Sample records for gi ieee computer

  1. Introspections on the Semantic Gap

    DTIC Science & Technology

    2015-04-14

    cloud comput - ing. Zhang received an MS in computer science from Stony Brook University. Contact him at dozhang@ cs.stonybrook.edu. Donald E. Porter...designated by other documentation. ... 2 March/April 2015 Copublished by the IEEE Computer and Reliability Societies 1540-7993/15/$31.00 © 2015 IEEE IEEE S...pauses the VM, and the VMI tool introspects the process descriptor list. In contrast, an asynchronous mechanism would intro - spect memory

  2. RF Fiber Optic Link.

    DTIC Science & Technology

    1984-06-01

    index fiber has approximately 400 MHz/km. In the near future improvements in the material dispersion of glass may allow single mode bandwidths well above...attractive for K-band *(12 GI~z) TYRO, high definition TV channels, as well as the SBS (Satellite Business Systems) operation, in the near future.1...34Noise and Distortion Characteristics of Semi-Conductor Lasers in Optical Fiber Communication Systems", IEEE J. Quantum Electron., vol. QE-18, pp. 543-555

  3. 48 CFR 52.223-16 - IEEE 1680 Standard for the Environmental Assessment of Personal Computer Products.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Environmental Assessment of Personal Computer Products. 52.223-16 Section 52.223-16 Federal Acquisition... Assessment of Personal Computer Products. As prescribed in 23.705(b)(1), insert the following clause: IEEE 1680 Standard for the Environmental Assessment of Personal Computer Products (DEC 2007) (a) Definitions...

  4. 48 CFR 52.223-16 - IEEE 1680 Standard for the Environmental Assessment of Personal Computer Products.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Environmental Assessment of Personal Computer Products. 52.223-16 Section 52.223-16 Federal Acquisition... Assessment of Personal Computer Products. As prescribed in 23.705(b)(1), insert the following clause: IEEE 1680 Standard for the Environmental Assessment of Personal Computer Products (DEC 2007) (a) Definitions...

  5. 48 CFR 52.223-16 - IEEE 1680 Standard for the Environmental Assessment of Personal Computer Products.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Environmental Assessment of Personal Computer Products. 52.223-16 Section 52.223-16 Federal Acquisition... Assessment of Personal Computer Products. As prescribed in 23.705(b)(1), insert the following clause: IEEE 1680 Standard for the Environmental Assessment of Personal Computer Products (DEC 2007) (a) Definitions...

  6. 48 CFR 52.223-16 - IEEE 1680 Standard for the Environmental Assessment of Personal Computer Products.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Environmental Assessment of Personal Computer Products. 52.223-16 Section 52.223-16 Federal Acquisition... Assessment of Personal Computer Products. As prescribed in 23.706(b)(1), insert the following clause: IEEE 1680 Standard for the Environmental Assessment of Personal Computer Products (DEC 2007) (a) Definitions...

  7. gProcess and ESIP Platforms for Satellite Imagery Processing over the Grid

    NASA Astrophysics Data System (ADS)

    Bacu, Victor; Gorgan, Dorian; Rodila, Denisa; Pop, Florin; Neagu, Gabriel; Petcu, Dana

    2010-05-01

    The Environment oriented Satellite Data Processing Platform (ESIP) is developed through the SEE-GRID-SCI (SEE-GRID eInfrastructure for regional eScience) co-funded by the European Commission through FP7 [1]. The gProcess Platform [2] is a set of tools and services supporting the development and the execution over the Grid of the workflow based processing, and particularly the satelite imagery processing. The ESIP [3], [4] is build on top of the gProcess platform by adding a set of satellite image processing software modules and meteorological algorithms. The satellite images can reveal and supply important information on earth surface parameters, climate data, pollution level, weather conditions that can be used in different research areas. Generally, the processing algorithms of the satellite images can be decomposed in a set of modules that forms a graph representation of the processing workflow. Two types of workflows can be defined in the gProcess platform: abstract workflow (PDG - Process Description Graph), in which the user defines conceptually the algorithm, and instantiated workflow (iPDG - instantiated PDG), which is the mapping of the PDG pattern on particular satellite image and meteorological data [5]. The gProcess platform allows the definition of complex workflows by combining data resources, operators, services and sub-graphs. The gProcess platform is developed for the gLite middleware that is available in EGEE and SEE-GRID infrastructures [6]. gProcess exposes the specific functionality through web services [7]. The Editor Web Service retrieves information on available resources that are used to develop complex workflows (available operators, sub-graphs, services, supported resources, etc.). The Manager Web Service deals with resources management (uploading new resources such as workflows, operators, services, data, etc.) and in addition retrieves information on workflows. The Executor Web Service manages the execution of the instantiated workflows on the Grid infrastructure. In addition, this web service monitors the execution and generates statistical data that are important to evaluate performances and to optimize execution. The Viewer Web Service allows access to input and output data. To prove and to validate the utility of the gProcess and ESIP platforms there were developed the GreenView and GreenLand applications. The GreenView related functionality includes the refinement of some meteorological data such as temperature, and the calibration of the satellite images based on field measurements. The GreenLand application performs the classification of the satellite images by using a set of vegetation indices. The gProcess and ESIP platforms are used as well in GiSHEO project [8] to support the processing of Earth Observation data over the Grid in eGLE (GiSHEO eLearning Environment). Experiments of performance assessment were conducted and they have revealed that the workflow-based execution could improve the execution time of a satellite image processing algorithm [9]. It is not a reliable solution to execute all the workflow nodes on different machines. The execution of some nodes can be more time consuming and they will be performed in a longer time than other nodes. The total execution time will be affected because some nodes will slow down the execution. It is important to correctly balance the workflow nodes. Based on some optimization strategy the workflow nodes can be grouped horizontally, vertically or in a hybrid approach. In this way, those operators will be executed on one machine and also the data transfer between workflow nodes will be lower. The dynamic nature of the Grid infrastructure makes it more exposed to the occurrence of failures. These failures can occur at worker node, services availability, storage element, etc. Currently gProcess has support for some basic error prevention and error management solutions. In future, some more advanced error prevention and management solutions will be integrated in the gProcess platform. References [1] SEE-GRID-SCI Project, http://www.see-grid-sci.eu/ [2] Bacu V., Stefanut T., Rodila D., Gorgan D., Process Description Graph Composition by gProcess Platform. HiPerGRID - 3rd International Workshop on High Performance Grid Middleware, 28 May, Bucharest. Proceedings of CSCS-17 Conference, Vol.2., ISSN 2066-4451, pp. 423-430, (2009). [3] ESIP Platform, http://wiki.egee-see.org/index.php/JRA1_Commonalities [4] Gorgan D., Bacu V., Rodila D., Pop Fl., Petcu D., Experiments on ESIP - Environment oriented Satellite Data Processing Platform. SEE-GRID-SCI User Forum, 9-10 Dec 2009, Bogazici University, Istanbul, Turkey, ISBN: 978-975-403-510-0, pp. 157-166 (2009). [5] Radu, A., Bacu, V., Gorgan, D., Diagrammatic Description of Satellite Image Processing Workflow. Workshop on Grid Computing Applications Development (GridCAD) at the SYNASC Symposium, 28 September 2007, Timisoara, IEEE Computer Press, ISBN 0-7695-3078-8, 2007, pp. 341-348 (2007). [6] Gorgan D., Bacu V., Stefanut T., Rodila D., Mihon D., Grid based Satellite Image Processing Platform for Earth Observation Applications Development. IDAACS'2009 - IEEE Fifth International Workshop on "Intelligent Data Acquisition and Advanced Computing Systems: Technology and Applications", 21-23 September, Cosenza, Italy, IEEE Published in Computer Press, 247-252 (2009). [7] Rodila D., Bacu V., Gorgan D., Integration of Satellite Image Operators as Workflows in the gProcess Application. Proceedings of ICCP2009 - IEEE 5th International Conference on Intelligent Computer Communication and Processing, 27-29 Aug, 2009 Cluj-Napoca. ISBN: 978-1-4244-5007-7, pp. 355-358 (2009). [8] GiSHEO consortium, Project site, http://gisheo.info.uvt.ro [9] Bacu V., Gorgan D., Graph Based Evaluation of Satellite Imagery Processing over Grid. ISPDC 2008 - 7th International Symposium on Parallel and Distributed Computing, July 1-5, 2008, Krakow, Poland. IEEE Computer Society 2008, ISBN: 978-0-7695-3472-5, pp. 147-154.

  8. 77 FR 50726 - Software Requirement Specifications for Digital Computer Software and Complex Electronics Used in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... Computer Software and Complex Electronics Used in Safety Systems of Nuclear Power Plants AGENCY: Nuclear...-1209, ``Software Requirement Specifications for Digital Computer Software and Complex Electronics used... Electronics Engineers (ANSI/IEEE) Standard 830-1998, ``IEEE Recommended Practice for Software Requirements...

  9. GPUs: An Emerging Platform for General-Purpose Computation

    DTIC Science & Technology

    2007-08-01

    programming; real-time cinematic quality graphics Peak stream (26) License required (limited time no- cost evaluation program) Commercially...folding.stanford.edu (accessed 30 March 2007). 2. Fan, Z.; Qiu, F.; Kaufman, A.; Yoakum-Stover, S. GPU Cluster for High Performance Computing. ACM/IEEE...accessed 30 March 2007). 8. Goodnight, N.; Wang, R.; Humphreys, G. Computation on Programmable Graphics Hardware. IEEE Computer Graphics and

  10. Computer Simulation of the Virulome of Bacillus anthracis Using Proteomics

    DTIC Science & Technology

    2006-07-31

    hypothetical protein gi|47526566 spermidine /putrescine ABC transporter, spermidine /putrescine-binding protein gi|47526625 oligoendopeptidase F, putative gi...glutamyl-trna(gln) amidotransferase, a subunit x gi|50196927 aspartate aminotransferase x gi|50196970 spermidine synthase x

  11. 78 FR 47014 - Configuration Management Plans for Digital Computer Software Used in Safety Systems of Nuclear...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-02

    ... Software Used in Safety Systems of Nuclear Power Plants AGENCY: Nuclear Regulatory Commission. ACTION... Computer Software Used in Safety Systems of Nuclear Power Plants.'' This RG endorses, with clarifications... Electrical and Electronic Engineers (IEEE) Standard 828-2005, ``IEEE Standard for Software Configuration...

  12. The Sound of Freedom. Naval Weapons Technology at Dahlgren, Virginia, 1918-2006

    DTIC Science & Technology

    2006-01-01

    the TRINITY device, before later succeeding J. Robert Oppenheimer as the director of Los Alamos National Laboratory. Other former Dahlgren...and the Computer (Cambridge, Mass.: The MIT Press, 1999); Michael R. Williams, A History of Computing Technology, 2nd ed. ( Los Alamos , Calif.: IEEE...Minutes of Advisory Council. 3. Ibid. 4. Ibid.; Michael R. Williams, A History of Computing Technology, 2nd ed. ( Los Alamos , Calif.: IEEE Computer

  13. Reliability Evaluation of Computer Systems.

    DTIC Science & Technology

    1981-01-01

    algorithms in hardware is not restricted by the designs of particular circuits. Applications could be made in new computer architectures; one candidate...pp. 137-148, IEEE, Chicago, Illinois, September 1963. (With J.F. Wakerly ) "Design of Low-Cost General-Purpose Self- Diagnosing Computers," Proc...34 Proc., IEEE Int’l Solid-State Circuits Conference, Philadelphia, Pennsylvania, February 16-18, 1977. (With J.F. Wakerly ) "Microcomputers in the

  14. IEEE International Symposium on Biomedical Imaging.

    PubMed

    2017-01-01

    The IEEE International Symposium on Biomedical Imaging (ISBI) is a scientific conference dedicated to mathematical, algorithmic, and computational aspects of biological and biomedical imaging, across all scales of observation. It fosters knowledge transfer among different imaging communities and contributes to an integrative approach to biomedical imaging. ISBI is a joint initiative from the IEEE Signal Processing Society (SPS) and the IEEE Engineering in Medicine and Biology Society (EMBS). The 2018 meeting will include tutorials, and a scientific program composed of plenary talks, invited special sessions, challenges, as well as oral and poster presentations of peer-reviewed papers. High-quality papers are requested containing original contributions to the topics of interest including image formation and reconstruction, computational and statistical image processing and analysis, dynamic imaging, visualization, image quality assessment, and physical, biological, and statistical modeling. Accepted 4-page regular papers will be published in the symposium proceedings published by IEEE and included in IEEE Xplore. To encourage attendance by a broader audience of imaging scientists and offer additional presentation opportunities, ISBI 2018 will continue to have a second track featuring posters selected from 1-page abstract submissions without subsequent archival publication.

  15. An Efficient Power Saving Mechanism for Delay-Guaranteed Services in IEEE 802.16e

    NASA Astrophysics Data System (ADS)

    Park, Yunju; Hwang, Gang Uk

    As the IEEE 802.16e Wireless Metropolitan Access Network (WMAN) supports the mobility of a mobile station (MS), increasing MS power efficiency has become an important issue. In this paper, we analyze the sleep-mode operation for an efficient power saving mechanism for delay-guaranteed services in the IEEE 802.16e WMAN and observe the effects of the operating parameters related to this operation. For the analysis we use the M/GI/1/K queueing system with multiple vacations, exhaustive services and setup times. In the analysis, we consider the power consumption during the wake-mode period as well as the sleep-mode period. As a performance measure for the power consumption, we propose the power consumption per unit time per effective arrival which considers the power consumption and the packet blocking probability simultaneously. In addition, since we consider delay-guaranteed services, the average packet response delay is also considered as a performance measure. Based on the performance measures, we obtain the optimal sleep-mode operation which minimizes the power consumption per unit time per effective arrival with a given delay requirement. Numerical studies are also provided to investigate the system performance and to show how to achieve our objective.

  16. DESPIC: Detecting Early Signatures of Persuasion in Information Cascades

    DTIC Science & Technology

    2015-08-27

    over NoSQL Databases, Proceedings of the 14th IEEE/ACM International Symposium on Cluster, Cloud and Grid Computing (CCGrid 2014). 26-MAY-14, . : , P...over NoSQL Databases. Proceedings of the 14th IEEE/ACM International Symposium on Cluster, Cloud and Grid Computing (CCGrid 2014). Chicago, IL, USA...distributed NoSQL databases including HBase and Riak, we finalized the requirements of the optimal computational architecture to support our framework

  17. Software And Systems Engineering Risk Management

    DTIC Science & Technology

    2010-04-01

    RSKM 2004 COSO Enterprise RSKM Framework 2006 ISO/IEC 16085 Risk Management Process 2008 ISO/IEC 12207 Software Lifecycle Processes 2009 ISO/IEC...1 Software And Systems Engineering Risk Management John Walz VP Technical and Conferences Activities, IEEE Computer Society Vice-Chair Planning...Software & Systems Engineering Standards Committee, IEEE Computer Society US TAG to ISO TMB Risk Management Working Group Systems and Software

  18. Analysis of Global Properties of Shapes

    DTIC Science & Technology

    2010-06-01

    Conference on Computer Vision (ICCV) ( Bejing , China , 2005), IEEE. [113] Thrun, S., and Wegbreit, B. Shape from symmetry. In Proceedings of the...International Conference on Computer Vision (ICCV) ( Bejing , China , 2005), IEEE. [114] Toshev, A., Shi, J., and Daniilidis, K. Image matching via saliency...applications ranging from sampling points to finding correspondences to shape simplification. Discrete variants of the Laplace-Beltrami opera - tor [108] and

  19. High-precision arithmetic in mathematical physics

    DOE PAGES

    Bailey, David H.; Borwein, Jonathan M.

    2015-05-12

    For many scientific calculations, particularly those involving empirical data, IEEE 32-bit floating-point arithmetic produces results of sufficient accuracy, while for other applications IEEE 64-bit floating-point is more appropriate. But for some very demanding applications, even higher levels of precision are often required. Furthermore, this article discusses the challenge of high-precision computation, in the context of mathematical physics, and highlights what facilities are required to support future computation, in light of emerging developments in computer architecture.

  20. Election Verifiability: Cryptographic Definitions and an Analysis of Helios and JCJ

    DTIC Science & Technology

    2015-04-01

    anonymous credentials. In CSF’14: 27th Computer Security Foundations Symposium. IEEE Computer Society, 2014. To appear. [22] David Chaum . Untraceable...electronic mail, return addresses, and digital pseudonyms. Communications of the ACM, 24(2):84–88, 1981. [23] David Chaum . Secret-ballot receipts...True voter-verifiable elections. IEEE Security and Privacy, 2(1):38–47, 2004. [24] David Chaum , Richard Carback, Jeremy Clark, Aleksander Essex, Stefan

  1. 49 CFR 395.18 - Matter incorporated by reference.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Technology—Telecommunications and information exchange between systems—Local and metropolitan area networks...) Specifications,” IEEE Computer Society, Sponsored by the LAN/MAN Standards Committee: June 12, 2007 (IEEE Std... 446-2008, American National Standard for Information Technology—Identifying Attributes for Named...

  2. Effects of Computer Architecture on FFT (Fast Fourier Transform) Algorithm Performance.

    DTIC Science & Technology

    1983-12-01

    Criteria for Efficient Implementation of FFT Algorithms," IEEE Transactions on Acoustics, Speech, and Signal Processing, Vol. ASSP-30, pp. 107-109, Feb...1982. Burrus, C. S. and P. W. Eschenbacher. "An In-Place, In-Order Prime Factor FFT Algorithm," IEEE Transactions on Acoustics, Speech, and Signal... Transactions on Acoustics, Speech, and Signal Processing, Vol. ASSP-30, pp. 217-226, Apr. 1982. Control Data Corporation. CDC Cyber 170 Computer Systems

  3. An Infrastructure for Multi-Level Secure Service-Oriented Architecture (MLS-SOA) Using the Multiple Single-Level Approach

    DTIC Science & Technology

    2009-12-17

    IEEE TDKE, 1996. 8( 1). 14. Garvey, T.D., The inference Problem for Computer Security. 1992, SRI International. 15. Chaum , D ., Blind Signatures for...Pervasive Computing Environments. IEEE Transactions on Vehicular Technology, 2006. 55(4). 17. Chaum , D ., Security without Identification: Transaction...Systems to make Big Brother Obsolete. Communications of the ACM 1985. 28(10). 18. Chaum , D ., Untraceable Electronic Mail, Return Addresses, and Digital

  4. Semiconductor Nanowire and Nanoribbon Thermoelectrics: A Comprehensive Computational Study

    DTIC Science & Technology

    2013-05-01

    August 17-20, 2010). Available online through IEEE Xplore . http://dx.doi.org/10.1109/NANO.2010.5698047 4. Z. Aksamija and I. Knezevic...Korea (August 17-20, 2010). Available online through IEEE Xplore . http://dx.doi.org/10.1109/NANO.2010.5697827 5. D. Vasileska, K. Raleva, S. M...IWCE 2010) Available online through IEEE Xplore , http://dx.doi.org/10.1109/IWCE.2010.5677916 6. E. B. Ramayya and I. Knezevic, “Ultrascaled

  5. Performance of the Sleep-Mode Mechanism of the New IEEE 802.16m Proposal for Correlated Downlink Traffic

    NASA Astrophysics Data System (ADS)

    de Turck, Koen; de Vuyst, Stijn; Fiems, Dieter; Wittevrongel, Sabine; Bruneel, Herwig

    There is a considerable interest nowadays in making wireless telecommunication more energy-efficient. The sleep-mode mechanism in WiMAX (IEEE 802.16e) is one of such energy saving measures. Recently, Samsung proposed some modifications on the sleep-mode mechanism, scheduled to appear in the forthcoming IEEE 802.16m standard, aimed at minimizing the signaling overhead. In this work, we present a performance analysis of this proposal and clarify the differences with the standard mechanism included in IEEE 802.16e. We also propose some special algorithms aimed at reducing the computational complexity of the analysis.

  6. Large-scale parallel genome assembler over cloud computing environment.

    PubMed

    Das, Arghya Kusum; Koppa, Praveen Kumar; Goswami, Sayan; Platania, Richard; Park, Seung-Jong

    2017-06-01

    The size of high throughput DNA sequencing data has already reached the terabyte scale. To manage this huge volume of data, many downstream sequencing applications started using locality-based computing over different cloud infrastructures to take advantage of elastic (pay as you go) resources at a lower cost. However, the locality-based programming model (e.g. MapReduce) is relatively new. Consequently, developing scalable data-intensive bioinformatics applications using this model and understanding the hardware environment that these applications require for good performance, both require further research. In this paper, we present a de Bruijn graph oriented Parallel Giraph-based Genome Assembler (GiGA), as well as the hardware platform required for its optimal performance. GiGA uses the power of Hadoop (MapReduce) and Giraph (large-scale graph analysis) to achieve high scalability over hundreds of compute nodes by collocating the computation and data. GiGA achieves significantly higher scalability with competitive assembly quality compared to contemporary parallel assemblers (e.g. ABySS and Contrail) over traditional HPC cluster. Moreover, we show that the performance of GiGA is significantly improved by using an SSD-based private cloud infrastructure over traditional HPC cluster. We observe that the performance of GiGA on 256 cores of this SSD-based cloud infrastructure closely matches that of 512 cores of traditional HPC cluster.

  7. Single-pixel computational ghost imaging with helicity-dependent metasurface hologram.

    PubMed

    Liu, Hong-Chao; Yang, Biao; Guo, Qinghua; Shi, Jinhui; Guan, Chunying; Zheng, Guoxing; Mühlenbernd, Holger; Li, Guixin; Zentgraf, Thomas; Zhang, Shuang

    2017-09-01

    Different optical imaging techniques are based on different characteristics of light. By controlling the abrupt phase discontinuities with different polarized incident light, a metasurface can host a phase-only and helicity-dependent hologram. In contrast, ghost imaging (GI) is an indirect imaging modality to retrieve the object information from the correlation of the light intensity fluctuations. We report single-pixel computational GI with a high-efficiency reflective metasurface in both simulations and experiments. Playing a fascinating role in switching the GI target with different polarized light, the metasurface hologram generates helicity-dependent reconstructed ghost images and successfully introduces an additional security lock in a proposed optical encryption scheme based on the GI. The robustness of our encryption scheme is further verified with the vulnerability test. Building the first bridge between the metasurface hologram and the GI, our work paves the way to integrate their applications in the fields of optical communications, imaging technology, and security.

  8. Single-pixel computational ghost imaging with helicity-dependent metasurface hologram

    PubMed Central

    Liu, Hong-Chao; Yang, Biao; Guo, Qinghua; Shi, Jinhui; Guan, Chunying; Zheng, Guoxing; Mühlenbernd, Holger; Li, Guixin; Zentgraf, Thomas; Zhang, Shuang

    2017-01-01

    Different optical imaging techniques are based on different characteristics of light. By controlling the abrupt phase discontinuities with different polarized incident light, a metasurface can host a phase-only and helicity-dependent hologram. In contrast, ghost imaging (GI) is an indirect imaging modality to retrieve the object information from the correlation of the light intensity fluctuations. We report single-pixel computational GI with a high-efficiency reflective metasurface in both simulations and experiments. Playing a fascinating role in switching the GI target with different polarized light, the metasurface hologram generates helicity-dependent reconstructed ghost images and successfully introduces an additional security lock in a proposed optical encryption scheme based on the GI. The robustness of our encryption scheme is further verified with the vulnerability test. Building the first bridge between the metasurface hologram and the GI, our work paves the way to integrate their applications in the fields of optical communications, imaging technology, and security. PMID:28913433

  9. Memorias Conferencia Internacional IEEE Mexico 1971, Sobre Sistemas, Redes Y Computadoras. Volumen I and Volumen II. (Proceedings of International Conference of IEEE Concerning Systems, Networks, and Computers. Volume I and Volume II.

    ERIC Educational Resources Information Center

    Concheiro, A. Alonso, Ed.; And Others

    The following papers in English from this international conference may be of particular interest to those in the field of education. T. Nakahara, A. Tsukamota, and M. Matsumoto describe a computer-aided design technique for an economical urban cable television system. W. D. Wasson and R. K. Chitkara outline a recognition scheme based on analysis…

  10. A Monocular SLAM Method to Estimate Relative Pose During Satellite Proximity Operations

    DTIC Science & Technology

    2015-03-26

    localization and mapping with efficient outlier handling. In The IEEE Conference on Computer Vision and Pattern Recognition (CVPR), June 2013. 5. Herbert Bay...S.H. Spencer . Next generation advanced video guidance sensor. In Aerospace Conference, 2008 IEEE, pages 1–8, March 2008. 12. Michael Calonder, Vincent

  11. Developing a Qualia-Based Multi-Agent Architecture for Use in Malware Detection

    DTIC Science & Technology

    2010-03-01

    executables were correctly classified with a 6% false positive rate [7]. Kolter and Maloof expand Schultz’s work by analyzing different...Proceedings of the 2001 IEEE Symposium on Security and Privacy. Los Alamitos, CA: IEEE Computer Society, 2001. [8] J. Z. Kolter and M. A. Maloof

  12. New IEEE standard enables data collection for medical applications.

    PubMed

    Kennelly, R J; Wittenber, J

    1994-01-01

    The IEEE has gone to ballot on a "Standard for Medical Device Communications", IEEE P1073. The lower layer, hardware portions of the standard are expected to be approved by the IEEE Standards Board at their December 11-13, 1994 meeting. Other portions of the standard are in the initial stages of the IEEE ballot process. The intent of the standard is to allow hospitals and other users to interface medical electronic devices to host computer systems in a standard, interchangeable manner. The standard is optimized for acute care environments such as ICU's, operating rooms, and emergency rooms. [1] IEEE General Committee and Subcommittee work has been on-going since 1984. Significant amounts of work have been done to discover and meet the needs of the patient care setting. Surveys performed in 1989 identified the following four key user requirements for medical device communications: 1) Frequent reconfiguration of the network. 2) Allow "plug and play" operation by users. 3) Associate devices with a specific bed and patient. 4) Support a wide range of hospital computer system topologies. Additionally, the most critical difference in the acute care setting is patient safety, which has an overall effect on the standard. The standard that went to ballot meets these requirements. The standard is based on existing ISO standards. P1073 is compliant with the OSI seven layer model. P1073 specifies the entire communication stack, from object-oriented software to hospital unique connectors. The standard will be able to be put forward as a true international standard, much in the way that the IEEE 802.x family of standards (like Ethernet) were presented as draft ISO standards.(ABSTRACT TRUNCATED AT 250 WORDS)

  13. Genomics, molecular imaging, bioinformatics, and bio-nano-info integration are synergistic components of translational medicine and personalized healthcare research.

    PubMed

    Yang, Jack Y; Yang, Mary Qu; Arabnia, Hamid R; Deng, Youping

    2008-09-16

    Supported by National Science Foundation (NSF), International Society of Intelligent Biological Medicine (ISIBM), International Journal of Computational Biology and Drug Design and International Journal of Functional Informatics and Personalized Medicine, IEEE 7th Bioinformatics and Bioengineering attracted more than 600 papers and 500 researchers and medical doctors. It was the only synergistic inter/multidisciplinary IEEE conference with 24 Keynote Lectures, 7 Tutorials, 5 Cutting-Edge Research Workshops and 32 Scientific Sessions including 11 Special Research Interest Sessions that were designed dynamically at Harvard in response to the current research trends and advances. The committee was very grateful for the IEEE Plenary Keynote Lectures given by: Dr. A. Keith Dunker (Indiana), Dr. Jun Liu (Harvard), Dr. Brian Athey (Michigan), Dr. Mark Borodovsky (Georgia Tech and President of ISIBM), Dr. Hamid Arabnia (Georgia and Vice-President of ISIBM), Dr. Ruzena Bajcsy (Berkeley and Member of United States National Academy of Engineering and Member of United States Institute of Medicine of the National Academies), Dr. Mary Yang (United States National Institutes of Health and Oak Ridge, DOE), Dr. Chih-Ming Ho (UCLA and Member of United States National Academy of Engineering and Academician of Academia Sinica), Dr. Andy Baxevanis (United States National Institutes of Health), Dr. Arif Ghafoor (Purdue), Dr. John Quackenbush (Harvard), Dr. Eric Jakobsson (UIUC), Dr. Vladimir Uversky (Indiana), Dr. Laura Elnitski (United States National Institutes of Health) and other world-class scientific leaders. The Harvard meeting was a large academic event 100% full-sponsored by IEEE financially and academically. After a rigorous peer-review process, the committee selected 27 high-quality research papers from 600 submissions. The committee is grateful for contributions from keynote speakers Dr. Russ Altman (IEEE BIBM conference keynote lecturer on combining simulation and machine learning to recognize function in 4D), Dr. Mary Qu Yang (IEEE BIBM workshop keynote lecturer on new initiatives of detecting microscopic disease using machine learning and molecular biology, http://ieeexplore.ieee.org/servlet/opac?punumber=4425386) and Dr. Jack Y. Yang (IEEE BIBM workshop keynote lecturer on data mining and knowledge discovery in translational medicine) from the first IEEE Computer Society BioInformatics and BioMedicine (IEEE BIBM) international conference and workshops, November 2-4, 2007, Silicon Valley, California, USA.

  14. Genomics, molecular imaging, bioinformatics, and bio-nano-info integration are synergistic components of translational medicine and personalized healthcare research

    PubMed Central

    2008-01-01

    Supported by National Science Foundation (NSF), International Society of Intelligent Biological Medicine (ISIBM), International Journal of Computational Biology and Drug Design and International Journal of Functional Informatics and Personalized Medicine, IEEE 7th Bioinformatics and Bioengineering attracted more than 600 papers and 500 researchers and medical doctors. It was the only synergistic inter/multidisciplinary IEEE conference with 24 Keynote Lectures, 7 Tutorials, 5 Cutting-Edge Research Workshops and 32 Scientific Sessions including 11 Special Research Interest Sessions that were designed dynamically at Harvard in response to the current research trends and advances. The committee was very grateful for the IEEE Plenary Keynote Lectures given by: Dr. A. Keith Dunker (Indiana), Dr. Jun Liu (Harvard), Dr. Brian Athey (Michigan), Dr. Mark Borodovsky (Georgia Tech and President of ISIBM), Dr. Hamid Arabnia (Georgia and Vice-President of ISIBM), Dr. Ruzena Bajcsy (Berkeley and Member of United States National Academy of Engineering and Member of United States Institute of Medicine of the National Academies), Dr. Mary Yang (United States National Institutes of Health and Oak Ridge, DOE), Dr. Chih-Ming Ho (UCLA and Member of United States National Academy of Engineering and Academician of Academia Sinica), Dr. Andy Baxevanis (United States National Institutes of Health), Dr. Arif Ghafoor (Purdue), Dr. John Quackenbush (Harvard), Dr. Eric Jakobsson (UIUC), Dr. Vladimir Uversky (Indiana), Dr. Laura Elnitski (United States National Institutes of Health) and other world-class scientific leaders. The Harvard meeting was a large academic event 100% full-sponsored by IEEE financially and academically. After a rigorous peer-review process, the committee selected 27 high-quality research papers from 600 submissions. The committee is grateful for contributions from keynote speakers Dr. Russ Altman (IEEE BIBM conference keynote lecturer on combining simulation and machine learning to recognize function in 4D), Dr. Mary Qu Yang (IEEE BIBM workshop keynote lecturer on new initiatives of detecting microscopic disease using machine learning and molecular biology, http://ieeexplore.ieee.org/servlet/opac?punumber=4425386) and Dr. Jack Y. Yang (IEEE BIBM workshop keynote lecturer on data mining and knowledge discovery in translational medicine) from the first IEEE Computer Society BioInformatics and BioMedicine (IEEE BIBM) international conference and workshops, November 2-4, 2007, Silicon Valley, California, USA. PMID:18831773

  15. 76 FR 67257 - Computer Matching Program Between the Department of Veterans Affairs (VA) and the Department of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-31

    ... for or who are receiving education benefit payments under the Montgomery GI Bill. The purpose of the... for and/or are receiving, or have received education benefit payments under the Post-9/11 GI Bill... of Defense with VA records of benefit recipients under the Montgomery GI Bill. The goal of these...

  16. IEEE Conference on Software Engineering Education and Training (CSEE&T 2012) Proceedings (25th, Nanjing, Jiangsu, China, April 17-19, 2012)

    ERIC Educational Resources Information Center

    IEEE Conference on Software Engineering Education and Training, Proceedings (MS), 2012

    2012-01-01

    The Conference on Software Engineering Education and Training (CSEE&T) is the premier international peer-reviewed conference, sponsored by the Institute of Electrical and Electronics Engineers, Inc. (IEEE) Computer Society, which addresses all major areas related to software engineering education, training, and professionalism. This year, as…

  17. Design of an Information Technology Undergraduate Program to Produce IT Versatilists

    ERIC Educational Resources Information Center

    Koohang, Alex; Riley, Liz; Smith, Terry; Floyd, Kevin

    2010-01-01

    This paper attempts to present a model for designing an IT undergraduate program that is based on the recommendations of the Association for Computer Machinery/Institute of Electrical and Electronics Engineers--Information Technology (ACM/IEEE--IT) Curriculum Model. The main intent is to use the ACM/IEEE--IT Curriculum Model's recommendations as a…

  18. An Authentication and Key Management Mechanism for Resource Constrained Devices in IEEE 802.11-based IoT Access Networks.

    PubMed

    Kim, Ki-Wook; Han, Youn-Hee; Min, Sung-Gi

    2017-09-21

    Many Internet of Things (IoT) services utilize an IoT access network to connect small devices with remote servers. They can share an access network with standard communication technology, such as IEEE 802.11ah. However, an authentication and key management (AKM) mechanism for resource constrained IoT devices using IEEE 802.11ah has not been proposed as yet. We therefore propose a new AKM mechanism for an IoT access network, which is based on IEEE 802.11 key management with the IEEE 802.1X authentication mechanism. The proposed AKM mechanism does not require any pre-configured security information between the access network domain and the IoT service domain. It considers the resource constraints of IoT devices, allowing IoT devices to delegate the burden of AKM processes to a powerful agent. The agent has sufficient power to support various authentication methods for the access point, and it performs cryptographic functions for the IoT devices. Performance analysis shows that the proposed mechanism greatly reduces computation costs, network costs, and memory usage of the resource-constrained IoT device as compared to the existing IEEE 802.11 Key Management with the IEEE 802.1X authentication mechanism.

  19. An Authentication and Key Management Mechanism for Resource Constrained Devices in IEEE 802.11-based IoT Access Networks

    PubMed Central

    Han, Youn-Hee; Min, Sung-Gi

    2017-01-01

    Many Internet of Things (IoT) services utilize an IoT access network to connect small devices with remote servers. They can share an access network with standard communication technology, such as IEEE 802.11ah. However, an authentication and key management (AKM) mechanism for resource constrained IoT devices using IEEE 802.11ah has not been proposed as yet. We therefore propose a new AKM mechanism for an IoT access network, which is based on IEEE 802.11 key management with the IEEE 802.1X authentication mechanism. The proposed AKM mechanism does not require any pre-configured security information between the access network domain and the IoT service domain. It considers the resource constraints of IoT devices, allowing IoT devices to delegate the burden of AKM processes to a powerful agent. The agent has sufficient power to support various authentication methods for the access point, and it performs cryptographic functions for the IoT devices. Performance analysis shows that the proposed mechanism greatly reduces computation costs, network costs, and memory usage of the resource-constrained IoT device as compared to the existing IEEE 802.11 Key Management with the IEEE 802.1X authentication mechanism. PMID:28934152

  20. A Strategy for Improved System Assurance

    DTIC Science & Technology

    2007-06-20

    Quality (Measurements Life Cycle Safety, Security & Others) ISO /IEC 12207 * Software Life Cycle Processes ISO 9001 Quality Management System...14598 Software Product Evaluation Related ISO /IEC 90003 Guidelines for the Application of ISO 9001:2000 to Computer Software IEEE 12207 Industry...Implementation of International Standard ISO /IEC 12207 IEEE 1220 Standard for Application and Management of the System Engineering Process Use in

  1. Creating a New Model Curriculum: A Rationale for "Computing Curricula 1990".

    ERIC Educational Resources Information Center

    Bruce, Kim B.

    1991-01-01

    Describes a model for the design of undergraduate curricula in the discipline of computing that was developed by the ACM/IEEE (Association for Computing Machinery/Institute of Electrical and Electronics Engineers) Computer Society Joint Curriculum Task Force. Institutional settings and structures in which computing degrees are awarded are…

  2. Mache: No-Loss Trace Compaction

    DTIC Science & Technology

    1988-09-15

    Data Compression . IEEE Computer 176 (June 1984), 8-19. 10. ZIV , J. AND LEMPEL , A. A Universal Algorithm for Sequential Data Com- pression. IEEE... compression scheme which takes ad- vantage of repeating patterns in the sequence of bytes. I have used the Lempel - Ziv compression algorithm [9,10,11...Transactions on Information Theory 23 (1976), 75-81. 11. ZIV , J. AND LEMPEL , A. Compression of Individual Sequences via Variable-

  3. Advanced Numerical Techniques of Performance Evaluation. Volume 1

    DTIC Science & Technology

    1990-06-01

    system scheduling3thread. The scheduling thread then runs any other ready thread that can be found. A thread can only sleep or switch out on itself...Polychronopoulos and D.J. Kuck. Guided Self- Scheduling : A Practical Scheduling Scheme for Parallel Supercomputers. IEEE Transactions on Computers C...Kuck 1987] C.D. Polychronopoulos and D.J. Kuck. Guided Self- Scheduling : A Practical Scheduling Scheme for Parallel Supercomputers. IEEE Trans. on Comp

  4. Real-Time-Simulation of IEEE-5-Bus Network on OPAL-RT-OP4510 Simulator

    NASA Astrophysics Data System (ADS)

    Atul Bhandakkar, Anjali; Mathew, Lini, Dr.

    2018-03-01

    The Real-Time Simulator tools have high computing technologies, improved performance. They are widely used for design and improvement of electrical systems. The advancement of the software tools like MATLAB/SIMULINK with its Real-Time Workshop (RTW) and Real-Time Windows Target (RTWT), real-time simulators are used extensively in many engineering fields, such as industry, education, and research institutions. OPAL-RT-OP4510 is a Real-Time Simulator which is used in both industry and academia. In this paper, the real-time simulation of IEEE-5-Bus network is carried out by means of OPAL-RT-OP4510 with CRO and other hardware. The performance of the network is observed with the introduction of fault at various locations. The waveforms of voltage, current, active and reactive power are observed in the MATLAB simulation environment and on the CRO. Also, Load Flow Analysis (LFA) of IEEE-5-Bus network is computed using MATLAB/Simulink power-gui load flow tool.

  5. Interface Provides Standard-Bus Communication

    NASA Technical Reports Server (NTRS)

    Culliton, William G.

    1995-01-01

    Microprocessor-controlled interface (IEEE-488/LVABI) incorporates service-request and direct-memory-access features. Is circuit card enabling digital communication between system called "laser auto-covariance buffer interface" (LVABI) and compatible personal computer via general-purpose interface bus (GPIB) conforming to Institute for Electrical and Electronics Engineers (IEEE) Standard 488. Interface serves as second interface enabling first interface to exploit advantages of GPIB, via utility software written specifically for GPIB. Advantages include compatibility with multitasking and support of communication among multiple computers. Basic concept also applied in designing interfaces for circuits other than LVABI for unidirectional or bidirectional handling of parallel data up to 16 bits wide.

  6. Computer tomographic evaluation of digestive tract non-Hodgkin lymphomas.

    PubMed

    Lupescu, Ioana G; Grasu, Mugur; Goldis, Gheorghe; Popa, Gelu; Gheorghe, Cristian; Vasilescu, Catalin; Moicean, Andreea; Herlea, Vlad; Georgescu, Serban A

    2007-09-01

    Computer Tomographic (CT) study is crucial for defining distribution, characteristics and staging of primary gastrointestinal lymphomas. The presence of multifocal sites, the wall thickening with diffuse infiltration of the affected gastrointestinal (GI) segment in association with regional adenopathies, permit the orientation of the CT diagnosis for primary GI lymphomas. The gold standard for diagnosis remains, in all cases of digestive tract non-Hodgkin lymphomas (NHL), the histological examination, which allows a tissue diagnosis, performed preferably by transmural biopsy.

  7. An Approach to Noise Reduction in Human Skin Admittance Measurements

    DTIC Science & Technology

    2001-10-25

    1966, 4, 439-449. [ 4] D. H. Gordon, "Triboelectric interference in the ECG", IEEE Trans., 1975, BME -22, 252-255. [ 5] J. C. Huhta and J. G...Webster, ඄-Hz interference in electrocardiography", IEEE Trans., 1973, BME -20, 91-101. [ 6] S. Grimnes, "Electrovibration, cutaneous sensation of...this period he has published two textbooks about UNIX and Shell Programming, and concentrated at computer simulation and digital signal processing

  8. Privacy Analysis of the Internet Protocol

    DTIC Science & Technology

    2002-12-01

    mixing approach first proposed for e-mail by David Chaum [Cha81]. The Onion Routing system maintains a set of mixing centers called onion routers...IEEE Computer, vol. 33, no. 5, pp. 59-67, May, 2000. 5. [Cha81] Chaum , D., Untraceable Electronic Mail, Return Addresses, and Digital Pseudonyms...the Internet,” Proceedings of IEEE COMPCON, 1997. 11. [Gol99] Goldschlag, David M., Reed, Michael G., and Syverson, Paul F., “Onion Routing for

  9. Parametric Study of Beta-Endpoint Energy in Direct Energy Converters

    DTIC Science & Technology

    2007-01-01

    Circuits for Ultra-high Efficiency Micro- power Generators using Nickel-63 Radioisotope . Technical Digest, ISSCC, February 2006, 418– 19. 8. Lal, A...Zakar, E.; Dubey, M.; Lal, A. MEMS Radioisotope - powered Piezoelectric Power Generator. IEEE MEMS 2006, Istanbul, Turkey, January 2006, 94–97. 16... Power : A Radioisotope - powered Piezoelectric Generator. IEEE Pervasive Computing Jan-Mar 2005, 4 (1), 53–61. Lee, C.; Guo, H.; Radhakrishnan, S.; Lal, A

  10. The GI Project: a prototype electronic textbook for high school biology.

    PubMed

    Calhoun, P S; Fishman, E K

    1997-01-01

    A prototype electronic science textbook for secondary education was developed to help bridge the gap between state-of-the-art medical technology and the basic science classroom. The prototype combines the latest in radiologic imaging techniques with a user-friendly multimedia computer program to teach the anatomy, physiology, and diseases of the gastrointestinal (GI) tract. The program includes original text, illustrations, photographs, animations, images from upper GI studies, plain radiographs, computed tomographic images, and three-dimensional reconstructions. These features are intended to create a stimulus-rich environment in which the high school science student can enjoy a variety of interactive experiences that will facilitate the learning process. The computer-based book is a new educational tool that promises to play a prominent role in the coming years. Current research suggests that computer-based books are valuable as an alternative educational medium. Although it is not yet clear what form textbooks will take in the future, computer-based books are already proving valuable as an alternative educational medium. For beginning students, they reinforce the material found in traditional textbooks and class presentations; for advanced students, they provide motivation to learn outside the traditional classroom.

  11. 77 FR 75499 - Privacy Act of 1974: Computer Matching Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-20

    ... education benefit payments under the Montgomery GI Bill and Post-9/11 GI Bill. The purpose of the match is... have applied for and/or are receiving, or have received education benefit payments under the Montgomery... and Legislative Development Team Leader, Education Service (225B), Veterans Benefits Administration...

  12. Identifying Green Infrastructure from Social Media and Crowdsourcing- An Image Based Machine-Learning Approach.

    NASA Astrophysics Data System (ADS)

    Rai, A.; Minsker, B. S.

    2016-12-01

    In this work we introduce a novel dataset GRID: GReen Infrastructure Detection Dataset and a framework for identifying urban green storm water infrastructure (GI) designs (wetlands/ponds, urban trees, and rain gardens/bioswales) from social media and satellite aerial images using computer vision and machine learning methods. Along with the hydrologic benefits of GI, such as reducing runoff volumes and urban heat islands, GI also provides important socio-economic benefits such as stress recovery and community cohesion. However, GI is installed by many different parties and cities typically do not know where GI is located, making study of its impacts or siting new GI difficult. We use object recognition learning methods (template matching, sliding window approach, and Random Hough Forest method) and supervised machine learning algorithms (e.g., support vector machines) as initial screening approaches to detect potential GI sites, which can then be investigated in more detail using on-site surveys. Training data were collected from GPS locations of Flickr and Instagram image postings and Amazon Mechanical Turk identification of each GI type. Sliding window method outperformed other methods and achieved an average F measure, which is combined metric for precision and recall performance measure of 0.78.

  13. High performance optical encryption based on computational ghost imaging with QR code and compressive sensing technique

    NASA Astrophysics Data System (ADS)

    Zhao, Shengmei; Wang, Le; Liang, Wenqiang; Cheng, Weiwen; Gong, Longyan

    2015-10-01

    In this paper, we propose a high performance optical encryption (OE) scheme based on computational ghost imaging (GI) with QR code and compressive sensing (CS) technique, named QR-CGI-OE scheme. N random phase screens, generated by Alice, is a secret key and be shared with its authorized user, Bob. The information is first encoded by Alice with QR code, and the QR-coded image is then encrypted with the aid of computational ghost imaging optical system. Here, measurement results from the GI optical system's bucket detector are the encrypted information and be transmitted to Bob. With the key, Bob decrypts the encrypted information to obtain the QR-coded image with GI and CS techniques, and further recovers the information by QR decoding. The experimental and numerical simulated results show that the authorized users can recover completely the original image, whereas the eavesdroppers can not acquire any information about the image even the eavesdropping ratio (ER) is up to 60% at the given measurement times. For the proposed scheme, the number of bits sent from Alice to Bob are reduced considerably and the robustness is enhanced significantly. Meantime, the measurement times in GI system is reduced and the quality of the reconstructed QR-coded image is improved.

  14. A Computational Model and Multi-Agent Simulation for Information Assurance

    DTIC Science & Technology

    2002-06-01

    Podell , Information Security: an Integrated Collection of Essays, IEEE Computer Society Press, Los Alamitos, CA, 1994. Brinkley, D. L. and Schell, R...R., “What is There to Worry About? An Introduction to the Computer Security Problem,” ed. Abrams and Jajodia and Podell , Information Security: an

  15. A Survey of Parallel Computing

    DTIC Science & Technology

    1988-07-01

    Evaluating Two Massively Parallel Machines. Communications of the ACM .9, , , 176 BIBLIOGRAPHY 29, 8 (August), pp. 752-758. Gajski , D.D., Padua, D.A., Kuck...Computer Architecture, edited by Gajski , D. D., Milutinovic, V. M. Siegel, H. J. and Furht, B. P. IEEE Computer Society Press, Washington, D.C., pp. 387-407

  16. Lower gastrointestinal bleeding: Role of 64-row computed tomographic angiography in diagnosis and therapeutic planning

    PubMed Central

    Ren, Jian-Zhuang; Zhang, Meng-Fan; Rong, Ai-Mei; Fang, Xiang-Jie; Zhang, Kai; Huang, Guo-Hao; Chen, Peng-Fei; Wang, Zhao-Yang; Duan, Xu-Hua; Han, Xin-Wei; Liu, Yan-Jie

    2015-01-01

    AIM: To determine the value of computed tomographic angiography (CTA) for diagnosis and therapeutic planning in lower gastrointestinal (GI) bleeding. METHODS: Sixty-three consecutive patients with acute lower GI bleeding underwent CTA before endovascular or surgical treatment. CTA was used to determine whether the lower GI bleeding was suitable for endovascular treatment, surgical resection, or conservative treatment in each patient. Treatment planning with CTA was compared with actual treatment decisions or endovascular or surgical treatment that had been carried out in each patient based on CTA findings. RESULTS: 64-row CTA detected active extravasation of contrast material in 57 patients and six patients had no demonstrable active bleeding, resulting in an accuracy of 90.5% in the detection of acute GI bleeding (57 of 63). In three of the six patients with no demonstrable active bleeding, active lower GI bleeding recurred within one week after CTA, and angiography revealed acute bleeding. The overall location-based accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for the detection of GI bleeding by 64-row CTA were 98.8% (249 of 252), 95.0% (57 of 60), 100% (192 of 192), 100% (57 of 57), and 98.5% (192 of 195), respectively. Treatment planning was correctly established on the basis of 64-row CTA with an accuracy, sensitivity, specificity, PPV and NPV of 98.4% (248 of 252), 93.3% (56 of 60), 100% (192 of 192), 100% (56 of 56), and 97.5% (192 of 196), respectively, in a location-based evaluation. CONCLUSION: 64-row CTA is safe and effective in making decisions regarding treatment, without performing digital subtraction angiography or surgery, in the majority of patients with lower GI bleeding. PMID:25852291

  17. Adaptive Topological Configuration of an Integrated Circuit/Packet-Switched Computer Network.

    DTIC Science & Technology

    1984-01-01

    Gitman et al. [45] state that there are basically two approaches to the integrated network design problem: (1) solve the link/capacity problem for...1972), 1385-1397. 33. Frank, H., and Gitman , I. Economic analysis of integrated voice and data networks: a case study. Proc. of IEEE 66 , 11 (Nov. 1978...1974), 1074-1079. 45. Gitman , I., Hsieh, W., and Occhiogrosso, B. J. Analysis and design of hybrid switching networks. IEEE Trans. on Comm. Com-29

  18. Performance of Wireless Unattended Sensor Network in Maritime Applications

    DTIC Science & Technology

    2007-06-01

    longevity. Crossbow Technologies produces a number of gateways for use with their motes which include the MIB510, the MIB600 and the Stargate . The...MIB510 and MIB600 gateways require interface directly with a PC while he Stargate gateway interfaces remotely using the IEEE 802.11 standard for access...dedicated PC is unfeasible, the Stargate gateway allows remote access using the IEEE 802.11 standard. This can be accomplished via a Personal Computer

  19. Neurale Netwerken en Radarsystemen (Neural Networks and Radar Systems)

    DTIC Science & Technology

    1989-08-01

    general issues in cognitive science", Parallel distributed processing, Vol 1: Foundations, Rumelhart et al. 1986 pp 110-146 THO rapport Pagina 151 36 D.E...34Neural networks (part 2)",Expert Focus, IEEE Expert, Spring 1988. 61 J.A. Anderson, " Cognitive and Psychological Computations with Neural Models", IEEE...Pagina 154 69 David H. Ackley, Geoffrey E. Hinton and Terrence J. Sejnowski, "A Learning Algorithm for Boltzmann machines", cognitive science 9, 147-169

  20. Transmission Loss Calculation using A and B Loss Coefficients in Dynamic Economic Dispatch Problem

    NASA Astrophysics Data System (ADS)

    Jethmalani, C. H. Ram; Dumpa, Poornima; Simon, Sishaj P.; Sundareswaran, K.

    2016-04-01

    This paper analyzes the performance of A-loss coefficients while evaluating transmission losses in a Dynamic Economic Dispatch (DED) Problem. The performance analysis is carried out by comparing the losses computed using nominal A loss coefficients and nominal B loss coefficients in reference with load flow solution obtained by standard Newton-Raphson (NR) method. Density based clustering method based on connected regions with sufficiently high density (DBSCAN) is employed in identifying the best regions of A and B loss coefficients. Based on the results obtained through cluster analysis, a novel approach in improving the accuracy of network loss calculation is proposed. Here, based on the change in per unit load values between the load intervals, loss coefficients are updated for calculating the transmission losses. The proposed algorithm is tested and validated on IEEE 6 bus system, IEEE 14 bus, system IEEE 30 bus system and IEEE 118 bus system. All simulations are carried out using SCILAB 5.4 (www.scilab.org) which is an open source software.

  1. Outcome Following a Negative CT Angiogram for Gastrointestinal Hemorrhage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chan, Victoria, E-mail: drvictoriac@gmail.com; Tse, Donald, E-mail: donald.tse@gmail.com; Dixon, Shaheen, E-mail: shaheen7noorani@gmail.com

    2015-04-15

    ObjectiveThis study was designed to evaluate the role of a negative computed tomography angiogram (CTA) in patients who present with gastrointestinal (GI) hemorrhage.MethodsA review of all patients who had CTAs for GI hemorrhage over an 8-year period from January 2005 to December 2012 was performed. Data for patient demographics, location of hemorrhage, hemodynamic stability, and details of angiograms and/or the embolization procedure were obtained from the CRIS/PACS database, interventional radiology database, secure electronic medical records, and patient’s clinical notes.ResultsA total of 180 patients had 202 CTAs during the 8-year period: 87 CTAs were performed for upper GI hemorrhage (18 positivemore » for active bleeding, 69 negative) and 115 for lower GI hemorrhage (37 positive for active bleeding, 78 negative); 58.7 % (37/63) of patients with upper GI bleed and 77.4 % (48/62) of patients with lower GI bleed who had an initial negative CTA did not rebleed without the need for radiological or surgical intervention. This difference was statistically significant (p = 0.04). The relative risk of rebleeding, following a negative CTA, in lower GI bleeding versus upper GI bleeding patients is 0.55 (95 % confidence interval 0.32–0.95).ConclusionsPatients with upper GI bleed who had negative CTAs usually require further intervention to stop the bleeding. In contrast, most patients presenting with lower GI hemorrhage who had a negative first CTA were less likely to rebleed.« less

  2. Trusted Network Interpretation of the Trusted Computer System Evaluation Criteria. Version 1.

    DTIC Science & Technology

    1987-07-01

    for Secure Computer Systema, MTR-3153, The MITRE Corporation, Bedford, MA, June 1975. 1 See, for example, M. D. Abrams and H. J. Podell , Tutorial...References References Abrams, M. D. and H. J. Podell , Tutorial: Computer and Network Security, IEEE Com- puter Society Press, 1987. Addendum to the

  3. The Computer-Job Salary Picture.

    ERIC Educational Resources Information Center

    Basta, Nicholas

    1987-01-01

    Discusses starting salaries for graduates with various degrees in computer science and electrical engineering. Summarizes the results of a recent study by the Institute of Electrical and Electronics Engineers (IEEE) which provides salary estimates for graduates in different specialties and in different geographical locations. (TW)

  4. Universal Number Library

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lloyd, G. Scott

    This floating-point arithmetic library contains a software implementation of Universal Numbers (unums) as described by John Gustafson [1]. The unum format is a superset of IEEE 754 floating point with several advantages. Computing with unums provides more accurate answers without rounding errors, underflow or overflow. In contrast to fixed-sized IEEE numbers, a variable number of bits can be used to encode unums. This all allows number with only a few significant digits or with a small dynamic range to be represented more compactly.

  5. Implementation of a Fault Tolerant Control Unit within an FPGA for Space Applications

    DTIC Science & Technology

    2006-12-01

    Conference 2002, September 2002. [20] M. Alderighi, A. Candelori, F. Casini, S. D’Angelo, M. Mancini, A. Paccagnella, S. Pastore , G.R. Sechi, “Heavy...Luigi Carro and Ricardo Reis , “Designing and Testing Fault-Tolerant Techniques for SRAM-based FPGAs,” in Proc. 1st Conference on Computer Frontiers, pp...susceptibility,” in IEEE Proc. 12th IEEE Intl. Symposium on On-Line Testing, pp. 89-91, 2006. [45] Fernanda Lima, Luigi Carro and Ricardo Reis

  6. Effect of different adhesive strategies on microtensile bond strength of computer aided design/computer aided manufacturing blocks bonded to dentin.

    PubMed

    Roperto, Renato; Akkus, Anna; Akkus, Ozan; Lang, Lisa; Sousa-Neto, Manoel Damiao; Teich, Sorin; Porto, Thiago Soares

    2016-01-01

    The aim of this study was to determine the microtensile bond strength (μTBS) of ceramic and composite computer aided design-computer aided manufacturing (CAD-CAM) blocks bonded to dentin using different adhesive strategies. In this in vitro study, 30 crowns of sound freshly extracted human molars were sectioned horizontally 3 mm above the cementoenamel junction to produce flat dentin surfaces. Ceramic and composite CAD/CAM blocks, size 14, were sectioned into slices of 3 mm thick. Before bonding, CAD/CAM block surfaces were treated according to the manufacturer's instructions. Groups were created based on the adhesive strategy used: Group 1 (GI) - conventional resin cement + total-etch adhesive system, Group 2 (GII) - conventional resin cement + self-etch adhesive system, and Group 3 (GIII) - self-adhesive resin cement with no adhesive. Bonded specimens were stored in 100% humidity for 24h at 37΀C, and then sectioned with a slow-speed diamond saw to obtain 1 mm × 1 mm × 6 mm microsticks. Microtensile testing was then conducted using a microtensile tester. μTBS values were expressed in MPa and analyzed by one-way ANOVA with post hoc (Tukey) test at the 5% significance level. Mean values and standard deviations of μTBS (MPa) were 17.68 (±2.71) for GI/ceramic; 17.62 (±3.99) for GI/composite; 13.61 (±6.92) for GII/composite; 12.22 (±4.24) for GII/ceramic; 7.47 (±2.29) for GIII/composite; and 6.48 (±3.10) for GIII/ceramic; ANOVA indicated significant differences among the adhesive modality and block interaction (P < 0.05), and no significant differences among blocks only, except between GI and GII/ceramic. Bond strength of GIII was consistently lower (P < 0.05) than GI and GII groups, regardless the block used. Cementation of CAD/CAM restorations, either composite or ceramic, can be significantly affected by different adhesive strategies used.

  7. Software Aspects of IEEE Floating-Point Computations for Numerical Applications in High Energy Physics

    ScienceCinema

    Arnold, Jeffrey

    2018-05-14

    Floating-point computations are at the heart of much of the computing done in high energy physics. The correctness, speed and accuracy of these computations are of paramount importance. The lack of any of these characteristics can mean the difference between new, exciting physics and an embarrassing correction. This talk will examine practical aspects of IEEE 754-2008 floating-point arithmetic as encountered in HEP applications. After describing the basic features of IEEE floating-point arithmetic, the presentation will cover: common hardware implementations (SSE, x87) techniques for improving the accuracy of summation, multiplication and data interchange compiler options for gcc and icc affecting floating-point operations hazards to be avoided. About the speaker: Jeffrey M Arnold is a Senior Software Engineer in the Intel Compiler and Languages group at Intel Corporation. He has been part of the Digital->Compaq->Intel compiler organization for nearly 20 years; part of that time, he worked on both low- and high-level math libraries. Prior to that, he was in the VMS Engineering organization at Digital Equipment Corporation. In the late 1980s, Jeff spent 2½ years at CERN as part of the CERN/Digital Joint Project. In 2008, he returned to CERN to spent 10 weeks working with CERN/openlab. Since that time, he has returned to CERN multiple times to teach at openlab workshops and consult with various LHC experiments. Jeff received his Ph.D. in physics from Case Western Reserve University.

  8. "Reliability Of Fiber Optic Lans"

    NASA Astrophysics Data System (ADS)

    Code n, Michael; Scholl, Frederick; Hatfield, W. Bryan

    1987-02-01

    Fiber optic Local Area Network Systems are being used to interconnect increasing numbers of nodes. These nodes may include office computer peripherals and terminals, PBX switches, process control equipment and sensors, automated machine tools and robots, and military telemetry and communications equipment. The extensive shared base of capital resources in each system requires that the fiber optic LAN meet stringent reliability and maintainability requirements. These requirements are met by proper system design and by suitable manufacturing and quality procedures at all levels of a vertically integrated manufacturing operation. We will describe the reliability and maintainability of Codenoll's passive star based systems. These include LAN systems compatible with Ethernet (IEEE 802.3) and MAP (IEEE 802.4), and software compatible with IBM Token Ring (IEEE 802.5). No single point of failure exists in this system architecture.

  9. Can Humans Fly Action Understanding with Multiple Classes of Actors

    DTIC Science & Technology

    2015-06-08

    recognition using structure from motion point clouds. In European Conference on Computer Vision, 2008. [5] R. Caruana. Multitask learning. Machine Learning...tonomous driving ? the kitti vision benchmark suite. In IEEE Conference on Computer Vision and Pattern Recognition, 2012. [12] L. Gorelick, M. Blank

  10. Deep Learning in Gastrointestinal Endoscopy.

    PubMed

    Patel, Vivek; Armstrong, David; Ganguli, Malika; Roopra, Sandeep; Kantipudi, Neha; Albashir, Siwar; Kamath, Markad V

    2016-01-01

    Gastrointestinal (GI) endoscopy is used to inspect the lumen or interior of the GI tract for several purposes, including, (1) making a clinical diagnosis, in real time, based on the visual appearances; (2) taking targeted tissue samples for subsequent histopathological examination; and (3) in some cases, performing therapeutic interventions targeted at specific lesions. GI endoscopy is therefore predicated on the assumption that the operator-the endoscopist-is able to identify and characterize abnormalities or lesions accurately and reproducibly. However, as in other areas of clinical medicine, such as histopathology and radiology, many studies have documented marked interobserver and intraobserver variability in lesion recognition. Thus, there is a clear need and opportunity for techniques or methodologies that will enhance the quality of lesion recognition and diagnosis and improve the outcomes of GI endoscopy. Deep learning models provide a basis to make better clinical decisions in medical image analysis. Biomedical image segmentation, classification, and registration can be improved with deep learning. Recent evidence suggests that the application of deep learning methods to medical image analysis can contribute significantly to computer-aided diagnosis. Deep learning models are usually considered to be more flexible and provide reliable solutions for image analysis problems compared to conventional computer vision models. The use of fast computers offers the possibility of real-time support that is important for endoscopic diagnosis, which has to be made in real time. Advanced graphics processing units and cloud computing have also favored the use of machine learning, and more particularly, deep learning for patient care. This paper reviews the rapidly evolving literature on the feasibility of applying deep learning algorithms to endoscopic imaging.

  11. GI-13 Integration of Methods for Air Quality and Health Data, Remote Sensed and In-Situ with Disease Estimate Techniques

    EPA Science Inventory

    GI-13 – A brief review of the GEO Work Plan DescriptionGlobal map examples of PM2.5 satellite measuresUS Maps showing examples of fused in-situ and satellite dataNew AQ Monitoring approach with social value – Village Green exampleComputing and Systems Applied in Energ...

  12. Mitigating Spam Using Spatio-Temporal Reputation

    DTIC Science & Technology

    2010-01-01

    scalable; computation can occur in near real-time and over 500,000 emails can be scored an hour. 1 Introduction Roughly 90% of the total volume of email on...Sokolsky, and J. M. Smith. Dynamic trust management. IEEE Computer (Special Issue on Trust Mangement ), 2009. [11] P. Boykins and B. Roychowdhury

  13. Taming Crowded Visual Scenes

    DTIC Science & Technology

    2014-08-12

    Nolan Warner, Mubarak Shah. Tracking in Dense Crowds Using Prominenceand Neighborhood Motion Concurrence, IEEE Transactions on Pattern Analysis...of  computer  vision,   computer   graphics  and  evacuation  dynamics  by  providing  a  common  platform,  and  provides...areas  that  includes  Computer  Vision,  Computer   Graphics ,  and  Pedestrian   Evacuation  Dynamics.  Despite  the

  14. Radiation induced genome instability: multiscale modelling and data analysis

    NASA Astrophysics Data System (ADS)

    Andreev, Sergey; Eidelman, Yuri

    2012-07-01

    Genome instability (GI) is thought to be an important step in cancer induction and progression. Radiation induced GI is usually defined as genome alterations in the progeny of irradiated cells. The aim of this report is to demonstrate an opportunity for integrative analysis of radiation induced GI on the basis of multiscale modelling. Integrative, systems level modelling is necessary to assess different pathways resulting in GI in which a variety of genetic and epigenetic processes are involved. The multilevel modelling includes the Monte Carlo based simulation of several key processes involved in GI: DNA double strand breaks (DSBs) generation in cells initially irradiated as well as in descendants of irradiated cells, damage transmission through mitosis. Taking the cell-cycle-dependent generation of DNA/chromosome breakage into account ensures an advantage in estimating the contribution of different DNA damage response pathways to GI, as to nonhomologous vs homologous recombination repair mechanisms, the role of DSBs at telomeres or interstitial chromosomal sites, etc. The preliminary estimates show that both telomeric and non-telomeric DSB interactions are involved in delayed effects of radiation although differentially for different cell types. The computational experiments provide the data on the wide spectrum of GI endpoints (dicentrics, micronuclei, nonclonal translocations, chromatid exchanges, chromosome fragments) similar to those obtained experimentally for various cell lines under various experimental conditions. The modelling based analysis of experimental data demonstrates that radiation induced GI may be viewed as processes of delayed DSB induction/interaction/transmission being a key for quantification of GI. On the other hand, this conclusion is not sufficient to understand GI as a whole because factors of DNA non-damaging origin can also induce GI. Additionally, new data on induced pluripotent stem cells reveal that GI is acquired in normal mature cells during genome reprogramming by the oncogene c-myc and three additional transcription factors. These and other data reveal the need for generalisation of current model of GI. One can expect that different early events of both DNA damaging and non-damaging origins merge in a single late pathway. To search for a deeper view we propose to redefine GI as genome destabilisation manifested in erosion of genome states and altered transitions between states. This changing view on GI may help to integrate the inducing factors of various origins in the single basic model of GI.

  15. Ontology for cell-based geographic information

    NASA Astrophysics Data System (ADS)

    Zheng, Bin; Huang, Lina; Lu, Xinhai

    2009-10-01

    Inter-operability is a key notion in geographic information science (GIS) for the sharing of geographic information (GI). That requires a seamless translation among different information sources. Ontology is enrolled in GI discovery to settle the semantic conflicts for its natural language appearance and logical hierarchy structure, which are considered to be able to provide better context for both human understanding and machine cognition in describing the location and relationships in the geographic world. However, for the current, most studies on field ontology are deduced from philosophical theme and not applicable for the raster expression in GIS-which is a kind of field-like phenomenon but does not physically coincide to the general concept of philosophical field (mostly comes from the physics concepts). That's why we specifically discuss the cell-based GI ontology in this paper. The discussion starts at the investigation of the physical characteristics of cell-based raster GI. Then, a unified cell-based GI ontology framework for the recognition of the raster objects is introduced, from which a conceptual interface for the connection of the human epistemology and the computer world so called "endurant-occurrant window" is developed for the better raster GI discovery and sharing.

  16. Campus-Wide Computing: Early Results Using Legion at the University of Virginia

    DTIC Science & Technology

    2006-01-01

    Bernard et al., “Primitives for Distributed Computing in a Heterogeneous Local Area Network Environ- ment”, IEEE Trans on Soft. Eng. vol. 15, no. 12...1994. [16] F. Ferstl, “CODINE Technical Overview,” Genias, April, 1993. [17] R. F. Freund and D. S. Cornwell , “Superconcurrency: A form of distributed

  17. Scalable Vector Media-processors for Embedded Systems

    DTIC Science & Technology

    2002-05-01

    Set Architecture for Multimedia “When you do the common things in life in an uncommon way, you will command the attention of the world.” George ...Bibliography [ABHS89] M. August, G. Brost , C. Hsiung, and C. Schiffleger. Cray X-MP: The Birth of a Super- computer. IEEE Computer, 22(1):45–52, January

  18. Securing Emergency State Data in a Tactical Computing Environment

    DTIC Science & Technology

    2010-12-01

    in a Controlled Manner, 19th IEEE Symposium on Computer-Based Medical Systems (CBMS󈧊), 847–854. [38] K. Kifayat, D. Llewellyn - Jones , A. Arabo, O...Drew, M. Merabti, Q. Shi, A. Waller, R. Craddock, G. Jones , State-of-the-Art in System-of-Systems Security for Crisis Management, Fourth Annual

  19. Theoretical Investigation of Optical Computing Based on Neural Network Models.

    DTIC Science & Technology

    1987-09-29

    34 Cognitive and Psychological Computation with Neu- ral Models," IEEE Trans. Sys., Man, and cyber., SMC-13, p. 799, 1983. 20’ K. Nakano, "Association-A...7),482(1986). 211 F. Rosenblatt, Principles of Neurodynamics : Perceptron and the The- ory of Brain Mechanisms, Spartan Books, Washington,(1961). 22

  20. A Placement Test for Computer Science: Design, Implementation, and Analysis

    ERIC Educational Resources Information Center

    Nugent, Gwen; Soh, Leen-Kiat; Samal, Ashok; Lang, Jeff

    2006-01-01

    An introductory CS1 course presents problems for educators and students due to students' diverse background in programming knowledge and exposure. Students who enroll in CS1 also have different expectations and motivations. Prompted by the curricular guidelines for undergraduate programmes in computer science released in 2001 by the ACM/IEEE, and…

  1. An Investigation of Memory Latency Reduction Using an Address Prediction Buffer

    DTIC Science & Technology

    1992-12-01

    McGraw-Hill Inc.. London, England, 1991. [GAJSKI87] Gajski , D.D. et al, Computer Architecture, IEEE Computer Society Press, Washington, D.C., 1987...California, (vol 19 no 3), 1991. [NOWICK92] Nowicki, G ., "Design and Implementation of a Read Prediction Buffer", Master’s Thesis, Naval Postgraduate School

  2. Computer-generated vs. physician-documented history of present illness (HPI): results of a blinded comparison.

    PubMed

    Almario, Christopher V; Chey, William; Kaung, Aung; Whitman, Cynthia; Fuller, Garth; Reid, Mark; Nguyen, Ken; Bolus, Roger; Dennis, Buddy; Encarnacion, Rey; Martinez, Bibiana; Talley, Jennifer; Modi, Rushaba; Agarwal, Nikhil; Lee, Aaron; Kubomoto, Scott; Sharma, Gobind; Bolus, Sally; Chang, Lin; Spiegel, Brennan M R

    2015-01-01

    Healthcare delivery now mandates shorter visits with higher documentation requirements, undermining the patient-provider interaction. To improve clinic visit efficiency, we developed a patient-provider portal that systematically collects patient symptoms using a computer algorithm called Automated Evaluation of Gastrointestinal Symptoms (AEGIS). AEGIS also automatically "translates" the patient report into a full narrative history of present illness (HPI). We aimed to compare the quality of computer-generated vs. physician-documented HPIs. We performed a cross-sectional study with a paired sample design among individuals visiting outpatient adult gastrointestinal (GI) clinics for evaluation of active GI symptoms. Participants first underwent usual care and then subsequently completed AEGIS. Each individual thereby had both a physician-documented and a computer-generated HPI. Forty-eight blinded physicians assessed HPI quality across six domains using 5-point scales: (i) overall impression, (ii) thoroughness, (iii) usefulness, (iv) organization, (v) succinctness, and (vi) comprehensibility. We compared HPI scores within patient using a repeated measures model. Seventy-five patients had both computer-generated and physician-documented HPIs. The mean overall impression score for computer-generated HPIs was higher than physician HPIs (3.68 vs. 2.80; P<0.001), even after adjusting for physician and visit type, location, mode of transcription, and demographics. Computer-generated HPIs were also judged more complete (3.70 vs. 2.73; P<0.001), more useful (3.82 vs. 3.04; P<0.001), better organized (3.66 vs. 2.80; P<0.001), more succinct (3.55 vs. 3.17; P<0.001), and more comprehensible (3.66 vs. 2.97; P<0.001). Computer-generated HPIs were of higher overall quality, better organized, and more succinct, comprehensible, complete, and useful compared with HPIs written by physicians during usual care in GI clinics.

  3. A note on bound constraints handling for the IEEE CEC'05 benchmark function suite.

    PubMed

    Liao, Tianjun; Molina, Daniel; de Oca, Marco A Montes; Stützle, Thomas

    2014-01-01

    The benchmark functions and some of the algorithms proposed for the special session on real parameter optimization of the 2005 IEEE Congress on Evolutionary Computation (CEC'05) have played and still play an important role in the assessment of the state of the art in continuous optimization. In this article, we show that if bound constraints are not enforced for the final reported solutions, state-of-the-art algorithms produce infeasible best candidate solutions for the majority of functions of the IEEE CEC'05 benchmark function suite. This occurs even though the optima of the CEC'05 functions are within the specified bounds. This phenomenon has important implications on algorithm comparisons, and therefore on algorithm designs. This article's goal is to draw the attention of the community to the fact that some authors might have drawn wrong conclusions from experiments using the CEC'05 problems.

  4. The cortical mouse: a piece of forgotten history in noninvasive brain–computer interfaces.

    PubMed

    Principe, Jose C

    2013-07-01

    Early research on brain-computer interfaces (BCIs) was fueled by the study of event-related potentials (ERPs) by Farwell and Donchin, who are rightly credited for laying important groundwork for the BCI field. However, many other researchers have made substantial contributions that have escaped the radar screen of the current BCI community. For example, in the late 1980s, I worked with a brilliant multidisciplinary research group in electrical engineering at the University of Florida, Gainesville, headed by Dr. Donald Childers. Childers should be well known to long-time members of the IEEE Engineering in Medicine and Biology Society since he was the editor-in-chief of IEEE Transactions on Biomedical Engineering in the 1970s and the recipient of one of the most prestigious society awards, the William J. Morlock Award, in 1973.

  5. Blind quantum computing with weak coherent pulses.

    PubMed

    Dunjko, Vedran; Kashefi, Elham; Leverrier, Anthony

    2012-05-18

    The universal blind quantum computation (UBQC) protocol [A. Broadbent, J. Fitzsimons, and E. Kashefi, in Proceedings of the 50th Annual IEEE Symposiumon Foundations of Computer Science (IEEE Computer Society, Los Alamitos, CA, USA, 2009), pp. 517-526.] allows a client to perform quantum computation on a remote server. In an ideal setting, perfect privacy is guaranteed if the client is capable of producing specific, randomly chosen single qubit states. While from a theoretical point of view, this may constitute the lowest possible quantum requirement, from a pragmatic point of view, generation of such states to be sent along long distances can never be achieved perfectly. We introduce the concept of ϵ blindness for UBQC, in analogy to the concept of ϵ security developed for other cryptographic protocols, allowing us to characterize the robustness and security properties of the protocol under possible imperfections. We also present a remote blind single qubit preparation protocol with weak coherent pulses for the client to prepare, in a delegated fashion, quantum states arbitrarily close to perfect random single qubit states. This allows us to efficiently achieve ϵ-blind UBQC for any ϵ>0, even if the channel between the client and the server is arbitrarily lossy.

  6. Blind Quantum Computing with Weak Coherent Pulses

    NASA Astrophysics Data System (ADS)

    Dunjko, Vedran; Kashefi, Elham; Leverrier, Anthony

    2012-05-01

    The universal blind quantum computation (UBQC) protocol [A. Broadbent, J. Fitzsimons, and E. Kashefi, in Proceedings of the 50th Annual IEEE Symposiumon Foundations of Computer Science (IEEE Computer Society, Los Alamitos, CA, USA, 2009), pp. 517-526.] allows a client to perform quantum computation on a remote server. In an ideal setting, perfect privacy is guaranteed if the client is capable of producing specific, randomly chosen single qubit states. While from a theoretical point of view, this may constitute the lowest possible quantum requirement, from a pragmatic point of view, generation of such states to be sent along long distances can never be achieved perfectly. We introduce the concept of ɛ blindness for UBQC, in analogy to the concept of ɛ security developed for other cryptographic protocols, allowing us to characterize the robustness and security properties of the protocol under possible imperfections. We also present a remote blind single qubit preparation protocol with weak coherent pulses for the client to prepare, in a delegated fashion, quantum states arbitrarily close to perfect random single qubit states. This allows us to efficiently achieve ɛ-blind UBQC for any ɛ>0, even if the channel between the client and the server is arbitrarily lossy.

  7. Commentary on the Integration of Model Sharing and Reproducibility Analysis to Scholarly Publishing Workflow in Computational Biomechanics

    PubMed Central

    Erdemir, Ahmet; Guess, Trent M.; Halloran, Jason P.; Modenese, Luca; Reinbolt, Jeffrey A.; Thelen, Darryl G.; Umberger, Brian R.

    2016-01-01

    Objective The overall goal of this document is to demonstrate that dissemination of models and analyses for assessing the reproducibility of simulation results can be incorporated in the scientific review process in biomechanics. Methods As part of a special issue on model sharing and reproducibility in IEEE Transactions on Biomedical Engineering, two manuscripts on computational biomechanics were submitted: A. Rajagopal et al., IEEE Trans. Biomed. Eng., 2016 and A. Schmitz and D. Piovesan, IEEE Trans. Biomed. Eng., 2016. Models used in these studies were shared with the scientific reviewers and the public. In addition to the standard review of the manuscripts, the reviewers downloaded the models and performed simulations that reproduced results reported in the studies. Results There was general agreement between simulation results of the authors and those of the reviewers. Discrepancies were resolved during the necessary revisions. The manuscripts and instructions for download and simulation were updated in response to the reviewers’ feedback; changes that may otherwise have been missed if explicit model sharing and simulation reproducibility analysis were not conducted in the review process. Increased burden on the authors and the reviewers, to facilitate model sharing and to repeat simulations, were noted. Conclusion When the authors of computational biomechanics studies provide access to models and data, the scientific reviewers can download and thoroughly explore the model, perform simulations, and evaluate simulation reproducibility beyond the traditional manuscript-only review process. Significance Model sharing and reproducibility analysis in scholarly publishing will result in a more rigorous review process, which will enhance the quality of modeling and simulation studies and inform future users of computational models. PMID:28072567

  8. Modality-Driven Classification and Visualization of Ensemble Variance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bensema, Kevin; Gosink, Luke; Obermaier, Harald

    Paper for the IEEE Visualization Conference Advances in computational power now enable domain scientists to address conceptual and parametric uncertainty by running simulations multiple times in order to sufficiently sample the uncertain input space.

  9. The RISC (Reduced Instruction Set Computer) Architecture and Computer Performance Evaluation.

    DTIC Science & Technology

    1986-03-01

    time where the main emphasis of the evaluation process is put on the software . The model is intended to provide a tool for computer architects to use...program, or 3) Was to be implemented in random logic more effec- tively than the equivalent sequence of software instructions. Both data and address...definition is the IEEE standard 729-1983 stating Computer Architecture as: " The process of defining a collection of hardware and software components and

  10. Organizing the History of Computing

    NASA Astrophysics Data System (ADS)

    Misa, Thomas J.

    This paper tries to distill some of the ‘lessons learned’ from the Charles Babbage Institute’s quarter-century experience (1980-present) in organizing the history of computing. It draws on the author’s (recent) experience as CBI director; conversations with Arthur Norberg, CBI’s long-time founding director; and papers delivered at a special symposium appraising CBI’s role in computing history, which appeared in the IEEE Annals of the History of Computing 29 no. 4 (October-December 2007).

  11. Socially Relevant Knowledge Based Telemedicine

    DTIC Science & Technology

    2011-10-01

    or attitude at different situations and different circumstances. Fogg mentions that there are many reasons that computers can be better persuaders...finding appropriate way to persuade users to perform various activities. Fogg [8] defines persuasive technologies as “interactive computing systems...Education, IEEE Consumer Electronics Society Conference Games Innovation, ICE-GIC, 2009, pp 54-63. [8] Fogg , B. J., Persuasive Technology: Using

  12. Primary aortoduodenal fistula associated with abdominal aortic aneurysm with presentation of gastrointestinal bleeding: a case report.

    PubMed

    Lin, Tzu-Chieh; Tsai, Chung-Lin; Chang, Yao-Tien; Hu, Sung-Yuan

    2018-06-07

    Primary aortoduodenal fistula (ADF) is a rare cause of gastrointestinal (GI) bleeding and is difficult to diagnose as the clinical presentation is subtle. Clinicians should keep a high level of suspicion for an unknown etiology of GI bleeding, especially in older patients with or without abdominal aortic aneurysm (AAA). Computed tomographic angiography (CTA) can be used to detect primary ADF. Open surgery or endovascular aortic repair (EVAR) for ADF with bleeding will improve the survival rate. We report a rare case of AAA complicating ADF with massive GI bleeding in a 73-year-old Taiwanese man. He presented with abdominal pain and tarry stool for 5 days and an initial upper GI endoscopy at a rural hospital showed gastric ulcer only, but hypotension with tachycardia and a drop in hemoglobin of 9 g/dl from 12 g/dl occurred the next day. He was referred to our hospital for EVAR and primary closure of fistula defect due to massive GI bleeding with shock from ADF caused by AAA. Diagnosis was made by CTA of aorta. A timely and accurate diagnosis of primary ADF may be challenging due to insidious episodes of GI bleeding, which are frequently under-diagnosed until the occurrence of massive hemorrhage. Clinical physicians should keep a high index of awareness for primary ADF, especially in elderly patients with unknown etiology of upper GI bleeding with or without a known AAA.

  13. The Future of Mobile Information and Communication Technology in Austere Environments: A Command and Control Technology Integration Perspective

    DTIC Science & Technology

    2013-03-01

    within the Global information Grid ( GiG ) (AFDD6-0, 2011). JP 1-02 describes the GiG : 10 The GIG is the globally interconnected, end-to-end set of...to warfighters, policy makers, and support personnel. The GIG includes all owned and leased communications and computing systems and services...software (including applications), data, security services, and other 19 associated services necessary to achieve information superiority. The GIG

  14. A 1998 Workshop on Heterogeneous Computing

    DTIC Science & Technology

    1998-09-18

    of Sussex, England, in 1994. From 1988 to 1990 he was a Lecturer with the UNAM. In 1994, he joined the Laboratorio Nacional de Informatica Avanzada...1984) and at the UNAM (1988-1991). Since 1992, he is titular Researcher and consultant at the Laboratorio Nacional de Informatica Avanzada (LANIA). He...Box 1331 Piscataway, NJ 08855-1331 Tel: + 1-908-981-1393 Fax: + 1-908-981-9667 mis.custserv@computer.org IEEE Computer Society 13, Avenue de

  15. TomoBank: a tomographic data repository for computational x-ray science

    NASA Astrophysics Data System (ADS)

    De Carlo, Francesco; Gürsoy, Doğa; Ching, Daniel J.; Joost Batenburg, K.; Ludwig, Wolfgang; Mancini, Lucia; Marone, Federica; Mokso, Rajmund; Pelt, Daniël M.; Sijbers, Jan; Rivers, Mark

    2018-03-01

    There is a widening gap between the fast advancement of computational methods for tomographic reconstruction and their successful implementation in production software at various synchrotron facilities. This is due in part to the lack of readily available instrument datasets and phantoms representative of real materials for validation and comparison of new numerical methods. Recent advancements in detector technology have made sub-second and multi-energy tomographic data collection possible (Gibbs et al 2015 Sci. Rep. 5 11824), but have also increased the demand to develop new reconstruction methods able to handle in situ (Pelt and Batenburg 2013 IEEE Trans. Image Process. 22 5238-51) and dynamic systems (Mohan et al 2015 IEEE Trans. Comput. Imaging 1 96-111) that can be quickly incorporated in beamline production software (Gürsoy et al 2014 J. Synchrotron Radiat. 21 1188-93). The x-ray tomography data bank, tomoBank, provides a repository of experimental and simulated datasets with the aim to foster collaboration among computational scientists, beamline scientists, and experimentalists and to accelerate the development and implementation of tomographic reconstruction methods for synchrotron facility production software by providing easy access to challenging datasets and their descriptors.

  16. Role of enhanced multi-detector-row computed tomography before urgent endoscopy in acute upper gastrointestinal bleeding.

    PubMed

    Miyaoka, Youichi; Amano, Yuji; Ueno, Sayaka; Izumi, Daisuke; Mikami, Hironobu; Yazaki, Tomotaka; Okimoto, Eiko; Sonoyama, Takayuki; Ito, Satoko; Fujishiro, Hirofumi; Kohge, Naruaki; Imaoka, Tomonori

    2014-04-01

    Multi-detector-row computed tomography (MDCT) has been reported to be a potentially useful modality for detection of the bleeding origin in patients with acute upper massive gastrointestinal (GI) bleeding. The purpose of this study is to investigate the efficacy of MDCT as a routine method for detecting the origin of acute upper GI bleeding prior to urgent endoscopy. Five hundred seventy-seven patients with acute upper GI bleeding (514 nonvariceal patients, 63 variceal patients) who underwent urgent upper GI endoscopy were retrospectively analyzed. Patients were divided into three groups: enhanced MDCT, unenhanced MDCT, and no MDCT before endoscopy. The diagnostic accuracy of MDCT for detection of the bleeding origin was evaluated, and the average procedure times needed to endoscopically identify the bleeding origin were compared between groups. Diagnostic accuracy among endoscopists was 55.3% and 14.7% for the enhanced MDCT and unenhanced MDCT groups, respectively. Among nonvariceal patients, accuracy was 50.2% in the enhanced MDCT group, which was significantly better than that in the unenhanced MDCT group (16.5%). In variceal patients, accuracy was significantly better in the enhanced MDCT group (96.4%) than in the unenhanced MDCT group (0.0%). These accuracies were similar to those achieved by expert radiologists. The average procedure time to endoscopic detection of the bleeding origin in the enhanced MDCT group was significantly faster than that in the unenhanced MDCT and no-MDCT groups. Enhanced MDCT preceding urgent endoscopy may be an effective modality for the detection of bleeding origin in patients with acute upper GI bleeding. © 2013 Journal of Gastroenterology and Hepatology Foundation and Wiley Publishing Asia Pty Ltd.

  17. Deployment of Directory Service for IEEE N Bus Test System Information

    NASA Astrophysics Data System (ADS)

    Barman, Amal; Sil, Jaya

    2008-10-01

    Exchanging information over Internet and Intranet becomes a defacto standard in computer applications, among various users and organizations. Distributed system study, e-governance etc require transparent information exchange between applications, constituencies, manufacturers, and vendors. To serve these purposes database system is needed for storing system data and other relevant information. Directory service, which is a specialized database along with access protocol, could be the single solution since it runs over TCP/IP, supported by all POSIX compliance platforms and is based on open standard. This paper describes a way to deploy directory service, to store IEEE n bus test system data and integrating load flow program with it.

  18. Advanced Materials for Quantum Computing

    DTIC Science & Technology

    2010-04-28

    with Magnons co-PI: Leszek Malkinski w/ Postdoc Dr. Seong-Gi Min Project Name: Quantum Computing with Magnons 1. Brief Narrative: Quanta of...spinwaves called magnons can be used to exchange quantum information between solid state qubits. The project was driven by the concept of spiwave bus

  19. Laparoscopic and ultrasound assisted management of gallstone ileus after biliointestinal bypass Case report and a review of literature.

    PubMed

    Zago, Mauro; Bozzo, Samantha; Centurelli, Andrea; Giovanelli, Alessandro; Vasino, Michele Ciocca

    2016-05-24

    To report about an additional case of biliary ileus after bariatric surgery is reported and extensively reviewing the literature on this topic. We reviewed the literature and found three cases of gallstone ileus (GI) that occurred after bariatric surgery. A 41 year old patient presented a GI eight years after a biliointestinal bypass (BIB) for morbid obesity. The patient complained of abdominal pain for two weeks. Computed tomography (CT) and abdominal ultrasound (US) allowed a preoperative diagnosis of GI and planning of surgical strategy. Surgical treatment was carried out through laparoscopic-assisted enterolithotomy alone procedure. This choice is supported discussing the related issues: morbidity, potential recurrence, eventual developing of gallbladder carcinoma. It is the first reported case of GI after BIB preoperatively diagnosed through CT scan and US, and treated with a laparoscopic assisted approach. Additional considerations concerning preoperative diagnosis, surgical strategy, technical details and follow-up can be usefully applied even in non post-bariatric biliary ileus. Biliointestinal bypass, Gallstone ileus, Laparoscopy, Ultrasonography.

  20. Enhancing the Selection of Backoff Interval Using Fuzzy Logic over Wireless Ad Hoc Networks

    PubMed Central

    Ranganathan, Radha; Kannan, Kathiravan

    2015-01-01

    IEEE 802.11 is the de facto standard for medium access over wireless ad hoc network. The collision avoidance mechanism (i.e., random binary exponential backoff—BEB) of IEEE 802.11 DCF (distributed coordination function) is inefficient and unfair especially under heavy load. In the literature, many algorithms have been proposed to tune the contention window (CW) size. However, these algorithms make every node select its backoff interval between [0, CW] in a random and uniform manner. This randomness is incorporated to avoid collisions among the nodes. But this random backoff interval can change the optimal order and frequency of channel access among competing nodes which results in unfairness and increased delay. In this paper, we propose an algorithm that schedules the medium access in a fair and effective manner. This algorithm enhances IEEE 802.11 DCF with additional level of contention resolution that prioritizes the contending nodes according to its queue length and waiting time. Each node computes its unique backoff interval using fuzzy logic based on the input parameters collected from contending nodes through overhearing. We evaluate our algorithm against IEEE 802.11, GDCF (gentle distributed coordination function) protocols using ns-2.35 simulator and show that our algorithm achieves good performance. PMID:25879066

  1. Compliance and Functional Testing of IEEE 1451.1 for NCAP-to-NCAP Communications in a Sensor Network

    NASA Technical Reports Server (NTRS)

    Figueroa, Jorge; Gurkan, Deniz; Yuan, X.; Benhaddou, D.; Liu, H.; Singla, A.; Franzl, R.; Ma, H.; Bhatt, S.; Morris, J.; hide

    2008-01-01

    Distributed control in a networked environment is an irreplaceable feature in systems with remote sensors and actuators. Although distributed control was not originally designed to be networked, usage of off-the-shelf networking technologies has become so prevalent that control systems are desired to have access mechanisms similar to computer networks. However, proprietary transducer interfaces for network communications and distributed control overwhelmingly dominate this industry. Unless the lack of compatibility and interoperability among transducers is resolved, the mature level of access (that computer networking can deliver) will not be achieved in such networked distributed control systems. Standardization of networked transducer interfaces will enable devices from different manufacturers to talk to each other and ensure their plug-and-play capability. One such standard is the suite of IEEE 1451 for sensor network communication and transducer interfaces. The suite not only provides a standard interface for smart transducers, but also outlines the connection of an NCAP (network capable application processor) and transducers (through a transducer interface module TIM). This paper presents the design of the compliance testing of IEEE 1451.1 (referred to as Dot1) compatible NCAP-to-NCAP communications on a link-layer independent medium. The paper also represents the first demonstration of NCAP-to-NCAP communications with Dot1 compatibility: a tester NCAP and an NCAP under test (NUT).

  2. Computational estimation of magnetically induced electric fields in a rotating head

    NASA Astrophysics Data System (ADS)

    Ilvonen, Sami; Laakso, Ilkka

    2009-01-01

    Change in a magnetic field, or similarly, movement in a strong static magnetic field induces electric fields in human tissues, which could potentially cause harmful effects. In this paper, the fields induced by different rotational movements of a head in a strong homogeneous magnetic field are computed numerically. Average field magnitudes near the retinas and inner ears are studied in order to gain insight into the causes of phosphenes and vertigo-like effects, which are associated with extremely low-frequency (ELF) magnetic fields. The induced electric fields are calculated in four different anatomically realistic head models using an efficient finite-element method (FEM) solver. The results are compared with basic restriction limits by IEEE and ICNIRP. Under rotational movement of the head, with a magnetic flux rate of change of 1 T s-1, the maximum IEEE-averaged electric field and maximum ICNIRP-averaged current density were 337 mV m-1 and 8.84 mA m-2, respectively. The limits by IEEE seem significantly stricter than those by ICNIRP. The results show that a magnetic flux rate of change of 1 T s-1 may induce electric field in the range of 50 mV m-1 near retinas, and possibly even larger values near the inner ears. These results provide information for approximating the threshold electric field values of phosphenes and vertigo-like effects.

  3. Passive Localization of Multiple Sources Using Widely-Spaced Arrays With Application to Marine Mammals

    DTIC Science & Technology

    2006-09-30

    IEEE OES Student Poster Program Oceans ’05 Europe, Brest, France, June 20-23, 2005. Sponsored by Thales Underwater Systems. Student Engagement Award to E.-M. Nosal – Maui High Performance Computing Center (2005-2006).

  4. FloCon 2011 Proceedings

    DTIC Science & Technology

    2011-01-01

    and G. Armitage. Dening and evaluating greynets (sparse darknets ). In LCN󈧉: Proceedings of the IEEE Conference on Local Computer Networks 30th...analysis of distributed darknet trac. In IMC󈧉: Proceedings of the USENIX/ACM Internet Measurement Conference, 2005. Indexing Full Packet Capture Data

  5. IEEE TRANSACTIONS ON CYBERNETICS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Craig R. RIeger; David H. Scheidt; William D. Smart

    2014-11-01

    MODERN societies depend on complex and critical infrastructures for energy, transportation, sustenance, medical care, emergency response, communications security. As computers, automation, and information technology (IT) have advanced, these technologies have been exploited to enhance the efficiency of operating the processes that make up these infrastructures

  6. An IEEE 1451.1 Architecture for ISHM Applications

    NASA Technical Reports Server (NTRS)

    Morris, Jon A.; Turowski, Mark; Schmalzel, John L.; Figueroa, Jorge F.

    2007-01-01

    The IEEE 1451.1 Standard for a Smart Transducer Interface defines a common network information model for connecting and managing smart elements in control and data acquisition networks using network-capable application processors (NCAPs). The Standard is a network-neutral design model that is easily ported across operating systems and physical networks for implementing complex acquisition and control applications by simply plugging in the appropriate network level drivers. To simplify configuration and tracking of transducer and actuator details, the family of 1451 standards defines a Transducer Electronic Data Sheet (TEDS) that is associated with each physical element. The TEDS contains all of the pertinent information about the physical operations of a transducer (such as operating regions, calibration tables, and manufacturer information), which the NCAP uses to configure the system to support a specific transducer. The Integrated Systems Health Management (ISHM) group at NASA's John C. Stennis Space Center (SSC) has been developing an ISHM architecture that utilizes IEEE 1451.1 as the primary configuration and data acquisition mechanism for managing and collecting information from a network of distributed intelligent sensing elements. This work has involved collaboration with other NASA centers, universities and aerospace industries to develop IEEE 1451.1 compliant sensors and interfaces tailored to support health assessment of complex systems. This paper and presentation describe the development and implementation of an interface for the configuration, management and communication of data, information and knowledge generated by a distributed system of IEEE 1451.1 intelligent elements monitoring a rocket engine test system. In this context, an intelligent element is defined as one incorporating support for the IEEE 1451.x standards and additional ISHM functions. Our implementation supports real-time collection of both measurement data (raw ADC counts and converted engineering units) and health statistics produced by each intelligent element. The handling of configuration, calibration and health information is automated by using the TEDS in combination with other electronic data sheets extensions to convey health parameters. By integrating the IEEE 1451.1 Standard for a Smart Transducer Interface with ISHM technologies, each element within a complex system becomes a highly flexible computation engine capable of self-validation and performing other measures of the quality of information it is producing.

  7. MCloud: Secure Provenance for Mobile Cloud Users

    DTIC Science & Technology

    2016-10-03

    Feasibility of Smartphone Clouds , 2015 15th IEEE/ACM International Symposium on Cluster, Cloud and Grid Computing (CCGrid). 04-MAY- 15, Shenzhen, China...final decision. MCloud: Secure Provenance for Mobile Cloud Users Final Report Bogdan Carbunar Florida International University Computing and...Release; Distribution Unlimited UU UU UU UU 03-10-2016 31-May-2013 30-May-2016 Final Report: MCloud: Secure Provenance for Mobile Cloud Users The views

  8. Probabilistic QoS Analysis In Wireless Sensor Networks

    DTIC Science & Technology

    2012-04-01

    and A.O. Fapojuwo. TDMA scheduling with optimized energy efficiency and minimum delay in clustered wireless sensor networks . IEEE Trans. on Mobile...Research Computer Science and Engineering, Department of 5-1-2012 Probabilistic QoS Analysis in Wireless Sensor Networks Yunbo Wang University of...Wang, Yunbo, "Probabilistic QoS Analysis in Wireless Sensor Networks " (2012). Computer Science and Engineering: Theses, Dissertations, and Student

  9. Investigation of Current State of Crytpography and Theoretical Implementation of a Cryptographic System for the Combat Service Support Control System.

    DTIC Science & Technology

    1987-05-01

    34 Advances in Crypt g: Proceedings of CRYPTO 84,r o ... .. .. _ __...o ... .. ... ....... ed. by G.R. Blakely and D. Chaum . [Wagn84b] Wagner, Neal R...in Distributed Computer Systems," IEEE Trans. on Computers, Vol. C-35, No. 7, Jul. 86, pp. 583-590. Gifford, David K., "Cryptographic Sealing for

  10. Natural Tasking of Robots Based on Human Interaction Cues

    DTIC Science & Technology

    2005-06-01

    MIT. • Matthew Marjanovic , researcher, ITA Software. • Brian Scasselatti, Assistant Professor of Computer Science, Yale. • Matthew Williamson...2004. 25 [74] Charlie C. Kemp. Shoes as a platform for vision. 7th IEEE International Symposium on Wearable Computers, 2004. [75] Matthew Marjanovic ...meso: Simulated muscles for a humanoid robot. Presentation for Humanoid Robotics Group, MIT AI Lab, August 2001. [76] Matthew J. Marjanovic . Teaching

  11. Training in software used by practising engineers should be included in university curricula

    NASA Astrophysics Data System (ADS)

    Silveira, A.; Perdigones, A.; García, J. L.

    2009-04-01

    Deally, an engineering education should prepare students, i.e., emerging engineers, to use problem-solving processes that synergistically combine creativity and imagination with rigour and discipline. Recently, pressures on curricula have resulted in the development of software-specific courses, often to the detriment of the understanding of theory [1]. However, it is also true that there is a demand for information technology courses by students other than computer science majors [2]. The emphasis on training engineers may be best placed on answering the needs of industry; indeed, many proposals are now being made to try to reduce the gap between the educational and industrial communities [3]. Training in the use of certain computer programs may be one way of better preparing engineering undergraduates for eventual employment in industry. However, industry's needs in this respect must first be known. The aim of this work was to determine which computer programs are used by practising agricultural engineers with the aim of incorporating training in their use into our department's teaching curriculum. The results showed that 72% of their working hours involved the use computer programs. The software packages most commonly used were Microsoft Office (used by 79% of respondents) and CAD (56%), as well as budgeting (27%), statistical (21%), engineering (15%) and GIS (13%) programs. As a result of this survey our university department opened an additional computer suite in order to provide students practical experience in the use of Microsoft Excel, budgeting and engineering software. The results of this survey underline the importance of computer software training in this and perhaps other fields of engineering. [1] D. J. Moore, and D. R. Voltmer, "Curriculum for an engineering renaissance," IEEE Trans. Educ., vol. 46, pp. 452-455, Nov. 2003. [2] N. Kock, R. Aiken, and C. Sandas, "Using complex IT in specific domains: developing and assessing a course for nonmajors," IEEE Trans. Educ., vol. 45, pp. 50- 56, Feb. 2002. [3] I. Vélez, and J. F. Sevillano, "A course to train digital hardware designers for industry," IEEE Trans. Educ., vol. 50, pp. 236-243, Aug. 2007. Acknowledgement: This work was supported in part by the Universidad Politécnica de Madrid, Spain.

  12. Message From the Editor for Contributions to the 2010 Real Time Conference Issue of TNS

    NASA Astrophysics Data System (ADS)

    Schmeling, Sascha Marc

    2011-08-01

    The 72 papers in this special issue were originally presented at the 17th IEEE-NPSS Real Time Conference (RT2010) on Computing Applications in Nuclear and Plasma Sciences, held in Lisbon, Portugal in May 2010.

  13. Proof Search in an Authorization Logic

    DTIC Science & Technology

    2009-04-14

    and Itay Neeman. DKAL: Distributed-knowledge authorization language. In Proceedings of the 21st IEEE Symposium on Computer Security Foundations (CSF...21), 2008. [33] Yuri Gurevich and Itay Neeman. The logic of infons. Technical report, Microsoft Research, 2009. [34] Joshua S. Hodas and Dale Miller

  14. Making Classical Ground State Spin Computing Fault-Tolerant

    DTIC Science & Technology

    2010-06-24

    approaches to perebor (brute-force searches) algorithms,” IEEE Annals of the History of Computing, 6, 384–400 (1984). [24] D. Bacon and S . T. Flammia ...Adiabatic gate teleportation,” Phys. Rev. Lett., 103, 120504 (2009). [25] D. Bacon and S . T. Flammia , “Adiabatic cluster state quantum computing...v1 [ co nd -m at . s ta t- m ec h] 2 2 Ju n 20 10 Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the

  15. A Unified Framework for Simulating Markovian Models of Highly Dependable Systems

    DTIC Science & Technology

    1989-07-01

    ependability I’valuiation of Complex lault- lolerant Computing Systems. Ptreedings of the 1-.et-enth Sv~npmiun on Falult- lolerant Comnputing. Portland, Maine...New York. [12] (icis;t, R.M. and ’I’rivedi, K.S. (1983). I!Itra-Il gh Reliability Prediction for Fault-’ lolerant Computer Systems. IEE.-E Trw.%,.cions... 1998 ). Surv’ey of Software Tools for [valuating Reli- ability. A vailability, and Serviceabilitv. ACA1 Computing S urveyjs 20. 4, 227-269). [32] Meyer

  16. Communication-Efficient Arbitration Models for Low-Resolution Data Flow Computing

    DTIC Science & Technology

    1988-12-01

    phase can be formally described as follows: Graph Partitioning Problem NP-complete: (Garey & Johnson) Given graph G = (V, E), weights w (v) for each v e V...Technical Report, MIT/LCS/TR-218, Cambridge, Mass. Agerwala, Tilak, February 1982, "Data Flow Systems", Computer, pp. 10-13. Babb, Robert G ., July 1984...34Parallel Processing with Large-Grain Data Flow Techniques," IEEE Computer 17, 7, pp. 55-61. Babb, Robert G ., II, Lise Storc, and William C. Ragsdale

  17. An Unusual Clinical Presentation of Gastrointestinal Metastasis From Invasive Lobular Carcinoma of Breast.

    PubMed

    Balakrishnan, Bathmapriya; Shaik, Sufiya; Burman-Solovyeva, Irina

    2016-01-01

    Introduction. We present an unusual case of metastatic lobular breast carcinoma. Typical areas of metastasis include bone, gynecological organs, peritoneum, retroperitoneum, and gastrointestinal (GI) tract, in order of frequency. With regard to GI metastasis, extrahepatic represents a rare site. Case. Two years after being diagnosed with invasive lobular breast carcinoma, a 61-year-old female complained of 3 months of nonspecific abdominal pain and diarrhea. A colonoscopy revealed 5 tubular adenomatous polyps in the ascending and transverse colon. Contrast computed tomography (CT) of the abdomen and pelvis was done 7 months after the colonoscopy to further evaluate persistent diarrhea. The CT results were consistent with infectious or inflammatory enterocolitis. Despite conservative management, symptoms failed to improve and a repeat diagnostic colonoscopy was obtained. Random colonic biopsies revealed metastatic high-grade adenocarcinoma of the colon. Discussion. Metastatic lobular breast carcinoma to the GI tract can distort initial interpretation of endoscopic evaluation with lesions mimicking inflammation. The interval between discovery of GI metastasis and diagnosis of lobular breast cancer can vary widely from synchronous to 30 years; however, progression is most often much sooner. Nonspecific symptoms and subtle appearance of metastatic lesions may confound the diagnosis. A high index of suspicion is needed for possible metastatic spread to the GI tract in patients with a history of invasive lobular breast carcinoma. Perhaps, patients with nonspecific GI symptoms should have an endoscopic examination with multiple random biopsies as invasive lobular carcinoma typically mimics macroscopic changes consistent with colitis.

  18. Bio-Inspired Navigation of Chemical Plumes

    DTIC Science & Technology

    2006-07-01

    Bio-Inspired Navigation of Chemical Plumes Maynard J. Porter III, Captain, USAF Department of Electrical and Computer Engineering Air Force Institute...Li. " Chemical plume tracing via an autonomous underwater vehicle". IEEE Journal of Ocean Engineering , 30(2):428— 442, 2005. [6] G. A. Nevitt...Electrical and Computer Engineering Air Force Institute of Technology Dayton, OH 45433-7765, U.S.A. juan.vasquez@afit.edu May 31, 2006 Abstract - The

  19. Tunable Optical Sources.

    DTIC Science & Technology

    1980-11-01

    finite aperture size 5. A. E. Siegman , "Unstable optical resonators for laser of the YAG rod, applications," Proc. IEEE 53, 217-287 (1965); "Unstable...Pumped LiNbO3 Tunable Source Radial Birefringent Element Computer Controlled Laser Attenuator Slab Configuration Laser Source 20. ABSTRACT (Continue on...have invented and demonstrated a computer controlled laser attenu- ator. .... Cont inued DD Il 7 1473 EDITION OF I NOV 01 IS OBSOLETE UNCLASSIFIEDAN

  20. QCDOC: A 10-teraflops scale computer for lattice QCD

    NASA Astrophysics Data System (ADS)

    Chen, D.; Christ, N. H.; Cristian, C.; Dong, Z.; Gara, A.; Garg, K.; Joo, B.; Kim, C.; Levkova, L.; Liao, X.; Mawhinney, R. D.; Ohta, S.; Wettig, T.

    2001-03-01

    The architecture of a new class of computers, optimized for lattice QCD calculations, is described. An individual node is based on a single integrated circuit containing a PowerPC 32-bit integer processor with a 1 Gflops 64-bit IEEE floating point unit, 4 Mbyte of memory, 8 Gbit/sec nearest-neighbor communications and additional control and diagnostic circuitry. The machine's name, QCDOC, derives from "QCD On a Chip".

  1. Hybrid Architectures for Evolutionary Computing Algorithms

    DTIC Science & Technology

    2008-01-01

    other EC algorithms to FPGA Core Burns P1026/MAPLD 200532 Genetic Algorithm Hardware References S. Scott, A. Samal , and S. Seth, “HGA: A Hardware Based...on Parallel and Distributed Processing (IPPS/SPDP 󈨦), pp. 316-320, Proceedings. IEEE Computer Society 1998. [12] Scott, S. D. , Samal , A., and...Algorithm Hardware References S. Scott, A. Samal , and S. Seth, “HGA: A Hardware Based Genetic Algorithm”, Proceedings of the 1995 ACM Third

  2. Development of Computational Simulation Tools to Model Weapon Propulsors

    DTIC Science & Technology

    2004-01-01

    Calculation in Permanent Magnet Motors with Rotor Eccentricity: With Slotting Effect Considered," IEEE Transactions on Magnetics, Volume 34, No. 4, 2253-2266...1998). [3] Lieu, Dennis K., Kim, Ungtae. "Magnetic Field Calculation in Permanent Magnet Motors with Rotor Eccentricity: Without Slotting Effect

  3. Database Translator (DATALATOR) for Integrated Exploitation

    DTIC Science & Technology

    2010-10-31

    Modelling in Information Systems Engineering. 2007, Berlin : Springer, pp. 39-58. 2. Arnon Rosenthal, Len Seligman . Pragmatics and Open Problems for Inter...2004, Vol. 2938 . 21. Ahuja, S., N. Carriero and D. Gelemte,. Linda and friends. IEEE Computer. August 1986, pp. 26- 32. 40 Next Generation Software

  4. Baiting Inside Attackers using Decoy Documents

    DTIC Science & Technology

    2008-09-16

    viewed. Animated images allow the senders to monitor how long the message was displayed. The web bugs operate without alerting the user of the...Military Computer Security Policies”. IEEE Symposium on Security and Privacy, 1987. [5] Demers, A., Gehrke, J., Hong, M., Panda , B., Riedewald, M., Sharma

  5. Joint Services Electronics Program

    DTIC Science & Technology

    1991-03-05

    Parallel Computing Network and Program Professor Abhiram Ranade with M.T. Raghunath and Robert Boothe The goal of our research is to develop high...References/Publications [1] M. T. Raghunath and A. 0. Ranade. "A Simulation-Based Comparison of Interconnection Networks," Proceedings of the 2nd IEEE

  6. Local Area Networks: Part I.

    ERIC Educational Resources Information Center

    Dessy, Raymond E.

    1982-01-01

    Local area networks are common communication conduits allowing various terminals, computers, discs, printers, and other electronic devices to intercommunicate over short distances. Discusses the vocabulary of such networks including RS-232C point-to-point and IEEE-488 multidrop protocols; error detection; message packets; multiplexing; star, ring,…

  7. Message From the Editor for Contributions to the 2007 Real Time Conference Issue of TNS

    NASA Astrophysics Data System (ADS)

    Dufey, Jean-Pierre

    2008-02-01

    This issue presents 67 papers which were originally presented at the 15th IEEE-NPSS Real Time Conference (RT2007) on Computing Applications in Nuclear and Plasma Sciences held at Fermilab, Batavia, IL, April 29-May 4, 2007.

  8. Assessing Cost-effectiveness of Green Infrastructures in response to Large Storm Events at Household Scale

    NASA Astrophysics Data System (ADS)

    Chui, T. F. M.; Liu, X.; Zhan, W.

    2015-12-01

    Green infrastructures (GI) are becoming more important for urban stormwater control worldwide. However, relatively few studies focus on researching the specific designs of GI at household scale. This study assesses the hydrological performance and cost-effectiveness of different GI designs, namely green roofs, bioretention systems and porous pavements. It aims to generate generic insights by comparing the optimal designs of each GI in 2-year and 50-year storms of Hong Kong, China and Seattle, US. EPA SWMM is first used to simulate the hydrologic performance, in particular, the peak runoff reduction of thousands of GI designs. Then, life cycle costs of the designs are computed and their effectiveness, in terms of peak runoff reduction percentage per thousand dollars, is compared. The peak runoff reduction increases almost linearly with costs for green roofs. However, for bioretention systems and porous pavements, peak runoff reduction only increases significantly with costs in the mid values. For achieving the same peak runoff reduction percentage, the optimal soil depth of green roofs increases with the design storm, while surface area does not change significantly. On the other hand, for bioretention systems and porous pavements, the optimal surface area increases with the design storm, while thickness does not change significantly. In general, the cost effectiveness of porous pavements is highest, followed by bioretention systems and then green roofs. The cost effectiveness is higher for a smaller storm, and is thus higher for 2-year storm than 50-year storm, and is also higher for Seattle when compared to Hong Kong. This study allows us to better understand the hydrological performance and cost-effectiveness of different GI designs. It facilitates the implementation of optimal choice and design of each specific GI for stormwater mitigation.

  9. IEEE Smart Grid Series of Standards IEEE 2030 (Interoperability) and IEEE 1547 (Interconnection) Status: Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Basso, T.; DeBlasio, R.

    The IEEE American National Standards smart grid publications and standards development projects IEEE 2030, which addresses smart grid interoperability, and IEEE 1547TM, which addresses distributed resources interconnection with the grid, have made substantial progress since 2009. The IEEE 2030TM and 1547 standards series focus on systems-level aspects and cover many of the technical integration issues involved in a mature smart grid. The status and highlights of these two IEEE series of standards, which are sponsored by IEEE Standards Coordinating Committee 21 (SCC21), are provided in this paper.

  10. Application of PSAT to Load Flow Analysis with STATCOM under Load Increase Scenario and Line Contingencies

    NASA Astrophysics Data System (ADS)

    Telang, Aparna S.; Bedekar, P. P.

    2017-09-01

    Load flow analysis is the initial and essential step for any power system computation. It is required for choosing better options for power system expansion to meet with ever increasing load demand. Implementation of Flexible AC Transmission System (FACTS) device like STATCOM, in the load flow, which is having fast and very flexible control, is one of the important tasks for power system researchers. This paper presents a simple and systematic approach for steady state power flow calculations with FACTS controller, static synchronous compensator (STATCOM) using command line usage of MATLAB tool-power system analysis toolbox (PSAT). The complexity of MATLAB language programming increases due to incorporation of STATCOM in an existing Newton-Raphson load flow algorithm. Thus, the main contribution of this paper is to show how command line usage of user friendly MATLAB tool, PSAT, can extensively be used for quicker and wider interpretation of the results of load flow with STATCOM. The novelty of this paper lies in the method of applying the load increase pattern, where the active and reactive loads have been changed simultaneously at all the load buses under consideration for creating stressed conditions for load flow analysis with STATCOM. The performance have been evaluated on many standard IEEE test systems and the results for standard IEEE-30 bus system, IEEE-57 bus system, and IEEE-118 bus system are presented.

  11. Formulation Predictive Dissolution (fPD) Testing to Advance Oral Drug Product Development: an Introduction to the US FDA Funded '21st Century BA/BE' Project.

    PubMed

    Hens, Bart; Sinko, Patrick; Job, Nicholas; Dean, Meagan; Al-Gousous, Jozef; Salehi, Niloufar; Ziff, Robert M; Tsume, Yasuhiro; Bermejo, Marival; Paixão, Paulo; Brasseur, James G; Yu, Alex; Talattof, Arjang; Benninghoff, Gail; Langguth, Peter; Lennernäs, Hans; Hasler, William L; Marciani, Luca; Dickens, Joseph; Shedden, Kerby; Sun, Duxin; Amidon, Gregory E; Amidon, Gordon L

    2018-06-23

    Over the past decade, formulation predictive dissolution (fPD) testing has gained increasing attention. Another mindset is pushed forward where scientists in our field are more confident to explore the in vivo behavior of an oral drug product by performing predictive in vitro dissolution studies. Similarly, there is an increasing interest in the application of modern computational fluid dynamics (CFD) frameworks and high-performance computing platforms to study the local processes underlying absorption within the gastrointestinal (GI) tract. In that way, CFD and computing platforms both can inform future PBPK-based in silico frameworks and determine the GI-motility-driven hydrodynamic impacts that should be incorporated into in vitro dissolution methods for in vivo relevance. Current compendial dissolution methods are not always reliable to predict the in vivo behavior, especially not for biopharmaceutics classification system (BCS) class 2/4 compounds suffering from a low aqueous solubility. Developing a predictive dissolution test will be more reliable, cost-effective and less time-consuming as long as the predictive power of the test is sufficiently strong. There is a need to develop a biorelevant, predictive dissolution method that can be applied by pharmaceutical drug companies to facilitate marketing access for generic and novel drug products. In 2014, Prof. Gordon L. Amidon and his team initiated a far-ranging research program designed to integrate (1) in vivo studies in humans in order to further improve the understanding of the intraluminal processing of oral dosage forms and dissolved drug along the gastrointestinal (GI) tract, (2) advancement of in vitro methodologies that incorporates higher levels of in vivo relevance and (3) computational experiments to study the local processes underlying dissolution, transport and absorption within the intestines performed with a new unique CFD based framework. Of particular importance is revealing the physiological variables determining the variability in in vivo dissolution and GI absorption from person to person in order to address (potential) in vivo BE failures. This paper provides an introduction to this multidisciplinary project, informs the reader about current achievements and outlines future directions. Copyright © 2018. Published by Elsevier B.V.

  12. Implementing ISO/IEEE 11073: proposal of two different strategic approaches.

    PubMed

    Martínez-Espronceda, M; Serrano, L; Martínez, I; Escayola, J; Led, S; Trigo, J; García, J

    2008-01-01

    This paper explains the challenges encountered during the ISO/IEEE 11073 standard implementation process. The complexity of the standard and the consequent heavy requirements, which have not encouraged software engineers to adopt the standard. The developing complexity evaluation drives us to propose two possible implementation strategies that cover almost all possible use cases and eases handling the standard by non-expert users. The first one is focused on medical devices (MD) and proposes a low-memory and low-processor usage technique. It is based on message patterns that allow simple functions to generate ISO/IEEE 11073 messages and to process them easily. In this way a framework for MDs can be obtained. Second one is focused on more powerful machines such as data loggers or gateways (aka. computer engines (CE)), which do not have the MDs' memory and processor usage constraints. For CEs a more intelligent and adaptative Plug&Play (P&P) solution is provided. It consists on a general platform that can access to any device supported by the standard. Combining both strategies will cut developing time for applications based on ISO/EEE 11073.

  13. THE BERKELEY DATA ANALYSIS SYSTEM (BDAS): AN OPEN SOURCE PLATFORM FOR BIG DATA ANALYTICS

    DTIC Science & Technology

    2017-09-01

    Evan Sparks, Oliver Zahn, Michael J. Franklin, David A. Patterson, Saul Perlmutter. Scientific Computing Meets Big Data Technology: An Astronomy ...Processing Astronomy Imagery Using Big Data Technology. IEEE Transaction on Big Data, 2016. Approved for Public Release; Distribution Unlimited. 22 [93

  14. Local Area Networks and the Learning Lab of the Future.

    ERIC Educational Resources Information Center

    Ebersole, Dennis C.

    1987-01-01

    Considers educational applications of local area computer networks and discusses industry standards for design established by the International Standards Organization (ISO) and Institute of Electrical and Electronic Engineers (IEEE). A futuristic view of a learning laboratory using a local area network is presented. (Author/LRW)

  15. Large-Scale Distributed Coalition Formation

    DTIC Science & Technology

    2009-09-01

    Ripeanu, Matei, Adriana Iamnitchi, and Ian Foster. “Mapping the Gnutella Network”. IEEE Internet Computing, 6(1):50–57, 2002. 78. Rowstron, Antony I...for Search. Working Papers 95-02-010, Santa Fe Institute, February 1995. 97. Xu, Yang, Paul Scerri, Bin Yu, Steven Okamoto, Michael Lewis, and Ka

  16. File System Virtual Appliances: Portable File System Implementations

    DTIC Science & Technology

    2009-05-01

    Mobile Computing Systems and Applications, Santa Cruz, CA, 1994. IEEE. [10] Michael Eisler , Peter Corbett, Michael Kazar, Daniel S. Nydick, and...Gingell, Joseph P. Moran, and William A. Shannon. Virtual Memory Architec- ture in SunOS. In USENIX Summer Conference, pages 81–94, Berkeley, CA, 1987

  17. Wireless Networks: New Meaning to Ubiquitous Computing.

    ERIC Educational Resources Information Center

    Drew, Wilfred, Jr.

    2003-01-01

    Discusses the use of wireless technology in academic libraries. Topics include wireless networks; standards (IEEE 802.11); wired versus wireless; why libraries implement wireless technology; wireless local area networks (WLANs); WLAN security; examples of wireless use at Indiana State University and Morrisville College (New York); and useful…

  18. Use of an online survey during an outbreak of clostridium perfringens in a retirement community-Arizona, 2012.

    PubMed

    Yasmin, Seema; Pogreba-Brown, Kristen; Stewart, Jennifer; Sunenshine, Rebecca

    2014-01-01

    An outbreak of gastrointestinal (GI) illness among retirement community residents was reported to the Maricopa County Department of Public Health. Online surveys can be useful for rapid investigation of disease outbreaks, especially when local health departments lack time and resources to perform telephone interviews. Online survey utility among older populations, which may lack computer access or literacy, has not been defined. To investigate and implement prevention measures for a GI outbreak and assess the utility of an online survey among retirement community residents. A retrospective cohort investigation was conducted using an online survey distributed through the retirement community e-mail listserv; a follow-up telephone survey was conducted to assess computer literacy and Internet access. A case was defined as any GI illness occurring among residents during March 1-14, 2012. A barbecue in a retirement community of 3000 residents. Retirement community residents. Residents were directed to discard leftover food and seek health care for symptoms. A telephone survey was conducted to assess the utility of online surveys in this population. Computer literacy and Internet access of retirement community residents. Of 1000 residents on the listserv, 370 (37%) completed the online survey (mean age, 69.7 years; 60.6% women); 66 residents (17.8%) reported a GI illness after the barbecue, 63 (95.5%) reported diarrhea, and 5 (7.6%) reported vomiting. Leftover beef from an attendee's refrigerator grew Clostridium perfringens. Of 552 residents contacted by telephone, 113 completed the telephone survey (mean age, 71.3 years; 63.3% women), 101 (89.4%) reported the ability to send e-mail, 82 (81.2%) checked e-mail daily, and 28 (27.7%) checked e-mail on a handheld device. The attack rate was 17.8% for online versus 2.7% for telephone respondents (P < .001). This outbreak demonstrated the utility of an online survey to rapidly collect information and implement prevention measures among an older demographic.

  19. Ultrasound-Based Guidance for Partial Breast Irradiation Therapy

    DTIC Science & Technology

    2012-01-01

    displace- 0278-0062/$20.00 © IEEE Authorized licensed use limited to: IEEE Xplore . Downloaded on January 5, 2009 at 17:37 from IEEE Xplore . Restrictions...Authorized licensed use limited to: IEEE Xplore . Downloaded on January 5, 2009 at 17:37 from IEEE Xplore . Restrictions apply. RIVAZ et al...better CNR values: the Authorized licensed use limited to: IEEE Xplore . Downloaded on January 5, 2009 at 17:37 from IEEE Xplore . Restrictions apply

  20. Confabulation Based Real-time Anomaly Detection for Wide-area Surveillance Using Heterogeneous High Performance Computing Architecture

    DTIC Science & Technology

    2015-06-01

    system accuracy. The AnRAD system was also generalized for the additional application of network intrusion detection . A self-structuring technique...to Host- based Intrusion Detection Systems using Contiguous and Discontiguous System Call Patterns,” IEEE Transactions on Computer, 63(4), pp. 807...square kilometer areas. The anomaly recognition and detection (AnRAD) system was built as a cogent confabulation network . It represented road

  1. Terahertz Radiation: A Non-contact Tool for the Selective Stimulation of Biological Responses in Human Cells

    DTIC Science & Technology

    2014-01-01

    computational and empirical dosimetric tools [31]. For the computational dosimetry, we employed finite-dif- ference time- domain (FDTD) modeling techniques to...temperature-time data collected for a well exposed to THz radiation using finite-difference time- domain (FDTD) modeling techniques and thermocouples... like )). Alter- ation in the expression of such genes underscores the signif- 62 IEEE TRANSACTIONS ON TERAHERTZ SCIENCE AND TECHNOLOGY, VOL. 6, NO. 1

  2. JPRS Report, Science & Technology. China.

    DTIC Science & Technology

    1989-03-29

    Commun ., Vol COM-29, No 6, pp 895-901, June 1981. [4] R.C. Titsworth , "A Boolean-Function-Multiplexed Telemetry System," IEEE Trans, on SET, pp 42...Reagents 39 Gene-Engineered Human Epithelium Growth Factor (hEGF) 39 Superfine Snake Venom 39 COMPUTERS Ai Computer System LISP-MI [Zheng Shouqi, et...XUEBAO, No 3, Jun 88] 134 Coordinated Development of Microwave, Optical Communications [Zhang Xu; DIANXIN KUAIBAO, No 11, Nov 88] 143 Error

  3. Portable Map-Reduce Utility for MIT SuperCloud Environment

    DTIC Science & Technology

    2015-09-17

    Reuther, A. Rosa, C. Yee, “Driving Big Data With Big Compute,” IEEE HPEC, Sep 10-12, 2012, Waltham, MA. [6] Apache Hadoop 1.2.1 Documentation: HDFS... big data architecture, which is designed to address these challenges, is made of the computing resources, scheduler, central storage file system...databases, analytics software and web interfaces [1]. These components are common to many big data and supercomputing systems. The platform is

  4. Face and construct validity of a computer-based virtual reality simulator for ERCP.

    PubMed

    Bittner, James G; Mellinger, John D; Imam, Toufic; Schade, Robert R; Macfadyen, Bruce V

    2010-02-01

    Currently, little evidence supports computer-based simulation for ERCP training. To determine face and construct validity of a computer-based simulator for ERCP and assess its perceived utility as a training tool. Novice and expert endoscopists completed 2 simulated ERCP cases by using the GI Mentor II. Virtual Education and Surgical Simulation Laboratory, Medical College of Georgia. Outcomes included times to complete the procedure, reach the papilla, and use fluoroscopy; attempts to cannulate the papilla, pancreatic duct, and common bile duct; and number of contrast injections and complications. Subjects assessed simulator graphics, procedural accuracy, difficulty, haptics, overall realism, and training potential. Only when performance data from cases A and B were combined did the GI Mentor II differentiate novices and experts based on times to complete the procedure, reach the papilla, and use fluoroscopy. Across skill levels, overall opinions were similar regarding graphics (moderately realistic), accuracy (similar to clinical ERCP), difficulty (similar to clinical ERCP), overall realism (moderately realistic), and haptics. Most participants (92%) claimed that the simulator has definite training potential or should be required for training. Small sample size, single institution. The GI Mentor II demonstrated construct validity for ERCP based on select metrics. Most subjects thought that the simulated graphics, procedural accuracy, and overall realism exhibit face validity. Subjects deemed it a useful training tool. Study repetition involving more participants and cases may help confirm results and establish the simulator's ability to differentiate skill levels based on ERCP-specific metrics.

  5. Optimal Processor Assignment for Pipeline Computations

    DTIC Science & Technology

    1991-10-01

    the use of ratios: initially each task is assigned a procesbuor2 the remaining proceborb are distributed in proportion to the quantities f,(1), 1 < i...algorithmns. IEEE Trans. onl Parallel and Distributed Systemns, 1 (4):470-499, October 1990. [26] P. Al. Kogge. The Architeture of Pipelined Comnputers

  6. Security Enhancement of Littoral Combat Ship Class Utilizing an Autonomous Mustering and Pier Monitoring System

    DTIC Science & Technology

    2010-03-01

    allows the programmer to use the English language in an expressive manor while still maintaining the logical structure of a programming language ( Pressman ...and Choudhury Tanzeem. 2000. Face Recognition for Smart Environments, IEEE Computer, pp. 50–55. Pressman , Roger. 2010. Software Engineering A

  7. Extending the IEEE-LTSA.

    ERIC Educational Resources Information Center

    Voskamp, Jorg; Hambach, Sybille

    An Internet-based course management system has been under development at the Fraunhofer-Institute for Computer Graphics Rostock (Germany) for the past 5 years. It is used by experts for distributing their courses via the Internet and by students for learning with the material distributed. The "Course Management System for WWW--CMS-W3"…

  8. Towards Formalizing the Java Security Architecture of JDK 1.2

    DTIC Science & Technology

    1998-01-01

    and Richard E. Newman for their contributions to this paper. References 1. Balfanz , D. and Gong, L.: Experience with Secure Multi-Processing in Java...Privacy, IEEE Computer Society, Oakland, California, Pages 122-136, 1992. 18. Wallach, D. S., Balfanz , D., Dean, D., and Felton, E. W.: Extensible

  9. Device-Enabled Authorization in the Grey System

    DTIC Science & Technology

    2005-02-01

    proof checker. Journal of Automated Reasoning 31(3-4):231–260, 2003. [7] D. Balfanz , D. Dean, and M. Spreitzer. A security infrastructure for...distributed Java applications. In Proceedings of the 21st IEEE Symposium on Security and Privacy, May 2002. [8] D. Balfanz and E. Felten. Hand-held computers

  10. Managing Parallelism and Resources in Scientific Dataflow Programs

    DTIC Science & Technology

    1990-03-01

    1983. [52] K. Hiraki , K. Nishida, S. Sekiguchi, and T. Shimada. Maintainence architecture and its LSI implementation of a dataflow computer with a... Hiraki , and K. Nishida. An architecture of a data flow machine and its evaluation. In Proceedings of CompCon 84, pages 486-490. IEEE, 1984. [84] N

  11. Developing Software to Use Parallel Processing Effectively

    DTIC Science & Technology

    1988-10-01

    Experience, Vol 15(6), June 1985, p53 Gajski85 Gajski , Daniel D. and Jih-Kwon Peir, "Essential Issues in Multiprocessor Systems", IEEE Computer, June...Treleaven (eds.), Springer-Verlag, pp. 213-225 (June 1987). Kuck83 David Kuck, Duncan Lawrie, Ron Cytron, Ahmed Sameh and Daniel Gajski , The Architecture and

  12. Partial Bibliography of Work on Expert Systems,

    DTIC Science & Technology

    1982-12-01

    Bibliography: AAAI American Association for Artificial Intelligence ACM Association for Computing Machinery AFIPS American Federation of Information...Processing Societies ECAI European Conference on Artificial Intelligence IEEE Institute for Electrical and Electronic Engineers IFIPS International...Federation of Information Processing Societies IJCAI International Joint Conferences on Artificial Intelligence SIGPLAN ACM Special Interest Group on

  13. Communication-Efficient Arbitration Models for Low-Resolution Data Flow Computing

    DTIC Science & Technology

    1988-12-01

    Given graph G = (V, E), weights w (v) for each v e V and L (e) for each e c E, and positive integers B and J, find a partition of V into disjoint...MIT/LCS/TR-218, Cambridge, Mass. Agerwala, Tilak, February 1982, "Data Flow Systems", Computer, pp. 10-13. Babb, Robert G ., July 1984, "Parallel...Processing with Large-Grain Data Flow Techniques," IEEE Computer 17, 7, pp. 55-61. Babb, Robert G ., II, Lise Storc, and William C. Ragsdale, 1986, "A Large

  14. CONTOUR; a modification of G.I. Evenden's general purpose contouring program

    USGS Publications Warehouse

    Godson, R.H.; Webring, M.W.

    1982-01-01

    A contouring program written for the DEC-10 computer (Evenden, 1975) has been modified and enhanced to operate on a Honeywell Multics 68/80 computer. The program uses a device independent plotting system (Wahl, 1977) so that output can be directed to any of several plotting devices by simply specifying one input variable.

  15. Application of computational models to estimate organ radiation dose in rainbow trout from uptake of molybdenum-99 with comparison to iodine-131.

    PubMed

    Martinez, N E; Johnson, T E; Pinder, J E

    2016-01-01

    This study compares three anatomical phantoms for rainbow trout (Oncorhynchus mykiss) for the purpose of estimating organ radiation dose and dose rates from molybdenum-99 ((99)Mo) uptake in the liver and GI tract. Model comparison and refinement is important to the process of determining accurate doses and dose rates to the whole body and the various organs. Accurate and consistent dosimetry is crucial to the determination of appropriate dose-effect relationships for use in environmental risk assessment. The computational phantoms considered are (1) a geometrically defined model employing anatomically relevant organ size and location, (2) voxel reconstruction of internal anatomy obtained from CT imaging, and (3) a new model utilizing NURBS surfaces to refine the model in (2). Dose Conversion Factors (DCFs) for whole body as well as selected organs of O. mykiss were computed using Monte Carlo modeling and combined with empirical models for predicting activity concentration to estimate dose rates and ultimately determine cumulative radiation dose (μGy) to selected organs after several half-lives of (99)Mo. The computational models provided similar results, especially for organs that were both the source and target of radiation (less than 30% difference between all models). Values in the empirical model as well as the 14 day cumulative organ doses determined from (99)Mo uptake are compared to similar models developed previously for (131)I. Finally, consideration is given to treating the GI tract as a solid organ compared to partitioning it into gut contents and GI wall, which resulted in an order of magnitude difference in estimated dose for most organs. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Interoperability in digital electrocardiography: harmonization of ISO/IEEE x73-PHD and SCP-ECG.

    PubMed

    Trigo, Jesús D; Chiarugi, Franco; Alesanco, Alvaro; Martínez-Espronceda, Miguel; Serrano, Luis; Chronaki, Catherine E; Escayola, Javier; Martínez, Ignacio; García, José

    2010-11-01

    The ISO/IEEE 11073 (x73) family of standards is a reference frame for medical device interoperability. A draft for an ECG device specialization (ISO/IEEE 11073-10406-d02) has already been presented to the Personal Health Device (PHD) Working Group, and the Standard Communications Protocol for Computer-Assisted ElectroCardioGraphy (SCP-ECG) Standard for short-term diagnostic ECGs (EN1064:2005+A1:2007) has recently been approved as part of the x73 family (ISO 11073-91064:2009). These factors suggest the coordinated use of these two standards in foreseeable telecardiology environments, and hence the need to harmonize them. Such harmonization is the subject of this paper. Thus, a mapping of the mandatory attributes defined in the second draft of the ISO/IEEE 11073-10406-d02 and the minimum SCP-ECG fields is presented, and various other capabilities of the SCP-ECG Standard (such as the messaging part) are also analyzed from an x73-PHD point of view. As a result, this paper addresses and analyzes the implications of some inconsistencies in the coordinated use of these two standards. Finally, a proof-of-concept implementation of the draft x73-PHD ECG device specialization is presented, along with the conversion from x73-PHD to SCP-ECG. This paper, therefore, provides recommendations for future implementations of telecardiology systems that are compliant with both x73-PHD and SCP-ECG.

  17. A Parallel Neuromorphic Text Recognition System and Its Implementation on a Heterogeneous High-Performance Computing Cluster

    DTIC Science & Technology

    2013-01-01

    M. Ahmadi, and M. Shridhar, “ Handwritten Numeral Recognition with Multiple Features and Multistage Classifiers,” Proc. IEEE Int’l Symp. Circuits...ARTICLE (Post Print) 3. DATES COVERED (From - To) SEP 2011 – SEP 2013 4. TITLE AND SUBTITLE A PARALLEL NEUROMORPHIC TEXT RECOGNITION SYSTEM AND ITS...research in computational intelligence has entered a new era. In this paper, we present an HPC-based context-aware intelligent text recognition

  18. Preliminary Development of a Computational Model of a Dielectric Barrier Discharge

    DTIC Science & Technology

    2004-12-01

    Gerhard Pietsch . "Microdischarges in Air-Fed Ozonizers," Journal of Physics D: Applied Physics, Vol 24, 1991, pp 564-572. 14 Baldur Eliasson. "Modeling...Gibalov and Gerhard Pietsch . "Two-dimensional Modeling of the Dielectric Barrier Discharge in Air," Plasma Sources Science Technology, 1 (1992), pp. 166...Computer Modeling," IEEE Transactions on Plasma Science, 27 (1), February 1999, pp 36-37. 19 Valentin I Gibalov and Gerhard J. Pietsch . "The

  19. Networking DEC and IBM computers

    NASA Technical Reports Server (NTRS)

    Mish, W. H.

    1983-01-01

    Local Area Networking of DEC and IBM computers within the structure of the ISO-OSI Seven Layer Reference Model at a raw signaling speed of 1 Mops or greater are discussed. After an introduction to the ISO-OSI Reference Model nd the IEEE-802 Draft Standard for Local Area Networks (LANs), there follows a detailed discussion and comparison of the products available from a variety of manufactures to perform this networking task. A summary of these products is presented in a table.

  20. Robust Multi-Agent Sensor Network Systems

    DTIC Science & Technology

    2012-05-08

    Localization on the Sphere, International Journal of Intelligent Defence Support System, Vol. 4, no. 4, 2011, pp. 328-350. Quality of Network... Quality of Service (QoS). The following standards are included in the IEEE 1609 standard family: IEEE P1609.0, IEEE P1609.1, IEEE P1609.2, IEEE P1609.3...protocols to support safety services in ITS,” in IEEE International Conference on Emerging Technologies and Factory Au- tomation (ETFA), 2008, pp. 1189

  1. Numerical and experimental analysis of factors leading to suture dehiscence after Billroth II gastric resection.

    PubMed

    Cvetkovic, Aleksandar M; Milasinovic, Danko Z; Peulic, Aleksandar S; Mijailovic, Nikola V; Filipovic, Nenad D; Zdravkovic, Nebojsa D

    2014-11-01

    The main goal of this study was to numerically quantify risk of duodenal stump blowout after Billroth II (BII) gastric resection. Our hypothesis was that the geometry of the reconstructed tract after BII resection is one of the key factors that can lead to duodenal dehiscence. We used computational fluid dynamics (CFD) with finite element (FE) simulations of various models of BII reconstructed gastrointestinal (GI) tract, as well as non-perfused, ex vivo, porcine experimental models. As main geometrical parameters for FE postoperative models we have used duodenal stump length and inclination between gastric remnant and duodenal stump. Virtual gastric resection was performed on each of 3D FE models based on multislice Computer Tomography (CT) DICOM. According to our computer simulation the difference between maximal duodenal stump pressures for models with most and least preferable geometry of reconstructed GI tract is about 30%. We compared the resulting postoperative duodenal pressure from computer simulations with duodenal stump dehiscence pressure from the experiment. Pressure at duodenal stump after BII resection obtained by computer simulation is 4-5 times lower than the dehiscence pressure according to our experiment on isolated bowel segment. Our conclusion is that if the surgery is performed technically correct, geometry variations of the reconstructed GI tract by themselves are not sufficient to cause duodenal stump blowout. Pressure that develops in the duodenal stump after BII resection using omega loop, only in the conjunction with other risk factors can cause duodenal dehiscence. Increased duodenal pressure after BII resection is risk factor. Hence we recommend the routine use of Roux en Y anastomosis as a safer solution in terms of resulting intraluminal pressure. However, if the surgeon decides to perform BII reconstruction, results obtained with this methodology can be valuable. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  2. Advanced Visual and Instruction Systems for Maintenance Support (AVIS-MS)

    DTIC Science & Technology

    2006-12-01

    Hayashi , "Augmentable Reality: Situated Communication through Physical and Digital Spaces," Proc. 2nd Int’l Symp. Wearable Computers, IEEE CS Press...H. Ohno , "An Optical See-through Display for Mutual Occlusion of Real and Virtual Environments," Proc. Int’l Symp. Augmented Reality 2000 (ISARO0

  3. Exploiting Semi-Directional Transceivers for Localization in Communication Systems

    DTIC Science & Technology

    2006-03-01

    some of those late nights. To Patrick S. and Maura D., you guys made AFIT home away from home for me. Additionally to all of my classmates and...conference on Mobile com- puting and networking, 151–159. IEEE Computer Society, ACM Press, Berkeley, CA, November 1995. 6. Kelly , Ian and Alcherio Martinoli

  4. Issues in the Convergence of Control with Communication and Computation

    DTIC Science & Technology

    2004-10-04

    Library/Upload/116/Cal1.doc. [42] M. H. Shwehdi and A. Z. Khan, “A power line data communication interface using spread spectrum technology in home ... automation ,” IEEE Transactions on Power Delivery, vol. 11, pp. 1232–1237, July 1996. ISSN: 0885-8977. [43] R. G. Olsen, “Technical considerations for

  5. Motion and Structure Estimation of Manoeuvring Objects in Multiple- Camera Image Sequences

    DTIC Science & Technology

    1992-11-01

    and Speckert [23], Gennery [24], Hallman [25], Legters and Young [26], Stuller and Krishnamurthy [27], Wu et al. [381, Matthies, Kanade, and Szeliski...26] G.R. Legters , T.Y. Young, "A mathematical model for computer image track- ing," IEEE Transactions on Pattern Analysis and Machine Intelligence

  6. Multi-scale Computational Electromagnetics for Phenomenology and Saliency Characterization in Remote Sensing

    DTIC Science & Technology

    2014-06-12

    interferometry and polarimetry . In the paper, the model was used to simulate SAR data for Mangrove (tropical) and Nezer (temperate) forests for P-band and...Scattering Model Applied to Radiometry, Interferometry, and Polarimetry at P- and L-Band. IEEE Transactions on Geoscience and Remote Sensing 44(4): 849

  7. Proceedings 3rd NASA/IEEE Workshop on Formal Approaches to Agent-Based Systems (FAABS-III)

    NASA Technical Reports Server (NTRS)

    Hinchey, Michael (Editor); Rash, James (Editor); Truszkowski, Walt (Editor); Rouff, Christopher (Editor)

    2004-01-01

    These preceedings contain 18 papers and 4 poster presentation, covering topics such as: multi-agent systems, agent-based control, formalism, norms, as well as physical and biological models of agent-based systems. Some applications presented in the proceedings include systems analysis, software engineering, computer networks and robot control.

  8. Processes in KaffeOS: Isolation, Resource Management, and Sharing in Java

    DTIC Science & Technology

    2000-04-01

    separation of garbage collection costs is not possible. Balfanz and Gong [2] describe a multi- processing JVM developed to explore the secu- rity...line in Java. In Proc. of the 7th HotOS, Rio Rico, AZ, Mar. 1999. IEEE Computer Society. [2] D. Balfanz and L. Gong. Experience with secure multi

  9. Surveillance of Space - Optimal Use of Complementary Sensors for Maximum Efficiency

    DTIC Science & Technology

    2006-04-01

    as track - before - detect [4] have been shown to allow improved sensitivity. This technique employs fast running algorithms and computing power to pre...Multifunction Radar” IEEE Signal Processing Magazine, January 2006. [4] Wallace W R “The Use of Track - Before - Detect in Pulse-Doppler Radar” IEE 490, Radar

  10. Image Based Synthesis for Airborne Minefield Data

    DTIC Science & Technology

    2005-12-01

    Jia, and C-K. Tang, "Image repairing: robust image synthesis by adaptive ND tensor voting ", Proceedings of the IEEE, Computer Society Conference on...utility is capable to synthesize a single frame data as well as list of frames along a flight path. The application is developed in MATLAB -6.5 using the

  11. Image Perception Wavelet Simulation and Enhancement for the Visually Impaired.

    DTIC Science & Technology

    1994-12-01

    and Computational Harmonic Analysis, 1:54-81 (1993). 6. Cornsweet, Tom N. "The Staircase-Method in Psychophysics," The American Journal of Psychology ...of a Visual Model," Proceedings of the IEEE, 60(7):828-842 (July 1972). 33. Taylor, M. M. and C Douglas Creelman . "PEST: Efficient Estimates on

  12. Women in biomedical engineering and health informatics and its impact on gender representation for accepted publications at IEEE EMBC 2007.

    PubMed

    McGregor, Carolyn; Smith, Kathleen P; Percival, Jennifer

    2008-01-01

    The study of women within the professions of Engineering and Computer Science has consistently been found to demonstrate women as a minority within these professions. However none of that previous work has assessed publication behaviours based on gender. This paper presents research findings on gender distribution of authors of accepted papers for the IEEE Engineering and Medicine Society annual conference for 2007 (EMBC '07) held in Lyon, France. This information is used to present a position statement of the current state of gender representation for conference publication within the domain of biomedical engineering and health informatics. Issues in data preparation resulting from the lack of inclusion of gender in information gathered from accepted authors are presented and discussed.

  13. Message From the Editor for Contributions to the 2016 Real Time Conference Issue of TNS

    NASA Astrophysics Data System (ADS)

    Schmeling, Sascha Marc

    2017-06-01

    This issue of the IEEE Transactions on Nuclear Science (TNS) is devoted to the 20th IEEE-NPSS Real Time Conference (RT2016) on Computing Applications in Nuclear and Plasma Sciences held in Padua, Italy, in June 2016. A total of 90 papers presented at the conference were submitted for possible publication in TNS. This conference issue presents 46 papers, which have been accepted so far after a thorough peer review process. These contributions come from a very broad range of fields of application, including Astrophysics, Medical Imaging, Nuclear and Plasma Physics, Particle Accelerators, and Particle Physics Experiments. Several papers were close to being accepted but did not make it into this special issue. They will be considered for further publication.

  14. In Vivo Predictive Dissolution (IPD) and Biopharmaceutical Modeling and Simulation: Future Use of Modern Approaches and Methodologies in a Regulatory Context.

    PubMed

    Lennernäs, H; Lindahl, A; Van Peer, A; Ollier, C; Flanagan, T; Lionberger, R; Nordmark, A; Yamashita, S; Yu, L; Amidon, G L; Fischer, V; Sjögren, E; Zane, P; McAllister, M; Abrahamsson, B

    2017-04-03

    The overall objective of OrBiTo, a project within Innovative Medicines Initiative (IMI), is to streamline and optimize the development of orally administered drug products through the creation and efficient application of biopharmaceutics tools. This toolkit will include both experimental and computational models developed on improved understanding of the highly dynamic gastrointestinal (GI) physiology relevant to the GI absorption of drug products in both fasted and fed states. A part of the annual OrBiTo meeting in 2015 was dedicated to the presentation of the most recent progress in the development of the regulatory use of PBPK in silico modeling, in vivo predictive dissolution (IPD) tests, and their application to biowaivers. There are still several areas for improvement of in vitro dissolution testing by means of generating results relevant for the intraluminal conditions in the GI tract. The major opportunity is probably in combining IPD testing and physiologically based in silico models where the in vitro data provide input to the absorption predictions. The OrBiTo project and other current research projects include definition of test media representative for the more distal parts of the GI tract, models capturing supersaturation and precipitation phenomena, and influence of motility waves on shear and other forces of hydrodynamic origin, addressing the interindividual variability in composition and characteristics of GI fluids, food effects, definition of biorelevant buffer systems, and intestinal water volumes. In conclusion, there is currently a mismatch between the extensive industrial usage of modern in vivo predictive tools and very limited inclusion of such data in regulatory files. However, there is a great interest among all stakeholders to introduce recent progresses in prediction of in vivo GI drug absorption into regulatory context.

  15. Novel Holistic Approaches for Overcoming Therapy Resistance in Pancreatic and Colon Cancers.

    PubMed

    Sarkar, Fazlul H

    2016-01-01

    Gastrointestinal (GI) cancers, such as of the colon and pancreas, are highly resistant to both standard and targeted therapeutics. Therapy-resistant and heterogeneous GI cancers harbor highly complex signaling networks (the resistome) that resist apoptotic programming. Commonly used gemcitabine or platinum-based regimens fail to induce meaningful (i.e. disease-reversing) perturbations in the resistome, resulting in high rates of treatment failure. The GI cancer resistance networks are, in part, due to interactions between parallel signaling and aberrantly expressed microRNAs (miRNAs) that collectively promote the development and survival of drug-resistant cancer stem cells with epithelial-to-mesenchymal transition (EMT) characteristics. The lack of understanding of the resistance networks associated with this subpopulation of cells as well as reductionist, single protein-/pathway-targeted approaches have made 'effective drug design' a difficult task. We propose that the successful design of novel therapeutic regimens to target drug-resistant GI tumors is only possible if network-based drug avenues and agents, in particular 'natural agents' with no known toxicity, are correctly identified. Natural agents (dietary agents or their synthetic derivatives) can individually alter miRNA profiles, suppress EMT pathways and eliminate cancer stem-like cells that derive from pancreatic cancer and colon cancer, by partially targeting multiple yet meaningful networks within the GI cancer resistome. However, the efficacy of these agents as combinations (e.g. consumed in the diet) against this resistome has never been studied. This short review article provides an overview of the different challenges involved in the understanding of the GI resistome, and how novel computational biology can help in the design of effective therapies to overcome resistance. © 2015 S. Karger AG, Basel.

  16. A Review of the Suitability of Available Computer Aided Software Engineering (CASE) Tools for the Small Software Development Environment

    DTIC Science & Technology

    1989-07-11

    LITERATURE CITED [Boeh73] Boehm, Barry W., "Software and its Impact: A Quantitative Assessment," Datamation, 19, 5, (May 1973), pp 48-59. [Boeh76...Boehm, Barry W., "Software Engineering," IEEE Transactions on Computers, C-25, 12, (December 1976), pp 1226-1241. [Boeh81a] Boehm, Barry W., Software...Engineering Economics, Prentice-Hall, Inc., Englewood Cliffs, NJ, (1981). [Boeh8lb] Boehm, Barry W., "An Experiment in Small Scale Application Software

  17. Memristive Computational Architecture of an Echo State Network for Real-Time Speech Emotion Recognition

    DTIC Science & Technology

    2015-05-28

    recognition is simpler and requires less computational resources compared to other inputs such as facial expressions . The Berlin database of Emotional ...Processing Magazine, IEEE, vol. 18, no. 1, pp. 32– 80, 2001. [15] K. R. Scherer, T. Johnstone, and G. Klasmeyer, “Vocal expression of emotion ...Network for Real-Time Speech- Emotion Recognition 5a. CONTRACT NUMBER IN-HOUSE 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 62788F 6. AUTHOR(S) Q

  18. Space-division-multiplexed transmission of 3x3 multiple-input multiple-output wireless signals over conventional graded-index multimode fiber.

    PubMed

    Lei, Yi; Li, Jianqiang; Fan, Yuting; Yu, Dawei; Fu, Songnian; Yin, Feifei; Dai, Yitang; Xu, Kun

    2016-12-12

    In this paper, we experimentally demonstrate space-division-multiplexed (SDM) transmission of IEEE 802.11ac-compliant 3-spatial-stream WLAN signals over 3 spatial modes of conventional 50um graded-index (GI) multimode fiber (MMF) employing non-mode-selective 3D-waveguide photonic lantern. Two kinds of scenarios, including fiber-only transmission and fiber-wireless hybrid transmission, were investigated by measuring error vector magnitude (EVM) performance for each stream and condition number (CN) of the channel matrix. The experimental results show that, SDM-based MMF link could offer a CN< 20dB well-conditioned MIMO channel over up to 1km fiber length within 0-6GHz, achieving as low as 2.38%, 2.97% and 2.11% EVM performance for 1km MMF link at 2.4GHz, 5.8GHz, and 200m MMF link followed by 1m air distance at 2.7GHz, respectively. These results indicate the possibility to distribute wireless MIMO signals over existing in-building commercially-available MMFs with enormous cost-saving.

  19. Distributed GPU Computing in GIScience

    NASA Astrophysics Data System (ADS)

    Jiang, Y.; Yang, C.; Huang, Q.; Li, J.; Sun, M.

    2013-12-01

    Geoscientists strived to discover potential principles and patterns hidden inside ever-growing Big Data for scientific discoveries. To better achieve this objective, more capable computing resources are required to process, analyze and visualize Big Data (Ferreira et al., 2003; Li et al., 2013). Current CPU-based computing techniques cannot promptly meet the computing challenges caused by increasing amount of datasets from different domains, such as social media, earth observation, environmental sensing (Li et al., 2013). Meanwhile CPU-based computing resources structured as cluster or supercomputer is costly. In the past several years with GPU-based technology matured in both the capability and performance, GPU-based computing has emerged as a new computing paradigm. Compare to traditional computing microprocessor, the modern GPU, as a compelling alternative microprocessor, has outstanding high parallel processing capability with cost-effectiveness and efficiency(Owens et al., 2008), although it is initially designed for graphical rendering in visualization pipe. This presentation reports a distributed GPU computing framework for integrating GPU-based computing within distributed environment. Within this framework, 1) for each single computer, computing resources of both GPU-based and CPU-based can be fully utilized to improve the performance of visualizing and processing Big Data; 2) within a network environment, a variety of computers can be used to build up a virtual super computer to support CPU-based and GPU-based computing in distributed computing environment; 3) GPUs, as a specific graphic targeted device, are used to greatly improve the rendering efficiency in distributed geo-visualization, especially for 3D/4D visualization. Key words: Geovisualization, GIScience, Spatiotemporal Studies Reference : 1. Ferreira de Oliveira, M. C., & Levkowitz, H. (2003). From visual data exploration to visual data mining: A survey. Visualization and Computer Graphics, IEEE Transactions on, 9(3), 378-394. 2. Li, J., Jiang, Y., Yang, C., Huang, Q., & Rice, M. (2013). Visualizing 3D/4D Environmental Data Using Many-core Graphics Processing Units (GPUs) and Multi-core Central Processing Units (CPUs). Computers & Geosciences, 59(9), 78-89. 3. Owens, J. D., Houston, M., Luebke, D., Green, S., Stone, J. E., & Phillips, J. C. (2008). GPU computing. Proceedings of the IEEE, 96(5), 879-899.

  20. Virtual Reality Simulation of the Effects of Microgravity in Gastrointestinal Physiology

    NASA Technical Reports Server (NTRS)

    Compadre, Cesar M.

    1998-01-01

    The ultimate goal of this research is to create an anatomically accurate three-dimensional (3D) simulation model of the effects of microgravity in gastrointestinal physiology and to explore the role that such changes may have in the pharmacokinetics of drugs given to the space crews for prevention or therapy. To accomplish this goal the specific aims of this research are: 1) To generate a complete 3-D reconstructions of the human GastroIntestinal (GI) tract of the male and female Visible Humans. 2) To develop and implement time-dependent computer algorithms to simulate the GI motility using the above 3-D reconstruction.

  1. Face Detection and Modeling for Recognition

    DTIC Science & Technology

    2002-01-01

    gi st er ed ra n ge an d co lo r im ag es . 16 F ig u re 1. 12 . S y st em d ia gr...it h an d w it h ou t th e tr an sf or m ar e sh ow n . F or ea ch ex am p le , th e im ag es sh ow n in th e fi rs t co lu m n ar e sk in re gi on s...software/products /perflib/ipl/index.htm>. [187] Intel Open Source Computer Vision Library, <http://developer.intel.com/ soft- ware/opensource/cvfl/ opencv

  2. Differentiating malignant from benign gastric mucosal lesions with quantitative analysis in dual energy spectral computed tomography: Initial experience.

    PubMed

    Meng, Xiaoyan; Ni, Cheng; Shen, Yaqi; Hu, Xuemei; Chen, Xiao; Li, Zhen; Hu, Daoyu

    2017-01-01

    To investigate the value of quantitative analysis in dual energy spectral computed tomography (DESCT) for differentiating malignant gastric mucosal lesions from benign gastric mucosal lesions (including gastric inflammation [GI] and normal gastric mucosa [NGM]). This study was approved by the ethics committee, and all patients provided written informed consent. A total of 161 consecutive patients (63 with gastric cancer [GC], 48 with GI, and 50 with NGM) who underwent dual-phase contrast enhanced DESCT scans in the arterial phase (AP) and portal venous phase (PVP) were included in this study. Iodine concentration (IC) in lesions was derived from the iodine-based material-decomposition images and normalized to that in the aorta to obtain normalized IC (nIC). The ratios of IC and nIC between the AP and PVP were calculated. Diagnostic confidence for GC and GI was evaluated with reviewing the features including gastric wall thickness, focal, and eccentric on the conventional polychromatic images. All statistical analyses were performed by using statistical software SPSS 17.0 (SPSS, Chicago, IL). IC and nIC in GC differed significantly from those in GI and NGM, except for nICAP in comparing GC with GI. Mean nIC values of GC (0.18 ± 0.06 in AP and 0.62 ± 0.16 in PVP) were significantly higher than that of NGM (0.12 ± 0.03 in AP and 0.37 ± 0.08 in PVP) (all P < 0.05). There was also significant difference for IC values in GC, GI, and NGM (24.19 ± 8.27, 19.07 ± 5.82, and 13.61 ± 2.52 mg/mL, respectively, in AP and 28.00 ± 7.01, 24.66 ± 6.55, and 16.94 ± 3.06 mg/mL, respectively, in PVP). Based on Receiver Operating Characteristic Curve analysis, nIC and IC in PVP had high sensitivities of 88.89% and 90.48%, respectively, in differentiating GC from NGM, while the sensitivities were 71.43% and 88.89% during AP. Ratios IC and nIC ratios did not provide adequate diagnostic accuracy with their area under curves less than 0.65. With the conventional features, the diagnostic accuracies for GC and GI were 75.0% and 98.0%, respectively. Quantitative analysis of DESCT imaging parameters for gastric mucosa, such as nIC and IC, is useful for differentiating malignant from benign gastric mucosal lesions.

  3. 46 CFR 111.60-3 - Cable application.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... IEEE 1580 must meet the provisions for cable application of section 24 of IEEE 45-2002 (both... incorporated by reference; see 46 CFR 110.10-1) must meet section 24 of IEEE 45-2002, except 24.6.1, 24.6.7... constructed according to IEEE 1580 must be applied in accordance with Table 25, Note 6, of IEEE 45-2002. (2...

  4. Defining the IEEE-854 floating-point standard in PVS

    NASA Technical Reports Server (NTRS)

    Miner, Paul S.

    1995-01-01

    A significant portion of the ANSI/IEEE-854 Standard for Radix-Independent Floating-Point Arithmetic is defined in PVS (Prototype Verification System). Since IEEE-854 is a generalization of the ANSI/IEEE-754 Standard for Binary Floating-Point Arithmetic, the definition of IEEE-854 in PVS also formally defines much of IEEE-754. This collection of PVS theories provides a basis for machine checked verification of floating-point systems. This formal definition illustrates that formal specification techniques are sufficiently advanced that is is reasonable to consider their use in the development of future standards.

  5. DoS detection in IEEE 802.11 with the presence of hidden nodes

    PubMed Central

    Soryal, Joseph; Liu, Xijie; Saadawi, Tarek

    2013-01-01

    The paper presents a novel technique to detect Denial of Service (DoS) attacks applied by misbehaving nodes in wireless networks with the presence of hidden nodes employing the widely used IEEE 802.11 Distributed Coordination Function (DCF) protocols described in the IEEE standard [1]. Attacker nodes alter the IEEE 802.11 DCF firmware to illicitly capture the channel via elevating the probability of the average number of packets transmitted successfully using up the bandwidth share of the innocent nodes that follow the protocol standards. We obtained the theoretical network throughput by solving two-dimensional Markov Chain model as described by Bianchi [2], and Liu and Saadawi [3] to determine the channel capacity. We validated the results obtained via the theoretical computations with the results obtained by OPNET simulator [4] to define the baseline for the average attainable throughput in the channel under standard conditions where all nodes follow the standards. The main goal of the DoS attacker is to prevent the innocent nodes from accessing the channel and by capturing the channel’s bandwidth. In addition, the attacker strives to appear as an innocent node that follows the standards. The protocol resides in every node to enable each node to police other nodes in its immediate wireless coverage area. All innocent nodes are able to detect and identify the DoS attacker in its wireless coverage area. We applied the protocol to two Physical Layer technologies: Direct Sequence Spread Spectrum (DSSS) and Frequency Hopping Spread Spectrum (FHSS) and the results are presented to validate the algorithm. PMID:25685510

  6. DoS detection in IEEE 802.11 with the presence of hidden nodes.

    PubMed

    Soryal, Joseph; Liu, Xijie; Saadawi, Tarek

    2014-07-01

    The paper presents a novel technique to detect Denial of Service (DoS) attacks applied by misbehaving nodes in wireless networks with the presence of hidden nodes employing the widely used IEEE 802.11 Distributed Coordination Function (DCF) protocols described in the IEEE standard [1]. Attacker nodes alter the IEEE 802.11 DCF firmware to illicitly capture the channel via elevating the probability of the average number of packets transmitted successfully using up the bandwidth share of the innocent nodes that follow the protocol standards. We obtained the theoretical network throughput by solving two-dimensional Markov Chain model as described by Bianchi [2], and Liu and Saadawi [3] to determine the channel capacity. We validated the results obtained via the theoretical computations with the results obtained by OPNET simulator [4] to define the baseline for the average attainable throughput in the channel under standard conditions where all nodes follow the standards. The main goal of the DoS attacker is to prevent the innocent nodes from accessing the channel and by capturing the channel's bandwidth. In addition, the attacker strives to appear as an innocent node that follows the standards. The protocol resides in every node to enable each node to police other nodes in its immediate wireless coverage area. All innocent nodes are able to detect and identify the DoS attacker in its wireless coverage area. We applied the protocol to two Physical Layer technologies: Direct Sequence Spread Spectrum (DSSS) and Frequency Hopping Spread Spectrum (FHSS) and the results are presented to validate the algorithm.

  7. Methods for Identifying Object Class, Type, and Orientation in the Presence of Uncertainty

    DTIC Science & Technology

    1990-08-01

    on Range Finding Techniques for Computer Vision," IEEE Trans. on Pattern Analysis and Machine Intellegence PAMI-5 (2), pp 129-139 March 1983. 15. Yang... Artificial Intelligence Applications, pp 199-205, December 1984. 16. Flynn, P.J. and Jain, A.K.," On Reliable Curvature Estimation, " Proceedings of the

  8. Fast Electromagnetic Solvers for Large-Scale Naval Scattering Problems

    DTIC Science & Technology

    2008-09-27

    IEEE Trans. Antennas Propag., vol. 52, no. 8, pp. 2141–2146, 2004. [12] R. J. Burkholder and J. F. Lee, “Fast dual-MGS block-factorization algorithm...Golub and C. F. V. Loan, Matrix Computations. Baltimore: The Johns Hopkins University Press, 1996. [20] W. D. Li, W. Hong, and H. X. Zhou, “Integral

  9. Profile and Instrumentation Driven Methods for Embedded Signal Processing

    DTIC Science & Technology

    2015-01-01

    applications,” Computers, IEEE Transactions on, vol. 37, no. 9, pp. 1088–1098, Sep 1988. [7] Massimo Ravasi and Marco Mattavelli, “High-level algorithmic...profiling,” in Digital Media and its Application in Museum Heritages, Second Workshop on, Dec 2007, pp. 353–358. [15] H. Hubert , B. Stabernack, and K.-I. Wels

  10. Experimental validation of a predicted feedback loop in the multi-oscillator clock of Arabidopsis thaliana

    PubMed Central

    Locke, James C W; Kozma-Bognár, László; Gould, Peter D; Fehér, Balázs; Kevei, Éva; Nagy, Ferenc; Turner, Matthew S; Hall, Anthony; Millar, Andrew J

    2006-01-01

    Our computational model of the circadian clock comprised the feedback loop between LATE ELONGATED HYPOCOTYL (LHY), CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) and TIMING OF CAB EXPRESSION 1 (TOC1), and a predicted, interlocking feedback loop involving TOC1 and a hypothetical component Y. Experiments based on model predictions suggested GIGANTEA (GI) as a candidate for Y. We now extend the model to include a recently demonstrated feedback loop between the TOC1 homologues PSEUDO-RESPONSE REGULATOR 7 (PRR7), PRR9 and LHY and CCA1. This three-loop network explains the rhythmic phenotype of toc1 mutant alleles. Model predictions fit closely to new data on the gi;lhy;cca1 mutant, which confirm that GI is a major contributor to Y function. Analysis of the three-loop network suggests that the plant clock consists of morning and evening oscillators, coupled intracellularly, which may be analogous to coupled, morning and evening clock cells in Drosophila and the mouse. PMID:17102804

  11. Evolution of imaging for abdominal perforation

    PubMed Central

    Singh, JP; Steward, MJ; Booth, TC; Mukhtar, H; Murray, D

    2010-01-01

    INTRODUCTION Gastrointestinal (GI) perforation is a common surgical presentation. In recent years, computed tomography (CT) has been shown to be accurate for predicting the site of GI perforation, and has become the investigation of choice. However the signs may be subtle or only indirectly related to the site or aetiology of perforation. SUBJECTS AND METHODS A MEDLINE and PubMed search was performed for journals before June 2009 with MeSH major terms ‘CT’ and ‘perforation’. Non-English speaking literature was excluded. RESULTS Examples of GI perforation of various aetiologies are reviewed (inflammatory, neoplastic, traumatic and iatrogenic) high-lighting characteristic CT appearances as well as pitfalls in diagnosis. Features of perforation include the presence of free gas or fluid within the supra- and/or inframesocolic compartments, segmental bowel wall thickening, bowel wall discontinuity, stranding of the mesenteric fat and abscess formation. CONCLUSIONS These differentiating features facilitate accurate multidisciplinary pre-operative evaluation, necessary to plan patient management and potential surgical approach. PMID:20412668

  12. Learning directed acyclic graphs from large-scale genomics data.

    PubMed

    Nikolay, Fabio; Pesavento, Marius; Kritikos, George; Typas, Nassos

    2017-09-20

    In this paper, we consider the problem of learning the genetic interaction map, i.e., the topology of a directed acyclic graph (DAG) of genetic interactions from noisy double-knockout (DK) data. Based on a set of well-established biological interaction models, we detect and classify the interactions between genes. We propose a novel linear integer optimization program called the Genetic-Interactions-Detector (GENIE) to identify the complex biological dependencies among genes and to compute the DAG topology that matches the DK measurements best. Furthermore, we extend the GENIE program by incorporating genetic interaction profile (GI-profile) data to further enhance the detection performance. In addition, we propose a sequential scalability technique for large sets of genes under study, in order to provide statistically significant results for real measurement data. Finally, we show via numeric simulations that the GENIE program and the GI-profile data extended GENIE (GI-GENIE) program clearly outperform the conventional techniques and present real data results for our proposed sequential scalability technique.

  13. Magnetorotational instability and dynamo action in gravito-turbulent astrophysical discs

    NASA Astrophysics Data System (ADS)

    Riols, A.; Latter, H.

    2018-02-01

    Though usually treated in isolation, the magnetorotational and gravitational instabilities (MRI and GI) may coincide at certain radii and evolutionary stages of protoplanetary discs and active galactic nuclei. Their mutual interactions could profoundly influence several important processes, such as accretion variability and outbursts, fragmentation and disc truncation, or large-scale magnetic field production. Direct numerical simulations of both instabilities are computationally challenging and remain relatively unexplored. In this paper, we aim to redress this neglect via a set of 3D vertically stratified shearing-box simulations, combining self-gravity and magnetic fields. We show that gravito-turbulence greatly weakens the zero-net-flux MRI. In the limit of efficient cooling (and thus enhanced GI), the MRI is completely suppressed, and yet strong magnetic fields are sustained by the gravito-turbulence. This turbulent `spiral wave' dynamo may have widespread application, especially in galactic discs. Finally, we present preliminary work showing that a strong net-vertical-flux revives the MRI and supports a magnetically dominated state in which the GI is secondary.

  14. Optical image transformation and encryption by phase-retrieval-based double random-phase encoding and compressive ghost imaging

    NASA Astrophysics Data System (ADS)

    Yuan, Sheng; Yang, Yangrui; Liu, Xuemei; Zhou, Xin; Wei, Zhenzhuo

    2018-01-01

    An optical image transformation and encryption scheme is proposed based on double random-phase encoding (DRPE) and compressive ghost imaging (CGI) techniques. In this scheme, a secret image is first transformed into a binary image with the phase-retrieval-based DRPE technique, and then encoded by a series of random amplitude patterns according to the ghost imaging (GI) principle. Compressive sensing, corrosion and expansion operations are implemented to retrieve the secret image in the decryption process. This encryption scheme takes the advantage of complementary capabilities offered by the phase-retrieval-based DRPE and GI-based encryption techniques. That is the phase-retrieval-based DRPE is used to overcome the blurring defect of the decrypted image in the GI-based encryption, and the CGI not only reduces the data amount of the ciphertext, but also enhances the security of DRPE. Computer simulation results are presented to verify the performance of the proposed encryption scheme.

  15. Microbial genomic island discovery, visualization and analysis.

    PubMed

    Bertelli, Claire; Tilley, Keith E; Brinkman, Fiona S L

    2018-06-03

    Horizontal gene transfer (also called lateral gene transfer) is a major mechanism for microbial genome evolution, enabling rapid adaptation and survival in specific niches. Genomic islands (GIs), commonly defined as clusters of bacterial or archaeal genes of probable horizontal origin, are of particular medical, environmental and/or industrial interest, as they disproportionately encode virulence factors and some antimicrobial resistance genes and may harbor entire metabolic pathways that confer a specific adaptation (solvent resistance, symbiosis properties, etc). As large-scale analyses of microbial genomes increases, such as for genomic epidemiology investigations of infectious disease outbreaks in public health, there is increased appreciation of the need to accurately predict and track GIs. Over the past decade, numerous computational tools have been developed to tackle the challenges inherent in accurate GI prediction. We review here the main types of GI prediction methods and discuss their advantages and limitations for a routine analysis of microbial genomes in this era of rapid whole-genome sequencing. An assessment is provided of 20 GI prediction software methods that use sequence-composition bias to identify the GIs, using a reference GI data set from 104 genomes obtained using an independent comparative genomics approach. Finally, we present guidelines to assist researchers in effectively identifying these key genomic regions.

  16. Ambiguity Function Analysis for UMTS-Based Passive Multistatic Radar

    DTIC Science & Technology

    2014-04-16

    Sandeep Gogineni, Member, IEEE, Muralidhar Rangaswamy, Fellow, IEEE, Brian D . Rigling, Senior Member, IEEE, and Arye Nehorai, Fellow, IEEE Abstract—There...muralidhar.rangaswamy@us.af. mil). B. D . Rigling is with the Department of Electrical Engineering, Wright State University, Dayton, OH 45435 USA (e-mail...ieeexplore.ieee.org. Digital Object Identifier 10.1109/TSP.2014.2318135 [1]–[9] and audio broadcast signals and FM radio [10], [11], satellite-based [12], and

  17. Delay Analysis of GTS Bridging between IEEE 802.15.4 and IEEE 802.11 Networks for Healthcare Applications

    PubMed Central

    Mišić, Jelena; (Sherman) Shen, Xuemin

    2009-01-01

    We consider interconnection of IEEE 802.15.4 beacon-enabled network cluster with IEEE 802.11b network. This scenario is important in healthcare applications where IEEE 802.15.4 nodes comprise patient's body area network (BAN) and are involved in sensing some health-related data. BAN nodes have very short communication range in order to avoid harming patient's health and save energy. Sensed data needs to be transmitted to an access point in the ward room using wireless technology with higher transmission range and rate such as IEEE 802.11b. We model the interconnected network where IEEE 802.15.4-based BAN operates in guaranteed time slot (GTS) mode, and IEEE 802.11b part of the bridge conveys GTS superframe to the 802.11b access point. We then analyze the network delays. Performance analysis is performed using EKG traffic from continuous telemetry, and we discuss the delays of communication due the increasing number of patients. PMID:19107184

  18. IEEE 802.11ah: A Technology to Face the IoT Challenge.

    PubMed

    Baños-Gonzalez, Victor; Afaqui, M Shahwaiz; Lopez-Aguilera, Elena; Garcia-Villegas, Eduard

    2016-11-22

    Since the conception of the Internet of things (IoT), a large number of promising applications and technologies have been developed, which will change different aspects in our daily life. This paper explores the key characteristics of the forthcoming IEEE 802.11ah specification. This future IEEE 802.11 standard aims to amend the IEEE 802.11 legacy specification to support IoT requirements. We present a thorough evaluation of the foregoing amendment in comparison to the most notable IEEE 802.11 standards. In addition, we expose the capabilities of future IEEE 802.11ah in supporting different IoT applications. Also, we provide a brief overview of the technology contenders that are competing to cover the IoT communications framework. Numerical results are presented showing how the future IEEE 802.11ah specification offers the features required by IoT communications, thus putting forward IEEE 802.11ah as a technology to cater the needs of the Internet of Things paradigm.

  19. IEEE 802.11ah: A Technology to Face the IoT Challenge

    PubMed Central

    Baños-Gonzalez, Victor; Afaqui, M. Shahwaiz; Lopez-Aguilera, Elena; Garcia-Villegas, Eduard

    2016-01-01

    Since the conception of the Internet of things (IoT), a large number of promising applications and technologies have been developed, which will change different aspects in our daily life. This paper explores the key characteristics of the forthcoming IEEE 802.11ah specification. This future IEEE 802.11 standard aims to amend the IEEE 802.11 legacy specification to support IoT requirements. We present a thorough evaluation of the foregoing amendment in comparison to the most notable IEEE 802.11 standards. In addition, we expose the capabilities of future IEEE 802.11ah in supporting different IoT applications. Also, we provide a brief overview of the technology contenders that are competing to cover the IoT communications framework. Numerical results are presented showing how the future IEEE 802.11ah specification offers the features required by IoT communications, thus putting forward IEEE 802.11ah as a technology to cater the needs of the Internet of Things paradigm. PMID:27879688

  20. Delay Analysis of GTS Bridging between IEEE 802.15.4 and IEEE 802.11 Networks for Healthcare Applications.

    PubMed

    Misić, Jelena; Sherman Shen, Xuemin

    2009-01-01

    We consider interconnection of IEEE 802.15.4 beacon-enabled network cluster with IEEE 802.11b network. This scenario is important in healthcare applications where IEEE 802.15.4 nodes comprise patient's body area network (BAN) and are involved in sensing some health-related data. BAN nodes have very short communication range in order to avoid harming patient's health and save energy. Sensed data needs to be transmitted to an access point in the ward room using wireless technology with higher transmission range and rate such as IEEE 802.11b. We model the interconnected network where IEEE 802.15.4-based BAN operates in guaranteed time slot (GTS) mode, and IEEE 802.11b part of the bridge conveys GTS superframe to the 802.11b access point. We then analyze the network delays. Performance analysis is performed using EKG traffic from continuous telemetry, and we discuss the delays of communication due the increasing number of patients.

  1. Electrical stimulation of gut motility guided by an in silico model

    NASA Astrophysics Data System (ADS)

    Barth, Bradley B.; Henriquez, Craig S.; Grill, Warren M.; Shen, Xiling

    2017-12-01

    Objective. Neuromodulation of the central and peripheral nervous systems is becoming increasingly important for treating a diverse set of diseases—ranging from Parkinson’s Disease and epilepsy to chronic pain. However, neuromodulation of the gastrointestinal (GI) tract has achieved relatively limited success in treating functional GI disorders, which affect a significant population, because the effects of stimulation on the enteric nervous system (ENS) and gut motility are not well understood. Here we develop an integrated neuromechanical model of the ENS and assess neurostimulation strategies for enhancing gut motility, validated by in vivo experiments. Approach. The computational model included a network of enteric neurons, smooth muscle fibers, and interstitial cells of Cajal, which regulated propulsion of a virtual pellet in a model of gut motility. Main results. Simulated extracellular stimulation of ENS-mediated motility revealed that sinusoidal current at 0.5 Hz was more effective at increasing intrinsic peristalsis and reducing colon transit time than conventional higher frequency rectangular current pulses, as commonly used for neuromodulation therapy. Further analysis of the model revealed that the 0.5 Hz sinusoidal currents were more effective at modulating the pacemaker frequency of interstitial cells of Cajal. To test the predictions of the model, we conducted in vivo electrical stimulation of the distal colon while measuring bead propulsion in awake rats. Experimental results confirmed that 0.5 Hz sinusoidal currents were more effective than higher frequency pulses at enhancing gut motility. Significance. This work demonstrates an in silico GI neuromuscular model to enable GI neuromodulation parameter optimization and suggests that low frequency sinusoidal currents may improve the efficacy of GI pacing.

  2. Information Transfer Ion Wireless Networks

    DTIC Science & Technology

    2010-07-01

    conferences with proceed- ings to be made available online in the IEEE Xplore database, namely IFIP Wireless Days (WD 2008) at Dubai, UAE, and the...Poland, May 2008, pp. 61-64, IEEE Xplore , DOI = 10.1109/INFTECH. 2008.4621591. 2. J. Konorski, IEEE 802.11 LAN Capacity: Incentives and Incentive...2008, Dubai, UAE, Nov. 2008, IEEE Xplore DOI = 10.1109/WD.2008.4812857. 4. J. Konorski, QoS Provision in an Ad Hoc IEEE 802.11 WLAN: A Bayesian War

  3. Information Transfer in Wireless Networks

    DTIC Science & Technology

    2010-07-01

    conferences with proceed- ings to be made available online in the IEEE Xplore database, namely IFIP Wireless Days (WD 2008) at Dubai, UAE, and the...Poland, May 2008, pp. 61-64, IEEE Xplore , DOI = 10.1109/INFTECH. 2008.4621591. 2. J. Konorski, IEEE 802.11 LAN Capacity: Incentives and Incentive...2008, Dubai, UAE, Nov. 2008, IEEE Xplore DOI = 10.1109/WD.2008.4812857. 4. J. Konorski, QoS Provision in an Ad Hoc IEEE 802.11 WLAN: A Bayesian War

  4. The Practical Impact of Recent Computer Advances on the Analysis and Design of Large Scale Networks

    DTIC Science & Technology

    1974-12-01

    Communications, ICC-74, June 17-19, Minneapolis, Minnesota, pp. 31C-1-21C-5. 28. Gitman , I., R, M. Van Slvke and H. Frank, "On Splitting Random Access Broadcast...1974. 29. Gitman , I., "On the Capacity of Slotted ALOHA Network and Some Design Problems," IEEE Transactions on Communications, Maren, 1975. 30

  5. Designing Robust and Resilient Tactical MANETs

    DTIC Science & Technology

    2014-09-25

    Bounds on the Throughput Efficiency of Greedy Maximal Scheduling in Wireless Networks , IEEE/ACM Transactions on Networking , (06 2011): 0. doi: N... Wireless Sensor Networks and Effects of Long Range Dependant Data, Special IWSM Issue of Sequential Analysis, (11 2012): 0. doi: A. D. Dominguez...Bushnell, R. Poovendran. A Convex Optimization Approach for Clone Detection in Wireless Sensor Networks , Pervasive and Mobile Computing, (01 2012

  6. Performance Analysis of the Mobile IP Protocol (RFC 3344 and Related RFCS)

    DTIC Science & Technology

    2006-12-01

    Encapsulation HMAC Keyed-Hash Message Authentication Code ICMP Internet Control Message Protocol IEEE Institute of Electrical and Electronics Engineers IETF...Internet Engineering Task Force IOS Internetwork Operating System IP Internet Protocol ITU International Telecommunication Union LAN Local Area...network computing. Most organizations today have sophisticated networks that are connected to the Internet. The major benefit reaped from such a

  7. Projector-Camera Systems for Immersive Training

    DTIC Science & Technology

    2006-01-01

    average to a sequence of 100 captured distortion corrected images. The OpenCV library [ OpenCV ] was used for camera calibration. To correct for...rendering application [Treskunov, Pair, and Swartout, 2004]. It was transposed to take into account different matrix conventions between OpenCV and...Screen Imperfections. Proc. Workshop on Projector-Camera Systems (PROCAMS), Nice, France, IEEE. OpenCV : Open Source Computer Vision. [Available

  8. Sparse Matrix Motivated Reconstruction of Far-Field Radiation Patterns

    DTIC Science & Technology

    2015-03-01

    method for base - station antenna radiation patterns. IEEE Antennas Propagation Magazine. 2001;43(2):132. 4. Vasiliadis TG, Dimitriou D, Sergiadis JD...algorithm based on sparse representations of radiation patterns using the inverse Discrete Fourier Transform (DFT) and the inverse Discrete Cosine...patterns using a Model- Based Parameter Estimation (MBPE) technique that reduces the computational time required to model radiation patterns. Another

  9. Using Artificial Physics to Control Agents

    DTIC Science & Technology

    1999-11-01

    unlimited 13. SUPPLEMENTARY NOTES IEEE International Conference on Information, Intelligence, and Systems, Oct 31 -Nov 3,1999. Bethesda, MD 14. ABSTRACT...distributed control can also perform distributed computation. 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT Same...1995. [9] H. Pattee. Artificial life needs a real epistemology. In Moran, Moreno, Merelo, and Chacon , editors, Advances in Artificial Life, pages

  10. IEEE Standards activities: A year in review. Annual activities report 1996

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1997-09-01

    For IEEE Standards and the constituency it serves, 1996 was a milestone year. It was a period that signaled the beginning of the Standards Program of the future. This program responds to worldwide standards issues and to the technical, market and competitive strategies of industrial sectors. It represents technological innovation, global participation in electrotechnology standards development and dedication to the on-going advancement and promotion of new concepts and technology. Instrumental in ensuring IEEE`s growth opportunities and leadership position in electrotechnology standards development and dissemination is IEEE membership. The value of members and their involvement in IEEE Standards is vital tomore » IEEE`s ability to continuously be the best professional association in the world. To fulfill this vision, IEEE set forth five goals -- increased globalization, career enhancement, electronic dissemination of existing products and services, organizational improvements and public responsibility. Key in the process for the achievement of these goals is to make certain that IEEE members are well informed about opportunities and benefits the present system of standardization offers, and what the future system will offer. With the member in mind, the Standards Board reviewed its strategic direction and operational structures, and its ability to deliver products and services that are needed now and, more importantly, that will be needed in the future. This Annual Activities Report provides a comprehensive picture of 1996 accomplishments and performance. It gives readers a broad picture of the Standards Board`s activities, the evolving role of IEEE Standards and the technological opportunities that the Board encourages.« less

  11. Biomedical, Artificial Intelligence, and DNA Computing Photonics Applications and Web Engineering, Wilga, May 2012

    NASA Astrophysics Data System (ADS)

    Romaniuk, Ryszard S.

    2012-05-01

    This paper is the fifth part (out of five) of the research survey of WILGA Symposium work, May 2012 Edition, concerned with Biomedical, Artificial Intelligence and DNA Computing technologies. It presents a digest of chosen technical work results shown by young researchers from different technical universities from this country during the Jubilee XXXth SPIE-IEEE Wilga 2012, May Edition, symposium on Photonics and Web Engineering. Topical tracks of the symposium embraced, among others, nanomaterials and nanotechnologies for photonics, sensory and nonlinear optical fibers, object oriented design of hardware, photonic metrology, optoelectronics and photonics applications, photonics-electronics co-design, optoelectronic and electronic systems for astronomy and high energy physics experiments, JET tokamak and pi-of-the sky experiments development. The symposium is an annual summary in the development of numerable Ph.D. theses carried out in this country in the area of advanced electronic and photonic systems. It is also a great occasion for SPIE, IEEE, OSA and PSP students to meet together in a large group spanning the whole country with guests from this part of Europe. A digest of Wilga references is presented [1-270].

  12. Virtualized Traffic: reconstructing traffic flows from discrete spatiotemporal data.

    PubMed

    Sewall, Jason; van den Berg, Jur; Lin, Ming C; Manocha, Dinesh

    2011-01-01

    We present a novel concept, Virtualized Traffic, to reconstruct and visualize continuous traffic flows from discrete spatiotemporal data provided by traffic sensors or generated artificially to enhance a sense of immersion in a dynamic virtual world. Given the positions of each car at two recorded locations on a highway and the corresponding time instances, our approach can reconstruct the traffic flows (i.e., the dynamic motions of multiple cars over time) between the two locations along the highway for immersive visualization of virtual cities or other environments. Our algorithm is applicable to high-density traffic on highways with an arbitrary number of lanes and takes into account the geometric, kinematic, and dynamic constraints on the cars. Our method reconstructs the car motion that automatically minimizes the number of lane changes, respects safety distance to other cars, and computes the acceleration necessary to obtain a smooth traffic flow subject to the given constraints. Furthermore, our framework can process a continuous stream of input data in real time, enabling the users to view virtualized traffic events in a virtual world as they occur. We demonstrate our reconstruction technique with both synthetic and real-world input. © 2011 IEEE Published by the IEEE Computer Society

  13. Throughput analysis of the IEEE 802.4 token bus standard under heavy load

    NASA Technical Reports Server (NTRS)

    Pang, Joseph; Tobagi, Fouad

    1987-01-01

    It has become clear in the last few years that there is a trend towards integrated digital services. Parallel to the development of public Integrated Services Digital Network (ISDN) is service integration in the local area (e.g., a campus, a building, an aircraft). The types of services to be integrated depend very much on the specific local environment. However, applications tend to generate data traffic belonging to one of two classes. According to IEEE 802.4 terminology, the first major class of traffic is termed synchronous, such as packetized voice and data generated from other applications with real-time constraints, and the second class is called asynchronous which includes most computer data traffic such as file transfer or facsimile. The IEEE 802.4 token bus protocol which was designed to support both synchronous and asynchronous traffic is examined. The protocol is basically a timer-controlled token bus access scheme. By a suitable choice of the design parameters, it can be shown that access delay is bounded for synchronous traffic. As well, the bandwidth allocated to asynchronous traffic can be controlled. A throughput analysis of the protocol under heavy load with constant channel occupation of synchronous traffic and constant token-passing times is presented.

  14. Versatile, low-cost, computer-controlled, sample positioning system for vacuum applications

    NASA Technical Reports Server (NTRS)

    Vargas-Aburto, Carlos; Liff, Dale R.

    1991-01-01

    A versatile, low-cost, easy to implement, microprocessor-based motorized positioning system (MPS) suitable for accurate sample manipulation in a Second Ion Mass Spectrometry (SIMS) system, and for other ultra-high vacuum (UHV) applications was designed and built at NASA LeRC. The system can be operated manually or under computer control. In the latter case, local, as well as remote operation is possible via the IEEE-488 bus. The position of the sample can be controlled in three linear orthogonal and one angular coordinates.

  15. 10 CFR 431.447 - Department of Energy recognition of nationally recognized certification programs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... IEEE Std 112-2004 Test Methods A and B, IEEE Std 114-2010, CSA C390-10, and CSA C747 (incorporated by... IEEE Std 112-2004 Test Methods A and B, IEEE Std 114-2010, CSA C390-10, and CSA C747- (incorporated by...

  16. 10 CFR 431.447 - Department of Energy recognition of nationally recognized certification programs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... IEEE Std 112-2004 Test Methods A and B, IEEE Std 114-2010, CSA C390-10, and CSA C747 (incorporated by... IEEE Std 112-2004 Test Methods A and B, IEEE Std 114-2010, CSA C390-10, and CSA C747- (incorporated by...

  17. IEEE Std 730 Software Quality Assurance: Supporting CMMI-DEV v1.3, Product and Process Quality Assurance

    DTIC Science & Technology

    2011-05-27

    frameworks 4 CMMI-DEV IEEE / ISO / IEC 15288 / 12207 Quality Assurance ©2011 Walz IEEE Life Cycle Processes & Artifacts • Systems Life Cycle Processes...TAG to ISO TC 176 Quality Management • Quality: ASQ, work experience • Software: three books, consulting, work experience • Systems: Telecom & DoD...and IEEE 730 SQA need to align. The P730 IEEE standards working group has expanded the scope of the SQA process standard to align with IS 12207

  18. GreenView and GreenLand Applications Development on SEE-GRID Infrastructure

    NASA Astrophysics Data System (ADS)

    Mihon, Danut; Bacu, Victor; Gorgan, Dorian; Mészáros, Róbert; Gelybó, Györgyi; Stefanut, Teodor

    2010-05-01

    The GreenView and GreenLand applications [1] have been developed through the SEE-GRID-SCI (SEE-GRID eInfrastructure for regional eScience) FP7 project co-funded by the European Commission [2]. The development of environment applications is a challenge for Grid technologies and software development methodologies. This presentation exemplifies the development of the GreenView and GreenLand applications over the SEE-GRID infrastructure by the Grid Application Development Methodology [3]. Today's environmental applications are used in vary domains of Earth Science such as meteorology, ground and atmospheric pollution, ground metal detection or weather prediction. These applications run on satellite images (e.g. Landsat, MERIS, MODIS, etc.) and the accuracy of output results depends mostly of the quality of these images. The main drawback of such environmental applications regards the need of computation power and storage power (some images are almost 1GB in size), in order to process such a large data volume. Actually, almost applications requiring high computation resources have approached the migration onto the Grid infrastructure. This infrastructure offers the computing power by running the atomic application components on different Grid nodes in sequential or parallel mode. The middleware used between the Grid infrastructure and client applications is ESIP (Environment Oriented Satellite Image Processing Platform), which is based on gProcess platform [4]. In its current format, gProcess is used for launching new processes on the Grid nodes, but also for monitoring the execution status of these processes. This presentation highlights two case studies of Grid based environmental applications, GreenView and GreenLand [5]. GreenView is used in correlation with MODIS (Moderate Resolution Imaging Spectroradiometer) satellite images and meteorological datasets, in order to produce pseudo colored temperature and vegetation maps for different geographical CEE (Central Eastern Europe) regions. On the other hand, GreenLand is used for generating maps for different vegetation indexes (e.g. NDVI, EVI, SAVI, GEMI) based on Landsat satellite images. Both applications are using interpolation and random value generation algorithms, but also specific formulas for computing vegetation index values. The GreenView and GreenLand applications have been experimented over the SEE-GRID infrastructure and the performance evaluation is reported in [6]. The improvement of the execution time (obtained through a better parallelization of jobs), the extension of geographical areas to other parts of the Earth, and new user interaction techniques on spatial data and large set of satellite images are the goals of the future work. References [1] GreenView application on Wiki, http://wiki.egee-see.org/index.php/GreenView [2] SEE-GRID-SCI Project, http://www.see-grid-sci.eu/ [3] Gorgan D., Stefanut T., Bâcu V., Mihon D., Grid based Environment Application Development Methodology, SCICOM, 7th International Conference on "Large-Scale Scientific Computations", 4-8 June, 2009, Sozopol, Bulgaria, (To be published by Springer), (2009). [4] Gorgan D., Bacu V., Stefanut T., Rodila D., Mihon D., Grid based Satellite Image Processing Platform for Earth Observation Applications Development. IDAACS'2009 - IEEE Fifth International Workshop on "Intelligent Data Acquisition and Advanced Computing Systems: Technology and Applications", 21-23 September, Cosenza, Italy, IEEE Published in Computer Press, 247-252 (2009). [5] Mihon D., Bacu V., Stefanut T., Gorgan D., "Grid Based Environment Application Development - GreenView Application". ICCP2009 - IEEE 5th International Conference on Intelligent Computer Communication and Processing, 27 Aug, 2009 Cluj-Napoca. Published by IEEE Computer Press, pp. 275-282 (2009). [6] Danut Mihon, Victor Bacu, Dorian Gorgan, Róbert Mészáros, Györgyi Gelybó, Teodor Stefanut, Practical Considerations on the GreenView Application Development and Execution over SEE-GRID. SEE-GRID-SCI User Forum, 9-10 Dec 2009, Bogazici University, Istanbul, Turkey, ISBN: 978-975-403-510-0, pp. 167-175 (2009).

  19. Designing Green Stormwater Infrastructure for Hydrologic and Human Benefits: An Image Based Machine Learning Approach

    NASA Astrophysics Data System (ADS)

    Rai, A.; Minsker, B. S.

    2014-12-01

    Urbanization over the last century has degraded our natural water resources by increasing storm-water runoff, reducing nutrient retention, and creating poor ecosystem health downstream. The loss of tree canopy and expansion of impervious area and storm sewer systems have significantly decreased infiltration and evapotranspiration, increased stream-flow velocities, and increased flood risk. These problems have brought increasing attention to catchment-wide implementation of green infrastructure (e.g., decentralized green storm water management practices such as bioswales, rain gardens, permeable pavements, tree box filters, cisterns, urban wetlands, urban forests, stream buffers, and green roofs) to replace or supplement conventional storm water management practices and create more sustainable urban water systems. Current green infrastructure (GI) practice aims at mitigating the negative effects of urbanization by restoring pre-development hydrology and ultimately addressing water quality issues at an urban catchment scale. The benefits of green infrastructure extend well beyond local storm water management, as urban green spaces are also major contributors to human health. Considerable research in the psychological sciences have shown significant human health benefits from appropriately designed green spaces, yet impacts on human wellbeing have not yet been formally considered in GI design frameworks. This research is developing a novel computational green infrastructure (GI) design framework that integrates hydrologic requirements with criteria for human wellbeing. A supervised machine learning model is created to identify specific patterns in urban green spaces that promote human wellbeing; the model is linked to RHESSYS model to evaluate GI designs in terms of both hydrologic and human health benefits. An application of the models to Dead Run Watershed in Baltimore showed that image mining methods were able to capture key elements of human preferences that could improve tree-based GI design. Hydrologic benefits associated with these features were substantial, indicating that increased urban tree coverage and a more integrated GI design approach can significantly increase both human and hydrologic benefits.

  20. Comparison and Analysis of ISO/IEEE 11073, IHE PCD-01, and HL7 FHIR Messages for Personal Health Devices

    PubMed Central

    Do, Hyoungho

    2018-01-01

    Objectives Increasing use of medical devices outside of healthcare facilities inevitably requires connectivity and interoperability between medical devices and healthcare information systems. To this end, standards have been developed and used to provide interoperability between personal health devices (PHDs) and external systems. ISO/IEEE 11073 standards and IHE PCD-01 standard messages have been used the most in the exchange of observation data of health devices. Recently, transmitting observation data using the HL7 FHIR standard has been devised in the name of DoF (Devices on FHIR) and adopted very fast. We compare and analyze these standards and suggest that which standard will work best at the different environments of device usage. Methods We generated each message/resource of the three standards for observed vital signs from blood pressure monitor and thermometer. Then, the size, the contents, and the exchange processes of these messages are compared and analyzed. Results ISO/IEEE 11073 standard message has the smallest data size, but it has no ability to contain the key information, patient information. On the other hand, PCD-01 messages and FHIR standards have the fields for patient information. HL7 DoF standards provide reusing of information unit known as resource, and it is relatively easy to parse DoF messages since it uses widely known XML and JSON. Conclusions ISO/IEEE 11073 standards are suitable for devices having very small computing power. IHE PCD-01 and HL7 DoF messages can be used for the devices that need to be connected to hospital information systems that require patient information. When information reuse is frequent, DoF is advantageous over PCD-01. PMID:29503752

  1. Comparison and Analysis of ISO/IEEE 11073, IHE PCD-01, and HL7 FHIR Messages for Personal Health Devices.

    PubMed

    Lee, Sungkee; Do, Hyoungho

    2018-01-01

    Increasing use of medical devices outside of healthcare facilities inevitably requires connectivity and interoperability between medical devices and healthcare information systems. To this end, standards have been developed and used to provide interoperability between personal health devices (PHDs) and external systems. ISO/IEEE 11073 standards and IHE PCD-01 standard messages have been used the most in the exchange of observation data of health devices. Recently, transmitting observation data using the HL7 FHIR standard has been devised in the name of DoF (Devices on FHIR) and adopted very fast. We compare and analyze these standards and suggest that which standard will work best at the different environments of device usage. We generated each message/resource of the three standards for observed vital signs from blood pressure monitor and thermometer. Then, the size, the contents, and the exchange processes of these messages are compared and analyzed. ISO/IEEE 11073 standard message has the smallest data size, but it has no ability to contain the key information, patient information. On the other hand, PCD-01 messages and FHIR standards have the fields for patient information. HL7 DoF standards provide reusing of information unit known as resource, and it is relatively easy to parse DoF messages since it uses widely known XML and JSON. ISO/IEEE 11073 standards are suitable for devices having very small computing power. IHE PCD-01 and HL7 DoF messages can be used for the devices that need to be connected to hospital information systems that require patient information. When information reuse is frequent, DoF is advantageous over PCD-01.

  2. Automotive Research Center

    Science.gov Websites

    7, 2018, LA Times) Dr. Jason Siegel to chair IEEE Technical Committee on Automotive Controls (Feb 2018, IEEE) Dr. Anna Stefanopoulou on research of sustainable vehicle technologies (Jan 24, 2018, WEMU ) Stefanopoulou plenary at IEEE 56th CDC (Jan 17, 2018, ME) ARC Researchers at IEEE 56th Conf. Decision and

  3. ARC Events

    Science.gov Websites

    chair IEEE Technical Committee on Automotive Controls (Feb 2018, IEEE) Dr. Anna Stefanopoulou on research of sustainable vehicle technologies (Jan 24, 2018, WEMU) Stefanopoulou plenary at IEEE 56th CDC (Jan 17, 2018, ME) ARC Researchers at IEEE 56th Conf. Decision and Control (Dec 12-14, 2017, CDC) ARC

  4. Invisible watermarking optical camera communication and compatibility issues of IEEE 802.15.7r1 specification

    NASA Astrophysics Data System (ADS)

    Le, Nam-Tuan

    2017-05-01

    Copyright protection and information security are two most considered issues of digital data following the development of internet and computer network. As an important solution for protection, watermarking technology has become one of the challenged roles in industry and academic research. The watermarking technology can be classified by two categories: visible watermarking and invisible watermarking. With invisible technique, there is an advantage on user interaction because of the visibility. By applying watermarking for communication, it will be a challenge and a new direction for communication technology. In this paper we will propose one new research on communication technology using optical camera communications (OCC) based invisible watermarking. Beside the analysis on performance of proposed system, we also suggest the frame structure of PHY and MAC layer for IEEE 802.15.7r1 specification which is a revision of visible light communication (VLC) standardization.

  5. Phase II Trial of Combined High-Dose-Rate Brachytherapy and External Beam Radiotherapy for Adenocarcinoma of the Prostate: Preliminary Results of RTOG 0321

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hsu, I-Chow, E-mail: ihsu@radonc.ucsf.ed; Bae, Kyounghwa; Shinohara, Katsuto

    2010-11-01

    Purpose: To estimate the rate of late Grade 3 or greater genitourinary (GU) and gastrointestinal (GI) adverse events (AEs) after treatment with external beam radiotherapy and prostate high-dose-rate (HDR) brachytherapy. Methods and Materials: Each participating institution submitted computed tomography-based HDR brachytherapy dosimetry data electronically for credentialing and for each study patient. Patients with locally confined Stage T1c-T3b prostate cancer were eligible for the present study. All patients were treated with 45 Gy in 25 fractions using external beam radiotherapy and one HDR implant delivering 19 Gy in two fractions. All AEs were graded according to the Common Terminology Criteria formore » Adverse Events, version 3.0. Late GU/GI AEs were defined as those occurring >9 months from the start of the protocol treatment, in patients with {>=}18 months of potential follow-up. Results: A total of 129 patients from 14 institutions were enrolled in the present study. Of the 129 patients, 125 were eligible, and AE data were available for 112 patients at analysis. The pretreatment characteristics of the patients were as follows: Stage T1c-T2c, 91%; Stage T3a-T3b, 9%; prostate-specific antigen level {<=}10 ng/mL, 70%; prostate-specific antigen level >10 but {<=}20 ng/mL, 30%; and Gleason score 2-6, 10%; Gleason score 7, 72%; and Gleason score 8-10, 18%. At a median follow-up of 29.6 months, three acute and four late Grade 3 GU/GI AEs were reported. The estimated rate of late Grade 3-5 GU and GI AEs at 18 months was 2.56%. Conclusion: This is the first prospective, multi-institutional trial of computed tomography-based HDR brachytherapy and external beam radiotherapy. The technique and doses used in the present study resulted in acceptable levels of AEs.« less

  6. ACG Clinical Guideline: Diagnosis and Management of Small Bowel Bleeding.

    PubMed

    Gerson, Lauren B; Fidler, Jeff L; Cave, David R; Leighton, Jonathan A

    2015-09-01

    Bleeding from the small intestine remains a relatively uncommon event, accounting for ~5-10% of all patients presenting with gastrointestinal (GI) bleeding. Given advances in small bowel imaging with video capsule endoscopy (VCE), deep enteroscopy, and radiographic imaging, the cause of bleeding in the small bowel can now be identified in most patients. The term small bowel bleeding is therefore proposed as a replacement for the previous classification of obscure GI bleeding (OGIB). We recommend that the term OGIB should be reserved for patients in whom a source of bleeding cannot be identified anywhere in the GI tract. A source of small bowel bleeding should be considered in patients with GI bleeding after performance of a normal upper and lower endoscopic examination. Second-look examinations using upper endoscopy, push enteroscopy, and/or colonoscopy can be performed if indicated before small bowel evaluation. VCE should be considered a first-line procedure for small bowel investigation. Any method of deep enteroscopy can be used when endoscopic evaluation and therapy are required. VCE should be performed before deep enteroscopy if there is no contraindication. Computed tomographic enterography should be performed in patients with suspected obstruction before VCE or after negative VCE examinations. When there is acute overt hemorrhage in the unstable patient, angiography should be performed emergently. In patients with occult hemorrhage or stable patients with active overt bleeding, multiphasic computed tomography should be performed after VCE or CTE to identify the source of bleeding and to guide further management. If a source of bleeding is identified in the small bowel that is associated with significant ongoing anemia and/or active bleeding, the patient should be managed with endoscopic therapy. Conservative management is recommended for patients without a source found after small bowel investigation, whereas repeat diagnostic investigations are recommended for patients with initial negative small bowel evaluations and ongoing overt or occult bleeding.

  7. Adaptive, Tactical Mesh Networking: Control Base MANET Model

    DTIC Science & Technology

    2010-09-01

    pp. 316–320 Available: IEEE Xplore , http://ieeexplore.ieee.org [Accessed: June 9, 2010]. [5] N. Sidiropoulos, “Multiuser Transmit Beamforming...Mobile Mesh Segments of TNT Testbed .......... 11 Figure 5. Infrastructure and Ad Hoc Mode of IEEE 802.11................................ 13 Figure...6. The Power Spectral Density of OFDM................................................ 14 Figure 7. A Typical IEEE 802.16 Network

  8. Bleeding after expandable nitinol stent placement in patients with esophageal and upper gastrointestinal obstruction: incidence, management, and predictors.

    PubMed

    Oh, Se Jin; Song, Ho-Young; Nam, Deok Ho; Ko, Heung Kyu; Park, Jung-Hoon; Na, Han Kyu; Lee, Jong Jin; Kang, Min Kyoung

    2014-11-01

    Placement of self-expandable nitinol stents is useful for the treatment of esophageal and upper gastrointestinal (GI) obstruction. However, complications such as stent migration, tumor overgrowth, and bleeding occur. Although stent migration and tumor overgrowth are well documented in previous studies, the occurrence of bleeding has not been fully evaluated. To evaluate the incidence, management strategies, and predictors of bleeding after placement of self-expandable nitinol stents in patients with esophageal and upper GI obstruction. We retrospectively reviewed the medical records and results of computed tomography and endoscopy of 1485 consecutive patients with esophageal and upper GI obstructions who underwent fluoroscopically guided stent placement. Bleeding occurred in 25 of 1485 (1.7%) patients 0 to 348 days after stent placement. Early stent-related bleeding occurred in 10 patients (40%) and angiographic embolization was used for 5/10. Late bleeding occurred in 15 patients (60%) and endoscopic hemostasis was used for 7/15. Twenty-two of 25 (88%) patients with bleeding had received prior radiotherapy and/or chemotherapy. Bleeding is a rare complication after placement of expandable nitinol stents in patients with esophageal and upper GI obstruction, but patients with early bleeding may require embolization for control. Care must be exercised on placing stents in patients who have received prior radiotherapy or chemotherapy. © The Foundation Acta Radiologica 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  9. View-Dependent Simplification of Arbitrary Polygonal Environments

    DTIC Science & Technology

    2006-01-01

    of backfacing nodes are not rendered [ Kumar 96]. 4.3 Triangle-Budget Simplification The screenspace error threshold and silhouette test allow the user...Greg Turk, and Dinesh Manocha for their invaluable guidance and support throughout this project. Funding for this work was provided by DARPA...Proceedings Visualization 95 , IEEE Computer Society Press (Atlanta, GA), 1995, pp. 296-303. [ Kumar 96] Kumar , Subodh, D. Manocha, W. Garrett, M. Lin

  10. The Present Status of the Field of Digital Computer Based Industrial Control Systems and the Work of the International Purdue Workshop in Helping to Promote this Field

    DTIC Science & Technology

    1978-09-01

    Strategy for a Class of Static Systems", IEEE Trans, on Auto. Cont., AC-17, 7-15 (1972). 14. Findeisen , W., and Lefkowitz, I., "Design and Applications...of Multilayer Control", Proc. Fourth IFAC Congress, Warsaw, 1969. 15. Findeisen , W., Multilevel Control Systems, Panstwowe Wydawnictwo Naukowe

  11. High-Fidelity Design of Multimodal Restorative Interventions in Gulf War Illness

    DTIC Science & Technology

    2017-10-01

    Bockmayr A, Klarner H, Siebert H. Time series dependent analysis of unparametrized Thomas networks. IEEE/ACM Transactions on Computational Biology and...Award Number: W81XWH-15-1-0582 TITLE:High-Fidelity Design of Multimodal Restorative Interventions in Gulf War Illness PRINCIPAL INVESTIGATOR...not be construed as an official Department of the Army position, policy or decision unless so designated by other documentation. REPORT

  12. Observation Uncertainty in Gaussian Sensor Networks

    DTIC Science & Technology

    2006-01-23

    Ziv , J., and Lempel , A. A universal algorithm for sequential data compression . IEEE Transactions on Information Theory 23, 3 (1977), 337–343. 73 ...using the Lempel - Ziv algorithm [42], context-tree weighting [41], or the Burrows-Wheeler Trans- form [4], [15], for example. These source codes will...and Computation (Monticello, IL, September 2004). [4] Burrows, M., and Wheeler, D. A block sorting lossless data compression algorithm . Tech.

  13. Investigation of a Nanowire Electronic Nose by Computer Simulation

    DTIC Science & Technology

    2009-04-14

    R. D. Mileham, and D. W. Galipeau. Gas sensing based on inelastic electron tunneling spectroscopy. IEEE Sensors Journal, 8(6):983988, 2008. [6] J...explosives in the hold of passenger aircraft . More generally they can be used to detect the presence of molecules that could be a threat to human health...design suitable for subsequent fabrication and then characterization. 15. SUBJECT TERMS EOARD, Sensor Technology, electronic

  14. A Spatiotemporal Clustering Approach to Maritime Domain Awareness

    DTIC Science & Technology

    2013-09-01

    1997. [25] M. E. Celebi, “Effective initialization of k-means for color quantization,” 16th IEEE International Conference on Image Processing (ICIP...release; distribution is unlimited 12b. DISTRIBUTION CODE 13. ABSTRACT (maximum 200 words) Spatiotemporal clustering is the process of grouping...Department of Electrical and Computer Engineering iv THIS PAGE INTENTIONALLY LEFT BLANK v ABSTRACT Spatiotemporal clustering is the process of

  15. Three-Dimensional Visualization of Ozone Process Data.

    DTIC Science & Technology

    1997-06-18

    Scattered Multivariate Data. IEEE Computer Graphics & Applications. 11 (May), 47-55. Odman, M.T. and Ingram, C.L. (1996) Multiscale Air Quality Simulation...the Multiscale Air Quality Simulation Platform (MAQSIP) modeling system. MAQSIP is a modular comprehensive air quality modeling system which MCNC...photolyzed back again to nitric oxide. Finally, oxides of 6 nitrogen are terminated through loss or combination into nitric acid, organic nitrates

  16. Evaluating the Limits of Network Topology Inference Via Virtualized Network Emulation

    DTIC Science & Technology

    2015-06-01

    76 xi Figure 5.33 Hop-plot of five best reduction methods. KDD most closely matches the Internet plot...respectively, located around the world. These monitors provide locations from which to perform network measurement experiments, primarily using the ping ...International Symposium on Modeling, Analysis and Simulation of Computer Telecommunication Systems. IEEE, 2001, pp. 346–353. 90 [21] C. Jin , Q. Chen, and S

  17. Assisting Design Given Multiple Performance Criteria

    DTIC Science & Technology

    1988-08-01

    with uninstantiated operators is created then each operator’s implementation is selected. g - Keywords: computer-aided design, artificial...IEEE Trans- actions on Software Engineering, SE-7(1), 1981. [BG86] Forrest D. Brewer and Daniel D. Gajski . An expert-system paradigm for de- sign. In...Teukolsky, api William T. Vet- terling. Numerical Recipes. Cambridge University Press, Cambridge, England, 1987. [RFS83] G . G . Rassweiler, M. D

  18. Magnetic hyperthermia controlled drug release in the GI tract: solving the problem of detection.

    PubMed

    Bear, Joseph C; Patrick, P Stephen; Casson, Alfred; Southern, Paul; Lin, Fang-Yu; Powell, Michael J; Pankhurst, Quentin A; Kalber, Tammy; Lythgoe, Mark; Parkin, Ivan P; Mayes, Andrew G

    2016-09-27

    Drug delivery to the gastrointestinal (GI) tract is highly challenging due to the harsh environments any drug- delivery vehicle must experience before it releases it's drug payload. Effective targeted drug delivery systems often rely on external stimuli to effect release, therefore knowing the exact location of the capsule and when to apply an external stimulus is paramount. We present a drug delivery system for the GI tract based on coating standard gelatin drug capsules with a model eicosane- superparamagnetic iron oxide nanoparticle composite coating, which is activated using magnetic hyperthermia as an on-demand release mechanism to heat and melt the coating. We also show that the capsules can be readily detected via rapid X-ray computed tomography (CT) and magnetic resonance imaging (MRI), vital for progressing such a system towards clinical applications. This also offers the opportunity to image the dispersion of the drug payload post release. These imaging techniques also influenced capsule content and design and the delivered dosage form. The ability to easily change design demonstrates the versatility of this system, a vital advantage for modern, patient-specific medicine.

  19. Contrast media for fluoroscopic examinations of the GI and GU tracts: current challenges and recommendations.

    PubMed

    Federle, Michael P; Jaffe, Tracy A; Davis, Peter L; Al-Hawary, Mahmoud M; Levine, Marc S

    2017-01-01

    One of the significant challenges facing radiologists who perform and interpret studies of the gastrointestinal and genitourinary systems have been periodic interruptions in the availability of barium and iodinated contrast media specially formulated for gastrointestinal (GI) and genitourinary (GU) studies. These interruptions are due to the US Food and Drug Administration's recent requirement for more stringent documentation of the safety and efficacy of contrast media and the consolidation among contrast manufacturers. Therefore, radiologists may be required to recommend an alternative means of evaluation, such as computed tomography, magnetic resonance, or endoscopy, or they may need to substitute a different formulation of a contrast agent not specifically developed for GI or GU use, for example the utilization of an agent designed and marketed for vascular use. This article reviews the current status of fluoroscopic contrast media, and provides suggestions and recommendations for the optimal and alternative use of contrast media formulations.

  20. Transpulmonary pressures and lung mechanics with glossopharyngeal insufflation and exsufflation beyond normal lung volumes in competitive breath-hold divers.

    PubMed

    Loring, Stephen H; O'Donnell, Carl R; Butler, James P; Lindholm, Peter; Jacobson, Francine; Ferrigno, Massimo

    2007-03-01

    Throughout life, most mammals breathe between maximal and minimal lung volumes determined by respiratory mechanics and muscle strength. In contrast, competitive breath-hold divers exceed these limits when they employ glossopharyngeal insufflation (GI) before a dive to increase lung gas volume (providing additional oxygen and intrapulmonary gas to prevent dangerous chest compression at depths recently greater than 100 m) and glossopharyngeal exsufflation (GE) during descent to draw air from compressed lungs into the pharynx for middle ear pressure equalization. To explore the mechanical effects of these maneuvers on the respiratory system, we measured lung volumes by helium dilution with spirometry and computed tomography and estimated transpulmonary pressures using an esophageal balloon after GI and GE in four competitive breath-hold divers. Maximal lung volume was increased after GI by 0.13-2.84 liters, resulting in volumes 1.5-7.9 SD above predicted values. The amount of gas in the lungs after GI increased by 0.59-4.16 liters, largely due to elevated intrapulmonary pressures of 52-109 cmH(2)O. The transpulmonary pressures increased after GI to values ranging from 43 to 80 cmH(2)O, 1.6-2.9 times the expected values at total lung capacity. After GE, lung volumes were reduced by 0.09-0.44 liters, and the corresponding transpulmonary pressures decreased to -15 to -31 cmH(2)O, suggesting closure of intrapulmonary airways. We conclude that the lungs of some healthy individuals are able to withstand repeated inflation to transpulmonary pressures far greater than those to which they would normally be exposed.

  1. Transjugular Endovascular Recanalization of Splenic Vein in Patients with Regional Portal Hypertension Complicated by Gastrointestinal Bleeding

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Luo, Xuefeng; Nie, Ling; Wang, Zhu

    PurposeRegional portal hypertension (RPH) is an uncommon clinical syndrome resulting from splenic vein stenosis/occlusion, which may cause gastrointestinal (GI) bleeding from the esophagogastric varices. The present study evaluated the safety and efficacy of transjugular endovascular recanalization of splenic vein in patients with GI bleeding secondary to RPH.MethodsFrom December 2008 to May 2011, 11 patients who were diagnosed with RPH complicated by GI bleeding and had undergone transjugular endovascular recanalization of splenic vein were reviewed retrospectively. Contrast-enhanced computed tomography revealed splenic vein stenosis in six cases and splenic vein occlusion in five. Etiology of RPH was chronic pancreatitis (n = 7), acute pancreatitismore » with pancreatic pseudocyst (n = 2), pancreatic injury (n = 1), and isolated pancreatic tuberculosis (n = 1).ResultsTechnical success was achieved in 8 of 11 patients via the transjugular approach, including six patients with splenic vein stenosis and two patients with splenic vein occlusion. Two patients underwent splenic vein venoplasty only, whereas four patients underwent bare stents deployment and two covered stents. Splenic vein pressure gradient (SPG) was reduced from 21.5 ± 7.3 to 2.9 ± 1.4 mmHg after the procedure (P < 0.01). For the remaining three patients who had technical failures, splenic artery embolization and subsequent splenectomy was performed. During a median follow-up time of 17.5 (range, 3–34) months, no recurrence of GI bleeding was observed.ConclusionsTransjugular endovascular recanalization of splenic vein is a safe and effective therapeutic option in patients with RPH complicated by GI bleeding and is not associated with an increased risk of procedure-related complications.« less

  2. Multimodal Task-Driven Dictionary Learning for Image Classification

    DTIC Science & Technology

    2015-12-18

    1 Multimodal Task-Driven Dictionary Learning for Image Classification Soheil Bahrampour, Student Member, IEEE, Nasser M. Nasrabadi, Fellow, IEEE...Asok Ray, Fellow, IEEE, and W. Kenneth Jenkins, Life Fellow, IEEE Abstract— Dictionary learning algorithms have been suc- cessfully used for both...reconstructive and discriminative tasks, where an input signal is represented with a sparse linear combination of dictionary atoms. While these methods are

  3. Validating the Test Procedures Described in UL 1741 SA and IEEE P1547.1: Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mahmud, Rasel; Hoke, Anderson F; Narang, David J

    This paper investigates the test procedures specified in UL 1741 SA and the upcoming revision to IEEE P1547.1. A 550 kVA photovoltaic inverter was chosen for the tests. This research reveals some of key the components to consider while doing certification tests for UL 1741 SA and IEEE P1547.1. This paper also identifies some issues requiring consideration for future releases of the standard, i.e. IEEE P1547.1. This paper investigates the test procedures specified in UL 1741 SA and the upcoming revision to IEEE P1547.1. A 550 kVA photovoltaic inverter was chosen for the tests. This research reveals some of keymore » the components to consider while doing certification tests for UL 1741 SA and IEEE P1547.1. This paper also identifies some issues requiring consideration for future releases of the standard, i.e. IEEE P1547.1.« less

  4. Multi-task learning with group information for human action recognition

    NASA Astrophysics Data System (ADS)

    Qian, Li; Wu, Song; Pu, Nan; Xu, Shulin; Xiao, Guoqiang

    2018-04-01

    Human action recognition is an important and challenging task in computer vision research, due to the variations in human motion performance, interpersonal differences and recording settings. In this paper, we propose a novel multi-task learning framework with group information (MTL-GI) for accurate and efficient human action recognition. Specifically, we firstly obtain group information through calculating the mutual information according to the latent relationship between Gaussian components and action categories, and clustering similar action categories into the same group by affinity propagation clustering. Additionally, in order to explore the relationships of related tasks, we incorporate group information into multi-task learning. Experimental results evaluated on two popular benchmarks (UCF50 and HMDB51 datasets) demonstrate the superiority of our proposed MTL-GI framework.

  5. Two tradeoffs between economy and reliability in loss of load probability constrained unit commitment

    NASA Astrophysics Data System (ADS)

    Liu, Yuan; Wang, Mingqiang; Ning, Xingyao

    2018-02-01

    Spinning reserve (SR) should be scheduled considering the balance between economy and reliability. To address the computational intractability cursed by the computation of loss of load probability (LOLP), many probabilistic methods use simplified formulations of LOLP to improve the computational efficiency. Two tradeoffs embedded in the SR optimization model are not explicitly analyzed in these methods. In this paper, two tradeoffs including primary tradeoff and secondary tradeoff between economy and reliability in the maximum LOLP constrained unit commitment (UC) model are explored and analyzed in a small system and in IEEE-RTS System. The analysis on the two tradeoffs can help in establishing new efficient simplified LOLP formulations and new SR optimization models.

  6. 46 CFR 111.60-1 - Construction and testing of cable.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... identification of either IEEE 1580, UL 1309, IEC 92-353, or NPFC MIL-C-24640A or NPFC MIL-C-24643A (all five... 110.10-1). (c) Medium-voltage electric cable must meet the requirements of IEEE 1580 and UL 1072... 1309, IEEE 1580, or section 8 of IEEE 45-2002 (incorporated by reference; see 46 CFR 110.10-1). (e...

  7. Baby, Where Did You Get Those Eyes?: IEEE Pulse talks with Mark Sagar about the new face of artificial intelligence.

    PubMed

    Campbell, Sarah

    2015-01-01

    Mark Sagar is changing the way we look at computers by giving them faces?disconcertingly realistic human faces. Sagar first gained widespread recognition for his pioneering work in rendering faces for Hollywood movies, including Avatar and King Kong. With a Ph.D. degree in bioengineering and two Academy Awards under his belt, Sagar now directs a research lab at the University of Auckland, New Zealand, a combinatorial hub where artificial intelligence (AI), neuroscience, computer science, philosophy, and cognitive psychology intersect in creating interactive, intelligent technologies.

  8. Proceedings of the Annual ACM Symposium (11th) on Principles of Distributed Computing Held in Vancouver, British Columbia, Canada on 10-12 Aug 1992

    DTIC Science & Technology

    1992-08-10

    scheduler’s strategy. At the beginning of the is delayed at this state. A routing edge (Si,Tj), execution, the scheduler delays all messages sent for...graph G and Appendix). We remark that the choice of "play" the role ý-’ the scheduler . The scheduler’s constants in the above definition is not...34’ Annmul Symposium ical wakeup . Also, assume that during [t, t + x], for on Foundations of Computer Science. IEEE, t > 2n, a specific route of length at most

  9. Charged Slurry Droplet Research

    DTIC Science & Technology

    1989-02-20

    IEEE/IAS annual meeting, Denver, CO, Sept. 28 - Oct. 3, 1986, p.1434. Accepted for publication IEEE Transactions on Industry Applications. 6. Lord...34Analysis of the Description of Evaporating Charged Droplets, IEEE Transactions on Industry Applications, IA-19, 771, 1983. 9. H.M.A. Elghazaly, G.S.P. Castle...34Analysis of the Instability of Evaporating Charged Liquid Drops", IEEE Transactions on Industry Applications, IA-22, 892, 1986. 10. H.M.A

  10. SAR Product Improvements and Enhancements - SARprises

    DTIC Science & Technology

    2013-09-30

    paper on current fields at Orkney, Scotland, was accepted for publication in IEEE - TGARS and is currently in press (available on IEEE Xplore as Early...Sea surface velocity vector retrieval using dual-beam interferometry: First demonstration, IEEE TGARS, 43, 2494- 2502, 2005. [2] Chapron, B., F...Bight by airborne along-track interferometric SAR, Proc. IGARSS 2002, 1822-1824, IEEE , 2002. [4] Bjerklie, D.M., S.L. Dingman, C.J. Vorosmarty, C.H

  11. Performance Analysis of the IEEE 802.11p Multichannel MAC Protocol in Vehicular Ad Hoc Networks

    PubMed Central

    2017-01-01

    Vehicular Ad Hoc Networks (VANETs) employ multichannel to provide a variety of safety and non-safety applications, based on the IEEE 802.11p and IEEE 1609.4 protocols. The safety applications require timely and reliable transmissions, while the non-safety applications require efficient and high throughput. In the IEEE 1609.4 protocol, operating interval is divided into alternating Control Channel (CCH) interval and Service Channel (SCH) interval with an identical length. During the CCH interval, nodes transmit safety-related messages and control messages, and Enhanced Distributed Channel Access (EDCA) mechanism is employed to allow four Access Categories (ACs) within a station with different priorities according to their criticality for the vehicle’s safety. During the SCH interval, the non-safety massages are transmitted. An analytical model is proposed in this paper to evaluate performance, reliability and efficiency of the IEEE 802.11p and IEEE 1609.4 protocols. The proposed model improves the existing work by taking serval aspects and the character of multichannel switching into design consideration. Extensive performance evaluations based on analysis and simulation help to validate the accuracy of the proposed model and analyze the capabilities and limitations of the IEEE 802.11p and IEEE 1609.4 protocols, and enhancement suggestions are given. PMID:29231882

  12. Performance Analysis of the IEEE 802.11p Multichannel MAC Protocol in Vehicular Ad Hoc Networks.

    PubMed

    Song, Caixia

    2017-12-12

    Vehicular Ad Hoc Networks (VANETs) employ multichannel to provide a variety of safety and non-safety applications, based on the IEEE 802.11p and IEEE 1609.4 protocols. The safety applications require timely and reliable transmissions, while the non-safety applications require efficient and high throughput. In the IEEE 1609.4 protocol, operating interval is divided into alternating Control Channel (CCH) interval and Service Channel (SCH) interval with an identical length. During the CCH interval, nodes transmit safety-related messages and control messages, and Enhanced Distributed Channel Access (EDCA) mechanism is employed to allow four Access Categories (ACs) within a station with different priorities according to their criticality for the vehicle's safety. During the SCH interval, the non-safety massages are transmitted. An analytical model is proposed in this paper to evaluate performance, reliability and efficiency of the IEEE 802.11p and IEEE 1609.4 protocols. The proposed model improves the existing work by taking serval aspects and the character of multichannel switching into design consideration. Extensive performance evaluations based on analysis and simulation help to validate the accuracy of the proposed model and analyze the capabilities and limitations of the IEEE 802.11p and IEEE 1609.4 protocols, and enhancement suggestions are given.

  13. Performance Evaluation and Control of Distributed Computer Communication Networks.

    DTIC Science & Technology

    1985-09-01

    Zukerman, S. Katz, P. Rodriguez, R. Pazos , S. Resheff, Z. Tsai, Z. Zhang, L. Jong, V. Minh. Other participants are the following visiting... Pazos -Rangel "Bandwidth Allocation and Routing in ISDN’s," IEEE Communications Magazine, February 1984. Abstract The goal of communications network design...location and routing for integrated networks - is formulated, and efficient methods for its solution are presented. (2) R.A. Pazos -Rangel "Evaluation

  14. Parallel Ray Tracing Using the Message Passing Interface

    DTIC Science & Technology

    2007-09-01

    software is available for lens design and for general optical systems modeling. It tends to be designed to run on a single processor and can be very...Cameron, Senior Member, IEEE Abstract—Ray-tracing software is available for lens design and for general optical systems modeling. It tends to be designed to...National Aeronautics and Space Administration (NASA), optical ray tracing, parallel computing, parallel pro- cessing, prime numbers, ray tracing

  15. Enhanced Lesion Visualization in Image-Guided Noninvasive Surgery With Ultrasound Phased Arrays

    DTIC Science & Technology

    2001-10-25

    81, 1995. [4] N. Sanghvi et al., “Noninvasive surgery of prostate tissue by high-intensity focused ultrasound ,” IEEE Trans. UFFC, vol. 43, no. 6, pp...ENHANCED LESION VISUALIZATION IN IMAGE-GUIDED NONINVASIVE SURGERY WITH ULTRASOUND PHASED ARRAYS Hui Yao, Pornchai Phukpattaranont and Emad S. Ebbini...Department of Electrical and Computer Engineering University of Minnesota Minneapolis, MN 55455 Abstract- We describe dual-mode ultrasound phased

  16. Dataset Curation through Renders and Ontology Matching

    DTIC Science & Technology

    2015-09-01

    government .001 services .246 furniture store .299 health salon .998 assoc./organization* .029 insurance agency .103 gastronomy .001 gas & automotive .219...Stanley Michael Bileschi. StreetScenes: Towards scene understanding in still images. PhD thesis, Massachusetts Institute of Technology , 2006. 3.5, 4.4...computer animation]. In Compcon’96.’ Technologies for the Information Superhigh- way’Digest of Papers. IEEE, 1996. 2.1 Aharon Bar Hillel and Daphna Weinshall

  17. Software for Avionics.

    DTIC Science & Technology

    1983-01-01

    fonctions gfinbrales et lea uti- litaires fournis en particulier grice 41 UNIX, sont intfigrfs aelon divers points de vue: - par leur accas 41 travers le...Are They Really A Problem? Proceedings, 2nd International Conference On Software Engineering, pp 91-68. Long acCA : IEEE Computer Society. Britton...CD The Hague. Nc KLEINSCIIMIDT, M. Dr Fa. LITEF. Poatfach 774. 7800 Freiburg i. Br., Ge KLEMM, R. Dr FGAN- FFM , D 5 307 Watchberg-Werthhoven. Ge KLENK

  18. YIP Formal Synthesis of Software-Based Control Protocols for Fractionated,Composable Autonomous Systems

    DTIC Science & Technology

    2016-07-08

    Systems Using Automata Theory and Barrier Certifi- cates We developed a sound but incomplete method for the computational verification of specifications...method merges ideas from automata -based model checking with those from control theory including so-called barrier certificates and optimization-based... Automata theory meets barrier certificates: Temporal logic verification of nonlinear systems,” IEEE Transactions on Automatic Control, 2015. [J2] R

  19. Intelligence in Scientific Computing.

    DTIC Science & Technology

    1993-12-31

    simulation) a high-performance controller for a magnetic levitation system - the German Transrapid system. The new control system can stabilize maglev ...techniques. A paper by Feng Zhao and Richard Thornton about the maglev controller designed by his program was presented at the 31st IEEE conference on...Massachusetts Insti- tute of Technology, 1991. Also availible as MIT AITR 1385. Zhao, F. and Thornton, R. "Automatic Design of a Maglev Controller in

  20. A Common Interface Real-Time Multiprocessor Operating System for Embedded Systems

    DTIC Science & Technology

    1991-03-04

    Pressman , a design methodology should show hierarchical organization, lead to modules exhibiting independent functional characteristics, and be derived...Boehm, Barry W. "Software Engineering," Tutorial: Software Design Strategies, 2nd Edition. 35-50. Los Angeles CA: IEEE Computer Society Press, 1981... Pressman , Roger S. Software Engineering: A Practitioner’s Approach, Second Edi- tion. McGraw-Hill Book Company, New York, 1988. 59. Quinn, Michael J

  1. Computer Modeling of Complete IC Fabrication Process.

    DTIC Science & Technology

    1984-01-01

    Venson Shaw 10. C. S. Chang 11. Elizabeth Batson 12. Richard Pinto 13. Jacques Beauduoin SPEAKERS: 1. Tayo Akinwande 2. Dimitri Antoniadis 3. Walter...Numerical Model of Polysilicon Emitter Contacts in Bipolar Transistors,’ To be published IEEE Trans. Electron Devices. [34] M. R. Pinto , R. W. Dutton...Received PhD, Spring 1082) Balaji Swaminathan (Received PhD, Spring 1983) Len Mei Research Associate Michael Kump Research Assistant Mark Pinto Research

  2. Parallel Algorithms for Computer Vision.

    DTIC Science & Technology

    1989-01-01

    34 IEEE Tran. Pattern Ankyaij and Ma- Artifcial Intelligence , Tokyo, 1979. chine Intelligence , 6, 1984. Kirkpatrick, S., C.D. Gelatt, Jr. and M.P. Vecchi...MASSACHUSETTS INST OF TECH CAMBRIDGE ARTIFICIAL INTELLIGENCE LAB T P06010 JAN 89 ETL-0529 UNCLASSIFIED DACA76-85-C-0010 F.’G 12/1I N mommiimmmiiso...PoggioI Massachusetts Institute of Technology i Artificial Intelligence Laboratory 545 Technology Square Cambridge, Massachusetts 02139 DTIC January

  3. The Use of Empirical Studies in the Development of High End Computing Applications

    DTIC Science & Technology

    2009-12-01

    34, Proceeding of 5th ACM-IEEE International Symposium on Empirical Software Engineering (ISESE󈧊), Rio de Janeiro , Brazil, September, 2006. 8. Jeffrey C...Symposium on Empirical Software Engineering, (ISESE), Rio de Janeiro , September, 2006. [26] Zelkowitz M. , V. Basili, S. Asgari, L. Hochstein, J...data is consistently collected across studies. 4. Sanitization of sensitive data. The framework provides external researcher with access to the

  4. Principles of Adaptive Array Processing

    DTIC Science & Technology

    2006-09-01

    ACE with and without tapering (homogeneous case). These analytical results are less suited to predict the detection performance of a real system ...Nickel: Adaptive Beamforming for Phased Array Radars. Proc. Int. Radar Symposium IRS’98 (Munich, Sept. 1998), DGON and VDE /ITG, pp. 897-906.(Reprint also...strategies for airborne radar. Asilomar Conf. on Signals, Systems and Computers, Pacific Grove, CA, 1998, IEEE Cat.Nr. 0-7803-5148-7/98, pp. 1327-1331. [17

  5. Message From the Editor for Contributions to the 2012 Real Time Conference Issue of TNS

    NASA Astrophysics Data System (ADS)

    Schmeling, Sascha Marc

    2013-10-01

    The papers in this special issue were originally presented at the 18th IEEE-NPSS Real Time Conference (RT2012) on Computing Applications in Nuclear and Plasma Sciences, held in Berkeley, California, USA, in June 2012. These contributions come from a broad range of fields of application, including Astrophysics, Medical Imaging, Nuclear and Plasma Physics, Particle Accelerators, and Particle Physics Experiments.

  6. Overhead-Performance Tradeoffs in Distributed Wireless Networks

    DTIC Science & Technology

    2015-06-26

    grew this fraction. See the tutorial for details and acronym definitions. Key Publication & Abstract • Gwanmo Ku and John MacLaren Walsh, Resource...tradeoffs. Key Publication & Abstract • Gwanmo Ku , Jie Ren, and John MacLaren Walsh, Computing the Rate Distortion Region for the CEO Problem with...IID. • Jie Ren, Bradford Boyle, Gwanmo Ku , Steven Weber, John MacLaren Walsh, Overhead Performance Tradeoffs A Resource Allocation Perspective, IEEE

  7. An Overview of MSHN: The Management System for Heterogeneous Networks

    DTIC Science & Technology

    1999-04-01

    An Overview of MSHN: The Management System for Heterogeneous Networks Debra A. Hensgen†, Taylor Kidd†, David St. John§, Matthew C . Schnaidt†, Howard...ABSTRACT UU 18. NUMBER OF PAGES 15 19a. NAME OF RESPONSIBLE PERSON a. REPORT unclassified b. ABSTRACT unclassified c . THIS PAGE...Alhusaini, V. K. Prasanna, and C . S. Raghavendra, “A unified resource scheduling framework for heterogeneous computing environments,” Proc. 8th IEEE

  8. Computational Methods for Design, Control and Optimization

    DTIC Science & Technology

    2007-10-01

    Krueger Eugene M. Cliff Hoan Nguyen Traian Iliescu John Singler James Vance Eric Vugrin Adam Childers Dan Sutton References [11 J. T. Borggaard, S...Control, 45th IEEE Conference on Decision and Control, accepted. [11] L. C. Berselli, T. Iliescu and W. J. Layton , Mathematics of Large Eddy...Daniel Inman, Eric Ruggiero and John Singler, Finite Element For- mulation for Static Control of a Thin Euler-Bernoulli Beam Using Piezoelectric

  9. The Emergence of Compositional Communication in a Synthetic Ethology Framework

    DTIC Science & Technology

    2005-08-12

    34Integrating Language and Cognition: A Cognitive Robotics Approach", invited contribution to IEEE Computational Intelligence Magazine . The first two...papers address the main topic of investigation of the research proposal. In particular, we have introduced a simple structured meaning-signal mapping...Cavalli-Sforza (1982) to investigate analytically the evolution of structured com- munication codes. Let x 6 [0,1] be the proportion of individuals in a

  10. Incidence of Gastrointestinal Bleeding After Percutaneous Coronary Intervention: A Single Center Experience.

    PubMed

    Aziz, Fahad

    2014-02-01

    Gastrointestinal (GI) bleeding is a hemorrhagic complication after percutaneous coronary intervention in patients with acute myocardial infarction. The purpose of the study is to determine predictors of GI bleeding and impact of GI bleeding on the patients undergoing percutaneous coronary intervention. GI bleeding occurred in 6 (7.1%) of 84 patients with STEMI/NSETMI (ST-segment elevated myocardial infarction/Non ST-segment elevated myocardial infarction) undergoing primary percutaneous coronary intervention. Univariate analysis demonstrates that patients with GI bleeding had a significantly higher previous GI bleeding (16.66% vs. 8.6%, P < 0.001). Higher Killip classification at presentation was associated with higher incidence of GI bleeding (61% vs. 18%, P < 0.01). The use of proton pump inhibitors did not reduce the risk of GI bleeding. The GI bleeding in these patients was associated with higher mortality and morbidity in the post percutaneous coronary intervention period. Although, GI bleeding in patients with MI significantly increases mortality and morbidity, previous GI bleeding and higher Killip class are associated with higher incidence of GI bleeding. High-risk patients for GI bleeding can be identified at presentation.

  11. 75 FR 30915 - Computer Matching Program Between the Department of Veterans Affairs (VA) and the Department of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-02

    ..., and reservists, and eligible dependents who have applied for or who are receiving education benefit... Leader, Education Service, Veterans Benefits Administration, Department of Veterans Affairs, 810 Vermont... receiving, or have received education benefit payments under the Post-9/11 GI Bill. These benefit records...

  12. The effect of different methods to compute N on estimates of mixing in stratified flows

    NASA Astrophysics Data System (ADS)

    Fringer, Oliver; Arthur, Robert; Venayagamoorthy, Subhas; Koseff, Jeffrey

    2017-11-01

    The background stratification is typically well defined in idealized numerical models of stratified flows, although it is more difficult to define in observations. This may have important ramifications for estimates of mixing which rely on knowledge of the background stratification against which turbulence must work to mix the density field. Using direct numerical simulation data of breaking internal waves on slopes, we demonstrate a discrepancy in ocean mixing estimates depending on the method in which the background stratification is computed. Two common methods are employed to calculate the buoyancy frequency N, namely a three-dimensionally resorted density field (often used in numerical models) and a locally-resorted vertical density profile (often used in the field). We show that how N is calculated has a significant effect on the flux Richardson number Rf, which is often used to parameterize turbulent mixing, and the turbulence activity number Gi, which leads to errors when estimating the mixing efficiency using Gi-based parameterizations. Supported by ONR Grant N00014-08-1-0904 and LLNL Contract DE-AC52-07NA27344.

  13. How we compute N matters to estimates of mixing in stratified flows

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Arthur, Robert S.; Venayagamoorthy, Subhas K.; Koseff, Jeffrey R.

    We know that most commonly used models for turbulent mixing in the ocean rely on a background stratification against which turbulence must work to stir the fluid. While this background stratification is typically well defined in idealized numerical models, it is more difficult to capture in observations. Here, a potential discrepancy in ocean mixing estimates due to the chosen calculation of the background stratification is explored using direct numerical simulation data of breaking internal waves on slopes. There are two different methods for computing the buoyancy frequencymore » $N$$, one based on a three-dimensionally sorted density field (often used in numerical models) and the other based on locally sorted vertical density profiles (often used in the field), are used to quantify the effect of$$N$$on turbulence quantities. It is shown that how$$N$$is calculated changes not only the flux Richardson number$$R_{f}$$, which is often used to parameterize turbulent mixing, but also the turbulence activity number or the Gibson number$$Gi$$, leading to potential errors in estimates of the mixing efficiency using$$Gi$-based parameterizations.« less

  14. How we compute N matters to estimates of mixing in stratified flows

    DOE PAGES

    Arthur, Robert S.; Venayagamoorthy, Subhas K.; Koseff, Jeffrey R.; ...

    2017-10-13

    We know that most commonly used models for turbulent mixing in the ocean rely on a background stratification against which turbulence must work to stir the fluid. While this background stratification is typically well defined in idealized numerical models, it is more difficult to capture in observations. Here, a potential discrepancy in ocean mixing estimates due to the chosen calculation of the background stratification is explored using direct numerical simulation data of breaking internal waves on slopes. There are two different methods for computing the buoyancy frequencymore » $N$$, one based on a three-dimensionally sorted density field (often used in numerical models) and the other based on locally sorted vertical density profiles (often used in the field), are used to quantify the effect of$$N$$on turbulence quantities. It is shown that how$$N$$is calculated changes not only the flux Richardson number$$R_{f}$$, which is often used to parameterize turbulent mixing, but also the turbulence activity number or the Gibson number$$Gi$$, leading to potential errors in estimates of the mixing efficiency using$$Gi$-based parameterizations.« less

  15. Testing the Effectiveness of the North Shore - LIJ Health System’s Bioterrorism Response Program to Identified Surveillance Data

    DTIC Science & Technology

    2007-03-01

    Enteritis GI 008.5 ENTERITIS, BACTERIAL NOS Enteritis GI 008.6 ENTERITIS D/T SPECIFIED V Enteritis GI 008.61 ENTERITIS D/T ROTAVIRUS Enteritis GI...008.61 ENTERITIS D/T ROTAVIRUS Enteritis GI 008.62 ENTERITIS D/T ADENOVIRUS Enteritis GI 008.63 ENTERITIS D/T NORWALK VIR Enteritis GI 008.64

  16. Differential immune responses and microbiota profiles in children with autism spectrum disorders and co-morbid gastrointestinal symptoms.

    PubMed

    Rose, Destanie R; Yang, Houa; Serena, Gloria; Sturgeon, Craig; Ma, Bing; Careaga, Milo; Hughes, Heather K; Angkustsiri, Kathy; Rose, Melissa; Hertz-Picciotto, Irva; Van de Water, Judy; Hansen, Robin L; Ravel, Jacques; Fasano, Alessio; Ashwood, Paul

    2018-05-01

    Many studies have reported the increased presence of gastrointestinal (GI) symptoms in children with autism spectrum disorders (ASD). Altered microbiome profiles, pro-inflammatory responses and impaired intestinal permeability have been observed in children with ASD and co-morbid GI symptoms, yet few studies have compared these findings to ASD children without GI issues or similarly aged typical developing children. The aim of this study was to determine whether there are biological signatures in terms of immune dysfunction and microbiota composition in children with ASD with GI symptoms. Children were enrolled in one of four groups: ASD and GI symptoms of irregular bowel habits (ASD GI ), children with ASD but without current or previous GI symptoms (ASD NoGI ), typically developing children with GI symptoms (TD GI ) and typically developing children without current or previous GI symptoms (TD NoGI ). Peripheral blood mononuclear cells (PBMC) were isolated from the blood, stimulated and assessed for cytokine production, while stool samples were analyzed for microbial composition. Following Toll-Like receptor (TLR)-4 stimulation, the ASD GI group produced increased levels of mucosa-relevant cytokines including IL-5, IL-15 and IL-17 compared to ASD NoGI . The production of the regulatory cytokine TGFβ1 was decreased in the ASD GI group compared with both the ASD NoGI and TD NoGI groups. Analysis of the microbiome at the family level revealed differences in microbiome composition between ASD and TD children with GI symptoms; furthermore, a predictive metagenome functional content analysis revealed that pathways were differentially represented between ASD and TD subjects, independently of the presence of GI symptoms. The ASD GI also showed an over-representation of the gene encoding zonulin, a molecule regulating gut permeability, compared to the other groups. Overall our findings suggest that children with ASD who experience GI symptoms have an imbalance in their immune response, possibly influenced by or influencing metagenomic changes, and may have a propensity to impaired gut barrier function which may contribute to their symptoms and clinical outcome. Copyright © 2018 Elsevier Inc. All rights reserved.

  17. A grammar inference approach for predicting kinase specific phosphorylation sites.

    PubMed

    Datta, Sutapa; Mukhopadhyay, Subhasis

    2015-01-01

    Kinase mediated phosphorylation site detection is the key mechanism of post translational mechanism that plays an important role in regulating various cellular processes and phenotypes. Many diseases, like cancer are related with the signaling defects which are associated with protein phosphorylation. Characterizing the protein kinases and their substrates enhances our ability to understand the mechanism of protein phosphorylation and extends our knowledge of signaling network; thereby helping us to treat such diseases. Experimental methods for predicting phosphorylation sites are labour intensive and expensive. Also, manifold increase of protein sequences in the databanks over the years necessitates the improvement of high speed and accurate computational methods for predicting phosphorylation sites in protein sequences. Till date, a number of computational methods have been proposed by various researchers in predicting phosphorylation sites, but there remains much scope of improvement. In this communication, we present a simple and novel method based on Grammatical Inference (GI) approach to automate the prediction of kinase specific phosphorylation sites. In this regard, we have used a popular GI algorithm Alergia to infer Deterministic Stochastic Finite State Automata (DSFA) which equally represents the regular grammar corresponding to the phosphorylation sites. Extensive experiments on several datasets generated by us reveal that, our inferred grammar successfully predicts phosphorylation sites in a kinase specific manner. It performs significantly better when compared with the other existing phosphorylation site prediction methods. We have also compared our inferred DSFA with two other GI inference algorithms. The DSFA generated by our method performs superior which indicates that our method is robust and has a potential for predicting the phosphorylation sites in a kinase specific manner.

  18. Perceived Barriers to Application of Glycaemic Index: Valid Concerns or Lost in Translation?

    PubMed Central

    Grant, Shannan M.; Wolever, Thomas M. S.

    2011-01-01

    The term glycaemic-index (GI) originally appeared in the literature in the early 1980s. GI categorizes carbohydrate according to glycaemic effect postprandially. Since its inception, GI has obtained and maintained interest of academics and clinicians globally. Upon review of GI literature, it becomes clear that the clinical utility of GI is a source of controversy. Can and should GI be applied clinically? There are academics and clinicians on both sides of the argument. Certainly, this controversy has been a stimulus for the evolution of GI methodology and application research, but may also negatively impact clinicians’ perception of GI if misunderstood. This article reviews two assessments of GI that are often listed as barriers to application; the GI concept is (1) too complex and (2) too difficult for clients to apply. The literature reviewed does not support the majority of purported barriers, but does indicate that there is a call from clinicians for more and improved GI education tools and clinician GI education. The literature indicates that the Registered Dietitian (RD) can play a key role in GI knowledge translation; from research to application. Research is warranted to assess GI education tool and knowledge needs of clinicians and the clients they serve. PMID:22254100

  19. Flexible Description Language for HPC based Processing of Remote Sense Data

    NASA Astrophysics Data System (ADS)

    Nandra, Constantin; Gorgan, Dorian; Bacu, Victor

    2016-04-01

    When talking about Big Data, the most challenging aspect lays in processing them in order to gain new insight, find new patterns and gain knowledge from them. This problem is likely most apparent in the case of Earth Observation (EO) data. With ever higher numbers of data sources and increasing data acquisition rates, dealing with EO data is indeed a challenge [1]. Geoscientists should address this challenge by using flexible and efficient tools and platforms. To answer this trend, the BigEarth project [2] aims to combine the advantages of high performance computing solutions with flexible processing description methodologies in order to reduce both task execution times and task definition time and effort. As a component of the BigEarth platform, WorDeL (Workflow Description Language) [3] is intended to offer a flexible, compact and modular approach to the task definition process. WorDeL, unlike other description alternatives such as Python or shell scripts, is oriented towards the description topologies, using them as abstractions for the processing programs. This feature is intended to make it an attractive alternative for users lacking in programming experience. By promoting modular designs, WorDeL not only makes the processing descriptions more user-readable and intuitive, but also helps organizing the processing tasks into independent sub-tasks, which can be executed in parallel on multi-processor platforms in order to improve execution times. As a BigEarth platform [4] component, WorDeL represents the means by which the user interacts with the system, describing processing algorithms in terms of existing operators and workflows [5], which are ultimately translated into sets of executable commands. The WorDeL language has been designed to help in the definition of compute-intensive, batch tasks which can be distributed and executed on high-performance, cloud or grid-based architectures in order to improve the processing time. Main references for further information: [1] Gorgan, D., "Flexible and Adaptive Processing of Earth Observation Data over High Performance Computation Architectures", International Conference and Exhibition Satellite 2015, August 17-19, Houston, Texas, USA. [2] Bigearth project - flexible processing of big earth data over high performance computing architectures. http://cgis.utcluj.ro/bigearth, (2014) [3] Nandra, C., Gorgan, D., "Workflow Description Language for Defining Big Earth Data Processing Tasks", Proceedings of the Intelligent Computer Communication and Processing (ICCP), IEEE-Press, pp. 461-468, (2015). [4] Bacu, V., Stefan, T., Gorgan, D., "Adaptive Processing of Earth Observation Data on Cloud Infrastructures Based on Workflow Description", Proceedings of the Intelligent Computer Communication and Processing (ICCP), IEEE-Press, pp.444-454, (2015). [5] Mihon, D., Bacu, V., Colceriu, V., Gorgan, D., "Modeling of Earth Observation Use Cases through the KEOPS System", Proceedings of the Intelligent Computer Communication and Processing (ICCP), IEEE-Press, pp. 455-460, (2015).

  20. The glycaemic index: importance of dietary fibre and other food properties.

    PubMed

    Björck, Inger; Elmståhl, Helena Liljeberg

    2003-02-01

    An increasing body of evidence suggests that a low-glycaemic-index (GI) diet has a therapeutic as well as a preventive potential in relation to the insulin resistance syndrome. The implementation of a low-GI diet, however, will require an extended list of low-GI foods to be available on the market. The tailoring of low-GI bread products offers a particular challenge due to their generally high GI and abundance in the diet. Low-GI bread products can be tailored by, for example,enclosure of cereal kernels, sour dough fermentation and/or addition of organic acids, or use of cereal genotypes with elevated contents of amylose or f-glucans. Low-GI cereal foods appear to vary in effect on 'second-meal' glucose tolerance in healthy subjects. In addition to the slow-release properties of such foods, the content of dietary fibre appears to play a role. The low glycaemia to starch in a pasta breakfast (GI 54) promoted a higher glucose tolerance and lowered triacylglycerol levels at a standardized lunch ingested 4 h later, compared with a white-wheat-bread breakfast (GI 100). The metabolic benefits of the low GI properties per se have been demonstrated also in the longer term. Thus, a reduction in dietary GI improved glucose and lipid metabolism and normalized fibrinolytic activity in type 2 diabetics, while maintaining a similar amount and composition of dietary fibre. However, the higher dietary fibre content frequently associated with low-GI foods may add to the metabolic merits of a low-GI diet. Consequently, a low-GI barley meal rich in dietary fibre (GI 53) improved glucose tolerance from evening meal to breakfast, whereas an evening meal with pasta had no effect (GI 54). The exchange of common high-GI bread for low-GI high-fibre bread, as the only dietary modification, improved insulin economy in women at risk of type 2 diabetes. These results are in accordance with epidemiological evidence of a reduced risk of type 2 diabetes with a low-GI diet rich in cereal fibre. It is concluded that low-GI cereal foods developed should preferably be rich in dietary fibre.

  1. Incidence and mitigation of gastrointestinal events in patients with relapsing-remitting multiple sclerosis receiving delayed-release dimethyl fumarate: a German phase IV study (TOLERATE).

    PubMed

    Gold, Ralf; Schlegel, Eugen; Elias-Hamp, Birte; Albert, Christian; Schmidt, Stephan; Tackenberg, Björn; Xiao, James; Schaak, Tom; Salmen, Hans Christian

    2018-01-01

    Gastrointestinal (GI) events are common adverse events (AEs) associated with delayed-release dimethyl fumarate (DMF), an approved treatment for relapsing-remitting multiple sclerosis (RRMS). The objective of the TOLERATE study was to evaluate GI tolerability and GI mitigation via symptomatic therapies in patients initiating DMF in a real-world clinical setting in Germany. TOLERATE was a multicentre, open-label, single-arm study performed at 25 German sites. Endpoints were frequency, severity, duration (all primary) and mitigation of GI-related events (secondary). Patients were instructed to take DMF according to the prescribing information for up to 12 weeks and to document GI events and intake of GI-symptomatic therapy on numerical rating scales, using eDiaries. A total of 211 patients were included in the safety population (71% female; mean age 40 ± 11 years). Of these, 185 patients (87.7%) reported GI-related events, out of which nearly half received GI-symptomatic therapy (84/185; 45.4%). The most frequently reported GI events were upper abdominal pain, flatulence and nausea. GI-related events peaked during the first 3 weeks of therapy and rapidly decreased thereafter. The severity of GI events over 12 weeks according to the Modified Overall Gastrointestinal Symptom Scale were mild to moderate in the majority of patients reporting GI-related events and taking symptomatic GI medication (53.6%). Only 10% of all patients discontinued study treatment due to AEs in general, while 6.6% discontinued due to GI-related events. The severity of GI-related events decreased over time in patients who received symptomatic treatment with one or more medications (e.g. acid secretion blockers, antidiarrhoeals or antiemetics). Gastrointestinal events associated with delayed-release DMF were mainly mild to moderate in severity. Prevalence of GI events peaked during the first 3 weeks of therapy and rapidly faded thereafter. Although 44.9% of patients experiencing GI events used common GI symptomatic therapies, only 6.6% of patients discontinued DMF because of GI events, suggesting that GI events could be managed well with common symptomatic therapy.

  2. Gastrointestinal cancer risk in patients with a family history of gastrointestinal cancer.

    PubMed

    Chung, Joo Won; Park, Jae Jun; Lim, Yun Jeong; Lee, Jun; Kim, Sun Moon; Han, Joung Ho; Jeon, Seong Ran; Lee, Hong Sub; Kim, Yong Sung; Song, Si Young

    2018-06-25

    This study was performed to evaluate the relationship between family history of gastrointestinal (GI) cancers and incidence of any GI cancer in the Korean population. Between January 2015 and July 2016, 711 GI cancer patients and 849 controls in 16 hospitals in Korea were enrolled. Personal medical histories, life styles, and family history of GI cancers were collected via questionnaire. There was a significant difference in the incidence of family history of GI cancer between GI cancer patients and controls (p=0.002). Patients with family history of GI cancer tended to be diagnosed as GI cancer at younger age than those without family history (p=0.016). The family members of GI cancer patients who were diagnosed before 50 years of age were more frequently diagnosed as GI cancer before the age of 50 years (p=0.017). After adjusting for major confounding factors, age (adjusted odds ratio [AOR] 1.065, 95% confidence interval [CI]; 1.053-1.076), male gender (AOR 2.270, 95% CI; 1.618-3.184), smoking (AOR 1.570, 95% CI; 1.130-2.182), and sibling's history of GI cancer (AOR 1.973, 95% CI; 1.246-3.126) remained independently associated with GI cancers. GI cancer patients tended to have a first relative with a history of concordant GI cancer. Personal factors (old age and male) and lifestyle (smoking) contribute to the development of GI cancer, independently. Individuals with high risk for GI cancers may be advised to undergo screening at an earlier age.

  3. Some issues related to simulation of the tracking and communications computer network

    NASA Technical Reports Server (NTRS)

    Lacovara, Robert C.

    1989-01-01

    The Communications Performance and Integration branch of the Tracking and Communications Division has an ongoing involvement in the simulation of its flight hardware for Space Station Freedom. Specifically, the communication process between central processor(s) and orbital replaceable units (ORU's) is simulated with varying degrees of fidelity. The results of investigations into three aspects of this simulation effort are given. The most general area involves the use of computer assisted software engineering (CASE) tools for this particular simulation. The second area of interest is simulation methods for systems of mixed hardware and software. The final area investigated is the application of simulation methods to one of the proposed computer network protocols for space station, specifically IEEE 802.4.

  4. Some issues related to simulation of the tracking and communications computer network

    NASA Astrophysics Data System (ADS)

    Lacovara, Robert C.

    1989-12-01

    The Communications Performance and Integration branch of the Tracking and Communications Division has an ongoing involvement in the simulation of its flight hardware for Space Station Freedom. Specifically, the communication process between central processor(s) and orbital replaceable units (ORU's) is simulated with varying degrees of fidelity. The results of investigations into three aspects of this simulation effort are given. The most general area involves the use of computer assisted software engineering (CASE) tools for this particular simulation. The second area of interest is simulation methods for systems of mixed hardware and software. The final area investigated is the application of simulation methods to one of the proposed computer network protocols for space station, specifically IEEE 802.4.

  5. Visuospatial skills and computer game experience influence the performance of virtual endoscopy.

    PubMed

    Enochsson, Lars; Isaksson, Bengt; Tour, René; Kjellin, Ann; Hedman, Leif; Wredmark, Torsten; Tsai-Felländer, Li

    2004-11-01

    Advanced medical simulators have been introduced to facilitate surgical and endoscopic training and thereby improve patient safety. Residents trained in the Procedicus Minimally Invasive Surgical Trainer-Virtual Reality (MIST-VR) laparoscopic simulator perform laparoscopic cholecystectomy safer and faster than a control group. Little has been reported regarding whether factors like gender, computer experience, and visuospatial tests can predict the performance with a medical simulator. Our aim was to investigate whether such factors influence the performance of simulated gastroscopy. Seventeen medical students were asked about computer gaming experiences. Before virtual endoscopy, they performed the visuospatial test PicCOr, which discriminates the ability of the tested person to create a three-dimensional image from a two-dimensional presentation. Each student performed one gastroscopy (level 1, case 1) in the GI Mentor II, Simbionix, and several variables related to performance were registered. Percentage of time spent with a clear view in the endoscope correlated well with the performance on the PicSOr test (r = 0.56, P < 0.001). Efficiency of screening also correlated with PicSOr (r = 0.23, P < 0.05). In students with computer gaming experience, the efficiency of screening increased (33.6% +/- 3.1% versus 22.6% +/- 2.8%, P < 0.05) and the duration of the examination decreased by 1.5 minutes (P < 0.05). A similar trend was seen in men compared with women. The visuospatial test PicSOr predicts the results with the endoscopic simulator GI Mentor II. Two-dimensional image experience, as in computer games, also seems to affect the outcome.

  6. Achievable Rate Estimation of IEEE 802.11ad Visual Big-Data Uplink Access in Cloud-Enabled Surveillance Applications.

    PubMed

    Kim, Joongheon; Kim, Jong-Kook

    2016-01-01

    This paper addresses the computation procedures for estimating the impact of interference in 60 GHz IEEE 802.11ad uplink access in order to construct visual big-data database from randomly deployed surveillance camera sensing devices. The acquired large-scale massive visual information from surveillance camera devices will be used for organizing big-data database, i.e., this estimation is essential for constructing centralized cloud-enabled surveillance database. This performance estimation study captures interference impacts on the target cloud access points from multiple interference components generated by the 60 GHz wireless transmissions from nearby surveillance camera devices to their associated cloud access points. With this uplink interference scenario, the interference impacts on the main wireless transmission from a target surveillance camera device to its associated target cloud access point with a number of settings are measured and estimated under the consideration of 60 GHz radiation characteristics and antenna radiation pattern models.

  7. Automatic metro map layout using multicriteria optimization.

    PubMed

    Stott, Jonathan; Rodgers, Peter; Martínez-Ovando, Juan Carlos; Walker, Stephen G

    2011-01-01

    This paper describes an automatic mechanism for drawing metro maps. We apply multicriteria optimization to find effective placement of stations with a good line layout and to label the map unambiguously. A number of metrics are defined, which are used in a weighted sum to find a fitness value for a layout of the map. A hill climbing optimizer is used to reduce the fitness value, and find improved map layouts. To avoid local minima, we apply clustering techniques to the map-the hill climber moves both stations and clusters when finding improved layouts. We show the method applied to a number of metro maps, and describe an empirical study that provides some quantitative evidence that automatically-drawn metro maps can help users to find routes more efficiently than either published maps or undistorted maps. Moreover, we have found that, in these cases, study subjects indicate a preference for automatically-drawn maps over the alternatives. © 2011 IEEE Published by the IEEE Computer Society

  8. An SNMP-based solution to enable remote ISO/IEEE 11073 technical management.

    PubMed

    Lasierra, Nelia; Alesanco, Alvaro; García, José

    2012-07-01

    This paper presents the design and implementation of an architecture based on the integration of simple network management protocol version 3 (SNMPv3) and the standard ISO/IEEE 11073 (X73) to manage technical information in home-based telemonitoring scenarios. This architecture includes the development of an SNMPv3-proxyX73 agent which comprises a management information base (MIB) module adapted to X73. In the proposed scenario, medical devices (MDs) send information to a concentrator device [designated as compute engine (CE)] using the X73 standard. This information together with extra information collected in the CE is stored in the developed MIB. Finally, the information collected is available for remote access via SNMP connection. Moreover, alarms and events can be configured by an external manager in order to provide warnings of irregularities in the MDs' technical performance evaluation. This proposed SNMPv3 agent provides a solution to integrate and unify technical device management in home-based telemonitoring scenarios fully adapted to X73.

  9. Trustworthy data collection from implantable medical devices via high-speed security implementation based on IEEE 1363.

    PubMed

    Hu, Fei; Hao, Qi; Lukowiak, Marcin; Sun, Qingquan; Wilhelm, Kyle; Radziszowski, Stanisław; Wu, Yao

    2010-11-01

    Implantable medical devices (IMDs) have played an important role in many medical fields. Any failure in IMDs operations could cause serious consequences and it is important to protect the IMDs access from unauthenticated access. This study investigates secure IMD data collection within a telehealthcare [mobile health (m-health)] network. We use medical sensors carried by patients to securely access IMD data and perform secure sensor-to-sensor communications between patients to relay the IMD data to a remote doctor's server. To meet the requirements on low computational complexity, we choose N-th degree truncated polynomial ring (NTRU)-based encryption/decryption to secure IMD-sensor and sensor-sensor communications. An extended matryoshkas model is developed to estimate direct/indirect trust relationship among sensors. An NTRU hardware implementation in very large integrated circuit hardware description language is studied based on industry Standard IEEE 1363 to increase the speed of key generation. The performance analysis results demonstrate the security robustness of the proposed IMD data access trust model.

  10. Real Time Conference 2016 Overview

    NASA Astrophysics Data System (ADS)

    Luchetta, Adriano

    2017-06-01

    This is a special issue of the IEEE Transactions on Nuclear Science containing papers from the invited, oral, and poster presentation of the 20th Real Time Conference (RT2016). The conference was held June 6-10, 2016, at Centro Congressi Padova “A. Luciani,” Padova, Italy, and was organized by Consorzio RFX (CNR, ENEA, INFN, Università di Padova, Acciaierie Venete SpA) and the Istituto Nazionale di Fisica Nucleare. The Real Time Conference is multidisciplinary and focuses on the latest developments in real-time techniques in high-energy physics, nuclear physics, astrophysics and astroparticle physics, nuclear fusion, medical physics, space instrumentation, nuclear power instrumentation, general radiation instrumentation, and real-time security and safety. Taking place every second year, it is sponsored by the Computer Application in Nuclear and Plasma Sciences technical committee of the IEEE Nuclear and Plasma Sciences Society. RT2016 attracted more than 240 registrants, with a large proportion of young researchers and engineers. It had an attendance of 67 students from many countries.

  11. A mathematical problem and a Spacecraft Control Laboratory Experiment (SCOLE) used to evaluate control laws for flexible spacecraft. NASA/IEEE design challenge

    NASA Technical Reports Server (NTRS)

    Taylor, Lawrence W., Jr.; Balakrishnan, A. V.

    1988-01-01

    The problen of controlling large, flexible space systems has been evaluated using computer simulation. In several cases, ground experiments have also been used to validate system performance under more realistic conditions. There remains a need, however, to test additional control laws for flexible spacecraft and to directly compare competing design techniques. A program is discussed which has been initiated to make direct comparisons of control laws for, first, a mathematical problem, then and experimental test article being assembled under the cognizance of the Spacecraft Control Branch at the NASA Langley Research Center with the advice and counsel of the IEEE Subcommittee on Large Space Structures. The physical apparatus will consist of a softly supported dynamic model of an antenna attached to the Shuttle by a flexible beam. The control objective will include the task of directing the line-of-sight of the Shuttle antenna configuration toward a fixed target, under conditions of noisy data, control authority and random disturbances.

  12. Moving Up the CMMI Capability and Maturity Levels Using Simulation

    DTIC Science & Technology

    2008-01-01

    Alternative Process Tools, Including NPV and ROI 6 Figure 3: Top-Level View of the Full Life-Cycle Version of the IEEE 12207 PSIM, Including IV&V Layer 19...Figure 4: Screenshot of the Incremental Version Model 19 Figure 5: IEEE 12207 PSIM Showing the Top-Level Life-Cycle Phases 22 Figure 6: IEEE 12207 ...Software Detailed Design for the IEEE 12207 Life- Cycle Process 24 Figure 8: Incremental Life Cycle PSIM Configured for a Specific Project Using SEPG

  13. Sonobuoy-Based, 3-D Acoustic Characterization of Shallow-Water Environments

    DTIC Science & Technology

    2015-09-30

    10.1109/JOE.2014.2362838, ( IEEE Xplore Early Access, 4 Dec 2014)]. For each type of buoy, the eigenvalues at 50, 75, 125, and 175 Hz were used as input...using sonobuoys,” IEEE J. Ocean. Eng., vol. 40, no. 3, pp. 607-620, Jul. 2015 (DOI: 10.1109/JOE.2014.2362838, ( IEEE Xplore Early Access, 4 Dec 2014...et al, “Modal mapping experiment and geoacoustic inversion using sonobuoys,” IEEE J. Ocean. Eng., vol. 40, no. 3, pp. 607- 620, Jul. 2015 (DOI

  14. Pre-clinical and Clinical Evaluation of High Resolution, Mobile Gamma Camera and Positron Imaging Devices

    DTIC Science & Technology

    2010-10-01

    Downloaded on February 20,2010 at 10:55:59 EST from IEEE Xplore . Restrictions apply. STUDENSKI et al.: ACQUISITION AND PROCESSING METHODS FOR A BEDSIDE...February 20,2010 at 10:55:59 EST from IEEE Xplore . Restrictions apply. 208 IEEE TRANSACTIONS ON NUCLEAR SCIENCE, VOL. 57, NO. 1, FEBRUARY 2010 from the...59 EST from IEEE Xplore . Restrictions apply. STUDENSKI et al.: ACQUISITION AND PROCESSING METHODS FOR A BEDSIDE CARDIAC SPECT IMAGING SYSTEM 209

  15. Effect of Interface States on the Performance of Antimonide nMOSFETs

    DTIC Science & Technology

    2013-01-14

    Member, IEEE, Himanshu Madan , Student Member, IEEE, Michael J. Barth, J. Brad Boos, Member, IEEE, Brian R. Bennett, and Suman Datta, Fellow, IEEE...now with Intel Corporation, Hillsboro, OR 97124 USA (e-mail: AshkarAli@psualum.com). H. Madan , M. J. Barth, and S. Datta are with the Pennsylvania...S. Chau, “Sb-based CMOS devices,” U.S. Patent 7 429 747, Sep. 30, 2008. [2] A. Ali, H. Madan , A. Agrawal, I. Ramirez, R. Misra, J. B. Boos, B. R

  16. Advantageous developmental outcomes of advancing paternal age

    PubMed Central

    Janecka, M; Rijsdijk, F; Rai, D; Modabbernia, A; Reichenberg, A

    2017-01-01

    Advanced paternal age (APA) at conception has been associated with negative outcomes in offspring, raising concerns about increasing age at fatherhood. Evidence from evolutionary and psychological research, however, suggests possible link between APA and a phenotypic advantage. We defined such advantage as educational success, which is positively associated with future socioeconomic status. We hypothesised that high IQ, strong focus on the subject of interest and little concern about ‘fitting in’ will be associated with such success. Although these traits are continuously distributed in the population, they cluster together in so-called ‘geeks’. We used these measures to compute a ‘geek index’ (GI), and showed it to be strongly predictive of future academic attainment, beyond the independent contribution of the individual traits. GI was associated with paternal age in male offspring only, and mediated the positive effects of APA on education outcomes, in a similar sexually dimorphic manner. The association between paternal age and GI was partly mediated by genetic factors not correlated with age at fatherhood, suggesting contribution of de novo factors to the ‘geeky’ phenotype. Our study sheds new light on the multifaceted nature of the APA effects and explores the intricate links between APA, autism and talent. PMID:28632201

  17. A Bibliography of Packet Radio Literature.

    DTIC Science & Technology

    1984-03-01

    r r* C.C.4. W . . . . . . . . .. . . . Gafni, E. and D. Bertsekas, "Distributed Algorithms for Generating Loop-Free Routes in Networks with Frequently...December 1980). Leiner, B., K. Klemba, and J. Tornow , "Packet Radio Networking," Computer World, pp. 26-37, 30, (September 27, 1982). Liu, J...34Distributed Routing and Relay Management in Mobile Packet Radio Networks," Proceedings IEEE COMPCON Fall 󈨔, p. 235-243 (1980). MacGregor, W ., J. Westcott, and

  18. Design, Implementation, and Characterization of a Dedicated Breast Computed Mammotomography System for Enhanced Lesion Imaging

    DTIC Science & Technology

    2006-03-01

    Evaluation of fully 3D emission mammotomography with a compact cadmium zinc telluride detector,” IEEE Trans. Med. Imag. (Submitted) 2005. [16] M.P...times over a few months, and the degradation due to compromised adipose tissue boundaries as well as other physical breast features are becoming...breast lesions, especially in radiographically dense breasts,2,11-13 through the removal of contrast-reducing overlying tissue ; (2) uncompressed

  19. Co Modeling and Co Synthesis of Safety Critical Multi threaded Embedded Software for Multi Core Embedded Platforms

    DTIC Science & Technology

    2017-03-20

    computation, Prime Implicates, Boolean Abstraction, real- time embedded software, software synthesis, correct by construction software design , model...types for time -dependent data-flow networks". J.-P. Talpin, P. Jouvelot, S. Shukla. ACM-IEEE Conference on Methods and Models for System Design ...information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing   data sources, gathering and

  20. An Internet-style Approach to Managing Wireless Link Errors

    DTIC Science & Technology

    2002-05-01

    implementation I used. Jamshid Mahdavi and Matt Mathis, then at the Pittsburgh Super- computer Center, and Vern Paxson of the Lawrence Berkeley National...Exposition. IEEE CS Press, 2002. [19] P. Bhagwat, P. Bhattacharya, A. Krishna , and S. Tripathi. Enhancing throughput over wireless LANs using channel...performance over wireless networks at the link layer. ACM Mobile Networks and Applications, 5(1):57– 71, March 2000. [97] Vern Paxson and Mark Allman

  1. DIVA (Data Intensive Architecture)

    DTIC Science & Technology

    2004-06-01

    Itanium-based workstation as a test bench for the larger system concepts. 44 10. Publications [Hall99] M. Hall, P. Kogge, J. Koller, P. Diniz ...White, Dr. Pedro Diniz . Mr. Pablo Moissett • Caltech: Dr. Thomas Sterling, Mr. Daniel Savarese • University of Notre Dame: Dr. Peter Kogge, Dr. Jay...IEEE Computer, April 1995, pp. 23-31. [Hall99] M. Hall, P. Kogge, J. Koller, P. Diniz , J. Chame, J. Draper, J. LaCoss, J. Granacki, J. Brockman

  2. Basic EMC (Electromagnetic Compatibility) Technology Advancement for C3 Systems. Volume 1B. Demodulation Radio Frequency Interference Effects in Operational Amplifier Circuits.

    DTIC Science & Technology

    1985-02-01

    Then it follows that H2 (fl,-f 2) (-flf Thus, the total amplitude of the intermodulation signal at fre- quency fAF is given by6 V = V +I mA2 III(fl 1-f...RFI suppression in the manner described. 229 . * . ... ..... 4 -*.-., ,e ’ - ."..~ REFERENCES 1. G. Kaplan , "Computer Aided Design," IEEE Spectrum, Vol

  3. DMPL: Programming and Verifying Distributed Mixed Synchrony and Mixed Critical Software

    DTIC Science & Technology

    2016-06-16

    ference on Intelligent Robots and Systems, pages 1495–1502, Chicago, IL, September 2014. IEEE Computer Society. [21] MADARA website . http://sourceforge.net...4.6 DMPL program for 5- robot reconnaissance example 19 Figure 5.1 Generated C++ code for example DMPL program. In practice, local vari- ables (lines...examples of collision avoidance in multi- robot systems. CMU/SEI-2016-TR-005 | SOFTWARE ENGINEERING INSTITUTE | Carnegie Mellon University vii

  4. Merging Surface Reconstructions of Terrestrial and Airborne LIDAR Range Data

    DTIC Science & Technology

    2009-05-19

    Mangan and R. Whitaker. Partitioning 3D surface meshes using watershed segmentation . IEEE Trans. on Visualization and Computer Graphics, 5(4), pp...Jain, and A. Zakhor. Data Processing Algorithms for Generating Textured 3D Building Facade Meshes from Laser Scans and Camera Images. International...acquired set of overlapping range images into a single mesh [2,9,10]. However, due to the volume of data involved in large scale urban modeling, data

  5. Rapid Prototyping of High Performance Signal Processing Applications

    DTIC Science & Technology

    2011-01-01

    understand- ing broadband wireless networking . Prentice Hall, 2007. [4] J.W.M. Baars, L.R. D’Addario, and A.R. Thompson. Radio astronomy in the... wireless sensor net- works. In Proceedings of the IEEE Real-Time Systems Symposium, pages 214–223, Tucson, Arizona, December 2007. 147 [74] C. Shen, H. Wu...computing platforms. In this region of high performance DSP, rapid prototyping is critical for faster time-to-market (e.g., in the wireless

  6. Radiation Hard Sensors for Surveillance.

    DTIC Science & Technology

    1988-03-11

    track position measurements were noted. E. Heijne (CERN) reported on the degradation of silicon detectors for doses larger than 2x10 11 muons /cm 2...Workshop on Transmission and Emission Computerized Tomography , July 1978, Seoul, Korea Nahmias C., Kenyon D.B., Garnett E.S.: Optimization of...crystal size in emission computed tomography . IEEE Trans ,.-.e Nucl Sci NS-27: 529-532, 1980. Mullani N.A., Ficke D.C., Ter-Pogossian M.M.: Cesium Fluoride

  7. Cooperation Helps Power Saving

    DTIC Science & Technology

    2009-04-07

    the destination node hears the poll, the link between the two nodes is activated. In the original STEM, two radios working on two separate channels... hears the poll, the link between the two nodes is activated. In the original STEM, two radios working on two separate chan- nels are used: one radio is...Computer and Communications Societies. Proceedings. IEEE, vol. 3, pp. 1548–1557 vol.3, 2001. [2] R . Kravets and P. Krishnan, “Application-driven power

  8. Bio-Inspired Computation: Clock-Free, Grid-Free, Scale-Free and Symbol Free

    DTIC Science & Technology

    2015-06-11

    for Prediction Tasks in Spiking Neural Networks ." Artificial Neural Networks and Machine Learning–ICANN 2014. Springer, 2014. pp 635-642. Gibson, T...Henderson, JA and Wiles, J. "Predicting temporal sequences using an event-based spiking neural network incorporating learnable delays." IEEE...Adelaide (2014 Jan). Gibson, T and Wiles, J "Predicting temporal sequences using an event-based spiking neural network incorporating learnable delays" at

  9. Application of Prognostic Health Management in Digital Electronic Systems

    DTIC Science & Technology

    2007-01-01

    variable external supply applied the necessary core power to the processor while the motherboard continued to source power from the ATX supply. By...isolating the processor power from the motherboard power , control over the aging profile of the processor was achieved. Once nominal operating...Physics-of-failure RISC – Reduced Instruction Set Computer RUL – Remaining Useful Life 1 1-4244-0525-4/07/$20.00 ©2007 IEEE. Paper 1326

  10. Implementing the Victory Access Control Framework in a Military Ground Vehicle

    DTIC Science & Technology

    2015-08-01

    Protocol ( SOAP ) message body, but lacked the ability to encrypt individual XML elements within the SOAP body. Several attempts were made to augment the C...Service and both use SOAP and provide freely available WSDLs with similarly defined operations. TS3 even leverages the same XACML engine that is...Characterizing the Performance of SOAP Toolkits”, Fifth IEEE/ACM International Workshop on Grid Computing, pages 365- 372, November 2004. [8] J.A

  11. IEEE Computer Society/Software Engineering Institute Software Process Achievement (SPA) Award 2009

    DTIC Science & Technology

    2011-03-01

    capabilities to our GDM. We also introduced software as a service ( SaaS ) as part our technology solutions and have further enhanced our ability to...model PROSPER Infosys production support methodology Q&P quality and productivity R&D research and development SaaS software as a service ... Software Development Life Cycle (SDLC) 23 Table 10: Scientific Estimation Coverage by Service Line 27 CMU/SEI-2011-TR-008 | vi CMU/SEI-2011

  12. Information Interface Related Standards, Guidelines, and Recommended Practices.

    DTIC Science & Technology

    1985-07-01

    Application Workshop, IEEE, October 1984 (11) Software Portability and Standards, by Ingemar Dahlstrand, Ellis Horwood Ltd., 1984 (12) World of EDP...March 29, 1985, p. 42-48 * 9. "IBM’s Topview Plays to Poor Reviews of Early Users," Computer World , March 4, 1985, p. 5 10. "Lack of Software Standards...Information Symbols ISOiTR 7239-1984 - Development and Principles for Application of Public Information Symbols ISO/TR 8545 -1984 - Technical Drawings

  13. A New Interface Specification Methodology and its Application to Transducer Synthesis

    DTIC Science & Technology

    1988-05-01

    structural, and physical. Within each domain descriptive methods are distinguished by the level of abstraction they emphasize. The Gajski -Kuhn Y...4.2. The Gajski -Kuhn Y-chart’s three axes correspond to three different domains for describing designs: behavioral, structural, and physical. The...Gajski83] D. Gajski , R. Kuhn, Guest Editors’ Introduction: New VLSI Tools, IEEE Computer, Vol. 16, No. 12, December 1983. [Girczyc85] E. Girczyc, R

  14. Current state of the mass storage system reference model

    NASA Technical Reports Server (NTRS)

    Coyne, Robert

    1993-01-01

    IEEE SSSWG was chartered in May 1990 to abstract the hardware and software components of existing and emerging storage systems and to define the software interfaces between these components. The immediate goal is the decomposition of a storage system into interoperable functional modules which vendors can offer as separate commercial products. The ultimate goal is to develop interoperable standards which define the software interfaces, and in the distributed case, the associated protocols to each of the architectural modules in the model. The topics are presented in viewgraph form and include the following: IEEE SSSWG organization; IEEE SSSWG subcommittees & chairs; IEEE standards activity board; layered view of the reference model; layered access to storage services; IEEE SSSWG emphasis; and features for MSSRM version 5.

  15. Present status of endoscopy, therapeutic endoscopy and the endoscopy training system in Indonesia.

    PubMed

    Makmun, Dadang

    2014-04-01

    Recently, Indonesia was ranked as the fourth most populous country in the world. Based on 2012 data, 85000 general practitioners and 25000 specialists are in service around the country. Gastrointestinal (GI) disease remains the most common finding in daily practise, in both outpatient and inpatient settings, and ranks fifth in causing mortality in Indonesia. Management of patients with GI disease involves all health-care levels with the main portion in primary health care. Some are managed by specialists in secondary health care or are referred to tertiary health care. GI endoscopy is one of the main diagnostic and therapeutic modalities in the management of GI disease. Development of GI endoscopy in Indonesia started before World War II and, today, many GI endoscopy procedures are conducted in Indonesia, both diagnostic and therapeutic. Based on August 2013 data, there are 515 GI endoscopists in Indonesia. Most GI endoscopists are competent in carrying out basic endoscopy procedures, whereas only a few carry out advanced endoscopy procedures, including therapeutic endoscopy. Recently, the GI endoscopy training system in Indonesia consists of basic GI endoscopy training of 3-6 months held at 10 GI endoscopy training centers. GI endoscopy training is also eligible as part of a fellowship program of consultant gastroenterologists held at six accredited fellowship centers in Indonesia. Indonesian Society for Digestive Endoscopy in collaboration with GI endoscopy training centers in Indonesia and overseas has been working to increase quality and number of GI endoscopists, covering both basic and advanced GI endoscopy procedures. © 2014 The Author. Digestive Endoscopy © 2014 Japan Gastroenterological Endoscopy Society.

  16. Building an International Collaboration for GeoInformatics

    NASA Astrophysics Data System (ADS)

    Snyder, W. S.; Lehnert, K.; Klump, J.

    2005-12-01

    Geoinformatics (cyberinfrastructure for the geosciences) is being developed as a linked system of sites that provide to the Earth science community a library of research data research-grade tools to manipulate, mine, analyze and model interdisciplinary data, and mechanisms to provide the necessary computational resources for these activities. Our science is global in scope and hence, geoinformatics (GI) must be an international effort. How do we build this international GI? What are the main challenges presented by the political, cultural, organizational, and technical diversity of the global science community that we need to address to achieve a truly global cyberinfrastructure for the Geosciences? GI needs to be developed in an internet-like fashion establishing connections among independent globally distributed sites (`nodes') that will share, link, and integrate their data holdings and services. Independence of the GI pieces with respect to goals, scope, and approaches is critical to sustain commitment from people to build a GI node for which they feel ownership and get credit. This should not be fought by funding agencies - and certainly not by state and federal agencies. Communication, coordination, and collaboration are the core efforts to build the connections, but incentives and resources are required to advance and support them. Part of the coordination effort is development and maintenance of standards. Who should set these standards and govern their modification? Do we need an official international body to do so, and should this be a "governing body" or an "advisory body"? What role should international commissions and bodies such as CODATA/ICSU or IUGS-CGI, international societies and unions, the national geological surveys and other federal agencies play? Guidance from the science community is key to construct a system that geo-researchers will want to use, and that meets their needs. Only when the community endorses GI as a fundamental platform to support science research will we be able to address the challenging question how to insure sustained funding of GI which will undoubtly be a costly effort, convincing governments and funding agencies to invest in a global effort. Perhaps the most challenging problems are cultural ones such as the "my data" issue, the reluctance to share data even if they were generated with public funding. This is slowly being resolved by some funding agencies through moratorium periods for use of data before they are available to everyone, but will require a sustained "education" effort of the geoscience research community. Geoinformatics is the platform for a new paradigm in how we conduct our research. The challenges to building an international GI are quite serious, some might say daunting, but the conveners of this session feel that the effort is not only worth it, but required for the sake of our science research.

  17. Managing large-scale workflow execution from resource provisioning to provenance tracking: The CyberShake example

    USGS Publications Warehouse

    Deelman, E.; Callaghan, S.; Field, E.; Francoeur, H.; Graves, R.; Gupta, N.; Gupta, V.; Jordan, T.H.; Kesselman, C.; Maechling, P.; Mehringer, J.; Mehta, G.; Okaya, D.; Vahi, K.; Zhao, L.

    2006-01-01

    This paper discusses the process of building an environment where large-scale, complex, scientific analysis can be scheduled onto a heterogeneous collection of computational and storage resources. The example application is the Southern California Earthquake Center (SCEC) CyberShake project, an analysis designed to compute probabilistic seismic hazard curves for sites in the Los Angeles area. We explain which software tools were used to build to the system, describe their functionality and interactions. We show the results of running the CyberShake analysis that included over 250,000 jobs using resources available through SCEC and the TeraGrid. ?? 2006 IEEE.

  18. Genotype I of Japanese Encephalitis Virus Virus-like Particles Elicit Sterilizing Immunity against Genotype I and III Viral Challenge in Swine.

    PubMed

    Fan, Yi-Chin; Chen, Jo-Mei; Lin, Jen-Wei; Chen, Yi-Ying; Wu, Guan-Hong; Su, Kuan-Hsuan; Chiou, Ming-Tang; Wu, Shang-Rung; Yin, Ji-Hang; Liao, Jiunn-Wang; Chang, Gwong-Jen J; Chiou, Shyan-Song

    2018-05-10

    Swine are a critical amplifying host involved in human Japanese encephalitis (JE) outbreaks. Cross-genotypic immunogenicity and sterile protection are important for the current genotype III (GIII) virus-derived vaccines in swine, especially now that emerging genotype I (GI) JE virus (JEV) has replaced GIII virus as the dominant strain. Herein, we aimed to develop a system to generate GI JEV virus-like particles (VLPs) and evaluate the immunogenicity and protection of the GI vaccine candidate in mice and specific pathogen-free swine. A CHO-heparan sulfate-deficient (CHO-HS(-)) cell clone, named 51-10 clone, stably expressing GI-JEV VLP was selected and continually secreted GI VLPs without signs of cell fusion. 51-10 VLPs formed a homogeneously empty-particle morphology and exhibited similar antigenic activity as GI virus. GI VLP-immunized mice showed balanced cross-neutralizing antibody titers against GI to GIV viruses (50% focus-reduction micro-neutralization assay titers 71 to 240) as well as potent protection against GI or GIII virus infection. GI VLP-immunized swine challenged with GI or GIII viruses showed no fever, viremia, or viral RNA in tonsils, lymph nodes, and brains as compared with phosphate buffered saline-immunized swine. We thus conclude GI VLPs can provide sterile protection against GI and GIII viruses in swine.

  19. Piezoelectrically forced vibrations of rectangular SC-cut quartz plates

    NASA Astrophysics Data System (ADS)

    Lee, P. C. Y.; Lin, W. S.

    1998-06-01

    A system of two-dimensional first-order equations for piezoelectric crystal plates with general symmetry and with electroded faces was recently deduced from the three-dimensional equations of linear piezoelectricity. Solutions of these equations for AT-cut plates of quartz were shown to give accurate dispersion curves without corrections, and the resonances predicted agree closely with the experimental data of Koga and Fukuyo [I. Koga and H. Fukuyo, J. Inst. Electr. Commun. Eng. Jpn. 36, 59 (1953)] and that of Nakazawa, Horiuchi, and Ito (M. Nakazawa, K. Horiuchi, and H. Ito, Proceedings of the 1990 IEEE Ultrasonics Symposium, pp. 547-555). In this article, these equations are employed to study the free as well as the forced vibrations of doubly rotated quartz plates. Solutions of straight-crested vibrational modes varying in the x1 and x3 directions of SC-cut quartz plates of infinite extent are obtained and from which dispersion curves are computed. Comparison of those dispersion curves with those from the three-dimensional equations shows that the agreement is very close without any corrections. Resonance frequencies for free vibrations and capacitance ratios for piezoelectrically forced vibrations are computed and examined for various length-to-thickness or width-to-thickness ratios of rectangular SC-cut quartz plates. The capacitance ratio as a function of forcing frequency is computed for a rectangular AT-cut quartz and compared with the experimental data of Seikimoto, Watanabe, and Nakazawa (H. Sekimoto, Y. Watanabe, and M. Nakazawa, Proceedings of the 1992 IEEE Frequency Control Symposium, pp. 532-536) and is in close agreement.

  20. Comparison of eigensolvers for symmetric band matrices.

    PubMed

    Moldaschl, Michael; Gansterer, Wilfried N

    2014-09-15

    We compare different algorithms for computing eigenvalues and eigenvectors of a symmetric band matrix across a wide range of synthetic test problems. Of particular interest is a comparison of state-of-the-art tridiagonalization-based methods as implemented in Lapack or Plasma on the one hand, and the block divide-and-conquer (BD&C) algorithm as well as the block twisted factorization (BTF) method on the other hand. The BD&C algorithm does not require tridiagonalization of the original band matrix at all, and the current version of the BTF method tridiagonalizes the original band matrix only for computing the eigenvalues. Avoiding the tridiagonalization process sidesteps the cost of backtransformation of the eigenvectors. Beyond that, we discovered another disadvantage of the backtransformation process for band matrices: In several scenarios, a lot of gradual underflow is observed in the (optional) accumulation of the transformation matrix and in the (obligatory) backtransformation step. According to the IEEE 754 standard for floating-point arithmetic, this implies many operations with subnormal (denormalized) numbers, which causes severe slowdowns compared to the other algorithms without backtransformation of the eigenvectors. We illustrate that in these cases the performance of existing methods from Lapack and Plasma reaches a competitive level only if subnormal numbers are disabled (and thus the IEEE standard is violated). Overall, our performance studies illustrate that if the problem size is large enough relative to the bandwidth, BD&C tends to achieve the highest performance of all methods if the spectrum to be computed is clustered. For test problems with well separated eigenvalues, the BTF method tends to become the fastest algorithm with growing problem size.

  1. Clinicopathological and Prognostic Analysis of Primary Gastrointestinal Stromal Tumor Presenting with Gastrointestinal Bleeding: a 10-Year Retrospective Study.

    PubMed

    Yin, Zhijie; Gao, Jinbo; Liu, Weizhen; Huang, Cheng; Shuai, Xiaoming; Wang, Guobin; Tao, Kaixiong; Zhang, Peng

    2017-05-01

    The objectives of this paper were to investigate the clinicopathological characteristics and prognostic factors of GI-bleeding GIST patients and explore whether GI bleeding is a risk factor for GIST relapse. Primary GIST patients with initial symptoms of GI bleeding or no GI bleeding were retrospectively studied. Up to 178 GI-bleeding GIST patients including 108 (60.7%) males and 70 (39.3%) females were evaluated for the clinicopathological characteristics. The stomach, small bowel, and colorectum were the tumor sites in 82 (46.1%), 85 (47.8%), and 11 (6.2%) patients. Of the 178 patients, 163 GI-bleeding patients had follow-up while another 363 patients from the total population presented without GI bleeding were followed up. Up to 526 patients who received postoperative follow-up were included in the survival analysis. Compared with the 363 non-GI-bleeding patients, GI-bleeding patients developed smaller tumors (P = 0.015) and had a longer relapse-free survival (RFS; P = 0.014). For the 163 GI-bleeding patients, a Cox regression analysis showed that the mitotic count and the platelet-lymphocyte ratio before surgery were independent prognostic predictors for poor outcome regarding RFS. For all 526 patients, a Cox regression analysis indicated that tumor location, mitotic index, platelet-lymphocyte ratio, and GI bleeding were independent prognosis predictors. Compared to non-GI-bleeding GIST patients, patients with GI bleeding were more likely to be male and to have more small intestine GISTs, smaller tumors, and a longer RFS. For GI-bleeding patients, mitotic count and platelet-lymphocyte ratio were independent prognostic indicators. GI bleeding served as a surrogate for smaller GIST and was a protective factor for GIST recurrence.

  2. Clinical Toxicities and Dosimetric Parameters After Whole-Pelvis Versus Prostate-Only Intensity-Modulated Radiation Therapy for Prostate Cancer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Deville, Curtiland, E-mail: deville@uphs.upenn.ed; Both, Stefan; Hwang, Wei-Ting

    2010-11-01

    Purpose: To assess whether whole-pelvis (WP) intensity-modulated radiation therapy (IMRT) is associated with increased toxicity compared with prostate-only (PO) IMRT. Methods and Materials: We retrospectively analyzed all patients with prostate cancer undergoing definitive IMRT to 79.2 Gy with concurrent androgen deprivation at our institution from November 2005 to May 2007 with a minimum follow-up of 12 months. Thirty patients received initial WP IMRT to 45 Gy in 1.8-Gy fractions, and thirty patients received PO IMRT. Study patients underwent computed tomography simulation and treatment planning by use of predefined dose constraints. Bladder and rectal dose-volume histograms, maximum genitourinary (GU) and gastrointestinalmore » (GI) Radiation Therapy Oncology Group toxicity grade, and late Grade 2 or greater toxicity-free survival curves were compared between the two groups by use of the Student t test, Fisher exact test, and Kaplan-Meier curve, respectively. Results: Bladder minimum dose, mean dose, median dose, volume receiving 5 Gy, volume receiving 20 Gy, volume receiving 40 Gy, and volume receiving 45 Gy and rectal minimum dose, median dose, and volume receiving 20 Gy were significantly increased in the WP group (all p values < 0.01). Maximum acute GI toxicity was limited to Grade 2 and was significantly increased in the WP group at 50% vs. 13% the PO group (p = 0.006). With a median follow-up of 24 months (range, 12-35 months), there was no difference in late GI toxicity (p = 0.884) or in acute or late GU toxicity. Conclusions: Despite dosimetric differences in the volume of bowel, bladder, and rectum irradiated in the low-dose and median-dose regions, WP IMRT results only in a clinically significant increase in acute GI toxicity, in comparison to PO IMRT, with no difference in GU or late GI toxicity.« less

  3. David Mooney | NREL

    Science.gov Websites

    : Institute of Electrical and Electronics Engineers (IEEE). NREL/CP-5500-54165. doi:10.1109/EnergyTech 2011. Piscataway, NJ: Institute of Electrical and Electronics Engineers (IEEE). NREL/CP-5500-53565. doi Electrical and Electronics Engineers (IEEE). NREL/CP-550-47061. doi:10.1109/pes.2009.5275358 Mooney, D., M

  4. Novel Low Cost High Efficiency Tunable RF Devices and Antenna Arrays Design based on the Ferroelectric Materials and the CTS Technologies

    DTIC Science & Technology

    2011-02-14

    licensed use limited to: UNIV OF HAWAII LIBRARY. Downloaded on June 18,2010 at 22:24:49 UTC from IEEE Xplore . Restrictions apply. KIM et al.: MODIFIED...limited to: UNIV OF HAWAII LIBRARY. Downloaded on June 18,2010 at 22:24:49 UTC from IEEE Xplore . Restrictions apply. 404 IEEE TRANSACTIONS ON...licensed use limited to: UNIV OF HAWAII LIBRARY. Downloaded on June 18,2010 at 22:24:49 UTC from IEEE Xplore . Restrictions apply. KIM et al

  5. Robust Pressure-Actuated Liquid Metal Devices Showing Reconfigurable Electromagnetic Effects at GHz Frequencies (POSTPRINT)

    DTIC Science & Technology

    2014-06-01

    IEEE Xplore , 978-1-4799-3540-6/14, pages 553-554. © 2014 IEEE . The U.S. Government is joint author of the work and has the right to use, modify...unlimited. See additional restrictions described on inside pages STINFO COPY © 2014 IEEE AIR FORCE RESEARCH LABORATORY MATERIALS AND...AR Brown-US, 3M101200250). The length of the dipole arms are changed via 553978-1-4799-3540-6/14/$31.00 ©2014 IEEE AP-S 2014 1 Distribution A

  6. Evaluating compliance to a low glycaemic index (GI) diet in women with polycystic ovary syndrome (PCOS).

    PubMed

    Egan, Nicola; Read, Anna; Riley, Paddy; Atiomo, William

    2011-03-08

    A low Glycaemic Index (GI) diet may decrease some long-term health risks in Polycystic Ovary Syndrome (PCOS) such as endometrial cancer. This study was performed to assess compliance to a low GI diet in women with PCOS. Food diaries prospectively collected over 6 months from women on a low GI diet or healthy eating diet were analysed retrospectively. The women were recruited for a pilot randomised control trial investigating whether a low GI diet decreased the risk of Endometrial Cancer. Nine women with PCOS completed 33 food diaries (17 from women on a low GI diet and 16 from women on a healthy eating diet) recording 3023 food items (low GI group:n = 1457; healthy eating group:n = 1566). Data was analysed using Foster-Powell international values inserted into an SPSS database as no scientifically valid established nutrition software was found. The main outcome measures were mean item GI and Glyacemic Load (GL), mean meal GL, percentage high GI foods and mean weight loss. Women allocated the low GI diet had a statistically significant lower GI of food items (33.67 vs 36.91, p < 0.05), lower percentage of high GI foods (4.3% vs 12.1%, p < 0.05) and lower GL of food items and meals. Women with PCOS on a low GI diet consumed food items with a significantly lower mean GI and GL compared to the healthy eating diet group. Longer term compliance needs evaluation in subsequent studies to ascertain that this translates to reduced long term health risks. ISRCTN: ISRCTN86420258.

  7. Mixed-mode cyclic debonding of adhesively bonded composite joints. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Rezaizadeh, M. A.; Mall, S.

    1985-01-01

    A combined experimental-analytical investigation to characterize the cyclic failure mechanism of a simple composite-to-composite bonded joint is conducted. The cracked lap shear (CLS) specimens of graphite/epoxy adherend bonded with EC-3445 adhesive are tested under combined mode 1 and 2 loading. In all specimens tested, fatigue failure occurs in the form of cyclic debonding. The cyclic debond growth rates are measured. The finite element analysis is employed to compute the mode 1, mode 2, and total strain energy release rates (i.e., GI, GII, and GT). A wide range of mixed-mode loading, i.e., GI/GII ranging from 0.03 to 0.38, is obtained. The total strain energy release rate, G sub T, appeared to be the driving parameter for cyclic debonding in the tested composite bonded system.

  8. Barium enema

    MedlinePlus

    Lower gastrointestinal series; Lower GI series; Colorectal cancer - lower GI series; Colorectal cancer - barium enema; Crohn disease - lower GI series; Crohn disease - barium enema; Intestinal blockage - lower GI series; Intestinal ...

  9. Gastrointestinal bleeding after intracerebral hemorrhage: a retrospective review of 808 cases.

    PubMed

    Yang, Tie-Cheng; Li, Jian-Guo; Shi, Hong-Mei; Yu, Dong-Ming; Shan, Kai; Li, Li-Xia; Dong, Xiao-Yan; Ren, Tian-Hua

    2013-10-01

    This study examined the incidence and risk factors for gastrointestinal (GI) bleeding after spontaneous intracerebral hemorrhage (ICH). The available medical records of patients with ICH admitted from June 2008 to December 2009 for any episode of GI bleeding, possible precipitating factors and administration of ulcer prophylaxis were reviewed. The prevalence of GI bleeding was 26.7%, including 3 cases of severe GI bleeding (0.35%). Patients with GI bleeding had significantly longer hospital stay and higher in-hospital mortality compared with patients without GI bleeding. Multivariate logistic regression analyses showed that age, Glasgow Coma Scale scores, sepsis and ICH volume were independent predictors of GI bleeding. About 63.4% of patients with ICH received stress ulcer prophylaxis. GI bleeding occurred frequently after ICH, but severe events were rare. Age, Glasgow Coma Scale score, sepsis and ICH volume were independent predictors of GI bleeding occurring after ICH.

  10. Gastrointestinal Physiology and Function.

    PubMed

    Greenwood-Van Meerveld, Beverley; Johnson, Anthony C; Grundy, David

    2017-01-01

    The gastrointestinal (GI) system is responsible for the digestion and absorption of ingested food and liquids. Due to the complexity of the GI tract and the substantial volume of material that could be covered under the scope of GI physiology, this chapter briefly reviews the overall function of the GI tract, and discusses the major factors affecting GI physiology and function, including the intestinal microbiota, chronic stress, inflammation, and aging with a focus on the neural regulation of the GI tract and an emphasis on basic brain-gut interactions that serve to modulate the GI tract. GI diseases refer to diseases of the esophagus, stomach, small intestine, colon, and rectum. The major symptoms of common GI disorders include recurrent abdominal pain and bloating, heartburn, indigestion/dyspepsia, nausea and vomiting, diarrhea, and constipation. GI disorders rank among the most prevalent disorders, with the most common including esophageal and swallowing disorders, gastric and peptic ulcer disease, gastroparesis or delayed gastric emptying, irritable bowel syndrome (IBS), and inflammatory bowel disease (IBD). Many GI disorders are difficult to diagnose and their symptoms are not effectively managed. Thus, basic research is required to drive the development of novel therapeutics which are urgently needed. One approach is to enhance our understanding of gut physiology and pathophysiology especially as it relates to gut-brain communications since they have clinical relevance to a number of GI complaints and represent a therapeutic target for the treatment of conditions including inflammatory diseases of the GI tract such as IBD and functional gut disorders such as IBS.

  11. Contract W911NF-09-1-0488 (Rush University Medical Center)

    DTIC Science & Technology

    2012-11-23

    algorithm. In Proceedings of the 1993 ACM/IEEE Conference on Supercomputing, pages 12�21, New York, 1993. ACM. [8] R. Yokota, T. Hamada, J. P. Bardhan , M...computing gravity anom- alies. Geophysical Journal International, 2011. to appear. [13] R. Yokota, T. Hamada, J. P. Bardhan , M. G. Knepley, and L. A. Barba...extension of the petfmm a fast multipole library. Presentation at WCCM 2010, Sydney Australia, 2010. [15] J. P. Bardhan . Interpreting the Coulomb

  12. Performance Evaluation and Control of Distributed Computer Communication Networks.

    DTIC Science & Technology

    1984-09-01

    including: L. Clare, L.A. De Moraes, J. Baker, M. Zuckerman, S. Katz, P. Rodrigues, R. Pazos , S. Resheff. Other participants are the following visiting...investigations have been reported in reference (1) and (2) below. References (1) M. Gerla, R. Pazos -Rangel "Bandwidth Allocation and Routing in ISDN’s," IEEE...and efficient methods for its solution are presented. (2) R.A. Pazos -Rangel "Evaluation and Design of Integrated Packet Switching and Circuit Switching

  13. Solving Variational Problems and Partial Differential Equations Mapping into General Target Manifolds

    DTIC Science & Technology

    2002-01-01

    1998. [36] T. Sakai, Riemannian Geometry, AMS Translations of Mathematical Monographs, vol 149. [37] N. Sochen, R . Kimmel, and R , Malladi , “A general...matical Physics 107, pp. 649-705, 1986. [5] V. Caselles, R . Kimmel, G. Sapiro, and C. Sbert, “Minimal surfaces based object segmentation,” IEEE- PAMI...June 2000 [9] R . Cohen, R . M. Hardt, D. Kinderlehrer, S. Y. Lin, and M. Luskin, “Minimum energy configurations for liquid crystals: Computational

  14. Design and Implementation of the MARG Human Body Motion Tracking System

    DTIC Science & Technology

    2004-10-01

    7803-8463-6/041$20.00 ©:!004 IEEE 625 OPTOTRAK from Northern Digital Inc. is a typical example of a marker-based system [I 0]. Another is the...technique called tunneling is :used to overcome this problem. Tunneling is a software solution that runs on the end point routers/computers and allows...multicast packets to traverse the network by putting them into unicast packets. MUTUP overcomes the tunneling problem using shared memory in the

  15. Pseudorandom Number Generators for Mobile Devices: An Examination and Attempt to Improve Randomness

    DTIC Science & Technology

    2013-09-01

    Notes in Computer Science (LNCS), Vol. 4341), (Hanoi, Vietnam: Springer, 2006), 260–270. 36 Simon R. Blackburn , “The Linear Complexity of the Self... Blackburn , Simon R. ‘The Linear Complexity of the Self-Shrinking Generator.” IEEE Trans. Inf. Theory, 45 (September 1999). Blum, Leonore, Manuel...afloat when the waters have been rough! xv THIS PAGE INTENTIONALLY LEFT BLANK xvi I. INTRODUCTION When the average man thinks about war and

  16. Access Point Selection for Multi-Rate IEEE 802.11 Wireless LANs

    DTIC Science & Technology

    2014-05-16

    Mobile Systems, Applications and Services, 2006. [2] S . Vasudevan, K. Papagiannaki, C . Diot, J. Kurose, and D. Towsley, “Facilitating Access Point...LANs 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7...PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) University of California at Berkeley,Electrical Engineering and Computer Sciences,Berkeley,CA,94720 8

  17. Galileo battery testing and the impact of test automation

    NASA Technical Reports Server (NTRS)

    Pertuch, W. T.; Dils, C. T.

    1985-01-01

    Test complexity, changes of test specifications, and the demand for tight control of tests led to the development of automated testing used for Galileo and other projects. The use of standardized interfacing, i.e., IEEE-488, with desktop computers and test instruments, resulted in greater reliability, repeatability, and accuracy of both control and data reporting. Increased flexibility of test programming has reduced costs by permitting a wide spectrum of test requirements at one station rather than many stations.

  18. Statistical and Variational Methods for Problems in Visual Control

    DTIC Science & Technology

    2009-03-02

    plane curves to round points," /. Differential Geometry 26 (1987), pp. 285-314. 12 [7] S. Haker , G. Sapiro, and A. Tannenbaum, "Knowledge-based...segmentation of SAR data with learned priors," IEEE Trans. Image Processing, vol. 9, pp. 298-302, 2000. [8] S. Haker , L. Zhu, S. Angenent, and A...Tannenbaum, "Optimal mass transport for registration and warping" Int. Journal Computer Vision, vol. 60, pp. 225-240, 2004. [9] S. Haker , G. Sapiro, A

  19. Chemistry and Physics of Analyte Identification in Integrated Nanosensors

    DTIC Science & Technology

    2009-02-05

    points," / Differential Geometry 26 (1987), pp. 285-314. 12 [7] S. Haker , G. Sapiro, and A. Tannenbaum, "Knowledge-based segmentation of SAR data with...learned priors," IEEE Trans. Image Processing, vol. 9, pp. 298-302, 2000. [8] S. Haker , L. Zhu, S. Angenent, and A. Tannenbaum, "Optimal mass...transport for registration and warping" Int. Journal Computer Vision, vol. 60, pp. 225-240, 2004. [9] S. Haker , G. Sapiro, A. Tannenbaum, and D. Washburn

  20. A Decision Support System for Control and Automation of Dynamical Processes

    DTIC Science & Technology

    1990-03-01

    would like to thank my Advisor, Asok Ray , for giving me the opportunity to become involved in the Artificial Intelligence field, and for his guidance in...Applications, IEEE Computer Society, December 1984, pp 460-464. 76 [Ray87) Ray , A., Joshi, S. M., Whitney, C. K., Jow, H. N., "Information...Thomp88] Thompson, D. R., Ray , A., Kumara, S., "A Hierarchically Structured Knowledge-Based System for Welding Automation and Control", Journal of

  1. GLOBECOM '92 - IEEE Global Telecommunications Conference, Orlando, FL, Dec. 6-9, 1992, Conference Record. Vols. 1-3

    NASA Astrophysics Data System (ADS)

    Papers are presented on such topics as the wireless data network in PCS, advances in digital mobile networks, ATM switching experiments, broadband applications, network planning, and advances in SONET/SDH implementations. Consideration is also given to gigabit computer networks, techniques for modeling large high-speed networks, coding and modulation, the next-generation lightwave system, signaling systems for broadband ISDN, satellite technologies, and advances in standardization of low-rate signal processing.

  2. Product plots.

    PubMed

    Wickham, Hadley; Hofmann, Heike

    2011-12-01

    We propose a new framework for visualising tables of counts, proportions and probabilities. We call our framework product plots, alluding to the computation of area as a product of height and width, and the statistical concept of generating a joint distribution from the product of conditional and marginal distributions. The framework, with extensions, is sufficient to encompass over 20 visualisations previously described in fields of statistical graphics and infovis, including bar charts, mosaic plots, treemaps, equal area plots and fluctuation diagrams. © 2011 IEEE

  3. Joint Services Electronics Program.

    DTIC Science & Technology

    1986-09-30

    IEEE Computer Society Conference on Trends and Aplications , Gaithersburg, MD, 57-62, May 1983. R.W. Miksad, D.W. Choi and E.J. Powers, "Application of...Estimators for Weakl Nonlinear Esti’mation Problems, M.S. Thesis , Dept. of Electrica Engineering, University of Texas at Austin, May 1982. 7 %- (Page...Chen, J. Vac. Sci. Technol. 17,911 (1980). 6. N.I. Cho, Masters Thesis , unpublished. 7. EI-Saied M. Aly and J.P. Stark, J. Appl. Phys. 53(4), 3063

  4. IEEE Computer Society/Software Engineering Institute Watts S. Humphrey Software Process Achievement (SPA) Award 2016: Nationwide

    DTIC Science & Technology

    2017-04-05

    Information Technology at Nationwide v Abstract vi 1 Business Imperatives 1 1.1 Deliver the Right Work 1 1.2 Deliver the Right Way 1 1.3 Deliver with...an Engaged Workforce 1 2 Challenges and Opportunities 2 2.1 Responding to Demand 2 2.2 Standards and Capabilities 2 2.3 Information Technology ...release and unlimited distribution. Information Technology at Nationwide Nationwide Information Technology (IT) is comprised of seven offices

  5. United States Air Force Summer Research Program -- 1993. Volume 1. Program Management Report

    DTIC Science & Technology

    1993-12-01

    IEEE Spectrum and Physics Today. High school applicants can participate only in laboratories located no more than 20 miles from their residence. Tailored...faculty and $37/day for graduate students whose homes were more than 50 miles from the laboratory. Transportation to the laboratory at the beginning of...TX 78212- 7200 Branting, Luther Field: Dept of Computer Science Assistant Professor, PhD Laboratory: AL/HR PC Box 3682 University of Wyoming Vol-Page

  6. libvaxdata: VAX data format conversion routines

    USGS Publications Warehouse

    Baker, Lawrence M.

    2005-01-01

    libvaxdata provides a collection of routines for converting numeric data-integer and floating-point-to and from the formats used on a Digital Equipment Corporation1 (DEC) VAX 32-bit minicomputer (Brunner, 1991). Since the VAX numeric data formats are inherited from those used on a DEC PDP-11 16-bit minicomputer, these routines can be used to convert PDP-11 data as well. VAX numeric data formats are also the default data formats used on DEC Alpha 64-bit minicomputers running OpenVMS The libvaxdata routines are callable from Fortran or C. They require that the caller use two's-complement format for integer data and IEEE 754 format (ANSI/IEEE, 1985) for floating-point data. They also require that the 'natural' size of a C int type (integer) is 32 bits. That is the case for most modern 32-bit and 64-bit computer systems. Nevertheless, you may wish to consult the Fortran or C compiler documentation on your system to be sure. Some Fortran compilers support conversion of VAX numeric data on-the-fly when reading or writing unformatted files, either as a compiler option or a run-time I/O option. This feature may be easier to use than the libvaxdata routines. Consult the Fortran compiler documentation on your system to determine if this alternative is available to you. 1Later Compaq Computer Corporation, now Hewlett-Packard Company

  7. Expression and characterization of duck enteritis virus gI gene

    PubMed Central

    2011-01-01

    Background At present, alphaherpesviruses gI gene and its encoding protein have been extensively studied. It is likely that gI protein and its homolog play similar roles in virions direct cell-to-cell spread of alphaherpesviruses. But, little is known about the characteristics of DEV gI gene. In this study, we expressed and presented the basic properties of the DEV gI protein. Results The special 1221-bp fragment containing complete open reading frame(ORF) of duck enteritis virus(DEV) gI gene was extracted from plasmid pMD18-T-gI, and then cloned into prokaryotic expression vector pET-32a(+), resulting in pET-32a(+)-gI. After being confirmed by PCR, restriction endonuclease digestion and sequencing, pET-32a(+)-gI was transformed into E.coli BL21(DE3) competent cells for overexpression. DEV gI gene was successfully expressed by the addition of isopropyl-β-D-thiogalactopyranoside(IPTG). SDS-PAGE showed that the recombinant protein His6-tagged gI molecular weight was about 61 kDa. Subsequently, the expressed product was applied to generate specific antibody against gI protein. The specificity of the rabbit immuneserum was confirmed by its ability to react with the recombinant protein His6-tagged gI. In addition, real time-PCR was used to determine the the levels of the mRNA transcripts of gI gene, the results showed that the DEV gI gene was transcribed most abundantly during the late phase of infection. Furthermore, indirect immunofluorescence(IIF) was established to study the gI protein expression and localization in DEV-infected duck embryo fibroblasts (DEFs), the results confirmed that the protein was expressed and located in the cytoplasm of the infected cells, intensively. Conclusions The recombinant prokaryotic expression vector of DEV gI gene was constructed successfully. The gI protein was successfully expressed by E.coli BL21(DE3) and maintained its antigenicity very well. The basic information of the transcription and intracellular localization of gI gene were presented, that would be helpful to assess the possible role of DEV gI gene. The research will provide useful clues for further functional analysis of DEV gI gene. PMID:21595918

  8. Trends in Device SEE Susceptibility from Heavy Ions

    NASA Technical Reports Server (NTRS)

    Nichols, D. K.; Coss, J. R.; McCarty, K. P.; Schwartz, H. R.; Swift, G. M.; Watson, R. K.; Koga, R.; Crain, W. R.; Crawford, K. B.; Hansel, S. J.

    1995-01-01

    The sixth set of heavy ion single event effects (SEE) test data have been collected since the last IEEE publications in December issues of IEEE - Nuclear Science Transactions for 1985, 1987, 1989, 1991, and the IEEE Workshop Record, 1993. Trends in SEE susceptibility (including soft errors and latchup) for state-of- are evaluated.

  9. Green Infrastructure Increases Biogeochemical Responsiveness, Vegetation Growth and Decreases Runoff in a Semi-Arid City, Tucson, AZ, USA

    NASA Astrophysics Data System (ADS)

    Meixner, T.; Papuga, S. A.; Luketich, A. M.; Rockhill, T.; Gallo, E. L.; Anderson, J.; Salgado, L.; Pope, K.; Gupta, N.; Korgaonkar, Y.; Guertin, D. P.

    2017-12-01

    Green Infrastructure (GI) is often viewed as a mechanism to minimize the effects of urbanization on hydrology, water quality, and other ecosystem services (including the urban heat island). Quantifying the effects of GI requires field measurements of the dimensions of biogeochemical, ecosystem, and hydrologic function that we expect GI to impact. Here we investigated the effect of GI features in Tucson, Arizona which has a low intensity winter precipitation regime and a high intensity summer regime. We focused on understanding the effect of GI on soil hydraulic and biogeochemical properties as well as the effect on vegetation and canopy temperature. Our results demonstrate profound changes in biogeochemical and hydrologic properties and vegetation growth between GI systems and nearby control sites. In terms of hydrologic properties GI soils had increased water holding capacity and hydraulic conductivity. GI soils also have higher total carbon, total nitrogen, and organic matter in general than control soils. Furthermore, we tested the sampled soils (control and GI) for differences in biogeochemical response upon wetting. GI soils had larger respiration responses indicating greater biogeochemical activity overall. Long-term Lidar surveys were used to investigate the differential canopy growth of GI systems versus control sites. The results of this analysis indicate that while a significant amount of time is needed to observe differences in canopy growth GI features due increase tree size and thus likely impact street scale ambient temperatures. Additionally monitoring of transpiration, soil moisture, and canopy temperature demonstrates that GI features increase vegetation growth and transpiration and reduce canopy temperatures. These biogeochemical and ecohydrologic results indicate that GI can increase the biogeochemical processing of soils and increase tree growth and thus reduce urban ambient temperatures.

  10. Effects of long-term intervention with low- and high-glycaemic-index breakfasts on food intake in children aged 8-11 years.

    PubMed

    Henry, C Jeya K; Lightowler, Helen J; Strik, Caroline M

    2007-09-01

    The aim of the present study was to investigate the effects of long-term intervention of low-glycaemic-index (GI) v. high-GI breakfasts on energy and macronutrient intakes in children aged 8-11 years. Preadolescent children were assigned to one of two groups in a random cross-over design. Each group was given low-GI and high-GI breakfasts on two non-consecutive days per week for 10 weeks per breakfast type. Each breakfast provided approximately 1273 kJ (300 kcal) and was closely matched for macronutrient and dietary fibre content. Subsequent food intake at an ad libitum buffet lunch was recorded and daily energy and macronutrient intakes were measured by 24 h recall and 3 d food diaries. There was a tendency towards a reduced energy intake at lunch following the low-GI breakfast compared with the high-GI breakfast, although the mean difference of 75 kJ (18 kcal) was not significant (P = 0.406). In particular, there was a trend towards a reduced energy intake in the low-GI arm compared with the high-GI arm among boys. In addition, data from the 3 d food diaries showed that there was a tendency towards a reduced energy intake during the low-GI compared with the high-GI study period. In conclusion, although the difference in energy intake following the low-GI and high-GI breakfasts was not statistically significant, the reduced energy intake following the low-GI breakfast is encouraging. Both dietary fibre and carbohydrate type may affect GI, thus their potential and relative modulating effect on appetite requires further investigation.

  11. Precision of EM Simulation Based Wireless Location Estimation in Multi-Sensor Capsule Endoscopy

    PubMed Central

    Ye, Yunxing; Aisha, Ain-Ul; Swar, Pranay; Pahlavan, Kaveh

    2018-01-01

    In this paper, we compute and examine two-way localization limits for an RF endoscopy pill as it passes through an individuals gastrointestinal (GI) tract. We obtain finite-difference time-domain and finite element method-based simulation results position assessment employing time of arrival (TOA). By means of a 3-D human body representation from a full-wave simulation software and lognormal models for TOA propagation from implant organs to body surface, we calculate bounds on location estimators in three digestive organs: stomach, small intestine, and large intestine. We present an investigation of the causes influencing localization precision, consisting of a range of organ properties; peripheral sensor array arrangements, number of pills in cooperation, and the random variations in transmit power of sensor nodes. We also perform a localization precision investigation for the situation where the transmission signal of the antenna is arbitrary with a known probability distribution. The computational solver outcome shows that the number of receiver antennas on the exterior of the body has higher impact on the precision of the location than the amount of capsules in collaboration within the GI region. The large intestine is influenced the most by the transmitter power probability distribution. PMID:29651364

  12. Precision of EM Simulation Based Wireless Location Estimation in Multi-Sensor Capsule Endoscopy.

    PubMed

    Khan, Umair; Ye, Yunxing; Aisha, Ain-Ul; Swar, Pranay; Pahlavan, Kaveh

    2018-01-01

    In this paper, we compute and examine two-way localization limits for an RF endoscopy pill as it passes through an individuals gastrointestinal (GI) tract. We obtain finite-difference time-domain and finite element method-based simulation results position assessment employing time of arrival (TOA). By means of a 3-D human body representation from a full-wave simulation software and lognormal models for TOA propagation from implant organs to body surface, we calculate bounds on location estimators in three digestive organs: stomach, small intestine, and large intestine. We present an investigation of the causes influencing localization precision, consisting of a range of organ properties; peripheral sensor array arrangements, number of pills in cooperation, and the random variations in transmit power of sensor nodes. We also perform a localization precision investigation for the situation where the transmission signal of the antenna is arbitrary with a known probability distribution. The computational solver outcome shows that the number of receiver antennas on the exterior of the body has higher impact on the precision of the location than the amount of capsules in collaboration within the GI region. The large intestine is influenced the most by the transmitter power probability distribution.

  13. National estimates of hospital utilization by children with gastrointestinal disorders: analysis of the 1997 kids' inpatient database.

    PubMed

    Guthery, Stephen L; Hutchings, Caroline; Dean, J Michael; Hoff, Charles

    2004-05-01

    To identify and to generate national estimates of the principal gastrointestinal (GI) diagnoses associated with hospital utilization and to describe national hospital utilization patterns associated with pediatric GI disorders. We analyzed a nationwide and stratified probability sample of 1.9 million hospital discharges from 1997 of children 18 years and younger, weighted to 6.7 million discharges nationally. Principal GI diagnoses were identified through the use of the Clinical Classification Software and Major Diagnostic Categories. In 1997 in the United States, there were 329,825 pediatric discharges associated with a principal GI diagnosis, accounting for more than 2.6 billion US dollars in hospital charges and more than 1.1 million hospital days. Appendicitis, intestinal infection, noninfectious gastroenteritis, abdominal pain, esophageal disorders, and digestive congenital anomalies combined accounted for 75.1% of GI discharge diagnoses, 64.2% of GI hospital charges, and 68.0% of GI hospital days. Excluding normal newborn infants and conditions related to pregnancy, GI disorders were the third leading cause of hospitalization. GI disorders are a leading cause of hospitalization of children. A minority of GI conditions account for the majority of measures of utilization. Children are hospitalized for GI conditions and at institutions that are distinct from adults.

  14. Adding glycaemic index and glycaemic load functionality to DietPLUS, a Malaysian food composition database and diet intake calculator.

    PubMed

    Shyam, Sangeetha; Wai, Tony Ng Kock; Arshad, Fatimah

    2012-01-01

    This paper outlines the methodology to add glycaemic index (GI) and glycaemic load (GL) functionality to food DietPLUS, a Microsoft Excel-based Malaysian food composition database and diet intake calculator. Locally determined GI values and published international GI databases were used as the source of GI values. Previously published methodology for GI value assignment was modified to add GI and GL calculators to the database. Two popular local low GI foods were added to the DietPLUS database, bringing up the total number of foods in the database to 838 foods. Overall, in relation to the 539 major carbohydrate foods in the Malaysian Food Composition Database, 243 (45%) food items had local Malaysian values or were directly matched to International GI database and another 180 (33%) of the foods were linked to closely-related foods in the GI databases used. The mean ± SD dietary GI and GL of the dietary intake of 63 women with previous gestational diabetes mellitus, calculated using DietPLUS version3 were, 62 ± 6 and 142 ± 45, respectively. These values were comparable to those reported from other local studies. DietPLUS version3, a simple Microsoft Excel-based programme aids calculation of diet GI and GL for Malaysian diets based on food records.

  15. An Overview of High Performance Computing and Challenges for the Future

    ScienceCinema

    Google Tech Talks

    2017-12-09

    In this talk we examine how high performance computing has changed over the last 10-year and look toward the future in terms of trends. These changes have had and will continue to have a major impact on our software. A new generation of software libraries and lgorithms are needed for the effective and reliable use of (wide area) dynamic, distributed and parallel environments. Some of the software and algorithm challenges have already been encountered, such as management of communication and memory hierarchies through a combination of compile--time and run--time techniques, but the increased scale of computation, depth of memory hierarchies, range of latencies, and increased run--time environment variability will make these problems much harder. We will focus on the redesign of software to fit multicore architectures. Speaker: Jack Dongarra University of Tennessee Oak Ridge National Laboratory University of Manchester Jack Dongarra received a Bachelor of Science in Mathematics from Chicago State University in 1972 and a Master of Science in Computer Science from the Illinois Institute of Technology in 1973. He received his Ph.D. in Applied Mathematics from the University of New Mexico in 1980. He worked at the Argonne National Laboratory until 1989, becoming a senior scientist. He now holds an appointment as University Distinguished Professor of Computer Science in the Electrical Engineering and Computer Science Department at the University of Tennessee, has the position of a Distinguished Research Staff member in the Computer Science and Mathematics Division at Oak Ridge National Laboratory (ORNL), Turing Fellow in the Computer Science and Mathematics Schools at the University of Manchester, and an Adjunct Professor in the Computer Science Department at Rice University. He specializes in numerical algorithms in linear algebra, parallel computing, the use of advanced-computer architectures, programming methodology, and tools for parallel computers. His research includes the development, testing and documentation of high quality mathematical software. He has contributed to the design and implementation of the following open source software packages and systems: EISPACK, LINPACK, the BLAS, LAPACK, ScaLAPACK, Netlib, PVM, MPI, NetSolve, Top500, ATLAS, and PAPI. He has published approximately 200 articles, papers, reports and technical memoranda and he is coauthor of several books. He was awarded the IEEE Sid Fernbach Award in 2004 for his contributions in the application of high performance computers using innovative approaches. He is a Fellow of the AAAS, ACM, and the IEEE and a member of the National Academy of Engineering.

  16. An Overview of High Performance Computing and Challenges for the Future

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Google Tech Talks

    In this talk we examine how high performance computing has changed over the last 10-year and look toward the future in terms of trends. These changes have had and will continue to have a major impact on our software. A new generation of software libraries and lgorithms are needed for the effective and reliable use of (wide area) dynamic, distributed and parallel environments. Some of the software and algorithm challenges have already been encountered, such as management of communication and memory hierarchies through a combination of compile--time and run--time techniques, but the increased scale of computation, depth of memory hierarchies,more » range of latencies, and increased run--time environment variability will make these problems much harder. We will focus on the redesign of software to fit multicore architectures. Speaker: Jack Dongarra University of Tennessee Oak Ridge National Laboratory University of Manchester Jack Dongarra received a Bachelor of Science in Mathematics from Chicago State University in 1972 and a Master of Science in Computer Science from the Illinois Institute of Technology in 1973. He received his Ph.D. in Applied Mathematics from the University of New Mexico in 1980. He worked at the Argonne National Laboratory until 1989, becoming a senior scientist. He now holds an appointment as University Distinguished Professor of Computer Science in the Electrical Engineering and Computer Science Department at the University of Tennessee, has the position of a Distinguished Research Staff member in the Computer Science and Mathematics Division at Oak Ridge National Laboratory (ORNL), Turing Fellow in the Computer Science and Mathematics Schools at the University of Manchester, and an Adjunct Professor in the Computer Science Department at Rice University. He specializes in numerical algorithms in linear algebra, parallel computing, the use of advanced-computer architectures, programming methodology, and tools for parallel computers. His research includes the development, testing and documentation of high quality mathematical software. He has contributed to the design and implementation of the following open source software packages and systems: EISPACK, LINPACK, the BLAS, LAPACK, ScaLAPACK, Netlib, PVM, MPI, NetSolve, Top500, ATLAS, and PAPI. He has published approximately 200 articles, papers, reports and technical memoranda and he is coauthor of several books. He was awarded the IEEE Sid Fernbach Award in 2004 for his contributions in the application of high performance computers using innovative approaches. He is a Fellow of the AAAS, ACM, and the IEEE and a member of the National Academy of Engineering.« less

  17. 76 FR 54001 - Agency Information Collection (Election To Apply Selected Reserve Services to either Montgomery...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-30

    ... To Apply Selected Reserve Services to either Montgomery GI Bill-Active Duty or to the Montgomery GI... Selected Reserve Services to Either Montgomery GI Bill-Active Duty or to the Montgomery GI Bill-Selected.... Abstract: Reservist who participant in the Montgomery GI Bill-- Active Duty and served on active duty for...

  18. 10 CFR 431.444 - Test procedures for the measurement of energy efficiency.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the following test methods: (1) Single-phase small electric motors: either IEEE Std 114, (incorporated...) Polyphase small electric motors less than or equal to 1 horsepower (0.746 kW): IEEE Std 112 (incorporated by... (0.746 kW): IEEE Std 112 (incorporated by reference, see § 431.443), Test Method B. ...

  19. Study of Electromagnetic Wave Absorption Properties of Carbon Nanotubes-Based Composites

    DTIC Science & Technology

    2012-11-29

    Publications: [1]. G. L. Zhao, Z. Ye, Z. Li, J. A. Roberts, "New carbon nanotube-epoxy composite for dampening microwave cavity resonance", IEEE Xplore ...Nanotechnology ( IEEE - NANO), 2012 12th IEEE Conference on 20-23 Aug. 2012. [2]. Z. Li, G. L. Zhao, P. Zhang, S. Guo, J. Tang, " Thermoelectric

  20. Enabling interoperability in Geoscience with GI-suite

    NASA Astrophysics Data System (ADS)

    Boldrini, Enrico; Papeschi, Fabrizio; Santoro, Mattia; Nativi, Stefano

    2015-04-01

    GI-suite is a brokering framework targeting interoperability of heterogeneous systems in the Geoscience domain. The framework is composed by different brokers each one focusing on a specific functionality: discovery, access and semantics (i.e. GI-cat, GI-axe, GI-sem). The brokering takes place between a set of heterogeneous publishing services and a set of heterogeneous consumer applications: the brokering target is represented by resources (e.g. coverages, features, or metadata information) required to seamlessly flow from the providers to the consumers. Different international and community standards are now supported by GI-suite, making possible the successful deployment of GI-suite in many international projects and initiatives (such as GEOSS, NSF BCube and several EU funded projects). As for the publisher side more than 40 standards and implementations are supported (e.g. Dublin Core, OAI-PMH, OGC W*S, Geonetwork, THREDDS Data Server, Hyrax Server, etc.). The support for each individual standard is provided by means of specific GI-suite components, called accessors. As for the consumer applications side more than 15 standards and implementations are supported (e.g. ESRI ArcGIS, Openlayers, OGC W*S, OAI-PMH clients, etc.). The support for each individual standard is provided by means of specific profiler components. The GI-suite can be used in different scenarios by different actors: - A data provider having a pre-existent data repository can deploy and configure GI-suite to broker it and making thus available its data resources through different protocols to many different users (e.g. for data discovery and/or data access) - A data consumer can use GI-suite to discover and/or access resources from a variety of publishing services that are already publishing data according to well-known standards. - A community can deploy and configure GI-suite to build a community (or project-specific) broker: GI-suite can broker a set of community related repositories and make their content available (for discovery and/or access) through specific service interfaces. The GI-conf web tool can be used to easily configure GI-suite. By enabling specific accessors and profilers, as well as many other settings, GI-suite can be tailored to the desired use scenario. Moreover, thanks to its flexible architecture, GI-suite can be easily extended to support a new standard or implementation: a Java Development Kit is available to help development of new extensions (e.g. a new accessor component).

  1. Number and type of guideline implementation tools varies by guideline, clinical condition, country of origin, and type of developer organization: content analysis of guidelines.

    PubMed

    Liang, Laurel; Abi Safi, Jhoni; Gagliardi, Anna R

    2017-11-15

    Guideline implementation tools (GI tools) can improve clinician behavior and patient outcomes. Analyses of guidelines published before 2010 found that many did not offer GI tools. Since 2010 standards, frameworks and instructions for GI tools have emerged. This study analyzed the number and types of GI tools offered by guidelines published in 2010 or later. Content analysis and a published GI tool framework were used to categorize GI tools by condition, country, and type of organization. English-language guidelines on arthritis, asthma, colorectal cancer, depression, diabetes, heart failure, and stroke management were identified in the National Guideline Clearinghouse. Screening and data extraction were in triplicate. Findings were reported with summary statistics. Eighty-five (67.5%) of 126 eligible guidelines published between 2010 and 2017 offered one or more of a total of 464 GI tools. The mean number of GI tools per guideline was 5.5 (median 4.0, range 1 to 28) and increased over time. The majority of GI tools were for clinicians (239, 51.5%), few were for patients (113, 24.4%), and fewer still were to support implementation (66, 14.3%) or evaluation (46, 9.9%). Most clinician GI tools were guideline summaries (116, 48.5%), and most patient GI tools were condition-specific information (92, 81.4%). Government agencies (patient 23.5%, clinician 28.9%, implementation 24.1%, evaluation 23.5%) and developers in the UK (patient 18.5%, clinician 25.2%, implementation 27.2%, evaluation 29.1%) were more likely to generate guidelines that offered all four types of GI tools. Professional societies were more likely to generate guidelines that included clinician GI tools. Many guidelines do not include any GI tools, or a variety of GI tools for different stakeholders that may be more likely to prompt guideline uptake (point-of-care forms or checklists for clinicians, decision-making or self-management tools for patients, implementation and evaluation tools for managers and policy-makers). While this may vary by country and type of organization, and suggests that developers could improve the range of GI tools they develop, further research is needed to identify determinants and potential solutions. Research is also needed to examine the cost-effectiveness of various types of GI tools so that developers know where to direct their efforts and scarce resources.

  2. Upper GI Bleeding in Children

    MedlinePlus

    Upper GI Bleeding in Children What is upper GI Bleeding? Irritation and ulcers of the lining of the esophagus, stomach or duodenum can result in upper GI bleeding. When this occurs the child may vomit ...

  3. A comprehensive typology for mainstreaming urban green infrastructure

    NASA Astrophysics Data System (ADS)

    Young, Robert; Zanders, Julie; Lieberknecht, Katherine; Fassman-Beck, Elizabeth

    2014-11-01

    During a National Science Foundation (US) funded "International Greening of Cities Workshop" in Auckland, New Zealand, participants agreed an effective urban green infrastructure (GI) typology should identify cities' present stage of GI development and map next steps to mainstream GI as a component of urban infrastructure. Our review reveals current GI typologies do not systematically identify such opportunities. We address this knowledge gap by developing a new typology incorporating political, economic, and ecological forces shaping GI implementation. Applying this information allows symmetrical, place-based exploration of the social and ecological elements driving a city's GI systems. We use this information to distinguish current levels of GI development and clarify intervention opportunities to advance GI into the mainstream of metropolitan infrastructure. We employ three case studies (San Antonio, Texas; Auckland, New Zealand; and New York, New York) to test and refine our typology.

  4. Lower bound on the time complexity of local adiabatic evolution

    NASA Astrophysics Data System (ADS)

    Chen, Zhenghao; Koh, Pang Wei; Zhao, Yan

    2006-11-01

    The adiabatic theorem of quantum physics has been, in recent times, utilized in the design of local search quantum algorithms, and has been proven to be equivalent to standard quantum computation, that is, the use of unitary operators [D. Aharonov in Proceedings of the 45th Annual Symposium on the Foundations of Computer Science, 2004, Rome, Italy (IEEE Computer Society Press, New York, 2004), pp. 42-51]. Hence, the study of the time complexity of adiabatic evolution algorithms gives insight into the computational power of quantum algorithms. In this paper, we present two different approaches of evaluating the time complexity for local adiabatic evolution using time-independent parameters, thus providing effective tests (not requiring the evaluation of the entire time-dependent gap function) for the time complexity of newly developed algorithms. We further illustrate our tests by displaying results from the numerical simulation of some problems, viz. specially modified instances of the Hamming weight problem.

  5. Computer vision-based classification of hand grip variations in neurorehabilitation.

    PubMed

    Zariffa, José; Steeves, John D

    2011-01-01

    The complexity of hand function is such that most existing upper limb rehabilitation robotic devices use only simplified hand interfaces. This is in contrast to the importance of the hand in regaining function after neurological injury. Computer vision technology has been used to identify hand posture in the field of Human Computer Interaction, but this approach has not been translated to the rehabilitation context. We describe a computer vision-based classifier that can be used to discriminate rehabilitation-relevant hand postures, and could be integrated into a virtual reality-based upper limb rehabilitation system. The proposed system was tested on a set of video recordings from able-bodied individuals performing cylindrical grasps, lateral key grips, and tip-to-tip pinches. The overall classification success rate was 91.2%, and was above 98% for 6 out of the 10 subjects. © 2011 IEEE

  6. The GABAergic System and the Gastrointestinal Physiopathology.

    PubMed

    Auteri, Michelangelo; Zizzo, Maria Grazia; Serio, Rosa

    2015-01-01

    Since the first report about the presence of γ-aminobutyric acid (GABA) within the gastrointestinal (GI) tract, accumulating evidence strongly supports the widespread representation of the GABAergic system in the enteric milieu, underlining its potential multifunctional role in the regulation of GI functions in health and disease. GABA and GABA receptors are widely distributed throughout the GI tract, constituting a complex network likely regulating the diverse GI behaviour patterns, cooperating with other major neurotransmitters and mediators for maintaining GI homeostasis in physiologic and pathologic conditions. GABA is involved in the circuitry of the enteric nervous system, controlling GI secretion and motility, as well as in the GI endocrine system, possibly acting as a autocrine/paracrine or hormonal agent. Furthermore, a series of investigations addresses the GABAergic system as a potential powerful modulator of GI visceral pain processing, enteric immune system and carcinogenesis. Although overall such actions may imply the consideration of the GABAergic system as a novel therapeutic target in different GI pathologic states, including GI motor and secretory diseases and different enteric inflammatory- and pain-related pathologies, current clinical applications of GABAergic drugs are scarce. Thus, in an attempt to propel novel scientific efforts addressing the detailed characterization of the GABAergic signaling in the GI tract, and consequently the development of novel strategies for the treatment of different GI disorders, we reviewed and discussed the current evidence about GABA actions in the enteric environment, with a particular focus on their possible therapeutic implications.

  7. Study of Allocation Guaranteed Time Slot Wireless Body Area Networks Based on IEEE 802.15.4

    NASA Astrophysics Data System (ADS)

    Yundra, E.; Harsono, G. D.

    2018-04-01

    This paper aims to determine the size of the Guaranteed Time Slot (GTS) on the super frame structure required for each sensor as well as to know the performance of the GTS resized system compared to the GTS standard on IEEE 802.15.4. This article proposes a scheme to improve IEEE 802.15.4 medium access control, called allocation Guaranteed Time Slot (ALGATIS). ALGATIS is expected to effectively allocate guaranteed time slot to the requested sensors, it adjusts the length of the slot in super frame duration based on the length of the packet data. This article presents a simulation experiment of IEEE 802.15.4, especially for star network, to predict the throughput of networks and average energy consumption. The simulation experiments show that the performance of ALGATIS is better than that of IEEE 802.15.4 standard in term of the throughput of networks and average energy consumption

  8. Emergency pancreatoduodenectomy (whipple procedure) for massive upper gastrointestinal bleeding caused by a diffuse B-cell lymphoma of the duodenum: report of a case.

    PubMed

    Stratigos, Panagiotis; Kouskos, Efstratios; Kouroglou, Maria; Chrisafis, Ioannis; Fois, Lucia; Mavrogiorgis, Anastasios; Axiotis, Efthimios; Zamtrakis, Sotirios

    2007-01-01

    We herein report a rare case of a massive upper gastrointestinal (GI) bleeding, caused by high-grade diffuse B-cell lymphoma of the duodenum, secondary to immunoproliferative small intestinal disease (IPSID) and treated with an emergency partial pancreatoduodenectomy. A 42-year-old man was admitted to our hospital because of hematemesis. Upper GI endoscopy was unrevealing because of the copious bleeding. Initially, the patient underwent conservative treatment, thus resulting in the temporary cessation of the bleeding. Later, the hemorrhage massively relapsed. An urgent abdominal ultrasound raised the suspicion of a large, possibly bleeding, neoplasm of the duodenum, which was finally confirmed by abdominal computed tomography. The patient underwent an emergency laparotomy, during which a partial pancreatoduodenectomy was performed (Whipple procedure). Histologically, the tumor was a high-grade B-cell lymphoma of the duodenum. The nearby small intestinal mucosa was suggestive of IPSID. A massive upper GI hemorrhage from a high-grade B-cell non-Hodgkin lymphoma of the duodenum, which develops secondary to IPSID, is a very rare clinical demonstration of this disease. Our case is one of the few reports in the English literature, for which the Whipple procedure has been performed as a curative treatment.

  9. Burden of Acute Gastrointestinal Illness in Gálvez, Argentina, 2007

    PubMed Central

    Perez, Enrique; Majowicz, Shannon E.; Reid-Smith, Richard; Albil, Silvia; Monteverde, Marcos; McEwen, Scott A.

    2010-01-01

    This study evaluated the magnitude and distribution of acute gastrointestinal illness (GI) in Gálvez, Argentina, and assessed the outcome of a seven-day versus 30-day recall period in survey methodology. A cross-sectional population survey, with either a seven-day or a 30-day retrospective recall period, was conducted through door-to-door visits to randomly-selected residents during the ‘high’ and the ‘low’ seasons of GI in the community. Comparisons were made between the annual incidence rates obtained using the seven-day and the 30-day recall period. Using the 30-day recall period, the mean annual incidence rates was 0.43 (low season of GI) and 0.49 (high season of GI) episodes per person-year. Using the seven-day recall period, the mean annual incidence rate was 0.76 (low season of GI) and 2.66 (high season of GI) episodes per person-year. This study highlights the significant burden of GI in a South American community and confirms the importance of seasonality when investigating GI in the population. The findings suggest that a longer recall period may underestimate the burden of GI in retrospective population surveys of GI. PMID:20411678

  10. Low glycemic index breakfasts and reduced food intake in preadolescent children.

    PubMed

    Warren, Janet M; Henry, C Jeya K; Simonite, Vanessa

    2003-11-01

    Recent reports have suggested that a low glycemic index (GI) diet may have a role in the management of obesity through its ability to increase the satiety value of food and modulate appetite. To date, no long-term clinical trials have examined the effect of dietary GI on body weight regulation. The majority of evidence comes from single-day studies, most of which have been conducted in adults. The purpose of this study was to investigate the effect of 3 test breakfasts-low-GI, low-GI with 10% added sucrose, and high-GI-on ad libitum lunch intake, appetite, and satiety and to compare these with baseline values when habitual breakfast was consumed. A 3-way crossover study using block randomization of breakfast type was conducted in a school that already ran a breakfast club. A total of 37 children aged 9 to 12 years (15 boys and 22 girls) completed the study. The proportion of nonoverweight to overweight/obese children was 70:30. Children were divided into 5 groups, and a rolling program was devised whereby, week by week, each group would randomly receive 1 of 3 test breakfasts for 3 consecutive days, with a minimum of 5 weeks between the test breakfasts. Participants acted as their own control. The 3 test breakfasts were devised to match the energy and nutritional content of an individual's habitual breakfast as far as possible. All test breakfasts were composed of fruit juice, cereal, and milk with/without bread and margarine; foods with an appropriate GI value were selected. After each test breakfast, children were instructed not to eat or drink anything until lunchtime, except water and a small serving of fruit supplying approximately 10 g of carbohydrate, which was provided. Breakfast palatability, satiation after breakfast, and satiety before lunch were measured using rating scales based on previously used tools. Lunch was a buffet-style meal, and children were allowed free access to a range of foods. Lunch was served in the school hall where the rest of the schoolchildren were eating. Food intake at lunch was unobtrusively observed and recorded. Leftovers and food swapping were recorded, and plate waste was estimated. Lunch intakes were analyzed using a multilevel regression model for repeated measures data. The likelihood ratio statistic was used to determine whether the type of breakfast eaten had a significant effect on lunch intake after allowing for sex and weight status. The type of breakfast eaten had a statistically significant effect on mean energy intake at lunchtime: lunch intake was lower after low-GI and low-GI with added sucrose breakfasts compared with lunch intake after high-GI and habitual breakfasts (which were high-GI). Overweight and sex did not have a significant effect on lunch intake. Pairwise comparisons among the 3 types of test breakfasts and between each test breakfast and habitual breakfast were made. Lunch intake after the high-GI breakfast was significantly higher than after the low-GI breakfast and low-GI breakfast with added sucrose. The details of the pairwise comparisons were as follows: high-GI versus low-GI = 145 +/- 54 kcal; high-GI versus low-GI plus sucrose = 119 +/- 53 kcal; low-GI plus sucrose versus low-GI = 27 +/- 54 kcal. Lunch intake after the low-GI breakfast and the low-GI breakfast with added sucrose was significantly lower than after the habitual breakfast. The details of the pairwise comparisons were as follows: low-GI versus habitual = -109 +/- 75 kcal; low-GI plus sucrose versus habitual = -83 +/- 75 kcal; high-GI versus habitual = 36 +/- 75 kcal. There were no significant differences between the test breakfasts in immediate satiation. The high-GI breakfasts were rated to be more palatable than the low-GI breakfasts. At lunchtime, hunger ratings were greater after the high-GI breakfast compared with the other 2 test breakfasts on 2 of the 3 experimental days. Prelunch satiety scales were inversely related to subsequent food intake. These results suggest that low-GI foods eaten at breakfast have a significant impact on food intake at lunch. This is the first study to observe such an effect in a group of normal and overweight children and adds to the growing body of evidence that low-GI foods may have an important role in weight control and obesity management. The potentially confounding effect of differences in the macronutrient and dietary fiber content of the test breakfasts warrants additional study. In addition, the impact of GI on food intake and body weight regulation in the long term needs to be investigated.

  11. Evaluation of a telemetric gastrointestinal pill for continuous monitoring of gastrointestinal temperature in horses at rest and during exercise.

    PubMed

    Verdegaal, Elisabeth-Lidwien J M M; Delesalle, Catherine; Caraguel, Charles G B; Folwell, Louise E; McWhorter, Todd J; Howarth, Gordon S; Franklin, Samantha H

    2017-07-01

    OBJECTIVE To evaluate use of a telemetric gastrointestinal (GI) pill to continuously monitor GI temperature in horses at rest and during exercise and to compare time profiles of GI temperature and rectal temperature. ANIMALS 8 Standardbred horses. PROCEDURES Accuracy and precision of the GI pill and a rectal probe were determined in vitro by comparing temperature measurements with values obtained by a certified resistance temperature detector (RTD) in water baths at various temperatures (37°, 39°, and 41°C). Subsequently, both GI and rectal temperature were recorded in vivo in 8 horses over 3 consecutive days. The GI temperature was recorded continuously, and rectal temperature was recorded for 3.5 hours daily. Comparisons were made between GI temperature and rectal temperature for horses at rest, during exercise, and after exercise. RESULTS Water bath evaluation revealed good agreement between the rectal probe and RTD. However, the GI pill systematically underestimated temperature by 0.14°C. In vivo, GI temperature data were captured with minimal difficulties. Most data loss occurred during the first 16 hours, after which the mean ± SD data loss was 8.6 ± 3.7%. The GI temperature was consistently and significantly higher than rectal temperature with an overall mean temperature difference across time of 0.27°C (range, 0.22° to 0.32°C). Mean measurement cessation point for the GI pill was 5.1 ± 1.0 days after administration. CONCLUSIONS AND CLINICAL RELEVANCE This study revealed that the telemetric GI pill was a reliable and practical method for real-time monitoring of GI temperature in horses.

  12. Central Line-Associated Bloodstream Infections in Neonates with Gastrointestinal Conditions: developing a candidate definition for mucosal barrier injury bloodstream infections

    PubMed Central

    Coffin, Susan E.; Klieger, Sarah B.; Duggan, Christopher; Huskins, W. Charles; Milstone, Aaron M.; Potter-Bynoe, Gail; Raphael, Bram; Sandora, Thomas J.; Song, Xiaoyan; Zerr, Danielle M.; Lee, Grace M.

    2015-01-01

    Objectives To develop a candidate definition for central line-associated blood stream infection (CLABSI) in neonates with presumed mucosal barrier injury due to gastrointestinal (MBI-GI) conditions; to evaluate epidemiology and microbiology of MBI-GI CLABSI in infants. Design Multicenter retrospective cohort study Setting Neonatal intensive care units (NICU) from 14 U.S. children’s hospitals and pediatric facilities Methods A multidisciplinary focus group developed a candidate MBI-GI CLABSI definition based on presence of a MBI-GI condition, parenteral nutrition (PN) exposure, and an eligible enteric organism. CLABSI surveillance data from participating hospitals were supplemented by chart review to identify MBI-GI conditions and PN exposure. Results During 2009–12, 410 CLABSI occurred in 376 infants. MBI-GI conditions and PN exposure occurred in 149 (40%) and 324 (86%) of these 376 neonates, respectively. The distribution of pathogens was similar among neonates with versus without MBI-GI conditions and PN exposure. Fifty-nine (16%) of the 376 initial CLABSI episodes met the candidate MBI-GI CLABSI definition. Subsequent versus initial CLABSI were more likely to be caused by an enteric organism (22 of 34, 65% vs. 151 of 376, 40%; p = 0.009) and to meet the candidate MBI-GI CLABSI definition (19 of 34, 56% vs. 59 of 376, 16%; p < 0.01). Conclusions While MBI-GI conditions and PN exposure were common, only 16% of initial CLABSI met the candidate definition of MBI-GI CLABSI. The high proportion of MBI-GI CLABSI among subsequent infections suggests infants with MBI-GI CLABSI should be a population targeted for further surveillance and interventional research. PMID:25333434

  13. Marked Genomic Diversity of Norovirus Genogroup I Strains in a Waterborne Outbreak

    PubMed Central

    Hannoun, Charles; Larsson, Charlotte U.; Bergström, Tomas

    2012-01-01

    Marked norovirus (NoV) diversity was detected in patient samples from a large community outbreak of gastroenteritis with waterborne epidemiology affecting approximately 2,400 people. NoV was detected in 33 of 50 patient samples examined by group-specific real-time reverse transcription-PCR. NoV genotype I (GI) strains predominated in 31 patients, with mixed GI infections occurring in 5 of these patients. Sequence analysis of RNA-dependent polymerase-N/S capsid-coding regions (∼900 nucleotides in length) confirmed the dominance of the GI strains (n = 36). Strains of NoV GI.4 (n = 21) and GI.7 (n = 9) were identified, but six strains required full capsid amino acid analyses (530 to 550 amino acids) based on control sequencing of cloned amplicons before the virus genotype could be determined. Three strains were assigned to a new NoV GI genotype, proposed as GI.9, based on capsid amino acid analyses showing 26% dissimilarity from the established genotypes GI.1 to GI.8. Three other strains grouped in a sub-branch of GI.3 with 13 to 15% amino acid dissimilarity to GI.3 GenBank reference strains. Phylogenetic analysis (2.1 kb) of 10 representative strains confirmed these genotype clusters. Strains of NoV GII.4 (n = 1), NoV GII.6 (n = 2), sapovirus GII.2 (n = 1), rotavirus (n = 3), adenovirus (n = 1), and Campylobacter spp. (n = 2) were detected as single infections or as mixtures with NoV GI. Marked NoV GI diversity detected in patients was consistent with epidemiologic evidence of waterborne NoV infections, suggesting human fecal contamination of the water supply. Recognition of NoV diversity in a cluster of patients provided a useful warning marker of waterborne contamination in the Lilla Edet outbreak. PMID:22247153

  14. Further Results on the Disturbance Response of a Double Integrator Controlled by Saturating Linear Static State Feedback

    DTIC Science & Technology

    2011-07-13

    Anton A. Stoorvogel b, Håvard Fjær Grip a aSchool of Electrical Engineering and Computer Science, Washington State University, Pullman, WA 99164-2752...utwente.nl ( Anton A. Stoorvogel), grip@ieee.org (Håvard Fjær Grip). of a double integrator controlled by a saturating linear static state feedback...References Chitour, Y., 2001. On the Lp stabilization of the double integrator subject to input saturation. ESAIM: Control, Optimization and Calculus

  15. Generalizing the Nonlocal-Means to Super-Resolution Reconstruction

    DTIC Science & Technology

    2008-12-12

    Image Process., vol. 5, no. 6, pp. 996–1011, Jun. 1996. [7] A. J. Patti, M. I. Sezan, and M. A. Tekalp, “ Superresolution video reconstruction with...computationally efficient image superresolution algorithm,” IEEE Trans. Image Process., vol. 10, no. 4, pp. 573–583, Apr. 2001. [13] M. Elad and Y...pp. 21–36, May 2003. [18] S. Farsiu, D. Robinson, M. Elad, and P. Milanfar, “Robust shift and add approach to superresolution ,” in Proc. SPIE Conf

  16. Letters: Comment on "Effects of multi-scattering on the performance of a single-beam acoustic manipulation device".

    PubMed

    Mitri, F G

    2013-11-01

    The concern addressed in the present commentary is to point out the omission of the azimuthal component Fφ of the axial acoustic radiation force provided in M. Azarpeyvand, M. A. Alibakhshi, R. Self, "Effects of multi-scattering on the performance of a single-beam acoustic manipulation device," IEEE Trans. Ultrason. Ferroelectr. Freq. Control, vol. 59, no. 8, pp. 1741-1749, 2012, which may suggest a miscalculation of the radiation force function Ym and its related numerical computations.

  17. Proceedings of the NASTRAN (Tradename) Users’ Colloquium (14th) Held in San Diego, California on 5-9 May 1986

    DTIC Science & Technology

    1986-05-01

    4. Bossi, J. A., Price, G. A., and Winkleblack, S. A., " Flexible Spacecraft Controller Design Using the Integrated Analysis Capability (IAC)," AIAA...P., "Integrated Control System Design Capabilities at the Goddard Space Flight Center," Pro- ceedings of the 2nd IEEE Control Systems Society...Symposium on Computer- Aided Control System Design (CACSD), Santa Barbara, California, March, 13-15 1985. 6. Frisch, H. P. "Integrated Analysis Capability

  18. Radio Wave Propagation: A Handbook of Practical Techniques for Computing Basic Transmission Loss and Field Strength

    DTIC Science & Technology

    1982-09-01

    MARK A. WEISSBEGU KALLE R. XONTSON Project Msnaqer, IUTRZ Assistant Director Contractor Operations Approved by CRARLES L. FLYNN, 001, us A. M. MESSE...34 BSTJ, 1946. 2-4priis, H.T., "Introduction to Radio and Antennas," IEEE Spectrum, April, 1971 . RADIO WAVE PROPAGATION: A HANDBOOK OF PRACTICAL...Propagation Tests, TR-0177-71.01, Gautney & Jones Communications, Inc., Falls Church, VA, June 1971 . 3 -7 Comparison of Predicted VLF/LF Signal

  19. A Man-Portable Vector Sensor for Identification of Unexploded Ordnance

    DTIC Science & Technology

    2011-08-24

    Hanover data of Section III-B2, and Dr. L. Pasion , J. Jacobson, and H. Ngo of Sky Research and Dr. L.-P. Song of the University of British Columbia for...of equivalent dipole polarizabilities in situ,” IEEE Trans. Geosci. Remote Sens., vol. 43, no. 7, pp. 1490–1498, Jul. 2005. [27] L. R. Pasion and D. W...P. Song, F. Shubitidze, L. R. Pasion , D. W. Oldenburg, and S. D. Billings, “Computing transient electromagnetic responses of a metallic object using

  20. A Framework for Managing the Assured Information Sharing Lifecycle

    DTIC Science & Technology

    2013-11-06

    Mohamed Nabeel , Elisa Bertino: Privacy preserving delegated access control in the storage as a service model. IRI 2012: 645-652 • Mohamed Nabeel , Ning...2012: 67-68 • M. Nabeel , J. Zage, S. Kerr, E. Bertino, N. Athula Kulatunga, U. Sudheera Navaratne, M. Duren: Crypto- graphic Key Management for Smart...Military Communications Conf., Nov.2011. • Pramod Jagtap, Anupam Joshi, Tim Finin and Laura Zavala, Preserving Privacy in Context-Aware Sys - tems, Proc. 5th IEEE Int. Conf. on Semantic Computing, Oct. 2011.

  1. IEEE Computer Society/Software Engineering Institute Watts S. Humphrey Software Process Achievement Award 2016: Raytheon Integrated Defense Systems Design for Six Sigma Team

    DTIC Science & Technology

    2017-04-01

    notice for non -US Government use and distribution. External use: This material may be reproduced in its entirety, without modification, and freely...Combinatorial Design Methods 4 2.1 Identification of Significant Improvement Opportunity 4 2.2 Methodology Development 4 2.3 Piloting...11 3 Process Performance Modeling and Analysis 13 3.1 Identification of Significant Improvement Opportunity 13 3.2 Methodology Development 13 3.3

  2. Image Understanding Workshop. Proceedings of a Workshop Held in Los Angeles, California on 23-25 February 1987. Volume 2

    DTIC Science & Technology

    1987-02-25

    Modellierung von Kanten bei unregel. Navigation within a building, to be published in IEEE mifliger Rasterung in Bildverarbeitun uand Muster...converted them into equivalent machine cycles in Table 3-1. We took into account of 100 nanosecond 0 - 0, machine cycle time of the MPP. In MPP, NON- VON ...We show the result for the conjugate gradient method in of NON- VON . We assumed that the instructions which carry Table 4-4. The computation of four

  3. Clustering Similarity Digest Bloom Filters in Self-Organizing Maps

    DTIC Science & Technology

    2012-12-01

    www.sciencedirect.com/science/article/ pii/S1742287610000368 [4] M. Rogers, J . Goldman, R. Mislan, T. Wedge, and S. Debrota, “Computer forensics field triage...1990. [9] T. Kohonen, S. Kaski, K. Lagus, J . Salojarvi, J . Honkela, V. Paatero, and A. Saarela, “Self organization of a massive document collection...the IEEE-INNS-ENNS Interna- tional Joint Conference on, vol. 6, 2000, pp. 15 –19 vol.6. [12] G. Salton , A. Wong, and C. Yang, “A vector space model for

  4. Understanding the Structure of Large, Diverse Collections of Shapes

    DTIC Science & Technology

    2013-06-01

    lowest weight edges as candidates, and for each candidate, we compute its edge rank, which is a metric proposed by Heath et al. [51] that estimates the... Neil D. McKay. A method for registration of 3-d shapes. IEEE PAMI, 14(2):239–256, February 1992. [10] V. Blanz, K. Scherbaum, and H.-P. Seidel. Fitting...2011. [50] C. Gu and X. Ren. Discriminative mixture-of-templates for viewpoint classification. In ECCV, 2010. [51] K. Heath , N. Gelfand, M

  5. Proceedings of the Intelligent Tutoring Systems Research Forum (2nd) Held in San Antonio, Texas on 6-7 April 1989

    DTIC Science & Technology

    1990-04-01

    REFERENCES Carbonell, J.R. (1970). A] in CAI: An artifcial intelligence approach to computer-assisted instruction. IEEE Transactions on Man-Machine Systems...of intelligent systems use outcome data of any sort (Anderson, in press, is an exception). Other designers describe system goals for learners and then...5601 90 o9 3007 NOTICE When Government drawings, specifications, or other data are used for any purpose other than in connection with a definitely

  6. Quantum State Tomography of a Fiber-Based Source of Polarization-Entangled Photon Pairs

    DTIC Science & Technology

    2007-12-20

    Processing 175−179 (IEEE, Bangalore, 1984). 4. A. K. Ekert, “ Quantum cryptography based on Bell’s theorem ,” Phys. Rev. Lett. 67, 661–663 (1991). 5...NUMBERS Quantum State Tomography of a Fiber- Based Source of MURI Center for Photonic Quantum Information Systems: AROIARDA Program Polarization...Computer Society Press, Los Alamitos, 1996). 7. N. Gisin, G. Ribordy, W. Tittel, and H. Zbinden, “ Quantum cryptography ,” Rev. Mod. Phys. 74, 145

  7. 75 FR 21664 - Underwriters Laboratories Inc.; Application for Expansion of Recognition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... in Metal-Enclosed Switchgear \\a\\ IEEE C37.20.6 4.76 kV to 38 kV Rated Grounding and Testing Devices Used in Enclosures \\a\\ IEEE C37.23 Metal-Enclosed Bus \\a\\ IEEE C37.41 High-Voltage Fuses, Distribution... Electrical Equipment UL 852 Metallic Sprinkler Pipe for Fire Protection Service UL 962 Household and...

  8. Dark Energy Survey Year 1 Results: Cross-Correlation Redshifts in the DES -- Calibration of the Weak Lensing Source Redshift Distributions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Davis, C.; et al.

    We present the calibration of the Dark Energy Survey Year 1 (DES Y1) weak lensing source galaxy redshift distributions from clustering measurements. By cross-correlating the positions of source galaxies with luminous red galaxies selected by the redMaGiC algorithm we measure the redshift distributions of the source galaxies as placed into different tomographic bins. These measurements constrain any such shifts to an accuracy ofmore » $$\\sim0.02$$ and can be computed even when the clustering measurements do not span the full redshift range. The highest-redshift source bin is not constrained by the clustering measurements because of the minimal redshift overlap with the redMaGiC galaxies. We compare our constraints with those obtained from $$\\texttt{COSMOS}$$ 30-band photometry and find that our two very different methods produce consistent constraints.« less

  9. Extraskeletal osteosarcoma, telangiectatic variant arising from the small bowel mesentery.

    PubMed

    Hussain, Muhammad I; Al-Akeely, Mohammed H; Alam, Mohammed K; Jasser, Nayel A

    2011-09-01

    Extraskeletal osteosarcoma (EOS) is a highly aggressive and rare malignant soft tissue tumor, characterized by the production of neoplastic osseous tissue without attachment to the bone or periosteum. It rarely involves the visceral organs. Only 3 cases of mesenteric EOS have been reported in English literature. Here, we describe a male patient of 40 years, who was diagnosed to have EOS arising from small bowel mesentery. This patient presented with lower gastrointestinal (GI) bleeding. Upper GI endoscopy and colonoscopy were normal. Computed tomography scan demonstrated a well defined multi-loculated mixed density mass lesion measuring about 13x7x7 cm in lower abdomen adjacent to small bowel loops with liver metastasis. Palliative en bloc resection of tumor with adjacent small bowel was performed. The histopathology revealed a telangiectatic type osteosarcoma of mesentery. Diagnosis of EOS, its management and the outcome in context of the current literature are discussed.

  10. Gastrointestinal Bleeding in Patients With Atrial Fibrillation Treated With Rivaroxaban or Warfarin: ROCKET AF Trial.

    PubMed

    Sherwood, Matthew W; Nessel, Christopher C; Hellkamp, Anne S; Mahaffey, Kenneth W; Piccini, Jonathan P; Suh, Eun-Young; Becker, Richard C; Singer, Daniel E; Halperin, Jonathan L; Hankey, Graeme J; Berkowitz, Scott D; Fox, Keith A A; Patel, Manesh R

    2015-12-01

    Gastrointestinal (GI) bleeding is a common complication of oral anticoagulation. This study evaluated GI bleeding in patients who received at least 1 dose of the study drug in the on-treatment arm of the ROCKET AF (Rivaroxaban Once-daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation) trial. The primary outcome was adjudicated GI bleeding reported from first to last drug dose + 2 days. Multivariable modeling was performed with pre-specified candidate predictors. Of 14,236 patients, 684 experienced GI bleeding during follow-up. These patients were older (median age 75 years vs. 73 years) and less often female. GI bleeding events occurred in the upper GI tract (48%), lower GI tract (23%), and rectum (29%) without differences between treatment arms. There was a significantly higher rate of major or nonmajor clinical GI bleeding in rivaroxaban- versus warfarin-treated patients (3.61 events/100 patient-years vs. 2.60 events/100 patient-years; hazard ratio: 1.42; 95% confidence interval: 1.22 to 1.66). Severe GI bleeding rates were similar between treatment arms (0.47 events/100 patient-years vs. 0.41 events/100 patient-years; p = 0.39; 0.01 events/100 patient-years vs. 0.04 events/100 patient-years; p = 0.15, respectively), and fatal GI bleeding events were rare (0.01 events/100 patient-years vs. 0.04 events/100 patient-years; 1 fatal events vs. 5 fatal events total). Independent clinical factors most strongly associated with GI bleeding were baseline anemia, history of GI bleeding, and long-term aspirin use. In the ROCKET AF trial, rivaroxaban increased GI bleeding compared with warfarin. The absolute fatality rate from GI bleeding was low and similar in both treatment arms. Our results further illustrate the need for minimizing modifiable risk factors for GI bleeding in patients on oral anticoagulation. Copyright © 2015 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  11. Synthesis and Anticancer Activity of 2-(Alkyl-, Alkaryl-, Aryl-, Hetaryl-)-[1,2,4]triazolo[1,5-c]quinazolines

    PubMed Central

    Kovalenko, Sergiy I.; Antypenko, Lyudmyla M.; Bilyi, Andriy K.; Kholodnyak, Sergiy V.; Karpenko, Olexandr V.; Antypenko, Olexii M.; Mykhaylova, Natalya S.; Los, Tetyana I.; Kolomoets, Olexandra S.

    2013-01-01

    The combinatorial library of novel potential anticancer agents, namely, 2-(alkyl-, alkaryl-, aryl-, hetaryl-)[1,2,4]triazolo[1,5-c]quinazolines, was synthesized by the heterocyclization of the alkyl-, alkaryl-, aryl-, hetarylcarboxylic acid (3H-quinazoline-4-ylidene)hydrazides by oxidative heterocyclization of the 4-(arylidenehydrazino)quinazolines using bromine, and by the heterocyclization of N-(2-cyanophenyl)formimidic acid ethyl ester. The optimal method for synthesis of the s-triazolo[1,5-c]quinazolines appeared to be cyclocondensation of the corresponding carboxylic acid (3H-quinazoline-4-ylidene)hydrazides. The compounds’ structures were established by 1H, 13C NMR, LC- and EI-MS analysis. The in vitro screening of anticancer activity determined the most active compound to be 3,4,5-trimethoxy-N′-[quinazolin-4(3H)-ylidene]benzohydrazide (3.20) in micromolar concentrations with the GI50 level (MG_MID, GI50 is 2.29). Thus, the cancer cell lines whose growth is greatly inhibited by compound 3.20 are: non-small cell lung cancer (NCI-H522, GI50=0.34), CNS (SF-295, GI50=0.95), ovarian (OVCAR-3, GI50=0.33), prostate (PC-3, GI50=0.56), and breast cancer (MCF7, GI50=0.52), leukemia (K-562, GI50=0.41; SR, GI50=0.29), and melanoma (MDA-MB-435, GI50=0.31; SK-MEL-5, GI50=0.74; UACC-62, GI50=0.32). SAR-analysis is also discussed. PMID:23833709

  12. Gastrointestinal bleeding with dabigatran, a comparative study with warfarin: a multicenter experience.

    PubMed

    Sherid, Muhammed; Sifuentes, Humberto; Sulaiman, Samian; Samo, Salih; Husein, Husein; Tupper, Ruth; Spurr, Charles; Sridhar, Subbaramiah

    2015-04-01

    The risk of gastrointestinal (GI) bleeding with dabigatran when compared to warfarin has been controversial in the literature. The aim of our study was to assess this risk with the use of dabigatran. We examined the medical records of patients who were started on dabigatran or warfarin from October 2010 to October 2012. The study was conducted in two hospitals. A total of 417 patients were included (208 dabigatran vs. 209 warfarin). GI bleeding occurred in 10 patients (4.8%) in the dabigatran group compared to 21 patients (10.1%) in the warfarin group (p=0.0375). Multivariate analysis showed that patients who were on dabigatran for ≤ 100 days had a higher incidence of GI bleeding than those who were on it for >100 days (p=0.0007). The odds of GI bleeding in patients who were on dabigatran for ≤ 100 days was 8.2 times higher compared to those who were on the drug for >100 days. The incidence of GI bleeding in patients >65 years old was higher than in those <65 years old (p=0.0453, OR=3). History of previous GI bleeding was another risk factor for GI bleeding in the dabigatran group (p=0.036, OR=6.3). The lower GI tract was the most common site for GI bleeding in the dabigatran group (80.0% vs. 38.1%, p=0.014). The risk of GI bleeding was lower with dabigatran. The risk factors for GI bleeding with dabigatran were the first 100 days, age >65 years, and a history of previous GI bleeding.

  13. GI-conf: A configuration tool for the GI-cat distributed catalog

    NASA Astrophysics Data System (ADS)

    Papeschi, F.; Boldrini, E.; Bigagli, L.; Mazzetti, P.

    2009-04-01

    In this work we present a configuration tool for the GI-cat. In an Service-Oriented Architecture (SOA) framework, GI-cat implements a distributed catalog service providing advanced capabilities, such as: caching, brokering and mediation functionalities. GI-cat applies a distributed approach, being able to distribute queries to the remote service providers of interest in an asynchronous style, and notifies the status of the queries to the caller implementing an incremental feedback mechanism. Today, GI-cat functionalities are made available through two standard catalog interfaces: the OGC CSW ISO and CSW Core Application Profiles. However, two other interfaces are under testing: the CIM and the EO Extension Packages of the CSW ebRIM Application Profile. GI-cat is able to interface a multiplicity of discovery and access services serving heterogeneous Earth and Space Sciences resources. They include international standards like the OGC Web Services -i.e. OGC CSW, WCS, WFS and WMS, as well as interoperability arrangements (i.e. community standards) such as: UNIDATA THREDDS/OPeNDAP, SeaDataNet CDI (Common Data Index), GBIF (Global Biodiversity Information Facility) services, and SibESS-C infrastructure services. GI-conf implements user-friendly configuration tool for GI-cat. This is a GUI application that employs a visual and very simple approach to configure both the GI-cat publishing and distribution capabilities, in a dynamic way. The tool allows to set one or more GI-cat configurations. Each configuration consists of: a) the catalog standards interfaces published by GI-cat; b) the resources (i.e. services/servers) to be accessed and mediated -i.e. federated. Simple icons are used for interfaces and resources, implementing a user-friendly visual approach. The main GI-conf functionalities are: • Interfaces and federated resources management: user can set which interfaces must be published; besides, she/he can add a new resource, update or remove an already federated resource. • Multiple configuration management: multiple GI-cat configurations can be defined; every configuration identifies a set of published interfaces and a set of federated resources. Configurations can be edited, added, removed, exported, and even imported. • HTML report creation: an HTML report can be created, showing the current active GI-cat configuration, including the resources that are being federated and the published interface endpoints. The configuration tool is shipped with GI-cat and can be used to configure the service after its installation is completed.

  14. A spatially augmented reality sketching interface for architectural daylighting design.

    PubMed

    Sheng, Yu; Yapo, Theodore C; Young, Christopher; Cutler, Barbara

    2011-01-01

    We present an application of interactive global illumination and spatially augmented reality to architectural daylight modeling that allows designers to explore alternative designs and new technologies for improving the sustainability of their buildings. Images of a model in the real world, captured by a camera above the scene, are processed to construct a virtual 3D model. To achieve interactive rendering rates, we use a hybrid rendering technique, leveraging radiosity to simulate the interreflectance between diffuse patches and shadow volumes to generate per-pixel direct illumination. The rendered images are then projected on the real model by four calibrated projectors to help users study the daylighting illumination. The virtual heliodon is a physical design environment in which multiple designers, a designer and a client, or a teacher and students can gather to experience animated visualizations of the natural illumination within a proposed design by controlling the time of day, season, and climate. Furthermore, participants may interactively redesign the geometry and materials of the space by manipulating physical design elements and see the updated lighting simulation. © 2011 IEEE Published by the IEEE Computer Society

  15. Biomedical learning experiences for middle school girls sponsored by the Kansas State University Student Chapter of the IEEE EMBS.

    PubMed

    Gruber, Lucinda; Griffith, Connor; Young, Ethan; Sullivan, Adriann; Schuler, Jeff; Arnold-Christian, Susan; Warren, Steve

    2009-01-01

    Learning experiences for middle school girls are an effective means to steer young women toward secondary engineering curricula that they might not have otherwise considered. Sponsorship of such experiences by a collegiate student group is worthwhile, as it gives the group common purpose and places college students in a position to mentor these young women. This paper addresses learning experiences in different areas of bio-medical engineering offered to middle school girls in November 2008 via a day-long workshop entitled "Engineering The Body." The Kansas State University (KSU) Student Chapter of the IEEE Engineering in Medicine and Biology Society (EMBS) worked with the KSU Women in Engineering and Science Program (WESP) to design and sponsor these experiences, which addressed the areas of joint mechanics, electrocardiograms, membrane transport, computer mouse design, and audio filters for cochlear implants. Fifty five middle-school girls participated in this event, affirming the notion that biomedical engineering appeals to young women and that early education and recruitment efforts have the potential to expand the biomedical engineering talent pool.

  16. Numerical assessment of the performance of a scalp-implantable antenna: effects of head anatomy and dielectric parameters.

    PubMed

    Kiourti, Asimina; Nikita, Konstantina S

    2013-04-01

    We numerically assess the effects of head properties (anatomy and dielectric parameters) on the performance of a scalp-implantable antenna for telemetry in the Medical Implant Communications Service band (402.0-405.0 MHz). Safety issues and performance (resonance, radiation) are analyzed for an experimentally validated implantable antenna (volume of 203.6 mm(3) ), considering five head models (3- and 5-layer spherical, 6-, 10-, and 13-tissue anatomical) and seven scenarios (variations ± 20% in the reference permittivity and conductivity values). Simulations are carried out at 403.5 MHz using the finite-difference time-domain method. Anatomy of the head model around the implantation site is found to mainly affect antenna performance, whereas overall tissue anatomy and dielectric parameters are less significant. Compared to the reference dielectric parameter scenario within the 3-layer spherical head, maximum variations of -19.9%, +3.7%, -55.1%, and -39.2% are computed in the maximum allowable net input power imposed by the IEEE Std C95.1-1999 and Std C95.1-2005 safety guidelines, return loss, and maximum far-field gain, respectively. Compliance with the recent IEEE Std C95.1-2005 is found to be almost insensitive to head properties, in contrast with IEEE Std C95.1-1999. Taking tissue property uncertainties into account is highlighted as crucial for implantable antenna design and performance assessment. Bioelectromagnetics 34:167-179, 2013. © 2012 Wiley Periodicals, Inc. Copyright © 2012 Wiley Periodicals, Inc.

  17. Computational Analysis of the CB1 Carboxyl-terminus in the Receptor-G Protein Complex

    PubMed Central

    Shim, Joong-Youn; Khurana, Leepakshi; Kendall, Debra A.

    2016-01-01

    Despite the important role of the carboxyl-terminus (Ct) of the activated brain cannabinoid receptor one (CB1) in the regulation of G protein signaling, a structural understanding of interactions with G proteins is lacking. This is largely due to the highly flexible nature of the CB1 Ct that dynamically adapts its conformation to the presence of G proteins. In the present study, we explored how the CB1 Ct can interact with the G protein by building on our prior modeling of the CB1-Gi complex (Shim J-Y, Ahn KH, Kendall DA. The Journal of Biological Chemistry 2013;288:32449-32465) to incorporate a complete CB1 Ct (Glu416Ct–Leu472Ct). Based upon the structural constraints from NMR studies, we employed ROSETTA to predict tertiary folds, ZDOCK to predict docking orientation, and molecular dynamics (MD) simulations to obtain two distinct plausible models of CB1 Ct in the CB1-Gi complex. The resulting models were consistent with the NMR-determined helical structure (H9) in the middle region of the CB1 Ct. The CB1 Ct directly interacted with both Gα and Gβ and stabilized the receptor at the Gi interface. The results of site-directed mutagenesis studies of Glu416Ct, Asp423Ct, Asp428Ct, and Arg444Ct of CB1 Ct suggested that the CB1 Ct can influence receptor-G protein coupling by stabilizing the receptor at the Gi interface. This research provided, for the first time, models of the CB1 Ct in contact with the G protein. PMID:26994549

  18. Diagnostic value of alarm symptoms for upper GI malignancy in patients referred to GI clinic: A 7 years cross sectional study.

    PubMed

    Emami, Mohammad Hasan; Ataie-Khorasgani, Masoud; Jafari-Pozve, Nasim

    2017-01-01

    Early upper gastrointestinal (UGI) cancer detection had led to organ-preserving endoscopic therapy. Endoscopy is a suitable method of early diagnosis of UGI malignancies. In Iran, exclusion of malignancy is the most important indication for endoscopy. This study is designed to see whether using alarm symptoms can predict the risk of cancer in patients. A total of 3414 patients referred to a tertiary gastrointestinal (GI) clinic in Isfahan, Iran, from 2009 to 2016 with dyspepsia, gastroesophageal reflux disease (GERD), and alarm symptoms, such as weight loss, dysphagia, GI bleeding, vomiting, positive familial history for cancer, and anorexia. Each patient had been underwent UGI endoscopy and patient data, including histology results, had been collected in the computer. We used logistic regression models to estimate the diagnostic accuracy of each alarm symptoms. A total of 3414 patients with alarm symptoms entered in this study, of whom 72 (2.1%) had an UGI malignancy. According to the logistic regression model, dysphagia ( P < 0.001) and weight loss ( P < 0.001) were found to be significant positive predictive factors for malignancy. Furthermore, males were in a significantly higher risk of developing UGI malignancy. Through receiver operating characteristic curve and the area under the curve (AUC) with adequate overall calibration and model fit measures, dysphagia and weight loss as a related cancer predictor had a high diagnostic accuracy (accuracy = 0. 72, AUC = 0. 881). Using a combination of age, alarm symptoms will lead to high positive predictive value for cancer. We recommend to do an early endoscopy for any patient with UGI symptoms and to take multiple biopsies from any rudeness or suspicious lesion, especially for male gender older than 50, dysphagia, or weight loss.

  19. A flexible framework for process-based hydraulic and water ...

    EPA Pesticide Factsheets

    Background Models that allow for design considerations of green infrastructure (GI) practices to control stormwater runoff and associated contaminants have received considerable attention in recent years. While popular, generally, the GI models are relatively simplistic. However, GI model predictions are being relied upon by many municipalities and State/Local agencies to make decisions about grey vs. green infrastructure improvement planning. Adding complexity to GI modeling frameworks may preclude their use in simpler urban planning situations. Therefore, the goal here was to develop a sophisticated, yet flexible tool that could be used by design engineers and researchers to capture and explore the effect of design factors and properties of the media used in the performance of GI systems at a relatively small scale. We deemed it essential to have a flexible GI modeling tool that is capable of simulating GI system components and specific biophysical processes affecting contaminants such as reactions, and particle-associated transport accurately while maintaining a high degree of flexibly to account for the myriad of GI alternatives. The mathematical framework for a stand-alone GI performance assessment tool has been developed and will be demonstrated.Framework Features The process-based model framework developed here can be used to model a diverse range of GI practices such as green roof, retention pond, bioretention, infiltration trench, permeable pavement and

  20. Structural analysis of determinants of histo-blood group antigen binding specificity in genogroup I noroviruses.

    PubMed

    Shanker, Sreejesh; Czako, Rita; Sankaran, Banumathi; Atmar, Robert L; Estes, Mary K; Prasad, B V Venkataram

    2014-06-01

    Human noroviruses (NoVs) cause acute epidemic gastroenteritis. Susceptibility to the majority of NoV infections is determined by genetically controlled secretor-dependent expression of histo-blood group antigens (HBGAs), which are also critical for NoV attachment to host cells. Human NoVs are classified into two major genogroups (genogroup I [GI] and GII), with each genogroup further divided into several genotypes. GII NoVs are more prevalent and exhibit periodic emergence of new variants, suggested to be driven by altered HBGA binding specificities and antigenic drift. Recent epidemiological studies show increased activity among GI NoVs, with some members showing the ability to bind nonsecretor HBGAs. NoVs bind HBGAs through the protruding (P) domain of the major capsid protein VP1. GI NoVs, similar to GII, exhibit significant sequence variations in the P domain; it is unclear how these variations affect HBGA binding specificities. To understand the determinants of possible strain-specific HBGA binding among GI NoVs, we determined the structure of the P domain of a GI.7 clinical isolate and compared it to the previously determined P domain structures of GI.1 and GI.2 strains. Our crystallographic studies revealed significant structural differences, particularly in the loop regions of the GI.7 P domain, altering its surface topography and electrostatic landscape and potentially indicating antigenic variation. The GI.7 strain bound to H- and A-type, Lewis secretor, and Lewis nonsecretor families of HBGAs, allowing us to further elucidate the structural determinants of nonsecretor HBGA binding among GI NoVs and to infer several contrasting and generalizable features of HBGA binding in the GI NoVs. Human noroviruses (NoVs) cause acute epidemic gastroenteritis. Recent epidemiological studies have shown increased prevalence of genogroup I (GI) NoVs. Although secretor-positive status is strongly correlated with NoV infection, cases of NoV infection associated with secretor-negative individuals are reported. Biochemical studies have shown that GI NoVs exhibit genotype-dependent binding to nonsecretor histo-blood group antigens (HBGAs). From our crystallographic studies of a GI.7 NoV, in comparison with previous studies on GI.1 and GI.2 NoVs, we show that genotypic differences translate to extensive structural changes in the loop regions that significantly alter the surface topography and electrostatic landscape of the P domain; these features may be indicative of antigenic variations contributing to serotypic differentiation in GI NoVs and also differential modulation of the HBGA binding characteristics. A significant finding is that the threshold length and the structure of one of the loops are critical determinants in the binding of GI NoVs to nonsecretor HBGAs.

  1. 10 CFR 431.444 - Test procedures for the measurement of energy efficiency.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... the following test methods: (1) Single-phase small electric motors: Either IEEE Std 114-2010 or CSA... to 1 horsepower (0.75 kW): Either IEEE Std 112-2004 Test Method A or CSA C747 (incorporated by...): Either IEEE Std 112-2004 Test Method B or CSA C390-10 (incorporated by reference, see § 431.443). [74 FR...

  2. 10 CFR 431.444 - Test procedures for the measurement of energy efficiency.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... the following test methods: (1) Single-phase small electric motors: Either IEEE Std 114-2010 or CSA... to 1 horsepower (0.75 kW): Either IEEE Std 112-2004 Test Method A or CSA C747 (incorporated by...): Either IEEE Std 112-2004 Test Method B or CSA C390-10 (incorporated by reference, see § 431.443). [74 FR...

  3. Virtualization of AEGIS: A Study of the Feasibility of Applying Open Architecture Technology to the Surface Navy’s Most Complex Automated Weapon System

    DTIC Science & Technology

    2011-09-01

    diagnostics system. Aerospace and Electronic Systems Magazine, IEEE , 9(2), 40–45. Current version released August 2002 in IEEE Xplore . doi: 10.1109...Cramming more components onto integrated circuits. Electronics, 114–117. Reprinted January 1998 in Proceedings of the IEEE , 86(1), 82–85. doi: S 0018

  4. ARO PECASE: Information Assurance for Energy-Constrained Wireless Sensor Networks

    DTIC Science & Technology

    2011-12-21

    Distribution, 18th Annual IEEE International Symposium on Personal, Indoor, and Mobile Radio Communications (PIMRC), September 2007. 2. 2010 IEEE...received the following awards: Student Best Paper Award at the IEEE International Symposium on Personal, Indoor, and Mobile Radio Communications (PIMRC...Localization in Wireless Ad Hoc Networks – Many current and future appli- cations of mobile ad hoc networks, including disaster response and event

  5. GIGANTEA directly activates Flowering Locus T in Arabidopsis thaliana.

    PubMed

    Sawa, Mariko; Kay, Steve A

    2011-07-12

    Plants perceive environmental signals such as day length and temperature to determine optimal timing for the transition from vegetative to floral stages. Arabidopsis flowers under long-day conditions through the CONSTANS (CO)-FLOWERING LOCUS T (FT) regulatory module. It is thought that the environmental cues for photoperiodic control of flowering are initially perceived in the leaves. We have previously shown that GIGANTEA (GI) regulates the timing of CO expression, together with FLAVIN-BINDING, KELCH REPEAT, F BOX protein 1. Normally, CO and FT are expressed exclusively in vascular bundles, whereas GI is expressed in various tissues. To better elucidate the role of tissue-specific expression of GI in the flowering pathway, we established transgenic lines in which GI is expressed exclusively in mesophyll, vascular bundles, epidermis, shoot apical meristem, or root. We found that GI expressed in either mesophyll or vascular bundles rescues the late-flowering phenotype of the gi-2 loss-of-function mutant under both short-day and long-day conditions. Interestingly, GI expressed in mesophyll or vascular tissues increases FT expression without up-regulating CO expression under short-day conditions. Furthermore, we examined the interaction between GI and FT repressors in mesophyll. We found that GI can bind to three FT repressors: SHORT VEGETATIVE PHASE (SVP), TEMPRANILLO (TEM)1, and TEM2. Finally, our chromatin immunoprecipitation experiments showed that GI binds to FT promoter regions that are near the SVP binding sites. Taken together, our data further elucidate the multiple roles of GI in the regulation of flowering time.

  6. Selection of Brain Metastasis-Initiating Breast Cancer Cells Determined by Growth on Hard Agar

    PubMed Central

    Guo, Lixia; Fan, Dominic; Zhang, Fahao; Price, Janet E.; Lee, Ju-Seog; Marchetti, Dario; Fidler, Isaiah J.; Langley, Robert R.

    2011-01-01

    An approach that facilitates rapid isolation and characterization of tumor cells with enhanced metastatic potential is highly desirable. Here, we demonstrate that plating GI-101A human breast cancer cells on hard (0.9%) agar selects for the subpopulation of metastasis-initiating cells. The agar-selected cells, designated GI-AGR, were homogeneous for CD44+ and CD133+ and five times more invasive than the parental GI-101A cells. Moreover, mice injected with GI-AGR cells had significantly more experimental brain metastases and shorter overall survival than did mice injected with GI-101A cells. Comparative gene expression analysis revealed that GI-AGR cells were markedly distinct from the parental cells but shared an overlapping pattern of gene expression with the GI-101A subline GI-BRN, which was generated by repeated in vivo recycling of GI-101A cells in an experimental brain metastasis model. Data mining on 216 genes shared between GI-AGR and GI-BRN breast cancer cells suggested that the molecular phenotype of these cells is consistent with that of cancer stem cells and the aggressive basal subtype of breast cancer. Collectively, these results demonstrate that analysis of cell growth in a hard agar assay is a powerful tool for selecting metastasis-initiating cells in a heterogeneous population of breast cancer cells, and that such selected cells have properties similar to those of tumor cells that are selected based on their potential to form metastases in mice. PMID:21514446

  7. Flexible Description and Adaptive Processing of Earth Observation Data through the BigEarth Platform

    NASA Astrophysics Data System (ADS)

    Gorgan, Dorian; Bacu, Victor; Stefanut, Teodor; Nandra, Cosmin; Mihon, Danut

    2016-04-01

    The Earth Observation data repositories extending periodically by several terabytes become a critical issue for organizations. The management of the storage capacity of such big datasets, accessing policy, data protection, searching, and complex processing require high costs that impose efficient solutions to balance the cost and value of data. Data can create value only when it is used, and the data protection has to be oriented toward allowing innovation that sometimes depends on creative people, which achieve unexpected valuable results through a flexible and adaptive manner. The users need to describe and experiment themselves different complex algorithms through analytics in order to valorize data. The analytics uses descriptive and predictive models to gain valuable knowledge and information from data analysis. Possible solutions for advanced processing of big Earth Observation data are given by the HPC platforms such as cloud. With platforms becoming more complex and heterogeneous, the developing of applications is even harder and the efficient mapping of these applications to a suitable and optimum platform, working on huge distributed data repositories, is challenging and complex as well, even by using specialized software services. From the user point of view, an optimum environment gives acceptable execution times, offers a high level of usability by hiding the complexity of computing infrastructure, and supports an open accessibility and control to application entities and functionality. The BigEarth platform [1] supports the entire flow of flexible description of processing by basic operators and adaptive execution over cloud infrastructure [2]. The basic modules of the pipeline such as the KEOPS [3] set of basic operators, the WorDeL language [4], the Planner for sequential and parallel processing, and the Executor through virtual machines, are detailed as the main components of the BigEarth platform [5]. The presentation exemplifies the development of some Earth Observation oriented applications based on flexible description of processing, and adaptive and portable execution over Cloud infrastructure. Main references for further information: [1] BigEarth project, http://cgis.utcluj.ro/projects/bigearth [2] Gorgan, D., "Flexible and Adaptive Processing of Earth Observation Data over High Performance Computation Architectures", International Conference and Exhibition Satellite 2015, August 17-19, Houston, Texas, USA. [3] Mihon, D., Bacu, V., Colceriu, V., Gorgan, D., "Modeling of Earth Observation Use Cases through the KEOPS System", Proceedings of the Intelligent Computer Communication and Processing (ICCP), IEEE-Press, pp. 455-460, (2015). [4] Nandra, C., Gorgan, D., "Workflow Description Language for Defining Big Earth Data Processing Tasks", Proceedings of the Intelligent Computer Communication and Processing (ICCP), IEEE-Press, pp. 461-468, (2015). [5] Bacu, V., Stefan, T., Gorgan, D., "Adaptive Processing of Earth Observation Data on Cloud Infrastructures Based on Workflow Description", Proceedings of the Intelligent Computer Communication and Processing (ICCP), IEEE-Press, pp.444-454, (2015).

  8. Optional Sub-study to Intraoperative Imaging With ICG Registry

    ClinicalTrials.gov

    2016-07-19

    Lung, Prostate, Breast, Colon, Pancreatic, Renal, Bladder,Thyroid, Ovarian, Head and Neck,GI (Foregut - Esophagus),GI (Midgut) Cancer; Cancer of the Ovarian, Head and Neck,GI (Foregut - Esophagus),GI (Midgut), Sarcoma Cancer; Cancer of Neuro-onc, Parathyroid, Desmoid Tumors, Melanoma Cancer

  9. A prospective evaluation of undiagnosed joint hypermobility syndrome in patients with gastrointestinal symptoms.

    PubMed

    Fikree, Asma; Grahame, Rodney; Aktar, Rubina; Farmer, Adam D; Hakim, Alan J; Morris, Joan K; Knowles, Charles H; Aziz, Qasim

    2014-10-01

    The Joint Hypermobility Syndrome (JHS) is a common connective tissue disorder characterized by joint hyperflexibility, dysautonomia, and chronic pain. Gastrointestinal (GI) symptoms are reported in JHS patients attending rheumatology clinics, but the prevalence and symptom pattern of previously undiagnosed JHS in GI clinics are unknown. By using validated questionnaires, a prospective cross-sectional study in secondary care GI clinics estimated the prevalence of JHS in new consecutively referred patients, compared GI symptoms in patients with and without JHS, and by using multiple regression determined whether the burden of GI symptoms in JHS patients was dependent on chronic pain, autonomic, psychological, and medication related factors. A positive control group consisted of JHS patients referred from rheumatology clinics with GI symptoms (JHS-Rh). From 552 patients recruited, 180 (33%) had JHS (JHS-G) and 372 did not (non-JHS-G). Forty-four JHS-Rh patients were included. JHS-G patients were more likely to be younger, female with poorer quality of life (P = .02) than non-JHS-G patients. After age and sex matching, heartburn (odds ratio [OR], 1.66; confidence interval [CI], 1.1-2.5; P = .01), water brash (OR, 2.02; CI, 1.3-3.1; P = .001), and postprandial fullness (OR, 1.74; CI, 1.2-2.6; P = .006) were more common in JHS-G vs non-JHS-G. Many upper and lower GI symptoms increased with increasing severity of JHS phenotype. Upper GI symptoms were dependent on autonomic and chronic pain factors. JHS is common in GI clinics, with increased burden of upper GI and extraintestinal symptoms and poorer quality of life. Recognition of JHS will facilitate multidisciplinary management of GI and extra-GI manifestations. Copyright © 2014 AGA Institute. Published by Elsevier Inc. All rights reserved.

  10. Contributors to dietary glycaemic index and glycaemic load in the Netherlands: the role of beer.

    PubMed

    Sluik, Diewertje; Atkinson, Fiona S; Brand-Miller, Jennie C; Fogelholm, Mikael; Raben, Anne; Feskens, Edith J M

    2016-04-14

    Diets high in glycaemic index (GI) and glycaemic load (GL) have been associated with a higher diabetes risk. Beer explained a large proportion of variation in GI in a Finnish and an American study. However, few beers have been tested according to International Organization for Standardization (ISO) methodology. We tested the GI of beer and estimated its contribution to dietary GI and GL in the Netherlands. GI testing of pilsner beer (Pilsner Urquell) was conducted at The University of Sydney according to ISO international standards with glucose as the reference food. Subsequently, GI and GL values were assigned to 2556 food items in the 2011 Dutch food composition table using a six-step methodology and consulting four databases. This table was linked to dietary data from 2106 adults in the Dutch National Food Consumption Survey 2007-2010. Stepwise linear regression identified contribution to inter-individual variation in dietary GI and GL. The GI of pilsner beer was 89 (SD 5). Beer consumption contributed to 9·6 and 5·3% inter-individual variation in GI and GL, respectively. Other foods that contributed to the inter-individual variation in GI and GL included potatoes, bread, soft drinks, sugar, candy, wine, coffee and tea. The results were more pronounced in men than in women. In conclusion, beer is a high-GI food. Despite its relatively low carbohydrate content (approximately 4-5 g/100 ml), it still made a contribution to dietary GL, especially in men. Next to potatoes, bread, sugar and sugar-sweetened beverages, beer captured a considerable proportion of between-person variability in GI and GL in the Dutch diet.

  11. Effect of Gastrointestinal Malformations on the Outcomes of Patients With Congenital Heart Disease.

    PubMed

    Mery, Carlos M; De León, Luis E; Rodriguez, J Rubén; Nieto, R Michael; Zhang, Wei; Adachi, Iki; Heinle, Jeffrey S; Kane, Lauren C; McKenzie, E Dean; Fraser, Charles D

    2017-11-01

    The goal of this study was to assess the effect of associated gastrointestinal malformations (GI) on the outcomes of patients undergoing congenital heart operations. Neonates and infants with thoracic (esophageal atresia, tracheoesophageal fistula) and abdominal (duodenal stenosis/atresia, imperforate anus, Hirschsprung disease) GI malformations undergoing congenital heart operations between 1995 and 2015 were included. Two control groups were created, one for each group. Patients were matched by diagnosis, procedure, history of prematurity, presence of genetic syndrome, and a propensity score including weight and year of operation. The cohort included 383 patients: 52 (14%) with thoracic GI malformations and 98 (25%) thoracic GI controls, 80 (21%) with abdominal GI malformations and 153 (40%) abdominal GI controls. Median follow-up was 6 years (range, 16 days to 20 years). Patients with thoracic GI malformations had longer length of stay (p < 0.001), longer intubation times (p = 0.002), and higher perioperative death (p = 0.015) than controls. There was a tendency for worse overall survival than controls, mainly explained by the higher risk of early death (p = 0.06). No difference was found in outcomes between patients with abdominal GI malformations and controls. Patients with thoracic GI malformations have worse perioperative outcomes than controls, but their long-term survival does not seem to be significantly different. Abdominal GI malformations do not have a significant effect on outcomes. The presence of GI malformations should likely not preclude patients from undergoing congenital heart operations, but careful family counseling is necessary, especially for thoracic GI malformations. Copyright © 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  12. Effects of Lowering Glycemic Index of Dietary Carbohydrate on Plasma Uric Acid: The OmniCarb Randomized Clinical Trial

    PubMed Central

    Juraschek, Stephen P; McAdams-Demarco, Mara; Gelber, Allan C; Sacks, Frank M.; Appel, Lawrence J; White, Karen; Miller, Edgar R

    2017-01-01

    Objective The effects of carbohydrates on plasma uric acid levels are controversial. We determined the individual and combined effects of carbohydrate quality (glycemic index, GI) and quantity (proportion of total daily energy, %carb) on uric acid. Methods We conducted a randomized, crossover feeding trial in overweight or obese adults without cardiovascular disease (N=163). Participants were fed each of four diets over 5-week periods separated by 2-week washout periods. Body weight was kept constant. The four diets were: high GI (GI ≥65) with high %carb (58% kcal), low GI (GI ≤45) with low %carb (40% kcal), low GI with high %carb; and high GI with low %carb. Plasma uric acid was measured at baseline and after each feeding period for comparison between the 4 diets. Results Study participants were 52% women and 50% non-Hispanic black with a mean age of 52.6 years and a mean uric acid of 4.7 (SD, 1.2) mg/dL. Reducing GI lowered uric acid when the %carb was low (−0.24 mg/dL; P <0.001) or high (−0.17 mg/dL; P <0.001). Reducing the %carb marginally increased uric acid only when GI was high (P = 0.05). The combined effect of lowering GI and increasing the %carb was −0.27 mg/dL (P <0.001). This effect was observed even after adjustment for concurrent changes in kidney function, insulin sensitivity, and products of glycolysis. Conclusions Reducing GI lowers uric acid. Future studies should examine whether reducing GI can prevent gout onset or flares. TRIAL REGISTRATION clinicaltrials.gov, Identifier: NCT00608049 PMID:26636424

  13. "Data Acquisition Systems"

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Unterweger, Michael; Costrell, Louis deceased

    2009-07-07

    This project involved support for Lou Costrell and myself in the development of IEEE and IEC standards for nuclear counting and data acquisition systems. Over the years, as a result of this support, Lou and I were able to attend standards meetings of IEEE and IEC, which led directly to the publication of many standards for NIM systems, FastBus and CAMAC. We also chaired several writing committees as well as ANSI N42 (Nuclear instrumentation), IEEE NIM (NIM standard), IEEE NID (NPSS nuclear instruments and detector) and IEC TC45 WG9 (Nuclear instrumentation). Through this support we were able to assure thatmore » the interests of the US and DOE were expressed and implemented in the various standards.« less

  14. Gastrointestinal events in at-risk patients starting non-steroidal anti-inflammatory drugs (NSAIDs) for rheumatic diseases: the EVIDENCE study of European routine practice.

    PubMed

    Lanas, Angel; Boers, Maarten; Nuevo, Javier

    2015-04-01

    Data concerning rates of gastrointestinal (GI) events in non-steroidal anti-inflammatory drug (NSAID) users derive mainly from clinical trials. The EVIDENCE study quantified the incidence of symptomatic uncomplicated and/or complicated GI events in at-risk European patients treated with NSAIDs in real-life practice. This non-interventional study assessed 4144 adults with at least one GI risk factor who recently initiated NSAID therapy for osteoarthritis (85%), rheumatoid arthritis (11%), ankylosing spondylitis (3%) or a combination (1%). Patient characteristics and medical history were collected from medical records. GI events (upper and lower) were recorded at in-clinic visits during 6 months' follow-up. Mean time on index NSAID at enrolment was 33 days. The incidence (per 100 person-years) was 18.5 per 100 person-years for uncomplicated GI events and 0.7 per 100 person-years for complicated GI events. Upper GI events were far more common (12%) than lower GI events (1%) during study follow-up (median 182 days (range 61-320)). Other reported rates for cardiovascular, anaemia or non-GI events were much less frequent. A minority (28%) of patients had ongoing proton pump inhibitor use at enrolment, with strong variation by practice and country. EVIDENCE is the largest prospective study of the real-life management of European patients treated with NSAIDs for rheumatic diseases and at increased GI risk. It shows that GI events from the upper GI tract are far more common than those from the lower GI tract. It also shows adherence to guidelines for gastroprotection is generally low. NCT01176682. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  15. Microleakage in different primary tooth restorations.

    PubMed

    Shih, Wen-Yu

    2016-04-01

    Microleakage may cause tooth sensitivity, secondary caries, discoloration and even failure of the restoration. In order to overcome these potential problems, materials that are able to bind to the tooth structure have been developed, such as composite resin and glass ionomer cement. The purpose of the study was to compare microleakage arising from amalgam (Am), composite resin (CR), glass ionomer (GI), Ketac-Silver (KS), and GI filling with banding (GI+B) when these materials are used for class II restoration of a primary molar. Fifty primary molars were collected and class II cavities were prepared on each tooth. The teeth were randomly divided into five groups (Am, CR, GI, KS, and GI+B), each of which received a different material as part of the restoration. The restored teeth then underwent 100 cycles of thermocycling that consisted of 55°C for 30 seconds, 19°C for 20 seconds, and 5°C for 30 seconds. The teeth were then immersed in 0.5% basic fuchsin solution for 24 hours. Afterwards, the teeth were embedded and sectioned mesiodistally through the center of each restoration. Dye penetration associated with the occlusal and cervical margins of each restoration was then assessed. Cervical leakage was greater than occlusal leakage in the CR, GI and KS groups (p < 0.05). When leakage on occlusal margin was examined, however, the Am group showed greater leakage than the CR, GI, and GI+B groups (p < 0.05). When leakage on the cervical margin was examined, the Am group showed greater leakage than the GI and GI+B groups, while the KS group showed greater leakage than the GI+B group (p < 0.05). Restorations using GI and GI+B indicated that these materials performed better than the other materials in this study overall. However, none of the materials were entirely devoid of leakage. Copyright © 2016. Published by Elsevier Taiwan LLC.

  16. Investigating β-adrenergic-induced cardiac hypertrophy through computational approach: classical and non-classical pathways.

    PubMed

    Khalilimeybodi, Ali; Daneshmehr, Alireza; Sharif-Kashani, Babak

    2018-07-01

    The chronic stimulation of β-adrenergic receptors plays a crucial role in cardiac hypertrophy and its progression to heart failure. In β-adrenergic signaling, in addition to the well-established classical pathway, Gs/AC/cAMP/PKA, activation of non-classical pathways such as Gi/PI3K/Akt/GSK3β and Gi/Ras/Raf/MEK/ERK contribute in cardiac hypertrophy. The signaling network of β-adrenergic-induced hypertrophy is very complex and not fully understood. So, we use a computational approach to investigate the dynamic response and contribution of β-adrenergic mediators in cardiac hypertrophy. The proposed computational model provides insights into the effects of β-adrenergic classical and non-classical pathways on the activity of hypertrophic transcription factors CREB and GATA4. The results illustrate that the model captures the dynamics of the main signaling mediators and reproduces the experimental observations well. The results also show that despite the low portion of β2 receptors out of total cardiac β-adrenergic receptors, their contribution in the activation of hypertrophic mediators and regulation of β-adrenergic-induced hypertrophy is noticeable and variations in β1/β2 receptors ratio greatly affect the ISO-induced hypertrophic response. The model results illustrate that GSK3β deactivation after β-adrenergic receptor stimulation has a major influence on CREB and GATA4 activation and consequent cardiac hypertrophy. Also, it is found through sensitivity analysis that PKB (Akt) activation has both pro-hypertrophic and anti-hypertrophic effects in β-adrenergic signaling.

  17. Gastrointestinal dysfunction in idiopathic Parkinsonism: A narrative review

    PubMed Central

    Salari, Mehri; Fayyazi, Emad; Mirmosayyeb, Omid

    2016-01-01

    Currently, gastrointestinal (GI) dysfunctions in Parkinson's disease (PD) are well-recognized problems and are known to be the initial symptoms in the pathological process that eventually results in PD. Many types of PD-associated GI dysfunctions have been identified, including weight loss, nausea, hypersalivation, dysphagia, dyspepsia, abdominal pain, intestinal pseudo-obstruction, constipation, defecatory dysfunction, and small intestinal bacterial overgrowth. These symptoms can influence on other PD symptoms and are the second most significant predictor of the quality of life of these patients. Recognition of GI symptoms requires vigilance on the part of clinicians. Health-care providers should routinely ask direct questions about GI symptoms during office visits so that efforts can be directed at appropriate management of these distressing manifestations. Multiple system atrophy (MSA) and progressive supranuclear palsy are two forms of neurodegenerative Parkinsonism. Symptoms of autonomic dysfunctions such as GI dysfunction are common in patients with parkinsonian disorders. Despite recent progress in the recognition of GI dysfunctions, there are a few reviews on the management of GI dysfunction and GI symptoms in idiopathic Parkinsonism. In this review, the clinical presentation, pathophysiology, and treatment of each GI symptom in PD, MSA, and prostate-specific antigen will be discussed. PMID:28331512

  18. Risk Management Considerations for Interoperable Acquisition

    DTIC Science & Technology

    2006-08-01

    Electronics Engineers (IEEE) to harmonize the standards for software (IEEE 12207 ) and system (IEEE 15288) life-cycle processes. A goal of this harmonization...management ( ISO /IEC 16085) is being generalized to apply to the systems level. The revised, generalized standard will add require- ments and guidance for the...risk management. The documents include the following: • ISO /IEC Guide 73: Risk Management—Vocabulary—Guidelines for use in stan- dards [ ISO 02

  19. Should Security Researchers Experiment More and Draw More Inferences?

    DTIC Science & Technology

    2011-08-01

    knowledge would be enormous. To obtain a large and representative sample of keystroke-dynamics research papers, we consulted the IEEE Xplore database... IEEE Xplore are similar to those published elsewhere), these confidence intervals estimate the re- gions where those true percentages would lie with 95...of articles and conference pro- ceedings published by the IEEE , to which our university maintains a subscription. We conducted two keyword searches for

  20. Simulation Comparisons of Three Different Meander Line Dipoles

    DTIC Science & Technology

    2015-01-01

    Paez C I. Design formulas for a meandered dipole. IEEE Xplore Digital Library, 2014: n. pag. Web. 2 September 2014. 2. Nguyen, VH, Phan, HP, Hoang...MH. Improving radiation characteristics of UHF RFID antennas by zigzag structures. IEEE Xplore Digital Library, 2014: n. pag. Web. 2 September 2014...geometry-based, frequency-independent lumped element model. IEEE Xplore Digital Library, 2014: n. pag. Web. 2 September 2014. 5. Olaode OO, Palmer WD

  1. High Throughput via Cross-Layer Interference Alignment for Mobile Ad Hoc Networks

    DTIC Science & Technology

    2013-08-26

    MIMO zero-forcing receiver in the presence of channel estimation error,” IEEE Transactions on Wireless Communications , vol. 6 , no. 3, pp. 805–810, Mar...Robert W. Heath, Nachiappan Valliappan. Antenna Subset Modulation for Secure Millimeter-Wave Wireless Communication , IEEE Transactions on...in MIMO Interference Alignment Networks, IEEE Transactions on Wireless Communications , (02 2012): 0. doi: 10.1109/TWC.2011.120511.111088 TOTAL: 2

  2. Calendar of Selected Aeronautical and Space Meetings (Calendrier des Manifestations Aeronautiques et Spatiales (Selection)).

    DTIC Science & Technology

    1983-01-01

    Physique de l’Atmosphire et Environnement terrestre 71 09 - Information, Documentation et Informatique 74 10 - Thimes gin~raux (pluridisciplinaires) et...March Louisiana (US) Fiber Communication Optical Communications IEEE Fibre Optics Electro-Optics 02-08 7-9 March Baden-Baden VDE -IEEE Specialists...Conference on Very Large Electronic Systems VDE (GE) Scale Integrated Circuits Solid State Devices IEEE Integrated Circuits Engineering Design Fabrication

  3. IEEE 1547 and 2030 Standards for Distributed Energy Resources Interconnection and Interoperability with the Electricity Grid

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Basso, T.

    Public-private partnerships have been a mainstay of the U.S. Department of Energy and the National Renewable Energy Laboratory (DOE/NREL) approach to research and development. These partnerships also include technology development that enables grid modernization and distributed energy resources (DER) advancement, especially renewable energy systems integration with the grid. Through DOE/NREL and industry support of Institute of Electrical and Electronics Engineers (IEEE) standards development, the IEEE 1547 series of standards has helped shape the way utilities and other businesses have worked together to realize increasing amounts of DER interconnected with the distribution grid. And more recently, the IEEE 2030 series ofmore » standards is helping to further realize greater implementation of communications and information technologies that provide interoperability solutions for enhanced integration of DER and loads with the grid. For these standards development partnerships, for approximately $1 of federal funding, industry partnering has contributed $5. In this report, the status update is presented for the American National Standards IEEE 1547 and IEEE 2030 series of standards. A short synopsis of the history of the 1547 standards is first presented, then the current status and future direction of the ongoing standards development activities are discussed.« less

  4. Low glycaemic index diet and disposition index in type 2 diabetes (the Canadian trial of carbohydrates in diabetes): a randomised controlled trial.

    PubMed

    Wolever, T M S; Mehling, C; Chiasson, J-L; Josse, R G; Leiter, L A; Maheux, P; Rabasa-Lhoret, R; Rodger, N W; Ryan, E A

    2008-09-01

    We recently found that oral glucose tolerance over 1 year in type 2 diabetic patients declined to a significantly lesser degree on a low-glycaemic-index than on a reduced-carbohydrate diet. Here, we examined whether that finding was associated with an improvement in disposition index, an index of beta cell function defined as the product of insulin sensitivity and insulin secretion. Since this is a report of secondary analysis on a previously published trial, the results should be considered as hypothesis-generating. Type 2 diabetic patients treated by diet alone (n = 162) were randomised by computer to high-carbohydrate/high-glycaemic index (High-GI, n = 52), high-carbohydrate/low-glycaemic index (Low-GI, n = 56) or low-carbohydrate/high-monounsaturated-fat (Low-CHO, n = 54) diets for 1 year in a multi-centre, parallel-design clinical trial conducted at University teaching hospitals. At baseline and at 3, 6 and 12 months participants underwent 75 g OGTTs; 27 participants dropped out or were excluded. Indices of insulin sensitivity, insulin secretion and disposition index, derived from the OGTT, were compared among diets. Those assessing the outcomes were blinded to group assignment. Neither muscle insulin sensitivity index nor insulinogenic index differed significantly among diets. However, a significant time x diet interaction existed for disposition index (muscle insulin sensitivity index x insulinogenic index) (p = 0.036). After 3 months, disposition index tended to be higher on Low-CHO than on Low-GI diets, namely by 0.07 h(-1) (95% CI -0.04, 0.18). However, by 12 months this reversed and disposition index became higher on Low-GI than on Low-CHO, namely by 0.12 h(-1) (0.01, 0.23; p < 0.05, baseline disposition index 0.23 h(-1)). There were no important adverse effects associated with the treatments. These results suggest that, in patients with type 2 diabetes on diet alone, a Low-GI diet for 1 year increases disposition index, an index of beta cell function, compared with a Low-CHO diet.

  5. Galilean-invariant preconditioned central-moment lattice Boltzmann method without cubic velocity errors for efficient steady flow simulations

    NASA Astrophysics Data System (ADS)

    Hajabdollahi, Farzaneh; Premnath, Kannan N.

    2018-05-01

    Lattice Boltzmann (LB) models used for the computation of fluid flows represented by the Navier-Stokes (NS) equations on standard lattices can lead to non-Galilean-invariant (GI) viscous stress involving cubic velocity errors. This arises from the dependence of their third-order diagonal moments on the first-order moments for standard lattices, and strategies have recently been introduced to restore Galilean invariance without such errors using a modified collision operator involving corrections to either the relaxation times or the moment equilibria. Convergence acceleration in the simulation of steady flows can be achieved by solving the preconditioned NS equations, which contain a preconditioning parameter that can be used to tune the effective sound speed, and thereby alleviating the numerical stiffness. In the present paper, we present a GI formulation of the preconditioned cascaded central-moment LB method used to solve the preconditioned NS equations, which is free of cubic velocity errors on a standard lattice, for steady flows. A Chapman-Enskog analysis reveals the structure of the spurious non-GI defect terms and it is demonstrated that the anisotropy of the resulting viscous stress is dependent on the preconditioning parameter, in addition to the fluid velocity. It is shown that partial correction to eliminate the cubic velocity defects is achieved by scaling the cubic velocity terms in the off-diagonal third-order moment equilibria with the square of the preconditioning parameter. Furthermore, we develop additional corrections based on the extended moment equilibria involving gradient terms with coefficients dependent locally on the fluid velocity and the preconditioning parameter. Such parameter dependent corrections eliminate the remaining truncation errors arising from the degeneracy of the diagonal third-order moments and fully restore Galilean invariance without cubic defects for the preconditioned LB scheme on a standard lattice. Several conclusions are drawn from the analysis of the structure of the non-GI errors and the associated corrections, with particular emphasis on their dependence on the preconditioning parameter. The GI preconditioned central-moment LB method is validated for a number of complex flow benchmark problems and its effectiveness to achieve convergence acceleration and improvement in accuracy is demonstrated.

  6. Gastrointestinal Fistulas in Acute Pancreatitis With Infected Pancreatic or Peripancreatic Necrosis

    PubMed Central

    Jiang, Wei; Tong, Zhihui; Yang, Dongliang; Ke, Lu; Shen, Xiao; Zhou, Jing; Li, Gang; Li, Weiqin; Li, Jieshou

    2016-01-01

    Abstract Gastrointestinal (GI) fistula is a well-recognized complication of acute pancreatitis (AP). However, it has been reported in limited literature. This study aimed to evaluate the incidence and outcome of GI fistulas in AP patients complicated with infected pancreatic or peripancreatic necrosis (IPN). Between 2010 and 2013 AP patients with IPN who diagnosed with GI fistula in our center were analyzed in this retrospective study. And we also conducted a comparison between patients with and without GI fistula regarding the baseline characteristics and outcomes. Over 4 years, a total of 928 AP patients were admitted into our center, of whom 119 patients with IPN were diagnosed with GI fistula and they developed 160 GI fistulas in total. Colonic fistula found in 72 patients was the most common form of GI fistula followed with duodenal fistula. All duodenal fistulas were managed by nonsurgical management. Ileostomy or colostomy was performed for 44 (61.1%) of 72 colonic fistulas. Twenty-one (29.2%) colonic fistulas were successfully treated by percutaneous drainage or continuous negative pressure irrigation. Mortality of patients with GI fistula did not differ significantly from those without GI fistula (28.6% vs 21.9%, P = 0.22). However, a significantly higher mortality (34.7%) was observed in those with colonic fistula. GI fistula is a common finding in patients of AP with IPN. Most of these fistulas can be successfully managed with different procedures depending on their sites of origin. Colonic fistula is related with higher mortality than those without GI fistula. PMID:27057908

  7. Dietary hyperglycemia, glycemic index and age-related metabolic retinal diseases

    USDA-ARS?s Scientific Manuscript database

    The glycemic index (GI) indicates how fast blood glucose is raised after consuming a carbohydrate-containing food. Human metabolic studies indicate that GI is related to patho-physiological responses after meals. Compared with a low-GI meal, a high-GI meal is characterized with hyperglycemia during ...

  8. Glycemic index of cereals and tubers produced in China

    PubMed Central

    Yang, Yue-Xin; Wang, Hong-Wei; Cui, Hong-Mei; Wang, Yan; Yu, Lian-Da; Xiang, Shi-Xue; Zhou, Shui-Ying

    2006-01-01

    AIM: To determine the GI of some cereals and tubers produced in China in an effort to establish the database of glycemic index (GI) of Chinese food. METHODS: Food containing 50 g carbohydrate was consumed by 8-12 healthy adults after they have been fasted for 10 h and blood glucose was monitored for 2 h. Glucose was used as reference food. GI of food was calculated according to a standard method. RESULTS: GI of 9 types of sugar and 60 kinds of food were determined. CONCLUSION: Food GI is mainly determined by nature of carbohydrate and procession. Most of cereals and tubers produced in China have similar GI with their counterparts produced in other countries. PMID:16733864

  9. 75 FR 77002 - Expansion of the Scope of NRTL Recognition of Underwriters Laboratories Inc.; Modification to the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-10

    ...): IEEE C37.20.4 Indoor AC Switches (1 kV-38 kV) for Use in Metal-Enclosed Switchgear \\a\\ IEEE C37.20.6 4.76 kV to 38 kV Rated Grounding and Testing Devices Used in Enclosures \\a\\ IEEE C37.23 Metal-Enclosed... Sprinkler Pipe for Fire Protection Service UL 962 Household and Commercial Furnishings \\c\\ UL 1340 Hoists UL...

  10. Final Scientific Report,

    DTIC Science & Technology

    1980-11-26

    and J.B. Thomas, "The Effect of a Memoryless Nonlinearity on the Spectrum of a Random Process," IEEE Transactions on Information Theory, Vol. IT-23, pp...Density Function from Measurements Corrupted by Poisson Noise," IEEE Transactions on Information Theory, Vol. IT-23, pp. 764-766, November 1977. H. Derin...pp. 243-249, December 1977. G.L. Wise and N.C. Gallagher, "On Spherically Invariant Random Processes," IEEE Transactions on Information Theory, Vol. IT

  11. Throughput and delay analysis of IEEE 802.15.6-based CSMA/CA protocol.

    PubMed

    Ullah, Sana; Chen, Min; Kwak, Kyung Sup

    2012-12-01

    The IEEE 802.15.6 is a new communication standard on Wireless Body Area Network (WBAN) that focuses on a variety of medical, Consumer Electronics (CE) and entertainment applications. In this paper, the throughput and delay performance of the IEEE 802.15.6 is presented. Numerical formulas are derived to determine the maximum throughput and minimum delay limits of the IEEE 802.15.6 for an ideal channel with no transmission errors. These limits are derived for different frequency bands and data rates. Our analysis is validated by extensive simulations using a custom C+ + simulator. Based on analytical and simulation results, useful conclusions are derived for network provisioning and packet size optimization for different applications.

  12. IMACS 󈨟: Proceedings of the IMACS World Congress on Computation and Applied Mathematics (13th) Held in Dublin, Ireland on July 22-26, 1991. Volume 4. Modelling and Simulation for Electrical, Electronic and Semiconductor Devices, Computation for Management Systems, Applications of Modelling and Simulation, Environmental Systems Simulation, Software Forum, Poster Sessions

    DTIC Science & Technology

    1991-07-01

    synchronous machine case study . IEEE T rons. on For the ease nd -nq -2, four time scales trust be used And the A.C, Vol. 36. nul 3, March 1989. damnper... studied . A spot welded(Csse 3) * ss s i* r 0. or a line welded( Case 4) reinforcement plate is attached on the colliding surface of box beams arnd their...phased armature, is given on Figure 1. analytical field calculation in the machine magnetic structure. Il - MAGNETIC STRUCTURE MODELLING: In the case

  13. Glycemic index of American-grown jasmine rice classified as high.

    PubMed

    Truong, Teresa H; Yuet, Wei Cheng; Hall, Micki D

    2014-06-01

    The primary objective was to determine the glycemic index (GI) of jasmine rice grown in the United States (US). Secondary objective was to compare the GI of US grown jasmine rice to those grown in Thailand. Twelve healthy subjects were served all four brands of jasmine rice and a reference food (glucose), each containing 50 g of available carbohydrate. Fingerstick blood glucose was measured at 0, 15, 30, 45, 60, 90, and 120 min after consumption following a fasting state. The GI was calculated using the standard equation. The GI values for test foods ranged from 96 to 116 and were all classified as high GI foods. No difference in GI was found between American-grown and Thailand-grown jasmine rice. Although not statistically significant, observations show glycemic response among Asian American participants may be different. GI should be considered when planning meals with jasmine rice as the main source carbohydrate.

  14. Enteric Micromotor Can Selectively Position and Spontaneously Propel in the Gastrointestinal Tract.

    PubMed

    Li, Jinxing; Thamphiwatana, Soracha; Liu, Wenjuan; Esteban-Fernández de Ávila, Berta; Angsantikul, Pavimol; Sandraz, Elodie; Wang, Jianxing; Xu, Tailin; Soto, Fernando; Ramez, Valentin; Wang, Xiaolei; Gao, Weiwei; Zhang, Liangfang; Wang, Joseph

    2016-09-22

    The gastrointestinal (GI) tract, which hosts hundreds of bacteria species, becomes the most exciting organ for the emerging microbiome research. Some of these GI microbes are hostile and cause a variety of diseases. These bacteria colonize in different segments of the GI tract dependent on the local physicochemical and biological factors. Therefore, selectively locating therapeutic or imaging agents to specific GI segments is of significant importance for studying gut microbiome and treating various GI-related diseases. Herein, we demonstrate an enteric micromotor system capable of precise positioning and controllable retention in desired segments of the GI tract. These motors, consisting of magnesium-based tubular micromotors coated with an enteric polymer layer, act as a robust nanobiotechnology tool for site-specific GI delivery. The micromotors can deliver payload to a particular location via dissolution of their enteric coating to activate their propulsion at the target site toward localized tissue penetration and retention.

  15. Virulence of Japanese Encephalitis Virus Genotypes I and III, Taiwan

    PubMed Central

    Fan, Yi-Chin; Lin, Jen-Wei; Liao, Shu-Ying; Chen, Jo-Mei; Chen, Yi-Ying; Chiu, Hsien-Chung; Shih, Chen-Chang; Chen, Chi-Ming; Chang, Ruey-Yi; King, Chwan-Chuen; Chen, Wei-June; Ko, Yi-Ting; Chang, Chao-Chin

    2017-01-01

    The virulence of genotype I (GI) Japanese encephalitis virus (JEV) is under debate. We investigated differences in the virulence of GI and GIII JEV by calculating asymptomatic ratios based on serologic studies during GI- and GIII-JEV endemic periods. The results suggested equal virulence of GI and GIII JEV among humans. PMID:29048288

  16. The Galactic Isotropic γ-ray Background and Implications for Dark Matter

    NASA Astrophysics Data System (ADS)

    Campbell, Sheldon S.; Kwa, Anna; Kaplinghat, Manoj

    2018-06-01

    We present an analysis of the radial angular profile of the galacto-isotropic (GI) γ-ray flux-the statistically uniform flux in angular annuli centred on the Galactic centre. Two different approaches are used to measure the GI flux profile in 85 months of Fermi-LAT data: the BDS statistical method which identifies spatial correlations, and a new Poisson ordered-pixel method which identifies non-Poisson contributions. Both methods produce similar GI flux profiles. The GI flux profile is well-described by an existing model of bremsstrahlung, π0 production, inverse Compton scattering, and the isotropic background. Discrepancies with data in our full-sky model are not present in the GI component, and are therefore due to mis-modelling of the non-GI emission. Dark matter annihilation constraints based solely on the observed GI profile are close to the thermal WIMP cross section below 100 GeV, for fixed models of the dark matter density profile and astrophysical γ-ray foregrounds. Refined measurements of the GI profile are expected to improve these constraints by a factor of a few.

  17. Chemoprevention of Gastrointestinal Cancer: The Reality and the Dream

    PubMed Central

    Chun, Kyung-Soo; Kim, Eun-Hee; Lee, Sooyeon

    2013-01-01

    Despite substantial progress in screening, early diagnosis, and the development of noninvasive technology, gastrointestinal (GI) cancer remains a major cause of cancer-associated mortality. Chemoprevention is thought to be a realistic approach for reducing the global burden of GI cancer, and efforts have been made to search for chemopreventive agents that suppress acid reflux, GI inflammation and the eradication of Helicobacter pylori. Thus, proton pump inhibitors, statins, monoclonal antibodies targeting tumor necrosis factor-alpha, and nonsteroidal anti-inflammatory agents have been investigated for their potential to prevent GI cancer. Besides the development of these synthetic agents, a wide variety of the natural products present in a plant-based diet, which are commonly called phytoceuticals, have also sparked hope for the chemoprevention of GI cancer. To perform successful searches of chemopreventive agents for GI cancer, it is of the utmost importance to understand the factors contributing to GI carcinogenesis. Emerging evidence has highlighted the role of chronic inflammation in inducing genomic instability and telomere shortening and affecting polyamine metabolism and DNA repair, which may help in the search for new chemopreventive agents for GI cancer. PMID:23560148

  18. Effects of added PGX®, a novel functional fibre, on the glycaemic index of starchy foods.

    PubMed

    Brand-Miller, Jennie C; Atkinson, Fiona S; Gahler, Roland J; Kacinik, Veronica; Lyon, Michael R; Wood, Simon

    2012-07-01

    The development of lower-glycaemic index (GI) foods requires simple, palatable and healthy strategies. The objective of the present study was to determine the most effective dose of a novel viscous fibre supplement (PGX®) to be added to starchy foods to reduce their GI. Healthy subjects (n 10) consumed glucose sugar (50 g in water × 3) and six starchy foods with a range of GI values (52-72) along with 0 (inert fibre), 2.5 or 5 g granular PGX® dissolved in 250 ml water. GI testing according to ISO Standard 26,642-2010 was used to determine the reduction in GI. PGX® significantly reduced the GI of all six foods (P < 0.001), with an average reduction of 19 % for the 2.5 g dose and 30 % for the 5 g dose, equivalent to a reducing the GI by 7 and 15 units, respectively. Consuming small quantities of the novel functional fibre PGX®, mixed with water at the start of a meal, is an effective strategy to reduce the GI of common foods.

  19. Teaching a changing paradigm in physiology: a historical perspective on gut interstitial cells.

    PubMed

    Drumm, Bernard T; Baker, Salah A

    2017-03-01

    The study and teaching of gastrointestinal (GI) physiology necessitates an understanding of the cellular basis of contractile and electrical coupling behaviors in the muscle layers that comprise the gut wall. Our knowledge of the cellular origin of GI motility has drastically changed over the last 100 yr. While the pacing and coordination of GI contraction was once thought to be solely attributable to smooth muscle cells, it is now widely accepted that the motility patterns observed in the GI tract exist as a result of a multicellular system, consisting of not only smooth muscle cells but also enteric neurons and distinct populations of specialized interstitial cells that all work in concert to ensure proper GI functions. In this historical perspective, we focus on the emerging role of interstitial cells in GI motility and examine the key discoveries and experiments that led to a major shift in a paradigm of GI physiology regarding the role of interstitial cells in modulating GI contractile patterns. A review of these now classic experiments and papers will enable students and educators to fully appreciate the complex, multicellular nature of GI muscles as well as impart lessons on how shifting paradigms in physiology are fueled by new technologies that lead to new emerging discoveries. Copyright © 2017 the American Physiological Society.

  20. Disordered eating practices in gastrointestinal disorders.

    PubMed

    Satherley, R; Howard, R; Higgs, S

    2015-01-01

    To systematically review evidence concerning disordered eating practices in dietary-controlled gastrointestinal conditions. Three key questions were examined: a) are disordered eating practices a feature of GI disorders?; b) what abnormal eating practices are present in those with GI disorders?; and c) what factors are associated with the presence of disordered eating in those with GI disorders? By exploring these questions, we aim to develop a conceptual model of disordered eating development in GI disease. Five key databases, Web of Science with Conference Proceedings (1900-2014) and MEDLINE (1950-2014), PubMed, PsycINFO (1967-2014) and Google Scholar, were searched for papers relating to disordered eating practices in those with GI disorders. All papers were quality assessed before being included in the review. Nine papers were included in the review. The majority of papers reported that the prevalence of disordered eating behaviours is greater in populations with GI disorders than in populations of healthy controls. Disordered eating patterns in dietary-controlled GI disorders may be associated with both anxiety and GI symptoms. Evidence concerning the correlates of disordered eating was limited. The presence of disordered eating behaviours is greater in populations with GI disorders than in populations of healthy controls, but the direction of the relationship is not clear. Implications for further research are discussed. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. GI-SVM: A sensitive method for predicting genomic islands based on unannotated sequence of a single genome.

    PubMed

    Lu, Bingxin; Leong, Hon Wai

    2016-02-01

    Genomic islands (GIs) are clusters of functionally related genes acquired by lateral genetic transfer (LGT), and they are present in many bacterial genomes. GIs are extremely important for bacterial research, because they not only promote genome evolution but also contain genes that enhance adaption and enable antibiotic resistance. Many methods have been proposed to predict GI. But most of them rely on either annotations or comparisons with other closely related genomes. Hence these methods cannot be easily applied to new genomes. As the number of newly sequenced bacterial genomes rapidly increases, there is a need for methods to detect GI based solely on sequences of a single genome. In this paper, we propose a novel method, GI-SVM, to predict GIs given only the unannotated genome sequence. GI-SVM is based on one-class support vector machine (SVM), utilizing composition bias in terms of k-mer content. From our evaluations on three real genomes, GI-SVM can achieve higher recall compared with current methods, without much loss of precision. Besides, GI-SVM allows flexible parameter tuning to get optimal results for each genome. In short, GI-SVM provides a more sensitive method for researchers interested in a first-pass detection of GI in newly sequenced genomes.

  2. The association of gastrointestinal symptoms with weight, diet, and exercise in weight-loss program participants.

    PubMed

    Levy, Rona L; Linde, Jennifer A; Feld, Kayla A; Crowell, Michael D; Jeffery, Robert W

    2005-10-01

    Studies on the relationship between gastrointestinal (GI) symptoms and obesity are limited. Research on the relationship between GI symptoms (including irritable bowel syndrome [IBS]), weight, and weight-related behaviors are rare. This study assessed rates of GI symptoms in a sample of obese patients in a weight-loss program and explored relationships among GI symptoms and obesity, binge eating, dieting (fat and fruit/fiber consumption), and physical activity. A total of 983 participants (70% women) had a mean body mass index (BMI) of 33.2+/-5.7 kg/m2 (range, 25.1-60.8 kg/m2) and a mean age of 52.7+/-12.4 years (range, 20.4-89.8 y). Participants completed a questionnaire about diet and physical activity and a standardized self-report Rome II questionnaire assessing IBS status and GI symptoms. In bivariate analyses BMI was associated positively with abdominal pain and diarrhea whereas healthier diet (lower fat and higher fruit/fiber intake) and higher physical activity were associated with fewer GI symptoms. In multivariate models BMI was not associated with GI symptoms; physical activity remained a protective factor. Although physiologic mechanisms still need to be explored, associations between GI symptoms and diet and exercise behaviors may have implications for the treatment of both obesity and GI symptoms.

  3. Postprandial gastrointestinal blood flow, oxygen consumption and heart rate in rainbow trout (Oncorhynchus mykiss).

    PubMed

    Eliason, Erika J; Higgs, David A; Farrell, Anthony P

    2008-04-01

    The present study is the first to simultaneously and continuously measure oxygen consumption (MO(2)) and gastrointestinal blood flow (q(gi)) in fish. In addition, while it is the first to compare the effects of three isoenergetic diets on q(gi) in fish, no significant differences among diets were found for postprandial MO(2), q(gi) or heart rate (f(H)) in rainbow trout, Oncorhynchus mykiss. Postprandial q(gi), f(H) and MO(2) were significantly elevated above baseline levels by 4 h. Postprandial q(gi) peaked at 136% above baseline after 11 h, f(H) peaked at 110% above baseline after 14 h and MO(2) peaked at 96% above baseline after 27 h. Moreover, postprandial MO(2) remained significantly elevated above baseline longer than q(gi) (for 41 h and 30 h, respectively), perhaps because most of the increase in MO(2) associated with feeding is due to protein handling, a process that continues following the absorption of nutrients which is thought to be the primary reason for the elevation of q(gi). In addition to the positive relationships found between postprandial MO(2) and q(gi) and between postprandial MO(2) and f(H), we discovered a novel relationship between postprandial q(gi) and f(H).

  4. AUTO_DERIV: Tool for automatic differentiation of a Fortran code

    NASA Astrophysics Data System (ADS)

    Stamatiadis, S.; Farantos, S. C.

    2010-10-01

    AUTO_DERIV is a module comprised of a set of FORTRAN 95 procedures which can be used to calculate the first and second partial derivatives (mixed or not) of any continuous function with many independent variables. The mathematical function should be expressed as one or more FORTRAN 77/90/95 procedures. A new type of variables is defined and the overloading mechanism of functions and operators provided by the FORTRAN 95 language is extensively used to define the differentiation rules. Proper (standard complying) handling of floating-point exceptions is provided by using the IEEE_EXCEPTIONS intrinsic module (Technical Report 15580, incorporated in FORTRAN 2003). New version program summaryProgram title: AUTO_DERIV Catalogue identifier: ADLS_v2_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADLS_v2_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 2963 No. of bytes in distributed program, including test data, etc.: 10 314 Distribution format: tar.gz Programming language: Fortran 95 + (optionally) TR-15580 (Floating-point exception handling) Computer: all platforms with a Fortran 95 compiler Operating system: Linux, Windows, MacOS Classification: 4.12, 6.2 Catalogue identifier of previous version: ADLS_v1_0 Journal reference of previous version: Comput. Phys. Comm. 127 (2000) 343 Does the new version supersede the previous version?: Yes Nature of problem: The need to calculate accurate derivatives of a multivariate function frequently arises in computational physics and chemistry. The most versatile approach to evaluate them by a computer, automatically and to machine precision, is via user-defined types and operator overloading. AUTO_DERIV is a Fortran 95 implementation of them, designed to evaluate the first and second derivatives of a function of many variables. Solution method: The mathematical rules for differentiation of sums, products, quotients, elementary functions in conjunction with the chain rule for compound functions are applied. The function should be expressed as one or more Fortran 77/90/95 procedures. A new type of variables is defined and the overloading mechanism of functions and operators provided by the Fortran 95 language is extensively used to implement the differentiation rules. Reasons for new version: The new version supports Fortran 95, handles properly the floating-point exceptions, and is faster due to internal reorganization. All discovered bugs are fixed. Summary of revisions:The code was rewritten extensively to benefit from features introduced in Fortran 95. Additionally, there was a major internal reorganization of the code, resulting in faster execution. The user interface described in the original paper was not changed. The values that the user must or should specify before compilation (essentially, the number of independent variables) were moved into ad_types module. There were many minor bug fixes. One important bug was found and fixed; the code did not handle correctly the overloading of ∗ in aλ when a=0. The case of division by zero and the discontinuity of the function at the requested point are indicated by standard IEEE exceptions ( IEEE_DIVIDE_BY_ZERO and IEEE_INVALID respectively). If the compiler does not support IEEE exceptions, a module with the appropriate name is provided, imitating the behavior of the 'standard' module in the sense that it raises the corresponding exceptions. It is up to the compiler (through certain flags probably) to detect them. Restrictions: None imposed by the program. There are certain limitations that may appear mostly due to the specific implementation chosen in the user code. They can always be overcome by recoding parts of the routines developed by the user or by modifying AUTO_DERIV according to specific instructions given in [1]. The common restrictions of available memory and the capabilities of the compiler are the same as the original version. Additional comments: The program has been tested using the following compilers: Intel ifort, GNU gfortran, NAGWare f95, g95. Running time: The typical running time for the program depends on the compiler and the complexity of the differentiated function. A rough estimate is that AUTO_DERIV is ten times slower than the evaluation of the analytical ('by hand') function value and derivatives (if they are available). References:S. Stamatiadis, R. Prosmiti, S.C. Farantos, AUTO_DERIV: tool for automatic differentiation of a Fortran code, Comput. Phys. Comm. 127 (2000) 343.

  5. The glycemic index: methodological aspects related to the interpretation of health effects and to regulatory labeling.

    PubMed

    Aziz, Alfred

    2009-01-01

    The glycemic index (GI) is an experimental system that classifies carbohydrates (CHO) and CHO-containing foods according to their blood glucose-raising potential. It is based on the glycemic response following the ingestion of a test food containing a defined amount of available CHO relative to that of an equi-carbohydrate portion of either white bread or glucose. The concept has been extended to mixed meals and whole diets where the GI of the meal/diet is expressed as the weighted average of the GI of each food, based on the percentage of the total mealldiet CHO provided by each food. Over the last few decades, a substantial number of epidemiological and interventional studies have reported beneficial associationsleffects of lower GI diets across a wide spectrum of pathophysiological conditions, including diabetes, cardiovascular disease, obesity, and certain forms of cancer. This has prompted proponents of the GI to recommend its use for dietary planning and labeling purposes. However, the currently recommended GI methodology is not well standardized and has several flaws, which brings into question the strength of evidence attributed to the health effects of low-GI diets. This review focuses exclusively on the methodological aspects of the GI, how they might impact the interpretation of data related to the purported health benefits of low GI diets, and the considerations for the use of the GI in food labeling. In addition, alternative systems for classifying the glycemic effects of CHO-containing foods are briefly discussed.

  6. Pretreatment with diphenoxylate hydrochloride/atropine sulfate (Lomotil) does not decrease physiologic bowel FDG activity on PET/CT scans of the abdomen and pelvis.

    PubMed

    Murphy, Robert; Doerger, Kirk M; Nathan, Mark A; Lowe, Val J

    2009-01-01

    Physiologic uptake of 2-[(18)F]-fluoro-2-deoxy-D: -glucose (FDG) by bowel can confound positron emission tomography/computed tomography (PET/CT) assessment for abdominal pathology, particularly within the bowel itself. We wished to determine if oral administration of the antimotility agent, Lomotil (5 mg diphenoxylate hydrochloride/0.05 mg atropine sulfate; G.D. Searle and Company, a division of Pfizer), prior to PET/CT scanning would reduce physiologic uptake of FDG by the small bowel and colon (lower gastrointestinal [GI] tract). Patients undergoing PET/CT scans for lymphoma were enrolled in a prospective, randomized, double-blinded study and received either 10 mL water (control group) or 10 mL Lomotil (experimental group) orally 30-60 min prior to scanning. Scans were reviewed independently by two blinded experienced readers and scored for the degree of FDG activity in the lower GI tract relative to liver activity. The administration of Lomotil prior to PET/CT scanning did not reduce physiologic FDG activity in the small bowel and colon. In contrast, increased radiotracer uptake by the lower GI tract was observed in the Lomotil group compared to the control group. Pretreatment with Lomotil prior to PET/CT scanning confers no benefit toward the reduction of physiologic FDG uptake by the small bowel and colon.

  7. Experimental single-strain mobilomics reveals events that shape pathogen emergence.

    PubMed

    Schoeniger, Joseph S; Hudson, Corey M; Bent, Zachary W; Sinha, Anupama; Williams, Kelly P

    2016-08-19

    Virulence genes on mobile DNAs such as genomic islands (GIs) and plasmids promote bacterial pathogen emergence. Excision is an early step in GI mobilization, producing a circular GI and a deletion site in the chromosome; circular forms are also known for some bacterial insertion sequences (ISs). The recombinant sequence at the junctions of such circles and deletions can be detected sensitively in high-throughput sequencing data, using new computational methods that enable empirical discovery of mobile DNAs. For the rich mobilome of a hospital Klebsiella pneumoniae strain, circularization junctions (CJs) were detected for six GIs and seven IS types. Our methods revealed differential biology of multiple mobile DNAs, imprecision of integrases and transposases, and differential activity among identical IS copies for IS26, ISKpn18 and ISKpn21 Using the resistance of circular dsDNA molecules to exonuclease, internally calibrated with the native plasmids, showed that not all molecules bearing GI CJs were circular. Transpositions were also detected, revealing replicon preference (ISKpn18 prefers a conjugative IncA/C2 plasmid), local action (IS26), regional preferences, selection (against capsule synthesis) and IS polarity inversion. Efficient discovery and global characterization of numerous mobile elements per experiment improves accounting for the new gene combinations that arise in emerging pathogens. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  8. Efficacy and Clinical Outcomes of Transcatheter Arterial Embolization for Gastrointestinal Bleeding from Gastrointestinal Stromal Tumor.

    PubMed

    Koo, Hyun Jung; Shin, Ji Hoon; Shin, Sooyoung; Yoon, Hyun-Ki; Ko, Gi-Young; Gwon, Dong Il

    2015-09-01

    To evaluate the efficacy and clinical outcomes of transcatheter arterial embolization (TAE) for gastrointestinal (GI) bleeding from gastrointestinal stromal tumor (GIST). TAE was performed in 20 referred patients (male:female = 13:7; median age, 56.3 y) for GI bleeding from GISTs. The locations of GISTs were assessed using contrast-enhanced computed tomography (CT) and catheter angiography. The technical and clinical success of TAE and clinical outcomes including procedure-related complications, recurrent bleeding, 30-day and overall mortality, and cumulative survival were evaluated. The sites of GIST-related bleeding or tumor staining were the jejunum (n = 9), stomach (n = 5), ileum (n = 3), duodenum (n = 2), and jejunum and colon (n = 1). Angiography showed bleeding from GIST in 5 patients, and tumor staining was noted in only 15 patients. TAE was performed for patients with and without contrast medium extravasation on angiography. Technical and clinical success rates of TAE were 95% (19 of 20 patients) and 90% (18 of 20 patients), respectively. Recurrent bleeding was noted in 1 patient. There were no procedure-related complications. In 15 patients, surgical resection of the tumors was performed after TAE. The 30-day and overall mortality rates were 10% (2 of 20 patients) and 30% (6 of 20 patients), respectively. TAE is a safe and effective method for controlling GI bleeding from the GIST. Copyright © 2015 SIR. Published by Elsevier Inc. All rights reserved.

  9. Gastrointestinal side effects in postmenopausal women using osteoporosis therapy: 1-year findings in the POSSIBLE US study.

    PubMed

    Woo, Claudine; Gao, Guozhi; Wade, Sally; Hochberg, Marc C

    2010-04-01

    To characterize gastrointestinal side effects (GI SEs) and its associations with medication discontinuation, health-related quality of life (HRQoL), and treatment) satisfaction in postmenopausal women prescribed osteoporosis (OP) therapies. Prospective Observational Scientific Study Investigating Bone Loss Experience (POSSIBLE US*) participants enrolled October 27, 2004 - January 25, 2007 and complete questionnaires for up to 3 years. GI SEs for women new to or stable on therapy at entry were characterized at 6 and 12 months. Adjusted odds of experiencing GI SEs; mean HRQoL and treatment satisfaction scores; and risk of discontinuing therapy for bisphosphonate (BP) versus non-BP users were compared with logistic and generalized linear models. About 20% of women reported >or=1 GI SE at entry. GI SEs at month 6 were more common in BP than non-BP users (new: OR = 1.5, 95% CI: 1.2-2.0; stable: OR = 1.7, 95% CI: 1.3-2.1). Women new to OP therapy with GI SEs at month 6 had lower LS Mean HRQoL (OPAQ-SV Emotional Status: 72.3 vs. 78.2, p = 0.005) and treatment satisfaction scores (SEs: 71.4 vs. 82.9; 58.6 vs. 65.6; Global: 55.0 vs. 64.4; all p

  10. Yogurt Is a Low-Glycemic Index Food.

    PubMed

    Wolever, Thomas Ms

    2017-07-01

    High yogurt intake is associated with a reduced risk of type 2 diabetes (T2DM). Although several mechanisms could explain this association, this paper addresses the glycemic and insulinemic impact of yogurt. There is evidence that low-glycemic index (GI) and low-glycemic load (GL) diets are associated with a reduced risk of T2DM. The 93 GI values for yogurt in the University of Sydney's GI database have a mean ± SD of 34 ± 13, and 92% of the yogurts are low-GI (≤55). The 43 plain yogurts in the database have a lower GI than the 50 sweetened yogurts, 27 ± 11 compared with 41 ± 11 ( P < 0.0001). This difference is not explained by sugar, per se, but rather by the higher protein-to-carbohydrate ratio in plain yogurt. Although yogurt has a low GI, its insulinemic index (II) is higher than its GI. High insulin responses may be deleterious because hyperinsulinemia is associated with an increased risk of T2DM. Nevertheless, this may not be a concern for yogurt because, although its II is higher than its GI, the II of yogurt is within the range of II values for nondairy low-GI foods. In addition, mixed meals containing dairy protein elicit insulin responses similar to those elicited by mixed meals of similar composition containing nondairy protein. Because the GI of yogurt is lower than that of most other carbohydrate foods, exchanging yogurt for other protein and carbohydrate sources can reduce the GI and GL of the diet, and is in line with recommended dietary patterns, which include whole grains, fruits, vegetables, nuts, legumes, fish, vegetable oils, and yogurt. © 2017 American Society for Nutrition.

  11. Reduction of gastrointestinal symptoms in Parkinson's disease after a switch from oral therapy to rotigotine transdermal patch: a non-interventional prospective multicenter trial.

    PubMed

    Woitalla, Dirk; Kassubek, Jan; Timmermann, Lars; Lauterbach, Thomas; Berkels, Reinhard; Grieger, Frank; Müller, Thomas

    2015-03-01

    Gastrointestinal (GI) symptoms are common among patients with Parkinson's disease (PD), due to both the disease itself and anti-PD drugs. We hypothesized that transdermal drug administration may result in fewer GI problems. This prospective observational study (ClinicalTrials.gov: NCT01159691) investigated effect of switching to rotigotine transdermal patch from oral anti-PD medications in patients with PD and existing GI symptoms. Patients were enrolled if their physician was planning to switch them to rotigotine because of GI symptoms experienced while receiving oral anti-PD medications. Effectiveness assessments included a visual analog scale (VAS) measuring intensity of GI symptoms from 0 (no disorder) to 100 mm (extremely severe disorder), a questionnaire on the frequency and intensity of six individual GI complaints (heartburn, bloating, nausea, vomiting, abdominal pain, diarrhea), each rated 0-12 for a sum score of 0-72, and patient satisfaction regarding GI symptoms over approximately 6 weeks after switching. Of 75 patients who received rotigotine, 58 had follow-up data available for final analysis. Intensity of GI complaints improved numerically on both the VAS (47.5 ± 24.4 mm [n = 65] at baseline, 19.7 ± 23.3 mm [n = 58] after around 6 weeks) and the sum score of GI complaints (11.2 ± 9.0 at baseline, 2.1 ± 4.4 [n = 58] after around 6 weeks). Fifty of 58 patients were "satisfied" or "very satisfied" regarding GI symptoms over around 6 weeks following switch to the patch. This study suggests that a switch from oral anti-PD medications to rotigotine transdermal patch may improve existing GI symptoms among patients with PD. Additional controlled studies are needed to confirm this finding. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. The risk of gastrointestinal bleeding in patients receiving dabigatran etexilate: a systematic review and meta-analysis of the literature.

    PubMed

    Di Minno, Matteo Nicola Dario; Ambrosino, Pasquale; Di Minno, Alessandro; Tremoli, Elena; Di Minno, Giovanni

    2017-06-01

    Evidence on the risk of gastrointestinal (GI) bleeding associated with dabigatran etexilate (DE) is contrasting. We performed a meta-analysis of literature to address this issue. Studies on GI bleeding risk in patients receiving DE or vitamin-K antagonists (VKA) were systematically searched. Twenty-three studies (26 datasets) showed no difference in the GI bleeding risk between the 250,871 patients treated with DE and the 460,386 receiving VKA (OR: 1.052, 95% CI: 0.815, 1.359). Similar results were obtained when pooling together adjusted ORs/HRs, obtained by means of multivariate analysis (OR: 1.06, 95% CI: 0.914, 1.222). Compared with VKA, DE use was associated with a significantly lower risk of upper GI (OR: 0.742, 95% CI: 0.569, 0.968), but not of lower GI bleedings (OR: 1.208, 95% CI: 0.902, 1.619). Furthermore, no significant difference in the GI bleeding risk was found when data on DE 110 mg and DE 150 mg twice-daily were separately compared with VKA. No difference in GI bleeding risk was found between DE and VKA. These results were confirmed for both dosages of DE and when specifically analyzing lower GI bleeding. In contrast, the risk of upper GI bleeding was lower with DE than with VKA. KEY MESSAGES No difference in the risk of gastrointestinal (GI) bleeding can be found between dabigatran etexilate (DE) and vitamin K-antagonists (VKA). These results are confirmed for both dosages of DE. The risk of upper GI bleeding is lower with DE than with VKA.

  13. Abdominal symptoms during physical exercise and the role of gastrointestinal ischaemia: a study in 12 symptomatic athletes.

    PubMed

    ter Steege, Rinze W F; Geelkerken, Robert H; Huisman, Ad B; Kolkman, Jeroen J

    2012-10-01

    Gastrointestinal (GI) symptoms during exercise may be caused by GI ischaemia. The authors report their experience with the diagnostic protocol and management of athletes with symptomatic exercise-induced GI ischaemia. The value of prolonged exercise tonometry in the diagnostic protocol of these patients was evaluated. Patients referred for GI symptoms during physical exercise underwent a standardised diagnostic protocol, including prolonged exercise tonometry. Indicators of GI ischaemia, as measured by tonometry, were related to the presence of symptoms during the exercise test (S+ and S- tests) and exercise intensity. 12 athletes were specifically referred for GI symptoms during exercise (five males and seven females; median age 29 years (range 15-46 years)). Type of sport was cycling, long-distance running and triathlon. Median duration of symptoms was 32 months (range 7-240 months). Splanchnic artery stenosis was found in one athlete. GI ischaemia was found in six athletes during submaximal exercise. All athletes had gastric and jejunal ischaemia during maximum intensity exercise. No significant difference was found in gastric and jejunal Pco(2) or gradients between S+ and S- tests during any phase of the exercise protocol. In S+ tests, but not in S- tests, a significant correlation between lactate and gastric gradient was found. In S+ tests, the regression coefficients of gradients were higher than those in S- tests. Treatment advice aimed at limiting GI ischaemia were successful in reducing complaints in the majority of the athletes. GI ischaemia was present in all athletes during maximum intensity exercise and in 50% during submaximal exercise. Athletes with GI symptoms had higher gastric gradients per mmol/l increase in lactate, suggesting an increased susceptibility for the development of ischaemia during exercise. Treatment advice aimed at limiting GI ischaemia helped the majority of the referred athletes to reduce their complaints. Our results suggest an important role for GI ischaemia in the pathophysiology of their complaints.

  14. Clinical features and outcomes of systemic amyloidosis with gastrointestinal involvement: a single-center experience

    PubMed Central

    Lim, A Young; Lee, Ji Hyeon; Jung, Ki Sun; Gwag, Hye Bin; Kim, Do Hee; Kim, Seok Jin; Lee, Ga Yeon; Kim, Jung Sun; Kim, Hee-Jin; Lee, Soo-Youn; Lee, Jung Eun; Jeon, Eun-Seok

    2015-01-01

    Background/Aims The gastrointestinal (GI) tract often becomes involved in patients with systemic amyloidosis. As few GI amyloidosis data have been reported, we describe the clinical features and outcomes of patients with pathologically proven GI amyloidosis. Methods We identified 155 patients diagnosed with systemic amyloidosis between April 1995 and April 2013. Twenty-four patients (15.5%) were diagnosed with GI amyloidosis using associated symptoms, and the diagnoses were confirmed by direct biopsy. Results Among the 24 patients, 20 (83.3%) had amyloidosis light chain (AL), three (12.5%) had amyloid A, and one (4.2%) had transthyretin-related type amyloidosis. Their median age was 57 years (range, 37 to 72), and 10 patients were female (41.7%). The most common symptoms of GI amyloidosis were diarrhea (11 patients, 45.8%), followed by anorexia (nine patients, 37.5%), weight loss, and nausea and/or vomiting (seven patients, 29.2%). The histologically confirmed GI tract site in AL amyloidosis was the stomach in 11 patients (55.0%), the colon in nine (45.0%), the rectum in seven (35.0%), and the small bowel in one (5.0%). Patients with GI involvement had a greater frequency of organ involvement (p = 0.014). Median overall survival (OS) in patients with GI involvement was shorter (7.95 months; range, 0.3 to 40.54) than in those without GI involvement (15.84 months; range, 0.0 to 114.53; p = 0.069) in a univariate analysis. A multivariate analysis of prognostic factors for AL amyloidosis revealed that GI involvement was not a significant predictor of OS (p = 0.447). Conclusions The prognosis of patients with AL amyloidosis and GI involvement was poorer than those without GI involvement, and they presented with more organ involvement and more advanced disease than those without organ involvement. PMID:26161016

  15. Lowering dietary glycaemic index through nutrition education among Malaysian women with a history of gestational diabetes mellitus.

    PubMed

    Sangeetha-Shyam; Fatimah, A; Rohana, A G; Norasyikin, A W; Karuthan, C; Nik, Shanita S; Mohd, Yusof B N; Nor, Azmi K

    2013-04-01

    Gestational diabetes mellitus (GDM) increases risks for type 2 diabetes and cardiovascular diseases. Low glycaemic index (GI) diets improve cardio-metabolic outcomes in insulin-resistant individuals. We examined the feasibility of lowering GI through GI-based-education among Asian post-GDM women. A 3-month investigation was carried out on 60 Malaysian women with a mean age of 31.0 +/- 4.5 years and a history of GDM. Subjects were randomised into two groups: LGIE and CHDR. The CHDR group received conventional healthy dietary recommendations only. The LGIE group received GI based-education in addition to conventional healthy dietary recommendations. At baseline and after 3-months, dietary intake of energy and macronutrient intakes including GI diet and glycaemic load was assessed using 3-day food records. Diabetes-Diet and GI-concept scores and physical activity levels were assessed using a questionnaire. Adherence to dietary instructions was measured at the end of 3 months. At the end of 3 months, the LGIE group had significant reductions in energy intake (241.7 +/- 522.4Kcal, P = 0.037, ES=0.463), total carbohydrate (48.7 +/- 83.5g, P = 0.010, ES = 0.583), GI (3.9 +/- 7.1, P = 0.017, ES = 0.549) and GL (39.0 +/- 55.3, P = 0.003, ES = 0.705) and significant increases in protein (3.7 +/- 5.4g, 0.003, ES = 0.685) and diet fibre (4.6 +/- 7.3g, P = 0.06). The CHDR group had a significant reduction in fat only (5.7 +/- 9.4g, P = 0.006, ES = 0.606). There was a 30% increase in GI-concept scores in the LGIE group (p < 0.001). Changes in GI-concept scores correlated significantly to the reduction in dietary GI (r = -0.642, P = 0.045). Dietary adherence was comparable in both groups. GI-education improves GI-concept knowledge and helps lower dietary glycaemic index among women with a history of GDM.

  16. Is It Okay To Ask: Transgender Patient Perspectives on Sexual Orientation and Gender Identity Collection in Healthcare.

    PubMed

    Maragh-Bass, Allysha C; Torain, Maya; Adler, Rachel; Ranjit, Anju; Schneider, Eric; Shields, Ryan Y; Kodadek, Lisa M; Snyder, Claire F; German, Danielle; Peterson, Susan; Schuur, Jeremiah; Lau, Brandyn D; Haider, Adil H

    2017-06-01

    The National Academy of Medicine and Joint Commission recommend routine documentation of sexual orientation (SO) and gender identity (GI) in healthcare to address lesbian, gay, bisexual, or transgender (LGBT) health disparities. We explored transgender patient-reported views on the importance on SO/GI collection, their willingness to disclose, and their perceived facilitators of SO/GI collection in primary care and emergency department (ED) settings. We recruited a national sample of self-identified transgender patients. Participants completed demographic questions, survey questions, and free-response comments regarding their views on SO/GI collection. Data were analyzed using descriptive statistics; inductive content analysis was conducted with open-ended responses. Patients mostly self-identified as male gender (54.5%), white (58.4%), and SO other than heterosexual or LGB (33.7%; N = 101). Patients felt that it was more important for primary care providers to know their GI than SO (89.1% vs. 57%; p < 0.001); there was no difference among reported importance for ED providers to know the patients' SO versus GI. Females were more likely than males to report medical relevance to chief complaint as a facilitator to SO disclosure (89.1% vs. 80%; p = 0.02) and less likely to identify routine collection from all patients as a facilitator to GI disclosure (67.4% vs. 78.2%; p = 0.09). Qualitatively, many patients reported that medical relevance to chief complaint and an LGBT-friendly environment would increase willingness to disclose their SO/GI. Patients also reported need for educating providers in LGBT health prior to implementing routine SO/GI collection. Patients see the importance of providing GI more than SO to providers; nonetheless they are willing to disclose SO/GI in general.. Findings also suggest that gender differences may exist in facilitators of SO/GI disclosure. Given the underrepresentation of transgender patients in healthcare, it is crucial for providers to address their concerns with SO/GI disclosure, which include LGBT education for medical staff and provision of a safe environment. © 2017 by the Society for Academic Emergency Medicine.

  17. Glycaemic index of four commercially available breads in Malaysia.

    PubMed

    Yusof, Barakatun Nisak Mohd; Abd Talib, Ruzita; Karim, Norimah A; Kamarudin, Nor Azmi; Arshad, Fatimah

    2009-09-01

    This study was carried out to determine the blood glucose response and glycaemic index (GI) values of four types of commercially available breads in Malaysia. Twelve healthy volunteers (six men, six women; body mass index, 21.9±1.6 kg/m(2); age, 22.9±1.7 years) participated in this study. The breads tested were multi-grains bread (M-Grains), wholemeal bread (WM), wholemeal bread with oatmeal (WM-Oat) and white bread (WB). The subjects were studied on seven different occasions (four tests for the tested breads and three repeated tests of the reference food) after an overnight fast. Capillary blood samples were taken immediately before (0 min) and 15, 30, 45, 60, 90 and 120 min after consumption of the test foods. The blood glucose response was obtained by calculating the incremental area under the curve. The GI values were determined according to the standardized methodology. Our results showed that the M-Grains and WM-Oat could be categorized as intermediate GI while the WM and WB breads were high GI foods, respectively. The GI of M-Grains (56±6.2) and WM-Oat (67±6.9) were significantly lower than the reference food (glucose; GI = 100) (P < 0.05). No significant difference in GI value was seen between the reference food and the GI of WM (85±5.9) and WB (82±6.5) (P > 0.05). Among the tested breads, the GI values of M-Grains and WM-Oat were significantly lower (P < 0.05) than those of WM and WB. There was no relationship between the dietary fibre content of the bread with the incremental area under the curve (r = 0.15, P = 0.15) or their GI values (r = 0.17, P = 0.12), indicating that the GI value of the test breads were unaffected by the fibre content of the breads. The result of this study will provide useful nutritional information for dieticians and the public alike who may prefer low-GI over high-GI foods.

  18. Does the ingestion of a 24 hour low glycaemic index Asian mixed meal diet improve glycaemic response and promote fat oxidation? A controlled, randomized cross-over study.

    PubMed

    Camps, Stefan Gerardus; Kaur, Bhupinder; Quek, Rina Yu Chin; Henry, Christiani Jeyakumar

    2017-07-12

    The health benefits of consuming a low glycaemic index (GI) diet to reduce the risk of type 2 Diabetes are well recognized. In recent years the GI values of various foods have been determined. Their efficacy in constructing and consuming a low GI diet over 24 h in modulating glycaemic response has not been fully documented. The translation of using single-point GI values of foods to develop a 24 h mixed meal diet can provide valuable information to consumers, researchers and dietitians to optimize food choice for glycaemic control. By using GI values of foods to develop mixed meals, our study is the first to determine how both blood glucose and substrate oxidation may be modulated over 24 h. The study included 11 Asian men with a BMI between 17-24 kg/m 2 who followed both a 1-day low GI and 1-day high GI diet in a randomized, controlled cross-over design. Test meals included breakfast, lunch, snack and dinner. Glycaemic response was measured continuously for over 24 h and postprandial substrate oxidation for 10 h inside a whole body calorimeter. The low GI diet resulted in lower 24 h glucose iAUC (860 ± 440 vs 1329 ± 614 mmol/L.min; p = 0.014) with lower postprandial glucose iAUC after breakfast (p < 0.001), lunch (p = 0.009), snack (p = 0.012) and dinner (p = 0.003). Moreover, 24 h mean amplitude of glycaemic excursion was lower during the low GI vs high GI diet (1.44 ± 0.63 vs 2.33 ± 0.82 mmol/L; p < 0.001). Simultaneously, decrease in 10 h fat oxidation was less during the low vs high GI diet (-0.033 ± 0.021 vs -0.050 ± 0.017 g/min; p < 0.001), specifically after breakfast (p < 0.001) and lunch (p < 0.001). Our study corroborates that using low GI local foods to construct a 24 h low GI diet, is able to reduce glycaemic response and variability as recorded by continuous glucose monitoring. Our observations also confirm that a low GI diet promotes fat oxidation over carbohydrate oxidation when compared to a high GI diet. These observations provide public health support for the encouragement of healthier nutrition choices by consuming low GI foods. NCT 02631083 (Clinicaltrials.gov).

  19. An Improved Cross-Layering Design for IPv6 Fast Handover with IEEE 802.16m Entry Before Break Handover

    NASA Astrophysics Data System (ADS)

    Kim, Ronny Yongho; Jung, Inuk; Kim, Young Yong

    IEEE 802.16m is an advanced air interface standard which is under development for IMT-Advanced systems, known as 4G systems. IEEE 802.16m is designed to provide a high data rate and a Quality of Service (QoS) level in order to meet user service requirements, and is especially suitable for mobilized environments. There are several factors that have great impact on such requirements. As one of the major factors, we mainly focus on latency issues. In IEEE 802.16m, an enhanced layer 2 handover scheme, described as Entry Before Break (EBB) was proposed and adopted to reduce handover latency. EBB provides significant handover interruption time reduction with respect to the legacy IEEE 802.16 handover scheme. Fast handovers for mobile IPv6 (FMIPv6) was standardized by Internet Engineering Task Force (IETF) in order to provide reduced handover interruption time from IP layer perspective. Since FMIPv6 utilizes link layer triggers to reduce handover latency, it is very critical to jointly design FMIPv6 with its underlying link layer protocol. However, FMIPv6 based on new handover scheme, EBB has not been proposed. In this paper, we propose an improved cross-layering design for FMIPv6 based on the IEEE 802.16m EBB handover. In comparison with the conventional FMIPv6 based on the legacy IEEE 802.16 network, the overall handover interruption time can be significantly reduced by employing the proposed design. Benefits of this improvement on latency reduction for mobile user applications are thoroughly investigated with both numerical analysis and simulation on various IP applications.

  20. A High Performance Frequency Standard and Distribution System for Cassini Ka-Band Experiment

    DTIC Science & Technology

    2005-08-01

    Orthogonal Polarization In Anisotropic Dielectric Resonators”, Proceedings of the 2002 IEEE International Frequency Control Symposium , pp. 553-558...2002. [9] G. J. Dick, Rabi T. Wang, Robert Tjoelker, “Design and Progress Report for Compact Cryocooled Sapphire Oscillator "VCSO"”, Proc. 2005 Joint...IEEE FCS/ PTTI. [10] R. Basu, G. J. Dick, Rabi T. Wang,” Novel Design of an All- Cryogenic RF Pound Circuit “,Proc. 2005 Joint IEEE FCS/ PTTI

  1. Status of the Body of Knowledge and Curriculum to Advance Systems Engineering (BKCASE (trademark)) Project

    DTIC Science & Technology

    2011-10-01

    Systems engineer- ing knowledge has also been documented through the standards bodies, most notably : • ISO /IEC/IEEE 15288, Systems Engineer- ing...System Life Cycle Processes, 2008 (see [10]). • ANSI/EIA 632, Processes for Engineering a System, (1998) • IEEE 1220, ISO /IEC 26702 Application...tion • United States Defense Acquisition Guidebook, Chapter 4, June 27, 2011 • IEEE/EIA 12207 , Software Life Cycle Processes, 2008 • United

  2. Hierarchical Organization for Large, Dynamic Radio Networks.

    DTIC Science & Technology

    1988-01-01

    January 1985. [3] N. Shacharm and J. Tornow . Future Directions in Packet Radio Technology. In - Proc. of IEEE INFOCOM󈨙, Washington, D.C., 1985. [4] J.J...Freeman and Company, 1979. [7] J. Jubin and J. Tornow . The DARPA Packet Radio Network Protocols. Proceed- inga of the IEEE, 75(1):21-32, January 1987... Tornow . Future Directions in Packet Radio Technology. In Proc. of IEEE INFOCOM󈨙, Washington, D.C., 1985. [28] N. Shacham and J. Westcott. Future

  3. Watchdog Sensor Network with Multi-Stage RF Signal Identification and Cooperative Intrusion Detection

    DTIC Science & Technology

    2012-03-01

    detection and physical layer authentication in mobile Ad Hoc networks and wireless sensor networks (WSNs) have been investigated. Résume Le rapport...IEEE 802.16 d and e (WiMAX); (b) IEEE 802.11 (Wi-Fi) family of a, b, g, n, and s (c) Sensor networks based on IEEE 802.15.4: Wireless USB, Bluetooth... sensor network are investigated for standard compatible wireless signals. The proposed signal existence detection and identification process consists

  4. An NTP Stratum-One Server Farm Fed By IEEE-1588

    DTIC Science & Technology

    2010-01-01

    Serial Time Code Formats,” U.S. Army White Sands Missile Range, N.M. [11] J. Eidson , 2005, “IEEE-1588 Standard for a Precision Clock Synchronization ... synchronized to its Master Clocks via IRIG-B time code on a low- frequency RF distribution system. The availability of Precise Time Protocol (PTP, IEEE...forwarding back to the requestor. The farm NTP servers are synchronized to the USNO Master Clocks using IRIG-B time code. The current standard NTP

  5. Performance Evaluation of Glottal Inverse Filtering Algorithms Using a Physiologically Based Articulatory Speech Synthesizer

    DTIC Science & Technology

    2017-01-05

    1 Performance Evaluation of Glottal Inverse Filtering Algorithms Using a Physiologically Based Articulatory Speech Synthesizer Yu-Ren Chien, Daryush...D. Mehta, Member, IEEE, Jón Guðnason, Matías Zañartu, Member, IEEE, and Thomas F. Quatieri, Fellow, IEEE Abstract—Glottal inverse filtering aims to...of inverse filtering performance has been challenging due to the practical difficulty in measuring the true glottal signals while speech signals are

  6. Statistical Mechanics-Inspired Modeling of Heterogeneous Packet Transmission in Communication Networks

    DTIC Science & Technology

    2012-08-01

    Heterogeneous Packet Transmission in Communication Networks Soumik Sarkar, Member, IEEE, Kushal Mukherjee,Member, IEEE, Asok Ray , Fellow, IEEE...Dr. Mukherjee is a member of the American Society of Mechanical Engineers. Asok Ray (SM’83–F’02) received the graduate de- grees in each discipline of...United Technologies Research Center, East Hartford, CT 06108 USA (e-mail: sarkars@utrc.utc.com; srivasa1@utrc.utc.com). K. Mukherjee and A. Ray are with

  7. Advances in Systems and Technologies Toward Interopoerating Operational Military C2 and Simulation Systems

    DTIC Science & Technology

    2014-06-01

    Hieb, and R. Brown, “Standardizing Battle Management Language – A Vital Move Towards the Army Transformation,” paper 01S- SIW -067, IEEE Fall Simulation...Hieb, M., W. Sudnikovich, A. Tolk and J. Pullen, “Developing Battle Management Language into a Web Service,” paper 04S- SIW -113, IEEE Spring Simulation...Mediation and Data Storage,” paper 05S- SIW -019, IEEE Spring Simulation Interoperability Workshop, Orlando, FL, 2005 [6] Multilateral

  8. Algorithm XXX : functions to support the IEEE standard for binary floating-point arithmetic.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cody, W. J.; Mathematics and Computer Science

    1993-12-01

    This paper describes C programs for the support functions copysign(x,y), logb(x), scalb(x,n), nextafter(x,y), finite(x), and isnan(x) recommended in the Appendix to the IEEE Standard for Binary Floating-Point Arithmetic. In the case of logb, the modified definition given in the later IEEE Standard for Radix-Independent Floating-Point Arithmetic is followed. These programs should run without modification on most systems conforming to the binary standard.

  9. 77 FR 22068 - Proposed Information Collection (Post-9/11 GI Bill Education Longitudinal Study Survey) Activity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-12

    ... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-New (Post-9/11 GI Bill Longitudinal Study Survey)] Proposed Information Collection (Post-9/11 GI Bill Education Longitudinal Study Survey) Activity... information needed to determine the long-term outcomes of Veterans participating in VBA's Post-9/11GI Bill...

  10. 77 FR 39344 - Agency Information (Post-9/11 GI Bill Education Longitudinal Study Survey) Activity Under OMB Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-02

    ... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-New (Post-9/11 GI Bill Longitudinal Study Survey)] Agency Information (Post-9/11 GI Bill Education Longitudinal Study Survey) Activity Under OMB...-9/11 GI Bill Longitudinal Study Survey) in any correspondence For Further Information or a Copy of...

  11. Pulse-compression ghost imaging lidar via coherent detection.

    PubMed

    Deng, Chenjin; Gong, Wenlin; Han, Shensheng

    2016-11-14

    Ghost imaging (GI) lidar, as a novel remote sensing technique, has been receiving increasing interest in recent years. By combining pulse-compression technique and coherent detection with GI, we propose a new lidar system called pulse-compression GI lidar. Our analytical results, which are backed up by numerical simulations, demonstrate that pulse-compression GI lidar can obtain the target's spatial intensity distribution, range and moving velocity. Compared with conventional pulsed GI lidar system, pulse-compression GI lidar, without decreasing the range resolution, is easy to obtain high single pulse energy with the use of a long pulse, and the mechanism of coherent detection can eliminate the influence of the stray light, which is helpful to improve the detection sensitivity and detection range.

  12. Quantification of bone quality using different cone beam computed tomography devices: Accuracy assessment for edentulous human mandibles.

    PubMed

    Van Dessel, Jeroen; Nicolielo, Laura Ferreira Pinheiro; Huang, Yan; Slagmolen, Pieter; Politis, Constantinus; Lambrichts, Ivo; Jacobs, Reinhilde

    To determine the accuracy of the latest cone beam computed tomography (CBCT) machines in comparison to multi-slice computer tomography (MSCT) and micro computed tomography (micro-CT) for objectively assessing trabecular and cortical bone quality prior to implant placement. Eight edentulous human mandibular bone samples were scanned with seven CBCT scanners (3D Accuitomo 170, i-CAT Next Generation, ProMax 3D Max, Scanora 3D, Cranex 3D, Newtom GiANO and Carestream 9300) and one MSCT system (Somatom Definition Flash) using the clinical exposure protocol with the highest resolution. Micro-CT (SkyScan 1174) images served as a gold standard. A volume of interest (VOI) comprising trabecular and cortical bone only was delineated on the micro-CT. After spatial alignment of all scan types, micro-CT VOIs were overlaid on the CBCT and MSCT images. Segmentation was applied and morphometric parameters were calculated for each scanner. CBCT and MSCT morphometric parameters were compared with micro-CT using mixed-effect models. Intraclass correlation analysis was used to grade the accuracy of each scanner in assessing trabecular and cortical quality in comparison with the gold standard. Bone structure patterns of each scanner were compared with micro-CT in 2D and 3D to facilitate the interpretation of the morphometric analysis. Morphometric analysis showed an overestimation of the cortical and trabecular bone quantity during CBCT and MSCT evaluation compared to the gold standard micro-CT. The trabecular thickness (Tb.Th) was found to be significantly (P < 0.05) different and the smallest overestimation was found for the ProMax 3D Max (180 µm), followed by the 3D Accuitomo 170 (200 µm), Carestream 9300 (220 µm), Newtom GiANO (240 µm), Cranex 3D (280 µm), Scanora 3D (300 µm), high resolution MSCT (310 µm), i-CAT Next Generation (430 µm) and standard resolution MSCT (510 µm). The underestimation of the cortical thickness (Ct.Th) in ProMax 3D Max (-10 µm), the overestimation in Newtom GiANO (10 µm) and the high resolution MSCT (10 µm) were neglible. However, a significant overestimation (P < 0.05) was found for 3D Accuitomo 170 (110 µm), Scanora 3D (140 µm), standard resolution MSCT (150 µm), Carestream 9300 (190 µm), Cranex 3D (190 µm) and i-CAT Next Generation (230 µm). Comparison of the 2D network and 3D surface distance confirmed the overestimation in bone quantity, but only demonstrated a deviant trabecular network for the i-CAT Next Generation and the standard resolution MSCT. Intraclass correlation coefficients (ICCs) showed a significant (P < 0.05) high intra-observer reliability (ICC > 0.70) in morphometric evaluation between micro-CT and commercially available CBCT scanners (3D Accuitomo 170, Newtom GiANO and ProMax 3D Max). The ICC for Tb.Th and Ct.Th were 0.72 and 0.98 (3D Accuitomo 170), 0.71 and 0.96 (Newtom GiANO), and 0.87 and 0.92 (ProMax 3D Max), respectively. High resolution CBCT offers a clinical alternative to MSCT to objectively determine the bone quality prior to implant placement. However, not all tested CBCT machines have sufficient resolution to accurately depict the trabecular network or cortical bone. Conflict-of-interest statement: There is no conflict of interest to declare. Fellowship support came from Research Foundation Flanders (FWO) from the Belgian government, and Coordination for the Improvement of Higher Education Personnel (CAPES) program and Science without borders from the Brazilian government.

  13. Dynamic Information Management and Exchange for Command and Control Applications: A Framework in Support of Emergency Management for Specified and Unspecified Emergencies

    DTIC Science & Technology

    2014-03-01

    64 selections, 128 aggregations and 510 join operators . 0 100 200 300 400 500 600 700 800 900 1000 0 10 20 30 40 50 60 70 T im e...DC, USA, 2001, IEEE Computer So- ciety, pp. 391–398. [66] E. Network and I. S. A. (ENISA), Inventory of risk managemen - t /risk assessment methods, Sept... Operations and Reports (0704-0188), 1215 Jefferson Davis Highway, Suite 1204, Arlington, VA 22202-4302. Respondents should be aware that

  14. IEEE 1982. Proceedings of the international conference on cybernetics and society

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1982-01-01

    The following topics were dealt with: knowledge-based systems; risk analysis; man-machine interactions; human information processing; metaphor, analogy and problem-solving; manual control modelling; transportation systems; simulation; adaptive and learning systems; biocybernetics; cybernetics; mathematical programming; robotics; decision support systems; analysis, design and validation of models; computer vision; systems science; energy systems; environmental modelling and policy; pattern recognition; nuclear warfare; technological forecasting; artificial intelligence; the Turin shroud; optimisation; workloads. Abstracts of individual papers can be found under the relevant classification codes in this or future issues.

  15. Basic mathematical function libraries for scientific computation

    NASA Technical Reports Server (NTRS)

    Galant, David C.

    1989-01-01

    Ada packages implementing selected mathematical functions for the support of scientific and engineering applications were written. The packages provide the Ada programmer with the mathematical function support found in the languages Pascal and FORTRAN as well as an extended precision arithmetic and a complete complex arithmetic. The algorithms used are fully described and analyzed. Implementation assumes that the Ada type FLOAT objects fully conform to the IEEE 754-1985 standard for single binary floating-point arithmetic, and that INTEGER objects are 32-bit entities. Codes for the Ada packages are included as appendixes.

  16. Design of WLAN microstrip antenna for 5.17 - 5.835 GHz

    NASA Astrophysics Data System (ADS)

    Bugaj, Jarosław; Bugaj, Marek; Wnuk, Marian

    2017-04-01

    This paper presents the project of miniaturized WLAN Antenna made in microstrip technique working at a frequency of 5.17 - 5.835 GHz in 802.11ac IEEE standard. This dual layer antenna is designed on RT/duroid 5870 ROGERS CORPORATION substrate with dielectric constant 2.33 and thickness of 3.175 mm. The antenna parameters such as return loss, VSWR, gain and directivity are simulated and optimized using commercial computer simulation technology microwave studio (CST MWS). The paper presents the results of discussed numerical analysis.

  17. Dynamic Programming and Transitive Closure on Linear Pipelines.

    DTIC Science & Technology

    1984-05-01

    four partitions. 2.0 - 1.9 1.0t N. N 3N N -8 4 24 Figure41 An ideal solution to small problem sizes is to design an algorithm on an array where the...12 References [1] A.V. Aho, J. Hopcroft, and J.D. Ullman. The Design and Analysis of Computer Algorithms, Addison-Wesley, (1974). - " [2] R. Aubusson...K.E. Batcher, " Design of a Massively Parallel Processor," IEEE-TC, Vol. C-9, No. 9, (September, 1980), pp. 83-840. [4] K.Q. Brown, "Dynamic Programming

  18. A method for estimating the probability of lightning causing a methane ignition in an underground mine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sacks, H.K.; Novak, T.

    2008-03-15

    During the past decade, several methane/air explosions in abandoned or sealed areas of underground coal mines have been attributed to lightning. Previously published work by the authors showed, through computer simulations, that currents from lightning could propagate down steel-cased boreholes and ignite explosive methane/air mixtures. The presented work expands on the model and describes a methodology based on IEEE Standard 1410-2004 to estimate the probability of an ignition. The methodology provides a means to better estimate the likelihood that an ignition could occur underground and, more importantly, allows the calculation of what-if scenarios to investigate the effectiveness of engineering controlsmore » to reduce the hazard. The computer software used for calculating fields and potentials is also verified by comparing computed results with an independently developed theoretical model of electromagnetic field propagation through a conductive medium.« less

  19. Review and standardization of cell phone exposure calculations using the SAM phantom and anatomically correct head models.

    PubMed

    Beard, Brian B; Kainz, Wolfgang

    2004-10-13

    We reviewed articles using computational RF dosimetry to compare the Specific Anthropomorphic Mannequin (SAM) to anatomically correct models of the human head. Published conclusions based on such comparisons have varied widely. We looked for reasons that might cause apparently similar comparisons to produce dissimilar results. We also looked at the information needed to adequately compare the results of computational RF dosimetry studies. We concluded studies were not comparable because of differences in definitions, models, and methodology. Therefore we propose a protocol, developed by an IEEE standards group, as an initial step in alleviating this problem. The protocol calls for a benchmark validation study comparing the SAM phantom to two anatomically correct models of the human head. It also establishes common definitions and reporting requirements that will increase the comparability of all computational RF dosimetry studies of the human head.

  20. Review and standardization of cell phone exposure calculations using the SAM phantom and anatomically correct head models

    PubMed Central

    Beard, Brian B; Kainz, Wolfgang

    2004-01-01

    We reviewed articles using computational RF dosimetry to compare the Specific Anthropomorphic Mannequin (SAM) to anatomically correct models of the human head. Published conclusions based on such comparisons have varied widely. We looked for reasons that might cause apparently similar comparisons to produce dissimilar results. We also looked at the information needed to adequately compare the results of computational RF dosimetry studies. We concluded studies were not comparable because of differences in definitions, models, and methodology. Therefore we propose a protocol, developed by an IEEE standards group, as an initial step in alleviating this problem. The protocol calls for a benchmark validation study comparing the SAM phantom to two anatomically correct models of the human head. It also establishes common definitions and reporting requirements that will increase the comparability of all computational RF dosimetry studies of the human head. PMID:15482601

  1. Computational Physics? Some perspectives and responses of the undergraduate physics community

    NASA Astrophysics Data System (ADS)

    Chonacky, Norman

    2011-03-01

    Any of the many answers possible to the evocative question ``What is ...'' will likely be heavily shaded by the experience of the respondent. This is partly due to absence of a canon of practice in this still immature, hence dynamic and exciting, method of physics. The diversity of responses is even more apparent in the area of physics education, and more disruptive because an undergraduate educational canon uniformly accepted across institutions for decades already exists. I will present evidence of this educational community's lagging response to the challenge of the current dynamic and diverse practice of computational physics in research. I will also summarize current measures that attempt respond to this lag, discuss a researched-based approach for moving beyond these early measures, and suggest how DCOMP might help. I hope this will generate criticisms and concurrences from the floor. Research support for material in this talk was from: IEEE-Computer Society; Shodor Foundation; Teragrid Project.

  2. An efficient technique for the numerical solution of the bidomain equations.

    PubMed

    Whiteley, Jonathan P

    2008-08-01

    Computing the numerical solution of the bidomain equations is widely accepted to be a significant computational challenge. In this study we extend a previously published semi-implicit numerical scheme with good stability properties that has been used to solve the bidomain equations (Whiteley, J.P. IEEE Trans. Biomed. Eng. 53:2139-2147, 2006). A new, efficient numerical scheme is developed which utilizes the observation that the only component of the ionic current that must be calculated on a fine spatial mesh and updated frequently is the fast sodium current. Other components of the ionic current may be calculated on a coarser mesh and updated less frequently, and then interpolated onto the finer mesh. Use of this technique to calculate the transmembrane potential and extracellular potential induces very little error in the solution. For the simulations presented in this study an increase in computational efficiency of over two orders of magnitude over standard numerical techniques is obtained.

  3. Hybrid III-V Silicon Lasers

    NASA Astrophysics Data System (ADS)

    Bowers, John

    2014-03-01

    Abstract: A number of important breakthroughs in the past decade have focused attention on Si as a photonic platform. We review here recent progress in this field, focusing on efforts to make lasers, amplifiers, modulators and photodetectors on or in silicon. We also describe optimum quantum well design and distributed feedback cavity design to reduce the threshold and increase the efficiency and power output. The impact active silicon photonic integrated circuits could have on interconnects, telecommunications and on silicon electronics is reviewed. Biography: John Bowers holds the Fred Kavli Chair in Nanotechnology, and is the Director of the Institute for Energy Efficiency and a Professor in the Departments of Electrical and Computer Engineering and Materials at UCSB. He is a cofounder of Aurrion, Aerius Photonics and Calient Networks. Dr. Bowers received his M.S. and Ph.D. degrees from Stanford University and worked for AT&T Bell Laboratories and Honeywell before joining UC Santa Barbara. Dr. Bowers is a member of the National Academy of Engineering and a fellow of the IEEE, OSA and the American Physical Society. He is a recipient of the OSA/IEEE Tyndall Award, the OSA Holonyak Prize, the IEEE LEOS William Streifer Award and the South Coast Business and Technology Entrepreneur of the Year Award. He and coworkers received the EE Times Annual Creativity in Electronics (ACE) Award for Most Promising Technology for the hybrid silicon laser in 2007. Bowers' research is primarily in optoelectronics and photonic integrated circuits. He has published ten book chapters, 600 journal papers, 900 conference papers and has received 54 patents. He has published 180 invited papers and conference papers, and given 16 plenary talks at conferences. As well as Chong Zhang.

  4. Integrated Mission Simulation (IMSim): Multiphase Initialization Design with Late Joiners, Rejoiners and Federation Save & Restore

    NASA Technical Reports Server (NTRS)

    Dexter, Daniel E.; Varesic, Tony E.

    2015-01-01

    This document describes the design of the Integrated Mission Simulation (IMSim) federate multiphase initialization process. The main goal of multiphase initialization is to allow for data interdependencies during the federate initialization process. IMSim uses the High Level Architecture (HLA) IEEE 1516 [1] to provide the communication and coordination between the distributed parts of the simulation. They are implemented using the Runtime Infrastructure (RTI) from Pitch Technologies AB. This document assumes a basic understanding of IEEE 1516 HLA, and C++ programming. In addition, there are several subtle points in working with IEEE 1516 and the Pitch RTI that need to be understood, which are covered in Appendix A. Please note the C++ code samples shown in this document are for the IEEE 1516-2000 standard.

  5. Implicit Block ACK Scheme for IEEE 802.11 WLANs

    PubMed Central

    Sthapit, Pranesh; Pyun, Jae-Young

    2016-01-01

    The throughput of IEEE 802.11 standard is significantly bounded by the associated Medium Access Control (MAC) overhead. Because of the overhead, an upper limit exists for throughput, which is bounded, including situations where data rates are extremely high. Therefore, an overhead reduction is necessary to achieve higher throughput. The IEEE 802.11e amendment introduced the block ACK mechanism, to reduce the number of control messages in MAC. Although the block ACK scheme greatly reduces overhead, further improvements are possible. In this letter, we propose an implicit block ACK method that further reduces the overhead associated with IEEE 802.11e’s block ACK scheme. The mathematical analysis results are presented for both the original protocol and the proposed scheme. A performance improvement of greater than 10% was achieved with the proposed implementation.

  6. Talking about GI Disorders

    MedlinePlus

    ... Lifestyle Changes Strategies for Improving Bowel Habits Improving Sleep Quality Kids & Dietary Fiber Fruit Juice Surgery Laxatives Living with GI Disorders Talking About GI Disorders Personal Stories Social Security Benefits ...

  7. Gastrointestinal Side Effects of the Radioiodine Therapy for the Patients with Differentiated Thyroid Carcinoma Two Days after Prescription.

    PubMed

    Pashnehsaz, Mehran; Takavar, Abbas; Izadyar, Sina; Zakariaee, Seyed Salman; Mahmoudi, Mahmoud; Paydar, Reza; Geramifar, Parham

    2016-09-01

    Iodine-131 (I-131) therapy is one of the conventional approaches in the treatment of patients with differentiated thyroid carcinoma (DTC). The radioiodine agents also accumulate in the other organs that cause pain and damage to the patients. Radioiodine therapy is associated with various gastrointestinal (GI) toxicities. In this study, GI side effects of the radioiodine therapy were investigated. GI toxicities of the radioiodine therapy were studied in 137 patients with histologically proven DTC in Jun-Nov 2014. All the patients were treated by radioiodine agents in the research institute of Shariati Hospital, Tehran, Iran. The patients were examined 48 h after prescription (before discharge) and their GI side effects were registered. Correlation of the age, gender, administered dose, administered dose per body weight as the independent factors, and GI side effects were analyzed using the Pearson correlation test with Statistical Package for the Social Sciences (SPSS) version 20. Regression coefficients and linearity of the variable were investigated by MATLAB software. Line fitting was performed using MATLAB curve-fitting toolbox. From the subjects, 38 patients had GI complaints (30.4%). Significant factors influencing GI side effects were dose per body weight and administered doses. There was no significant correlation between age and gender as the independent parameters and GI complaints. The most prevalent GI side effect was nausea that occurs in 26.4% of the patients. From the results, it could be concluded that the GI side effects could be prevented by administering a safe radioiodine dose value less than 5,550 MBq.

  8. Methodology for adding glycemic index and glycemic load values to 24-hour dietary recall database.

    PubMed

    Olendzki, Barbara C; Ma, Yunsheng; Culver, Annie L; Ockene, Ira S; Griffith, Jennifer A; Hafner, Andrea R; Hebert, James R

    2006-01-01

    We describe a method of adding the glycemic index (GI) and glycemic load (GL) values to the nutrient database of the 24-hour dietary recall interview (24HR), a widely used dietary assessment. We also calculated daily GI and GL values from the 24HR. Subjects were 641 healthy adults from central Massachusetts who completed 9067 24HRs. The 24HR-derived food data were matched to the International Table of Glycemic Index and Glycemic Load Values. The GI values for specific foods not in the table were estimated against similar foods according to physical and chemical factors that determine GI. Mixed foods were disaggregated into individual ingredients. Of 1261 carbohydrate-containing foods in the database, GI values of 602 foods were obtained from a direct match (47.7%), accounting for 22.36% of dietary carbohydrate. GI values from 656 foods (52.1%) were estimated, contributing to 77.64% of dietary carbohydrate. The GI values from three unknown foods (0.2%) could not be assigned. The average daily GI was 84 (SD 5.1, white bread as referent) and the average GL was 196 (SD 63). Using this methodology for adding GI and GL values to nutrient databases, it is possible to assess associations between GI and/or GL and body weight and chronic disease outcomes (diabetes, cancer, heart disease). This method can be used in clinical and survey research settings where 24HRs are a practical means for assessing diet. The implications for using this methodology compel a broader evaluation of diet with disease outcomes.

  9. Crystal structure of glucose isomerase in complex with xylitol inhibitor in one metal binding mode.

    PubMed

    Bae, Ji-Eun; Kim, In Jung; Nam, Ki Hyun

    2017-11-04

    Glucose isomerase (GI) is an intramolecular oxidoreductase that interconverts aldoses and ketoses. These characteristics are widely used in the food, detergent, and pharmaceutical industries. In order to obtain an efficient GI, identification of novel GI genes and substrate binding/inhibition have been studied. Xylitol is a well-known inhibitor of GI. In Streptomyces rubiginosus, two crystal structures have been reported for GI in complex with xylitol inhibitor. However, a structural comparison showed that xylitol can have variable conformation at the substrate binding site, e.g., a nonspecific binding mode. In this study, we report the crystal structure of S. rubiginosus GI in a complex with xylitol and glycerol. Our crystal structure showed one metal binding mode in GI, which we presumed to represent the inactive form of the GI. The metal ion was found only at the M1 site, which was involved in substrate binding, and was not present at the M2 site, which was involved in catalytic function. The O 2 and O 4 atoms of xylitol molecules contributed to the stable octahedral coordination of the metal in M1. Although there was no metal at the M2 site, no large conformational change was observed for the conserved residues coordinating M2. Our structural analysis showed that the metal at the M2 site was not important when a xylitol inhibitor was bound to the M1 site in GI. Thus, these findings provided important information for elucidation or engineering of GI functions. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Case Study: Utilizing a Low FODMAP Diet to Combat Exercise-Induced Gastrointestinal Symptoms.

    PubMed

    Lis, Dana; Ahuja, Kiran D K; Stellingwerff, Trent; Kitic, Cecilia M; Fell, James

    2016-10-01

    Athletes employ various dietary strategies in attempts to attenuate exercise-induced gastrointestinal (GI) symptoms to ensure optimal performance. This case-study outlines one of these GI-targeted approaches via the implementation of a short-term low FODMAP (Fermentable Oligosaccharides, Disaccharides, Monosaccharides and Polyols) diet, with the aim to attenuate persistent running specific GI symptoms in a recreationally competitive multisport athlete (male, 86 kg, 57.9 ml·kg·min -1 V0 2max , 10-15 hr/week training, with no diagnosed GI disorder). Using a single-blinded approach a habitual diet was compared with a 6-day low FODMAP intervention diet (81 ± 5g vs 7.2 ± 5.7g FODMAP s/day) for their effect on GI symptoms and perceptual wellbeing. Training was similar during the habitual and dietary intervention periods. Postexercise (During) GI symptom ratings were recorded immediately following training. Daily GI symptoms and the Daily Analysis of Life Demands for Athletes (DALDA) were recorded at the end of each day. Daily and During GI symptom scores (scale 0-9) ranged from 0-4 during the habitual dietary period while during the low FODMAP dietary period all scores were 0 (no symptoms at all). DALDA scores for worse than normal ranged from 3-10 vs 0-8 in the habitual and low FODMAP dietary periods, respectively, indicating improvement. This intervention was effective for this GI symptom prone athlete; however, randomized-controlled trials are required to assess the suitability of low FODMAP diets for reducing GI distress in other symptomatic athletes.

  11. Taxonomic and functional metagenomic profiling of gastrointestinal tract microbiome of the farmed adult turbot (Scophthalmus maximus).

    PubMed

    Xing, Mengxin; Hou, Zhanhui; Yuan, Jianbo; Liu, Yuan; Qu, Yanmei; Liu, Bin

    2013-12-01

    Metagenomics combined with 16S rRNA gene sequence analyses was applied to unveil the taxonomic composition and functional diversity of the farmed adult turbot gastrointestinal (GI) microbiome. Proteobacteria and Firmicutes which existed in both GI content and mucus were dominated in the turbot GI microbiome. 16S rRNA gene sequence analyses also indicated that the turbot GI tract may harbor some bacteria which originated from associated seawater. Functional analyses indicated that the clustering-based subsystem and many metabolic subsystems were dominant in the turbot GI metagenome. Compared with other gut metagenomes, quorum sensing and biofilm formation was overabundant in the turbot GI metagenome. Genes associated with quorum sensing and biofilm formation were found in species within Vibrio, including Vibrio vulnificus, Vibrio cholerae and Vibrio parahaemolyticus. In farmed fish gut metagenomes, the stress response and protein folding subsystems were over-represented and several genes concerning antibiotic and heavy metal resistance were also detected. These data suggested that the turbot GI microbiome may be affected by human factors in aquaculture. Additionally, iron acquisition and the metabolism subsystem were more abundant in the turbot GI metagenome when compared with freshwater fish gut metagenome, suggesting that unique metabolic potential may be observed in marine animal GI microbiomes. © 2013 Federation of European Microbiological Societies. Published by John Wiley & Sons Ltd. All rights reserved.

  12. Lobular Metastatic Breast Cancer Patients With Gastrointestinal Involvement: Features and Outcomes.

    PubMed

    Montagna, Emilia; Pirola, Sara; Maisonneuve, Patrick; De Roberto, Giuseppe; Cancello, Giuseppe; Palazzo, Antonella; Viale, Giuseppe; Colleoni, Marco

    2017-07-10

    Metastatic breast cancer typically involves the lungs, bones, brain, and liver and only occasionally affects the gastrointestinal (GI) tract. The relevant published data have been limited to case reports and small series of patients. The present study focused on the treatment and outcomes of breast cancer patients with GI involvement diagnosed at the European Institute of Oncology. We analyzed the clinicopathologic features of the GI metastases and compared them with those of the primary tumors according to their histologic type (ductal or lobular carcinoma). From the database of the Department of Pathology, 40 patients who had undergone endoscopy or GI surgery with a final diagnosis of metastatic breast cancer from 2000 to 2014 were identified. The greatest proportion of patients (75%) had had primary invasive lobular carcinoma. Of the 40 patients, 82% had hormone receptor-positive disease in the metastatic lesion; 34 patients were candidates for systemic therapy. The median length of observation after GI metastasis was 18 months (range, 0.6-79 months). The overall survival from the diagnosis of GI involvement was 33 months (95% confidence interval, 16.8-38.3 months). Lobular breast carcinoma has a greater propensity to metastasize to the GI tract compared with other breast cancer subtypes. In the presence of GI symptoms, even if nonspecific, the GI tract should be thoroughly studied. Systemic treatment, including hormonal therapy, should be considered. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. Interactions between rewarding lateral hypothalamic and aversive nucleus reticularis gigantocellularis stimulation.

    PubMed

    Diotte, M; Miguelez, M; Miliaressis, E; Bielajew, C

    2000-12-05

    The interaction between rewarding and aversive consequences of brain stimulation were assessed in two studies. In the first, the frequency threshold for 300 ms trains of combined lateral hypothalamic (LH) and nucleus reticularis gigantocellularis (Gi) stimulation, in which each LH pulse was followed 2 ms later by the Gi one, was determined for one month. Compared to the threshold for trains of single LH pulses, combined LH-Gi stimulation initially increased the frequency threshold; however, this effect reversed within one session and was subsequently maintained for the duration of the study. The aversion produced by Gi stimulation, as measured by latency to escape, was abolished following a single session of LH-Gi pairs. In the second study, a subset of animals received both presentations of combined pulses, LH followed by Gi, and the reverse; the interval between pulses was varied from 0.2 to 6.4 ms. The effectiveness of combined stimulation, determined by the ratio of LH frequency thresholds to that of the LH-Gi ranged from 0 to 50% across animals but the individual effectiveness functions within animals did not vary with different intervals. In addition, the order of presentation of pulses was of no consequence. Thus, not only did exposure to LH stimulation appear to obliterate Gi aversion, but the combination of LH and Gi pulses added to the rewarding effect produced by LH stimulation alone.

  14. Special Report - Post 9/11 GI Bill

    Science.gov Websites

    For the first time in history, servicemembers enrolled in the Post-9/11 GI Bill program will be able , see the Dept. of Veteran's Affairs Web site. Top Stories Officials Tout Post-9/11 GI Bill Benefits this fall under the Post-9/11 GI Bill, officials are continuing an active outreach effort to ensure

  15. Gastrointestinal manifestations of mitochondrial disorders: a systematic review

    PubMed Central

    Finsterer, Josef; Frank, Marlies

    2016-01-01

    Mitochondrial disorders (MIDs) due to respiratory-chain defects or nonrespiratory chain defects are usually multisystem conditions [mitochondrial multiorgan disorder syndrome (MIMODS)] affecting the central nervous system (CNS), peripheral nervous system, eyes, ears, endocrine organs, heart, kidneys, bone marrow, lungs, arteries, and also the intestinal tract. Frequent gastrointestinal (GI) manifestations of MIDs include poor appetite, gastroesophageal sphincter dysfunction, constipation, dysphagia, vomiting, gastroparesis, GI pseudo-obstruction, diarrhea, or pancreatitis and hepatopathy. Rare GI manifestations of MIDs include dry mouth, paradontosis, tracheoesophageal fistula, stenosis of the duodeno-jejunal junction, atresia or imperforate anus, liver cysts, pancreas lipomatosis, pancreatic cysts, congenital stenosis or obstruction of the GI tract, recurrent bowel perforations with intra-abdominal abscesses, postprandial abdominal pain, diverticulosis, or pneumatosis coli. Diagnosing GI involvement in MIDs is not at variance from diagnosing GI disorders due to other causes. Treatment of mitochondrial GI disease includes noninvasive or invasive measures. Therapy is usually symptomatic. Only for myo-neuro-gastro-intestinal encephalopathy is a causal therapy with autologous stem-cell transplantation available. It is concluded that GI manifestations of MIDs are more widespread than so far anticipated and that they must be recognized as early as possible to initiate appropriate diagnostic work-up and avoid any mitochondrion-toxic treatment. PMID:28286566

  16. Effect of Glycemic Index of Breakfast on Energy Intake at Subsequent Meal among Healthy People: A Meta-Analysis

    PubMed Central

    Sun, Feng-Hua; Li, Chunxiao; Zhang, Yan-Jie; Wong, Stephen Heung-Sang; Wang, Lin

    2016-01-01

    Meals with low glycemic index (GI) may suppress short-term appetite and reduce subsequent food intake compared with high-GI meals. However, no meta-analysis has been conducted to synthesize the evidence. This meta-analytic study was conducted to assess the effect of high- and low-GI breakfast on subsequent short-term food intake. Trials were identified through MEDLINE, EMBASE, Web of Science, and Cochrane Central Register of Controlled trials, and manual searches of bibliographies until May 2015. Randomized controlled and cross-over trials comparing the effect of low- with high-GI breakfast on subsequent energy intake among healthy people were included. Nine studies consisting of 11 trials met the inclusion criteria. Only one trial was classified with high methodological quality. A total of 183 participants were involved in the trials. The meta-analytic results revealed no difference in breakfast GI (high-GI vs. low-GI) on subsequent short-term energy intake. In conclusion, it seems that breakfast GI has no effect on short-term energy intake among healthy people. However, high quality studies are still warranted to provide more concrete evidence. PMID:26742058

  17. Carbohydrate-rich foods: glycaemic indices and the effect of constituent macronutrients.

    PubMed

    Widanagamage, Rahal D; Ekanayake, Sagarika; Welihinda, Jayantha

    2009-01-01

    The glycaemic index (GI) ranks foods according to their acute glycaemic impact and is used in planning meals for patients invoking glycaemic control through diet. Kurakkan (Eleusine coracana) flour roti, rice flour roti, atta flour roti, boiled breadfruit (Artocarpus altilis/Artocarpus communis) and boiled legumes (mungbean, cowpea and chickpea) were categorized as low-GI foods (relative to white bread; Prima Crust Top), and the corresponding GI (+/- standard error of the mean) values were 70+/-8, 69+/-7, 67+/-9, 64+/-7, 57+/-6, 49+/-8 and 29+/-5, respectively. Kurakkan flour pittu and wheat flour roti were classified as medium-GI foods with GI values of 85+/-6 and 72+/-6. Hoppers, rice flour pittu, wheat flour pittu and Olu-milk rice (seeds of Nymphaea lotus) were categorized as high-GI foods, and the corresponding GI (+/- standard error of the mean) values were 120+/-8, 103+/-7, 101+/-8 and 91+/-8, respectively. The GI values significantly (P<0.01) and negatively correlated with the insoluble dietary fibre (rho = - 0.780), soluble dietary fibre (rho = - 0.712) and protein (rho = - 0.738) contents in grams per 100 g digestible starch containing foods.

  18. Positive-negative corresponding normalized ghost imaging based on an adaptive threshold

    NASA Astrophysics Data System (ADS)

    Li, G. L.; Zhao, Y.; Yang, Z. H.; Liu, X.

    2016-11-01

    Ghost imaging (GI) technology has attracted increasing attention as a new imaging technique in recent years. However, the signal-to-noise ratio (SNR) of GI with pseudo-thermal light needs to be improved before it meets engineering application demands. We therefore propose a new scheme called positive-negative correspondence normalized GI based on an adaptive threshold (PCNGI-AT) to achieve a good performance with less amount of data. In this work, we use both the advantages of normalized GI (NGI) and positive-negative correspondence GI (P-NCGI). The correctness and feasibility of the scheme were proved in theory before we designed an adaptive threshold selection method, in which the parameter of object signal selection conditions is replaced by the normalizing value. The simulation and experimental results reveal that the SNR of the proposed scheme is better than that of time-correspondence differential GI (TCDGI), avoiding the calculation of the matrix of correlation and reducing the amount of data used. The method proposed will make GI far more practical in engineering applications.

  19. Specialty Engineering Supplement to IEEE-15288.1

    DTIC Science & Technology

    2015-05-15

    receiver required to work in a dense EMI environment. (15) Any RF receiver with a burnout level of less than 30 dBm (1 mW). b. A summary of all...Context 2.1 ISO-IEC-IEEE-15288: 2015, Systems and Software Engineering — System life cycle processes ISO-IEC-IEEE 15288 is the DOD-adopted standard for...to ISO-15288 for application of systems engineering on defense programs that was developed by a joint services working group under the auspices of the

  20. Radar Methods in Urban Environments

    DTIC Science & Technology

    2016-10-26

    to appear in IEEE Journal of Selected Topics in Signal Processing. J8. M. Wang and A. Nehorai, “Coarrays, MUSIC , and the Cramér Rao bound,” to...Journal Papers: 1. P. Chavali and A. Nehorai, "Scheduling and resource allocation in a cognitive radar network for multiple- target tracking,’’ IEEE...Processing. 33. M. Wang and A. Nehorai, "Coarrays, MUSIC , and the Cramér Rao bound," to appear in IEEE Trans. on Signal Processing. 34. J. Li and A. Nehorai

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