing volume has brought serious economics firmly into the mainstream of public debate on inequality, yet political science has been mostly absent from this debate. This article argues that political science has an essential contribution to make to this debate, and that Piketty's important and powerful book lacks a clear political theory. It develops this argument by first assessing and critiquing the changing nature of political science and its account of contemporary capitalism, and then suggesting how Piketty's thesis can be complemented, extended and challenged by focusing on the ways in which politics and collective action shape the economy and the distribution of income and wealth. Although Capital's principal message is that 'capital is back' and that without political interventions active political interventions will continue to grow, a political economy perspective would suggest another rather more fundamental critique: the very economic forces Piketty describes are embedded in institutional arrangements which can only be properly understood as political phenomena. In a sense capital itself - the central concept of the book - is almost meaningless without proper consideration of its political foundations. Even if the fact of capital accumulation may respond to an economic logic, the process is embedded in a very political logic. The examples of housing policy and the regulation, and failure to regulate, financial markets are used to illustrate these points. © London School of Economics and Political Science 2014.

The policy debate over public investment in comparative effectiveness research.

PubMed

Rich, Eugene C

2009-06-01

Policy makers across the political spectrum, as well as many clinicians and physician professional associations, have proposed that better information on comparative clinical effectiveness should be a key element of any solution to the US health-care cost crisis. This superficial consensus hides intense disagreements over critical issues essential to any new public effort to promote more comparative effectiveness research (CER). This article reviews the background for these disputes, summarizes the different perspectives represented by policy makers and advocates, and offers a framework to aid both practicing and academic internists in understanding the key elements of the emerging debate. Regarding the fundamental question of "what is CER," disagreements rage over whether value or cost effectiveness should be a consideration, and how specific patient perspectives should be reflected in the development and the use of such research. The question of how to pay for CER invokes controversies over the role of the market in producing such information and the private (e.g., insurers and employers) versus public responsibility for its production. The financing debate further highlights the high stakes of comparative effectiveness research, and the risks of stakeholder interests subverting any public process. Accordingly there are a range of proposals for the federal government's role in prioritization, development, and dissemination of CER. The internal medicine community, with its long history of commitment to scientific medical practice and its leadership in evidence-based medicine, should have a strong interest and play an active role in this debate.

Public participation in environmental impact assessment: why, who and how?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Glucker, Anne N., E-mail: anne.glucker@gmx.de; Driessen, Peter P.J., E-mail: p.driessen@uu.nl; Kolhoff, Arend, E-mail: akolhoff@eia.nl

2013-11-15

Even a cursory glance at the literature on environmental impact assessment (EIA) reveals that public participation is being considered as an integral part of the assessment procedure. Public participation in EIA is commonly deemed to foster democratic policy-making and to render EIA more effective. Yet a closer look at the literature unveils that, beyond this general assertion, opinions of the precise meaning, objectives and adequate representation of public participation in EIA considerably diverge. Against this background, in this article we aim to provide a comprehensive overview of the academic debate on public participation in EIA concerning its meaning, objectives andmore » adequate level of inclusiveness. In so doing, we hope to stimulate a more focused debate on the subject, which is key to advancing the research agenda. Furthermore, this paper may serve as a starting point for practitioners involved in defining the role of public participation in EIA practice. -- Highlights: • There is little reflection on the meaning, objectives and adequate level of inclusiveness of public participation in EIA. • We provide a comprehensive overview of the academic debate on public participation in EIA concerning the meaning, objectives and adequate level of inclusiveness. • Theoretical claims put forth by scholars are contrasted with empirical evidence. • Overview shall stimulate a more focused debate on the subject. • This paper may serve as a starting point for practitioners involved in defining the role of public participation in EIA.« less

Yellowstone Wolves and the Forces That Structure Natural Systems

PubMed Central

Dobson, Andy P.

2014-01-01

Since their introduction in 1995 and 1996, wolves have had effects on Yellowstone that ripple across the entire structure of the food web that defines biodiversity in the Northern Rockies ecosystem. Ecological interpretations of the wolves have generated a significant amount of debate about the relative strength of top-down versus bottom-up forces in determining herbivore and vegetation abundance in Yellowstone. Debates such as this are central to the resolution of broader debates about the role of natural enemies and climate as forces that structure food webs and modify ecosystem function. Ecologists need to significantly raise the profile of these discussions; understanding the forces that structure food webs and determine species abundance and the supply of ecosystem services is one of the central scientific questions for this century; its complexity will require new minds, new mathematics, and significant, consistent funding. PMID:25535737

U.S. Experience with the Draft: Learning the Wrong Lessons

DTIC Science & Technology

2013-03-01

W. Laws United States Army Reserve 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND...MSSA) to require the registration and possible conscription of women.15 Considerable public debate took place before Congress decided women would not...concluded “[i]n that event, the hypothetical draft the Court relied on to sustain the MSSA’s gender -based classification would presumably be of little

Mini-conference on helicon plasma sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scime, E. E.; Keesee, A. M.; Boswell, R. W.

2008-05-15

The first two sessions of this mini-conference focused attention on two areas of helicon source research: The conditions for optimal helicon source performance and the origins of energetic electrons and ions in helicon source plasmas. The final mini-conference session reviewed novel applications of helicon sources, such as mixed plasma source systems and toroidal helicon sources. The session format was designed to stimulate debate and discussion, with considerable time available for extended discussion.

CCIR for Complex and Uncertain Environments

DTIC Science & Technology

2007-05-01

these purposes. Doctrine gives such a wide variety of reasons for using CCIR that the concept seems unfocused, giving the commander no true criteria...complex. The true effect that these issues have on CCIR is open to a considerable amount of debate. Every commander has the freedom to develop his...operations. He set a precedent that seems to have held true through the entire history of intelligence requirements – every step in the development

[Technology development as social process: prospects and frontiers of social scientific elucidation of technological advancement].

PubMed

Dierkes, M

1990-05-01

This article provides an overview of the new developments in social scientific technology research which have changed considerably as a result of public debate and reactions to the importance of advancements in technology. The shift in emphasis, away from the effects of technology to its shaping, is described and certain hypotheses and concepts of advancement in the study of the social conditions underlying technical development processes are presented.

Prospective of groundwater overexploitation through participatory approaches: Saiss Plain in Morocco

NASA Astrophysics Data System (ADS)

Ameur, Fatah; Lejars, Caroline; Dionnet, Mathieu; Quarouch, Hassan; Kuper, Marcel

2015-04-01

In the Saiss plain, groundwater overexploitation is often explained by two phenomena. The first one is a natural phenomenon (droughts), which seems therefore uncontrollable; the other one is human as groundwater is largely used by the agricultural sector. The main issue of groundwater governance is to find an acceptable balance in the use of the water resource without compromising the socio-economic development generated by this resource. Our study aims to contribute to understanding the differential contribution of different categories of groundwater users and the socio-economic and agrarian dynamics impacted by the overuse of groundwater. We adopted a participatory approach to explore with the different actors involved in the management and use of groundwater to identify the different viewpoints on the issue of overexploitation and to engage prospective and collective thinking of present situation of groundwater overexploitation. We organized multi-stakeholder workshops and designed a role-playing game to identify and qualify the existing links between the water resource, and the economic and social dynamics in order to better understand the human behavior to economic and environmental crises and the adaptive strategies of farmers confronted with an increasingly scarce groundwater resource. Our results showed considerable differences in the viewpoints of different categories of farmers regarding overexploitation. Agricultural investors who arrived over the past 5 years in the area practicing arboriculture consider themselves modern farmers using precise and water-saving irrigation technologies (drip irrigation, especially) who cannot be blamed for overexploitation of groundwater resources. Lessees practicing horticulture put considerable pressure on water resources, but were not interested in debates on overexploitation and the sustainability of groundwater resources. In fact, they did not turn up for the workshops. Finally, the local small-scale farmers who have very limited access to groundwater due to declining groundwater tables were shown to be the most concerned about groundwater overexploitation, especially the youngsters. These results show that not only different categories of users contribute differently to groundwater overexploitation, but also the direct effects of overexploitation are asymmetrically supported by different categories of users. These results can thus provide the basis for a user-oriented debate on groundwater governance involving the different categories of users and public institutions, by making the differential contribution and impacts of groundwater overexploitation visible. Keywords: Participatory approaches, role-playing game, actors, groundwater, overexploitation, Morocco

Origin of life. The role of experiments, basic beliefs, and social authorities in the controversies about the spontaneous generation of life and the subsequent debates about synthesizing life in the laboratory.

PubMed

Deichmann, Ute

2012-01-01

For centuries the question of the origin of life had focused on the question of the spontaneous generation of life, at least primitive forms of life, from inanimate matter, an idea that had been promoted most prominently by Aristotle. The widespread belief in spontaneous generation, which had been adopted by the Church, too, was finally abandoned at the beginning of the twentieth century, when the question of the origin of life became related to that of the artificial generation of life in the laboratory. This paper examines the role of social authorities, researchers' basic beliefs, crucial experiments, and scientific advance in the controversies about spontaneous generation from the seventeenth to the nineteenth centuries and analyzes the subsequent debates about the synthesis of artificial life in the changing scientific contexts of the nineteenth and early-twentieth centuries. It shows that despite the importance of social authorities, basic beliefs, and crucial experiments scientific advances, especially those in microbiology, were the single most important factor in the stepwise abandoning of the doctrine of spontaneous generation. Research on the origin of life and the artificial synthesis of life became scientifically addressed only when it got rid of the idea of constant smooth transitions between inanimate matter and life and explored possible chemical and physical mechanisms of the specificity of basic molecules and processes of life.

Human cloning, stem cell research. An Islamic perspective.

PubMed

Al-Aqeel, Aida I

2009-12-01

The rapidly changing technologies that involve human subjects raise complex ethical, legal, social, and religious issues. Recent advances in the field of cloning and stem cell research have introduced new hopes for the treatment of serious diseases. But this promise has raised many complex questions. This field causes debate and challenge, not only among scientists but also among ethicists, religious scholars, governments, and politicians. There is no consensus on the morality of human cloning, even within specific religious traditions. In countries in which religion has a strong influence on political decision making, the moral status of the human embryo is at the center of the debate. Because of the inevitable consequences of reproductive cloning, it is prohibited in Islam. However, stem cell research for therapeutic purposes is permissible with full consideration, and all possible precautions in the pre-ensoulment stages of early fetus development, if the source is legitimate.

Internet Addiction: A Brief Summary of Research and Practice

PubMed Central

Cash, Hilarie; Rae, Cosette D; Steel, Ann H; Winkler, Alexander

2012-01-01

Problematic computer use is a growing social issue which is being debated worldwide. Internet Addiction Disorder (IAD) ruins lives by causing neurological complications, psychological disturbances, and social problems. Surveys in the United States and Europe have indicated alarming prevalence rates between 1.5 and 8.2% [1]. There are several reviews addressing the definition, classification, assessment, epidemiology, and co-morbidity of IAD [2-5], and some reviews [6-8] addressing the treatment of IAD. The aim of this paper is to give a preferably brief overview of research on IAD and theoretical considerations from a practical perspective based on years of daily work with clients suffering from Internet addiction. Furthermore, with this paper we intend to bring in practical experience in the debate about the eventual inclusion of IAD in the next version of the Diagnostic and Statistical Manual of Mental Disorders (DSM). PMID:23125561

A code of ethics for health care ethics consultants: journey to the present and implications for the field.

PubMed

Tarzian, Anita J; Wocial, Lucia D

2015-01-01

For decades a debate has played out in the literature about who bioethicists are, what they do, whether they can be considered professionals qua bioethicists, and, if so, what professional responsibilities they are called to uphold. Health care ethics consultants are bioethicists who work in health care settings. They have been seeking guidance documents that speak to their special relationships/duties toward those they serve. By approving a Code of Ethics and Professional Responsibilities for Health Care Ethics Consultants, the American Society for Bioethics and Humanities (ASBH) has moved the professionalization debate forward in a significant way. This first code of ethics focuses on individuals who provide health care ethics consultation (HCEC) in clinical settings. The evolution of the code's development, implications for the field of HCEC and bioethics, and considerations for future directions are presented here.

[I. P. Pavlov and K. Lorenz].

PubMed

Gorokhovskaia, E A

2000-01-01

In the thirtieth, the founder of ethology Austrian zoologist Konrad Lorenz put forward the new theory of behavior, which was met with considerable resistance of the dominant views on the mechanisms of behavior, including Pavlov's concept. From his first theoretical works and later on Lorenz debated with Pavlov. However, these debates were not reduced to a disagreement. He appreciated greatly the scientific contribution of Pavlov, and the ideas of the Russian physiologist were often the starting point of his own speculations. His polemics with Pavlov differed very much from his uncompromising controversies with behaviorists. When Lorenz compared Pavlov's views with behaviorism, he often preferred Pavlov's ideas. Lorenz also draw some parallels between the Pavlov's understanding of behavior and the ethological approach. Lorenz's discussion with Pavlov about the nature of conditioned reflex is of particular interest, since it stimulated Lorenz to develop the theory of this phenomenon.

The ontogenetic origins of mirror neurons: evidence from 'tool-use' and 'audiovisual' mirror neurons.

PubMed

Cook, Richard

2012-10-23

Since their discovery, mirror neurons--units in the macaque brain that discharge both during action observation and execution--have attracted considerable interest. Whether mirror neurons are an innate endowment or acquire their sensorimotor matching properties ontogenetically has been the subject of intense debate. It is widely believed that these units are an innate trait; that we are born with a set of mature mirror neurons because their matching properties conveyed upon our ancestors an evolutionary advantage. However, an alternative view is that mirror neurons acquire their matching properties during ontogeny, through correlated experience of observing and performing actions. The present article re-examines frequently overlooked neurophysiological reports of 'tool-use' and 'audiovisual' mirror neurons within the context of this debate. It is argued that these findings represent compelling evidence that mirror neurons are a product of sensorimotor experience, and not an innate endowment.

Bioethical considerations in translational research: primate stroke.

PubMed

Sughrue, Michael E; Mocco, J; Mack, Willam J; Ducruet, Andrew F; Komotar, Ricardo J; Fischbach, Ruth L; Martin, Thomas E; Connolly, E Sander

2009-05-01

Controversy and activism have long been linked to the subject of primate research. Even in the midst of raging ethical debates surrounding fertility treatments, genetically modified foods and stem-cell research, there has been no reduction in the campaigns of activists worldwide. Playing their trade of intimidation aimed at ending biomedical experimentation in all animals, they have succeeded in creating an environment where research institutions, often painted as guilty until proven innocent, have avoided addressing the issue for fear of becoming targets. One area of intense debate is the use of primates in stroke research. Despite the fact that stroke kills more people each year than AIDS and malaria, and less than 5% of patients are candidates for current therapies, there is significant opposition to primate stroke research. A balanced examination of the ethics of primate stroke research is thus of broad interest to all areas of biomedical research.

Public-private health partnerships: a strategy for WHO.

PubMed Central

Buse, K.; Waxman, A.

2001-01-01

Following early success with a number of high-profile partnerships, WHO is increasingly working with the private for-profit sector. In so doing, the organization finds itself in the maelstrom of a vibrant debate on the roles of public, civic, and commercial entities in society and on the appropriate modes of interaction among them. This paper examines WHO's involvement with the commercial sector, particularly in partnerships. WHO's approach to this sector is outlined and the criticisms levelled at public-private partnerships are reviewed. An indication is given of the steps recently taken by WHO to confront the concerns that have been expressed. The paper argues that partnership between WHO and the commercial sector is inevitable and that it presents considerable opportunities, but also significant risks, for the organization and for public health. A strategy is proposed for directing the debate on issues critical to WHO and its role in the promotion and protection of public health. PMID:11545332

The charisma and deception of reparative therapies: when medical science beds religion.

PubMed

Grace, André P

2008-01-01

In this article, I examine the history and resurgence of interest in sexual reorientation or reparative therapies. I begin with a critique of the contemporary "ex-gay" movement, interrogating Exodus as the prototype of a politico-religious transformational ministry that works to "cure" homosexuals, and examine how Exodus utilizes ex-gay testimony to deceive harried homosexuals looking for escape from the effects of internalized and cultural homophobia. Next, I investigate how reparative therapies function as orthodox treatments that charismatically meld conservative religious perspectives with medical science to produce a pseudoscience promising to treat homosexuality effectively. In this regard, I assess the ongoing debate regarding gay-affirming versus reparative therapies by first looking at the history of medicalizing homosexuality and then surveying the debate spurred by Robert L. Spitzer's research. I conclude with a consideration of research needed to measure whether efficacious change in sexual orientation is possible.

Continuity and change in local immigrant policies in times of austerity.

PubMed

Schiller, Maria; Hackett, Sarah

2018-01-01

European cities are increasingly being recognised for the role they play in devising and implementing their own migration, integration and diversity policies. Yet very little is known about the local dimension of immigrant policymaking in crisis contexts. This introductory piece offers a rationale for analysing city-level immigrant policies in times of crisis and the salience of using crisis as a metaphor for the state of things, and outlines key scholarly works, debates, concepts and theories. It provides a range of historical and contemporary examples and considerations, and introduces an empirical city case study that is published as part of this mini-symposium. It argues that a crisis lens leads to a systematic understanding of local-level immigrant policymaking in recent and contemporary Western Europe. The mini-symposium's focus and findings should be relevant to both on-going academic and policy debates.

The place of care in ethical theory.

PubMed

Veatch, R M

1998-04-01

The concept of care and a related ethical theory of care have emerged as increasingly important in biomedical ethics. This essay outlines a series of questions about the conceptualization of care and its place in ethical theory. First, it considers the possibility that care should be conceptualized as an alternative principle of right action; then as a virtue, a cluster of virtues, or as a synonym for virtue theory. The implications for various interpretations of the debate of the relation of care and justice are then explored, suggesting three possible meanings for that contrast. Next, the possibility that care theorists are taking up the debate over the relation between principles and cases is considered. Finally, it is suggested that care theorists may be pressing for consideration of an entirely new question in moral theory: the assessment of the normative appropriateness of relationships. Issues needing to be addressed in an ethic of relationships are suggested.

Pacemaker implantation rate after transcatheter aortic valve implantation with early and new-generation devices: a systematic review.

PubMed

van Rosendael, Philippe J; Delgado, Victoria; Bax, Jeroen J

2018-06-01

The incidence of new-onset conduction abnormalities requiring permanent pacemaker implantation (PPI) after transcatheter aortic valve implantation (TAVI) with new-generation prostheses remains debated. This systematic review analyses the incidence of PPI after TAVI with new-generation devices and evaluates the electrical, anatomical, and procedural factors associated with PPI. In addition, the incidence of PPI after TAVI with early generation prostheses was reviewed for comparison. According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist, this systematic review screened original articles published between October 2010 and October 2017, reporting on the incidence of PPI after implantation of early and new-generation TAVI prostheses. Of the 1406 original articles identified in the first search for new-generation TAVI devices, 348 articles were examined for full text, and finally, 40 studies (n = 17 139) were included. The incidence of a PPI after the use of a new-generation TAVI prosthesis ranged between 2.3% and 36.1%. For balloon-expandable prostheses, the PPI rate remained low when using an early generation SAPIEN device (ranging between 2.3% and 28.2%), and with the new-generation SAPIEN 3 device, the PPI rate was between 4.0% and 24.0%. For self-expandable prostheses, the PPI rates were higher with the early generation CoreValve device (16.3-37.7%), and despite a reduction in PPI rates with the new Evolut R, the rates remained relatively higher (14.7-26.7%). When dividing the studies according to the highest (>26.0%) and the lowest (<12.1%) quintile of PPI rate, patients within the highest quintile were more frequently women when compared with the lowest quintile group (50.9% vs. 46.3%, P < 0.001). Pre-existent conduction abnormalities (electrical factor), calcification of the left ventricular outflow tract (anatomical factor), and balloon valvuloplasty and depth of implantation (procedural factors) were associated with increased risk of PPI. The rate of PPI after TAVI with new-generation devices is highly variable. Specific recommendations for implantation of each prosthesis, taking into consideration the presence of pre-existent conduction abnormalities and anatomical factors, may be needed to reduce the risk of PPI.

Toward understanding the active SETI debate: Insights from risk communication and perception

NASA Astrophysics Data System (ADS)

Korbitz, Adam

2014-12-01

Insights from the robust field of risk communication and perception have to date been almost totally absent from the policy debate regarding the relative risks and merits of Active SETI or Messaging to Extraterrestrial Intelligence (METI). For many years, the practice (or proposed practice) of Active SETI has generated a vigorous and sometimes heated policy debate within the scientific community. There have also been some negative reactions in the media toward the activities of those engaged in Active SETI. Risk communication is a scientific approach to communication regarding situations involving potentially sensitive or controversial situations in which there may be high public concern and low public trust. The discipline has found wide acceptance and utility in fields such as public health, industrial regulation and environmental protection. Insights from the scientific field of risk communication (such as omission bias, loss aversion, the availability heuristic, probability neglect, and the general human preference for voluntary over involuntary risks) may help those who have participated in either side of the debate over Active SETI to better understand why the debate has taken on this posture. Principles of risk communication and risk perception may also help those engaged in Active SETI to communicate more effectively with other scientists, the public, with the media, and with policy makers regarding their activities and to better understand and respond to concerns expressed regarding the activity.

Unique dielectric dipole and hopping ion dipole relaxation in disordered systems

NASA Astrophysics Data System (ADS)

Govindaraj, G.

2018-04-01

Dielectric or ac conductivity measurements of dielectric and ion conducting glass and crystalline systems provide considerable insight into the nature of the dipolar and ionic motions in disordered solids. However, interpreting the dielectric or ac conductivity has been a matter of considerable debate based on the existing models and empirical formalism, particularly in regards to how best to represent the relaxation process that is the result of a transition from correlated to uncorrelated dipolar and ionic motions. A unique dipole interaction process has been proposed for the (a) dielectric dipole process (b) the hopping ion conducting dipole process and the (c) combination (a) and (b) for the description of dielectric spectra and ac conductivityspectra and results are reported.

To give or sell human gametes--the interplay between pragmatics, policy and ethics.

PubMed

Daniels, K R

2000-06-01

The ever-growing acceptance and use of assisted human reproduction techniques has caused demand for "donated" sperm and eggs to outstrip supply. Medical professionals and others argue that monetary reward is the only way to recruit sufficient numbers of "donors". Is this a clash between pragmatics and policy/ethics? Where monetary payments are the norm, alternative recruitment strategies used successfully elsewhere may not have been considered, nor the negative consequences of commercialism on all participants thought through. Considerations leading some countries to ban the buying and selling of sperm, eggs and embryos are outlined and a case made that the collective welfare of all involved parties be the primary consideration in this, at times heated, debate.

The role of financial wellbeing, sociopolitical attitude, self-interest, and lifestyle in one's attitude toward social health insurance.

PubMed

Schnusenberg, Oliver; Loh, Chung-Ping A; Nihalani, Katrin

2013-08-01

There has been continuous debate in the United States, Germany, and China about their respective healthcare systems. While these three countries are dealing with their own unique problems, the question of how social a healthcare system should be is a topic in this debate. This study examined how strongly college students' attitudes toward a social healthcare system relate to ideological orientation and self-interest. We used samples of college students in the People's Republic of China, Germany, and the US, and extracted factors measuring "financial wellbeing," "sociopolitical attitude," "self-interest," and "lifestyle" to explain the "attitude toward social health insurance" (ASHI) construct developed in recent literature (Loh et al. in Eur J Health Econ 13:707-722). The results of regression analysis showed that sociopolitical attitude/progressivism is positively related to the ASHI, but the degree of association varies considerably from country to country. We also found that a self-interest factor, measured by health status, seems to be inversely related to an individual's ASHI in the US, but not in China or Germany. Individuals with relatively healthy lifestyle choices were less likely to have a favorable ASHI in Germany, but no such relationship was found in China and the US. These results indicate that while some commonalities exist, there are also considerable differences in the structure of ASHI across these three countries. Ultimately, the results reported here could help to develop a predictive model that can be utilized to forecast a country's ASHI. Such a predictive model could be used by politicians to gauge the popularity of a healthcare plan that is under consideration in a particular country.

How Am I Going to Pay for That?!: First-Generation University Students and Their Financial Concerns

ERIC Educational Resources Information Center

Shultz, Judith J. Andrews

2013-01-01

This study examines first-generation research-university students in relation to their financial considerations. It is driven by the question, What is the relationship between first-generation college-student status and financial considerations among research-university students? It explores the impact of such variables as first-generation student…

Evolving minimum standards in responsible international sperm donor offspring quota.

PubMed

Janssens, Pim M W; Thorn, Petra; Castilla, Jose A; Frith, Lucy; Crawshaw, Marilyn; Mochtar, Monique; Bjorndahl, Lars; Kvist, Ulrik; Kirkman-Brown, Jackson C

2015-06-01

An international working group was established with the aim of making recommendations on the number of offspring for a sperm donor that should be allowable in cases of international use of his sperm. Considerations from genetic, psychosocial, operational and ethical points of view were debated. For these considerations, it was assumed that current developments in genetic testing and Internet possibilities mean that, now, all donors are potentially identifiable by their offspring, so no distinction was made between anonymous and non-anonymous donation. Genetic considerations did not lead to restrictive limits (indicating that up to 200 offspring or more per donor may be acceptable except in isolated social-minority situations). Psychosocial considerations on the other hand led to proposals of rather restrictive limits (10 families per donor or less). Operational and ethical considerations did not lead to more or less concrete limits per donor, but seemed to lie in-between those resulting from the aforementioned ways of viewing the issue. In the end, no unifying agreed figure could be reached; however the consensus was that the number should never exceed 100 families. The conclusions of the group are summarized in three recommendations. Copyright © 2015 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

2nd Generation Reusable Launch Vehicle Potential Commercial Development Scenarios

NASA Technical Reports Server (NTRS)

Creech, Stephen D.; Rogacki, John R. (Technical Monitor)

2001-01-01

The presentation will discuss potential commercial development scenarios for a Second Generation Reusable Launch Vehicle. The analysis of potential scenarios will include commercial rates of return, government return on investment, and market considerations. The presentation will include policy considerations in addition to analysis of Second Generation Reusable Launch Vehicle economics. The data discussed is being developed as a part of NASA's Second Generation Reusable Launch Vehicle Program, for consideration as potential scenarios for enabling a next generation system. Material will include potential scenarios not previously considered by NASA or presented at other conferences. Candidate paper has not been presented at a previous meeting, and conference attendance of the author has been approved by NASA.

[Preformation and epigenesis in the works of M. Malpighi].

PubMed

Cingoli, Giuliana

2007-01-01

The article analyzes the scientific debate arosen between Marcello Malpighi and Giovan Battista Trionfetti about the possibility of 'preformation' in plants and living organisms, the existence of spontaneous generation and the meaning and usefullness of particular structures in plants, as 'folia seminalia'.

Early Childhood Discipline: A Review of the Literature

ERIC Educational Resources Information Center

Firmin, Michael W.; Castle, Sally L.

2008-01-01

In this literature review concerning early childhood discipline we particularly highlight American children's discipline with respect to historical perspectives, generational theories, gender issues, parental styles, methods of discipline, and corporal punishment. We also address corporal punishment's history, the debate among experts, beliefs and…

Note: Is it symmetric or not?

PubMed

Stanton, John F

2013-07-28

The reasons by which a molecule might distort from an idealized high symmetry configuration (for example, D3h for the nitrate radical) in a quantum-chemical computation are well-known, but briefly reviewed here in light of considerable recent debate on the BNB molecule. The role of the pseudo-Jahn-Teller effect in such cases is emphasized, as is the ultimate relevance and proper interpretation of the title question in cases where the adiabatic potential energy surface is extremely flat.

Strategic Analysis of the War on Drugs

DTIC Science & Technology

1991-04-09

of the 1960s the drug culture had expanded considerably in the arts and entertainment industries, to college campuses, and to the young in general...At that time, the principal drug of choice was marihuana and to a lesser degree cocaine. 3 Debate over the benign nature of cocaine again surfaced in...widespread use. At least as strong a case could be made for legalizing it as for legalizing marihuana . Short acting--about 15 minutes--not physically

Rights

PubMed Central

Paul, Moli

2007-01-01

This article provides an overview of different types of rights to aid consideration of, and debate about, children and young people's rights in the context of paediatrics and child health. It demonstrates how children's rights may or may not differ from adult rights and the implications for practice. It shows that applying a children's rights framework can be more helpful in pursuing a public child health agenda than in reducing ethical or legal conflicts when interacting with child patients and their families. PMID:17642486

Abolish the Office of the Secretary of Defense?

DTIC Science & Technology

2007-01-01

should he go, the debate should have been whether we even need the Office of the Secretary of Defense (OSD). It is perhaps time to admit that the great...source is the office itself. Simply put, the Secretary of Defense and his supporting staff are too powerful. The wisdom of the creation and relevance of...the original organization are what need to be reconsidered. The following recommendations are offered for consideration. First, abolish the Office of

Autism beyond pediatrics: why bioethicists ought to rethink consent in light of chronicity and genetic identity.

PubMed

Perry, Alexandra

2012-06-01

Autism is a chronic neurodevelopmental disorder that presents unique challenges to bioethicists. In particular, bioethicists ought to reconsider pediatric consent in light of disparity between beliefs that are held about the disorder by parents and adults with autism. The neurodiverse community ought to be given some consideration in this debate, and, as such, there may be a role for autistic narratives in clarifying this problem. © 2011 Blackwell Publishing Ltd.

Nonregenerative natural resources in a sustainable system of energy supply.

PubMed

Bradshaw, Alex M; Hamacher, Thomas

2012-03-12

Following the lead of the European Union in introducing binding measures to promote the use of regenerative energy forms, it is not unreasonable to assume that the global demand for combustible raw materials for energy generation will be reduced considerably in the second half of this century. This will not only have a favourable effect on the CO(2) concentration in the atmosphere, but will also help preserve fossil fuels-important as raw materials in the chemical industry-for future generations. Nevertheless, associated with the concomitant massive shift to regenerative energy forms, there will be a strong demand for other exhaustible raw materials, in particular metals, some of which are already regarded as scarce. After reviewing the debate on mineral depletion between "cornucopians" and "pessimists", we discuss the meaning of mineral "scarcity", particularly in the geochemical sense, and mineral "exhaustion". The expected drastic increase in demand for mineral resources caused by demographic and societal pressures, that is, due to the increase in in-use stock, is emphasised. Whilst not discussing the issue of "strong" versus "weak" sustainability in detail, we conclude that regenerative energy systems-like nearly all resource-consuming systems in our society-do not necessarily satisfy generally accepted sustainability criteria. In this regard, we discuss some current examples, namely, lithium and cobalt for batteries, rare earth-based permanent magnets for wind turbines, cadmium and tellurium for solar cells and copper for electrical power distribution. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

How to study improvement interventions: a brief overview of possible study types

PubMed Central

Portela, Margareth Crisóstomo; Pronovost, Peter J; Woodcock, Thomas; Carter, Pam; Dixon-Woods, Mary

2015-01-01

Improvement (defined broadly as purposive efforts to secure positive change) has become an increasingly important activity and field of inquiry within healthcare. This article offers an overview of possible methods for the study of improvement interventions. The choice of available designs is wide, but debates continue about how far improvement efforts can be simultaneously practical (aimed at producing change) and scientific (aimed at producing new knowledge), and whether the distinction between the practical and the scientific is a real and useful one. Quality improvement projects tend to be applied and, in some senses, self-evaluating. They are not necessarily directed at generating new knowledge, but reports of such projects if well conducted and cautious in their inferences may be of considerable value. They can be distinguished heuristically from research studies, which are motivated by and set out explicitly to test a hypothesis, or otherwise generate new knowledge, and from formal evaluations of improvement projects. We discuss variants of trial designs, quasi-experimental designs, systematic reviews, programme evaluations, process evaluations, qualitative studies, and economic evaluations. We note that designs that are better suited to the evaluation of clearly defined and static interventions may be adopted without giving sufficient attention to the challenges associated with the dynamic nature of improvement interventions and their interactions with contextual factors. Reconciling pragmatism and research rigour is highly desirable in the study of improvement. Trade-offs need to be made wisely, taking into account the objectives involved and inferences to be made. PMID:25810415

Republished: How to study improvement interventions: a brief overview of possible study types

PubMed Central

Portela, Margareth Crisóstomo; Pronovost, Peter J; Woodcock, Thomas; Carter, Pam; Dixon-Woods, Mary

2015-01-01

Improvement (defined broadly as purposive efforts to secure positive change) has become an increasingly important activity and field of inquiry within healthcare. This article offers an overview of possible methods for the study of improvement interventions. The choice of available designs is wide, but debates continue about how far improvement efforts can be simultaneously practical (aimed at producing change) and scientific (aimed at producing new knowledge), and whether the distinction between the practical and the scientific is a real and useful one. Quality improvement projects tend to be applied and, in some senses, self-evaluating. They are not necessarily directed at generating new knowledge, but reports of such projects if well conducted and cautious in their inferences may be of considerable value. They can be distinguished heuristically from research studies, which are motivated by and set out explicitly to test a hypothesis, or otherwise generate new knowledge, and from formal evaluations of improvement projects. We discuss variants of trial designs, quasi-experimental designs, systematic reviews, programme evaluations, process evaluations, qualitative studies, and economic evaluations. We note that designs that are better suited to the evaluation of clearly defined and static interventions may be adopted without giving sufficient attention to the challenges associated with the dynamic nature of improvement interventions and their interactions with contextual factors. Reconciling pragmatism and research rigour is highly desirable in the study of improvement. Trade-offs need to be made wisely, taking into account the objectives involved and inferences to be made. PMID:26045562

Contrasts and synergies in different biofuel reports.

PubMed

Michalopoulos, A; Landeweerd, L; Van der Werf-Kulichova, Z; Puylaert, P G B; Osseweijer, P

2011-04-06

The societal debate on biofuels is characterised by increased complexity. This can hinder the effective governance of the field. This paper attempts a quantitative bird's eye meta-analysis of this complexity by mapping different stakeholder perspectives and expected outcomes as seen in the secondary literature on biofuels, along the lines of the People-Planet-Profit framework. Our analysis illustrates the tension between stated and actual drivers of large scale biofuel development, especially for first generation biofuels. Although environmental (Planet) aspects have dominated the biofuel debate, their overall assessment is mostly negative with regard to first generation biofuels. By contrast, economic (Profit) aspects are the only ones that are assessed positively with regard to first generation biofuels. Furthermore, positive and negative assessments of biofuel development are strongly influenced by the differences in focus between different stakeholder clusters. Stakeholders who appear generally supportive to biofuel development (industry) focus relatively more on aspects that are generally assessed as positive (Profit). By contrast, non-supportive stakeholders (NGO's) tend to focus mainly on aspects that are generally assessed as negative (Planet). Moreover, our analysis of reference lists revealed few citations of primary scientific data, and also that intergovernmental organizations produce the most influential publications in the debate. The surprising lack of listed references to scientific (primary) data reveals a need to assess in which arena the transition of scientific data towards secondary publications takes place, and how one can measure its quality. This work should be understood as a first effort to take some control over a complex and contradictory number of publications, and to allow the effective governance of the field through the identification of areas of overlapping consensus and persisting controversy, without reverting to claims on technical detail.

Direct-to-consumer genomics on the scales of autonomy.

PubMed

Vayena, Effy

2015-04-01

Direct-to-consumer (DTC) genetic services have generated enormous controversy from their first emergence. A dramatic recent manifestation of this is the Food and Drug Administration's (FDA) cease and desist order against 23andMe, the leading provider in the market. Critics have argued for the restrictive regulation of such services, and even their prohibition, on the grounds of the harm they pose to consumers. Their advocates, by contrast, defend them as a means of enhancing the autonomy of those same consumers. Autonomy emerges as a key battle-field in this debate, because many of the 'harm' arguments can be interpreted as identifying threats to autonomy. This paper assesses whether DTC genomic services are a threat to, or instead, an enhancement of, personal autonomy. It deploys Joseph Raz's account of personal autonomy, with its emphasis on choice from a range of valuable options. It then seeks to counter claims that DTC genomics threatens autonomy because it involves manipulation in contravention of consumers' independence or because it does not generate valuable options which can be meaningfully engaged with by consumers. It is stressed that the value of the options generated by DTC genomics should not be judged exclusively from the perspective of medical actionability, but should take into consideration plural utilities. Finally, the paper ends by broaching policy recommendations, suggesting that there is a strong autonomy-based argument for permitting DTC genomic services, and that the key question is the nature of the regulatory conditions under which they should be permitted. The discussion of autonomy in this paper helps illuminate some of these conditions. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Economic and policy implications of the cumulative carbon budget

NASA Astrophysics Data System (ADS)

Allen, M. R.; Otto, F. E. L.; Otto, A.; Hepburn, C.

2014-12-01

The importance of cumulative carbon emissions in determining long-term risks of climate change presents considerable challenges to policy makers. The traditional notion of "total CO2-equivalent emissions", which forms the backbone of agreements such as the Kyoto Protocol and the European Emissions Trading System, is fundamentally flawed. Measures to reduce short-lived climate pollutants benefit the current generation, while measures to reduce long-lived climate pollutants benefit future generations, so there is no sense in which they can ever be considered equivalent. Debates over the correct metric used to compute CO2-equivalence are thus entirely moot: both long-lived and short-lived emissions will need to be addressed if all generations are to be protected from dangerous climate change. As far as long-lived climate pollutants are concerned, the latest IPCC report highlights the overwhelming importance of carbon capture and storage in determining the cost of meeting the goal of limiting anthropogenic warming to two degrees. We will show that this importance arises directly from the cumulative carbon budget and the role of CCS as the technology of last resort before economic activity needs to be restricted to meet ambitious climate targets. It highlights the need to increase the rate of CCS deployment by orders of magnitude if the option of avoiding two degrees is to be retained. The difficulty of achieving this speed of deployment through conventional incentives and carbon-pricing mechanisms suggests a need for a much more direct mandatory approach. Despite their theoretical economic inefficiency, the success of recent regulatory measures in achieving greenhouse gas emissions reductions in jurisdictions such as the United States suggests an extension of the regulatory approach could be a more effective and politically acceptable means of achieving adequately rapid CCS deployment than conventional carbon taxes or cap-and-trade systems.

Color synesthesia. Insight into perception, emotion, and consciousness

PubMed Central

Safran, Avinoam B.; Sanda, Nicolae

2015-01-01

Purpose of review Synesthesia is an extraordinary perceptual phenomenon, in which individuals experience unusual percepts elicited by the activation of an unrelated sensory modality or by a cognitive process. Emotional reactions are commonly associated. The condition prompted philosophical debates on the nature of perception and impacted the course of art history. It recently generated a considerable interest among neuroscientists, but its clinical significance apparently remains underevaluated. This review focuses on the recent studies regarding variants of color synesthesia, the commonest form of the condition. Recent findings Synesthesia is commonly classified as developmental and acquired. Developmental forms predispose to changes in primary sensory processing and cognitive functions, usually with better performances in certain aspects and worse in others, and to heightened creativity. Acquired forms of synesthesia commonly arise from drug ingestion or neurological disorders, including thalamic lesions and sensory deprivation (e.g., blindness). Cerebral exploration using structural and functional imaging has demonstrated distinct patterns in cortical activation and brain connectivity for controls and synesthetes. Artworks of affected painters are most illustrative of the nature of synesthetic experiences. Summary Results of the recent investigations on synesthesia offered a remarkable insight into the mechanisms of perception, emotion and consciousness, and deserve attention both from neuroscientists and from clinicians. PMID:25545055

Color synesthesia. Insight into perception, emotion, and consciousness.

PubMed

Safran, Avinoam B; Sanda, Nicolae

2015-02-01

Synesthesia is an extraordinary perceptual phenomenon, in which individuals experience unusual percepts elicited by the activation of an unrelated sensory modality or by a cognitive process. Emotional reactions are commonly associated. The condition prompted philosophical debates on the nature of perception and impacted the course of art history. It recently generated a considerable interest among neuroscientists, but its clinical significance apparently remains underevaluated. This review focuses on the recent studies regarding variants of color synesthesia, the commonest form of the condition. Synesthesia is commonly classified as developmental and acquired. Developmental forms predispose to changes in primary sensory processing and cognitive functions, usually with better performances in certain aspects and worse in others, and to heightened creativity. Acquired forms of synesthesia commonly arise from drug ingestion or neurological disorders, including thalamic lesions and sensory deprivation (e.g., blindness). Cerebral exploration using structural and functional imaging has demonstrated distinct patterns in cortical activation and brain connectivity for controls and synesthetes. Artworks of affected painters are most illustrative of the nature of synesthetic experiences. Results of the recent investigations on synesthesia offered a remarkable insight into the mechanisms of perception, emotion and consciousness, and deserve attention both from neuroscientists and from clinicians.

Global Warming: A Reduced Threat?.

NASA Astrophysics Data System (ADS)

Michaels, Patrick J.; Stooksbury, David E.

1992-10-01

One popular and apocalyptic vision of the world influenced by increasing concentrations of infrared-absorbing trace gases is that of ecological disaster brought about by rapidly rising temperatures, sea level, and evaporation rates. This vision developed from a suite of climate models that have since considerably changed in both their dynamics and their estimates of prospective warming. Observed temperatures indicate that much more warming should already have taken place than predicted by earlier models in the Northern Hemisphere, and that night, rather than day, readings in that hemisphere show a relative warming. A high-latitude polar-night warming or a general night warming could be either benign or beneficial. A large number of plant species show both increased growth and greater water-use efficiency under enhanced carbon dioxide.An extensive body of evidence now indicates that anthropo-generated sulfate emissions are mitigating some of the warming, and that increased cloudiness as a result of these emissions will further enhance night, rather than day, warming. The sulfate emissions, though, are not sufficient to explain all of the night warming. However, the sensitivity of climate to anthropogenerated aerosols, and the general lack of previously predicted warming, could drastically alter the debate on global warming in favor of less expensive policies.

Climate, environmental and socio-economic change: weighing up the balance in vector-borne disease transmission

DOE PAGES

Parham, Paul E.; Waldock, Joanna; Christophides, George K.; ...

2015-02-16

Arguably one of the most important effects of climate change is the potential impact on human health. While this is likely to take many forms, the implications for future transmission of vector-borne diseases (VBDs), given their ongoing contribution to global disease burden, are both extremely important and highly uncertain. In part, this is due not only to data limitations and methodological challenges when integrating climate-driven VBD models and climate change projections, but, perhaps most crucially, the multitude of epidemiological, ecological, and socioeconomic factors that drive VBD transmission, and this complexity has generated considerable debate over the last 10-15 years. Inmore » this article, and Theme Issue, we seek to elucidate current knowledge around this topic, identify key themes and uncertainties, evaluate ongoing challenges and open research questions, and, crucially, offer some solutions for the field moving forwards. Although many of these challenges are ubiquitous across multiple VBDs, more specific issues also arise in different vector-pathogen systems. This Theme Issue seeks to cover both, reflected in the breadth and depth of the topics and VBD-systems considered, itself strongly indicative of the challenging, but necessary, multidisciplinary nature of this research field.« less

Young Dutch people's experiences of trading sex: a qualitative study.

PubMed

van de Walle, Robert; Picavet, Charles; van Berlo, Willy; Verhoeff, Arnoud

2012-01-01

In recent years, the subject of transactional sex among young Dutch people has generated a heated social debate in the Netherlands. However, accurate data on this phenomenon are scarce. This article describes the findings of a qualitative study on young Dutch people's experiences of having sex in return for money or a material reward. Thirty in-depth interviews were conducted with young Dutch men and women aged 14 to 24. Participants came from diverse backgrounds in terms of gender, ethnicity, sexual orientation, and socioeconomic status. Experiences of trading sex differed in terms of the motivation to trade sex, the presence or absence of coercion, and the availability of other options for earning money. Participants' feelings about their experiences varied. For most participants, the sex itself was unpleasant and required considerable emotion management. Still, some felt adequately compensated by the reward or felt trading sex was preferable to other jobs. Gender played an important role, with feelings of disgust or shame reported especially by female participants, whereas male participants reported more positive experiences. Interactions involving coercion or financial dependence on trading sex generally had a negative emotional impact. Participants stressed the differences between their own experiences and professional prostitution.

Influenza vaccination recommended for all adults aged between 50 and 64 years: conceptual basis and methodological limitations.

PubMed

Manzoli, L; De Vito, C; Flacco, M E; Marzuillo, C; Boccia, A; Villari, P

2012-01-01

In the first half of this year the experts of the Italian Society of Hygiene (SItI), along with those of other National Scientific Societies, agreed with the recommendations made by the USA CDC in 2009, and developed a proposal for a vaccination schedule (Vaccine Schedule for Life), in which influenza vaccination is recommended for all adults aged between 50 and 64 years. In the National Plan for Vaccinal Prevention 2012-2014, which was published just before the issue of the SItI Calendar but concluded earlier (end of 2011), influenza vaccination is recommended "only" for all persons > or = 65 years or included in one of the many at-risk categories. The issue is controversial and has generated considerable debate at national and international level. This short note discusses the logical processes and the scientific evidence in support or against the decision to extend the influenza vaccination. The Authors conclude that the epidemiological approach used by SItI experts is appropriate. In any case, further studies on the topic are strongly needed, and their results should be taken into account in the drafting of future vaccination schedules.

Tissue homeostasis and immunity--more on models.

PubMed

Cunliffe, J

2006-09-01

This article continues the ongoing debate around models of the immune system. Earlier contributors have paid much attention to the various processes that lead to adaptive immune system aggression or tolerance. They have often based their discussions around facts that have been established by experimental investigation. However, both the observation and interpretation of these facts have been influenced by the function--or system goal--that is believed to have generated them. The perception of this function (of all or part of the immune system) is influenced by long established theories in immunology (e.g. horror autotoxicus, clonal deletion in utero, pathogen elimination, clonal selection, auto-immunity and so on) which, for many, have become enshrined as facts. One function that has had less consideration and has not been extensively investigated is the maintenance of tissue homeostasis. When the immune system is viewed from this perspective, the facts invite alternative interpretations. Whilst this perspective may not necessarily be the only valid one, let alone a correct one, viewing things this way--at least briefly--might help to expose hidden assumptions. It also emphasizes that the immune system is a system and, as such, it can by analysed through the principles of general systems theory.

Proposals for DSM-5: introduction to special section of Journal of Personality Disorders.

PubMed

Widiger, Thomas A; Huprich, Steven; Clarkin, John

2011-04-01

On February 10, 2010, the official proposals for the personality disorders section of the fifth edition of the American Psychiatric Association's (APA) Diagnostic and Statistical Manual of Mental Disorders (DSM-5) were posted (see www.dsm5.org ). The posting by the DSM-5 Personality and Personality Disorders Work Group has been helpful in informing the field of the possible changes that may occur with DSM-5. Their presence allows for and encourages persons to provide their suggestions and concerns. The extent of the proposals is considerable. As expressed on the website, "the work group recommends a major reconceptualization of personality psychopathology" (Skodol, 2010, "Reformulation of personality disorders in DSM-5," para. 1). The proposals have generated some controversy. The Journal of Personality Disorders has always sought to be a participant in the crucial debates in our field. The purpose of this special issue is to provide members of the Work Group the opportunity to further articulate the rationale for the proposals, and to provide others an opportunity to articulate their concerns. Copies of this special issue were distributed to interested persons when the complete set of final papers were received (October of 2010).

Oriented Mineral Transformation in a Dark Inclusion from the Leoville Meteorite

NASA Technical Reports Server (NTRS)

Buchanan, P. C.; Zolensky, M. E.; Weisberg, M. K.; Hagiya, K.; Mikouchi, T.; Takenouchi, A.; Hasegawa, H.; Ono, H.; Higashi, K.; Ohsumi, K.

2017-01-01

Dark inclusions (DIs) in chondrites and achondrites are dark gray to black fragments that include a wide variety of materials that have experienced very different petrologic histories. Based on the law of inclusions, they are rocks that accreted prior to and are older than their host meteorites and possibly rep-resent an earlier generation of material. The origin of these inclusions and their relationship to their host meteorites is not always clear. They are interesting in that they represent lithologies that experienced different parent body histories than their host meteorites and are either exotic components or originated from different regions of the meteorite parent body. In many cases, DIs in CV chondrites have been altered to greater degrees than their host meteorites suggesting pre accretionary alteration [e.g., 1,2,3]. There is debate concerning whether or not these DIs record an earlier era of aqueous alteration and subsequent thermal metamorphism, and how these processes may have also affected the host CV materials. The present study is a description of a dark inclusion found in the Leoville meteorite (specifically, thin section USNM 3535-1). This inclusion has some interesting features that have considerable relevance for this discussion.

Evaluating the evidence base for relational frame theory: a citation analysis.

PubMed

Dymond, Simon; May, Richard J; Munnelly, Anita; Hoon, Alice E

2010-01-01

Relational frame theory (RFT) is a contemporary behavior-analytic account of language and cognition. Since it was first outlined in 1985, RFT has generated considerable controversy and debate, and several claims have been made concerning its evidence base. The present study sought to evaluate the evidence base for RFT by undertaking a citation analysis and by categorizing all articles that cited RFT-related search terms. A total of 174 articles were identified between 1991 and 2008, 62 (36%) of which were empirical and 112 (64%) were nonempirical articles. Further analyses revealed that 42 (68%) of the empirical articles were classified as empirical RFT and 20 (32%) as empirical other, whereas 27 (24%) of the nonempirical articles were assigned to the nonempirical reviews category and 85 (76%) to the nonempirical conceptual category. In addition, the present findings show that the majority of empirical research on RFT has been conducted with typically developing adult populations, on the relational frame of sameness, and has tended to be published in either The Psychological Record or the Journal of the Experimental Analysis of Behavior. Overall, RFT has made a substantial contribution to the literature in a relatively short period of time.

Harnessing the uncertainty monster: Putting quantitative constraints on the intergenerational social discount rate

NASA Astrophysics Data System (ADS)

Lewandowsky, Stephan; Freeman, Mark C.; Mann, Michael E.

2017-09-01

There is broad consensus among economists that unmitigated climate change will ultimately have adverse global economic consequences, that the costs of inaction will likely outweigh the cost of taking action, and that social planners should therefore put a price on carbon. However, there is considerable debate and uncertainty about the appropriate value of the social discount rate, that is the extent to which future damages should be discounted relative to mitigation costs incurred now. We briefly review the ethical issues surrounding the social discount rate and then report a simulation experiment that constrains the value of the discount rate by considering 4 sources of uncertainty and ambiguity: Scientific uncertainty about the extent of future warming, social uncertainty about future population and future economic development, political uncertainty about future mitigation trajectories, and ethical ambiguity about how much the welfare of future generations should be valued today. We compute a certainty-equivalent declining discount rate that accommodates all those sources of uncertainty and ambiguity. The forward (instantaneous) discount rate converges to a value near 0% by century's end and the spot (horizon) discount rate drops below 2% by 2100 and drops below previous estimates by 2070.

The metabolic and endocrine response and health implications of consuming sugar-sweetened beverages: findings from recent randomized controlled trials.

PubMed

Rippe, James M

2013-11-01

Fructose-containing sugars, including fructose itself, high fructose corn syrup (HFCS), and sucrose have engendered considerable controversy. The effects of HFCS and sucrose in sugar-sweetened beverages, in particular, have generated intense scientific debate that has spilled over to the public. This controversy is related to well-known differences in metabolism between fructose and glucose in the liver. In addition, research studies have often been conducted comparing pure fructose and pure glucose even though neither is consumed to any appreciable degree in isolation in the human diet. Other evidence has been drawn from animal studies and epidemiologic or cohort studies. Few randomized controlled trials (RCTs) have compared HFCS with sucrose (the 2 sugars most commonly consumed in the human diet) at dosage amounts within the normal human consumption range. This review compares results of recently concluded RCTs with other forms of evidence related to fructose, HFCS, and sucrose. We conclude that great caution must be used when suggesting adverse health effects of consuming these sugars in the normal way they are consumed and at the normal amounts in the human diet, because RCTs do not support adverse health consequences at these doses when employing these sugars.

A case study in evolutionary contingency.

PubMed

Blount, Zachary D

2016-08-01

Biological evolution is a fundamentally historical phenomenon in which intertwined stochastic and deterministic processes shape lineages with long, continuous histories that exist in a changing world that has a history of its own. The degree to which these characteristics render evolution historically contingent, and evolutionary outcomes thereby unpredictably sensitive to history has been the subject of considerable debate in recent decades. Microbial evolution experiments have proven among the most fruitful means of empirically investigating the issue of historical contingency in evolution. One such experiment is the Escherichia coli Long-Term Evolution Experiment (LTEE), in which twelve populations founded from the same clone of E. coli have evolved in parallel under identical conditions. Aerobic growth on citrate (Cit(+)), a novel trait for E. coli, evolved in one of these populations after more than 30,000 generations. Experimental replays of this population's evolution from various points in its history showed that the Cit(+) trait was historically contingent upon earlier mutations that potentiated the trait by rendering it mutationally accessible. Here I review this case of evolutionary contingency and discuss what it implies about the importance of historical contingency arising from the core processes of evolution. Copyright © 2015 Elsevier Ltd. All rights reserved.

Distribution system costs associated with the deployment of photovoltaic systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Horowitz, Kelsey A. W.; Palmintier, Bryan; Mather, Barry

The broadening of our energy system to include increasing amounts of wind and solar has led to significant debate about the total costs and benefits associated with different types of generators - with potentially far-reaching policy implications. This has included debate about the cost associated with integrating these generators onto the electric grid. For photovoltaics (PV), this encompasses costs incurred on both the bulk power and distribution systems, as well as the value provided to them. These costs and benefits, in particular those associated with integrating PV onto the distribution system, are not well understood. We seek to advance themore » state of understanding of 'grid integration costs' for the distribution system by reviewing prior literature and outlining a transparent, bottom-up approach that can be used to calculate these costs. We provide a clear delineation of costs to integrate PV in to the distribution system within the larger context of total costs and benefits associated with PV generators. We emphasize that these costs are situationally dependent, and that a single 'cost of integration' cannot be obtained. We additionally emphasize that benefits must be considered when evaluating the competitiveness of the technology in a given situation.« less

Flow Distribution Control Characteristics in Marine Gas Turbine Waste- Heat Recovery Systems. Phase 2. Flow Distribution Control in Waste-Heat Steam Generators

DTIC Science & Technology

1982-07-01

waste-heat steam generators. The applicable steam generator design concepts and general design consideration were reviewed and critical problems...a once-through forced-circulation steam generator design should be selected because of stability, reliability, compact- ness and lightweight...consists of three sections and one appendix. In Section I, the applicable steam generator design conccpts and general design * considerations are reviewed

The radioactive waste debate in the United States and nuclear technology for peaceful purposes

NASA Astrophysics Data System (ADS)

Tehan, Terrence Norbert

Many ethical, cultural, and economic concerns have accompanied the rapid growth of Western technology. Nuclear technology in particular has experienced considerable opposition because of its perceived dangers, especially disposal of atomic waste. While this field of science remains in its infancy, many legal, political and ecological groups oppose any further application of nuclear technology--including the significant medical, environmental, and economic benefits possible from a safe and responsible application of nuclear energy. Complete and objective knowledge of this technology is needed to balance a healthy respect for the danger of atomic power with its many advantages. This study focuses on one aspect of nuclear technology that has particularly aroused political and social controversy: nuclear waste. Finding ways of disposing safely of nuclear waste has become an extremely volatile issue because of the popular misconception that there is no permanent solution to this problem. This investigation will demonstrate that the supposedly enduring waste problem has been resolved in several industrial countries that now outstrip the United States in safe commercial applications of nuclear science. This dissertation offers a reasoned and objective contribution to the continuing national debate on the peaceful uses of nuclear technology. This debate becomes more crucial as the nation seeks a dependable substitute for the non-renewable sources of energy now rapidly being exhausted.

What is a mental disorder? A perspective from cognitive-affective science.

PubMed

Stein, Dan J

2013-12-01

Defining disease and disorder remains a key conceptual question in philosophy of medicine and psychiatry, and is currently a very practical matter for psychiatric nosology, given the new Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, and the upcoming International Classification of Diseases, 11th Revision. There have been advances in the cognitive-affective science of human categorization, and it is timely to consider implications for our understanding of the category of psychiatric disorder. The category of mental disorder has graded boundaries, and conditions within this category can be conceptualized using MEDICAL or MORAL metaphors. One key set of constructs used in MEDICAL metaphors relates to the notion of dysfunction, and it may, in turn, be useful to conceptualize such dysfunction in evolutionary terms. For typical disorders, it is relatively easy to agree that dysfunction is present. However, for atypical disorders, there may be considerable debate about the presence and extent of dysfunction. Rational arguments can be brought to bear to help decide whether particular entities should be included in our nosologies, and, if so, what their boundaries should be. However, it is appropriate that there should be ongoing debate on diagnostic validity, clinical utility, and other relevant facts and values, for cases that are difficult to decide. The perspective here can be illustrated using many nosological debates within the anxiety disorders and the obsessive-compulsive and related disorders, including the question of delineating normal from abnormal anxiety, of deciding whether anxiety is psychiatric or medical, and the debate about the optimal meta-structure for anxiety disorders.

Review Essay: The Great Debate.

ERIC Educational Resources Information Center

Shah, Amit

1996-01-01

Discusses the following 1995 books on multiculturalism and race relations in the future of American society: "The Next Generation: The New Nationalism and the Fourth American Revolution"; "The End of Racism: Principles for a Multiracial Society"; and "Postethnic America: Beyond Multiculturalism." Perspective positions of the authors are examined…

Debating Values: Race, Class and Academic Achievement

ERIC Educational Resources Information Center

Milton, Penny

2008-01-01

The relationships among race, class and academic achievement are complex, yet have been well documented in Canada for the last thirty years. Generations of students have experienced them--lowered expectations for achievement, gross generalizations about parents' backgrounds and aspirations, negative stereotypes of communities, and curricula that…

Productivity is a poor predictor of plant species richness

USDA-ARS?s Scientific Manuscript database

For 30 years, the relationship between net primary productivity and species richness has generated intense debate in ecology about the processes regulating fine-scale species richness. The true relationship was thought to be hump-shaped, with richness peaking at intermediate levels of productivity, ...

Monitoring and control requirement definition study for Dispersed Storage and Generation (DSG). Volume 5, appendix D: Cost-benefit considerations for providing dispersed storage and generation for electric utilities

NASA Technical Reports Server (NTRS)

1980-01-01

Cost benefit considerations are extremely important in obtaining the acceptance of dispersed storage and generation (DSG) by the electric utilities. These considerations involved somewhat different economic analyses depending on whether the generation is utility, customer, or combined ownership. It is necessary to get acceptance of more easily understood methods for evaluating the economics of DSG because much of the benefits of DSG may accrue in the generation and transmission portions of the utility system while the costs tend to be centered in the distribution portion of that system. The influence of factors, such as reliability, capital costs, and other economic measures were also investigated.

Values and DSM-5: looking at the debate on attenuated psychosis syndrome.

PubMed

Gonçalves, Arthur Maciel Nunes; Dantas, Clarissa de Rosalmeida; Banzato, Claudio E M

2016-01-20

Although values have increasingly received attention in psychiatric literature over the last three decades, their role has been only partially acknowledged in psychiatric classification endeavors. The review process of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) received harsh criticism, and was even considered secretive by some authors. Also, it lacked an official discussion of values at play. In this perspective paper we briefly discuss the interplay of some values in the scientific and non-scientific debate around one of the most debated DSM-5 category proposals, the Attenuated Psychosis Syndrome (APS). Then, we point out some ethical consequences of a facts-plus-values perspective in psychiatric classification. Different stakeholders participated in the APS-debate and for analytical purposes we divided them into four groups: (i) researchers in the field of high-risk mental states; (ii) the DSM-5 Psychotic Disorders Work Group; (iii) patient, carers and advocacy groups; and (iv) external stakeholders, not related to the previous groups, but which also publicly expressed their opinions about APS inclusion in DSM-5. We found that each group differently stressed the role of values we examined in the APS-debate. These values were ethical, but also epistemic, political, economic and ontological. The prominence given to some values, and the lack of discussion about others, generated divergent positions among stakeholders in the debate. As exemplified by the APS discussion, although medicine is primarily an ethical endeavor, values of different kinds that take part in it also shape to a large extent the profession. Thus, it may be strategic to openly discuss values at play in the elaboration of diagnostic tools and classificatory systems. This task, more than scientifically or politically significant, is ethically important.

Carvedilol in the treatment of chronic heart failure: Lessons from The Carvedilol Or Metoprolol European Trial

PubMed Central

Kveiborg, Britt; Major-Petersen, Atheline; Christiansen, Buris; Torp-Pedersen, Christian

2007-01-01

Beta-blockers have been shown to improve survival in patients with chronic heart failure. The effect of different generations of beta blockers has been debated. Both metoprolol and carvedilol have demonstrated beneficial effects in placebo-controlled trials. In The Carvedilol Or Metoprolol European Trial (COMET) two beta blockers were compared in a double-blind randomized matter. This is the first direct comparison between metoprolol and carvedilol of long-term effect on survival in patients with chronic heart failure. The all-cause mortality was signif icantly reduced in the favour of carvedilol. The dose and formulation of metoprolol used in this trial has caused debate, and it has been questioned whether a similar beta1-blockade is obtained in the two intervention groups. At this time there is an unresolved debate as to whether carvedilol is a superior beta-blocker or whether differences in beta1-blockade explained the results of COMET. PMID:17583173

Jump Horse Safety: Reconciling Public Debate and Australian Thoroughbred Jump Racing Data, 2012–2014

PubMed Central

Ruse, Karen; Davison, Aidan; Bridle, Kerry

2015-01-01

Simple Summary This paper documents the dynamics of Australian thoroughbred jump racing in the 2012, 2013, and 2014 seasons with the aim of informing debate about risks to horses and the future of this activity. We conclude that the safety of Australian jump racing has improved in recent years but that steeplechases are considerably riskier for horses than hurdle races. Abstract Thoroughbred jump racing sits in the spotlight of contemporary welfare and ethical debates about horse racing. In Australia, jump racing comprises hurdle and steeplechase races and has ceased in all but two states, Victoria and South Australia. This paper documents the size, geography, composition, and dynamics of Australian jump racing for the 2012, 2013, and 2014 seasons with a focus on debate about risks to horses. We found that the majority of Australian jump racing is regional, based in Victoria, and involves a small group of experienced trainers and jockeys. Australian jump horses are on average 6.4 years of age. The jump career of the majority of horses involves participating in three or less hurdle races and over one season. Almost one quarter of Australian jump horses race only once. There were ten horse fatalities in races over the study period, with an overall fatality rate of 5.1 fatalities per 1000 horses starting in a jump race (0.51%). There was significant disparity between the fatality rate for hurdles, 0.75 fatalities per 1000 starts (0.075%) and steeplechases, 14 fatalities per 1000 starts (1.4%). Safety initiatives introduced by regulators in 2010 appear to have significantly decreased risks to horses in hurdles but have had little or no effect in steeplechases. Our discussion considers these data in light of public controversy, political debate, and industry regulation related to jump horse safety. PMID:26506396

[Medical research-ethics applied to social sciences: relevance, limits, issues and necessary adjustments].

PubMed

Desclaux, A

2008-04-01

Social sciences are concretely concerned by the ethics of medical research when they deal with topics related to health, since they are subjected to clearance procedures specific to this field. This raises at least three questions: - Are principles and practices of medical research ethics and social science research compatible? - Are "research subjects" protected by medical research ethics when they participate in social science research projects? - What can social sciences provide to on-going debates and reflexion in this field? The analysis of the comments coming from ethics committees about social science research projects, and of the experience of implementation of these projects, shows that the application of international ethics standards by institutional review boards or ethics committees raises many problems in particular for researches in ethnology anthropology and sociology. These problems may produce an impoverishment of research, pervert its meaning, even hinder any research. They are not only related to different norms, but also to epistemological divergences. Moreover, in the case of studies in social sciences, the immediate and differed risks, the costs, as well as the benefits for subjects, are very different from those related to medical research. These considerations are presently a matter of debates in several countries such as Canada, Brasil, and USA. From another hand, ethics committees seem to have developed without resorting in any manner to the reflexion carried out within social sciences and more particularly in anthropology Still, the stakes of the ethical debates in anthropology show that many important and relevant issues have been discussed. Considering this debate would provide openings for the reflexion in ethics of health research. Ethnographic studies of medical research ethics principles and practices in various sociocultural contexts may also contribute to the advancement of medical ethics. A "mutual adjustment" between ethics of medical research and social sciences is presently necessary: it raises new questions open for debate.

Tempest in a tea pot: How did the public conversation on genetically modified crops drift so far from the facts?

PubMed

Goldstein, Daniel A

2014-06-01

The debate over genetically modified (GM) crops has raged in Europe since 1996, but had barely risen above a whisper in the USA until recent labeling debates raised public attention. This article will explain GM crops and traits discuss safety assessment provide a view on safety from authoritative organizations discuss selected issues of current debate, and provide the author's perspective as to why the public debate has drifted so far from scientific reality. The economic and environmental benefits of GM crops are beyond scope, but references are provided. GM food and feed undergo comprehensive assessments using recognized approaches to assure they are as safe as the conventional congener. Issues of food safety and nutrition, unrelated to the GM process, may arise when GM foods display novel components or composition. Unanticipated genetic effects in GM crops appear to be limited in contrast to existing variations among conventional varieties resulting from breeding, mutation, and natural mobile genetic elements. Allergenic potential is assessed when selecting genes for introduction into GM crops and remains a theoretical risk to date. Emerging weed and insect resistance is not unique to GM technology and will require the use of integrated pest management/best practices for pest control. Gene flow from GM crops to wild relatives is limited by existing biological barriers but can at time be a relevant consideration in gene selection and planting practices. Insect-resistant GM crops have significantly reduced use of chemical insecticides and appear to have reduced the incidence of pesticide poisoning in areas where small scale farming and hand application are common. Changes in herbicide patterns are more complex and are evolving over time in response to weed resistance management needs. Recent public debate is driven by a combination of unfounded allegations about the technology and purveyors, pseudoscience, and attempts to apply a strict precautionary principle.

[Chakrabarty today: 30 years after the United States Supreme Court Resolution].

PubMed

Bergel, Salvador Darío

2010-01-01

The decision of the United States Supreme Court in the Chakrabarty case marked the beginning of a far reaching process, the development of which considerably extended the field of patentabiltiy of humans, their body parts and genetic information. The author believes that a period of three decades is sufficient to draw conclusions. A critical point has been reached from a debatable decision, which had more economic support than legal, which requires serious recapitulation of the scope and the purpose of industrial property rights.

What price glory: paid/volunteer? Managers debate the problem.

PubMed

Rosenfeld, J

1983-09-01

There are many ways of being "paid" for a job well done. Money, however, is acknowledged by our society as the primary, and in many cases only, appropriate form of compensation. Yet many hospital gift shop managers are not paid wages, though they may be producing hundreds of thousands of dollars in sales each year. It's a retailing phenomenon, and worthy of the discussion which follows between managers who are paid with money and those who choose to accept other considerations as payment in full.

Can chance cause cancer? A causal consideration.

PubMed

Stensrud, Mats Julius; Strohmaier, Susanne; Valberg, Morten; Aalen, Odd Olai

2017-04-01

The role of randomness, environment and genetics in cancer development is debated. We approach the discussion by using the potential outcomes framework for causal inference. By briefly considering the underlying assumptions, we suggest that the antagonising views arise due to estimation of substantially different causal effects. These effects may be hard to interpret, and the results cannot be immediately compared. Indeed, it is not clear whether it is possible to define a causal effect of chance at all. Copyright © 2017 Elsevier Ltd. All rights reserved.

Do relatives have a right to witness resuscitation?

PubMed

Walker, W M

1999-11-01

A relative's right to witness resuscitation is the subject of considerable discussion and debate. This paper explores the presence of relatives in the resuscitation room from a moral and ethical perspective. The focus of discussion is essentially upon the principle of respect for autonomy vs. what appears to be the counter-argument, benevolent paternalism. It is concluded that recognition of a relative's right to witness resuscitation is dependent upon health care professionals' willingness to promote the principle of respect for autonomy.

Clinical considerations on the posology of direct oral anticoagulants.

PubMed

Sáez-Peñataro, J; Avendaño-Solá, C; González-Juanatey, J R

2016-10-01

The efficacy of dicoumarin anticoagulants has been shown in patients with nonvalvular atrial fibrillation. However, they have drawbacks such as the need to adjust the dosage and the interaction with drugs and food. Direct oral anticoagulants are an effective and safe alternative and have a less complicated clinical management. There is considerable debate on the selection criteria for the posology regimens of direct oral anticoagulants. The differences among them and their administration regimens have raised questions about the clinical, pharmacokinetic and pharmacodynamic selection criteria that support the posology. This review critically analyses the available evidence and its impact on the final selection of the dosage regimen. Copyright © 2016 Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI). All rights reserved.

To give or sell human gametes - the interplay between pragmatics, policy and ethics

PubMed Central

Daniels, K

2000-01-01

The ever-growing acceptance and use of assisted human reproduction techniques has caused demand for "donated" sperm and eggs to outstrip supply. Medical professionals and others argue that monetary reward is the only way to recruit sufficient numbers of "donors". Is this a clash between pragmatics and policy/ethics? Where monetary payments are the norm, alternative recruitment strategies used successfully elsewhere may not have been considered, nor the negative consequences of commercialism on all participants thought through. Considerations leading some countries to ban the buying and selling of sperm, eggs and embryos are outlined and a case made that the collective welfare of all involved parties be the primary consideration in this, at times heated, debate. Key Words: Gametes • gifting • selling • ethics • policy PMID:10860215

Health lifestyle theory and the convergence of agency and structure.

PubMed

Cockerham, William C

2005-03-01

This article utilizes the agency-structure debate as a framework for constructing a health lifestyle theory. No such theory currently exists, yet the need for one is underscored by the fact that many daily lifestyle practices involve considerations of health outcomes. An individualist paradigm has influenced concepts of health lifestyles in several disciplines, but this approach neglects the structural dimensions of such lifestyles and has limited applicability to the empirical world. The direction of this article is to present a theory of health lifestyles that includes considerations of both agency and structure, with an emphasis upon restoring structure to its appropriate position. The article begins by defining agency and structure, followed by presentation of a health lifestyle model and the theoretical and empirical studies that support it.

The laboratory curse: variation in temperature stimulates embryonic development and shortens diapause

USDA-ARS?s Scientific Manuscript database

An ongoing biological debate is the difference in trait expression in continuous versus cycling temperature regimes, but are even daily cycling temperatures sufficient to generate natural expression of traits? We compared embryonic development and the duration of diapause for Mormon cricket eggs in...

The method of generating functions in exact scalar field inflationary cosmology

NASA Astrophysics Data System (ADS)

Chervon, Sergey V.; Fomin, Igor V.; Beesham, Aroonkumar

2018-04-01

The construction of exact solutions in scalar field inflationary cosmology is of growing interest. In this work, we review the results which have been obtained with the help of one of the most effective methods, viz., the method of generating functions for the construction of exact solutions in scalar field cosmology. We also include in the debate the superpotential method, which may be considered as the bridge to the slow roll approximation equations. Based on the review, we suggest a classification for the generating functions, and find a connection for all of them with the superpotential.

The role played by stakeholders in the public debate that brought Italy out of the club of nuclear energy producers.

PubMed

Cantone, Marie Claire; Sturloni, Giancarlo; Brunelli, Giancarlo

2007-10-01

In 1964, Italy was the fourth largest world producer of electricity generated by nuclear reactors, second in Europe only to United Kingdom. In subsequent years, various controversial political events contributed towards drastically slowing down the development of the Italian national nuclear program. The 1986 Chernobyl Nuclear Power Plant accident, which caused a public outcry all over Europe, had particularly serious repercussions in Italy. In a controversial referendum, held in November 1987, Italian citizens voted to repeal three laws promoting the installation of nuclear power plants (NPP) on Italian soil and allowing the National Institute for Electrical Energy (ENEL) to participate in the construction of NPP's abroad. This work analyzes the reasons for that decision and the communication strategies of the stakeholders that took part in the public debate on nuclear energy during the weeks following the Chernobyl accident. Drawing from the methodologies used in media studies, a quantitative and qualitative analysis of two leading Italian newspapers was performed. The results reveal that a variety of stakeholders, upholding different values and interests, took part in the debate. There being no tradition of a public dialogue and participation in Italy, the debate was polarized to a "yes/no choice," which eventually caused Italy to abandon the production of nuclear power for civilian use.

International Perspectives on Early Childhood Curricula

ERIC Educational Resources Information Center

Oberhuemer, Pamela

2005-01-01

The early years of childhood are receiving increased public policy attention in many countries around the world. Debates on providing quality services and ensuring a good foundation for lifelong learning are generating a new interest in curriculum issues. What understandings do we have of young children? How do they access and construct knowledge…

What Is Plan B? Using Foucault's Archaeology to Enhance Policy Analysis

ERIC Educational Resources Information Center

Bourke, Terri; Lidstone, John

2015-01-01

Many governments in Western democracies conduct the work of leading their societies forward through policy generation and implementation. Despite government attempts at extensive negotiation, collaboration and debate, the general populace in these same countries frequently express feelings of disempowerment and undue pressure to be compliant,…

Digital Storytelling

ERIC Educational Resources Information Center

King, Michael D.

2012-01-01

Much current debate in 21st century education centers on the relevance of the humanities because of the emphasis on science, technology, engineering, and math (STEM) disciplines and their role in workforce preparation. For the educators the question becomes, What can the humanities offer students in the 21st century? This is the generation that…

Angels or demons?

PubMed

2008-06-01

A fringe meeting at this year's RCN congress, 'Angels and demons… dignity at the heart of nursing', debated the issue of the media portrayal of nurses. Nurses are often depicted at polarised ends of the continuum and the event generated ideas and discussion about how nurses can influence the media portrayal of the profession.

The Serious Games of Racial Accounting in Schools

ERIC Educational Resources Information Center

Martinez, Martha Irene

2011-01-01

Educational disparities are frequently framed in racial comparisons that are based on data generated by sorting and counting racial subgroups. Our reliance on these data, and the sorting and counting mechanisms entailed therein, is fundamental to debates about racial inequalities. What is largely ignored in achievement gap discourse is how racial…

The Growing Complexity of the Academic Enterprise in Europe: A Panoramic View

ERIC Educational Resources Information Center

Kwiek, Marek

2012-01-01

Factors generating change in European higher education have been multilayered, interrelated and often common throughout the continent. The article, drawing from current research and policy debates, discusses the three issues: marketization, privatization, and the competition for public funding; conflicting demands and the teaching/research divide…

The Road Ahead for State Assessments

ERIC Educational Resources Information Center

Policy Analysis for California Education, PACE (NJ3), 2011

2011-01-01

This report includes three papers that address critical "next generation" issues in assessment policy that can help to guide the choices made about system design: computer adaptive assessments, assessment of English learners and assessing science. None of these topics has received the attention that it deserves in the current debate on assessment…

Student-Facilitators as University Tutors: An Effective Approach to Sustainability Education

ERIC Educational Resources Information Center

Sloan, Thomas; Davila, Federico; Malbon, Eleanor

2013-01-01

Higher education institutions are considered by many to be pivotal in shaping the next generation of thinkers and practitioners required to further work towards addressing the sustainability challenges faced by contemporary societies. The extent to which higher education has embraced this responsibility is debateable. Notwithstanding, this article…

Generating Dynamic Democratic Discussions: An Analysis of Teaching with U.S. Presidential Debates

ERIC Educational Resources Information Center

Levy, Brett L. M.; Collet-Gildard, Lauren; Owenby, Thomas C.

2017-01-01

Researchers have found that when young people participate in discussions of controversial political issues, they often become more politically engaged and informed (Hess, 2009). Nonetheless, some educators avoid fostering such discussions because they can become heated and distract from academic learning (Hess, 2002). Presidential elections,…

Reframing Political Messages: Using a Festival to Reach Young Voters

ERIC Educational Resources Information Center

Howard, Leigh Anne; Posler, Brian D.

2012-01-01

Public institutions of higher education are charged with "preparing the next generation of informed, engaged citizens for our democracy" (American Association of State Colleges and Universities [AASCU] 2003, 1). Many institutions have fulfilled this mandate by becoming educational partners with Debate Watch, a program of the Commission on…

On Generating Knowledge in Service to Society

ERIC Educational Resources Information Center

Schwandt, Thomas A.

2005-01-01

In the US debate over science-based educational research, experimentation is again coming to the fore as ideal for establishing an evidence base of what works in educational interventions thus contributing to the climate of accountability in educational research and practice. Mixed methods research is being positioned in this discussion as a…

Coding Issues in Grounded Theory

ERIC Educational Resources Information Center

Moghaddam, Alireza

2006-01-01

This paper discusses grounded theory as one of the qualitative research designs. It describes how grounded theory generates from data. Three phases of grounded theory--open coding, axial coding, and selective coding--are discussed, along with some of the issues which are the source of debate among grounded theorists, especially between its…

Are Demographics the Nation's Destiny?

ERIC Educational Resources Information Center

Glass, Gene V.

2008-01-01

In this article, the author discusses the demographic trends affecting America's public schools. As an expert on empirical evaluation of education, the author believes the major debates over vouchers, charter schools, bilingual education, and other issues are not really about preparing the next generation to compete with China or India, or about…

The School Research Lead

ERIC Educational Resources Information Center

Bennett, Tom

2015-01-01

The researchED movement has generated a new debate about the role of research in schools. Of course there have always been teachers interested in undertaking research and applying the research findings of others. However, involvement in research has tended to be the personal enthusiasm of the individual teacher rather than a coordinated whole…

The mis-measurement of extreme global poverty: A case study in the Pacific Islands

PubMed Central

Gubhaju, Bina

2015-01-01

Debate over the measurement of global poverty in low- and middle-income countries continues unabated. There is considerable controversy surrounding the ‘dollar a day’ measure used to monitor progress against the Millennium Development Goals. This article shines fresh light on the debate with new empirical analyses of poverty (including child poverty), inequality and deprivation levels in the Pacific island state of Vanuatu. The study focuses not only on economic and monetary metrics and measures, but also the measures of deprivation derived from sociology in relation to shelter, sanitation, water, information, nutrition, health and education. Until recently, there had been few, if any, attempts to study poverty and deprivation disparities among children in this part of the world. Different measures yield strikingly different estimates of poverty. The article, therefore, attempts to situate the study findings in the broader international context of poverty measurement and discusses their implications for future research and the post-2015 development agenda. PMID:26336359

Definition of the rectum and level of the peritoneal reflection - still a matter of debate?

PubMed

Kenig, Jakub; Richter, Piotr

2013-09-01

Pathological lesions of the rectum are common and their management requires detailed knowledge of pelvic anatomy. There has been considerable debate as to the definition of the rectum and the variability of the level of the peritoneal reflection. The lack of a clear consensus was proven in the research by McCullen et al. regarding the current pattern of practice for the investigation of primary rectal cancer by general surgeons. To carry out bibliographic research on the definition of the rectum and level of the peritoneal reflection. A web-based published literature search of PubMed, Ovid Medline, Science Direct and Springer was made. The paper presents the current definitions of proximal and distal margin of the rectum and level of peritoneal reflection based not only on the results of tests on cadavers but also on living humans. The results of tests on living humans allow more accurate qualification of patients for local excision, which is particularly important for patients with colorectal cancer.

Attitudes of oncologists toward euthanasia in Turkey.

PubMed

Mayda, Atilla Senih; Ozkara, Erdem; Corapçioğlu, Funda

2005-09-01

There have been intensive debates about euthanasia and attempts to change laws on euthanasia in all countries. What doctors and particularly oncologists think about euthanasia must be taken into consideration, as their voices are crucial in this dialogue. The aim of this study was to find out how Turkish doctors approach euthanasia in the context of cancer. A questionnaire was used to collect data from 85 oncologists out of a total 800 in active oncology practice. Of the oncologists surveyed, 43.8% did not object to euthanasia. Some 33.7% had been asked to perform euthanasia and 41.5% believed that euthanasia was performed secretly although it is against the law in Turkey. Forty-two doctors (50.6%) noted that they had withdrawn treatment in patients. Doctors who encounter terminally ill patients with cancer should update their knowledge about patients' rights and euthanasia. Doctors, who are often asked to perform euthanasia, especially in the cancer setting, can help to illuminate the debates about euthanasia.

MOVING TO INEQUALITY: NEIGHBORHOOD EFFECTS AND EXPERIMENTS MEET STRUCTURE1

PubMed Central

Sampson, Robert J.

2014-01-01

The Moving to Opportunity (MTO) housing experiment has proven to be an important intervention not just in the lives of the poor, but in social science theories of neighborhood effects. Competing causal claims have been the subject of considerable disagreement, culminating in the debate between Clampet-Lundquist and Massey (2008) and Ludwig et al. (2008). This paper assesses the debate by clarifying analytically distinct questions posed by neighborhood-level theories, reconceptualizing selection bias as a fundamental social process worthy of study in its own right rather than as a statistical nuisance, and reconsidering the scientific method of experimentation, and hence causality, in the social world of the city. I also analyze MTO and independent survey data from Chicago to examine trajectories of residential attainment. Although MTO provides crucial leverage for estimating neighborhood effects on individuals, as proponents rightly claim, I demonstrate the implications imposed by a stratified urban structure and how MTO simultaneously provides a new window on the social reproduction of concentrated inequality. PMID:25360053

Balancing liberation and protection: a moderate approach to adolescent health care decision-making.

PubMed

Piker, Andy

2011-05-01

In this paper I examine the debate between 'protectionists' and 'liberationists' concerning the appropriate role of minors in decision-making about their health care, focusing particularly on disagreements between the two sides regarding adolescents. Protectionists advocate a more traditional, paternalistic approach in which minors have relatively little input into the healthcare decision-making process, and decisions are made for them by parents or other adults, guided by a commitment to the patient's best interests. Liberationists, on the other hand, argue in favour of expanded participation by minors in treatment decisions, and decision-making authority for at least some adolescents. My examination of the debate includes discussion of liberationist shifts that have taken place in the medical community as well as in legal policy and practice, and consideration of recent research on adolescent development. In the final section of the paper, I propose a moderate position that addresses both liberationist and protectionist concerns. © 2009 Blackwell Publishing Ltd.

The Inevitability of Assessing Reasons in Debates about Conscientious Objection in Medicine.

PubMed

Card, Robert F

2017-01-01

This article first critically reviews the major philosophical positions in the literature on conscientious objection and finds that they possess significant flaws. A substantial number of these problems stem from the fact that these views fail to assess the reasons offered by medical professionals in support of their objections. This observation is used to motivate the reasonability view, one part of which states: A practitioner who lodges a conscientious refusal must publicly state his or her objection as well as the reasoned basis for the objection and have these subjected to critical evaluation before a conscientious exemption can be granted (the reason-giving requirement). It is then argued that when defenders of the other philosophical views attempt to avoid granting an accommodation to spurious objections based on discrimination, empirically mistaken beliefs, or other unjustified biases, they are implicitly committed to the reason-giving requirement. This article concludes that based on these considerations, a reason-giving position such as the reasonability view possesses a decisive advantage in this debate.

Harm reduction at the crossroads: the case of e-cigarettes.

PubMed

Maziak, Wasim

2014-10-01

The recent popularity of electronic (e)-cigarettes and their rapid uptake by youth has ignited the debate about their role as a harm-reduction strategy. Harm reduction in the context of tobacco control contends that in societies that have achieved considerable success in curbing smoking, leaving the remaining hard-to-quit smokers with an abstinence-only option is unfair, especially when less-harmful choices are available. On one side of the debate are those who call for caution in endorsing such products until critical pieces of evidence about their safety and potential become available, whereas the other side argues that waiting until all questions about e-cigarettes are answered is dogma driven. In this piece, I try to discuss the unresolvable contention between harm-reduction goals of offering safer options to smokers, and those of e-cigarette makers of being commercially viable and profitable. Copyright © 2014 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

Unpacking Constructs: A Network Approach for Studying War Exposure, Daily Stressors and Post-Traumatic Stress Disorder

PubMed Central

De Schryver, Maarten; Vindevogel, Sofie; Rasmussen, Andrew E.; Cramer, Angélique O. J.

2015-01-01

Conflict-affected populations are exposed to stressful events during and after war, and it is well established that both take a substantial toll on individuals’ mental health. Exactly how exposure to events during and after war affect mental health is a topic of considerable debate. Various hypotheses have been put forward on the relation between stressful war exposure (SWE), daily stressors (DS) and the development of post-traumatic stress disorder (PTSD). This paper seeks to contribute to this debate by critically reflecting upon conventional modeling approaches and by advancing an alternative model to studying interrelationships between SWE, DS, and PTSD variables. The network model is proposed as an innovative and comprehensive modeling approach in the field of mental health in the context of war. It involves a conceptualization and representation of variables and relationships that better approach reality, hence improving methodological rigor. It also promises utility in programming and delivering mental health support for war-affected populations. PMID:26733901

Transport for language south of the Sylvian fissure: The routes and history of the main tracts and stations in the ventral language network.

PubMed

Bajada, Claude J; Lambon Ralph, Matthew A; Cloutman, Lauren L

2015-08-01

It is now ten years since a 'ventral language pathway' was demonstrated in vivo in the human brain. In the intervening decade, this result has been replicated and expanded to include multiple possible pathways and functions. Despite this considerable level of research interest, age-old debates regarding the origin, course, termination and, indeed, the very existence of the tracts identified still remain. The current review examines four major tracts associated with the ventral 'semantic' language network, with the aim of elucidating and clarifying their structural and functional roles. Historical and modern conceptualisations of the tracts' neuroanatomical origins and terminations will be discussed, and key discrepancies and debates examined. It is argued that much of the controversy regarding the language pathways has resulted from inconsistencies in terminology, and the lack of a white matter 'lingua franca'. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

How state and federal policies as well as advances in genome science contribute to the high cost of cancer drugs.

PubMed

Ramsey, Scott D

2015-04-01

During a time when cancer drug prices are increasing at an unprecedented rate, a debate has emerged as to whether these drugs continue to provide good value. In this article I argue that this debate is irrelevant because under today's highly distorted market, prices will not be set with value considerations in mind. As an alternative, I suggest considering the "value" of three policy changes—Medicare's "average sales price plus 6 percent" payment program, laws that require insurance coverage of all new cancer drugs, and the Affordable Care Act—that are fueling manufacturers' willingness to set higher prices. More important than these issues, however, is the revolution that is occurring in molecular biology and its impact on scientists' ability to detect changes in the cancer genome. The lowered cost of discovery is driving more competitors into the market, which under distorted pricing paradoxically encourages drug makers to charge ever higher prices for their products. Project HOPE—The People-to-People Health Foundation, Inc.

Working towards an international consensus on criteria for assessing internet gaming disorder: a critical commentary on Petry et al. (2014)

PubMed Central

GRIFFITHS, MARK D.; VAN ROOIJ, ANTONIUS J.; KARDEFELT-WINTHER, DANIEL; STARCEVIC, VLADAN; KIRÁLY, ORSOLYA; PALLESEN, STÅLE; MÜLLER, KAI; DREIER, MICHAEL; CARRAS, MICHELLE; PRAUSE, NICOLE; KING, DANIEL L.; ABOUJAOUDE, ELLIAS; KUSS, DARIA J.; PONTES, HALLEY M.; FERNANDEZ, OLATZ LOPEZ; NAGYGYORGY, KATALIN; ACHAB, SOPHIA; BILLIEUX, JOËL; QUANDT, THORSTEN; CARBONELL, XAVIER; FERGUSON, CHRISTOPHER J.; HOFF, RANI A.; DEREVENSKY, JEFFREY; HAAGSMA, MARIA C.; DELFABBRO, PAUL; COULSON, MARK; HUSSAIN, ZAHEER; DEMETROVICS, ZSOLT

2017-01-01

This commentary paper critically discusses the recent debate paper by Petry et al. (2014) that argued there was now an international consensus for assessing Internet Gaming Disorder (IGD). Our collective opinions vary considerably regarding many different aspects of online gaming. However, we contend that the paper by Petry and colleagues does not provide a true and representative international community of researchers in this area. This paper critically discusses and provides commentary on (i) the representativeness of the international group that wrote the ‘consensus’ paper, and (ii) each of the IGD criteria. The paper also includes a brief discussion on initiatives that could be taken to move the field towards consensus. It is hoped that this paper will foster debate in the IGD field and lead to improved theory, better methodologically designed studies, and more robust empirical evidence as regards problematic gaming and its psychosocial consequences and impact. PMID:26669530

The research imperative revisited: considerations for advancing the debate surrounding medical research as moral imperative.

PubMed

Wayne, Katherine; Glass, Kathleen Cranley

2010-01-01

Medical research is frequently regarded as not only laudable, but even obligatory. However, the moral foundation for such an obligation is far from clear. Lively debate concerning the viability of an obligation to conduct and support medical research is transpiring among a small number of scholars speaking from a variety of backgrounds, yet the current discussion is predominantly situated within several discrete academic and professional circles, allowing only sporadic engagement within and between scholarly disciplines and the medical realm. We aim to lay the groundwork for a focused critique of the "research imperative" by examining (1) its commitments within ideologies of science, medicine, and progress: and (2) its normative theoretical underpinnings. Our analysis finds no solid grounding for the research imperative and exposes problems in the attitudes and arguments supporting it. We believe these concerns present compelling reasons for devoting greater critical attention to the research imperative and to the morality of the medical research enterprise as a whole.

Biased but in Doubt: Conflict and Decision Confidence

PubMed Central

De Neys, Wim; Cromheeke, Sofie; Osman, Magda

2011-01-01

Human reasoning is often biased by intuitive heuristics. A central question is whether the bias results from a failure to detect that the intuitions conflict with traditional normative considerations or from a failure to discard the tempting intuitions. The present study addressed this unresolved debate by using people's decision confidence as a nonverbal index of conflict detection. Participants were asked to indicate how confident they were after solving classic base-rate (Experiment 1) and conjunction fallacy (Experiment 2) problems in which a cued intuitive response could be inconsistent or consistent with the traditional correct response. Results indicated that reasoners showed a clear confidence decrease when they gave an intuitive response that conflicted with the normative response. Contrary to popular belief, this establishes that people seem to acknowledge that their intuitive answers are not fully warranted. Experiment 3 established that younger reasoners did not yet show the confidence decrease, which points to the role of improved bias awareness in our reasoning development. Implications for the long standing debate on human rationality are discussed. PMID:21283574

Scientific method discourses in the construction of 'EMF' science: interests, resources and rhetoric in submissions to a public inquiry.

PubMed

Mercer, David

2002-04-01

Since the late 1970s, there has been considerable debate surrounding the question of whether or not exposures to non-ionizing radiation and electric and magnetic fields (EMF), produced by powerlines and electrical and telecommunications technologies, are harmful to health. Whilst there has been some recent evidence of regulatory fatigue, and attempts to enforce closure, the EMF debate nevertheless still continues. This paper will explore the rôle played by competing images of scientific method in the argumentative strategies used by two of the main protagonists in an Australian public inquiry (held in 1990-91) which investigated the EMF issue: 'Inquiry into Community Needs and High Voltage (132kv and above) Transmission Line Development', the so-called Gibbs Inquiry. Apart from documenting some of the epistemologically intricate features of the EMF controversy, the following discussion will also consider the way scientific method discourses can contribute to enhancing the durability of knowledge claims in legal and regulatory settings.

Assessing causality in drug policy analyses: How useful are the Bradford Hill criteria in analysing take-home naloxone programs?

PubMed

Olsen, Anna; McDonald, David; Lenton, Simon; Dietze, Paul M

2018-05-01

The Bradford Hill criteria for assessing causality are useful in assembling evidence, including within complex policy analyses. In this paper, we argue that the implementation of take-home naloxone (THN) programs in Australia and elsewhere reflects sensible, evidence-based public health policy, despite the absence of randomised controlled trials. However, we also acknowledge that the debate around expanding access to THN would benefit from a careful consideration of causal inference and health policy impact of THN program implementation. Given the continued debate around expanding access to THN, and the relatively recent access to new data from implementation studies, two research groups independently conducted Bradford Hill analyses in order to carefully consider causal inference and health policy impact. Hill's criteria offer a useful analytical tool for interpreting current evidence on THN programs and making decisions about the (un)certainty of THN program safety and effectiveness. © 2017 Australasian Professional Society on Alcohol and other Drugs.

Design, economic and system considerations of large wind-driven generators

NASA Technical Reports Server (NTRS)

Jorgensen, G. E.; Lotker, M.; Meier, R. C.; Brierley, D.

1976-01-01

The increased search for alternative energy sources has lead to renewed interest and studies of large wind-driven generators. This paper presents the results and considerations of such an investigation. The paper emphasizes the concept selection of wind-driven generators, system optimization, control system design, safety aspects, economic viability on electric utility systems and potential electric system interfacing problems.

Medicalising short children with growth hormone? Ethical considerations of the underlying sociocultural aspects.

PubMed

Murano, Maria Cristina

2018-06-01

In 2003, the Food and Drug Administration approved the use of growth hormone treatment for idiopathic short stature children, i.e. children shorter than average due to an unknown medical cause. Given the absence of any pathological conditions, this decision has been contested as a case of medicalisation. The aim of this paper is to broaden the debate over the reasons for and against the treatment, to include considerations of the sociocultural phenomenon of the medicalisation of short stature, by means of a critical understanding of the concept of medicalisation. After defining my understanding of medicalisation and describing both the treatment and the condition of idiopathic short stature, I will problematise two fundamental issues: the medical/non-medical distinction and the debate about the goals of medicine. I will analyse them, combining perspectives of bioethics, medical sociology, philosophy of medicine and medical literature, and I will suggest that there are different levels of normativity of medicalisation. Ultimately, this study shows that: (1) the definition of idiopathic short stature, focusing only on actual height measurement, does not provide enough information to assess the need for treatment or not; (2) the analysis of the goals of medicine should be broadened to include justifications for the treatment; (3) the use of growth hormone for idiopathic short stature involves strong interests from different stakeholders. While the treatment might be beneficial for some children, it is necessary to be vigilant about possible misconduct at different levels of medicalisation.

The challenges of caring in a technological environment: critical care nurses' experiences.

PubMed

McGrath, Mary

2008-04-01

This paper presents and discusses the findings from a phenomenological study which illuminated the lived experiences of experienced critical care nurses caring within a technological environment. While nursing practice is interwoven with technology, much of the literature in this area is speculative. Moreover, there is a debate as to whether and how 'high tech' and 'high touch' are reconcilable; this orientation is referred to as the optimism vs. pessimism debate. On a personal level, the motivation for this study came from the author's 13 years' experience in the critical care area. Following ethical approval, 10 experienced nurses from two cardiothoracic critical care units in Ireland participated in the study. A Heideggerian phenomenological methodology was used. Data collection consisted of unstructured interviews. A method of data analysis described by Walters was used. The findings provide research-based evidence to illuminate further the optimistic/pessimistic debate on technology in nursing. While the study demonstrates that the debate is far from resolved, it reveals a new finding: life-saving technology that supports the lives of critically ill patients can bring experienced nurses very close to their patients/families. The three main themes that emerged: 'alien environment', 'pulling together' and 'sharing the journey' were linked by a common thread of caring. Experienced critical care nurses are able to transcend the obtrusive nature of technology to deliver expert caring to their patients. However, the journey to proficiency in technology is very demanding and novice nurses have difficulty in caring with technology. Relevance to clinical practice. It is recommended that more emphasis be placed on supporting, assisting and educating inexperienced nurses in the critical care area and that the use of technology in nursing be given serious consideration.

Integration of targeted health interventions into health systems: a conceptual framework for analysis.

PubMed

Atun, Rifat; de Jongh, Thyra; Secci, Federica; Ohiri, Kelechi; Adeyi, Olusoji

2010-03-01

The benefits of integrating programmes that emphasize specific interventions into health systems to improve health outcomes have been widely debated. This debate has been driven by narrow binary considerations of integrated (horizontal) versus non-integrated (vertical) programmes, and characterized by polarization of views with protagonists for and against integration arguing the relative merits of each approach. The presence of both integrated and non-integrated programmes in many countries suggests benefits to each approach. While the terms 'vertical' and 'integrated' are widely used, they each describe a range of phenomena. In practice the dichotomy between vertical and horizontal is not rigid and the extent of verticality or integration varies between programmes. However, systematic analysis of the relative merits of integration in various contexts and for different interventions is complicated as there is no commonly accepted definition of 'integration'-a term loosely used to describe a variety of organizational arrangements for a range of programmes in different settings. We present an analytical framework which enables deconstruction of the term integration into multiple facets, each corresponding to a critical health system function. Our conceptual framework builds on theoretical propositions and empirical research in innovation studies, and in particular adoption and diffusion of innovations within health systems, and builds on our own earlier empirical research. It brings together the critical elements that affect adoption, diffusion and assimilation of a health intervention, and in doing so enables systematic and holistic exploration of the extent to which different interventions are integrated in varied settings and the reasons for the variation. The conceptual framework and the analytical approach we propose are intended to facilitate analysis in evaluative and formative studies of-and policies on-integration, for use in systematically comparing and contrasting health interventions in a country or in different settings to generate meaningful evidence to inform policy.

The use of methylphenidate among students: the future of enhancement?

PubMed

Outram, Simon M

2010-04-01

During the past few years considerable debate has arisen within academic journals with respect to the use of smart drugs or cognitive enhancement pharmaceuticals. The following paper seeks to examine the foundations of this cognitive enhancement debate using the example of methylphenidate use among college students. The argument taken is that much of the enhancement debate rests upon inflated assumptions about the ability of such drugs to enhance and over-estimations of either the size of the current market for such drugs or the rise in popularity as drugs for enhancing cognitive abilities. This article provides an overview of the empirical evidence that methylphenidate has the ability to significantly improve cognitive abilities in healthy individuals, and examines whether the presumed uptake of the drug is either as socially significant as implied or growing to the extent that it requires urgent regulatory attention. In addition, it reviews the evidence of side-effects for the use of methylphenidate which may be an influential factor in whether an individual decides to use such drugs. The primary conclusions are that neither drug efficacy, nor the benefit-to-risk balance, nor indicators of current or growing demand provide sufficient evidence that methylphenidate is a suitable example of a cognitive enhancer with mass appeal. In light of these empirically based conclusions, the article discusses why methylphenidate might have become seen as a smart drug or cognitive enhancer.

Junior doctors' working hours: perspectives on the reforms.

PubMed

Wilkinson, Carol

2008-06-01

The European Working Time Directive for junior doctors came into force in Britain in August 2004. The reforms themselves have been a long time in development and implementation since the inception and debates regarding the New Deal, to the current formations under health and safety legislation. This study, undertaken within a hospital trust setting in England, provides an insight into the perspectives of doctors, nurses and human resources managers in relation to the European Working Time Directive. Critical consideration is given to the impact of the reforms upon the National Health Service and more specifically to daily working relationships at the point of implementation. The results demonstrate some ambivalence towards the reforms because of the major shift in culture for the professions per se, but also for the future of health-care delivery where there are considerable tensions.

The expression of long-term potentiation: reconciling the preists and the postivists

PubMed Central

MacDougall, Matthew J.; Fine, Alan

2014-01-01

Long-term potentiation (LTP) of excitatory synaptic transmission in the hippocampus has been investigated in great detail over the past 40 years. Where and how LTP is actually expressed, however, remain controversial issues. Considerable evidence has been offered to support both pre- and postsynaptic contributions to LTP expression. Though it is widely held that postsynaptic expression mechanisms are the primary contributors to LTP expression, evidence for that conclusion is amenable to alternative explanations. Here, we briefly review some key contributions to the ‘locus’ debate and describe data that support a dominant role for presynaptic mechanisms. Recognition of the state-dependency of expression mechanisms, and consideration of the consequences of the spatial relationship between postsynaptic glutamate receptors and presynaptic vesicular release sites, lead to a model that may reconcile views from both sides of the synapse. PMID:24298138

Experimental evidence needed to demonstrate inter- and trans-generational effects of ancestral experiences in mammals.

PubMed

Dias, Brian G; Ressler, Kerry J

2014-10-01

Environmental factors routinely influence an organism's biology. The inheritance or transmission of such influences to descendant generations would be an efficient mode of information transfer across generations. The developmental stage at which a specific environment is encountered by the ancestral generation, and the number of generations over which information about that environment is registered, determines an inter- vs. trans-generational effect of ancestral influence. This commentary will outline the distinction between these influences. While seductive in principle, inter- and trans-generational inheritance in mammals is a hotly debated area of research inquiry. We present constructive criticism of such inheritance, and suggest potential experimental avenues for reconciliation. Finally, epigenetic mechanisms present an avenue for gene regulation that is dynamic. We briefly discuss how such malleability affords the potential for a reversal of any detrimental environmental influences that might have adversely impacted ancestral or descendant generations. © 2014 WILEY Periodicals, Inc.

On the nature of bladder sensation: the concept of sensory modulation.

PubMed

De Wachter, S G; Heeringa, R; van Koeveringe, G A; Gillespie, J I

2011-09-01

Going to the toilet is an essential everyday event. Normally, we do not give much thought to the sensations and factors that trigger voiding behavior: we just go. For many people, this apparently simple task is complicated and dominates their life. They have strong sensations and sudden desires to void, often resulting in incontinence. It is therefore important that we understand the origins for this functional change and identify means to alleviate it. Literature survey. A considerable body of work has focused on this problem and ideas and concepts on the nature of bladder sensations are embedded in the literature. In this paper we argue the necessity to return to first principles and a re-examination of the problem. We explore the use of focus groups to identify relevant bladder sensation and what triggers 'bladder' behavior. We argue that there are differences in what can be described as 'introspective bladder sensations' and the sensations reported immediately before a void, 'void sensations'. Finally, we propose an alternative model describing how peripheral information generating 'introspective sensations' and 'void sensations' might be different but interrelated sensations. By exploring such ideas and identifying such complexity it is our intention to stimulate debate and generate further research in the field in order to understand better the physiology of bladder sensation and the pathology of increased urge, frequency and incontinence. Review of the literature on bladder sensation and the established ideas suggests that we might be missing something and the problem of normal and increased sensation and of urgency may be much more complex. Copyright © 2011 Wiley-Liss, Inc.

What are the origins and relevance of spontaneous bladder contractions? ICI-RS 2017.

PubMed

Drake, Marcus J; Fry, Christopher H; Hashitani, Hikaru; Kirschner-Hermanns, Ruth; Rahnama'i, Mohammad S; Speich, John E; Tomoe, Hikaru; Kanai, Anthony J; McCloskey, Karen D

2018-01-23

Storage phase bladder activity is a counter-intuitive observation of spontaneous contractions. They are potentially an intrinsic feature of the smooth muscle, but interstitial cells in the mucosa and the detrusor itself, as well as other muscular elements in the mucosa may substantially influence them. They are identified in several models explaining lower urinary tract dysfunction. A consensus meeting at the International Consultation on Incontinence Research Society (ICI-RS) 2017 congress considered the origins and relevance of spontaneous bladder contractions by debating which cell type(s) modulate bladder spontaneous activity, whether the methodologies are sufficiently robust, and implications for healthy and abnormal lower urinary tract function. The identified research priorities reflect a wide range of unknown aspects. Cellular contributions to spontaneous contractions in detrusor smooth muscle are still uncertain. Accordingly, insight into the cellular physiology of the bladder wall, particularly smooth muscle cells, interstitial cells, and urothelium, remains important. Upstream influences, such as innervation, endocrine, and paracrine factors, are particularly important. The cellular interactions represent the key understanding to derive the integrative physiology of organ function, notably the nature of signalling between mucosa and detrusor layers. Indeed, it is still not clear to what extent spontaneous contractions generated in isolated preparations mirror their normal and pathological counterparts in the intact bladder. Improved models of how spontaneous contractions influence pressure generation and sensory nerve function are also needed. Deriving approaches to robust evaluation of spontaneous contractions and their influences for experimental and clinical use could yield considerable progress in functional urology. © 2018 Wiley Periodicals, Inc.

Proceedings of the Chornobyl phytoremediation and biomass energy conversion workshop (in English;Russian)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hartley, J.; Tokarevsky, V.

1998-06-01

Many concepts, systems, technical approaches, technologies, ideas, agreements, and disagreements were vigorously discussed during the course of the 2-day workshop. The workshop was successful in generating intensive discussions on the merits of the proposed concept that includes removal of radionuclides by plants and trees (phytoremediation) to clean up soil in the Chornobyl Exclusion Zone (CEZ), use of the resultant biomass (plants and trees) to generate electrical power, and incorporation of ash in concrete casks to be used as storage containers in a licensed repository for low-level waste. Twelve years after the Chornobyl Nuclear Power Plant (ChNPP) Unit 4 accident, whichmore » occurred on April 26, 1986, the primary 4radioactive contamination of concern is from radioactive cesium ({sup 137}Cs) and strontium ({sup 90}Sr). The {sup 137}Cs and {sup 90}Sr were widely distributed throughout the CEZ. The attendees from Ukraine, Russia, Belarus, Denmark and the US provided information, discussed and debated the following issues considerably: distribution and characteristics of radionuclides in CEZ; efficacy of using trees and plants to extract radioactive cesium (Cs) and strontium (Sr) from contaminated soil; selection of energy conversion systems and technologies; necessary infrastructure for biomass harvesting, handling, transportation, and energy conversion; radioactive ash and emission management; occupational health and safety concerns for the personnel involved in this work; and economics. The attendees concluded that the overall concept has technical and possibly economic merits. However, many issues (technical, economic, risk) remain to be resolved before a viable commercial-scale implementation could take place.« less

Through the Lens of Figured Worlds: A Heuristic for Productive Collaboration

ERIC Educational Resources Information Center

Martorana, Christine

2017-01-01

Researchers in the field of composition studies have spent a great deal of time, energy, and scholarship proposing and debating strategies for collaborative pedagogy. While these discussions can be generative, many overlook what should have been central all along: the student collaborators. With this in mind, this essay seeks to focus our…

New Model for Recruitment of Foreign Students Sparks Debate

ERIC Educational Resources Information Center

Moser, Kate

2008-01-01

A London-based company with an unusual model for helping colleges recruit international students has generated concern among faculty members as it has begun expanding into the United States. Into University Partnerships has formed joint ventures with five British universities, building centers where foreign students who may not have qualified for…

Productivity is a poor predictor of plant species richness

Treesearch

P.B. Adler; E.T. Borer; H. Hillebrand; Y. Hautier; A. Hector; S. Harpole; L.R. O’Halloran; J.B. Grace; M. Anderson; J.D. Bakker; L.A. Biederman; C.S. Brown; Y.M. Buckley; L.B. Calabrese; C.-J. Chu; E.E. Cleland; S.L. Collins; K.L. Cottingham; M.J. Crawley; E.I. Damschen; K.W. Davies; N.M. DeCrappeo; P.A. Fay; J. Firn; P. Frater; E.I. Gasarch; D.S. Gruner; N. Hagenah; J. Hille Ris Lambers

2011-01-01

For more than 30 years, the relationship between net primary productivity and species richness has generated intense debate in ecology about the processes regulating local diversity. The original view, which is still widely accepted, holds that the relationship is hump-shaped, with richness first rising and then declining with increasing productivity. Although recent...

Perspectives of Physiology as a Discipline from Senior-Level Millennial-Generation Students

ERIC Educational Resources Information Center

Steury, Michael D.; Poteracki, James M.; Kelly, Kevin L.; Wehrwein, Erica A.

2015-01-01

In the last several decades, there has been a shift in the mindset of research structure from classical "systems or integrative biology" to more molecular focused "-omics" study. A recent topic of debate in physiological societies has been whether or not the "-omic" revolution has delivered in its promises in both…

Preconceptions and Misconceptions of Teaching Composition to the Incarcerated.

ERIC Educational Resources Information Center

Spencer, Stephen

The prison college classroom exists in an environment cut off from the outside world, where the debate over the prison classroom's very existence is fueled by public perceptions and media-generated ideas. The violent Lucasville riots in Ohio in 1994 are fresh in the minds of the public, and movies like "Shawshank Redemption" and…

Language Socialization and Interculturality: Address Terms in Intergenerational Talk in Chinese Diasporic Families

ERIC Educational Resources Information Center

Hua, Zhu

2010-01-01

This paper aims to contribute to the current debate on "interculturality" (IC) by investigating the process of language socialization whereby different generations of diasporic families negotiate, construct, and renew their sociocultural values and identities through interaction. Focusing on the use of address terms and "talk about social,…

The Power of the Practical

ERIC Educational Resources Information Center

Hern, Nicola

2013-01-01

Whether it is a rapid-fire Twitter event as part of #ASEchat, or BBC Radio 4's "Inside Science," the discussion of practical work generates powerful debate. While it is right that the best use of practical work is continually discussed, its value in science teaching is without question. The level of discussion is being further heightened…

Data Entry: Towards the Critical Study of Digital Data and Education

ERIC Educational Resources Information Center

Selwyn, Neil

2015-01-01

The generation and processing of data through digital technologies is an integral element of contemporary society, as reflected in recent debates over online data privacy, "Big Data" and the rise of data mining and analytics in business, science and government. This paper outlines the significance of digital data within education,…

Which Came First--The Technology or the Pedagogy?

ERIC Educational Resources Information Center

Schaffhauser, Dian

2009-01-01

Why is a generation of teachers more knowledgeable about technology than any before it arriving in classrooms with little understanding of how to teach with it? It's a debate that, according to Ann Thompson, director of Iowa State University's Center for Technology in Learning and Teaching, has K-12 and higher education engaged in mutual…

The Proposed U.S.-South Korea Free Trade Agreement (KORUS FTA): Provisions and Implications

DTIC Science & Technology

2008-01-22

alliance as a whole. Differences between the White House and the Democratic leadership in the Congress over the implications of the KORUS FTA have...FTA will generate vigorous debate. Differences over the implications of the KORUS FTA between the White House and the Democratic leadership in the

E-Learning: A Movement Coming of Age?

ERIC Educational Resources Information Center

Reindl, Travis

2005-01-01

Few phenomena in recent history have generated investment, debate, and analysis as online/e-learning. Whether by Internet, video network, or other means, online course and program delivery has been heralded--and dismissed--as a vehicle for revolutionizing teaching and learning in higher education. However, after about a decade of start-ups,…

Creating a Past in the Present. Memory, Identity and Teaching in Post-Dictatorship Argentina

ERIC Educational Resources Information Center

Friedrich, Daniel Sergio

2010-01-01

The dissertation concerns the pedagogical discursive practices that, since the end of the last military dictatorship in Argentina, have generated principles about who is the "responsible citizen" and what constitutes democratic conduct. The focusing is on national education laws and congressional debates, textbooks, and public memorial…

Making Observation Count: Key Design Elements for Meaningful Teacher Observation. Policy Brief 13-5

ERIC Educational Resources Information Center

Goldstein, Jennifer

2013-01-01

Teacher evaluation has emerged as a potentially powerful policy lever in state and federal debates about how to improve public education. The role of student test scores and "value-added" measures in teacher evaluation has generated intense public controversy, but other approaches to evaluation including especially classroom observations…

Neuroscience and the Soul: Competing Explanations for the Human Experience

ERIC Educational Resources Information Center

Preston, Jesse Lee; Ritter, Ryan S.; Hepler, Justin

2013-01-01

The development of fMRI techniques has generated a boom of neuroscience research across the psychological sciences, and revealed neural correlates for many psychological phenomena seen as central to the human experience (e.g., morality, agency). Meanwhile, the rise of neuroscience has reignited old debates over mind-body dualism and the soul.…

Student, Teacher, and Administrator Perspectives on Harm: Implications for Implementing Safe and Caring School Initiatives

ERIC Educational Resources Information Center

Vaandering, Dorothy D.

2013-01-01

Creating safe, caring school environments continues to generate ongoing conversation in the media, professional journals, and academic research, especially through the persistent attention given to incidents and impact of bullying on youth. In Canada, several provincial governments have instituted or are debating the implementation of antibullying…

Socio-Scientific Reasoning Influenced by Identities

ERIC Educational Resources Information Center

Simonneaux, Laurence; Simonneaux, Jean

2009-01-01

Based on the comments by Lopez-Facal and Jimenez-Aleixandre, we consider that the cultural identities within Europe interfere with the question of the re-introduction of the Slovenian bear, generating a kind of "discrimination." When the SAQs under debate run against the students' systems of value, it seems that the closer the connection…

Tackling Illiteracy in Year 7 of the Comprehensive School

ERIC Educational Resources Information Center

Mays, Dennis

2012-01-01

Reading standards are regarded by many as the true yardstick by which to measure school effectiveness, and the relative standards achieved by different generations are often debated by adults. Some young people do not perceive reading to be of anything like such importance, however, using digital communication habitually and easily. Each year a…

Evaluating Drugs and Food Additives for Public Use: A Case Studies Approach.

ERIC Educational Resources Information Center

Merritt, Sheridan V.

1980-01-01

Described is a case study used in an introductory college biology course that provides a basis for generating debate on an issue concerning the regulation of controversial food additives and prescription drugs. The case study contained within this article deals with drug screening, specifically with information related to thalidomide. (CS)

Digital Democratic Voices: Intersecting Student Research, Twitter, and Presidential Debates

ERIC Educational Resources Information Center

Tyma, Adam W.; Pickering, Barbara A.

2015-01-01

A common observation on college campuses today is "students do not look up when walking on campus." It is often thought that such attachment to communication devices demonstrates a lack of connection to the "real world." This perspective exemplifies the need for faculty to connect with the "digital generation" and do…

Measuring US pharmaceutical industry R&D spending.

PubMed

Golec, Joseph; Vernon, John

2008-01-01

Government policy debates on pharmaceutical pricing often turn on whether higher drug prices fund greater company-financed R&D spending. In the US, debate breaks down because each side uses a different measure of R&D spending, and the measures are far apart. Government agencies, Congress and consumer groups use government-generated survey data from the National Science Foundation (NSF), and the pharmaceutical industry uses survey data from the Pharmaceutical Research and Manufacturers of America (PhRMA). This issue is also relevant to academic work because some studies use NSF data, and others use PhRMA data. This article illustrates the pros and cons of these survey data series, and offers a more reliable, comprehensive and replicable alternative series, based on Compustat data.

[Trauma and psychosis in german psychiatry - a historical analysis].

PubMed

Kloocke, Ruth; Schmiedebach, Heinz-Peter; Priebe, Stefan

2010-04-01

The paper reports an historical analysis of the debate on trauma and psychosis in German psychiatry. Content analysis of five leading German psychiatric journals between 1889 and 2005. A substantial number of publications until the late 1960s addressed different aspects of potential links between trauma and subsequent psychosis. Papers exclusively focused on traumatic experience in adulthood. Most papers showed a negative attitude towards the idea of traumatic experiences causing psychosis. The debate on psychological trauma and psychosis refers to a long tradition in German psychiatry. Whilst the discussion contributed significantly to concepts and classifications of psychotic illnesses, it did not generate a coherent model for the potential association of trauma and subsequent psychotic disorder. Copyright Georg Thieme Verlag KG Stuttgart . New York.

On different types of dignity in nursing care: a critique of Nordenfelt.

PubMed

Wainwright, Paul; Gallagher, Ann

2008-01-01

Dignity appears to be an important concept in nursing philosophy and more widely in health care policy and provision. Recent events in the UK have generated much interest in the subject. However, there appears to be some confusion about the precise meaning and application of the concept. An influential contribution to the debate has come from Nordenfelt, who, as part of a European project investigating dignity and the care of older people, has proposed a four-part typology of dignity. In this article, we will explore some of the background to the dignity debate in UK nursing and health care, give a brief overview of Nordenfelt's position, offer some criticisms of his work and propose some modifications to his view.

Guilty but good: defending voluntary active euthanasia from a virtue perspective.

PubMed

Begley, Ann Marie

2008-07-01

This article is presented as a defence of voluntary active euthanasia from a virtue perspective and it is written with the objective of generating debate and challenging the assumption that killing is necessarily vicious in all circumstances. Practitioners are often torn between acting from virtue and acting from duty. In the case presented the physician was governed by compassion and this illustrates how good people may have the courage to sacrifice their own security in the interests of virtue. The doctor's action created huge tensions for the nurse, who was governed by the code of conduct and relevant laws. Appraising active euthanasia from a virtue perspective can offer a more compassionate approach to the predicament of practitioners and clients. The tensions arising from the virtue versus rules debate generates irreconcilable difficulties for nurses. A shift towards virtue would help to resolve this problem and support the call for a change in the law. The controversial nature of this position is acknowledged. The argument is put forward on the understanding that many practitioners will not agree with the conclusions reached.

High harmonic generation in rare gas solids

NASA Astrophysics Data System (ADS)

Reis, David

2015-05-01

There has recently been renewed interest in the interaction of strong optical fields with large band-gap solids. The response is known to involve the attosecond dynamics of the electrons and includes the generation of non-perturbative high-order harmonics. However, the detailed mechanism remain a matter of intense debate. Here we report on high harmonic generation in rare gas solids as compared to a dilute gas. The measured spectrum in the solid exhibits a secondary plateau and a subsequent high-energy cut-off that extends well beyond the gas phase, while the ellipticity dependence is simlar to the gas phase and suggests importance of coherent single-site recombination.

Everything you always wanted to hear about rate making but were afraid to ask

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cady, W.A.

1983-08-04

Rate making is a complicated and time-consuming procedure. That it could benefit from judiciously chosen reforms is beyond question. This article covers several major areas of contention within the regulatory arena, all of which have been the subject of considerable debate in recent years. In an effort to find a compromise position between extremes, the author makes three specific suggestions that, if adopted, could enable parties involved to devote their time and resources to more fundamental questions regarding the regulated utility industries. 3 references.

Drones--ethical considerations and medical implications.

PubMed

Pepper, Tom

2012-01-01

Drones enhance military capability and form a potent element of force protection, allowing humans to be removed from hazardous environments and tedious jobs. However, there are moral, legal, and political dangers associated with their use. Although a time may come when it is possible to develop a drone that is able to autonomously and ethically engage a legitimate target with greater reliability than a human, until then military drones demand a crawl-walk-run development methodology, consent by military personnel for weapon use, and continued debate about the complex issues surrounding their deployment.

An argument for human exploration of the moon and Mars.

PubMed

Spudis, P D

1992-01-01

A debate of the merits of human space travel as opposed to robots is presented. While robotic space travel would be considerably less expensive, the author takes the position that there are certain skills and research abilities that only humans possess. Human contributions to past lunar exploration are considered, along with a discussion of the interaction of humans with robotics or other artificial intelligence or computer driven technologies. The author concludes that while robots and machines are tools which should be incorporated into space travel, they are not adequate substitutes for people.

A Meditation in Which Consideration Is Given to the Past and Future Engagement of Social Science Generally and Critical Physical Education and Sports Scholarship in Particular with Various Scientific Debates, Including the So-Called "Obesity Epidemic" and Contemporary Manifestations of Biological Determinism

ERIC Educational Resources Information Center

Gard, Michael

2011-01-01

My purpose in this paper is to consider the relationship between, on the one hand, critical social science and, on the other hand, existing and emerging sciences of the body. Taking my lead from the sociologist, Steve Fuller, I discuss the ways in which some social scientists, both within and outside physical education and sport, have engaged with…

[Ethical considerations about research with women in situations of violence].

PubMed

Rafael, Ricardo de Mattos Russo; Soares de Moura, Anna Tereza Miranda

2013-01-01

This essay aims at reflecting on the ethical and methodological principles involved in research with women in situation of violence. The text raises the discussion of the application of the principles of beneficence and non-maleficence during researches involving this issue, pointing to recommendations towards privacy, autonomy and immediate contributions for volunteers. Then, taking as theoretical reference the principles of justice and equity, the authors propose a debate on methodological aspects involved in protection of respondents, with a view at improving the quality of the data obtained and possible social contributions.

Considerations Regarding Embryo Culture Conditions: From Media to Epigenetics.

PubMed

Simopoulou, Mara; Sfakianoudis, Konstantinos; Rapani, Anna; Giannelou, Polina; Anifandis, George; Bolaris, Stamatis; Pantou, Agni; Lambropoulou, Maria; Pappas, Athanasios; Deligeoroglou, Efthimios; Pantos, Konstantinos; Koutsilieris, Michael

2018-01-01

There are numerous reports on embryo culture media and conditions in the laboratory, as the subject is multifaceted and complex, reflecting the variation in practice. In this scoping review, we attempt to approach the topic of culture media and conditions from the practitioners' perspective aiming to highlight, in a comprehensive fashion, important aspects regarding the options available, introduce points of debate and controversy, while maintaining the viewpoint of the practicing embryologist's concerns. Copyright© 2018, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

[20th century medical debate over venereal disease and prostitution].

PubMed

Lundberg, A

2001-01-01

In the early twentieth century a wider debate took place about how Swedish society was to fight the spread of contagious venereal diseases and in 1910 a government committee had written a law proposal that would dramatically reform these measures previously, Swedish physicians had been united against any measures against these diseases that did not involve the regulation of prostitutes, but this consensus was slowly withering away in the early parts of the century. Female doctors and a younger generation of venereologists was drawing the conclusion that mandatory checks of only one out of two sexes was insufficient. This article reviews the debate regarding the regulation of prostitution that took place between conservative and liberal members in the Swedish Medical Association in 1911. It depicts a fierce discussion between members that still clung to nineteenth-century ideas of women as being prone to prostitution if left idle and unemployed, and liberal members that believed social injustices such as low wages laid behind women's decisions. The study gives an insight into the complexities of building the Swedish welfare state.

Presynaptic Mechanisms of l-DOPA-Induced Dyskinesia: The Findings, the Debate, and the Therapeutic Implications.

PubMed

Cenci, M Angela

2014-01-01

The dopamine (DA) precursor l-DOPA has been the most effective treatment for Parkinson's disease (PD) for over 40 years. However, the response to this treatment changes with disease progression, and most patients develop dyskinesias (abnormal involuntary movements) and motor fluctuations within a few years of l-DOPA therapy. There is wide consensus that these motor complications depend on both pre- and post-synaptic disturbances of nigrostriatal DA transmission. Several presynaptic mechanisms converge to generate large DA swings in the brain concomitant with the peaks-and-troughs of plasma l-DOPA levels, while post-synaptic changes engender abnormal functional responses in dopaminoceptive neurons. While this general picture is well-accepted, the relative contribution of different factors remains a matter of debate. A particularly animated debate has been growing around putative players on the presynaptic side of the cascade. To what extent do presynaptic disturbances in DA transmission depend on deficiency/dysfunction of the DA transporter, aberrant release of DA from serotonin neurons, or gliovascular mechanisms? And does noradrenaline (which is synthetized from DA) play a role? This review article will summarize key findings, controversies, and pending questions regarding the presynaptic mechanisms of l-DOPA-induced dyskinesia. Intriguingly, the debate around these mechanisms has spurred research into previously unexplored facets of brain plasticity that have far-reaching implications to the treatment of neuropsychiatric disease.

Blood Products and the Commodification Debate: The Blurry Concept of Altruism and the 'Implicit Price' of Readily Available Body Parts.

PubMed

Dufner, Annette

2015-12-01

There is a widespread consensus that a commodification of body parts is to be prevented. Numerous policy papers by international organizations extend this view to the blood supply and recommend a system of uncompensated volunteers in this area--often, however, without making the arguments for this view explicit. This situation seems to indicate that a relevant source of justified worry or unease about the blood supply system has to do with the issue of commodification. As a result, the current health minister of Ontario is proposing a ban on compensation even for blood plasma--despite the fact that Canada can only generate 30 % of the plasma needed for fractionation into important plasma protein products and has to purchase the rest abroad. In the following, I am going to suggest a number of alternative perspectives on the debate in order to facilitate a less dogmatic and more differentiated debate about the matter. Especially in light of the often over-simplified notions of altruism and commodification, I conclude that the debate has not conclusively established that it would be morally objectionable to provide blood plasma donors with monetary compensation or with other forms of explicit social recognition as an incentive. This is especially true of donations for fractionation into medicinal products by profit-oriented pharmaceutical companies.