Sample records for gold standard equipment

  1. Establishment of gold-quartz standard GQS-1

    USGS Publications Warehouse

    Millard, Hugh T.; Marinenko, John; McLane, John E.

    1969-01-01

    A homogeneous gold-quartz standard, GQS-1, was prepared from a heterogeneous gold-bearing quartz by chemical treatment. The concentration of gold in GQS-1 was determined by both instrumental neutron activation analysis and radioisotope dilution analysis to be 2.61?0.10 parts per million. Analysis of 10 samples of the standard by both instrumental neutron activation analysis and radioisotope dilution analysis failed to reveal heterogeneity within the standard. The precision of the analytical methods, expressed as standard error, was approximately 0.1 part per million. The analytical data were also used to estimate the average size of gold particles. The chemical treatment apparently reduced the average diameter of the gold particles by at least an order of magnitude and increased the concentration of gold grains by a factor of at least 4,000.

  2. The best choice of equipment to obtain high quality standardised results in intra-oral photography - a comparison between the common practice in the UK and the gold standard set by the literature.

    PubMed

    Marcato, Laura; Sandler, Jonathan

    2018-04-01

    Since digital technology made dental photography widely available, photographers have been trying to establish the 'gold standard' when obtaining intra-oral photographs. A basic knowledge of photographic principles, familiarity with particular dental techniques and a correct choice and use of equipment contribute significantly both to the standardisation and quality of photographs. A recent survey between members of the Institute of Medical Illustrators shed a light on the current practice in the UK. Medical photographers do not always have access to the full range of suitable equipment. A better selection of retractors and occlusal mirrors would undoubtedly contribute to higher quality images.

  3. Advocacy: Making the Gold Standard School a Reality

    ERIC Educational Resources Information Center

    Roberts, Julia Link; Inman, Tracy Ford

    2011-01-01

    In their last column, the authors described a Gold Standard School--a place in which all children thrive including the gifted and talented. The Checklist for a Gold Standard School, which is included in this article, highlights the main characteristics of such a school including a focus on continuous progress, talent development, policies that…

  4. Equipment Standards: History, Litigation, and Advice

    PubMed Central

    Hedley-Whyte, John; Milamed, Debra R.

    1999-01-01

    Summary The authors present a concise history of the development of national and international standards for surgical equipment. Standards-writing organizations, surgical and other specialty societies, universities, test houses, and the U.S. government have influenced this process, which is now manifested in complex interactions between national and international standards-writing organizations, and in CE (Conformité Europeene) marks being placed on surgical equipment in the United States and elsewhere. The history of litigation in standards development is also reviewed. Recommendations to maximize patient safety and to help ensure successful, cost-effective defense in litigation for surgeons who use equipment and may suffer its malfunctions are given. Overall, the complicated oversight of surgical equipment standards and the approval process appears to be contributing to the improving and outstanding results of U.S. surgery reported by the U.S. government. PMID:10400045

  5. 40 CFR 63.691 - Standards: Equipment leaks.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 10 2010-07-01 2010-07-01 false Standards: Equipment leaks. 63.691....691 Standards: Equipment leaks. (a) The provisions of this section apply to the control of air emissions from equipment leaks for which § 63.683(d) references the use of this section for such air...

  6. Imperfect Gold Standards for Kidney Injury Biomarker Evaluation

    PubMed Central

    Betensky, Rebecca A.; Emerson, Sarah C.; Bonventre, Joseph V.

    2012-01-01

    Clinicians have used serum creatinine in diagnostic testing for acute kidney injury for decades, despite its imperfect sensitivity and specificity. Novel tubular injury biomarkers may revolutionize the diagnosis of acute kidney injury; however, even if a novel tubular injury biomarker is 100% sensitive and 100% specific, it may appear inaccurate when using serum creatinine as the gold standard. Acute kidney injury, as defined by serum creatinine, may not reflect tubular injury, and the absence of changes in serum creatinine does not assure the absence of tubular injury. In general, the apparent diagnostic performance of a biomarker depends not only on its ability to detect injury, but also on disease prevalence and the sensitivity and specificity of the imperfect gold standard. Assuming that, at a certain cutoff value, serum creatinine is 80% sensitive and 90% specific and disease prevalence is 10%, a new perfect biomarker with a true 100% sensitivity may seem to have only 47% sensitivity compared with serum creatinine as the gold standard. Minimizing misclassification by using more strict criteria to diagnose acute kidney injury will reduce the error when evaluating the performance of a biomarker under investigation. Apparent diagnostic errors using a new biomarker may be a reflection of errors in the imperfect gold standard itself, rather than poor performance of the biomarker. The results of this study suggest that small changes in serum creatinine alone should not be used to define acute kidney injury in biomarker or interventional studies. PMID:22021710

  7. 77 FR 14706 - Medical Diagnostic Equipment Accessibility Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-13

    ...-0003] RIN 3014-AA40 Medical Diagnostic Equipment Accessibility Standards AGENCY: Architectural and... for medical diagnostic equipment and issues raised in the public comments on the NPRM. The Access... accessibility standards for medical diagnostic equipment, in consultation with the Commissioner of the Food and...

  8. 40 CFR 63.424 - Standards: Equipment leaks.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 9 2010-07-01 2010-07-01 false Standards: Equipment leaks. 63.424....424 Standards: Equipment leaks. (a) Each owner or operator of a bulk gasoline terminal or pipeline breakout station subject to the provisions of this subpart shall perform a monthly leak inspection of all...

  9. 75 FR 35439 - Medical Diagnostic Equipment Accessibility Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-22

    ... ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD Medical Diagnostic Equipment... accessibility standards for medical diagnostic equipment to ensure that such equipment is accessible to, and... respect to medical diagnostic equipment and existing guidance for designing accessible medical diagnostic...

  10. 77 FR 62479 - Medical Diagnostic Equipment Accessibility Standards Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-15

    ...-0003] RIN 3014-AA40 Medical Diagnostic Equipment Accessibility Standards Advisory Committee AGENCY.... SUMMARY: The Medical Diagnostic Equipment Accessibility Standards Advisory Committee (Committee) will hold... Proposed Rulemaking (NPRM) on Medical Diagnostic Equipment Accessibility Standards. DATES: The Committee...

  11. 78 FR 10582 - Medical Diagnostic Equipment Accessibility Standards Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-14

    ...-0003] RIN 3014-AA40 Medical Diagnostic Equipment Accessibility Standards Advisory Committee AGENCY.... SUMMARY: The Medical Diagnostic Equipment Accessibility Standards Advisory Committee will hold its fourth...) on Medical Diagnostic Equipment Accessibility Standards. DATES: The Committee will meet on February...

  12. 78 FR 32612 - Medical Diagnostic Equipment Accessibility Standards Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-31

    ...-0003] RIN 3014-AA40 Medical Diagnostic Equipment Accessibility Standards Advisory Committee AGENCY.... SUMMARY: The Medical Diagnostic Equipment Accessibility Standards Advisory Committee will hold its seventh...) on Medical Diagnostic Equipment Accessibility Standards. DATES: The Committee will meet on June 17...

  13. 78 FR 1166 - Medical Diagnostic Equipment Accessibility Standards Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    ...-0003] RIN 3014-AA40 Medical Diagnostic Equipment Accessibility Standards Advisory Committee AGENCY.... SUMMARY: The Medical Diagnostic Equipment Accessibility Standards Advisory Committee will hold its third...) on Medical Diagnostic Equipment Accessibility Standards. DATES: The Committee will meet on January 22...

  14. 78 FR 23872 - Medical Diagnostic Equipment Accessibility Standards Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-23

    ...-0003] RIN 3014-AA40 Medical Diagnostic Equipment Accessibility Standards Advisory Committee AGENCY.... SUMMARY: The Medical Diagnostic Equipment Accessibility Standards Advisory Committee will hold its sixth...) on Medical Diagnostic Equipment Accessibility Standards. DATES: The Committee will meet on May 7...

  15. 78 FR 16448 - Medical Diagnostic Equipment Accessibility Standards Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-15

    ...-0003] RIN 3014-AA40 Medical Diagnostic Equipment Accessibility Standards Advisory Committee AGENCY.... SUMMARY: The Medical Diagnostic Equipment Accessibility Standards Advisory Committee will hold its fifth...) on Medical Diagnostic Equipment Accessibility Standards. DATES: The Committee will meet on March 26...

  16. On-line hemodiafiltration. Gold standard or top therapy?

    PubMed

    Passlick-Deetjen, Jutta; Pohlmeier, Robert

    2002-01-01

    In summary, on-line HDF is an extracorporeal blood purification therapy with increased convective removal of uremic toxins as compared to the most frequently used low- or high-flux HD therapy. The clinical advantages of on-line HDF have shown to be dose dependent, which makes on-line HDF superior to other therapies with less convective solute removal. Among the therapies with high convective solute removal, i.e. on-line HDF, on-line HF and double high-flux dialysis, it is difficult to finally decide on the best therapy, as direct comparisons of these therapies are not performed. Theoretical considerations like the relative to on-line HDF lower achievable Kt/Vurea with on-line HF, allow to state that on-line HDF is the top therapy now available for patients with ESRD. A gold standard may be defined as something with which everything else is compared if one tries to establish it in the respective field. In order to declare on-line HDF as the gold standard in renal replacement therapy, we need more direct comparisons of on-line HDF with other therapies, including mortality as an outcome parameter. However, based on our current knowledge, it does not seem to be too speculative that high-quality clinical studies will establish on-line HDF in the next years as the new gold standard in renal replacement therapy.

  17. 30 CFR 250.112 - What standards must my welding equipment meet?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false What standards must my welding equipment meet... Performance Standards § 250.112 What standards must my welding equipment meet? Your welding equipment must meet the following requirements: (a) All engine-driven welding equipment must be equipped with spark...

  18. 30 CFR 250.112 - What standards must my welding equipment meet?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false What standards must my welding equipment meet... Performance Standards § 250.112 What standards must my welding equipment meet? Your welding equipment must meet the following requirements: (a) All engine-driven welding equipment must be equipped with spark...

  19. 30 CFR 250.112 - What standards must my welding equipment meet?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false What standards must my welding equipment meet... Performance Standards § 250.112 What standards must my welding equipment meet? Your welding equipment must meet the following requirements: (a) All engine-driven welding equipment must be equipped with spark...

  20. 77 FR 39656 - Medical Diagnostic Equipment Accessibility Standards Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-05

    ...-0003] RIN 3014-AA40 Medical Diagnostic Equipment Accessibility Standards Advisory Committee AGENCY... Diagnostic Equipment Accessibility Standards. DATES: The first meeting of the committee will be held at a... Equipment Accessibility Standards. See 77 FR 14706 (March 13, 2012). Section 510 of the Rehabilitation Act...

  1. 77 FR 67595 - Medical Diagnostic Equipment Accessibility Standards Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-13

    ...-0003] RIN 3014-AA40 Medical Diagnostic Equipment Accessibility Standards Advisory Committee AGENCY.... SUMMARY: The Medical Diagnostic Equipment Accessibility Standards Advisory Committee (Committee) will hold... Equipment Accessibility Standards. DATES: The Committee will meet on December 3, 2012, from 10:00 a.m. to 5...

  2. Recovery of gold from waste electrical and electronic equipment (WEEE) using ammonium persulfate.

    PubMed

    Alzate, Andrea; López, Maria Esperanza; Serna, Claudia

    2016-11-01

    This paper presents a novel methodology to recover gold from waste electrical and electronic equipment (WEEE) using ammonium persulfate ((NH 4 ) 2 S 2 O 8 ). Gold was recovered as a fine coating using substrate oxidation without shredding or grinding process. The WEEE sample was characterized giving values of Au: 1.05g/kg, Fe: 86.00g/kg, Ni: 73.64g/kg, Cu: 26.65g/kg. The effect of (NH 4 ) 2 S 2 O 8 concentration (0.22-1.10M), oxygen (0.0-1.4L/min) and L/S ratio (10-30mL/g) on the main responses (substrate oxidation and Au recovery) was investigated implementing response surface methodology with numerical optimization. A quadratic model was developed and quantities greater than 98% of Au were recovered. The findings presented suggest that, optimized quantities of ammonium persulfate in aqueous highly oxygenated media could be used to extract superficial gold from WEEE. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. 41 CFR 109-38.5104 - Other motor equipment utilization standards.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Other motor equipment... AVIATION, TRANSPORTATION, AND MOTOR VEHICLES 38-MOTOR EQUIPMENT MANAGEMENT 38.51-Utilization of Motor Equipment § 109-38.5104 Other motor equipment utilization standards. No utilization standards are...

  4. 41 CFR 109-38.5104 - Other motor equipment utilization standards.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Other motor equipment... AVIATION, TRANSPORTATION, AND MOTOR VEHICLES 38-MOTOR EQUIPMENT MANAGEMENT 38.51-Utilization of Motor Equipment § 109-38.5104 Other motor equipment utilization standards. No utilization standards are...

  5. Leishmania infection: laboratory diagnosing in the absence of a "gold standard".

    PubMed

    Rodríguez-Cortés, Alhelí; Ojeda, Ana; Francino, Olga; López-Fuertes, Laura; Timón, Marcos; Alberola, Jordi

    2010-02-01

    There is no gold standard for diagnosing leishmaniases. Our aim was to assess the operative validity of tests used in detecting Leishmania infection using samples from experimental infections, a reliable equivalent to the classic definition of gold standard. Without statistical differences, the highest sensitivity was achieved by protein A (ProtA), immunoglobulin (Ig)G2, indirect fluorescenece antibody test (IFAT), lymphocyte proliferation assay, quantitative real-time polymerase chain reaction of bone marrow (qPCR-BM), qPCR-Blood, and IgG; and the highest specificity by IgG1, IgM, IgA, qPCR-Blood, IgG, IgG2, and qPCR-BM. Maximum positive predictive value was obtained simultaneously by IgG2, qPCR-Blood, and IgG; and maximum negative predictive value by qPCR-BM. Best positive and negative likelihood ratios were obtained by IgG2. The test having the greatest, statistically significant, area under the receiver operating characteristics curve was IgG2 enzyme-linked immunosorbent assay (ELISA). Thus, according to the gold standard used, IFAT and qPCR are far from fulfilling the requirements to be considered gold standards, and the test showing the highest potential to detect Leishmania infection is Leishmania-specific ELISA IgG2.

  6. A quantitative literature-curated gold standard for kinase-substrate pairs

    PubMed Central

    2011-01-01

    We describe the Yeast Kinase Interaction Database (KID, http://www.moseslab.csb.utoronto.ca/KID/), which contains high- and low-throughput data relevant to phosphorylation events. KID includes 6,225 low-throughput and 21,990 high-throughput interactions, from greater than 35,000 experiments. By quantitatively integrating these data, we identified 517 high-confidence kinase-substrate pairs that we consider a gold standard. We show that this gold standard can be used to assess published high-throughput datasets, suggesting that it will enable similar rigorous assessments in the future. PMID:21492431

  7. 14 CFR 23.1447 - Equipment standards for oxygen dispensing units.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Equipment standards for oxygen dispensing... Equipment Miscellaneous Equipment § 23.1447 Equipment standards for oxygen dispensing units. If oxygen... occupant for whom supplemental oxygen is to be supplied. Each dispensing unit must: (1) Provide for...

  8. 14 CFR 23.1447 - Equipment standards for oxygen dispensing units.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Equipment standards for oxygen dispensing... Equipment Miscellaneous Equipment § 23.1447 Equipment standards for oxygen dispensing units. If oxygen... occupant for whom supplemental oxygen is to be supplied. Each dispensing unit must: (1) Provide for...

  9. 14 CFR 23.1447 - Equipment standards for oxygen dispensing units.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Equipment standards for oxygen dispensing... Equipment Miscellaneous Equipment § 23.1447 Equipment standards for oxygen dispensing units. If oxygen... occupant for whom supplemental oxygen is to be supplied. Each dispensing unit must: (1) Provide for...

  10. 14 CFR 23.1447 - Equipment standards for oxygen dispensing units.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Equipment standards for oxygen dispensing... Equipment Miscellaneous Equipment § 23.1447 Equipment standards for oxygen dispensing units. If oxygen... occupant for whom supplemental oxygen is to be supplied. Each dispensing unit must: (1) Provide for...

  11. 14 CFR 23.1447 - Equipment standards for oxygen dispensing units.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Equipment standards for oxygen dispensing... Equipment Miscellaneous Equipment § 23.1447 Equipment standards for oxygen dispensing units. Link to an amendment published at 76 FR 75762, December 2, 2011. If oxygen dispensing units are installed, the...

  12. Interface standards for computer equipment

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The ability to configure data systems using modules provided by independent manufacturers is complicated by the wide range of electrical, mechanical, and functional characteristics exhibited within the equipment provided by different manufacturers of computers, peripherals, and terminal devices. A number of international organizations were and still are involved in the creation of standards that enable devices to be interconnected with minimal difficulty, usually involving only a cable or data bus connection that is defined by the standard. The elements covered by an interface standard are covered and the most prominent interface standards presently in use are identified and described.

  13. 30 CFR 250.112 - What standards must my welding equipment meet?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What standards must my welding equipment meet... SHELF General Performance Standards § 250.112 What standards must my welding equipment meet? Your welding equipment must meet the following requirements: (a) All engine-driven welding equipment must be...

  14. 77 FR 53163 - Medical Diagnostic Equipment Accessibility Standards Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-31

    ...-0003] RIN 3014-AA40 Medical Diagnostic Equipment Accessibility Standards Advisory Committee AGENCY.... SUMMARY: The Medical Diagnostic Equipment Accessibility Standards Advisory Committee (Committee) will hold... previously published Notice of Proposed Rulemaking (NPRM) on Medical Diagnostic Equipment Accessibility...

  15. 14 CFR 121.335 - Equipment standards.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Equipment standards. (a) Reciprocating engine powered airplanes. The oxygen apparatus, the minimum rates of oxygen flow, and the supply of oxygen necessary to comply with § 121.327 must meet the standards...) Turbine engine powered airplanes. The oxygen apparatus, the minimum rate of oxygen flow, and the supply of...

  16. 14 CFR 121.335 - Equipment standards.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Equipment standards. (a) Reciprocating engine powered airplanes. The oxygen apparatus, the minimum rates of oxygen flow, and the supply of oxygen necessary to comply with § 121.327 must meet the standards...) Turbine engine powered airplanes. The oxygen apparatus, the minimum rate of oxygen flow, and the supply of...

  17. 14 CFR 121.335 - Equipment standards.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Equipment standards. (a) Reciprocating engine powered airplanes. The oxygen apparatus, the minimum rates of oxygen flow, and the supply of oxygen necessary to comply with § 121.327 must meet the standards...) Turbine engine powered airplanes. The oxygen apparatus, the minimum rate of oxygen flow, and the supply of...

  18. 14 CFR 121.335 - Equipment standards.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Equipment standards. (a) Reciprocating engine powered airplanes. The oxygen apparatus, the minimum rates of oxygen flow, and the supply of oxygen necessary to comply with § 121.327 must meet the standards...) Turbine engine powered airplanes. The oxygen apparatus, the minimum rate of oxygen flow, and the supply of...

  19. 14 CFR 121.335 - Equipment standards.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Equipment standards. (a) Reciprocating engine powered airplanes. The oxygen apparatus, the minimum rates of oxygen flow, and the supply of oxygen necessary to comply with § 121.327 must meet the standards...) Turbine engine powered airplanes. The oxygen apparatus, the minimum rate of oxygen flow, and the supply of...

  20. 40 CFR 61.135 - Standard: Equipment leaks.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Section 61.135 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standard for Benzene Emissions from Coke By-Product Recovery Plants § 61.135 Standard: Equipment leaks. (a) Each owner or...

  1. 30 CFR 250.112 - What standards must my welding equipment meet?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What standards must my welding equipment meet... § 250.112 What standards must my welding equipment meet? Your welding equipment must meet the following requirements: (a) All engine-driven welding equipment must be equipped with spark arrestors and drip pans; (b...

  2. 40 CFR 61.135 - Standard: Equipment leaks.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Emissions from Coke By-Product Recovery Plants § 61.135 Standard: Equipment leaks. (a) Each owner or... benzene service. (d) Each exhauster shall be monitored quarterly to detect leaks by the methods specified... stuffing box pressure; or (ii) Equipped with a barrier fluid system that is connected by a closed vent...

  3. Methodological Pluralism: The Gold Standard of STEM Evaluation

    ERIC Educational Resources Information Center

    Lawrenz, Frances; Huffman, Douglas

    2006-01-01

    Nationally, there is continuing debate about appropriate methods for conducting educational evaluations. The U.S. Department of Education has placed a priority on "scientifically" based evaluation methods and has advocated a "gold standard" of randomized controlled experimentation. The priority suggests that randomized control methods are best,…

  4. 14 CFR 25.1447 - Equipment standards for oxygen dispensing units.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Equipment standards for oxygen dispensing... § 25.1447 Equipment standards for oxygen dispensing units. If oxygen dispensing units are installed... supplemental oxygen is to be supplied. Units must be designed to cover the nose and mouth and must be equipped...

  5. 14 CFR 25.1447 - Equipment standards for oxygen dispensing units.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Equipment standards for oxygen dispensing... § 25.1447 Equipment standards for oxygen dispensing units. If oxygen dispensing units are installed... supplemental oxygen is to be supplied. Units must be designed to cover the nose and mouth and must be equipped...

  6. 14 CFR 25.1447 - Equipment standards for oxygen dispensing units.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Equipment standards for oxygen dispensing... § 25.1447 Equipment standards for oxygen dispensing units. If oxygen dispensing units are installed... supplemental oxygen is to be supplied. Units must be designed to cover the nose and mouth and must be equipped...

  7. 14 CFR 25.1447 - Equipment standards for oxygen dispensing units.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Equipment standards for oxygen dispensing... § 25.1447 Equipment standards for oxygen dispensing units. If oxygen dispensing units are installed... supplemental oxygen is to be supplied. Units must be designed to cover the nose and mouth and must be equipped...

  8. 14 CFR 25.1447 - Equipment standards for oxygen dispensing units.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Equipment standards for oxygen dispensing... § 25.1447 Equipment standards for oxygen dispensing units. If oxygen dispensing units are installed... supplemental oxygen is to be supplied. Units must be designed to cover the nose and mouth and must be equipped...

  9. An ROC-type measure of diagnostic accuracy when the gold standard is continuous-scale.

    PubMed

    Obuchowski, Nancy A

    2006-02-15

    ROC curves and summary measures of accuracy derived from them, such as the area under the ROC curve, have become the standard for describing and comparing the accuracy of diagnostic tests. Methods for estimating ROC curves rely on the existence of a gold standard which dichotomizes patients into disease present or absent. There are, however, many examples of diagnostic tests whose gold standards are not binary-scale, but rather continuous-scale. Unnatural dichotomization of these gold standards leads to bias and inconsistency in estimates of diagnostic accuracy. In this paper, we propose a non-parametric estimator of diagnostic test accuracy which does not require dichotomization of the gold standard. This estimator has an interpretation analogous to the area under the ROC curve. We propose a confidence interval for test accuracy and a statistical test for comparing accuracies of tests from paired designs. We compare the performance (i.e. CI coverage, type I error rate, power) of the proposed methods with several alternatives. An example is presented where the accuracies of two quick blood tests for measuring serum iron concentrations are estimated and compared.

  10. A framework for automatic creation of gold-standard rigid 3D-2D registration datasets.

    PubMed

    Madan, Hennadii; Pernuš, Franjo; Likar, Boštjan; Špiclin, Žiga

    2017-02-01

    Advanced image-guided medical procedures incorporate 2D intra-interventional information into pre-interventional 3D image and plan of the procedure through 3D/2D image registration (32R). To enter clinical use, and even for publication purposes, novel and existing 32R methods have to be rigorously validated. The performance of a 32R method can be estimated by comparing it to an accurate reference or gold standard method (usually based on fiducial markers) on the same set of images (gold standard dataset). Objective validation and comparison of methods are possible only if evaluation methodology is standardized, and the gold standard  dataset is made publicly available. Currently, very few such datasets exist and only one contains images of multiple patients acquired during a procedure. To encourage the creation of gold standard 32R datasets, we propose an automatic framework. The framework is based on rigid registration of fiducial markers. The main novelty is spatial grouping of fiducial markers on the carrier device, which enables automatic marker localization and identification across the 3D and 2D images. The proposed framework was demonstrated on clinical angiograms of 20 patients. Rigid 32R computed by the framework was more accurate than that obtained manually, with the respective target registration error below 0.027 mm compared to 0.040 mm. The framework is applicable for gold standard setup on any rigid anatomy, provided that the acquired images contain spatially grouped fiducial markers. The gold standard datasets and software will be made publicly available.

  11. Integrated Personal Protective Equipment Standards Support Model

    DTIC Science & Technology

    2008-04-01

    traditional SCBA showed that the distribution of the weight is important as well. Twelve firefighters performed simulated fire -fighting and rescue exercises...respiratory equipment standards and five National Fire Protection Association (NFPA) protective suit, clothing, and respirator standards. The...respirators. The clothing standards were for protective ensembles for urban search and rescue operations, open circuit SCBA for fire and emergency

  12. Task-based evaluation of segmentation algorithms for diffusion-weighted MRI without using a gold standard

    PubMed Central

    Jha, Abhinav K.; Kupinski, Matthew A.; Rodríguez, Jeffrey J.; Stephen, Renu M.; Stopeck, Alison T.

    2012-01-01

    In many studies, the estimation of the apparent diffusion coefficient (ADC) of lesions in visceral organs in diffusion-weighted (DW) magnetic resonance images requires an accurate lesion-segmentation algorithm. To evaluate these lesion-segmentation algorithms, region-overlap measures are used currently. However, the end task from the DW images is accurate ADC estimation, and the region-overlap measures do not evaluate the segmentation algorithms on this task. Moreover, these measures rely on the existence of gold-standard segmentation of the lesion, which is typically unavailable. In this paper, we study the problem of task-based evaluation of segmentation algorithms in DW imaging in the absence of a gold standard. We first show that using manual segmentations instead of gold-standard segmentations for this task-based evaluation is unreliable. We then propose a method to compare the segmentation algorithms that does not require gold-standard or manual segmentation results. The no-gold-standard method estimates the bias and the variance of the error between the true ADC values and the ADC values estimated using the automated segmentation algorithm. The method can be used to rank the segmentation algorithms on the basis of both accuracy and precision. We also propose consistency checks for this evaluation technique. PMID:22713231

  13. 14 CFR 25.1445 - Equipment standards for the oxygen distributing system.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Equipment standards for the oxygen... Miscellaneous Equipment § 25.1445 Equipment standards for the oxygen distributing system. (a) When oxygen is... crew on duty. (b) Portable walk-around oxygen units of the continuous flow, diluter-demand, and...

  14. 14 CFR 25.1445 - Equipment standards for the oxygen distributing system.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Equipment standards for the oxygen... Miscellaneous Equipment § 25.1445 Equipment standards for the oxygen distributing system. (a) When oxygen is... crew on duty. (b) Portable walk-around oxygen units of the continuous flow, diluter-demand, and...

  15. 14 CFR 25.1445 - Equipment standards for the oxygen distributing system.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Equipment standards for the oxygen... Miscellaneous Equipment § 25.1445 Equipment standards for the oxygen distributing system. (a) When oxygen is... crew on duty. (b) Portable walk-around oxygen units of the continuous flow, diluter-demand, and...

  16. 14 CFR 25.1445 - Equipment standards for the oxygen distributing system.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Equipment standards for the oxygen... Miscellaneous Equipment § 25.1445 Equipment standards for the oxygen distributing system. (a) When oxygen is... crew on duty. (b) Portable walk-around oxygen units of the continuous flow, diluter-demand, and...

  17. 14 CFR 25.1445 - Equipment standards for the oxygen distributing system.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Equipment standards for the oxygen... Miscellaneous Equipment § 25.1445 Equipment standards for the oxygen distributing system. (a) When oxygen is... crew on duty. (b) Portable walk-around oxygen units of the continuous flow, diluter-demand, and...

  18. 77 FR 9859 - Lifesaving Equipment: Production Testing and Harmonization With International Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-21

    ... inflatable buoyant apparatuses may be certified using either occupant weight standard. Likewise, equipment...-AB46 Lifesaving Equipment: Production Testing and Harmonization With International Standards AGENCY... lifesaving equipment to harmonize Coast Guard regulations for inflatable liferafts and inflatable buoyant...

  19. Status of pre-processing of waste electrical and electronic equipment in Germany and its influence on the recovery of gold.

    PubMed

    Chancerel, Perrine; Bolland, Til; Rotter, Vera Susanne

    2011-03-01

    Waste electrical and electronic equipment (WEEE) contains gold in low but from an environmental and economic point of view relevant concentration. After collection, WEEE is pre-processed in order to generate appropriate material fractions that are sent to the subsequent end-processing stages (recovery, reuse or disposal). The goal of this research is to quantify the overall recovery rates of pre-processing technologies used in Germany for the reference year 2007. To achieve this goal, facilities operating in Germany were listed and classified according to the technology they apply. Information on their processing capacity was gathered by evaluating statistical databases. Based on a literature review of experimental results for gold recovery rates of different pre-processing technologies, the German overall recovery rate of gold at the pre-processing level was quantified depending on the characteristics of the treated WEEE. The results reveal that - depending on the equipment groups - pre-processing recovery rates of gold of 29 to 61% are achieved in Germany. Some practical recommendations to reduce the losses during pre-processing could be formulated. Defining mass-based recovery targets in the legislation does not set incentives to recover trace elements. Instead, the priorities for recycling could be defined based on other parameters like the environmental impacts of the materials. The implementation of measures to reduce the gold losses would also improve the recovery of several other non-ferrous metals like tin, nickel, and palladium.

  20. Gold-standard for computer-assisted morphological sperm analysis.

    PubMed

    Chang, Violeta; Garcia, Alejandra; Hitschfeld, Nancy; Härtel, Steffen

    2017-04-01

    Published algorithms for classification of human sperm heads are based on relatively small image databases that are not open to the public, and thus no direct comparison is available for competing methods. We describe a gold-standard for morphological sperm analysis (SCIAN-MorphoSpermGS), a dataset of sperm head images with expert-classification labels in one of the following classes: normal, tapered, pyriform, small or amorphous. This gold-standard is for evaluating and comparing known techniques and future improvements to present approaches for classification of human sperm heads for semen analysis. Although this paper does not provide a computational tool for morphological sperm analysis, we present a set of experiments for comparing sperm head description and classification common techniques. This classification base-line is aimed to be used as a reference for future improvements to present approaches for human sperm head classification. The gold-standard provides a label for each sperm head, which is achieved by majority voting among experts. The classification base-line compares four supervised learning methods (1- Nearest Neighbor, naive Bayes, decision trees and Support Vector Machine (SVM)) and three shape-based descriptors (Hu moments, Zernike moments and Fourier descriptors), reporting the accuracy and the true positive rate for each experiment. We used Fleiss' Kappa Coefficient to evaluate the inter-expert agreement and Fisher's exact test for inter-expert variability and statistical significant differences between descriptors and learning techniques. Our results confirm the high degree of inter-expert variability in the morphological sperm analysis. Regarding the classification base line, we show that none of the standard descriptors or classification approaches is best suitable for tackling the problem of sperm head classification. We discovered that the correct classification rate was highly variable when trying to discriminate among non-normal sperm

  1. Inspecting Cases against Revans' "Gold Standard" of Action Learning

    ERIC Educational Resources Information Center

    Willis, Verna J.

    2004-01-01

    A purposive sampling and analysis of ten case histories of action learning in the US suggests that applications tend to be partial, hierarchical, and leader controlled, thus running counter in several significant ways to the gold standard of Revans' action learning theory and egalitarian rules of engagement. Using critical markers to inspect the…

  2. 19 CFR 12.85 - Coast Guard boat and associated equipment safety standards.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false Coast Guard boat and associated equipment safety... SECURITY; DEPARTMENT OF THE TREASURY SPECIAL CLASSES OF MERCHANDISE Safety Standards for Boats and Associated Equipment § 12.85 Coast Guard boat and associated equipment safety standards. (a) Applicability of...

  3. 19 CFR 12.85 - Coast Guard boat and associated equipment safety standards.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false Coast Guard boat and associated equipment safety... SECURITY; DEPARTMENT OF THE TREASURY SPECIAL CLASSES OF MERCHANDISE Safety Standards for Boats and Associated Equipment § 12.85 Coast Guard boat and associated equipment safety standards. (a) Applicability of...

  4. 19 CFR 12.85 - Coast Guard boat and associated equipment safety standards.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false Coast Guard boat and associated equipment safety... SECURITY; DEPARTMENT OF THE TREASURY SPECIAL CLASSES OF MERCHANDISE Safety Standards for Boats and Associated Equipment § 12.85 Coast Guard boat and associated equipment safety standards. (a) Applicability of...

  5. 19 CFR 12.85 - Coast Guard boat and associated equipment safety standards.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Coast Guard boat and associated equipment safety... SECURITY; DEPARTMENT OF THE TREASURY SPECIAL CLASSES OF MERCHANDISE Safety Standards for Boats and Associated Equipment § 12.85 Coast Guard boat and associated equipment safety standards. (a) Applicability of...

  6. 19 CFR 12.85 - Coast Guard boat and associated equipment safety standards.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Coast Guard boat and associated equipment safety... SECURITY; DEPARTMENT OF THE TREASURY SPECIAL CLASSES OF MERCHANDISE Safety Standards for Boats and Associated Equipment § 12.85 Coast Guard boat and associated equipment safety standards. (a) Applicability of...

  7. The Trouble with the Gold Standard: School Libraries & Research

    ERIC Educational Resources Information Center

    Gordon, Carol

    2007-01-01

    Although science has provided empirical evidence for centuries, it's only as recently as the 1940s that a scientific method called randomized controlled trials (RCT) emerged as a technique to test the efficacy of drugs and medical procedures. Since RCT is unique in that it can claim causality, it's considered the "gold standard" of research…

  8. Seeking a valid gold standard for an innovative, dialect-neutral language test.

    PubMed

    Pearson, Barbara Zurer; Jackson, Janice E; Wu, Haotian

    2014-04-01

    PURPOSE In this study, the authors explored alternative gold standards to validate an innovative, dialect-neutral language assessment. METHOD Participants were 78 African American children, ages 5;0 (years;months) to 6;11. Twenty participants had previously been identified as having language impairment. The Diagnostic Evaluation of Language Variation-Norm Referenced (DELV-NR; Seymour, Roeper, & J. de Villiers, 2005) was administered, and concurrent language samples (LSs) were collected. Using LS profiles as the gold standard, sensitivity, specificity, and other measures of diagnostic accuracy were compared for diagnoses made from the DELV-NR and participants' clinical status prior to recruitment. In a second analysis, the authors used results from the first analysis to make evidence-based adjustments in the estimates of DELV-NR diagnostic accuracy. RESULTS Accuracy of the DELV-NR relative to LS profiles was greater than that of prior diagnoses, indicating that the DELV-NR was an improvement over preexisting diagnoses for this group. Specificity met conventional standards, but sensitivity was somewhat low. Reanalysis using the positive and negative predictive power of the preexisting diagnosis in a discrepant-resolution procedure revealed that estimates for sensitivity and specificity for the DELV-NR were .85 and .93, respectively. CONCLUSION The authors found that, even after making allowances for the imperfection of available gold standards, clinical decisions made with the DELV-NR achieved high values on conventional measures of diagnostic accuracy.

  9. A multilingual gold-standard corpus for biomedical concept recognition: the Mantra GSC

    PubMed Central

    Clematide, Simon; Akhondi, Saber A; van Mulligen, Erik M; Rebholz-Schuhmann, Dietrich

    2015-01-01

    Objective To create a multilingual gold-standard corpus for biomedical concept recognition. Materials and methods We selected text units from different parallel corpora (Medline abstract titles, drug labels, biomedical patent claims) in English, French, German, Spanish, and Dutch. Three annotators per language independently annotated the biomedical concepts, based on a subset of the Unified Medical Language System and covering a wide range of semantic groups. To reduce the annotation workload, automatically generated preannotations were provided. Individual annotations were automatically harmonized and then adjudicated, and cross-language consistency checks were carried out to arrive at the final annotations. Results The number of final annotations was 5530. Inter-annotator agreement scores indicate good agreement (median F-score 0.79), and are similar to those between individual annotators and the gold standard. The automatically generated harmonized annotation set for each language performed equally well as the best annotator for that language. Discussion The use of automatic preannotations, harmonized annotations, and parallel corpora helped to keep the manual annotation efforts manageable. The inter-annotator agreement scores provide a reference standard for gauging the performance of automatic annotation techniques. Conclusion To our knowledge, this is the first gold-standard corpus for biomedical concept recognition in languages other than English. Other distinguishing features are the wide variety of semantic groups that are being covered, and the diversity of text genres that were annotated. PMID:25948699

  10. Building a gold standard to construct search filters: a case study with biomarkers for oral cancer.

    PubMed

    Frazier, John J; Stein, Corey D; Tseytlin, Eugene; Bekhuis, Tanja

    2015-01-01

    To support clinical researchers, librarians and informationists may need search filters for particular tasks. Development of filters typically depends on a "gold standard" dataset. This paper describes generalizable methods for creating a gold standard to support future filter development and evaluation using oral squamous cell carcinoma (OSCC) as a case study. OSCC is the most common malignancy affecting the oral cavity. Investigation of biomarkers with potential prognostic utility is an active area of research in OSCC. The methods discussed here should be useful for designing quality search filters in similar domains. The authors searched MEDLINE for prognostic studies of OSCC, developed annotation guidelines for screeners, ran three calibration trials before annotating the remaining body of citations, and measured inter-annotator agreement (IAA). We retrieved 1,818 citations. After calibration, we screened the remaining citations (n = 1,767; 97.2%); IAA was substantial (kappa = 0.76). The dataset has 497 (27.3%) citations representing OSCC studies of potential prognostic biomarkers. The gold standard dataset is likely to be high quality and useful for future development and evaluation of filters for OSCC studies of potential prognostic biomarkers. The methodology we used is generalizable to other domains requiring a reference standard to evaluate the performance of search filters. A gold standard is essential because the labels regarding relevance enable computation of diagnostic metrics, such as sensitivity and specificity. Librarians and informationists with data analysis skills could contribute to developing gold standard datasets and subsequent filters tuned for their patrons' domains of interest.

  11. Partial verification bias and incorporation bias affected accuracy estimates of diagnostic studies for biomarkers that were part of an existing composite gold standard.

    PubMed

    Karch, Annika; Koch, Armin; Zapf, Antonia; Zerr, Inga; Karch, André

    2016-10-01

    To investigate how choice of gold standard biases estimates of sensitivity and specificity in studies reassessing the diagnostic accuracy of biomarkers that are already part of a lifetime composite gold standard (CGS). We performed a simulation study based on the real-life example of the biomarker "protein 14-3-3" used for diagnosing Creutzfeldt-Jakob disease. Three different types of gold standard were compared: perfect gold standard "autopsy" (available in a small fraction only; prone to partial verification bias), lifetime CGS (including the biomarker under investigation; prone to incorporation bias), and "best available" gold standard (autopsy if available, otherwise CGS). Sensitivity was unbiased when comparing 14-3-3 with autopsy but overestimated when using CGS or "best available" gold standard. Specificity of 14-3-3 was underestimated in scenarios comparing 14-3-3 with autopsy (up to 24%). In contrast, overestimation (up to 20%) was observed for specificity compared with CGS; this could be reduced to 0-10% when using the "best available" gold standard. Choice of gold standard affects considerably estimates of diagnostic accuracy. Using the "best available" gold standard (autopsy where available, otherwise CGS) leads to valid estimates of specificity, whereas sensitivity is estimated best when tested against autopsy alone. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Device and methods for "gold standard" registration of clinical 3D and 2D cerebral angiograms

    NASA Astrophysics Data System (ADS)

    Madan, Hennadii; Likar, Boštjan; Pernuš, Franjo; Å piclin, Žiga

    2015-03-01

    Translation of any novel and existing 3D-2D image registration methods into clinical image-guidance systems is limited due to lack of their objective validation on clinical image datasets. The main reason is that, besides the calibration of the 2D imaging system, a reference or "gold standard" registration is very difficult to obtain on clinical image datasets. In the context of cerebral endovascular image-guided interventions (EIGIs), we present a calibration device in the form of a headband with integrated fiducial markers and, secondly, propose an automated pipeline comprising 3D and 2D image processing, analysis and annotation steps, the result of which is a retrospective calibration of the 2D imaging system and an optimal, i.e., "gold standard" registration of 3D and 2D images. The device and methods were used to create the "gold standard" on 15 datasets of 3D and 2D cerebral angiograms, whereas each dataset was acquired on a patient undergoing EIGI for either aneurysm coiling or embolization of arteriovenous malformation. The use of the device integrated seamlessly in the clinical workflow of EIGI. While the automated pipeline eliminated all manual input or interactive image processing, analysis or annotation. In this way, the time to obtain the "gold standard" was reduced from 30 to less than one minute and the "gold standard" of 3D-2D registration on all 15 datasets of cerebral angiograms was obtained with a sub-0.1 mm accuracy.

  13. Suggested techniques, equipment, and standards for the testing of hand insecticide-spraying equipment

    PubMed Central

    Hall, Lawrence B.

    1955-01-01

    The new demands placed upon application equipment by the introduction of modern insecticides have revealed the deficiencies of this equipment when required for continuous use on a large scale. If adequate equipment is to be produced, specifications must be based not only on basic materials tests but also on “use” tests, in which the conditions of field use are simulated. The author outlines suggested techniques to be followed and standards to be adopted in testing the performance of compression sprayers and allied equipment, with reference to the following features: compression-sprayer tank fatigue; tank impact; pump resistance to bursting; pump resistance to collapse; pump friction; cut-off valve durability; constant-pressure valves; cut-off valve actuation; hose flexure; hose tension and bursting-pressure; hose friction; gaskets, valve faces, and similar non-metallic parts; nozzle-orifice erosion; and nozzle pattern. ImagesFIG. 1FIG. 14FIG. 20 PMID:14364189

  14. Primary Discussion on Standardized Management of Purchasing Large Equipments for Measurement Technology Institution

    NASA Astrophysics Data System (ADS)

    Hu, Chang; Hu, Juanli; Zhou, Qi; Yang, Yue

    In view of current situation and existing problem on purchasing equipment for measurement technology institution, this paper analyzes key factors that affect the standardization of equipment procurement and it proposes a set of scientific and standardized solutions for equipment procurement based on actual work.

  15. 42 CFR 493.1252 - Standard: Test systems, equipment, instruments, reagents, materials, and supplies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Standard: Test systems, equipment, instruments... REQUIREMENTS Quality System for Nonwaived Testing Analytic Systems § 493.1252 Standard: Test systems, equipment...) Temperature. (3) Humidity. (4) Protection of equipment and instruments from fluctuations and interruptions in...

  16. A multilingual gold-standard corpus for biomedical concept recognition: the Mantra GSC.

    PubMed

    Kors, Jan A; Clematide, Simon; Akhondi, Saber A; van Mulligen, Erik M; Rebholz-Schuhmann, Dietrich

    2015-09-01

    To create a multilingual gold-standard corpus for biomedical concept recognition. We selected text units from different parallel corpora (Medline abstract titles, drug labels, biomedical patent claims) in English, French, German, Spanish, and Dutch. Three annotators per language independently annotated the biomedical concepts, based on a subset of the Unified Medical Language System and covering a wide range of semantic groups. To reduce the annotation workload, automatically generated preannotations were provided. Individual annotations were automatically harmonized and then adjudicated, and cross-language consistency checks were carried out to arrive at the final annotations. The number of final annotations was 5530. Inter-annotator agreement scores indicate good agreement (median F-score 0.79), and are similar to those between individual annotators and the gold standard. The automatically generated harmonized annotation set for each language performed equally well as the best annotator for that language. The use of automatic preannotations, harmonized annotations, and parallel corpora helped to keep the manual annotation efforts manageable. The inter-annotator agreement scores provide a reference standard for gauging the performance of automatic annotation techniques. To our knowledge, this is the first gold-standard corpus for biomedical concept recognition in languages other than English. Other distinguishing features are the wide variety of semantic groups that are being covered, and the diversity of text genres that were annotated. © The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association.

  17. 40 CFR 60.253 - Standards for pneumatic coal-cleaning equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 7 2013-07-01 2013-07-01 false Standards for pneumatic coal-cleaning... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of Performance for Coal Preparation and Processing Plants § 60.253 Standards for pneumatic coal-cleaning equipment. (a) On and after...

  18. 40 CFR 60.253 - Standards for pneumatic coal-cleaning equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 6 2011-07-01 2011-07-01 false Standards for pneumatic coal-cleaning... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of Performance for Coal Preparation and Processing Plants § 60.253 Standards for pneumatic coal-cleaning equipment. (a) On and after...

  19. 40 CFR 60.253 - Standards for pneumatic coal-cleaning equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 7 2012-07-01 2012-07-01 false Standards for pneumatic coal-cleaning... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of Performance for Coal Preparation and Processing Plants § 60.253 Standards for pneumatic coal-cleaning equipment. (a) On and after...

  20. 40 CFR 60.253 - Standards for pneumatic coal-cleaning equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standards for pneumatic coal-cleaning... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of Performance for Coal Preparation and Processing Plants § 60.253 Standards for pneumatic coal-cleaning equipment. (a) On and after...

  1. 40 CFR 60.253 - Standards for pneumatic coal-cleaning equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 7 2014-07-01 2014-07-01 false Standards for pneumatic coal-cleaning... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of Performance for Coal Preparation and Processing Plants § 60.253 Standards for pneumatic coal-cleaning equipment. (a) On and after...

  2. 78 FR 55889 - Energy Conservation Program: Energy Conservation Standards for Commercial Refrigeration Equipment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-11

    ...The Energy Policy and Conservation Act of 1975 (EPCA), as amended, prescribes energy conservation standards for various consumer products and certain commercial and industrial equipment, including commercial refrigeration equipment (CRE). EPCA also requires the U.S. Department of Energy (DOE) to determine whether more-stringent, amended standards would be technologically feasible and economically justified, and would save a significant amount of energy. In this notice, DOE proposes amended energy conservation standards for commercial refrigeration equipment. The notice also announces a public meeting to receive comment on these proposed standards and associated analyses and results.

  3. Applying a statistical PTB detection procedure to complement the gold standard.

    PubMed

    Noor, Norliza Mohd; Yunus, Ashari; Bakar, S A R Abu; Hussin, Amran; Rijal, Omar Mohd

    2011-04-01

    This paper investigates a novel statistical discrimination procedure to detect PTB when the gold standard requirement is taken into consideration. Archived data were used to establish two groups of patients which are the control and test group. The control group was used to develop the statistical discrimination procedure using four vectors of wavelet coefficients as feature vectors for the detection of pulmonary tuberculosis (PTB), lung cancer (LC), and normal lung (NL). This discrimination procedure was investigated using the test group where the number of sputum positive and sputum negative cases that were correctly classified as PTB cases were noted. The proposed statistical discrimination method is able to detect PTB patients and LC with high true positive fraction. The method is also able to detect PTB patients that are sputum negative and therefore may be used as a complement to the gold standard. Copyright © 2010 Elsevier Ltd. All rights reserved.

  4. 78 FR 4873 - Electrical Protective Equipment Standard and the Electric Power Generation, Transmission, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-23

    ..., personal protective equipment, insulating and shielding materials, and insulated tools for working on or...] Electrical Protective Equipment Standard and the Electric Power Generation, Transmission, and Distribution... the information collection requirements specified in its standards on Electrical Protective Equipment...

  5. Comparison of EHR-based diagnosis documentation locations to a gold standard for risk stratification in patients with multiple chronic conditions.

    PubMed

    Martin, Shelby; Wagner, Jesse; Lupulescu-Mann, Nicoleta; Ramsey, Katrina; Cohen, Aaron; Graven, Peter; Weiskopf, Nicole G; Dorr, David A

    2017-08-02

    To measure variation among four different Electronic Health Record (EHR) system documentation locations versus 'gold standard' manual chart review for risk stratification in patients with multiple chronic illnesses. Adults seen in primary care with EHR evidence of at least one of 13 conditions were included. EHRs were manually reviewed to determine presence of active diagnoses, and risk scores were calculated using three different methodologies and five EHR documentation locations. Claims data were used to assess cost and utilization for the following year. Descriptive and diagnostic statistics were calculated for each EHR location. Criterion validity testing compared the gold standard verified diagnoses versus other EHR locations and risk scores in predicting future cost and utilization. Nine hundred patients had 2,179 probable diagnoses. About 70% of the diagnoses from the EHR were verified by gold standard. For a subset of patients having baseline and prediction year data (n=750), modeling showed that the gold standard was the best predictor of outcomes on average for a subset of patients that had these data. However, combining all data sources together had nearly equivalent performance for prediction as the gold standard. EHR data locations were inaccurate 30% of the time, leading to improvement in overall modeling from a gold standard from chart review for individual diagnoses. However, the impact on identification of the highest risk patients was minor, and combining data from different EHR locations was equivalent to gold standard performance. The reviewer's ability to identify a diagnosis as correct was influenced by a variety of factors, including completeness, temporality, and perceived accuracy of chart data.

  6. Development of a Consensus Standard for School Equipment: NSF/NSSEA 380

    ERIC Educational Resources Information Center

    Breitner, Ashlee

    2011-01-01

    For many years, the school supplies and equipment industry has investigated methods to ensure product safety and compliance across all its product categories. In early 2010, NSF International and the National School Supply and Equipment Association (NSSEA) came together to develop quality standards for products and equipment designed for use in…

  7. A consensus-based gold standard for the evaluation of mass casualty triage systems.

    PubMed

    Lerner, E Brooke; McKee, Courtney H; Cady, Charles E; Cone, David C; Colella, M Riccardo; Cooper, Arthur; Coule, Phillip L; Lairet, Julio R; Liu, J Marc; Pirrallo, Ronald G; Sasser, Scott M; Schwartz, Richard; Shepherd, Greene; Swienton, Raymond E

    2015-01-01

    Accuracy and effectiveness analyses of mass casualty triage systems are limited because there are no gold standard definitions for each of the triage categories. Until there is agreement on which patients should be identified by each triage category, it will be impossible to calculate sensitivity and specificity or to compare accuracy between triage systems. To develop a consensus-based, functional gold standard definition for each mass casualty triage category. National experts were recruited through the lead investigators' contacts and their suggested contacts. Key informant interviews were conducted to develop a list of potential criteria for defining each triage category. Panelists were interviewed in order of their availability until redundancy of themes was achieved. Panelists were blinded to each other's responses during the interviews. A modified Delphi survey was developed with the potential criteria identified during the interview and delivered to all recruited experts. In the early rounds, panelists could add, remove, or modify criteria. In the final rounds edits were made to the criteria until at least 80% agreement was achieved. Thirteen national and local experts were recruited to participate in the project. Six interviews were conducted. Three rounds of voting were performed, with 12 panelists participating in the first round, 12 in the second round, and 13 in the third round. After the first two rounds, the criteria were modified according to respondent suggestions. In the final round, over 90% agreement was achieved for all but one criterion. A single e-mail vote was conducted on edits to the final criterion and consensus was achieved. A consensus-based, functional gold standard definition for each mass casualty triage category was developed. These gold standard definitions can be used to evaluate the accuracy of mass casualty triage systems after an actual incident, during training, or for research.

  8. 77 FR 16769 - Energy Conservation Program for Certain Industrial Equipment: Energy Conservation Standards and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-22

    ... Conservation Program for Certain Industrial Equipment: Energy Conservation Standards and Test Procedures for...-Conditioning Engineers (ASHRAE)/Illuminating Engineering Society of North America (IESNA) Standard 90.1-2010... Industrial Equipment, which includes the commercial heating, air-conditioning, and water-heating equipment...

  9. 76 FR 62961 - Lifesaving Equipment: Production Testing and Harmonization With International Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-11

    ... CFR Parts 108, 117, et al. Lifesaving Equipment: Production Testing and Harmonization With... Equipment: Production Testing and Harmonization With International Standards AGENCY: Coast Guard, DHS... equipment, including launching appliances (winches and davits), release mechanisms, survival craft...

  10. 75 FR 53457 - Lifesaving Equipment: Production Testing and Harmonization With International Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-31

    ... approval process for all lifesaving equipment required under the various vessel and facility regulations in... buoyant apparatuses. If the proposed rule is made final, all equipment approved after the effective date... Equipment: Production Testing and Harmonization With International Standards; Proposed Rule #0;#0;Federal...

  11. Heavy Duty Equipment Mechanic. Apprenticeship Training Standards = Mecanicien d'equipement lourd. Normes de formation en apprentissage.

    ERIC Educational Resources Information Center

    Ontario Ministry of Skills Development, Toronto.

    These training standards for heavy duty equipment mechanics are intended to be used by apprentice/trainees, instructors, and companies in Ontario, Canada, as a blueprint for training or as a prerequisite for accreditation/certification. The training standards identify skills required for this occupation and its related training program. They are…

  12. 75 FR 28227 - National Emission Standards for Hazardous Air Pollutants: Gold Mine Ore Processing and Production...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-20

    ... published a proposed rule for mercury emissions from the gold mine ore processing and production area source... proposed rule (75 FR 22470). Several parties requested that EPA extend the comment period. EPA has granted...-AP48 National Emission Standards for Hazardous Air Pollutants: Gold Mine Ore Processing and Production...

  13. Epidural technique for postoperative pain: gold standard no more?

    PubMed

    Rawal, Narinder

    2012-01-01

    Epidural analgesia is a well-established technique that has commonly been regarded as the gold standard in postoperative pain management. However, newer, evidence-based outcome data show that the benefits of epidural analgesia are not as significant as previously believed. There are some benefits in a decrease in the incidence of cardiovascular and pulmonary complications, but these benefits are probably limited to high-risk patients undergoing major abdominal or thoracic surgery who receive thoracic epidural analgesia with local anaesthetic drugs only. There is increasing evidence that less invasive regional analgesic techniques are as effective as epidural analgesia. These include paravertebral block for thoracotomy, femoral block for total hip and knee arthroplasty, wound catheter infusions for cesarean delivery, and local infiltration analgesia techniques for lower limb joint arthroplasty. Wound infiltration techniques and their modifications are simple and safe alternatives for a variety of other surgical procedures. Although pain relief associated with epidural analgesia can be outstanding, clinicians expect more from this invasive, high-cost, labour-intensive technique. The number of indications for the use of epidural analgesia seems to be decreasing for a variety of reasons. The decision about whether to continue using epidural techniques should be guided by regular institutional audits and careful risk-benefit assessment rather than by tradition. For routine postoperative analgesia, epidural analgesia may no longer be considered the gold standard.

  14. 77 FR 72411 - The Standard on Personal Protective Equipment (PPE) for Shipyard Employment; Extension of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-05

    ... Standard on Personal Protective Equipment (PPE) for Shipyard Employment; Extension of the Office of... requirements specified in the Standard on Personal Protective Equipment (PPE) for Shipyard Employment (29 CFR... information collection requirements contained in the Standard on Personal Protective Equipment (PPE) for...

  15. 40 CFR 82.158 - Standards for recycling and recovery equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Standards for recycling and recovery... PROGRAMS (CONTINUED) PROTECTION OF STRATOSPHERIC OZONE Recycling and Emissions Reduction § 82.158 Standards for recycling and recovery equipment. (a) Effective September 22, 2003, all manufacturers and...

  16. 40 CFR 82.158 - Standards for recycling and recovery equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Standards for recycling and recovery... PROGRAMS (CONTINUED) PROTECTION OF STRATOSPHERIC OZONE Recycling and Emissions Reduction § 82.158 Standards for recycling and recovery equipment. (a) Effective September 22, 2003, all manufacturers and...

  17. 40 CFR 82.158 - Standards for recycling and recovery equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Standards for recycling and recovery... PROGRAMS (CONTINUED) PROTECTION OF STRATOSPHERIC OZONE Recycling and Emissions Reduction § 82.158 Standards for recycling and recovery equipment. (a) Effective September 22, 2003, all manufacturers and...

  18. 40 CFR 82.158 - Standards for recycling and recovery equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Standards for recycling and recovery... PROGRAMS (CONTINUED) PROTECTION OF STRATOSPHERIC OZONE Recycling and Emissions Reduction § 82.158 Standards for recycling and recovery equipment. (a) Effective September 22, 2003, all manufacturers and...

  19. 40 CFR 82.158 - Standards for recycling and recovery equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Standards for recycling and recovery... PROGRAMS (CONTINUED) PROTECTION OF STRATOSPHERIC OZONE Recycling and Emissions Reduction § 82.158 Standards for recycling and recovery equipment. (a) Effective September 22, 2003, all manufacturers and...

  20. Validating Automated Essay Scoring: A (Modest) Refinement of the "Gold Standard"

    ERIC Educational Resources Information Center

    Powers, Donald E.; Escoffery, David S.; Duchnowski, Matthew P.

    2015-01-01

    By far, the most frequently used method of validating (the interpretation and use of) automated essay scores has been to compare them with scores awarded by human raters. Although this practice is questionable, human-machine agreement is still often regarded as the "gold standard." Our objective was to refine this model and apply it to…

  1. Diagnosis of Helicobacter pylori: What should be the gold standard?

    PubMed Central

    Patel, Saurabh Kumar; Pratap, Chandra Bhan; Jain, Ashok Kumar; Gulati, Anil Kumar; Nath, Gopal

    2014-01-01

    plaques and environmental specimens. There are speculations for false positivity due to detection of non-pylori Helicobacters due to genetic sharing; and false negativity due to low bacterial counts and presence of PCR inhibitors. However, specimen collection, transportation and processing do not require speed and special conditions. PCR based diagnosis may be considered as gold standard by designing primers extremely specific to H. pylori and targeting at least more than one conserved genes. Similarly specificity of PCR may be improved by use of internal Primers. Further, nested PCR will take care of false negatives by countering the effect of PCR inhibitors and low bacterial counts. Therefore, nested PCR based methods if performed properly, may be proposed as gold standard test. PMID:25278682

  2. 33 CFR 155.380 - Oily water separating equipment and bilge alarm approval standards.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... PREVENTION REGULATIONS FOR VESSELS Vessel Equipment § 155.380 Oily water separating equipment and bilge alarm approval standards. (a) On U.S. inspected ships, oily water separating equipment and bilge alarms must be... routine maintenance of the oily water separating equipment and the bilge alarm must be clearly defined by...

  3. 33 CFR 155.380 - Oily water separating equipment and bilge alarm approval standards.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PREVENTION REGULATIONS FOR VESSELS Vessel Equipment § 155.380 Oily water separating equipment and bilge alarm approval standards. (a) On U.S. inspected ships, oily water separating equipment and bilge alarms must be... routine maintenance of the oily water separating equipment and the bilge alarm must be clearly defined by...

  4. 33 CFR 155.380 - Oily water separating equipment and bilge alarm approval standards.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... PREVENTION REGULATIONS FOR VESSELS Vessel Equipment § 155.380 Oily water separating equipment and bilge alarm approval standards. (a) On U.S. inspected ships, oily water separating equipment and bilge alarms must be... routine maintenance of the oily water separating equipment and the bilge alarm must be clearly defined by...

  5. 33 CFR 155.380 - Oily water separating equipment and bilge alarm approval standards.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PREVENTION REGULATIONS FOR VESSELS Vessel Equipment § 155.380 Oily water separating equipment and bilge alarm approval standards. (a) On U.S. inspected ships, oily water separating equipment and bilge alarms must be... routine maintenance of the oily water separating equipment and the bilge alarm must be clearly defined by...

  6. Seeking a Valid Gold Standard for an Innovative, Dialect-Neutral Language Test

    ERIC Educational Resources Information Center

    Pearson, Barbara Zurer; Jackson, Janice E.; Wu, Haotian

    2014-01-01

    Purpose: In this study, the authors explored alternative gold standards to validate an innovative, dialect-neutral language assessment. Method: Participants were 78 African American children, ages 5;0 (years;months) to 6;11. Twenty participants had previously been identified as having language impairment. The Diagnostic Evaluation of Language…

  7. Population Health Metrics Research Consortium gold standard verbal autopsy validation study: design, implementation, and development of analysis datasets

    PubMed Central

    2011-01-01

    Background Verbal autopsy methods are critically important for evaluating the leading causes of death in populations without adequate vital registration systems. With a myriad of analytical and data collection approaches, it is essential to create a high quality validation dataset from different populations to evaluate comparative method performance and make recommendations for future verbal autopsy implementation. This study was undertaken to compile a set of strictly defined gold standard deaths for which verbal autopsies were collected to validate the accuracy of different methods of verbal autopsy cause of death assignment. Methods Data collection was implemented in six sites in four countries: Andhra Pradesh, India; Bohol, Philippines; Dar es Salaam, Tanzania; Mexico City, Mexico; Pemba Island, Tanzania; and Uttar Pradesh, India. The Population Health Metrics Research Consortium (PHMRC) developed stringent diagnostic criteria including laboratory, pathology, and medical imaging findings to identify gold standard deaths in health facilities as well as an enhanced verbal autopsy instrument based on World Health Organization (WHO) standards. A cause list was constructed based on the WHO Global Burden of Disease estimates of the leading causes of death, potential to identify unique signs and symptoms, and the likely existence of sufficient medical technology to ascertain gold standard cases. Blinded verbal autopsies were collected on all gold standard deaths. Results Over 12,000 verbal autopsies on deaths with gold standard diagnoses were collected (7,836 adults, 2,075 children, 1,629 neonates, and 1,002 stillbirths). Difficulties in finding sufficient cases to meet gold standard criteria as well as problems with misclassification for certain causes meant that the target list of causes for analysis was reduced to 34 for adults, 21 for children, and 10 for neonates, excluding stillbirths. To ensure strict independence for the validation of methods and assessment of

  8. 48 CFR 908.7112 - Materials handling equipment replacement standards.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Materials handling equipment replacement standards. 908.7112 Section 908.7112 Federal Acquisition Regulations System DEPARTMENT OF ENERGY COMPETITION ACQUISITION PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES Acquisition of...

  9. Reassessing RCTs as the "Gold Standard": Synergy Not Separatism in Evaluation Designs

    ERIC Educational Resources Information Center

    Hanley, Pam; Chambers, Bette; Haslam, Jonathan

    2016-01-01

    Randomised controlled trials (RCTs) are increasingly used to evaluate educational interventions in the UK. However, RCTs remain controversial for some elements of the research community. This paper argues that the widespread use of the term "gold standard" to describe RCTs is problematic, as it implies that other research methods are…

  10. After the Gold Rush: Questioning the "Gold Standard" and Reappraising the Status of Experiment and Randomized Controlled Trials in Education

    ERIC Educational Resources Information Center

    Thomas, Gary

    2016-01-01

    The past few years have seen a resurgence of faith in experimentation in education inquiry, and particularly in randomized controlled trials (RCTs). Proponents of such research have succeeded in bringing into common parlance the term "gold standard," which suggests that research emerging from any other design frame fails to achieve the…

  11. 76 FR 62714 - Lifesaving Equipment: Production Testing and Harmonization With International Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-11

    ... apply to: prototypes (new designs) submitted after January 1, 2012; production testing of designs... Lifesaving Equipment: Production Testing and Harmonization With International Standards AGENCY: Coast Guard... and Standards Directorate, Office of Design and Engineering Standards, Lifesaving and Fire Safety...

  12. A studentized permutation test for three-arm trials in the 'gold standard' design.

    PubMed

    Mütze, Tobias; Konietschke, Frank; Munk, Axel; Friede, Tim

    2017-03-15

    The 'gold standard' design for three-arm trials refers to trials with an active control and a placebo control in addition to the experimental treatment group. This trial design is recommended when being ethically justifiable and it allows the simultaneous comparison of experimental treatment, active control, and placebo. Parametric testing methods have been studied plentifully over the past years. However, these methods often tend to be liberal or conservative when distributional assumptions are not met particularly with small sample sizes. In this article, we introduce a studentized permutation test for testing non-inferiority and superiority of the experimental treatment compared with the active control in three-arm trials in the 'gold standard' design. The performance of the studentized permutation test for finite sample sizes is assessed in a Monte Carlo simulation study under various parameter constellations. Emphasis is put on whether the studentized permutation test meets the target significance level. For comparison purposes, commonly used Wald-type tests, which do not make any distributional assumptions, are included in the simulation study. The simulation study shows that the presented studentized permutation test for assessing non-inferiority in three-arm trials in the 'gold standard' design outperforms its competitors, for instance the test based on a quasi-Poisson model, for count data. The methods discussed in this paper are implemented in the R package ThreeArmedTrials which is available on the comprehensive R archive network (CRAN). Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  13. Glucose Measurement: Time for a Gold Standard

    PubMed Central

    Hagvik, Joakim

    2007-01-01

    There is no internationally recognized reference method for the measurement of blood glucose. The Centers for Disease Control and Prevention (CDC) highlighted the need for standardization some years ago when a project was started. The project objectives were to (1) investigate whether there are significant differences in calibration levels among currently used glucose monitors for home use and (2) develop a reference method for glucose determination. A first study confirmed the assumption that currently used home-use monitors differ significantly and that standardization is necessary in order to minimize variability and to improve patient care. As a reference method, CDC recommended a method based on isotope dilution gas chromatography–mass spectrometry, an assay that has received support from clinical chemists worldwide. CDC initiated a preliminary study to establish the suitability of this method, but then the project came to a halt. It is hoped that CDC, with support from the industry, as well as academic and professional organizations such as the American Association for Clinical Chemistry and International Federation of Clinical Chemistry and Laboratory Medicine, will be able to finalize the project and develop the long-awaited and much needed “gold standard” for glucose measurement. PMID:19888402

  14. 36 CFR 1254.106 - What are NARA's equipment standards?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false What are NARA's equipment standards? 1254.106 Section 1254.106 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION PUBLIC AVAILABILITY AND USE USING RECORDS AND DONATED HISTORICAL MATERIALS Microfilming Archival...

  15. 36 CFR 1254.106 - What are NARA's equipment standards?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false What are NARA's equipment standards? 1254.106 Section 1254.106 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION PUBLIC AVAILABILITY AND USE USING RECORDS AND DONATED HISTORICAL MATERIALS Microfilming Archival...

  16. Evaluation of diagnostic accuracy in detecting ordered symptom statuses without a gold standard

    PubMed Central

    Wang, Zheyu; Zhou, Xiao-Hua; Wang, Miqu

    2011-01-01

    Our research is motivated by 2 methodological problems in assessing diagnostic accuracy of traditional Chinese medicine (TCM) doctors in detecting a particular symptom whose true status has an ordinal scale and is unknown—imperfect gold standard bias and ordinal scale symptom status. In this paper, we proposed a nonparametric maximum likelihood method for estimating and comparing the accuracy of different doctors in detecting a particular symptom without a gold standard when the true symptom status had an ordered multiple class. In addition, we extended the concept of the area under the receiver operating characteristic curve to a hyper-dimensional overall accuracy for diagnostic accuracy and alternative graphs for displaying a visual result. The simulation studies showed that the proposed method had good performance in terms of bias and mean squared error. Finally, we applied our method to our motivating example on assessing the diagnostic abilities of 5 TCM doctors in detecting symptoms related to Chills disease. PMID:21209155

  17. 40 CFR 63.1159 - Operational and equipment standards for existing, new, or reconstructed sources.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... atmosphere shall be equipped with a local fume capture system, ventilated through an air pollution control... pollution control equipment and monitoring equipment in a manner consistent with safety and good air... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS...

  18. 40 CFR 63.1159 - Operational and equipment standards for existing, new, or reconstructed sources.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... atmosphere shall be equipped with a local fume capture system, ventilated through an air pollution control... pollution control equipment and monitoring equipment in a manner consistent with safety and good air... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS...

  19. Standardized methods for photography in procedural dermatology using simple equipment.

    PubMed

    Hexsel, Doris; Hexsel, Camile L; Dal'Forno, Taciana; Schilling de Souza, Juliana; Silva, Aline F; Siega, Carolina

    2017-04-01

    Photography is an important tool in dermatology. Reproducing the settings of before photos after interventions allows more accurate evaluation of treatment outcomes. In this article, we describe standardized methods and tips to obtain photographs, both for clinical practice and research procedural dermatology, using common equipment. Standards for the studio, cameras, photographer, patients, and framing are presented in this article. © 2017 The International Society of Dermatology.

  20. 38 CFR 17.155 - Minimum standards of safety and quality for automotive adaptive equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... safety and quality for automotive adaptive equipment. 17.155 Section 17.155 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Automotive Equipment and Driver Training § 17.155 Minimum standards of safety and quality for automotive adaptive equipment. (a) The Under Secretary for...

  1. 38 CFR 17.155 - Minimum standards of safety and quality for automotive adaptive equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... safety and quality for automotive adaptive equipment. 17.155 Section 17.155 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Automotive Equipment and Driver Training § 17.155 Minimum standards of safety and quality for automotive adaptive equipment. (a) The Under Secretary for...

  2. 38 CFR 17.155 - Minimum standards of safety and quality for automotive adaptive equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... safety and quality for automotive adaptive equipment. 17.155 Section 17.155 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Automotive Equipment and Driver Training § 17.155 Minimum standards of safety and quality for automotive adaptive equipment. (a) The Under Secretary for...

  3. 38 CFR 17.155 - Minimum standards of safety and quality for automotive adaptive equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... safety and quality for automotive adaptive equipment. 17.155 Section 17.155 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Automotive Equipment and Driver Training § 17.155 Minimum standards of safety and quality for automotive adaptive equipment. (a) The Under Secretary for...

  4. SODA FOUNTAIN-LUNCHEONETTE EQUIPMENT AND APPURTENANCES. NATIONAL SANITATION FOUNDATION STANDARD NO. 1.

    ERIC Educational Resources Information Center

    National Sanitation Foundation, Ann Arbor, MI.

    THIS STANDARD OF SODA FOUNTAIN-LUNCHEONETTE EQUIPMENT IS THE FIRST IN A SERIES OF NATIONAL SANITATION FOUNDATION STANDARDS. THESE STANDARDS ARE ISSUED IN RECOGNITION OF THE LONG FELT NEED FOR A COMMON UNDERSTANDING OF THE PROBLEMS OF SANITATION INVOLVING INDUSTRIAL AND ADMINISTRATIVE HEALTH OFFICIALS WHOSE OBLIGATION IT IS TO ENFORCE REGULATIONS.…

  5. 38 CFR 17.155 - Minimum standards of safety and quality for automotive adaptive equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... justify development of formal standards, such equipment will be inspected and, if in order, approved for... safety and quality for automotive adaptive equipment. 17.155 Section 17.155 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Automotive Equipment and Driver Training § 17.155...

  6. Electrochemical Assay of Gold-Plating Solutions

    NASA Technical Reports Server (NTRS)

    Chiodo, R.

    1982-01-01

    Gold content of plating solution is assayed by simple method that required only ordinary electrochemical laboratory equipment and materials. Technique involves electrodeposition of gold from solution onto electrode, the weight gain of which is measured. Suitable fast assay methods are economically and practically necessary in electronics and decorative-plating industries. If gold content in plating bath is too low, poor plating may result, with consequent economic loss to user.

  7. Fungus-mediated synthesis of gold nanoparticles and standardization of parameters for its biosynthesis.

    PubMed

    Tidke, Pritish R; Gupta, Indarchand; Gade, Aniket K; Rai, Mahendra

    2014-12-01

    We report the extracellular biosynthesis of gold nanoparticles (AuNPs) using a fungus Fusarium acuminatum. Mycosynthesis of Au-NPs was carried out by challenging the fungal cells filtrate with HAuCl 4 solution (1 mM), as nanoparticles synthesizing enzyme secrete extracellularly by the fungi. The AuNPs were characterized with the help of UV-Visible spectrophotometer, Fourier Transform Infrared spectroscopy, Zeta Potential, X-ray diffraction (XRD) and Transmission electron microscopy (TEM). We observed absorbance peak in between 520 nm-550 nm corresponding to the surface plasmon absorbance of the gold nanoparticles. The nanoparticles synthesized in the present investigation were found to be capped by proteins. XRD results showed that the distinctive formation of crystalline gold nanoparticles in the solution. The spherical and polydispersed AuNPs in the range 8 to 28 nm with average size of 17 nm were observed by TEM analysis. We also standardized the parameters like the effect of pH, temperature and salt concentration on the biosynthesis of gold nanoparticles. It was found that acidic pH, 1 mM salt concentration and 37 (°)C temperature were found to be optimum for the synthesis of Au-NPs. Therefore, the present study introduces the easy, better and cheaper method for biosynthesis of AuNPs.

  8. 77 FR 28927 - Energy Conservation Program for Certain Industrial Equipment: Energy Conservation Standards and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-16

    ...The U.S. Department of Energy (DOE) is amending its energy conservation standards for small, large, and very large water-cooled and evaporatively-cooled commercial package air conditioners, and variable refrigerant flow (VRF) water-source heat pumps less than 17,000 Btu/h. DOE is adopting new energy conservation standards for computer room air conditioners and VRF water-source heat pumps with a cooling capacity at or greater than 135,000 Btu/h and less than 760,000 Btu/h. Pursuant to the Energy Policy and Conservation Act of 1975 (EPCA), as amended, DOE must assess whether the uniform national standards for these covered equipment need to be updated each time the corresponding industry standard--the American National Standards Institute (ANSI)/American Society of Heating, Refrigerating, and Air- Conditioning Engineers (ASHRAE)/Illuminating Engineering Society of North America (IESNA) Standard 90.1 (ASHRAE Standard 90.1)--is amended, which most recently occurred on October 29, 2010. The levels DOE is adopting are the same as the efficiency levels specified in ASHRAE Standard 90.1-2010. DOE has determined that the ASHRAE Standard 90.1- 2010 efficiency levels for the equipment types listed above are more stringent than existing Federal energy conservation standards and will result in economic and energy savings compared existing energy conservation standards. Furthermore, DOE has concluded that clear and convincing evidence does not exist, as would justify more-stringent standard levels than the efficiency levels in ASHRAE Standard 90.1-2010 for any of the equipment classes. DOE is also updating the current Federal test procedures or, for certain equipment, adopting new test procedures to incorporate by reference the most current versions of the relevant industry test procedures specified in ASHRAE Standard 90.1- 2010. Furthermore, DOE is adopting additional test procedure provisions to include with modification certain instructions from Air- Conditioning, Heating

  9. Assessing operating characteristics of CAD algorithms in the absence of a gold standard

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roy Choudhury, Kingshuk; Paik, David S.; Yi, Chin A.

    2010-04-15

    Purpose: The authors examine potential bias when using a reference reader panel as ''gold standard'' for estimating operating characteristics of CAD algorithms for detecting lesions. As an alternative, the authors propose latent class analysis (LCA), which does not require an external gold standard to evaluate diagnostic accuracy. Methods: A binomial model for multiple reader detections using different diagnostic protocols was constructed, assuming conditional independence of readings given true lesion status. Operating characteristics of all protocols were estimated by maximum likelihood LCA. Reader panel and LCA based estimates were compared using data simulated from the binomial model for a range ofmore » operating characteristics. LCA was applied to 36 thin section thoracic computed tomography data sets from the Lung Image Database Consortium (LIDC): Free search markings of four radiologists were compared to markings from four different CAD assisted radiologists. For real data, bootstrap-based resampling methods, which accommodate dependence in reader detections, are proposed to test of hypotheses of differences between detection protocols. Results: In simulation studies, reader panel based sensitivity estimates had an average relative bias (ARB) of -23% to -27%, significantly higher (p-value <0.0001) than LCA (ARB -2% to -6%). Specificity was well estimated by both reader panel (ARB -0.6% to -0.5%) and LCA (ARB 1.4%-0.5%). Among 1145 lesion candidates LIDC considered, LCA estimated sensitivity of reference readers (55%) was significantly lower (p-value 0.006) than CAD assisted readers' (68%). Average false positives per patient for reference readers (0.95) was not significantly lower (p-value 0.28) than CAD assisted readers' (1.27). Conclusions: Whereas a gold standard based on a consensus of readers may substantially bias sensitivity estimates, LCA may be a significantly more accurate and consistent means for evaluating diagnostic accuracy.« less

  10. Development of standardized component\\0x2010based equipment specifications and transition plan into a predictive maintenance strategy.

    DOT National Transportation Integrated Search

    2015-12-01

    This project investigated INDOT equipment records and equipment industry standards to produce standard equipment specifications : and a predictive maintenance schedule for the more than 1100 single and tandem axle trucks in use at INDOT. The research...

  11. Gold standards and expert panels: a pulmonary nodule case study with challenges and solutions

    NASA Astrophysics Data System (ADS)

    Miller, Dave P.; O'Shaughnessy, Kathryn F.; Wood, Susan A.; Castellino, Ronald A.

    2004-05-01

    Comparative evaluations of reader performance using different modalities, e.g. CT with computer-aided detection (CAD) vs. CT without CAD, generally require a "truth" definition based on a gold standard. There are many situations in which a true invariant gold standard is impractical or impossible to obtain. For instance, small pulmonary nodules are generally not assessed by biopsy or resection. In such cases, it is common to use a unanimous consensus or majority agreement from an expert panel as a reference standard for actionability in lieu of the unknown gold standard for disease. Nonetheless, there are three major concerns about expert panel reference standards: (1) actionability is not synonymous with disease (2) it may be possible to obtain different conclusions about which modality is better using different rules (e.g. majority vs. unanimous consensus), and (3) the variability associated with the panelists is not formally captured in the p-values or confidence intervals that are generally produced for estimating the extent to which one modality is superior to the other. A multi-reader-multi-case (MRMC) receiver operating characteristic (ROC) study was performed using 90 cases, 15 readers, and a reference truth based on 3 experienced panelists. The primary analyses were conducted using a reference truth of unanimous consensus regarding actionability (3 out of 3 panelists). To assess the three concerns noted above: (1) additional data from the original radiology reports were compared to the panel (2) the complete analysis was repeated using different definitions of truth, and (3) bootstrap analyses were conducted in which new truth panels were constructed by picking 1, 2, or 3 panelists at random. The definition of the reference truth affected the results for each modality (CT with CAD and CT without CAD) considered by itself, but the effects were similar, so the primary analysis comparing the modalities was robust to the choice of the reference truth.

  12. Reduction of ETS-VI Laser Communication Equipment Optical-Downlink Telemetry Collected During GOLD

    NASA Technical Reports Server (NTRS)

    Toyoshima, M.; Araki, K.; Arimoto, Y.; Toyoda, M.; Jeganathan, M.; Wilson, K.; Lesh, J. R.

    1997-01-01

    Free-space laser communications experiments were conducted between the laser communication equipment (LCE) on board the Japanese Engineering Test Satellite VI (ETS-VI) and the ground station located at the Table Mountain Facility (TMF) during late 1995 and early 1996. This article describes the on-line data reduction process used to decode LCE telemetry (called E2) downlinked on the optical carrier during the Ground/Orbiter Lasercomm Demonstration (GOLD) experiments. The LCE has the capability of transmitting real-time sensor and status information at 128 kbps by modulating the onboard diode laser. The optical downlink was detected on the ground, bit synchronized, and the resulting data stream stored on a data recorder. The recorded data were subsequently decoded by on-line data processing that included cross-correlation of the known telemetry data format and the downlink data stream. Signals obtained from the processing can be useful not only in evaluating the characteristics of the LCE but also in understanding uplink and downlink signal quality.

  13. 75 FR 21567 - Federal Motor Vehicle Safety Standard No. 108; Lamp, Reflective Devices and Associated Equipment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... Federal Motor Vehicle Safety Standard No. 108; Lamp, Reflective Devices and Associated Equipment; Denial... Motor Vehicle Safety Standard (FMVSS) No. 108; Lamps, reflective devices, and associated equipment... physical filaments in the lamp. Specifically, BMW requested that paragraph S10.17.1.1.2 \\4\\ of the...

  14. From plastic to gold: a unified classification scheme for reference standards in medical image processing

    NASA Astrophysics Data System (ADS)

    Lehmann, Thomas M.

    2002-05-01

    Reliable evaluation of medical image processing is of major importance for routine applications. Nonetheless, evaluation is often omitted or methodically defective when novel approaches or algorithms are introduced. Adopted from medical diagnosis, we define the following criteria to classify reference standards: 1. Reliance, if the generation or capturing of test images for evaluation follows an exactly determined and reproducible protocol. 2. Equivalence, if the image material or relationships considered within an algorithmic reference standard equal real-life data with respect to structure, noise, or other parameters of importance. 3. Independence, if any reference standard relies on a different procedure than that to be evaluated, or on other images or image modalities than that used routinely. This criterion bans the simultaneous use of one image for both, training and test phase. 4. Relevance, if the algorithm to be evaluated is self-reproducible. If random parameters or optimization strategies are applied, reliability of the algorithm must be shown before the reference standard is applied for evaluation. 5. Significance, if the number of reference standard images that are used for evaluation is sufficient large to enable statistically founded analysis. We demand that a true gold standard must satisfy the Criteria 1 to 3. Any standard only satisfying two criteria, i.e., Criterion 1 and Criterion 2 or Criterion 1 and Criterion 3, is referred to as silver standard. Other standards are termed to be from plastic. Before exhaustive evaluation based on gold or silver standards is performed, its relevance must be shown (Criterion 4) and sufficient tests must be carried out to found statistical analysis (Criterion 5). In this paper, examples are given for each class of reference standards.

  15. Getting the Gold Treatment

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Epner Technology, Inc., worked with Goddard Space Center to apply gold coating to the Vegetation Canopy Lidar (VCL) mirror. This partnership resulted in new commercial applications for Epner's LaserGold(R) process in the automotive industry. Previously, the company did not have equipment large enough to handle the plating of the stainless steel panels cost effectively. Seeing a chance to renew this effort, Epner Technology and Goddard entered into an agreement by which NASA would fund the facility needed to do the gold-plating, and Epner Technology would cover all other costs as part of their internal research and development. The VCL mirror project proceeded successfully, fulfilling Goddard's needs and leaving Epner Technology with a new facility to provide LaserGold for the automotive industry. The new capability means increased power savings and improvements in both quality and production time for BMW Manufacturing Corporation of Spartanburg, South Carolina, and Cadillac of Detroit, Michigan, as well as other manufacturers who have implemented Epner Technology's LaserGold process. LaserGold(R) is a registered trademark of Epner Technology, Inc.

  16. A Preliminary Anthropometry Standard for Australian Army Equipment Evaluation

    DTIC Science & Technology

    2014-08-01

    UNCLASSIFIED Authors Mark Edwards Land Division Mark Edwards holds an undergraduate degree in Industrial Design , a Masters in Ergonomics ...equipment. Given that a built system is not a requirement of the processes described, this standard can also be used early in the design process to de...risk the design process. It must be noted that the data provided in this report are representative of the 2012 ADF Army population. The impacts

  17. 42 CFR 493.1252 - Standard: Test systems, equipment, instruments, reagents, materials, and supplies.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 5 2014-10-01 2014-10-01 false Standard: Test systems, equipment, instruments, reagents, materials, and supplies. 493.1252 Section 493.1252 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Quality System for Nonwaived...

  18. 40 CFR 63.305 - Alternative standards for coke oven doors equipped with sheds.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... SOURCE CATEGORIES National Emission Standards for Coke Oven Batteries § 63.305 Alternative standards for coke oven doors equipped with sheds. (a) The owner or operator of a new or existing coke oven battery... the efficiency of the control device for removal of particulate matter by conducting measurements at...

  19. 40 CFR 63.305 - Alternative standards for coke oven doors equipped with sheds.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SOURCE CATEGORIES National Emission Standards for Coke Oven Batteries § 63.305 Alternative standards for coke oven doors equipped with sheds. (a) The owner or operator of a new or existing coke oven battery... the efficiency of the control device for removal of particulate matter by conducting measurements at...

  20. 40 CFR 63.305 - Alternative standards for coke oven doors equipped with sheds.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... SOURCE CATEGORIES National Emission Standards for Coke Oven Batteries § 63.305 Alternative standards for coke oven doors equipped with sheds. (a) The owner or operator of a new or existing coke oven battery... the efficiency of the control device for removal of particulate matter by conducting measurements at...

  1. 40 CFR 63.305 - Alternative standards for coke oven doors equipped with sheds.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... SOURCE CATEGORIES National Emission Standards for Coke Oven Batteries § 63.305 Alternative standards for coke oven doors equipped with sheds. (a) The owner or operator of a new or existing coke oven battery... the efficiency of the control device for removal of particulate matter by conducting measurements at...

  2. 40 CFR 63.305 - Alternative standards for coke oven doors equipped with sheds.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... SOURCE CATEGORIES National Emission Standards for Coke Oven Batteries § 63.305 Alternative standards for coke oven doors equipped with sheds. (a) The owner or operator of a new or existing coke oven battery... the efficiency of the control device for removal of particulate matter by conducting measurements at...

  3. SpaceFibre: The Standard, Simulation, IP Cores and Test Equipment

    NASA Astrophysics Data System (ADS)

    Parkes, Steve; McClements, Chris; McLaren, David; Ferrer Florit, Albert; Gonzalez Villafranca, Alberto

    2015-09-01

    SpaceFibre is an emerging new standard for spacecraft on-board data-handling networks. Initially targeted to deliver multi-Gbit/s data rates for synthetic aperture radar and high-resolution, multi-spectral imaging instruments, SpaceFibre has developed into a unified network technology that integrates high bandwidth, with low latency, quality of service (QoS) and fault detection, isolation and recovery (FDIR). Furthermore SpaceFibre is backwards compatible with the widely used SpaceWire standard at the network level allowing simple interconnection of existing SpaceWire equipment to a SpaceFibre link or network. Developed by the University of Dundee for the European Space Agency (ESA) SpaceFibre is able to operate over fibre-optic and electrical cable and supports data rates of 2 Gbit/s in the near future and up to 5 Gbit/s long-term. Multi-laning improves the data-rate further to well over 20 Gbits/s. This paper details the current state of SpaceFibre which is now in the process of formal standardisation by the European Cooperation for Space Standardization (ECSS). It describes the SpaceFibre IP core being developed for ESA. The design of a SpaceFibre demonstration board is introduced and available SpaceFibre test and development equipment is described. The way in which several SpaceWire links can be concentrated over a single SpaceFibre link will be explained.

  4. Development of standardized component\\0x2010based equipment specifications and transition plan into a predictive maintenance strategy : final report.

    DOT National Transportation Integrated Search

    2015-12-01

    This project investigated INDOT equipment records and equipment industry standards to produce standard equipment specifications : and a predictive maintenance schedule for the more than 1100 single and tandem axle trucks in use at INDOT. The research...

  5. Diagnostic accuracy of tuberculous lymphadenitis fine needle aspiration biopsy confirmed by PCR as gold standard

    NASA Astrophysics Data System (ADS)

    DSuryadi; Delyuzar; Soekimin

    2018-03-01

    Indonesia is the second country with the TB (tuberculosis) burden in the world. Improvement in controlling TB and reducing the complications can accelerate early diagnosis and correct treatment. PCR test is a gold standard. However, it is quite expensive for routine diagnosis. Therefore, an accurate and cheaper diagnostic method such as fine needle aspiration biopsy is needed. The study aimsto determine the accuracy of fine needle aspiration biopsy cytology in the diagnosis of tuberculous lymphadenitis. A cross-sectional analytic study was conducted to the samples from patients suspected with tuberculous lymphadenitis. The fine needle aspiration biopsy (FNAB)test was performed and confirmed by PCR test.There is a comparison to the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of both methods. Sensitivity (92.50%), specificity (96.49%), accuracy (94.85%), positive predictive value (94.87%) and negative predictive value (94.83%) were in FNAB test compared to gold standard. We concluded that fine needle aspiration biopsy is a recommendation for a cheaper and accurate diagnostic test for tuberculous lymphadenitis diagnosis.

  6. Twenty years after Erich Muhe: Persisting controversies with the gold standard of laparoscopic cholecystectomy.

    PubMed

    Jani, Kalpesh; Rajan, P S; Sendhilkumar, K; Palanivelu, C

    2006-06-01

    This review article is a tribute to the genius of Professor Erich Muhe, a man ahead of his times. We trace the development of laparoscopic cholecystectomy and detail the tribulations faced by Muhe. On the occasion of the twentieth anniversary of the first laparoscopic cholecystectomy, we take another look at some of the controversies surrounding this gold standard in the management of gallbladder disease.

  7. Twenty years after Erich Muhe: Persisting controversies with the gold standard of laparoscopic cholecystectomy

    PubMed Central

    Jani, Kalpesh; Rajan, P S; Sendhilkumar, K; Palanivelu, C

    2006-01-01

    This review article is a tribute to the genius of Professor Erich Muhe, a man ahead of his times. We trace the development of laparoscopic cholecystectomy and detail the tribulations faced by Muhe. On the occasion of the twentieth anniversary of the first laparoscopic cholecystectomy, we take another look at some of the controversies surrounding this gold standard in the management of gallbladder disease PMID:21170235

  8. Practical no-gold-standard evaluation framework for quantitative imaging methods: application to lesion segmentation in positron emission tomography

    PubMed Central

    Jha, Abhinav K.; Mena, Esther; Caffo, Brian; Ashrafinia, Saeed; Rahmim, Arman; Frey, Eric; Subramaniam, Rathan M.

    2017-01-01

    Abstract. Recently, a class of no-gold-standard (NGS) techniques have been proposed to evaluate quantitative imaging methods using patient data. These techniques provide figures of merit (FoMs) quantifying the precision of the estimated quantitative value without requiring repeated measurements and without requiring a gold standard. However, applying these techniques to patient data presents several practical difficulties including assessing the underlying assumptions, accounting for patient-sampling-related uncertainty, and assessing the reliability of the estimated FoMs. To address these issues, we propose statistical tests that provide confidence in the underlying assumptions and in the reliability of the estimated FoMs. Furthermore, the NGS technique is integrated within a bootstrap-based methodology to account for patient-sampling-related uncertainty. The developed NGS framework was applied to evaluate four methods for segmenting lesions from F-Fluoro-2-deoxyglucose positron emission tomography images of patients with head-and-neck cancer on the task of precisely measuring the metabolic tumor volume. The NGS technique consistently predicted the same segmentation method as the most precise method. The proposed framework provided confidence in these results, even when gold-standard data were not available. The bootstrap-based methodology indicated improved performance of the NGS technique with larger numbers of patient studies, as was expected, and yielded consistent results as long as data from more than 80 lesions were available for the analysis. PMID:28331883

  9. 40 CFR 63.1296 - Standards for slabstock flexible polyurethane foam production-HAP ABA equipment leaks.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... polyurethane foam production-HAP ABA equipment leaks. 63.1296 Section 63.1296 Protection of Environment... Pollutants for Flexible Polyurethane Foam Production § 63.1296 Standards for slabstock flexible polyurethane foam production—HAP ABA equipment leaks. Each owner or operator of a new or existing slabstock affected...

  10. 40 CFR 63.1296 - Standards for slabstock flexible polyurethane foam production-HAP ABA equipment leaks.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... polyurethane foam production-HAP ABA equipment leaks. 63.1296 Section 63.1296 Protection of Environment... Pollutants for Flexible Polyurethane Foam Production § 63.1296 Standards for slabstock flexible polyurethane foam production—HAP ABA equipment leaks. Each owner or operator of a new or existing slabstock affected...

  11. When the value of gold is zero.

    PubMed

    Chase, J Geoffrey; Moeller, Knut; Shaw, Geoffrey M; Schranz, Christoph; Chiew, Yeong Shiong; Desaive, Thomas

    2014-06-27

    This manuscript presents the concerns around the increasingly common problem of not having readily available or useful "gold standard" measurements. This issue is particularly important in critical care where many measurements used in decision making are surrogates of what we would truly wish to use. However, the question is broad, important and applicable in many other areas.In particular, a gold standard measurement often exists, but is not clinically (or ethically in some cases) feasible. The question is how does one even begin to develop new measurements or surrogates if one has no gold standard to compare with?We raise this issue concisely with a specific example from mechanical ventilation, a core bread and butter therapy in critical care that is also a leading cause of length of stay and cost of care. Our proposed solution centers around a hierarchical validation approach that we believe would ameliorate ethics issues around radiation exposure that make current gold standard measures clinically infeasible, and thus provide a pathway to create a (new) gold standard.

  12. Building gold standard corpora for medical natural language processing tasks.

    PubMed

    Deleger, Louise; Li, Qi; Lingren, Todd; Kaiser, Megan; Molnar, Katalin; Stoutenborough, Laura; Kouril, Michal; Marsolo, Keith; Solti, Imre

    2012-01-01

    We present the construction of three annotated corpora to serve as gold standards for medical natural language processing (NLP) tasks. Clinical notes from the medical record, clinical trial announcements, and FDA drug labels are annotated. We report high inter-annotator agreements (overall F-measures between 0.8467 and 0.9176) for the annotation of Personal Health Information (PHI) elements for a de-identification task and of medications, diseases/disorders, and signs/symptoms for information extraction (IE) task. The annotated corpora of clinical trials and FDA labels will be publicly released and to facilitate translational NLP tasks that require cross-corpora interoperability (e.g. clinical trial eligibility screening) their annotation schemas are aligned with a large scale, NIH-funded clinical text annotation project.

  13. Gold-standard evaluation of a folksonomy-based ontology learning model

    NASA Astrophysics Data System (ADS)

    Djuana, E.

    2018-03-01

    Folksonomy, as one result of collaborative tagging process, has been acknowledged for its potential in improving categorization and searching of web resources. However, folksonomy contains ambiguities such as synonymy and polysemy as well as different abstractions or generality problem. To maximize its potential, some methods for associating tags of folksonomy with semantics and structural relationships have been proposed such as using ontology learning method. This paper evaluates our previous work in ontology learning according to gold-standard evaluation approach in comparison to a notable state-of-the-art work and several baselines. The results show that our method is comparable to the state-of the art work which further validate our approach as has been previously validated using task-based evaluation approach.

  14. Evaluating the Gold Standard: A Review and Meta-Analysis of the Structured Interview of Reported Symptoms

    ERIC Educational Resources Information Center

    Green, Debbie; Rosenfeld, Barry

    2011-01-01

    The Structured Interview of Reported Symptoms (SIRS; Rogers, Bagby, & Dickens, 1992) is often touted as the gold standard of measures of feigning. This label likely arises in part out of the impressive accuracy rates reported in the extensive validation research that preceded its publication. However, since its publication, researchers not only…

  15. 76 FR 70062 - Lifesaving Equipment: Production Testing and Harmonization With International Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-10

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard 46 CFR Parts 160, 180, and 199 [Docket No. USCG-2010-0048] RIN 1625-AB46 Lifesaving Equipment: Production Testing and Harmonization With International Standards Correction In rule document 2011-25035, appearing on pages 62962-63015 in the issue of Monday...

  16. 45 CFR 205.170 - State standards for office space, equipment, and facilities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false State standards for office space, equipment, and facilities. 205.170 Section 205.170 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN...

  17. 45 CFR 205.170 - State standards for office space, equipment, and facilities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false State standards for office space, equipment, and facilities. 205.170 Section 205.170 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN...

  18. 45 CFR 205.170 - State standards for office space, equipment, and facilities.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 2 2012-10-01 2012-10-01 false State standards for office space, equipment, and facilities. 205.170 Section 205.170 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN...

  19. 45 CFR 205.170 - State standards for office space, equipment, and facilities.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true State standards for office space, equipment, and facilities. 205.170 Section 205.170 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN...

  20. 45 CFR 205.170 - State standards for office space, equipment, and facilities.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 2 2014-10-01 2012-10-01 true State standards for office space, equipment, and facilities. 205.170 Section 205.170 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN...

  1. 77 FR 37733 - Technical Standard Order (TSO)-C68a, Airborne Automatic Dead Reckoning Computer Equipment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-22

    ..., Airborne Automatic Dead Reckoning Computer Equipment Utilizing Aircraft Heading and Doppler Ground Speed.... ACTION: Notice of intent to cancel Technical Standard Order (TSO)-C68a, Airborne automatic dead reckoning... dead reckoning computer equipment utilizing aircraft heading and Doppler ground speed and drift angle...

  2. 40 CFR 63.1298 - Standards for slabstock flexible polyurethane foam production-HAP emissions from equipment cleaning.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... polyurethane foam production-HAP emissions from equipment cleaning. 63.1298 Section 63.1298 Protection of... Hazardous Air Pollutants for Flexible Polyurethane Foam Production § 63.1298 Standards for slabstock flexible polyurethane foam production—HAP emissions from equipment cleaning. Each owner or operator of a...

  3. 40 CFR 63.1298 - Standards for slabstock flexible polyurethane foam production-HAP emissions from equipment cleaning.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... polyurethane foam production-HAP emissions from equipment cleaning. 63.1298 Section 63.1298 Protection of... Pollutants for Flexible Polyurethane Foam Production § 63.1298 Standards for slabstock flexible polyurethane foam production—HAP emissions from equipment cleaning. Each owner or operator of a new or existing...

  4. 40 CFR 63.1298 - Standards for slabstock flexible polyurethane foam production-HAP emissions from equipment cleaning.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... polyurethane foam production-HAP emissions from equipment cleaning. 63.1298 Section 63.1298 Protection of... Hazardous Air Pollutants for Flexible Polyurethane Foam Production § 63.1298 Standards for slabstock flexible polyurethane foam production—HAP emissions from equipment cleaning. Each owner or operator of a...

  5. 40 CFR 63.1298 - Standards for slabstock flexible polyurethane foam production-HAP emissions from equipment cleaning.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... polyurethane foam production-HAP emissions from equipment cleaning. 63.1298 Section 63.1298 Protection of... Pollutants for Flexible Polyurethane Foam Production § 63.1298 Standards for slabstock flexible polyurethane foam production—HAP emissions from equipment cleaning. Each owner or operator of a new or existing...

  6. 40 CFR 63.1298 - Standards for slabstock flexible polyurethane foam production-HAP emissions from equipment cleaning.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... polyurethane foam production-HAP emissions from equipment cleaning. 63.1298 Section 63.1298 Protection of... Pollutants for Flexible Polyurethane Foam Production § 63.1298 Standards for slabstock flexible polyurethane foam production—HAP emissions from equipment cleaning. Each owner or operator of a new or existing...

  7. Scattering resonances in bimolecular collisions between NO radicals and H2 challenge the theoretical gold standard

    NASA Astrophysics Data System (ADS)

    Vogels, Sjoerd N.; Karman, Tijs; Kłos, Jacek; Besemer, Matthieu; Onvlee, Jolijn; van der Avoird, Ad; Groenenboom, Gerrit C.; van de Meerakker, Sebastiaan Y. T.

    2018-02-01

    Over the last 25 years, the formalism known as coupled-cluster (CC) theory has emerged as the method of choice for the ab initio calculation of intermolecular interaction potentials. The implementation known as CCSD(T) is often referred to as the gold standard in quantum chemistry. It gives excellent agreement with experimental observations for a variety of energy-transfer processes in molecular collisions, and it is used to calibrate density functional theory. Here, we present measurements of low-energy collisions between NO radicals and H2 molecules with a resolution that challenges the most sophisticated quantum chemistry calculations at the CCSD(T) level. Using hitherto-unexplored anti-seeding techniques to reduce the collision energy in a crossed-beam inelastic-scattering experiment, a resonance structure near 14 cm-1 is clearly resolved in the state-to-state integral cross-section, and a unique resonance fingerprint is observed in the corresponding differential cross-section. This resonance structure discriminates between two NO-H2 potentials calculated at the CCSD(T) level and pushes the required accuracy beyond the gold standard.

  8. 40 CFR 63.5734 - What standards must I meet for resin and gel coat application equipment cleaning operations?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...? (a) For routine flushing of resin and gel coat application equipment (e.g., spray guns, flowcoaters... and gel coat application equipment cleaning operations? 63.5734 Section 63.5734 Protection of... Pollutants for Boat Manufacturing Standards for Resin and Gel Coat Application Equipment Cleaning Operations...

  9. 77 FR 23117 - Rigging Equipment for Material Handling Construction Standard; Correction and Technical Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-18

    ...OSHA is correcting its sling standard for construction titled ``Rigging Equipment for Material Handling'' by removing the rated capacity tables and making minor, nonsubstantive revisions to the regulatory text.

  10. 40 CFR Appendix B to Subpart B of... - Standard for Recover Equipment

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... process it to ARI (Air-Conditioning and Refrigeration Institute) standard 700-93 as a minimum. It is not... equipment capability is required which shall process contaminated refrigerant samples at specific... flare male thread connection as identified in SAE J639 CFC-12 High Pressure Charging Valve Figure 2. 6.3...

  11. 40 CFR Appendix B to Subpart B of... - Standard for Recover Equipment

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... process it to ARI (Air-Conditioning and Refrigeration Institute) standard 700-93 as a minimum. It is not... equipment capability is required which shall process contaminated refrigerant samples at specific... flare male thread connection as identified in SAE J639 CFC-12 High Pressure Charging Valve Figure 2. 6.3...

  12. 40 CFR Appendix B to Subpart B of... - Standard for Recover Equipment

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... process it to ARI (Air-Conditioning and Refrigeration Institute) standard 700-93 as a minimum. It is not... equipment capability is required which shall process contaminated refrigerant samples at specific... flare male thread connection as identified in SAE J639 CFC-12 High Pressure Charging Valve Figure 2. 6.3...

  13. 40 CFR Appendix B to Subpart B of... - Standard for Recover Equipment

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... process it to ARI (Air-Conditioning and Refrigeration Institute) standard 700-93 as a minimum. It is not... equipment capability is required which shall process contaminated refrigerant samples at specific... flare male thread connection as identified in SAE J639 CFC-12 High Pressure Charging Valve Figure 2. 6.3...

  14. 40 CFR Appendix B to Subpart B of... - Standard for Recover Equipment

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... process it to ARI (Air-Conditioning and Refrigeration Institute) standard 700-93 as a minimum. It is not... equipment capability is required which shall process contaminated refrigerant samples at specific... flare male thread connection as identified in SAE J639 CFC-12 High Pressure Charging Valve Figure 2. 6.3...

  15. 40 CFR 63.7920 - What emissions limitations and work practice standards must I meet for equipment leaks?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS... Pollutants: Site Remediation Equipment Leaks § 63.7920 What emissions limitations and work practice standards...

  16. 40 CFR 63.7920 - What emissions limitations and work practice standards must I meet for equipment leaks?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS... Pollutants: Site Remediation Equipment Leaks § 63.7920 What emissions limitations and work practice standards...

  17. 40 CFR 63.7920 - What emissions limitations and work practice standards must I meet for equipment leaks?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS... Pollutants: Site Remediation Equipment Leaks § 63.7920 What emissions limitations and work practice standards...

  18. 40 CFR 63.7920 - What emissions limitations and work practice standards must I meet for equipment leaks?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS... Pollutants: Site Remediation Equipment Leaks § 63.7920 What emissions limitations and work practice standards...

  19. 40 CFR 63.7920 - What emissions limitations and work practice standards must I meet for equipment leaks?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS... Pollutants: Site Remediation Equipment Leaks § 63.7920 What emissions limitations and work practice standards...

  20. Role of hydrogen ions in standard and activation heap leaching of gold

    NASA Astrophysics Data System (ADS)

    Rubtsov, YuI

    2017-02-01

    The role of hydrogen ions in activation heap leaching of gold from rebellious ore has been studied, which has allowed enhancing gold recovery. The author puts forward a gold leaching circuit with the use of activated oxygen-saturated solutions acidified to pH = 6-9.

  1. Farm Equipment Mechanic. Apprenticeship Training Standards = Mecanicien de machines agricoles. Normes de formation en apprentissage.

    ERIC Educational Resources Information Center

    Ontario Ministry of Skills Development, Toronto.

    These training standards for farm equipment mechanics are intended to be used by apprentice/trainees, instructors, and companies in Ontario, Canada, as a blueprint for training or as a prerequisite for accreditation/certification. The training standards identify skills required for this occupation and its related training program. They are…

  2. Renal biopsy practice: What is the gold standard?

    PubMed

    Brachemi, Soumeya; Bollée, Guillaume

    2014-11-06

    Renal biopsy (RB) is useful for diagnosis and therapy guidance of renal diseases but incurs a risk of bleeding complications of variable severity, from transitory haematuria or asymptomatic hematoma to life-threatening hemorrhage. Several risk factors for complications after RB have been identified, including high blood pressure, age, decreased renal function, obesity, anemia, low platelet count and hemostasis disorders. These should be carefully assessed and, whenever possible, corrected before the procedure. The incidence of serious complications has become low with the use of automated biopsy devices and ultrasound guidance, which is currently the "gold standard" procedure for percutaneous RB. An outpatient biopsy may be considered in a carefully selected population with no risk factor for bleeding. However, controversies persist on the duration of observation after biopsy, especially for native kidney biopsy. Transjugular RB and laparoscopic RB represent reliable alternatives to conventional percutaneous biopsy in patients at high risk of bleeding, although some factors limit their use. This aim of this review is to summarize the issues of complications after RB, assessment of hemorrhagic risk factors, optimal biopsy procedure and strategies aimed to minimize the risk of bleeding.

  3. An evaluation of the relative safety of U.S. mining explosion-protected equipment approval requirements versus international standards

    PubMed Central

    Calder, W.; Snyder, D.; Burr, J.F.

    2018-01-01

    This paper provides a determination of the equivalent level of protection of the international standards relative to similar criteria used by the U.S. Mine Safety and Health Administration (MSHA) to approve two-fault intrinsically safe (IS) stand-alone equipment. U.S. mining law requires such a determination for MSHA to use alternatives to existing standards. The primary issue is to demonstrate that the international standards for equipment evaluation will provide at least the same level of protection for miners as the document currently used by MSHA. PMID:29780219

  4. Assessment of gold and silver in assorted mobile phone printed circuit boards (PCBs): Original article.

    PubMed

    Vats, M C; Singh, S K

    2015-11-01

    Demand for gold and silver has been escalating with increasing usage of electronic equipment globally. Around 267.3 MT of gold and 7275 MT of silver are being consumed annually for manufacturing mobile phones, laptops and other electronic equipment. However, only 15% is recuperated from these equipment; the remainder lies in the storage yards or landfills. The waste comprise glass, plastics, wires, batteries, PCBs, metal casing, etc. The PCB is composed of precious metals, which creates immense purpose for recycling and recovery. This paper characterises and assesses the recoverable metallic fraction of gold and silver from PCBs of mobile phones. The methodology is based on dismantling of the mobile handset and subjecting the PCBs to roasting and acid digestion. The digested samples were analysed by atomic absorption spectroscopy and the content of gold and silver in the PCBs was to be found in the range of 0.009-0.017% and 0.25-0.79% by weight respectively. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. Gold recycling in the United States in 1998

    USGS Publications Warehouse

    Amey, Earle B.

    2001-01-01

    In 1998, 175 metric tons (t) of refined gold was recovered by U.S. refiners from old and new scrap. The overall recycling rate was 29 percent when scrap consumption was compared with apparent domestic supply. Sources of old scrap includes discarded jewelry, dental materials, plating solutions, and electronic equipment. A very high old scrap recycling efficiency of 96 percent was reached in 1998, the supply of old scrap peaked, gold prices were at an 18-year low, and substantial amounts of old scrap were exported. U.S. net exports of old scrap had a gold content of 28 t.

  6. Grading School Choice: Evaluating School Choice Programs by the Friedman Gold Standard. School Choice Issues in Depth

    ERIC Educational Resources Information Center

    Enlow, Robert C.

    2008-01-01

    In 2004, The Friedman Foundation for Educational Choice published a report titled "Grading Vouchers: Ranking America's School Choice Programs." Its purpose was to measure every existing school choice program against the gold standard set by Milton and Rose Friedman: that the most effective way to improve K-12 education and thus ensure a stable…

  7. [Investigation report on the technical standards of TCM diagnosis, treatment and rehabilitation equipment].

    PubMed

    Shen, Hua; Liu, Tangyi; Yang, Huayuan

    2016-02-01

    The questionnaire was adopted so as to investigate the attitudes and recognition of the manufacture eneprises of TCM diagnosis, treatment and rehabilitation equipment (DTRE) to the technical standards of, relevant products. It was found that the construction of the industrial standard and the national standard was lagged behind on TCM DTRE. Under the new situation, the enterprises are highly willing to participate in the development of the industrial, national and international standards and have a certain of understanding on the standard development. Nearly 80 % of enterprises believed that it was necessary to set up the relevant mirror organization for the development of industrial, national and international standard of TCM DITRE. In the future, the standard construction of TCM DTRE must face to the new situation. The constant increasing of the enterprises. and scientific research organizations in the standard construction must promote the development of TCM DTRE.

  8. A Gold Standards Approach to Training Instructors to Evaluate Crew Performance

    NASA Technical Reports Server (NTRS)

    Baker, David P.; Dismukes, R. Key

    2003-01-01

    The Advanced Qualification Program requires that airlines evaluate crew performance in Line Oriented Simulation. For this evaluation to be meaningful, instructors must observe relevant crew behaviors and evaluate those behaviors consistently and accurately against standards established by the airline. The airline industry has largely settled on an approach in which instructors evaluate crew performance on a series of event sets, using standardized grade sheets on which behaviors specific to event set are listed. Typically, new instructors are given a class in which they learn to use the grade sheets and practice evaluating crew performance observed on videotapes. These classes emphasize reliability, providing detailed instruction and practice in scoring so that all instructors within a given class will give similar scores to similar performance. This approach has value but also has important limitations; (1) ratings within one class of new instructors may differ from those of other classes; (2) ratings may not be driven primarily by the specific behaviors on which the company wanted the crews to be scored; and (3) ratings may not be calibrated to company standards for level of performance skill required. In this paper we provide a method to extend the existing method of training instructors to address these three limitations. We call this method the "gold standards" approach because it uses ratings from the company's most experienced instructors as the basis for training rater accuracy. This approach ties the training to the specific behaviors on which the experienced instructors based their ratings.

  9. Gold Standards,” Plurality and Monocultures: The Need for Diversity in Psychotherapy

    PubMed Central

    Leichsenring, Falk; Abbass, Allan; Hilsenroth, Mark J.; Luyten, Patrick; Munder, Thomas; Rabung, Sven; Steinert, Christiane

    2018-01-01

    For psychotherapy of mental disorders, presently several approaches are available, such as interpersonal, humanistic, systemic, psychodynamic or cognitive behavior therapy (CBT). Pointing to the available evidence, proponents of CBT claim that CBT is the gold standard. Some authors even argue for an integrated CBT-based form of psychotherapy as the only form of psychotherapy. CBT undoubtedly has its strengths and CBT researchers have to be credited for developing and testing treatments for many mental disorders. A critical review, however, shows that the available evidence for the theoretical foundations of CBT, assumed mechanisms of change, quality of studies, and efficacy is not as robust as some researchers claim. Most important, there is no consistent evidence that CBT is more efficacious than other evidence-based approaches. These findings do not justify regarding CBT as the gold standard psychotherapy. They even provide less justification for the idea that the future of psychotherapy lies in one integrated CBT-based form of psychotherapy as the only type of psychotherapy. For the different psychotherapeutic approaches a growing body of evidence is available. These approaches have their strengths because of differences in their respective focus on interpersonal relationships, affects, cognitions, systemic perspectives, experiential, or unconscious processes. Different approaches may be suitable to different patients and therapists. As generally assumed, progress in research results from openness to new ideas and learning from diverse perspectives. Thus, different forms of evidence-based psychotherapy are required. Plurality is the future of psychotherapy, not a uniform “one fits all” approach. PMID:29740361

  10. 76 FR 43941 - Energy Conservation Program: Energy Conservation Standards for Direct Heating Equipment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ... DEPARTMENT OF ENERGY 10 CFR Part 430 [Docket Number EERE-2011-BT-STD-0047] RIN 1904-AC56 Energy Conservation Program: Energy Conservation Standards for Direct Heating Equipment AGENCY: Office of Energy Efficiency and Renewable Energy, Department of Energy. ACTION: Notice of proposed rulemaking and announcement...

  11. 40 CFR 60.254 - Standards for coal processing and conveying equipment, coal storage systems, transfer and loading...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standards for coal processing and conveying equipment, coal storage systems, transfer and loading systems, and open storage piles. 60.254... (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of Performance for Coal Preparation...

  12. Detection of Echinococcus multilocularis by MC-PCR: evaluation of diagnostic sensitivity and specificity without gold standard

    PubMed Central

    Wahlström, Helene; Comin, Arianna; Isaksson, Mats; Deplazes, Peter

    2016-01-01

    Introduction A semi-automated magnetic capture probe-based DNA extraction and real-time PCR method (MC-PCR), allowing for a more efficient large-scale surveillance of Echinococcus multilocularis occurrence, has been developed. The test sensitivity has previously been evaluated using the sedimentation and counting technique (SCT) as a gold standard. However, as the sensitivity of the SCT is not 1, test characteristics of the MC-PCR was also evaluated using latent class analysis, a methodology not requiring a gold standard. Materials and methods Test results, MC-PCR and SCT, from a previous evaluation of the MC-PCR using 177 foxes shot in the spring (n=108) and autumn 2012 (n=69) in high prevalence areas in Switzerland were used. Latent class analysis was used to estimate the test characteristics of the MC-PCR. Although it is not the primary aim of this study, estimates of the test characteristics of the SCT were also obtained. Results and discussion This study showed that the sensitivity of the MC-PCR was 0.88 [95% posterior credible interval (PCI) 0.80–0.93], which was not significantly different than the SCT, 0.83 (95% PCI 0.76–0.88), which is currently considered as the gold standard. The specificity of both tests was high, 0.98 (95% PCI 0.94–0.99) for the MC-PCR and 0.99 (95% PCI 0.99–1) for the SCT. In a previous study, using fox scats from a low prevalence area, the specificity of the MC-PCR was higher, 0.999% (95% PCI 0.997–1). One reason for the lower estimate of the specificity in this study could be that the MC-PCR detects DNA from infected but non-infectious rodents eaten by foxes. When using MC-PCR in low prevalence areas or areas free from the parasite, a positive result in the MC-PCR should be regarded as a true positive. Conclusion The sensitivity of the MC-PCR (0.88) was comparable to the sensitivity of SCT (0.83). PMID:26968153

  13. Detection of Echinococcus multilocularis by MC-PCR: evaluation of diagnostic sensitivity and specificity without gold standard.

    PubMed

    Wahlström, Helene; Comin, Arianna; Isaksson, Mats; Deplazes, Peter

    2016-01-01

    A semi-automated magnetic capture probe-based DNA extraction and real-time PCR method (MC-PCR), allowing for a more efficient large-scale surveillance of Echinococcus multilocularis occurrence, has been developed. The test sensitivity has previously been evaluated using the sedimentation and counting technique (SCT) as a gold standard. However, as the sensitivity of the SCT is not 1, test characteristics of the MC-PCR was also evaluated using latent class analysis, a methodology not requiring a gold standard. Test results, MC-PCR and SCT, from a previous evaluation of the MC-PCR using 177 foxes shot in the spring (n=108) and autumn 2012 (n=69) in high prevalence areas in Switzerland were used. Latent class analysis was used to estimate the test characteristics of the MC-PCR. Although it is not the primary aim of this study, estimates of the test characteristics of the SCT were also obtained. This study showed that the sensitivity of the MC-PCR was 0.88 [95% posterior credible interval (PCI) 0.80-0.93], which was not significantly different than the SCT, 0.83 (95% PCI 0.76-0.88), which is currently considered as the gold standard. The specificity of both tests was high, 0.98 (95% PCI 0.94-0.99) for the MC-PCR and 0.99 (95% PCI 0.99-1) for the SCT. In a previous study, using fox scats from a low prevalence area, the specificity of the MC-PCR was higher, 0.999% (95% PCI 0.997-1). One reason for the lower estimate of the specificity in this study could be that the MC-PCR detects DNA from infected but non-infectious rodents eaten by foxes. When using MC-PCR in low prevalence areas or areas free from the parasite, a positive result in the MC-PCR should be regarded as a true positive. The sensitivity of the MC-PCR (0.88) was comparable to the sensitivity of SCT (0.83).

  14. Quantitative Rapid Assessment of Leukoaraiosis in CT : Comparison to Gold Standard MRI.

    PubMed

    Hanning, Uta; Sporns, Peter Bernhard; Schmidt, Rene; Niederstadt, Thomas; Minnerup, Jens; Bier, Georg; Knecht, Stefan; Kemmling, André

    2017-10-20

    The severity of white matter lesions (WML) is a risk factor of hemorrhage and predictor of clinical outcome after ischemic stroke; however, in contrast to magnetic resonance imaging (MRI) reliable quantification for this surrogate marker is limited for computed tomography (CT), the leading stroke imaging technique. We aimed to present and evaluate a CT-based automated rater-independent method for quantification of microangiopathic white matter changes. Patients with suspected minor stroke (National Institutes of Health Stroke scale, NIHSS < 4) were screened for the analysis of non-contrast computerized tomography (NCCT) at admission and compared to follow-up MRI. The MRI-based WML volume and visual Fazekas scores were assessed as the gold standard reference. We employed a recently published probabilistic brain segmentation algorithm for CT images to determine the tissue-specific density of WM space. All voxel-wise densities were quantified in WM space and weighted according to partial probabilistic WM content. The resulting mean weighted density of WM space in NCCT, the surrogate of WML, was correlated with reference to MRI-based WML parameters. The process of CT-based tissue-specific segmentation was reliable in 79 cases with varying severity of microangiopathy. Voxel-wise weighted density within WM spaces showed a noticeable correlation (r = -0.65) with MRI-based WML volume. Particularly in patients with moderate or severe lesion load according to the visual Fazekas score the algorithm provided reliable prediction of MRI-based WML volume. Automated observer-independent quantification of voxel-wise WM density in CT significantly correlates with microangiopathic WM disease in gold standard MRI. This rapid surrogate of white matter lesion load in CT may support objective WML assessment and therapeutic decision-making during acute stroke triage.

  15. Pre-Columbian alloys from the royal tombs of Sipán; energy dispersive X-ray fluorescence analysis with a portable equipment.

    PubMed

    Cesareo, R; Calza, C; Dos Anjos, M; Lopes, R T; Bustamante, A; Fabian S, J; Alva, W; Chero Z, L

    2010-01-01

    On the north coast of present-day Peru flourished approximately between 50 and 700 AD, the Moche civilization. It was an advanced culture and the Moche were sophisticated metalsmiths, so that they are considered as the finest producers of jewels and artefacts of the region. The Moche metalworking ability was impressively demonstrated by the objects discovered by Walter Alva and coworkers in 1987, in the excavations of the "Tumbas Reales de Sipán". About 50 metal objects from these excavations, now at the namesake Museum, in Lambayeque, north of Peru, were analyzed with a portable equipment using energy-dispersive X-ray fluorescence. This portable equipment is mainly composed of a small size X-ray tube and a thermoelectrically cooled X-ray detector. Standard samples of gold and silver alloys were employed for quantitative analysis. It was determined that the analyzed artefacts from the "Tumbas Reales de Sipán" are mainly composed of gold, silver and copper alloys, of gilded copper and of tumbaga, the last being a poor gold alloy enriched at the surface by depletion gilding, i.e. removing copper from the surface. Copyright 2009 Elsevier Ltd. All rights reserved.

  16. A no-gold-standard technique for objective assessment of quantitative nuclear-medicine imaging methods

    PubMed Central

    Jha, Abhinav K; Caffo, Brian; Frey, Eric C

    2016-01-01

    The objective optimization and evaluation of nuclear-medicine quantitative imaging methods using patient data is highly desirable but often hindered by the lack of a gold standard. Previously, a regression-without-truth (RWT) approach has been proposed for evaluating quantitative imaging methods in the absence of a gold standard, but this approach implicitly assumes that bounds on the distribution of true values are known. Several quantitative imaging methods in nuclear-medicine imaging measure parameters where these bounds are not known, such as the activity concentration in an organ or the volume of a tumor. We extended upon the RWT approach to develop a no-gold-standard (NGS) technique for objectively evaluating such quantitative nuclear-medicine imaging methods with patient data in the absence of any ground truth. Using the parameters estimated with the NGS technique, a figure of merit, the noise-to-slope ratio (NSR), can be computed, which can rank the methods on the basis of precision. An issue with NGS evaluation techniques is the requirement of a large number of patient studies. To reduce this requirement, the proposed method explored the use of multiple quantitative measurements from the same patient, such as the activity concentration values from different organs in the same patient. The proposed technique was evaluated using rigorous numerical experiments and using data from realistic simulation studies. The numerical experiments demonstrated that the NSR was estimated accurately using the proposed NGS technique when the bounds on the distribution of true values were not precisely known, thus serving as a very reliable metric for ranking the methods on the basis of precision. In the realistic simulation study, the NGS technique was used to rank reconstruction methods for quantitative single-photon emission computed tomography (SPECT) based on their performance on the task of estimating the mean activity concentration within a known volume of interest

  17. A no-gold-standard technique for objective assessment of quantitative nuclear-medicine imaging methods.

    PubMed

    Jha, Abhinav K; Caffo, Brian; Frey, Eric C

    2016-04-07

    The objective optimization and evaluation of nuclear-medicine quantitative imaging methods using patient data is highly desirable but often hindered by the lack of a gold standard. Previously, a regression-without-truth (RWT) approach has been proposed for evaluating quantitative imaging methods in the absence of a gold standard, but this approach implicitly assumes that bounds on the distribution of true values are known. Several quantitative imaging methods in nuclear-medicine imaging measure parameters where these bounds are not known, such as the activity concentration in an organ or the volume of a tumor. We extended upon the RWT approach to develop a no-gold-standard (NGS) technique for objectively evaluating such quantitative nuclear-medicine imaging methods with patient data in the absence of any ground truth. Using the parameters estimated with the NGS technique, a figure of merit, the noise-to-slope ratio (NSR), can be computed, which can rank the methods on the basis of precision. An issue with NGS evaluation techniques is the requirement of a large number of patient studies. To reduce this requirement, the proposed method explored the use of multiple quantitative measurements from the same patient, such as the activity concentration values from different organs in the same patient. The proposed technique was evaluated using rigorous numerical experiments and using data from realistic simulation studies. The numerical experiments demonstrated that the NSR was estimated accurately using the proposed NGS technique when the bounds on the distribution of true values were not precisely known, thus serving as a very reliable metric for ranking the methods on the basis of precision. In the realistic simulation study, the NGS technique was used to rank reconstruction methods for quantitative single-photon emission computed tomography (SPECT) based on their performance on the task of estimating the mean activity concentration within a known volume of interest

  18. 77 FR 6915 - Medical Diagnostic Equipment Accessibility Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-09

    ... Israel Deaconess Medical Center (October 22, 2009) accessible facilities and accessible medical equipment... of types of accessible medical equipment required in different types of health care facilities. If... facilities, accessible medical equipment, and auxiliary aids and services; University of Southern California...

  19. Gold-coated copper cone detector as a new standard detector for F2 laser radiation at 157 nm.

    PubMed

    Kück, Stefan; Brandt, Friedhelm; Taddeo, Mario

    2005-04-20

    A new standard detector for high-accuracy measurements of F2 laser radiation at 157 nm is presented. This gold-coated copper cone detector permits the measurement of average powers up to 2 W with an uncertainty of approximately 1%. To the best of our knowledge, this is the first highly accurate standard detector for F2 laser radiation for this power level. It is fully characterized according to Guide to the Expression of Uncertainty in Measurement of the International Organization for Standardization and is connected to the calibration chain for laser radiation established by the German National Metrology Institute.

  20. The interrupted serosubmucosal anastomosis - still the gold standard.

    PubMed

    Leslie, A; Steele, R J C

    2003-07-01

    The single-layer appositional serosubmucosal anastomosis is a well established technique and appears to have a favourable record. Over a 15-year period the senior author of this paper has performed or directly supervised 553 anastomoses using this technique. This report describes the results of these operations, the results of stapled anastomoses carried out during the same period and discusses the utility of the handsewn technique. From August 1986 to July 2001, 553 intestinal anastomoses in 550 patients were fashioned using single-layer, interrupted serosubmucosal 3/0 braided polyamide and 131 anastomoses in 131 patients were performed using a circular anastomosing stapler. One anastomotic leakage occurred in the group of patients whose anastomosis was handsewn (0.2%) and 11 leaks occurred in those who had a stapled anastomoses (8.4%). The mortality rate in each group was similar (2% and 2.3%, respectively). There were no deaths attributable to anastomotic dehiscence in either group. In this prospectively audited series of 553 handsewn anastomoses the leakage rate was 0.2%. These results compare favourably with other published series and continue to support a single layer of interrupted serosubmucosal sutures as the gold standard for anastomoses involving the large or small bowel.

  1. Assessing electronic health record phenotypes against gold-standard diagnostic criteria for diabetes mellitus.

    PubMed

    Spratt, Susan E; Pereira, Katherine; Granger, Bradi B; Batch, Bryan C; Phelan, Matthew; Pencina, Michael; Miranda, Marie Lynn; Boulware, Ebony; Lucas, Joseph E; Nelson, Charlotte L; Neely, Benjamin; Goldstein, Benjamin A; Barth, Pamela; Richesson, Rachel L; Riley, Isaretta L; Corsino, Leonor; McPeek Hinz, Eugenia R; Rusincovitch, Shelley; Green, Jennifer; Barton, Anna Beth; Kelley, Carly; Hyland, Kristen; Tang, Monica; Elliott, Amanda; Ruel, Ewa; Clark, Alexander; Mabrey, Melanie; Morrissey, Kay Lyn; Rao, Jyothi; Hong, Beatrice; Pierre-Louis, Marjorie; Kelly, Katherine; Jelesoff, Nicole

    2017-04-01

    We assessed the sensitivity and specificity of 8 electronic health record (EHR)-based phenotypes for diabetes mellitus against gold-standard American Diabetes Association (ADA) diagnostic criteria via chart review by clinical experts. We identified EHR-based diabetes phenotype definitions that were developed for various purposes by a variety of users, including academic medical centers, Medicare, the New York City Health Department, and pharmacy benefit managers. We applied these definitions to a sample of 173 503 patients with records in the Duke Health System Enterprise Data Warehouse and at least 1 visit over a 5-year period (2007-2011). Of these patients, 22 679 (13%) met the criteria of 1 or more of the selected diabetes phenotype definitions. A statistically balanced sample of these patients was selected for chart review by clinical experts to determine the presence or absence of type 2 diabetes in the sample. The sensitivity (62-94%) and specificity (95-99%) of EHR-based type 2 diabetes phenotypes (compared with the gold standard ADA criteria via chart review) varied depending on the component criteria and timing of observations and measurements. Researchers using EHR-based phenotype definitions should clearly specify the characteristics that comprise the definition, variations of ADA criteria, and how different phenotype definitions and components impact the patient populations retrieved and the intended application. Careful attention to phenotype definitions is critical if the promise of leveraging EHR data to improve individual and population health is to be fulfilled. © The Author 2016. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  2. Blinded sample size re-estimation in three-arm trials with 'gold standard' design.

    PubMed

    Mütze, Tobias; Friede, Tim

    2017-10-15

    In this article, we study blinded sample size re-estimation in the 'gold standard' design with internal pilot study for normally distributed outcomes. The 'gold standard' design is a three-arm clinical trial design that includes an active and a placebo control in addition to an experimental treatment. We focus on the absolute margin approach to hypothesis testing in three-arm trials at which the non-inferiority of the experimental treatment and the assay sensitivity are assessed by pairwise comparisons. We compare several blinded sample size re-estimation procedures in a simulation study assessing operating characteristics including power and type I error. We find that sample size re-estimation based on the popular one-sample variance estimator results in overpowered trials. Moreover, sample size re-estimation based on unbiased variance estimators such as the Xing-Ganju variance estimator results in underpowered trials, as it is expected because an overestimation of the variance and thus the sample size is in general required for the re-estimation procedure to eventually meet the target power. To overcome this problem, we propose an inflation factor for the sample size re-estimation with the Xing-Ganju variance estimator and show that this approach results in adequately powered trials. Because of favorable features of the Xing-Ganju variance estimator such as unbiasedness and a distribution independent of the group means, the inflation factor does not depend on the nuisance parameter and, therefore, can be calculated prior to a trial. Moreover, we prove that the sample size re-estimation based on the Xing-Ganju variance estimator does not bias the effect estimate. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  3. [The gold standard in diabetic foot treatment: total contact cast].

    PubMed

    Lozano-Platonoff, Adriana; Florida Mejía-Mendoza, Melissa Desireé; Ibáñez-Doria, Mónica; Contreras-Ruiz, José

    2014-01-01

    In patients with diabetes, foot complications remain one of the main health issues, with ulcers representing one of the most common. These ulcerations originate from repetitive trauma on a foot with neuropathy. Inadequate care of the diabetic foot may lead to one of the gravest complications of the diabetic foot: amputation. The key to the treatment of the diabetic foot is the control of comorbidities (glucose levels and vascular disease), debridement, exudate control with the available modern dressings, treatment of infection, and offloading the affected foot. A common error in this basic treatment is the method used for offloading, leading to delayed healing as a result, and maybe even amputation. For this purpose we propose the total contact cast considered the "gold standard" in diabetic foot offloading. The objective of the present review is to present the existing evidence in the medical literature on the effectiveness of its use for healing diabetic foot ulcers and hence preventing amputations.

  4. A novel 'Gold on Gold' biosensing scheme for an on-fiber immunoassay

    NASA Astrophysics Data System (ADS)

    Punjabi, N.; Satija, J.; Mukherji, S.

    2015-05-01

    In this paper, we propose a novel „gold on gold‟ biosensing scheme for absorbance based fiber-optic biosensor. First, a self-assembled monolayer of gold nanoparticles is formed at the sensing region of the fiber-optic probe by incubating an amino-silanized probe in a colloidal gold solution. Thereafter, the receptor moieties, i.e. Human immunoglobulin G (HIgG) were immobilized by using standard alkanethiol and classic carbodiimide coupling chemistry. Finally, biosensing experiments were performed with different concentrations of gold nanoparticle-tagged analyte, i.e. Goat anti- Human immunoglobulin G (Nanogold-GaHIgG). The sensor response was observed to be more than five-fold compared to the control bioassay, in which the sensor matrix was devoid of gold nanoparticle film. Also, the response was found to be ~10 times higher compared to the FITC-tagged scheme and ~14.5 times better compared to untagged scheme. This novel scheme also demonstrated the potential in improving the limit of detection for the fiber-optic biosensors.

  5. Study on Sumbawa gold recovery using centrifuge

    NASA Astrophysics Data System (ADS)

    Ferdana, A. D.; Petrus, H. T. B. M.; Bendiyasa, I. M.; Prijambada, I. D.; Hamada, F.; Sachiko, T.

    2018-01-01

    The Artisanal Small Gold Mining in Sumbawa has been processing gold with mercury (Hg), which poses a serious threat to the mining and global environment. One method of gold processing that does not use mercury is by gravity method. Before processing the ore first performed an analysis of Mineragraphy and analysis of compound with XRD. Mineragraphy results show that gold is associated with chalcopyrite and covelite and is a single particle (native) on size 58.8 μm, 117 μm up to 294 μm. characterization with XRD shows that the Sumbawa Gold Ore is composed of quartz, pyrite, pyroxene, and sericite compounds. Sentrifugation is one of separation equipment of gravity method to increase concentrate based on difference of specific gravity. The optimum concentration result is influenced by several variables, such as water flow rate and particle size. In this present research, the range of flow rate is 5 lpm and 10 lpm, the particle size - 100 + 200 mesh and -200 +300 mesh. Gold concentration in concentrate is measured by EDX. The result shows that the optimum condition is obtained at a separation with flow rate 5 lpm and a particle size of -100 + 200 mesh.

  6. Joint model for a diagnostic test without a gold standard in the presence of a dependent terminal event.

    PubMed

    Luo, Sheng; Su, Xiao; DeSantis, Stacia M; Huang, Xuelin; Yi, Min; Hunt, Kelly K

    2014-07-10

    Breast cancer patients after breast conservation therapy often develop ipsilateral breast tumor relapse (IBTR), whose classification (true local recurrence versus new ipsilateral primary tumor) is subject to error, and there is no available gold standard. Some patients may die because of breast cancer before IBTR develops. Because this terminal event may be related to the individual patient's unobserved disease status and time to IBTR, the terminal mechanism is non-ignorable. This article presents a joint analysis framework to model the binomial regression with misclassified binary outcome and the correlated time to IBTR, subject to a dependent terminal event and in the absence of a gold standard. Shared random effects are used to link together two survival times. The proposed approach is evaluated by a simulation study and is applied to a breast cancer data set consisting of 4477 breast cancer patients. The proposed joint model can be conveniently fit using adaptive Gaussian quadrature tools implemented in SAS 9.3 (SAS Institute Inc., Cary, NC, USA) procedure NLMIXED. Copyright © 2014 John Wiley & Sons, Ltd.

  7. Creating a Gold Standard for the Readability Measurement of Health Texts

    PubMed Central

    Kandula, Sasikiran; Zeng-Treitler, Qing

    2008-01-01

    Developing easy-to-read health texts for consumers continues to be a challenge in health communication. Though readability formulae such as Flesch-Kincaid Grade Level have been used in many studies, they were found to be inadequate to estimate the difficulty of some types of health texts. One impediment to the development of new readability assessment techniques is the absence of a gold standard that can be used to validate them. To overcome this deficiency, we have compiled a corpus of 324 health documents consisting of six different types of texts. These documents were manually reviewed and assigned a readability level (1-7 Likert scale) by a panel of five health literacy experts. The expert assigned ratings were found to be highly correlated with a patient representative’s readability ratings (r = 0.81, p<0.0001). PMID:18999150

  8. 40 CFR 63.1255 - Standards: Equipment leaks.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) Equipment that is in vacuum service is excluded from the requirements of this section. (9) Equipment that is... from the requirements of this section if it is identified as required in paragraph (g)(9) of this... paragraphs (c)(5) through (9) of this section. (ii) Leak definition. The instrument reading, as determined by...

  9. 40 CFR 63.1255 - Standards: Equipment leaks.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) Equipment that is in vacuum service is excluded from the requirements of this section. (9) Equipment that is... from the requirements of this section if it is identified as required in paragraph (g)(9) of this... paragraphs (c)(5) through (9) of this section. (ii) Leak definition. The instrument reading, as determined by...

  10. Web 2.0-Based Crowdsourcing for High-Quality Gold Standard Development in Clinical Natural Language Processing

    PubMed Central

    Deleger, Louise; Li, Qi; Kaiser, Megan; Stoutenborough, Laura

    2013-01-01

    Background A high-quality gold standard is vital for supervised, machine learning-based, clinical natural language processing (NLP) systems. In clinical NLP projects, expert annotators traditionally create the gold standard. However, traditional annotation is expensive and time-consuming. To reduce the cost of annotation, general NLP projects have turned to crowdsourcing based on Web 2.0 technology, which involves submitting smaller subtasks to a coordinated marketplace of workers on the Internet. Many studies have been conducted in the area of crowdsourcing, but only a few have focused on tasks in the general NLP field and only a handful in the biomedical domain, usually based upon very small pilot sample sizes. In addition, the quality of the crowdsourced biomedical NLP corpora were never exceptional when compared to traditionally-developed gold standards. The previously reported results on medical named entity annotation task showed a 0.68 F-measure based agreement between crowdsourced and traditionally-developed corpora. Objective Building upon previous work from the general crowdsourcing research, this study investigated the usability of crowdsourcing in the clinical NLP domain with special emphasis on achieving high agreement between crowdsourced and traditionally-developed corpora. Methods To build the gold standard for evaluating the crowdsourcing workers’ performance, 1042 clinical trial announcements (CTAs) from the ClinicalTrials.gov website were randomly selected and double annotated for medication names, medication types, and linked attributes. For the experiments, we used CrowdFlower, an Amazon Mechanical Turk-based crowdsourcing platform. We calculated sensitivity, precision, and F-measure to evaluate the quality of the crowd’s work and tested the statistical significance (P<.001, chi-square test) to detect differences between the crowdsourced and traditionally-developed annotations. Results The agreement between the crowd’s annotations and the

  11. The Tanzania experience: clinical laboratory testing harmonization and equipment standardization at different levels of a tiered health laboratory system.

    PubMed

    Massambu, Charles; Mwangi, Christina

    2009-06-01

    The rapid scale-up of the care and treatment programs in Tanzania during the preceding 4 years has greatly increased the demand for quality laboratory services for diagnosis of HIV and monitoring patients during antiretroviral therapy. Laboratory services were not in a position to cope with this demand owing to poor infrastructure, lack of human resources, erratic and/or lack of reagent supply and commodities, and slow manual technologies. With the limited human resources in the laboratory and the need for scaling up the care and treatment program, it became necessary to install automated equipment and train personnel for the increased volume of testing and new tests across all laboratory levels. With the numerous partners procuring equipment, the possibility of a multitude of equipment platforms with attendant challenges for procurement of reagents, maintenance of equipment, and quality assurance arose. Tanzania, therefore, had to harmonize laboratory tests and standardize laboratory equipment at different levels of the laboratory network. The process of harmonization of tests and standardization of equipment included assessment of laboratories, review of guidelines, development of a national laboratory operational plan, and stakeholder advocacy. This document outlines this process.

  12. Progression-free survival: gaining on overall survival as a gold standard and accelerating drug development.

    PubMed

    Lebwohl, David; Kay, Andrea; Berg, William; Baladi, Jean Francois; Zheng, Ji

    2009-01-01

    In clinical trials of oncology drugs, overall survival (OS) is a direct measure of clinical efficacy and is considered the gold standard primary efficacy end point. The purpose of this study was to discuss the difficulties in using OS as a primary efficacy end point in the setting of evolving cancer therapies. We suggest that progression-free survival is an appropriate efficacy end point in many types of cancer, specifically those for which OS is expected to be prolonged and for which subsequent treatments are expected to affect OS.

  13. 1968 Listing of Swimming Pool Equipment.

    ERIC Educational Resources Information Center

    National Sanitation Foundation, Ann Arbor, MI. Testing Lab.

    An up-to-date listing of swimming pool equipment including--(1) companies authorized to display the National Sanitation Foundation seal of approval, (2) equipment listed as meeting NSF swimming pool equipment standards relating to diatomite type filters, (3) equipment listed as meeting NSF swimming pool equipment standard relating to sand type…

  14. When do latent class models overstate accuracy for diagnostic and other classifiers in the absence of a gold standard?

    PubMed

    Spencer, Bruce D

    2012-06-01

    Latent class models are increasingly used to assess the accuracy of medical diagnostic tests and other classifications when no gold standard is available and the true state is unknown. When the latent class is treated as the true class, the latent class models provide measures of components of accuracy including specificity and sensitivity and their complements, type I and type II error rates. The error rates according to the latent class model differ from the true error rates, however, and empirical comparisons with a gold standard suggest the true error rates often are larger. We investigate conditions under which the true type I and type II error rates are larger than those provided by the latent class models. Results from Uebersax (1988, Psychological Bulletin 104, 405-416) are extended to accommodate random effects and covariates affecting the responses. The results are important for interpreting the results of latent class analyses. An error decomposition is presented that incorporates an error component from invalidity of the latent class model. © 2011, The International Biometric Society.

  15. 40 CFR 63.1296 - Standards for slabstock flexible polyurethane foam production-HAP ABA equipment leaks.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... polyurethane foam production-HAP ABA equipment leaks. 63.1296 Section 63.1296 Protection of Environment... Flexible Polyurethane Foam Production § 63.1296 Standards for slabstock flexible polyurethane foam... emissions from leaks from transfer pumps, valves, connectors, pressure-relief valves, and open-ended lines...

  16. 40 CFR 63.1296 - Standards for slabstock flexible polyurethane foam production-HAP ABA equipment leaks.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... polyurethane foam production-HAP ABA equipment leaks. 63.1296 Section 63.1296 Protection of Environment... Flexible Polyurethane Foam Production § 63.1296 Standards for slabstock flexible polyurethane foam... emissions from leaks from transfer pumps, valves, connectors, pressure-relief valves, and open-ended lines...

  17. 40 CFR 63.1296 - Standards for slabstock flexible polyurethane foam production-HAP ABA equipment leaks.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... polyurethane foam production-HAP ABA equipment leaks. 63.1296 Section 63.1296 Protection of Environment... Flexible Polyurethane Foam Production § 63.1296 Standards for slabstock flexible polyurethane foam... emissions from leaks from transfer pumps, valves, connectors, pressure-relief valves, and open-ended lines...

  18. Standards for material handling and facilities equipment proofload testing

    NASA Technical Reports Server (NTRS)

    Bonn, S. P.

    1970-01-01

    Document provides information on verifying the safety of material handling and facilities equipment /MH/FE/, ranging from monorail systems to ladders and non-powered mobile equipment. Seven catagories of MH/FE equipment are defined.

  19. Reverse translated and gold standard continuous performance tests predict global cognitive performance in schizophrenia.

    PubMed

    Bismark, Andrew W; Thomas, Michael L; Tarasenko, Melissa; Shiluk, Alexandra L; Rackelmann, Sonia Y; Young, Jared W; Light, Gregory A

    2018-04-12

    Attentional dysfunction contributes to functional impairments in schizophrenia (SZ). Sustained attention is typically assessed via continuous performance tasks (CPTs), though many CPTs have limited cross-species translational validity and place demands on additional cognitive domains. A reverse-translated 5-Choice Continuous Performance Task (5C-CPT) for human testing-originally developed for use in rodents-was designed to minimize demands on perceptual, visual learning, processing speed, or working memory functions. To-date, no studies have validated the 5C-CPT against gold standard attentional measures nor evaluated how 5C-CPT scores relate to cognition in SZ. Here we examined the relationship between the 5C-CPT and the CPT-Identical Pairs (CPT-IP), an established and psychometrically robust measure of vigilance from the MATRICS Consensus Cognitive Battery (MCCB) in a sample of SZ patients (n = 35). Relationships to global and individual subdomains of cognition were also assessed. 5C-CPT and CPT-IP measures of performance (d-prime) were strongly correlated (r = 0.60). In a regression model, the 5C-CPT and CPT-IP collectively accounted for 54% of the total variance in MCCB total scores, and 27.6% of overall cognitive variance was shared between the 5C-CPT and CPT-IP. These results indicate that the reverse translated 5C-CPT and the gold standard CPT-IP index a common attentional construct that also significantly overlaps with variance in general cognitive performance. The use of simple, cross-species validated behavioral indices of attentional/cognitive functioning such as the 5C-CPT could accelerate the development of novel generalized pro-cognitive therapeutics for SZ and related neuropsychiatric disorders.

  20. GEMINI-TITAN (GT)-8 - EXTRAVEHICULAR (EV) EQUIPMENT & SUIT - MSC

    NASA Image and Video Library

    1966-01-18

    S66-17475 (18 Jan. 1966) --- Test subject Fred Spress, Crew Systems Division, wears the spacesuit and extravehicular equipment planned for use by astronaut David R. Scott. The helmet is equipped with a gold-plated visor to shield the astronaut's face from unfiltered sun rays. The system is composed of a life support pack worn on the chest and a support pack worn on the back. Photo credit: NASA

  1. GEMINI-TITAN (GT)-8 - EXTRAVEHICULAR (EV) EQUIPMENT & SUIT - MSC

    NASA Image and Video Library

    1966-01-18

    S66-17480 (18 Jan. 1966) --- Test subject Fred Spress, Crew Systems Division, wears the spacesuit and extravehicular equipment planned for use by astronaut David R. Scott. The helmet is equipped with a gold-plated visor to shield the astronaut's face from unfiltered sun rays. The system is composed of a life support pack worn on the chest and a support pack worn on the back. Photo credit: NASA

  2. NAEP: Gold Standard or Fool's Gold?

    ERIC Educational Resources Information Center

    Popham, W. James

    2005-01-01

    Results of tests of students' skills and knowledge conducted by the National Assessment of Educational Progress (NAEP) and the state accountability tests required by the No Child Left Behind (NCLB) program should not be compared. The two tests are based on different standards and have different measurement functions and judging the results of one…

  3. Immobilization of gold nanoparticles on cell culture surfaces for safe and enhanced gold nanoparticle-mediated laser transfection.

    PubMed

    Kalies, Stefan; Heinemann, Dag; Schomaker, Markus; Gentemann, Lara; Meyer, Heiko; Ripken, Tammo

    2014-01-01

    In comparison to standard transfection methods, gold nanoparticle-mediated laser transfection has proven to be a versatile alternative. This is based on its minor influence on cell viability and its high efficiency, especially for the delivery of small molecules like small interfering RNA. However, in order to transfer it to routine usage, a safety aspect is of major concern: The avoidance of nanoparticle uptake by the cells is desired. The immobilization of the gold nanoparticles on cell culture surfaces can address this issue. In this study, we achieved this by silanization of the appropriate surfaces and the binding of gold nanoparticles to them. Comparable perforation efficiencies to the previous approaches of gold nanoparticle-mediated laser transfection with free gold nanoparticles are demonstrated. The uptake of the immobilized particles by the cells is unlikely. Consequently, these investigations offer the possibility of bringing gold nanoparticle-mediated laser transfection closer to routine usage.

  4. Decision Making in the Management of Extracapsular Fractures of the Proximal Femur - is the Dynamic Hip Screw the Prevailing Gold Standard?

    PubMed

    Jacob, Joshua; Desai, Ankit; Trompeter, Alex

    2017-01-01

    Currently, approximately half of all hip fractures are extracapsular, with an incidence as high as 50 in 100,000 in some countries. The common classification systems fail to explain the logistics of fracture classification and whether they all behave in the same manner. The Muller AO classification system is a useful platform to delineate stable and unstable fractures. The Dynamic hip screw (DHS) however, has remained the 'gold standard' implant of choice for application in all extracapsular fractures. The DHS relies on the integrity and strength of the lateral femoral wall as well as the postero-medial fragment. An analysis of several studies indicates significant improvements in design and techniques to ensure a better outcome with intramedullary nails. This article reviews the historical trends that helped to evolve the DHS implant as well as discussing if the surgeon should remain content with this implant. We suggest that the gold standard surgical management of extracapsular fractures can, and should, evolve.

  5. Can We Create a "Gold Standard of Education" for Our Children through the "Advancement via Independent Determination (AVID) Program"?

    ERIC Educational Resources Information Center

    Gaskins, Darlene

    2014-01-01

    We need to come together as a team and become one system of total quality improvement regarding the education of our nation's children. In order to achieve a gold standard in the education of our nation's children, leadership has to be willing to go against the status quo and build bridges for long-term sustainable change. In order to survive,…

  6. ADJUSTABLE OUTPUT RATE CHEMICAL FEEDING EQUIPMENT FOR SWIMMING POOLS. NATIONAL SANITATION FOUNDATION STANDARD NUMBER 19.

    ERIC Educational Resources Information Center

    National Sanitation Foundation, Ann Arbor, MI.

    THE SCOPE OF THIS STANDARD COVERS ADJUSTABLE OUTPUT RATE CHEMICAL FEEDERS, WHETHER USED FOR SOLUTIONS, SLURRIES OR SOLIDS. IT ALSO INCLUDES AUXILIARY EQUIPMENT SUCH AS PUMPS, STRAINERS, TUBING CONNECTIONS, TANKS, INJECTION FITTINGS AND OTHER REQUIRED COMPONENTS. THE FEEDERS DESCRIBED ARE INTENDED TO BE DESIGNED AND USED SPECIFICALLY FOR CHEMICAL…

  7. 40 CFR Appendix E to Subpart B of... - The Standard for Automotive Refrigerant Recycling Equipment Intended for Use With Both CFC-12 and...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Refrigerant Recycling Equipment Intended for Use With Both CFC-12 and HFC-134a E Appendix E to Subpart B of... Appendix E to Subpart B of Part 82—The Standard for Automotive Refrigerant Recycling Equipment Intended for... specific minimum equipment requirements for automotive refrigerant recycling equipment intended for use...

  8. 40 CFR Appendix E to Subpart B of... - The Standard for Automotive Refrigerant Recycling Equipment Intended for Use With Both CFC-12 and...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Refrigerant Recycling Equipment Intended for Use With Both CFC-12 and HFC-134a E Appendix E to Subpart B of... Appendix E to Subpart B of Part 82—The Standard for Automotive Refrigerant Recycling Equipment Intended for... specific minimum equipment requirements for automotive refrigerant recycling equipment intended for use...

  9. 40 CFR Appendix E to Subpart B of... - The Standard for Automotive Refrigerant Recycling Equipment Intended for Use With Both CFC-12 and...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Refrigerant Recycling Equipment Intended for Use With Both CFC-12 and HFC-134a E Appendix E to Subpart B of... Appendix E to Subpart B of Part 82—The Standard for Automotive Refrigerant Recycling Equipment Intended for... specific minimum equipment requirements for automotive refrigerant recycling equipment intended for use...

  10. 40 CFR Appendix E to Subpart B of... - The Standard for Automotive Refrigerant Recycling Equipment Intended for Use With Both CFC-12 and...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Refrigerant Recycling Equipment Intended for Use With Both CFC-12 and HFC-134a E Appendix E to Subpart B of... Appendix E to Subpart B of Part 82—The Standard for Automotive Refrigerant Recycling Equipment Intended for... specific minimum equipment requirements for automotive refrigerant recycling equipment intended for use...

  11. Gold Standard Tests

    DTIC Science & Technology

    2001-06-01

    important issues need to be understood. Caloric Irrigation: Irrigation of both ears with water of 30 and 44 degree Celsius is the standard Anamnesis ... anamnesis , falls short. In the usual because there are many factors which may clinical situation, a vestibular deficit is suspected if influence the final

  12. Airside HVAC BESTEST. Adaptation of ASHRAE RP 865 Airside HVAC Equipment Modeling Test Cases for ASHRAE Standard 140. Volume 1, Cases AE101-AE445

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Neymark, J.; Kennedy, M.; Judkoff, R.

    This report documents a set of diagnostic analytical verification cases for testing the ability of whole building simulation software to model the air distribution side of typical heating, ventilating and air conditioning (HVAC) equipment. These cases complement the unitary equipment cases included in American National Standards Institute (ANSI)/American Society of Heating, Refrigerating, and Air-Conditioning Engineers (ASHRAE) Standard 140, Standard Method of Test for the Evaluation of Building Energy Analysis Computer Programs, which test the ability to model the heat-transfer fluid side of HVAC equipment.

  13. Paralympic sports medicine--current evidence in winter sport: considerations in the development of equipment standards for paralympic athletes.

    PubMed

    Burkett, Brendan

    2012-01-01

    To highlight and discuss the considerations for the future development of equipment standards for Winter Paralympic sports. Literature searches were performed (in English) during May 2011 using the key words "technology, winter sport, Olympic, and Paralympic" in the computerized databases PubMed, PsycINFO, Science Direct, and Google Scholar. In addition, personal scientific observations were made at several Winter Paralympic Games. The retrieved articles were screened and assessed for relevance to the biological, biomechanical, and sport medicine aspects of equipment. There are 3 key areas in which technology has influenced sports performance in Paralympic winter sports, namely, specialized prostheses, crutch skis or outriggers (in lieu of poles), and sport-specific wheelchairs (such as the sit-ski). From a sport medicine perspective, a crucial factor not considered in the standard laboratory test of mechanical efficiency is the influence of the human-equipment connection, such as the stump-to-prosthesis interface or the required human-to-wheelchair control. This connectivity is critical to the effective operation of the assistive device. When assessing the efficiency of this equipment, the not-so-obvious, holistic, compensatory factors need to be considered. Assistive equipment is fundamental for a person with a disability to participate and compete in winter sport activities. Although there have been improvements in the mechanical function of some assistive devices, the key issue is matching the residual function of the person with the assistive equipment. Equitable access to this technology will also ensure that the fundamental spirit of fair play that underpins the Paralympic Games is maintained.

  14. Paving the way for a gold standard of care for infertility treatment: improving outcomes through standardization of laboratory procedures.

    PubMed

    Schoolcraft, William; Meseguer, Marcos

    2017-10-01

    Infertility affects over 70 million couples globally. Access to, and interest in, assisted reproductive technologies is growing worldwide, with more couples seeking medical intervention to conceive, in particular by IVF. Despite numerous advances in IVF techniques since its first success in 1978, almost half of the patients treated remain childless. The multifactorial nature of IVF treatment means that success is dependent on many variables. Therefore, it is important to examine how each variable can be optimized to achieve the best possible outcomes for patients. The current approach to IVF is fragmented, with various protocols in use. A systematic approach to establishing optimum best practices may improve IVF success and live birth rates. Our vision of the future is that technological advancements in the laboratory setting are standardized and universally adopted to enable a gold standard of care. Implementation of best practices for laboratory procedures will enable clinicians to generate high-quality gametes, and to produce and identify gametes and embryos of maximum viability and implantation potential, which should contribute to improving take-home healthy baby rates. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  15. 40 CFR 63.7922 - How do I demonstrate continuous compliance with the work practice standards for equipment leaks?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS... Hazardous Air Pollutants: Site Remediation Equipment Leaks § 63.7922 How do I demonstrate continuous...

  16. 40 CFR 63.7922 - How do I demonstrate continuous compliance with the work practice standards for equipment leaks?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS... Hazardous Air Pollutants: Site Remediation Equipment Leaks § 63.7922 How do I demonstrate continuous...

  17. 40 CFR 63.7922 - How do I demonstrate continuous compliance with the work practice standards for equipment leaks?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS... Hazardous Air Pollutants: Site Remediation Equipment Leaks § 63.7922 How do I demonstrate continuous...

  18. 40 CFR 63.7922 - How do I demonstrate continuous compliance with the work practice standards for equipment leaks?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS... Hazardous Air Pollutants: Site Remediation Equipment Leaks § 63.7922 How do I demonstrate continuous...

  19. 40 CFR 63.7922 - How do I demonstrate continuous compliance with the work practice standards for equipment leaks?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS... Hazardous Air Pollutants: Site Remediation Equipment Leaks § 63.7922 How do I demonstrate continuous...

  20. 77 FR 53962 - Technical Standard Order (TSO)-C68a, Airborne Automatic Dead Reckoning Computer Equipment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-04

    ..., Airborne Automatic Dead Reckoning Computer Equipment Utilizing Aircraft Heading and Doppler Ground Speed.... ACTION: Notice of cancellation of Technical Standard Order (TSO)-C68a, Airborne Automatic Dead Reckoning... . SUPPLEMENTARY INFORMATION: Background Doppler radar is a semiautomatic self-contained dead reckoning navigation...

  1. 40 CFR 63.1363 - Standards for equipment leaks.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) Equipment that is in vacuum service is excluded from the requirements of this section. (9) Equipment that is... from the requirements of this section if it is identified as required in paragraph (g)(9) of this..., 63.178, paragraph (f) of this section, and paragraphs (c)(5) through (9) of this section. (ii) Leak...

  2. Plasmonic gold nanoparticles for detection of fungi and human cutaneous fungal infections.

    PubMed

    Sojinrin, Tobiloba; Conde, João; Liu, Kangze; Curtin, James; Byrne, Hugh J; Cui, Daxiang; Tian, Furong

    2017-07-01

    Fungi, which are common in the environment, can cause a multitude of diseases. Warm, humid conditions allow fungi to grow and infect humans via the respiratory, digestive and reproductive tracts, genital area and other bodily interfaces. Fungi can be detected directly by microscopy, using the potassium hydroxide test, which is the gold standard and most popular method for fungal screening. However, this test requires trained personnel operating specialist equipment, including a fluorescent microscope and culture facilities. As most acutely infected patients seek medical attention within the first few days of symptoms, the optimal diagnostic test would be rapid and self-diagnostic simplifying and improving the therapeutic outcome. In suspensions of gold nanoparticles, Aspergillus niger can cause a colour change from red to blue within 2 min, as a result of changes in nanoparticle shape. A similar colour change was observed in the supernatant of samples of human toenails dispersed in water. Scanning electron microscopy, UV/Vis and Raman spectroscopy were employed to monitor the changes in morphology and surface plasmon resonance of the nanoparticles. The correlation of colour change with the fungal infection was analysed using the absorbance ratio at 520 nm/620 nm. We found a decrease in the ratio when the fungi concentration increased from 1 to 16 CFU/mL, with a detection limit of 10 CFU/mL. The test had an 80% sensitivity and a 95% specificity value for the diagnosis of athlete's foot in human patients. This plasmonic gold nanoparticle-based system for detection of fungal infections measures the change in shape of gold nanoparticles and generates coloured solutions with distinct tonality. Our application has the potential to contribute to self-diagnosis and hygiene control in laboratories/hospitals with fewer resources, just using the naked eye. Graphical abstract Colorimetric method for fungi detection with gold nano particles.

  3. Listing of Food Service Equipment.

    ERIC Educational Resources Information Center

    National Sanitation Foundation, Ann Arbor, MI. Testing Lab.

    A comprehensive listing of food service equipment including--(1) companies authorized to use the National Sanitation Foundation seal of approval, and (2) equipment listed as meeting NSF standards including soda fountains, spray-type dishwashers, dishwashing equipment, cooking equipment, commerical cooking and warming equipment, freezers,…

  4. Site-Specific Attachment of gold Nanoparticles to DNA Templates

    DTIC Science & Technology

    2001-01-01

    1 -ethyl- 3 -( 3 - dimethylaminopropyl ) carbodiimide hydrochloride (Pierce) and -2.0rmg N...functionalized gold nanoparticles. The gold particles were covalently bound to the amino groups on the DNA using standard 1 -ethyl- 3 - ( 3 - dimethylaminopropyl ...nm). The reaction between the amino group on the DNA and the carboxyl group on the gold particle was facilitated by 1 -ethyl- 3 -( 3 - dimethylaminopropyl

  5. Proposed Rule for Amendments Related to: Tier 3 Motor Vehicle Emission and Fuel Standards, Nonroad Engine and Equipment

    EPA Pesticide Factsheets

    Link to Federal Register Notice from February 19, 2015 announcing Amendments Related to: Tier 3 Motor Vehicle Emission and Fuel Standards, Nonroad Engine and Equipment Programs, and MARPOL Annex VI Implementation.

  6. Low-cost mercury (II) ion sensor by biosynthesized gold nanoparticles (AuNPs)

    NASA Astrophysics Data System (ADS)

    Guerrero, Jet G.; Candano, Gabrielle Jackie; Mendoza, Aileen Nicole; Paderanga, Marciella; Cardino, Krenz John; Locsin, Alessandro; Bibon, Cherilou

    2017-11-01

    Biosynthesis of gold nanoparticles has attracted the curiosity of scientists over the past few decades. Nanoparticles have been proven to exhibit enhanced properties and offer a variety of applications in different fields of study. Utilizing nanoparticles instead of bulky equipment and noxious chemicals has become more convenient; reagents needed for synthesis have been proven to be benign (mostly aqueous solutions) and are cost-effective. In this study, gold nanoparticles were biosynthesized using guyabano (Annonamuricata) peel samples as the source of reducing agents. The optimum concentration ratio of gold chloride to guyabano extract was determined to be 1:7. Characterization studies were accomplished using UV Vis Spectroscopy, Fourier Transform Electron Microscopy (FTIR) and Scanning Electron Microscopy (SEM). Spectroscopic maximum absorbance was found to be at 532 nm thereby confirming the presence of gold nanoparticles. Hydroxyl (O-H stretching), carbonyl (C=O stretching), and amide (N-H stretching) functional groups shown in the FTIR spectra are present on possible reducing agents such as phenols, alkaloids, and saponins found in the plant extract. SEM images revealed spherical shaped nanoparticles with mean diameter of 23.18 nm. It was observed that the bio-synthesized AuNPs were selective to mercury ions through uniform color change from wine red to yellow. A novel smartphone-based mercury (II) ions assay was developed using the gold nanoparticles. A calibration curve correlated the analytical response (Red intensity) to the concentrations of Hg 2+ ions. Around 94% of the variations in the intensity is accounted for by the variations in the concentration of mercury (II) ions suggesting a good linear relationship between the two variables. A relative standard deviation (RSD) of less than 1% was achieved at all individual points. The metal sensor displayed a sensitivity of 0.039 R.I./ppm with an LOD of 93.79 ppm. Thus, the bio-fabricated gold nanoparticles

  7. NASA researchers in gold control room during an F-15 HiDEC flight

    NASA Technical Reports Server (NTRS)

    1993-01-01

    NASA researchers monitor equipment in the mission control Gold room at the Dryden Flight Research Center, Edwards, California, during a flight of an F-15 Highly Integrated Digital Electronic Control (HIDEC) research aircraft. The system was developed on the F-15 to investigate and demonstrate methods of obtaining optimum aircraft performance. The major elements of HIDEC were a Digital Electronic Flight Control System (DEFCS), a Digital Electronic Engine Control (DEEC), an on-board general purpose computer, and an integrated architecture to allow all components to 'talk to each other.' Unlike standard F-15s, which have a mechanical and analog electronic flight control system, the HIDEC F-15 also had a dual-channel, fail-safe digital flight control system programmed in Pascal. It was linked to the Military Standard 1553B and a H009 data bus which tied all the other electronic systems together.

  8. Evaluation of the Performance of Five Diagnostic Tests for Fasciola hepatica Infection in Naturally Infected Cattle Using a Bayesian No Gold Standard Approach.

    PubMed

    Mazeri, Stella; Sargison, Neil; Kelly, Robert F; Bronsvoort, Barend M deC; Handel, Ian

    2016-01-01

    The clinical and economic importance of fasciolosis has been recognised for centuries, yet diagnostic tests available for cattle are far from perfect. Test evaluation has mainly been carried out using gold standard approaches or under experimental settings, the limitations of which are well known. In this study, a Bayesian no gold standard approach was used to estimate the diagnostic sensitivity and specificity of five tests for fasciolosis in cattle. These included detailed liver necropsy including gall bladder egg count, faecal egg counting, a commercially available copro-antigen ELISA, an in-house serum excretory/secretory antibody ELISA and routine abattoir liver inspection. In total 619 cattle slaughtered at one of Scotland's biggest abattoirs were sampled, during three sampling periods spanning summer 2013, winter 2014 and autumn 2014. Test sensitivities and specificities were estimated using an extension of the Hui Walter no gold standard model, where estimates were allowed to vary between seasons if tests were a priori believed to perform differently for any reason. The results of this analysis provide novel information on the performance of these tests in a naturally infected cattle population and at different times of the year where different levels of acute or chronic infection are expected. Accurate estimates of sensitivity and specificity will allow for routine abattoir liver inspection to be used as a tool for monitoring the epidemiology of F. hepatica as well as evaluating herd health planning. Furthermore, the results provide evidence to suggest that the copro-antigen ELISA does not cross-react with Calicophoron daubneyi rumen fluke parasites, while the serum antibody ELISA does.

  9. Flameless atomic-absorption determination of gold in geological materials

    USGS Publications Warehouse

    Meier, A.L.

    1980-01-01

    Gold in geologic material is dissolved using a solution of hydrobromic acid and bromine, extracted with methyl isobutyl ketone, and determined using an atomic-absorption spectrophotometer equipped with a graphite furnace atomizer. A comparison of results obtained by this flameless atomic-absorption method on U.S. Geological Survey reference rocks and geochemical samples with reported values and with results obtained by flame atomic-absorption shows that reasonable accuracy is achieved with improved precision. The sensitivity, accuracy, and precision of the method allows acquisition of data on the distribution of gold at or below its crustal abundance. ?? 1980.

  10. Cost Comparison of Fundamentals of Laparoscopic Surgery Training Completed With Standard Fundamentals of Laparoscopic Surgery Equipment versus Low-Cost Equipment.

    PubMed

    Franklin, Brenton R; Placek, Sarah B; Wagner, Mercy D; Haviland, Sarah M; O'Donnell, Mary T; Ritter, E Matthew

    Training for the Fundamentals of Laparoscopic Surgery (FLS) skills test can be expensive. Previous work demonstrated that training on an ergonomically different, low-cost platform does not affect FLS skills test outcomes. This study compares the average training cost with standard FLS equipment and medical-grade consumables versus training on a lower cost platform with non-medical-grade consumables. Subjects were prospectively randomized to either the standard FLS training platform (n = 19) with medical-grade consumables (S-FLS), or the low-cost platform (n = 20) with training-grade products (LC-FLS). Both groups trained to proficiency using previously established mastery learning standards on the 5 FLS tasks. The fixed and consumable cost differences were compared. Training occurred in a surgical simulation center. Laparoscopic novice medical student and resident physician health care professionals who had not completed the national FLS proficiency curriculum and who had performed less than 10 laparoscopic cases. The fixed cost of the platform was considerably higher in the S-FLS group (S-FLS, $3360; LC-FLS, $879), and the average consumable training cost was significantly higher for the S-FLS group (S-FLS, $1384.52; LC-FLS, $153.79; p < 0.001). The LC-FLS group had a statistically discernable cost reduction for each consumable (Gauze $9.24 vs. $0.39, p = 0.002; EndoLoop $540.00 vs. $40.60, p < 0.001; extracorporeal suture $216.45 vs. $25.20, p < 0.001; intracorporeal suture $618.83 vs. $87.60, p < 0.001). The annual fixed and consumable cost to train 5 residents is $10,282.60 in the S-FLS group versus $1647.95 in the LC-FLS group. This study shows that the average cost to train a single trainee to proficiency using a lower fixed-cost platform and non-medical-grade equipment results in significant financial savings. A 5-resident program will save approximately $8500 annually. Residency programs should consider adopting this strategy to reduce the cost of FLS

  11. Selection of emission factor standards for estimating emissions from diesel construction equipment in building construction in the Australian context.

    PubMed

    Zhang, Guomin; Sandanayake, Malindu; Setunge, Sujeeva; Li, Chunqing; Fang, Jun

    2017-02-01

    Emissions from equipment usage and transportation at the construction stage are classified as the direct emissions which include both greenhouse gas (GHG) and non-GHG emissions due to partial combustion of fuel. Unavailability of a reliable and complete inventory restricts an accurate emission evaluation on construction work. The study attempts to review emission factor standards readily available worldwide for estimating emissions from construction equipment. Emission factors published by United States Environmental Protection Agency (US EPA), Australian National Greenhouse Accounts (AUS NGA), Intergovernmental Panel on Climate Change (IPCC) and European Environmental Agency (EEA) are critically reviewed to identify their strengths and weaknesses. A selection process based on the availability and applicability is then developed to help identify the most suitable emission factor standards for estimating emissions from construction equipment in the Australian context. A case study indicates that a fuel based emission factor is more suitable for GHG emission estimation and a time based emission factor is more appropriate for estimation of non-GHG emissions. However, the selection of emission factor standards also depends on factors like the place of analysis (country of origin), data availability and the scope of analysis. Therefore, suitable modifications and assumptions should be incorporated in order to represent these factors. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. The effect of 3 torque delivery systems on gold screw preload at the gold cylinder-abutment screw joint.

    PubMed

    Tan, Keson B; Nicholls, Jack I

    2002-01-01

    This study measured the gold screw preload at the gold cylinder-abutment screw joint interface obtained by 3 torque delivery systems. Using a precalibrated, strain-gauged standard abutment as the load cell, 3 torque delivery systems tested were shown to have significant differences in gold screw preload when a gold cylinder was attached. Mean preloads measured were 291.2 N for hand torque drivers set at 10 Ncm, 340.3 N for electronic torque controllers at low setting/10 Ncm, 384.4 N for electronic torque controllers at high setting/10 Ncm; and 140.8 N for hand-tightening with a prosthetic slot screwdriver. Significant differences in screw preload were also found between operators using a hand torque driver. Hand-tightening delivered insufficient preload and cannot be recommended for final gold screw tightening. Different electronic torque controller units set at 10 Ncm induced mean gold screw preloads that ranged from 264.1 N to as high as 501.2 N. Electronic torque controllers should be regularly recalibrated to ensure optimal output.

  13. Shipboard Electronic Equipments.

    ERIC Educational Resources Information Center

    Naval Personnel Program Support Activity, Washington, DC.

    Fundamentals of major electronic equipments on board ships are presented in this text prepared for naval officers in general. Basic radio principles are discussed in connection with various types of transmitters, receivers, antennas, couplers, transfer panels, remote-control units, frequency standard equipments, teletypewriters, and facsimile…

  14. 49 CFR 19.34 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false Equipment. 19.34 Section 19.34 Transportation... Requirements Property Standards § 19.34 Equipment. (a) Title to equipment acquired by a recipient with Federal... use equipment acquired with Federal funds to provide services to non-Federal outside organizations for...

  15. 40 CFR 170.240 - Personal protective equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Personal protective equipment. 170.240... WORKER PROTECTION STANDARD Standard for Pesticide Handlers § 170.240 Personal protective equipment. (a... protective equipment specified on the labeling for use of the product. (b) Definition. (1) Personal...

  16. 40 CFR 440.140 - Applicability; description of the gold placer mine subcategory.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Applicability; description of the gold... AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS ORE MINING AND DRESSING POINT SOURCE CATEGORY Gold Placer Mine Subcategory § 440.140 Applicability; description of the gold placer mine subcategory. (a) The...

  17. 45 CFR 74.34 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Equipment. 74.34 Section 74.34 Public Welfare... COMMERCIAL ORGANIZATIONS Post-Award Requirements Property Standards § 74.34 Equipment. (a) Title to equipment... section. (b)(1) The recipient shall not use equipment acquired with HHS funds to provide services to non...

  18. Disinfection protocols for necropsy equipment in rabies laboratories: Safety of personnel and diagnostic outcome.

    PubMed

    Aiello, Roberta; Zecchin, Barbara; Tiozzo Caenazzo, Silvia; Cattoli, Giovanni; De Benedictis, Paola

    2016-08-01

    In the last decades, molecular techniques have gradually been adopted for the rapid confirmation of results obtained through gold standard methods. However, international organisations discourage their use in routine laboratory investigations for rabies post-mortem diagnosis, as they may lead to false positive results due to cross-contamination. Cleaning and disinfection are essential to prevent cross-contamination of samples in the laboratory environment. The present study evaluated the efficacy of selected disinfectants on rabies-contaminated necropsy equipment under organic challenge using a carrier-based test. The occurrence of detectable Rabies virus (RABV) antigen, viable virus and RNA was assessed through the gold standard Fluorescent Antibody Test, the Rabies Tissue Culture Infection Test and molecular techniques, respectively. None of the tested disinfectants proved to be effective under label conditions. Off label disinfection protocols were found effective for oxidizing agents and phenolic, only. Biguanide and quaternary ammonium compound were both ineffective under all tested conditions. Overall, discordant results were obtained when different diagnostic tests were compared, which means that in the presence of organic contamination common disinfectants may not be effective enough on viable RABV or RNA. Our results indicate that an effective disinfection protocol should be carefully validated to guarantee staff safety and reliability of results. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  19. Bottom-up formation of robust gold carbide

    PubMed Central

    Westenfelder, Benedikt; Biskupek, Johannes; Meyer, Jannik C.; Kurasch, Simon; Lin, Xiaohang; Scholz, Ferdinand; Gross, Axel; Kaiser, Ute

    2015-01-01

    A new phenomenon of structural reorganization is discovered and characterized for a gold-carbon system by in-situ atomic-resolution imaging at temperatures up to 1300 K. Here, a graphene sheet serves in three ways, as a quasi transparent substrate for aberration-corrected high-resolution transmission electron microscopy, as an in-situ heater, and as carbon supplier. The sheet has been decorated with gold nanoislands beforehand. During electron irradiation at 80 kV and at elevated temperatures, the accumulation of gold atoms has been observed on defective graphene sites or edges as well as at the facets of gold nanocrystals. Both resulted in clustering, forming unusual crystalline structures. Their lattice parameters and surface termination differ significantly from standard gold nanocrystals. The experimental data, supported by electron energy loss spectroscopy and density-functional theory calculations, suggests that isolated gold and carbon atoms form – under conditions of heat and electron irradiation – a novel type of compound crystal, Au-C in zincblende structure. The novel material is metastable, but surprisingly robust, even under annealing condition. PMID:25772348

  20. Testing Pneumonia Vaccines in the Elderly: Determining a Case Definition for Pneumococcal Pneumonia in the Absence of a Gold Standard.

    PubMed

    Jokinen, Jukka; Snellman, Marja; Palmu, Arto A; Saukkoriipi, Annika; Verlant, Vincent; Pascal, Thierry; Devaster, Jeanne-Marie; Hausdorff, William P; Kilpi, Terhi M

    2018-06-01

    Clinical assessments of vaccines to prevent pneumococcal community-acquired pneumonia (CAP) require sensitive and specific case definitions, but there is no gold standard diagnostic test. To develop a new case definition suitable for vaccine efficacy studies, we applied latent class analysis (LCA) to the results from 7 diagnostic tests for pneumococcal etiology on clinical specimens from 323 elderly persons with radiologically confirmed pneumonia enrolled in the Finnish Community-Acquired Pneumonia Epidemiology study during 2005-2007. Compared with the conventional use of LCA, which is mainly to determine sensitivities and specificities of different tests, we instead used LCA as an appropriate instrument to predict the probability of pneumococcal etiology for each CAP case based on individual test profiles, and we used the predictions to minimize the sample size that would be needed for a vaccine efficacy trial. When compared with the conventional laboratory criteria of encapsulated pneumococci in culture, in blood culture or high-quality sputum culture, or urine antigen positivity, our optimized case definition for pneumococcal CAP resulted in a trial sample size that was almost 20,000 subjects smaller. We believe that the novel application of LCA detailed here to determine a case definition for pneumococcal CAP could also be similarly applied to other diseases without a gold standard.

  1. Imaging of the optic disk in caring for patients with glaucoma: ophthalmoscopy and photography remain the gold standard.

    PubMed

    Spaeth, George L; Reddy, Swathi C

    2014-01-01

    Optic disk imaging is integral to the diagnosis and treatment of patients with glaucoma. We discuss the various forms of imaging the optic nerve, including ophthalmoscopy, photography, and newer imaging modalities, including optical coherence tomography (OCT), confocal scanning laser ophthalmoscopy (HRT), and scanning laser polarimetry (GDx), specifically highlighting their benefits and disadvantages. We argue that ophthalmoscopy and photography remain the gold standard of imaging due to portability, ease of interpretation, and the presence of a large database of images for comparison. Copyright © 2014 Elsevier Inc. All rights reserved.

  2. Cycloplegic refraction is the gold standard for epidemiological studies.

    PubMed

    Morgan, Ian G; Iribarren, Rafael; Fotouhi, Akbar; Grzybowski, Andrzej

    2015-09-01

    Many studies on children have shown that lack of cycloplegia is associated with slight overestimation of myopia and marked errors in estimates of the prevalence of emmetropia and hyperopia. Non-cycloplegic refraction is particularly problematic for studies of associations with risk factors. The consensus around the importance of cycloplegia in children left undefined at what age, if any, cycloplegia became unnecessary. It was often implicitly assumed that cycloplegia is not necessary beyond childhood or early adulthood, and thus, the protocol for the classical studies of refraction in older adults did not include cycloplegia. Now that population studies of refractive error are beginning to fill the gap between schoolchildren and older adults, whether cycloplegia is required for measuring refractive error in this age range, needs to be defined. Data from the Tehran Eye Study show that, without cycloplegia, there are errors in the estimation of myopia, emmetropia and hyperopia in the age range 20-50, just as in children. Similar results have been reported in an analysis of data from the Beaver Dam Offspring Eye Study. If the only important outcome measure of a particular study is the prevalence of myopia, then cycloplegia may not be crucial in some cases. But, without cycloplegia, measurements of other refractive categories as well as spherical equivalent are unreliable. In summary, the current evidence suggests that cycloplegic refraction should be considered as the gold standard for epidemiological studies of refraction, not only in children, but in adults up to the age of 50. © 2015 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  3. Mspire-Simulator: LC-MS shotgun proteomic simulator for creating realistic gold standard data.

    PubMed

    Noyce, Andrew B; Smith, Rob; Dalgleish, James; Taylor, Ryan M; Erb, K C; Okuda, Nozomu; Prince, John T

    2013-12-06

    The most important step in any quantitative proteomic pipeline is feature detection (aka peak picking). However, generating quality hand-annotated data sets to validate the algorithms, especially for lower abundance peaks, is nearly impossible. An alternative for creating gold standard data is to simulate it with features closely mimicking real data. We present Mspire-Simulator, a free, open-source shotgun proteomic simulator that goes beyond previous simulation attempts by generating LC-MS features with realistic m/z and intensity variance along with other noise components. It also includes machine-learned models for retention time and peak intensity prediction and a genetic algorithm to custom fit model parameters for experimental data sets. We show that these methods are applicable to data from three different mass spectrometers, including two fundamentally different types, and show visually and analytically that simulated peaks are nearly indistinguishable from actual data. Researchers can use simulated data to rigorously test quantitation software, and proteomic researchers may benefit from overlaying simulated data on actual data sets.

  4. 40 CFR 160.61 - Equipment design.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Equipment design. 160.61 Section 160.61 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS GOOD LABORATORY PRACTICE STANDARDS Equipment § 160.61 Equipment design. Equipment used in the generation...

  5. Reformation of Regulatory Technical Standards for Nuclear Power Generation Equipments in Japan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mikio Kurihara; Masahiro Aoki; Yu Maruyama

    2006-07-01

    Comprehensive reformation of the regulatory system has been introduced in Japan in order to apply recent technical progress in a timely manner. 'The Technical Standards for Nuclear Power Generation Equipments', known as the Ordinance No.622) of the Ministry of International Trade and Industry, which is used for detailed design, construction and operating stage of Nuclear Power Plants, was being modified to performance specifications with the consensus codes and standards being used as prescriptive specifications, in order to facilitate prompt review of the Ordinance with response to technological innovation. The activities on modification were performed by the Nuclear and Industrial Safetymore » Agency (NISA), the regulatory body in Japan, with support of the Japan Nuclear Energy Safety Organization (JNES), a technical support organization. The revised Ordinance No.62 was issued on July 1, 2005 and is enforced from January 1 2006. During the period from the issuance to the enforcement, JNES carried out to prepare enforceable regulatory guide which complies with each provisions of the Ordinance No.62, and also made technical assessment to endorse the applicability of consensus codes and standards, in response to NISA's request. Some consensus codes and standards were re-assessed since they were already used in regulatory review of the construction plan submitted by licensee. Other consensus codes and standards were newly assessed for endorsement. In case that proper consensus code or standards were not prepared, details of regulatory requirements were described in the regulatory guide as immediate measures. At the same time, appropriate standards developing bodies were requested to prepare those consensus code or standards. Supplementary note which provides background information on the modification, applicable examples etc. was prepared for convenience to the users of the Ordinance No. 62. This paper shows the activities on modification and the results, following

  6. A survey of current and anticipated use of standard and specialist equipment by UK optometrists.

    PubMed

    Dabasia, Priya L; Edgar, David F; Garway-Heath, David F; Lawrenson, John G

    2014-09-01

    To investigate current and anticipated use of equipment and information technology (IT) in community optometric practice in the UK, and to elicit optometrists' views on adoption of specialist equipment and IT. An anonymous online questionnaire was developed, covering use of standard and specialist diagnostic equipment, and IT. The survey was distributed to a random sample of 1300 UK College of Optometrists members. Four hundred and thirty-two responses were received (response rate = 35%). Enhanced (locally commissioned) or additional/separately contracted services were provided by 73% of respondents. Services included glaucoma repeat measures (30% of respondents), glaucoma referral refinement (22%), fast-track referral for wet age-related macular degeneration (48%), and direct cataract referral (40%). Most respondents (88%) reported using non-contact/pneumo tonometry for intra-ocular pressure measurement, with 81% using Goldmann or Perkins tonometry. The most widely used item of specialist equipment was the fundus camera (74% of respondents). Optical Coherence Tomography (OCT) was used by 15% of respondents, up from 2% in 2007. Notably, 43% of those anticipating purchasing specialist equipment in the next 12 months planned to buy an OCT. 'Paperless' records were used by 39% of respondents, and almost 80% of practices used an electronic patient record/practice management system. Variations in responses between parts of the UK reflect differences in the provision of the General Ophthalmic Services contract or community enhanced services. There was general agreement that specialised equipment enhances clinical care, permits increased involvement in enhanced services, promotes the practice and can be used as a defence in clinico-legal cases, but initial costs and ongoing maintenance can be a financial burden. Respondents generally agreed that IT facilitates administrative flow and secure exchange of health information, and promotes a state-of-the-art practice image

  7. 40 CFR 792.61 - Equipment design.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 31 2010-07-01 2010-07-01 true Equipment design. 792.61 Section 792.61 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) GOOD LABORATORY PRACTICE STANDARDS Equipment § 792.61 Equipment design. Equipment used in the...

  8. Exposure of Small-Scale Gold Miners in Prestea to Mercury, Ghana, 2012

    PubMed Central

    Mensah, Ebenezer Kofi; Afari, Edwin; Wurapa, Frederick; Sackey, Samuel; Quainoo, Albert; Kenu, Ernest; Nyarko, Kofi Mensah

    2016-01-01

    Introduction Small-scale gold miners in Ghana have been using mercury to amalgamate gold for many years. Mercury is toxic even at low concentration. We assessed occupational exposure of small-scale gold miners to mercury in Prestea, a gold mining town in Ghana. Methods We conducted a cross-sectional study in which we collected morning urine samples from 343 small-scale gold miners and tested for elemental mercury. Data on small-scale gold miner's socio-demographics, adverse health effects and occupational factors for mercury exposure were obtained and analyzed using SPSS Version 16 to determine frequency and percentage. Bivariate analysis was used to determine occupational factors associated with mercury exposure at 95% confidence level. Results The mean age of the small-scale gold miners was 29.5 ±9.6 years, and 323(94.20%) were males. One hundred and sixty (46.65%) of the small-scale gold miners had urine mercury above the recommended exposure limit (<5.0ug/L). Complaints of numbness were significantly associated with mercury exposure among those who have previously worked at other small-scale gold mines (χ2=4.96, p=0.03). The use of personal protective equipment among the small-scale gold miners was low. Retorts, which are globally recommended for burning amalgam, were not found at mining sites. Conclusion A large proportion of small-scale gold miners in Prestea were having mercury exposure in excess of occupational exposure limits, and are at risk of experiencing adverse health related complications. Ghana Environmental Protection Agency should organize training for the miners. PMID:28210374

  9. 14 CFR 25.1431 - Electronic equipment.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Electronic equipment. 25.1431 Section 25... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Miscellaneous Equipment § 25.1431 Electronic equipment. (a) In showing compliance with § 25.1309 (a) and (b) with respect to radio and electronic...

  10. 14 CFR 25.1431 - Electronic equipment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Electronic equipment. 25.1431 Section 25... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Miscellaneous Equipment § 25.1431 Electronic equipment. (a) In showing compliance with § 25.1309 (a) and (b) with respect to radio and electronic...

  11. 14 CFR 25.1431 - Electronic equipment.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Electronic equipment. 25.1431 Section 25... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Miscellaneous Equipment § 25.1431 Electronic equipment. (a) In showing compliance with § 25.1309 (a) and (b) with respect to radio and electronic...

  12. 14 CFR 25.1431 - Electronic equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Electronic equipment. 25.1431 Section 25... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Miscellaneous Equipment § 25.1431 Electronic equipment. (a) In showing compliance with § 25.1309 (a) and (b) with respect to radio and electronic...

  13. 40 CFR 792.61 - Equipment design.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 32 2011-07-01 2011-07-01 false Equipment design. 792.61 Section 792... (CONTINUED) GOOD LABORATORY PRACTICE STANDARDS Equipment § 792.61 Equipment design. Equipment used in the... of appropriate design and adequate capacity to function according to the protocol and shall be...

  14. 40 CFR 160.61 - Equipment design.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Equipment design. 160.61 Section 160... LABORATORY PRACTICE STANDARDS Equipment § 160.61 Equipment design. Equipment used in the generation... appropriate design and adequate capacity to function according to the protocol and shall be suitably located...

  15. Paper-based tuberculosis diagnostic devices with colorimetric gold nanoparticles

    NASA Astrophysics Data System (ADS)

    Tsai, Tsung-Ting; Shen, Shu-Wei; Cheng, Chao-Min; Chen, Chien-Fu

    2013-08-01

    A colorimetric sensing strategy employing gold nanoparticles and a paper assay platform has been developed for tuberculosis diagnosis. Unmodified gold nanoparticles and single-stranded detection oligonucleotides are used to achieve rapid diagnosis without complicated and time-consuming thiolated or other surface-modified probe preparation processes. To eliminate the use of sophisticated equipment for data analysis, the color variance for multiple detection results was simultaneously collected and concentrated on cellulose paper with the data readout transmitted for cloud computing via a smartphone. The results show that the 2.6 nM tuberculosis mycobacterium target sequences extracted from patients can easily be detected, and the turnaround time after the human DNA is extracted from clinical samples was approximately 1 h.

  16. 40 CFR 63.424 - Standards: Equipment leaks.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... are acceptable. Each piece of equipment shall be inspected during the loading of a gasoline cargo tank... implement an instrument leak monitoring program that has been demonstrated to the Administrator as at least... practicable; (3) Cover all open gasoline containers with a gasketed seal when not in use; (4) Minimize...

  17. 40 CFR 63.424 - Standards: Equipment leaks.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... are acceptable. Each piece of equipment shall be inspected during the loading of a gasoline cargo tank... implement an instrument leak monitoring program that has been demonstrated to the Administrator as at least... practicable; (3) Cover all open gasoline containers with a gasketed seal when not in use; (4) Minimize...

  18. 40 CFR 63.424 - Standards: Equipment leaks.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... are acceptable. Each piece of equipment shall be inspected during the loading of a gasoline cargo tank... implement an instrument leak monitoring program that has been demonstrated to the Administrator as at least... practicable; (3) Cover all open gasoline containers with a gasketed seal when not in use; (4) Minimize...

  19. 40 CFR 63.424 - Standards: Equipment leaks.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... are acceptable. Each piece of equipment shall be inspected during the loading of a gasoline cargo tank... implement an instrument leak monitoring program that has been demonstrated to the Administrator as at least... practicable; (3) Cover all open gasoline containers with a gasketed seal when not in use; (4) Minimize...

  20. 40 CFR 60.5401 - What are the exceptions to the equipment leak standards for affected facilities at onshore...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... equipment leak standards for affected facilities at onshore natural gas processing plants? 60.5401 Section... for affected facilities at onshore natural gas processing plants? (a) You may comply with the... is detected. (4)(i) Any pressure relief device that is located in a nonfractionating plant that is...

  1. 40 CFR 60.5401 - What are the exceptions to the equipment leak standards for affected facilities at onshore...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... equipment leak standards for affected facilities at onshore natural gas processing plants? 60.5401 Section... for affected facilities at onshore natural gas processing plants? (a) You may comply with the... is detected. (4)(i) Any pressure relief device that is located in a nonfractionating plant that is...

  2. The Study and Application of Hydrometallurgical Gold Leaching in the Analysis of Refractory Precious Metals

    NASA Astrophysics Data System (ADS)

    Yang, M.; Geng, X.; Wang, Y. L.; Li, D. X.

    2017-05-01

    Three orthogonal tests are separately designed for each hydrometallurgical gold leaching process to finding the optimum reaction conditions of melting gold and palladium in each process. Under the optimum condition, the determination amount of gold and palladium in aqua regia—hydrofluoric acid, Sodium thiosulfate, and potassium iodide reaches 2.87g/kg and 8.34 g/kg, 2.39g/kg and 8.12 g/kg, 2.51g/kg and 7.84g/kg. From the result, the content of gold and palladium using the leaching process of combining Aqua regia, hydrofluoric acid and hydrogen peroxide is relatively higher than the other processes. In addition, the experiment procedure of aqua regia digestion operates easily, using less equipment, and its period is short.

  3. 34 CFR 74.34 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... following standards: (1) For equipment with a current per unit fair market value of $5000 or more, the... the cost of the original project or program to the current fair market value of the equipment. (2) If... the current fair market value of the equipment, plus any reasonable shipping or interim storage costs...

  4. 2 CFR 215.34 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... disposal and sales price or the method used to determine current fair market value where a recipient... accordance with the following standards. For equipment with a current per unit fair market value of $5000 or... fair market value of the equipment. If the recipient has no need for the equipment, the recipient shall...

  5. 38 CFR 49.34 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... disposal and sales price or the method used to determine current fair market value where a recipient... accordance with the following standards. For equipment with a current per unit fair market value of $5000 or... fair market value of the equipment. If the recipient has no need for the equipment, the recipient shall...

  6. Annotated chemical patent corpus: a gold standard for text mining.

    PubMed

    Akhondi, Saber A; Klenner, Alexander G; Tyrchan, Christian; Manchala, Anil K; Boppana, Kiran; Lowe, Daniel; Zimmermann, Marc; Jagarlapudi, Sarma A R P; Sayle, Roger; Kors, Jan A; Muresan, Sorel

    2014-01-01

    Exploring the chemical and biological space covered by patent applications is crucial in early-stage medicinal chemistry activities. Patent analysis can provide understanding of compound prior art, novelty checking, validation of biological assays, and identification of new starting points for chemical exploration. Extracting chemical and biological entities from patents through manual extraction by expert curators can take substantial amount of time and resources. Text mining methods can help to ease this process. To validate the performance of such methods, a manually annotated patent corpus is essential. In this study we have produced a large gold standard chemical patent corpus. We developed annotation guidelines and selected 200 full patents from the World Intellectual Property Organization, United States Patent and Trademark Office, and European Patent Office. The patents were pre-annotated automatically and made available to four independent annotator groups each consisting of two to ten annotators. The annotators marked chemicals in different subclasses, diseases, targets, and modes of action. Spelling mistakes and spurious line break due to optical character recognition errors were also annotated. A subset of 47 patents was annotated by at least three annotator groups, from which harmonized annotations and inter-annotator agreement scores were derived. One group annotated the full set. The patent corpus includes 400,125 annotations for the full set and 36,537 annotations for the harmonized set. All patents and annotated entities are publicly available at www.biosemantics.org.

  7. Annotated Chemical Patent Corpus: A Gold Standard for Text Mining

    PubMed Central

    Akhondi, Saber A.; Klenner, Alexander G.; Tyrchan, Christian; Manchala, Anil K.; Boppana, Kiran; Lowe, Daniel; Zimmermann, Marc; Jagarlapudi, Sarma A. R. P.; Sayle, Roger; Kors, Jan A.; Muresan, Sorel

    2014-01-01

    Exploring the chemical and biological space covered by patent applications is crucial in early-stage medicinal chemistry activities. Patent analysis can provide understanding of compound prior art, novelty checking, validation of biological assays, and identification of new starting points for chemical exploration. Extracting chemical and biological entities from patents through manual extraction by expert curators can take substantial amount of time and resources. Text mining methods can help to ease this process. To validate the performance of such methods, a manually annotated patent corpus is essential. In this study we have produced a large gold standard chemical patent corpus. We developed annotation guidelines and selected 200 full patents from the World Intellectual Property Organization, United States Patent and Trademark Office, and European Patent Office. The patents were pre-annotated automatically and made available to four independent annotator groups each consisting of two to ten annotators. The annotators marked chemicals in different subclasses, diseases, targets, and modes of action. Spelling mistakes and spurious line break due to optical character recognition errors were also annotated. A subset of 47 patents was annotated by at least three annotator groups, from which harmonized annotations and inter-annotator agreement scores were derived. One group annotated the full set. The patent corpus includes 400,125 annotations for the full set and 36,537 annotations for the harmonized set. All patents and annotated entities are publicly available at www.biosemantics.org. PMID:25268232

  8. 40 CFR 63.1255 - Standards: Equipment leaks.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... requirements of this section. (9) Equipment that is in organic HAP service, but is in such service less than... required in paragraph (g)(9) of this section. (10) When each leak is detected by visual, audible, or... paragraphs (c)(5) through (9) of this section. (ii) Leak definition. The instrument reading, as determined by...

  9. Can an iPod Touch be used to assess whole-body vibration associated with mining equipment?

    PubMed

    Wolfgang, Rebecca; Di Corleto, Luke; Burgess-Limerick, Robin

    2014-11-01

    The cost and complexity of commercially available whole-body vibration measurement devices is a barrier to the systematic collection of the information required to manage this hazard. The potential for a consumer electronic device to be used to estimate whole-body vibration was assessed by collecting 58 simultaneous pairs of acceleration measurements in three dimensions from a fifth-generation iPod Touch and gold standard whole-body vibration measurement devices, while a range of heavy mining equipment was operated at three surface coal mines. The results suggest that accelerometer data gathered from a consumer electronic device are able to be used to measure whole-body vibration amplitude with 95% confidence of ±0.06 m s(-2) root mean square for the vertical direction (1.96 × standard deviation of the constant error). © The Author 2014. Published by Oxford University Press on behalf of the British Occupational Hygiene Society.

  10. 43 CFR 12.934 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... disposal and sales price or the method used to determine current fair market value where a recipient... accordance with the following standards. For equipment with a current per unit fair market value of $5,000 or... fair market value of the equipment. If the recipient has no need for the equipment, the recipient shall...

  11. 32 CFR 32.34 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... current fair market value where a recipient compensates the DoD Component that made the award for its... following standards. (1) For equipment with a current per unit fair market value of $5,000 or more, the... current fair market value of the equipment. (2) If the recipient has no need for the equipment, the...

  12. Reconsidering the H&E stain as the gold standard in assessing the depth of burn wounds.

    PubMed

    Rosenberg, Arlene S

    2017-12-01

    While histological examination is considered by most as the gold standard for burn depth assessment, it has no practical use in the clinical setting. It has, however, been used in the research setting, as a mean for evaluating emerging techniques of depth measurement. Due to the limitations of the H&E stain, other stains have also been explored, such as lactate dehydrogenase (LDH), as presented in this issue, in "Improving the Histologic Characterization of Burn Depth." As the determination of burn depth is not a typical subject in dermatopathology, a summary of selected techniques and the possible role for the LDH stain in future research, is described herein. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  13. Synthesis of gold structures by gold-binding peptide governed by concentration of gold ion and peptide.

    PubMed

    Kim, Jungok; Kim, Dong-Hun; Lee, Sylvia J; Rheem, Youngwoo; Myung, Nosang V; Hur, Hor-Gil

    2016-08-01

    Although biological synthesis methods for the production of gold structures by microorganisms, plant extracts, proteins, and peptide have recently been introduced, there have been few reports pertaining to controlling their size and morphology. The gold ion and peptide concentrations affected on the size and uniformity of gold plates by a gold-binding peptide Midas-11. The higher concentration of gold ions produced a larger size of gold structures reached 125.5 μm, but an increased amount of Midas-11 produced a smaller size of gold platelets and increased the yield percentage of polygonal gold particles rather than platelets. The mechanisms governing factors controlling the production of gold structures were primarily related to nucleation and growth. These results indicate that the synthesis of gold architectures can be controlled by newly isolated and substituted peptides under different reaction conditions.

  14. 29 CFR 1915.158 - Lifesaving equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) OCCUPATIONAL SAFETY AND HEALTH STANDARDS FOR SHIPYARD EMPLOYMENT Personal Protective Equipment (PPE) § 1915.158 Lifesaving equipment. (a) Personal flotation devices. (1) PFDs (life preservers, life... Equipment Specifications. (2) Prior to each use, personal floatation devices shall be inspected for dry rot...

  15. 29 CFR 1915.158 - Lifesaving equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) OCCUPATIONAL SAFETY AND HEALTH STANDARDS FOR SHIPYARD EMPLOYMENT Personal Protective Equipment (PPE) § 1915.158 Lifesaving equipment. (a) Personal flotation devices. (1) PFDs (life preservers, life... Equipment Specifications. (2) Prior to each use, personal floatation devices shall be inspected for dry rot...

  16. 10 CFR 600.134 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the following standards. Equipment with a current per-unit fair market value of less than $5000 may be... with a current per unit fair market value of $5000 or more, the recipient may retain the equipment for... the cost of the original project or program to the current fair market value of the equipment. If the...

  17. Hull, Mechanical, and Electrical Equipment Standardization in the U.S. Navy Surface Force: A Case of Competing Objectives and Stakeholder Trade-Off Decisions

    DTIC Science & Technology

    2007-12-14

    successful Standardization Program for Hull, Mechanical, and Electrical (HM&E) equipment and components of ships in the surface force costs the United......standardization will significantly increases the likelihood of achieving transformation successes . Properly identifying and understanding the root cause of a

  18. Is mini-laparoscopic cholecystectomy any better than the gold standard?: A comparative study.

    PubMed

    Shaikh, Haris R; Abbas, Asad; Aleem, Salik; Lakhani, Miqdad R

    2017-01-01

    Mini-laparoscopic cholecystectomy (MLC) has widened the horizons of modern laparoscopic surgery. Standard four port laparoscopic cholecystectomy (SLC), which has long been established as the "Gold Standard" for gall bladder diseases, is under reconsideration following the advent of further minimally-invasive procedures including MLC. Our study aims to provide a comparison between MLC and SLC and assesses whether MLC has any added benefits. Patients with symptomatic gall bladder disease undergoing MLC or SLC during the 2.5-month period were included in the study. Thirty-two patients underwent MLC while SLC was performed on 40 patients by the same surgeon. Data was collected prospectively and analysed retrospectively using a predesigned questionnaire. In our study, both the groups had similar age, body mass index (BMI) and gender distribution. No cases of MLC required insertion of additional ports. The mean operative time for MLC was 38.2 min (33-61 min), which is longer than SLC; but it was not statistically significant. There was no significant difference in mean operative blood loss, postoperative pain, analgesia requirement and mobilization. Patients who underwent MLC were able to return to normal activity earlier than patients undergoing SLC (P < 0.01). Our experience suggests that MLC can safely be used as an alternative to SLC. Compared to SLC, it has the added benefit of an early return to work along with excellent cosmetic results. Further large scale trials are required to prove any additional benefit of MLC.

  19. Space processing applications payload equipment study. Volume 2E: Commercial equipment utility

    NASA Technical Reports Server (NTRS)

    Smith, A. G. (Editor)

    1974-01-01

    Examination of commercial equipment technologies revealed that the functional performance requirements of space processing equipment could generally be met by state-of-the-art design practices. Thus, an apparatus could be evolved from a standard item or derived by custom design using present technologies. About 15 percent of the equipment needed has no analogous commercial base of derivation and requires special development. This equipment is involved primarily with contactless heating and position control. The derivation of payloads using commercial equipment sources provides a broad and potentially cost-effective base upon which to draw. The derivation of payload equipment from commercial technologies poses other issues beyond that of the identifiable functional performance, but preliminary results on testing of selected equipment testing appear quite favorable. During this phase of the SPA study, several aspects of commercial equipment utility were assessed and considered. These included safety, packaging and structural, power conditioning (electrical/electronic), thermal and materials of construction.

  20. cStress: Towards a Gold Standard for Continuous Stress Assessment in the Mobile Environment

    PubMed Central

    Hovsepian, Karen; al’Absi, Mustafa; Ertin, Emre; Kamarck, Thomas; Nakajima, Motohiro; Kumar, Santosh

    2015-01-01

    Recent advances in mobile health have produced several new models for inferring stress from wearable sensors. But, the lack of a gold standard is a major hurdle in making clinical use of continuous stress measurements derived from wearable sensors. In this paper, we present a stress model (called cStress) that has been carefully developed with attention to every step of computational modeling including data collection, screening, cleaning, filtering, feature computation, normalization, and model training. More importantly, cStress was trained using data collected from a rigorous lab study with 21 participants and validated on two independently collected data sets — in a lab study on 26 participants and in a week-long field study with 20 participants. In testing, the model obtains a recall of 89% and a false positive rate of 5% on lab data. On field data, the model is able to predict each instantaneous self-report with an accuracy of 72%. PMID:26543926

  1. Leishmania Infection: Laboratory Diagnosing in the Absence of a “Gold Standard”

    PubMed Central

    Rodríguez-Cortés, Alhelí; Ojeda, Ana; Francino, Olga; López-Fuertes, Laura; Timón, Marcos; Alberola, Jordi

    2010-01-01

    There is no gold standard for diagnosing leishmaniases. Our aim was to assess the operative validity of tests used in detecting Leishmania infection using samples from experimental infections, a reliable equivalent to the classic definition of gold standard. Without statistical differences, the highest sensitivity was achieved by protein A (ProtA), immunoglobulin (Ig)G2, indirect fluorescenece antibody test (IFAT), lymphocyte proliferation assay, quantitative real-time polymerase chain reaction of bone marrow (qPCR-BM), qPCR-Blood, and IgG; and the highest specificity by IgG1, IgM, IgA, qPCR-Blood, IgG, IgG2, and qPCR-BM. Maximum positive predictive value was obtained simultaneously by IgG2, qPCR-Blood, and IgG; and maximum negative predictive value by qPCR-BM. Best positive and negative likelihood ratios were obtained by IgG2. The test having the greatest, statistically significant, area under the receiver operating characteristics curve was IgG2 enzyme-linked immunosorbent assay (ELISA). Thus, according to the gold standard used, IFAT and qPCR are far from fulfilling the requirements to be considered gold standards, and the test showing the highest potential to detect Leishmania infection is Leishmania-specific ELISA IgG2. PMID:20134001

  2. Design of a medical and laboratory equipment management program for the new standards certification achievement in Mexico.

    PubMed

    Franco-Clark, D; Pimentel-Aguilar, A B; Rodriguez-Vera, R

    2010-01-01

    Certification for healthcare institutions in Mexico is ruled by 2009 standards homologated with the Joint Commission International criteria. Nowadays, healthcare requires of medical equipment and devices, so it has become necessary to implement guidelines for its adequate management in order to reach the highest level of quality and safety at the lowest cost. The objective of this work was to develop a Medical and Laboratory Equipment Management Program, oriented to the improvement of quality, effectiveness and efficiency of the technological resources in order to meet the certification requirements. The result of this work allows to have an auto evaluation tool that focuses the efforts of the National Institute for Respiratory Diseases to the achievement of the new requirements established for the certification.

  3. Standardization of Hull, Mechanical, and Electrical Equipment (H,M&E) inventory

    DTIC Science & Technology

    1987-09-01

    Miami University, 1974 M.B.A., George Washington University, 1985 Submitted in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE...Motors, Pumps, and Controllers) within the Weapon System 84 Interview with Messrs. George Blackmore, and William Bunge, Equipment Specialist, SPCC, May 18... George Blackmore, and William Bunge, SPCC, May 18, 1987. 52 V. S identical equipment. The reduction in the equipment range increased the volume for

  4. 30 CFR 75.1914 - Maintenance of diesel-powered equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... written standard operating procedures for such testing and evaluation that specify the following: (1) The... MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Diesel-Powered Equipment § 75... the equipment is operated. (d) The intake air filter on diesel-powered equipment shall be replaced or...

  5. 30 CFR 75.1914 - Maintenance of diesel-powered equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... written standard operating procedures for such testing and evaluation that specify the following: (1) The... MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Diesel-Powered Equipment § 75... the equipment is operated. (d) The intake air filter on diesel-powered equipment shall be replaced or...

  6. 30 CFR 75.1914 - Maintenance of diesel-powered equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... written standard operating procedures for such testing and evaluation that specify the following: (1) The... MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Diesel-Powered Equipment § 75... the equipment is operated. (d) The intake air filter on diesel-powered equipment shall be replaced or...

  7. 30 CFR 75.1914 - Maintenance of diesel-powered equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... written standard operating procedures for such testing and evaluation that specify the following: (1) The... MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Diesel-Powered Equipment § 75... the equipment is operated. (d) The intake air filter on diesel-powered equipment shall be replaced or...

  8. 30 CFR 75.1914 - Maintenance of diesel-powered equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... written standard operating procedures for such testing and evaluation that specify the following: (1) The... MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Diesel-Powered Equipment § 75... the equipment is operated. (d) The intake air filter on diesel-powered equipment shall be replaced or...

  9. 14 CFR 29.1431 - Electronic equipment.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Electronic equipment. 29.1431 Section 29... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment Miscellaneous Equipment § 29.1431 Electronic... operation of any other radio or electronic unit, or system of units, required by this chapter. ...

  10. 14 CFR 29.1431 - Electronic equipment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Electronic equipment. 29.1431 Section 29... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment Miscellaneous Equipment § 29.1431 Electronic... operation of any other radio or electronic unit, or system of units, required by this chapter. ...

  11. 14 CFR 29.1431 - Electronic equipment.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Electronic equipment. 29.1431 Section 29... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment Miscellaneous Equipment § 29.1431 Electronic... operation of any other radio or electronic unit, or system of units, required by this chapter. ...

  12. 14 CFR 29.1431 - Electronic equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Electronic equipment. 29.1431 Section 29... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment Miscellaneous Equipment § 29.1431 Electronic... operation of any other radio or electronic unit, or system of units, required by this chapter. ...

  13. Clinical, aetiological, anatomical and pathological classification (CEAP): gold standard and limits.

    PubMed

    Rabe, E; Pannier, F

    2012-03-01

    The first CEAP (clinical, aetiological, anatomical and pathological elements) consensus document was published after a consensus conference of the American Venous Forum, held at the sixth annual meeting of the AVF in February 1994 in Maui, Hawaii. In the following years the CEAP classification was published in many international journals and books which has led to widespread international use of the CEAP classification since 1995. The aim of this paper is to review the benefits and limits of CEAP from the available literature. In an actual Medline analysis with the keywords 'CEAP' and 'venous insufficiency', 266 publications using the CEAP classification in venous diseases are available. The CEAP classification was accepted in the venous community and used in scientific publications, but in most of the cases only the clinical classification was used. Limitations of the first version including a lack of clear definition of clinical signs led to a revised version. The CEAP classification is the gold standard of classification of chronic venous disorders today. Nevertheless for proper use some facts have to be taken into account: the CEAP classification is not a severity classification, C2 summarizes all kinds of varicose veins, in C3 it may be difficult to separate venous and other reasons for oedema, and corona phlebectatica is not included in the classification. Further revisions of the CEAP classification may help to overcome the still-existing deficits.

  14. 30 CFR 75.520 - Electric equipment; switches.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Electric equipment; switches. 75.520 Section 75... HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.520 Electric equipment; switches. [Statutory Provision] All electric equipment shall be provided with switches or other...

  15. 30 CFR 75.520 - Electric equipment; switches.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Electric equipment; switches. 75.520 Section 75... HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.520 Electric equipment; switches. [Statutory Provision] All electric equipment shall be provided with switches or other...

  16. 30 CFR 75.520 - Electric equipment; switches.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Electric equipment; switches. 75.520 Section 75... HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.520 Electric equipment; switches. [Statutory Provision] All electric equipment shall be provided with switches or other...

  17. 30 CFR 75.520 - Electric equipment; switches.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Electric equipment; switches. 75.520 Section 75... HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.520 Electric equipment; switches. [Statutory Provision] All electric equipment shall be provided with switches or other...

  18. 30 CFR 75.520 - Electric equipment; switches.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Electric equipment; switches. 75.520 Section 75... HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.520 Electric equipment; switches. [Statutory Provision] All electric equipment shall be provided with switches or other...

  19. Plastic deformation in nanoscale gold single crystals and open-celled nanoporous gold

    NASA Astrophysics Data System (ADS)

    Lee, Dongyun; Wei, Xiaoding; Zhao, Manhong; Chen, Xi; Jun, Seong C.; Hone, James; Kysar, Jeffrey W.

    2007-01-01

    The results of two sets of experiments to measure the elastic-plastic behaviour of gold at the nanometre length scale are reported. One set of experiments was on free-standing nanoscale single crystals of gold, and the other was on free-standing nanoscale specimens of open-celled nanoporous gold. Both types of specimens were fabricated from commercially available leaf which was either pure Au or a Au/Ag alloy following by dealloying of the Ag. Mechanical testing specimens of a 'dog-bone' shape were fabricated from the leaf using standard lithographic procedures after the leaf had been glued onto a silicon wafer. The thickness of the gauge portion of the specimens was about 100 nm, the width between 250 nm and 300 nm and the length 7 µm. The specimens were mechanically loaded with a nanoindenter (MTS) at the approximate midpoint of the gauge length. The resulting force-displacement curve of the single crystal gold was serrated and it was evident that slip localization occurred on individual slip systems; however, the early stages of the plastic deformation occurred in a non-localized manner. The results of detailed finite element analyses of the specimen suggest that the critical resolved shear stress of the gold single crystal was as high as 135 MPa which would lead to a maximum uniaxial stress of about 500 MPa after several per cent strain. The behaviour of the nanoporous gold was substantially different. It exhibited an apparent elastic behaviour until the point where it failed in an apparently brittle manner, although it is assumed that plastic deformation occurred in the ligaments prior to failure. The average elastic stiffness of three specimens was measured to be Enp = 8.8 GPa and the stress at ultimate failure averaged 190 MPa for the three specimens tested. Scaling arguments suggest that the stress in the individual ligaments could approach the theoretical shear strength. Presented at the IUTAM Symposium on Plasticity at the Micron Scale, Technical

  20. 14 CFR 25.1353 - Electrical equipment and installations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Electrical equipment and installations. 25... TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Electrical Systems and Equipment § 25.1353 Electrical equipment and installations. (a) Electrical equipment and controls must be...

  1. 14 CFR 25.1353 - Electrical equipment and installations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Electrical equipment and installations. 25... TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Electrical Systems and Equipment § 25.1353 Electrical equipment and installations. (a) Electrical equipment and controls must be...

  2. 14 CFR 25.1353 - Electrical equipment and installations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Electrical equipment and installations. 25... TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Electrical Systems and Equipment § 25.1353 Electrical equipment and installations. (a) Electrical equipment and controls must be...

  3. 14 CFR 29.1353 - Electrical equipment and installations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Electrical equipment and installations. 29... TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment Electrical Systems and Equipment § 29.1353 Electrical equipment and installations. (a) Electrical equipment, controls, and wiring...

  4. 14 CFR 29.1353 - Electrical equipment and installations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Electrical equipment and installations. 29... TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment Electrical Systems and Equipment § 29.1353 Electrical equipment and installations. (a) Electrical equipment, controls, and wiring...

  5. 14 CFR 25.1353 - Electrical equipment and installations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Electrical equipment and installations. 25... TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Electrical Systems and Equipment § 25.1353 Electrical equipment and installations. (a) Electrical equipment and controls must be...

  6. 14 CFR 29.1353 - Electrical equipment and installations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Electrical equipment and installations. 29... TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment Electrical Systems and Equipment § 29.1353 Electrical equipment and installations. (a) Electrical equipment, controls, and wiring...

  7. 29 CFR 95.34 - Equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...-PROFIT ORGANIZATIONS, AND WITH COMMERCIAL ORGANIZATIONS, FOREIGN GOVERNMENTS, ORGANIZATIONS UNDER THE JURISDICTION OF FOREIGN GOVERNMENTS, AND INTERNATIONAL ORGANIZATIONS Post-Award Requirements Property Standards... the Federal Government retains an interest in the equipment. (c) The recipient shall use the equipment...

  8. 29 CFR 95.34 - Equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...-PROFIT ORGANIZATIONS, AND WITH COMMERCIAL ORGANIZATIONS, FOREIGN GOVERNMENTS, ORGANIZATIONS UNDER THE JURISDICTION OF FOREIGN GOVERNMENTS, AND INTERNATIONAL ORGANIZATIONS Post-Award Requirements Property Standards... the Federal Government retains an interest in the equipment. (c) The recipient shall use the equipment...

  9. 29 CFR 95.34 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...-PROFIT ORGANIZATIONS, AND WITH COMMERCIAL ORGANIZATIONS, FOREIGN GOVERNMENTS, ORGANIZATIONS UNDER THE JURISDICTION OF FOREIGN GOVERNMENTS, AND INTERNATIONAL ORGANIZATIONS Post-Award Requirements Property Standards... the Federal Government retains an interest in the equipment. (c) The recipient shall use the equipment...

  10. Gold Rush!

    ERIC Educational Resources Information Center

    Brahier, Daniel J.

    1997-01-01

    Describes a mathematical investigation of gold--how it is weighed, stored, used, and valued. For grades 3-4, children estimate the value of treasure chests filled with gold coins and explore the size and weight of gold bars. Children in grades 5-6 explore how gold is mined and used, and how the value of gold changes over time. (PVD)

  11. 14 CFR 29.1307 - Miscellaneous equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment General § 29.1307 Miscellaneous equipment. The... arrangement for electrical circuits other than ignition. (c) Hand fire extinguishers. (d) A windshield wiper...

  12. Accuracy of computed tomographic angiography for stenosis quantification using quantitative coronary angiography or intravascular ultrasound as the gold standard.

    PubMed

    Joshi, Subodh B; Okabe, Teruo; Roswell, Robert O; Weissman, Gaby; Lopez, Cristian F; Lindsay, Joseph; Pichard, Augusto D; Weissman, Neil J; Waksman, Ron; Weigold, Wm Guy

    2009-10-15

    Computed tomographic angiography (CTA) is considered to have limited accuracy for quantifying exact percent diameter stenosis in coronary arteries. However, most studies evaluating CTA use quantitative coronary angiography (QCA) as the gold standard, a technique with its own limitations. We sought to determine whether CTA measurements of stenosis severity correlate better with intravascular ultrasound (IVUS) than with QCA. Luminal dimensions of 67 de novo coronary lesions were measured by CTA, IVUS, and QCA. IVUS was performed when lesion severity by angiography was equivocal. Mean percent diameter stenosis by QCA was 51 +/- 9.8% and mean IVUS minimal luminal area was 3.8 +/- 1.8 mm(2). There was a moderate correlation between CTA minimal luminal area and IVUS minimal luminal area (r(2) = 0.41, p <0.001), but no relation between CTA and QCA measurements of minimal luminal diameter (r(2) = 0.01, p = 0.57) or diameter stenosis (r(2) = 0.02, p = 0.31). There was also no relation between IVUS minimal luminal area and QCA diameter stenosis (r(2) = 0.01, p = 0.50). When lesions with moderate or severe calcification were excluded, the correlation between CTA minimal luminal area and IVUS minimal luminal area was good (r(2) = 0.68, p <0.001). In conclusion, in this cohort of patients with intermediate-grade lesions on cardiac catheterization, absolute measurements of stenosis severity on CTA correlated with IVUS but not with QCA. Our findings suggest that limitations of quantitative coronary angiography as a gold standard need to be considered in studies evaluating the accuracy of coronary CTA.

  13. Gold

    USGS Publications Warehouse

    Kirkemo, Harold; Newman, William L.; Ashley, Roger P.

    1998-01-01

    Through the ages, men and women have cherished gold, and many have had a compelling desire to amass great quantities of it -- so compelling a desire, in fact, that the frantic need to seek and hoard gold has been aptly named "gold fever." Gold was among the first metals to be mined because it commonly occurs in its native form -- that is, not combined with other elements -- because it is beautiful and imperishable, and because exquisite objects can be made from it.

  14. Patterning of oxide-hardened gold black by photolithography and metal lift-off

    Treesearch

    Deep Panjwani; Mehmet Yesiltas; Janardan Nath; D.E. Maukonen; Imen Rezadad; Evan M. Smith; R.E. Peale; Carol Hirschmugl; Julia Sedlmair; Ralf Wehlitz; Miriam Unger; Glenn Boreman

    2014-01-01

    A method to pattern infrared-absorbing gold black by conventional photolithography and lift-off is described. A photo-resist pattern is developed on a substrate by standard photolithography. Gold black is deposited over the whole by thermal evaporation in an inert gas at

  15. 29 CFR 95.34 - Equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... ORGANIZATIONS, AND WITH COMMERCIAL ORGANIZATIONS, FOREIGN GOVERNMENTS, ORGANIZATIONS UNDER THE JURISDICTION OF FOREIGN GOVERNMENTS, AND INTERNATIONAL ORGANIZATIONS Post-Award Requirements Property Standards § 95.34... the Federal Government retains an interest in the equipment. (c) The recipient shall use the equipment...

  16. Gold in minerals and the composition of native gold

    USGS Publications Warehouse

    Jones, Robert Sprague; Fleischer, Michael

    1969-01-01

    Gold occurs in nature mainly as the metal and as various alloys. It forms complete series of solid solutions with silver, copper, nickel, palladium, and platinum. In association with the platinum metals, gold occurs as free gold as well as in solid solution. The native elements contain the most gold, followed by the sulfide minerals. Several gold tellurides are known, but no gold selenides have been reported, and only one sulfide, the telluride-sulfide mineral nagyagite, is known. The nonmetallic minerals carry the least gold, and the light-colored minerals generally contain less gold than the dark minerals. Some conclusions in the literature are conflicting in regard to the relation of fineness of native gold to its position laterally and vertically within a lode, the nature of the country rocks, and the location and size of nuggets in a streambed, as well as to the variation of fineness within an individual nugget.

  17. 14 CFR 25.1307 - Miscellaneous equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment General § 25.1307 Miscellaneous equipment. The... electrical energy. (c) Electrical protective devices, as prescribed in this part. (d) Two systems for two-way...

  18. A cost and utility analysis of NIM/CAMAC standards and equipment for shuttle payload data acquisition and control systems. Volume 3: Tasks 3 and 4

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The modifications for the Nuclear Instrumentation Modular (NIM) and Computer Automated Measurement Control (CAMAC) equipment, designed for ground based laboratory use, that would be required to permit its use in the Spacelab environments were determined. The cost of these modifications were estimated and the most cost effective approach to implementing them were identified. A shared equipment implementation in which the various Spacelab users draw their required complement of standard NIM and CAMAC equipment for a given flight from a common equipment pool was considered. The alternative approach studied was a dedicated equipment implementation in which each of the users is responsible for procuring either their own NIM/CAMAC equipment or its custom built equivalent.

  19. The challenge of determining handedness in electron tomography and the use of DNA origami gold nanoparticle helices as molecular standards

    PubMed Central

    Briegel, Ariane; Pilhofer, Martin; Mastronarde, David N.; Jensen, Grant J.

    2013-01-01

    The apparent handedness of an EM-tomography reconstruction depends on a number of conventions and can be confused in many ways. As the number of different hardware and software combinations being used for electron tomography continue to climb, and the reconstructions being produced reach higher and higher resolutions, the need to verify the hand of the results has increased. Here we enumerate various steps in a typical tomography experiment that affect handedness and show that DNA origami gold nanoparticle helices can be used as convenient and fail-safe handedness standards. PMID:23639902

  20. Energy-efficiency labels and standards: A guidebook for appliances, equipment and lighting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McMahon, James E.; Wiel, Stephen

    2001-02-16

    Energy-performance improvements in consumer products are an essential element in any government's portfolio of energy-efficiency and climate change mitigation programs. Governments need to develop balanced programs, both voluntary and regulatory, that remove cost-ineffective, energy-wasting products from the marketplace and stimulate the development of cost-effective, energy-efficient technology. Energy-efficiency labels and standards for appliances, equipment, and lighting products deserve to be among the first policy tools considered by a country's energy policy makers. The U.S. Agency for International Development (USAID) and the United Nations Foundation (UNF) recognize the need to support policy makers in their efforts to implement energy-efficiency standards and labelingmore » programs and have developed this guidebook, together with the Collaborative Labeling and Appliance Standards Program (CLASP), as a primary reference. This guidebook was prepared over the course of the past year with significant contribution from the authors and reviewers mentioned previously. Their diligent participation has made this the international guidance tool it was intended to be. The lead authors would also like to thank the following individuals for their support in the development, production, and distribution of the guidebook: Marcy Beck, Elisa Derby, Diana Dhunke, Ted Gartner, and Julie Osborn of Lawrence Berkeley National Laboratory as well as Anthony Ma of Bevilacqua-Knight, Inc. This guidebook is designed as a manual for government officials and others around the world responsible for developing, implementing, enforcing, monitoring, and maintaining labeling and standards-setting programs. It discusses the pros and cons of adopting energy-efficiency labels and standards and describes the data, facilities, and institutional and human resources needed for these programs. It provides guidance on the design, development, implementation, maintenance, and evaluation of the

  1. Derivatized gold clusters and antibody-gold cluster conjugates

    DOEpatents

    Hainfeld, James F.; Furuya, Frederic R.

    1994-11-01

    Antibody- or antibody fragment-gold cluster conjugates are shown wherein the conjugate size can be as small as 5.0 nm. Methods and reagents are disclosed in which antibodies, Fab' or F(ab').sub.2 fragments thereof are covalently bound to a stable cluster of gold atoms. The gold clusters may contain 6, 8, 9, 11, 13, 55 or 67 gold atoms in their inner core. The clusters may also contain radioactive gold. The antibody-cluster conjugates are useful in electron microscopy applications as well as in clinical applications that include imaging, diagnosis and therapy.

  2. Terminalia chebula mediated green and rapid synthesis of gold nanoparticles

    NASA Astrophysics Data System (ADS)

    Mohan Kumar, Kesarla; Mandal, Badal Kumar; Sinha, Madhulika; Krishnakumar, Varadhan

    2012-02-01

    Biologically inspired experimental process in synthesising nanoparticles is of great interest in present scenario. Biosynthesis of nanoparticles is considered to be one of the best green techniques in synthesising metal nanoparticles. Here, an in situ green biogenic synthesis of gold nanoparticles using aqueous extracts of Terminalia chebula as reducing and stabilizing agent is reported. Gold nanoparticles were confirmed by surface plasmon resonance in the range of 535 nm using UV-visible spectrometry. TEM analysis revealed that the morphology of the particles thus formed contains anisotropic gold nanoparticles with size ranging from 6 to 60 nm. Hydrolysable tannins present in the extract of T. chebula are responsible for reductions and stabilization of gold nanoparticles. Antimicrobial activity of gold nanoparticles showed better activity towards gram positive S. aureus compared to gram negative E. coli using standard well diffusion method.

  3. Systematic comparison of variant calling pipelines using gold standard personal exome variants

    PubMed Central

    Hwang, Sohyun; Kim, Eiru; Lee, Insuk; Marcotte, Edward M.

    2015-01-01

    The success of clinical genomics using next generation sequencing (NGS) requires the accurate and consistent identification of personal genome variants. Assorted variant calling methods have been developed, which show low concordance between their calls. Hence, a systematic comparison of the variant callers could give important guidance to NGS-based clinical genomics. Recently, a set of high-confident variant calls for one individual (NA12878) has been published by the Genome in a Bottle (GIAB) consortium, enabling performance benchmarking of different variant calling pipelines. Based on the gold standard reference variant calls from GIAB, we compared the performance of thirteen variant calling pipelines, testing combinations of three read aligners—BWA-MEM, Bowtie2, and Novoalign—and four variant callers—Genome Analysis Tool Kit HaplotypeCaller (GATK-HC), Samtools mpileup, Freebayes and Ion Proton Variant Caller (TVC), for twelve data sets for the NA12878 genome sequenced by different platforms including Illumina2000, Illumina2500, and Ion Proton, with various exome capture systems and exome coverage. We observed different biases toward specific types of SNP genotyping errors by the different variant callers. The results of our study provide useful guidelines for reliable variant identification from deep sequencing of personal genomes. PMID:26639839

  4. Evaluating gold standard corpora against gene/protein tagging solutions and lexical resources

    PubMed Central

    2013-01-01

    Motivation The identification of protein and gene names (PGNs) from the scientific literature requires semantic resources: Terminological and lexical resources deliver the term candidates into PGN tagging solutions and the gold standard corpora (GSC) train them to identify term parameters and contextual features. Ideally all three resources, i.e. corpora, lexica and taggers, cover the same domain knowledge, and thus support identification of the same types of PGNs and cover all of them. Unfortunately, none of the three serves as a predominant standard and for this reason it is worth exploring, how these three resources comply with each other. We systematically compare different PGN taggers against publicly available corpora and analyze the impact of the included lexical resource in their performance. In particular, we determine the performance gains through false positive filtering, which contributes to the disambiguation of identified PGNs. Results In general, machine learning approaches (ML-Tag) for PGN tagging show higher F1-measure performance against the BioCreative-II and Jnlpba GSCs (exact matching), whereas the lexicon based approaches (LexTag) in combination with disambiguation methods show better results on FsuPrge and PennBio. The ML-Tag solutions balance precision and recall, whereas the LexTag solutions have different precision and recall profiles at the same F1-measure across all corpora. Higher recall is achieved with larger lexical resources, which also introduce more noise (false positive results). The ML-Tag solutions certainly perform best, if the test corpus is from the same GSC as the training corpus. As expected, the false negative errors characterize the test corpora and – on the other hand – the profiles of the false positive mistakes characterize the tagging solutions. Lex-Tag solutions that are based on a large terminological resource in combination with false positive filtering produce better results, which, in addition, provide

  5. 41 CFR 105-72.404 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... disposal and sales price or the method used to determine current fair market value where a recipient... accordance with the following standards. For equipment with a current per unit fair market value of $5000 or... fair market value of the equipment. If the recipient has no need for the equipment, the recipient shall...

  6. Preparation of TNT, RDX and Ammonium Nitrate Standards on Gold-on-Silicon Surfaces by Thermal Inkjet Technology

    NASA Astrophysics Data System (ADS)

    Wrable-Rose, Madeline; Primera-Pedrozo, Oliva M.; Pacheco-Londoño, Leonardo C.; Hernandez-Rivera, Samuel P.

    2010-12-01

    This research examines the surface contamination properties, trace sample preparation methodologies, detection systems response and generation of explosive contamination standards for trace detection systems. Homogeneous and reproducible sample preparation is relevant for trace detection of chemical threats, such as warfare agents, highly energetic materials (HEM) and toxic industrial chemicals. The objective of this research was to develop a technology capable of producing samples and standards of HEM with controlled size and distribution on a substrate to generate specimens that would reproduce real contamination conditions. The research activities included (1) a study of the properties of particles generated by two deposition techniques: sample smearing deposition and inkjet deposition, on gold-coated silicon, glass and stainless steel substrates; (2) characterization of composition, distribution and adhesion characteristics of deposits; (3) evaluation of accuracy and reproducibility for depositing neat highly energetic materials such as TNT, RDX and ammonium nitrate; (4) a study of HEM-surface interactions using FTIR-RAIRS; and (5) establishment of protocols for validation of surface concentration using destructive methods such as HPLC.

  7. Direct Animal Calorimetry, the Underused Gold Standard for Quantifying the Fire of Life*

    PubMed Central

    Kaiyala, Karl J.; Ramsay, Douglas S.

    2012-01-01

    Direct animal calorimetry, the gold standard method for quantifying animal heat production (HP), has been largely supplanted by respirometric indirect calorimetry owing to the relative ease and ready commercial availability of the latter technique. Direct calorimetry, however, can accurately quantify HP and thus metabolic rate (MR) in both metabolically normal and abnormal states, whereas respirometric indirect calorimetry relies on important assumptions that apparently have never been tested in animals with genetic or pharmacologically-induced alterations that dysregulate metabolic fuel partitioning and storage so as to promote obesity and/or diabetes. Contemporary obesity and diabetes research relies heavily on metabolically abnormal animals. Recent data implicating individual and group variation in the gut microbiome in obesity and diabetes raise important questions about transforming aerobic gas exchange into HP because 99% of gut bacteria are anaerobic and they outnumber eukaryotic cells in the body by ~10-fold. Recent credible work in non-standard laboratory animals documents substantial errors in respirometry-based estimates of HP. Accordingly, it seems obvious that new research employing simultaneous direct and indirect calorimetry (total calorimetry) will be essential to validate respirometric MR phenotyping in existing and future pharmacological and genetic models of obesity and diabetes. We also detail the use of total calorimetry with simultaneous core temperature assessment as a model for studying homeostatic control in a variety of experimental situations, including acute and chronic drug administration. Finally, we offer some tips on performing direct calorimetry, both singly and in combination with indirect calorimetry and core temperature assessment. PMID:20427023

  8. 40 CFR 440.140 - Applicability; description of the gold placer mine subcategory.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS ORE MINING AND DRESSING POINT SOURCE CATEGORY Gold... gold bearing ores from placer deposits; and (2) The beneficiation processes which use gravity... applicable to any mines or beneficiation processes which process less than 1500 cubic yards (cu yd) of ore...

  9. Derivatized gold clusters and antibody-gold cluster conjugates

    DOEpatents

    Hainfeld, J.F.; Furuya, F.R.

    1994-11-01

    Antibody- or antibody fragment-gold cluster conjugates are shown wherein the conjugate size can be as small as 5.0 nm. Methods and reagents are disclosed in which antibodies, Fab' or F(ab')[sub 2] fragments are covalently bound to a stable cluster of gold atoms. The gold clusters may contain 6, 8, 9, 11, 13, 55 or 67 gold atoms in their inner core. The clusters may also contain radioactive gold. The antibody-cluster conjugates are useful in electron microscopy applications as well as in clinical applications that include imaging, diagnosis and therapy. 7 figs.

  10. Using a web-based application to define the accuracy of diagnostic tests when the gold standard is imperfect.

    PubMed

    Lim, Cherry; Wannapinij, Prapass; White, Lisa; Day, Nicholas P J; Cooper, Ben S; Peacock, Sharon J; Limmathurotsakul, Direk

    2013-01-01

    Estimates of the sensitivity and specificity for new diagnostic tests based on evaluation against a known gold standard are imprecise when the accuracy of the gold standard is imperfect. Bayesian latent class models (LCMs) can be helpful under these circumstances, but the necessary analysis requires expertise in computational programming. Here, we describe open-access web-based applications that allow non-experts to apply Bayesian LCMs to their own data sets via a user-friendly interface. Applications for Bayesian LCMs were constructed on a web server using R and WinBUGS programs. The models provided (http://mice.tropmedres.ac) include two Bayesian LCMs: the two-tests in two-population model (Hui and Walter model) and the three-tests in one-population model (Walter and Irwig model). Both models are available with simplified and advanced interfaces. In the former, all settings for Bayesian statistics are fixed as defaults. Users input their data set into a table provided on the webpage. Disease prevalence and accuracy of diagnostic tests are then estimated using the Bayesian LCM, and provided on the web page within a few minutes. With the advanced interfaces, experienced researchers can modify all settings in the models as needed. These settings include correlation among diagnostic test results and prior distributions for all unknown parameters. The web pages provide worked examples with both models using the original data sets presented by Hui and Walter in 1980, and by Walter and Irwig in 1988. We also illustrate the utility of the advanced interface using the Walter and Irwig model on a data set from a recent melioidosis study. The results obtained from the web-based applications were comparable to those published previously. The newly developed web-based applications are open-access and provide an important new resource for researchers worldwide to evaluate new diagnostic tests.

  11. Biometry and intraocular lens power calculation results with a new optical biometry device: comparison with the gold standard.

    PubMed

    Kaswin, Godefroy; Rousseau, Antoine; Mgarrech, Mohamed; Barreau, Emmanuel; Labetoulle, Marc

    2014-04-01

    To evaluate the agreement in axial length (AL), keratometry (K), anterior chamber depth (ACD) measurements; intraocular lens (IOL) power calculations; and predictability using a new partial coherence interferometry (PCI) optical biometer (AL-Scan) and a reference (gold standard) PCI optical biometer (IOLMaster 500). Service d'Ophtalmologie, Hopital Bicêtre, APHP Université, Paris, France. Evaluation of a diagnostic device. One eye of consecutive patients scheduled for cataract surgery was measured. Biometry was performed with the new biometer and the reference biometer. Comparisons were performed for AL, average K at 2.4 mm, ACD, IOL power calculations with the Haigis and SRK/T formulas, and postoperative predictability of the devices. A P value less than 0.05 was statistically significant. The study enrolled 50 patients (mean age 72.6 years±4.2 SEM). There was a good correlation between biometers for AL, K, and ACD measurements (r=0.999, r=0.933, and r=0.701, respectively) and between IOL power calculation with the Haigis formula (r=0.972) and the SRK/T formula (r=0.981). The mean absolute error (MAE) in IOL power prediction was 0.42±0.08 diopter (D) with the new biometer and 0.44±0.08 D with the reference biometer. The MAE was 0.20 D with the Haigis formula and 0.19 with the SRK/T formula (P=.36). The new PCI biometer provided valid measurements compared with the current gold standard, indicating that the new device can be used for IOL power calculations for routine cataract surgery. No author has a financial or proprietary interest in any material or method mentioned. Copyright © 2014 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  12. Metal-assisted chemical etching using sputtered gold: a simple route to black silicon

    NASA Astrophysics Data System (ADS)

    Kurek, Agnieszka; Barry, Seán T.

    2011-08-01

    We report an accessible and simple method of producing 'black silicon' with aspect ratios as high as 8 using common laboratory equipment. Gold was sputtered to a thickness of 8 nm using a low-vacuum sputter coater. The structures were etched into silicon substrates using an aqueous H2O2/HF solution, and the gold was then removed using aqua regia. Ultrasonication was necessary to produce columnar structures, and an etch time of 24 min gave a velvety, non-reflective surface. The surface features after 24 min etching were uniformly microstructured over an area of square centimetres.

  13. 22 CFR 145.34 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Equipment. 145.34 Section 145.34 Foreign Relations DEPARTMENT OF STATE CIVIL RIGHTS GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Property Standards § 145.34 Equipment...

  14. Using operational equipment to read accident dosemeters.

    PubMed

    Devine, R T; Vigil, M M; Martinez, W A

    2004-01-01

    Analysis of accident dosemeters usually involves the use of laboratory-based counting equipment. Gamma spectrometers are used for indium, copper and gold, and alpha-beta detectors for sulphur. This equipment is usually not easily transported due to the shielding required and the weight and delicacy of the counters. For intercomparison studies that require reading the dosemeters on site, a transportable system is required unless the site operating the study can count samples for all the participants. In the case of an actual accident these systems would have a difficulty in counting a large number of accident dosemeters. In an accident, personnel are usually subdivided according to their level of exposure. Those exposed to higher doses are treated immediately. An alternate system should be made available to handle the dosemeters worn by those personnel are likely to receive lower doses. Improvements in portable operational equipment for gamma and beta monitoring allow their use as spectrometers. Such a system was used for the SILENE intercomparison conducted at IRSN Valduc on 12 June and 19, 2002, and the preliminary results compared well with the other participants.

  15. Not All That Glitters is Gold: Gold Imitations in History.

    PubMed

    Karpenko, Vladimír

    2007-07-01

    When gold became considered as a precious metal for decorative purposes and later for coinage, attempts at producing imitations soon began to appear. There were two motives behind this activity: to make a metal that could pass as gold, and to quite openly imitate this precious metal for people who could not afford true gold. Imitation gold was produced by metallurgists, and later also by alchemists. This paper is about gold imitations that did not contain any precious metal. Gold-like alloys of silver are thus excluded. An attempt is further undertaken to classify into separate groups the various gold imitations that have appeared in different cultures throughout time, with an emphasis on brass as a typical imitation of gold.

  16. Decision Making in the Management of Extracapsular Fractures of the Proximal Femur – is the Dynamic Hip Screw the Prevailing Gold Standard?

    PubMed Central

    Jacob, Joshua; Desai, Ankit; Trompeter, Alex

    2017-01-01

    Currently, approximately half of all hip fractures are extracapsular, with an incidence as high as 50 in 100,000 in some countries. The common classification systems fail to explain the logistics of fracture classification and whether they all behave in the same manner. The Muller AO classification system is a useful platform to delineate stable and unstable fractures. The Dynamic hip screw (DHS) however, has remained the ‘gold standard’ implant of choice for application in all extracapsular fractures. The DHS relies on the integrity and strength of the lateral femoral wall as well as the postero-medial fragment. An analysis of several studies indicates significant improvements in design and techniques to ensure a better outcome with intramedullary nails. This article reviews the historical trends that helped to evolve the DHS implant as well as discussing if the surgeon should remain content with this implant. We suggest that the gold standard surgical management of extracapsular fractures can, and should, evolve. PMID:29290858

  17. Management methodology for pressure equipment

    NASA Astrophysics Data System (ADS)

    Bletchly, P. J.

    Pressure equipment constitutes a significant investment in capital and a major proportion of potential high-risk plant in many operations and this is particularly so in an alumina refinery. In many jurisdictions pressure equipment is also subject to statutory regulation that imposes obligations on Owners of the equipment with respect to workplace safety. Most modern technical standards and industry codes of practice employ a risk-based approach to support better decision making with respect to pressure equipment. For a management system to be effective it must demonstrate that risk is being managed within acceptable limits.

  18. Non-standard equipment for construction of vertical shafts

    NASA Astrophysics Data System (ADS)

    Yagodkin, F. I.; Prokopov, A. Y.; Pleshko, M. S.; Pankratenko, A. N.

    2017-10-01

    The article deals with the modern problems of construction and reconstruction of vertical shafts of mines, which require innovative technical solutions in the mechanization of mining operations. The examples developed by the authors of the original equipment and technologies, are successfully implemented for the mining industry in Russia.

  19. Genomes OnLine Database (GOLD) v.6: data updates and feature enhancements

    PubMed Central

    Mukherjee, Supratim; Stamatis, Dimitri; Bertsch, Jon; Ovchinnikova, Galina; Verezemska, Olena; Isbandi, Michelle; Thomas, Alex D.; Ali, Rida; Sharma, Kaushal; Kyrpides, Nikos C.; Reddy, T. B. K.

    2017-01-01

    The Genomes Online Database (GOLD) (https://gold.jgi.doe.gov) is a manually curated data management system that catalogs sequencing projects with associated metadata from around the world. In the current version of GOLD (v.6), all projects are organized based on a four level classification system in the form of a Study, Organism (for isolates) or Biosample (for environmental samples), Sequencing Project and Analysis Project. Currently, GOLD provides information for 26 117 Studies, 239 100 Organisms, 15 887 Biosamples, 97 212 Sequencing Projects and 78 579 Analysis Projects. These are integrated with over 312 metadata fields from which 58 are controlled vocabularies with 2067 terms. The web interface facilitates submission of a diverse range of Sequencing Projects (such as isolate genome, single-cell genome, metagenome, metatranscriptome) and complex Analysis Projects (such as genome from metagenome, or combined assembly from multiple Sequencing Projects). GOLD provides a seamless interface with the Integrated Microbial Genomes (IMG) system and supports and promotes the Genomic Standards Consortium (GSC) Minimum Information standards. This paper describes the data updates and additional features added during the last two years. PMID:27794040

  20. Phage based green chemistry for gold ion reduction and gold retrieval.

    PubMed

    Setyawati, Magdiel I; Xie, Jianping; Leong, David T

    2014-01-22

    The gold mining industry has taken its toll on the environment, triggering the development of more environmentally benign processes to alleviate the waste load release. Here, we demonstrate the use of bacteriophages (phages) for biosorption and bioreduction of gold ions from aqueous solution, which potentially can be applied to remediate gold ions from gold mining waste effluent. Phage has shown a remarkably efficient sorption of gold ions with a maximum gold adsorption capacity of 571 mg gold/g dry weight phage. The product of this phage mediated process is gold nanocrystals with the size of 30-630 nm. Biosorption and bioreduction processes are mediated by the ionic and covalent interaction between gold ions and the reducing groups on the phage protein coat. The strategy offers a simple, ecofriendly and feasible option to recover of gold ions to form readily recoverable products of gold nanoparticles within 24 h.

  1. 31 CFR 100.4 - Gold coin and gold certificates in general.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false Gold coin and gold certificates in... MONETARY OFFICES, DEPARTMENT OF THE TREASURY EXCHANGE OF PAPER CURRENCY AND COIN In General § 100.4 Gold coin and gold certificates in general. Gold coins, and gold certificates of the type issued before...

  2. 31 CFR 100.4 - Gold coin and gold certificates in general.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance: Treasury 1 2013-07-01 2013-07-01 false Gold coin and gold certificates in... MONETARY OFFICES, DEPARTMENT OF THE TREASURY EXCHANGE OF PAPER CURRENCY AND COIN In General § 100.4 Gold coin and gold certificates in general. Gold coins, and gold certificates of the type issued before...

  3. 31 CFR 100.4 - Gold coin and gold certificates in general.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false Gold coin and gold certificates in... MONETARY OFFICES, DEPARTMENT OF THE TREASURY EXCHANGE OF PAPER CURRENCY AND COIN In General § 100.4 Gold coin and gold certificates in general. Gold coins, and gold certificates of the type issued before...

  4. 31 CFR 100.4 - Gold coin and gold certificates in general.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 1 2014-07-01 2014-07-01 false Gold coin and gold certificates in... MONETARY OFFICES, DEPARTMENT OF THE TREASURY EXCHANGE OF PAPER CURRENCY AND COIN In General § 100.4 Gold coin and gold certificates in general. Gold coins, and gold certificates of the type issued before...

  5. 31 CFR 100.4 - Gold coin and gold certificates in general.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Gold coin and gold certificates in... EXCHANGE OF PAPER CURRENCY AND COIN In General § 100.4 Gold coin and gold certificates in general. Gold coins, and gold certificates of the type issued before January 30, 1934, are exchangeable, as provided...

  6. Optimization of gold ore Sumbawa separation using gravity method: Shaking table

    NASA Astrophysics Data System (ADS)

    Ferdana, Achmad Dhaefi; Petrus, Himawan Tri Bayu Murti; Bendiyasa, I. Made; Prijambada, Irfan Dwidya; Hamada, Fumio; Sachiko, Takahi

    2018-04-01

    Most of artisanal small gold mining in Indonesia has been using amalgamation method, which caused negative impact to the environment around ore processing area due to the usage of mercury. One of the more environmental-friendly method for gold processing is gravity method. Shaking table is one of separation equipment of gravity method used to increase concentrate based on difference of specific gravity. The optimum concentration result is influenced by several variables, such as rotational speed shaking, particle size and deck slope. In this research, the range of rotational speed shaking was between 100 rpm and 200 rpm, the particle size was between -100 + 200 mesh and -200 + 300 mesh and deck slope was between 3° and 7°. Gold concentration in concentrate was measured by EDX. The result shows that the optimum condition is obtained at a shaking speed of 200 rpm, with a slope of 7° and particle size of -100 + 200 mesh.

  7. 24 CFR 84.34 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Equipment. 84.34 Section 84.34 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development UNIFORM... NON-PROFIT ORGANIZATIONS Post-Award Requirements Property Standards § 84.34 Equipment. (a) Title to...

  8. Gold and gold working in Late Bronze Age Northern Greece.

    PubMed

    Vavelidis, M; Andreou, S

    2008-04-01

    Numerous objects of gold displaying an impressive variety of types and manufacturing techniques are known from the Late Bronze Age (LBA) contexts of Mycenaean Greece, but very little is known about the origin and processing of gold during the second millennium B.C: . Ancient literature and recent research indicate that northern Greece is probably the richest gold-bearing region in Greece, and yet, very little evidence exists regarding the exploitation of its deposits and the production as well as use of gold in the area during prehistory. The unusual find of a group of small stone crucibles at the prehistoric settlement of Thessaloniki Toumba, one with visible traces of gold melting, proves local production and offers a rare opportunity to examine the process of on-site gold working. Furthermore, the comparison of the chemical composition of prehistoric artefacts from two settlements with those of gold deposits in their immediate areas supports the local extraction of gold and opens up the prospect for some of the Mycenaean gold to have originated in northern Greece. The scarcity of gold items in northern Greek LBA contexts may not represent the actual amount of gold produced and consumed, but could be a result of the local social attitudes towards the circulation and deposition of artefacts from precious metals.

  9. Gold and gold working in Late Bronze Age Northern Greece

    NASA Astrophysics Data System (ADS)

    Vavelidis, M.; Andreou, S.

    2008-04-01

    Numerous objects of gold displaying an impressive variety of types and manufacturing techniques are known from the Late Bronze Age (LBA) contexts of Mycenaean Greece, but very little is known about the origin and processing of gold during the second millennium b.c. Ancient literature and recent research indicate that northern Greece is probably the richest gold-bearing region in Greece, and yet, very little evidence exists regarding the exploitation of its deposits and the production as well as use of gold in the area during prehistory. The unusual find of a group of small stone crucibles at the prehistoric settlement of Thessaloniki Toumba, one with visible traces of gold melting, proves local production and offers a rare opportunity to examine the process of on-site gold working. Furthermore, the comparison of the chemical composition of prehistoric artefacts from two settlements with those of gold deposits in their immediate areas supports the local extraction of gold and opens up the prospect for some of the Mycenaean gold to have originated in northern Greece. The scarcity of gold items in northern Greek LBA contexts may not represent the actual amount of gold produced and consumed, but could be a result of the local social attitudes towards the circulation and deposition of artefacts from precious metals.

  10. Changing organizational culture: using the CEO cancer gold standard policy initiatives to promote health and wellness at a school of public health.

    PubMed

    Towne, Samuel D; Anderson, Kelsey E; Smith, Matthew Lee; Dahlke, Deborah Vollmer; Kellstedt, Debra; Purcell, Ninfa Pena; Ory, Marcia G

    2015-09-03

    Worksite wellness initiatives for health promotion and health education have demonstrated effectiveness in improving employee health and wellness. We examined the effects of a multifaceted health promotion campaign on organizational capacity to meet requirements to become CEO Cancer Gold Standard Accredited. We conducted an online survey to assess perceived organizational values and support for the five CEO Cancer Gold Standard Pillars for cancer prevention: tobacco cessation; physical activity; nutrition; cancer screening and early detection; and accessing information on cancer clinical trials. Baseline and follow-up surveys were sent 6-months apart to faculty, staff, and students at a school of public health to test the impact of a multifaceted health promotion campaign on perceived organizational change. Descriptive analyses were used to characterize percent improvement. Multivariate logistic regression analyses were used to control for participants' university status. The current organizational culture highly supported tobacco cessation at both time points. Significant improvements (p < .05) from baseline to follow-up were observed for questions measuring organizational values for 'prevention, screening, and early detection of cancer' and 'accessing cancer treatment and clinical trials'. Health promotion and education efforts using multiple approaches were effective to improve perceived organizational values and support for cancer prevention and early detection, and increase access to information about cancer clinical trials. Future studies are needed to examine broader impacts of implementing worksite health promotion initiatives.

  11. 36 CFR 292.44 - Use of motorized and mechanical equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... mechanical equipment. 292.44 Section 292.44 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF... motorized and mechanical equipment. The standards and guidelines of this section apply to the use of motorized and mechanical equipment in the HCNRA. These standards and guidelines shall not be construed to...

  12. 30 CFR 70.300 - Respiratory equipment; respirable dust.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Respiratory equipment; respirable dust. 70.300... SAFETY AND HEALTH MANDATORY HEALTH STANDARDS-UNDERGROUND COAL MINES Respiratory Equipment § 70.300 Respiratory equipment; respirable dust. Respiratory equipment approved by NIOSH under 42 CFR part 84 shall be...

  13. 30 CFR 70.300 - Respiratory equipment; respirable dust.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Respiratory equipment; respirable dust. 70.300... SAFETY AND HEALTH MANDATORY HEALTH STANDARDS-UNDERGROUND COAL MINES Respiratory Equipment § 70.300 Respiratory equipment; respirable dust. Respiratory equipment approved by NIOSH under 42 CFR part 84 shall be...

  14. 30 CFR 70.300 - Respiratory equipment; respirable dust.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Respiratory equipment; respirable dust. 70.300... SAFETY AND HEALTH MANDATORY HEALTH STANDARDS-UNDERGROUND COAL MINES Respiratory Equipment § 70.300 Respiratory equipment; respirable dust. Respiratory equipment approved by NIOSH under 42 CFR part 84 shall be...

  15. 30 CFR 70.300 - Respiratory equipment; respirable dust.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Respiratory equipment; respirable dust. 70.300... SAFETY AND HEALTH MANDATORY HEALTH STANDARDS-UNDERGROUND COAL MINES Respiratory Equipment § 70.300 Respiratory equipment; respirable dust. Respiratory equipment approved by NIOSH under 42 CFR part 84 shall be...

  16. 30 CFR 70.300 - Respiratory equipment; respirable dust.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Respiratory equipment; respirable dust. 70.300... SAFETY AND HEALTH MANDATORY HEALTH STANDARDS-UNDERGROUND COAL MINES Respiratory Equipment § 70.300 Respiratory equipment; respirable dust. Respiratory equipment approved by NIOSH under 42 CFR part 84 shall be...

  17. Artisanal and Small-Scale Gold Mining Without Mercury

    EPA Pesticide Factsheets

    Mercury-free techniques are safer for miners, their families and local communities. They can also help miners qualify for certification under fair-mined standards, potentially allowing them to market their gold at higher prices.

  18. 40 CFR 63.1363 - Standards for equipment leaks.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... mechanical seal system that includes a barrier fluid system and meets the requirements specified in... dual mechanical seal system is: (A) Operated with the barrier fluid at a pressure that is at all times... paragraph (a)(2) of this section. (5) Lines and equipment not containing process fluids are not subject to...

  19. 30 CFR 75.500 - Permissible electric equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Permissible electric equipment. 75.500 Section... AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.500 Permissible electric equipment. [Statutory Provision] On and after March 30, 1971: (a) All junction or...

  20. 30 CFR 75.500 - Permissible electric equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Permissible electric equipment. 75.500 Section... AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.500 Permissible electric equipment. [Statutory Provision] On and after March 30, 1971: (a) All junction or...

  1. 30 CFR 75.500 - Permissible electric equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Permissible electric equipment. 75.500 Section... AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.500 Permissible electric equipment. [Statutory Provision] On and after March 30, 1971: (a) All junction or...

  2. 30 CFR 75.500 - Permissible electric equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Permissible electric equipment. 75.500 Section... AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.500 Permissible electric equipment. [Statutory Provision] On and after March 30, 1971: (a) All junction or...

  3. 30 CFR 75.500 - Permissible electric equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Permissible electric equipment. 75.500 Section... AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.500 Permissible electric equipment. [Statutory Provision] On and after March 30, 1971: (a) All junction or...

  4. Anesthesia equipment malfunction: origins and clinical recognition.

    PubMed Central

    McIntyre, J. W.

    1979-01-01

    Equipment malfunction is a problem of particular importance during anesthesia and resuscitation. A review of published reports shows that the most common clinical events involve endotracheal tubes, the inspired oxygen concentration, the volume of inspired anesthetic vapours and gases, and pressures in the breathing or ventilation system. It is concluded that protection of a patient from equipment malfunction depends on: (a) appropriate application of standards set by a national standards association; (b) careful evaluation of equipment prior to purchase; (c) comprehension of equipment function by the user; (d) conscientious routine servicing of all systems concerned with anesthesia and resuscitation, and checking after service and before clinical use; (e) preanesthesia testing of equipment, including the use of an oxygen analyser in the breathing circuit; (f) early inclusion of equipment malfunction in the differential diagnosis of events during anesthesia; and (g) rapid action that cannot present a new hazard to the patient to correct the results of apparatus malfunction. PMID:436069

  5. Equipment of medical backpacks in mountain rescue.

    PubMed

    Elsensohn, Fidel; Soteras, Inigo; Resiten, Oliver; Ellerton, John; Brugger, Hermann; Paal, Peter

    2011-01-01

    We conducted a survey of equipment in medical backpacks for mountain rescuers and mountain emergency physicians. The aim was to investigate whether there are standards for medical equipment in mountain rescue organizations associated with the International Commission for Mountain Emergency Medicine (ICAR MEDCOM). A questionnaire was completed by 18 member organizations from 14 countries. Backpacks for first responders are well equipped to manage trauma, but deficiencies in equipment to treat medical emergencies were found. Paramedic and physicians' backpacks were well equipped to provide advanced life support and contained suitable drugs. We recommend that medical backpacks should be equipped in accordance with national laws, the medical emergencies in a given region, and take into account the climate, geography, medical training of rescuers, and funding of the organization. Automated external defibrillator provision should be improved. The effects of temperature on the drugs and equipment should be considered. Standards for training in the use and maintenance of medical tools should be enforced. First responders and physicians should only use familiar tools and drugs.

  6. 40 CFR 63.1363 - Standards for equipment leaks.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... that is in vacuum service is excluded from the requirements of this section. (9) Equipment that is in... requirements of this section if it is identified as required in paragraph (g)(9) of this section. (10) When..., 63.178, paragraph (f) of this section, and paragraphs (c)(5) through (9) of this section. (ii) Leak...

  7. 40 CFR 63.1363 - Standards for equipment leaks.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... that is in vacuum service is excluded from the requirements of this section. (9) Equipment that is in... requirements of this section if it is identified as required in paragraph (g)(9) of this section. (10) When..., 63.178, paragraph (f) of this section, and paragraphs (c)(5) through (9) of this section. (ii) Leak...

  8. 40 CFR 440.140 - Applicability; description of the gold placer mine subcategory.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS (CONTINUED) ORE MINING AND DRESSING POINT SOURCE... that produce gold or gold bearing ores from placer deposits; and (2) The beneficiation processes which... yards (cu yd) of ore per year, or to dredges which process less than 50,000 cu yd of ore per year, or to...

  9. 40 CFR 440.140 - Applicability; description of the gold placer mine subcategory.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS (CONTINUED) ORE MINING AND DRESSING POINT SOURCE... that produce gold or gold bearing ores from placer deposits; and (2) The beneficiation processes which... yards (cu yd) of ore per year, or to dredges which process less than 50,000 cu yd of ore per year, or to...

  10. 40 CFR 440.140 - Applicability; description of the gold placer mine subcategory.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS (CONTINUED) ORE MINING AND DRESSING POINT SOURCE... that produce gold or gold bearing ores from placer deposits; and (2) The beneficiation processes which... yards (cu yd) of ore per year, or to dredges which process less than 50,000 cu yd of ore per year, or to...

  11. 30 CFR 72.520 - Diesel equipment inventory.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Diesel equipment inventory. 72.520 Section 72... HEALTH HEALTH STANDARDS FOR COAL MINES Diesel Particulate Matter-Underground Areas of Underground Coal Mines § 72.520 Diesel equipment inventory. (a) The operator of each mine that utilizes diesel equipment...

  12. 30 CFR 72.520 - Diesel equipment inventory.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Diesel equipment inventory. 72.520 Section 72... HEALTH HEALTH STANDARDS FOR COAL MINES Diesel Particulate Matter-Underground Areas of Underground Coal Mines § 72.520 Diesel equipment inventory. (a) The operator of each mine that utilizes diesel equipment...

  13. 30 CFR 72.520 - Diesel equipment inventory.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Diesel equipment inventory. 72.520 Section 72... HEALTH HEALTH STANDARDS FOR COAL MINES Diesel Particulate Matter-Underground Areas of Underground Coal Mines § 72.520 Diesel equipment inventory. (a) The operator of each mine that utilizes diesel equipment...

  14. 30 CFR 72.520 - Diesel equipment inventory.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Diesel equipment inventory. 72.520 Section 72... HEALTH HEALTH STANDARDS FOR COAL MINES Diesel Particulate Matter-Underground Areas of Underground Coal Mines § 72.520 Diesel equipment inventory. (a) The operator of each mine that utilizes diesel equipment...

  15. 30 CFR 72.520 - Diesel equipment inventory.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Diesel equipment inventory. 72.520 Section 72... HEALTH HEALTH STANDARDS FOR COAL MINES Diesel Particulate Matter-Underground Areas of Underground Coal Mines § 72.520 Diesel equipment inventory. (a) The operator of each mine that utilizes diesel equipment...

  16. 47 CFR 27.51 - Equipment authorization.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Equipment authorization. 27.51 Section 27.51 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES Technical Standards § 27.51 Equipment authorization. (a) Each transmitter utilized for...

  17. 47 CFR 27.51 - Equipment authorization.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false Equipment authorization. 27.51 Section 27.51 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES Technical Standards § 27.51 Equipment authorization. (a) Each transmitter utilized for...

  18. 40 CFR 30.34 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the following standards. For equipment with a current per unit fair market value of $5000 or more, the... cost of the original project or program to the current fair market value of the equipment, plus any... data, including date of disposal and sales price or the method used to determine current fair market...

  19. The shape of Au8: gold leaf or gold nugget?

    NASA Astrophysics Data System (ADS)

    Serapian, Stefano A.; Bearpark, Michael J.; Bresme, Fernando

    2013-06-01

    The size at which nonplanar isomers of neutral, pristine gold nanoclusters become energetically favored over planar ones is still debated amongst theoreticians and experimentalists. Spectroscopy confirms planarity is preferred at sizes up to Au7, however, starting with Au8, the uncertainty remains for larger nanoclusters. Au8 computational studies have had different outcomes: the planar D4h ``cloverleaf'' isomer competes with the nonplanar Td, C2v and D2d ``nugget'' isomers for greatest energetic stability. We here examine the 2D vs. 3D preference in Au8 by presenting our own B2PLYP, MP2 and CCSD(T) calculations on these isomers: these methods afford a better treatment of long-range correlation, which is at the root of gold's characteristic aurophilicity. We then use findings from these high-accuracy computations to evaluate two less expensive DFT approaches, applicable to much larger nanoclusters: alongside the standard functional PBE, we consider M06-L (highly parametrized to incorporate long-range dispersive interactions). We find that increasing basis set size within the B2PLYP framework has a greater destabilizing effect on the nuggets than it has on the Au8 cloverleaf. Our CCSD(T) and B2PLYP predictions, replicated by DFT-PBE, all identify the cloverleaf as the most stable isomer; MP2 and DFT-M06-L show overestimation of aurophilicity, and favor, respectively, the nonplanar D2d and Td nuggets in its stead. We conclude that PBE, which more closely reproduces CCSD(T) findings, may be a better candidate density functional for the simulation of gold nanoclusters in this context.The size at which nonplanar isomers of neutral, pristine gold nanoclusters become energetically favored over planar ones is still debated amongst theoreticians and experimentalists. Spectroscopy confirms planarity is preferred at sizes up to Au7, however, starting with Au8, the uncertainty remains for larger nanoclusters. Au8 computational studies have had different outcomes: the planar D4

  20. Measuring Retention in HIV Care: The Elusive Gold Standard

    PubMed Central

    Mugavero, Michael J.; Westfall, Andrew O.; Zinski, Anne; Davila, Jessica; Drainoni, Mari-Lynn; Gardner, Lytt I.; Keruly, Jeanne C.; Malitz, Faye; Marks, Gary; Metsch, Lisa; Wilson, Tracey E.; Giordano, Thomas P.

    2012-01-01

    Background Measuring retention in HIV primary care is complex as care includes multiple visits scheduled at varying intervals over time. We evaluated six commonly used retention measures in predicting viral load (VL) suppression and the correlation among measures. Methods Clinic-wide patient-level data from six academic HIV clinics were used for 12-months preceding implementation of the CDC/HRSA Retention in Care intervention. Six retention measures were calculated for each patient based upon scheduled primary HIV provider visits: count and dichotomous missed visits, visit adherence, 6-month gap, 4-month visit constancy, and the HRSA HAB retention measure. Spearman correlation coefficients and separate unadjusted logistic regression models compared retention measures to one another and with 12-month VL suppression, respectively. The discriminatory capacity of each measure was assessed with the c-statistic. Results Among 10,053 patients, 8,235 (82%) had 12-month VL measures, with 6,304 (77%) achieving suppression (VL<400 c/mL). All six retention measures were significantly associated (P<0.0001) with VL suppression (OR;95%CI, c-statistic): missed visit count (0.73;0.71–0.75,0.67), missed visit dichotomous (3.2;2.8–3.6,0.62), visit adherence (3.9;3.5–4.3,0.69), gap (3.0;2.6–3.3,0.61), visit constancy (2.8;2.5–3.0,0.63), HRSA HAB (3.8;3.3–4.4,0.59). Measures incorporating “no show” visits were highly correlated (Spearman coefficient=0.83–0.85), as were measures based solely upon kept visits (Spearman coefficient=0.72–0.77). Correlation coefficients were lower across these two groups of measures (Range=0.16–0.57). Conclusions Six retention measures displayed a wide range of correlation with one another, yet each measure had significant association and modest discrimination for VL suppression. These data suggest there is no clear gold standard, and that selection of a retention measure may be tailored to context. PMID:23011397

  1. 29 CFR 1910.306 - Specific purpose equipment and installations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... and multicar installations. On single-car and multicar installations, equipment receiving electrical... ADMINISTRATION, DEPARTMENT OF LABOR OCCUPATIONAL SAFETY AND HEALTH STANDARDS Electrical Design Safety Standards for Electrical Systems § 1910.306 Specific purpose equipment and installations. (a) Electric signs and...

  2. 29 CFR 1910.306 - Specific purpose equipment and installations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... and multicar installations. On single-car and multicar installations, equipment receiving electrical... ADMINISTRATION, DEPARTMENT OF LABOR OCCUPATIONAL SAFETY AND HEALTH STANDARDS Electrical Design Safety Standards for Electrical Systems § 1910.306 Specific purpose equipment and installations. (a) Electric signs and...

  3. 29 CFR 1910.306 - Specific purpose equipment and installations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... and multicar installations. On single-car and multicar installations, equipment receiving electrical... ADMINISTRATION, DEPARTMENT OF LABOR OCCUPATIONAL SAFETY AND HEALTH STANDARDS Electrical Design Safety Standards for Electrical Systems § 1910.306 Specific purpose equipment and installations. (a) Electric signs and...

  4. 14 CFR 25.1309 - Equipment, systems, and installations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment General § 25.1309... electrical system and equipment design and installation, critical environmental conditions must be considered. For electrical generation, distribution, and utilization equipment required by or used in complying...

  5. Electrochemical Recovery of Gold from Waste Electric and Electronic Equipment Using Circulating Particulate Bed Reactor (CPBE)

    NASA Astrophysics Data System (ADS)

    Ravinder, T.; Ali, U. F. M.; Ridwan, F. M.; Ibrahim, N.; Azmi, N. H.

    2017-06-01

    The utilization of electrochemical process recovery involving low reactant concentrations of metal requires electrodes with high mass transport rates and specific surface areas. This is essential to increase cross-sectional current densities whilst optimizing the capital and operating costs. Experimental results demonstrated that Circulating Particulate Bed Reactor (CPBE) is suitable for the recovery of low concentrations of gold from aqueous chloride solution containing {{AuCl}}4- and {{AuCl}}2- of less than 0.5 mol m-3(< 102 g m-3). Elemental gold was successfully obtained on 0.5-1 mm gr particles in an electrochemical reactor incorporating a cation- permeable membrane and operated in bath recycle mode. Depletion to concentration < 5 × 10-3 mol m-3 (< 1 g m-3) appeared to be mass transport controlled at an applied potential of +0.20 V (SCE), specific electrical energy consumption (SEEC) of ca. 800-1300 kWh h (tonne Au)-1 for cell voltages (U) of 2.0-3.0 V, and fractional current efficiencies of ca. 0.95. However, atomic absorption and UV spectrophotometry established that as the ([{{AuCl}}4-+[{{AuCl}}2-]) concentration decayed, the [{{AuCl}}4-]:[{{AuCl}}2-] molar ratio changed. A multi-step mechanism for reduction of {{AuCl}}4- ions explained this behavior in terms of changing overpotentials for {{AuCl}}4- and {{AuCl}}2- reduction as total dissolved gold concentration decreased. In addition, SEM images confirmed that adherent and coherent Au deposits were achieved with CPBE for Au deposition under mass transport control at 0.20 V (SCE).

  6. Personal Protective Equipment for Pesticide Handlers

    EPA Pesticide Factsheets

    Personal protective equipment.use is subject to certain requirement under the Worker Protection Standard. Learn about these requirements, which include cleaning and maintenance, as well as standards for availability.

  7. 29 CFR 95.34 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... disposal and sales price or the method used to determine current fair market value where a recipient... following standards. For equipment with a current per unit fair market value of $5,000 or more, the... in the cost of the original project or program to the current fair market value of the equipment. If...

  8. Equipment Management Manual

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The NASA Equipment Management Manual (NHB 4200.1) is issued pursuant to Section 203(c)(1) of the National Aeronautics and Space Act of 1958, as amended (42 USC 2473), and sets forth policy, uniform performance standards, and procedural guidance to NASA personnel for the acquisition, management, and use of NASA-owned equipment. This revision is effective upon receipt. This is a controlled manual, issued in loose-leaf form, and revised through page changes. Additional copies for internal use may be obtained through normal distribution.

  9. Ghost Particle Velocimetry: Accurate 3D Flow Visualization Using Standard Lab Equipment

    NASA Astrophysics Data System (ADS)

    Buzzaccaro, Stefano; Secchi, Eleonora; Piazza, Roberto

    2013-07-01

    We describe and test a new approach to particle velocimetry, based on imaging and cross correlating the scattering speckle pattern generated on a near-field plane by flowing tracers with a size far below the diffraction limit, which allows reconstructing the velocity pattern in microfluidic channels without perturbing the flow. As a matter of fact, adding tracers is not even strictly required, provided that the sample displays sufficiently refractive-index fluctuations. For instance, phase separation in liquid mixtures in the presence of shear is suitable to be directly investigated by this “ghost particle velocimetry” technique, which just requires a microscope with standard lamp illumination equipped with a low-cost digital camera. As a further bonus, the peculiar spatial coherence properties of the illuminating source, which displays a finite longitudinal coherence length, allows for a 3D reconstruction of the profile with a resolution of few tenths of microns and makes the technique suitable to investigate turbid samples with negligible multiple scattering effects.

  10. Geostatistical Approach to Estimating the Gold Ore Characteristics and Gold Reserves: A Case Study Daksa Area, Quang Nam Province, Viet Nam

    NASA Astrophysics Data System (ADS)

    Luan Truong, Xuan; Luong Le, Van; Quang Truong, Xuan

    2015-04-01

    Daksa gold deposit is the biggest gold deposits in Vietnam. The Daksa geological structure complicated, distributed mainly metamorphosed sedimentary NuiVu formation (PR3-?1nv2). The sulfide gold ore bodies distributed in quartz schist, quartz - biotite related to faut and distribution wing anticline. The gold ore bodies form circuits, network circuits, circuits lenses; fill the cup surface layer of the developing northeast - southwest; is the less than or west longitude north - SE. The results show that, Au and accompanying elements (Ag, Pb and Zn) have correlated pretty closely. All of its consistent with the logarithmic distribution standard, in accordance with the law of distribution of content mineral rare. The structure functions have nugget effect and spherical models with show that Au and accompanying elements special variation are changes. Au contents shown local anisotropy, no clearly anisotropy (K=1,17) and weakly anisotropy (K=1,4). Intensity mineralization of the ore bodies are quite high with demand spherical conversion coefficient ranging from 0.49 to 0.75 and from 0.66 to 0.97 (for other body). With nugget effects, ore bodies shown that it is consistent with mineralization in the ore bodies study, ore erasable, micro vein, infilling fractures in quartz vein. All of variogram presents local anisotropy, indicated gold mineralization at study area has least two-mineralization stages, consistent with the analysis of mineralography samples. By the results of the structure function study, the authors present the system optimization for exploration deposit and used to evaluate gold reserves by Ordinary Kriging. High accuracy of Kriging estimation results are expressed in the minimum Kriging variance, by compare the results calculated by some other methods (such as distance inverse weighting method, ..) and specially compare to the results of a some blocks have been exploited. Key words: Geostat and gold deposits VN. Daksa and gold mineralization. Geostat

  11. LOCALIZATION OF GOLD IN MOUSE BRAIN IN RELATION TO GOLD THIOGLUCOSE OBESITY

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Debons, A.F.; Silver, L.; Cronkite, E.P.

    1962-04-01

    Administration of gold thioglucose led to the development of hyperphagia and obesity in mice; this confirmed findings by previous investigators. By employing neutron activation analysis and radioautography, it was observed that this syndrome was associated with focal accumulation of gold in the hypothalamus. Animals treated with gold thiomalate failed to show any hypothalamic Iocalization of gold radioautographically or any evidence of the syndrome of hyperphagla and obesity. In additlon, other foci of gold locallzation were found in gold thioglucose-treated but not in the gold thiomalate-treated animals. Gamma spectroscopy studies made possible quantitative measurements of the gold content ln the brainsmore » of both treated groups. Gold thioglucose-treated as well as gold thiomalate-treated animals had appreciable quantities of gold in the brain proper. Phosphorus-32 generated by neutron activation of the sulfur moiety of gold thioglucose proved to be insigniflcant in its contribution to the radioautographic flndings. Implication of the above findings for the glucostatic theory of appetite regulation is discussed. (auth)« less

  12. Should conventional angiography be the gold standard for carotid stenosis?

    PubMed

    Zhang, Wayne W; Harris, Linda M; Dryjski, Maciej L

    2006-12-01

    To compare conventional angiography (CA) and rotational angiography (RA) to assess the degree of angiographically-measured stenosis versus cross-sectional area (CSA) stenosis in an in vitro carotid model. Various grades of stenosis were created by adhering different amounts of silicone rubber sealant onto the inner wall of clear, radiolucent tubes. Following 2- and 3-projection CA and 20-projection RA, the tubes were transected at the actual maximum stenosis. The cross-sectional areas were digitally photographed, and CSA stenosis was calculated using ImageJ planimeter software. The differences among CA, RA, and CSA stenosis measurements were compared statistically. There was no significant difference between RA and CSA stenosis measurements (p=0.46). Conventional angiography with 2 or 3 projections between 0 degrees and 90 degrees underestimated the severity of disease in 19 (63%) of 30 samples. The maximum stenosis percentage was significantly lower in CA versus RA (p<0.0001 in 2-projection, p<0.0003 in 3-projection) and in CA versus CSA stenosis (p<0.0004 in 2-projection, p<0.001 in 3-projection). The maximum stenosis percentages measured by RA were less than CSA stenosis in 5 (71.4%) of 7 tubes (p=NS) containing 50% to 69% stenoses. Eight tubes had mountain-shaped lesions, which was significantly overestimated by RA (11.5%+/-9.7%, p<0.012). CA with 2 or 3 projections significantly underestimates the maximum stenosis in an in vitro model. RA may overestimate disease in patients with mountain-shaped plaques and may underestimate disease if the stenosis is <70%. Our data suggest that CA should not be the gold standard for the qualification of carotid endarterectomy in asymptomatic patients, nor for vascular laboratory quality assurance analysis.

  13. Feasibility study of common electronic equipment for shuttle sortie experiment payloads

    NASA Technical Reports Server (NTRS)

    1974-01-01

    A study was conducted to determine the feasibility of using standardized electronic equipment on the space shuttle vehicle in an effort to reduce the cost estimates. The standards for Nuclear Instrument Modules (NIM) and CAMAC electronic equipment are presented and described. It was determined that the CAMAC electronic equipment was more suitable for use with the space shuttle systems. Specific applications of the CAMAC equipment are analyzed. Illustrations of the equipment and circuit diagrams of the subsystems are provided.

  14. 46 CFR 154.1005 - Equipment approval.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Equipment approval. 154.1005 Section 154.1005 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Electrical...

  15. 46 CFR 154.1005 - Equipment approval.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Equipment approval. 154.1005 Section 154.1005 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Electrical...

  16. 46 CFR 154.1005 - Equipment approval.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Equipment approval. 154.1005 Section 154.1005 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Electrical...

  17. 46 CFR 154.1005 - Equipment approval.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Equipment approval. 154.1005 Section 154.1005 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Electrical...

  18. 46 CFR 154.1005 - Equipment approval.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Equipment approval. 154.1005 Section 154.1005 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Electrical...

  19. Electrodeposition of gold particles on aluminum substrates containing copper.

    PubMed

    Olson, Tim S; Atanassov, Plamen; Brevnov, Dmitri A

    2005-01-27

    Electrodeposition of adhesive metal films on aluminum is traditionally preceded by the zincate process, which activates the aluminum surface. This paper presents an alternative approach for activation of aluminum by using films containing 99.5% aluminum and 0.5% copper. Aluminum/copper films are made amenable for subsequent electrodeposition by anodization followed by chemical etching of aluminum oxide. The electrodeposition of gold is monitored with electrochemical impedance spectroscopy (EIS). Analysis of EIS data suggests that electrodeposition of gold increases the interfacial capacitance from values typical for electrodes with thin oxide layers to values typical for metal electrodes. Scanning electron microscopy examination of aluminum/copper films following gold electrodeposition shows the presence of gold particles with densities of 10(5)-10(7) particles cm(-2). The relative standard deviation of mean particle diameters is approximately 25%. Evaluation of the micrographs suggests that the electrodeposition occurs by instantaneous nucleation followed by growth of three-dimensional semispherical particles. The gold particles, which are electrically connected to the conductive aluminum/copper film, support a reversible faradaic process for a soluble redox couple. The deposited gold particles are suitable for subsequent metallization of aluminum and fabrication of particle-type films with interesting catalytic, electrical, and optical properties.

  20. 30 CFR 75.523 - Electric face equipment; deenergization.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Electric face equipment; deenergization. 75.523... SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.523 Electric face equipment; deenergization. [Statutory Provision] An authorized representative of the...

  1. 30 CFR 75.523 - Electric face equipment; deenergization.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Electric face equipment; deenergization. 75.523... SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.523 Electric face equipment; deenergization. [Statutory Provision] An authorized representative of the...

  2. 30 CFR 75.523 - Electric face equipment; deenergization.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Electric face equipment; deenergization. 75.523... SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.523 Electric face equipment; deenergization. [Statutory Provision] An authorized representative of the...

  3. 30 CFR 75.523 - Electric face equipment; deenergization.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Electric face equipment; deenergization. 75.523... SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.523 Electric face equipment; deenergization. [Statutory Provision] An authorized representative of the...

  4. 30 CFR 75.523 - Electric face equipment; deenergization.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Electric face equipment; deenergization. 75.523... SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.523 Electric face equipment; deenergization. [Statutory Provision] An authorized representative of the...

  5. 41 CFR 50-204.7 - Personal protective equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CONTRACTS General Safety and Health Standards § 50-204.7 Personal protective equipment. Protective equipment, including personal protective equipment for eyes, face, head, and extremities, protective clothing... 41 Public Contracts and Property Management 1 2011-07-01 2009-07-01 true Personal protective...

  6. 41 CFR 50-204.7 - Personal protective equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CONTRACTS General Safety and Health Standards § 50-204.7 Personal protective equipment. Protective equipment, including personal protective equipment for eyes, face, head, and extremities, protective clothing... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Personal protective...

  7. Mechanisms of gold bioaccumulation by filamentous cyanobacteria from gold(III)-chloride complex.

    PubMed

    Lengke, Maggy F; Ravel, Bruce; Fleet, Michael E; Wanger, Gregory; Gordon, Robert A; Southam, Gordon

    2006-10-15

    The mechanisms of gold bioaccumulation by cyanobacteria (Plectonema boryanum UTEX 485) from gold(III)-chloride solutions have been studied at three gold concentrations (0.8,1.7, and 7.6 mM) at 25 degrees C, using both fixed-time laboratory and real-time synchrotron radiation absorption spectroscopy (XAS) experiments. Interaction of cyanobacteria with aqueous gold(III)-chloride initially promoted the precipitation of nanoparticles of amorphous gold(I)-sulfide at the cell walls, and finally deposited metallic gold in the form of octahedral (111) platelets (approximately 10 nm to 6 microm) near cell surfaces and in solutions. The XAS results confirm that the reduction mechanism of gold(III)-chloride to metallic gold by cyanobacteria involves the formation of an intermediate Au(I) species, gold(I)-sulfide.

  8. Civilian First Responder Decontamination Equipment Characteristics Survey Results

    DTIC Science & Technology

    2010-01-01

    EQUIPMENT CHARACTERISTICS SURVEY RESULTS Scott Kooistra Shawn Bowen John Walther PROGRAM INTEGRATION DIRECTORATE Michael B. DeZearn ENGINEERING...COVERED (From - To) Mar 2007-Feb 2008 4. TITLE AND SUBTITLE Civilian First Responder Decontamination Equipment Characteristics Survey Results 5a...Department of Homeland Security/National Institute of Standards and Technology (DHS/NIST) Standards Development Team to develop a survey to

  9. Nanomolar Trace Metal Analysis of Copper at Gold Microband Arrays

    NASA Astrophysics Data System (ADS)

    Wahl, A.; Dawson, K.; Sassiat, N.; Quinn, A. J.; O'Riordan, A.

    2011-08-01

    This paper describes the fabrication and electrochemical characterization of gold microband electrode arrays designated as a highly sensitive sensor for trace metal detection of copper in drinking water samples. Gold microband electrodes have been routinely fabricated by standard photolithographic methods. Electrochemical characterization were conducted in 0.1 M H2SO4 and found to display characteristic gold oxide formation and reduction peaks. The advantages of gold microband electrodes as trace metal sensors over currently used methods have been investigated by employing under potential deposition anodic stripping voltammetry (UPD-ASV) in Cu2+ nanomolar concentrations. Linear correlations were observed for increasing Cu2+ concentrations from which the concentration of an unknown sample of drinking water was estimated. The results obtained for the estimation of the unknown trace copper concentration in drinking was in good agreement with expected values.

  10. Advanced Placement and International Baccalaureate: Do They Deserve Gold Star Status?

    ERIC Educational Resources Information Center

    Byrd, Sheila

    2007-01-01

    For many people committed to strong academic standards, the "advanced" high school courses offered through the College Board's Advanced Placement program and, increasingly, the Diploma Programme of the International Baccalaureate Organisation (IBO) represent the curricular gold standard for secondary education. Admissions directors and…

  11. Patterning of oxide-hardened gold black by photolithography and metal lift-off

    NASA Astrophysics Data System (ADS)

    Panjwani, Deep; Yesiltas, Mehmet; Nath, Janardan; Maukonen, D. E.; Rezadad, Imen; Smith, Evan M.; Peale, R. E.; Hirschmugl, Carol; Sedlmair, Julia; Wehlitz, Ralf; Unger, Miriam; Boreman, Glenn

    2014-01-01

    A method to pattern infrared-absorbing gold black by conventional photolithography and lift-off is described. A photo-resist pattern is developed on a substrate by standard photolithography. Gold black is deposited over the whole by thermal evaporation in an inert gas at ˜1 Torr. SiO2 is then deposited as a protection layer by electron beam evaporation. Lift-off proceeds by dissolving the photoresist in acetone. The resulting sub-millimeter size gold black patterns that remain on the substrate retain high infrared absorption out to ˜5 μm wavelength and exhibit good mechanical stability. This technique allows selective application of gold black coatings to the pixels of thermal infrared imaging array detectors.

  12. Medical equipment management strategies.

    PubMed

    Wang, Binseng; Furst, Emanuel; Cohen, Ted; Keil, Ode R; Ridgway, Malcolm; Stiefel, Robert

    2006-01-01

    Clinical engineering professionals need to continually review and improve their management strategies in order to keep up with improvements in equipment technology, as well as with increasing expectations of health care organizations. In the last 20 years, management strategies have evolved from the initial obsession with electrical safety to flexible criteria that fit the individual institution's needs. Few hospitals, however, are taking full advantage of the paradigm shift offered by the evolution of joint Commission standards. The focus should be on risks caused by equipment failure, rather than on equipment with highest maintenance demands. Furthermore, it is not enough to consider risks posed by individual pieces of equipment to individual patients. It is critical to anticipate the impact of an equipment failure on larger groups of patients, especially when dealing with one of a kind, sophisticated pieces of equipment that are required to provide timely and accurate diagnoses for immediate therapeutic decisions or surgical interventions. A strategy for incorporating multiple criteria to formulate appropriate management strategies is provided in this article.

  13. Unreliability and error in the military's "gold standard" measure of sexual harassment by education and gender.

    PubMed

    Murdoch, Maureen; Pryor, John B; Griffin, Joan M; Ripley, Diane Cowper; Gackstetter, Gary D; Polusny, Melissa A; Hodges, James S

    2011-01-01

    The Department of Defense's "gold standard" sexual harassment measure, the Sexual Harassment Core Measure (SHCore), is based on an earlier measure that was developed primarily in college women. Furthermore, the SHCore requires a reading grade level of 9.1. This may be higher than some troops' reading abilities and could generate unreliable estimates of their sexual harassment experiences. Results from 108 male and 96 female soldiers showed that the SHCore's temporal stability and alternate-forms reliability was significantly worse (a) in soldiers without college experience compared to soldiers with college experience and (b) in men compared to women. For men without college experience, almost 80% of the temporal variance in SHCore scores was attributable to error. A plain language version of the SHCore had mixed effects on temporal stability depending on education and gender. The SHCore may be particularly ill suited for evaluating population trends of sexual harassment in military men without college experience.

  14. A general approach for sample size calculation for the three-arm 'gold standard' non-inferiority design.

    PubMed

    Stucke, Kathrin; Kieser, Meinhard

    2012-12-10

    In the three-arm 'gold standard' non-inferiority design, an experimental treatment, an active reference, and a placebo are compared. This design is becoming increasingly popular, and it is, whenever feasible, recommended for use by regulatory guidelines. We provide a general method to calculate the required sample size for clinical trials performed in this design. As special cases, the situations of continuous, binary, and Poisson distributed outcomes are explored. Taking into account the correlation structure of the involved test statistics, the proposed approach leads to considerable savings in sample size as compared with application of ad hoc methods for all three scale levels. Furthermore, optimal sample size allocation ratios are determined that result in markedly smaller total sample sizes as compared with equal assignment. As optimal allocation makes the active treatment groups larger than the placebo group, implementation of the proposed approach is also desirable from an ethical viewpoint. Copyright © 2012 John Wiley & Sons, Ltd.

  15. On the creation of a clinical gold standard corpus in Spanish: Mining adverse drug reactions.

    PubMed

    Oronoz, Maite; Gojenola, Koldo; Pérez, Alicia; de Ilarraza, Arantza Díaz; Casillas, Arantza

    2015-08-01

    The advances achieved in Natural Language Processing make it possible to automatically mine information from electronically created documents. Many Natural Language Processing methods that extract information from texts make use of annotated corpora, but these are scarce in the clinical domain due to legal and ethical issues. In this paper we present the creation of the IxaMed-GS gold standard composed of real electronic health records written in Spanish and manually annotated by experts in pharmacology and pharmacovigilance. The experts mainly annotated entities related to diseases and drugs, but also relationships between entities indicating adverse drug reaction events. To help the experts in the annotation task, we adapted a general corpus linguistic analyzer to the medical domain. The quality of the annotation process in the IxaMed-GS corpus has been assessed by measuring the inter-annotator agreement, which was 90.53% for entities and 82.86% for events. In addition, the corpus has been used for the automatic extraction of adverse drug reaction events using machine learning. Copyright © 2015 Elsevier Inc. All rights reserved.

  16. Distribution of copper, silver and gold during thermal treatment with brominated flame retardants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Oleszek, Sylwia, E-mail: sylwia_oleszek@yahoo.com; Institute of Environmental Engineering of the Polish Academy of Sciences, 34 M. Sklodowska-Curie St., 41-819 Zabrze; Grabda, Mariusz, E-mail: mariusz@mail.tagen.tohoku.ac.jp

    2013-09-15

    Highlights: • Copper, silver and gold during thermal treatment with brominated flame retardants. • Distribution of copper, silver and gold during thermal processing. • Thermodynamic considerations of the bromination reactions. - Abstract: The growing consumption of electric and electronic equipment results in creating an increasing amount of electronic waste. The most economically and environmentally advantageous methods for the treatment and recycling of waste electric and electronic equipment (WEEE) are the thermal techniques such as direct combustion, co-combustion with plastic wastes, pyrolysis and gasification. Nowadays, this kind of waste is mainly thermally treated in incinerators (e.g. rotary kilns) to decompose themore » plastics present, and to concentrate metals in bottom ash. The concentrated metals (e.g. copper, precious metals) can be supplied as a secondary raw material to metal smelters, while the pyrolysis of plastics allows the recovery of fuel gases, volatilising agents and, eventually, energy. Indeed, WEEE, such as a printed circuit boards (PCBs) usually contains brominated flame retardants (BFRs). From these materials, hydrobromic acid (HBr) is formed as a product of their thermal decomposition. In the present work, the bromination was studied of copper, silver and gold by HBr, originating from BFRs, such as Tetrabromobisphenol A (TBBPA) and Tetrabromobisphenol A-Tetrabromobisophenol A diglycidyl ether (TTDE) polymer; possible volatilization of the bromides formed was monitored using a thermo-gravimetric analyzer (TGA) and a laboratory-scale furnace for treating samples of metals and BFRs under an inert atmosphere and at a wide range of temperatures. The results obtained indicate that up to about 50% of copper and silver can evolve from sample residues in the form of volatile CuBr and AgBr above 600 and 1000 °C, respectively. The reactions occur in the molten resin phase simultaneously with the decomposition of the brominated resin

  17. Extraction of gold (Au) particles from sea water by Delftia Acidovorans microbes

    NASA Astrophysics Data System (ADS)

    Yusoff, A. H. M.; Nading, M. E.; Salimi, M. N.

    2017-10-01

    Gold-mining activities have been an issue, especially when it involves in contamination of chemicals, for example arsenic and mercury. However, despite of these hazards, gold-mining activities are still being conducted. This is because the gold is worth, regardless of the problems. Gold-mining, as known needs a very large area of land, or site plant. Vast amount of labor force, mechanical force and fund are a must in order for the mining process to be continued. High demand of gold, made gold-mining industries as ones of the most profitable industries in the world. Thus, this has encouraged another alternative way to extract gold. At the mining site, researchers found that biomineralization of gold by Delftia acidovorans can be conducted. How it is done still cannot be understood. It is said that the bacteria secretes secondary metabolites, Delftibactin as a defensive mechanism against the toxicity of the soluble gold. Researchers try to find another source of elemental gold besides of the earth’s core. The options are either lava of a volcano or ocean. Here, the focus is seawater. The problem of seawater is that its composition still not yet to be proved. Dissolve gold existed as gold chloride in seawater, but in a very small amount. So, the gold separation should be focused, in order to make this process to be a successful one. Factors such as depth, climate, region, temperature need to be considered. If this difference affecting the separating process, standardized seawater composition have to be proposed.

  18. Self-Assembled Monolayers of Dithiophosphinic Acids on Gold

    NASA Astrophysics Data System (ADS)

    San Juan, Ronan Roca

    This dissertation reports the synthesis of derivatives of dithiophosphinic acids (R1R2DTPAs), and the formation and characterization of DTPA SAMs on gold to build a knowledge base on their nature of binding, organization of the alkyl chains and electrochemical barrier properties. The binding of DTPA molecules on gold depends on the morphology of the gold film: They bind in a mixed monodentate and bidentate modes on standard as-deposited (As-Dep) gold, while they fully chelate on smoother template-stripped (TS) gold. Chapter 2 focuses on van der Waals interactions of various alkyl chain lengths of symmetrical R2DTPA SAMs, which increase with increasing chain lengths similar to those of the analogous n-alkanethiol SAMs, but with alkyl chains that are generally less dense than those of n-alkanethiol SAMs. Chapter 3 addresses why the DTPA compounds do not chelate on the standard As-Dep gold by comparing (C16)2DTPA SAM to (C16 )2DDP SAM. Here, side chain crystallinity stabilizes DTPA SAM structure at the expense of chelation of the DTPA molecules, which leads to a mixture of bidentate and monodentate DTPA molecules, whereas the increased flexibility of the chains in DDP due to the oxygen atoms retains chelation of the DDP molecules. Chapter 4 focuses on the SAMs formed from RlongRshort DTPAs, which shows that the length of the short chain spacer affects SAM packing density and thickness. The SAMs of these molecules also show homogeneous mixing of Rlong and Rshort chains. Chapter 5 investigates PhRDTPA SAMs in preparation for molecular junction studies. The chelation of PhRDTPA molecules on TS gold allows the PhRDTPAs to act as molecular alligator clips. The length of the alkyl chains controls the density of the phenyl group and they fill in the voids between adsorbates to prevent electrical shorting. Finally, Chapter 6 incorporates OH tail group(s) to control the wettability of DTPA SAMs. The presence of OH groups in DTPAs forms hydrophilic SAMs. The symmetrical OH

  19. 30 CFR 72.700 - Respiratory equipment; respirable dust.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Respiratory equipment; respirable dust. 72.700... SAFETY AND HEALTH HEALTH STANDARDS FOR COAL MINES Miscellaneous § 72.700 Respiratory equipment; respirable dust. (a) Respiratory equipment approved by NIOSH under 42 CFR part 84 shall be made available to...

  20. 30 CFR 75.1916 - Operation of diesel-powered equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Operation of diesel-powered equipment. 75.1916... SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Diesel-Powered Equipment § 75.1916 Operation of diesel-powered equipment. (a) Diesel-powered equipment shall be operated at a speed that is...

  1. 30 CFR 75.1916 - Operation of diesel-powered equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Operation of diesel-powered equipment. 75.1916... SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Diesel-Powered Equipment § 75.1916 Operation of diesel-powered equipment. (a) Diesel-powered equipment shall be operated at a speed that is...

  2. Gold and gold-iron oxide magnetic glyconanoparticles: synthesis, characterization and magnetic properties.

    PubMed

    de la Fuente, Jesús M; Alcántara, David; Eaton, Peter; Crespo, Patricia; Rojas, Teresa C; Fernandez, Asunción; Hernando, Antonio; Penadés, Soledad

    2006-07-06

    The preparation, characterization and the magnetic properties of gold and gold-iron oxide glyconanoparticles (GNPs) are described. Glyconanoparticles were prepared in a single step procedure in the presence of aqueous solution of thiol functionalized neoglycoconjugates and either gold salts or both gold and iron salts. Neoglycoconjugates of lactose and maltose disaccharides with different linkers were used. Iron-free gold or gold-iron oxide GNPs with controlled gold-iron ratios were obtained. The average core-size diameters are in the range of 1.5-2.5 nm. The GNPs are fully characterized by (1)H NMR spectrometry, transmission electron microscopy (TEM), and UV-vis and X-ray absorption (XAS) spectroscopies. Inductive plasma-atomic emission spectrometry (ICP) and elemental analysis gave the average number of neoglycoconjugates per cluster. The magnetic properties were measured in a SQUID magnetometer. The most remarkable results was the observation of a permanent magnetism up to room temperature in the iron-free gold GNPs, that was not present in the corresponding gold-iron oxide GNPs.

  3. Electroanalytical sensing of chromium(III) and (VI) utilising gold screen printed macro electrodes.

    PubMed

    Metters, Jonathan P; Kadara, Rashid O; Banks, Craig E

    2012-02-21

    We report the fabrication of gold screen printed macro electrodes which are electrochemically characterised and contrasted to polycrystalline gold macroelectrodes with their potential analytical application towards the sensing of chromium(III) and (VI) critically explored. It is found that while these gold screen printed macro electrodes have electrode kinetics typically one order of magnitude lower than polycrystalline gold macroelectrodes as is measured via a standard redox probe, in terms of analytical sensing, these gold screen printed macro electrodes mimic polycrystalline gold in terms of their analytical performance towards the sensing of chromium(III) and (VI), whilst boasting additional advantages over the macro electrode due to their disposable one-shot nature and the ease of mass production. An additional advantage of these gold screen printed macro electrodes compared to polycrystalline gold is the alleviation of the requirement to potential cycle the latter to form the required gold oxide which aids in the simplification of the analytical protocol. We demonstrate that gold screen printed macro electrodes allow the low micro-molar sensing of chromium(VI) in aqueous solutions over the range 10 to 1600 μM with a limit of detection (3σ) of 4.4 μM. The feasibility of the analytical protocol is also tested through chromium(VI) detection in environmental samples.

  4. Tiopronin Gold Nanoparticle Precursor Forms Aurophilic Ring Tetramer

    PubMed Central

    Simpson, Carrie A.; Farrow, Christopher L.; Tian, Peng; Billinge, Simon J.L.; Huffman, Brian J.; Harkness, Kellen M.; Cliffel, David E.

    2010-01-01

    In the two step synthesis of thiolate-monolayer protected clusters (MPCs), the first step of the reaction is a mild reduction of gold(III) by thiols that generates gold(I) thiolate complexes as intermediates. Using tiopronin (Tio) as the thiol reductant, the characterization of the intermediate Au4Tio4 complex was accomplished with various analytical and structural techniques. Nuclear magnetic resonance (NMR), elemental analysis, thermogravimetric analysis (TGA), and matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS) were all consistent with a cyclic gold(I)-thiol tetramer structure, and final structural analysis was gathered through the use of powder diffraction and pair distribution functions (PDF). Crystallographic data has proved challenging for almost all previous gold(I)-thiolate complexes. Herein, a novel characterization technique when combined with standard analytical assessment to elucidate structure without crystallographic data proved invaluable to the study of these complexes. This in conjunction with other analytical techniques, in particular mass spectrometry, can elucidate a structure when crystallographic data is unavailable. In addition, luminescent properties provided evidence of aurophilicity within the molecule. The concept of aurophilicity has been introduced to describe a select group of gold-thiolate structures, which possess unique characteristics, mainly red photoluminescence and a distinct Au-Au intramolecular distance indicating a weak metal-metal bond as also evidenced by the structural model of the tetramer. Significant features of both the tetrameric and aurophilic properties of the intermediate gold(I) tiopronin complex are retained after borohydride reduction to form the MPC, including gold(I) tiopronin partial rings as capping motifs, or “staples”, and weak red photoluminescence that extends into the Near Infrared region. PMID:21067183

  5. A gold standard method for the evaluation of antibody-based materials functionality: Approach to forced degradation studies.

    PubMed

    Coussot, Gaëlle; Le Postollec, Aurélie; Faye, Clément; Dobrijevic, Michel

    2018-04-15

    The scope of this paper is to present a gold standard method to evaluate functional activity of antibody (Ab)-based materials during the different phases of their development, after their exposure to forced degradations or even during routine quality control. Ab-based materials play a central role in the development of diagnostic devices, for example, for screening or therapeutic target characterization, in formulation development, and in novel micro(nano)technology approaches to develop immunosensors useful for the analysis of trace substances in pharmaceutical and food industries, clinical and environmental fields. A very important aspect in diagnostic device development is the construction of its biofunctional surfaces. These Ab surfaces require biocompatibility, homogeneity, stability, specificity and functionality. Thus, this work describes the validation and applications of a unique ligand binding assay to directly perform the quantitative measurement of functional Ab binding sites immobilized on the solid surfaces. The method called Antibody Anti-HorseRadish Peroxidase (A2HRP) method, uses a covalently coated anti-HRP antibody (anti-HRP Ab) and does not need for a secondary Ab during the detection step. The A2HRP method was validated and gave reliable results over a wide range of absorbance values. Analyzed validation criteria were fulfilled as requested by the food and drug administration (FDA) and European Medicines Agency (EMA) guidance for the validation of bioanalytical methods with 1) an accuracy mean value within +15% of the nominal value; 2) the within-assay precision less than 7.1%, and 3) the inter-day variability under 12.1%. With the A2HRP method, it is then possible to quantify from 0.04 × 10 12 to 2.98 × 10 12 functional Ab binding sites immobilized on the solid surfaces. A2HRP method was validated according to FDA and EMA guidance, allowing the creation of a gold standard method to evaluate Ab surfaces for their resistance under

  6. 46 CFR 154.1400 - Safety equipment: All vessels.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Safety equipment: All vessels. 154.1400 Section 154.1400 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Safety Equipment § 154.1400 Safety...

  7. 46 CFR 154.1400 - Safety equipment: All vessels.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Safety equipment: All vessels. 154.1400 Section 154.1400 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Safety Equipment § 154.1400 Safety...

  8. Gold--a controversial sensitizer. European Environmental and Contact Dermatitis Research Group.

    PubMed

    Bruze, M; Andersen, K E

    1999-06-01

    Until recently, gold allergy was considered to be extremely rare. Gold has been used and worshipped for thousands of years without any obvious complaints of skin problems, either in those participating in mining and other ways of prospecting, or in those wearing jewellery. When studies on contact allergy to gold sodium thiosulfate were published at the beginning of the 1990s, the allergic nature of the reported positive patch test reactions to gold was questioned. The major argument for such questioning was the lack of demonstrable clinical relevance in most positive reactors. A major reason for the questioning may have been confusion in differentiating between contact allergy and allergic contact dermatitis. To arrive at a diagnosis of allergic contact dermatitis, 3 steps have, in principle, to be fulfilled: (i) establishment of contact allergy; (ii) demonstration of present exposure; (iii) assessment of clinical relevance, i.e., causing or aggravating a contact dermatitis. In this paper, these steps are discussed with regard to gold. With our present knowledge of contact allergy-allergic contact dermatitis, we do not recommend including gold sodium thiosulfate in the standard series. It should be applied for scientific purposes and when allergic contact dermatitis from gold is suspected.

  9. Testing and Evaluation of Passive Radiation Detection Equipment for Homeland Security

    DOE PAGES

    West, David L.; Wood, Nathan L.; Forrester, Christina D.

    2017-12-01

    This article is concerned with test and evaluation methods for passive radiation detection equipment used in homeland security applications. The different types of equipment used in these applications are briefly reviewed and then test and evaluation methods discussed. The primary emphasis is on the test and evaluation standards developed by the American National Standards Institute’s N42 committees. Commonalities among the standards are then reviewed as well as examples of unique aspects for specific equipment types. Throughout, sample test configurations and results from testing and evaluation at Oak Ridge National Laboratory are given. The article concludes with a brief discussion ofmore » typical tests and evaluations not covered by the N42 standards and some examples of test and evaluation that involve the end users of the equipment.« less

  10. Testing and Evaluation of Passive Radiation Detection Equipment for Homeland Security

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    West, David L.; Wood, Nathan L.; Forrester, Christina D.

    This article is concerned with test and evaluation methods for passive radiation detection equipment used in homeland security applications. The different types of equipment used in these applications are briefly reviewed and then test and evaluation methods discussed. The primary emphasis is on the test and evaluation standards developed by the American National Standards Institute’s N42 committees. Commonalities among the standards are then reviewed as well as examples of unique aspects for specific equipment types. Throughout, sample test configurations and results from testing and evaluation at Oak Ridge National Laboratory are given. The article concludes with a brief discussion ofmore » typical tests and evaluations not covered by the N42 standards and some examples of test and evaluation that involve the end users of the equipment.« less

  11. Origin of the transition voltage in gold-vacuum-gold atomic junctions.

    PubMed

    Wu, Kunlin; Bai, Meilin; Sanvito, Stefano; Hou, Shimin

    2013-01-18

    The origin and the distance dependence of the transition voltage of gold-vacuum-gold junctions are investigated by employing first-principles quantum transport simulations. Our calculations show that atomic protrusions always exist on the electrode surface of gold-vacuum-gold junctions fabricated using the mechanically controllable break junction (MCBJ) method. The transition voltage of these gold-vacuum-gold junctions with atomically sharp electrodes is determined by the local density of states (LDOS) of the apex gold atom on the electrode surface rather than by the vacuum barrier shape. More specifically, the absolute value of the transition voltage roughly equals the rising edge of the LDOS peak contributed by the 6p atomic orbitals of the gold atoms protruding from the electrode surface, whose local Fermi level is shifted downwards when a bias voltage is applied. Since the LDOS of the apex gold atom depends strongly on the exact shape of the electrode, the transition voltage is sensitive to the variation of the atomic configuration of the junction. For asymmetric junctions, the transition voltage may also change significantly depending on the bias polarity. Considering that the occurrence of the transition voltage requires the electrode distance to be larger than a critical value, the interaction between the two electrodes is actually rather weak. Consequently, the LDOS of the apex gold atom is mainly determined by its local atomic configuration and the transition voltage only depends weakly on the electrode distance as observed in the MCBJ experiments.

  12. 32 CFR 34.21 - Real property and equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Real property and equipment. 34.21 Section 34.21... Requirements Property Standards § 34.21 Real property and equipment. (a) Prior approval for acquisition with Federal funds. Recipients may purchase real property or equipment in whole or in part with Federal funds...

  13. 32 CFR 34.21 - Real property and equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false Real property and equipment. 34.21 Section 34.21... Requirements Property Standards § 34.21 Real property and equipment. (a) Prior approval for acquisition with Federal funds. Recipients may purchase real property or equipment in whole or in part with Federal funds...

  14. 32 CFR 34.21 - Real property and equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Real property and equipment. 34.21 Section 34.21... Requirements Property Standards § 34.21 Real property and equipment. (a) Prior approval for acquisition with Federal funds. Recipients may purchase real property or equipment in whole or in part with Federal funds...

  15. 32 CFR 34.21 - Real property and equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 1 2014-07-01 2014-07-01 false Real property and equipment. 34.21 Section 34.21... Requirements Property Standards § 34.21 Real property and equipment. (a) Prior approval for acquisition with Federal funds. Recipients may purchase real property or equipment in whole or in part with Federal funds...

  16. 32 CFR 34.21 - Real property and equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false Real property and equipment. 34.21 Section 34.21... Requirements Property Standards § 34.21 Real property and equipment. (a) Prior approval for acquisition with Federal funds. Recipients may purchase real property or equipment in whole or in part with Federal funds...

  17. Remote sensing of the coastal ocean with standard geodetic GNSS-equipment

    NASA Astrophysics Data System (ADS)

    Löfgren, J. S.; Haas, R.; Larson, K. M.; Scherneck, H.-G.

    2012-04-01

    We use standard geodetic Global Navigation Satellite System (GNSS) equipment to perform remote sensing measurements of the coastal ocean. This is done by a so-called GNSS-based tide gauge that uses both direct GNSS-signals and GNSS-signals that are reflected off the sea surface. Our installation is located at the Onsala Space Observatory (OSO) at the west coast of Sweden and consists of a zenith-looking Right Hand Circularly Polarized (RHCP) and a nadir-looking Left Hand Circularly Polarized (LHCP) antenna. Each antenna is connected to a standard geodetic-type GNSS-receiver. We applied two different analysis strategies to our GNSS data set. The first strategy is based on a traditional geodetic differential analysis [Löfgren et al., 2011] and makes use of the data from both receivers; connected to the zenith and the nadir looking antennae. This approach results in local sea level that is automatically corrected for land motion, meaning that the GNSS-based tide gauge can provide reliable sea-level estimates even in tectonic active regions. The second strategy focuses on the Signal-to-Noise Ratio (SNR) recorded with the receiver connected to the zenith-looking antenna [Larson et al., 2011]. The SNR is affected by multipath originating from the sea surface reflections. Analysis of the SNR data allows to determine the distance between the antenna and the reflecting surface, and thus to measure sea surface height. Results from both analysis strategies are compared to independently observed sea-level data from two stilling-well gauges operated by the Swedish Meteorological and Hydrological Institute (SMHI), which lie in a distance of several km from OSO. The root-mean-square agreement between the different time series of several month's length is on the order of 5 cm and better. These results indicate the large potential for using coastal GNSS-sites for the monitoring of the coastal ocean.

  18. Laser-driven shock compression of gold foam in the terapascal pressure range

    NASA Astrophysics Data System (ADS)

    Liu, Wei; Duan, Xiaoxi; Jiang, Shaoen; Wang, Zhebin; Sun, Liang; Liu, Hao; Yang, Weiming; Zhang, Huan; Ye, Qing; Wang, Peng; Li, Yulong; Yi, Lin; Dong, Suo

    2018-06-01

    Shock compression experiments are carried out on gold foam with an initial density of 3.2 g/cm3 through indirectly laser-driven shock waves at the SG-III prototype laser facility. The impedance-matching technique is applied to determine the equation-of-state (EOS) data of the shocked gold foam. A passive shock breakout diagnostic system is employed to obtain the shock velocities in both the standard material and gold foam. The gold foams are compressed to a maximum density of 20 g/cm3 under a shock pressure of about 2 TPa. The effects of the unsteadiness of shock waves on the EOS measurement are quantitatively analyzed and corrected. The correction of unsteady waves, as well as the good planarity of the shock waves and the low preheating of the gold foam, contributes high-confidence EOS data for the gold foam. The corrected experimental data are compared with the Hugoniot states from the SESAME library. The comparison suggests that the database is suitable for describing the states of gold foam with an initial density of 3.2 g/cm3 under a pressure of about 2 TPa.

  19. 7 CFR 58.229 - Filler and packaging equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... construction and all parts, including valves and filler heads accessible for cleaning. New or replacement equipment should comply with the 3-A Sanitary Standards for equipment for Packaging Dry Milk and Dry Milk...

  20. Portable X-ray diffractometer equipped with XRF for archaeometry

    NASA Astrophysics Data System (ADS)

    Uda, M.; Ishizaki, A.; Satoh, R.; Okada, K.; Nakajima, Y.; Yamashita, D.; Ohashi, K.; Sakuraba, Y.; Shimono, A.; Kojima, D.

    2005-09-01

    A portable X-ray diffractometer equipped with an X-ray fluorescence spectrometer was improved so as to get a diffraction pattern and a fluorescence spectrum simultaneously in air from one and the same small area on a specimen. Here, diffraction experiments were performed in two modes, i.e. an angle rotation mode and an energy dispersive mode. In the latter a diffraction pattern and a fluorescence spectrum were simultaneously recorded in a short time, 100 s or less, on one display. The diffractometer was tested in the field to confirm its performance. Targets chosen for this purpose were a bronze mirror from the Eastern Han Dynasty (25-220), and a stupa and its pedestal which are part of the painted statue of "Tamonten holding a stupa" from the Heian Period (794-1192), enshrined in the Engyouji temple founded in 996. The bronze mirror was identified as a product of the Han Dynasty from its chemical composition and the existence of the δ phase in the Cu-Sn alloy. The stupa and its pedestal were decorated with gold powder and gold leaf, respectively. From the XRF data of the pedestal, the underlying layer of gold leaf seems to have been painted with emerald green.

  1. 30 CFR 75.1908 - Nonpermissible diesel-powered equipment; categories.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Nonpermissible diesel-powered equipment... LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Diesel-Powered Equipment § 75.1908 Nonpermissible diesel-powered equipment; categories. (a) Heavy-duty diesel-powered...

  2. 30 CFR 75.1908 - Nonpermissible diesel-powered equipment; categories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Nonpermissible diesel-powered equipment... LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Diesel-Powered Equipment § 75.1908 Nonpermissible diesel-powered equipment; categories. (a) Heavy-duty diesel-powered...

  3. Is It Real Gold?

    ERIC Educational Resources Information Center

    Harris, Harold H.

    1999-01-01

    Features acid tests for determining whether jewelry is "real" gold or simply gold-plated. Describes the carat system of denoting gold content and explains how alloys are used to create various shades of gold jewelry. Addresses the question of whether gold jewelry can turn a wearer's skin green by considering various oxidation reactions.…

  4. Evaluation of human exposure to complex waveform magnetic fields generated by arc-welding equipment according to European safety standards.

    PubMed

    Zoppetti, Nicola; Bogi, Andrea; Pinto, Iole; Andreuccetti, Daniele

    2015-02-01

    In this paper, a procedure is described for the assessment of human exposure to magnetic fields with complex waveforms generated by arc-welding equipment. The work moves from the analysis of relevant guidelines and technical standards, underlining their strengths and their limits. Then, the procedure is described with particular attention to the techniques used to treat complex waveform fields. Finally, the procedure is applied to concrete cases encountered in the workplace. The discussion of the results highlights the critical points in the procedure, as well as those related to the evolution of the technical and exposure standards. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  5. 30 CFR 75.811 - High-voltage underground equipment; grounding.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...-voltage equipment supplying power to such equipment receiving power from resistance grounded systems shall... 30 Mineral Resources 1 2010-07-01 2010-07-01 false High-voltage underground equipment; grounding... COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Underground High-Voltage...

  6. 78 FR 54197 - Energy Efficiency Program for Commercial and Industrial Equipment: Energy Conservation Standards...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-03

    .... EERE-2013-BT-STD-0030] RIN 1904-AD01 Energy Efficiency Program for Commercial and Industrial Equipment... Certain Industrial Equipment,'' a program covering certain commercial and industrial equipment (hereafter... (AEMTCA), Public Law 112-210 (Dec. 18, 2012). EPCA covers many types of commercial and industrial...

  7. 30 CFR 75.1722 - Mechanical equipment guards.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Mechanical equipment guards. 75.1722 Section 75.1722 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Miscellaneous § 75.1722 Mechanical equipment...

  8. 30 CFR 56.4230 - Self-propelled equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....4230 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Fire Prevention and Control Firefighting Equipment § 56.4230 Self-propelled equipment. (a)(1) Whenever a fire or its effects...

  9. 47 CFR 80.225 - Requirements for selective calling equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... selective calling (DSC) equipment and selective calling equipment installed in ship and coast stations, and...-STD, “RTCM Recommended Minimum Standards for Digital Selective Calling (DSC) Equipment Providing... Class ‘D’ Digital Selective Calling (DSC)—Methods of testing and required test results,” March 2003. ITU...

  10. Gold paragenesis and chemistry at Batu Hijau, Indoneisa: implications for gold-rich porphyry copper deposits

    NASA Astrophysics Data System (ADS)

    Arif, J.; Baker, T.

    2004-10-01

    Gold is an important by-product in many porphyry-type deposits but the distribution and chemistry of gold in such systems remains poorly understood. Here we report the results of petrographic, electron microprobe, laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS), and flotation test studies of gold and associated copper sulfides within a paragenetic framework from the world-class Batu Hijau (914 mt @ 0.53% Cu, 0.40 g/t Au) porphyry copper gold deposit, Indonesia. Unlike many other porphyry copper gold deposits, early copper minerals (bornite digenite chalcocite) are well preserved at Batu Hijau and the chalcopyrite pyrite overprint is less developed. Hence, it provides an excellent opportunity to study the entire gold paragenesis of the porphyry system. In 105 polished thin sections, 699 native gold grains were identified. Almost all of the native gold grains occurred either within quartz veins, attached to sulfide, or as free gold along quartz or silicate grain boundaries. The native gold grains are dominantly round in shape and mostly 1 12 μm in size. The majority of gold was deposited during the formation of early ‘A’ veins and is dominantly associated with bornite rather than chalcopyrite. The petrographic and LA-ICP-MS study results indicate that in bornite-rich ores gold mostly occurs within copper sulfide grains as invisible gold (i.e., within the sulfide structure) or as native gold grains. In chalcopyrite-rich ores gold mostly occurs as native gold grains with lesser invisible gold. Petrographic observations also indicate a higher proportion of free gold (native gold not attached to any sulfide) in chalcopyrite-rich ores compared to bornite rich ores. The pattern of free gold distribution appears to correlate with the flotation test data, where the average gold recovery value from chalcopyrite-rich ores is consistently lower than bornite-rich ores. Our data suggest that porphyry copper-gold deposits with chalcopyrite-rich ores

  11. Enhancement of gold recovery using bioleaching from gold concentrate

    NASA Astrophysics Data System (ADS)

    Choi, S. H.; Cho, K. H.; Kim, B. J.; Choi, N. C.; Park, C. Y.

    2012-04-01

    The gold in refractory ores is encapsulated as fine particles (sometimes at a molecular level) in the crystal structure of the sulfide (typically pyrite with or without arsenopyrite) matrix. This makes it impossible to extract a significant amount of refractory gold by cyanidation since the cyanide solution cannot penetrate the pyrite/arsenopyrite crystals and dissolve gold particles, even after fine grinding. To effectively extract gold from these ores, an oxidative pretreatment is necessary to break down the sulfide matrix. The most popular methods of pretreatment include nitric acid oxidation, roasting, pressure oxidation and biological oxidation by microorganisms. This study investigated the bioleaching efficiency of Au concentrate under batch experimental conditions (adaptation cycles and chemical composition adaptation) using the indigenous acidophilic bacteria collected from gold mine leachate in Sunsin gold mine, Korea. We conducted the batch experiments at two different chemical composition (CuSO4 and ZnSO4), two different adaptation cycles 1'st (3 weeks) and 2'nd (6 weeks). The results showed that the pH in the bacteria inoculating sample decreased than initial condition and Eh increased. In the chemical composition adaptation case, the leached accumulation content of Fe and Pb was exhibited in CuSO4 adaptation bacteria sample more than in ZnSO4 adaptation bacteria samples, possibly due to pre-adaptation effect on chalcopyrite (CuFeS2) in gold concentrate. And after 21 days on the CuSO4 adaptation cycles case, content of Fe and Pb was appeared at 1'st adaptation bacteria sample(Fe - 1.82 and Pb - 25.81 times per control sample) lower than at 2'nd adaptation bacteria sample(Fe - 2.87 and Pb - 62.05 times per control sample). This study indicates that adaptation chemical composition and adaptation cycles can play an important role in bioleaching of gold concentrate in eco-/economic metallurgy process.

  12. Effects of Burning Conditions to the Formation of Gold Layer Photograph and Gold Layer Hologram

    NASA Astrophysics Data System (ADS)

    Kuge, Ken'ichi; Takahashi, Ataru; Harada, Takahito; Doi, Keiji; Sakai, Tomoko

    Burning stage from gold nanoparticles to gold layer in the formation process of gold-layer photograph using gold deposition development was investigated. The gelatin layer holding gold nanoparticles is carbonized at about 400°C and burned out until about 500°C. Because gold nanoparticles would be compressed only to vertical direction and then melt to form the gold layer, the gold-layer photograph still holds the high resolution. Gold nanoparaticles do not melt completely even at 900°C, and form continuous clusters of several hundred nm.

  13. Designing of a novel gold nanodumbbells SERS substrate for detection of prohibited colorants in drinks

    NASA Astrophysics Data System (ADS)

    Meng, Juan; Qin, Suhua; Zhang, Li; Yang, Liangbao

    2016-03-01

    It is reported that the use of gold nanodumbbells as surface-enhanced Raman spectroscopy (SERS) substrates for the detection of ultra-low levels of four different food colorants: sunset yellow, lemon yellow, orange II and chrysoidin. Gold nanodumbbells are suitable to on-site detection because which have a λmax of 785 nm that tune the surface plasmon resonance of the nanoparticles to the laser excitation wavelength of the Raman spectrometer equipped with a 785 nm diode laser. In order to investigate the on-site application of the gold nanodumbbells substrate, four pigments in the orange juice and coke were detected by the portable Raman instrument. The results showed that this novel SERS platform can be used as an effective method in detecting prohibited additive colorants in food. This SERS platform provides valuable and powerful analytical tool in real-world applications in food analysis.

  14. 40 CFR 1054.110 - What evaporative emission standards must my handheld equipment meet?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... must meet the permeation requirements for EPA Nonroad Fuel Lines or EPA Cold-Weather Fuel Lines as... that are not used in cold-weather equipment. For fuel lines used in cold-weather equipment, you may...

  15. Influence of gold content on copper oxidation from silver-gold-copper alloys

    NASA Astrophysics Data System (ADS)

    Swinbourne, D. R.; Barbante, G. G.; Strahan, A.

    1996-10-01

    In the final stages of the smelting of copper anode slimes, a silver alloy, known as “doré,” is produced. Oxidation refining is used to remove copper since this element interferes with subsequent electroparting of the small amounts of gold and platinum group metals in the doré. The gold content of doré can be greatly increased by gold scrap additions and this may affect the minimum achievable copper content of doré. In this work, silver-gold-copper alloys were oxidized by injecting pure oxygen at 1100 °C in the absence of any slag cover. For the gold contents expected in practice, the equilibrium copper content of the doré did not increase significantly as the gold content increased. However, at the other extreme of composition, the equilibrium copper content was a very strong function of the silver content of the gold bullion. The activity coefficient of copper in silver-gold alloys was calculated and compared to those predicted from a ternary subregular solution model of the system Ag-Au-Cu. Satisfactory agreement was found.

  16. Enrichment of Gold in Antimony Matte by Direct Smelting of Refractory Gold Concentrate

    NASA Astrophysics Data System (ADS)

    Yang, Tianzu; Xie, Boyi; Liu, Weifeng; Zhang, Duchao; Chen, Lin

    2018-04-01

    Conventional cyanidation technology achieves low gold recovery when used to process refractory gold concentrate. Based on the geochemical characteristics of gold deposit mineralization, a new method is proposed herein for gold enrichment in antimony matte by smelting of refractory gold concentrate. The effects of the FeO/SiO2 and CaO/SiO2 ratios, smelting temperature, and smelting time on the gold recovery were investigated in detail. The optimum conditions were determined to be FeO/SiO2 ratio of 1.2, CaO/SiO2 ratio of 0.4, smelting temperature of 1200°C, and smelting time of 45 min. The gold content in antimony matte and smelting slag was 96.68 and 1.13 g/t, respectively. The gold, antimony, and arsenic recovery was 97.72%, 26.89%, and 6.56%, respectively, with most of the antimony and arsenic volatilized into dust. Mineral liberation analyzer results showed that the antimony matte mainly consisted of FeS and FeO, with three phases, viz. FeAs, SbAs, and AuSb, embedded between them, indicating that gold was easily enriched with antimony and arsenic during smelting of refractory gold concentrate.

  17. Enrichment of Gold in Antimony Matte by Direct Smelting of Refractory Gold Concentrate

    NASA Astrophysics Data System (ADS)

    Yang, Tianzu; Xie, Boyi; Liu, Weifeng; Zhang, Duchao; Chen, Lin

    2018-06-01

    Conventional cyanidation technology achieves low gold recovery when used to process refractory gold concentrate. Based on the geochemical characteristics of gold deposit mineralization, a new method is proposed herein for gold enrichment in antimony matte by smelting of refractory gold concentrate. The effects of the FeO/SiO2 and CaO/SiO2 ratios, smelting temperature, and smelting time on the gold recovery were investigated in detail. The optimum conditions were determined to be FeO/SiO2 ratio of 1.2, CaO/SiO2 ratio of 0.4, smelting temperature of 1200°C, and smelting time of 45 min. The gold content in antimony matte and smelting slag was 96.68 and 1.13 g/t, respectively. The gold, antimony, and arsenic recovery was 97.72%, 26.89%, and 6.56%, respectively, with most of the antimony and arsenic volatilized into dust. Mineral liberation analyzer results showed that the antimony matte mainly consisted of FeS and FeO, with three phases, viz. FeAs, SbAs, and AuSb, embedded between them, indicating that gold was easily enriched with antimony and arsenic during smelting of refractory gold concentrate.

  18. 41 CFR 109-1.5108-1 - Equipment.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...-Personal Property Management Standards and Practices § 109-1.5108-1 Equipment. An individual property... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Equipment. 109-1.5108-1 Section 109-1.5108-1 Public Contracts and Property Management Federal Property Management Regulations...

  19. 41 CFR 109-1.5108-1 - Equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...-Personal Property Management Standards and Practices § 109-1.5108-1 Equipment. An individual property... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Equipment. 109-1.5108-1 Section 109-1.5108-1 Public Contracts and Property Management Federal Property Management Regulations...

  20. 41 CFR 109-1.5108-1 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...-Personal Property Management Standards and Practices § 109-1.5108-1 Equipment. An individual property... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Equipment. 109-1.5108-1 Section 109-1.5108-1 Public Contracts and Property Management Federal Property Management Regulations...

  1. 41 CFR 109-1.5108-1 - Equipment.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...-Personal Property Management Standards and Practices § 109-1.5108-1 Equipment. An individual property... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Equipment. 109-1.5108-1 Section 109-1.5108-1 Public Contracts and Property Management Federal Property Management Regulations...

  2. 41 CFR 109-1.5108-1 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...-Personal Property Management Standards and Practices § 109-1.5108-1 Equipment. An individual property... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Equipment. 109-1.5108-1 Section 109-1.5108-1 Public Contracts and Property Management Federal Property Management Regulations...

  3. 46 CFR 154.1852 - Air breathing equipment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Air breathing equipment. 154.1852 Section 154.1852... STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Operations § 154.1852 Air breathing equipment. (a) The master shall ensure that a licensed officer inspects the compressed air breathing...

  4. 46 CFR 154.1852 - Air breathing equipment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Air breathing equipment. 154.1852 Section 154.1852... STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Operations § 154.1852 Air breathing equipment. (a) The master shall ensure that a licensed officer inspects the compressed air breathing...

  5. 46 CFR 154.1852 - Air breathing equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Air breathing equipment. 154.1852 Section 154.1852... STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Operations § 154.1852 Air breathing equipment. (a) The master shall ensure that a licensed officer inspects the compressed air breathing...

  6. 46 CFR 154.1852 - Air breathing equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Air breathing equipment. 154.1852 Section 154.1852... STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Operations § 154.1852 Air breathing equipment. (a) The master shall ensure that a licensed officer inspects the compressed air breathing...

  7. 30 CFR 75.501-2 - Permissible electric face equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Permissible electric face equipment. 75.501-2... SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.501-2 Permissible electric face equipment. (a) On and after March 30, 1971, in mines operated entirely...

  8. 30 CFR 75.501-2 - Permissible electric face equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Permissible electric face equipment. 75.501-2... SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.501-2 Permissible electric face equipment. (a) On and after March 30, 1971, in mines operated entirely...

  9. 30 CFR 75.501-2 - Permissible electric face equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Permissible electric face equipment. 75.501-2... SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Electrical Equipment-General § 75.501-2 Permissible electric face equipment. (a) On and after March 30, 1971, in mines operated entirely...

  10. Performances of Four Helicobacter pylori Serological Detection Kits Using Stool Antigen Test as Gold Standard.

    PubMed

    Biranjia-Hurdoyal, Susheela D; Seetulsingh-Goorah, Sharmila P

    2016-01-01

    The aim was to determine the performances of four Helicobacter pylori serological detection kits in different target groups, using Amplified IDEIA™ Hp StAR™ as gold standard. Kits studied were Rapid Immunochromatoghraphic Hexagon, Helicoblot 2.1, an EIA IgG kit and EIA IgA kit. Stool and blood samples were collected from 162 apparently healthy participants (control) and 60 Type 2 diabetes mellitus (T2DM) patients. The performances of the four serological detection kits were found to be affected by gender, age, health status and ethnicity of the participants. In the control group, the Helicoblot 2.1 kit had the best performance (AUC = 0.85; p<0.05, accuracy = 86.4%), followed by EIA IgG (AUC = 0.75; p<0.05, accuracy = 75.2%). The Rapid Hexagon and EIA IgA kits had relatively poor performances. In the T2DM subgroup, the kits H2.1 and EIA IgG had best performances, with accuracies of 96.5% and 93.1% respectively. The performance of EIA IgG improved with adjustment of its cut-off value. The performances of the detection kits were affected by various factors which should be taken into consideration.

  11. Office of Space Flight standard spaceborne Global Positioning System user equipment project

    NASA Technical Reports Server (NTRS)

    Saunders, Penny E.

    1991-01-01

    The Global Positioning System (GPS) provides users autonomous, real-time navigation capability. A vehicle equipped with GPS user equipment can receive and process signals transmitted by a constellation of GPS satellites and derive from the resulting measurements the vehicle's position and velocity. Specified accuracies range from 16 to 76 meters and 0.1 to 1.0 meters/second for position and velocity, respectively. In a rendezvous and docking scenario, the use of a technique called relative GPS can provide range and range rate accuracies on the order of 1 meter and 0.01 meters/second, respectively. Relative GPS requires both vehicles to be equipped with GPS user equipment and a data communication link for transmission of GPS data and GPS satellite selection coordination information. Through coordinated satellite selection, GPS measurement errors common to both users are cancelled and improved relative position and velocity accuracies are achieved. The background, the design approach, the expected performance and capabilities, the development plan, and the project status are described. In addition, a description of relative GPS, the possible GPS hardware and software configurations, and its application to automated rendezvous and capture are presented.

  12. A new gold standard approach to characterize the transport of Si across cell membranes in animals.

    PubMed

    Garneau, Alexandre P; Marcoux, Andrée-Anne; Frenette-Cotton, Rachelle; Bélanger, Richard; Isenring, Paul

    2018-01-11

    Silicon (Si) is increasingly recognized as an essential trace element in animals, especially since the identification of mammalian Si transport systems and Si responsive genes not long ago. During many years, however, efforts to gain substantial insight into the biological role of this element in animals have achieved partial success due in part to the unavailability of validated protocols to study Si movement across biological membranes. To circumvent such limitations, we have developed a general transport assay in which cellular Si content was determined by automated electrothermal atomic absorption spectrophotometry. We have found this assay to provide great analytic sensitivity with Si detection thresholds of less than 1 µM, that is, below or very close to the concentration range of animal cells. We have also found this assay to provide valid and cost-effective determinations in Si transport studies while requiring workable quantities of samples. The protocol described here should thus become gold standard toward accelerated progress in the field of Si transport. © 2018 Wiley Periodicals, Inc.

  13. Gold Leaching Characteristics and Intensification of a High S and As-Bearing Gold Concentrate

    NASA Astrophysics Data System (ADS)

    Yang, Yong-bin; Liu, Xiao-liang; Jiang, Tao; Li, Qian; Xu, Bin; Zhang, Yan

    Some high sulfur and arsenic-bearing gold concentrate has a gold leaching rate less than 80% by oxidation roasting-pickling-cyanidation process. The characteristics and intensification of gold leaching were studied systemically. By combining chemical composition and phase analysis, the low gold leaching rate was found to lie in the capsulation of gold by iron-containing phases including iron oxides, arsenopyrite and pyrite. 96.66% of gold in the industrial leaching residue was capsulated and 95.88% of the capsulated turned out to be in the iron-containing phases. The results of laboratory pickling-cyanidation experiments on the calcine and industrial leaching residue presented further demonstration for the fact that gold capsulated in the iron-containing phases was hard to be leached. However, the gold cyanide leaching rate of calcine could be raised over 95% by a reduction roasting-pickling pretreatment which played such a significant role in exposing the capsulated gold that gold leaching was intensified remarkably.

  14. Gold internal standard correction for elemental imaging of soft tissue sections by LA-ICP-MS: element distribution in eye microstructures.

    PubMed

    Konz, Ioana; Fernández, Beatriz; Fernández, M Luisa; Pereiro, Rosario; González, Héctor; Alvarez, Lydia; Coca-Prados, Miguel; Sanz-Medel, Alfredo

    2013-04-01

    Laser ablation coupled to inductively coupled plasma mass spectrometry has been developed for the elemental imaging of Mg, Fe and Cu distribution in histological tissue sections of fixed eyes, embedded in paraffin, from human donors (cadavers). This work presents the development of a novel internal standard correction methodology based on the deposition of a homogeneous thin gold film on the tissue surface and the use of the (197)Au(+) signal as internal standard. Sample preparation (tissue section thickness) and laser conditions were carefully optimized, and internal normalisation using (197)Au(+) was compared with (13)C(+) correction for imaging applications. (24)Mg(+), (56)Fe(+) and (63)Cu(+) distributions were investigated in histological sections of the anterior segment of the eye (including the iris, ciliary body, cornea and trabecular meshwork) and were shown to be heterogeneously distributed along those tissue structures. Reproducibility was assessed by imaging different human eye sections from the same donor and from ten different eyes from adult normal donors, which showed that similar spatial maps were obtained and therefore demonstrate the analytical potential of using (197)Au(+) as internal standard. The proposed analytical approach could offer a robust tool with great practical interest for clinical studies, e.g. to investigate trace element distribution of metals and their alterations in ocular diseases.

  15. The covalent interaction between dihydrogen and gold: A rotational spectroscopic study of H2-AuCl

    NASA Astrophysics Data System (ADS)

    Obenchain, Daniel A.; Frank, Derek S.; Grubbs, G. S.; Pickett, Herbert M.; Novick, Stewart E.

    2017-05-01

    The pure rotational transitions of H2-AuCl have been measured using a pulsed-jet cavity Fourier transform microwave spectrometer equipped with a laser ablation source. The structure was found to be T-shaped, with the H-H bond interacting with the gold atom. Both 35Cl and 37Cl isotopologues have been measured for both ortho and para states of H2. Rotational constants, quartic centrifugal distortion constants, and nuclear quadrupole coupling constants for gold and chlorine have been determined. The use of the nuclear spin-nuclear spin interaction terms Daa, Dbb, and Dcc for H2 were required to fit the ortho state of hydrogen, as well as a nuclear-spin rotation constant Caa. The values of the nuclear quadrupole coupling constant of gold are χa a=-817.9929 (35 ) MHz, χb b=504.0 (27 ) MHz, and χc c=314.0 (27 ) . This is large compared to the eQq of AuCl, 9.63 312(13) MHz, which indicates a strong, covalent interaction between gold and dihydrogen.

  16. Guidelines for Equipment To Prepare Healthy Meals.

    ERIC Educational Resources Information Center

    Nettles, Mary Frances; Carr, Deborah H.

    The National Food Service Management Institute (NFSMI) has conducted a project to develop guidelines on the type of preparation equipment needed in school kitchens to produce meals that meet the nutrition standards of the Dietary Guidelines for Americans (DGA). The guidelines provide detailed descriptions of food preparation equipment items,…

  17. Equipped for the Future Content Standards. What Adults Need To Know and Be Able To Do in the 21st Century.

    ERIC Educational Resources Information Center

    Stein, Sondra

    This document presents the Equipped for the Future Framework (EFF) content standards that were developed over a 6-year period by hundreds of adult education practitioners, experts, and others nationwide to create a working consensus on what adults need to know and be able to do in the 21st century. Chapter 1 defines adult literacy for the 21st…

  18. 40 CFR 273.4 - Applicability-Mercury-containing equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... equipment. 273.4 Section 273.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR UNIVERSAL WASTE MANAGEMENT General § 273.4 Applicability—Mercury...-containing components have been removed. (c) Generation of waste mercury-containing equipment. (1) Used...

  19. Prehospital Emergencies in Illegal Gold Mining Sites in French Guiana.

    PubMed

    Egmann, Gérald; Tattevin, Pierre; Palancade, Renaud; Nacher, Matthieu

    2018-03-01

    Illegal gold mining is flourishing in French Guiana, existing outside the law due to both the high cost of gold mining permits and the challenges of law enforcement within the Amazon forest. We report the characteristics of, and the medical responses to, medical emergencies in illegal gold mining sites. We performed a retrospective study of all medical emergencies reported from illegal gold mining sites to the centralized call office of SAMU 973 from 1998 through 2000 and from 2008 through 2010. According to the national health care system, any medical emergency within the territory is handled by the prehospital emergency medical service (SAMU 973), irrespective of the patients' legal status. Data were extracted from the SAMU 973 notebook registry (1998-2000) or the SAMU 973 computerized database (2008-2010) and werre collected using a standardized questionnaire. Of 71,932 calls for medical emergencies in French Guiana during the study periods, 340 (0.5%) originated from illegal gold mining sites. Of these, 196 (58%) led to medical evacuation by helicopter, whereas the overall rate of evacuation by helicopter after placing a call to SAMU 973 was only 4% (3020/71,932; P<0.0001 for comparison with illegal gold mining sites). Medical emergencies were classified as illness (48%, mostly infectious), trauma (44%, mostly weapon wounds), and miscellaneous (8%). Medical emergencies at illegal gold mining sites in the Amazon forest mostly include infectious diseases, followed by trauma, and often require medical evacuation by helicopter. Our study suggests that implementation of preventive medicine within gold mining sites, irrespective of their legal status, could be cost-effective and reduce morbidity. Copyright © 2017 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.

  20. Making and Measuring the California History Standards

    ERIC Educational Resources Information Center

    Fogo, Bradley

    2011-01-01

    The California history and social science standards-based reform has been touted as the "gold standard" for state history curricula. But the standards, framework, and tests that constitute this reform provide inconsistent and contradictory criteria for teaching and assessing history and social science. An examination of the political…