Sample records for genesys simulation model

  1. GENESIS: a hybrid-parallel and multi-scale molecular dynamics simulator with enhanced sampling algorithms for biomolecular and cellular simulations.

    PubMed

    Jung, Jaewoon; Mori, Takaharu; Kobayashi, Chigusa; Matsunaga, Yasuhiro; Yoda, Takao; Feig, Michael; Sugita, Yuji

    2015-07-01

    GENESIS (Generalized-Ensemble Simulation System) is a new software package for molecular dynamics (MD) simulations of macromolecules. It has two MD simulators, called ATDYN and SPDYN. ATDYN is parallelized based on an atomic decomposition algorithm for the simulations of all-atom force-field models as well as coarse-grained Go-like models. SPDYN is highly parallelized based on a domain decomposition scheme, allowing large-scale MD simulations on supercomputers. Hybrid schemes combining OpenMP and MPI are used in both simulators to target modern multicore computer architectures. Key advantages of GENESIS are (1) the highly parallel performance of SPDYN for very large biological systems consisting of more than one million atoms and (2) the availability of various REMD algorithms (T-REMD, REUS, multi-dimensional REMD for both all-atom and Go-like models under the NVT, NPT, NPAT, and NPγT ensembles). The former is achieved by a combination of the midpoint cell method and the efficient three-dimensional Fast Fourier Transform algorithm, where the domain decomposition space is shared in real-space and reciprocal-space calculations. Other features in SPDYN, such as avoiding concurrent memory access, reducing communication times, and usage of parallel input/output files, also contribute to the performance. We show the REMD simulation results of a mixed (POPC/DMPC) lipid bilayer as a real application using GENESIS. GENESIS is released as free software under the GPLv2 licence and can be easily modified for the development of new algorithms and molecular models. WIREs Comput Mol Sci 2015, 5:310-323. doi: 10.1002/wcms.1220.

  2. Python as a federation tool for GENESIS 3.0.

    PubMed

    Cornelis, Hugo; Rodriguez, Armando L; Coop, Allan D; Bower, James M

    2012-01-01

    The GENESIS simulation platform was one of the first broad-scale modeling systems in computational biology to encourage modelers to develop and share model features and components. Supported by a large developer community, it participated in innovative simulator technologies such as benchmarking, parallelization, and declarative model specification and was the first neural simulator to define bindings for the Python scripting language. An important feature of the latest version of GENESIS is that it decomposes into self-contained software components complying with the Computational Biology Initiative federated software architecture. This architecture allows separate scripting bindings to be defined for different necessary components of the simulator, e.g., the mathematical solvers and graphical user interface. Python is a scripting language that provides rich sets of freely available open source libraries. With clean dynamic object-oriented designs, they produce highly readable code and are widely employed in specialized areas of software component integration. We employ a simplified wrapper and interface generator to examine an application programming interface and make it available to a given scripting language. This allows independent software components to be 'glued' together and connected to external libraries and applications from user-defined Python or Perl scripts. We illustrate our approach with three examples of Python scripting. (1) Generate and run a simple single-compartment model neuron connected to a stand-alone mathematical solver. (2) Interface a mathematical solver with GENESIS 3.0 to explore a neuron morphology from either an interactive command-line or graphical user interface. (3) Apply scripting bindings to connect the GENESIS 3.0 simulator to external graphical libraries and an open source three dimensional content creation suite that supports visualization of models based on electron microscopy and their conversion to computational models. Employed in this way, the stand-alone software components of the GENESIS 3.0 simulator provide a framework for progressive federated software development in computational neuroscience.

  3. Python as a Federation Tool for GENESIS 3.0

    PubMed Central

    Cornelis, Hugo; Rodriguez, Armando L.; Coop, Allan D.; Bower, James M.

    2012-01-01

    The GENESIS simulation platform was one of the first broad-scale modeling systems in computational biology to encourage modelers to develop and share model features and components. Supported by a large developer community, it participated in innovative simulator technologies such as benchmarking, parallelization, and declarative model specification and was the first neural simulator to define bindings for the Python scripting language. An important feature of the latest version of GENESIS is that it decomposes into self-contained software components complying with the Computational Biology Initiative federated software architecture. This architecture allows separate scripting bindings to be defined for different necessary components of the simulator, e.g., the mathematical solvers and graphical user interface. Python is a scripting language that provides rich sets of freely available open source libraries. With clean dynamic object-oriented designs, they produce highly readable code and are widely employed in specialized areas of software component integration. We employ a simplified wrapper and interface generator to examine an application programming interface and make it available to a given scripting language. This allows independent software components to be ‘glued’ together and connected to external libraries and applications from user-defined Python or Perl scripts. We illustrate our approach with three examples of Python scripting. (1) Generate and run a simple single-compartment model neuron connected to a stand-alone mathematical solver. (2) Interface a mathematical solver with GENESIS 3.0 to explore a neuron morphology from either an interactive command-line or graphical user interface. (3) Apply scripting bindings to connect the GENESIS 3.0 simulator to external graphical libraries and an open source three dimensional content creation suite that supports visualization of models based on electron microscopy and their conversion to computational models. Employed in this way, the stand-alone software components of the GENESIS 3.0 simulator provide a framework for progressive federated software development in computational neuroscience. PMID:22276101

  4. ENSO Effect on East Asian Tropical Cyclone Landfall via Changes in Tracks and Genesis in a Statistical Model

    NASA Technical Reports Server (NTRS)

    Yonekura, Emmi; Hall, Timothy M.

    2014-01-01

    Improvements on a statistical tropical cyclone (TC) track model in the western North Pacific Ocean are described. The goal of the model is to study the effect of El Nino-Southern Oscillation (ENSO) on East Asian TC landfall. The model is based on the International Best-Track Archive for Climate Stewardship (IBTrACS) database of TC observations for 1945-2007 and employs local regression of TC formation rates and track increments on the Nino-3.4 index and seasonally varying climate parameters. The main improvements are the inclusion of ENSO dependence in the track propagation and accounting for seasonality in both genesis and tracks. A comparison of simulations of the 1945-2007 period with observations concludes that the model updates improve the skill of this model in simulating TCs. Changes in TC genesis and tracks are analyzed separately and cumulatively in simulations of stationary extreme ENSO states. ENSO effects on regional (100-km scale) landfall are attributed to changes in genesis and tracks. The effect of ENSO on genesis is predominantly a shift in genesis location from the southeast in El Nino years to the northwest in La Nina years, resulting in higher landfall rates for the East Asian coast during La Nina. The effect of ENSO on track propagation varies seasonally and spatially. In the peak activity season (July-October), there are significant changes in mean tracks with ENSO. Landfall-rate changes from genesis- and track-ENSO effects in the Philippines cancel out, while coastal segments of Vietnam, China, the Korean Peninsula, and Japan show enhanced La Nina-year increases.

  5. GENESIS: a hybrid-parallel and multi-scale molecular dynamics simulator with enhanced sampling algorithms for biomolecular and cellular simulations

    PubMed Central

    Jung, Jaewoon; Mori, Takaharu; Kobayashi, Chigusa; Matsunaga, Yasuhiro; Yoda, Takao; Feig, Michael; Sugita, Yuji

    2015-01-01

    GENESIS (Generalized-Ensemble Simulation System) is a new software package for molecular dynamics (MD) simulations of macromolecules. It has two MD simulators, called ATDYN and SPDYN. ATDYN is parallelized based on an atomic decomposition algorithm for the simulations of all-atom force-field models as well as coarse-grained Go-like models. SPDYN is highly parallelized based on a domain decomposition scheme, allowing large-scale MD simulations on supercomputers. Hybrid schemes combining OpenMP and MPI are used in both simulators to target modern multicore computer architectures. Key advantages of GENESIS are (1) the highly parallel performance of SPDYN for very large biological systems consisting of more than one million atoms and (2) the availability of various REMD algorithms (T-REMD, REUS, multi-dimensional REMD for both all-atom and Go-like models under the NVT, NPT, NPAT, and NPγT ensembles). The former is achieved by a combination of the midpoint cell method and the efficient three-dimensional Fast Fourier Transform algorithm, where the domain decomposition space is shared in real-space and reciprocal-space calculations. Other features in SPDYN, such as avoiding concurrent memory access, reducing communication times, and usage of parallel input/output files, also contribute to the performance. We show the REMD simulation results of a mixed (POPC/DMPC) lipid bilayer as a real application using GENESIS. GENESIS is released as free software under the GPLv2 licence and can be easily modified for the development of new algorithms and molecular models. WIREs Comput Mol Sci 2015, 5:310–323. doi: 10.1002/wcms.1220 PMID:26753008

  6. Improving Our Understanding of Tropical Cyclone Genesis

    DTIC Science & Technology

    2009-09-30

    increasingly convergent. Figure 3: Model-derived outgoing long-wave radiation (W m−2) image of Typhoon Ketsana 2003 (left) and Typhoon Mawar 2005 (right...the Typhoon Ketsana simulation (left) and Typhoon Mawar simulation (right). Asterisks denote the time of pre-genesis convective bursts in each...5 s−1) for the Typhoon Ketsana simulation (left) and Typhoon Mawar simulation (right). IMPACT/APPLICATIONS A combined observational and numerical

  7. Modeling of unit operating considerations in generating-capacity reliability evaluation. Volume 2. Computer-program documentation. Final report. [GENESIS, OPCON and OPPLAN

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Patton, A.D.; Ayoub, A.K.; Singh, C.

    1982-07-01

    This report describes the structure and operation of prototype computer programs developed for a Monte Carlo simulation model, GENESIS, and for two analytical models, OPCON and OPPLAN. It includes input data requirements and sample test cases.

  8. GENESIS 1.1: A hybrid-parallel molecular dynamics simulator with enhanced sampling algorithms on multiple computational platforms.

    PubMed

    Kobayashi, Chigusa; Jung, Jaewoon; Matsunaga, Yasuhiro; Mori, Takaharu; Ando, Tadashi; Tamura, Koichi; Kamiya, Motoshi; Sugita, Yuji

    2017-09-30

    GENeralized-Ensemble SImulation System (GENESIS) is a software package for molecular dynamics (MD) simulation of biological systems. It is designed to extend limitations in system size and accessible time scale by adopting highly parallelized schemes and enhanced conformational sampling algorithms. In this new version, GENESIS 1.1, new functions and advanced algorithms have been added. The all-atom and coarse-grained potential energy functions used in AMBER and GROMACS packages now become available in addition to CHARMM energy functions. The performance of MD simulations has been greatly improved by further optimization, multiple time-step integration, and hybrid (CPU + GPU) computing. The string method and replica-exchange umbrella sampling with flexible collective variable choice are used for finding the minimum free-energy pathway and obtaining free-energy profiles for conformational changes of a macromolecule. These new features increase the usefulness and power of GENESIS for modeling and simulation in biological research. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  9. Training in Methods in Computational Neuroscience

    DTIC Science & Technology

    1992-08-29

    in Tritonia. Roger Traub Models with realistic neurons , with an emphasis on large-scale modeling of epileptic phenomena in hippocampus. Rodolpho...Cell Model Plan: 1) Convert some of my simulations from NEURON to GENESIS (and thus learn GENESIS). 2) Develop a realistic inhibtory model . 3) Further...General Hospital, MA Course Project: Membrane Properties of a Neostriatal Neuron and Dopamine Modulation The purpose of my project was to model the

  10. Decline and poleward shift in Indian summer monsoon synoptic activity in a warming climate.

    PubMed

    Sandeep, S; Ajayamohan, R S; Boos, William R; Sabin, T P; Praveen, V

    2018-03-13

    Cyclonic atmospheric vortices of varying intensity, collectively known as low-pressure systems (LPS), travel northwest across central India and produce more than half of the precipitation received by that fertile region and its ∼600 million inhabitants. Yet, future changes in LPS activity are poorly understood, due in part to inadequate representation of these storms in current climate models. Using a high-resolution atmospheric general circulation model that realistically simulates the genesis distribution of LPS, here we show that Indian monsoon LPS activity declines about 45% by the late 21st century in simulations of a business-as-usual emission scenario. The distribution of LPS genesis shifts poleward as it weakens, with oceanic genesis decreasing by ∼60% and continental genesis increasing by ∼10%; over land the increase in storm counts is accompanied by a shift toward lower storm wind speeds. The weakening and poleward shift of the genesis distribution in a warmer climate are confirmed and attributed, via a statistical model, to the reduction and poleward shift of low-level absolute vorticity over the monsoon region, which in turn are robust features of most coupled model projections. The poleward shift in LPS activity results in an increased frequency of extreme precipitation events over northern India. Copyright © 2018 the Author(s). Published by PNAS.

  11. Decline and poleward shift in Indian summer monsoon synoptic activity in a warming climate

    PubMed Central

    Boos, William R.; Sabin, T. P.; Praveen, V.

    2018-01-01

    Cyclonic atmospheric vortices of varying intensity, collectively known as low-pressure systems (LPS), travel northwest across central India and produce more than half of the precipitation received by that fertile region and its ∼600 million inhabitants. Yet, future changes in LPS activity are poorly understood, due in part to inadequate representation of these storms in current climate models. Using a high-resolution atmospheric general circulation model that realistically simulates the genesis distribution of LPS, here we show that Indian monsoon LPS activity declines about 45% by the late 21st century in simulations of a business-as-usual emission scenario. The distribution of LPS genesis shifts poleward as it weakens, with oceanic genesis decreasing by ∼60% and continental genesis increasing by ∼10%; over land the increase in storm counts is accompanied by a shift toward lower storm wind speeds. The weakening and poleward shift of the genesis distribution in a warmer climate are confirmed and attributed, via a statistical model, to the reduction and poleward shift of low-level absolute vorticity over the monsoon region, which in turn are robust features of most coupled model projections. The poleward shift in LPS activity results in an increased frequency of extreme precipitation events over northern India. PMID:29483270

  12. Decline and poleward shift in Indian summer monsoon synoptic activity in a warming climate

    NASA Astrophysics Data System (ADS)

    Sandeep, S.; Ajayamohan, R. S.; Boos, William R.; Sabin, T. P.; Praveen, V.

    2018-03-01

    Cyclonic atmospheric vortices of varying intensity, collectively known as low-pressure systems (LPS), travel northwest across central India and produce more than half of the precipitation received by that fertile region and its ˜600 million inhabitants. Yet, future changes in LPS activity are poorly understood, due in part to inadequate representation of these storms in current climate models. Using a high-resolution atmospheric general circulation model that realistically simulates the genesis distribution of LPS, here we show that Indian monsoon LPS activity declines about 45% by the late 21st century in simulations of a business-as-usual emission scenario. The distribution of LPS genesis shifts poleward as it weakens, with oceanic genesis decreasing by ˜60% and continental genesis increasing by ˜10%; over land the increase in storm counts is accompanied by a shift toward lower storm wind speeds. The weakening and poleward shift of the genesis distribution in a warmer climate are confirmed and attributed, via a statistical model, to the reduction and poleward shift of low-level absolute vorticity over the monsoon region, which in turn are robust features of most coupled model projections. The poleward shift in LPS activity results in an increased frequency of extreme precipitation events over northern India.

  13. Potential role of vegetation feedback in the climate sensitivity of high-latitude regions: A case study at 6000 years B.P.

    USGS Publications Warehouse

    Kutzbach, J.-E.; Bartlein, P.J.; Foley, J.A.; Harrison, S.P.; Hosteller, S.W.; Liu, Z.; Prentice, I.C.; Webb, T.

    1996-01-01

    Previous climate model simulations have shown that the configuration of the Earth's orbit during the early to mid-Holocene (approximately 10-5 kyr) can account for the generally warmer-than-present conditions experienced by the high latitudes of the northern hemisphere. New simulations for 6 kyr with two atmospheric/mixed-layer ocean models (Community Climate Model, version 1, CCM1, and Global ENvironmental and Ecological Simulation of Interactive Systems, version 2, GENESIS 2) are presented here and compared with results from two previous simulations with GENESIS 1 that were obtained with and without the albedo feedback due to climate-induced poleward expansion of the boreal forest. The climate model results are summarized in the form of potential vegetation maps obtained with the global BIOME model, which facilitates visual comparisons both among models and with pollen and plant macrofossil data recording shifts of the forest-tundra boundary. A preliminary synthesis shows that the forest limit was shifted 100-200 km north in most sectors. Both CCM1 and GENESIS 2 produced a shift of this magnitude. GENESIS 1 however produced too small a shift, except when the boreal forest albedo feedback was included. The feedback in this case was estimated to have amplified forest expansion by approximately 50%. The forest limit changes also show meridional patterns (greatest expansion in central Siberia and little or none in Alaska and Labrador) which have yet to be reproduced by models. Further progress in understanding of the processes involved in the response of climate and vegetation to orbital forcing will require both the deployment of coupled atmosphere-biosphere-ocean models and the development of more comprehensive observational data sets.

  14. A climatological model of North Indian Ocean tropical cyclone genesis, tracks and landfall

    NASA Astrophysics Data System (ADS)

    Wahiduzzaman, Mohammad; Oliver, Eric C. J.; Wotherspoon, Simon J.; Holbrook, Neil J.

    2017-10-01

    Extensive damage and loss of life can be caused by tropical cyclones (TCs) that make landfall. Modelling of TC landfall probability is beneficial to insurance/re-insurance companies, decision makers, government policy and planning, and residents in coastal areas. In this study, we develop a climatological model of tropical cyclone genesis, tracks and landfall for North Indian Ocean (NIO) rim countries based on kernel density estimation, a generalised additive model (GAM) including an Euler integration step, and landfall detection using a country mask approach. Using a 35-year record (1979-2013) of tropical cyclone track observations from the Joint Typhoon Warning Centre (part of the International Best Track Archive Climate Stewardship Version 6), the GAM is fitted to the observed cyclone track velocities as a smooth function of location in each season. The distribution of cyclone genesis points is approximated by kernel density estimation. The model simulated TCs are randomly selected from the fitted kernel (TC genesis), and the cyclone paths (TC tracks), represented by the GAM together with the application of stochastic innovations at each step, are simulated to generate a suite of NIO rim landfall statistics. Three hindcast validation methods are applied to evaluate the integrity of the model. First, leave-one-out cross validation is applied whereby the country of landfall is determined by the majority vote (considering the location by only highest percentage of landfall) from the simulated tracks. Second, the probability distribution of simulated landfall is evaluated against the observed landfall. Third, the distances between the point of observed landfall and simulated landfall are compared and quantified. Overall, the model shows very good cross-validated hindcast skill of modelled landfalling cyclones against observations in each of the NIO tropical cyclone seasons and for most NIO rim countries, with only a relatively small difference in the percentage of predicted landfall locations compared with observations.

  15. Impact of global warming on tropical cyclone genesis in coupled and forced simulations: role of SST spatial anomalies

    NASA Astrophysics Data System (ADS)

    Royer, Jean-François; Chauvin, Fabrice; Daloz, Anne-Sophie

    2010-05-01

    The response of tropical cyclones (TC) activity to global warming has not yet reached a clear consensus in the Fourth Assessment Report (AR4) published by the Intergovernmental Panel on Climate Change (IPCC, 2007) or in the recent scientific literature. Observed series are neither long nor reliable enough for a statistically significant detection and attribution of past TC trends, and coupled climate models give widely divergent results for the future evolution of TC activity in the different ocean basins. The potential importance of the spatial structure of the future SST warming has been pointed out by Chauvin et al. (2006) in simulations performed at CNRM with the ARPEGE-Climat GCM. The current presentation describes a new set of simulations that have been performed with the ARPEGE-Climat model to try to understand the possible role of SST patterns in the TC cyclogenesis response in 15 CMIP3 coupled simulations analysed by Royer et al (2009). The new simulations have been performed with the atmospheric component of the ARPEGE-Climat GCM forced in 10 year simulations by the SST patterns from each of 15 CMIP3 simulations with different climate model at the end of the 21st century according to scenario A2. The TC analysis is based on the computation of a Convective Yearly Genesis Parameter (CYGP) and the Genesis Potential Index (GPI). The computed genesis indices for each of the ARPEGE-Climat forced simulations is compared with the indices computed directly from the initial coupled simulation. The influence of SST patterns can then be more easily assessed since all the ARPEGE-Climat simulations are performed with the same atmospheric model, whereas the original simulations used models with different parameterization and resolutions. The analysis shows that CYGP or GPI anomalies obtained with ARPEGE are as variable between each other as those obtained originally by the different IPCC models. The variety of SST patterns used to force ARPEGE explains a large part of the dispersion, though for a given SST pattern, ARPEGE does not necessarily reproduce the anomaly produced originally by the IPCC model which produced the SST anomaly. Many factors can contribute to this discrepancy, but the most prominent seems to be the absence of coupling between the forced atmospheric ARPEGE simulation and the underlying ocean. When the atmospheric model is forced by prescribed SST anomalies some retroactions between cyclogenesis and ocean are missing. There are however areas over the globe were models agree about the CYGP or GPI anomalies induced by global warming, such as the Indian Ocean that shows a better coherency in the coupled and forced responses. This could be an indication that interaction between ocean and atmosphere is not as strong there as in the other basins. Details of the results for all the other ocean basins will be presented. References: Chauvin F. and J.-F. Royer and M. Déqué , 2006: Response of hurricane-type vortices to global warming as simulated by ARPEGE-Climat at high resolution. Climate Dynamics 27(4), 377-399. IPCC [Intergovernmental Panel for Climate Change], Climate change 2007: The physical science basis, in: S. Solomon et al. (eds.), Cambridge University Press. Royer JF, F Chauvin, 2009: Response of tropical cyclogenesis to global warming in an IPCC AR-4 scenario assessed by a modified yearly genesis parameter. "Hurricanes and Climate Change", J. B. Elsner and T. H. Jagger (Eds.), Springer, ISBN: 978-0-387-09409-0, pp 213-234.

  16. Predicting Tropical Cyclogenesis with a Global Mesoscale Model: Preliminary Results with Very Severe Cyclonic Storm Nargis (2008)

    NASA Astrophysics Data System (ADS)

    Shen, B.; Tao, W.; Atlas, R.

    2008-12-01

    Very Severe Cyclonic Storm Nargis, the deadliest named tropical cyclone (TC) in the North Indian Ocean Basin, devastated Burma (Myanmar) in May 2008, causing tremendous damage and numerous fatalities. An increased lead time in the prediction of TC Nargis would have increased the warning time and may therefore have saved lives and reduced economic damage. Recent advances in high-resolution global models and supercomputers have shown the potential for improving TC track and intensity forecasts, presumably by improving multi-scale simulations. The key but challenging questions to be answered include: (1) if and how realistic, in terms of timing, location and TC general structure, the global mesoscale model (GMM) can simulate TC genesis and (2) under what conditions can the model extend the lead time of TC genesis forecasts. In this study, we focus on genesis prediction for TCs in the Indian Ocean with the GMM. Preliminary real-data simulations show that the initial formation and intensity variations of TC Nargis can be realistically predicted at a lead time of up to 5 days. These simulations also suggest that the accurate representations of a westerly wind burst (WWB) and an equatorial trough, associated with monsoon circulations and/or a Madden-Julian Oscillation (MJO), are important for predicting the formation of this kind of TC. In addition to the WWB and equatorial trough, other favorable environmental conditions will be examined, which include enhanced monsoonal circulation, upper-level outflow, low- and middle-level moistening, and surface fluxes.

  17. Variations in large-scale tropical cyclone genesis factors over the western North Pacific in the PMIP3 last millennium simulations

    NASA Astrophysics Data System (ADS)

    Yan, Qing; Wei, Ting; Zhang, Zhongshi

    2017-02-01

    Investigation of past tropical cyclone (TC) activity in the Western North Pacific (WNP) is potentially helpful to enable better understanding of future TC behaviors. In this study, we examine variations in large-scale environmental factors important to TC genesis in the last millennium simulations from the Paleoclimate Modelling Intercomparison Project Phase 3 (PMIP3). The results show that potential intensity, a theoretical prediction of the maximum TC intensity, is increased relative to the last millennium in the north part of the WNP in the Medieval Climate Anomaly (MCA; 950-1200 AD) while it is decreased in the Little Ice Age (LIA; 1600-1850 AD). Vertical wind shear that generally inhibits TC genesis is enhanced (reduced) to the south of 20°N and is reduced (enhanced) to the north in the MCA (LIA). Relative humidity (at 600 hPa) that measures the mid-tropospheric moisture content broadly shows an increase (decrease) in the MCA (LIA). A genesis potential index indicates that conditions are generally favorable (unfavorable) for TC formation in the WNP in the MCA (LIA), especially in the northern part. Taking changes in steering flows into account, there may be an increasing (decreasing) favorability for storm strikes in East Asia in the MCA (LIA). The estimated TC activity is consistent with the geological proxies in Japan, but contradicts with the typhoon records in southern China and Taiwan. This model-data discrepancy is attributed to the limitations in both simulations and reconstructions.

  18. WRF Simulation of the Genesis of Hurricane Javier (2004) in the Eastern Pacific

    NASA Technical Reports Server (NTRS)

    Braun, Scott A.

    2005-01-01

    The Eastern Pacific has the highest frequency of genesis events per unit area of any region worldwide (Elsberry et al 1987). African easterly waves, mesoscale convective systems (MCSs), and topographic effects are thought to play roles in the genesis of tropical cyclones there (Frank and Clark 1980, Velasco and Fritsch 1987, Zehnder 1991, Zehnder and Gall 1991; Farfan and Zehnder 1997). Mozer and Zehnder (1996), using dry, idealized simulations of flow past a large-scale three-dimensional mountain range comparable to the Sierra Madre Mountains of Mexico, showed that upstream flow blocking led to diversion of the flow primarily to the south of the mountains. This flow diversion led to the formation of a low-level, barotropically unstable jet (at a location comparable to the Isthmus of Tehuantepec) and the continuous formation of synoptic-scale vorticity maxima, which they suggested may play a role in tropical cyclogenesis. Farfan and Zehnder (1 997) examined the synoptic-scale circulations that led to the formation of Hurricane Guillermo (1991). Using numerical simulations, they found that flow blocking led to the formation of a low-level easterly jet south of the mountains of Central America and a northeasterly (gap flow) jet over the Gulf of Tehuantepec, which combined with the flow associated with the Intertropical Convergence Zone (ITCZ) to produce a closed cyclonic circulation in the location of Guillermo s formation. As will be discussed in this paper, the evolution of the flow field that was associated with the genesis of Hurricane Javier was similar to that described in Farfan and Zehnder (1997), with well-defined topographic flow features. Here, using a high- resolution simulation with the WRF model, we investigate whether these topographically induced flows played a significant role in the genesis of Javier.

  19. Tropical cyclone genesis potential index over the western North Pacific simulated by CMIP5 models

    NASA Astrophysics Data System (ADS)

    Song, Yajuan; Wang, Lei; Lei, Xiaoyan; Wang, Xidong

    2015-11-01

    Tropical cyclone (TC) genesis over the western North Pacific (WNP) is analyzed using 23 CMIP5 (Coupled Model Intercomparison Project Phase 5) models and reanalysis datasets. The models are evaluated according to TC genesis potential index (GPI). The spatial and temporal variations of the GPI are first calculated using three atmospheric reanalysis datasets (ERA-Interim, NCEP/NCAR Reanalysis-1, and NCEP/DOE Reanalysis-2). Spatial distributions of July-October-mean TC frequency based on the GPI from ERA-interim are more consistent with observed ones derived from IBTrACS global TC data. So, the ERA-interim reanalysis dataset is used to examine the CMIP5 models in terms of reproducing GPI during the period 1982-2005. Although most models possess deficiencies in reproducing the spatial distribution of the GPI, their multimodel ensemble (MME) mean shows a reasonable climatological GPI pattern characterized by a high GPI zone along 20°N in the WNP. There was an upward trend of TC genesis frequency during 1982 to 1998, followed by a downward trend. Both MME results and reanalysis data can represent a robust increasing trend during 1982-1998, but the models cannot simulate the downward trend after 2000. Analysis based on future projection experiments shows that the GPI exhibits no significant change in the first half of the 21st century, and then starts to decrease at the end of the 21st century under the representative concentration pathway (RCP) 2.6 scenario. Under the RCP8.5 scenario, the GPI shows an increasing trend in the vicinity of 20°N, indicating more TCs could possibly be expected over the WNP under future global warming.

  20. Why is the simulated climatology of tropical cyclones so sensitive to the choice of cumulus parameterization scheme in the WRF model?

    NASA Astrophysics Data System (ADS)

    Zhang, Chunxi; Wang, Yuqing

    2018-01-01

    The sensitivity of simulated tropical cyclones (TCs) to the choice of cumulus parameterization (CP) scheme in the advanced Weather Research and Forecasting Model (WRF-ARW) version 3.5 is analyzed based on ten seasonal simulations with 20-km horizontal grid spacing over the western North Pacific. Results show that the simulated frequency and intensity of TCs are very sensitive to the choice of the CP scheme. The sensitivity can be explained well by the difference in the low-level circulation in a height and sorted moisture space. By transporting moist static energy from dry to moist region, the low-level circulation is important to convective self-aggregation which is believed to be related to genesis of TC-like vortices (TCLVs) and TCs in idealized settings. The radiative and evaporative cooling associated with low-level clouds and shallow convection in dry regions is found to play a crucial role in driving the moisture-sorted low-level circulation. With shallow convection turned off in a CP scheme, relatively strong precipitation occurs frequently in dry regions. In this case, the diabatic cooling can still drive the low-level circulation but its strength is reduced and thus TCLV/TC genesis is suppressed. The inclusion of the cumulus momentum transport (CMT) in a CP scheme can considerably suppress genesis of TCLVs/TCs, while changes in the moisture-sorted low-level circulation and horizontal distribution of precipitation are trivial, indicating that the CMT modulates the TCLVs/TCs activities in the model by mechanisms other than the horizontal transport of moist static energy.

  1. The footprints of Saharan Air Layer and lightning on the formation of tropical depressions over the eastern Atlantic Ocean

    NASA Astrophysics Data System (ADS)

    Centeno Delgado, Diana C.

    In this study, the results of an observational analysis and a numerical analysis on the role of the Saharan Air Layer during tropical cyclogenesis (TC-genesis) are described. The observational analysis investigates the interaction of dust particles and lightning during the genesis stage of two developed cases (Hurricanes Helene 2006 and Julia 2010). The Weather Research and Forecasting (WRF) and WRF-Chemistry models were used to include and monitor the aerosols and chemical processes that affect TC-genesis. The numerical modeling involved two developed cases (Hurricanes Helene 2006 and Julia 2010) and two non-developed cases (Non-Developed 2011 and Non-Developed 2012). The Aerosol Optical Depth (AOD) and lightning analysis for Hurricane Helene 2006 demonstrated the time-lag connection through their positive contribution to TC-genesis. The observational analyses supported the fact that both systems developed under either strong or weak dust conditions. From the two cases, the location of strong versus weak dust outbreaks in association with lightning was essential interactions that impacted TC-genesis. Furthermore, including dust particles, chemical processes, and aerosol feedback in the simulations with WRF-CHEM provides results closer to observations than regular WRF. The model advantageously shows the location of the dust particles inside of the tropical system. Overall, the results from this study suggest that the SAL is not a determining factor that affects the formation of tropical cyclones.

  2. A Statistical Model of Tropical Cyclone Tracks in the Western North Pacific with ENSO-Dependent Cyclogenesis

    NASA Technical Reports Server (NTRS)

    Yonekura, Emmi; Hall, Timothy M.

    2011-01-01

    A new statistical model for western North Pacific Ocean tropical cyclone genesis and tracks is developed and applied to estimate regionally resolved tropical cyclone landfall rates along the coasts of the Asian mainland, Japan, and the Philippines. The model is constructed on International Best Track Archive for Climate Stewardship (IBTrACS) 1945-2007 historical data for the western North Pacific. The model is evaluated in several ways, including comparing the stochastic spread in simulated landfall rates with historic landfall rates. Although certain biases have been detected, overall the model performs well on the diagnostic tests, for example, reproducing well the geographic distribution of landfall rates. Western North Pacific cyclogenesis is influenced by El Nino-Southern Oscillation (ENSO). This dependence is incorporated in the model s genesis component to project the ENSO-genesis dependence onto landfall rates. There is a pronounced shift southeastward in cyclogenesis and a small but significant reduction in basinwide annual counts with increasing ENSO index value. On almost all regions of coast, landfall rates are significantly higher in a negative ENSO state (La Nina).

  3. Uncertainties in the Modelled CO2 Threshold for Antarctic Glaciation

    NASA Technical Reports Server (NTRS)

    Gasson, E.; Lunt, D. J.; DeConto, R.; Goldner, A.; Heinemann, M.; Huber, M.; LeGrande, A. N.; Pollard, D.; Sagoo, N.; Siddall, M.; hide

    2014-01-01

    frequently cited atmospheric CO2 threshold for the onset of Antarctic glaciation of approximately780 parts per million by volume is based on the study of DeConto and Pollard (2003) using an ice sheet model and the GENESIS climate model. Proxy records suggest that atmospheric CO2 concentrations passed through this threshold across the Eocene-Oligocene transition approximately 34 million years. However, atmospheric CO2 concentrations may have been close to this threshold earlier than this transition, which is used by some to suggest the possibility of Antarctic ice sheets during the Eocene. Here we investigate the climate model dependency of the threshold for Antarctic glaciation by performing offline ice sheet model simulations using the climate from 7 different climate models with Eocene boundary conditions (HadCM3L, CCSM3, CESM1.0, GENESIS, FAMOUS, ECHAM5 and GISS_ER). These climate simulations are sourced from a number of independent studies, and as such the boundary conditions, which are poorly constrained during the Eocene, are not identical between simulations. The results of this study suggest that the atmospheric CO2 threshold for Antarctic glaciation is highly dependent on the climate model used and the climate model configuration. A large discrepancy between the climate model and ice sheet model grids for some simulations leads to a strong sensitivity to the lapse rate parameter.

  4. Analysis of GALE (Genesis of Atlantic Lows Experiment) Data

    DTIC Science & Technology

    1989-12-01

    being developed to accurately simulate and study the development of extratropical cyclones, which rapidly develop off the east coast of the U.S. and the...the model for the simulation of GALE storms . \\SAIC has worked with the NRL staff in the development of initialization schemes, includir.g a vertical...at the 6th Extratropical Cyclone Workshop of the American Meteorological Society in Monterey, CA, June, 1987, entitled "A Model for the Simulation of

  5. Genesis of Hurricane Sandy (2012) Simulated with a Global Mesoscale Model

    NASA Technical Reports Server (NTRS)

    Shen, Bo-Wen; DeMaria, Mark; Li, J.-L. F.; Cheung, S.

    2013-01-01

    In this study, we investigate the formation predictability of Hurricane Sandy (2012) with a global mesoscale model. We first present five track and intensity forecasts of Sandy initialized at 00Z 22-26 October 2012, realistically producing its movement with a northwestward turn prior to its landfall. We then show that three experiments initialized at 00Z 16-18 October captured the genesis of Sandy with a lead time of up to 6 days and simulated reasonable evolution of Sandy's track and intensity in the next 2 day period of 18Z 21-23 October. Results suggest that the extended lead time of formation prediction is achieved by realistic simulations of multiscale processes, including (1) the interaction between an easterly wave and a low-level westerly wind belt (WWB) and (2) the appearance of the upper-level trough at 200 hPa to Sandy's northwest. The low-level WWB and upper-level trough are likely associated with a Madden-Julian Oscillation.

  6. The impact of Saharan Dust on the genesis and evolution of Hurricane Earl (2010)

    NASA Astrophysics Data System (ADS)

    Pan, B.; Wang, Y.; Hsieh, J. S.; Lin, Y.; Hu, J.; Zhang, R.

    2017-12-01

    Dust, one of the most abundant natural aerosols, can exert substantial radiative and microphysical effects on the regional climate and has potential impacts on the genesis and intensification of tropical cyclones (TCs). A Weather Research and Forecasting Model and the Regional Oceanic Modeling System coupled model (WRF-ROMS) is used to simulate the evolution of Hurricane Earl (2010), of which Earl was interfered by Saharan dust at the TC genesis stage. A new dust module has been implemented to the TAMU two-moment microphysics scheme in the WRF model. It accounts for both dust as Cloud Condensation Nuclei (CCN) and Ice Nuclei (IN). The hurricane track, intensity and precipitation have been compared to the best track data and TRMM precipitation, respectively. The influences of Saharan dust on Hurricane Earl are investigated with dust-CCN, dust-IN, and dust-free scenarios. The analysis shows that Saharan dust changes the latent heat and moisture distribution, invigorates the convections in the hurricane's eyewall, and suppresses the development of Earl. This finding addresses the importance of accounting dust microphysics effect on hurricane predictions.

  7. Simulation of the Genesis of Hurricane Javier (2004) in the Eastern Pacific

    NASA Technical Reports Server (NTRS)

    Braun, Scott

    2005-01-01

    NASA is preparing for the Tropical Cloud Systems and Processes (TCSP) field experiment in July 2005, a joint effort with NOAA to study tropical cloud systems and tropical cyclone genesis in the Eastern Pacific. A major thrust of the TCSP program is the improvement of the understanding and prediction of tropical cyclone genesis, intensity, motion, rainfall potential, and landfall impacts using remote sensing and in-situ data, as well as numerical modeling, particularly as they relate to the three phases of water. The Eastern Pacific has the highest frequency of genesis events per unit area of any region worldwide. African easterly waves, mesoscale convective systems (MCSs), and orographic effects are thought to play roles in the genesis of tropical cyclones there. The general consensus is that tropical depressions form in association with one or more mid-level, mesoscale cyclonic vortices that are generated within the stratiform region of the MCS precursors. To create the warm core tropical depression vortex, however, the midlevel cyclonic circulation must somehow extend down to the surface and the tangential winds must attain sufficient strength (-10 m s- ) to enable the wind-induced surface heat exchange to increase the potential energy of the boundary layer air.

  8. Quantitative modeling of soil genesis processes

    NASA Technical Reports Server (NTRS)

    Levine, E. R.; Knox, R. G.; Kerber, A. G.

    1992-01-01

    For fine spatial scale simulation, a model is being developed to predict changes in properties over short-, meso-, and long-term time scales within horizons of a given soil profile. Processes that control these changes can be grouped into five major process clusters: (1) abiotic chemical reactions; (2) activities of organisms; (3) energy balance and water phase transitions; (4) hydrologic flows; and (5) particle redistribution. Landscape modeling of soil development is possible using digitized soil maps associated with quantitative soil attribute data in a geographic information system (GIS) framework to which simulation models are applied.

  9. Meso-beta scale numerical simulation studies of terrain-induced jet streak mass and momentum perturbations

    NASA Technical Reports Server (NTRS)

    Lin, Yuh-Lang; Kaplan, Michael L.

    1994-01-01

    An in-depth analysis of observed gravity waves and their relationship to precipitation bands over the Montana mesonetwork during the 11-12 July 1981 CCOPE case study indicated two episodes of coherent waves. While geostrophic adjustment, shearing instability, and terrain were all implicated separately or in combination as possible wave generation mechanisms, the lack of upper-air data within the wave genesis region made it difficult to define the genesis processes from observations alone. The first part of this paper, 3D Numerical Modeling Studies of Terrain-Induced Mass/Momentum Perturbations, employs a mesoscale numerical model to help diagnose the intricate early wave generation mechanisms during the first observed gravity wave episode. The meso-beta scale numerical model is used to study various simulations of the role of multiple geostrophic adjustment processes in focusing a region for gravity wave genesis. The second part of this paper, Linear Theory and Theoretical Modeling, investigates the response of non-resting rotating homogeneous and continuously stratified Boussinesq models of the terrestrial atmosphere to temporally impulsive and uniformly propagating three-dimensional localized zonal momentum sources representative of midlatitude jet streaks. The methods of linear perturbation theory applied to the potential vorticity (PV) and wave field equations are used to study the geostrophic adjustment dynamics. The total zonal and meridional wind perturbations are separated into geostrophic and ageostrophic components in order to define and follow the evolution of both the primary and secondary mesocirculations accompanying midlatitude jetogenesis forced by geostrophic adjustment processes. This problem is addressed to help fill the gap in understanding the dynamics and structure of mesoscale inertia-gravity waves forced by geostrophic adjustment processes in simple two-dimensional quiescent current systems and those produced by mesoscale numerical models simulating the orographic and diabatic perturbation of three-dimensional quasi-geostrophically balanced synoptic scale jet streaks associated with complex baroclinic severe storm producing environments.

  10. Tropical Cyclone Genesis: A Dynamician's Point of View

    NASA Astrophysics Data System (ADS)

    Bouali, Safieddine; Leys, Jos

    The paper focuses the route to the maturity of a cyclone as a twist process of the Hadley cell. The approach is qualified by a "dynamician's viewpoint" since the aerologic mechanism of the cyclone genesis is replicated without the classical tools of the meteorological fluid framework. Indeed, we introduce a pure dynamical model of a 2D vertical rotor of an airparcel to emulate the Hadley cell. Twisted by an appropriate feedback to inject geophysical forcing, the simulation displays two stretched solenoid rolls with clockwise and anticlockwise paths representing the Hadley belts wrapping the Earth. When the forcing parameter is higher, computations simulate overlapped whirlwind funnels revealing strong similarities with the structure of cyclones, hurricanes, and typhoons described in the atmospheric science literature. We conjecture that ocean-atmosphere interactions separate and convert a "slice" of the Hadley rotor into a fully tropical cyclone.

  11. Possible influence of dust on hurricane genesis

    NASA Astrophysics Data System (ADS)

    Bretl, Sebastian; Reutter, Philipp; Raible, Christoph C.; Ferrachat, Sylvaine; Lohmann, Ulrike

    2014-05-01

    Tropical Cyclones (TCs) belong to the most extreme events in nature. In the past decade, the possible impact of dust on Atlantic hurricanes receives growing interest. As mineral dust is able to absorb incoming solar radiation and therefore warm the surrounding air, the presence of dust can lead to a reduction of sea surface temperature (SST) and an increase in atmospheric stability. Furthermore, resulting baroclinic effects and the dry Saharan easterly jet lead to an enhanced vertical shear of the horizontal winds. SST, stability, moisture and vertical wind shear are known to potentially impact hurricane activity. But how Saharan dust influences these prerequisites for hurricane formation is not yet clear. Some dynamical mechanisms induced by the SAL might even strengthen hurricanes. An adequate framework for investigating the possible impact of dust on hurricanes is comparing high resolution simulations (~0.5°x0.5°, 31 vertical levels) with and without radiatively active dust aerosols. To accomplish this task, we are using the general circulation model ECHAM6 coupled to a modified version of the aerosol model HAM, ECHAM6-HAM-Dust. Instead of the five aerosol species HAM normally contains, the modified version takes only insoluble dust into account, but modifies the scavenging parameters in order to have a similar lifetime of dust as in the full ECHAM6-HAM. All remaining aerosols are prescribed. To evaluate the effects of dust on hurricanes, a TC detection and tracking method is applied on the results. ECHAM6-HAM-Dust was used in two configurations, one with radiatively active dust aerosols and one with dust being not radiatively active. For both set-ups, 10 Monte-Carlo simulations of the year 2005 were performed. A statistical method which identifies controlling parameters of hurricane genesis was applied on North Atlantic developing and non-developing disturbances in all simulations, comparing storms in the two sets of simulations. Hereby, dust can be assigned a more influencing role on TC genesis in the simulations with active dust. Despite dust is seeming to have a negative influence on TC genesis, the relative importance of dust compared to the sea surface temperature (SST) cannot be determined thoroughly. This is largely due to a similar pattern of SST and dust off the west coast of Africa, so that possible effects of dust and SST could hardly be separated.

  12. Analysis and High-Resolution Modeling of Tropical Cyclogenesis During the TCS-08 and TPARC Field Campaign

    DTIC Science & Technology

    2014-10-13

    synoptic and dynamic aspects of cyclogenesis, a multi-nested WRF model (with 2 km resolution in the innermost mesh) will be used to simulate both...intraseasonal and interannual variability of TC activity in the WNP. For the data assimilation task, WRF 3DVar assimilation system will be employed...simulated using WRF . This genesis is associated with Rossby wave energy dispersion of a pre- existing TC Bills (2000). Using the reanalysis data as an

  13. Evaluation of WRF model simulations of tropical cyclones in the western North Pacific over the CORDEX East Asia domain

    NASA Astrophysics Data System (ADS)

    Shen, Wenqiang; Tang, Jianping; Wang, Yuan; Wang, Shuyu; Niu, Xiaorui

    2017-04-01

    In this study, the characteristics of tropical cyclones (TCs) over the East Asia Coordinated Regional Downscaling Experiment domain are examined with the Weather Research and Forecasting (WRF) model. Eight 20-year (1989-2008) simulations are performed using the WRF model, with lateral boundary forcing from the ERA-Interim reanalysis, to test the sensitivity of TC simulation to interior spectral nudging (SN, including nudging time interval, nudging variables) and radiation schemes [Community Atmosphere Model (CAM), Rapid Radiative Transfer Model (RRTM)]. The simulated TCs are compared with the observation from the Regional Specialized Meteorological Centers TC best tracks. It is found that all WRF runs can simulate the climatology of key TC features such as the tracks and location/frequency of genesis reasonably well, and reproduce the inter-annual variations and seasonal cycle of TC counts. The SN runs produce enhanced TC activity compare to the runs without SN. The thermodynamic profile suggests that nudging with horizontal wind increases the unstable of thermodynamic states in tropics, which results in excessive TCs genesis. The experiments with wind and temperature nudging improve the overestimation of TCs numbers, especially suppress the TCs intensification by correct the thermodynamic profile. Weak SN coefficient enhances TCs activity significantly even with wind and temperature nudging. The analysis of TCs numbers and large scale circulation shows that the SN parameters adopted in our experiments do not appear to suppress the formation of TC. The excessive TCs activity in CAM runs relative to RRTM runs are also due to the enhanced atmospheric instability.

  14. Generalized Galileons: instabilities of bouncing and Genesis cosmologies and modified Genesis

    NASA Astrophysics Data System (ADS)

    Libanov, M.; Mironov, S.; Rubakov, V.

    2016-08-01

    We study spatially flat bouncing cosmologies and models with the early-time Genesis epoch in a popular class of generalized Galileon theories. We ask whether there exist solutions of these types which are free of gradient and ghost instabilities. We find that irrespectively of the forms of the Lagrangian functions, the bouncing models either are plagued with these instabilities or have singularities. The same result holds for the original Genesis model and its variants in which the scale factor tends to a constant as t → -∞. The result remains valid in theories with additional matter that obeys the Null Energy Condition and interacts with the Galileon only gravitationally. We propose a modified Genesis model which evades our no-go argument and give an explicit example of healthy cosmology that connects the modified Genesis epoch with kination (the epoch still driven by the Galileon field, which is a conventional massless scalar field at that stage).

  15. Higher-order harmonics coupling in different free-electron laser codes

    NASA Astrophysics Data System (ADS)

    Giannessi, L.; Freund, H. P.; Musumeci, P.; Reiche, S.

    2008-08-01

    The capability for simulation of the dynamics of a free-electron laser including the higher-order harmonics in linear undulators exists in several existing codes as MEDUSA [H.P. Freund, S.G. Biedron, and S.V. Milton, IEEE J. Quantum Electron. 27 (2000) 243; H.P. Freund, Phys. Rev. ST-AB 8 (2005) 110701] and PERSEO [L. Giannessi, Overview of Perseo, a system for simulating FEL dynamics in Mathcad, < http://www.jacow.org>, in: Proceedings of FEL 2006 Conference, BESSY, Berlin, Germany, 2006, p. 91], and has been recently implemented in GENESIS 1.3 [See < http://www.perseo.enea.it>]. MEDUSA and GENESIS also include the dynamics of even harmonics induced by the coupling through the betatron motion. In addition MEDUSA, which is based on a non-wiggler averaged model, is capable of simulating the generation of even harmonics in the transversally cold beam regime, i.e. when the even harmonic coupling arises from non-linear effects associated with longitudinal particle dynamics and not to a finite beam emittance. In this paper a comparison between the predictions of the codes in different conditions is given.

  16. Determining relevant parameters for a statistical tropical cyclone genesis tool based upon global model output

    NASA Astrophysics Data System (ADS)

    Halperin, D.; Hart, R. E.; Fuelberg, H. E.; Cossuth, J.

    2013-12-01

    Predicting tropical cyclone (TC) genesis has been a vexing problem for forecasters. While the literature describes environmental conditions which are necessary for TC genesis, predicting if and when a specific disturbance will organize and become a TC remains a challenge. As recently as 5-10 years ago, global models possessed little if any skill in forecasting TC genesis. However, due to increased resolution and more advanced model parameterizations, we have reached the point where global models can provide useful TC genesis guidance to operational forecasters. A recent study evaluated five global models' ability to predict TC genesis out to four days over the North Atlantic basin (Halperin et al. 2013). The results indicate that the models are indeed able to capture the genesis time and location correctly a fair percentage of the time. The study also uncovered model biases. For example, probability of detection and false alarm rate varies spatially within the basin. Also, as expected, the models' performance decreases with increasing lead time. In order to explain these and other biases, it is useful to analyze the model-indicated genesis events further to determine whether or not there are systematic differences between successful forecasts (hits), false alarms, and miss events. This study will examine composites of a number of physically-relevant environmental parameters (e.g., magnitude of vertical wind shear, aerially averaged mid-level relative humidity) and disturbance-based parameters (e.g., 925 hPa maximum wind speed, vertical alignment of relative vorticity) among each TC genesis event classification (i.e., hit, false alarm, miss). We will use standard statistical tests (e.g., Student's t test, Mann-Whitney-U Test) to calculate whether or not any differences are statistically significant. We also plan to discuss how these composite results apply to a few illustrative case studies. The results may help determine which aspects of the forecast are (in)correct and whether the incorrect aspects can be bias-corrected. This, in turn, may allow us to further enhance probabilistic forecasts of TC genesis.

  17. The APS SASE FEL : modeling and code comparison.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Biedron, S. G.

    A self-amplified spontaneous emission (SASE) free-electron laser (FEL) is under construction at the Advanced Photon Source (APS). Five FEL simulation codes were used in the design phase: GENESIS, GINGER, MEDUSA, RON, and TDA3D. Initial comparisons between each of these independent formulations show good agreement for the parameters of the APS SASE FEL.

  18. Simulations of ultra-high energy cosmic rays in the local Universe and the origin of cosmic magnetic fields

    NASA Astrophysics Data System (ADS)

    Hackstein, S.; Vazza, F.; Brüggen, M.; Sorce, J. G.; Gottlöber, S.

    2018-04-01

    We simulate the propagation of cosmic rays at ultra-high energies, ≳1018 eV, in models of extragalactic magnetic fields in constrained simulations of the local Universe. We use constrained initial conditions with the cosmological magnetohydrodynamics code ENZO. The resulting models of the distribution of magnetic fields in the local Universe are used in the CRPROPA code to simulate the propagation of ultra-high energy cosmic rays. We investigate the impact of six different magneto-genesis scenarios, both primordial and astrophysical, on the propagation of cosmic rays over cosmological distances. Moreover, we study the influence of different source distributions around the Milky Way. Our study shows that different scenarios of magneto-genesis do not have a large impact on the anisotropy measurements of ultra-high energy cosmic rays. However, at high energies above the Greisen-Zatsepin-Kuzmin (GZK)-limit, there is anisotropy caused by the distribution of nearby sources, independent of the magnetic field model. This provides a chance to identify cosmic ray sources with future full-sky measurements and high number statistics at the highest energies. Finally, we compare our results to the dipole signal measured by the Pierre Auger Observatory. All our source models and magnetic field models could reproduce the observed dipole amplitude with a pure iron injection composition. Our results indicate that the dipole is observed due to clustering of secondary nuclei in direction of nearby sources of heavy nuclei. A light injection composition is disfavoured, since the increase in dipole angular power from 4 to 8 EeV is too slow compared to observation by the Pierre Auger Observatory.

  19. Generalized Galileons: instabilities of bouncing and Genesis cosmologies and modified Genesis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Libanov, M.; Moscow Institute of Physics and Technology,Institutskii per. 9, 141700 Dolgoprudny, Moscow Region; Mironov, S.

    2016-08-18

    We study spatially flat bouncing cosmologies and models with the early-time Genesis epoch in a popular class of generalized Galileon theories. We ask whether there exist solutions of these types which are free of gradient and ghost instabilities. We find that irrespectively of the forms of the Lagrangian functions, the bouncing models either are plagued with these instabilities or have singularities. The same result holds for the original Genesis model and its variants in which the scale factor tends to a constant as t→−∞. The result remains valid in theories with additional matter that obeys the Null Energy Condition andmore » interacts with the Galileon only gravitationally. We propose a modified Genesis model which evades our no-go argument and give an explicit example of healthy cosmology that connects the modified Genesis epoch with kination (the epoch still driven by the Galileon field, which is a conventional massless scalar field at that stage).« less

  20. Adventures in Parallel Processing: Entry, Descent and Landing Simulation for the Genesis and Stardust Missions

    NASA Technical Reports Server (NTRS)

    Lyons, Daniel T.; Desai, Prasun N.

    2005-01-01

    This paper will describe the Entry, Descent and Landing simulation tradeoffs and techniques that were used to provide the Monte Carlo data required to approve entry during a critical period just before entry of the Genesis Sample Return Capsule. The same techniques will be used again when Stardust returns on January 15, 2006. Only one hour was available for the simulation which propagated 2000 dispersed entry states to the ground. Creative simulation tradeoffs combined with parallel processing were needed to provide the landing footprint statistics that were an essential part of the Go/NoGo decision that authorized release of the Sample Return Capsule a few hours before entry.

  1. Modeling of Shoreline Changes of Tulamben Coast, Bali Indonesia

    NASA Astrophysics Data System (ADS)

    Yuanita, Nita; Pratama, Roka; Husrin, Semeidi

    2015-04-01

    Modeling of Shoreline Changes of Tulamben Coast, Bali Indonesia Tulamben coast is located in Lombok Strait on the northeastern coast of Bali island, Indonesia, as part of Karang Asem district. Severe erosion along the coastline has long been occurred in Karang Asem area and threatening houses, religious buildings (Hindu temples), and a national heritage site. As one of most popular diving site in Bali Island, Tulamben attracted many local and international tourist since 1980. The main attraction of Tulamben diving site is the USAT Liberty ship that was shipwrecked in Tulamben beach in 1942, after attacked by Japanese torpedo in Lombok Strait. Currently about 150 diver visit Tulamben per day. Due to physical changes of coastal environmental such as coastal erosion, sliding, and scouring, the shipwreck is vulnerable. It had been slipped off the beach several times and is predicted would be moved to deeper offshore floor if it is not protected. Coastal erosion in Karang Asem district is occurred probably due to interaction between cross-shore and long-shore wave-generated current and river sand supply decreasing after sand mining activities. In this study, the effect of cross-shore and longshore transport to coastal erosion in Tulamben is analyzed by doing numerical model. Numerical simulation of shoreline changes is performed by using Beach Processes Module of CEDAS (Coastal Engineering Design and Analysis System) consists of SBEACH and GENESIS. The model domain is covered Karang Asem coastline about 60 km length and wave data is calculated from hourly wind data (10 years). Simulated shoreline is calibrated using shoreline data from 1972 to 2013. Using calibrated model, then the simulation is performed from 2003 - 2013. From the simulation it is determined that longshore current and longshore sediment contribute to coastal erosion in Tulamben. Based on model results, several alternatives of general layout and configuration of coastal protection structures is proposed. The most optimum coastal protection system is determined by simulating proposed alternative using GENESIS.

  2. MaRIE Undulator & XFEL Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nguyen, Dinh Cong; Marksteiner, Quinn R.; Anisimov, Petr Mikhaylovich

    The 22 slides in this presentation treat the subject under the following headings: MaRIE XFEL Performance Parameters, Input Electron Beam Parameters, Undulator Design, Genesis Simulations, Risks, and Summary It is concluded that time-dependent Genesis simulations show the MaRIE XFEL can deliver the number of photons within the required bandwidth, provided a number of assumptions are met; the highest risks are associated with the electron beam driving the XFEL undulator; and risks associated with the undulator and/or distributed seeding technique may be evaluated or retired by performing early validation experiments.

  3. Genesis of Typhoon Nari (2001) from a mesoscale convective system

    NASA Astrophysics Data System (ADS)

    Zhang, Da-Lin; Tian, Liqing; Yang, Ming-Jen

    2011-12-01

    In this study, the origin and genesis of Typhoon Nari (2001) as well as its erratic looping track, are examined using large-scale analysis, satellite observations, and a 4 day nested, cloud-resolving simulation with the finest grid size of 1.33 km. Observational analysis reveals that Nari could be traced 5 days back to a diurnally varying mesoscale convective system with growing cyclonic vorticity and relative humidity in the lower troposphere and that it evolved from a mesoscale convective vortex (MCV) as moving over a warm ocean under the influence of a subtropical high, a weak westerly baroclinic disturbance, an approaching-and-departing Typhoon Danas to the east, and the Kuroshio Current. Results show that the model reproduces the genesis, final intensity, looping track, and the general convective activity of Nari during the 4 day period. It also captures two deep subvortices at the eye-eyewall interface that are similar to those previously observed, a few spiral rainbands, and a midget storm size associated with Nari's relatively dry and stable environment. We find that (1) continuous convective overturning within the MCV stretches the low-level vorticity and moistens a deep mesoscale column that are both favorable for genesis; (2) Nari's genesis does not occur until after the passage of the baroclinic disturbance; (3) convective asymmetry induces a smaller-sized vortex circulation from the preexisting MCV; (4) the vortex-vortex interaction with Danas leads to Nari's looping track and temporal weakening; and (5) midlevel convergence associated with the subtropical high and Danas accounts for the generation of a nearly upright eyewall.

  4. On gravitational chirality as the genesis of astrophysical jets

    NASA Astrophysics Data System (ADS)

    Tucker, R. W.; Walton, T. J.

    2017-02-01

    It has been suggested that single and double jets observed emanating from certain astrophysical objects may have a purely gravitational origin. We discuss new classes of plane-fronted and pulsed gravitational wave solutions to the equation for perturbations of Ricci-flat spacetimes around Minkowski metrics, as models for the genesis of such phenomena. These solutions are classified in terms of their chirality and generate a family of non-stationary spacetime metrics. Particular members of these families are used as backgrounds in analysing time-like solutions to the geodesic equation for test particles. They are found numerically to exhibit both single and double jet-like features with dimensionless aspect ratios suggesting that it may be profitable to include such backgrounds in simulations of astrophysical jet dynamics from rotating accretion discs involving electromagnetic fields.

  5. Comparison of thunderstorm simulations from WRF-NMM and WRF-ARW models over East Indian Region.

    PubMed

    Litta, A J; Mary Ididcula, Sumam; Mohanty, U C; Kiran Prasad, S

    2012-01-01

    The thunderstorms are typical mesoscale systems dominated by intense convection. Mesoscale models are essential for the accurate prediction of such high-impact weather events. In the present study, an attempt has been made to compare the simulated results of three thunderstorm events using NMM and ARW model core of WRF system and validated the model results with observations. Both models performed well in capturing stability indices which are indicators of severe convective activity. Comparison of model-simulated radar reflectivity imageries with observations revealed that NMM model has simulated well the propagation of the squall line, while the squall line movement was slow in ARW. From the model-simulated spatial plots of cloud top temperature, we can see that NMM model has better captured the genesis, intensification, and propagation of thunder squall than ARW model. The statistical analysis of rainfall indicates the better performance of NMM than ARW. Comparison of model-simulated thunderstorm affected parameters with that of the observed showed that NMM has performed better than ARW in capturing the sharp rise in humidity and drop in temperature. This suggests that NMM model has the potential to provide unique and valuable information for severe thunderstorm forecasters over east Indian region.

  6. Short-term Climate Simulations of African Easterly Waves with a Global Mesoscale Model

    NASA Astrophysics Data System (ADS)

    Shen, B. W.

    2015-12-01

    Recent high-resolution global model simulations ( Shen et al., 2010a, 2010b, 2012; 2013), which were conducted to examine the role of multiscale processes associated with tropical waves in the predictability of mesoscale tropical cyclones (TCs), suggested that a large-scale system (e.g., tropical waves) can provide determinism on the prediction of TC genesis, making it possible to extend the lead time of genesis predictions. Selected cases include the relationship between (i) TC Nargis (2008) and an Equatorial Rossby wave; (ii) Hurricane Helene (2006) and an intensifying African Easterly Wave (AEW); (iii) Twin TCs (2002) and a mixed Rossby-gravity wave during an active phase of the Madden Julian Oscillation (MJO); (iv) Hurricane Sandy (2012) and tropical waves during an active phase of the MJO. In this talk, thirty-day simulations with different model configurations are presented to examine the model's ability to simulate AEWs and MJOs and their association with tropical cyclogenesis. I will first discuss the simulations of the initiation and propagation of 6 consecutive AEWs in late August 2006 and the mean state of the African easterly jet (AEJ) over both Africa and downstream in the tropical Atlantic. By comparing our simulations with NCEP analysis and satellite data (e.g., TRMM), it is shown that the statistical characteristics of individual AEWs are realistically simulated with larger errors in the 5th and th AEWs. Results from the sensitivity experiments suggest the following: 1) accurate representations of non-linear interactions between the atmosphere and land processes are crucial for improving the simulations of the AEWs and the AEJ; 2) improved simulations of an individual AEW and its interaction with local environments (e.g., the Guinea Highlands) could provide determinism for hurricane formation downstream. Of interest is the potential to extend the lead time for predicting hurricane formation (e.g., a lead time of up to 22 days) as the 4th AEW is realistically simulated; 3) however, the dependence of AEW simulations on accurate dynamic and surface initial conditions and boundary conditions poses a challenge in simulating their modulation on hurricane activity. In addition to the simulations of AEWs, I will also present the 30-day simulations of selected MJO cases.

  7. Quasi-Equilibria of the Rotunno-Emanuel Tropical Cyclone Model

    NASA Technical Reports Server (NTRS)

    Chao, Winston C.; Chen, Baode

    2003-01-01

    Long-term integrations using the Rotunno-Emanuel (RE) model demonstrate that given sufficient elapsed time the weak initial vortex specified by R E can also lead to tropical cyclogenesis, albeit at a slower growth rate. Thus the RE notion of the finite-amplitude nature of tropical cyclogenesis is valid only if the period of examination is limited to the first eight days. These results also show that, if initial vortex as specified by RE is used, prior to cyclogenesis the model state does not resemble the observed pre-genesis disturbances in the sense that there is no precipitation in the center of the disturbance. Another experiment using the same model but with the initial vortex replaced by a disturbance with a different structure shows that a state resembling the observed pre-genesis disturbances can be simulated and this state can lead to spontaneous cyclogenesis, a rapid transition between two quasi-equilibria. This spontaneous cyclogenesis is associated with the generation of a new convective region at large radius and its subsequent contraction, which reminds one of the observed eye-wall replacement, but the distinction from the latter is obvious.

  8. The Modulation of Tropical Storm Activity in the Western North Pacific by the Madden-Julian Oscillation in GEOS-5 AGCM Experiments

    NASA Technical Reports Server (NTRS)

    Kim, Dongmin; Lee, Myong-In; Kim, Hye-Mi; Schubert, Siegfried D.; Yoo, Jin Ho

    2014-01-01

    This study examines the influence of the Madden-Julian Oscillation (MJO) on tropical storm (TS) activity in the western North Pacific, using observations and GEOS-5 simulations at 50-km horizontal resolution. While GEOS-5 produces an MJO of faster propagation and weaker amplitude, it nevertheless reproduces the observed modulation of TS activity by the MJO with the highest TS genesis and increased track density in the active phases of MJO. The study suggests that the simulation of the sub-seasonal variability of TS activity could be improved by improving the simulations of the MJO in climate models.

  9. Pulsatile blood flow in elastic artery with model aneurysm

    NASA Astrophysics Data System (ADS)

    Nikolov, N.; Radev, St.; Tabakova, S.

    2017-11-01

    The mathematical modeling and numerical simulations are expected to play an important role to predict the genesis of different cardiovascular diseases, such as the formation and rupture of aneurysms. In the present work, the numerical solutions of the oscillatory blood flow are constructed for an elastic artery with a model aneurysm by use of the software ANSYS. It is observed that the artery elastic strain behaves in a different way: stably or unstably depending on the different combinations between the flow parameter (outlet pressure) and the elastic modulus of the artery wall.

  10. Meso-beta scale numerical simulation studies of terrain-induced jet streak mass/momentum perturbations

    NASA Technical Reports Server (NTRS)

    Lin, Yuh-Lang; Kaplan, Michael L.

    1994-01-01

    An in-depth analysis of observed gravity waves and their relationship to precipitation bands over the Montana mesonetwork during the 1981 CCOPE case study indicates that there were two episodes of coherent internal gravity waves. One of the fundamental unanswered questions from this research, however, concerns the dynamical processes which generated the observed waves, all of which originated from the region encompassing the borders of Montana, Idaho, and Wyoming. While geostrophic adjustment, shearing instability, and terrain where all implicated separately or in concert as possible wave generation mechanisms, the lack of upper-air data within the wave genesis region made it difficult to rigorously define the genesis processes from observations alone. In this report we employ a mesoscale numerical model to help diagnose the intricate early wave generation mechanisms during the first observed wave episode.

  11. Genesis of the Lunar Landing Vehicle

    NASA Technical Reports Server (NTRS)

    Gelzer, Christian

    2009-01-01

    The author examines early research regarding return flight from a Moon landing made prior to President Kennedy's 1961 challenge to put men on the Moon before the end of the decade. Organizations involved in early research include NACA, the Flight Research Center (now Dryden) Bell Aircraft Corporation. The discussion focuses on development of a flight simulator to model the Moon's reduced gravity and development of the Lunar Landing Research Vehicle.

  12. Simulation Platform: a cloud-based online simulation environment.

    PubMed

    Yamazaki, Tadashi; Ikeno, Hidetoshi; Okumura, Yoshihiro; Satoh, Shunji; Kamiyama, Yoshimi; Hirata, Yutaka; Inagaki, Keiichiro; Ishihara, Akito; Kannon, Takayuki; Usui, Shiro

    2011-09-01

    For multi-scale and multi-modal neural modeling, it is needed to handle multiple neural models described at different levels seamlessly. Database technology will become more important for these studies, specifically for downloading and handling the neural models seamlessly and effortlessly. To date, conventional neuroinformatics databases have solely been designed to archive model files, but the databases should provide a chance for users to validate the models before downloading them. In this paper, we report our on-going project to develop a cloud-based web service for online simulation called "Simulation Platform". Simulation Platform is a cloud of virtual machines running GNU/Linux. On a virtual machine, various software including developer tools such as compilers and libraries, popular neural simulators such as GENESIS, NEURON and NEST, and scientific software such as Gnuplot, R and Octave, are pre-installed. When a user posts a request, a virtual machine is assigned to the user, and the simulation starts on that machine. The user remotely accesses to the machine through a web browser and carries out the simulation, without the need to install any software but a web browser on the user's own computer. Therefore, Simulation Platform is expected to eliminate impediments to handle multiple neural models that require multiple software. Copyright © 2011 Elsevier Ltd. All rights reserved.

  13. Reprint of: Simulation Platform: a cloud-based online simulation environment.

    PubMed

    Yamazaki, Tadashi; Ikeno, Hidetoshi; Okumura, Yoshihiro; Satoh, Shunji; Kamiyama, Yoshimi; Hirata, Yutaka; Inagaki, Keiichiro; Ishihara, Akito; Kannon, Takayuki; Usui, Shiro

    2011-11-01

    For multi-scale and multi-modal neural modeling, it is needed to handle multiple neural models described at different levels seamlessly. Database technology will become more important for these studies, specifically for downloading and handling the neural models seamlessly and effortlessly. To date, conventional neuroinformatics databases have solely been designed to archive model files, but the databases should provide a chance for users to validate the models before downloading them. In this paper, we report our on-going project to develop a cloud-based web service for online simulation called "Simulation Platform". Simulation Platform is a cloud of virtual machines running GNU/Linux. On a virtual machine, various software including developer tools such as compilers and libraries, popular neural simulators such as GENESIS, NEURON and NEST, and scientific software such as Gnuplot, R and Octave, are pre-installed. When a user posts a request, a virtual machine is assigned to the user, and the simulation starts on that machine. The user remotely accesses to the machine through a web browser and carries out the simulation, without the need to install any software but a web browser on the user's own computer. Therefore, Simulation Platform is expected to eliminate impediments to handle multiple neural models that require multiple software. Copyright © 2011 Elsevier Ltd. All rights reserved.

  14. Comparison of Thunderstorm Simulations from WRF-NMM and WRF-ARW Models over East Indian Region

    PubMed Central

    Litta, A. J.; Mary Ididcula, Sumam; Mohanty, U. C.; Kiran Prasad, S.

    2012-01-01

    The thunderstorms are typical mesoscale systems dominated by intense convection. Mesoscale models are essential for the accurate prediction of such high-impact weather events. In the present study, an attempt has been made to compare the simulated results of three thunderstorm events using NMM and ARW model core of WRF system and validated the model results with observations. Both models performed well in capturing stability indices which are indicators of severe convective activity. Comparison of model-simulated radar reflectivity imageries with observations revealed that NMM model has simulated well the propagation of the squall line, while the squall line movement was slow in ARW. From the model-simulated spatial plots of cloud top temperature, we can see that NMM model has better captured the genesis, intensification, and propagation of thunder squall than ARW model. The statistical analysis of rainfall indicates the better performance of NMM than ARW. Comparison of model-simulated thunderstorm affected parameters with that of the observed showed that NMM has performed better than ARW in capturing the sharp rise in humidity and drop in temperature. This suggests that NMM model has the potential to provide unique and valuable information for severe thunderstorm forecasters over east Indian region. PMID:22645480

  15. Mechanistic, Mathematical Model to Predict the Dynamics of Tissue Genesis in Bone Defects via Mechanical Feedback and Mediation of Biochemical Factors

    PubMed Central

    Moore, Shannon R.; Saidel, Gerald M.; Knothe, Ulf; Knothe Tate, Melissa L.

    2014-01-01

    The link between mechanics and biology in the generation and the adaptation of bone has been well studied in context of skeletal development and fracture healing. Yet, the prediction of tissue genesis within - and the spatiotemporal healing of - postnatal defects, necessitates a quantitative evaluation of mechano-biological interactions using experimental and clinical parameters. To address this current gap in knowledge, this study aims to develop a mechanistic mathematical model of tissue genesis using bone morphogenetic protein (BMP) to represent of a class of factors that may coordinate bone healing. Specifically, we developed a mechanistic, mathematical model to predict the dynamics of tissue genesis by periosteal progenitor cells within a long bone defect surrounded by periosteum and stabilized via an intramedullary nail. The emergent material properties and mechanical environment associated with nascent tissue genesis influence the strain stimulus sensed by progenitor cells within the periosteum. Using a mechanical finite element model, periosteal surface strains are predicted as a function of emergent, nascent tissue properties. Strains are then input to a mechanistic mathematical model, where mechanical regulation of BMP-2 production mediates rates of cellular proliferation, differentiation and tissue production, to predict healing outcomes. A parametric approach enables the spatial and temporal prediction of endochondral tissue regeneration, assessed as areas of cartilage and mineralized bone, as functions of radial distance from the periosteum and time. Comparing model results to histological outcomes from two previous studies of periosteum-mediated bone regeneration in a common ovine model, it was shown that mechanistic models incorporating mechanical feedback successfully predict patterns (spatial) and trends (temporal) of bone tissue regeneration. The novel model framework presented here integrates a mechanistic feedback system based on the mechanosensitivity of periosteal progenitor cells, which allows for modeling and prediction of tissue regeneration on multiple length and time scales. Through combination of computational, physical and engineering science approaches, the model platform provides a means to test new hypotheses in silico and to elucidate conditions conducive to endogenous tissue genesis. Next generation models will serve to unravel intrinsic differences in bone genesis by endochondral and intramembranous mechanisms. PMID:24967742

  16. Tropical cyclone prediction skills - MJO and ENSO dependence in S2S data sets

    NASA Astrophysics Data System (ADS)

    Lee, C. Y.; Camargo, S.; Vitart, F.; Sobel, A. H.; Tippett, M.

    2017-12-01

    The El Niño-Southern Oscillation (ENSO) and the Madden-Julian Oscillation (MJO) are two important climate controls on tropical cyclone (TC) activity. The seasonal prediction skill of dynamical models is determined in large part by their accurate representations of the ENSO-TC relationship. Regarding intraseasonal TC variability, observations suggest MJO to be the primary control. Given the ongoing effort to develop dynamical seasonal-to-subseasonal (S2S) TC predictions, it is important to examine whether the global models, running on S2S timescales, are able to reproduce these known ENSO-TC and MJO-TC relationships, and how this ability affects forecasting skill. Results from the S2S project (from F. Vitart) suggest that global models have skill in predicting MJO phase with up to two weeks of lead time (four weeks for ECMWF). Meanwhile, our results show that, qualitatively speaking, the MJO-TC relationship in storm genesis is reasonably captured, with some models (e.g., ECMWF, BoM, NCEP, MetFr) performing better than the others. However, we also find that model skill in predicting basin-wide genesis and accumulated cyclone energy (ACE) are mainly due to the models' ability to capture the climatological seasonality. Removing the seasonality significantly reduces the models' skill; even the best model (ECMWF) in the most reliable basin (western north Pacific and Atlantic) has very little skill (close to 0.1 in Brier skill score for genesis and close to 0 in rank probability skill score for ACE). This brings up the question: do any factors contribute to intraseasonal TC prediction skill other than seasonality? Is the low skill, after removing the seasonality, due to poor MJO and ENSO simulations, or to poor representation of other ENSO-TC or MJO-TC relationships, such as ENSO's impact on the storm tracks? We will quantitatively discuss the dependence of the TC prediction skill on ENSO and MJO, focusing on Western North Pacific and Atlantic, where we have sufficient sample sizes, and the S2S TC predictions are relatively more skillful. Various skill scores will be applied to genesis and ACE, with subsets of data binned based on ENSO and MJO status. We will also look at MJO and ENSO's impact on TC tracks through cluster analysis, and analyze model skill in each cluster.

  17. Cosmological bounce and Genesis beyond Horndeski

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kolevatov, R.; Mironov, S.; Volkova, V.

    2017-08-01

    We study 'classical' bouncing and Genesis models in beyond Horndeski theory. We give an example of spatially flat bouncing solution that is non-singular and stable throughout the whole evolution. We also provide an example of stable geodesically complete Genesis with similar features. The model is arranged in such a way that the scalar field driving the cosmological evolution initially behaves like full-fledged beyond Horndeski, whereas at late times it becomes a massless scalar field minimally coupled to gravity.

  18. Modeling of unit operating considerations in generating-capacity reliability evaluation. Volume 1. Mathematical models, computing methods, and results. Final report. [GENESIS, OPCON and OPPLAN

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Patton, A.D.; Ayoub, A.K.; Singh, C.

    1982-07-01

    Existing methods for generating capacity reliability evaluation do not explicitly recognize a number of operating considerations which may have important effects in system reliability performance. Thus, current methods may yield estimates of system reliability which differ appreciably from actual observed reliability. Further, current methods offer no means of accurately studying or evaluating alternatives which may differ in one or more operating considerations. Operating considerations which are considered to be important in generating capacity reliability evaluation include: unit duty cycles as influenced by load cycle shape, reliability performance of other units, unit commitment policy, and operating reserve policy; unit start-up failuresmore » distinct from unit running failures; unit start-up times; and unit outage postponability and the management of postponable outages. A detailed Monte Carlo simulation computer model called GENESIS and two analytical models called OPCON and OPPLAN have been developed which are capable of incorporating the effects of many operating considerations including those noted above. These computer models have been used to study a variety of actual and synthetic systems and are available from EPRI. The new models are shown to produce system reliability indices which differ appreciably from index values computed using traditional models which do not recognize operating considerations.« less

  19. North Atlantic Tropical Cyclones: historical simulations and future changes with the new high-resolution Arpege AGCM.

    NASA Astrophysics Data System (ADS)

    Pilon, R.; Chauvin, F.; Palany, P.; Belmadani, A.

    2017-12-01

    A new version of the variable high-resolution Meteo-France Arpege atmospheric general circulation model (AGCM) has been developed for tropical cyclones (TC) studies, with a focus on the North Atlantic basin, where the model horizontal resolution is 15 km. Ensemble historical AMIP (Atmospheric Model Intercomparison Project)-type simulations (1965-2014) and future projections (2020-2080) under the IPCC (Intergovernmental Panel on Climate Change) representative concentration pathway (RCP) 8.5 scenario have been produced. TC-like vortices tracking algorithm is used to investigate TC activity and variability. TC frequency, genesis, geographical distribution and intensity are examined. Historical simulations are compared to best-track and reanalysis datasets. Model TC frequency is generally realistic but tends to be too high during the rst decade of the historical simulations. Biases appear to originate from both the tracking algorithm and model climatology. Nevertheless, the model is able to simulate extremely well intense TCs corresponding to category 5 hurricanes in the North Atlantic, where grid resolution is highest. Interaction between developing TCs and vertical wind shear is shown to be contributing factor for TC variability. Future changes in TC activity and properties are also discussed.

  20. Differences in the stress distribution in the distal femur between patellofemoral joint replacement and total knee replacement: a finite element study

    PubMed Central

    2012-01-01

    Background Patellofemoral joint replacement is a successful treatment option for isolated patellofemoral osteoarthritis. However, results of later conversion to total knee replacement may be compromised by periprosthetic bone loss. Previous clinical studies have demonstrated a decrease in distal femoral bone mineral density after patellofemoral joint replacement. It is unclear whether this is due to periprosthetic stress shielding. The main objective of the current study was to evaluate the stress shielding effect of prosthetic replacement with 2 different patellofemoral prosthetic designs and with a total knee prosthesis. Methods We developed a finite element model of an intact patellofemoral joint, and finite element models of patellofemoral joint replacement with a Journey PFJ prosthesis, a Richards II prosthesis, and a Genesis II total knee prosthesis. For each of these 4 finite element models, the average Von Mises stress in 2 clinically relevant regions of interest were evaluated during a simulated squatting movement until 120 degrees of flexion. Results During deep knee flexion, in the anterior region of interest, the average Von Mises stress with the Journey PFJ design was comparable to the physiological knee, while reduced by almost 25% for both the Richards II design and the Genesis II total knee joint replacement design. The average Von Mises stress in the supracondylar region of interest was similar for both patellofemoral prosthetic designs and the physiological model, with slightly lower stress for the Genesis II design. Conclusions Patellofemoral joint replacement results in periprosthetic stress-shielding, although to a smaller degree than in total knee replacement. Specific patellofemoral prosthetic design properties may result in differences in femoral stress shielding. PMID:22704638

  1. Achieving Student Success in a Regional Public Alternative School Setting through a Consequence-Based Model

    ERIC Educational Resources Information Center

    Burkholder, Sue M.; Merritt, Marti

    2007-01-01

    Genesis Alternative School is a regional, public alternative school setting for middle and high school students from four participating school divisions. It serves 1 rural county school division and 3 small city school divisions. Students are placed at Genesis for disciplinary reasons. Genesis is unique among alternative schools in Virginia…

  2. Scalable and fast heterogeneous molecular simulation with predictive parallelization schemes

    NASA Astrophysics Data System (ADS)

    Guzman, Horacio V.; Junghans, Christoph; Kremer, Kurt; Stuehn, Torsten

    2017-11-01

    Multiscale and inhomogeneous molecular systems are challenging topics in the field of molecular simulation. In particular, modeling biological systems in the context of multiscale simulations and exploring material properties are driving a permanent development of new simulation methods and optimization algorithms. In computational terms, those methods require parallelization schemes that make a productive use of computational resources for each simulation and from its genesis. Here, we introduce the heterogeneous domain decomposition approach, which is a combination of an heterogeneity-sensitive spatial domain decomposition with an a priori rearrangement of subdomain walls. Within this approach, the theoretical modeling and scaling laws for the force computation time are proposed and studied as a function of the number of particles and the spatial resolution ratio. We also show the new approach capabilities, by comparing it to both static domain decomposition algorithms and dynamic load-balancing schemes. Specifically, two representative molecular systems have been simulated and compared to the heterogeneous domain decomposition proposed in this work. These two systems comprise an adaptive resolution simulation of a biomolecule solvated in water and a phase-separated binary Lennard-Jones fluid.

  3. Studies in turbulence

    NASA Technical Reports Server (NTRS)

    Gatski, Thomas B. (Editor); Sarkar, Sutanu (Editor); Speziale, Charles G. (Editor)

    1992-01-01

    Various papers on turbulence are presented. Individual topics addressed include: modeling the dissipation rate in rotating turbulent flows, mapping closures for turbulent mixing and reaction, understanding turbulence in vortex dynamics, models for the structure and dynamics of near-wall turbulence, complexity of turbulence near a wall, proper orthogonal decomposition, propagating structures in wall-bounded turbulence flows. Also discussed are: constitutive relation in compressible turbulence, compressible turbulence and shock waves, direct simulation of compressible turbulence in a shear flow, structural genesis in wall-bounded turbulence flows, vortex lattice structure of turbulent shear slows, etiology of shear layer vortices, trilinear coordinates in fluid mechanics.

  4. Unified thalamic model generates multiple distinct oscillations with state-dependent entrainment by stimulation

    PubMed Central

    2017-01-01

    The thalamus plays a critical role in the genesis of thalamocortical oscillations, yet the underlying mechanisms remain elusive. To understand whether the isolated thalamus can generate multiple distinct oscillations, we developed a biophysical thalamic model to test the hypothesis that generation of and transition between distinct thalamic oscillations can be explained as a function of neuromodulation by acetylcholine (ACh) and norepinephrine (NE) and afferent synaptic excitation. Indeed, the model exhibited four distinct thalamic rhythms (delta, sleep spindle, alpha and gamma oscillations) that span the physiological states corresponding to different arousal levels from deep sleep to focused attention. Our simulation results indicate that generation of these distinct thalamic oscillations is a result of both intrinsic oscillatory cellular properties and specific network connectivity patterns. We then systematically varied the ACh/NE and input levels to generate a complete map of the different oscillatory states and their transitions. Lastly, we applied periodic stimulation to the thalamic network and found that entrainment of thalamic oscillations is highly state-dependent. Our results support the hypothesis that ACh/NE modulation and afferent excitation define thalamic oscillatory states and their response to brain stimulation. Our model proposes a broader and more central role of the thalamus in the genesis of multiple distinct thalamo-cortical rhythms than previously assumed. PMID:29073146

  5. Downscaling CMIP5 climate models shows increased tropical cyclone activity over the 21st century

    PubMed Central

    Emanuel, Kerry A.

    2013-01-01

    A recently developed technique for simulating large [O(104)] numbers of tropical cyclones in climate states described by global gridded data is applied to simulations of historical and future climate states simulated by six Coupled Model Intercomparison Project 5 (CMIP5) global climate models. Tropical cyclones downscaled from the climate of the period 1950–2005 are compared with those of the 21st century in simulations that stipulate that the radiative forcing from greenhouse gases increases by over preindustrial values. In contrast to storms that appear explicitly in most global models, the frequency of downscaled tropical cyclones increases during the 21st century in most locations. The intensity of such storms, as measured by their maximum wind speeds, also increases, in agreement with previous results. Increases in tropical cyclone activity are most prominent in the western North Pacific, but are evident in other regions except for the southwestern Pacific. The increased frequency of events is consistent with increases in a genesis potential index based on monthly mean global model output. These results are compared and contrasted with other inferences concerning the effect of global warming on tropical cyclones. PMID:23836646

  6. Statistical mechanics of protein structural transitions: Insights from the island model

    PubMed Central

    Kobayashi, Yukio

    2016-01-01

    The so-called island model of protein structural transition holds that hydrophobic interactions are the key to both the folding and function of proteins. Herein, the genesis and statistical mechanical basis of the island model of transitions are reviewed, by presenting the results of simulations of such transitions. Elucidating the physicochemical mechanism of protein structural formation is the foundation for understanding the hierarchical structure of life at the microscopic level. Based on the results obtained to date using the island model, remaining problems and future work in the field of protein structures are discussed, referencing Professor Saitô’s views on the hierarchic structure of science. PMID:28409078

  7. Comparison of tropical cyclogenesis processes in climate model and cloud-resolving model simulations using moist static energy budget analysis

    NASA Astrophysics Data System (ADS)

    Wing, Allison; Camargo, Suzana; Sobel, Adam; Kim, Daehyun; Murakami, Hiroyuki; Reed, Kevin; Vecchi, Gabriel; Wehner, Michael; Zarzycki, Colin; Zhao, Ming

    2017-04-01

    In recent years, climate models have improved such that high-resolution simulations are able to reproduce the climatology of tropical cyclone activity with some fidelity and show some skill in seasonal forecasting. However biases remain in many models, motivating a better understanding of what factors control the representation of tropical cyclone activity in climate models. We explore the tropical cyclogenesis processes in five high-resolution climate models, including both coupled and uncoupled configurations. Our analysis framework focuses on how convection, moisture, clouds and related processes are coupled and employs budgets of column moist static energy and the spatial variance of column moist static energy. The latter was originally developed to study the mechanisms of tropical convective organization in idealized cloud-resolving models, and allows us to quantify the different feedback processes responsible for the amplification of moist static energy anomalies associated with the organization of convection and cyclogenesis. We track the formation and evolution of tropical cyclones in the climate model simulations and apply our analysis both along the individual tracks and composited over many tropical cyclones. We then compare the genesis processes; in particular, the role of cloud-radiation interactions, to those of spontaneous tropical cyclogenesis in idealized cloud-resolving model simulations.

  8. Depth profiling analysis of solar wind helium collected in diamond-like carbon film from Genesis

    DOE PAGES

    Bajo, Ken-ichi; Olinger, Chad T.; Jurewicz, Amy J.G.; ...

    2015-01-01

    The distribution of solar-wind ions in Genesis mission collectors, as determined by depth profiling analysis, constrains the physics of ion solid interactions involving the solar wind. Thus, they provide an experimental basis for revealing ancient solar activities represented by solar-wind implants in natural samples. We measured the first depth profile of ⁴He in a collector; the shallow implantation (peaking at <20 nm) required us to use sputtered neutral mass spectrometry with post-photoionization by a strong field. The solar wind He fluence calculated using depth profiling is ~8.5 x 10¹⁴ cm⁻². The shape of the solar wind ⁴He depth profile ismore » consistent with TRIM simulations using the observed ⁴He velocity distribution during the Genesis mission. It is therefore likely that all solar-wind elements heavier than H are completely intact in this Genesis collector and, consequently, the solar particle energy distributions for each element can be calculated from their depth profiles. Ancient solar activities and space weathering of solar system objects could be quantitatively reproduced by solar particle implantation profiles.« less

  9. Scalable and fast heterogeneous molecular simulation with predictive parallelization schemes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Guzman, Horacio V.; Junghans, Christoph; Kremer, Kurt

    Multiscale and inhomogeneous molecular systems are challenging topics in the field of molecular simulation. In particular, modeling biological systems in the context of multiscale simulations and exploring material properties are driving a permanent development of new simulation methods and optimization algorithms. In computational terms, those methods require parallelization schemes that make a productive use of computational resources for each simulation and from its genesis. Here, we introduce the heterogeneous domain decomposition approach, which is a combination of an heterogeneity-sensitive spatial domain decomposition with an a priori rearrangement of subdomain walls. Within this approach and paper, the theoretical modeling and scalingmore » laws for the force computation time are proposed and studied as a function of the number of particles and the spatial resolution ratio. We also show the new approach capabilities, by comparing it to both static domain decomposition algorithms and dynamic load-balancing schemes. Specifically, two representative molecular systems have been simulated and compared to the heterogeneous domain decomposition proposed in this work. Finally, these two systems comprise an adaptive resolution simulation of a biomolecule solvated in water and a phase-separated binary Lennard-Jones fluid.« less

  10. Scalable and fast heterogeneous molecular simulation with predictive parallelization schemes

    DOE PAGES

    Guzman, Horacio V.; Junghans, Christoph; Kremer, Kurt; ...

    2017-11-27

    Multiscale and inhomogeneous molecular systems are challenging topics in the field of molecular simulation. In particular, modeling biological systems in the context of multiscale simulations and exploring material properties are driving a permanent development of new simulation methods and optimization algorithms. In computational terms, those methods require parallelization schemes that make a productive use of computational resources for each simulation and from its genesis. Here, we introduce the heterogeneous domain decomposition approach, which is a combination of an heterogeneity-sensitive spatial domain decomposition with an a priori rearrangement of subdomain walls. Within this approach and paper, the theoretical modeling and scalingmore » laws for the force computation time are proposed and studied as a function of the number of particles and the spatial resolution ratio. We also show the new approach capabilities, by comparing it to both static domain decomposition algorithms and dynamic load-balancing schemes. Specifically, two representative molecular systems have been simulated and compared to the heterogeneous domain decomposition proposed in this work. Finally, these two systems comprise an adaptive resolution simulation of a biomolecule solvated in water and a phase-separated binary Lennard-Jones fluid.« less

  11. European vegetation during Marine Oxygen Isotope Stage-3

    NASA Astrophysics Data System (ADS)

    Huntley, Brian; Alfano, Mary J. o.; Allen, Judy R. M.; Pollard, Dave; Tzedakis, Polychronis C.; de Beaulieu, Jacques-Louis; Grüger, Eberhard; Watts, Bill

    2003-03-01

    European vegetation during representative "warm" and "cold" intervals of stage-3 was inferred from pollen analytical data. The inferred vegetation differs in character and spatial pattern from that of both fully glacial and fully interglacial conditions and exhibits contrasts between warm and cold intervals, consistent with other evidence for stage-3 palaeoenvironmental fluctuations. European vegetation thus appears to have been an integral component of millennial environmental fluctuations during stage-3; vegetation responded to this scale of environmental change and through feedback mechanisms may have had effects upon the environment. The pollen-inferred vegetation was compared with vegetation simulated using the BIOME 3.5 vegetation model for climatic conditions simulated using a regional climate model (RegCM2) nested within a coupled global climate and vegetation model (GENESIS-BIOME). Despite some discrepancies in detail, both approaches capture the principal features of the present vegetation of Europe. The simulated vegetation for stage-3 differs markedly from that inferred from pollen analytical data, implying substantial discrepancy between the simulated climate and that actually prevailing. Sensitivity analyses indicate that the simulated climate is too warm and probably has too short a winter season. These discrepancies may reflect incorrect specification of sea surface temperature or sea-ice conditions and may be exacerbated by vegetation-climate feedback in the coupled global model.

  12. A Genesis Potential Index for Tropical Cyclone by Using Oceanic Parameters

    NASA Astrophysics Data System (ADS)

    Zhou, L.; Zhang, M.; Chen, D.; Wang, C.

    2015-12-01

    This study attempts to create a tropical cyclone (TC) genesis potential index (GPI) by considering oceanic parameters and necessary atmospheric parameters at the sea surface. Based on the general understanding of oceanic impacts on the TC genesis, many candidate factors are evaluated and discriminated, resulting in a new GPI index called GPIocean. GPIocean includes (1) the absolute vorticity at 1000 hPa, (2) the net sea surface longwave radiation, (3) the mean ocean temperature in the upper mixed layer, and (4) the depth of the 26°C isotherm. GPIocean is comparable to the existing GPIs in representing the TC genesis over the western North Pacific on climatological, interannual, and seasonal time scales. In the context of climate change, this new index is expected to be useful for evaluating the oceanic influences on the TC genesis, using ocean reanalysis products and/or climate model outputs.

  13. Simulations of Tornadoes, Tropical Cyclones, MJOs, and QBOs, using GFDL's multi-scale global climate modeling system

    NASA Astrophysics Data System (ADS)

    Lin, Shian-Jiann; Harris, Lucas; Chen, Jan-Huey; Zhao, Ming

    2014-05-01

    A multi-scale High-Resolution Atmosphere Model (HiRAM) is being developed at NOAA/Geophysical Fluid Dynamics Laboratory. The model's dynamical framework is the non-hydrostatic extension of the vertically Lagrangian finite-volume dynamical core (Lin 2004, Monthly Wea. Rev.) constructed on a stretchable (via Schmidt transformation) cubed-sphere grid. Physical parametrizations originally designed for IPCC-type climate predictions are in the process of being modified and made more "scale-aware", in an effort to make the model suitable for multi-scale weather-climate applications, with horizontal resolution ranging from 1 km (near the target high-resolution region) to as low as 400 km (near the antipodal point). One of the main goals of this development is to enable simulation of high impact weather phenomena (such as tornadoes, thunderstorms, category-5 hurricanes) within an IPCC-class climate modeling system previously thought impossible. We will present preliminary results, covering a very wide spectrum of temporal-spatial scales, ranging from simulation of tornado genesis (hours), Madden-Julian Oscillations (intra-seasonal), topical cyclones (seasonal), to Quasi Biennial Oscillations (intra-decadal), using the same global multi-scale modeling system.

  14. CHARMM-GUI 10 Years for Biomolecular Modeling and Simulation

    PubMed Central

    Jo, Sunhwan; Cheng, Xi; Lee, Jumin; Kim, Seonghoon; Park, Sang-Jun; Patel, Dhilon S.; Beaven, Andrew H.; Lee, Kyu Il; Rui, Huan; Roux, Benoît; MacKerell, Alexander D.; Klauda, Jeffrey B.; Qi, Yifei

    2017-01-01

    CHARMM-GUI, http://www.charmm-gui.org, is a web-based graphical user interface that prepares complex biomolecular systems for molecular simulations. CHARMM-GUI creates input files for a number of programs including CHARMM, NAMD, GROMACS, AMBER, GENESIS, LAMMPS, Desmond, OpenMM, and CHARMM/OpenMM. Since its original development in 2006, CHARMM-GUI has been widely adopted for various purposes and now contains a number of different modules designed to set up a broad range of simulations: (1) PDB Reader & Manipulator, Glycan Reader, and Ligand Reader & Modeler for reading and modifying molecules; (2) Quick MD Simulator, Membrane Builder, Nanodisc Builder, HMMM Builder, Monolayer Builder, Micelle Builder, and Hex Phase Builder for building all-atom simulation systems in various environments; (3) PACE CG Builder and Martini Maker for building coarse-grained simulation systems; (4) DEER Facilitator and MDFF/xMDFF Utilizer for experimentally guided simulations; (5) Implicit Solvent Modeler, PBEQ-Solver, and GCMC/BD Ion Simulator for implicit solvent related calculations; (6) Ligand Binder for ligand solvation and binding free energy simulations; and (7) Drude Prepper for preparation of simulations with the CHARMM Drude polarizable force field. Recently, new modules have been integrated into CHARMM-GUI, such as Glycolipid Modeler for generation of various glycolipid structures, and LPS Modeler for generation of lipopolysaccharide structures from various Gram-negative bacteria. These new features together with existing modules are expected to facilitate advanced molecular modeling and simulation thereby leading to an improved understanding of the molecular details of the structure and dynamics of complex biomolecular systems. Here, we briefly review these capabilities and discuss potential future directions in the CHARMM-GUI development project. PMID:27862047

  15. CHARMM-GUI 10 years for biomolecular modeling and simulation.

    PubMed

    Jo, Sunhwan; Cheng, Xi; Lee, Jumin; Kim, Seonghoon; Park, Sang-Jun; Patel, Dhilon S; Beaven, Andrew H; Lee, Kyu Il; Rui, Huan; Park, Soohyung; Lee, Hui Sun; Roux, Benoît; MacKerell, Alexander D; Klauda, Jeffrey B; Qi, Yifei; Im, Wonpil

    2017-06-05

    CHARMM-GUI, http://www.charmm-gui.org, is a web-based graphical user interface that prepares complex biomolecular systems for molecular simulations. CHARMM-GUI creates input files for a number of programs including CHARMM, NAMD, GROMACS, AMBER, GENESIS, LAMMPS, Desmond, OpenMM, and CHARMM/OpenMM. Since its original development in 2006, CHARMM-GUI has been widely adopted for various purposes and now contains a number of different modules designed to set up a broad range of simulations: (1) PDB Reader & Manipulator, Glycan Reader, and Ligand Reader & Modeler for reading and modifying molecules; (2) Quick MD Simulator, Membrane Builder, Nanodisc Builder, HMMM Builder, Monolayer Builder, Micelle Builder, and Hex Phase Builder for building all-atom simulation systems in various environments; (3) PACE CG Builder and Martini Maker for building coarse-grained simulation systems; (4) DEER Facilitator and MDFF/xMDFF Utilizer for experimentally guided simulations; (5) Implicit Solvent Modeler, PBEQ-Solver, and GCMC/BD Ion Simulator for implicit solvent related calculations; (6) Ligand Binder for ligand solvation and binding free energy simulations; and (7) Drude Prepper for preparation of simulations with the CHARMM Drude polarizable force field. Recently, new modules have been integrated into CHARMM-GUI, such as Glycolipid Modeler for generation of various glycolipid structures, and LPS Modeler for generation of lipopolysaccharide structures from various Gram-negative bacteria. These new features together with existing modules are expected to facilitate advanced molecular modeling and simulation thereby leading to an improved understanding of the structure and dynamics of complex biomolecular systems. Here, we briefly review these capabilities and discuss potential future directions in the CHARMM-GUI development project. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  16. Design of the radiation shielding for the time of flight enhanced diagnostics neutron spectrometer at Experimental Advanced Superconducting Tokamak

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Du, T. F.; Chen, Z. J.; Peng, X. Y.

    A radiation shielding has been designed to reduce scattered neutrons and background gamma-rays for the new double-ring Time Of Flight Enhanced Diagnostics (TOFED). The shielding was designed based on simulation with the Monte Carlo code MCNP5. Dedicated model of the EAST tokamak has been developed together with the emission neutron source profile and spectrum; the latter were simulated with the Nubeam and GENESIS codes. Significant reduction of background radiation at the detector can be achieved and this satisfies the requirement of TOFED. The intensities of the scattered and direct neutrons in the line of sight of the TOFED neutron spectrometermore » at EAST are studied for future data interpretation.« less

  17. Multi-dimensional free-electron laser simulation codes : a comparison study.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Biedron, S. G.; Chae, Y. C.; Dejus, R. J.

    A self-amplified spontaneous emission (SASE) free-electron laser (FEL) is under construction at the Advanced Photon Source (APS). Five FEL simulation codes were used in the design phase: GENESIS, GINGER, MEDUSA, RON, and TDA3D. Initial comparisons between each of these independent formulations show good agreement for the parameters of the APS SASE FEL.

  18. Multi-Dimensional Free-Electron Laser Simulation Codes: A Comparison Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nuhn, Heinz-Dieter

    A self-amplified spontaneous emission (SASE) free-electron laser (FEL) is under construction at the Advanced Photon Source (APS). Five FEL simulation codes were used in the design phase: GENESIS, GINGER, MEDUSA, RON, and TDA3D. Initial comparisons between each of these independent formulations show good agreement for the parameters of the APS SASE FEL.

  19. Preterm labor--modeling the uterine electrical activity from cellular level to surface recording.

    PubMed

    Rihana, S; Marque, C

    2008-01-01

    Uterine electrical activity is correlated to the appearance of uterine contractions. forceful contractions appear at the end of term. Therefore, understanding the genesis and the propagation of uterine electrical activity may provide an efficient tool to diagnose preterm labor. Moreover, the control of uterine excitability seems to have important consequences in the control of preterm labor. Modeling the electrical activity in uterine tissue is thus an important step in understanding physiological uterine contractile mechanisms and to permit uterine EMG simulation. Our model presented in this paper, incorporates ion channel models at the cell level, the reaction diffusion equations at the tissue level and the spatiotemporal integration at the uterine EMG reconstructed level. This model validates some key physiological observation hypotheses concerning uterine excitability and propagation.

  20. Understanding the influence of topography on the dynamics of the North American monsoon in climate model simulations

    NASA Astrophysics Data System (ADS)

    Varuolo-Clarke, A. M.; Medeiros, B.; Reed, K. A.

    2017-12-01

    This project examines the influence of topography on the dynamics of the North American monsoon (NAM), including the genesis, peak, and demise of the monsoon. The monsoon season occurs from July to September in the southwestern United States and northwestern Mexico and is characterized by an increase in rainfall that accounts for 40-80% of the total annual rainfall. We use a simple "monsoon index" and show that simulations with the Community Atmosphere model capture the essential nature of the NAM. Comparing standard low-resolution (1o latitude x 1o longitude) simulations where the topography over North America is either retained or removed we evaluate the models' representations of the NAM. To understand the origin of differences between the simulations we analyze the moist static energy budget in the monsoon region. Our preliminary results from simulations with realistic topography indicate that the simulated NAM is driven by locally-generated convection, with advection processes being secondary; this is consistent with the NAM being a result of the thermal contrast between the hot, summertime continent and relatively cool ocean. When topography is removed the simulated NAM will be relatively weak and be driven primarily by locally-generated convection. A better understanding of the monsoon dynamics and the impact topography has on these dynamics will allow for a more accurate representation of the monsoon in projections of future climate.

  1. Dispersion and waves in bounded plasmas with subwavelength inhomogeneities: Genesis of MEFIB

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bhattacharjee, Sudeep

    Bounded plasma exhibit many interesting behavior that are not found in plasmas of 'infinite' extent such as space and astrophysical plasmas. Our studies have revealed that the dispersion properties of waves in a bounded magnetoplasma deviates considerably from the predictions of the Clemmow-Mullaly-Allis (CMA) model, giving rise to new regimes of wave propagation and absorption. The anisotropy of the medium dictated by the length scales of plasma nonuniformity and magnetostatic field inhomogeneity lead to rotation of the polarization axis an effect similar to the Cotton-Mouton effect in a magneto-optic medium but with distinct differences due to wave induced resonances. Thismore » article highlights some of these interesting effects observed experimentally and corroborated with Monte Carlo simulations. One of the principal outcomes of this research is the genesis of a novel multielement focused ion beam (MEFIB) system that utilizes compact bounded plasmas in a minimum – B field to provide intense focused ion beams of a variety of elements for new research in nanoscience and technology.« less

  2. Tropical Cyclone Formation in 30-day Simulation Using Cloud-System-Resolving Global Nonhydrostatic Model (NICAM)

    NASA Astrophysics Data System (ADS)

    Yanase, W.; Satoh, M.; Iga, S.; Tomita, H.

    2007-12-01

    We are developing an icosahedral-grid non-hydrostatic AGCM, which can explicitly represent cumulus or meso-scale convection over the entire globe. We named the model NICAM (Nonhydrostatic ICosahedral Atmospheric Model). On 2005, we have performed a simulations with horizontal grid intervals of 14, 7 and 3.5 km using realistic topography and sea surface temperature in April 2004 (Miura et al., 2007; GRL). It simulated a typhoon Sudal that actually developed over the Northwestern Pacific in 2004. In the present study, the NICAM model with the horizontal grid interval of 14 km was used for perpetual July experiment with 30 forecasting days. In this simulation, several tropical cyclones formed over the wesetern and eastern North Pacific, althought the formation over the western North Pacific occured a little further north to the actually observed region. The mature tropical cyclones with intense wind speed had a structure of a cloud-free eye and eye wall. We have found that the enviromental parameters associated with the tropical cyclone genesis explain well the simulated region of tropical cyclone generation. Over the North Atlantic and eastern North Pacific, westward-moving disturbances like African wave are simulated, which seems to be related to the cyclone formation over the eastern North Pacific. On the other hand, the simulated tropical cyclones over the western North Pacifis seem to form by different factors as has been suggested by the previous studies based on observation. Although the model still has some problems and is under continuous improvement, we can discuss what dynamics is to be represented using a global high-resolution model.

  3. Genesis of mud volcano fluids in the Gulf of Cadiz - A novel model approach

    NASA Astrophysics Data System (ADS)

    Schmidt, Christopher; Burwicz, Ewa; Hensen, Christian; Martínez-Loriente, Sara; Wallmann, Klaus; Gràcia, Eulàlia

    2017-04-01

    Mud volcanism and fluid seepage are common phenomena on the continental margin in the Gulf of Cadiz, North East Atlantic Ocean. Over the past 2 decades more than 50 mud volcanoes have been discovered and investigated interdisciplinarily. Mud volcano fluids emanating at these sites are sourced at great depths and migration is often mediated by strike slip faults in a seismically active region. The geochemical signals of the mud volcano fluids are affected by widespread various processes such as clay mineral dehydration, but also the recrystallization of ancient carbonate rocks and the alteration of oceanic crust have been suggested (Hensen et al., 2015). We developed a novel fully-coupled, basin-scale, reaction-transport model with an adaptive numerical mesh to simulate the fluid genesis in this region. An advantage of this model is the coupling of a realistic geophysical and geochemical approach, considering a growing sediment column over time together with instant compaction of sediments as well as diffusion and advection of dissolved pore water species and chemical reactions. In this proof of concept study, we looked at various scenarios to identify the processes of fluid genesis for 4 mud volcanoes, representing combinations in different subsurface settings. We can reproduce the fluid signatures (chloride, strontium, 87Sr/86Sr) of all mud volcanoes. Furthermore, we can give additional evidence that alteration of oceanic crust by fluid flow is a likely process affecting the fluid composition. Hensen, C., Scholz, F., Nuzzo, M., Valadares, V., Gràcia, E., Terrinha, P., Liebetrau, V., Kaul, N., Silva, S., Martínez-Loriente, S., Bartolome, R., Piñero, E., Magalhães, V. H., Schmidt, M., Weise, S. M., Cunha, M., Hilario, A., Perea, H., Rovelli, L., and Lackschewitz, K., 2015, Strike-slip faults mediate the rise of crustal-derived fluids and mud volcanism in the deep sea: Geology, v. 43, no. 4, p. 339-342.

  4. A genesis potential index for Western North Pacific tropical cyclones by using oceanic parameters

    NASA Astrophysics Data System (ADS)

    Zhang, Min; Zhou, Lei; Chen, Dake; Wang, Chunzai

    2016-09-01

    This study attempts to create a tropical cyclone (TC) genesis potential index (GPI) by considering oceanic parameters and necessary atmospheric parameters. Based on the general understanding of the oceanic impacts on TC genesis, many candidate factors are evaluated and discriminated, resulting in a new GPI index, which is referred to as GPIocean. GPIocean includes the parameters of (1) absolute vorticity at 1000 hPa, (2) net sea surface longwave radiation, (3) mean ocean temperature in the upper mixed layer, and (4) depth of the 26°C isotherm. GPIocean is comparable to existing GPIs in representing TC genesis over the western North Pacific on seasonal and interannual variations. The same procedure can be applied to create a similar GPI for the other ocean basins. In the context of climate change, this new index is expected to be useful for evaluating the oceanic influences on TC genesis by using ocean reanalysis products and climate model outputs.

  5. Coupled heat and fluid flow modeling of the Carboniferous Kuna Basin, Alaska: Implications for the genesis of the Red Dog Pb-Zn-Ag-Ba ore district

    USGS Publications Warehouse

    Garven, G.; Raffensperger, Jeff P.; Dumoulin, Julie A.; Bradley, D.A.; Young, L.E.; Kelley, K.D.; Leach, D.L.

    2003-01-01

    The Red Dog deposit is a giant 175 Mton (16% Zn, 5% Pb), shale-hosted Pb-Zn-Ag-Ba ore district situated in the Carboniferous Kuna Basin, Western Brooks Range, Alaska. These SEDEX-type ores are thought to have formed in calcareous turbidites and black mudstone at elevated sub-seafloor temperatures (120-150??C) within a hydrogeologic framework of submarine convection that was structurally organized by large normal faults. The theory for modeling brine migration and heat transport in the Kuna Basin is discussed with application to evaluating flow patterns and heat transport in faulted rift basins and the effects of buoyancy-driven free convection on reactive flow and ore genesis. Finite element simulations show that hydrothermal fluid was discharged into the Red Dog subbasin during a period of basin-wide crustal heat flow of 150-160 mW/m2. Basinal brines circulated to depths as great as 1-3 km along multiple normal faults flowed laterally through thick clastic aquifers acquiring metals and heat, and then rapidly ascended a single discharge fault zone at rates ??? 5 m/year to mix with seafloor sulfur and precipitate massive sulfide ores. ?? 2003 Elsevier Science B.V. All rights reserved.

  6. Spatial distribution of GRBs and large scale structure of the Universe

    NASA Astrophysics Data System (ADS)

    Bagoly, Zsolt; Rácz, István I.; Balázs, Lajos G.; Tóth, L. Viktor; Horváth, István

    We studied the space distribution of the starburst galaxies from Millennium XXL database at z = 0.82. We examined the starburst distribution in the classical Millennium I (De Lucia et al. (2006)) using a semi-analytical model for the genesis of the galaxies. We simulated a starburst galaxies sample with Markov Chain Monte Carlo method. The connection between the large scale structures homogenous and starburst groups distribution (Kofman and Shandarin 1998), Suhhonenko et al. (2011), Liivamägi et al. (2012), Park et al. (2012), Horvath et al. (2014), Horvath et al. (2015)) on a defined scale were checked too.

  7. Simulate speleogenesis processes with an approach based on fracturing and hydrogeological processes: effect of various hydraulic boundary conditions

    NASA Astrophysics Data System (ADS)

    Lafare, A.; Jourde, H.; Leonardi, V.; Pistre, S.; Dörfliger, N.

    2012-04-01

    Several numerical modeling approaches attempted to simulate the processes of karst conduit genesis. These existing methods are mainly based on the physical and chemical laws driving the carbonate dissolution processes (taking account of calcite saturation of the water and the partial pressure of carbon dioxide). As a consequence, these works bring a well-documented knowledge on the kinetics of the carbonate dissolution processes in karst systems. Nevertheless, these models are mainly applied on simplified initial void networks, which do not match the fracturing and geological reality. Considering that the initial geometry of the void network (fractures, bedding planes) would have an influence on the final pattern of the speleological network, taking account of it could improve the understanding of speleogenesis. In the aim to take into account the geometry of the initial void network (fracture networks of several orders), a numerical model is developed, which involves a pseudo-statistic fracturing generator (REZO3D, Jourde 1999, Josnin et al. 2002, Jourde et al. 2002) coupled to a finite element groundwater simulator (GROUNDWATER, F. Cornaton, CHYN, University of Neuchâtel). The principle of the modeling of the genesis of the karst drainage system is based on an analogical empirical polynomial equation considering the pore velocity and the mean age of the water as main parameters. The computation is carried out on the basis of a time step, whose duration depends on the simulated scenario (from 100 to 5000 years). The mean age of the water is used in order to simulate the decrease of the chemical dissolving potential of the water within the aquifer, in contact with the carbonate rock. The first simulator -REZO3D- allows producing three-dimensional discrete fracture networks constituted by plane fractures, whose spatial distribution respects mechanical and statistical laws. These networks are then processed in order to write finite element meshes which constitute the bases of groundwater flow and transport simulations. The polynomial parameters of the equation are calibrated with former speleogenesis studies (Dreybrodt 1996, Dreybrodt et al. 2005, Palmer 1991). The presented study involves two orthogonal families of fractures embedded in a carbonate matrix, in a mono-stratum setting. For each simulation, several settings of boundary conditions are tested, in terms of recharge (diffuse or concentrated, hydraulic head or flux limited) and discharge (spatial position, punctual or diffuse). The results are interpreted in terms of head fields, mean groundwater age distributions and total flow rates as a function of time. The aim is to assess the influence of the hydraulic boundary conditions on the finally obtained morphologies of the karstic networks, and on the velocity of the evolution of the drainage system. Results are discussed and perspectives are given on the application of such model to real case studies.

  8. Dynamic Stability Testing of the Genesis Sample Return Capsule

    NASA Technical Reports Server (NTRS)

    Cheatwood, F. McNeil; Winchenbach, Gerald L.; Hathaway, Wayne; Chapman, Gary

    2000-01-01

    This paper documents a series of free flight tests of a scale model of the Genesis Sample Return Capsule. These tests were conducted in the Aeroballistic Research Facility (ARF), located at Eglin AFB, FL, during April 1999 and were sponsored by NASA Langley Research Center. Because these blunt atmospheric entry shapes tend to experience small angle of attack dynamic instabilities (frequently leading to limit cycle motions), the primary purpose of the present tests was to determine the dynamic stability characteristics of the Genesis configuration. The tests were conducted over a Mach number range of 1.0 to 4.5. The results for this configuration indicate that the models were dynamically unstable at low angles of attack for all Mach numbers tested. At Mach numbers below 2.5, the models were also unstable at the higher angles of attack (above 15 deg), and motion amplitudes of up to 40 deg were experienced. Above Mach 2.5, the models were dynamically stable at the higher angles of attack.

  9. The GENESIS Mission: Solar Wind Isotopic and Elemental Compositions and Their Implications

    NASA Astrophysics Data System (ADS)

    Wiens, R. C.; Burnett, D. S.; McKeegan, K. D.; Kallio, A. P.; Mao, P. H.; Heber, V. S.; Wieler, R.; Meshik, A.; Hohenberg, C. M.; Mabry, J. C.; Gilmour, J.; Crowther, S. A.; Reisenfeld, D. B.; Jurewicz, A.; Marty, B.; Pepin, R. O.; Barraclough, B. L.; Nordholt, J. E.; Olinger, C. T.; Steinberg, J. T.

    2008-12-01

    The GENESIS mission was a novel NASA experiment to collect solar wind at the Earth's L1 point for two years and return it for analysis. The capsule crashed upon re-entry in 2004, but many of the solar-wind collectors were recovered, including separate samples of coronal hole, interstream, and CME material. Laboratory analyses of these materials have allowed higher isotopic precision than possible with current in-situ detectors. To date GENESIS results have been obtained on isotopes of O, He, Ne, Ar, Kr, and Xe on the order of 1% accuracy and precision, with poorer uncertainty on Xe isotopes and significantly better uncertainties on the lighter noble gases. Elemental abundances are available for the above elements as well as Mg, Si, and Fe. When elemental abundances are compared with other in situ solar wind measurements, agreement is generally quite good. One exception is the Ne elemental abundance, which agrees with Ulysses and Apollo SWC results, but not with ACE. Neon is of particular interest because of the uncertainty in the solar Ne abundance, which has significant implications for the standard solar model. Helium isotopic results of material from the different solar wind regimes collected by GENESIS is consistent with isotopic fractionation predictions of the Coulomb drag model, suggesting that isotopic fractionation corrections need to be applied to heavier elements as well when extrapolating solar wind to solar compositions. Noble gas isotopic compositions from GENESIS are consistent with those obtained for solar wind trapped in lunar grains, but have for the first time yielded a very precise Ar isotopic result. Most interesting for cosmochemistry is a preliminary oxygen isotopic result from GENESIS which indicates a solar enrichment of ~4% in 16O relative to the planets, consistent with a photolytic self-shielding phenomenon during solar system formation. Analyses of solar wind N and C isotopes may further elucidate this phenomenon. Preliminary results from GENESIS have been reported for N, and results are still pending for C.

  10. Numerical modelling of erosion and assimilation of sulfur-rich substrate by martian lava flows: Implications for the genesis of massive sulfide mineralization on Mars

    NASA Astrophysics Data System (ADS)

    Baumgartner, Raphael J.; Baratoux, David; Gaillard, Fabrice; Fiorentini, Marco L.

    2017-11-01

    Mantle-derived volcanic rocks on Mars display physical and chemical commonalities with mafic-ultramafic ferropicrite and komatiite volcanism on the Earth. Terrestrial komatiites are common hosts of massive sulfide mineralization enriched in siderophile-chalcophile precious metals (i.e., Ni, Cu, and the platinum-group elements). These deposits correspond to the batch segregation and accumulation of immiscible sulfide liquids as a consequence of mechanical/thermo-mechanical erosion and assimilation of sulfur-rich bedrock during the turbulent flow of high-temperature and low-viscosity komatiite lava flows. This study adopts this mineralization model and presents numerical simulations of erosion and assimilation of sulfide- and sulfate-rich sedimentary substrates during the dynamic emplacement of (channelled) mafic-ultramafic lava flows on Mars. For sedimentary substrates containing adequate sulfide proportions (e.g., 1 wt% S), our simulations suggest that sulfide supersaturation in low-temperature (< 1350 °C) flows could be attained at < 200 km distance, but may be postponed in high-temperature lavas flows (> 1400 °C). The precious-metals tenor in the derived immiscible sulfide liquids may be significantly upgraded as a result of their prolonged equilibration with large volumes of silicate melts along flow conduits. The influence of sulfate assimilation on sulfide supersaturation in martian lava flows is addressed by simulations of melt-gas equilibration in the Csbnd Hsbnd Osbnd S fluid system. However, prolonged sulfide segregation and deposit genesis by means of sulfate assimilation appears to be limited by lava oxidation and the release of sulfur-rich gas. The identification of massive sulfide endowments on Mars is not possible from remote sensing data. Yet the results of this study aid to define regions for the potential occurrence of such mineral systems, which may be the large canyon systems Noctis Labyrinthus and Valles Marineris, or the Hesperian channel systems of Mars' highlands (e.g., Kasei Valles), most of which have been periodically draped by mafic-ultramafic lavas.

  11. CHARMM-GUI ligand reader and modeler for CHARMM force field generation of small molecules.

    PubMed

    Kim, Seonghoon; Lee, Jumin; Jo, Sunhwan; Brooks, Charles L; Lee, Hui Sun; Im, Wonpil

    2017-06-05

    Reading ligand structures into any simulation program is often nontrivial and time consuming, especially when the force field parameters and/or structure files of the corresponding molecules are not available. To address this problem, we have developed Ligand Reader & Modeler in CHARMM-GUI. Users can upload ligand structure information in various forms (using PDB ID, ligand ID, SMILES, MOL/MOL2/SDF file, or PDB/mmCIF file), and the uploaded structure is displayed on a sketchpad for verification and further modification. Based on the displayed structure, Ligand Reader & Modeler generates the ligand force field parameters and necessary structure files by searching for the ligand in the CHARMM force field library or using the CHARMM general force field (CGenFF). In addition, users can define chemical substitution sites and draw substituents in each site on the sketchpad to generate a set of combinatorial structure files and corresponding force field parameters for throughput or alchemical free energy simulations. Finally, the output from Ligand Reader & Modeler can be used in other CHARMM-GUI modules to build a protein-ligand simulation system for all supported simulation programs, such as CHARMM, NAMD, GROMACS, AMBER, GENESIS, LAMMPS, Desmond, OpenMM, and CHARMM/OpenMM. Ligand Reader & Modeler is available as a functional module of CHARMM-GUI at http://www.charmm-gui.org/input/ligandrm. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  12. Influence of Different Patellofemoral Design Variations Based on Genesis II Total Knee Endoprosthesis on Patellofemoral Pressure and Kinematics.

    PubMed

    Leichtle, Ulf G; Lange, Barbara; Herzog, Yvonne; Schnauffer, Peter; Leichtle, Carmen I; Wülker, Nikolaus; Lorenz, Andrea

    2017-01-01

    In total knee arthroplasty (TKA), patellofemoral groove design varies greatly and likely has a distinct influence on patellofemoral biomechanics. To analyse the selective influence, five patellofemoral design variations were developed based on Genesis II total knee endoprosthesis (original design, being completely flat, being laterally elevated, being medially elevated, and both sides elevated) and made from polyamide using rapid prototyping. Muscle-loaded knee flexion was simulated on 10 human knee specimens using a custom-made knee simulator, measuring the patellofemoral pressure distribution and tibiofemoral and patellofemoral kinematics. The measurements were carried out in the native knee as well as after TKA with the 5 design prototypes. The overall influence of the different designs on the patellofemoral kinematics was small, but we found detectable effects for mediolateral tilt ( p < 0.05 for 35°-80° flexion) and translation of the patella ( p < 0.045 for 20°-65° and 75°-90°), especially for the completely flat design. Considering patellofemoral pressures, major interindividual differences were seen between the designs, which, on average, largely cancelled each other out. These results suggest that the elevation of the lateral margin of the patellofemoral groove is essential for providing mediolateral guidance, but smooth contouring as with original Genesis II design seems to be sufficient. The pronounced interindividual differences identify a need for more patellofemoral design options in TKA.

  13. Fuzzy differential inclusions in atmospheric and medical cybernetics.

    PubMed

    Majumdar, Kausik Kumar; Majumder, Dwijesh Dutta

    2004-04-01

    Uncertainty management in dynamical systems is receiving attention in artificial intelligence, particularly in the fields of qualitative and model based reasoning. Fuzzy dynamical systems occupy a very important position in the class of uncertain systems. It is well established that the fuzzy dynamical systems represented by a set of fuzzy differential inclusions (FDI) are very convenient tools for modeling and simulation of various uncertain systems. In this paper, we discuss about the mathematical modeling of two very complex natural phenomena by means of FDIs. One of them belongs to the atmospheric cybernetics (the term has been used in a broad sense) of the genesis of a cyclonic storm (cyclogenesis), and the other belongs to the bio-medical cybernetics of the evolution of tumor in a human body. Since a discussion of the former already appears in a previous paper by the first author, here, we present very briefly a theoretical formalism of cyclone formation. On the other hand, we treat the latter system more elaborately. We solve the FDIs with the help of an algorithm developed in this paper to numerically simulate the mathematical models. From the simulation results thus obtained, we have drawn a number of interesting conclusions, which have been verified, and this vindicates the validity of our models.

  14. Overview of the Field Phase of the NASA Tropical Cloud Systems and Processes (TCSP)Experiment

    NASA Technical Reports Server (NTRS)

    Hood, Robbie E.; Zipser, Edward; Heymsfield, Gerald M.; Kakar, Ramesh; Halverson Jeffery; Rogers, Robert; Black, Michael

    2006-01-01

    The Tropical Cloud Systems and Processes experiment is sponsored by the National Aeronautics and Space Administration (NASA) to investigate characteristics of tropical cyclone genesis, rapid intensification and rainfall using a three-pronged approach that emphasizes satellite information, suborbital observations and numerical model simulations. Research goals include demonstration and assessment of new technology, improvements to numerical model parameterizations, and advancements in data assimilation techniques. The field phase of the experiment was based in Costa Rica during July 2005. A fully instrumented NASA ER-2 high altitude airplane was deployed with Doppler radar, passive microwave instrumentation, lightning and electric field sensors and an airborne simulator of visible and infrared satellite sensors. Other assets brought to TCSP were a low flying uninhabited aerial vehicle, and a surface-based radiosonde network. In partnership with the Intensity Forecasting Experiment of the National Oceanic and Atmospheric Administration (NOAA) Hurricane Research Division, two NOAA P-3 aircraft instrumented with radar, passive microwave, microphysical, and dropsonde instrumentation were also deployed to Costa Rica. The field phase of TCSP was conducted in Costa Rica to take advantage of the geographically compact tropical cyclone genesis region of the Eastern Pacific Ocean near Central America. However, the unusual 2005 hurricane season provided numerous opportunities to sample tropical cyclone development and intensification in the Caribbean Sea and Gulf of Mexico as well. Development of Hurricane Dennis and Tropical Storm Gert were each investigated over several days in addition to Hurricane Emily as it was close to Saffir-Simpson Category 5 intensity. An overview of the characteristics of these storms along with the pregenesis environment of Tropical Storm Eugene in the Eastern Pacific will be presented.

  15. Large-Scale Controls on Atlantic Tropical Cyclone Activity on Seasonal Time Scales

    NASA Technical Reports Server (NTRS)

    Lim, Young-Kwon; Schubert, Siegfried D.; Reale, Oreste; Molod, Andrea M.; Suarez, Max J.; Auer, Benjamin M.

    2016-01-01

    Interannual variations in seasonal tropical cyclone (TC) activity (e.g., genesis frequency and location, track pattern, and landfall) over the Atlantic are explored by employing observationally-constrained simulations with the NASA Goddard Earth Observing System version (GEOS-5) atmospheric general circulation model. The climate modes investigated are El Nino-Southern Oscillation (ENSO), the North Atlantic Oscillation (NAO), and the Atlantic Meridional Mode (AMM). The results show that the NAO and AMM can strongly modify and even oppose the well- known ENSO impacts, like in 2005, when a strong positive AMM (associated with warm SSTs and a negative SLP anomaly over the western tropical Atlantic), led to a very active TC season with enhanced TC genesis over the Caribbean Sea and a number of landfalls over North America, under a neutral ENSO condition. On the other end, the weak TC activity during 2013 (characterized by weak negative Nio index) appears caused by a NAO-induced positive SLP anomaly with enhanced vertical wind shear over the tropical North Atlantic. During 2010, the combined impact of the three modes produced positive SST anomalies across the entire low-latitudinal Atlantic and a weaker subtropical high, leading to more early recurvers and thus fewer landfalls despite enhanced TC genesis. The study provides evidence that TC number and track are very sensitive to the relative phases and intensities of these three modes, and not just to ENSO alone. Examination of seasonal predictability reveals that predictive skill of the three modes is limited over tropics to sub-tropics, with the AMM having the highest predictability over the North Atlantic, followed by ENSO and NAO.

  16. Testing the Role of p21-Activated Kinases in Schwannoma Formation Using a Novel Genetically Engineered Murine Model that Closely Phenocopies Human NF2 Disease

    DTIC Science & Technology

    2016-06-01

    control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. The major goal of this research project was to genetically and pharmacologically ...with three different pharmacologic PAK inhibitors to determine if targeted PAK inhibition in a preclinical model of schwannoma genesis rescues tumor...this research project was to genetically and pharmacologically test the requirement of Group A PAK signaling in Nf2 deficient schwannoma genesis. We

  17. Towards a Statistical Model of Tropical Cyclone Genesis

    NASA Astrophysics Data System (ADS)

    Fernandez, A.; Kashinath, K.; McAuliffe, J.; Prabhat, M.; Stark, P. B.; Wehner, M. F.

    2017-12-01

    Tropical Cyclones (TCs) are important extreme weather phenomena that have a strong impact on humans. TC forecasts are largely based on global numerical models that produce TC-like features. Aspects of Tropical Cyclones such as their formation/genesis, evolution, intensification and dissipation over land are important and challenging problems in climate science. This study investigates the environmental conditions associated with Tropical Cyclone Genesis (TCG) by testing how accurately a statistical model can predict TCG in the CAM5.1 climate model. TCG events are defined using TECA software @inproceedings{Prabhat2015teca, title={TECA: Petascale Pattern Recognition for Climate Science}, author={Prabhat and Byna, Surendra and Vishwanath, Venkatram and Dart, Eli and Wehner, Michael and Collins, William D}, booktitle={Computer Analysis of Images and Patterns}, pages={426-436}, year={2015}, organization={Springer}} to extract TC trajectories from CAM5.1. L1-regularized logistic regression (L1LR) is applied to the CAM5.1 output. The predictions have nearly perfect accuracy for data not associated with TC tracks and high accuracy differentiating between high vorticity and low vorticity systems. The model's active variables largely correspond to current hypotheses about important factors for TCG, such as wind field patterns and local pressure minima, and suggests new routes for investigation. Furthermore, our model's predictions of TC activity are competitive with the output of an instantaneous version of Emanuel and Nolan's Genesis Potential Index (GPI) @inproceedings{eman04, title = "Tropical cyclone activity and the global climate system", author = "Kerry Emanuel and Nolan, {David S.}", year = "2004", pages = "240-241", booktitle = "26th Conference on Hurricanes and Tropical Meteorology"}.

  18. Simulating the characteristics of tropical cyclones over the South West Indian Ocean using a Stretched-Grid Global Climate Model

    NASA Astrophysics Data System (ADS)

    Maoyi, Molulaqhooa L.; Abiodun, Babatunde J.; Prusa, Joseph M.; Veitch, Jennifer J.

    2018-03-01

    Tropical cyclones (TCs) are one of the most devastating natural phenomena. This study examines the capability of a global climate model with grid stretching (CAM-EULAG, hereafter CEU) in simulating the characteristics of TCs over the South West Indian Ocean (SWIO). In the study, CEU is applied with a variable increment global grid that has a fine horizontal grid resolution (0.5° × 0.5°) over the SWIO and coarser resolution (1° × 1°—2° × 2.25°) over the rest of the globe. The simulation is performed for the 11 years (1999-2010) and validated against the Joint Typhoon Warning Center (JTWC) best track data, global precipitation climatology project (GPCP) satellite data, and ERA-Interim (ERAINT) reanalysis. CEU gives a realistic simulation of the SWIO climate and shows some skill in simulating the spatial distribution of TC genesis locations and tracks over the basin. However, there are some discrepancies between the observed and simulated climatic features over the Mozambique channel (MC). Over MC, CEU simulates a substantial cyclonic feature that produces a higher number of TC than observed. The dynamical structure and intensities of the CEU TCs compare well with observation, though the model struggles to produce TCs with a deep pressure centre as low as the observed. The reanalysis has the same problem. The model captures the monthly variation of TC occurrence well but struggles to reproduce the interannual variation. The results of this study have application in improving and adopting CEU for seasonal forecasting over the SWIO.

  19. The Atlanta Urban Heat Island Mitigation and Air Quality Modeling Project: How High-Resoution Remote Sensing Data Can Improve Air Quality Models

    NASA Technical Reports Server (NTRS)

    Quattrochi, Dale A.; Estes, Maurice G., Jr.; Crosson, William L.; Khan, Maudood N.

    2006-01-01

    The Atlanta Urban Heat Island and Air Quality Project had its genesis in Project ATLANTA (ATlanta Land use Analysis: Temperature and Air quality) that began in 1996. Project ATLANTA examined how high-spatial resolution thermal remote sensing data could be used to derive better measurements of the Urban Heat Island effect over Atlanta. We have explored how these thermal remote sensing, as well as other imaged datasets, can be used to better characterize the urban landscape for improved air quality modeling over the Atlanta area. For the air quality modeling project, the National Land Cover Dataset and the local scale Landpro99 dataset at 30m spatial resolutions have been used to derive land use/land cover characteristics for input into the MM5 mesoscale meteorological model that is one of the foundations for the Community Multiscale Air Quality (CMAQ) model to assess how these data can improve output from CMAQ. Additionally, land use changes to 2030 have been predicted using a Spatial Growth Model (SGM). SGM simulates growth around a region using population, employment and travel demand forecasts. Air quality modeling simulations were conducted using both current and future land cover. Meteorological modeling simulations indicate a 0.5 C increase in daily maximum air temperatures by 2030. Air quality modeling simulations show substantial differences in relative contributions of individual atmospheric pollutant constituents as a result of land cover change. Enhanced boundary layer mixing over the city tends to offset the increase in ozone concentration expected due to higher surface temperatures as a result of urbanization.

  20. GFDL's unified regional-global weather-climate modeling system with variable resolution capability for severe weather predictions and regional climate simulations

    NASA Astrophysics Data System (ADS)

    Lin, S. J.

    2015-12-01

    The NOAA/Geophysical Fluid Dynamics Laboratory has been developing a unified regional-global modeling system with variable resolution capabilities that can be used for severe weather predictions (e.g., tornado outbreak events and cat-5 hurricanes) and ultra-high-resolution (1-km) regional climate simulations within a consistent global modeling framework. The fundation of this flexible regional-global modeling system is the non-hydrostatic extension of the vertically Lagrangian dynamical core (Lin 2004, Monthly Weather Review) known in the community as FV3 (finite-volume on the cubed-sphere). Because of its flexability and computational efficiency, the FV3 is one of the final candidates of NOAA's Next Generation Global Prediction System (NGGPS). We have built into the modeling system a stretched (single) grid capability, a two-way (regional-global) multiple nested grid capability, and the combination of the stretched and two-way nests, so as to make convection-resolving regional climate simulation within a consistent global modeling system feasible using today's High Performance Computing System. One of our main scientific goals is to enable simulations of high impact weather phenomena (such as tornadoes, thunderstorms, category-5 hurricanes) within an IPCC-class climate modeling system previously regarded as impossible. In this presentation I will demonstrate that it is computationally feasible to simulate not only super-cell thunderstorms, but also the subsequent genesis of tornadoes using a global model that was originally designed for century long climate simulations. As a unified weather-climate modeling system, we evaluated the performance of the model with horizontal resolution ranging from 1 km to as low as 200 km. In particular, for downscaling studies, we have developed various tests to ensure that the large-scale circulation within the global varaible resolution system is well simulated while at the same time the small-scale can be accurately captured within the targeted high resolution region.

  1. A numerical modeling study of the physical mechanisms causing radiation to promote the genesis of a tropical cyclone

    NASA Astrophysics Data System (ADS)

    Nicholls, M.; Pielke, R., Sr.; Smith, W. H.; Saleeby, S. M.; Wood, N.

    2016-12-01

    Several cloud-resolving numerical modeling results indicate that radiative forcing significantly accelerates tropical cyclogenesis. The primary mechanism appears to be differential radiative forcing between a relatively cloud-free environment and a developing tropical disturbance that generates circulations that influence convective activity in the core of the system, a mechanism first suggested by Gray and Jacobson. A dynamical perspective of this mechanism is taken by viewing it in terms of the lateral propagation of thermally driven gravity wave circulations. Numerical model experiments indicate that as an expansive stratiform cloud layer forms aloft the long wave cooling is reduced at low and mid levels. During the daytime there is not a very large differential radiative forcing between the environment and the cloud system, but it becomes significant at night when there is strong radiative clear sky cooling of the environment. Thermally driven circulations, are induced characterized by relatively weak subsidence in the environment but considerably stronger upward motion in the system core. This leads to a cooling tendency and increased relative humidity at night which appears to be a major factor in enhancing convective activity thereby leading in the mean to an increased rate of genesis. The increased upward motion and relative humidity that occurs throughout a deep layer is likely to aid in the triggering of convection, and provide a more favorable local environment at mid-levels for maintenance of buoyancy in convective cells due to a reduction of the detrimental effects of dry air entrainment. In order to clarify the effects of radiation the radiative forcing occurring in a fully physics simulation is imposed as a forcing term on the thermodynamic equation in a simulation without microphysics or radiation included to examine the induced circulations and the resultant thermodynamic changes that can influence convective development.

  2. Influence of Different Patellofemoral Design Variations Based on Genesis II Total Knee Endoprosthesis on Patellofemoral Pressure and Kinematics

    PubMed Central

    Lange, Barbara; Herzog, Yvonne; Schnauffer, Peter; Leichtle, Carmen I.; Wülker, Nikolaus

    2017-01-01

    In total knee arthroplasty (TKA), patellofemoral groove design varies greatly and likely has a distinct influence on patellofemoral biomechanics. To analyse the selective influence, five patellofemoral design variations were developed based on Genesis II total knee endoprosthesis (original design, being completely flat, being laterally elevated, being medially elevated, and both sides elevated) and made from polyamide using rapid prototyping. Muscle-loaded knee flexion was simulated on 10 human knee specimens using a custom-made knee simulator, measuring the patellofemoral pressure distribution and tibiofemoral and patellofemoral kinematics. The measurements were carried out in the native knee as well as after TKA with the 5 design prototypes. The overall influence of the different designs on the patellofemoral kinematics was small, but we found detectable effects for mediolateral tilt (p < 0.05 for 35°–80° flexion) and translation of the patella (p < 0.045 for 20°–65° and 75°–90°), especially for the completely flat design. Considering patellofemoral pressures, major interindividual differences were seen between the designs, which, on average, largely cancelled each other out. These results suggest that the elevation of the lateral margin of the patellofemoral groove is essential for providing mediolateral guidance, but smooth contouring as with original Genesis II design seems to be sufficient. The pronounced interindividual differences identify a need for more patellofemoral design options in TKA. PMID:28255225

  3. Impact of Assimilation of Conventional and Satellite Radiance GTS Observations on Simulation of Mesoscale Convective System Over Southeast India Using WRF-3DVar

    NASA Astrophysics Data System (ADS)

    Madhulatha, A.; Rajeevan, M.; Bhowmik, S. K. Roy; Das, A. K.

    2018-01-01

    The primary goal of present study is to investigate the impact of assimilation of conventional and satellite radiance observations in simulating the mesoscale convective system (MCS) formed over south east India. An assimilation methodology based on Weather Research and Forecasting model three dimensional variational data assimilation is considered. Few numerical experiments are carried out to examine the individual and combined impact of conventional and non-conventional (satellite radiance) observations. After the successful inclusion of additional observations, strong analysis increments of temperature and moisture fields are noticed and contributed to significant improvement in model's initial fields. The resulting model simulations are able to successfully reproduce the prominent synoptic features responsible for the initiation of MCS. Among all the experiments, the final experiment in which both conventional and satellite radiance observations assimilated has showed considerable impact on the prediction of MCS. The location, genesis, intensity, propagation and development of rain bands associated with the MCS are simulated reasonably well. The biases of simulated temperature, moisture and wind fields at surface and different pressure levels are reduced. Thermodynamic, dynamic and vertical structure of convective cells associated with the passage of MCS are well captured. Spatial distribution of rainfall is fairly reproduced and comparable to TRMM observations. It is demonstrated that incorporation of conventional and satellite radiance observations improved the local and synoptic representation of temperature, moisture fields from surface to different levels of atmosphere. This study highlights the importance of assimilation of conventional and satellite radiances in improving the models initial conditions and simulation of MCS.

  4. The Genesis of Typhoon Nuri as Observed during the Tropical Cyclone Structure 2008 (TCS-08) Field Experiment - Part 3: Dynamics of Low-Level Spin-Up during the Genesis

    DTIC Science & Technology

    2014-08-27

    are used to perform circula- tion tendency calculations at multiple distances from the low- level circulation center. The results demonstrate a net...the first day of observations. The findings herein strongly support a recent tropical cyclogenesis model posit- ing that the Kelvin cat’s eye...originate and in- tensify. In their observational study, Dunkerton et al. (2009, here- after DMW09) developed a new tropical cyclogenesis model that

  5. Large-scale Controls on Atlantic Tropical Cyclone Activity on Seasonal Time Scales

    PubMed Central

    Lim, Young-Kwon; Schubert, Siegfried D.; Reale, Oreste; Molod, Andrea M.; Suarez, Max J.; Auer, Benjamin M.

    2018-01-01

    Interannual variations in seasonal tropical cyclone (TC) activity (e.g., genesis frequency and location, track pattern, and landfall) over the Atlantic are explored by employing observationally-constrained simulations with the NASA Goddard Earth Observing System version (GEOS-5) atmospheric general circulation model. The climate modes investigated are El Niño-Southern Oscillation (ENSO), the North Atlantic Oscillation (NAO), and the Atlantic Meridional Mode (AMM). The results show that the NAO and AMM can strongly modify and even oppose the well-known ENSO impacts, like in 2005, when a strong positive AMM (associated with warm SSTs and a negative SLP anomaly over the western tropical Atlantic), led to a very active TC season with enhanced TC genesis over the Caribbean Sea and a number of landfalls over North America, under a neutral ENSO condition. On the other end, the weak TC activity during 2013 (characterized by weak negative Niño index) appears caused by a NAO-induced positive SLP anomaly with enhanced vertical wind shear over the tropical North Atlantic. During 2010, the combined impact of the three modes produced positive SST anomalies across the entire low- latitudinal Atlantic and a weaker subtropical high, leading to more early recurvers and thus fewer landfalls despite enhanced TC genesis. The study provides evidence that TC number and track are very sensitive to the relative phases and intensities of these three modes, and not just to ENSO alone. Examination of seasonal predictability reveals that predictive skill of the three modes is limited over tropics to sub-tropics, with the AMM having the highest predictability over the North Atlantic, followed by ENSO and NAO. PMID:29928071

  6. Paleoclimatic signature in terrestrial flood deposits.

    PubMed

    Koltermann, C E; Gorelick, S M

    1992-06-26

    Large-scale process simulation was used to reconstruct the geologic evolution during the past 600,000 years of an alluvial fan in northern California. In order to reproduce the sedimentary record, the simulation accounted for the dynamics of river flooding, sedimentation, subsidence, land movement that resulted from faulting, and sea level changes. Paleoclimatic trends induced fluctuations in stream flows and dominated the development of the sedimentary deposits. The process simulation approach serves as a quantitative means to explore the genesis of sedimentary architecture and its link to past climatic conditions and fault motion.

  7. Open Source GIS based integrated watershed management

    NASA Astrophysics Data System (ADS)

    Byrne, J. M.; Lindsay, J.; Berg, A. A.

    2013-12-01

    Optimal land and water management to address future and current resource stresses and allocation challenges requires the development of state-of-the-art geomatics and hydrological modelling tools. Future hydrological modelling tools should be of high resolution, process based with real-time capability to assess changing resource issues critical to short, medium and long-term enviromental management. The objective here is to merge two renowned, well published resource modeling programs to create an source toolbox for integrated land and water management applications. This work will facilitate a much increased efficiency in land and water resource security, management and planning. Following an 'open-source' philosophy, the tools will be computer platform independent with source code freely available, maximizing knowledge transfer and the global value of the proposed research. The envisioned set of water resource management tools will be housed within 'Whitebox Geospatial Analysis Tools'. Whitebox, is an open-source geographical information system (GIS) developed by Dr. John Lindsay at the University of Guelph. The emphasis of the Whitebox project has been to develop a user-friendly interface for advanced spatial analysis in environmental applications. The plugin architecture of the software is ideal for the tight-integration of spatially distributed models and spatial analysis algorithms such as those contained within the GENESYS suite. Open-source development extends knowledge and technology transfer to a broad range of end-users and builds Canadian capability to address complex resource management problems with better tools and expertise for managers in Canada and around the world. GENESYS (Generate Earth Systems Science input) is an innovative, efficient, high-resolution hydro- and agro-meteorological model for complex terrain watersheds developed under the direction of Dr. James Byrne. GENESYS is an outstanding research and applications tool to address challenging resource management issues in industry, government and nongovernmental agencies. Current research and analysis tools were developed to manage meteorological, climatological, and land and water resource data efficiently at high resolution in space and time. The deliverable for this work is a Whitebox-GENESYS open-source resource management capacity with routines for GIS based watershed management including water in agriculture and food production. We are adding urban water management routines through GENESYS in 2013-15 with an engineering PhD candidate. Both Whitebox-GAT and GENESYS are already well-established tools. The proposed research will combine these products to create an open-source geomatics based water resource management tool that is revolutionary in both capacity and availability to a wide array of Canadian and global users

  8. GENESI-DR: Discovery, Access and on-Demand Processing in Federated Repositories

    NASA Astrophysics Data System (ADS)

    Cossu, Roberto; Pacini, Fabrizio; Parrini, Andrea; Santi, Eliana Li; Fusco, Luigi

    2010-05-01

    GENESI-DR (Ground European Network for Earth Science Interoperations - Digital Repositories) is a European Commission (EC)-funded project, kicked-off early 2008 lead by ESA; partners include Space Agencies (DLR, ASI, CNES), both space and no-space data providers such as ENEA (I), Infoterra (UK), K-SAT (N), NILU (N), JRC (EU) and industry as Elsag Datamat (I), CS (F) and TERRADUE (I). GENESI-DR intends to meet the challenge of facilitating "time to science" from different Earth Science disciplines in discovery, access and use (combining, integrating, processing, …) of historical and recent Earth-related data from space, airborne and in-situ sensors, which are archived in large distributed repositories. In fact, a common dedicated infrastructure such as the GENESI-DR one permits the Earth Science communities to derive objective information and to share knowledge in all environmental sensitive domains over a continuum of time and a variety of geographical scales so addressing urgent challenges such as Global Change. GENESI-DR federates data, information and knowledge for the management of our fragile planet in line with one of the major goals of the many international environmental programmes such as GMES, GEO/GEOSS. As of today, 12 different Digital Repositories hosting more than 60 heterogeneous dataset series are federated in GENESI-DR. Series include satellite data, in situ data, images acquired by airborne sensors, digital elevation models and model outputs. ESA has started providing access to: Category-1 data systematically available on Internet; level 3 data (e.g., GlobCover map, MERIS Global Vegetation Index); ASAR products available in ESA Virtual Archive and related to the Supersites initiatives. In all cases, existing data policies and security constraints are fully respected. GENESI-DR also gives access to Grid and Cloud computing resources allowing authorized users to run a number of different processing services on the available data. The GENESI-DR operational platform is currently being validated against several applications from different domains, such as: automatic orthorectification of SPOT data; SAR Interferometry; GlobModel results visualization and verification by comparison with satellite observations; ozone estimation from ERS-GOME products and comparison with in-situ LIDAR measures; access to ocean-related heterogeneous data and on-the-fly generated products. The project is adopting, ISO 19115, ISO 19139 and OGC standards for geospatial metadata discovery and processing, is compliant with the basis of INSPIRE Implementing Rules for Metadata and Discovery, and uses the OpenSearch protocol with Geo extensions for data and services discovery. OpenSearch is now considered by OGC a mass-market standard to provide machine accessible search interface to data repositories. GENESI-DR is gaining momentum in the Earth Science community thanks to the active participation to the GEO task force "Data Integration and Analysis Systems" and to the several collaborations with EC projects. It is now extending international cooperation agreements specifically with the NASA (Goddard Earth Sciences Data Information Services), with CEODE (the Center of Earth Observation for Digital Earth of Beijing), with the APN (Asia-Pacific Network), with University of Tokyo (Japanese GeoGrid and Data Integration and Analysis System).

  9. Software for Brain Network Simulations: A Comparative Study

    PubMed Central

    Tikidji-Hamburyan, Ruben A.; Narayana, Vikram; Bozkus, Zeki; El-Ghazawi, Tarek A.

    2017-01-01

    Numerical simulations of brain networks are a critical part of our efforts in understanding brain functions under pathological and normal conditions. For several decades, the community has developed many software packages and simulators to accelerate research in computational neuroscience. In this article, we select the three most popular simulators, as determined by the number of models in the ModelDB database, such as NEURON, GENESIS, and BRIAN, and perform an independent evaluation of these simulators. In addition, we study NEST, one of the lead simulators of the Human Brain Project. First, we study them based on one of the most important characteristics, the range of supported models. Our investigation reveals that brain network simulators may be biased toward supporting a specific set of models. However, all simulators tend to expand the supported range of models by providing a universal environment for the computational study of individual neurons and brain networks. Next, our investigations on the characteristics of computational architecture and efficiency indicate that all simulators compile the most computationally intensive procedures into binary code, with the aim of maximizing their computational performance. However, not all simulators provide the simplest method for module development and/or guarantee efficient binary code. Third, a study of their amenability for high-performance computing reveals that NEST can almost transparently map an existing model on a cluster or multicore computer, while NEURON requires code modification if the model developed for a single computer has to be mapped on a computational cluster. Interestingly, parallelization is the weakest characteristic of BRIAN, which provides no support for cluster computations and limited support for multicore computers. Fourth, we identify the level of user support and frequency of usage for all simulators. Finally, we carry out an evaluation using two case studies: a large network with simplified neural and synaptic models and a small network with detailed models. These two case studies allow us to avoid any bias toward a particular software package. The results indicate that BRIAN provides the most concise language for both cases considered. Furthermore, as expected, NEST mostly favors large network models, while NEURON is better suited for detailed models. Overall, the case studies reinforce our general observation that simulators have a bias in the computational performance toward specific types of the brain network models. PMID:28775687

  10. Multi-Constituent Simulation of Thrombus Deposition

    NASA Astrophysics Data System (ADS)

    Wu, Wei-Tao; Jamiolkowski, Megan A.; Wagner, William R.; Aubry, Nadine; Massoudi, Mehrdad; Antaki, James F.

    2017-02-01

    In this paper, we present a spatio-temporal mathematical model for simulating the formation and growth of a thrombus. Blood is treated as a multi-constituent mixture comprised of a linear fluid phase and a thrombus (solid) phase. The transport and reactions of 10 chemical and biological species are incorporated using a system of coupled convection-reaction-diffusion (CRD) equations to represent three processes in thrombus formation: initiation, propagation and stabilization. Computational fluid dynamic (CFD) simulations using the libraries of OpenFOAM were performed for two illustrative benchmark problems: in vivo thrombus growth in an injured blood vessel and in vitro thrombus deposition in micro-channels (1.5 mm × 1.6 mm × 0.1 mm) with small crevices (125 μm × 75 μm and 125 μm × 137 μm). For both problems, the simulated thrombus deposition agreed very well with experimental observations, both spatially and temporally. Based on the success with these two benchmark problems, which have very different flow conditions and biological environments, we believe that the current model will provide useful insight into the genesis of thrombosis in blood-wetted devices, and provide a tool for the design of less thrombogenic devices.

  11. Multi-Constituent Simulation of Thrombus Deposition

    PubMed Central

    Wu, Wei-Tao; Jamiolkowski, Megan A.; Wagner, William R.; Aubry, Nadine; Massoudi, Mehrdad; Antaki, James F.

    2017-01-01

    In this paper, we present a spatio-temporal mathematical model for simulating the formation and growth of a thrombus. Blood is treated as a multi-constituent mixture comprised of a linear fluid phase and a thrombus (solid) phase. The transport and reactions of 10 chemical and biological species are incorporated using a system of coupled convection-reaction-diffusion (CRD) equations to represent three processes in thrombus formation: initiation, propagation and stabilization. Computational fluid dynamic (CFD) simulations using the libraries of OpenFOAM were performed for two illustrative benchmark problems: in vivo thrombus growth in an injured blood vessel and in vitro thrombus deposition in micro-channels (1.5 mm × 1.6 mm × 0.1 mm) with small crevices (125 μm × 75 μm and 125 μm × 137 μm). For both problems, the simulated thrombus deposition agreed very well with experimental observations, both spatially and temporally. Based on the success with these two benchmark problems, which have very different flow conditions and biological environments, we believe that the current model will provide useful insight into the genesis of thrombosis in blood-wetted devices, and provide a tool for the design of less thrombogenic devices. PMID:28218279

  12. Multi-Constituent Simulation of Thrombus Deposition.

    PubMed

    Wu, Wei-Tao; Jamiolkowski, Megan A; Wagner, William R; Aubry, Nadine; Massoudi, Mehrdad; Antaki, James F

    2017-02-20

    In this paper, we present a spatio-temporal mathematical model for simulating the formation and growth of a thrombus. Blood is treated as a multi-constituent mixture comprised of a linear fluid phase and a thrombus (solid) phase. The transport and reactions of 10 chemical and biological species are incorporated using a system of coupled convection-reaction-diffusion (CRD) equations to represent three processes in thrombus formation: initiation, propagation and stabilization. Computational fluid dynamic (CFD) simulations using the libraries of OpenFOAM were performed for two illustrative benchmark problems: in vivo thrombus growth in an injured blood vessel and in vitro thrombus deposition in micro-channels (1.5 mm × 1.6 mm × 0.1 mm) with small crevices (125 μm × 75 μm and 125 μm × 137 μm). For both problems, the simulated thrombus deposition agreed very well with experimental observations, both spatially and temporally. Based on the success with these two benchmark problems, which have very different flow conditions and biological environments, we believe that the current model will provide useful insight into the genesis of thrombosis in blood-wetted devices, and provide a tool for the design of less thrombogenic devices.

  13. DETERMINING THE ELEMENTAL AND ISOTOPIC COMPOSITION OF THE PRESOLAR NEBULA FROM GENESIS DATA ANALYSIS: THE CASE OF OXYGEN.

    PubMed

    Laming, J Martin; Heber, V S; Burnett, D S; Guan, Y; Hervig, R; Huss, G R; Jurewicz, A J G; Koeman-Shields, E C; McKeegan, K D; Nittler, L; Reisenfeld, D B; Rieck, K D; Wang, J; Wiens, R C; Woolum, D S

    2017-12-10

    We compare element and isotopic fractionations measured in solar wind samples collected by NASA's Genesis mission with those predicted from models incorporating both the ponderomotive force in the chromosphere and conservation of the first adiabatic invariant in the low corona. Generally good agreement is found, suggesting that these factors are consistent with the process of solar wind fractionation. Based on bulk wind measurements, we also consider in more detail the isotopic and elemental abundances of O. We find mild support for an O abundance in the range 8.75 - 8.83, with a value as low as 8.69 disfavored. A stronger conclusion must await solar wind regime specific measurements from the Genesis samples.

  14. Modulation of Subseasonal Tropical Cyclone Genesis In The Western North Pacific By Wave Activities

    NASA Astrophysics Data System (ADS)

    Gao, Jianyun; Cheung, Kevin K. W.

    2017-04-01

    Tropical cyclone (TC) activity is well known to possess variability on multiple timescales, ranging from inter-decadal to intraseasonal. In this study, the subseasonal variability of TC genesis in the western North Pacific (WNP) is examined during summer (May-October) for the period of 1979-2015. In particular, clustering of TC activity within subseasonal timescale is the focus. First, three phases (active, normal and inactive phases) of TC clustering are defined based on the statistics of genesis frequency. Then the modes of subseasonal modulation of these three phases by intraseasonal (30-60-day) oscillation (ISO), biweekly (10-20-day) oscillation (BWO), and the convectively coupled equatorial waves (CCEW), including Rossby, Kelvin, and mixed Rossby-gravity and tropical depression-type waves are considered. It is found that the embedding large-scale circulation is significantly different between the inactive phase and the other phases. Further, the intensities and propagation phases of the ISO, BWO and CCEW play different roles to modulate TC genesis frequency during the active and normal phase. Considering the lag correlation of these subseasonal modulation modes and TC genesis, it is possible to construct a statistical model for the purpose of extended-range forecasting of subseasonal variability of TC occurrence over the WNP.

  15. Climatology of Tibetan Plateau Vortices and connection to upper-level flow in reanalysis data and a high-resolution model simulation

    NASA Astrophysics Data System (ADS)

    Curio, Julia; Schiemann, Reinhard; Hodges, Kevin; Turner, Andrew

    2017-04-01

    The Tibetan Plateau (TP) and surrounding high mountain ranges constitute an important forcing of the atmospheric circulation over Asia due to their height and extent. Therefore, the TP impacts weather and climate in downstream regions of East Asia, especially precipitation. Mesoscale Tibetan Plateau Vortices (TPVs) are known to be one of the major precipitation-bearing systems on the TP. They are mainly present at the 500 hPa level and have a vertical extent of 2-3 km while their horizontal scale is around 500 km. Their average lifetime is 18 hours. There are two types of TPVs: the largest number originating and staying on the TP, while a smaller number is able to move off the plateau to the east. The latter category can cause extreme precipitation events and severe flooding in large parts of eastern and southern China downstream of the TP, e.g. the Yangtze River valley. The first aim of the study is to identify and track TPVs in reanalysis data and to connect the TPV activity to the position and strength of the upper-level subtropical jet stream, and to determine favourable conditions for TPV development and maintenance. We identify and track TPVs using the TRACK algorithm developed by Hodges et al. (1994). Relative vorticity at the 500 hPa level from the ERA-Interim and NCEP-CFSR reanalyses are used as input data. TPVs are retained which originate on the TP and which persist for at least two days, since these are more likely to move off the TP to the East. The second aim is to identify TPVs in a high-resolution, present-day climate model simulation of the MetOffice Unified Model (UPSCALE, HadGEM3 GA3.0) to assess how well the model represents the TPV climatology and variability. We find that the reanalysis data sets and the model show similar results for the statistical measures of TPVs (genesis, track, and lysis density). The TPV genesis region is small and stable at a specific region of the TP throughout the year. The reason for this seems to be the convergence of the flow at 500 hPa in the lee of a mountain ridge, which is located directly west of the main genesis region. The strength and position of the subtropical jet stream, shifting from south of the TP in winter to the north in summer, control the distance TPVs can travel eastwards. In the next step we will split the TPVs into two groups, stationary and "moving-off" TPVs, and compare their activity and related atmospheric circulation. Results from these composites may help to answer open research questions on conditions that lead to TPVs moving off the TP, which could help enable better predictions of extreme events in parts of China.

  16. Modeling pedogenesis at multimillennium timescales: achievements and challenges

    NASA Astrophysics Data System (ADS)

    Finke, Peter

    2013-04-01

    The modeling of soil genesis is a particular case of modeling vadose zone processes, because of the variety in processes to be considered and its large (multimillennium) temporal extent. The particular relevancy of pedogenetic modeling for non-pedologists is that it involves the soil compartment carbon cycle. As most of these processes are driven by water flow, modeling hydrological processes is an inevitable component of (non-empirical) modeling of soil genesis. One particular challenge is that both slow and fast pedogenetic processes need to be accounted for. This overview summarizes the state of the art in this new branch of pedology, achievements made so far and current challenges, and is largely based on one particular pedon-scale soil evolution model, SoilGen. SoilGen is essentially a pedon-scale solute transport model that simulates unsaturated water flow, chemical equilibriums of various species with calcite, gypsum and gibbsite as precipitated phases, an exchange phase of Na, K, Ca, Mg, H and Al on clay and organic matter and a solution phase comprising various cations and anions. Additionally, a number of pedogenetic processes are simulated: C-cycling, chemical weathering of primary minerals, physical weathering of soil particles, bioturbation and clay migration. The model was applied onto a climosequence, a chronosequence, a toposequence and as part of a spatio-temporal soilscape reconstruction. Furthermore, the clay migration component has been calibrated and tested and so has the organic matter decomposition component. Quantitative comparisons between simulations and measurements resulted in the identification of possible improvements in the model and associated inputs, identified problems to be solved and identified the current application domain. Major challenges for process-based modeling in the vadose zone at multimillennium timescales can be divided into 4 groups: (i) Reconstruction of initial and boundary conditions; (ii) Accounting for evolution in soil properties such as soil texture and soil structure; (iii) Developing adequate calibration techniques; (iv) Maximizing computational efficiency. Reconstruction of initial and boundary conditions requires multidisciplinary inputs either derived from proxies or from combined vegetation and climate development models. So far, the combination of pedogenetic models and combined vegetation/climate models is rare. At pedogenetic timescales, soil characteristics that are usually considered constant become dynamic: texture, OC, bulk density, precipitated salts, minerals, etc. Interactions and feedbacks between these characteristics and associated hydrological properties need attention, e.g. via pedotransfer functions. The same can be stated for the development of soil structure and associated preferential flow, which is still a challenge. At multimillennium temporal extents, the combination of long model runtime and the fact that most calibration data represent the current stage of soil development requires a special approach. Model performance can be evaluated at various timescales using unconventional proxies. Finally, recognizing the fact that matter redistribution at the landscape scale is of paramount importance at multimillennium extent requires the formulation of computationally efficient 3D models. This will surely involve analysis of the tradeoff between process detail, model accuracy, required boundary inputs and model runtime.

  17. 76 FR 54454 - Issuance of Loan Guarantee to Genesis Solar, LLC, for the Genesis Solar Energy Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    ... DEPARTMENT OF ENERGY Issuance of Loan Guarantee to Genesis Solar, LLC, for the Genesis Solar... Energy Project (GSEP), a 250-megawatt (MW) nominal capacity solar power generating facility on.../Final Environmental Impact Statement for the Genesis Solar Energy Project, Riverside County, California...

  18. Ocean manganese nodules as stromatolite with a fractal like-signature

    NASA Astrophysics Data System (ADS)

    Akai, Junji; Akiyama, Shigeki; Tsuchiyama, Akira; Akai, Kurumi

    Deep-sea manganese (Mn) nodules are problematic in terms of factors such as their characteristic form and genesis. There are many reports of bacterial species from manganese nodules. However, the genesis of these nodules has not been fully confirmed. Samples, mainly from the Clarion Clipperton Fracture zone in the Pacific Ocean, were examined by mineralogical methods and X-ray CT. Thin sections of these samples showed columnar stromatolite structures with rhythmic bands. Mineralized bacteria were observed by SEM and TEM. Surface morphology could be described as having a fractal-like nature. The fractal characteristics of spherical to dome-like forms were fundamentally composed of at least four ranks. The 4th order form corresponds to the stromatolite dome top shapes. Similar granular domain units and porous characteristics in manganese nodules were clearly observed by X-ray CT sections. Mathematical simulation based on fractal models reproduced similar morphological characteristics to the natural samples. So, we arrived at the concluding hypothesis that manganese nodules are aggregated stromatolite with fractal-like characteristics. Furthermore, we discussed the possibility that the nature of the layer manganese oxide minerals as the major component of the nodule and associated Fe-oxyhydroxide minerals may become an absorber/scavenger of strategic heavy metals and also toxic metals in the environments.

  19. Modelling the genesis of equatorial podzols: age and implications for carbon fluxes

    NASA Astrophysics Data System (ADS)

    Doupoux, Cédric; Merdy, Patricia; Régina Montes, Célia; Nunan, Naoise; José Melfi, Adolpho; José Ribeiro Pereira, Osvaldo; Lucas, Yves

    2017-05-01

    Amazonian podzols store huge amounts of carbon and play a key role in transferring organic matter to the Amazon River. In order to better understand their C dynamics, we modelled the formation of representative Amazonian podzol profiles by constraining both total carbon and radiocarbon. We determined the relationships between total carbon and radiocarbon in organic C pools numerically by setting constant C and 14C inputs over time. The model was an effective tool for determining the order of magnitude of the carbon fluxes and the time of genesis of the main carbon-containing horizons, i.e. the topsoil and deep Bh. We performed retrocalculations to take into account the bomb carbon in the young topsoil horizons (calculated apparent 14C age from 62 to 109 years). We modelled four profiles representative of Amazonian podzols, two profiles with an old Bh (calculated apparent 14C age 6.8 × 103 and 8.4 × 103 years) and two profiles with a very old Bh (calculated apparent 14C age 23.2 × 103 and 25.1 × 103 years). The calculated fluxes from the topsoil to the perched water table indicate that the most waterlogged zones of the podzolized areas are the main source of dissolved organic matter found in the river network. It was necessary to consider two Bh carbon pools to accurately represent the carbon fluxes leaving the Bh as observed in previous studies. We found that the genesis time of the studied soils was necessarily longer than 15 × 103 and 130 × 103 years for the two younger and two older Bhs, respectively, and that the genesis time calculated considering the more likely settings runs to around 15 × 103-25 × 103 and 150 × 103-250 × 103 years, respectively.

  20. Determining the Elemental and Isotopic Composition of the Pre-solar Nebula from Genesis Data Analysis: The Case of Oxygen

    DOE PAGES

    Laming, J. Martin; Heber, Veronika S.; Burnett, Donald S.; ...

    2017-12-06

    Here, we compare element and isotopic fractionations measured in bulk solar wind samples collected by NASA's Genesis mission with those predicted from models incorporating both the ponderomotive force in the chromosphere and conservation of the first adiabatic invariant in the low corona. Generally good agreement is found, suggesting that these factors are consistent with the process of solar wind fractionation. Based on bulk wind measurements, we also consider in more detail the isotopic and elemental abundances of O. We also find mild support for an O abundance in the range 8.75–8.83, with a value as low as 8.69 disfavored. Amore » stronger conclusion must await solar wind regime-specific measurements from the Genesis samples.« less

  1. Determining the Elemental and Isotopic Composition of the Pre-solar Nebula from Genesis Data Analysis: The Case of Oxygen

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Laming, J. Martin; Heber, Veronika S.; Burnett, Donald S.

    Here, we compare element and isotopic fractionations measured in bulk solar wind samples collected by NASA's Genesis mission with those predicted from models incorporating both the ponderomotive force in the chromosphere and conservation of the first adiabatic invariant in the low corona. Generally good agreement is found, suggesting that these factors are consistent with the process of solar wind fractionation. Based on bulk wind measurements, we also consider in more detail the isotopic and elemental abundances of O. We also find mild support for an O abundance in the range 8.75–8.83, with a value as low as 8.69 disfavored. Amore » stronger conclusion must await solar wind regime-specific measurements from the Genesis samples.« less

  2. Emerging Concepts About Prenatal Genesis, Aberrant Metabolism and Treatment Paradigms in Polycystic Ovary Syndrome

    PubMed Central

    Witchel, Selma F; Recabarren, Sergio E; Gonzalez, Frank; Diamanti-Kandarakis, Evanthia; Cheang, Kai I; Duleba, Antoni J; Legro, Richard S; Homburg, Roy; Pasquali, Renato; Lobo, Rogerio; Zouboulis, Christos C.; Kelestimur, Fahrettin; Fruzzetti, Franca; Futterweit, Walter; Norman, Robert J; Abbott, David H

    2012-01-01

    The interactive nature of the 8th Annual Meeting of the Androgen Excess & PCOS Society Annual Meeting in Munich, Germany (AEPCOS 2010) and subsequent exchanges between speakers led to emerging concepts in PCOS regarding its genesis, metabolic dysfunction, and clinical treatment of inflammation, metabolic dysfunction, anovulation and hirsutism. Transition of care in congenital adrenal hyperplasia from pediatric to adult providers emerged as a potential model for care transition involving PCOS adolescents. PMID:22661293

  3. Genesis and Evolution of the Skyrme Model from 1954 TO the Present

    NASA Astrophysics Data System (ADS)

    Sanyuk, Valery I.

    Not widely known facts on the genesis of the Skyrme model are presented in a historical survey, based on Skyrme's earliest papers and on his own published remembrance. We consider the evolution of Skyrme's model description of nuclear matter from the "Mesonic Fluid" model up to its final version, known as the baryon model. We pay special tribute to some well-known ideas in contemporary particle physics which one can find in Skyrme's earlier papers, such as: Nuclear Democracy, the Solitonic Mechanism, the Nonlinear Realization of Chiral Symmetry, Topological Charges, Fermi-Bose Transmutations, etc. It is curious to note in the final version of the Skyrme model gleams of Kelvin's "Vortex Atoms" theory. In conclusion we make a brief analysis of the validity of Skyrme's conjectures in view of recent results and pinpoint some questions which still remain.

  4. Is a changing climate affecting the tropical cyclone behavior of Cape Verde?

    NASA Astrophysics Data System (ADS)

    Emmenegger, T. W.; Mann, M. E.; Evans, J. L.

    2016-12-01

    An existing dataset of synthetic tropical cyclone (TC) tracks derived from climate change simulations were used to explore TC variability within a 250 km radius of the Cape Verde Islands (16.5388N, 23.0418W). The synthetic sets were examined according to genesis point location, track projection, intensity, frequency, and seasonality within the observational era (1851 AD to present). These factors of TC variability have been shown to be strongly related to climate oscillations, thus the historical era was grouped by the increasing and decreasing regimes of sea surface temperature (SST) in the main development region (MDR) of the Atlantic Ocean. Numerous studies have examined Atlantic Basin activity throughout this era; the goal of this study is to investigate possible variations in TC behavior around Cape Verde, ultimately determining whether Cape Verde experiences similar fluctuations in activity as observed basin-wide. We find that several facets of TC variability such as intensity, seasonality, and genesis point location around Cape Verde are not significantly different to that of the entire basin, thus forecasts of the entire basin in these respects may also apply to our site. A long-term trend of increasing TC frequency can be identified basin-wide within the observed set, yet activity around Cape Verde does not display this same behavior observably or in any synthetic set. A relationship between the location of genesis points and the regimes of SST fluctuation is shown to be existent. We find both more observed and synthetic genesis points within the vicinity of Cape Verde during cool periods, and an eastward and equatorward shift in cyclogenesis is evident during warm regimes. This southeastern shift in genesis points attributes to the increased intensities of TCs seen during periods of warmer SST. Years of increased SST are additionally linked to an earlier seasonality in Cape Verde.

  5. Influence of sea-ice coverage, sea-surface temperatures and latent heat release on baroclinic instability of an Arctic cyclone

    NASA Astrophysics Data System (ADS)

    Semenov, A.; Zhang, X.

    2012-12-01

    Arctic sea ice has shrunk drastically and Arctic storm activity has intensified over last decades. To improve understanding air-ice-sea interactions in the context of storm activity, we conducted a modeling study of a selected intense storm that invaded and was persistent for prolonged time in the central Arctic Ocean during March 16-22, 2011. A series of control and sensitivity simulations were carried out by employing the Weather Research and Forecasting (WRF) model, which was configured using two nested domains at a resolution of 10 km for the inner domain and 30 km for the outer domain. The control simulations well captured the cyclone genesis, regeneration, track and intensity. Diagnostic analysis and a comparison between the and sensitivity experiments suggest that the strong intensity, regeneration, and long-lasting duration of the cyclone were driven by unusually sustained baroclinic instability, which was resulted due to (1) anomalously reduced sea-ice coverage and strong advection of heat, moisture and vorticity from the North Atlantic; and (2) a release of latent heat due to condensation.

  6. Genesis of Pre-Hurricane Felix (2007). Part 2; Warm Core Formation, Precipitation Evolution, and Predictability

    NASA Technical Reports Server (NTRS)

    Wang, zhuo; Montgomery M. T.; Dunkerton, T. J.

    2010-01-01

    This is the second of a two-part study examining the simulated formation of Atlantic Hurricane Felix (2007) in a cloud-representing framework. Here several open issues are addressed concerning the formation of the storm's warm core, the evolution and respective contribution of stratiform versus convective precipitation within the parent wave's pouch, and the sensitivity of the development pathway reported in Part I to different model physics options and initial conditions. All but one of the experiments include ice microphysics as represented by one of several parameterizations, and the partition of convective versus stratiform precipitation is accomplished using a standard numerical technique based on the high-resolution control experiment. The transition to a warm-core tropical cyclone from an initially cold-core, lower tropospheric wave disturbance is analyzed first. As part of this transformation process, it is shown that deep moist convection is sustained near the pouch center. Both convective and stratiform precipitation rates increase with time. While stratiform precipitation occupies a larger area even at the tropical storm stage, deep moist convection makes a comparable contribution to the total rain rate at the pregenesis stage, and a larger contribution than stratiform processes at the storm stage. The convergence profile averaged near the pouch center is found to become dominantly convective with increasing deep moist convective activity there. Low-level convergence forced by interior diabatic heating plays a key role in forming and intensifying the near-surface closed circulation, while the midlevel convergence associated with stratiform precipitation helps to increase the midlevel circulation and thereby contributes to the formation and upward extension of a tropospheric-deep cyclonic vortex. Sensitivity tests with different model physics options and initial conditions demonstrate a similar pregenesis evolution. These tests suggest that the genesis location of a tropical storm is largely controlled by the parent wave's critical layer, whereas the genesis time and intensity of the protovortex depend on the details of the mesoscale organization, which is less predictable. Some implications of the findings are discussed.

  7. Domain size sensitivities of landfalling eastern Pacific atmospheric rivers

    NASA Astrophysics Data System (ADS)

    McClenny, E. E.; Ullrich, P. A.; Grotjahn, R.; Guan, B.; Waliser, D. E.

    2017-12-01

    Atmospheric rivers (ARs) concentrate a majority of mid-latitude latent heat transport into narrow bands. ARs making landfall along the North American coast typically originate in the waters surrounding Hawaii. We explore here the effects of explicitly simulating this "genesis region" on AR characteristics. We do this using two models and three domains centered on the North American coast. The Weather Research and Forecast (WRF) model, forced by National Center for Environmental Prediction Final Reanalysis data, provides a representative regional model. The simulation domains include: 1. Just off the coastline (100-130W), 2. The coastline to the Pacific just east of Hawaii (100-155W), and 3. The coastline to the Pacific west of Hawaii (100-180W). The Variable Resolution Community Earth System Model simulates ARs while preserving global interactions. In this global model, "domain" refers to the mesh refinement region, each of which corresponds to one of the three previously described WRF domains. We compare ARs from the wet season (October-April) for water years 2009-2017 in the test models against those found in the Modern Era Retrospective Reanalysis 2 (MERRA2). We objectively detect events with the global AR detection algorithm introduced in Guan and Waliser (2015). Comparisons between all model configurations and the reference MERRA2 data will be assessed by characteristics including landfall location (meridional distributions, including quartile ranges and standard deviations of landfalls across the coast), as well as vapor flux and precipitation (in terms of both the contribution of ARs to the larger regional climatology and any differences in the intensity of individual AR events across runs).

  8. Numerical modeling and analysis of the effect of Greek complex topography on tornado genesis

    NASA Astrophysics Data System (ADS)

    Matsangouras, I. T.; Pytharoulis, I.; Nastos, P. T.

    2014-02-01

    Tornadoes have been reported in Greece over the last decades in specific sub-geographical areas and have been associated with strong synoptic forcing. It is well known that meteorological conditions over Greece are affected at various scales by the significant variability of topography, the Ionian Sea at the west and the Aegean Sea at the east. However, there is still uncertainty regarding topography's importance on tornadic generation and development. The aim of this study is to investigate the role of topography in significant tornado genesis events that were triggered under strong synoptic scale forcing over Greece. Three tornado events that occurred over the last years in Thiva (Boeotia, 17 November 2007), Vrastema (Chalkidiki, 12 February 2010) and Vlychos (Lefkada, 20 September 2011) have been selected for numerical experiments. These events were associated with synoptic scale forcing, while their intensity was T4-T5 (Torro scale) and caused significant damage. The simulations were performed using the non-hydrostatic Weather Research and Forecasting model (WRF), initialized with ECMWF gridded analyses, with telescoping nested grids that allow the representation of atmospheric circulations ranging from the synoptic scale down to the meso scale. In the experiments the topography of the inner grid was modified by: (a) 0% (actual topography) and (b) -100% (without topography). The aim was to determine whether the occurrence of tornadoes - mainly identified by various severe weather instability indices - could be indicated by modifying topography. The main utilized instability variables concerned the Bulk Richardson number shear (BRN), the energy helicity index (EHI), the storm-relative environmental helicity (SRH) and the maximum convective available potential energy (MCAPE, for parcel with maximum theta-e). Additional a verification of model was conducted for every sensitivity experiment accompanied with analysis absolute vorticity budget. Numerical simulations revealed that the complex topography was denoted as an important factor during 17 November 2007 and 12 February 2010 events, based on EHI and BRN analyses. Topography around 20 September 2011 event was characterized as the least factor based on EHI, SRH, BRN analyses.

  9. Toward Skillful Subseasonal Prediction of North Atlantic Hurricanes with regionally-refined GFDL HiRAM

    NASA Astrophysics Data System (ADS)

    Gao, K.; Harris, L.; Chen, J. H.; Lin, S. J.

    2017-12-01

    Skillful subseasonal prediction of hurricane activity (from two weeks to less than a season) is important for early preparedness and reducing the hurricane damage in coastal regions. In this study, we will present evaluations of the performance of GFDL HiRAM (High-Resolution Atmospheric Model) for the simulation and prediction of the North Atlantic hurricane activity on the sub-seasonal time scale. A series of sub-seasonal (30-day duration) retrospective predictions were performed over the years 2000-2014 using two configurations of HiRAM: a) global uniform 25km-resolution grid and b) two-way nested grid with a 8km-resolution nest over North Atlantic. The analysis of hurricane structure from the two sets of simulations indicates the two-way-nesting method is an efficient way to improve the representation of hurricanes in global models: the two-way nested configuration produces realistic hurricane inner-core size and structure, which leads to improved lifetime maximum intensity distribution. Both configurations show very promising performance in the subseasonal hurricane genesis prediction, but the two-way nested configuration shows better performance in the prediction of major hurricane (Categories 3-5) activity because of the improved intensity simulation. We will also present the analysis of how the phase and magnitude of MJO, as well as the initial SST anomaly affect the model's prediction skill.

  10. DEMONSTRATION BULLETIN: BIOGENESIS SOIL WASHING TECHNOLOGY - BIOGENESIS

    EPA Science Inventory

    The BioGenesisSM soil washing technology was developed by BioGenesis Enterprises, Inc. to remove organic compounds from soil. The technology uses a proprietary solution (BioGenesisSM cleaner) to transfer organic compounds from the soil matrix to a liquid phase. BioGenesis claims...

  11. EuroGEOSS/GENESIS ``e-Habitat'' AIP-3 Use Scenario

    NASA Astrophysics Data System (ADS)

    Mazzetti, P.; Dubois, G.; Santoro, M.; Peedell, S.; de Longueville, B.; Nativi, S.; Craglia, M.

    2010-12-01

    Natural ecosystems are in rapid decline. Major habitats are disappearing at a speed never observed before. The current rate of species extinction is several orders of magnitude higher than the background rate from the fossil record. Protected Areas (PAs) and Protected Area Systems are designed to conserve natural and cultural resources, to maintain biodiversity (ecosystems, species, genes) and ecosystem services. The scientific challenge of understanding how environmental and climatological factors impact on ecosystems and habitats requires the use of information from different scientific domains. Thus, multidisciplinary interoperability is a crucial requirement for a framework aiming to support scientists. The Group on Earth Observations (or GEO) is coordinating international efforts to build a Global Earth Observation System of Systems (GEOSS). This emerging public infrastructure is interconnecting a diverse and growing array of instruments and systems for monitoring and forecasting changes in the global environment. This “system of systems” supports multidisciplinary and cross-disciplinary scientific researches. The presented GEOSS-based interoperability framework facilitates the discovery and exploitation of datasets and models from heterogeneous scientific domains and Information Technology services (data sources). The GEO Architecture and Data Committee (ADC) launched the Architecture Implementation Pilot (AIP) Initiative to develop and deploy new processes and infrastructure components for the GEOSS Common Infrastructure (GCI) and the broader GEOSS architecture. The current AIP Phase 3 (AIP-3) aims to increase GEOSS capacity to support several strategic Societal Benefit Areas (SBAs) including: Disaster Management, Health/Air Quality, Biodiversity, Energy, Health/Disease and Water. As to Biodiversity, the EC-funded EuroGEOSS (http://www.eurogeoss.eu) and GENESIS (http://www.genesis-fp7.eu) projects have developed a use scenario called “e-Habitat”. This scenario demonstrates how a GEOSS-based interoperability infrastructure can aid decision makers to assess and possibly forecast the irreplaceability of a given protected area, an essential indicator for assessing the criticality of threats this protected area is exposed to. Based on the previous AIP-Phase2 experience, the EuroGEOSS and GENESIS projects enhanced the successfully experimented interoperability infrastructure with: a) a discovery broker service which underpins semantics enabled queries: the EuroGEOSS/GENESIS Discovery Augmentation Component (DAC); b) environmental modeling components (i.e. OGC WPS instances) implementing algorithms to predict evolution of PAs ecosystems; c) a workflow engine to: i) browse semantic repositories; ii) retrieve concepts of interest; iii) search for resources (i.e. datasets and models) related to such concepts; iv) execute WPS instances. This presentation introduces the enhanced infrastructure developed by the EuroGEOSS/GENESIS AIP-3 Pilot to implement the “e-Habitat” use scenario. The presented infrastructure is accessible through the GEO Portal and is going to be used for demonstrating the “e-Habitat” model at the GEO Ministerial Meeting - Beijing, November 2010.

  12. Evaluating the impacts of cumulus, land surface and ocean surface schemes on summertime rainfall simulations over East-to-southeast Asia and the western north Pacific by RegCM4

    NASA Astrophysics Data System (ADS)

    Li, Yu-Bin; Tam, Chi-Yung; Huang, Wan-Ru; Cheung, Kevin K. W.; Gao, Zhiqiu

    2016-04-01

    This study evaluates the sensitivity of summertime rainfall simulations over East-to-southeast Asia and the western north Pacific in the regional climate model version 4 (RegCM4) to cumulus (including Grell with Arakawa-Schubert type closure, Grell with Fritsch-Chappell type closure, and Emanuel), land surface (Biosphere-atmosphere transfer scheme or BATS, and the community land model or CLM) and ocean surface (referred to as Zeng1, Zeng2 and BATS1e in the model) schemes by running the model with different combinations of these parameterization packages. For each of these experiments, ensemble integration of the model was carried out in the extended boreal summer of May-October from 1998 to 2007. The simulated spatial distribution, intensity and inter-annual variation of the precipitation, latent heat flux, position of the subtropical high and tropical cyclone genesis patterns from these numerical experiments were analyzed. Examinations show that the combination of Emanuel, CLM and Zeng2 (E-C-Z2) yields the best overall results, consistent with the fact that physical mechanisms considered in E-C-Z2 tend to be more comprehensive in comparison with the others. Additionally, the rainfall quantity is found very sensitive to sea surface roughness length, and the reduction of the roughness length constant (from 2 × 10-4 to 5 × 10-5 m) in our modified BATS1e mitigates the drastic overestimation of latent heat flux and rainfall, and is therefore preferable to the default value for simulations in the western north Pacific region in RegCM4.

  13. 76 FR 73748 - Genesis Capital, LLC and Northern Lights Fund Trust; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-29

    ... SECURITIES AND EXCHANGE COMMISSION [Investment Company Act Release No. 29867; 812-13935] Genesis Capital, LLC and Northern Lights Fund Trust; Notice of Application November 21, 2011. AGENCY: Securities...: Genesis Capital, LLC (``Genesis Capital'' or the ``Adviser'') and Northern Lights Fund Trust (the ``Trust...

  14. 78 FR 5440 - Ocean Transportation Intermediary License Revocations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-25

    ...: Genesis Forwarding Group USA, Inc. dba Genesis Container Lines. Address: 800 Hindry Avenue, Units B-D...: November 26, 2012. Reason: Failed to maintain a valid bond. License No.: 017663N. Name: Data Cargo Co., Inc... of License. License No.: 020201F. Name: Genesis Forwarding Services CA, Inc. dba Genesis Container...

  15. Relativistic Jets from Collapsars

    NASA Astrophysics Data System (ADS)

    Aloy, M. A.; Müller, E.; Ibáñez, J. M.; Martí, J. M.; MacFadyen, A.

    2000-03-01

    Using a collapsar progenitor model of MacFadyen & Woosley, we have simulated the propagation of an axisymmetric jet through a collapsing rotating massive star with the GENESIS multidimensional relativistic hydrodynamic code. The jet forms as a consequence of an assumed (constant or variable) energy deposition in the range of 1050-1051 ergs s-1 within a 30 deg cone around the rotation axis. The jet flow is strongly beamed (approximately less than a few degrees), spatially inhomogeneous, and time dependent. The jet reaches the surface of the stellar progenitor (R*=2.98x1010 cm) intact. At breakout, the maximum Lorentz factor of the jet flow is 33. After breakout, the jet accelerates into the circumstellar medium, whose density is assumed to decrease exponentially and then become constant, ρext=10-5 g cm-3. Outside the star, the flow begins to expand laterally also (v~c), but the beam remains very well collimated. At a distance of 2.54 R*, where the simulation ends, the Lorentz factor has increased to 44.

  16. Designs and numerical calculations for echo-enabled harmonic generation at very high harmonics

    NASA Astrophysics Data System (ADS)

    Penn, G.; Reinsch, M.

    2011-09-01

    The echo-enabled harmonic generation (EEHG) scheme for driving an FEL using two seeded energy modulations at much longer wavelengths than the output wavelength is a promising concept for future seeded FELs. There are many competing requirements in the design of an EEHG beamline which need careful optimization. Furthermore, revised simulation tools and methods are necessary because of both the high harmonic numbers simulated and the complicated nature of the phase space manipulations which are intrinsic to the scheme. This paper explores the constraints on performance and the required tolerances for reaching wavelengths well below 1/100th of that of the seed lasers, and describes some of the methodology for designing such a beamline. Numerical tools, developed both for the GENESIS and GINGER FEL codes, are presented and used here for more accurate study of the scheme beyond a time-averaged model. In particular, the impact of the local structure in peak current and bunching, which is an inherent part of the EEHG scheme, is evaluated.

  17. Genesis Reentry Observations and Data Analysis

    NASA Technical Reports Server (NTRS)

    Suggs, R. M.; Swift, W. R.

    2005-01-01

    The Genesis spacecraft reentry represented a unique opportunity to observe a "calibrated meteor" from northern Nevada. Knowing its speed, mass, composition, and precise trajectory made it a good subject to test some of the algorithms used to determine meteoroid mass from observed brightness. It was also a good test of an inexpensive set of cameras that could be deployed to observe future shuttle reentries. The utility of consumer-grade video cameras was evident during the STS-107 accident investigation, and the Genesis reentry gave us the opportunity to specify and test commercially available cameras that could be used during future reentries. This Technical Memorandum describes the video observations and their analysis, compares the results with a simple photometric model, describes the forward scatter radar experiment, and lists lessons learned from the expedition and implications for the Stardust reentry in January 2006 as well as future shuttle reentries.

  18. Cancer Theory from Systems Biology Point of View

    NASA Astrophysics Data System (ADS)

    Wang, Gaowei; Tang, Ying; Yuan, Ruoshi; Ao, Ping

    In our previous work, we have proposed a novel cancer theory, endogenous network theory, to understand mechanism underlying cancer genesis and development. Recently, we apply this theory to hepatocellular carcinoma (HCC). A core endogenous network of hepatocyte was established by integrating the current understanding of hepatocyte at molecular level. Quantitative description of the endogenous network consisted of a set of stochastic differential equations which could generate many local attractors with obvious or non-obvious biological functions. By comparing with clinical observation and experimental data, the results showed that two robust attractors from the model reproduced the main known features of normal hepatocyte and cancerous hepatocyte respectively at both modular and molecular level. In light of our theory, the genesis and progression of cancer is viewed as transition from normal attractor to HCC attractor. A set of new insights on understanding cancer genesis and progression, and on strategies for cancer prevention, cure, and care were provided.

  19. Metamorphic sole genesis at the base of ophiolite nappes: Insights from numerical models

    NASA Astrophysics Data System (ADS)

    Yamato, Philippe; Agard, Philippe; Duretz, Thibault

    2015-04-01

    Obduction emplaces oceanic lithosphere on top of continental lithosphere. Although a number of studies have focused on this enigmatic process, the initial stages of obduction remain poorly understood. Field, petrological, and geochronological data reveal that during the first stages of the obduction (i.e., during the first 1-2 Myrs) a HT-LP metamorphic sole (~700-800 ° C and ~1 GPa) is systematically welded at the base of ophiolite nappes. However, the reason why such welding of the ophiolite soles occurs at these particular P-T conditions, and only at the onset of obduction, is still an open issue. The aim of this study is to explore the conditions required to explain the genesis of metamorphic soles. For this, we employ two-dimensional numerical modelling, constrained by the wealth of available data from the Oman ophiolite. We first present a thermo-kinematic model in which the velocity field is prescribed in order to simulate obduction initiation. The heat advection-diffusion equation is solved at each time step. The model is intentionally kept simple in order to control each parameter (e.g., convergence rate, dip angle, thermal age) and to test its influence on the resulting P-T conditions obtained through time along the obduction interface. Results show that the key factor allowing the formation of metamorphic soles is the age of the oceanic lithosphere involved. Moreover, we speculate that the reason why metamorphic soles are always welded at the same P-T conditions is due to the fact that, at these particular conditions, strength jumps occur within the oceanic lithosphere. These jumps lead to changes in strain localisation and allow the spalling of oceanic crust and its juxtaposition to the ophiolite nappe. This hypothesis is further tested using thermo-mechanical models in which the obduction initiates dynamically (only initial and boundary conditions are prescribed). The interplay between the temperature evolution and the mechanical behaviour is then discussed.

  20. GENESIS: new self-consistent models of exoplanetary spectra

    NASA Astrophysics Data System (ADS)

    Gandhi, Siddharth; Madhusudhan, Nikku

    2017-12-01

    We are entering the era of high-precision and high-resolution spectroscopy of exoplanets. Such observations herald the need for robust self-consistent spectral models of exoplanetary atmospheres to investigate intricate atmospheric processes and to make observable predictions. Spectral models of plane-parallel exoplanetary atmospheres exist, mostly adapted from other astrophysical applications, with different levels of sophistication and accuracy. There is a growing need for a new generation of models custom-built for exoplanets and incorporating state-of-the-art numerical methods and opacities. The present work is a step in this direction. Here we introduce GENESIS, a plane-parallel, self-consistent, line-by-line exoplanetary atmospheric modelling code that includes (a) formal solution of radiative transfer using the Feautrier method, (b) radiative-convective equilibrium with temperature correction based on the Rybicki linearization scheme, (c) latest absorption cross-sections, and (d) internal flux and external irradiation, under the assumptions of hydrostatic equilibrium, local thermodynamic equilibrium and thermochemical equilibrium. We demonstrate the code here with cloud-free models of giant exoplanetary atmospheres over a range of equilibrium temperatures, metallicities, C/O ratios and spanning non-irradiated and irradiated planets, with and without thermal inversions. We provide the community with theoretical emergent spectra and pressure-temperature profiles over this range, along with those for several known hot Jupiters. The code can generate self-consistent spectra at high resolution and has the potential to be integrated into general circulation and non-equilibrium chemistry models as it is optimized for efficiency and convergence. GENESIS paves the way for high-fidelity remote sensing of exoplanetary atmospheres at high resolution with current and upcoming observations.

  1. Resolving Low-Density Lipoprotein (LDL) on the Human Aortic Surface Using Large Eddy Simulation

    NASA Astrophysics Data System (ADS)

    Lantz, Jonas; Karlsson, Matts

    2011-11-01

    The prediction and understanding of the genesis of vascular diseases is one of the grand challenges in biofluid engineering. The progression of atherosclerosis is correlated to the build- up of LDL on the arterial surface, which is affected by the blood flow. A multi-physics simulation of LDL mass transport in the blood and through the arterial wall of a subject specific human aorta was performed, employing a LES turbulence model to resolve the turbulent flow. Geometry and velocity measurements from magnetic resonance imaging (MRI) were incorporated to assure physiological relevance of the simulation. Due to the turbulent nature of the flow, consecutive cardiac cycles are not identical, neither in vivo nor in the simulations. A phase average based on a large number of cardiac cycles is therefore computed, which is the proper way to get reliable statistical results from a LES simulation. In total, 50 cardiac cycles were simulated, yielding over 2.5 Billion data points to be post-processed. An inverse relation between LDL and WSS was found; LDL accumulated on locations where WSS was low and vice-versa. Large temporal differences were present, with the concentration level decreasing during systolic acceleration and increasing during the deceleration phase. This method makes it possible to resolve the localization of LDL accumulation in the normal human aorta with its complex transitional flow.

  2. 75 FR 69458 - Notice of Availability of the Record of Decision for the Genesis Solar Energy Project and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-12

    ..., LVRWB09B2520] Notice of Availability of the Record of Decision for the Genesis Solar Energy Project [email protected] . SUPPLEMENTARY INFORMATION: Genesis Solar, LLC, a wholly owned subsidiary of NextEra Energy Resources, filed right-of-way (ROW) application CACA-048880 for the proposed Genesis Solar Energy...

  3. Seasonal prediction of the typhoon genesis frequency over the Western North Pacific with a Poisson regression model

    NASA Astrophysics Data System (ADS)

    Zhang, Xinchang; Zhong, Shanshan; Wu, Zhiwei; Li, Yun

    2017-06-01

    This study investigates the typhoon genesis frequency (TGF) in the dominant season (July to October) in Western North Pacific (WNP) using observed data in 1965-2015. Of particular interest is the predictability of the TGF and associated preseason sea surface temperature (SST) in the Pacific. It is found that, the TGF is positively related to a tri-polar pattern of April SST anomalies in North Pacific (NP{T}_{Apr}), while it is negatively related to SST anomalies over the Coral Sea (CSS{T}_{Apr}) off east coast of Australia. The NP{T}_{Apr} leads to large anomalous cyclonic circulation over North Pacific. The anomalous southwesterly weakens the northeast trade wind, decreases evaporation, and induces warm water in central tropical North Pacific. As such, the warming effect amplifies the temperature gradient in central tropical North Pacific, which in turn maintains the cyclonic wind anomaly in the west tropical Pacific, which favors the typhoon genesis in WNP. In the South Pacific, the CSS{T}_{Apr} supports the typhoon formation over the WNP by (a) strengthening the cross-equatorial flows and enhancing the Inter-tropical Convergence Zone; (b) weakening southeast and northeast trade wind, and keeping continuous warming in the center of tropical Pacific. The influence of both NP{T}_{Apr} and CSS{T}_{Apr} can persistently affect the zonal wind in the tropical Pacific and induce conditions favorable for the typhoon genesis in the typhoon season. A Poisson regression model using NP{T}_{Apr} and CSS}{T}_{Apr} is developed to predict the TGF and a promising skill is achieved.

  4. Predicting Tropical Cyclogenesis with a Global Mesoscale Model: Hierarchical Multiscale Interactions During the Formation of Tropical Cyclone Nargis(2008)

    NASA Technical Reports Server (NTRS)

    Shen, B.-W.; Tao, W.-K.; Lau, W. K.; Atlas, R.

    2010-01-01

    Very severe cyclonic storm Nargis devastated Burma (Myanmar) in May 2008, caused tremendous damage and numerous fatalities, and became one of the 10 deadliest tropical cyclones (TCs) of all time. To increase the warning time in order to save lives and reduce economic damage, it is important to extend the lead time in the prediction of TCs like Nargis. As recent advances in high-resolution global models and supercomputing technology have shown the potential for improving TC track and intensity forecasts, the ability of a global mesoscale model to predict TC genesis in the Indian Ocean is examined in this study with the aim of improving simulations of TC climate. High-resolution global simulations with real data show that the initial formation and intensity variations of TC Nargis can be realistically predicted up to 5 days in advance. Preliminary analysis suggests that improved representations of the following environmental conditions and their hierarchical multiscale interactions were the key to achieving this lead time: (1) a westerly wind burst and equatorial trough, (2) an enhanced monsoon circulation with a zero wind shear line, (3) good upper-level outflow with anti-cyclonic wind shear between 200 and 850 hPa, and (4) low-level moisture convergence.

  5. 33 CFR 147.825 - Chevron Genesis Spar safety zone.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Chevron Genesis Spar safety zone... (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES SAFETY ZONES § 147.825 Chevron Genesis Spar safety zone. (a) Description. The Chevron Genesis Spar, Green Canyon 205A (GC205A), is located at position 27°46′46.365″ N, 90...

  6. 33 CFR 147.825 - Chevron Genesis Spar safety zone.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Chevron Genesis Spar safety zone... (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES SAFETY ZONES § 147.825 Chevron Genesis Spar safety zone. (a) Description. The Chevron Genesis Spar, Green Canyon 205A (GC205A), is located at position 27°46′46.365″ N, 90...

  7. 33 CFR 147.825 - Chevron Genesis Spar safety zone.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Chevron Genesis Spar safety zone... (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES SAFETY ZONES § 147.825 Chevron Genesis Spar safety zone. (a) Description. The Chevron Genesis Spar, Green Canyon 205A (GC205A), is located at position 27°46′46.365″ N, 90...

  8. 33 CFR 147.825 - Chevron Genesis Spar safety zone.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Chevron Genesis Spar safety zone... (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES SAFETY ZONES § 147.825 Chevron Genesis Spar safety zone. (a) Description. The Chevron Genesis Spar, Green Canyon 205A (GC205A), is located at position 27°46′46.365″ N, 90...

  9. Computational Systems Biology in Cancer: Modeling Methods and Applications

    PubMed Central

    Materi, Wayne; Wishart, David S.

    2007-01-01

    In recent years it has become clear that carcinogenesis is a complex process, both at the molecular and cellular levels. Understanding the origins, growth and spread of cancer, therefore requires an integrated or system-wide approach. Computational systems biology is an emerging sub-discipline in systems biology that utilizes the wealth of data from genomic, proteomic and metabolomic studies to build computer simulations of intra and intercellular processes. Several useful descriptive and predictive models of the origin, growth and spread of cancers have been developed in an effort to better understand the disease and potential therapeutic approaches. In this review we describe and assess the practical and theoretical underpinnings of commonly-used modeling approaches, including ordinary and partial differential equations, petri nets, cellular automata, agent based models and hybrid systems. A number of computer-based formalisms have been implemented to improve the accessibility of the various approaches to researchers whose primary interest lies outside of model development. We discuss several of these and describe how they have led to novel insights into tumor genesis, growth, apoptosis, vascularization and therapy. PMID:19936081

  10. Towards a unified Global Weather-Climate Prediction System

    NASA Astrophysics Data System (ADS)

    Lin, S. J.

    2016-12-01

    The Geophysical Fluid Dynamics Laboratory has been developing a unified regional-global modeling system with variable resolution capabilities that can be used for severe weather predictions and kilometer scale regional climate simulations within a unified global modeling system. The foundation of this flexible modeling system is the nonhydrostatic Finite-Volume Dynamical Core on the Cubed-Sphere (FV3). A unique aspect of FV3 is that it is "vertically Lagrangian" (Lin 2004), essentially reducing the equation sets to two dimensions, and is the single most important reason why FV3 outperforms other non-hydrostatic cores. Owning to its accuracy, adaptability, and computational efficiency, the FV3 has been selected as the "engine" for NOAA's Next Generation Global Prediction System (NGGPS). We have built into the modeling system a stretched grid, a two-way regional-global nested grid, and an optimal combination of the stretched and two-way nests capability, making kilometer-scale regional simulations within a global modeling system feasible. Our main scientific goal is to enable simulations of high impact weather phenomena (such as tornadoes, thunderstorms, category-5 hurricanes) within an IPCC-class climate modeling system previously regarded as impossible. In this presentation I will demonstrate that, with the FV3, it is computationally feasible to simulate not only super-cell thunderstorms, but also the subsequent genesis of tornado-like vortices using a global model that was originally designed for climate simulations. The development and tuning strategy between traditional weather and climate models are fundamentally different due to different metrics. We were able to adapt and use traditional "climate" metrics or standards, such as angular momentum conservation, energy conservation, and flux balance at top of the atmosphere, and gain insight into problems of traditional weather prediction model for medium-range weather prediction, and vice versa. Therefore, the unification in weather and climate models can happen not just at the algorithm or parameterization level, but also in the metric and tuning strategy used for both applications, and ultimately, with benefits to both weather and climate applications.

  11. Molecular Substrate Alteration by Solar Wind Radiation Documented on Flown Genesis Mission Array Materials

    NASA Technical Reports Server (NTRS)

    Calaway, Michael J.; Stansbery, Eileen K.

    2006-01-01

    The Genesis spacecraft sampling arrays were exposed to various regimes of solar wind during flight that included: 313.01 days of high-speed wind from coronal holes, 335.19 days of low-speed inter-stream wind, 191.79 days of coronal mass ejections, and 852.83 days of bulk solar wind at Lagrange 1 orbit. Ellipsometry measurements taken at NASA s Johnson Space Center show that all nine flown array materials from the four Genesis regimes have been altered by solar wind exposure during flight. These measurements show significant changes in the optical constant for all nine ultra-pure materials that flew on Genesis when compared with their non-flight material standard. This change in the optical constant (n and k) of the material suggests that the molecular structure of the all nine ultra-pure materials have been altered by solar radiation. In addition, 50 samples of float-zone and czochralski silicon bulk array ellipsometry results were modeled with an effective medium approximation layer (EMA substrate layer) revealing a solar radiation molecular damage zone depth below the SiO2 native oxide layer ranging from 392 to 613 . This bulk solar wind radiation penetration depth is comparable to the depth of solar wind implantation depth of Mg measured by SIMS and SARISA.

  12. The quantum matrix and information from the hydrocarbon oil molecule

    NASA Astrophysics Data System (ADS)

    Seyful-Mulyukov, R. B.

    2016-03-01

    The quantum matrix of the hydrocarbon (HC) molecule is substantiated. On the basis of its properties and behavior, the genesis of oil is explained as a process of self-evolution of oil and preservation of molecules of different composition and generation time. Individual HC molecules are generated in nanoseconds, and the period of the genesis of oil is comparable with that of migration of the HC fluid from the mantle to the deposit. A model of subatomic abiogenic genesis of oil is presented. Hydrocarbon (HC) molecules of various structure and composition are formed due to interaction of the valency electron orbitals of C and H atoms, the elemental particles of which are quantum objects and carriers of information. On the basis of this, the term quantum matrix of the HC molecule, the properties and behavior of which explain the genesis of oil as a process of its self-evolution and preservation of the molecules of various composition and the period of generation of oil, is substantiated. It is proved that individual HC molecules are generated within nanoseconds and the period of origin of the entire assemblage of more than 500 molecules of oil of various types is comparable with the period of migration of the HC fluid from the mantle to the deposit.

  13. Cutting of Gold Foil in the Genesis Laboratory

    NASA Image and Video Library

    2005-02-15

    The facility for storing and examining Genesis solar wind samples consists of two adjacent laboratories. In these laboratories, the cutting of gold foil to be used in the gathering of the solar wind dust aboard the Genesis spacecraft. Views include: The process of cutting gold foil to be used aboard the Genesis spacecraft. The technicians use Gore-Tex suits with filters as to not contaminate the items.

  14. Helium, neon, and argon composition of the solar wind as recorded in gold and other Genesis collector materials

    NASA Astrophysics Data System (ADS)

    Pepin, Robert O.; Schlutter, Dennis J.; Becker, Richard H.; Reisenfeld, Daniel B.

    2012-07-01

    We report compositions and fluxes of light noble gases in the solar wind (SW), extracted by stepped pyrolysis and amalgamation from gold collector materials carried on the Genesis Solar Wind Sample Return Mission. Results are compared with data from other laboratories on SW-He, Ne and Ar distributions implanted in Genesis aluminum, carbon, and silicon collectors and extracted by laser ablation. Corrections for mass-dependent losses (“backscatter”) of impinging SW ions due to scattering from the collector material are substantially larger for gold than for these lower atomic weight targets. We assess such losses by SRIM simulation calculations of SW backscatter from gold which are applied to the measurements to recover the composition of the incident SW. Averaged results of integrated stepped pyrolysis and single-step amalgamation measurements, with 1σ errors, are as follows: for SW-Ne and Ar isotope ratios (3He/4He was not measured), 20Ne/22Ne = 14.001 ± 0.042, 21Ne/22Ne = 0.03361 ± 0.00018, 36Ar/38Ar = 5.501 ± 0.014; for SW element ratios, 4He/20Ne = 641 ± 15, 20Ne/36Ar = 51.6 ± 0.5; and for SW fluxes in atoms cm-2 s-1 at the Genesis L1 station, 4He = 1.14 ± 0.04 × 107, 20Ne = 1.80 ± 0.06 × 104, 36Ar = 3.58 ± 0.11 × 102. Except for the 21Ne/22Ne and 20Ne/36Ar ratios, these values are in reasonable accord (within ∼1-3σ) with measurements on different collector materials reported by one or both of two other Genesis noble gas research groups. We further find, in three stepped pyrolysis experiments on gold foil, that He, Ne and Ar are released at increasing temperatures without elemental fractionation, in contrast to a pyrolytic extraction of a single non-gold collector (Al) where the release patterns point to mass-dependent thermal diffusion. The pyrolyzed gold foils exhibit enhancements, relative to sample totals, in 20Ne/22Ne and 21Ne/22Ne ratios evolved at low temperatures. The absence of elemental fractionation in pyrolytic release from gold implies that these isotope ratio enhancements, involving much smaller mass differences, do not result from preferential diffusive release of the lighter Ne isotopes. This effect, not predicted by SRIM calculations, has also been observed in stepped acid-etch releases from a different Genesis collector material in another laboratory.

  15. Evolution of Mesoscale Convective System over the South Western Peninsular India: Observations from Microwave Radiometer and Simulations using WRF

    NASA Astrophysics Data System (ADS)

    Uma, K. N.; Krishna Moorthy, K.; Sijikumar, S.; Renju, R.; Tinu, K. A.; Raju, Suresh C.

    2012-07-01

    Meso-scale Convective Systems (MCS) are important in view of their large cumulous build-up, vertical extent, short horizontal extent and associated thundershowers. The Microwave Radiometer Profiler (MRP) over the equatorial coastal station Thiruvanathapuram (Trivandrum, 8.55oN, 76.9oE), has been utilized to understand the genesis of Mesoscale convective system (MCS), that occur frequently during the pre-monsoon season. Examination of the measurement of relative humidity, temperature and cloud liquid water measurements, over the zenith and two scanning elevation angles (15o) viewing both over the land and the sea respectively revealed that the MCS generally originate over the land during early afternoon hours, propagate seawards over the observational site and finally dissipate over the sea, with accompanying rainfall and latent heat release. The simulations obtained using Advanced Research-Weather Research and Forecast (WRF-ARW) model effectively reproduces the thermodynamical and microphysical properties of the MCS. The time duration and quantity of rainfall obtained by the simulations also well compared with the observations. Analysis also suggests that wind shear in the upper troposphere is responsible for the growth and the shape of the convective cloud.

  16. Modeling and simulation of blast-induced, early-time intracranial wave physics leading to traumatic brain injury.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ford, Corey C.; Taylor, Paul Allen

    The objective of this modeling and simulation study was to establish the role of stress wave interactions in the genesis of traumatic brain injury (TBI) from exposure to explosive blast. A high resolution (1 mm{sup 3} voxels), 5 material model of the human head was created by segmentation of color cryosections from the Visible Human Female dataset. Tissue material properties were assigned from literature values. The model was inserted into the shock physics wave code, CTH, and subjected to a simulated blast wave of 1.3 MPa (13 bars) peak pressure from anterior, posterior and lateral directions. Three dimensional plots ofmore » maximum pressure, volumetric tension, and deviatoric (shear) stress demonstrated significant differences related to the incident blast geometry. In particular, the calculations revealed focal brain regions of elevated pressure and deviatoric (shear) stress within the first 2 milliseconds of blast exposure. Calculated maximum levels of 15 KPa deviatoric, 3.3 MPa pressure, and 0.8 MPa volumetric tension were observed before the onset of significant head accelerations. Over a 2 msec time course, the head model moved only 1 mm in response to the blast loading. Doubling the blast strength changed the resulting intracranial stress magnitudes but not their distribution. We conclude that stress localization, due to early time wave interactions, may contribute to the development of multifocal axonal injury underlying TBI. We propose that a contribution to traumatic brain injury from blast exposure, and most likely blunt impact, can occur on a time scale shorter than previous model predictions and before the onset of linear or rotational accelerations traditionally associated with the development of TBI.« less

  17. Is the poleward migration of tropical cyclone maximum intensity associated with a poleward migration of tropical cyclone genesis?

    NASA Astrophysics Data System (ADS)

    Daloz, Anne Sophie; Camargo, Suzana J.

    2018-01-01

    A recent study showed that the global average latitude where tropical cyclones achieve their lifetime-maximum intensity has been migrating poleward at a rate of about one-half degree of latitude per decade over the last 30 years in each hemisphere. However, it does not answer a critical question: is the poleward migration of tropical cyclone lifetime-maximum intensity associated with a poleward migration of tropical cyclone genesis? In this study we will examine this question. First we analyze changes in the environmental variables associated with tropical cyclone genesis, namely entropy deficit, potential intensity, vertical wind shear, vorticity, skin temperature and specific humidity at 500 hPa in reanalysis datasets between 1980 and 2013. Then, a selection of these variables is combined into two tropical cyclone genesis indices that empirically relate tropical cyclone genesis to large-scale variables. We find a shift toward greater (smaller) average potential number of genesis at higher (lower) latitudes over most regions of the Pacific Ocean, which is consistent with a migration of tropical cyclone genesis towards higher latitudes. We then examine the global best track archive and find coherent and significant poleward shifts in mean genesis position over the Pacific Ocean basins.

  18. Some issues and subtleties in numerical simulation of X-ray FEL's

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fawley, William M.

    Part of the overall design effort for x-ray FEL's such as the LCLS and TESLA projects has involved extensive use of particle simulation codes to predict their output performance and underlying sensitivity to various input parameters (e.g. electron beam emittance). This paper discusses some of the numerical issues that must be addressed by simulation codes in this regime. We first give a brief overview of the standard approximations and simulation methods adopted by time-dependent(i.e. polychromatic) codes such as GINGER, GENESIS, and FAST3D, including the effects of temporal discretization and the resultant limited spectral bandpass,and then discuss the accuracies and inaccuraciesmore » of these codes in predicting incoherent spontaneous emission (i.e. the extremely low gain regime).« less

  19. Genesis field operational test : final evaluation report

    DOT National Transportation Integrated Search

    1997-09-01

    This document is the Final Evaluation Report for the Genesis Advanced Traveler Information System (ATIS) Field Operational Test (FOT). Genesis was one of the early projects sponsored by the US Department of Transportation (USDOT) Intelligent Transpor...

  20. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kobayashi, Tsutomu; Yamaguchi, Masahide; Yokoyama, Jun’ichi

    It has been pointed out that the null energy condition can be violated stably in some non-canonical scalar-field theories. This allows us to consider the Galilean Genesis scenario in which the universe starts expanding from Minkowski spacetime and hence is free from the initial singularity. We use this scenario to study the early-time completion of inflation, pushing forward the recent idea of Pirtskhalava et al. We present a generic form of the Lagrangian governing the background and perturbation dynamics in the Genesis phase, the subsequent inflationary phase, and the graceful exit from inflation, as opposed to employing the effective fieldmore » theory approach. Our Lagrangian belongs to a more general class of scalar-tensor theories than the Horndeski theory and Gleyzes-Langlois-Piazza-Vernizzi generalization, but still has the same number of the propagating degrees of freedom, and thus can avoid Ostrogradski instabilities. We investigate the generation and evolution of primordial perturbations in this scenario and show that one can indeed construct a stable model of inflation preceded by (generalized) Galilean Genesis.« less

  1. Electro-mechanical dynamics of spiral waves in a discrete 2D model of human atrial tissue.

    PubMed

    Brocklehurst, Paul; Ni, Haibo; Zhang, Henggui; Ye, Jianqiao

    2017-01-01

    We investigate the effect of mechano-electrical feedback and atrial fibrillation induced electrical remodelling (AFER) of cellular ion channel properties on the dynamics of spiral waves in a discrete 2D model of human atrial tissue. The tissue electro-mechanics are modelled using the discrete element method (DEM). Millions of bonded DEM particles form a network of coupled atrial cells representing 2D cardiac tissue, allowing simulations of the dynamic behaviour of electrical excitation waves and mechanical contraction in the tissue. In the tissue model, each cell is modelled by nine particles, accounting for the features of individual cellular geometry; and discrete inter-cellular spatial arrangement of cells is also considered. The electro-mechanical model of a human atrial single-cell was constructed by strongly coupling the electrophysiological model of Colman et al. to the mechanical myofilament model of Rice et al., with parameters modified based on experimental data. A stretch-activated channel was incorporated into the model to simulate the mechano-electrical feedback. In order to investigate the effect of mechano-electrical feedback on the dynamics of spiral waves, simulations of spiral waves were conducted in both the electromechanical model and the electrical-only model in normal and AFER conditions, to allow direct comparison of the results between the models. Dynamics of spiral waves were characterized by tracing their tip trajectories, stability, excitation frequencies and meandering range of tip trajectories. It was shown that the developed DEM method provides a stable and efficient model of human atrial tissue with considerations of the intrinsically discrete and anisotropic properties of the atrial tissue, which are challenges to handle in traditional continuum mechanics models. This study provides mechanistic insights into the complex behaviours of spiral waves and the genesis of atrial fibrillation by showing an important role of the mechano-electrical feedback in facilitating and promoting atrial fibrillation.

  2. Electro-mechanical dynamics of spiral waves in a discrete 2D model of human atrial tissue

    PubMed Central

    Zhang, Henggui

    2017-01-01

    We investigate the effect of mechano-electrical feedback and atrial fibrillation induced electrical remodelling (AFER) of cellular ion channel properties on the dynamics of spiral waves in a discrete 2D model of human atrial tissue. The tissue electro-mechanics are modelled using the discrete element method (DEM). Millions of bonded DEM particles form a network of coupled atrial cells representing 2D cardiac tissue, allowing simulations of the dynamic behaviour of electrical excitation waves and mechanical contraction in the tissue. In the tissue model, each cell is modelled by nine particles, accounting for the features of individual cellular geometry; and discrete inter-cellular spatial arrangement of cells is also considered. The electro-mechanical model of a human atrial single-cell was constructed by strongly coupling the electrophysiological model of Colman et al. to the mechanical myofilament model of Rice et al., with parameters modified based on experimental data. A stretch-activated channel was incorporated into the model to simulate the mechano-electrical feedback. In order to investigate the effect of mechano-electrical feedback on the dynamics of spiral waves, simulations of spiral waves were conducted in both the electromechanical model and the electrical-only model in normal and AFER conditions, to allow direct comparison of the results between the models. Dynamics of spiral waves were characterized by tracing their tip trajectories, stability, excitation frequencies and meandering range of tip trajectories. It was shown that the developed DEM method provides a stable and efficient model of human atrial tissue with considerations of the intrinsically discrete and anisotropic properties of the atrial tissue, which are challenges to handle in traditional continuum mechanics models. This study provides mechanistic insights into the complex behaviours of spiral waves and the genesis of atrial fibrillation by showing an important role of the mechano-electrical feedback in facilitating and promoting atrial fibrillation. PMID:28510575

  3. Delayed onset of changes in soma action potential genesis in nociceptive A-beta DRG neurons in vivo in a rat model of osteoarthritis

    PubMed Central

    Wu, Qi; Henry, James L

    2009-01-01

    Background Clinical data on osteoarthritis (OA) suggest widespread changes in sensory function that vary during the progression of OA. In previous studies on a surgically-induced animal model of OA we have observed that changes in structure and gene expression follow a variable trajectory over the initial days and weeks. To investigate mechanisms underlying changes in sensory function in this model, the present electrophysiological study compared properties of primary sensory nociceptive neurons at one and two months after model induction with properties in naïve control animals. Pilot data indicated no difference in C- or Aδ-fiber associated neurons and therefore the focus is on Aβ-fiber nociceptive neurons. Results At one month after unilateral derangement of the knee by cutting the anterior cruciate ligament and removing the medial meniscus, the only changes observed in Aβ-fiber dorsal root ganglion (DRG) neurons were in nociceptor-like unresponsive neurons bearing a hump on the repolarization phase; these changes consisted of longer half width, reflecting slowed dynamics of AP genesis, a depolarized Vm and an increased AP amplitude. At two months, changes observed were in Aβ-fiber high threshold mechanoreceptors, which exhibited shorter AP duration at base and half width, shorter rise time and fall time, and faster maximum rising rate/maximum falling rate, reflecting accelerated dynamics of AP genesis. Conclusion These data indicate that Aβ nociceptive neurons undergo significant changes that vary in time and occur later than changes in structure and in nociceptive scores in this surgically induced OA model. Thus, if changes in Aβ-fiber nociceptive neurons in this model reflect a role in OA pain, they may relate to mechanisms underlying pain associated with advanced OA. PMID:19785765

  4. Simulation of blast-induced early-time intracranial wave physics leading to traumatic brain injury.

    PubMed

    Taylor, Paul A; Ford, Corey C

    2009-06-01

    The objective of this modeling and simulation study was to establish the role of stress wave interactions in the genesis of traumatic brain injury (TBI) from exposure to explosive blast. A high resolution (1 mm3 voxels) five material model of the human head was created by segmentation of color cryosections from the Visible Human Female data set. Tissue material properties were assigned from literature values. The model was inserted into the shock physics wave code, CTH, and subjected to a simulated blast wave of 1.3 MPa (13 bars) peak pressure from anterior, posterior, and lateral directions. Three-dimensional plots of maximum pressure, volumetric tension, and deviatoric (shear) stress demonstrated significant differences related to the incident blast geometry. In particular, the calculations revealed focal brain regions of elevated pressure and deviatoric stress within the first 2 ms of blast exposure. Calculated maximum levels of 15 KPa deviatoric, 3.3 MPa pressure, and 0.8 MPa volumetric tension were observed before the onset of significant head accelerations. Over a 2 ms time course, the head model moved only 1 mm in response to the blast loading. Doubling the blast strength changed the resulting intracranial stress magnitudes but not their distribution. We conclude that stress localization, due to early-time wave interactions, may contribute to the development of multifocal axonal injury underlying TBI. We propose that a contribution to traumatic brain injury from blast exposure, and most likely blunt impact, can occur on a time scale shorter than previous model predictions and before the onset of linear or rotational accelerations traditionally associated with the development of TBI.

  5. Investigating Added Value of Regional Climate Modeling in North American Winter Storm Track Simulations

    NASA Astrophysics Data System (ADS)

    Poan, E.; Gachon, P., Sr.; Laprise, R.; Aider, R.; Dueymes, G.

    2017-12-01

    This study describes a framework using possibilities given by regional climate models (RCMs) to gain insight into extratropical cyclone (EC) activity during winter over North America (NA). Recent past climate period (1981 - 2005) is firstly considered using the NCEP regional reanalysis (NARR) as a reference, along with the European global reanalysis ERA-Interim (ERAI) and two CMIP5 Global Climate Models (GCMs) used to drive the Canadian RCM - version 5 (CRCM5) and the corresponding regional-scale simulations. While ERAI and GCM simulations show basic agreement with NARR in terms of climatological EC track patterns, detailed bias analyses show that, on the one hand, ERAI presents statistically significant positive biases in terms of EC genesis and therefore occurrence while their intensity is well captured. On the other hand, GCMs present large negative intensity biases in the overall NA domain and particularly over the eastern coast. In addition, storm occurrence from GCMs over the northwestern topographic regions is highly overestimated. When the CRCM5 is driven by ERAI, no significant skill deterioration arises and, more importantly, all storm characteristics near areas with main relief and over regions with large water masses are significantly improved with respect to ERAI. Conversely, in GCM-driven simulations, the added value from the CRCM5 is less prominent and systematic, except over western areas with high topography and over the Western Atlantic coastlines where the most frequent and intense ECs are located. Finally, time period near the end of the 21st century (2071-2100) is considered to analyze EC characteristic trends and changes relative to the current climate conditions, showing important modifications in storm activity for certain winter months, especially in term of intensity over the eastern coast.

  6. Audio-magnetotelluric (AMT) study to investigate the genesis of Mujil hill

    NASA Astrophysics Data System (ADS)

    Rahmania, Suryanto, Wiwit

    2017-07-01

    Gunung Mujil is an isolated hill located near Pondoworejo village, Kalibawang sub-district, Kulon Progo district, and Special Province of Yogyakarta. The hill is part of the eastern Kulon Progo mountain range extended relatively in the North-South direction. The lithology of the hill consists of andesite breccia and it's similar with the Old Andesite Formation that built the Kulon Progo Mountains. There are at least two hypothesis about the genesis and the formation mechanism of this hill, (1) it was formed by debris mass from Kulon Progo Mountains, and (2) ) it was formed by an intrusion. Our study intended to determine the subsurface resistivity below the hill and to relating those results to with the scenario of the genesis of the Mujil hill. We conducted Audio-magnetotellurics (AMT) measurements along two lines survey crossing the Mujil hill consisting of 20 measurements. Since the measurements are located near the villages, most of the data has a fair to bad quality and only one station yielded an excellent data. A 1D Forward modeling was then applied to find best-fit model of the AMT data. The results shows that the Mujil hill was built by debris mass of the Old Andesite Formation from Kulon Progo mountain which is represented by a lower resistivity value under the Mujil hill.

  7. Structural Evolution of a Warm Frontal Precipitation Band During GCPEx

    NASA Technical Reports Server (NTRS)

    Colle, Brian A.; Naeger, Aaron; Molthan, Andrew; Nesbitt, Stephen

    2015-01-01

    A warm frontal precipitation band developed over a few hours 50-100 km to the north of a surface warm front. The 3-km WRF was able to realistically simulate band development, although the model is somewhat too weak. Band genesis was associated with weak frontogenesis (deformation) in the presence of weak potential and conditional instability feeding into the band region, while it was closer to moist neutral within the band. As the band matured, frontogenesis increased, while the stability gradually increased in the banding region. Cloud top generating cells were prevalent, but not in WRF (too stable). The band decayed as the stability increased upstream and the frontogenesis (deformation) with the warm front weakened. The WRF may have been too weak and short-lived with the band because too stable and forcing too weak (some micro issues as well).

  8. Three-Dimensional Atom-Probe Tomography: Advances and Applications

    NASA Astrophysics Data System (ADS)

    Seidman, David N.

    2007-08-01

    This review presents the historical temporal evolution of an atom-probe tomograph (APT) from its genesis (1973) from field-ion microscope images of individual tungsten atoms (1955). The capabilities of modern APTs employing either electrical or laser pulsing are discussed. The results of the application of APTs to specific materials science problems are presented for research performed at Northwestern University on the following problems: (a) the segregation of Mg at α-Al/Al3Sc heterophase interfaces, (b) phase decomposition in ternary Ni-Al-Cr and quaternary Ni-Al-Cr-Re alloys, and (c) 3-D nanoscale composition mapping of an InAs semiconductor nanowire whose growth was catalyzed by gold. These results demonstrate that it is now possible to obtain highly quantitative information from APT that can be compared with modeling, theory, simulations, and/or first-principles calculations.

  9. 75 FR 20037 - Petition for Waiver of Compliance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-16

    ... on the passenger car, meet the test performance criteria for flammability and smoke emission... operating diesel locomotives are the Genesis P42-8 model manufactured by General Electric (GE). These...

  10. Genesis Solar Wind Interstream, Coronal Hole and Coronal Mass Ejection Samples: Update on Availability and Condition

    NASA Technical Reports Server (NTRS)

    Allton, J. H.; Gonzalez, C. P.; Allums, K. K.

    2017-01-01

    Recent refinement of analysis of ACE/SWICS data (Advanced Composition Explorer/Solar Wind Ion Composition Spectrometer) and of onboard data for Genesis Discovery Mission of 3 regimes of solar wind at Earth-Sun L1 make it an appropriate time to update the availability and condition of Genesis samples specifically collected in these three regimes and currently curated at Johnson Space Center. ACE/SWICS spacecraft data indicate that solar wind flow types emanating from the interstream regions, from coronal holes and from coronal mass ejections are elementally and isotopically fractionated in different ways from the solar photosphere, and that correction of solar wind values to photosphere values is non-trivial. Returned Genesis solar wind samples captured very different kinds of information about these three regimes than spacecraft data. Samples were collected from 11/30/2001 to 4/1/2004 on the declining phase of solar cycle 23. Meshik, et al is an example of precision attainable. Earlier high precision laboratory analyses of noble gases collected in the interstream, coronal hole and coronal mass ejection regimes speak to degree of fractionation in solar wind formation and models that laboratory data support. The current availability and condition of samples captured on collector plates during interstream slow solar wind, coronal hole high speed solar wind and coronal mass ejections are de-scribed here for potential users of these samples.

  11. Sensitivity of worst-case strom surge considering influence of climate change

    NASA Astrophysics Data System (ADS)

    Takayabu, Izuru; Hibino, Kenshi; Sasaki, Hidetaka; Shiogama, Hideo; Mori, Nobuhito; Shibutani, Yoko; Takemi, Tetsuya

    2016-04-01

    There are two standpoints when assessing risk caused by climate change. One is how to prevent disaster. For this purpose, we get probabilistic information of meteorological elements, from enough number of ensemble simulations. Another one is to consider disaster mitigation. For this purpose, we have to use very high resolution sophisticated model to represent a worst case event in detail. If we could use enough computer resources to drive many ensemble runs with very high resolution model, we can handle these all themes in one time. However resources are unfortunately limited in most cases, and we have to select the resolution or the number of simulations if we design the experiment. Applying PGWD (Pseudo Global Warming Downscaling) method is one solution to analyze a worst case event in detail. Here we introduce an example to find climate change influence on the worst case storm-surge, by applying PGWD to a super typhoon Haiyan (Takayabu et al, 2015). 1 km grid WRF model could represent both the intensity and structure of a super typhoon. By adopting PGWD method, we can only estimate the influence of climate change on the development process of the Typhoon. Instead, the changes in genesis could not be estimated. Finally, we drove SU-WAT model (which includes shallow water equation model) to get the signal of storm surge height. The result indicates that the height of the storm surge increased up to 20% owing to these 150 years climate change.

  12. Sex differences in cell genesis, hippocampal volume and behavioral outcomes in a rat model of neonatal HI

    PubMed Central

    Waddell, Jaylyn; Hanscom, Marie; Edwards, N. Shalon; McKenna, Mary C.; McCarthy, Margaret M.

    2015-01-01

    Hypoxia ischemia (HI) of the brain in near-term and term infants is a leading cause of infant mortality and lifelong disability but current therapeutic approaches remain limited. Males consistently display greater vulnerability to the deleterious consequences of HI in both humans and animal models. Neurogenesis increases after neonatal HI and offers a potential therapeutic target for recovery. The steroid hormone estradiol has been extensively explored as a neuroprotectant in adult models of stroke but with mixed results. Less consideration has been afforded to this naturally occurring agent in the developing brain, which has unique challenges from the adult. Using a model of term HI in the rat we have explored the impact of this insult on cell genesis in the hippocampus of males and females and the ability of estradiol treatment immediately after insult to restore function. Both short-term (3 days) and long-term (7 days) post-injury were assessed and revealed that only females had markedly increased cell genesis on the short-term but both sexes were increased long-term. A battery of behavioral tests revealed motor impairment in males and compromised episodic memory while both sexes were modestly impaired in spatial memory. Juvenile social play was also depressed in both sexes after HI. Estradiol therapy improved behavioral performance in both sexes but did not reverse a deficit in hippocampal volume ipsilateral to the insult. Thus the effects of estradiol do not appear to be via cell death or proliferation but rather involve other components of neural functioning. PMID:26376217

  13. Sex differences in cell genesis, hippocampal volume and behavioral outcomes in a rat model of neonatal HI.

    PubMed

    Waddell, Jaylyn; Hanscom, Marie; Shalon Edwards, N; McKenna, Mary C; McCarthy, Margaret M

    2016-01-01

    Hypoxia-ischemia (HI) of the brain in near-term and term infants is a leading cause of infant mortality and lifelong disability but current therapeutic approaches remain limited. Males consistently display greater vulnerability to the deleterious consequences of HI in both humans and animal models. Neurogenesis increases after neonatal HI and offers a potential therapeutic target for recovery. The steroid hormone estradiol has been extensively explored as a neuroprotectant in adult models of stroke but with mixed results. Less consideration has been afforded to this naturally occurring agent in the developing brain, which has unique challenges from the adult. Using a model of term HI in the rat we have explored the impact of this insult on cell genesis in the hippocampus of males and females and the ability of estradiol treatment immediately after insult to restore function. Both short-term (3 days) and long-term (7 days) post-injury were assessed and revealed that only females had markedly increased cell genesis on the short-term but both sexes were increased long-term. A battery of behavioral tests revealed motor impairment in males and compromised episodic memory while both sexes were modestly impaired in spatial memory. Juvenile social play was also depressed in both sexes after HI. Estradiol therapy improved behavioral performance in both sexes but did not reverse a deficit in hippocampal volume ipsilateral to the insult. Thus the effects of estradiol do not appear to be via cell death or proliferation but rather involve other components of neural functioning. Published by Elsevier Inc.

  14. Art, Education, and Community: Arts Genesis, Inc.

    ERIC Educational Resources Information Center

    Kestler, Carol S.

    Arts Genesis, Inc. (AGI) forms partnerships with diverse communities to assist them in finding fulfillment through the arts by meeting their own self-defined needs; uses arts experiences to encourage discovery, creativity, and diversity; and continually strives for excellence in the arts and education. Arts Genesis grew out of "Project…

  15. ORE's GENeric Evaluation SYStem: GENESYS 1988-89.

    ERIC Educational Resources Information Center

    Baenen, Nancy; And Others

    GENESYS--GENeric Evaluation SYStem--is a method of streamlining data collection and evaluation through the use of computer technology. GENESYS has allowed the Office of Research and Evaluation (ORE) of the Austin (Texas) Independent School District to evaluate a multitude of contrasting programs with limited resources. By standardizing methods and…

  16. Concentrating Solar Power Projects - Genesis Solar Energy Project |

    Science.gov Websites

    Concentrating Solar Power | NREL Genesis Solar Energy Project This page provides information on the Genesis Solar Energy Project, a concentrating solar power (CSP) project, with data organized by background, participants, and power plant configuration. The Project includes two 125-MW units incorporating

  17. Contributions of tropical waves to tropical cyclone genesis over the western North Pacific

    NASA Astrophysics Data System (ADS)

    Wu, Liang; Takahashi, Masaaki

    2018-06-01

    The present study investigates the relationship between the tropical waves and the tropical cyclone (TC) genesis over the western North Pacific (WNP) for the period 1979-2011. Five wave types are considered in this study. It is shown that the TC genesis is strongly related to enhanced low-level vorticity and convection of tropical waves and significant difference are detected in the TC modulation by dynamic and thermodynamic components of the waves. More TCs tend to form in regions of waves with overlapping cyclonic vorticity and active convection. About 83.2% of TCs form within active phase of tropical waves, mainly in a single wave and two coexisting waves. Each wave type-related genesis accounts for about 30% of all TC geneses except for the Kelvin waves that account for only 25.2% of TC geneses. The number of each wave type-related TC genesis consistently varies seasonally with peak in the TC season (July-November), which is attributed to a combined effect of active wave probability and intensity change. The interannual variation in the TC genesis is well reproduced by the tropical wave-related TC genesis, especially in the region east of 150°E. An eastward extension of the enhanced monsoon trough coincides with increased tropical wave activity by accelerated wave-mean flow interaction.

  18. Seamless Modeling for Research & Predictability of Severe Tropical Storms from Weather-to-Climate Timescales

    NASA Astrophysics Data System (ADS)

    Ramaswamy, V.; Chen, J. H.; Delworth, T. L.; Knutson, T. R.; Lin, S. J.; Murakami, H.; Vecchi, G. A.

    2017-12-01

    Damages from catastrophic tropical storms such as the 2017 destructive hurricanes compel an acceleration of scientific advancements to understand the genesis, underlying mechanisms, frequency, track, intensity, and landfall of these storms. The advances are crucial to provide improved early information for planners and responders. We discuss the development and utilization of a global modeling capability based on a novel atmospheric dynamical core ("Finite-Volume Cubed Sphere or FV3") which captures the realism of the recent tropical storms and is a part of the NOAA Next-Generation Global Prediction System. This capability is also part of an emerging seamless modeling system at NOAA/ Geophysical Fluid Dynamics Laboratory for simulating the frequency of storms on seasonal and longer timescales with high fidelity e.g., Atlantic hurricane frequency over the past decades. In addition, the same modeling system has also been employed to evaluate the nature of projected storms on the multi-decadal scales under the influence of anthropogenic factors such as greenhouse gases and aerosols. The seamless modeling system thus facilitates research into and the predictability of severe tropical storms across diverse timescales of practical interest to several societal sectors.

  19. Marijuana Use among Students and Peers.

    ERIC Educational Resources Information Center

    Griffin, Brenda S.; Griffin, Charles T.

    1978-01-01

    A casual path model based on Sutherland's theory was developed and applied to student marijuana use as a specific delinquent act. Two types of differential association were suggested to explain the genesis of marijuana use for the individual. The data tended to lend support to the causal path model. (Author/LPG)

  20. Effect of Sulfate Aerosol Geoengineering on Tropical cyclones

    NASA Astrophysics Data System (ADS)

    Wang, Q.; Moore, J.; Ji, D.

    2017-12-01

    Variation in tropical cyclone (TC) number and intensity is driven in part by changes in the thermodynamics that can be defined by ocean and atmospheric variables. Genesis Potential Index (GPI) and ventilation index (VI) are combinations of potential intensity, vertical wind shear, relative humidity, midlevel entropy deficit, and absolute vorticity that quantify thermodynamic forcing of TC activity under changed climates, and can be calculated from climate model output. Here we use five CMIP5 models running the RCP45 experiment the Geoengineering Model Intercomparison Project (GeoMIP) stratospheric aerosol injection G4 experiment to calculate the two indices over the 2020 to 2069 period. Globally, GPI under G4 is lower than under RCP45, though both have a slight increasing trend. Spatial patterns in the relative effectiveness of geoengineering show reductions in TC in all models in the North Atlantic basin, and northern Indian Ocean in all except NorESM1-M. In the North Pacific, most models also show relative reductions under G4. VI generally coincide with the GPI patterns. Most models project Potential intensity and Relative Humidity to be the dominant variable to affect genesis potential. Changes in vertical wind shear and vorticity are small with scatter across different models and ocean basins. We find that tropopause temperature maybe as important as sea surface temperature in effecting TC genesis. Thus stratospheric aerosol geoengineering impacts on potential intensity and hence TC intensity are reasonably consistent, but probably underestimated by statistical forecasts of Tropical North Atlantic hurricane activity driven by sea surface temperatures alone. However the impacts of geoengineering on other ocean basins are more difficult to assess, and require more complete understanding of their driving parameters under present day climates. Furthermore, the possible effects of stratospheric injection on chemical reactions in the stratosphere, such as ozone, are not well rendered in the models used so far.

  1. Assortative sociality, limited dispersal, infectious disease and the genesis of the global pattern of religion diversity

    PubMed Central

    Fincher, Corey L; Thornhill, Randy

    2008-01-01

    Why are religions far more numerous in the tropics compared with the temperate areas? We propose, as an answer, that more religions have emerged and are maintained in the tropics because, through localized coevolutionary races with hosts, infectious diseases select for three anticontagion behaviours: in-group assortative sociality; out-group avoidance; and limited dispersal. These behaviours, in turn, create intergroup boundaries that effectively fractionate, isolate and diversify an original culture leading to the genesis of two or more groups from one. Religion is one aspect of a group's culture that undergoes this process. If this argument is correct then, across the globe, religion diversity should correlate positively with infectious disease diversity, reflecting an evolutionary history of antagonistic coevolution between parasites and hosts and subsequent religion genesis. We present evidence that supports this model: for a global sample of traditional societies, societal range size is reduced in areas with more pathogens compared with areas with few pathogens, and in contemporary countries religion diversity is positively related to two measures of parasite stress. PMID:18664438

  2. Systematic design and three-dimensional simulation of X-ray FEL oscillator for Shanghai Coherent Light Facility

    NASA Astrophysics Data System (ADS)

    Li, Kai; Deng, Haixiao

    2018-07-01

    The Shanghai Coherent Light Facility (SCLF) is a quasi-continuous wave hard X-ray free electron laser facility, which is currently under construction. Due to the high repetition rate and high-quality electron beams, it is straightforward to consider X-ray free electron laser oscillator (XFELO) operation for the SCLF. In this paper, the main processes for XFELO design, and parameter optimization of the undulator, X-ray cavity, and electron beam are described. A three-dimensional X-ray crystal Bragg diffraction code, named BRIGHT, was introduced for the first time, which can be combined with the GENESIS and OPC codes for the numerical simulations of the XFELO. The performance of the XFELO of the SCLF is investigated and optimized by theoretical analysis and numerical simulation.

  3. 78 FR 49507 - Genesis Solar, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-14

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ER13-2112-000] Genesis Solar, LLC; Supplemental Notice That Initial Market- Based Rate Filing Includes Request for Blanket Section 204 Authorization This is a supplemental notice in the above-referenced proceeding of Genesis Solar...

  4. 75 FR 52966 - Notice of Availability of the Final Environmental Impact Statement for the Genesis Solar, LLC...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... Genesis Solar Energy Project and Proposed California Desert Conservation Area Plan Amendment AGENCY... Solar LLC's Genesis Solar Energy Project (GSEP) and by this notice is announcing its availability. DATES... amendment the CDCA Plan to make the area suitable for solar energy development; a reduced acreage...

  5. Plant cutin genesis: unanswered questions.

    PubMed

    Domínguez, Eva; Heredia-Guerrero, José A; Heredia, Antonio

    2015-09-01

    The genesis of cutin, the main lipid polymer present in the biosphere, has remained elusive for many years. Recently, two main approaches have attempted to explain the process of cutin polymerization. One describes the existence of an acyltransferase cutin synthase enzyme that links activated monomers of cutin in the outer cell wall, while the other shows that plant cutin is the final result of an extracellular nonenzymatic self-assembly and polymerizing process of cutin monomers. In this opinion article, we explain both models and suggest that they could be pieces of a more complex biological scenario. We also highlight their different characteristics and current limitations, and suggest a potential synergism of both hypotheses. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Major collapse of the South Pacific Convergence Zone in the future and its consequences on tropical cyclones.

    NASA Astrophysics Data System (ADS)

    Menkes, C.; Dutheil, C.; Bador, M.; Lengaigne, M.; Lefèvre, J.; Jourdain, N.; Jullien, S.; Vialard, J.; Peltier, A.

    2017-12-01

    The South Pacific convergence zone (SPCZ) is poorly represented in global climate models, with trademark biases such as the "double ITCZ" or related cold tongue biases. Such biases decrease our confidence in climate change projections for this region. We first show that WRF atmospheric simulations using a 1°x1° regional configuration capture the SPCZ mean state and interannual variability well over the 1980-2016 period. We then perform climate change experiments by adding the RCP8.5, 2080-2100 CMIP5 multi-model mean boundary anomalies to the present conditions. We find a 4° equatorward shift of the SPCZ west of 170°W, and associated 40% rainfall reduction in the southwestern Pacific. These results strongly contrast with previous studies based on CMIP5 simulations that suggest a much weaker southwestern Pacific drying ( 7%). Regional sensitivity experiments show that this CMIP5 weak response can be tracked to climatological CMIP5 SST biases, which weaken the humidity transport reduction in the south Pacific in the future and result in an underestimated projected drying of the southwest Pacific. Our experiments also point toward a large increase in the future SPCZ variability with increased frequency of zonal SPCZ events. Next we explore the fate of tropical cyclones by downscaling the previous models to 20 km. The seasonal and spatial distribution of TC genesis and occurrence are in good agreement with the observations albeit with weaker than observed annual numbers. Our reference simulation is able to simulate intense category 4 and 5 TCs. In the future climate, we show a drastic decrease in the number of TCs ( 75%), and the disappearance of the most intense (Cat 4-5) cyclones. Additional regional simulations using a completely different set of physical parameterizations yield very similar results for the SPCZ collapse, including the strong decrease of TC numbers ( 63%), underlining the robustness of our results.

  7. Deciphering the Minimal Algorithm for Development and Information-genesis

    NASA Astrophysics Data System (ADS)

    Li, Zhiyuan; Tang, Chao; Li, Hao

    During development, cells with identical genomes acquires different fates in a highly organized manner. In order to decipher the principles underlining development, we used C.elegans as the model organism. Based on a large set of microscopy imaging, we first constructed a ``standard worm'' in silico: from the single zygotic cell to about 500 cell stage, the lineage, position, cell-cell contact and gene expression dynamics are quantified for each cell in order to investigate principles underlining these intensive data. Next, we reverse-engineered the possible gene-gene/cell-cell interaction rules that are capable of running a dynamic model recapitulating the early fate decisions during C.elegans development. we further formulized the C.elegans embryogenesis in the language of information genesis. Analysis towards data and model uncovered the global landscape of development in the cell fate space, suggested possible gene regulatory architectures and cell signaling processes, revealed diversity and robustness as the essential trade-offs in development, and demonstrated general strategies in building multicellular organisms.

  8. GENESIS: GPS Environmental and Earth Science Information System

    NASA Technical Reports Server (NTRS)

    Hajj, George

    1999-01-01

    This presentation reviews the GPS ENvironmental and Earth Science Information System (GENESIS). The objectives of GENESIS are outlined (1) Data Archiving, searching and distribution for science data products derived from Space borne TurboRogue Space Receivers for GPS science and other ground based GPS receivers, (2) Data browsing using integrated visualization tools, (3) Interactive web/java-based data search and retrieval, (4) Data subscription service, (5) Data migration from existing GPS archived data, (6) On-line help and documentation, and (7) participation in the WP-ESIP federation. The presentation reviews the products and services of Genesis, and the technology behind the system.

  9. Organic matter diagenesis as the key to a unifying theory for the genesis of tabular uranium-vanadium deposits in the Morrison Formation, Colorado Plateau

    USGS Publications Warehouse

    Hansley, P.L.; Spirakis, C.S.

    1992-01-01

    Interstitial, epigenetic amorphous organic matter is intimately associated with uranium in the Grants uranium region and is considered essential to genetic models for these deposits. In contrast, uranium minerals are intimately associated with authigenic vanadium chlorite and vanadium oxides in amorphous organic matter-poor ores of the Slick Rock and Henry Mountains mining districts and therefore, in some genetic models amorphous organic matter is not considered crucial to the formation of these deposits. Differences in organic matter content can be explained by recognizing that amorphous organic matter-poor deposits have been subjected to more advanced stages of diagenesis than amorphous organic matter-rich deposits. Evidence that amorphous organic matter was involved in the genesis of organic matter-poor, as well as organic matter-rich, deposits is described. -from Authors

  10. Origin of the pre-tropical storm Debby (2006) African easterly wave-mesoscale convective system

    NASA Astrophysics Data System (ADS)

    Lin, Yuh-Lang; Liu, Liping; Tang, Guoqing; Spinks, James; Jones, Wilson

    2013-05-01

    The origins of the pre-Debby (2006) mesoscale convective system (MCS) and African easterly wave (AEW) and their precursors were traced back to the southwest Arabian Peninsula, Asir Mountains (AS), and Ethiopian Highlands (EH) in the vicinity of the ITCZ using satellite imagery, GFS analysis data and ARW model. The sources of the convective cloud clusters and vorticity perturbations were attributed to the cyclonic convergence of northeasterly Shamal wind and the Somali jet, especially when the Mediterranean High shifted toward east and the Indian Ocean high strengthened and its associated Somali jet penetrated farther to the north. The cyclonic vorticity perturbations were strengthened by the vorticity stretching associated with convective cloud clusters in the genesis region—southwest Arabian Peninsula. A conceptual model was proposed to explain the genesis of convective cloud clusters and cyclonic vorticity perturbations preceding the pre-Debby (2006) AEW-MCS system.

  11. Investigating added value of regional climate modeling in North American winter storm track simulations

    NASA Astrophysics Data System (ADS)

    Poan, E. D.; Gachon, P.; Laprise, R.; Aider, R.; Dueymes, G.

    2018-03-01

    Extratropical Cyclone (EC) characteristics depend on a combination of large-scale factors and regional processes. However, the latter are considered to be poorly represented in global climate models (GCMs), partly because their resolution is too coarse. This paper describes a framework using possibilities given by regional climate models (RCMs) to gain insight into storm activity during winter over North America (NA). Recent past climate period (1981-2005) is considered to assess EC activity over NA using the NCEP regional reanalysis (NARR) as a reference, along with the European reanalysis ERA-Interim (ERAI) and two CMIP5 GCMs used to drive the Canadian Regional Climate Model—version 5 (CRCM5) and the corresponding regional-scale simulations. While ERAI and GCM simulations show basic agreement with NARR in terms of climatological storm track patterns, detailed bias analyses show that, on the one hand, ERAI presents statistically significant positive biases in terms of EC genesis and therefore occurrence while capturing their intensity fairly well. On the other hand, GCMs present large negative intensity biases in the overall NA domain and particularly over NA eastern coast. In addition, storm occurrence over the northwestern topographic regions is highly overestimated. When the CRCM5 is driven by ERAI, no significant skill deterioration arises and, more importantly, all storm characteristics near areas with marked relief and over regions with large water masses are significantly improved with respect to ERAI. Conversely, in GCM-driven simulations, the added value contributed by CRCM5 is less prominent and systematic, except over western NA areas with high topography and over the Western Atlantic coastlines where the most frequent and intense ECs are located. Despite this significant added-value on seasonal-mean characteristics, a caveat is raised on the RCM ability to handle storm temporal `seriality', as a measure of their temporal variability at a given location. In fact, the driving models induce some significant footprints on the RCM skill to reproduce the intra-seasonal pattern of storm activity.

  12. Power Law Patch Scaling and Lack of Characteristic Wavelength Suggest "Scale-Free" Processes Drive Pattern Formation in the Florida Everglades

    NASA Astrophysics Data System (ADS)

    Kaplan, D. A.; Casey, S. T.; Cohen, M. J.; Acharya, S.; Jawitz, J. W.

    2016-12-01

    A century of hydrologic modification has altered the physical and biological drivers of landscape processes in the Everglades (Florida, USA). Restoring the ridge-slough patterned landscape, a dominant feature of the historical system, is a priority, but requires an understanding of pattern genesis and degradation mechanisms. Physical experiments to evaluate alternative pattern formation mechanisms are limited by the long time scales of peat accumulation and loss, necessitating model-based comparisons, where support for a particular mechanism is based on model replication of extant patterning and trajectories of degradation. However, multiple mechanisms yield patch elongation in the direction of historical flow (a central feature of ridge-slough patterning), limiting the utility of that characteristic for discriminating among alternatives. Using data from vegetation maps, we investigated the statistical features of ridge-slough spatial patterning (ridge density, patch perimeter, elongation, patch-size distributions, and spatial periodicity) to establish more rigorous criteria for evaluating model performance and to inform controls on pattern variation across the contemporary system. Two independent analyses (2-D periodograms and patch size distributions) provide strong evidence against regular patterning, with the landscape exhibiting neither a characteristic wavelength nor a characteristic patch size, both of which are expected under conditions that produce regular patterns. Rather, landscape properties suggest robust scale-free patterning, indicating genesis from the coupled effects of local facilitation and a global negative feedback operating uniformly at the landscape-scale. This finding challenges widespread invocation of scale-dependent negative feedbacks for explaining ridge-slough pattern origins. These results help discern among genesis mechanisms and provide an improved statistical description of the landscape that can be used to compare among model outputs, as well as to assess the success of future restoration projects.

  13. A hydrogeologic model of stratiform copper mineralization in the Midcontinent Rift System, Northern Michigan, USA

    USGS Publications Warehouse

    Swenson, J.B.; Person, M.; Raffensperger, Jeff P.; Cannon, W.F.; Woodruff, L.G.; Berndt, M.E.

    2004-01-01

    This paper presents a suite of two-dimensional mathematical models of basin-scale groundwater flow and heat transfer for the middle Proterozoic Midcontinent Rift System. The models were used to assess the hydrodynamic driving mechanisms responsible for main-stage stratiform copper mineralization of the basal Nonesuch Formation during the post-volcanic/pre-compressional phase of basin evolution. Results suggest that compaction of the basal aquifer (Copper Harbor Formation), in response to mechanical loading during deposition of the overlying Freda Sandstone, generated a pulse of marginward-directed, compaction-driven discharge of cupriferous brines from within the basal aquifer. The timing of this pulse is consistent with the radiometric dates for the timing of mineralization. Thinning of the basal aquifer near White Pine, Michigan, enhanced stratiform copper mineralization. Focused upward leakage of copper-laden brines into the lowermost facies of the pyrite-rich Nonesuch Formation resulted in copper sulfide mineralization in response to a change in oxidation state. Economic-grade mineralization within the White Pine ore district is a consequence of intense focusing of compaction-driven discharge, and corresponding amplification of leakage into the basal Nonesuch Formation, where the basal aquifer thins dramatically atop the Porcupine Mountains volcanic structure. Equilibrium geochemical modeling and mass-balance calculations support this conclusion. We also assessed whether topography and density-driven flow systems could have caused ore genesis at White Pine. Topography-driven flow associated with the Ottawan orogeny was discounted because it post-dates main-stage ore genesis and because recent seismic interpretations of basin inversion indicates that basin geometry would not be conductive to ore genesis. Density-driven flow systems did not produce focused discharge in the vicinity of the White Pine ore district.

  14. Modulation of Tropical Cyclone Genesis by Boreal Summer Intraseasonal Oscillation: An Anomalous Dynamic Genesis Potential Index

    NASA Astrophysics Data System (ADS)

    Moon, J.; Wang, B.

    2016-12-01

    The large scale circulation anomalies associated with boreal summer intraseasonal oscillation (BSISO) strongly controls the genesis of tropical cyclone in a global perspective. The present study attempts to reveal factors by which BSISO modulation of tropical cyclone genesis (TCG) using two genesis potential indices (GPI): Dynamic GPI (DGPI) and Emanuel and Nolan's GPI (ENGPI). The ENGPI contains two dynamic (the vertical wind shear and absolute vorticity at 850 hPa) and two thermodynamic factors (relative humidity at 600 hPa and maximum potential intensity), while DPGI replaced the two thermodynamic factors by two additional dynamic factors (500 hPa vertical velocity and meridional shear of zonal winds). The major basins of tropical cyclone genesis during May to October from 1979 to 2014 are divided into North Indian Ocean (NIO), Western North Pacific (WNP), Eastern North Pacific (ENP), and North Atlantic (NAT). The genesis numbers of tropical cyclone at each basin increased distinctively at its maximum active phase of BSISO, showing the significant modulation of ISO on tropical cyclone genesis in the Northern Hemisphere. Analysis of the individual contribution of each factors in GPI reveals that the vertical velocity at 500hPa of DGPI and the relative humidity at 600hPa of ENGPI play the most important role in modulating TCG by BSISO. The SST and maximum potential intensity of ENGPI did not represent important physical processes by which the BSISO circulation anomalies affect TCG. The evolution of eight-phase BSISO with intraseasonal prediction of TCG revealed great improvement by DGPI. The evolution of TCG associated with BSISO by basins, such as NIO, WNP, ENP, and NAT showed good performance in featuring the TCG variability, indicating the possibility of improving subseasonal prediction of TCG by our new DGPI.

  15. Cleaning Genesis Mission Payload for Flight with Ultra-Pure Water and Assembly in ISO Class 4 Environment

    NASA Technical Reports Server (NTRS)

    Allton, Judith H.

    2012-01-01

    Genesis mission to capture and return to Earth solar wind samples had very stringent contamination control requirements in order to distinguish the solar atoms from terrestrial ones. Genesis mission goals were to measure solar composition for most of the periodic table, so great care was taken to avoid particulate contamination. Since the number 1 and 2 science goals were to determine the oxygen and nitrogen isotopic composition, organic contamination was minimized by tightly controlling offgassing. The total amount of solar material captured in two years is about 400 micrograms spread across one sq m. The contamination limit requirement for each of C, N, and O was <1015 atoms/sq cm. For carbon, this is equivalent to 10 ng/cm2. Extreme vigilance was used in pre-paring Genesis collectors and cleaning hardware for flight. Surface contamination on polished silicon wafers, measured in Genesis laboratory is approximately 10 ng/sq cm.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bahrdt, J.; Frentrup, W.; Gaupp, A.

    BESSY plans to build a SASE-FEL facility for the energy range from 20 eV to 1000 eV. The energy range will be covered by three APPLE II type undulators with a magnetic length of about 60 m each. This paper summarizes the basic parameters of the FEL-undulators. The magnetic design will be presented. A modified APPLE II design will be discussed which provides higher fields at the expense of reduced horizontal access. GENESIS simulations give an estimate on the tolerances for the beam wander and for gap errors.

  17. Spontaneous and amplified radiation at the initial stage of a SASE FEL.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huang, Z.; Kim, K.-J.

    At the initial stage of a self-amplified spontaneous emission (SASE) free-electron laser (FEL), spontaneous undulator radiation in certain experimental configurations can dominate the amplified signal over an extended undulator distance. In this paper they study both the spontaneous and the amplified radiation in the framework of the paraxial wave equation and determine the transition from the dominance of spontaneous emission to exponential amplification. They compare theoretical expectations with SASE simulation codes GINGER and GENESIS.

  18. The Genesis solar xenon composition and its relationship to planetary xenon signatures

    NASA Astrophysics Data System (ADS)

    Crowther, S. A.; Gilmour, J. D.

    2013-12-01

    The fluence and isotopic composition of solar wind xenon have been determined from silicon collector targets flown on the NASA Genesis mission. A protocol was developed to extract gas quantitatively from samples of ∼9-25 mm2, and xenon measured using the RELAX mass spectrometer. The fluence of implanted solar wind xenon is 1.202(87) × 106 atoms 132Xe cm-2, which equates to a flux of 5.14(21) × 106 atoms 132Xe cm-2 year-1 at the L1 point. This value is in good agreement with those reported in other studies. The isotopic composition of the solar wind is consistent with that extracted from the young lunar regolith and other Genesis collector targets. The more precise xenon isotopic data derived from the Genesis mission confirm models of relationships among planetary xenon signatures. The underlying composition of Xe-Q is mass fractionated solar wind; small, varying contributions of Xe-HL and 129Xe from 129I decay are present in reported meteorite analyses. In contrast, an s-process deficit is apparent in Xe-P3, which appears to have been mass fractionated to the same extent as Xe-Q from a precursor composition, suggesting similar trapping mechanisms. Solar wind xenon later evolved by the addition of ∼1% (at 132Xe) of s-process xenon to this precursor. As an alternative model to a single source reservoir for Xe-P3, we propose that trapping of xenon onto carbonaceous carriers has been an ongoing process across galactic history, and that preparation of the residues in which Xe-P3 has been identified preferentially preserves longer lived host phases; a higher proportion of these sample xenon isotopic compositions from earlier in galactic chemical evolution, allowing the s-process deficit to become apparent. The relationships among SW-Xe, Xe-Q and Xe-P3 predict that the 124Xe/132Xe ratio for the solar wind is 0.00481(6).

  19. Solar composition from the Genesis Discovery Mission

    PubMed Central

    Burnett, D. S.; Team, Genesis Science

    2011-01-01

    Science results from the Genesis Mission illustrate the major advantages of sample return missions. (i) Important results not otherwise obtainable except by analysis in terrestrial laboratories: the isotopic compositions of O, N, and noble gases differ in the Sun from other inner solar system objects. The N isotopic composition is the same as that of Jupiter. Genesis has resolved discrepancies in the noble gas data from solar wind implanted in lunar soils. (ii) The most advanced analytical instruments have been applied to Genesis samples, including some developed specifically for the mission. (iii) The N isotope result has been replicated with four different instruments. PMID:21555545

  20. Decrease of tropical cyclone genesis frequency in the western North Pacific since 1960s

    NASA Astrophysics Data System (ADS)

    Hu, Feng; Li, Tim; Liu, Jia; Bi, Mingyu; Peng, Melinda

    2018-03-01

    Tropical cyclone (TC) genesis frequency in the western North Pacific (WNP) during 1960-2014 shows a step-by-step decrease on interdecadal timescale, in accordance to the phase of the Interdecadal Pacific Oscillation (IPO). The environmental parameters responsible for the interdecadal change of TC genesis frequency were investigated. It was found that vertical wind shear especially the zonal wind shear plays a critical role, while other parameters such as sea surface temperature (SST), vertical velocity, divergence, humidity and maximum potential intensity cannot explain the step-by-step decrease of TC genesis frequency. A further diagnosis shows that the interdecadal change of vertical wind shear is caused by SST and associated rainfall pattern changes across the Indo-Pacific Ocean. A stronger warming in the Indian Ocean/western Pacific from 1960-1976 to 1977-1998 led to enhanced convection over the Maritime Continent and thus strengthened vertical shear over the key TC genesis region in the WNP. A La Nina-like SST pattern change from 1977-1998 to 1999-2014 led to a strengthened Walker circulation in the tropical Pacific, which further enhanced the vertical shear and decreased TC genesis frequency in the WNP.

  1. New Results from the Flare Genesis Experiment

    NASA Astrophysics Data System (ADS)

    Rust, D. M.; Bernasconi, P. N.; Eaton, H. A.; Keller, C.; Murphy, G. A.; Schmieder, B.

    2000-05-01

    From January 10 to 27, 2000, the Flare Genesis solar telescope observed the Sun while suspended from a balloon in the stratosphere above Antarctica. The goal of the mission was to acquire long time series of high-resolution images and vector magnetograms of the solar photosphere and chromosphere. Images were obtained in the magnetically sensitive Ca I line at 6122 Angstroms and at H-alpha (6563 Angstroms). The FGE data were obtained in the context of Max Millennium Observing Campaign #004, the objective of which was to study the ``Genesis of Solar Flares and Active Filaments/Sigmoids." Flare Genesis obtained about 26,000 usable images on the 8 targeted active regions. A preliminary examination reveals a good sequence on an emerging flux region and data on the M1 flare on January 22, as well as a number of sequences on active filaments. We will present the results of our first analysis efforts. Flare Genesis was supported by NASA grants NAG5-4955, NAG5-5139, and NAG5-8331 and by NSF grant OPP-9615073. The Air Force Office of Scientific Research and the Ballistic Missile Defense Organization supported early development of the Flare Genesis Experiment.

  2. The Role of Thermodynamic Processes in the Evolution of Single and Multi-banding within Winter Storms

    NASA Astrophysics Data System (ADS)

    Ganetis, Sara Anne

    Mesoscale precipitation bands within Northeast U.S. (NEUS) winter storms result in heterogeneous spatial and temporal snowfall. Several studies have provided analysis of snowbands focusing on larger, meso-beta scale bands with lengths (L) > 200 km known as single bands. NEUS winter storms can also exhibit multiple bands with meso-beta scale (L < 200 km) and similar spatial orientation and when ≥ 3 occur are termed multi-bands; however, the genesis and evolution of multi-bands is less well understood. Unlike single bands, there is no multi-bands climatological study. In addition, there has been little detailed thermodynamic analysis of snowbands. This dissertation utilizes radar observations, reanalyses, and high-resolution model simulations to explore the thermodynamic evolution of single and multi-bands. Bands are identified within 20 cool season (October-April) NEUS storms. The 110-case dataset was classified using a combination of automated and manual methods into: single band only (SINGLE), multi-bands only (MULTI), both single and multi-bands (BOTH), and non-banded (NONE). Multi-bands occur with the presence of a single band in 55.4% of times used in this study, without the presence of a single band 18.1% of the time, and precipitation exhibits no banded characteristics 23.8% of the time. Most MULTI events occur in the northeast quadrant of a developing cyclone poleward of weak-midlevel forcing along a warm front, whereas multi-bands associated with BOTH events mostly occur in the northwest quadrant of mature cyclones associated with strong mid-level frontogenesis and conditional symmetric instability. The non-banded precipitation associated with NONE events occur in the eastern quadrants of developing and mature cyclones lacking mid-level forcing to concentrate the precipitation into bands. A high-resolution mesoscale model is used to explore the evolution of single and multi-bands based on two case studies, one of a single band and one of multi-bands. The multi-bands form in response to intermittent mid-level frontogenetical forcing in a conditionally unstable environment. The bands within their genesis location southeast of the single band move northwest towards the single band by 700-hPa steering flow. This allows for the formation of new multi-bands within the genesis region, unlike the single band that remains fixed to a 700-hPa frontogenesis maximum. Latent heating within the band is shown to increase the intensity and duration of single and multi-bands through decreased geopotential height below the heating maximum that leads to increased convergence within the band.

  3. Genesis Failure Investigation Report

    NASA Technical Reports Server (NTRS)

    Klein, John

    2004-01-01

    The-Genesis mission to collect solar-wind samples and return them to Earth for detailed analysis proceeded successfully for 3.5 years. During reentry on September 8, 2004, a failure in the entry, descent and landing sequence resulted in a crash landing of the Genesis sample return capsule. This document describes the findings of the avionics sub-team that supported the accident investigation of the JPL Failure Review Board.

  4. Genesis of Twin Tropical Cyclones as Revealed by a Global Mesoscale Model: The Role of Mixed Rossby Gravity Waves

    NASA Technical Reports Server (NTRS)

    Shen, Bo-Wen; Tao, Wei-Kuo; Lin, Yuh-Lang; Laing, Arlene

    2012-01-01

    In this study, it is proposed that twin tropical cyclones (TCs), Kesiny and 01A, in May 2002 formed in association with the scale interactions of three gyres that appeared as a convectively-coupled mixed Rossby gravity (ccMRG) wave during an active phase of the Madden-Julian Oscillation (MJO). This is shown by analyzing observational data and performing simulations using a global mesoscale model. A 10-day control run is initialized at 0000 UTC 1 May 2002 with grid-scale condensation but no cumulus parameterizations. The ccMRG wave was identified as encompassing two developing and one non-developing gyres, the first two of which intensified and evolved into the twin TCs. The control run is able to reproduce the evolution of the ccMRG wave and the formation of the twin TCs about two and five days in advance as well as their subsequent intensity evolution and movement within an 8-10 day period. Five additional 10-day sensitivity experiments with different model configurations are conducted to help understand the interaction of the three gyres. These experiments suggest the improved lead time in the control run may be attributed to the realistic simulation of the ccMRG wave with the following processes: (I) wave deepening associated with wave shortening and/or the intensification of individual gyres, (2) poleward movement of gyres that may be associated with bOlll1dary layer processes, (3) realistic simulation of moist processes at regional scales in association with each of the gyres, and (4) the vertical phasing of low- and mid-level cyclonic circulations associated with a specific gyre.

  5. Electrophysiological and Structural Remodeling in Heart Failure Modulate Arrhythmogenesis. 2D Simulation Study

    PubMed Central

    Gomez, Juan F.; Cardona, Karen; Martinez, Laura; Saiz, Javier; Trenor, Beatriz

    2014-01-01

    Background Heart failure is operationally defined as the inability of the heart to maintain blood flow to meet the needs of the body and it is the final common pathway of various cardiac pathologies. Electrophysiological remodeling, intercellular uncoupling and a pro-fibrotic response have been identified as major arrhythmogenic factors in heart failure. Objective In this study we investigate vulnerability to reentry under heart failure conditions by incorporating established electrophysiological and anatomical remodeling using computer simulations. Methods The electrical activity of human transmural ventricular tissue (5 cm×5 cm) was simulated using the human ventricular action potential model Grandi et al. under control and heart failure conditions. The MacCannell et al. model was used to model fibroblast electrical activity, and their electrotonic interactions with myocytes. Selected degrees of diffuse fibrosis and variations in intercellular coupling were considered and the vulnerable window (VW) for reentry was evaluated following cross-field stimulation. Results No reentry was observed in normal conditions or in the presence of HF ionic remodeling. However, defined amount of fibrosis and/or cellular uncoupling were sufficient to elicit reentrant activity. Under conditions where reentry was generated, HF electrophysiological remodeling did not alter the width of the VW. However, intermediate fibrosis and cellular uncoupling significantly widened the VW. In addition, biphasic behavior was observed, as very high fibrotic content or very low tissue conductivity hampered the development of reentry. Detailed phase analysis of reentry dynamics revealed an increase of phase singularities with progressive fibrotic components. Conclusion Structural remodeling is a key factor in the genesis of vulnerability to reentry. A range of intermediate levels of fibrosis and intercellular uncoupling can combine to favor reentrant activity. PMID:25054335

  6. Genesis of Twin Tropical Cyclones as Revealed by a Global Mesoscale Model: The Role of Mixed Rossby Gravity Waves

    NASA Technical Reports Server (NTRS)

    Shen, Bo-Wen; Tao, Wei-Kuo; Lin, Yuh-Lang; Laing, Arlene

    2012-01-01

    In this study, it is proposed that twin tropical cyclones (TCs), Kesiny and 01A, in May 2002 formed in association with the scale interactions of three gyres that appeared as a convectively coupled mixed Rossby gravity (ccMRG) wave during an active phase of the Madden-Julian Oscillation (MJO). This is shown by analyzing observational data, including NCEP reanalysis data and METEOSAT 7 IR satellite imagery, and performing numerical simulations using a global mesoscale model. A 10-day control run is initialized at 0000 UTC 1 May 2002 with grid-scale condensation but no sub-grid cumulus parameterizations. The ccMRG wave was identified as encompassing two developing and one non-developing gyres, the first two of which intensified and evolved into the twin TCs. The control run is able to reproduce the evolution of the ccMRG wave and thus the formation of the twin TCs about two and five days in advance as well as their subsequent intensity evolution and movement within an 8-10 day period. Five additional 10-day sensitivity experiments with different model configurations are conducted to help understand the interaction of the three gyres, leading to the formation of the TCs. These experiments suggest the improved lead time in the control run may be attributed to the realistic simulation of the ccMRG wave with the following processes: (1) wave deepening (intensification) associated with a reduction in wavelength and/or the intensification of individual gyres, (2) poleward movement of gyres that may be associated with boundary layer processes, (3) realistic simulation of moist processes at regional scales in association with each of the gyres, and (4) the vertical phasing of low- and mid-level cyclonic circulations associated with a specific gyre.

  7. Using Enabling Technologies to Facilitate the Comparison of Satellite Observations with the Model Forecasts for Hurricane Study

    NASA Astrophysics Data System (ADS)

    Li, P.; Knosp, B.; Hristova-Veleva, S. M.; Niamsuwan, N.; Johnson, M. P.; Shen, T. P. J.; Tanelli, S.; Turk, J.; Vu, Q. A.

    2014-12-01

    Due to their complexity and volume, the satellite data are underutilized in today's hurricane research and operations. To better utilize these data, we developed the JPL Tropical Cyclone Information System (TCIS) - an Interactive Data Portal providing fusion between Near-Real-Time satellite observations and model forecasts to facilitate model evaluation and improvement. We have collected satellite observations and model forecasts in the Atlantic Basin and the East Pacific for the hurricane seasons since 2010 and supported the NASA Airborne Campaigns for Hurricane Study such as the Genesis and Rapid Intensification Processes (GRIP) in 2010 and the Hurricane and Severe Storm Sentinel (HS3) from 2012 to 2014. To enable the direct inter-comparisons of the satellite observations and the model forecasts, the TCIS was integrated with the NASA Earth Observing System Simulator Suite (NEOS3) to produce synthetic observations (e.g. simulated passive microwave brightness temperatures) from a number of operational hurricane forecast models (HWRF and GFS). An automated process was developed to trigger NEOS3 simulations via web services given the location and time of satellite observations, monitor the progress of the NEOS3 simulations, display the synthetic observation and ingest them into the TCIS database when they are done. In addition, three analysis tools, the joint PDF analysis of the brightness temperatures, ARCHER for finding the storm-center and the storm organization and the Wave Number Analysis tool for storm asymmetry and morphology analysis were integrated into TCIS to provide statistical and structural analysis on both observed and synthetic data. Interactive tools were built in the TCIS visualization system to allow the spatial and temporal selections of the datasets, the invocation of the tools with user specified parameters, and the display and the delivery of the results. In this presentation, we will describe the key enabling technologies behind the design of the TCIS interactive data portal and analysis tools, including the spatial database technology for the representation and query of the level 2 satellite data, the automatic process flow using web services, the interactive user interface using the Google Earth API, and a common and expandable Python wrapper to invoke the analysis tools.

  8. Simulations of Hurricane Nadine (2012) during HS3 Using the NASA Unified WRF with Aerosol-Cloud Microphysics-Radiation Coupling

    NASA Astrophysics Data System (ADS)

    Shi, J. J.; Braun, S. A.; Sippel, J. A.; Tao, W. K.; Tao, Z.

    2014-12-01

    The impact of the SAL on the development and intensification of hurricanes has garnered significant attention in recent years. Many past studies have shown that synoptic outbreaks of Saharan dust, which usually occur from late spring to early fall and can extend from western Africa across the Atlantic Ocean into the Caribbean, can have impacts on hurricane genesis and subsequent intensity change. The Hurricane and Severe Storm Sentinel (HS3) mission is a multiyear NASA field campaign with the goal of improving understanding of hurricane formation and intensity change. One of HS3's primary science goals is to obtain measurements to help determine the extent to which the Saharan air layer impacts storm intensification. HS3 uses two of NASA's unmanned Global Hawk aircrafts equipped with three instruments each to measure characteristics of the storm environment and inner core. The Goddard microphysics and longwave/shortwave schemes in the NASA Unified Weather Research and Forecasting (NU-WRF) model have been coupled in real-time with the Goddard Chemistry Aerosol Radiation and Transport (GOCART) model in WRF-Chem to account for the direct (radiation) and indirect (microphysics) impact. NU-WRF with interactive aerosol-cloud-radiation physics is used to generate 30-member ensemble simulations of Nadine (2012) with and without the aerosol interactions. Preliminary conclusions related to the impact of the SAL on the evolution of Nadine from the HS3 observations and model output will be described.

  9. Methods of information geometry in computational system biology (consistency between chemical and biological evolution).

    PubMed

    Astakhov, Vadim

    2009-01-01

    Interest in simulation of large-scale metabolic networks, species development, and genesis of various diseases requires new simulation techniques to accommodate the high complexity of realistic biological networks. Information geometry and topological formalisms are proposed to analyze information processes. We analyze the complexity of large-scale biological networks as well as transition of the system functionality due to modification in the system architecture, system environment, and system components. The dynamic core model is developed. The term dynamic core is used to define a set of causally related network functions. Delocalization of dynamic core model provides a mathematical formalism to analyze migration of specific functions in biosystems which undergo structure transition induced by the environment. The term delocalization is used to describe these processes of migration. We constructed a holographic model with self-poetic dynamic cores which preserves functional properties under those transitions. Topological constraints such as Ricci flow and Pfaff dimension were found for statistical manifolds which represent biological networks. These constraints can provide insight on processes of degeneration and recovery which take place in large-scale networks. We would like to suggest that therapies which are able to effectively implement estimated constraints, will successfully adjust biological systems and recover altered functionality. Also, we mathematically formulate the hypothesis that there is a direct consistency between biological and chemical evolution. Any set of causal relations within a biological network has its dual reimplementation in the chemistry of the system environment.

  10. Transient cerebral hypoperfusion and hypertensive events during atrial fibrillation: a plausible mechanism for cognitive impairment

    NASA Astrophysics Data System (ADS)

    Anselmino, Matteo; Scarsoglio, Stefania; Saglietto, Andrea; Gaita, Fiorenzo; Ridolfi, Luca

    2016-06-01

    Atrial fibrillation (AF) is associated with an increased risk of dementia and cognitive decline, independent of strokes. Several mechanisms have been proposed to explain this association, but altered cerebral blood flow dynamics during AF has been poorly investigated: in particular, it is unknown how AF influences hemodynamic parameters of the distal cerebral circulation, at the arteriolar and capillary level. Two coupled lumped-parameter models (systemic and cerebrovascular circulations, respectively) were here used to simulate sinus rhythm (SR) and AF. For each simulation 5000 cardiac cycles were analyzed and cerebral hemodynamic parameters were calculated. With respect to SR, AF triggered a higher variability of the cerebral hemodynamic variables which increases proceeding towards the distal circulation, reaching the maximum extent at the arteriolar and capillary levels. This variability led to critical cerebral hemodynamic events of excessive pressure or reduced blood flow: 303 hypoperfusions occurred at the arteriolar level, while 387 hypertensive events occurred at the capillary level during AF. By contrast, neither hypoperfusions nor hypertensive events occurred during SR. Thus, the impact of AF per se on cerebral hemodynamics candidates as a relevant mechanism into the genesis of AF-related cognitive impairment/dementia.

  11. Equitable Estoppel: Its Genesis, Development, and Application in Government Contracting

    DTIC Science & Technology

    1988-09-30

    NO. CCESSION NO. ,1. T:ITLE (include Security Classification) (UNCLASSIFIED) Equitable Estoppel : Its Genesis, Development, and Application in...sE.UkRm/ CLASSIFICATION OF THIS PAGE AFIT/CI’ "OVERPRINT" Equitable Estoppel : Its Genesis, Development, and Application in Government CoritractingQ By...John Cibinic,Jr. and Ralph C. Nash,Jr. Professors of Law 90 02 12 031 -Table of Contents 1. The Doctrine of Equitable Estoppel -................... 1

  12. The poleward shift of storm tracks under global warming: A Lagrangian perspective

    NASA Astrophysics Data System (ADS)

    Tamarin, T.; Kaspi, Y.

    2017-10-01

    Comprehensive models of climate change projections have shown that the latitudinal band of extratropical storms will likely shift poleward under global warming. Here we study this poleward shift from a Lagrangian storm perspective, through simulations with an idealized general circulation model. By employing a feature tracking technique to identify the storms, we demonstrate that the poleward motion of individual cyclones increases with increasing global mean temperature. A potential vorticity tendency analysis of the cyclone composites highlights two leading mechanisms responsible for enhanced poleward motion: nonlinear horizontal advection and diabatic heating associated with latent heat release. Our results imply that for a 4 K rise in the global mean surface temperature, the mean poleward displacement of cyclones increases by about 0.85° of latitude, and this occurs in addition to a poleward shift of about 0.6° in their mean genesis latitude. Changes in cyclone tracks may have a significant impact on midlatitude climate, especially in localized storm tracks such as the Atlantic and Pacific storm tracks, which may exhibit a more poleward deflected shape.

  13. Automated Method for Estimating Nutation Time Constant Model Parameters for Spacecraft Spinning on Axis

    NASA Technical Reports Server (NTRS)

    2008-01-01

    Calculating an accurate nutation time constant (NTC), or nutation rate of growth, for a spinning upper stage is important for ensuring mission success. Spacecraft nutation, or wobble, is caused by energy dissipation anywhere in the system. Propellant slosh in the spacecraft fuel tanks is the primary source for this dissipation and, if it is in a state of resonance, the NTC can become short enough to violate mission constraints. The Spinning Slosh Test Rig (SSTR) is a forced-motion spin table where fluid dynamic effects in full-scale fuel tanks can be tested in order to obtain key parameters used to calculate the NTC. We accomplish this by independently varying nutation frequency versus the spin rate and measuring force and torque responses on the tank. This method was used to predict parameters for the Genesis, Contour, and Stereo missions, whose tanks were mounted outboard from the spin axis. These parameters are incorporated into a mathematical model that uses mechanical analogs, such as pendulums and rotors, to simulate the force and torque resonances associated with fluid slosh.

  14. The Response of Atlantic Tropical Cyclones to Suppression of African Easterly Waves

    NASA Astrophysics Data System (ADS)

    Patricola, Christina M.; Saravanan, R.; Chang, Ping

    2018-01-01

    Atlantic tropical cyclone (TC) genesis is strongly linked with African easterly waves (AEWs) on the synoptic time scale. However, the TC-AEW relationship is unclear on interannual to climate time scales, and it is unknown whether AEWs are necessary to maintain climatological TC frequency, that is, whether TCs are limited by AEWs. We investigated the impact of AEW suppression on seasonal Atlantic TC activity using a 10-member ensemble of regional climate model simulations in which AEWs were either prescribed or removed through the lateral boundary condition. The climate model experiments produced no significant change in seasonal Atlantic TC number, indicating that AEWs are not necessary to maintain climatological basin-wide TC frequency even though TCs readily originate from these types of disturbances. This suggests that the specific type of "seedling" disturbance is unimportant for determining basin-wide seasonal Atlantic TC number and that in the absence of AEWs, TCs will generate by other mechanisms. The results imply that changes in the presence of AEWs may not be reliable predictors of seasonal variability and future change in Atlantic TC frequency.

  15. The engram formation and the global oscillations of CA3.

    PubMed

    Ventriglia, Francesco

    2008-12-01

    The investigation on the conditions which cause global population oscillatory activities in neural fields, originated some years ago with reference to a kinetic theory of neural systems, as been further deepened in this paper. In particular, the genesis of sharp waves and of some rhythmic activities, such as theta and gamma rhythms, of the hippocampal CA3 field, behaviorally important for their links to learning and memory, has been analyzed with more details. To this aim, the modeling-computational framework previously devised for the study of activities in large neural fields, has been enhanced in such a way that a greater number of biological features, extended dendritic trees-in particular, could be taken into account. By using that methodology, a two-dimensional model of the entire CA3 field has been described and its activity, as it results from the several external inputs impinging on it, has been simulated. As a consequence of these investigations, some hypotheses have been elaborated about the possible function of global oscillatory activities of neural populations of Hippocampus in the engram formation.

  16. A small-scale dynamo in feedback-dominated galaxies - III. Cosmological simulations

    NASA Astrophysics Data System (ADS)

    Rieder, Michael; Teyssier, Romain

    2017-12-01

    Magnetic fields are widely observed in the Universe in virtually all astrophysical objects, from individual stars to entire galaxies, even in the intergalactic medium, but their specific genesis has long been debated. Due to the development of more realistic models of galaxy formation, viable scenarios are emerging to explain cosmic magnetism, thanks to both deeper observations and more efficient and accurate computer simulations. We present here a new cosmological high-resolution zoom-in magnetohydrodynamic (MHD) simulation, using the adaptive mesh refinement technique, of a dwarf galaxy with an initially weak and uniform magnetic seed field that is amplified by a small-scale dynamo (SSD) driven by supernova-induced turbulence. As first structures form from the gravitational collapse of small density fluctuations, the frozen-in magnetic field separates from the cosmic expansion and grows through compression. In a second step, star formation sets in and establishes a strong galactic fountain, self-regulated by supernova explosions. Inside the galaxy, the interstellar medium becomes highly turbulent, dominated by strong supersonic shocks, as demonstrated by the spectral analysis of the gas kinetic energy. In this turbulent environment, the magnetic field is quickly amplified via a SSD process and is finally carried out into the circumgalactic medium by a galactic wind. This realistic cosmological simulation explains how initially weak magnetic seed fields can be amplified quickly in early, feedback-dominated galaxies, and predicts, as a consequence of the SSD process, that high-redshift magnetic fields are likely to be dominated by their small-scale components.

  17. Variability of North Atlantic Hurricane Frequency in a Large Ensemble of High-Resolution Climate Simulations

    NASA Astrophysics Data System (ADS)

    Mei, W.; Kamae, Y.; Xie, S. P.

    2017-12-01

    Forced and internal variability of North Atlantic hurricane frequency during 1951-2010 is studied using a large ensemble of climate simulations by a 60-km atmospheric general circulation model that is forced by observed sea surface temperatures (SSTs). The simulations well capture the interannual-to-decadal variability of hurricane frequency in best track data, and further suggest a possible underestimate of hurricane counts in the current best track data prior to 1966 when satellite measurements were unavailable. A genesis potential index (GPI) averaged over the Main Development Region (MDR) accounts for more than 80% of the forced variations in hurricane frequency, with potential intensity and vertical wind shear being the dominant factors. In line with previous studies, the difference between MDR SST and tropical mean SST is a simple but useful predictor; a one-degree increase in this SST difference produces 7.1±1.4 more hurricanes. The hurricane frequency also exhibits internal variability that is comparable in magnitude to the interannual variability. The 100-member ensemble allows us to address the following important questions: (1) Are the observations equivalent to one realization of such a large ensemble? (2) How many ensemble members are needed to reproduce the variability in observations and in the forced component of the simulations? The sources of the internal variability in hurricane frequency will be identified and discussed. The results provide an explanation for the relatively week correlation ( 0.6) between MDR GPI and hurricane frequency on interannual timescales in observations.

  18. Tropical cyclogenesis in warm climates simulated by a cloud-system resolving model

    NASA Astrophysics Data System (ADS)

    Fedorov, Alexey V.; Muir, Les; Boos, William R.; Studholme, Joshua

    2018-03-01

    Here we investigate tropical cyclogenesis in warm climates, focusing on the effect of reduced equator-to-pole temperature gradient relevant to past equable climates and, potentially, to future climate change. Using a cloud-system resolving model that explicitly represents moist convection, we conduct idealized experiments on a zonally periodic equatorial β-plane stretching from nearly pole-to-pole and covering roughly one-fifth of Earth's circumference. To improve the representation of tropical cyclogenesis and mean climate at a horizontal resolution that would otherwise be too coarse for a cloud-system resolving model (15 km), we use the hypohydrostatic rescaling of the equations of motion, also called reduced acceleration in the vertical. The simulations simultaneously represent the Hadley circulation and the intertropical convergence zone, baroclinic waves in mid-latitudes, and a realistic distribution of tropical cyclones (TCs), all without use of a convective parameterization. Using this model, we study the dependence of TCs on the meridional sea surface temperature gradient. When this gradient is significantly reduced, we find a substantial increase in the number of TCs, including a several-fold increase in the strongest storms of Saffir-Simpson categories 4 and 5. This increase occurs as the mid-latitudes become a new active region of TC formation and growth. When the climate warms we also see convergence between the physical properties and genesis locations of tropical and warm-core extra-tropical cyclones. While end-members of these types of storms remain very distinct, a large distribution of cyclones forming in the subtropics and mid-latitudes share properties of the two.

  19. Numerical simulation of tornadoes' meteorological conditions over Greece: A case study of tornadic activity over NW Peloponnese on March 25, 2009

    NASA Astrophysics Data System (ADS)

    Matsangouras, Ioannis T.; Nastos, Panagiotis T.; Pytharoulis, Ioannis

    2014-05-01

    Recent research revealed that NW Peloponnese, Greece is an area that favours pre-frontal tornadic incidence. This study presents the results of the synoptic analysis of the meteorological conditions during a tornado event over NW Peloponnese on March 25, 2009. Further, the role of topography in tornado genesis is examined. The tornado was formed approximately at 10:30 UTC, south-west of Vardas village, crossed the Nea Manolada and faded away at Lappas village, causing several damage. The length of its track was approximately 9-10 km and this tornado was characterized as F2 (Fujita scale) or T4-T5 in TORRO intensity scale. Synoptic analysis was based on ECMWF datasets, as well as on daily composite mean and anomaly of the geopotential heights at the middle and lower troposphere from NCEP/NCAR reanalysis. In addition, numerous datasets derived from weather observations and remote sensing were used in order to interpret better the examined extreme event. Finally, a numerical simulation was performed using the non-hydrostatic Weather Research and Forecasting model (WRF), initialized with ECMWF gridded analyses, with telescoping nested grids that allow the representation of atmospheric circulations ranging from the synoptic scale down to the meso-scale. In the numerical simulations the topography of the inner grid was modified by: a) 0% (actual topography) and b) -100% (without topography).

  20. Early warning of freshwater salinization due to upward brine displacement by species transport simulations combined with a hydrochemical genesis model

    NASA Astrophysics Data System (ADS)

    Langer, Maria; Kühn, Michael

    2016-04-01

    Shallow groundwater resources could be possibly affected by intruding brines, which are displaced along hydraulically conductive faults as result of subsurface activities like CO2 injection. To avoid salinization of potable freshwater aquifers an early detection of intruding saline water is necessary, especially in regions where an initial geogenic salinization already exists. Our study is based on work of Tillner et al. [1] and Langer et al. [2] who investigated the influence of permeable fault systems on brine displacement for the prospective storage site Beeskow-Birkholz in the Northeast German Basin. With a 3D regional scale model considering the deep groundwater system, they demonstrated that the existence of hydraulically conductive faults is not necessarily an exclusion criterion for potential injection sites, because salinization of shallower aquifers strongly depends on the effective damage zone volume, the initial salinity distribution and overlying reservoirs [2], while permeability of fault zones does not influence salinization of shallower aquifers significantly [1]. Here we extracted a 2D cross section regarding the upper 220 m of the study area mainly represented by shallow freshwater aquifers, but also considering an initial geogenic salinization [3]. We took flow rates of the intruding brines from the previous studies [2] and implemented species transport simulations with the program code SHEMAT [4]. Results are investigated and interpreted with the hydrochemical genesis model GEBAH [5] which has been already applied as early warning of saltwater intrusions into freshwater aquifers and surface water [6]. GEBAH allows a categorization of groundwater by the ion ratios of the dissolved components and offers a first indicative determination for an existence and the intensity of saline water intrusion in shallow groundwater aquifer, independent of the concentration of the solution. With our model we investigated the migration of saline water through a fault or an erosional channel which both allows an exchange between the shallow freshwater and the deeper saline water complex. The salinization potential of a drinking water well in vicinity to the brine source was determined for different scenarios. [1] Tillner E., Kempka T., Nakaten B., Kühn M. (2013) Brine migration through fault zones: 3D numerical simulations for a prospective CO2 storage site in Northeast Germany. International Journal of Greenhouse Gas Control 19, 689-703. doi: 10.1016/ j.ijggc.2013.03.012 [2] Langer M., Tillner E., Kempka T., Kühn M. (2015) Effective damage zone volume of fault zones and initial salinity distribution determine intensity of shallow aquifer salinization in geological underground utilization. Hydrology and Earth System Sciences Discussion, 12, 5703-5748. doi: 10.5194/hessd-12-5703-2015 [3] Hotzan, G., and Voss, T. (2013): Complex hydrogeochemic-genetic mapping for evaluation of the endangerment of pleistocene and tertiary aquifers by saline waters in the region Storkow-Frankfurt (Oder)-Eisenhüttenstadt. Brandenburgische Geowissenschaftliche Beiträge, 20 (1/2), 62-82. (in German) [4] Clauser C. (2003) SHEMAT and Processing SHEMAT - Numerical simulation of reactive flow in hot aquifers, Springer Publishers, Heidelberg [5] Rechlin, B., Hoffknecht, A., Scholz, H., Helms, A. (2010): Genetic evaluation of analyses from the hydrosphere. Software GEBAH Vers. 1.1 LBGR/GCI, Cottbus, Königs Wusterhausen (in German) [6] Rechlin, B. (2008): A method for a concentration free early detection of saltwater intrusions into freshwater aquifers and surface water. Brandenburgische Geowissenschaftliche Beiträge, 15 (1/2), 57-68. (in German)

  1. Mouse Genome Database: From sequence to phenotypes and disease models

    PubMed Central

    Richardson, Joel E.; Kadin, James A.; Smith, Cynthia L.; Blake, Judith A.; Bult, Carol J.

    2015-01-01

    Summary The Mouse Genome Database (MGD, www.informatics.jax.org) is the international scientific database for genetic, genomic, and biological data on the laboratory mouse to support the research requirements of the biomedical community. To accomplish this goal, MGD provides broad data coverage, serves as the authoritative standard for mouse nomenclature for genes, mutants, and strains, and curates and integrates many types of data from literature and electronic sources. Among the key data sets MGD supports are: the complete catalog of mouse genes and genome features, comparative homology data for mouse and vertebrate genes, the authoritative set of Gene Ontology (GO) annotations for mouse gene functions, a comprehensive catalog of mouse mutations and their phenotypes, and a curated compendium of mouse models of human diseases. Here, we describe the data acquisition process, specifics about MGD's key data areas, methods to access and query MGD data, and outreach and user help facilities. genesis 53:458–473, 2015. © 2015 The Authors. Genesis Published by Wiley Periodicals, Inc. PMID:26150326

  2. Mixed clusters from the coexpansion of C2F6 and n2 in a pulsed, supersonic expansion cluster ion source and beam deflection time-of-flight mass spectrometer: A first application

    NASA Astrophysics Data System (ADS)

    Thompson, Steven D.

    The following topics are discussed: (1) cluster ion genesis; (2) cluster ion detection; (3) Ion source; (4) pulse valve; (5) e-gun; (6) Ion optics; (7) a first order model; and (8) a modified Bakker's model.

  3. Designing Spatial Visualisation Tasks for Middle School Students with a 3D Modelling Software: An Instrumental Approach

    ERIC Educational Resources Information Center

    Turgut, Melih; Uygan, Candas

    2015-01-01

    In this work, certain task designs to enhance middle school students' spatial visualisation ability, in the context of an instrumental approach, have been developed. 3D modelling software, SketchUp®, was used. In the design process, software tools were focused on and, thereafter, the aim was to interpret the instrumental genesis and spatial…

  4. Sample Return Missions Where Contamination Issues are Critical: Genesis Mission Approach

    NASA Technical Reports Server (NTRS)

    Allton, Judith H.; Stansbery E. K.

    2011-01-01

    The Genesis Mission, sought the challenging analytical goals of accurately and precisely measuring the elemental and isotopic composition of the Sun to levels useful for planetary science, requiring sensitivities of ppm to ppt in the outer 100 nm of collector materials. Analytical capabilities were further challenged when the hard landing in 2004 broke open the canister containing the super-clean collectors. Genesis illustrates that returned samples allow flexibility and creativity to recover from setbacks.

  5. Interannual Tropical Rainfall Variability in General Circulation Model Simulations Associated with the Atmospheric Model Intercomparison Project.

    NASA Astrophysics Data System (ADS)

    Sperber, K. R.; Palmer, T. N.

    1996-11-01

    The interannual variability of rainfall over the Indian subcontinent, the African Sahel, and the Nordeste region of Brazil have been evaluated in 32 models for the period 1979-88 as part of the Atmospheric Model Intercomparison Project (AMIP). The interannual variations of Nordeste rainfall are the most readily captured, owing to the intimate link with Pacific and Atlantic sea surface temperatures. The precipitation variations over India and the Sahel are less well simulated. Additionally, an Indian monsoon wind shear index was calculated for each model. Evaluation of the interannual variability of a wind shear index over the summer monsoon region indicates that the models exhibit greater fidelity in capturing the large-scale dynamic fluctuations than the regional-scale rainfall variations. A rainfall/SST teleconnection quality control was used to objectively stratify model performance. Skill scores improved for those models that qualitatively simulated the observed rainfall/El Niño- Southern Oscillation SST correlation pattern. This subset of models also had a rainfall climatology that was in better agreement with observations, indicating a link between systematic model error and the ability to simulate interannual variations.A suite of six European Centre for Medium-Range Weather Forecasts (ECMWF) AMIP runs (differing only in their initial conditions) have also been examined. As observed, all-India rainfall was enhanced in 1988 relative to 1987 in each of these realizations. All-India rainfall variability during other years showed little or no predictability, possibly due to internal chaotic dynamics associated with intraseasonal monsoon fluctuations and/or unpredictable land surface process interactions. The interannual variations of Nordeste rainfall were best represented. The State University of New York at Albany/National Center for Atmospheric Research Genesis model was run in five initial condition realizations. In this model, the Nordeste rainfall variability was also best reproduced. However, for all regions the skill was less than that of the ECMWF model.The relationships of the all-India and Sahel rainfall/SST teleconnections with horizontal resolution, convection scheme closure, and numerics have been evaluated. Models with resolution T42 performed more poorly than lower-resolution models. The higher resolution models were predominantly spectral. At low resolution, spectral versus gridpoint numerics performed with nearly equal verisimilitude. At low resolution, moisture convergence closure was slightly more preferable than other convective closure techniques. At high resolution, the models that used moisture convergence closure performed very poorly, suggesting that moisture convergence may be problematic for models with horizontal resolution T42.

  6. Small Particulate Contamination Survey Of Genesis Flight Sample 61423

    NASA Technical Reports Server (NTRS)

    Kuhlman, K. R.; Schmeling, M.; Gonzalez, C. P.; Allums, K. K.; Allton, J. H.; Burnett, D. S.

    2016-01-01

    The Genesis mission collected solar wind and brought it back to Earth in order to provide precise knowledge of solar isotopic and elemental compositions. The ions in the solar wind stop in the collectors at depths on the order of 10 to a few hundred nanometers. This shallow implantation layer is critical for scientific analysis of the composition of the solar wind and must be preserved throughout sample handling, cleaning, processing, distribution, preparation and analysis. We continue to work with the community of scientists analyzing Genesis samples using our unique laboratory facilities -- and, where needed, our unique cleaning techniques -- to significantly enhance the science return from the Genesis mission. This work is motivated by the need to understand the submicron contamination on the collectors in the Genesis payload as recovered from the crash site in the Utah desert, and -- perhaps more importantly -- how to remove it. We continue to evaluate the effectiveness of the wet-chemical "cleaning" steps used by various investigators, to enable them to design improved methods of stripping spacecraft and terrestrial contamination from surfaces while still leaving the solar-wind signal intact.

  7. Influence of the Soil Genesis on Physical and Mechanical Properties

    PubMed Central

    Marschalko, Marian; Yilmaz, Işık; Fojtová, Lucie; Kubečka, Karel; Bouchal, Tomáš; Bednárik, Martin

    2013-01-01

    The paper deals with the influence of soil genesis on the physical-mechanical properties. The presented case study was conducted in the region of the Ostrava Basin where there is a varied genetic composition of the Quaternary geological structure on the underlying Neogeneous sediments which are sediments of analogous granulometry but different genesis. In this study, 7827 soil samples of an eolian, fluvial, glacial, and deluvial origin and their laboratory analyses results were used. The study identified different values in certain cases, mostly in coarser-grained foundation soils, such as sandy loam S4 (MS) and clayey sand F4 (CS). The soils of the fluvial origin manifest different values than other genetic types. Next, based on regression analyses, dependence was proved neither on the deposition depth (depth of samples) nor from the point of view of the individual foundation soil classes or the genetic types. The contribution of the paper is to point at the influence of genesis on the foundation soil properties so that engineering geologists and geotechnicians pay more attention to the genesis during engineering-geological and geotechnical investigations. PMID:23844398

  8. An effort to improve track and intensity prediction of tropical cyclones through vortex initialization in NCUM-global model

    NASA Astrophysics Data System (ADS)

    Singh, Vivek; Routray, A.; Mallick, Swapan; George, John P.; Rajagopal, E. N.

    2016-05-01

    Tropical cyclones (TCs) have strong impact on socio-economic conditions of the countries like India, Bangladesh and Myanmar owing to its awful devastating power. This brings in the need of precise forecasting system to predict the tracks and intensities of TCs accurately well in advance. However, it has been a great challenge for major operational meteorological centers over the years. Genesis of TCs over data sparse warm Tropical Ocean adds more difficulty to this. Weak and misplaced vortices at initial time are one of the prime sources of track and intensity errors in the Numerical Weather Prediction (NWP) models. Many previous studies have reported the forecast skill of track and intensity of TC improved due to the assimilation of satellite data along with vortex initialization (VI). Keeping this in mind, an attempt has been made to investigate the impact of vortex initialization for simulation of TC using UK-Met office global model, operational at NCMRWF (NCUM). This assessment is carried out by taking the case of a extremely severe cyclonic storm "Chapala" that occurred over Arabian Sea (AS) from 28th October to 3rd November 2015. Two numerical experiments viz. Vort-GTS (Assimilation of GTS observations with VI) and Vort-RAD (Same as Vort-GTS with assimilation of satellite data) are carried out. This vortex initialization study in NCUM model is first of its type over North Indian Ocean (NIO). The model simulation of TC is carried out with five different initial conditions through 24 hour cycles for both the experiments. The results indicate that the vortex initialization with assimilation of satellite data has a positive impact on the track and intensity forecast, landfall time and position error of the TCs.

  9. Investigation of Backside Textures for Genesis Solar Wind Silicon Collectors

    NASA Technical Reports Server (NTRS)

    Gonzalez, C. P.; Burkett, P. J.; Rodriguez, M. C.; Allton, J. H.

    2014-01-01

    Genesis solar wind collectors were comprised of a suite of 15 types of ultrapure materials. The single crystal, pure silicon collectors were fabricated by two methods: float zone (FZ) and Czochralski (CZ). Because of slight differences in bulk purity and surface cleanliness among the fabrication processes and the specific vendor, it is desirable to know which variety of silicon and identity of vendor, so that appropriate reference materials can be used. The Czochralski method results in a bulk composition with slightly higher oxygen, for example. The CZ silicon array wafers that were Genesis-flown were purchased from MEMC Electronics. Most of the Genesis-flown FZ silicon was purchased from Unisil and cleaned by MEMC, although a few FZ wafers were acquired from International Wafer Service (IWS).

  10. Hydrologic controls on aperiodic spatial organization of the ridge-slough patterned landscape

    NASA Astrophysics Data System (ADS)

    Casey, Stephen T.; Cohen, Matthew J.; Acharya, Subodh; Kaplan, David A.; Jawitz, James W.

    2016-11-01

    A century of hydrologic modification has altered the physical and biological drivers of landscape processes in the Everglades (Florida, USA). Restoring the ridge-slough patterned landscape, a dominant feature of the historical system, is a priority but requires an understanding of pattern genesis and degradation mechanisms. Physical experiments to evaluate alternative pattern formation mechanisms are limited by the long timescales of peat accumulation and loss, necessitating model-based comparisons, where support for a particular mechanism is based on model replication of extant patterning and trajectories of degradation. However, multiple mechanisms yield a central feature of ridge-slough patterning (patch elongation in the direction of historical flow), limiting the utility of that characteristic for discriminating among alternatives. Using data from vegetation maps, we investigated the statistical features of ridge-slough spatial patterning (ridge density, patch perimeter, elongation, patch size distributions, and spatial periodicity) to establish more rigorous criteria for evaluating model performance and to inform controls on pattern variation across the contemporary system. Mean water depth explained significant variation in ridge density, total perimeter, and length : width ratios, illustrating an important pattern response to existing hydrologic gradients. Two independent analyses (2-D periodograms and patch size distributions) provide strong evidence against regular patterning, with the landscape exhibiting neither a characteristic wavelength nor a characteristic patch size, both of which are expected under conditions that produce regular patterns. Rather, landscape properties suggest robust scale-free patterning, indicating genesis from the coupled effects of local facilitation and a global negative feedback operating uniformly at the landscape scale. Critically, this challenges widespread invocation of scale-dependent negative feedbacks for explaining ridge-slough pattern origins. These results help discern among genesis mechanisms and provide an improved statistical description of the landscape that can be used to compare among model outputs, as well as to assess the success of future restoration projects.

  11. The First Year of Solar-Wind Data From the GENESIS Mission

    NASA Astrophysics Data System (ADS)

    Wiens, R. C.; Barraclough, B. L.; Steinberg, J. T.; Reisenfeld, D. B.; Neugebauer, M.; Burnett, D. S.

    2002-12-01

    The GENESIS mission was launched in August, 2001, and has been in an L1 halo orbit for over a year. The primary purpose of the mission is to collect solar-wind samples that will be returned to Earth in 2004 for high-precision isotopic and elemental analyses. GENESIS uses conventional ion and electron spectrometers to record solar-wind conditions during collection, and to make real-time determinations of the solar-wind regimes to facilitate collection of separate samples of interstream (IS), coronal hole (CH), and coronal mass ejection (CME) flows. Of particular interest is the use of a bi-directional electron (BDE) index to determine the presence of CMEs. And although GENESIS lacks a magnetometer, the field vector, with sign ambiguity, is determined by the electron direction, and matches other spacecraft magnetometer data well. GENESIS in-situ data and on-board regime determinations are available on the web. The data from Fall, 2001 were characterized by numerous CME regimes (comprising 32% of the time in the 4th quarter, based on the on-board algorithm), with little CH flow (only 2%). A strong CH flow was observed every solar rotation from mid-January through late May. June was quiet, nearly all IS flow. The first and second quarters of 2002 were approximately 28% CME flow, with CH flow dropping from 18% to 6%. The discovery of unexpectedly noticeable BDE signals during CH flows at 1 AU (Steinberg et al., 2002) caused us early on to modify our regime selection algorithm to accommodate these. The on-board algorithm intentionally errs on the side of overestimating CME flows in order to keep the CH sample more pure. Comparisons have been made of various compositional parameters determined by Genesis (Barraclough et al., this meeting) and by ACE SWICS (Reisenfeld et al., this meeting) for times corresponding to the Genesis collection periods for each of the three regimes. The Genesis L1 halo orbit is ~0.8 x 0.25 million km radius, somewhat larger than the ~0.3 x 0.2 and ~0.7 x 0.2 million km orbits of ACE and SOHO, respectively, presenting excellent opportunities for multi-spacecraft observations at L1.

  12. Crop Monitoring as a Tool for Modelling the Genesis of Millet Prices in Senegal

    NASA Astrophysics Data System (ADS)

    Jacques, D.; Marinho, E.; Defourny, P.; Waldner, F.; d'Andrimont, R.

    2015-12-01

    Food security in Sahelian countries strongly relies on the ability of markets to transfer staplesfrom surplus to deficit areas. Market failures, leading to the inefficient geographical allocation of food,are expected to emerge from high transportation costs and information asymmetries that are commonin moderately developed countries. As a result, important price differentials are observed betweenproducing and consuming areas which damages both poor producers and food insecure consumers. Itis then vital for policy makers to understand how the prices of agricultural commodities are formed byaccounting for the existing market imperfections in addition to local demand and supply considerations. To address this issue, we have gathered an unique and diversified set of data for Senegal andintegrated it in a spatially explicit model that simulates the functioning of agricultural markets, that isfully consistent with the economic theory. Our departure point is a local demand and supply modelaround each market having its catchment areas determined by the road network. We estimate the localsupply of agricultural commodities from satellite imagery while the demand is assumed to be a functionof the population living in the area. From this point on, profitable transactions between areas with lowprices to areas with high prices are simulated for different levels of per kilometer transportation costand information flows (derived from call details records i.e. mobile phone data). The simulated prices are then comparedwith the actual millet prices. Despite the parsimony of the model that estimates only two parameters, i.e. the per kilometertransportation cost and the information asymmetry resulting from low levels of mobile phone activitybetween markets, it impressively explains more than 80% of the price differentials observed in the 40markets included in the analysis. In one hand these results can be used in the assessment of the socialwelfare impacts of the further development of both road and mobile phone networks in the country. Onthe other hand, the model could be further developed as a precious tool for the prediction of futurestaple prices in the country.

  13. DOUBLED CO2 PRECIPITATION CHANGES FOR THE SUSQUEHANNA BASIN: DOWN-SCALING FROM THE GENESIS GENERAL CIRCULATION MODEL. (R824807)

    EPA Science Inventory

    The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Concl...

  14. Tumour genesis syndrome: severe hypophosphatemia and hypokalemia may be ominous presenting findings in childhood acute myeloid leukaemia.

    PubMed

    Chan, Winnie Ky; Chang, Kai On; Lau, Wing Hung

    2017-08-01

    We report a 16-year-old girl who was diagnosed with acute leukaemia and a marked leucocytosis >200 × 10 9 /L. She presented with marked hypophosphatemia, hypokalemia, acute renal failure and acute respiratory failure. These electrolytes disturbances may indicate rapid tumour genesis. These ominous findings required urgent treatment to halt the crises of rapid leukemic cell proliferation. Mark hypophosphatemia and hypokalemia may be presenting electrolyte abnormalities in a patient with acute leukaemia, and these may be indicators of aggressive tumour genesis. What is known: • Mild electrolyte disturbances are common in oncology patients • Tumour lysis syndrome is well recognized by paediatriaticians What is new: • Life-threatening hypophosphatemia is an uncommon presentation • These electrolytes disorders may indicate an aggressive tumour genesis process even at presentation and require urgent treatment.

  15. Genesis Radiation Environment

    NASA Technical Reports Server (NTRS)

    Minow, Joseph I.; Altstatt, Richard L.; Skipworth, William C.

    2007-01-01

    The Genesis spacecraft launched on 8 August 2001 sampled solar wind environments at L1 from 2001 to 2004. After the Science Capsule door was opened, numerous foils and samples were exposed to the various solar wind environments during periods including slow solar wind from the streamer belts, fast solar wind flows from coronal holes, and coronal mass ejections. The Survey and Examination of Eroded Returned Surfaces (SEERS) program led by NASA's Space Environments and Effects program had initiated access for the space materials community to the remaining Science Capsule hardware after the science samples had been removed for evaluation of materials exposure to the space environment. This presentation will describe the process used to generate a reference radiation Genesis Radiation Environment developed for the SEERS program for use by the materials science community in their analyses of the Genesis hardware.

  16. Prototype of an Integrated Hurricane Information System for Research: Description and Illustration of its Use in Evaluating WRF Model Simulations

    NASA Astrophysics Data System (ADS)

    Hristova-Veleva, S.; Chao, Y.; Vane, D.; Lambrigtsen, B.; Li, P. P.; Knosp, B.; Vu, Q. A.; Su, H.; Dang, V.; Fovell, R.; Tanelli, S.; Garay, M.; Willis, J.; Poulsen, W.; Fishbein, E.; Ao, C. O.; Vazquez, J.; Park, K. J.; Callahan, P.; Marcus, S.; Haddad, Z.; Fetzer, E.; Kahn, R.

    2007-12-01

    In spite of recent improvements in hurricane track forecast accuracy, currently there are still many unanswered questions about the physical processes that determine hurricane genesis, intensity, track and impact on large- scale environment. Furthermore, a significant amount of work remains to be done in validating hurricane forecast models, understanding their sensitivities and improving their parameterizations. None of this can be accomplished without a comprehensive set of multiparameter observations that are relevant to both the large- scale and the storm-scale processes in the atmosphere and in the ocean. To address this need, we have developed a prototype of a comprehensive hurricane information system of high- resolution satellite, airborne and in-situ observations and model outputs pertaining to: i) the thermodynamic and microphysical structure of the storms; ii) the air-sea interaction processes; iii) the larger-scale environment as depicted by the SST, ocean heat content and the aerosol loading of the environment. Our goal was to create a one-stop place to provide the researchers with an extensive set of observed hurricane data, and their graphical representation, together with large-scale and convection-resolving model output, all organized in an easy way to determine when coincident observations from multiple instruments are available. Analysis tools will be developed in the next step. The analysis tools will be used to determine spatial, temporal and multiparameter covariances that are needed to evaluate model performance, provide information for data assimilation and characterize and compare observations from different platforms. We envision that the developed hurricane information system will help in the validation of the hurricane models, in the systematic understanding of their sensitivities and in the improvement of the physical parameterizations employed by the models. Furthermore, it will help in studying the physical processes that affect hurricane development and impact on large-scale environment. This talk will describe the developed prototype of the hurricane information systems. Furthermore, we will use a set of WRF hurricane simulations and compare simulated to observed structures to illustrate how the information system can be used to discriminate between simulations that employ different physical parameterizations. The work described here was performed at the Jet Propulsion Laboratory, California Institute of Technology, under contract with the National Aeronautics ans Space Administration.

  17. 3D virtual human atria: A computational platform for studying clinical atrial fibrillation.

    PubMed

    Aslanidi, Oleg V; Colman, Michael A; Stott, Jonathan; Dobrzynski, Halina; Boyett, Mark R; Holden, Arun V; Zhang, Henggui

    2011-10-01

    Despite a vast amount of experimental and clinical data on the underlying ionic, cellular and tissue substrates, the mechanisms of common atrial arrhythmias (such as atrial fibrillation, AF) arising from the functional interactions at the whole atria level remain unclear. Computational modelling provides a quantitative framework for integrating such multi-scale data and understanding the arrhythmogenic behaviour that emerges from the collective spatio-temporal dynamics in all parts of the heart. In this study, we have developed a multi-scale hierarchy of biophysically detailed computational models for the human atria--the 3D virtual human atria. Primarily, diffusion tensor MRI reconstruction of the tissue geometry and fibre orientation in the human sinoatrial node (SAN) and surrounding atrial muscle was integrated into the 3D model of the whole atria dissected from the Visible Human dataset. The anatomical models were combined with the heterogeneous atrial action potential (AP) models, and used to simulate the AP conduction in the human atria under various conditions: SAN pacemaking and atrial activation in the normal rhythm, break-down of regular AP wave-fronts during rapid atrial pacing, and the genesis of multiple re-entrant wavelets characteristic of AF. Contributions of different properties of the tissue to mechanisms of the normal rhythm and arrhythmogenesis were investigated. Primarily, the simulations showed that tissue heterogeneity caused the break-down of the normal AP wave-fronts at rapid pacing rates, which initiated a pair of re-entrant spiral waves; and tissue anisotropy resulted in a further break-down of the spiral waves into multiple meandering wavelets characteristic of AF. The 3D virtual atria model itself was incorporated into the torso model to simulate the body surface ECG patterns in the normal and arrhythmic conditions. Therefore, a state-of-the-art computational platform has been developed, which can be used for studying multi-scale electrical phenomena during atrial conduction and AF arrhythmogenesis. Results of such simulations can be directly compared with electrophysiological and endocardial mapping data, as well as clinical ECG recordings. The virtual human atria can provide in-depth insights into 3D excitation propagation processes within atrial walls of a whole heart in vivo, which is beyond the current technical capabilities of experimental or clinical set-ups. Copyright © 2011 Elsevier Ltd. All rights reserved.

  18. 3D virtual human atria: A computational platform for studying clinical atrial fibrillation

    PubMed Central

    Aslanidi, Oleg V; Colman, Michael A; Stott, Jonathan; Dobrzynski, Halina; Boyett, Mark R; Holden, Arun V; Zhang, Henggui

    2011-01-01

    Despite a vast amount of experimental and clinical data on the underlying ionic, cellular and tissue substrates, the mechanisms of common atrial arrhythmias (such as atrial fibrillation, AF) arising from the functional interactions at the whole atria level remain unclear. Computational modelling provides a quantitative framework for integrating such multi-scale data and understanding the arrhythmogenic behaviour that emerges from the collective spatio-temporal dynamics in all parts of the heart. In this study, we have developed a multi-scale hierarchy of biophysically detailed computational models for the human atria – 3D virtual human atria. Primarily, diffusion tensor MRI reconstruction of the tissue geometry and fibre orientation in the human sinoatrial node (SAN) and surrounding atrial muscle was integrated into the 3D model of the whole atria dissected from the Visible Human dataset. The anatomical models were combined with the heterogeneous atrial action potential (AP) models, and used to simulate the AP conduction in the human atria under various conditions: SAN pacemaking and atrial activation in the normal rhythm, break-down of regular AP wave-fronts during rapid atrial pacing, and the genesis of multiple re-entrant wavelets characteristic of AF. Contributions of different properties of the tissue to the mechanisms of the normal rhythm and AF arrhythmogenesis are investigated and discussed. The 3D model of the atria itself was incorporated into the torso model to simulate the body surface ECG patterns in the normal and arrhythmic conditions. Therefore, a state-of-the-art computational platform has been developed, which can be used for studying multi-scale electrical phenomena during atrial conduction and arrhythmogenesis. Results of such simulations can be directly compared with experimental electrophysiological and endocardial mapping data, as well as clinical ECG recordings. More importantly, the virtual human atria can provide validated means for directly dissecting 3D excitation propagation processes within the atrial walls from an in vivo whole heart, which are beyond the current technical capabilities of experimental or clinical set-ups. PMID:21762716

  19. Poleward shift and weakening of summer season synoptic activity over India in a warming climate

    NASA Astrophysics Data System (ADS)

    Ravindran, A. M.; Sandeep, S.; Boos, W. R.; TP, S.; Praveen, V.

    2017-12-01

    One of the main components of the Indian summer monsoon is the presence of low intensity cyclonic systems popularly known as Low Pressure Systems (LPS), which contribute more than half of the precipitation received over the fertile Central Indian region. An average of 13 (±2.5) storms develop each boreal summer, with most originating over the Bay of Bengal (BoB) and adjoining land. These systems typically follow a north-west track along the monsoon trough. Despite its significance, the future variability of these storms is not studied, due to the inadequate representation of these systems in current generation climate models. A series of numerical experiments are performed here using the High Resolution Atmospheric Model (HiRAM) with a horizontal grid spacing of 50 km globally to simulate these rain-bearing systems. One set of simulations represents the historical (HIST) period and the other a late 21st century climate scenario based on the strongest Representative Concentration Pathway (RCP8.5). Four ensemble members of these simulations are run, with sea surface temperatures (SSTs) taken from different CMIP5 GCMs selected for their skill in simulating the Indian monsoon. In addition, ten ensemble members of `decadal' experiments are run for both HIST and RCP8.5 to assess model uncertainty, in which the model is forced with annual cycles of decadal mean SSTs. We show that the strength of monsoon LPS activity would decline as much as 50% by the end of the 21st century, under business as usual emission scenario. The overall reduction in the LPS activity is contributed by a 60% decrease in the frequency of storms over the Bay of Bengal, while the weaker systems that form over the land has increased 10% in a warmer climate. Further analysis suggests that a relatively slower rate of warming over the Bay of Bengal compared to the surrounding regions has resulted in an enhanced moist stability over the main genesis region of LPS, which in turn suppressed the growth of these storms in a warmer climate. The change in extreme precipitation may be mentioned as a consequence of ocean-to-land shift in LPS activity.

  20. GENESI-DR - A single access point to Earth Science data

    NASA Astrophysics Data System (ADS)

    Cossu, R.; Goncalves, P.; Pacini, F.

    2009-04-01

    The amount of information being generated about our planet is increasing at an exponential rate, but it must be easily accessible in order to apply it to the global needs relating to the state of the Earth. Currently, information about the state of the Earth, relevant services, analysis results, applications and tools are accessible in a very scattered and uncoordinated way, often through individual initiatives from Earth Observation mission operators, scientific institutes dealing with ground measurements, service companies, data catalogues, etc. A dedicated infrastructure providing transparent access to all this will support Earth Science communities by allowing them to easily and quickly derive objective information and share knowledge based on all environmentally sensitive domains. The use of high-speed networks (GÉANT) and the experimentation of new technologies, like BitTorrent, will also contribute to better services for the Earth Science communities. GENESI-DR (Ground European Network for Earth Science Interoperations - Digital Repositories), an ESA-led, European Commission (EC)-funded two-year project, is taking the lead in providing reliable, easy, long-term access to Earth Science data via the Internet. This project will allow scientists from different Earth Science disciplines located across Europe to locate, access, combine and integrate historical and fresh Earth-related data from space, airborne and in-situ sensors archived in large distributed repositories. GENESI-DR builds a federated collection of heterogeneous digital Earth Science repositories to establish a dedicated infrastructure providing transparent access to all this and allowing Earth Science communities to easily and quickly derive objective information and share knowledge based on all environmentally sensitive domains. The federated digital repositories, seen as services and data providers, will share access to their resources (catalogue functions, data access, processing services etc.) and will adhere to a common set of standards / policies / interfaces. The end-users will be provided with a virtual collection of digital Earth Science data, irrespectively of their location in the various single federated repositories. GENESI-DR objectives have lead to the identification of the basic GENESI-DR infrastructure requirements: • Capability, for Earth Science users, to discover data from different European Earth Science Digital Repositories through the same interface in a transparent and homogeneous way; • Easiness and speed of access to large volumes of coherently maintained distributed data in an effective and timely way; • Capability, for DR owners, to easily make available their data to a significantly increased audience with no need to duplicate them in a different storage system. Data discovery is based on a Central Discovery Service, which allows users and applications to easily query information about data collections and products existing in heterogeneous catalogues, at federated DR sites. This service can be accessed by users via web interface, the GENESI-DR Web Portal, or by external applications via open standardized interfaces exposed by the system. The Central Discovery Service identifies the DRs providing products complying with the user search criteria and returns the corresponding access points to the requester. By taking into consideration different and efficient data transfer technologies such as HTTPS, GridFTP and BitTorrent, the infrastructure provides easiness and speed of access. Conversely, for data publishing GENESI-DR provides several mechanisms to assist DR owners in producing a metadata catalogues. In order to reach its objectives, the GENESI-DR e-Infrastructure will be validated against user needs for accessing and sharing Earth Science data. Initially, four specific applications in the land, atmosphere and marine domains have been selected, including: • Near real time orthorectification for agricultural crops monitoring • Urban area mapping in support of emergency response • Data assimilation in GlobModel, addressing major environmental and health issues in Europe, with a particular focus on air quality • SeaDataNet to aid environmental assessments and to forecast the physical state of the oceans in near real time. Other applications will complement this during the second half of the project. GENESI-DR also aims to develop common approaches to preserve the historical archives and the ability to access the derived user information as both software and hardware transformations occur. Ensuring access to Earth Science data for future generations is of utmost importance because it allows for the continuity of knowledge generation improvement. For instance, scientists accessing today's climate change data in 50 years will be able to better understand and detect trends in global warming and apply this knowledge to ongoing natural phenomena. GENESI-DR will work towards harmonising operations and applying approved standards, policies and interfaces at key Earth Science data repositories. To help with this undertaking, GENESI-DR will establish links with the relevant organisations and programmes such as space agencies, institutional environmental programmes, international Earth Science programmes and standardisation bodies.

  1. Experimental and CFD flow studies in an intracranial aneurysm model with Newtonian and non-Newtonian fluids.

    PubMed

    Frolov, S V; Sindeev, S V; Liepsch, D; Balasso, A

    2016-05-18

    According to the clinical data, flow conditions play a major role in the genesis of intracranial aneurysms. The disorder of the flow structure is the cause of damage of the inner layer of the vessel wall, which leads to the development of cerebral aneurysms. Knowledge of the alteration of the flow field in the aneurysm region is important for treatment. The aim is to study quantitatively the flow structure in an patient-specific aneurysm model of the internal carotid artery using both experimental and computational fluid dynamics (CFD) methods with Newtonian and non-Newtonian fluids. A patient-specific geometry of aneurysm of the internal carotid artery was used. Patient data was segmented and smoothed to obtain geometrical model. An elastic true-to-scale silicone model was created with stereolithography. For initial investigation of the blood flow, the flow was visualized by adding particles into the silicone model. The precise flow velocity measurements were done using 1D Laser Doppler Anemometer with a spatial resolution of 50 μ m and a temporal resolution of 1 ms. The local velocity measurements were done at a distance of 4 mm to each other. A fluid with non-Newtonian properties was used in the experiment. The CFD simulations for unsteady-state problem were done using constructed hexahedral mesh for Newtonian and non-Newtonian fluids. Using 1D laser Doppler Anemometer the minimum velocity magnitude at the end of systole -0.01 m/s was obtained in the aneurysm dome while the maximum velocity 1 m/s was at the center of the outlet segment. On central cross section of the aneurysm the maximum velocity value is only 20% of the average inlet velocity. The average velocity on the cross-section is only 11% of the inlet axial velocity. Using the CFD simulation the wall shear stresses for Newtonian and non-Newtonian fluid at the end of systolic phase (t= 0.25 s) were computed. The wall shear stress varies from 3.52 mPa (minimum value) to 10.21 Pa (maximum value) for the Newtonian fluid. For the non-Newtonian fluid the wall shear stress minimum is 2.94 mPa; the maximum is 9.14 Pa. The lowest value of the wall shear stress for both fluids was obtained at the dome of the aneurysm while the highest wall shear stress was at the beginning of the outlet segment. The vortex in the aneurysm region is unstable during the cardiac cycle. The clockwise rotation of the streamlines at the inlet segment for Newtonian and non-Newtonian fluid is shown. The results of the present study are in agreement with the hemodynamics theory of aneurysm genesis. Low value of wall shear stress is observed at the aneurysm dome which can cause a rupture of an aneurysm.

  2. Pyroclastic Flow Generated Tsunami Waves Detected by CALIPSO Borehole Strainmeters at Soufriere Hills, Montserrat During Massive Dome Collapse: Numerical Simulations and Observations

    NASA Astrophysics Data System (ADS)

    van Boskirk, E. J.; Voight, B.; Watts, P.; Widiwijayanti, C.; Mattioli, G. S.; Elsworth, D.; Hidayat, D.; Linde, A.; Malin, P.; Neuberg, J.; Sacks, S.; Shalev, E.; Sparks, R. J.; Young, S. R.

    2004-12-01

    The July 12-13, 2003 eruption (dome collapse plus explosions) of Soufriere Hills Volcano in Montserrat, WI, is the largest historical lava dome collapse with ˜120 million cubic meters of the dome lost. Pyroclastic flows entered the sea at 18:00 AST 12 July at the Tar River Valley (TRV) and continued until the early hours of 13 July. Low-amplitude tsunamis were reported at Antigua and Guadaloupe soon after the dome collapse. At the time of eruption, four CALIPSO borehole-monitoring stations were in the process of being installed, and three very-broad-band Sacks-Evertson dilatometers were operational and recorded the event at 50 sps. The strongest strain signals were recorded at the Trants site, 5 km north of the TRV entry zone, suggesting tsunami waves >1 m high. Debris strandlines closer to TRV recorded runup heights as much as 8 m. We test the hypothesis that the strain signal is related to tsunami waves generated by successive pyroclastic flows induced during the dome collapse. Tsunami simulation models have been generated using GEOWAVE, which uses simple physics to recreate waves generated by idealized pyroclastic flows entering the sea at TRV. Each simulation run contains surface wave amplitude gauges located in key positions to the three borehole sites. These simulated wave amplitudes and periods are compared quantitatively with the data recorded by the dilatometers and with field observations of wave runup, to elucidate the dynamics of pyroclastic flow tsunami genesis and its propagation in shallow ocean water.

  3. Decontaminating Solar Wind Samples with the Genesis Ultra-Pure Water Megasonic Wafer Spin Cleaner

    NASA Technical Reports Server (NTRS)

    Calaway, Michael J.; Rodriquez, M. C.; Allton, J. H.; Stansbery, E. K.

    2009-01-01

    The Genesis sample return capsule, though broken during the landing impact, contained most of the shattered ultra-pure solar wind collectors comprised of silicon and other semiconductor wafers materials. Post-flight analysis revealed that all wafer fragments were littered with surface particle contamination from spacecraft debris as well as soil from the impact site. This particulate contamination interferes with some analyses of solar wind. In early 2005, the Genesis science team decided to investigate methods for removing the surface particle contamination prior to solar wind analysis.

  4. Evaluation of Surface Runoff Generation Processes Using a Rainfall Simulator: A Small Scale Laboratory Experiment

    NASA Astrophysics Data System (ADS)

    Danáčová, Michaela; Valent, Peter; Výleta, Roman

    2017-12-01

    Nowadays, rainfall simulators are being used by many researchers in field or laboratory experiments. The main objective of most of these experiments is to better understand the underlying runoff generation processes, and to use the results in the process of calibration and validation of hydrological models. Many research groups have assembled their own rainfall simulators, which comply with their understanding of rainfall processes, and the requirements of their experiments. Most often, the existing rainfall simulators differ mainly in the size of the irrigated area, and the way they generate rain drops. They can be characterized by the accuracy, with which they produce a rainfall of a given intensity, the size of the irrigated area, and the rain drop generating mechanism. Rainfall simulation experiments can provide valuable information about the genesis of surface runoff, infiltration of water into soil and rainfall erodibility. Apart from the impact of physical properties of soil, its moisture and compaction on the generation of surface runoff and the amount of eroded particles, some studies also investigate the impact of vegetation cover of the whole area of interest. In this study, the rainfall simulator was used to simulate the impact of the slope gradient of the irrigated area on the amount of generated runoff and sediment yield. In order to eliminate the impact of external factors and to improve the reproducibility of the initial conditions, the experiments were conducted in laboratory conditions. The laboratory experiments were carried out using a commercial rainfall simulator, which was connected to an external peristaltic pump. The pump maintained a constant and adjustable inflow of water, which enabled to overcome the maximum volume of simulated precipitation of 2.3 l, given by the construction of the rainfall simulator, while maintaining constant characteristics of the simulated precipitation. In this study a 12-minute rainfall with a constant intensity of 5 mm/min was used to irrigate a corrupted soil sample. The experiment was undertaken for several different slopes, under the condition of no vegetation cover. The results of the rainfall simulation experiment complied with the expectations of a strong relationship between the slope gradient, and the amount of surface runoff generated. The experiments with higher slope gradients were characterised by larger volumes of surface runoff generated, and by shorter times after which it occurred. The experiments with rainfall simulators in both laboratory and field conditions play an important role in better understanding of runoff generation processes. The results of such small scale experiments could be used to estimate some of the parameters of complex hydrological models, which are used to model rainfall-runoff and erosion processes at catchment scale.

  5. Generalized DSS shell for developing simulation and optimization hydro-economic models of complex water resources systems

    NASA Astrophysics Data System (ADS)

    Pulido-Velazquez, Manuel; Lopez-Nicolas, Antonio; Harou, Julien J.; Andreu, Joaquin

    2013-04-01

    Hydrologic-economic models allow integrated analysis of water supply, demand and infrastructure management at the river basin scale. These models simultaneously analyze engineering, hydrology and economic aspects of water resources management. Two new tools have been designed to develop models within this approach: a simulation tool (SIM_GAMS), for models in which water is allocated each month based on supply priorities to competing uses and system operating rules, and an optimization tool (OPT_GAMS), in which water resources are allocated optimally following economic criteria. The characterization of the water resource network system requires a connectivity matrix representing the topology of the elements, generated using HydroPlatform. HydroPlatform, an open-source software platform for network (node-link) models, allows to store, display and export all information needed to characterize the system. Two generic non-linear models have been programmed in GAMS to use the inputs from HydroPlatform in simulation and optimization models. The simulation model allocates water resources on a monthly basis, according to different targets (demands, storage, environmental flows, hydropower production, etc.), priorities and other system operating rules (such as reservoir operating rules). The optimization model's objective function is designed so that the system meets operational targets (ranked according to priorities) each month while following system operating rules. This function is analogous to the one used in the simulation module of the DSS AQUATOOL. Each element of the system has its own contribution to the objective function through unit cost coefficients that preserve the relative priority rank and the system operating rules. The model incorporates groundwater and stream-aquifer interaction (allowing conjunctive use simulation) with a wide range of modeling options, from lumped and analytical approaches to parameter-distributed models (eigenvalue approach). Such functionality is not typically included in other water DSS. Based on the resulting water resources allocation, the model calculates operating and water scarcity costs caused by supply deficits based on economic demand functions for each demand node. The optimization model allocates the available resource over time based on economic criteria (net benefits from demand curves and cost functions), minimizing the total water scarcity and operating cost of water use. This approach provides solutions that optimize the economic efficiency (as total net benefit) in water resources management over the optimization period. Both models must be used together in water resource planning and management. The optimization model provides an initial insight on economically efficient solutions, from which different operating rules can be further developed and tested using the simulation model. The hydro-economic simulation model allows assessing economic impacts of alternative policies or operating criteria, avoiding the perfect foresight issues associated with the optimization. The tools have been applied to the Jucar river basin (Spain) in order to assess the economic results corresponding to the current modus operandi of the system and compare them with the solution from the optimization that maximizes economic efficiency. Acknowledgments: The study has been partially supported by the European Community 7th Framework Project (GENESIS project, n. 226536) and the Plan Nacional I+D+I 2008-2011 of the Spanish Ministry of Science and Innovation (CGL2009-13238-C02-01 and CGL2009-13238-C02-02).

  6. Subduction Thermal Regime, Slab Dehydration, and Seismicity Distribution Beneath Hikurangi Based on 3-D Simulations

    NASA Astrophysics Data System (ADS)

    Suenaga, Nobuaki; Ji, Yingfeng; Yoshioka, Shoichi; Feng, Deshan

    2018-04-01

    The downdip limit of seismogenic interfaces inferred from the subduction thermal regime by thermal models has been suggested to relate to the faulting instability caused by the brittle failure regime in various plate convergent systems. However, the featured three-dimensional thermal state, especially along the horizontal (trench-parallel) direction of a subducted oceanic plate, remains poorly constrained. To robustly investigate and further map the horizontal (trench-parallel) distribution of the subduction regime and subsequently induced slab dewatering in a descending plate beneath a convergent margin, we construct a regional thermal model that incorporates an up-to-date three-dimensional slab geometry and the MORVEL plate velocity to simulate the plate subduction history in Hikurangi. Our calculations suggest an identified thrust zone featuring remarkable slab dehydration near the Taupo volcanic arc in the North Island distributed in the Kapiti, Manawatu, and Raukumara region. The calculated average subduction-associated slab dehydration of 0.09 to 0.12 wt%/km is greater than the dehydration in other portions of the descending slab and possibly contributes to an along-arc variation in the interplate pore fluid pressure. A large-scale slab dehydration (>0.05 wt%/km) and a high thermal gradient (>4 °C/km) are also identified in the Kapiti, Manawatu, and Raukumara region and are associated with frequent deep slow slip events. An intraslab dehydration that exceeds 0.2 wt%/km beneath Manawatu near the source region of tectonic tremors suggests an unknown relationship in the genesis of slow earthquakes.

  7. Apollo 14 Lunar glass fragment known as Genesis bean

    NASA Technical Reports Server (NTRS)

    1972-01-01

    A tiny green glass fragment taken from an Apollo 14 core tube sampling. Because of its scientific significance and shape, the fragment has been nicknamed the 'Genesis bean'. The main constituents are iron and magnesium.

  8. Cleaning Study of Genesis Sample 60487

    NASA Technical Reports Server (NTRS)

    Kuhlman, Kim R.; Rodriquez, M. C.; Gonzalez, C. P.; Allton, J. H.; Burnett, D. S.

    2013-01-01

    The Genesis mission collected solar wind and brought it back to Earth in order to provide precise knowledge of solar isotopic and elemental compositions. The ions in the solar wind were stopped in the collectors at depths on the order of 10 to a few hundred nanometers. This shallow implantation layer is critical for scientific analysis of the composition of the solar wind and must be preserved throughout sample handling, cleaning, processing, distribution, preparation and analysis. Particles of Genesis wafers, brine from the Utah Testing Range and an organic film have deleterious effects on many of the high-resolution instruments that have been developed to analyze the implanted solar wind. We have conducted a correlative microscopic study of the efficacy of cleaning Genesis samples with megasonically activated ultrapure water and UV/ozone cleaning. Sample 60487, the study sample, is a piece of float-zone silicon from the B/C array approximately 4.995mm x 4.145 mm in size

  9. Relative Bioavailability of Silybin A and Silybin B From 2 Multiconstituent Dietary Supplement Formulations Containing Milk Thistle Extract: A Single-dose Study.

    PubMed

    Li, Wen-Yi; Yu, Guo; Hogan, Renee M; Mohandas, Rajesh; Frye, Reginald F; Gumpricht, Eric; Markowitz, John S

    2018-01-01

    The purpose of this study was to compare the bioavailability between 2 milk thistle-containing dietary supplements, Product B and IsaGenesis, in healthy volunteers. Bioavailability between Product B, originally formulated as a powdered capsule, and IsaGenesis, reformulated as a soft gel, were compared by measuring silybin A and silybin B as surrogate pharmacokinetic markers for differences in absorption and bioavailability. For this randomized, open-label, crossover pharmacokinetic study, 12 healthy volunteers consumed a single-dose serving of each supplement separated by at least a 7-day washout period. Serial blood samples were obtained at 0, 0.5, 1, 1.5, 2, 3, 4, 6, and 8 hours and analyzed via LC-MS/MS. Rapid absorption and elimination of silybin A and silybin B have been observed after oral administration of both Product B and IsaGenesis. However, the absorption rate and extent, as indicated by mean the C max and mean plasma AUC, were significantly higher for the IsaGenesis soft gel formulation. The dose-corrected mean C max was 365% and 450% greater for silybin A and B, respectively, relative to powdered Product B. The time to T max was reached, on average, at least 1 hour earlier with IsaGenesis relative to Product B for both silybin A and silybin B. The IsaGenesis soft gel formulation provided substantially greater absorption and bioavailability of silybin A and silybin B relative to the powdered Product B supplement. ClinicalTrials.gov Identifier: NCT02529605. Copyright © 2018 Elsevier HS Journals, Inc. All rights reserved.

  10. EVALUATION OF THE BIOGENESIS SOIL WASHING TECHNOLOGY

    EPA Science Inventory

    The BioGenesis Enterprises, Inc. (BioGenesis) soil washing technology was demonstrated as part of the US Environmental Protection Agency's (EPA) Superfund Innovative Technology Evaluation (SITE) program in November 1992. The demonstration was conducted over three days at a petrol...

  11. The biotic ligand model approach for addressing effects of exposure water chemistry on aquatic toxicity of metals: Genesis and challenges

    EPA Science Inventory

    A major uncertainty in many aquatic risk assessments for toxic chemicals is the aggregate effect of the physicochemical characteristics of exposure media on toxicity, and how this affects extrapolation of laboratory test results to natural systems. A notable example of this is h...

  12. Case study of a severe windstorm over Slovakia and Hungary on 25 June 2008

    NASA Astrophysics Data System (ADS)

    Simon, André; Kaňák, Ján; Sokol, Alois; Putsay, Mária; Uhrínová, Lucia; Csirmaz, Kálmán; Okon, Ľuboslav; Habrovský, Richard

    2011-06-01

    A system of thunderstorms approached the Slovakia and Hungary in the late evening hours of 25 June 2008, causing extensive damage and peak wind gusts up to 40 m/s. This study examines the macro- and mesosynoptic conditions for the windstorm using soundings, analyses, and forecasts of numerical models (ALADIN, ECMWF). A derecho-like character of the event is discussed. Meteosat Second Generation imagery and convective indices inferred from satellite and model data are used to assess the humidity distribution and the conditional instability of the thunderstorm environment. An intrusion of the environmental dry air into the convective system and intensification of downdrafts is considered to be one of the reasons for the damaging winds observed at some areas. This is supported by the radar imagery showing a sudden drop of radar reflectivity and creation of line echo wave patterns and bow echoes. A numerical simulation provided by the non-hydrostatic MM5 model indicated the development of meso-γ scale vortices embedded in the convective system. The genesis and a possible role of such vortices in creating rear-inflow jets and intensifying the low level winds are investigated with the help of the vorticity equation and several other diagnostic parameters. In addition, the effect of various physical parameterisations on the forecast of the windstorm is evaluated.

  13. GENESI-DR Portal: a scientific gateway to distributed repositories

    NASA Astrophysics Data System (ADS)

    Goncalves, Pedro; Brito, Fabrice; D'Andria, Fabio; Cossu, Roberto; Fusco, Luigi

    2010-05-01

    GENESI-DR (Ground European Network for Earth Science Interoperations - Digital Repositories) is a European Commission (EC)-funded project, kicked-off early 2008 lead by ESA; partners include Space Agencies (DLR, ASI, CNES), both space and no-space data providers such as ENEA (I), Infoterra (UK), K-SAT (N), NILU (N), JRC (EU) and industry as Elsag Datamat (I), CS (F) and TERRADUE (I). GENESI-DR intends to meet the challenge of facilitating "time to science" from different Earth Science disciplines in discovery, access and use (combining, integrating, processing, …) of historical and recent Earth-related data from space, airborne and in-situ sensors, which are archived in large distributed repositories. "Discovering" which data are available on a "geospatial web" is one of the main challenges ES scientists have to face today. Some well- known data sets are referred to in many places, available from many sources. For core information with a common purpose many copies are distributed, e.g., VMap0, Landsat, and SRTM. Other data sets in low or local demand may only be found in a few places and niche communities. Relevant services, results of analysis, applications and tools are accessible in a very scattered and uncoordinated way, often through individual initiatives from Earth Observation mission operators, scientific institutes dealing with ground measurements, service companies or data catalogues. In the discourse of Spatial Data Infrastructures, there are "catalogue services" - directories containing information on where spatial data and services can be found. For metadata "records" describing spatial data and services, there are "registries". The Geospatial industry coins specifications for search interfaces, where it might do better to reach out to other information retrieval and Internet communities. These considerations are the basis for the GENESI-DR scientific portal, which adopts a simple model allowing the geo-spatial classification and discovery of information as a loosely connected federation of nodes. This network had however to be resilient to node failures and able to scale with the growing addition of new information about data and services. The GENESI-DR scientific portal is still evolving as the project deploys the different components amongst the different partners, but the aim is to provide the connection to information, establish rights, access it and in some cases apply algorithms using the computer power available on the infrastructure with simple interfaces. As information is discovered in the network, it can be further exploited, filtered or enhanced according to the user goals. To implement this vision two specialized graphical interfaces were designed on the portal. The first, concentrates on the text-based search of information, while the second is a command and control of submission and order status on a distributed processing environment. The text search uses natural language features that extract the spatial temporal components from the user query. This is then propagated to the nodes by mapping them to OpenSearch extensions, and then returned to the user as an aggregated list of the resources. These can either be access points to dataset series or services that can be further analysed and processed. At this stage, the user is presented with dedicated interfaces that correspond to context of the action that is performing. Be it a bulk data download, data processing or data mining, the different services offer specialized interfaces that are integrated on the portal. In the overall, the GENESI-DR project identifies best practices and supporting context for the use of a minimal abstract model to loosely connect a federation of Digital Repositories. Surpassing the apparent lack of cost effectiveness of the Spatial Data Infrastructures effort in developing "catalogue services" is achieved by trimming the use cases to the most common and relevant. The GENESI-DR scientific portal is, as such, the visible front-end of a dedicated infrastructure providing transparent access to information and allowing Earth Science communities to easily and quickly derive objective information and share knowledge based on all environmentally sensitive domains.

  14. Role of endogenous opioid peptides in the pathogenesis of motion sickness

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yasnetsov, V.V.; Il'ina, S.L.; Karsanova, S.K.

    1986-01-01

    This paper examines the pathogenesis of motion sickness and the role of the various neurochemical systems of the body in the genesis of the condition. It has been shown that the endogenous opioid system participates in the genesis of several pathological processes; this was the motivation for the study. The plasma beta-endorphin level was determined in samples from 19 clinically healthy males. Considering the positive prophylactic and therapeutic effect of naloxone against motion sickness it can be postulated that endogenous opioid peptides participate in the genesis of the vestibulo-autonomic disorders in motion sickness.

  15. Mechanisms of genesis of variant translocation in chronic myeloid leukemia are not correlated with ABL1 or BCR deletion status or response to imatinib therapy.

    PubMed

    Richebourg, Steven; Eclache, Virginie; Perot, Christine; Portnoi, Marie-France; Van den Akker, Jacqueline; Terré, Christine; Maareck, Odile; Soenen, Valérie; Viguié, Franck; Laï, Jean-Luc; Andrieux, Joris; Corm, Sélim; Roche-Lestienne, Catherine

    2008-04-15

    Many published studies have indicated that various mechanisms could be involved in the genesis of variant chronic myelogeneous leukemia (CML) translocations. These are mainly one-step or two-step mechanisms, associated or not with deletions adjacent to the translocation junction on der(9) or der(22) chromosomes (or both). Based on the mechanism of genesis, it has been suggested that the complexity may affect the occurrence of ABL1 and BCR deletions (either or both), or may be associated with the CML disease course, and thus could determine the response to imatinib therapy. Through a retrospective molecular cytogenetic study of 41 CML patients with variant Philadelphia chromosome (Ph), we explored the genesis of these variant rearrangements and analyzed the correlation with deletion status and imatinib efficiency. Our results confirmed that the one-step mechanism is the most frequent, evidenced in 30 of 41 patients (73%); 3 patients demonstrated other more complex multistep events and 8 patients (19.5%) harbored ABL1 or BCR deletions that are not significantly associated with the complexity of translocation genesis. We also found no association between one-step, two-step, or multistep mechanisms and the response to imatinib therapy.

  16. Integrating Thermodynamic Models in Geodynamic Simulations: The Example of the Community Software ASPECT

    NASA Astrophysics Data System (ADS)

    Dannberg, J.; Heister, T.; Grove, R. R.; Gassmoeller, R.; Spiegelman, M. W.; Bangerth, W.

    2017-12-01

    Earth's surface shows many features whose genesis can only be understood through the interplay of geodynamic and thermodynamic models. This is particularly important in the context of melt generation and transport: Mantle convection determines the distribution of temperature and chemical composition, the melting process itself is then controlled by the thermodynamic relations and in turn influences the properties and the transport of melt. Here, we present our extension of the community geodynamics code ASPECT, which solves the equations of coupled magma/mantle dynamics, and allows to integrate different parametrizations of reactions and phase transitions: They may alternatively be implemented as simple analytical expressions, look-up tables, or computed by a thermodynamics software. As ASPECT uses a variety of numerical methods and solvers, this also gives us the opportunity to compare different approaches of modelling the melting process. In particular, we will elaborate on the spatial and temporal resolution that is required to accurately model phase transitions, and show the potential of adaptive mesh refinement when applied to melt generation and transport. We will assess the advantages and disadvantages of iterating between fluid dynamics and chemical reactions derived from thermodynamic models within each time step, or decoupling them, allowing for different time step sizes. Beyond that, we will expand on the functionality required for an interface between computational thermodynamics and fluid dynamics models from the geodynamics side. Finally, using a simple example of melting of a two-phase, two-component system, we compare different time-stepping and solver schemes in terms of accuracy and efficiency, in dependence of the time scales of fluid flow and chemical reactions relative to each other. Our software provides a framework to integrate thermodynamic models in high resolution, 3d simulations of coupled magma/mantle dynamics, and can be used as a tool to study links between physical processes and geochemical signals in the Earth.

  17. Validation and Verification of the Correct Operation of the Thermo Fisher Scientific’s Genesys 10S spectrometer used in ANC122 and NF-ANC122

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Colletti, Lisa Michelle

    2016-02-19

    In December of 2015, the old qualified Prim UV-Vis instrument used in the ANC122 and NFANC122 procedures failed its monthly calibration check. Attempts to get the system to pass by cleaning flow cells, replacing the light bulb and realigning the light path failed to get sustained reproducible results from the system. As it could no longer pass QA/QC requirements the decision to take it out of service was made. To replace the system, a previously purchased Thermo Fisher Scientific UV-VIS spectrometer (model Genesys 10S; Serial #: 2L5R059137) was retrieved from storage. This report shows that the system is performing asmore » required and meeting all QC requirements listed in ANC122 and NF-ANC122« less

  18. Genesis and shape of natural solution cavities within salt deposits

    NASA Astrophysics Data System (ADS)

    Gechter, Daniel; Huggenberger, Peter; Ackerer, Philippe; Waber, H. Niklaus

    2008-11-01

    Since the genesis and shape of natural deep-seated cavities within a salt body are insufficiently understood, the current study tries to shed some light on this topic. To this end, freshwater was pumped slowly through a horizontal borehole in rock salt cores. Owing to fast halite dissolution kinetics, high solubility, and slow inflow rate, halite dissolution took place only in the inflow of the rock salt cylinder. The shape of the created cavities is an approximately symmetrical half cone with a horizontal base facing upward. A conceptual model is presented that is inspired by the experimental results and based on theoretical hydraulic-geochemical considerations, as well as on field observations. It proposes that triangular prism or conically shaped cavities develop within salt under confined conditions, where aggressive water flows upward along a fracture/conduit from an insoluble aquifer into the soluble stratum. Such cavity enlargements may cause land subsidence and structure collapse.

  19. A New Perspective on El Niño Diversity and Its Genesis

    NASA Astrophysics Data System (ADS)

    Chen, D.

    2015-12-01

    El Niño is by far the most energetic and influential interannual fluctuation in the Earth's climate system. Despite the tremendous progress in the theory, observation and prediction of El Niño over the past three decades, there is still considerable debate on the classification of El Niño diversity and on the genesis of such diversity. This uncertainty renders El Niño prediction a continuously challenging task. Here we provide a unified perspective on El Niño diversity as well as its causes, based on a fuzzy clustering analysis and model experiments. Specifically, the interannual variability of the tropical Pacific sea surface temperature can be generally classified into three warm patterns and one cold pattern, which together constitute a canonical El Niño/La Niña cycle and its different flavors. Whereas the genesis of the canonical cycle can be readily explained by classic theories, the asymmetry, irregularity and extremes of El Niño may well result from westerly wind bursts, a type of state-dependent atmospheric perturbation in the equatorial Pacific, which strongly affects El Niño but not La Niña due to its unidirectional nature. This suggests that properly accounting for the interplay between the canonical cycle and westerly wind bursts may improve El Niño prediction.

  20. Ontogenic retinal changes in three ecologically distinct elopomorph fishes (Elopomorpha:Teleostei) correlate with light environment and behavior.

    PubMed

    Taylor, Scott M; Loew, Ellis R; Grace, Michael S

    2015-01-01

    Unlike the mammalian retina, the teleost fish retina undergoes persistent neurogenesis from intrinsic stem cells. In marine teleosts, most cone photoreceptor genesis occurs early in the embryonic and larval stages, and rods are added primarily during and after metamorphosis. This study demonstrates a developmental paradigm in elopomorph fishes in which retinas are rod-dominated in larvae, but undergo periods of later cone genesis. Retinal characteristics were compared at different developmental stages among three ecologically distinct elopomorph fishes-ladyfish (Elops saurus), bonefish (Albula vulpes), and speckled worm eel (Myrophis punctatus). The objectives were to improve our understanding of (1) the developmental strategy in the elopomorph retina, (2) the functional architecture of the retina as it relates to ecology, and (3) how the light environment influences photoreceptor genesis. Photoreceptor morphologies, distributions, and spectral absorption were studied at larval, juvenile, and adult stages. Premetamorphic retinas in all three species are rod-dominated, but the retinas of these species undergo dramatic change over the course of development, resulting in juvenile and adult retinal characteristics that correlate closely with ecology. Adult E. saurus has high rod densities, grouped photoreceptors, a reflective tapetum, and longer-wavelength photopigments, supporting vision in turbid, low-light conditions. Adult A. vulpes has high cone densities, low rod densities, and shorter-wavelength photopigments, supporting diurnal vision in shallow, clear water. M. punctatus loses cones during metamorphosis, develops new cones after settlement, and maintains high rod but low cone densities, supporting primarily nocturnal vision. M. punctatus secondary cone genesis occurs rapidly throughout the retina, suggesting a novel mechanism of vertebrate photoreceptor genesis. Finally, in postsettlement M. punctatus, the continuous presence or absence of visible light modulates rod distribution but does not affect secondary cone genesis, suggesting some degree of developmental plasticity influenced by the light environment.

  1. Global Survey of Precipitation Properties Observed during Tropical Cyclogenesis and Their Differences Compared to Nondeveloping Disturbances

    NASA Astrophysics Data System (ADS)

    Zawislak, J.

    2017-12-01

    This study contributes to a global survey of the precipitation properties of developing and nondeveloping tropical disturbances, with a focus on distinguishing properties of those disturbances that develop into tropical cyclones (TCs) from those that do not develop. Precipitation properties are quantified using a unique accumulation of overpasses of pre-genesis TCs and nondeveloping disturbances from multiple satellite-borne passive microwave imagers. The overpasses are a subset of a broader Tropical Cyclone - Passive Microwave (TC-PMW) dataset that encompasses all stages of the TC life cycle. The TC-PMW consists of 14 years (2003-2016) of overpasses of pre-genesis and nondeveloping disturbances globally (the North Atlantic, East Pacific, Central Pacific, West Pacific, northern Indian Ocean, and Southern Hemisphere oceanic basins). Nondeveloping disturbances are defined as those disturbances that do not exceed an "invest" classification by the operational centers (NHC, CPHC, and JTWC). Overall, this study will offer a detailed analysis of the precipitation properties (i.e., areal coverage of rainfall and deep convection, depth, or intensity, of convection, proximity of precipitation to the center) multiple days before genesis. These analyses offer an opportunity to determine whether the properties of precipitation at, and just prior to, genesis are unique compared to previous days of the pre-genesis stage. By evaluating these properties over the robust sample provided by the TC-PMW dataset, results may lend support to the hypothesis that genesis is more closely tied to the fractional coverage of precipitation near the center rather than to any uniquely "intense" convection. The study will also investigate whether there are significant differences among the basins in the properties of precipitation involved in tropical cyclogenesis.

  2. 33 CFR 147.825 - Chevron Genesis Spar safety zone.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) Description. The Chevron Genesis Spar, Green Canyon 205A (GC205A), is located at position 27°46′46.365″ N, 90... is a safety zone. (b) Regulation. No vessel may enter or remain in this safety zone except the...

  3. The Role of “Vortical” Hot Towers in the Formation of Tropical Cyclone Diana (1984).

    NASA Astrophysics Data System (ADS)

    Hendricks, Eric A.; Montgomery, Michael T.; Davis, Christopher A.

    2004-06-01

    A high-resolution (3-km horizontal grid spacing) near-cloud-resolving numerical simulation of the formation of Hurricane Diana (1984) is used to examine the contribution of deep convective processes to tropical cyclone formation. This study is focused on the 3-km horizontal grid spacing simulation because this simulation was previously found to furnish an accurate forecast of the later stages of the observed storm life cycle. The numerical simulation reveals the presence of vortical hot towers, or cores of deep cumulonimbus convection possessing strong vertical vorticity, that arise from buoyancy-induced stretching of local absolute vertical vorticity in a vorticity-rich prehurricane environment.At near-cloud-resolving scales, these vortical hot towers are the preferred mode of convection. They are demonstrated to be the most important influence to the formation of the tropical storm via a two-stage evolutionary process: (i) preconditioning of the local environment via diabatic production of multiple small-scale lower-tropospheric cyclonic potential vorticity (PV) anomalies, and (ii) multiple mergers and axisymmetrization of these low-level PV anomalies. The local warm-core formation and tangential momentum spinup are shown to be dominated by the organizational process of the diabatically generated PV anomalies; the former process being accomplished by the strong vertical vorticity in the hot tower cores, which effectively traps the latent heat from moist convection. In addition to the organizational process of the PV anomalies, the cyclogenesis is enhanced by the aggregate diabatic heating associated with the vortical hot towers, which produces a net influx of low-level mean angular momentum throughout the genesis.Simpler models are examined to elucidate the underlying dynamics of tropical cyclogenesis in this case study. Using the Sawyer Eliassen balanced vortex model to diagnose the macroscale evolution, the cyclogenesis of Diana is demonstrated to proceed in approximate gradient and hydrostatic balance at many instances, where local radial and vertical accelerations are small. Using a shallow water primitive equation model, a characteristic “moist” (diabatic) vortex merger in the cloud-resolving numerical simulation is captured in a large part by the barotropic model. Since a moist merger results in a stronger vortex and occurs twice as fast as a dry merger, it is inferred (consistent with related work) that a net low-level convergence can accelerate and intensify the merger process in the real atmosphere.Although the findings reported herein are based on a sole case study and thus cannot yet be generalized, it is believed the results are sufficiently interesting to warrant further idealized simulations of this nature.


  4. Documenting and Maintaining Native American Languages for the 21st Century: The Indiana University Model.

    ERIC Educational Resources Information Center

    Parks, Douglas R.; Kushner, Julia; Hooper, Wallace; Flavin, Francis; Yellow Bird, Delilah; Ditmar, Selena

    This document compiles five short papers that describe the history and implementation of the Arikara Language Project and the Nakoda Language Project, the development of computer tools for language documentation, and the creation of curriculum materials for these and other projects. These papers are: "Genesis of the Project" (Douglas R.…

  5. Analyzing the influences of two types of El Niño on tropical cyclone genesis with a modified genesis potential index

    NASA Astrophysics Data System (ADS)

    Yang, Yuxing; Yang, Lei; Wang, Faming

    2017-03-01

    To understand the impacts of large-scale circulation during the evolution of El Niño cycle on tropical cyclones (TC) is important and useful for TC forecast. Based on best-track data from the Joint Typhoon Warning Center and reanalysis data from National Centers for Environmental Prediction for the period 1975-2014, we investigated the influences of two types of El Niño, the eastern Pacific El Niño (EP-El Niño) and central Pacific El Niño (CP-El Niño), on global TC genesis. We also examined how various environmental factors contribute to these influences using a modified genesis potential index (MGPI). The composites reproduced for two types of El Niño, from their developing to decaying phases, were able to qualitatively replicate observed cyclogenesis in several basins except for the Arabian Sea. Certain factors of MGPI with more influence than others in various regions are identified. Over the western North Pacific, five variables were all important in the two El Niño types during developing summer (July-August-September) and fall (October-November-December), and decaying spring (April-May-June) and summer. In the eastern Pacific, vertical shear and relative vorticity are the crucial factors for the two types of El Niño during developing and decaying summers. In the Atlantic, vertical shear, potential intensity and relative humidity are important for the opposite variation of EP- and CP-El Niños during decaying summers. In the Southern Hemisphere, the five variables have varying contributions to TC genesis variation during peak season (January-February-March) for the two types of El Niño. In the Bay of Bengal, relative vorticity, humidity and omega may be responsible for clearly reduced TC genesis during developing fall for the two types and slightly suppressed TC cyclogenesis during EP-El Niño decaying spring. In the Arabian Sea, the EP-El Niño generates a slightly positive anomaly of TC genesis during developing falls and decaying springs, but the MGPI failed to capture this variation.

  6. Phase equilibria modeling in igneous petrology: use of COMAGMAT model for simulating fractionation of ferro-basaltic magmas and the genesis of high-alumina basalt

    NASA Astrophysics Data System (ADS)

    Ariskin, Alexei A.

    1999-05-01

    A new version of COMAGMAT-3.5 model designed for computer simulations of equilibrium and fractional crystallization of basaltic magmas at low to high pressures is presented. The most important modifications of COMAGMAT include an ability to calculate more accurately the crystallization of magnetite and ilmenite, allowing the user to study numerically the effect of oxygen fugacity on basalt magma fractionation trends. Methodological principles of the use of COMAGMAT were discussed based on its thermodynamical and empirical basis, including specific details of the model calibration. Using COMAGMAT-3.5 a set of phase equilibria calculations (called Geochemical Thermometry) has been conducted for six cumulative rocks from the Marginal Border Series of the Skaergaard intrusion. As a result, initial magma temperature (1165±10°C) and trapped melt composition proposed to be parental magma to the Skaergaard intrusion were determined. Computer simulations of perfect fractionation of this composition as well as another proposed parent produced petrochemical trends opposite to those followed from natural observations. This is interpreted as evidence for an initial Skaergaard magma containing a large amount of olivine and plagioclase crystals (about 40-45%), so that the proposed and calculated parents are related through the melt trapped in the crystal-liquid mixture. This promotes the conclusion that the Skaergaard magma fractionation process was intermediate between equilibrium and fractional crystallization. In this case the classic Wager's trend should be considered an exception rather than a rule for the differentiation of ferro-basaltic magmas. A polybaric version of COMAGMAT has been applied for the genetic interpretation of a volcanic suite from the Klyuchevskoi volcano, Kamchatka, Russia. To identify petrological processes responsible for the observed suite ranging from high-magnesia to high-alumina basalts, we used the model to simulate the Klyuchevskoi suite assuming isobaric crystallization of a parental HMB magma at a variety of pressures and a separate set of simulations assuming fractionation during continuous magma ascent from a depth of 60 km. These results indicate that the Klyuchevskoi trend can be produced by ˜40% fractionation of Ol-Aug-Sp±Opx assemblages during ascent of the parental HMB magma over the pressure range 19-7 kbar with the rate of decompression being 0.33 kbar/% crystallized (at 1350-1110°C), with ˜2 wt.% of H 2O in the initial melt and ˜3 wt.% of H 2O in the resultant high-Al basalt.

  7. The effects of SST Gradients on Tropical Convective Systems and Implications for Tropical Cyclogenesis

    NASA Astrophysics Data System (ADS)

    Glazer, R.; Bourassa, M. A.; Hart, R. E.

    2013-12-01

    It has long been known that generally the warmer the sea surface temperature (SST), the more possible tropical cyclone (TC) genesis is, assuming the atmosphere is supportive. The conventional wisdom has been that - apart from what the TC cools through upwelling -- one value of SST represents the state of the ocean surface in the region of the storm's inner circulation. With the advent of the satellite era and fine resolution SST datasets now becoming available, we know that in reality there are gradients of SST across which developing TCs move. The influence of those gradients on tropical convection and TC genesis is largely unknown at this time. Previous studies have shown that SST gradients can significantly impact the overlying ocean surface winds leading to areas of enhanced convergence/divergence and Vorticity (Chelton et al. 2004; O'Neill et al. 2005, 2010). The magnitude of this effect approximately increases as the surface wind increases. Work by Minobe et al. (2008) concluded that a sharp SST Gradient, over the Gulf Stream for instance, could produce enough surface wind convergence to maintain a band of precipitation along the ocean front. An analysis of satellite derived SST data over the Atlantic shows that it is not uncommon for SST gradients of 2 C/200km or more to exist in the immediate environment of a Tropical System. The authors seek to understand whether the conclusions made in previous works can be applied in the case of a developing Tropical System and whether SST Gradients exist in the Tropical Atlantic to a degree that would influence the cyclogenesis process. To address this, the effects of SST gradients on tropical cyclogenesis processes are investigated using model simulations of the Weather Research and Forecasting Model (WRF). WRF is run at cloud permitting scales (2km) for real cases of co-location between a tropical system and an SST gradient exceeding 2 C/200km in the environment of the system. In subsequent runs to this control run, the SSTs are modified to give a smaller or larger SST Gradient with the same atmospheric conditions. All cases are chosen from Atlantic Hurricane Seasons between 2002-2011. The results are then analyzed in the framework of previous studies that have sought to model and understand tropical cyclogenesis using WRF (Nolan 2007; Fang and Zhang 2010).

  8. High-resolution computed tomography of single breast cancer microcalcifications in vivo.

    PubMed

    Inoue, Kazumasa; Liu, Fangbing; Hoppin, Jack; Lunsford, Elaine P; Lackas, Christian; Hesterman, Jacob; Lenkinski, Robert E; Fujii, Hirofumi; Frangioni, John V

    2011-08-01

    Microcalcification is a hallmark of breast cancer and a key diagnostic feature for mammography. We recently described the first robust animal model of breast cancer microcalcification. In this study, we hypothesized that high-resolution computed tomography (CT) could potentially detect the genesis of a single microcalcification in vivo and quantify its growth over time. Using a commercial CT scanner, we systematically optimized acquisition and reconstruction parameters. Two ray-tracing image reconstruction algorithms were tested: a voxel-driven "fast" cone beam algorithm (FCBA) and a detector-driven "exact" cone beam algorithm (ECBA). By optimizing acquisition and reconstruction parameters, we were able to achieve a resolution of 104 μm full width at half-maximum (FWHM). At an optimal detector sampling frequency, the ECBA provided a 28 μm (21%) FWHM improvement in resolution over the FCBA. In vitro, we were able to image a single 300 μm × 100 μm hydroxyapatite crystal. In a syngeneic rat model of breast cancer, we were able to detect the genesis of a single microcalcification in vivo and follow its growth longitudinally over weeks. Taken together, this study provides an in vivo "gold standard" for the development of calcification-specific contrast agents and a model system for studying the mechanism of breast cancer microcalcification.

  9. Simulating the Osceola Mudflow Lahar Event in the Pacific Northwest using a GPU Based 2-Dimensional Hydraulic Model

    NASA Astrophysics Data System (ADS)

    Katz, B. G.; Eppert, S.; Lohmann, D.; Li, S.; Goteti, G.; Kaheil, Y. H.

    2011-12-01

    At 4,400 meters, Mount Rainer has been the point of origin for several major lahar events. The largest event, termed the "Osceola Mudflow," occurred 5,500 years ago and covered an area of approximately 550km2 with a total volume of deposited material from 2 to 4km3. Particularly deadly, large lahars are estimated to have maximum flow velocities in of 100km/h with a density often described as "Flowing Concrete." While rare, these events typically cause total destruction within a lahar inundation zone. It is estimated that approximately 150,000 people live on top of previous deposits left by lahars which can be triggered by anything from earthquakes to glacial and chemical erosion of volcanic bedrock over time to liquefaction caused by extreme rainfall events. A novel methodology utilizing a 2 dimensional hydraulic model has been implemented allowing for high resolution (30m) lahar inundation maps to be generated. The utility of this model above or in addition to other methodologies such as that of Iverson (1998), lies in its portability to other lahar zones as well as its ability to model any total volume specified by the user. The process for generating lahar flood plains requires few inputs including: a Digital Terrain Map of any resolution (DTM), a mask defining the locations for lahar genesis, a raster of friction coefficients, and a time series depicting uniform material accumulation over the genesis mask which is allowed to flow down-slope. Finally, a significant improvement in speed has been made for solving the two dimensional model by utilizing the latest in graphics processing unit (GPU) technology which has resulted in a greater than 200 times speed up in model run time over previous CPU-based methods. The model runs for the Osceola Mudflow compare favorably with USGS derived inundation regions as derived using field measurements and GIS based approaches such as the LAHARZ program suit. Overall gradation of low to high risk match well, however the new method allows lahars to flow over a wider range of terrain effecting 800 to 1,700km2 for 2 to 4km3 of source material, a 300 to 150% increase over the literature estimate of 550km2. To demonstrate the portability of this methodology, total set up time for this region was measured in single days, while total run time for a single simulation was 1.5 days for the 42M grid cells within the Mount Rainier study area. Areas of improvement for this methodology include reducing the total effected area by increasing friction coefficients to account for the thicker material within the lahar, as well as utilizing equations specifically for mudflow, such as Meunier's mud/debris equations, for situations where sediment concentration is sufficiently high. The addition of the above may allow for differentiation between cohesive and non-cohesive lahars to be made which has important implications on the length and width of lahar inundation. Additionally, using DTMs which have been corrected to pre-lahar levels while not useable for estimating future risk, would allow for a higher degree of confidence to be placed on modeled versus estimated accumulation map comparisons.

  10. Pristine Igneous Rocks and the Genesis of Early Planetary Crusts

    NASA Technical Reports Server (NTRS)

    Warren, Paul H.; Lindstrom, David (Technical Monitor)

    2002-01-01

    Our studies are highly interdisciplinary, but are focused on the processes and products of early planetary and asteroidal differentiation, especially the genesis of the ancient lunar crust. The compositional diversity that we explore is the residue of process diversity, which has strong relevance for comparative planetology.

  11. Design and realization of the optical and electron beam alignment system for the HUST-FEL oscillator

    NASA Astrophysics Data System (ADS)

    Fu, Q.; Tan, P.; Liu, K. F.; Qin, B.; Liu, X.

    2018-06-01

    A Free Electron Laser(FEL) oscillator with radiation wavelength at 30-100 μ m is under commissioning at Huazhong University of Science and Technology (HUST). This work presents the schematic design and realization procedures for the optical and beam alignment system in the HUST FEL facility. The optical cavity misalignment effects are analyzed with the code OPC + Genesis 1.3, and the tolerance of misalignment is proposed with the simulation result. Depending on undulator mechanical benchmarks, a laser indicating system has been built up as reference datum. The alignment of both optical axis and beam trajectory were achieved by this alignment system.

  12. Who can resist Foucault?

    PubMed

    Bleakley, Alan; Bligh, John

    2009-08-01

    Michel Foucault's analysis of "the birth of the clinic" describes the genesis of a unified discourse that, in retrospect, has shaped western medicine for two centuries. However, in looking prospectively toward a 21st century medicine, Foucault's analysis is necessary but not sufficient. To better critically address medicine and medical education in the era of simulation, we could draw on frameworks developed by futurists such as Jean Baudrillard. Foucault's analysis does not account for contemporary, complex developments of the clinical gaze as the gaze is distributed across practitioners in increasing use of sophisticated, representational diagnostic imaging. Further, Foucault's antihumanist rhetoric sometimes strays into the antihumane, and this is disturbing for those who support the development of patient-centered medicine. Yet we are increasingly teaching aspects of medicine, such as communication, in simulated learning environments in which complex reality is absent, perhaps inadvertently creating an "inhumanity" in medical education.

  13. Solubility of hot fuel particles from Chernobyl--influencing parameters for individual radiation dose calculations.

    PubMed

    Garger, Evgenii K; Meisenberg, Oliver; Odintsov, Oleksiy; Shynkarenko, Viktor; Tschiersch, Jochen

    2013-10-15

    Nuclear fuel particles of Chernobyl origin are carriers of increased radioactivity (hot particles) and are still present in the atmosphere of the Chernobyl exclusion zone. Workers in the zone may inhale these particles, which makes assessment necessary. The residence time in the lungs and the transfer in the blood of the inhaled radionuclides are crucial for inhalation dose assessment. Therefore, the dissolution of several kinds of nuclear fuel particles from air filters sampled in the Chernobyl exclusion zone was studied. For this purpose filter fragments with hot particles were submersed in simulated lung fluids (SLFs). The activities of the radionuclides (137)Cs, (90)Sr, (239+240)Pu and (241)Am were measured in the SLF and in the residuum of the fragments by radiometric methods after chemical treatment. Soluble fractions as well as dissolution rates of the nuclides were determined. The influence of the genesis of the hot particles, represented by the (137)Cs/(239+240)Pu ratio, on the availability of (137)Cs was demonstrated, whereas the dissolution of (90)Sr, (239+240)Pu and (241)Am proved to be independent of genesis. No difference in the dissolution of (137)Cs and (239+240)Pu was observed for the two applied types of SLF. Increased solubility was found for smaller hot particles. A two-component exponential model was used to describe the dissolution of the nuclides as a function of time. The results were applied for determining individual inhalation dose coefficients for the workers at the Chernobyl construction site. Greater dose coefficients for the respiratory tract and smaller coefficients for the other organs were calculated (compared to ICRP default values). The effective doses were in general lower for the considered radionuclides, for (241)Am even by one order of magnitude. © 2013 Elsevier B.V. All rights reserved.

  14. Sensitivity of Last Glacial Maximum climate to uncertainties in tropical and subtropical ocean temperatures

    USGS Publications Warehouse

    Hostetler, S.; Pisias, N.; Mix, A.

    2006-01-01

    The faunal and floral gradients that underlie the CLIMAP (1981) sea-surface temperature (SST) reconstructions for the Last Glacial Maximum (LGM) reflect ocean temperature gradients and frontal positions. The transfer functions used to reconstruct SSTs from biologic gradients are biased, however, because at the warmest sites they display inherently low sensitivity in translating fauna to SST and they underestimate SST within the euphotic zones where the pycnocline is strong. Here we assemble available data and apply a statistical approach to adjust for hypothetical biases in the faunal-based SST estimates of LGM temperature. The largest bias adjustments are distributed in the tropics (to address low sensitivity) and subtropics (to address underestimation in the euphotic zones). The resulting SSTs are generally in better agreement than CLIMAP with recent geochemical estimates of glacial-interglacial temperature changes. We conducted a series of model experiments using the GENESIS general atmospheric circulation model to assess the sensitivity of the climate system to our bias-adjusted SSTs. Globally, the new SST field results in a modeled LGM surface-air cooling relative to present of 6.4 ??C (1.9 ??C cooler than that of CLIMAP). Relative to the simulation with CLIMAP SSTs, modeled precipitation over the oceans is reduced by 0.4 mm d-1 (an anomaly -0.4 versus 0.0 mm d-1 for CLIMAP) and increased over land (an anomaly -0.2 versus -0.5 mm d-1 for CLIMAP). Regionally strong responses are induced by changes in SST gradients. Data-model comparisons indicate improvement in agreement relative to CLIMAP, but differences among terrestrial data inferences and simulated moisture and temperature remain. Our SSTs result in positive mass balance over the northern hemisphere ice sheets (primarily through reduced summer ablation), supporting the hypothesis that tropical and subtropical ocean temperatures may have played a role in triggering glacial changes at higher latitudes.

  15. Antipsychotics promote GABAergic interneuron genesis in the adult rat brain: Role of heat-shock protein production.

    PubMed

    Kaneta, Hiroo; Ukai, Wataru; Tsujino, Hanako; Furuse, Kengo; Kigawa, Yoshiyasu; Tayama, Masaya; Ishii, Takao; Hashimoto, Eri; Kawanishi, Chiaki

    2017-09-01

    Current antipsychotics reduce positive symptoms and reverse negative symptoms in conjunction with cognitive behavioral issues with the goal of restoring impaired occupational and social functioning. However, limited information is available on their influence on gliogenesis or their neurogenic properties in adult schizophrenia brains, particularly on GABAergic interneuron production. In the present study, we used young adult subventricular zone (SVZ)-derived progenitor cells expressing proteoglycan NG2 cultures to examine the oligodendrocyte and GABAergic interneuron genesis effects of several kinds of antipsychotics on changes in differentiation function induced by exposure to the NMDA receptor antagonist MK-801. We herein demonstrated that antipsychotics promoted or restored changes in the oligodendrocyte/GABAergic interneuron differentiation functions of NG2(+) cells induced by the exposure to MK-801, which was considered to be one of the drug-induced schizophrenia model. We also demonstrated that antipsychotics restored heat-shock protein (HSP) production in NG2(+) cells with differentiation impairment. The antipsychotics olanzapine, aripiprazole, and blonanserin, but not haloperidol increased HSP90 levels, which were reduced by the exposure to MK-801. Our results showed that antipsychotics, particularly those recently synthesized, exerted similar GABAergic interneuron genesis effects on NG2(+) neuronal/glial progenitor cells in the adult rat brain by increasing cellular HSP production, and also suggest that HSP90 may play a crucial role in the pathophysiology of schizophrenia and is a key target for next drug development. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Large scale features and energetics of the hybrid subtropical low `Duck' over the Tasman Sea

    NASA Astrophysics Data System (ADS)

    Pezza, Alexandre Bernardes; Garde, Luke Andrew; Veiga, José Augusto Paixão; Simmonds, Ian

    2014-01-01

    New aspects of the genesis and partial tropical transition of a rare hybrid subtropical cyclone on the eastern Australian coast are presented. The `Duck' (March 2001) attracted more recent attention due to its underlying genesis mechanisms being remarkably similar to the first South Atlantic hurricane (March 2004). Here we put this cyclone in climate perspective, showing that it belongs to a class within the 1 % lowest frequency percentile in the Southern Hemisphere as a function of its thermal evolution. A large scale analysis reveals a combined influence from an existing tropical cyclone and a persistent mid-latitude block. A Lagrangian tracer showed that the upper level air parcels arriving at the cyclone's center had been modified by the blocking. Lorenz energetics is used to identify connections with both tropical and extratropical processes, and reveal how these create the large scale environment conducive to the development of the vortex. The results reveal that the blocking exerted the most important influence, with a strong peak in barotropic generation of kinetic energy over a large area traversed by the air parcels just before genesis. A secondary peak also coincided with the first time the cyclone developed an upper level warm core, but with insufficient amplitude to allow for a full tropical transition. The applications of this technique are numerous and promising, particularly on the use of global climate models to infer changes in environmental parameters associated with severe storms.

  17. Influence of landscape position and transient water table on soil development and carbon distribution in a steep, headwater catchment

    Treesearch

    Scott W. Bailey; Patricia A. Brousseau; Kevin J. McGuire; Donald S. Ross

    2014-01-01

    Upland headwater catchments, such as those in the AppalachianMountain region, are typified by coarse textured soils, flashy hydrologic response, and low baseflow of streams, suggesting well drained soils and minimal groundwater storage. Model formulations of soil genesis, nutrient cycling, critical loads and rainfall/runoff response are typically based on vertical...

  18. Wave and Beach Processes Modeling for Sabine Pass to Galveston Bay, Texas, Shoreline Erosion Feasibility Study

    DTIC Science & Technology

    2007-08-01

    local wind field , led to the development of an appropriate alternative procedure which produced GENESIS results in agreement with observations...River field site wave data. ........................................................................................................53 Table 17...been abandoned since 1989 due to shoreline erosion. From east to west, the inlets in the study area include Sabine Pass, Rollover Pass near the

  19. A Reactive Transport Model for Marcellus Shale Weathering

    NASA Astrophysics Data System (ADS)

    Li, L.; Heidari, P.; Jin, L.; Williams, J.; Brantley, S.

    2017-12-01

    Shale formations account for 25% of the land surface globally. One of the most productive shale-gas formations is the Marcellus, a black shale that is rich in organic matter and pyrite. As a first step toward understanding how Marcellus shale interacts with water, we developed a reactive transport model to simulate shale weathering under ambient temperature and pressure conditions, constrained by soil chemistry and water data. The simulation was carried out for 10,000 years, assuming bedrock weathering and soil genesis began right after the last glacial maximum. Results indicate weathering was initiated by pyrite dissolution for the first 1,000 years, leading to low pH and enhanced dissolution of chlorite and precipitation of iron hydroxides. After pyrite depletion, chlorite dissolved slowly, primarily facilitated by the presence of CO2 and organic acids, forming vermiculite as a secondary mineral. A sensitivity analysis indicated that the most important controls on weathering include the presence of reactive gases (CO2 and O2), specific surface area, and flow velocity of infiltrating meteoric water. The soil chemistry and mineralogy data could not be reproduced without including the reactive gases. For example, pyrite remained in the soil even after 10,000 years if O2 was not continuously present in the soil column; likewise, chlorite remained abundant and porosity remained small with the presence of soil CO2. The field observations were only simulated successfully when the specific surface areas of the reactive minerals were 1-3 orders of magnitude smaller than surface area values measured for powdered minerals, reflecting the lack of accessibility of fluids to mineral surfaces and potential surface coating. An increase in the water infiltration rate enhanced weathering by removing dissolution products and maintaining far-from-equilibrium conditions. We conclude that availability of reactive surface area and transport of H2O and gases are the most important factors affecting chemical weathering of the Marcellus shale in the shallow subsurface. This study documents the utility of reactive transport modeling for complex subsurface processes. Such modelling could be extended to understand interactions between injected fluids and Marcellus shale gas reservoirs at higher temperature and pressure.

  20. Interactive Storytelling: From the Book of Genesis

    ERIC Educational Resources Information Center

    Park, Keith

    2004-01-01

    Keith Park, advisory teacher for Sense (the National Deafblind Rubella Association) in Greenwich and Lewisham, London, has written about his approach to interactive storytelling for BJSE before. This article describes a series of poetry workshops based on chapters 37 to 45 of the Book of Genesis (the story of Joseph and his family) using the text…

  1. Finding the Genesis for a Thesis

    ERIC Educational Resources Information Center

    Caroll, Joyce Armstrong

    2013-01-01

    This article describes a prewriting heuristics strategy that can help students find the genesis of their thesis. The 3 functions of the heuristic procedure are that it aids in retrieving relevant information stored in the mind; draws attention to important information that can be further researched or accessed; and prepares the mind for the…

  2. Tropical Cyclone Genesis Efficiency: Mid-Level Versus Bottom Vortex

    DTIC Science & Technology

    2011-12-16

    storm strength). Figure 4b shows the time evolutions of the corresponding maximum surface wind speed from the four experiments. Based on the definition...Pacific during summer. Mon. Wea. Rev., 124, 2245–2266. Chen, S. S. and W. M. Frank, 1993: A numerical study of the genesis of extratropical convective

  3. Anxiety Sensitivity and Panic Attacks: A 1-Year Longitudinal Study

    ERIC Educational Resources Information Center

    Li, Wen; Zinbarg, Richard E.

    2007-01-01

    The hypothesis that anxiety sensitivity (AS) is a risk factor for panic genesis has obtained compelling support, but the clinical/practical importance of AS in panic genesis has been questioned. In addition, the association between panic experience and AS increase has not been clearly demonstrated. Through this 1-year longitudinal study among…

  4. CognitiveGenesis (CG): Assessing Academic Achievement and Cognitive Ability in Adventist Schools

    ERIC Educational Resources Information Center

    Thayer, Jerome; Kido, Elissa

    2012-01-01

    CognitiveGenesis collected achievement and ability test data from 2006-2009 for all students in Seventh-day Adventist schools in North America. Students were above average in achievement compared to national norms and achieved above that predicted by their ability scores. The more years students attended Adventist schools, the higher they…

  5. Mutual Elements and Substrate Effect Analysis on Patch Antenna Arrays

    NASA Astrophysics Data System (ADS)

    Wallace, Matthew J.

    There have been many different technology advancements with the invention of solid state electronics, leading to the digital era which has changed the way users employ electronic circuits. Antennas are no different; however, they are still analog devices. With the advancements in technology, antennas are being fabricated on much higher frequencies and with greater bandwidths, all while trying to keep size and weight to a minimum. Centimeter and millimeter wave technologies have evolved for many different radio frequency (RF) applications. Microstrip patch antennas have been developed, as wire and tubular antenna elements are difficult to fabricate with the tolerances required at micro-wavelengths. Microstrip patch antennas are continuously being improved. These types of antennas are great for embedded or conformal applications where size and weight are of the essence and the ease of manufacturing elements to tight tolerances is important. One of the greatest benefits of patch antennas is the ease in creating an array. Many simulation programs have been created to assist in the design of patch antennas and arrays. However, there are still discrepancies between simulated results and actual measurements. This research will focus on these differences. It begins with a literature research of patch antenna design, followed by an assessment of simulation programs used for patch antenna design. The resulting antenna design was realized by the fabrication of an antenna from the Genesys software. Laboratory measurements of the real-world antenna are then compared to the theoretical antenna characteristics. This process is used to illustrate deficiencies in the software models and likely improvements that need to be made.

  6. Paleomagnetic Constraints on the age of the Lisheen Zn-Pb Deposit, Ireland: A Pre- Variscan Metamorphosed "MVT" Versus an Epigenetic Variscan Model for Ore Genesis

    NASA Astrophysics Data System (ADS)

    Pannalal, S. J.; Symons, D. T.; Sangster, D. F.

    2009-05-01

    Lower Carboniferous carbonate units in the Irish Midlands host major Zn-Pb ore deposits in two units, the Navan Group and the Waulsortian Limestone. The age and, therefore, the genesis of these ore deposits remains controversial because of the lack of absolute geochronological constraints. In addition, the effect of the Early Permian Variscan thermal episode, observed by elevated conodont color alteration indices in all Carboniferous strata in Ireland, on the Zn-Pb ore deposits is not clearly understood. This paleomagnetic study was undertaken to date and, thereby, constrain the genesis of the Waulsortian Limestone-hosted Lisheen Zn- Pb ore deposit. Specimens (432) from 12 sites in ore mineralization and 10 sites in host rocks at Lisheen were subjected to alternating-field and thermal step demagnetization protocols. Analysis of these specimens isolated a well-defined stable shallow and southerly-up paleomagnetic characteristic remanent magnetization (ChRM) direction. Saturation remanence tests, thermal decay data, and a paleomagnetic tilt test indicate a post-folding ChRM that is carried dominantly by single-domain magnetite. The ChRM directions from 8 host rock and 11 Zn-Pb mineralized sites are indistinguishable at 95% confidence, and give a mean paleopole at 41.6° S, 18.8° W (dp = 1.7°, dm = 3.3° ) with a paleomagnetic age of 277 ± 7 (2 σ) Ma on the apparent polar wander path for Laurentia in European coordinates. This Early Permian magnetization postdates peak-Variscan orogenic heating to ˜ 350° C in the surrounding region, suggesting two basic genetic models for Lisheen's Zn-Pb mineralization i.e. Variscan and metamorphosed pre-Variscan. The Variscan model, our preferred interpretation, suggests that the Zn-Pb mineralizing event occurred at 277 Ma during cooling from the regional Variscan thermal episode. This model, in conjunction with other thermal data, supports an entirely epigenetic origin that invokes a topographically-driven fluid flow, either from the south of Ireland or from closer to the deposit, that was modified by localized convection during the Variscan Orogeny. In contrast, the pre-Variscan model - favoured by previous authors - requires heating of the original Carboniferous Zn-Pb deposit to temperatures equivalent to chlorite-facies greenschist metamorphism during the Variscan Orogeny.

  7. Quantitative Modeling of Virus Evolutionary Dynamics and Adaptation in Serial Passages Using Empirically Inferred Fitness Landscapes

    DTIC Science & Technology

    2014-01-01

    decrease in virus count. This overall behavior of total species count (uninfected cells and viruses of all genotypes) shown in Fig. 1 was qualitatively...respiratory syndrome corona - virus host range expansion in human airway epithelium. J. Virol. 82: 2274 –2285. http://dx.doi.org/10.1128/JVI.02041-07...2008.12.014. 44. Bouvier NM, Lowen AC. 2010. Animal models for influenza virus patho- genesis and transmission. Viruses 2:1530 –1563. http

  8. Comparison of Probabilistic Coastal Inundation Maps Based on Historical Storms and Statistically Modeled Storm Ensemble

    NASA Astrophysics Data System (ADS)

    Feng, X.; Sheng, Y.; Condon, A. J.; Paramygin, V. A.; Hall, T.

    2012-12-01

    A cost effective method, JPM-OS (Joint Probability Method with Optimal Sampling), for determining storm response and inundation return frequencies was developed and applied to quantify the hazard of hurricane storm surges and inundation along the Southwest FL,US coast (Condon and Sheng 2012). The JPM-OS uses piecewise multivariate regression splines coupled with dimension adaptive sparse grids to enable the generation of a base flood elevation (BFE) map. Storms are characterized by their landfall characteristics (pressure deficit, radius to maximum winds, forward speed, heading, and landfall location) and a sparse grid algorithm determines the optimal set of storm parameter combinations so that the inundation from any other storm parameter combination can be determined. The end result is a sample of a few hundred (197 for SW FL) optimal storms which are simulated using a dynamically coupled storm surge / wave modeling system CH3D-SSMS (Sheng et al. 2010). The limited historical climatology (1940 - 2009) is explored to develop probabilistic characterizations of the five storm parameters. The probability distributions are discretized and the inundation response of all parameter combinations is determined by the interpolation in five-dimensional space of the optimal storms. The surge response and the associated joint probability of the parameter combination is used to determine the flood elevation with a 1% annual probability of occurrence. The limited historical data constrains the accuracy of the PDFs of the hurricane characteristics, which in turn affect the accuracy of the BFE maps calculated. To offset the deficiency of limited historical dataset, this study presents a different method for producing coastal inundation maps. Instead of using the historical storm data, here we adopt 33,731 tracks that can represent the storm climatology in North Atlantic basin and SW Florida coasts. This large quantity of hurricane tracks is generated from a new statistical model which had been used for Western North Pacific (WNP) tropical cyclone (TC) genesis (Hall 2011) as well as North Atlantic tropical cyclone genesis (Hall and Jewson 2007). The introduction of these tracks complements the shortage of the historical samples and allows for more reliable PDFs required for implementation of JPM-OS. Using the 33,731 tracks and JPM-OS, an optimal storm ensemble is determined. This approach results in different storms/winds for storm surge and inundation modeling, and produces different Base Flood Elevation maps for coastal regions. Coastal inundation maps produced by the two different methods will be discussed in detail in the poster paper.

  9. Phenomenology based multiscale models as tools to understand cell membrane and organelle morphologies

    PubMed Central

    Ramakrishnan, N.; Radhakrishnan, Ravi

    2016-01-01

    An intriguing question in cell biology is “how do cells regulate their shape?” It is commonly believed that the observed cellular morphologies are a result of the complex interaction among the lipid molecules (constituting the cell membrane), and with a number of other macromolecules, such as proteins. It is also believed that the common biophysical processes essential for the functioning of a cell also play an important role in cellular morphogenesis. At the cellular scale—where typical dimensions are in the order of micrometers—the effects arising from the molecular scale can either be modeled as equilibrium or non-equilibrium processes. In this chapter, we discuss the dynamically triangulated Monte Carlo technique to model and simulate membrane morphologies at the cellular scale, which in turn can be used to investigate several questions related to shape regulation in cells. In particular, we focus on two specific problems within the framework of isotropic and anisotropic elasticity theories: namely, (i) the origin of complex, physiologically relevant, membrane shapes due to the interaction of the membrane with curvature remodeling proteins, and (ii) the genesis of steady state cellular shapes due to the action of non-equilibrium forces that are generated by the fission and fusion of transport vesicles and by the binding and unbinding of proteins from the parent membrane. PMID:27087801

  10. Thermal alteration experiments on organic matter in recent marine sediments as a model for petroleum genesis

    NASA Technical Reports Server (NTRS)

    Baedecker, M. J.; Ikan, R.; Ishiwatari, R.; Kaplan, I. R.

    1977-01-01

    The fate of naturally occurring lipids and pigments in a marine sediment exposed to elevated temperatures was studied. Samples of a young marine sediment from Tanner Basin, California, were heated to a series of temperatures (65-200 C) for varying periods of time (7-64 days). The sediment was analyzed prior to and after heating for pigments, isoprenoid compounds, alcohols, fatty acids, and hydrocarbons. Structural changes caused by heating unextractable organic material (kerogen) were also studied, and the significance of the results for understanding petroleum genesis is considered. Among other results, fatty acids and hydrocarbons increased in abundance although there appeared to be no obvious precursor-to-product relationship via simple decarboxylation reactions. Chlorins were partially converted into porphyrins. The phytyl side chain of pheophytin was initially preserved intact by reduction of the phytyl double bond, but later converted to a variety of isoprenoid compounds including alkanes. Thermal grafting of components onto kerogen occurred as well as structural changes caused by heat.

  11. Groundwater sapping valleys: Experimental studies, geological controls and implications to the interpretation of valley networks on Mars

    NASA Technical Reports Server (NTRS)

    Kochel, R. Craig

    1988-01-01

    An integrated approach using experimental laboratory models, field studies of terrestrial analogs, and remote studies of terrestrial field sites were applied to the goals of understanding the nature and morphology of valley networks formed by groundwater sapping. In spite of problems with scaling, the experimental studies provide valuable insights into concepts relating to the initiation, development, and evolution of valleys by groundwater sapping. These investigations are also aimed at developing geomorphic criteria for distinguishing valleys formed by surface runoff from those formed by groundwater sapping processes. Channels that were field classified as sapping vs. runoff were successfully distinguished using statistical analysis of their respective morphologies; therefore, it may be possible to use similar techniques to interpret channel genesis on Mars. The terrestrial and flume studies provide the ground truth dataset which can be used (and will be during the present year) to help interpret the genesis of valley networks on Mars.

  12. Global warming hiatus contributed to the increased occurrence of intense tropical cyclones in the coastal regions along East Asia.

    PubMed

    Zhao, Jiuwei; Zhan, Ruifen; Wang, Yuqing

    2018-04-16

    The recent global warming hiatus (GWH) was characterized by a La Niña-like cooling in the tropical Eastern Pacific accompanied with the Indian Ocean and the tropical Atlantic Ocean warming. Here we show that the recent GWH contributed significantly to the increased occurrence of intense tropical cyclones in the coastal regions along East Asia since 1998. The GWH associated sea surface temperature anomalies triggered a pair of anomalous cyclonic and anticyclonic circulations and equatorial easterly anomalies over the Northwest Pacific, which favored TC genesis and intensification over the western Northwest Pacific but suppressed TC genesis and intensification over the southeastern Northwest Pacific due to increased vertical wind shear and anticyclonic circulation anomalies. Results from atmospheric general circulation model experiments demonstrate that the Pacific La Niña-like cooling dominated the Indian Ocean and the tropical Atlantic Ocean warming in contributing to the observed GWH-related anomalous atmospheric circulation over the Northwest Pacific.

  13. Testing the sensitivity of snowpack to climatic change in a large physiographically diverse watershed

    NASA Astrophysics Data System (ADS)

    MacDonald, R. J.; Byrne, J. M.; Kienzle, S. W.; Sauchyn, D.

    2009-12-01

    Snowpack in mountain watersheds provide a large portion of fresh water for many human and ecosystem function. Given the sensitivity of snow processes to temperature, it is likely that available water from snowpack will be reduced under future climate warming. It is important to understand how mountain environments will respond to changes in climate in order to properly manage water future resources. In order to assess potential changes in mountain snowpack and subsequent effects on water supply, we use a combination of hydrometeorological and general circulation models (GCMs). This work describes the application of the GENESYS (GENerate Earth SYstems Science input) spatial hydrometeorological model in simulating potential future changes in snowpack for the North Saskatchewan River watershed, Alberta. Snowpack in the North Saskatchewan River watershed supplies fresh water for over one million people and supports a wide range of ecosystem processes. To assess how snowpack may change in the watershed, scenarios from five GCMs are applied by perturbing the 1961-90 time series with mean changes in temperature and precipitation for the 2010-39, 2040-69 and 2070-99 periods. This study demonstrates that snowpack in the North Saskatchewan River watershed is highly susceptible to climate change and adaptive management strategies should be implemented to ensure sustainable water resources in the region.

  14. Redesigning Task Sequences to Support Instrumental Genesis in the Use of Movable Points and Slider Bars

    ERIC Educational Resources Information Center

    Fahlgren, Maria

    2017-01-01

    This paper examines the process of instrumental genesis through which students develop their proficiency in making use of movable points and slider bars--two tools that dynamic mathematics software provides for working with variable coordinates and parameters in the field of functions. The paper analyses students' responses to task sequences…

  15. The Instrumental Genesis Process in Future Primary Teachers Using Dynamic Geometry Software

    ERIC Educational Resources Information Center

    Ruiz-López, Natalia

    2018-01-01

    This paper, which describes a study undertaken with pairs of future primary teachers using GeoGebra software to solve geometry problems, includes a brief literature review, the theoretical framework and methodology used. An analysis of the instrumental genesis process for a pair participating in the case study is also provided. This analysis…

  16. ALTERED RA SIGNALING IN THE GENESIS OF ETHANOL-INDUCED LIMB DEFECTS

    EPA Science Inventory

    Altered RA Signaling in the Genesis of Ethanol-Induced Limb Defects

    Johnson CS(1), Sulik KK(1,2) Hunter, ES III(3)
    (1) Dept of Cell and Developmental Biology, UNC-Chapel Hill (2) Bowles Center for Alcohol Studies, UNC-CH (3) NHEERL, ORD, US EPA, RTP, NC

    Administr...

  17. Taking an Instrumental Genesis Lens: New Insights into Collaborative Mobile Learning

    ERIC Educational Resources Information Center

    Cerratto Pargman, Teresa; Nouri, Jalal; Milrad, Marcelo

    2018-01-01

    In this paper, we argue that in order to gain a deeper understanding of collaborative mobile learning in schools, it is important to know not only how mobile devices affect collaborative learning but also how collaborative learning emerges and is mediated by these devices. We develop our argument by applying the instrumental genesis theory and the…

  18. Learning Mathematics in a CAS Environment: The Genesis of a Reflection about Instrumentation and the Dialectics between Technical and Conceptual Work.

    ERIC Educational Resources Information Center

    Artigue, Michele

    2002-01-01

    Presents an anthropological approach used in French research and the theory of instrumentation developed in cognitive ergonomics. Shows how these frameworks allow an approach to the educational use of CAS technology, focusing on the unexpected complexity of instrumental genesis, mathematical needs of instrumentation, status of instrumented…

  19. 76 FR 21403 - Notice of Availability of the Final Environmental Impact Statement for the Genesis Project...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-15

    .... Idaho Street, Elko, Nevada during regular business hours of 7:30 a.m. to 4:30 p.m., Monday through... to contact the above individual during normal business hours. The FIRS is available 24 hours a day, 7... normal business hours. SUPPLEMENTARY INFORMATION: Newmont Mining Corporation's Genesis- Bluestar mining...

  20. Dividing the Concentrator Target From the Genesis Mission

    NASA Technical Reports Server (NTRS)

    Lauer, H. V., Jr.; Burkett, P. J.; Clemett, S. J.; Gonzales, C. P.; Nakamura-Messenger, K.; Rodriquez, M. C.; See, T. H.; Sutter, B.

    2014-01-01

    The Genesis spacecraft, launched in 2001, traveled to a Lagrangian point between the Earth and Sun to collect particles from the solar wind and return them to Earth. However, during the return of the spacecraft in 2004, the parachute failed to open during descent, and the Genesis spacecraft crashed into the Utah desert. Many of the solar wind collectors were broken into smaller pieces, and the field team rapidly collected the capsule and collector pieces for later assessment. On each of the next few days, the team discovered that various collectors had survived intact, including three of four concentrator targets. Within a month, the team had imaged more than 10,000 fragments and packed them for transport to the Astromaterials Acquisition and Curation Office within the ARES Directorate at JSC. Currently, the Genesis samples are curated along with the other extraterrestrial sample collections within ARES. Although they were broken and dirty, the Genesis solar wind collectors still offered the science community the opportunity to better understand our Sun and the solar system as a whole. One of the more highly prized concentrator collectors survived the crash almost completely intact. The Genesis Concentrator was designed to concentrate the solar wind by a factor of at least 20 so that solar oxygen and nitrogen isotopes could be measured. One of these materials was the Diamond-on-Silicon (DoS) concentrator target. Unfortunately, the DoS concentrator broke on impact. Nevertheless, the scientific value of the DoS concentrator target was high. The Genesis Allocation Committee received a request for approximately 1 cm(sup 2) of the DoS specimen taken near the focal point of the concentrator for the analysis of solar wind nitrogen isotopes. The largest fragment, Genesis sample 60000, was designated for this allocation and needed to be precisely cut. The requirement was to subdivide the designated sample in a manner that prevented contamination of the sample and minimized the risk of losing or breaking the precious requested sample fragment. The Genesis curator determined that the use of laser scribing techniques to "cut" a precise line and subsequently cleave the sample (in a controlled break of the sample along that line) was the best method for accomplishing the sample subdivision. However, there were risks, including excess heating of the sample, that could cause some of the implanted solar wind to be lost via thermal diffusion. Accidentally breaking the sample during the handling and cleaving process was an additional risk. Early in fiscal year 2013, to address this delicate, complicated task, the ARES Directorate assembled its top scientists to develop a cutting plan that would ensure success when applied to the actual concentrator target wafer; i.e., to produce an approximately 1 cm(sup 2) piece from the requested area of the wafer. The team, subsequently referred to as the JSC Genesis Tiger Team, spent months researching and testing parameters and techniques related to scribing, cleaving, transporting, handling, and holding (i.e., mounting) the specimen. The investigation required considerable "thinking outside the box," and many, many trials using nonflight wafer analogs. After all preliminary testing, the following method was adopted as the final cutting plan. It was used in two final end-to-end practice runs before being used on the actual flight target wafer. The wafer was oriented on the laser cutting stage with the 100 and 010 directions of the wafer parallel to the corresponding X and Y directions of the cutting stage. The laser was programed to scribe 31 lines of the appropriate length along the Y stage direction. The programed scribe lines were separated by 5 micron in the X direction. The laser parameters were set as follows: (1) The laser power was 0.5 watts; (2) each line consisted of 50 passes, with the Z position being advanced 5 micron per pass; and (3) 30 s would elapse before the next line was scribed to allow for wafer cool down from any possible heating via the laser. The ablated material that "stuck" in the "scribe-cut" was removed from the "cut" using an ultrasonic micro-tool. After all the ablated silicon was removed from the wafer, the wafer was repositioned in exactly the same orientation on the laser stage. The laser was focused using the bottom of the wafer channel, and the 31-line scribing pattern described above was reprogrammed using the Z position of the groove bottom as the starting Z value instead of the top wafer surface, which was used previously. Upon completion of the second set of scribes, the ultrasonic micro-tool was again used to clean out the cut. The wafer was remounted on the stage in exactly the same orientation as before. The laser was again focused on the bottom of the groove. This time, however, the laser was.programed to scribe only one line down the exact center of the channel. The final scribe line consisted of 100 passes with a Z advance of 5 micron per pass and with the laser power set at 0.5 watts. As mentioned above, the final cutting plan was practiced in two end-to-end trials using non-flight, triangular-shaped silicon wafers similar in size and orientation to the actual DOS 60000 target sample. The actual scribing of the triangular-shaped wafers required scribing two lines and cleaving (i.e. scribe-cleave, then scribe-cleave) to obtain the piece requested for allocation. Early in December 2012, after many months of experiments and practicing and perfecting the techniques and procedures, the team successfully subdivided the Genesis DoS 60000 target sample, one of the most scientifically important samples from the Genesis mission (figure 2). On December 17, 2012, the allocated piece of concentrator target sample was delivered to the requesting principal investigator.The cutting plan developed for the subdivision of this sample will be used as the model for subdividing future requested Genesis flight wafers (appropriately modified for different wafer types).

  1. Electrical Characteristics of Simulated Tornadoes and Dust Devils

    NASA Technical Reports Server (NTRS)

    Zimmerman, Michael I.; Farrell, William M.; Barth, E. L.; Lewellen, W. S.; Perlongo, N. J.; Jackson, T. L.

    2012-01-01

    It is well known that tornadoes and dust devils have the ability to accumulate significant, visible clouds of debris. Collisions between sand-like debris species produce different electric charges on different types of grains, which convect along different trajectories around the vortex. Thus, significant charge separations and electric currents are possible, which as the vortex fluctuates over time are thought to produce ULF radiation signatures that have been measured in the field. These electric and magnetic fields may contain valuable information about tornado structure and genesis, and may be critical in driving electrochemical processes within dust devils on Mars. In the present work, existing large eddy simulations of debris-laden tornadoes performed at West Virginia University are coupled with a new debris-charging and advection code developed at Goddard Space Flight Center to investigate the detailed (meter-resolution) fluid-dynamic origins of electromagnetic fields within terrestrial vortices. First results are presented, including simulations of the electric and magnetic fields that would be observed by a near-surface, instrument-laden probe during a direct encounter with a tornado.

  2. Ginsenoside Rb1 improves spatial learning and memory by regulation of cell genesis in the hippocampal subregions of rats.

    PubMed

    Liu, Lei; Hoang-Gia, Trinh; Wu, Hui; Lee, Mi-Ra; Gu, Lijuan; Wang, Chunyan; Yun, Beom-Sik; Wang, Qijun; Ye, Shengquan; Sung, Chang-Keun

    2011-03-25

    Ginsenoside Rb1 (Rb1) is known to improve learning and memory in hippocampus-dependent tasks. However, the cellular mechanism remains unknown. Cell genesis in hippocampus is involved in spatial learning and memory. In the present study, Rb1 was orally administrated to adult rats for 30days. The behavioral training tests indicated that Rb1 improved spatial cognitive performance of rats in Morris water maze (MWM). Furthermore, we investigated the effects of Rb1 on cell genesis in adult rats' hippocampus, using thymidine analog bromodeoxyuridine (BrdU) as a marker for dividing cells. It has been shown that hippocampal cell genesis can be influenced by several factors such as learning and exercise. In order to avoid the effects of the interfering factors, only the rats treated with Rb1 without training in MWM were used to investigate cell genesis in hippocampus. When BrdU was given to the rats 30days prior to being killed, it was shown that oral administration of Rb1 significantly increased cell survival in dentate gyrus and hippocampal subregion CA3. However, when BrdU was injected 2h prior to sacrifice, the results indicated that Rb1 had no significant influence on cell proliferation in the hippocampal subregions. Thus, an increase of cell survival in hippocampus stimulated by Rb1 may be one of the mechanisms by which ginseng facilitates spatial learning and memory. Our study also indicates that Rb1 may be developed as a therapeutic agent for patients with memory impairment. Copyright © 2011 Elsevier B.V. All rights reserved.

  3. The bioinformatics of nucleotide sequence coding for proteins requiring metal coenzymes and proteins embedded with metals

    NASA Astrophysics Data System (ADS)

    Tremberger, G.; Dehipawala, Sunil; Cheung, E.; Holden, T.; Sullivan, R.; Nguyen, A.; Lieberman, D.; Cheung, T.

    2015-09-01

    All metallo-proteins need post-translation metal incorporation. In fact, the isotope ratio of Fe, Cu, and Zn in physiology and oncology have emerged as an important tool. The nickel containing F430 is the prosthetic group of the enzyme methyl coenzyme M reductase which catalyzes the release of methane in the final step of methano-genesis, a prime energy metabolism candidate for life exploration space mission in the solar system. The 3.5 Gyr early life sulfite reductase as a life switch energy metabolism had Fe-Mo clusters. The nitrogenase for nitrogen fixation 3 billion years ago had Mo. The early life arsenite oxidase needed for anoxygenic photosynthesis energy metabolism 2.8 billion years ago had Mo and Fe. The selection pressure in metal incorporation inside a protein would be quantifiable in terms of the related nucleotide sequence complexity with fractal dimension and entropy values. Simulation model showed that the studied metal-required energy metabolism sequences had at least ten times more selection pressure relatively in comparison to the horizontal transferred sequences in Mealybug, guided by the outcome histogram of the correlation R-sq values. The metal energy metabolism sequence group was compared to the circadian clock KaiC sequence group using magnesium atomic level bond shifting mechanism in the protein, and the simulation model would suggest a much higher selection pressure for the energy life switch sequence group. The possibility of using Kepler 444 as an example of ancient life in Galaxy with the associated exoplanets has been proposed and is further discussed in this report. Examples of arsenic metal bonding shift probed by Synchrotron-based X-ray spectroscopy data and Zn controlled FOXP2 regulated pathways in human and chimp brain studied tissue samples are studied in relationship to the sequence bioinformatics. The analysis results suggest that relatively large metal bonding shift amount is associated with low probability correlation R-sq outcome in the bioinformatics simulation.

  4. Grants: Genesis of Some Funded Proposal Ideas

    ERIC Educational Resources Information Center

    Pazdar, John

    2011-01-01

    While "thinking outside the box" can be an over-used phase at times, in the world of grants it can provide the genesis of ideas. The "box" is the world of academia accepted by most educators, while "thinking outside" is the process that leads to grant ideas. In the grant world, "thinking outside the box" is a process of doing something that has…

  5. Large-Scale Professional Development towards Emancipatory Mathematics: The Genesis of YuMi Deadly Maths

    ERIC Educational Resources Information Center

    Cooper, Tom; Carter, Merilyn

    2016-01-01

    This paper describes the genesis of YuMi Deadly Maths, a school change process that has been used in over 200 schools to develop mathematics teaching and learning to improve students' employment and life chances. The paper discusses the YuMi Deadly Maths approach to mathematics content and pedagogy, implemented through a process of PD and school…

  6. Genesis of Influenza A(H5N8) Viruses.

    PubMed

    El-Shesheny, Rabeh; Barman, Subrata; Feeroz, Mohammed M; Hasan, M Kamrul; Jones-Engel, Lisa; Franks, John; Turner, Jasmine; Seiler, Patrick; Walker, David; Friedman, Kimberly; Kercher, Lisa; Begum, Sajeda; Akhtar, Sharmin; Datta, Ashis Kumar; Krauss, Scott; Kayali, Ghazi; McKenzie, Pamela; Webby, Richard J; Webster, Robert G

    2017-08-01

    Highly pathogenic avian influenza A(H5N8) clade 2.3.4.4 virus emerged in 2016 and spread to Russia, Europe, and Africa. Our analysis of viruses from domestic ducks at Tanguar haor, Bangladesh, showed genetic similarities with other viruses from wild birds in central Asia, suggesting their potential role in the genesis of A(H5N8).

  7. Cosmogonies and Culture: Teaching Genesis and the Popol Vuh in an Interdisciplinary Course at a Christian University

    ERIC Educational Resources Information Center

    Parsons, Mikeal C.; Cook, Garrett

    2004-01-01

    This paper explores the possibilities of teaching Genesis and the Popol Vuh, the Mayan creation account, in an interdisciplinary course at a church-related institution. The course is part of an alternative, interdisciplinary core curriculum typically taken by two hundred students a year at the university. A comparison of the Popol Vuh with Genesis…

  8. Modulation of Molecular Markers by CLA.

    DTIC Science & Technology

    1995-10-01

    greater benefit in cancer protection. 16 Discussion CLA is not the only fatty acid known to inhibit carcinogenesis. Eicosapentaenoic acid and...public release; distribution unlimited 13. ABSTRACT (Maximum200words) Conjugated linoleic acid (CLA) is a naturally occurring com- ponent of the food...events leading to the genesis of breast cancer. 14. SUBJECT TERMS 15. NUMBER OF PAGES Conjugated linoleic acid , mafmiary carcino- 58 genesis

  9. Power and Energy Storage Requirements for Ship Integration of Solid-State Lasers on Naval Platforms

    DTIC Science & Technology

    2016-06-01

    output power is varied. 14. SUBJECT TERMS energy storage, lithium - ion batteries , lead acid batteries , atmospheric propagation, laser, ANCHOR 15...XE 70 Genesis battery (lead acid) .............................................................24 Figure 12. Saft VL 30 PFe lithium ion battery ...19 Table 6. Properties of lead acid battery Genesis XE 70...........................................25 Table 7. Properties of lithium - ion

  10. Molecular Contamination on Anodized Aluminum Components of the Genesis Science Canister

    NASA Technical Reports Server (NTRS)

    Burnett, D. S.; McNamara, K. M.; Jurewicz, A.; Woolum, D.

    2005-01-01

    Inspection of the interior of the Genesis science canister after recovery in Utah, and subsequently at JSC, revealed a darkening on the aluminum canister shield and other canister components. There has been no such observation of film contamination on the collector surfaces, and preliminary spectroscopic ellipsometry measurements support the theory that the films observed on the anodized aluminum components do not appear on the collectors to any significant extent. The Genesis Science Team has made an effort to characterize the thickness and composition of the brown stain and to determine if it is associated with molecular outgassing.Detailed examination of the surfaces within the Genesis science canister reveals that the brown contamination is observed to varying degrees, but only on surfaces exposed in space to the Sun and solar wind hydrogen. In addition, the materials affected are primarily composed of anodized aluminum. A sharp line separating the sun and shaded portion of the thermal closeout panel is shown. This piece was removed from a location near the gold foil collector within the canister. Future plans include a reassembly of the canister components to look for large-scale patterns of contamination within the canister to aid in revealing the root cause.

  11. Multicentric genesis of material structure: Development of the percolation model and some applications

    NASA Astrophysics Data System (ADS)

    Herega, Alexander; Sukhanov, Volodymyr; Vyrovoy, Valery

    2016-11-01

    The multiplicative measure and estimation method of ordering of the nearest neighborhood at the multiscale "site" percolation problem are considered. In the report also is shown the possibility of quantifying a relative degree of order of two nearest neighborhoods, which is based on the algorithm proposed by one of the authors. Moreover, the model of the oscillatory component of interaction of inner boundaries of different scales is proposed. In the context of our report, the concept of lacunarity and effective dimension (introduced by B. Mandelbrot) is discussed as effective tools of mathematical modeling.

  12. High Resolution Global Climate Modeling with GEOS-5: Intense Precipitation, Convection and Tropical Cyclones on Seasonal Time-Scales.

    NASA Technical Reports Server (NTRS)

    Putnam, WilliamM.

    2011-01-01

    In 2008 the World Modeling Summit for Climate Prediction concluded that "climate modeling will need-and is ready-to move to fundamentally new high-resolution approaches to capitalize on the seamlessness of the weather-climate continuum." Following from this, experimentation with very high-resolution global climate modeling has gained enhanced priority within many modeling groups and agencies. The NASA Goddard Earth Observing System model (GEOS-5) has been enhanced to provide a capability for the execution at the finest horizontal resolutions POS,SIOle with a global climate model today. Using this high-resolution, non-hydrostatic version of GEOS-5, we have developed a unique capability to explore the intersection of weather and climate within a seamless prediction system. Week-long weather experiments, to mUltiyear climate simulations at global resolutions ranging from 3.5- to 14-km have demonstrated the predictability of extreme events including severe storms along frontal systems, extra-tropical storms, and tropical cyclones. The primary benefits of high resolution global models will likely be in the tropics, with better predictions of the genesis stages of tropical cyclones and of the internal structure of their mature stages. Using satellite data we assess the accuracy of GEOS-5 in representing extreme weather phenomena, and their interaction within the global climate on seasonal time-scales. The impacts of convective parameterization and the frequency of coupling between the moist physics and dynamics are explored in terms of precipitation intensity and the representation of deep convection. We will also describe the seasonal variability of global tropical cyclone activity within a global climate model capable of representing the most intense category 5 hurricanes.

  13. CORSAIR Solar Energetic Particle Model

    NASA Astrophysics Data System (ADS)

    Sandroos, A.

    2013-05-01

    Acceleration of particles in coronal mass ejection (CME) driven shock waves is the most commonly accepted and best developed theory of the genesis of gradual solar energetic particle (SEP) events. The underlying acceleration mechanism is the diffusive shock acceleration (DSA). According to DSA, particles scatter from fluctuations present in the ambient magnetic field, which causes some particles to encounter the shock front repeatedly and to gain energy during each crossing. Currently STEREO and near-Earth spacecraft are providing valuable multi-point information on how SEP properties, such as composition and energy spectra, vary in longitude. Initial results have shown that longitude distributions of large CME-associated SEP events are much wider than reported in earlier studies. These findings have important consequences on SEP modeling. It is important to extend the present models into two or three spatial coordinates to properly take into account the effects of coronal and interplanetary (IP) magnetic geometry, and evolution of the CME and the associated shock, on the acceleration and transport of SEPs. We give a status update on CORSAIR project, which is an effort to develop a new self-consistent (total energy conserving) DSA acceleration model that is capable of modeling energetic particle acceleration and transport in IP space in two or three spatial dimensions. In the new model particles are propagated using guiding center approximation. Waves are modeled as (Lagrangian) wave packets propagating (anti)parallel to ambient magnetic field. Diffusion coefficients related to scattering from the waves are calculated using quasilinear theory. State of ambient plasma is obtained from an MHD simulation or by using idealized analytic models. CORSAIR is an extension to our earlier efforts to model the effects of magnetic geometry on SEP acceleration (Sandroos & Vainio, 2007,2009).

  14. Nuts and Bolts - Techniques for Genesis Sample Curation

    NASA Technical Reports Server (NTRS)

    Burkett, Patti J.; Rodriquez, M. C.; Allton, J. H.

    2011-01-01

    The Genesis curation staff at NASA Johnson Space Center provides samples and data for analysis to the scientific community, following allocation approval by the Genesis Oversight Committee, a sub-committee of CAPTEM (Curation Analysis Planning Team for Extraterrestrial Materials). We are often asked by investigators within the scientific community how we choose samples to best fit the requirements of the request. Here we will demonstrate our techniques for characterizing samples and satisfying allocation requests. Even with a systematic approach, every allocation is unique. We are also providing updated status of the cataloging and characterization of solar wind collectors as of January 2011. The collection consists of 3721 inventoried samples consisting of a single fragment, or multiple fragments containerized or pressed between post-it notes, jars or vials of various sizes.

  15. Doctor James Young Simpson, Rabbi Abraham De Sola, and Genesis Chapter 3, verse 16.

    PubMed

    Cohen, J

    1996-11-01

    When Dr. James Simpson began to use anesthesia in child-birth in 1846, a religious furor arose against its use. For many people, including many physicians, Genesis chapter 3, verse 16, implied that childbirth had to be a painful process. In 1849, the editors of one of Canada's medical journals asked Abraham De Sola, Canada's first rabbi, to give his interpretation of Genesis 3:16 for the benefit of their readers, which he did in a three-part article. Using Hebrew biblical scholars as his source, he wrote that the correct interpretation of this passage was that with toil or labor shall women bring forth children, rather than with pain. Therefore, by using anesthesia in childbirth, physicians were not going against the scriptures or the word of God.

  16. Reconstruction of the Genesis Entry

    NASA Technical Reports Server (NTRS)

    Desai, Prasun N.; Qualls, Garry D.; Schoenenberger, Mark

    2005-01-01

    This paper provides an overview of the findings from a reconstruction analysis of the Genesis capsule entry. First, a comparison of the atmospheric properties (density and winds) encountered during the entry to the pre-entry profile is presented. The analysis that was performed on the video footage (obtained from the tracking stations at UTTR) during the descent is then described from which the Mach number at the onset of the capsule tumble was estimated following the failure of the drogue parachute deployment. Next, an assessment of the Genesis capsule aerodynamics that was extracted from the video footage is discussed, followed by a description of the capsule hypersonic attitude that must have occurred during the entry based on examination of the recovered capsule heatshield. Lastly, the entry trajectory reconstruction that was performed is presented.

  17. Cleaning Surface Particle Contamination with Ultrapure Water (UPW) Megasonic Flow on Genesis Array Collectors

    NASA Technical Reports Server (NTRS)

    Allton, J. H.; Calaway, Michael J.; Hittle, J. D.; Rodriquez, M. C.; Stansbery, E. K.; McNamara, K. M.

    2006-01-01

    The hard landing experienced by the Genesis sample return capsule breached the science canister containing the solar wind collectors. This impact into the damp lakebed contaminated collector surfaces with pulverized collector and spacecraft materials and Utah sediment and brine residue. The gold foil, polished aluminum, and bulk metallic glass remained intact, but the solar wind bulk and regime-specific array collectors were jarred loose from their frames and fractured into greater than 10,000 specimens. After a year of investigation and cleaning experimentation, the Genesis Science Team determined that array collectors had 4 classes of contaminants: particles, molecular film, submicron inorganic particulate ("aerosol"), and pre-launch surface contamination. We discuss here use of megasonically energized ultrapure water (UPW) for removing particulate debris from array collector fragments.

  18. The evolution of the magmatic arc of Southern Peru (200-60 Ma), Arequipa area: insight from geochemical modeling

    NASA Astrophysics Data System (ADS)

    Demouy, S.; Benoit, M.; De Saint Blanquat, M.; Brunet, P.

    2012-12-01

    Cordilleran-type batholiths are built by prolonged arc activity along continental margins and may provide detailed magmatic records of the subduction system evolution. The magmas produced in subduction context involve both mantellic and crustal end members and are subject to various petrological processes. The MASH zones (Hildreth and Moorbath, 1988), at the basis of the continental crust, are the best places for the genesis of such hybrid magmas. The various geochemical signatures observed in the plutonic rocks, may also be attributed to source heterogeneities or generated by subsequent petrological processes. This study has focused in the Arequipa section of the Coastal Batholith of Southern Peru (200-60 Ma), in an area extending over 80x40 km. Major and trace elements as well as Sr and Nd isotopic analyses were performed in a set of 100 samples ranging from gabbro to granite. The obtained data highlight the wide heterogeneity of the geochemical signatures that is not related to the classification of the rocks. In first step, Rb/Sr systematic was used to isolate a set of samples plotting along a Paleocene isochron and defining a cogenetic suite. This suite appears to have evolved by simple fractional crystallization. By using reverse modeling, the parameters controlling the fractional crystallization process were defined, as partition coefficients, initial concentrations and amount of fractional crystallization. The other magmatic suites display a wide range of isotopic and geochemical signatures. To explain this heterogeneity, a model involving competition between fractional crystallization and magma mixing into MASH zones was proposed. A large range of hybrid magma types is potentially generated during the maturation of the system, but this range tends to disappear as fractionation and mixing occurs. Finally the model predicts the genesis of a homogeneous reservoir created at depth, from which magmas may evolve only by fractional crystallization. Therefore stabilization of this reservoir is directly related to the thermal conditions present at the basis of the continental crust, and allows the production of large volumes at the batholiths level, known as flare-up events. These results are critical in order to estimate the amount of crustal growth and thickening in the Arequipa area, as they provide the basis for the estimation of the mantle versus crustal contribution during the magma genesis.

  19. Hurricane genesis: on the breaking African easterly waves and critical layers

    NASA Astrophysics Data System (ADS)

    Asaadi, Ali; Brunet, Gilbert; Yau, Peter

    2015-04-01

    This study bring new understanding on the decades-old hurricane genesis problem that starts with westward travelling African easterly waves that can evolve into coherent cyclonic vortices depending on their strength and other nonlinear wave breaking processes. In general, observations indicate that only a small fraction of the African easterly waves that occur in a single hurricane season contribute to tropical cyclogenesis. However, this small fraction includes a large portion of named storms. In addition, a recent study by Dunkerton et al. (2009) has shown that named storms in the Atlantic and eastern Pacific basins are almost all associated with a cyclonic Kelvin "cat's eye" of a tropical easterly wave typical of critical layers, located equatorward of the easterly jet axis. To better understand the dynamics involved in hurricane genesis, the flow characteristics and the physical and dynamical mechanisms by which easterly waves form cat's eyes are investigated with the help of atmospheric reanalyzes and numerical simulations. We perform a climatological study of developing easterly waves covering the 1998-2001 hurricane seasons using ERA-Interim 6-hourly reanalysis data. Composite analyses for all named storms show a monotonic potential vorticity (PV) profile with weak meridional PV gradient and a cyclonic (i.e., south of the easterly jet axis) critical line for time periods of several days preceding the cat's eye formation. In addition, the developing PV anomaly composite shows a statistically significant companion wave-packet of non-developing easterly waves. A barotropic shallow water model is used to study the initial value and forced problems of disturbances on a parabolic jet and realistic profiles associated with weak basic state meridional PV gradients, leading to Kelvin cat's eye formation around the jet axis. The results highlight the synergy of the dynamical mechanisms, including wave breaking and PV redistribution within the nonlinear critical layer characterized by weak PV gradients, and the thermodynamical mechanisms such as convectively generated PV anomalies in the cat's eye formation in tropical cyclogenesis. These findings are consistent with the analytical theory of free and forced disturbances to an easterly parabolic jet (Brunet and Warn, 1990; Brunet and Haynes, 1995; Choboter et al., 2000). 1) Dunkerton, T. J., M. T. Montgomery, and Z. Wang, 2009: Tropical cyclogenesis in a tropical wave critical layer: Easterly waves. Atmos. Chem. Phys., 9, 5587-5646. 2) Brunet, G., and T. Warn, 1990: Rossby Wave Critical Layers on a Jet. J. Atmos. Sci., 47, 1173-1178. 3) Brunet, and P. H. Haynes, 1995: The Nonlinear Evolution of Disturbances to a Parabolic Jet. J. Atmos. Sci., 52, 464-477. 4) Choboter, P. F., G. Brunet, and S. A. Maslowe, 2000: Forced Disturbances in a Zero Absolute Vorticity Gradient Environment. J. Atmos. Sci., 57, 1406-1419.

  20. Localized Upper Tropospheric Warming During Tropical Depression and Storm Formation Revealed by the NOAA-15 AMSU

    NASA Technical Reports Server (NTRS)

    Spencer, Roy W.; Braswell, William D.

    1999-01-01

    The warm core of hurricanes as measured by microwave temperature sounders has been related to various azimuthally averaged measures of hurricane strength by several researchers Unfortunately, the use of these instruments (e.g. the Microwave Sounding Units, MSU) for the routine monitoring of tropical cyclone genesis and intensity has been hampered by poor resolution. The recent launch of the NOAA-15 AMSU represents a significant advance in our ability to monitor subtle atmospheric temperature variations (0.1-0.2 C) at relatively high spatial resolution (50 km) in the presence of clouds. Of particular interest is the possible capability of the AMSU to observe the slight warming associated with depression formation, and the relationship of the spatial characteristics of the warming to the surface pressure and wind field, without azimuthal averaging. In order to present the AMSU data as imagery, we have developed a method for precise limb-correction of all 15 AMSU channels. Through a linear combination of several neighboring channels, we can very closely match the nadir weighting functions of a given AMSU sounding channel with the non-nadir data. It is found that there is discernible, localized upper tropospheric warming associated with depression formation in the Atlantic basin during the 1998 hurricane season. Also, it is found that uncertainty in positioning of tropical cyclone circulation centers can be reduced, as in the example of Hurricane Georges as it approached Cuba. Finally, to explore the potential utility of a future high resolution microwave temperature sounder, we present an analysis of the relationship between the modeled surface wind field and simulated high -resolution AMSU-type measurements, based upon cloud resolving model simulations of hurricane Andrew in 1992.

  1. Response of winter North Atlantic storm track to climate change in the CNRM-CM5 simulations

    NASA Astrophysics Data System (ADS)

    Chauvin, Fabrice; Oudar, Thomas; Sanchez-Gomez, Emilia; Terray, Laurent

    2016-04-01

    Climate variability in Europe in winter is largely controlled by North Atlantic storm tracks. These are associated with transport of energy, momentum, and water vapour, between the equator and mid latitudes. Extratropical cyclones have caused severe damages over some regions in north-western Europe, since they can combine extreme precipitation and strong winds. This is why it is relevant to study the impact of climate change on the extratropical cyclones, principally on their intensity, position or lifespan. Indeed, several recent studies have focused on this subject by using atmospheric reanalysis and general circulation models (GCMs). The main conclusions from the CMIP3 simulations showed a decreasing of the total number of cyclones and a poleward shift of their tracks in response to global warming. In the recent CMIP5 exercise, the consensus is not so clear, probably due to more complex feedbacks acting in the different models. Thus, the question of changes in North Atlantic storm-tracks with warming remains open. The main goal of this work is to explore the changes in the North Atlantic storm-tracks in the past and future decades and to analyze the contributions of the different external forcings (natural and anthropogenic) versus the internal variability. On this purpose, we use the Detection and Attribution (D&A) simulations performed with the coupled model CNRM-CM5. To characterize the extratropical cyclones and their tracks, a tracking scheme based on the detection of maximum of relative vorticity at 850 hPa is conducted. We show that the coupled model fairly well reproduces the storm genesis locations as well as the tracks pathways comparing to several atmospheric reanalysis products. In the recent historical period (1950-2005), the model shows a decrease in the number of storms in the southern North-Atlantic, when all the forcings (anthropogenic and natural) are prescribed. Even if the role of internal variability is important in the last decades (the inter-members spread is very large), and the signals rarely emerge from the noise, analysis based on the Eady Growth Rate parameter has lead to quantify the respective roles of baroclinicity and meridional temperature gradients. Finally, in the scenario (RCP8.5), the tendency seen in the all-forcings historical run is confirmed and reinforced.

  2. Computer Menu Task Performance Model Development

    DTIC Science & Technology

    1990-11-01

    effect that all three of these factors have on menu task performance Results showed that all three factors significantly influenced menu search and...applications. The work was sponsored by the AFHRL Operations Training Division (AFHRL/OT) and performed under Work Unit 1123-34-02, User/System Interface...capabilities effectively are often either not available or configured in a manner that is difficult to use. These findings provided the genesis for the work

  3. The Genesis of Cyberscience and its Mathematical Models (CYBERSCIENCE)

    DTIC Science & Technology

    2005-02-01

    Of course, the idea of maintaining a complete development record has other advantages , and has frequently been proposed in the past as a solution to...system development. There is no question that this offers certain advantages . For exam- ple, if systems that satisfy a standard frequently prove...some substantial practical advantages . First, providing wildly 2Unfortunately, this terminology has not been standardized. For example, in the Safety

  4. Ionics of nanoheterogeneous materials

    NASA Astrophysics Data System (ADS)

    Uvarov, Nikolay F.

    2007-05-01

    The results of studies of composite ionic conductors are considered. The relationship between their properties and the ionic salt disordering and the interfacial interaction between the components of the material is analysed. Special attention is paid to models that describe the surface disordering and the mechanism of defect formation. The methods of calculation of physicochemical characteristics of composites, the thermodynamic stability and peculiarities of the genesis of the nanocomposite morphology are discussed.

  5. Cosmic clustering

    DOE PAGES

    Anninos, Dionysios; Denef, Frederik

    2016-06-30

    We show that the late time Hartle-Hawking wave function for a free massless scalar in a fixed de Sitter background encodes a sharp ultrametric structure for the standard Euclidean distance on the space of field configurations. This implies a hierarchical, tree-like organization of the state space, reflecting its genesis as a branched diffusion process. In conclusion, an equivalent mathematical structure organizes the state space of the Sherrington-Kirkpatrick model of a spin glass.

  6. Hydroclimatology of Extreme Precipitation and Floods Originating from the North Atlantic Ocean

    NASA Astrophysics Data System (ADS)

    Nakamura, Jennifer

    This study explores seasonal patterns and structures of moisture transport pathways from the North Atlantic Ocean and the Gulf of Mexico that lead to extreme large-scale precipitation and floods over land. Storm tracks, such as the tropical cyclone tracks in the Northern Atlantic Ocean, are an example of moisture transport pathways. In the first part, North Atlantic cyclone tracks are clustered by the moments to identify common traits in genesis locations, track shapes, intensities, life spans, landfalls, seasonal patterns, and trends. The clustering results of part one show the dynamical behavior differences of tropical cyclones born in different parts of the basin. Drawing on these conclusions, in the second part, statistical track segment model is developed for simulation of tracks to improve reliability of tropical cyclone risk probabilities. Moisture transport pathways from the North Atlantic Ocean are also explored though the specific regional flood dynamics of the U.S. Midwest and the United Kingdom in part three of the dissertation. Part I. Classifying North Atlantic Tropical Cyclones Tracks by Mass Moments. A new method for classifying tropical cyclones or similar features is introduced. The cyclone track is considered as an open spatial curve, with the wind speed or power information along the curve considered as a mass attribute. The first and second moments of the resulting object are computed and then used to classify the historical tracks using standard clustering algorithms. Mass moments allow the whole track shape, length and location to be incorporated into the clustering methodology. Tropical cyclones in the North Atlantic basin are clustered with K-means by mass moments producing an optimum of six clusters with differing genesis locations, track shapes, intensities, life spans, landfalls, seasonality, and trends. Even variables that are not directly clustered show distinct separation between clusters. A trend analysis confirms recent conclusions of increasing tropical cyclones in the basin over the past two decades. However, the trends vary across clusters. Part II: Tropical cyclone Intensity and Track Simulator (HITS) with Atlantic Ocean Applications for Risk Assessment. A nonparametric stochastic model is developed and tested for the simulation of tropical cyclone tracks. Tropical cyclone tracks demonstrate continuity and memory over many time and space steps. Clusters of tracks can be coherent, and the separation between clusters may be marked by geographical locations where groups of tracks diverge due to the physics of the underlying process. Consequently, their evolution may be non-Markovian. Markovian simulation models, as often used, may produce tracks that potentially diverge or lose memory quicker than nature. This is addressed here through a model that simulates tracks by randomly sampling track segments of varying length, selected from historical tracks. For performance evaluation, a spatial grid is imposed on the domain of interest. For each grid box, long-term tropical cyclone risk is assessed through the annual probability distributions of the number of storm hours, landfalls, winds, and other statistics. Total storm length is determined at birth by local distribution, and movement to other tropical cyclone segments by distance to neighbor tracks, comparative vector, and age of track. An assessment of the performance for tropical cyclone track simulation and potential directions for the improvement and use of such model are discussed. Part III: Dynamical Structure of Extreme Floods in the U.S. Midwest and the United Kingdom. Twenty extreme spring floods that occurred in the Ohio Basin between 1901 and 2008, identified from daily river discharge data, are investigated and compared to the April 2011 Ohio River flood event. Composites of synoptic fields for the flood events show that all these floods are associated with a similar pattern of sustained advection of low-level moisture and warm air from the tropical Atlantic Ocean and the Gulf of Mexico. The typical flow conditions are governed by an anomalous semi-stationary ridge situated east of the US East Coast, which steers the moisture and converges it into the Ohio Valley. Significantly, the moisture path common to all the 20 cases studied here as well as the case of April 2011 is distinctly different from the normal path of Atlantic moisture during spring, which occurs further west. It is shown further that the Ohio basin moisture convergence responsible for the floods is caused primarily by the atmospheric circulation anomaly advecting the climatological mean moisture field. Transport and related convergence due to the covariance between moisture anomalies and circulation anomalies are of secondary but non-negligible importance. The importance of atmospheric circulation anomalies to floods is confirmed by conducting a similar analysis for a series of winter floods on the River Eden in northwest England.

  7. Dynamics and Predictability of Tropical Cyclone Genesis, Structure and Intensity Change

    DTIC Science & Technology

    2012-09-30

    analyses and forecasts of tropical cyclones, including genesis, intensity change, and extratropical transition. A secondary objective is to understand... storm -centered assimilation algorithm. Basic research in Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the...COMPLETED For the four storms consider (Nuri, Jangmi, Sinlaku, and Hagupit), an 80-member EnKF has been cycled on observations (surface, rawinsondes, GPS

  8. Genesis of Influenza A(H5N8) Viruses

    PubMed Central

    El-Shesheny, Rabeh; Barman, Subrata; Feeroz, Mohammed M.; Hasan, M. Kamrul; Jones-Engel, Lisa; Franks, John; Turner, Jasmine; Seiler, Patrick; Walker, David; Friedman, Kimberly; Kercher, Lisa; Begum, Sajeda; Akhtar, Sharmin; Datta, Ashis Kumar; Krauss, Scott; Kayali, Ghazi; McKenzie, Pamela; Webby, Richard J.

    2017-01-01

    Highly pathogenic avian influenza A(H5N8) clade 2.3.4.4 virus emerged in 2016 and spread to Russia, Europe, and Africa. Our analysis of viruses from domestic ducks at Tanguar haor, Bangladesh, showed genetic similarities with other viruses from wild birds in central Asia, suggesting their potential role in the genesis of A(H5N8). PMID:28609260

  9. How the Science versus Religion Debate Has Missed the Point of Genesis 1 and 2: Jacques Ellul (1912-1994)

    ERIC Educational Resources Information Center

    Vanderburg, Willem H.

    2010-01-01

    From a social and historical perspective, the conflict between science and religion regarding the opening chapters of Genesis in the Jewish and Christian Bibles may have more to do with uncritically reading these texts through our "cultural glasses" than with what these texts actually say. Within the context of his work, Jacques Ellul read these…

  10. Houses and Sheds in Australia: An Exploration of the Genesis and Growth of Neighbourhood Houses and Men's Sheds in Community Settings

    ERIC Educational Resources Information Center

    Golding, Barry; Kimberley, Helen; Foley, Annette; Brown, Mike

    2008-01-01

    This article reviews research into the genesis and spread of both neighbourhood houses and learning centres in Victoria and community-based men's sheds in Australia to identify some similarities and differences. Our article asks questions about the gendered communities of practice that underpin houses for women on the one hand, and sheds for men…

  11. Corporate Information Management: A Case Study

    DTIC Science & Technology

    1991-03-01

    SUBJECT TERMS ( FIELD GROUP SUB-GROUP ICorporate Information Management (CIM), Case study, Strategic level decision making, Department Of Defense. 19...ABSTRACT ( This thesis documents in a case format the events, environment and decisions in the genesis and evolution of the Department of Defense’s...case format the events, environment and decisions in the genesis and evolution of the Department of Defense’s Corporate Information Management

  12. Relationship between the intraseasonal IPCO and tropical cyclogenesis over the Indo-western North Pacific during summertime

    NASA Astrophysics Data System (ADS)

    Wang, Qiuyun; Li, Jianping; Li, Yanjie; Zhang, Jingwen

    2017-04-01

    The influence of the intraseasonal Indo-western Pacific convection oscillation (IPCO) on the tropical cyclone (TC) genesis location and frequency over the Indo-western North Pacific during the summertime (MaytOctober) is explored in this paper. Observational analysis shows that the impacts of the intraseasonal IPCO on TCs over the Indo-western North Pacific features in evident "locational phase lock of TC genesis" and distinct differences in TC frequency. In term of the WNP, when the intraseasonal IPCO is positive phase, there tends to be much more TCs, especially in the South China Sea (SCS), and more TCs generate in the west of the WNP and lower latitude (around 5°-20°N); vice versa. At the positive intraseasonal IPCO phase, the atmosphere gains heat through both sea-air interaction and the latent heat release of cumulus convective condensation, and the anomalous cyclonic circulation weakens the western Pacific subtropical high (WPSH), these conditions do favor the TC genesis. Moreover, the shrinking WPSH, the enhanced heat transfer from sea to air at the lower latitude as well as the westward shifts of heating center and anomalous cyclonic circulation lock TC genesis locations in the west of the WNP and lower latitude. The opposite situation occurs at negative phase. As for the North Indian Ocean (NIO), the TC genesis locations at the positive intraseasonal IPCO phase mainly situate in 13°-20°N and distribute closer to Indian Peninsula, particularly in the Arabian Sea (ARB), in contrast, the spatial distribution is more dispersed at the negative intraseasonal IPCO phase. However, the total TC frequencies at two intraseasonal IPCO phases are similar. These features come largely from the differences in the area featuring conditions between the northern and southern regions of 13°N in the NIO: at the positive intraseasonal IPCO phase, to the northern region of 13°N, the environmental conditions are similar to the case of the WNP except without the WPSH control, and the reversed situations are observed over the southern region of 13°N, which lead to northward shift of TC genesis location. The negative phase reflects an opposite situation.

  13. Polar Ice Sheets Drive Paleohydroclimate Affecting Terrestrial Plant Distribution and CO2 Exchange Potential during the Upper Carboniferous

    NASA Astrophysics Data System (ADS)

    White, J. D.; Poulsen, C. J.; Montanez, I. P.; McElwain, J.; Wilson, J. P.; Hren, M. T.

    2016-12-01

    Variation in atmospheric CO2 concentration and presence or absence of polar ice sheets simulated for 310 mya using the GENESIS model show changes in terrestrial temperature, precipitation, and potential evapotranspiration at mid and lower latitudes. Classifying the data into Holdridge life zones for simulations with 280, 560, and 1120 ppm CO2, in the presence of a southern Gondwanan ice sheet resulted in progressive increase of cool temperate, humid-to-subhumid and tropical subhumid zones. Without the ice sheet, subtropical subhumid to semiarid zones expanded. Simulation results show that approximately 50% of the land area was classified as polar or tundra followed by 35 to 42%, depending on the scenario, classified as sub-tropical semiarid-to-subhumid. Only 5-8% were classified as temperate humid-to-subhumid or tropical humid-to-perhumid. Also, the absence of ice sheets reduced the moister sub-climates, such as within the tropical climate zone. Because different plant assemblages dominated each climate zone, for example cordaitaleans in the subtropical and medullosans and lycophytes in the tropics, physiological differences in these plants may have resulted in unequal CO2 exchange feedbacks to the atmosphere during climate shifts. Previous physiological modeling based on plant foliar traits indicates that late Paleozoic plant species differed in CO2 uptake capacity with highest sensitivity to water availability during periods with low atmospheric CO2 concentration. This implies that vegetation climate feedbacks during this period may have been non-uniform during climate change events. Inference of plant contribution to climate forcing must rely on understanding geographic distribution of affected vegetation, inherent vegetation physiological properties, and antecedent atmospheric CO2 concentrations. Our results indicate that seasonally dry climates prevailed in the low-latitude land area, and that slightly cooler temperatures than today must be considered. This study also shows that mechanistic modeling of paleoclimate should consider the spatial distribution of different plant species, the distribution of water availability for plants within climate zones, and the physiological attributes of species dominating paleolandscapes at specific geologic time periods.

  14. Dynamics of Multistable States during Ongoing and Evoked Cortical Activity

    PubMed Central

    Mazzucato, Luca

    2015-01-01

    Single-trial analyses of ensemble activity in alert animals demonstrate that cortical circuits dynamics evolve through temporal sequences of metastable states. Metastability has been studied for its potential role in sensory coding, memory, and decision-making. Yet, very little is known about the network mechanisms responsible for its genesis. It is often assumed that the onset of state sequences is triggered by an external stimulus. Here we show that state sequences can be observed also in the absence of overt sensory stimulation. Analysis of multielectrode recordings from the gustatory cortex of alert rats revealed ongoing sequences of states, where single neurons spontaneously attain several firing rates across different states. This single-neuron multistability represents a challenge to existing spiking network models, where typically each neuron is at most bistable. We present a recurrent spiking network model that accounts for both the spontaneous generation of state sequences and the multistability in single-neuron firing rates. Each state results from the activation of neural clusters with potentiated intracluster connections, with the firing rate in each cluster depending on the number of active clusters. Simulations show that the model's ensemble activity hops among the different states, reproducing the ongoing dynamics observed in the data. When probed with external stimuli, the model predicts the quenching of single-neuron multistability into bistability and the reduction of trial-by-trial variability. Both predictions were confirmed in the data. Together, these results provide a theoretical framework that captures both ongoing and evoked network dynamics in a single mechanistic model. PMID:26019337

  15. Multiscale Processes of Hurricane Sandy (2012) as Revealed by the CAMVis-MAP

    NASA Astrophysics Data System (ADS)

    Shen, B.; Li, J. F.; Cheung, S.

    2013-12-01

    In late October 2012, Storm Sandy made landfall near Brigantine, New Jersey, devastating surrounding areas and causing tremendous economic loss and hundreds of fatalities (Blake et al., 2013). An estimated damage of $50 billion made Sandy become the second costliest tropical cyclone (TC) in US history, surpassed only by Hurricane Katrina (2005). Central questions to be addressed include (1) to what extent the lead time of severe storm prediction such as Sandy can be extended (e.g., Emanuel 2012); and (2) whether and how advanced global model, supercomputing technology and numerical algorithm can help effectively illustrate the complicated physical processes that are associated with the evolution of the storms. In this study, the predictability of Sandy is addressed with a focus on short-term (or extended-range) genesis prediction as the first step toward the goal of understanding the relationship between extreme events, such as Sandy, and the current climate. The newly deployed Coupled Advanced global mesoscale Modeling (GMM) and concurrent Visualization (CAMVis) system is used for this study. We will show remarkable simulations of Hurricane Sandy with the GMM, including realistic 7-day track and intensity forecast and genesis predictions with a lead time of up to 6 days (e.g., Shen et al., 2013, GRL, submitted). We then discuss the enabling role of the high-resolution 4-D (time-X-Y-Z) visualizations in illustrating TC's transient dynamics and its interaction with tropical waves. In addition, we have finished the parallel implementation of the ensemble empirical mode decomposition (PEEMD, Cheung et al., 2013, AGU13, submitted) method that will be soon integrated into the multiscale analysis package (MAP) for the analysis of tropical weather systems such as TCs and tropical waves. While the original EEMD has previously shown superior performance in decomposition of nonlinear (local) and non-stationary data into different intrinsic modes which stay within the natural filter period windows, the PEEMD achieves a speedup of over 100 times as compared to the original EEMD. The advanced GMM, 4D visualizations and PEEMD method are being used to examine the multiscale processes of Sandy and its environmental flows that may contribute to the extended lead-time predictability of Hurricane Sandy. Figure 1: Evolution of Hurricane Sandy (2012) as revealed by the advanced visualization.

  16. Interdecadal variation of tropical cyclone genesis and its relationship to the convective activities over the central Pacific

    NASA Astrophysics Data System (ADS)

    Huangfu, Jingliang; Huang, Ronghui; Chen, Wen

    2018-02-01

    Using the outgoing longwave radiation (OLR) data from the National Oceanic and Atmospheric Administration archives, this paper analyzes the interdecadal variation of convective activities over the central Pacific (CP) from July to October of 1979-2013 and its impact on tropical cyclone (TC) genesis in the western North Pacific (WNP). Concurrent with the interdecadal decrease of TC genesis, the tropical convection underwent a significant interdecadal change in the late 1990s. Overall, the first leading empirical orthogonal function mode of the tropical OLR during July-October turned from a zonal dipole pattern during 1979-1997 to a tripole pattern during 1998-2013. Concomitant to this change, the boreal part of the Walker circulation shrank westward, with its downdraft branch located over the CP. The downward motion anomalies over the CP increased after the late 1990s, as did the trade easterlies. Consistent with the CP convective activity anomalies, the negative low-level relative vorticity anomalies and upper-level divergence anomalies, positive vertical wind shear anomalies and anomalous abundant water vapor can be observed over the southeastern part of the WNP. Additionally, the tropical depression (TD)-type waves associated with the CP convective activities are significantly different before and after the late 1990s. Before the late 1990s, the off-equatorial TD-type waves could be distinctly observed, with clear transitions located along the WNP monsoon trough. However, these transitions were vague after the late 1990s. Therefore, the convective activities over the CP may have played an important role in affecting the interdecadal change of TC genesis by affecting the genesis of TD-type waves.

  17. Sand waves in environmental flows: Insights gained by coupling large-eddy simulation with morphodynamics

    NASA Astrophysics Data System (ADS)

    Sotiropoulos, Fotis; Khosronejad, Ali

    2016-02-01

    Sand waves arise in subaqueous and Aeolian environments as the result of the complex interaction between turbulent flows and mobile sand beds. They occur across a wide range of spatial scales, evolve at temporal scales much slower than the integral scale of the transporting turbulent flow, dominate river morphodynamics, undermine streambank stability and infrastructure during flooding, and sculpt terrestrial and extraterrestrial landscapes. In this paper, we present the vision for our work over the last ten years, which has sought to develop computational tools capable of simulating the coupled interactions of sand waves with turbulence across the broad range of relevant scales: from small-scale ripples in laboratory flumes to mega-dunes in large rivers. We review the computational advances that have enabled us to simulate the genesis and long-term evolution of arbitrarily large and complex sand dunes in turbulent flows using large-eddy simulation and summarize numerous novel physical insights derived from our simulations. Our findings explain the role of turbulent sweeps in the near-bed region as the primary mechanism for destabilizing the sand bed, show that the seeds of the emergent structure in dune fields lie in the heterogeneity of the turbulence and bed shear stress fluctuations over the initially flatbed, and elucidate how large dunes at equilibrium give rise to energetic coherent structures and modify the spectra of turbulence. We also discuss future challenges and our vision for advancing a data-driven simulation-based engineering science approach for site-specific simulations of river flooding.

  18. EnKF OSSE Experiments Assessing the Impact of HIRAD Wind Speed and HIWRAP Radial Velocity Data on Analysis of Hurricane Karl (2010)

    NASA Technical Reports Server (NTRS)

    Albers, Cerese; Sippel, Jason A.; Braun, Scott A.; Miller, Timothy

    2012-01-01

    Previous studies (e.g., Zhang et al. 2009, Weng et al. 2011) have shown that radial velocity data from airborne and ground-based radars can be assimilated into ensemble Kalman filter (EnKF) systems to produce accurate analyses of tropical cyclone vortices, which can reduce forecast intensity error. Recently, wind speed data from SFMR technology has also been assimilated into the same types of systems and has been shown to improve the forecast intensity of mature tropical cyclones. Two instruments that measure these properties were present during the NASA Genesis and Rapid Intensification Processes (GRIP) field experiment in 2010 which sampled Hurricane Karl, and will next be co-located on the same aircraft for the subsequent NASA HS3 experiment. The High Altitude Wind and Rain Profiling Radar (HIWRAP) is a conically scanning Doppler radar mounted upon NASAs Global Hawk unmanned aerial vehicle, and the usefulness of its radial velocity data for assimilation has not been previously examined. Since the radar scans from above with a fairly large fixed elevation angle, it observes a large component of the vertical wind, which could degrade EnKF analyses compared to analyses with data taken from lesser elevation angles. The NASA Hurricane Imaging Radiometer (HIRAD) is a passive microwave radiometer similar to SFMR, and measures emissivity and retrieves hurricane surface wind speeds and rain rates over a much wider swath. Thus, this study examines the impact of assimilating simulated HIWRAP radial velocity data into an EnKF system, simulated HIRAD wind speed, and HIWRAP+HIRAD with the Weather Research and Forecasting (WRF) model and compares the results to no data assimilation and also to the Truth from which the data was simulated for both instruments.

  19. [Measurements of blood velocities using duplex sonography in carotid artery stents: analysis of reliability in an in-vitro model and computational fluid dynamics (CFD)].

    PubMed

    Schönwald, U G; Jorczyk, U; Kipfmüller, B

    2011-01-01

    Stents are commonly used for the treatment of occlusive artery diseases in carotid arteries. Today, there is a controversial discussion as to whether duplex sonography (DS) displays blood velocities (BV) that are too high in stented areas. The goal of this study was to evaluate the effect of stenting on DS with respect to BV in artificial carotid arteries. The results of computational fluid dynamics (CFD) were also used for the comparison. To analyze BV using DS, a phantom with a constant flow (70 cm/s) was created. Three different types of stents for carotid arteries were selected. The phantom fluid consisted of 67 % water and 33 % glycerol. All BV measurements were carried out on the last third of the stents. Furthermore, all test runs were simulated using CFD. All measurements were statistically analyzed. DS-derived BV values increased significantly after the placement of the Palmaz Genesis stent (77.6 ± 4.92 cm/sec, p = 0.03). A higher increase in BV values was registered when using the Precise RX stent (80.1 ± 2.01 cm/sec, p < 0.0001). The Strecker Tantalum stent (85.9 ± 1.95 cm/sec, p < 0.0001) generated the highest BV values. CFD simulations showed similar results. Stents have a significant impact on BV, but no effect on DS. The main factor of the blood flow acceleration is the material thickness of the stents. Therefore, different stents need different velocity criteria. Furthermore, the results of computational fluid dynamics prove that CFD can be used to simulate BV in stented silicone tubes. © Georg Thieme Verlag KG Stuttgart · New York.

  20. A strategy for assessing potential future changes in climate, hydrology, and vegetation in the Western United States

    USGS Publications Warehouse

    Thompson, Robert Stephen; Hostetler, Steven W.; Bartlein, Patrick J.; Anderson, Katherine H.

    1998-01-01

    Historical and geological data indicate that significant changes can occur in the Earth's climate on time scales ranging from years to millennia. In addition to natural climatic change, climatic changes may occur in the near future due to increased concentrations of carbon dioxide and other trace gases in the atmosphere that are the result of human activities. International research efforts using atmospheric general circulation models (AGCM's) to assess potential climatic conditions under atmospheric carbon dioxide concentrations of twice the pre-industrial level (a '2 X CO2' atmosphere) conclude that climate would warm on a global basis. However, it is difficult to assess how the projected warmer climatic conditions would be distributed on a regional scale and what the effects of such warming would be on the landscape, especially for temperate mountainous regions such as the Western United States. In this report, we present a strategy to assess the regional sensitivity to global climatic change. The strategy makes use of a hierarchy of models ranging from an AGCM, to a regional climate model, to landscape-scale process models of hydrology and vegetation. A 2 X CO2 global climate simulation conducted with the National Center for Atmospheric Research (NCAR) GENESIS AGCM on a grid of approximately 4.5o of latitude by 7.5o of longitude was used to drive the NCAR regional climate model (RegCM) over the Western United States on a grid of 60 km by 60 km. The output from the RegCM is used directly (for hydrologic models) or interpolated onto a 15-km grid (for vegetation models) to quantify possible future environmental conditions on a spatial scale relevant to policy makers and land managers.

  1. Initial Subdivision of Genesis Early Science Polished Aluminum Collector

    NASA Technical Reports Server (NTRS)

    Allton, J. H.; Stansbery, E. K.; McNamara, K. M.; Meshik, A.; See, T. H.; Bastien, R.

    2005-01-01

    A large surface, about 245 square centimeters, of highly polished aluminum 6061 T6 alloy was attached to the science canister thermal panel for the purpose of collecting solar wind noble gases. The analysis of this collector will be part of the Genesis Early Science results. The pre-launch configuration of the collector is shown. The collector sustained some damage during the recovery impact in Utah, September 8, 2004.

  2. Education in the Knowledge Society: Genesis of Concept and Reality

    ERIC Educational Resources Information Center

    Karpov, Alexander O.

    2016-01-01

    The aim of the article is to define the content of theoretical ideas about education in the knowledge society in terms of the birth of its social reality. It is shown that the genesis of the concept of education in the knowledge society goes back to the period of 1950-1960s and is due to the emergence of new qualities of an industrial worker that…

  3. David Florida Laboratory Thermal Vacuum Data Processing System

    NASA Technical Reports Server (NTRS)

    Choueiry, Elie

    1994-01-01

    During 1991, the Space Simulation Facility conducted a survey to assess the requirements and analyze the merits for purchasing a new thermal vacuum data processing system for its facilities. A new, integrated, cost effective PC-based system was purchased which uses commercial off-the-shelf software for operation and control. This system can be easily reconfigured and allows its users to access a local area network. In addition, it provides superior performance compared to that of the former system which used an outdated mini-computer and peripheral hardware. This paper provides essential background on the old data processing system's features, capabilities, and the performance criteria that drove the genesis of its successor. This paper concludes with a detailed discussion of the thermal vacuum data processing system's components, features, and its important role in supporting our space-simulation environment and our capabilities for spacecraft testing. The new system was tested during the ANIK E spacecraft test, and was fully operational in November 1991.

  4. Diagnosis of seasonal variations of tropical cyclogenesis over the South China Sea using a genesis potential index

    NASA Astrophysics Data System (ADS)

    Wang, Lei; Pan, Xiumei

    2012-09-01

    This study examines the seasonal variations of tropical cyclogenesis over the South China Sea (SCS) using a genesis potential (GP) index developed by Emanuel and Nolan. How different environmental factors (including low-level vorticity, mid-level relative humidity, vertical wind shear, and potential intensity) contribute to these variations is investigated. Composite anomalies of the GP index are produced for the summer and winter monsoons separately. These composites replicate the observed seasonal variations of the observed frequency and location of tropical cyclogenesis over the SCS. The degree of contribution by each factor in different regions is determined quantitatively by producing composites of modified indices in which only one of the contributing factors varies, with the others set to climatology. Over the northern SCS, potential intensity makes the largest contributions to the seasonal variations in tropical cyclogenesis. Over the southern SCS, the low-level relative vorticity plays the primary role in the seasonal modulation of tropical cyclone (TC) genesis frequency, and the vertical wind shear plays the secondary role. Thermodynamic factors play more important roles for the seasonal variations in tropical cyclogenesis over the northern SCS, while dynamic factors are more important in the seasonal modulation of TC genesis frequency over the southern SCS.

  5. Genesis Silicon Carbide Concentrator Target 60003 Preliminary Ellipsometry Mapping Results

    NASA Technical Reports Server (NTRS)

    Calaway, M. J.; Rodriquez, M. C.; Stansbery, E. K.

    2007-01-01

    The Genesis concentrator was custom designed to focus solar wind ions primarily for terrestrial isotopic analysis of O-17/O-16 and O-18/O-16 to +/-1%, N-15/N-14 to +/-1%, and secondarily to conduct elemental and isotopic analysis of Li, Be, and B. The circular 6.2 cm diameter concentrator target holder was comprised of four quadrants of highly pure semiconductor materials that included one amorphous diamond-like carbon, one C-13 diamond, and two silicon carbide (SiC). The amorphous diamond-like carbon quadrant was fractured upon impact at Utah Test and Training Range (UTTR), but the remaining three quadrants survived fully intact and all four quadrants hold an important collection of solar wind. The quadrants were removed from the target holder at NASA Johnso n Space Center Genesis Curation Laboratory in April 2005, and have been housed in stainless steel containers under continual nitrogen purge since time of disintegration. In preparation for allocation of a silicon carbide target for oxygen isotope analyses at UCLA, the two SiC targets were photographed for preliminary inspection of macro particle contamination from the hard non-nominal landing as well as characterized by spectroscopic ellipsometry to evaluate thin film contamination. This report is focused on Genesis SiC target sample number 60003.

  6. Geomorphic clues to the Martian volatile inventory. 1: Flow ejecta blankets

    NASA Technical Reports Server (NTRS)

    Pieri, D.; Baloga, S.; Norris, M.

    1984-01-01

    There are classes of landforms whose presence on Mars is strongly suggestive, if not confirmatory, of the participation of volatiles, presumably water, in its geomorphic development: (1) valley networks, (2) outflow channels, (3) landslides, and (4) flow-ejecta blankets. The first two may represent landforms generated by the movement of volatiles from sources, while the latter two probably represent the dissipation of energy generated by forcing inputs (e.g., kinetic energy and gravity) modulated by volatiles. In many areas on Mars, all four processes have acted on the same lithologic materials and were influenced by the composition of those units, and possibility by the climatic regime at the time of their formation. One of the approaches discussed to this specific problem of landform genesis, and to the general problem of the present and past states of martian volatiles, is to attempt to constrain the distribution, amount, and history of available volatiles by using possible evidence of volatile participation expressed in the morphology of other related landforms (e.g., flow-ejecta blankets and landslides) coupled with physical models for landform genesis.

  7. Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain.

    PubMed

    Voronova, Anastassia; Yuzwa, Scott A; Wang, Beatrix S; Zahr, Siraj; Syal, Charvi; Wang, Jing; Kaplan, David R; Miller, Freda D

    2017-05-03

    During development, newborn interneurons migrate throughout the embryonic brain. Here, we provide evidence that these interneurons act in a paracrine fashion to regulate developmental oligodendrocyte formation. Specifically, we show that medial ganglionic eminence (MGE) interneurons secrete factors that promote genesis of oligodendrocytes from glially biased cortical precursors in culture. Moreover, when MGE interneurons are genetically ablated in vivo prior to their migration, this causes a deficit in cortical oligodendrogenesis. Modeling of the interneuron-precursor paracrine interaction using transcriptome data identifies the cytokine fractalkine as responsible for the pro-oligodendrocyte effect in culture. This paracrine interaction is important in vivo, since knockdown of the fractalkine receptor CX3CR1 in embryonic cortical precursors, or constitutive knockout of CX3CR1, causes decreased numbers of oligodendrocyte progenitor cells (OPCs) and oligodendrocytes in the postnatal cortex. Thus, in addition to their role in regulating neuronal excitability, interneurons act in a paracrine fashion to promote the developmental genesis of oligodendrocytes. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Geomorphic clues to the Martian volatile inventory. 1: Flow ejecta blankets

    NASA Astrophysics Data System (ADS)

    Pieri, D.; Baloga, S.; Norris, M.

    1984-04-01

    There are classes of landforms whose presence on Mars is strongly suggestive, if not confirmatory, of the participation of volatiles, presumably water, in its geomorphic development: (1) valley networks, (2) outflow channels, (3) landslides, and (4) flow-ejecta blankets. The first two may represent landforms generated by the movement of volatiles from sources, while the latter two probably represent the dissipation of energy generated by forcing inputs (e.g., kinetic energy and gravity) modulated by volatiles. In many areas on Mars, all four processes have acted on the same lithologic materials and were influenced by the composition of those units, and possibility by the climatic regime at the time of their formation. One of the approaches discussed to this specific problem of landform genesis, and to the general problem of the present and past states of martian volatiles, is to attempt to constrain the distribution, amount, and history of available volatiles by using possible evidence of volatile participation expressed in the morphology of other related landforms (e.g., flow-ejecta blankets and landslides) coupled with physical models for landform genesis.

  9. Global peatland initiation driven by regionally asynchronous warming.

    PubMed

    Morris, Paul J; Swindles, Graeme T; Valdes, Paul J; Ivanovic, Ruza F; Gregoire, Lauren J; Smith, Mark W; Tarasov, Lev; Haywood, Alan M; Bacon, Karen L

    2018-05-08

    Widespread establishment of peatlands since the Last Glacial Maximum represents the activation of a globally important carbon sink, but the drivers of peat initiation are unclear. The role of climate in peat initiation is particularly poorly understood. We used a general circulation model to simulate local changes in climate during the initiation of 1,097 peatlands around the world. We find that peat initiation in deglaciated landscapes in both hemispheres was driven primarily by warming growing seasons, likely through enhanced plant productivity, rather than by any increase in effective precipitation. In Western Siberia, which remained ice-free throughout the last glacial period, the initiation of the world's largest peatland complex was globally unique in that it was triggered by an increase in effective precipitation that inhibited soil respiration and allowed wetland plant communities to establish. Peat initiation in the tropics was only weakly related to climate change, and appears to have been driven primarily by nonclimatic mechanisms such as waterlogging due to tectonic subsidence. Our findings shed light on the genesis and Holocene climate space of one of the world's most carbon-dense ecosystem types, with implications for understanding trajectories of ecological change under changing future climates.

  10. Unmixing the Galactic halo with RR Lyrae tagging

    NASA Astrophysics Data System (ADS)

    Belokurov, V.; Deason, A. J.; Koposov, S. E.; Catelan, M.; Erkal, D.; Drake, A. J.; Evans, N. W.

    2018-06-01

    We show that tagging RR Lyrae stars according to their location in the period-amplitude diagram can be used to shed light on the genesis of the Galactic stellar halo. The mixture of RR Lyrae of ab type, separated into classes along the lines suggested by Oosterhoff, displays a strong and coherent evolution with Galactocentric radius. The change in the RR Lyrae composition appears to coincide with the break in the halo's radial density profile at ˜25 kpc. Using simple models of the stellar halo, we establish that at least three different types of accretion events are necessary to explain the observed RRab behaviour. Given that there exists a correlation between the RRab class fraction and the total stellar content of a dwarf satellite, we hypothesize that the field halo RRab composition is controlled by the mass of the progenitor contributing the bulk of the stellar debris at the given radius. This idea is tested against a suite of cosmological zoom-in simulations of Milky Way-like stellar halo formation. Finally, we study some of the most prominent stellar streams in the Milky Way halo and demonstrate that their RRab class fractions follow the trends established previously.

  11. Tropical Cyclone Genesis and Sudden Changes of Track and Intensity in the Western Pacific

    DTIC Science & Technology

    2008-09-30

    North Atlantic . (Published in 2008) Our work on the effect of internally generated inner-core asymmetries on tropical cyclone potential intensity has...of the atmospheric circulation in TC basins to the global warming is more critical than increasing SST to understanding the impacts of global warming...Japan and its adjacent seas is studied with WRF model. The results suggest that the northward moisture transport through the outer cyclonic circulation

  12. Role and Mechanism of Structural Variation in Progression of Breast Cancer

    DTIC Science & Technology

    2012-09-01

    models  of  CGR  genesis,  and  strongly  argue...numbers  of  tandem   duplications,  and   GBM  samples  showing  numerous  large-­‐scale  rearrangements.  We  also...higher   incidence  in   GBM  (38.9%)  relative  to  the  other  tumor  types  (8.7%).   This  definitively  shows

  13. Ensemble Prediction of Tropical Cyclone Genesis

    DTIC Science & Technology

    2017-02-23

    future changes in tropical cyclone (TC) activity around the Hawaiian Islands are investigated using the state-of-the-art climate models1–3. We find that...future warmer climate . This is in contrast to the NA, where BDI increases for all dynamic variables investigated while it shows little change for...Li, and A. Kitoh, 2013: Projected future increase in tropical cyclones near Hawaii. Nature Climate Change , 3, 749-754, doi:10.1038/nclimate1890

  14. Experimental hydrocephalus following mechanical increment of intraventricular pulse pressure.

    PubMed

    Di Rocco, C; Pettorossi, V E; Caldarelli, M; Mancinelli, R; Velardi, F

    1977-11-15

    Experimental hydrocephalus has been induced in lambs by artificial increase of the amplitude of intraventricular cerebrospinal fluid (CSF) oscillations related to arterial pulsations, without concomitant changes of the mean CSF-pressure. The characteristics of this hydrocephalus demonstrate that the intraventricular CSF-pulsations can play a role in the genesis of ventricular dilation. Such a method may be used to produce an original model of hydrocephalus independent of changes of CSF-circulation or absorption.

  15. Item Selection, Evaluation, and Simple Structure in Personality Data

    PubMed Central

    Pettersson, Erik; Turkheimer, Eric

    2010-01-01

    We report an investigation of the genesis and interpretation of simple structure in personality data using two very different self-reported data sets. The first consists of a set of relatively unselected lexical descriptors, whereas the second is based on responses to a carefully constructed instrument. In both data sets, we explore the degree of simple structure by comparing factor solutions to solutions from simulated data constructed to have either strong or weak simple structure. The analysis demonstrates that there is little evidence of simple structure in the unselected items, and a moderate degree among the selected items. In both instruments, however, much of the simple structure that could be observed originated in a strong dimension of positive vs. negative evaluation. PMID:20694168

  16. Selected Aspects of Soil Science History in the USA - Prehistory to the 1970s

    NASA Astrophysics Data System (ADS)

    Brevik, Eric C.; Fenton, Thomas E.; Homburg, Jeffrey A.

    2017-04-01

    Interest in understanding America's soils originated in prehistory with Native Americans. Following European settlement, notable individuals such as Thomas Jefferson and Lewis and Clark made observations of soil resources. Moving into the 1800s, state geological surveys became involved in soil work and E.W. Hilgard started to formulate ideas similar to those that would eventually lead to V.V. Dokuchaev being recognized as the father of modern soil science. However, Hilgard's advanced ideas on soil genesis were not accepted by the wider American soil science community at the time. Moving into the 1900s, the National Cooperative Soil Survey, the first nationally organized detailed soil survey in the world, was founded under the direction of M. Whitney. Initial soil classification ideas were heavily based in geology, but over time Russian ideas of soil genesis and classification moved into the American soil science community, mainly due to the influence of C.F. Marbut. Early American efforts in scientific study of soil erosion and soil fertility were also initiated in the 1910s and university programs to educate soil scientists started. Soil erosion studies took on high priority in the 1930s as the USA was impacted by the Dust Bowl. Soil Taxonomy, one of the most widely utilized soil classification systems in the world, was developed from the 1950s through the 1970s under the guidance of G.D. Smith and with administrative support from C.E. Kellogg. American soil scientists, such as H. Jenny, R.W. Simonson, D.L. Johnson, and D. Watson-Stegner, developed influential models of soil genesis during the 20th Century, and the use of soil information expanded beyond agriculture to include issues such as land-use planning, soil geomorphology, and interactions between soils and human health.

  17. The role of mid-level vortex in the intensification and weakening of tropical cyclones

    NASA Astrophysics Data System (ADS)

    Kutty, Govindan; Gohil, Kanishk

    2017-10-01

    The present study examines the dynamics of mid-tropospheric vortex during cyclogenesis and quantifies the importance of such vortex developments in the intensification of tropical cyclone. The genesis of tropical cyclones are investigated based on two most widely accepted theories that explain the mechanism of cyclone formation namely `top-down' and `bottom-up' dynamics. The Weather Research and Forecast model is employed to generate high resolution dataset required for analysis. The development of the mid-level vortex was analyzed with regard to the evolution of potential vorticity (PV), relative vorticity (RV) and vertical wind shear. Two tropical cyclones which include the developing cyclone, Hudhud and the non-developing cyclone, Helen are considered. Further, Hudhud and Helen, is compared to a deep depression formed over Bay of Bengal to highlight the significance of the mid-level vortex in the genesis of a tropical cyclone. Major results obtained are as follows: stronger positive PV anomalies are noticed over upper and lower levels of troposphere near the storm center for Hudhud as compared to Helen and the depression; Constructive interference in upper and lower level positive PV anomaly maxima resulted in the intensification of Hudhud. For Hudhud, the evolution of RV follows `top-down' dynamics, in which the growth starts from the middle troposphere and then progresses downwards. As for Helen, RV growth seems to follow `bottom-up' mechanism initiating growth from the lower troposphere. Though, the growth of RV for the depression initiates from mid-troposphere, rapid dissipation of mid-level vortex destabilizes the system. It is found that the formation mid-level vortex in the genesis phase is significantly important for the intensification of the storm.

  18. Adolescent cocaine exposure enhances goal-tracking behavior and impairs hippocampal cell genesis selectively in adult bred low-responder rats

    PubMed Central

    García-Fuster, M. Julia; Parsegian, Aram; Watson, Stanley J.; Akil, Huda; Flagel, Shelly B.

    2018-01-01

    Rationale Environmental challenges during adolescence, such as drug exposure, can cause enduring behavioral and molecular changes that contribute to life-long maladaptive behaviors, including addiction. Selectively bred high-responder (bHR) and low-responder (bLR) rats represent a unique model for assessing the long-term impact of adolescent environmental manipulations, as they inherently differ on a number of addiction-related traits. bHR rats are considered “addiction-prone”, whereas bLR rats are “addiction-resilient”, at least under baseline conditions. Moreover, relative to bLRs, bHR rats are more likely to attribute incentive motivational value to reward cues, or to “sign-track”. Objectives We utilized bHR and bLR rats to determine whether adolescent cocaine exposure can alter their inborn behavioral and neurobiological profiles, with a specific focus on Pavlovian conditioned approach behavior (i.e. sign- vs. goal-tracking) and hippocampal neurogenesis. Methods bHR and bLR rats were administered cocaine (15 mg/kg) or saline for 7 days during adolescence (postnatal day, PND 33–39) and subsequently tested for Pavlovian conditioned approach behavior in adulthood (PND 62–75), wherein an illuminated lever (conditioned stimulus) was followed by the response-independent delivery of a food pellet (unconditioned stimulus). Behaviors directed towards the lever and the food cup were recorded as sign- and goal-tracking, respectively. Hippocampal cell genesis was evaluated on PND 77 by immunohistochemistry. Results Adolescent cocaine exposure impaired hippocampal cell genesis (proliferation and survival) and enhanced the inherent propensity to goal-track in adult bLR, but not bHR, rats. Conclusions Adolescent cocaine exposure elicits long-lasting changes in stimulus-reward learning and enduring deficits in hippocampal neurogenesis selectively in adult bLR rats. PMID:28210781

  19. 50 Myr of pulsed mafic magmatism in the High Arctic Large Igneous Province

    NASA Astrophysics Data System (ADS)

    Pearson, D. G.; Dockman, D. M.; Heaman, L. M.; Gibson, S. A.; Sarkar, C.

    2017-12-01

    Extensive and voluminous Cretaceous mafic magmatism in the Sverdrup Basin of Arctic Canada forms the circum-Arctic High Arctic Large Igneous Province (HALIP). The small number of published high-precision ages for this LIP indicate its eruption over a considerable timespan raising concerns over whether the HALIP can be strictly defined as a single LIP and questioning the role of a single or multiple plumes in its genesis. Here we present an integrated geochemical and geochronological study to better constrain the timing and cause of mafic magma genesis in the Canadian HALIP. Six new U-Pb and four 40Ar/39Ar ages of mafic lavas and intrusive sheets range from 121 Ma to 78 Ma. The U-Pb ages are the first analyzed from the mafic intrusions of Axel Heiberg and Ellesmere Islands. The new geochronology, combined with other published high-precision ages, reveal a > 50 Myr duration of mafic magmatism in the HALIP defined by three main pulses. Tholeiites dominate the initial 25 Myr of magmatism, transitioning to coeval emplacement of alkali and tholeiitic basalts. Whole-rock Sr-Nd isotope ratios indicate that both magma types are derived from a similar source dominated by convecting mantle. Rare-earth-element inversion models reveal that the alkalic and tholeiitic magmas were generated beneath a bimodal lithospheric `lid' thickness of 65 ± 5 and 45 ± 4 km, respectively. We suggest that the early 128 - 122 Ma tholeiitic event is primarily plume-generated and correlates across the circum-Arctic with the other HALIP tholeiites. Younger HALIP magmatism, with coeval alkalic and tholeiitic magmas erupting over 25 Myr, may be explained by alternating modes of edge-driven mantle convection as the primary control on magma genesis. A distal plume may have intensified magma production by edge-driven convection.

  20. Downregulation of RND3/RhoE in glioblastoma patients promotes tumorigenesis through augmentation of notch transcriptional complex activity.

    PubMed

    Liu, Baohui; Lin, Xi; Yang, Xiangsheng; Dong, Huimin; Yue, Xiaojing; Andrade, Kelsey C; Guo, Zhentao; Yang, Jian; Wu, Liquan; Zhu, Xiaonan; Zhang, Shenqi; Tian, Daofeng; Wang, Junmin; Cai, Qiang; Chen, Qizuan; Mao, Shanping; Chen, Qianxue; Chang, Jiang

    2015-09-01

    Activation of Notch signaling contributes to glioblastoma multiform (GBM) tumorigenesis. However, the molecular mechanism that promotes the Notch signaling augmentation during GBM genesis remains largely unknown. Identification of new factors that regulate Notch signaling is critical for tumor treatment. The expression levels of RND3 and its clinical implication were analyzed in GBM patients. Identification of RND3 as a novel factor in GBM genesis was demonstrated in vitro by cell experiments and in vivo by a GBM xenograft model. We found that RND3 expression was significantly decreased in human glioblastoma. The levels of RND3 expression were inversely correlated with Notch activity, tumor size, and tumor cell proliferation, and positively correlated with patient survival time. We demonstrated that RND3 functioned as an endogenous repressor of the Notch transcriptional complex. RND3 physically interacted with NICD, CSL, and MAML1, the Notch transcriptional complex factors, promoted NICD ubiquitination, and facilitated the degradation of these cofactor proteins. We further revealed that RND3 facilitated the binding of NICD to FBW7, a ubiquitin ligase, and consequently enhanced NICD protein degradation. Therefore, Notch transcriptional activity was inhibited. Forced expression of RND3 repressed Notch signaling, which led to the inhibition of glioblastoma cell proliferation in vitro and tumor growth in the xenograft mice in vivo. Downregulation of RND3, however, enhanced Notch signaling activity, and subsequently promoted glioma cell proliferation. Inhibition of Notch activity abolished RND3 deficiency-mediated GBM cell proliferation. We conclude that downregulation of RND3 is responsible for the enhancement of Notch activity that promotes glioblastoma genesis. © 2015 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

  1. Downregulation of RND3/RhoE in glioblastoma patients promotes tumorigenesis through augmentation of notch transcriptional complex activity

    PubMed Central

    Liu, Baohui; Lin, Xi; Yang, Xiangsheng; Dong, Huimin; Yue, Xiaojing; Andrade, Kelsey C; Guo, Zhentao; Yang, Jian; Wu, Liquan; Zhu, Xiaonan; Zhang, Shenqi; Tian, Daofeng; Wang, Junmin; Cai, Qiang; Chen, Qizuan; Mao, Shanping; Chen, Qianxue; Chang, Jiang

    2015-01-01

    Activation of Notch signaling contributes to glioblastoma multiform (GBM) tumorigenesis. However, the molecular mechanism that promotes the Notch signaling augmentation during GBM genesis remains largely unknown. Identification of new factors that regulate Notch signaling is critical for tumor treatment. The expression levels of RND3 and its clinical implication were analyzed in GBM patients. Identification of RND3 as a novel factor in GBM genesis was demonstrated in vitro by cell experiments and in vivo by a GBM xenograft model. We found that RND3 expression was significantly decreased in human glioblastoma. The levels of RND3 expression were inversely correlated with Notch activity, tumor size, and tumor cell proliferation, and positively correlated with patient survival time. We demonstrated that RND3 functioned as an endogenous repressor of the Notch transcriptional complex. RND3 physically interacted with NICD, CSL, and MAML1, the Notch transcriptional complex factors, promoted NICD ubiquitination, and facilitated the degradation of these cofactor proteins. We further revealed that RND3 facilitated the binding of NICD to FBW7, a ubiquitin ligase, and consequently enhanced NICD protein degradation. Therefore, Notch transcriptional activity was inhibited. Forced expression of RND3 repressed Notch signaling, which led to the inhibition of glioblastoma cell proliferation in vitro and tumor growth in the xenograft mice in vivo. Downregulation of RND3, however, enhanced Notch signaling activity, and subsequently promoted glioma cell proliferation. Inhibition of Notch activity abolished RND3 deficiency-mediated GBM cell proliferation. We conclude that downregulation of RND3 is responsible for the enhancement of Notch activity that promotes glioblastoma genesis. PMID:26108681

  2. Divergent responses of tropical cyclone genesis factors to strong volcanic eruptions at different latitudes

    NASA Astrophysics Data System (ADS)

    Yan, Qing; Zhang, Zhongshi; Wang, Huijun

    2018-03-01

    To understand the behaviors of tropical cyclones (TCs), it is very important to explore how TCs respond to anthropogenic greenhouse gases and natural forcings. Volcanic eruptions are a major natural forcing mechanism because they inject sulphate aerosols into the stratosphere, which modulate the global climate by absorbing and scattering solar radiation. The number of Atlantic hurricanes is thought to be reduced following strong tropical eruptions, but whether the response of TCs varies with the locations of the volcanoes and the different ocean basins remains unknown. Here, we use the Community Earth System Model-Last Millennium Ensemble to investigate the response of the large-scale environmental factors that spawn TCs to strong volcanic eruptions at different latitudes. A composite analysis indicates that tropical and northern hemisphere volcanic eruptions lead to significantly unfavorable conditions for TC genesis over the whole Pacific basin and the North Atlantic during the 3 years post-eruption, relative to the preceding 3 years. Southern hemisphere volcanic eruptions result in obviously unfavorable conditions for TC formation over the southwestern Pacific, but more favorable conditions over the North Atlantic. The mean response over the Indian Ocean is generally muted and insignificant. It should be noted that volcanic eruptions impact on environmental conditions through both the direct effect (i.e. on radiative forcing) and the indirect effect (i.e. on El Niño-Southern Oscillation), which is not differentiated in this study. In addition, the spread of the TC genesis response is considerably large for each category of eruptions over each ocean basin, which is also seen in the observational/proxy-based records. This large spread is attributed to the differences in stratospheric aerosol distributions, initial states and eruption intensities, and makes the short-term forecast of TC activity following the next large eruption challenging.

  3. Detecting Tsunami Genesis and Scales Directly from Coastal GPS Stations

    NASA Astrophysics Data System (ADS)

    Song, Y. Tony

    2013-04-01

    Different from the conventional approach to tsunami warnings that rely on earthquake magnitude estimates, we have found that coastal GPS stations are able to detect continental slope displacements of faulting due to big earthquakes, and that the detected seafloor displacements are able to determine tsunami source energy and scales instantaneously. This method has successfully replicated several historical tsunamis caused by the 2004 Sumatra earthquake, the 2005 Nias earthquake, the 2010 Chilean earthquake, and the 2011 Tohoku-Oki earthquake, respectively, and has been compared favorably with the conventional seismic solutions that usually take hours or days to get through inverting seismographs (reference listed). Because many coastal GPS stations are already in operation for measuring ground motions in real time as often as once every few seconds, this study suggests a practical way of identifying tsunamigenic earthquakes for early warnings and reducing false alarms. Reference Song, Y. T., 2007: Detecting tsunami genesis and scales directly from coastal GPS stations, Geophys. Res. Lett., 34, L19602, doi:10.1029/2007GL031681. Song, Y. T., L.-L. Fu, V. Zlotnicki, C. Ji, V. Hjorleifsdottir, C.K. Shum, and Y. Yi, 2008: The role of horizontal impulses of the faulting continental slope in generating the 26 December 2004 Tsunami, Ocean Modelling, doi:10.1016/j.ocemod.2007.10.007. Song, Y. T. and S.C. Han, 2011: Satellite observations defying the long-held tsunami genesis theory, D.L. Tang (ed.), Remote Sensing of the Changing Oceans, DOI 10.1007/978-3-642-16541-2, Springer-Verlag Berlin Heidelberg. Song, Y. T., I. Fukumori, C. K. Shum, and Y. Yi, 2012: Merging tsunamis of the 2011 Tohoku-Oki earthquake detected over the open ocean, Geophys. Res. Lett., doi:10.1029/2011GL050767 (Nature Highlights, March 8, 2012).

  4. Quasi-Equilibrium States in the Tropics Simulated by a Cloud-Resolving Model. Part 1; Specific Features and Budget Analysis

    NASA Technical Reports Server (NTRS)

    Shie, C.-L.; Tao, W.-K.; Simpson, J.; Sui, C.-H.; Starr, David OC. (Technical Monitor)

    2001-01-01

    A series of long-term integrations using the two-dimensional Goddard Cumulus Ensemble (GCE) model were performed by altering imposed environmental components to produce various quasi-equilibrium thermodynamic states. Model results show that the genesis of a warm/wet quasi-equilibrium state is mainly due to either strong vertical wind shear (from nudging) or large surface fluxes (from strong surface winds), while a cold/dry quasi-equilibrium state is attributed to a remarkably weakened mixed-wind shear (from vertical mixing due to deep convection) along with weak surface winds. In general, latent heat flux and net large-scale temperature forcing, the two dominant physical processes, dominate in the beginning stage of the simulated convective systems, then considerably weaken in the final stage, which leads to quasi-equilibrium states. A higher thermodynamic regime is found to produce a larger rainfall amount, as convective clouds are the leading source of rainfall over stratiform clouds even though the former occupy much less area. Moreover, convective clouds are more likely to occur in the presence of strong surface winds (latent heat flux), while stratiform clouds (especially the well-organized type) are favored in conditions with strong wind shear (large-scale forcing). The convective systems, which consist of distinct cloud types due to the variation in horizontal winds, are also found to propagate differently. Accordingly, convective systems with mixed-wind shear generally propagate in the direction of shear, while the system with strong (multidirectional) wind shear propagates in a more complex way. Based on the results from the temperature (Q1) and moisture (Q2) budgets, cloud-scale eddies are found to act as a hydrodynamic 'vehicle' that cascades the heat and moisture vertically. Several other specific features such as atmospheric stability, CAPE, and mass fluxes are also investigated and found to be significantly different between diverse quasi-equilibrium states. Detailed comparisons between the various states are presented.

  5. A Genesis breakup and burnup analysis in off-nominal Earth return and atmospheric entry

    NASA Technical Reports Server (NTRS)

    Salama, Ahmed; Ling, Lisa; McRonald, Angus

    2005-01-01

    The Genesis project conducted a detailed breakup/burnup analysis before the Earth return to determine if any spacecraft component could survive and reach the ground intact in case of an off-nominal entry. In addition, an independent JPL team was chartered with the responsibility of analyzing several definitive breakup scenarios to verify the official project analysis. This paper presents the analysis and results of this independent team.

  6. The instrumental genesis process in future primary teachers using Dynamic Geometry Software

    NASA Astrophysics Data System (ADS)

    Ruiz-López, Natalia

    2018-05-01

    This paper, which describes a study undertaken with pairs of future primary teachers using GeoGebra software to solve geometry problems, includes a brief literature review, the theoretical framework and methodology used. An analysis of the instrumental genesis process for a pair participating in the case study is also provided. This analysis addresses the techniques and types of dragging used, the obstacles to learning encountered, a description of the interaction between the pair and their interaction with the teacher, and the type of language used. Based on this analysis, possibilities and limitations of the instrumental genesis process are identified for the development of geometric competencies such as conjecture creation, property checking and problem researching. It is also suggested that the methodology used in the analysis of the problem solving process may be useful for those teachers and researchers who want to integrate Dynamic Geometry Software (DGS) in their classrooms.

  7. Three Proposed Compendia for Genesis Solar Wind Samples: Science Results, Collector Materials Characterization and Cleaning Techniques

    NASA Technical Reports Server (NTRS)

    Allton, J. H.; Calaway, M. J.; Nyquist, L. E.; Jurewicz, A. J. G.; Burnett, D. S.

    2018-01-01

    Final Paper and not the abstract is attached. Introduction: Planetary material and cosmochemistry research using Genesis solar wind samples (including the development and implementation of cleaning and analytical techniques) has matured sufficiently that compilations on several topics, if made publically accessible, would be beneficial for researchers and reviewers. We propose here three compendia based on content, organization and source of documents (e.g. published peer-reviewed, published, internal memos, archives). For planning purposes, suggestions are solicited from potential users of Genesis solar wind samples for the type of science content and/or organizational style that would be most useful to them. These compendia are proposed as living documents, periodically updated. Similar to the existing compendia described below, the curation compendia are like library or archival finding aids, they are guides to published or archival documents and should not be cited as primary sources.

  8. A 15N-poor isotopic composition for the solar system as shown by Genesis solar wind samples.

    PubMed

    Marty, B; Chaussidon, M; Wiens, R C; Jurewicz, A J G; Burnett, D S

    2011-06-24

    The Genesis mission sampled solar wind ions to document the elemental and isotopic compositions of the Sun and, by inference, of the protosolar nebula. Nitrogen was a key target element because the extent and origin of its isotopic variations in solar system materials remain unknown. Isotopic analysis of a Genesis Solar Wind Concentrator target material shows that implanted solar wind nitrogen has a (15)N/(14)N ratio of 2.18 ± 0.02 × 10(-3) (that is, ≈40% poorer in (15)N relative to terrestrial atmosphere). The (15)N/(14)N ratio of the protosolar nebula was 2.27 ± 0.03 × 10(-3), which is the lowest (15)N/(14)N ratio known for solar system objects. This result demonstrates the extreme nitrogen isotopic heterogeneity of the nascent solar system and accounts for the (15)N-depleted components observed in solar system reservoirs.

  9. Preliminary Quantification of Image Color Gradient on Genesis Concentrator Silicon Carbine Target 60001

    NASA Technical Reports Server (NTRS)

    Allton, J. H.; Calaway, M. J.; Rodriquez, M. C.

    2008-01-01

    The Genesis spacecraft concentrator was a device to focus solar wind ions onto a 6-cm diameter target area, thus concentrating the solar wind by 20X [1]. The target area was comprised of 4 quadrants held in place by a gold-coated stainless steel "cross" (Fig. 1). To date, two SiC and one chemical vapor deposited (CVD) quadrants have been imaged at 5X using a Leica DM-6000M in autoscan mode. Complete imaging of SiC sample 60001 required 1036 images. The mosaic of images is shown in Fig. 2 and position of analyzed areas in Fig. 3. This mosaic imaging is part of the curatorial documentation of surface condition and mapping of contamination. Higher magnification (50X) images of selected areas of the target and individual contaminant particles are compiled into reports which may be requested from the Genesis Curator [2].

  10. Slip rate and tremor genesis in Cascadia

    USGS Publications Warehouse

    Wech, Aaron G.; Bartlow, Noel M.

    2014-01-01

    At many plate boundaries, conditions in the transition zone between seismogenic and stable slip produce slow earthquakes. In the Cascadia subduction zone, these events are consistently observed as slow, aseismic slip on the plate interface accompanied by persistent tectonic tremor. However, not all slow slip at other plate boundaries coincides spatially and temporally with tremor, leaving the physics of tremor genesis poorly understood. Here we analyze seismic, geodetic, and strainmeter data in Cascadia to observe for the first time a large, tremor-generating slow earthquake change from tremor-genic to silent and back again. The tremor falls silent at reduced slip speeds when the migrating slip front pauses as it loads the stronger adjacent fault segment to failure. The finding suggests that rheology and slip-speed-regulated stressing rate control tremor genesis, and the same section of fault can slip both with and without detectable tremor, limiting tremor's use as a proxy for slip.

  11. Experiential learning in soil science: Use of an augmented reality sandbox

    NASA Astrophysics Data System (ADS)

    Vaughan, Karen; Vaughan, Robert; Seeley, Janel; Brevik, Eric

    2017-04-01

    It is known widely that greater learning occurs when students are active participants. Novel technologies allow instructors the opportunity to create interactive activities for undergraduate students to gain comprehension of complex landscape processes. We incorporated the use of an Augmented Reality (AR) Sandbox in the Introductory Soil Science course at the University of Wyoming to facilitate an experiential learning experience in pedology. The AR Sandbox was developed by researchers at the University of California, Davis as part of a project on informal science education in freshwater lakes and watershed science. It is a hands-on display that allows users to create topography models by shaping sand that is augmented in real-time by a colored elevation maps, topographic contour lines, and simulated water. It uses a 3-dimensional motion sensing camera that detects changes to the distance between the sand surface and the camera sensor. A short-throw projector then displays the elevation model and contour lines in real-time. Undergraduate students enrolled in the Introductory Soil Science course were tasked with creating a virtual landscape and then predicting where particular soils would form on the various landforms. All participants reported a greater comprehension of surface water flow, erosion, and soil formation as a result of this exercise. They provided suggestions for future activities using the AR Sandbox including its incorporation into lessons of watershed hydrology, land management, soil water, and soil genesis.

  12. Paradoxical Effects of Sodium-Calcium Exchanger Inhibition on Torsade de Pointes and Early Afterdepolarization in a Heart Failure Rabbit Model.

    PubMed

    Chang, Po-Cheng; Lu, Yu-Ying; Lee, Hui-Ling; Lin, Shien-Fong; Chu, Yen; Wen, Ming-Shien; Chou, Chung-Chuan

    2018-05-03

    Calcium homeostasis plays an important role in development of early afterdepolarizations (EADs) and torsade de pointes (TdP). The role of sodium-calcium exchanger (NCX) inhibition in genesis secondary Ca rise and EADs-TdP is still debated. Dual voltage and intracellular Ca optical mapping were conducted in 6 control and 9 failing rabbit hearts. After baseline electrophysiological and optical mapping studies, E4031 was given to simulate long QT syndrome. ORM-10103 was then administrated to examine the electrophysiological effects on EAD-TdP development. E4031 enhanced secondary Ca rise, EADs development and TdP inducibility in both control and failing hearts. The results showed that ORM-10103 reduced premature ventricular beats (PVBs) but was unable to suppress the inducibility of TdP or EADs. The electrophysiological effects of ORM-10103 included prolongation of action potential duration (APD) and increased APD heterogeneity in failing hearts. ORM10103 had a neutral effect on the amplitude of secondary Cai rise in control and HF groups. In this model, most EADs generated from the long-short APD junction area. In conclusion, highly selective NCX inhibition with ORM-10103 reduced PVB burden but was unable to suppress secondary Ca rise, EADs development nor inducibility of TdP. The possible electrophysiological mechanisms include APD prolongation and increased APD heterogeneity.

  13. Experimental Behavior of Sulfur Under Primitive Planetary Differentiation Processes, the Sulfide Formations in Enstatite Meteorites and Implications for Mercury.

    NASA Technical Reports Server (NTRS)

    Malavergne, V.; Brunet, F.; Righter, K.; Zanda, B.; Avril, C.; Borensztajn, S.; Berthet, S.

    2012-01-01

    Enstatite meteorites are the most reduced naturally-occuring materials of the solar system. The cubic monosulfide series with the general formula (Mg,Mn,Ca,Fe)S are common phases in these meteorite groups. The importance of such minerals, their formation, composition and textural relationships for understanding the genesis of enstatite chondrites (EC) and aubrites, has long been recognized (e.g. [1]). However, the mechanisms of formation of these sulfides is still not well constrained certainly because of possible multiple ways to produce them. We propose to simulate different models of formation in order to check their mineralogical, chemical and textural relevancies. The solubility of sulfur in silicate melts is of primary interest for planetary mantles, particularly for the Earth and Mercury. Indeed, these two planets could have formed, at least partly, from EC materials (e.g. [2, 3, 4]). The sulfur content in silicate melts depends on the melt composition but also on pressure (P), temperature (T) and oxygen fugacity fO2. Unfortunately, there is no model of general validity in a wide range of P-T-fO2-composition which describes precisely the evolution of sulfur content in silicate melts, even if the main trends are now known. The second goal of this study is to constrain the sulfur content in silicate melts under reducing conditions and different temperatures.

  14. Acceleration of Ions and Electrons by Coronal Shocks

    NASA Astrophysics Data System (ADS)

    Sandroos, A.

    2013-12-01

    Diffusive shock acceleration (DSA) of particles at collisionless shock waves driven by coronal mass ejections (CMEs) is the best developed theory for the genesis of gradual solar energetic particle (SEP) events. According to DSA, particles scatter from fluctuations present in the ambient magnetic field, which causes some particles to encounter the shock front repeatedly and to gain energy during each crossing. DSA operating in solar corona is a complex process whose outcome depends on multiple parameters such as shock speed and strength, magnetic geometry, and composition of seed particles. Currently, STEREO and other near-Earth spacecraft are providing valuable multi-point information on how SEP properties, such as composition and energy spectra, vary in longitude. Initial results have shown that longitude distributions of large CME-associated SEP events are much wider than previously thought. These findings have many important consequences on SEP modeling. For example, it is important to extend the present models into two or three spatial coordinates to properly account for the effects of coronal and interplanetary magnetic geometry and the evolution of the CME-driven shock wave on the acceleration and transport of SEPs. We present a new model for the shock acceleration of ions and electrons in the solar corona and discuss implications for particle properties (energy spectra, longitudinal distribution, composition) in the resulting gradual SEP events. We also discuss the possible emission of type II radio waves by the accelerated coronal electrons. In the new model, the ion pitch angle scattering rate is calculated from modeled Alfvén wave power spectra using quasilinear theory. The energy gained by ions in scatterings are self-consistently removed from waves so that total energy (ions+waves) is conserved. New model has been implemented on massively parallel simulation platform Corsair.

  15. Acceleration of tropical cyclogenesis by self-aggregation feedbacks

    NASA Astrophysics Data System (ADS)

    Muller, Caroline J.; Romps, David M.

    2018-03-01

    Idealized simulations of tropical moist convection have revealed that clouds can spontaneously clump together in a process called self-aggregation. This results in a state where a moist cloudy region with intense deep convection is surrounded by extremely dry subsiding air devoid of deep convection. Because of the idealized settings of the simulations where it was discovered, the relevance of self-aggregation to the real world is still debated. Here, we show that self-aggregation feedbacks play a leading-order role in the spontaneous genesis of tropical cyclones in cloud-resolving simulations. Those feedbacks accelerate the cyclogenesis process by a factor of 2, and the feedbacks contributing to the cyclone formation show qualitative and quantitative agreement with the self-aggregation process. Once the cyclone is formed, wind-induced surface heat exchange (WISHE) effects dominate, although we find that self-aggregation feedbacks have a small but nonnegligible contribution to the maintenance of the mature cyclone. Our results suggest that self-aggregation, and the framework developed for its study, can help shed more light into the physical processes leading to cyclogenesis and cyclone intensification. In particular, our results point out the importance of the longwave radiative cooling outside the cyclone.

  16. Magma genesis, storage and eruption processes at Aluto volcano, Ethiopia: lessons from remote sensing, gas emissions and geochemistry

    NASA Astrophysics Data System (ADS)

    Hutchison, William; Biggs, Juliet; Mather, Tamsin; Pyle, David; Gleeson, Matthew; Lewi, Elias; Yirgu, Gezahgen; Caliro, Stefano; Chiodini, Giovanni; Fischer, Tobias

    2016-04-01

    One of the most intriguing aspects of magmatism during the transition from continental rifting to sea-floor spreading is that large silicic magmatic systems develop within the rift zone. In the Main Ethiopian Rift (MER) these silicic volcanoes not only pose a significant hazard to local populations but they also sustain major geothermal resources. Understanding the journey magma takes from source to surface beneath these volcanoes is vital for determining its eruption style and for better evaluating the geothermal resources that these complexes host. We investigate Aluto, a restless silicic volcano in the MER, and combine a wide range of geochemical and geophysical techniques to constrain magma genesis, storage and eruption processes and shed light on magmatic-hydrothermal-tectonic interactions. Magma genesis and storage processes at Aluto were evaluated using new whole-rock geochemical data from recent eruptive products. Geochemical modelling confirms that Aluto's peralkaline rhyolites, that constitute the bulk of recent erupted products, are generated from protracted fractionation (>80 %) of basalt that is compositionally similar to rift-related basalts found on the margins of the complex. Crustal melting did not play a significant role in rhyolite genesis and melt storage depths of ~5 km can reproduce almost all aspects of their geochemistry. InSAR methods were then used to investigate magma storage and fluid movement at Aluto during an episode of ground deformation that took place between 2008 and 2010. Combining new SAR imagery from different viewing geometries we identified an accelerating uplift pulse and found that source models support depths of magmatic and/or fluid intrusion at ~5 km for the uplift and shallower depths of ~4 km for the subsidence. Finally, gas samples collected on Aluto in 2014 were used to evaluate magma and fluid transport processes. Our results show that gases are predominantly emanating from major fault zones on Aluto and that they display a clear magmatic carbon signature of -4.2 to -4.5 ‰. This provides compelling evidence that the magmatic and hydrothermal reservoirs of Aluto are physically connected. Bringing the new data sets together provides an integrated picture of the plumbing system of this restless rift volcano. Aluto's silicic magmas are generated and stored at depths of ~5 km. Magmatic intrusion and/or fluid injection in the cap of this magmatic reservoir drives edifice wide inflation while subsequent deflation is related to magmatic degassing and/or cooling of the geothermal reservoir at shallower depths. Tectonic faults that dissect the complex are a key component of this plumbing system and by connecting the deep reservoirs to the surface they not only provide important degassing pathways but will almost certainly be exploited during future eruptive events.

  17. Pediatric sexology and hermaphroditism.

    PubMed

    Money, J

    1985-01-01

    Lacking an empirically based theory of erotosexual development and health in childhood, pediatrics too easily falls back on reductionistic hypotheses of the nature versus nurture type. A new, three-term paradigm, namely, nature/critical-period/nurture, is needed to explain, for example, the phenomenology of hermaphroditism, and the differentiation of gender-identity/role (G-I/R) in individual cases. In 30 young women with a history of the early-treated, 46,XX congenital virilizing adrenal hyperplasia (CVAH) syndrome, 37% (N = 11) had a history of bisexual imagery or practice, as compared with 7% in the control patients (chi 2 = 17.7; p less than .001); and 5 of these 11 rated themselves as exclusively or predominantly lesbian. In Kinsey's sample, 15% of females reported homoerotic imagery by age 20, and 2 out of 3 of them also had homoerotic partner contact. The CVAH finding may be a function of prenatal and/or neonatal brain androgenization, but other variables, such as the history of juvenile erotosexual rehearsal play, cannot be ruled out. Among adolescents with a history of hermaphroditism, sex-reassignment applications are honored predominantly if they are made by 46,XY hermaphrodites assigned neonatally as girls and with nonfeminizing hormonal puberty, as medical and folk traditions both favor approval of such applicants more than others. Parthenogenic whiptail lizards that alternately simulate the male and female mating behavior of related diecious species provide an animal model that demonstrates the existence of both male and female sexual schemas in the same brain. In human beings, the irreducible sex differences are that males impregnate, and females menstruate, gestate, and lactate. Otherwise, sexual dimorphism that is programmed into the brain under the influence of prenatal hormones appears to be not sex-irreducible, but sex-shared and threshold-dimorphic. A complete theory of the differentiation of all the constituents of masculinity or femininity of G-I/R needs to be both multivariate and sequential in type. It must be applicable to all of the syndromes of hermaphroditism, and to the genesis of all the G-I/R phenomena, including transvestism and transsexualism, as well as to the genesis of a heterosexual G-I/R.

  18. Modulation of the intraseasonal Indo-western Pacific convection oscillation to tropical cyclogenesis location and frequency over the Indo-western North Pacific during boreal extended summer

    NASA Astrophysics Data System (ADS)

    Wang, Qiuyun; Li, Jianping; Li, Yanjie; Zhang, Jingwen

    2017-04-01

    The influence of the intraseasonal Indo-western Pacific convection oscillation (IPCO) on the tropical cyclone (TC) genesis location and frequency over the Indo-western North Pacific during the boreal extended summer (May-October) is explored in this paper. Observational analysis shows that the impacts of the intraseasonal IPCO on TCs over the Indo-western North Pacific features in evident "locational phase lock of TC genesis" and distinct differences in TC frequency. In term of the WNP, when the intraseasonal IPCO is positive phase, there tends to be much more TCs, especially in the South China Sea (SCS), and more TCs generate in the west of the WNP and lower latitude (around 5°-20°N); vice versa. At the positive intraseasonal IPCO phase, the atmosphere gains heat through both sea-air interaction and the latent heat release of cumulus convective condensation, and the anomalous cyclonic circulation weakens the western Pacific subtropical high (WPSH), these conditions do favor the TC genesis. Moreover, the shrinking WPSH, the enhanced heat transfer from sea to air at the lower latitude as well as the westward shifts of heating center and anomalous cyclonic circulation lock TC genesis locations in the west of the WNP and lower latitude. The opposite situation occurs at negative phase. As for the North Indian Ocean (NIO), the TC genesis locations at the positive intraseasonal IPCO phase mainly situate in 13°-20°N and distribute closer to Indian Peninsula, particularly in the Arabian Sea (ARB), in contrast, the spatial distribution is more dispersed at the negative intraseasonal IPCO phase. However, the total TC frequencies at two intraseasonal IPCO phases are similar. These features come largely from the differences in the area featuring conditions between the northern and southern regions of 13°N in the NIO: at the positive intraseasonal IPCO phase, to the northern region of 13°N, the environmental conditions are similar to the case of the WNP except without the WPSH control, and the reversed situations are observed over the southern region of 13°N, which lead to northward shift of TC genesis location. The negative phase reflects an opposite situation.

  19. Pb, Sr, and Nd isotopic compositions of a suite of Large Archean, igneous rocks, eastern Beartooth Mountains - Implications for crust-mantle evolution

    NASA Technical Reports Server (NTRS)

    Wooden, J. L.; Mueller, P. A.

    1988-01-01

    Compositionally diverse Late Archean rocks (2.74-2.79 Ga old) from the eastern Beartooth Mountains (Montana and Wyoming) were studied and shown to have the same initial Pb, Sr, and Nd isotopic ratios. Lead and Sr initial ratios are higher and Nd initial values lower than predicted for rocks derived from model mantle sources and strongly indicate the involvement of an older crustal reservoir in the genesis of these rocks. A model involving subduction of continental detritus and contamination of the overlying mantle is suggested.

  20. Stereomicroscope Inspection of Polished Aluminum Collector 50684.0

    NASA Technical Reports Server (NTRS)

    Rodriquez, M. C.; Calaway, M. J.; Allton, J. H.

    2008-01-01

    The Genesis polished aluminum "kidney" collector was damaged during the hard landing of the capsule on September 8, 2004 in the Utah desert. The kidney was introduced into the Genesis (ISO class 4) cleanroom laboratory on November 4, 2004 and stored under nitrogen cover gas. The collector is currently fastened to a highly polished stainless steel plate for secure handling. Curatorial work at JSC has made successful subdivision and subsequent allocation of samples from the kidney.

  1. Potential Vorticity Streamers as Precursors to Tropical Cyclone Genesis in the Western Pacific

    DTIC Science & Technology

    2012-03-01

    study a developing system with an extratropical precursor (TCS-037) developing into Tropical Storm 16W (TS 16W)” (Schönenberger 2010). This subsection...tropopause maps), the TC genesis event is termed a tropical transition (TT) case. If no such extratropical feature 38 is present, the storm in... extratropical origin is deemed to play an important role in the dynamical evolution leading to tropical cyclogenesis. In contrast, non-TT storms

  2. Astronaut David Scott - Sample - "Genesis Rock" - MSC

    NASA Image and Video Library

    1971-08-12

    S71-43477 (12 Aug. 1971) --- Astronaut David R. Scott, right, commander of the Apollo 15 mission, gets a close look at the sample referred to as "Genesis rock" in the Non-Sterile Nitrogen Processing Line (NNPL) in the Lunar Receiving Laboratory (LRL) at the Manned Spacecraft Center (MSC). Scientist-astronaut Joseph P. Allen IV, left, an Apollo 15 spacecraft communicator, looks on with interest. The white-colored rock has been given the permanent identification of 15415.

  3. Genesis & the Human Ribcage: An Opportunity to Correct a Misconception & Introduce an Evolution Lesson into the Anatomy Class

    ERIC Educational Resources Information Center

    Senter, Phil

    2013-01-01

    Many anatomy students begin the course with a misconception that human males and females do not have the same number of ribs. At the root of that misconception is Genesis 2:21-22, in which God removes a rib from Adam to make Eve. Removal of a body part is a surgical procedure, and one does not pass on the results of surgery to one's offspring. The…

  4. Hurricane intensification along United States coast suppressed during active hurricane periods

    NASA Astrophysics Data System (ADS)

    Kossin, James P.

    2017-01-01

    The North Atlantic ocean/atmosphere environment exhibits pronounced interdecadal variability that is known to strongly modulate Atlantic hurricane activity. Variability in sea surface temperature (SST) is correlated with hurricane variability through its relationship with the genesis and thermodynamic potential intensity of hurricanes. Another key factor that governs the genesis and intensity of hurricanes is ambient environmental vertical wind shear (VWS). Warmer SSTs generally correlate with more frequent genesis and greater potential intensity, while VWS inhibits genesis and prevents any hurricanes that do form from reaching their potential intensity. When averaged over the main hurricane-development region in the Atlantic, SST and VWS co-vary inversely, so that the two factors act in concert to either enhance or inhibit basin-wide hurricane activity. Here I show, however, that conditions conducive to greater basin-wide Atlantic hurricane activity occur together with conditions for more probable weakening of hurricanes near the United States coast. Thus, the VWS and SST form a protective barrier along the United States coast during periods of heightened basin-wide hurricane activity. Conversely, during the most-recent period of basin-wide quiescence, hurricanes (and particularly major hurricanes) near the United States coast, although substantially less frequent, exhibited much greater variability in their rate of intensification, and were much more likely to intensify rapidly. Such heightened variability poses greater challenges to operational forecasting and, consequently, greater coastal risk during hurricane events.

  5. NR2A contributes to genesis and propagation of cortical spreading depression in rats.

    PubMed

    Bu, Fan; Du, Ruoxing; Li, Yi; Quinn, John P; Wang, Minyan

    2016-03-22

    Cortical spreading depression (CSD) is a transient propagating excitation of synaptic activity followed by depression, which is implicated in migraine. Increasing evidence points to an essential role of NR2A-containing NMDA receptors in CSD propagation in vitro; however, whether these receptors mediate CSD genesis in vivo requires clarification and the role of NR2A on CSD propagation is still under debate. Using in vivo CSD in rats with electrophysiology and in vitro CSD in chick retina with intrinsic optical imaging, we addressed the role of NR2A in CSD. We demonstrated that NVP-AAM077, a potent antagonist for NR2A-containing receptors, perfused through microdialysis probes, markedly reduced cortex susceptibility to CSD, but also reduced magnitude of CSD genesis in rats. Additionally, NVP-AAM077 at 0.3 nmol perfused into the contralateral ventricle, considerably suppressed the magnitude of CSD propagation wave and propagation rate in rats. This reduction in CSD propagation was also observed with TCN-201, a negative allosteric modulator selective for NR2A, at 3 μM, in the chick retina. Our data provides strong evidence that NR2A subunit contributes to CSD genesis and propagation, suggesting drugs selectively antagonizing NR2A-containing receptors might constitute a highly specific strategy treating CSD associated migraine with a likely better safety profile.

  6. NR2A contributes to genesis and propagation of cortical spreading depression in rats

    PubMed Central

    Bu, Fan; Du, Ruoxing; Li, Yi; Quinn, John P; Wang, Minyan

    2016-01-01

    Cortical spreading depression (CSD) is a transient propagating excitation of synaptic activity followed by depression, which is implicated in migraine. Increasing evidence points to an essential role of NR2A-containing NMDA receptors in CSD propagation in vitro; however, whether these receptors mediate CSD genesis in vivo requires clarification and the role of NR2A on CSD propagation is still under debate. Using in vivo CSD in rats with electrophysiology and in vitro CSD in chick retina with intrinsic optical imaging, we addressed the role of NR2A in CSD. We demonstrated that NVP-AAM077, a potent antagonist for NR2A-containing receptors, perfused through microdialysis probes, markedly reduced cortex susceptibility to CSD, but also reduced magnitude of CSD genesis in rats. Additionally, NVP-AAM077 at 0.3 nmol perfused into the contralateral ventricle, considerably suppressed the magnitude of CSD propagation wave and propagation rate in rats. This reduction in CSD propagation was also observed with TCN-201, a negative allosteric modulator selective for NR2A, at 3 μM, in the chick retina. Our data provides strong evidence that NR2A subunit contributes to CSD genesis and propagation, suggesting drugs selectively antagonizing NR2A-containing receptors might constitute a highly specific strategy treating CSD associated migraine with a likely better safety profile. PMID:27001011

  7. Genesis Solar-Wind Sample Return Mission: The Materials

    NASA Technical Reports Server (NTRS)

    Jurewicz, A. J. G.; Burnett, D. S.; Wiens, R. C.; Woolum, D.

    2003-01-01

    The Genesis spacecraft has two primary instruments which passively collect solar wind. The first is the collector arrays , a set of panels, each of which can deploy separately to sample the different kinds of solar wind (regimes). The second is the concentrator, an electrostatic mirror which will concentrate ions of mass 4 through mass 25 by about a factor of 20 by focusing them onto a 6 cm diameter target. When not deployed, these instruments fit into a compact canister. After a two year exposure time, the deployed instruments can be folded up, sealed into the canister, and returned to earth for laboratory analysis. Both the collector arrays and the concentrator will contain suites of ultra-high purity target materials, each of which is tailored to enable the analysis of a different family of elements. This abstract is meant to give a brief overview of the Genesis mission, insight into what materials were chosen for flight and why, as well as head s up information as to what will be available to planetary scientist for analysis when the solar-wind samples return to Earth in 2003. Earth. The elemental and isotopic abundances of the solar wind will be analyzed in state-of-the-art laboratories, and a portion of the sample will be archived for the use of future generations of planetary scientists. Technical information about the mission can be found at www.gps.caltech.edu/genesis.

  8. Genesis of Pre-Hurricane Felix (2007). Part I: The Role of the Easterly Wave Critical Layer

    DTIC Science & Technology

    2010-06-01

    the boundary layer does not overcome the positive entropy flux from the ocean surface. As suggested by Montgomery et al. (2006), cold pools of...Weather Research and Forecasting (WRF) model with a high-resolution nested grid configuration that permits the representation of cloud system processes...from the jet level to the top of the atmospheric boundary layer. The region of a quasi-closed Lagrangian circulation within the wave pouch provides a

  9. Erosion of Northern Reservoir Shores: An Analysis and Application of Pertinent Literature,

    DTIC Science & Technology

    1985-05-01

    classification of tills and criteria for distinguishing tills of different origins. Geografia , 12: 65-80. Boulton, G.S. (1978) The genesis of glacial tills...northwestern Gulf of Mexico . Marine Geotechnology, 2: 9- 41. 145 Collins, J.I. (1976) Approaches to wave modeling. Society of Economic Paleontologists and...transport by waves and currents. In Proceedings, 8th Coastal Engineering Confer- ence, Mexico City, pp. 137-150. Ippen, A.T. and P.S. Eagleson (195) A study

  10. Genesis of highland basalt breccias - A view from 66095

    NASA Technical Reports Server (NTRS)

    Garrison, J. R., Jr.; Taylor, L. A.

    1980-01-01

    Electron microprobe and defocused beam analyses of the lunar highland breccia sample 66095 show it consists of a fine-grained subophitic matrix containing a variety of mineral and lithic clasts, such as intergranular and cataclastic ANT, shocked and unshocked plagioclase, and basalts. Consideration of the chemistries of both matrix and clasts provides a basis for a qualitative three-component mixing model consisting of an ANT plutonic complex, a Fra Mauro basalt, and minor meteoric material.

  11. Genesis Field Recovery

    NASA Technical Reports Server (NTRS)

    McNamara, K. M.

    2005-01-01

    The Genesis mission returned to Earth on September 8, 2004 after a nearly flawless three-year mission to collect solar matter. The intent was to deploy a drogue chute and parafoil high over the Utah desert and to catch the fragile payload capsule in mid-air by helicopter. The capsule would then be opened in a clean-room constructed for that purpose at UTTR, and a nitrogen purge was to be installed before transporting the science canister to JSC. Unfortunately, both chutes failed to deploy, causing the capsule to fall to the desert floor at a speed of nearly 200 MPH. Still, Genesis represents a milestone in the US space program, comprising the first sample return since the Apollo Missions as well as the first return of materials exposed to the space environment outside of low Earth orbit and beyond the Earth s magnetosphere for an extended period. We have no other comparable materials in all of our collections on Earth. The goal of the Genesis Mission was to collect a representative sample of the composition of the solar wind and thus, the solar nebula from which our solar system originated. This was done by allowing the naturally accelerated species to implant shallowly in the surfaces of ultra-pure, ultra-clean collector materials. These collectors included single crystal silicon (FZ and CZ), sapphire, silicon carbide; those materials coated with aluminum, silicon, diamond like carbon, and gold; and isotopically enriched polycrystalline diamond and amorphous carbon. The majority of these materials were distributed on five collector arrays. Three of the materials were housed in an electrostatic concentrator designed to increase the flux of low-mass ions. There was also a two-inch diameter bulk metallic glass collector and a gold foil, polished aluminum, and molybdenum coated platinum foil collector. An excellent review of the Genesis collector materials is offered in reference [1].

  12. A Conundrum of Tropical Cyclone Formation

    NASA Astrophysics Data System (ADS)

    Davis, C. A.

    2014-12-01

    This paper will address a conundrum that has emerged from recent research on tropical cyclone formation. Composite analyses and case studies suggest that prior to genesis, the atmosphere presents a mid-tropospheric vortex that is strong compared to the cyclonic circulation in the boundary layer. Accompanying this vortex is near saturation from the boundary layer through at least 5 km, sometimes more, and a nearly balanced weak negative temperature anomaly below the vortex and stronger positive temperature anomaly above. This thermodynamic state is one of high moisture but low buoyancy for lifted parcels (i.e. low convective available potential energy). However, observations also suggest that widespread deep convection accompanies genesis, with cloud top temperatures becoming colder near the time of genesis. This is seemingly at odds with in situ observations of thermodynamic characteristics prior to genesis. Progress toward understanding the apparent contradiction can be made by realizing that the existence of a moist, relatively stable vortex, and deep convective clouds are not necessarily coincident in space and time. This is demonstrated by a detailed analysis of the two days leading up to the formation of Atlantic tropical cyclone Karl on 14 September. Karl featured a relatively long gestation period characterized initially by a marked misalignment of mid-tropospheric and surface cyclonic circulations. The mid-tropospheric vortex strengthened due to a pulse of convection earlier on 13 September. Meanwhile, the near-surface vortex underwent a precession around the mid-tropospheric vortex as the separation between the two decreased. The eruption of convection around midnight on 14 September, 18 hours prior to declaration on a TC, occurred in the center of the nearly-aligned vortex, contained a mixture of shallow and deep convection and resulted in spin-up over a deep layer, but particularly at the surface. Prior to genesis, the most intense deep convection was located at least 200 km from the center.

  13. Size Distribution of Genesis Solar Wind Array Collector Fragments Recovered

    NASA Technical Reports Server (NTRS)

    Allton, J. H.; Stansbery, E. K.; McNamara, K. M.

    2005-01-01

    Genesis launched in 2001 with 271 whole and 30 half hexagonally-shaped collectors mounted on 5 arrays, comprised of 9 materials described in [1]. The array collectors were damaged during re-entry impact in Utah in 2004 [2], breaking into many smaller pieces and dust. A compilation of the number and approximate size of the fragments recovered was compiled from notes made during the field packaging performed in the Class 10,000 cleanroom at Utah Test and Training Range [3].

  14. Public Risk Assessment of Off-Nominal Genesis Entries

    NASA Technical Reports Server (NTRS)

    Mendeck, Gavin F.; Kadwa, Binaifer

    2006-01-01

    Public risk estimations were among the preparations for the entry of the Genesis sample return capsule. Personnel at the Johnson Space Center were requested to provide estimates of the public risk of off-nominal entries. These scenarios dealt with an incomplete trajectory maneuver that would result in the capsule landing outside of the controlled Utah Test and Training Range. Using a conservative approach to the inputs and assumptions, such off-nominal entries were demonstrated to fall within the project risk limits.

  15. Unique variable polarity plasma arc welding for space shuttle

    NASA Technical Reports Server (NTRS)

    Schwinghamer, R. J.

    1985-01-01

    Since the introduction of the Plasma Arc Torch in 1955 and subsequent to the work at Boeing in the 1960's, significant improvements crucial to success have been made in the Variable Polarity Plasma Arc (VPPA) Process at the Marshall Space Flight Center. Several very important advantages to this process are given, and the genesis of PA welding, the genesis of VPPA welding, special equiment requirements, weld property development, results with other aluminum alloys, and the eventual successful VPPA transition to production operations are discussed.

  16. Rock flows

    NASA Technical Reports Server (NTRS)

    Matveyev, S. N.

    1986-01-01

    Rock flows are defined as forms of spontaneous mass movements, commonly found in mountainous countries, which have been studied very little. The article considers formations known as rock rivers, rock flows, boulder flows, boulder stria, gravel flows, rock seas, and rubble seas. It describes their genesis as seen from their morphological characteristics and presents a classification of these forms. This classification is based on the difference in the genesis of the rubbly matter and characterizes these forms of mass movement according to their source, drainage, and deposit areas.

  17. Mesoscale atmospheric modelling technology as a tool for the long-term meteorological dataset development

    NASA Astrophysics Data System (ADS)

    Platonov, Vladimir; Kislov, Alexander; Rivin, Gdaly; Varentsov, Mikhail; Rozinkina, Inna; Nikitin, Mikhail; Chumakov, Mikhail

    2017-04-01

    The detailed hydrodynamic modelling of meteorological parameters during the last 30 years (1985 - 2014) was performed for the Okhotsk Sea and the Sakhalin island regions. The regional non-hydrostatic atmospheric model COSMO-CLM used for this long-term simulation with 13.2, 6.6 and 2.2 km horizontal resolutions. The main objective of creation this dataset was the outlook of the investigation of statistical characteristics and the physical mechanisms of extreme weather events (primarily, wind speed extremes) on the small spatio-temporal scales. COSMO-CLM is the climate version of the well-known mesoscale COSMO model, including some modifications and extensions adapting to the long-term numerical experiments. The downscaling technique was realized and developed for the long-term simulations with three consequent nesting domains. ERA-Interim reanalysis ( 0.75 degrees resolution) used as global forcing data for the starting domain ( 13.2 km horizontal resolution), then these simulation data used as initial and boundary conditions for the next model runs over the domain with 6.6 km resolution, and similarly, for the next step to 2.2 km domain. Besides, the COSMO-CLM model configuration for 13.2 km run included the spectral nudging technique, i.e. an additional assimilation of reanalysis data not only at boundaries, but also inside the whole domain. Practically, this computational scheme realized on the SGI Altix 4700 supercomputer system in the Main Computer Center of Roshydromet and used 2,400 hours of CPU time total. According to modelling results, the verification of the obtained dataset was performed on the observation data. Estimations showed the mean error -0.5 0C, up to 2 - 3 0C RMSE in temperature, and overestimation in wind speed (RMSE is up to 2 m/s). Overall, analysis showed that the used downscaling technique with applying the COSMO-CLM model reproduced the meteorological conditions, spatial distribution, seasonal and synoptic variability of temperature and wind speed for the study area adequately. The dependences between reproduction quality of mesoscale atmospheric circulation features and the horizontal resolution of the model were revealed. In particular, it is shown that the use of 6 km resolution does not give any significant improvement comparing to 13 km resolution, whereas 2.2 km resolution provides an appreciable quality enhancement. Detailed synoptic analysis of extreme wind speed situations identified the main types of favorable to their genesis, associated with developing of cyclones over the Japan Islands or the Primorsky Kray of Russia, and penetration of intensified cyclones from Pacific Ocean through the Kamchatka peninsula, Kuril or Japan Islands. The obtained dataset will continue to be used for a full and comprehensive analysis of the reproduction quality of hydrometeorological fields, their statistical estimates, climatological trends and many other objectives.

  18. Continuous data assimilation experiments with the NMC eta model: A GALE IOP 1 case study. [NMC (National Meteorological Center); GALE IOP (Genesis of Atlantic Lows Experiment intensive observing period)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ramamurthy, M.K.; Xu, T.Y.

    1993-11-01

    The current major expansion in observational capability of the National Weather Service is principally in the volume of asynchronous data rather than synchronous observations at the standard synoptic times. Hence, the National Meteorological Center is considering a continuous data assimilation system to replace at some time the intermittent system now used by its regional and global operational models. We describe this system, based on the Newtonian relaxation technique, as developed for the eta model. Experiments are performed for the first intensive observing period of the Genesis of Atlantic Lows Experiment (GALE) in January 1986, when strong upper-level cyclogenesis occurred, withmore » a pronounced tropopause fold but only modest surface development. The GALE level IIIb dataset was used for initializing and updating the model. Issues addressed in the experiments include choice of update variable, number, and length of update segments; need for updating moisture and surface pressure information; nudging along boundaries; and noise control. Assimilation of data from a single level was also studied. Use of a preforecast assimilation cycle was found to eliminate the spinup problem almost entirely. Multiple, shorter assimilation segments produced better forecasts than a single, longer cycle. Updating the mass field was less effective than nudging the wind field but assimilating both was best. Assimilation of moisture data, surprisingly, affected the spinup adversely, but nudging the surface pressure information reduced the spurious pillow effect. Assimilation of single-level information was ineffective unless accompanied by increased vertical coupling, obtained from a control integration. 52 refs., 19 figs., 1 tab.« less

  19. Ordinary chondrites - Multivariate statistical analysis of trace element contents

    NASA Technical Reports Server (NTRS)

    Lipschutz, Michael E.; Samuels, Stephen M.

    1991-01-01

    The contents of mobile trace elements (Co, Au, Sb, Ga, Se, Rb, Cs, Te, Bi, Ag, In, Tl, Zn, and Cd) in Antarctic and non-Antarctic populations of H4-6 and L4-6 chondrites, were compared using standard multivariate discriminant functions borrowed from linear discriminant analysis and logistic regression. A nonstandard randomization-simulation method was developed, making it possible to carry out probability assignments on a distribution-free basis. Compositional differences were found both between the Antarctic and non-Antarctic H4-6 chondrite populations and between two L4-6 chondrite populations. It is shown that, for various types of meteorites (in particular, for the H4-6 chondrites), the Antarctic/non-Antarctic compositional difference is due to preterrestrial differences in the genesis of their parent materials.

  20. Combined Effects of Deforestation and Doubled Atmospheric CO2 Concentrations on the Climate of Amazonia.

    NASA Astrophysics Data System (ADS)

    Costa, Marcos Heil; Foley, Jonathan A.

    2000-01-01

    It is generally expected that the Amazon basin will experience at least two major environmental changes during the next few decades and centuries: 1) increasing areas of forest will be converted to pasture and cropland, and 2) concentrations of atmospheric CO2 will continue to rise. In this study, the authors use the National Center for Atmospheric Research GENESIS atmospheric general circulation model, coupled to the Integrated Biosphere Simulator, to determine the combined effects of large-scale deforestation and increased CO2 concentrations (including both physiological and radiative effects) on Amazonian climate.In these simulations, deforestation decreases basin-average precipitation by 0.73 mm day1 over the basin, as a consequence of the general reduction in vertical motion above the deforested area (although there are some small regions with increased vertical motion). The overall effect of doubled CO2 concentrations in Amazonia is an increase in basin-average precipitation of 0.28 mm day1. The combined effect of deforestation and doubled CO2, including the interactions among the processes, is a decrease in the basin-average precipitation of 0.42 mm day1. While the effects of deforestation and increasing CO2 concentrations on precipitation tend to counteract one another, both processes work to warm the Amazon basin. The effect of deforestation and increasing CO2 concentrations both tend to increase surface temperature, mainly because of decreases in evapotranspiration and the radiative effect of CO2. The combined effect of deforestation and doubled CO2, including the interactions among the processes, increases the basin-average temperature by roughly 3.5°C.

  1. Long-Term Changes in the Extreme Significant Wave Heights on the Western North Pacific: Impacts of Tropical Cyclone Activity and ENSO

    NASA Astrophysics Data System (ADS)

    Yang, Sinil; Oh, Jaiho

    2018-02-01

    Seasonal extreme wave statistics were reproduced by using the 25-km-grid global wave model of WAVEWATCH-III. The results showed that the simulated wave dataset for the present climate (1979-2009) was similar to Climate Forecast System Reanalysis (CFSR) wave data. Statistics such as the root mean squared error (RMSE) and correlation coefficient (CC) over the western North Pacific (WNP) basin were 0.5 m and 0.69 over the analysis domain. The largest trends and standard deviation were around the southern coast of Japan and western edge of the WNP. Linear regression analysis was employed to identify the relationship between the leading principal components (PCs) of significant wave heights (SWHs) in the peak season of July to September and sea surface temperature (SST) anomalies in the equatorial Pacific. The results indicated that the inter-annual variability of SWH can be associated with the El Niño-Southern Oscillation in the peak season. The CC between the first PC of the SWH and anomalies in the Nino 3.4 SST index was also significant at a 99% confidence level. Significant variations in the SWH are affected by tropical cyclones (TCs) caused by increased SST anomalies. The genesis and development of simulated TCs can be important to the variation in SWHs for the WNP in the peak season. Therefore, we can project the variability of SWHs through TC activity based on changes in SST conditions for the equatorial Pacific in the future.

  2. The NASA EV-2 CYGNSS Small Satellite Constellation Mission

    NASA Astrophysics Data System (ADS)

    Ruf, C. S.; Gleason, S.; Jelenak, Z.; Katzberg, S. J.; Ridley, A. J.; Rose, R.; Scherrer, J.; Zavorotny, V.

    2012-12-01

    The NASA EV-2 Cyclone Global Navigation Satellite System (CYGNSS) is a spaceborne mission focused on tropical cyclone (TC) inner core process studies. CYGNSS attempts to resolve the principle deficiencies with current TC intensity forecasts, which lies in inadequate observations and modeling of the inner core. The inadequacy in observations results from two causes: 1) Much of the inner core ocean surface is obscured from conventional remote sensing instruments by intense precipitation in the eye wall and inner rain bands. 2) The rapidly evolving (genesis and intensification) stages of the TC life cycle are poorly sampled in time by conventional polar-orbiting, wide-swath surface wind imagers. CYGNSS is specifically designed to address these two limitations by combining the all-weather performance of GNSS bistatic ocean surface scatterometry with the sampling properties of a constellation of satellites. The use of a dense constellation of nanosatellite results in spatial and temporal sampling properties that are markedly different from conventional imagers. Simulation studies will be presented which examine the sampling as functions of various orbit parameters of the constellation. Historical records of actual TC storm tracks are overlaid onto a simulated time series of the surface wind sampling enabled by the constellation. For comparison purposes, a similar analysis is conducted using the sampling properties of several past and present conventional spaceborne ocean wind scatterometers. Differences in the ability of the sensors to resolve the evolution of the TC inner core are examined. The spacecraft and constellation mission are described. The signal-to-noise ratio of the measured scattered signal and the resulting uncertainty in retrieved surface wind speed are also examined.

  3. Analysis of Molecular Contamination on Genesis Collectors Through Spectroscopic Ellipsometry

    NASA Technical Reports Server (NTRS)

    McNamara, K. M.; Stansbery, Eileen K.

    2005-01-01

    Before the spacecraft returned to Earth in September, the Genesis mission had a preliminary assessment plan in place for the purpose of providing information on the condition and availability of collector materials to the science community as a basis for allocation requests. One important component of that plan was the evaluation of collector surfaces for molecular contamination. Sources of molecular contamination might be the on-orbit outgassing of spacecraft and science canister components, the condensation of thruster by-products during spacecraft maneuvers, or the condensation of volatile species associated with reentry. Although the non-nominal return of the Genesis spacecraft introduced particulate contamination to the collectors, such as dust and heatshield carbon-carbon, it is unlikely to have caused any molecular deposition. The contingency team's quick action in returning the damaged payload the UTTR cleanroom by 6 PM the evening of recovery help to ensure that exposure to weather conditions and the environment were kept to a minimum.

  4. Bi-Parental Care Contributes to Sexually Dimorphic Neural Cell Genesis in the Adult Mammalian Brain

    PubMed Central

    Mak, Gloria K.; Antle, Michael C.; Dyck, Richard H.; Weiss, Samuel

    2013-01-01

    Early life events can modulate brain development to produce persistent physiological and behavioural phenotypes that are transmissible across generations. However, whether neural precursor cells are altered by early life events, to produce persistent and transmissible behavioural changes, is unknown. Here, we show that bi-parental care, in early life, increases neural cell genesis in the adult rodent brain in a sexually dimorphic manner. Bi-parentally raised male mice display enhanced adult dentate gyrus neurogenesis, which improves hippocampal neurogenesis-dependent learning and memory. Female mice display enhanced adult white matter oligodendrocyte production, which increases proficiency in bilateral motor coordination and preference for social investigation. Surprisingly, single parent-raised male and female offspring, whose fathers and mothers received bi-parental care, respectively, display a similar enhancement in adult neural cell genesis and phenotypic behaviour. Therefore, neural plasticity and behavioural effects due to bi-parental care persist throughout life and are transmitted to the next generation. PMID:23650527

  5. Using Image Pro Plus Software to Develop Particle Mapping on Genesis Solar Wind Collector Surfaces

    NASA Technical Reports Server (NTRS)

    Rodriquez, Melissa C.; Allton, J. H.; Burkett, P. J.

    2012-01-01

    The continued success of the Genesis mission science team in analyzing solar wind collector array samples is partially based on close collaboration of the JSC curation team with science team members who develop cleaning techniques and those who assess elemental cleanliness at the levels of detection. The goal of this collaboration is to develop a reservoir of solar wind collectors of known cleanliness to be available to investigators. The heart and driving force behind this effort is Genesis mission PI Don Burnett. While JSC contributes characterization, safe clean storage, and benign collector cleaning with ultrapure water (UPW) and UV ozone, Burnett has coordinated more exotic and rigorous cleaning which is contributed by science team members. He also coordinates cleanliness assessment requiring expertise and instruments not available in curation, such as XPS, TRXRF [1,2] and synchrotron TRXRF. JSC participates by optically documenting the particle distributions as cleaning steps progress. Thus, optical document supplements SEM imaging and analysis, and elemental assessment by TRXRF.

  6. A test of ecological optimality for semiarid vegetation. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Salvucci, Guido D.; Eagleson, Peter S.; Turner, Edmund K.

    1992-01-01

    Three ecological optimality hypotheses which have utility in parameter reduction and estimation in a climate-soil-vegetation water balance model are reviewed and tested. The first hypothesis involves short term optimization of vegetative canopy density through equilibrium soil moisture maximization. The second hypothesis involves vegetation type selection again through soil moisture maximization, and the third involves soil genesis through plant induced modification of soil hydraulic properties to values which result in a maximum rate of biomass productivity.

  7. Marine Cloud Brightening: regional applications to the weakening of hurricanes and reduction in coral bleaching

    NASA Astrophysics Data System (ADS)

    Gadian, A.; Hauser, R.; Kleypas, J. A.; Latham, J.; Parkes, B.; Salter, S.

    2013-12-01

    This study examines the potential to cool ocean surface waters in regions of hurricane genesis and early development. This would be achieved by seeding, with copious quantities of seawater cloud condensation nuclei (CCN), low-level maritime stratocumulus clouds covering these regions or those at the source of incoming currents. Higher cloud droplet density would increase these clouds' reflectivity to incoming sunlight, and possibly their longevity. This approach is a more localized application of the Marine Cloud Brightening (MCB) geoengineering technique promoting global cooling. By utilizing a climate ocean/atmosphere coupled model, HadGEM1, and by judicious seeding of maritime stratocumulus clouds, we demonstrate that we may be able to significantly reduce sea surface temperatures (SSTs) in hurricane development regions. Thus artificial seeding may reduce hurricane intensity; but how well the magnitude of this effect is yet to be determined. Increases in coral bleaching events over the last few decades have been largely caused by rising SSTs, and continued warming is expected to cause even greater increases through this century. Using thr same Global Climate Model to examine the potential of MCB to cool oceanic surface waters in three coral reef provinces. Our simulations indicate that under doubled CO2 conditions, the substantial increases in coral bleaching conditions from current values in three reef regions (Caribbean, French Polynesia, and the Great Barrier Reef) were eliminated when MCB was applied, which reduced the SSTs at these sites roughly to their original values. In this study we also illustrate how even regional application of MCB can affect the planetary meridional heat flux and the reduction in poleward heat transfer. (a) Change in annual average sea surface temperature, Celsius, between the 2xCO2 and CONTROL simulations. (b) Change in annual average sea surface temperature, Celsius, between the CONTROL and 2xCO2+MCB simulations. The dashed black boxes in both panels represent the three coral reef regions. In the Southern north Atlantic, the warmer SSTs in (a) is reduced to the current "control" temperatures, weakening hurricane formation.

  8. A Revised Similarity Law in Botanic Describes the Genesis of the Vulnerability Curve Shape in Vascular Plants

    NASA Astrophysics Data System (ADS)

    Mrad, A.; Domec, J. C.; Huang, C. W.; Katul, G. G.

    2017-12-01

    Xylem tissues are specialized in offering the least possible resistance to water flow. However, this is not guaranteed when ascending sap reaches large negative pressures during periods of water stress when embolism within the xylem occurs, an inevitable step toward potential drought-induced mortality. Ongoing research into changing forest patterns and plant survival due to droughts rarely dispute the significance of Vulnerability Curves (VCs), plots that feature loss in relative conductance with declining liquid pressure (ψ). While Earth-Systems models routinely employ various VC functions, the theoretical underpinnings describing their shape remains lacking. VCs are the outcome of microscopic phenomena describing embolism formation, bubble-scale xylem properties allowing embolism spread, and hydraulic processes that dictate the water potential along the flow path. The work here explores how the upscaled version of these gives rise to popular mathematical shapes used to describe VC measurements: The Logistic and Weibull exceedance equations. Each of these two captures a distinct type of embolism spread: The Logistic VC arises when the probability that embolized vessels interact with intact ones describe embolism spread as water pressure decreases (labeled as a similarity law in botanic [1]). The Weibull VC arises when the aforementioned description includes the effects of ψ explicitly. Variability in xylem properties along the flow path is explored analytically using novel approaches borrowed from `super-statistics' and numerical simulations. The numerical simulations intend to single out which xylem network property is significant in describing the VC shape. The model results corroborate previous research (experimental and 3-dimensional high-resolution simulations) on the effect of vessel size and network topology. It is shown that (i) initial embolism locations alter air-seeding pressure and VC slope; (ii) redundancy and size variations decrease bubble propagation probability with decreasing ψ; and (iii) varying network properties spatially along the flow path delays total loss of conductance. The implications of these findings to linking VC shape to plant traits and the on-going debate about `r' vs `s' shape VCs are highlighted.

  9. A reactive transport model for Marcellus shale weathering

    NASA Astrophysics Data System (ADS)

    Heidari, Peyman; Li, Li; Jin, Lixin; Williams, Jennifer Z.; Brantley, Susan L.

    2017-11-01

    Shale formations account for 25% of the land surface globally and contribute a large proportion of the natural gas used in the United States. One of the most productive shale-gas formations is the Marcellus, a black shale that is rich in organic matter and pyrite. As a first step toward understanding how Marcellus shale interacts with water in the surface or deep subsurface, we developed a reactive transport model to simulate shale weathering under ambient temperature and pressure conditions, constrained by soil and water chemistry data. The simulation was carried out for 10,000 years since deglaciation, assuming bedrock weathering and soil genesis began after the last glacial maximum. Results indicate weathering was initiated by pyrite dissolution for the first 1000 years, leading to low pH and enhanced dissolution of chlorite and precipitation of iron hydroxides. After pyrite depletion, chlorite dissolved slowly, primarily facilitated by the presence of CO2 and organic acids, forming vermiculite as a secondary mineral. A sensitivity analysis indicated that the most important controls on weathering include the presence of reactive gases (CO2 and O2), specific surface area, and flow velocity of infiltrating meteoric water. The soil chemistry and mineralogy data could not be reproduced without including the reactive gases. For example, pyrite remained in the soil even after 10,000 years if O2 was not continuously present in the soil column; likewise, chlorite remained abundant and porosity remained small if CO2 was not present in the soil gas. The field observations were only simulated successfully when the modeled specific surface areas of the reactive minerals were 1-3 orders of magnitude smaller than surface area values measured for powdered minerals. Small surface areas could be consistent with the lack of accessibility of some fluids to mineral surfaces due to surface coatings. In addition, some mineral surface is likely interacting only with equilibrated pore fluids. An increase in the water infiltration rate enhanced weathering by removing dissolution products and maintaining far-from-equilibrium conditions. We conclude from these observations that availability of reactive surface area and transport of H2O and gases are the most important factors affecting rates of Marcellus shale weathering of the in the shallow subsurface. This weathering study documents the utility of reactive transport modeling for complex subsurface processes. Such modelling could be extended to understand interactions between injected fluids and Marcellus shale gas reservoirs at higher temperature, pressure, and salinity conditions.

  10. Using Zebrafish to Study Podocyte Genesis During Kidney Development and Regeneration

    PubMed Central

    Kroeger, Paul T.; Wingert, Rebecca A.

    2014-01-01

    SUMMARY During development, vertebrates form a progression of up to three different kidneys that are comprised of functional units termed nephrons. Nephron composition is highly conserved across species, and an increasing appreciation of the similarities between zebrafish and mammalian nephron cell types has positioned the zebrafish as a relevant genetic system for nephrogenesis studies. A key component of the nephron blood filter is a specialized epithelial cell known as the podocyte. Podocyte research is of the utmost importance as a vast majority of renal diseases initiate with the dysfunction or loss of podocytes, resulting in a condition known as proteinuria that causes nephron degeneration and eventually leads to kidney failure. Understanding how podocytes develop during organogenesis may elucidate new ways to promote nephron health by stimulating podocyte replacement in kidney disease patients. In this review, we discuss how the zebrafish model can be used to study kidney development, and how zebrafish research has provided new insights into podocyte lineage specification and differentiation. Further, we discuss the recent discovery of podocyte regeneration in adult zebrafish, and explore how continued basic research using zebrafish can provide important knowledge about podocyte genesis in embryonic and adult environments. PMID:24920186

  11. Super-deep diamond genesis at Redox conditions of slab-mantle boundary

    NASA Astrophysics Data System (ADS)

    Gao, J.; Chen, B.; Wu, X.

    2017-12-01

    Diamond genesis is an intriguing issue for diamond resources and the deep carbon cycle of the Earth's interiors. Super-deep diamonds, representing only 6% of the global diamond population, often host inclusions with phase assemblages requiring a sublithospheric origin (>300 km). Being the windows for probing the deep Earth, super-deep diamonds with their distinctive micro-inclusions not only record a history of oceanic lithosphere subduction and upward transport at a depth of >250 km to even 1000 km, but indicate their genesis pertinent to mantle-carbonate melts in a Fe0-bufferred reduced condition. Our pilot experiments have evidenced the formation of diamonds from MgCO3-Fe0 system in a diamond anvil cell device at 25 GPa and 1800 K. Detailed experimental investigations of redox mechanism of MgCO3-Fe0 and CaCO3-Fe0 coupling have been conducted using multi-anvil apparatus. The conditions are set along the oceanic lithosphere subduction paths in the pressure-temperature range of 10-24 GPa and 1200-2000 K, covering the formation region of most super-deep diamonds. The clear reaction zones strongly support the redox reaction between carbonatitic slab and Fe0-bearing metals under mantle conditions. Our study has experimentally documented the possibility of super-deep diamond genesis at redox conditions of carbonateitic slab and Fe0-bearings. The kinetics of diamond formation as a function of pressure-temperature conditions are also discussed.

  12. Computing volume potentials for noninvasive imaging of cardiac excitation.

    PubMed

    van der Graaf, A W Maurits; Bhagirath, Pranav; van Driel, Vincent J H M; Ramanna, Hemanth; de Hooge, Jacques; de Groot, Natasja M S; Götte, Marco J W

    2015-03-01

    In noninvasive imaging of cardiac excitation, the use of body surface potentials (BSP) rather than body volume potentials (BVP) has been favored due to enhanced computational efficiency and reduced modeling effort. Nowadays, increased computational power and the availability of open source software enable the calculation of BVP for clinical purposes. In order to illustrate the possible advantages of this approach, the explanatory power of BVP is investigated using a rectangular tank filled with an electrolytic conductor and a patient specific three dimensional model. MRI images of the tank and of a patient were obtained in three orthogonal directions using a turbo spin echo MRI sequence. MRI images were segmented in three dimensional using custom written software. Gmsh software was used for mesh generation. BVP were computed using a transfer matrix and FEniCS software. The solution for 240,000 nodes, corresponding to a resolution of 5 mm throughout the thorax volume, was computed in 3 minutes. The tank experiment revealed that an increased electrode surface renders the position of the 4 V equipotential plane insensitive to mesh cell size and reduces simulated deviations. In the patient-specific model, the impact of assigning a different conductivity to lung tissue on the distribution of volume potentials could be visualized. Generation of high quality volume meshes and computation of BVP with a resolution of 5 mm is feasible using generally available software and hardware. Estimation of BVP may lead to an improved understanding of the genesis of BSP and sources of local inaccuracies. © 2014 Wiley Periodicals, Inc.

  13. Optimization Studies of the FERMI at ELETTRA FEL Design

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    De Ninno, Giovanni; Fawley, William M.; Penn, Gregory E.

    The FERMI at ELETTRA project at Sincotrone Trieste involves two FEL's, each based upon the principle of seeded harmonic generation and using the existing ELETTRA injection linac at 1.2 GeV beam energy. Scheduled to be completed in 2008, FEL-1 will operate in 40-100 nm wavelength range and will involve one stage of harmonic up-conversion. The second undulator line, FEL-2, will begin operation two years later in the 10-40 nm wavelength range and use two harmonic stages operating as a cascade. The FEL design assumes continuous wavelength tunability over the full wavelength range, and polarization tunability of the output radiation includingmore » vertical or horizontal linear as well as helical polarization. The design considers focusing properties and segmentation of realizable undulators and available input seed lasers. We review the studies that have led to our current design. We present results of simulations using GENESIS and GINGER simulation codes including studies of various shot-to-shot fluctuations and undulator errors. Findings for the expected output radiation in terms of the power, transverse and longitudinal coherence are reported.« less

  14. The ferroan-anorthositic suite and the extent of primordial lunar melting

    NASA Technical Reports Server (NTRS)

    Warren, Paul H.; Kallemeyn, Gregory W.

    1992-01-01

    The Apollo highlands rock collection includes more than 100 'pristine' fragments that survived the intense meteoritic bombardment of the ancient lunar crust with unmixed, endogenously igneous compositions. The geochemical anomaly manifested by the 'ferroan-anorthositic suite' (FAS) appears to reflect a geochemical, and probably also a genetic, bimodality among the ancient lunar cumulates. Early models that purported to account for this bimodality as a product of a single magma have been discredited. The model of the present paper implies that the Mg-suite rocks formed by a comparatively normal variety of basaltic fractional crystallization (FC) shortly after the era of magma ocean (MO) crystallization and FAS genesis.

  15. Recent Optical and SEM Characterization of Genesis Solar Wind Concentrator Diamond on Silicon Collector

    NASA Technical Reports Server (NTRS)

    Allton, Judith H.; Rodriquez, M. C.; Burkett, P. J.; Ross, D. K.; Gonzalez, C. P.; McNamara, K. M.

    2013-01-01

    One of the 4 Genesis solar wind concentrator collectors was a silicon substrate coated with diamond-like carbon (DLC) in which to capture solar wind. This material was designed for analysis of solar nitrogen and noble gases [1, 2]. This particular collector fractured during landing, but about 80% of the surface was recovered, including a large piece which was subdivided in 2012 [3, 4, 5]. The optical and SEM imaging and analysis described below supports the subdivision and allocation of the diamond-on-silicon (DOS) concentrator collector.

  16. Uncertainty analysis of diffuse-gray radiation enclosure problems: A hypersensitive case study

    NASA Technical Reports Server (NTRS)

    Taylor, Robert P.; Luck, Rogelio; Hodge, B. K.; Steele, W. Glenn

    1993-01-01

    An uncertainty analysis of diffuse-gray enclosure problems is presented. The genesis was a diffuse-gray enclosure problem which proved to be hypersensitive to the specification of view factors. This genesis is discussed in some detail. The uncertainty analysis is presented for the general diffuse-gray enclosure problem and applied to the hypersensitive case study. It was found that the hypersensitivity could be greatly reduced by enforcing both closure and reciprocity for the view factors. The effects of uncertainties in the surface emissivities and temperatures are also investigated.

  17. Higher Magnification Imaging of the Polished Aluminum Collector Returned from the Genesis Mission

    NASA Technical Reports Server (NTRS)

    Rodriquez, Melissa C.; Burkett, P. J.; Allton, J. H.

    2011-01-01

    The polished aluminum collector (previously referred to as the polished aluminum kidney) was intended for noble gas analysis for the Gene-sis mission. The aluminum collector, fabricated from alloy 6061T, was polished for flight with alumina, then diamond paste. Final cleaning was performed by soak-ing and rinsing with hexane, then isopropanol, and last-ly megasonically energized ultrapure water prior to installation. It was mounted inside the collector canister on the thermal shield at JSC in 2000. The polished aluminum collector was not surveyed microscopically prior to flight.

  18. Electrical characteristics of simulated tornadoes

    NASA Astrophysics Data System (ADS)

    Zimmerman, M. I.; Farrell, W. M.; Barth, E. L.; Lewellen, D. C.; Lewellen, W. S.; Perlongo, N. J.; Jackson, T.

    2012-12-01

    It is well known that tornadoes and dust devils have the ability to accumulate significant, visible clouds of debris. Collisions between sand-like debris species produce different electric charges on different types of grains, which convect along different trajectories around the vortex. Thus, significant charge separations and electric currents are possible, which as the vortex fluctuates over time are thought to produce ULF radiation signatures that have been measured in the field. These electric and magnetic fields may contain valuable information about tornado structure and genesis, and may be critical in driving electrochemical processes within dust devils on Mars. In the present work, existing large eddy simulations of debris-laden tornadoes performed at West Virginia University are coupled with a new debris-charging and advection code developed at Goddard Space Flight Center to investigate the detailed (meter-resolution) fluid-dynamic origins of electromagnetic fields within terrestrial vortices. First results are presented, including simulations of the electric and magnetic fields that would be observed by a near-surface, instrument-laden probe during a direct encounter with a tornado. This research was supported by an appointment to the NASA Postdoctoral Program at the Goddard Space Flight Center, administered by Oak Ridge Associated Universities through a contract with NASA. The generous allocation of computing resources by Dr. Timothy J. Stubbs is gratefully acknowledged.

  19. New results on the hydrodynamic behaviour of fossil Nummulites tests from two nummulite banks from the Bartonian and Priabonian of northern Italy

    PubMed Central

    Seddighi, Mona; Briguglio, Antonino; Hohenegger, Johann; Papazzoni, Cesare Andrea

    2015-01-01

    Settling velocities of 58 well-preserved tests of fossil Nummulites were experimentally determined using a settling tube. The tests were collected from the nummulite banks of Pederiva di Grancona (A forms of N. lyelli and N. striatus, Middle Eocene) and San Germano dei Berici (A and B forms of N. fabianii, Late Eocene), both in the Berici Mts. (Veneto, northern Italy). The data were compared with estimated settling velocities that the same specimens might have had in life conditions. This was done by reconstructing their densities simulating water-filled condition and, to simulate post-diagenetic effects, under calcite-filled condition. These simulations show that A and B forms, even if they greatly diverge in shape, volume and size, still possess comparable settling velocities, and that each nummulite bank is characterized by specific hydrodynamic parameters. The use of settling velocity as a parameter to quantify the hydrodynamic behaviour of particles in seawater enables estimation of palaeoenvironmental conditions such as depth, substrate and the energy scenario. Such information is useful in obtaining further insights into the genesis of nummulite banks, the autochthony or allochthony of which is still being debated. Our results point to an autochthonous interpretation. PMID:26681827

  20. New results on the hydrodynamic behaviour of fossil Nummulites tests from two nummulite banks from the Bartonian and Priabonian of northern Italy.

    PubMed

    Seddighi, Mona; Briguglio, Antonino; Hohenegger, Johann; Papazzoni, Cesare Andrea

    2015-09-01

    Settling velocities of 58 well-preserved tests of fossil Nummulites were experimentally determined using a settling tube. The tests were collected from the nummulite banks of Pederiva di Grancona (A forms of N. lyelli and N. striatus, Middle Eocene) and San Germano dei Berici (A and B forms of N. fabianii, Late Eocene), both in the Berici Mts. (Veneto, northern Italy). The data were compared with estimated settling velocities that the same specimens might have had in life conditions. This was done by reconstructing their densities simulating water-filled condition and, to simulate post-diagenetic effects, under calcite-filled condition. These simulations show that A and B forms, even if they greatly diverge in shape, volume and size, still possess comparable settling velocities, and that each nummulite bank is characterized by specific hydrodynamic parameters. The use of settling velocity as a parameter to quantify the hydrodynamic behaviour of particles in seawater enables estimation of palaeoenvironmental conditions such as depth, substrate and the energy scenario. Such information is useful in obtaining further insights into the genesis of nummulite banks, the autochthony or allochthony of which is still being debated. Our results point to an autochthonous interpretation.

  1. Tempo of magma degassing and the genesis of porphyry copper deposits.

    PubMed

    Chelle-Michou, Cyril; Rottier, Bertrand; Caricchi, Luca; Simpson, Guy

    2017-01-12

    Porphyry deposits are copper-rich orebodies formed by precipitation of metal sulphides from hydrothermal fluids released from magmatic intrusions that cooled at depth within the Earth's crust. Finding new porphyry deposits is essential because they are our largest source of copper and they also contain other strategic metals including gold and molybdenum. However, the discovery of giant porphyry deposits is hindered by a lack of understanding of the factors governing their size. Here, we use thermal modelling and statistical simulations to quantify the tempo and the chemistry of fluids released from cooling magmatic systems. We confirm that typical arc magmas produce fluids similar in composition to those that form porphyry deposits and conclude that the volume and duration of magmatic activity exert a first order control on the endowment (total mass of deposited copper) of economic porphyry copper deposits. Therefore, initial magma enrichment in copper and sulphur, although adding to the metallogenic potential, is not necessary to form a giant deposit. Our results link the respective durations of magmatic and hydrothermal activity from well-known large to supergiant deposits to their metal endowment. This novel approach can readily be implemented as an additional exploration tool that can help assess the economic potential of magmatic-hydrothermal systems.

  2. Tempo of magma degassing and the genesis of porphyry copper deposits

    PubMed Central

    Chelle-Michou, Cyril; Rottier, Bertrand; Caricchi, Luca; Simpson, Guy

    2017-01-01

    Porphyry deposits are copper-rich orebodies formed by precipitation of metal sulphides from hydrothermal fluids released from magmatic intrusions that cooled at depth within the Earth’s crust. Finding new porphyry deposits is essential because they are our largest source of copper and they also contain other strategic metals including gold and molybdenum. However, the discovery of giant porphyry deposits is hindered by a lack of understanding of the factors governing their size. Here, we use thermal modelling and statistical simulations to quantify the tempo and the chemistry of fluids released from cooling magmatic systems. We confirm that typical arc magmas produce fluids similar in composition to those that form porphyry deposits and conclude that the volume and duration of magmatic activity exert a first order control on the endowment (total mass of deposited copper) of economic porphyry copper deposits. Therefore, initial magma enrichment in copper and sulphur, although adding to the metallogenic potential, is not necessary to form a giant deposit. Our results link the respective durations of magmatic and hydrothermal activity from well-known large to supergiant deposits to their metal endowment. This novel approach can readily be implemented as an additional exploration tool that can help assess the economic potential of magmatic-hydrothermal systems. PMID:28079160

  3. Harmonic cascade FEL designs for LUX

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Penn, G.; Reinsch, M.; Wurtele, J.

    LUX is a design concept for an ultrafast X-ray science facility, based on an electron beam accelerated to GeV energies in are circulating linac. Included in the design are short duration (200 fs or shorter FWHM) light sources using multiple stages of higher harmonic generation, seeded by a 200-250 nm laser of similar duration. This laser modulates the energy of a group of electrons within the electron bunch; this section of the electron bunch then produces radiation at a higher harmonic after entering a second, differently tuned undulator. Repeated stages in a cascade yield increasing photon energies up to 1more » keV. Most of the undulators in the cascade operate in the low-gain FEL regime. Harmonic cascades have been designed for each pass of the recirculating linac up to a final electron beam energy of 3.1 GeV. For a given cascade, the photon energy can be selected over a wide range by varying the seed laser frequency and the field strength in the undulators. We present simulation results using the codes GENESIS and GINGER, as well as the results of analytical models which predict FEL performance. We discuss lattice considerations pertinent for harmonic cascade FELs, as well as sensitivity studies and requirements on the electron beam.« less

  4. The Psycho-Neurology of Cross-Species Affective/Social Neuroscience: Understanding Animal Affective States as a Guide to Development of Novel Psychiatric Treatments.

    PubMed

    Panksepp, Jaak

    During the past half century of research with preclinical animal models, affective neuroscience has helped identify and illuminate the functional neuroanatomies and neurochemistries of seven primary process, i.e., genetically provided emotional systems of mammalian brains. All are subcortically localized, allowing animal models to guide the needed behavioral and neuroscientific analyses at levels of detail that cannot be achieved through human research, including modern brain imaging. They consist of the following neuronal processes: SEEKING/Enthusiasm, RAGE/Anger, FEAR/Anxiety, sexual LUST/Passion, maternal CARE/Nurturance, separation-distress PANIC/Grief and PLAY/Social Joy. Several of these systems figure heavily in social bonding. I will focus here especially on the genesis of depression. Its genesis is significantly influenced by (i) sustained overactivity of the separation-distress PANIC system reflecting severed social bonds and the excessive "psychological pain" of loneliness that can, if sustained, lead to a downward cascade known as psychological despair, and (ii) the despair phase that follows the acute PANIC response, which is characterized by abnormally low activity of the SEEKING, the so-called brain reward networks, leading to amotivational states that characterize depression. Depressive affect is promoted by such brain affective mechanisms of social attachments and social loss as well as diminished arousability of the SEEKING system, leading to chronic dysphoria. To understand why depression feels so bad, we must understand the neural mechanisms that mediate such social feelings.

  5. Quantification of a greenhouse hydrologic cycle from equatorial to polar latitudes: The mid-Cretaceous water bearer revisited

    USGS Publications Warehouse

    Suarez, M.B.; Gonzalez, Luis A.; Ludvigson, Greg A.

    2011-01-01

    This study aims to investigate the global hydrologic cycle during the mid-Cretaceous greenhouse by utilizing the oxygen isotopic composition of pedogenic carbonates (calcite and siderite) as proxies for the oxygen isotopic composition of precipitation. The data set builds on the Aptian-Albian sphaerosiderite ??18O data set presented by Ufnar et al. (2002) by incorporating additional low latitude data including pedogenic and early meteoric diagenetic calcite ??18O. Ufnar et al. (2002) used the proxy data derived from the North American Cretaceous Western Interior Basin (KWIB) in a mass balance model to estimate precipitation-evaporation fluxes. We have revised this mass balance model to handle sphaerosiderite and calcite proxies, and to account for longitudinal travel by tropical air masses. We use empirical and general circulation model (GCM) temperature gradients for the mid-Cretaceous, and the empirically derived ??18O composition of groundwater as constraints in our mass balance model. Precipitation flux, evaporation flux, relative humidity, seawater composition, and continental feedback are adjusted to generate model calculated groundwater ??18O compositions (proxy for precipitation ??18O) that match the empirically-derived groundwater ??18O compositions to within ??0.5???. The model is calibrated against modern precipitation data sets.Four different Cretaceous temperature estimates were used: the leaf physiognomy estimates of Wolfe and Upchurch (1987) and Spicer and Corfield (1992), the coolest and warmest Cretaceous estimates compiled by Barron (1983) and model outputs from the GENESIS-MOM GCM by Zhou et al. (2008). Precipitation and evaporation fluxes for all the Cretaceous temperature gradients utilized in the model are greater than modern precipitation and evaporation fluxes. Balancing the model also requires relative humidity in the subtropical dry belt to be significantly reduced. As expected calculated precipitation rates are all greater than modern precipitation rates. Calculated global average precipitation rates range from 371mm/year to 1196mm/year greater than modern precipitation rates. Model results support the hypothesis that increased rainout produces ??18O-depleted precipitation.Sensitivity testing of the model indicates that the amount of water vapor in the air mass, and its origin and pathway, significantly affect the oxygen isotopic composition of precipitation. Precipitation ??18O is also sensitive to seawater ??18O and enriched tropical seawater was necessary to simulate proxy data (consistent with fossil and geologic evidence for a warmer and evaporatively enriched Tethys). Improved constraints in variables such as seawater ??18O can help improve boundary conditions for mid-Cretaceous climate simulations. ?? 2011 Elsevier B.V.

  6. Dynamic rupture models of subduction zone earthquakes with off-fault plasticity

    NASA Astrophysics Data System (ADS)

    Wollherr, S.; van Zelst, I.; Gabriel, A. A.; van Dinther, Y.; Madden, E. H.; Ulrich, T.

    2017-12-01

    Modeling tsunami-genesis based on purely elastic seafloor displacement typically underpredicts tsunami sizes. Dynamic rupture simulations allow to analyse whether plastic energy dissipation is a missing rheological component by capturing the complex interplay of the rupture front, emitted seismic waves and the free surface in the accretionary prism. Strike-slip models with off-fault plasticity suggest decreasing rupture speed and extensive plastic yielding mainly at shallow depths. For simplified subduction geometries inelastic deformation on the verge of Coulomb failure may enhance vertical displacement, which in turn favors the generation of large tsunamis (Ma, 2012). However, constraining appropriate initial conditions in terms of fault geometry, initial fault stress and strength remains challenging. Here, we present dynamic rupture models of subduction zones constrained by long-term seismo-thermo-mechanical modeling (STM) without any a priori assumption of regions of failure. The STM model provides self-consistent slab geometries, as well as stress and strength initial conditions which evolve in response to tectonic stresses, temperature, gravity, plasticity and pressure (van Dinther et al. 2013). Coseismic slip and coupled seismic wave propagation is modelled using the software package SeisSol (www.seissol.org), suited for complex fault zone structures and topography/bathymetry. SeisSol allows for local time-stepping, which drastically reduces the time-to-solution (Uphoff et al., 2017). This is particularly important in large-scale scenarios resolving small-scale features, such as the shallow angle between the megathrust fault and the free surface. Our dynamic rupture model uses a Drucker-Prager plastic yield criterion and accounts for thermal pressurization around the fault mimicking the effect of pore pressure changes due to frictional heating. We first analyze the influence of this rheology on rupture dynamics and tsunamigenic properties, i.e. seafloor displacement, in 2D. Finally, we use the same rheology in a large-scale 3D scenario of the 2004 Sumatra earthquake to shed light to the source process that caused the subsequent devastating tsunami.

  7. Dune formation on the Cooper Creek floodplain, Strzelecki Desert, Australia - first results of morphodynamic simulations

    NASA Astrophysics Data System (ADS)

    Kryger, Mateusz; Bubenzer, Olaf; Parteli, Eric

    2017-04-01

    Linear Dunes, which align longitudinally to the resultant wind vector, are the prevailing type of the south-north trending and partially vegetated dunes in the Strzelecki Desert, Australia. However, particularly on the Cooper Creek floodplain near Innamincka, striking complex dune features consisting of transversely oriented east-west trending dunes occur. These transverse dunes extend over several kilometers and are superimposed by linear dunes that elongate northwards and are separated by sandy swales. The aeolian features in the Strzelecki Desert are the result of interrelated late quaternary aeolian and fluvial activity and serve, thus, as archives providing information about variations in palaeoclimate and potential changes in fluvial sediment supply and wind strength and directionality. However, since the dunes are currently mostly stabilized by vegetation, it is uncertain whether their formation can be explained by the contemporary wind systems. To understand the dynamic processes underlying the genesis of the dune field in the Strzelecki Desert, the role of vegetation and the wind regimes leading to the observed dune patterns must be elucidated. Here we investigate the formative processes of the dune features occurring on the Cooper Creek floodplain by means of morphodynamic modeling of aeolian sand transport and dune formation in presence of vegetation growth. Our simulations show that a source-bordering dune can be formed out of the sediments of seasonally exposed sandbars of the palaeo-Cooper system by a unidirectional wind, which explains the emergence of the transverse dunes in the field. Moreover, a shift in the wind regime to obtuse bidirectional wind flows combined with a rapid decrease in the vegetation cover leads to the formation of linear dunes on the surface and in the lee of the transverse dunes. These linear dunes elongate over several kilometers downwind as a result of the seasonal wind changes. The dune shapes obtained in our simulations agree well with the real dune morphologies when a low vegetation growth rate is applied in the model. Although geochronological investigations, reported in the literature, on the Cooper Creek floodplain did not show the linear dunes declining in age downwind (which suggests the adjacent swales or the transverse dune to be the sediment source), our simulations show that strikingly similar linear dune morphologies can be obtained by sediment influx due to saltation alone. In this case, the bars of the palaeo-Cooper system might as well have served as the sediment source for the formation of the linear dunes. Therefore, our results suggest that a long-distance transport extension model could also explain the linear dune formation, while previous geochronological investigations supported the wind-rift vertical extension and wind-rift vertical accretion models. The morphodynamic simulations may thus not only help to reconstruct the palaeoenvironment of the northern Strzelecki Desert, but also provide insights for the interpretation of the sediment archives located on the Cooper Creek alluvial fan.

  8. The role of the Na+/Ca2+ exchanger, INa and ICaL in the genesis of dofetilide-induced torsades de pointes in isolated, AV-blocked rabbit hearts

    PubMed Central

    Farkas, Attila S; Makra, Péter; Csík, Norbert; Orosz, Szabolcs; Shattock, Michael J; Fülöp, Ferenc; Forster, Tamás; Csanády, Miklós; Papp, Julius Gy; Varró, András; Farkas, András

    2009-01-01

    Background and purpose: The Na+/Ca2+ exchanger (NCX) may contribute to triggered activity and transmural dispersion of repolarization, which are substrates of torsades de pointes (TdP) type arrhythmias. This study examined the effects of selective inhibition of the NCX by SEA0400 on the occurrence of dofetilide-induced TdP. Experimental approach: Effects of SEA0400 (1 µmol·L−1) on dofetilide-induced TdP was studied in isolated, Langendorff-perfused, atrioventricular (AV)-blocked rabbit hearts. To verify the relevance of the model, lidocaine (30 µmol·L−1) and verapamil (750 nmol·L−1) were also tested against dofetilide-induced TdP. Key results: Acute AV block caused a chaotic idioventricular rhythm and strikingly increased beat-to-beat variability of the RR and QT intervals. SEA0400 exaggerated the dofetilide-induced increase in the heart rate-corrected QT interval (QTc) and did not reduce the incidence of dofetilide-induced TdP [100% in the SEA0400 + dofetilide group vs. 75% in the dofetilide (100 nmol·L−1) control]. In the second set of experiments, verapamil further increased the dofetilide-induced QTc prolongation and neither verapamil nor lidocaine reduced the dofetilide-induced increase in the beat-to-beat variability of the QT interval. However, lidocaine decreased and verapamil prevented the development of dofetilide-induced TdP as compared with the dofetilide control (TdP incidence: 13%, 0% and 88% respectively). Conclusions and implications: Na+/Ca2+ exchanger does not contribute to dofetilide-induced TdP, whereas Na+ and Ca2+ channel activity is involved in TdP genesis in isolated, AV-blocked rabbit hearts. Neither QTc prolongation nor an increase in the beat-to-beat variability of the QT interval is a sufficient prerequisite of TdP genesis in rabbit hearts. PMID:19222480

  9. High Resolution Modelling of Crop Response to Climate Change

    NASA Astrophysics Data System (ADS)

    Mirmasoudi, S. S.; Byrne, J. M.; MacDonald, R. J.; Lewis, D.

    2014-12-01

    Crop production is one of the most vulnerable sectors to climatic variability and change. Increasing atmospheric CO2 concentration and other greenhouse gases are causing increases in global temperature. In western North America, water supply is largely derived from mountain snowmelt. Climate change will have a significant impact on mountain snowpack and subsequently, the snow-derived water supply. This will strain water supplies and increase water demand in areas with substantial irrigation agriculture. Increasing temperatures may create heat stress for some crops regardless of soil water supply, and increasing surface O3 and other pollutants may damage crops and ecosystems. CO2 fertilization may or may not be an advantage in future. This work is part of a larger study that will address a series of questions based on a range of future climate scenarios for several watersheds in western North America. The key questions are: (1) how will snowmelt and rainfall runoff vary in future; (2) how will seasonal and inter-annual soil water supply vary, and how might that impacts food supplies; (3) how might heat stress impact (some) crops even with adequate soil water; (4) will CO2 fertilization alter crop yields; and (5) will pollution loads, particularly O3, cause meaningful changes to crop yields? The Generate Earth Systems Science (GENESYS) Spatial Hydrometeorological Model is an innovative, efficient, high-resolution model designed to assess climate driven changes in mountain snowpack derived water supplies. We will link GENESYS to the CROPWAT crop model system to assess climate driven changes in water requirement and associated crop productivity for a range of future climate scenarios. Literature bases studies will be utilised to develop approximate crop response functions for heat stress, CO2 fertilization and for O3 damages. The overall objective is to create modeling systems that allows meaningful assessment of agricultural productivity at a watershed scale under a range of climate scenarios.

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    San Yuk, V.I.

    Not widely known facts on the genesis of the Skyrme model are presented in a historical survey, based on Skyrme's earliest papers and on his own published remembrance. This paper considers the evolution of Skyrme's model description of nuclear matter from the Mesonic Fluid model up to its final version, known as the baryon model. We pay special tribute to some well-known ideas in contemporary particle physics which one can find in Skyrme's earlier papers, such as: Nuclear Democracy, the Solitonic Mechanism, the Nonlinear Realization of Chiral Symmetry, Topological Charges, Fermi-Bose Transmutations, etc. It is curious to note in themore » final version of the Skyrme model gleams of Kelvin's Vortex Atoms theory. In conclusion we make a brief analysis of the validity of Skyrme's conjectures in view of recent results and pinpoint some questions which still remain.« less

  11. Collagen IV and basement membrane at the evolutionary dawn of metazoan tissues

    PubMed Central

    Fidler, Aaron L; Darris, Carl E; Chetyrkin, Sergei V; Pedchenko, Vadim K; Boudko, Sergei P; Brown, Kyle L; Gray Jerome, W; Hudson, Julie K; Rokas, Antonis; Hudson, Billy G

    2017-01-01

    The role of the cellular microenvironment in enabling metazoan tissue genesis remains obscure. Ctenophora has recently emerged as one of the earliest-branching extant animal phyla, providing a unique opportunity to explore the evolutionary role of the cellular microenvironment in tissue genesis. Here, we characterized the extracellular matrix (ECM), with a focus on collagen IV and its variant, spongin short-chain collagens, of non-bilaterian animal phyla. We identified basement membrane (BM) and collagen IV in Ctenophora, and show that the structural and genomic features of collagen IV are homologous to those of non-bilaterian animal phyla and Bilateria. Yet, ctenophore features are more diverse and distinct, expressing up to twenty genes compared to six in vertebrates. Moreover, collagen IV is absent in unicellular sister-groups. Collectively, we conclude that collagen IV and its variant, spongin, are primordial components of the extracellular microenvironment, and as a component of BM, collagen IV enabled the assembly of a fundamental architectural unit for multicellular tissue genesis. DOI: http://dx.doi.org/10.7554/eLife.24176.001 PMID:28418331

  12. Interdecadal Change of Tropical Cyclone Genesis Controlling Parameter in Western North Pacific

    NASA Astrophysics Data System (ADS)

    Li, T.

    2017-12-01

    The main environmental parameter controlling tropical cyclone (TC) genesis in the western North Pacific (WNP) changed in different interdecadal periods. The interannual variability of TC genesis frequency was primarily control by specific humidity in 1950-1976, sea surface temperature (SST) in 1977-1998, and vorticity in 1999-2014. A further diagnosis shows that the change of environmental specific humidity during 1950-1976 was attributed to anomalous advection of mean moisture during ENSO developing summer. The SST change during 1977-1998 was associated with circulation change during ENSO decaying summer. The change of environment vorticity was primarily related to CP-type El Niño during 1999-2014. The ultimate cause of the controlling parameter change is attributed to the change of ENSO behavior. Compared to the first period, a stronger EP-type ENSO variability in the second period leads to a stronger circulation/SST response during ENSO decaying phase. The occurrence of more frequent CP type El Niño in the third period was responsible for greater vorticity controlling in the WNP.

  13. Enhanced Cleaning of Genesis Solar Wind Sample 61348 for Film Residue Removal

    NASA Technical Reports Server (NTRS)

    Allums, K. K.; Gonzalez, C. P.; Kuhlman, K. R.; Allton, J. H.

    2015-01-01

    The Genesis mission returned to Earth on September 8, 2004, experiencing a nonnominal reentry. During the recovery of the collector materials from the capsule, many of the collector fragments were placed on the adhesive protion of post-it notes to prevent the fragments from moving during transport back to Johnson Space Center. This unknowingly provided an additional contaminate that would prove difficult to remove with the limited chemistries allowed in the Genesis Curation Laboratory. Generally when collector material samples are prepared for allocation to PIs, the samples are cleaned front side only with Ultra-Pure Water (UPW) via megasonic dispersion to the collector surface to remove crash debris and contamination. While this cleaning method works well on samples that were not placed on post-its during recovery, it has caused movement of the residue on the back of the sample to be deposited on the front in at least two examples. Therefore, samples placed on the adhesive portion on post-it note, require enhanced cleaning methods since post-it residue has proved resistant to UPW cleaning.

  14. Effect of an angular trajectory kick in a high-gain free-electron laser

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baxevanis, Panagiotis; Huang, Zhirong; Stupakov, Gennady

    In a free-electron laser, a transverse momentum offset (or “kick”) results in an oscillation of the centroid of the electron beam about the undulator axis. Studying the influence of this effect on the free-electron laser (FEL) interaction is important both from a tolerance point of view and for its potential diagnostic applications. In this paper, we present a self-consistent theoretical analysis of a high-gain FEL driven by such a “kicked” beam. In particular, we derive a solution to the three-dimensional, linearized initial value problem of the FEL through an orthogonal expansion technique and also describe a variational method for calculatingmore » the average FEL growth rate. Lastly, our results are benchmarked with genesis simulations and provide a robust theoretical background for a comparison with previous analytical results.« less

  15. Effect of an angular trajectory kick in a high-gain free-electron laser

    DOE PAGES

    Baxevanis, Panagiotis; Huang, Zhirong; Stupakov, Gennady

    2017-04-18

    In a free-electron laser, a transverse momentum offset (or “kick”) results in an oscillation of the centroid of the electron beam about the undulator axis. Studying the influence of this effect on the free-electron laser (FEL) interaction is important both from a tolerance point of view and for its potential diagnostic applications. In this paper, we present a self-consistent theoretical analysis of a high-gain FEL driven by such a “kicked” beam. In particular, we derive a solution to the three-dimensional, linearized initial value problem of the FEL through an orthogonal expansion technique and also describe a variational method for calculatingmore » the average FEL growth rate. Lastly, our results are benchmarked with genesis simulations and provide a robust theoretical background for a comparison with previous analytical results.« less

  16. Process-informed extreme value statistics- Why and how?

    NASA Astrophysics Data System (ADS)

    Schumann, Andreas; Fischer, Svenja

    2017-04-01

    In many parts of the world, annual maximum series (AMS) of runoff consist of flood peaks, which differ in their genesis. There are several aspects why these differences should be considered: Often multivariate flood characteristics (volumes, shapes) are of interest. These characteristics depend on the flood types. For regionalization, the main impacts on the flood regime has to be specified. If this regime depends on different flood types, type-specific hydro-meteorological and/or watershed characteristics are relevant. The ratios between event types often change over the range of observations. If a majority of events, which belongs to certain flood type, dominates the extrapolation of a probability distribution function (pdf), it is a problem if this more frequent type would not be typical for extraordinary large extremes, determining the right tail of the pdf. To consider differences in flood origin, several problems has to be solved. The events have to be separated into different groups according to their genesis. This can be a problem for long past events where e.g. precipitation data are not available. Another problem consists in the flood type-specific statistics. If block maxima are used, the sample of floods belong to a certain type is often incomplete as other events are overlaying smaller events. Some practical useable statistical tools to solve this and other problems are presented in a case study. Seasonal models were developed which differ between winter and summer floods but also between events with long and short timescales. The pdfs of the two groups of summer floods are combined via a new mixing model. The application to German watersheds demonstrates the advantages of the new model, giving specific influence to flood types.

  17. Fischer 344 and Lewis Rat Strains as a Model of Genetic Vulnerability to Drug Addiction

    PubMed Central

    Cadoni, Cristina

    2016-01-01

    Today it is well acknowledged that both nature and nurture play important roles in the genesis of psychopathologies, including drug addiction. Increasing evidence suggests that genetic factors contribute for at least 40–60% of the variation in liability to drug dependence. Human genetic studies suggest that multiple genes of small effect, rather than single genes, contribute to the genesis of behavioral psychopathologies. Therefore, the use of inbred rat strains might provide a valuable tool to identify differences, linked to genotype, important in liability to addiction and related disorders. In this regard, Lewis and Fischer 344 inbred rats have been proposed as a model of genetic vulnerability to drug addiction, given their innate differences in sensitivity to the reinforcing and rewarding effects of drugs of abuse, as well their different responsiveness to stressful stimuli. This review will provide evidence in support of this model for the study of the genetic influence on addiction vulnerability, with particular emphasis on differences in mesolimbic dopamine (DA) transmission, rewarding and emotional function. It will be highlighted that Lewis and Fischer 344 rats differ not only in several indices of DA transmission and adaptive changes following repeated drug exposure, but also in hypothalamic-pituitary-adrenal (HPA) axis responsiveness, influencing not only the ability of the individual to cope with stressful events, but also interfering with rewarding and motivational processes, given the influence of corticosteroids on dopamine neuron functionality. Further differences between the two strains, as impulsivity or anxiousness, might contribute to their different proneness to addiction, and likely these features might be linked to their different DA neurotransmission plasticity. Although differences in other neurotransmitter systems might deserve further investigation, results from the reviewed studies might open new vistas in understanding aberrant deviations in reward and motivational functions. PMID:26903787

  18. Fischer 344 and Lewis Rat Strains as a Model of Genetic Vulnerability to Drug Addiction.

    PubMed

    Cadoni, Cristina

    2016-01-01

    Today it is well acknowledged that both nature and nurture play important roles in the genesis of psychopathologies, including drug addiction. Increasing evidence suggests that genetic factors contribute for at least 40-60% of the variation in liability to drug dependence. Human genetic studies suggest that multiple genes of small effect, rather than single genes, contribute to the genesis of behavioral psychopathologies. Therefore, the use of inbred rat strains might provide a valuable tool to identify differences, linked to genotype, important in liability to addiction and related disorders. In this regard, Lewis and Fischer 344 inbred rats have been proposed as a model of genetic vulnerability to drug addiction, given their innate differences in sensitivity to the reinforcing and rewarding effects of drugs of abuse, as well their different responsiveness to stressful stimuli. This review will provide evidence in support of this model for the study of the genetic influence on addiction vulnerability, with particular emphasis on differences in mesolimbic dopamine (DA) transmission, rewarding and emotional function. It will be highlighted that Lewis and Fischer 344 rats differ not only in several indices of DA transmission and adaptive changes following repeated drug exposure, but also in hypothalamic-pituitary-adrenal (HPA) axis responsiveness, influencing not only the ability of the individual to cope with stressful events, but also interfering with rewarding and motivational processes, given the influence of corticosteroids on dopamine neuron functionality. Further differences between the two strains, as impulsivity or anxiousness, might contribute to their different proneness to addiction, and likely these features might be linked to their different DA neurotransmission plasticity. Although differences in other neurotransmitter systems might deserve further investigation, results from the reviewed studies might open new vistas in understanding aberrant deviations in reward and motivational functions.

  19. Understanding the impact of saharan dust aerosols on tropical cyclones

    NASA Astrophysics Data System (ADS)

    Naeger, Aaron

    Genesis of Tropical Cyclones (TCs) in the main development region for Atlantic hurricanes is tied to convection initiated by African easterly waves (AEWs) during Northern hemisphere summer and fall seasons. The main development region is also impacted by dust aerosols transported from the Sahara. It has been hypothesized that dust aerosols can modulate the development of TCs through aerosol-radiation and aerosol-cloud interaction processes. In this study, we investigate the impact of dust aerosols on TC development using the Weather Research and Forecasting model coupled with chemistry (WRF-Chem). We first develop a technique to constrain the WRF-Chem model with a realistic three-dimensional spatial distribution of dust aerosols. The horizontal distribution of dust is specified using the Moderate Resolution Imaging Spectroradiometer (MODIS) derived aerosol products and output from the Goddard Chemistry Aerosol Radiation and Transport (GOCART) model. The vertical distribution of dust is constrained using the Cloud Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO). We validate our technique through in situ aircraft measurements where both showed aerosol number concentrations from 20-30 cm-3 in the atmosphere for Saharan dust moving over the eastern Atlantic Ocean. Then, we use the satellite data constraint technique to nudge the WRF-Chem aerosol fields throughout the simulation of TC Florence developing over the eastern Atlantic Ocean during September 2006. Three different experiments are conducted where the aerosol-radiation and aerosol-cloud interaction processes are either activated or deactivated in the model while all other model options are identical between the experiments. By comparing the model experiment results, the impact of the aerosol interaction processes on TC development can be understood. The results indicate that dust aerosols can delay or prevent the development of a TC as the minimum sea level pressure of TC Florence was 13 hPa higher when the aerosols interactions were activated as opposed to deactivated in the model.

  20. A model of metastable dynamics during ongoing and evoked cortical activity

    NASA Astrophysics Data System (ADS)

    La Camera, Giancarlo

    The dynamics of simultaneously recorded spike trains in alert animals often evolve through temporal sequences of metastable states. Little is known about the network mechanisms responsible for the genesis of such sequences, or their potential role in neural coding. In the gustatory cortex of alert rates, state sequences can be observed also in the absence of overt sensory stimulation, and thus form the basis of the so-called `ongoing activity'. This activity is characterized by a partial degree of coordination among neurons, sharp transitions among states, and multi-stability of single neurons' firing rates. A recurrent spiking network model with clustered topology can account for both the spontaneous generation of state sequences and the (network-generated) multi-stability. In the model, each network state results from the activation of specific neural clusters with potentiated intra-cluster connections. A mean field solution of the model shows a large number of stable states, each characterized by a subset of simultaneously active clusters. The firing rate in each cluster during ongoing activity depends on the number of active clusters, so that the same neuron can have different firing rates depending on the state of the network. Because of dense intra-cluster connectivity and recurrent inhibition, in finite networks the stable states lose stability due to finite size effects. Simulations of the dynamics show that the model ensemble activity continuously hops among the different states, reproducing the ongoing dynamics observed in the data. Moreover, when probed with external stimuli, the model correctly predicts the quenching of single neuron multi-stability into bi-stability, the reduction of dimensionality of the population activity, the reduction of trial-to-trial variability, and a potential role for metastable states in the anticipation of expected events. Altogether, these results provide a unified mechanistic model of ongoing and evoked cortical dynamics. NSF IIS-1161852, NIDCD K25-DC013557, NIDCD R01-DC010389.

  1. A multiscale active structural model of the arterial wall accounting for smooth muscle dynamics.

    PubMed

    Coccarelli, Alberto; Edwards, David Hughes; Aggarwal, Ankush; Nithiarasu, Perumal; Parthimos, Dimitris

    2018-02-01

    Arterial wall dynamics arise from the synergy of passive mechano-elastic properties of the vascular tissue and the active contractile behaviour of smooth muscle cells (SMCs) that form the media layer of vessels. We have developed a computational framework that incorporates both these components to account for vascular responses to mechanical and pharmacological stimuli. To validate the proposed framework and demonstrate its potential for testing hypotheses on the pathogenesis of vascular disease, we have employed a number of pharmacological probes that modulate the arterial wall contractile machinery by selectively inhibiting a range of intracellular signalling pathways. Experimental probes used on ring segments from the rabbit central ear artery are: phenylephrine, a selective α 1-adrenergic receptor agonist that induces vasoconstriction; cyclopiazonic acid (CPA), a specific inhibitor of sarcoplasmic/endoplasmic reticulum Ca 2+ -ATPase; and ryanodine, a diterpenoid that modulates Ca 2+ release from the sarcoplasmic reticulum. These interventions were able to delineate the role of membrane versus intracellular signalling, previously identified as main factors in smooth muscle contraction and the generation of vessel tone. Each SMC was modelled by a system of nonlinear differential equations that account for intracellular ionic signalling, and in particular Ca 2+ dynamics. Cytosolic Ca 2+ concentrations formed the catalytic input to a cross-bridge kinetics model. Contractile output from these cellular components forms the input to the finite-element model of the arterial rings under isometric conditions that reproduces the experimental conditions. The model does not account for the role of the endothelium, as the nitric oxide production was suppressed by the action of L-NAME, and also due to the absence of shear stress on the arterial ring, as the experimental set-up did not involve flow. Simulations generated by the integrated model closely matched experimental observations qualitatively, as well as quantitatively within a range of physiological parametric values. The model also illustrated how increased intercellular coupling led to smooth muscle coordination and the genesis of vascular tone. © 2018 The Authors.

  2. The problem of genesis and systematic of sedimentary units of hydrocarbon reservoirs

    NASA Astrophysics Data System (ADS)

    Zhilina, E. N.; Chernova, O. S.

    2017-12-01

    The problem of identifying and ranking sedimentation, facies associations and their constituent parts - lithogenetic types of sedimentary rocks was considered. As a basis for paleo-sedimentary modelling, the author has developed a classification for terrigenous natural reservoirs,that for the first time links separate sedimentological units into a single hierarchical system. Hierarchy ranking levels are based on a compilation of global knowledge and experience in sediment geology, sedimentological study and systematization, and data from deep-well coresrepresentingJurassichydrocarbon-bearing formationsof the southeastern margin of the Western Siberian sedimentary basin.

  3. Aviation System Analysis Capability Executive Assistant Design

    NASA Technical Reports Server (NTRS)

    Roberts, Eileen; Villani, James A.; Osman, Mohammed; Godso, David; King, Brent; Ricciardi, Michael

    1998-01-01

    In this technical document, we describe the design developed for the Aviation System Analysis Capability (ASAC) Executive Assistant (EA) Proof of Concept (POC). We describe the genesis and role of the ASAC system, discuss the objectives of the ASAC system and provide an overview of components and models within the ASAC system, and describe the design process and the results of the ASAC EA POC system design. We also describe the evaluation process and results for applicable COTS software. The document has six chapters, a bibliography, three appendices and one attachment.

  4. Workshop on Early Crustal Genesis: Implications from Earth

    NASA Technical Reports Server (NTRS)

    Phinney, W. C. (Compiler)

    1981-01-01

    Ways to foster increased study of the early evolution of the Earth, considering the planet as a whole, were explored and recommendations were made to NASA with the intent of exploring optimal ways for integrating Archean studies with problems of planetary evolution. Major themes addressed include: (1) Archean contribution to constraints for modeling planetary evolution; (2) Archean surface conditions and processes as clues to early planetary history; and (3) Archean evidence for physical, chemical and isotopic transfer processes in early planetary crusts. Ten early crustal evolution problems are outlined.

  5. Aviation System Analysis Capability Executive Assistant Development

    NASA Technical Reports Server (NTRS)

    Roberts, Eileen; Villani, James A.; Anderson, Kevin; Book, Paul

    1999-01-01

    In this technical document, we describe the development of the Aviation System Analysis Capability (ASAC) Executive Assistant (EA) Proof of Concept (POC) and Beta version. We describe the genesis and role of the ASAC system, discuss the objectives of the ASAC system and provide an overview of components and models in the ASAC system, and describe the design process and the results of the ASAC EA POC and Beta system development. We also describe the evaluation process and results for applicable COTS software. The document has seven chapters, a bibliography, and two appendices.

  6. ASAC Executive Assistant Architecture Description Summary

    NASA Technical Reports Server (NTRS)

    Roberts, Eileen; Villani, James A.

    1997-01-01

    In this technical document, we describe the system architecture developed for the Aviation System Analysis Capability (ASAC) Executive Assistant (EA). We describe the genesis and role of the ASAC system, discuss the objectives of the ASAC system and provide an overview of components and models within the ASAC system, discuss our choice for an architecture methodology, the Domain Specific Software Architecture (DSSA), and the DSSA approach to developing a system architecture, and describe the development process and the results of the ASAC EA system architecture. The document has six appendices.

  7. Investigation into the Formation, Structure, and Evolution of an EF4 Tornado in East China Using a High-Resolution Numerical Simulation

    NASA Astrophysics Data System (ADS)

    Yao, Dan; Xue, Haile; Yin, Jinfang; Sun, Jisong; Liang, Xudong; Guo, Jianping

    2018-04-01

    Devastating tornadoes in China have received growing attention in recent years, but little is known about their formation, structure, and evolution on the tornadic scale. Most of these tornadoes develop within the East Asian monsoon regime, in an environment quite different from tornadoes in the U.S. In this study, we used an idealized, highresolution (25-m grid spacing) numerical simulation to investigate the deadly EF4 (Enhanced Fujita scale category 4) tornado that occurred on 23 June 2016 and claimed 99 lives in Yancheng, Jiangsu Province. A tornadic supercell developed in the simulation that had striking similarities to radar observations. The violent tornado in Funing County was reproduced, exceeding EF4 (74 m s-1), consistent with the on-site damage survey. It was accompanied by a funnel cloud that extended to the surface, and exhibited a double-helix vorticity structure. The signal of tornado genesis was found first at the cloud base in the pressure perturbation field, and then developed both upward and downward in terms of maximum vertical velocity overlapping with the intense vertical vorticity centers. The tornado's demise was found to accompany strong downdrafts overlapping with the intense vorticity centers. One of the interesting findings of this work is that a violent surface vortex was able to be generated and maintained, even though the simulation employed a free-slip lower boundary condition. The success of this simulation, despite using an idealized numerical approach, provides a means to investigate more historical tornadoes in China.

  8. Development of Chemical and Mechanical Cleaning Procedures for Genesis Solar Wind Samples

    NASA Technical Reports Server (NTRS)

    Schmeling, M.; Jurewicz, A. J. G.; Gonzalez, C.; Allums, K. K.; Allton, J. H.

    2018-01-01

    The Genesis mission was the only mission returning pristine solar material to Earth since the Apollo program. Unfortunately, the return of the spacecraft on September 8, 2004 resulted in a crash landing shattering the solar wind collectors into smaller fragments and exposing them to desert soil and other debris. Thorough surface cleaning is required for almost all fragments to allow for subsequent analysis of solar wind material embedded within. However, each collector fragment calls for an individual cleaning approach, as contamination not only varies by collector material but also by sample itself.

  9. ToF-SIMS Investigation of the Effectiveness of Acid-Cleaning procedures for Genesis Solar Wind Collectors

    NASA Technical Reports Server (NTRS)

    Goreva, Y. S.; Humanyun, M.; Burnett, D. S.; Jurewicz, A. J.; Gonzalez, C. P.

    2014-01-01

    ToF-SIMS images of Genesis sample surfaces contain an incredible amount of important information, but they also show that the crash-derived surface contamination has many components, presenting a challenge to cleaning. Within the variability, we have shown that there are some samples which appear to be clean to begin with, e.g. 60471, and some are more contaminated. Samples 60493 and 60500 are a part of a focused study of the effectiveness of aqua regia and/or sulfuric acid cleaning of small flight Si implanted with Li-6 using ToF-SIMS.

  10. Large-scale influences on the pre-genesis of tropical cyclone Karl (2010)

    NASA Astrophysics Data System (ADS)

    Griffin, Kyle S.

    The genesis of Tropical Cyclone (TC) Karl (2010) in September 2010 provided a unique opportunity to examine the continuing problem of understanding tropical cyclogenesis. The precursor disturbance to Karl originated from a cluster of showers east of the Windward Islands and was well sampled by ongoing field campaigns, particularly the PRE-Depression Investigation of Cloud-systems in the Tropics (PREDICT), as the targeted disturbance progressed westward. While traditional genesis theories focusing on moisture and mass fields (e.g. top-down showerhead method) can explain the initial spin-up of the disturbance several days prior to its official genesis, additional perspectives are examined in concert with more traditional methods in order to provide a more complete analysis of the synoptic-scale patterns that influenced the pre-Karl disturbance. A surge of westerly winds from northern South America aids the initial spin-up of the pre-Karl disturbance on 8-9 September, leading to the formation of a nearly closed earth-relative circulation. It can be shown that these anomalous westerly winds are tied to the convectively active phase of a convectively coupled Kelvin wave (CCKW). The observed formation of the nearly closed circulation on 10 September is well timed with the passage of this convectively active phase, a relationship that has been shown to hold true in cases of CCKW-TC interactions around the globe. Physically, the CCKW increases deep convection and aids in the generation of low-level relative vorticity on the cyclonic shear side of the low-level westerly wind anomalies, both of which serve to help organize the pre-Karl disturbance. Finally, the passage of the CCKW coincides with an equatorward surge of cold air and southerly winds in the lee of the Andes, triggered by a passing mid-latitude disturbance on 31 August. As the surge passes the equator on 7 September, little temperature perturbation remains with the surge, but terrain-channeled low-level flow acts to turn southerly flow into westerly flow south of the pre-Karl disturbance. By 8-9 September, anomalous westerly winds with the surge merge with and enhance the anomalous westerly winds associated with the CCKW passage, strengthening the low-level vorticity generation in the cyclonic shear of the merged CCKW-wind surge on the pre-Karl disturbance. However, despite this increase in vorticity and convection, the environment surrounding the pre-Karl disturbance remained unfavorable for several more days, with increased vertical wind shear and the convectively suppressed phase of a CCKW inhibiting further development before TC genesis occurred on 14 September. Despite this delayed development, the interplay of both mid-latitude and equatorial wave precursors likely contributed to the eventual genesis of TC Karl.

  11. The eightfold way model, the SU(3)-flavor model and the medium-strong interaction

    NASA Astrophysics Data System (ADS)

    Abbas, Syed Afsar

    2015-04-01

    Lack of any baryon number in the eightfold way model, and its intrinsic presence in the SU(3)-flavor model, has been a puzzle since the genesis of these models in 1961-1964. First we show that the conventional popular understanding of this puzzle is actually fundamentally wrong, and hence the problem being so old, begs urgently for resolution. In this paper we show that the issue is linked to the way that the adjoint representation is defined mathematically for a Lie algebra, and how it manifests itself as a physical representation. This forces us to distinguish between the global and the local charges and between the microscopic and the macroscopic models. As a bonus, a consistent understanding of the hitherto mysterious medium-strong interaction is achieved. We also gain a new perspective on how confinement arises in quantum chromodynamics.

  12. Preliminary Model of Porphyry Copper Deposits

    USGS Publications Warehouse

    Berger, Byron R.; Ayuso, Robert A.; Wynn, Jeffrey C.; Seal, Robert R.

    2008-01-01

    The U.S. Geological Survey (USGS) Mineral Resources Program develops mineral-deposit models for application in USGS mineral-resource assessments and other mineral resource-related activities within the USGS as well as for nongovernmental applications. Periodic updates of models are published in order to incorporate new concepts and findings on the occurrence, nature, and origin of specific mineral deposit types. This update is a preliminary model of porphyry copper deposits that begins an update process of porphyry copper models published in USGS Bulletin 1693 in 1986. This update includes a greater variety of deposit attributes than were included in the 1986 model as well as more information about each attribute. It also includes an expanded discussion of geophysical and remote sensing attributes and tools useful in resource evaluations, a summary of current theoretical concepts of porphyry copper deposit genesis, and a summary of the environmental attributes of unmined and mined deposits.

  13. G-bounce

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Easson, Damien A.; Sawicki, Ignacy; Vikman, Alexander, E-mail: easson@asu.edu, E-mail: ignacy.sawicki@uni-heidelberg.de, E-mail: alexander.vikman@cern.ch

    2011-11-01

    We present a wide class of models which realise a bounce in a spatially flat Friedmann universe in standard General Relativity. The key ingredient of the theories we consider is a noncanonical, minimally coupled scalar field belonging to the class of theories with Kinetic Gravity Braiding / Galileon-like self-couplings. In these models, the universe smoothly evolves from contraction to expansion, suffering neither from ghosts nor gradient instabilities around the turning point. The end-point of the evolution can be a standard radiation-domination era or an inflationary phase. We formulate necessary restrictions for Lagrangians needed to obtain a healthy bounce and illustratemore » our results with phase portraits for simple systems including the recently proposed Galilean Genesis scenario.« less

  14. North Siberian Permafrost reveals Holocene Arctic Winter Warming

    NASA Astrophysics Data System (ADS)

    Meyer, H.; Opel, T.; Laepple, T.; Alexander, D.; Hoffmann, K.; Werner, M.

    2014-12-01

    The Arctic climate has experienced a major warming over the past decades, which is unprecedented in the last 2000 yrs. There are, however, still major uncertainties about the temperature evolution during the Holocene. Most proxy reconstructions suggest a cooling in mid-and late Holocene (e.g. Wanner, 2008), whereas climate model simulations show only weak changes or even a moderate warming (e.g. Lohmann et al., 2013). In this study, we used ice wedges as promising permafrost climate archive studied by stable water isotope methods. Ice wedges may be identified by vertically oriented foliations, and they form by the repeated filling of winter thermal contraction cracks by snow melt water in spring. Therefore, the isotopic composition of wedge ice may be attributed to the climate conditions of the cold season (i.e. winter and spring). 42 samples of organic material enclosed in ice wedges have been directly dated by Radiocarbon methods. Here, we present the first terrestrial stable oxygen isotope record of Holocene winter temperatures in up to centennial-scale resolution based on permafrost ice wedges (Lena River Delta; Siberian Arctic). The Lena ice-wedge record shows that the recent isotopic temperatures are the highest of the past 7000 years. Despite similarities to Arctic temperature reconstructions of the last two millennia (Kaufman et al., 2009), it suggests a winter warming throughout the mid and late Holocene, opposite to most existing other proxy records (Wanner, 2008). This apparent contradiction can be explained by the seasonality of the ice-wedge genesis in combination with orbital and greenhouse gas forcing and is consistent with climate model simulations. We conclude that the present model-data mismatch might be an artefact of the summer bias of the existing proxy records and thus, our record helps to reconcile the understanding of the northern hemisphere Holocene temperature evolution. This is particular true for the Russian Arctic significantly underrepresented in Arctic-wide climate reconstructions. Kaufman, D. S. et al. Science 325, 1236-1239 (2009).Wanner, H. et al. Quat. Sci. Rev. 27, 1791-1828, (2008).Lohmann, G., Pfeiffer, M., Laepple, T., Leduc, G. & Kim, J. H. Clim. Past 9, 1807-1839, (2013).

  15. Impacts of SST anomalies in the Indian-Pacific basin on Northwest Pacific tropical cyclone activities during three super El Niño years

    NASA Astrophysics Data System (ADS)

    Zhan, Ruifen; Chen, Baode; Ding, Yihui

    2018-01-01

    This study investigated the impact of sea surface temperature (SST) in several important areas of the Indian-Pacific basin on tropical cyclone (TC) activity over the western North Pacific (WNP) during the developing years of three super El Niño events (1982, 1997, and 2015) based on observations and numerical simulations. During the super El Niño years, TC intensity was enhanced considerably, TC days increased, TC tracks mostly recurved along the coasts, and fewer TCs made landfall in China. These characteristics are similar to the strong ENSO-TC relationship but further above the climatological means than in strong El Niño years. It indicates that super El Niño events play a dominant role in the intensities and tracks of WNP TCs. However, there were clear differences in both numbers and positions of TC genesis among the different super El Niño years. These features could be attributed to the collective impact of SST anomalies (SSTAs) in the tropical central-eastern Pacific and East Indian Ocean (EIO) and the SST gradient (SSTG) between the southwestern Pacific and the western Pacific warm pool. During 2015, the EIO SSTA was extremely warm and the anomalous anticyclone in the western WNP was enhanced, resulting in fewer TCs than normal. In 1982, the EIO SSTA and spring SSTG showed negative anomalies, followed by an increased anomalous cyclone in the western WNP and equatorial vertical wind shear. This intensified the conversion of eddy kinetic energy from large-scale flows, favorable for the westward shift of TC genesis. Consequently, anomalous TC activities during the super El Niño years resulted mainly from combined SSTA impacts of different key areas over the Indian-Pacific basin.

  16. Physiognomy and timing of metasomatism in the southern Vourinos ultramafic suite, NW Greece: a chronicle of consecutive episodes of melt extraction and stagnation in the Neotethyan lithospheric mantle

    NASA Astrophysics Data System (ADS)

    Kapsiotis, Argyrios N.

    2016-04-01

    The southern Vourinos massif, located in the Hellenides orogenic belt, forms part of the mantle section of the homonymous Neotethyan ophiolite complex in the NW Greek mainland. The southern domain of the massif is comprised voluminous and strained peridotite outcrops with variable pyroxene and olivine modal abundances, ranging from harzburgite (sensu stricto) to olivine-rich harzburgite and fine- to coarse-grained dunite. These peridotites are intruded by a complex network of undeformed websterite to olivine-rich websterite dykes. The peridotite lithologies are characterized by high Cr# [=Cr/(Cr + Al)] values in Cr-spinel (0.54-0.80), elevated Mg# [=Mg/(Mg + Fe2+)] ratios in olivine (0.91-0.94), poor Al2O3 content in clinopyroxene (up to 1.85 wt%) and very low bulk-rock abundances of Al2O3 (up to 0.66 wt%), CaO (up to 0.84 wt%), V (up to 45 ppm), Sc (up to 11 ppm) and REE, which are suggestive of their strongly depleted nature. They also display a wide range of fO2 values that vary between the fayalite-magnetite-quartz (FMQ-2) and FMQ+1 buffers, signifying their genesis under anoxic to oxidizing conditions. Simple batch and fractional melting models cannot satisfactorily explain their ultradepleted composition, whereas whole-rock Ni/Yb versus Yb systematics can be simulated by up to 27 % closed-system, non-modal, dynamic melting of a primitive mantle source, implying their multifarious origin in a progressively changing, in space and time, geotectonic setting. Chromian spinel chemistry (Cr# vs. TiO2) provides evidence for two consecutive melt-peridotite interaction events pertaining to patent metasomatism. The first incident is related to the release of IAT melts from the deep parts of the southern Vourinos mantle segment, which reacted with harzburgites transforming them into olivine-rich harzburgites and replacive dunites, whereas mixing of different pulses of IAT melts with distinct SiO2 activities generated heterogeneously deformed, cumulitic dunites. The second event is linked to the genesis of MORB/IAT magmas that originally invaded harzburgites. The MORB/IAT melts, although intensely reactive at the stage of harzburgite impregnation, lost their ability to react and stagnated in the peridotite groundmass as they approached the conceivable boundary with olivine-rich harzburgite. Microtextural observations and compositional data support that the interstitial, unstrained clinopyroxene ± olivine aggregates recognized in the harzburgite varieties represent intergranular melt blebs that `chilled' in the mantle during an episode of rapid lithosphere exhumation. This is further corroborated by the absence of lavas with MORB/IAT geochemical affinities from the Vourinos extrusive sequence. Microstructural features of websterite veins suggest that their genesis cannot be ascribed to the melts that penetrated the peridotites that cross cut. In contrast, they retain marks of olivine assimilation from the wall rocks that was facilitated by interaction with olivine-undersaturated, arc-derived tholeiitic melts released at a late phase from the ultradepleted southern Vourinos mantle suite.

  17. Influence of Kuroshio Oceanic Eddies on North Pacific Weather Patterns

    NASA Astrophysics Data System (ADS)

    Ma, X.; Chang, P.; Saravanan, R.; Montuoro, R.; Hsieh, J. S.; Wu, D.; Lin, X.; Wu, L.; Jing, Z.

    2016-02-01

    High-resolution satellite observations reveal energetic meso-scale ocean eddy activity and positive correlation between meso-scale sea surface temperature (SST) and surface wind along oceanic frontal zones, such as the Kuroshio and Gulf Stream, suggesting a potential role of meso-scale oceanic eddies in forcing the atmosphere. Using a 27 km horizontal resolution Weather Research Forecasting (WRF) model forced with observed daily SST at 0.09° spatial resolution during boreal winter season, two ensembles of 10 WRF simulations, in one of which meso-scale SST variability induced by ocean eddies was suppressed, were conducted in the North Pacific to study the local and remote influence of meso-scale oceanic eddies in the Kuroshio Extention Region (KER) on the atmosphere. Suppression of meso-scale oceanic eddies results in a deep tropospheric response along and downstream of the KER, including a significant decrease (increase) in winter season mean rainfall along the KER (west coast of US), a reduction of storm genesis in the KER, and a southward shift of the jet stream and North Pacific storm track in the eastern North Pacific. The simulated local and remote rainfall response to meso-scale oceanic eddies in the KER is also supported by observational analysis. A mechanism invoking moist baroclinic instability is proposed as a plausible explanation for the linkage between meso-scale oceanic eddies in the KER and large-scale atmospheric response in the North Pacific. It is argued that meso-scale oceanic eddies can have a rectified effect on planetary boundary layer moisture, the stability of the lower atmosphere and latent heat release, which in turn affect cyclogenesis. The accumulated effect of the altered storm development downstream further contributes to the equivalent barotropic mean flow change in the eastern North Pacific basin.

  18. Combined effects of deforestation and doubled atmospheric CO{sub 2} concentrations on the climate of Amazonia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Costa, M.H.; Foley, J.A.

    2000-01-01

    It is generally expected that the Amazon basin will experience at least two major environmental changes during the next few decades and centuries: (1) increasing areas of forest will be converted to pasture and cropland, and (2) concentrations of atmospheric CO{sub 2} will continue to rise. In this study, the authors use the National Center for Atmospheric Research GENESIS atmospheric general circulation model, coupled to the Integrated Biosphere Simulator, to determine the combined effects of large-scale deforestation and increased CO{sub 2} concentrations (including both physiological and radiative effects) on Amazonian climate. In these simulations, deforestation decreases basin-average precipitation by 0.73more » mm day{sup {minus}1} over the basin, as a consequence of the general reduction in vertical motion above the deforested area (although there are some small regions with increased vertical motion). The overall effect of doubled CO{sub 2} concentrations in Amazonia is an increase in basin-average precipitation of 0.28 mm day{sup {minus}1}. The combined effect of deforestation and doubled CO{sub 2}, including the interactions among the processes, is a decrease in the basin-average precipitation of 0.42 mm day{sup {minus}1}. While the effects of deforestation and increasing CO{sub 2} concentrations on precipitation tend to counteract one another, both processes work to warm the Amazon basin. The effect of deforestation and increasing CO{sub 2} concentrations both tent to increase surface temperature, mainly because of decreases in evapotranspiration and the radiative effect of CO{sub 2}. The combined effect of deforestation and doubled CO{sub 2}, including the interactions among the processes, increases the basin-average temperature by roughly 3.5 C.« less

  19. A socio-historical approach to policy analysis: the case of the Brazilian Workers' Food Policy.

    PubMed

    Costa-Souza, Jamacy; Vieira-da-Silva, Ligia Maria; Pinell, Patrice

    2018-02-05

    Policy analyses based on traditional or structuralist definitions of the state are important, but they have some limitations for explaining processes related to policymaking, implementation, and results. Bourdieusian sociology links the analysis to objective and subjective dimensions of social practices and can help elucidate these phenomena. This article provides such empirical evidence by analyzing the social genesis of a Brazilian policy that currently serves 18 million workers and was established by the state in 1976 through the Fiscal Incentives Program for Workers' Nutrition (PIFAT/PAT). The study linked the analysis of the trajectory of social agents involved in the policy's formulation to the historical conditions that allowed the policy to exist in the first place. Although the literature treats the policy as a workers' food program (PAT), the current study showed that it actually represented a new model for paying financial subsidies to companies that provided food to their employees, meanwhile upgrading the commercial market for collective meals. The study further showed that the program emerged as an administrative policy, but linked to economic agents. The program became a specific social space in which issues related to workers' nutrition became secondary, but useful for disguising what had been an explicit side of its genesis, namely its essentially fiscal nature.

  20. A key role for green rust in the Precambrian oceans and the genesis of iron formations

    NASA Astrophysics Data System (ADS)

    Halevy, I.; Alesker, M.; Schuster, E. M.; Popovitz-Biro, R.; Feldman, Y.

    2017-01-01

    Iron formations deposited in marine settings during the Precambrian represent large sinks of iron and silica, and have been used to reconstruct environmental conditions at the time of their formation. However, the observed mineralogy in iron formations, which consists of iron oxides, silicates, carbonates and sulfides, is generally thought to have arisen from diagenesis of one or more mineral precursors. Ferric iron hydroxides and ferrous carbonates and silicates have been identified as prime candidates. Here we investigate the potential role of green rust, a ferrous-ferric hydroxy salt, in the genesis of iron formations. Our laboratory experiments show that green rust readily forms in early seawater-analogue solutions, as predicted by thermodynamic calculations, and that it ages into minerals observed in iron formations. Dynamic models of the iron cycle further indicate that green rust would have precipitated near the iron redoxcline, and it is expected that when the green rust sank it transformed into stable phases within the water column and sediments. We suggest, therefore, that the precipitation and transformation of green rust was a key process in the iron cycle, and that the interaction of green rust with various elements should be included in any consideration of Precambrian biogeochemical cycles.

  1. Optimization for Single-Spike X-Ray FELs at LCLS with a Low Charge Beam

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, L.; Ding, Y.; Huang, Z.

    2011-12-14

    The Linac Coherent Light Source is an x-ray free-electron laser at the SLAC National Accelerator Laboratory, which is operating at x-ray wavelengths of 20-1.2 Angstrom with peak brightness nearly ten orders of magnitude beyond conventional synchrotron radiation sources. At the low charge operation mode (20 pC), the x-ray pulse length can be <10 fs. In this paper we report our numerical optimization and simulations to produce even shorter x-ray pulses by optimizing the machine and undulator setup at 20 pC charge. In the soft x-ray regime, with combination of slotted-foil or undulator taper, a single spike x-ray pulse is achievablemore » with peak FEL power of a few 10s GW. Linac Coherent Light Source (LCLS), the world's first hard x-ray Free electron laser (FEL), has started operation since 2009. With nominal operation charge of 250 pC, the generated x-ray pulse length is from 70 fs to a few hundred fs. This marks the beginning of a new era of ultrashort x-ray sciences. In addition, a low charge (20pC) operation mode has also been established. Since the collective effects are reduced at the low charge mode, we can increase the compression factor and still achieve a few kA peak current. The expected electron beam and x-ray pulses are less than 10 fs. There are growing interests in even shorter x-ray pulses, such as fs to sub-fs regime. One of the simple solutions is going to even lower charge. As discussed, single-spike x-ray pulses can be generated using 1 pC charge. However, this charge level is out of the present LCLS diagnostic range. 20 pC is a reasonable operation charge at LCLS, based on the present diagnostic system. At 20 pC in the soft x-ray wavelength regime, we have experimentally demonstrated that FEL can work at undercompression or over-compression mode, such as 1 degree off the full-compression; at full-compression, however, there is almost no lasing. In hard x-ray wavelength regime, we observed that there are reasonable photons generated even at full-compression mode, although the photon number is less than that from under-compression or over-compression mode. Since we cannot measure the x-ray pulse length at this time scale, the machine is typically optimized for generating maximum photons, not minimum pulse length. In this paper, we study the methods of producing femtosecond (or single-spike) x-ray pulses at LCLS with 20 pC charge, based on start-to-end simulations. Figure 1 shows a layout of LCLS. The compression in the second bunch compressor (BC2) determines the final e-beam bunch length. However, the laser heater, dog-leg after the main linac (DL2) and collective effects also affect the final bunch length. To adjust BC2 compression, we can either change the L2 phase or BC2 R{sub 56}. In this paper we only tune L2 phase while keep BC2 R{sub 56} fixed. For the start-to-end simulations, we used IMPACT-T and ELEGANT tracking from the photocathode to the entrance of the undulator, after that the FEL radiation was simulated with GENESIS. IMPACT-T tracks about 10{sup 6} particles in the injector part until 135 MeV, including 3D space charge force. The output particles from IMPACT-T are smoothed and increased to 12 x 10{sup 6} to reduce high-frequency numerical noise for subsequent ELEGANT simulations, which include linear and nonlinear transport effects, a 1D transient model of CSR, and longitudinal space charge effects, as well as geometric and resistive wake fields in the accelerator. In GENESIS part, the longitudinal wake field from undulator chamber and longitudinal space field are also included.« less

  2. Understanding the geographic distribution of tropical cyclone formation for applications in climate models

    NASA Astrophysics Data System (ADS)

    Tory, Kevin J.; Ye, H.; Dare, R. A.

    2018-04-01

    Projections of Tropical cyclone (TC) formation under future climate scenarios are dependent on climate model simulations. However, many models produce unrealistic geographical distributions of TC formation, especially in the north and south Atlantic and eastern south Pacific TC basins. In order to improve confidence in projections it is important to understand the reasons behind these model errors. However, considerable effort is required to analyse the many models used in projection studies. To address this problem, a novel diagnostic is developed that provides compelling insight into why TCs form where they do, using a few summary diagrams. The diagnostic is developed after identifying a relationship between seasonal climatologies of atmospheric variables in 34 years of ECMWF reanalysis data, and TC detection distributions in the same data. Geographic boundaries of TC formation are constructed from four threshold quantities. TCs form where Emanuel's Maximum Potential Intensity, V_{{PI}}, exceeds 40 {ms}^{{ - 1}}, 700 hPa relative humidity, RH_{{700}}, exceeds 40%, and the magnitude of the difference in vector winds between 850 and 200 hPa, V_{{sh}}, is less than 20 {ms}^{{ - 1}}. The equatorial boundary is best defined by a composite quantity containing the ratio of absolute vorticity (η ) to the meridional gradient of absolute vorticity (β ^{*}), rather than η alone. {β ^*} is also identified as a potentially important ingredient for TC genesis indices. A comparison of detected Tropical Depression (TD) and Tropical Storm (TS) climatologies revealed TDs more readily intensify further to TS where {V_{PI}} is elevated and {V_{sh}} is relatively weak. The distributions of each threshold quantity identify the factors that favour and suppress TC formation throughout the tropics in the real world. This information can be used to understand why TC formation is poorly represented in some climate models, and shows potential for understanding anomalous TC formation behaviour in the real world.

  3. The footprints of Saharan air layer and lightning on the formation of tropical depressions over the eastern Atlantic Ocean

    NASA Astrophysics Data System (ADS)

    Centeno Delgado, Diana C.; Chiao, Sen

    2015-02-01

    The roles of the Saharan Air Layer (SAL) and lightning during genesis of Tropical Depression (TD) 8 (2006) and TD 12 (2010) were investigated in relation to the interaction of the dust outbreaks with each system and their surrounding environment. This study applied data collected from the 2006 NASA African Monsoon Multidisciplinary Analysis and 2010 Genesis and Rapid Intensification Processes projects. Satellite observations from METEOSAT and Moderate Resolution Imaging Spectroradiometer (MODIS)—Aerosol Optical Depth (AOD) were also employed for the study of the dust content. Lightning activity data from the Met Office Arrival Time Difference (ATD) system were used as another parameter to correlate moist convective overturning and a sign of cyclone formation. The AOD and lightning analysis for TD 8 demonstrated the time-lag connection through their positive contribution to TC-genesis. TD 12 developed without strong dust outbreak, but with lower wind shear (2 m s-1) and an organized Mesoscale Convective System (MCS). Overall, the results from the combination of various data analyses in this study support the fact that both systems developed under either strong or weak dust conditions. From these two cases, the location (i.e., the target area) of strong versus weak dust outbreaks, in association with lightning, were essential interactions that impacted TC-genesis. While our dust footprints hypothesis applied under strong dust conditions (i.e., TD 8), other factors (e.g., vertical wind shear, pre-existing vortex and trough location, thermodynamics) need to be evaluated as well. The results from this study suggest that the SAL is not a determining factor that affects the formation of tropical cyclones (i.e., TD 8 and TD 12).

  4. Clean Assembly of Genesis Collector Canister for Flight: Lessons for Planetary Sample Return

    NASA Technical Reports Server (NTRS)

    Allton, J. H.; Stansbery, E. K.; Allen, C. C.; Warren, J. L.; Schwartz, C. M.

    2007-01-01

    Measurement of solar composition in the Genesis collectors requires not only high sensitivity but very low blanks; thus, very strict collector contamination minimization was required beginning with mission planning and continuing through hardware design, fabrication, assembly and testing. Genesis started with clean collectors and kept them clean inside of a canister. The mounting hardware and container for the clean collectors were designed to be cleanable, with access to all surfaces for cleaning. Major structural components were made of aluminum and cleaned with megasonically energized ultrapure water (UPW). The UPW purity was >18 M resistivity. Although aluminum is relatively difficult to clean, the Genesis protocol achieved level 25 and level 50 cleanliness on large structural parts; however, the experience suggests that surface treatments may be helpful on future missions. All cleaning was performed in an ISO Class 4 (Class 10) cleanroom immediately adjacent to an ISO Class 4 assembly room; thus, no plastic packaging was required for transport. Persons assembling the canister were totally enclosed in cleanroom suits with face shield and HEPA filter exhaust from suit. Interior canister materials, including fasteners, were installed, untouched by gloves, using tweezers and other stainless steel tools. Sealants/lubricants were not exposed inside the canister, but vented to the exterior and applied in extremely small amounts using special tools. The canister was closed in ISO Class 4, not to be opened until on station at Earth-Sun L1. Throughout the cleaning and assembly, coupons of reference materials that were cleaned at the same time as the flight hardware were archived for future reference and blanks. Likewise reference collectors were archived. Post-mission analysis of collectors has made use of these archived reference materials.

  5. Elemental Redistribution at the Onset of Soil Genesis from Basalt as Measured in a Soil Lysimeter System

    NASA Astrophysics Data System (ADS)

    Wang, Y.; Umanzor, M.; Alves Meira Neto, A.; Sengupta, A.; Amistadi, M. K.; Root, R.; Troch, P.; Chorover, J.

    2017-12-01

    Elemental translocation, resulting in enrichment or depletion relative to parent rock, is a consequence of mineral dissolution and precipitation reactions of soil genesis. Accurate measurement of translocation in natural systems is complicated by factors such as parent material heterogeneity and dust deposition. In the present work, a fully controlled and monitored 10° sloping soil lysimeter with known homogeneous initial conditions, was utilized to investigate initial stages of soil genesis from 1 m3 of crushed basalt. Throughout the two-year experiment, periodic irrigation coupled with sensor measurements enabled monitoring of changes in internal moisture states. A total 15-meter water influx resulted in distinct efflux patterns, wetting and drying cycles, as well as high volume water storage. Biological changes, such as algal and grass emergence, were visible on the soil surface, and microbial colonization throughout the profile was measured in a companion study, suggesting that biogeochemical hotspots may have formed. Forensic excavation and sampling of 324 voxels captured the final state heterogeneity of the lysimeter with respect to length and depth. Total elemental concentrations and a five-step sequential extraction (SE) scheme quantified elemental redistributions into operationally-defined pools including exchangeable, poorly-crystalline (hydr)oxides, and crystalline (hydr)oxides. Data were correlated to water flux and storage that was determined from sensor and tracer data over the two years of rock-water interaction; then used to map 2D cross-sections and identify geochemical hotspots. Total and SE Fe concentrations were used to establish a governing mass balance equation, and sub mass balance equations with unique partitioning coefficients of Fe were developed for each SE pool, respectively. The results help to explain elemental (e.g., Fe) lability and redistribution due to physical and geochemical weathering during the initial stages of soil genesis.

  6. 3D Volume and Morphology of Perennial Cave Ice and Related Geomorphological Models at Scăriloara Ice Cave, Romania, from Structure from Motion, Ground Penetrating Radar and Total Station Surveys

    NASA Astrophysics Data System (ADS)

    Hubbard, J.; Onac, B. P.; Kruse, S.; Forray, F. L.

    2017-12-01

    Research at Scăriloara Ice Cave has proceeded for over 150 years, primarily driven by the presence and paleoclimatic importance of the large perennial ice block and various ice speleothems located within its galleries. Previous observations of the ice block led to rudimentary volume estimates of 70,000 to 120,000 cubic meters (m3), prospectively placing it as one of the world's largest cave ice deposits. The cave morphology and the surface of the ice block are now recreated in a total station survey-validated 3D model, produced using Structure from Motion (SfM) software. With the total station survey and the novel use of ArcGIS tools, the SfM validation process is drastically simplified to produce a scaled, georeferenced, and photo-texturized 3D model of the cave environment with a root-mean-square error (RMSE) of 0.24 m. Furthermore, ground penetrating radar data was collected and spatially oriented with the total station survey to recreate the ice block basal surface and was combined with the SfM model to create a model of the ice block itself. The resulting ice block model has a volume of over 118,000 m3 with an uncertainty of 9.5%, with additional volumes left un-surveyed. The varying elevation of the ice block basal surface model reflect specific features of the cave roof, such as areas of enlargement, shafts, and potential joints, which offer further validation and inform theories on cave and ice genesis. Specifically, a large depression area was identified as a potential area of initial ice growth. Finally, an ice thickness map was produced that will aid in the designing of future ice coring projects. This methodology presents a powerful means to observe and accurately characterize and measure cave and cave ice morphologies with ease and affordability. Results further establish the significance of Scăriloara's ice block to paleoclimate research, provide insights into cave and ice block genesis, and aid future study design.

  7. Imaging the supermassive black hole shadow and jet base of M87 with the event horizon telescope

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lu, Ru-Sen; Fish, Vincent L.; Doeleman, Sheperd S.

    2014-06-20

    The Event Horizon Telescope (EHT) is a project to assemble a Very Long Baseline Interferometry (VLBI) network of millimeter wavelength dishes that can resolve strong field general relativistic signatures near a supermassive black hole. As planned, the EHT will include enough dishes to enable imaging of the predicted black hole 'shadow', a feature caused by severe light bending at the black hole boundary. The center of M87, a giant elliptical galaxy, presents one of the most interesting EHT targets as it exhibits a relativistic jet, offering the additional possibility of studying jet genesis on Schwarzschild radius scales. Fully relativistic modelsmore » of the M87 jet that fit all existing observational constraints now allow horizon-scale images to be generated. We perform realistic VLBI simulations of M87 model images to examine the detectability of the black shadow with the EHT, focusing on a sequence of model images with a changing jet mass load radius. When the jet is launched close to the black hole, the shadow is clearly visible both at 230 and 345 GHz. The EHT array with a resolution of 20-30 μas resolution (∼2-4 Schwarzschild radii) is able to image this feature independent of any theoretical models and we show that imaging methods used to process data from optical interferometers are applicable and effective for EHT data sets. We demonstrate that the EHT is also capable of tracing real-time structural changes on a few Schwarzschild radii scales, such as those implicated by very high-energy flaring activity of M87. While inclusion of ALMA in the EHT is critical for shadow imaging, the array is generally robust against loss of a station.« less

  8. Gas hydrate saturation and distribution in the Kumano Forearc Basin of the Nankai Trough

    NASA Astrophysics Data System (ADS)

    Jia, Jihui; Tsuji, Takeshi; Matsuoka, Toshifumi

    2017-02-01

    The Kumano Forearc Basin is located to the south-east of the Kii Peninsula, Japan, overlying the accretionary prism in the Nankai Trough. The presence of gas hydrate in submarine sediments of the forearc basin has resulted in the widespread occurrence of bottom simulating reflectors (BSRs) on seismic profiles, and has caused distinct anomalies in logging data in the region. We estimated the in situ gas hydrate saturation from logging data by using three methods: effective rock physics models, Archie's equation, and empirical relationships between acoustic impedance (AI) and water-filled porosity. The results derived from rock physics models demonstrate that gas hydrates are attached to the grain surfaces of the rock matrix and are not floating in pore space. By applying the empirical relationships to the AI distribution derived from model-based AI inversion of the three-dimensional (3D) seismic data, we mapped the spatial distribution of hydrate saturation within the Kumano Basin and characterised locally concentrated gas hydrates. Based on the results, we propose two different mechanisms of free gas supply to explain the process of gas hydrate formation in the basin: (1) migration along inclined strata that dip landwards, and (2) migration through the faults or cracks generated by intensive tectonic movements of the accretionary prism. The dipping strata with relatively low AI in the forearc basin could indicate the presence of hydrate formation due to gas migration along the dipping strata. However, high hydrate concentration is observed at fault zones with high pore pressures, thus the second mechanism likely plays an important role in the genesis of gas hydrates in the Kumano Basin. Therefore, the tectonic activities in the accretionary wedge significantly influence the hydrate saturation and distribution in the Kumano Forearc Basin.

  9. Example of trondhjemite genesis by means of alkali metasomatism: Rockford Granite, Alabama Appalachians

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Drummond, M.S.; Wesolowski, D.; Ragland, P.C.

    1985-01-01

    An alternative model for trondhjemite genesis is proposed where granite is transformed to trondhjemite via infiltration by a Na-rich metamorphic fluid. The Rockford Granite serves as the case example for this process and is characterized as a synmetamorphic, peraluminous trondhjemite-granite suite. The major process operative in the conversion of granite to trondhjemite involves cation exchange of Na for K in the feldspar and mica phases through a volatile fluid medium. Whole-rock delta/sup 18/O values for the trondhjemites are negatively correlated with the atomic prop. K/Na ratio indicating a partial reequilibration of the altered granitoids with a Na- and /sup 18/O-richmore » metamorphically derived fluid. Biotite decomposition to an Al-epidote-paragonitic muscovite-quartz assemblage is also associated with the Na-metasomatism, as are apatite replacement by Al-epidote and secondary zircon crystallization. The replacement of magmatic phases by metasomatic phases exemplifies the chemical changes produced during infiltration metasomatism where the trondhjemites are depleted in all REE's. The timing of the infiltration metasomatism is thought to have occurred during regional metamorphism, producing a discrete fluid phase in the surrounding amphibolite-grade metasediments. Foliation planes in the granitoid apparently served as conduts for fluid flow with reaction enhanced permeability accompanying the 8% molar volume reduction during Na for K exchange in the feldspars. A model is proposed where metamorphic fluids migrated updip and along strike from their source and were buffered by the presence or absence of two feldspars in the metasediments.« less

  10. Mechanical Modulation of Nascent Stem Cell Lineage Commitment in Tissue Engineering Scaffolds

    PubMed Central

    Song, Min Jae; Dean, David; Tate, Melissa L. Knothe

    2013-01-01

    Taking inspiration from tissue morphogenesis in utero, this study tests the concept of using tissue engineering scaffolds as delivery devices to modulate emergent structure-function relationships at early stages of tissue genesis. We report on the use of a combined computational fluid dynamics (CFD) modeling, advanced manufacturing methods, and experimental fluid mechanics (micro-piv and strain mapping) for the prospective design of tissue engineering scaffold geometries that deliver spatially resolved mechanical cues to cells seeded within. When subjected to a constant magnitude global flow regime, the local scaffold geometry dictates the magnitudes of mechanical stresses and strains experienced by a given cell, and in a spatially resolved fashion, similar to patterning during morphogenesis. In addition, early markers of mesenchymal stem cell lineage commitment relate significantly to the local mechanical environment of the cell. Finally, by plotting the range of stress-strain states for all data corresponding to nascent cell lineage commitment (95% CI), we begin to “map the mechanome”, defining stress-strain states most conducive to targeted cell fates. In sum, we provide a library of reference mechanical cues that can be delivered to cells seeded on tissue engineering scaffolds to guide target tissue phenotypes in a temporally and spatially resolved manner. Knowledge of these effects allows for prospective scaffold design optimization using virtual models prior to prototyping and clinical implementation. Finally, this approach enables the development of next generation scaffolds cum delivery devices for genesis of complex tissues with heterogenous properties, e.g., organs, joints or interface tissues such as growth plates. PMID:23660249

  11. Mechanical modulation of nascent stem cell lineage commitment in tissue engineering scaffolds.

    PubMed

    Song, Min Jae; Dean, David; Knothe Tate, Melissa L

    2013-07-01

    Taking inspiration from tissue morphogenesis in utero, this study tests the concept of using tissue engineering scaffolds as delivery devices to modulate emergent structure-function relationships at early stages of tissue genesis. We report on the use of a combined computational fluid dynamics (CFD) modeling, advanced manufacturing methods, and experimental fluid mechanics (micro-piv and strain mapping) for the prospective design of tissue engineering scaffold geometries that deliver spatially resolved mechanical cues to stem cells seeded within. When subjected to a constant magnitude global flow regime, the local scaffold geometry dictates the magnitudes of mechanical stresses and strains experienced by a given cell, and in a spatially resolved fashion, similar to patterning during morphogenesis. In addition, early markers of mesenchymal stem cell lineage commitment relate significantly to the local mechanical environment of the cell. Finally, by plotting the range of stress-strain states for all data corresponding to nascent cell lineage commitment (95% CI), we begin to "map the mechanome", defining stress-strain states most conducive to targeted cell fates. In sum, we provide a library of reference mechanical cues that can be delivered to cells seeded on tissue engineering scaffolds to guide target tissue phenotypes in a temporally and spatially resolved manner. Knowledge of these effects allows for prospective scaffold design optimization using virtual models prior to prototyping and clinical implementation. Finally, this approach enables the development of next generation scaffolds cum delivery devices for genesis of complex tissues with heterogenous properties, e.g., organs, joints or interface tissues such as growth plates. Copyright © 2013 Elsevier Ltd. All rights reserved.

  12. Modeling the sustainable development of innovation in transport construction based on the communication approach

    NASA Astrophysics Data System (ADS)

    Revunova, Svetlana; Vlasenko, Vyacheslav; Bukreev, Anatoly

    2017-10-01

    The article proposes the models of innovative activity development, which is driven by the formation of “points of innovation-driven growth”. The models are based on the analysis of the current state and dynamics of innovative development of construction enterprises in the transport sector and take into account a number of essential organizational and economic changes in management. The authors substantiate implementing such development models as an organizational innovation that has a communication genesis. The use of the communication approach to the formation of “points of innovation-driven growth” allowed the authors to apply the mathematical tools of the graph theory in order to activate the innovative activity of the transport industry in the region. As a result, the authors have proposed models that allow constructing an optimal mechanism for the formation of “points of innovation-driven growth”.

  13. Tropical Cyclones, Hurricanes, and Climate: NASA's Global Cloud-Scale Simulations and New Observations that Characterize the Lifecycle of Hurricanes

    NASA Technical Reports Server (NTRS)

    Putman, William M.

    2010-01-01

    One of the primary interests of Global Change research is the impact of climate changes and climate variability on extreme weather events, such as intense tropical storms and hurricanes. Atmospheric climate models run at resolutions of global weather models have been used to study the impact of climate variability, as seen in sea surface temperatures, on the frequency and intensity of tropical cyclones. NASA's Goddard Earth Observing System Model, version 5 (GEOS-5) in ensembles run at 50 km resolution has been able to reproduce the interannual variations of tropical cyclone frequency seen in nature. This, and other global models, have found it much more difficult to reproduce the interannual changes in intensity, a result that reflects the inability of the models to simulate the intensities of the most extreme storms. Better representation of the structures of cyclones requires much higher resolution models. Such improved representation is also fundamental to making best use of satellite observations. In collaboration with NOAA's Geophysical Fluid Dynamics Laboratory, GEOS-5 now has the capability of running at much higher resolution to better represent cloud-scale resolutions. Global simulations at cloud-permitting resolutions (10- to 3.5-km) allows for the development of realistic tropical cyclones from tropical storm 119 km/hr winds) to category 5 (>249km1hr winds) intensities. GEOS-5 has produced realistic rain-band and eye-wall structures in tropical cyclones that can be directly analyzed against satellite observations. For the first time a global climate model is capable of representing realistic intensity and track variability on a seasonal scale across basins. GEOS-5 is also used in assimilation mode to test the impact of NASA's observations on tropical cyclone forecasts. One such test, for tropical cyclone Nargis in the Indian Ocean in May 2008, showed that observations from Atmospheric Infrared Sounder (AIRS) and the Advanced Microwave Sounding Unit (AMSU-A) on Aqua substantially reduced forecast track errors. Tropical cyclones in the northern Indian Ocean pose serious challenges to operational weather forecasting systems, partly due to their shorter lifespan and more erratic track, compared to those in the Atlantic and the Pacific. SA is also bringing several state of the art instruments in recent field campaigns to peer under the clouds and study the inner workings of the tropical storms. With the Genesis and Rapid Intensification Processes (GRIP) experiment, a NASA Earth science field experiment in 2010 that includes the Global Hawk Unmanned Airborne System (UAS) configured with a suite of in situ and remote sensing instruments that are observing and characterizing the lifecycle of hurricanes, we expect significant improvement in our understanding of the track and intensification processes with the assimilation of the satellite and field campaign observations of meteorological parameters in the numerical prediction models.

  14. JPL Genesis and Rapid Intensification Processes (GRIP) Portal

    NASA Technical Reports Server (NTRS)

    Knosp, Brian W.; Li, P. Peggy; Vu, Quoc A.; Turk, Francis J.; Shen, Tsae-Pyng J.; Hristova-Veleva, Svetla M.; Licata, Stephen J.; Poulsen, William L.

    2012-01-01

    Satellite observations can play a very important role in airborne field campaigns, since they provide a comprehensive description of the environment that is essential for the experiment design, flight planning, and post-experiment scientific data analysis. In the past, it has been difficult to fully utilize data from multiple NASA satellites due to the large data volume, the complexity of accessing NASA s data in near-real-time (NRT), as well as the lack of software tools to interact with multi-sensor information. The JPL GRIP Portal is a Web portal that serves a comprehensive set of NRT observation data sets from NASA and NOAA satellites describing the atmospheric and oceanic environments related to the genesis and intensification of the tropical storms in the North Atlantic Ocean. Together with the model forecast data from four major global atmospheric models, this portal provides a useful tool for the scientists and forecasters in planning and monitoring the NASA GRIP field campaign during the 2010 Atlantic Ocean hurricane season. This portal uses the Google Earth plug-in to visualize various types of data sets, such as 2D maps, wind vectors, streamlines, 3D data sets presented at series of vertical cross-sections or pointwise vertical profiles, and hurricane best tracks and forecast tracks. Additionally, it allows users to overlap multiple data sets, change the opacity of each image layer, generate animations on the fly with selected data sets, and compare the observation data with the model forecast using two independent calendars. The portal also provides the capability to identify the geographic location of any point of interest. In addition to supporting the airborne mission planning, the NRT data and portal will serve as a very rich source of information during the post-field campaign analysis stage of the airborne experiment. By including a diverse set of satellite observations and model forecasts, it provides a good spatial and temporal context for the high-resolution, but limited in space and time, airborne observations.

  15. Seasonal prediction of typhoon genesis frequency and track patterns in the North West Pacific area

    NASA Astrophysics Data System (ADS)

    Hyoun, Yoosun; Kang, Kiryong; Shin, Do-Shick

    2014-05-01

    This study is to investigate the performance of the typhoon seasonal predictability using a dynamical model. The check items are the monthly statistics for total number of typhoon genesis in Western North Pacific (WNP) area and possible threat to Korean peninsula among them, and the probability of each categorized track pattern. As the dynamical model the Florida State University/Center for Ocean-Atmospheric Prediction Studies (FSU/COAPS) was used, and it uses five ensemble members including control run are generated using time-lagged methods and the resolution of T126L27 (a Gaussian grid spacing of 0.94º). The model initial conditions are obtained from the National Center for Enviromental Prediction Global Forecast System (NCEP GFS) and the SST from Climate Forecast System with bias correction was used for ocean surface boundary condition. The summer (Jun-Jul-Aug) season prediction is made one month prior to target season. The detection of tropical cyclone used in this system is based on six criteria. First, the isolated vortex type minimum sea level pressure should be below 1008hPa. Second, the maximum wind speed is larger than 17m s-1. Third, the magnitude of the maximum relative vorticity at 850hPa exceeds 3.5x10-5s-1. Fourth, the average temperature difference from the area mean of surrounding region at 300hPa, 500hPa, 700hPa exceeds 2.5K. Fifth, the maximum wind speed at 850hPa is larger than that at 300hPa. Sixth, this identified vortex should last more than two days. These criteria were chosen after close examination from model-observation comparison. In this study, we will focus on performance of the system typhoon frequency and track pattern in the WNP area during 2004-2013.

  16. Optimization of the LCLS X-Ray FEL Output Performance in the Presence of Strong Undulator Wakefields

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Reiche, S.; /UCLA; Bane, K.L.F.

    The Linac Coherent Light Source (LCLS) Free-Electron Laser will operate in the wavelength range of 1.5 to 15 Angstroms. Energy loss due to wakefields within the long undulator can degrade the FEL process by detuning the resonant FEL frequency. The wakefields arise from the vacuum chamber wall resistivity, its surface roughness, and abrupt changes in its aperture. For LCLS parameters, the resistive component is the most critical and depends upon the chamber material (e.g. Cu) and its radius. To study the expected performance in the presence of these wakefields, we make a series of start-to-end simulations with tracking codes PARMELAmore » and ELEGANT and time-dependent FEL simulation codes Genesis 1.3 and Ginger. We discuss the impact of the wakefield on output energy, spectral bandwidth, and temporal envelope of the output FEL pulse, as well as the benefits of a partial compensation obtained with a slight z dependent taper in the undulator field. We compare these results to those obtained by decreasing the bunch charge or increasing the vacuum chamber radius. We also compare our results to those predicted in concurrent analytical work.« less

  17. Accounting for mudflow genesis in preliminary assessment of the maximum volume of solid mudflow sediments in the North Caucasus

    NASA Astrophysics Data System (ADS)

    Zalikhanov, M. Ch.; Kondratieva, N. V.; Adzhiev, A. Kh.; Razumov, V. V.

    2016-09-01

    The area of investigation was subject to multifactor analysis of the relationship between the maximum amount of mudflow solid sediments ( W) and parameters such as the mudflow basin area ( S), average channel slope (α), and mudflow channel length ( L). They were used to obtain analytical expressions in order to approximate the W( S, L, α) relation based on the mudflow genesis and source height. Statistical data on mudflow manifestations in different basins in the North Caucasus covering more than fifty years were used to obtain the analytical expressions in order to assess the maximum volume of mudflow solid sediments.

  18. Liver physiological polyploidization: MicroRNA-122 a key regulator.

    PubMed

    Celton-Morizur, Séverine; Desdouets, Chantal

    2017-03-01

    Polyploidy is defined as an increase in genome DNA content and is observed in all mammalian species. Polyploidy is a common characteristic of hepatocytes. Polyploidization occurs mainly during liver development, but also in adults with increasing age or due to cellular stress. During liver development, hepatocytes polyploidization occurs through cytokinesis failure leading to the genesis of binucleate hepatocytes. Recently, Hsu et al. demonstrated that miR-122 is a key regulator of hepatic binucleation. In fact, during liver development, miR-122 directly antagonizes procytokinesis targets and thus induces cytokinesis failure leading to the genesis of binucleate hepatocytes. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  19. Genesis of Atlantic Lows Experiment NASA Electra Boundary Layer Flights Data Report

    NASA Technical Reports Server (NTRS)

    Palm, Stephen P.; Melfi, S. H.; Boers, Reinout

    1988-01-01

    The objective of this research was to obtain high resolution measurements of the height of the Marine Atmospheric Boundary Layer (MABL) during cold air outbreaks using an Airborne Lidar System. The research was coordinated with other investigators participating in the Genesis of Atlantic Lows Experiment (GALE). An objective computerized scheme was developed to obtain the Boundary Layer Height from the Lidar Data. The algorithm was used on each of the four flight days producing a high resolution data set of the MABL height over the GALE experiment area. Plots of the retrieved MABL height as well as tabular data summaries are presented.

  20. Genesis Noble Gas Measurements

    NASA Technical Reports Server (NTRS)

    Hohenberg, Charles M.

    2005-01-01

    The original thrust of our Genesis funding was to extend and refine the noble gas analytical capabilities of this laboratory to improve the precision and accuracy of noble gas measurements in order to optimize the scientific return from the Genesis Mission. This process involved both instrumental improvement (supplemented by a SRLIDAP instrument grant) and refinement of technique. The Genesis landing mishap shifted our emphasis to the irregular aluminum heat shield material from the flat collector wafers. This has required redesign of our laser extraction cells to accommodate the longer focal lengths required for laser extraction from non-flat surfaces. Extraction of noble gases from solid aluminum surfaces, rather than thin coatings on transparent substrates has required refinement of controlled-depth laser ablation techniques. Both of these bring new problems, both with potentially higher blanks form larger laser cells and the larger quantities of evaporated aluminum which can coat the sapphire entrance ports. This is mainly a problem for the heavy noble gases where larger extraction areas are required, necessitating the new aluminum vapor containment techniques described below. With the Genesis Mission came three new multiple multiplier noble gas mass spectrometers to this laboratory, one built solely by us (Supergnome-M), one built in collaboration with Nu-Instruments (Noblesse), and one built in collaboration with GVI (Helix). All of these have multiple multiplier detection sections with the Nu-Instruments using a pair of electrostatic quad lenses for isotope spacing and the other two using mechanically adjustable positions for the electron multipliers. The Supergnome-M and Noblesse are installed and running. The GVI instrument was delivered a year late (in March 2005) and is yet to be installed by GVI. As with all new instruments there were some initial development issues, some of which are still outstanding. The most serious of these are performance issues with the miniature channel electron multipliers. The delayed installation of Helix by the GVI is partly due to failure of the initial batch of Burle channel multipliers to perform as expected. A number of the channel multipliers designed for Noblesse by Burle have also failed upon baking. Burle has now refined the design of these and we have installed two of the new multipliers and are assessing their performance. The remaining multipliers Will be upgraded to the new design from Burle once we confirm that the problem has been fixed.

  1. The Genesis Mission: Contamination Control and Curation

    NASA Technical Reports Server (NTRS)

    Stansbery, E. K.

    2002-01-01

    The Genesis mission, launched in August 2001, is collecting samples of the solar wind and will return to Earth in 2004. Genesis can be viewed as the most fundamental of NASA's sample return missions because it is expected to provide insight into the initial elemental and isotopic composition of the solar nebula from which all other planetary objects formed. The data from this mission will have a large impact on understanding the origins and diversity of planetary materials. The collectors consist of clean, pure materials into which the solar wind will imbed. Science and engineering issues such as bulk purity, cleanliness, retention of solar wind, and ability to withstand launch and entry drove material choices. Most of the collector materials are installed on array frames that are deployed from a clean science canister. Two of the arrays are continuously exposed for collecting the bulk solar wind; the other three are only exposed during specific solar wind regimes as measured by ion and electron monitors. Other materials are housed as targets at the focal point of an electrostatic mirror, or "concentrator", designed to enhance the flux of specific solar wind species. Johnson Space Center (JSC) has two principal responsibilities for the Genesis mission: contamination control and curation. Precise and accurate measurements of the composition of the solar atoms require that the collector materials be extremely clean and well characterized before launch and during the mission. Early involvement of JSC curation personnel in concept development resulted in a mission designed to minimize contaminants from the spacecraft and operations. A major goal of the Genesis mission is to provide a reservoir of materials for the 21 51 century. When the collector materials are returned to Earth, they must be handled in a clean manner and their condition well documented. Information gained in preliminary examination of the arrays and detailed surveys of each collector will be used to guide sample allocations to the scientific community. Samples allocated for analysis are likely to be small sections of individual collectors, therefore subdividing the materials must take place in a clean, well characterized way. A major focus of current research at JSC includes identifying and characterizing the contamination, waste, and alteration of the sample when using different subdividing, transport, and storage techniques and developing protocols for reducing their impact on the scientific integrity of the mission.

  2. Genesis of Ultra-High Pressure Garnet Pyroxenite in Orogenic Peridotites and its bearing on the Isotopic Chemical Heterogeneity in the Mantle Source of Oceanic Basalts

    NASA Astrophysics Data System (ADS)

    Varas Reus, María Isabel; Garrido, Carlos J.; Marchesi, Claudio; Bosch, Delphine; Hidas, Károly

    2017-04-01

    The genesis of ultra-high pressure (UHP) garnet pyroxenites in orogenic peridotite massifs and its implications on the formation of chemical heterogeneities in the mantle and on basalt petrogenesis are still not fully understood. Some UHP (diamond-bearing) garnet pyroxenites have isotopic, and major and trace element compositions similar to the recycled oceanic crustal component observed in oceanic basalts [1-6]. These pyroxenites hence provide an exceptional opportunity to investigate in situ the nature and scale of the Earth's mantle chemical heterogeneities. Here, we present an integrated geochemical study of UHP garnet pyroxenites from the Ronda (Betic Belt, S. Spain) and Beni Bousera (Rif Belt, N. Morocco) peridotite massifs. This investigation encompasses, in the same sample, bulk rock major and trace elements, as well as Sr-Nd-Pb-Hf isotopic analyses. According to their Al2O3 content, we classify UHP garnet pyroxenites into three groups that have distinct trace elements and Sr-Nd-Pb-Hf isotopic signatures. Group A pyroxenites (Al2O3: 15 - 17.5 wt. %) are characterized by low initial 87Sr/86Sr, relatively high 143Nd/144Nd, 206Pb/204Pb and 176Hf/177Hf ratios, and highly variable 207Pb/204Pb and 208Pb/204Pb ratios. Group B pyroxenites (Al2O3 < 14 wt. %) have isotopic signatures characterized by relatively high initial 87Sr/86Sr and low 143Nd/144Nd, 206Pb/204Pb and 176Hf/177Hf ratios. Group C pyroxenites (Al2O3 ˜ 15 wt. %) display relatively low initial 87Sr/86Sr and 206Pb/204Pb ratios, high 143Nd/144Nd and 176Hf/177Hf ratios, and 207Pb/204Pb and 208Pb/204Pb ratios similar to Group B pyroxenites. The major and trace element, and isotopic compositions of the studied Ronda and Beni Bousera UHP garnet pyroxenites lend support to the "Marble Cake Mantle" model [7] for the genesis of these pyroxenites. This model envisions the mantle source of oceanic basalts as a mélange of subducted, ancient oceanic crust —-represented by garnet pyroxenites in orogenic peridotites—- intimately mixed with peridotites by mantle convection. The present study reveals, however, that besides this exotic component of ancient recycled oceanic crust, the genesis of these pyroxenites requires a previously unnoticed component of recycled lower continental crust akin to the lower crustal section of the lithosphere where these UHP garnet pyroxenites now reside in. The results of this study provide a new recipe for the marble cake hypothesis for the genesis of UHP garnet pyroxenites in orogenic peridotites. Furthermore, it establishes a connection between the genesis of UHP pyroxenites, the composition of the continental crust and the generation of Earth's mantle heterogeneities. References: [1] Pearson, D. G., Davies, G. R. & Nixon, P. H. (1993). Geochemical constraints on the petrogenesis of diamond facies pyroxenites from the Beni Bousera peridotite massif, North Morocco. Journal of Petrology 34, 125-172. [2] Blichert-Toft, J., Albarède, F. & Kornprobst, J. (1999). Lu-Hf Isotope systematics of garnet pyroxenites from Beni Bousera, Morocco: implications for basalt origin. Science 283, 1303-1306. [3] Garrido, C. J. & Bodinier, J. L. (1999). Diversity of mafic rocks in the Ronda peridotite: Evidence for pervasive melt-rock reaction during heating of subcontinental lithosphere by upwelling asthenosphere. Journal of Petrology 40, 729-754. [4] Marchesi, C., Garrido, C.J., Bosch, D., Bodinier, J.-L., Gervilla, F., Hidas, K., 2013. Mantle refertilization by melts of crustal-derived garnet pyroxenite: Evidence from the Ronda peridotite massif, southern Spain. Earth and Planetary Science Letters 362, 66-75. doi: 10.1016/j.epsl.2012.11.047. [5] Marchesi, C., Dale, C.W., Garrido, C.J., Pearson, D.G., Bosch, D., Bodinier, J.-L., Gervilla, F., Hidas, K., 2014. Fractionation of highly siderophile elements in refertilized mantle: Implications for the Os isotope composition of basalts. Earth and Planetary Science Letters 400, 33-44. doi: 10.1016/j.epsl.2014.05.025 [6] Montanini, A. & Tribuzio, R. (2015). Evolution of recycled crust within the mantle: Constraints from the garnet pyroxenites of the External Ligurian ophiolites (northern Apennines, Italy). Geology 43, 911-914. [7] Allègre, C. J. & Turcotte, D. L. (1986). Implications of a two-component marble-cake mantle. Nature 323, 123-127.

  3. Multi-element RIMS Analysis of Genesis Solar Wind Collectors

    NASA Astrophysics Data System (ADS)

    Veryovkin, I. V.; Tripa, C. E.; Zinovev, A. V.; King, B. V.; Pellin, M. J.; Burnett, D. S.

    2009-12-01

    The samples of Solar Wind (SW) delivered by the NASA Genesis mission, present significant challenges for surface analytical techniques, in part due to severe terrestrial contamination of the samples on reentry, in part due to the ultra-shallow and diffused ion implants in the SW collector materials. We are performing measurements of metallic elements in the Genesis collectors using Resonance Ionization Mass Spectrometry (RIMS), an ultra-sensitive analytical method capable of detecting SW in samples with lateral dimensions of only a few mm and at concentrations from above one ppm to below one ppt. Since our last report at 2008 AGU Fall Meeting, we have (a) developed and tested new resonance ionization schemes permitting simultaneous measurements of up to three (Ca, Cr, and Mg) elements, and (b) improved reproducibility and accuracy of our RIMS analyses for SW-like samples (i.e. shallow ion implants) by developing and implementing an optimized set of new analytical protocols. This is important since the quality of scientific results from the Genesis mission critically depends on the accuracy of analytical techniques. In this work, we report on simultaneous RIMS measurements of Ca and Cr performed on two silicon SW collector samples, (#60179 and #60476). First, we have conducted test experiments with 3×1013 at/cm2 52Cr and 44Ca implants in silicon to evaluate the accuracy of our quantitative analyses. Implant fluencies were measured by RIMS to be 2.73×1013 and 2.71×1013 at/cm2 for 52Cr and 44Ca, respectively, which corresponds to an accuracy of ≈10%. Using the same implanted wafer as a reference, we conducted RIMS analyses of the Genesis samples: 3 spots on #60179 and 4 spots on #60476. The elemental SW fluencies expected for Cr and Ca are 2.95×1010 and 1.33×1011 at/cm2 , respectively. Our measurements of 52Cr yielded 3.0±0.6×1011 at/cm2 and 5.1±4.1×1010 at/cm2 for #60179 and #60476, respectively. For 40Ca, SW fluencies of 1.39±0.70×1011 at/cm2 in #60179 and 3.6±2.5×1013 at/cm2 in #60476 were measured. Thus, only one element in each sample showed reasonable agreement with the expected values, Ca in #60179 and Cr in #60476. However the cleaning procedures applied to these samples were different: #60179 was only Megasonicated in ultra-pure water, while #60476 was subjected to longer Megasonication and an RCA cleaning procedure involving multiple rinsing steps with acid solutions. It is apparent that the surface contamination and cleaning procedures influenced the results of our measurements. We will present these experimental results and discuss procedures - including improved sample cleaning, dual-beam high resolution sputter depth profiling from front and back sides of the sample, and modeling of near-surface impurity transport - aimed at improving the accuracy of determination of elemental abundances by ion sputtering based analytical methods. This work is supported by NASA through a grant NNH08AH761 and by UChicago Argonne, LLC, under contract No. DE-AC02-06CH11357.

  4. Ultramafics-Hydrothermalism-Hydrogenesis-HyperSLiME (UltraH3) Linkage is a key for Occurrence of Last Universal Common Ancestral (LUCA) Community: Where is it, Lost City or Kairei (Rainbow)?

    NASA Astrophysics Data System (ADS)

    Takai, K.; Inagaki, F.; Nakamura, K.; Suzuki, K.; Kumagai, H.

    2005-12-01

    Deep-sea hydrothermal system has been recognized one of the most plausible places for origin of life in this planet. This hypothesis has been supported by evidences from multidisciplinary scientific fields. In geology, it has been demonstrated that the potentially most ancient microbial fossils are retrieved from the paleoenvironment, that might be related with deep-sea hydrothermal systems in the Archean. Chemical reactions suggesting prebiotic chemical evolution (synthesis of amino acids, nucleic acids and hydrocarbon, and polymerization of these molecules) are observed under the simulated physical and chemical conditions of the deep-sea hydrothermal vents in the laboratory. In addition, phylogenetic analyses of all the lives in this planet have clearly revealed that hyperthermophiles inhabiting deep-sea hydrothermal systems represent the deepest lineage of the life. Supposed that the Archean deep-sea hydrothermal system hosted the origin of life, what was the first life? We are pursuing the energy metabolism of our last universal common ancestor (LUCA) and the environmental settings hosting the LUCA. It is definitely expected that the genesis of LUCA occurred at high temperatures of locally organics-rich microenvironment around deep-sea hydrothermal field and the first energy metabolism depended on fermentation of simple amino acids, organic acids and sugars. However, these organics were immediately consumed by the hyperthermophilic LUCA activity. Inheritance of the LUCA needed to evolve the energy and carbon acquisitions to more stable and efficient mode. Chemolithoautotrophy might be the best because a plenty of reductive gas components were always provided by the hydrothermal activity. Hyperthermophilic chemolithoautotrophs could serve as the primary producers and could foster the heterotrophic fellows. This was the genesis of the last universal common ancestral (LUCA) community of life. We hypothesize that the LUCA community was metabolically approximated to hyperthermophilic subsurface lithoautotrophic microbial ecosystem (HyperSLiME) currently discovered beneath the Central Indian Ridge hydrothermal field. The environmental settings for the occurrence of HyperSLiME are now being characterized and an important linkage among the occurrence of HyperSLiME, extraordinary amount of hydrogen in the hydrothermal fluids and ultramfics-hosted hydrothermal systems is proposed. This ultramafics-hydrothermalism-hydrogen-HyperSLiME (UltraH3) linkage is very likely a key for the genesis of the LUCA community. We would like to discuss the possible UltraH3 linkage in the Archean earth. In addition, we would like to discuss which of modern deep-sea hydrothermal systems is the most plausible proxy for the Archean LUCA habitats.

  5. A novel mechanism for creating double pulsars

    NASA Technical Reports Server (NTRS)

    Sigurdsson, Steinn; Hernquist, Lars

    1992-01-01

    Simulations of encounters between pairs of hard binaries, each containing a neutron star and a main-sequence star, reveal a new formation mechanism for double pulsars in dense cores of globular clusters. In many cases, the two normal stars are disrupted to form a common envelope around the pair of neutron stars, both of which will be spun up to become millisecond pulsars. We predict that a new class of pulsars, double millisecond pulsars, will be discovered in the cores of dense globular clusters. The genesis proceeds through a short-lived double-core common envelope phase, with the envelope ejected in a fast wind. It is possible that the progenitor may also undergo a double X-ray binary phase. Any circular, short-period double pulsar found in the galaxy would necessarily come from disrupted disk clusters, unlike Hulse-Taylor class pulsars or low-mass X-ray binaries which may be ejected from clusters or formed in the galaxy.

  6. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Flechsig, U.; Follath, R.; Reiche, S.

    PHASE is a software tool for physical optics simulation based on the stationary phase approximation method. The code is under continuous development since about 20 years and has been used for instance for fundamental studies and ray tracing of various beamlines at the Swiss Light Source. Along with the planning for SwissFEL a new hard X-ray free electron laser under construction, new features have been added to permit practical performance predictions including diffraction effects which emerge with the fully coherent source. We present the application of the package on the example of the ARAMIS 1 beamline at SwissFEL. The X-raymore » pulse calculated with GENESIS and given as an electrical field distribution has been propagated through the beamline to the sample position. We demonstrate the new features of PHASE like the treatment of measured figure errors, apertures and coatings of the mirrors and the application of Fourier optics propagators for free space propagation.« less

  7. Early-Holocene warming in Beringia and its mediation by sea-level and vegetation changes

    USGS Publications Warehouse

    Bartlein, P.J.; Edwards, M.E.; Hostetler, Steven W.; Shafer, Sarah; Anderson, P.M.; Brubaker, L. B; Lozhkin, A. V

    2015-01-01

    Arctic land-cover changes induced by recent global climate change (e.g., expansion of woody vegetation into tundra and effects of permafrost degradation) are expected to generate further feedbacks to the climate system. Past changes can be used to assess our understanding of feedback mechanisms through a combination of process modeling and paleo-observations. The subcontinental region of Beringia (northeastern Siberia, Alaska, and northwestern Canada) was largely ice-free at the peak of deglacial warming and experienced both major vegetation change and loss of permafrost when many arctic regions were still ice covered. The evolution of Beringian climate at this time was largely driven by global features, such as the amplified seasonal cycle of Northern Hemisphere insolation and changes in global ice volume and atmospheric composition, but changes in regional land-surface controls, such as the widespread development of thaw lakes, the replacement of tundra by deciduous forest or woodland, and the flooding of the Bering–Chukchi land bridge, were probably also important. We examined the sensitivity of Beringia's early Holocene climate to these regional-scale controls using a regional climate model (RegCM). Lateral and oceanic boundary conditions were provided by global climate simulations conducted using the GENESIS V2.01 atmospheric general circulation model (AGCM) with a mixed-layer ocean. We carried out two present-day simulations of regional climate – one with modern and one with 11 ka geography – plus another simulation for 6 ka. In addition, we performed five ~ 11 ka climate simulations, each driven by the same global AGCM boundary conditions: (i) 11 ka Control, which represents conditions just prior to the major transitions (exposed land bridge, no thaw lakes or wetlands, widespread tundra vegetation), (ii) sea-level rise, which employed present-day continental outlines, (iii) vegetation change, with deciduous needleleaf and deciduous broadleaf boreal vegetation types distributed as suggested by the paleoecological record, (iv) thaw lakes, which used the present-day distribution of lakes and wetlands, and (v) post-11 ka All, incorporating all boundary conditions changed in experiments (ii)–(iv). We find that regional-scale controls strongly mediate the climate responses to changes in the large-scale controls, amplifying them in some cases, damping them in others, and, overall, generating considerable spatial heterogeneity in the simulated climate changes. The change from tundra to deciduous woodland produces additional widespread warming in spring and early summer over that induced by the 11 ka insolation regime alone, and lakes and wetlands produce modest and localized cooling in summer and warming in winter. The greatest effect is the flooding of the land bridge and shelves, which produces generally cooler conditions in summer but warmer conditions in winter and is most clearly manifest on the flooded shelves and in eastern Beringia. By 6 ka continued amplification of the seasonal cycle of insolation and loss of the Laurentide ice sheet produce temperatures similar to or higher than those at 11 ka, plus a longer growing season.

  8. New York City Impact on Regional Heat Wave

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ortiz, Luis E.; Schoonen, Martin

    Abstract Extreme heat events are projected to increase in magnitude and frequency throughout this century due to increasing global temperatures, making it critically important to acquire improved understanding of their genesis and interactions with large cities. This study presents an application of the factor separation method to assess combined impacts of a synoptic scale heat wave, urban land cover, and urban energy and momentum fluxes on temperatures and winds over New York City via use of high resolution simulations (1 km grid spacing) with an urbanized WRF model. Results showed that, while the heat wave had the largest contribution tomore » temperatures (> 8°C), urban surface factors matched it in highly urbanized areas. Surface factors matched this in highly urbanized areas during night and early morning hours, with contributions up to 5°C, when calm land breeze conditions result in a strong urban heat island. Positive interactions between all factors during morning and nighttime indicate urban heat island amplification of up to 4°C during the heat wave. Midtown Manhattan vertical cross-sections, where urban canopies are most dense, showed a change in the sign (from positive to negative) of the contribution of the urban fluxes between night and day below 500 m, possibly due to radiation blocking and increased thermal storage by buildings as well as frictional effects opposing the incoming warm air.« less

  9. New York City Impact on Regional Heat Wave

    DOE PAGES

    Ortiz, Luis E.; Schoonen, Martin

    2018-04-01

    Abstract Extreme heat events are projected to increase in magnitude and frequency throughout this century due to increasing global temperatures, making it critically important to acquire improved understanding of their genesis and interactions with large cities. This study presents an application of the factor separation method to assess combined impacts of a synoptic scale heat wave, urban land cover, and urban energy and momentum fluxes on temperatures and winds over New York City via use of high resolution simulations (1 km grid spacing) with an urbanized WRF model. Results showed that, while the heat wave had the largest contribution tomore » temperatures (> 8°C), urban surface factors matched it in highly urbanized areas. Surface factors matched this in highly urbanized areas during night and early morning hours, with contributions up to 5°C, when calm land breeze conditions result in a strong urban heat island. Positive interactions between all factors during morning and nighttime indicate urban heat island amplification of up to 4°C during the heat wave. Midtown Manhattan vertical cross-sections, where urban canopies are most dense, showed a change in the sign (from positive to negative) of the contribution of the urban fluxes between night and day below 500 m, possibly due to radiation blocking and increased thermal storage by buildings as well as frictional effects opposing the incoming warm air.« less

  10. Villification of the gut

    NASA Astrophysics Data System (ADS)

    Tallinen, Tuomas; Shyer, Amy E.; Tabin, Clifford J.; Mahadevan, L.

    2014-03-01

    The villi of the human and chick gut are formed in similar stepwise progressions, wherein the mesenchyme and attached epithelium first fold into longitudinal ridges, then a zigzag pattern, and lastly individual villi. We combine biological manipulations and quantitative modeling to show that these steps of villification depend on the sequential differentiation of the distinct smooth muscle layers of the gut, which restrict the expansion of the growing endoderm and mesenchyme, generating compressive stresses that lead to their buckling and folding. Our computational model incorporates measured elastic properties and growth rates in the developing gut, recapitulating the morphological patterns seen during villification in a variety of species. Our study provides a mechanical basis for the genesis of these epithelial protrusions that are essential for providing sufficient surface area for nutrient absorption.

  11. The model of the long-range effect in solids: Evolution of structure, clusters of internal boundaries, and their statistical descriptors

    NASA Astrophysics Data System (ADS)

    Herega, Alexander; Sukhanov, Volodymyr; Vyrovoy, Valery

    2017-12-01

    It is known that the multifocal mechanism of genesis of structure of heterogeneous materials provokes intensive formation of internal boundaries. In the present papers, the dependence of the structure and properties of material on the characteristic size and shape, the number and size distribution, and the character of interaction of individual internal boundaries and their clusters is studied. The limitation on the applicability of the material damage coefficient is established; the effective information descriptor of internal boundaries is proposed. An idea of the effect of long-range interaction in irradiated solids on the realization of the second-order phase transition is introduced; a phenomenological percolation model of the effect is proposed.

  12. On the Genesis of Reliability Models.

    DTIC Science & Technology

    1982-07-01

    dy1 fRi fI, where I: Y1 H,(yl~y2,t) = ex (tly) Irl(y2)11+ f ,ra(y2*(yl’))dyl’].(.9 The results, dH , = _r(y2*(y))H(y,y,,t)* dt H,(4rfjy 2 t) = eP...Press, 1971. 2. Payne, A. 0.: A reliability approach to the fatigue of structures. ASTM STP 511, pp. 106 - 155, 1972. 3. Diamond, P., and Payne, A. 0...Commonwealth Aircraft Corporation, Library Hawker de Havilland Aust. Pty. Ltd., Bankstown, Library Rolls-Royce of Australia Pty. Ltd., Mr. C. 0. A. Bailey

  13. Methods and tools to simulate the effect of economic instruments in complex water resources systems. Application to the Jucar river basin.

    NASA Astrophysics Data System (ADS)

    Lopez-Nicolas, Antonio; Pulido-Velazquez, Manuel

    2014-05-01

    The main challenge of the BLUEPRINT to safeguard Europe's water resources (EC, 2012) is to guarantee that enough good quality water is available for people's needs, the economy and the environment. In this sense, economic policy instruments such as water pricing policies and water markets can be applied to enhance efficient use of water. This paper presents a method based on hydro-economic tools to assess the effect of economic instruments on water resource systems. Hydro-economic models allow integrated analysis of water supply, demand and infrastructure operation at the river basin scale, by simultaneously combining engineering, hydrologic and economic aspects of water resources management. The method made use of the simulation and optimization hydroeconomic tools SIMGAMS and OPTIGAMS. The simulation tool SIMGAMS allocates water resources among the users according to priorities and operating rules, and evaluate economic scarcity costs of the system by using economic demand functions. The model's objective function is designed so that the system aims to meet the operational targets (ranked according to priorities) at each month while following the system operating rules. The optimization tool OPTIGAMS allocates water resources based on an economic efficiency criterion: maximize net benefits, or alternatively, minimizing the total water scarcity and operating cost of water use. SIMGAS allows to simulate incentive water pricing policies based on marginal resource opportunity costs (MROC; Pulido-Velazquez et al., 2013). Storage-dependent step pricing functions are derived from the time series of MROC values at a certain reservoir in the system. These water pricing policies are defined based on water availability in the system (scarcity pricing), so that when water storage is high, the MROC is low, while low storage (drought periods) will be associated to high MROC and therefore, high prices. We also illustrate the use of OPTIGAMS to simulate the effect of ideal water markets by economic optimization, without considering the potential effect of transaction costs. These methods and tools have been applied to the Jucar River basin (Spain). The results show the potential of economic instruments in setting incentives for a more efficient management of water resources systems. Acknowledgments: The study has been partially supported by the European Community 7th Framework Project (GENESIS project, n. 226536), SAWARES (Plan Nacional I+D+i 2008-2011, CGL2009-13238-C02-01 and C02-02), SCARCE (Consolider-Ingenio 2010 CSD2009-00065) of the Spanish Ministry of Economy and Competitiveness; and EC 7th Framework Project ENHANCE (n. 308438) Reference: Pulido-Velazquez, M., Alvarez-Mendiola, E., and Andreu, J., 2013. Design of Efficient Water Pricing Policies Integrating Basinwide Resource Opportunity Costs. J. Water Resour. Plann. Manage., 139(5): 583-592.

  14. Genesis of Preeclampsia: An Epidemiological Approach

    PubMed Central

    Salvador-Moysén, Jaime; Martínez-López, Yolanda; Ramírez-Aranda, José M.; Aguilar-Durán, Marisela; Terrones-González, Alberto

    2012-01-01

    There are analyzed some of the main aspects related to the causality of preeclampsia, privileging two types of models: the clinic model and the epidemiologic model, first one represented by the hypothesis of the reduced placental perfusion and the second one considering the epidemiologic findings related to the high levels of psychosocial stress and its association with preeclampsia. It is reasoned out the relevance of raising the causality of the disease from an interdisciplinary perspective, integrating the valuable information generated from both types, clinical and epidemiologic, and finally a tentative explanatory model of preeclampsia is proposed, the subclinical and sociocultural aspects that predispose and trigger the disease are emphasized making aspects to stand out: the importance of reduced placental perfusion as an indicator of individual risk, and the high levels of physiological stress, as a result of the unfavorable conditions of the psychosocial surroundings (indicator of population risk) of the pregnant women. PMID:22462008

  15. Theoretical Commitment and Implicit Knowledge: Why Anomalies do not Trigger Learning

    NASA Astrophysics Data System (ADS)

    Ohlsson, Stellan

    A theory consists of a mental model, laws that specify parameters of the model and one or more explanatory schemas. Models represent by being isomorphic to real systems. To explain an event is to reenact its genesis by executing the relevant model in the mind's eye. Schemas capture recurring structural features of explanations. To subscribe to a theory is to be committed to explaining a particular class of events with that theory (and nothing else). Given theoretical commitment, an anomaly, i.e., an event that cannot be explained, is an occasion for theory change, but in the absence of commitment, the response is instead to exclude the anomalous event from the domain of application of the theory. Lay people and children hold their theories implicitly and hence without commitment. These observations imply that the analogy between scientist's theories and children's knowledge is valid, but that the analogy between theory change and learning is not.

  16. Control of birhythmicity: A self-feedback approach

    NASA Astrophysics Data System (ADS)

    Biswas, Debabrata; Banerjee, Tanmoy; Kurths, Jürgen

    2017-06-01

    Birhythmicity occurs in many natural and artificial systems. In this paper, we propose a self-feedback scheme to control birhythmicity. To establish the efficacy and generality of the proposed control scheme, we apply it on three birhythmic oscillators from diverse fields of natural science, namely, an energy harvesting system, the p53-Mdm2 network for protein genesis (the OAK model), and a glycolysis model (modified Decroly-Goldbeter model). Using the harmonic decomposition technique and energy balance method, we derive the analytical conditions for the control of birhythmicity. A detailed numerical bifurcation analysis in the parameter space establishes that the control scheme is capable of eliminating birhythmicity and it can also induce transitions between different forms of bistability. As the proposed control scheme is quite general, it can be applied for control of several real systems, particularly in biochemical and engineering systems.

  17. Timescales for the evolution of oxygen isotope compositions in the solar nebula

    NASA Astrophysics Data System (ADS)

    Lyons, J. R.; Bergin, E. A.; Ciesla, F. J.; Davis, A. M.; Desch, S. J.; Hashizume, K.; Lee, J.-E.

    2009-09-01

    We review two models for the origin of the calcium-, aluminum-rich inclusion (CAI) oxygen isotope mixing line in the solar nebula: (1) CO self-shielding, and (2) chemical mass-independent fractionation (MIF). We consider the timescales associated with formation of an isotopically anomalous water reservoir derived from CO self-shielding, and also the vertical and radial transport timescales of gas and solids in the nebula. The timescales for chemical MIF are very rapid. CO self-shielding models predict that the Sun has Δ 17O SMOW ˜ -20‰ (Clayton, 2002), and chemical mass-independent fractionation models predict Δ 17O SMOW ˜0‰. Preliminary Genesis results have been reported by McKeegan et al. (McKeegan K. D., Coath C. D., Heber, V., Jarzebinski G., Kallio A. P., Kunihiro T., Mao P. H. and Burnett D. S. (2008b) The oxygen isotopic composition of captured solar wind: first results from the Genesis. EOS Trans. AGU 89(53), Fall Meet. Suppl., P42A-07 (abstr)) and yield a Δ 17O SMOW of ˜ -25‰, consistent with a CO self-shielding scenario. Assuming that subsequent Genesis analyses support the preliminary results, it then remains to determine the relative contributions of CO self-shielding from the X-point, the surface of the solar nebula and the parent molecular cloud. The relative formation ages of chondritic components can be related to several timescales in the self-shielding theories. Most importantly the age difference of ˜1-3 My between CAIs and chondrules is consistent with radial transport from the outer solar nebula (>10 AU) to the meteorite-forming region, which supports both the nebular surface and parent cloud self-shielding scenarios. An elevated radiation field intensity is predicted by the surface shielding model, and yields substantial CO photolysis (˜50%) on timescales of 0.1-1 My. An elevated radiation field is also consistent with the parent cloud model. The elevated radiation intensities may indicate solar nebula birth in a medium to large cluster, and may be consistent with the injection of 60Fe from a nearby supernova and with the photoevaporative truncation of the solar nebula at KBO orbital distances (˜47 AU). CO self-shielding is operative at the X-point even when H 2 absorption is included, but it is not yet clear whether the self-shielding signature can be imparted to silicates. A simple analysis of diffusion times shows that oxygen isotope exchange between 16O-depleted nebular H 2O and chondrules during chondrule formation events is rapid (˜minutes), but is also expected to be rapid for most components of CAIs, with the exception of spinel. This is consistent with the observation that spinel grains are often the most 16O-rich component of CAIs, but is only broadly consistent with the greater degree of exchange in other CAI components. Preliminary disk model calculations of self-shielding by N 2 demonstrate that large δ 15N enrichments (˜ +800‰) are possible in HCN formed by reaction of N atoms with organic radicals (e.g., CH 2), which may account for 15N-rich hotspots observed in lithic clasts in some carbonaceous chondrites and which lends support to the CO self-shielding model for oxygen isotopes.

  18. Plan for Subdividing Genesis Mission Diamond-on-Silicon 60000 Solar Wind Collector

    NASA Technical Reports Server (NTRS)

    Burkett, Patti J.; Allton, J. A.; Clemett, S. J.; Gonzales, C. P.; Lauer, H. V., Jr.; Nakamura-Messenger, K.; Rodriquez, M. C.; See, T. H.; Sutter, B.

    2013-01-01

    NASA's Genesis solar wind sample return mission experienced an off nominal landing resulting in broken, albeit useful collectors. Sample 60000 from the collector is comprised of diamond-like-carbon film on a float zone (FZ) silicon wafer substrate Diamond-on-Silicon (DOS), and is highly prized for its higher concentration of solar wind (SW) atoms. A team of scientist at the Johnson Space Center was charged with determining the best, nondestructive and noncontaminating method to subdivide the specimen that would result in a 1 sq. cm subsample for allocation and analysis. Previous work included imaging of the SW side of 60000, identifying the crystallographic orientation of adjacent fragments, and devising an initial cutting plan.

  19. Scale-invariant fluctuations from Galilean genesis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Yi; Brandenberger, Robert, E-mail: wangyi@physics.mcgill.ca, E-mail: rhb@physics.mcgill.ca

    2012-10-01

    We study the spectrum of cosmological fluctuations in scenarios such as Galilean Genesis \\cite(Nicolis) in which a spectator scalar field acquires a scale-invariant spectrum of perturbations during an early phase which asymptotes in the far past to Minkowski space-time. In the case of minimal coupling to gravity and standard scalar field Lagrangian, the induced curvature fluctuations depend quadratically on the spectator field and are hence non-scale-invariant and highly non-Gaussian. We show that if higher dimensional operators (the same operators that lead to the η-problem for inflation) are considered, a linear coupling between background and spectator field fluctuations is induced whichmore » leads to scale-invariant and Gaussian curvature fluctuations.« less

  20. [Networks and genesis of living beings: epistemologic perspectives].

    PubMed

    Perru, Olivier

    2007-01-01

    Our paper focuses on Stuart Kauffman's theory from 1993 to 2004. Kauffman is looking for an explanation of the genesis of living beings by genetic networks. From interactions to cell types, Kauffman's viewpoint is concerned with differentiation and self-organization as network's properties. His approach of morphogenetic processes is interesting but it is insufficient. According to Sole, Fernandez and Kauffman [2003], networks would give an explanation of the diversity in patterns and cell types. Some other authors [as Perkins et al., 2004] consider that it is necessary to explore interactions, not with logical methods only, but non-linear systems too. Network's structure is related to biological diversity. It supposes genes' power's mediators within the cells and between them.

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