Sample records for genetic algorithm experimental

  1. Flexible Space-Filling Designs for Complex System Simulations

    DTIC Science & Technology

    2013-06-01

    interior of the experimental region and cannot fit higher-order models. We present a genetic algorithm that constructs space-filling designs with...Computer Experiments, Design of Experiments, Genetic Algorithm , Latin Hypercube, Response Surface Methodology, Nearly Orthogonal 15. NUMBER OF PAGES 147...experimental region and cannot fit higher-order models. We present a genetic algorithm that constructs space-filling designs with minimal correlations

  2. Efficient experimental design of high-fidelity three-qubit quantum gates via genetic programming

    NASA Astrophysics Data System (ADS)

    Devra, Amit; Prabhu, Prithviraj; Singh, Harpreet; Arvind; Dorai, Kavita

    2018-03-01

    We have designed efficient quantum circuits for the three-qubit Toffoli (controlled-controlled-NOT) and the Fredkin (controlled-SWAP) gate, optimized via genetic programming methods. The gates thus obtained were experimentally implemented on a three-qubit NMR quantum information processor, with a high fidelity. Toffoli and Fredkin gates in conjunction with the single-qubit Hadamard gates form a universal gate set for quantum computing and are an essential component of several quantum algorithms. Genetic algorithms are stochastic search algorithms based on the logic of natural selection and biological genetics and have been widely used for quantum information processing applications. We devised a new selection mechanism within the genetic algorithm framework to select individuals from a population. We call this mechanism the "Luck-Choose" mechanism and were able to achieve faster convergence to a solution using this mechanism, as compared to existing selection mechanisms. The optimization was performed under the constraint that the experimentally implemented pulses are of short duration and can be implemented with high fidelity. We demonstrate the advantage of our pulse sequences by comparing our results with existing experimental schemes and other numerical optimization methods.

  3. Estimating the solute transport parameters of the spatial fractional advection-dispersion equation using Bees Algorithm

    NASA Astrophysics Data System (ADS)

    Mehdinejadiani, Behrouz

    2017-08-01

    This study represents the first attempt to estimate the solute transport parameters of the spatial fractional advection-dispersion equation using Bees Algorithm. The numerical studies as well as the experimental studies were performed to certify the integrity of Bees Algorithm. The experimental ones were conducted in a sandbox for homogeneous and heterogeneous soils. A detailed comparative study was carried out between the results obtained from Bees Algorithm and those from Genetic Algorithm and LSQNONLIN routines in FracFit toolbox. The results indicated that, in general, the Bees Algorithm much more accurately appraised the sFADE parameters in comparison with Genetic Algorithm and LSQNONLIN, especially in the heterogeneous soil and for α values near to 1 in the numerical study. Also, the results obtained from Bees Algorithm were more reliable than those from Genetic Algorithm. The Bees Algorithm showed the relative similar performances for all cases, while the Genetic Algorithm and the LSQNONLIN yielded different performances for various cases. The performance of LSQNONLIN strongly depends on the initial guess values so that, compared to the Genetic Algorithm, it can more accurately estimate the sFADE parameters by taking into consideration the suitable initial guess values. To sum up, the Bees Algorithm was found to be very simple, robust and accurate approach to estimate the transport parameters of the spatial fractional advection-dispersion equation.

  4. Estimating the solute transport parameters of the spatial fractional advection-dispersion equation using Bees Algorithm.

    PubMed

    Mehdinejadiani, Behrouz

    2017-08-01

    This study represents the first attempt to estimate the solute transport parameters of the spatial fractional advection-dispersion equation using Bees Algorithm. The numerical studies as well as the experimental studies were performed to certify the integrity of Bees Algorithm. The experimental ones were conducted in a sandbox for homogeneous and heterogeneous soils. A detailed comparative study was carried out between the results obtained from Bees Algorithm and those from Genetic Algorithm and LSQNONLIN routines in FracFit toolbox. The results indicated that, in general, the Bees Algorithm much more accurately appraised the sFADE parameters in comparison with Genetic Algorithm and LSQNONLIN, especially in the heterogeneous soil and for α values near to 1 in the numerical study. Also, the results obtained from Bees Algorithm were more reliable than those from Genetic Algorithm. The Bees Algorithm showed the relative similar performances for all cases, while the Genetic Algorithm and the LSQNONLIN yielded different performances for various cases. The performance of LSQNONLIN strongly depends on the initial guess values so that, compared to the Genetic Algorithm, it can more accurately estimate the sFADE parameters by taking into consideration the suitable initial guess values. To sum up, the Bees Algorithm was found to be very simple, robust and accurate approach to estimate the transport parameters of the spatial fractional advection-dispersion equation. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. A genetic algorithm approach in interface and surface structure optimization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Jian

    The thesis is divided into two parts. In the first part a global optimization method is developed for the interface and surface structures optimization. Two prototype systems are chosen to be studied. One is Si[001] symmetric tilted grain boundaries and the other is Ag/Au induced Si(111) surface. It is found that Genetic Algorithm is very efficient in finding lowest energy structures in both cases. Not only existing structures in the experiments can be reproduced, but also many new structures can be predicted using Genetic Algorithm. Thus it is shown that Genetic Algorithm is a extremely powerful tool for the materialmore » structures predictions. The second part of the thesis is devoted to the explanation of an experimental observation of thermal radiation from three-dimensional tungsten photonic crystal structures. The experimental results seems astounding and confusing, yet the theoretical models in the paper revealed the physics insight behind the phenomena and can well reproduced the experimental results.« less

  6. Research and application of multi-agent genetic algorithm in tower defense game

    NASA Astrophysics Data System (ADS)

    Jin, Shaohua

    2018-04-01

    In this paper, a new multi-agent genetic algorithm based on orthogonal experiment is proposed, which is based on multi-agent system, genetic algorithm and orthogonal experimental design. The design of neighborhood competition operator, orthogonal crossover operator, Son and self-learning operator. The new algorithm is applied to mobile tower defense game, according to the characteristics of the game, the establishment of mathematical models, and finally increases the value of the game's monster.

  7. Immune allied genetic algorithm for Bayesian network structure learning

    NASA Astrophysics Data System (ADS)

    Song, Qin; Lin, Feng; Sun, Wei; Chang, KC

    2012-06-01

    Bayesian network (BN) structure learning is a NP-hard problem. In this paper, we present an improved approach to enhance efficiency of BN structure learning. To avoid premature convergence in traditional single-group genetic algorithm (GA), we propose an immune allied genetic algorithm (IAGA) in which the multiple-population and allied strategy are introduced. Moreover, in the algorithm, we apply prior knowledge by injecting immune operator to individuals which can effectively prevent degeneration. To illustrate the effectiveness of the proposed technique, we present some experimental results.

  8. Superscattering of light optimized by a genetic algorithm

    NASA Astrophysics Data System (ADS)

    Mirzaei, Ali; Miroshnichenko, Andrey E.; Shadrivov, Ilya V.; Kivshar, Yuri S.

    2014-07-01

    We analyse scattering of light from multi-layer plasmonic nanowires and employ a genetic algorithm for optimizing the scattering cross section. We apply the mode-expansion method using experimental data for material parameters to demonstrate that our genetic algorithm allows designing realistic core-shell nanostructures with the superscattering effect achieved at any desired wavelength. This approach can be employed for optimizing both superscattering and cloaking at different wavelengths in the visible spectral range.

  9. Increasing Prediction the Original Final Year Project of Student Using Genetic Algorithm

    NASA Astrophysics Data System (ADS)

    Saragih, Rijois Iboy Erwin; Turnip, Mardi; Sitanggang, Delima; Aritonang, Mendarissan; Harianja, Eva

    2018-04-01

    Final year project is very important forgraduation study of a student. Unfortunately, many students are not seriouslydidtheir final projects. Many of studentsask for someone to do it for them. In this paper, an application of genetic algorithms to predict the original final year project of a studentis proposed. In the simulation, the data of the final project for the last 5 years is collected. The genetic algorithm has several operators namely population, selection, crossover, and mutation. The result suggest that genetic algorithm can do better prediction than other comparable model. Experimental results of predicting showed that 70% was more accurate than the previous researched.

  10. Image reconstruction through thin scattering media by simulated annealing algorithm

    NASA Astrophysics Data System (ADS)

    Fang, Longjie; Zuo, Haoyi; Pang, Lin; Yang, Zuogang; Zhang, Xicheng; Zhu, Jianhua

    2018-07-01

    An idea for reconstructing the image of an object behind thin scattering media is proposed by phase modulation. The optimized phase mask is achieved by modulating the scattered light using simulated annealing algorithm. The correlation coefficient is exploited as a fitness function to evaluate the quality of reconstructed image. The reconstructed images optimized from simulated annealing algorithm and genetic algorithm are compared in detail. The experimental results show that our proposed method has better definition and higher speed than genetic algorithm.

  11. Distributed genetic algorithms for the floorplan design problem

    NASA Technical Reports Server (NTRS)

    Cohoon, James P.; Hegde, Shailesh U.; Martin, Worthy N.; Richards, Dana S.

    1991-01-01

    Designing a VLSI floorplan calls for arranging a given set of modules in the plane to minimize the weighted sum of area and wire-length measures. A method of solving the floorplan design problem using distributed genetic algorithms is presented. Distributed genetic algorithms, based on the paleontological theory of punctuated equilibria, offer a conceptual modification to the traditional genetic algorithms. Experimental results on several problem instances demonstrate the efficacy of this method and indicate the advantages of this method over other methods, such as simulated annealing. The method has performed better than the simulated annealing approach, both in terms of the average cost of the solutions found and the best-found solution, in almost all the problem instances tried.

  12. Hybrid artificial bee colony algorithm for parameter optimization of five-parameter bidirectional reflectance distribution function model.

    PubMed

    Wang, Qianqian; Zhao, Jing; Gong, Yong; Hao, Qun; Peng, Zhong

    2017-11-20

    A hybrid artificial bee colony (ABC) algorithm inspired by the best-so-far solution and bacterial chemotaxis was introduced to optimize the parameters of the five-parameter bidirectional reflectance distribution function (BRDF) model. To verify the performance of the hybrid ABC algorithm, we measured BRDF of three kinds of samples and simulated the undetermined parameters of the five-parameter BRDF model using the hybrid ABC algorithm and the genetic algorithm, respectively. The experimental results demonstrate that the hybrid ABC algorithm outperforms the genetic algorithm in convergence speed, accuracy, and time efficiency under the same conditions.

  13. Genetic algorithms with memory- and elitism-based immigrants in dynamic environments.

    PubMed

    Yang, Shengxiang

    2008-01-01

    In recent years the genetic algorithm community has shown a growing interest in studying dynamic optimization problems. Several approaches have been devised. The random immigrants and memory schemes are two major ones. The random immigrants scheme addresses dynamic environments by maintaining the population diversity while the memory scheme aims to adapt genetic algorithms quickly to new environments by reusing historical information. This paper investigates a hybrid memory and random immigrants scheme, called memory-based immigrants, and a hybrid elitism and random immigrants scheme, called elitism-based immigrants, for genetic algorithms in dynamic environments. In these schemes, the best individual from memory or the elite from the previous generation is retrieved as the base to create immigrants into the population by mutation. This way, not only can diversity be maintained but it is done more efficiently to adapt genetic algorithms to the current environment. Based on a series of systematically constructed dynamic problems, experiments are carried out to compare genetic algorithms with the memory-based and elitism-based immigrants schemes against genetic algorithms with traditional memory and random immigrants schemes and a hybrid memory and multi-population scheme. The sensitivity analysis regarding some key parameters is also carried out. Experimental results show that the memory-based and elitism-based immigrants schemes efficiently improve the performance of genetic algorithms in dynamic environments.

  14. A modified genetic algorithm with fuzzy roulette wheel selection for job-shop scheduling problems

    NASA Astrophysics Data System (ADS)

    Thammano, Arit; Teekeng, Wannaporn

    2015-05-01

    The job-shop scheduling problem is one of the most difficult production planning problems. Since it is in the NP-hard class, a recent trend in solving the job-shop scheduling problem is shifting towards the use of heuristic and metaheuristic algorithms. This paper proposes a novel metaheuristic algorithm, which is a modification of the genetic algorithm. This proposed algorithm introduces two new concepts to the standard genetic algorithm: (1) fuzzy roulette wheel selection and (2) the mutation operation with tabu list. The proposed algorithm has been evaluated and compared with several state-of-the-art algorithms in the literature. The experimental results on 53 JSSPs show that the proposed algorithm is very effective in solving the combinatorial optimization problems. It outperforms all state-of-the-art algorithms on all benchmark problems in terms of the ability to achieve the optimal solution and the computational time.

  15. On the suitability of different representations of solid catalysts for combinatorial library design by genetic algorithms.

    PubMed

    Gobin, Oliver C; Schüth, Ferdi

    2008-01-01

    Genetic algorithms are widely used to solve and optimize combinatorial problems and are more often applied for library design in combinatorial chemistry. Because of their flexibility, however, their implementation can be challenging. In this study, the influence of the representation of solid catalysts on the performance of genetic algorithms was systematically investigated on the basis of a new, constrained, multiobjective, combinatorial test problem with properties common to problems in combinatorial materials science. Constraints were satisfied by penalty functions, repair algorithms, or special representations. The tests were performed using three state-of-the-art evolutionary multiobjective algorithms by performing 100 optimization runs for each algorithm and test case. Experimental data obtained during the optimization of a noble metal-free solid catalyst system active in the selective catalytic reduction of nitric oxide with propene was used to build up a predictive model to validate the results of the theoretical test problem. A significant influence of the representation on the optimization performance was observed. Binary encodings were found to be the preferred encoding in most of the cases, and depending on the experimental test unit, repair algorithms or penalty functions performed best.

  16. Phase Reconstruction from FROG Using Genetic Algorithms[Frequency-Resolved Optical Gating

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Omenetto, F.G.; Nicholson, J.W.; Funk, D.J.

    1999-04-12

    The authors describe a new technique for obtaining the phase and electric field from FROG measurements using genetic algorithms. Frequency-Resolved Optical Gating (FROG) has gained prominence as a technique for characterizing ultrashort pulses. FROG consists of a spectrally resolved autocorrelation of the pulse to be measured. Typically a combination of iterative algorithms is used, applying constraints from experimental data, and alternating between the time and frequency domain, in order to retrieve an optical pulse. The authors have developed a new approach to retrieving the intensity and phase from FROG data using a genetic algorithm (GA). A GA is a generalmore » parallel search technique that operates on a population of potential solutions simultaneously. Operators in a genetic algorithm, such as crossover, selection, and mutation are based on ideas taken from evolution.« less

  17. Experimental Performance of a Genetic Algorithm for Airborne Strategic Conflict Resolution

    NASA Technical Reports Server (NTRS)

    Karr, David A.; Vivona, Robert A.; Roscoe, David A.; DePascale, Stephen M.; Consiglio, Maria

    2009-01-01

    The Autonomous Operations Planner, a research prototype flight-deck decision support tool to enable airborne self-separation, uses a pattern-based genetic algorithm to resolve predicted conflicts between the ownship and traffic aircraft. Conflicts are resolved by modifying the active route within the ownship s flight management system according to a predefined set of maneuver pattern templates. The performance of this pattern-based genetic algorithm was evaluated in the context of batch-mode Monte Carlo simulations running over 3600 flight hours of autonomous aircraft in en-route airspace under conditions ranging from typical current traffic densities to several times that level. Encountering over 8900 conflicts during two simulation experiments, the genetic algorithm was able to resolve all but three conflicts, while maintaining a required time of arrival constraint for most aircraft. Actual elapsed running time for the algorithm was consistent with conflict resolution in real time. The paper presents details of the genetic algorithm s design, along with mathematical models of the algorithm s performance and observations regarding the effectiveness of using complimentary maneuver patterns when multiple resolutions by the same aircraft were required.

  18. Experimental Performance of a Genetic Algorithm for Airborne Strategic Conflict Resolution

    NASA Technical Reports Server (NTRS)

    Karr, David A.; Vivona, Robert A.; Roscoe, David A.; DePascale, Stephen M.; Consiglio, Maria

    2009-01-01

    The Autonomous Operations Planner, a research prototype flight-deck decision support tool to enable airborne self-separation, uses a pattern-based genetic algorithm to resolve predicted conflicts between the ownship and traffic aircraft. Conflicts are resolved by modifying the active route within the ownship's flight management system according to a predefined set of maneuver pattern templates. The performance of this pattern-based genetic algorithm was evaluated in the context of batch-mode Monte Carlo simulations running over 3600 flight hours of autonomous aircraft in en-route airspace under conditions ranging from typical current traffic densities to several times that level. Encountering over 8900 conflicts during two simulation experiments, the genetic algorithm was able to resolve all but three conflicts, while maintaining a required time of arrival constraint for most aircraft. Actual elapsed running time for the algorithm was consistent with conflict resolution in real time. The paper presents details of the genetic algorithm's design, along with mathematical models of the algorithm's performance and observations regarding the effectiveness of using complimentary maneuver patterns when multiple resolutions by the same aircraft were required.

  19. Optimization of multicast optical networks with genetic algorithm

    NASA Astrophysics Data System (ADS)

    Lv, Bo; Mao, Xiangqiao; Zhang, Feng; Qin, Xi; Lu, Dan; Chen, Ming; Chen, Yong; Cao, Jihong; Jian, Shuisheng

    2007-11-01

    In this letter, aiming to obtain the best multicast performance of optical network in which the video conference information is carried by specified wavelength, we extend the solutions of matrix games with the network coding theory and devise a new method to solve the complex problems of multicast network switching. In addition, an experimental optical network has been testified with best switching strategies by employing the novel numerical solution designed with an effective way of genetic algorithm. The result shows that optimal solutions with genetic algorithm are accordance with the ones with the traditional fictitious play method.

  20. A Genetic Algorithm and Fuzzy Logic Approach for Video Shot Boundary Detection

    PubMed Central

    Thounaojam, Dalton Meitei; Khelchandra, Thongam; Singh, Kh. Manglem; Roy, Sudipta

    2016-01-01

    This paper proposed a shot boundary detection approach using Genetic Algorithm and Fuzzy Logic. In this, the membership functions of the fuzzy system are calculated using Genetic Algorithm by taking preobserved actual values for shot boundaries. The classification of the types of shot transitions is done by the fuzzy system. Experimental results show that the accuracy of the shot boundary detection increases with the increase in iterations or generations of the GA optimization process. The proposed system is compared to latest techniques and yields better result in terms of F1score parameter. PMID:27127500

  1. Research on rolling element bearing fault diagnosis based on genetic algorithm matching pursuit

    NASA Astrophysics Data System (ADS)

    Rong, R. W.; Ming, T. F.

    2017-12-01

    In order to solve the problem of slow computation speed, matching pursuit algorithm is applied to rolling bearing fault diagnosis, and the improvement are conducted from two aspects that are the construction of dictionary and the way to search for atoms. To be specific, Gabor function which can reflect time-frequency localization characteristic well is used to construct the dictionary, and the genetic algorithm to improve the searching speed. A time-frequency analysis method based on genetic algorithm matching pursuit (GAMP) algorithm is proposed. The way to set property parameters for the improvement of the decomposition results is studied. Simulation and experimental results illustrate that the weak fault feature of rolling bearing can be extracted effectively by this proposed method, at the same time, the computation speed increases obviously.

  2. A Parallel Genetic Algorithm for Automated Electronic Circuit Design

    NASA Technical Reports Server (NTRS)

    Lohn, Jason D.; Colombano, Silvano P.; Haith, Gary L.; Stassinopoulos, Dimitris; Norvig, Peter (Technical Monitor)

    2000-01-01

    We describe a parallel genetic algorithm (GA) that automatically generates circuit designs using evolutionary search. A circuit-construction programming language is introduced and we show how evolution can generate practical analog circuit designs. Our system allows circuit size (number of devices), circuit topology, and device values to be evolved. We present experimental results as applied to analog filter and amplifier design tasks.

  3. A Genetic-Based Scheduling Algorithm to Minimize the Makespan of the Grid Applications

    NASA Astrophysics Data System (ADS)

    Entezari-Maleki, Reza; Movaghar, Ali

    Task scheduling algorithms in grid environments strive to maximize the overall throughput of the grid. In order to maximize the throughput of the grid environments, the makespan of the grid tasks should be minimized. In this paper, a new task scheduling algorithm is proposed to assign tasks to the grid resources with goal of minimizing the total makespan of the tasks. The algorithm uses the genetic approach to find the suitable assignment within grid resources. The experimental results obtained from applying the proposed algorithm to schedule independent tasks within grid environments demonstrate the applicability of the algorithm in achieving schedules with comparatively lower makespan in comparison with other well-known scheduling algorithms such as, Min-min, Max-min, RASA and Sufferage algorithms.

  4. Ternary alloy material prediction using genetic algorithm and cluster expansion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chen, Chong

    2015-12-01

    This thesis summarizes our study on the crystal structures prediction of Fe-V-Si system using genetic algorithm and cluster expansion. Our goal is to explore and look for new stable compounds. We started from the current ten known experimental phases, and calculated formation energies of those compounds using density functional theory (DFT) package, namely, VASP. The convex hull was generated based on the DFT calculations of the experimental known phases. Then we did random search on some metal rich (Fe and V) compositions and found that the lowest energy structures were body centered cube (bcc) underlying lattice, under which we didmore » our computational systematic searches using genetic algorithm and cluster expansion. Among hundreds of the searched compositions, thirteen were selected and DFT formation energies were obtained by VASP. The stability checking of those thirteen compounds was done in reference to the experimental convex hull. We found that the composition, 24-8-16, i.e., Fe 3VSi 2 is a new stable phase and it can be very inspiring to the future experiments.« less

  5. Experimental optimization of directed field ionization

    NASA Astrophysics Data System (ADS)

    Liu, Zhimin Cheryl; Gregoric, Vincent C.; Carroll, Thomas J.; Noel, Michael W.

    2017-04-01

    The state distribution of an ensemble of Rydberg atoms is commonly measured using selective field ionization. The resulting time resolved ionization signal from a single energy eigenstate tends to spread out due to the multiple avoided Stark level crossings atoms must traverse on the way to ionization. The shape of the ionization signal can be modified by adding a perturbation field to the main field ramp. Here, we present experimental results of the manipulation of the ionization signal using a genetic algorithm. We address how both the genetic algorithm and the experimental parameters were adjusted to achieve an optimized result. This work was supported by the National Science Foundation under Grants No. 1607335 and No. 1607377.

  6. Improved Fractal Space Filling Curves Hybrid Optimization Algorithm for Vehicle Routing Problem.

    PubMed

    Yue, Yi-xiang; Zhang, Tong; Yue, Qun-xing

    2015-01-01

    Vehicle Routing Problem (VRP) is one of the key issues in optimization of modern logistics system. In this paper, a modified VRP model with hard time window is established and a Hybrid Optimization Algorithm (HOA) based on Fractal Space Filling Curves (SFC) method and Genetic Algorithm (GA) is introduced. By incorporating the proposed algorithm, SFC method can find an initial and feasible solution very fast; GA is used to improve the initial solution. Thereafter, experimental software was developed and a large number of experimental computations from Solomon's benchmark have been studied. The experimental results demonstrate the feasibility and effectiveness of the HOA.

  7. Improved Fractal Space Filling Curves Hybrid Optimization Algorithm for Vehicle Routing Problem

    PubMed Central

    Yue, Yi-xiang; Zhang, Tong; Yue, Qun-xing

    2015-01-01

    Vehicle Routing Problem (VRP) is one of the key issues in optimization of modern logistics system. In this paper, a modified VRP model with hard time window is established and a Hybrid Optimization Algorithm (HOA) based on Fractal Space Filling Curves (SFC) method and Genetic Algorithm (GA) is introduced. By incorporating the proposed algorithm, SFC method can find an initial and feasible solution very fast; GA is used to improve the initial solution. Thereafter, experimental software was developed and a large number of experimental computations from Solomon's benchmark have been studied. The experimental results demonstrate the feasibility and effectiveness of the HOA. PMID:26167171

  8. New optimization model for routing and spectrum assignment with nodes insecurity

    NASA Astrophysics Data System (ADS)

    Xuan, Hejun; Wang, Yuping; Xu, Zhanqi; Hao, Shanshan; Wang, Xiaoli

    2017-04-01

    By adopting the orthogonal frequency division multiplexing technology, elastic optical networks can provide the flexible and variable bandwidth allocation to each connection request and get higher spectrum utilization. The routing and spectrum assignment problem in elastic optical network is a well-known NP-hard problem. In addition, information security has received worldwide attention. We combine these two problems to investigate the routing and spectrum assignment problem with the guaranteed security in elastic optical network, and establish a new optimization model to minimize the maximum index of the used frequency slots, which is used to determine an optimal routing and spectrum assignment schemes. To solve the model effectively, a hybrid genetic algorithm framework integrating a heuristic algorithm into a genetic algorithm is proposed. The heuristic algorithm is first used to sort the connection requests and then the genetic algorithm is designed to look for an optimal routing and spectrum assignment scheme. In the genetic algorithm, tailor-made crossover, mutation and local search operators are designed. Moreover, simulation experiments are conducted with three heuristic strategies, and the experimental results indicate that the effectiveness of the proposed model and algorithm framework.

  9. Mobile transporter path planning

    NASA Technical Reports Server (NTRS)

    Baffes, Paul; Wang, Lui

    1990-01-01

    The use of a genetic algorithm (GA) for solving the mobile transporter path planning problem is investigated. The mobile transporter is a traveling robotic vehicle proposed for the space station which must be able to reach any point of the structure autonomously. Elements of the genetic algorithm are explored in both a theoretical and experimental sense. Specifically, double crossover, greedy crossover, and tournament selection techniques are examined. Additionally, the use of local optimization techniques working in concert with the GA are also explored. Recent developments in genetic algorithm theory are shown to be particularly effective in a path planning problem domain, though problem areas can be cited which require more research.

  10. Tag SNP selection via a genetic algorithm.

    PubMed

    Mahdevar, Ghasem; Zahiri, Javad; Sadeghi, Mehdi; Nowzari-Dalini, Abbas; Ahrabian, Hayedeh

    2010-10-01

    Single Nucleotide Polymorphisms (SNPs) provide valuable information on human evolutionary history and may lead us to identify genetic variants responsible for human complex diseases. Unfortunately, molecular haplotyping methods are costly, laborious, and time consuming; therefore, algorithms for constructing full haplotype patterns from small available data through computational methods, Tag SNP selection problem, are convenient and attractive. This problem is proved to be an NP-hard problem, so heuristic methods may be useful. In this paper we present a heuristic method based on genetic algorithm to find reasonable solution within acceptable time. The algorithm was tested on a variety of simulated and experimental data. In comparison with the exact algorithm, based on brute force approach, results show that our method can obtain optimal solutions in almost all cases and runs much faster than exact algorithm when the number of SNP sites is large. Our software is available upon request to the corresponding author.

  11. Optimised analytical models of the dielectric properties of biological tissue.

    PubMed

    Salahuddin, Saqib; Porter, Emily; Krewer, Finn; O' Halloran, Martin

    2017-05-01

    The interaction of electromagnetic fields with the human body is quantified by the dielectric properties of biological tissues. These properties are incorporated into complex numerical simulations using parametric models such as Debye and Cole-Cole, for the computational investigation of electromagnetic wave propagation within the body. These parameters can be acquired through a variety of optimisation algorithms to achieve an accurate fit to measured data sets. A number of different optimisation techniques have been proposed, but these are often limited by the requirement for initial value estimations or by the large overall error (often up to several percentage points). In this work, a novel two-stage genetic algorithm proposed by the authors is applied to optimise the multi-pole Debye parameters for 54 types of human tissues. The performance of the two-stage genetic algorithm has been examined through a comparison with five other existing algorithms. The experimental results demonstrate that the two-stage genetic algorithm produces an accurate fit to a range of experimental data and efficiently out-performs all other optimisation algorithms under consideration. Accurate values of the three-pole Debye models for 54 types of human tissues, over 500 MHz to 20 GHz, are also presented for reference. Copyright © 2017 IPEM. Published by Elsevier Ltd. All rights reserved.

  12. "Genetically Engineered" Nanoelectronics

    NASA Technical Reports Server (NTRS)

    Klimeck, Gerhard; Salazar-Lazaro, Carlos H.; Stoica, Adrian; Cwik, Thomas

    2000-01-01

    The quantum mechanical functionality of nanoelectronic devices such as resonant tunneling diodes (RTDs), quantum well infrared-photodetectors (QWIPs), quantum well lasers, and heterostructure field effect transistors (HFETs) is enabled by material variations on an atomic scale. The design and optimization of such devices requires a fundamental understanding of electron transport in such dimensions. The Nanoelectronic Modeling Tool (NEMO) is a general-purpose quantum device design and analysis tool based on a fundamental non-equilibrium electron transport theory. NEW was combined with a parallelized genetic algorithm package (PGAPACK) to evolve structural and material parameters to match a desired set of experimental data. A numerical experiment that evolves structural variations such as layer widths and doping concentrations is performed to analyze an experimental current voltage characteristic. The genetic algorithm is found to drive the NEMO simulation parameters close to the experimentally prescribed layer thicknesses and doping profiles. With such a quantitative agreement between theory and experiment design synthesis can be performed.

  13. Combinatorial optimization problem solution based on improved genetic algorithm

    NASA Astrophysics Data System (ADS)

    Zhang, Peng

    2017-08-01

    Traveling salesman problem (TSP) is a classic combinatorial optimization problem. It is a simplified form of many complex problems. In the process of study and research, it is understood that the parameters that affect the performance of genetic algorithm mainly include the quality of initial population, the population size, and crossover probability and mutation probability values. As a result, an improved genetic algorithm for solving TSP problems is put forward. The population is graded according to individual similarity, and different operations are performed to different levels of individuals. In addition, elitist retention strategy is adopted at each level, and the crossover operator and mutation operator are improved. Several experiments are designed to verify the feasibility of the algorithm. Through the experimental results analysis, it is proved that the improved algorithm can improve the accuracy and efficiency of the solution.

  14. Application of artificial neural networks and genetic algorithms to modeling molecular electronic spectra in solution

    NASA Astrophysics Data System (ADS)

    Lilichenko, Mark; Kelley, Anne Myers

    2001-04-01

    A novel approach is presented for finding the vibrational frequencies, Franck-Condon factors, and vibronic linewidths that best reproduce typical, poorly resolved electronic absorption (or fluorescence) spectra of molecules in condensed phases. While calculation of the theoretical spectrum from the molecular parameters is straightforward within the harmonic oscillator approximation for the vibrations, "inversion" of an experimental spectrum to deduce these parameters is not. Standard nonlinear least-squares fitting methods such as Levenberg-Marquardt are highly susceptible to becoming trapped in local minima in the error function unless very good initial guesses for the molecular parameters are made. Here we employ a genetic algorithm to force a broad search through parameter space and couple it with the Levenberg-Marquardt method to speed convergence to each local minimum. In addition, a neural network trained on a large set of synthetic spectra is used to provide an initial guess for the fitting parameters and to narrow the range searched by the genetic algorithm. The combined algorithm provides excellent fits to a variety of single-mode absorption spectra with experimentally negligible errors in the parameters. It converges more rapidly than the genetic algorithm alone and more reliably than the Levenberg-Marquardt method alone, and is robust in the presence of spectral noise. Extensions to multimode systems, and/or to include other spectroscopic data such as resonance Raman intensities, are straightforward.

  15. A Constrained Genetic Algorithm with Adaptively Defined Fitness Function in MRS Quantification

    NASA Astrophysics Data System (ADS)

    Papakostas, G. A.; Karras, D. A.; Mertzios, B. G.; Graveron-Demilly, D.; van Ormondt, D.

    MRS Signal quantification is a rather involved procedure and has attracted the interest of the medical engineering community, regarding the development of computationally efficient methodologies. Significant contributions based on Computational Intelligence tools, such as Neural Networks (NNs), demonstrated a good performance but not without drawbacks already discussed by the authors. On the other hand preliminary application of Genetic Algorithms (GA) has already been reported in the literature by the authors regarding the peak detection problem encountered in MRS quantification using the Voigt line shape model. This paper investigates a novel constrained genetic algorithm involving a generic and adaptively defined fitness function which extends the simple genetic algorithm methodology in case of noisy signals. The applicability of this new algorithm is scrutinized through experimentation in artificial MRS signals interleaved with noise, regarding its signal fitting capabilities. Although extensive experiments with real world MRS signals are necessary, the herein shown performance illustrates the method's potential to be established as a generic MRS metabolites quantification procedure.

  16. A Swarm Optimization Genetic Algorithm Based on Quantum-Behaved Particle Swarm Optimization.

    PubMed

    Sun, Tao; Xu, Ming-Hai

    2017-01-01

    Quantum-behaved particle swarm optimization (QPSO) algorithm is a variant of the traditional particle swarm optimization (PSO). The QPSO that was originally developed for continuous search spaces outperforms the traditional PSO in search ability. This paper analyzes the main factors that impact the search ability of QPSO and converts the particle movement formula to the mutation condition by introducing the rejection region, thus proposing a new binary algorithm, named swarm optimization genetic algorithm (SOGA), because it is more like genetic algorithm (GA) than PSO in form. SOGA has crossover and mutation operator as GA but does not need to set the crossover and mutation probability, so it has fewer parameters to control. The proposed algorithm was tested with several nonlinear high-dimension functions in the binary search space, and the results were compared with those from BPSO, BQPSO, and GA. The experimental results show that SOGA is distinctly superior to the other three algorithms in terms of solution accuracy and convergence.

  17. An Adaptive Immune Genetic Algorithm for Edge Detection

    NASA Astrophysics Data System (ADS)

    Li, Ying; Bai, Bendu; Zhang, Yanning

    An adaptive immune genetic algorithm (AIGA) based on cost minimization technique method for edge detection is proposed. The proposed AIGA recommends the use of adaptive probabilities of crossover, mutation and immune operation, and a geometric annealing schedule in immune operator to realize the twin goals of maintaining diversity in the population and sustaining the fast convergence rate in solving the complex problems such as edge detection. Furthermore, AIGA can effectively exploit some prior knowledge and information of the local edge structure in the edge image to make vaccines, which results in much better local search ability of AIGA than that of the canonical genetic algorithm. Experimental results on gray-scale images show the proposed algorithm perform well in terms of quality of the final edge image, rate of convergence and robustness to noise.

  18. Determination of Cole-Cole parameters using only the real part of electrical impedivity measurements.

    PubMed

    Miranda, David A; Rivera, S A López

    2008-05-01

    An algorithm is presented to determine the Cole-Cole parameters of electrical impedivity using only measurements of its real part. The algorithm is based on two multi-fold direct inversion methods for the Cole-Cole and Debye equations, respectively, and a genetic algorithm for the optimization of the mean square error between experimental and calculated data. The algorithm has been developed to obtain the Cole-Cole parameters from experimental data, which were used to screen cervical intra-epithelial neoplasia. The proposed algorithm was compared with different numerical integrations of the Kramers-Kronig relation and the result shows that this algorithm is the best. A high immunity to noise was obtained.

  19. A synthetic genetic edge detection program.

    PubMed

    Tabor, Jeffrey J; Salis, Howard M; Simpson, Zachary Booth; Chevalier, Aaron A; Levskaya, Anselm; Marcotte, Edward M; Voigt, Christopher A; Ellington, Andrew D

    2009-06-26

    Edge detection is a signal processing algorithm common in artificial intelligence and image recognition programs. We have constructed a genetically encoded edge detection algorithm that programs an isogenic community of E. coli to sense an image of light, communicate to identify the light-dark edges, and visually present the result of the computation. The algorithm is implemented using multiple genetic circuits. An engineered light sensor enables cells to distinguish between light and dark regions. In the dark, cells produce a diffusible chemical signal that diffuses into light regions. Genetic logic gates are used so that only cells that sense light and the diffusible signal produce a positive output. A mathematical model constructed from first principles and parameterized with experimental measurements of the component circuits predicts the performance of the complete program. Quantitatively accurate models will facilitate the engineering of more complex biological behaviors and inform bottom-up studies of natural genetic regulatory networks.

  20. A Synthetic Genetic Edge Detection Program

    PubMed Central

    Tabor, Jeffrey J.; Salis, Howard; Simpson, Zachary B.; Chevalier, Aaron A.; Levskaya, Anselm; Marcotte, Edward M.; Voigt, Christopher A.; Ellington, Andrew D.

    2009-01-01

    Summary Edge detection is a signal processing algorithm common in artificial intelligence and image recognition programs. We have constructed a genetically encoded edge detection algorithm that programs an isogenic community of E.coli to sense an image of light, communicate to identify the light-dark edges, and visually present the result of the computation. The algorithm is implemented using multiple genetic circuits. An engineered light sensor enables cells to distinguish between light and dark regions. In the dark, cells produce a diffusible chemical signal that diffuses into light regions. Genetic logic gates are used so that only cells that sense light and the diffusible signal produce a positive output. A mathematical model constructed from first principles and parameterized with experimental measurements of the component circuits predicts the performance of the complete program. Quantitatively accurate models will facilitate the engineering of more complex biological behaviors and inform bottom-up studies of natural genetic regulatory networks. PMID:19563759

  1. Performance impact of mutation operators of a subpopulation-based genetic algorithm for multi-robot task allocation problems.

    PubMed

    Liu, Chun; Kroll, Andreas

    2016-01-01

    Multi-robot task allocation determines the task sequence and distribution for a group of robots in multi-robot systems, which is one of constrained combinatorial optimization problems and more complex in case of cooperative tasks because they introduce additional spatial and temporal constraints. To solve multi-robot task allocation problems with cooperative tasks efficiently, a subpopulation-based genetic algorithm, a crossover-free genetic algorithm employing mutation operators and elitism selection in each subpopulation, is developed in this paper. Moreover, the impact of mutation operators (swap, insertion, inversion, displacement, and their various combinations) is analyzed when solving several industrial plant inspection problems. The experimental results show that: (1) the proposed genetic algorithm can obtain better solutions than the tested binary tournament genetic algorithm with partially mapped crossover; (2) inversion mutation performs better than other tested mutation operators when solving problems without cooperative tasks, and the swap-inversion combination performs better than other tested mutation operators/combinations when solving problems with cooperative tasks. As it is difficult to produce all desired effects with a single mutation operator, using multiple mutation operators (including both inversion and swap) is suggested when solving similar combinatorial optimization problems.

  2. A Distributed Parallel Genetic Algorithm of Placement Strategy for Virtual Machines Deployment on Cloud Platform

    PubMed Central

    Dong, Yu-Shuang; Xu, Gao-Chao; Fu, Xiao-Dong

    2014-01-01

    The cloud platform provides various services to users. More and more cloud centers provide infrastructure as the main way of operating. To improve the utilization rate of the cloud center and to decrease the operating cost, the cloud center provides services according to requirements of users by sharding the resources with virtualization. Considering both QoS for users and cost saving for cloud computing providers, we try to maximize performance and minimize energy cost as well. In this paper, we propose a distributed parallel genetic algorithm (DPGA) of placement strategy for virtual machines deployment on cloud platform. It executes the genetic algorithm parallelly and distributedly on several selected physical hosts in the first stage. Then it continues to execute the genetic algorithm of the second stage with solutions obtained from the first stage as the initial population. The solution calculated by the genetic algorithm of the second stage is the optimal one of the proposed approach. The experimental results show that the proposed placement strategy of VM deployment can ensure QoS for users and it is more effective and more energy efficient than other placement strategies on the cloud platform. PMID:25097872

  3. A distributed parallel genetic algorithm of placement strategy for virtual machines deployment on cloud platform.

    PubMed

    Dong, Yu-Shuang; Xu, Gao-Chao; Fu, Xiao-Dong

    2014-01-01

    The cloud platform provides various services to users. More and more cloud centers provide infrastructure as the main way of operating. To improve the utilization rate of the cloud center and to decrease the operating cost, the cloud center provides services according to requirements of users by sharding the resources with virtualization. Considering both QoS for users and cost saving for cloud computing providers, we try to maximize performance and minimize energy cost as well. In this paper, we propose a distributed parallel genetic algorithm (DPGA) of placement strategy for virtual machines deployment on cloud platform. It executes the genetic algorithm parallelly and distributedly on several selected physical hosts in the first stage. Then it continues to execute the genetic algorithm of the second stage with solutions obtained from the first stage as the initial population. The solution calculated by the genetic algorithm of the second stage is the optimal one of the proposed approach. The experimental results show that the proposed placement strategy of VM deployment can ensure QoS for users and it is more effective and more energy efficient than other placement strategies on the cloud platform.

  4. An application of traveling salesman problem using the improved genetic algorithm on android google maps

    NASA Astrophysics Data System (ADS)

    Narwadi, Teguh; Subiyanto

    2017-03-01

    The Travelling Salesman Problem (TSP) is one of the best known NP-hard problems, which means that no exact algorithm to solve it in polynomial time. This paper present a new variant application genetic algorithm approach with a local search technique has been developed to solve the TSP. For the local search technique, an iterative hill climbing method has been used. The system is implemented on the Android OS because android is now widely used around the world and it is mobile system. It is also integrated with Google API that can to get the geographical location and the distance of the cities, and displays the route. Therefore, we do some experimentation to test the behavior of the application. To test the effectiveness of the application of hybrid genetic algorithm (HGA) is compare with the application of simple GA in 5 sample from the cities in Central Java, Indonesia with different numbers of cities. According to the experiment results obtained that in the average solution HGA shows in 5 tests out of 5 (100%) is better than simple GA. The results have shown that the hybrid genetic algorithm outperforms the genetic algorithm especially in the case with the problem higher complexity.

  5. A Guiding Evolutionary Algorithm with Greedy Strategy for Global Optimization Problems

    PubMed Central

    Cao, Leilei; Xu, Lihong; Goodman, Erik D.

    2016-01-01

    A Guiding Evolutionary Algorithm (GEA) with greedy strategy for global optimization problems is proposed. Inspired by Particle Swarm Optimization, the Genetic Algorithm, and the Bat Algorithm, the GEA was designed to retain some advantages of each method while avoiding some disadvantages. In contrast to the usual Genetic Algorithm, each individual in GEA is crossed with the current global best one instead of a randomly selected individual. The current best individual served as a guide to attract offspring to its region of genotype space. Mutation was added to offspring according to a dynamic mutation probability. To increase the capability of exploitation, a local search mechanism was applied to new individuals according to a dynamic probability of local search. Experimental results show that GEA outperformed the other three typical global optimization algorithms with which it was compared. PMID:27293421

  6. A Guiding Evolutionary Algorithm with Greedy Strategy for Global Optimization Problems.

    PubMed

    Cao, Leilei; Xu, Lihong; Goodman, Erik D

    2016-01-01

    A Guiding Evolutionary Algorithm (GEA) with greedy strategy for global optimization problems is proposed. Inspired by Particle Swarm Optimization, the Genetic Algorithm, and the Bat Algorithm, the GEA was designed to retain some advantages of each method while avoiding some disadvantages. In contrast to the usual Genetic Algorithm, each individual in GEA is crossed with the current global best one instead of a randomly selected individual. The current best individual served as a guide to attract offspring to its region of genotype space. Mutation was added to offspring according to a dynamic mutation probability. To increase the capability of exploitation, a local search mechanism was applied to new individuals according to a dynamic probability of local search. Experimental results show that GEA outperformed the other three typical global optimization algorithms with which it was compared.

  7. Modeling multilayer x-ray reflectivity using genetic algorithms

    NASA Astrophysics Data System (ADS)

    Sánchez del Río, M.; Pareschi, G.; Michetschläger, C.

    2000-06-01

    The x-ray reflectivity of a multilayer is a non-linear function of many parameters (materials, layer thickness, density, roughness). Non-linear fitting of experimental data with simulations requires the use of initial values sufficiently close to the optimum value. This is a difficult task when the topology of the space of the variables is highly structured. We apply global optimization methods to fit multilayer reflectivity. Genetic algorithms are stochastic methods based on the model of natural evolution: the improvement of a population along successive generations. A complete set of initial parameters constitutes an individual. The population is a collection of individuals. Each generation is built from the parent generation by applying some operators (selection, crossover, mutation, etc.) on the members of the parent generation. The pressure of selection drives the population to include "good" individuals. For large number of generations, the best individuals will approximate the optimum parameters. Some results on fitting experimental hard x-ray reflectivity data for Ni/C and W/Si multilayers using genetic algorithms are presented. This method can also be applied to design multilayers optimized for a target application.

  8. A High-Performance Genetic Algorithm: Using Traveling Salesman Problem as a Case

    PubMed Central

    Tsai, Chun-Wei; Tseng, Shih-Pang; Yang, Chu-Sing

    2014-01-01

    This paper presents a simple but efficient algorithm for reducing the computation time of genetic algorithm (GA) and its variants. The proposed algorithm is motivated by the observation that genes common to all the individuals of a GA have a high probability of surviving the evolution and ending up being part of the final solution; as such, they can be saved away to eliminate the redundant computations at the later generations of a GA. To evaluate the performance of the proposed algorithm, we use it not only to solve the traveling salesman problem but also to provide an extensive analysis on the impact it may have on the quality of the end result. Our experimental results indicate that the proposed algorithm can significantly reduce the computation time of GA and GA-based algorithms while limiting the degradation of the quality of the end result to a very small percentage compared to traditional GA. PMID:24892038

  9. A high-performance genetic algorithm: using traveling salesman problem as a case.

    PubMed

    Tsai, Chun-Wei; Tseng, Shih-Pang; Chiang, Ming-Chao; Yang, Chu-Sing; Hong, Tzung-Pei

    2014-01-01

    This paper presents a simple but efficient algorithm for reducing the computation time of genetic algorithm (GA) and its variants. The proposed algorithm is motivated by the observation that genes common to all the individuals of a GA have a high probability of surviving the evolution and ending up being part of the final solution; as such, they can be saved away to eliminate the redundant computations at the later generations of a GA. To evaluate the performance of the proposed algorithm, we use it not only to solve the traveling salesman problem but also to provide an extensive analysis on the impact it may have on the quality of the end result. Our experimental results indicate that the proposed algorithm can significantly reduce the computation time of GA and GA-based algorithms while limiting the degradation of the quality of the end result to a very small percentage compared to traditional GA.

  10. Genetic algorithms for the vehicle routing problem

    NASA Astrophysics Data System (ADS)

    Volna, Eva

    2016-06-01

    The Vehicle Routing Problem (VRP) is one of the most challenging combinatorial optimization tasks. This problem consists in designing the optimal set of routes for fleet of vehicles in order to serve a given set of customers. Evolutionary algorithms are general iterative algorithms for combinatorial optimization. These algorithms have been found to be very effective and robust in solving numerous problems from a wide range of application domains. This problem is known to be NP-hard; hence many heuristic procedures for its solution have been suggested. For such problems it is often desirable to obtain approximate solutions, so they can be found fast enough and are sufficiently accurate for the purpose. In this paper we have performed an experimental study that indicates the suitable use of genetic algorithms for the vehicle routing problem.

  11. 3D Protein structure prediction with genetic tabu search algorithm

    PubMed Central

    2010-01-01

    Background Protein structure prediction (PSP) has important applications in different fields, such as drug design, disease prediction, and so on. In protein structure prediction, there are two important issues. The first one is the design of the structure model and the second one is the design of the optimization technology. Because of the complexity of the realistic protein structure, the structure model adopted in this paper is a simplified model, which is called off-lattice AB model. After the structure model is assumed, optimization technology is needed for searching the best conformation of a protein sequence based on the assumed structure model. However, PSP is an NP-hard problem even if the simplest model is assumed. Thus, many algorithms have been developed to solve the global optimization problem. In this paper, a hybrid algorithm, which combines genetic algorithm (GA) and tabu search (TS) algorithm, is developed to complete this task. Results In order to develop an efficient optimization algorithm, several improved strategies are developed for the proposed genetic tabu search algorithm. The combined use of these strategies can improve the efficiency of the algorithm. In these strategies, tabu search introduced into the crossover and mutation operators can improve the local search capability, the adoption of variable population size strategy can maintain the diversity of the population, and the ranking selection strategy can improve the possibility of an individual with low energy value entering into next generation. Experiments are performed with Fibonacci sequences and real protein sequences. Experimental results show that the lowest energy obtained by the proposed GATS algorithm is lower than that obtained by previous methods. Conclusions The hybrid algorithm has the advantages from both genetic algorithm and tabu search algorithm. It makes use of the advantage of multiple search points in genetic algorithm, and can overcome poor hill-climbing capability in the conventional genetic algorithm by using the flexible memory functions of TS. Compared with some previous algorithms, GATS algorithm has better performance in global optimization and can predict 3D protein structure more effectively. PMID:20522256

  12. Distributed query plan generation using multiobjective genetic algorithm.

    PubMed

    Panicker, Shina; Kumar, T V Vijay

    2014-01-01

    A distributed query processing strategy, which is a key performance determinant in accessing distributed databases, aims to minimize the total query processing cost. One way to achieve this is by generating efficient distributed query plans that involve fewer sites for processing a query. In the case of distributed relational databases, the number of possible query plans increases exponentially with respect to the number of relations accessed by the query and the number of sites where these relations reside. Consequently, computing optimal distributed query plans becomes a complex problem. This distributed query plan generation (DQPG) problem has already been addressed using single objective genetic algorithm, where the objective is to minimize the total query processing cost comprising the local processing cost (LPC) and the site-to-site communication cost (CC). In this paper, this DQPG problem is formulated and solved as a biobjective optimization problem with the two objectives being minimize total LPC and minimize total CC. These objectives are simultaneously optimized using a multiobjective genetic algorithm NSGA-II. Experimental comparison of the proposed NSGA-II based DQPG algorithm with the single objective genetic algorithm shows that the former performs comparatively better and converges quickly towards optimal solutions for an observed crossover and mutation probability.

  13. Distributed Query Plan Generation Using Multiobjective Genetic Algorithm

    PubMed Central

    Panicker, Shina; Vijay Kumar, T. V.

    2014-01-01

    A distributed query processing strategy, which is a key performance determinant in accessing distributed databases, aims to minimize the total query processing cost. One way to achieve this is by generating efficient distributed query plans that involve fewer sites for processing a query. In the case of distributed relational databases, the number of possible query plans increases exponentially with respect to the number of relations accessed by the query and the number of sites where these relations reside. Consequently, computing optimal distributed query plans becomes a complex problem. This distributed query plan generation (DQPG) problem has already been addressed using single objective genetic algorithm, where the objective is to minimize the total query processing cost comprising the local processing cost (LPC) and the site-to-site communication cost (CC). In this paper, this DQPG problem is formulated and solved as a biobjective optimization problem with the two objectives being minimize total LPC and minimize total CC. These objectives are simultaneously optimized using a multiobjective genetic algorithm NSGA-II. Experimental comparison of the proposed NSGA-II based DQPG algorithm with the single objective genetic algorithm shows that the former performs comparatively better and converges quickly towards optimal solutions for an observed crossover and mutation probability. PMID:24963513

  14. Genetic algorithm enhanced by machine learning in dynamic aperture optimization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Yongjun; Cheng, Weixing; Yu, Li Hua

    With the aid of machine learning techniques, the genetic algorithm has been enhanced and applied to the multi-objective optimization problem presented by the dynamic aperture of the National Synchrotron Light Source II (NSLS-II) Storage Ring. During the evolution processes employed by the genetic algorithm, the population is classified into different clusters in the search space. The clusters with top average fitness are given “elite” status. Intervention on the population is implemented by repopulating some potentially competitive candidates based on the experience learned from the accumulated data. These candidates replace randomly selected candidates among the original data pool. The average fitnessmore » of the population is therefore improved while diversity is not lost. Maintaining diversity ensures that the optimization is global rather than local. The quality of the population increases and produces more competitive descendants accelerating the evolution process significantly. When identifying the distribution of optimal candidates, they appear to be located in isolated islands within the search space. Some of these optimal candidates have been experimentally confirmed at the NSLS-II storage ring. Furthermore, the machine learning techniques that exploit the genetic algorithm can also be used in other population-based optimization problems such as particle swarm algorithm.« less

  15. Genetic algorithm enhanced by machine learning in dynamic aperture optimization

    NASA Astrophysics Data System (ADS)

    Li, Yongjun; Cheng, Weixing; Yu, Li Hua; Rainer, Robert

    2018-05-01

    With the aid of machine learning techniques, the genetic algorithm has been enhanced and applied to the multi-objective optimization problem presented by the dynamic aperture of the National Synchrotron Light Source II (NSLS-II) Storage Ring. During the evolution processes employed by the genetic algorithm, the population is classified into different clusters in the search space. The clusters with top average fitness are given "elite" status. Intervention on the population is implemented by repopulating some potentially competitive candidates based on the experience learned from the accumulated data. These candidates replace randomly selected candidates among the original data pool. The average fitness of the population is therefore improved while diversity is not lost. Maintaining diversity ensures that the optimization is global rather than local. The quality of the population increases and produces more competitive descendants accelerating the evolution process significantly. When identifying the distribution of optimal candidates, they appear to be located in isolated islands within the search space. Some of these optimal candidates have been experimentally confirmed at the NSLS-II storage ring. The machine learning techniques that exploit the genetic algorithm can also be used in other population-based optimization problems such as particle swarm algorithm.

  16. Genetic algorithm enhanced by machine learning in dynamic aperture optimization

    DOE PAGES

    Li, Yongjun; Cheng, Weixing; Yu, Li Hua; ...

    2018-05-29

    With the aid of machine learning techniques, the genetic algorithm has been enhanced and applied to the multi-objective optimization problem presented by the dynamic aperture of the National Synchrotron Light Source II (NSLS-II) Storage Ring. During the evolution processes employed by the genetic algorithm, the population is classified into different clusters in the search space. The clusters with top average fitness are given “elite” status. Intervention on the population is implemented by repopulating some potentially competitive candidates based on the experience learned from the accumulated data. These candidates replace randomly selected candidates among the original data pool. The average fitnessmore » of the population is therefore improved while diversity is not lost. Maintaining diversity ensures that the optimization is global rather than local. The quality of the population increases and produces more competitive descendants accelerating the evolution process significantly. When identifying the distribution of optimal candidates, they appear to be located in isolated islands within the search space. Some of these optimal candidates have been experimentally confirmed at the NSLS-II storage ring. Furthermore, the machine learning techniques that exploit the genetic algorithm can also be used in other population-based optimization problems such as particle swarm algorithm.« less

  17. Quantitative analysis of terahertz spectra for illicit drugs using adaptive-range micro-genetic algorithm

    NASA Astrophysics Data System (ADS)

    Chen, Yi; Ma, Yong; Lu, Zheng; Peng, Bei; Chen, Qin

    2011-08-01

    In the field of anti-illicit drug applications, many suspicious mixture samples might consist of various drug components—for example, a mixture of methamphetamine, heroin, and amoxicillin—which makes spectral identification very difficult. A terahertz spectroscopic quantitative analysis method using an adaptive range micro-genetic algorithm with a variable internal population (ARVIPɛμGA) has been proposed. Five mixture cases are discussed using ARVIPɛμGA driven quantitative terahertz spectroscopic analysis in this paper. The devised simulation results show agreement with the previous experimental results, which suggested that the proposed technique has potential applications for terahertz spectral identifications of drug mixture components. The results show agreement with the results obtained using other experimental and numerical techniques.

  18. Discovery of a meta-stable Al-Sm phase with unknown stoichiometry using a genetic algorithm

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Feng; McBrearty, Ian; Ott, R. T.

    Unknown crystalline phases observed during the devitrification process of glassy metal alloys significantly limit our ability to understand and control phase selection in these systems driven far from equilibrium. Here, we report a new meta-stable Al 5Sm phase identified by simultaneously searching Al-rich compositions of the Al–Sm system, using an efficient genetic algorithm. The excellent match between calculated and experimental X-ray diffraction patterns confirms that this new phase appeared in the crystallization of melt-spun Al 90Sm 10 alloys.

  19. Retrieval of Dry Snow Parameters from Radiometric Data Using a Dense Medium Model and Genetic Algorithms

    NASA Technical Reports Server (NTRS)

    Tedesco, Marco; Kim, Edward J.

    2005-01-01

    In this paper, GA-based techniques are used to invert the equations of an electromagnetic model based on Dense Medium Radiative Transfer Theory (DMRT) under the Quasi Crystalline Approximation with Coherent Potential to retrieve snow depth, mean grain size and fractional volume from microwave brightness temperatures. The technique is initially tested on both noisy and not-noisy simulated data. During this phase, different configurations of genetic algorithm parameters are considered to quantify how their change can affect the algorithm performance. A configuration of GA parameters is then selected and the algorithm is applied to experimental data acquired during the NASA Cold Land Process Experiment. Snow parameters retrieved with the GA-DMRT technique are then compared with snow parameters measured on field.

  20. A Novel Algorithm Combining Finite State Method and Genetic Algorithm for Solving Crude Oil Scheduling Problem

    PubMed Central

    Duan, Qian-Qian; Yang, Gen-Ke; Pan, Chang-Chun

    2014-01-01

    A hybrid optimization algorithm combining finite state method (FSM) and genetic algorithm (GA) is proposed to solve the crude oil scheduling problem. The FSM and GA are combined to take the advantage of each method and compensate deficiencies of individual methods. In the proposed algorithm, the finite state method makes up for the weakness of GA which is poor at local searching ability. The heuristic returned by the FSM can guide the GA algorithm towards good solutions. The idea behind this is that we can generate promising substructure or partial solution by using FSM. Furthermore, the FSM can guarantee that the entire solution space is uniformly covered. Therefore, the combination of the two algorithms has better global performance than the existing GA or FSM which is operated individually. Finally, a real-life crude oil scheduling problem from the literature is used for conducting simulation. The experimental results validate that the proposed method outperforms the state-of-art GA method. PMID:24772031

  1. An efficient genetic algorithm for maximum coverage deployment in wireless sensor networks.

    PubMed

    Yoon, Yourim; Kim, Yong-Hyuk

    2013-10-01

    Sensor networks have a lot of applications such as battlefield surveillance, environmental monitoring, and industrial diagnostics. Coverage is one of the most important performance metrics for sensor networks since it reflects how well a sensor field is monitored. In this paper, we introduce the maximum coverage deployment problem in wireless sensor networks and analyze the properties of the problem and its solution space. Random deployment is the simplest way to deploy sensor nodes but may cause unbalanced deployment and therefore, we need a more intelligent way for sensor deployment. We found that the phenotype space of the problem is a quotient space of the genotype space in a mathematical view. Based on this property, we propose an efficient genetic algorithm using a novel normalization method. A Monte Carlo method is adopted to design an efficient evaluation function, and its computation time is decreased without loss of solution quality using a method that starts from a small number of random samples and gradually increases the number for subsequent generations. The proposed genetic algorithms could be further improved by combining with a well-designed local search. The performance of the proposed genetic algorithm is shown by a comparative experimental study. When compared with random deployment and existing methods, our genetic algorithm was not only about twice faster, but also showed significant performance improvement in quality.

  2. Experimental Design for Estimating Unknown Hydraulic Conductivity in a Confined Aquifer using a Genetic Algorithm and a Reduced Order Model

    NASA Astrophysics Data System (ADS)

    Ushijima, T.; Yeh, W.

    2013-12-01

    An optimal experimental design algorithm is developed to select locations for a network of observation wells that provides the maximum information about unknown hydraulic conductivity in a confined, anisotropic aquifer. The design employs a maximal information criterion that chooses, among competing designs, the design that maximizes the sum of squared sensitivities while conforming to specified design constraints. Because that the formulated problem is non-convex and contains integer variables (necessitating a combinatorial search), for a realistically-scaled model, the problem may be difficult, if not impossible, to solve through traditional mathematical programming techniques. Genetic Algorithms (GAs) are designed to search out the global optimum; however because a GA requires a large number of calls to a groundwater model, the formulated optimization problem may still be infeasible to solve. To overcome this, Proper Orthogonal Decomposition (POD) is applied to the groundwater model to reduce its dimension. The information matrix in the full model space can then be searched without solving the full model.

  3. An analysis of parameter sensitivities of preference-inspired co-evolutionary algorithms

    NASA Astrophysics Data System (ADS)

    Wang, Rui; Mansor, Maszatul M.; Purshouse, Robin C.; Fleming, Peter J.

    2015-10-01

    Many-objective optimisation problems remain challenging for many state-of-the-art multi-objective evolutionary algorithms. Preference-inspired co-evolutionary algorithms (PICEAs) which co-evolve the usual population of candidate solutions with a family of decision-maker preferences during the search have been demonstrated to be effective on such problems. However, it is unknown whether PICEAs are robust with respect to the parameter settings. This study aims to address this question. First, a global sensitivity analysis method - the Sobol' variance decomposition method - is employed to determine the relative importance of the parameters controlling the performance of PICEAs. Experimental results show that the performance of PICEAs is controlled for the most part by the number of function evaluations. Next, we investigate the effect of key parameters identified from the Sobol' test and the genetic operators employed in PICEAs. Experimental results show improved performance of the PICEAs as more preferences are co-evolved. Additionally, some suggestions for genetic operator settings are provided for non-expert users.

  4. Vertical decomposition with Genetic Algorithm for Multiple Sequence Alignment

    PubMed Central

    2011-01-01

    Background Many Bioinformatics studies begin with a multiple sequence alignment as the foundation for their research. This is because multiple sequence alignment can be a useful technique for studying molecular evolution and analyzing sequence structure relationships. Results In this paper, we have proposed a Vertical Decomposition with Genetic Algorithm (VDGA) for Multiple Sequence Alignment (MSA). In VDGA, we divide the sequences vertically into two or more subsequences, and then solve them individually using a guide tree approach. Finally, we combine all the subsequences to generate a new multiple sequence alignment. This technique is applied on the solutions of the initial generation and of each child generation within VDGA. We have used two mechanisms to generate an initial population in this research: the first mechanism is to generate guide trees with randomly selected sequences and the second is shuffling the sequences inside such trees. Two different genetic operators have been implemented with VDGA. To test the performance of our algorithm, we have compared it with existing well-known methods, namely PRRP, CLUSTALX, DIALIGN, HMMT, SB_PIMA, ML_PIMA, MULTALIGN, and PILEUP8, and also other methods, based on Genetic Algorithms (GA), such as SAGA, MSA-GA and RBT-GA, by solving a number of benchmark datasets from BAliBase 2.0. Conclusions The experimental results showed that the VDGA with three vertical divisions was the most successful variant for most of the test cases in comparison to other divisions considered with VDGA. The experimental results also confirmed that VDGA outperformed the other methods considered in this research. PMID:21867510

  5. Demonstrating the suitability of genetic algorithms for driving microbial ecosystems in desirable directions.

    PubMed

    Vandecasteele, Frederik P J; Hess, Thomas F; Crawford, Ronald L

    2007-07-01

    The functioning of natural microbial ecosystems is determined by biotic interactions, which are in turn influenced by abiotic environmental conditions. Direct experimental manipulation of such conditions can be used to purposefully drive ecosystems toward exhibiting desirable functions. When a set of environmental conditions can be manipulated to be present at a discrete number of levels, finding the right combination of conditions to obtain the optimal desired effect becomes a typical combinatorial optimisation problem. Genetic algorithms are a class of robust and flexible search and optimisation techniques from the field of computer science that may be very suitable for such a task. To verify this idea, datasets containing growth levels of the total microbial community of four different natural microbial ecosystems in response to all possible combinations of a set of five chemical supplements were obtained. Subsequently, the ability of a genetic algorithm to search this parameter space for combinations of supplements driving the microbial communities to high levels of growth was compared to that of a random search, a local search, and a hill-climbing algorithm, three intuitive alternative optimisation approaches. The results indicate that a genetic algorithm is very suitable for driving microbial ecosystems in desirable directions, which opens opportunities for both fundamental ecological research and industrial applications.

  6. Analytical optimal pulse shapes obtained with the aid of genetic algorithms

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Guerrero, Rubén D., E-mail: rdguerrerom@unal.edu.co; Arango, Carlos A.; Reyes, Andrés

    2015-09-28

    We propose a methodology to design optimal pulses for achieving quantum optimal control on molecular systems. Our approach constrains pulse shapes to linear combinations of a fixed number of experimentally relevant pulse functions. Quantum optimal control is obtained by maximizing a multi-target fitness function using genetic algorithms. As a first application of the methodology, we generated an optimal pulse that successfully maximized the yield on a selected dissociation channel of a diatomic molecule. Our pulse is obtained as a linear combination of linearly chirped pulse functions. Data recorded along the evolution of the genetic algorithm contained important information regarding themore » interplay between radiative and diabatic processes. We performed a principal component analysis on these data to retrieve the most relevant processes along the optimal path. Our proposed methodology could be useful for performing quantum optimal control on more complex systems by employing a wider variety of pulse shape functions.« less

  7. Beam-column joint shear prediction using hybridized deep learning neural network with genetic algorithm

    NASA Astrophysics Data System (ADS)

    Mundher Yaseen, Zaher; Abdulmohsin Afan, Haitham; Tran, Minh-Tung

    2018-04-01

    Scientifically evidenced that beam-column joints are a critical point in the reinforced concrete (RC) structure under the fluctuation loads effects. In this novel hybrid data-intelligence model developed to predict the joint shear behavior of exterior beam-column structure frame. The hybrid data-intelligence model is called genetic algorithm integrated with deep learning neural network model (GA-DLNN). The genetic algorithm is used as prior modelling phase for the input approximation whereas the DLNN predictive model is used for the prediction phase. To demonstrate this structural problem, experimental data is collected from the literature that defined the dimensional and specimens’ properties. The attained findings evidenced the efficitveness of the hybrid GA-DLNN in modelling beam-column joint shear problem. In addition, the accurate prediction achived with less input variables owing to the feasibility of the evolutionary phase.

  8. Optimization of culture conditions and bench-scale production of L-asparaginase by submerged fermentation of Aspergillus terreus MTCC 1782.

    PubMed

    Gurunathan, Baskar; Sahadevan, Renganathan

    2012-07-01

    Optimization of culture conditions for L-asparaginase production by submerged fermentation of Aspergillus terreus MTCC 1782 was studied using a 3-level central composite design of response surface methodology and artificial neural network linked genetic algorithm. The artificial neural network linked genetic algorithm was found to be more efficient than response surface methodology. The experimental L-asparaginase activity of 43.29 IU/ml was obtained at the optimum culture conditions of temperature 35 degrees C, initial pH 6.3, inoculum size 1% (v/v), agitation rate 140 rpm, and incubation time 58.5 h of the artificial neural network linked genetic algorithm, which was close to the predicted activity of 44.38 IU/ml. Characteristics of L-asparaginase production by A. terreus MTCC 1782 were studied in a 3 L bench-scale bioreactor.

  9. Fashion sketch design by interactive genetic algorithms

    NASA Astrophysics Data System (ADS)

    Mok, P. Y.; Wang, X. X.; Xu, J.; Kwok, Y. L.

    2012-11-01

    Computer aided design is vitally important for the modern industry, particularly for the creative industry. Fashion industry faced intensive challenges to shorten the product development process. In this paper, a methodology is proposed for sketch design based on interactive genetic algorithms. The sketch design system consists of a sketch design model, a database and a multi-stage sketch design engine. First, a sketch design model is developed based on the knowledge of fashion design to describe fashion product characteristics by using parameters. Second, a database is built based on the proposed sketch design model to define general style elements. Third, a multi-stage sketch design engine is used to construct the design. Moreover, an interactive genetic algorithm (IGA) is used to accelerate the sketch design process. The experimental results have demonstrated that the proposed method is effective in helping laypersons achieve satisfied fashion design sketches.

  10. A comparative study of electrochemical machining process parameters by using GA and Taguchi method

    NASA Astrophysics Data System (ADS)

    Soni, S. K.; Thomas, B.

    2017-11-01

    In electrochemical machining quality of machined surface strongly depend on the selection of optimal parameter settings. This work deals with the application of Taguchi method and genetic algorithm using MATLAB to maximize the metal removal rate and minimize the surface roughness and overcut. In this paper a comparative study is presented for drilling of LM6 AL/B4C composites by comparing the significant impact of numerous machining process parameters such as, electrolyte concentration (g/l),machining voltage (v),frequency (hz) on the response parameters (surface roughness, material removal rate and over cut). Taguchi L27 orthogonal array was chosen in Minitab 17 software, for the investigation of experimental results and also multiobjective optimization done by genetic algorithm is employed by using MATLAB. After obtaining optimized results from Taguchi method and genetic algorithm, a comparative results are presented.

  11. Test Scheduling for Core-Based SOCs Using Genetic Algorithm Based Heuristic Approach

    NASA Astrophysics Data System (ADS)

    Giri, Chandan; Sarkar, Soumojit; Chattopadhyay, Santanu

    This paper presents a Genetic algorithm (GA) based solution to co-optimize test scheduling and wrapper design for core based SOCs. Core testing solutions are generated as a set of wrapper configurations, represented as rectangles with width equal to the number of TAM (Test Access Mechanism) channels and height equal to the corresponding testing time. A locally optimal best-fit heuristic based bin packing algorithm has been used to determine placement of rectangles minimizing the overall test times, whereas, GA has been utilized to generate the sequence of rectangles to be considered for placement. Experimental result on ITC'02 benchmark SOCs shows that the proposed method provides better solutions compared to the recent works reported in the literature.

  12. Discovery of a meta-stable Al–Sm phase with unknown stoichiometry using a genetic algorithm

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Feng; McBrearty, Ian; Ott, R T

    Unknown crystalline phases observed during the devitrification process of glassy metal alloys significantly limit our ability to understand and control phase selection in these systems driven far from equilibrium. Here, we report a new meta-stable Al5Sm phase identified by simultaneously searching Al-rich compositions of the Al-Sm system, using an efficient genetic algorithm. The excellent match between calculated and experimental X-ray diffraction patterns confirms that this new phase appeared in the crystallization of melt-spun Al90Sm10 alloys. Published by Elsevier Ltd. on behalf of Acta Materialia Inc.

  13. Random search optimization based on genetic algorithm and discriminant function

    NASA Technical Reports Server (NTRS)

    Kiciman, M. O.; Akgul, M.; Erarslanoglu, G.

    1990-01-01

    The general problem of optimization with arbitrary merit and constraint functions, which could be convex, concave, monotonic, or non-monotonic, is treated using stochastic methods. To improve the efficiency of the random search methods, a genetic algorithm for the search phase and a discriminant function for the constraint-control phase were utilized. The validity of the technique is demonstrated by comparing the results to published test problem results. Numerical experimentation indicated that for cases where a quick near optimum solution is desired, a general, user-friendly optimization code can be developed without serious penalties in both total computer time and accuracy.

  14. Improved Adaptive LSB Steganography Based on Chaos and Genetic Algorithm

    NASA Astrophysics Data System (ADS)

    Yu, Lifang; Zhao, Yao; Ni, Rongrong; Li, Ting

    2010-12-01

    We propose a novel steganographic method in JPEG images with high performance. Firstly, we propose improved adaptive LSB steganography, which can achieve high capacity while preserving the first-order statistics. Secondly, in order to minimize visual degradation of the stego image, we shuffle bits-order of the message based on chaos whose parameters are selected by the genetic algorithm. Shuffling message's bits-order provides us with a new way to improve the performance of steganography. Experimental results show that our method outperforms classical steganographic methods in image quality, while preserving characteristics of histogram and providing high capacity.

  15. Genetically Engineered Microelectronic Infrared Filters

    NASA Technical Reports Server (NTRS)

    Cwik, Tom; Klimeck, Gerhard

    1998-01-01

    A genetic algorithm is used for design of infrared filters and in the understanding of the material structure of a resonant tunneling diode. These two components are examples of microdevices and nanodevices that can be numerically simulated using fundamental mathematical and physical models. Because the number of parameters that can be used in the design of one of these devices is large, and because experimental exploration of the design space is unfeasible, reliable software models integrated with global optimization methods are examined The genetic algorithm and engineering design codes have been implemented on massively parallel computers to exploit their high performance. Design results are presented for the infrared filter showing new and optimized device design. Results for nanodevices are presented in a companion paper at this workshop.

  16. Physics-Based Image Segmentation Using First Order Statistical Properties and Genetic Algorithm for Inductive Thermography Imaging.

    PubMed

    Gao, Bin; Li, Xiaoqing; Woo, Wai Lok; Tian, Gui Yun

    2018-05-01

    Thermographic inspection has been widely applied to non-destructive testing and evaluation with the capabilities of rapid, contactless, and large surface area detection. Image segmentation is considered essential for identifying and sizing defects. To attain a high-level performance, specific physics-based models that describe defects generation and enable the precise extraction of target region are of crucial importance. In this paper, an effective genetic first-order statistical image segmentation algorithm is proposed for quantitative crack detection. The proposed method automatically extracts valuable spatial-temporal patterns from unsupervised feature extraction algorithm and avoids a range of issues associated with human intervention in laborious manual selection of specific thermal video frames for processing. An internal genetic functionality is built into the proposed algorithm to automatically control the segmentation threshold to render enhanced accuracy in sizing the cracks. Eddy current pulsed thermography will be implemented as a platform to demonstrate surface crack detection. Experimental tests and comparisons have been conducted to verify the efficacy of the proposed method. In addition, a global quantitative assessment index F-score has been adopted to objectively evaluate the performance of different segmentation algorithms.

  17. Data mining for multiagent rules, strategies, and fuzzy decision tree structure

    NASA Astrophysics Data System (ADS)

    Smith, James F., III; Rhyne, Robert D., II; Fisher, Kristin

    2002-03-01

    A fuzzy logic based resource manager (RM) has been developed that automatically allocates electronic attack resources in real-time over many dissimilar platforms. Two different data mining algorithms have been developed to determine rules, strategies, and fuzzy decision tree structure. The first data mining algorithm uses a genetic algorithm as a data mining function and is called from an electronic game. The game allows a human expert to play against the resource manager in a simulated battlespace with each of the defending platforms being exclusively directed by the fuzzy resource manager and the attacking platforms being controlled by the human expert or operating autonomously under their own logic. This approach automates the data mining problem. The game automatically creates a database reflecting the domain expert's knowledge. It calls a data mining function, a genetic algorithm, for data mining of the database as required and allows easy evaluation of the information mined in the second step. The criterion for re- optimization is discussed as well as experimental results. Then a second data mining algorithm that uses a genetic program as a data mining function is introduced to automatically discover fuzzy decision tree structures. Finally, a fuzzy decision tree generated through this process is discussed.

  18. High performance genetic algorithm for VLSI circuit partitioning

    NASA Astrophysics Data System (ADS)

    Dinu, Simona

    2016-12-01

    Partitioning is one of the biggest challenges in computer-aided design for VLSI circuits (very large-scale integrated circuits). This work address the min-cut balanced circuit partitioning problem- dividing the graph that models the circuit into almost equal sized k sub-graphs while minimizing the number of edges cut i.e. minimizing the number of edges connecting the sub-graphs. The problem may be formulated as a combinatorial optimization problem. Experimental studies in the literature have shown the problem to be NP-hard and thus it is important to design an efficient heuristic algorithm to solve it. The approach proposed in this study is a parallel implementation of a genetic algorithm, namely an island model. The information exchange between the evolving subpopulations is modeled using a fuzzy controller, which determines an optimal balance between exploration and exploitation of the solution space. The results of simulations show that the proposed algorithm outperforms the standard sequential genetic algorithm both in terms of solution quality and convergence speed. As a direction for future study, this research can be further extended to incorporate local search operators which should include problem-specific knowledge. In addition, the adaptive configuration of mutation and crossover rates is another guidance for future research.

  19. A genetic graph-based approach for partitional clustering.

    PubMed

    Menéndez, Héctor D; Barrero, David F; Camacho, David

    2014-05-01

    Clustering is one of the most versatile tools for data analysis. In the recent years, clustering that seeks the continuity of data (in opposition to classical centroid-based approaches) has attracted an increasing research interest. It is a challenging problem with a remarkable practical interest. The most popular continuity clustering method is the spectral clustering (SC) algorithm, which is based on graph cut: It initially generates a similarity graph using a distance measure and then studies its graph spectrum to find the best cut. This approach is sensitive to the parameters of the metric, and a correct parameter choice is critical to the quality of the cluster. This work proposes a new algorithm, inspired by SC, that reduces the parameter dependency while maintaining the quality of the solution. The new algorithm, named genetic graph-based clustering (GGC), takes an evolutionary approach introducing a genetic algorithm (GA) to cluster the similarity graph. The experimental validation shows that GGC increases robustness of SC and has competitive performance in comparison with classical clustering methods, at least, in the synthetic and real dataset used in the experiments.

  20. Evolutionary computation applied to the reconstruction of 3-D surface topography in the SEM.

    PubMed

    Kodama, Tetsuji; Li, Xiaoyuan; Nakahira, Kenji; Ito, Dai

    2005-10-01

    A genetic algorithm has been applied to the line profile reconstruction from the signals of the standard secondary electron (SE) and/or backscattered electron detectors in a scanning electron microscope. This method solves the topographical surface reconstruction problem as one of combinatorial optimization. To extend this optimization approach for three-dimensional (3-D) surface topography, this paper considers the use of a string coding where a 3-D surface topography is represented by a set of coordinates of vertices. We introduce the Delaunay triangulation, which attains the minimum roughness for any set of height data to capture the fundamental features of the surface being probed by an electron beam. With this coding, the strings are processed with a class of hybrid optimization algorithms that combine genetic algorithms and simulated annealing algorithms. Experimental results on SE images are presented.

  1. Genetic algorithm based active vibration control for a moving flexible smart beam driven by a pneumatic rod cylinder

    NASA Astrophysics Data System (ADS)

    Qiu, Zhi-cheng; Shi, Ming-li; Wang, Bin; Xie, Zhuo-wei

    2012-05-01

    A rod cylinder based pneumatic driving scheme is proposed to suppress the vibration of a flexible smart beam. Pulse code modulation (PCM) method is employed to control the motion of the cylinder's piston rod for simultaneous positioning and vibration suppression. Firstly, the system dynamics model is derived using Hamilton principle. Its standard state-space representation is obtained for characteristic analysis, controller design, and simulation. Secondly, a genetic algorithm (GA) is applied to optimize and tune the control gain parameters adaptively based on the specific performance index. Numerical simulations are performed on the pneumatic driving elastic beam system, using the established model and controller with tuned gains by GA optimization process. Finally, an experimental setup for the flexible beam driven by a pneumatic rod cylinder is constructed. Experiments for suppressing vibrations of the flexible beam are conducted. Theoretical analysis, numerical simulation and experimental results demonstrate that the proposed pneumatic drive scheme and the adopted control algorithms are feasible. The large amplitude vibration of the first bending mode can be suppressed effectively.

  2. Accelerated optimization and automated discovery with covariance matrix adaptation for experimental quantum control

    NASA Astrophysics Data System (ADS)

    Roslund, Jonathan; Shir, Ofer M.; Bäck, Thomas; Rabitz, Herschel

    2009-10-01

    Optimization of quantum systems by closed-loop adaptive pulse shaping offers a rich domain for the development and application of specialized evolutionary algorithms. Derandomized evolution strategies (DESs) are presented here as a robust class of optimizers for experimental quantum control. The combination of stochastic and quasi-local search embodied by these algorithms is especially amenable to the inherent topology of quantum control landscapes. Implementation of DES in the laboratory results in efficiency gains of up to ˜9 times that of the standard genetic algorithm, and thus is a promising tool for optimization of unstable or fragile systems. The statistical learning upon which these algorithms are predicated also provide the means for obtaining a control problem’s Hessian matrix with no additional experimental overhead. The forced optimal covariance adaptive learning (FOCAL) method is introduced to enable retrieval of the Hessian matrix, which can reveal information about the landscape’s local structure and dynamic mechanism. Exploitation of such algorithms in quantum control experiments should enhance their efficiency and provide additional fundamental insights.

  3. Design of artificial neural networks using a genetic algorithm to predict collection efficiency in venturi scrubbers.

    PubMed

    Taheri, Mahboobeh; Mohebbi, Ali

    2008-08-30

    In this study, a new approach for the auto-design of neural networks, based on a genetic algorithm (GA), has been used to predict collection efficiency in venturi scrubbers. The experimental input data, including particle diameter, throat gas velocity, liquid to gas flow rate ratio, throat hydraulic diameter, pressure drop across the venturi scrubber and collection efficiency as an output, have been used to create a GA-artificial neural network (ANN) model. The testing results from the model are in good agreement with the experimental data. Comparison of the results of the GA optimized ANN model with the results from the trial-and-error calibrated ANN model indicates that the GA-ANN model is more efficient. Finally, the effects of operating parameters such as liquid to gas flow rate ratio, throat gas velocity, and particle diameter on collection efficiency were determined.

  4. Modeling and optimization of joint quality for laser transmission joint of thermoplastic using an artificial neural network and a genetic algorithm

    NASA Astrophysics Data System (ADS)

    Wang, Xiao; Zhang, Cheng; Li, Pin; Wang, Kai; Hu, Yang; Zhang, Peng; Liu, Huixia

    2012-11-01

    A central composite rotatable experimental design(CCRD) is conducted to design experiments for laser transmission joining of thermoplastic-Polycarbonate (PC). The artificial neural network was used to establish the relationships between laser transmission joining process parameters (the laser power, velocity, clamp pressure, scanning number) and joint strength and joint seam width. The developed mathematical models are tested by analysis of variance (ANOVA) method to check their adequacy and the effects of process parameters on the responses and the interaction effects of key process parameters on the quality are analyzed and discussed. Finally, the desirability function coupled with genetic algorithm is used to carry out the optimization of the joint strength and joint width. The results show that the predicted results of the optimization are in good agreement with the experimental results, so this study provides an effective method to enhance the joint quality.

  5. Optimization to the Culture Conditions for Phellinus Production with Regression Analysis and Gene-Set Based Genetic Algorithm

    PubMed Central

    Li, Zhongwei; Xin, Yuezhen; Wang, Xun; Sun, Beibei; Xia, Shengyu; Li, Hui

    2016-01-01

    Phellinus is a kind of fungus and is known as one of the elemental components in drugs to avoid cancers. With the purpose of finding optimized culture conditions for Phellinus production in the laboratory, plenty of experiments focusing on single factor were operated and large scale of experimental data were generated. In this work, we use the data collected from experiments for regression analysis, and then a mathematical model of predicting Phellinus production is achieved. Subsequently, a gene-set based genetic algorithm is developed to optimize the values of parameters involved in culture conditions, including inoculum size, PH value, initial liquid volume, temperature, seed age, fermentation time, and rotation speed. These optimized values of the parameters have accordance with biological experimental results, which indicate that our method has a good predictability for culture conditions optimization. PMID:27610365

  6. A Selfish Constraint Satisfaction Genetic Algorithms for Planning a Long-Distance Transportation Network

    NASA Astrophysics Data System (ADS)

    Onoyama, Takashi; Maekawa, Takuya; Kubota, Sen; Tsuruta, Setuso; Komoda, Norihisa

    To build a cooperative logistics network covering multiple enterprises, a planning method that can build a long-distance transportation network is required. Many strict constraints are imposed on this type of problem. To solve these strict-constraint problems, a selfish constraint satisfaction genetic algorithm (GA) is proposed. In this GA, each gene of an individual satisfies only its constraint selfishly, disregarding the constraints of other genes in the same individuals. Moreover, a constraint pre-checking method is also applied to improve the GA convergence speed. The experimental result shows the proposed method can obtain an accurate solution in a practical response time.

  7. Identification of handwriting by using the genetic algorithm (GA) and support vector machine (SVM)

    NASA Astrophysics Data System (ADS)

    Zhang, Qigui; Deng, Kai

    2016-12-01

    As portable digital camera and a camera phone comes more and more popular, and equally pressing is meeting the requirements of people to shoot at any time, to identify and storage handwritten character. In this paper, genetic algorithm(GA) and support vector machine(SVM)are used for identification of handwriting. Compare with parameters-optimized method, this technique overcomes two defects: first, it's easy to trap in the local optimum; second, finding the best parameters in the larger range will affects the efficiency of classification and prediction. As the experimental results suggest, GA-SVM has a higher recognition rate.

  8. Modeling Self-Healing of Concrete Using Hybrid Genetic Algorithm-Artificial Neural Network.

    PubMed

    Ramadan Suleiman, Ahmed; Nehdi, Moncef L

    2017-02-07

    This paper presents an approach to predicting the intrinsic self-healing in concrete using a hybrid genetic algorithm-artificial neural network (GA-ANN). A genetic algorithm was implemented in the network as a stochastic optimizing tool for the initial optimal weights and biases. This approach can assist the network in achieving a global optimum and avoid the possibility of the network getting trapped at local optima. The proposed model was trained and validated using an especially built database using various experimental studies retrieved from the open literature. The model inputs include the cement content, water-to-cement ratio (w/c), type and dosage of supplementary cementitious materials, bio-healing materials, and both expansive and crystalline additives. Self-healing indicated by means of crack width is the model output. The results showed that the proposed GA-ANN model is capable of capturing the complex effects of various self-healing agents (e.g., biochemical material, silica-based additive, expansive and crystalline components) on the self-healing performance in cement-based materials.

  9. A novel hybrid genetic algorithm to solve the make-to-order sequence-dependent flow-shop scheduling problem

    NASA Astrophysics Data System (ADS)

    Mirabi, Mohammad; Fatemi Ghomi, S. M. T.; Jolai, F.

    2014-04-01

    Flow-shop scheduling problem (FSP) deals with the scheduling of a set of n jobs that visit a set of m machines in the same order. As the FSP is NP-hard, there is no efficient algorithm to reach the optimal solution of the problem. To minimize the holding, delay and setup costs of large permutation flow-shop scheduling problems with sequence-dependent setup times on each machine, this paper develops a novel hybrid genetic algorithm (HGA) with three genetic operators. Proposed HGA applies a modified approach to generate a pool of initial solutions, and also uses an improved heuristic called the iterated swap procedure to improve the initial solutions. We consider the make-to-order production approach that some sequences between jobs are assumed as tabu based on maximum allowable setup cost. In addition, the results are compared to some recently developed heuristics and computational experimental results show that the proposed HGA performs very competitively with respect to accuracy and efficiency of solution.

  10. Enhancing the performance of MOEAs: an experimental presentation of a new fitness guided mutation operator

    NASA Astrophysics Data System (ADS)

    Liagkouras, K.; Metaxiotis, K.

    2017-01-01

    Multi-objective evolutionary algorithms (MOEAs) are currently a dynamic field of research that has attracted considerable attention. Mutation operators have been utilized by MOEAs as variation mechanisms. In particular, polynomial mutation (PLM) is one of the most popular variation mechanisms and has been utilized by many well-known MOEAs. In this paper, we revisit the PLM operator and we propose a fitness-guided version of the PLM. Experimental results obtained by non-dominated sorting genetic algorithm II and strength Pareto evolutionary algorithm 2 show that the proposed fitness-guided mutation operator outperforms the classical PLM operator, based on different performance metrics that evaluate both the proximity of the solutions to the Pareto front and their dispersion on it.

  11. Pulse retrieval algorithm for interferometric frequency-resolved optical gating based on differential evolution.

    PubMed

    Hyyti, Janne; Escoto, Esmerando; Steinmeyer, Günter

    2017-10-01

    A novel algorithm for the ultrashort laser pulse characterization method of interferometric frequency-resolved optical gating (iFROG) is presented. Based on a genetic method, namely, differential evolution, the algorithm can exploit all available information of an iFROG measurement to retrieve the complex electric field of a pulse. The retrieval is subjected to a series of numerical tests to prove the robustness of the algorithm against experimental artifacts and noise. These tests show that the integrated error-correction mechanisms of the iFROG method can be successfully used to remove the effect from timing errors and spectrally varying efficiency in the detection. Moreover, the accuracy and noise resilience of the new algorithm are shown to outperform retrieval based on the generalized projections algorithm, which is widely used as the standard method in FROG retrieval. The differential evolution algorithm is further validated with experimental data, measured with unamplified three-cycle pulses from a mode-locked Ti:sapphire laser. Additionally introducing group delay dispersion in the beam path, the retrieval results show excellent agreement with independent measurements with a commercial pulse measurement device based on spectral phase interferometry for direct electric-field retrieval. Further experimental tests with strongly attenuated pulses indicate resilience of differential-evolution-based retrieval against massive measurement noise.

  12. Optimizing an experimental design for an electromagnetic experiment

    NASA Astrophysics Data System (ADS)

    Roux, Estelle; Garcia, Xavier

    2013-04-01

    Most of geophysical studies focus on data acquisition and analysis, but another aspect which is gaining importance is the discussion on acquisition of suitable datasets. This can be done through the design of an optimal experiment. Optimizing an experimental design implies a compromise between maximizing the information we get about the target and reducing the cost of the experiment, considering a wide range of constraints (logistical, financial, experimental …). We are currently developing a method to design an optimal controlled-source electromagnetic (CSEM) experiment to detect a potential CO2 reservoir and monitor this reservoir during and after CO2 injection. Our statistical algorithm combines the use of linearized inverse theory (to evaluate the quality of one given design via the objective function) and stochastic optimization methods like genetic algorithm (to examine a wide range of possible surveys). The particularity of our method is that it uses a multi-objective genetic algorithm that searches for designs that fit several objective functions simultaneously. One main advantage of this kind of technique to design an experiment is that it does not require the acquisition of any data and can thus be easily conducted before any geophysical survey. Our new experimental design algorithm has been tested with a realistic one-dimensional resistivity model of the Earth in the region of study (northern Spain CO2 sequestration test site). We show that a small number of well distributed observations have the potential to resolve the target. This simple test also points out the importance of a well chosen objective function. Finally, in the context of CO2 sequestration that motivates this study, we might be interested in maximizing the information we get about the reservoir layer. In that case, we show how the combination of two different objective functions considerably improve its resolution.

  13. Estimation of the Reactive Flow Model Parameters for an Ammonium Nitrate-Based Emulsion Explosive Using Genetic Algorithms

    NASA Astrophysics Data System (ADS)

    Ribeiro, J. B.; Silva, C.; Mendes, R.

    2010-10-01

    A real coded genetic algorithm methodology that has been developed for the estimation of the parameters of the reaction rate equation of the Lee-Tarver reactive flow model is described in detail. This methodology allows, in a single optimization procedure, using only one experimental result and, without the need of any starting solution, to seek the 15 parameters of the reaction rate equation that fit the numerical to the experimental results. Mass averaging and the plate-gap model have been used for the determination of the shock data used in the unreacted explosive JWL equation of state (EOS) assessment and the thermochemical code THOR retrieved the data used in the detonation products' JWL EOS assessments. The developed methodology was applied for the estimation of the referred parameters for an ammonium nitrate-based emulsion explosive using poly(methyl methacrylate) (PMMA)-embedded manganin gauge pressure-time data. The obtained parameters allow a reasonably good description of the experimental data and show some peculiarities arising from the intrinsic nature of this kind of composite explosive.

  14. SS-mPMG and SS-GA: tools for finding pathways and dynamic simulation of metabolic networks.

    PubMed

    Katsuragi, Tetsuo; Ono, Naoaki; Yasumoto, Keiichi; Altaf-Ul-Amin, Md; Hirai, Masami Y; Sriyudthsak, Kansuporn; Sawada, Yuji; Yamashita, Yui; Chiba, Yukako; Onouchi, Hitoshi; Fujiwara, Toru; Naito, Satoshi; Shiraishi, Fumihide; Kanaya, Shigehiko

    2013-05-01

    Metabolomics analysis tools can provide quantitative information on the concentration of metabolites in an organism. In this paper, we propose the minimum pathway model generator tool for simulating the dynamics of metabolite concentrations (SS-mPMG) and a tool for parameter estimation by genetic algorithm (SS-GA). SS-mPMG can extract a subsystem of the metabolic network from the genome-scale pathway maps to reduce the complexity of the simulation model and automatically construct a dynamic simulator to evaluate the experimentally observed behavior of metabolites. Using this tool, we show that stochastic simulation can reproduce experimentally observed dynamics of amino acid biosynthesis in Arabidopsis thaliana. In this simulation, SS-mPMG extracts the metabolic network subsystem from published databases. The parameters needed for the simulation are determined using a genetic algorithm to fit the simulation results to the experimental data. We expect that SS-mPMG and SS-GA will help researchers to create relevant metabolic networks and carry out simulations of metabolic reactions derived from metabolomics data.

  15. Active Solution Space and Search on Job-shop Scheduling Problem

    NASA Astrophysics Data System (ADS)

    Watanabe, Masato; Ida, Kenichi; Gen, Mitsuo

    In this paper we propose a new searching method of Genetic Algorithm for Job-shop scheduling problem (JSP). The coding method that represent job number in order to decide a priority to arrange a job to Gannt Chart (called the ordinal representation with a priority) in JSP, an active schedule is created by using left shift. We define an active solution at first. It is solution which can create an active schedule without using left shift, and set of its defined an active solution space. Next, we propose an algorithm named Genetic Algorithm with active solution space search (GA-asol) which can create an active solution while solution is evaluated, in order to search the active solution space effectively. We applied it for some benchmark problems to compare with other method. The experimental results show good performance.

  16. Scope of Gradient and Genetic Algorithms in Multivariable Function Optimization

    NASA Technical Reports Server (NTRS)

    Shaykhian, Gholam Ali; Sen, S. K.

    2007-01-01

    Global optimization of a multivariable function - constrained by bounds specified on each variable and also unconstrained - is an important problem with several real world applications. Deterministic methods such as the gradient algorithms as well as the randomized methods such as the genetic algorithms may be employed to solve these problems. In fact, there are optimization problems where a genetic algorithm/an evolutionary approach is preferable at least from the quality (accuracy) of the results point of view. From cost (complexity) point of view, both gradient and genetic approaches are usually polynomial-time; there are no serious differences in this regard, i.e., the computational complexity point of view. However, for certain types of problems, such as those with unacceptably erroneous numerical partial derivatives and those with physically amplified analytical partial derivatives whose numerical evaluation involves undesirable errors and/or is messy, a genetic (stochastic) approach should be a better choice. We have presented here the pros and cons of both the approaches so that the concerned reader/user can decide which approach is most suited for the problem at hand. Also for the function which is known in a tabular form, instead of an analytical form, as is often the case in an experimental environment, we attempt to provide an insight into the approaches focusing our attention toward accuracy. Such an insight will help one to decide which method, out of several available methods, should be employed to obtain the best (least error) output. *

  17. Flight plan optimization

    NASA Astrophysics Data System (ADS)

    Dharmaseelan, Anoop; Adistambha, Keyne D.

    2015-05-01

    Fuel cost accounts for 40 percent of the operating cost of an airline. Fuel cost can be minimized by planning a flight on optimized routes. The routes can be optimized by searching best connections based on the cost function defined by the airline. The most common algorithm that used to optimize route search is Dijkstra's. Dijkstra's algorithm produces a static result and the time taken for the search is relatively long. This paper experiments a new algorithm to optimize route search which combines the principle of simulated annealing and genetic algorithm. The experimental results of route search, presented are shown to be computationally fast and accurate compared with timings from generic algorithm. The new algorithm is optimal for random routing feature that is highly sought by many regional operators.

  18. Exploiting Genomic Knowledge in Optimising Molecular Breeding Programmes: Algorithms from Evolutionary Computing

    PubMed Central

    O'Hagan, Steve; Knowles, Joshua; Kell, Douglas B.

    2012-01-01

    Comparatively few studies have addressed directly the question of quantifying the benefits to be had from using molecular genetic markers in experimental breeding programmes (e.g. for improved crops and livestock), nor the question of which organisms should be mated with each other to best effect. We argue that this requires in silico modelling, an approach for which there is a large literature in the field of evolutionary computation (EC), but which has not really been applied in this way to experimental breeding programmes. EC seeks to optimise measurable outcomes (phenotypic fitnesses) by optimising in silico the mutation, recombination and selection regimes that are used. We review some of the approaches from EC, and compare experimentally, using a biologically relevant in silico landscape, some algorithms that have knowledge of where they are in the (genotypic) search space (G-algorithms) with some (albeit well-tuned ones) that do not (F-algorithms). For the present kinds of landscapes, F- and G-algorithms were broadly comparable in quality and effectiveness, although we recognise that the G-algorithms were not equipped with any ‘prior knowledge’ of epistatic pathway interactions. This use of algorithms based on machine learning has important implications for the optimisation of experimental breeding programmes in the post-genomic era when we shall potentially have access to the full genome sequence of every organism in a breeding population. The non-proprietary code that we have used is made freely available (via Supplementary information). PMID:23185279

  19. Properties of nucleon resonances by means of a genetic algorithm

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fernandez-Ramirez, C.; Moya de Guerra, E.; Instituto de Estructura de la Materia, CSIC, Serrano 123, E-28006 Madrid

    2008-06-15

    We present an optimization scheme that employs a genetic algorithm (GA) to determine the properties of low-lying nucleon excitations within a realistic photo-pion production model based upon an effective Lagrangian. We show that with this modern optimization technique it is possible to reliably assess the parameters of the resonances and the associated error bars as well as to identify weaknesses in the models. To illustrate the problems the optimization process may encounter, we provide results obtained for the nucleon resonances {delta}(1230) and {delta}(1700). The former can be easily isolated and thus has been studied in depth, while the latter ismore » not as well known experimentally.« less

  20. Parameters selection in gene selection using Gaussian kernel support vector machines by genetic algorithm.

    PubMed

    Mao, Yong; Zhou, Xiao-Bo; Pi, Dao-Ying; Sun, You-Xian; Wong, Stephen T C

    2005-10-01

    In microarray-based cancer classification, gene selection is an important issue owing to the large number of variables and small number of samples as well as its non-linearity. It is difficult to get satisfying results by using conventional linear statistical methods. Recursive feature elimination based on support vector machine (SVM RFE) is an effective algorithm for gene selection and cancer classification, which are integrated into a consistent framework. In this paper, we propose a new method to select parameters of the aforementioned algorithm implemented with Gaussian kernel SVMs as better alternatives to the common practice of selecting the apparently best parameters by using a genetic algorithm to search for a couple of optimal parameter. Fast implementation issues for this method are also discussed for pragmatic reasons. The proposed method was tested on two representative hereditary breast cancer and acute leukaemia datasets. The experimental results indicate that the proposed method performs well in selecting genes and achieves high classification accuracies with these genes.

  1. Genetic algorithms

    NASA Technical Reports Server (NTRS)

    Wang, Lui; Bayer, Steven E.

    1991-01-01

    Genetic algorithms are mathematical, highly parallel, adaptive search procedures (i.e., problem solving methods) based loosely on the processes of natural genetics and Darwinian survival of the fittest. Basic genetic algorithms concepts are introduced, genetic algorithm applications are introduced, and results are presented from a project to develop a software tool that will enable the widespread use of genetic algorithm technology.

  2. Simulation and optimization of a pulsating heat pipe using artificial neural network and genetic algorithm

    NASA Astrophysics Data System (ADS)

    Jokar, Ali; Godarzi, Ali Abbasi; Saber, Mohammad; Shafii, Mohammad Behshad

    2016-11-01

    In this paper, a novel approach has been presented to simulate and optimize the pulsating heat pipes (PHPs). The used pulsating heat pipe setup was designed and constructed for this study. Due to the lack of a general mathematical model for exact analysis of the PHPs, a method has been applied for simulation and optimization using the natural algorithms. In this way, the simulator consists of a kind of multilayer perceptron neural network, which is trained by experimental results obtained from our PHP setup. The results show that the complex behavior of PHPs can be successfully described by the non-linear structure of this simulator. The input variables of the neural network are input heat flux to evaporator (q″), filling ratio (FR) and inclined angle (IA) and its output is thermal resistance of PHP. Finally, based upon the simulation results and considering the heat pipe's operating constraints, the optimum operating point of the system is obtained by using genetic algorithm (GA). The experimental results show that the optimum FR (38.25 %), input heat flux to evaporator (39.93 W) and IA (55°) that obtained from GA are acceptable.

  3. Experimental design for estimating unknown groundwater pumping using genetic algorithm and reduced order model

    NASA Astrophysics Data System (ADS)

    Ushijima, Timothy T.; Yeh, William W.-G.

    2013-10-01

    An optimal experimental design algorithm is developed to select locations for a network of observation wells that provide maximum information about unknown groundwater pumping in a confined, anisotropic aquifer. The design uses a maximal information criterion that chooses, among competing designs, the design that maximizes the sum of squared sensitivities while conforming to specified design constraints. The formulated optimization problem is non-convex and contains integer variables necessitating a combinatorial search. Given a realistic large-scale model, the size of the combinatorial search required can make the problem difficult, if not impossible, to solve using traditional mathematical programming techniques. Genetic algorithms (GAs) can be used to perform the global search; however, because a GA requires a large number of calls to a groundwater model, the formulated optimization problem still may be infeasible to solve. As a result, proper orthogonal decomposition (POD) is applied to the groundwater model to reduce its dimensionality. Then, the information matrix in the full model space can be searched without solving the full model. Results from a small-scale test case show identical optimal solutions among the GA, integer programming, and exhaustive search methods. This demonstrates the GA's ability to determine the optimal solution. In addition, the results show that a GA with POD model reduction is several orders of magnitude faster in finding the optimal solution than a GA using the full model. The proposed experimental design algorithm is applied to a realistic, two-dimensional, large-scale groundwater problem. The GA converged to a solution for this large-scale problem.

  4. Bouc-Wen hysteresis model identification using Modified Firefly Algorithm

    NASA Astrophysics Data System (ADS)

    Zaman, Mohammad Asif; Sikder, Urmita

    2015-12-01

    The parameters of Bouc-Wen hysteresis model are identified using a Modified Firefly Algorithm. The proposed algorithm uses dynamic process control parameters to improve its performance. The algorithm is used to find the model parameter values that results in the least amount of error between a set of given data points and points obtained from the Bouc-Wen model. The performance of the algorithm is compared with the performance of conventional Firefly Algorithm, Genetic Algorithm and Differential Evolution algorithm in terms of convergence rate and accuracy. Compared to the other three optimization algorithms, the proposed algorithm is found to have good convergence rate with high degree of accuracy in identifying Bouc-Wen model parameters. Finally, the proposed method is used to find the Bouc-Wen model parameters from experimental data. The obtained model is found to be in good agreement with measured data.

  5. Genetic Algorithms and Local Search

    NASA Technical Reports Server (NTRS)

    Whitley, Darrell

    1996-01-01

    The first part of this presentation is a tutorial level introduction to the principles of genetic search and models of simple genetic algorithms. The second half covers the combination of genetic algorithms with local search methods to produce hybrid genetic algorithms. Hybrid algorithms can be modeled within the existing theoretical framework developed for simple genetic algorithms. An application of a hybrid to geometric model matching is given. The hybrid algorithm yields results that improve on the current state-of-the-art for this problem.

  6. ASPsiRNA: A Resource of ASP-siRNAs Having Therapeutic Potential for Human Genetic Disorders and Algorithm for Prediction of Their Inhibitory Efficacy

    PubMed Central

    Monga, Isha; Qureshi, Abid; Thakur, Nishant; Gupta, Amit Kumar; Kumar, Manoj

    2017-01-01

    Allele-specific siRNAs (ASP-siRNAs) have emerged as promising therapeutic molecules owing to their selectivity to inhibit the mutant allele or associated single-nucleotide polymorphisms (SNPs) sparing the expression of the wild-type counterpart. Thus, a dedicated bioinformatics platform encompassing updated ASP-siRNAs and an algorithm for the prediction of their inhibitory efficacy will be helpful in tackling currently intractable genetic disorders. In the present study, we have developed the ASPsiRNA resource (http://crdd.osdd.net/servers/aspsirna/) covering three components viz (i) ASPsiDb, (ii) ASPsiPred, and (iii) analysis tools like ASP-siOffTar. ASPsiDb is a manually curated database harboring 4543 (including 422 chemically modified) ASP-siRNAs targeting 78 unique genes involved in 51 different diseases. It furnishes comprehensive information from experimental studies on ASP-siRNAs along with multidimensional genetic and clinical information for numerous mutations. ASPsiPred is a two-layered algorithm to predict efficacy of ASP-siRNAs for fully complementary mutant (Effmut) and wild-type allele (Effwild) with one mismatch by ASPsiPredSVM and ASPsiPredmatrix, respectively. In ASPsiPredSVM, 922 unique ASP-siRNAs with experimentally validated quantitative Effmut were used. During 10-fold cross-validation (10nCV) employing various sequence features on the training/testing dataset (T737), the best predictive model achieved a maximum Pearson’s correlation coefficient (PCC) of 0.71. Further, the accuracy of the classifier to predict Effmut against novel genes was assessed by leave one target out cross-validation approach (LOTOCV). ASPsiPredmatrix was constructed from rule-based studies describing the effect of single siRNA:mRNA mismatches on the efficacy at 19 different locations of siRNA. Thus, ASPsiRNA encompasses the first database, prediction algorithm, and off-target analysis tool that is expected to accelerate research in the field of RNAi-based therapeutics for human genetic diseases. PMID:28696921

  7. Appearance and characterization of fruit image textures for quality sorting using wavelet transform and genetic algorithms.

    PubMed

    Khoje, Suchitra

    2018-02-01

    Images of four qualities of mangoes and guavas are evaluated for color and textural features to characterize and classify them, and to model the fruit appearance grading. The paper discusses three approaches to identify most discriminating texture features of both the fruits. In the first approach, fruit's color and texture features are selected using Mahalanobis distance. A total of 20 color features and 40 textural features are extracted for analysis. Using Mahalanobis distance and feature intercorrelation analyses, one best color feature (mean of a* [L*a*b* color space]) and two textural features (energy a*, contrast of H*) are selected as features for Guava while two best color features (R std, H std) and one textural features (energy b*) are selected as features for mangoes with the highest discriminate power. The second approach studies some common wavelet families for searching the best classification model for fruit quality grading. The wavelet features extracted from five basic mother wavelets (db, bior, rbior, Coif, Sym) are explored to characterize fruits texture appearance. In third approach, genetic algorithm is used to select only those color and wavelet texture features that are relevant to the separation of the class, from a large universe of features. The study shows that image color and texture features which were identified using a genetic algorithm can distinguish between various qualities classes of fruits. The experimental results showed that support vector machine classifier is elected for Guava grading with an accuracy of 97.61% and artificial neural network is elected from Mango grading with an accuracy of 95.65%. The proposed method is nondestructive fruit quality assessment method. The experimental results has proven that Genetic algorithm along with wavelet textures feature has potential to discriminate fruit quality. Finally, it can be concluded that discussed method is an accurate, reliable, and objective tool to determine fruit quality namely Mango and Guava, and might be applicable to in-line sorting systems. © 2017 Wiley Periodicals, Inc.

  8. Optimization lighting layout based on gene density improved genetic algorithm for indoor visible light communications

    NASA Astrophysics Data System (ADS)

    Liu, Huanlin; Wang, Xin; Chen, Yong; Kong, Deqian; Xia, Peijie

    2017-05-01

    For indoor visible light communication system, the layout of LED lamps affects the uniformity of the received power on communication plane. In order to find an optimized lighting layout that meets both the lighting needs and communication needs, a gene density genetic algorithm (GDGA) is proposed. In GDGA, a gene indicates a pair of abscissa and ordinate of a LED, and an individual represents a LED layout in the room. The segmented crossover operation and gene mutation strategy based on gene density are put forward to make the received power on communication plane more uniform and increase the population's diversity. A weighted differences function between individuals is designed as the fitness function of GDGA for reserving the population having the useful LED layout genetic information and ensuring the global convergence of GDGA. Comparing square layout and circular layout, with the optimized layout achieved by the GDGA, the power uniformity increases by 83.3%, 83.1% and 55.4%, respectively. Furthermore, the convergence of GDGA is verified compared with evolutionary algorithm (EA). Experimental results show that GDGA can quickly find an approximation of optimal layout.

  9. Indoor high precision three-dimensional positioning system based on visible light communication using modified genetic algorithm

    NASA Astrophysics Data System (ADS)

    Chen, Hao; Guan, Weipeng; Li, Simin; Wu, Yuxiang

    2018-04-01

    To improve the precision of indoor positioning and actualize three-dimensional positioning, a reversed indoor positioning system based on visible light communication (VLC) using genetic algorithm (GA) is proposed. In order to solve the problem of interference between signal sources, CDMA modulation is used. Each light-emitting diode (LED) in the system broadcasts a unique identity (ID) code using CDMA modulation. Receiver receives mixed signal from every LED reference point, by the orthogonality of spreading code in CDMA modulation, ID information and intensity attenuation information from every LED can be obtained. According to positioning principle of received signal strength (RSS), the coordinate of the receiver can be determined. Due to system noise and imperfection of device utilized in the system, distance between receiver and transmitters will deviate from the real value resulting in positioning error. By introducing error correction factors to global parallel search of genetic algorithm, coordinates of the receiver in three-dimensional space can be determined precisely. Both simulation results and experimental results show that in practical application scenarios, the proposed positioning system can realize high precision positioning service.

  10. An Integrated Optimization Design Method Based on Surrogate Modeling Applied to Diverging Duct Design

    NASA Astrophysics Data System (ADS)

    Hanan, Lu; Qiushi, Li; Shaobin, Li

    2016-12-01

    This paper presents an integrated optimization design method in which uniform design, response surface methodology and genetic algorithm are used in combination. In detail, uniform design is used to select the experimental sampling points in the experimental domain and the system performance is evaluated by means of computational fluid dynamics to construct a database. After that, response surface methodology is employed to generate a surrogate mathematical model relating the optimization objective and the design variables. Subsequently, genetic algorithm is adopted and applied to the surrogate model to acquire the optimal solution in the case of satisfying some constraints. The method has been applied to the optimization design of an axisymmetric diverging duct, dealing with three design variables including one qualitative variable and two quantitative variables. The method of modeling and optimization design performs well in improving the duct aerodynamic performance and can be also applied to wider fields of mechanical design and seen as a useful tool for engineering designers, by reducing the design time and computation consumption.

  11. Genetic algorithm learning in a New Keynesian macroeconomic setup.

    PubMed

    Hommes, Cars; Makarewicz, Tomasz; Massaro, Domenico; Smits, Tom

    2017-01-01

    In order to understand heterogeneous behavior amongst agents, empirical data from Learning-to-Forecast (LtF) experiments can be used to construct learning models. This paper follows up on Assenza et al. (2013) by using a Genetic Algorithms (GA) model to replicate the results from their LtF experiment. In this GA model, individuals optimize an adaptive, a trend following and an anchor coefficient in a population of general prediction heuristics. We replicate experimental treatments in a New-Keynesian environment with increasing complexity and use Monte Carlo simulations to investigate how well the model explains the experimental data. We find that the evolutionary learning model is able to replicate the three different types of behavior, i.e. convergence to steady state, stable oscillations and dampened oscillations in the treatments using one GA model. Heterogeneous behavior can thus be explained by an adaptive, anchor and trend extrapolating component and the GA model can be used to explain heterogeneous behavior in LtF experiments with different types of complexity.

  12. Dynamic modelling and parameter estimation of a hydraulic robot manipulator using a multi-objective genetic algorithm

    NASA Astrophysics Data System (ADS)

    Montazeri, A.; West, C.; Monk, S. D.; Taylor, C. J.

    2017-04-01

    This paper concerns the problem of dynamic modelling and parameter estimation for a seven degree of freedom hydraulic manipulator. The laboratory example is a dual-manipulator mobile robotic platform used for research into nuclear decommissioning. In contrast to earlier control model-orientated research using the same machine, the paper develops a nonlinear, mechanistic simulation model that can subsequently be used to investigate physically meaningful disturbances. The second contribution is to optimise the parameters of the new model, i.e. to determine reliable estimates of the physical parameters of a complex robotic arm which are not known in advance. To address the nonlinear and non-convex nature of the problem, the research relies on the multi-objectivisation of an output error single-performance index. The developed algorithm utilises a multi-objective genetic algorithm (GA) in order to find a proper solution. The performance of the model and the GA is evaluated using both simulated (i.e. with a known set of 'true' parameters) and experimental data. Both simulation and experimental results show that multi-objectivisation has improved convergence of the estimated parameters compared to the single-objective output error problem formulation. This is achieved by integrating the validation phase inside the algorithm implicitly and exploiting the inherent structure of the multi-objective GA for this specific system identification problem.

  13. Optimization of Contrast Detection Power with Probabilistic Behavioral Information

    PubMed Central

    Cordes, Dietmar; Herzmann, Grit; Nandy, Rajesh; Curran, Tim

    2012-01-01

    Recent progress in the experimental design for event-related fMRI experiments made it possible to find the optimal stimulus sequence for maximum contrast detection power using a genetic algorithm. In this study, a novel algorithm is proposed for optimization of contrast detection power by including probabilistic behavioral information, based on pilot data, in the genetic algorithm. As a particular application, a recognition memory task is studied and the design matrix optimized for contrasts involving the familiarity of individual items (pictures of objects) and the recollection of qualitative information associated with the items (left/right orientation). Optimization of contrast efficiency is a complicated issue whenever subjects’ responses are not deterministic but probabilistic. Contrast efficiencies are not predictable unless behavioral responses are included in the design optimization. However, available software for design optimization does not include options for probabilistic behavioral constraints. If the anticipated behavioral responses are included in the optimization algorithm, the design is optimal for the assumed behavioral responses, and the resulting contrast efficiency is greater than what either a block design or a random design can achieve. Furthermore, improvements of contrast detection power depend strongly on the behavioral probabilities, the perceived randomness, and the contrast of interest. The present genetic algorithm can be applied to any case in which fMRI contrasts are dependent on probabilistic responses that can be estimated from pilot data. PMID:22326984

  14. Improved Monkey-King Genetic Algorithm for Solving Large Winner Determination in Combinatorial Auction

    NASA Astrophysics Data System (ADS)

    Li, Yuzhong

    Using GA solve the winner determination problem (WDP) with large bids and items, run under different distribution, because the search space is large, constraint complex and it may easy to produce infeasible solution, would affect the efficiency and quality of algorithm. This paper present improved MKGA, including three operator: preprocessing, insert bid and exchange recombination, and use Monkey-king elite preservation strategy. Experimental results show that improved MKGA is better than SGA in population size and computation. The problem that traditional branch and bound algorithm hard to solve, improved MKGA can solve and achieve better effect.

  15. Optimization of Bioactive Ingredient Extraction from Chinese Herbal Medicine Glycyrrhiza glabra: A Comparative Study of Three Optimization Models

    PubMed Central

    Li, Xiaohong; Zhang, Yuyan

    2018-01-01

    The ultraviolet spectrophotometric method is often used for determining the content of glycyrrhizic acid from Chinese herbal medicine Glycyrrhiza glabra. Based on the traditional single variable approach, four extraction parameters of ammonia concentration, ethanol concentration, circumfluence time, and liquid-solid ratio are adopted as the independent extraction variables. In the present work, central composite design of four factors and five levels is applied to design the extraction experiments. Subsequently, the prediction models of response surface methodology, artificial neural networks, and genetic algorithm-artificial neural networks are developed to analyze the obtained experimental data, while the genetic algorithm is utilized to find the optimal extraction parameters for the above well-established models. It is found that the optimization of extraction technology is presented as ammonia concentration 0.595%, ethanol concentration 58.45%, return time 2.5 h, and liquid-solid ratio 11.065 : 1. Under these conditions, the model predictive value is 381.24 mg, the experimental average value is 376.46 mg, and the expectation discrepancy is 4.78 mg. For the first time, a comparative study of these three approaches is conducted for the evaluation and optimization of the effects of the extraction independent variables. Furthermore, it is demonstrated that the combinational method of genetic algorithm and artificial neural networks provides a more reliable and more accurate strategy for design and optimization of glycyrrhizic acid extraction from Glycyrrhiza glabra. PMID:29887907

  16. Optimization of Bioactive Ingredient Extraction from Chinese Herbal Medicine Glycyrrhiza glabra: A Comparative Study of Three Optimization Models.

    PubMed

    Yu, Li; Jin, Weifeng; Li, Xiaohong; Zhang, Yuyan

    2018-01-01

    The ultraviolet spectrophotometric method is often used for determining the content of glycyrrhizic acid from Chinese herbal medicine Glycyrrhiza glabra . Based on the traditional single variable approach, four extraction parameters of ammonia concentration, ethanol concentration, circumfluence time, and liquid-solid ratio are adopted as the independent extraction variables. In the present work, central composite design of four factors and five levels is applied to design the extraction experiments. Subsequently, the prediction models of response surface methodology, artificial neural networks, and genetic algorithm-artificial neural networks are developed to analyze the obtained experimental data, while the genetic algorithm is utilized to find the optimal extraction parameters for the above well-established models. It is found that the optimization of extraction technology is presented as ammonia concentration 0.595%, ethanol concentration 58.45%, return time 2.5 h, and liquid-solid ratio 11.065 : 1. Under these conditions, the model predictive value is 381.24 mg, the experimental average value is 376.46 mg, and the expectation discrepancy is 4.78 mg. For the first time, a comparative study of these three approaches is conducted for the evaluation and optimization of the effects of the extraction independent variables. Furthermore, it is demonstrated that the combinational method of genetic algorithm and artificial neural networks provides a more reliable and more accurate strategy for design and optimization of glycyrrhizic acid extraction from Glycyrrhiza glabra .

  17. Experimental setup for evaluating an adaptive user interface for teleoperation control

    NASA Astrophysics Data System (ADS)

    Wijayasinghe, Indika B.; Peetha, Srikanth; Abubakar, Shamsudeen; Saadatzi, Mohammad Nasser; Cremer, Sven; Popa, Dan O.

    2017-05-01

    A vital part of human interactions with a machine is the control interface, which single-handedly could define the user satisfaction and the efficiency of performing a task. This paper elaborates the implementation of an experimental setup to study an adaptive algorithm that can help the user better tele-operate the robot. The formulation of the adaptive interface and associate learning algorithms are general enough to apply when the mapping between the user controls and the robot actuators is complex and/or ambiguous. The method uses a genetic algorithm to find the optimal parameters that produce the input-output mapping for teleoperation control. In this paper, we describe the experimental setup and associated results that was used to validate the adaptive interface to a differential drive robot from two different input devices; a joystick, and a Myo gesture control armband. Results show that after the learning phase, the interface converges to an intuitive mapping that can help even inexperienced users drive the system to a goal location.

  18. Optimal Draft requirement for vibratory tillage equipment using Genetic Algorithm Technique

    NASA Astrophysics Data System (ADS)

    Rao, Gowripathi; Chaudhary, Himanshu; Singh, Prem

    2018-03-01

    Agriculture is an important sector of Indian economy. Primary and secondary tillage operations are required for any land preparation process. Conventionally different tractor-drawn implements such as mouldboard plough, disc plough, subsoiler, cultivator and disc harrow, etc. are used for primary and secondary manipulations of soils. Among them, oscillatory tillage equipment is one such type which uses vibratory motion for tillage purpose. Several investigators have reported that the requirement for draft consumption in primary tillage implements is more as compared to oscillating one because they are always in contact with soil. Therefore in this paper, an attempt is made to find out the optimal parameters from the experimental data available in the literature to obtain minimum draft consumption through genetic algorithm technique.

  19. Systems Engineering Design Via Experimental Operation Research: Complex Organizational Metric for Programmatic Risk Environments (COMPRE)

    NASA Technical Reports Server (NTRS)

    Mog, Robert A.

    1999-01-01

    Unique and innovative graph theory, neural network, organizational modeling, and genetic algorithms are applied to the design and evolution of programmatic and organizational architectures. Graph theory representations of programs and organizations increase modeling capabilities and flexibility, while illuminating preferable programmatic/organizational design features. Treating programs and organizations as neural networks results in better system synthesis, and more robust data modeling. Organizational modeling using covariance structures enhances the determination of organizational risk factors. Genetic algorithms improve programmatic evolution characteristics, while shedding light on rulebase requirements for achieving specified technological readiness levels, given budget and schedule resources. This program of research improves the robustness and verifiability of systems synthesis tools, including the Complex Organizational Metric for Programmatic Risk Environments (COMPRE).

  20. Systematic design methodology for robust genetic transistors based on I/O specifications via promoter-RBS libraries.

    PubMed

    Lee, Yi-Ying; Hsu, Chih-Yuan; Lin, Ling-Jiun; Chang, Chih-Chun; Cheng, Hsiao-Chun; Yeh, Tsung-Hsien; Hu, Rei-Hsing; Lin, Che; Xie, Zhen; Chen, Bor-Sen

    2013-10-27

    Synthetic genetic transistors are vital for signal amplification and switching in genetic circuits. However, it is still problematic to efficiently select the adequate promoters, Ribosome Binding Sides (RBSs) and inducer concentrations to construct a genetic transistor with the desired linear amplification or switching in the Input/Output (I/O) characteristics for practical applications. Three kinds of promoter-RBS libraries, i.e., a constitutive promoter-RBS library, a repressor-regulated promoter-RBS library and an activator-regulated promoter-RBS library, are constructed for systematic genetic circuit design using the identified kinetic strengths of their promoter-RBS components.According to the dynamic model of genetic transistors, a design methodology for genetic transistors via a Genetic Algorithm (GA)-based searching algorithm is developed to search for a set of promoter-RBS components and adequate concentrations of inducers to achieve the prescribed I/O characteristics of a genetic transistor. Furthermore, according to design specifications for different types of genetic transistors, a look-up table is built for genetic transistor design, from which we could easily select an adequate set of promoter-RBS components and adequate concentrations of external inducers for a specific genetic transistor. This systematic design method will reduce the time spent using trial-and-error methods in the experimental procedure for a genetic transistor with a desired I/O characteristic. We demonstrate the applicability of our design methodology to genetic transistors that have desirable linear amplification or switching by employing promoter-RBS library searching.

  1. Systematic design methodology for robust genetic transistors based on I/O specifications via promoter-RBS libraries

    PubMed Central

    2013-01-01

    Background Synthetic genetic transistors are vital for signal amplification and switching in genetic circuits. However, it is still problematic to efficiently select the adequate promoters, Ribosome Binding Sides (RBSs) and inducer concentrations to construct a genetic transistor with the desired linear amplification or switching in the Input/Output (I/O) characteristics for practical applications. Results Three kinds of promoter-RBS libraries, i.e., a constitutive promoter-RBS library, a repressor-regulated promoter-RBS library and an activator-regulated promoter-RBS library, are constructed for systematic genetic circuit design using the identified kinetic strengths of their promoter-RBS components. According to the dynamic model of genetic transistors, a design methodology for genetic transistors via a Genetic Algorithm (GA)-based searching algorithm is developed to search for a set of promoter-RBS components and adequate concentrations of inducers to achieve the prescribed I/O characteristics of a genetic transistor. Furthermore, according to design specifications for different types of genetic transistors, a look-up table is built for genetic transistor design, from which we could easily select an adequate set of promoter-RBS components and adequate concentrations of external inducers for a specific genetic transistor. Conclusion This systematic design method will reduce the time spent using trial-and-error methods in the experimental procedure for a genetic transistor with a desired I/O characteristic. We demonstrate the applicability of our design methodology to genetic transistors that have desirable linear amplification or switching by employing promoter-RBS library searching. PMID:24160305

  2. Gas ultrasonic flow rate measurement through genetic-ant colony optimization based on the ultrasonic pulse received signal model

    NASA Astrophysics Data System (ADS)

    Hou, Huirang; Zheng, Dandan; Nie, Laixiao

    2015-04-01

    For gas ultrasonic flowmeters, the signals received by ultrasonic sensors are susceptible to noise interference. If signals are mingled with noise, a large error in flow measurement can be caused by triggering mistakenly using the traditional double-threshold method. To solve this problem, genetic-ant colony optimization (GACO) based on the ultrasonic pulse received signal model is proposed. Furthermore, in consideration of the real-time performance of the flow measurement system, the improvement of processing only the first three cycles of the received signals rather than the whole signal is proposed. Simulation results show that the GACO algorithm has the best estimation accuracy and ant-noise ability compared with the genetic algorithm, ant colony optimization, double-threshold and enveloped zero-crossing. Local convergence doesn’t appear with the GACO algorithm until -10 dB. For the GACO algorithm, the converging accuracy and converging speed and the amount of computation are further improved when using the first three cycles (called GACO-3cycles). Experimental results involving actual received signals show that the accuracy of single-gas ultrasonic flow rate measurement can reach 0.5% with GACO-3 cycles, which is better than with the double-threshold method.

  3. Feature selection for neural network based defect classification of ceramic components using high frequency ultrasound.

    PubMed

    Kesharaju, Manasa; Nagarajah, Romesh

    2015-09-01

    The motivation for this research stems from a need for providing a non-destructive testing method capable of detecting and locating any defects and microstructural variations within armour ceramic components before issuing them to the soldiers who rely on them for their survival. The development of an automated ultrasonic inspection based classification system would make possible the checking of each ceramic component and immediately alert the operator about the presence of defects. Generally, in many classification problems a choice of features or dimensionality reduction is significant and simultaneously very difficult, as a substantial computational effort is required to evaluate possible feature subsets. In this research, a combination of artificial neural networks and genetic algorithms are used to optimize the feature subset used in classification of various defects in reaction-sintered silicon carbide ceramic components. Initially wavelet based feature extraction is implemented from the region of interest. An Artificial Neural Network classifier is employed to evaluate the performance of these features. Genetic Algorithm based feature selection is performed. Principal Component Analysis is a popular technique used for feature selection and is compared with the genetic algorithm based technique in terms of classification accuracy and selection of optimal number of features. The experimental results confirm that features identified by Principal Component Analysis lead to improved performance in terms of classification percentage with 96% than Genetic algorithm with 94%. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Problem solving with genetic algorithms and Splicer

    NASA Technical Reports Server (NTRS)

    Bayer, Steven E.; Wang, Lui

    1991-01-01

    Genetic algorithms are highly parallel, adaptive search procedures (i.e., problem-solving methods) loosely based on the processes of population genetics and Darwinian survival of the fittest. Genetic algorithms have proven useful in domains where other optimization techniques perform poorly. The main purpose of the paper is to discuss a NASA-sponsored software development project to develop a general-purpose tool for using genetic algorithms. The tool, called Splicer, can be used to solve a wide variety of optimization problems and is currently available from NASA and COSMIC. This discussion is preceded by an introduction to basic genetic algorithm concepts and a discussion of genetic algorithm applications.

  5. Discovery of a metastable Al20Sm4 phase

    NASA Astrophysics Data System (ADS)

    Ye, Z.; Zhang, F.; Sun, Y.; Mendelev, M. I.; Ott, R. T.; Park, E.; Besser, M. F.; Kramer, M. J.; Ding, Z.; Wang, C.-Z.; Ho, K.-M.

    2015-03-01

    We present an efficient genetic algorithm, integrated with experimental diffraction data, to solve a nanoscale metastable Al20Sm4 phase that evolves during crystallization of an amorphous magnetron sputtered Al90Sm10 alloy. The excellent match between calculated and experimental X-ray diffraction patterns confirms an accurate description of this metastable phase. Molecular dynamic simulations of crystal growth from the liquid phase predict the formation of disordered defects in the devitrified crystal.

  6. Optimized hyperspectral band selection using hybrid genetic algorithm and gravitational search algorithm

    NASA Astrophysics Data System (ADS)

    Zhang, Aizhu; Sun, Genyun; Wang, Zhenjie

    2015-12-01

    The serious information redundancy in hyperspectral images (HIs) cannot contribute to the data analysis accuracy, instead it require expensive computational resources. Consequently, to identify the most useful and valuable information from the HIs, thereby improve the accuracy of data analysis, this paper proposed a novel hyperspectral band selection method using the hybrid genetic algorithm and gravitational search algorithm (GA-GSA). In the proposed method, the GA-GSA is mapped to the binary space at first. Then, the accuracy of the support vector machine (SVM) classifier and the number of selected spectral bands are utilized to measure the discriminative capability of the band subset. Finally, the band subset with the smallest number of spectral bands as well as covers the most useful and valuable information is obtained. To verify the effectiveness of the proposed method, studies conducted on an AVIRIS image against two recently proposed state-of-the-art GSA variants are presented. The experimental results revealed the superiority of the proposed method and indicated that the method can indeed considerably reduce data storage costs and efficiently identify the band subset with stable and high classification precision.

  7. Genetic algorithm based approach to investigate doped metal oxide materials: Application to lanthanide-doped ceria

    NASA Astrophysics Data System (ADS)

    Hooper, James; Ismail, Arif; Giorgi, Javier B.; Woo, Tom K.

    2010-06-01

    A genetic algorithm (GA)-inspired method to effectively map out low-energy configurations of doped metal oxide materials is presented. Specialized mating and mutation operations that do not alter the identity of the parent metal oxide have been incorporated to efficiently sample the metal dopant and oxygen vacancy sites. The search algorithms have been tested on lanthanide-doped ceria (L=Sm,Gd,Lu) with various dopant concentrations. Using both classical and first-principles density-functional-theory (DFT) potentials, we have shown the methodology reproduces the results of recent systematic searches of doped ceria at low concentrations (3.2% L2O3 ) and identifies low-energy structures of concentrated samarium-doped ceria (3.8% and 6.6% L2O3 ) which relate to the experimental and theoretical findings published thus far. We introduce a tandem classical/DFT GA algorithm in which an inexpensive classical potential is first used to generate a fit gene pool of structures to enhance the overall efficiency of the computationally demanding DFT-based GA search.

  8. Experience with a Genetic Algorithm Implemented on a Multiprocessor Computer

    NASA Technical Reports Server (NTRS)

    Plassman, Gerald E.; Sobieszczanski-Sobieski, Jaroslaw

    2000-01-01

    Numerical experiments were conducted to find out the extent to which a Genetic Algorithm (GA) may benefit from a multiprocessor implementation, considering, on one hand, that analyses of individual designs in a population are independent of each other so that they may be executed concurrently on separate processors, and, on the other hand, that there are some operations in a GA that cannot be so distributed. The algorithm experimented with was based on a gaussian distribution rather than bit exchange in the GA reproductive mechanism, and the test case was a hub frame structure of up to 1080 design variables. The experimentation engaging up to 128 processors confirmed expectations of radical elapsed time reductions comparing to a conventional single processor implementation. It also demonstrated that the time spent in the non-distributable parts of the algorithm and the attendant cross-processor communication may have a very detrimental effect on the efficient utilization of the multiprocessor machine and on the number of processors that can be used effectively in a concurrent manner. Three techniques were devised and tested to mitigate that effect, resulting in efficiency increasing to exceed 99 percent.

  9. Genetic algorithms using SISAL parallel programming language

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tejada, S.

    1994-05-06

    Genetic algorithms are a mathematical optimization technique developed by John Holland at the University of Michigan [1]. The SISAL programming language possesses many of the characteristics desired to implement genetic algorithms. SISAL is a deterministic, functional programming language which is inherently parallel. Because SISAL is functional and based on mathematical concepts, genetic algorithms can be efficiently translated into the language. Several of the steps involved in genetic algorithms, such as mutation, crossover, and fitness evaluation, can be parallelized using SISAL. In this paper I will l discuss the implementation and performance of parallel genetic algorithms in SISAL.

  10. Single Neuron Optimization as a Basis for Accurate Biophysical Modeling: The Case of Cerebellar Granule Cells.

    PubMed

    Masoli, Stefano; Rizza, Martina F; Sgritta, Martina; Van Geit, Werner; Schürmann, Felix; D'Angelo, Egidio

    2017-01-01

    In realistic neuronal modeling, once the ionic channel complement has been defined, the maximum ionic conductance (G i-max ) values need to be tuned in order to match the firing pattern revealed by electrophysiological recordings. Recently, selection/mutation genetic algorithms have been proposed to efficiently and automatically tune these parameters. Nonetheless, since similar firing patterns can be achieved through different combinations of G i-max values, it is not clear how well these algorithms approximate the corresponding properties of real cells. Here we have evaluated the issue by exploiting a unique opportunity offered by the cerebellar granule cell (GrC), which is electrotonically compact and has therefore allowed the direct experimental measurement of ionic currents. Previous models were constructed using empirical tuning of G i-max values to match the original data set. Here, by using repetitive discharge patterns as a template, the optimization procedure yielded models that closely approximated the experimental G i-max values. These models, in addition to repetitive firing, captured additional features, including inward rectification, near-threshold oscillations, and resonance, which were not used as features. Thus, parameter optimization using genetic algorithms provided an efficient modeling strategy for reconstructing the biophysical properties of neurons and for the subsequent reconstruction of large-scale neuronal network models.

  11. A Bee Evolutionary Guiding Nondominated Sorting Genetic Algorithm II for Multiobjective Flexible Job-Shop Scheduling.

    PubMed

    Deng, Qianwang; Gong, Guiliang; Gong, Xuran; Zhang, Like; Liu, Wei; Ren, Qinghua

    2017-01-01

    Flexible job-shop scheduling problem (FJSP) is an NP-hard puzzle which inherits the job-shop scheduling problem (JSP) characteristics. This paper presents a bee evolutionary guiding nondominated sorting genetic algorithm II (BEG-NSGA-II) for multiobjective FJSP (MO-FJSP) with the objectives to minimize the maximal completion time, the workload of the most loaded machine, and the total workload of all machines. It adopts a two-stage optimization mechanism during the optimizing process. In the first stage, the NSGA-II algorithm with T iteration times is first used to obtain the initial population N , in which a bee evolutionary guiding scheme is presented to exploit the solution space extensively. In the second stage, the NSGA-II algorithm with GEN iteration times is used again to obtain the Pareto-optimal solutions. In order to enhance the searching ability and avoid the premature convergence, an updating mechanism is employed in this stage. More specifically, its population consists of three parts, and each of them changes with the iteration times. What is more, numerical simulations are carried out which are based on some published benchmark instances. Finally, the effectiveness of the proposed BEG-NSGA-II algorithm is shown by comparing the experimental results and the results of some well-known algorithms already existed.

  12. A Bee Evolutionary Guiding Nondominated Sorting Genetic Algorithm II for Multiobjective Flexible Job-Shop Scheduling

    PubMed Central

    Deng, Qianwang; Gong, Xuran; Zhang, Like; Liu, Wei; Ren, Qinghua

    2017-01-01

    Flexible job-shop scheduling problem (FJSP) is an NP-hard puzzle which inherits the job-shop scheduling problem (JSP) characteristics. This paper presents a bee evolutionary guiding nondominated sorting genetic algorithm II (BEG-NSGA-II) for multiobjective FJSP (MO-FJSP) with the objectives to minimize the maximal completion time, the workload of the most loaded machine, and the total workload of all machines. It adopts a two-stage optimization mechanism during the optimizing process. In the first stage, the NSGA-II algorithm with T iteration times is first used to obtain the initial population N, in which a bee evolutionary guiding scheme is presented to exploit the solution space extensively. In the second stage, the NSGA-II algorithm with GEN iteration times is used again to obtain the Pareto-optimal solutions. In order to enhance the searching ability and avoid the premature convergence, an updating mechanism is employed in this stage. More specifically, its population consists of three parts, and each of them changes with the iteration times. What is more, numerical simulations are carried out which are based on some published benchmark instances. Finally, the effectiveness of the proposed BEG-NSGA-II algorithm is shown by comparing the experimental results and the results of some well-known algorithms already existed. PMID:28458687

  13. Evolvable Neuronal Paths: A Novel Basis for Information and Search in the Brain

    PubMed Central

    Fernando, Chrisantha; Vasas, Vera; Szathmáry, Eörs; Husbands, Phil

    2011-01-01

    We propose a previously unrecognized kind of informational entity in the brain that is capable of acting as the basis for unlimited hereditary variation in neuronal networks. This unit is a path of activity through a network of neurons, analogous to a path taken through a hidden Markov model. To prove in principle the capabilities of this new kind of informational substrate, we show how a population of paths can be used as the hereditary material for a neuronally implemented genetic algorithm, (the swiss-army knife of black-box optimization techniques) which we have proposed elsewhere could operate at somatic timescales in the brain. We compare this to the same genetic algorithm that uses a standard ‘genetic’ informational substrate, i.e. non-overlapping discrete genotypes, on a range of optimization problems. A path evolution algorithm (PEA) is defined as any algorithm that implements natural selection of paths in a network substrate. A PEA is a previously unrecognized type of natural selection that is well suited for implementation by biological neuronal networks with structural plasticity. The important similarities and differences between a standard genetic algorithm and a PEA are considered. Whilst most experiments are conducted on an abstract network model, at the conclusion of the paper a slightly more realistic neuronal implementation of a PEA is outlined based on Izhikevich spiking neurons. Finally, experimental predictions are made for the identification of such informational paths in the brain. PMID:21887266

  14. Focusing light through strongly scattering media using genetic algorithm with SBR discriminant

    NASA Astrophysics Data System (ADS)

    Zhang, Bin; Zhang, Zhenfeng; Feng, Qi; Liu, Zhipeng; Lin, Chengyou; Ding, Yingchun

    2018-02-01

    In this paper, we have experimentally demonstrated light focusing through strongly scattering media by performing binary amplitude optimization with a genetic algorithm. In the experiments, we control 160 000 mirrors of digital micromirror device to modulate and optimize the light transmission paths in the strongly scattering media. We replace the universal target-position-intensity (TPI) discriminant with signal-to-background ratio (SBR) discriminant in genetic algorithm. With 400 incident segments, a relative enhancement value of 17.5% with a ground glass diffuser is achieved, which is higher than the theoretical value of 1/(2π )≈ 15.9 % for binary amplitude optimization. According to our repetitive experiments, we conclude that, with the same segment number, the enhancement for the SBR discriminant is always higher than that for the TPI discriminant, which results from the background-weakening effect of SBR discriminant. In addition, with the SBR discriminant, the diameters of the focus can be changed ranging from 7 to 70 μm at arbitrary positions. Besides, multiple foci with high enhancement are obtained. Our work provides a meaningful reference for the study of binary amplitude optimization in the wavefront shaping field.

  15. Application of genetic algorithm for the simultaneous identification of atmospheric pollution sources

    NASA Astrophysics Data System (ADS)

    Cantelli, A.; D'Orta, F.; Cattini, A.; Sebastianelli, F.; Cedola, L.

    2015-08-01

    A computational model is developed for retrieving the positions and the emission rates of unknown pollution sources, under steady state conditions, starting from the measurements of the concentration of the pollutants. The approach is based on the minimization of a fitness function employing a genetic algorithm paradigm. The model is tested considering both pollutant concentrations generated through a Gaussian model in 25 points in a 3-D test case domain (1000m × 1000m × 50 m) and experimental data such as the Prairie Grass field experiments data in which about 600 receptors were located along five concentric semicircle arcs and the Fusion Field Trials 2007. The results show that the computational model is capable to efficiently retrieve up to three different unknown sources.

  16. Directed Field Ionization: A Genetic Algorithm for Evolving Electric Field Pulses

    NASA Astrophysics Data System (ADS)

    Kang, Xinyue; Rowley, Zoe A.; Carroll, Thomas J.; Noel, Michael W.

    2017-04-01

    When an ionizing electric field pulse is applied to a Rydberg atom, the electron's amplitude traverses many avoided crossings among the Stark levels as the field increases. The resulting superposition determines the shape of the time resolved field ionization spectrum at a detector. An engineered electric field pulse that sweeps back and forth through avoided crossings can control the phase evolution so as to determine the electron's path through the Stark map. In the region of n = 35 in rubidium there are hundreds of potential avoided crossings; this yields a large space of possible pulses. We use a genetic algorithm to search this space and evolve electric field pulses to direct the ionization of the Rydberg electron in rubidium. We present the algorithm along with a comparison of simulated and experimental results. This work was supported by the National Science Foundation under Grants No. 1607335 and No. 1607377 and used the Extreme Science and Engineering Discovery Environment (XSEDE), which is supported by National Science Foundation Grant Number OCI-1053575.

  17. Artificial Intelligence Techniques to Optimize the EDC/NHS-Mediated Immobilization of Cellulase on Eudragit L-100

    PubMed Central

    Zhang, Yu; Xu, Jing-Liang; Yuan, Zhen-Hong; Qi, Wei; Liu, Yun-Yun; He, Min-Chao

    2012-01-01

    Two artificial intelligence techniques, namely artificial neural network (ANN) and genetic algorithm (GA) were combined to be used as a tool for optimizing the covalent immobilization of cellulase on a smart polymer, Eudragit L-100. 1-Ethyl-3-(3-dimethyllaminopropyl) carbodiimide (EDC) concentration, N-hydroxysuccinimide (NHS) concentration and coupling time were taken as independent variables, and immobilization efficiency was taken as the response. The data of the central composite design were used to train ANN by back-propagation algorithm, and the result showed that the trained ANN fitted the data accurately (correlation coefficient R2 = 0.99). Then a maximum immobilization efficiency of 88.76% was searched by genetic algorithm at a EDC concentration of 0.44%, NHS concentration of 0.37% and a coupling time of 2.22 h, where the experimental value was 87.97 ± 6.45%. The application of ANN based optimization by GA is quite successful. PMID:22942683

  18. Enhanced α-amylase production by a marine protist, Ulkenia sp. using response surface methodology and genetic algorithm.

    PubMed

    Shirodkar, Priyanka V; Muraleedharan, Usha Devi

    2017-11-26

    Amylases are a group of enzymes with a wide variety of industrial applications. Enhancement of α-amylase production from the marine protists, thraustochytrids has been attempted for the first time by applying statistical-based experimental designs using response surface methodology (RSM) and genetic algorithm (GA) for optimization of the most influencing process variables. A full factorial central composite experimental design was used to study the cumulative interactive effect of nutritional components viz., glucose, corn starch, and yeast extract. RSM was performed on two objectives, that is, growth of Ulkenia sp. AH-2 (ATCC® PRA-296) and α-amylase activity. When GA was conducted for maximization of the enzyme activity, the optimal α-amylase activity was found to be 71.20 U/mL which was close to that obtained by RSM (71.93 U/mL), both of which were in agreement with the predicted value of 72.37 U/mL. Optimal growth at the optimized process variables was found to be 1.89A 660nm . The optimized medium increased α-amylase production by 1.2-fold.

  19. Decentralized diagnostics based on a distributed micro-genetic algorithm for transducer networks monitoring large experimental systems.

    PubMed

    Arpaia, P; Cimmino, P; Girone, M; La Commara, G; Maisto, D; Manna, C; Pezzetti, M

    2014-09-01

    Evolutionary approach to centralized multiple-faults diagnostics is extended to distributed transducer networks monitoring large experimental systems. Given a set of anomalies detected by the transducers, each instance of the multiple-fault problem is formulated as several parallel communicating sub-tasks running on different transducers, and thus solved one-by-one on spatially separated parallel processes. A micro-genetic algorithm merges evaluation time efficiency, arising from a small-size population distributed on parallel-synchronized processors, with the effectiveness of centralized evolutionary techniques due to optimal mix of exploitation and exploration. In this way, holistic view and effectiveness advantages of evolutionary global diagnostics are combined with reliability and efficiency benefits of distributed parallel architectures. The proposed approach was validated both (i) by simulation at CERN, on a case study of a cold box for enhancing the cryogeny diagnostics of the Large Hadron Collider, and (ii) by experiments, under the framework of the industrial research project MONDIEVOB (Building Remote Monitoring and Evolutionary Diagnostics), co-funded by EU and the company Del Bo srl, Napoli, Italy.

  20. Reconstructing Genetic Regulatory Networks Using Two-Step Algorithms with the Differential Equation Models of Neural Networks.

    PubMed

    Chen, Chi-Kan

    2017-07-26

    The identification of genetic regulatory networks (GRNs) provides insights into complex cellular processes. A class of recurrent neural networks (RNNs) captures the dynamics of GRN. Algorithms combining the RNN and machine learning schemes were proposed to reconstruct small-scale GRNs using gene expression time series. We present new GRN reconstruction methods with neural networks. The RNN is extended to a class of recurrent multilayer perceptrons (RMLPs) with latent nodes. Our methods contain two steps: the edge rank assignment step and the network construction step. The former assigns ranks to all possible edges by a recursive procedure based on the estimated weights of wires of RNN/RMLP (RE RNN /RE RMLP ), and the latter constructs a network consisting of top-ranked edges under which the optimized RNN simulates the gene expression time series. The particle swarm optimization (PSO) is applied to optimize the parameters of RNNs and RMLPs in a two-step algorithm. The proposed RE RNN -RNN and RE RMLP -RNN algorithms are tested on synthetic and experimental gene expression time series of small GRNs of about 10 genes. The experimental time series are from the studies of yeast cell cycle regulated genes and E. coli DNA repair genes. The unstable estimation of RNN using experimental time series having limited data points can lead to fairly arbitrary predicted GRNs. Our methods incorporate RNN and RMLP into a two-step structure learning procedure. Results show that the RE RMLP using the RMLP with a suitable number of latent nodes to reduce the parameter dimension often result in more accurate edge ranks than the RE RNN using the regularized RNN on short simulated time series. Combining by a weighted majority voting rule the networks derived by the RE RMLP -RNN using different numbers of latent nodes in step one to infer the GRN, the method performs consistently and outperforms published algorithms for GRN reconstruction on most benchmark time series. The framework of two-step algorithms can potentially incorporate with different nonlinear differential equation models to reconstruct the GRN.

  1. Optimal Design of Passive Power Filters Based on Pseudo-parallel Genetic Algorithm

    NASA Astrophysics Data System (ADS)

    Li, Pei; Li, Hongbo; Gao, Nannan; Niu, Lin; Guo, Liangfeng; Pei, Ying; Zhang, Yanyan; Xu, Minmin; Chen, Kerui

    2017-05-01

    The economic costs together with filter efficiency are taken as targets to optimize the parameter of passive filter. Furthermore, the method of combining pseudo-parallel genetic algorithm with adaptive genetic algorithm is adopted in this paper. In the early stages pseudo-parallel genetic algorithm is introduced to increase the population diversity, and adaptive genetic algorithm is used in the late stages to reduce the workload. At the same time, the migration rate of pseudo-parallel genetic algorithm is improved to change with population diversity adaptively. Simulation results show that the filter designed by the proposed method has better filtering effect with lower economic cost, and can be used in engineering.

  2. A Novel Hybrid Classification Model of Genetic Algorithms, Modified k-Nearest Neighbor and Developed Backpropagation Neural Network

    PubMed Central

    Salari, Nader; Shohaimi, Shamarina; Najafi, Farid; Nallappan, Meenakshii; Karishnarajah, Isthrinayagy

    2014-01-01

    Among numerous artificial intelligence approaches, k-Nearest Neighbor algorithms, genetic algorithms, and artificial neural networks are considered as the most common and effective methods in classification problems in numerous studies. In the present study, the results of the implementation of a novel hybrid feature selection-classification model using the above mentioned methods are presented. The purpose is benefitting from the synergies obtained from combining these technologies for the development of classification models. Such a combination creates an opportunity to invest in the strength of each algorithm, and is an approach to make up for their deficiencies. To develop proposed model, with the aim of obtaining the best array of features, first, feature ranking techniques such as the Fisher's discriminant ratio and class separability criteria were used to prioritize features. Second, the obtained results that included arrays of the top-ranked features were used as the initial population of a genetic algorithm to produce optimum arrays of features. Third, using a modified k-Nearest Neighbor method as well as an improved method of backpropagation neural networks, the classification process was advanced based on optimum arrays of the features selected by genetic algorithms. The performance of the proposed model was compared with thirteen well-known classification models based on seven datasets. Furthermore, the statistical analysis was performed using the Friedman test followed by post-hoc tests. The experimental findings indicated that the novel proposed hybrid model resulted in significantly better classification performance compared with all 13 classification methods. Finally, the performance results of the proposed model was benchmarked against the best ones reported as the state-of-the-art classifiers in terms of classification accuracy for the same data sets. The substantial findings of the comprehensive comparative study revealed that performance of the proposed model in terms of classification accuracy is desirable, promising, and competitive to the existing state-of-the-art classification models. PMID:25419659

  3. Capacity improvement using simulation optimization approaches: A case study in the thermotechnology industry

    NASA Astrophysics Data System (ADS)

    Yelkenci Köse, Simge; Demir, Leyla; Tunalı, Semra; Türsel Eliiyi, Deniz

    2015-02-01

    In manufacturing systems, optimal buffer allocation has a considerable impact on capacity improvement. This study presents a simulation optimization procedure to solve the buffer allocation problem in a heat exchanger production plant so as to improve the capacity of the system. For optimization, three metaheuristic-based search algorithms, i.e. a binary-genetic algorithm (B-GA), a binary-simulated annealing algorithm (B-SA) and a binary-tabu search algorithm (B-TS), are proposed. These algorithms are integrated with the simulation model of the production line. The simulation model, which captures the stochastic and dynamic nature of the production line, is used as an evaluation function for the proposed metaheuristics. The experimental study with benchmark problem instances from the literature and the real-life problem show that the proposed B-TS algorithm outperforms B-GA and B-SA in terms of solution quality.

  4. ASPsiRNA: A Resource of ASP-siRNAs Having Therapeutic Potential for Human Genetic Disorders and Algorithm for Prediction of Their Inhibitory Efficacy.

    PubMed

    Monga, Isha; Qureshi, Abid; Thakur, Nishant; Gupta, Amit Kumar; Kumar, Manoj

    2017-09-07

    Allele-specific siRNAs (ASP-siRNAs) have emerged as promising therapeutic molecules owing to their selectivity to inhibit the mutant allele or associated single-nucleotide polymorphisms (SNPs) sparing the expression of the wild-type counterpart. Thus, a dedicated bioinformatics platform encompassing updated ASP-siRNAs and an algorithm for the prediction of their inhibitory efficacy will be helpful in tackling currently intractable genetic disorders. In the present study, we have developed the ASPsiRNA resource (http://crdd.osdd.net/servers/aspsirna/) covering three components viz (i) ASPsiDb , (ii) ASPsiPred , and (iii) analysis tools like ASP-siOffTar ASPsiDb is a manually curated database harboring 4543 (including 422 chemically modified) ASP-siRNAs targeting 78 unique genes involved in 51 different diseases. It furnishes comprehensive information from experimental studies on ASP-siRNAs along with multidimensional genetic and clinical information for numerous mutations. ASPsiPred is a two-layered algorithm to predict efficacy of ASP-siRNAs for fully complementary mutant (Eff mut ) and wild-type allele (Eff wild ) with one mismatch by ASPsiPred SVM and ASPsiPred matrix , respectively. In ASPsiPred SVM , 922 unique ASP-siRNAs with experimentally validated quantitative Eff mut were used. During 10-fold cross-validation (10nCV) employing various sequence features on the training/testing dataset (T737), the best predictive model achieved a maximum Pearson's correlation coefficient (PCC) of 0.71. Further, the accuracy of the classifier to predict Eff mut against novel genes was assessed by leave one target out cross-validation approach (LOTOCV). ASPsiPred matrix was constructed from rule-based studies describing the effect of single siRNA:mRNA mismatches on the efficacy at 19 different locations of siRNA. Thus, ASPsiRNA encompasses the first database, prediction algorithm, and off-target analysis tool that is expected to accelerate research in the field of RNAi-based therapeutics for human genetic diseases. Copyright © 2017 Monga et al.

  5. A hybrid artificial bee colony algorithm for numerical function optimization

    NASA Astrophysics Data System (ADS)

    Alqattan, Zakaria N.; Abdullah, Rosni

    2015-02-01

    Artificial Bee Colony (ABC) algorithm is one of the swarm intelligence algorithms; it has been introduced by Karaboga in 2005. It is a meta-heuristic optimization search algorithm inspired from the intelligent foraging behavior of the honey bees in nature. Its unique search process made it as one of the most competitive algorithm with some other search algorithms in the area of optimization, such as Genetic algorithm (GA) and Particle Swarm Optimization (PSO). However, the ABC performance of the local search process and the bee movement or the solution improvement equation still has some weaknesses. The ABC is good in avoiding trapping at the local optimum but it spends its time searching around unpromising random selected solutions. Inspired by the PSO, we propose a Hybrid Particle-movement ABC algorithm called HPABC, which adapts the particle movement process to improve the exploration of the original ABC algorithm. Numerical benchmark functions were used in order to experimentally test the HPABC algorithm. The results illustrate that the HPABC algorithm can outperform the ABC algorithm in most of the experiments (75% better in accuracy and over 3 times faster).

  6. a Gsa-Svm Hybrid System for Classification of Binary Problems

    NASA Astrophysics Data System (ADS)

    Sarafrazi, Soroor; Nezamabadi-pour, Hossein; Barahman, Mojgan

    2011-06-01

    This paperhybridizesgravitational search algorithm (GSA) with support vector machine (SVM) and made a novel GSA-SVM hybrid system to improve the classification accuracy in binary problems. GSA is an optimization heuristic toolused to optimize the value of SVM kernel parameter (in this paper, radial basis function (RBF) is chosen as the kernel function). The experimental results show that this newapproach can achieve high classification accuracy and is comparable to or better than the particle swarm optimization (PSO)-SVM and genetic algorithm (GA)-SVM, which are two hybrid systems for classification.

  7. Parametric optimization of multiple quality characteristics in laser cutting of Inconel-718 by using hybrid approach of multiple regression analysis and genetic algorithm

    NASA Astrophysics Data System (ADS)

    Shrivastava, Prashant Kumar; Pandey, Arun Kumar

    2018-06-01

    Inconel-718 has found high demand in different industries due to their superior mechanical properties. The traditional cutting methods are facing difficulties for cutting these alloys due to their low thermal potential, lower elasticity and high chemical compatibility at inflated temperature. The challenges of machining and/or finishing of unusual shapes and/or sizes in these materials have also faced by traditional machining. Laser beam cutting may be applied for the miniaturization and ultra-precision cutting and/or finishing by appropriate control of different process parameter. This paper present multi-objective optimization the kerf deviation, kerf width and kerf taper in the laser cutting of Incone-718 sheet. The second order regression models have been developed for different quality characteristics by using the experimental data obtained through experimentation. The regression models have been used as objective function for multi-objective optimization based on the hybrid approach of multiple regression analysis and genetic algorithm. The comparison of optimization results to experimental results shows an improvement of 88%, 10.63% and 42.15% in kerf deviation, kerf width and kerf taper, respectively. Finally, the effects of different process parameters on quality characteristics have also been discussed.

  8. Novel and efficient tag SNPs selection algorithms.

    PubMed

    Chen, Wen-Pei; Hung, Che-Lun; Tsai, Suh-Jen Jane; Lin, Yaw-Ling

    2014-01-01

    SNPs are the most abundant forms of genetic variations amongst species; the association studies between complex diseases and SNPs or haplotypes have received great attention. However, these studies are restricted by the cost of genotyping all SNPs; thus, it is necessary to find smaller subsets, or tag SNPs, representing the rest of the SNPs. In fact, the existing tag SNP selection algorithms are notoriously time-consuming. An efficient algorithm for tag SNP selection was presented, which was applied to analyze the HapMap YRI data. The experimental results show that the proposed algorithm can achieve better performance than the existing tag SNP selection algorithms; in most cases, this proposed algorithm is at least ten times faster than the existing methods. In many cases, when the redundant ratio of the block is high, the proposed algorithm can even be thousands times faster than the previously known methods. Tools and web services for haplotype block analysis integrated by hadoop MapReduce framework are also developed using the proposed algorithm as computation kernels.

  9. Statistical analysis for validating ACO-KNN algorithm as feature selection in sentiment analysis

    NASA Astrophysics Data System (ADS)

    Ahmad, Siti Rohaidah; Yusop, Nurhafizah Moziyana Mohd; Bakar, Azuraliza Abu; Yaakub, Mohd Ridzwan

    2017-10-01

    This research paper aims to propose a hybrid of ant colony optimization (ACO) and k-nearest neighbor (KNN) algorithms as feature selections for selecting and choosing relevant features from customer review datasets. Information gain (IG), genetic algorithm (GA), and rough set attribute reduction (RSAR) were used as baseline algorithms in a performance comparison with the proposed algorithm. This paper will also discuss the significance test, which was used to evaluate the performance differences between the ACO-KNN, IG-GA, and IG-RSAR algorithms. This study evaluated the performance of the ACO-KNN algorithm using precision, recall, and F-score, which were validated using the parametric statistical significance tests. The evaluation process has statistically proven that this ACO-KNN algorithm has been significantly improved compared to the baseline algorithms. The evaluation process has statistically proven that this ACO-KNN algorithm has been significantly improved compared to the baseline algorithms. In addition, the experimental results have proven that the ACO-KNN can be used as a feature selection technique in sentiment analysis to obtain quality, optimal feature subset that can represent the actual data in customer review data.

  10. Studies on the Parametric Effects of Plasma Arc Welding of 2205 Duplex Stainless Steel

    NASA Astrophysics Data System (ADS)

    Selva Bharathi, R.; Siva Shanmugam, N.; Murali Kannan, R.; Arungalai Vendan, S.

    2018-03-01

    This research study attempts to create an optimized parametric window by employing Taguchi algorithm for Plasma Arc Welding (PAW) of 2 mm thick 2205 duplex stainless steel. The parameters considered for experimentation and optimization are the welding current, welding speed and pilot arc length respectively. The experimentation involves the parameters variation and subsequently recording the depth of penetration and bead width. Welding current of 60-70 A, welding speed of 250-300 mm/min and pilot arc length of 1-2 mm are the range between which the parameters are varied. Design of experiments is used for the experimental trials. Back propagation neural network, Genetic algorithm and Taguchi techniques are used for predicting the bead width, depth of penetration and validated with experimentally achieved results which were in good agreement. Additionally, micro-structural characterizations are carried out to examine the weld quality. The extrapolation of these optimized parametric values yield enhanced weld strength with cost and time reduction.

  11. G/SPLINES: A hybrid of Friedman's Multivariate Adaptive Regression Splines (MARS) algorithm with Holland's genetic algorithm

    NASA Technical Reports Server (NTRS)

    Rogers, David

    1991-01-01

    G/SPLINES are a hybrid of Friedman's Multivariable Adaptive Regression Splines (MARS) algorithm with Holland's Genetic Algorithm. In this hybrid, the incremental search is replaced by a genetic search. The G/SPLINE algorithm exhibits performance comparable to that of the MARS algorithm, requires fewer least squares computations, and allows significantly larger problems to be considered.

  12. Comparison of genetic algorithms with conjugate gradient methods

    NASA Technical Reports Server (NTRS)

    Bosworth, J. L.; Foo, N. Y.; Zeigler, B. P.

    1972-01-01

    Genetic algorithms for mathematical function optimization are modeled on search strategies employed in natural adaptation. Comparisons of genetic algorithms with conjugate gradient methods, which were made on an IBM 1800 digital computer, show that genetic algorithms display superior performance over gradient methods for functions which are poorly behaved mathematically, for multimodal functions, and for functions obscured by additive random noise. Genetic methods offer performance comparable to gradient methods for many of the standard functions.

  13. Recurrent neural network-based modeling of gene regulatory network using elephant swarm water search algorithm.

    PubMed

    Mandal, Sudip; Saha, Goutam; Pal, Rajat Kumar

    2017-08-01

    Correct inference of genetic regulations inside a cell from the biological database like time series microarray data is one of the greatest challenges in post genomic era for biologists and researchers. Recurrent Neural Network (RNN) is one of the most popular and simple approach to model the dynamics as well as to infer correct dependencies among genes. Inspired by the behavior of social elephants, we propose a new metaheuristic namely Elephant Swarm Water Search Algorithm (ESWSA) to infer Gene Regulatory Network (GRN). This algorithm is mainly based on the water search strategy of intelligent and social elephants during drought, utilizing the different types of communication techniques. Initially, the algorithm is tested against benchmark small and medium scale artificial genetic networks without and with presence of different noise levels and the efficiency was observed in term of parametric error, minimum fitness value, execution time, accuracy of prediction of true regulation, etc. Next, the proposed algorithm is tested against the real time gene expression data of Escherichia Coli SOS Network and results were also compared with others state of the art optimization methods. The experimental results suggest that ESWSA is very efficient for GRN inference problem and performs better than other methods in many ways.

  14. Software For Genetic Algorithms

    NASA Technical Reports Server (NTRS)

    Wang, Lui; Bayer, Steve E.

    1992-01-01

    SPLICER computer program is genetic-algorithm software tool used to solve search and optimization problems. Provides underlying framework and structure for building genetic-algorithm application program. Written in Think C.

  15. Research on strategy and optimization method of PRT empty vehicles resource allocation based on traffic demand forecast

    NASA Astrophysics Data System (ADS)

    Xiang, Yu; Tao, Cheng

    2018-05-01

    During the operation of the personal rapid transit system(PRT), the empty vehicle resources is distributed unevenly because of different passenger demand. In order to maintain the balance between supply and demand, and to meet the passenger needs of the ride, PRT empty vehicle resource allocation model is constructed based on the future demand forecasted by historical demand in this paper. The improved genetic algorithm is implied in distribution of the empty vehicle which can reduce the customers waiting time and improve the operation efficiency of the PRT system so that all passengers can take the PRT vehicles in the shortest time. The experimental result shows that the improved genetic algorithm can allocate the empty vehicle from the system level optimally, and realize the distribution of the empty vehicle resources reasonably in the system.

  16. Evolutionary Initial Poses of Reduced D.O.F’s Quadruped Robot

    NASA Astrophysics Data System (ADS)

    Iida, Ken-Ichi; Nakata, Yoshitaka; Hira, Toshio; Kamano, Takuya; Suzuki, Takayuki

    In this paper, an application of genetic algorithm for generation of evolutionary initial poses of a quadrupedal robot which reduced degrees of freedom is described. To reduce degree of freedom, each leg of the robot has a slider-crank mechanism and is driven by an actuator. Furthermore we introduced the forward movement mode and the rotating mode because the omnidirection movement should be made possible. To generate the suitable initial pose, the initial angle of four legs are coded under gray code and tuned by an estimation function in each mode with the genetic algorithm. As a result of generation, the cooperation of the legs is realized to move toward the omnidirection. The experimental results demonstrate that the proposed scheme is effective for generation of the suitable initial poses and the robot can walk smoothly with the generated patterns.

  17. SoftLab: A Soft-Computing Software for Experimental Research with Commercialization Aspects

    NASA Technical Reports Server (NTRS)

    Akbarzadeh-T, M.-R.; Shaikh, T. S.; Ren, J.; Hubbell, Rob; Kumbla, K. K.; Jamshidi, M

    1998-01-01

    SoftLab is a software environment for research and development in intelligent modeling/control using soft-computing paradigms such as fuzzy logic, neural networks, genetic algorithms, and genetic programs. SoftLab addresses the inadequacies of the existing soft-computing software by supporting comprehensive multidisciplinary functionalities from management tools to engineering systems. Furthermore, the built-in features help the user process/analyze information more efficiently by a friendly yet powerful interface, and will allow the user to specify user-specific processing modules, hence adding to the standard configuration of the software environment.

  18. Transitioning from Targeted to Comprehensive Mass Spectrometry Using Genetic Algorithms.

    PubMed

    Jaffe, Jacob D; Feeney, Caitlin M; Patel, Jinal; Lu, Xiaodong; Mani, D R

    2016-11-01

    Targeted proteomic assays are becoming increasingly popular because of their robust quantitative applications enabled by internal standardization, and they can be routinely executed on high performance mass spectrometry instrumentation. However, these assays are typically limited to 100s of analytes per experiment. Considerable time and effort are often expended in obtaining and preparing samples prior to targeted analyses. It would be highly desirable to detect and quantify 1000s of analytes in such samples using comprehensive mass spectrometry techniques (e.g., SWATH and DIA) while retaining a high degree of quantitative rigor for analytes with matched internal standards. Experimentally, it is facile to port a targeted assay to a comprehensive data acquisition technique. However, data analysis challenges arise from this strategy concerning agreement of results from the targeted and comprehensive approaches. Here, we present the use of genetic algorithms to overcome these challenges in order to configure hybrid targeted/comprehensive MS assays. The genetic algorithms are used to select precursor-to-fragment transitions that maximize the agreement in quantification between the targeted and the comprehensive methods. We find that the algorithm we used provided across-the-board improvement in the quantitative agreement between the targeted assay data and the hybrid comprehensive/targeted assay that we developed, as measured by parameters of linear models fitted to the results. We also found that the algorithm could perform at least as well as an independently-trained mass spectrometrist in accomplishing this task. We hope that this approach will be a useful tool in the development of quantitative approaches for comprehensive proteomics techniques. Graphical Abstract ᅟ.

  19. Transitioning from Targeted to Comprehensive Mass Spectrometry Using Genetic Algorithms

    NASA Astrophysics Data System (ADS)

    Jaffe, Jacob D.; Feeney, Caitlin M.; Patel, Jinal; Lu, Xiaodong; Mani, D. R.

    2016-11-01

    Targeted proteomic assays are becoming increasingly popular because of their robust quantitative applications enabled by internal standardization, and they can be routinely executed on high performance mass spectrometry instrumentation. However, these assays are typically limited to 100s of analytes per experiment. Considerable time and effort are often expended in obtaining and preparing samples prior to targeted analyses. It would be highly desirable to detect and quantify 1000s of analytes in such samples using comprehensive mass spectrometry techniques (e.g., SWATH and DIA) while retaining a high degree of quantitative rigor for analytes with matched internal standards. Experimentally, it is facile to port a targeted assay to a comprehensive data acquisition technique. However, data analysis challenges arise from this strategy concerning agreement of results from the targeted and comprehensive approaches. Here, we present the use of genetic algorithms to overcome these challenges in order to configure hybrid targeted/comprehensive MS assays. The genetic algorithms are used to select precursor-to-fragment transitions that maximize the agreement in quantification between the targeted and the comprehensive methods. We find that the algorithm we used provided across-the-board improvement in the quantitative agreement between the targeted assay data and the hybrid comprehensive/targeted assay that we developed, as measured by parameters of linear models fitted to the results. We also found that the algorithm could perform at least as well as an independently-trained mass spectrometrist in accomplishing this task. We hope that this approach will be a useful tool in the development of quantitative approaches for comprehensive proteomics techniques.

  20. New knowledge-based genetic algorithm for excavator boom structural optimization

    NASA Astrophysics Data System (ADS)

    Hua, Haiyan; Lin, Shuwen

    2014-03-01

    Due to the insufficiency of utilizing knowledge to guide the complex optimal searching, existing genetic algorithms fail to effectively solve excavator boom structural optimization problem. To improve the optimization efficiency and quality, a new knowledge-based real-coded genetic algorithm is proposed. A dual evolution mechanism combining knowledge evolution with genetic algorithm is established to extract, handle and utilize the shallow and deep implicit constraint knowledge to guide the optimal searching of genetic algorithm circularly. Based on this dual evolution mechanism, knowledge evolution and population evolution can be connected by knowledge influence operators to improve the configurability of knowledge and genetic operators. Then, the new knowledge-based selection operator, crossover operator and mutation operator are proposed to integrate the optimal process knowledge and domain culture to guide the excavator boom structural optimization. Eight kinds of testing algorithms, which include different genetic operators, are taken as examples to solve the structural optimization of a medium-sized excavator boom. By comparing the results of optimization, it is shown that the algorithm including all the new knowledge-based genetic operators can more remarkably improve the evolutionary rate and searching ability than other testing algorithms, which demonstrates the effectiveness of knowledge for guiding optimal searching. The proposed knowledge-based genetic algorithm by combining multi-level knowledge evolution with numerical optimization provides a new effective method for solving the complex engineering optimization problem.

  1. An optimized resistor pattern for temperature gradient control in microfluidics

    NASA Astrophysics Data System (ADS)

    Selva, Bertrand; Marchalot, Julien; Jullien, Marie-Caroline

    2009-06-01

    In this paper, we demonstrate the possibility of generating high-temperature gradients with a linear temperature profile when heating is provided in situ. Thanks to improved optimization algorithms, the shape of resistors, which constitute the heating source, is optimized by applying the genetic algorithm NSGA-II (acronym for the non-dominated sorting genetic algorithm) (Deb et al 2002 IEEE Trans. Evol. Comput. 6 2). Experimental validation of the linear temperature profile within the cavity is carried out using a thermally sensitive fluorophore, called Rhodamine B (Ross et al 2001 Anal. Chem. 73 4117-23, Erickson et al 2003 Lab Chip 3 141-9). The high level of agreement obtained between experimental and numerical results serves to validate the accuracy of this method for generating highly controlled temperature profiles. In the field of actuation, such a device is of potential interest since it allows for controlling bubbles or droplets moving by means of thermocapillary effects (Baroud et al 2007 Phys. Rev. E 75 046302). Digital microfluidics is a critical area in the field of microfluidics (Dreyfus et al 2003 Phys. Rev. Lett. 90 14) as well as in the so-called lab-on-a-chip technology. Through an example, the large application potential of such a technique is demonstrated, which entails handling a single bubble driven along a cavity using simple and tunable embedded resistors.

  2. Design a software real-time operation platform for wave piercing catamarans motion control using linear quadratic regulator based genetic algorithm.

    PubMed

    Liang, Lihua; Yuan, Jia; Zhang, Songtao; Zhao, Peng

    2018-01-01

    This work presents optimal linear quadratic regulator (LQR) based on genetic algorithm (GA) to solve the two degrees of freedom (2 DoF) motion control problem in head seas for wave piercing catamarans (WPC). The proposed LQR based GA control strategy is to select optimal weighting matrices (Q and R). The seakeeping performance of WPC based on proposed algorithm is challenged because of multi-input multi-output (MIMO) system of uncertain coefficient problems. Besides the kinematical constraint problems of WPC, the external conditions must be considered, like the sea disturbance and the actuators (a T-foil and two flaps) control. Moreover, this paper describes the MATLAB and LabVIEW software plats to simulate the reduction effects of WPC. Finally, the real-time (RT) NI CompactRIO embedded controller is selected to test the effectiveness of the actuators based on proposed techniques. In conclusion, simulation and experimental results prove the correctness of the proposed algorithm. The percentage of heave and pitch reductions are more than 18% in different high speeds and bad sea conditions. And the results also verify the feasibility of NI CompactRIO embedded controller.

  3. Design a software real-time operation platform for wave piercing catamarans motion control using linear quadratic regulator based genetic algorithm

    PubMed Central

    Liang, Lihua; Zhang, Songtao; Zhao, Peng

    2018-01-01

    This work presents optimal linear quadratic regulator (LQR) based on genetic algorithm (GA) to solve the two degrees of freedom (2 DoF) motion control problem in head seas for wave piercing catamarans (WPC). The proposed LQR based GA control strategy is to select optimal weighting matrices (Q and R). The seakeeping performance of WPC based on proposed algorithm is challenged because of multi-input multi-output (MIMO) system of uncertain coefficient problems. Besides the kinematical constraint problems of WPC, the external conditions must be considered, like the sea disturbance and the actuators (a T-foil and two flaps) control. Moreover, this paper describes the MATLAB and LabVIEW software plats to simulate the reduction effects of WPC. Finally, the real-time (RT) NI CompactRIO embedded controller is selected to test the effectiveness of the actuators based on proposed techniques. In conclusion, simulation and experimental results prove the correctness of the proposed algorithm. The percentage of heave and pitch reductions are more than 18% in different high speeds and bad sea conditions. And the results also verify the feasibility of NI CompactRIO embedded controller. PMID:29709008

  4. The fatigue life prediction of aluminium alloy using genetic algorithm and neural network

    NASA Astrophysics Data System (ADS)

    Susmikanti, Mike

    2013-09-01

    The behavior of the fatigue life of the industrial materials is very important. In many cases, the material with experiencing fatigue life cannot be avoided, however, there are many ways to control their behavior. Many investigations of the fatigue life phenomena of alloys have been done, but it is high cost and times consuming computation. This paper report the modeling and simulation approaches to predict the fatigue life behavior of Aluminum Alloys and resolves some problems of computation. First, the simulation using genetic algorithm was utilized to optimize the load to obtain the stress values. These results can be used to provide N-cycle fatigue life of the material. Furthermore, the experimental data was applied as input data in the neural network learning, while the samples data were applied for testing of the training data. Finally, the multilayer perceptron algorithm is applied to predict whether the given data sets in accordance with the fatigue life of the alloy. To achieve rapid convergence, the Levenberg-Marquardt algorithm was also employed. The simulations results shows that the fatigue behaviors of aluminum under pressure can be predicted. In addition, implementation of neural networks successfully identified a model for material fatigue life.

  5. An Orthogonal Evolutionary Algorithm With Learning Automata for Multiobjective Optimization.

    PubMed

    Dai, Cai; Wang, Yuping; Ye, Miao; Xue, Xingsi; Liu, Hailin

    2016-12-01

    Research on multiobjective optimization problems becomes one of the hottest topics of intelligent computation. In order to improve the search efficiency of an evolutionary algorithm and maintain the diversity of solutions, in this paper, the learning automata (LA) is first used for quantization orthogonal crossover (QOX), and a new fitness function based on decomposition is proposed to achieve these two purposes. Based on these, an orthogonal evolutionary algorithm with LA for complex multiobjective optimization problems with continuous variables is proposed. The experimental results show that in continuous states, the proposed algorithm is able to achieve accurate Pareto-optimal sets and wide Pareto-optimal fronts efficiently. Moreover, the comparison with the several existing well-known algorithms: nondominated sorting genetic algorithm II, decomposition-based multiobjective evolutionary algorithm, decomposition-based multiobjective evolutionary algorithm with an ensemble of neighborhood sizes, multiobjective optimization by LA, and multiobjective immune algorithm with nondominated neighbor-based selection, on 15 multiobjective benchmark problems, shows that the proposed algorithm is able to find more accurate and evenly distributed Pareto-optimal fronts than the compared ones.

  6. Ensemble of hybrid genetic algorithm for two-dimensional phase unwrapping

    NASA Astrophysics Data System (ADS)

    Balakrishnan, D.; Quan, C.; Tay, C. J.

    2013-06-01

    The phase unwrapping is the final and trickiest step in any phase retrieval technique. Phase unwrapping by artificial intelligence methods (optimization algorithms) such as hybrid genetic algorithm, reverse simulated annealing, particle swarm optimization, minimum cost matching showed better results than conventional phase unwrapping methods. In this paper, Ensemble of hybrid genetic algorithm with parallel populations is proposed to solve the branch-cut phase unwrapping problem. In a single populated hybrid genetic algorithm, the selection, cross-over and mutation operators are applied to obtain new population in every generation. The parameters and choice of operators will affect the performance of the hybrid genetic algorithm. The ensemble of hybrid genetic algorithm will facilitate to have different parameters set and different choice of operators simultaneously. Each population will use different set of parameters and the offspring of each population will compete against the offspring of all other populations, which use different set of parameters. The effectiveness of proposed algorithm is demonstrated by phase unwrapping examples and advantages of the proposed method are discussed.

  7. Mobile robot dynamic path planning based on improved genetic algorithm

    NASA Astrophysics Data System (ADS)

    Wang, Yong; Zhou, Heng; Wang, Ying

    2017-08-01

    In dynamic unknown environment, the dynamic path planning of mobile robots is a difficult problem. In this paper, a dynamic path planning method based on genetic algorithm is proposed, and a reward value model is designed to estimate the probability of dynamic obstacles on the path, and the reward value function is applied to the genetic algorithm. Unique coding techniques reduce the computational complexity of the algorithm. The fitness function of the genetic algorithm fully considers three factors: the security of the path, the shortest distance of the path and the reward value of the path. The simulation results show that the proposed genetic algorithm is efficient in all kinds of complex dynamic environments.

  8. Fitting membrane resistance along with action potential shape in cardiac myocytes improves convergence: application of a multi-objective parallel genetic algorithm.

    PubMed

    Kaur, Jaspreet; Nygren, Anders; Vigmond, Edward J

    2014-01-01

    Fitting parameter sets of non-linear equations in cardiac single cell ionic models to reproduce experimental behavior is a time consuming process. The standard procedure is to adjust maximum channel conductances in ionic models to reproduce action potentials (APs) recorded in isolated cells. However, vastly different sets of parameters can produce similar APs. Furthermore, even with an excellent AP match in case of single cell, tissue behaviour may be very different. We hypothesize that this uncertainty can be reduced by additionally fitting membrane resistance (Rm). To investigate the importance of Rm, we developed a genetic algorithm approach which incorporated Rm data calculated at a few points in the cycle, in addition to AP morphology. Performance was compared to a genetic algorithm using only AP morphology data. The optimal parameter sets and goodness of fit as computed by the different methods were compared. First, we fit an ionic model to itself, starting from a random parameter set. Next, we fit the AP of one ionic model to that of another. Finally, we fit an ionic model to experimentally recorded rabbit action potentials. Adding the extra objective (Rm, at a few voltages) to the AP fit, lead to much better convergence. Typically, a smaller MSE (mean square error, defined as the average of the squared error between the target AP and AP that is to be fitted) was achieved in one fifth of the number of generations compared to using only AP data. Importantly, the variability in fit parameters was also greatly reduced, with many parameters showing an order of magnitude decrease in variability. Adding Rm to the objective function improves the robustness of fitting, better preserving tissue level behavior, and should be incorporated.

  9. An Efficient Rank Based Approach for Closest String and Closest Substring

    PubMed Central

    2012-01-01

    This paper aims to present a new genetic approach that uses rank distance for solving two known NP-hard problems, and to compare rank distance with other distance measures for strings. The two NP-hard problems we are trying to solve are closest string and closest substring. For each problem we build a genetic algorithm and we describe the genetic operations involved. Both genetic algorithms use a fitness function based on rank distance. We compare our algorithms with other genetic algorithms that use different distance measures, such as Hamming distance or Levenshtein distance, on real DNA sequences. Our experiments show that the genetic algorithms based on rank distance have the best results. PMID:22675483

  10. A hybrid genetic algorithm for resolving closely spaced objects

    NASA Technical Reports Server (NTRS)

    Abbott, R. J.; Lillo, W. E.; Schulenburg, N.

    1995-01-01

    A hybrid genetic algorithm is described for performing the difficult optimization task of resolving closely spaced objects appearing in space based and ground based surveillance data. This application of genetic algorithms is unusual in that it uses a powerful domain-specific operation as a genetic operator. Results of applying the algorithm to real data from telescopic observations of a star field are presented.

  11. Genetic Algorithm Tuned Fuzzy Logic for Gliding Return Trajectories

    NASA Technical Reports Server (NTRS)

    Burchett, Bradley T.

    2003-01-01

    The problem of designing and flying a trajectory for successful recovery of a reusable launch vehicle is tackled using fuzzy logic control with genetic algorithm optimization. The plant is approximated by a simplified three degree of freedom non-linear model. A baseline trajectory design and guidance algorithm consisting of several Mamdani type fuzzy controllers is tuned using a simple genetic algorithm. Preliminary results show that the performance of the overall system is shown to improve with genetic algorithm tuning.

  12. Evolutionary tabu search strategies for the simultaneous registration of multiple atomic structures in cryo-EM reconstructions.

    PubMed

    Rusu, Mirabela; Birmanns, Stefan

    2010-04-01

    A structural characterization of multi-component cellular assemblies is essential to explain the mechanisms governing biological function. Macromolecular architectures may be revealed by integrating information collected from various biophysical sources - for instance, by interpreting low-resolution electron cryomicroscopy reconstructions in relation to the crystal structures of the constituent fragments. A simultaneous registration of multiple components is beneficial when building atomic models as it introduces additional spatial constraints to facilitate the native placement inside the map. The high-dimensional nature of such a search problem prevents the exhaustive exploration of all possible solutions. Here we introduce a novel method based on genetic algorithms, for the efficient exploration of the multi-body registration search space. The classic scheme of a genetic algorithm was enhanced with new genetic operations, tabu search and parallel computing strategies and validated on a benchmark of synthetic and experimental cryo-EM datasets. Even at a low level of detail, for example 35-40 A, the technique successfully registered multiple component biomolecules, measuring accuracies within one order of magnitude of the nominal resolutions of the maps. The algorithm was implemented using the Sculptor molecular modeling framework, which also provides a user-friendly graphical interface and enables an instantaneous, visual exploration of intermediate solutions. (c) 2009 Elsevier Inc. All rights reserved.

  13. Focusing light through strongly scattering media by controlling binary amplitude optimization using genetic algorithm

    NASA Astrophysics Data System (ADS)

    Liu, Zhipeng; Zhang, Bin; Feng, Qi; Chen, Zhaoyang; Lin, Chengyou; Ding, Yingchun

    2017-06-01

    Focusing light through strongly scattering media plays an important role in biomedical imaging and therapy. Here, we experimentally demonstrate light focusing through ZnO sample by controlling binary amplitude optimization using genetic algorithm. In the experiment, we use a Micro Electro-Mechanical System (MEMS)-based digital micromirror device (DMD) which is in amplitude-only modulation mode. The DMD consists of 1920×1080 square mirrors that can be independently controlled to reflect light to a desired position. We control only 160 thousand mirrors which are divided into 400 segments to modulate light focusing through the scattering media using advanced genetic algorithm. Light intensity at the target position is enhanced up to 50+/-5 times the average speckle intensity. The diameters of focusing spot can be changed ranging from 7 μm to 70 μm at arbitrary positions and multiple foci are obtained simultaneously. The spatial arrangement of multiple foci can be flexibly controlled. The advantage of DMDs lies in their switching speed up to 30 kHz, which has the potential to generate a focus in an ultra-short period of time. Our work provides a reference for the study of high speed wavefront shaping that is required in vivo tissues imaging.

  14. Intelligent design optimization of a shape-memory-alloy-actuated reconfigurable wing

    NASA Astrophysics Data System (ADS)

    Lagoudas, Dimitris C.; Strelec, Justin K.; Yen, John; Khan, Mohammad A.

    2000-06-01

    The unique thermal and mechanical properties offered by shape memory alloys (SMAs) present exciting possibilities in the field of aerospace engineering. When properly trained, SMA wires act as linear actuators by contracting when heated and returning to their original shape when cooled. It has been shown experimentally that the overall shape of an airfoil can be altered by activating several attached SMA wire actuators. This shape-change can effectively increase the efficiency of a wing in flight at several different flow regimes. To determine the necessary placement of these wire actuators within the wing, an optimization method that incorporates a fully-coupled structural, thermal, and aerodynamic analysis has been utilized. Due to the complexity of the fully-coupled analysis, intelligent optimization methods such as genetic algorithms have been used to efficiently converge to an optimal solution. The genetic algorithm used in this case is a hybrid version with global search and optimization capabilities augmented by the simplex method as a local search technique. For the reconfigurable wing, each chromosome represents a realizable airfoil configuration and its genes are the SMA actuators, described by their location and maximum transformation strain. The genetic algorithm has been used to optimize this design problem to maximize the lift-to-drag ratio for a reconfigured airfoil shape.

  15. Solving Energy-Aware Real-Time Tasks Scheduling Problem with Shuffled Frog Leaping Algorithm on Heterogeneous Platforms

    PubMed Central

    Zhang, Weizhe; Bai, Enci; He, Hui; Cheng, Albert M.K.

    2015-01-01

    Reducing energy consumption is becoming very important in order to keep battery life and lower overall operational costs for heterogeneous real-time multiprocessor systems. In this paper, we first formulate this as a combinatorial optimization problem. Then, a successful meta-heuristic, called Shuffled Frog Leaping Algorithm (SFLA) is proposed to reduce the energy consumption. Precocity remission and local optimal avoidance techniques are proposed to avoid the precocity and improve the solution quality. Convergence acceleration significantly reduces the search time. Experimental results show that the SFLA-based energy-aware meta-heuristic uses 30% less energy than the Ant Colony Optimization (ACO) algorithm, and 60% less energy than the Genetic Algorithm (GA) algorithm. Remarkably, the running time of the SFLA-based meta-heuristic is 20 and 200 times less than ACO and GA, respectively, for finding the optimal solution. PMID:26110406

  16. Learning Intelligent Genetic Algorithms Using Japanese Nonograms

    ERIC Educational Resources Information Center

    Tsai, Jinn-Tsong; Chou, Ping-Yi; Fang, Jia-Cen

    2012-01-01

    An intelligent genetic algorithm (IGA) is proposed to solve Japanese nonograms and is used as a method in a university course to learn evolutionary algorithms. The IGA combines the global exploration capabilities of a canonical genetic algorithm (CGA) with effective condensed encoding, improved fitness function, and modified crossover and…

  17. Classification of Alzheimer's disease and prediction of mild cognitive impairment-to-Alzheimer's conversion from structural magnetic resource imaging using feature ranking and a genetic algorithm.

    PubMed

    Beheshti, Iman; Demirel, Hasan; Matsuda, Hiroshi

    2017-04-01

    We developed a novel computer-aided diagnosis (CAD) system that uses feature-ranking and a genetic algorithm to analyze structural magnetic resonance imaging data; using this system, we can predict conversion of mild cognitive impairment (MCI)-to-Alzheimer's disease (AD) at between one and three years before clinical diagnosis. The CAD system was developed in four stages. First, we used a voxel-based morphometry technique to investigate global and local gray matter (GM) atrophy in an AD group compared with healthy controls (HCs). Regions with significant GM volume reduction were segmented as volumes of interest (VOIs). Second, these VOIs were used to extract voxel values from the respective atrophy regions in AD, HC, stable MCI (sMCI) and progressive MCI (pMCI) patient groups. The voxel values were then extracted into a feature vector. Third, at the feature-selection stage, all features were ranked according to their respective t-test scores and a genetic algorithm designed to find the optimal feature subset. The Fisher criterion was used as part of the objective function in the genetic algorithm. Finally, the classification was carried out using a support vector machine (SVM) with 10-fold cross validation. We evaluated the proposed automatic CAD system by applying it to baseline values from the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset (160 AD, 162 HC, 65 sMCI and 71 pMCI subjects). The experimental results indicated that the proposed system is capable of distinguishing between sMCI and pMCI patients, and would be appropriate for practical use in a clinical setting. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. A Hybrid Color Space for Skin Detection Using Genetic Algorithm Heuristic Search and Principal Component Analysis Technique

    PubMed Central

    2015-01-01

    Color is one of the most prominent features of an image and used in many skin and face detection applications. Color space transformation is widely used by researchers to improve face and skin detection performance. Despite the substantial research efforts in this area, choosing a proper color space in terms of skin and face classification performance which can address issues like illumination variations, various camera characteristics and diversity in skin color tones has remained an open issue. This research proposes a new three-dimensional hybrid color space termed SKN by employing the Genetic Algorithm heuristic and Principal Component Analysis to find the optimal representation of human skin color in over seventeen existing color spaces. Genetic Algorithm heuristic is used to find the optimal color component combination setup in terms of skin detection accuracy while the Principal Component Analysis projects the optimal Genetic Algorithm solution to a less complex dimension. Pixel wise skin detection was used to evaluate the performance of the proposed color space. We have employed four classifiers including Random Forest, Naïve Bayes, Support Vector Machine and Multilayer Perceptron in order to generate the human skin color predictive model. The proposed color space was compared to some existing color spaces and shows superior results in terms of pixel-wise skin detection accuracy. Experimental results show that by using Random Forest classifier, the proposed SKN color space obtained an average F-score and True Positive Rate of 0.953 and False Positive Rate of 0.0482 which outperformed the existing color spaces in terms of pixel wise skin detection accuracy. The results also indicate that among the classifiers used in this study, Random Forest is the most suitable classifier for pixel wise skin detection applications. PMID:26267377

  19. Global search in photoelectron diffraction structure determination using genetic algorithms

    NASA Astrophysics Data System (ADS)

    Viana, M. L.; Díez Muiño, R.; Soares, E. A.; Van Hove, M. A.; de Carvalho, V. E.

    2007-11-01

    Photoelectron diffraction (PED) is an experimental technique widely used to perform structural determinations of solid surfaces. Similarly to low-energy electron diffraction (LEED), structural determination by PED requires a fitting procedure between the experimental intensities and theoretical results obtained through simulations. Multiple scattering has been shown to be an effective approach for making such simulations. The quality of the fit can be quantified through the so-called R-factor. Therefore, the fitting procedure is, indeed, an R-factor minimization problem. However, the topography of the R-factor as a function of the structural and non-structural surface parameters to be determined is complex, and the task of finding the global minimum becomes tough, particularly for complex structures in which many parameters have to be adjusted. In this work we investigate the applicability of the genetic algorithm (GA) global optimization method to this problem. The GA is based on the evolution of species, and makes use of concepts such as crossover, elitism and mutation to perform the search. We show results of its application in the structural determination of three different systems: the Cu(111) surface through the use of energy-scanned experimental curves; the Ag(110)-c(2 × 2)-Sb system, in which a theory-theory fit was performed; and the Ag(111) surface for which angle-scanned experimental curves were used. We conclude that the GA is a highly efficient method to search for global minima in the optimization of the parameters that best fit the experimental photoelectron diffraction intensities to the theoretical ones.

  20. A Parallel Genetic Algorithm for Automated Electronic Circuit Design

    NASA Technical Reports Server (NTRS)

    Long, Jason D.; Colombano, Silvano P.; Haith, Gary L.; Stassinopoulos, Dimitris

    2000-01-01

    Parallelized versions of genetic algorithms (GAs) are popular primarily for three reasons: the GA is an inherently parallel algorithm, typical GA applications are very compute intensive, and powerful computing platforms, especially Beowulf-style computing clusters, are becoming more affordable and easier to implement. In addition, the low communication bandwidth required allows the use of inexpensive networking hardware such as standard office ethernet. In this paper we describe a parallel GA and its use in automated high-level circuit design. Genetic algorithms are a type of trial-and-error search technique that are guided by principles of Darwinian evolution. Just as the genetic material of two living organisms can intermix to produce offspring that are better adapted to their environment, GAs expose genetic material, frequently strings of 1s and Os, to the forces of artificial evolution: selection, mutation, recombination, etc. GAs start with a pool of randomly-generated candidate solutions which are then tested and scored with respect to their utility. Solutions are then bred by probabilistically selecting high quality parents and recombining their genetic representations to produce offspring solutions. Offspring are typically subjected to a small amount of random mutation. After a pool of offspring is produced, this process iterates until a satisfactory solution is found or an iteration limit is reached. Genetic algorithms have been applied to a wide variety of problems in many fields, including chemistry, biology, and many engineering disciplines. There are many styles of parallelism used in implementing parallel GAs. One such method is called the master-slave or processor farm approach. In this technique, slave nodes are used solely to compute fitness evaluations (the most time consuming part). The master processor collects fitness scores from the nodes and performs the genetic operators (selection, reproduction, variation, etc.). Because of dependency issues in the GA, it is possible to have idle processors. However, as long as the load at each processing node is similar, the processors are kept busy nearly all of the time. In applying GAs to circuit design, a suitable genetic representation 'is that of a circuit-construction program. We discuss one such circuit-construction programming language and show how evolution can generate useful analog circuit designs. This language has the desirable property that virtually all sets of combinations of primitives result in valid circuit graphs. Our system allows circuit size (number of devices), circuit topology, and device values to be evolved. Using a parallel genetic algorithm and circuit simulation software, we present experimental results as applied to three analog filter and two amplifier design tasks. For example, a figure shows an 85 dB amplifier design evolved by our system, and another figure shows the performance of that circuit (gain and frequency response). In all tasks, our system is able to generate circuits that achieve the target specifications.

  1. Hybrid genetic algorithm with an adaptive penalty function for fitting multimodal experimental data: application to exchange-coupled non-Kramers binuclear iron active sites.

    PubMed

    Beaser, Eric; Schwartz, Jennifer K; Bell, Caleb B; Solomon, Edward I

    2011-09-26

    A Genetic Algorithm (GA) is a stochastic optimization technique based on the mechanisms of biological evolution. These algorithms have been successfully applied in many fields to solve a variety of complex nonlinear problems. While they have been used with some success in chemical problems such as fitting spectroscopic and kinetic data, many have avoided their use due to the unconstrained nature of the fitting process. In engineering, this problem is now being addressed through incorporation of adaptive penalty functions, but their transfer to other fields has been slow. This study updates the Nanakorrn Adaptive Penalty function theory, expanding its validity beyond maximization problems to minimization as well. The expanded theory, using a hybrid genetic algorithm with an adaptive penalty function, was applied to analyze variable temperature variable field magnetic circular dichroism (VTVH MCD) spectroscopic data collected on exchange coupled Fe(II)Fe(II) enzyme active sites. The data obtained are described by a complex nonlinear multimodal solution space with at least 6 to 13 interdependent variables and are costly to search efficiently. The use of the hybrid GA is shown to improve the probability of detecting the global optimum. It also provides large gains in computational and user efficiency. This method allows a full search of a multimodal solution space, greatly improving the quality and confidence in the final solution obtained, and can be applied to other complex systems such as fitting of other spectroscopic or kinetics data.

  2. View-Invariant Gait Recognition Through Genetic Template Segmentation

    NASA Astrophysics Data System (ADS)

    Isaac, Ebenezer R. H. P.; Elias, Susan; Rajagopalan, Srinivasan; Easwarakumar, K. S.

    2017-08-01

    Template-based model-free approach provides by far the most successful solution to the gait recognition problem in literature. Recent work discusses how isolating the head and leg portion of the template increase the performance of a gait recognition system making it robust against covariates like clothing and carrying conditions. However, most involve a manual definition of the boundaries. The method we propose, the genetic template segmentation (GTS), employs the genetic algorithm to automate the boundary selection process. This method was tested on the GEI, GEnI and AEI templates. GEI seems to exhibit the best result when segmented with our approach. Experimental results depict that our approach significantly outperforms the existing implementations of view-invariant gait recognition.

  3. Boiler-turbine control system design using a genetic algorithm

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dimeo, R.; Lee, K.Y.

    1995-12-01

    This paper discusses the application of a genetic algorithm to control system design for a boiler-turbine plant. In particular the authors study the ability of the genetic algorithm to develop a proportional-integral (PI) controller and a state feedback controller for a non-linear multi-input/multi-output (MIMO) plant model. The plant model is presented along with a discussion of the inherent difficulties in such controller development. A sketch of the genetic algorithm (GA) is presented and its strategy as a method of control system design is discussed. Results are presented for two different control systems that have been designed with the genetic algorithm.

  4. Partial discharge localization in power transformers based on the sequential quadratic programming-genetic algorithm adopting acoustic emission techniques

    NASA Astrophysics Data System (ADS)

    Liu, Hua-Long; Liu, Hua-Dong

    2014-10-01

    Partial discharge (PD) in power transformers is one of the prime reasons resulting in insulation degradation and power faults. Hence, it is of great importance to study the techniques of the detection and localization of PD in theory and practice. The detection and localization of PD employing acoustic emission (AE) techniques, as a kind of non-destructive testing, plus due to the advantages of powerful capability of locating and high precision, have been paid more and more attention. The localization algorithm is the key factor to decide the localization accuracy in AE localization of PD. Many kinds of localization algorithms exist for the PD source localization adopting AE techniques including intelligent and non-intelligent algorithms. However, the existed algorithms possess some defects such as the premature convergence phenomenon, poor local optimization ability and unsuitability for the field applications. To overcome the poor local optimization ability and easily caused premature convergence phenomenon of the fundamental genetic algorithm (GA), a new kind of improved GA is proposed, namely the sequence quadratic programming-genetic algorithm (SQP-GA). For the hybrid optimization algorithm, SQP-GA, the sequence quadratic programming (SQP) algorithm which is used as a basic operator is integrated into the fundamental GA, so the local searching ability of the fundamental GA is improved effectively and the premature convergence phenomenon is overcome. Experimental results of the numerical simulations of benchmark functions show that the hybrid optimization algorithm, SQP-GA, is better than the fundamental GA in the convergence speed and optimization precision, and the proposed algorithm in this paper has outstanding optimization effect. At the same time, the presented SQP-GA in the paper is applied to solve the ultrasonic localization problem of PD in transformers, then the ultrasonic localization method of PD in transformers based on the SQP-GA is proposed. And localization results based on the SQP-GA are compared with some algorithms such as the GA, some other intelligent and non-intelligent algorithms. The results of calculating examples both stimulated and spot experiments demonstrate that the localization method based on the SQP-GA can effectively prevent the results from getting trapped into the local optimum values, and the localization method is of great feasibility and very suitable for the field applications, and the precision of localization is enhanced, and the effectiveness of localization is ideal and satisfactory.

  5. Method for hyperspectral imagery exploitation and pixel spectral unmixing

    NASA Technical Reports Server (NTRS)

    Lin, Ching-Fang (Inventor)

    2003-01-01

    An efficiently hybrid approach to exploit hyperspectral imagery and unmix spectral pixels. This hybrid approach uses a genetic algorithm to solve the abundance vector for the first pixel of a hyperspectral image cube. This abundance vector is used as initial state in a robust filter to derive the abundance estimate for the next pixel. By using Kalman filter, the abundance estimate for a pixel can be obtained in one iteration procedure which is much fast than genetic algorithm. The output of the robust filter is fed to genetic algorithm again to derive accurate abundance estimate for the current pixel. The using of robust filter solution as starting point of the genetic algorithm speeds up the evolution of the genetic algorithm. After obtaining the accurate abundance estimate, the procedure goes to next pixel, and uses the output of genetic algorithm as the previous state estimate to derive abundance estimate for this pixel using robust filter. And again use the genetic algorithm to derive accurate abundance estimate efficiently based on the robust filter solution. This iteration continues until pixels in a hyperspectral image cube end.

  6. Fault Detection of Roller-Bearings Using Signal Processing and Optimization Algorithms

    PubMed Central

    Kwak, Dae-Ho; Lee, Dong-Han; Ahn, Jong-Hyo; Koh, Bong-Hwan

    2014-01-01

    This study presents a fault detection of roller bearings through signal processing and optimization techniques. After the occurrence of scratch-type defects on the inner race of bearings, variations of kurtosis values are investigated in terms of two different data processing techniques: minimum entropy deconvolution (MED), and the Teager-Kaiser Energy Operator (TKEO). MED and the TKEO are employed to qualitatively enhance the discrimination of defect-induced repeating peaks on bearing vibration data with measurement noise. Given the perspective of the execution sequence of MED and the TKEO, the study found that the kurtosis sensitivity towards a defect on bearings could be highly improved. Also, the vibration signal from both healthy and damaged bearings is decomposed into multiple intrinsic mode functions (IMFs), through empirical mode decomposition (EMD). The weight vectors of IMFs become design variables for a genetic algorithm (GA). The weights of each IMF can be optimized through the genetic algorithm, to enhance the sensitivity of kurtosis on damaged bearing signals. Experimental results show that the EMD-GA approach successfully improved the resolution of detectability between a roller bearing with defect, and an intact system. PMID:24368701

  7. Development of mathematical models and optimization of the process parameters of laser surface hardened EN25 steel using elitist non-dominated sorting genetic algorithm

    NASA Astrophysics Data System (ADS)

    Vignesh, S.; Dinesh Babu, P.; Surya, G.; Dinesh, S.; Marimuthu, P.

    2018-02-01

    The ultimate goal of all production entities is to select the process parameters that would be of maximum strength, minimum wear and friction. The friction and wear are serious problems in most of the industries which are influenced by the working set of parameters, oxidation characteristics and mechanism involved in formation of wear. The experimental input parameters such as sliding distance, applied load, and temperature are utilized in finding out the optimized solution for achieving the desired output responses such as coefficient of friction, wear rate, and volume loss. The optimization is performed with the help of a novel method, Elitist Non-dominated Sorting Genetic Algorithm (NSGA-II) based on an evolutionary algorithm. The regression equations obtained using Response Surface Methodology (RSM) are used in determining the optimum process parameters. Further, the results achieved through desirability approach in RSM are compared with that of the optimized solution obtained through NSGA-II. The results conclude that proposed evolutionary technique is much effective and faster than the desirability approach.

  8. Model of head-neck joint fast movements in the frontal plane.

    PubMed

    Pedrocchi, A; Ferrigno, G

    2004-06-01

    The objective of this work is to develop a model representing the physiological systems driving fast head movements in frontal plane. All the contributions occurring mechanically in the head movement are considered: damping, stiffness, physiological limit of range of motion, gravitational field, and muscular torques due to voluntary activation as well as to stretch reflex depending on fusal afferences. Model parameters are partly derived from the literature, when possible, whereas undetermined block parameters are determined by optimising the model output, fitting to real kinematics data acquired by a motion capture system in specific experimental set-ups. The optimisation for parameter identification is performed by genetic algorithms. Results show that the model represents very well fast head movements in the whole range of inclination in the frontal plane. Such a model could be proposed as a tool for transforming kinematics data on head movements in 'neural equivalent data', especially for assessing head control disease and properly planning the rehabilitation process. In addition, the use of genetic algorithms seems to fit well the problem of parameter identification, allowing for the use of a very simple experimental set-up and granting model robustness.

  9. Optimization of contrast resolution by genetic algorithm in ultrasound tissue harmonic imaging.

    PubMed

    Ménigot, Sébastien; Girault, Jean-Marc

    2016-09-01

    The development of ultrasound imaging techniques such as pulse inversion has improved tissue harmonic imaging. Nevertheless, no recommendation has been made to date for the design of the waveform transmitted through the medium being explored. Our aim was therefore to find automatically the optimal "imaging" wave which maximized the contrast resolution without a priori information. To overcome assumption regarding the waveform, a genetic algorithm investigated the medium thanks to the transmission of stochastic "explorer" waves. Moreover, these stochastic signals could be constrained by the type of generator available (bipolar or arbitrary). To implement it, we changed the current pulse inversion imaging system by including feedback. Thus the method optimized the contrast resolution by adaptively selecting the samples of the excitation. In simulation, we benchmarked the contrast effectiveness of the best found transmitted stochastic commands and the usual fixed-frequency command. The optimization method converged quickly after around 300 iterations in the same optimal area. These results were confirmed experimentally. In the experimental case, the contrast resolution measured on a radiofrequency line could be improved by 6% with a bipolar generator and it could still increase by 15% with an arbitrary waveform generator. Copyright © 2016 Elsevier B.V. All rights reserved.

  10. A genetic algorithm-based optimization model for pool boiling heat transfer on horizontal rod heaters at isolated bubble regime

    NASA Astrophysics Data System (ADS)

    Alavi Fazel, S. Ali

    2017-09-01

    A new optimized model which can predict the heat transfer in the nucleate boiling at isolated bubble regime is proposed for pool boiling on a horizontal rod heater. This model is developed based on the results of direct observations of the physical boiling phenomena. Boiling heat flux, wall temperature, bubble departing diameter, bubble generation frequency and bubble nucleation site density have been experimentally measured. Water and ethanol have been used as two different boiling fluids. Heating surface was made by several metals and various degrees of roughness. The mentioned model considers various mechanisms such as latent heat transfer due to micro-layer evaporation, transient conduction due to thermal boundary layer reformation, natural convection, heat transfer due to the sliding bubbles and bubble super-heating. The fractional contributions of individual mentioned heat transfer mechanisms have been calculated by genetic algorithm. The results show that at wall temperature difference more that about 3 K, bubble sliding transient conduction, non-sliding transient conduction, micro-layer evaporation, natural convection, radial forced convection and bubble super-heating have higher to lower fractional contributions respectively. The performance of the new optimized model has been verified by comparison of the existing experimental data.

  11. Quantum control via a genetic algorithm of the field ionization pathway of a Rydberg electron

    NASA Astrophysics Data System (ADS)

    Gregoric, Vincent C.; Kang, Xinyue; Liu, Zhimin Cheryl; Rowley, Zoe A.; Carroll, Thomas J.; Noel, Michael W.

    2017-08-01

    Quantum control of the pathway along which a Rydberg electron field ionizes is experimentally and computationally demonstrated. Selective field ionization is typically done with a slowly rising electric field pulse. The (1/n*)4 scaling of the classical ionization threshold leads to a rough mapping between arrival time of the electron signal and principal quantum number of the Rydberg electron. This is complicated by the many avoided level crossings that the electron must traverse on the way to ionization, which in general leads to broadening of the time-resolved field ionization signal. In order to control the ionization pathway, thus directing the signal to the desired arrival time, a perturbing electric field produced by an arbitrary wave-form generator is added to a slowly rising electric field. A genetic algorithm evolves the perturbing field in an effort to achieve the target time-resolved field ionization signal.

  12. Tuning of active vibration controllers for ACTEX by genetic algorithm

    NASA Astrophysics Data System (ADS)

    Kwak, Moon K.; Denoyer, Keith K.

    1999-06-01

    This paper is concerned with the optimal tuning of digitally programmable analog controllers on the ACTEX-1 smart structures flight experiment. The programmable controllers for each channel include a third order Strain Rate Feedback (SRF) controller, a fifth order SRF controller, a second order Positive Position Feedback (PPF) controller, and a fourth order PPF controller. Optimal manual tuning of several control parameters can be a difficult task even though the closed-loop control characteristics of each controller are well known. Hence, the automatic tuning of individual control parameters using Genetic Algorithms is proposed in this paper. The optimal control parameters of each control law are obtained by imposing a constraint on the closed-loop frequency response functions using the ACTEX mathematical model. The tuned control parameters are then uploaded to the ACTEX electronic control electronics and experiments on the active vibration control are carried out in space. The experimental results on ACTEX will be presented.

  13. Genetics-based control of a mimo boiler-turbine plant

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dimeo, R.M.; Lee, K.Y.

    1994-12-31

    A genetic algorithm is used to develop an optimal controller for a non-linear, multi-input/multi-output boiler-turbine plant. The algorithm is used to train a control system for the plant over a wide operating range in an effort to obtain better performance. The results of the genetic algorithm`s controller designed from the linearized plant model at a nominal operating point. Because the genetic algorithm is well-suited to solving traditionally difficult optimization problems it is found that the algorithm is capable of developing the controller based on input/output information only. This controller achieves a performance comparable to the standard linear quadratic regulator.

  14. Improved classification accuracy by feature extraction using genetic algorithms

    NASA Astrophysics Data System (ADS)

    Patriarche, Julia; Manduca, Armando; Erickson, Bradley J.

    2003-05-01

    A feature extraction algorithm has been developed for the purposes of improving classification accuracy. The algorithm uses a genetic algorithm / hill-climber hybrid to generate a set of linearly recombined features, which may be of reduced dimensionality compared with the original set. The genetic algorithm performs the global exploration, and a hill climber explores local neighborhoods. Hybridizing the genetic algorithm with a hill climber improves both the rate of convergence, and the final overall cost function value; it also reduces the sensitivity of the genetic algorithm to parameter selection. The genetic algorithm includes the operators: crossover, mutation, and deletion / reactivation - the last of these effects dimensionality reduction. The feature extractor is supervised, and is capable of deriving a separate feature space for each tissue (which are reintegrated during classification). A non-anatomical digital phantom was developed as a gold standard for testing purposes. In tests with the phantom, and with images of multiple sclerosis patients, classification with feature extractor derived features yielded lower error rates than using standard pulse sequences, and with features derived using principal components analysis. Using the multiple sclerosis patient data, the algorithm resulted in a mean 31% reduction in classification error of pure tissues.

  15. An Extended Spectral-Spatial Classification Approach for Hyperspectral Data

    NASA Astrophysics Data System (ADS)

    Akbari, D.

    2017-11-01

    In this paper an extended classification approach for hyperspectral imagery based on both spectral and spatial information is proposed. The spatial information is obtained by an enhanced marker-based minimum spanning forest (MSF) algorithm. Three different methods of dimension reduction are first used to obtain the subspace of hyperspectral data: (1) unsupervised feature extraction methods including principal component analysis (PCA), independent component analysis (ICA), and minimum noise fraction (MNF); (2) supervised feature extraction including decision boundary feature extraction (DBFE), discriminate analysis feature extraction (DAFE), and nonparametric weighted feature extraction (NWFE); (3) genetic algorithm (GA). The spectral features obtained are then fed into the enhanced marker-based MSF classification algorithm. In the enhanced MSF algorithm, the markers are extracted from the classification maps obtained by both SVM and watershed segmentation algorithm. To evaluate the proposed approach, the Pavia University hyperspectral data is tested. Experimental results show that the proposed approach using GA achieves an approximately 8 % overall accuracy higher than the original MSF-based algorithm.

  16. Study of parameter identification using hybrid neural-genetic algorithm in electro-hydraulic servo system

    NASA Astrophysics Data System (ADS)

    Moon, Byung-Young

    2005-12-01

    The hybrid neural-genetic multi-model parameter estimation algorithm was demonstrated. This method can be applied to structured system identification of electro-hydraulic servo system. This algorithms consist of a recurrent incremental credit assignment(ICRA) neural network and a genetic algorithm. The ICRA neural network evaluates each member of a generation of model and genetic algorithm produces new generation of model. To evaluate the proposed method, electro-hydraulic servo system was designed and manufactured. The experiment was carried out to figure out the hybrid neural-genetic multi-model parameter estimation algorithm. As a result, the dynamic characteristics were obtained such as the parameters(mass, damping coefficient, bulk modulus, spring coefficient), which minimize total square error. The result of this study can be applied to hydraulic systems in industrial fields.

  17. Comparative Approach of MRI-Based Brain Tumor Segmentation and Classification Using Genetic Algorithm.

    PubMed

    Bahadure, Nilesh Bhaskarrao; Ray, Arun Kumar; Thethi, Har Pal

    2018-01-17

    The detection of a brain tumor and its classification from modern imaging modalities is a primary concern, but a time-consuming and tedious work was performed by radiologists or clinical supervisors. The accuracy of detection and classification of tumor stages performed by radiologists is depended on their experience only, so the computer-aided technology is very important to aid with the diagnosis accuracy. In this study, to improve the performance of tumor detection, we investigated comparative approach of different segmentation techniques and selected the best one by comparing their segmentation score. Further, to improve the classification accuracy, the genetic algorithm is employed for the automatic classification of tumor stage. The decision of classification stage is supported by extracting relevant features and area calculation. The experimental results of proposed technique are evaluated and validated for performance and quality analysis on magnetic resonance brain images, based on segmentation score, accuracy, sensitivity, specificity, and dice similarity index coefficient. The experimental results achieved 92.03% accuracy, 91.42% specificity, 92.36% sensitivity, and an average segmentation score between 0.82 and 0.93 demonstrating the effectiveness of the proposed technique for identifying normal and abnormal tissues from brain MR images. The experimental results also obtained an average of 93.79% dice similarity index coefficient, which indicates better overlap between the automated extracted tumor regions with manually extracted tumor region by radiologists.

  18. Firefly Mating Algorithm for Continuous Optimization Problems

    PubMed Central

    Ritthipakdee, Amarita; Premasathian, Nol; Jitkongchuen, Duangjai

    2017-01-01

    This paper proposes a swarm intelligence algorithm, called firefly mating algorithm (FMA), for solving continuous optimization problems. FMA uses genetic algorithm as the core of the algorithm. The main feature of the algorithm is a novel mating pair selection method which is inspired by the following 2 mating behaviors of fireflies in nature: (i) the mutual attraction between males and females causes them to mate and (ii) fireflies of both sexes are of the multiple-mating type, mating with multiple opposite sex partners. A female continues mating until her spermatheca becomes full, and, in the same vein, a male can provide sperms for several females until his sperm reservoir is depleted. This new feature enhances the global convergence capability of the algorithm. The performance of FMA was tested with 20 benchmark functions (sixteen 30-dimensional functions and four 2-dimensional ones) against FA, ALC-PSO, COA, MCPSO, LWGSODE, MPSODDS, DFOA, SHPSOS, LSA, MPDPGA, DE, and GABC algorithms. The experimental results showed that the success rates of our proposed algorithm with these functions were higher than those of other algorithms and the proposed algorithm also required fewer numbers of iterations to reach the global optima. PMID:28808442

  19. Firefly Mating Algorithm for Continuous Optimization Problems.

    PubMed

    Ritthipakdee, Amarita; Thammano, Arit; Premasathian, Nol; Jitkongchuen, Duangjai

    2017-01-01

    This paper proposes a swarm intelligence algorithm, called firefly mating algorithm (FMA), for solving continuous optimization problems. FMA uses genetic algorithm as the core of the algorithm. The main feature of the algorithm is a novel mating pair selection method which is inspired by the following 2 mating behaviors of fireflies in nature: (i) the mutual attraction between males and females causes them to mate and (ii) fireflies of both sexes are of the multiple-mating type, mating with multiple opposite sex partners. A female continues mating until her spermatheca becomes full, and, in the same vein, a male can provide sperms for several females until his sperm reservoir is depleted. This new feature enhances the global convergence capability of the algorithm. The performance of FMA was tested with 20 benchmark functions (sixteen 30-dimensional functions and four 2-dimensional ones) against FA, ALC-PSO, COA, MCPSO, LWGSODE, MPSODDS, DFOA, SHPSOS, LSA, MPDPGA, DE, and GABC algorithms. The experimental results showed that the success rates of our proposed algorithm with these functions were higher than those of other algorithms and the proposed algorithm also required fewer numbers of iterations to reach the global optima.

  20. Comparison of genetic algorithm methods for fuel management optimization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    DeChaine, M.D.; Feltus, M.A.

    1995-12-31

    The CIGARO system was developed for genetic algorithm fuel management optimization. Tests are performed to find the best fuel location swap mutation operator probability and to compare genetic algorithm to a truly random search method. Tests showed the fuel swap probability should be between 0% and 10%, and a 50% definitely hampered the optimization. The genetic algorithm performed significantly better than the random search method, which did not even satisfy the peak normalized power constraint.

  1. Training product unit neural networks with genetic algorithms

    NASA Technical Reports Server (NTRS)

    Janson, D. J.; Frenzel, J. F.; Thelen, D. C.

    1991-01-01

    The training of product neural networks using genetic algorithms is discussed. Two unusual neural network techniques are combined; product units are employed instead of the traditional summing units and genetic algorithms train the network rather than backpropagation. As an example, a neural netork is trained to calculate the optimum width of transistors in a CMOS switch. It is shown how local minima affect the performance of a genetic algorithm, and one method of overcoming this is presented.

  2. New Results in Astrodynamics Using Genetic Algorithms

    NASA Technical Reports Server (NTRS)

    Coverstone-Carroll, V.; Hartmann, J. W.; Williams, S. N.; Mason, W. J.

    1998-01-01

    Generic algorithms have gained popularity as an effective procedure for obtaining solutions to traditionally difficult space mission optimization problems. In this paper, a brief survey of the use of genetic algorithms to solve astrodynamics problems is presented and is followed by new results obtained from applying a Pareto genetic algorithm to the optimization of low-thrust interplanetary spacecraft missions.

  3. JCell--a Java-based framework for inferring regulatory networks from time series data.

    PubMed

    Spieth, C; Supper, J; Streichert, F; Speer, N; Zell, A

    2006-08-15

    JCell is a Java-based application for reconstructing gene regulatory networks from experimental data. The framework provides several algorithms to identify genetic and metabolic dependencies based on experimental data conjoint with mathematical models to describe and simulate regulatory systems. Owing to the modular structure, researchers can easily implement new methods. JCell is a pure Java application with additional scripting capabilities and thus widely usable, e.g. on parallel or cluster computers. The software is freely available for download at http://www-ra.informatik.uni-tuebingen.de/software/JCell.

  4. Clavulanic acid production estimation based on color and structural features of Streptomyces clavuligerus bacteria using self-organizing map and genetic algorithm.

    PubMed

    Nurmohamadi, Maryam; Pourghassem, Hossein

    2014-05-01

    The utilization of antibiotics produced by Clavulanic acid (CA) is an increasing need in medicine and industry. Usually, the CA is created from the fermentation of Streptomycen Clavuligerus (SC) bacteria. Analysis of visual and morphological features of SC bacteria is an appropriate measure to estimate the growth of CA. In this paper, an automatic and fast CA production level estimation algorithm based on visual and structural features of SC bacteria instead of statistical methods and experimental evaluation by microbiologist is proposed. In this algorithm, structural features such as the number of newborn branches, thickness of hyphal and bacterial density and also color features such as acceptance color levels are extracted from the SC bacteria. Moreover, PH and biomass of the medium provided by microbiologists are considered as specified features. The level of CA production is estimated by using a new application of Self-Organizing Map (SOM), and a hybrid model of genetic algorithm with back propagation network (GA-BPN). The proposed algorithm is evaluated on four carbonic resources including malt, starch, wheat flour and glycerol that had used as different mediums of bacterial growth. Then, the obtained results are compared and evaluated with observation of specialist. Finally, the Relative Error (RE) for the SOM and GA-BPN are achieved 14.97% and 16.63%, respectively. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  5. Structural health monitoring feature design by genetic programming

    NASA Astrophysics Data System (ADS)

    Harvey, Dustin Y.; Todd, Michael D.

    2014-09-01

    Structural health monitoring (SHM) systems provide real-time damage and performance information for civil, aerospace, and other high-capital or life-safety critical structures. Conventional data processing involves pre-processing and extraction of low-dimensional features from in situ time series measurements. The features are then input to a statistical pattern recognition algorithm to perform the relevant classification or regression task necessary to facilitate decisions by the SHM system. Traditional design of signal processing and feature extraction algorithms can be an expensive and time-consuming process requiring extensive system knowledge and domain expertise. Genetic programming, a heuristic program search method from evolutionary computation, was recently adapted by the authors to perform automated, data-driven design of signal processing and feature extraction algorithms for statistical pattern recognition applications. The proposed method, called Autofead, is particularly suitable to handle the challenges inherent in algorithm design for SHM problems where the manifestation of damage in structural response measurements is often unclear or unknown. Autofead mines a training database of response measurements to discover information-rich features specific to the problem at hand. This study provides experimental validation on three SHM applications including ultrasonic damage detection, bearing damage classification for rotating machinery, and vibration-based structural health monitoring. Performance comparisons with common feature choices for each problem area are provided demonstrating the versatility of Autofead to produce significant algorithm improvements on a wide range of problems.

  6. Nonlinear inversion of potential-field data using a hybrid-encoding genetic algorithm

    USGS Publications Warehouse

    Chen, C.; Xia, J.; Liu, J.; Feng, G.

    2006-01-01

    Using a genetic algorithm to solve an inverse problem of complex nonlinear geophysical equations is advantageous because it does not require computer gradients of models or "good" initial models. The multi-point search of a genetic algorithm makes it easier to find the globally optimal solution while avoiding falling into a local extremum. As is the case in other optimization approaches, the search efficiency for a genetic algorithm is vital in finding desired solutions successfully in a multi-dimensional model space. A binary-encoding genetic algorithm is hardly ever used to resolve an optimization problem such as a simple geophysical inversion with only three unknowns. The encoding mechanism, genetic operators, and population size of the genetic algorithm greatly affect search processes in the evolution. It is clear that improved operators and proper population size promote the convergence. Nevertheless, not all genetic operations perform perfectly while searching under either a uniform binary or a decimal encoding system. With the binary encoding mechanism, the crossover scheme may produce more new individuals than with the decimal encoding. On the other hand, the mutation scheme in a decimal encoding system will create new genes larger in scope than those in the binary encoding. This paper discusses approaches of exploiting the search potential of genetic operations in the two encoding systems and presents an approach with a hybrid-encoding mechanism, multi-point crossover, and dynamic population size for geophysical inversion. We present a method that is based on the routine in which the mutation operation is conducted in the decimal code and multi-point crossover operation in the binary code. The mix-encoding algorithm is called the hybrid-encoding genetic algorithm (HEGA). HEGA provides better genes with a higher probability by a mutation operator and improves genetic algorithms in resolving complicated geophysical inverse problems. Another significant result is that final solution is determined by the average model derived from multiple trials instead of one computation due to the randomness in a genetic algorithm procedure. These advantages were demonstrated by synthetic and real-world examples of inversion of potential-field data. ?? 2005 Elsevier Ltd. All rights reserved.

  7. Simulated maximum likelihood method for estimating kinetic rates in gene expression.

    PubMed

    Tian, Tianhai; Xu, Songlin; Gao, Junbin; Burrage, Kevin

    2007-01-01

    Kinetic rate in gene expression is a key measurement of the stability of gene products and gives important information for the reconstruction of genetic regulatory networks. Recent developments in experimental technologies have made it possible to measure the numbers of transcripts and protein molecules in single cells. Although estimation methods based on deterministic models have been proposed aimed at evaluating kinetic rates from experimental observations, these methods cannot tackle noise in gene expression that may arise from discrete processes of gene expression, small numbers of mRNA transcript, fluctuations in the activity of transcriptional factors and variability in the experimental environment. In this paper, we develop effective methods for estimating kinetic rates in genetic regulatory networks. The simulated maximum likelihood method is used to evaluate parameters in stochastic models described by either stochastic differential equations or discrete biochemical reactions. Different types of non-parametric density functions are used to measure the transitional probability of experimental observations. For stochastic models described by biochemical reactions, we propose to use the simulated frequency distribution to evaluate the transitional density based on the discrete nature of stochastic simulations. The genetic optimization algorithm is used as an efficient tool to search for optimal reaction rates. Numerical results indicate that the proposed methods can give robust estimations of kinetic rates with good accuracy.

  8. Aerodynamic Optimization of a Supersonic Bending Body Projectile by a Vector-Evaluated Genetic Algorithm

    DTIC Science & Technology

    2016-12-01

    Evaluated Genetic Algorithm prepared by Justin L Paul Academy of Applied Science 24 Warren Street Concord, NH 03301 under contract W911SR...Supersonic Bending Body Projectile by a Vector-Evaluated Genetic Algorithm prepared by Justin L Paul Academy of Applied Science 24 Warren Street... Genetic Algorithm 5a. CONTRACT NUMBER W199SR-15-2-001 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Justin L Paul 5d. PROJECT

  9. A three-way parallel ICA approach to analyze links among genetics, brain structure and brain function.

    PubMed

    Vergara, Victor M; Ulloa, Alvaro; Calhoun, Vince D; Boutte, David; Chen, Jiayu; Liu, Jingyu

    2014-09-01

    Multi-modal data analysis techniques, such as the Parallel Independent Component Analysis (pICA), are essential in neuroscience, medical imaging and genetic studies. The pICA algorithm allows the simultaneous decomposition of up to two data modalities achieving better performance than separate ICA decompositions and enabling the discovery of links between modalities. However, advances in data acquisition techniques facilitate the collection of more than two data modalities from each subject. Examples of commonly measured modalities include genetic information, structural magnetic resonance imaging (MRI) and functional MRI. In order to take full advantage of the available data, this work extends the pICA approach to incorporate three modalities in one comprehensive analysis. Simulations demonstrate the three-way pICA performance in identifying pairwise links between modalities and estimating independent components which more closely resemble the true sources than components found by pICA or separate ICA analyses. In addition, the three-way pICA algorithm is applied to real experimental data obtained from a study that investigate genetic effects on alcohol dependence. Considered data modalities include functional MRI (contrast images during alcohol exposure paradigm), gray matter concentration images from structural MRI and genetic single nucleotide polymorphism (SNP). The three-way pICA approach identified links between a SNP component (pointing to brain function and mental disorder associated genes, including BDNF, GRIN2B and NRG1), a functional component related to increased activation in the precuneus area, and a gray matter component comprising part of the default mode network and the caudate. Although such findings need further verification, the simulation and in-vivo results validate the three-way pICA algorithm presented here as a useful tool in biomedical data fusion applications. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. Nonlinear dynamics optimization with particle swarm and genetic algorithms for SPEAR3 emittance upgrade

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huang, Xiaobiao; Safranek, James

    2014-09-01

    Nonlinear dynamics optimization is carried out for a low emittance upgrade lattice of SPEAR3 in order to improve its dynamic aperture and Touschek lifetime. Two multi-objective optimization algorithms, a genetic algorithm and a particle swarm algorithm, are used for this study. The performance of the two algorithms are compared. The result shows that the particle swarm algorithm converges significantly faster to similar or better solutions than the genetic algorithm and it does not require seeding of good solutions in the initial population. These advantages of the particle swarm algorithm may make it more suitable for many accelerator optimization applications.

  11. Genetic Algorithm for Initial Orbit Determination with Too Short Arc (Continued)

    NASA Astrophysics Data System (ADS)

    Li, X. R.; Wang, X.

    2016-03-01

    When using the genetic algorithm to solve the problem of too-short-arc (TSA) determination, due to the difference of computing processes between the genetic algorithm and classical method, the methods for outliers editing are no longer applicable. In the genetic algorithm, the robust estimation is acquired by means of using different loss functions in the fitness function, then the outlier problem of TSAs is solved. Compared with the classical method, the application of loss functions in the genetic algorithm is greatly simplified. Through the comparison of results of different loss functions, it is clear that the methods of least median square and least trimmed square can greatly improve the robustness of TSAs, and have a high breakdown point.

  12. Bio-Inspired Genetic Algorithms with Formalized Crossover Operators for Robotic Applications.

    PubMed

    Zhang, Jie; Kang, Man; Li, Xiaojuan; Liu, Geng-Yang

    2017-01-01

    Genetic algorithms are widely adopted to solve optimization problems in robotic applications. In such safety-critical systems, it is vitally important to formally prove the correctness when genetic algorithms are applied. This paper focuses on formal modeling of crossover operations that are one of most important operations in genetic algorithms. Specially, we for the first time formalize crossover operations with higher-order logic based on HOL4 that is easy to be deployed with its user-friendly programing environment. With correctness-guaranteed formalized crossover operations, we can safely apply them in robotic applications. We implement our technique to solve a path planning problem using a genetic algorithm with our formalized crossover operations, and the results show the effectiveness of our technique.

  13. Stochastic model search with binary outcomes for genome-wide association studies.

    PubMed

    Russu, Alberto; Malovini, Alberto; Puca, Annibale A; Bellazzi, Riccardo

    2012-06-01

    The spread of case-control genome-wide association studies (GWASs) has stimulated the development of new variable selection methods and predictive models. We introduce a novel Bayesian model search algorithm, Binary Outcome Stochastic Search (BOSS), which addresses the model selection problem when the number of predictors far exceeds the number of binary responses. Our method is based on a latent variable model that links the observed outcomes to the underlying genetic variables. A Markov Chain Monte Carlo approach is used for model search and to evaluate the posterior probability of each predictor. BOSS is compared with three established methods (stepwise regression, logistic lasso, and elastic net) in a simulated benchmark. Two real case studies are also investigated: a GWAS on the genetic bases of longevity, and the type 2 diabetes study from the Wellcome Trust Case Control Consortium. Simulations show that BOSS achieves higher precisions than the reference methods while preserving good recall rates. In both experimental studies, BOSS successfully detects genetic polymorphisms previously reported to be associated with the analyzed phenotypes. BOSS outperforms the other methods in terms of F-measure on simulated data. In the two real studies, BOSS successfully detects biologically relevant features, some of which are missed by univariate analysis and the three reference techniques. The proposed algorithm is an advance in the methodology for model selection with a large number of features. Our simulated and experimental results showed that BOSS proves effective in detecting relevant markers while providing a parsimonious model.

  14. 4D-Qsar Study of Some Pyrazole Pyridine Carboxylic Acid Derivatives by Electron Conformational-Genetic Algorithm Method.

    PubMed

    Tuzun, Burak; Yavuz, Sevtap Caglar; Sabanci, Nazmiye; Saripinar, Emin

    2018-05-13

    In the present work, pharmacophore identification and biological activity prediction for 86 pyrazole pyridine carboxylic acid derivatives were made using the electron conformational genetic algorithm approach which was introduced as a 4D-QSAR analysis by us in recent years. In the light of the data obtained from quantum chemical calculations at HF/6-311 G** level, the electron conformational matrices of congruity (ECMC) were constructed by EMRE software. Comparing the matrices, electron conformational submatrix of activity (ECSA, Pha) was revealed that are common for these compounds within a minimum tolerance. A parameter pool was generated considering the obtained pharmacophore. To determine the theoretical biological activity of molecules and identify the best subset of variables affecting bioactivities, we used the nonlinear least square regression method and genetic algorithm. The results obtained in this study are in good agreement with the experimental data presented in the literature. The model for training and test sets attained by the optimum 12 parameters gave highly satisfactory results with R2training= 0.889, q2=0.839 and SEtraining=0.066, q2ext1 = 0.770, q2ext2 = 0.750, q2ext3=0.824, ccctr = 0.941, ccctest = 0.869 and cccall = 0.927. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  15. Multi-objective parametric optimization of Inertance type pulse tube refrigerator using response surface methodology and non-dominated sorting genetic algorithm

    NASA Astrophysics Data System (ADS)

    Rout, Sachindra K.; Choudhury, Balaji K.; Sahoo, Ranjit K.; Sarangi, Sunil K.

    2014-07-01

    The modeling and optimization of a Pulse Tube Refrigerator is a complicated task, due to its complexity of geometry and nature. The aim of the present work is to optimize the dimensions of pulse tube and regenerator for an Inertance-Type Pulse Tube Refrigerator (ITPTR) by using Response Surface Methodology (RSM) and Non-Sorted Genetic Algorithm II (NSGA II). The Box-Behnken design of the response surface methodology is used in an experimental matrix, with four factors and two levels. The diameter and length of the pulse tube and regenerator are chosen as the design variables where the rest of the dimensions and operating conditions of the ITPTR are constant. The required output responses are the cold head temperature (Tcold) and compressor input power (Wcomp). Computational fluid dynamics (CFD) have been used to model and solve the ITPTR. The CFD results agreed well with those of the previously published paper. Also using the results from the 1-D simulation, RSM is conducted to analyse the effect of the independent variables on the responses. To check the accuracy of the model, the analysis of variance (ANOVA) method has been used. Based on the proposed mathematical RSM models a multi-objective optimization study, using the Non-sorted genetic algorithm II (NSGA-II) has been performed to optimize the responses.

  16. A Test of Genetic Algorithms in Relevance Feedback.

    ERIC Educational Resources Information Center

    Lopez-Pujalte, Cristina; Guerrero Bote, Vicente P.; Moya Anegon, Felix de

    2002-01-01

    Discussion of information retrieval, query optimization techniques, and relevance feedback focuses on genetic algorithms, which are derived from artificial intelligence techniques. Describes an evaluation of different genetic algorithms using a residual collection method and compares results with the Ide dec-hi method (Salton and Buckley, 1990…

  17. Transonic Wing Shape Optimization Using a Genetic Algorithm

    NASA Technical Reports Server (NTRS)

    Holst, Terry L.; Pulliam, Thomas H.; Kwak, Dochan (Technical Monitor)

    2002-01-01

    A method for aerodynamic shape optimization based on a genetic algorithm approach is demonstrated. The algorithm is coupled with a transonic full potential flow solver and is used to optimize the flow about transonic wings including multi-objective solutions that lead to the generation of pareto fronts. The results indicate that the genetic algorithm is easy to implement, flexible in application and extremely reliable.

  18. Portfolio optimization by using linear programing models based on genetic algorithm

    NASA Astrophysics Data System (ADS)

    Sukono; Hidayat, Y.; Lesmana, E.; Putra, A. S.; Napitupulu, H.; Supian, S.

    2018-01-01

    In this paper, we discussed the investment portfolio optimization using linear programming model based on genetic algorithms. It is assumed that the portfolio risk is measured by absolute standard deviation, and each investor has a risk tolerance on the investment portfolio. To complete the investment portfolio optimization problem, the issue is arranged into a linear programming model. Furthermore, determination of the optimum solution for linear programming is done by using a genetic algorithm. As a numerical illustration, we analyze some of the stocks traded on the capital market in Indonesia. Based on the analysis, it is shown that the portfolio optimization performed by genetic algorithm approach produces more optimal efficient portfolio, compared to the portfolio optimization performed by a linear programming algorithm approach. Therefore, genetic algorithms can be considered as an alternative on determining the investment portfolio optimization, particularly using linear programming models.

  19. An improved genetic algorithm and its application in the TSP problem

    NASA Astrophysics Data System (ADS)

    Li, Zheng; Qin, Jinlei

    2011-12-01

    Concept and research actuality of genetic algorithm are introduced in detail in the paper. Under this condition, the simple genetic algorithm and an improved algorithm are described and applied in an example of TSP problem, where the advantage of genetic algorithm is adequately shown in solving the NP-hard problem. In addition, based on partial matching crossover operator, the crossover operator method is improved into extended crossover operator in order to advance the efficiency when solving the TSP. In the extended crossover method, crossover operator can be performed between random positions of two random individuals, which will not be restricted by the position of chromosome. Finally, the nine-city TSP is solved using the improved genetic algorithm with extended crossover method, the efficiency of whose solution process is much higher, besides, the solving speed of the optimal solution is much faster.

  20. Solving TSP problem with improved genetic algorithm

    NASA Astrophysics Data System (ADS)

    Fu, Chunhua; Zhang, Lijun; Wang, Xiaojing; Qiao, Liying

    2018-05-01

    The TSP is a typical NP problem. The optimization of vehicle routing problem (VRP) and city pipeline optimization can use TSP to solve; therefore it is very important to the optimization for solving TSP problem. The genetic algorithm (GA) is one of ideal methods in solving it. The standard genetic algorithm has some limitations. Improving the selection operator of genetic algorithm, and importing elite retention strategy can ensure the select operation of quality, In mutation operation, using the adaptive algorithm selection can improve the quality of search results and variation, after the chromosome evolved one-way evolution reverse operation is added which can make the offspring inherit gene of parental quality improvement opportunities, and improve the ability of searching the optimal solution algorithm.

  1. Genetic algorithm based fuzzy control of spacecraft autonomous rendezvous

    NASA Technical Reports Server (NTRS)

    Karr, C. L.; Freeman, L. M.; Meredith, D. L.

    1990-01-01

    The U.S. Bureau of Mines is currently investigating ways to combine the control capabilities of fuzzy logic with the learning capabilities of genetic algorithms. Fuzzy logic allows for the uncertainty inherent in most control problems to be incorporated into conventional expert systems. Although fuzzy logic based expert systems have been used successfully for controlling a number of physical systems, the selection of acceptable fuzzy membership functions has generally been a subjective decision. High performance fuzzy membership functions for a fuzzy logic controller that manipulates a mathematical model simulating the autonomous rendezvous of spacecraft are learned using a genetic algorithm, a search technique based on the mechanics of natural genetics. The membership functions learned by the genetic algorithm provide for a more efficient fuzzy logic controller than membership functions selected by the authors for the rendezvous problem. Thus, genetic algorithms are potentially an effective and structured approach for learning fuzzy membership functions.

  2. A "Hands on" Strategy for Teaching Genetic Algorithms to Undergraduates

    ERIC Educational Resources Information Center

    Venables, Anne; Tan, Grace

    2007-01-01

    Genetic algorithms (GAs) are a problem solving strategy that uses stochastic search. Since their introduction (Holland, 1975), GAs have proven to be particularly useful for solving problems that are "intractable" using classical methods. The language of genetic algorithms (GAs) is heavily laced with biological metaphors from evolutionary…

  3. CamOptimus: a tool for exploiting complex adaptive evolution to optimize experiments and processes in biotechnology.

    PubMed

    Cankorur-Cetinkaya, Ayca; Dias, Joao M L; Kludas, Jana; Slater, Nigel K H; Rousu, Juho; Oliver, Stephen G; Dikicioglu, Duygu

    2017-06-01

    Multiple interacting factors affect the performance of engineered biological systems in synthetic biology projects. The complexity of these biological systems means that experimental design should often be treated as a multiparametric optimization problem. However, the available methodologies are either impractical, due to a combinatorial explosion in the number of experiments to be performed, or are inaccessible to most experimentalists due to the lack of publicly available, user-friendly software. Although evolutionary algorithms may be employed as alternative approaches to optimize experimental design, the lack of simple-to-use software again restricts their use to specialist practitioners. In addition, the lack of subsidiary approaches to further investigate critical factors and their interactions prevents the full analysis and exploitation of the biotechnological system. We have addressed these problems and, here, provide a simple-to-use and freely available graphical user interface to empower a broad range of experimental biologists to employ complex evolutionary algorithms to optimize their experimental designs. Our approach exploits a Genetic Algorithm to discover the subspace containing the optimal combination of parameters, and Symbolic Regression to construct a model to evaluate the sensitivity of the experiment to each parameter under investigation. We demonstrate the utility of this method using an example in which the culture conditions for the microbial production of a bioactive human protein are optimized. CamOptimus is available through: (https://doi.org/10.17863/CAM.10257).

  4. The potential of genetic algorithms for conceptual design of rotor systems

    NASA Technical Reports Server (NTRS)

    Crossley, William A.; Wells, Valana L.; Laananen, David H.

    1993-01-01

    The capabilities of genetic algorithms as a non-calculus based, global search method make them potentially useful in the conceptual design of rotor systems. Coupling reasonably simple analysis tools to the genetic algorithm was accomplished, and the resulting program was used to generate designs for rotor systems to match requirements similar to those of both an existing helicopter and a proposed helicopter design. This provides a comparison with the existing design and also provides insight into the potential of genetic algorithms in design of new rotors.

  5. Genetic Algorithm for Initial Orbit Determination with Too Short Arc (Continued)

    NASA Astrophysics Data System (ADS)

    Li, Xin-ran; Wang, Xin

    2017-04-01

    When the genetic algorithm is used to solve the problem of too short-arc (TSA) orbit determination, due to the difference of computing process between the genetic algorithm and the classical method, the original method for outlier deletion is no longer applicable. In the genetic algorithm, the robust estimation is realized by introducing different loss functions for the fitness function, then the outlier problem of the TSA orbit determination is solved. Compared with the classical method, the genetic algorithm is greatly simplified by introducing in different loss functions. Through the comparison on the calculations of multiple loss functions, it is found that the least median square (LMS) estimation and least trimmed square (LTS) estimation can greatly improve the robustness of the TSA orbit determination, and have a high breakdown point.

  6. A Genetic Algorithm Tool (splicer) for Complex Scheduling Problems and the Space Station Freedom Resupply Problem

    NASA Technical Reports Server (NTRS)

    Wang, Lui; Valenzuela-Rendon, Manuel

    1993-01-01

    The Space Station Freedom will require the supply of items in a regular fashion. A schedule for the delivery of these items is not easy to design due to the large span of time involved and the possibility of cancellations and changes in shuttle flights. This paper presents the basic concepts of a genetic algorithm model, and also presents the results of an effort to apply genetic algorithms to the design of propellant resupply schedules. As part of this effort, a simple simulator and an encoding by which a genetic algorithm can find near optimal schedules have been developed. Additionally, this paper proposes ways in which robust schedules, i.e., schedules that can tolerate small changes, can be found using genetic algorithms.

  7. Simulation Modeling to Compare High-Throughput, Low-Iteration Optimization Strategies for Metabolic Engineering

    PubMed Central

    Heinsch, Stephen C.; Das, Siba R.; Smanski, Michael J.

    2018-01-01

    Increasing the final titer of a multi-gene metabolic pathway can be viewed as a multivariate optimization problem. While numerous multivariate optimization algorithms exist, few are specifically designed to accommodate the constraints posed by genetic engineering workflows. We present a strategy for optimizing expression levels across an arbitrary number of genes that requires few design-build-test iterations. We compare the performance of several optimization algorithms on a series of simulated expression landscapes. We show that optimal experimental design parameters depend on the degree of landscape ruggedness. This work provides a theoretical framework for designing and executing numerical optimization on multi-gene systems. PMID:29535690

  8. Micromagnetic measurement for characterization of ferromagnetic materials' microstructural properties

    NASA Astrophysics Data System (ADS)

    Zhang, Shuo; Shi, Xiaodong; Udpa, Lalita; Deng, Yiming

    2018-05-01

    Magnetic Barkhausen noise (MBN) is measured in low carbon steels and the relationship between carbon content and parameter extracted from MBN signal has been investigated. The parameter is extracted experimentally by fitting the original profiles with two Gaussian curves. The gap between two peaks (ΔG) of fitted Gaussian curves shows a better linear relationship with carbon contents of samples in the experiment. The result has been validated with simulation by Monte Carlo method. To ensure the sensitivity of measurement, advanced multi-objective optimization algorithm Non-dominant sorting genetic algorithm III (NSGA III) has been used to fulfill the optimization of the magnetic core of sensor.

  9. Forecasting impact injuries of unrestrained occupants in railway vehicle passenger compartments.

    PubMed

    Xie, Suchao; Zhou, Hui

    2014-01-01

    In order to predict the injury parameters of the occupants corresponding to different experimental parameters and to determine impact injury indices conveniently and efficiently, a model forecasting occupant impact injury was established in this work. The work was based on finite experimental observation values obtained by numerical simulation. First, the various factors influencing the impact injuries caused by the interaction between unrestrained occupants and the compartment's internal structures were collated and the most vulnerable regions of the occupant's body were analyzed. Then, the forecast model was set up based on a genetic algorithm-back propagation (GA-BP) hybrid algorithm, which unified the individual characteristics of the back propagation-artificial neural network (BP-ANN) model and the genetic algorithm (GA). The model was well suited to studies of occupant impact injuries and allowed multiple-parameter forecasts of the occupant impact injuries to be realized assuming values for various influencing factors. Finally, the forecast results for three types of secondary collision were analyzed using forecasting accuracy evaluation methods. All of the results showed the ideal accuracy of the forecast model. When an occupant faced a table, the relative errors between the predicted and experimental values of the respective injury parameters were kept within ± 6.0 percent and the average relative error (ARE) values did not exceed 3.0 percent. When an occupant faced a seat, the relative errors between the predicted and experimental values of the respective injury parameters were kept within ± 5.2 percent and the ARE values did not exceed 3.1 percent. When the occupant faced another occupant, the relative errors between the predicted and experimental values of the respective injury parameters were kept within ± 6.3 percent and the ARE values did not exceed 3.8 percent. The injury forecast model established in this article reduced repeat experiment times and improved the design efficiency of the internal compartment's structure parameters, and it provided a new way for assessing the safety performance of the interior structural parameters in existing, and newly designed, railway vehicle compartments.

  10. Structure and weights optimisation of a modified Elman network emotion classifier using hybrid computational intelligence algorithms: a comparative study

    NASA Astrophysics Data System (ADS)

    Sheikhan, Mansour; Abbasnezhad Arabi, Mahdi; Gharavian, Davood

    2015-10-01

    Artificial neural networks are efficient models in pattern recognition applications, but their performance is dependent on employing suitable structure and connection weights. This study used a hybrid method for obtaining the optimal weight set and architecture of a recurrent neural emotion classifier based on gravitational search algorithm (GSA) and its binary version (BGSA), respectively. By considering the features of speech signal that were related to prosody, voice quality, and spectrum, a rich feature set was constructed. To select more efficient features, a fast feature selection method was employed. The performance of the proposed hybrid GSA-BGSA method was compared with similar hybrid methods based on particle swarm optimisation (PSO) algorithm and its binary version, PSO and discrete firefly algorithm, and hybrid of error back-propagation and genetic algorithm that were used for optimisation. Experimental tests on Berlin emotional database demonstrated the superior performance of the proposed method using a lighter network structure.

  11. An Improved Heuristic Method for Subgraph Isomorphism Problem

    NASA Astrophysics Data System (ADS)

    Xiang, Yingzhuo; Han, Jiesi; Xu, Haijiang; Guo, Xin

    2017-09-01

    This paper focus on the subgraph isomorphism (SI) problem. We present an improved genetic algorithm, a heuristic method to search the optimal solution. The contribution of this paper is that we design a dedicated crossover algorithm and a new fitness function to measure the evolution process. Experiments show our improved genetic algorithm performs better than other heuristic methods. For a large graph, such as a subgraph of 40 nodes, our algorithm outperforms the traditional tree search algorithms. We find that the performance of our improved genetic algorithm does not decrease as the number of nodes in prototype graphs.

  12. Design of Energy Storage Management System Based on FPGA in Micro-Grid

    NASA Astrophysics Data System (ADS)

    Liang, Yafeng; Wang, Yanping; Han, Dexiao

    2018-01-01

    Energy storage system is the core to maintain the stable operation of smart micro-grid. Aiming at the existing problems of the energy storage management system in the micro-grid such as Low fault tolerance, easy to cause fluctuations in micro-grid, a new intelligent battery management system based on field programmable gate array is proposed : taking advantage of FPGA to combine the battery management system with the intelligent micro-grid control strategy. Finally, aiming at the problem that during estimation of battery charge State by neural network, initialization of weights and thresholds are not accurate leading to large errors in prediction results, the genetic algorithm is proposed to optimize the neural network method, and the experimental simulation is carried out. The experimental results show that the algorithm has high precision and provides guarantee for the stable operation of micro-grid.

  13. Genetic algorithms for adaptive real-time control in space systems

    NASA Technical Reports Server (NTRS)

    Vanderzijp, J.; Choudry, A.

    1988-01-01

    Genetic Algorithms that are used for learning as one way to control the combinational explosion associated with the generation of new rules are discussed. The Genetic Algorithm approach tends to work best when it can be applied to a domain independent knowledge representation. Applications to real time control in space systems are discussed.

  14. Cognitive Nonlinear Radar

    DTIC Science & Technology

    2013-01-01

    intelligently selecting waveform parameters using adaptive algorithms. The adaptive algorithms optimize the waveform parameters based on (1) the EM...the environment. 15. SUBJECT TERMS cognitive radar, adaptive sensing, spectrum sensing, multi-objective optimization, genetic algorithms, machine...detection and classification block diagram. .........................................................6 Figure 5. Genetic algorithm block diagram

  15. Optimising the production of succinate and lactate in Escherichia coli using a hybrid of artificial bee colony algorithm and minimisation of metabolic adjustment.

    PubMed

    Tang, Phooi Wah; Choon, Yee Wen; Mohamad, Mohd Saberi; Deris, Safaai; Napis, Suhaimi

    2015-03-01

    Metabolic engineering is a research field that focuses on the design of models for metabolism, and uses computational procedures to suggest genetic manipulation. It aims to improve the yield of particular chemical or biochemical products. Several traditional metabolic engineering methods are commonly used to increase the production of a desired target, but the products are always far below their theoretical maximums. Using numeral optimisation algorithms to identify gene knockouts may stall at a local minimum in a multivariable function. This paper proposes a hybrid of the artificial bee colony (ABC) algorithm and the minimisation of metabolic adjustment (MOMA) to predict an optimal set of solutions in order to optimise the production rate of succinate and lactate. The dataset used in this work was from the iJO1366 Escherichia coli metabolic network. The experimental results include the production rate, growth rate and a list of knockout genes. From the comparative analysis, ABCMOMA produced better results compared to previous works, showing potential for solving genetic engineering problems. Copyright © 2014 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  16. Prediction of microRNA target genes using an efficient genetic algorithm-based decision tree.

    PubMed

    Rabiee-Ghahfarrokhi, Behzad; Rafiei, Fariba; Niknafs, Ali Akbar; Zamani, Behzad

    2015-01-01

    MicroRNAs (miRNAs) are small, non-coding RNA molecules that regulate gene expression in almost all plants and animals. They play an important role in key processes, such as proliferation, apoptosis, and pathogen-host interactions. Nevertheless, the mechanisms by which miRNAs act are not fully understood. The first step toward unraveling the function of a particular miRNA is the identification of its direct targets. This step has shown to be quite challenging in animals primarily because of incomplete complementarities between miRNA and target mRNAs. In recent years, the use of machine-learning techniques has greatly increased the prediction of miRNA targets, avoiding the need for costly and time-consuming experiments to achieve miRNA targets experimentally. Among the most important machine-learning algorithms are decision trees, which classify data based on extracted rules. In the present work, we used a genetic algorithm in combination with C4.5 decision tree for prediction of miRNA targets. We applied our proposed method to a validated human datasets. We nearly achieved 93.9% accuracy of classification, which could be related to the selection of best rules.

  17. High density DNA microarrays: algorithms and biomedical applications.

    PubMed

    Liu, Wei-Min

    2004-08-01

    DNA microarrays are devices capable of detecting the identity and abundance of numerous DNA or RNA segments in samples. They are used for analyzing gene expressions, identifying genetic markers and detecting mutations on a genomic scale. The fundamental chemical mechanism of DNA microarrays is the hybridization between probes and targets due to the hydrogen bonds of nucleotide base pairing. Since the cross hybridization is inevitable, and probes or targets may form undesirable secondary or tertiary structures, the microarray data contain noise and depend on experimental conditions. It is crucial to apply proper statistical algorithms to obtain useful signals from noisy data. After we obtained the signals of a large amount of probes, we need to derive the biomedical information such as the existence of a transcript in a cell, the difference of expression levels of a gene in multiple samples, and the type of a genetic marker. Furthermore, after the expression levels of thousands of genes or the genotypes of thousands of single nucleotide polymorphisms are determined, it is usually important to find a small number of genes or markers that are related to a disease, individual reactions to drugs, or other phenotypes. All these applications need careful data analyses and reliable algorithms.

  18. Prediction of microRNA target genes using an efficient genetic algorithm-based decision tree

    PubMed Central

    Rabiee-Ghahfarrokhi, Behzad; Rafiei, Fariba; Niknafs, Ali Akbar; Zamani, Behzad

    2015-01-01

    MicroRNAs (miRNAs) are small, non-coding RNA molecules that regulate gene expression in almost all plants and animals. They play an important role in key processes, such as proliferation, apoptosis, and pathogen–host interactions. Nevertheless, the mechanisms by which miRNAs act are not fully understood. The first step toward unraveling the function of a particular miRNA is the identification of its direct targets. This step has shown to be quite challenging in animals primarily because of incomplete complementarities between miRNA and target mRNAs. In recent years, the use of machine-learning techniques has greatly increased the prediction of miRNA targets, avoiding the need for costly and time-consuming experiments to achieve miRNA targets experimentally. Among the most important machine-learning algorithms are decision trees, which classify data based on extracted rules. In the present work, we used a genetic algorithm in combination with C4.5 decision tree for prediction of miRNA targets. We applied our proposed method to a validated human datasets. We nearly achieved 93.9% accuracy of classification, which could be related to the selection of best rules. PMID:26649272

  19. Global optimization and reflectivity data fitting for x-ray multilayer mirrors by means of genetic algorithms

    NASA Astrophysics Data System (ADS)

    Sanchez del Rio, Manuel; Pareschi, Giovanni

    2001-01-01

    The x-ray reflectivity of a multilayer is a non-linear function of many parameters (materials, layer thicknesses, densities, roughness). Non-linear fitting of experimental data with simulations requires to use initial values sufficiently close to the optimum value. This is a difficult task when the space topology of the variables is highly structured, as in our case. The application of global optimization methods to fit multilayer reflectivity data is presented. Genetic algorithms are stochastic methods based on the model of natural evolution: the improvement of a population along successive generations. A complete set of initial parameters constitutes an individual. The population is a collection of individuals. Each generation is built from the parent generation by applying some operators (e.g. selection, crossover, mutation) on the members of the parent generation. The pressure of selection drives the population to include 'good' individuals. For large number of generations, the best individuals will approximate the optimum parameters. Some results on fitting experimental hard x-ray reflectivity data for Ni/C multilayers recorded at the ESRF BM5 are presented. This method could be also applied to the help in the design of multilayers optimized for a target application, like for an astronomical grazing-incidence hard X-ray telescopes.

  20. Genetic algorithm for the optimization of features and neural networks in ECG signals classification

    NASA Astrophysics Data System (ADS)

    Li, Hongqiang; Yuan, Danyang; Ma, Xiangdong; Cui, Dianyin; Cao, Lu

    2017-01-01

    Feature extraction and classification of electrocardiogram (ECG) signals are necessary for the automatic diagnosis of cardiac diseases. In this study, a novel method based on genetic algorithm-back propagation neural network (GA-BPNN) for classifying ECG signals with feature extraction using wavelet packet decomposition (WPD) is proposed. WPD combined with the statistical method is utilized to extract the effective features of ECG signals. The statistical features of the wavelet packet coefficients are calculated as the feature sets. GA is employed to decrease the dimensions of the feature sets and to optimize the weights and biases of the back propagation neural network (BPNN). Thereafter, the optimized BPNN classifier is applied to classify six types of ECG signals. In addition, an experimental platform is constructed for ECG signal acquisition to supply the ECG data for verifying the effectiveness of the proposed method. The GA-BPNN method with the MIT-BIH arrhythmia database achieved a dimension reduction of nearly 50% and produced good classification results with an accuracy of 97.78%. The experimental results based on the established acquisition platform indicated that the GA-BPNN method achieved a high classification accuracy of 99.33% and could be efficiently applied in the automatic identification of cardiac arrhythmias.

  1. Feedback quantum control of molecular electronic population transfer

    NASA Astrophysics Data System (ADS)

    Bardeen, Christopher J.; Yakovlev, Vladislav V.; Wilson, Kent R.; Carpenter, Scott D.; Weber, Peter M.; Warren, Warren S.

    1997-11-01

    Feedback quantum control, where the sample `teaches' a computer-controlled arbitrary lightform generator to find the optimal light field, is experimentally demonstrated for a molecular system. Femtosecond pulses tailored by a computer-controlled acousto-optic pulse shaper excite fluorescence from laser dye molecules in solution. Fluorescence and laser power are monitored, and the computer uses the experimental data and a genetic algorithm to optimize population transfer from ground to first excited state. Both efficiency (the ratio of excited state population to laser energy) and effectiveness (total excited state population) are optimized. Potential use as an `automated theory tester' is discussed.

  2. Warehouse stocking optimization based on dynamic ant colony genetic algorithm

    NASA Astrophysics Data System (ADS)

    Xiao, Xiaoxu

    2018-04-01

    In view of the various orders of FAW (First Automotive Works) International Logistics Co., Ltd., the SLP method is used to optimize the layout of the warehousing units in the enterprise, thus the warehouse logistics is optimized and the external processing speed of the order is improved. In addition, the relevant intelligent algorithms for optimizing the stocking route problem are analyzed. The ant colony algorithm and genetic algorithm which have good applicability are emphatically studied. The parameters of ant colony algorithm are optimized by genetic algorithm, which improves the performance of ant colony algorithm. A typical path optimization problem model is taken as an example to prove the effectiveness of parameter optimization.

  3. Enabling the extended compact genetic algorithm for real-parameter optimization by using adaptive discretization.

    PubMed

    Chen, Ying-ping; Chen, Chao-Hong

    2010-01-01

    An adaptive discretization method, called split-on-demand (SoD), enables estimation of distribution algorithms (EDAs) for discrete variables to solve continuous optimization problems. SoD randomly splits a continuous interval if the number of search points within the interval exceeds a threshold, which is decreased at every iteration. After the split operation, the nonempty intervals are assigned integer codes, and the search points are discretized accordingly. As an example of using SoD with EDAs, the integration of SoD and the extended compact genetic algorithm (ECGA) is presented and numerically examined. In this integration, we adopt a local search mechanism as an optional component of our back end optimization engine. As a result, the proposed framework can be considered as a memetic algorithm, and SoD can potentially be applied to other memetic algorithms. The numerical experiments consist of two parts: (1) a set of benchmark functions on which ECGA with SoD and ECGA with two well-known discretization methods: the fixed-height histogram (FHH) and the fixed-width histogram (FWH) are compared; (2) a real-world application, the economic dispatch problem, on which ECGA with SoD is compared to other methods. The experimental results indicate that SoD is a better discretization method to work with ECGA. Moreover, ECGA with SoD works quite well on the economic dispatch problem and delivers solutions better than the best known results obtained by other methods in existence.

  4. A controlled genetic algorithm by fuzzy logic and belief functions for job-shop scheduling.

    PubMed

    Hajri, S; Liouane, N; Hammadi, S; Borne, P

    2000-01-01

    Most scheduling problems are highly complex combinatorial problems. However, stochastic methods such as genetic algorithm yield good solutions. In this paper, we present a controlled genetic algorithm (CGA) based on fuzzy logic and belief functions to solve job-shop scheduling problems. For better performance, we propose an efficient representational scheme, heuristic rules for creating the initial population, and a new methodology for mixing and computing genetic operator probabilities.

  5. Intelligent inversion method for pre-stack seismic big data based on MapReduce

    NASA Astrophysics Data System (ADS)

    Yan, Xuesong; Zhu, Zhixin; Wu, Qinghua

    2018-01-01

    Seismic exploration is a method of oil exploration that uses seismic information; that is, according to the inversion of seismic information, the useful information of the reservoir parameters can be obtained to carry out exploration effectively. Pre-stack data are characterised by a large amount of data, abundant information, and so on, and according to its inversion, the abundant information of the reservoir parameters can be obtained. Owing to the large amount of pre-stack seismic data, existing single-machine environments have not been able to meet the computational needs of the huge amount of data; thus, the development of a method with a high efficiency and the speed to solve the inversion problem of pre-stack seismic data is urgently needed. The optimisation of the elastic parameters by using a genetic algorithm easily falls into a local optimum, which results in a non-obvious inversion effect, especially for the optimisation effect of the density. Therefore, an intelligent optimisation algorithm is proposed in this paper and used for the elastic parameter inversion of pre-stack seismic data. This algorithm improves the population initialisation strategy by using the Gardner formula and the genetic operation of the algorithm, and the improved algorithm obtains better inversion results when carrying out a model test with logging data. All of the elastic parameters obtained by inversion and the logging curve of theoretical model are fitted well, which effectively improves the inversion precision of the density. This algorithm was implemented with a MapReduce model to solve the seismic big data inversion problem. The experimental results show that the parallel model can effectively reduce the running time of the algorithm.

  6. A new three-dimensional manufacturing service composition method under various structures using improved Flower Pollination Algorithm

    NASA Astrophysics Data System (ADS)

    Zhang, Wenyu; Yang, Yushu; Zhang, Shuai; Yu, Dejian; Chen, Yong

    2018-05-01

    With the growing complexity of customer requirements and the increasing scale of manufacturing services, how to select and combine the single services to meet the complex demand of the customer has become a growing concern. This paper presents a new manufacturing service composition method to solve the multi-objective optimization problem based on quality of service (QoS). The proposed model not only presents different methods for calculating the transportation time and transportation cost under various structures but also solves the three-dimensional composition optimization problem, including service aggregation, service selection, and service scheduling simultaneously. Further, an improved Flower Pollination Algorithm (IFPA) is proposed to solve the three-dimensional composition optimization problem using a matrix-based representation scheme. The mutation operator and crossover operator of the Differential Evolution (DE) algorithm are also used to extend the basic Flower Pollination Algorithm (FPA) to improve its performance. Compared to Genetic Algorithm, DE, and basic FPA, the experimental results confirm that the proposed method demonstrates superior performance than other meta heuristic algorithms and can obtain better manufacturing service composition solutions.

  7. Forecasting Nonlinear Chaotic Time Series with Function Expression Method Based on an Improved Genetic-Simulated Annealing Algorithm

    PubMed Central

    Wang, Jun; Zhou, Bi-hua; Zhou, Shu-dao; Sheng, Zheng

    2015-01-01

    The paper proposes a novel function expression method to forecast chaotic time series, using an improved genetic-simulated annealing (IGSA) algorithm to establish the optimum function expression that describes the behavior of time series. In order to deal with the weakness associated with the genetic algorithm, the proposed algorithm incorporates the simulated annealing operation which has the strong local search ability into the genetic algorithm to enhance the performance of optimization; besides, the fitness function and genetic operators are also improved. Finally, the method is applied to the chaotic time series of Quadratic and Rossler maps for validation. The effect of noise in the chaotic time series is also studied numerically. The numerical results verify that the method can forecast chaotic time series with high precision and effectiveness, and the forecasting precision with certain noise is also satisfactory. It can be concluded that the IGSA algorithm is energy-efficient and superior. PMID:26000011

  8. Scalability problems of simple genetic algorithms.

    PubMed

    Thierens, D

    1999-01-01

    Scalable evolutionary computation has become an intensively studied research topic in recent years. The issue of scalability is predominant in any field of algorithmic design, but it became particularly relevant for the design of competent genetic algorithms once the scalability problems of simple genetic algorithms were understood. Here we present some of the work that has aided in getting a clear insight in the scalability problems of simple genetic algorithms. Particularly, we discuss the important issue of building block mixing. We show how the need for mixing places a boundary in the GA parameter space that, together with the boundary from the schema theorem, delimits the region where the GA converges reliably to the optimum in problems of bounded difficulty. This region shrinks rapidly with increasing problem size unless the building blocks are tightly linked in the problem coding structure. In addition, we look at how straightforward extensions of the simple genetic algorithm-namely elitism, niching, and restricted mating are not significantly improving the scalability problems.

  9. Forecasting nonlinear chaotic time series with function expression method based on an improved genetic-simulated annealing algorithm.

    PubMed

    Wang, Jun; Zhou, Bi-hua; Zhou, Shu-dao; Sheng, Zheng

    2015-01-01

    The paper proposes a novel function expression method to forecast chaotic time series, using an improved genetic-simulated annealing (IGSA) algorithm to establish the optimum function expression that describes the behavior of time series. In order to deal with the weakness associated with the genetic algorithm, the proposed algorithm incorporates the simulated annealing operation which has the strong local search ability into the genetic algorithm to enhance the performance of optimization; besides, the fitness function and genetic operators are also improved. Finally, the method is applied to the chaotic time series of Quadratic and Rossler maps for validation. The effect of noise in the chaotic time series is also studied numerically. The numerical results verify that the method can forecast chaotic time series with high precision and effectiveness, and the forecasting precision with certain noise is also satisfactory. It can be concluded that the IGSA algorithm is energy-efficient and superior.

  10. An investigation of messy genetic algorithms

    NASA Technical Reports Server (NTRS)

    Goldberg, David E.; Deb, Kalyanmoy; Korb, Bradley

    1990-01-01

    Genetic algorithms (GAs) are search procedures based on the mechanics of natural selection and natural genetics. They combine the use of string codings or artificial chromosomes and populations with the selective and juxtapositional power of reproduction and recombination to motivate a surprisingly powerful search heuristic in many problems. Despite their empirical success, there has been a long standing objection to the use of GAs in arbitrarily difficult problems. A new approach was launched. Results to a 30-bit, order-three-deception problem were obtained using a new type of genetic algorithm called a messy genetic algorithm (mGAs). Messy genetic algorithms combine the use of variable-length strings, a two-phase selection scheme, and messy genetic operators to effect a solution to the fixed-coding problem of standard simple GAs. The results of the study of mGAs in problems with nonuniform subfunction scale and size are presented. The mGA approach is summarized, both its operation and the theory of its use. Experiments on problems of varying scale, varying building-block size, and combined varying scale and size are presented.

  11. Global Optimization of a Periodic System using a Genetic Algorithm

    NASA Astrophysics Data System (ADS)

    Stucke, David; Crespi, Vincent

    2001-03-01

    We use a novel application of a genetic algorithm global optimizatin technique to find the lowest energy structures for periodic systems. We apply this technique to colloidal crystals for several different stoichiometries of binary and trinary colloidal crystals. This application of a genetic algorithm is decribed and results of likely candidate structures are presented.

  12. Using Hadoop MapReduce for Parallel Genetic Algorithms: A Comparison of the Global, Grid and Island Models.

    PubMed

    Ferrucci, Filomena; Salza, Pasquale; Sarro, Federica

    2017-06-29

    The need to improve the scalability of Genetic Algorithms (GAs) has motivated the research on Parallel Genetic Algorithms (PGAs), and different technologies and approaches have been used. Hadoop MapReduce represents one of the most mature technologies to develop parallel algorithms. Based on the fact that parallel algorithms introduce communication overhead, the aim of the present work is to understand if, and possibly when, the parallel GAs solutions using Hadoop MapReduce show better performance than sequential versions in terms of execution time. Moreover, we are interested in understanding which PGA model can be most effective among the global, grid, and island models. We empirically assessed the performance of these three parallel models with respect to a sequential GA on a software engineering problem, evaluating the execution time and the achieved speedup. We also analysed the behaviour of the parallel models in relation to the overhead produced by the use of Hadoop MapReduce and the GAs' computational effort, which gives a more machine-independent measure of these algorithms. We exploited three problem instances to differentiate the computation load and three cluster configurations based on 2, 4, and 8 parallel nodes. Moreover, we estimated the costs of the execution of the experimentation on a potential cloud infrastructure, based on the pricing of the major commercial cloud providers. The empirical study revealed that the use of PGA based on the island model outperforms the other parallel models and the sequential GA for all the considered instances and clusters. Using 2, 4, and 8 nodes, the island model achieves an average speedup over the three datasets of 1.8, 3.4, and 7.0 times, respectively. Hadoop MapReduce has a set of different constraints that need to be considered during the design and the implementation of parallel algorithms. The overhead of data store (i.e., HDFS) accesses, communication, and latency requires solutions that reduce data store operations. For this reason, the island model is more suitable for PGAs than the global and grid model, also in terms of costs when executed on a commercial cloud provider.

  13. Precise Network Modeling of Systems Genetics Data Using the Bayesian Network Webserver.

    PubMed

    Ziebarth, Jesse D; Cui, Yan

    2017-01-01

    The Bayesian Network Webserver (BNW, http://compbio.uthsc.edu/BNW ) is an integrated platform for Bayesian network modeling of biological datasets. It provides a web-based network modeling environment that seamlessly integrates advanced algorithms for probabilistic causal modeling and reasoning with Bayesian networks. BNW is designed for precise modeling of relatively small networks that contain less than 20 nodes. The structure learning algorithms used by BNW guarantee the discovery of the best (most probable) network structure given the data. To facilitate network modeling across multiple biological levels, BNW provides a very flexible interface that allows users to assign network nodes into different tiers and define the relationships between and within the tiers. This function is particularly useful for modeling systems genetics datasets that often consist of multiscalar heterogeneous genotype-to-phenotype data. BNW enables users to, within seconds or minutes, go from having a simply formatted input file containing a dataset to using a network model to make predictions about the interactions between variables and the potential effects of experimental interventions. In this chapter, we will introduce the functions of BNW and show how to model systems genetics datasets with BNW.

  14. Co-evolutionary data mining for fuzzy rules: automatic fitness function creation phase space, and experiments

    NASA Astrophysics Data System (ADS)

    Smith, James F., III; Blank, Joseph A.

    2003-03-01

    An approach is being explored that involves embedding a fuzzy logic based resource manager in an electronic game environment. Game agents can function under their own autonomous logic or human control. This approach automates the data mining problem. The game automatically creates a cleansed database reflecting the domain expert's knowledge, it calls a data mining function, a genetic algorithm, for data mining of the data base as required and allows easy evaluation of the information extracted. The co-evolutionary fitness functions, chromosomes and stopping criteria for ending the game are discussed. Genetic algorithm and genetic program based data mining procedures are discussed that automatically discover new fuzzy rules and strategies. The strategy tree concept and its relationship to co-evolutionary data mining are examined as well as the associated phase space representation of fuzzy concepts. The overlap of fuzzy concepts in phase space reduces the effective strategies available to adversaries. Co-evolutionary data mining alters the geometric properties of the overlap region known as the admissible region of phase space significantly enhancing the performance of the resource manager. Procedures for validation of the information data mined are discussed and significant experimental results provided.

  15. Aerodynamic Shape Optimization Using A Real-Number-Encoded Genetic Algorithm

    NASA Technical Reports Server (NTRS)

    Holst, Terry L.; Pulliam, Thomas H.

    2001-01-01

    A new method for aerodynamic shape optimization using a genetic algorithm with real number encoding is presented. The algorithm is used to optimize three different problems, a simple hill climbing problem, a quasi-one-dimensional nozzle problem using an Euler equation solver and a three-dimensional transonic wing problem using a nonlinear potential solver. Results indicate that the genetic algorithm is easy to implement and extremely reliable, being relatively insensitive to design space noise.

  16. Genetic algorithms as global random search methods

    NASA Technical Reports Server (NTRS)

    Peck, Charles C.; Dhawan, Atam P.

    1995-01-01

    Genetic algorithm behavior is described in terms of the construction and evolution of the sampling distributions over the space of candidate solutions. This novel perspective is motivated by analysis indicating that the schema theory is inadequate for completely and properly explaining genetic algorithm behavior. Based on the proposed theory, it is argued that the similarities of candidate solutions should be exploited directly, rather than encoding candidate solutions and then exploiting their similarities. Proportional selection is characterized as a global search operator, and recombination is characterized as the search process that exploits similarities. Sequential algorithms and many deletion methods are also analyzed. It is shown that by properly constraining the search breadth of recombination operators, convergence of genetic algorithms to a global optimum can be ensured.

  17. Genetic algorithms as global random search methods

    NASA Technical Reports Server (NTRS)

    Peck, Charles C.; Dhawan, Atam P.

    1995-01-01

    Genetic algorithm behavior is described in terms of the construction and evolution of the sampling distributions over the space of candidate solutions. This novel perspective is motivated by analysis indicating that that schema theory is inadequate for completely and properly explaining genetic algorithm behavior. Based on the proposed theory, it is argued that the similarities of candidate solutions should be exploited directly, rather than encoding candidate solution and then exploiting their similarities. Proportional selection is characterized as a global search operator, and recombination is characterized as the search process that exploits similarities. Sequential algorithms and many deletion methods are also analyzed. It is shown that by properly constraining the search breadth of recombination operators, convergence of genetic algorithms to a global optimum can be ensured.

  18. Contrast improvement of continuous wave diffuse optical tomography reconstruction by hybrid approach using least square and genetic algorithm

    NASA Astrophysics Data System (ADS)

    Patra, Rusha; Dutta, Pranab K.

    2015-07-01

    Reconstruction of the absorption coefficient of tissue with good contrast is of key importance in functional diffuse optical imaging. A hybrid approach using model-based iterative image reconstruction and a genetic algorithm is proposed to enhance the contrast of the reconstructed image. The proposed method yields an observed contrast of 98.4%, mean square error of 0.638×10-3, and object centroid error of (0.001 to 0.22) mm. Experimental validation of the proposed method has also been provided with tissue-like phantoms which shows a significant improvement in image quality and thus establishes the potential of the method for functional diffuse optical tomography reconstruction with continuous wave setup. A case study of finger joint imaging is illustrated as well to show the prospect of the proposed method in clinical diagnosis. The method can also be applied to the concentration measurement of a region of interest in a turbid medium.

  19. Central composite design and genetic algorithm applied for the optimization of ultrasonic-assisted removal of malachite green by ZnO Nanorod-loaded activated carbon.

    PubMed

    Ghaedi, M; Azad, F Nasiri; Dashtian, K; Hajati, S; Goudarzi, A; Soylak, M

    2016-10-05

    Maximum malachite green (MG) adsorption onto ZnO Nanorod-loaded activated carbon (ZnO-NR-AC) was achieved following the optimization of conditions, while the mass transfer was accelerated by ultrasonic. The central composite design (CCD) and genetic algorithm (GA) were used to estimate the effect of individual variables and their mutual interactions on the MG adsorption as response and to optimize the adsorption process. The ZnO-NR-AC surface morphology and its properties were identified via FESEM, XRD and FTIR. The adsorption equilibrium isotherm and kinetic models investigation revealed the well fit of the experimental data to Langmuir isotherm and pseudo-second-order kinetic model, respectively. It was shown that a small amount of ZnO-NR-AC (with adsorption capacity of 20mgg(-1)) is sufficient for the rapid removal of high amount of MG dye in short time (3.99min). Copyright © 2016 Elsevier B.V. All rights reserved.

  20. Central composite design and genetic algorithm applied for the optimization of ultrasonic-assisted removal of malachite green by ZnO Nanorod-loaded activated carbon

    NASA Astrophysics Data System (ADS)

    Ghaedi, M.; Azad, F. Nasiri; Dashtian, K.; Hajati, S.; Goudarzi, A.; Soylak, M.

    2016-10-01

    Maximum malachite green (MG) adsorption onto ZnO Nanorod-loaded activated carbon (ZnO-NR-AC) was achieved following the optimization of conditions, while the mass transfer was accelerated by ultrasonic. The central composite design (CCD) and genetic algorithm (GA) were used to estimate the effect of individual variables and their mutual interactions on the MG adsorption as response and to optimize the adsorption process. The ZnO-NR-AC surface morphology and its properties were identified via FESEM, XRD and FTIR. The adsorption equilibrium isotherm and kinetic models investigation revealed the well fit of the experimental data to Langmuir isotherm and pseudo-second-order kinetic model, respectively. It was shown that a small amount of ZnO-NR-AC (with adsorption capacity of 20 mg g- 1) is sufficient for the rapid removal of high amount of MG dye in short time (3.99 min).

  1. Genetic Algorithm Calibration of Probabilistic Cellular Automata for Modeling Mining Permit Activity

    USGS Publications Warehouse

    Louis, S.J.; Raines, G.L.

    2003-01-01

    We use a genetic algorithm to calibrate a spatially and temporally resolved cellular automata to model mining activity on public land in Idaho and western Montana. The genetic algorithm searches through a space of transition rule parameters of a two dimensional cellular automata model to find rule parameters that fit observed mining activity data. Previous work by one of the authors in calibrating the cellular automaton took weeks - the genetic algorithm takes a day and produces rules leading to about the same (or better) fit to observed data. These preliminary results indicate that genetic algorithms are a viable tool in calibrating cellular automata for this application. Experience gained during the calibration of this cellular automata suggests that mineral resource information is a critical factor in the quality of the results. With automated calibration, further refinements of how the mineral-resource information is provided to the cellular automaton will probably improve our model.

  2. Hybrid genetic algorithm in the Hopfield network for maximum 2-satisfiability problem

    NASA Astrophysics Data System (ADS)

    Kasihmuddin, Mohd Shareduwan Mohd; Sathasivam, Saratha; Mansor, Mohd. Asyraf

    2017-08-01

    Heuristic method was designed for finding optimal solution more quickly compared to classical methods which are too complex to comprehend. In this study, a hybrid approach that utilizes Hopfield network and genetic algorithm in doing maximum 2-Satisfiability problem (MAX-2SAT) was proposed. Hopfield neural network was used to minimize logical inconsistency in interpretations of logic clauses or program. Genetic algorithm (GA) has pioneered the implementation of methods that exploit the idea of combination and reproduce a better solution. The simulation incorporated with and without genetic algorithm will be examined by using Microsoft Visual 2013 C++ Express software. The performance of both searching techniques in doing MAX-2SAT was evaluate based on global minima ratio, ratio of satisfied clause and computation time. The result obtained form the computer simulation demonstrates the effectiveness and acceleration features of genetic algorithm in doing MAX-2SAT in Hopfield network.

  3. Genetic Algorithm for Traveling Salesman Problem with Modified Cycle Crossover Operator

    PubMed Central

    Mohamd Shoukry, Alaa; Gani, Showkat

    2017-01-01

    Genetic algorithms are evolutionary techniques used for optimization purposes according to survival of the fittest idea. These methods do not ensure optimal solutions; however, they give good approximation usually in time. The genetic algorithms are useful for NP-hard problems, especially the traveling salesman problem. The genetic algorithm depends on selection criteria, crossover, and mutation operators. To tackle the traveling salesman problem using genetic algorithms, there are various representations such as binary, path, adjacency, ordinal, and matrix representations. In this article, we propose a new crossover operator for traveling salesman problem to minimize the total distance. This approach has been linked with path representation, which is the most natural way to represent a legal tour. Computational results are also reported with some traditional path representation methods like partially mapped and order crossovers along with new cycle crossover operator for some benchmark TSPLIB instances and found improvements. PMID:29209364

  4. Genetic Algorithm for Traveling Salesman Problem with Modified Cycle Crossover Operator.

    PubMed

    Hussain, Abid; Muhammad, Yousaf Shad; Nauman Sajid, M; Hussain, Ijaz; Mohamd Shoukry, Alaa; Gani, Showkat

    2017-01-01

    Genetic algorithms are evolutionary techniques used for optimization purposes according to survival of the fittest idea. These methods do not ensure optimal solutions; however, they give good approximation usually in time. The genetic algorithms are useful for NP-hard problems, especially the traveling salesman problem. The genetic algorithm depends on selection criteria, crossover, and mutation operators. To tackle the traveling salesman problem using genetic algorithms, there are various representations such as binary, path, adjacency, ordinal, and matrix representations. In this article, we propose a new crossover operator for traveling salesman problem to minimize the total distance. This approach has been linked with path representation, which is the most natural way to represent a legal tour. Computational results are also reported with some traditional path representation methods like partially mapped and order crossovers along with new cycle crossover operator for some benchmark TSPLIB instances and found improvements.

  5. An evolutionary algorithm for large traveling salesman problems.

    PubMed

    Tsai, Huai-Kuang; Yang, Jinn-Moon; Tsai, Yuan-Fang; Kao, Cheng-Yan

    2004-08-01

    This work proposes an evolutionary algorithm, called the heterogeneous selection evolutionary algorithm (HeSEA), for solving large traveling salesman problems (TSP). The strengths and limitations of numerous well-known genetic operators are first analyzed, along with local search methods for TSPs from their solution qualities and mechanisms for preserving and adding edges. Based on this analysis, a new approach, HeSEA is proposed which integrates edge assembly crossover (EAX) and Lin-Kernighan (LK) local search, through family competition and heterogeneous pairing selection. This study demonstrates experimentally that EAX and LK can compensate for each other's disadvantages. Family competition and heterogeneous pairing selections are used to maintain the diversity of the population, which is especially useful for evolutionary algorithms in solving large TSPs. The proposed method was evaluated on 16 well-known TSPs in which the numbers of cities range from 318 to 13509. Experimental results indicate that HeSEA performs well and is very competitive with other approaches. The proposed method can determine the optimum path when the number of cities is under 10,000 and the mean solution quality is within 0.0074% above the optimum for each test problem. These findings imply that the proposed method can find tours robustly with a fixed small population and a limited family competition length in reasonable time, when used to solve large TSPs.

  6. Reconstruction of extended Petri nets from time series data and its application to signal transduction and to gene regulatory networks

    PubMed Central

    2011-01-01

    Background Network inference methods reconstruct mathematical models of molecular or genetic networks directly from experimental data sets. We have previously reported a mathematical method which is exclusively data-driven, does not involve any heuristic decisions within the reconstruction process, and deliveres all possible alternative minimal networks in terms of simple place/transition Petri nets that are consistent with a given discrete time series data set. Results We fundamentally extended the previously published algorithm to consider catalysis and inhibition of the reactions that occur in the underlying network. The results of the reconstruction algorithm are encoded in the form of an extended Petri net involving control arcs. This allows the consideration of processes involving mass flow and/or regulatory interactions. As a non-trivial test case, the phosphate regulatory network of enterobacteria was reconstructed using in silico-generated time-series data sets on wild-type and in silico mutants. Conclusions The new exact algorithm reconstructs extended Petri nets from time series data sets by finding all alternative minimal networks that are consistent with the data. It suggested alternative molecular mechanisms for certain reactions in the network. The algorithm is useful to combine data from wild-type and mutant cells and may potentially integrate physiological, biochemical, pharmacological, and genetic data in the form of a single model. PMID:21762503

  7. A New Challenge for Compression Algorithms: Genetic Sequences.

    ERIC Educational Resources Information Center

    Grumbach, Stephane; Tahi, Fariza

    1994-01-01

    Analyzes the properties of genetic sequences that cause the failure of classical algorithms used for data compression. A lossless algorithm, which compresses the information contained in DNA and RNA sequences by detecting regularities such as palindromes, is presented. This algorithm combines substitutional and statistical methods and appears to…

  8. Multicast backup reprovisioning problem for Hamiltonian cycle-based protection on WDM networks

    NASA Astrophysics Data System (ADS)

    Din, Der-Rong; Huang, Jen-Shen

    2014-03-01

    As networks grow in size and complexity, the chance and the impact of failures increase dramatically. The pre-allocated backup resources cannot provide 100% protection guarantee when continuous failures occur in a network. In this paper, the multicast backup re-provisioning problem (MBRP) for Hamiltonian cycle (HC)-based protection on WDM networks for the link-failure case is studied. We focus on how to recover the protecting capabilities of Hamiltonian cycle against the subsequent link-failures on WDM networks for multicast transmissions, after recovering the multicast trees affected by the previous link-failure. Since this problem is a hard problem, an algorithm, which consists of several heuristics and a genetic algorithm (GA), is proposed to solve it. The simulation results of the proposed method are also given. Experimental results indicate that the proposed algorithm can solve this problem efficiently.

  9. Firefly algorithm versus genetic algorithm as powerful variable selection tools and their effect on different multivariate calibration models in spectroscopy: A comparative study

    NASA Astrophysics Data System (ADS)

    Attia, Khalid A. M.; Nassar, Mohammed W. I.; El-Zeiny, Mohamed B.; Serag, Ahmed

    2017-01-01

    For the first time, a new variable selection method based on swarm intelligence namely firefly algorithm is coupled with three different multivariate calibration models namely, concentration residual augmented classical least squares, artificial neural network and support vector regression in UV spectral data. A comparative study between the firefly algorithm and the well-known genetic algorithm was developed. The discussion revealed the superiority of using this new powerful algorithm over the well-known genetic algorithm. Moreover, different statistical tests were performed and no significant differences were found between all the models regarding their predictabilities. This ensures that simpler and faster models were obtained without any deterioration of the quality of the calibration.

  10. Stochastic model search with binary outcomes for genome-wide association studies

    PubMed Central

    Malovini, Alberto; Puca, Annibale A; Bellazzi, Riccardo

    2012-01-01

    Objective The spread of case–control genome-wide association studies (GWASs) has stimulated the development of new variable selection methods and predictive models. We introduce a novel Bayesian model search algorithm, Binary Outcome Stochastic Search (BOSS), which addresses the model selection problem when the number of predictors far exceeds the number of binary responses. Materials and methods Our method is based on a latent variable model that links the observed outcomes to the underlying genetic variables. A Markov Chain Monte Carlo approach is used for model search and to evaluate the posterior probability of each predictor. Results BOSS is compared with three established methods (stepwise regression, logistic lasso, and elastic net) in a simulated benchmark. Two real case studies are also investigated: a GWAS on the genetic bases of longevity, and the type 2 diabetes study from the Wellcome Trust Case Control Consortium. Simulations show that BOSS achieves higher precisions than the reference methods while preserving good recall rates. In both experimental studies, BOSS successfully detects genetic polymorphisms previously reported to be associated with the analyzed phenotypes. Discussion BOSS outperforms the other methods in terms of F-measure on simulated data. In the two real studies, BOSS successfully detects biologically relevant features, some of which are missed by univariate analysis and the three reference techniques. Conclusion The proposed algorithm is an advance in the methodology for model selection with a large number of features. Our simulated and experimental results showed that BOSS proves effective in detecting relevant markers while providing a parsimonious model. PMID:22534080

  11. Refined genetic algorithm -- Economic dispatch example

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sheble, G.B.; Brittig, K.

    1995-02-01

    A genetic-based algorithm is used to solve an economic dispatch (ED) problem. The algorithm utilizes payoff information of perspective solutions to evaluate optimality. Thus, the constraints of classical LaGrangian techniques on unit curves are eliminated. Using an economic dispatch problem as a basis for comparison, several different techniques which enhance program efficiency and accuracy, such as mutation prediction, elitism, interval approximation and penalty factors, are explored. Two unique genetic algorithms are also compared. The results are verified for a sample problem using a classical technique.

  12. Genetic algorithms in conceptual design of a light-weight, low-noise, tilt-rotor aircraft

    NASA Technical Reports Server (NTRS)

    Wells, Valana L.

    1996-01-01

    This report outlines research accomplishments in the area of using genetic algorithms (GA) for the design and optimization of rotorcraft. It discusses the genetic algorithm as a search and optimization tool, outlines a procedure for using the GA in the conceptual design of helicopters, and applies the GA method to the acoustic design of rotors.

  13. Self-calibration of a noisy multiple-sensor system with genetic algorithms

    NASA Astrophysics Data System (ADS)

    Brooks, Richard R.; Iyengar, S. Sitharama; Chen, Jianhua

    1996-01-01

    This paper explores an image processing application of optimization techniques which entails interpreting noisy sensor data. The application is a generalization of image correlation; we attempt to find the optimal gruence which matches two overlapping gray-scale images corrupted with noise. Both taboo search and genetic algorithms are used to find the parameters which match the two images. A genetic algorithm approach using an elitist reproduction scheme is found to provide significantly superior results. The presentation includes a graphic presentation of the paths taken by tabu search and genetic algorithms when trying to find the best possible match between two corrupted images.

  14. Estimating the kinetic parameters of activated sludge storage using weighted non-linear least-squares and accelerating genetic algorithm.

    PubMed

    Fang, Fang; Ni, Bing-Jie; Yu, Han-Qing

    2009-06-01

    In this study, weighted non-linear least-squares analysis and accelerating genetic algorithm are integrated to estimate the kinetic parameters of substrate consumption and storage product formation of activated sludge. A storage product formation equation is developed and used to construct the objective function for the determination of its production kinetics. The weighted least-squares analysis is employed to calculate the differences in the storage product concentration between the model predictions and the experimental data as the sum of squared weighted errors. The kinetic parameters for the substrate consumption and the storage product formation are estimated to be the maximum heterotrophic growth rate of 0.121/h, the yield coefficient of 0.44 mg CODX/mg CODS (COD, chemical oxygen demand) and the substrate half saturation constant of 16.9 mg/L, respectively, by minimizing the objective function using a real-coding-based accelerating genetic algorithm. Also, the fraction of substrate electrons diverted to the storage product formation is estimated to be 0.43 mg CODSTO/mg CODS. The validity of our approach is confirmed by the results of independent tests and the kinetic parameter values reported in literature, suggesting that this approach could be useful to evaluate the product formation kinetics of mixed cultures like activated sludge. More importantly, as this integrated approach could estimate the kinetic parameters rapidly and accurately, it could be applied to other biological processes.

  15. A Linear Electromagnetic Piston Pump

    NASA Astrophysics Data System (ADS)

    Hogan, Paul H.

    Advancements in mobile hydraulics for human-scale applications have increased demand for a compact hydraulic power supply. Conventional designs couple a rotating electric motor to a hydraulic pump, which increases the package volume and requires several energy conversions. This thesis investigates the use of a free piston as the moving element in a linear motor to eliminate multiple energy conversions and decrease the overall package volume. A coupled model used a quasi-static magnetic equivalent circuit to calculate the motor inductance and the electromagnetic force acting on the piston. The force was an input to a time domain model to evaluate the mechanical and pressure dynamics. The magnetic circuit model was validated with finite element analysis and an experimental prototype linear motor. The coupled model was optimized using a multi-objective genetic algorithm to explore the parameter space and maximize power density and efficiency. An experimental prototype linear pump coupled pistons to an off-the-shelf linear motor to validate the mechanical and pressure dynamics models. The magnetic circuit force calculation agreed within 3% of finite element analysis, and within 8% of experimental data from the unoptimized prototype linear motor. The optimized motor geometry also had good agreement with FEA; at zero piston displacement, the magnetic circuit calculates optimized motor force within 10% of FEA in less than 1/1000 the computational time. This makes it well suited to genetic optimization algorithms. The mechanical model agrees very well with the experimental piston pump position data when tuned for additional unmodeled mechanical friction. Optimized results suggest that an improvement of 400% of the state of the art power density is attainable with as high as 85% net efficiency. This demonstrates that a linear electromagnetic piston pump has potential to serve as a more compact and efficient supply of fluid power for the human scale.

  16. Genetic Algorithms Applied to Multi-Objective Aerodynamic Shape Optimization

    NASA Technical Reports Server (NTRS)

    Holst, Terry L.

    2004-01-01

    A genetic algorithm approach suitable for solving multi-objective optimization problems is described and evaluated using a series of aerodynamic shape optimization problems. Several new features including two variations of a binning selection algorithm and a gene-space transformation procedure are included. The genetic algorithm is suitable for finding pareto optimal solutions in search spaces that are defined by any number of genes and that contain any number of local extrema. A new masking array capability is included allowing any gene or gene subset to be eliminated as decision variables from the design space. This allows determination of the effect of a single gene or gene subset on the pareto optimal solution. Results indicate that the genetic algorithm optimization approach is flexible in application and reliable. The binning selection algorithms generally provide pareto front quality enhancements and moderate convergence efficiency improvements for most of the problems solved.

  17. Genetic Algorithms Applied to Multi-Objective Aerodynamic Shape Optimization

    NASA Technical Reports Server (NTRS)

    Holst, Terry L.

    2005-01-01

    A genetic algorithm approach suitable for solving multi-objective problems is described and evaluated using a series of aerodynamic shape optimization problems. Several new features including two variations of a binning selection algorithm and a gene-space transformation procedure are included. The genetic algorithm is suitable for finding Pareto optimal solutions in search spaces that are defined by any number of genes and that contain any number of local extrema. A new masking array capability is included allowing any gene or gene subset to be eliminated as decision variables from the design space. This allows determination of the effect of a single gene or gene subset on the Pareto optimal solution. Results indicate that the genetic algorithm optimization approach is flexible in application and reliable. The binning selection algorithms generally provide Pareto front quality enhancements and moderate convergence efficiency improvements for most of the problems solved.

  18. Genetic algorithm dynamics on a rugged landscape

    NASA Astrophysics Data System (ADS)

    Bornholdt, Stefan

    1998-04-01

    The genetic algorithm is an optimization procedure motivated by biological evolution and is successfully applied to optimization problems in different areas. A statistical mechanics model for its dynamics is proposed based on the parent-child fitness correlation of the genetic operators, making it applicable to general fitness landscapes. It is compared to a recent model based on a maximum entropy ansatz. Finally it is applied to modeling the dynamics of a genetic algorithm on the rugged fitness landscape of the NK model.

  19. High-volume optical vortex multiplexing and de-multiplexing for free-space optical communication.

    PubMed

    Wang, Zhongxi; Zhang, N; Yuan, X-C

    2011-01-17

    We report an approach to the increase of signal channels in free-space optical communication based on composed optical vortices (OVs). In the encoding process, conventional algorithm employed for the generation of collinearly superimposed OVs is combined with a genetic algorithm to achieve high-volume OV multiplexing. At the receiver end, a novel Dammann vortex grating is used to analyze the multihelix beams with a large number of OVs. We experimentally demonstrate a digitized system which is capable of transmitting and receiving 16 OV channels simultaneously. This system is expected to be compatible with a high-speed OV multiplexing technique, with potentials to extremely high-volume information density in OV communication.

  20. A novel framework of tissue membrane systems for image fusion.

    PubMed

    Zhang, Zulin; Yi, Xinzhong; Peng, Hong

    2014-01-01

    This paper proposes a tissue membrane system-based framework to deal with the optimal image fusion problem. A spatial domain fusion algorithm is given, and a tissue membrane system of multiple cells is used as its computing framework. Based on the multicellular structure and inherent communication mechanism of the tissue membrane system, an improved velocity-position model is developed. The performance of the fusion framework is studied with comparison of several traditional fusion methods as well as genetic algorithm (GA)-based and differential evolution (DE)-based spatial domain fusion methods. Experimental results show that the proposed fusion framework is superior or comparable to the other methods and can be efficiently used for image fusion.

  1. Sequential and Mixed Genetic Algorithm and Learning Automata (SGALA, MGALA) for Feature Selection in QSAR

    PubMed Central

    MotieGhader, Habib; Gharaghani, Sajjad; Masoudi-Sobhanzadeh, Yosef; Masoudi-Nejad, Ali

    2017-01-01

    Feature selection is of great importance in Quantitative Structure-Activity Relationship (QSAR) analysis. This problem has been solved using some meta-heuristic algorithms such as GA, PSO, ACO and so on. In this work two novel hybrid meta-heuristic algorithms i.e. Sequential GA and LA (SGALA) and Mixed GA and LA (MGALA), which are based on Genetic algorithm and learning automata for QSAR feature selection are proposed. SGALA algorithm uses advantages of Genetic algorithm and Learning Automata sequentially and the MGALA algorithm uses advantages of Genetic Algorithm and Learning Automata simultaneously. We applied our proposed algorithms to select the minimum possible number of features from three different datasets and also we observed that the MGALA and SGALA algorithms had the best outcome independently and in average compared to other feature selection algorithms. Through comparison of our proposed algorithms, we deduced that the rate of convergence to optimal result in MGALA and SGALA algorithms were better than the rate of GA, ACO, PSO and LA algorithms. In the end, the results of GA, ACO, PSO, LA, SGALA, and MGALA algorithms were applied as the input of LS-SVR model and the results from LS-SVR models showed that the LS-SVR model had more predictive ability with the input from SGALA and MGALA algorithms than the input from all other mentioned algorithms. Therefore, the results have corroborated that not only is the predictive efficiency of proposed algorithms better, but their rate of convergence is also superior to the all other mentioned algorithms. PMID:28979308

  2. Sequential and Mixed Genetic Algorithm and Learning Automata (SGALA, MGALA) for Feature Selection in QSAR.

    PubMed

    MotieGhader, Habib; Gharaghani, Sajjad; Masoudi-Sobhanzadeh, Yosef; Masoudi-Nejad, Ali

    2017-01-01

    Feature selection is of great importance in Quantitative Structure-Activity Relationship (QSAR) analysis. This problem has been solved using some meta-heuristic algorithms such as GA, PSO, ACO and so on. In this work two novel hybrid meta-heuristic algorithms i.e. Sequential GA and LA (SGALA) and Mixed GA and LA (MGALA), which are based on Genetic algorithm and learning automata for QSAR feature selection are proposed. SGALA algorithm uses advantages of Genetic algorithm and Learning Automata sequentially and the MGALA algorithm uses advantages of Genetic Algorithm and Learning Automata simultaneously. We applied our proposed algorithms to select the minimum possible number of features from three different datasets and also we observed that the MGALA and SGALA algorithms had the best outcome independently and in average compared to other feature selection algorithms. Through comparison of our proposed algorithms, we deduced that the rate of convergence to optimal result in MGALA and SGALA algorithms were better than the rate of GA, ACO, PSO and LA algorithms. In the end, the results of GA, ACO, PSO, LA, SGALA, and MGALA algorithms were applied as the input of LS-SVR model and the results from LS-SVR models showed that the LS-SVR model had more predictive ability with the input from SGALA and MGALA algorithms than the input from all other mentioned algorithms. Therefore, the results have corroborated that not only is the predictive efficiency of proposed algorithms better, but their rate of convergence is also superior to the all other mentioned algorithms.

  3. Focusing ISAR Images using Fast Adaptive Time-Frequency and 3D Motion Detection on Simulated and Experimental Radar Data

    DTIC Science & Technology

    2005-06-01

    Time Fourier Transform WVD Wigner - Ville Distribution GA Genetic Algorithm PSO Particle Swarm Optimization JEM Jet Engine Modulation CPI...of the Wigner - Ville Distribution ( WVD ), cross-terms appear in the time-frequency image. As shown in Figure 9, which is a WVD of range bin 31 of...14 Figure 9. Wigner - Ville Distribution of Unfocused Range Bin 31 (After [3] and [5].) ...15

  4. Random forests on Hadoop for genome-wide association studies of multivariate neuroimaging phenotypes

    PubMed Central

    2013-01-01

    Motivation Multivariate quantitative traits arise naturally in recent neuroimaging genetics studies, in which both structural and functional variability of the human brain is measured non-invasively through techniques such as magnetic resonance imaging (MRI). There is growing interest in detecting genetic variants associated with such multivariate traits, especially in genome-wide studies. Random forests (RFs) classifiers, which are ensembles of decision trees, are amongst the best performing machine learning algorithms and have been successfully employed for the prioritisation of genetic variants in case-control studies. RFs can also be applied to produce gene rankings in association studies with multivariate quantitative traits, and to estimate genetic similarities measures that are predictive of the trait. However, in studies involving hundreds of thousands of SNPs and high-dimensional traits, a very large ensemble of trees must be inferred from the data in order to obtain reliable rankings, which makes the application of these algorithms computationally prohibitive. Results We have developed a parallel version of the RF algorithm for regression and genetic similarity learning tasks in large-scale population genetic association studies involving multivariate traits, called PaRFR (Parallel Random Forest Regression). Our implementation takes advantage of the MapReduce programming model and is deployed on Hadoop, an open-source software framework that supports data-intensive distributed applications. Notable speed-ups are obtained by introducing a distance-based criterion for node splitting in the tree estimation process. PaRFR has been applied to a genome-wide association study on Alzheimer's disease (AD) in which the quantitative trait consists of a high-dimensional neuroimaging phenotype describing longitudinal changes in the human brain structure. PaRFR provides a ranking of SNPs associated to this trait, and produces pair-wise measures of genetic proximity that can be directly compared to pair-wise measures of phenotypic proximity. Several known AD-related variants have been identified, including APOE4 and TOMM40. We also present experimental evidence supporting the hypothesis of a linear relationship between the number of top-ranked mutated states, or frequent mutation patterns, and an indicator of disease severity. Availability The Java codes are freely available at http://www2.imperial.ac.uk/~gmontana. PMID:24564704

  5. Random forests on Hadoop for genome-wide association studies of multivariate neuroimaging phenotypes.

    PubMed

    Wang, Yue; Goh, Wilson; Wong, Limsoon; Montana, Giovanni

    2013-01-01

    Multivariate quantitative traits arise naturally in recent neuroimaging genetics studies, in which both structural and functional variability of the human brain is measured non-invasively through techniques such as magnetic resonance imaging (MRI). There is growing interest in detecting genetic variants associated with such multivariate traits, especially in genome-wide studies. Random forests (RFs) classifiers, which are ensembles of decision trees, are amongst the best performing machine learning algorithms and have been successfully employed for the prioritisation of genetic variants in case-control studies. RFs can also be applied to produce gene rankings in association studies with multivariate quantitative traits, and to estimate genetic similarities measures that are predictive of the trait. However, in studies involving hundreds of thousands of SNPs and high-dimensional traits, a very large ensemble of trees must be inferred from the data in order to obtain reliable rankings, which makes the application of these algorithms computationally prohibitive. We have developed a parallel version of the RF algorithm for regression and genetic similarity learning tasks in large-scale population genetic association studies involving multivariate traits, called PaRFR (Parallel Random Forest Regression). Our implementation takes advantage of the MapReduce programming model and is deployed on Hadoop, an open-source software framework that supports data-intensive distributed applications. Notable speed-ups are obtained by introducing a distance-based criterion for node splitting in the tree estimation process. PaRFR has been applied to a genome-wide association study on Alzheimer's disease (AD) in which the quantitative trait consists of a high-dimensional neuroimaging phenotype describing longitudinal changes in the human brain structure. PaRFR provides a ranking of SNPs associated to this trait, and produces pair-wise measures of genetic proximity that can be directly compared to pair-wise measures of phenotypic proximity. Several known AD-related variants have been identified, including APOE4 and TOMM40. We also present experimental evidence supporting the hypothesis of a linear relationship between the number of top-ranked mutated states, or frequent mutation patterns, and an indicator of disease severity. The Java codes are freely available at http://www2.imperial.ac.uk/~gmontana.

  6. An Improved Hierarchical Genetic Algorithm for Sheet Cutting Scheduling with Process Constraints

    PubMed Central

    Rao, Yunqing; Qi, Dezhong; Li, Jinling

    2013-01-01

    For the first time, an improved hierarchical genetic algorithm for sheet cutting problem which involves n cutting patterns for m non-identical parallel machines with process constraints has been proposed in the integrated cutting stock model. The objective of the cutting scheduling problem is minimizing the weighted completed time. A mathematical model for this problem is presented, an improved hierarchical genetic algorithm (ant colony—hierarchical genetic algorithm) is developed for better solution, and a hierarchical coding method is used based on the characteristics of the problem. Furthermore, to speed up convergence rates and resolve local convergence issues, a kind of adaptive crossover probability and mutation probability is used in this algorithm. The computational result and comparison prove that the presented approach is quite effective for the considered problem. PMID:24489491

  7. An improved hierarchical genetic algorithm for sheet cutting scheduling with process constraints.

    PubMed

    Rao, Yunqing; Qi, Dezhong; Li, Jinling

    2013-01-01

    For the first time, an improved hierarchical genetic algorithm for sheet cutting problem which involves n cutting patterns for m non-identical parallel machines with process constraints has been proposed in the integrated cutting stock model. The objective of the cutting scheduling problem is minimizing the weighted completed time. A mathematical model for this problem is presented, an improved hierarchical genetic algorithm (ant colony--hierarchical genetic algorithm) is developed for better solution, and a hierarchical coding method is used based on the characteristics of the problem. Furthermore, to speed up convergence rates and resolve local convergence issues, a kind of adaptive crossover probability and mutation probability is used in this algorithm. The computational result and comparison prove that the presented approach is quite effective for the considered problem.

  8. CamOptimus: a tool for exploiting complex adaptive evolution to optimize experiments and processes in biotechnology

    PubMed Central

    Cankorur-Cetinkaya, Ayca; Dias, Joao M. L.; Kludas, Jana; Slater, Nigel K. H.; Rousu, Juho; Dikicioglu, Duygu

    2017-01-01

    Multiple interacting factors affect the performance of engineered biological systems in synthetic biology projects. The complexity of these biological systems means that experimental design should often be treated as a multiparametric optimization problem. However, the available methodologies are either impractical, due to a combinatorial explosion in the number of experiments to be performed, or are inaccessible to most experimentalists due to the lack of publicly available, user-friendly software. Although evolutionary algorithms may be employed as alternative approaches to optimize experimental design, the lack of simple-to-use software again restricts their use to specialist practitioners. In addition, the lack of subsidiary approaches to further investigate critical factors and their interactions prevents the full analysis and exploitation of the biotechnological system. We have addressed these problems and, here, provide a simple‐to‐use and freely available graphical user interface to empower a broad range of experimental biologists to employ complex evolutionary algorithms to optimize their experimental designs. Our approach exploits a Genetic Algorithm to discover the subspace containing the optimal combination of parameters, and Symbolic Regression to construct a model to evaluate the sensitivity of the experiment to each parameter under investigation. We demonstrate the utility of this method using an example in which the culture conditions for the microbial production of a bioactive human protein are optimized. CamOptimus is available through: (https://doi.org/10.17863/CAM.10257). PMID:28635591

  9. Pose estimation for augmented reality applications using genetic algorithm.

    PubMed

    Yu, Ying Kin; Wong, Kin Hong; Chang, Michael Ming Yuen

    2005-12-01

    This paper describes a genetic algorithm that tackles the pose-estimation problem in computer vision. Our genetic algorithm can find the rotation and translation of an object accurately when the three-dimensional structure of the object is given. In our implementation, each chromosome encodes both the pose and the indexes to the selected point features of the object. Instead of only searching for the pose as in the existing work, our algorithm, at the same time, searches for a set containing the most reliable feature points in the process. This mismatch filtering strategy successfully makes the algorithm more robust under the presence of point mismatches and outliers in the images. Our algorithm has been tested with both synthetic and real data with good results. The accuracy of the recovered pose is compared to the existing algorithms. Our approach outperformed the Lowe's method and the other two genetic algorithms under the presence of point mismatches and outliers. In addition, it has been used to estimate the pose of a real object. It is shown that the proposed method is applicable to augmented reality applications.

  10. Optimization of laminated stacking sequence for buckling load maximization by genetic algorithm

    NASA Technical Reports Server (NTRS)

    Le Riche, Rodolphe; Haftka, Raphael T.

    1992-01-01

    The use of a genetic algorithm to optimize the stacking sequence of a composite laminate for buckling load maximization is studied. Various genetic parameters including the population size, the probability of mutation, and the probability of crossover are optimized by numerical experiments. A new genetic operator - permutation - is proposed and shown to be effective in reducing the cost of the genetic search. Results are obtained for a graphite-epoxy plate, first when only the buckling load is considered, and then when constraints on ply contiguity and strain failure are added. The influence on the genetic search of the penalty parameter enforcing the contiguity constraint is studied. The advantage of the genetic algorithm in producing several near-optimal designs is discussed.

  11. Development of a Tool for an Efficient Calibration of CORSIM Models

    DOT National Transportation Integrated Search

    2014-08-01

    This project proposes a Memetic Algorithm (MA) for the calibration of microscopic traffic flow simulation models. The proposed MA includes a combination of genetic and simulated annealing algorithms. The genetic algorithm performs the exploration of ...

  12. Engineered Intrinsic Bioremediation of Ammonium Perchlorate in Groundwater

    DTIC Science & Technology

    2010-12-01

    German Collection of Microorganisms and Cell Cultures) GA Genetic Algorithms GA-ANN Genetic Algorithm Artificial Neural Network GMO genetically...for in situ treatment of perchlorate in groundwater. This is accomplished without the addition of genetically engineered microorganisms ( GMOs ) to the...perchlorate, even in the presence of oxygen and without the addition of genetically engineered microorganisms ( GMOs ) to the environment. This approach

  13. [Algorithm of toxigenic genetically altered Vibrio cholerae El Tor biovar strain identification].

    PubMed

    Smirnova, N I; Agafonov, D A; Zadnova, S P; Cherkasov, A V; Kutyrev, V V

    2014-01-01

    Development of an algorithm of genetically altered Vibrio cholerae biovar El Tor strai identification that ensures determination of serogroup, serovar and biovar of the studied isolate based on pheno- and genotypic properties, detection of genetically altered cholera El Tor causative agents, their differentiation by epidemic potential as well as evaluation of variability of key pathogenicity genes. Complex analysis of 28 natural V. cholerae strains was carried out by using traditional microbiological methods, PCR and fragmentary sequencing. An algorithm of toxigenic genetically altered V. cholerae biovar El Tor strain identification was developed that includes 4 stages: determination of serogroup, serovar and biovar based on phenotypic properties, confirmation of serogroup and biovar based on molecular-genetic properties determination of strains as genetically altered, differentiation of genetically altered strains by their epidemic potential and detection of ctxB and tcpA key pathogenicity gene polymorphism. The algorithm is based on the use of traditional microbiological methods, PCR and sequencing of gene fragments. The use of the developed algorithm will increase the effectiveness of detection of genetically altered variants of the cholera El Tor causative agent, their differentiation by epidemic potential and will ensure establishment of polymorphism of genes that code key pathogenicity factors for determination of origins of the strains and possible routes of introduction of the infection.

  14. Firefly algorithm versus genetic algorithm as powerful variable selection tools and their effect on different multivariate calibration models in spectroscopy: A comparative study.

    PubMed

    Attia, Khalid A M; Nassar, Mohammed W I; El-Zeiny, Mohamed B; Serag, Ahmed

    2017-01-05

    For the first time, a new variable selection method based on swarm intelligence namely firefly algorithm is coupled with three different multivariate calibration models namely, concentration residual augmented classical least squares, artificial neural network and support vector regression in UV spectral data. A comparative study between the firefly algorithm and the well-known genetic algorithm was developed. The discussion revealed the superiority of using this new powerful algorithm over the well-known genetic algorithm. Moreover, different statistical tests were performed and no significant differences were found between all the models regarding their predictabilities. This ensures that simpler and faster models were obtained without any deterioration of the quality of the calibration. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. An image segmentation method based on fuzzy C-means clustering and Cuckoo search algorithm

    NASA Astrophysics Data System (ADS)

    Wang, Mingwei; Wan, Youchuan; Gao, Xianjun; Ye, Zhiwei; Chen, Maolin

    2018-04-01

    Image segmentation is a significant step in image analysis and machine vision. Many approaches have been presented in this topic; among them, fuzzy C-means (FCM) clustering is one of the most widely used methods for its high efficiency and ambiguity of images. However, the success of FCM could not be guaranteed because it easily traps into local optimal solution. Cuckoo search (CS) is a novel evolutionary algorithm, which has been tested on some optimization problems and proved to be high-efficiency. Therefore, a new segmentation technique using FCM and blending of CS algorithm is put forward in the paper. Further, the proposed method has been measured on several images and compared with other existing FCM techniques such as genetic algorithm (GA) based FCM and particle swarm optimization (PSO) based FCM in terms of fitness value. Experimental results indicate that the proposed method is robust, adaptive and exhibits the better performance than other methods involved in the paper.

  16. Damage identification of a TLP floating wind turbine by meta-heuristic algorithms

    NASA Astrophysics Data System (ADS)

    Ettefagh, M. M.

    2015-12-01

    Damage identification of the offshore floating wind turbine by vibration/dynamic signals is one of the important and new research fields in the Structural Health Monitoring (SHM). In this paper a new damage identification method is proposed based on meta-heuristic algorithms using the dynamic response of the TLP (Tension-Leg Platform) floating wind turbine structure. The Genetic Algorithms (GA), Artificial Immune System (AIS), Particle Swarm Optimization (PSO), and Artificial Bee Colony (ABC) are chosen for minimizing the object function, defined properly for damage identification purpose. In addition to studying the capability of mentioned algorithms in correctly identifying the damage, the effect of the response type on the results of identification is studied. Also, the results of proposed damage identification are investigated with considering possible uncertainties of the structure. Finally, for evaluating the proposed method in real condition, a 1/100 scaled experimental setup of TLP Floating Wind Turbine (TLPFWT) is provided in a laboratory scale and the proposed damage identification method is applied to the scaled turbine.

  17. Speckle-reduction algorithm for ultrasound images in complex wavelet domain using genetic algorithm-based mixture model.

    PubMed

    Uddin, Muhammad Shahin; Tahtali, Murat; Lambert, Andrew J; Pickering, Mark R; Marchese, Margaret; Stuart, Iain

    2016-05-20

    Compared with other medical-imaging modalities, ultrasound (US) imaging is a valuable way to examine the body's internal organs, and two-dimensional (2D) imaging is currently the most common technique used in clinical diagnoses. Conventional 2D US imaging systems are highly flexible cost-effective imaging tools that permit operators to observe and record images of a large variety of thin anatomical sections in real time. Recently, 3D US imaging has also been gaining popularity due to its considerable advantages over 2D US imaging. It reduces dependency on the operator and provides better qualitative and quantitative information for an effective diagnosis. Furthermore, it provides a 3D view, which allows the observation of volume information. The major shortcoming of any type of US imaging is the presence of speckle noise. Hence, speckle reduction is vital in providing a better clinical diagnosis. The key objective of any speckle-reduction algorithm is to attain a speckle-free image while preserving the important anatomical features. In this paper we introduce a nonlinear multi-scale complex wavelet-diffusion based algorithm for speckle reduction and sharp-edge preservation of 2D and 3D US images. In the proposed method we use a Rayleigh and Maxwell-mixture model for 2D and 3D US images, respectively, where a genetic algorithm is used in combination with an expectation maximization method to estimate mixture parameters. Experimental results using both 2D and 3D synthetic, physical phantom, and clinical data demonstrate that our proposed algorithm significantly reduces speckle noise while preserving sharp edges without discernible distortions. The proposed approach performs better than the state-of-the-art approaches in both qualitative and quantitative measures.

  18. Evolving aerodynamic airfoils for wind turbines through a genetic algorithm

    NASA Astrophysics Data System (ADS)

    Hernández, J. J.; Gómez, E.; Grageda, J. I.; Couder, C.; Solís, A.; Hanotel, C. L.; Ledesma, JI

    2017-01-01

    Nowadays, genetic algorithms stand out for airfoil optimisation, due to the virtues of mutation and crossing-over techniques. In this work we propose a genetic algorithm with arithmetic crossover rules. The optimisation criteria are taken to be the maximisation of both aerodynamic efficiency and lift coefficient, while minimising drag coefficient. Such algorithm shows greatly improvements in computational costs, as well as a high performance by obtaining optimised airfoils for Mexico City's specific wind conditions from generic wind turbines designed for higher Reynolds numbers, in few iterations.

  19. An Agent Inspired Reconfigurable Computing Implementation of a Genetic Algorithm

    NASA Technical Reports Server (NTRS)

    Weir, John M.; Wells, B. Earl

    2003-01-01

    Many software systems have been successfully implemented using an agent paradigm which employs a number of independent entities that communicate with one another to achieve a common goal. The distributed nature of such a paradigm makes it an excellent candidate for use in high speed reconfigurable computing hardware environments such as those present in modem FPGA's. In this paper, a distributed genetic algorithm that can be applied to the agent based reconfigurable hardware model is introduced. The effectiveness of this new algorithm is evaluated by comparing the quality of the solutions found by the new algorithm with those found by traditional genetic algorithms. The performance of a reconfigurable hardware implementation of the new algorithm on an FPGA is compared to traditional single processor implementations.

  20. A novel color image encryption algorithm based on genetic recombination and the four-dimensional memristive hyperchaotic system

    NASA Astrophysics Data System (ADS)

    Chai, Xiu-Li; Gan, Zhi-Hua; Lu, Yang; Zhang, Miao-Hui; Chen, Yi-Ran

    2016-10-01

    Recently, many image encryption algorithms based on chaos have been proposed. Most of the previous algorithms encrypt components R, G, and B of color images independently and neglect the high correlation between them. In the paper, a novel color image encryption algorithm is introduced. The 24 bit planes of components R, G, and B of the color plain image are obtained and recombined into 4 compound bit planes, and this can make the three components affect each other. A four-dimensional (4D) memristive hyperchaotic system generates the pseudorandom key streams and its initial values come from the SHA 256 hash value of the color plain image. The compound bit planes and key streams are confused according to the principles of genetic recombination, then confusion and diffusion as a union are applied to the bit planes, and the color cipher image is obtained. Experimental results and security analyses demonstrate that the proposed algorithm is secure and effective so that it may be adopted for secure communication. Project supported by the National Natural Science Foundation of China (Grant Nos. 61203094 and 61305042), the Natural Science Foundation of the United States (Grant Nos. CNS-1253424 and ECCS-1202225), the Science and Technology Foundation of Henan Province, China (Grant No. 152102210048), the Foundation and Frontier Project of Henan Province, China (Grant No. 162300410196), the Natural Science Foundation of Educational Committee of Henan Province, China (Grant No. 14A413015), and the Research Foundation of Henan University, China (Grant No. xxjc20140006).

  1. Review: Optimization methods for groundwater modeling and management

    NASA Astrophysics Data System (ADS)

    Yeh, William W.-G.

    2015-09-01

    Optimization methods have been used in groundwater modeling as well as for the planning and management of groundwater systems. This paper reviews and evaluates the various optimization methods that have been used for solving the inverse problem of parameter identification (estimation), experimental design, and groundwater planning and management. Various model selection criteria are discussed, as well as criteria used for model discrimination. The inverse problem of parameter identification concerns the optimal determination of model parameters using water-level observations. In general, the optimal experimental design seeks to find sampling strategies for the purpose of estimating the unknown model parameters. A typical objective of optimal conjunctive-use planning of surface water and groundwater is to minimize the operational costs of meeting water demand. The optimization methods include mathematical programming techniques such as linear programming, quadratic programming, dynamic programming, stochastic programming, nonlinear programming, and the global search algorithms such as genetic algorithms, simulated annealing, and tabu search. Emphasis is placed on groundwater flow problems as opposed to contaminant transport problems. A typical two-dimensional groundwater flow problem is used to explain the basic formulations and algorithms that have been used to solve the formulated optimization problems.

  2. Improving experimental phases for strong reflections prior to density modification

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Uervirojnangkoorn, Monarin; University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck; Hilgenfeld, Rolf, E-mail: hilgenfeld@biochem.uni-luebeck.de

    A genetic algorithm has been developed to optimize the phases of the strongest reflections in SIR/SAD data. This is shown to facilitate density modification and model building in several test cases. Experimental phasing of diffraction data from macromolecular crystals involves deriving phase probability distributions. These distributions are often bimodal, making their weighted average, the centroid phase, improbable, so that electron-density maps computed using centroid phases are often non-interpretable. Density modification brings in information about the characteristics of electron density in protein crystals. In successful cases, this allows a choice between the modes in the phase probability distributions, and the mapsmore » can cross the borderline between non-interpretable and interpretable. Based on the suggestions by Vekhter [Vekhter (2005 ▶), Acta Cryst. D61, 899–902], the impact of identifying optimized phases for a small number of strong reflections prior to the density-modification process was investigated while using the centroid phase as a starting point for the remaining reflections. A genetic algorithm was developed that optimizes the quality of such phases using the skewness of the density map as a target function. Phases optimized in this way are then used in density modification. In most of the tests, the resulting maps were of higher quality than maps generated from the original centroid phases. In one of the test cases, the new method sufficiently improved a marginal set of experimental SAD phases to enable successful map interpretation. A computer program, SISA, has been developed to apply this method for phase improvement in macromolecular crystallography.« less

  3. Multi objective genetic algorithm to optimize the local heat treatment of a hardenable aluminum alloy

    NASA Astrophysics Data System (ADS)

    Piccininni, A.; Palumbo, G.; Franco, A. Lo; Sorgente, D.; Tricarico, L.; Russello, G.

    2018-05-01

    The continuous research for lightweight components for transport applications to reduce the harmful emissions drives the attention to the light alloys as in the case of Aluminium (Al) alloys, capable to combine low density with high values of the strength-to-weight ratio. Such advantages are partially counterbalanced by the poor formability at room temperature. A viable solution is to adopt a localized heat treatment by laser of the blank before the forming process to obtain a tailored distribution of material properties so that the blank can be formed at room temperature by means of conventional press machines. Such an approach has been extensively investigated for age hardenable alloys, but in the present work the attention is focused on the 5000 series; in particular, the optimization of the deep drawing process of the alloy AA5754 H32 is proposed through a numerical/experimental approach. A preliminary investigation was necessary to correctly tune the laser parameters (focus length, spot dimension) to effectively obtain the annealed state. Optimal process parameters were then obtained coupling a 2D FE model with an optimization platform managed by a multi-objective genetic algorithm. The optimal solution (i.e. able to maximize the LDR) in terms of blankholder force and extent of the annealed region was thus evaluated and validated through experimental trials. A good matching between experimental and numerical results was found. The optimal solution allowed to obtain an LDR of the locally heat treated blank larger than the one of the material either in the wrought condition (H32) either in the annealed condition (H111).

  4. Modelling and validation of diffuse reflectance of the adult human head for fNIRS: scalp sub-layers definition

    NASA Astrophysics Data System (ADS)

    Herrera-Vega, Javier; Montero-Hernández, Samuel; Tachtsidis, Ilias; Treviño-Palacios, Carlos G.; Orihuela-Espina, Felipe

    2017-11-01

    Accurate estimation of brain haemodynamics parameters such as cerebral blood flow and volume as well as oxygen consumption i.e. metabolic rate of oxygen, with funcional near infrared spectroscopy (fNIRS) requires precise characterization of light propagation through head tissues. An anatomically realistic forward model of the human adult head with unprecedented detailed specification of the 5 scalp sublayers to account for blood irrigation in the connective tissue layer is introduced. The full model consists of 9 layers, accounts for optical properties ranging from 750nm to 950nm and has a voxel size of 0.5mm. The whole model is validated comparing the predicted remitted spectra, using Monte Carlo simulations of radiation propagation with 108 photons, against continuous wave (CW) broadband fNIRS experimental data. As the true oxy- and deoxy-hemoglobin concentrations during acquisition are unknown, a genetic algorithm searched for the vector of parameters that generates a modelled spectrum that optimally fits the experimental spectrum. Differences between experimental and model predicted spectra was quantified using the Root mean square error (RMSE). RMSE was 0.071 +/- 0.004, 0.108 +/- 0.018 and 0.235+/-0.015 at 1, 2 and 3cm interoptode distance respectively. The parameter vector of absolute concentrations of haemoglobin species in scalp and cortex retrieved with the genetic algorithm was within histologically plausible ranges. The new model capability to estimate the contribution of the scalp blood flow shall permit incorporating this information to the regularization of the inverse problem for a cleaner reconstruction of brain hemodynamics.

  5. Performance Analysis of Combined Methods of Genetic Algorithm and K-Means Clustering in Determining the Value of Centroid

    NASA Astrophysics Data System (ADS)

    Adya Zizwan, Putra; Zarlis, Muhammad; Budhiarti Nababan, Erna

    2017-12-01

    The determination of Centroid on K-Means Algorithm directly affects the quality of the clustering results. Determination of centroid by using random numbers has many weaknesses. The GenClust algorithm that combines the use of Genetic Algorithms and K-Means uses a genetic algorithm to determine the centroid of each cluster. The use of the GenClust algorithm uses 50% chromosomes obtained through deterministic calculations and 50% is obtained from the generation of random numbers. This study will modify the use of the GenClust algorithm in which the chromosomes used are 100% obtained through deterministic calculations. The results of this study resulted in performance comparisons expressed in Mean Square Error influenced by centroid determination on K-Means method by using GenClust method, modified GenClust method and also classic K-Means.

  6. Application of a single-objective, hybrid genetic algorithm approach to pharmacokinetic model building.

    PubMed

    Sherer, Eric A; Sale, Mark E; Pollock, Bruce G; Belani, Chandra P; Egorin, Merrill J; Ivy, Percy S; Lieberman, Jeffrey A; Manuck, Stephen B; Marder, Stephen R; Muldoon, Matthew F; Scher, Howard I; Solit, David B; Bies, Robert R

    2012-08-01

    A limitation in traditional stepwise population pharmacokinetic model building is the difficulty in handling interactions between model components. To address this issue, a method was previously introduced which couples NONMEM parameter estimation and model fitness evaluation to a single-objective, hybrid genetic algorithm for global optimization of the model structure. In this study, the generalizability of this approach for pharmacokinetic model building is evaluated by comparing (1) correct and spurious covariate relationships in a simulated dataset resulting from automated stepwise covariate modeling, Lasso methods, and single-objective hybrid genetic algorithm approaches to covariate identification and (2) information criteria values, model structures, convergence, and model parameter values resulting from manual stepwise versus single-objective, hybrid genetic algorithm approaches to model building for seven compounds. Both manual stepwise and single-objective, hybrid genetic algorithm approaches to model building were applied, blinded to the results of the other approach, for selection of the compartment structure as well as inclusion and model form of inter-individual and inter-occasion variability, residual error, and covariates from a common set of model options. For the simulated dataset, stepwise covariate modeling identified three of four true covariates and two spurious covariates; Lasso identified two of four true and 0 spurious covariates; and the single-objective, hybrid genetic algorithm identified three of four true covariates and one spurious covariate. For the clinical datasets, the Akaike information criterion was a median of 22.3 points lower (range of 470.5 point decrease to 0.1 point decrease) for the best single-objective hybrid genetic-algorithm candidate model versus the final manual stepwise model: the Akaike information criterion was lower by greater than 10 points for four compounds and differed by less than 10 points for three compounds. The root mean squared error and absolute mean prediction error of the best single-objective hybrid genetic algorithm candidates were a median of 0.2 points higher (range of 38.9 point decrease to 27.3 point increase) and 0.02 points lower (range of 0.98 point decrease to 0.74 point increase), respectively, than that of the final stepwise models. In addition, the best single-objective, hybrid genetic algorithm candidate models had successful convergence and covariance steps for each compound, used the same compartment structure as the manual stepwise approach for 6 of 7 (86 %) compounds, and identified 54 % (7 of 13) of covariates included by the manual stepwise approach and 16 covariate relationships not included by manual stepwise models. The model parameter values between the final manual stepwise and best single-objective, hybrid genetic algorithm models differed by a median of 26.7 % (q₁ = 4.9 % and q₃ = 57.1 %). Finally, the single-objective, hybrid genetic algorithm approach was able to identify models capable of estimating absorption rate parameters for four compounds that the manual stepwise approach did not identify. The single-objective, hybrid genetic algorithm represents a general pharmacokinetic model building methodology whose ability to rapidly search the feasible solution space leads to nearly equivalent or superior model fits to pharmacokinetic data.

  7. The alliance relationship analysis of international terrorist organizations with link prediction

    NASA Astrophysics Data System (ADS)

    Fang, Ling; Fang, Haiyang; Tian, Yanfang; Yang, Tinghong; Zhao, Jing

    2017-09-01

    Terrorism is a huge public hazard of the international community. Alliances of terrorist organizations may cause more serious threat to national security and world peace. Understanding alliances between global terrorist organizations will facilitate more effective anti-terrorism collaboration between governments. Based on publicly available data, this study constructed a alliance network between terrorist organizations and analyzed the alliance relationships with link prediction. We proposed a novel index based on optimal weighted fusion of six similarity indices, in which the optimal weight is calculated by genetic algorithm. Our experimental results showed that this algorithm could achieve better results on the networks than other algorithms. Using this method, we successfully digged out 21 real terrorist organizations alliance from current data. Our experiment shows that this approach used for terrorist organizations alliance mining is effective and this study is expected to benefit the form of a more powerful anti-terrorism strategy.

  8. Memetic algorithms for de novo motif-finding in biomedical sequences.

    PubMed

    Bi, Chengpeng

    2012-09-01

    The objectives of this study are to design and implement a new memetic algorithm for de novo motif discovery, which is then applied to detect important signals hidden in various biomedical molecular sequences. In this paper, memetic algorithms are developed and tested in de novo motif-finding problems. Several strategies in the algorithm design are employed that are to not only efficiently explore the multiple sequence local alignment space, but also effectively uncover the molecular signals. As a result, there are a number of key features in the implementation of the memetic motif-finding algorithm (MaMotif), including a chromosome replacement operator, a chromosome alteration-aware local search operator, a truncated local search strategy, and a stochastic operation of local search imposed on individual learning. To test the new algorithm, we compare MaMotif with a few of other similar algorithms using simulated and experimental data including genomic DNA, primary microRNA sequences (let-7 family), and transmembrane protein sequences. The new memetic motif-finding algorithm is successfully implemented in C++, and exhaustively tested with various simulated and real biological sequences. In the simulation, it shows that MaMotif is the most time-efficient algorithm compared with others, that is, it runs 2 times faster than the expectation maximization (EM) method and 16 times faster than the genetic algorithm-based EM hybrid. In both simulated and experimental testing, results show that the new algorithm is compared favorably or superior to other algorithms. Notably, MaMotif is able to successfully discover the transcription factors' binding sites in the chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-Seq) data, correctly uncover the RNA splicing signals in gene expression, and precisely find the highly conserved helix motif in the transmembrane protein sequences, as well as rightly detect the palindromic segments in the primary microRNA sequences. The memetic motif-finding algorithm is effectively designed and implemented, and its applications demonstrate it is not only time-efficient, but also exhibits excellent performance while compared with other popular algorithms. Copyright © 2012 Elsevier B.V. All rights reserved.

  9. mRMR-ABC: A Hybrid Gene Selection Algorithm for Cancer Classification Using Microarray Gene Expression Profiling

    PubMed Central

    Alshamlan, Hala; Badr, Ghada; Alohali, Yousef

    2015-01-01

    An artificial bee colony (ABC) is a relatively recent swarm intelligence optimization approach. In this paper, we propose the first attempt at applying ABC algorithm in analyzing a microarray gene expression profile. In addition, we propose an innovative feature selection algorithm, minimum redundancy maximum relevance (mRMR), and combine it with an ABC algorithm, mRMR-ABC, to select informative genes from microarray profile. The new approach is based on a support vector machine (SVM) algorithm to measure the classification accuracy for selected genes. We evaluate the performance of the proposed mRMR-ABC algorithm by conducting extensive experiments on six binary and multiclass gene expression microarray datasets. Furthermore, we compare our proposed mRMR-ABC algorithm with previously known techniques. We reimplemented two of these techniques for the sake of a fair comparison using the same parameters. These two techniques are mRMR when combined with a genetic algorithm (mRMR-GA) and mRMR when combined with a particle swarm optimization algorithm (mRMR-PSO). The experimental results prove that the proposed mRMR-ABC algorithm achieves accurate classification performance using small number of predictive genes when tested using both datasets and compared to previously suggested methods. This shows that mRMR-ABC is a promising approach for solving gene selection and cancer classification problems. PMID:25961028

  10. mRMR-ABC: A Hybrid Gene Selection Algorithm for Cancer Classification Using Microarray Gene Expression Profiling.

    PubMed

    Alshamlan, Hala; Badr, Ghada; Alohali, Yousef

    2015-01-01

    An artificial bee colony (ABC) is a relatively recent swarm intelligence optimization approach. In this paper, we propose the first attempt at applying ABC algorithm in analyzing a microarray gene expression profile. In addition, we propose an innovative feature selection algorithm, minimum redundancy maximum relevance (mRMR), and combine it with an ABC algorithm, mRMR-ABC, to select informative genes from microarray profile. The new approach is based on a support vector machine (SVM) algorithm to measure the classification accuracy for selected genes. We evaluate the performance of the proposed mRMR-ABC algorithm by conducting extensive experiments on six binary and multiclass gene expression microarray datasets. Furthermore, we compare our proposed mRMR-ABC algorithm with previously known techniques. We reimplemented two of these techniques for the sake of a fair comparison using the same parameters. These two techniques are mRMR when combined with a genetic algorithm (mRMR-GA) and mRMR when combined with a particle swarm optimization algorithm (mRMR-PSO). The experimental results prove that the proposed mRMR-ABC algorithm achieves accurate classification performance using small number of predictive genes when tested using both datasets and compared to previously suggested methods. This shows that mRMR-ABC is a promising approach for solving gene selection and cancer classification problems.

  11. All-Dielectric Multilayer Cylindrical Structures for Invisibility Cloaking

    PubMed Central

    Mirzaei, Ali; Miroshnichenko, Andrey E.; Shadrivov, Ilya V.; Kivshar, Yuri S.

    2015-01-01

    We study optical response of all-dielectric multilayer structures and demonstrate that the total scattering of such structures can be suppressed leading to optimal invisibility cloaking. We use experimental material data and a genetic algorithm to reduce the total scattering by adjusting the material and thickness of various layers for several types of dielectric cores at telecommunication wavelengths. Our approach demonstrates 80-fold suppression of the total scattering cross-section by employing just a few dielectric layers. PMID:25858295

  12. Optimal sensor placement for time-domain identification using a wavelet-based genetic algorithm

    NASA Astrophysics Data System (ADS)

    Mahdavi, Seyed Hossein; Razak, Hashim Abdul

    2016-06-01

    This paper presents a wavelet-based genetic algorithm strategy for optimal sensor placement (OSP) effective for time-domain structural identification. Initially, the GA-based fitness evaluation is significantly improved by using adaptive wavelet functions. Later, a multi-species decimal GA coding system is modified to be suitable for an efficient search around the local optima. In this regard, a local operation of mutation is introduced in addition with regeneration and reintroduction operators. It is concluded that different characteristics of applied force influence the features of structural responses, and therefore the accuracy of time-domain structural identification is directly affected. Thus, the reliable OSP strategy prior to the time-domain identification will be achieved by those methods dealing with minimizing the distance of simulated responses for the entire system and condensed system considering the force effects. The numerical and experimental verification on the effectiveness of the proposed strategy demonstrates the considerably high computational performance of the proposed OSP strategy, in terms of computational cost and the accuracy of identification. It is deduced that the robustness of the proposed OSP algorithm lies in the precise and fast fitness evaluation at larger sampling rates which result in the optimum evaluation of the GA-based exploration and exploitation phases towards the global optimum solution.

  13. Gene selection for microarray cancer classification using a new evolutionary method employing artificial intelligence concepts.

    PubMed

    Dashtban, M; Balafar, Mohammadali

    2017-03-01

    Gene selection is a demanding task for microarray data analysis. The diverse complexity of different cancers makes this issue still challenging. In this study, a novel evolutionary method based on genetic algorithms and artificial intelligence is proposed to identify predictive genes for cancer classification. A filter method was first applied to reduce the dimensionality of feature space followed by employing an integer-coded genetic algorithm with dynamic-length genotype, intelligent parameter settings, and modified operators. The algorithmic behaviors including convergence trends, mutation and crossover rate changes, and running time were studied, conceptually discussed, and shown to be coherent with literature findings. Two well-known filter methods, Laplacian and Fisher score, were examined considering similarities, the quality of selected genes, and their influences on the evolutionary approach. Several statistical tests concerning choice of classifier, choice of dataset, and choice of filter method were performed, and they revealed some significant differences between the performance of different classifiers and filter methods over datasets. The proposed method was benchmarked upon five popular high-dimensional cancer datasets; for each, top explored genes were reported. Comparing the experimental results with several state-of-the-art methods revealed that the proposed method outperforms previous methods in DLBCL dataset. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Offspring Generation Method for interactive Genetic Algorithm considering Multimodal Preference

    NASA Astrophysics Data System (ADS)

    Ito, Fuyuko; Hiroyasu, Tomoyuki; Miki, Mitsunori; Yokouchi, Hisatake

    In interactive genetic algorithms (iGAs), computer simulations prepare design candidates that are then evaluated by the user. Therefore, iGA can predict a user's preferences. Conventional iGA problems involve a search for a single optimum solution, and iGA were developed to find this single optimum. On the other hand, our target problems have several peaks in a function and there are small differences among these peaks. For such problems, it is better to show all the peaks to the user. Product recommendation in shopping sites on the web is one example of such problems. Several types of preference trend should be prepared for users in shopping sites. Exploitation and exploration are important mechanisms in GA search. To perform effective exploitation, the offspring generation method (crossover) is very important. Here, we introduced a new offspring generation method for iGA in multimodal problems. In the proposed method, individuals are clustered into subgroups and offspring are generated in each group. The proposed method was applied to an experimental iGA system to examine its effectiveness. In the experimental iGA system, users can decide on preferable t-shirts to buy. The results of the subjective experiment confirmed that the proposed method enables offspring generation with consideration of multimodal preferences, and the proposed mechanism was also shown not to adversely affect the performance of preference prediction.

  15. Cloud computing-based TagSNP selection algorithm for human genome data.

    PubMed

    Hung, Che-Lun; Chen, Wen-Pei; Hua, Guan-Jie; Zheng, Huiru; Tsai, Suh-Jen Jane; Lin, Yaw-Ling

    2015-01-05

    Single nucleotide polymorphisms (SNPs) play a fundamental role in human genetic variation and are used in medical diagnostics, phylogeny construction, and drug design. They provide the highest-resolution genetic fingerprint for identifying disease associations and human features. Haplotypes are regions of linked genetic variants that are closely spaced on the genome and tend to be inherited together. Genetics research has revealed SNPs within certain haplotype blocks that introduce few distinct common haplotypes into most of the population. Haplotype block structures are used in association-based methods to map disease genes. In this paper, we propose an efficient algorithm for identifying haplotype blocks in the genome. In chromosomal haplotype data retrieved from the HapMap project website, the proposed algorithm identified longer haplotype blocks than an existing algorithm. To enhance its performance, we extended the proposed algorithm into a parallel algorithm that copies data in parallel via the Hadoop MapReduce framework. The proposed MapReduce-paralleled combinatorial algorithm performed well on real-world data obtained from the HapMap dataset; the improvement in computational efficiency was proportional to the number of processors used.

  16. The Applications of Genetic Algorithms in Medicine.

    PubMed

    Ghaheri, Ali; Shoar, Saeed; Naderan, Mohammad; Hoseini, Sayed Shahabuddin

    2015-11-01

    A great wealth of information is hidden amid medical research data that in some cases cannot be easily analyzed, if at all, using classical statistical methods. Inspired by nature, metaheuristic algorithms have been developed to offer optimal or near-optimal solutions to complex data analysis and decision-making tasks in a reasonable time. Due to their powerful features, metaheuristic algorithms have frequently been used in other fields of sciences. In medicine, however, the use of these algorithms are not known by physicians who may well benefit by applying them to solve complex medical problems. Therefore, in this paper, we introduce the genetic algorithm and its applications in medicine. The use of the genetic algorithm has promising implications in various medical specialties including radiology, radiotherapy, oncology, pediatrics, cardiology, endocrinology, surgery, obstetrics and gynecology, pulmonology, infectious diseases, orthopedics, rehabilitation medicine, neurology, pharmacotherapy, and health care management. This review introduces the applications of the genetic algorithm in disease screening, diagnosis, treatment planning, pharmacovigilance, prognosis, and health care management, and enables physicians to envision possible applications of this metaheuristic method in their medical career.].

  17. The Applications of Genetic Algorithms in Medicine

    PubMed Central

    Ghaheri, Ali; Shoar, Saeed; Naderan, Mohammad; Hoseini, Sayed Shahabuddin

    2015-01-01

    A great wealth of information is hidden amid medical research data that in some cases cannot be easily analyzed, if at all, using classical statistical methods. Inspired by nature, metaheuristic algorithms have been developed to offer optimal or near-optimal solutions to complex data analysis and decision-making tasks in a reasonable time. Due to their powerful features, metaheuristic algorithms have frequently been used in other fields of sciences. In medicine, however, the use of these algorithms are not known by physicians who may well benefit by applying them to solve complex medical problems. Therefore, in this paper, we introduce the genetic algorithm and its applications in medicine. The use of the genetic algorithm has promising implications in various medical specialties including radiology, radiotherapy, oncology, pediatrics, cardiology, endocrinology, surgery, obstetrics and gynecology, pulmonology, infectious diseases, orthopedics, rehabilitation medicine, neurology, pharmacotherapy, and health care management. This review introduces the applications of the genetic algorithm in disease screening, diagnosis, treatment planning, pharmacovigilance, prognosis, and health care management, and enables physicians to envision possible applications of this metaheuristic method in their medical career.] PMID:26676060

  18. Cloud Computing-Based TagSNP Selection Algorithm for Human Genome Data

    PubMed Central

    Hung, Che-Lun; Chen, Wen-Pei; Hua, Guan-Jie; Zheng, Huiru; Tsai, Suh-Jen Jane; Lin, Yaw-Ling

    2015-01-01

    Single nucleotide polymorphisms (SNPs) play a fundamental role in human genetic variation and are used in medical diagnostics, phylogeny construction, and drug design. They provide the highest-resolution genetic fingerprint for identifying disease associations and human features. Haplotypes are regions of linked genetic variants that are closely spaced on the genome and tend to be inherited together. Genetics research has revealed SNPs within certain haplotype blocks that introduce few distinct common haplotypes into most of the population. Haplotype block structures are used in association-based methods to map disease genes. In this paper, we propose an efficient algorithm for identifying haplotype blocks in the genome. In chromosomal haplotype data retrieved from the HapMap project website, the proposed algorithm identified longer haplotype blocks than an existing algorithm. To enhance its performance, we extended the proposed algorithm into a parallel algorithm that copies data in parallel via the Hadoop MapReduce framework. The proposed MapReduce-paralleled combinatorial algorithm performed well on real-world data obtained from the HapMap dataset; the improvement in computational efficiency was proportional to the number of processors used. PMID:25569088

  19. Evaluation of Genetic Algorithm Concepts Using Model Problems. Part 2; Multi-Objective Optimization

    NASA Technical Reports Server (NTRS)

    Holst, Terry L.; Pulliam, Thomas H.

    2003-01-01

    A genetic algorithm approach suitable for solving multi-objective optimization problems is described and evaluated using a series of simple model problems. Several new features including a binning selection algorithm and a gene-space transformation procedure are included. The genetic algorithm is suitable for finding pareto optimal solutions in search spaces that are defined by any number of genes and that contain any number of local extrema. Results indicate that the genetic algorithm optimization approach is flexible in application and extremely reliable, providing optimal results for all optimization problems attempted. The binning algorithm generally provides pareto front quality enhancements and moderate convergence efficiency improvements for most of the model problems. The gene-space transformation procedure provides a large convergence efficiency enhancement for problems with non-convoluted pareto fronts and a degradation in efficiency for problems with convoluted pareto fronts. The most difficult problems --multi-mode search spaces with a large number of genes and convoluted pareto fronts-- require a large number of function evaluations for GA convergence, but always converge.

  20. A genetic algorithm for replica server placement

    NASA Astrophysics Data System (ADS)

    Eslami, Ghazaleh; Toroghi Haghighat, Abolfazl

    2012-01-01

    Modern distribution systems use replication to improve communication delay experienced by their clients. Some techniques have been developed for web server replica placement. One of the previous studies was Greedy algorithm proposed by Qiu et al, that needs knowledge about network topology. In This paper, first we introduce a genetic algorithm for web server replica placement. Second, we compare our algorithm with Greedy algorithm proposed by Qiu et al, and Optimum algorithm. We found that our approach can achieve better results than Greedy algorithm proposed by Qiu et al but it's computational time is more than Greedy algorithm.

  1. A genetic algorithm for replica server placement

    NASA Astrophysics Data System (ADS)

    Eslami, Ghazaleh; Toroghi Haghighat, Abolfazl

    2011-12-01

    Modern distribution systems use replication to improve communication delay experienced by their clients. Some techniques have been developed for web server replica placement. One of the previous studies was Greedy algorithm proposed by Qiu et al, that needs knowledge about network topology. In This paper, first we introduce a genetic algorithm for web server replica placement. Second, we compare our algorithm with Greedy algorithm proposed by Qiu et al, and Optimum algorithm. We found that our approach can achieve better results than Greedy algorithm proposed by Qiu et al but it's computational time is more than Greedy algorithm.

  2. Multiobjective optimisation design for enterprise system operation in the case of scheduling problem with deteriorating jobs

    NASA Astrophysics Data System (ADS)

    Wang, Hongfeng; Fu, Yaping; Huang, Min; Wang, Junwei

    2016-03-01

    The operation process design is one of the key issues in the manufacturing and service sectors. As a typical operation process, the scheduling with consideration of the deteriorating effect has been widely studied; however, the current literature only studied single function requirement and rarely considered the multiple function requirements which are critical for a real-world scheduling process. In this article, two function requirements are involved in the design of a scheduling process with consideration of the deteriorating effect and then formulated into two objectives of a mathematical programming model. A novel multiobjective evolutionary algorithm is proposed to solve this model with combination of three strategies, i.e. a multiple population scheme, a rule-based local search method and an elitist preserve strategy. To validate the proposed model and algorithm, a series of randomly-generated instances are tested and the experimental results indicate that the model is effective and the proposed algorithm can achieve the satisfactory performance which outperforms the other state-of-the-art multiobjective evolutionary algorithms, such as nondominated sorting genetic algorithm II and multiobjective evolutionary algorithm based on decomposition, on all the test instances.

  3. Chaotic particle swarm optimization with mutation for classification.

    PubMed

    Assarzadeh, Zahra; Naghsh-Nilchi, Ahmad Reza

    2015-01-01

    In this paper, a chaotic particle swarm optimization with mutation-based classifier particle swarm optimization is proposed to classify patterns of different classes in the feature space. The introduced mutation operators and chaotic sequences allows us to overcome the problem of early convergence into a local minima associated with particle swarm optimization algorithms. That is, the mutation operator sharpens the convergence and it tunes the best possible solution. Furthermore, to remove the irrelevant data and reduce the dimensionality of medical datasets, a feature selection approach using binary version of the proposed particle swarm optimization is introduced. In order to demonstrate the effectiveness of our proposed classifier, mutation-based classifier particle swarm optimization, it is checked out with three sets of data classifications namely, Wisconsin diagnostic breast cancer, Wisconsin breast cancer and heart-statlog, with different feature vector dimensions. The proposed algorithm is compared with different classifier algorithms including k-nearest neighbor, as a conventional classifier, particle swarm-classifier, genetic algorithm, and Imperialist competitive algorithm-classifier, as more sophisticated ones. The performance of each classifier was evaluated by calculating the accuracy, sensitivity, specificity and Matthews's correlation coefficient. The experimental results show that the mutation-based classifier particle swarm optimization unequivocally performs better than all the compared algorithms.

  4. Comparison of optimization algorithms in intensity-modulated radiation therapy planning

    NASA Astrophysics Data System (ADS)

    Kendrick, Rachel

    Intensity-modulated radiation therapy is used to better conform the radiation dose to the target, which includes avoiding healthy tissue. Planning programs employ optimization methods to search for the best fluence of each photon beam, and therefore to create the best treatment plan. The Computational Environment for Radiotherapy Research (CERR), a program written in MATLAB, was used to examine some commonly-used algorithms for one 5-beam plan. Algorithms include the genetic algorithm, quadratic programming, pattern search, constrained nonlinear optimization, simulated annealing, the optimization method used in Varian EclipseTM, and some hybrids of these. Quadratic programing, simulated annealing, and a quadratic/simulated annealing hybrid were also separately compared using different prescription doses. The results of each dose-volume histogram as well as the visual dose color wash were used to compare the plans. CERR's built-in quadratic programming provided the best overall plan, but avoidance of the organ-at-risk was rivaled by other programs. Hybrids of quadratic programming with some of these algorithms seems to suggest the possibility of better planning programs, as shown by the improved quadratic/simulated annealing plan when compared to the simulated annealing algorithm alone. Further experimentation will be done to improve cost functions and computational time.

  5. MIP models and hybrid algorithms for simultaneous job splitting and scheduling on unrelated parallel machines.

    PubMed

    Eroglu, Duygu Yilmaz; Ozmutlu, H Cenk

    2014-01-01

    We developed mixed integer programming (MIP) models and hybrid genetic-local search algorithms for the scheduling problem of unrelated parallel machines with job sequence and machine-dependent setup times and with job splitting property. The first contribution of this paper is to introduce novel algorithms which make splitting and scheduling simultaneously with variable number of subjobs. We proposed simple chromosome structure which is constituted by random key numbers in hybrid genetic-local search algorithm (GAspLA). Random key numbers are used frequently in genetic algorithms, but it creates additional difficulty when hybrid factors in local search are implemented. We developed algorithms that satisfy the adaptation of results of local search into the genetic algorithms with minimum relocation operation of genes' random key numbers. This is the second contribution of the paper. The third contribution of this paper is three developed new MIP models which are making splitting and scheduling simultaneously. The fourth contribution of this paper is implementation of the GAspLAMIP. This implementation let us verify the optimality of GAspLA for the studied combinations. The proposed methods are tested on a set of problems taken from the literature and the results validate the effectiveness of the proposed algorithms.

  6. Truss Optimization for a Manned Nuclear Electric Space Vehicle using Genetic Algorithms

    NASA Technical Reports Server (NTRS)

    Benford, Andrew; Tinker, Michael L.

    2004-01-01

    The purpose of this paper is to utilize the genetic algorithm (GA) optimization method for structural design of a nuclear propulsion vehicle. Genetic algorithms provide a guided, random search technique that mirrors biological adaptation. To verify the GA capabilities, other traditional optimization methods were used to generate results for comparison to the GA results, first for simple two-dimensional structures, and then for full-scale three-dimensional truss designs.

  7. A High Fuel Consumption Efficiency Management Scheme for PHEVs Using an Adaptive Genetic Algorithm

    PubMed Central

    Lee, Wah Ching; Tsang, Kim Fung; Chi, Hao Ran; Hung, Faan Hei; Wu, Chung Kit; Chui, Kwok Tai; Lau, Wing Hong; Leung, Yat Wah

    2015-01-01

    A high fuel efficiency management scheme for plug-in hybrid electric vehicles (PHEVs) has been developed. In order to achieve fuel consumption reduction, an adaptive genetic algorithm scheme has been designed to adaptively manage the energy resource usage. The objective function of the genetic algorithm is implemented by designing a fuzzy logic controller which closely monitors and resembles the driving conditions and environment of PHEVs, thus trading off between petrol versus electricity for optimal driving efficiency. Comparison between calculated results and publicized data shows that the achieved efficiency of the fuzzified genetic algorithm is better by 10% than existing schemes. The developed scheme, if fully adopted, would help reduce over 600 tons of CO2 emissions worldwide every day. PMID:25587974

  8. Neural-network-assisted genetic algorithm applied to silicon clusters

    NASA Astrophysics Data System (ADS)

    Marim, L. R.; Lemes, M. R.; dal Pino, A.

    2003-03-01

    Recently, a new optimization procedure that combines the power of artificial neural-networks with the versatility of the genetic algorithm (GA) was introduced. This method, called neural-network-assisted genetic algorithm (NAGA), uses a neural network to restrict the search space and it is expected to speed up the solution of global optimization problems if some previous information is available. In this paper, we have tested NAGA to determine the ground-state geometry of Sin (10⩽n⩽15) according to a tight-binding total-energy method. Our results indicate that NAGA was able to find the desired global minimum of the potential energy for all the test cases and it was at least ten times faster than pure genetic algorithm.

  9. Multiple Query Evaluation Based on an Enhanced Genetic Algorithm.

    ERIC Educational Resources Information Center

    Tamine, Lynda; Chrisment, Claude; Boughanem, Mohand

    2003-01-01

    Explains the use of genetic algorithms to combine results from multiple query evaluations to improve relevance in information retrieval. Discusses niching techniques, relevance feedback techniques, and evolution heuristics, and compares retrieval results obtained by both genetic multiple query evaluation and classical single query evaluation…

  10. MOESHA: A genetic algorithm for automatic calibration and estimation of parameter uncertainty and sensitivity of hydrologic models

    EPA Science Inventory

    Characterization of uncertainty and sensitivity of model parameters is an essential and often overlooked facet of hydrological modeling. This paper introduces an algorithm called MOESHA that combines input parameter sensitivity analyses with a genetic algorithm calibration routin...

  11. Approximation of properties of hyperelastic materials with use of energy-based models and biaxial tension data

    NASA Astrophysics Data System (ADS)

    Jamróz, Weronika

    2016-06-01

    The paper shows the way enrgy-based models aproximate mechanical properties of hiperelastic materials. Main goal of research was to create a method of finding a set of material constants that are included in a strain energy function that constitutes a heart of an energy-based model. The most optimal set of material constants determines the best adjustment of a theoretical stress-strain relation to the experimental one. This kind of adjustment enables better prediction of behaviour of a chosen material. In order to obtain more precised solution the approximation was made with use of data obtained in a modern experiment widely describen in [1]. To save computation time main algorithm is based on genetic algorithms.

  12. Genetic algorithm prediction of two-dimensional group-IV dioxides for dielectrics

    NASA Astrophysics Data System (ADS)

    Singh, Arunima K.; Revard, Benjamin C.; Ramanathan, Rohit; Ashton, Michael; Tavazza, Francesca; Hennig, Richard G.

    2017-04-01

    Two-dimensional (2D) materials present a new class of materials whose structures and properties can differ from their bulk counterparts. We perform a genetic algorithm structure search using density-functional theory to identify low-energy structures of 2D group-IV dioxides A O2 (A =Si , Ge, Sn, Pb). We find that 2D SiO2 is most stable in the experimentally determined bi-tetrahedral structure, while 2D SnO2 and PbO2 are most stable in the 1 T structure. For 2D GeO2, the genetic algorithm finds a new low-energy 2D structure with monoclinic symmetry. Each system exhibits 2D structures with formation energies ranging from 26 to 151 meV/atom, below those of certain already synthesized 2D materials. The phonon spectra confirm their dynamic stability. Using the HSE06 hybrid functional, we determine that the 2D dioxides are insulators or semiconductors, with a direct band gap of 7.2 eV at Γ for 2D SiO2, and indirect band gaps of 4.8-2.7 eV for the other dioxides. To guide future applications of these 2D materials in nanoelectronic devices, we determine their band-edge alignment with graphene, phosphorene, and single-layer BN and MoS2. An assessment of the dielectric properties and electrochemical stability of the 2D group-IV dioxides shows that 2D GeO2 and SnO2 are particularly promising candidates for gate oxides and 2D SnO2 also as a protective layer in heterostructure nanoelectronic devices.

  13. A genetic algorithm for solving supply chain network design model

    NASA Astrophysics Data System (ADS)

    Firoozi, Z.; Ismail, N.; Ariafar, S. H.; Tang, S. H.; Ariffin, M. K. M. A.

    2013-09-01

    Network design is by nature costly and optimization models play significant role in reducing the unnecessary cost components of a distribution network. This study proposes a genetic algorithm to solve a distribution network design model. The structure of the chromosome in the proposed algorithm is defined in a novel way that in addition to producing feasible solutions, it also reduces the computational complexity of the algorithm. Computational results are presented to show the algorithm performance.

  14. The simulation method of chemical composition of vermicular graphite iron on the basis of genetic algorithm

    NASA Astrophysics Data System (ADS)

    Yusupov, L. R.; Klochkova, K. V.; Simonova, L. A.

    2017-09-01

    The paper presents a methodology of modeling the chemical composition of the composite material via genetic algorithm for optimization of the manufacturing process of products. The paper presents algorithms of methods based on intelligent system of vermicular graphite iron design

  15. MULTI-OBJECTIVE OPTIMAL DESIGN OF GROUNDWATER REMEDIATION SYSTEMS: APPLICATION OF THE NICHED PARETO GENETIC ALGORITHM (NPGA). (R826614)

    EPA Science Inventory

    A multiobjective optimization algorithm is applied to a groundwater quality management problem involving remediation by pump-and-treat (PAT). The multiobjective optimization framework uses the niched Pareto genetic algorithm (NPGA) and is applied to simultaneously minimize the...

  16. Multi-Objective Constraint Satisfaction for Mobile Robot Area Defense

    DTIC Science & Technology

    2010-03-01

    17 NSGA-II non-dominated sorting genetic algorithm II . . . . . . . . . . . . . . . . . . . 17 jMetal Metaheuristic Algorithms in...to alert the other agents and ensure trust in the system. This research presents an algorithm that tasks robots to meet the two specific goals of...problem is defined as a constraint satisfaction problem solved using the Non-dominated Sorting Genetic Algorithm II (NSGA-II). Both goals of

  17. Application of genetic algorithm in modeling on-wafer inductors for up to 110 Ghz

    NASA Astrophysics Data System (ADS)

    Liu, Nianhong; Fu, Jun; Liu, Hui; Cui, Wenpu; Liu, Zhihong; Liu, Linlin; Zhou, Wei; Wang, Quan; Guo, Ao

    2018-05-01

    In this work, the genetic algorithm has been introducted into parameter extraction for on-wafer inductors for up to 110 GHz millimeter-wave operations, and nine independent parameters of the equivalent circuit model are optimized together. With the genetic algorithm, the model with the optimized parameters gives a better fitting accuracy than the preliminary parameters without optimization. Especially, the fitting accuracy of the Q value achieves a significant improvement after the optimization.

  18. Combinatorial Multiobjective Optimization Using Genetic Algorithms

    NASA Technical Reports Server (NTRS)

    Crossley, William A.; Martin. Eric T.

    2002-01-01

    The research proposed in this document investigated multiobjective optimization approaches based upon the Genetic Algorithm (GA). Several versions of the GA have been adopted for multiobjective design, but, prior to this research, there had not been significant comparisons of the most popular strategies. The research effort first generalized the two-branch tournament genetic algorithm in to an N-branch genetic algorithm, then the N-branch GA was compared with a version of the popular Multi-Objective Genetic Algorithm (MOGA). Because the genetic algorithm is well suited to combinatorial (mixed discrete / continuous) optimization problems, the GA can be used in the conceptual phase of design to combine selection (discrete variable) and sizing (continuous variable) tasks. Using a multiobjective formulation for the design of a 50-passenger aircraft to meet the competing objectives of minimizing takeoff gross weight and minimizing trip time, the GA generated a range of tradeoff designs that illustrate which aircraft features change from a low-weight, slow trip-time aircraft design to a heavy-weight, short trip-time aircraft design. Given the objective formulation and analysis methods used, the results of this study identify where turboprop-powered aircraft and turbofan-powered aircraft become more desirable for the 50 seat passenger application. This aircraft design application also begins to suggest how a combinatorial multiobjective optimization technique could be used to assist in the design of morphing aircraft.

  19. [Application of genetic algorithm in blending technology for extractions of Cortex Fraxini].

    PubMed

    Yang, Ming; Zhou, Yinmin; Chen, Jialei; Yu, Minying; Shi, Xiufeng; Gu, Xijun

    2009-10-01

    To explore the feasibility of genetic algorithm (GA) on multiple objective blending technology for extractions of Cortex Fraxini. According to that the optimization objective was the combination of fingerprint similarity and the root-mean-square error of multiple key constituents, a new multiple objective optimization model of 10 batches extractions of Cortex Fraxini was built. The blending coefficient was obtained by genetic algorithm. The quality of 10 batches extractions of Cortex Fraxini that after blending was evaluated with the finger print similarity and root-mean-square error as indexes. The quality of 10 batches extractions of Cortex Fraxini that after blending was well improved. Comparing with the fingerprint of the control sample, the similarity was up, but the degree of variation is down. The relative deviation of the key constituents was less than 10%. It is proved that genetic algorithm works well on multiple objective blending technology for extractions of Cortex Fraxini. This method can be a reference to control the quality of extractions of Cortex Fraxini. Genetic algorithm in blending technology for extractions of Chinese medicines is advisable.

  20. Improving Brain Magnetic Resonance Image (MRI) Segmentation via a Novel Algorithm based on Genetic and Regional Growth

    PubMed Central

    A., Javadpour; A., Mohammadi

    2016-01-01

    Background Regarding the importance of right diagnosis in medical applications, various methods have been exploited for processing medical images solar. The method of segmentation is used to analyze anal to miscall structures in medical imaging. Objective This study describes a new method for brain Magnetic Resonance Image (MRI) segmentation via a novel algorithm based on genetic and regional growth. Methods Among medical imaging methods, brains MRI segmentation is important due to high contrast of non-intrusive soft tissue and high spatial resolution. Size variations of brain tissues are often accompanied by various diseases such as Alzheimer’s disease. As our knowledge about the relation between various brain diseases and deviation of brain anatomy increases, MRI segmentation is exploited as the first step in early diagnosis. In this paper, regional growth method and auto-mate selection of initial points by genetic algorithm is used to introduce a new method for MRI segmentation. Primary pixels and similarity criterion are automatically by genetic algorithms to maximize the accuracy and validity in image segmentation. Results By using genetic algorithms and defining the fixed function of image segmentation, the initial points for the algorithm were found. The proposed algorithms are applied to the images and results are manually selected by regional growth in which the initial points were compared. The results showed that the proposed algorithm could reduce segmentation error effectively. Conclusion The study concluded that the proposed algorithm could reduce segmentation error effectively and help us to diagnose brain diseases. PMID:27672629

  1. Optimizing multiple sequence alignments using a genetic algorithm based on three objectives: structural information, non-gaps percentage and totally conserved columns.

    PubMed

    Ortuño, Francisco M; Valenzuela, Olga; Rojas, Fernando; Pomares, Hector; Florido, Javier P; Urquiza, Jose M; Rojas, Ignacio

    2013-09-01

    Multiple sequence alignments (MSAs) are widely used approaches in bioinformatics to carry out other tasks such as structure predictions, biological function analyses or phylogenetic modeling. However, current tools usually provide partially optimal alignments, as each one is focused on specific biological features. Thus, the same set of sequences can produce different alignments, above all when sequences are less similar. Consequently, researchers and biologists do not agree about which is the most suitable way to evaluate MSAs. Recent evaluations tend to use more complex scores including further biological features. Among them, 3D structures are increasingly being used to evaluate alignments. Because structures are more conserved in proteins than sequences, scores with structural information are better suited to evaluate more distant relationships between sequences. The proposed multiobjective algorithm, based on the non-dominated sorting genetic algorithm, aims to jointly optimize three objectives: STRIKE score, non-gaps percentage and totally conserved columns. It was significantly assessed on the BAliBASE benchmark according to the Kruskal-Wallis test (P < 0.01). This algorithm also outperforms other aligners, such as ClustalW, Multiple Sequence Alignment Genetic Algorithm (MSA-GA), PRRP, DIALIGN, Hidden Markov Model Training (HMMT), Pattern-Induced Multi-sequence Alignment (PIMA), MULTIALIGN, Sequence Alignment Genetic Algorithm (SAGA), PILEUP, Rubber Band Technique Genetic Algorithm (RBT-GA) and Vertical Decomposition Genetic Algorithm (VDGA), according to the Wilcoxon signed-rank test (P < 0.05), whereas it shows results not significantly different to 3D-COFFEE (P > 0.05) with the advantage of being able to use less structures. Structural information is included within the objective function to evaluate more accurately the obtained alignments. The source code is available at http://www.ugr.es/~fortuno/MOSAStrE/MO-SAStrE.zip.

  2. Feature Selection for Object-Based Classification of High-Resolution Remote Sensing Images Based on the Combination of a Genetic Algorithm and Tabu Search

    PubMed Central

    Shi, Lei; Wan, Youchuan; Gao, Xianjun

    2018-01-01

    In object-based image analysis of high-resolution images, the number of features can reach hundreds, so it is necessary to perform feature reduction prior to classification. In this paper, a feature selection method based on the combination of a genetic algorithm (GA) and tabu search (TS) is presented. The proposed GATS method aims to reduce the premature convergence of the GA by the use of TS. A prematurity index is first defined to judge the convergence situation during the search. When premature convergence does take place, an improved mutation operator is executed, in which TS is performed on individuals with higher fitness values. As for the other individuals with lower fitness values, mutation with a higher probability is carried out. Experiments using the proposed GATS feature selection method and three other methods, a standard GA, the multistart TS method, and ReliefF, were conducted on WorldView-2 and QuickBird images. The experimental results showed that the proposed method outperforms the other methods in terms of the final classification accuracy. PMID:29581721

  3. Identification of isomers and control of ionization and dissociation processes using dual-mass-spectrometer scheme and genetic algorithm optimization

    NASA Astrophysics Data System (ADS)

    Chen, Zhou; Tong, Qiu-Nan; Zhang, Cong-Cong; Hu, Zhan

    2015-04-01

    Identification of acetone and its two isomers, and the control of their ionization and dissociation processes are performed using a dual-mass-spectrometer scheme. The scheme employs two sets of time of flight mass spectrometers to simultaneously acquire the mass spectra of two different molecules under the irradiation of identically shaped femtosecond laser pulses. The optimal laser pulses are found using closed-loop learning method based on a genetic algorithm. Compared with the mass spectra of the two isomers that are obtained with the transform limited pulse, those obtained under the irradiation of the optimal laser pulse show large differences and the various reaction pathways of the two molecules are selectively controlled. The experimental results demonstrate that the scheme is quite effective and useful in studies of two molecules having common mass peaks, which makes a traditional single mass spectrometer unfeasible. Project supported by the National Basic Research Program of China (Grant No. 2013CB922200) and the National Natural Science Foundation of China (Grant No. 11374124).

  4. Blastocyst microinjection automation.

    PubMed

    Mattos, Leonardo S; Grant, Edward; Thresher, Randy; Kluckman, Kimberly

    2009-09-01

    Blastocyst microinjections are routinely involved in the process of creating genetically modified mice for biomedical research, but their efficiency is highly dependent on the skills of the operators. As a consequence, much time and resources are required for training microinjection personnel. This situation has been aggravated by the rapid growth of genetic research, which has increased the demand for mutant animals. Therefore, increased productivity and efficiency in this area are highly desired. Here, we pursue these goals through the automation of a previously developed teleoperated blastocyst microinjection system. This included the design of a new system setup to facilitate automation, the definition of rules for automatic microinjections, the implementation of video processing algorithms to extract feedback information from microscope images, and the creation of control algorithms for process automation. Experimentation conducted with this new system and operator assistance during the cells delivery phase demonstrated a 75% microinjection success rate. In addition, implantation of the successfully injected blastocysts resulted in a 53% birth rate and a 20% yield of chimeras. These results proved that the developed system was capable of automatic blastocyst penetration and retraction, demonstrating the success of major steps toward full process automation.

  5. A multiobjective hybrid genetic algorithm for the capacitated multipoint network design problem.

    PubMed

    Lo, C C; Chang, W H

    2000-01-01

    The capacitated multipoint network design problem (CMNDP) is NP-complete. In this paper, a hybrid genetic algorithm for CMNDP is proposed. The multiobjective hybrid genetic algorithm (MOHGA) differs from other genetic algorithms (GAs) mainly in its selection procedure. The concept of subpopulation is used in MOHGA. Four subpopulations are generated according to the elitism reservation strategy, the shifting Prufer vector, the stochastic universal sampling, and the complete random method, respectively. Mixing these four subpopulations produces the next generation population. The MOHGA can effectively search the feasible solution space due to population diversity. The MOHGA has been applied to CMNDP. By examining computational and analytical results, we notice that the MOHGA can find most nondominated solutions and is much more effective and efficient than other multiobjective GAs.

  6. A Hybrid Neural Network-Genetic Algorithm Technique for Aircraft Engine Performance Diagnostics

    NASA Technical Reports Server (NTRS)

    Kobayashi, Takahisa; Simon, Donald L.

    2001-01-01

    In this paper, a model-based diagnostic method, which utilizes Neural Networks and Genetic Algorithms, is investigated. Neural networks are applied to estimate the engine internal health, and Genetic Algorithms are applied for sensor bias detection and estimation. This hybrid approach takes advantage of the nonlinear estimation capability provided by neural networks while improving the robustness to measurement uncertainty through the application of Genetic Algorithms. The hybrid diagnostic technique also has the ability to rank multiple potential solutions for a given set of anomalous sensor measurements in order to reduce false alarms and missed detections. The performance of the hybrid diagnostic technique is evaluated through some case studies derived from a turbofan engine simulation. The results show this approach is promising for reliable diagnostics of aircraft engines.

  7. Genetic Algorithm Approaches for Actuator Placement

    NASA Technical Reports Server (NTRS)

    Crossley, William A.

    2000-01-01

    This research investigated genetic algorithm approaches for smart actuator placement to provide aircraft maneuverability without requiring hinged flaps or other control surfaces. The effort supported goals of the Multidisciplinary Design Optimization focus efforts in NASA's Aircraft au program. This work helped to properly identify various aspects of the genetic algorithm operators and parameters that allow for placement of discrete control actuators/effectors. An improved problem definition, including better definition of the objective function and constraints, resulted from this research effort. The work conducted for this research used a geometrically simple wing model; however, an increasing number of potential actuator placement locations were incorporated to illustrate the ability of the GA to determine promising actuator placement arrangements. This effort's major result is a useful genetic algorithm-based approach to assist in the discrete actuator/effector placement problem.

  8. Efficient path-based computations on pedigree graphs with compact encodings

    PubMed Central

    2012-01-01

    A pedigree is a diagram of family relationships, and it is often used to determine the mode of inheritance (dominant, recessive, etc.) of genetic diseases. Along with rapidly growing knowledge of genetics and accumulation of genealogy information, pedigree data is becoming increasingly important. In large pedigree graphs, path-based methods for efficiently computing genealogical measurements, such as inbreeding and kinship coefficients of individuals, depend on efficient identification and processing of paths. In this paper, we propose a new compact path encoding scheme on large pedigrees, accompanied by an efficient algorithm for identifying paths. We demonstrate the utilization of our proposed method by applying it to the inbreeding coefficient computation. We present time and space complexity analysis, and also manifest the efficiency of our method for evaluating inbreeding coefficients as compared to previous methods by experimental results using pedigree graphs with real and synthetic data. Both theoretical and experimental results demonstrate that our method is more scalable and efficient than previous methods in terms of time and space requirements. PMID:22536898

  9. A pipelined FPGA implementation of an encryption algorithm based on genetic algorithm

    NASA Astrophysics Data System (ADS)

    Thirer, Nonel

    2013-05-01

    With the evolution of digital data storage and exchange, it is essential to protect the confidential information from every unauthorized access. High performance encryption algorithms were developed and implemented by software and hardware. Also many methods to attack the cipher text were developed. In the last years, the genetic algorithm has gained much interest in cryptanalysis of cipher texts and also in encryption ciphers. This paper analyses the possibility to use the genetic algorithm as a multiple key sequence generator for an AES (Advanced Encryption Standard) cryptographic system, and also to use a three stages pipeline (with four main blocks: Input data, AES Core, Key generator, Output data) to provide a fast encryption and storage/transmission of a large amount of data.

  10. Modular analysis of the probabilistic genetic interaction network.

    PubMed

    Hou, Lin; Wang, Lin; Qian, Minping; Li, Dong; Tang, Chao; Zhu, Yunping; Deng, Minghua; Li, Fangting

    2011-03-15

    Epistatic Miniarray Profiles (EMAP) has enabled the mapping of large-scale genetic interaction networks; however, the quantitative information gained from EMAP cannot be fully exploited since the data are usually interpreted as a discrete network based on an arbitrary hard threshold. To address such limitations, we adopted a mixture modeling procedure to construct a probabilistic genetic interaction network and then implemented a Bayesian approach to identify densely interacting modules in the probabilistic network. Mixture modeling has been demonstrated as an effective soft-threshold technique of EMAP measures. The Bayesian approach was applied to an EMAP dataset studying the early secretory pathway in Saccharomyces cerevisiae. Twenty-seven modules were identified, and 14 of those were enriched by gold standard functional gene sets. We also conducted a detailed comparison with state-of-the-art algorithms, hierarchical cluster and Markov clustering. The experimental results show that the Bayesian approach outperforms others in efficiently recovering biologically significant modules.

  11. In silico Evolutionary Developmental Neurobiology and the Origin of Natural Language

    NASA Astrophysics Data System (ADS)

    Szathmáry, Eörs; Szathmáry, Zoltán; Ittzés, Péter; Orbaán, Geroő; Zachár, István; Huszár, Ferenc; Fedor, Anna; Varga, Máté; Számadó, Szabolcs

    It is justified to assume that part of our genetic endowment contributes to our language skills, yet it is impossible to tell at this moment exactly how genes affect the language faculty. We complement experimental biological studies by an in silico approach in that we simulate the evolution of neuronal networks under selection for language-related skills. At the heart of this project is the Evolutionary Neurogenetic Algorithm (ENGA) that is deliberately biomimetic. The design of the system was inspired by important biological phenomena such as brain ontogenesis, neuron morphologies, and indirect genetic encoding. Neuronal networks were selected and were allowed to reproduce as a function of their performance in the given task. The selected neuronal networks in all scenarios were able to solve the communication problem they had to face. The most striking feature of the model is that it works with highly indirect genetic encoding--just as brains do.

  12. Lithium cluster anions: photoelectron spectroscopy and ab initio calculations.

    PubMed

    Alexandrova, Anastassia N; Boldyrev, Alexander I; Li, Xiang; Sarkas, Harry W; Hendricks, Jay H; Arnold, Susan T; Bowen, Kit H

    2011-01-28

    Structural and energetic properties of small, deceptively simple anionic clusters of lithium, Li(n)(-), n = 3-7, were determined using a combination of anion photoelectron spectroscopy and ab initio calculations. The most stable isomers of each of these anions, the ones most likely to contribute to the photoelectron spectra, were found using the gradient embedded genetic algorithm program. Subsequently, state-of-the-art ab initio techniques, including time-dependent density functional theory, coupled cluster, and multireference configurational interactions methods, were employed to interpret the experimental spectra.

  13. Low-thrust orbit transfer optimization with refined Q-law and multi-objective genetic algorithm

    NASA Technical Reports Server (NTRS)

    Lee, Seungwon; Petropoulos, Anastassios E.; von Allmen, Paul

    2005-01-01

    An optimization method for low-thrust orbit transfers around a central body is developed using the Q-law and a multi-objective genetic algorithm. in the hybrid method, the Q-law generates candidate orbit transfers, and the multi-objective genetic algorithm optimizes the Q-law control parameters in order to simultaneously minimize both the consumed propellant mass and flight time of the orbit tranfer. This paper addresses the problem of finding optimal orbit transfers for low-thrust spacecraft.

  14. Genetic algorithm for neural networks optimization

    NASA Astrophysics Data System (ADS)

    Setyawati, Bina R.; Creese, Robert C.; Sahirman, Sidharta

    2004-11-01

    This paper examines the forecasting performance of multi-layer feed forward neural networks in modeling a particular foreign exchange rates, i.e. Japanese Yen/US Dollar. The effects of two learning methods, Back Propagation and Genetic Algorithm, in which the neural network topology and other parameters fixed, were investigated. The early results indicate that the application of this hybrid system seems to be well suited for the forecasting of foreign exchange rates. The Neural Networks and Genetic Algorithm were programmed using MATLAB«.

  15. Hybrid Architectures for Evolutionary Computing Algorithms

    DTIC Science & Technology

    2008-01-01

    other EC algorithms to FPGA Core Burns P1026/MAPLD 200532 Genetic Algorithm Hardware References S. Scott, A. Samal , and S. Seth, “HGA: A Hardware Based...on Parallel and Distributed Processing (IPPS/SPDP 󈨦), pp. 316-320, Proceedings. IEEE Computer Society 1998. [12] Scott, S. D. , Samal , A., and...Algorithm Hardware References S. Scott, A. Samal , and S. Seth, “HGA: A Hardware Based Genetic Algorithm”, Proceedings of the 1995 ACM Third

  16. MIP Models and Hybrid Algorithms for Simultaneous Job Splitting and Scheduling on Unrelated Parallel Machines

    PubMed Central

    Ozmutlu, H. Cenk

    2014-01-01

    We developed mixed integer programming (MIP) models and hybrid genetic-local search algorithms for the scheduling problem of unrelated parallel machines with job sequence and machine-dependent setup times and with job splitting property. The first contribution of this paper is to introduce novel algorithms which make splitting and scheduling simultaneously with variable number of subjobs. We proposed simple chromosome structure which is constituted by random key numbers in hybrid genetic-local search algorithm (GAspLA). Random key numbers are used frequently in genetic algorithms, but it creates additional difficulty when hybrid factors in local search are implemented. We developed algorithms that satisfy the adaptation of results of local search into the genetic algorithms with minimum relocation operation of genes' random key numbers. This is the second contribution of the paper. The third contribution of this paper is three developed new MIP models which are making splitting and scheduling simultaneously. The fourth contribution of this paper is implementation of the GAspLAMIP. This implementation let us verify the optimality of GAspLA for the studied combinations. The proposed methods are tested on a set of problems taken from the literature and the results validate the effectiveness of the proposed algorithms. PMID:24977204

  17. Series Hybrid Electric Vehicle Power System Optimization Based on Genetic Algorithm

    NASA Astrophysics Data System (ADS)

    Zhu, Tianjun; Li, Bin; Zong, Changfu; Wu, Yang

    2017-09-01

    Hybrid electric vehicles (HEV), compared with conventional vehicles, have complex structures and more component parameters. If variables optimization designs are carried on all these parameters, it will increase the difficulty and the convergence of algorithm program, so this paper chooses the parameters which has a major influence on the vehicle fuel consumption to make it all work at maximum efficiency. First, HEV powertrain components modelling are built. Second, taking a tandem hybrid structure as an example, genetic algorithm is used in this paper to optimize fuel consumption and emissions. Simulation results in ADVISOR verify the feasibility of the proposed genetic optimization algorithm.

  18. Multiple sequence alignment using multi-objective based bacterial foraging optimization algorithm.

    PubMed

    Rani, R Ranjani; Ramyachitra, D

    2016-12-01

    Multiple sequence alignment (MSA) is a widespread approach in computational biology and bioinformatics. MSA deals with how the sequences of nucleotides and amino acids are sequenced with possible alignment and minimum number of gaps between them, which directs to the functional, evolutionary and structural relationships among the sequences. Still the computation of MSA is a challenging task to provide an efficient accuracy and statistically significant results of alignments. In this work, the Bacterial Foraging Optimization Algorithm was employed to align the biological sequences which resulted in a non-dominated optimal solution. It employs Multi-objective, such as: Maximization of Similarity, Non-gap percentage, Conserved blocks and Minimization of gap penalty. BAliBASE 3.0 benchmark database was utilized to examine the proposed algorithm against other methods In this paper, two algorithms have been proposed: Hybrid Genetic Algorithm with Artificial Bee Colony (GA-ABC) and Bacterial Foraging Optimization Algorithm. It was found that Hybrid Genetic Algorithm with Artificial Bee Colony performed better than the existing optimization algorithms. But still the conserved blocks were not obtained using GA-ABC. Then BFO was used for the alignment and the conserved blocks were obtained. The proposed Multi-Objective Bacterial Foraging Optimization Algorithm (MO-BFO) was compared with widely used MSA methods Clustal Omega, Kalign, MUSCLE, MAFFT, Genetic Algorithm (GA), Ant Colony Optimization (ACO), Artificial Bee Colony (ABC), Particle Swarm Optimization (PSO) and Hybrid Genetic Algorithm with Artificial Bee Colony (GA-ABC). The final results show that the proposed MO-BFO algorithm yields better alignment than most widely used methods. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  19. Automatic page layout using genetic algorithms for electronic albuming

    NASA Astrophysics Data System (ADS)

    Geigel, Joe; Loui, Alexander C. P.

    2000-12-01

    In this paper, we describe a flexible system for automatic page layout that makes use of genetic algorithms for albuming applications. The system is divided into two modules, a page creator module which is responsible for distributing images amongst various album pages, and an image placement module which positions images on individual pages. Final page layouts are specified in a textual form using XML for printing or viewing over the Internet. The system makes use of genetic algorithms, a class of search and optimization algorithms that are based on the concepts of biological evolution, for generating solutions with fitness based on graphic design preferences supplied by the user. The genetic page layout algorithm has been incorporated into a web-based prototype system for interactive page layout over the Internet. The prototype system is built using client-server architecture and is implemented in java. The system described in this paper has demonstrated the feasibility of using genetic algorithms for automated page layout in albuming and web-based imaging applications. We believe that the system adequately proves the validity of the concept, providing creative layouts in a reasonable number of iterations. By optimizing the layout parameters of the fitness function, we hope to further improve the quality of the final layout in terms of user preference and computation speed.

  20. Frequency domain surface EMG sensor fusion for estimating finger forces.

    PubMed

    Potluri, Chandrasekhar; Kumar, Parmod; Anugolu, Madhavi; Urfer, Alex; Chiu, Steve; Naidu, D; Schoen, Marco P

    2010-01-01

    Extracting or estimating skeletal hand/finger forces using surface electro myographic (sEMG) signals poses many challenges due to cross-talk, noise, and a temporal and spatially modulated signal characteristics. Normal sEMG measurements are based on single sensor data. In this paper, array sensors are used along with a proposed sensor fusion scheme that result in a simple Multi-Input-Single-Output (MISO) transfer function. Experimental data is used along with system identification to find this MISO system. A Genetic Algorithm (GA) approach is employed to optimize the characteristics of the MISO system. The proposed fusion-based approach is tested experimentally and indicates improvement in finger/hand force estimation.

  1. Peak-to-average power ratio reduction in orthogonal frequency division multiplexing-based visible light communication systems using a modified partial transmit sequence technique

    NASA Astrophysics Data System (ADS)

    Liu, Yan; Deng, Honggui; Ren, Shuang; Tang, Chengying; Qian, Xuewen

    2018-01-01

    We propose an efficient partial transmit sequence technique based on genetic algorithm and peak-value optimization algorithm (GAPOA) to reduce high peak-to-average power ratio (PAPR) in visible light communication systems based on orthogonal frequency division multiplexing (VLC-OFDM). By analysis of hill-climbing algorithm's pros and cons, we propose the POA with excellent local search ability to further process the signals whose PAPR is still over the threshold after processed by genetic algorithm (GA). To verify the effectiveness of the proposed technique and algorithm, we evaluate the PAPR performance and the bit error rate (BER) performance and compare them with partial transmit sequence (PTS) technique based on GA (GA-PTS), PTS technique based on genetic and hill-climbing algorithm (GH-PTS), and PTS based on shuffled frog leaping algorithm and hill-climbing algorithm (SFLAHC-PTS). The results show that our technique and algorithm have not only better PAPR performance but also lower computational complexity and BER than GA-PTS, GH-PTS, and SFLAHC-PTS technique.

  2. Comparison of Genetic Algorithm, Particle Swarm Optimization and Biogeography-based Optimization for Feature Selection to Classify Clusters of Microcalcifications

    NASA Astrophysics Data System (ADS)

    Khehra, Baljit Singh; Pharwaha, Amar Partap Singh

    2017-04-01

    Ductal carcinoma in situ (DCIS) is one type of breast cancer. Clusters of microcalcifications (MCCs) are symptoms of DCIS that are recognized by mammography. Selection of robust features vector is the process of selecting an optimal subset of features from a large number of available features in a given problem domain after the feature extraction and before any classification scheme. Feature selection reduces the feature space that improves the performance of classifier and decreases the computational burden imposed by using many features on classifier. Selection of an optimal subset of features from a large number of available features in a given problem domain is a difficult search problem. For n features, the total numbers of possible subsets of features are 2n. Thus, selection of an optimal subset of features problem belongs to the category of NP-hard problems. In this paper, an attempt is made to find the optimal subset of MCCs features from all possible subsets of features using genetic algorithm (GA), particle swarm optimization (PSO) and biogeography-based optimization (BBO). For simulation, a total of 380 benign and malignant MCCs samples have been selected from mammogram images of DDSM database. A total of 50 features extracted from benign and malignant MCCs samples are used in this study. In these algorithms, fitness function is correct classification rate of classifier. Support vector machine is used as a classifier. From experimental results, it is also observed that the performance of PSO-based and BBO-based algorithms to select an optimal subset of features for classifying MCCs as benign or malignant is better as compared to GA-based algorithm.

  3. The McGill Interactive Pediatric OncoGenetic Guidelines: An approach to identifying pediatric oncology patients most likely to benefit from a genetic evaluation.

    PubMed

    Goudie, Catherine; Coltin, Hallie; Witkowski, Leora; Mourad, Stephanie; Malkin, David; Foulkes, William D

    2017-08-01

    Identifying cancer predisposition syndromes in children with tumors is crucial, yet few clinical guidelines exist to identify children at high risk of having germline mutations. The McGill Interactive Pediatric OncoGenetic Guidelines project aims to create a validated pediatric guideline in the form of a smartphone/tablet application using algorithms to process clinical data and help determine whether to refer a child for genetic assessment. This paper discusses the initial stages of the project, focusing on its overall structure, the methodology underpinning the algorithms, and the upcoming algorithm validation process. © 2017 Wiley Periodicals, Inc.

  4. Optimization of genomic selection training populations with a genetic algorithm

    USDA-ARS?s Scientific Manuscript database

    In this article, we derive a computationally efficient statistic to measure the reliability of estimates of genetic breeding values for a fixed set of genotypes based on a given training set of genotypes and phenotypes. We adopt a genetic algorithm scheme to find a training set of certain size from ...

  5. Fireworks algorithm for mean-VaR/CVaR models

    NASA Astrophysics Data System (ADS)

    Zhang, Tingting; Liu, Zhifeng

    2017-10-01

    Intelligent algorithms have been widely applied to portfolio optimization problems. In this paper, we introduce a novel intelligent algorithm, named fireworks algorithm, to solve the mean-VaR/CVaR model for the first time. The results show that, compared with the classical genetic algorithm, fireworks algorithm not only improves the optimization accuracy and the optimization speed, but also makes the optimal solution more stable. We repeat our experiments at different confidence levels and different degrees of risk aversion, and the results are robust. It suggests that fireworks algorithm has more advantages than genetic algorithm in solving the portfolio optimization problem, and it is feasible and promising to apply it into this field.

  6. Boolean network inference from time series data incorporating prior biological knowledge.

    PubMed

    Haider, Saad; Pal, Ranadip

    2012-01-01

    Numerous approaches exist for modeling of genetic regulatory networks (GRNs) but the low sampling rates often employed in biological studies prevents the inference of detailed models from experimental data. In this paper, we analyze the issues involved in estimating a model of a GRN from single cell line time series data with limited time points. We present an inference approach for a Boolean Network (BN) model of a GRN from limited transcriptomic or proteomic time series data based on prior biological knowledge of connectivity, constraints on attractor structure and robust design. We applied our inference approach to 6 time point transcriptomic data on Human Mammary Epithelial Cell line (HMEC) after application of Epidermal Growth Factor (EGF) and generated a BN with a plausible biological structure satisfying the data. We further defined and applied a similarity measure to compare synthetic BNs and BNs generated through the proposed approach constructed from transitions of various paths of the synthetic BNs. We have also compared the performance of our algorithm with two existing BN inference algorithms. Through theoretical analysis and simulations, we showed the rarity of arriving at a BN from limited time series data with plausible biological structure using random connectivity and absence of structure in data. The framework when applied to experimental data and data generated from synthetic BNs were able to estimate BNs with high similarity scores. Comparison with existing BN inference algorithms showed the better performance of our proposed algorithm for limited time series data. The proposed framework can also be applied to optimize the connectivity of a GRN from experimental data when the prior biological knowledge on regulators is limited or not unique.

  7. Surface normal coupling to multiple-slot and cover-slotted silicon nanocrystalline waveguides and ring resonators

    NASA Astrophysics Data System (ADS)

    Covey, John; Chen, Ray T.

    2014-03-01

    Grating couplers are ideal for coupling into the tightly confined propagation modes of semiconductor waveguides. In addition, nonlinear optics has benefited from the sub-diffraction limit confinement of horizontal slot waveguides. By combining these two advancements, slot-based nonlinear optics with mode areas less than 0.02 μm2 can become as routine as twisting fiber connectors together. Surface normal fiber alignment to a chip is also highly desirable from time, cost, and manufacturing considerations. To meet these considerable design challenges, a custom genetic algorithm is created which, starting from purely random designs, creates a unique four stage grating coupler for two novel horizontal slot waveguide platforms. For horizontal multiple-slot waveguides filled with silicon nanocrystal, a theoretical fiber-towaveguide coupling efficiency of 68% is obtained. For thin silicon waveguides clad with optically active silicon nanocrystal, known as cover-slot waveguides, a theoretical fiber-to-waveguide coupling efficiency of 47% is obtained, and 1 dB and 3 dB theoretical bandwidths of 70 nm and 150 nm are obtained, respectively. Both waveguide platforms are fabricated from scratch, and their respective on-chip grating couplers are experimentally measured from a standard single mode fiber array that is mounted surface normally. The horizontal multiple-slot grating coupler achieved an experimental 60% coupling efficiency, and the horizontal cover-slot grating coupler achieved an experimental 38.7% coupling efficiency, with an extrapolated 1 dB bandwidth of 66 nm. This report demonstrates the promise of genetic algorithm-based design by reducing to practice the first large bandwidth vertical grating coupler to a novel silicon nanocrystal horizontal cover-slot waveguide.

  8. Dynamic traffic assignment : genetic algorithms approach

    DOT National Transportation Integrated Search

    1997-01-01

    Real-time route guidance is a promising approach to alleviating congestion on the nations highways. A dynamic traffic assignment model is central to the development of guidance strategies. The artificial intelligence technique of genetic algorithm...

  9. Genetic algorithm based input selection for a neural network function approximator with applications to SSME health monitoring

    NASA Technical Reports Server (NTRS)

    Peck, Charles C.; Dhawan, Atam P.; Meyer, Claudia M.

    1991-01-01

    A genetic algorithm is used to select the inputs to a neural network function approximator. In the application considered, modeling critical parameters of the space shuttle main engine (SSME), the functional relationship between measured parameters is unknown and complex. Furthermore, the number of possible input parameters is quite large. Many approaches have been used for input selection, but they are either subjective or do not consider the complex multivariate relationships between parameters. Due to the optimization and space searching capabilities of genetic algorithms they were employed to systematize the input selection process. The results suggest that the genetic algorithm can generate parameter lists of high quality without the explicit use of problem domain knowledge. Suggestions for improving the performance of the input selection process are also provided.

  10. Accelerating global optimization of aerodynamic shapes using a new surrogate-assisted parallel genetic algorithm

    NASA Astrophysics Data System (ADS)

    Ebrahimi, Mehdi; Jahangirian, Alireza

    2017-12-01

    An efficient strategy is presented for global shape optimization of wing sections with a parallel genetic algorithm. Several computational techniques are applied to increase the convergence rate and the efficiency of the method. A variable fidelity computational evaluation method is applied in which the expensive Navier-Stokes flow solver is complemented by an inexpensive multi-layer perceptron neural network for the objective function evaluations. A population dispersion method that consists of two phases, of exploration and refinement, is developed to improve the convergence rate and the robustness of the genetic algorithm. Owing to the nature of the optimization problem, a parallel framework based on the master/slave approach is used. The outcomes indicate that the method is able to find the global optimum with significantly lower computational time in comparison to the conventional genetic algorithm.

  11. [Reconstruction of Vehicle-human Crash Accident and Injury Analysis Based on 3D Laser Scanning, Multi-rigid-body Reconstruction and Optimized Genetic Algorithm].

    PubMed

    Sun, J; Wang, T; Li, Z D; Shao, Y; Zhang, Z Y; Feng, H; Zou, D H; Chen, Y J

    2017-12-01

    To reconstruct a vehicle-bicycle-cyclist crash accident and analyse the injuries using 3D laser scanning technology, multi-rigid-body dynamics and optimized genetic algorithm, and to provide biomechanical basis for the forensic identification of death cause. The vehicle was measured by 3D laser scanning technology. The multi-rigid-body models of cyclist, bicycle and vehicle were developed based on the measurements. The value range of optimal variables was set. A multi-objective genetic algorithm and the nondominated sorting genetic algorithm were used to find the optimal solutions, which were compared to the record of the surveillance video around the accident scene. The reconstruction result of laser scanning on vehicle was satisfactory. In the optimal solutions found by optimization method of genetic algorithm, the dynamical behaviours of dummy, bicycle and vehicle corresponded to that recorded by the surveillance video. The injury parameters of dummy were consistent with the situation and position of the real injuries on the cyclist in accident. The motion status before accident, damage process by crash and mechanical analysis on the injury of the victim can be reconstructed using 3D laser scanning technology, multi-rigid-body dynamics and optimized genetic algorithm, which have application value in the identification of injury manner and analysis of death cause in traffic accidents. Copyright© by the Editorial Department of Journal of Forensic Medicine

  12. Performance comparison of genetic algorithms and particle swarm optimization for model integer programming bus timetabling problem

    NASA Astrophysics Data System (ADS)

    Wihartiko, F. D.; Wijayanti, H.; Virgantari, F.

    2018-03-01

    Genetic Algorithm (GA) is a common algorithm used to solve optimization problems with artificial intelligence approach. Similarly, the Particle Swarm Optimization (PSO) algorithm. Both algorithms have different advantages and disadvantages when applied to the case of optimization of the Model Integer Programming for Bus Timetabling Problem (MIPBTP), where in the case of MIPBTP will be found the optimal number of trips confronted with various constraints. The comparison results show that the PSO algorithm is superior in terms of complexity, accuracy, iteration and program simplicity in finding the optimal solution.

  13. Research on laser marking speed optimization by using genetic algorithm.

    PubMed

    Wang, Dongyun; Yu, Qiwei; Zhang, Yu

    2015-01-01

    Laser Marking Machine is the most common coding equipment on product packaging lines. However, the speed of laser marking has become a bottleneck of production. In order to remove this bottleneck, a new method based on a genetic algorithm is designed. On the basis of this algorithm, a controller was designed and simulations and experiments were performed. The results show that using this algorithm could effectively improve laser marking efficiency by 25%.

  14. P-Finder: Reconstruction of Signaling Networks from Protein-Protein Interactions and GO Annotations.

    PubMed

    Young-Rae Cho; Yanan Xin; Speegle, Greg

    2015-01-01

    Because most complex genetic diseases are caused by defects of cell signaling, illuminating a signaling cascade is essential for understanding their mechanisms. We present three novel computational algorithms to reconstruct signaling networks between a starting protein and an ending protein using genome-wide protein-protein interaction (PPI) networks and gene ontology (GO) annotation data. A signaling network is represented as a directed acyclic graph in a merged form of multiple linear pathways. An advanced semantic similarity metric is applied for weighting PPIs as the preprocessing of all three methods. The first algorithm repeatedly extends the list of nodes based on path frequency towards an ending protein. The second algorithm repeatedly appends edges based on the occurrence of network motifs which indicate the link patterns more frequently appearing in a PPI network than in a random graph. The last algorithm uses the information propagation technique which iteratively updates edge orientations based on the path strength and merges the selected directed edges. Our experimental results demonstrate that the proposed algorithms achieve higher accuracy than previous methods when they are tested on well-studied pathways of S. cerevisiae. Furthermore, we introduce an interactive web application tool, called P-Finder, to visualize reconstructed signaling networks.

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tumuluru, Jaya Shankar; McCulloch, Richard Chet James

    In this work a new hybrid genetic algorithm was developed which combines a rudimentary adaptive steepest ascent hill climbing algorithm with a sophisticated evolutionary algorithm in order to optimize complex multivariate design problems. By combining a highly stochastic algorithm (evolutionary) with a simple deterministic optimization algorithm (adaptive steepest ascent) computational resources are conserved and the solution converges rapidly when compared to either algorithm alone. In genetic algorithms natural selection is mimicked by random events such as breeding and mutation. In the adaptive steepest ascent algorithm each variable is perturbed by a small amount and the variable that caused the mostmore » improvement is incremented by a small step. If the direction of most benefit is exactly opposite of the previous direction with the most benefit then the step size is reduced by a factor of 2, thus the step size adapts to the terrain. A graphical user interface was created in MATLAB to provide an interface between the hybrid genetic algorithm and the user. Additional features such as bounding the solution space and weighting the objective functions individually are also built into the interface. The algorithm developed was tested to optimize the functions developed for a wood pelleting process. Using process variables (such as feedstock moisture content, die speed, and preheating temperature) pellet properties were appropriately optimized. Specifically, variables were found which maximized unit density, bulk density, tapped density, and durability while minimizing pellet moisture content and specific energy consumption. The time and computational resources required for the optimization were dramatically decreased using the hybrid genetic algorithm when compared to MATLAB's native evolutionary optimization tool.« less

  16. Automated Test Assembly for Cognitive Diagnosis Models Using a Genetic Algorithm

    ERIC Educational Resources Information Center

    Finkelman, Matthew; Kim, Wonsuk; Roussos, Louis A.

    2009-01-01

    Much recent psychometric literature has focused on cognitive diagnosis models (CDMs), a promising class of instruments used to measure the strengths and weaknesses of examinees. This article introduces a genetic algorithm to perform automated test assembly alongside CDMs. The algorithm is flexible in that it can be applied whether the goal is to…

  17. Design Genetic Algorithm Optimization Education Software Based Fuzzy Controller for a Tricopter Fly Path Planning

    ERIC Educational Resources Information Center

    Tran, Huu-Khoa; Chiou, Juing -Shian; Peng, Shou-Tao

    2016-01-01

    In this paper, the feasibility of a Genetic Algorithm Optimization (GAO) education software based Fuzzy Logic Controller (GAO-FLC) for simulating the flight motion control of Unmanned Aerial Vehicles (UAVs) is designed. The generated flight trajectories integrate the optimized Scaling Factors (SF) fuzzy controller gains by using GAO algorithm. The…

  18. Electricity Usage Scheduling in Smart Building Environments Using Smart Devices

    PubMed Central

    Lee, Eunji; Bahn, Hyokyung

    2013-01-01

    With the recent advances in smart grid technologies as well as the increasing dissemination of smart meters, the electricity usage of every moment can be detected in modern smart building environments. Thus, the utility company adopts different price of electricity at each time slot considering the peak time. This paper presents a new electricity usage scheduling algorithm for smart buildings that adopts real-time pricing of electricity. The proposed algorithm detects the change of electricity prices by making use of a smart device and changes the power mode of each electric device dynamically. Specifically, we formulate the electricity usage scheduling problem as a real-time task scheduling problem and show that it is a complex search problem that has an exponential time complexity. An efficient heuristic based on genetic algorithms is performed on a smart device to cut down the huge searching space and find a reasonable schedule within a feasible time budget. Experimental results with various building conditions show that the proposed algorithm reduces the electricity charge of a smart building by 25.6% on average and up to 33.4%. PMID:24453860

  19. Electricity usage scheduling in smart building environments using smart devices.

    PubMed

    Lee, Eunji; Bahn, Hyokyung

    2013-01-01

    With the recent advances in smart grid technologies as well as the increasing dissemination of smart meters, the electricity usage of every moment can be detected in modern smart building environments. Thus, the utility company adopts different price of electricity at each time slot considering the peak time. This paper presents a new electricity usage scheduling algorithm for smart buildings that adopts real-time pricing of electricity. The proposed algorithm detects the change of electricity prices by making use of a smart device and changes the power mode of each electric device dynamically. Specifically, we formulate the electricity usage scheduling problem as a real-time task scheduling problem and show that it is a complex search problem that has an exponential time complexity. An efficient heuristic based on genetic algorithms is performed on a smart device to cut down the huge searching space and find a reasonable schedule within a feasible time budget. Experimental results with various building conditions show that the proposed algorithm reduces the electricity charge of a smart building by 25.6% on average and up to 33.4%.

  20. A new adaptive algorithm for automated feature extraction in exponentially damped signals for health monitoring of smart structures

    NASA Astrophysics Data System (ADS)

    Qarib, Hossein; Adeli, Hojjat

    2015-12-01

    In this paper authors introduce a new adaptive signal processing technique for feature extraction and parameter estimation in noisy exponentially damped signals. The iterative 3-stage method is based on the adroit integration of the strengths of parametric and nonparametric methods such as multiple signal categorization, matrix pencil, and empirical mode decomposition algorithms. The first stage is a new adaptive filtration or noise removal scheme. The second stage is a hybrid parametric-nonparametric signal parameter estimation technique based on an output-only system identification technique. The third stage is optimization of estimated parameters using a combination of the primal-dual path-following interior point algorithm and genetic algorithm. The methodology is evaluated using a synthetic signal and a signal obtained experimentally from transverse vibrations of a steel cantilever beam. The method is successful in estimating the frequencies accurately. Further, it estimates the damping exponents. The proposed adaptive filtration method does not include any frequency domain manipulation. Consequently, the time domain signal is not affected as a result of frequency domain and inverse transformations.

  1. Assessment of Gamma-Ray Spectra Analysis Method Utilizing the Fireworks Algorithm for various Error Measures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Alamaniotis, Miltiadis; Tsoukalas, Lefteri H.

    2018-01-01

    Significant role in enhancing nuclear nonproliferation plays the analysis of obtained data and the inference of the presence or not of special nuclear materials in them. Among various types of measurements, gamma-ray spectra is the widest used type of data utilized for analysis in nonproliferation. In this chapter, a method that employs the fireworks algorithm (FWA) for analyzing gamma-ray spectra aiming at detecting gamma signatures is presented. In particular FWA is utilized to fit a set of known signatures to a measured spectrum by optimizing an objective function, with non-zero coefficients expressing the detected signatures. FWA is tested on amore » set of experimentally obtained measurements and various objective functions -MSE, RMSE, Theil-2, MAE, MAPE, MAP- with results exhibiting its potential in providing high accuracy and high precision of detected signatures. Furthermore, FWA is benchmarked against genetic algorithms, and multiple linear regression with results exhibiting its superiority over the rest tested algorithms with respect to precision for MAE, MAPE and MAP measures.« less

  2. Quaternionic representation of the genetic code.

    PubMed

    Carlevaro, C Manuel; Irastorza, Ramiro M; Vericat, Fernando

    2016-03-01

    A heuristic diagram of the evolution of the standard genetic code is presented. It incorporates, in a way that resembles the energy levels of an atom, the physical notion of broken symmetry and it is consistent with original ideas by Crick on the origin and evolution of the code as well as with the chronological order of appearance of the amino acids along the evolution as inferred from work that mixtures known experimental results with theoretical speculations. Suggested by the diagram we propose a Hamilton quaternions based mathematical representation of the code as it stands now-a-days. The central object in the description is a codon function that assigns to each amino acid an integer quaternion in such a way that the observed code degeneration is preserved. We emphasize the advantages of a quaternionic representation of amino acids taking as an example the folding of proteins. With this aim we propose an algorithm to go from the quaternions sequence to the protein three dimensional structure which can be compared with the corresponding experimental one stored at the Protein Data Bank. In our criterion the mathematical representation of the genetic code in terms of quaternions merits to be taken into account because it describes not only most of the known properties of the genetic code but also opens new perspectives that are mainly derived from the close relationship between quaternions and rotations. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  3. A Parallel Genetic Algorithm to Discover Patterns in Genetic Markers that Indicate Predisposition to Multifactorial Disease

    PubMed Central

    Rausch, Tobias; Thomas, Alun; Camp, Nicola J.; Cannon-Albright, Lisa A.; Facelli, Julio C.

    2008-01-01

    This paper describes a novel algorithm to analyze genetic linkage data using pattern recognition techniques and genetic algorithms (GA). The method allows a search for regions of the chromosome that may contain genetic variations that jointly predispose individuals for a particular disease. The method uses correlation analysis, filtering theory and genetic algorithms (GA) to achieve this goal. Because current genome scans use from hundreds to hundreds of thousands of markers, two versions of the method have been implemented. The first is an exhaustive analysis version that can be used to visualize, explore, and analyze small genetic data sets for two marker correlations; the second is a GA version, which uses a parallel implementation allowing searches of higher-order correlations in large data sets. Results on simulated data sets indicate that the method can be informative in the identification of major disease loci and gene-gene interactions in genome-wide linkage data and that further exploration of these techniques is justified. The results presented for both variants of the method show that it can help genetic epidemiologists to identify promising combinations of genetic factors that might predispose to complex disorders. In particular, the correlation analysis of IBD expression patterns might hint to possible gene-gene interactions and the filtering might be a fruitful approach to distinguish true correlation signals from noise. PMID:18547558

  4. Secure Scientific Applications Scheduling Technique for Cloud Computing Environment Using Global League Championship Algorithm

    PubMed Central

    Abdulhamid, Shafi’i Muhammad; Abd Latiff, Muhammad Shafie; Abdul-Salaam, Gaddafi; Hussain Madni, Syed Hamid

    2016-01-01

    Cloud computing system is a huge cluster of interconnected servers residing in a datacenter and dynamically provisioned to clients on-demand via a front-end interface. Scientific applications scheduling in the cloud computing environment is identified as NP-hard problem due to the dynamic nature of heterogeneous resources. Recently, a number of metaheuristics optimization schemes have been applied to address the challenges of applications scheduling in the cloud system, without much emphasis on the issue of secure global scheduling. In this paper, scientific applications scheduling techniques using the Global League Championship Algorithm (GBLCA) optimization technique is first presented for global task scheduling in the cloud environment. The experiment is carried out using CloudSim simulator. The experimental results show that, the proposed GBLCA technique produced remarkable performance improvement rate on the makespan that ranges between 14.44% to 46.41%. It also shows significant reduction in the time taken to securely schedule applications as parametrically measured in terms of the response time. In view of the experimental results, the proposed technique provides better-quality scheduling solution that is suitable for scientific applications task execution in the Cloud Computing environment than the MinMin, MaxMin, Genetic Algorithm (GA) and Ant Colony Optimization (ACO) scheduling techniques. PMID:27384239

  5. Secure Scientific Applications Scheduling Technique for Cloud Computing Environment Using Global League Championship Algorithm.

    PubMed

    Abdulhamid, Shafi'i Muhammad; Abd Latiff, Muhammad Shafie; Abdul-Salaam, Gaddafi; Hussain Madni, Syed Hamid

    2016-01-01

    Cloud computing system is a huge cluster of interconnected servers residing in a datacenter and dynamically provisioned to clients on-demand via a front-end interface. Scientific applications scheduling in the cloud computing environment is identified as NP-hard problem due to the dynamic nature of heterogeneous resources. Recently, a number of metaheuristics optimization schemes have been applied to address the challenges of applications scheduling in the cloud system, without much emphasis on the issue of secure global scheduling. In this paper, scientific applications scheduling techniques using the Global League Championship Algorithm (GBLCA) optimization technique is first presented for global task scheduling in the cloud environment. The experiment is carried out using CloudSim simulator. The experimental results show that, the proposed GBLCA technique produced remarkable performance improvement rate on the makespan that ranges between 14.44% to 46.41%. It also shows significant reduction in the time taken to securely schedule applications as parametrically measured in terms of the response time. In view of the experimental results, the proposed technique provides better-quality scheduling solution that is suitable for scientific applications task execution in the Cloud Computing environment than the MinMin, MaxMin, Genetic Algorithm (GA) and Ant Colony Optimization (ACO) scheduling techniques.

  6. Genetic algorithm for nuclear data evaluation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Arthur, Jennifer Ann

    These are slides on genetic algorithm for nuclear data evaluation. The following is covered: initial population, fitness (outer loop), calculate fitness, selection (first part of inner loop), reproduction (second part of inner loop), solution, and examples.

  7. Parallel approach for bioinspired algorithms

    NASA Astrophysics Data System (ADS)

    Zaporozhets, Dmitry; Zaruba, Daria; Kulieva, Nina

    2018-05-01

    In the paper, a probabilistic parallel approach based on the population heuristic, such as a genetic algorithm, is suggested. The authors proposed using a multithreading approach at the micro level at which new alternative solutions are generated. On each iteration, several threads that independently used the same population to generate new solutions can be started. After the work of all threads, a selection operator combines obtained results in the new population. To confirm the effectiveness of the suggested approach, the authors have developed software on the basis of which experimental computations can be carried out. The authors have considered a classic optimization problem – finding a Hamiltonian cycle in a graph. Experiments show that due to the parallel approach at the micro level, increment of running speed can be obtained on graphs with 250 and more vertices.

  8. Optimal design of the first stage of the plate-fin heat exchanger for the EAST cryogenic system

    NASA Astrophysics Data System (ADS)

    Qingfeng, JIANG; Zhigang, ZHU; Qiyong, ZHANG; Ming, ZHUANG; Xiaofei, LU

    2018-03-01

    The size of the heat exchanger is an important factor determining the dimensions of the cold box in helium cryogenic systems. In this paper, a counter-flow multi-stream plate-fin heat exchanger is optimized by means of a spatial interpolation method coupled with a hybrid genetic algorithm. Compared with empirical correlations, this spatial interpolation algorithm based on a kriging model can be adopted to more precisely predict the Colburn heat transfer factors and Fanning friction factors of offset-strip fins. Moreover, strict computational fluid dynamics simulations can be carried out to predict the heat transfer and friction performance in the absence of reliable experimental data. Within the constraints of heat exchange requirements, maximum allowable pressure drop, existing manufacturing techniques and structural strength, a mathematical model of an optimized design with discrete and continuous variables based on a hybrid genetic algorithm is established in order to minimize the volume. The results show that for the first-stage heat exchanger in the EAST refrigerator, the structural size could be decreased from the original 2.200 × 0.600 × 0.627 (m3) to the optimized 1.854 × 0.420 × 0.340 (m3), with a large reduction in volume. The current work demonstrates that the proposed method could be a useful tool to achieve optimization in an actual engineering project during the practical design process.

  9. Chaotic Particle Swarm Optimization with Mutation for Classification

    PubMed Central

    Assarzadeh, Zahra; Naghsh-Nilchi, Ahmad Reza

    2015-01-01

    In this paper, a chaotic particle swarm optimization with mutation-based classifier particle swarm optimization is proposed to classify patterns of different classes in the feature space. The introduced mutation operators and chaotic sequences allows us to overcome the problem of early convergence into a local minima associated with particle swarm optimization algorithms. That is, the mutation operator sharpens the convergence and it tunes the best possible solution. Furthermore, to remove the irrelevant data and reduce the dimensionality of medical datasets, a feature selection approach using binary version of the proposed particle swarm optimization is introduced. In order to demonstrate the effectiveness of our proposed classifier, mutation-based classifier particle swarm optimization, it is checked out with three sets of data classifications namely, Wisconsin diagnostic breast cancer, Wisconsin breast cancer and heart-statlog, with different feature vector dimensions. The proposed algorithm is compared with different classifier algorithms including k-nearest neighbor, as a conventional classifier, particle swarm-classifier, genetic algorithm, and Imperialist competitive algorithm-classifier, as more sophisticated ones. The performance of each classifier was evaluated by calculating the accuracy, sensitivity, specificity and Matthews's correlation coefficient. The experimental results show that the mutation-based classifier particle swarm optimization unequivocally performs better than all the compared algorithms. PMID:25709937

  10. Hybrid Model Based on Genetic Algorithms and SVM Applied to Variable Selection within Fruit Juice Classification

    PubMed Central

    Fernandez-Lozano, C.; Canto, C.; Gestal, M.; Andrade-Garda, J. M.; Rabuñal, J. R.; Dorado, J.; Pazos, A.

    2013-01-01

    Given the background of the use of Neural Networks in problems of apple juice classification, this paper aim at implementing a newly developed method in the field of machine learning: the Support Vector Machines (SVM). Therefore, a hybrid model that combines genetic algorithms and support vector machines is suggested in such a way that, when using SVM as a fitness function of the Genetic Algorithm (GA), the most representative variables for a specific classification problem can be selected. PMID:24453933

  11. Fuel management optimization using genetic algorithms and expert knowledge

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    DeChaine, M.D.; Feltus, M.A.

    1996-09-01

    The CIGARO fuel management optimization code based on genetic algorithms is described and tested. The test problem optimized the core lifetime for a pressurized water reactor with a penalty function constraint on the peak normalized power. A bit-string genotype encoded the loading patterns, and genotype bias was reduced with additional bits. Expert knowledge about fuel management was incorporated into the genetic algorithm. Regional crossover exchanged physically adjacent fuel assemblies and improved the optimization slightly. Biasing the initial population toward a known priority table significantly improved the optimization.

  12. Optimal placement of tuning masses on truss structures by genetic algorithms

    NASA Technical Reports Server (NTRS)

    Ponslet, Eric; Haftka, Raphael T.; Cudney, Harley H.

    1993-01-01

    Optimal placement of tuning masses, actuators and other peripherals on large space structures is a combinatorial optimization problem. This paper surveys several techniques for solving this problem. The genetic algorithm approach to the solution of the placement problem is described in detail. An example of minimizing the difference between the two lowest frequencies of a laboratory truss by adding tuning masses is used for demonstrating some of the advantages of genetic algorithms. The relative efficiencies of different codings are compared using the results of a large number of optimization runs.

  13. Application of a Genetic Algorithm and Multi Agent System to Explore Emergent Patterns of Social Rationality and a Distress-Based Model for Deceit in the Workplace

    DTIC Science & Technology

    2008-06-01

    postponed the fulfillment of her own Masters Degree by at least 18 months so that I would have the opportunity to earn mine. She is smart , lovely...GENETIC ALGORITHM AND MULTI AGENT SYSTEM TO EXPLORE EMERGENT PATTERNS OF SOCIAL RATIONALITY AND A DISTRESS-BASED MODEL FOR DECEIT IN THE WORKPLACE...of a Genetic Algorithm and Mutli Agent System to Explore Emergent Patterns of Social Rationality and a Distress-Based Model for Deceit in the

  14. Multi-objective Optimization Design of Gear Reducer Based on Adaptive Genetic Algorithms

    NASA Astrophysics Data System (ADS)

    Li, Rui; Chang, Tian; Wang, Jianwei; Wei, Xiaopeng; Wang, Jinming

    2008-11-01

    An adaptive Genetic Algorithm (GA) is introduced to solve the multi-objective optimized design of the reducer. Firstly, according to the structure, strength, etc. in a reducer, a multi-objective optimized model of the helical gear reducer is established. And then an adaptive GA based on a fuzzy controller is introduced, aiming at the characteristics of multi-objective, multi-parameter, multi-constraint conditions. Finally, a numerical example is illustrated to show the advantages of this approach and the effectiveness of an adaptive genetic algorithm used in optimized design of a reducer.

  15. Multi-scale genetic dynamic modelling II: application to synthetic biology: an algorithmic Markov chain based approach.

    PubMed

    Kirkilionis, Markus; Janus, Ulrich; Sbano, Luca

    2011-09-01

    We model in detail a simple synthetic genetic clock that was engineered in Atkinson et al. (Cell 113(5):597-607, 2003) using Escherichia coli as a host organism. Based on this engineered clock its theoretical description uses the modelling framework presented in Kirkilionis et al. (Theory Biosci. doi: 10.1007/s12064-011-0125-0 , 2011, this volume). The main goal of this accompanying article was to illustrate that parts of the modelling process can be algorithmically automatised once the model framework we called 'average dynamics' is accepted (Sbano and Kirkilionis, WMI Preprint 7/2007, 2008c; Kirkilionis and Sbano, Adv Complex Syst 13(3):293-326, 2010). The advantage of the 'average dynamics' framework is that system components (especially in genetics) can be easier represented in the model. In particular, if once discovered and characterised, specific molecular players together with their function can be incorporated. This means that, for example, the 'gene' concept becomes more clear, for example, in the way the genetic component would react under different regulatory conditions. Using the framework it has become a realistic aim to link mathematical modelling to novel tools of bioinformatics in the future, at least if the number of regulatory units can be estimated. This should hold in any case in synthetic environments due to the fact that the different synthetic genetic components are simply known (Elowitz and Leibler, Nature 403(6767):335-338, 2000; Gardner et al., Nature 403(6767):339-342, 2000; Hasty et al., Nature 420(6912):224-230, 2002). The paper illustrates therefore as a necessary first step how a detailed modelling of molecular interactions with known molecular components leads to a dynamic mathematical model that can be compared to experimental results on various levels or scales. The different genetic modules or components are represented in different detail by model variants. We explain how the framework can be used for investigating other more complex genetic systems in terms of regulation and feedback.

  16. Investigation on application of genetic algorithms to optimal reactive power dispatch of power systems

    NASA Astrophysics Data System (ADS)

    Wu, Q. H.; Ma, J. T.

    1993-09-01

    A primary investigation into application of genetic algorithms in optimal reactive power dispatch and voltage control is presented. The application was achieved, based on (the United Kingdom) National Grid 48 bus network model, using a novel genetic search approach. Simulation results, compared with that obtained using nonlinear programming methods, are included to show the potential of applications of the genetic search methodology in power system economical and secure operations.

  17. Algorithme intelligent d'optimisation d'un design structurel de grande envergure

    NASA Astrophysics Data System (ADS)

    Dominique, Stephane

    The implementation of an automated decision support system in the field of design and structural optimisation can give a significant advantage to any industry working on mechanical designs. Indeed, by providing solution ideas to a designer or by upgrading existing design solutions while the designer is not at work, the system may reduce the project cycle time, or allow more time to produce a better design. This thesis presents a new approach to automate a design process based on Case-Based Reasoning (CBR), in combination with a new genetic algorithm named Genetic Algorithm with Territorial core Evolution (GATE). This approach was developed in order to reduce the operating cost of the process. However, as the system implementation cost is quite expensive, the approach is better suited for large scale design problem, and particularly for design problems that the designer plans to solve for many different specification sets. First, the CBR process uses a databank filled with every known solution to similar design problems. Then, the closest solutions to the current problem in term of specifications are selected. After this, during the adaptation phase, an artificial neural network (ANN) interpolates amongst known solutions to produce an additional solution to the current problem using the current specifications as inputs. Each solution produced and selected by the CBR is then used to initialize the population of an island of the genetic algorithm. The algorithm will optimise the solution further during the refinement phase. Using progressive refinement, the algorithm starts using only the most important variables for the problem. Then, as the optimisation progress, the remaining variables are gradually introduced, layer by layer. The genetic algorithm that is used is a new algorithm specifically created during this thesis to solve optimisation problems from the field of mechanical device structural design. The algorithm is named GATE, and is essentially a real number genetic algorithm that prevents new individuals to be born too close to previously evaluated solutions. The restricted area becomes smaller or larger during the optimisation to allow global or local search when necessary. Also, a new search operator named Substitution Operator is incorporated in GATE. This operator allows an ANN surrogate model to guide the algorithm toward the most promising areas of the design space. The suggested CBR approach and GATE were tested on several simple test problems, as well as on the industrial problem of designing a gas turbine engine rotor's disc. These results are compared to other results obtained for the same problems by many other popular optimisation algorithms, such as (depending of the problem) gradient algorithms, binary genetic algorithm, real number genetic algorithm, genetic algorithm using multiple parents crossovers, differential evolution genetic algorithm, Hookes & Jeeves generalized pattern search method and POINTER from the software I-SIGHT 3.5. Results show that GATE is quite competitive, giving the best results for 5 of the 6 constrained optimisation problem. GATE also provided the best results of all on problem produced by a Maximum Set Gaussian landscape generator. Finally, GATE provided a disc 4.3% lighter than the best other tested algorithm (POINTER) for the gas turbine engine rotor's disc problem. One drawback of GATE is a lesser efficiency for highly multimodal unconstrained problems, for which he gave quite poor results with respect to its implementation cost. To conclude, according to the preliminary results obtained during this thesis, the suggested CBR process, combined with GATE, seems to be a very good candidate to automate and accelerate the structural design of mechanical devices, potentially reducing significantly the cost of industrial preliminary design processes.

  18. Routing design and fleet allocation optimization of freeway service patrol: Improved results using genetic algorithm

    NASA Astrophysics Data System (ADS)

    Sun, Xiuqiao; Wang, Jian

    2018-07-01

    Freeway service patrol (FSP), is considered to be an effective method for incident management and can help transportation agency decision-makers alter existing route coverage and fleet allocation. This paper investigates the FSP problem of patrol routing design and fleet allocation, with the objective of minimizing the overall average incident response time. While the simulated annealing (SA) algorithm and its improvements have been applied to solve this problem, they often become trapped in local optimal solution. Moreover, the issue of searching efficiency remains to be further addressed. In this paper, we employ the genetic algorithm (GA) and SA to solve the FSP problem. To maintain population diversity and avoid premature convergence, niche strategy is incorporated into the traditional genetic algorithm. We also employ elitist strategy to speed up the convergence. Numerical experiments have been conducted with the help of the Sioux Falls network. Results show that the GA slightly outperforms the dual-based greedy (DBG) algorithm, the very large-scale neighborhood searching (VLNS) algorithm, the SA algorithm and the scenario algorithm.

  19. Research on Laser Marking Speed Optimization by Using Genetic Algorithm

    PubMed Central

    Wang, Dongyun; Yu, Qiwei; Zhang, Yu

    2015-01-01

    Laser Marking Machine is the most common coding equipment on product packaging lines. However, the speed of laser marking has become a bottleneck of production. In order to remove this bottleneck, a new method based on a genetic algorithm is designed. On the basis of this algorithm, a controller was designed and simulations and experiments were performed. The results show that using this algorithm could effectively improve laser marking efficiency by 25%. PMID:25955831

  20. Parana Basin Structure from Multi-Objective Inversion of Surface Wave and Receiver Function by Competent Genetic Algorithm

    NASA Astrophysics Data System (ADS)

    An, M.; Assumpcao, M.

    2003-12-01

    The joint inversion of receiver function and surface wave is an effective way to diminish the influences of the strong tradeoff among parameters and the different sensitivity to the model parameters in their respective inversions, but the inversion problem becomes more complex. Multi-objective problems can be much more complicated than single-objective inversion in the model selection and optimization. If objectives are involved and conflicting, models can be ordered only partially. In this case, Pareto-optimal preference should be used to select solutions. On the other hand, the inversion to get only a few optimal solutions can not deal properly with the strong tradeoff between parameters, the uncertainties in the observation, the geophysical complexities and even the incompetency of the inversion technique. The effective way is to retrieve the geophysical information statistically from many acceptable solutions, which requires more competent global algorithms. Competent genetic algorithms recently proposed are far superior to the conventional genetic algorithm and can solve hard problems quickly, reliably and accurately. In this work we used one of competent genetic algorithms, Bayesian Optimization Algorithm as the main inverse procedure. This algorithm uses Bayesian networks to draw out inherited information and can use Pareto-optimal preference in the inversion. With this algorithm, the lithospheric structure of Paran"› basin is inverted to fit both the observations of inter-station surface wave dispersion and receiver function.

  1. Genetic Algorithms to Optimizatize Lecturer Assessment's Criteria

    NASA Astrophysics Data System (ADS)

    Jollyta, Deny; Johan; Hajjah, Alyauma

    2017-12-01

    The lecturer assessment criteria is used as a measurement of the lecturer's performance in a college environment. To determine the value for a criteriais complicated and often leads to doubt. The absence of a standard valuefor each assessment criteria will affect the final results of the assessment and become less presentational data for the leader of college in taking various policies relate to reward and punishment. The Genetic Algorithm comes as an algorithm capable of solving non-linear problems. Using chromosomes in the random initial population, one of the presentations is binary, evaluates the fitness function and uses crossover genetic operator and mutation to obtain the desired crossbreed. It aims to obtain the most optimum criteria values in terms of the fitness function of each chromosome. The training results show that Genetic Algorithm able to produce the optimal values of lecturer assessment criteria so that can be usedby the college as a standard value for lecturer assessment criteria.

  2. A theoretical comparison of evolutionary algorithms and simulated annealing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, W.E.

    1995-08-28

    This paper theoretically compares the performance of simulated annealing and evolutionary algorithms. Our main result is that under mild conditions a wide variety of evolutionary algorithms can be shown to have greater performance than simulated annealing after a sufficiently large number of function evaluations. This class of EAs includes variants of evolutionary strategie and evolutionary programming, the canonical genetic algorithm, as well as a variety of genetic algorithms that have been applied to combinatorial optimization problems. The proof of this result is based on a performance analysis of a very general class of stochastic optimization algorithms, which has implications formore » the performance of a variety of other optimization algorithm.« less

  3. A global optimization algorithm inspired in the behavior of selfish herds.

    PubMed

    Fausto, Fernando; Cuevas, Erik; Valdivia, Arturo; González, Adrián

    2017-10-01

    In this paper, a novel swarm optimization algorithm called the Selfish Herd Optimizer (SHO) is proposed for solving global optimization problems. SHO is based on the simulation of the widely observed selfish herd behavior manifested by individuals within a herd of animals subjected to some form of predation risk. In SHO, individuals emulate the predatory interactions between groups of prey and predators by two types of search agents: the members of a selfish herd (the prey) and a pack of hungry predators. Depending on their classification as either a prey or a predator, each individual is conducted by a set of unique evolutionary operators inspired by such prey-predator relationship. These unique traits allow SHO to improve the balance between exploration and exploitation without altering the population size. To illustrate the proficiency and robustness of the proposed method, it is compared to other well-known evolutionary optimization approaches such as Particle Swarm Optimization (PSO), Artificial Bee Colony (ABC), Firefly Algorithm (FA), Differential Evolution (DE), Genetic Algorithms (GA), Crow Search Algorithm (CSA), Dragonfly Algorithm (DA), Moth-flame Optimization Algorithm (MOA) and Sine Cosine Algorithm (SCA). The comparison examines several standard benchmark functions, commonly considered within the literature of evolutionary algorithms. The experimental results show the remarkable performance of our proposed approach against those of the other compared methods, and as such SHO is proven to be an excellent alternative to solve global optimization problems. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Optimization of chiral lattice based metastructures for broadband vibration suppression using genetic algorithms

    NASA Astrophysics Data System (ADS)

    Abdeljaber, Osama; Avci, Onur; Inman, Daniel J.

    2016-05-01

    One of the major challenges in civil, mechanical, and aerospace engineering is to develop vibration suppression systems with high efficiency and low cost. Recent studies have shown that high damping performance at broadband frequencies can be achieved by incorporating periodic inserts with tunable dynamic properties as internal resonators in structural systems. Structures featuring these kinds of inserts are referred to as metamaterials inspired structures or metastructures. Chiral lattice inserts exhibit unique characteristics such as frequency bandgaps which can be tuned by varying the parameters that define the lattice topology. Recent analytical and experimental investigations have shown that broadband vibration attenuation can be achieved by including chiral lattices as internal resonators in beam-like structures. However, these studies have suggested that the performance of chiral lattice inserts can be maximized by utilizing an efficient optimization technique to obtain the optimal topology of the inserted lattice. In this study, an automated optimization procedure based on a genetic algorithm is applied to obtain the optimal set of parameters that will result in chiral lattice inserts tuned properly to reduce the global vibration levels of a finite-sized beam. Genetic algorithms are considered in this study due to their capability of dealing with complex and insufficiently understood optimization problems. In the optimization process, the basic parameters that govern the geometry of periodic chiral lattices including the number of circular nodes, the thickness of the ligaments, and the characteristic angle are considered. Additionally, a new set of parameters is introduced to enable the optimization process to explore non-periodic chiral designs. Numerical simulations are carried out to demonstrate the efficiency of the optimization process.

  5. Three-way parallel independent component analysis for imaging genetics using multi-objective optimization.

    PubMed

    Ulloa, Alvaro; Jingyu Liu; Vergara, Victor; Jiayu Chen; Calhoun, Vince; Pattichis, Marios

    2014-01-01

    In the biomedical field, current technology allows for the collection of multiple data modalities from the same subject. In consequence, there is an increasing interest for methods to analyze multi-modal data sets. Methods based on independent component analysis have proven to be effective in jointly analyzing multiple modalities, including brain imaging and genetic data. This paper describes a new algorithm, three-way parallel independent component analysis (3pICA), for jointly identifying genomic loci associated with brain function and structure. The proposed algorithm relies on the use of multi-objective optimization methods to identify correlations among the modalities and maximally independent sources within modality. We test the robustness of the proposed approach by varying the effect size, cross-modality correlation, noise level, and dimensionality of the data. Simulation results suggest that 3p-ICA is robust to data with SNR levels from 0 to 10 dB and effect-sizes from 0 to 3, while presenting its best performance with high cross-modality correlations, and more than one subject per 1,000 variables. In an experimental study with 112 human subjects, the method identified links between a genetic component (pointing to brain function and mental disorder associated genes, including PPP3CC, KCNQ5, and CYP7B1), a functional component related to signal decreases in the default mode network during the task, and a brain structure component indicating increases of gray matter in brain regions of the default mode region. Although such findings need further replication, the simulation and in-vivo results validate the three-way parallel ICA algorithm presented here as a useful tool in biomedical data decomposition applications.

  6. Design of Genetic Algorithms for Topology Control of Unmanned Vehicles

    DTIC Science & Technology

    2010-01-01

    decentralised topology control mechanism distributed among active running software agents to achieve a uniform spread of terrestrial unmanned vehicles...14. ABSTRACT We present genetic algorithms (GAs) as a decentralised topology control mechanism distributed among active running software agents to...inspired topology control algorithm. The topology control of UVs using a decentralised solution over an unknown geographical terrain is a challenging

  7. Multi-heuristic dynamic task allocation using genetic algorithms in a heterogeneous distributed system

    PubMed Central

    Page, Andrew J.; Keane, Thomas M.; Naughton, Thomas J.

    2010-01-01

    We present a multi-heuristic evolutionary task allocation algorithm to dynamically map tasks to processors in a heterogeneous distributed system. It utilizes a genetic algorithm, combined with eight common heuristics, in an effort to minimize the total execution time. It operates on batches of unmapped tasks and can preemptively remap tasks to processors. The algorithm has been implemented on a Java distributed system and evaluated with a set of six problems from the areas of bioinformatics, biomedical engineering, computer science and cryptography. Experiments using up to 150 heterogeneous processors show that the algorithm achieves better efficiency than other state-of-the-art heuristic algorithms. PMID:20862190

  8. Using an improved association rules mining optimization algorithm in web-based mobile-learning system

    NASA Astrophysics Data System (ADS)

    Huang, Yin; Chen, Jianhua; Xiong, Shaojun

    2009-07-01

    Mobile-Learning (M-learning) makes many learners get the advantages of both traditional learning and E-learning. Currently, Web-based Mobile-Learning Systems have created many new ways and defined new relationships between educators and learners. Association rule mining is one of the most important fields in data mining and knowledge discovery in databases. Rules explosion is a serious problem which causes great concerns, as conventional mining algorithms often produce too many rules for decision makers to digest. Since Web-based Mobile-Learning System collects vast amounts of student profile data, data mining and knowledge discovery techniques can be applied to find interesting relationships between attributes of learners, assessments, the solution strategies adopted by learners and so on. Therefore ,this paper focus on a new data-mining algorithm, combined with the advantages of genetic algorithm and simulated annealing algorithm , called ARGSA(Association rules based on an improved Genetic Simulated Annealing Algorithm), to mine the association rules. This paper first takes advantage of the Parallel Genetic Algorithm and Simulated Algorithm designed specifically for discovering association rules. Moreover, the analysis and experiment are also made to show the proposed method is superior to the Apriori algorithm in this Mobile-Learning system.

  9. Light-extraction enhancement for light-emitting diodes: a firefly-inspired structure refined by the genetic algorithm

    NASA Astrophysics Data System (ADS)

    Bay, Annick; Mayer, Alexandre

    2014-09-01

    The efficiency of light-emitting diodes (LED) has increased significantly over the past few years, but the overall efficiency is still limited by total internal reflections due to the high dielectric-constant contrast between the incident and emergent media. The bioluminescent organ of fireflies gave incentive for light-extraction enhance-ment studies. A specific factory-roof shaped structure was shown, by means of light-propagation simulations and measurements, to enhance light extraction significantly. In order to achieve a similar effect for light-emitting diodes, the structure needs to be adapted to the specific set-up of LEDs. In this context simulations were carried out to determine the best geometrical parameters. In the present work, the search for a geometry that maximizes the extraction of light has been conducted by using a genetic algorithm. The idealized structure considered previously was generalized to a broader variety of shapes. The genetic algorithm makes it possible to search simultaneously over a wider range of parameters. It is also significantly less time-consuming than the previous approach that was based on a systematic scan on parameters. The results of the genetic algorithm show that (1) the calculations can be performed in a smaller amount of time and (2) the light extraction can be enhanced even more significantly by using optimal parameters determined by the genetic algorithm for the generalized structure. The combination of the genetic algorithm with the Rigorous Coupled Waves Analysis method constitutes a strong simulation tool, which provides us with adapted designs for enhancing light extraction from light-emitting diodes.

  10. Empirical valence bond models for reactive potential energy surfaces: a parallel multilevel genetic program approach.

    PubMed

    Bellucci, Michael A; Coker, David F

    2011-07-28

    We describe a new method for constructing empirical valence bond potential energy surfaces using a parallel multilevel genetic program (PMLGP). Genetic programs can be used to perform an efficient search through function space and parameter space to find the best functions and sets of parameters that fit energies obtained by ab initio electronic structure calculations. Building on the traditional genetic program approach, the PMLGP utilizes a hierarchy of genetic programming on two different levels. The lower level genetic programs are used to optimize coevolving populations in parallel while the higher level genetic program (HLGP) is used to optimize the genetic operator probabilities of the lower level genetic programs. The HLGP allows the algorithm to dynamically learn the mutation or combination of mutations that most effectively increase the fitness of the populations, causing a significant increase in the algorithm's accuracy and efficiency. The algorithm's accuracy and efficiency is tested against a standard parallel genetic program with a variety of one-dimensional test cases. Subsequently, the PMLGP is utilized to obtain an accurate empirical valence bond model for proton transfer in 3-hydroxy-gamma-pyrone in gas phase and protic solvent. © 2011 American Institute of Physics

  11. Focusing of light through turbid media by curve fitting optimization

    NASA Astrophysics Data System (ADS)

    Gong, Changmei; Wu, Tengfei; Liu, Jietao; Li, Huijuan; Shao, Xiaopeng; Zhang, Jianqi

    2016-12-01

    The construction of wavefront phase plays a critical role in focusing light through turbid media. We introduce the curve fitting algorithm (CFA) into the feedback control procedure for wavefront optimization. Unlike the existing continuous sequential algorithm (CSA), the CFA locates the optimal phase by fitting a curve to the measured signals. Simulation results show that, similar to the genetic algorithm (GA), the proposed CFA technique is far less susceptible to the experimental noise than the CSA. Furthermore, only three measurements of feedback signals are enough for CFA to fit the optimal phase while obtaining a higher focal intensity than the CSA and the GA, dramatically shortening the optimization time by a factor of 3 compared with the CSA and the GA. The proposed CFA approach can be applied to enhance the focus intensity and boost the focusing speed in the fields of biological imaging, particle trapping, laser therapy, and so on, and might help to focus light through dynamic turbid media.

  12. Artificial immune algorithm for multi-depot vehicle scheduling problems

    NASA Astrophysics Data System (ADS)

    Wu, Zhongyi; Wang, Donggen; Xia, Linyuan; Chen, Xiaoling

    2008-10-01

    In the fast-developing logistics and supply chain management fields, one of the key problems in the decision support system is that how to arrange, for a lot of customers and suppliers, the supplier-to-customer assignment and produce a detailed supply schedule under a set of constraints. Solutions to the multi-depot vehicle scheduling problems (MDVRP) help in solving this problem in case of transportation applications. The objective of the MDVSP is to minimize the total distance covered by all vehicles, which can be considered as delivery costs or time consumption. The MDVSP is one of nondeterministic polynomial-time hard (NP-hard) problem which cannot be solved to optimality within polynomial bounded computational time. Many different approaches have been developed to tackle MDVSP, such as exact algorithm (EA), one-stage approach (OSA), two-phase heuristic method (TPHM), tabu search algorithm (TSA), genetic algorithm (GA) and hierarchical multiplex structure (HIMS). Most of the methods mentioned above are time consuming and have high risk to result in local optimum. In this paper, a new search algorithm is proposed to solve MDVSP based on Artificial Immune Systems (AIS), which are inspirited by vertebrate immune systems. The proposed AIS algorithm is tested with 30 customers and 6 vehicles located in 3 depots. Experimental results show that the artificial immune system algorithm is an effective and efficient method for solving MDVSP problems.

  13. MULTIOBJECTIVE PARALLEL GENETIC ALGORITHM FOR WASTE MINIMIZATION

    EPA Science Inventory

    In this research we have developed an efficient multiobjective parallel genetic algorithm (MOPGA) for waste minimization problems. This MOPGA integrates PGAPack (Levine, 1996) and NSGA-II (Deb, 2000) with novel modifications. PGAPack is a master-slave parallel implementation of a...

  14. Inverse simulation system for manual-controlled rendezvous and docking based on artificial neural network

    NASA Astrophysics Data System (ADS)

    Zhou, Wanmeng; Wang, Hua; Tang, Guojin; Guo, Shuai

    2016-09-01

    The time-consuming experimental method for handling qualities assessment cannot meet the increasing fast design requirements for the manned space flight. As a tool for the aircraft handling qualities research, the model-predictive-control structured inverse simulation (MPC-IS) has potential applications in the aerospace field to guide the astronauts' operations and evaluate the handling qualities more effectively. Therefore, this paper establishes MPC-IS for the manual-controlled rendezvous and docking (RVD) and proposes a novel artificial neural network inverse simulation system (ANN-IS) to further decrease the computational cost. The novel system was obtained by replacing the inverse model of MPC-IS with the artificial neural network. The optimal neural network was trained by the genetic Levenberg-Marquardt algorithm, and finally determined by the Levenberg-Marquardt algorithm. In order to validate MPC-IS and ANN-IS, the manual-controlled RVD experiments on the simulator were carried out. The comparisons between simulation results and experimental data demonstrated the validity of two systems and the high computational efficiency of ANN-IS.

  15. Evolutionary algorithm for vehicle driving cycle generation.

    PubMed

    Perhinschi, Mario G; Marlowe, Christopher; Tamayo, Sergio; Tu, Jun; Wayne, W Scott

    2011-09-01

    Modeling transit bus emissions and fuel economy requires a large amount of experimental data over wide ranges of operational conditions. Chassis dynamometer tests are typically performed using representative driving cycles defined based on vehicle instantaneous speed as sequences of "microtrips", which are intervals between consecutive vehicle stops. Overall significant parameters of the driving cycle, such as average speed, stops per mile, kinetic intensity, and others, are used as independent variables in the modeling process. Performing tests at all the necessary combinations of parameters is expensive and time consuming. In this paper, a methodology is proposed for building driving cycles at prescribed independent variable values using experimental data through the concatenation of "microtrips" isolated from a limited number of standard chassis dynamometer test cycles. The selection of the adequate "microtrips" is achieved through a customized evolutionary algorithm. The genetic representation uses microtrip definitions as genes. Specific mutation, crossover, and karyotype alteration operators have been defined. The Roulette-Wheel selection technique with elitist strategy drives the optimization process, which consists of minimizing the errors to desired overall cycle parameters. This utility is part of the Integrated Bus Information System developed at West Virginia University.

  16. Strain gage selection in loads equations using a genetic algorithm

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Traditionally, structural loads are measured using strain gages. A loads calibration test must be done before loads can be accurately measured. In one measurement method, a series of point loads is applied to the structure, and loads equations are derived via the least squares curve fitting algorithm using the strain gage responses to the applied point loads. However, many research structures are highly instrumented with strain gages, and the number and selection of gages used in a loads equation can be problematic. This paper presents an improved technique using a genetic algorithm to choose the strain gages used in the loads equations. Also presented are a comparison of the genetic algorithm performance with the current T-value technique and a variant known as the Best Step-down technique. Examples are shown using aerospace vehicle wings of high and low aspect ratio. In addition, a significant limitation in the current methods is revealed. The genetic algorithm arrived at a comparable or superior set of gages with significantly less human effort, and could be applied in instances when the current methods could not.

  17. A hybrid genetic algorithm for solving bi-objective traveling salesman problems

    NASA Astrophysics Data System (ADS)

    Ma, Mei; Li, Hecheng

    2017-08-01

    The traveling salesman problem (TSP) is a typical combinatorial optimization problem, in a traditional TSP only tour distance is taken as a unique objective to be minimized. When more than one optimization objective arises, the problem is known as a multi-objective TSP. In the present paper, a bi-objective traveling salesman problem (BOTSP) is taken into account, where both the distance and the cost are taken as optimization objectives. In order to efficiently solve the problem, a hybrid genetic algorithm is proposed. Firstly, two satisfaction degree indices are provided for each edge by considering the influences of the distance and the cost weight. The first satisfaction degree is used to select edges in a “rough” way, while the second satisfaction degree is executed for a more “refined” choice. Secondly, two satisfaction degrees are also applied to generate new individuals in the iteration process. Finally, based on genetic algorithm framework as well as 2-opt selection strategy, a hybrid genetic algorithm is proposed. The simulation illustrates the efficiency of the proposed algorithm.

  18. Using a genetic algorithm as an optimal band selector in the mid and thermal infrared (2.5-14 μm) to discriminate vegetation species.

    PubMed

    Ullah, Saleem; Groen, Thomas A; Schlerf, Martin; Skidmore, Andrew K; Nieuwenhuis, Willem; Vaiphasa, Chaichoke

    2012-01-01

    Genetic variation between various plant species determines differences in their physio-chemical makeup and ultimately in their hyperspectral emissivity signatures. The hyperspectral emissivity signatures, on the one hand, account for the subtle physio-chemical changes in the vegetation, but on the other hand, highlight the problem of high dimensionality. The aim of this paper is to investigate the performance of genetic algorithms coupled with the spectral angle mapper (SAM) to identify a meaningful subset of wavebands sensitive enough to discriminate thirteen broadleaved vegetation species from the laboratory measured hyperspectral emissivities. The performance was evaluated using an overall classification accuracy and Jeffries Matusita distance. For the multiple plant species, the targeted bands based on genetic algorithms resulted in a high overall classification accuracy (90%). Concentrating on the pairwise comparison results, the selected wavebands based on genetic algorithms resulted in higher Jeffries Matusita (J-M) distances than randomly selected wavebands did. This study concludes that targeted wavebands from leaf emissivity spectra are able to discriminate vegetation species.

  19. Improved genetic algorithm for the protein folding problem by use of a Cartesian combination operator.

    PubMed Central

    Rabow, A. A.; Scheraga, H. A.

    1996-01-01

    We have devised a Cartesian combination operator and coding scheme for improving the performance of genetic algorithms applied to the protein folding problem. The genetic coding consists of the C alpha Cartesian coordinates of the protein chain. The recombination of the genes of the parents is accomplished by: (1) a rigid superposition of one parent chain on the other, to make the relation of Cartesian coordinates meaningful, then, (2) the chains of the children are formed through a linear combination of the coordinates of their parents. The children produced with this Cartesian combination operator scheme have similar topology and retain the long-range contacts of their parents. The new scheme is significantly more efficient than the standard genetic algorithm methods for locating low-energy conformations of proteins. The considerable superiority of genetic algorithms over Monte Carlo optimization methods is also demonstrated. We have also devised a new dynamic programming lattice fitting procedure for use with the Cartesian combination operator method. The procedure finds excellent fits of real-space chains to the lattice while satisfying bond-length, bond-angle, and overlap constraints. PMID:8880904

  20. The genetic algorithm: A robust method for stress inversion

    NASA Astrophysics Data System (ADS)

    Thakur, Prithvi; Srivastava, Deepak C.; Gupta, Pravin K.

    2017-01-01

    The stress inversion of geological or geophysical observations is a nonlinear problem. In most existing methods, it is solved by linearization, under certain assumptions. These linear algorithms not only oversimplify the problem but also are vulnerable to entrapment of the solution in a local optimum. We propose the use of a nonlinear heuristic technique, the genetic algorithm, which searches the global optimum without making any linearizing assumption or simplification. The algorithm mimics the natural evolutionary processes of selection, crossover and mutation and, minimizes a composite misfit function for searching the global optimum, the fittest stress tensor. The validity and efficacy of the algorithm are demonstrated by a series of tests on synthetic and natural fault-slip observations in different tectonic settings and also in situations where the observations are noisy. It is shown that the genetic algorithm is superior to other commonly practised methods, in particular, in those tectonic settings where none of the principal stresses is directed vertically and/or the given data set is noisy.

  1. USING GENETIC ALGORITHMS TO DESIGN ENVIRONMENTALLY FRIENDLY PROCESSES

    EPA Science Inventory

    Genetic algorithm calculations are applied to the design of chemical processes to achieve improvements in environmental and economic performance. By finding the set of Pareto (i.e., non-dominated) solutions one can see how different objectives, such as environmental and economic ...

  2. The application of immune genetic algorithm in main steam temperature of PID control of BP network

    NASA Astrophysics Data System (ADS)

    Li, Han; Zhen-yu, Zhang

    In order to overcome the uncertainties, large delay, large inertia and nonlinear property of the main steam temperature controlled object in the power plant, a neural network intelligent PID control system based on immune genetic algorithm and BP neural network is designed. Using the immune genetic algorithm global search optimization ability and good convergence, optimize the weights of the neural network, meanwhile adjusting PID parameters using BP network. The simulation result shows that the system is superior to conventional PID control system in the control of quality and robustness.

  3. Real coded genetic algorithm for fuzzy time series prediction

    NASA Astrophysics Data System (ADS)

    Jain, Shilpa; Bisht, Dinesh C. S.; Singh, Phool; Mathpal, Prakash C.

    2017-10-01

    Genetic Algorithm (GA) forms a subset of evolutionary computing, rapidly growing area of Artificial Intelligence (A.I.). Some variants of GA are binary GA, real GA, messy GA, micro GA, saw tooth GA, differential evolution GA. This research article presents a real coded GA for predicting enrollments of University of Alabama. Data of Alabama University is a fuzzy time series. Here, fuzzy logic is used to predict enrollments of Alabama University and genetic algorithm optimizes fuzzy intervals. Results are compared to other eminent author works and found satisfactory, and states that real coded GA are fast and accurate.

  4. Air data system optimization using a genetic algorithm

    NASA Technical Reports Server (NTRS)

    Deshpande, Samir M.; Kumar, Renjith R.; Seywald, Hans; Siemers, Paul M., III

    1992-01-01

    An optimization method for flush-orifice air data system design has been developed using the Genetic Algorithm approach. The optimization of the orifice array minimizes the effect of normally distributed random noise in the pressure readings on the calculation of air data parameters, namely, angle of attack, sideslip angle and freestream dynamic pressure. The optimization method is applied to the design of Pressure Distribution/Air Data System experiment (PD/ADS) proposed for inclusion in the Aeroassist Flight Experiment (AFE). Results obtained by the Genetic Algorithm method are compared to the results obtained by conventional gradient search method.

  5. Simultaneous optimization of the cavity heat load and trip rates in linacs using a genetic algorithm

    DOE PAGES

    Terzić, Balša; Hofler, Alicia S.; Reeves, Cody J.; ...

    2014-10-15

    In this paper, a genetic algorithm-based optimization is used to simultaneously minimize two competing objectives guiding the operation of the Jefferson Lab's Continuous Electron Beam Accelerator Facility linacs: cavity heat load and radio frequency cavity trip rates. The results represent a significant improvement to the standard linac energy management tool and thereby could lead to a more efficient Continuous Electron Beam Accelerator Facility configuration. This study also serves as a proof of principle of how a genetic algorithm can be used for optimizing other linac-based machines.

  6. A novel hybrid genetic algorithm for optimal design of IPM machines for electric vehicle

    NASA Astrophysics Data System (ADS)

    Wang, Aimeng; Guo, Jiayu

    2017-12-01

    A novel hybrid genetic algorithm (HGA) is proposed to optimize the rotor structure of an IPM machine which is used in EV application. The finite element (FE) simulation results of the HGA design is compared with the genetic algorithm (GA) design and those before optimized. It is shown that the performance of the IPMSM is effectively improved by employing the GA and HGA, especially by HGA. Moreover, higher flux-weakening capability and less magnet usage are also obtained. Therefore, the validity of HGA method in IPMSM optimization design is verified.

  7. Abdomen disease diagnosis in CT images using flexiscale curvelet transform and improved genetic algorithm.

    PubMed

    Sethi, Gaurav; Saini, B S

    2015-12-01

    This paper presents an abdomen disease diagnostic system based on the flexi-scale curvelet transform, which uses different optimal scales for extracting features from computed tomography (CT) images. To optimize the scale of the flexi-scale curvelet transform, we propose an improved genetic algorithm. The conventional genetic algorithm assumes that fit parents will likely produce the healthiest offspring that leads to the least fit parents accumulating at the bottom of the population, reducing the fitness of subsequent populations and delaying the optimal solution search. In our improved genetic algorithm, combining the chromosomes of a low-fitness and a high-fitness individual increases the probability of producing high-fitness offspring. Thereby, all of the least fit parent chromosomes are combined with high fit parent to produce offspring for the next population. In this way, the leftover weak chromosomes cannot damage the fitness of subsequent populations. To further facilitate the search for the optimal solution, our improved genetic algorithm adopts modified elitism. The proposed method was applied to 120 CT abdominal images; 30 images each of normal subjects, cysts, tumors and stones. The features extracted by the flexi-scale curvelet transform were more discriminative than conventional methods, demonstrating the potential of our method as a diagnostic tool for abdomen diseases.

  8. Genetic Bee Colony (GBC) algorithm: A new gene selection method for microarray cancer classification.

    PubMed

    Alshamlan, Hala M; Badr, Ghada H; Alohali, Yousef A

    2015-06-01

    Naturally inspired evolutionary algorithms prove effectiveness when used for solving feature selection and classification problems. Artificial Bee Colony (ABC) is a relatively new swarm intelligence method. In this paper, we propose a new hybrid gene selection method, namely Genetic Bee Colony (GBC) algorithm. The proposed algorithm combines the used of a Genetic Algorithm (GA) along with Artificial Bee Colony (ABC) algorithm. The goal is to integrate the advantages of both algorithms. The proposed algorithm is applied to a microarray gene expression profile in order to select the most predictive and informative genes for cancer classification. In order to test the accuracy performance of the proposed algorithm, extensive experiments were conducted. Three binary microarray datasets are use, which include: colon, leukemia, and lung. In addition, another three multi-class microarray datasets are used, which are: SRBCT, lymphoma, and leukemia. Results of the GBC algorithm are compared with our recently proposed technique: mRMR when combined with the Artificial Bee Colony algorithm (mRMR-ABC). We also compared the combination of mRMR with GA (mRMR-GA) and Particle Swarm Optimization (mRMR-PSO) algorithms. In addition, we compared the GBC algorithm with other related algorithms that have been recently published in the literature, using all benchmark datasets. The GBC algorithm shows superior performance as it achieved the highest classification accuracy along with the lowest average number of selected genes. This proves that the GBC algorithm is a promising approach for solving the gene selection problem in both binary and multi-class cancer classification. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. Image processing meta-algorithm development via genetic manipulation of existing algorithm graphs

    NASA Astrophysics Data System (ADS)

    Schalkoff, Robert J.; Shaaban, Khaled M.

    1999-07-01

    Automatic algorithm generation for image processing applications is not a new idea, however previous work is either restricted to morphological operates or impractical. In this paper, we show recent research result in the development and use of meta-algorithms, i.e. algorithms which lead to new algorithms. Although the concept is generally applicable, the application domain in this work is restricted to image processing. The meta-algorithm concept described in this paper is based upon out work in dynamic algorithm. The paper first present the concept of dynamic algorithms which, on the basis of training and archived algorithmic experience embedded in an algorithm graph (AG), dynamically adjust the sequence of operations applied to the input image data. Each node in the tree-based representation of a dynamic algorithm with out degree greater than 2 is a decision node. At these nodes, the algorithm examines the input data and determines which path will most likely achieve the desired results. This is currently done using nearest-neighbor classification. The details of this implementation are shown. The constrained perturbation of existing algorithm graphs, coupled with a suitable search strategy, is one mechanism to achieve meta-algorithm an doffers rich potential for the discovery of new algorithms. In our work, a meta-algorithm autonomously generates new dynamic algorithm graphs via genetic recombination of existing algorithm graphs. The AG representation is well suited to this genetic-like perturbation, using a commonly- employed technique in artificial neural network synthesis, namely the blueprint representation of graphs. A number of exam. One of the principal limitations of our current approach is the need for significant human input in the learning phase. Efforts to overcome this limitation are discussed. Future research directions are indicated.

  10. Applications of information theory, genetic algorithms, and neural models to predict oil flow

    NASA Astrophysics Data System (ADS)

    Ludwig, Oswaldo; Nunes, Urbano; Araújo, Rui; Schnitman, Leizer; Lepikson, Herman Augusto

    2009-07-01

    This work introduces a new information-theoretic methodology for choosing variables and their time lags in a prediction setting, particularly when neural networks are used in non-linear modeling. The first contribution of this work is the Cross Entropy Function (XEF) proposed to select input variables and their lags in order to compose the input vector of black-box prediction models. The proposed XEF method is more appropriate than the usually applied Cross Correlation Function (XCF) when the relationship among the input and output signals comes from a non-linear dynamic system. The second contribution is a method that minimizes the Joint Conditional Entropy (JCE) between the input and output variables by means of a Genetic Algorithm (GA). The aim is to take into account the dependence among the input variables when selecting the most appropriate set of inputs for a prediction problem. In short, theses methods can be used to assist the selection of input training data that have the necessary information to predict the target data. The proposed methods are applied to a petroleum engineering problem; predicting oil production. Experimental results obtained with a real-world dataset are presented demonstrating the feasibility and effectiveness of the method.

  11. Automated design of infrared digital metamaterials by genetic algorithm

    NASA Astrophysics Data System (ADS)

    Sugino, Yuya; Ishikawa, Atsushi; Hayashi, Yasuhiko; Tsuruta, Kenji

    2017-08-01

    We demonstrate automatic design of infrared (IR) metamaterials using a genetic algorithm (GA) and experimentally characterize their IR properties. To implement the automated design scheme of the metamaterial structures, we adopt a digital metamaterial consisting of 7 × 7 Au nano-pixels with an area of 200 nm × 200 nm, and their placements are coded as binary genes in the GA optimization process. The GA combined with three-dimensional (3D) finite element method (FEM) simulation is developed and applied to automatically construct a digital metamaterial to exhibit pronounced plasmonic resonances at the target IR frequencies. Based on the numerical results, the metamaterials are fabricated on a Si substrate over an area of 1 mm × 1 mm by using an EB lithography, Cr/Au (2/20 nm) depositions, and liftoff process. In the FT-IR measurement, pronounced plasmonic responses of each metamaterial are clearly observed near the targeted frequencies, although the synthesized pixel arrangements of the metamaterials are seemingly random. The corresponding numerical simulations reveal the important resonant behavior of each pixel and their hybridized systems. Our approach is fully computer-aided without artificial manipulation, thus paving the way toward the novel device design for next-generation plasmonic device applications.

  12. Construction of Gene Regulatory Networks Using Recurrent Neural Networks and Swarm Intelligence.

    PubMed

    Khan, Abhinandan; Mandal, Sudip; Pal, Rajat Kumar; Saha, Goutam

    2016-01-01

    We have proposed a methodology for the reverse engineering of biologically plausible gene regulatory networks from temporal genetic expression data. We have used established information and the fundamental mathematical theory for this purpose. We have employed the Recurrent Neural Network formalism to extract the underlying dynamics present in the time series expression data accurately. We have introduced a new hybrid swarm intelligence framework for the accurate training of the model parameters. The proposed methodology has been first applied to a small artificial network, and the results obtained suggest that it can produce the best results available in the contemporary literature, to the best of our knowledge. Subsequently, we have implemented our proposed framework on experimental (in vivo) datasets. Finally, we have investigated two medium sized genetic networks (in silico) extracted from GeneNetWeaver, to understand how the proposed algorithm scales up with network size. Additionally, we have implemented our proposed algorithm with half the number of time points. The results indicate that a reduction of 50% in the number of time points does not have an effect on the accuracy of the proposed methodology significantly, with a maximum of just over 15% deterioration in the worst case.

  13. Optimization design of multiphase pump impeller based on combined genetic algorithm and boundary vortex flux diagnosis

    NASA Astrophysics Data System (ADS)

    Zhang, Jin-ya; Cai, Shu-jie; Li, Yong-jiang; Li, Yong-jiang; Zhang, Yong-xue

    2017-12-01

    A novel optimization design method for the multiphase pump impeller is proposed through combining the quasi-3D hydraulic design (Q3DHD), the boundary vortex flux (BVF) diagnosis, and the genetic algorithm (GA). The BVF diagnosis based on the Q3DHD is used to evaluate the objection function. Numerical simulations and hydraulic performance tests are carried out to compare the impeller designed only by the Q3DHD method and that optimized by the presented method. The comparisons of both the flow fields simulated under the same condition show that (1) the pressure distribution in the optimized impeller is more reasonable and the gas-liquid separation is more efficiently inhibited, (2) the scales of the gas pocket and the vortex decrease remarkably for the optimized impeller, (3) the unevenness of the BVF distributions near the shroud of the original impeller is effectively eliminated in the optimized impeller. The experimental results show that the differential pressure and the maximum efficiency of the optimized impeller are increased by 4% and 2.5%, respectively. Overall, the study indicates that the optimization design method proposed in this paper is feasible.

  14. In silico modelling of directed evolution: Implications for experimental design and stepwise evolution.

    PubMed

    Wedge, David C; Rowe, William; Kell, Douglas B; Knowles, Joshua

    2009-03-07

    We model the process of directed evolution (DE) in silico using genetic algorithms. Making use of the NK fitness landscape model, we analyse the effects of mutation rate, crossover and selection pressure on the performance of DE. A range of values of K, the epistatic interaction of the landscape, are considered, and high- and low-throughput modes of evolution are compared. Our findings suggest that for runs of or around ten generations' duration-as is typical in DE-there is little difference between the way in which DE needs to be configured in the high- and low-throughput regimes, nor across different degrees of landscape epistasis. In all cases, a high selection pressure (but not an extreme one) combined with a moderately high mutation rate works best, while crossover provides some benefit but only on the less rugged landscapes. These genetic algorithms were also compared with a "model-based approach" from the literature, which uses sequential fixing of the problem parameters based on fitting a linear model. Overall, we find that purely evolutionary techniques fare better than do model-based approaches across all but the smoothest landscapes.

  15. Computational discovery of pathway-level genetic vulnerabilities in non-small-cell lung cancer

    PubMed Central

    Young, Jonathan H.; Peyton, Michael; Seok Kim, Hyun; McMillan, Elizabeth; Minna, John D.; White, Michael A.; Marcotte, Edward M.

    2016-01-01

    Motivation: Novel approaches are needed for discovery of targeted therapies for non-small-cell lung cancer (NSCLC) that are specific to certain patients. Whole genome RNAi screening of lung cancer cell lines provides an ideal source for determining candidate drug targets. Results: Unsupervised learning algorithms uncovered patterns of differential vulnerability across lung cancer cell lines to loss of functionally related genes. Such genetic vulnerabilities represent candidate targets for therapy and are found to be involved in splicing, translation and protein folding. In particular, many NSCLC cell lines were especially sensitive to the loss of components of the LSm2-8 protein complex or the CCT/TRiC chaperonin. Different vulnerabilities were also found for different cell line subgroups. Furthermore, the predicted vulnerability of a single adenocarcinoma cell line to loss of the Wnt pathway was experimentally validated with screening of small-molecule Wnt inhibitors against an extensive cell line panel. Availability and implementation: The clustering algorithm is implemented in Python and is freely available at https://bitbucket.org/youngjh/nsclc_paper. Contact: marcotte@icmb.utexas.edu or jon.young@utexas.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:26755624

  16. Computational discovery of pathway-level genetic vulnerabilities in non-small-cell lung cancer.

    PubMed

    Young, Jonathan H; Peyton, Michael; Seok Kim, Hyun; McMillan, Elizabeth; Minna, John D; White, Michael A; Marcotte, Edward M

    2016-05-01

    Novel approaches are needed for discovery of targeted therapies for non-small-cell lung cancer (NSCLC) that are specific to certain patients. Whole genome RNAi screening of lung cancer cell lines provides an ideal source for determining candidate drug targets. Unsupervised learning algorithms uncovered patterns of differential vulnerability across lung cancer cell lines to loss of functionally related genes. Such genetic vulnerabilities represent candidate targets for therapy and are found to be involved in splicing, translation and protein folding. In particular, many NSCLC cell lines were especially sensitive to the loss of components of the LSm2-8 protein complex or the CCT/TRiC chaperonin. Different vulnerabilities were also found for different cell line subgroups. Furthermore, the predicted vulnerability of a single adenocarcinoma cell line to loss of the Wnt pathway was experimentally validated with screening of small-molecule Wnt inhibitors against an extensive cell line panel. The clustering algorithm is implemented in Python and is freely available at https://bitbucket.org/youngjh/nsclc_paper marcotte@icmb.utexas.edu or jon.young@utexas.edu Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.

  17. Combination of artificial neural network and genetic algorithm method for modeling of methylene blue adsorption onto wood sawdust from water samples.

    PubMed

    Khajeh, Mostafa; Sarafraz-Yazdi, Ali; Natavan, Zahra Bameri

    2016-03-01

    The aim of this research was to develop a low price and environmentally friendly adsorbent with abundant of source to remove methylene blue (MB) from water samples. Sawdust solid-phase extraction coupled with high-performance liquid chromatography was used for the extraction and determination of MB. In this study, an experimental data-based artificial neural network model is constructed to describe the performance of sawdust solid-phase extraction method for various operating conditions. The pH, time, amount of sawdust, and temperature were the input variables, while the percentage of extraction of MB was the output. The optimum operating condition was then determined by genetic algorithm method. The optimized conditions were obtained as follows: 11.5, 22.0 min, 0.3 g, and 26.0°C for pH of the solution, extraction time, amount of adsorbent, and temperature, respectively. Under these optimum conditions, the detection limit and relative standard deviation were 0.067 μg L(-1) and <2.4%, respectively. The Langmuir and Freundlich adsorption models were applied to describe the isotherm constant and for the removal and determination of MB from water samples. © The Author(s) 2013.

  18. Genetic algorithm optimized triply compensated pulses in NMR spectroscopy

    NASA Astrophysics Data System (ADS)

    Manu, V. S.; Veglia, Gianluigi

    2015-11-01

    Sensitivity and resolution in NMR experiments are affected by magnetic field inhomogeneities (of both external and RF), errors in pulse calibration, and offset effects due to finite length of RF pulses. To remedy these problems, built-in compensation mechanisms for these experimental imperfections are often necessary. Here, we propose a new family of phase-modulated constant-amplitude broadband pulses with high compensation for RF inhomogeneity and heteronuclear coupling evolution. These pulses were optimized using a genetic algorithm (GA), which consists in a global optimization method inspired by Nature's evolutionary processes. The newly designed π and π / 2 pulses belong to the 'type A' (or general rotors) symmetric composite pulses. These GA-optimized pulses are relatively short compared to other general rotors and can be used for excitation and inversion, as well as refocusing pulses in spin-echo experiments. The performance of the GA-optimized pulses was assessed in Magic Angle Spinning (MAS) solid-state NMR experiments using a crystalline U-13C, 15N NAVL peptide as well as U-13C, 15N microcrystalline ubiquitin. GA optimization of NMR pulse sequences opens a window for improving current experiments and designing new robust pulse sequences.

  19. Instruction-matrix-based genetic programming.

    PubMed

    Li, Gang; Wang, Jin Feng; Lee, Kin Hong; Leung, Kwong-Sak

    2008-08-01

    In genetic programming (GP), evolving tree nodes separately would reduce the huge solution space. However, tree nodes are highly interdependent with respect to their fitness. In this paper, we propose a new GP framework, namely, instruction-matrix (IM)-based GP (IMGP), to handle their interactions. IMGP maintains an IM to evolve tree nodes and subtrees separately. IMGP extracts program trees from an IM and updates the IM with the information of the extracted program trees. As the IM actually keeps most of the information of the schemata of GP and evolves the schemata directly, IMGP is effective and efficient. Our experimental results on benchmark problems have verified that IMGP is not only better than those of canonical GP in terms of the qualities of the solutions and the number of program evaluations, but they are also better than some of the related GP algorithms. IMGP can also be used to evolve programs for classification problems. The classifiers obtained have higher classification accuracies than four other GP classification algorithms on four benchmark classification problems. The testing errors are also comparable to or better than those obtained with well-known classifiers. Furthermore, an extended version, called condition matrix for rule learning, has been used successfully to handle multiclass classification problems.

  20. Finite element analysis and genetic algorithm optimization design for the actuator placement on a large adaptive structure

    NASA Astrophysics Data System (ADS)

    Sheng, Lizeng

    The dissertation focuses on one of the major research needs in the area of adaptive/intelligent/smart structures, the development and application of finite element analysis and genetic algorithms for optimal design of large-scale adaptive structures. We first review some basic concepts in finite element method and genetic algorithms, along with the research on smart structures. Then we propose a solution methodology for solving a critical problem in the design of a next generation of large-scale adaptive structures---optimal placements of a large number of actuators to control thermal deformations. After briefly reviewing the three most frequently used general approaches to derive a finite element formulation, the dissertation presents techniques associated with general shell finite element analysis using flat triangular laminated composite elements. The element used here has three nodes and eighteen degrees of freedom and is obtained by combining a triangular membrane element and a triangular plate bending element. The element includes the coupling effect between membrane deformation and bending deformation. The membrane element is derived from the linear strain triangular element using Cook's transformation. The discrete Kirchhoff triangular (DKT) element is used as the plate bending element. For completeness, a complete derivation of the DKT is presented. Geometrically nonlinear finite element formulation is derived for the analysis of adaptive structures under the combined thermal and electrical loads. Next, we solve the optimization problems of placing a large number of piezoelectric actuators to control thermal distortions in a large mirror in the presence of four different thermal loads. We then extend this to a multi-objective optimization problem of determining only one set of piezoelectric actuator locations that can be used to control the deformation in the same mirror under the action of any one of the four thermal loads. A series of genetic algorithms, GA Version 1, 2 and 3, were developed to find the optimal locations of piezoelectric actuators from the order of 1021 ˜ 1056 candidate placements. Introducing a variable population approach, we improve the flexibility of selection operation in genetic algorithms. Incorporating mutation and hill climbing into micro-genetic algorithms, we are able to develop a more efficient genetic algorithm. Through extensive numerical experiments, we find that the design search space for the optimal placements of a large number of actuators is highly multi-modal and that the most distinct nature of genetic algorithms is their robustness. They give results that are random but with only a slight variability. The genetic algorithms can be used to get adequate solution using a limited number of evaluations. To get the highest quality solution, multiple runs including different random seed generators are necessary. The investigation time can be significantly reduced using a very coarse grain parallel computing. Overall, the methodology of using finite element analysis and genetic algorithm optimization provides a robust solution approach for the challenging problem of optimal placements of a large number of actuators in the design of next generation of adaptive structures.

  1. Selecting materialized views using random algorithm

    NASA Astrophysics Data System (ADS)

    Zhou, Lijuan; Hao, Zhongxiao; Liu, Chi

    2007-04-01

    The data warehouse is a repository of information collected from multiple possibly heterogeneous autonomous distributed databases. The information stored at the data warehouse is in form of views referred to as materialized views. The selection of the materialized views is one of the most important decisions in designing a data warehouse. Materialized views are stored in the data warehouse for the purpose of efficiently implementing on-line analytical processing queries. The first issue for the user to consider is query response time. So in this paper, we develop algorithms to select a set of views to materialize in data warehouse in order to minimize the total view maintenance cost under the constraint of a given query response time. We call it query_cost view_ selection problem. First, cost graph and cost model of query_cost view_ selection problem are presented. Second, the methods for selecting materialized views by using random algorithms are presented. The genetic algorithm is applied to the materialized views selection problem. But with the development of genetic process, the legal solution produced become more and more difficult, so a lot of solutions are eliminated and producing time of the solutions is lengthened in genetic algorithm. Therefore, improved algorithm has been presented in this paper, which is the combination of simulated annealing algorithm and genetic algorithm for the purpose of solving the query cost view selection problem. Finally, in order to test the function and efficiency of our algorithms experiment simulation is adopted. The experiments show that the given methods can provide near-optimal solutions in limited time and works better in practical cases. Randomized algorithms will become invaluable tools for data warehouse evolution.

  2. Ortho Image and DTM Generation with Intelligent Methods

    NASA Astrophysics Data System (ADS)

    Bagheri, H.; Sadeghian, S.

    2013-10-01

    Nowadays the artificial intelligent algorithms has considered in GIS and remote sensing. Genetic algorithm and artificial neural network are two intelligent methods that are used for optimizing of image processing programs such as edge extraction and etc. these algorithms are very useful for solving of complex program. In this paper, the ability and application of genetic algorithm and artificial neural network in geospatial production process like geometric modelling of satellite images for ortho photo generation and height interpolation in raster Digital Terrain Model production process is discussed. In first, the geometric potential of Ikonos-2 and Worldview-2 with rational functions, 2D & 3D polynomials were tested. Also comprehensive experiments have been carried out to evaluate the viability of the genetic algorithm for optimization of rational function, 2D & 3D polynomials. Considering the quality of Ground Control Points, the accuracy (RMSE) with genetic algorithm and 3D polynomials method for Ikonos-2 Geo image was 0.508 pixel sizes and the accuracy (RMSE) with GA algorithm and rational function method for Worldview-2 image was 0.930 pixel sizes. For more another optimization artificial intelligent methods, neural networks were used. With the use of perceptron network in Worldview-2 image, a result of 0.84 pixel sizes with 4 neurons in middle layer was gained. The final conclusion was that with artificial intelligent algorithms it is possible to optimize the existing models and have better results than usual ones. Finally the artificial intelligence methods, like genetic algorithms as well as neural networks, were examined on sample data for optimizing interpolation and for generating Digital Terrain Models. The results then were compared with existing conventional methods and it appeared that these methods have a high capacity in heights interpolation and that using these networks for interpolating and optimizing the weighting methods based on inverse distance leads to a high accurate estimation of heights.

  3. Vibration suppression of a piezo-equipped cylindrical shell in a broad-band frequency domain

    NASA Astrophysics Data System (ADS)

    Loghmani, Ali; Danesh, Mohammad; Kwak, Moon K.; Keshmiri, Mehdi

    2017-12-01

    This paper focuses on the dynamic modeling of a cylindrical shell equipped with piezoceramic sensors and actuators, as well as the design of a broad band multi-input and multi-output linear quadratic Gaussian controller for the suppression of vibrations. The optimal locations of actuators are derived by Genetic Algorithm (GA) to effectively control the specific structural modes of the cylinder. The dynamic model is derived based on the Sanders shell theory and the energy approach for both the cylinder and the piezoelectric transducers, all of which reflect the piezoelectric effect. The natural vibration characteristics of the cylindrical shell are investigated both theoretically and experimentally. The theoretical predictions are in good agreement with the experimental results. Then, the broad band multi-input and multi-output linear quadratic Gaussian controller was designed and applied to the test article. An active vibration control experiment is carried out on the cylindrical shell and the digital control system is used to implement the proposed control algorithm. The experimental results show that vibrations of the cylindrical shell can be suppressed by the piezoceramic sensors and actuators along with the proposed controller. The optimal location of the actuators makes the proposed control system more efficient than other configurations.

  4. Sensitivity Analysis of Genetic Algorithm Parameters for Optimal Groundwater Monitoring Network Design

    NASA Astrophysics Data System (ADS)

    Abdeh-Kolahchi, A.; Satish, M.; Datta, B.

    2004-05-01

    A state art groundwater monitoring network design is introduced. The method combines groundwater flow and transport results with optimization Genetic Algorithm (GA) to identify optimal monitoring well locations. Optimization theory uses different techniques to find a set of parameter values that minimize or maximize objective functions. The suggested groundwater optimal monitoring network design is based on the objective of maximizing the probability of tracking a transient contamination plume by determining sequential monitoring locations. The MODFLOW and MT3DMS models included as separate modules within the Groundwater Modeling System (GMS) are used to develop three dimensional groundwater flow and contamination transport simulation. The groundwater flow and contamination simulation results are introduced as input to the optimization model, using Genetic Algorithm (GA) to identify the groundwater optimal monitoring network design, based on several candidate monitoring locations. The groundwater monitoring network design model is used Genetic Algorithms with binary variables representing potential monitoring location. As the number of decision variables and constraints increase, the non-linearity of the objective function also increases which make difficulty to obtain optimal solutions. The genetic algorithm is an evolutionary global optimization technique, which is capable of finding the optimal solution for many complex problems. In this study, the GA approach capable of finding the global optimal solution to a groundwater monitoring network design problem involving 18.4X 1018 feasible solutions will be discussed. However, to ensure the efficiency of the solution process and global optimality of the solution obtained using GA, it is necessary that appropriate GA parameter values be specified. The sensitivity analysis of genetic algorithms parameters such as random number, crossover probability, mutation probability, and elitism are discussed for solution of monitoring network design.

  5. JavaGenes and Condor: Cycle-Scavenging Genetic Algorithms

    NASA Technical Reports Server (NTRS)

    Globus, Al; Langhirt, Eric; Livny, Miron; Ramamurthy, Ravishankar; Soloman, Marvin; Traugott, Steve

    2000-01-01

    A genetic algorithm code, JavaGenes, was written in Java and used to evolve pharmaceutical drug molecules and digital circuits. JavaGenes was run under the Condor cycle-scavenging batch system managing 100-170 desktop SGI workstations. Genetic algorithms mimic biological evolution by evolving solutions to problems using crossover and mutation. While most genetic algorithms evolve strings or trees, JavaGenes evolves graphs representing (currently) molecules and circuits. Java was chosen as the implementation language because the genetic algorithm requires random splitting and recombining of graphs, a complex data structure manipulation with ample opportunities for memory leaks, loose pointers, out-of-bound indices, and other hard to find bugs. Java garbage-collection memory management, lack of pointer arithmetic, and array-bounds index checking prevents these bugs from occurring, substantially reducing development time. While a run-time performance penalty must be paid, the only unacceptable performance we encountered was using standard Java serialization to checkpoint and restart the code. This was fixed by a two-day implementation of custom checkpointing. JavaGenes is minimally integrated with Condor; in other words, JavaGenes must do its own checkpointing and I/O redirection. A prototype Java-aware version of Condor was developed using standard Java serialization for checkpointing. For the prototype to be useful, standard Java serialization must be significantly optimized. JavaGenes is approximately 8700 lines of code and a few thousand JavaGenes jobs have been run. Most jobs ran for a few days. Results include proof that genetic algorithms can evolve directed and undirected graphs, development of a novel crossover operator for graphs, a paper in the journal Nanotechnology, and another paper in preparation.

  6. Incremental cost-effectiveness of algorithm-driven genetic testing versus no testing for Maturity Onset Diabetes of the Young (MODY) in Singapore.

    PubMed

    Nguyen, Hai Van; Finkelstein, Eric Andrew; Mital, Shweta; Gardner, Daphne Su-Lyn

    2017-11-01

    Offering genetic testing for Maturity Onset Diabetes of the Young (MODY) to all young patients with type 2 diabetes has been shown to be not cost-effective. This study tests whether a novel algorithm-driven genetic testing strategy for MODY is incrementally cost-effective relative to the setting of no testing. A decision tree was constructed to estimate the costs and effectiveness of the algorithm-driven MODY testing strategy and a strategy of no genetic testing over a 30-year time horizon from a payer's perspective. The algorithm uses glutamic acid decarboxylase (GAD) antibody testing (negative antibodies), age of onset of diabetes (<45 years) and body mass index (<25 kg/m 2 if diagnosed >30 years) to stratify the population of patients with diabetes into three subgroups, and testing for MODY only among the subgroup most likely to have the mutation. Singapore-specific costs and prevalence of MODY obtained from local studies and utility values sourced from the literature are used to populate the model. The algorithm-driven MODY testing strategy has an incremental cost-effectiveness ratio of US$93 663 per quality-adjusted life year relative to the no testing strategy. If the price of genetic testing falls from US$1050 to US$530 (a 50% decrease), it will become cost-effective. Our proposed algorithm-driven testing strategy for MODY is not yet cost-effective based on established benchmarks. However, as genetic testing prices continue to fall, this strategy is likely to become cost-effective in the near future. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  7. Genetic Algorithms for Multiple-Choice Problems

    NASA Astrophysics Data System (ADS)

    Aickelin, Uwe

    2010-04-01

    This thesis investigates the use of problem-specific knowledge to enhance a genetic algorithm approach to multiple-choice optimisation problems.It shows that such information can significantly enhance performance, but that the choice of information and the way it is included are important factors for success.Two multiple-choice problems are considered.The first is constructing a feasible nurse roster that considers as many requests as possible.In the second problem, shops are allocated to locations in a mall subject to constraints and maximising the overall income.Genetic algorithms are chosen for their well-known robustness and ability to solve large and complex discrete optimisation problems.However, a survey of the literature reveals room for further research into generic ways to include constraints into a genetic algorithm framework.Hence, the main theme of this work is to balance feasibility and cost of solutions.In particular, co-operative co-evolution with hierarchical sub-populations, problem structure exploiting repair schemes and indirect genetic algorithms with self-adjusting decoder functions are identified as promising approaches.The research starts by applying standard genetic algorithms to the problems and explaining the failure of such approaches due to epistasis.To overcome this, problem-specific information is added in a variety of ways, some of which are designed to increase the number of feasible solutions found whilst others are intended to improve the quality of such solutions.As well as a theoretical discussion as to the underlying reasons for using each operator,extensive computational experiments are carried out on a variety of data.These show that the indirect approach relies less on problem structure and hence is easier to implement and superior in solution quality.

  8. Genetic programming based models in plant tissue culture: An addendum to traditional statistical approach.

    PubMed

    Mridula, Meenu R; Nair, Ashalatha S; Kumar, K Satheesh

    2018-02-01

    In this paper, we compared the efficacy of observation based modeling approach using a genetic algorithm with the regular statistical analysis as an alternative methodology in plant research. Preliminary experimental data on in vitro rooting was taken for this study with an aim to understand the effect of charcoal and naphthalene acetic acid (NAA) on successful rooting and also to optimize the two variables for maximum result. Observation-based modelling, as well as traditional approach, could identify NAA as a critical factor in rooting of the plantlets under the experimental conditions employed. Symbolic regression analysis using the software deployed here optimised the treatments studied and was successful in identifying the complex non-linear interaction among the variables, with minimalistic preliminary data. The presence of charcoal in the culture medium has a significant impact on root generation by reducing basal callus mass formation. Such an approach is advantageous for establishing in vitro culture protocols as these models will have significant potential for saving time and expenditure in plant tissue culture laboratories, and it further reduces the need for specialised background.

  9. Constrained minimization of smooth functions using a genetic algorithm

    NASA Technical Reports Server (NTRS)

    Moerder, Daniel D.; Pamadi, Bandu N.

    1994-01-01

    The use of genetic algorithms for minimization of differentiable functions that are subject to differentiable constraints is considered. A technique is demonstrated for converting the solution of the necessary conditions for a constrained minimum into an unconstrained function minimization. This technique is extended as a global constrained optimization algorithm. The theory is applied to calculating minimum-fuel ascent control settings for an energy state model of an aerospace plane.

  10. In silico prediction of toxicity of phenols to Tetrahymena pyriformis by using genetic algorithm and decision tree-based modeling approach.

    PubMed

    Abbasitabar, Fatemeh; Zare-Shahabadi, Vahid

    2017-04-01

    Risk assessment of chemicals is an important issue in environmental protection; however, there is a huge lack of experimental data for a large number of end-points. The experimental determination of toxicity of chemicals involves high costs and time-consuming process. In silico tools such as quantitative structure-toxicity relationship (QSTR) models, which are constructed on the basis of computational molecular descriptors, can predict missing data for toxic end-points for existing or even not yet synthesized chemicals. Phenol derivatives are known to be aquatic pollutants. With this background, we aimed to develop an accurate and reliable QSTR model for the prediction of toxicity of 206 phenols to Tetrahymena pyriformis. A multiple linear regression (MLR)-based QSTR was obtained using a powerful descriptor selection tool named Memorized_ACO algorithm. Statistical parameters of the model were 0.72 and 0.68 for R training 2 and R test 2 , respectively. To develop a high-quality QSTR model, classification and regression tree (CART) was employed. Two approaches were considered: (1) phenols were classified into different modes of action using CART and (2) the phenols in the training set were partitioned to several subsets by a tree in such a manner that in each subset, a high-quality MLR could be developed. For the first approach, the statistical parameters of the resultant QSTR model were improved to 0.83 and 0.75 for R training 2 and R test 2 , respectively. Genetic algorithm was employed in the second approach to obtain an optimal tree, and it was shown that the final QSTR model provided excellent prediction accuracy for the training and test sets (R training 2 and R test 2 were 0.91 and 0.93, respectively). The mean absolute error for the test set was computed as 0.1615. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Real Time Optima Tracking Using Harvesting Models of the Genetic Algorithm

    NASA Technical Reports Server (NTRS)

    Baskaran, Subbiah; Noever, D.

    1999-01-01

    Tracking optima in real time propulsion control, particularly for non-stationary optimization problems is a challenging task. Several approaches have been put forward for such a study including the numerical method called the genetic algorithm. In brief, this approach is built upon Darwinian-style competition between numerical alternatives displayed in the form of binary strings, or by analogy to 'pseudogenes'. Breeding of improved solution is an often cited parallel to natural selection in.evolutionary or soft computing. In this report we present our results of applying a novel model of a genetic algorithm for tracking optima in propulsion engineering and in real time control. We specialize the algorithm to mission profiling and planning optimizations, both to select reduced propulsion needs through trajectory planning and to explore time or fuel conservation strategies.

  12. Study of genetic direct search algorithms for function optimization

    NASA Technical Reports Server (NTRS)

    Zeigler, B. P.

    1974-01-01

    The results are presented of a study to determine the performance of genetic direct search algorithms in solving function optimization problems arising in the optimal and adaptive control areas. The findings indicate that: (1) genetic algorithms can outperform standard algorithms in multimodal and/or noisy optimization situations, but suffer from lack of gradient exploitation facilities when gradient information can be utilized to guide the search. (2) For large populations, or low dimensional function spaces, mutation is a sufficient operator. However for small populations or high dimensional functions, crossover applied in about equal frequency with mutation is an optimum combination. (3) Complexity, in terms of storage space and running time, is significantly increased when population size is increased or the inversion operator, or the second level adaptation routine is added to the basic structure.

  13. Modeling Self-Healing of Concrete Using Hybrid Genetic Algorithm–Artificial Neural Network

    PubMed Central

    Ramadan Suleiman, Ahmed; Nehdi, Moncef L.

    2017-01-01

    This paper presents an approach to predicting the intrinsic self-healing in concrete using a hybrid genetic algorithm–artificial neural network (GA–ANN). A genetic algorithm was implemented in the network as a stochastic optimizing tool for the initial optimal weights and biases. This approach can assist the network in achieving a global optimum and avoid the possibility of the network getting trapped at local optima. The proposed model was trained and validated using an especially built database using various experimental studies retrieved from the open literature. The model inputs include the cement content, water-to-cement ratio (w/c), type and dosage of supplementary cementitious materials, bio-healing materials, and both expansive and crystalline additives. Self-healing indicated by means of crack width is the model output. The results showed that the proposed GA–ANN model is capable of capturing the complex effects of various self-healing agents (e.g., biochemical material, silica-based additive, expansive and crystalline components) on the self-healing performance in cement-based materials. PMID:28772495

  14. Convergence properties of simple genetic algorithms

    NASA Technical Reports Server (NTRS)

    Bethke, A. D.; Zeigler, B. P.; Strauss, D. M.

    1974-01-01

    The essential parameters determining the behaviour of genetic algorithms were investigated. Computer runs were made while systematically varying the parameter values. Results based on the progress curves obtained from these runs are presented along with results based on the variability of the population as the run progresses.

  15. Estimation of radiative and conductive properties of a semitransparent medium using genetic algorithms

    NASA Astrophysics Data System (ADS)

    Braiek, A.; Adili, A.; Albouchi, F.; Karkri, M.; Ben Nasrallah, S.

    2016-06-01

    The aim of this work is to simultaneously identify the conductive and radiative parameters of a semitransparent sample using a photothermal method associated with an inverse problem. The identification of the conductive and radiative proprieties is performed by the minimization of an objective function that represents the errors between calculated temperature and measured signal. The calculated temperature is obtained from a theoretical model built with the thermal quadrupole formalism. Measurement is obtained in the rear face of the sample whose front face is excited by a crenel of heat flux. For identification procedure, a genetic algorithm is developed and used. The genetic algorithm is a useful tool in the simultaneous estimation of correlated or nearly correlated parameters, which can be a limiting factor for the gradient-based methods. The results of the identification procedure show the efficiency and the stability of the genetic algorithm to simultaneously estimate the conductive and radiative properties of clear glass.

  16. An application of CART algorithm in genetics: IGFs and cGH polymorphisms in Japanese quail

    NASA Astrophysics Data System (ADS)

    Kaplan, Selçuk

    2017-04-01

    The avian insulin-like growth factor-1 (IGFs) and avian growth hormone (cGH) genes are the most important genes that can affect bird performance traits because of its important function in growth and metabolism. Understanding the molecular genetic basis of variation in growth-related traits is of importance for continued improvement and increased rates of genetic gain. The objective of the present study was to identify polymorphisms of cGH and IGFs genes in Japanese quail using conventional least square method (LSM) and CART algorithm. Therefore, this study was aimed to demonstrate at determining the polymorphisms of two genes related growth characteristics via CART algorithm. A simulated data set was generated to analyze by adhering the results of some poultry genetic studies which it includes live weights at 5 weeks of age, 3 alleles and 6 genotypes of cGH and 2 alleles and 3 genotypes of IGFs. As a result, it has been determined that the CART algorithm has some advantages as for that LSM.

  17. Application of artificial intelligence to search ground-state geometry of clusters

    NASA Astrophysics Data System (ADS)

    Lemes, Maurício Ruv; Marim, L. R.; dal Pino, A.

    2002-08-01

    We introduce a global optimization procedure, the neural-assisted genetic algorithm (NAGA). It combines the power of an artificial neural network (ANN) with the versatility of the genetic algorithm. This method is suitable to solve optimization problems that depend on some kind of heuristics to limit the search space. If a reasonable amount of data is available, the ANN can ``understand'' the problem and provide the genetic algorithm with a selected population of elements that will speed up the search for the optimum solution. We tested the method in a search for the ground-state geometry of silicon clusters. We trained the ANN with information about the geometry and energetics of small silicon clusters. Next, the ANN learned how to restrict the configurational space for larger silicon clusters. For Si10 and Si20, we noticed that the NAGA is at least three times faster than the ``pure'' genetic algorithm. As the size of the cluster increases, it is expected that the gain in terms of time will increase as well.

  18. Application of genetic algorithms to focal mechanism determination

    NASA Astrophysics Data System (ADS)

    Kobayashi, Reiji; Nakanishi, Ichiro

    1994-04-01

    Genetic algorithms are a new class of methods for global optimization. They resemble Monte Carlo techniques, but search for solutions more efficiently than uniform Monte Carlo sampling. In the field of geophysics, genetic algorithms have recently been used to solve some non-linear inverse problems (e.g., earthquake location, waveform inversion, migration velocity estimation). We present an application of genetic algorithms to focal mechanism determination from first-motion polarities of P-waves and apply our method to two recent large events, the Kushiro-oki earthquake of January 15, 1993 and the SW Hokkaido (Japan Sea) earthquake of July 12, 1993. Initial solution and curvature information of the objective function that gradient methods need are not required in our approach. Moreover globally optimal solutions can be efficiently obtained. Calculation of polarities based on double-couple models is the most time-consuming part of the source mechanism determination. The amount of calculations required by the method designed in this study is much less than that of previous grid search methods.

  19. Optimized design on condensing tubes high-speed TIG welding technology magnetic control based on genetic algorithm

    NASA Astrophysics Data System (ADS)

    Lu, Lin; Chang, Yunlong; Li, Yingmin; Lu, Ming

    2013-05-01

    An orthogonal experiment was conducted by the means of multivariate nonlinear regression equation to adjust the influence of external transverse magnetic field and Ar flow rate on welding quality in the process of welding condenser pipe by high-speed argon tungsten-arc welding (TIG for short). The magnetic induction and flow rate of Ar gas were used as optimum variables, and tensile strength of weld was set to objective function on the base of genetic algorithm theory, and then an optimal design was conducted. According to the request of physical production, the optimum variables were restrained. The genetic algorithm in the MATLAB was used for computing. A comparison between optimum results and experiment parameters was made. The results showed that the optimum technologic parameters could be chosen by the means of genetic algorithm with the conditions of excessive optimum variables in the process of high-speed welding. And optimum technologic parameters of welding coincided with experiment results.

  20. Optimal sensor placement for spatial lattice structure based on genetic algorithms

    NASA Astrophysics Data System (ADS)

    Liu, Wei; Gao, Wei-cheng; Sun, Yi; Xu, Min-jian

    2008-10-01

    Optimal sensor placement technique plays a key role in structural health monitoring of spatial lattice structures. This paper considers the problem of locating sensors on a spatial lattice structure with the aim of maximizing the data information so that structural dynamic behavior can be fully characterized. Based on the criterion of optimal sensor placement for modal test, an improved genetic algorithm is introduced to find the optimal placement of sensors. The modal strain energy (MSE) and the modal assurance criterion (MAC) have been taken as the fitness function, respectively, so that three placement designs were produced. The decimal two-dimension array coding method instead of binary coding method is proposed to code the solution. Forced mutation operator is introduced when the identical genes appear via the crossover procedure. A computational simulation of a 12-bay plain truss model has been implemented to demonstrate the feasibility of the three optimal algorithms above. The obtained optimal sensor placements using the improved genetic algorithm are compared with those gained by exiting genetic algorithm using the binary coding method. Further the comparison criterion based on the mean square error between the finite element method (FEM) mode shapes and the Guyan expansion mode shapes identified by data-driven stochastic subspace identification (SSI-DATA) method are employed to demonstrate the advantage of the different fitness function. The results showed that some innovations in genetic algorithm proposed in this paper can enlarge the genes storage and improve the convergence of the algorithm. More importantly, the three optimal sensor placement methods can all provide the reliable results and identify the vibration characteristics of the 12-bay plain truss model accurately.

  1. AccuTyping: new algorithms for automated analysis of data from high-throughput genotyping with oligonucleotide microarrays

    PubMed Central

    Hu, Guohong; Wang, Hui-Yun; Greenawalt, Danielle M.; Azaro, Marco A.; Luo, Minjie; Tereshchenko, Irina V.; Cui, Xiangfeng; Yang, Qifeng; Gao, Richeng; Shen, Li; Li, Honghua

    2006-01-01

    Microarray-based analysis of single nucleotide polymorphisms (SNPs) has many applications in large-scale genetic studies. To minimize the influence of experimental variation, microarray data usually need to be processed in different aspects including background subtraction, normalization and low-signal filtering before genotype determination. Although many algorithms are sophisticated for these purposes, biases are still present. In the present paper, new algorithms for SNP microarray data analysis and the software, AccuTyping, developed based on these algorithms are described. The algorithms take advantage of a large number of SNPs included in each assay, and the fact that the top and bottom 20% of SNPs can be safely treated as homozygous after sorting based on their ratios between the signal intensities. These SNPs are then used as controls for color channel normalization and background subtraction. Genotype calls are made based on the logarithms of signal intensity ratios using two cutoff values, which were determined after training the program with a dataset of ∼160 000 genotypes and validated by non-microarray methods. AccuTyping was used to determine >300 000 genotypes of DNA and sperm samples. The accuracy was shown to be >99%. AccuTyping can be downloaded from . PMID:16982644

  2. Neural system for heartbeats recognition using genetically integrated ensemble of classifiers.

    PubMed

    Osowski, Stanislaw; Siwek, Krzysztof; Siroic, Robert

    2011-03-01

    This paper presents the application of genetic algorithm for the integration of neural classifiers combined in the ensemble for the accurate recognition of heartbeat types on the basis of ECG registration. The idea presented in this paper is that using many classifiers arranged in the form of ensemble leads to the increased accuracy of the recognition. In such ensemble the important problem is the integration of all classifiers into one effective classification system. This paper proposes the use of genetic algorithm. It was shown that application of the genetic algorithm is very efficient and allows to reduce significantly the total error of heartbeat recognition. This was confirmed by the numerical experiments performed on the MIT BIH Arrhythmia Database. Copyright © 2011 Elsevier Ltd. All rights reserved.

  3. Astrophysical data mining with GPU. A case study: Genetic classification of globular clusters

    NASA Astrophysics Data System (ADS)

    Cavuoti, S.; Garofalo, M.; Brescia, M.; Paolillo, M.; Pescape', A.; Longo, G.; Ventre, G.

    2014-01-01

    We present a multi-purpose genetic algorithm, designed and implemented with GPGPU/CUDA parallel computing technology. The model was derived from our CPU serial implementation, named GAME (Genetic Algorithm Model Experiment). It was successfully tested and validated on the detection of candidate Globular Clusters in deep, wide-field, single band HST images. The GPU version of GAME will be made available to the community by integrating it into the web application DAMEWARE (DAta Mining Web Application REsource, http://dame.dsf.unina.it/beta_info.html), a public data mining service specialized on massive astrophysical data. Since genetic algorithms are inherently parallel, the GPGPU computing paradigm leads to a speedup of a factor of 200× in the training phase with respect to the CPU based version.

  4. Prioritizing the Components of Vulnerability: A Genetic Algorithm Minimization of Flood Risk

    NASA Astrophysics Data System (ADS)

    Bongolan, Vena Pearl; Ballesteros, Florencio; Baritua, Karessa Alexandra; Junne Santos, Marie

    2013-04-01

    We define a flood resistant city as an optimal arrangement of communities according to their traits, with the goal of minimizing the flooding vulnerability via a genetic algorithm. We prioritize the different components of flooding vulnerability, giving each component a weight, thus expressing vulnerability as a weighted sum. This serves as the fitness function for the genetic algorithm. We also allowed non-linear interactions among related but independent components, viz, poverty and mortality rate, and literacy and radio/ tv penetration. The designs produced reflect the relative importance of the components, and we observed a synchronicity between the interacting components, giving us a more consistent design.

  5. Algorithmic Trading with Developmental and Linear Genetic Programming

    NASA Astrophysics Data System (ADS)

    Wilson, Garnett; Banzhaf, Wolfgang

    A developmental co-evolutionary genetic programming approach (PAM DGP) and a standard linear genetic programming (LGP) stock trading systemare applied to a number of stocks across market sectors. Both GP techniques were found to be robust to market fluctuations and reactive to opportunities associated with stock price rise and fall, with PAMDGP generating notably greater profit in some stock trend scenarios. Both algorithms were very accurate at buying to achieve profit and selling to protect assets, while exhibiting bothmoderate trading activity and the ability to maximize or minimize investment as appropriate. The content of the trading rules produced by both algorithms are also examined in relation to stock price trend scenarios.

  6. Supervised chaos genetic algorithm based state of charge determination for LiFePO4 batteries in electric vehicles

    NASA Astrophysics Data System (ADS)

    Shen, Yanqing

    2018-04-01

    LiFePO4 battery is developed rapidly in electric vehicle, whose safety and functional capabilities are influenced greatly by the evaluation of available cell capacity. Added with adaptive switch mechanism, this paper advances a supervised chaos genetic algorithm based state of charge determination method, where a combined state space model is employed to simulate battery dynamics. The method is validated by the experiment data collected from battery test system. Results indicate that the supervised chaos genetic algorithm based state of charge determination method shows great performance with less computation complexity and is little influenced by the unknown initial cell state.

  7. Artificial intelligence programming with LabVIEW: genetic algorithms for instrumentation control and optimization.

    PubMed

    Moore, J H

    1995-06-01

    A genetic algorithm for instrumentation control and optimization was developed using the LabVIEW graphical programming environment. The usefulness of this methodology for the optimization of a closed loop control instrument is demonstrated with minimal complexity and the programming is presented in detail to facilitate its adaptation to other LabVIEW applications. Closed loop control instruments have variety of applications in the biomedical sciences including the regulation of physiological processes such as blood pressure. The program presented here should provide a useful starting point for those wishing to incorporate genetic algorithm approaches to LabVIEW mediated optimization of closed loop control instruments.

  8. An Efficient Functional Test Generation Method For Processors Using Genetic Algorithms

    NASA Astrophysics Data System (ADS)

    Hudec, Ján; Gramatová, Elena

    2015-07-01

    The paper presents a new functional test generation method for processors testing based on genetic algorithms and evolutionary strategies. The tests are generated over an instruction set architecture and a processor description. Such functional tests belong to the software-oriented testing. Quality of the tests is evaluated by code coverage of the processor description using simulation. The presented test generation method uses VHDL models of processors and the professional simulator ModelSim. The rules, parameters and fitness functions were defined for various genetic algorithms used in automatic test generation. Functionality and effectiveness were evaluated using the RISC type processor DP32.

  9. Particle swarm optimization - Genetic algorithm (PSOGA) on linear transportation problem

    NASA Astrophysics Data System (ADS)

    Rahmalia, Dinita

    2017-08-01

    Linear Transportation Problem (LTP) is the case of constrained optimization where we want to minimize cost subject to the balance of the number of supply and the number of demand. The exact method such as northwest corner, vogel, russel, minimal cost have been applied at approaching optimal solution. In this paper, we use heurisitic like Particle Swarm Optimization (PSO) for solving linear transportation problem at any size of decision variable. In addition, we combine mutation operator of Genetic Algorithm (GA) at PSO to improve optimal solution. This method is called Particle Swarm Optimization - Genetic Algorithm (PSOGA). The simulations show that PSOGA can improve optimal solution resulted by PSO.

  10. Fast optimization of glide vehicle reentry trajectory based on genetic algorithm

    NASA Astrophysics Data System (ADS)

    Jia, Jun; Dong, Ruixing; Yuan, Xuejun; Wang, Chuangwei

    2018-02-01

    An optimization method of reentry trajectory based on genetic algorithm is presented to meet the need of reentry trajectory optimization for glide vehicle. The dynamic model for the glide vehicle during reentry period is established. Considering the constraints of heat flux, dynamic pressure, overload etc., the optimization of reentry trajectory is investigated by utilizing genetic algorithm. The simulation shows that the method presented by this paper is effective for the optimization of reentry trajectory of glide vehicle. The efficiency and speed of this method is comparative with the references. Optimization results meet all constraints, and the on-line fast optimization is potential by pre-processing the offline samples.

  11. On Directly Solving SCHRÖDINGER Equation for H+2 Ion by Genetic Algorithm

    NASA Astrophysics Data System (ADS)

    Saha, Rajendra; Bhattacharyya, S. P.

    Schrödinger equation (SE) is sought to be solved directly for the ground state of H+2 ion by invoking genetic algorithm (GA). In one approach the internuclear distance (R) is kept fixed, the corresponding electronic SE for H+2 is solved by GA at each R and the full potential energy curve (PEC) is constructed. The minimum of the PEC is then located giving Ve and Re. Alternatively, Ve and Re are located in a single run by allowing R to vary simultaneously while solving the electronic SE by genetic algorithm. The performance patterns of the two strategies are compared.

  12. Applying a Genetic Algorithm to Reconfigurable Hardware

    NASA Technical Reports Server (NTRS)

    Wells, B. Earl; Weir, John; Trevino, Luis; Patrick, Clint; Steincamp, Jim

    2004-01-01

    This paper investigates the feasibility of applying genetic algorithms to solve optimization problems that are implemented entirely in reconfgurable hardware. The paper highlights the pe$ormance/design space trade-offs that must be understood to effectively implement a standard genetic algorithm within a modem Field Programmable Gate Array, FPGA, reconfgurable hardware environment and presents a case-study where this stochastic search technique is applied to standard test-case problems taken from the technical literature. In this research, the targeted FPGA-based platform and high-level design environment was the Starbridge Hypercomputing platform, which incorporates multiple Xilinx Virtex II FPGAs, and the Viva TM graphical hardware description language.

  13. Genetic algorithms and their use in Geophysical Problems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Parker, Paul B.

    1999-04-01

    Genetic algorithms (GAs), global optimization methods that mimic Darwinian evolution are well suited to the nonlinear inverse problems of geophysics. A standard genetic algorithm selects the best or ''fittest'' models from a ''population'' and then applies operators such as crossover and mutation in order to combine the most successful characteristics of each model and produce fitter models. More sophisticated operators have been developed, but the standard GA usually provides a robust and efficient search. Although the choice of parameter settings such as crossover and mutation rate may depend largely on the type of problem being solved, numerous results show thatmore » certain parameter settings produce optimal performance for a wide range of problems and difficulties. In particular, a low (about half of the inverse of the population size) mutation rate is crucial for optimal results, but the choice of crossover method and rate do not seem to affect performance appreciably. Optimal efficiency is usually achieved with smaller (< 50) populations. Lastly, tournament selection appears to be the best choice of selection methods due to its simplicity and its autoscaling properties. However, if a proportional selection method is used such as roulette wheel selection, fitness scaling is a necessity, and a high scaling factor (> 2.0) should be used for the best performance. Three case studies are presented in which genetic algorithms are used to invert for crustal parameters. The first is an inversion for basement depth at Yucca mountain using gravity data, the second an inversion for velocity structure in the crust of the south island of New Zealand using receiver functions derived from teleseismic events, and the third is a similar receiver function inversion for crustal velocities beneath the Mendocino Triple Junction region of Northern California. The inversions demonstrate that genetic algorithms are effective in solving problems with reasonably large numbers of free parameters and with computationally expensive objective function calculations. More sophisticated techniques are presented for special problems. Niching and island model algorithms are introduced as methods to find multiple, distinct solutions to the nonunique problems that are typically seen in geophysics. Finally, hybrid algorithms are investigated as a way to improve the efficiency of the standard genetic algorithm.« less

  14. Genetic algorithms and their use in geophysical problems

    NASA Astrophysics Data System (ADS)

    Parker, Paul Bradley

    Genetic algorithms (GAs), global optimization methods that mimic Darwinian evolution are well suited to the nonlinear inverse problems of geophysics. A standard genetic algorithm selects the best or "fittest" models from a "population" and then applies operators such as crossover and mutation in order to combine the most successful characteristics of each model and produce fitter models. More sophisticated operators have been developed, but the standard GA usually provides a robust and efficient search. Although the choice of parameter settings such as crossover and mutation rate may depend largely on the type of problem being solved, numerous results show that certain parameter settings produce optimal performance for a wide range of problems and difficulties. In particular, a low (about half of the inverse of the population size) mutation rate is crucial for optimal results, but the choice of crossover method and rate do not seem to affect performance appreciably. Also, optimal efficiency is usually achieved with smaller (<50) populations. Lastly, tournament selection appears to be the best choice of selection methods due to its simplicity and its autoscaling properties. However, if a proportional selection method is used such as roulette wheel selection, fitness scaling is a necessity, and a high scaling factor (>2.0) should be used for the best performance. Three case studies are presented in which genetic algorithms are used to invert for crustal parameters. The first is an inversion for basement depth at Yucca mountain using gravity data, the second an inversion for velocity structure in the crust of the south island of New Zealand using receiver functions derived from teleseismic events, and the third is a similar receiver function inversion for crustal velocities beneath the Mendocino Triple Junction region of Northern California. The inversions demonstrate that genetic algorithms are effective in solving problems with reasonably large numbers of free parameters and with computationally expensive objective function calculations. More sophisticated techniques are presented for special problems. Niching and island model algorithms are introduced as methods to find multiple, distinct solutions to the nonunique problems that are typically seen in geophysics. Finally, hybrid algorithms are investigated as a way to improve the efficiency of the standard genetic algorithm.

  15. Using Genetic Algorithm and MODFLOW to Characterize Aquifer System of Northwest Florida

    EPA Science Inventory

    By integrating Genetic Algorithm and MODFLOW2005, an optimizing tool is developed to characterize the aquifer system of Region II, Northwest Florida. The history and the newest available observation data of the aquifer system is fitted automatically by using the numerical model c...

  16. Optimizing doped libraries by using genetic algorithms

    NASA Astrophysics Data System (ADS)

    Tomandl, Dirk; Schober, Andreas; Schwienhorst, Andreas

    1997-01-01

    The insertion of random sequences into protein-encoding genes in combination with biologicalselection techniques has become a valuable tool in the design of molecules that have usefuland possibly novel properties. By employing highly effective screening protocols, a functionaland unique structure that had not been anticipated can be distinguished among a hugecollection of inactive molecules that together represent all possible amino acid combinations.This technique is severely limited by its restriction to a library of manageable size. Oneapproach for limiting the size of a mutant library relies on `doping schemes', where subsetsof amino acids are generated that reveal only certain combinations of amino acids in a proteinsequence. Three mononucleotide mixtures for each codon concerned must be designed, suchthat the resulting codons that are assembled during chemical gene synthesis represent thedesired amino acid mixture on the level of the translated protein. In this paper we present adoping algorithm that `reverse translates' a desired mixture of certain amino acids into threemixtures of mononucleotides. The algorithm is designed to optimally bias these mixturestowards the codons of choice. This approach combines a genetic algorithm with localoptimization strategies based on the downhill simplex method. Disparate relativerepresentations of all amino acids (and stop codons) within a target set can be generated.Optional weighing factors are employed to emphasize the frequencies of certain amino acidsand their codon usage, and to compensate for reaction rates of different mononucleotidebuilding blocks (synthons) during chemical DNA synthesis. The effect of statistical errors thataccompany an experimental realization of calculated nucleotide mixtures on the generatedmixtures of amino acids is simulated. These simulations show that the robustness of differentoptima with respect to small deviations from calculated values depends on their concomitantfitness. Furthermore, the calculations probe the fitness landscape locally and allow apreliminary assessment of its structure.

  17. Longest jobs first algorithm in solving job shop scheduling using adaptive genetic algorithm (GA)

    NASA Astrophysics Data System (ADS)

    Alizadeh Sahzabi, Vahid; Karimi, Iman; Alizadeh Sahzabi, Navid; Mamaani Barnaghi, Peiman

    2012-01-01

    In this paper, genetic algorithm was used to solve job shop scheduling problems. One example discussed in JSSP (Job Shop Scheduling Problem) and I described how we can solve such these problems by genetic algorithm. The goal in JSSP is to gain the shortest process time. Furthermore I proposed a method to obtain best performance on performing all jobs in shortest time. The method mainly, is according to Genetic algorithm (GA) and crossing over between parents always follows the rule which the longest process is at the first in the job queue. In the other word chromosomes is suggested to sorts based on the longest processes to shortest i.e. "longest job first" says firstly look which machine contains most processing time during its performing all its jobs and that is the bottleneck. Secondly, start sort those jobs which are belonging to that specific machine descending. Based on the achieved results," longest jobs first" is the optimized status in job shop scheduling problems. In our results the accuracy would grow up to 94.7% for total processing time and the method improved 4% the accuracy of performing all jobs in the presented example.

  18. Efficient computation of the joint probability of multiple inherited risk alleles from pedigree data.

    PubMed

    Madsen, Thomas; Braun, Danielle; Peng, Gang; Parmigiani, Giovanni; Trippa, Lorenzo

    2018-06-25

    The Elston-Stewart peeling algorithm enables estimation of an individual's probability of harboring germline risk alleles based on pedigree data, and serves as the computational backbone of important genetic counseling tools. However, it remains limited to the analysis of risk alleles at a small number of genetic loci because its computing time grows exponentially with the number of loci considered. We propose a novel, approximate version of this algorithm, dubbed the peeling and paring algorithm, which scales polynomially in the number of loci. This allows extending peeling-based models to include many genetic loci. The algorithm creates a trade-off between accuracy and speed, and allows the user to control this trade-off. We provide exact bounds on the approximation error and evaluate it in realistic simulations. Results show that the loss of accuracy due to the approximation is negligible in important applications. This algorithm will improve genetic counseling tools by increasing the number of pathogenic risk alleles that can be addressed. To illustrate we create an extended five genes version of BRCAPRO, a widely used model for estimating the carrier probabilities of BRCA1 and BRCA2 risk alleles and assess its computational properties. © 2018 WILEY PERIODICALS, INC.

  19. Optimization of beam orientation in radiotherapy using planar geometry

    NASA Astrophysics Data System (ADS)

    Haas, O. C. L.; Burnham, K. J.; Mills, J. A.

    1998-08-01

    This paper proposes a new geometrical formulation of the coplanar beam orientation problem combined with a hybrid multiobjective genetic algorithm. The approach is demonstrated by optimizing the beam orientation in two dimensions, with the objectives being formulated using planar geometry. The traditional formulation of the objectives associated with the organs at risk has been modified to account for the use of complex dose delivery techniques such as beam intensity modulation. The new algorithm attempts to replicate the approach of a treatment planner whilst reducing the amount of computation required. Hybrid genetic search operators have been developed to improve the performance of the genetic algorithm by exploiting problem-specific features. The multiobjective genetic algorithm is formulated around the concept of Pareto optimality which enables the algorithm to search in parallel for different objectives. When the approach is applied without constraining the number of beams, the solution produces an indication of the minimum number of beams required. It is also possible to obtain non-dominated solutions for various numbers of beams, thereby giving the clinicians a choice in terms of the number of beams as well as in the orientation of these beams.

  20. Acoustic Impedance Inversion of Seismic Data Using Genetic Algorithm

    NASA Astrophysics Data System (ADS)

    Eladj, Said; Djarfour, Noureddine; Ferahtia, Djalal; Ouadfeul, Sid-Ali

    2013-04-01

    The inversion of seismic data can be used to constrain estimates of the Earth's acoustic impedance structure. This kind of problem is usually known to be non-linear, high-dimensional, with a complex search space which may be riddled with many local minima, and results in irregular objective functions. We investigate here the performance and the application of a genetic algorithm, in the inversion of seismic data. The proposed algorithm has the advantage of being easily implemented without getting stuck in local minima. The effects of population size, Elitism strategy, uniform cross-over and lower mutation are examined. The optimum solution parameters and performance were decided as a function of the testing error convergence with respect to the generation number. To calculate the fitness function, we used L2 norm of the sample-to-sample difference between the reference and the inverted trace. The cross-over probability is of 0.9-0.95 and mutation has been tested at 0.01 probability. The application of such a genetic algorithm to synthetic data shows that the inverted acoustic impedance section was efficient. Keywords: Seismic, Inversion, acoustic impedance, genetic algorithm, fitness functions, cross-over, mutation.

  1. A Comparison Study of Machine Learning Based Algorithms for Fatigue Crack Growth Calculation.

    PubMed

    Wang, Hongxun; Zhang, Weifang; Sun, Fuqiang; Zhang, Wei

    2017-05-18

    The relationships between the fatigue crack growth rate ( d a / d N ) and stress intensity factor range ( Δ K ) are not always linear even in the Paris region. The stress ratio effects on fatigue crack growth rate are diverse in different materials. However, most existing fatigue crack growth models cannot handle these nonlinearities appropriately. The machine learning method provides a flexible approach to the modeling of fatigue crack growth because of its excellent nonlinear approximation and multivariable learning ability. In this paper, a fatigue crack growth calculation method is proposed based on three different machine learning algorithms (MLAs): extreme learning machine (ELM), radial basis function network (RBFN) and genetic algorithms optimized back propagation network (GABP). The MLA based method is validated using testing data of different materials. The three MLAs are compared with each other as well as the classical two-parameter model ( K * approach). The results show that the predictions of MLAs are superior to those of K * approach in accuracy and effectiveness, and the ELM based algorithms show overall the best agreement with the experimental data out of the three MLAs, for its global optimization and extrapolation ability.

  2. Structures, phase stabilities, and electrical potentials of Li-Si battery anode materials

    NASA Astrophysics Data System (ADS)

    Tipton, William W.; Bealing, Clive R.; Mathew, Kiran; Hennig, Richard G.

    2013-05-01

    The Li-Si materials system holds promise for use as an anode in Li-ion battery applications. For this system, we determine the charge capacity, voltage profiles, and energy storage density solely by ab initio methods without any experimental input. We determine the energetics of the stable and metastable Li-Si phases likely to form during the charging and discharging of a battery. Ab initio molecular dynamics simulations are used to model the structure of amorphous Li-Si as a function of composition, and a genetic algorithm coupled to density-functional theory searches the Li-Si binary phase diagram for small-cell, metastable crystal structures. Calculations of the phonon densities of states using density-functional perturbation theory for selected structures determine the importance of vibrational, including zero-point, contributions to the free energies. The energetics and local structural motifs of these metastable Li-Si phases closely resemble those of the amorphous phases, making these small unit cell crystal phases good approximants of the amorphous phase for use in further studies. The charge capacity is estimated, and the electrical potential profiles and the energy density of Li-Si anodes are predicted. We find, in good agreement with experimental measurements, that the formation of amorphous Li-Si only slightly increases the anode potential. Additionally, the genetic algorithm identifies a previously unreported member of the Li-Si binary phase diagram with composition Li5Si2 which is stable at 0 K with respect to previously known phases. We discuss its relationship to the partially occupied Li7Si3 phase.

  3. Ethanol mediated As(III) adsorption onto Zn-loaded pinecone biochar: Experimental investigation, modeling, and optimization using hybrid artificial neural network-genetic algorithm approach.

    PubMed

    Zafar, Mohd; Van Vinh, N; Behera, Shishir Kumar; Park, Hung-Suck

    2017-04-01

    Organic matters (OMs) and their oxidization products often influence the fate and transport of heavy metals in the subsurface aqueous systems through interaction with the mineral surfaces. This study investigates the ethanol (EtOH)-mediated As(III) adsorption onto Zn-loaded pinecone (PC) biochar through batch experiments conducted under Box-Behnken design. The effect of EtOH on As(III) adsorption mechanism was quantitatively elucidated by fitting the experimental data using artificial neural network and quadratic modeling approaches. The quadratic model could describe the limiting nature of EtOH and pH on As(III) adsorption, whereas neural network revealed the stronger influence of EtOH (64.5%) followed by pH (20.75%) and As(III) concentration (14.75%) on the adsorption phenomena. Besides, the interaction among process variables indicated that EtOH enhances As(III) adsorption over a pH range of 2 to 7, possibly due to facilitation of ligand-metal(Zn) binding complexation mechanism. Eventually, hybrid response surface model-genetic algorithm (RSM-GA) approach predicted a better optimal solution than RSM, i.e., the adsorptive removal of As(III) (10.47μg/g) is facilitated at 30.22mg C/L of EtOH with initial As(III) concentration of 196.77μg/L at pH5.8. The implication of this investigation might help in understanding the application of biochar for removal of various As(III) species in the presence of OM. Copyright © 2016. Published by Elsevier B.V.

  4. Reconstruction and Validation of a Genome-Scale Metabolic Model for the Filamentous Fungus Neurospora crassa Using FARM

    PubMed Central

    Hood, Heather M.; Ocasio, Linda R.; Sachs, Matthew S.; Galagan, James E.

    2013-01-01

    The filamentous fungus Neurospora crassa played a central role in the development of twentieth-century genetics, biochemistry and molecular biology, and continues to serve as a model organism for eukaryotic biology. Here, we have reconstructed a genome-scale model of its metabolism. This model consists of 836 metabolic genes, 257 pathways, 6 cellular compartments, and is supported by extensive manual curation of 491 literature citations. To aid our reconstruction, we developed three optimization-based algorithms, which together comprise Fast Automated Reconstruction of Metabolism (FARM). These algorithms are: LInear MEtabolite Dilution Flux Balance Analysis (limed-FBA), which predicts flux while linearly accounting for metabolite dilution; One-step functional Pruning (OnePrune), which removes blocked reactions with a single compact linear program; and Consistent Reproduction Of growth/no-growth Phenotype (CROP), which reconciles differences between in silico and experimental gene essentiality faster than previous approaches. Against an independent test set of more than 300 essential/non-essential genes that were not used to train the model, the model displays 93% sensitivity and specificity. We also used the model to simulate the biochemical genetics experiments originally performed on Neurospora by comprehensively predicting nutrient rescue of essential genes and synthetic lethal interactions, and we provide detailed pathway-based mechanistic explanations of our predictions. Our model provides a reliable computational framework for the integration and interpretation of ongoing experimental efforts in Neurospora, and we anticipate that our methods will substantially reduce the manual effort required to develop high-quality genome-scale metabolic models for other organisms. PMID:23935467

  5. Hybrid algorithms for fuzzy reverse supply chain network design.

    PubMed

    Che, Z H; Chiang, Tzu-An; Kuo, Y C; Cui, Zhihua

    2014-01-01

    In consideration of capacity constraints, fuzzy defect ratio, and fuzzy transport loss ratio, this paper attempted to establish an optimized decision model for production planning and distribution of a multiphase, multiproduct reverse supply chain, which addresses defects returned to original manufacturers, and in addition, develops hybrid algorithms such as Particle Swarm Optimization-Genetic Algorithm (PSO-GA), Genetic Algorithm-Simulated Annealing (GA-SA), and Particle Swarm Optimization-Simulated Annealing (PSO-SA) for solving the optimized model. During a case study of a multi-phase, multi-product reverse supply chain network, this paper explained the suitability of the optimized decision model and the applicability of the algorithms. Finally, the hybrid algorithms showed excellent solving capability when compared with original GA and PSO methods.

  6. Hybrid Algorithms for Fuzzy Reverse Supply Chain Network Design

    PubMed Central

    Che, Z. H.; Chiang, Tzu-An; Kuo, Y. C.

    2014-01-01

    In consideration of capacity constraints, fuzzy defect ratio, and fuzzy transport loss ratio, this paper attempted to establish an optimized decision model for production planning and distribution of a multiphase, multiproduct reverse supply chain, which addresses defects returned to original manufacturers, and in addition, develops hybrid algorithms such as Particle Swarm Optimization-Genetic Algorithm (PSO-GA), Genetic Algorithm-Simulated Annealing (GA-SA), and Particle Swarm Optimization-Simulated Annealing (PSO-SA) for solving the optimized model. During a case study of a multi-phase, multi-product reverse supply chain network, this paper explained the suitability of the optimized decision model and the applicability of the algorithms. Finally, the hybrid algorithms showed excellent solving capability when compared with original GA and PSO methods. PMID:24892057

  7. Comparison of Genetic Algorithm and Hill Climbing for Shortest Path Optimization Mapping

    NASA Astrophysics Data System (ADS)

    Fronita, Mona; Gernowo, Rahmat; Gunawan, Vincencius

    2018-02-01

    Traveling Salesman Problem (TSP) is an optimization to find the shortest path to reach several destinations in one trip without passing through the same city and back again to the early departure city, the process is applied to the delivery systems. This comparison is done using two methods, namely optimization genetic algorithm and hill climbing. Hill Climbing works by directly selecting a new path that is exchanged with the neighbour's to get the track distance smaller than the previous track, without testing. Genetic algorithms depend on the input parameters, they are the number of population, the probability of crossover, mutation probability and the number of generations. To simplify the process of determining the shortest path supported by the development of software that uses the google map API. Tests carried out as much as 20 times with the number of city 8, 16, 24 and 32 to see which method is optimal in terms of distance and time computation. Based on experiments conducted with a number of cities 3, 4, 5 and 6 producing the same value and optimal distance for the genetic algorithm and hill climbing, the value of this distance begins to differ with the number of city 7. The overall results shows that these tests, hill climbing are more optimal to number of small cities and the number of cities over 30 optimized using genetic algorithms.

  8. Weather prediction using a genetic memory

    NASA Technical Reports Server (NTRS)

    Rogers, David

    1990-01-01

    Kanaerva's sparse distributed memory (SDM) is an associative memory model based on the mathematical properties of high dimensional binary address spaces. Holland's genetic algorithms are a search technique for high dimensional spaces inspired by evolutional processes of DNA. Genetic Memory is a hybrid of the above two systems, in which the memory uses a genetic algorithm to dynamically reconfigure its physical storage locations to reflect correlations between the stored addresses and data. This architecture is designed to maximize the ability of the system to scale-up to handle real world problems.

  9. iNJclust: Iterative Neighbor-Joining Tree Clustering Framework for Inferring Population Structure.

    PubMed

    Limpiti, Tulaya; Amornbunchornvej, Chainarong; Intarapanich, Apichart; Assawamakin, Anunchai; Tongsima, Sissades

    2014-01-01

    Understanding genetic differences among populations is one of the most important issues in population genetics. Genetic variations, e.g., single nucleotide polymorphisms, are used to characterize commonality and difference of individuals from various populations. This paper presents an efficient graph-based clustering framework which operates iteratively on the Neighbor-Joining (NJ) tree called the iNJclust algorithm. The framework uses well-known genetic measurements, namely the allele-sharing distance, the neighbor-joining tree, and the fixation index. The behavior of the fixation index is utilized in the algorithm's stopping criterion. The algorithm provides an estimated number of populations, individual assignments, and relationships between populations as outputs. The clustering result is reported in the form of a binary tree, whose terminal nodes represent the final inferred populations and the tree structure preserves the genetic relationships among them. The clustering performance and the robustness of the proposed algorithm are tested extensively using simulated and real data sets from bovine, sheep, and human populations. The result indicates that the number of populations within each data set is reasonably estimated, the individual assignment is robust, and the structure of the inferred population tree corresponds to the intrinsic relationships among populations within the data.

  10. Computational intelligence-based optimization of maximally stable extremal region segmentation for object detection

    NASA Astrophysics Data System (ADS)

    Davis, Jeremy E.; Bednar, Amy E.; Goodin, Christopher T.; Durst, Phillip J.; Anderson, Derek T.; Bethel, Cindy L.

    2017-05-01

    Particle swarm optimization (PSO) and genetic algorithms (GAs) are two optimization techniques from the field of computational intelligence (CI) for search problems where a direct solution can not easily be obtained. One such problem is finding an optimal set of parameters for the maximally stable extremal region (MSER) algorithm to detect areas of interest in imagery. Specifically, this paper describes the design of a GA and PSO for optimizing MSER parameters to detect stop signs in imagery produced via simulation for use in an autonomous vehicle navigation system. Several additions to the GA and PSO are required to successfully detect stop signs in simulated images. These additions are a primary focus of this paper and include: the identification of an appropriate fitness function, the creation of a variable mutation operator for the GA, an anytime algorithm modification to allow the GA to compute a solution quickly, the addition of an exponential velocity decay function to the PSO, the addition of an "execution best" omnipresent particle to the PSO, and the addition of an attractive force component to the PSO velocity update equation. Experimentation was performed with the GA using various combinations of selection, crossover, and mutation operators and experimentation was also performed with the PSO using various combinations of neighborhood topologies, swarm sizes, cognitive influence scalars, and social influence scalars. The results of both the GA and PSO optimized parameter sets are presented. This paper details the benefits and drawbacks of each algorithm in terms of detection accuracy, execution speed, and additions required to generate successful problem specific parameter sets.

  11. Improved adaptive genetic algorithm with sparsity constraint applied to thermal neutron CT reconstruction of two-phase flow

    NASA Astrophysics Data System (ADS)

    Yan, Mingfei; Hu, Huasi; Otake, Yoshie; Taketani, Atsushi; Wakabayashi, Yasuo; Yanagimachi, Shinzo; Wang, Sheng; Pan, Ziheng; Hu, Guang

    2018-05-01

    Thermal neutron computer tomography (CT) is a useful tool for visualizing two-phase flow due to its high imaging contrast and strong penetrability of neutrons for tube walls constructed with metallic material. A novel approach for two-phase flow CT reconstruction based on an improved adaptive genetic algorithm with sparsity constraint (IAGA-SC) is proposed in this paper. In the algorithm, the neighborhood mutation operator is used to ensure the continuity of the reconstructed object. The adaptive crossover probability P c and mutation probability P m are improved to help the adaptive genetic algorithm (AGA) achieve the global optimum. The reconstructed results for projection data, obtained from Monte Carlo simulation, indicate that the comprehensive performance of the IAGA-SC algorithm exceeds the adaptive steepest descent-projection onto convex sets (ASD-POCS) algorithm in restoring typical and complex flow regimes. It especially shows great advantages in restoring the simply connected flow regimes and the shape of object. In addition, the CT experiment for two-phase flow phantoms was conducted on the accelerator-driven neutron source to verify the performance of the developed IAGA-SC algorithm.

  12. Creating IRT-Based Parallel Test Forms Using the Genetic Algorithm Method

    ERIC Educational Resources Information Center

    Sun, Koun-Tem; Chen, Yu-Jen; Tsai, Shu-Yen; Cheng, Chien-Fen

    2008-01-01

    In educational measurement, the construction of parallel test forms is often a combinatorial optimization problem that involves the time-consuming selection of items to construct tests having approximately the same test information functions (TIFs) and constraints. This article proposes a novel method, genetic algorithm (GA), to construct parallel…

  13. Genetic Algorithm Phase Retrieval for the Systematic Image-Based Optical Alignment Testbed

    NASA Technical Reports Server (NTRS)

    Rakoczy, John; Steincamp, James; Taylor, Jaime

    2003-01-01

    A reduced surrogate, one point crossover genetic algorithm with random rank-based selection was used successfully to estimate the multiple phases of a segmented optical system modeled on the seven-mirror Systematic Image-Based Optical Alignment testbed located at NASA's Marshall Space Flight Center.

  14. Using Genetic Algorithm and MODFLOW to Characterize Aquifer System of Northwest Florida (Published Proceedings)

    EPA Science Inventory

    By integrating Genetic Algorithm and MODFLOW2005, an optimizing tool is developed to characterize the aquifer system of Region II, Northwest Florida. The history and the newest available observation data of the aquifer system is fitted automatically by using the numerical model c...

  15. Genetic algorithm to solve the problems of lectures and practicums scheduling

    NASA Astrophysics Data System (ADS)

    Syahputra, M. F.; Apriani, R.; Sawaluddin; Abdullah, D.; Albra, W.; Heikal, M.; Abdurrahman, A.; Khaddafi, M.

    2018-02-01

    Generally, the scheduling process is done manually. However, this method has a low accuracy level, along with possibilities that a scheduled process collides with another scheduled process. When doing theory class and practicum timetable scheduling process, there are numerous problems, such as lecturer teaching schedule collision, schedule collision with another schedule, practicum lesson schedules that collides with theory class, and the number of classrooms available. In this research, genetic algorithm is implemented to perform theory class and practicum timetable scheduling process. The algorithm will be used to process the data containing lists of lecturers, courses, and class rooms, obtained from information technology department at University of Sumatera Utara. The result of scheduling process using genetic algorithm is the most optimal timetable that conforms to available time slots, class rooms, courses, and lecturer schedules.

  16. Multiple feature fusion via covariance matrix for visual tracking

    NASA Astrophysics Data System (ADS)

    Jin, Zefenfen; Hou, Zhiqiang; Yu, Wangsheng; Wang, Xin; Sun, Hui

    2018-04-01

    Aiming at the problem of complicated dynamic scenes in visual target tracking, a multi-feature fusion tracking algorithm based on covariance matrix is proposed to improve the robustness of the tracking algorithm. In the frame-work of quantum genetic algorithm, this paper uses the region covariance descriptor to fuse the color, edge and texture features. It also uses a fast covariance intersection algorithm to update the model. The low dimension of region covariance descriptor, the fast convergence speed and strong global optimization ability of quantum genetic algorithm, and the fast computation of fast covariance intersection algorithm are used to improve the computational efficiency of fusion, matching, and updating process, so that the algorithm achieves a fast and effective multi-feature fusion tracking. The experiments prove that the proposed algorithm can not only achieve fast and robust tracking but also effectively handle interference of occlusion, rotation, deformation, motion blur and so on.

  17. GAtor: A First-Principles Genetic Algorithm for Molecular Crystal Structure Prediction.

    PubMed

    Curtis, Farren; Li, Xiayue; Rose, Timothy; Vázquez-Mayagoitia, Álvaro; Bhattacharya, Saswata; Ghiringhelli, Luca M; Marom, Noa

    2018-04-10

    We present the implementation of GAtor, a massively parallel, first-principles genetic algorithm (GA) for molecular crystal structure prediction. GAtor is written in Python and currently interfaces with the FHI-aims code to perform local optimizations and energy evaluations using dispersion-inclusive density functional theory (DFT). GAtor offers a variety of fitness evaluation, selection, crossover, and mutation schemes. Breeding operators designed specifically for molecular crystals provide a balance between exploration and exploitation. Evolutionary niching is implemented in GAtor by using machine learning to cluster the dynamically updated population by structural similarity and then employing a cluster-based fitness function. Evolutionary niching promotes uniform sampling of the potential energy surface by evolving several subpopulations, which helps overcome initial pool biases and selection biases (genetic drift). The various settings offered by GAtor increase the likelihood of locating numerous low-energy minima, including those located in disconnected, hard to reach regions of the potential energy landscape. The best structures generated are re-relaxed and re-ranked using a hierarchy of increasingly accurate DFT functionals and dispersion methods. GAtor is applied to a chemically diverse set of four past blind test targets, characterized by different types of intermolecular interactions. The experimentally observed structures and other low-energy structures are found for all four targets. In particular, for Target II, 5-cyano-3-hydroxythiophene, the top ranked putative crystal structure is a Z' = 2 structure with P1̅ symmetry and a scaffold packing motif, which has not been reported previously.

  18. Automatic Registration of TLS-TLS and TLS-MLS Point Clouds Using a Genetic Algorithm

    PubMed Central

    Yan, Li; Xie, Hong; Chen, Changjun

    2017-01-01

    Registration of point clouds is a fundamental issue in Light Detection and Ranging (LiDAR) remote sensing because point clouds scanned from multiple scan stations or by different platforms need to be transformed to a uniform coordinate reference frame. This paper proposes an efficient registration method based on genetic algorithm (GA) for automatic alignment of two terrestrial LiDAR scanning (TLS) point clouds (TLS-TLS point clouds) and alignment between TLS and mobile LiDAR scanning (MLS) point clouds (TLS-MLS point clouds). The scanning station position acquired by the TLS built-in GPS and the quasi-horizontal orientation of the LiDAR sensor in data acquisition are used as constraints to narrow the search space in GA. A new fitness function to evaluate the solutions for GA, named as Normalized Sum of Matching Scores, is proposed for accurate registration. Our method is divided into five steps: selection of matching points, initialization of population, transformation of matching points, calculation of fitness values, and genetic operation. The method is verified using a TLS-TLS data set and a TLS-MLS data set. The experimental results indicate that the RMSE of registration of TLS-TLS point clouds is 3~5 mm, and that of TLS-MLS point clouds is 2~4 cm. The registration integrating the existing well-known ICP with GA is further proposed to accelerate the optimization and its optimizing time decreases by about 50%. PMID:28850100

  19. Automatic Registration of TLS-TLS and TLS-MLS Point Clouds Using a Genetic Algorithm.

    PubMed

    Yan, Li; Tan, Junxiang; Liu, Hua; Xie, Hong; Chen, Changjun

    2017-08-29

    Registration of point clouds is a fundamental issue in Light Detection and Ranging (LiDAR) remote sensing because point clouds scanned from multiple scan stations or by different platforms need to be transformed to a uniform coordinate reference frame. This paper proposes an efficient registration method based on genetic algorithm (GA) for automatic alignment of two terrestrial LiDAR scanning (TLS) point clouds (TLS-TLS point clouds) and alignment between TLS and mobile LiDAR scanning (MLS) point clouds (TLS-MLS point clouds). The scanning station position acquired by the TLS built-in GPS and the quasi-horizontal orientation of the LiDAR sensor in data acquisition are used as constraints to narrow the search space in GA. A new fitness function to evaluate the solutions for GA, named as Normalized Sum of Matching Scores, is proposed for accurate registration. Our method is divided into five steps: selection of matching points, initialization of population, transformation of matching points, calculation of fitness values, and genetic operation. The method is verified using a TLS-TLS data set and a TLS-MLS data set. The experimental results indicate that the RMSE of registration of TLS-TLS point clouds is 3~5 mm, and that of TLS-MLS point clouds is 2~4 cm. The registration integrating the existing well-known ICP with GA is further proposed to accelerate the optimization and its optimizing time decreases by about 50%.

  20. Radar Array Processing of Experimental Data Via the Scan-MUSIC Algorithm

    DTIC Science & Technology

    2004-06-01

    Radar Array Processing of Experimental Data Via the Scan- MUSIC Algorithm by Canh Ly ARL-TR-3135 June 2004...Processing of Experimental Data Via the Scan- MUSIC Algorithm Canh Ly Sensors and Electron Devices Directorate, ARL...NUMBER 5b. GRANT NUMBER 4. TITLE AND SUBTITLE Radar Array Processing of Experimental Data Via the Scan- MUSIC Algorithm 5c. PROGRAM ELEMENT NUMBER 5d

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