Globally Competitive People: Final Report to the Human Resource Committee.

ERIC Educational Resources Information Center

Pennington, Hilary; Austin, John

A globally competitive Mississippi must be built through investment in the education, training, and skills of its people. Recommendations for improving the system involve (1) a human resource and economic development strategy built on a partnership between the state and communities and (2) a state-level human capital strategy board. Critical…

77 FR 61419 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-09

... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special, Emphasis Panel, Global Health. Date: October 29... Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room...

Teaching for Global Perspective: A Resource Handbook.

ERIC Educational Resources Information Center

Roach, Patricia Betts, Ed.

This state resource guide of approximately 250 lesson units for teaching global studies provides 18 topics and from 3-12 lessons for each topic. The topics include global perspective, using models, balance of power, conflict, development, global environment, global resources, global trade, human rights, hunger, ideologies, international…

Think Locally, Act Globally! Linking Local and Global Communities through Democracy and Environment. Hands-On! Developing Active Learning Modules on the Human Dimensions of Global Change.

ERIC Educational Resources Information Center

Dowler, Lorraine

Designed so that it can be adapted to a wide range of student abilities and institutional settings, this learning module on the human dimensions of global change seeks to: actively engage students in problem solving, challenge them to think critically, invite them to participate in the process of scientific inquiry, and involve them in cooperative…

75 FR 51827 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-23

... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...: National Institute of Child Health and Human Development Special Emphasis Panel; Global Data Center for... Human Development, NIH, 6100 Executive Blvd., Room 5B01, Bethesda, MD 20892-9304, 301-435-6680, skandasa...

Global Knowledge Transfer Issues. Symposium 12. [AHRD Conference, 2001].

ERIC Educational Resources Information Center

2001

This document contains three papers on global knowledge transfer issues and human resource development (HRD). "Indigenizing Knowledge Transfer" (Gary N. McLean) explores examples of HRD in which ethnocentric perspectives predominate and argues that, unless a HRD develops a global perspective, efforts to transfer knowledge within academia…

Climate change: The necessary, the possible and the desirable Earth League climate statement on the implications for climate policy from the 5th IPCC Assessment

NASA Astrophysics Data System (ADS)

Rockström, Johan; Brasseur, Guy; Hoskins, Brian; Lucht, Wolfgang; Schellnhuber, John; Kabat, Pavel; Nakicenovic, Nebojsa; Gong, Peng; Schlosser, Peter; Máñez Costa, Maria; Humble, April; Eyre, Nick; Gleick, Peter; James, Rachel; Lucena, Andre; Masera, Omar; Moench, Marcus; Schaeffer, Roberto; Seitzinger, Sybil; van der Leeuw, Sander; Ward, Bob; Stern, Nicholas; Hurrell, James; Srivastava, Leena; Morgan, Jennifer; Nobre, Carlos; Sokona, Youba; Cremades, Roger; Roth, Ellinor; Liverman, Diana; Arnott, James

2014-12-01

The development of human civilisations has occurred at a time of stable climate. This climate stability is now threatened by human activity. The rising global climate risk occurs at a decisive moment for world development. World nations are currently discussing a global development agenda consequent to the Millennium Development Goals (MDGs), which ends in 2015. It is increasingly possible to envisage a world where absolute poverty is largely eradicated within one generation and where ambitious goals on universal access and equal opportunities for dignified lives are adopted. These grand aspirations for a world population approaching or even exceeding nine billion in 2050 is threatened by substantial global environmental risks and by rising inequality. Research shows that development gains, in both rich and poor nations, can be undermined by social, economic and ecological problems caused by human-induced global environmental change. Climate risks, and associated changes in marine and terrestrial ecosystems that regulate the resilience of the climate system, are at the forefront of these global risks. We, as citizens with a strong engagement in Earth system science and socio-ecological dynamics, share the vision of a more equitable and prosperous future for the world, yet we also see threats to this future from shifts in climate and environmental processes. Without collaborative action now, our shared Earth system may not be able to sustainably support a large proportion of humanity in the decades ahead.

Recent Progresses in Incorporating Human Land-Water Management into Global Land Surface Models Toward Their Integration into Earth System Models

NASA Technical Reports Server (NTRS)

Pokhrel, Yadu N.; Hanasaki, Naota; Wada, Yoshihide; Kim, Hyungjun

2016-01-01

The global water cycle has been profoundly affected by human land-water management. As the changes in the water cycle on land can affect the functioning of a wide range of biophysical and biogeochemical processes of the Earth system, it is essential to represent human land-water management in Earth system models (ESMs). During the recent past, noteworthy progress has been made in large-scale modeling of human impacts on the water cycle but sufficient advancements have not yet been made in integrating the newly developed schemes into ESMs. This study reviews the progresses made in incorporating human factors in large-scale hydrological models and their integration into ESMs. The study focuses primarily on the recent advancements and existing challenges in incorporating human impacts in global land surface models (LSMs) as a way forward to the development of ESMs with humans as integral components, but a brief review of global hydrological models (GHMs) is also provided. The study begins with the general overview of human impacts on the water cycle. Then, the algorithms currently employed to represent irrigation, reservoir operation, and groundwater pumping are discussed. Next, methodological deficiencies in current modeling approaches and existing challenges are identified. Furthermore, light is shed on the sources of uncertainties associated with model parameterizations, grid resolution, and datasets used for forcing and validation. Finally, representing human land-water management in LSMs is highlighted as an important research direction toward developing integrated models using ESM frameworks for the holistic study of human-water interactions within the Earths system.

Building "Special Capital" for Entrepreneurial Development: Special Populations as Human Capital in the Context of Global Development

ERIC Educational Resources Information Center

Walker, Gabriela

2010-01-01

Ten to twelve percent of the world population is identified as having one or more types of disability. This ecodeme has been historically known to be discriminated, marginalized, and disempowered by the lack of access to resources and to education. This article discusses the importance of adding special capital to the global human capital in the…

Progress and Challenges in Developing Reference Data Layers for Human Population Distribution and Built Infrastructure

NASA Astrophysics Data System (ADS)

Chen, R. S.; Yetman, G.; de Sherbinin, A. M.

2015-12-01

Understanding the interactions between environmental and human systems, and in particular supporting the applications of Earth science data and knowledge in place-based decision making, requires systematic assessment of the distribution and dynamics of human population and the built human infrastructure in conjunction with environmental variability and change. The NASA Socioeconomic Data and Applications Center (SEDAC) operated by the Center for International Earth Science Information Network (CIESIN) at Columbia University has had a long track record in developing reference data layers for human population and settlements and is expanding its efforts on topics such as intercity roads, reservoirs and dams, and energy infrastructure. SEDAC has set as a strategic priority the acquisition, development, and dissemination of data resources derived from remote sensing and socioeconomic data on urban land use change, including temporally and spatially disaggregated data on urban change and rates of change, the built infrastructure, and critical facilities. We report here on a range of past and ongoing activities, including the Global Human Settlements Layer effort led by the European Commission's Joint Research Centre (JRC), the Global Exposure Database for the Global Earthquake Model (GED4GEM) project, the Global Roads Open Access Data Working Group (gROADS) of the Committee on Data for Science and Technology (CODATA), and recent work with ImageCat, Inc. to improve estimates of the exposure and fragility of buildings, road and rail infrastructure, and other facilities with respect to selected natural hazards. New efforts such as the proposed Global Human Settlement indicators initiative of the Group on Earth Observations (GEO) could help fill critical gaps and link potential reference data layers with user needs. We highlight key sectors and themes that require further attention, and the many significant challenges that remain in developing comprehensive, high quality, up-to-date, and well maintained reference data layers on population and built infrastructure. The need for improved indicators of sustainable development in the context of the post-2015 development framework provides an opportunity to link data efforts directly with international development needs and investments.

The View From Orthodoxy: Point/Counterpoint on Globalization and Human Rights.

PubMed

Schuftan, Claudio

2018-04-01

The long-term trend of globalization masks a frank deterioration of the situation of the have-nots. Since 1970, polarization has grown faster than inequality, with alarming consequences for human rights and the economy overall. Globalization has continued to enrich the few at the expense of providing a decent livelihood and respecting the human rights of the many. Industrialized countries continue to be the rule makers-poor countries the rule takers. Rich countries go for growth, but an inequality-entrenching growth that brings about human rights violations and poverty. In many developing economies, income inequality and the violation of human rights have clearly increased over the past 3 decades. Discriminated losers have been fighting globalization before it had a name; they still are. Globalization has thus actually resulted in greater income inequality plus human rights violations and disrupted lives. Globalization may well be a finished project. We must remind our respective governments that they have the power to improve working people's lives so that they, once and for all, address the needs of those who lose out from technological change and globalization. Otherwise, our political problems will only deepen.

Non-communicable diseases and human rights: Global synergies, gaps and opportunities.

PubMed

Ferguson, Laura; Tarantola, Daniel; Hoffmann, Michael; Gruskin, Sofia

2017-10-01

The incorporation of human rights in health policy and programmes is known to strengthen responses to health problems and help address disparities created or exacerbated by illness yet this remains underexplored in relation to non-communicable diseases (NCDs). Aiming to understand existing synergies and how they might be further strengthened, we assessed the extent to which human rights are considered in global NCD policies and strategies and the degree of attention given to NCDs by select United Nations human rights mechanisms. Across global NCD policies and strategies, rhetorical assertions regarding human rights appear more often than actionable statements, thus limiting their implementation and impact. Although no human rights treaty explicitly mentions NCDs, some human rights monitoring mechanisms have been paying increasing attention to NCDs. This provides important avenues for promoting the incorporation of human rights norms and standards into NCD responses as well as for accountability. Linking NCDs and human rights at the global level is critical for encouraging national-level action to promote better outcomes relating to both health and human rights. The post-2015 development agenda constitutes a key entry point for highlighting these synergies and strengthening opportunities for health and rights action at global, national and local levels.

Global and local processing in adult humans (Homo sapiens), 5-year-old children (Homo sapiens), and adult cotton-top tamarins (Saguinus oedipus).

PubMed

Neiworth, Julie J; Gleichman, Amy J; Olinick, Anne S; Lamp, Kristen E

2006-11-01

This study compared adults (Homo sapiens), young children (Homo sapiens), and adult tamarins (Saguinus oedipus) while they discriminated global and local properties of stimuli. Subjects were trained to discriminate a circle made of circle elements from a square made of square elements and were tested with circles made of squares and squares made of circles. Adult humans showed a global bias in testing that was unaffected by the density of the elements in the stimuli. Children showed a global bias with dense displays but discriminated by both local and global properties with sparse displays. Adult tamarins' biases matched those of the children. The striking similarity between the perceptual processing of adult monkeys and humans diagnosed with autism and the difference between this and normatively developing human perception is discussed.

Educating for an Inclusive World: Lessons Learned from a Globally Networked Human Rights and Disability Course for Social Work and Law Students

ERIC Educational Resources Information Center

Critelli, Filomena; Lewis, Laura; Méndez-López, Adalberto

2017-01-01

This article examines an innovative model of online international education regarding disability through a human rights perspective piloted through a collaboration between Universidad LaSalle, Mexico, and University at Buffalo, United States. The course is organized around a pressing global human rights and development issue. Its objective is to…

The evolution of human rights in World Health Organization policy and the future of human rights through global health governance.

PubMed

Meier, B M; Onzivu, W

2014-02-01

The World Health Organization (WHO) was intended to serve at the forefront of efforts to realize human rights to advance global health, and yet this promise of a rights-based approach to health has long been threatened by political constraints in international relations, organizational resistance to legal discourses, and medical ambivalence toward human rights. Through legal research on international treaty obligations, historical research in the WHO organizational archives, and interview research with global health stakeholders, this research examines WHO's contributions to (and, in many cases, negligence of) the rights-based approach to health. Based upon such research, this article analyzes the evolving role of WHO in the development and implementation of human rights for global health, reviews the current state of human rights leadership in the WHO Secretariat, and looks to future institutions to reclaim the mantle of human rights as a normative framework for global health governance. Copyright © 2013 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

Bridging international law and rights-based litigation: mapping health-related rights through the development of the Global Health and Human Rights Database.

PubMed

Meier, Benjamin Mason; Cabrera, Oscar A; Ayala, Ana; Gostin, Lawrence O

2012-06-15

The O'Neill Institute for National and Global Health Law at Georgetown University, the World Health Organization, and the Lawyers Collective have come together to develop a searchable Global Health and Human Rights Database that maps the intersection of health and human rights in judgments, international and regional instruments, and national constitutions. Where states long remained unaccountable for violations of health-related human rights, litigation has arisen as a central mechanism in an expanding movement to create rights-based accountability. Facilitated by the incorporation of international human rights standards in national law, this judicial enforcement has supported the implementation of rights-based claims, giving meaning to states' longstanding obligations to realize the highest attainable standard of health. Yet despite these advancements, there has been insufficient awareness of the international and domestic legal instruments enshrining health-related rights and little understanding of the scope and content of litigation upholding these rights. As this accountability movement evolves, the Global Health and Human Rights Database seeks to chart this burgeoning landscape of international instruments, national constitutions, and judgments for health-related rights. Employing international legal research to document and catalogue these three interconnected aspects of human rights for the public's health, the Database's categorization by human rights, health topics, and regional scope provides a comprehensive means of understanding health and human rights law. Through these categorizations, the Global Health and Human Rights Database serves as a basis for analogous legal reasoning across states to serve as precedents for future cases, for comparative legal analysis of similar health claims in different country contexts, and for empirical research to clarify the impact of human rights judgments on public health outcomes. Copyright © 2012 Meier, Nygren-Krug, Cabrera, Ayala, and Gostin.

Global health justice and governance.

PubMed

Ruger, Jennifer Prah

2012-01-01

While there is a growing body of work on moral issues and global governance in the fields of global justice and international relations, little work has connected principles of global health justice with those of global health governance for a theory of global health. Such a theory would enable analysis and evaluation of the current global health system and would ethically and empirically ground proposals for reforming it to more closely align with moral values. Global health governance has been framed as an issue of national security, human security, human rights, and global public goods. The global health governance literature is essentially untethered to a theorized framework to illuminate or evaluate governance. This article ties global health justice and ethics to principles for governing the global health realm, developing a theoretical framework for global and domestic institutions and actors.

Global Perspectives on Resilience in Children and Youth

ERIC Educational Resources Information Center

Masten, Ann S.

2014-01-01

Global concerns about the consequences of disasters, political violence, disease, malnutrition, maltreatment, and other threats to human development and well-being have sparked a surge of international interest in resilience science. This article highlights progress and issues in research that aims to understand variations in human adaptation to…

Efficient prediction of human protein-protein interactions at a global scale.

PubMed

Schoenrock, Andrew; Samanfar, Bahram; Pitre, Sylvain; Hooshyar, Mohsen; Jin, Ke; Phillips, Charles A; Wang, Hui; Phanse, Sadhna; Omidi, Katayoun; Gui, Yuan; Alamgir, Md; Wong, Alex; Barrenäs, Fredrik; Babu, Mohan; Benson, Mikael; Langston, Michael A; Green, James R; Dehne, Frank; Golshani, Ashkan

2014-12-10

Our knowledge of global protein-protein interaction (PPI) networks in complex organisms such as humans is hindered by technical limitations of current methods. On the basis of short co-occurring polypeptide regions, we developed a tool called MP-PIPE capable of predicting a global human PPI network within 3 months. With a recall of 23% at a precision of 82.1%, we predicted 172,132 putative PPIs. We demonstrate the usefulness of these predictions through a range of experiments. The speed and accuracy associated with MP-PIPE can make this a potential tool to study individual human PPI networks (from genomic sequences alone) for personalized medicine.

Global health governance in the sustainable development goals: Is it grounded in the right to health?

PubMed

Van de Pas, Remco; Hill, Peter S; Hammonds, Rachel; Ooms, Gorik; Forman, Lisa; Waris, Attiya; Brolan, Claire E; McKee, Martin; Sridhar, Devi

2017-01-01

This paper explores the extent to which global health governance - in the context of the early implementation of the Sustainable Development Goals is grounded in the right to health. The essential components of the right to health in relation to global health are unpacked. Four essential functions of the global health system are assessed from a normative, rights-based, analysis on how each of these governance functions should operate. These essential functions are: the production of global public goods, the management of externalities across countries, the mobilization of global solidarity, and stewardship. The paper maps the current reality of global health governance now that the post-2015 Sustainable Development Goals are beginning to be implemented. In theory, the existing human rights legislation would enable the principles and basis for the global governance of health beyond the premise of the state. In practice, there is a governance gap between the human rights framework and practices in global health and development policies. This gap can be explained by the political determinants of health that shape the governance of these global policies. Current representations of the right to health in the Sustainable Development Goals are insufficient and superficial, because they do not explicitly link commitments or right to health discourse to binding treaty obligations for duty-bearing nation states or entitlements by people. If global health policy is to meaningfully contribute to the realization of the right to health and to rights based global health governance then future iterations of global health policy must bridge this gap. This includes scholarship and policy debate on the structure, politics, and agency to overcome existing global health injustices.

Global health governance in the sustainable development goals: Is it grounded in the right to health?

PubMed Central

Hill, Peter S.; Hammonds, Rachel; Ooms, Gorik; Forman, Lisa; Waris, Attiya; Brolan, Claire E.; McKee, Martin; Sridhar, Devi

2017-01-01

Abstract This paper explores the extent to which global health governance – in the context of the early implementation of the Sustainable Development Goals is grounded in the right to health. The essential components of the right to health in relation to global health are unpacked. Four essential functions of the global health system are assessed from a normative, rights‐based, analysis on how each of these governance functions should operate. These essential functions are: the production of global public goods, the management of externalities across countries, the mobilization of global solidarity, and stewardship. The paper maps the current reality of global health governance now that the post‐2015 Sustainable Development Goals are beginning to be implemented. In theory, the existing human rights legislation would enable the principles and basis for the global governance of health beyond the premise of the state. In practice, there is a governance gap between the human rights framework and practices in global health and development policies. This gap can be explained by the political determinants of health that shape the governance of these global policies. Current representations of the right to health in the Sustainable Development Goals are insufficient and superficial, because they do not explicitly link commitments or right to health discourse to binding treaty obligations for duty‐bearing nation states or entitlements by people. If global health policy is to meaningfully contribute to the realization of the right to health and to rights based global health governance then future iterations of global health policy must bridge this gap. This includes scholarship and policy debate on the structure, politics, and agency to overcome existing global health injustices. PMID:28616255

Globalizing Agricultural Science and Education Programs for America.

ERIC Educational Resources Information Center

National Association of State Universities and Land Grant Colleges, Washington, DC.

This document proposes an agenda for globalizing agricultural science and education which has implications for higher education, research, and extension programs at land-grant and similar universities. To enhance global competitiveness of U.S. agriculture through human resource development, institutions are urged to: globalize undergraduate and…

Management Development. Symposium 15. [Concurrent Symposium Session at AHRD Annual Conference, 2000.

ERIC Educational Resources Information Center

2000

Three presentations are provided from Symposium 15, Management Development, of the Academy of Human Resource Development (HRD) 2000 Conference Proceedings. "Conceptualizing Global Leadership from Multiple Perspectives: An Analysis of Behavioral Ratings" (Allan H. Church) examines the underlying nature of global leadership behavior using…

Implications of global climate change for housing, human settlements and public health.

PubMed

Hales, Simon; Baker, Michael; Howden-Chapman, Philippa; Menne, Bettina; Woodruff, Rosalie; Woodward, Alistair

2007-01-01

Global climate change has profound implications for human societies. The present---ecologically unsustainable--trajectory of human development fails to provide for the basic needs of a substantial fraction of the global population, while diminishing the prospects for future generations. Human-caused climate change has already begun to affect weather patterns, physical and biological phenomena, and vulnerable human communities. Because the social processes of production and consumption have their own momentum, and because carbon dioxide has a long atmospheric lifetime, further climate change is inevitable over the coming century, even allowing for the adoption of mitigation measures. This situation implies that we should also try to reduce, and where possible to prevent, the adverse effects of climate changes by planned adaptation. Will human settlements be able to provide a healthy living environment and shelter from extreme climate events, such as cyclones and heat waves? In this paper, we review the nexus between human health, climate change, and the planning of housing and human settlements. We conclude that adapting to a rapidly changing global environment will be a major challenge, in the context of increasing population and per capita consumption, without increasing pressures on natural systems. Energy-efficient cities and the creation of opportunities for poor countries will be important elements of people centered, ecologically sustainable, development in the twenty-first century.

Population Growth, Energy Use, and Pollution: Understanding the Driving Forces of Global Change. Hands-On! Developing Active Learning Modules on the Human Dimensions of Global Change.

ERIC Educational Resources Information Center

Kuby, Michael

Since the beginning of the scientific revolution in the 1700s, the absolute scale of the human economy has increased many times over, and, with it, the impact on the natural environment. This learning module's activities introduce the student to linkages among population growth, energy use, level of economic and technological development and their…

Pathways of Understanding: the Interactions of Humanity and Global Environmental Change

NASA Technical Reports Server (NTRS)

Jacobson, Harold K.; Katzenberger, John; Lousma, Jack; Mooney, Harold A.; Moss, Richard H.; Kuhn, William; Luterbacher, Urs; Wiegandt, Ellen

1992-01-01

How humans, interacting within social systems, affect and are affected by global change is explored. Recognizing the impact human activities have on the environment and responding to the need to document the interactions among human activities, the Consortium for International Earth Science Information Network (CIESIN) commissioned a group of 12 scientists to develop a framework illustrating the key human systems that contribute to global change. This framework, called the Social Process Diagram, will help natural and social scientists, educators, resource managers and policy makers envision and analyze how human systems interact among themselves and with the natural system. The Social Process Diagram consists of the following blocks that constitute the Diagram's structural framework: (1) fund of knowledge and experience; (2) preferences and expectations; (3) factors of production and technology; (4) population and social structure; (5) economic systems; (6) political systems and institutions; and (7) global scale environmental processes. To demonstrate potential ways the Diagram can be used, this document includes 3 hypothetical scenarios of global change issues: global warming and sea level rise; the environmental impact of human population migration; and energy and the environment. These scenarios demonstrate the Diagram's usefulness for visualizing specific processes that might be studied to evaluate a particular global change issues. The scenario also shows that interesting and unanticipated questions may emerge as links are explored between categories on the Diagram.

Human impacts on 20th century fire dynamics and implications for global carbon and water trajectories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Fang; Lawrence, David M.; Bond-Lamberty, Ben

Fire is a fundamental Earth system process and the primary ecosystem disturbance on the global scale. It affects carbon and water cycles through changing terrestrial ecosystems, and at the same time, is regulated by weather and climate, vegetation characteristics, and, importantly, human ignitions and suppression (i.e., the direct human effect on fire). Here, we utilize the Community Land Model version 4.5 (CLM4.5) to quantify the impacts of changes in human ignition and suppression on fire dynamics and associated carbon and water cycles. We find that the impact is to significantly reduce the 20th century global burned area by a centurymore » average of 38 Mha/yr and by 103 Mha/yr at the end of the century. Land carbon gain is weakened by 17% over the 20th century, mainly due to increased human deforestation fires and associated escape fires (i.e., degradation fires) in the tropical humid forests, even though the decrease in burned area in many other regions due to human fire suppression acts to increase land carbon gain. The direct human effect on fire weakens the upward trend in global runoff throughout the century by 6% and enhances the upward trend in global evapotranspiration since ~ 1945 by 7%. In addition, the above impacts in densely populated, highly developed (if population density > 0.1 person/km2), or moderately populated and developed regions are of opposite sign to those in other regions. Our study suggests that particular attention should be paid to human deforestation and degradation fires in the tropical humid forests when reconstructing and projecting fire carbon emissions and net atmosphere-land carbon exchange and estimating resultant impacts of direct human effect on fire.« less

Human impacts on 20th century fire dynamics and implications for global carbon and water trajectories

NASA Astrophysics Data System (ADS)

Li, Fang; Lawrence, David M.; Bond-Lamberty, Ben

2018-03-01

Fire is a fundamental Earth system process and the primary ecosystem disturbance on the global scale. It affects carbon and water cycles through changing terrestrial ecosystems, and at the same time, is regulated by weather and climate, vegetation characteristics, and, importantly, human ignitions and suppression (i.e., the direct human effect on fire). Here, we utilize the Community Land Model version 4.5 (CLM4.5) to quantify the impacts of changes in human ignition and suppression on fire dynamics and associated carbon and water cycles. We find that the impact is to significantly reduce the 20th century global burned area by a century average of 38 Mha/yr and by 103 Mha/yr at the end of the century. Land carbon gain is weakened by 17% over the 20th century, mainly due to increased human deforestation fires and associated escape fires (i.e., degradation fires) in the tropical humid forests, even though the decrease in burned area in many other regions due to human fire suppression acts to increase land carbon gain. The direct human effect on fire weakens the upward trend in global runoff throughout the century by 6% and enhances the upward trend in global evapotranspiration since 1945 by 7%. In addition, the above impacts in densely populated, highly developed (if population density > 0.1 person/km2), or moderately populated and developed regions are of opposite sign to those in other regions. Our study suggests that particular attention should be paid to human deforestation and degradation fires in the tropical humid forests when reconstructing and projecting fire carbon emissions and net atmosphere-land carbon exchange and estimating resultant impacts of direct human effect on fire.

Teaching global and local environmental change through Remote Sensing

NASA Astrophysics Data System (ADS)

Mauri, Emanuela Paola; Rossi, Giovanni

2013-04-01

Human beings perceive the world primarily through their sense of sight. This can explain why the use of images is so important and common in educational materials, in particular for scientific subjects. The development of modern technologies for visualizing the scientific features of the Earth has provided new opportunities for communicating the increasing complexity of science both to the public and in school education. In particular, the use of Earth observation satellites for civil purposes, which started in the 70s, has opened new perspectives in the study of natural phenomena and human impact on the environment; this is particularly relevant for those processes developing on a long term period and on a global scale. Instruments for Remote Sensing increase the power of human sight, giving access to additional information about the physical world, which the human eye could not otherwise perceive. The possibility to observe from a remote perspective significant processes like climate change, ozone depletion, desertification, urban development, makes it possible for observers to better appreciate and experience the complexity of environment. Remote Sensing reveals the impact of human activities on ecosystems: this allows students to understand important concepts like global and local change in much more depth. This poster describes the role and effectiveness of Remote Sensing imagery in scientific education, and its importance towards a better global environmental awareness.

Salutogenesis, globalization, and communication.

PubMed

Petzold, Theodor Dierk; Lehmann, Nadja

2011-12-01

Achieving successful communication in transcultural contexts means integrating emotional communication patterns into a global context. Professional, rational communication is characteristic of the cultural dimension, and emotions are characteristic of the direct, interpersonal dimension of human existence. Humans strive to achieve coherence in all dimensions of their lives; this goal is in the end the most essential aspect of psychophysical self-regulation. A major role in integrating emotional needs and cultural features in global coherence is played by the attractor 'global affinity'. The transitions from emotional coherence to cultural coherence, and likewise from cultural coherence to global coherence, can cause considerable insecurity as well as psychological problems, which previously went by the name 'adjustment disorders'. However, instead of pathologizing these processes, we should understand them in a salutogenic sense as challenges important for both individual and collective development. The development of more coherence is regulated by the neuropsychological approach and avoidance system. This system can be consciously fostered by directing our attention to the commonalities of all human beings. Such a global salutogenic orientation furthers both communication and creativity in teamwork. This article introduces a consequent salutogenic and evolutionary systemic view of transcultural communication and demonstrates its effectiveness in a number of case examples.

Towards the Development of a Cultural Competence Framework for Human Resource Development Professionals in International Business: A Study of Best Practice Learning and Diversity Companies

ERIC Educational Resources Information Center

Kyeyune, Catherine

2012-01-01

In a global environment, growing business corporations have recognized the role diversity plays in business development. However, the human resource development (HRD) profession charged with the responsibility for developing any organization's human resources, has not defined what cultural competence is and its role in improving the…

Coastal sedimentary research examines critical issues of national and global priority

USGS Publications Warehouse

Fletcher, Chip; Anderson, John; Crook, Keith A.W.; Kaminsky, George; Larcombe, Piers; Murray-Wallace, Colin V.; Sansone, Frank; Scott, David B.; Riggs, Stan; Sallenger, Asbury; Shennan, Ian; Thieler, E. Robert; Wehmiller, John F.

2000-01-01

An international conference was held recently in Honolulu, Hawaii, to examine and plan for coastal sedimentary research in the United States and globally. Participants agreed that sedimentary coastal environments constitute a critical national and global resource that suffers widespread degradation due to human impacts. Moreover, human population growth and inappropriate development in the coastal zone are escalating public asset losses due to coastal hazards and placing large numbers of communities at growing risk (Figure 1).

The quadruple squeeze: defining the safe operating space for freshwater use to achieve a triply green revolution in the anthropocene.

PubMed

Rockström, Johan; Karlberg, Louise

2010-05-01

Humanity has entered a new phase of sustainability challenges, the Anthropocene, in which human development has reached a scale where it affects vital planetary processes. Under the pressure from a quadruple squeeze-from population and development pressures, the anthropogenic climate crisis, the anthropogenic ecosystem crisis, and the risk of deleterious tipping points in the Earth system-the degrees of freedom for sustainable human exploitation of planet Earth are severely restrained. It is in this reality that a new green revolution in world food production needs to occur, to attain food security and human development over the coming decades. Global freshwater resources are, and will increasingly be, a fundamental limiting factor in feeding the world. Current water vulnerabilities in the regions in most need of large agricultural productivity improvements are projected to increase under the pressure from global environmental change. The sustainability challenge for world agriculture has to be set within the new global sustainability context. We present new proposed sustainability criteria for world agriculture, where world food production systems are transformed in order to allow humanity to stay within the safe operating space of planetary boundaries. In order to secure global resilience and thereby raise the chances of planet Earth to remain in the current desired state, conducive for human development on the long-term, these planetary boundaries need to be respected. This calls for a triply green revolution, which not only more than doubles food production in many regions of the world, but which also is environmentally sustainable, and invests in the untapped opportunities to use green water in rainfed agriculture as a key source of future productivity enhancement. To achieve such a global transformation of agriculture, there is a need for more innovative options for water interventions at the landscape scale, accounting for both green and blue water, as well as a new focus on cross-scale interactions, feed-backs and risks for unwanted regime shifts in the agro-ecological landscape.

Education, Human Development and Quality of Life: Measurement Issues and Implications for India

ERIC Educational Resources Information Center

Narayana, M. R.

2009-01-01

This paper analyses and compares the measurement of indicators and variables in the construction of education index in Human Development Index (HDI) at the global, national and 18 sub-national human development reports in India since 1990. The results show non-comparability of measurement of the education indicators and variables. This implies…

Preparing Globally Competent Teacher Candidates through Cross-Cultural Experiential Learning

ERIC Educational Resources Information Center

Kopish, Michael A.

2016-01-01

This manuscript presents findings and implications from a case study of one global educator's attempt to develop globally competent teacher candidates in an elective teacher preparation course. Global Citizenship Education served as the framing paradigm for the course and human experiences of immigrants and refugees served as the milieu for…

Open Earth Observation Data for Measuring Anthropogenic Development in Coastal Zones at Continental Scales

NASA Astrophysics Data System (ADS)

Du, X.; Leinenkugel, P.; Guo, H.; Kuenzer, C.

2017-12-01

During the recent decades, global coasts are undergoing tremendous change due to accelerating socio-economic growth, which has severe effects on the functioning of global coastal systems. In view of this, accurate, timely, and area-wide global information on natural as well as anthropogenic processes in the coastal zone are of paramount importance for sustainable coastal development. A broad range of freely available satellite derived products, and open geo-datasets, as well as statistics with global coverage exist that have not yet been fully exploited to evaluate human development patterns in coastal areas. In this study, we demonstrate the potential of freely and openly available EO and GEO data sets for characterizing and evaluating human development in coastal zones on large scales. Therefore, different geo-spatial dataset such as Global Urban Footprint (GUF), Open Street Map (OSM), time series of Global Human Settlement Layer (GHSL) and Climate Change Initiative (CCI) Land cover were acquired for the entire continental coast of Asia, defined as the terrestrial area 100 km from the coastline. In order to extract indices for the coastline, a reference structure was developed allowing the integration of a 2D spatial pattern of a given parameter to a certain location along the coast line. Based on this reference structure statistics for the coast were calculated every 5 km parallel to the coast line as well as for four different distance intervals from the coast. The results demonstrate the highly unequal distribution of coastal development with respect to urban and agricultural usage in Asia, with large differences between and within different countries. China coasts show the highest overall patterns of urban development, while countries such as Pakistan and Myanmar show comparably low levels with nearly no development evident absence from coastal metropolitan areas. Furthermore, a clear trend of decreasing urban development is evident with increasing distance from the coast. This study highlights the potential of global geo-spatial data products for deriving anthropogenic development indicators that can support the evaluation and monitoring for sustainable development of coastal zones, while also discussing the shortcomings of these datasets for such purposes.

Internationalizing the Right to Know: Conceptualizations of Access to Information in Human Rights Law

ERIC Educational Resources Information Center

Bishop, Cheryl Ann

2009-01-01

Currently there exists a global movement promoting institutional transparency and freedom of information legislation. Conceptualizing access to government-held information as a human right is one of the latest developments in this global trend promoting access to information. The purpose of this dissertation is to identify and analyze the various…

The Asian Human Resource Approach in Global Perspective.

ERIC Educational Resources Information Center

Cummings, William K.

1995-01-01

Challenges the prevailing Western approach to education by asserting that several Asian nations have and are developing a distinctive approach to human resource development. Describes characteristics of this approach and contrasts it to the Western model. (CFR)

Globalization, culture and psychology.

PubMed

Melluish, Steve

2014-10-01

This article outlines the cultural and psychological effects of globalization. It looks at the impact of globalization on identity; ideas of privacy and intimacy; the way we understand and perceive psychological distress; and the development of the profession of psychology around the world. The article takes a critical perspective on globalization, seeing it as aligned with the spread of neoliberal capitalism, a tendency towards cultural homogenization, the imposition of dominant 'global north' ideas and the resultant growing inequalities in health and well-being. However, it also argues that the increased interconnectedness created by globalization allows for greater acknowledgement of our common humanity and for collective efforts to be developed to tackle what are increasingly global problems. This requires the development of more nuanced understandings of cultural differences and of indigenous psychologies.

From climate to global change: Following the footprint of Prof. Duzheng YE's research

NASA Astrophysics Data System (ADS)

Fu, Congbin

2017-10-01

To commemorate 100 years since the birth of Professor Duzheng YE, this paper reviews the contribution of Ye and his research team to the development from climate to global change science in the past 30 or so years, including: (1) the role of climate change in global change; (2) the critical time scales and predictability of global change; (3) the sensitive regions of global change—transitional zones of climate and ecosystems; and (4) orderly human activities and adaptation to global change, with a focus on the development of a proactive strategy for adaptation to such change.

Recombinant Human Insulin in Global Diabetes Management – Focus on Clinical Efficacy

PubMed Central

Mbanya, Jean Claude; Sandow, Juergen; Landgraf, Wolfgang

2017-01-01

Abstract Biosynthetic human insulin and insulin analogues are the mainstay of insulin therapy for both type 1 and type 2 diabetes although access to human insulin at affordable prices remains a global issue. The world is experiencing an exponential rise in the prevalence of diabetes presenting an urgent need to establish effective diabetes therapy in countries burdened by inadequate health care budgets, malnutrition and infectious diseases. Recombinant human insulin has replaced animal insulins and animal-based semisynthetic human insulin thereby available in sufficient quantities and at affordable prices able to provide global access to insulin therapy. In many patients, analog insulins can offer additional clinical benefit, although at a considerably higher price thus severely restricting availability in low income countries. The approval process for recombinant human insulins (i.e. biosimilars) and analogue insulins is highly variable in the developing countries in contrast to Europe and in North America, where it is well established within a strict regulatory framework. This review aims to discuss the future access to human insulin therapy in a global context with an ever increasing burden of diabetes and significant economic implications. PMID:29632602

Improving Global Health Education: Development of a Global Health Competency Model

PubMed Central

Ablah, Elizabeth; Biberman, Dorothy A.; Weist, Elizabeth M.; Buekens, Pierre; Bentley, Margaret E.; Burke, Donald; Finnegan, John R.; Flahault, Antoine; Frenk, Julio; Gotsch, Audrey R.; Klag, Michael J.; Lopez, Mario Henry Rodriguez; Nasca, Philip; Shortell, Stephen; Spencer, Harrison C.

2014-01-01

Although global health is a recommended content area for the future of education in public health, no standardized global health competency model existed for master-level public health students. Without such a competency model, academic institutions are challenged to ensure that students are able to demonstrate the knowledge, skills, and attitudes (KSAs) needed for successful performance in today's global health workforce. The Association of Schools of Public Health (ASPH) sought to address this need by facilitating the development of a global health competency model through a multistage modified-Delphi process. Practitioners and academic global health experts provided leadership and guidance throughout the competency development process. The resulting product, the Global Health Competency Model 1.1, includes seven domains and 36 competencies. The Global Health Competency Model 1.1 provides a platform for engaging educators, students, and global health employers in discussion of the KSAs needed to improve human health on a global scale. PMID:24445206

National Security Implications of Global Warming Policy

DTIC Science & Technology

2010-03-01

Although numerous historical examples demonstrate how actual climate change has contributed to the rise and fall of powers, global warming , in and of...become convinced that global warming is universally bad and humans are the primary cause, political leaders may develop ill-advised policies restricting

Social implications of the Human Genome Project: Policy roundtable series and journals. Final progress report, March 15, 2001 - March 15, 2002

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seiguer, Erica

2002-12-30

This report reflects the activities of the Harvard Health Caucus at Harvard Medical School that were supported, in part, by the Department of Energy. The following policy roundtables and panels were held: Spring 2001 Policy Roundtable Series: The social implications of the Human Genome Project; Spring 2002 Policy Roundtable Series: Managing globalization to improve health; 13 February 2002 Keynote Address: The globalization of health; 25 February 2002 Healthier or Wealthier: Which comes first in the new global era?; 28 February 2002 The crisis of neglected diseases: Creating R&D incentives for diseases of developing countries; 7 March 2002 Health care educationmore » in the developing world: Bridging global and local health care practices; 20 March 2002 Building a legal framework for global health: How can the US and UN work to reduce global disparities?; 25 April 2002 The role of mass media and tobacco control efforts. Caucus organizational information is also included.« less

Education Trends, Norms and Development.

ERIC Educational Resources Information Center

Abdel-Magid, Isam Mohammed; Elsadig, Elsadig Hassan

The impact of globalization on vocational-technical education (VTE) and human resource development (HRD) in Sudan was examined. Special attention was paid to the following issues: the purpose of education in the 21st century; learning for the workplace; national culture and technological advances; the globalization of education; education and…

Feeling global, acting ethically: global identification and fairtrade consumption.

PubMed

Reese, Gerhard; Kohlmann, Fabienne

2015-01-01

Global identification has become a popular construct in recent psychological debate as it relates to harmonious intergroup relations and a caring for all humanity. Based on social identity theorizing, the current research tests whether global identification can also predict consumer choices, at the expense of lower personal benefit. Importantly, we assumed that concerns about global injustice represent a crucial component of that relation. We predicted that participants who identified strongly with all humanity would rather choose a Fairtrade product alternative over a conventional one, compared with low identifiers. In addition, we assumed that this effect be mediated by perceived global injustice. Both predictions were confirmed in a consumer choice study (N = 68). Overall, global identification and globally relevant consumer behavior seem meaningfully interconnected, and we discuss these findings with regard to recent theoretical developments in Fairtrade consumption research.

Comparative Analysis of OECD Member Countries' Competitive Advantage in National Human Resource Development System

ERIC Educational Resources Information Center

Oh, Hunseok; Choi, Yeseul; Choi, Myungweon

2013-01-01

The purpose of this study was to assess, evaluate, and compare the competitive advantages of the human resource development systems of advanced countries. The Global Human Resource Development Index was utilized for this study, since it has been validated through an expert panel's content review and analytic hierarchy process. Using a sample of 34…

Global bioethics and communitarianism.

PubMed

ten Have, Henk A M J

2011-10-01

This paper explores the role of 'community' in the context of global bioethics. With the present globalization of bioethics, new and interesting references are made to this concept. Some are familiar, for example, community consent. This article argues that the principle of informed consent is too individual-oriented and that in other cultures, consent can be community-based. Other references to 'community' are related to the novel principle of benefit sharing in the context of bioprospecting. The application of this principle necessarily requires the identification and construction of communities. On the global level there are also new uses of the concept of community as 'global community.' Three uses are distinguished: (1) a diachronic use, including past, present, and future generations, (2) a synchronic ecological use, including nonhuman species, and (3) a synchronic planetary use, including all human beings worldwide. Although there is a tension between the communitarian perspective and the idea of global community, this article argues that the third use can broaden communitarianism. The current development towards cosmopolitanism is creating a new global community that represents humanity as a whole, enabling identification of world citizens and evoking a sense of global solidarity and responsibility. The emergence of global bioethics today demonstrates this development.

Challenges of Global Change for Lakes

NASA Astrophysics Data System (ADS)

Seekell, D.

2016-12-01

Lakes comprise a tiny fraction of Earth's surface, but contribute significantly to human life and wellbeing. Many lakes are disappearing due to climate change and water diversions, and there are widespread disruptions to ecosystem processes due to human influences. For example, pollution by nutrients and toxic chemicals causes toxicity to humans, livestock, fish, and wildlife. Lake desiccation reduces economic opportunity and food security, displacing entire communities. Understanding these changes at the global scale, and their implications for human societies, are a key challenges for aquatic scientists. In this talk, I will use results from my research to highlight some of the key uncertainties related to global change and lakes, as well as recent developments by aquatic scientists aimed at predicting, mitigating, and coping with these changes.

Revisiting global body politics in Nepal: A reflexive analysis.

PubMed

Harcourt, Wendy

2016-01-01

Using the example of a human rights training in Nepal, the author looks at global body politics in a reflexive piece on her engagement in development practices that translate western feminist ideas on gender inequality and empowerment via UN human rights policies into non-western contexts. It firsts look at postcolonial and critical literature on feminist engagement in gender and development processes including a discussion on the concept of global body politics before examining briefly the framing of gender-based violence in Nepal. The core of the paper is a reflexive analysis and interrogation of the training in Nepal in order to bring out the tensions and contradictions around western developmental, feminist and human rights discourses. The discussion looks at how difficult it is for feminist, human rights and developmental discourses and practices to unmoor themselves from the notion of the 'expert' and those who do the rights/work/righting rights training and those who are perennially seen as requiring training. The conclusion reflects on possibilities of other epistemic practices found in intercultural dialogues.

Human impacts on 20th century fire dynamics and implications for global carbon and water trajectories

NASA Astrophysics Data System (ADS)

Li, F.; Lawrence, D. M.; Bond-Lamberty, B. P.

2017-12-01

Fire is a fundamental Earth system process and the primary ecosystem disturbance on the global scale. It affects carbon and water cycles through its impact on terrestrial ecosystems, and at the same time, is regulated by weather and climate, vegetation characteristics, and, importantly, human ignition and efforts to suppress fires (i.e., the direct human effect on fire). Here, we utilize the Community Land Model version 4.5 (CLM4.5) to generate a quantitative understanding of the impacts on fire dynamics and associated carbon and water cycling that can be attributed to changes in human ignition and suppression over the 20th century. We find that the net impact of increases in human ignition and suppression significantly reduce the 20th century averaged global burned area by 38 Mha/yr. The reduction increases since 1920, rising to 103 Mha/yr less burned area at the end of the century. Land carbon gain is weakened by 17% over the 20th century, mainly due to increased human deforestation fires and associated escape fires (i.e., degradation fires) in the tropical humid forests, even though the decrease in burned area in many other regions due to human fire suppression acts to increase land carbon gain. The direct human effect on fire also weakens the 20th century upward trend of global runoff by 6%, and enhances the upward trend in global evaportranspiration since 1945 by 7%. In addition, the above impacts in densely populated, highly developed (if population density > 0.1 person/km2), or moderately populated and developed regions are of opposite sign to those in other regions. Our study suggests that particular attention should be paid to human deforestation and degradation fires in the tropical humid forests when reconstructing and projecting fire carbon emissions and net atmosphere-land carbon exchange and estimating resultant impacts of direct human effect on fire.

Global Change and Environmental Hazards: Is the World Becoming More Disastrous? Hands-On! Developing Active Learning Modules on the Human Dimensions of Global Change.

ERIC Educational Resources Information Center

Mitchell, Jerry T.; Cutter, Susan L.

This learning module aims to engage students in problem solving, critical thinking, scientific inquiry, and cooperative learning. The module is appropriate for use in any introductory or intermediate undergraduate course that focuses on human-environment relationships. The module introduces the complexities in the relationships among environmental…

Education Service Contracting in the Philippines: Human Rights as Trumps, Goals, or Policy Talk?

ERIC Educational Resources Information Center

Baum, Donald R.

2012-01-01

In recent years, the goals and purposes of education within the international development discourse have shifted significantly away from education for productivity or human capital development and towards education for the fulfillment of the individual through human rights. The current global education climate provides governments with an…

Ecology, Phenomenology, and Culture: Developing a Language for Sustainability

ERIC Educational Resources Information Center

Howard, Patrick

2008-01-01

Education is central to two recent international efforts to address an impending ecological global crisis. "The Earth Charter" and the UN document "Decade for Education for Sustainable Development 2005-2014" challenge all people to consider the socio-ecological, ethical, local and global dimensions of human life. These…

Evaluating Sustainable Development Solutions Quantitatively: Competence Modelling for GCE and ESD

ERIC Educational Resources Information Center

Böhm, Marko; Eggert, Sabina; Barkmann, Jan; Bögeholz, Susanne

2016-01-01

To comprehensively address global environmental challenges such as biodiversity loss, citizens need an understanding of the socio-economic fundamentals of human behaviour in relation to natural resources. We argue that Global Citizenship Education and Education for Sustainable Development provide a core set of socio-economic competencies that can…

Earth applications of closed ecological systems: Relevance to the development of sustainability in our global biosphere

NASA Astrophysics Data System (ADS)

Nelson, M.; Allen, J.; Ailing, A.; Dempster, W. F.; Silverstone, S.

The parallels between the challenges facing bioregenerative life support in artificial closed ecological systems and those in our global biosphere are striking. At the scale of the current global technosphere and expanding human population, it is increasingly obvious that the biosphere can no longer safely buffer and absorb technogenic and anthropogenic pollutants. The loss of biodiversity, reliance on non-renewable natural resources, and conversion of once wild ecosystems for human use with attendant desertification/soil erosion, has led to a shift of consciousness and the widespread call for sustainability of human activities. For researchers working on bioregenerative life support in closed systems, the small volumes and faster cycling times than in the Earth's biosphere make it starkly clear that systems must be designed to ensure renewal of water and atmosphere, nutrient recycling, production of healthy food, and safe environmental methods of maintaining technical systems. The development of technical systems that can be fully integrated and supportive of living systems is a harbinger of new perspectives as well as technologies in the global environment. In addition, closed system bioregenerative life support offers opportunities for public education and consciousness changing of how to live with our global biosphere.

Global Change and Human Consumption of Freshwater Driven by Flow Regulation and Irrigation

NASA Astrophysics Data System (ADS)

Jaramillo, F.; Destouni, G.

2015-12-01

Recent studies show major uncertainties about the magnitude and key drivers of global freshwater change, historically and projected for the future. The tackling of these uncertainties should be a societal priority to understand: 1) the role of human change drivers for freshwater availability changes, 2) the global water footprint of humanity and 3) the relation of human freshwater consumption to a proposed planetary boundary. This study analyses worldwide hydroclimatic changes, as observed during 1900-2009 in 99 large hydrological basins across all continents. We test whether global freshwater change may be driven by major developments of flow regulation and irrigation (FRI) occurring over this period. Independent categorization of the variability of FRI-impact strength among the studied basins is used to identify statistical basin differences in occurrence and strength of characteristic hydroclimatic signals of FRI. Our results show dominant signals of increasing relative evapotranspiration in basins affected by flow regulation and/or irrigation, in conjunction with decreasing relative intra-annual variability of runoff in basins affected by flow regulation. The FRI-related increase in relative evapotranspiration implies an increase of 4,688 km3/yr in global annual average water flow from land to the atmosphere. This observation-based estimate extends considerably the upper quantification limits of both FRI-driven and total global human consumption of freshwater, as well as the global water footprint of humanity. Our worldwide analysis shows clear FRI-related change signals emerging directly from observations, in spite of large change variability among basins and many other coexisting change drivers in both the atmosphere and the landscape. These results highlight the importance of considering local water use as a key change driver in Earth system studies and modelling, of relevance for global change and human consumption of freshwater.

Cultivating Layered Literacies: Developing the Global Child to Become Tomorrow's Global Citizen

ERIC Educational Resources Information Center

Shulsky, Debra D.; Baker, Sheila F.; Chvala, Terry; Willis, Jana M.

2017-01-01

Disappearing cultural, political and physical boundaries push humanity beyond a one-community perspective. Global citizenry requires a set of literacies that affect the ability to communicate effectively, think critically and act conscientiously. This challenges educators to consider reframing instructional practices and curricular content. The…

Chemical ecology of animal and human pathogen vectors in a changing global climate.

PubMed

Pickett, John A; Birkett, Michael A; Dewhirst, Sarah Y; Logan, James G; Omolo, Maurice O; Torto, Baldwyn; Pelletier, Julien; Syed, Zainulabeuddin; Leal, Walter S

2010-01-01

Infectious diseases affecting livestock and human health that involve vector-borne pathogens are a global problem, unrestricted by borders or boundaries, which may be exacerbated by changing global climate. Thus, the availability of effective tools for control of pathogen vectors is of the utmost importance. The aim of this article is to review, selectively, current knowledge of the chemical ecology of pathogen vectors that affect livestock and human health in the developed and developing world, based on key note lectures presented in a symposium on "The Chemical Ecology of Disease Vectors" at the 25th Annual ISCE meeting in Neuchatel, Switzerland. The focus is on the deployment of semiochemicals for monitoring and control strategies, and discusses briefly future directions that such research should proceed along, bearing in mind the environmental challenges associated with climate change that we will face during the 21st century.

Lessons for the anthropocene from the recent past: Tobacco use, HIV/AIDS, and social transformation

NASA Astrophysics Data System (ADS)

Travis, Charles; Holm, Poul

2017-09-01

In light of the dilemma of global climate change that we have presented ourselves with in the twenty-first century and beyond, many researchers express despair at the ability of humans and societies to change behavior. The paper identifies how global humanity at individual, institutional, and governmental levels have addressed life-threatening dangers in the recent past and begun processes of long-term corrective action. The paper thus discusses global social transformations from the recent past in regards to tobacco use and HIV/AIDS, to think about how Hannah Arendt's concept of the Polis detailed in The Human Condition (1958) may be engaged to address the human dimensions of climate change. As an output of the Andrew W. Mellon European Observatory of the New Human Condition, this paper's focus is commensurate with the thrust of this special issue of Global and Planetary Change which considers climate change to be more of a crisis in the human condition than an environmental problem. Arendt's concept of the Polis provides a framework for a better understanding of change in behavior, preference and motivation. We argue that her perspectives are central to developing multi and inter-disciplinary humanities, social science, science and business perspectives to mobilize collective human action towards adapting to and mitigating the social and environmental threats of global climate change.

Thinking Out of the Box: A Green and Social Climate Fund

PubMed Central

Ooms, Gorik; van de Pas, Remco; Decoster, Kristof; Hammonds, Rachel

2017-01-01

Solomon Benatar’s paper "Politics, Power, Poverty and Global Health: Systems and Frames" examines the inequitable state of global health challenging readers to extend the discourse on global health beyond conventional boundaries by addressing the interconnectedness of planetary life. Our response explores existing models of international cooperation, assessing how modifying them may achieve the twin goals of ensuring healthy people and planet. First, we address why the inequality reducing post World War II European welfare model, if implemented state-by-state, is unfit for reducing global inequality and respecting environmental boundaries. Second, we argue that to advance beyond the ‘Westphalian,’ human centric thinking integral to global inequality and climate change requires challenging the logic of global economic integration and exploring the politically infeasible. In conclusion, we propose social policy focused changes to the World Trade Organisation (WTO) and a Green and Social Climate Fund, financed by new global greenhouse gas charges, both of which could advance human and planetary health. Recent global political developments may offer a small window of opportunity for out of the box proposals that could be advanced by concerted and united advocacy by global health activists, environmental activists, human rights activists, and trade unions. PMID:28949466

A microbial perspective of human developmental biology.

PubMed

Charbonneau, Mark R; Blanton, Laura V; DiGiulio, Daniel B; Relman, David A; Lebrilla, Carlito B; Mills, David A; Gordon, Jeffrey I

2016-07-07

When most people think of human development, they tend to consider only human cells and organs. Yet there is another facet that involves human-associated microbial communities. A microbial perspective of human development provides opportunities to refine our definitions of healthy prenatal and postnatal growth and to develop innovative strategies for disease prevention and treatment. Given the dramatic changes in lifestyles and disease patterns that are occurring with globalization, we issue a call for the establishment of 'human microbial observatories' designed to examine microbial community development in birth cohorts representing populations with diverse anthropological characteristics, including those undergoing rapid change.

Why Geo-Humanities

NASA Astrophysics Data System (ADS)

Graells, Robert Casals i.; Sibilla, Anna; Bohle, Martin

2016-04-01

Anthropogenic global change is a composite process. It consists of societal processes (in the 'noosphere') and natural processes (in the 'bio-geosphere'). The 'noosphere' is the ensemble of social, cultural or political insights ('shared subjective mental concepts') of people. Understanding the composite of societal and natural processes ('human geo-biosphere intersections'), which shapes the features of anthropogenic global change, would benefit from a description that draws equally on natural sciences, social sciences and humanities. To that end it is suggested to develop a concept of 'geo-humanities': This essay presents some aspects of its scope, discussing "knowledge that is to manage", "intentions that are to shape", "choices that are to justify" and "complexity that is to handle". Managing knowledge: That people understand anthropogenic global change requires their insights into how 'human geosphere intersections' function. Insights are formed ('processed') in the noosphere by means of interactions between people. Understanding how 'human geosphere intersections' functions combines scientific, engineering and economic studies with studies of the dynamics of the noosphere. Shaping intentions: During the last century anthropogenic global change developed as the collateral outcome of humankind's accumulated actions. It is caused by the number of people, the patterns of their consumption of resources, and the alterations of their environments. Nowadays, anthropogenic global chance is either an intentional negligence or a conscious act. Justifying choices: Humanity has alternatives how to alter Earth at planetary scale consciously. For example, there is a choice to alter the geo-biosphere or to adjust the noosphere. Whatever the choice, it will depend on people's world-views, cultures and preferences. Thus beyond issues whether science and technology are 'sound' overarching societal issues are to tackle, such as: (i) how to appropriate and distribute natural resources for what cost, (ii) what are intended collateral effects, or (iii) what is the risk of non-intended collateral effects? Handling complexity: Consciously altering Earth at a planetary scale is ambitious, although it fits well into the historical development of industrialised societies and their paradigms how to handle change. Still, action at a planetary scale goes beyond any actual use-case that may serve as a reference. Furthermore, the available technological means, scientific understanding and resources impose limits, and, second, the noosphere is complex given the variety of interacting world-views, cultures and preferences. Summarizing, geo-humanities would study human geosphere intersections. Geo-humanities would address societal and natural process within one frame of reference to understand how attributes of the geo-biosphere and artefacts of the noosphere are aggregated to anthropogenic global change.

Ergonomics and sustainability--challenges from global supply chains.

PubMed

Hasle, Peter; Jensen, Per Langaa

2012-01-01

The development of globalised supply chains is a major challenge for sustainability. For several years, there has been discussion within the profession whether and how ergonomics and human factors can play a role. Based on our research, we have identified five major challenges from global supply chains especially related to the social aspects of sustainability: (1) criteria for social sustainability, (2) the role of key performance indicators in the management of supply chains, (3) the constant changes in supply chains, (4) the challenge in establishing participation, and (5) the development of agency and regulatory mechanisms. There are obviously no clear and simple solutions to these challenges. One possible avenue for progress might lie in acquiring a greater understanding of the challenges from global supply chains and developing a strategy which combines social and long-term business sustainability. Starting from such a basis, the next step would be to find ways for the ergonomics and human factors community to create international collaboration which can impact specific global supply chains.

Earth Applications of Closed Ecological Systems: Relevance to the Development of Sustainability in our Global Biosphere

NASA Astrophysics Data System (ADS)

Dempster, W.; van Thillo, M.; Alling, A.; Allen, J.; Silverstone, S.; Nelson, M.

The parallels between the challenges facing bioregenerative life support and closed ecological systems and those in our global biosphere are striking. At the scale of the current global technosphere and human population, it is increasingly obvious that the biosphere can no longer be counted on to be vast enough to safely buffer and absorb technogenic and anthropogenic pollutants. With an increasing percentage of the world's natural resources and primary productivity being dictated by, and directed to, humans, our species is starting to appreciate its survival and quality of life depends on regulating its activities, and insuring that crucial biogeochemical cycles continue to function. This shift of consciousness has led to the widespread call for moving towards the sustainability of human activities. For researchers working on bioreenerative life support, the small volumes and faster cycling times have made it obvious that systems must be created in to ensure renewal of water and atmosphere, nutrient recycling, and where all technical systems can be safely integrated with the maintenance of safe environmental conditions. The development of technical systems that can be fully integrated with the living systems that they support should be a harbinger of new perspectives in the global environment. The paper will review some of these environmental technologies which are emerging from bioregenerative life support system research such as high-yield intensive agricultural methods, waste treatment and nutrient recycling, air purification, modeling, sensor and control systems and their potential applications in the global biosphere. In addition, a review of the human experience in closed ecological systems shows that these can offer opportunities for public education and consciousness-changing of how humans regard our global biosphere.

Vaccines and global health.

PubMed

Greenwood, Brian; Salisbury, David; Hill, Adrian V S

2011-10-12

Vaccines have made a major contribution to global health in recent decades but they could do much more. In November 2011, a Royal Society discussion meeting, 'New vaccines for global health', was held in London to discuss the past contribution of vaccines to global health and to consider what more could be expected in the future. Papers presented at the meeting reviewed recent successes in the deployment of vaccines against major infections of childhood and the challenges faced in developing vaccines against some of the world's remaining major infectious diseases such as human immunodeficiency virus (HIV), malaria and tuberculosis. The important contribution that development of more effective veterinary vaccines could make to global health was also addressed. Some of the social and financial challenges to the development and deployment of new vaccines were reviewed. The latter issues were also discussed at a subsequent satellite meeting, 'Accelerating vaccine development', held at the Kavli Royal Society International Centre. Delegates at this meeting considered challenges to the more rapid development and deployment of both human and veterinary vaccines and how these might be addressed. Papers based on presentations at the discussion meeting and a summary of the main conclusions of the satellite meeting are included in this issue of Philosophical Transactions of the Royal Society B.

Defining the Antigenic Structure of the Henipavirus Attachment (G) Glycoprotein: Implications for the Fusion Mechanism

DTIC Science & Technology

2009-01-01

and therapeutic modalities resulting in significant global decreases in the health burden of infectious agents . As early as the mid 1940s widespread...of rapid development in prophylactic and therapeutic modalities resulting in significant global decreases in the health burden of infectious agents ...Human herpesvirus 8 pathogen detection/ identification Human metapneumovirus technology Group A Streptococcus (toxic shock syndrome

Human impacts on morphodynamic thresholds in estuarine systems

NASA Astrophysics Data System (ADS)

Wang, Z. B.; Van Maren, D. S.; Ding, P. X.; Yang, S. L.; Van Prooijen, B. C.; De Vet, P. L. M.; Winterwerp, J. C.; De Vriend, H. J.; Stive, M. J. F.; He, Q.

2015-12-01

Many estuaries worldwide are modified, primarily driven by economic gain or safety. These works, combined with global climate changes heavily influence the morphologic development of estuaries. In this paper, we analyze the impact of human activities on the morphodynamic developments of the Scheldt Estuary and the Wadden Sea basins in the Netherlands and the Yangtze Estuary in China at various spatial scales, and identify mechanisms responsible for their change. Human activities in these systems include engineering works and dredging activities for improving and maintaining the navigation channels, engineering works for flood protection, and shoreline management activities such as land reclamations. The Yangtze Estuary is influenced by human activities in the upstream river basin as well, especially through the construction of many dams. The tidal basins in the Netherlands are also influenced by human activities along the adjacent coasts. Furthermore, all these systems are influenced by global changes through (accelerated) sea-level rise and changing weather patterns. We show that the cumulative impacts of these human activities and global changes may lead to exceeding thresholds beyond which the morphology of the tidal basins significantly changes, and loses its natural characteristics. A threshold is called tipping point when the changes are even irreversible. Knowledge on such thresholds or tipping points is important for the sustainable management of these systems. We have identified and quantified various examples of such thresholds and/or tipping points for the morphodynamic developments at various spatial and temporal scales. At the largest scale (mega-scale) we consider the sediment budget of a tidal basin as a whole. A smaller scale (macro-scale) is the development of channel structures in an estuary, especially the development of two competing channels. At the smallest scale (meso-scale) we analyze the developments of tidal flats and the connecting channels.

Social change, cultural evolution, and human development.

PubMed

Greenfield, Patricia M

2016-04-01

Social change has accelerated globally. Greenfield's interdisciplinary and multilevel theory of social change and human development provides a unified framework for exploring implications of these changes for cultural values, learning environments/socialization processes, and human development/behavior. Data from societies where social change has occurred in place (US, China, and Mexico) and a community where it has occurred through international migration (Mexican immigrants in the US) elucidate these implications. Globally dominant sociodemographic trends are: rural to urban, agriculture to commerce, isolation to interconnectedness, less to more education, less to more technology, lesser to greater wealth, and larger to smaller families/households. These trends lead to both cultural losses (e.g., interdependence/collectivism, respect, tradition, contextualized thinking) and cultural gains (e.g., independence/individualism, equality, innovation, abstraction). Copyright © 2015. Published by Elsevier Ltd.

Applying evolutionary biology to address global challenges

PubMed Central

Carroll, Scott P.; Jørgensen, Peter Søgaard; Kinnison, Michael T.; Bergstrom, Carl T.; Denison, R. Ford; Gluckman, Peter; Smith, Thomas B.; Strauss, Sharon Y.; Tabashnik, Bruce E.

2014-01-01

Two categories of evolutionary challenges result from escalating human impacts on the planet. The first arises from cancers, pathogens and pests that evolve too quickly, and the second from the inability of many valued species to adapt quickly enough. Applied evolutionary biology provides a suite of strategies to address these global challenges that threaten human health, food security, and biodiversity. This review highlights both progress and gaps in genetic, developmental and environmental manipulations across the life sciences that either target the rate and direction of evolution, or reduce the mismatch between organisms and human-altered environments. Increased development and application of these underused tools will be vital in meeting current and future targets for sustainable development. PMID:25213376

Globalization and the trade in human body parts.

PubMed

Harrison, T

1999-02-01

Since the early 1980s, the number and variety of organ transplantations has increased enormously worldwide. Accompanying this increase has been the emergence of a market for human body parts. This paper argues that, while the trade in human body parts is conditioned by technological advances, it must be understood in the broader context of globalization, specifically the extension and intensification of a capitalist mode of exchange. In this regard, it is argued that the trade in human body parts mirrors the "normal" system of unequal exchanges that mark other forms of trade between the developed and undeveloped regions of the world.

Global issues and opportunities for optimized retinoblastoma care.

PubMed

Gallie, Brenda L; Zhao, Junyang; Vandezande, Kirk; White, Abigail; Chan, Helen S L

2007-12-01

The RB1 gene is important in all human cancers. Studies of human retinoblastoma point to a rare retinal cell with extreme dependency on RB1 for initiation but not progression to full malignancy. In developed countries, genetic testing within affected families can predict children at high risk of retinoblastoma before birth; chemotherapy with local therapy often saves eyes and vision; and mortality is 4%. In less developed countries where 92% of children with retinoblastoma are born, mortality reaches 90%. Global collaboration is building for the dramatic change in mortality that awareness, simple expertise and therapies could achieve in less developed countries. Copyright 2007 Wiley-Liss, Inc.

Under the (legal) radar screen: global health initiatives and international human rights obligations.

PubMed

Hammonds, Rachel; Ooms, Gorik; Vandenhole, Wouter

2012-11-15

Given that many low income countries are heavily reliant on external assistance to fund their health sectors the acceptance of obligations of international assistance and cooperation with regard to the right to health (global health obligations) is insufficiently understood and studied by international health and human rights scholars. Over the past decade Global Health Initiatives, like the Global Fund to fight AIDS, Tuberculosis and Malaria (Global Fund) have adopted novel approaches to engaging with stakeholders in high and low income countries. This article explores how this experience impacted on acceptance of the international obligation to (help) fulfil the right to health beyond borders. The authors conducted an extensive review of international human rights law literature, transnational legal process literature, global public health literature and grey literature pertaining to Global Health Initiatives. To complement this desk work and deepen their understanding of how and why different legal norms evolve the authors conducted 19 in-depth key informant interviews with actors engaged with three stakeholders; the European Union, the United States and Belgium. The authors then analysed the interviews through a transnational legal process lens. Through according value to the process of examining how and why different legal norms evolve transnational legal process offers us a tool for engaging with the dynamism of developments in global health suggesting that operationalising global health obligations could advance the right to health for all. In many low-income countries the health sector is heavily dependent on external assistance to fulfil the right to health of people thus it is vital that policies and tools for delivering reliable, long-term assistance are developed so that the right to health for all becomes more than a dream. Our research suggests that the Global Fund experience offers lessons to build on.

The pyrohealth transition: how combustion emissions have shaped health through human history.

PubMed

Johnston, Fay H; Melody, Shannon; Bowman, David M J S

2016-06-05

Air pollution from landscape fires, domestic fires and fossil fuel combustion is recognized as the single most important global environmental risk factor for human mortality and is associated with a global burden of disease almost as large as that of tobacco smoking. The shift from a reliance on biomass to fossil fuels for powering economies, broadly described as the pyric transition, frames key patterns in human fire usage and landscape fire activity. These have produced distinct patters of human exposure to air pollution associated with the Agricultural and Industrial Revolutions and post-industrial the Earth global system-wide changes increasingly known as the Anthropocene. Changes in patterns of human fertility, mortality and morbidity associated with economic development have been previously described in terms of demographic, epidemiological and nutrition transitions, yet these frameworks have not explicitly considered the direct consequences of combustion emissions for human health. To address this gap, we propose a pyrohealth transition and use data from the Global Burden of Disease (GBD) collaboration to compare direct mortality impacts of emissions from landscape fires, domestic fires, fossil fuel combustion and the global epidemic of tobacco smoking. Improving human health and reducing the environmental impacts on the Earth system will require a considerable reduction in biomass and fossil fuel combustion.This article is part of the themed issue 'The interaction of fire and mankind'. © 2016 The Author(s).

The pyrohealth transition: how combustion emissions have shaped health through human history

PubMed Central

Johnston, Fay H.; Melody, Shannon

2016-01-01

Air pollution from landscape fires, domestic fires and fossil fuel combustion is recognized as the single most important global environmental risk factor for human mortality and is associated with a global burden of disease almost as large as that of tobacco smoking. The shift from a reliance on biomass to fossil fuels for powering economies, broadly described as the pyric transition, frames key patterns in human fire usage and landscape fire activity. These have produced distinct patters of human exposure to air pollution associated with the Agricultural and Industrial Revolutions and post-industrial the Earth global system-wide changes increasingly known as the Anthropocene. Changes in patterns of human fertility, mortality and morbidity associated with economic development have been previously described in terms of demographic, epidemiological and nutrition transitions, yet these frameworks have not explicitly considered the direct consequences of combustion emissions for human health. To address this gap, we propose a pyrohealth transition and use data from the Global Burden of Disease (GBD) collaboration to compare direct mortality impacts of emissions from landscape fires, domestic fires, fossil fuel combustion and the global epidemic of tobacco smoking. Improving human health and reducing the environmental impacts on the Earth system will require a considerable reduction in biomass and fossil fuel combustion. This article is part of the themed issue ‘The interaction of fire and mankind’. PMID:27216506

Human Dignity and Humiliation Studies: A Global Network Advancing Dignity through Dialogue

ERIC Educational Resources Information Center

Lindner, Evelin G.; Hartling, Linda M.; Spalthoff, Ulrich

2011-01-01

Human rights are universally based on the concept of human dignity. Various international organizations are developing the theoretical, legal, and political framework for human rights. The underlying concept of human dignity is less disputed, but also receives less attention. This shortcoming is addressed by a worldwide group of scholars and…

Human developmental biology viewed from a microbial perspective

PubMed Central

Charbonneau, Mark R.; Blanton, Laura V.; DiGiulio, Daniel B.; Relman, David A.; Lebrilla, Carlito B.; Mills, David A.; Gordon, Jeffrey I.

2017-01-01

Preface Most people think of human development only in terms of ‘human’ cells and organs. Here, we discuss another facet involving human-associated microbial communities. A microbial perspective of human development provides opportunities to refine our definitions of healthy pre- and postnatal growth and to develop new strategies for disease prevention and treatment. Considering the dramatic changes in lifestyles and disease patterns that are occurring with globalization, we issue a call for human microbial observatory programs designed to examine microbial community development in birth cohorts representing populations with diverse anthropologic characteristics, including those undergoing rapid change. PMID:27383979

Massive yet grossly underestimated global costs of invasive insects

PubMed Central

Bradshaw, Corey J. A.; Leroy, Boris; Bellard, Céline; Roiz, David; Albert, Céline; Fournier, Alice; Barbet-Massin, Morgane; Salles, Jean-Michel; Simard, Frédéric; Courchamp, Franck

2016-01-01

Insects have presented human society with some of its greatest development challenges by spreading diseases, consuming crops and damaging infrastructure. Despite the massive human and financial toll of invasive insects, cost estimates of their impacts remain sporadic, spatially incomplete and of questionable quality. Here we compile a comprehensive database of economic costs of invasive insects. Taking all reported goods and service estimates, invasive insects cost a minimum of US$70.0 billion per year globally, while associated health costs exceed US$6.9 billion per year. Total costs rise as the number of estimate increases, although many of the worst costs have already been estimated (especially those related to human health). A lack of dedicated studies, especially for reproducible goods and service estimates, implies gross underestimation of global costs. Global warming as a consequence of climate change, rising human population densities and intensifying international trade will allow these costly insects to spread into new areas, but substantial savings could be achieved by increasing surveillance, containment and public awareness. PMID:27698460

78 FR 13359 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-27

... Institute of Child Health and Human Development Special Emphasis Panel; Global Partnership for Social Science AIDS Research (R24). Date: March 21-22, 2013. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and...

Human Rights and Teaching for Social Justice

ERIC Educational Resources Information Center

Landorf, Hilary

2010-01-01

According to the author, teaching for social justice entails the acquisition of the following learning outcomes: (1) knowledge of the meaning, historical development, and application of human rights; (2) ability to analyze human rights from multiple perspectives; and (3) willingness to address human rights issues in local, global, intercultural,…

The astysphere and urban geochemistry-a new approach to integrate urban systems into the geoscientific concept of spheres and a challenging concept of modern geochemistry supporting the sustainable development of planet earth.

PubMed

Norra, Stefan

2009-07-01

In 1875, the geoscientist Walter Suess introduced several spheres, such as the lithosphere and the atmosphere to promote a comprehensive understanding of the system earth. Since then, this idea became the dominating concept for the understanding of the distribution of chemical elements in the system earth. Meanwhile, due to the importance of human beings on global element fluxes, the term anthroposphere was introduced. Nevertheless, in face of the ongoing urbanization of the earth, this concept is not any more adequate enough to develop a comprehensive understanding of global element fluxes in and between solid, liquid, and gaseous phases. This article discusses a new concept integrating urbanization into the geoscientific concept of spheres. No geological exogenic force has altered the earth's surface during the last centuries in such an extent as human activity. Humans have altered the morphology and element balances of the earth by establishing agrosystems first and urban systems later. Currently, urban systems happen to become the main regulators for fluxes of many elements on a global scale due to ongoing industrial and economic development and a growing number of inhabitants. Additionally, urban systems are constantly expanding and cover more and more former natural and agricultural areas. For nature, urban systems are new phenomena, which never existed in previous geological eras. The process of the globe's urbanization concurrently is active with the global climate change. In fact, urban systems are a major emitter for climate active gases. Thus, beside the global changes in economy and society, urbanization is an important factor within the global change of nature as is already accepted for climate, ecosystems, and biodiversity. Due to the fact that urbanization has become a global process shaping the earth and that the urban systems are globally cross-linked among each other, a new geoscientific sphere has to be introduced: the astysphere. This sphere comprises the parts of the earth influenced by urban systems. Accepting urbanization as global ongoing process forming the astysphere comprehensively copes with the growing importance of urbanization on the creation of present geologic formations. Anthropogenic activities occur mainly in rural and urban environments. For long lasting periods of human history, human activities mainly were focused on hunting and agriculture, but since industrialization, urbanized areas became increasingly important for the material and energy fluxes of earth. Thus, it seems appropriate to classify the anthroposphere into an agriculturally and an urban-dominated sphere, which are the agrosphere (Krishna 2003) and the astysphere (introduced by Norra 2007). We have to realize that urban systems are deposits, consumers, and transformers of resources interacting among each other and forming a network around the globe. Since the future of human mankind depends on the sustainable use of available resources, only a global and holistic view of the cross-linked urban systems forming together the astysphere provide the necessary geoscientific background understanding for global urban material and energy fluxes. If we want to ensure worth-living conditions for future generations of mankind, we have to develop global models of the future needs for resources by the global metasystem of urban systems, called astysphere. The final vision for geoscientific research on the astysphere must be to design models describing the global process of urbanization of the earth and the development of the astysphere with respect to fluxes of materials, elements, and energy as well as with respect to the forming of the earth's face. Besides that, just from the viewpoint of fundamental research, the geoscientific concept of spheres has to be complemented by the astysphere if this concept shall fully represent the system earth.

Web Map Services (WMS) Global Mosaic

NASA Technical Reports Server (NTRS)

Percivall, George; Plesea, Lucian

2003-01-01

The WMS Global Mosaic provides access to imagery of the global landmass using an open standard for web mapping. The seamless image is a mosaic of Landsat 7 scenes; geographically-accurate with 30 and 15 meter resolutions. By using the OpenGIS Web Map Service (WMS) interface, any organization can use the global mosaic as a layer in their geospatial applications. Based on a trade study, an implementation approach was chosen that extends a previously developed WMS hosting a Landsat 5 CONUS mosaic developed by JPL. The WMS Global Mosaic supports the NASA Geospatial Interoperability Office goal of providing an integrated digital representation of the Earth, widely accessible for humanity's critical decisions.

Managing Identifiers for Elements of Provenance of the Third National Climate Assessment in the Global Change Information System (Invited)

NASA Astrophysics Data System (ADS)

Tilmes, C.; Aulenbach, S.; Duggan, B.; Goldstein, J.

2013-12-01

A Federal Advisory Committee (The "National Climate Assessment and Development Advisory Committee" or NCADAC) has overseen the development of a draft climate report that after extensive review will be considered by the Federal Government in the Third National Climate Assessment (NCA). This comprehensive report (1) Integrates, evaluates, and interprets the findings of the Program and discusses the scientific uncertainties associated with such findings; (2) Analyzes the effects of global change on the natural environment, agriculture, energy production and use, land and water resources, transportation, human health and welfare, human social systems, and biological diversity; and (3) Analyzes current trends in global change, both human-induced and natural, and projects major trends for the subsequent 25 to 100 years. The U.S. Global Change Program (USGCRP), composed of the 13 federal agencies most concerned with global change, is building a Global Change Information System (GCIS) that will ultimately organize access to all of the research, data, and information about global change from across the system. A prototype of the system has been constructed that captures and presents all of the elements of provenance of the NCA through a coherent data model and friendly front end web site. This work will focus on the globally unique and persistent identifiers used to reference and organize those items. These include externally referenced items, such as DOIs used by scientific journal publishers for research articles or by agencies as dataset identifiers, as well as our own internal approach to identifiers, our overall data model and experiences managing persistent identifiers within the GCIS.

National prevalence of coronary heart disease and its relationship with human development index: A systematic review.

PubMed

Zhu, Ke-Fu; Wang, Yu-Ming; Zhu, Jin-Zhou; Zhou, Qin-Yi; Wang, Ning-Fu

2016-03-01

Coronary heart disease has become a major health concern over the past several decades. Several reviews have assessed the effects of socioeconomic status on the coronary heart disease epidemic in communities and countries, but only a few reviews have been performed at a global level. This study was to explore the relationship between the prevalence of coronary heart disease and socioeconomic development worldwide using the Human Development Index. Systematic review. The data in this study were collected from the MEDLINE database. Cross-sectional studies reporting the prevalence of coronary heart disease until November 2014 were collected. The Human Development Index was sourced from the United Nations Development Programme Database and was used to measure the socioeconomic achievements of countries. Each country was classified as a developing or developed country based on its level of development according to the Human Development Index value. Based on the data analysis on the global level, coronary heart disease prevalence had no association with the national Human Development Index (rho = 0.07). However, there was a positive association between coronary heart disease prevalence and the national Human Development Index in developing countries, although a negative association existed in developed countries (rho = 0.47 and -0.34, respectively). In addition, the past decades have witnessed a growing coronary heart disease epidemic in developing countries, with reverse trends observed in developed countries (P = 0.021 and 0.002, respectively). With the development of socioeconomic status, as measured by the Human Development Index, the prevalence of coronary heart disease is growing in developing countries, while declining in developed countries. Future research needs to pay more attention to the reasonable allocation of medical resources and control of coronary heart disease risk factors. © The European Society of Cardiology 2015.

Staying alive: the psychology of human survival

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walsh, R.

Human beings need not live on the edge of global extinction. The author advocates that the problems created by greed, aggression, and ignorance (such as pollution, nuclear weaponry, and ecological imbalances) can be altered by individual and collective effort to confront inner confusion. By making the effort to educate each other, changing beliefs about themselves and others, and reducing fear and defensiveness, people can work toward developing the positive global psychology that the author outlines. Using the principles of behavior modification, he reinterprets motivation to apply to a global therapy based on optimism and good will. An appendix gives themore » names and addresses of organizations working toward the resolution of global problems. 174 references.« less

Global epidemiology of non-influenza RNA respiratory viruses: data gaps and a growing need for surveillance.

PubMed

Tang, Julian W; Lam, Tommy T; Zaraket, Hassan; Lipkin, W Ian; Drews, Steven J; Hatchette, Todd F; Heraud, Jean-Michel; Koopmans, Marion P

2017-10-01

Together with influenza, the non-influenza RNA respiratory viruses (NIRVs), which include respiratory syncytial virus, parainfluenza viruses, coronavirus, rhinovirus, and human metapneumovirus, represent a considerable global health burden, as recognised by WHO's Battle against Respiratory Viruses initiative. By contrast with influenza viruses, little is known about the contemporaneous global diversity of these viruses, and the relevance of such for development of pharmaceutical interventions. Although far less advanced than for influenza, antiviral drugs and vaccines are in different stages of development for several of these viruses, but no interventions have been licensed. This scarcity of global genetic data represents a substantial knowledge gap and impediment to the eventual licensing of new antiviral drugs and vaccines for NIRVs. Enhanced genetic surveillance will assist and boost research and development into new antiviral drugs and vaccines for these viruses. Additionally, understanding the global diversity of respiratory viruses is also part of emerging disease preparedness, because non-human coronaviruses and paramyxoviruses have been listed as priority concerns in a recent WHO research and development blueprint initiative for emerging infectious diseases. In this Personal View, we explain further the rationale for expanding the genetic database of NIRVs and emphasise the need for greater investment in this area of research. Copyright © 2017 Elsevier Ltd. All rights reserved.

Earth applications of closed ecological systems: relevance to the development of sustainability in our global biosphere.

PubMed

Nelson, M; Allen, J; Alling, A; Dempster, W F; Silverstone, S

2003-01-01

The parallels between the challenges facing bioregenerative life support in artificial closed ecological systems and those in our global biosphere are striking. At the scale of the current global technosphere and expanding human population, it is increasingly obvious that the biosphere can no longer safely buffer and absorb technogenic and anthropogenic pollutants. The loss of biodiversity, reliance on non-renewable natural resources, and conversion of once wild ecosystems for human use with attendant desertification/soil erosion, has led to a shift of consciousness and the widespread call for sustainability of human activities. For researchers working on bioregenerative life support in closed systems, the small volumes and faster cycling times than in the Earth's biosphere make it starkly clear that systems must be designed to ensure renewal of water and atmosphere, nutrient recycling, production of healthy food, and safe environmental methods of maintaining technical systems. The development of technical systems that can be fully integrated and supportive of living systems is a harbinger of new perspectives as well as technologies in the global environment. In addition, closed system bioregenerative life support offers opportunities for public education and consciousness changing of how to live with our global biosphere. c2003 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Global Inequalities in Cervical Cancer Incidence and Mortality are Linked to Deprivation, Low Socioeconomic Status, and Human Development

PubMed Central

Singh, Gopal K.; Azuine, Romuladus E.; Siahpush, Mohammad

2012-01-01

Objectives This study examined global inequalities in cervical cancer incidence and mortality rates as a function of cross-national variations in the Human Development Index (HDI), socioeconomic factors, Gender Inequality Index (GII), and healthcare expenditure. Methods Age-adjusted incidence and mortality rates were calculated for women in 184 countries using the 2008 GLOBOCAN database, and incidence and mortality trends were analyzed using the WHO cancer mortality database. Log-linear regression was used to model annual trends, while OLS and Poisson regression models were used to estimate the impact of socioeconomic and human development factors on incidence and mortality rates. Results Cervical cancer incidence and mortality rates varied widely, with many African countries such as Guinea, Zambia, Comoros, Tanzania, and Malawi having at least 10-to-20-fold higher rates than several West Asian, Middle East, and European countries, including Iran, Saudi Arabia, Syria, Egypt, and Switzerland. HDI, GII, poverty rate, health expenditure per capita, urbanization, and literacy rate were all significantly related to cervical cancer incidence and mortality, with HDI and poverty rate each explaining >52% of the global variance in mortality. Both incidence and mortality rates increased in relation to lower human development and higher gender inequality levels. A 0.2 unit increase in HDI was associated with a 20% decrease in cervical cancer risk and a 33% decrease in cervical cancer mortality risk. The risk of a cervical cancer diagnosis increased by 24% and of cervical cancer death by 42% for a 0.2 unit increase in GII. Higher health expenditure levels were independently associated with decreased incidence and mortality risks. Conclusions and Public Health Implications Global inequalities in cervical cancer are clearly linked to disparities in human development, social inequality, and living standards. Reductions in cervical cancer rates are achievable by reducing inequalities in socioeconomic conditions, availability of preventive health services, and women’s social status. PMID:27621956

Global Inequalities in Cervical Cancer Incidence and Mortality are Linked to Deprivation, Low Socioeconomic Status, and Human Development.

PubMed

Singh, Gopal K; Azuine, Romuladus E; Siahpush, Mohammad

2012-01-01

This study examined global inequalities in cervical cancer incidence and mortality rates as a function of cross-national variations in the Human Development Index (HDI), socioeconomic factors, Gender Inequality Index (GII), and healthcare expenditure. Age-adjusted incidence and mortality rates were calculated for women in 184 countries using the 2008 GLOBOCAN database, and incidence and mortality trends were analyzed using the WHO cancer mortality database. Log-linear regression was used to model annual trends, while OLS and Poisson regression models were used to estimate the impact of socioeconomic and human development factors on incidence and mortality rates. Cervical cancer incidence and mortality rates varied widely, with many African countries such as Guinea, Zambia, Comoros, Tanzania, and Malawi having at least 10-to-20-fold higher rates than several West Asian, Middle East, and European countries, including Iran, Saudi Arabia, Syria, Egypt, and Switzerland. HDI, GII, poverty rate, health expenditure per capita, urbanization, and literacy rate were all significantly related to cervical cancer incidence and mortality, with HDI and poverty rate each explaining >52% of the global variance in mortality. Both incidence and mortality rates increased in relation to lower human development and higher gender inequality levels. A 0.2 unit increase in HDI was associated with a 20% decrease in cervical cancer risk and a 33% decrease in cervical cancer mortality risk. The risk of a cervical cancer diagnosis increased by 24% and of cervical cancer death by 42% for a 0.2 unit increase in GII. Higher health expenditure levels were independently associated with decreased incidence and mortality risks. Global inequalities in cervical cancer are clearly linked to disparities in human development, social inequality, and living standards. Reductions in cervical cancer rates are achievable by reducing inequalities in socioeconomic conditions, availability of preventive health services, and women's social status.

United Nations Development Program solicits funds from corporations.

PubMed

Karliner, J; Srivastava, A; Bruno, K

1999-01-01

The Global Sustainable Development Facility (GSDF) project, a collaboration between the U.N. Development Program and a variety of global corporate sponsors, some with poor human rights, labor, and environmental records, has come under criticism from prestigious nongovernmental organizations around the world. A letter to James Gustave Speth, Administrator of the U.N. Development Program, expresses concern about the threat posed by the GSDF project to the independence and credibility of the U.N. Development Program.

What did the Romans ever do for us? Putting humans in global land models

NASA Astrophysics Data System (ADS)

Bierkens, M. F.; Wada, Y.; Dermody, B.; Van Beek, L. P.

2016-12-01

During the late 1980s and early 1990s, awareness of the shortage of global water resources lead to the first detailed global water resources assessments using regional statistics of water use and observations of meteorological and hydrological variables. Shortly thereafter, the first macroscale hydrological models (MHM) appeared. In these models, blue water (i.e., surface water and renewable groundwater) availability was calculated by accumulating runoff over a stream network and comparing it with population densities or with estimated water demand for agriculture, industry and households. In this talk we review the evolution of human impact modelling in global land models with a focus on global water resources, touching upon developments of the last 15 years: i.e. calculating human water scarcity; estimating groundwater depletion; adding dams and reservoirs; fully integrating water use (abstraction, application, consumption, return flow) in the hydrology; simulating the effects of land use change. We identify four major challenges that hamper the further development of integrated water resources modelling and thus prohibit realistic projections of the future terrestrial water cycle in the Anthropocene. These are: 1) including the ability to model infrastructural changes and measures; 2) projecting future water demand and water use and associated measures; 3) including virtual water trade; 4) including land use change and landscape change. While all these challenges will likely benefit from hydro-economics and the newly developing field of socio-hydrology, we also show that especially for challenges 3 and 4 lessons can be drawn from the (pre)historic past. To make this point we provide two case studies: one modelling the virtual water trade in the Roman Empire and one modelling human-landscape interaction in prehistoric Calabria (Italy).

New Technology Tools for Human Development? Towards Policy and Practice for Knowledge Societies in Southern Africa.

ERIC Educational Resources Information Center

Johnson, Phyllis

2002-01-01

Explores the interface of technology and education for human development in southern Africa. Uses the case of Mozambique to describe the challenges presented by the global marketplace and local policy. Outlines the vision of the New Partnership for Africa's Development Centre (SARDC) to reduce the digital divide for Africa. (CAJ)

The impact of HIV/AIDS on human development in African countries.

PubMed

Boutayeb, Abdesslam

2009-11-18

In the present paper, we consider the impact of HIV/AIDS on human development in African countries, showing that, beyond health issues, this disease should and must be seen as a global development concern, affecting all components of human development. Consequently, we stress the necessity of multidisciplinary approaches that model, estimate and predict the real impact of HIV/AIDS on human development of African countries in order to optimise the strategies proposed by national countries, international institutions and their partners. In our search strategy, we relied on secondary information, mainly through National Human Development Reports of some African countries and regular publications released by the United Nations (UN), United Nations Development Programme (UNDP), World Health Organization (WHO) and the World Bank. We restricted ourselves to reports dealing explicitly with the impact of HIV/AIDS on human development in African countries. HIV/AIDS is affecting the global human development of African countries through its devastating impact on health and demographic indicators such as life expectancy at birth, healthcare assistance, age and sex distribution, economic indicators like income, work force, and economic growth, education and knowledge acquisition and other indicators like governance, gender inequality and human rights. On the basis of the national reports reviewed, it appears clearly that HIV/AIDS is no longer a crisis only for the healthcare sector, but presents a challenge to all sectors. Consequently, HIV/AIDS is a development question and should be viewed as such. The disease is impeding development by imposing a steady decline in the key indicators of human development and hence reversing the social and economic gains that African countries are striving to attain. Being at the same time a cause and consequence of poverty and underdevelopment, it constitutes a challenge to human security and human development by diminishing the chances of alleviating poverty and hunger, achieving universal primary education, promoting gender equality, reducing child and maternal mortality, and ensuring environmental sustainability.

People, Pope and Planet: A Hermeneutic and Spectacle Analysis of "Laudato Si'" for Global Citizenship Educators

ERIC Educational Resources Information Center

Gaudelli, William

2017-01-01

Global citizenship education presents a number of challenges for educators, including the wide variety of texts available to be studied. I explore "Laudato Si'," Pope Francis' 2015 statement on global warming and human development. "Laudato Si'" includes contents that are broad, connective, and significant/relevant, making it a…

Human rights in occupational therapy education: A step towards a more occupationally just global society.

PubMed

Crawford, Emma; Aplin, Tammy; Rodger, Sylvia

2017-04-01

Education on human rights will place occupational therapists in a strong position to address societal inequities that limit occupational engagement for many client groups. The imminent changes to the Minimum Standard for the Education of Occupational Therapists engender efforts towards social change and will require university-level human rights education. This education might enhance the profession's influence on disadvantaging social structures in order to effect social change. To contribute to the evidence base for social change education in occupational therapy, this research aims to understand the knowledge, skills, confidence and learning experiences of occupational therapy students who completed a human rights course. Final year occupational therapy students responded to questionnaires which included listing human rights, a human rights scale measuring knowledge and confidence for working towards human rights, and open questions. Numbers of rights listed, knowledge scores and confidence scores were calculated. Responses to the open questions were thematically analysed. After completing a human rights course, students had good knowledge and moderate confidence to work with human rights. Three themes were identified including 'learning about human rights', 'learning about structural, societal and global perspectives on occupational engagement' and 'learning how occupational therapists can work with groups, communities and populations: becoming articulate and empowered'. Human rights education fosters the development of occupational therapists who are skilled, knowledgeable, confident and empowered to address occupational injustices, according to these research findings. To develop a more occupationally just global society, education that considers iniquitous social structures and human rights is necessary. © 2016 Occupational Therapy Australia.

The Lavender Ceiling atop the Global Closet: Human Resource Development and Lesbian Expatriates

ERIC Educational Resources Information Center

Gedro, Julie

2010-01-01

This literature review will examine international assignments as career development opportunities and uncover multiple issues and considerations with respect to lesbians and international assignments. There is a clear interest in the fields of management and human resource management in the privileges, challenges, and opportunities of…

World Development Report, 1980. Part I: Adjustment and Growth in the 1980s. Part II: Poverty and Human Development. Annex: World Development Indicators. With Summary.

ERIC Educational Resources Information Center

Isenman, Paul; And Others

The report, third in a series of annual publications, examines some of the difficulties and prospects in areas of social and economic progress and human development which developing countries face during the next decade. Distinguishing oil-importing from oil-exporting developing countries, the first part of the report presents global and regional…

Our changing planet: The FY 1993 US global change research program. A supplement to the US President's fiscal year 1993 budget

NASA Technical Reports Server (NTRS)

1992-01-01

An improved predictive understanding of the integrated Earth system, including human interactions, will provide direct benefits by anticipating and planning for possible impacts on commerce, agriculture, energy, resource utilization, human safety, and environmental quality. The central goal of the U.S. Global Change Research Program (USGCRP) is to help establish the scientific understanding and the basis for national and international policymaking related to natural and human-induced changes in the global Earth system. This will be accomplished through: (1) establishing an integrated, comprehensive, long-term program of documenting the Earth system on a global scale; (2) conducting a program of focused studies to improve our understanding of the physical, geological, chemical, biological, and social processes that influence the Earth system processes; and (3) developing integrated conceptual and predictive Earth system models.

Improving global health: counting reasons why.

PubMed

Selgelid, Michael J

2008-08-01

This paper examines cumulative ethical and self-interested reasons why wealthy developed nations should be motivated to do more to improve health care in developing countries. Egalitarian and human rights reasons why wealthy nations should do more to improve global health are that doing so would (1) promote equality of opportunity (2) improve the situation of the worst-off, (3) promote respect of the human right to have one's most basic needs met, and (4) reduce undeserved inequalities in well-being. Utilitarian reasons for improving global health are that this would (5) promote the greater good of humankind, and (6) achieve enormous benefits while requiring only small sacrifices. Libertarian reasons are that this would (7) amend historical injustices and (8) meet the obligation to amend injustices that developed world countries have contributed to. Self-interested reasons why wealthy nations should do more to improve global health are that doing so would (9) reduce the threat of infectious diseases to developed countries, (10) promote developed countries' economic interests, and (11) promote global security. All of these reasons count, and together they add up to make an overwhelmingly powerful case for change. Those opposed to wealthy government funding of developing world health improvement would most likely appeal, implicitly or explicitly to the idea that coercive taxation for redistributive purposes would violate the right of an individual to keep his hard-earned income. The idea that this reason not to improve global health should outweigh the combination of rights and values embodied in the eleven reasons enumerated above, however is implausibly extreme, morally repugnant and perhaps imprudent.

Germany's expanding role in global health.

PubMed

Kickbusch, Ilona; Franz, Christian; Holzscheiter, Anna; Hunger, Iris; Jahn, Albrecht; Köhler, Carsten; Razum, Oliver; Schmidt, Jean-Olivier

2017-08-26

Germany has become a visible actor in global health in the past 10 years. In this Series paper, we describe how this development complements a broad change in perspective in German foreign policy. Catalysts for this shift have been strong governmental leadership, opportunities through G7 and G20 presidencies, and Germany's involvement in managing the Ebola virus disease outbreak. German global health engagement has four main characteristics that are congruent with the health agenda of the Sustainable Development Goals; it is rooted in human rights, multilateralism, the Bismarck model of social protection, and a link between development and investment on the basis of its own development trajectory after World War 2. The combination of momentum and specific characteristics makes Germany well equipped to become a leader in global health, yet the country needs to accept additional financial responsibility for global health, expand its domestic global health competencies, reduce fragmentation of global health policy making, and solve major incoherencies in its policies both nationally and internationally. Copyright © 2017 Elsevier Ltd. All rights reserved.

Conceptualizing a Human Right to Prevention in Global HIV/AIDS Policy

PubMed Central

Meier, Benjamin Mason; Brugh, Kristen Nichole; Halima, Yasmin

2012-01-01

Given current constraints on universal treatment campaigns, recent advances in public health prevention initiatives have revitalized efforts to stem the tide of HIV transmission. Yet, despite a growing imperative for prevention—supported by the promise of behavioral, structural and biomedical approaches to lower the incidence of HIV—human rights frameworks remain limited in addressing collective prevention policy through global health governance. Assessing the evolution of rights-based approaches to global HIV/AIDS policy, this review finds that human rights have shifted from collective public health to individual treatment access. While the advent of the HIV/AIDS pandemic gave meaning to rights in framing global health policy, the application of rights in treatment access litigation came at the expense of public health prevention efforts. Where the human rights framework remains limited to individual rights enforced against a state duty bearer, such rights have faced constrained application in framing population-level policy to realize the public good of HIV prevention. Concluding that human rights frameworks must be developed to reflect the complementarity of individual treatment and collective prevention, this article conceptualizes collective rights to public health, structuring collective combination prevention to alleviate limitations on individual rights frameworks and frame rights-based global HIV/AIDS policy to assure research expansion, prevention access and health system integration. PMID:23226723

Global variance in female population height: the influence of education, income, human development, life expectancy, mortality and gender inequality in 96 nations.

PubMed

Mark, Quentin J

2014-01-01

Human height is a heritable trait that is known to be influenced by environmental factors and general standard of living. Individual and population stature is correlated with health, education and economic achievement. Strong sexual selection pressures for stature have been observed in multiple diverse populations, however; there is significant global variance in gender equality and prohibitions on female mate selection. This paper explores the contribution of general standard of living and gender inequality to the variance in global female population heights. Female population heights of 96 nations were culled from previously published sources and public access databases. Factor analysis with United Nations international data on education rates, life expectancy, incomes, maternal and childhood mortality rates, ratios of gender participation in education and politics, the Human Development Index (HDI) and the Gender Inequality Index (GII) was run. Results indicate that population heights vary more closely with gender inequality than with population health, income or education.

Linked Open Data in the Global Change Information System (GCIS)

NASA Technical Reports Server (NTRS)

Tilmes, Curt A.

2012-01-01

The U.S. Global Change Research Program (http://globalchange.gov) coordinates and integrates federal research on changes in the global environment and their implications for society. The USGCRP is developing a Global Change Information System (GCIS) that will centralize access to data and information related to global change across the U.S. federal government. The first implementation will focus on the 2013 National Climate Assessment (NCA) . (http://assessment.globalchange.gov) The NCA integrates, evaluates, and interprets the findings of the USGCRP; analyzes the effects of global change on the natural environment, agriculture, energy production and use, land and water resources, transportation, human health and welfare, human social systems, and biological diversity; and analyzes current trends in global change, both human-induced and natural, and projects major trends for the subsequent 25 to 100 years. The NCA has received over 500 distinct technical inputs to the process, many of which are reports distilling and synthesizing even more information, coming from thousands of individuals around the federal, state and local governments, academic institutions and non-governmental organizations. The GCIS will present a web-based version of the NCA including annotations linking the findings and content of the NCA with the scientific research, datasets, models, observations, etc. that led to its conclusions. It will use semantic tagging and a linked data approach, assigning globally unique, persistent, resolvable identifiers to all of the related entities and capturing and presenting the relationships between them, both internally and referencing out to other linked data sources and back to agency data centers. The developing W3C PROV Data Model and ontology will be used to capture the provenance trail and present it in both human readable web pages and machine readable formats such as RDF and SPARQL. This will improve visibility into the assessment process, increase understanding and reproducibility, and ultimately increase credibility and trust of the resulting report. Building on the foundation of the NCA, longer term plans for the GCIS include extending these capabilities throughout the U.S. Global Change Research Program, centralizing access to global change data and information across the thirteen agencies that comprise the program.

Education and human survival: The relevance of the global security framework to international education

NASA Astrophysics Data System (ADS)

Williams, Christopher

2000-07-01

The nature of international education as a field of studies has been affected by global changes over the past decade. At the same time, the concept of global security has emerged, bringing together studies related to development, the environment and the understanding of violence. Although much of the education literature reflects the global security approach, it is not a field that has been subjected to much analysis as a whole. This paper provides an assessment of international education as a discipline, and outlines the global security framework. It examines how this framework is reflected in the forms of analysis used by international educationists. Finally it suggests how the central purpose of global security, namely ensuring human survival, could be adopted within international education to provide a clear sense of direction. This has specific implications for such areas as curriculum, assessment, educational provision and planning.

Education for Sustainable Development in Higher Education: State-of-the-Art, Barriers and Challenges

ERIC Educational Resources Information Center

Fernández-Sánchez, Gonzalo; Bernaldo, María Olga; Castillejo, Ana; Manzanero, Ana María

2014-01-01

Education for Sustainable Development (ESD) is a new educational paradigm that allows Universities to lead and respond to social needs towards a more sustainable life. The ESD is a global preparedness and complex phenomena in relation to the effects of human activity on the environment, society and economy in spatial (global, regional and local)…

Quantification of the epitope diversity of HIV-1-specific binding antibodies by peptide microarrays for global HIV-1 vaccine development

DOE PAGES

Stephenson, Kathryn E.; Neubauer, George H.; Reimer, Ulf; ...

2014-11-14

An effective vaccine against human immunodeficiency virus type 1 (HIV-1) will have to provide protection against a vast array of different HIV-1 strains. Current methods to measure HIV-1-specific binding antibodies following immunization typically focus on determining the magnitude of antibody responses, but the epitope diversity of antibody responses has remained largely unexplored. Here we describe the development of a global HIV-1 peptide microarray that contains 6564 peptides from across the HIV-1 proteome and covers the majority of HIV-1 sequences in the Los Alamos National Laboratory global HIV-1 sequence database. Using this microarray, we quantified the magnitude, breadth, and depth ofmore » IgG binding to linear HIV-1 sequences in HIV-1-infected humans and HIV-1-vaccinated humans, rhesus monkeys and guinea pigs. The microarray measured potentially important differences in antibody epitope diversity, particularly regarding the depth of epitope variants recognized at each binding site. Our data suggest that the global HIV-1 peptide microarray may be a useful tool for both preclinical and clinical HIV-1 research.« less

Quantification of the epitope diversity of HIV-1-specific binding antibodies by peptide microarrays for global HIV-1 vaccine development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stephenson, Kathryn E.; Neubauer, George H.; Reimer, Ulf

An effective vaccine against human immunodeficiency virus type 1 (HIV-1) will have to provide protection against a vast array of different HIV-1 strains. Current methods to measure HIV-1-specific binding antibodies following immunization typically focus on determining the magnitude of antibody responses, but the epitope diversity of antibody responses has remained largely unexplored. Here we describe the development of a global HIV-1 peptide microarray that contains 6564 peptides from across the HIV-1 proteome and covers the majority of HIV-1 sequences in the Los Alamos National Laboratory global HIV-1 sequence database. Using this microarray, we quantified the magnitude, breadth, and depth ofmore » IgG binding to linear HIV-1 sequences in HIV-1-infected humans and HIV-1-vaccinated humans, rhesus monkeys and guinea pigs. The microarray measured potentially important differences in antibody epitope diversity, particularly regarding the depth of epitope variants recognized at each binding site. Our data suggest that the global HIV-1 peptide microarray may be a useful tool for both preclinical and clinical HIV-1 research.« less

The Globalization of Racism

ERIC Educational Resources Information Center

Macedo, Donaldo; Gounari, Panayota

2005-01-01

Addressing ethnic cleansing, culture wars, human sufferings, terrorism, immigration, and intensified xenophobia, "Globalization of Racism" explains why it is vital that we gain a nuanced understanding of how ideology underlies all social, cultural, and political discourse and racist actions. The book looks at recent developments in…

Reflections on the ethics of recruiting foreign-trained human resources for health

PubMed Central

2011-01-01

Background Developed countries' gains in health human resources (HHR) from developing countries with significantly lower ratios of health workers have raised questions about the ethics or fairness of recruitment from such countries. By attracting and/or facilitating migration for foreign-trained HHR, notably those from poorer, less well-resourced nations, recruitment practices and policies may be compromising the ability of developing countries to meet the health care needs of their own populations. Little is known, however, about actual recruitment practices. In this study we focus on Canada (a country with a long reliance on internationally trained HHR) and recruiters working for Canadian health authorities. Methods We conducted interviews with health human resources recruiters employed by Canadian health authorities to describe their recruitment practices and perspectives and to determine whether and how they reflect ethical considerations. Results and discussion We describe the methods that recruiters used to recruit foreign-trained health professionals and the systemic challenges and policies that form the working context for recruiters and recruits. HHR recruiters' reflections on the global flow of health workers from poorer to richer countries mirror much of the content of global-level discourse with regard to HHR recruitment. A predominant market discourse related to shortages of HHR outweighed discussions of human rights and ethical approaches to recruitment policy and action that consider global health impacts. Conclusions We suggest that the concept of corporate social responsibility may provide a useful approach at the local organizational level for developing policies on ethical recruitment. Such local policies and subsequent practices may inform public debate on the health equity implications of the HHR flows from poorer to richer countries inherent in the global health worker labour market, which in turn could influence political choices at all government and health system levels. PMID:21251293

Reflections on the ethics of recruiting foreign-trained human resources for health.

PubMed

Runnels, Vivien; Labonté, Ronald; Packer, Corinne

2011-01-20

Developed countries' gains in health human resources (HHR) from developing countries with significantly lower ratios of health workers have raised questions about the ethics or fairness of recruitment from such countries. By attracting and/or facilitating migration for foreign-trained HHR, notably those from poorer, less well-resourced nations, recruitment practices and policies may be compromising the ability of developing countries to meet the health care needs of their own populations. Little is known, however, about actual recruitment practices. In this study we focus on Canada (a country with a long reliance on internationally trained HHR) and recruiters working for Canadian health authorities. We conducted interviews with health human resources recruiters employed by Canadian health authorities to describe their recruitment practices and perspectives and to determine whether and how they reflect ethical considerations. We describe the methods that recruiters used to recruit foreign-trained health professionals and the systemic challenges and policies that form the working context for recruiters and recruits. HHR recruiters' reflections on the global flow of health workers from poorer to richer countries mirror much of the content of global-level discourse with regard to HHR recruitment. A predominant market discourse related to shortages of HHR outweighed discussions of human rights and ethical approaches to recruitment policy and action that consider global health impacts. We suggest that the concept of corporate social responsibility may provide a useful approach at the local organizational level for developing policies on ethical recruitment. Such local policies and subsequent practices may inform public debate on the health equity implications of the HHR flows from poorer to richer countries inherent in the global health worker labour market, which in turn could influence political choices at all government and health system levels.

The influence of globalization on medical regulation: a descriptive analysis of international medical graduates registered through alternative licensure routes in Ontario.

PubMed

Yen, Wendy; Hodwitz, Kathryn; Thakkar, Niels; Martimianakis, Maria Athina Tina; Faulkner, Dan

2016-12-01

The increasing globalization of the medical profession has influenced health policy, health human resource planning, and medical regulation in Canada. Since the early 2000s, numerous policy initiatives have been created to facilitate the entry of international medical graduates (IMGs) into the Canadian workforce. In Ontario, the College of Physicians and Surgeons of Ontario (CPSO) developed alternative licensure routes to increase the ability of qualified IMGs to obtain licenses to practice. The current study provides demographic and descriptive information about the IMGs registered through the CPSO's alternative licensure routes between 2000 and 2012. An analysis of the characteristics and career trajectories of all IMGs practicing in the province sheds light on broader globalization trends and raises questions about the future of health human resource planning in Canada. As the medical profession becomes increasingly globalized, health policy and regulation will continue to be influenced by trends in international migration, concerns about global health equity, and the shifting demographics of the Canadian physician workforce. Implications for future policy development in the complex landscape of medical education and practice are discussed.

The Earth's Population Can Reach 14 Billion in the 23rd Century without Significant Adverse Effects on Survivability.

PubMed

Krapivin, Vladimir F; Varotsos, Costas A; Soldatov, Vladimir Yu

2017-08-07

This paper presents the results obtained from the study of the sustainable state between nature and human society on a global scale, focusing on the most critical interactions between the natural and anthropogenic processes. Apart from the conventional global models, the basic tool employed herein is the newly proposed complex model entitled "nature-society system (NSS) model", through which a reliable modeling of the processes taking place in the global climate-nature-society system (CNSS) is achieved. This universal tool is mainly based on the information technology that allows the adaptive conformance of the parametric and functional space of this model. The structure of this model includes the global biogeochemical cycles, the hydrological cycle, the demographic processes and a simple climate model. In this model, the survivability indicator is used as a criterion for the survival of humanity, which defines a trend in the dynamics of the total biomass of the biosphere, taking into account the trends of the biocomplexity dynamics of the land and hydrosphere ecosystems. It should be stressed that there are no other complex global models comparable to those of the CNSS model developed here. The potential of this global model is demonstrated through specific examples in which the classification of the terrestrial ecosystem is accomplished by separating 30 soil-plant formations for geographic pixels 4° × 5°. In addition, humanity is considered to be represented by three groups of economic development status (high, transition, developing) and the World Ocean is parameterized by three latitude zones (low, middle, high). The modelling results obtained show the dynamics of the CNSS at the beginning of the 23rd century, according to which the world population can reach the level of 14 billion without the occurrence of major negative impacts.

Can the global carbon budget be balanced?

USGS Publications Warehouse

Markewich, Helaine W.; Bliss, Norman B.; Stallard, Robert F.; Sundquist, Eric T.

1997-01-01

The Mississippi Basin Carbon Project of the U.S. Geological Survey (USGS) is an effort to examine interactions between the global carbon cycle and human-induced changes to the land surface, such as farming and urbanization. Investigations in the Mississippi River basin will provide the data needed for calculating the global significance of land-use changes on land-based carbon cycling. These data are essential for predicting and mitigating the effects of global environmental change.The Mississippi Basin Carbon Project is focused on the third largest river system in the world. The Mississippi River and its tributaries drain more than 40% of the conterminous United States. The basin includes areas that typify vast regions of the Earth's surface that have undergone human development.

Cultures of Funding, Management and Learning in the Global Mainstream

ERIC Educational Resources Information Center

Preston, R.

2005-01-01

This paper examines changes over the last 20 years which have shaped international human development assistance for the alleviation of poverty and inclusion and what it achieves. With reference to labour market restructuring and the contemporary rhetoric, design and management of human development interventions, it describes a study into how these…

Reconnecting to the biosphere.

PubMed

Folke, Carl; Jansson, Asa; Rockström, Johan; Olsson, Per; Carpenter, Stephen R; Chapin, F Stuart; Crépin, Anne-Sophie; Daily, Gretchen; Danell, Kjell; Ebbesson, Jonas; Elmqvist, Thomas; Galaz, Victor; Moberg, Fredrik; Nilsson, Måns; Osterblom, Henrik; Ostrom, Elinor; Persson, Asa; Peterson, Garry; Polasky, Stephen; Steffen, Will; Walker, Brian; Westley, Frances

2011-11-01

Humanity has emerged as a major force in the operation of the biosphere, with a significant imprint on the Earth System, challenging social-ecological resilience. This new situation calls for a fundamental shift in perspectives, world views, and institutions. Human development and progress must be reconnected to the capacity of the biosphere and essential ecosystem services to be sustained. Governance challenges include a highly interconnected and faster world, cascading social-ecological interactions and planetary boundaries that create vulnerabilities but also opportunities for social-ecological change and transformation. Tipping points and thresholds highlight the importance of understanding and managing resilience. New modes of flexible governance are emerging. A central challenge is to reconnect these efforts to the changing preconditions for societal development as active stewards of the Earth System. We suggest that the Millennium Development Goals need to be reframed in such a planetary stewardship context combined with a call for a new social contract on global sustainability. The ongoing mind shift in human relations with Earth and its boundaries provides exciting opportunities for societal development in collaboration with the biosphere--a global sustainability agenda for humanity.

Impact of human Campylobacter infections in Southeast Asia: The contribution of the poultry sector.

PubMed

Premarathne, Jayasekara Mudiyanselage Krishanthi Jayarukshi Kumari; Satharasinghe, Dilan Amila; Huat, John Tang Yew; Basri, Dayang Fredalina; Rukayadi, Yaya; Nakaguchi, Yoshitsugu; Nishibuchi, Mitsuaki; Radu, Son

2017-12-12

Campylobacter is globally recognized as a major cause of foodborne infection in humans, whilst the development of antimicrobial resistance and the possibility of repelling therapy increase the threat to public health. Poultry is the most frequent source of Campylobacter infection in humans, and southeast Asia is a global leader in poultry production, consumption, and exports. Though three of the world's top 20 most populated countries are located in southeast Asia, the true burden of Campylobacter infection in the region has not been fully elucidated. Based on published data, Campylobacter has been reported in humans, animals, and food commodities in the region. To our knowledge, this study is the first to review the status of human Campylobacter infection in southeast Asia and to discuss future perspectives. Gaining insight into the true burden of the infection and prevalence levels of Campylobacter spp. in the southeast Asian region is essential to ensuring global and regional food safety through facilitating improvements in surveillance systems, food safety regulations, and mitigation strategies.

Modeling Physiological Systems in the Human Body as Networks of Quasi-1D Fluid Flows

NASA Astrophysics Data System (ADS)

Staples, Anne

2008-11-01

Extensive research has been done on modeling human physiology. Most of this work has been aimed at developing detailed, three-dimensional models of specific components of physiological systems, such as a cell, a vein, a molecule, or a heart valve. While efforts such as these are invaluable to our understanding of human biology, if we were to construct a global model of human physiology with this level of detail, computing even a nanosecond in this computational being's life would certainly be prohibitively expensive. With this in mind, we derive the Pulsed Flow Equations, a set of coupled one-dimensional partial differential equations, specifically designed to capture two-dimensional viscous, transport, and other effects, and aimed at providing accurate and fast-to-compute global models for physiological systems represented as networks of quasi one-dimensional fluid flows. Our goal is to be able to perform faster-than-real time simulations of global processes in the human body on desktop computers.

DEVELOPING A HUMAN RIGHTS-BASED PROGRAM FOR TUBERCULOSIS CONTROL IN GEORGIAN PRISONS

PubMed Central

Gegia, Medea; Kalandadze, Iagor; Madzgharashvili, Mikheil; Furin, Jennifer

2013-01-01

Tuberculosis (TB) is one of the leading infectious killers of adults globally. Incarcerated individuals represent a vulnerable population when it comes to TB exposure, development of disease, and poor treatment outcomes. The TB pandemic in prisons is a serious human rights issue, and multiple global organizations have called for human rights-based strategies to address it. There are, however, few countries implementing such programs on the ground. Georgia, a former Soviet republic located in the Caucasus Mountains, has high rates of TB and a large prison population. This paper describes a needs assessment carried out in one prison in Georgia and the human rights-based strategy being implemented by the Georgian National TB Program to address TB control in the prison setting. It is hoped that the proposed program can serve as a model for other countries with high rates of TB among incarcerated individuals. PMID:22773034

A Cross-Cultural Investigation of Human Performance Technology Interventions

ERIC Educational Resources Information Center

Vadivelu, Ramaswamy N.

2010-01-01

Human Performance Technology (HPT) is a field of practice that has evolved from advancements in organizational development, instructional design, strategic human resource management and cognitive psychology. As globalization and trends like outsourcing and off-shoring start to dominate the way organizations grow, HPT practitioners are managing the…

Human-ignited wildfire patterns and responses to policy shifts

Treesearch

M. L. Chas-Amil; J. P. Prestemon; C. J. McClean; J. Touza

2015-01-01

Development of efficient forest wildfire policies requires an understanding of the underlying reasons behind forest fire occurrences. Globally, there is a close relationship between forest wildfires and human activities; most wildfires are human events due to negligence (e.g., agricultural burning escapes) and deliberate actions (e.g., vandalism, pyromania, revenge,...

Sustainability, synthetic chemicals, and human exposure.

PubMed

Podein, Rian J; Hernke, Michael T; Fortney, Luke W; Rakel, David P

2010-01-01

Public concerns regarding exposures to synthetic chemicals are increasing. Globally, there are increasing concentrations of many synthetic chemicals within the environment. The ubiquitous extent of some chemicals makes human exposure unavoidable. Biomonitoring has emerged as the optimal method for assessing exposures. The extent of human exposure and contamination occurs throughout the life cycle and is widespread. Although there is limited information on health risks for the majority of chemicals within our environment, and those identified with biomonitoring, many are known or suspected to cause human harm. Continued global and national unsustainable development regarding synthetic chemicals will increase the extent of environmental and human contamination unless precautionary action is implemented. Precautionary legislation may protect ecological and public health until societal sustainability is achieved.

Human Health in the Balance. Hands-On! Developing Active Learning Modules on the Human Dimensions of Global Change.

ERIC Educational Resources Information Center

Meade, Melinda S.; Washburn, Sarah; Holman, Jeremy T.

This learning module aims to engage students in problem solving, critical thinking, scientific inquiry, and cooperative learning. The module is appropriate for use in any introductory or intermediate undergraduate course that focuses on human-environment relationships. The module states that human health is a product of complex interactions among…

Impacts of Climate Change on Human Health in the United ...

EPA Pesticide Factsheets

Climate change threatens human health and well-being in the United States. To address this growing threat, the Interagency Group on Climate Change and Human Health (CCHHG), a working group of the U.S. Global Change Research Program’s (USGCRP), has developed this assessment as part of the ongoing efforts of the USGCRP’s National Climate Assessment (NCA) and as called for under the President’s Climate Action Plan. The authors of this assessment have compiled and assessed current research on human health impacts of climate change and summarized the current “state of the science” for a number of key impact areas. This assessment provides a comprehensive update to the most recent detailed technical assessment for the health impacts of climate change, 2008 Synthesis and Assessment Product 4.6 (SAP 4.6) Analyses of the Effects of Global Change on Human Health and Welfare and Human Systems (CCSP 2008). It also updates and builds upon the health chapter of the third NCA (Melillo et al. 2014). The lead and coordinating Federal agencies for the USGCRP Climate and Health Assessment are the Centers for Disease Control and Prevention (CDC), Environmental Protection Agency (EPA), National Institute of Health (NIH), and National Oceanic and Atmospheric Administration (NOAA). Available at https://health2016.globalchange.gov/ The interagency U.S. Global Change Research Program (USGCRP) has developed this assessment as part of the ongoing efforts of their National C

Energy. Our Common Home: Earth. A Curriculum Strategy to Affect Student Skills Development and Exposure to Diverse Global Natural/Social Environments.

ERIC Educational Resources Information Center

Peters, Richard

One of a series of global education instructional units, this energy awareness curriculum was designed to be infused with existing social studies courses aimed at students in grades 5-12. Concept-based and skills-oriented, the curriculum provides opportunities for students to develop an understanding of synthetic energy sources; human dependence…

Under the (legal) radar screen: global health initiatives and international human rights obligations

PubMed Central

2012-01-01

Background Given that many low income countries are heavily reliant on external assistance to fund their health sectors the acceptance of obligations of international assistance and cooperation with regard to the right to health (global health obligations) is insufficiently understood and studied by international health and human rights scholars. Over the past decade Global Health Initiatives, like the Global Fund to fight AIDS, Tuberculosis and Malaria (Global Fund) have adopted novel approaches to engaging with stakeholders in high and low income countries. This article explores how this experience impacted on acceptance of the international obligation to (help) fulfil the right to health beyond borders. Methods The authors conducted an extensive review of international human rights law literature, transnational legal process literature, global public health literature and grey literature pertaining to Global Health Initiatives. To complement this desk work and deepen their understanding of how and why different legal norms evolve the authors conducted 19 in-depth key informant interviews with actors engaged with three stakeholders; the European Union, the United States and Belgium. The authors then analysed the interviews through a transnational legal process lens. Results Through according value to the process of examining how and why different legal norms evolve transnational legal process offers us a tool for engaging with the dynamism of developments in global health suggesting that operationalising global health obligations could advance the right to health for all. Conclusions In many low-income countries the health sector is heavily dependent on external assistance to fulfil the right to health of people thus it is vital that policies and tools for delivering reliable, long-term assistance are developed so that the right to health for all becomes more than a dream. Our research suggests that the Global Fund experience offers lessons to build on. PMID:23153090

The importance of human resources management in health care: a global context.

PubMed

Kabene, Stefane M; Orchard, Carole; Howard, John M; Soriano, Mark A; Leduc, Raymond

2006-07-27

This paper addresses the health care system from a global perspective and the importance of human resources management (HRM) in improving overall patient health outcomes and delivery of health care services. We explored the published literature and collected data through secondary sources. Various key success factors emerge that clearly affect health care practices and human resources management. This paper will reveal how human resources management is essential to any health care system and how it can improve health care models. Challenges in the health care systems in Canada, the United States of America and various developing countries are examined, with suggestions for ways to overcome these problems through the proper implementation of human resources management practices. Comparing and contrasting selected countries allowed a deeper understanding of the practical and crucial role of human resources management in health care. Proper management of human resources is critical in providing a high quality of health care. A refocus on human resources management in health care and more research are needed to develop new policies. Effective human resources management strategies are greatly needed to achieve better outcomes from and access to health care around the world.

The importance of human resources management in health care: a global context

PubMed Central

Kabene, Stefane M; Orchard, Carole; Howard, John M; Soriano, Mark A; Leduc, Raymond

2006-01-01

Background This paper addresses the health care system from a global perspective and the importance of human resources management (HRM) in improving overall patient health outcomes and delivery of health care services. Methods We explored the published literature and collected data through secondary sources. Results Various key success factors emerge that clearly affect health care practices and human resources management. This paper will reveal how human resources management is essential to any health care system and how it can improve health care models. Challenges in the health care systems in Canada, the United States of America and various developing countries are examined, with suggestions for ways to overcome these problems through the proper implementation of human resources management practices. Comparing and contrasting selected countries allowed a deeper understanding of the practical and crucial role of human resources management in health care. Conclusion Proper management of human resources is critical in providing a high quality of health care. A refocus on human resources management in health care and more research are needed to develop new policies. Effective human resources management strategies are greatly needed to achieve better outcomes from and access to health care around the world. PMID:16872531

The post-millennium development goals agenda: include 'end to all wars' as a public health goal!

PubMed

Jayasinghe, Saroj

2014-09-01

The process of identifying global post-millennium development goals (post-MDGs) has begun in earnest. Consensus is emerging in certain areas (e.g. eliminating poverty) and conflicts and violence are recognized as key factors that retard human development. However, current discussions focus on tackling intra-state conflicts and individual-based violence and hardly mention eliminating wars as a goal. Wars create public health catastrophes. They kill, maim, displace and affect millions. Inter-state wars fuel intra-state conflicts and violence. The peace agenda should not be the monopoly of the UN Security Council, and the current consensus-building process setting the post-MDG agenda is a rallying point for the global community. The human rights approach will not suffice to eliminate wars, because few are fought to protect human rights. The development agenda should therefore commit to eliminating all wars by 2030. Targets to reduce tensions and discourage wars should be included. We should act now. © The Author(s) 2014.

Working to Educate Global Citizens and Create Neighborly Communities Locally and Globally: Penn's Partnerships in West Philadelphia as a Democratic Experiment in Progress

ERIC Educational Resources Information Center

Harkavy, Ira; Hartley, Matthew; Hodges, Rita Axelroth; Weeks, Joann

2016-01-01

In the rapidly accelerating global era in which we now live, human beings must solve a vast array of unprecedently complex problems. Given their proclaimed dedication to critical intelligence, and their unique constellation of formidable resources to develop it, institutions of higher education have a unique responsibility to help solve these…

Megafauna biomass tradeoff as a driver of Quaternary and future extinctions

PubMed Central

Barnosky, Anthony D.

2008-01-01

Earth's most recent major extinction episode, the Quaternary Megafauna Extinction, claimed two-thirds of mammal genera and one-half of species that weighed >44 kg between ≈50,000 and 3,000 years ago. Estimates of megafauna biomass (including humans as a megafauna species) for before, during, and after the extinction episode suggest that growth of human biomass largely matched the loss of non-human megafauna biomass until ≈12,000 years ago. Then, total megafauna biomass crashed, because many non-human megafauna species suddenly disappeared, whereas human biomass continued to rise. After the crash, the global ecosystem gradually recovered into a new state where megafauna biomass was concentrated around one species, humans, instead of being distributed across many species. Precrash biomass levels were finally reached just before the Industrial Revolution began, then skyrocketed above the precrash baseline as humans augmented the energy available to the global ecosystem by mining fossil fuels. Implications include (i) an increase in human biomass (with attendant hunting and other impacts) intersected with climate change to cause the Quaternary Megafauna Extinction and an ecological threshold event, after which humans became dominant in the global ecosystem; (ii) with continued growth of human biomass and today's unprecedented global warming, only extraordinary and stepped-up conservation efforts will prevent a new round of extinctions in most body-size and taxonomic spectra; and (iii) a near-future biomass crash that will unfavorably impact humans and their domesticates and other species is unavoidable unless alternative energy sources are developed to replace dwindling supplies of fossil fuels. PMID:18695222

Suicide rate in relation to the Human Development Index and other health related factors: A global ecological study from 91 countries.

PubMed

Khazaei, Salman; Armanmehr, Vajihe; Nematollahi, Shahrzad; Rezaeian, Shahab; Khazaei, Somayeh

2017-06-01

There has been no worldwide ecological study on suicide as a global major public health problem. This study aimed to identify the variations in suicide specific rates using the Human Development Index (HDI) and some health related variables among countries around the world. In this ecological study, we obtained the data from the World Bank Report 2013. The analysis was restricted to 91 countries for which both the epidemiologic data from the suicide rates and HDI were available. Overall, the global prevalence of suicide rate was 10.5 (95% confidence intervals: 8.8, 12.2) per 100,000 individuals, which significantly varied according to gender (16.3 in males vs. 4.6 in females, p<0.001) and different levels of human development (11.64/100,000 individuals in very high development countries, 7.93/100,000 individuals in medium development countries, and 13.94/100,000 individuals in high development countries, p=0.004). In conclusion, the suicide rate varies greatly between countries with different development levels. Our findings also suggest that male gender and HDI components are associated with an increased risk of suicide behaviors. Hence, detecting population subgroups with a high suicide risk and reducing the inequality of socioeconomic determinants are necessary to prevent this disorder around the world. Copyright © 2017 Ministry of Health, Saudi Arabia. Published by Elsevier Ltd. All rights reserved.

A Framework for a Multi-State Human Capital Development Data System

ERIC Educational Resources Information Center

Prescott, Brian T.; Ewell, Peter

2009-01-01

The rise of a globalized knowledge economy requires nations to understand the distribution of skills and abilities in their populations. It is no longer sufficient to know how many resources are devoted to the development of nations' human capital. Today, nations also must be able to demonstrate and understand the outcomes of their educational…

HRD Trends Worldwide: Shared Solutions To Compete in a Global Economy. Improving Human Performance Series.

ERIC Educational Resources Information Center

Phillips, Jack J.

This book, which is intended for individuals involved in developing, delivering, and supporting human resource development (HRD) programs, discusses worldwide HRD trends that were identified in a study of the HRD practices in 35 countries. Chapter 1 discusses the importance of the HRD trends identified and explains how they were identified.…

Promoting the Reading Culture Towards Human Capital and Global Development

ERIC Educational Resources Information Center

Olasehinde, M. O.; Akanmode, O. A.; Alaiyemola, A. T.; Babatunde, O. T.

2015-01-01

It is commonly agreed that a country cannot be fully developed without large-scale investment in her educational scheme since the breakthrough of a country is directly proportional to her educational level. Since the acquisition of effective reading skills has a positive effect on all school subjects, then reading is sine-qua-non for human capital…

In Utero Bisphenol A Concentration, Metabolism, and Global DNA Methylation Across Matched Placenta, Kidney, and Liver in the Human Fetus

PubMed Central

Nahar, Muna S.; Liao, Chunyang; Kannan, Kurunthachalam; Harris, Craig; Dolinoy, Dana C.

2014-01-01

While urine has been an easily accessible and feasible matrix for human biomonitoring, analytical measurements in internal tissues and organs can provide more accurate exposure assessments to understand disease etiology. This is especially important for the endocrine active compound, bisphenol A (BPA), where studies investigating internal doses at sensitive periods of human development are currently lacking. Herein, BPA concentrations, BPA-specific metabolizing enzyme gene expression, and global DNA methylation were characterized across three matched tissues from elective pregnancy terminations of 2nd trimester human fetuses: the placenta, liver, and kidney (N=12 each; N=36 total). Compared to liver (free: 0.54-50.5 ng/g), BPA concentrations were lower in matched placenta (<0.05-25.4 ng/g) and kidney (0.08-11.1 ng/g) specimens. BPA-specific metabolism gene expression of GUSB, UGT2B15, STS, and SULT1A1 differed across each tissue type; however, conjugation and deconjugation expression patterns were similar across the fetus. Average LINE1 and CCGG global methylation were 58.3 and 59.2% in placenta, 79.5 and 66.4% in fetal liver, and 77.9 and 77.0% in fetal kidney, with significant tissue-specific DNA methylation differences in both LINE1 (p-value <0.001) and CCGG content (p-value <0.001). Total BPA concentrations were positively associated with global methylation for the placenta only using the LINE1 assay (p-value: 0.002), suggesting organ-specific biological effects after fetal exposure. Utilizing sensitive human clinical specimens, results are informative for BPA toxicokinetics and toxicodynamics assessment in the developing human fetus. PMID:25434263

Development of Global Change Research in Developing Countries

NASA Astrophysics Data System (ADS)

Sierra, Carlos A.; Yepes, Adriana P.

2010-10-01

Ecosystems and Global Change in the Context of the Neotropics; Medellín, Colombia, 19-20 May 2010; Research in most areas of global environmental change is overwhelmingly produced outside developing countries, which are usually consumers rather than producers of the knowledge associated with their natural resources. While there have been important recent advances in understanding the causes of global-¬scale changes and their consequences to the functioning of tropical ecosystems, there is still an important gap in the understanding of these changes at regional and national levels (where important political decisions are usually made). A symposium was held with the aim of surveying the current state of research activities in a small, developing country such as Colombia. It was jointly organized by the Research Center on Ecosystems and Global Change, Carbono and Bosques; the National University of Colombia at Medellín and the Colombian Ministry of the Environment, Housing, and Regional Development. This 2-¬day symposium gathered Colombian and international scientists involved in different areas of global environmental change, tropical ecosystems, and human societies.

Global Education as a Way of Reinforcing the Process by Which a Solidaritous and Just World is Built

NASA Astrophysics Data System (ADS)

Kaniewska, Małgorzata; Klimski, Marcin

2017-12-01

Global education is a part of civic education and upbringing that contributes to their scope through the better understanding of various phenomena and global interdependencies that it affords. It thus represents a response to globalisation processes that has as its goal the development of critical thinking skills in schoolchildren from an early age, with a view to stereotypes and prejudices being combated, human life and human dignity being shown values, and emphasis placed on equality, peace, tolerance, solidarity and equity. The paper considers the reasons for including axiological reflection in school education programmes encompassing matters that are global in nature. Also presented are methods by which to achieve postulates of global education at the primary-school teaching level, as well as the results of research into the level of knowledge on key aspects of this education that are present among primary-school teachers.

Global assessment of human losses due to earthquakes

USGS Publications Warehouse

Silva, Vitor; Jaiswal, Kishor; Weatherill, Graeme; Crowley, Helen

2014-01-01

Current studies have demonstrated a sharp increase in human losses due to earthquakes. These alarming levels of casualties suggest the need for large-scale investment in seismic risk mitigation, which, in turn, requires an adequate understanding of the extent of the losses, and location of the most affected regions. Recent developments in global and uniform datasets such as instrumental and historical earthquake catalogues, population spatial distribution and country-based vulnerability functions, have opened an unprecedented possibility for a reliable assessment of earthquake consequences at a global scale. In this study, a uniform probabilistic seismic hazard assessment (PSHA) model was employed to derive a set of global seismic hazard curves, using the open-source software OpenQuake for seismic hazard and risk analysis. These results were combined with a collection of empirical fatality vulnerability functions and a population dataset to calculate average annual human losses at the country level. The results from this study highlight the regions/countries in the world with a higher seismic risk, and thus where risk reduction measures should be prioritized.

Sustainable intensification of agriculture for human prosperity and global sustainability.

PubMed

Rockström, Johan; Williams, John; Daily, Gretchen; Noble, Andrew; Matthews, Nathanial; Gordon, Line; Wetterstrand, Hanna; DeClerck, Fabrice; Shah, Mihir; Steduto, Pasquale; de Fraiture, Charlotte; Hatibu, Nuhu; Unver, Olcay; Bird, Jeremy; Sibanda, Lindiwe; Smith, Jimmy

2017-02-01

There is an ongoing debate on what constitutes sustainable intensification of agriculture (SIA). In this paper, we propose that a paradigm for sustainable intensification can be defined and translated into an operational framework for agricultural development. We argue that this paradigm must now be defined-at all scales-in the context of rapidly rising global environmental changes in the Anthropocene, while focusing on eradicating poverty and hunger and contributing to human wellbeing. The criteria and approach we propose, for a paradigm shift towards sustainable intensification of agriculture, integrates the dual and interdependent goals of using sustainable practices to meet rising human needs while contributing to resilience and sustainability of landscapes, the biosphere, and the Earth system. Both of these, in turn, are required to sustain the future viability of agriculture. This paradigm shift aims at repositioning world agriculture from its current role as the world's single largest driver of global environmental change, to becoming a key contributor of a global transition to a sustainable world within a safe operating space on Earth.

Using Population Data to Address the Human Dimensions of Environmental Change

Treesearch

D.M. Mageean; J.G. Bartlett

1999-01-01

In recent years researchers and policy makers have identified population-environment interactions as crucial to issues of ecology, economic development, and human welfare. It seems clear that human populations and demands on the environment are driving ecological change in such areas as global warming, ozone depletion, deforestation, biodiversity loss, land degradation...

Impacts of Climate Change on Human Health in the United States: A Scientific Assessment

EPA Science Inventory

Climate change threatens human health and well-being in the United States. To address this growing threat, the Interagency Group on Climate Change and Human Health (CCHHG), a working group of the U.S. Global Change Research Program’s (USGCRP), has developed this assessment as par...

Professionalizing a Global Social Movement: Universities and Human Rights

ERIC Educational Resources Information Center

Suarez, David; Bromley, Patricia

2012-01-01

Research on the human rights movement emphasizes direct changes in nation-states, focusing on the efficacy of treaties and the role of advocacy in mitigating immediate violations. However, more than 140 universities in 59 countries established academic chairs, research centers, and programs for human rights from 1968-2000, a development that…

The Impact of Globalization on Russian Education

ERIC Educational Resources Information Center

Sinagatullin Birsk, Ilghiz M.

2003-01-01

The notion of globalization, which Andrutchenko (2001) defines as a "consequence of the development of human civilization," and the way it is related to the issues of education are being discussed widely today among Russian educational and scientific circles, education policymakers, scholars, educators, as well as school and university…

Comprehending the Critical Importance of Vocational Technical Education in a Global Economy Era.

ERIC Educational Resources Information Center

Wolansky, William D.

1990-01-01

Industrialized nations have learned that vocational education is essential to developing a skilled work force. Newly industrialized countries competing in the global economy are finding that automation, multinational companies, and rapid growth are making investment in human resources through training a critical strategy. (SK)

Internationalization of Higher Education in Post-Soviet Small States: Realities and Perspectives of Moldova

ERIC Educational Resources Information Center

Kushnarenko, Valentyna; Cojocari, Ludmila

2012-01-01

Internationalization of higher education has become a priority for many universities in post-Soviet small states. Focusing on international communication networks, student mobility, or international curriculum development, universities invest human and financial resources to prepare graduates to meet global challenges. Globalization and…

Geoscience Education and Global Development

ERIC Educational Resources Information Center

Locke, Sharon; Libarkin, Julie; Chang, Chun-Yen

2012-01-01

A fundamental goal of geoscience education is ensuring that all inhabitants of the planet have knowledge of the natural processes that shape the physical environment, and understand how the actions of humans have an impact on the Earth on local, regional, and global scales. Geoscientists accept that deep understanding of natural processes requires…

Soil-transmitted helminthiases: implications of climate change and human behavior.

PubMed

Weaver, Haylee J; Hawdon, John M; Hoberg, Eric P

2010-12-01

Soil-transmitted helminthiases (STHs) collectively cause the highest global burden of parasitic disease after malaria and are most prevalent in the poorest communities, especially in sub-Saharan Africa. Climate change is predicted to alter the physical environment through cumulative impacts of warming and extreme fluctuations in temperature and precipitation, with cascading effects on human health and wellbeing, food security and socioeconomic infrastructure. Understanding how the spectrum of climate change effects will influence STHs is therefore of critical importance to the control of the global burden of human parasitic disease. Realistic progress in the global control of STH in a changing climate requires a multidisciplinary approach that includes the sciences (e.g. thermal thresholds for parasite development and resilience) and social sciences (e.g. behavior and implementation of education and sanitation programs). Copyright © 2010 Elsevier Ltd. All rights reserved.

The Global Emergency Observation and Warning System

NASA Technical Reports Server (NTRS)

Bukley, Angelia P.; Mulqueen, John A.

1994-01-01

Based on an extensive characterization of natural hazards, and an evaluation of their impacts on humanity, a set of functional technical requirements for a global warning and relief system was developed. Since no technological breakthroughs are required to implement a global system capable of performing the functions required to provide sufficient information for prevention, preparedness, warning, and relief from natural disaster effects, a system is proposed which would combine the elements of remote sensing, data processing, information distribution, and communications support on a global scale for disaster mitigation.

The human hookworm vaccine: recent updates and prospects for success.

PubMed

Bottazzi, M E

2015-09-01

Approximately 440 million people globally are afflicted by hookworm disease, one of the 17 WHO-recognized neglected tropical diseases (NTDs). The iron-deficiency anaemia attributed to this disease contributes to at least 3.2 million disability-adjusted life years (DALYs) according to the Global Burden of Disease Study 2010. The current WHO-recommended control strategies rely primarily on mass drug administration or preventive chemotherapy. However, evidence is starting to accumulate confirming that preventive chemotherapy alone will not be sufficient to reduce the reinfection rates of hookworm, especially in areas of heavy transmission. The global health and research community is currently building a consensus stressing the need for the advancement of research and innovation to bridge the gaps and identify new public health interventions for diseases such as hookworm and other NTDs. This paper presents the strategies used by the Sabin Vaccine Institute Product Development Partnership (Sabin PDP) in their ongoing endeavour for the development of a human hookworm vaccine. Recent updates and the current prospects for success of an effective human hookworm vaccine, as a new technology to be linked to or combined with drug interventions, are presented.

Globalisation and human dignity: the case of the information superhighway.

PubMed

Hamelink, C J

1996-01-01

In 1994, Vice President Al Gore coined the concept of the Information Superhighway during a speech in Buenos Aires in which he proposed the development of a global information infrastructure. The project envisions the incorporation of all existing communication networks into one system, facilitating the globalization of markets. The internet, a decentralized network of computer networks, is one small-scale, existing model of what the superhighway could be, a public space owned by nobody in which communication takes place largely for noncommercial purposes. The internet currently connects 40 million computer users from at least 90 countries. The alternative model for the superhighway is the privately managed global shopping mall, a global interactive marketplace for information, entertainment, and advertising. The author warns, however, that it is not possible to predict the future social impact of such an information superhighway. Decision makers nonetheless push ahead in development, full of confidence in the merit and infallibility of technology. Since one cannot accurately predict the future, it rational to assume that social consequences may both promote and threaten human dignity. The author explains at which level he believes the superhighway threatens the human rights norms of equality, inviolability, and liberty, and discusses what the World Association for Christian Communication can do.

Reviewing the History of Pandemic Influenza: Understanding Patterns of Emergence and Transmission

PubMed Central

Saunders-Hastings, Patrick R.; Krewski, Daniel

2016-01-01

For centuries, novel strains of influenza have emerged to produce human pandemics, causing widespread illness, death, and disruption. There have been four influenza pandemics in the past hundred years. During this time, globalization processes, alongside advances in medicine and epidemiology, have altered the way these pandemics are experienced. Drawing on international case studies, this paper provides a review of the impact of past influenza pandemics, while examining the evolution of our understanding of, and response to, these viruses. This review argues that pandemic influenza is in part a consequence of human development, and highlights the importance of considering outbreaks within the context of shifting global landscapes. While progress in infectious disease prevention, control, and treatment has improved our ability to respond to such outbreaks, globalization processes relating to human behaviour, demographics, and mobility have increased the threat of pandemic emergence and accelerated global disease transmission. Preparedness planning must continue to evolve to keep pace with this heightened risk. Herein, we look to the past for insights on the pandemic experience, underlining both progress and persisting challenges. However, given the uncertain timing and severity of future pandemics, we emphasize the need for flexible policies capable of responding to change as such emergencies develop. PMID:27929449

Emerging and Reemerging Neglected Tropical Diseases: a Review of Key Characteristics, Risk Factors, and the Policy and Innovation Environment

PubMed Central

Liang, Bryan A.; Cuomo, Raphael; Hafen, Ryan; Brouwer, Kimberly C.; Lee, Daniel E.

2014-01-01

SUMMARY In global health, critical challenges have arisen from infectious diseases, including the emergence and reemergence of old and new infectious diseases. Emergence and reemergence are accelerated by rapid human development, including numerous changes in demographics, populations, and the environment. This has also led to zoonoses in the changing human-animal ecosystem, which are impacted by a growing globalized society where pathogens do not recognize geopolitical borders. Within this context, neglected tropical infectious diseases have historically lacked adequate attention in international public health efforts, leading to insufficient prevention and treatment options. This subset of 17 infectious tropical diseases disproportionately impacts the world's poorest, represents a significant and underappreciated global disease burden, and is a major barrier to development efforts to alleviate poverty and improve human health. Neglected tropical diseases that are also categorized as emerging or reemerging infectious diseases are an even more serious threat and have not been adequately examined or discussed in terms of their unique risk characteristics. This review sets out to identify emerging and reemerging neglected tropical diseases and explore the policy and innovation environment that could hamper or enable control efforts. Through this examination, we hope to raise awareness and guide potential approaches to addressing this global health concern. PMID:25278579

Beyond recommendations: implementing food-based dietary guidelines for healthier populations.

PubMed

Smitasiri, Suttilak; Uauy, Ricardo

2007-03-01

To reduce the increased burden of diet-related disease and promote human potential through food and nutrition globally, harmonization of efforts is urgently needed. This article examines the concept of food-based dietary guidelines (FBDGs) and discusses the possibilities and challenges of harmonizing the process of developing and implementing dietary guidelines. The authors argue that while the development of FBDGs has contributed to the understanding of the role of nutrients and foods in achieving optimal health, the impact of these guidelines on human health has been limited. Science or evidence must be used in FBDG development; nevertheless, there are limitations in current nutrition science. FBDGs should address the health consequences of dietary insufficiency, excess, or imbalance with a broader perspective, considering the totality of the effects of a given dietary pattern, rather than focusing on single nutrients alone. Moreover, the food selection guideline should be seen as complementary to a strategic, comprehensive, and culturally appropriate dietary and health promoting intervention, and not only as a tool for providing nutrition policy and information. Technically, a single unified global set of FBDGs may be desirable and even achievable. This concept, however, presents novel challenges on how to address cultural diversity and the complex social, economic, and political interactions between humans and the food supply, not to mention the complexity of its communication and implementation. Therefore, global harmonized efforts in support of strategic dietary interventions, together with strong global scientific support and facilitation for the development and communication of FBDGs at national or regional levels, are proposed to implement FBDGs for healthier populations.

Reductions in global biodiversity loss predicted from conservation spending.

PubMed

Waldron, Anthony; Miller, Daniel C; Redding, Dave; Mooers, Arne; Kuhn, Tyler S; Nibbelink, Nate; Roberts, J Timmons; Tobias, Joseph A; Gittleman, John L

2017-11-16

Halting global biodiversity loss is central to the Convention on Biological Diversity and United Nations Sustainable Development Goals, but success to date has been very limited. A critical determinant of success in achieving these goals is the financing that is committed to maintaining biodiversity; however, financing decisions are hindered by considerable uncertainty over the likely impact of any conservation investment. For greater effectiveness, we need an evidence-based model that shows how conservation spending quantitatively reduces the rate of biodiversity loss. Here we demonstrate such a model, and empirically quantify how conservation investment reduced biodiversity loss in 109 countries (signatories to the Convention on Biological Diversity and Sustainable Development Goals), by a median average of 29% per country between 1996 and 2008. We also show that biodiversity changes in signatory countries can be predicted with high accuracy, using a dual model that balances the effects of conservation investment against those of economic, agricultural and population growth (human development pressures). Decision-makers can use this model to forecast the improvement that any proposed biodiversity budget would achieve under various scenarios of human development pressure, and then compare these forecasts to any chosen policy target. We find that the impact of spending decreases as human development pressures grow, which implies that funding may need to increase over time. The model offers a flexible tool for balancing the Sustainable Development Goals of human development and maintaining biodiversity, by predicting the dynamic changes in conservation finance that will be needed as human development proceeds.

Reductions in global biodiversity loss predicted from conservation spending

NASA Astrophysics Data System (ADS)

Waldron, Anthony; Miller, Daniel C.; Redding, Dave; Mooers, Arne; Kuhn, Tyler S.; Nibbelink, Nate; Roberts, J. Timmons; Tobias, Joseph A.; Gittleman, John L.

2017-11-01

Halting global biodiversity loss is central to the Convention on Biological Diversity and United Nations Sustainable Development Goals, but success to date has been very limited. A critical determinant of success in achieving these goals is the financing that is committed to maintaining biodiversity; however, financing decisions are hindered by considerable uncertainty over the likely impact of any conservation investment. For greater effectiveness, we need an evidence-based model that shows how conservation spending quantitatively reduces the rate of biodiversity loss. Here we demonstrate such a model, and empirically quantify how conservation investment between 1996 and 2008 reduced biodiversity loss in 109 countries (signatories to the Convention on Biological Diversity and Sustainable Development Goals), by a median average of 29% per country. We also show that biodiversity changes in signatory countries can be predicted with high accuracy, using a dual model that balances the effects of conservation investment against those of economic, agricultural and population growth (human development pressures). Decision-makers can use this model to forecast the improvement that any proposed biodiversity budget would achieve under various scenarios of human development pressure, and then compare these forecasts to any chosen policy target. We find that the impact of spending decreases as human development pressures grow, which implies that funding may need to increase over time. The model offers a flexible tool for balancing the Sustainable Development Goals of human development and maintaining biodiversity, by predicting the dynamic changes in conservation finance that will be needed as human development proceeds.

Recent Advancements in the Global Understanding of what Drives Heatwaves

NASA Astrophysics Data System (ADS)

Perkins-Kirkpatrick, S.

2016-12-01

Heatwaves, defined as prolonged periods of extreme heat, are disastrous events that impact human, natural and industrial systems all over the world. In recent years, the global research effort has greatly increased our understanding on quantifying heatwaves and how they have changed, what drives them, and their future projections. This talk will summarize critical developments made in this field, with particular emphasis on the physical driving mechanisms and the role of internal climate variability. Case studies from various global regions will illustrate both similarities and differences in the physical set-ups of these fascinating events. Future projections of heatwaves and the human contribution behind specific observed heatwave events will be briefly discussed. The talk will conclude by highlighting research priorities such that future investigation is targeted, and closes existing knowledge gaps on what drives heatwaves as effectively as possible. Such developments will ultimately aid in the predictability of heatwaves, thus aiding in reducing their devastating impacts.

Bioseguridad in Mexico: Pursuing Security between Local and Global Biologies.

PubMed

Wanderer, Emily Mannix

2017-09-01

In the aftermath of the 2009 outbreak of H1N1 influenza, scientists in Mexico sought to develop bioseguridad, that is, to protect biological life in Mexico by safely conducting research on infectious disease. Drawing on ethnographic research in laboratories and with scientists in Mexico, I look at how scientists make claims about local differences in regulations, infrastructure, bodies, and culture. The scientists working with infectious microbes sought to establish how different microbial ecologies, human immune systems, and political and regulatory systems made the risks of research different in Mexico from other countries. In developing bioseguridad, the idea of globalized biology that animates many public health projects was undermined as scientists attended to the elements of place that affected human health and safety. Scientists argued for the importance of local biologies, generating tension with global public health projects and regulations premised on the universality of biology. © 2016 by the American Anthropological Association.

A Visual Dashboard for Moving Health Technologies From “Lab to Village”

PubMed Central

Singer, Peter A

2007-01-01

New technologies are an important way of addressing global health challenges and human development. However, the road for new technologies from “lab to village” is neither simple nor straightforward. Until recently, there has been no conceptual framework for analyzing and addressing the myriad forces and issues involved in moving health technologies from the lab to those who need them. Recently, based on empirical research, we published such a model. In this paper, we focus on extending the model into a dashboard and examine how this dashboard can be used to manage the information related to the path from lab to village. The next step will be for groups interested in global health, and even the public via the Internet, to use the tool to help guide technologies down this tricky path to improve global health and foster human development. PMID:17951216

Adapting global influenza management strategies to address emerging viruses.

PubMed

Noah, Diana L; Noah, James W

2013-07-15

Death by respiratory complications from influenza infections continues to be a major global health concern. Antiviral drugs are widely available for therapy and prophylaxis, but viral mutations have resulted in resistance that threatens to reduce the long-term utility of approved antivirals. Vaccination is the best method for controlling influenza, but vaccine strategies are blunted by virus antigenic drift and shift. Genetic shift in particular has led to four pandemics in the last century, which have prompted the development of efficient global surveillance and vaccination programs. Although the influenza pandemic of 2009 emphasized the need for the rapid standardization of global surveillance methods and the preparation and dissemination of global assay standards for improved reporting and diagnostic tools, outbreaks of novel influenza strains continue to occur, and current efforts must be enhanced by aggressive public education programs to promote increased vaccination rates in the global population. Recently, a novel H7N9 avian influenza virus with potential to become a pandemic strain emerged in China and was transmitted from animals to humans with a demonstrated >20% mortality rate. Sporadic outbreaks of highly lethal avian virus strains have already increased public awareness and altered annual vaccine production strategies to prevent the natural adaption of this virus to human-to-human transmission. Additional strategies for combating influenza include advancement of new antivirals for unexploited viral or host cellular targets; novel adjuvants and alternate vaccine delivery systems; and development of universal protein, DNA, or multivalent vaccines designed to increase immune responsiveness and enhance public health response times.

Developing Learning Environments: Challenges for Theory, Research and Practice.

ERIC Educational Resources Information Center

Iles, Paul

1994-01-01

Key challenges in development of learning organizations, promotion of learning culture, enhancement of learning processes, and development of learning communities are appropriateness of current models for interdisciplinary teams; whether valuing diversity enhances effectiveness; how global human resource development affects domestic; and what…

Sustainability. Systems integration for global sustainability.

PubMed

Liu, Jianguo; Mooney, Harold; Hull, Vanessa; Davis, Steven J; Gaskell, Joanne; Hertel, Thomas; Lubchenco, Jane; Seto, Karen C; Gleick, Peter; Kremen, Claire; Li, Shuxin

2015-02-27

Global sustainability challenges, from maintaining biodiversity to providing clean air and water, are closely interconnected yet often separately studied and managed. Systems integration—holistic approaches to integrating various components of coupled human and natural systems—is critical to understand socioeconomic and environmental interconnections and to create sustainability solutions. Recent advances include the development and quantification of integrated frameworks that incorporate ecosystem services, environmental footprints, planetary boundaries, human-nature nexuses, and telecoupling. Although systems integration has led to fundamental discoveries and practical applications, further efforts are needed to incorporate more human and natural components simultaneously, quantify spillover systems and feedbacks, integrate multiple spatial and temporal scales, develop new tools, and translate findings into policy and practice. Such efforts can help address important knowledge gaps, link seemingly unconnected challenges, and inform policy and management decisions. Copyright © 2015, American Association for the Advancement of Science.

Cryptococcus: from environmental saprophyte to global pathogen

PubMed Central

May, Robin C.; Stone, Neil R.H.; Wiesner, Darin L.; Bicanic, Tihana; Nielsen, Kirsten

2016-01-01

Cryptococcosis is a globally distributed invasive fungal infection that is caused by species within the genus Cryptococcus which presents substantial therapeutic challenges. Although natural human-to-human transmission has never been observed, recent work has identified multiple virulence mechanisms that enable cryptococci to infect, disseminate within and ultimately kill their human host. In this Review, we describe these recent discoveries that illustrate the intricacy of host-pathogen interactions and reveal new details about the host immune responses that either help to protect against disease or increase host susceptibility. In addition, we discuss how this improved understanding of both the host and the pathogen informs potential new avenues for therapeutic development. PMID:26685750

Cryptococcus: from environmental saprophyte to global pathogen.

PubMed

May, Robin C; Stone, Neil R H; Wiesner, Darin L; Bicanic, Tihana; Nielsen, Kirsten

2016-02-01

Cryptococcosis is a globally distributed invasive fungal infection that is caused by species within the genus Cryptococcus which presents substantial therapeutic challenges. Although natural human-to-human transmission has never been observed, recent work has identified multiple virulence mechanisms that enable cryptococci to infect, disseminate within and ultimately kill their human host. In this Review, we describe these recent discoveries that illustrate the intricacy of host-pathogen interactions and reveal new details about the host immune responses that either help to protect against disease or increase host susceptibility. In addition, we discuss how this improved understanding of both the host and the pathogen informs potential new avenues for therapeutic development.

The influence of globalization on medical regulation: a descriptive analysis of international medical graduates registered through alternative licensure routes in Ontario

PubMed Central

Yen, Wendy; Hodwitz, Kathryn; Thakkar, Niels; Martimianakis, Maria Athina (Tina); Faulkner, Dan

2016-01-01

The increasing globalization of the medical profession has influenced health policy, health human resource planning, and medical regulation in Canada. Since the early 2000s, numerous policy initiatives have been created to facilitate the entry of international medical graduates (IMGs) into the Canadian workforce. In Ontario, the College of Physicians and Surgeons of Ontario (CPSO) developed alternative licensure routes to increase the ability of qualified IMGs to obtain licenses to practice. The current study provides demographic and descriptive information about the IMGs registered through the CPSO’s alternative licensure routes between 2000 and 2012. An analysis of the characteristics and career trajectories of all IMGs practicing in the province sheds light on broader globalization trends and raises questions about the future of health human resource planning in Canada. As the medical profession becomes increasingly globalized, health policy and regulation will continue to be influenced by trends in international migration, concerns about global health equity, and the shifting demographics of the Canadian physician workforce. Implications for future policy development in the complex landscape of medical education and practice are discussed. PMID:28344705

Gender norms as health harms: reclaiming a life course perspective on sexual and reproductive health and rights.

PubMed

Crockett, Cailin; Cooper, Bergen

2016-11-01

Despite their demographic significance and the lifetime impact of gender disparities on their health and rights, women considered older than reproductive age are excluded from most investments in global public health. While development policies linking human rights with access to sexual and reproductive healthcare have yielded progress towards improving the status of women and girls, older women have not benefited from these initiatives. Yet as women grow older, they experience a range of health conditions rooted in their reproductive biology - from ageing with fistula, to cervical and breast cancers. Current approaches to global women's health ignore these serious conditions, harming older women through the perpetuation of gender norms that construe women's health through a narrow reproductive lens. Meanwhile, older women are generally absent from global ageing discourse, which lacks a gender perspective, creating a dual invisibility as the field of global women's health presumes ageing women are accounted for. Reclaiming the sexual rights framework suggested by the International Conference on Population and Development and the Beijing Platform for Action, we call for the revision of global health policies to incorporate a life course approach to women's health as a matter of human rights. Published by Elsevier B.V.

Higher Resolution for Water Resources Studies

NASA Astrophysics Data System (ADS)

Dumenil-Gates, L.

2009-12-01

The Earth system science community is providing an increasing range of science results for the benefit of achieving the Millennium Development Goals. In addressing questions such as reducing poverty and hunger, achieving sustainable global development, or by defining adaptation strategies for climate change, one of the key issues will be the quantitative description and understanding of the global water cycle, which will allow useful projections of available future water resources for several decades ahead. The quantities of global water cycle elements that we observe today - and deal with in hydrologic and atmospheric modeling - are already very different from the natural flows as human influence on the water cycle by storage, consumption and edifice has been going on for millennia, and climate change is expected to add more uncertainty. In this case Tony Blair’s comment that perhaps the most worrying problem is climate change does not cover the full story. We shall also have to quantify how the human demand for water resources and alterations of the various elements of the water cycle may proceed in the future: will there be enough of the precious water resource to sustain current and future demands by the various sectors involved? The topics that stakeholders and decision makers concerned with managing water resources are interested in cover a variety of human uses such as agriculture, energy production, ecological flow requirements to sustain biodiversity and ecosystem services, or human cultural aspects, recreation and human well-being - all typically most relevant at the regional or local scales, this being quite different from the relatively large-scale that the IPCC assessment addresses. Halfway through the Millennium process, the knowledge base of the global water cycle is still limited. The sustainability of regional water resources is best assessed through a research program that combines high-resolution climate and hydrologic models for expected future scenarios (as in the IPCC ensembles) with appropriate observational data under current conditions in order to benchmark the models’ accuracy. Expected future changes in water availability could then be characterized and appropriate adaptation action designed in co-operation with the water use community. In situ observations of water cycle variables can also be used and developed together with remote sensing data from space to provide initial data for global seasonal or decadal forecasting and monitoring of global change in less well observed regions of the world.

Lines of evidence for environmentally driven human migration

NASA Astrophysics Data System (ADS)

Davis, K. F.; D'Odorico, P.

2012-12-01

International human migration is an important mechanism that affects, and is affected by, various human and natural systems. With the number of people living outside their countries of origin currently estimated at 214 million people and projected to potentially reach more than 400 million people by mid-century, the topic of international human movements presents possible advantages and pitfalls for both sending and receiving countries on multiple fronts (e.g. economic, environmental, political and cultural). Understanding how human migration interacts with human and natural systems is therefore essential in realizing a sustainable and balanced future. While the study of international migration has historically been motivated largely by economic and political interests, the issue of environmentally induced migration has become increasingly important in light of a rapidly changing climate in conjunction with increasing population pressure on many important resources. Particularly in terms of theoretical and conceptual discussions, environmentally induced human migration has been receiving increased attention in the literature. To date, few studies - many of which focus on internal (intra-national) or regional migration - have attempted to quantify the interactions of human migration and the environment, with little attention paid to the global scale as a result of varying regional factors and lack of sufficient data. Recently available global bilateral migration datasets have been developed that allow for a more comprehensive understanding of human movements between all countries. With these datasets, we seek to elucidate environmental drivers of human migration over the past half-century using a multi-pronged approach. First, using a recently developed universal radiation model, we examine human movements based solely on global population distribution. Next, by comparison of migration movements with selected economic, environmental and human welfare indicators, we determine additional factors that may help explain migration at global, regional, continental and community-based (i.e. maximized module) scales. Lastly, we explore the relationship between migration and natural disasters (e.g. drought, flooding) to identify instances in which the environment is a proximate cause of human displacement and in turn use this information to determine if a subsequent cascade of human movements appears in neighboring countries as a result of the elevated inflow of migrants from the initial country of interest. In this way, we seek to gain a fuller picture of the environmental factors driving the dynamics of modern human migration.

Global Environmental Change: Modifying Human Contributions Through Education

NASA Astrophysics Data System (ADS)

Carter, Lynne M.

1998-12-01

The 1995 Intergovernmental Panel on Climate Change (IPCC, 1996) Science report concludes that evidence now available "points toward a discernible human influence on global climate" (p. 439). Reductions in emissions will require changes in human behavior. This study assessed whether gains in global environmental change knowledge would lead to changes in human behaviors that could be deemed environmentally responsible. The study assessed the impact on participant behavior of a two-and-one-half day National Informal Educators Workshop and Videoconference held November 14-16, 1994. The workshops were located in seven down-link sites around the continental U.S. and Hawaii. The program utilized a variety of pedagogical techniques during five hours of satellite programming with national expertise on global change topics (natural variability, greenhouse effect, ozone depletion, ecosystem response, and population and resource distribution) and applications of that information with local experts in regional workshops. Participants implemented many personal and professional behavior changes after participation in this program. Six behavior change scales were created from assessment of survey responses (four coefficient alphas were above .7, one was .68, and one was .58). Personal behavior changes grouped into three categories: Use of Fewer Resources (acts of everyday life generally under volitional control), Purchasing Choices/Options (less frequent acts, not under total volitional control, with significant environmental effect over the lifetime of the decision, e.g., an automobile) and Increased Awareness and Discussion (indicating changes in "habits of mind"). The professional behavior changes also grouped into three categories: Curriculum Development (developing/revising curricula including new knowledge); Networking (with colleagues from the program); and Office Procedures (reflecting environmentally responsible behavior). The statistically significant behavior changes implemented correspond with increases in content knowledge, confidence, a developing national network, regional applications, and satisfaction with the program.

Increasing human dominance of tropical forests.

PubMed

Lewis, Simon L; Edwards, David P; Galbraith, David

2015-08-21

Tropical forests house over half of Earth's biodiversity and are an important influence on the climate system. These forests are experiencing escalating human influence, altering their health and the provision of important ecosystem functions and services. Impacts started with hunting and millennia-old megafaunal extinctions (phase I), continuing via low-intensity shifting cultivation (phase II), to today's global integration, dominated by intensive permanent agriculture, industrial logging, and attendant fires and fragmentation (phase III). Such ongoing pressures, together with an intensification of global environmental change, may severely degrade forests in the future (phase IV, global simplification) unless new "development without destruction" pathways are established alongside climate change-resilient landscape designs. Copyright © 2015, American Association for the Advancement of Science.

Earth science information: Planning for the integration and use of global change information

NASA Technical Reports Server (NTRS)

Lousma, Jack R.

1992-01-01

Activities and accomplishments of the first six months of the Consortium for International Earth Science Information Network (CIESIN's) 1992 technical program have focused on four main missions: (1) the development and implementation of plans for initiation of the Socioeconomic Data and Applications Center (SEDAC) as part of the EOSDIS Program; (2) the pursuit and development of a broad-based global change information cooperative by providing systems analysis and integration between natural science and social science data bases held by numerous federal agencies and other sources; (3) the fostering of scientific research into the human dimensions of global change and providing integration between natural science and social science data and information; and (4) the serving of CIESIN as a gateway for global change data and information distribution through development of the Global Change Research Information Office and other comprehensive knowledge sharing systems.

Atypical Local Interference Affects Global Processing in Children with Neurofibromatosis Type 1.

PubMed

Payne, Jonathan M; Porter, Melanie A; Bzishvili, Samantha; North, Kathryn N

2017-05-01

To examine hierarchical visuospatial processing in children with neurofibromatosis type 1 (NF1), a single gene disorder associated with visuospatial impairments, attention deficits, and executive dysfunction. We used a modified Navon paradigm consisting of a large "global" shape composed of smaller "local" shapes that were either congruent (same) or incongruent (different) to the global shape. Participants were instructed to name either the global or local shape within a block. Reaction times, interference ratios, and error rates of children with NF1 (n=30) and typically developing controls (n=24) were compared. Typically developing participants demonstrated the expected global processing bias evidenced by a vulnerability to global interference when naming local stimuli without a cost of congruence when naming global stimuli. NF1 participants, however, experienced significant interference from the unattended level when naming both local and global levels of the stimuli. Findings suggest that children with NF1 do not demonstrate the typical human bias of processing visual information from a global perspective. (JINS, 2017, 23, 446-450).

Categorizing Biomarkers of the Human Exposome and Developing Metrics for Assessing Environmental Sustainability

EPA Science Inventory

The concept of maintaining environmental sustainability broadly encompasses all human activities that impact the global environment, including the production of energy, use and management of finite resources such as petrochemicals, metals, food production (farmland, fresh and oce...

The global forum on environment and development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-01-01

The first Global Conference of Spiritual and Parliamentary Leaders on Human Survival was held in Oxford, England not to discuss world issues, but to test the ability of 100 spiritual leaders and 100 parliamentarians to work together in a world which has preferred to separate church and state. This conference, held in Moscow, attracted more than 1,000 people. The main purpose was to find common solutions to environmental quality, economic development, and human survival as citizens of planet Earth. Notable addresses were heard from Javier Perez de Cuellar, Senator Albert Gore, Carl Sagan, Lester Brown, Nafis Sadik, Evguenij Velikhov, andmore » Mikhail Gorbachev who advocated an International Green Cross.« less

Development of Newborn and Infant Vaccines

PubMed Central

Sanchez-Schmitz, Guzman; Levy, Ofer

2014-01-01

Vaccines for early-life immunization are a crucial biomedical intervention to reduce global morbidity and mortality, yet their developmental path has been largely ad hoc, empiric, and inconsistent. Immune responses of human newborns and infants are distinct and cannot be predicted from those of human adults or animal models. Therefore, understanding and modeling age-specific human immune responses will be vital to the rational design and development of safe and effective vaccines for newborns and infants. PMID:21734174

Global modeling of withdrawal, allocation and consumptive use of surface water and groundwater resources

NASA Astrophysics Data System (ADS)

Wada, Y.; Wisser, D.; Bierkens, M. F. P.

2014-01-01

To sustain growing food demand and increasing standard of living, global water withdrawal and consumptive water use have been increasing rapidly. To analyze the human perturbation on water resources consistently over large scales, a number of macro-scale hydrological models (MHMs) have been developed in recent decades. However, few models consider the interaction between terrestrial water fluxes, and human activities and associated water use, and even fewer models distinguish water use from surface water and groundwater resources. Here, we couple a global water demand model with a global hydrological model and dynamically simulate daily water withdrawal and consumptive water use over the period 1979-2010, using two re-analysis products: ERA-Interim and MERRA. We explicitly take into account the mutual feedback between supply and demand, and implement a newly developed water allocation scheme to distinguish surface water and groundwater use. Moreover, we include a new irrigation scheme, which works dynamically with a daily surface and soil water balance, and incorporate the newly available extensive Global Reservoir and Dams data set (GRanD). Simulated surface water and groundwater withdrawals generally show good agreement with reported national and subnational statistics. The results show a consistent increase in both surface water and groundwater use worldwide, with a more rapid increase in groundwater use since the 1990s. Human impacts on terrestrial water storage (TWS) signals are evident, altering the seasonal and interannual variability. This alteration is particularly large over heavily regulated basins such as the Colorado and the Columbia, and over the major irrigated basins such as the Mississippi, the Indus, and the Ganges. Including human water use and associated reservoir operations generally improves the correlation of simulated TWS anomalies with those of the GRACE observations.

Global Modeling of Withdrawal, Allocation and Consumptive Use of Surface Water and Groundwater Resources

NASA Astrophysics Data System (ADS)

Wada, Y.; Wisser, D.; Bierkens, M. F.

2014-12-01

To sustain growing food demand and increasing standard of living, global water withdrawal and consumptive water use have been increasing rapidly. To analyze the human perturbation on water resources consistently over large scales, a number of macro-scale hydrological models (MHMs) have been developed in recent decades. However, few models consider the interaction between terrestrial water fluxes, and human activities and associated water use, and even fewer models distinguish water use from surface water and groundwater resources. Here, we couple a global water demand model with a global hydrological model and dynamically simulate daily water withdrawal and consumptive water use over the period 1979-2010, using two re-analysis products: ERA-Interim and MERRA. We explicitly take into account the mutual feedback between supply and demand, and implement a newly developed water allocation scheme to distinguish surface water and groundwater use. Moreover, we include a new irrigation scheme, which works dynamically with a daily surface and soil water balance, and incorporate the newly available extensive global reservoir data set (GRanD). Simulated surface water and groundwater withdrawals generally show good agreement with reported national and sub-national statistics. The results show a consistent increase in both surface water and groundwater use worldwide, with a more rapid increase in groundwater use since the 1990s. Human impacts on terrestrial water storage (TWS) signals are evident, altering the seasonal and inter-annual variability. This alteration is particularly large over heavily regulated basins such as the Colorado and the Columbia, and over the major irrigated basins such as the Mississippi, the Indus, and the Ganges. Including human water use and associated reservoir operations generally improves the correlation of simulated TWS anomalies with those of the GRACE observations.

Australia's contribution to global immunisation.

PubMed

Ruff, Tilman A; Taylor, Kate; Nolan, Terry

2012-12-01

To review Australian contributions to global immunisation. We summarise Australian scientific and program contributions to vaccines and global immunisation, describe key developments and strengths in Australia's national immunisation program, and outline how both of these can link with Australia's increasing international development budget to build Australia's future contribution to global immunisation. Australian contributions to vaccines and immunisation have been substantial, and Australia offers a range of good practices in its domestic and development approaches. There are major opportunities to build on this strong track record. These include committing to help roll out important new life-saving vaccines against pneumococcal disease, rotavirus and human papilloma virus (HPV) to the children who need them most, but whose communities can least afford them. Australia is one of a few countries expanding their aid budgets towards 0.7% development assistance and other development commitments. Given the importance of immunisation to health gains, Australia is well placed to expand its investment in immunisation within its development portfolio. The GAVI Alliance is the best-established global mechanism to do this. Additionally, however, Australia could harness other national and regional mechanisms to support low and middle-income countries, thereby complementing GAVI's focus and global needs. © 2012 The Authors. ANZJPH © 2012 Public Health Association of Australia.

Accelerating Next Generation Vaccine Development for Global Disease Prevention

PubMed Central

Koff, Wayne C; Burton, Dennis R.; R.Johnson, Philip; Walker, Bruce D.; King, Charles R.; Nabel, Gary J.; Ahmed, Rafi; Bhan, Maharaj Kishan; Plotkin, Stanley A.

2014-01-01

Summary Vaccines are among the greatest successes in the history of public health. However, past strategies for vaccine development are unlikely to succeed in the future against major global diseases such as AIDS, TB, and malaria. For such diseases, the correlates of protection are poorly defined and the pathogens evade immune detection and/or exhibit extensive genetic variability. Recent advances have heralded in a new era of vaccine discovery. However, translation of these advances into vaccines remains impeded by lack of understanding of key vaccinology principles in humans. We review these advances towards vaccine discovery and suggest that for accelerating successful vaccine development, new human immunology-based clinical research initiatives be implemented with the goal of elucidating and more effectively inducing vaccine-induced protective immune responses. PMID:23723240

Assessing Anthropogenic Impacts on Tunas, Sharks and Billfishes with Direct Observations of Human Fishers on the High Seas

NASA Astrophysics Data System (ADS)

Block, B.; Ferretti, F.; White, T.; De Leo, G.; Hazen, E. L.; Bograd, S. J.

2016-12-01

Anthropogenic impacts on marine predators have been examined within exclusive economic zones, but few data sets have enabled assessing human fishing impacts on the high seas. By combining large electronic tagging databases archiving mobile predator movements (e.g. Tagging of Pacific Pelagics, TAG A Giant, Animal Telemetry Network) with the global fishing catch and fishing effort data, from satellite tracks of vessels on the high seas (AIS), a better understanding of human use and exploitation at a global scale can be obtained. This capacity to combine the movements of mobile ocean predators (tunas, sharks, billfishes) with analyses of their human predator's behaviors, via examination of the global fishing fleet activities is unprecedented due to the new access researchers are garnering to these big satellite derived AIS databases. Global Fishing Watch is one example of such a data provider, that now makes accessible, the AIS data from the global community of maritime vessels, and has developed along with researchers new algorithms that delineate distinct types of fishing vessel behaviors (longline, purse seiner) and effort. When combined with satellite tagging data of mobile apex predators, oceanographic preferences, records of fishing fleets catches, targeted species and economic drivers of fisheries, new quantitative insights can be gained about the catch reporting of fleets, and the pelagic species targeted at a global scale. Research communities can now also examine how humans behave on the high seas, and potentially improve how fish stocks, such as tunas, billfishes, and sharks are exploited. The capacity to gather information on diverse human fishing fleets and behaviors remotely, should provide a wealth of new tools that can potentially be applied toward the resource management efforts surrounding these global fishing fleets. This type of information is essential for prioritizing regions of conservation concern for megaufauna swimming in our oceans.

GlobAl Distribution of GEnetic Traits (GADGET) web server: polygenic trait scores worldwide.

PubMed

Chande, Aroon T; Wang, Lu; Rishishwar, Lavanya; Conley, Andrew B; Norris, Emily T; Valderrama-Aguirre, Augusto; Jordan, I King

2018-05-18

Human populations from around the world show striking phenotypic variation across a wide variety of traits. Genome-wide association studies (GWAS) are used to uncover genetic variants that influence the expression of heritable human traits; accordingly, population-specific distributions of GWAS-implicated variants may shed light on the genetic basis of human phenotypic diversity. With this in mind, we developed the GlobAl Distribution of GEnetic Traits web server (GADGET http://gadget.biosci.gatech.edu). The GADGET web server provides users with a dynamic visual platform for exploring the relationship between worldwide genetic diversity and the genetic architecture underlying numerous human phenotypes. GADGET integrates trait-implicated single nucleotide polymorphisms (SNPs) from GWAS, with population genetic data from the 1000 Genomes Project, to calculate genome-wide polygenic trait scores (PTS) for 818 phenotypes in 2504 individual genomes. Population-specific distributions of PTS are shown for 26 human populations across 5 continental population groups, with traits ordered based on the extent of variation observed among populations. Users of GADGET can also upload custom trait SNP sets to visualize global PTS distributions for their own traits of interest.

Measuring the Impact of the Human Rights on Health in Global Health Financing.

PubMed

Davis, Sara L M

2015-12-10

In response to new scientific developments, UNAIDS, WHO, and global health financing institutions have joined together to promote a "fast-track" global scale-up of testing and treatment programs. They have set ambitious targets toward the goal of ending the three diseases by 2030. These numerical indicators, based on infectious disease modeling, can assist in measuring countries' progressive realization of the right to health. However, they only nominally reference the catastrophic impact that human rights abuses have on access to health services; they also do not measure the positive impact provided by law reform, legal aid, and other health-related human rights programs. Drawing on experience at the Global Fund to Fight AIDS, Tuberculosis and Malaria, which has incorporated expanded stakeholder consultation and human rights programming into its grants, the article argues that addressing human rights barriers to access is often an ad hoc activity occurring on the sidelines of a health grantmaking process that has focused on the scale-up of biomedical programs to meet global health indicators. To ensure that these biomedical programs have impact, UN agencies and health financing mechanisms must begin to more systematically and proactively integrate human rights policy and practice into their modeling and measurement tools. Copyright © 2015 Davis. This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

Family planning: a basic development need.

PubMed

1994-06-01

The 1994 Human Development Report from the United Nations Development Program (UNDP) proposes a 20-20 Human Development Compact based on shared responsibilities between poor and rich nations, whereby poor and rich nations would help unmet basic human development needs such as primary education, primary health care, safe drinking water, and family planning over the next 10 years. This would require an additional US $30 to US $40 billion annually. Developing countries would commit 20% of their budgets to human priority concerns instead of the current 10% by reducing military expenditure, selling off unprofitable public enterprises and abandoning wasteful prestige projects. Donor countries would increase foreign aid from the current average of 7% to 20%. The report will propose a new concept of human security at the World Summit for Social Development to be held in March 1995, calling widespread human insecurity a universal problem. On average, poor nations have 19 soldiers for every one doctor. Global military spending has been declining since 1987 at the rate of 3.6% a year, resulting in a cumulative peace dividend of US $935 billion from 1987 to 1994. But this money has not been expended on unmet human needs. India ordered fighter planes at a cost that could have provided basic education to the 15 million Indian girls now out of school. Nigeria bought tanks from the UK at a cost that could have immunized all 2 million unimmunized children while also providing family planning to nearly 17 million couples. UNDP proposes a phasing out of all military assistance, military bases, and subsidies to arms exporters over a 3-year period. It also recommends the major restructuring of existing aid funds, and proposes a serious study on new institutions for global governance in the next century.

The Future Role of the United States in Global Health: Emphasis on Cardiovascular Disease.

PubMed

Fuster, Valentin; Frazer, Jendayi; Snair, Megan; Vedanthan, Rajesh; Dzau, Victor

2017-12-26

U.S. global health investment has focused on detection, treatment, and eradication of infectious diseases such as tuberculosis, malaria, and human immunodeficiency virus/acquired immunodeficiency syndrome, with significant results. Although efforts should be maintained and expanded to provide ongoing therapy for chronic infectious disease, there is a pressing need to meet the challenge of noncommunicable diseases, which constitute the highest burden of diseases globally. A Committee of the National Academies of Sciences, Engineering, and Medicine has made 14 recommendations that require ongoing commitments to eradication of infectious disease and increase the emphasis on chronic diseases such as cardiovascular disease. These include improving early detection and treatment, mitigating disease risk factors, shifting global health infrastructure to include management of cardiovascular disease, developing global partners and private-public ventures to meet infrastructure and funding challenges, streamlining medical product development and supply, increasing research and development capacity, and addressing gaps in global political and institutional leadership to meet the shifting challenge. Copyright © 2017. Published by Elsevier Inc.

Global justice, capabilities approach and commercial surrogacy in India.

PubMed

Saravanan, Sheela

2015-08-01

Inequalities, ineffective governance, unclear surrogacy regulations and unethical practices make India an ideal environment for global injustice in the process of commercial surrogacy. This article aims to apply the 'capabilities approach' to find possibilities of global justice through human fellowship in the context of commercial surrogacy. I draw primarily on my research findings supplemented by other relevant empirical research and documentary films on surrogacy. The paper reveals inequalities and inadequate basic entitlements among surrogate mothers as a consequence of which they are engaged in unjust contracts. Their limited entitlements also limit their opportunities to engage in enriching goals. It is the role of the state to provide all its citizens with basic entitlements and protect their basic human rights. Individuals in India evading their basic duty also contribute to the existing inequalities. Individual responsibilities of the medical practitioners and the intended parents are in question here as they are more inclined towards self-interest rather than commitment towards human fellowship. At the global level, the injustice in transnational commercial surrogacy practices in developing countries calls for an international declaration of women and child rights in third party reproduction with a normative vision of mutual fellowship and human dignity.

The Influence of Low-carbon Economy on Global Trade Pattern

NASA Astrophysics Data System (ADS)

Xiao-jing, Guo

Since global warming has seriously endangered the living environment of human being and their health and safety, the development of low-carbon economy has become an irreversible global trend. Under the background of economic globalization, low-carbon economy will surely exert a significant impact on global trade pattern. Countries are paying more and more attention to the green trade. The emission permits trade of carbon between the developed countries and the developing countries has become more mature than ever. The carbon tariff caused by the distribution of the "big cake" will make the low-cost advantage in developing countries cease to exist, which will, in turn, affect the foreign trade, economic development, employment and people's living in developing countries. Therefore, under the background of this trend, we should perfect the relevant laws and regulations on trade and environment as soon as possible, optimize trade structure, promote greatly the development of service trade, transform thoroughly the mode of development in foreign trade, take advantage of the international carbon trading market by increasing the added value of export products resulted from technological innovation to achieve mutual benefit and win-win results and promote common development.

Thinking Out of the Box: A Green and Social Climate Fund Comment on "Politics, Power, Poverty and Global Health: Systems and Frames".

PubMed

Ooms, Gorik; Pas, Remco van de; Decoster, Kristof; Hammonds, Rachel

2016-12-28

Solomon Benatar's paper "Politics, Power, Poverty and Global Health: Systems and Frames" examines the inequitable state of global health challenging readers to extend the discourse on global health beyond conventional boundaries by addressing the interconnectedness of planetary life. Our response explores existing models of international cooperation, assessing how modifying them may achieve the twin goals of ensuring healthy people and planet. First, we address why the inequality reducing post World War II European welfare model, if implemented state-by-state, is unfit for reducing global inequality and respecting environmental boundaries. Second, we argue that to advance beyond the 'Westphalian,' human centric thinking integral to global inequality and climate change requires challenging the logic of global economic integration and exploring the politically infeasible. In conclusion, we propose social policy focused changes to the World Trade Organisation (WTO) and a Green and Social Climate Fund, financed by new global greenhouse gas charges, both of which could advance human and planetary health. Recent global political developments may offer a small window of opportunity for out of the box proposals that could be advanced by concerted and united advocacy by global health activists, environmental activists, human rights activists, and trade unions. © 2017 The Author(s); Published by Kerman University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

The Geography of Greenhouse Gas Emissions: Hands-On! Developing Active Learning Modules on the Human Dimensions of Global Change.

ERIC Educational Resources Information Center

Liverman, Diana; Solem, Michael

This learning module aims to engage students in problem solving, critical thinking, scientific inquiry, and cooperative learning. The module is appropriate for use in any introductory or intermediate undergraduate course that focuses on human-environment relationships. The module examines the geography of human activities that produce the major…

Securing the Human: The Journey Toward World Law and Justice. The Whole Earth Papers, No. 14.

ERIC Educational Resources Information Center

Mische, Patricia; And Others

The document contains a variety of papers that examine the linkages between local concerns and global concerns and explore alternative world futures. An introductory article, "Securing the Human," discusses how the world community needs to develop adequate means to deal with crimes against humans. These means include sound analysis, spiritual…

A Study on Teaching Quality of Taiwan Government Training Civil Servants with Educational Technology

ERIC Educational Resources Information Center

Hsiao, Luke H. C.

2012-01-01

When economic globalization, informatization, and marketization are rapidly developing, the world is reaching the globally industrial society based on information technology. In such a fierce competition, human resource is gradually placed on the critical role. This study aims to: (1) understand the present situation of Educational Technology and…

Considerations for Creating Multi-Language Personality Norms: A Three-Component Model of Error

ERIC Educational Resources Information Center

Meyer, Kevin D.; Foster, Jeff L.

2008-01-01

With the increasing globalization of human resources practices, a commensurate increase in demand has occurred for multi-language ("global") personality norms for use in selection and development efforts. The combination of data from multiple translations of a personality assessment into a single norm engenders error from multiple sources. This…

A Reciprocal Global Education? Working towards a More Humanizing Pedagogy through Critical Literacy

ERIC Educational Resources Information Center

Renner, Adam; Brown, Milton; Stiens, Gina; Burton, Sonya

2010-01-01

Dehumanizing tendencies within the present neo-liberal era provide the backdrop against which the authors have developed an 11-year partnership in the Global South. The economic context encourages competition over community and, while portending to bring people closer together through technological advances, it only facilitates the flow of…

Global Hubs and Global Nodes: Challenging Traditional Views of Communities, Clusters and Competitiveness

ERIC Educational Resources Information Center

Seline, Richard

2006-01-01

Five trends are emerging that will not only change the role of human capital in the United States but will also challenge the legacy system of workforce development, skills and competency-focused institutions, and assuredly, community colleges. Workforce investment boards, for example, are currently geographically constrained in environments that…

Global Trends in Workplace Learning

ERIC Educational Resources Information Center

Lee, Lung-Sheng; Lai, Chun-Chin

2012-01-01

The paradigm of human resource development has shifted to workplace learning and performance. Workplace can be an organization, an office, a kitchen, a shop, a farm, a website, even a home. Workplace learning is a dynamic process to solve workplace problems through learning. An identification of global trends of workplace learning can help us to…

The One Health Concept: 10 Years Old and a Long Road Ahead.

PubMed

Destoumieux-Garzón, Delphine; Mavingui, Patrick; Boetsch, Gilles; Boissier, Jérôme; Darriet, Frédéric; Duboz, Priscilla; Fritsch, Clémentine; Giraudoux, Patrick; Le Roux, Frédérique; Morand, Serge; Paillard, Christine; Pontier, Dominique; Sueur, Cédric; Voituron, Yann

2018-01-01

Over the past decade, a significant increase in the circulation of infectious agents was observed. With the spread and emergence of epizootics, zoonoses, and epidemics, the risks of pandemics became more and more critical. Human and animal health has also been threatened by antimicrobial resistance, environmental pollution, and the development of multifactorial and chronic diseases. This highlighted the increasing globalization of health risks and the importance of the human-animal-ecosystem interface in the evolution and emergence of pathogens. A better knowledge of causes and consequences of certain human activities, lifestyles, and behaviors in ecosystems is crucial for a rigorous interpretation of disease dynamics and to drive public policies. As a global good, health security must be understood on a global scale and from a global and crosscutting perspective, integrating human health, animal health, plant health, ecosystems health, and biodiversity. In this study, we discuss how crucial it is to consider ecological, evolutionary, and environmental sciences in understanding the emergence and re-emergence of infectious diseases and in facing the challenges of antimicrobial resistance. We also discuss the application of the "One Health" concept to non-communicable chronic diseases linked to exposure to multiple stresses, including toxic stress, and new lifestyles. Finally, we draw up a list of barriers that need removing and the ambitions that we must nurture for the effective application of the "One Health" concept. We conclude that the success of this One Health concept now requires breaking down the interdisciplinary barriers that still separate human and veterinary medicine from ecological, evolutionary, and environmental sciences. The development of integrative approaches should be promoted by linking the study of factors underlying stress responses to their consequences on ecosystem functioning and evolution. This knowledge is required for the development of novel control strategies inspired by environmental mechanisms leading to desired equilibrium and dynamics in healthy ecosystems and must provide in the near future a framework for more integrated operational initiatives.

Global Incidence and Mortality Rates of Stomach Cancer and the Human Development Index: an Ecological Study.

PubMed

Khazaei, Salman; Rezaeian, Shahab; Soheylizad, Mokhtar; Khazaei, Somayeh; Biderafsh, Azam

2016-01-01

Stomach cancer (SC) is the second leading cause of cancer death with the rate of 10.4% in the world. The correlation between the incidence and mortality rates of SC and human development index (HDI) has not been globally determined. Therefore, this study aimed to determine the association between the incidence and mortality rates of SC and HDI in various regions. In this global ecological study, we used the data about the incidence and mortality rate of SC and HDI from the global cancer project and the United Nations Development Programme database, respectively. In 2012, SCs were estimated to have affected a total of 951,594 individuals (crude rate: 13.5 per 100,000 individuals) with a male/female ratio of 1.97, and caused 723,073 deaths worldwide (crude rate: 10.2 per 100,000 individuals). There was a positive correlation between the HDI and both incidence (r=0.28, <0.05) and mortality rates of SC (r=0.13, P = 0.1) in the world in 2012. The high incidence and mortality rates of SC in countries with high and very high HDI is remarkable which should be the top priority of interventions for global health policymakers. In addition, health programs should be provided to reduce the burden of this disease in the regions with high incidence and mortality rates of SC.

Global CLEWs model - A novel application of OSeMOSYS

NASA Astrophysics Data System (ADS)

Avgerinopoulos, Georgios; Pereira Ramos, Eunice; Howells, Mark

2017-04-01

Over the past years, studies that analyse Nexus issues from a holistic point of view and not energy, land or water separately have been gaining momentum. This project aims at giving insights into global issues through the application and the analysis of a global scale OSeMOSYS model. The latter -which is based on a fully open and amendable code- has been used successfully in the latest years as it has been the producing fully accessible energy models suitable for capacity building and policy making suggestions. This study develops a CLEWs (climate, land, energy and water) model with the objective of interrogating global challenges (e.g. increasing food demand) and international trade features, with policy priorities on food security, resource efficiency, low-carbon energy and climate change mitigation, water availability and vulnerability to water stress and floods, water quality, biodiversity and ecosystem services. It will for instance assess (i) the impact of water constraints on food security and human development (clean water for human use; industrial and energy water demands), as well as (ii) the impact of climate change on aggravating or relieving water problems.

Diagnosis of human fascioliasis by stool and blood techniques: update for the present global scenario.

PubMed

Mas-Coma, S; Bargues, M D; Valero, M A

2014-12-01

Before the 1990s, human fascioliasis diagnosis focused on individual patients in hospitals or health centres. Case reports were mainly from developed countries and usually concerned isolated human infection in animal endemic areas. From the mid-1990s onwards, due to the progressive description of human endemic areas and human infection reports in developing countries, but also new knowledge on clinical manifestations and pathology, new situations, hitherto neglected, entered in the global scenario. Human fascioliasis has proved to be pronouncedly more heterogeneous than previously thought, including different transmission patterns and epidemiological situations. Stool and blood techniques, the main tools for diagnosis in humans, have been improved for both patient and survey diagnosis. Present availabilities for human diagnosis are reviewed focusing on advantages and weaknesses, sample management, egg differentiation, qualitative and quantitative diagnosis, antibody and antigen detection, post-treatment monitoring and post-control surveillance. Main conclusions refer to the pronounced difficulties of diagnosing fascioliasis in humans given the different infection phases and parasite migration capacities, clinical heterogeneity, immunological complexity, different epidemiological situations and transmission patterns, the lack of a diagnostic technique covering all needs and situations, and the advisability for a combined use of different techniques, at least including a stool technique and a blood technique.

A Flexible Socioeconomic Scenarios Framework for the Study of Plausible Arctic Futures

NASA Astrophysics Data System (ADS)

Reissell, A. K.; Peters, G. P.; Riahi, K.; Kroglund, M.; Lovecraft, A. L.; Nilsson, A. E.; Preston, B. L.; van Ruijven, B. J.

2016-12-01

Future developments of the Arctic region are associated with different drivers of change - climate, environmental, and socio-economic - and their interactions, and are highly uncertain. The uncertainty poses challenges for decision-making, calling for development of new analytical frameworks. Scenarios - coherent narratives describing potential futures, pathways to futures, and drivers of change along the way - can be used to explore the consequences of the key uncertainties, particularly in the long-term. In a participatory scenarios workshop, we used both top-down and bottom-up approaches for the development of a flexible socioeconomic scenarios framework. The top-down approach was linked to the global Integrated Assessment Modeling framework and its Shared Socio-Economic Pathways (SSPs), developing an Arctic extension of the set of five storylines on the main socioeconomic uncertainties in global climate change research. The bottom-up approach included participatory development of narratives originating from within the Arctic region. For extension of global SSPs to the regional level, we compared the key elements in the global SSPs (Population, Human Development, Economy & Lifestyle, Policies & Institutions, Technology, and Environment & Natural Resources) and key elements in the Arctic. Additional key elements for the Arctic scenarios include, for example, seasonal migration, the large role of traditional knowledge and culture, mixed economy, nested governance structure, human and environmental security, quality of infrastructure. The bottom-up derived results suggested that the scenarios developed independent of the SSPs could be mapped back to the SSPs to demonstrate consistency with respect to representing similar boundary conditions. The two approaches are complimentary, as the top-down approach can be used to set the global socio-economic and climate boundary conditions, and the bottom-up approach providing the regional context. One key uncertainty and driving force is the demand for resources (global or regional) that was mapped against the role of governance as well as adaptive and transformative capacity among actors within the Arctic. Resources demand has significant influence on the society, culture, economy and environment of the Arctic.

[When history meets molecular medicine: molecular history of human tuberculosis].

PubMed

Ottini, Laura; Falchetti, Mario

2010-01-01

Tuberculosis represents one of the humankind's most socially devastating diseases. Despite a long history of medical research and the development of effective therapies, this disease remains a global health danger even in the 21st century. Tuberculosis may cause death but infected people with effective immunity may remain healthy for years, suggesting long-term host-pathogen co-existence. Because of its antiquity, a supposed association with human settlements and the tendency to leave typical lesions on skeletal and mummified remains, tuberculosis has been the object of intensive multidisciplinary studies, including paleo-pathological research. During the past 10 years molecular paleo-pathology developed as a new scientific discipline allowing the study of ancient pathogens by direct detection of their DNA. In this work, we reviewed evidences for tuberculosis in ancient human remains, current methods for identifying ancient mycobacterial DNA and explored current theories of Mycobacterium tuberculosis evolution and their implications in the global development of tuberculosis looking into the past and present at the same time.

Prospects for development of unified global flood observation and prediction systems (Invited)

NASA Astrophysics Data System (ADS)

Lettenmaier, D. P.

2013-12-01

Floods are among the most damaging of natural hazards, with global flood losses in 2011 alone estimated to have exceeded $100B. Historically, flood economic damages have been highest in the developed world (due in part to encroachment on historical flood plains), but loss of life, and human impacts have been greatest in the developing world. However, as the 2011 Thailand floods show, industrializing countries, many of which do not have well developed flood protection systems, are increasingly vulnerable to economic damages as they become more industrialized. At present, unified global flood observation and prediction systems are in their infancy; notwithstanding that global weather forecasting is a mature field. The summary for this session identifies two evolving capabilities that hold promise for development of more sophisticated global flood forecast systems: global hydrologic models and satellite remote sensing (primarily of precipitation, but also of flood inundation). To this I would add the increasing sophistication and accuracy of global precipitation analysis (and forecast) fields from numerical weather prediction models. In this brief overview, I will review progress in all three areas, and especially the evolution of hydrologic data assimilation which integrates modeling and data sources. I will also comment on inter-governmental and inter-agency cooperation, and related issues that have impeded progress in the development and utilization of global flood observation and prediction systems.

Renewed Global Partnerships and Redesigned Roadmaps for Rabies Prevention and Control

PubMed Central

Lembo, Tiziana; Attlan, Michaël; Bourhy, Hervé; Cleaveland, Sarah; Costa, Peter; de Balogh, Katinka; Dodet, Betty; Fooks, Anthony R.; Hiby, Elly; Leanes, Fernando; Meslin, François-Xavier; Miranda, Mary Elizabeth; Müller, Thomas; Nel, Louis H.; Rupprecht, Charles E.; Tordo, Noël; Tumpey, Abbigail; Wandeler, Alexander; Briggs, Deborah J.

2011-01-01

Canine rabies, responsible for most human rabies deaths, is a serious global public health concern. This zoonosis is entirely preventable, but by focusing solely upon rabies prevention in humans, this “incurable wound” persists at high costs. Although preventing human deaths through canine rabies elimination is feasible, dog rabies control is often neglected, because dogs are not considered typical economic commodities by the animal health sector. Here, we demonstrate that the responsibility of managing rabies falls upon multiple sectors, that a truly integrated approach is the key to rabies elimination, and that considerable progress has been made to this effect. Achievements include the construction of global rabies networks and organizational partnerships; development of road maps, operational toolkits, and a blueprint for rabies prevention and control; and opportunities for scaling up and replication of successful programs. Progress must continue towards overcoming the remaining challenges preventing the ultimate goal of rabies elimination. PMID:21776359

Modeling infectious disease dynamics in the complex landscape of global health.

PubMed

Heesterbeek, Hans; Anderson, Roy M; Andreasen, Viggo; Bansal, Shweta; De Angelis, Daniela; Dye, Chris; Eames, Ken T D; Edmunds, W John; Frost, Simon D W; Funk, Sebastian; Hollingsworth, T Deirdre; House, Thomas; Isham, Valerie; Klepac, Petra; Lessler, Justin; Lloyd-Smith, James O; Metcalf, C Jessica E; Mollison, Denis; Pellis, Lorenzo; Pulliam, Juliet R C; Roberts, Mick G; Viboud, Cecile

2015-03-13

Despite some notable successes in the control of infectious diseases, transmissible pathogens still pose an enormous threat to human and animal health. The ecological and evolutionary dynamics of infections play out on a wide range of interconnected temporal, organizational, and spatial scales, which span hours to months, cells to ecosystems, and local to global spread. Moreover, some pathogens are directly transmitted between individuals of a single species, whereas others circulate among multiple hosts, need arthropod vectors, or can survive in environmental reservoirs. Many factors, including increasing antimicrobial resistance, increased human connectivity and changeable human behavior, elevate prevention and control from matters of national policy to international challenge. In the face of this complexity, mathematical models offer valuable tools for synthesizing information to understand epidemiological patterns, and for developing quantitative evidence for decision-making in global health. Copyright © 2015, American Association for the Advancement of Science.

Institutionalizing human-computer interaction for global health

PubMed Central

Gulliksen, Jan

2017-01-01

ABSTRACT Digitalization is the societal change process in which new ICT-based solutions bring forward completely new ways of doing things, new businesses and new movements in the society. Digitalization also provides completely new ways of addressing issues related to global health. This paper provides an overview of the field of human-computer interaction (HCI) and in what way the field has contributed to international development in different regions of the world. Additionally, it outlines the United Nations’ new sustainability goals from December 2015 and what these could contribute to the development of global health and its relationship to digitalization. Finally, it argues why and how HCI could be adopted and adapted to fit the contextual needs, the need for localization and for the development of new digital innovations. The research methodology is mostly qualitative following an action research paradigm in which the actual change process that the digitalization is evoking is equally important as the scientific conclusions that can be drawn. In conclusion, the paper argues that digitalization is fundamentally changing the society through the development and use of digital technologies and may have a profound effect on the digital development of every country in the world. But it needs to be developed based on local practices, it needs international support and to not be limited by any technological constraints. Particularly digitalization to support global health requires a profound understanding of the users and their context, arguing for user-centred systems design methodologies as particularly suitable. PMID:28838309

Molecular and functional definition of the developing human striatum.

PubMed

Onorati, Marco; Castiglioni, Valentina; Biasci, Daniele; Cesana, Elisabetta; Menon, Ramesh; Vuono, Romina; Talpo, Francesca; Laguna Goya, Rocio; Lyons, Paul A; Bulfamante, Gaetano P; Muzio, Luca; Martino, Gianvito; Toselli, Mauro; Farina, Cinthia; Barker, Roger A; Biella, Gerardo; Cattaneo, Elena

2014-12-01

The complexity of the human brain derives from the intricate interplay of molecular instructions during development. Here we systematically investigated gene expression changes in the prenatal human striatum and cerebral cortex during development from post-conception weeks 2 to 20. We identified tissue-specific gene coexpression networks, differentially expressed genes and a minimal set of bimodal genes, including those encoding transcription factors, that distinguished striatal from neocortical identities. Unexpected differences from mouse striatal development were discovered. We monitored 36 determinants at the protein level, revealing regional domains of expression and their refinement, during striatal development. We electrophysiologically profiled human striatal neurons differentiated in vitro and determined their refined molecular and functional properties. These results provide a resource and opportunity to gain global understanding of how transcriptional and functional processes converge to specify human striatal and neocortical neurons during development.

Development of Time-Series Human Settlement Mapping System Using Historical Landsat Archive

NASA Astrophysics Data System (ADS)

Miyazaki, H.; Nagai, M.; Shibasaki, R.

2016-06-01

Methodology of automated human settlement mapping is highly needed for utilization of historical satellite data archives for urgent issues of urban growth in global scale, such as disaster risk management, public health, food security, and urban management. As development of global data with spatial resolution of 10-100 m was achieved by some initiatives using ASTER, Landsat, and TerraSAR-X, next goal has targeted to development of time-series data which can contribute to studies urban development with background context of socioeconomy, disaster risk management, public health, transport and other development issues. We developed an automated algorithm to detect human settlement by classification of built-up and non-built-up in time-series Landsat images. A machine learning algorithm, Local and Global Consistency (LLGC), was applied with improvements for remote sensing data. The algorithm enables to use MCD12Q1, a MODIS-based global land cover map with 500-m resolution, as training data so that any manual process is not required for preparation of training data. In addition, we designed the method to composite multiple results of LLGC into a single output to reduce uncertainty. The LLGC results has a confidence value ranging 0.0 to 1.0 representing probability of built-up and non-built-up. The median value of the confidence for a certain period around a target time was expected to be a robust output of confidence to identify built-up or non-built-up areas against uncertainties in satellite data quality, such as cloud and haze contamination. Four scenes of Landsat data for each target years, 1990, 2000, 2005, and 2010, were chosen among the Landsat archive data with cloud contamination less than 20%.We developed a system with the algorithms on the Data Integration and Analysis System (DIAS) in the University of Tokyo and processed 5200 scenes of Landsat data for cities with more than one million people worldwide.

Exploring the planetary boundary for chemical pollution.

PubMed

Diamond, Miriam L; de Wit, Cynthia A; Molander, Sverker; Scheringer, Martin; Backhaus, Thomas; Lohmann, Rainer; Arvidsson, Rickard; Bergman, Åke; Hauschild, Michael; Holoubek, Ivan; Persson, Linn; Suzuki, Noriyuki; Vighi, Marco; Zetzsch, Cornelius

2015-05-01

Rockström et al. (2009a, 2009b) have warned that humanity must reduce anthropogenic impacts defined by nine planetary boundaries if "unacceptable global change" is to be avoided. Chemical pollution was identified as one of those boundaries for which continued impacts could erode the resilience of ecosystems and humanity. The central concept of the planetary boundary (or boundaries) for chemical pollution (PBCP or PBCPs) is that the Earth has a finite assimilative capacity for chemical pollution, which includes persistent, as well as readily degradable chemicals released at local to regional scales, which in aggregate threaten ecosystem and human viability. The PBCP allows humanity to explicitly address the increasingly global aspects of chemical pollution throughout a chemical's life cycle and the need for a global response of internationally coordinated control measures. We submit that sufficient evidence shows stresses on ecosystem and human health at local to global scales, suggesting that conditions are transgressing the safe operating space delimited by a PBCP. As such, current local to global pollution control measures are insufficient. However, while the PBCP is an important conceptual step forward, at this point single or multiple PBCPs are challenging to operationalize due to the extremely large number of commercial chemicals or mixtures of chemicals that cause myriad adverse effects to innumerable species and ecosystems, and the complex linkages between emissions, environmental concentrations, exposures and adverse effects. As well, the normative nature of a PBCP presents challenges of negotiating pollution limits amongst societal groups with differing viewpoints. Thus, a combination of approaches is recommended as follows: develop indicators of chemical pollution, for both control and response variables, that will aid in quantifying a PBCP(s) and gauging progress towards reducing chemical pollution; develop new technologies and technical and social approaches to mitigate global chemical pollution that emphasize a preventative approach; coordinate pollution control and sustainability efforts; and facilitate implementation of multiple (and potentially decentralized) control efforts involving scientists, civil society, government, non-governmental organizations and international bodies. Copyright © 2015 Elsevier Ltd. All rights reserved.

Perspectives on the global threat: the challenge of avian influenza viruses for the world's veterinary community.

PubMed

Capua, Ilaria; Alexander, Dennis

2010-03-01

The ongoing animal and human health crises caused by influenza viruses of H5N1 subtype have focused the attention of international organizations and donors on the need for improved veterinary infrastructure in developing countries and the need for improved communication between the human and animal health sectors. The circulation and re-emergence of high-pathogenicity avian influenza viruses of H5N1 subtype are still major concerns because of potential effects on human health, on the profitability of poultry industries, and on the livelihood of the rural environment. Significant improvements toward the management of these outbreaks have occurred worldwide, including new legislative tools, intervention strategies, and investments in capacity building in both developed and developing countries. This has led to a greater understanding of certain aspects of this infection and of its pandemic potential, although we are still far from certainties and from resolving the situation. Given that genetic analysis of the viruses causing human pandemics since the beginning of the 20th century have indicated that at least the hemagglutinin gene was donated from an avian progenitor virus, it would seem reasonable to exploit the information we have from an animal health perspective to support public health policies. Possibly the biggest challenge we have is to find novel ways to maximize the use of the information that is generated as a result of the improved networking and diagnostic capacities. In the era of globalization, emerging and re-emerging diseases of public health relevance are a concern to developing and developed countries and are a real threat because of the interdependence of the global economy. Communication and analysis systems currently available should be tailored to meet global health priorities, and used to develop and constantly improve novel systems for the exploitation of information to generate knowledge. Another fundamental task the veterinary community needs to deliver on is that of bringing relevant information to international discussion tables at which international control and prevention are presented and optimized. The veterinary community has knowledge and areas of expertise that should undoubtedly be part of strategic decisions and are essential to manage the human and animal health implications of avian influenza infections.

The Earth’s Population Can Reach 14 Billion in the 23rd Century without Significant Adverse Effects on Survivability

PubMed Central

Krapivin, Vladimir F.; Varotsos, Costas A.; Soldatov, Vladimir Yu.

2017-01-01

This paper presents the results obtained from the study of the sustainable state between nature and human society on a global scale, focusing on the most critical interactions between the natural and anthropogenic processes. Apart from the conventional global models, the basic tool employed herein is the newly proposed complex model entitled “nature-society system (NSS) model”, through which a reliable modeling of the processes taking place in the global climate-nature-society system (CNSS) is achieved. This universal tool is mainly based on the information technology that allows the adaptive conformance of the parametric and functional space of this model. The structure of this model includes the global biogeochemical cycles, the hydrological cycle, the demographic processes and a simple climate model. In this model, the survivability indicator is used as a criterion for the survival of humanity, which defines a trend in the dynamics of the total biomass of the biosphere, taking into account the trends of the biocomplexity dynamics of the land and hydrosphere ecosystems. It should be stressed that there are no other complex global models comparable to those of the CNSS model developed here. The potential of this global model is demonstrated through specific examples in which the classification of the terrestrial ecosystem is accomplished by separating 30 soil-plant formations for geographic pixels 4° × 5°. In addition, humanity is considered to be represented by three groups of economic development status (high, transition, developing) and the World Ocean is parameterized by three latitude zones (low, middle, high). The modelling results obtained show the dynamics of the CNSS at the beginning of the 23rd century, according to which the world population can reach the level of 14 billion without the occurrence of major negative impacts. PMID:28783136

Identification of Odorant-Receptor Interactions by Global Mapping of the Human Odorome

PubMed Central

Audouze, Karine; Tromelin, Anne; Le Bon, Anne Marie; Belloir, Christine; Petersen, Rasmus Koefoed; Kristiansen, Karsten; Brunak, Søren; Taboureau, Olivier

2014-01-01

The human olfactory system recognizes a broad spectrum of odorants using approximately 400 different olfactory receptors (hORs). Although significant improvements of heterologous expression systems used to study interactions between ORs and odorant molecules have been made, screening the olfactory repertoire of hORs remains a tremendous challenge. We therefore developed a chemical systems level approach based on protein-protein association network to investigate novel hOR-odorant relationships. Using this new approach, we proposed and validated new bioactivities for odorant molecules and OR2W1, OR51E1 and OR5P3. As it remains largely unknown how human perception of odorants influence or prevent diseases, we also developed an odorant-protein matrix to explore global relationships between chemicals, biological targets and disease susceptibilities. We successfully experimentally demonstrated interactions between odorants and the cannabinoid receptor 1 (CB1) and the peroxisome proliferator-activated receptor gamma (PPARγ). Overall, these results illustrate the potential of integrative systems chemical biology to explore the impact of odorant molecules on human health, i.e. human odorome. PMID:24695519

Ayahuasca and human destiny.

PubMed

McKenna, Dennis J

2005-06-01

In this essay, the author shares his personal reflections gleaned from a lifetime of research with ayahuasca, and speculates on the societal, political, planetary, and evolutionary implications of humanity's aeons-old symbiosis with this shamanic plant. The thesis is developed that at this critical historical juncture, ayahuasca has developed a strategy to broadcast its message to a wider world--a reflection of the urgent need to avert global ecological catastrophe. While ayahuasca has much to teach us, the critical question is, will humanity hear it, and heed it, in time?

An analysis of human-induced land transformations in the San Francisco Bay/Sacramento area

USGS Publications Warehouse

Kirtland, David A.; Gaydos, L.J.; Clarke, Keith; DeCola, Lee; Acevedo, William; Bell, Cindy

1994-01-01

Part of the U.S. Geological Survey's Global Change Research Program involvesstudying the area from the Pacific Ocean to the Sierra foothills to enhance understanding ofthe role that human activities play in global change. The study investigates the ways thathumans transform the land and the effects that changing the landscape may have on regionaland global systems. To accomplish this research, scientists are compiling records ofhistorical transformations in the region's land cover over the last 140 years, developing asimulation model to predict land cover change, and assembling a digital data set to analyzeand describe land transformations. The historical data regarding urban growth focusattention on the significant change the region underwent from 1850 to 1990. Animation isused to visualize a time series of the change in land cover. The historical change is beingused to calibrate a prototype cellular automata model, developed to predict changes in urbanland cover 100 years into the future. Future urban growth scenarios will be developed foranalyzing possible human-induced impacts on land cover at a regional scale. These data aidin documenting and understanding human-induced land transformations from both historical andpredictive perspectives. A descriptive analysis of the region is used to investigate therelationships among data characteristic of the region. These data consist of multilayertopography, climate, vegetation, and population data for a 256-km2 region of centralCalifornia. A variety of multivariate analysis tools are used to integrate the data inraster format from map contours, interpolated climate observations, satellite observations,and population estimates.

Towards a Framework Convention on Global Health: a transformative agenda for global health justice.

PubMed

Gostin, Lawrence O; Friedman, Eric A

2013-01-01

Global health inequities cause nearly 20 million deaths annually, mostly among the world's poor. Yet international law currently does little to reduce the massive inequalities that underlie these deaths. This Article offers the first systematic account of the goals and justifications, normative foundations, and potential construction of a proposed new global health treaty, a Framework Convention on Global Health (FCGH), grounded in the human right to health. Already endorsed by the United Nations Secretary-General, the FCGH would reimagine global governance for health, offering a new, post-Millennium Development Goals vision. A global coalition of civil society and academics has formed the Joint Action and Learning Initiative on National and Global Responsibilities for Health (JALI) to advance the FCGH.

Can Education for Sustainable Development Address Challenges in the Arab Region? Examining Business Students' Attitudes and Competences on Education for Sustainable Development: A Case Study

ERIC Educational Resources Information Center

Kanbar, Nancy

2012-01-01

The population growth together with the unsustainable consumption pattern is putting increasing stress on the planet's natural resources. The increasing realisation that humans are harming the environment is taking the form of a global movement intended to change behaviour towards sustainability, now recognised as a framework that links humans to…

The disease of corruption: views on how to fight corruption to advance 21st century global health goals.

PubMed

Mackey, Tim K; Kohler, Jillian Clare; Savedoff, William D; Vogl, Frank; Lewis, Maureen; Sale, James; Michaud, Joshua; Vian, Taryn

2016-09-29

Corruption has been described as a disease. When corruption infiltrates global health, it can be particularly devastating, threatening hard gained improvements in human and economic development, international security, and population health. Yet, the multifaceted and complex nature of global health corruption makes it extremely difficult to tackle, despite its enormous costs, which have been estimated in the billions of dollars. In this forum article, we asked anti-corruption experts to identify key priority areas that urgently need global attention in order to advance the fight against global health corruption. The views shared by this multidisciplinary group of contributors reveal several fundamental challenges and allow us to explore potential solutions to address the unique risks posed by health-related corruption. Collectively, these perspectives also provide a roadmap that can be used in support of global health anti-corruption efforts in the post-2015 development agenda.

The Geneva University Global Health and Human Rights Summer School: A 5-Year Intercultural Collaborative Experience

PubMed Central

Chastonay, Philippe; Mpinga, Emmanuel K.

2018-01-01

Education and training in human rights has been set as a priority by the United Nations. Health and human rights are closely related. Training professionals from various backgrounds in human rights might ultimately contribute to improve the health of individuals and communities. We present the 5 years’ experience with a 3-week residential Global Health and Human Rights Course developed at the University of Geneva and implemented with the support/participation of international organizations (IOs) and non-governmental organizations active in the health and human rights sector. Over the years, roughly 150 students from 43 nationalities, with many different educational backgrounds, attended the course. The male/female ratio was 1/5. The adopted educational approach was multifold and comprised lectures from academics and experts with field experience, group work, individual case studies, journal clubs, and site visits. Evaluation data show that site visits at IOs were highly appreciated as well as networking opportunities among students, with academics and experts with field experience. The variety of topics discussed was, at times, “too much”; yet, it allowed students to measure the extent of the challenges the field is facing. The adopted active learning approach facilitated the exchange of experiences among students and allowed them to get acquainted with different cultural sensitivities. The Global Health and Human Rights Summer-School of the University of Geneva allowed its participants, coming from all over the world, to identify challenges of the interlinked fields of health and human rights, reflect upon their underlying causes, and imagine possible solutions. Sharing our experience will hopefully help passionate educators around the world to develop similar programs. PMID:29868537

Multinational corporations and infectious disease: Embracing human rights management techniques.

PubMed

Salcito, Kendyl; Singer, Burton H; Weiss, Mitchell G; Winkler, Mirko S; Krieger, Gary R; Wielga, Mark; Utzinger, Jürg

2014-01-01

Global health institutions have called for governments, international organisations and health practitioners to employ a human rights-based approach to infectious diseases. The motivation for a human rights approach is clear: poverty and inequality create conditions for infectious diseases to thrive, and the diseases, in turn, interact with social-ecological systems to promulgate poverty, inequity and indignity. Governments and intergovernmental organisations should be concerned with the control and elimination of these diseases, as widespread infections delay economic growth and contribute to higher healthcare costs and slower processes for realising universal human rights. These social determinants and economic outcomes associated with infectious diseases should interest multinational companies, partly because they have bearing on corporate productivity and, increasingly, because new global norms impose on companies a responsibility to respect human rights, including the right to health. We reviewed historical and recent developments at the interface of infectious diseases, human rights and multinational corporations. Our investigation was supplemented with field-level insights at corporate capital projects that were developed in areas of high endemicity of infectious diseases, which embraced rights-based disease control strategies. Experience and literature provide a longstanding business case and an emerging social responsibility case for corporations to apply a human rights approach to health programmes at global operations. Indeed, in an increasingly globalised and interconnected world, multinational corporations have an interest, and an important role to play, in advancing rights-based control strategies for infectious diseases. There are new opportunities for governments and international health agencies to enlist corporate business actors in disease control and elimination strategies. Guidance offered by the United Nations in 2011 that is widely embraced by companies, governments and civil society provides a roadmap for engaging business enterprises in rights-based disease management strategies to mitigate disease transmission rates and improve human welfare outcomes.

The Geneva University Global Health and Human Rights Summer School: A 5-Year Intercultural Collaborative Experience.

PubMed

Chastonay, Philippe; Mpinga, Emmanuel K

2018-01-01

Education and training in human rights has been set as a priority by the United Nations. Health and human rights are closely related. Training professionals from various backgrounds in human rights might ultimately contribute to improve the health of individuals and communities. We present the 5 years' experience with a 3-week residential Global Health and Human Rights Course developed at the University of Geneva and implemented with the support/participation of international organizations (IOs) and non-governmental organizations active in the health and human rights sector. Over the years, roughly 150 students from 43 nationalities, with many different educational backgrounds, attended the course. The male/female ratio was 1/5. The adopted educational approach was multifold and comprised lectures from academics and experts with field experience, group work, individual case studies, journal clubs, and site visits. Evaluation data show that site visits at IOs were highly appreciated as well as networking opportunities among students, with academics and experts with field experience. The variety of topics discussed was, at times, "too much"; yet, it allowed students to measure the extent of the challenges the field is facing. The adopted active learning approach facilitated the exchange of experiences among students and allowed them to get acquainted with different cultural sensitivities. The Global Health and Human Rights Summer-School of the University of Geneva allowed its participants, coming from all over the world, to identify challenges of the interlinked fields of health and human rights, reflect upon their underlying causes, and imagine possible solutions. Sharing our experience will hopefully help passionate educators around the world to develop similar programs.

An analysis of GAVI, the Global Fund and World Bank support for human resources for health in developing countries.

PubMed

Vujicic, Marko; Weber, Stephanie E; Nikolic, Irina A; Atun, Rifat; Kumar, Ranjana

2012-12-01

Shortages, geographic imbalances and poor performance of health workers pose major challenges for improving health service delivery in developing countries. In response, multilateral agencies have increasingly recognized the need to invest in human resources for health (HRH) to assist countries in achieving their health system goals. In this paper we analyse the HRH-related activities of three agencies: the Global Alliance for Vaccines and Immunisation (GAVI); the Global Fund for Aids, Tuberculosis, and Malaria (the Global Fund); and the World Bank. First, we reviewed the type of HRH-related activities that are eligible for financing within each agency. Second, we reviewed the HRH-related activities that each agency is actually financing. Third, we reviewed the literature to understand the impact that GAVI, Global Fund and World Bank investments in HRH have had on the health workforce in developing countries. Our analysis found that by far the most common activity supported across all agencies is short-term, in-service training. There is relatively little investment in expanding pre-service training capacity, despite large health worker shortages in developing countries. We also found that the majority of GAVI and the Global Fund grants finance health worker remuneration, largely through supplemental allowances, with little information available on how payment rates are determined, how the potential negative consequences are mitigated, and how payments are to be sustained at the end of the grant period. Based on the analysis, we argue there is an opportunity for improved co-ordination between the three agencies at the country level in supporting HRH-related activities. Existing initiatives, such as the International Health Partnership and the Health Systems Funding Platform, could present viable and timely vehicles for the three agencies to implement this improved co-ordination.

Towards integrated solutions for water, energy, and land using an integrated nexus modeling framework

NASA Astrophysics Data System (ADS)

Wada, Y.

2017-12-01

Humanity has already reached or even exceeded the Earth's carrying capacity. Growing needs for food, energy and water will only exacerbate existing challenges over the next decades. Consequently, the acceptance of "business as usual" is eroding and we are being challenged to adopt new, more integrated, and more inclusive development pathways that avoid dangerous interference with the local environment and global planetary boundaries. This challenge is embodied in the United Nation's Sustainable Development Goals (SDGs), which endeavor to set a global agenda for moving towards more sustainable development strategies. To improve and sustain human welfare, it is critical that access to modern, reliable, and affordable water, energy, and food is expanded and maintained. The Integrated Solutions for Water, Energy, and Land (IS-WEL) project has been launched by IIASA, together with the Global Environment Facility (GEF) and the United Nations Industrial Development Organization (UNIDO). This project focuses on the water-energy-land nexus in the context of other major global challenges such as urbanization, environmental degradation, and equitable and sustainable futures. It develops a consistent framework for looking at the water-energy-land nexus and identify strategies for achieving the needed transformational outcomes through an advanced assessment framework. A multi-scalar approach are being developed that aims to combine global and regional integrated assessment tools with local stakeholder knowledge in order to identify robust solutions to energy, water, food, and ecosystem security in selected regions of the world. These are regions facing multiple energy, water and land use challenges and rapid demographic and economic changes, and are hardest hit by increasing climate variability and change. This project combines the global integrated assessment model (MESSAGE) with the global land (GLOBIOM) and water (Community Water Model) model respectively, and the integrated modeling framework are then combined with detailed regional decision support tools for water-energy-land nexus analysis in case study regions. A number of stakeholder meetings are used to engage local communities in the definition of important nexus drivers, scenario development and definition of performance metrics.

Study of Global Health Strategy Based on International Trends

PubMed Central

HATANAKA, Takashi; EGUCHI, Narumi; DEGUCHI, Mayumi; YAZAWA, Manami; ISHII, Masami

2015-01-01

The Japanese government at present is implementing international health and medical growth strategies mainly from the viewpoint of business. However, the United Nations is set to resolve the Post-2015 Development Agenda in the fall of 2015; the agenda will likely include the achievement of universal health coverage (UHC) as a specific development goal. Japan’s healthcare system, the foundation of which is its public, nationwide universal health insurance program, has been evaluated highly by the Lancet. The World Bank also praised it as a global model. This paper presents suggestions and problems for Japan regarding global health strategies, including in regard to several prerequisite domestic preparations that must be made. They are summarized as follows. (1) The UHC development should be promoted in coordination with the United Nations, World Bank, and Asian Development Bank. (2) The universal health insurance system of Japan can be a global model for UHC and ensuring its sustainability should be considered a national policy. (3) Trade agreements such as the Trans-Pacific Partnership (TPP) should not disrupt or interfere with UHC, the form of which is unique to each nation, including Japan. (4) Japan should disseminate information overseas, including to national governments, people, and physicians, regarding the course of events that led to the establishment of the Japan’s universal health insurance system and should make efforts to develop international human resources to participate in UHC policymaking. (5) The development of separate healthcare programs and UHC preparation should be promoted by streamlining and centralizing maternity care, school health, infectious disease management such as for tuberculosis, and emergency medicine such as for traffic accidents. (6) Japan should disseminate information overseas about its primary care physicians (kakaritsuke physicians) and develop international human resources. (7) Global health should be developed in integration with global environment problem management. (8) Support systems, such as for managing large-scale disasters of international scale or preventing the spread of infectious diseases, should be developed and maintained. (9) International healthcare policy, which the Japanese government is trying to promote in accordance with international trends, and international development of Japanese healthcare industry should be reconsidered. PMID:26870622

Predictive global trends in the incidence and mortality of pancreatic cancer based on geographic location, socio-economic status, and demographic shift.

PubMed

Are, Chandrakanth; Chowdhury, Sanjib; Ahmad, Humera; Ravipati, Advaitaa; Song, Tianqiang; Shrikandhe, Shailesh; Smith, Lynette

2016-11-01

Pancreatic Cancer (PC) is a lethal malignancy that accounts for about 4% of cancer-related deaths worldwide. The aim of this study is to describe the influence of geography (based on WHO regions), socio-economic development (based on Human Development Index [HDI]) and demographic shift on the temporal trends in global incidence and mortality of PC. Data (2012-2030) relating to the incidence, mortality of PC and demographic shifts based on WHO regions and HDI areas were extracted from GLOBOCAN 2012. Linear regression was used to evaluate trends in total incidence and mortality. We noted a definite association between PC and higher socio-economic status. Advanced age (age ≥65) contributed to the rising burden in all socio-economic regions of the world except in the Low Human Development (LHD) countries where the disease predominantly affected population <65 years of age. The global burden of PC is expected to rise significantly over the next few decades regardless of geographic location, socio-economic development, age and gender. Advance knowledge of this data can help formulate strategies to specifically target countries and populations that promote public health policy to tackle this lethal disease on the global stage. J. Surg. Oncol. 2016;114:736-742. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Methods to achieve accurate projection of regional and global raster databases

USGS Publications Warehouse

Usery, E. Lynn; Seong, Jeong Chang; Steinwand, Dan

2002-01-01

Modeling regional and global activities of climatic and human-induced change requires accurate geographic data from which we can develop mathematical and statistical tabulations of attributes and properties of the environment. Many of these models depend on data formatted as raster cells or matrices of pixel values. Recently, it has been demonstrated that regional and global raster datasets are subject to significant error from mathematical projection and that these errors are of such magnitude that model results may be jeopardized (Steinwand, et al., 1995; Yang, et al., 1996; Usery and Seong, 2001; Seong and Usery, 2001). There is a need to develop methods of projection that maintain the accuracy of these datasets to support regional and global analyses and modeling

Emerging and reemerging neglected tropical diseases: a review of key characteristics, risk factors, and the policy and innovation environment.

PubMed

Mackey, Tim K; Liang, Bryan A; Cuomo, Raphael; Hafen, Ryan; Brouwer, Kimberly C; Lee, Daniel E

2014-10-01

In global health, critical challenges have arisen from infectious diseases, including the emergence and reemergence of old and new infectious diseases. Emergence and reemergence are accelerated by rapid human development, including numerous changes in demographics, populations, and the environment. This has also led to zoonoses in the changing human-animal ecosystem, which are impacted by a growing globalized society where pathogens do not recognize geopolitical borders. Within this context, neglected tropical infectious diseases have historically lacked adequate attention in international public health efforts, leading to insufficient prevention and treatment options. This subset of 17 infectious tropical diseases disproportionately impacts the world's poorest, represents a significant and underappreciated global disease burden, and is a major barrier to development efforts to alleviate poverty and improve human health. Neglected tropical diseases that are also categorized as emerging or reemerging infectious diseases are an even more serious threat and have not been adequately examined or discussed in terms of their unique risk characteristics. This review sets out to identify emerging and reemerging neglected tropical diseases and explore the policy and innovation environment that could hamper or enable control efforts. Through this examination, we hope to raise awareness and guide potential approaches to addressing this global health concern. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

International perspectives on the ethics and regulation of human cell and tissue transplantation.

PubMed

Schulz-Baldes, Annette; Biller-Andorno, Nikola; Capron, Alexander Morgan

2007-12-01

The transplantation of human cells and tissues has become a global enterprise for both life-saving and life-enhancing purposes. Yet current practices raise numerous ethical and policy issues relating to informed consent for donation, profit-making, and quality and safety in the procurement, processing, distribution, and international circulation of human cells and tissues. This paper reports on recent developments in the international debate surrounding these issues, and in particular on the attention cell and tissue transplantation has received in WHO's ongoing process of updating its 1991 Guiding principles on human organ transplantation. Several of the organizers of an international working group of stakeholders from a wide range of backgrounds that convened in Zurich in July 2006 summarize the areas of normative agreement and disagreement, and identify open questions regarding facts and fundamental concepts of potential normative significance. These issues must be addressed through development of common medical, scientific, legal and ethical requirements for human cell and tissue transplantation on a global basis. While guidance must accommodate the distinct ethical issues raised by activities involving human cells and tissues, consistency with normative frameworks for organ transplantation remains a prime objective.

Space life and biomedical sciences in support of the global exploration roadmap and societal development

NASA Astrophysics Data System (ADS)

Evetts, S. N.

2014-08-01

The human exploration of space is pushing the boundaries of what is technically feasible. The space industry is preparing for the New Space era, the momentum for which will emanate from the commercial human spaceflight sector, and will be buttressed by international solar system exploration endeavours. With many distinctive technical challenges to be overcome, human spaceflight requires that numerous biological and physical systems be examined under exceptional circumstances for progress to be made. To effectively tackle such an undertaking significant intra- and international coordination and collaboration is required. Space life and biomedical science research and development (R & D) will support the Global Exploration Roadmap (GER) by enabling humans to 'endure' the extreme activity that is long duration human spaceflight. In so doing the field will discover solutions to some of our most difficult human health issues, and as a consequence benefit society as a whole. This space-specific R&D will drive a significant amount of terrestrial biomedical research and as a result the international community will not only gain benefits in the form of improved healthcare in space and on Earth, but also through the growth of its science base and industry.

23 CFR 450.306 - Scope of the metropolitan transportation planning process.

Code of Federal Regulations, 2010 CFR

2010-04-01

...: (1) Support the economic vitality of the metropolitan area, especially by enabling global... transportation improvements and State and local planned growth and economic development patterns; (6) Enhance the... transportation system development, land use, employment, economic development, human and natural environment, and...

Global Migration Dynamics Underlie Evolution and Persistence of Human Influenza A (H3N2)

PubMed Central

Bedford, Trevor; Cobey, Sarah; Beerli, Peter; Pascual, Mercedes

2010-01-01

The global migration patterns of influenza viruses have profound implications for the evolutionary and epidemiological dynamics of the disease. We developed a novel approach to reconstruct the genetic history of human influenza A (H3N2) collected worldwide over 1998 to 2009 and used it to infer the global network of influenza transmission. Consistent with previous models, we find that China and Southeast Asia lie at the center of this global network. However, we also find that strains of influenza circulate outside of Asia for multiple seasons, persisting through dynamic migration between northern and southern regions. The USA acts as the primary hub of temperate transmission and, together with China and Southeast Asia, forms the trunk of influenza's evolutionary tree. These findings suggest that antiviral use outside of China and Southeast Asia may lead to the evolution of long-term local and potentially global antiviral resistance. Our results might also aid the design of surveillance efforts and of vaccines better tailored to different geographic regions. PMID:20523898

Challenges and opportunities for animal conservation from renewable energy development

Treesearch

T.A. Katzner; J.A. Johnson; D.M. Evans; T.W.J. Garner; M.E. Gompper; R. Altwegg; T.A. Branch; I.J. Gordon; N. Pettorelli

2013-01-01

Global climate change is among the greatest threats confronting both human and natural systems (IPCC, 2007). A substantial component of greenhouse gas (GHG) emissions is from energy production, generated via the burning of fossil fuels, especially coal, natural gas and refined petroleum. Given that reduction in global energy consumption is unlikely over the next...

Cancer Care and Control as a Human Right: Recognizing Global Oncology as an Academic Field.

PubMed

Eniu, Alexandru E; Martei, Yehoda M; Trimble, Edward L; Shulman, Lawrence N

2017-01-01

The global burden of cancer incidence and mortality is on the rise. There are major differences in cancer fatality rates due to profound disparities in the burden and resource allocation for cancer care and control in developed compared with developing countries. The right to cancer care and control should be a human right accessible to all patients with cancer, regardless of geographic or economic region, to avoid unnecessary deaths and suffering from cancer. National cancer planning should include an integrated approach that incorporates a continuum of education, prevention, cancer diagnostics, treatment, survivorship, and palliative care. Global oncology as an academic field should offer the knowledge and skills needed to efficiently assess situations and work on solutions, in close partnership. We need medical oncologists, surgical oncologists, pediatric oncologists, gynecologic oncologists, radiologists, and pathologists trained to think about well-tailored resource-stratified solutions to cancer care in the developing world. Moreover, the multidisciplinary fundamental team approach needed to treat most neoplastic diseases requires coordinated investment in several areas. Current innovative approaches have relied on partnerships between academic institutions in developed countries and local governments and ministries of health in developing countries to provide the expertise needed to implement effective cancer control programs. Global oncology is a viable and necessary field that needs to be emphasized because of its critical role in proposing not only solutions in developing countries, but also solutions that can be applied to similar challenges of access to cancer care and control faced by underserved populations in developed countries.

Framing health and foreign policy: lessons for global health diplomacy.

PubMed

Labonté, Ronald; Gagnon, Michelle L

2010-08-22

Global health financing has increased dramatically in recent years, indicative of a rise in health as a foreign policy issue. Several governments have issued specific foreign policy statements on global health and a new term, global health diplomacy, has been coined to describe the processes by which state and non-state actors engage to position health issues more prominently in foreign policy decision-making. Their ability to do so is important to advancing international cooperation in health. In this paper we review the arguments for health in foreign policy that inform global health diplomacy. These are organized into six policy frames: security, development, global public goods, trade, human rights and ethical/moral reasoning. Each of these frames has implications for how global health as a foreign policy issue is conceptualized. Differing arguments within and between these policy frames, while overlapping, can also be contradictory. This raises an important question about which arguments prevail in actual state decision-making. This question is addressed through an analysis of policy or policy-related documents and academic literature pertinent to each policy framing with some assessment of policy practice. The reference point for this analysis is the explicit goal of improving global health equity. This goal has increasing national traction within national public health discourse and decision-making and, through the Millennium Development Goals and other multilateral reports and declarations, is entering global health policy discussion. Initial findings support conventional international relations theory that most states, even when committed to health as a foreign policy goal, still make decisions primarily on the basis of the 'high politics' of national security and economic material interests. Development, human rights and ethical/moral arguments for global health assistance, the traditional 'low politics' of foreign policy, are present in discourse but do not appear to dominate practice. While political momentum for health as a foreign policy goal persists, the framing of this goal remains a contested issue. The analysis offered in this article may prove helpful to those engaged in global health diplomacy or in efforts to have global governance across a range of sectoral interests pay more attention to health equity impacts.

Framing health and foreign policy: lessons for global health diplomacy

PubMed Central

2010-01-01

Global health financing has increased dramatically in recent years, indicative of a rise in health as a foreign policy issue. Several governments have issued specific foreign policy statements on global health and a new term, global health diplomacy, has been coined to describe the processes by which state and non-state actors engage to position health issues more prominently in foreign policy decision-making. Their ability to do so is important to advancing international cooperation in health. In this paper we review the arguments for health in foreign policy that inform global health diplomacy. These are organized into six policy frames: security, development, global public goods, trade, human rights and ethical/moral reasoning. Each of these frames has implications for how global health as a foreign policy issue is conceptualized. Differing arguments within and between these policy frames, while overlapping, can also be contradictory. This raises an important question about which arguments prevail in actual state decision-making. This question is addressed through an analysis of policy or policy-related documents and academic literature pertinent to each policy framing with some assessment of policy practice. The reference point for this analysis is the explicit goal of improving global health equity. This goal has increasing national traction within national public health discourse and decision-making and, through the Millennium Development Goals and other multilateral reports and declarations, is entering global health policy discussion. Initial findings support conventional international relations theory that most states, even when committed to health as a foreign policy goal, still make decisions primarily on the basis of the 'high politics' of national security and economic material interests. Development, human rights and ethical/moral arguments for global health assistance, the traditional 'low politics' of foreign policy, are present in discourse but do not appear to dominate practice. While political momentum for health as a foreign policy goal persists, the framing of this goal remains a contested issue. The analysis offered in this article may prove helpful to those engaged in global health diplomacy or in efforts to have global governance across a range of sectoral interests pay more attention to health equity impacts. PMID:20727211

Global trends in milk quality: implications for the Irish dairy industry

PubMed Central

2009-01-01

The quality of Irish agricultural product will become increasingly important with the ongoing liberalisation of international trade. This paper presents a review of the global and Irish dairy industries; considers the impact of milk quality on farm profitability, food processing and human health, examines global trends in quality; and explores several models that are successfully being used to tackle milk quality concerns. There is a growing global demand for dairy products, fuelled in part by growing consumer wealth in developing countries. Global dairy trade represents only 6.2% of global production and demand currently outstrips supply. Although the Irish dairy industry is small by global standards, approximately 85% of annual production is exported annually. It is also the world's largest producer of powdered infant formula. Milk quality has an impact on human health, milk processing and on-farm profitability. Somatic cell count (SCC) is a key measure of milk quality, with a SCC not exceeding 400,000 cells/ml (the EU milk quality standard) generally accepted as the international export standard. There have been ongoing improvements in milk quality among both established and emerging international suppliers. A number of countries have developed successful industry-led models to tackle milk quality concerns. Based on international experiences, it is likely that problems with effective translation of knowledge to practice, rather than incomplete knowledge per se, are the more important constraints to national progress towards improved milk quality. PMID:22081986

Deletion of Panx3 Prevents the Development of Surgically Induced Osteoarthritis

PubMed Central

Moon, Paxton M.; Penuela, Silvia; Barr, Kevin; Khan, Sami; Pin, Christopher L.; Welch, Ian; Attur, Mukundan; Abramson, Steven B.

2015-01-01

Osteoarthritis (OA) is a highly prevalent, disabling joint disease with no existing therapies to slow or halt its progression. Cartilage degeneration hallmarks OA pathogenesis, and pannexin 3 (Panx3), a member of a novel family of channel proteins, is upregulated during this process. The function of Panx3 remains poorly understood, but we consistently observed a strong increase in Panx3 immunostaining in OA lesions in both mice and humans. Here, we developed and characterized the first global and conditional Panx3 knockout mice to investigate the role of Panx3 in OA. Interestingly, global Panx3 deletion produced no overt phenotype and had no obvious effect on early skeletal development. Mice lacking Panx3 specifically in the cartilage and global Panx3 knockout mice were markedly resistant to the development of OA following destabilization of medial meniscus surgery. These data indicate a specific catabolic role of Panx3 in articular cartilage and identify Panx3 as a potential therapeutic target for OA. Lastly, while Panx1 has been linked to over a dozen human pathologies, this is the first in vivo evidence for a role of Panx3 in disease. PMID:26138248

Study of Global Health Strategy Based on International Trends: -Promoting Universal Health Coverage Globally and Ensuring the Sustainability of Japan's Universal Coverage of Health Insurance System: Problems and Proposals.

PubMed

Hatanaka, Takashi; Eguchi, Narumi; Deguchi, Mayumi; Yazawa, Manami; Ishii, Masami

2015-09-01

The Japanese government at present is implementing international health and medical growth strategies mainly from the viewpoint of business. However, the United Nations is set to resolve the Post-2015 Development Agenda in the fall of 2015; the agenda will likely include the achievement of universal health coverage (UHC) as a specific development goal. Japan's healthcare system, the foundation of which is its public, nationwide universal health insurance program, has been evaluated highly by the Lancet. The World Bank also praised it as a global model. This paper presents suggestions and problems for Japan regarding global health strategies, including in regard to several prerequisite domestic preparations that must be made. They are summarized as follows. (1) The UHC development should be promoted in coordination with the United Nations, World Bank, and Asian Development Bank. (2) The universal health insurance system of Japan can be a global model for UHC and ensuring its sustainability should be considered a national policy. (3) Trade agreements such as the Trans-Pacific Partnership (TPP) should not disrupt or interfere with UHC, the form of which is unique to each nation, including Japan. (4) Japan should disseminate information overseas, including to national governments, people, and physicians, regarding the course of events that led to the establishment of the Japan's universal health insurance system and should make efforts to develop international human resources to participate in UHC policymaking. (5) The development of separate healthcare programs and UHC preparation should be promoted by streamlining and centralizing maternity care, school health, infectious disease management such as for tuberculosis, and emergency medicine such as for traffic accidents. (6) Japan should disseminate information overseas about its primary care physicians (kakaritsuke physicians) and develop international human resources. (7) Global health should be developed in integration with global environment problem management. (8) Support systems, such as for managing large-scale disasters of international scale or preventing the spread of infectious diseases, should be developed and maintained. (9) International healthcare policy, which the Japanese government is trying to promote in accordance with international trends, and international development of Japanese healthcare industry should be reconsidered.

Issues and consequences of using nutrition to modulate the avian immune response

USDA-ARS?s Scientific Manuscript database

Combatting antimicrobial resistant bacteria is a high priority for both public health and agriculture in the United States and globally. Antibiotic use in animals and humans is considered a major risk factor in the development of antibiotic resistant bacteria in animals, humans, and the environment...

Host responses to mycobacterial infections: Spotlight on biomarker discovery to predict vaccine

USDA-ARS?s Scientific Manuscript database

The global spread of tuberculosis (TB) in animals and humans result in enormous economic. social and public health burdens. TB vaccine development in both humans and animals has produced a growing portfolio of candidates with potential applicability across species. However, the lack of understandin...

Attitudes towards globalization and cosmopolitanism: cultural diversity, personal consumption and the national economy.

PubMed

Woodward, Ian; Skrbis, Zlatko; Bean, Clive

2008-06-01

One of the widely accepted consequences of globalization is the development of individual outlooks, behaviours and feelings that transcend local and national boundaries. This has encouraged a re-assessment of important assumptions about the nature of community, personal attachment and belonging in the face of unprecedented opportunities for culture, identities and politics to shape, and be shaped by, global events and processes. Recently, the upsurge of interest in the concept of cosmopolitanism has provided a promising new framework for understanding the nexus between cosmopolitan dispositions and global interconnectedness across cultural, political and economic realms. Using data from a representative social survey of Australians this paper investigates the negotiation of belonging under the conditions of globalization. The data tap into attitudes and behaviours associated with a broad gamut of cosmopolitan traits in the domains of culture, consumption, human rights, citizenship, and international governance. They show how cosmopolitan outlooks are shaped by social structural factors, and how forms of identification with humanity and the globe are fractured by boundaries of self and others, threats and opportunities, and the value of things global and local.

Inadvertent Weather Modification in Urban Areas: Lessons for Global Climate Change.

NASA Astrophysics Data System (ADS)

Changnon, Stanley A.

1992-05-01

Large metropolitan areas in North America, home to 65% of the nation's population, have created major changes in their climates over the past 150 years. The rate and amount of the urban climate change approximate those being predicted globally using climate models. Knowledge of urban weather and climate modification holds lessons for the global climate change issue. First, adjustments to urban climate changes can provide guidance for adjusting to global change. A second lesson relates to the difficulty but underscores the necessity of providing scientifically credible proof of change within the noise of natural climatic variability. The evolution of understanding about how urban conditions influence weather reveals several unexpected outcomes, particularly relating to precipitation changes. These suggest that similar future surprises can be expected in a changed global climate, a third lesson. In-depth studies of how urban climate changes affected the hydrologic cycle, the regional economy, and human activities were difficult because of data problems, lack of impact methodology, and necessity for multi disciplinary investigations. Similar impact studies for global climate change will require diverse scientific talents and funding commitments adequate to measure the complexity of impacts and human adjustments. Understanding the processes whereby urban areas and other human activities have altered the atmosphere and changed clouds and precipitation regionally appears highly relevant to the global climate-change issue. Scientific and governmental policy development needs to recognize an old axiom that became evident in the studies of inadvertent urban and regional climate change and their behavioral implications: Think globally but act locally. Global climate change is an international issue, and the atmosphere must be treated globally. But the impacts and the will to act and adjust will occur regionally.

Energy efficiency as a unifying principle for human, environmental, and global health

PubMed Central

Fontana, Luigi; Atella, Vincenzo; Kammen, Daniel M

2013-01-01

A strong analogy exists between over/under consumption of energy at the level of the human body and of the industrial metabolism of humanity. Both forms of energy consumption have profound implications for human, environmental, and global health. Globally, excessive fossil-fuel consumption, and individually, excessive food energy consumption are both responsible for a series of interrelated detrimental effects, including global warming, extreme weather conditions, damage to ecosystems, loss of biodiversity, widespread pollution, obesity, cancer, chronic respiratory disease, and other lethal chronic diseases. In contrast, data show that the efficient use of energy—in the form of food as well as fossil fuels and other resources—is vital for promoting human, environmental, and planetary health and sustainable economic development. While it is not new to highlight how efficient use of energy and food can address some of the key problems our world is facing, little research and no unifying framework exists to harmonize these concepts of sustainable system management across diverse scientific fields into a single theoretical body. Insights beyond reductionist views of efficiency are needed to encourage integrated changes in the use of the world’s natural resources, with the aim of achieving a wiser use of energy, better farming systems, and healthier dietary habits. This perspective highlights a range of scientific-based opportunities for cost-effective pro-growth and pro-health policies while using less energy and natural resources. PMID:24555053

Energy efficiency as a unifying principle for human, environmental, and global health.

PubMed

Fontana, Luigi; Atella, Vincenzo; Kammen, Daniel M

2013-01-01

A strong analogy exists between over/under consumption of energy at the level of the human body and of the industrial metabolism of humanity. Both forms of energy consumption have profound implications for human, environmental, and global health. Globally, excessive fossil-fuel consumption, and individually, excessive food energy consumption are both responsible for a series of interrelated detrimental effects, including global warming, extreme weather conditions, damage to ecosystems, loss of biodiversity, widespread pollution, obesity, cancer, chronic respiratory disease, and other lethal chronic diseases. In contrast, data show that the efficient use of energy-in the form of food as well as fossil fuels and other resources-is vital for promoting human, environmental, and planetary health and sustainable economic development. While it is not new to highlight how efficient use of energy and food can address some of the key problems our world is facing, little research and no unifying framework exists to harmonize these concepts of sustainable system management across diverse scientific fields into a single theoretical body. Insights beyond reductionist views of efficiency are needed to encourage integrated changes in the use of the world's natural resources, with the aim of achieving a wiser use of energy, better farming systems, and healthier dietary habits. This perspective highlights a range of scientific-based opportunities for cost-effective pro-growth and pro-health policies while using less energy and natural resources.

Modelling water use in global hydrological models: review, challenges and directions

NASA Astrophysics Data System (ADS)

Bierkens, M. F.; de Graaf, I.; Wada, Y.; Wanders, N.; Van Beek, L. P.

2017-12-01

During the late 1980s and early 1990s, awareness of the shortage of global water resources lead to the first detailed global water resources assessments using regional statistics of water use and observations of meteorological and hydrological variables. Shortly thereafter, the first macroscale hydrological models (MHM) appeared. In these models, blue water (i.e., surface water and renewable groundwater) availability was calculated by accumulating runoff over a stream network and comparing it with population densities or with estimated water demand for agriculture, industry and households. In this talk we review the evolution of human impact modelling in global land models with a focus on global water resources, touching upon developments of the last 15 years: i.e. calculating human water scarcity; estimating groundwater depletion; adding dams and reservoirs; fully integrating water use (demand, withdrawal, consumption, return flow) in the hydrology; simulating the effects of land use change. We show example studies for each of these steps. We identify We identify major challenges that hamper the further development of integrated water resources modelling. Examples of these are: 1) simulating reservoir operations; 2) including local infrastructure and redistribution; 3) using the correct allocations rules; 4) projecting future water demand and water use. For each of these challenges we signify promising directions for further research.

Framing global health: the governance challenge.

PubMed

McInnes, Colin; Kamradt-Scott, Adam; Lee, Kelley; Reubi, David; Roemer-Mahler, Anne; Rushton, Simon; Williams, Owain David; Woodling, Marie

2012-01-01

With the emergence of global health comes governance challenges which are equally global in nature. This article identifies some of the initial limitations in analyses of global health governance (GHG) before discussing the focus of this special supplement: the framing of global health issues and the manner in which this impacts upon GHG. Whilst not denying the importance of material factors (such as resources and institutional competencies), the article identifies how issues can be framed in different ways, thereby creating particular pathways of response which in turn affect the potential for and nature of GHG. It also identifies and discusses the key frames operating in global health: evidence-based medicine, human rights, security, economics and development.

Sexual and reproductive health and human rights of women living with HIV: a global community survey

PubMed Central

Orza, Luisa; Welbourn, Alice; Bewley, Susan; Crone, Tyler; Vazquez, Marijo

2016-01-01

Abstract Objective To determine the sexual and reproductive health priorities of women living with human immunodeficiency virus (HIV) and to allow the values and preferences of such women to be considered in the development of new guidelines. Methods A core team created a global reference group of 14 women living with HIV and together they developed a global community online survey. The survey, which contained mandatory and optional questions, was based on an appreciative enquiry approach in which the life-cycle experiences of women living with HIV were investigated. The same set of questions was also used in focus group discussions led by the global reference group. Findings The study covered 945 women (832 in the survey and 113 in the focus groups) aged 15–72 years in 94 countries. Among the respondents to the optional survey questions, 89.0% (427/480) feared or had experienced gender-based violence, 56.7% (177/312) had had an unplanned pregnancy, 72.3% (227/314) had received advice on safe conception and 58.8% (489/832) had suffered poor mental health after they had discovered their HIV-positive status. Conclusion The sexual and reproductive health needs and rights of women living with HIV are complex and require a stronger response from the health sector. The online survey placed the voices of women living with HIV at the start of the development of new global guidelines. Although not possible in some contexts and populations, a similar approach would merit replication in the development of guidelines for many other health considerations. PMID:27034517

Sexual and reproductive health and human rights of women living with HIV: a global community survey.

PubMed

Narasimhan, Manjulaa; Orza, Luisa; Welbourn, Alice; Bewley, Susan; Crone, Tyler; Vazquez, Marijo

2016-04-01

To determine the sexual and reproductive health priorities of women living with human immunodeficiency virus (HIV) and to allow the values and preferences of such women to be considered in the development of new guidelines. A core team created a global reference group of 14 women living with HIV and together they developed a global community online survey. The survey, which contained mandatory and optional questions, was based on an appreciative enquiry approach in which the life-cycle experiences of women living with HIV were investigated. The same set of questions was also used in focus group discussions led by the global reference group. The study covered 945 women (832 in the survey and 113 in the focus groups) aged 15-72 years in 94 countries. Among the respondents to the optional survey questions, 89.0% (427/480) feared or had experienced gender-based violence, 56.7% (177/312) had had an unplanned pregnancy, 72.3% (227/314) had received advice on safe conception and 58.8% (489/832) had suffered poor mental health after they had discovered their HIV-positive status. The sexual and reproductive health needs and rights of women living with HIV are complex and require a stronger response from the health sector. The online survey placed the voices of women living with HIV at the start of the development of new global guidelines. Although not possible in some contexts and populations, a similar approach would merit replication in the development of guidelines for many other health considerations.

Rights to food with a human face in the global south.

PubMed

Rahim, Aminur

2011-01-01

This article seeks to dispel the popular myth surrounding the food crises which precipitated food riots in the global South in 2008. Arguing from a structural and historical perspective, the article suggests that global hunger is a deep-rooted crisis that is embedded in the social and structural variables associated within the nation-state that places a restraint on the self-regulating capacity of nation-states in the South. Internationalizing the food crisis, however, will do more harm to the south’s agricultural transformation and rural development. The article argues for integrated rural development that will increase output growth through an institutional, technological, and marketing strategy.

Globalizing queer? AIDS, homophobia and the politics of sexual identity in India

PubMed Central

Kole, Subir K

2007-01-01

Queerness is now global. Many emerging economies of the global South are experiencing queer mobilization and sexual identity politics raising fundamental questions of citizenship and human rights on the one hand; and discourses of nationalism, cultural identity, imperialism, tradition and family-values on the other. While some researchers argue that with economic globalization in the developing world, a Western, hegemonic notion of lesbian, gay, bisexual and transgender (LGBT) identity has been exported to traditional societies thereby destroying indigenous sexual cultures and diversities, other scholars do not consider globalization as a significant factor in global queer mobilization and sexual identity politics. This paper aims at exploring the debate around globalization and contemporary queer politics in developing world with special reference to India. After briefly tracing the history of sexual identity politics, this paper examines the process of queer mobilization in relation to emergence of HIV/AIDS epidemic and forces of neoliberal globalization. I argue that the twin-process of globalization and AIDS epidemic has significantly influenced the mobilization of queer communities, while simultaneously strengthening right wing "homophobic" discourses of heterosexist nationalism in India. PMID:17623106

Globalizing queer? AIDS, homophobia and the politics of sexual identity in India.

PubMed

Kole, Subir K

2007-07-11

Queerness is now global. Many emerging economies of the global South are experiencing queer mobilization and sexual identity politics raising fundamental questions of citizenship and human rights on the one hand; and discourses of nationalism, cultural identity, imperialism, tradition and family-values on the other. While some researchers argue that with economic globalization in the developing world, a Western, hegemonic notion of lesbian, gay, bisexual and transgender (LGBT) identity has been exported to traditional societies thereby destroying indigenous sexual cultures and diversities, other scholars do not consider globalization as a significant factor in global queer mobilization and sexual identity politics. This paper aims at exploring the debate around globalization and contemporary queer politics in developing world with special reference to India. After briefly tracing the history of sexual identity politics, this paper examines the process of queer mobilization in relation to emergence of HIV/AIDS epidemic and forces of neoliberal globalization. I argue that the twin-process of globalization and AIDS epidemic has significantly influenced the mobilization of queer communities, while simultaneously strengthening right wing "homophobic" discourses of heterosexist nationalism in India.

Health-related rehabilitation services: assessing the global supply of and need for human resources

PubMed Central

2011-01-01

Background Human resources for rehabilitation are often a neglected component of health services strengthening and health workforce development. This may be partly related to weaknesses in the available research and evidence to inform advocacy and programmatic strategies. The objective of this study was to quantitatively describe the global situation in terms of supply of and need for human resources for health-related rehabilitation services, as a basis for strategy development of the workforce in physical and rehabilitation medicine. Methods Data for assessing supply of and need for rehabilitative personnel were extracted and analyzed from statistical databases maintained by the World Health Organization and other national and international health information sources. Standardized classifications were used to enhance cross-national comparability of findings. Results Large differences were found across countries and regions between assessed need for services requiring health workers associated to physical and rehabilitation medicine against estimated supply of health personnel skilled in rehabilitation services. Despite greater need, low- and middle-income countries tended to report less availability of skilled health personnel, although the strength of the supply-need relationship varied across geographical and economic country groupings. Conclusion The evidence base on human resources for health-related rehabilitation services remains fragmented, the result of limited availability and use of quality, comparable data and information within and across countries. This assessment offered the first global baseline, intended to catalyze further research that can be translated into evidence to support human resources for rehabilitation policy and practice. PMID:22004560

Vitamin Deficiencies in Humans: Can Plant Science Help?[W

PubMed Central

Fitzpatrick, Teresa B.; Basset, Gilles J.C.; Borel, Patrick; Carrari, Fernando; DellaPenna, Dean; Fraser, Paul D.; Hellmann, Hanjo; Osorio, Sonia; Rothan, Christophe; Valpuesta, Victoriano; Caris-Veyrat, Catherine; Fernie, Alisdair R.

2012-01-01

The term vitamin describes a small group of organic compounds that are absolutely required in the human diet. Although for the most part, dependency criteria are met in developed countries through balanced diets, this is not the case for the five billion people in developing countries who depend predominantly on a single staple crop for survival. Thus, providing a more balanced vitamin intake from high-quality food remains one of the grandest challenges for global human nutrition in the coming decade(s). Here, we describe the known importance of vitamins in human health and current knowledge on their metabolism in plants. Deficits in developing countries are a combined consequence of a paucity of specific vitamins in major food staple crops, losses during crop processing, and/or overreliance on a single species as a primary food source. We discuss the role that plant science can play in addressing this problem and review successful engineering of vitamin pathways. We conclude that while considerable advances have been made in understanding vitamin metabolic pathways in plants, more cross-disciplinary approaches must be adopted to provide adequate levels of all vitamins in the major staple crops to eradicate vitamin deficiencies from the global population. PMID:22374394

Global rates of habitat loss and implications for amphibian conservation

USGS Publications Warehouse

Gallant, Alisa L.; Klaver, R.W.; Casper, G.S.; Lannoo, M.J.

2007-01-01

A large number of factors are known to affect amphibian population viability, but most authors agree that the principal causes of amphibian declines are habitat loss, alteration, and fragmentation. We provide a global assessment of land use dynamics in the context of amphibian distributions. We accomplished this by compiling global maps of amphibian species richness and recent rates of change in land cover, land use, and human population growth. The amphibian map was developed using a combination of published literature and digital databases. We used an ecoregion framework to help interpret species distributions across environmental, rather than political, boundaries. We mapped rates of land cover and use change with statistics from the World Resources Institute, refined with a global digital dataset on land cover derived from satellite data. Temporal maps of human population were developed from the World Resources Institute database and other published sources. Our resultant map of amphibian species richness illustrates that amphibians are distributed in an uneven pattern around the globe, preferring terrestrial and freshwater habitats in ecoregions that are warm and moist. Spatiotemporal patterns of human population show that, prior to the 20th century, population growth and spread was slower, most extensive in the temperate ecoregions, and largely exclusive of major regions of high amphibian richness. Since the beginning of the 20th century, human population growth has been exponential and has occurred largely in the subtropical and tropical ecoregions favored by amphibians. Population growth has been accompanied by broad-scale changes in land cover and land use, typically in support of agriculture. We merged information on land cover, land use, and human population growth to generate a composite map showing the rates at which humans have been changing the world. When compared with the map of amphibian species richness, we found that many of the regions of the earth supporting the richest assemblages of amphibians are currently undergoing the highest rates of landscape modification.

Human motion analysis with detection of subpart deformations

NASA Astrophysics Data System (ADS)

Wang, Juhui; Lorette, Guy; Bouthemy, Patrick

1992-06-01

One essential constraint used in 3-D motion estimation from optical projections is the rigidity assumption. Because of muscle deformations in human motion, this rigidity requirement is often violated for some regions on the human body. Global methods usually fail to bring stable solutions. This paper presents a model-based approach to combating the effect of muscle deformations in human motion analysis. The approach developed is based on two main stages. In the first stage, the human body is partitioned into different areas, where each area is consistent with a general motion model (not necessarily corresponding to a physical existing motion pattern). In the second stage, the regions are eliminated under the hypothesis that they are not induced by a specific human motion pattern. Each hypothesis is generated by making use of specific knowledge about human motion. A global method is used to estimate the 3-D motion parameters in basis of valid segments. Experiments based on a cycling motion sequence are presented.

Process-based model with flood control measures towards more realistic global flood modeling

NASA Astrophysics Data System (ADS)

Tang, Q.; Zhang, X.; Wang, Y.; Mu, M.; Lv, A.; Li, Z.

2017-12-01

In the profoundly human-influenced era, the Anthropocene, increased amount of land was developed in flood plains and many flood control measures were implemented to protect people and infrastructures placed in the flood-prone areas. These human influences (for example, dams and dykes) have altered peak streamflow and flood risk, and are already an integral part of flood. However, most of the process-based flood models have yet to taken into account the human influences. In this study, we used a hydrological model together with an advanced hydrodynamic model to assess flood risk at the Baiyangdian catchment. The Baiyangdian Lake is the largest shallow freshwater lake in North China, and it was used as a flood storage area in the past. A new development hub for the Beijing-Tianjin-Hebei economic triangle, namely the Xiongan new area, was recently established in the flood-prone area around the lake. The shuttle radar topography mission (SRTM) digital elevation model (DEMs) was used to parameterize the hydrodynamic model simulation, and the inundation estimates were compared with published flood maps and observed inundation area during the extreme historical flood events. A simple scheme was carried out to consider the impacts of flood control measures, including the reservoirs in the headwaters and the dykes to be built. By comparing model simulations with and without the influences of flood control measures, we demonstrated the importance of human influences in altering the inundated area and depth under design flood conditions. Based on the SRTM DEM and dam and reservoir data in the Global Reservoir and Dam (GRanD) database, we further discuss the potential to develop a global flood model with human influences.

Training for Employment: Social Inclusion, Productivity, and Youth Employment. Human Resources Training and Development: Vocational Guidance and Vocational Training. Report V. International Labour Conference (88th Session, 2000). Fifth Item on the Agenda.

ERIC Educational Resources Information Center

International Labour Office, Geneva (Switzerland).

This report examines the human resources development and training dimensions of the gradual, but inexorable, shift towards knowledge-, skill-, and service-based economies and societies, and the stupendous growth of the information and communications technology sectors. Its four chapters explore the following: (1) globalization, technological…

Future Challenges in Managing Human Health and Performance Risks for Space Flight

NASA Technical Reports Server (NTRS)

Corbin, Barbara J.; Barratt, Michael

2013-01-01

The global economy forces many nations to consider their national investments and make difficult decisions regarding their investment in future exploration. To enable safe, reliable, and productive human space exploration, we must pool global resources to understand and mitigate human health & performance risks prior to embarking on human exploration of deep space destinations. Consensus on the largest risks to humans during exploration is required to develop an integrated approach to mitigating risks. International collaboration in human space flight research will focus research on characterizing the effects of spaceflight on humans and the development of countermeasures or systems. Sharing existing data internationally will facilitate high quality research and sufficient power to make sound recommendations. Efficient utilization of ISS and unique ground-based analog facilities allows greater progress. Finally, a means to share results of human research in time to influence decisions for follow-on research, system design, new countermeasures and medical practices should be developed. Although formidable barriers to overcome, International working groups are working to define the risks, establish international research opportunities, share data among partners, share flight hardware and unique analog facilities, and establish forums for timely exchange of results. Representatives from the ISS partnership research and medical communities developed a list of the top ten human health & performance risks and their impact on exploration missions. They also drafted a multilateral data sharing plan to establish guidelines and principles for sharing human spaceflight data. Other working groups are also developing methods to promote international research solicitations. Collaborative use of analog facilities and shared development of space flight research and medical hardware continues. Establishing a forum for exchange of results between researchers, aerospace physicians and program managers takes careful consideration of researcher concerns and decision maker needs. Active participation by researchers in the development of this forum is essential, and the benefit can be tremendous. The ability to rapidly respond to research results without compromising publication rights and intellectual property will facilitate timely reduction in human health and performance risks in support of international exploration missions.

Antimicrobial resistance: A global emerging threat to public health systems.

PubMed

Ferri, Maurizio; Ranucci, Elena; Romagnoli, Paola; Giaccone, Valerio

2017-09-02

Antimicrobial resistance (AMR) became in the last two decades a global threat to public health systems in the world. Since the antibiotic era, with the discovery of the first antibiotics that provided consistent health benefits to human medicine, the misuse and abuse of antimicrobials in veterinary and human medicine have accelerated the growing worldwide phenomenon of AMR. This article presents an extensive overview of the epidemiology of AMR, with a focus on the link between food producing-animals and humans and on the legal framework and policies currently implemented at the EU level and globally. The ways of responding to the AMR challenges foresee an array of measures that include: designing more effective preventive measures at farm level to reduce the use of antimicrobials; development of novel antimicrobials; strengthening of AMR surveillance system in animal and human populations; better knowledge of the ecology of resistant bacteria and resistant genes; increased awareness of stakeholders on the prudent use of antibiotics in animal productions and clinical arena; and the public health and environmental consequences of AMR. Based on the global nature of AMR and considering that bacterial resistance does not recognize barriers and can spread to people and the environment, the article ends with specific recommendations structured around a holistic approach and targeted to different stakeholders.

Development of new impact functions for global risk caused by climate change

NASA Astrophysics Data System (ADS)

Miyazaki, C.

2014-12-01

The purpose of our study is to identify and quantify global-scale risks which can be caused by future climate change. In particular, we focus on the global-scale risks which have critical impacts to human environments. Use of impact functions is one of the common way to quantify global-scale risks. Output of impact function is climate impacts (e.g. economic damage by temperature increasing) and input can be global temperature increasing and/or socioeconomic condition (e.g. GDP). As the first step of study, we referred to AR5 WG II report (AR5, hereafter) and comprehensive inventories of climate change risks developed by Strategic R&D Area Project of the Environment Research and Technology Development Fund (ICA-RUS project). Then we extracted information which can be used to develop impact function from them. By following SPM/AR5, we focused on 11 sectors and extracted quantitative description on climate impacts from the AR5 and paper/reports cited in AR5. As a result, we identified about 40 risk items to focus as global-scale risks by climate change. Using the collected information, we tentatively made impact function on sea level rise and so on. In addition, we also extracted the impact functions used in Integrated Assessment Models (IAMs). The literature survey on IAM suggested the risk items considered in IAMs are limited. For instance, although FUND model provides detailed impact functions compared with most of other IAMs, its impact functions deal with only several sectors (e.g. agriculture, forestry, biodiversity, sea level rise, human health, energy demand and water resources). The survey on impact functions in IAMs also suggested impact function for abrupt climate change (so-called Tipping Element) is premature. Moreover, as example for quantifying health risk by our calculation, we also present the result on global-scale projection of the health burden attributable to childhood undernutrition (Ishida et al., 2014, ERL).

Comparison of human embryomorphokinetic parameters in sequential or global culture media.

PubMed

Kazdar, Nadia; Brugnon, Florence; Bouche, Cyril; Jouve, Guilhem; Veau, Ségolène; Drapier, Hortense; Rousseau, Chloé; Pimentel, Céline; Viard, Patricia; Belaud-Rotureau, Marc-Antoine; Ravel, Célia

2017-08-01

A prospective study on randomized patients was conducted to determine how morphokinetic parameters are altered in embryos grown in sequential versus global culture media. Eleven morphokinetic parameters of 160 single embryos transferred were analyzed by time lapse imaging involving two University-affiliated in vitro fertilization (IVF) centers. We found that the fading of the two pronuclei occurred earlier in global (22.56±2.15 hpi) versus sequential media (23.63±2.71 hpi; p=0.0297). Likewise, the first cleavage started earlier at 24.52±2.33 hpi vs 25.76±2.95 hpi (p=0.0158). Also, the first cytokinesis was shorter in global medium, lasting 18±10.2 minutes in global versus 36±37.8 minutes in sequential culture medium (p <0.0001). We also observed a significant shortening in the duration of the 2-cell stage in sequential medium: 10.64 h±2.75 versus 11.66 h±1.11 in global medium (p=0.0225) which suggested a faster progression of the embryos through their first mitotic cell cycle. In conclusion, morphokinetic analysis of human embryos by Time lapse imaging reveals significant differences in five kinetic variables according to culture medium. Our study highlights the need to adapt morphokinetic analysis accordingly to the type of media used to best support human early embryo development.

Global mapping of Al, Cu, Fe, and Zn in-use stocks and in-ground resources

PubMed Central

Rauch, Jason N.

2009-01-01

Human activity has become a significant geomorphic force in modern times, resulting in unprecedented movements of material around Earth. An essential constituent of this material movement, the major industrial metals aluminium, copper, iron, and zinc in the human-built environment are mapped globally at 1-km nominal resolution for the year 2000 and compared with the locations of present-day in-ground resources. While the maps of in-ground resources generated essentially combine available databases, the mapping methodology of in-use stocks relies on the linear regression between gross domestic product and both in-use stock estimates and the Nighttime Lights of the World dataset. As the first global maps of in-use metal stocks, they reveal that a full 25% of the world's Fe, Al, Cu, and Zn in-use deposits are concentrated in three bands: (i) the Eastern seaboard from Washington, D.C. to Boston in the United States, (ii) England, Benelux into Germany and Northern Italy, and (iii) South Korea and Japan. This pattern is consistent across all metals investigated. In contrast, the global maps of primary metal resources reveal these deposits are more evenly distributed between the developed and developing worlds, with the distribution pattern differing depending on the metal. This analysis highlights the magnitude at which in-ground metal resources have been translocated to in-use stocks, largely from highly concentrated but globally dispersed in-ground deposits to more diffuse in-use stocks located primarily in developed urban regions. PMID:19858486

A human-driven decline in global burned area

NASA Astrophysics Data System (ADS)

Andela, N.

2017-12-01

Fire regimes are changing rapidly across the globe, driven by human land management and climate. We assessed long-term trends in fire activity using multiple satellite data sets and developed a new global data set on individual fire dynamics to understand the implications of changing fire regimes. Despite warming climate, burned area declined across most of the tropics, contributing to a global decline in burned area of 24.3 ± 8.8% over the past 18 years. The estimated decrease in burned area was largest in savannas and grasslands, where agricultural expansion and intensification were primary drivers of declining fire activity. In tropical forests, frequent fires for deforestation and agricultural management yield a sharp rise in fire activity with the expansion of settled land uses, but the use of fire decreases with increasing investment in agricultural areas in both savanna and forested landscapes. Disparate patterns of recent socieconomic development resulted in contrasting fire trends between southern Africa (increase) and South America (decrease). A strong inverse relationship between burned area and economic development in savannas and grasslands suggests that despite potential increasing fire risk from climate change, ongoing socioeconomic development will likely sustain observed declines in fire in these ecosystems during coming decades. Fewer and smaller fires reduced aerosol concentrations, modified vegetation structure, and increased the magnitude of the terrestrial carbon sink. The spatiotemporal distribution of fire size, duration, speed and direction of spread provided new insights in continental scale differences in fire regimes driven by human and climatic factors. Understanding these dynamics over larger scales is critical to achieve a balance between conservation of fire-dependent ecosystems and increasing agricultural production to support growing populations that will require careful management of fire activity in human-dominated landscapes.

Vaccines to combat the neglected tropical diseases.

PubMed

Bethony, Jeffrey M; Cole, Rhea N; Guo, Xiaoti; Kamhawi, Shaden; Lightowlers, Marshall W; Loukas, Alex; Petri, William; Reed, Steven; Valenzuela, Jesus G; Hotez, Peter J

2011-01-01

The neglected tropical diseases (NTDs) represent a group of parasitic and related infectious diseases such as amebiasis, Chagas disease, cysticercosis, echinococcosis, hookworm, leishmaniasis, and schistosomiasis. Together, these conditions are considered the most common infections in low- and middle-income countries, where they produce a level of global disability and human suffering equivalent to better known conditions such as human immunodeficiency virus/acquired immunodeficiency syndrome and malaria. Despite their global public health importance, progress on developing vaccines for NTD pathogens has lagged because of some key technical hurdles and the fact that these infections occur almost exclusively in the world's poorest people living below the World Bank poverty line. In the absence of financial incentives for new products, the multinational pharmaceutical companies have not embarked on substantive research and development programs for the neglected tropical disease vaccines. Here, we review the current status of scientific and technical progress in the development of new neglected tropical disease vaccines, highlighting the successes that have been achieved (cysticercosis and echinococcosis) and identifying the challenges and opportunities for development of new vaccines for NTDs. Also highlighted are the contributions being made by non-profit product development partnerships that are working to overcome some of the economic challenges in vaccine manufacture, clinical testing, and global access. © 2010 John Wiley & Sons A/S.

Vaccines to combat the neglected tropical diseases

PubMed Central

Bethony, Jeffrey M.; Cole, Rhea N.; Guo, Xiaoti; Kamhawi, Shaden; Lightowlers, Marshall W.; Loukas, Alex; Petri, William; Reed, Steven; Valenzuela, Jesus G.; Hotez, Peter J.

2012-01-01

Summary The neglected tropical diseases (NTDs) represent a group of parasitic and related infectious diseases such as amebiasis, Chagas disease, cysticercosis, echinococcosis, hookworm, leishmaniasis, and schistosomiasis. Together, these conditions are considered the most common infections in low- and middle-income countries, where they produce a level of global disability and human suffering equivalent to better known conditions such as human immunodeficiency virus/acquired immunodeficiency syndrome and malaria. Despite their global public health importance, progress on developing vaccines for NTD pathogens has lagged because of some key technical hurdles and the fact that these infections occur almost exclusively in the world’s poorest people living below the World Bank poverty line. In the absence of financial incentives for new products, the multinational pharmaceutical companies have not embarked on substantive research and development programs for the neglected tropical disease vaccines. Here, we review the current status of scientific and technical progress in the development of new neglected tropical disease vaccines, highlighting the successes that have been achieved (cysticercosis and echinococcosis) and identifying the challenges and opportunities for development of new vaccines for NTDs. Also highlighted are the contributions being made by non-profit product development partnerships that are working to overcome some of the economic challenges in vaccine manufacture, clinical testing, and global access. PMID:21198676

[Globalization and infectious diseases].

PubMed

Mirski, Tomasz; Bartoszcze, Michał; Bielawska-Drózd, Agata

2011-01-01

Globalization is a phenomenon characteristic of present times. It can be considered in various aspects: economic, environmental changes, demographic changes, as well as the development of new technologies. All these aspects of globalization have a definite influence on the emergence and spread of infectious diseases. Economic aspects ofglobalization are mainly the trade development, including food trade, which has an impact on the spread of food-borne diseases. The environmental changes caused by intensive development of industry, as a result of globalization, which in turn affects human health. The demographic changes are mainly people migration between countries and rural and urban areas, which essentially favors the global spread of many infectious diseases. While technological advances prevents the spread of infections, for example through better access to information, it may also increase the risk, for example through to create opportunities to travel into more world regions, including the endemic regions for various diseases. The phenomenon ofglobalization is also closely associated with the threat of terrorism, including bioterrorism. It forces the governments of many countries to develop effective programs to protect and fight against this threat.

Global human capital: integrating education and population.

PubMed

Lutz, Wolfgang; KC, Samir

2011-07-29

Almost universally, women with higher levels of education have fewer children. Better education is associated with lower mortality, better health, and different migration patterns. Hence, the global population outlook depends greatly on further progress in education, particularly of young women. By 2050, the highest and lowest education scenarios--assuming identical education-specific fertility rates--result in world population sizes of 8.9 and 10.0 billion, respectively. Better education also matters for human development, including health, economic growth, and democracy. Existing methods of multi-state demography can quantitatively integrate education into standard demographic analysis, thus adding the "quality" dimension.

Nanotechnology in global medicine and human biosecurity: private interests, policy dilemmas, and the calibration of public health law.

PubMed

Faunce, Thomas A

2007-01-01

This paper considers how best to approach dilemmas posed to global health and biosecurity policy by increasing advances in practical applications of nanotechnology. The type of nano-technology policy dilemmas discussed include: (1) expenditure of public funds, (2) public-funded research priorities, (3) public confidence in government and science and, finally, (4) public safety. The article examines the value in this context of a legal obligation that the development of relevant public health law be calibrated against less corporate-influenced norms issuing from bioethics and international human rights.

Fuzzy Integral-Based Gaze Control of a Robotic Head for Human Robot Interaction.

PubMed

Yoo, Bum-Soo; Kim, Jong-Hwan

2015-09-01

During the last few decades, as a part of effort to enhance natural human robot interaction (HRI), considerable research has been carried out to develop human-like gaze control. However, most studies did not consider hardware implementation, real-time processing, and the real environment, factors that should be taken into account to achieve natural HRI. This paper proposes a fuzzy integral-based gaze control algorithm, operating in real-time and the real environment, for a robotic head. We formulate the gaze control as a multicriteria decision making problem and devise seven human gaze-inspired criteria. Partial evaluations of all candidate gaze directions are carried out with respect to the seven criteria defined from perceived visual, auditory, and internal inputs, and fuzzy measures are assigned to a power set of the criteria to reflect the user defined preference. A fuzzy integral of the partial evaluations with respect to the fuzzy measures is employed to make global evaluations of all candidate gaze directions. The global evaluation values are adjusted by applying inhibition of return and are compared with the global evaluation values of the previous gaze directions to decide the final gaze direction. The effectiveness of the proposed algorithm is demonstrated with a robotic head, developed in the Robot Intelligence Technology Laboratory at Korea Advanced Institute of Science and Technology, through three interaction scenarios and three comparison scenarios with another algorithm.

Human Driving Forces and Their Impacts on Land Use/Land Cover. Hands-On! Developing Active Learning Modules on the Human Dimensions of Global Change.

ERIC Educational Resources Information Center

Moser, Susanne

This learning module aims to engage students in problem solving, critical thinking, scientific inquiry, and cooperative learning. The module is appropriate for use in any introductory or intermediate undergraduate course that focuses on human-environment relationships. The module explains that land use/cover change has occurred at all times in all…

Sustainability, collapse and oscillations in a simple World-Earth model

NASA Astrophysics Data System (ADS)

Nitzbon, Jan; Heitzig, Jobst; Parlitz, Ulrich

2017-07-01

The Anthropocene is characterized by close interdependencies between the natural Earth system and the global human society, posing novel challenges to model development. Here we present a conceptual model describing the long-term co-evolution of natural and socio-economic subsystems of Earth. While the climate is represented via a global carbon cycle, we use economic concepts to model socio-metabolic flows of biomass and fossil fuels between nature and society. A well-being-dependent parametrization of fertility and mortality governs human population dynamics. Our analysis focuses on assessing possible asymptotic states of the Earth system for a qualitative understanding of its complex dynamics rather than quantitative predictions. Low dimension and simple equations enable a parameter-space analysis allowing us to identify preconditions of several asymptotic states and hence fates of humanity and planet. These include a sustainable co-evolution of nature and society, a global collapse and everlasting oscillations. We consider different scenarios corresponding to different socio-cultural stages of human history. The necessity of accounting for the ‘human factor’ in Earth system models is highlighted by the finding that carbon stocks during the past centuries evolved opposing to what would ‘naturally’ be expected on a planet without humans. The intensity of biomass use and the contribution of ecosystem services to human well-being are found to be crucial determinants of the asymptotic state in a (pre-industrial) biomass-only scenario without capital accumulation. The capitalistic, fossil-based scenario reveals that trajectories with fundamentally different asymptotic states might still be almost indistinguishable during even a centuries-long transient phase. Given current human population levels, our study also supports the claim that besides reducing the global demand for energy, only the extensive use of renewable energies may pave the way into a sustainable future.

The Impact of Skills Development on Competitiveness: Empirical Evidence from a Cross-Country Analysis

ERIC Educational Resources Information Center

Onsomu, Eldah N.; Ngware, Moses W.; Manda, Damiano K.

2010-01-01

In the past half-century, most countries have emphasized the development of human capital as an instrument for economic growth, sustainable development, and improved global competitiveness. However, limited evidence exists on the link between skills development and a country's competitiveness. This paper examines the contribution and association…

Citizen-science, Geoethics and Human Niche

NASA Astrophysics Data System (ADS)

Bohle, Martin

2017-04-01

The anthropogenic biogeosphere or 'human niche' is the intersection of the biogeosphere and the sphere of human activities of social, economic, cultural and political nature. The application case for geoethics, namely "appropriate behaviours and practices, wherever human activities interact with the Earth system" [1], is about niche building. Geoethics is about the conduct of people and geoscientists, respectively their ordinary lifestyles and professional activities. Geoscience professionals notice the diverse economic, social and cultural living conditions of people, and the application cases of geosciences mirror the diversity of the global social sphere. Subsequently it is argued: A) when considering the ethical dimensions of global niche building then geosciences should feature 'citizen geoscience'; and B) when considering the functioning of a knowledge-based society under conditions of anthropogenic global change then 'citizen geoscience' facilitates applying that knowledge base. (A) Regarding 'niche building': The design of production systems and consumption patterns embeds geoscience know-how and relates it to the everyday life. Any citizen's activities purposefully interconnect to the biogeosphere for well-being, care-taking, and reproduction, although habitually without involving a geoscientist in professional capacity. In that implicit manner the everyday behaviours and practices of people influence Earth system dynamic. This renders their inherent geoscience know-how a public good as it makes their ignorance a public risk. A comfortable human niche for billions of people requires a global biogeosphere that is disrupted little by citizens' activities and exposes them to hazards that can be tamed. Quite the reverse, anthropogenic global change will disturb living conditions for many citizen. Much geoscience know-how will have to be deployed to tame disturbances in a socially sustainable manner. Sustainability in turn needs involvement of citizens in researching know-how and deploying it, i.e. needs 'citizen geo-scientists' to maintain the human niche. (B) Regarding knowledge-based societies: The rapidly increasing human knowledge base accelerates the scientific-technical revolution. Its industrial-societal implementation confronts societies with numerous change processes. Their speed and scope is a risk as well as the mutual interferences of different change processes that often only get obvious within everyday societal doings. This vigour of change requires robust two-way linkages between research and technological development on one side and societal activities on the other side. Research and development undertaken in cooperation with citizen scientists would improve such linkages, e.g. through increased transparency of research and development or strengthening the sense of belonging of people for their environments. Citizen scientists are a resource, because they are complementary partner to the professional researcher. On one side citizen scientists provide experiences that are rooted in everyday practices and on the other side they facilitate uptake of new practices. Both features are needed in societies that face anthropogenic global change. Summarizing, geoethics affiliates geosciences and 'citizen science' in a particular relationship, i.e. 'citizen geo-science', which is beneficial for knowledge-based societies that are functioning under conditions of anthropogenic global change. [1] http://www.geoethics.org/ (accessed: 8th November 2016) Disclaimer: The views expressed engage the author only, not the employer.

Global terrestrial Human Footprint maps for 1993 and 2009

PubMed Central

Venter, Oscar; Sanderson, Eric W.; Magrach, Ainhoa; Allan, James R.; Beher, Jutta; Jones, Kendall R.; Possingham, Hugh P.; Laurance, William F.; Wood, Peter; Fekete, Balázs M.; Levy, Marc A.; Watson, James E.M.

2016-01-01

Remotely-sensed and bottom-up survey information were compiled on eight variables measuring the direct and indirect human pressures on the environment globally in 1993 and 2009. This represents not only the most current information of its type, but also the first temporally-consistent set of Human Footprint maps. Data on human pressures were acquired or developed for: 1) built environments, 2) population density, 3) electric infrastructure, 4) crop lands, 5) pasture lands, 6) roads, 7) railways, and 8) navigable waterways. Pressures were then overlaid to create the standardized Human Footprint maps for all non-Antarctic land areas. A validation analysis using scored pressures from 3114×1 km2 random sample plots revealed strong agreement with the Human Footprint maps. We anticipate that the Human Footprint maps will find a range of uses as proxies for human disturbance of natural systems. The updated maps should provide an increased understanding of the human pressures that drive macro-ecological patterns, as well as for tracking environmental change and informing conservation science and application. PMID:27552448

International obligations through collective rights: Moving from foreign health assistance to global health governance.

PubMed

Meier, Benjamin Mason; Fox, Ashley M

2010-06-15

This article analyzes the growing chasm between international power and state responsibility in health rights, proposing an international legal framework for collective rights - rights that can reform international institutions and empower developing states to realize the determinants of health structured by global forces. With longstanding recognition that many developing state governments cannot realize the health of their peoples without international cooperation, scholars have increasingly sought to codify international obligations under the purview of an evolving human right to health, applying this rights-based approach as a foundational framework for reducing global health inequalities through foreign assistance. Yet the inherent limitations of the individual human rights framework stymie the right to health in impacting the global institutions that are most crucial for realizing underlying determinants of health through the strengthening of primary health care systems. Whereas the right to health has been advanced as an individual right to be realized by a state duty-bearer, the authors find that this limited, atomized right has proven insufficient to create accountability for international obligations in global health policy, enabling the deterioration of primary health care systems that lack the ability to address an expanding set of public health claims. For rights scholars to advance disease protection and health promotion through national primary health care systems - creating the international legal obligations necessary to spur development supportive of the public's health - the authors conclude that scholars must look beyond the individual right to health to create collective international legal obligations commensurate with a public health-centered approach to primary health care. Through the development and implementation of these collective health rights, states can address interconnected determinants of health within and across countries, obligating the international community to scale-up primary health care systems in the developing world and thereby reduce public health inequities through global health governance.

SUSTAINABILITY. Comment on "Planetary boundaries: Guiding human development on a changing planet".

PubMed

Jaramillo, Fernando; Destouni, Georgia

2015-06-12

Steffen et al. (Research Articles, 13 February 2015, p. 736) recently assessed current global freshwater use, finding it to be well below a corresponding planetary boundary. However, they ignored recent scientific advances implying that the global consumptive use of freshwater may have already crossed the associated planetary boundary. Copyright © 2015, American Association for the Advancement of Science.

A human development framework for CO2 reductions.

PubMed

Costa, Luís; Rybski, Diego; Kropp, Jürgen P

2011-01-01

Although developing countries are called to participate in CO(2) emission reduction efforts to avoid dangerous climate change, the implications of proposed reduction schemes in human development standards of developing countries remain a matter of debate. We show the existence of a positive and time-dependent correlation between the Human Development Index (HDI) and per capita CO(2) emissions from fossil fuel combustion. Employing this empirical relation, extrapolating the HDI, and using three population scenarios, the cumulative CO(2) emissions necessary for developing countries to achieve particular HDI thresholds are assessed following a Development As Usual approach (DAU). If current demographic and development trends are maintained, we estimate that by 2050 around 85% of the world's population will live in countries with high HDI (above 0.8). In particular, 300 Gt of cumulative CO(2) emissions between 2000 and 2050 are estimated to be necessary for the development of 104 developing countries in the year 2000. This value represents between 20 % to 30 % of previously calculated CO(2) budgets limiting global warming to 2 °C. These constraints and results are incorporated into a CO(2) reduction framework involving four domains of climate action for individual countries. The framework reserves a fair emission path for developing countries to proceed with their development by indexing country-dependent reduction rates proportional to the HDI in order to preserve the 2 °C target after a particular development threshold is reached. For example, in each time step of five years, countries with an HDI of 0.85 would need to reduce their per capita emissions by approx. 17% and countries with an HDI of 0.9 by 33 %. Under this approach, global cumulative emissions by 2050 are estimated to range from 850 up to 1100 Gt of CO(2). These values are within the uncertainty range of emissions to limit global temperatures to 2 °C. © 2011 Costa et al.

A Human Development Framework for CO2 Reductions

PubMed Central

Costa, Luís; Rybski, Diego; Kropp, Jürgen P.

2011-01-01

Although developing countries are called to participate in CO2 emission reduction efforts to avoid dangerous climate change, the implications of proposed reduction schemes in human development standards of developing countries remain a matter of debate. We show the existence of a positive and time-dependent correlation between the Human Development Index (HDI) and per capita CO2 emissions from fossil fuel combustion. Employing this empirical relation, extrapolating the HDI, and using three population scenarios, the cumulative CO2 emissions necessary for developing countries to achieve particular HDI thresholds are assessed following a Development As Usual approach (DAU). If current demographic and development trends are maintained, we estimate that by 2050 around 85% of the world’s population will live in countries with high HDI (above 0.8). In particular, 300 Gt of cumulative CO2 emissions between 2000 and 2050 are estimated to be necessary for the development of 104 developing countries in the year 2000. This value represents between 20 % to 30 % of previously calculated CO2 budgets limiting global warming to 2°C. These constraints and results are incorporated into a CO2 reduction framework involving four domains of climate action for individual countries. The framework reserves a fair emission path for developing countries to proceed with their development by indexing country-dependent reduction rates proportional to the HDI in order to preserve the 2°C target after a particular development threshold is reached. For example, in each time step of five years, countries with an HDI of 0.85 would need to reduce their per capita emissions by approx. 17% and countries with an HDI of 0.9 by 33 %. Under this approach, global cumulative emissions by 2050 are estimated to range from 850 up to 1100 Gt of CO2. These values are within the uncertainty range of emissions to limit global temperatures to 2°C. PMID:22216227

A survey of Applied Psychological Services' models of the human operator

NASA Technical Reports Server (NTRS)

Siegel, A. I.; Wolf, J. J.

1979-01-01

A historical perspective is presented in terms of the major features and status of two families of computer simulation models in which the human operator plays the primary role. Both task oriented and message oriented models are included. Two other recent efforts are summarized which deal with visual information processing. They involve not whole model development but a family of subroutines customized to add the human aspects to existing models. A global diagram of the generalized model development/validation process is presented and related to 15 criteria for model evaluation.

Towards a viable and just global nursing ethics.

PubMed

Crigger, Nancy J

2008-01-01

Globalization, an outgrowth of technology, while informing us about people throughout the world, also raises our awareness of the extreme economic and social disparities that exist among nations. As part of a global discipline, nurses are vitally interested in reducing and eliminating disparities so that better health is achieved for all people. Recent literature in nursing encourages our discipline to engage more actively with social justice issues. Justice in health care is a major commitment of nursing; thus questions in the larger sphere of globalization, justice and ethics, are our discipline's questions also. Global justice, or fairness, is not an issue for some groups or institutions, but a deeper human rights issue that is a responsibility for everyone. What can we do to help reduce or eliminate the social and economic disparities that are so evident? What kind of ethical milieu is needed to address the threat that globalization imposes on justice and fairness? This article enriches the conceptualization of globalization by investigating recent work by Schweiker and Twiss. In addition, I discuss five qualities or characteristics that will facilitate the development of a viable and just global ethic. A global ethic guides all people in their response to human rights and poverty. Technology and business, two major forces in globalization that are generally considered beneficial, are critiqued as barriers to social justice and the common good.

Theodore E. Woodward Award: Global Warming and the Human Stomach: Microecology Follows Macroecology

PubMed Central

Blaser, Martin J

2005-01-01

Just as there have been 20th century changes in our “macroecology,” including global warming, there have been alterations in our “microecology,” involving the microbial populations that colonize the human body. Helicobacter pylori, an ancient inhabitant of the human stomach, has been disappearing over the course of the 20th century. As such, by comparing H. pylori+ and H. pylori− persons, the consequences of its colonization can be determined. The presence of H. pylori is associated with increased risk for development of gastric cancer and peptic ulceration, and with decreased risk for gastroesophageal reflux disease (GERD) and its sequelae, including esophageal adenocarcinoma. The disappearance of H. pylori (especially cag+ strains), possibly contributing to the risk of these esophageal diseases, may be an indicator for changing human microecology. PMID:16555606

Public Health Crisis in War and Conflict - Health Security in Aggregate.

PubMed

Quinn, John; Zelený, Tomáš; Subramaniam, Rammika; Bencko, Vladimír

2017-03-01

Public health status of populations is multifactorial and besides other factors it is linked to war and conflict. Public health crisis can erupt when states go to war or are invaded; health security may be reduced for affected populations. This study reviews in aggregate multiple indices of human security, human development and legitimacy of the state in order to describe a predictable global health portrait. Paradigm shift of large global powers to that non-state actors and proxies impact regional influence through scaled conflict and present major global health challenges for policy makers. Small scale conflict with large scale violence threatens health security for at-risk populations. The paper concludes that health security is directly proportional to state security. Copyright© by the National Institute of Public Health, Prague 2017

Women's labour and economic globalisation: a participatory workshop created by Alternative Women in Development (Alt-WID).

PubMed

Barton, C; Nazombei, E

2000-03-01

This article describes the aims, methods, materials and topics used in a participatory workshop created by Alternative Women in Development. The organization aims to bridge the gaps in analyzing human rights and economic justice in both North and South from a feminist perspective through a workshop. This workshop considers the varied roles that women play in the global economy and features a series of anecdotes to illustrate the diverse ways in which globalization affects women in all regions worldwide. The workshop runs for a minimum of 3 hours and is structured as follows: introduction; plenary: identifying the human rights of the women; small-group work, plenary: building a group analysis and discussion of alternatives to the existing policies; and individual and plenary evaluations. Furthermore, four anecdotes used at the workshop are presented. Among the outcomes of the workshop included the identification of the problem causes and development of strategies for action.

Global tropospheric chemistry: A plan for action

NASA Technical Reports Server (NTRS)

1984-01-01

Prompted by an increasing awareness of the influence of human activity on the chemistry of the global troposphere, a panel was formed to (1) assess the requirement for a global study of the chemistry of the troposphere; (2) develop a scientific strategy for a comprehensive plan taking into account the existing and projected programs of the government; (3) assess the requirements of a global study in terms of theoretical knowledge, numerical modeling, instrumentation, observing platforms, ground-level observational techniques, and other related needs; and (4) outline the appropriate sequence and coordination required to achieve the most effective utilization of available resources. Part 1 presents a coordinated national blueprint for scientific investigations of biogeochemical cycles in the global troposphere. part 2 presents much of the background information of the present knowledge and gaps in the understanding of tropospheric chemical cycles and processes from which the proposed program was developed.

Global tropospheric chemistry: A plan for action

NASA Astrophysics Data System (ADS)

1984-10-01

Prompted by an increasing awareness of the influence of human activity on the chemistry of the global troposphere, a panel was formed to (1) assess the requirement for a global study of the chemistry of the troposphere; (2) develop a scientific strategy for a comprehensive plan taking into account the existing and projected programs of the government; (3) assess the requirements of a global study in terms of theoretical knowledge, numerical modeling, instrumentation, observing platforms, ground-level observational techniques, and other related needs; and (4) outline the appropriate sequence and coordination required to achieve the most effective utilization of available resources. Part 1 presents a coordinated national blueprint for scientific investigations of biogeochemical cycles in the global troposphere. part 2 presents much of the background information of the present knowledge and gaps in the understanding of tropospheric chemical cycles and processes from which the proposed program was developed.

The human dimension of fire regimes on Earth.

PubMed

Bowman, David M J S; Balch, Jennifer; Artaxo, Paulo; Bond, William J; Cochrane, Mark A; D'Antonio, Carla M; Defries, Ruth; Johnston, Fay H; Keeley, Jon E; Krawchuk, Meg A; Kull, Christian A; Mack, Michelle; Moritz, Max A; Pyne, Stephen; Roos, Christopher I; Scott, Andrew C; Sodhi, Navjot S; Swetnam, Thomas W; Whittaker, Robert

2011-12-01

Humans and their ancestors are unique in being a fire-making species, but 'natural' (i.e. independent of humans) fires have an ancient, geological history on Earth. Natural fires have influenced biological evolution and global biogeochemical cycles, making fire integral to the functioning of some biomes. Globally, debate rages about the impact on ecosystems of prehistoric human-set fires, with views ranging from catastrophic to negligible. Understanding of the diversity of human fire regimes on Earth in the past, present and future remains rudimentary. It remains uncertain how humans have caused a departure from 'natural' background levels that vary with climate change. Available evidence shows that modern humans can increase or decrease background levels of natural fire activity by clearing forests, promoting grazing, dispersing plants, altering ignition patterns and actively suppressing fires, thereby causing substantial ecosystem changes and loss of biodiversity. Some of these contemporary fire regimes cause substantial economic disruptions owing to the destruction of infrastructure, degradation of ecosystem services, loss of life, and smoke-related health effects. These episodic disasters help frame negative public attitudes towards landscape fires, despite the need for burning to sustain some ecosystems. Greenhouse gas-induced warming and changes in the hydrological cycle may increase the occurrence of large, severe fires, with potentially significant feedbacks to the Earth system. Improved understanding of human fire regimes demands: (1) better data on past and current human influences on fire regimes to enable global comparative analyses, (2) a greater understanding of different cultural traditions of landscape burning and their positive and negative social, economic and ecological effects, and (3) more realistic representations of anthropogenic fire in global vegetation and climate change models. We provide an historical framework to promote understanding of the development and diversification of fire regimes, covering the pre-human period, human domestication of fire, and the subsequent transition from subsistence agriculture to industrial economies. All of these phases still occur on Earth, providing opportunities for comparative research.

The human dimension of fire regimes on Earth

PubMed Central

Bowman, David M J S; Balch, Jennifer; Artaxo, Paulo; Bond, William J; Cochrane, Mark A; D'Antonio, Carla M; DeFries, Ruth; Johnston, Fay H; Keeley, Jon E; Krawchuk, Meg A; Kull, Christian A; Mack, Michelle; Moritz, Max A; Pyne, Stephen; Roos, Christopher I; Scott, Andrew C; Sodhi, Navjot S; Swetnam, Thomas W; Whittaker, Robert

2011-01-01

Humans and their ancestors are unique in being a fire-making species, but ‘natural’ (i.e. independent of humans) fires have an ancient, geological history on Earth. Natural fires have influenced biological evolution and global biogeochemical cycles, making fire integral to the functioning of some biomes. Globally, debate rages about the impact on ecosystems of prehistoric human-set fires, with views ranging from catastrophic to negligible. Understanding of the diversity of human fire regimes on Earth in the past, present and future remains rudimentary. It remains uncertain how humans have caused a departure from ‘natural’ background levels that vary with climate change. Available evidence shows that modern humans can increase or decrease background levels of natural fire activity by clearing forests, promoting grazing, dispersing plants, altering ignition patterns and actively suppressing fires, thereby causing substantial ecosystem changes and loss of biodiversity. Some of these contemporary fire regimes cause substantial economic disruptions owing to the destruction of infrastructure, degradation of ecosystem services, loss of life, and smoke-related health effects. These episodic disasters help frame negative public attitudes towards landscape fires, despite the need for burning to sustain some ecosystems. Greenhouse gas-induced warming and changes in the hydrological cycle may increase the occurrence of large, severe fires, with potentially significant feedbacks to the Earth system. Improved understanding of human fire regimes demands: (1) better data on past and current human influences on fire regimes to enable global comparative analyses, (2) a greater understanding of different cultural traditions of landscape burning and their positive and negative social, economic and ecological effects, and (3) more realistic representations of anthropogenic fire in global vegetation and climate change models. We provide an historical framework to promote understanding of the development and diversification of fire regimes, covering the pre-human period, human domestication of fire, and the subsequent transition from subsistence agriculture to industrial economies. All of these phases still occur on Earth, providing opportunities for comparative research. PMID:22279247

The human dimension of fire regimes on Earth

USGS Publications Warehouse

Bowman, David M.J.S.; Balch, Jennifer; Artaxo, Paulo; Bond, William J.; Cochrane, Mark A.; D'Antonio, Carla M.; DeFries, Ruth; Johnston, Fay H.; Keeley, Jon E.; Krawchuk, Meg A.; Kull, Christian A.; Michelle, Mack; Moritz, Max A.; Pyne, Stephen; Roos, Christopher I.; Scott, Andrew C.; Sodhi, Navjot S.; Swetnam, Thomas W.

2011-01-01

Humans and their ancestors are unique in being a fire-making species, but 'natural' (i.e. independent of humans) fires have an ancient, geological history on Earth. Natural fires have influenced biological evolution and global biogeochemical cycles, making fire integral to the functioning of some biomes. Globally, debate rages about the impact on ecosystems of prehistoric human-set fires, with views ranging from catastrophic to negligible. Understanding of the diversity of human fire regimes on Earth in the past, present and future remains rudimentary. It remains uncertain how humans have caused a departure from 'natural' background levels that vary with climate change. Available evidence shows that modern humans can increase or decrease background levels of natural fire activity by clearing forests, promoting grazing, dispersing plants, altering ignition patterns and actively suppressing fires, thereby causing substantial ecosystem changes and loss of biodiversity. Some of these contemporary fire regimes cause substantial economic disruptions owing to the destruction of infrastructure, degradation of ecosystem services, loss of life, and smoke-related health effects. These episodic disasters help frame negative public attitudes towards landscape fires, despite the need for burning to sustain some ecosystems. Greenhouse gas-induced warming and changes in the hydrological cycle may increase the occurrence of large, severe fires, with potentially significant feedbacks to the Earth system. Improved understanding of human fire regimes demands: (1) better data on past and current human influences on fire regimes to enable global comparative analyses, (2) a greater understanding of different cultural traditions of landscape burning and their positive and negative social, economic and ecological effects, and (3) more realistic representations of anthropogenic fire in global vegetation and climate change models. We provide an historical framework to promote understanding of the development and diversification of fire regimes, covering the pre-human period, human domestication of fire, and the subsequent transition from subsistence agriculture to industrial economies. All of these phases still occur on Earth, providing opportunities for comparative research.

Characterization of bovine gamma delta T cells phenotype during post-natal development and following Mycobacterium bovis vaccination or virulent infection

USDA-ARS?s Scientific Manuscript database

Bovine tuberculosis caused by Mycobacterium bovis is a globally significant veterinary health problem. Gamma delta T cells are known to participate in the immune control of mycobacterial infections. Data in human and non-human primates suggest that mycobacterial infection regulates memory/effector p...

Human Stem Cell-Derived Cardiomyocytes: An Alternative Model to Evaluate Environmental Chemical Cardiac Safety and Development of Predictive Adverse Outcome Pathways

EPA Science Inventory

Biomonitoring over the last 14 years has shown human exposure to environmental chemicals has increased ~10-fold (1). In addition, mortality and morbidity related cardiovascular disease continues to be the leading national and global public health issue (2, 3). The association bet...

Adaptive collab orative restoration: a key concept in invasive plant management

Treesearch

James H. Miller; John. Schelhas

2009-01-01

Nonnative invasive species (NNIS) present a severe human dilemma due to their collective threat of replacing and damaging human sustaining ecosystems (U.S. Congress Office of Technology Assessment 1993; Mack et al. 2000; Pimentel 2002). Rapid developments in global trade have caught governments and their regulatory agencies unaware and...

Teaching Global Change in Local Places: The HERO Research Experiences for Undergraduates Program

ERIC Educational Resources Information Center

Yarnal, Brent; Neff, Rob

2007-01-01

The Human-Environment Research Observatory (HERO) Research Experience for Undergraduates (REU) program aimed to develop the next generation of researchers working on place-based human-environment problems. The program followed a cooperative learning model to foster an integrated approach to geographic research and to build collaborative research…

Pathways of human development and carbon emissions embodied in trade

NASA Astrophysics Data System (ADS)

Steinberger, Julia K.; Timmons Roberts, J.; Peters, Glen P.; Baiocchi, Giovanni

2012-02-01

It has long been assumed that human development depends on economic growth, that national economic expansion in turn requires greater energy use and, therefore, increased greenhouse-gas emissions. These interdependences are the topic of current research. Scarcely explored, however, is the impact of international trade: although some nations develop socio-economically and import high-embodied-carbon products, it is likely that carbon-exporting countries gain significantly fewer benefits. Here, we use new consumption-based measures of national carbon emissions to explore how the relationship between human development and carbon changes when we adjust national emission rates for trade. Without such adjustment of emissions, some nations seem to be getting far better development `bang' for the carbon `buck' than others, who are showing scant gains for disproportionate shares of global emissions. Adjusting for the transfer of emissions through trade explains many of these outliers, but shows that further socio-economic benefits are accruing to carbon-importing rather than carbon-exporting countries. We also find that high life expectancies are compatible with low carbon emissions but high incomes are not. Finally, we see that, despite strong international trends, there is no deterministic industrial development trajectory: there is great diversity in pathways, and national histories do not necessarily follow the global trends.

Globalization, democracy, and child health in developing countries.

PubMed

Welander, Anna; Lyttkens, Carl Hampus; Nilsson, Therese

2015-07-01

Good health is crucial for human and economic development. In particular poor health in childhood is of utmost concern since it causes irreversible damage and has implications later in life. Recent research suggests globalization is a strong force affecting adult and child health outcomes. Yet, there is much unexplained variation with respect to the globalization effect on child health, in particular in low- and middle-income countries. One factor that could explain such variation across countries is the quality of democracy. Using panel data for 70 developing countries between 1970 and 2009 this paper disentangles the relationship between globalization, democracy, and child health. Specifically the paper examines how globalization and a country's democratic status and historical experience with democracy, respectively, affect infant mortality. In line with previous research, results suggest that globalization reduces infant mortality and that the level of democracy in a country generally improves child health outcomes. Additionally, democracy matters for the size of the globalization effect on child health. If for example Côte d'Ivoire had been a democracy in the 2000-2009 period, this effect would translate into 1200 fewer infant deaths in an average year compared to the situation without democracy. We also find that nutrition is the most important mediator in the relationship. To conclude, globalization and democracy together associate with better child health in developing countries. Copyright © 2015 Elsevier Ltd. All rights reserved.

The One Health Concept: 10 Years Old and a Long Road Ahead

PubMed Central

Destoumieux-Garzón, Delphine; Mavingui, Patrick; Boetsch, Gilles; Boissier, Jérôme; Darriet, Frédéric; Duboz, Priscilla; Fritsch, Clémentine; Giraudoux, Patrick; Le Roux, Frédérique; Morand, Serge; Paillard, Christine; Pontier, Dominique; Sueur, Cédric; Voituron, Yann

2018-01-01

Over the past decade, a significant increase in the circulation of infectious agents was observed. With the spread and emergence of epizootics, zoonoses, and epidemics, the risks of pandemics became more and more critical. Human and animal health has also been threatened by antimicrobial resistance, environmental pollution, and the development of multifactorial and chronic diseases. This highlighted the increasing globalization of health risks and the importance of the human–animal–ecosystem interface in the evolution and emergence of pathogens. A better knowledge of causes and consequences of certain human activities, lifestyles, and behaviors in ecosystems is crucial for a rigorous interpretation of disease dynamics and to drive public policies. As a global good, health security must be understood on a global scale and from a global and crosscutting perspective, integrating human health, animal health, plant health, ecosystems health, and biodiversity. In this study, we discuss how crucial it is to consider ecological, evolutionary, and environmental sciences in understanding the emergence and re-emergence of infectious diseases and in facing the challenges of antimicrobial resistance. We also discuss the application of the “One Health” concept to non-communicable chronic diseases linked to exposure to multiple stresses, including toxic stress, and new lifestyles. Finally, we draw up a list of barriers that need removing and the ambitions that we must nurture for the effective application of the “One Health” concept. We conclude that the success of this One Health concept now requires breaking down the interdisciplinary barriers that still separate human and veterinary medicine from ecological, evolutionary, and environmental sciences. The development of integrative approaches should be promoted by linking the study of factors underlying stress responses to their consequences on ecosystem functioning and evolution. This knowledge is required for the development of novel control strategies inspired by environmental mechanisms leading to desired equilibrium and dynamics in healthy ecosystems and must provide in the near future a framework for more integrated operational initiatives. PMID:29484301

Strategies for Opportunity: Creating a High Performance Workforce for Ohio. A Comprehensive Workforce Development Strategy Developed by the Governor's Human Resources Advisory Council.

ERIC Educational Resources Information Center

Ohio State Bureau of Employment Services, Columbus.

The growing gap between the skill requirements of jobs and workers' capabilities, the slow growth of the U.S. work force, and the demands of a global economy will reshape the work force in Ohio. To meet these challenges, the Governor's Human Resources Advisory Council proposes as its mission the achievement and maintenance of a high performance…

Toward a mechanistic understanding of human-induced rapid environmental change: A case study linking energy development, avian nest predation, and predators

USGS Publications Warehouse

Hethcoat, Matthew G.; Chalfoun, Anna D.

2015-01-01

Synthesis and applications. We demonstrate one mechanism, that is the local augmentation of predators, by which human-induced rapid environmental change can influence the demography of local populations. Given the accelerating trajectory of global energy demands, an important next step will be to understand why the activity and/or abundance of rodent predators increased with surrounding habitat loss from energy development activities.

Global human mandibular variation reflects differences in agricultural and hunter-gatherer subsistence strategies

PubMed Central

von Cramon-Taubadel, Noreen

2011-01-01

Variation in the masticatory behavior of hunter-gatherer and agricultural populations is hypothesized to be one of the major forces affecting the form of the human mandible. However, this has yet to be analyzed at a global level. Here, the relationship between global mandibular shape variation and subsistence economy is tested, while controlling for the potentially confounding effects of shared population history, geography, and climate. The results demonstrate that the mandible, in contrast to the cranium, significantly reflects subsistence strategy rather than neutral genetic patterns, with hunter-gatherers having consistently longer and narrower mandibles than agriculturalists. These results support notions that a decrease in masticatory stress among agriculturalists causes the mandible to grow and develop differently. This developmental argument also explains why there is often a mismatch between the size of the lower face and the dentition, which, in turn, leads to increased prevalence of dental crowding and malocclusions in modern postindustrial populations. Therefore, these results have important implications for our understanding of human masticatory adaptation. PMID:22106280

Possibilities for global governance of converging technologies

NASA Astrophysics Data System (ADS)

Roco, Mihail C.

2008-01-01

The convergence of nanotechnology, modern biology, the digital revolution and cognitive sciences will bring about tremendous improvements in transformative tools, generate new products and services, enable opportunities to meet and enhance human potential and social achievements, and in time reshape societal relationships. This paper focuses on the progress made in governance of such converging, emerging technologies and suggests possibilities for a global approach. Specifically, this paper suggests creating a multidisciplinary forum or a consultative coordinating group with members from various countries to address globally governance of converging, emerging technologies. The proposed framework for governance of converging technologies calls for four key functions: supporting the transformative impact of the new technologies; advancing responsible development that includes health, safety and ethical concerns; encouraging national and global partnerships; and establishing commitments to long-term planning and investments centered on human development. Principles of good governance guiding these functions include participation of all those who are forging or affected by the new technologies, transparency of governance strategies, responsibility of each participating stakeholder, and effective strategic planning. Introduction and management of converging technologies must be done with respect for immediate concerns, such as privacy, access to medical advancements, and potential human health effects. At the same time, introduction and management should also be done with respect for longer-term concerns, such as preserving human integrity, dignity and welfare. The suggested governance functions apply to four levels of governance: (a) adapting existing regulations and organizations; (b) establishing new programs, regulations and organizations specifically to handle converging technologies; (c) building capacity for addressing these issues into national policies and institutions; and (d) making international agreements and partnerships. Several possibilities for improving the governance of converging technologies in the global self-regulating ecosystem are recommended: using open-source and incentive-based models, establishing corresponding science and engineering platforms, empowering the stakeholders and promoting partnerships among them, implementing long-term planning that includes international perspectives, and institute voluntary and science-based measures for risk management.

Global Preparedness and Human Resources: College and Corporate Perspectives.

ERIC Educational Resources Information Center

Bikson, T. K.; Law, S. A.

A research study explored the human resource implications of the emerging economic globalism, including the following questions: How is globalism understood by corporations and colleges in the United States? What are the perceived human resource implications of globalism? and What are corporations and colleges doing today to meet these human…

From Pixels to Population Stress: Global Multispectral Remote Sensing for Vulnerable Communities

NASA Astrophysics Data System (ADS)

Prashad, L.; Kaplan, E.; Letouze, E.; Kirkpatrick, R.; Luengo-Oroz, M.; Christensen, P. R.

2011-12-01

The Arizona State University (ASU) School of Earth and Space Exploration's Mars Space Flight Facility (MSFF) and 100 Cities Project, in collaboration with the United Nations Global Pulse initiative are utilizing NASA multispectral satellite data to visualize and analyze socioeconomic characteristics and human activity in Uganda. The Global Pulse initiative is exploring how new kinds of real-time data and innovative technologies can be leveraged to detect early social impacts of slow-onset crisis and global shocks. Global Pulse is developing a framework for real-time monitoring, assembling an open-source toolkit for analyzing new kinds of data and establishing a global network of country-level "Pulse Labs" where governments, UN agencies, academia and the private sector learn together how to harness the new world of "big data" to protect the vulnerable with targeted and agile policy responses. The ASU MSFF and 100 Cities Project are coordinating with the Global Pulse team to utilize NASA remote sensing data in this effort. Human behavior and socioeconomic parameters have been successfully studied via proxy through remote sensing of the physical environment by measuring the growth of city boundaries and transportation networks, crop health, soil moisture, and slum development from visible and infrared imagery. The NASA/ NOAA image of Earth's "Lights at Night" is routinely used to estimate economic development and population density. There are many examples of the conventional uses of remote sensing in humanitarian-related projects including the Famine Early Warning System Network (FEWS NET) and the UN's operational satellite applications programme (UNOSAT), which provides remote sensing for humanitarian and disaster relief. Since the Global Pulse project is focusing on new, innovative uses of technology for early crisis detection, we are focusing on three non-conventional uses of satellite remote sensing to understand what role NASA multispectral satellites can play in monitoring underlying socioeconomic and human parameters. These are: 1) measuring and visualizing changes in agriculture and fertilizer use in Ugandan villages in order to assist policymakers in designing land use policies and evaluating the impact of fertilizer use on smallholder farmers in developing countries; 2) monitoring the size and composition of large scale rubbish dumps to determine correlation with changes in policy and economic growth; 3) measuring the size and shape of open air markets, or proxies related to the markets, to determine if changes can be detected that correspond to fluctuations in economic activity. The ASU MSFF open source geographical information systems (GIS) platform, J-Earth, will be used to provide easy access to and analytical tools for the data and imagery resulting from this project. J-Earth is a part of the Java Mission-planning and Analysis for Remote Sensing (JMARS) suite of software first developed for targeting NASA instruments on planetary missions.

Multinational corporations, the politics of the world economy, and their effects on women's health in the developing world: a review.

PubMed

Hippert, Christine

2002-12-01

Presently, globalization and the world economy maintain power relations that hamper the economic integrity and the political autonomy of the developing world. My paper addresses specific economic conditions that perpetuate poverty and poor health. I examine multinational corporations and their effects on women's health, particularly in Mexico and parts of Asia. The advent of multinational corporate business in Mexico, Malaysia, Philippines, India, and Indonesia has led to increased poverty and human rights abuses. Women bear the brunt of this because of specific international economic arrangements and their low social status, both locally and globally. As a result, their physical, mental, and emotional health is suffering. Solutions to these health problems have been proposed on multiple levels: international top-down approaches (i.e., employing international protectionist regulatory standards, exposing multinationals who infringe on their workers' human rights), as well as local grassroots organizational campaigns (i.e., conducting informational human rights workshops for factory workers). Ultimately, the answers lie in holding corporations accountable to their laborers while developing countries maintain their comparative advantage; this is the only way women's health will improve and the developing world can entice corporate investment.

Development of an International Research Project of Monsoon Asia Integrated Regional Study (MAIRS)

NASA Astrophysics Data System (ADS)

Fu, C.

2006-05-01

Monson Asia has been recommended as one of the critical regions of integrated study of global change. Among a number of reasons, the most significant features of Monsoon Asia is that this is a region where the major features of landscape, such as vegetation, soil and water system are mainly developed under the most representative monsoon climate. On the other hand, the Monsoon Asia is a region with the most active human development. It has more than 5000 years long history of civilization and highest population density of the world, reaching 57 percent of word population. It also had the most rapid development in last decades and is projected to maintain its high growth rates in the foreseeable future. The human-monsoon system interactions and their linkages with the earth system dynamics could be a challenge issue of global change research and a sustainable Asia . A science plan of MAIRS is under drafting by SSC of MAIRS under the guidance of START and an international project office of MAIRS was formally opened in IAP/Chinese Academy of Sciences under the support of Chinese government. The overall objectives of the MAIRS that will combine field experiments, process studies, and modeling components are: 1) To better understand how human activities in regions are interacting with and altering natural regional variability of the atmospheric, terrestrial, and marine components of the environment; 2) To contribute to the provision of a sound scientific basis for sustainable regional development; 3) To develop a predictive capability of estimating changes in global-regional linkages in the Earth System and to recognize on a sound scientific basis the future consequences of such changes.

[Globalization, inequality, and transmission of tropical diseases in the Venezuelan Amazon].

PubMed

Botto-Abella, Carlos; Graterol-Mendoza, Beatriz

2007-01-01

Economic globalization appears to be causing greater inequalities and increased vulnerability to tropical diseases around the world. The Venezuelan Amazon population, especially the rural indigenous population, displays among the worst health indicators in the Americas. High infant mortality rates in remote indigenous populations indicate that such communities have been affected by the globalization of disease, rather than favored by globalization of health. Globalization has also influenced public policies in the country, affecting the efficiency of control programs targeting tropical diseases. A new global pact for the sustainable development of the planet is needed, supported by the globalization of human values and rights. In Venezuela, new policies for the indigenous health sector, more resources, and greater autonomy could help reduce the inequities described here in the Venezuelan Amazon.

Planning for the Human Dimensions of Oil Spills and Spill Response

NASA Astrophysics Data System (ADS)

Webler, Thomas; Lord, Fabienne

2010-04-01

Oil spill contingency planners need an improved approach to understanding and planning for the human dimensions of oil spills. Drawing on existing literature in social impact assessment, natural hazards, human ecology, adaptive management, global change and sustainability, we develop an integrative approach to understanding and portraying the human dimensions impacts of stressors associated with oil spill events. Our approach is based on three fundamental conclusions that are drawn from this literature review. First, it is productive to acknowledge that, while stressors can produce human impacts directly, they mainly affect intermediary processes and changes to these processes produce human impacts. Second, causal chain modeling taken from hazard management literature provides a means to document how oil spill stressors change processes and produce human impacts. Third, concepts from the global change literature on vulnerability enrich causal models in ways that make more obvious how management interventions lessen hazards and mitigate associated harm. Using examples from recent spill events, we illustrate how these conclusions can be used to diagrammatically portray the human dimensions of oil spills.

EPA's Role in International Environment, Trade and Finance

EPA Pesticide Factsheets

Both domestically and globally, protecting human health and the environment is essential to sustainable economic growth and development. EPA works in trade, environment and finance to protect these goals.

Developing Sustainable Urban Water-Energy Infrastructures: Applying a Multi-Sectoral Social-Ecological-Infrastructural Systems (SEIS) Framework

NASA Astrophysics Data System (ADS)

Ramaswami, A.

2016-12-01

Urban infrastructure - broadly defined to include the systems that provide water, energy, food, shelter, transportation-communication, sanitation and green/public spaces in cities - have tremendous impact on the environment and on human well-being (Ramaswami et al., 2016; Ramaswami et al., 2012). Aggregated globally, these sectors contribute 90% of global greenhouse gas (GHG) emissions and 96% of global water withdrawals. Urban infrastructure contributions to such impacts are beginning to dominate. Cities are therefore becoming the action arena for infrastructure transformations that can achieve high levels of service delivery while reducing environmental impacts and enhancing human well-being. Achieving sustainable urban infrastructure transitions requires: information about the engineered infrastructure, and its interaction with the natural (ecological-environmental) and the social sub-systems In this paper, we apply a multi-sector, multi-scalar Social-Ecological-Infrastructural Systems framework that describes the interactions among biophysical engineered infrastructures, the natural environment and the social system in a systems-approach to inform urban infrastructure transformations. We apply the SEIS framework to inform water and energy sector transformations in cities to achieve environmental and human health benefits realized at multiple scales - local, regional and global. Local scales address pollution, health, wellbeing and inequity within the city; regional scales address regional pollution, scarcity, as well as supply risks in the water-energy sectors; global impacts include greenhouse gas emissions and climate impacts. Different actors shape infrastructure transitions including households, businesses, and policy actors. We describe the development of novel cross-sectoral strategies at the water-energy nexus in cities, focusing on water, waste and energy sectors, in a case study of Delhi, India. Ramaswami, A.; Russell, A.G.; Culligan, P.J.; Sharma, K.R.; Kumar, E. (2016). Meta-Principles for developing smart, sustainable, and healthy cities, Science, 352(6288), 940-3. Ramaswami, A., et al. A Social-Ecological Infrastructural Systems Framework for Inter-Disciplinary Study of Sustainable City-Systems. J. Ind Ecol, 16(6): 801-813, 2012.

Conservation of soil organic carbon, biodiversity and the provision of other ecosystem services along climatic gradients in West Africa

NASA Astrophysics Data System (ADS)

Marks, E.; Aflakpui, G. K. S.; Nkem, J.; Poch, R. M.; Khouma, M.; Kokou, K.; Sagoe, R.; Sebastiã, M.-T.

2009-08-01

Terrestrial carbon resources are major drivers of development in West Africa. The distribution of these resources co-varies with ecosystem type and rainfall along a strong Northeast-Southwest climatic gradient. Soil organic carbon, a strong indicator of soil quality, has been severely depleted in some areas by human activities, which leads to issues of soil erosion and desertification, but this trend can be altered with appropriate management. There is significant potential to enhance existing soil carbon stores in West Africa, with benefits at the global and local scale, for atmospheric CO2 mitigation as well as supporting and provisioning ecosystem services. Three key factors impacting carbon stocks are addressed in this review: climate, biotic factors, and human activities. Climate risks must be considered in a framework of global change, especially in West Africa, where landscape managers have few resources available to adapt to climatic perturbations. Among biotic factors, biodiversity conservation paired with carbon conservation may provide a pathway to sustainable development, and biodiversity conservation is also a global priority with local benefits for ecosystem resilience, biomass productivity, and provisioning services such as foodstuffs. Finally, human management has largely been responsible for reduced carbon stocks, but this trend can be reversed through the implementation of appropriate carbon conservation strategies in the agricultural sector, as shown by multiple studies. Owing to the strong regional climatic gradient, country-level initiatives will need to consider carbon sequestration approaches for multiple ecosystem types. Given the diversity of environments, global policies must be adapted and strategies developed at the national or sub-national levels to improve carbon storage above and belowground. Initiatives of this sort must act locally at farmer scale, and focus on ecosystem services rather than on carbon sequestration solely.

Approaches to defining deltaic sustainability in the 21st century

NASA Astrophysics Data System (ADS)

Day, John W.; Agboola, Julius; Chen, Zhongyuan; D'Elia, Christopher; Forbes, Donald L.; Giosan, Liviu; Kemp, Paul; Kuenzer, Claudia; Lane, Robert R.; Ramachandran, Ramesh; Syvitski, James; Yañez-Arancibia, Alejandro

2016-12-01

Deltas are among the most productive and economically important of global ecosystems but unfortunately they are also among the most threatened by human activities. Here we discuss deltas and human impact, several approaches to defining deltaic sustainability and present a ranking of sustainability. Delta sustainability must be considered within the context of global biophysical and socioeconomic constraints that include thermodynamic limitations, scale and embeddedness, and constraints at the level of the biosphere/geosphere. The development, functioning, and sustainability of deltas are the result of external and internal inputs of energy and materials, such as sediments and nutrients, that include delta lobe development, channel switching, crevasse formation, river floods, storms and associated waves and storm surges, and tides and other ocean currents. Modern deltas developed over the past several thousand years with relatively stable global mean sea level, predictable material inputs from drainage basins and the sea, and as extremely open systems. Human activity has changed these conditions to make deltas less sustainable, in that they are unable to persist through time structurally or functionally. Deltaic sustainability can be considered from geomorphic, ecological, and economic perspectives, with functional processes at these three levels being highly interactive. Changes in this functioning can lead to either enhanced or diminished sustainability, but most changes have been detrimental. There is a growing understanding that the trajectories of global environmental change and cost of energy will make achieving delta sustainability more challenging and limit options for management. Several delta types are identified in terms of sustainability including those in arid regions, those with high and low energy-intensive management systems, deltas below sea level, tropical deltas, and Arctic deltas. Representative deltas are ranked on a sustainability range. Success in sustainable delta management will depend on utilizing natural delta functioning and an ecological engineering approach.

People and the Arctic: A Prospectus for Research on the Human Dimensions of the Arctic System (HARC) for the National Science Foundation Arctic System Science Program.

ERIC Educational Resources Information Center

Arctic Research Consortium of the United States, Fairbanks, AK.

The U.S. Global Change Research Program was established in 1990 to develop scientific projections of anticipated impacts of the changing biosphere on humans and social systems. As part of this program, the National Science Foundation created the Arctic System Science Program (ARCSS). This document describes the ARCSS Human Dimensions of the Arctic…

GEOSS interoperability for Weather, Ocean and Water

NASA Astrophysics Data System (ADS)

Richardson, David; Nyenhuis, Michael; Zsoter, Ervin; Pappenberger, Florian

2013-04-01

"Understanding the Earth system — its weather, climate, oceans, atmosphere, water, land, geodynamics, natural resources, ecosystems, and natural and human-induced hazards — is crucial to enhancing human health, safety and welfare, alleviating human suffering including poverty, protecting the global environment, reducing disaster losses, and achieving sustainable development. Observations of the Earth system constitute critical input for advancing this understanding." With this in mind, the Group on Earth Observations (GEO) started implementing the Global Earth Observation System of Systems (GEOSS). GEOWOW, short for "GEOSS interoperability for Weather, Ocean and Water", is supporting this objective. GEOWOW's main challenge is to improve Earth observation data discovery, accessibility and exploitability, and to evolve GEOSS in terms of interoperability, standardization and functionality. One of the main goals behind the GEOWOW project is to demonstrate the value of the TIGGE archive in interdisciplinary applications, providing a vast amount of useful and easily accessible information to the users through the GEO Common Infrastructure (GCI). GEOWOW aims at developing funcionalities that will allow easy discovery, access and use of TIGGE archive data and of in-situ observations, e.g. from the Global Runoff Data Centre (GRDC), to support applications such as river discharge forecasting.TIGGE (THORPEX Interactive Grand Global Ensemble) is a key component of THORPEX: a World Weather Research Programme to accelerate the improvements in the accuracy of 1-day to 2 week high-impact weather forecasts for the benefit of humanity. The TIGGE archive consists of ensemble weather forecast data from ten global NWP centres, starting from October 2006, which has been made available for scientific research. The TIGGE archive has been used to analyse hydro-meteorological forecasts of flooding in Europe as well as in China. In general the analysis has been favourable in terms of forecast skill and concluded that the use of a multi-model forecast is beneficial. Long term analysis of individual centres, such as the European Centre for Medium-Range Weather Forecasts (ECMWF), has been conducted in the past. However, no long term and large scale study has been performed so far with inclusion of different global numerical models. Here we present some initial results from such a study.

A global strategy for road building.

PubMed

Laurance, William F; Clements, Gopalasamy Reuben; Sloan, Sean; O'Connell, Christine S; Mueller, Nathan D; Goosem, Miriam; Venter, Oscar; Edwards, David P; Phalan, Ben; Balmford, Andrew; Van Der Ree, Rodney; Arrea, Irene Burgues

2014-09-11

The number and extent of roads will expand dramatically this century. Globally, at least 25 million kilometres of new roads are anticipated by 2050; a 60% increase in the total length of roads over that in 2010. Nine-tenths of all road construction is expected to occur in developing nations, including many regions that sustain exceptional biodiversity and vital ecosystem services. Roads penetrating into wilderness or frontier areas are a major proximate driver of habitat loss and fragmentation, wildfires, overhunting and other environmental degradation, often with irreversible impacts on ecosystems. Unfortunately, much road proliferation is chaotic or poorly planned, and the rate of expansion is so great that it often overwhelms the capacity of environmental planners and managers. Here we present a global scheme for prioritizing road building. This large-scale zoning plan seeks to limit the environmental costs of road expansion while maximizing its benefits for human development, by helping to increase agricultural production, which is an urgent priority given that global food demand could double by mid-century. Our analysis identifies areas with high environmental values where future road building should be avoided if possible, areas where strategic road improvements could promote agricultural development with relatively modest environmental costs, and 'conflict areas' where road building could have sizeable benefits for agriculture but with serious environmental damage. Our plan provides a template for proactively zoning and prioritizing roads during the most explosive era of road expansion in human history.

Drivers for the emergence and re-emergence of vector-borne protozoal and bacterial diseases.

PubMed

Harrus, S; Baneth, G

2005-10-01

In recent years, vector-borne parasitic and bacterial diseases have emerged or re-emerged in many geographical regions causing global health and economic problems that involve humans, livestock, companion animals and wild life. The ecology and epidemiology of vector-borne diseases are affected by the interrelations between three major factors comprising the pathogen, the host (human, animal or vector) and the environment. Important drivers for the emergence and spread of vector-borne parasites include habitat changes, alterations in water storage and irrigation habits, atmospheric and climate changes, immunosuppression by HIV, pollution, development of insecticide and drug resistance, globalization and the significant increase in international trade, tourism and travel. War and civil unrest, and governmental or global management failure are also major contributors to the spread of infectious diseases. The improvement of epidemic understanding and planning together with the development of new diagnostic molecular techniques in the last few decades have allowed researchers to better diagnose and trace pathogens, their origin and routes of infection, and to develop preventive public health and intervention programs. Health care workers, physicians, veterinarians and biosecurity officers should play a key role in future prevention of vector-borne diseases. A coordinated global approach for the prevention of vector-borne diseases should be implemented by international organizations and governmental agencies in collaboration with research institutions.

An International Strategy for Human Exploration of the Moon: The International Space Exploration Coordination Group (ISECG) Reference Architecture for Human Lunar Exploration

NASA Technical Reports Server (NTRS)

Laurini, Kathleen C.; Hufenbach, Bernhard; Junichiro, Kawaguchi; Piedboeuf, Jean-Claude; Schade, Britta; Lorenzoni, Andrea; Curtis, Jeremy; Hae-Dong, Kim

2010-01-01

The International Space Exploration Coordination Group (ISECG) was established in response to The Global Exploration Strategy: The Framework for Coordination developed by fourteen space agencies and released in May 2007. Several ISECG participating space agencies have been studying concepts for human exploration of the moon that allow individual and collective goals and objectives to be met. This 18 month study activity culminated with the development of the ISECG Reference Architecture for Human Lunar Exploration. The reference architecture is a series of elements delivered over time in a flexible and evolvable campaign. This paper will describe the reference architecture and how it will inform near-term and long-term programmatic planning within interested agencies. The reference architecture is intended to serve as a global point of departure conceptual architecture that enables individual agency investments in technology development and demonstration, International Space Station research and technology demonstration, terrestrial analog studies, and robotic precursor missions to contribute towards the eventual implementation of a human lunar exploration scenario which reflects the concepts and priorities established to date. It also serves to create opportunities for partnerships that will support evolution of this concept and its eventual realization. The ISECG Reference Architecture for Human Lunar Exploration (commonly referred to as the lunar gPoD) reflects the agency commitments to finding an effective balance between conducting important scientific investigations of and from the moon, as well as demonstrating and mastering the technologies and capabilities to send humans farther into the Solar System. The lunar gPoD begins with a robust robotic precursor phase that demonstrates technologies and capabilities considered important for the success of the campaign. Robotic missions will inform the human missions and buy down risks. Human exploration will start with a thorough scientific investigation of the polar region while allowing the ability to demonstrate and validate the systems needed to take humans on more ambitious lunar exploration excursions. The ISECG Reference Architecture for Human Lunar Exploration serves as a model for future cooperation and is documented in a summary report and a comprehensive document that also describes the collaborative international process that led to its development. ISECG plans to continue with architecture studies such as this to examine an open transportation architecture and other destinations, with expanded participation from ISECG agencies, as it works to inform international partnerships and advance the Global Exploration Strategy.

A model for upscaling global partnerships and building nurse and midwifery capacity.

PubMed

Spies, L A; Garner, S L; Faucher, M A; Hastings-Tolsma, M; Riley, C; Millenbruch, J; Prater, L; Conroy, S F

2017-09-01

To provide a unique model for use in guiding global collaboration and policy to upscale nursing and midwifery partnerships. Nurses and midwives across nations need skills reaching beyond the bedside and unit level in today's complex, global, multifaceted healthcare milieu. Thoughtful consideration, research and concomitant development of models to guide appropriate upscaling of nurse and midwifery capacity within and between nations are needed. This article explores an integrated global approach to upscaling nurse and midwifery capacity using examples of partnerships between nursing and midwifery programmes across multiple continents. Global nurse and midwifery capacity is effectively being developed using a myriad of approaches. A new model is presented to illustrate supports, strategies and activities to achieve intermediate and long-term goals for capacity building through strong and sustainable global partnerships. Development of global skills can focus the nurse and midwife to influence policy-level decisions. Human resource planning that can impact countrywide provision of health care begins in the preservice setting for both nurses and midwives. A global experience can be a value-added component to the well-rounded education of future nurses. Education during preparation for entry into practice is a strategic way to develop a worldview. Incorporating reflective practice can build skills and shape attitudes to prepare the new nurse to be comfortable as a global healthcare provider. An expanded world view is the springboard to more robust and informed involvement and inclusion in policy-level discussions. © 2017 International Council of Nurses.

Impacts of conservation and human development policy across stakeholders and scales.

PubMed

Li, Cong; Zheng, Hua; Li, Shuzhuo; Chen, Xiaoshu; Li, Jie; Zeng, Weihong; Liang, Yicheng; Polasky, Stephen; Feldman, Marcus W; Ruckelshaus, Mary; Ouyang, Zhiyun; Daily, Gretchen C

2015-06-16

Ideally, both ecosystem service and human development policies should improve human well-being through the conservation of ecosystems that provide valuable services. However, program costs and benefits to multiple stakeholders, and how they change through time, are rarely carefully analyzed. We examine one of China's new ecosystem service protection and human development policies: the Relocation and Settlement Program of Southern Shaanxi Province (RSP), which pays households who opt voluntarily to resettle from mountainous areas. The RSP aims to reduce disaster risk, restore important ecosystem services, and improve human well-being. We use household surveys and biophysical data in an integrated economic cost-benefit analysis for multiple stakeholders. We project that the RSP will result in positive net benefits to the municipal government, and to cross-region and global beneficiaries over the long run along with environment improvement, including improved water quality, soil erosion control, and carbon sequestration. However, there are significant short-run relocation costs for local residents so that poor households may have difficulty participating because they lack the resources to pay the initial costs of relocation. Greater subsidies and subsequent supports after relocation are necessary to reduce the payback period of resettled households in the long run. Compensation from downstream beneficiaries for improved water and from carbon trades could be channeled into reducing relocation costs for the poor and sharing the burden of RSP implementation. The effectiveness of the RSP could also be greatly strengthened by early investment in developing human capital and environment-friendly jobs and establishing long-term mechanisms for securing program goals. These challenges and potential solutions pervade ecosystem service efforts globally.

Socioeconomic contexts of primate conservation: population, poverty, global economic demands, and sustainable land use.

PubMed

Estrada, Alejandro

2013-01-01

Recent assessments by the International Union for Conservation of Nature (IUCN) indicate the existence of about 612 recognized primate species and subspecies (IUCN RedList, 2012), but close to 50% of these taxa are at risk of extinction as a result of human action. In this article, I call attention to underlying regional and global socioeconomic contexts of primate conservation. Using information from FAO and UN databases and other sources, I examine, for the Neotropics, sub-Saharan Africa, and Southeast Asia, trends in forest loss and human demographics and social condition, discuss the impact of global market pressures upon primate habitats, and examine land-use patterns that may favor primate conservation. Between 1990 and 2010, an estimated 149 million ha of forest were lost in the three regions and additional losses are expected in the future. Global human population will increase from 7 billion in 2012 to 9 billion in 2050. Currently, 2 billion people live in the three primate range regions under high levels of poverty. Large-scale deforestation is related to global market demands, especially from developed and developing nations, for food (e.g., cattle), domestic animal feed (e.g., soybeans), biofuel-based crops (e.g., oil palm), and industrial round wood. The growth of protected areas in the three regions has been steady for several decades, but it is not enough to ensure long-term conservation of many primate taxa. Other conservations tools involving sustainable land use and biodiversity conservation corridors are required at the landscape level. The above assessment can easily be applied at the local level by primatologists, giving more precision to conservation initiatives. © 2012 Wiley Periodicals, Inc.

Sarilumab for the treatment of rheumatoid arthritis.

PubMed

Cooper, Simon

2016-01-01

Simon Cooper has >18 years of global experience in the pharmaceutical industry. He joined Sanofi in July 2014 as the Vice President, Global Project Head. In his current position at Sanofi, Dr Cooper is responsible for the clinical development of sarilumab and the worldwide submission in rheumatoid arthritis. He joined Sanofi after serving as the Global Program Medical Director at Novartis since 2012. In this role, Dr Cooper acted as the clinical lead for secukinumab psoriasis submission. Prior to Novartis, Dr Cooper held various posts at Human Genome Sciences, USA, including Executive Director of Clinical Research, Senior Director of Clinical Research and Director of Clinical Research. During his tenure at Human Genome Sciences, USA, Dr Cooper was involved in the submission of belimumab leading to its approval for SLE, and was responsible for its subsequent clinical development program. Dr Cooper has also previously held positions at MedImmune Ltd, UK, Roche, Napp Pharmaceutical Research Ltd, Wyeth Research and Medeval Ltd. In these roles, his responsibilities ranged from medical oversight of clinical trials to medical support for commercial, medical affairs and business development. He received a Bachelor of Medicine and Bachelor of Surgery from University of Newcastle upon Tyne Medical School.

Socioeconomic status is associated with global diabetes prevalence

PubMed Central

Xu, Zhiye; Yu, Dan; Yin, Xueyao; Zheng, Fenping; Li, Hong

2017-01-01

The incidence of diabetes is increasing globally. We investigated the relationship between diabetes prevalence and patient socioeconomic status across multiple countries. We searched PubMed to identify population-based surveys reporting diabetes prevalence between 1990 and May 2016. Search results were filtered, and Human Development Index (HDI) values from the United Nations Development Programme were used to assess socioeconomic status for a given nation. Our analysis included 45 national surveys from 32 countries. Diabetes prevalence was positively correlated with national HDI (r = 0.421 P = 0.041) in developing countries, and negatively correlated with HDI (r = −0.442 P = 0.045) in developed countries. Diabetes prevalence trends were the same in women and men, although men were associated with increased diabetes risk in developed countries (r = 0.459 P = 0.048). Thus, diabetes prevalence rises with increasing HDI in developing countries, and this is reversed in developed countries. Ours is the first study to investigate the relationship between diabetes and socioeconomic status at global level using HDI values. These results will aid in evaluating global diabetes prevalence and risk with respect to patient socioeconomic status, and will be useful in the development of policies that help reduce disease incidence. PMID:28574844

Socioeconomic status is associated with global diabetes prevalence.

PubMed

Xu, Zhiye; Yu, Dan; Yin, Xueyao; Zheng, Fenping; Li, Hong

2017-07-04

The incidence of diabetes is increasing globally. We investigated the relationship between diabetes prevalence and patient socioeconomic status across multiple countries. We searched PubMed to identify population-based surveys reporting diabetes prevalence between 1990 and May 2016. Search results were filtered, and Human Development Index (HDI) values from the United Nations Development Programme were used to assess socioeconomic status for a given nation. Our analysis included 45 national surveys from 32 countries. Diabetes prevalence was positively correlated with national HDI (r = 0.421 P = 0.041) in developing countries, and negatively correlated with HDI (r = -0.442 P = 0.045) in developed countries. Diabetes prevalence trends were the same in women and men, although men were associated with increased diabetes risk in developed countries (r = 0.459 P = 0.048). Thus, diabetes prevalence rises with increasing HDI in developing countries, and this is reversed in developed countries. Ours is the first study to investigate the relationship between diabetes and socioeconomic status at global level using HDI values. These results will aid in evaluating global diabetes prevalence and risk with respect to patient socioeconomic status, and will be useful in the development of policies that help reduce disease incidence.

Need for ICT Integration for Effective Instructional Delivery in Nigerian Colleges of Education

ERIC Educational Resources Information Center

Onwuagboke, Bede Blaise Chukwunyere; Singh, Termit Kaur Ranjit; Fook, Fong Soon

2015-01-01

Teaching and learning is the principal stock in trade of any educational enterprise throughout human history whether in the developed, developing or under-developed countries. The various developments in the field of information and communications technology (ICT) have been found very useful in the learning environment globally. The need to fully…

Comprehensive Hands-on Training for Influenza Vaccine Manufacturing: A WHO-BARDA-BTEC Partnership for Global Workforce Development

ERIC Educational Resources Information Center

Ruiz, Jennifer; Gilleskie, Gary L.; Brown, Patty; Burnett, Bruce; Carbonell, Ruben G.

2014-01-01

The critical need for enhancing influenza pandemic preparedness in many developing nations has led the World Health Organization (WHO) and the Biomedical Advanced Research and Development Authority (BARDA), part of the U.S. Department of Health and Human Services (HHS), to develop an international influenza vaccine capacity-building program. Among…

Global models underestimate large decadal declining and rising water storage trends relative to GRACE satellite data

PubMed Central

Scanlon, Bridget R.; Zhang, Zizhan; Save, Himanshu; Sun, Alexander Y.; van Beek, Ludovicus P. H.; Wiese, David N.; Reedy, Robert C.; Longuevergne, Laurent; Döll, Petra; Bierkens, Marc F. P.

2018-01-01

Assessing reliability of global models is critical because of increasing reliance on these models to address past and projected future climate and human stresses on global water resources. Here, we evaluate model reliability based on a comprehensive comparison of decadal trends (2002–2014) in land water storage from seven global models (WGHM, PCR-GLOBWB, GLDAS NOAH, MOSAIC, VIC, CLM, and CLSM) to trends from three Gravity Recovery and Climate Experiment (GRACE) satellite solutions in 186 river basins (∼60% of global land area). Medians of modeled basin water storage trends greatly underestimate GRACE-derived large decreasing (≤−0.5 km3/y) and increasing (≥0.5 km3/y) trends. Decreasing trends from GRACE are mostly related to human use (irrigation) and climate variations, whereas increasing trends reflect climate variations. For example, in the Amazon, GRACE estimates a large increasing trend of ∼43 km3/y, whereas most models estimate decreasing trends (−71 to 11 km3/y). Land water storage trends, summed over all basins, are positive for GRACE (∼71–82 km3/y) but negative for models (−450 to −12 km3/y), contributing opposing trends to global mean sea level change. Impacts of climate forcing on decadal land water storage trends exceed those of modeled human intervention by about a factor of 2. The model-GRACE comparison highlights potential areas of future model development, particularly simulated water storage. The inability of models to capture large decadal water storage trends based on GRACE indicates that model projections of climate and human-induced water storage changes may be underestimated. PMID:29358394

Global models underestimate large decadal declining and rising water storage trends relative to GRACE satellite data.

PubMed

Scanlon, Bridget R; Zhang, Zizhan; Save, Himanshu; Sun, Alexander Y; Müller Schmied, Hannes; van Beek, Ludovicus P H; Wiese, David N; Wada, Yoshihide; Long, Di; Reedy, Robert C; Longuevergne, Laurent; Döll, Petra; Bierkens, Marc F P

2018-02-06

Assessing reliability of global models is critical because of increasing reliance on these models to address past and projected future climate and human stresses on global water resources. Here, we evaluate model reliability based on a comprehensive comparison of decadal trends (2002-2014) in land water storage from seven global models (WGHM, PCR-GLOBWB, GLDAS NOAH, MOSAIC, VIC, CLM, and CLSM) to trends from three Gravity Recovery and Climate Experiment (GRACE) satellite solutions in 186 river basins (∼60% of global land area). Medians of modeled basin water storage trends greatly underestimate GRACE-derived large decreasing (≤-0.5 km 3 /y) and increasing (≥0.5 km 3 /y) trends. Decreasing trends from GRACE are mostly related to human use (irrigation) and climate variations, whereas increasing trends reflect climate variations. For example, in the Amazon, GRACE estimates a large increasing trend of ∼43 km 3 /y, whereas most models estimate decreasing trends (-71 to 11 km 3 /y). Land water storage trends, summed over all basins, are positive for GRACE (∼71-82 km 3 /y) but negative for models (-450 to -12 km 3 /y), contributing opposing trends to global mean sea level change. Impacts of climate forcing on decadal land water storage trends exceed those of modeled human intervention by about a factor of 2. The model-GRACE comparison highlights potential areas of future model development, particularly simulated water storage. The inability of models to capture large decadal water storage trends based on GRACE indicates that model projections of climate and human-induced water storage changes may be underestimated. Copyright © 2018 the Author(s). Published by PNAS.

Global change pressures on soils from land use and management.

PubMed

Smith, Pete; House, Joanna I; Bustamante, Mercedes; Sobocká, Jaroslava; Harper, Richard; Pan, Genxing; West, Paul C; Clark, Joanna M; Adhya, Tapan; Rumpel, Cornelia; Paustian, Keith; Kuikman, Peter; Cotrufo, M Francesca; Elliott, Jane A; McDowell, Richard; Griffiths, Robert I; Asakawa, Susumu; Bondeau, Alberte; Jain, Atul K; Meersmans, Jeroen; Pugh, Thomas A M

2016-03-01

Soils are subject to varying degrees of direct or indirect human disturbance, constituting a major global change driver. Factoring out natural from direct and indirect human influence is not always straightforward, but some human activities have clear impacts. These include land-use change, land management and land degradation (erosion, compaction, sealing and salinization). The intensity of land use also exerts a great impact on soils, and soils are also subject to indirect impacts arising from human activity, such as acid deposition (sulphur and nitrogen) and heavy metal pollution. In this critical review, we report the state-of-the-art understanding of these global change pressures on soils, identify knowledge gaps and research challenges and highlight actions and policies to minimize adverse environmental impacts arising from these global change drivers. Soils are central to considerations of what constitutes sustainable intensification. Therefore, ensuring that vulnerable and high environmental value soils are considered when protecting important habitats and ecosystems, will help to reduce the pressure on land from global change drivers. To ensure that soils are protected as part of wider environmental efforts, a global soil resilience programme should be considered, to monitor, recover or sustain soil fertility and function, and to enhance the ecosystem services provided by soils. Soils cannot, and should not, be considered in isolation of the ecosystems that they underpin and vice versa. The role of soils in supporting ecosystems and natural capital needs greater recognition. The lasting legacy of the International Year of Soils in 2015 should be to put soils at the centre of policy supporting environmental protection and sustainable development. © 2015 John Wiley & Sons Ltd.

Constructing Patriotism: Teaching History and Memories in Global Worlds. Advances in Cultural Psychology: Constructing Human Development

ERIC Educational Resources Information Center

Carretero, Mario

2011-01-01

Memory construction and national identity are key issues in our societies, as well as it is patriotism. How can we nowadays believe and give sense to traditional narrations that explain the origins of nations and communities? How do these narrations function in a process of globalization? How should we remember the recent past? In the construction…

Learning from Our Global Competitors: A Comparative Analysis of Science, Technology, Engineering and Mathematics (STEM) Education Pipelines in the United States, Mainland China and Taiwan

ERIC Educational Resources Information Center

Chow, Christina M.

2011-01-01

Maintaining a competitive edge within the 21st century is dependent on the cultivation of human capital, producing qualified and innovative employees capable of competing within the new global marketplace. Technological advancements in communications technology as well as large scale, infrastructure development has led to a leveled playing field…

Towards realistic Holocene land cover scenarios: integration of archaeological, palynological and geomorphological records and comparison to global land cover scenarios.

NASA Astrophysics Data System (ADS)

De Brue, Hanne; Verstraeten, Gert; Broothaerts, Nils; Notebaert, Bastiaan

2016-04-01

Accurate and spatially explicit landscape reconstructions for distinct time periods in human history are essential for the quantification of the effect of anthropogenic land cover changes on, e.g., global biogeochemical cycles, ecology, and geomorphic processes, and to improve our understanding of interaction between humans and the environment in general. A long-term perspective covering Mid and Late Holocene land use changes is recommended in this context, as it provides a baseline to evaluate human impact in more recent periods. Previous efforts to assess the evolution and intensity of agricultural land cover in past centuries or millennia have predominantly focused on palynological records. An increasing number of quantitative techniques has been developed during the last two decades to transfer palynological data to land cover estimates. However, these techniques have to deal with equifinality issues and, furthermore, do not sufficiently allow to reconstruct spatial patterns of past land cover. On the other hand, several continental and global databases of historical anthropogenic land cover changes based on estimates of global population and the required agricultural land per capita have been developed in the past decennium. However, at such long temporal and spatial scales, reconstruction of past anthropogenic land cover intensities and spatial patterns necessarily involves many uncertainties and assumptions as well. Here, we present a novel approach that combines archaeological, palynological and geomorphological data for the Dijle catchment in the central Belgium Loess Belt in order to arrive at more realistic Holocene land cover histories. Multiple land cover scenarios (> 60.000) are constructed using probabilistic rules and used as input into a sediment delivery model (WaTEM/SEDEM). Model outcomes are confronted with a detailed geomorphic dataset on Holocene sediment fluxes and with REVEALS based estimates of vegetation cover using palynological data from six alluvial sites. This comparison drastically reduces the number of realistic land cover scenarios for various cultural periods. REVEALS based land cover histories provide more accurate estimates of Holocene sediment fluxes compared to global land cover scenarios (KK10 and HYDE 3.1). Both global land cover scenarios produce erroneous results when applied at their original coarse scale resolution. However, spatially allocating KK10 land cover data to a finer spatial resolution increases its performance, whereas this is not the case for HYDE 3.1. Results suggest that KK10 also offers a more realistic history of human impact than HYDE 3.1 although it overestimates human impact in the Belgian Loess Belt prior to the Roman Age, whereas it underestimates human impact from the Medieval Period onwards.

Understanding Global Change: A New Conceptual Framework To Guide Teaching About Planetary Systems And Both The Causes And Effects Of Changes In Those Systems

NASA Astrophysics Data System (ADS)

Levine, J.; Bean, J. R.

2016-12-01

Goals of the Next Generation Science Standards include understanding climate change and learning about ways to moderate the causes and mitigate the consequences of planetary-scale anthropogenic activities that interact synergistically to affect ecosystems and societies. The sheer number and scale of both causes and effects of global change can be daunting for teachers, and the lack of a clear conceptual framework for presenting this material usually leads educators (and textbooks) to present these phenomenon as a disjointed "laundry list." But an alternative approach is in the works. The Understanding Global Change web resource, currently under development at the UC Berkeley Museum of Paleontology, will provide educators with a conceptual framework, graphic models, lessons, and assessment templates for teaching NGSS-aligned, interdisciplinary, global change curricula. The core of this resource is an original informational graphic that presents and relates Earth's global systems, human and non-human factors that produce changes in those systems, and the effects of those changes that scientists can measure.

Global Human Appropriation of Net Primary Production and Associated Resource Decoupling: 2010-2050.

PubMed

Zhou, Chuanbin; Elshkaki, Ayman; Graedel, T E

2018-02-06

Human appropriation of net primary production (HANPP) methodology has previously been developed to assess the intensity of anthropogenic extraction of biomass resources. However, there is limited analysis concerning future trends of HANPP. Here we present four scenarios for global biomass demand and HANPP harv (the most key component of HANPP) from 2010 to 2050 by incorporating data on expanded historical drivers and disaggregated biomass demand (food, wood material, and fuelwood). The results show that the biomass demand has the lowest value in the equitability world scenario (an egalitarian vision) and the highest value in the security foremost scenario (an isolationist vision). The biomass demand for food and materials increases over time, while fuelwood demand decreases over time. Global HANPP harv rises to between 8.5 and 10.1 Pg C/yr in 2050 in the four scenarios, 14-35% above its value in 2010, and some 50% of HANPP harv is calculated to be crop residues, wood residues, and food losses in the future. HANPP harv in developing regions (Asia, Africa, and Latin America) increases faster than that in more-developed regions (North America and Europe), due to urbanization, population growth, and increasing income. Decoupling of HANPP harv and socioeconomic development is also discussed in this work.

Does Global Progress on Sanitation Really Lag behind Water? An Analysis of Global Progress on Community- and Household-Level Access to Safe Water and Sanitation

PubMed Central

Cumming, Oliver; Elliott, Mark; Overbo, Alycia; Bartram, Jamie

2014-01-01

Safe drinking water and sanitation are important determinants of human health and wellbeing and have recently been declared human rights by the international community. Increased access to both were included in the Millennium Development Goals under a single dedicated target for 2015. This target was reached in 2010 for water but sanitation will fall short; however, there is an important difference in the benchmarks used for assessing global access. For drinking water the benchmark is community-level access whilst for sanitation it is household-level access, so a pit latrine shared between households does not count toward the Millennium Development Goal (MDG) target. We estimated global progress for water and sanitation under two scenarios: with equivalent household- and community-level benchmarks. Our results demonstrate that the “sanitation deficit” is apparent only when household-level sanitation access is contrasted with community-level water access. When equivalent benchmarks are used for water and sanitation, the global deficit is as great for water as it is for sanitation, and sanitation progress in the MDG-period (1990–2015) outstrips that in water. As both drinking water and sanitation access yield greater benefits at the household-level than at the community-level, we conclude that any post–2015 goals should consider a household-level benchmark for both. PMID:25502659

Does global progress on sanitation really lag behind water? An analysis of global progress on community- and household-level access to safe water and sanitation.

PubMed

Cumming, Oliver; Elliott, Mark; Overbo, Alycia; Bartram, Jamie

2014-01-01

Safe drinking water and sanitation are important determinants of human health and wellbeing and have recently been declared human rights by the international community. Increased access to both were included in the Millennium Development Goals under a single dedicated target for 2015. This target was reached in 2010 for water but sanitation will fall short; however, there is an important difference in the benchmarks used for assessing global access. For drinking water the benchmark is community-level access whilst for sanitation it is household-level access, so a pit latrine shared between households does not count toward the Millennium Development Goal (MDG) target. We estimated global progress for water and sanitation under two scenarios: with equivalent household- and community-level benchmarks. Our results demonstrate that the "sanitation deficit" is apparent only when household-level sanitation access is contrasted with community-level water access. When equivalent benchmarks are used for water and sanitation, the global deficit is as great for water as it is for sanitation, and sanitation progress in the MDG-period (1990-2015) outstrips that in water. As both drinking water and sanitation access yield greater benefits at the household-level than at the community-level, we conclude that any post-2015 goals should consider a household-level benchmark for both.

Graduate public health training in healthcare of refugee asylum seekers and clinical human rights: evaluation of an innovative curriculum.

PubMed

Asgary, Ramin

2016-04-01

An innovative curriculum was developed to equip public health students with appropriate attitude and skills to address healthcare of asylum seekers. Implemented in 2005 the curriculum included: (1) didactic sessions covering epidemiology and health sequelae of torture, asylum laws, and approaches to identify survivors' healthcare needs; (2) panel discussions with survivors and advocates; and (3) participating in medico-legal process of asylum seeking. Complementary mixed methods evaluations included pre- and post-curriculum questionnaires, formal curriculum evaluations, final papers and oral presentations. 125 students participated. Students showed improved knowledge regrading sequelae of abuse and survivors' healthcare needs (P < 0.01), improved attitudes towards working with survivors (P < 0.05) and self-efficacy in identifying at-risk populations and addressing healthcare of survivors (P < 0.05). Students reported increased desire to pursue global health and human rights careers. As an advocacy and cultural competency training in public health practice addressing healthcare of refugees domestically, this curriculum was well received and effective, and will also help students better serve other similar populations. Population case-based domestic opportunities to teach global health and health and human rights should be effectively utilized to develop a well-equipped global health corps.

Advances in development reverse fertility declines.

PubMed

Myrskylä, Mikko; Kohler, Hans-Peter; Billari, Francesco C

2009-08-06

During the twentieth century, the global population has gone through unprecedented increases in economic and social development that coincided with substantial declines in human fertility and population growth rates. The negative association of fertility with economic and social development has therefore become one of the most solidly established and generally accepted empirical regularities in the social sciences. As a result of this close connection between development and fertility decline, more than half of the global population now lives in regions with below-replacement fertility (less than 2.1 children per woman). In many highly developed countries, the trend towards low fertility has also been deemed irreversible. Rapid population ageing, and in some cases the prospect of significant population decline, have therefore become a central socioeconomic concern and policy challenge. Here we show, using new cross-sectional and longitudinal analyses of the total fertility rate and the human development index (HDI), a fundamental change in the well-established negative relationship between fertility and development as the global population entered the twenty-first century. Although development continues to promote fertility decline at low and medium HDI levels, our analyses show that at advanced HDI levels, further development can reverse the declining trend in fertility. The previously negative development-fertility relationship has become J-shaped, with the HDI being positively associated with fertility among highly developed countries. This reversal of fertility decline as a result of continued economic and social development has the potential to slow the rates of population ageing, thereby ameliorating the social and economic problems that have been associated with the emergence and persistence of very low fertility.

Establishment of Institutional Policies for Enhancing Education Quality in Cambodian Universities

ERIC Educational Resources Information Center

Rany, Sam; Zain, Ahmad Nurulazam Md; Jamil, Hazri

2012-01-01

In the context of global and national economic development, higher education in Cambodia plays a significant role to develop human capital with technical knowledge, skills, values, and attitudes for sustainable economic growth, social development, and alleviation of poverty. When the civil war in 1998 was over, the Royal Government of Cambodia…

Heterarchical Coaching for Continuing Teacher Professional Learning and Development: A Transversal Analysis of Agency

ERIC Educational Resources Information Center

Charteris, Jennifer; Smardon, Dianne; Foulkes, Ruth; Bewley, Sue

2017-01-01

Aligned with the development of human capital, in-service teacher education is globally conceived as a key lever in economic development. However, teacher education is also a critically important process to leverage teacher political awareness and social justice. This article provides a socio-materialist account of continuous professional…

Engineers, Development, and Engineering Education: From National to Sustainable Community Development

ERIC Educational Resources Information Center

Lucena, J.; Schneider, J.

2008-01-01

In October 2007, Norman Borlaug wrote in "Science" magazine that "more than 200 science journals throughout the world will simultaneously publish papers on global poverty and human development--a collaborative effort to increase awareness, interest, and research about these important issues of our time". Borlaug, Nobel Peace Prize laureate and…

Growth charts of human development.

PubMed

van Buuren, Stef

2014-08-01

This article reviews and compares two types of growth charts for tracking human development over age. Both charts assume the existence of a continuous latent variable, but relate to the observed data in different ways. The D-score diagram summarizes developmental indicators into a single aggregate score measuring global development. The relations between the indicators should be consistent with the Rasch model. If true, the D-score is a measure with interval scale properties, and allows for the calculation of meaningful differences both within and across age. The stage line diagram describes the natural development of ordinal indicators. The method models the transition probabilities between successive stages of the indicator as smoothly varying functions of age. The location of each stage is quantified by the mid-P-value. Both types of diagrams assist in identifying early and delayed development, as well as finding differences in tempo. The relevant techniques are illustrated to track global development during infancy and early childhood (0-2 years) and Tanner pubertal stages (8-21 years). New reference values for both applications are provided. © The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

Modelling energy and environmental impacts of traditional and improved shea butter production in West Africa for food security.

PubMed

Naughton, Colleen C; Zhang, Qiong; Mihelcic, James R

2017-01-15

This study improves the global application of methods and analyses, especially Life Cycle Assessment (LCA), that properly incorporates environmental impacts of firewood and a social sustainability indicator (human energy) as tools for sustainable human development. Specifically shea butter production processes, common throughout sub-Saharan Africa and crucial to food security, environmental sustainability, and women's empowerment, are analyzed. Many economic activities in the world rely on firewood for energy and labor that aren't included in traditional LCAs. Human energy (entirely from women) contributed 25-100% of shea butter production processes (2000-6100kJ/kg of shea butter) and mechanized production processes had reduced human energy without considerably greater total energy. Firewood accounted for 94-100% of total embodied energy (103 and 172MJ/kg of shea butter for improved and traditional shea butter production processes respectively) and global warming potential and 18-100% of human toxicity of the production processes. Implementation of improved cookstoves modeled in this study could reduce: (1) global warming potential by 78% (from 18 to 4.1kg CO 2 eq/kg and 11 to 2.4kg CO 2 eq/kg of shea butter for the traditional and improved processes respectively), (2) the embodied energy of using firewood by 52% (from 170 to 82MJ/kg and 103 to 49MJ/kg for the traditional and improved processes respectively), and (3) human toxicity by 83% for the non-mechanized traditional and improved processes (from 0.041 to 0.0071 1,4 DB eq/kg and 0.025 to 0.0042 1,4 DB eq/kg respectively). In addition, this is the first study to compare Economic Input-Output Life Cycle Assessment (EIO-LCA) and process-based LCA in a developing country and evaluate five traditional and improved shea butter production processes over different impact categories. Overall, this study developed a framework to evaluate and improve processes for achievement of the United Nation's Sustainable Development Goals for 2030 particularly to obtain food security. Copyright © 2016 Elsevier B.V. All rights reserved.

Global Governance for Health: how to motivate political change?

PubMed

McNeill, D; Ottersen, O P

2015-07-01

In this article, we address a central theme that was discussed at the Durham Health Summit: how can politics be brought back into global health governance and figure much more prominently in discussions around policy? We begin by briefly summarizing the report of the Lancet - University of Oslo Commission on Global Governance for Health: 'The Political Origins of Health Inequity' Ottersen et al. In order to provide compelling evidence of the central argument, the Commission selected seven case studies relating to, inter alia, economic and fiscal policy, food security, and foreign trade and investment agreements. Based on an analysis of these studies, the report concludes that the problems identified are often due to political choices: an unwillingness to change the global system of governance. This raises the question: what is the most effective way that a report of this kind can be used to motivate policy-makers, and the public at large, to demand change? What kind of moral or rational argument is most likely to lead to action? In this paper we assess the merits of various alternative perspectives: health as an investment; health as a global public good; health and human security; health and human development; health as a human right; health and global justice. We conclude that what is required in order to motivate change is a more explicitly political and moral perspective - favouring the later rather than the earlier alternatives just listed. Copyright © 2015 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

Developing Enterprise E-Learning at Kodak.

ERIC Educational Resources Information Center

Gold, Martha

2003-01-01

The third in a five-part series of case studies on enterprisewide electronic learning describes how Kodak's approach to a global learning management system integrated 80 discrete human resource systems into one. (JOW)

The Quest for Cognitive Justice: Towards a Pluriversal Human Rights Education

ERIC Educational Resources Information Center

Zembylas, Michalinos

2017-01-01

This paper turns to the work of the Portuguese sociologist Boaventura de Sousa Santos and explores how a set of concepts he developed over the years may constitute valuable tools in the task of decolonising and pluriversalising Human Rights Education (HRE). Informed by decolonial theory, Santos highlights that the struggle for global social…

Human Resource Development Practices, Managers and Multinational Enterprises in Australia: Thinking Globally, Acting Locally

ERIC Educational Resources Information Center

Sablok, Gitika; Stanton, Pauline; Bartram, Timothy; Burgess, John; Boyle, Brendan

2017-01-01

Purpose: The purpose of this paper is to examine the HRD practices of multinational enterprises (MNEs) operating in Australia to understand the value that MNEs place on investment in their human capital, particularly managerial talent. Design/methodology/approach: Drawing on a representative sample of 211 MNEs operating in Australia, this paper…

Schooling for Humanity: When Big Brother Isn't Watching.

ERIC Educational Resources Information Center

Solmitz, David O.

Most educational reform initiatives of the past 20 years are geared towards ensuring that the United States dominates the emerging global economy. What is lost in this rush to the top of the materialist heap is an education for the more enduring human values: creativity, intellectual development, care, social justice, and democracy. In this book,…

Democracy is a historical urgency

NASA Astrophysics Data System (ADS)

Synek, Miroslav

2014-03-01

Survival of human society on this planet depends heavily on coping with advanced nuclear technological development. Democracy is a historical urgency, in the age of intercontinental nuclear missiles, computerized on a push-button, conceivably controllable by a miscalculating, suicidal and very powerful dictator, producing a global nuclear holocaust, on our entire planet. Diplomacy should help humanity to approach the contemporary situation.

World Trends and Alternative Futures. Open Grants Papers No. 1.

ERIC Educational Resources Information Center

McHale, John; Cordell, Magda

We are now at a stage in human global development in which the continuous review and assessment of the long-range future implications of our past and present actions becomes crucially important for the survival of human society. This report includes a synoptic view of world trends and alternative futures. The first and major portion of the…

Natural and social factors influencing forest fire occurrence at a local spatial scale

Treesearch

Maria Luisa Chas-Amil; Julia M. Touza; Jeffrey P. Prestemon; Colin J. McClean

2012-01-01

Development of efficient forest fire policies requires an understanding of the underlying reasons behind forest fire ignitions. Globally, there is a close relationship between forest fires and human activities, i.e., fires understood as human events due to negligence (e.g., agricultural burning escapes), and deliberate actions (e.g., pyromania, revenge, land use change...

Marshall Space Flight Center Research and Technology Report 2016

NASA Technical Reports Server (NTRS)

Tinker, M. L.; Abney, M. B. (Compiler); Reynolds, D. W. (Compiler); Morris, H. C. (Compiler)

2017-01-01

Marshall Space Flight Center is essential to human space exploration and our work is a catalyst for ongoing technological development. As we address the challenges facing human deep space exploration, we advance new technologies and applications here on Earth, expand scientific knowledge and discovery, create new economic opportunities, and continue to lead global space exploration.

Time to go global: a consultation on global health competencies for postgraduate doctors

PubMed Central

Walpole, Sarah C.; Shortall, Clare; van Schalkwyk, May CI; Merriel, Abi; Ellis, Jayne; Obolensky, Lucy; Casanova Dias, Marisa; Watson, Jessica; Brown, Colin S.; Hall, Jennifer; Pettigrew, Luisa M.; Allen, Steve

2016-01-01

Background Globalisation is having profound impacts on health and healthcare. We solicited the views of a wide range of stakeholders in order to develop core global health competencies for postgraduate doctors. Methods Published literature and existing curricula informed writing of seven global health competencies for consultation. A modified policy Delphi involved an online survey and face-to-face and telephone interviews over three rounds. Results Over 250 stakeholders participated, including doctors, other health professionals, policymakers and members of the public from all continents of the world. Participants indicated that global health competence is essential for postgraduate doctors and other health professionals. Concerns were expressed about overburdening curricula and identifying what is ‘essential’ for whom. Conflicting perspectives emerged about the importance and relevance of different global health topics. Five core competencies were developed: (1) diversity, human rights and ethics; (2) environmental, social and economic determinants of health; (3) global epidemiology; (4) global health governance; and (5) health systems and health professionals. Conclusions Global health can bring important perspectives to postgraduate curricula, enhancing the ability of doctors to provide quality care. These global health competencies require tailoring to meet different trainees' needs and facilitate their incorporation into curricula. Healthcare and global health are ever-changing; therefore, the competencies will need to be regularly reviewed and updated. PMID:27241136

Fascioliasis: An Ongoing Zoonotic Trematode Infection

PubMed Central

Nyindo, Mramba; Lukambagire, Abdul-Hamid

2015-01-01

Zoonotic trematode infections are an area of the neglected tropical diseases that have become of major interest to global and public health due to their associated morbidity. Human fascioliasis is a trematode zoonosis of interest in public health. It affects approximately 50 million people worldwide and over 180 million are at risk of infection in both developed and underdeveloped countries. The one health paradigm is an area that seeks to address the problem of zoonotic infections through a comprehensive and sustainable approach. This review attempts to address the major challenges in managing human and animal fascioliasis with valuable insights gained from the one health paradigm to global health and multidisciplinary integration. PMID:26417603

Fascioliasis: An Ongoing Zoonotic Trematode Infection.

PubMed

Nyindo, Mramba; Lukambagire, Abdul-Hamid

2015-01-01

Zoonotic trematode infections are an area of the neglected tropical diseases that have become of major interest to global and public health due to their associated morbidity. Human fascioliasis is a trematode zoonosis of interest in public health. It affects approximately 50 million people worldwide and over 180 million are at risk of infection in both developed and underdeveloped countries. The one health paradigm is an area that seeks to address the problem of zoonotic infections through a comprehensive and sustainable approach. This review attempts to address the major challenges in managing human and animal fascioliasis with valuable insights gained from the one health paradigm to global health and multidisciplinary integration.

Global Soil and Sediment transfer during the Anthropocene

NASA Astrophysics Data System (ADS)

Hoffmann, Thomas; Vanacker, Veerle; Stinchcombe, Gary; Penny, Dan; Xixi, Lu

2016-04-01

The vulnerability of soils to human-induced erosion and its downstream effects on fluvial and deltaic ecosystems is highly variable in space and time; dependent on climate, geology, the nature and duration of land use, and topography. Despite our knowledge of the mechanistic relationships between erosion, sediment storage, land-use and climate change, the global patterns of soil erosion, fluvial sediment flux and storage throughout the Holocene remain poorly understood. The newly launched PAGES working group GloSS aims to determine the sensitivity of soil resources and sediment routing systems to varying land use types during the period of agriculture, under contrasting climate regimes and socio-ecological settings. Successfully addressing these questions in relation to the sustainable use of soils, sediments and river systems requires an understanding of past human-landscape interactions. GloSS, therefore, aims to: Develop proxies for, or indices of, human impact on rates of soil erosion and fluvial sediment transfer that are applicable on a global scale and throughout the Holocene; Create a global database of long-term (102-104 years) human-accelerated soil erosion and sediment flux records; Identify hot spots of soil erosion and sediment deposition during the Anthropocene, and Locate data-poor regions where particular socio-ecological systems are not well understood, as strategic foci for future work. This paper will present the latest progress of the PAGES GloSS working group.

[Psychiatry at the turn of the 20th and 21st centuries].

PubMed

Bilikiewicz, A

1998-01-01

The author makes an attempt at considering the most important achievements in psychiatry which have taken place in the global scale during the passing century, and the direction taken up by the development of global psychiatry in the coming century. The 20th century was characterised not only by the impressive development of science, thanks to which completely new possibilities opened up for global psychiatry, but also by the presence of extreme events that took place as a result of false ideologies such as fascism and communism. In the 20th century concepts like homicide, holocaust, the extermination of the mentally ill, experiments on people that are prohibited by the ethics of medicine and the elementary rules of humanity, etc. The paper includes the achievements of diagnosis and therapy of psychiatric disorders and the latest organisational solutions as well as the perspectives for further development of psychiatry. The author also implies the aims that psychiatry has to take up due to the numerous threats from our civilization: the technical-technological development, pollution of the natural environment, the negative changes in human values, the rising brutality in interhuman relations due to racial, national and religious conflicts and terrorism, the disappearing feeling of being safe in society, vision of hunger and poverty in many countries on a few continents, the danger of an epidemic outbreak of new unknown diseases caused by viral mutations, or genetics--the possible negative effects of genetic engineering (cloning of humans), etc. The author tries to define the role of psychiatry in preventing the threats of civilization.

Tackling the threat of antimicrobial resistance: from policy to sustainable action

PubMed Central

Shallcross, Laura J.; Howard, Simon J.; Fowler, Tom; Davies, Sally C.

2015-01-01

Antibiotics underpin all of modern medicine, from routine major surgery through to caesarean sections and modern cancer therapies. These drugs have revolutionized how we practice medicine, but we are in a constant evolutionary battle to evade microbial resistance and this has become a major global public health problem. We have overused and misused these essential medicines both in the human and animal health sectors and this threatens the effectiveness of antimicrobials for future generations. We can only address the threat of antimicrobial resistance (AMR) through international collaboration across human and animal health sectors integrating social, economic and behavioural factors. Our global organizations are rising to the challenge with the recent World Health Assembly resolution on AMR and development of the Global Action plan but we must act now to avoid a return to a pre-antibiotic era. PMID:25918440

Lifelong Education. II. Factors Contributing to Change in Education Systems

ERIC Educational Resources Information Center

Educational Documentation and Information, 1972

1972-01-01

The factors contributing to the need for educational change in the direction of lifelong learning are discussed: global phenomena (economic change and demographic trends); scientific and technological developments (obsolescence of knowledge, development of human sciences, the application of technological progress to education); and social dynamics…

A global, multi-disciplinary, multi-sectorial initiative to combat leptospirosis: Global Leptospirosis Environmental Action Network (GLEAN).

PubMed

Durski, Kara N; Jancloes, Michel; Chowdhary, Tej; Bertherat, Eric

2014-06-05

Leptospirosis has emerged as a major public health problem in both animals and humans. The true burden of this epidemic and endemic disease is likely to be grossly under-estimated due to the non-specific clinical presentations of the disease and the difficulty of laboratory confirmation. The complexity that surrounds the transmission dynamics, particularly in epidemic situations, requires a coordinated, multi-disciplinary effort. Therefore, the Global Leptospirosis Environmental Action Network (GLEAN) was developed to improve global and local strategies of how to predict, prevent, detect, and intervene in leptospirosis outbreaks in order to prevent and control leptospirosis in high-risk populations.

A Global, Multi-Disciplinary, Multi-Sectorial Initiative to Combat Leptospirosis: Global Leptospirosis Environmental Action Network (GLEAN)

PubMed Central

Durski, Kara N.; Jancloes, Michel; Chowdhary, Tej; Bertherat, Eric

2014-01-01

Leptospirosis has emerged as a major public health problem in both animals and humans. The true burden of this epidemic and endemic disease is likely to be grossly under-estimated due to the non-specific clinical presentations of the disease and the difficulty of laboratory confirmation. The complexity that surrounds the transmission dynamics, particularly in epidemic situations, requires a coordinated, multi-disciplinary effort. Therefore, the Global Leptospirosis Environmental Action Network (GLEAN) was developed to improve global and local strategies of how to predict, prevent, detect, and intervene in leptospirosis outbreaks in order to prevent and control leptospirosis in high-risk populations. PMID:24905245

CURRENT PERSPECTIVES OF POTTER'S GLOBAL BIOETHICS AS A BRIDGE BETWEEN CLINICAL (PERSONALIZED) AND PUBLIC HEALTH ETHICS.

PubMed

Turina, Iva Sorta-Bilajac; Brkljacić, Morana; Grgas-Bile, Cecilija; Gajski, Domagoj; Racz, Aleksandar; Cengić, Tomislav

2015-12-01

In the context of modern scientific and technological developments in biomedicine and health care, and the potential consequences of their application on humans and the environment, Potter's global bioethics concept resurfaces. By actualizing Potter's original thoughts on individual bioethical issues, the universality of two of his books, which today represent the backbone of the world bioethical literature, "Bioethics--Bridge to the Future" and "Global Bioethics: Building on the Leopold Legacy", is emphasized. Potter's global bioethics today can legitimately be viewed as a bridge between clinical personalized ethics on the one hand and ethics of public health on the other.

Aedes aegypti Global Suitability Maps Using a Water Container Energy Balance Model for Dengue Risk Applications

NASA Astrophysics Data System (ADS)

Steinhoff, D.

2015-12-01

Dengue infections are estimated to total nearly 400 million per year worldwide, with both the geographic range and the magnitude of infections having increased in the past 50 years. The primary dengue vector mosquito Aedes aegypti is closely associated with humans. It lives exclusively in urban and semi-urban areas, preferentially bites humans, and spends its developmental stages in artificial water containers. Climate regulates the development of Ae. aegypti immature mosquitoes in artificial containers. Potential containers for Ae. aegypti immature development include, but are not limited to, small sundry items (e.g., bottles, cans, plastic containers), buckets, tires, barrels, tanks, and cisterns. Successful development of immature mosquitoes from eggs to larvae, pupae, and eventually adults is largely dependent on the availability of water and the thermal properties of the water in the containers. Recent work has shown that physics-based approaches toward modeling container water properties are promising for resolving the complexities of container water dynamics and the effects on immature mosquito development. An energy balance container model developed by the author, termed the Water Height And Temperature in Container Habitats Energy Model (WHATCH'EM), solves for water temperature and height for user-specified containers with readily available weather data. Here we use WHATCH'EM with NASA Earth Science products used as input to construct global suitability maps based on established water temperature ranges for immature Ae. aegypti mosquitoes. A proxy for dengue risk is provided from habitat suitability, but also population estimates, as Ae. aegypti is closely associated with human activity. NASA gridded Global Population of the World data is used to mask out rural areas with low dengue risk. Suitability maps are illustrated for a variety of containers (size, material, color) and shading scenarios.

Climate change, livelihoods and the multiple determinants of water adequacy: two approaches at regional to global scale

NASA Astrophysics Data System (ADS)

Lissner, Tabea; Reusser, Dominik

2015-04-01

Inadequate access to water is already a problem in many regions of the world and processes of global change are expected to further exacerbate the situation. Many aspects determine the adequacy of water resources: beside actual physical water stress, where the resource itself is limited, economic and social water stress can be experienced if access to resource is limited by inadequate infrastructure, political or financial constraints. To assess the adequacy of water availability for human use, integrated approaches are needed that allow to view the multiple determinants in conjunction and provide sound results as a basis for informed decisions. This contribution proposes two parts of an integrated approach to look at the multiple dimensions of water scarcity at regional to global scale. These were developed in a joint project with the German Development Agency (GIZ). It first outlines the AHEAD approach to measure Adequate Human livelihood conditions for wEll-being And Development, implemented at global scale and at national resolution. This first approach allows viewing impacts of climate change, e.g. changes in water availability, within the wider context of AHEAD conditions. A specific focus lies on the uncertainties in projections of climate change and future water availability. As adequate water access is not determined by water availability alone, in a second step we develop an approach to assess the water requirements for different sectors in more detail, including aspects of quantity, quality as well as access, in an integrated way. This more detailed approach is exemplified at region-scale in Indonesia and South Africa. Our results show that in many regions of the world, water scarcity is a limitation to AHEAD conditions in many countries, regardless of differing modelling output. The more detailed assessments highlight the relevance of additional aspects to assess the adequacy of water for human use, showing that in many regions, quality and infrastructure are the main limitations to water security.

All is not loss: plant biodiversity in the anthropocene.

PubMed

Ellis, Erle C; Antill, Erica C; Kreft, Holger

2012-01-01

Anthropogenic global changes in biodiversity are generally portrayed in terms of massive native species losses or invasions caused by recent human disturbance. Yet these biodiversity changes and others caused directly by human populations and their use of land tend to co-occur as long-term biodiversity change processes in the Anthropocene. Here we explore contemporary anthropogenic global patterns in vascular plant species richness at regional landscape scales by combining spatially explicit models and estimates for native species loss together with gains in exotics caused by species invasions and the introduction of agricultural domesticates and ornamental exotic plants. The patterns thus derived confirm that while native losses are likely significant across at least half of Earth's ice-free land, model predictions indicate that plant species richness has increased overall in most regional landscapes, mostly because species invasions tend to exceed native losses. While global observing systems and models that integrate anthropogenic species loss, introduction and invasion at regional landscape scales remain at an early stage of development, integrating predictions from existing models within a single assessment confirms their vast global extent and significance while revealing novel patterns and their potential drivers. Effective global stewardship of plant biodiversity in the Anthropocene will require integrated frameworks for observing, modeling and forecasting the different forms of anthropogenic biodiversity change processes at regional landscape scales, towards conserving biodiversity within the novel plant communities created and sustained by human systems.

All Is Not Loss: Plant Biodiversity in the Anthropocene

PubMed Central

Ellis, Erle C.; Antill, Erica C.; Kreft, Holger

2012-01-01

Anthropogenic global changes in biodiversity are generally portrayed in terms of massive native species losses or invasions caused by recent human disturbance. Yet these biodiversity changes and others caused directly by human populations and their use of land tend to co-occur as long-term biodiversity change processes in the Anthropocene. Here we explore contemporary anthropogenic global patterns in vascular plant species richness at regional landscape scales by combining spatially explicit models and estimates for native species loss together with gains in exotics caused by species invasions and the introduction of agricultural domesticates and ornamental exotic plants. The patterns thus derived confirm that while native losses are likely significant across at least half of Earth's ice-free land, model predictions indicate that plant species richness has increased overall in most regional landscapes, mostly because species invasions tend to exceed native losses. While global observing systems and models that integrate anthropogenic species loss, introduction and invasion at regional landscape scales remain at an early stage of development, integrating predictions from existing models within a single assessment confirms their vast global extent and significance while revealing novel patterns and their potential drivers. Effective global stewardship of plant biodiversity in the Anthropocene will require integrated frameworks for observing, modeling and forecasting the different forms of anthropogenic biodiversity change processes at regional landscape scales, towards conserving biodiversity within the novel plant communities created and sustained by human systems. PMID:22272360

Europe's Shifting Response to HIV/AIDS: From Human Rights to Risk Management.

PubMed

Smith, Julia

2016-12-01

Despite a history of championing HIV/AIDS as a human rights issue, and a rhetorical commitment to health as a human right, European states and institutions have shifted from a rights-based response to a risk management approach to HIV/AIDS since the economic recession of 2008. An interdisciplinary perspective is applied to analyze health policy changes at the national, regional, and global levels by drawing on data from key informant interviews, and institutional and civil society documents. It is demonstrated that, in the context of austerity measures, member states such as the UK and Greece reduced commitments to rights associated with HIV/AIDS; at the regional level, the EU failed to develop rights-based approaches to address the vulnerabilities and health care needs of key populations affected by HIV/AIDS, particularly migrants and sex workers; and at the global level, the EU backtracked on commitments to global health and is prioritizing the intellectual property rights of pharmaceutical companies over the human rights of people living with HIV/AIDS. The focus within and from the EU is on containment, efficiency, and cost reduction. The rights of those most affected are no longer prioritized.

Initiating a Human Variome Project Country Node.

PubMed

AlAama, Jumana; Smith, Timothy D; Lo, Alan; Howard, Heather; Kline, Alexandria A; Lange, Matthew; Kaput, Jim; Cotton, Richard G H

2011-05-01

Genetic diseases are a pressing global health problem that requires comprehensive access to basic clinical and genetic data to counter. The creation of regional and international databases that can be easily accessed by clinicians and diagnostic labs will greatly improve our ability to accurately diagnose and treat patients with genetic disorders. The Human Variome Project is currently working in conjunction with human genetics societies to achieve this by establishing systems to collect every mutation reported by a diagnostic laboratory, clinic, or research laboratory in a country and store these within a national repository, or HVP Country Node. Nodes have already been initiated in Australia, Belgium, China, Egypt, Malaysia, and Kuwait. Each is examining how to systematically collect and share genetic, clinical, and biochemical information in a country-specific manner that is sensitive to local ethical and cultural issues. This article gathers cases of genetic data collection within countries and takes recommendations from the global community to develop a procedure for countries wishing to establish their own collection system as part of the Human Variome Project. We hope this may lead to standard practices to facilitate global collection of data and allow efficient use in clinical practice, research and therapy. © 2011 Wiley-Liss, Inc.

Potential ramifications of the global economic crisis on human-mediated dispersal of marine non-indigenous species.

PubMed

Floerl, Oliver; Coutts, Ashley

2009-11-01

The global economy is currently experiencing one of its biggest contractions on record. A sharp decline in global imports and exports since 2008 has affected global merchant vessel traffic, the principal mode of bulk commodity transport around the world. During the first quarter of 2009, 10% and 25% of global container and refrigerated vessels, respectively, were reported to be unemployed. A large proportion of these vessels are lying idle at anchor in the coastal waters of South East Asia, sometimes for periods of greater than 3 months. Whilst at anchor, the hulls of such vessels will develop diverse and extensive assemblages of marine biofouling species. Once back in service, these vessels are at risk of transporting higher-than-normal quantities of marine organisms between their respective global trading ports. We discuss the potential ramifications of the global economic crisis on the spread of marine non-indigenous species via global commercial shipping.

Quantifying Biodiversity Losses Due to Human Consumption: A Global-Scale Footprint Analysis.

PubMed

Wilting, Harry C; Schipper, Aafke M; Bakkenes, Michel; Meijer, Johan R; Huijbregts, Mark A J

2017-03-21

It is increasingly recognized that human consumption leads to considerable losses of biodiversity. This study is the first to systematically quantify these losses in relation to land use and greenhouse gas (GHG) emissions associated with the production and consumption of (inter)nationally traded goods and services by presenting consumption-based biodiversity losses, in short biodiversity footprint, for 45 countries and world regions globally. Our results showed that (i) the biodiversity loss per citizen shows large variations among countries, with higher values when per-capita income increases; (ii) the share of biodiversity losses due to GHG emissions in the biodiversity footprint increases with income; (iii) food consumption is the most important driver of biodiversity loss in most of the countries and regions, with a global average of 40%; (iv) more than 50% of the biodiversity loss associated with consumption in developed economies occurs outside their territorial boundaries; and (v) the biodiversity footprint per dollar consumed is lower for wealthier countries. The insights provided by our analysis might support policymakers in developing adequate responses to avert further losses of biodiversity when population and incomes increase. Both the mitigation of GHG emissions and land use related reduction options in production and consumption should be considered in strategies to protect global biodiversity.

What Learning for What Development?

ERIC Educational Resources Information Center

Daniel, John

2014-01-01

After reviewing the evolution of attitudes to poverty and education we note how it influenced the early provision of schooling and the emergence of a global agenda for international development and universal education. At first, this agenda was grounded in the Enlightenment values that inspired the Universal Declaration of Human Rights but…

The science of human security: a response from political science.

PubMed

Roberts, David

2008-01-01

The concept of human security has developed in significance in the last decade to the point that its meaning and validity is hotly contested in the field of international relations, security, and development studies. A key consideration relates to its ambiguity at best and its amorphousness at worst. Medical scholarship proposes approaches that may render more meaningful the concept. However, collaboration and co-operation between political scientists and medical practitioners offers even greater potential to this vital programme. The latter offer the technical and methodological skills and approaches lacking in political science, whilst the former develop political frameworks to shift the causal focus towards human, institutional and structural agency in mass avoidable global civilian mortality.

Changing global essential medicines norms to improve access to AIDS treatment: lessons from Brazil.

PubMed

Nunn, A; Fonseca, E Da; Gruskin, S

2009-01-01

Brazil's large-scale, successful HIV/AIDS treatment programme is considered by many to be a model for other developing countries aiming to improve access to AIDS treatment. Far less is known about Brazil's important role in changing global norms related to international pharmaceutical policy, particularly international human rights, health and trade policies governing access to essential medicines. Prompted by Brazil's interest in preserving its national AIDS treatment policies during World Trade Organisation trade disputes with the USA, these efforts to change global essential medicines norms have had important implications for other countries, particularly those scaling up AIDS treatment. This paper analyses Brazil's contributions to global essential medicines policy and explains the relevance of Brazil's contributions to global health policy today.

An appraisal of China's progress toward the Millennium Development Goals as they relate to children.

PubMed

Strand, Mark A; Fischer, Philip R

2014-08-01

Since their inception in 2000, the Millennium Development Goals (MDGs) have improved understanding of the global development process. Although the goals will not be significantly achieved on a global scale, each country has had accomplishments deserving of attention and analysis. With regard to the MDGs as they relate to children, China has made significant achievements, the deeper understanding of which might help in the process of refreshing the MDGs beyond 2015. China's accomplishments in economic development and human welfare, and the benefits this has brought to its children potentially teach lessons that can be modelled by other countries moving from low- to middle-income status.

Finding "Models" in Clouds

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leung, Ruby

2017-05-01

Internationally recognized Climate Scientist Ruby Leung is a cloud gazer. But rather than looking for shapes, Ruby’s life’s calling is to develop regional atmospheric models to better predict and understand the effects of global climate change at scales relevant to humans and the environment. Ruby’s accomplishments include developing novel methods for modeling mountain clouds and precipitation in climate models, and improving understanding of hydroclimate variability and change. She also has led efforts to develop regional climate modeling capabilities in the Weather Research and Forecasting model that is widely adopted by scientists worldwide. Ruby is part of a team of PNNLmore » researchers studying the impacts of global warming.« less

Attention to Local Health Burden and the Global Disparity of Health Research

PubMed Central

Evans, James A.; Shim, Jae-Mahn; Ioannidis, John P. A.

2014-01-01

Most studies on global health inequality consider unequal health care and socio-economic conditions but neglect inequality in the production of health knowledge relevant to addressing disease burden. We demonstrate this inequality and identify likely causes. Using disability-adjusted life years (DALYs) for 111 prominent medical conditions, assessed globally and nationally by the World Health Organization, we linked DALYs with MEDLINE articles for each condition to assess the influence of DALY-based global disease burden, compared to the global market for treatment, on the production of relevant MEDLINE articles, systematic reviews, clinical trials and research using animal models vs. humans. We then explored how DALYs, wealth, and the production of research within countries correlate with this global pattern. We show that global DALYs for each condition had a small, significant negative relationship with the production of each type of MEDLINE articles for that condition. Local processes of health research appear to be behind this. Clinical trials and animal studies but not systematic reviews produced within countries were strongly guided by local DALYs. More and less developed countries had very different disease profiles and rich countries publish much more than poor countries. Accordingly, conditions common to developed countries garnered more clinical research than those common to less developed countries. Many of the health needs in less developed countries do not attract attention among developed country researchers who produce the vast majority of global health knowledge—including clinical trials—in response to their own local needs. This raises concern about the amount of knowledge relevant to poor populations deficient in their own research infrastructure. We recommend measures to address this critical dimension of global health inequality. PMID:24691431

Attention to local health burden and the global disparity of health research.

PubMed

Evans, James A; Shim, Jae-Mahn; Ioannidis, John P A

2014-01-01

Most studies on global health inequality consider unequal health care and socio-economic conditions but neglect inequality in the production of health knowledge relevant to addressing disease burden. We demonstrate this inequality and identify likely causes. Using disability-adjusted life years (DALYs) for 111 prominent medical conditions, assessed globally and nationally by the World Health Organization, we linked DALYs with MEDLINE articles for each condition to assess the influence of DALY-based global disease burden, compared to the global market for treatment, on the production of relevant MEDLINE articles, systematic reviews, clinical trials and research using animal models vs. humans. We then explored how DALYs, wealth, and the production of research within countries correlate with this global pattern. We show that global DALYs for each condition had a small, significant negative relationship with the production of each type of MEDLINE articles for that condition. Local processes of health research appear to be behind this. Clinical trials and animal studies but not systematic reviews produced within countries were strongly guided by local DALYs. More and less developed countries had very different disease profiles and rich countries publish much more than poor countries. Accordingly, conditions common to developed countries garnered more clinical research than those common to less developed countries. Many of the health needs in less developed countries do not attract attention among developed country researchers who produce the vast majority of global health knowledge--including clinical trials--in response to their own local needs. This raises concern about the amount of knowledge relevant to poor populations deficient in their own research infrastructure. We recommend measures to address this critical dimension of global health inequality.

Sustainable Development. Teacher's Guide to World Resources. Comprehensive Coursework on the Global Environment.

ERIC Educational Resources Information Center

Snyder, Sarah A.

This teacher's guide presents teaching suggestions and presentation materials about sustainable development, important trends that could lead to human and environmental disasters in the future if they continue unchecked, and how each country has a different path to sustainable development. The lesson is divided into six parts and may be completed…

Developing Cross-Cultural Awareness through Foreign Immersion Programs: Implications of University Study Abroad Research for Global Competency Development

ERIC Educational Resources Information Center

Lokkesmoe, Karen J.; Kuchinke, K. Peter; Ardichvili, Alexandre

2016-01-01

Purpose: The purpose of this paper is to investigate the efficacy of foreign immersion programs in terms of increasing cross-cultural awareness among university students in business, accounting, human resources and agriculture. The authors extrapolate from their population to the practice of developing business professionals on international…

The Nature, Challenges and Consequences of Urban Youth Unemployment: A Case of Nairobi City, Kenya

ERIC Educational Resources Information Center

Muiya, Bernard Munyao

2014-01-01

Globally, decline in employment has affected the youth more compared to other cohorts with youth in developing countries being particularly hard hit. There have been various interventions by the Kenyan government to address the challenge of youth employment through human capital development like the Youth Enterprise Development Fund (YEFD).…

From forest to farmland and moraine to meadow: Integrated modeling of Holocene land cover change

NASA Astrophysics Data System (ADS)

Kaplan, J. O.

2012-12-01

Did humans affect global climate over the before the Industrial Era? While this question is hotly debated, the co-evolution of humans and the natural environment over the last 11,700 years had an undisputed role in influencing the development and present state of terrestrial ecosystems, many of which are highly valued today as economic, cultural, and ecological resources. Yet we still have a very incomplete picture of human-environment interactions over the Holocene, both spatially and temporally. In order to address this problem, we combined a global dynamic vegetation model with a new model of preindustrial anthropogenic land cover change. We drive these integrated models with paleoclimate from GCM scenarios, a new synthesis of global demographic, technological, and economic development over preindustrial time, and a global database of historical urbanization covering the last 8000 years. We simulate land cover and land use change, fire, soil erosion, and emissions of CO2 and methane (CH4) from 11,700 years before present to AD 1850. We evaluate our simulations in part with a new set of continental-scale reconstructions of land cover based on records from the Global Pollen Database. Our model results show that climate and tectonic change controlled global land cover in the early Holocene, e.g., shifts in forest biomes in northern continents show an expansion of temperate tree types far to the north of their present day limits, but that by the early Iron Age (1000 BC), humans in Europe, east Asia, and Mesoamerica had a larger influence than natural processes on the landscape. 3000 years before present, anthropogenic deforestation was widespread with most areas of temperate Europe and southwest Asia, east-central China, northern India, and Mesoamerica occupied by a matrix of natural vegetation, cropland and pastures. Burned area and emissions of CO2 and CH4 from wildfires declined slowly over the entire Holocene, as landscape fragmentation and changing agricultural practices led to decreases in burned area. In contrast, soil erosion increased with increasing human pressure over the last 11 ka, except in areas where topsoils became exhausted, e.g., in the Andes and the eastern and southern Mediterranean. While we simulate fluctuations in human impact on the landscape, including periods of widespread land abandonment, e.g., during the Migration Period in Europe that following the end of the Western Roman Empire, approaching the Industrial Revolution nearly all of the landmasses of Europe and south and East Asia are dominated by anthropogenic activities. In contrast, the collapse of the aboriginal populations of the Americas following 15th century European contact leads to a period of ecosystem recovery. Our results highlight the importance of the long histories of both climate change and human demographic, economic, and technological history on the development of continental-scale landscapes. We emphasize the need for improved datasets that use archaeological data synthesis and build on recent theory of preindustrial economic and technological change. A large source of uncertainty in our results comes from assumptions we make about the rates and timing of technologically driven intensification of land use, and the importance of international trade for the subsistence of preindustrial societies.

One Health contributions towards more effective and equitable approaches to health in low- and middle-income countries

PubMed Central

Sharp, J.; Abela-Ridder, B.; Allan, K. J.; Buza, J.; Crump, J. A.; Davis, A.; Del Rio Vilas, V. J.; de Glanville, W. A.; Kazwala, R. R.; Kibona, T.; Lankester, F. J.; Lugelo, A.; Mmbaga, B. T.; Rubach, M. P.; Swai, E. S.; Waldman, L.; Haydon, D. T.; Hampson, K.

2017-01-01

Emerging zoonoses with pandemic potential are a stated priority for the global health security agenda, but endemic zoonoses also have a major societal impact in low-resource settings. Although many endemic zoonoses can be treated, timely diagnosis and appropriate clinical management of human cases is often challenging. Preventive ‘One Health’ interventions, e.g. interventions in animal populations that generate human health benefits, may provide a useful approach to overcoming some of these challenges. Effective strategies, such as animal vaccination, already exist for the prevention, control and elimination of many endemic zoonoses, including rabies, and several livestock zoonoses (e.g. brucellosis, leptospirosis, Q fever) that are important causes of human febrile illness and livestock productivity losses in low- and middle-income countries. We make the case that, for these diseases, One Health interventions have the potential to be more effective and generate more equitable benefits for human health and livelihoods, particularly in rural areas, than approaches that rely exclusively on treatment of human cases. We hypothesize that applying One Health interventions to tackle these health challenges will help to build trust, community engagement and cross-sectoral collaboration, which will in turn strengthen the capacity of fragile health systems to respond to the threat of emerging zoonoses and other future health challenges. One Health interventions thus have the potential to align the ongoing needs of disadvantaged communities with the concerns of the broader global community, providing a pragmatic and equitable approach to meeting the global goals for sustainable development and supporting the global health security agenda. This article is part of the themed issue ‘One Health for a changing world: zoonoses, ecosystems and human well-being’. PMID:28584176

Human Resources for Health Challenges in Nigeria and Nurse Migration.

PubMed

Salami, Bukola; Dada, Foluke O; Adelakun, Folake E

2016-05-01

The emigration of sub-Saharan African health professionals to developed Western nations is an aspect of increasing global mobility. This article focuses on the human resources for health challenges in Nigeria and the emigration of nurses from Nigeria as the country faces mounting human resources for health challenges. Human resources for health issues in Nigeria contribute to poor population health in the country, alongside threats from terrorism, infectious disease outbreaks, and political corruption. Health inequities within Nigeria mirror the geographical disparities in human resources for health distribution and are worsened by the emigration of Nigerian nurses to developed countries such as the United States and the United Kingdom. Nigerian nurses are motivated to emigrate to work in healthier work environments, improve their economic prospects, and advance their careers. Like other migrant African nurses, they experience barriers to integration, including racism and discrimination, in receiving countries. We explore the factors and processes that shape this migration. Given the forces of globalization, source countries and destination countries must implement policies to more responsibly manage migration of nurses. This can be done by implementing measures to retain nurses, promote the return migration of expatriate nurses, and ensure the integration of migrant nurses upon arrival in destination countries. © The Author(s) 2016.

What Are You Going to Do with a Degree in that?: Arguing for the Humanities in an Era of Efficiency

ERIC Educational Resources Information Center

Kent, Eliza F.

2012-01-01

In an era in which the imperatives of global economic competition prompt institutions of higher education to promote vocational practicality and efficiency over all else, advocates of the humanities have struggled to articulate the distinctive value and contribution of our disciplines. This article seeks to develop an argument directed not at…

Hands-On! Living in the Biosphere: Production, Pattern, Population, and Diversity. Developing Active Learning Module on the Human Dimensions of Global Change.

ERIC Educational Resources Information Center

Brown, Dwight

Biogeography examines questions of organism inventory and pattern, organisms' interactions with the environment, and the processes that create and change inventory, pattern, and interactions. This learning module uses time series maps and simple simulation models to illustrate how human actions alter biological productivity patterns at local and…

National HIV/AIDS mortality, prevalence, and incidence rates are associated with the Human Development Index.

PubMed

Lou, Li-Xia; Chen, Yi; Yu, Chao-Hui; Li, You-Ming; Ye, Juan

2014-10-01

HIV/AIDS is a worldwide threat to human health with mortality, prevalence, and incidence rates varying widely. We evaluated the association between the global HIV/AIDS epidemic and national socioeconomic development. We obtained global age-standardized HIV/AIDS mortality, prevalence, and incidence rates from World Health Statistics Report of the World Health Organization. The human development indexes (HDIs) of 141 countries were obtained from a Human Development Report. Countries were divided into 4 groups according to the HDI distribution. We explored the association between HIV/AIDS epidemic and HDI information using Spearman correlation analysis, regression analysis, and the Kruskal-Wallis test. HIV/AIDS mortality, prevalence, and incidence rates were inversely correlated with national HDI (r = -0.675, -0.519, and -0.398, respectively; P < .001), as well as the 4 indicators of HDI (ie, life expectancy at birth, mean years of schooling, expected years of schooling, and gross national income per capita). Low HDI countries had higher HIV/AIDS mortality, prevalence, and incidence rates than that of medium, high, and very high HDI countries. Quantile regression results indicated that HDI had a greater negative effect on the HIV/AIDS epidemic in countries with more severe HIV/AIDS epidemic. Less-developed countries are likely to have more severe HIV/AIDS epidemic. There is a need to pay more attention to HIV/AIDS control in less-developed countries, where lower socioeconomic status might have accelerated the HIV/AIDS epidemic more rapidly. Copyright © 2014 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

Infectious diseases and global warming: Tracking disease incidence rates globally

DOE Office of Scientific and Technical Information (OSTI.GOV)

Low, N.C.

1995-09-01

Given the increasing importance of impact of global warming on public health, there is no global database system to monitor infectious disease and disease in general, and to which global data of climate change and environmental factors, such as temperature, greenhouse gases, and human activities, e.g., coastal development, deforestation, can be calibrated, investigated and correlated. The author proposes the diseases incidence rates be adopted as the basic global measure of morbidity of infectious diseases. The importance of a correctly chosen measure of morbidity of disease is presented. The importance of choosing disease incidence rates as the measure of morbidity andmore » the mathematical foundation of which are discussed. The author further proposes the establishment of a global database system to track the incidence rates of infectious diseases. Only such a global system can be used to calibrate and correlate other globally tracked climatic, greenhouse gases and environmental data. The infrastructure and data sources for building such a global database is discussed.« less

Human impacts and changes in the coastal waters of south China.

PubMed

Wang, Linlin; Li, Qiang; Bi, Hongsheng; Mao, Xian-Zhong

2016-08-15

Human impact on the environment remains at the center of the debate on global environmental change. Using the Hong Kong-Shenzhen corridor in south China as an example, we present evidence that rapid urbanization and economic development in coastal areas were the dominant factors causing rapid changes in coastal waters. From 1990 to 2012, coastal seawater temperature increased ~0.060°C per year, sea level rose 4.4mm per year and pH decreased from 8.2 to 7.7, much faster than global averages. In the same period, there were exponential increases in the local population, gross domestic product and land fill area. Empirical analyses suggest that the large increase in the population affected local temperature, and economic development had a major impact on local pH. Results also show that pH and temperature were significantly correlated with local sea level rise, but pH had more predictive power, suggesting it could be considered a predictor for changes in local sea level. We conclude that human activities could significantly exacerbate local environmental changes which should be considered in predictive models and future development plans in coastal areas. Copyright © 2016 Elsevier B.V. All rights reserved.

NASA Human Spaceflight Architecture Team Lunar Destination Activities

NASA Technical Reports Server (NTRS)

Connolly, J. F.; Mueller, R. P.; Whitley, R. J.

2012-01-01

NASA's Human Spaceflight Architecture Team (HAT) Lunar Destination Team has been developing a number of "Design Reference Missions" (DRM) to inform exploration architecture development, transportation approaches, and destination elements and operations. There are four destinations being considered in the HAT studies: Cis-Lunar, Lunar, Near Earth Asteroids and Mars. The lunar destination includes all activities that occur on the moon itself, but not low lunar orbit operations or Earth Moon LaGrange points which are the responsibility of the HAT Cis-Lunar Team. This paper will review the various surface DRMs developed as representative scenarios that could occur in a human lunar return. The approaches have been divided into two broad categories: a seven day short stay mission with global capabilities and a longer extended duration stay of 28 days which is limited to the lunar poles as a landing zone. The surface elements, trade studies, traverses, concept of operations and other relevant issues and methodologies will be presented and discussed in the context and framework of the HAT ground rules and assumptions which are constrained by NASA's available transportation systems. An international collaborative effort based on the 2011 Global Exploration Roadmap (GER) will also be examined and evaluated.

Strengthening International Collaboration: Geosciences Research and Education in Developing Countries

NASA Astrophysics Data System (ADS)

Fucugauchi, J. U.

2009-05-01

Geophysical research increasingly requires global multidisciplinary approaches and global integration. Global warming, increasing CO2 levels and increased needs of mineral and energy resources emphasize impact of human activities. The planetary view of our Earth as a deeply complex interconnected system also emphasizes the need of international scientific cooperation. International collaboration presents an immense potential and is urgently needed for further development of geosciences research and education. In analyzing international collaboration a relevant aspect is the role of scientific societies. Societies organize meetings, publish journals and books and promote cooperation through academic exchange activities and can further assist communities in developing countries providing and facilitating access to scientific literature, attendance to international meetings, short and long-term stays and student and young researcher mobility. Developing countries present additional challenges resulting from limited economic resources and social and political problems. Most countries urgently require improved educational and research programs. Needed are in-depth analyses of infrastructure and human resources and identification of major problems and needs. Questions may include what are the major limitations and needs in research and postgraduate education in developing countries? what and how should international collaboration do? and what are the roles of individuals, academic institutions, funding agencies, scientific societies? Here we attempt to examine some of these questions with reference to case examples and AGU role. We focus on current situation, size and characteristics of research community, education programs, facilities, economic support, and then move to perspectives for potential development in an international context.

A global, 30-m resolution land-surface water body dataset for 2000

NASA Astrophysics Data System (ADS)

Feng, M.; Sexton, J. O.; Huang, C.; Song, D. X.; Song, X. P.; Channan, S.; Townshend, J. R.

2014-12-01

Inland surface water is essential to terrestrial ecosystems and human civilization. The distribution of surface water in space and its change over time are related to many agricultural, environmental and ecological issues, and are important factors that must be considered in human socioeconomic development. Accurate mapping of surface water is essential for both scientific research and policy-driven applications. Satellite-based remote sensing provides snapshots of Earth's surface and can be used as the main input for water mapping, especially in large areas. Global water areas have been mapped with coarse resolution remotely sensed data (e.g., the Moderate Resolution Imaging Spectroradiometer (MODIS)). However, most inland rivers and water bodies, as well as their changes, are too small to map at such coarse resolutions. Landsat TM (Thematic Mapper) and ETM+ (Enhanced Thematic Mapper Plus) imagery has a 30m spatial resolution and provides decades of records (~40 years). Since 2008, the opening of the Landsat archive, coupled with relatively lower costs associated with computing and data storage, has made comprehensive study of the dynamic changes of surface water over large even global areas more feasible. Although Landsat images have been used for regional and even global water mapping, the method can hardly be automated due to the difficulties on distinguishing inland surface water with variant degrees of impurities and mixing of soil background with only Landsat data. The spectral similarities to other land cover types, e.g., shadow and glacier remnants, also cause misidentification. We have developed a probabilistic based automatic approach for mapping inland surface water bodies. Landsat surface reflectance in multiple bands, derived water indices, and data from other sources are integrated to maximize the ability of identifying water without human interference. The approach has been implemented with open-source libraries to facilitate processing large amounts of Landsat images on high-performance computing machines. It has been applied to the ~9,000 Landsat scenes of the Global Land Survey (GLS) 2000 data collection to produce a global, 30m resolution inland surface water body data set, which will be made available on the Global Land Cover Facility (GLCF) website (http://www.landcover.org).

Understanding Global Change: Frameworks and Models for Teaching Systems Thinking

NASA Astrophysics Data System (ADS)

Bean, J. R.; Mitchell, K.; Zoehfeld, K.; Oshry, A.; Menicucci, A. J.; White, L. D.; Marshall, C. R.

2017-12-01

The scientific and education communities must impart to teachers, students, and the public an understanding of how the various factors that drive climate and global change operate, and why the rates and magnitudes of these changes related to human perturbation of Earth system processes today are cause for deep concern. Even though effective educational modules explaining components of the Earth and climate system exist, interdisciplinary learning tools are necessary to conceptually link the causes and consequences of global changes. To address this issue, the Understanding Global Change Project at the University of California Museum of Paleontology (UCMP) at UC Berkeley developed an interdisciplinary framework that organizes global change topics into three categories: (1) causes of climate change, both human and non-human (e.g., burning of fossil fuels, deforestation, Earth's tilt and orbit), (2) Earth system processes that shape the way the Earth works (e.g., Earth's energy budget, water cycle), and (3) the measurable changes in the Earth system (e.g., temperature, precipitation, ocean acidification). To facilitate student learning about the Earth as a dynamic, interacting system, a website will provide visualizations of Earth system models and written descriptions of how each framework topic is conceptually linked to other components of the framework. These visualizations and textual summarizations of relationships and feedbacks in the Earth system are a unique and crucial contribution to science communication and education, informed by a team of interdisciplinary scientists and educators. The system models are also mechanisms by which scientists can communicate how their own work informs our understanding of the Earth system. Educators can provide context and relevancy for authentic datasets and concurrently can assess student understanding of the interconnectedness of global change phenomena. The UGC resources will be available through a web-based platform and scalable professional development programming to facilitate systemic changes in the teaching and learning about climate and global change. We are establishing a diverse community of scientists and educators across the country that are using these tools, and plan to create local networks supported by UGC staff and partners.

Impacts of conservation and human development policy across stakeholders and scales

PubMed Central

Li, Cong; Zheng, Hua; Li, Shuzhuo; Chen, Xiaoshu; Li, Jie; Zeng, Weihong; Liang, Yicheng; Polasky, Stephen; Feldman, Marcus W.; Ruckelshaus, Mary; Ouyang, Zhiyun; Daily, Gretchen C.

2015-01-01

Ideally, both ecosystem service and human development policies should improve human well-being through the conservation of ecosystems that provide valuable services. However, program costs and benefits to multiple stakeholders, and how they change through time, are rarely carefully analyzed. We examine one of China’s new ecosystem service protection and human development policies: the Relocation and Settlement Program of Southern Shaanxi Province (RSP), which pays households who opt voluntarily to resettle from mountainous areas. The RSP aims to reduce disaster risk, restore important ecosystem services, and improve human well-being. We use household surveys and biophysical data in an integrated economic cost–benefit analysis for multiple stakeholders. We project that the RSP will result in positive net benefits to the municipal government, and to cross-region and global beneficiaries over the long run along with environment improvement, including improved water quality, soil erosion control, and carbon sequestration. However, there are significant short-run relocation costs for local residents so that poor households may have difficulty participating because they lack the resources to pay the initial costs of relocation. Greater subsidies and subsequent supports after relocation are necessary to reduce the payback period of resettled households in the long run. Compensation from downstream beneficiaries for improved water and from carbon trades could be channeled into reducing relocation costs for the poor and sharing the burden of RSP implementation. The effectiveness of the RSP could also be greatly strengthened by early investment in developing human capital and environment-friendly jobs and establishing long-term mechanisms for securing program goals. These challenges and potential solutions pervade ecosystem service efforts globally. PMID:26082546

The World Meteorological Organization Focus on Urban Issues

NASA Astrophysics Data System (ADS)

Terblanche, D. E.

2015-12-01

Many of the milestones of human development can be traced back to people assembled in urban settings where economies of scale, competition and social interaction stimulated innovation. Considering that more than half the global pollution now lives in cities and towns and that most of the growth in the global pollution in the remainder of this century will continue to take place in the urban environment, the question could be asked whether humankind will continue to capitalize on the traditional benefits of city life to find solutions for growing environmental challenges? In the past cities developed organically. They evolved through trial and error into livable environments. Things have now changed. The global population is larger, urbanization is rapid, pressure on Earth's limited resources is constraining and we are faced with a changing climate. If cities are now allowed to develop in a haphazard manner, the fight for survival in the city will overshadow its entrepreneurial spirit. It is for this reason that the 11th Sustainable Development Goal will focus on: 'Making cities and human settlements inclusive, safe, resilient and sustainable'. There is now a window of opportunity for weather, climate, water and environmental scientists to contribute towards a more sustainable urban future by ensuring that science based services form an integrated part of urban planning, development and management. WMO recognizes that rapid urbanization will require new types of new and enhanced services. Such integrated urban weather, environment and climate services will assist cities to deal better with hazards such as storm surge, flooding, heat waves, and air pollution episodes, especially in a changing climate. From a research perspective the World Climate Research Programme, the World Weather Research Programme and the Global Atmosphere Watch Programme all have a unique contribution to make in this regard.

Multimodel Uncertainty Changes in Simulated River Flows Induced by Human Impact Parameterizations

NASA Technical Reports Server (NTRS)

Liu, Xingcai; Tang, Qiuhong; Cui, Huijuan; Mu, Mengfei; Gerten Dieter; Gosling, Simon; Masaki, Yoshimitsu; Satoh, Yusuke; Wada, Yoshihide

2017-01-01

Human impacts increasingly affect the global hydrological cycle and indeed dominate hydrological changes in some regions. Hydrologists have sought to identify the human-impact-induced hydrological variations via parameterizing anthropogenic water uses in global hydrological models (GHMs). The consequently increased model complexity is likely to introduce additional uncertainty among GHMs. Here, using four GHMs, between-model uncertainties are quantified in terms of the ratio of signal to noise (SNR) for average river flow during 1971-2000 simulated in two experiments, with representation of human impacts (VARSOC) and without (NOSOC). It is the first quantitative investigation of between-model uncertainty resulted from the inclusion of human impact parameterizations. Results show that the between-model uncertainties in terms of SNRs in the VARSOC annual flow are larger (about 2 for global and varied magnitude for different basins) than those in the NOSOC, which are particularly significant in most areas of Asia and northern areas to the Mediterranean Sea. The SNR differences are mostly negative (-20 to 5, indicating higher uncertainty) for basin-averaged annual flow. The VARSOC high flow shows slightly lower uncertainties than NOSOC simulations, with SNR differences mostly ranging from -20 to 20. The uncertainty differences between the two experiments are significantly related to the fraction of irrigation areas of basins. The large additional uncertainties in VARSOC simulations introduced by the inclusion of parameterizations of human impacts raise the urgent need of GHMs development regarding a better understanding of human impacts. Differences in the parameterizations of irrigation, reservoir regulation and water withdrawals are discussed towards potential directions of improvements for future GHM development. We also discuss the advantages of statistical approaches to reduce the between-model uncertainties, and the importance of calibration of GHMs for not only better performances of historical simulations but also more robust and confidential future projections of hydrological changes under a changing environment.

The Development of an Instrument to Measure Global Dimensions of Maternal Care in Rhesus Macaques (Macaca mulatta)

PubMed Central

McCormack, K.; Howell, B. R.; Guzman, D.; Villongco, C.; Pears, K.; Kim, H.; Gunnar, M.R.; Sanchez, M.M.

2014-01-01

One of the strongest predictors of healthy child development is the quality of maternal care. Although many measures of observation and self-report exist in humans to assess global aspects of maternal care, such qualitative measures are lacking in nonhuman primates. In this study we developed an instrument to measure global aspects of maternal care in rhesus monkeys, with the goal of complementing the individual behavioral data collected using a well-established rhesus macaque ethogram during the first months postpartum. The 22 items of the instrument were adapted from human maternal sensitivity assessments and a maternal Q-sort instrument already published for macaques. The 22 items formed four dimensions with high levels of internal reliability that represented major constructs of maternal care: 1) Sensitivity/Responsivity, 2) Protectiveness, 3) Permissiveness, and 4) Irritability. These dimensions yielded high construct validity when correlated with mother-infant frequency and duration behavior that was collected from focal observations across the first three postnatal months. In addition, comparisons of two groups of mothers (Maltreating versus Competent mothers), showed significant differences across the dimensions suggesting that this instrument has strong concurrent validity, even after controlling for focal observation variables that have been previously shown to significantly differentiate these groups. Our findings suggest that this Instrument of Macaque Maternal Care (IMMC) has the potential to capture global aspects of the mother-infant relationship that complement individual behaviors collected through focal observations. PMID:25066041

The development of an instrument to measure global dimensions of maternal care in rhesus macaques (Macaca mulatta).

PubMed

McCormack, K; Howell, B R; Guzman, D; Villongco, C; Pears, K; Kim, H; Gunnar, M R; Sanchez, M M

2015-01-01

One of the strongest predictors of healthy child development is the quality of maternal care. Although many measures of observation and self-report exist in humans to assess global aspects of maternal care, such qualitative measures are lacking in nonhuman primates. In this study, we developed an instrument to measure global aspects of maternal care in rhesus monkeys, with the goal of complementing the individual behavioral data collected using a well-established rhesus macaque ethogram during the first months postpartum. The 22 items of the instrument were adapted from human maternal sensitivity assessments and a maternal Q-sort instrument already published for macaques. The 22 items formed four dimensions with high levels of internal reliability that represented major constructs of maternal care: (1) Sensitivity/Responsivity, (2) Protectiveness, (3) Permissiveness, and (4) Irritability. These dimensions yielded high construct validity when correlated with mother-infant frequency and duration behavior that was collected from focal observations across the first 3 postnatal months. In addition, comparisons of two groups of mothers (Maltreating vs. Competent mothers) showed significant differences across the dimensions suggesting that this instrument has strong concurrent validity, even after controlling for focal observation variables that have been previously shown to significantly differentiate these groups. Our findings suggest that this Instrument of Macaque Maternal Care has the potential to capture global aspects of the mother-infant relationship that complement individual behaviors collected through focal observations. © 2014 Wiley Periodicals, Inc.

A human-driven decline in global burned area

NASA Astrophysics Data System (ADS)

Andela, N.; Morton, D. C.; Chen, Y.; van der Werf, G.; Giglio, L.; Kasibhatla, P. S.; Randerson, J. T.

2016-12-01

Fire is an important and dynamic ecosystem process that influences many aspects of the global Earth system. Here, we used several different satellite datasets to assess trends in global burned area during 1998 to 2014. Global burned area decreased by about 21.6 ± 8.5% over the period from 1998-2014, with large regional declines observed in savanna and grassland ecosystems in northern Africa, Eurasia, and South America. The decrease in burned area remained robust after removing the influence of climate (16.0 ± 6.0%), implicating human activity as a likely driver. To further investigate the mechanisms contributing to regional and global trends, we conducted several kinds of analysis, including separation of burned area into ignition and fire size components and geospatial analysis of fire trends in relationship with demographic and land use variables. We found that fire number was a more important factor contributing to burned area trends than fire size, suggesting a reduction in the use of fire for management purposes. Concurrent decreases in fire size also contributed to the trend outside of North and South America, suggesting a role for greater landscape fragmentation. From our geospatial analysis, we developed a conceptual model that incorporates a range of drivers for human-driven changes in biomass burning that can be used to guide global fire models, currently unable to reproduce these large scale recent trends. Patterns of agricultural expansion and land use intensification are likely to further contribute to declining burned area trends in future decades, with important consequences for Earth system processes mediated by surface albedo, greenhouse gas emissions, and aerosols. Our results also highlight the vulnerability of savannas and grassland to land use changes with unprecedented global scale consequences for vegetation structure and the carbon cycle.

Projecting global land-use change and its effect on ecosystem service provision and biodiversity with simple models.

PubMed

Nelson, Erik; Sander, Heather; Hawthorne, Peter; Conte, Marc; Ennaanay, Driss; Wolny, Stacie; Manson, Steven; Polasky, Stephen

2010-12-15

As the global human population grows and its consumption patterns change, additional land will be needed for living space and agricultural production. A critical question facing global society is how to meet growing human demands for living space, food, fuel, and other materials while sustaining ecosystem services and biodiversity [1]. We spatially allocate two scenarios of 2000 to 2015 global areal change in urban land and cropland at the grid cell-level and measure the impact of this change on the provision of ecosystem services and biodiversity. The models and techniques used to spatially allocate land-use/land-cover (LULC) change and evaluate its impact on ecosystems are relatively simple and transparent [2]. The difference in the magnitude and pattern of cropland expansion across the two scenarios engenders different tradeoffs among crop production, provision of species habitat, and other important ecosystem services such as biomass carbon storage. For example, in one scenario, 5.2 grams of carbon stored in biomass is released for every additional calorie of crop produced across the globe; under the other scenario this tradeoff rate is 13.7. By comparing scenarios and their impacts we can begin to identify the global pattern of cropland and irrigation development that is significant enough to meet future food needs but has less of an impact on ecosystem service and habitat provision. Urban area and croplands will expand in the future to meet human needs for living space, livelihoods, and food. In order to jointly provide desired levels of urban land, food production, and ecosystem service and species habitat provision the global society will have to become much more strategic in its allocation of intensively managed land uses. Here we illustrate a method for quickly and transparently evaluating the performance of potential global futures.

From forest to farmland and meadow to metropolis: What role for humans in explaining the enigma of Holocene CO2 and methane concentrations?

NASA Astrophysics Data System (ADS)

Kaplan, Jed O.

2013-04-01

Did humans affect global climate over the before the Industrial Era? While this question is hotly debated, the co-evolution of humans and the natural environment over the last 11,700 years had an undisputed role in influencing the development and present state of terrestrial ecosystems, many of which are highly valued today as economic, cultural, and ecological resources. Yet we still have a very incomplete picture of human-environment interactions over the Holocene, both spatially and temporally. In order to address this problem, we combined a global dynamic vegetation model with a new model of preindustrial anthropogenic land cover change. We drive these integrated models with paleoclimate from GCM scenarios, a new synthesis of global demographic, technological, and economic development over preindustrial time, and a global database of historical urbanization covering the last 8000 years. We simulate land cover and land use change, fire, soil erosion, and emissions of CO2 and methane (CH4) from 11,700 years before present to AD 1850. We evaluate our simulations in part with a new set of continental-scale reconstructions of land cover based on records from the Global Pollen Database. Our model results show that climate and tectonic change controlled global land cover in the early Holocene, e.g., shifts in forest biomes in northern continents show an expansion of temperate tree types far to the north of their present day limits, but that by the early Iron Age (1000 BC), humans in Europe, east Asia, and Mesoamerica had a larger influence than natural processes on the landscape. 3000 years before present, anthropogenic deforestation was widespread with most areas of temperate Europe and southwest Asia, east-central China, northern India, and Mesoamerica occupied by a matrix of natural vegetation, cropland and pastures. Burned area and emissions of CO2 and CH4 from wildfires declined slowly over the entire Holocene, as landscape fragmentation and changing agricultural practices led to decreases in burned area. In contrast, soil erosion increased with increasing human pressure over the last 11 ka, except in areas where topsoils became exhausted, e.g., in the Andes and the eastern and southern Mediterranean. While we simulate fluctuations in human impact on the landscape, including periods of widespread land abandonment, e.g., during the Migration Period in Europe that following the end of the Western Roman Empire, approaching the Industrial Revolution nearly all of the landmasses of Europe and south and East Asia are dominated by anthropogenic activities. In contrast, the collapse of the aboriginal populations of the Americas following 15th century European contact leads to a period of ecosystem recovery. Our results highlight the importance of the long histories of both climate change and human demographic, economic, and technological history on the development of continental-scale landscapes. We emphasize the need for improved datasets that use archaeological data synthesis and build on recent theory of preindustrial economic and technological change. A large source of uncertainty in our results comes from assumptions we make about the rates and timing of technologically driven intensification of land use, and the importance of international trade for the subsistence of preindustrial societies.

Global change in the geosphere-biosphere: Initial priorities for an IGBP

NASA Technical Reports Server (NTRS)

1986-01-01

Some of the factors are outlined that leads one to endorse the concept of focused, international geosphere-biosphere program, whose goal is to understand the interactive physical, chemical, and biological processes that regulate the Earth's unique environment for life, the changes that are occurring in this system, and the manner in which they are influenced by human actions. There is a pressing need to assess the consequence of human activities in the context of natural global change and to provide the body of knowledge necessary to chart a wise course to the future. A number of specific objectives were developed which leads to the conclusion that the need for new programs of observation of the Earth as a planet, a better understanding of the interactive processes that governs its changes, the development of a new generation of coupled modes, and the design of suitable tests to guide the development of these models and the understanding of the processes involved. Some general recommendations are summarized.

Mapping the global football field: a sociological model of transnational forces within the world game.

PubMed

Giulianotti, Richard; Robertson, Roland

2012-06-01

This paper provides a sociological model of the key transnational political and economic forces that are shaping the 'global football field'. The model draws upon, and significantly extends, the theory of the 'global field' developed previously by Robertson. The model features four quadrants, each of which contains a dominant operating principle, an 'elemental reference point', and an 'elemental theme'. The quadrants contain, first, neo-liberalism, associated with the individual and elite football clubs; second, neo-mercantilism, associated with nation-states and national football systems; third, international relations, associated with international governing bodies; and fourth, global civil society, associated with diverse institutions that pursue human development and/or social justice. We examine some of the interactions and tensions between the major institutional and ideological forces across the four quadrants. We conclude by examining how the weakest quadrant, featuring global civil society, may gain greater prominence within football. In broad terms, we argue that our four-fold model may be utilized to map and to examine other substantive research fields with reference to globalization. © London School of Economics and Political Science 2012.

Demographic controls of future global fire risk

NASA Astrophysics Data System (ADS)

Knorr, W.; Arneth, A.; Jiang, L.

2016-08-01

Wildfires are an important component of terrestrial ecosystem ecology but also a major natural hazard to societies, and their frequency and spatial distribution must be better understood. At a given location, risk from wildfire is associated with the annual fraction of burned area, which is expected to increase in response to climate warming. Until recently, however, only a few global studies of future fire have considered the effects of other important global environmental change factors such as atmospheric CO2 levels and human activities, and how these influence fires in different regions. Here, we contrast the impact of climate change and increasing atmospheric CO2 content on burned area with that of demographic dynamics, using ensembles of climate simulations combined with historical and projected population changes under different socio-economic development pathways for 1901-2100. Historically, humans notably suppressed wildfires. For future scenarios, global burned area will continue to decline under a moderate emissions scenario, except for low population growth and fast urbanization, but start to increase again from around mid-century under high greenhouse gas emissions. Contrary to common perception, we find that human exposure to wildfires increases in the future mainly owing to projected population growth in areas with frequent wildfires, rather than by a general increase in burned area.

Veterinary public health capacity-building in India: a grim reflection of the developing world's underpreparedness to address zoonotic risks.

PubMed

Kakkar, Manish; Abbas, Syed Shahid; Kumar, Ashok; Hussain, Mohammad Akhtar; Sharma, Kavya; Bhatt, Purvi Mehta; Zodpey, Sanjay

2013-01-01

Veterinary public health (VPH) is ideally suited to promote convergence between human, animal and environmental sectors. Recent zoonotic and emerging infectious disease events have given rise to increasing calls for efforts to build global VPH capacities. However, even with their greater vulnerability to such events, including their economic and livelihood impacts, the response from low-and middle-income countries such as India has been suboptimal, thereby elevating global health risks. Addressing risks effectively at the human-animal interface in these countries will require a clear vision, consistent policies, strategic approach and sustained political commitment to reform and refine the current VPH capacity-building efforts. Only then can the discipline serve its goal of disease prevention, poverty alleviation and support for sustainable livelihoods through improvements in human and animal health.

Population Growth. Understanding Global Change: Earth Science and Human Impacts. Global Change Instruction Program.

ERIC Educational Resources Information Center

Jacobsen, Judith E.

The Global Change Instruction Program was designed by college professors to fill a need for interdisciplinary materials on the emerging science of global change. This instructional module concentrates on interactions between population growth and human activities that produce global change. The materials are designed for undergraduate students…

The role of bioethics in the international prescription drug market: economics and global justice.

PubMed

Newland, Shelby E

2006-01-01

In terms of health care access, bioethics has an important role to inform and shape policy issues and develop interdisciplinary ideas and interventions. The rising price of prescription drugs presents one of the most looming barriers to health care access in the world today. Including both theoretical and practical features of the pharmaceutical industry's behavior is necessary to find ethical solutions towards increasing access. Bioethics can evaluate global justice by weighing human rights theory and future innovation at the macro level, and by addressing market forces and responsibilities at the micro level. Inherent structural features of pharmaceuticals, such as its reliance on research and development, cause the industry to employ pricing strategies that seem counter-intuitive to conventional wisdom, but that result in producing a just allocation as defined by market forces. Parallel trade and drug exportation/reimportation threaten the saliency of the industry's differential pricing scheme; a case-study of a single "Euro-price" within the European Union illustrates how this will actually create harm to the most needy member states. This complex situation requires solutions weighing arguments from human rights theory with those from economic theory to arrive at the most globally just allocation of prescription drugs in the global marketplace, as well as to ensure future innovation and scientific progress. Bioethicists as well as economists need to partake urgently in this discourse for the betterment of the global injustices in the international prescription drug market.

Inter-Philosophies Dialogue: Creating a Paradigm for Global Health Ethics.

PubMed

Benatar, Solomon; Daibes, Ibrahim; Tomsons, Sandra

While debate remains about the definition and goals of work on global health, there is growing agreement that our moral starting point is the reality of unjust inequalities in the distribution of the conditions necessary for human health and well-being. With the growth of multi-jurisdictional and multicultural global health partnerships, the adequacy of the prevailing bioethical paradigm guiding the conduct of global health research and practice is being increasingly challenged. In response to ethical challenges and conflicts confronted by decision-makers in global health research and practice, we propose an innovative methodology that could be developed to bridge the gap between polarized systems of ideas and values (metaphysical, epistemological, moral, and political). Our inter-philosophies methodology provides the potential to construct a new, shared paradigm for global health ethics, thereby increasing the capacity for solidarity and shared decision-making in global health research and practice.

[Food poisoning--importance of international perspective].

PubMed

Nishibuchi, Mitsuaki

2012-08-01

It is important to obtain the information on food security in the countries other than Japan since more than 60 % of the food consumed come from these countries. Food security is now considered as a global issue. A global trend persuading us to provide safe food to humans is based on the concept of human security development associated with a sense of human mission to sustain one's life. Another global tendency pushing us to secure safety and hygiene of food is driven by the economic pressure coming from the rules in international trade established by Codex Committee under FAO/WHO. In contrast to these trends under globalization requesting safe and hygienic food, food habits based on tradition or religion are maintained locally in various parts of the world. These local habits include eating raw or improperly cooked foods, which may become a risk of being exposed to food poisoning pathogens. This issue may be adequately solved by a risk assessment approach based on the concept of appropriate level of protection (ALOP). Like or not, people in some local areas live in the unhygienic environment where they are unintentionally and frequently exposed to enteric pathogens or immunologically cross-reacting microorganisms through which they may acquire specific immunity to the pathogens and escape from infection by the pathogens. There are therefore many areas in the world where people understand the necessity to provide safe food at the international level (globalization) but actually consume food in varying hygienic conditions from area to area due in part to traditional food habits or living environments (localization); we call this situation as glocalization (global+local).

Humans, Evolutionary and Ecologic Forces Shaped the Phylogeography of Recently Emerged Diseases

PubMed Central

Keim, Paul S.; Wagner, David M.

2009-01-01

Many infectious diseases have emerged and circulated around the world with the development of human civilizations and global commerce. Anthrax, plague and tularemia are three such zoonotic diseases that have been intensely studied through genome characterization and phylogeographic analyses. A few highly fit genotypes within each of the causative species represent the vast majority of observed disease cases. Mutational and selective forces working together create highly adapted pathogens, but this has to be coupled with ecological opportunities for global expansion. This Review describes the distributions of the bacteria that cause anthrax, plague and tularemia and investigates the forces that created a clonal structure in both these species, and specific groups within these species. PMID:19820723

Time to go global: a consultation on global health competencies for postgraduate doctors.

PubMed

Walpole, Sarah C; Shortall, Clare; van Schalkwyk, May Ci; Merriel, Abi; Ellis, Jayne; Obolensky, Lucy; Casanova Dias, Marisa; Watson, Jessica; Brown, Colin S; Hall, Jennifer; Pettigrew, Luisa M; Allen, Steve

2016-09-01

Globalisation is having profound impacts on health and healthcare. We solicited the views of a wide range of stakeholders in order to develop core global health competencies for postgraduate doctors. Published literature and existing curricula informed writing of seven global health competencies for consultation. A modified policy Delphi involved an online survey and face-to-face and telephone interviews over three rounds. Over 250 stakeholders participated, including doctors, other health professionals, policymakers and members of the public from all continents of the world. Participants indicated that global health competence is essential for postgraduate doctors and other health professionals. Concerns were expressed about overburdening curricula and identifying what is 'essential' for whom. Conflicting perspectives emerged about the importance and relevance of different global health topics. Five core competencies were developed: (1) diversity, human rights and ethics; (2) environmental, social and economic determinants of health; (3) global epidemiology; (4) global health governance; and (5) health systems and health professionals. Global health can bring important perspectives to postgraduate curricula, enhancing the ability of doctors to provide quality care. These global health competencies require tailoring to meet different trainees' needs and facilitate their incorporation into curricula. Healthcare and global health are ever-changing; therefore, the competencies will need to be regularly reviewed and updated. © The Author 2016. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene.

The Globalization Classroom: New Option for Becoming More Human?

ERIC Educational Resources Information Center

Svetelj, Tony

2014-01-01

Within a multi-cultural and multi-religious society, exposed to the challenges of globalization, a traditional understanding of humanism offers insufficient frameworks for an adequate comprehension of human agency, its flourishing and search for meaning. The process of globalization continuously shakes the pedagogical assumptions and principles of…

Towards mutual trust, transparency and equity in virus sharing mechanism: the avian influenza case of Indonesia.

PubMed

Sedyaningsih, Endang R; Isfandari, Siti; Soendoro, Triono; Supari, Siti Fadilah

2008-06-01

As the country hardest hit by avian influenza, both in poultry and in human, Indonesia's decision to withhold samples of avian influenza virus A (H5N1) has fired up a global controversy. The objective of this paper is to describe the position taken by Indonesia in the events leading to the decision and in those conducted to resolve the situation. The sources for this paper are the Indonesian human influenza A(H5N1) case reports and study results, summaries, minutes and reports of national and international meetings of virus sharing, and other related Indonesian and WHO documents. The International Health Regulations 2005 have been applied in different ways based on different interpretations. While one party insists on the importance of free, non-conditional, virus sharing for risk assessment and risk response, Indonesia--as supported by most of the developing countries--stresses on the more basic principles such as sovereignty of a country over its biological materials, transparency of the global system, and equity between developed and developing nations. This event demonstrates the unresolved imbalance between the affluent high-tech countries and the poor agriculture-based countries. Regional, global and in-country meetings must continue to be conducted to find solutions acceptable to all.

2014 Future Earth Young Scientists Conference on Integrated Science and Knowledge Co-Production for Ecosystems and Human Well-Being †

PubMed Central

Shiue, Ivy; Samberg, Leah; Kulohoma, Benard; Dogaru, Diana; Wyborn, Carina; Hamel, Perrine; Jørgensen, Peter Søgaard; Lussier, Paul; Sundaram, Bharath; Lim, Michelle; Tironi, Antonio

2014-01-01

Effective integration in science and knowledge co-production is a challenge that crosses research boundaries, climate regions, languages and cultures. Early career scientists are crucial in the identification of, and engagement with, obstacles and opportunities in the development of innovative solutions to complex and interconnected problems. On 25–31 May 2014, International Council for Science and International Social Science Council, in collaboration with the International Network of Next-Generation Ecologists and Institute for New Economic Thinking: Young Scholars Initiative, assembled a group of early career researchers with diverse backgrounds and research perspectives to reflect on and debate relevant issues around ecosystems and human wellbeing in the transition towards green economy, funded by the German Research Foundation, at Villa Vigoni, Italy. As a group of young scientists, we have come to a consensus that collaboration and communication among a diverse group of peers from different geographic regions could break down the barriers to multi-disciplinary research designed to solve complex global-scale problems. We also propose to establish a global systematic thinking to monitor global socio-ecological systems and to develop criteria for a “good” anthropocene. Finally, we aim to bridge gaps among research, the media, and education from a governance perspective linking with “sustainable development goals”. PMID:25390795

Water footprint scenarios for 2050: a global analysis.

PubMed

Ercin, A Ertug; Hoekstra, Arjen Y

2014-03-01

This study develops water footprint scenarios for 2050 based on a number of drivers of change: population growth, economic growth, production/trade pattern, consumption pattern (dietary change, bioenergy use) and technological development. The objective the study is to understand the changes in the water footprint (WF) of production and consumption for possible futures by region and to elaborate the main drivers of this change. In addition, we assess virtual water flows between the regions of the world to show dependencies of regions on water resources in other regions under different possible futures. We constructed four scenarios, along two axes, representing two key dimensions of uncertainty: globalization versus regional selfsufficiency, and economy-driven development versus development driven by social and environmental objectives. The study shows how different drivers will change the level of water consumption and pollution globally in 2050. The presented scenarios can form a basis for a further assessment of how humanity can mitigate future freshwater scarcity. We showed with this study that reducing humanity's water footprint to sustainable levels is possible even with increasing populations, provided that consumption patterns change. This study can help to guide corrective policies at both national and international levels, and to set priorities for the years ahead in order to achieve sustainable and equitable use of the world's fresh water resources. Copyright © 2013 Elsevier Ltd. All rights reserved.

Reviewing Biosphere Reserves globally: effective conservation action or bureaucratic label?

PubMed

Coetzer, Kaera L; Witkowski, Edward T F; Erasmus, Barend F N

2014-02-01

The Biosphere Reserve (BR) model of UNESCO's Man and the Biosphere Programme reflects a shift towards more accountable conservation. Biosphere Reserves attempt to reconcile environmental protection with sustainable development; they explicitly acknowledge humans, and human interests in the conservation landscape while still maintaining the ecological values of existing protected areas. Conceptually, this model is attractive, with 610 sites currently designated globally. Yet the practical reality of implementing dual 'conservation' and 'development' goals is challenging, with few examples successfully conforming to the model's full criteria. Here, we review the history of Biosphere Reserves from first inception in 1974 to the current status quo, and examine the suitability of the designation as an effective conservation model. We track the spatial expansion of Biosphere Reserves globally, assessing the influence of the Statutory Framework of the World Network of Biosphere Reserves and Seville strategy in 1995, when the BR concept refocused its core objectives on sustainable development. We use a comprehensive range of case studies to discuss conformity to the Programme, the social and ecological consequences associated with implementation of the designation, and challenges in aligning conservation and development. Given that the 'Biosphere Reserve' label is a relatively unknown designation in the public arena, this review also provides details on popularising the Biosphere Reserve brand, as well as prospects for further research, currently unexploited, but implicit in the designation. © 2013 The Authors. Biological Reviews © 2013 Cambridge Philosophical Society.

Sm-p80-Based Schistosomiasis Vaccine: Preparation for Human Clinical Trials.

PubMed

Siddiqui, Afzal A; Siddiqui, Sabrina Z

2017-03-01

Mass antiparasitic drug administration programs and other control strategies have made important contributions in reducing the global prevalence of helminths. Schistosomiasis, however, continues to spread to new geographic areas. The advent of a viable vaccine and its deployment, coupled with existing control efforts, is expected to make significant headway towards sustained schistosomiasis control. In 2016, Science ranked the schistosomiasis vaccine as one of the top 10 vaccines that needs to be urgently developed. A vaccine that is effective against geographically distinct forms of intestinal/hepatic and urinary disease is essential to make a meaningful impact in global reduction of the disease burden. In this opinion article, we focus on salient features of schistosomiasis vaccines in different phases of the clinical development pipeline and highlight the Sm-p80-based vaccine which is now being prepared for human clinical trials. Copyright © 2016 Elsevier Ltd. All rights reserved.

Delay-induced rebounds in CO2 emissions and critical time-scales to meet global warming targets

NASA Astrophysics Data System (ADS)

Manoli, Gabriele; Katul, Gabriel G.; Marani, Marco

2016-12-01

While climate science debates are focused on the attainment of peak anthropogenic CO2 emissions and policy tools to reduce peak temperatures, the human-energy-climate system can hold "rebound" surprises beyond this peak. Following the second industrial revolution, global per capita CO2 emissions (cc) experienced a punctuated growth of about 100% every 60 years, mainly attributable to technological development and its global spread. A model of the human-energy-climate system capable of reproducing past punctuated dynamics shows that rebounds in global CO2 emissions emerge due to delays intrinsic to the diffusion of innovations. Such intrinsic delays in the adoption and spread of low-carbon emitting technologies, together with projected population growth, upset the warming target set by the Paris Agreement. To avoid rebounds and their negative climate effects, model calculations show that the diffusion of climate-friendly technologies must occur with lags one-order of magnitude shorter (i.e., ˜6 years) than the characteristic timescale of past punctuated growth in cc. Radically new strategies to globally implement the technological advances at unprecedented rates are needed if the current emission goals are to be achieved.

Human anthelminthic vaccines: Rationale and challenges.

PubMed

Hotez, Peter J; Strych, Ulrich; Lustigman, Sara; Bottazzi, Maria Elena

2016-06-24

Helminth infections are the most common afflictions of humankind, affecting almost every single person living in profound poverty. Through mass drug administration (MDA) we have seen sharp declines in the global prevalence of some helminth infections, including lymphatic filariasis, onchocerciasis, and ascariasis. However, since 1990, there has been no appreciable decrease in the global prevalence of hookworm infection, schistosomiasis, or food-borne trematodiases. Through the activities of a non-profit product development partnerships and two research institutes, a total of five human anthelmintic vaccines for hookworm infection (two) and schistosomiasis (three) have advanced from discovery through manufacture and are now in Phase 1 clinical testing. At least three additional antigens, including two for onchocerciasis and one for schistosomiasis, are also advancing through preclinical development with the intention of moving into the clinic soon. These preventive human anthelmintic vaccines could be used as stand-alone technologies administered to infants as part of the Expanded Program on Immunization (EPI), or together with anthelmintic drugs in programs linked to MDA. Significant hurdles though could hinder the advancement of these vaccines into later-stage clinical and product development and licensure. They include the absence of a major pharma partner (and the resultant access to adjuvants and industrial scale manufacturing expertise), an uncharted roadmap for how to introduce anthelmintic vaccines into appropriate health systems, uncertain global access and regulatory strategies that might need to rely on developing country vaccine manufacturers and national regulatory authorities, and the lack of innovative financing schemes. However, the public health and economic benefits of introducing these vaccines could be massive and therefore deserve international attention and support. Copyright © 2016 Elsevier Ltd. All rights reserved.

Assessment of Climatic and Anthropogenic Impacts on the Global Carbon Cycle Constrained by Atmospheric Measurements and Remote Sensing Data

NASA Technical Reports Server (NTRS)

Keeling, Charles D.; Piper, Stephen C.

2001-01-01

This grant aimed to establish how the global carbon cycle has responded and will respond to global change. We proposed to use models to predict measurements of atmospheric CO2 concentration and C-13/C-12 isotopic ratio, and thereby to establish how sources and sinks of atmospheric CO2 have been influenced by climatic change and human activities. As the work progressed we developed strategies involving finding regional sources and sinks of atmospheric CO2 by an inverse approach, and studying their seasonal and interannual variability.

Alternative polyadenylation: New insights from global analyses

PubMed Central

Shi, Yongsheng

2012-01-01

Recent studies have revealed widespread mRNA alternative polyadenylation (APA) in eukaryotes and its dynamic spatial and temporal regulation. APA not only generates proteomic and functional diversity, but also plays important roles in regulating gene expression. Global deregulation of APA has been demonstrated in a variety of human diseases. Recent exciting advances in the field have been made possible in a large part by high throughput analyses using newly developed experimental tools. Here I review the recent progress in global studies of APA and the insights that have emerged from these and other studies that use more conventional methods. PMID:23097429

A common agenda of global challenges. Japan and U.S. pool resources to tackle global issues including population and HIV / AIDS.

PubMed

1998-05-01

The Common Agenda for Cooperation in Global Perspective is a bilateral partnership established in 1993 between the US and Japan to address important global challenges of the 21st century such as global health and human development, including population and HIV/AIDS, global stability, protection of the global environment, and the advancement of science and technology. On the fifth anniversary of the agenda, representatives of the Japan and the US governments, international organizations, and private sectors discussed ways to further promote US-Japan cooperation under the agenda at a meeting held in Tokyo during March 12-13. Participants of the Common Agenda Open Forum also reviewed efforts made by Japan and the US under the agenda to address population and the environment. Forum participants focused upon developing new ideas for future cooperation between the governments, the private sector, and other nations, especially in the areas of health and the environment. The meeting was jointly organized by Japan's Ministry of Foreign Affairs and the US Department of State. Attention was also given during talks to diminishing international assistance budgets worldwide.

Enteric infections, diarrhea, and their impact on function and development

PubMed Central

Petri, William A.; Miller, Mark; Binder, Henry J.; Levine, Myron M.; Dillingham, Rebecca; Guerrant, Richard L.

2008-01-01

Enteric infections, with or without overt diarrhea, have profound effects on intestinal absorption, nutrition, and childhood development as well as on global mortality. Oral rehydration therapy has reduced the number of deaths from dehydration caused by infection with an enteric pathogen, but it has not changed the morbidity caused by such infections. This Review focuses on the interactions between enteric pathogens and human genetic determinants that alter intestinal function and inflammation and profoundly impair human health and development. We also discuss specific implications for novel approaches to interventions that are now opened by our rapidly growing molecular understanding. PMID:18382740

NASA Human Spaceflight Architecture Team: Lunar Surface Exploration Strategies

NASA Technical Reports Server (NTRS)

Mueller, Rob P.

2012-01-01

NASA s agency wide Human Spaceflight Architecture Team (HAT) has been developing Design Reference Missions (DRMs) to support the ongoing effort to characterize NASA s future human exploration strategy. The DRM design effort includes specific articulations of transportation and surface elements, technologies and operations required to enable future human exploration of various destinations including the moon, Near Earth Asteroids (NEAs) and Mars as well as interim cis-lunar targets. In prior architecture studies, transportation concerns have dominated the analysis. As a result, an effort was made to study the human utilization strategy at each specific destination and the resultant impacts on the overall architecture design. In particular, this paper considers various lunar surface strategies as representative scenarios that could occur in a human lunar return, and demonstrates their alignment with the internationally developed Global Exploration Roadmap (GER).

Education in the Muslim World: What's Next? AED Global Learning Group.

ERIC Educational Resources Information Center

Academy for Educational Development, Washington, DC.

This paper presents a discussion by a group of specialists on education in the Muslim world, looking at the United Nations Development Program's Arab Human Development Report of 2002, "Creating Opportunities for Future Generations," and noting three major deficits that need to be addressed: the freedom deficit (political freedom), the…

The Social Roots of a Global Community

ERIC Educational Resources Information Center

Soholt, Polli

2015-01-01

Polli Soholt points to normalization in the first plane as leading to the successful realization of the human personality, which is the basis of social development. Children who have cultivated concentration and purposeful work at an early age develop the virtues to become world citizens. Normalization can be assisted by certain practices: 1)…

The Development of a Socioscientific Issues-Based Curriculum Unit for Middle School Students: Global Warming Issue

ERIC Educational Resources Information Center

Atabey, Nejla; Topçu, Mustafa Sami

2017-01-01

In this study, we aimed at developing "Human and Environment" unit around SSI based instruction. We followed action research methodology in development and implementation of the unit. The participants of this study were 24 seventh graders students and the instruction was extended to eight and a half weeks, taking four hours in a week.…

Research and Activism about Girls' Education for Global Democracy: The Case of the Campaign "Etna, Volcano of Peace," Catania, Italy

ERIC Educational Resources Information Center

Cristaldi, Melita; Pampanini, Giovanni

2016-01-01

According to a progressive interpretation of human development, girls' education should form an integral part of a full democratic system. Nevertheless, girls' education is threatened and attacked in many ways in current societies, be they authoritarian or democratic societies, developing or developed ones. In this article the two authors, both…

The water footprint of human-made reservoirs for hydropower, irrigation, water supply, flood prevention, fishing and recreation on a global scale

NASA Astrophysics Data System (ADS)

Hogeboom, Rick; Knook, Luuk; Hoekstra, Arjen

2017-04-01

Increasing the availability of freshwater to meet growing and competing demands is on many policy agendas. The Sustainable Development Goals (SDGs) prescribe sustainable management of water for human consumption. For centuries humans have resorted to building dams to store water in periods of excess for use in times of shortage. Although dams and their reservoirs have made important contributions to human development, it is increasingly acknowledged that reservoirs can be substantial water consumers as well. We estimated the water footprint of human-made reservoirs on a global scale and attributed it to the various reservoir purposes (hydropower generation, residential and industrial water supply, irrigation water supply, flood protection, fishing and recreation) based on their economic value. We found that economic benefits from derived products and services from 2235 reservoirs globally, amount to 311 billion US dollar annually, with residential and industrial water supply and hydropower generation as major contributors. The water footprint associated with these benefits is the sum of the water footprint of dam construction (< 1 % contribution) and evaporation from the reservoir's surface area. The latter was calculated as an ensemble mean of four different methods for estimating open water evaporation. The total water footprint of reservoirs globally adds up to ˜104 km3yr-1. Attribution per purpose shows that, with a global average water footprint of 21,5 m3GJ,-1 hydropower on average is a water intensive form of energy. We contextualized the water footprint of reservoirs and their purposes with regard to the water scarcity level of the river basin in which they occur. We found the lion's share (55%) of the water footprint is located in non-water scarce basins and only 1% in year-round scarce basins. The purpose for which the reservoir is primarily used changes with increasing water scarcity, from mainly hydropower generation in non-scarce basins, to the (more essential) purposes residential and industrial water supply, irrigation and flood control in scarcer areas. The quantitative explication of how the burden of water consumption from reservoirs is shared between its beneficiaries as proposed in this study, can contribute to reaching the desired sustainable management of finite freshwater resources as proposed by SDG 6.

Interventions designed to prevent adverse programming outcomes resulting from exposure to maternal obesity during development

PubMed Central

Nathanielsz, PW; Ford, SP; Long, NM; Vega, CC; Reyes-Castro, LA; Zambrano, E

2013-01-01

Maternal obesity is a global epidemic affecting the developed and developing world. Human and animal studies indicate that maternal obesity programs development predisposing offspring to later-life chronic diseases. Several mechanisms act together to produce these adverse health problems. There is a need for effective interventions that prevent these outcomes and guide management in human pregnancy. We report here dietary and exercise intervention studies in both altricial and precocial species, rats and sheep, designed to prevent adverse offspring outcomes. Both interventions present exciting opportunities to at least in part prevent adverse metabolic and other outcomes in mother and offspring. PMID:24147928

Towards Increased Engagement of Geoscientists in Global Development Frameworks

NASA Astrophysics Data System (ADS)

Gill, Joel

2016-04-01

Geoscientists have the potential to make a significant contribution to tackling some of the major socio-environmental challenges of today, including extreme poverty, sustainable development, disaster risk reduction and climate change. This presentation explores the importance and social responsibility of geoscientists to engage in such work through understanding and supporting key global development frameworks. During 2015 the international community agreed three important agendas for change. Each framework relates to the intersection of environmental processes with human activities and behaviours, addressing significant challenges affecting society. The frameworks are (i) the UN Global Goals for Sustainable Development, (ii) the Sendai Framework for Disaster Risk Reduction 2015-2030, and (iii) subject to final confirmation at the time of writing, an agreement on climate change at the Paris Conference of the Parties - COP21. The UN Global Goals for Sustainable Development, for example, includes 17 goals aiming to end extreme poverty, fight inequality and ensure environmental sustainability. Specific goals relate to clean water and sanitation, clean and affordable energy, the development of resilient infrastructure, and the need for climate action. Given this context, here (i) a synthesis is presented of the role of geoscience in successfully achieving these major global development frameworks agreed in 2015, (ii) the ethical and social understanding that underpins effective engagement by geoscientists in the science-policy-practice interface is discussed, and (iii) this required ethical understanding is placed into the context of geoscience training and development needs. This approach demonstrates the importance of geoscientists from across all sectors and specialisms, engaging in the implementation, monitoring and evaluation of global development frameworks. It highlights the importance of a greater awareness and consideration of our ethical responsibilities in order to better support efforts to tackle major societal challenges.

Anthropology and Geosciences: Training and Collaboration Advancing Interdisciplinary Research of Human-environment Interaction

NASA Astrophysics Data System (ADS)

Brondizio, E.; Moran, E.

2005-05-01

Over the past thirteen years the Anthropological Center for Training and Research on Global Environmental Change (ACT) at Indiana University has pioneered the use of anthropological and environmental research approaches to address issues of land use change, and population-environment interaction, particularly in the Amazon. Our research and training objectives focus on how particular local populations manage resources and how those activities may be studied by integrating time-tested ethnographic methods, survey instruments, ecological field studies, and the spatial and temporal perspectives of remote sensing and Geographical Information Systems. The globalization of the environment crisis bears the risk of the research and training at universities being purely global or large scale in nature. This would fail to take into account the highly variable local causes of human activities or to discover sustainable solutions to the use, conservation, and restoration of human ecosystems. Our approach combines institutional and international collaboration, formal and hands-on laboratory and field activities developed within an interdisciplinary environment, but based on the strength of disciplinary programs. Over the past years, we have particularly emphasized collaboration between American and Brazilian scholars and students and intense work with local farmers and communities both during data collection and field research, as well as in returning data and results using different formats. In this paper, we address our experience, the challenges and advantages of theoretical and methodological development for students approaching interdisciplinary problems, innovations in linking levels of analysis, and new opportunities for international and collaborative training and research on human-environment interaction.

The biosphere: Problems and solutions; Proceedings of the Miami International Symposium on the Biosphere, Miami Beach, FL, April 23, 24, 1984

NASA Astrophysics Data System (ADS)

Veziroglu, T. N.

The objective of the Miami International Symposium on the Biosphere was to provide a forum for the presentation of the latest research findings on the environmental effects of human activities. The topics discussed are related to biosphere reserves, environmental aspects of hydrocarbon fuels, radioactivity and nuclear waste, land management, acid rains, water quality, water resources, coastal resources management, the pollution of rivers, industrial waste, economic development and the environment, health hazards and solutions, endangered species, environmentally compatible systems, space pollution, and global considerations. Attention is given to questions regarding global security and sustainable development, environethics as a global strategy for environmental quality, a gestalt approach to the environment, potential indicators for monitoring biosphere reserves, a review of regional impacts associated with the development of U.S. synthetic fuel resources, water resources in the Soviet Union, and pollution-free pesticides.

The globalization of education in medical ethics and humanities: evolving pedagogy at Weill Cornell Medical College in Qatar.

PubMed

del Pozo, Pablo Rodríguez; Fins, Joseph J

2005-02-01

The authors discuss their experience in implementing a Medical Ethics and Humanities course for premedical students at Weill Cornell Medical College in the Arabian Gulf emirate of Qatar. The course, first offered in 2003, is designed to prepare these students for the medical school curriculum to follow and to make global medical knowledge meaningful for their local context. Pedagogical challenges included the cross-cultural tensions that could emerge when introducing themes from Western medical ethics and humanities into this overwhelmingly Islamic context. The authors outline the response to this challenge and strategies to broaden student inquiry without engaging in indoctrination. This seminar-based course was designed around seven thematic areas of increasing biopsychosocial complexity, from nature and biology, to the patient, the physician, and the family, to broader questions of hospital care, the health care system, and the place of law in modern medicine. Readings from the literature of the Western and Arabic traditions were used, including selections by Hippocrates, Thomas, Kafka, Mahfouz, and Pellegrino. It is too early to know the ultimate impact of the course, but students demonstrated enthusiasm for ethics and the medical humanities and a willingness to consider new and novel ways of knowing. The authors anticipate that this grounding in the humanities will complement the students' work in the sciences and help further develop their nascent professional identities in an increasingly global medical community.

Changing global essential medicines norms to improve access to AIDS treatment: Lessons from Brazil

PubMed Central

Nunn, A.; Fonseca, E. Da; Gruskin, S.

2009-01-01

Brazil's large-scale, successful HIV/AIDS treatment programme is considered by many to be a model for other developing countries aiming to improve access to AIDS treatment. Far less is known about Brazil's important role in changing global norms related to international pharmaceutical policy, particularly international human rights, health and trade policies governing access to essential medicines. Prompted by Brazil's interest in preserving its national AIDS treatment policies during World Trade Organisation trade disputes with the USA, these efforts to change global essential medicines norms have had important implications for other countries, particularly those scaling up AIDS treatment. This paper analyses Brazil's contributions to global essential medicines policy and explains the relevance of Brazil's contributions to global health policy today. PMID:19333805

The Myers-Briggs Type Indicator as a Tool to Facilitate Learning Outcomes for Team Building in the Classroom

ERIC Educational Resources Information Center

Berry, Priscilla; Wood, Cindy; Thornton, Barry

2007-01-01

Globalization and domestic competition are forcing businesses to rethink the human resources utilization process, and one method for considering again this challenge is creating a team culture. One key to this process for human resources development is the understanding of how to create the most successful teams. The use of the Myers-Briggs Type…

Activation of mouse and human peroxisome proliferator-activated receptor-alpha (PPARα) by perfluoroalkyl acids (PFAAs) of 5, 7, 8, 11, and 12 carbon chain lengths in C05-1 cells.

EPA Science Inventory

PFAAs are surfactants that have been found globally in the environment and in tissues of humans and wildlife. They adversely affect perinatal survival and development in rodents and PPARα is involved in inducing these effects. Our previous study demonstrated that some PFAAs activ...

The scorecard on globalization 1980-2000: its consequences for economic and social well-being.

PubMed

Weisbrot, Mark; Baker, Dean; Kraev, Egor; Chen, Judy

2002-01-01

The era of globalization has brought substantially less progress than was achieved in the preceding 20 years. This study by the Center for Economic and Policy Research concludes that the data provide no evidence that the policies associated with globalization have improved outcomes for developing countries, and its findings challenge economists and policymakers who cite globalization as an engine of growth while pressing for policies that strengthen the trend. The study also served as a backdrop to the release of the United Nations Development Program's Human Development Report on July 11, 2001. Using standard measures of economic growth, health outcomes, education, and literacy, the CEPR study compares the progress achieved during the period preceding globalization, 1960-80, with the period from 1980 to 2000, which was characterized by the reduction of tariff and nontariff barriers to trade, the removal of restrictions on international investment flows, and increasing intervention by the International Monetary Fund and World Bank on a wide range of economic and policy issues. While the evidence presented here does not prove that the policies associated with globalization were responsible for the deterioration in economic performance, it does present a very strong prima facie case that some structural and policy changes implemented during the last two decades are at least partly responsible for these declines.

Progress integrating medical humanities into medical education: a global overview.

PubMed

Pfeiffer, Stefani; Chen, Yuchia; Tsai, Duujian

2016-09-01

The article reviews the most recent developments in integrating humanities into medical education. Global implications and future trends are illustrated. The main concern of medical humanities education is teaching professionalism; one important aspect that has emerged is the goal of nurturing emotion through reflexivity. Relating effectively to all stakeholders and being sensitive to inequitable power dynamics are essential for professional social accountability in modern medical contexts. Mediating doctors' understanding of the clinical encounter through creative arts and narrative is part of most recent pedagogic innovations aimed at motivating learners to become empowered, engaged and caring clinicians. Scenario-based and discursive-oriented evaluations of such activities should be aligned with the medical humanities' problem-based learning curriculum. Medical humanities education fosters professional reflexivity that is important for achieving patient-centered care. Countering insufficient empathy with reflective professionalism is an urgent challenge in medical education; to answer this need, creative arts and narrative understanding have emerged as crucial tools of medical humanities education. To ensure competent professional identity formation in the era of translational medicine, medical humanities programs have adopted scenario-based assessments through inclusion of different voices and emphasizing personal reflection and social critique.

Biology-inspired Microphysiological System Approaches to Solve the Prediction Dilemma of Substance Testing

PubMed Central

Marx, Uwe; Andersson, Tommy B.; Bahinski, Anthony; Beilmann, Mario; Beken, Sonja; Cassee, Flemming R.; Cirit, Murat; Daneshian, Mardas; Fitzpatrick, Susan; Frey, Olivier; Gaertner, Claudia; Giese, Christoph; Griffith, Linda; Hartung, Thomas; Heringa, Minne B.; Hoeng, Julia; de Jong, Wim H.; Kojima, Hajime; Kuehnl, Jochen; Luch, Andreas; Maschmeyer, Ilka; Sakharov, Dmitry; Sips, Adrienne J. A. M.; Steger-Hartmann, Thomas; Tagle, Danilo A.; Tonevitsky, Alexander; Tralau, Tewes; Tsyb, Sergej; van de Stolpe, Anja; Vandebriel, Rob; Vulto, Paul; Wang, Jufeng; Wiest, Joachim; Rodenburg, Marleen; Roth, Adrian

2017-01-01

Summary The recent advent of microphysiological systems – microfluidic biomimetic devices that aspire to emulate the biology of human tissues, organs and circulation in vitro – is envisaged to enable a global paradigm shift in drug development. An extraordinary US governmental initiative and various dedicated research programs in Europe and Asia have led recently to the first cutting-edge achievements of human single-organ and multi-organ engineering based on microphysiological systems. The expectation is that test systems established on this basis would model various disease stages, and predict toxicity, immunogenicity, ADME profiles and treatment efficacy prior to clinical testing. Consequently, this technology could significantly affect the way drug substances are developed in the future. Furthermore, microphysiological system-based assays may revolutionize our current global programs of prioritization of hazard characterization for any new substances to be used, for example, in agriculture, food, ecosystems or cosmetics, thus, replacing laboratory animal models used currently. Thirty-five experts from academia, industry and regulatory bodies present here the results of an intensive workshop (held in June 2015, Berlin, Germany). They review the status quo of microphysiological systems available today against industry needs, and assess the broad variety of approaches with fit-for-purpose potential in the drug development cycle. Feasible technical solutions to reach the next levels of human biology in vitro are proposed. Furthermore, key organ-on-a-chip case studies, as well as various national and international programs are highlighted. Finally, a roadmap into the future is outlined, to allow for more predictive and regulatory-accepted substance testing on a global scale. PMID:27180100

The role of vocational education in science and technology developement in the era of globalisation

NASA Astrophysics Data System (ADS)

Sudirman

2018-03-01

Globalization refers to a condition by which a world becomes competitive. In such a world, people are urged to do a job properly since they will be the asset to advance their nation further; this is also to strengthen the nation’s capital markets. Both the formal and informal vocational education is proposed to produce well-capable and highly-competitive graduates. This is considered important as one effort to deal with some challenges as well as a rapid advance in science and technology in the globalized world. This present study aims at exploring the contribution of vocational education in response to the development of science and technology in the globalized world. Furthermore, this study is a development of a notion that the vocational education system is proposed as a solution to the highly-competitive situation and challenges due to the globalization. To put it simply, vocational education significantly contributes towards the development of science and technology in a globalized world and how to deal with the situation. Such an education system equips the student with skills needed to become a productive and professional individual. This is also to produce better and competitive human resources that are able to compete with other nations.

The United Nations development programme initiative for sustainable energy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hurry, S.

1997-12-01

Energy is central to current concerns about sustainable human development, affecting economic and social development; economic growth, the local, national, regional, and global environment; the global climate; a host of social concerns, including poverty, population, and health, the balance of payments, and the prospects for peace. Energy is not an end in itself, but rather the means to achieve the goals of sustainable human development. The energy systems of most developing countries are in serious crisis involving insufficient levels of energy services, environmental degradation, inequity, poor technical and financial performance, and capital scarcity. Approximately 2.5 billion people in the developingmore » countries have little access to commercial energy supplies. Yet the global demand for energy continues to grow: total primary energy is projected to grow from 378 exajoules (EJ) per year in 1990 to 571 EJ in 2020, and 832 EJ in 2050. If this increase occurs using conventional approaches and energy sources, already serious local (e.g., indoor and urban air pollution), regional (eg., acidification and land degradation), and global (e.g., climate change) environmental problems will be critically aggravated. There is likely to be inadequate capital available for the needed investments in conventional energy sources. Current approaches to energy are thus not sustainable and will, in fact, make energy a barrier to socio-economic development. What is needed now is a new approach in which energy becomes an instrument for sustainable development. The two major components of a sustainable energy strategy are (1) more efficient energy use, especially at the point of end-use, and (2) increased use of renewable sources of energy. The UNDP Initiative for Sustainable Energy (UNISE) is designed to harness opportunities in these areas to build upon UNDP`s existing energy activities to help move the world toward a more sustainable energy strategy by helping program countries.« less

A bioinformatics roadmap for the human vaccines project.

PubMed

Scheuermann, Richard H; Sinkovits, Robert S; Schenkelberg, Theodore; Koff, Wayne C

2017-06-01

Biomedical research has become a data intensive science in which high throughput experimentation is producing comprehensive data about biological systems at an ever-increasing pace. The Human Vaccines Project is a new public-private partnership, with the goal of accelerating development of improved vaccines and immunotherapies for global infectious diseases and cancers by decoding the human immune system. To achieve its mission, the Project is developing a Bioinformatics Hub as an open-source, multidisciplinary effort with the overarching goal of providing an enabling infrastructure to support the data processing, analysis and knowledge extraction procedures required to translate high throughput, high complexity human immunology research data into biomedical knowledge, to determine the core principles driving specific and durable protective immune responses.

Human trafficking law and social structures.

PubMed

Wooditch, Alese

2012-08-01

Human trafficking has only recently emerged at the forefront of policy reform, even in developed nations. Yet, heightened awareness of the issue has not translated into effective policy as the majority of nations have ineffective antitrafficking practices; many countries have failed to criminalize human trafficking, whereas others do not actively enforce statutes in place. By applying Black's theory of law, this study offers a preliminary understanding into the variation of global prosecutorial efforts in human trafficking and adequacy of antitrafficking law. To isolate this relationship, the effects of trafficking markets are controlled. As with prior research, the study finds limited support for the theory. The article concludes with a discussion on the implications of the quantity of antitrafficking law and morphology association for policy development.

Global Urban Mapping and Modeling for Sustainable Urban Development

NASA Astrophysics Data System (ADS)

Zhou, Y.; Li, X.; Asrar, G.; Yu, S.; Smith, S.; Eom, J.; Imhoff, M. L.

2016-12-01

In the past several decades, the world has experienced fast urbanization, and this trend is expected to continue for decades to come. Urbanization, one of the major land cover and land use changes (LCLUC), is becoming increasingly important in global environmental changes, such as urban heat island (UHI) growth and vegetation phenology change. Better scientific insights and effective decision-making unarguably require reliable science-based information on spatiotemporal changes in urban extent and their environmental impacts. In this study, we developed a globally consistent 20-year urban map series to evaluate the time-reactive nature of global urbanization from the nighttime lights remote sensing data, and projected future urban expansion in the 21st century by employing an integrated modeling framework (Zhou et al. 2014, Zhou et al. 2015). We then evaluated the impacts of urbanization on building energy use and vegetation phenology that affect both ecosystem services and human health. We extended the modeling capability of building energy use in the Global Change Assessment Model (GCAM) with consideration of UHI effects by coupling the remote sensing based urbanization modeling and explored the impact of UHI on building energy use. We also investigated the impact of urbanization on vegetation phenology by using an improved phenology detection algorithm. The derived spatiotemporal information on historical and potential future urbanization and its implications in building energy use and vegetation phenology will be of great value in sustainable urban design and development for building energy use and human health (e.g., pollen allergy), especially when considered together with other factors such as climate variability and change. Zhou, Y., S. J. Smith, C. D. Elvidge, K. Zhao, A. Thomson & M. Imhoff (2014) A cluster-based method to map urban area from DMSP/OLS nightlights. Remote Sensing of Environment, 147, 173-185. Zhou, Y., S. J. Smith, K. Zhao, M. Imhoff, A. Thomson, B. Bond-Lamberty, G. R. Asrar, X. Zhang, C. He & C. D. Elvidge (2015) A global map of urban extent from nightlights. Environmental Research Letters, 10, 054011.

The WHO's new End TB Strategy in the post-2015 era of the Sustainable Development Goals.

PubMed

Lönnroth, Knut; Raviglione, Mario

2016-03-01

The WHO's new End TB Strategy 2016-2035 has evolved from previous global strategies to respond to old and new challenges and take advantage of new opportunities. It frames the global fight against TB as a development, social justice and human rights issue, while re-emphasizing the public health and clinical fundaments of TB care and prevention. In this commentary, we outline how TB prevention, care and control will both benefit from and contribute to the achievement of the new Sustainable Development Goals that were recently adopted at the United Nations. © The author 2016. The World Health Organization has granted Oxford University Press permission for the reproduction of this article.

Future directions of ecosystem science

USGS Publications Warehouse

Baron, Jill S.; Galvin, Kathleen A.

1990-01-01

Scientific knowledge about ecosystem structure and function has expanded greatly during the past few decades. Terrestrial and aquatic nutrient cycling, ecosystem energetics, population dynamics, belowground processes, and food webs have been studied at the plot, stand, watershed, and landscape levels at many locations around the globe. Ideas about terrestrial-atmospheric interactions and human interference in these processes have changed dramatically. There is new appreciation of the need to incorporate into ecosystem studies the interactions between human populations and the ecosystem, not only because humans affect ecosystem processes, but because these systems support human populations (Glantz 1988, Holden 1988, Parry et al. 1988, WCED 1987). Recent advances in ecosystem science are due, in part, to technological improvements in computing power, new laboratory and field physical and chemical analytical techniques, and satellite imagery for remote sensing of Earth's structure and dynamics. Modeling and geographic information systems have provided the capability for integrating multiple data sets with process simulations to generate hypotheses about regional ecosystem function. Concurrent with these scientific developments has been a growing concern about the links between the health of the environment and world-wide industrial, land, and resource-management practices. Environmental damage at the local level was widely recognized in the 1960s, prompting the environmental movement of that decade. Regional environmental problems with multiple effects and politically difficult solutions have been perceived more recently; the issue of acidic deposition provides an example of such a second-generation concern (Clark and Holling 1985). Today there is a growing awareness of global-scale environmental degradation brought about by the combined actions of all peoples on Earth (Clark 1989, Woodmansee et al. 1988). The three levels of environmental concern--local, regional, and global--have not replaced one another (Clark and Holling 1985). Instead, the effects are superimposed, creating what some perceive as impending global environmental crisis (Clark 1989, MacNeill 1989, WCED 1987). Public demands are developing for economic, political, social, and environmental efforts directed toward creating a state of global sustainability.

The Role of Cis-Lunar Space in Future Global Space Exploration

NASA Technical Reports Server (NTRS)

Bobskill, Marianne R.; Lupisella, Mark L.

2012-01-01

Cis-lunar space offers affordable near-term opportunities to help pave the way for future global human exploration of deep space, acting as a bridge between present missions and future deep space missions. While missions in cis-lunar space have value unto themselves, they can also play an important role in enabling and reducing risk for future human missions to the Moon, Near-Earth Asteroids (NEAs), Mars, and other deep space destinations. The Cis-Lunar Destination Team of NASA's Human Spaceflight Architecture Team (HAT) has been analyzing cis-lunar destination activities and developing notional missions (or "destination Design Reference Missions" [DRMs]) for cis-lunar locations to inform roadmap and architecture development, transportation and destination elements definition, operations, and strategic knowledge gaps. The cis-lunar domain is defined as that area of deep space under the gravitational influence of the earth-moon system. This includes a set of earth-centered orbital locations in low earth orbit (LEO), geosynchronous earth orbit (GEO), highly elliptical and high earth orbits (HEO), earth-moon libration or "Lagrange" points (E-ML1 through E-ML5, and in particular, E-ML1 and E-ML2), and low lunar orbit (LLO). To help explore this large possibility space, we developed a set of high level cis-lunar mission concepts in the form of a large mission tree, defined primarily by mission duration, pre-deployment, type of mission, and location. The mission tree has provided an overall analytical context and has helped in developing more detailed design reference missions that are then intended to inform capabilities, operations, and architectures. With the mission tree as context, we will describe two destination DRMs to LEO and GEO, based on present human space exploration architectural considerations, as well as our recent work on defining mission activities that could be conducted with an EML1 or EML2 facility, the latter of which will be an emphasis of this paper, motivated in part by recent interest expressed at the Global Exploration Roadmap Stakeholder meeting. This paper will also explore the links between this HAT Cis-Lunar Destination Team analysis and the recently released ISECG Global Exploration Roadmap and other potential international considerations, such as preventing harmful interference to radio astronomy observations in the shielded zone of the moon.

The spatial structure of transnational human activity.

PubMed

Deutschmann, Emanuel

2016-09-01

Starting from conflictive predictions of hitherto disconnected debates in the natural and social sciences, this article examines the spatial structure of transnational human activity (THA) worldwide (a) across eight types of mobility and communication and (b) in its development over time. It is shown that the spatial structure of THA is similar to that of animal displacements and local-scale human motion in that it can be approximated by Lévy flights with heavy tails that obey power laws. Scaling exponent and power-law fit differ by type of THA, being highest in refuge-seeking and tourism and lowest in student exchange. Variance in the availability of resources and opportunities for satisfying associated needs appears to explain these differences. Over time (1960-2010), the Lévy-flight pattern remains intact and remarkably stable, contradicting the popular notion that socio-technological trends lead to a "death of distance." Humans have not become more "global" over time, they rather became more mobile in general, i.e. they move and communicate more at all distances. Hence, it would be more adequate to speak of "mobilization" than of "globalization." Longitudinal change occurs only in some types of THA and predominantly at short distances, indicating regional rather than global shifts. Copyright © 2016 Elsevier Inc. All rights reserved.

How accessible are coral reefs to people? A global assessment based on travel time.

PubMed

Maire, Eva; Cinner, Joshua; Velez, Laure; Huchery, Cindy; Mora, Camilo; Dagata, Stephanie; Vigliola, Laurent; Wantiez, Laurent; Kulbicki, Michel; Mouillot, David

2016-04-01

The depletion of natural resources has become a major issue in many parts of the world, with the most accessible resources being most at risk. In the terrestrial realm, resource depletion has classically been related to accessibility through road networks. In contrast, in the marine realm, the impact on living resources is often framed into the Malthusian theory of human density around ecosystems. Here, we develop a new framework to estimate the accessibility of global coral reefs using potential travel time from the nearest human settlement or market. We show that 58% of coral reefs are located < 30 min from the nearest human settlement. We use a case study from New Caledonia to demonstrate that travel time from the market is a strong predictor of fish biomass on coral reefs. We also highlight a relative deficit of protection on coral reef areas near people, with disproportional protection on reefs far from people. This suggests that conservation efforts are targeting low-conflict reefs or places that may already be receiving de facto protection due to their isolation. Our global assessment of accessibility in the marine realm is a critical step to better understand the interplay between humans and resources. © 2016 John Wiley & Sons Ltd/CNRS.

Working Group Reports and Presentations: Mars Science and Exploration

NASA Technical Reports Server (NTRS)

Beaty, David

2006-01-01

In Mars, the spirit of exploring an exciting and rewarding new frontier is alive. Mars not only offers a unique destination for exploration, but it is also a critical destination for the advancement of human society and preservation of humanity. The exploration of Mars will provide significant social and technological benefits to enhance life on Earth as well. International cooperation will not only be essential to the success of a human presence on Mars, but development of such interactions will jumpstart collaboration on global issues. The eventual commercialization of space holds tremendous opportunities for economic growth. Finally, there is an undeniable basic human need to explore and define our place in the universe. The overarching theme that ties together all of these reasons for exploration is to inspire and unite the global community to pursue a common cause that is much larger than disagreements over ethnic differences or national borders. Continuous inspiration of the public, the scientific community, and the community of Earth are required in order to explore Mars.

The ethics of developed nations recruiting nurses from developing countries: the case of Malawi.

PubMed

Muula, Adamson S; Mfutso-Bengo, Joseph M; Makoza, Joan; Chatipwa, Elita

2003-07-01

There is currently a global shortage of nurses. Developing countries such as Malawiare among those hardest hit by this shortage. The demands on available nurses have increased and at the same time there is a lack of interest in becoming a nurse owing to the poor working conditions among those still employed in the service. It is questionable if developed nations should recruit nurses from countries such as Malawi, where severe human resource constraints are being experienced. We argue in this article that the current phenomenon of nurses leaving developing nations for western countries is complex. Human rights issues of individual autonomy and public interest are at stake.

Mitigation/adaptation and health: health policymaking in the global response to climate change and implications for other upstream determinants.

PubMed

Wiley, Lindsay F

2010-01-01

The time is ripe for innovation in global health governance if we are to achieve global health and development objectives in the face of formidable challenges. Integration of global health concerns into the law and governance of other, related disciplines should be given high priority. This article explores opportunities for health policymaking in the global response to climate change. Climate change and environmental degradation will affect weather disasters, food and water security, infectious disease patterns, and air pollution. Although scientific research has pointed to the interdependence of the global environment and human health, policymakers have been slow to integrate their approaches to environmental and health concerns. A robust response to climate change will require improved integration on two fronts: health concerns must be given higher priority in the response to climate change and threats associated with climate change and environmental degradation must be more adequately addressed by global health law and governance. The mitigation/adaptation response paradigm developing within and beyond the United Nations Framework Convention on Climate Change provides a useful framework for thinking about global health law and governance with respect to climate change, environmental degradation, and possibly other upstream determinants of health as well. © 2010 American Society of Law, Medicine & Ethics, Inc.

Does Globalization Affect Human Well-Being?

ERIC Educational Resources Information Center

Tsai, Ming-Chang

2007-01-01

The prevailing theorizing of globalization's influence of human well-being suggests to assess both the favorable and unfavorable outcomes. This study formulates a dialectical model, adopts a comprehensive globalization measure and uses a three-wave panel data during 1980-2000 to empirically test direct and indirect effects of global flows' human…

What could a strengthened right to health bring to the post-2015 health development agenda?: interrogating the role of the minimum core concept in advancing essential global health needs.

PubMed

Forman, Lisa; Ooms, Gorik; Chapman, Audrey; Friedman, Eric; Waris, Attiya; Lamprea, Everaldo; Mulumba, Moses

2013-12-01

Global health institutions increasingly recognize that the right to health should guide the formulation of replacement goals for the Millennium Development Goals, which expire in 2015. However, the right to health's contribution is undercut by the principle of progressive realization, which links provision of health services to available resources, permitting states to deny even basic levels of health coverage domestically and allowing international assistance for health to remain entirely discretionary. To prevent progressive realization from undermining both domestic and international responsibilities towards health, international human rights law institutions developed the idea of non-derogable "minimum core" obligations to provide essential health services. While minimum core obligations have enjoyed some uptake in human rights practice and scholarship, their definition in international law fails to specify which health services should fall within their scope, or to specify wealthy country obligations to assist poorer countries. These definitional gaps undercut the capacity of minimum core obligations to protect essential health needs against inaction, austerity and illegitimate trade-offs in both domestic and global action. If the right to health is to effectively advance essential global health needs in these contexts, weaknesses within the minimum core concept must be resolved through innovative research on social, political and legal conceptualizations of essential health needs. We believe that if the minimum core concept is strengthened in these ways, it will produce a more feasible and grounded conception of legally prioritized health needs that could assist in advancing health equity, including by providing a framework rooted in legal obligations to guide the formulation of new health development goals, providing a baseline of essential health services to be protected as a matter of right against governmental claims of scarcity and inadequate international assistance, and empowering civil society to claim fulfillment of their essential health needs from domestic and global decision-makers.

What could a strengthened right to health bring to the post-2015 health development agenda?: interrogating the role of the minimum core concept in advancing essential global health needs

PubMed Central

2013-01-01

Background Global health institutions increasingly recognize that the right to health should guide the formulation of replacement goals for the Millennium Development Goals, which expire in 2015. However, the right to health’s contribution is undercut by the principle of progressive realization, which links provision of health services to available resources, permitting states to deny even basic levels of health coverage domestically and allowing international assistance for health to remain entirely discretionary. Discussion To prevent progressive realization from undermining both domestic and international responsibilities towards health, international human rights law institutions developed the idea of non-derogable “minimum core” obligations to provide essential health services. While minimum core obligations have enjoyed some uptake in human rights practice and scholarship, their definition in international law fails to specify which health services should fall within their scope, or to specify wealthy country obligations to assist poorer countries. These definitional gaps undercut the capacity of minimum core obligations to protect essential health needs against inaction, austerity and illegitimate trade-offs in both domestic and global action. If the right to health is to effectively advance essential global health needs in these contexts, weaknesses within the minimum core concept must be resolved through innovative research on social, political and legal conceptualizations of essential health needs. Summary We believe that if the minimum core concept is strengthened in these ways, it will produce a more feasible and grounded conception of legally prioritized health needs that could assist in advancing health equity, including by providing a framework rooted in legal obligations to guide the formulation of new health development goals, providing a baseline of essential health services to be protected as a matter of right against governmental claims of scarcity and inadequate international assistance, and empowering civil society to claim fulfillment of their essential health needs from domestic and global decision-makers. PMID:24289096

Global Assessment of Exploitable Surface Reservoir Storage under Climate Change

NASA Astrophysics Data System (ADS)

Liu, L.; Parkinson, S.; Gidden, M.; Byers, E.; Satoh, Y.; Riahi, K.

2016-12-01

Surface water reservoirs provide us with reliable water supply systems, hydropower generation, flood control, and recreation services. Reliable reservoirs can be robust measures for water security and can help smooth out challenging seasonal variability of river flows. Yet, reservoirs also cause flow fragmentation in rivers and can lead to flooding of upstream areas, thereby displacing existing land-uses and ecosystems. The anticipated population growth, land use and climate change in many regions globally suggest a critical need to assess the potential for appropriate reservoir capacity that can balance rising demands with long-term water security. In this research, we assessed exploitable reservoir potential under climate change and human development constraints by deriving storage-yield relationships for 235 river basins globally. The storage-yield relationships map the amount of storage capacity required to meet a given water demand based on a 30-year inflow sequence. Runoff data is simulated with an ensemble of Global Hydrological Models (GHMs) for each of five bias-corrected general circulation models (GCMs) under four climate change pathways. These data are used to define future 30-year inflows in each river basin for time period between 2010 and 2080. The calculated capacity is then combined with geographical information of environmental and human development exclusion zones to further limit the storage capacity expansion potential in each basin. We investigated the reliability of reservoir potentials across different climate change scenarios and Shared Socioeconomic Pathways (SSPs) to identify river basins where reservoir expansion will be particularly challenging. Preliminary results suggest large disparities in reservoir potential across basins: some basins have already approached exploitable reserves, while some others display abundant potential. Exclusions zones pose significant impact on the amount of actual exploitable storage and firm yields worldwide: 30% of reservoir potential would be unavailable because of land occupation by environmental and human development. Results from this study will help decision makers to understand the reliability of infrastructure systems particularly sensitive to future water availability.

New antituberculous drugs derived from natural products: current perspectives and issues in antituberculous drug development.

PubMed

Igarashi, Masayuki; Ishizaki, Yoshimasa; Takahashi, Yoshiaki

2017-11-01

Tuberculosis is one of the most common and challenging infectious diseases worldwide. Especially, the lack of effective chemotherapeutic drugs for tuberculosis/human immunodeficiency virus co-infection and prevalence of multidrug-resistant and extensively drug-resistant tuberculosis remain to be serious clinical problems. Development of new drugs is a potential solution to fight tuberculosis. In this decade, the development status of new antituberculous drugs has been greatly advanced by the leading role of international organizations such as the Global Alliance for Tuberculosis Drug Development, Stop Tuberculosis Partnership and Global Health Innovative Technology Fund. In this review, we introduce the development status of new drugs for tuberculosis, focusing on those derived from natural products.The Journal of Antibiotics advance online publication, 1 November 2017; doi:10.1038/ja.2017.126.

The Human Microbiota, Infectious Disease, and Global Health: Challenges and Opportunities.

PubMed

Waldman, Abraham J; Balskus, Emily P

2018-01-12

Despite significant advances in treating infectious diseases worldwide, morbidity and mortality associated with pathogen infection remains extraordinarily high and represents a critical scientific and global health challenge. Current strategies to combat these infectious agents include a combination of vaccines, small molecule drugs, increased hygiene standards, and disease-specific interventions. While these approaches have helped to drastically reduce the incidence and number of deaths associated with infection, continued investment in current strategies and the development of novel therapeutic approaches will be required to address these global health threats. Recently, human- and vector-associated microbiotas, the assemblages of microorganisms living on and within their hosts, have emerged as a potentially important factor mediating both infection risk and disease progression. These complex microbial communities are involved in intricate and dynamic interactions with both pathogens as well as the innate and adaptive immune systems of their hosts. Here, we discuss recent findings that have illuminated the importance of resident microbiotas in infectious disease, emphasizing opportunities for novel therapeutic intervention and future challenges for the field. Our discussion will focus on four major global health threats: tuberculosis, malaria, HIV, and enteric/diarrheal diseases. We hope this Perspective will highlight the many opportunities for chemists and chemical biologists in this field as well as inspire efforts to elucidate the mechanisms underlying established disease correlations, identify novel microbiota-based risk factors, and develop new therapeutic interventions.

The Global Flows of Metals and Minerals

USGS Publications Warehouse

Rogich, Donald G.; Matos, Grecia R.

2008-01-01

This paper provides a preliminary review of the trends in worldwide metals and industrial minerals production and consumption based on newly developed global metals and minerals Material Flow Accounts (MFA). The MFA developed encompass data on extraction and consumption for 25 metal and mineral commodities, on a country-by-country and year-by-year basis, for the period 1970 to 2004. The data-base, jointly developed by the authors, resides with the U.S. Geological Survey (USGS) as individual commodity Excel workbooks and within a Filemaker data management system for use in analysis. Numerous national MFA have been developed to provide information on the industrial metabolism of individual countries. These MFA include material flows associated with the four commodity categories of goods that are inputs to a country's economy, agriculture, forestry, metals and minerals, and nonrenewable organic material. In some cases, the material flows associated with the creation and maintenance of the built infrastructure (such as houses, buildings, roads, airports, dams, and so forth) were also examined. The creation of global metals and industrial minerals flows is viewed as a first step in the creation of comprehensive global MFA documenting the historical and current flows of all of the four categories of physical goods that support world economies. Metals and minerals represent a major category of nonrenewable resources that humans extract from and return to the natural ecosystem. As human populations and economies have increased, metals and industrial minerals use has increased concomitantly. This dramatic growth in metals and minerals use has serious implications for both the availability of future resources and the health of the environment, which is affected by the outputs associated with their use. This paper provides an overview of a number of the trends observed by examining the database and suggests areas for future study.

Global opportunities for mariculture development to promote human nutrition

PubMed Central

Molina, Renato; Wilson, Margaret; Halpern, Benjamin S.

2018-01-01

An estimated two billion people worldwide currently suffer from micronutrient malnutrition, and almost one billion are calorie deficient. Providing adequate nutrition is a growing global challenge. Seafood is one of the most important sources of both protein and micronutrients for many, yet production from wild capture fisheries has stagnated. In contrast, aquaculture is the world’s fastest-growing food production sector and now supplies over half of all seafood consumed globally. Mariculture, or the farming of brackish and marine species, accounts for roughly one-third of all aquaculture production and has received increasing attention as a potential supplement for wild-caught marine fisheries. By analyzing global patterns in seafood reliance, malnutrition levels, and economic opportunity, this study identifies where mariculture has the greatest potential to improve human nutrition. We calculate a mariculture opportunity index for 117 coastal nations by drawing on a diverse set of seafood production, trade, consumption, and nutrition data. Seventeen primary variables are combined into country-level scores for reliance on seafood, opportunity for nutritional improvement, and opportunity for economic development of mariculture. The final mariculture opportunity score identifies countries with high seafood reliance combined with high nutritional and economic opportunity scores. We find that island nations in Southeast Asia and the Caribbean are consistently identified as countries with high mariculture opportunity. In other regions, nutritional and economic opportunity scores are not significantly correlated, and we discuss the implications of this finding for crafting appropriate development policy. Finally, we identify key challenges to ameliorating malnutrition through mariculture development, including insufficient policy infrastructure, government instability, and ensuring local consumption of farmed fish. Our analysis is an important step towards prioritizing nations where the economic and nutritional benefits of expanding mariculture may be jointly captured. PMID:29761051

Our Changing Planet: The FY 1993 US Global Change Research Program. A report by the Committee on Earth and Environmental Sciences, a supplement to the US President's fiscal year 1993 budget

NASA Technical Reports Server (NTRS)

1992-01-01

The U.S. Global Change Reasearch Program (USGCRP) was established as a Presidential initiative in the FY-1990 Budget to help develop sound national and international policies related to global environmental issues, particularly global climate change. The USGCRP is implemented through a priority-driven scientific research agenda that is designed to be integrated, comprehensive, and multidisciplinary. It is designed explicitly to address scientific uncertainties in such areas as climate change, ozone depletion, changes in terrestrial and marine productivity, global water and energy cycles, sea level changes, the impact of global changes on human health and activities, and the impact of anthropogenic activities on the Earth system. The USGCRP addresses three parallel but interconnected streams of activity: documenting global change (observations); enhancing understanding of key processes (process research); and predicting global and regional environmental change (integrated modeling and prediction).

[Mycology in the 21st century: crisis and revitalization].

PubMed

Silar, Philippe

2013-01-01

Although they are key players in the biosphere and have important roles in human industry, agriculture and health, fungi are largely understudied and, more disturbingly, often underrepresented in biology classes at all levels. Nevertheless, it is most likely that mycology will soon undergo a renewal of interest. Firstly, because fungi are becoming more prominent in human concerns, as their impact on human, animal and ecosystem health are increasing, animal and plant biologists become more aware of their importance. Moreover, mycologists have organized to make their discipline more visible and to enable large scale scientific projects, such as the global analyses of fungal phylogeny and of their genome structure, function and evolution. This, combined with the next generation of sequencing technologies, now permits an in depth and global understanding on how fungi are organized and how they function. It also enables the development of strategies that will help to fight fungi when they negatively interfere with human concerns, as in human mycosis, or to use them in industries such as in renewable energy usage. © Société de Biologie, 2014.

Night-time lights as a proxy of human pressure on freshwater resources

NASA Astrophysics Data System (ADS)

Ceola, Serena; Montanari, Alberto; Laio, Francesco

2017-04-01

The presence and availability of freshwater resources at the global scale control the dynamics and the biodiversity of river ecosystems, as well as the human development and the security of people and economies. The increasing human pressure on freshwater is known to potentially drive significant alterations on both ecohydrological and social dynamics. To date, a spatially-detailed snapshot (i.e. single in time) analysis of human water security and river biodiversity threats revealed that the majority of the world's population and river ecosystems are exposed to high levels of endangerment. However, the temporal evolution of these effects at the global scale is still unexplored. To this aim, moving from the recent progress on remote sensing techniques, we employed yearly averaged night-time light images available from 1992 to 2013 as a proxy of anthropogenic presence and activity and we investigated how threats to human water security and river biodiversity evolved in time in 405 major river basins. Our results show a consistent correlation between nightlights and ecohydrological and threats, providing innovative support for freshwater resources management.

Power-law Growth and Punctuated Equilibrium Dynamics in Water Resources Systems

NASA Astrophysics Data System (ADS)

Parolari, A.; Katul, G. G.; Porporato, A. M.

2015-12-01

The global rise in population-driven water scarcity and recent appreciation of strong dynamic coupling between human and natural systems has called for new approaches to predict the future sustainability of regional and global water resources systems. The dynamics of coupled human-water systems are driven by a complex set of social, environmental, and technological factors. Present projections of water resources systems range from a finite carrying capacity regulated by accessible freshwater, or `peak renewable water,' to punctuated evolution with new supplied and improved efficiency gained from technological and social innovation. However, these projections have yet to be quantified from observations or in a comprehensive theoretical framework. Using data on global water withdrawals and storage capacity of regional water supply systems, non-trivial dynamics are identified in water resources systems development over time, including power-law growth and punctuated equilibria. Two models are introduced to explain this behavior: (1) a delay differential equation and (2) a power-law with log-periodic oscillations, both of which rely on past conditions (or system memory) to describe the present rate of growth in the system. In addition, extension of the first model demonstrates how system delays and punctuated equilibria can emerge from coupling between human population growth and associated resource demands. Lastly, anecdotal evidence is used to demonstrate the likelihood of power-law growth in global water use from the agricultural revolution 3000 BC to the present. In a practical sense, the presence of these patterns in models with delayed oscillations suggests that current decision-making related to water resources development results from the historical accumulation of resource use decisions, technological and social changes, and their consequences.

The contributions of human factors and ergonomics to a sustainable minerals industry.

PubMed

Horberry, Tim; Burgess-Limerick, Robin; Fuller, Ruth

2013-01-01

This article describes examples of the application of human factors research and development work to a sustainable minerals industry. It begins by outlining human-related aspects of the minerals industry and the key human factors work previously undertaken in this domain. The focus then switches to sustainability in the minerals industry. Sustainability principles are introduced and illustrations provided of how human factors research and development work fits within such a framework. Three case studies of human factors in the minerals industry research are presented and the sustainability implications in each case study are highlighted. Finally, future trends related to human factors work in a sustainable minerals industry are addressed, in particular the opportunities and possible adverse consequences that increasing deployment of mining automation might bring. Minerals industries are a major global activity with significant sustainability implications. Aspects of sustainability in mining are examined using three case studies. These illustrate the contribution of human factors/ergonomics in reducing risks; developing emergency response management systems; and the value of participatory ergonomics in improving the design of mining equipment.

Increasing population and declining biological resources in the context of global change and globalization.

PubMed

Ramakrishnan, P S

2001-11-01

In the context of over-consumption of natural resources in the name of development and rapid industrialization by a small section of the human population that is rapidly growing, the world is currently faced with a variety of environmental uncertainties. 'Global change' covering a whole variety of ecological issues, and 'globalization' in an economic sense, are two major phenomena that are responsible for these uncertainties. There is increasing evidence to suggest that the developing countries more than the developed, particularly the marginalized traditional (those living close to nature and natural resources) societies would be the worst sufferers. In order to cope with this problem in a situation where the traditional societies have to cope with rapidly depleting biodiversity on which they are dependant for their livelihood, there is an urgent need to explore additional pathways for sustainable management of natural resources and societal development. Such pathways should be based on a landscape management strategy, that takes into consideration the rich traditional ecological knowledge (TEK) that these societies have. This is critical because TEK is the connecting link between conservation and sustainable development. This paper explores the possibilities in this direction through a balanced approach to development, that links the 'traditional' with the 'modern', in a location-specific way.

Linking Regional Satellite Observations with Coupled Human-Ecological Systems in Global Drylands

NASA Astrophysics Data System (ADS)

Hutchinson, C.; Reynolds, J. F.

2009-12-01

The African Sahel has attracted consistent attention since a series of droughts in the 1970s and 1980s caused widespread famine and land degradation (desertification). These events spawned international conventions and sustained development efforts to increase food security and reverse poverty for the local populations, and to arrest environmental degradation. Since 1985, several studies using satellite data have described a general “greening” in response to increased rainfall trends. However, some areas show more greening while others less greening than can be explained by precipitation alone (Glob. Env. Change 15- 2005). The debated question is how to explain the residual changes: management, policy, human adaptation, or something else? Placing results in an human-ecological framework could help answer this question. Providing a meaningful assessment will allow national and international agencies to evaluate the effectiveness of alternative approaches to poverty alleviation and environmental restoration in drylands at regional and global scales.

Modeling infectious disease dynamics in the complex landscape of global health

PubMed Central

Heesterbeek, Hans; Anderson, Roy; Andreasen, Viggo; Bansal, Shweta; De Angelis, Daniela; Dye, Chris; Eames, Ken; Edmunds, John; Frost, Simon; Funk, Sebastian; Hollingsworth, Deirdre; House, Thomas; Isham, Valerie; Klepac, Petra; Lessler, Justin; Lloyd-Smith, James; Metcalf, Jessica; Mollison, Denis; Pellis, Lorenzo; Pulliam, Juliet; Roberts, Mick; Viboud, Cecile

2015-01-01

Despite some notable successes in the control of infectious diseases, transmissible pathogens still pose an enormous threat to human and animal health. The ecological and evolutionary dynamics of infections play out on a wide range of interconnected temporal, organizational and spatial scales, which even within a single pathogen often span hours to months, cellular to ecosystem levels, and local to pandemic spread. Some pathogens are directly transmitted between individuals of a single species, while others circulate among multiple hosts, need arthropod vectors, or can survive in environmental reservoirs. Many factors, including increasing antimicrobial resistance, increased human connectivity, and dynamic human behavior, raise prevention and control from formerly national to international issues. In the face of this complexity, mathematical models offer essential tools for synthesizing information to understand epidemiological patterns, and for developing the quantitative evidence base for decision-making in global health. PMID:25766240

The NASA Ames Fatigue Countermeasures Program: The Next Generation

NASA Technical Reports Server (NTRS)

Rosekind, Mark R.; Neri, David F.; Miller, Donna L.; Gregory, Kevin B.; Webbon, Lissa L.; Oyung, Ray L.

1997-01-01

Twenty-four hour, global aviation operations pose unique challenges to humans. Physiological requirements related to sleep, the internal circadian clock, and human fatigue are critical factors that are known to affect safety, performance, and productivity. Understanding the human operators' physiological capabilities, and limitations, will be important to address these issues as global demand for aviation activities continues to increase. In 1980, in response to a Congressional request, the National Aeronautics and Space Administration (NASA) Ames Research Center initiated a Fatigue/Jet Lag Program to examine the role of fatigue in flight operations. Originally established by Dr. John K. Lauber and Dr. Charles E. Billings, the Program was designed to address three objectives: (1) determine the extent of fatigue, sleep loss, and circadian disruption in flight operations; (2) determine how fatigue affected flight crew performance; and (3) develop strategies to maximize performance and alertness during flight operations.

Does leptin cause an increase in blood pressure in animals and humans?

PubMed

Simonds, Stephanie E; Pryor, Jack T; Cowley, Michael A

2017-01-01

Cardiovascular diseases (CVDs) are the number one cause of death globally. The risk for the development of CVDs is significantly increased in obesity. Leptin, the product of white adipose tissue, appears to contribute to the development of CVDs in obesity. Here, we discuss the premise that leptin engages the sympathetic nervous system and contributes to elevated blood pressure (BP) developing in obesity. The long-term regulation of BP is dependent on the activity of the autonomic nervous system and specifically the sympathetic nervous system. Sympathetic nerve activity is significantly increased in obese rodents and humans. Leptin increases sympathetic nerve activity in rodents and humans; however, leptin only consistently increases BP chronically in rodents. The ability of leptin to increase BP in rodents is via both hypothalamic and extrahypothalamic regions. In leptin-deficient and leptin receptor-deficient humans, leptin appears to be the key reason for decreased systolic BP. However, in other research conducted in humans, chronic administration of leptin does not elevate BP. Further research into the role of leptin in the development of CVDs, especially in humans, needs to be conducted.

Modulators of mercury risk to wildlife and humans in the context of rapid global change

USGS Publications Warehouse

Eagles-Smith, Collin A.; Silbergeld, Ellen K.; Basu, Niladri; Bustamante, Paco; Diaz-Barriga, Fernando; Hopkins, William A.; Kidd, Karen A.; Nyland, Jennifer F.

2018-01-01

Environmental mercury (Hg) contamination is an urgent global health threat. The complexity of Hg in the environment can hinder accurate determination of ecological and human health risks, particularly within the context of the rapid global changes that are altering many ecological processes, socioeconomic patterns, and other factors like infectious disease incidence, which can affect Hg exposures and health outcomes. However, the success of global Hg-reduction efforts depends on accurate assessments of their effectiveness in reducing health risks. In this paper, we examine the role that key extrinsic and intrinsic drivers play on several aspects of Hg risk to humans and organisms in the environment. We do so within three key domains of ecological and human health risk. First, we examine how extrinsic global change drivers influence pathways of Hg bioaccumulation and biomagnification through food webs. Next, we describe how extrinsic socioeconomic drivers at a global scale, and intrinsic individual-level drivers, influence human Hg exposure. Finally, we address how the adverse health effects of Hg in humans and wildlife are modulated by a range of extrinsic and intrinsic drivers within the context of rapid global change. Incorporating components of these three domains into research and monitoring will facilitate a more holistic understanding of how ecological and societal drivers interact to influence Hg health risks.

Global climate change: the quantifiable sustainability challenge.

PubMed

Princiotta, Frank T; Loughlin, Daniel H

2014-09-01

Population growth and the pressures spawned by increasing demands for energy and resource-intensive goods, foods, and services are driving unsustainable growth in greenhouse gas (GHG) emissions. Recent GHG emission trends are consistent with worst-case scenarios of the previous decade. Dramatic and near-term emission reductions likely will be needed to ameliorate the potential deleterious impacts of climate change. To achieve such reductions, fundamental changes are required in the way that energy is generated and used. New technologies must be developed and deployed at a rapid rate. Advances in carbon capture and storage, renewable, nuclear and transportation technologies are particularly important; however, global research and development efforts related to these technologies currently appear to fall short relative to needs. Even with a proactive and international mitigation effort, humanity will need to adapt to climate change, but the adaptation needs and damages will be far greater if mitigation activities are not pursued in earnest. In this review, research is highlighted that indicates increasing global and regional temperatures and ties climate changes to increasing GHG emissions. GHG mitigation targets necessary for limiting future global temperature increases are discussed, including how factors such as population growth and the growing energy intensity of the developing world will make these reduction targets more challenging. Potential technological pathways for meeting emission reduction targets are examined, barriers are discussed, and global and US. modeling results are presented that suggest that the necessary pathways will require radically transformed electric and mobile sectors. While geoengineering options have been proposed to allow more time for serious emission reductions, these measures are at the conceptual stage with many unanswered cost, environmental, and political issues. Implications: This paper lays out the case that mitigating the potential for catastrophic climate change will be a monumental challenge, requiring the global community to transform its energy system in an aggressive, coordinated, and timely manner. If this challenge is to be met, new technologies will have to be developed and deployed at a rapid rate. Advances in carbon capture and storage, renewable, nuclear, and transportation technologies are particularly important. Even with an aggressive international mitigation effort, humanity will still need to adapt to significant climate change.

From Early Child Development to Human Development: Investing in Our Children's Future. Proceedings of a World Bank Conference (Washington, D.C., April 10-11, 2000).

ERIC Educational Resources Information Center

Young, Mary Eming, Ed.

In April 2000, the World Bank hosted a global conference that addressed the benefits and challenges of investing in early child development (ECD). The landmark conference brought together the world's leading experts, academicians, practitioners, and policymakers to focus on various aspects of ECD. This volume contains the proceedings of the…

A Cross-Cultural Perspective about the Implementation and Adaptation Process of the Schoolwide Enrichment Model: The Importance of Talent Development in a Global World

ERIC Educational Resources Information Center

Hernández-Torrano, Daniel; Saranli, Adile Gulsah

2015-01-01

Gifted education and talent development are considered today as key elements for developing human capital and increasing competitiveness within education and the economy. Within this framework, a growing number of countries have begun to invest large amounts of resources to discover and nurture their most able students. As boundaries and…

Programme on Education and Training.

ERIC Educational Resources Information Center

United Nations Univ., Tokyo (Japan).

The proposed educational policy and program of the United Nations University are described. The university's purpose is to provide innovative educational activities appropriate to "pressing global problems of human survival, development and welfare," in accordance with the university charter. Education and research are undertaken…

Reproductive tourism and the quest for global gender justice.

PubMed

Donchin, Anne

2010-09-01

Reproductive tourism is a manifestation of a larger, more inclusive trend toward globalization of capitalist cultural and material economies. This paper discusses the development of cross-border assisted reproduction within the globalized economy, transnational and local structural processes that influence the trade, social relations intersecting it, and implications for the healthcare systems affected. I focus on prevailing gender structures embedded in the cross-border trade and their intersection with other social and economic structures that reflect and impact globalization. I apply a social connection model of responsibility for unjust outcomes and consider strategies to counter structural injustices embedded in this industry. The concluding section discusses policy reforms and proposals for collaborative action to preclude further injustices and extend full human rights to all.

Sci-Fri AM: Quality, Safety, and Professional Issues 07: Global Medical Physics Efforts: Closing the Gap

DOE Office of Scientific and Technical Information (OSTI.GOV)

Van Dyk, Jacob

Purpose: There is an increasing awareness of the disparity in Medical Physics needs between high income countries (HICs) and low-to-middle income countries (LMICs). This is especially evident with the growing incidence of cancer in LMICs. Projections from the recent Lancet Oncology Commission on Expanding Global Access to Radiotherapy indicate that an additional 22,000 Medical Physicists will be required by 2035 to provide uniform access to radiation therapy globally. This paper addresses possibilities and challenges associated with closing the Medical Physics gap between HICs and LMICs. Methods: Medical Physics and Oncology related organizations involved in providing support to enhance cancer therapymore » in LMICs were reviewed, especially as related to education, training and human resource development. Results: More than 35 organizations involved in addressing the cancer crisis in LMICs were found. Of these, 16 involve Medical Physics activities, with 7 being specific Medical Physics-related organizations. Ten of the 16 are involved in some LMIC activities with 6 having a major emphasis on LMIC contexts. Conclusions: The development of Medical Physics human resource capacity is a major challenge for LMICs. Fifty-five countries have no radiation therapy capabilities and by implication no capacity to train Medical Physicists. Overt attention with structured and altruistic actions by HIC contexts will help make inroads into the LMIC needs. Clear options throughout career structures in support of global health considerations combined with strong partnerships between interested parties in HICs and LMICs will enhance the development of safe and resource-appropriate strategies for advancing Medical Physics capabilities.« less

Girls' Education, Development and Social Change: "Seeding, Strengthening and Linking" (Global Fund for Women)

ERIC Educational Resources Information Center

Porter, Shirley Anne

2016-01-01

This literature review will trace the recent history of the globalisation of human rights with reference to education, particularly for girls and women, but also looking more broadly to include education for boys and men. The main paradigms--traditional, neo-liberalism and philanthrocapitalism--for providing education in developing countries will…

The Culture Integration in The Context of National Art Schools--Prioritized Direction of Development of the Modern Humanities

ERIC Educational Resources Information Center

Melekhova, Ksenia Alexandrovna; Lichman, Yelena Yurievna

2016-01-01

The modern picture of the world is experiencing a permanent transformation, adapting to the influence of various globalization factors, the dominance of information technology, dynamic development of a material environment, etc. In these circumstances, the society faces a problem of a technocratic knowledge domination without attention to…

A Living Systems Model for Assessing and Promoting the Sustainability of Communities.

ERIC Educational Resources Information Center

Larrick, Steve

A living systems model of community development has been synthesized from elements of three perspectives: (1) a global movement toward more sustainable patterns of human development that is identifying indicators of community health in a wide range of categories; (2) research on the complex interactions of living systems that make life on earth…

An Empirical Study on Context Awareness Integrated Mobile Assisted Instruction and the Factors

ERIC Educational Resources Information Center

Zheng, Qiujin; Chen, Ting; Kong, Deyi

2017-01-01

Education is now an indicator of national modernization that countries in the world intend to promote the national quality and cultivate talents for national development through education. Especially, when human societies get into the 21st century, global societies, politics, economy, and culture are facing major changes. With the development of…

Think Piece: Cognitive Justice and Integration without Duress. The Future of Development Education--Perspectives from the South

ERIC Educational Resources Information Center

Odora Hoppers, Catherine A.

2015-01-01

"In a time of unacceptable global injustice, growing inequalities in the distribution of power, accelerating climate change, and unwavering racism and social exclusion, we are today facing the biggest challenges of human history" (European Conference on Intercultural Dialogue in Development Education, 2008: 1). A favourable wind is…

Social Change and Individual Change--Developmental Science as Guide Post

ERIC Educational Resources Information Center

Silbereisen, Rainer K.

2012-01-01

From a biopsychosocial perspective on human development, this essay review introduces a model linking social changes at the macro level with individual development at the micro level. German unification and the globalization of economy that followed are taken as a case in point for social changes that have affected the lives of many. It is argued…

Isotope studies in large river basins: A new global research focus

NASA Astrophysics Data System (ADS)

Gibson, John J.; Aggarwal, Pradeep; Hogan, James; Kendall, Carol; Martinelli, Luiz A.; Stichler, Willi; Rank, Dieter; Goni, Ibrahim; Choudhry, Manzoor; Gat, Joel; Bhattacharya, Sourendra; Sugimoto, Atsuko; Fekete, Balazs; Pietroniro, Alain; Maurer, Thomas; Panarello, Hector; Stone, David; Seyler, Patrick; Maurice-Bourgoin, Laurence; Herczeg, Andrew

Rivers are an important linkage in the global hydrological cycle, returning about 35%of continental precipitation to the oceans. Rivers are also the most important source of water for human use. Much of the world's population lives along large rivers, relying on them for trade, transportation, industry, agriculture, and domestic water supplies. The resulting pressure has led to the extreme regulation of some river systems, and often a degradation of water quantity and quality For sustainable management of water supply agriculture, flood-drought cycles, and ecosystem and human health, there is a basic need for improving the scientific understanding of water cycling processes in river basins, and the ability to detect and predict impacts of climate change and water resources development.

Reprogramming human gallbladder cells into insulin-producing β-like cells

PubMed Central

Benedetti, Eric; Wang, Yuhan; Pelz, Carl; Schug, Jonathan; Kaestner, Klaus H.; Grompe, Markus

2017-01-01

The gallbladder and cystic duct (GBCs) are parts of the extrahepatic biliary tree and share a common developmental origin with the ventral pancreas. Here, we report on the very first genetic reprogramming of patient-derived human GBCs to β-like cells for potential autologous cell replacement therapy for type 1 diabetes. We developed a robust method for large-scale expansion of human GBCs ex vivo. GBCs were reprogrammed into insulin-producing pancreatic β-like cells by a combined adenoviral-mediated expression of hallmark pancreatic endocrine transcription factors PDX1, MAFA, NEUROG3, and PAX6 and differentiation culture in vitro. The reprogrammed GBCs (rGBCs) strongly induced the production of insulin and pancreatic endocrine genes and these responded to glucose stimulation in vitro. rGBCs also expressed an islet-specific surface marker, which was used to enrich for the most highly reprogrammed cells. More importantly, global mRNA and microRNA expression profiles and protein immunostaining indicated that rGBCs adopted an overall β-like state and these rGBCs engrafted in immunodeficient mice. Furthermore, comparative global expression analyses identified putative regulators of human biliary to β cell fate conversion. In summary, we have developed, for the first time, a reliable and robust genetic reprogramming and culture expansion of primary human GBCs—derived from multiple unrelated donors—into pancreatic β-like cells ex vivo, thus showing that human gallbladder is a potentially rich source of reprogrammable cells for autologous cell therapy in diabetes. PMID:28813430

Global Exploration Roadmap Derived Concept for Human Exploration of the Moon

NASA Technical Reports Server (NTRS)

Whitley, Ryan; Landgraf, Markus; Sato, Naoki; Picard, Martin; Goodliff, Kandyce; Stephenson, Keith; Narita, Shinichiro; Gonthier, Yves; Cowley, Aiden; Hosseini, Shahrzad;

Sacred Values, Strategic Communication, and Military Operations in Afghanistan

DTIC Science & Technology

2010-02-17

remembrance afterward is nothing less than a people‟s mass. War is the liturgy of identity.” Michael Vlahos 20 Combatant commanders (COCOMs) require...development. Identify Formation: Michael Vlahos ―…maintains that the process of globalization ushered into human consciousness a crisis of human change...provide contexts for the clash of political will. Conflict provides stories, symbols, and rituals that create narratives and form identity. Vlahos

Trends in Global Nutrition Policy and Implications for Japanese Development Policy.

PubMed

Nomura, Marika; Takahashi, Kenzo; Reich, Michael R

2015-12-01

Although the issue of nutrition was long underrepresented in the global health agenda, it regained international attention with the introduction of the Scaling Up Nutrition (SUN) framework. A historical review of global nutrition policies over 4 decades illustrates the evolution of nutrition policy themes and the challenges confronted by SUN. This study reviews major events in global nutrition policy from the 1970s to the SUN movement around 2010 to illustrate the dynamics of global agenda setting for nutrition policy along with implications for the government of Japan. The events are categorized according to each decade's nutrition paradigm: nutrition and its socioeconomic features in the 1970s, nutrition and community programs in the 1980s, nutrition as a political issue in the 1990s, and nutrition and evidence in the 2000s. This study identified 2 findings: First, the arguments that led to a global consensus on nutrition policy generated paradigm shifts in core ideas, and second, in response to these paradigm shifts, global nutrition policies have changed significantly over time. With regard to Japan, this analysis concludes that the government of Japan can take a greater initiative in the global health community as supporter of SUN by strategically developing a combination of financial, political, and practical approaches to improve global nutrition policy through the concepts of Universal Health Coverage and Human Security. © The Author(s) 2015.