General-purpose interface bus for multiuser, multitasking computer system

NASA Technical Reports Server (NTRS)

Generazio, Edward R.; Roth, Don J.; Stang, David B.

1990-01-01

The architecture of a multiuser, multitasking, virtual-memory computer system intended for the use by a medium-size research group is described. There are three central processing units (CPU) in the configuration, each with 16 MB memory, and two 474 MB hard disks attached. CPU 1 is designed for data analysis and contains an array processor for fast-Fourier transformations. In addition, CPU 1 shares display images viewed with the image processor. CPU 2 is designed for image analysis and display. CPU 3 is designed for data acquisition and contains 8 GPIB channels and an analog-to-digital conversion input/output interface with 16 channels. Up to 9 users can access the third CPU simultaneously for data acquisition. Focus is placed on the optimization of hardware interfaces and software, facilitating instrument control, data acquisition, and processing.

Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice.

PubMed

Jansen, A J Gerard; Josefsson, Emma C; Rumjantseva, Viktoria; Liu, Qiyong Peter; Falet, Hervé; Bergmeier, Wolfgang; Cifuni, Stephen M; Sackstein, Robert; von Andrian, Ulrich H; Wagner, Denisa D; Hartwig, John H; Hoffmeister, Karin M

2012-02-02

When refrigerated platelets are rewarmed, they secrete active sialidases, including the lysosomal sialidase Neu1, and express surface Neu3 that remove sialic acid from platelet von Willebrand factor receptor (VWFR), specifically the GPIbα subunit. The recovery and circulation of refrigerated platelets is greatly improved by storage in the presence of inhibitors of sialidases. Desialylated VWFR is also a target for metalloproteinases (MPs), because GPIbα and GPV are cleaved from the surface of refrigerated platelets. Receptor shedding is inhibited by the MP inhibitor GM6001 and does not occur in Adam17(ΔZn/ΔZn) platelets expressing inactive ADAM17. Critically, desialylation in the absence of MP-mediated receptor shedding is sufficient to cause the rapid clearance of platelets from circulation. Desialylation of platelet VWFR therefore triggers platelet clearance and primes GPIbα and GPV for MP-dependent cleavage.

Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice

PubMed Central

Jansen, A. J. Gerard; Josefsson, Emma C.; Rumjantseva, Viktoria; Liu, Qiyong Peter; Falet, Hervé; Bergmeier, Wolfgang; Cifuni, Stephen M.; Sackstein, Robert; von Andrian, Ulrich H.; Wagner, Denisa D.; Hartwig, John H.

2012-01-01

When refrigerated platelets are rewarmed, they secrete active sialidases, including the lysosomal sialidase Neu1, and express surface Neu3 that remove sialic acid from platelet von Willebrand factor receptor (VWFR), specifically the GPIbα subunit. The recovery and circulation of refrigerated platelets is greatly improved by storage in the presence of inhibitors of sialidases. Desialylated VWFR is also a target for metalloproteinases (MPs), because GPIbα and GPV are cleaved from the surface of refrigerated platelets. Receptor shedding is inhibited by the MP inhibitor GM6001 and does not occur in Adam17ΔZn/ΔZn platelets expressing inactive ADAM17. Critically, desialylation in the absence of MP-mediated receptor shedding is sufficient to cause the rapid clearance of platelets from circulation. Desialylation of platelet VWFR therefore triggers platelet clearance and primes GPIbα and GPV for MP-dependent cleavage. PMID:22101895

Critical role of platelet glycoprotein ibα in arterial remodeling.

PubMed

Chandraratne, Sue; von Bruehl, Marie-Luise; Pagel, Judith-Irina; Stark, Konstantin; Kleinert, Eike; Konrad, Ildiko; Farschtschi, Said; Coletti, Raffaele; Gärtner, Florian; Chillo, Omari; Legate, Kyle R; Lorenz, Michael; Rutkowski, Simon; Caballero-Martinez, Amelia; Starke, Richard; Tirniceriu, Anca; Pauleikhoff, Laurenz; Fischer, Silvia; Assmann, Gerald; Mueller-Hoecker, Josef; Ware, Jerry; Nieswandt, Bernhard; Schaper, Wolfgang; Schulz, Christian; Deindl, Elisabeth; Massberg, Steffen

2015-03-01

Arteriogenesis is strongly dependent on the recruitment of leukocytes, especially monocytes, into the perivascular space of growing collateral vessels. On the basis of previous findings that platelets are central players in inflammatory processes and mediate the recruitment of leukocytes, the aim of this study was to assess the role of platelets in a model of arterial remodeling. C57Bl6 wild-type mice, IL4-R/Iba mice lacking the extracellular domain of the glycoprotein Ibα (GPIbα) receptor, and mice treated with antibodies to block GPIbα or deplete circulating platelets were studied in peripheral arteriogenesis. Using a novel model of intravital 2-photon and epifluorescence imaging, we visualized and quantified the interaction of platelets with leukocytes and the vascular endothelium in vivo. We found that transient platelet adhesion to the endothelium of collateral vessels was a major event during arteriogenesis and depended on GPIbα. Furthermore, leukocyte recruitment was obviously affected in animals with defective platelet GPIbα function. In IL4-R/Iba mice, transient and firm leukocyte adhesion to the endothelium of collateral vessels, as well as leukocyte accumulation in the perivascular space, were significantly reduced. Furthermore, we detected platelet-leukocyte aggregates within the circulation, which were significantly reduced in IL4-R/Iba animals. Finally, platelet depletion and loss of GPIbα function resulted in poor reperfusion recovery as determined by laser Doppler imaging. Thus, GPIbα-mediated interactions between platelets and endothelial cells, as well as leukocytes, support innate immune cell recruitment and promote arteriogenesis-establishing platelets as critical players in this process. © 2014 American Heart Association, Inc.

Time-resolved laser-induced fluorescence system

NASA Astrophysics Data System (ADS)

Bautista, F. J.; De la Rosa, J.; Gallegos, F. J.

2006-02-01

Fluorescence methods are being used increasingly in the measurement of species concentrations in gases, liquids and solids. Laser induced fluorescence is spontaneous emission from atoms or molecules that have been excited by laser radiation. Here we present a time resolved fluorescence instrument that consists of a 5 μJ Nitrogen laser (337.1 nm), a sample holder, a quartz optical fiber, a spectrometer, a PMT and a PC that allows the measurement of visible fluorescence spectra (350-750 nm). Time response of the system is approximately 5 ns. The instrument has been used in the measurement of colored bond paper, antifreeze, diesel, cochineal pigment and malignant tissues. The data acquisition was achieved through computer control of a digital oscilloscope (using General Purpose Interface Bus GPIB) and the spectrometer via serial (RS232). The instrument software provides a graphic interface that lets make some data acquisition tasks like finding fluorescence spectra, and fluorescence lifetimes. The software was developed using the Lab-View 6i graphic programming package and can be easily managed in order to add more functions to it.

Comparison of platelet function and viscoelastic test results between healthy dogs and dogs with naturally occurring chronic kidney disease.

PubMed

Dudley, Alicia; Byron, Julie K; Burkhard, Mary Jo; Warry, Emma; Guillaumin, Julien

2017-05-01

OBJECTIVE To compare platelet function and viscoelastic test results between healthy dogs and dogs with chronic kidney disease (CKD) to assess whether dogs with CKD have platelet dysfunction and altered blood coagulation. ANIMALS 10 healthy control dogs and 11 dogs with naturally occurring CKD. PROCEDURES Blood and urine were collected once from each dog for a CBC, serum biochemical analysis, urinalysis, and determination of the urine protein-to-creatinine ratio, prothrombin time, activated partial thromboplastin time, plasma fibrinogen concentration, and antithrombin activity. Closure time was determined by use of a platelet function analyzer and a collagen-ADP platelet agonist. Thromboelastography (TEG) variables (reaction time, clotting time, α angle, maximum amplitude, and global clot strength [G value]) were determined by use of recalcified nonactivated TEG. Platelet expression of glycoprotein Ib (GPIb; receptor for von Willebrand factor), integrin αIIbβ3 (αIIbβ3; receptor for fibrinogen), and P-selectin (marker for platelet activation) was assessed by flow cytometry. RESULTS Compared with healthy control dogs, the median closure time was prolonged, the median maximum amplitude and G value were increased, and the median clotting time was decreased for dogs with CKD. Platelet expression of both αIIbβ3 and P-selectin was also significantly increased for dogs with CKD, compared with that for control dogs. Platelet expression of GPIb, αIIbβ3, and P-selectin was not correlated with closure time or any TEG variable. CONCLUSIONS AND CLINICAL RELEVANCE Results indicated that dogs with CKD frequently had evidence of platelet dysfunction and hypercoagulability that were not totally attributable to alterations in platelet surface expression of GPIb, αIIbβ3, and P-selectin.

Refrigeration-Induced Binding of von Willebrand Factor Facilitates Fast Clearance of Refrigerated Platelets.

PubMed

Chen, Wenchun; Druzak, Samuel A; Wang, Yingchun; Josephson, Cassandra D; Hoffmeister, Karin M; Ware, Jerry; Li, Renhao

2017-12-01

Apheresis platelets for transfusion treatment are currently stored at room temperature because after refrigeration platelets are rapidly cleared on transfusion. In this study, the role of von Willebrand factor (VWF) in the clearance of refrigerated platelets is addressed. Human and murine platelets were refrigerated in gas-permeable bags at 4°C for 24 hours. VWF binding, platelet signaling events, and platelet post-transfusion recovery and survival were measured. After refrigeration, the binding of plasma VWF to platelets was drastically increased, confirming earlier studies. The binding was blocked by peptide OS1 that bound specifically to platelet glycoprotein (GP)Ibα and was absent in VWF - / - plasma. Although surface expression of GPIbα was reduced after refrigeration, refrigeration-induced VWF binding under physiological shear induced unfolding of the GPIbα mechanosensory domain on the platelet, as evidenced by increased exposure of a linear epitope therein. Refrigeration and shear treatment also induced small elevation of intracellular Ca 2+ , phosphatidylserine exposure, and desialylation of platelets, which were absent in VWF -/- platelets or inhibited by OS1, which is a monomeric 11-residue peptide (CTERMALHNLC). Furthermore, refrigerated VWF -/- platelets displayed increased post-transfusion recovery and survival than wild-type ones. Similarly, adding OS1 to transgenic murine platelets expressing only human GPIbα during refrigeration improved their post-transfusion recovery and survival. Refrigeration-induced binding of VWF to platelets facilitates their rapid clearance by inducing GPIbα-mediated signaling. Our results suggest that inhibition of the VWF-GPIbα interaction may be a potential strategy to enable refrigeration of platelets for transfusion treatment. © 2017 American Heart Association, Inc.

Using the ATL HDI 1000 to collect demodulated RF data for monitoring HIFU lesion formation

NASA Astrophysics Data System (ADS)

Anand, Ajay; Kaczkowski, Peter J.; Daigle, Ron E.; Huang, Lingyun; Paun, Marla; Beach, Kirk W.; Crum, Lawrence A.

2003-05-01

The ability to accurately track and monitor the progress of lesion formation during HIFU (High Intensity Focused Ultrasound) therapy is important for the success of HIFU-based treatment protocols. To aid in the development of algorithms for accurately targeting and monitoring formation of HIFU induced lesions, we have developed a software system to perform RF data acquisition during HIFU therapy using a commercially available clinical ultrasound scanner (ATL HDI 1000, Philips Medical Systems, Bothell, WA). The HDI 1000 scanner functions on a software dominant architecture, permitting straightforward external control of its operation and relatively easy access to quadrature demodulated RF data. A PC running a custom developed program sends control signals to the HIFU module via GPIB and to the HDI 1000 via Telnet, alternately interleaving HIFU exposures and RF frame acquisitions. The system was tested during experiments in which HIFU lesions were created in excised animal tissue. No crosstalk between the HIFU beam and the ultrasound imager was detected, thus demonstrating synchronization. Newly developed acquisition modes allow greater user control in setting the image geometry and scanline density, and enables high frame rate acquisition. This system facilitates rapid development of signal-processing based HIFU therapy monitoring algorithms and their implementation in image-guided thermal therapy systems. In addition, the HDI 1000 system can be easily customized for use with other emerging imaging modalities that require access to the RF data such as elastographic methods and new Doppler-based imaging and tissue characterization techniques.

Flow cytometric immunobead assay for quantitative detection of platelet autoantibodies in immune thrombocytopenia patients.

PubMed

Zhai, Juping; Ding, Mengyuan; Yang, Tianjie; Zuo, Bin; Weng, Zhen; Zhao, Yunxiao; He, Jun; Wu, Qingyu; Ruan, Changgeng; He, Yang

2017-10-23

Platelet autoantibody detection is critical for immune thrombocytopenia (ITP) diagnosis and prognosis. Therefore, we aimed to establish a quantitative flow cytometric immunobead assay (FCIA) for ITP platelet autoantibodies evaluation. Capture microbeads coupled with anti-GPIX, -GPIb, -GPIIb, -GPIIIa and P-selectin antibodies were used to bind the platelet-bound autoantibodies complex generated from plasma samples of 250 ITP patients, 163 non-ITP patients and 243 healthy controls, a fluorescein isothiocyanate (FITC)-conjugated secondary antibody was the detector reagent and mean fluorescence intensity (MFI) signals were recorded by flow cytometry. Intra- and inter-assay variations of the quantitative FCIA assay were assessed. Comparisons of the specificity, sensitivity and accuracy between quantitative and qualitative FCIA or monoclonal antibody immobilization of platelet antigen (MAIPA) assay were performed. Finally, treatment process was monitored by our quantitative FCIA in 8 newly diagnosed ITPs. The coefficient of variations (CV) of the quantitative FCIA assay were respectively 9.4, 3.8, 5.4, 5.1 and 5.8% for anti-GPIX, -GPIb, -GPIIIa, -GPIIb and -P-selectin autoantibodies. Elevated levels of autoantibodies against platelet glycoproteins GPIX, GPIb, GPIIIa, GPIIb and P-selectin were detected by our quantitative FCIA in ITP patients compared to non-ITP patients or healthy controls. The sensitivity, specificity and accuracy of our quantitative assay were respectively 73.13, 81.98 and 78.65% when combining all 5 autoantibodies, while the sensitivity, specificity and accuracy of MAIPA assay were respectively 41.46, 90.41 and 72.81%. A quantitative FCIA assay was established. Reduced levels of platelet autoantibodies could be confirmed by our quantitative FCIA in ITP patients after corticosteroid treatment. Our quantitative assay is not only good for ITP diagnosis but also for ITP treatment monitoring.

Platelet glycoprotein Ibα forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF

PubMed Central

Yago, Tadayuki; Lou, Jizhong; Wu, Tao; Yang, Jun; Miner, Jonathan J.; Coburn, Leslie; López, José A.; Cruz, Miguel A.; Dong, Jing-Fei; McIntire, Larry V.; McEver, Rodger P.; Zhu, Cheng

2008-01-01

Arterial blood flow enhances glycoprotein Ibα (GPIbα) binding to vWF, which initiates platelet adhesion to injured vessels. Mutations in the vWF A1 domain that cause type 2B von Willebrand disease (vWD) reduce the flow requirement for adhesion. Here we show that increasing force on GPIbα/vWF bonds first prolonged (“catch”) and then shortened (“slip”) bond lifetimes. Two type 2B vWD A1 domain mutants, R1306Q and R1450E, converted catch bonds to slip bonds by prolonging bond lifetimes at low forces. Steered molecular dynamics simulations of GPIbα dissociating from the A1 domain suggested mechanisms for catch bonds and their conversion by the A1 domain mutations. Catch bonds caused platelets and GPIbα-coated microspheres to roll more slowly on WT vWF and WT A1 domains as flow increased from suboptimal levels, explaining flow-enhanced rolling. Longer bond lifetimes at low forces eliminated the flow requirement for rolling on R1306Q and R1450E mutant A1 domains. Flowing platelets agglutinated with microspheres bearing R1306Q or R1450E mutant A1 domains, but not WT A1 domains. Therefore, catch bonds may prevent vWF multimers from agglutinating platelets. A disintegrin and metalloproteinase with a thrombospondin type 1 motif–13 (ADAMTS-13) reduced platelet agglutination with microspheres bearing a tridomain A1A2A3 vWF fragment with the R1450E mutation in a shear-dependent manner. We conclude that in type 2B vWD, prolonged lifetimes of vWF bonds with GPIbα on circulating platelets may allow ADAMTS-13 to deplete large vWF multimers, causing bleeding. PMID:18725999

Development of a portable graphite calorimeter for radiation dosimetry.

PubMed

Sakama, Makoto; Kanai, Tatsuaki; Fukumura, Akifumi

2008-01-01

We developed and performance-tested a portable graphite calorimeter designed to measure the absolute dosimetry of various beams including heavy-ion beams, based on a flexible and convenient means of measurement. This measurement system is fully remote-controlled by the GPIB system. This system uses a digital PID (Proportional, Integral, Derivative) control method based on the LabVIEW software. It was possible to attain stable conditions in a shorter time by this system. The standard deviation of the measurements using the calorimeter was 0.79% at a dose rate of 0.8 Gy/min in 17 calorimeter runs for a (60)Co photon beam. The overall uncertainties for the absorbed dose to graphite and water of the (60)Co photon beam using the developed calorimeter were 0.89% and 1.35%, respectively. Estimations of the correction factors due to vacuum gaps, impurities in the core, the dose gradient and the radiation profile were included in the uncertainties. The absorbed doses to graphite and water irradiated by the (60)Co photon beam were compared with dosimetry measurements obtained using three ionization chambers. The absorbed doses to graphite and water estimated by the two dosimetry methods agreed within 0.1% and 0.3%, respectively.

Performance evaluation and multicentre study of a von Willebrand factor activity assay based on GPIb binding in the absence of ristocetin.

PubMed

Patzke, Juergen; Budde, Ulrich; Huber, Andreas; Méndez, Adriana; Muth, Heidrun; Obser, Tobias; Peerschke, Ellinor; Wilkens, Matthias; Schneppenheim, Reinhard

2014-12-01

The functional activity of von Willebrand factor (VWF) is most frequently measured by using the ristocetin cofactor assay (VWF:RCo). However, the method's drawbacks include unsatisfactory precision, sensitivity and availability of automated system applications. We have developed an alternative assay (INNOVANCE VWF Ac) that is based on the binding of VWF to recombinant glycoprotein Ib (GPIb). Two gain-of-function mutations were introduced into a GPIb fragment, allowing an assay format without ristocetin. Fully automated assay applications are available for the BCS/BCS XP systems and the Sysmex CS-2000i, Sysmex CA-7000, Sysmex CA-1500 and Sysmex CA-560 systems.The INNOVANCE VWF Ac assay measuring range extends from 4 to 600% VWF for all systems except the Sysmex CA-560 system. Within-device precision values were found to be between 2 and 7%. The limit of detection was below 2.2% VWF. In a study on the BCS XP system, a total number of 580 sample results yielded a correlation to the VWF:RCo assay of r equal to 0.99 (slope = 0.96). Very similar results were observed when von Willebrand disease samples type 1, 2A, 2B, 2M, 2N and 3 were investigated with the new assay and the VWF:RCo assay. The excellent performance data and comparability to VWF:RCo, together with the ease of use, led us to the conclusion that the ristocetin cofactor assay can be replaced by the new GPIb-binding assay to reliably diagnosing patients with von Willebrand disease.

High shear induces platelet dysfunction leading to enhanced thrombotic propensity and diminished hemostatic capacity.

PubMed

Chen, Zengsheng; Mondal, Nandan K; Zheng, Shirong; Koenig, Steven C; Slaughter, Mark S; Griffith, Bartley P; Wu, Zhongjun J

2017-11-28

Thrombosis and bleeding are devastating adverse events in patients supported with blood-contacting medical devices (BCMDs). In this study, we delineated that high non-physiological shear stress (NPSS) caused platelet dysfunction that may contribute to both thrombosis and bleeding. Human blood was subjected to NPSS with short exposure time. Levels of platelet surface GPIbα and GPVI receptors as well as activation level of GPIIb/IIIa in NPSS-sheared blood were examined with flow cytometry. Adhesion of sheared platelets on fibrinogen, von Willibrand factor (VWF), and collagen was quantified with fluorescent microscopy. Ristocetin- and collagen-induced platelet aggregation was characterized by aggregometry. NPSS activated platelets in a shear and exposure time-dependent manner. The number of activated platelets increased with increasing levels of NPSS and exposure time, which corresponded well with increased adhesion of sheared platelets on fibrinogen. Concurrently, NPSS caused shedding of GPIbα and GPVI in a manner dependent on shear and exposure time. The loss of intact GPIbα and GPVI increased with increasing levels of NPSS and exposure time. The number of platelets adhered on VWF and collagen decreased with increasing levels of NPSS and exposure time, respectively. The decrease in the number of platelets adhered on VWF and collagen corresponded well with the loss in GPIbα and GPVI on platelet surface. Both ristocetin- and collagen-induced platelet aggregation in sheared blood decreased with increasing levels of NPSS and exposure time. The study clearly demonstrated that high NPSS causes simultaneous platelet activation and receptor shedding, resulting in a paradoxical effect on platelet function via two distinct mechanisms. The results from the study suggested that the NPSS could induce the concurrent propensity for both thrombosis and bleeding in patients.

Alloimmunization in Congenital Deficiencies of Platelet Surface Glycoproteins: Focus on Glanzmann's Thrombasthenia and Bernard-Soulier's Syndrome.

PubMed

Poon, Man-Chiu; d'Oiron, Roseline

2018-06-07

Glanzmann's thrombasthenia (GT) and Bernard-Soulier's syndrome (BSS) are well-understood congenital bleeding disorders, showing defect/deficiency of platelet glycoprotein (GP) IIb/IIIa (integrin αIIbβ3) and GPIb-IX-V complexes respectively, with relevant clinical, laboratory, biochemical, and genetic features. Following platelet transfusion, affected patients may develop antiplatelet antibodies (to human leukocyte antigen [HLA], and/or αIIbβ3 in GT or GPIb-IX in BSS), which may render future platelet transfusion ineffective. Anti-αIIbβ3 and anti-GPIb-IX may also cross the placenta during pregnancy to cause thrombocytopenia and bleeding in the fetus/neonate. This review will focus particularly on the better studied GT to illustrate the natural history and complications of platelet alloimmunization. BSS will be more briefly discussed. Platelet transfusion, if unavoidable, should be given judiciously with good indications. Patients following platelet transfusion, and women during and after pregnancy, should be monitored for the development of platelet antibodies. There is now a collection of data suggesting the safety and effectiveness of recombinant activated factor VII in the management of affected patients with platelet antibodies. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Mutant botrocetin-2 inhibits von Willebrand factor-induced platelet agglutination.

PubMed

Matsui, T; Hori, A; Hamako, J; Matsushita, F; Ozeki, Y; Sakurai, Y; Hayakawa, M; Matsumoto, M; Fujimura, Y

2017-03-01

Essentials Botrocetin-2 (Bot2) binds to von Willebrand factor (VWF) and induces platelet agglutination. We identified Bot2 residues that are required for binding to VWF and glycoprotein (GP) Ib. We produced a mutant Bot2 that binds to VWF but inhibits platelet agglutination. Mutant Bot2 could be used as a potential anti-thrombotic reagent to block VWF-GPIb interaction. Background Botrocetin-2 (Bot2) is a botrocetin-like protein composed of α and β subunits that have been cloned from the snake Bothrops jararaca. Bot2 binds specifically to von Willebrand factor (VWF), and the complex induces glycoprotein (GP) Ib-dependent platelet agglutination. Objectives To exploit Bot2's VWF-binding capacity in order to attempt to create a mutant Bot2 that binds to VWF but inhibits platelet agglutination. Methods and Results Several point mutations were introduced into Bot2 cDNA, and the recombinant protein (recombinant Bot2 [rBot2]) was purified on an anti-botrocetin column. The mutant rBot2 with either Ala at Asp70 in the β subunit (Aspβ70Ala), or Argβ115Ala and Lysβ117Ala, showed reduced platelet agglutination-inducing activity. rBot2 with Aspβ70Ala showed little binding activity towards immobilized VWF on an ELISA plate, whereas rBot2 with Argβ115Ala/Lysβ117Ala showed reduced binding activity towards GPIb (glycocalicin) after forming a complex with VWF. rBot2 point-mutated to oppositely charged Glu at both Argβ115 and Lysβ117 showed normal binding activity towards VWF but no platelet-agglutinating activity. Furthermore, this doubly mutated protein inhibited ristocetin-induced or high shear stress-induced platelet aggregation, and restrained thrombus formation under flow conditions. Conclusions Asp70 in the β subunit of botrocetin is important for VWF binding, and Arg115 and Lys117 in the β subunit are essential for interaction with GPIb. Doubly mutated rBot2, with Argβ115Glu and Lysβ117Glu, repels GPIb and might have potential as an antithrombotic reagent that specifically blocks VWF function. This is the first report on an artificial botrocetin that can inhibit the VWF-GPIb interaction. © 2017 International Society on Thrombosis and Haemostasis.

Selective Inhibition of ADAM17 Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell‐Derived Platelets

PubMed Central

Hirata, Shinji; Murata, Takahiko; Suzuki, Daisuke; Nakamura, Sou; Jono‐Ohnishi, Ryoko; Hirose, Hidenori; Sawaguchi, Akira; Nishimura, Satoshi; Sugimoto, Naoshi

2016-01-01

Abstract Donor‐independent platelet concentrates for transfusion can be produced in vitro from induced pluripotent stem cells (iPSCs). However, culture at 37°C induces ectodomain shedding on platelets of glycoprotein Ibα (GPIbα), the von Willebrand factor receptor critical for adhesive function and platelet lifetime in vivo, through temperature‐dependent activation of a disintegrin and metalloproteinase 17 (ADAM17). The shedding can be suppressed by using inhibitors of panmetalloproteinases and possibly of the upstream regulator p38 mitogen‐activated protein kinase (p38 MAPK), but residues of these inhibitors in the final platelet products may be accompanied by harmful risks that prevent clinical application. Here, we optimized the culture conditions for generating human iPSC‐derived GPIbα+ platelets, focusing on culture temperature and additives, by comparing a new and safe selective ADAM17 inhibitor, KP‐457, with previous inhibitors. Because cultivation at 24°C (at which conventional platelet concentrates are stored) markedly diminished the yield of platelets with high expression of platelet receptors, 37°C was requisite for normal platelet production from iPSCs. KP‐457 blocked GPIbα shedding from iPSC platelets at a lower half‐maximal inhibitory concentration than panmetalloproteinase inhibitor GM‐6001, whereas p38 MAPK inhibitors did not. iPSC platelets generated in the presence of KP‐457 exhibited improved GPIbα‐dependent aggregation not inferior to human fresh platelets. A thrombus formation model using immunodeficient mice after platelet transfusion revealed that iPSC platelets generated with KP‐457 exerted better hemostatic function in vivo. Our findings suggest that KP‐457, unlike GM‐6001 or p38 MAPK inhibitors, effectively enhances the production of functional human iPSC‐derived platelets at 37°C, which is an important step toward their clinical application. Stem Cells Translational Medicine 2017;6:720–730 PMID:28297575

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wackerbarth, David

Sandia National Laboratories has developed a computer program to review, reduce and manipulate waveform data. PlotData is designed for post-acquisition waveform data analysis. PlotData is both a post-acquisition and an advanced interactive data analysis environment. PlotData requires unidirectional waveform data with both uniform and discrete time-series measurements. PlotData operates on a National Instruments' LabVIEW™ software platform. Using PlotData, the user can capture waveform data from digitizing oscilloscopes over a GPIB, USB and Ethernet interface from Tektronix, Lecroy or Agilent scopes. PlotData can both import and export several types of binary waveform files including, but not limited to, Tektronix .wmf files,more » Lecroy.trc files and xy pair ASCIIfiles. Waveform manipulation includes numerous math functions, integration, differentiation, smoothing, truncation, and other specialized data reduction routines such as VISAR, POV, PVDF (Bauer) piezoelectric gauges, and piezoresistive gauges such as carbon manganin pressure gauges.« less

Olive Oil-Based Lipid Emulsions Do Not Influence Platelet Receptor Expression in Comparison to Medium and Long Chain Triglycerides In vitro.

PubMed

Stoetzer, Carsten; Nickel, Katja; Weißig, Annette; Großheim, Marieke; Scheinichen, Dirk; Doll, Thorben; Jüttner, Björn

2016-11-01

Lipid emulsions influence platelet aggregation and receptor expression. However, the effect on platelet function is not fully explained. Therefore, the aim of this study was to examine the influence of the lipids Lipofundin ® , Lipidem ® and ClinOleic ® on surface expressions of P-selectin, GPIb and GPIIb/IIIa on platelets in vitro. Whole blood was incubated in two different concentrations (0.06 and 0.6 mg/ml) of LCT/MCT, n-3/LCT/MCT and LCT-MUFA for 30 min, followed by activation with TRAP-6 or ADP for flow-cytometric assay. Rates of P-selectin, GPIb and GPIIb/IIIa expression were analyzed. There was a significant increase in GPIIb/IIIa- and P-selectin-expression after incubation with LCT/MCT and n-3/LCT/MCT at the concentration of 0.6 mg/ml, without and after stimulation with TRAP-6 and ADP. GPIb was significantly decreased. Accordingly, LCT-MUFA had no effect on receptor expression of platelets in vitro. We demonstrated that LCT-MUFA did not activate receptor expression of platelets whereas LCT/MCT significantly increased platelet aggregation in vitro. This finding should be noted for parenteral nutrition of intensive care patients and, in the future, might provide further insight into the pathogenic pathways of acute thromboembolic events. However, prospectively designed clinical studies are needed to support our results.

Computer Controlled Magnetotransport Setup for the Characterization of Semiconductor Thin Films

NASA Technical Reports Server (NTRS)

Ducoudray, G. O.; Collazo, R.; Martinez, A.

1997-01-01

We have considered a computer controlled magnetotransport setup using LabWindows environment. It allows for measurements of resistivity, Hall resistance, carrier concentration and charge mobility in semiconductor thin films using a van der Pauw configuration. The setup features an electromagnet (B = 0.7 Tesla) a 80486-DX 33 computer with a National Instrument AT-MIO 16 AD/DA and a GPIB interface board. A Keithely 224 current source and a Keithley 196 digital voltmeter were also used in the setup. Plans for the addition of capabilities to allow for magnetic field sweeping and the performance of measurements as a function of temperature will be presented.

An Optical Fiber Viscometer Based on Long-Period Fiber Grating Technology and Capillary Tube Mechanism

PubMed Central

Wang, Jian-Neng; Tang, Jaw-Luen

2010-01-01

This work addresses the development and assessment of a fiber optical viscometer using a simple and low-cost long-period fiber grating (LPFG) level sensor and a capillary tube mechanism. Previous studies of optical viscosity sensors were conducted by using different optical sensing methods. The proposed optical viscometer consists of an LPFG sensor, a temperature-controlled chamber, and a cone-shaped reservoir where gravitational force could cause fluid to flow through the capillary tube. We focused on the use of LPFGs as level sensors and the wavelength shifts were not used to quantify the viscosity values of asphalt binders. When the LPFG sensor was immersed in the constant volume (100 mL) AC-20 asphalt binder, a wavelength shift was observed and acquired using LabVIEW software and GPIB controller. The time spent between empty and 100 mL was calculated to determine the discharge time. We simultaneously measured the LPFG-induced discharge time and the transmission spectra both in hot air and AC-20 asphalt binder at five different temperatures, 60, 80, 100, 135, and 170 Celsius. An electromechanical rotational viscometer was also used to measure the viscosities, 0.15–213.80 Pa·s, of the same asphalt binder at the above five temperatures. A non-linear regression analysis was performed to convert LPFG-induced discharge time into viscosities. Comparative analysis shows that the LPFG-induced discharge time agreed well with the viscosities obtained from the rotational viscometer. PMID:22163519

ANALOG I/O MODULE TEST SYSTEM BASED ON EPICS CA PROTOCOL AND ACTIVEX CA INTERFACE

DOE Office of Scientific and Technical Information (OSTI.GOV)

YENG,YHOFF,L.

2003-10-13

Analog input (ADC) and output (DAC) modules play a substantial role in device level control of accelerator and large experiment physics control system. In order to get the best performance some features of analog modules including linearity, accuracy, crosstalk, thermal drift and so on have to be evaluated during the preliminary design phase. Gain and offset error calibration and thermal drift compensation (if needed) may have to be done in the implementation phase as well. A natural technique for performing these tasks is to interface the analog VO modules and GPIB interface programmable test instruments with a computer, which canmore » complete measurements or calibration automatically. A difficulty is that drivers of analog modules and test instruments usually work on totally different platforms (vxworks VS Windows). Developing new test routines and drivers for testing instruments under VxWorks (or any other RTOS) platform is not a good solution because such systems have relatively poor user interface and developing such software requires substantial effort. EPICS CA protocol and ActiveX CA interface provide another choice, a PC and LabVIEW based test system. Analog 110 module can be interfaced from LabVIEW test routines via ActiveX CA interface. Test instruments can be controlled via LabVIEW drivers, most of which are provided by instrument vendors or by National Instruments. Labview also provides extensive data analysis and process functions. Using these functions, users can generate powerful test routines very easily. Several applications built for Spallation Neutron Source (SNS) Beam Loss Monitor (BLM) system are described in this paper.« less

Mutational Constraints on Local Unfolding Inhibit the Rheological Adaptation of von Willebrand Factor

DOE PAGES

Tischer, Alexander; Campbell, James C.; Machha, Venkata R.; ...

2015-12-16

Unusually large von Willebrand factor (VWF), the first responder to vascular injury in primary hemostasis, is designed to capture platelets under the high shear stress of rheological blood flow. In type 2M von Willebrand disease, two rare mutations (G1324A and G1324S) within the platelet GPIbα binding interface of the VWF A1 domain impair the hemostatic function of VWF. We investigate structural and conformational effects of these mutations on the A1 domain's efficacy to bind collagen and adhere platelets under shear flow. These mutations enhance the thermodynamic stability, reduce the rate of unfolding, and enhance the A1 domain's resistance to limitedmore » proteolysis. Collagen binding affinity is not significantly affected indicating that the primary stabilizing effect of these mutations is to diminish the platelet binding efficiency under shear flow. The better stability stems from the steric consequences of adding a side chain (G1324A) and additionally a hydrogen bond (G1324S) to His 1322 across the β2-β3 hairpin in the GPIbα binding interface, which restrains the conformational degrees of freedom and the overall flexibility of the native state. These studies reveal a novel rheological strategy in which the incorporation of a single glycine within the GPIbα binding interface of normal VWF enhances the probability of local unfolding that enables the A1 domain to conformationally adapt to shear flow while maintaining its overall native structure.« less

Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearance.

PubMed

Wong, Connie H Y; Jenne, Craig N; Petri, Björn; Chrobok, Navina L; Kubes, Paul

2013-08-01

Through the use of intravital imaging of the liver, we demonstrate a collaborative role for platelets with Kupffer cells (KCs) in eradicating blood-borne bacterial infection. Under basal conditions, platelets, via the platelet-adhesion receptor GPIb, formed transient 'touch-and-go' interactions with von Willebrand factor (vWF) constitutively expressed on KCs. Bacteria such as Bacillus cereus and methicillin-resistant Staphylococcus aureus (MRSA) were rapidly caught by KCs and triggered platelets to switch from 'touch-and-go' adhesion to sustained GPIIb-mediated adhesion on the KC surface to encase the bacterium. Infected GPIbα-deficient mice had more endothelial and KC damage than did their wild-type counterparts, which led to more fluid leakage, substantial polycythemia and rapid mortality. Our study identifies a previously unknown surveillance mechanism by which platelets survey macrophages that rapidly converts to a critical host response to blood-borne bacteria.

Of von Willebrand factor and platelets.

PubMed

Bryckaert, Marijke; Rosa, Jean-Philippe; Denis, Cécile V; Lenting, Peter J

2015-01-01

Hemostasis and pathological thrombus formation are dynamic processes that require multiple adhesive receptor-ligand interactions, with blood platelets at the heart of such events. Many studies have contributed to shed light on the importance of von Willebrand factor (VWF) interaction with its platelet receptors, glycoprotein (GP) Ib-IX-V and αIIbβ3 integrin, in promoting primary platelet adhesion and aggregation following vessel injury. This review will recapitulate our current knowledge on the subject from the rheological aspect to the spatio-temporal development of thrombus formation. We will also discuss the signaling events generated by VWF/GPIb-IX-V interaction, leading to platelet activation. Additionally, we will review the growing body of evidence gathered from the recent development of pathological mouse models suggesting that VWF binding to GPIb-IX-V is a promising target in arterial and venous pathological thrombosis. Finally, the pathological aspects of VWF and its impact on platelets will be addressed.

Technological advances in diagnostic testing for von Willebrand disease: new approaches and challenges.

PubMed

Hayward, C P M; Moffat, K A; Graf, L

2014-06-01

Diagnostic tests for von Willebrand disease (VWD) are important for the assessment of VWD, which is a commonly encountered bleeding disorder worldwide. Technical innovations have been applied to improve the precision and lower limit of detection of von Willebrand factor (VWF) assays, including the ristocetin cofactor activity assay (VWF:RCo) that uses the antibiotic ristocetin to induce plasma VWF binding to glycoprotein (GP) IbIXV on target platelets. VWF-collagen-binding assays, depending on the type of collagen used, can improve the detection of forms of VWD with high molecular weight VWF multimer loss, although the best method is debatable. A number of innovations have been applied to VWF:RCo (which is commonly performed on an aggregometer), including replacing the target platelets with immobilized GPIbα, and quantification by an enzyme-linked immunosorbent assay (ELISA), immunoturbidimetric, or chemiluminescent end-point. Some common polymorphisms in the VWF gene that do not cause bleeding are associated with falsely low VWF activity by ristocetin-dependent methods. To overcome the need for ristocetin, some new VWF activity assays use gain-of-function GPIbα mutants that bind VWF without the need for ristocetin, with an improved precision and lower limit of detection than measuring VWF:RCo by aggregometry. ELISA of VWF binding to mutated GPIbα shows promise as a method to identify gain-of-function defects from type 2B VWD. The performance characteristics of many new VWF activity assays suggest that the detection of VWD, and monitoring of VWD therapy, by clinical laboratories could be improved through adopting newer generation VWF assays. © 2014 John Wiley & Sons Ltd.

Thioredoxin Inhibitors Attenuate Platelet Function and Thrombus Formation

PubMed Central

Metcalfe, Clive; Ramasubramoni, Anjana; Pula, Giordano; Harper, Matthew T.; Mundell, Stuart J.; Coxon, Carmen H.

2016-01-01

Thioredoxin (Trx) is an oxidoreductase with important physiological function. Imbalances in the NADPH/thioredoxin reductase/thioredoxin system are associated with a number of pathologies, particularly cancer, and a number of clinical trials for thioredoxin and thioredoxin reductase inhibitors have been carried out or are underway. Due to the emerging role and importance of oxidoreductases for haemostasis and the current interest in developing inhibitors for clinical use, we thought it pertinent to assess whether inhibition of the NADPH/thioredoxin reductase/thioredoxin system affects platelet function and thrombosis. We used small molecule inhibitors of Trx (PMX 464 and PX-12) to determine whether Trx activity influences platelet function, as well as an unbiased proteomics approach to identify potential Trx substrates on the surface of platelets that might contribute to platelet reactivity and function. Using LC-MS/MS we found that PMX 464 and PX-12 affected the oxidation state of thiols in a number of cell surface proteins. Key surface receptors for platelet adhesion and activation were affected, including the collagen receptor GPVI and the von Willebrand factor receptor, GPIb. To experimentally validate these findings we assessed platelet function in the presence of PMX 464, PX-12, and rutin (a selective inhibitor of the related protein disulphide isomerase). In agreement with the proteomics data, small molecule inhibitors of thioredoxin selectively inhibited GPVI-mediated platelet activation, and attenuated ristocetin-induced GPIb-vWF-mediated platelet agglutination, thus validating the findings of the proteomics study. These data reveal a novel role for thioredoxin in regulating platelet reactivity via proteins required for early platelet responses at sites of vessel injury (GPVI and GPIb). This work also highlights a potential opportunity for repurposing of PMX 464 and PX-12 as antiplatelet agents. PMID:27716777

Glycoprotein Ibα receptor instability is associated with loss of quality in platelets produced in culture.

PubMed

Robert, Amélie; Boyer, Lucie; Pineault, Nicolas

2011-03-01

The development of culture processes for hematopoietic progenitors could lead to the development of a complementary source of platelets for therapeutic purposes. However, functional characterization of culture-derived platelets remains limited, which raises some uncertainties about the quality of platelets produced in vitro. The aim of this study was to define the proportion of functional platelets produced in cord blood CD34+ cell cultures. Toward this, the morphological and functional properties of culture-derived platelet-like particles (PLPs) were critically compared to that of blood platelets. Flow cytometry combined with transmission electron microscopy analyses revealed that PLPs formed a more heterogeneous population of platelets at a different stage of maturation than blood platelets. The majority of PLPs harbored the fibrinogen receptor αIIbβ3, but a significant proportion failed to maintain glycoprotein (GP)Ibα surface expression, a component of the vWF receptor essential for platelet functions. Importantly, GPIbα extracellular expression correlated closely with platelet function, as the GPIIb+ GPIbα+ PLP subfraction responded normally to agonist stimulation as evidenced by α-granule release, adhesion, spreading, and aggregation. In contrast, the GPIIb+ GPIbα⁻ subfraction was unresponsive in most functional assays and appeared to be metabolically inactive. The present study confirms that functional platelets can be generated in cord blood CD34+ cell cultures, though these are highly susceptible to ectodomain shedding of receptors associated with loss of function. Optimization of culture conditions to prevent these deleterious effects and to homogenize PLPs is necessary to improve the quality and yields of culture-derived platelets before they can be recognized as a suitable complementary source for therapeutic purposes.

Thioredoxin Inhibitors Attenuate Platelet Function and Thrombus Formation.

PubMed

Metcalfe, Clive; Ramasubramoni, Anjana; Pula, Giordano; Harper, Matthew T; Mundell, Stuart J; Coxon, Carmen H

2016-01-01

Thioredoxin (Trx) is an oxidoreductase with important physiological function. Imbalances in the NADPH/thioredoxin reductase/thioredoxin system are associated with a number of pathologies, particularly cancer, and a number of clinical trials for thioredoxin and thioredoxin reductase inhibitors have been carried out or are underway. Due to the emerging role and importance of oxidoreductases for haemostasis and the current interest in developing inhibitors for clinical use, we thought it pertinent to assess whether inhibition of the NADPH/thioredoxin reductase/thioredoxin system affects platelet function and thrombosis. We used small molecule inhibitors of Trx (PMX 464 and PX-12) to determine whether Trx activity influences platelet function, as well as an unbiased proteomics approach to identify potential Trx substrates on the surface of platelets that might contribute to platelet reactivity and function. Using LC-MS/MS we found that PMX 464 and PX-12 affected the oxidation state of thiols in a number of cell surface proteins. Key surface receptors for platelet adhesion and activation were affected, including the collagen receptor GPVI and the von Willebrand factor receptor, GPIb. To experimentally validate these findings we assessed platelet function in the presence of PMX 464, PX-12, and rutin (a selective inhibitor of the related protein disulphide isomerase). In agreement with the proteomics data, small molecule inhibitors of thioredoxin selectively inhibited GPVI-mediated platelet activation, and attenuated ristocetin-induced GPIb-vWF-mediated platelet agglutination, thus validating the findings of the proteomics study. These data reveal a novel role for thioredoxin in regulating platelet reactivity via proteins required for early platelet responses at sites of vessel injury (GPVI and GPIb). This work also highlights a potential opportunity for repurposing of PMX 464 and PX-12 as antiplatelet agents.

Platelet interactions in thrombosis.

PubMed

Andrews, Robert K; Gardiner, Elizabeth E; Shen, Yang; Berndt, Michael C

2004-01-01

Patho/physiological platelet aggregate (thrombus) formation is initiated by engagement of platelet surface receptors, glycoprotein (GP)Ib-IX-V and GPVI that bind von Willebrand factor or collagen. Although beneficial in response to vascular injury by preventing blood loss (haemostasis), platelet aggregation in a sclerotic coronary artery or other diseased blood vessel (thrombosis) can cause thrombotic diseases like heart attack and stroke. At the molecular level, ligand interactions with GPIb-IX-V or GPVI trigger signalling responses, including elevation of cytosolic Ca2+, dissociation of calmodulin from their cytoplasmic domains, cytoskeletal actin-filament rearrangements, activation of src-family kinases or PI 3-kinase, and 'inside-out' activation of the integrin, alphaIIbbeta3 (GPIIb-llla), that binds von Willebrand factor or fibrinogen and mediates platelet aggregation. Furthermore, emerging evidence supports a topographical co-association of these receptors of the leucine-rich repeat family (GPIb-IX-V) and immunoglobulin superfamily (GPVI) in an adhesive cluster or 'adhesosome'. This arrangement may underlie common mechanisms of initiating thrombus formation in haemostasis or thrombotic disease.

Architecture for distributed actuation and sensing using smart piezoelectric elements

NASA Astrophysics Data System (ADS)

Etienne-Cummings, Ralph; Pourboghrat, Farzad; Maruboyina, Hari K.; Abrate, Serge; Dhali, Shirshak K.

1998-07-01

We discuss vibration control of a cantilevered plate with multiple sensors and actuators. An architecture is chosen to minimize the number of control and sensing wires required. A custom VLSI chip, integrated with the sensor/actuator elements, controls the local behavior of the plate. All the actuators are addressed in parallel; local decode logic selects which actuator is stimulated. Downloaded binary data controls the applied voltage and modulation frequency for each actuator, and High Voltage MOSFETs are used to activate them. The sensors, which are independent adjacent piezoelectric ceramic elements, can be accessed in a random or sequential manner. An A/D card and GPIB interconnected test equipment allow a PC to read the sensors' outputs and dictate the actuation procedure. A visual programming environment is used to integrate the sensors, controller and actuators. Based on the constitutive relations for the piezoelectric material, simple models for the sensors and actuators are derived. A two level hierarchical robust controller is derived for motion control and for damping of vibrations.

Solar Extreme Ultraviolet Rocket Telesope Spectrograph ** SERTS ** Detector and Electronics subsystems

NASA Astrophysics Data System (ADS)

Payne, L.; Haas, J. P.; Linard, D.; White, L.

1997-12-01

The Laboratory for Astronomy and Solar Physics at Goddard Space Flight Center uses a variety imaging sensors for its instrumentation programs. This paper describes the detector system for SERTS. The SERTS rocket telescope uses an open faceplate, single plate MCP tube as the primary detector for EUV spectra from the Sun. The optical output of this detector is fiber-optically coupled to a cooled, large format CCD. This CCD is operated using a software controlled Camera controller based upon a design used for the SOHO/CDS mission. This camera is a general purpose design, with a topology that supports multiple types of imaging devices. Multiport devices (up to 4 ports) and multiphase clocks are supportable as well as variable speed operation. Clock speeds from 100KHz to 1MHz have been used, and the topology is currently being extended to support 10MHz operation. The form factor for the camera system is based on the popular VME buss. Because the tube is an open faceplate design, the detector system has an assortment of vacuum doors and plumbing to allow operation in vacuum but provide for safe storage at normal atmosphere. Vac-ion pumps (3) are used to maintain working vacuum at all times. Marshall Space Flight Center provided the SERTS programs with HVPS units for both the vac-ion pumps and the MCP tube. The MCP tube HVPS is a direct derivative of the design used for the SXI mission for NOAA. Auxiliary equipment includes a frame buffer that works either as a multi-frame storage unit or as a photon counting accumulation unit. This unit also performs interface buffering so that the camera may appear as a piece of GPIB instrumentation.

A critical role for the regulation of Syk from agglutination to aggregation in human platelets.

PubMed

Shih, Chun-Ho; Chiang, Tin-Bin; Wang, Wen-Jeng

2014-01-10

Agglucetin, a tetrameric glycoprotein (GP) Ibα agonist from Formosan Agkistrodon acutus venom, has been characterized as an agglutination inducer in human washed platelets (WPs). In platelet-rich plasma (PRP), agglucetin dramatically elicits a biphasic response of agglutination and subsequent aggregation. For clarifying the intracellular signaling events from agglutination to aggregation in human platelets, we examined the essential signaling molecules involved through the detection of protein tyrosine phosphorylation (PTP). In WPs, an anti-GPIbα monoclonal antibody (mAb) AP1, but not a Src kinase inhibitor PP1, completely inhibited agglucetin-induced agglutination. However, PP1 but not AP1 had a potent suppression on platelet aggregation by a GPVI activator convulxin. The PTP analyses showed agglucetin alone can cause a weak pattern involving sequential phosphorylation of Lyn/Fyn, Syk, SLP-76 and phospholipase Cγ2 (PLCγ2). Furthermore, a Syk-selective kinase inhibitor, piceatannol, significantly suppressed the aggregating response in agglucetin-activated PRP. Analyzed by flow cytometry, the binding capacity of fluorophore-conjugated PAC-1, a mAb recognizing activated integrin αIIbβ3, was shown to increase in agglucetin-stimulated platelets. Again, piceatannol but not PP1 had a concentration-dependent suppression on agglucetin-induced αIIbβ3 exposure. Moreover, the formation of signalosome, including Syk, SLP-76, VAV, adhesion and degranulation promoting adapter protein (ADAP) and PLCγ2, are required for platelet aggregation in agglucetin/fibrinogen-activated platelets. In addition, GPIbα-ligation via agglucetin can substantially promote the interactions between αIIbβ3 and fibrinogen. Therefore, the signal pathway of Lyn/Fyn/Syk/SLP-76/ADAP/VAV/PLCγ2/PKC is sufficient to trigger platelet aggregation in agglucetin/fibrinogen-pretreated platelets. Importantly, Syk may function as a major regulator for the response from GPIbα-initiated agglutination to integrin αIIbβ3-dependent aggregation in human platelets. Copyright © 2013 Elsevier Inc. All rights reserved.

Delineating the roles of the GPIIb/IIIa and GP-Ib-IX-V platelet receptors in mediating platelet adhesion to adsorbed fibrinogen and albumin.

PubMed

Sivaraman, Balakrishnan; Latour, Robert A

2011-08-01

Platelet adhesion to adsorbed plasma proteins, such as fibrinogen (Fg), has been conventionally thought to be mediated by the GPIIb/IIIa receptor binding to Arg-Gly-Asp (RGD)-like motifs in the adsorbed protein. In previous studies, we showed that platelet adhesion response to adsorbed Fg and Alb was strongly influenced by the degree of adsorption-induced protein unfolding and that platelet adhesion was only partially blocked by soluble RGD, with RGD-blocked platelets adhering without activation. Based on these results, we hypothesized that in addition to the RGD-specific GPIIb/IIIa receptor, which mediates both adhesion and activation, a non-RGD-specific receptor set likely also plays a role in platelet adhesion (but not activation) to both Fg and albumin (Alb). To identify and elucidate the role of these receptors, in addition to GPIIb/IIIa, we also examined the GPIb-IX-V receptor complex, which has been shown to mediate platelet adhesion (but not activation) in studies by other groups. The platelet suspension was pretreated with either a GPIIb/IIIa-antagonist drug Aggrastat(®) or monoclonal antibodies 6B4 or 24G10 against GPIb-IX-V prior to adhesion on Fg- and Alb-coated OH- and CH(3)-functionalized alkanethiol self-assembled monolayer surfaces. The results revealed that GPIIb/IIIa is the primary receptor set involved in platelet adhesion to adsorbed Fg and Alb irrespective of their degree of adsorption-induced unfolding, while the GPIb-IX-V receptor complex plays an insignificant role. Overall, these studies provide novel insights into the molecular-level mechanisms mediating platelet interactions with adsorbed plasma proteins, thereby assisting the biomaterials field develop potent strategies for inhibiting platelet-protein interactions in the design of more hemocompatible cardiovascular biomaterials and effective anti-thrombotic therapies. Copyright © 2011 Elsevier Ltd. All rights reserved.

Slow Control System for the NIFFTE Collaboration TPC

NASA Astrophysics Data System (ADS)

Ringle, Erik; Niffte Collaboration Collaboration

2011-10-01

As world energy concerns continue to dominate public policy in the 21st century, the need for cleaner and more efficient nuclear power is necessary. In order to effectively design and implement plans for generation IV nuclear reactors, more accurate fission cross-section measurements are necessary. The Neutron Induced Fission Fragment Tracking Experiment (NIFFTE) collaboration, in an effort to meet this need, has constructed a Time Projection Chamber (TPC) which aims to reduce the uncertainty of the fission cross-section to less than 1%. Using the Maximum Integration Data Acquisition System (MIDAS) framework, slow control measurements are integrated into a single interface to facilitate off-site monitoring. The Hart Scientific 1560 Black Stack will be used with two 2564 Thermistor Scanner Modules to monitor internal temperature of the TPC. A Prologix GPIB to Ethernet controller will be used to interface the hardware with MIDAS. This presentation will detail the design and implementation of the slow control system for the TPC. This work was supported by the U.S. Department of Energy Division of Energy Research.

Introduction to Data Acquisition 3.Let’s Acquire Data!

NASA Astrophysics Data System (ADS)

Nakanishi, Hideya; Okumura, Haruhiko

In fusion experiments, diagnostic control and logging devices are usually connected through the field bus, e.g. GP-IB. Internet technologies are often applied for their remote operation. All equipment and digitizers are driven by pre-programmed sequences, in which clocks and triggers give the essential timing for data acquisition. Data production rate and amount must be checked in comparison with the transfer and store rates. To store binary raw data safely, journaling file systems are preferably used with redundant disks (RAID) or mirroring mechanism, such as “rsync”. A proper choice of the data compression method not only reduces the storage size but also improves the I/O throughputs. DBMS is even applicable to quick search or security around the table data.

Reliability and Characterization of High Voltage Power Capacitors

DTIC Science & Technology

2014-03-01

Cable The HVPS cable is a specialized coaxial cable that utilizes a high voltage bayonet connector. The cable itself has a voltage rating in excess...the( LabVIEW(program( GPIB( CABLE ( HVPS( HVPS( COAXIAL ( CABLE ( BNC( COAXIAL ( CABLE ( BNC( COAXIAL ( CABLE ( CAPACITOR(‘C’(DATA( CAPACITOR(‘A’(DATA( Circuit...16   F.   CABLES AND CONNECTORS ...................................................................16

Comparison of sea turtle thrombocyte aggregation to human platelet aggregation in whole blood.

PubMed

Soslau, Gerald; Prest, Phillip J; Class, Reiner; George, Robert; Paladino, Frank; Violetta, Gary

2005-11-01

The endangered sea turtles are living "fossils" that afford us an opportunity to study the hemostatic process as it likely existed millions of years ago. There are essentially no data about turtle thrombocyte aggregation prior to our studies. Thrombocytes are nucleated cells that serve the same hemostatic functions as the anucleated mammalian platelet. Sea turtle thrombocytes aggregate in response to collagen and beta-thrombin. Ristocetin induces an agglutination/aggregation response indicating the presence of a von Willebrand-like receptor, GPIb, found in all mammalian platelets. Samples treated with alpha-thrombin plus gamma-thrombin followed by ristocetin results in a rapid, stronger response than ristocetin alone. These responses are inhibited by the RGDS peptide that blocks fibrinogen cross-linking of mammalian platelets via the fibrinogen receptor, GPIIb/IIIa. Three platelet-like proteins, GPIb, GPIIb/IIIa and P-selection are detected in sea turtle thrombocytes by fluorescence activated cell sorting. Turtle thrombocytes do not respond to ADP, epinephrine, serotonin, thromboxane A2 mimetic, U46619, trypsin, or alpha-thrombin and gamma-thrombin added alone. Comparison of hemostasis in sea turtles to other vertebrates could provide a framework for understanding the structure/function and evolution of these pathways and their individual components.

Agglucetin, a tetrameric C-type lectin-like venom protein, regulates endothelial cell survival and promotes angiogenesis by activating integrin {alpha}v{beta}3 signaling

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, W.-J.

2008-05-02

Agglucetin, a platelet glycoprotein (GP)Ib binding protein from Formosan Agkistrodon acutus (A. acutus) venom, could sustain human umbilical vein endothelial cell (HUVEC) proliferation and HUVEC adhering to immobilized agglucetin showed extensive spreading, which was strongly abrogated by integrin antagonists 7E3 and triflavin. Flow cytometric analyses confirmed the expression of GPIb complex on HUVEC is absent and fluorescein isothiocyanate (FITC)-agglucetin binds to HUVEC in a dose-dependent and saturable manner. Furthermore, native agglucetin specifically and dose-dependently inhibited the binding of FITC-23C6, an anti-{alpha}v{beta}3 monoclonal antibody (mAb), but not antibodies against {alpha}2 and {alpha}5, toward HUVEC and purified {alpha}v{beta}3 also bound to immobilizedmore » agglucetin-{beta} in a dose-dependent manner. Moreover, agglucetin exhibited a pro-angiogenic effect in vitro, as well as the focal adhesion kinase (FAK)-associated signaling molecules responsible for HUVEC activation were initiated by agglucetin. In conclusion, agglucetin, acting as a survival factor, promotes endothelial adhesion and angiogenesis by triggering {alpha}v{beta}3 signaling through FAK/phosphatidylinositol 3-kinase (PI3K)/Akt pathway.« less

Dual inhibition of HY023016 based on binding properties of platelet membrane receptor subunit glycoprotein Ibα and thrombin exosites.

PubMed

Chen, Qiu-Fang; Cui, Shuang; Shen, Hui-Liang; Chen, Xiang; Li, Yun-Zhan; Wu, Qian; Xu, Yun-Gen; Gong, Guo-Qing

2018-03-05

Thrombin has long been suggested as a desirable antithrombotic target, but anti-thrombin therapy without anti-platelet thereby has never achieved the ideal effect. HY023016 is a novel compound, in our previous study, it exerted better anti-thrombotic than dabigatran etexilate. The present study aims to illustrate the excess anti-thrombotic molecular mechanisms of HY023016 through thrombin anion exosites and the platelet membrane receptor subunit glycoprotein Ibα (GPIbα). HY023016 strongly inhibited the conversion of fibrinogen to fibrous may via blocking thrombin exosite I. We also discovered that HY023016 remarkably inhibited exosite II by a loss of affinity for the γ'-peptide of fibrinogen and for heparin. Furthermore, a solid phase binding assay revealed that HY023016 inhibited ristocetin-induced washed platelets bind to von Willebrand factor (vWF). In GST pull-down assay, HY023016 decreased the binding of recombinant vWF-A1 to GPIbα N-terminal. Thus, HY023016 provides an innovative idea for designing multi-targeted anti-thrombotic drugs and laying a scientific foundation for reducing "total thrombosis risk" in a clinical drug treatment. Copyright © 2018 Elsevier B.V. All rights reserved.

Crystallization and preliminary X-ray crystallographic analysis of agkicetin-C from Deinagkistrodon acutus venom

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu, Gufeng; Departments of Molecular and Cell Biology, School of Life Sciences, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026; Huang, Qingqiu

2005-01-01

The crystallization and preliminary crystallographic analysis of agkicetin-C, a well known platelet glycoprotein Ib (GPIb) antagonist from the venom of Deinagkistrodon acutus found in Anhui Province, China is reported. The crystallization and preliminary crystallographic analysis of agkicetin-C, a well known platelet glycoprotein Ib (GPIb) antagonist from the venom of Deinagkistrodon acutus found in Anhui Province, China is reported. Crystals of agkicetin-C suitable for structure determination were obtained from 1.8 M ammonium sulfate, 40 mM MES pH 6.5 with 2%(v/v) PEG 400. Interestingly, low buffer concentrations of MES seem to be necessary for crystal growth. The crystals of agkicetin-C belong tomore » space group C2, with unit-cell parameters a = 177.5, b = 97.7, c = 106.8 Å, β = 118.5°, and diffract to 2.4 Å resolution. Solution of the phase problem by the molecular-replacement method shows that there are four agkicetin-C molecules in the asymmetric unit, with a V{sub M} value of 3.4 Å{sup 3} Da{sup −1}, which corresponds to a high solvent content of approximately 64%. Self-rotation function calculations show a single well defined non-crystallographic twofold axis with features that may represent additional elements of non-crystallographic symmetry.« less

von Willebrand factor and factor VIII are independently required to form stable occlusive thrombi in injured veins

PubMed Central

Chauhan, Anil K.; Kisucka, Janka; Lamb, Colin B.; Bergmeier, Wolfgang

2007-01-01

von Willebrand factor (VWF) protects factor VIII (FVIII) from proteolysis and mediates the initial contact of platelets with the injured vessel wall, thus playing an important role in hemostasis and thrombosis. VWF is crucial for the formation of occlusive thrombi at arterial shear rates. However, with only a few conflicting studies published, the role of VWF in venous thrombosis is still unclear. Using gene-targeted mice, we show that in ferric chloride–injured veins platelet adhesion to subendothelium is decreased and thrombus growth is impaired in VWF−/− mice when compared with wild type (WT). We also observed increased embolization in the VWF−/− mice, which was due to lower FVIII levels in these mice as recombinant factor VIII (r-FVIII) restored thrombus stability. Despite normalization of blood clotting time and thrombus stability after r-FVIII infusion, the VWF−/− venules did not occlude. Transgenic platelets lacking the VWF receptor GPIbα extracellular domain showed decreased adhesion to injured veins. But, after a delay, all the injured venules occluded in these transgenic mice. Thus, VWF likely uses other adhesion receptors besides GPIbα in thrombus growth under venous shear conditions. Our studies document crucial roles for VWF and FVIII in experimental thrombosis under venous flow conditions in vivo. PMID:17119108

A LabVIEW-Based Virtual Instrument System for Laser-Induced Fluorescence Spectroscopy.

PubMed

Wu, Qijun; Wang, Lufei; Zu, Lily

2011-01-01

We report the design and operation of a Virtual Instrument (VI) system based on LabVIEW 2009 for laser-induced fluorescence experiments. This system achieves synchronous control of equipment and acquisition of real-time fluorescence data communicating with a single computer via GPIB, USB, RS232, and parallel ports. The reported VI system can also accomplish data display, saving, and analysis, and printing the results. The VI system performs sequences of operations automatically, and this system has been successfully applied to obtain the excitation and dispersion spectra of α-methylnaphthalene. The reported VI system opens up new possibilities for researchers and increases the efficiency and precision of experiments. The design and operation of the VI system are described in detail in this paper, and the advantages that this system can provide are highlighted.

A LabVIEW-Based Virtual Instrument System for Laser-Induced Fluorescence Spectroscopy

PubMed Central

Wu, Qijun; Wang, Lufei; Zu, Lily

2011-01-01

We report the design and operation of a Virtual Instrument (VI) system based on LabVIEW 2009 for laser-induced fluorescence experiments. This system achieves synchronous control of equipment and acquisition of real-time fluorescence data communicating with a single computer via GPIB, USB, RS232, and parallel ports. The reported VI system can also accomplish data display, saving, and analysis, and printing the results. The VI system performs sequences of operations automatically, and this system has been successfully applied to obtain the excitation and dispersion spectra of α-methylnaphthalene. The reported VI system opens up new possibilities for researchers and increases the efficiency and precision of experiments. The design and operation of the VI system are described in detail in this paper, and the advantages that this system can provide are highlighted. PMID:22013388

Remotely Accessible Testbed for Software Defined Radio Development

NASA Technical Reports Server (NTRS)

Lux, James P.; Lang, Minh; Peters, Kenneth J.; Taylor, Gregory H.

2012-01-01

Previous development testbeds have assumed that the developer was physically present in front of the hardware being used. No provision for remote operation of basic functions (power on/off or reset) was made, because the developer/operator was sitting in front of the hardware, and could just push the button manually. In this innovation, a completely remotely accessible testbed has been created, with all diagnostic equipment and tools set up for remote access, and using standardized interfaces so that failed equipment can be quickly replaced. In this testbed, over 95% of the operating hours were used for testing without the developer being physically present. The testbed includes a pair of personal computers, one running Linux and one running Windows. A variety of peripherals is connected via Ethernet and USB (universal serial bus) interfaces. A private internal Ethernet is used to connect to test instruments and other devices, so that the sole connection to the outside world is via the two PCs. An important design consideration was that all of the instruments and interfaces used stable, long-lived industry standards, such as Ethernet, USB, and GPIB (general purpose interface bus). There are no plug-in cards for the two PCs, so there are no problems with finding replacement computers with matching interfaces, device drivers, and installation. The only thing unique to the two PCs is the locally developed software, which is not specific to computer or operating system version. If a device (including one of the computers) were to fail or become unavailable (e.g., a test instrument needed to be recalibrated), replacing it is a straightforward process with a standard, off-the-shelf device.

Glycoprotein Ib activation by thrombin stimulates the energy metabolism in human platelets

PubMed Central

Corona de la Peña, Norma; Gutiérrez-Aguilar, Manuel; Hernández-Reséndiz, Ileana; Marín-Hernández, Álvaro

2017-01-01

Thrombin-induced platelet activation requires substantial amounts of ATP. However, the specific contribution of each ATP-generating pathway i.e., oxidative phosphorylation (OxPhos) versus glycolysis and the biochemical mechanisms involved in the thrombin-induced activation of energy metabolism remain unclear. Here we report an integral analysis on the role of both energy pathways in human platelets activated by several agonists, and the signal transducing mechanisms associated with such activation. We found that thrombin, Trap-6, arachidonic acid, collagen, A23187, epinephrine and ADP significantly increased glycolytic flux (3–38 times vs. non-activated platelets) whereas ristocetin was ineffective. OxPhos (33 times) and mitochondrial transmembrane potential (88%) were increased only by thrombin. OxPhos was the main source of ATP in thrombin-activated platelets, whereas in platelets activated by any of the other agonists, glycolysis was the principal ATP supplier. In order to establish the biochemical mechanisms involved in the thrombin-induced OxPhos activation in platelets, several signaling pathways associated with mitochondrial activation were analyzed. Wortmannin and LY294002 (PI3K/Akt pathway inhibitors), ristocetin and heparin (GPIb inhibitors) as well as resveratrol, ATP (calcium-release inhibitors) and PP1 (Tyr-phosphorylation inhibitor) prevented the thrombin-induced platelet activation. These results suggest that thrombin activates OxPhos and glycolysis through GPIb-dependent signaling involving PI3K and Akt activation, calcium mobilization and protein phosphorylation. PMID:28817667

An Experimental Investigation of Acoustic Cavitation in Gaseous Liquids

DTIC Science & Technology

1990-11-08

a time-to-amplitude converter and an analog-to- digital data acquisition system based on a microcomputer. IL B. Acoustic Levitation Apparatus L...reading the RMS -ioltage from a Fluke 8600A digital multimeter to which the pill transducer was connected. This voltage was read via a GPIB interface by...micrometer microscope model M110A was used. The rise-time was measured with a digital timer which was activated by the same push-button switch used to turn

Integrated Computer Controlled Glow Discharge Tube

NASA Astrophysics Data System (ADS)

Kaiser, Erik; Post-Zwicker, Andrew

2002-11-01

An "Interactive Plasma Display" was created for the Princeton Plasma Physics Laboratory to demonstrate the characteristics of plasma to various science education outreach programs. From high school students and teachers, to undergraduate students and visitors to the lab, the plasma device will be a key component in advancing the public's basic knowledge of plasma physics. The device is fully computer controlled using LabVIEW, a touchscreen Graphical User Interface [GUI], and a GPIB interface. Utilizing a feedback loop, the display is fully autonomous in controlling pressure, as well as in monitoring the safety aspects of the apparatus. With a digital convectron gauge continuously monitoring pressure, the computer interface analyzes the input signals, while making changes to a digital flow controller. This function works independently of the GUI, allowing the user to simply input and receive a desired pressure; quickly, easily, and intuitively. The discharge tube is a 36" x 4"id glass cylinder with 3" side port. A 3000 volt, 10mA power supply, is used to breakdown the plasma. A 300 turn solenoid was created to demonstrate the magnetic pinching of a plasma. All primary functions of the device are controlled through the GUI digital controllers. This configuration allows for operators to safely control the pressure (100mTorr-1Torr), magnetic field (0-90Gauss, 7amps, 10volts), and finally, the voltage applied across the electrodes (0-3000v, 10mA).

Three-dimensional multi-scale model of deformable platelets adhesion to vessel wall in blood flow

PubMed Central

Wu, Ziheng; Xu, Zhiliang; Kim, Oleg; Alber, Mark

2014-01-01

When a blood vessel ruptures or gets inflamed, the human body responds by rapidly forming a clot to restrict the loss of blood. Platelets aggregation at the injury site of the blood vessel occurring via platelet–platelet adhesion, tethering and rolling on the injured endothelium is a critical initial step in blood clot formation. A novel three-dimensional multi-scale model is introduced and used in this paper to simulate receptor-mediated adhesion of deformable platelets at the site of vascular injury under different shear rates of blood flow. The novelty of the model is based on a new approach of coupling submodels at three biological scales crucial for the early clot formation: novel hybrid cell membrane submodel to represent physiological elastic properties of a platelet, stochastic receptor–ligand binding submodel to describe cell adhesion kinetics and lattice Boltzmann submodel for simulating blood flow. The model implementation on the GPU cluster significantly improved simulation performance. Predictive model simulations revealed that platelet deformation, interactions between platelets in the vicinity of the vessel wall as well as the number of functional GPIbα platelet receptors played significant roles in platelet adhesion to the injury site. Variation of the number of functional GPIbα platelet receptors as well as changes of platelet stiffness can represent effects of specific drugs reducing or enhancing platelet activity. Therefore, predictive simulations can improve the search for new drug targets and help to make treatment of thrombosis patient-specific. PMID:24982253

High Energy Electron Radiation Degradation of Gallium Arsenide Solar Cells.

DTIC Science & Technology

1986-03-01

Subroutine Print Instruct ions Print / Completed/ Sample Ch . 0 Return Calculate C1 6 Print C1 IISample Ch . 2 70 -j.. .,.1-I.,.... ,.L.L...PLOTTER * 270 * AND THE CONNECTION DIAGRAM FOR THE SYSTEM MAY * 280 " * MAY BE FOUND IN CH 2, FIGURE (3). THE GPIB * 290’ * DRIVER IS REPRODUCED FROM REF...PLOT I-V CURVE ON HP 7845 PLOTTER." 2180 PRINT 2190 PRINT ř. PLOT I-V CURVE ON RGB MONITOR." 2200 PRINT 2210 PRINT Ś. WRITE I-V DATA TO FLOPPY DISK

The Cold Dark Matter Search test stand warm electronics card

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hines, Bruce; /Colorado U., Denver; Hansen, Sten

A card which does the signal processing for four SQUID amplifiers and two charge sensitive channels is described. The card performs the same functions as is presently done with two custom 9U x 280mm Eurocard modules, a commercial multi-channel VME digitizer, a PCI to GPIB interface, a PCI to VME interface and a custom built linear power supply. By integrating these functions onto a single card and using the power over Ethernet standard, the infrastructure requirements for instrumenting a Cold Dark Matter Search (CDMS) detector test stand are significantly reduced.

Oral thrombin inhibitor aggravates platelet adhesion and aggregation during arterial thrombosis.

PubMed

Petzold, Tobias; Thienel, Manuela; Konrad, Ildiko; Schubert, Irene; Regenauer, Ron; Hoppe, Boj; Lorenz, Michael; Eckart, Annekathrin; Chandraratne, Sue; Lennerz, Carsten; Kolb, Christof; Braun, Daniel; Jamasbi, Janina; Brandl, Richard; Braun, Siegmund; Siess, Wolfgang; Schulz, Christian; Massberg, Steffen

2016-11-30

In patients with atrial fibrillation, oral anticoagulation with oral thrombin inhibitors (OTIs), in contrast to vitamin K antagonists (VKAs), associates with a modest increase in acute coronary syndromes (ACSs). Whether this observation is causatively linked to OTI treatment and, if so, whether OTI action is the result of a lower antithrombotic efficacy of OTI compared to VKA or reflects a yet undefined prothrombotic activity of OTI remain unclear. We analyzed platelet function in patients receiving OTI or dose-adapted VKA under static and flow conditions. In vivo, we studied arterial thrombosis in OTI-, VKA-, and vehicle-treated mice using carotid ligation and wire injury models. Further, we examined thrombus formation on human atherosclerotic plaque homogenates under arterial shear to address the relevance to human pathology. Under static conditions, aggregation in the presence of ristocetin was increased in OTI-treated blood, whereas platelet reactivity and aggregation to other agonists were only marginally affected. Under flow conditions, firm platelet adhesion and thrombus formation on von Willebrand factor, collagen, and human atherosclerotic plaque were increased in the presence of OTI in comparison to VKA. OTI treatment was associated with increased thrombus formation in injured carotid arteries of mice. Inhibition or ablation of GPIbα-thrombin interactions abolished the effect of OTI on thrombus formation, suggesting a mechanistic role of the platelet receptor GPIbα and its thrombin-binding site. The effect of OTI was also abrogated in the presence of aspirin. In summary, OTI treatment has prothrombotic activity that might contribute to the increase in ACS observed clinically in patients. Copyright © 2016, American Association for the Advancement of Science.

Talin does not associate exclusively with alpha 2b beta 3 integrin in activated human platelets.

PubMed

Escolar, G; Diaz-Ricart, M; White, J G

1995-05-01

Talin is a high-molecular-weight protein that may stabilize connections between cytoplasmic actin and the submembrane portion of glycoprotein IIb-IIIa (GPIIb-IIIa) (alpha 2b beta 3 integrin) in thrombin-stimulated human platelets. Using morphologic and electrophoretic techniques, we have examined the association of talin with the cytoskeleton of platelets activated by thrombin in the presence of fibrinogen-coated gold particles (Fgn/Au). Ultrastructural studies confirmed the presence of Fgn/Au firmly bound to the outside membranes of detergent-extracted platelets. Immunoblots of protein bands showed GPIIIa, but not talin, associated with cytoskeletons of activated platelets. Immunogold cytochemical techniques were performed on ultrathin cryosections of whole platelets to localize talin at the ultrastructural level. Studies were performed on normal platelets and platelets defective in GPIIb-IIIa (Glanzmann's thrombasthenia) and GPIb (Bernard-Soulier syndrome). Talin was randomly distributed in the cytoplasm of resting platelets. Activation resulted in binding of Fgn/Au to the surface membrane and redistribution of talin to the submembrane region. However, no definitive colocalization between the two markers was noted. Activated thrombasthenic platelets failed to bind Fgn/Au, but talin was localized to the submembrane location. After activation, talin was confined to the submembrane zone of Bernard-Soulier syndrome platelets. No definitive colocalization was observed between large clusters of Fgn/Au-occupied receptors and talin distributed in the submembrane region. GPIb and GPIIb-IIIa are not necessary for talin to localize in the submembrane region of activated cells. Talin does not redistribute exclusively with GPIIb-IIIa, and it may stabilize connections with other glycoproteins.

The search for new antithrombotic mechanisms and therapies that may spare hemostasis.

PubMed

Plow, Edward F; Wang, Yunmei; Simon, Daniel I

2018-04-26

Current antithrombotic drugs, including widely used antiplatelet agents and anticoagulants, are associated with significant bleeding risk. Emerging experimental evidence suggests that the molecular and cellular mechanisms of hemostasis and thrombosis can be separated, thereby increasing the possibility of new antithrombotic therapeutic targets with reduced bleeding risk. We review new coagulation and platelet targets and highlight the interaction between integrin α M β 2 (Mac-1, CD11b/CD18) on leukocytes and GPIbα on platelets that seems to distinguish thrombosis from hemostasis. © 2018 by The American Society of Hematology.

Mechanical circulatory support is associated with loss of platelet receptors glycoprotein Ibα and glycoprotein VI.

PubMed

Lukito, P; Wong, A; Jing, J; Arthur, J F; Marasco, S F; Murphy, D A; Bergin, P J; Shaw, J A; Collecutt, M; Andrews, R K; Gardiner, E E; Davis, A K

2016-11-01

Essentials Relationship of acquired von Willebrand disease (VWD) and platelet dysfunction is explored. Patients with ventricular assist devices and on extracorporeal membrane oxygenation are investigated. Acquired VWD and platelet receptor shedding is demonstrated in the majority of patients. Loss of platelet adhesion receptors glycoprotein (GP) Ibα and GPVI may increase bleeding risk. Background Ventricular assist devices (VADs) and extracorporeal membrane oxygenation (ECMO) are associated with bleeding that is not fully explained by anticoagulant or antiplatelet use. Exposure of platelets to elevated shear in vitro leads to increased shedding. Objectives To investigate whether loss of platelet receptors occurs in vivo, and the relationship with acquired von Willebrand syndrome (AVWS). Methods Platelet counts, coagulation tests and von Willebrand factor (VWF) analyses were performed on samples from 21 continuous flow VAD (CF-VAD), 20 ECMO, 12 heart failure and seven aortic stenosis patients. Levels of platelet receptors were measured by flow cytometry or ELISA. Results The loss of high molecular weight VWF multimers was observed in 18 of 19 CF-VAD and 14 of 20 ECMO patients, consistent with AVWS. Platelet receptor shedding was demonstrated by elevated soluble glycoprotein (GP) VI levels in plasma and significantly reduced surface GPIbα and GPVI levels in CF-VAD and ECMO patients as compared with healthy donors. Platelet receptor levels were also significantly reduced in heart failure patients. Conclusions These data link AVWS and increased platelet receptor shedding in patients with CF-VADs or ECMO for the first time. Loss of the platelet surface receptors GPIbα and GPVI in heart failure, CF-VAD and ECMO patients may contribute to ablated platelet adhesion/activation, and limit thrombus formation under high/pathologic shear conditions. © 2016 International Society on Thrombosis and Haemostasis.

Platelets in thrombosis and hemostasis: old topic with new mechanisms.

PubMed

Wang, Yiming; Andrews, Marc; Yang, Yan; Lang, Sean; Jin, Joseph W; Cameron-Vendrig, Alison; Zhu, Guangheng; Reheman, Adili; Ni, Heyu

2012-12-01

Platelets are small anucleate cells generated from megakaryocytes in the bone marrow. After being released into the circulation, platelets play key roles in the surveillance of vascular injury, and can quickly adhere and aggregate at the site of injury, which are critical events for vascular repair and hemostasis. However, the same biological processes of platelet adhesion and aggregation may also cause thrombotic disorders. The formation of a platelet plug at sites of atherosclerotic lesion rupture is the most common mechanism leading to myocardial or cerebral infarction. Platelet-related deep vein thrombosis is also one of the leading causes of mortality worldwide. The contribution of several platelet receptors and their ligands has been highlighted in these processes. In platelet adhesion, particularly at high shear stress, GPIbα-von Willebrand factor (VWF) interaction may initiate this event, which is followed by GPVI signalling and firm platelet adhesion mediated by members of the integrin family, such as β3 (αIIbβ3) and β1 (α2β1, α5β1) integrins. In platelet aggregation, although GPIbα-VWF, P selectin-sulfatides, and other molecules, may be involved, the process is mainly mediated by β3 (αIIbβ3) integrin and its ligands, such as fibrinogen and VWF. It is intriguing that platelet adhesion and aggregation still occur in mice lacking both fibrinogen and VWF, suggesting that other unforeseen molecule(s) may also be important in these processes. Identification and characterization of these molecules will enrich our knowledge in the basic science of hemostasis and thrombosis, and may lead to the development of new therapies against bleeding disorders and thrombotic diseases.

Intraplatelet reactive oxygen species (ROS) correlate with the shedding of adhesive receptors, microvesiculation and platelet adhesion to collagen during storage: Does endogenous ROS generation downregulate platelet adhesive function?

PubMed

Ghasemzadeh, Mehran; Hosseini, Ehteramolsadat; Roudsari, Zahra Oushyani; Zadkhak, Parvin

2018-03-01

Platelets storage lesion is mainly orchestrated by platelet activating signals during storage. Reactive oxygen species (ROS) are being considered as important signaling molecules modulating platelet function while their production has also been shown to be augmented by platelet activation. This study investigated to what extent endogenous ROS generation during platelet storage could be correlated with platelet receptor shedding, microvesiculation and adhesive function. 10 PRP-platelet concentrates were subjected to flow cytometry analysis to examine the generation of intraplatelet ROS on days 1, 5 and 7 after storage. In 5 day-stored platelets considering 40% of ROS generation as a cutoff point, samples were divided into two groups of those with higher or lower levels of ROS. The expression of adhesion receptors (GPVI, GPIbα), the amount of microparticles and phosphatidylserine exposure in each group were then examined by flow cytometry. Platelet receptor shedding and adhesion to collagen matrix were respectively measured by western blotting and microscopic assays. Our data showed lowered expression of GPIbα (p < 0.05) and GPVI in samples with ROS > 40% than those with ROS ≤ 40%, whereas receptors shedding and microvesiculation were (p < 0.05) elevated in platelets with higher levels of ROS. Functionally, we observed significantly (p < 0.05) lower levels of platelet adhesion to collagen matrix in samples with ROS generation more than 40%. Taken together, we showed correlations between intraplatelet ROS generation and either platelet receptors or microparticle shedding as well as platelet adhesive capacity to collagen. These findings suggest that augmented ROS generation during storage might be relevant to down-regulation of platelet adhesive function. Copyright © 2018 Elsevier Ltd. All rights reserved.

Influence of genetic variations in platelet glycoproteins and eNOS in the development of arterial ischaemia of lower limbs in type 2 diabetes mellitus patients.

PubMed

Carvalhais, Virginia; Ruivães, Ema; Pina-Cabral, Luis Bernardo; Mesquita, Bárbara; Oliveira, Flávio; Monteiro, Maria Céu; Criado, Maria Begoña

2016-12-01

Endothelial and platelet dysfunction increase the atherothrombotic risk in diabetes mellitus patients. Therefore, arterial ischaemia of lower limbs is an important complication in diabetes mellitus. In the present work, type 2 diabetic patients were classified by a podiatrist into presence or absence of arterial ischaemia of lower limbs. Several polymorphisms in platelet glycoproteins and eNOS genes were evaluated. Our results suggest that the -5CC genotype in Kozak sequence of GPIbα may be associated with a higher risk of developing arterial ischaemia of lower limbs in type 2 diabetes mellitus patients. Copyright © 2016 Elsevier Ltd. All rights reserved.

Dual roles for hepatic lectin receptors in the clearance of chilled platelets

PubMed Central

Rumjantseva, Viktoria; Grewal, Prabhjit K.; Wandall, Hans H.; Josefsson, Emma C.; Sørensen, Anne Louise; Larson, Göran; Marth, Jamey D.; Hartwig, John H.; Hoffmeister, Karin M.

2015-01-01

Chilling rapidly (<4 h) clusters Glycoprotein - (GP)Ib receptors on blood platelets, and ß2-integrins of hepatic macrophages bind ßGlcNAc residues in the clusters leading to rapid clearance of acutely chilled platelets following transfusion. Although capping the ßGlcNAc moieties by galactosylation prevents clearance, this strategy is ineffective after prolonged (>24 h) refrigeration. We report here that prolonged refrigeration increases the density/concentration of exposed galactose residues such that hepatocytes become increasingly involved in the removal of platelets using their Ashwell-Morell receptors. Macrophages always rapidly remove a large fraction of transfused platelets (~40%). With platelet cooling, hepatocyte-dependent clearance further diminishes their recoveries following transfusion. PMID:19783995

Von Willebrand's disease with spontaneous platelet aggregation induced by an abnormal plasma von Willebrand factor.

PubMed Central

Grainick, H R; Williams, S B; McKeown, L P; Rick, M E; Maisonneuve, P; Jenneau, C; Sultan, Y

1985-01-01

We have investigated and characterized the abnormalities in four unrelated patients with von Willebrand's disease (vWd) who have (a) enhanced ristocetin-induced platelet aggregation (RIPA) at low ristocetin concentrations, (b) absence of the largest plasma von Willebrand factor (vWf) multimers, and (c) thrombocytopenia. The platelet-rich plasma of these patients aggregates spontaneously without the addition of any agonists. When isolated normal platelets are resuspended in patient plasma spontaneous aggregation occurs; however, the patients' plasmas did not induce platelet aggregation of normal washed formalinized platelets. When the patients' platelets are suspended in normal plasma, spontaneous aggregation is not observed. The spontaneous platelet aggregation (SPA) is associated with dense granule secretion as measured by ATP release and alpha granule release as measured by beta-thromboglobulin and platelet factor 4 release. The SPA is totally inhibited by 5 mM EDTA, prostaglandin I2, and dibutryl cyclic AMP, while it is only partially inhibited by 1 mM EDTA, acetylsalicylic acid, or apyrase. A monoclonal antibody directed against glycoprotein Ib (GPIb) and/or a monoclonal antibody against the glycoprotein IIb/IIIa (GPIIb/IIIa) complex totally inhibits the SPA. The vWf was isolated from the plasma of one of these patients. The purified vWf induced platelet aggregation of normal platelets resuspended in either normal or severe vWd plasma, but the vWf did not induce platelet aggregation of normal platelets resuspended in afibrinognemic plasma. Sialic acid and galactose quantification of the patient's vWf revealed approximately a 50% reduction compared with normal vWf. These studies indicate that a form of vWd exists, which is characterized by SPA that is induced by the abnormal plasma vWf. The SPA is dependent on the presence of plasma fibrinogen, and the availability of the GPIb and the GPIIb/IIIa complex. In this variant form of vWd the abnormal vWf causes enhanced RIPA, SPA, and thrombocytopenia. Images PMID:2932469

Identification of a new mutation in platelet glycoprotein IX (GPIX) in a patient with Bernard-Soulier syndrome.

PubMed

Rivera, C E; Villagra, J; Riordan, M; Williams, S; Lindstrom, K J; Rick, M E

2001-01-01

We describe a new mutation in glycoprotein IX (GPIX) in a patient with Bernard-Soulier syndrome (BSS). Sequencing of GPIX revealed a homozygous (T-->C) transition at nucleotide 1717 (GenBank/HUMGPIX/M80478), resulting in a Cys(8) (TGT)-->Arg (CGT) replacement in the mature peptide. DNA restriction enzyme analysis using BsaAI revealed that the patient was homozygous and that his parents were heterozygous for the defect. This mutation disrupts a putative disulphide bond between the Cys(8) and Cys(12) that would alter the secondary structure of GPIX and which probably accounts for the absence of the GPIb/IX/V complex from the platelet surface in this patient.

Advanced communications technology satellite high burst rate link evaluation terminal power control and rain fade software test plan, version 1.0

NASA Technical Reports Server (NTRS)

Reinhart, Richard C.

1993-01-01

The Power Control and Rain Fade Software was developed at the NASA Lewis Research Center to support the Advanced Communications Technology Satellite High Burst Rate Link Evaluation Terminal (ACTS HBR-LET). The HBR-LET is an experimenters terminal to communicate with the ACTS for various experiments by government, university, and industry agencies. The Power Control and Rain Fade Software is one segment of the Control and Performance Monitor (C&PM) Software system of the HBR-LET. The Power Control and Rain Fade Software automatically controls the LET uplink power to compensate for signal fades. Besides power augmentation, the C&PM Software system is also responsible for instrument control during HBR-LET experiments, control of the Intermediate Frequency Switch Matrix on board the ACTS to yield a desired path through the spacecraft payload, and data display. The Power Control and Rain Fade Software User's Guide, Version 1.0 outlines the commands and procedures to install and operate the Power Control and Rain Fade Software. The Power Control and Rain Fade Software Maintenance Manual, Version 1.0 is a programmer's guide to the Power Control and Rain Fade Software. This manual details the current implementation of the software from a technical perspective. Included is an overview of the Power Control and Rain Fade Software, computer algorithms, format representations, and computer hardware configuration. The Power Control and Rain Fade Test Plan provides a step-by-step procedure to verify the operation of the software using a predetermined signal fade event. The Test Plan also provides a means to demonstrate the capability of the software.

Automatic tuned MRI RF coil for multinuclear imaging of small animals at 3T.

PubMed

Muftuler, L Tugan; Gulsen, Gultekin; Sezen, Kumsal D; Nalcioglu, Orhan

2002-03-01

We have developed an MRI RF coil whose tuning can be adjusted automatically between 120 and 128 MHz for sequential spectroscopic imaging of hydrogen and fluorine nuclei at field strength 3 T. Variable capacitance (varactor) diodes were placed on each rung of an eight-leg low-pass birdcage coil to change the tuning frequency of the coil. The diode junction capacitance can be controlled by the amount of applied reverse bias voltage. Impedance matching was also done automatically by another pair of varactor diodes to obtain the maximum SNR at each frequency. The same bias voltage was applied to the tuning varactors on all rungs to avoid perturbations in the coil. A network analyzer was used to monitor matching and tuning of the coil. A Pentium PC controlled the analyzer through the GPIB bus. A code written in LABVIEW was used to communicate with the network analyzer and adjust the bias voltages of the varactors via D/A converters. Serially programmed D/A converter devices were used to apply the bias voltages to the varactors. Isolation amplifiers were used together with RF choke inductors to provide isolation between the RF coil and the DC bias lines. We acquired proton and fluorine images sequentially from a multicompartment phantom using the designed coil. Good matching and tuning were obtained at both resonance frequencies. The tuning and matching of the coil were changed from one resonance frequency to the other within 60 s. (c) 2002 Elsevier Science (USA).

Guidance and Control Software Project Data - Volume 4: Configuration Management and Quality Assurance Documents

NASA Technical Reports Server (NTRS)

Hayhurst, Kelly J. (Editor)

2008-01-01

The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes configuration management and quality assurance documents from the GCS project. Volume 4 contains six appendices: A. Software Accomplishment Summary for the Guidance and Control Software Project; B. Software Configuration Index for the Guidance and Control Software Project; C. Configuration Management Records for the Guidance and Control Software Project; D. Software Quality Assurance Records for the Guidance and Control Software Project; E. Problem Report for the Pluto Implementation of the Guidance and Control Software Project; and F. Support Documentation Change Reports for the Guidance and Control Software Project.

SEPAC software configuration control plan and procedures, revision 1

NASA Technical Reports Server (NTRS)

1981-01-01

SEPAC Software Configuration Control Plan and Procedures are presented. The objective of the software configuration control is to establish the process for maintaining configuration control of the SEPAC software beginning with the baselining of SEPAC Flight Software Version 1 and encompass the integration and verification tests through Spacelab Level IV Integration. They are designed to provide a simplified but complete configuration control process. The intent is to require a minimum amount of paperwork but provide total traceability of SEPAC software.

Guidance and Control Software Project Data - Volume 1: Planning Documents

NASA Technical Reports Server (NTRS)

Hayhurst, Kelly J. (Editor)

2008-01-01

The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes the planning documents from the GCS project. Volume 1 contains five appendices: A. Plan for Software Aspects of Certification for the Guidance and Control Software Project; B. Software Development Standards for the Guidance and Control Software Project; C. Software Verification Plan for the Guidance and Control Software Project; D. Software Configuration Management Plan for the Guidance and Control Software Project; and E. Software Quality Assurance Activities.

A Structural Model for Binding of the Serine-Rich Repeat Adhesin GspB to Host Carbohydrate Receptors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pyburn, Tasia M.; Bensing, Barbara A.; Xiong, Yan Q.

2014-10-02

GspB is a serine-rich repeat (SRR) adhesin of Streptococcus gordonii that mediates binding of this organism to human platelets via its interaction with sialyl-T antigen on the receptor GPIb{alpha}. This interaction appears to be a major virulence determinant in the pathogenesis of infective endocarditis. To address the mechanism by which GspB recognizes its carbohydrate ligand, we determined the high-resolution x-ray crystal structure of the GspB binding region (GspB{sub BR}), both alone and in complex with a disaccharide precursor to sialyl-T antigen. Analysis of the GspB{sub BR} structure revealed that it is comprised of three independently folded subdomains or modules: (1)more » an Ig-fold resembling a CnaA domain from prokaryotic pathogens; (2) a second Ig-fold resembling the binding region of mammalian Siglecs; (3) a subdomain of unique fold. The disaccharide was found to bind in a pocket within the Siglec subdomain, but at a site distinct from that observed in mammalian Siglecs. Confirming the biological relevance of this binding pocket, we produced three isogenic variants of S. gordonii, each containing a single point mutation of a residue lining this binding pocket. These variants have reduced binding to carbohydrates of GPIb{alpha}. Further examination of purified GspB{sub BR}-R484E showed reduced binding to sialyl-T antigen while S. gordonii harboring this mutation did not efficiently bind platelets and showed a significant reduction in virulence, as measured by an animal model of endocarditis. Analysis of other SRR proteins revealed that the predicted binding regions of these adhesins also had a modular organization, with those known to bind carbohydrate receptors having modules homologous to the Siglec and Unique subdomains of GspBBR. This suggests that the binding specificity of the SRR family of adhesins is determined by the type and organization of discrete modules within the binding domains, which may affect the tropism of organisms for different tissues.« less

Guidance and Control Software Project Data - Volume 3: Verification Documents

NASA Technical Reports Server (NTRS)

Hayhurst, Kelly J. (Editor)

2008-01-01

The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes the verification documents from the GCS project. Volume 3 contains four appendices: A. Software Verification Cases and Procedures for the Guidance and Control Software Project; B. Software Verification Results for the Pluto Implementation of the Guidance and Control Software; C. Review Records for the Pluto Implementation of the Guidance and Control Software; and D. Test Results Logs for the Pluto Implementation of the Guidance and Control Software.

49 CFR 236.18 - Software management control plan.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Software management control plan. 236.18 Section... Instructions: All Systems General § 236.18 Software management control plan. (a) Within 6 months of June 6, 2005, each railroad shall develop and adopt a software management control plan for its signal and train...

49 CFR 236.18 - Software management control plan.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Software management control plan. 236.18 Section... Instructions: All Systems General § 236.18 Software management control plan. (a) Within 6 months of June 6, 2005, each railroad shall develop and adopt a software management control plan for its signal and train...

49 CFR 236.18 - Software management control plan.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Software management control plan. 236.18 Section... Instructions: All Systems General § 236.18 Software management control plan. (a) Within 6 months of June 6, 2005, each railroad shall develop and adopt a software management control plan for its signal and train...

49 CFR 236.18 - Software management control plan.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Software management control plan. 236.18 Section... Instructions: All Systems General § 236.18 Software management control plan. (a) Within 6 months of June 6, 2005, each railroad shall develop and adopt a software management control plan for its signal and train...

49 CFR 236.18 - Software management control plan.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Software management control plan. 236.18 Section... Instructions: All Systems General § 236.18 Software management control plan. (a) Within 6 months of June 6, 2005, each railroad shall develop and adopt a software management control plan for its signal and train...

Software and electronic developments for TUG - T60 robotic telescope

NASA Astrophysics Data System (ADS)

Parmaksizoglu, M.; Dindar, M.; Kirbiyik, H.; Helhel, S.

2014-12-01

A robotic telescope is a telescope that can make observations without hands-on human control. Its low level behavior is automatic and computer-controlled. Robotic telescopes usually run under the control of a scheduler, which provides high-level control by selecting astronomical targets for observation. TUBITAK National Observatory (TUG) T60 Robotic Telescope is controlled by open source OCAAS software, formally named TALON. This study introduces the improvements on TALON software, new electronic and mechanic designs. The designs and software improvements were implemented in the T60 telescope control software and tested on the real system successfully.

The Application of Software Safety to the Constellation Program Launch Control System

NASA Technical Reports Server (NTRS)

Kania, James; Hill, Janice

2011-01-01

The application of software safety practices on the LCS project resulted in the successful implementation of the NASA Software Safety Standard NASA-STD-8719.138 and CxP software safety requirements. The GOP-GEN-GSW-011 Hazard Report was the first report developed at KSC to identify software hazard causes and their controls. This approach can be applied to similar large software - intensive systems where loss of control can lead to a hazard.

Using formal specification in the Guidance and Control Software (GCS) experiment. Formal design and verification technology for life critical systems

NASA Technical Reports Server (NTRS)

Weber, Doug; Jamsek, Damir

1994-01-01

The goal of this task was to investigate how formal methods could be incorporated into a software engineering process for flight-control systems under DO-178B and to demonstrate that process by developing a formal specification for NASA's Guidance and Controls Software (GCS) Experiment. GCS is software to control the descent of a spacecraft onto a planet's surface. The GCS example is simplified from a real example spacecraft, but exhibits the characteristics of realistic spacecraft control software. The formal specification is written in Larch.

Open source software to control Bioflo bioreactors.

PubMed

Burdge, David A; Libourel, Igor G L

2014-01-01

Bioreactors are designed to support highly controlled environments for growth of tissues, cell cultures or microbial cultures. A variety of bioreactors are commercially available, often including sophisticated software to enhance the functionality of the bioreactor. However, experiments that the bioreactor hardware can support, but that were not envisioned during the software design cannot be performed without developing custom software. In addition, support for third party or custom designed auxiliary hardware is often sparse or absent. This work presents flexible open source freeware for the control of bioreactors of the Bioflo product family. The functionality of the software includes setpoint control, data logging, and protocol execution. Auxiliary hardware can be easily integrated and controlled through an integrated plugin interface without altering existing software. Simple experimental protocols can be entered as a CSV scripting file, and a Python-based protocol execution model is included for more demanding conditional experimental control. The software was designed to be a more flexible and free open source alternative to the commercially available solution. The source code and various auxiliary hardware plugins are publicly available for download from https://github.com/LibourelLab/BiofloSoftware. In addition to the source code, the software was compiled and packaged as a self-installing file for 32 and 64 bit windows operating systems. The compiled software will be able to control a Bioflo system, and will not require the installation of LabVIEW.

Open Source Software to Control Bioflo Bioreactors

PubMed Central

Burdge, David A.; Libourel, Igor G. L.

2014-01-01

Bioreactors are designed to support highly controlled environments for growth of tissues, cell cultures or microbial cultures. A variety of bioreactors are commercially available, often including sophisticated software to enhance the functionality of the bioreactor. However, experiments that the bioreactor hardware can support, but that were not envisioned during the software design cannot be performed without developing custom software. In addition, support for third party or custom designed auxiliary hardware is often sparse or absent. This work presents flexible open source freeware for the control of bioreactors of the Bioflo product family. The functionality of the software includes setpoint control, data logging, and protocol execution. Auxiliary hardware can be easily integrated and controlled through an integrated plugin interface without altering existing software. Simple experimental protocols can be entered as a CSV scripting file, and a Python-based protocol execution model is included for more demanding conditional experimental control. The software was designed to be a more flexible and free open source alternative to the commercially available solution. The source code and various auxiliary hardware plugins are publicly available for download from https://github.com/LibourelLab/BiofloSoftware. In addition to the source code, the software was compiled and packaged as a self-installing file for 32 and 64 bit windows operating systems. The compiled software will be able to control a Bioflo system, and will not require the installation of LabVIEW. PMID:24667828

Advanced Communications Technology Satellite high burst rate link evaluation terminal experiment control and monitor software maintenance manual, version 1.0

NASA Technical Reports Server (NTRS)

Reinhart, Richard C.

1992-01-01

The Experiment Control and Monitor (EC&M) software was developed at NASA Lewis Research Center to support the Advanced Communications Technology Satellite (ACTS) High Burst Rate Link Evaluation Terminal (HBR-LET). The HBR-LET is an experimenter's terminal to communicate with the ACTS for various investigations by government agencies, universities, and industry. The EC&M software is one segment of the Control and Performance Monitoring (C&PM) software system of the HBR-LET. The EC&M software allows users to initialize, control, and monitor the instrumentation within the HBR-LET using a predefined sequence of commands. Besides instrument control, the C&PM software system is also responsible for computer communication between the HBR-LET and the ACTS NASA Ground Station and for uplink power control of the HBR-LET to demonstrate power augmentation during rain fade events. The EC&M Software User's Guide, Version 1.0 (NASA-CR-189160) outlines the commands required to install and operate the EC&M software. Input and output file descriptions, operator commands, and error recovery procedures are discussed in the document. The EC&M Software Maintenance Manual, Version 1.0 (NASA-CR-189161) is a programmer's guide that describes current implementation of the EC&M software from a technical perspective. An overview of the EC&M software, computer algorithms, format representation, and computer hardware configuration are included in the manual.

Architecture of the software for LAMOST fiber positioning subsystem

NASA Astrophysics Data System (ADS)

Peng, Xiaobo; Xing, Xiaozheng; Hu, Hongzhuan; Zhai, Chao; Li, Weimin

2004-09-01

The architecture of the software which controls the LAMOST fiber positioning sub-system is described. The software is composed of two parts as follows: a main control program in a computer and a unit controller program in a MCS51 single chip microcomputer ROM. And the function of the software includes: Client/Server model establishment, observation planning, collision handling, data transmission, pulse generation, CCD control, image capture and processing, and data analysis etc. Particular attention is paid to the ways in which different parts of the software can communicate. Also software techniques for multi threads, SOCKET programming, Microsoft Windows message response, and serial communications are discussed.

In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling.

PubMed

Nishimura, Satoshi; Manabe, Ichiro; Nagasaki, Mika; Kakuta, Shigeru; Iwakura, Yoichiro; Takayama, Naoya; Ooehara, Jun; Otsu, Makoto; Kamiya, Akihide; Petrich, Brian G; Urano, Tetsumei; Kadono, Takafumi; Sato, Shinichi; Aiba, Atsu; Yamashita, Hiroshi; Sugiura, Seiryo; Kadowaki, Takashi; Nakauchi, Hiromitsu; Eto, Koji; Nagai, Ryozo

2012-02-23

The mechanism by which thrombotic vessel occlusion occurs independently of plaque development or endothelial cell (EC) disruption remains unclear, largely because of an inability to visualize the formation of thrombus, especially at the single-platelet level in real time. Here we demonstrate that rapidly developing thrombi composed of discoid platelets can be induced in the mesenteric capillaries, arterioles, and large-sized arteries of living mice, enabling characterization of the kinetics of thrombosis initiation and the multicellular interrelationships during thrombus development. Platelet aggregation without EC disruption was triggered by reactive oxygen species (ROS) photochemically induced by moderate power laser irradiation. The inflammatory cytokines TNF-α and IL-1 could be key components of the EC response, acting through regulation of VWF mobilization to the cell surface. Thrombus formation was then initiated by the binding of platelet GPIbα to endothelial VWF in our model, and this effect was inhibited by the ROS scavenger N-acetylcysteine. Actin linker talin-dependent activation of alphaIIb-beta3 integrin or Rac1 in platelets was required for late-phase thrombus stability. Our novel imaging technology illustrates the molecular mechanism underlying inflammation-based thrombus formation by discoid platelets on undisrupted ECs and suggests control of ROS could be a useful therapeutic target for the prevention of thrombotic diseases.

Advanced communications technology satellite high burst rate link evaluation terminal experiment control and monitor software user's guide, version 1.0

NASA Technical Reports Server (NTRS)

Reinhart, Richard C.

1992-01-01

The Experiment Control and Monitor (EC&M) software was developed at NASA Lewis Research Center to support the Advanced Communications Technology Satellite (ACTS) High Burst Rate Link Evaluation Terminal (HBR-LET). The HBR-LET is an experimenter's terminal to communicate with the ACTS for various investigations by government agencies, universities, and industry. The EC&M software is one segment of the Control and Performance Monitoring (C&PM) software system of the HBR-LET. The EC&M software allows users to initialize, control, and monitor the instrumentation within the HBR-LET using a predefined sequence of commands. Besides instrument control, the C&PM software system is also responsible for computer communication between the HBR-LET and the ACTS NASA Ground Station and for uplink power control of the HBR-LET to demonstrate power augmentation during rain fade events. The EC&M Software User's Guide, Version 1.0 (NASA-CR-189160) outlines the commands required to install and operate the EC&M software. Input and output file descriptions, operator commands, and error recovery procedures are discussed in the document.

Advanced transport operating system software upgrade: Flight management/flight controls software description

NASA Technical Reports Server (NTRS)

Clinedinst, Winston C.; Debure, Kelly R.; Dickson, Richard W.; Heaphy, William J.; Parks, Mark A.; Slominski, Christopher J.; Wolverton, David A.

1988-01-01

The Flight Management/Flight Controls (FM/FC) software for the Norden 2 (PDP-11/70M) computer installed on the NASA 737 aircraft is described. The software computes the navigation position estimates, guidance commands, those commands to be issued to the control surfaces to direct the aircraft in flight based on the modes selected on the Advanced Guidance Control System (AGSC) mode panel, and the flight path selected via the Navigation Control/Display Unit (NCDU).

Shuttle avionics software trials, tribulations and success

NASA Technical Reports Server (NTRS)

Henderson, O. L.

1985-01-01

The early problems and the solutions developed to provide the required quality software needed to support the space shuttle engine development program are described. The decision to use a programmable digital control system on the space shuttle engine was primarily based upon the need for a flexible control system capable of supporting the total engine mission on a large complex pump fed engine. The mission definition included all control phases from ground checkout through post shutdown propellant dumping. The flexibility of the controller through reprogrammable software allowed the system to respond to the technical challenges and innovation required to develop both the engine and controller hardware. This same flexibility, however, placed a severe strain on the capability of the software development and verification organization. The overall development program required that the software facility accommodate significant growth in both the software requirements and the number of software packages delivered. This challenge was met by reorganization and evolution in the process of developing and verifying software.

Advanced communications technology satellite high burst rate link evaluation terminal communication protocol software user's guide, version 1.0

NASA Technical Reports Server (NTRS)

Reinhart, Richard C.

1993-01-01

The Communication Protocol Software was developed at the NASA Lewis Research Center to support the Advanced Communications Technology Satellite High Burst Rate Link Evaluation Terminal (ACTS HBR-LET). The HBR-LET is an experimenters terminal to communicate with the ACTS for various experiments by government, university, and industry agencies. The Communication Protocol Software is one segment of the Control and Performance Monitor (C&PM) Software system of the HBR-LET. The Communication Protocol Software allows users to control and configure the Intermediate Frequency Switch Matrix (IFSM) on board the ACTS to yield a desired path through the spacecraft payload. Besides IFSM control, the C&PM Software System is also responsible for instrument control during HBR-LET experiments, uplink power control of the HBR-LET to demonstrate power augmentation during signal fade events, and data display. The Communication Protocol Software User's Guide, Version 1.0 (NASA CR-189162) outlines the commands and procedures to install and operate the Communication Protocol Software. Configuration files used to control the IFSM, operator commands, and error recovery procedures are discussed. The Communication Protocol Software Maintenance Manual, Version 1.0 (NASA CR-189163, to be published) is a programmer's guide to the Communication Protocol Software. This manual details the current implementation of the software from a technical perspective. Included is an overview of the Communication Protocol Software, computer algorithms, format representations, and computer hardware configuration. The Communication Protocol Software Test Plan (NASA CR-189164, to be published) provides a step-by-step procedure to verify the operation of the software. Included in the Test Plan is command transmission, telemetry reception, error detection, and error recovery procedures.

Project W-211, initial tank retrieval systems, retrieval control system software configuration management plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

RIECK, C.A.

1999-02-23

This Software Configuration Management Plan (SCMP) provides the instructions for change control of the W-211 Project, Retrieval Control System (RCS) software after initial approval/release but prior to the transfer of custody to the waste tank operations contractor. This plan applies to the W-211 system software developed by the project, consisting of the computer human-machine interface (HMI) and programmable logic controller (PLC) software source and executable code, for production use by the waste tank operations contractor. The plan encompasses that portion of the W-211 RCS software represented on project-specific AUTOCAD drawings that are released as part of the C1 definitive designmore » package (these drawings are identified on the drawing list associated with each C-1 package), and the associated software code. Implementation of the plan is required for formal acceptance testing and production release. The software configuration management plan does not apply to reports and data generated by the software except where specifically identified. Control of information produced by the software once it has been transferred for operation is the responsibility of the receiving organization.« less

A software control system for the ACTS high-burst-rate link evaluation terminal

NASA Technical Reports Server (NTRS)

Reinhart, Richard C.; Daugherty, Elaine S.

1991-01-01

Control and performance monitoring of NASA's High Burst Rate Link Evaluation Terminal (HBR-LET) is accomplished by using several software control modules. Different software modules are responsible for controlling remote radio frequency (RF) instrumentation, supporting communication between a host and a remote computer, controlling the output power of the Link Evaluation Terminal and data display. Remote commanding of microwave RF instrumentation and the LET digital ground terminal allows computer control of various experiments, including bit error rate measurements. Computer communication allows system operators to transmit and receive from the Advanced Communications Technology Satellite (ACTS). Finally, the output power control software dynamically controls the uplink output power of the terminal to compensate for signal loss due to rain fade. Included is a discussion of each software module and its applications.

Statistical modeling of software reliability

NASA Technical Reports Server (NTRS)

Miller, Douglas R.

1992-01-01

This working paper discusses the statistical simulation part of a controlled software development experiment being conducted under the direction of the System Validation Methods Branch, Information Systems Division, NASA Langley Research Center. The experiment uses guidance and control software (GCS) aboard a fictitious planetary landing spacecraft: real-time control software operating on a transient mission. Software execution is simulated to study the statistical aspects of reliability and other failure characteristics of the software during development, testing, and random usage. Quantification of software reliability is a major goal. Various reliability concepts are discussed. Experiments are described for performing simulations and collecting appropriate simulated software performance and failure data. This data is then used to make statistical inferences about the quality of the software development and verification processes as well as inferences about the reliability of software versions and reliability growth under random testing and debugging.

Dual roles for hepatic lectin receptors in the clearance of chilled platelets.

PubMed

Rumjantseva, Viktoria; Grewal, Prabhjit K; Wandall, Hans H; Josefsson, Emma C; Sørensen, Anne Louise; Larson, Göran; Marth, Jamey D; Hartwig, John H; Hoffmeister, Karin M

2009-11-01

Rapid chilling causes glycoprotein-Ib (GPIb) receptors to cluster on blood platelets. Hepatic macrophage beta(2) integrin binding to beta-N-acetylglucosamine (beta-GlcNAc) residues in the clusters leads to rapid clearance of acutely chilled platelets after transfusion. Although capping the beta-GlcNAc moieties by galactosylation prevents clearance of short-term-cooled platelets, this strategy is ineffective after prolonged refrigeration. We report here that prolonged refrigeration increased the density and concentration of exposed galactose residues on platelets such that hepatocytes, through Ashwell-Morell receptor binding, become increasingly involved in platelet removal. Macrophages rapidly removed a large fraction of transfused platelets independent of their storage conditions. With prolonged platelet chilling, hepatocyte-dependent clearance further diminishes platelet recovery and survival after transfusion. Inhibition of chilled platelet clearance by both beta(2) integrin and Ashwell-Morell receptors may afford a potentially simple method for storing platelets in the cold.

Nucleation of platelets with bloodborne pathogens on Kupffer cell precedes other innate immunity and contributes to bacterial clearance

PubMed Central

Wong, Connie H. Y.; Jenne, Craig N.; Petri, Björn; Chrobok, Navina L.; Kubes, Paul

2016-01-01

Using intravital imaging of the liver, we unveil a collaborative role for platelets with Kupffer cells (KCs) in eradicating bloodborne bacterial infections. Under basal conditions, platelets via glycoprotein Ib (GPIb) formed transient “touch-and-go” interactions with von Willebrand factor (vWF) constitutively expressed on KCs. Bacteria, such as Bacillus cereus and Methicillin-resistant Staphylococcus aureus (MRSA), were rapidly caught by KCs and triggered platelets to switch from “touch-and-go” to sustained GPIIb-mediated adhesion on the KC surface to encase the bacterium. Infected GpIbα−/− mice demonstrated increased endothelial and KC damage, leading to increased fluid leakage, significant polycythemia and rapid mortality. This study identifies a novel surveillance mechanism of intravascular macrophage by platelets that rapidly converts to a critical host response against bloodborne bacteria. PMID:23770641

The clearance mechanism of chilled blood platelets.

PubMed

Hoffmeister, Karin M; Felbinger, Thomas W; Falet, Hervé; Denis, Cécile V; Bergmeier, Wolfgang; Mayadas, Tanya N; von Andrian, Ulrich H; Wagner, Denisa D; Stossel, Thomas P; Hartwig, John H

2003-01-10

Platelet transfusion is a very common lifesaving medical procedure. Not widely known is the fact that platelets, unlike other blood cells, rapidly leave the circulation if refrigerated prior to transfusion. This peculiarity requires blood services to store platelets at room temperature, limiting platelet supplies for clinical needs. Here, we describe the mechanism of this clearance system, a longstanding mystery. Chilling platelets clusters their von Willebrand (vWf) receptors, eliciting recognition of mouse and human platelets by hepatic macrophage complement type 3 (CR3) receptors. CR3-expressing but not CR3-deficient mice exposed to cold rapidly decrease platelet counts. Cooling primes platelets for activation. We propose that platelets are thermosensors, primed at peripheral sites where most injuries occurred throughout evolution. Clearance prevents pathologic thrombosis by primed platelets. Chilled platelets bind vWf and function normally in vitro and ex vivo after transfusion into CR3-deficient mice. Therefore, GPIb modification might permit cold platelet storage.

Portability scenarios for intelligent robotic control agent software

NASA Astrophysics Data System (ADS)

Straub, Jeremy

2014-06-01

Portability scenarios are critical in ensuring that a piece of AI control software will run effectively across the collection of craft that it is required to control. This paper presents scenarios for control software that is designed to control multiple craft with heterogeneous movement and functional characteristics. For each prospective target-craft type, its capabilities, mission function, location, communications capabilities and power profile are presented and performance characteristics are reviewed. This work will inform future work related to decision making related to software capabilities, hardware control capabilities and processing requirements.

The Design and Realization of Radio Telescope Control Software in Windows XP System with VC++

NASA Astrophysics Data System (ADS)

Zhao, Rong-Bing; Aili, Yu; Zhang, Jin; Yu, Yun

2007-03-01

The main function of the radio telescope control software is to drive the radio telescope to track the target accurately. The design of radio telescope control software is based on Windows XP system with VC++. The functions of the software, communication mode and the user interface is introduced in this article.

Arbitrating Control of Control and Display Units

NASA Technical Reports Server (NTRS)

Sugden, Paul C.

2007-01-01

The ARINC 739 Switch is a computer program that arbitrates control of two multi-function control and display units (MCDUs) between (1) a commercial flight-management computer (FMC) and (2) NASA software used in research on transport aircraft. (MCDUs are the primary interfaces between pilots and FMCs on many commercial aircraft.) This program was recently redesigned into a software library that can be embedded in research application programs. As part of the redesign, this software was combined with software for creating custom pages of information to be displayed on a CDU. This software commands independent switching of the left (pilot s) and right (copilot s) MCDUs. For example, a custom CDU page can control the left CDU while the FMC controls the right CDU. The software uses menu keys to switch control of the CDU between the FMC or a custom CDU page. The software provides an interface that enables custom CDU pages to insert keystrokes into the FMC s CDU input interface. This feature allows the custom CDU pages to manipulate the FMC as if it were a pilot.

Synchronization software for automation in anesthesia.

PubMed

Bressan, Nadja; Castro, Ana; Brás, Susana; Oliveira, Hélder P; Ribeiro, Lénio; Ferreira, David A; Antunes, Luís; Amorim, Pedro; Nunes, Catarina S

2007-01-01

This work presents the development of a software for data acquisition and control (ASYS) on a clinical setup. Similar to the industrial Supervisory Control And Data Acquisition (SCADA) the software assembles a Target Controlled Infusion (TCI) monitoring and supervisory control data in real time from devices in a surgical room. The software is not a full controller since the TCI systems comprehend permanent interaction from the anesthesiologist. Based on pharmacokinetic models, the effect-site and plasma concentrations can be related with the drug dose infused and vice versa. The software determines the infusion rates of the drug which are given as commands to the infusion pumps. This software provides the anesthesiologist with a trustworthy tool for managing a safe and balanced anesthesia. Since it also incorporates the acquisition and display of patients brain signals.

Designing Control System Application Software for Change

NASA Technical Reports Server (NTRS)

Boulanger, Richard

2001-01-01

The Unified Modeling Language (UML) was used to design the Environmental Systems Test Stand (ESTS) control system software. The UML was chosen for its ability to facilitate a clear dialog between software designer and customer, from which requirements are discovered and documented in a manner which transposes directly to program objects. Applying the UML to control system software design has resulted in a baseline set of documents from which change and effort of that change can be accurately measured. As the Environmental Systems Test Stand evolves, accurate estimates of the time and effort required to change the control system software will be made. Accurate quantification of the cost of software change can be before implementation, improving schedule and budget accuracy.

Guidance and Control Software Project Data - Volume 2: Development Documents

NASA Technical Reports Server (NTRS)

Hayhurst, Kelly J. (Editor)

2008-01-01

The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes the development documents from the GCS project. Volume 2 contains three appendices: A. Guidance and Control Software Development Specification; B. Design Description for the Pluto Implementation of the Guidance and Control Software; and C. Source Code for the Pluto Implementation of the Guidance and Control Software

Porting and refurbishment of the WSS TNG control software

NASA Astrophysics Data System (ADS)

Caproni, Alessandro; Zacchei, Andrea; Vuerli, Claudio; Pucillo, Mauro

2004-09-01

The Workstation Software Sytem (WSS) is the high level control software of the Italian Galileo Galilei Telescope settled in La Palma Canary Island developed at the beginning of '90 for HP-UX workstations. WSS may be seen as a middle layer software system that manages the communications between the real time systems (VME), different workstations and high level applications providing a uniform distributed environment. The project to port the control software from the HP workstation to Linux environment started at the end of 2001. It is aimed to refurbish the control software introducing some of the new software technologies and languages, available for free in the Linux operating system. The project was realized by gradually substituting each HP workstation with a Linux PC with the goal to avoid main changes in the original software running under HP-UX. Three main phases characterized the project: creation of a simulated control room with several Linux PCs running WSS (to check all the functionality); insertion in the simulated control room of some HPs (to check the mixed environment); substitution of HP workstation in the real control room. From a software point of view, the project introduces some new technologies, like multi-threading, and the possibility to develop high level WSS applications with almost every programming language that implements the Berkley sockets. A library to develop java applications has also been created and tested.

Software Development for EECU Platform of Turbofan Engine

NASA Astrophysics Data System (ADS)

Kim, Bo Gyoung; Kwak, Dohyup; Kim, Byunghyun; Choi, Hee ju; Kong, Changduk

2017-04-01

The turbofan engine operation consists of a number of hardware and software. The engine is controlled by Electronic Engine Control Unit (EECU). In order to control the engine, EECU communicates with an aircraft system, Actuator Drive Unit (ADU), Engine Power Unit (EPU) and sensors on the engine. This paper tried to investigate the process form starting to taking-off and aims to design the EECU software mode and defined communication data format. The software is implemented according to the designed software mode.

The Role and Quality of Software Safety in the NASA Constellation Program

NASA Technical Reports Server (NTRS)

Layman, Lucas; Basili, Victor R.; Zelkowitz, Marvin V.

2010-01-01

In this study, we examine software safety risk in the early design phase of the NASA Constellation spaceflight program. Obtaining an accurate, program-wide picture of software safety risk is difficult across multiple, independently-developing systems. We leverage one source of safety information, hazard analysis, to provide NASA quality assurance managers with information regarding the ongoing state of software safety across the program. The goal of this research is two-fold: 1) to quantify the relative importance of software with respect to system safety; and 2) to quantify the level of risk presented by software in the hazard analysis. We examined 154 hazard reports created during the preliminary design phase of three major flight hardware systems within the Constellation program. To quantify the importance of software, we collected metrics based on the number of software-related causes and controls of hazardous conditions. To quantify the level of risk presented by software, we created a metric scheme to measure the specificity of these software causes. We found that from 49-70% of hazardous conditions in the three systems could be caused by software or software was involved in the prevention of the hazardous condition. We also found that 12-17% of the 2013 hazard causes involved software, and that 23-29% of all causes had a software control. Furthermore, 10-12% of all controls were software-based. There is potential for inaccuracy in these counts, however, as software causes are not consistently scoped, and the presence of software in a cause or control is not always clear. The application of our software specificity metrics also identified risks in the hazard reporting process. In particular, we found a number of traceability risks in the hazard reports may impede verification of software and system safety.

Orbiter subsystem hardware/software interaction analysis. Volume 8: AFT reaction control system, part 2

NASA Technical Reports Server (NTRS)

Becker, D. D.

1980-01-01

The orbiter subsystems and interfacing program elements which interact with the orbiter computer flight software are analyzed. The failure modes identified in the subsystem/element failure mode and effects analysis are examined. Potential interaction with the software is examined through an evaluation of the software requirements. The analysis is restricted to flight software requirements and excludes utility/checkout software. The results of the hardware/software interaction analysis for the forward reaction control system are presented.

Experimental research control software system

NASA Astrophysics Data System (ADS)

Cohn, I. A.; Kovalenko, A. G.; Vystavkin, A. N.

2014-05-01

A software system, intended for automation of a small scale research, has been developed. The software allows one to control equipment, acquire and process data by means of simple scripts. The main purpose of that development is to increase experiment automation easiness, thus significantly reducing experimental setup automation efforts. In particular, minimal programming skills are required and supervisors have no reviewing troubles. Interactions between scripts and equipment are managed automatically, thus allowing to run multiple scripts simultaneously. Unlike well-known data acquisition commercial software systems, the control is performed by an imperative scripting language. This approach eases complex control and data acquisition algorithms implementation. A modular interface library performs interaction with external interfaces. While most widely used interfaces are already implemented, a simple framework is developed for fast implementations of new software and hardware interfaces. While the software is in continuous development with new features being implemented, it is already used in our laboratory for automation of a helium-3 cryostat control and data acquisition. The software is open source and distributed under Gnu Public License.

RTSPM: real-time Linux control software for scanning probe microscopy.

PubMed

Chandrasekhar, V; Mehta, M M

2013-01-01

Real time computer control is an essential feature of scanning probe microscopes, which have become important tools for the characterization and investigation of nanometer scale samples. Most commercial (and some open-source) scanning probe data acquisition software uses digital signal processors to handle the real time data processing and control, which adds to the expense and complexity of the control software. We describe here scan control software that uses a single computer and a data acquisition card to acquire scan data. The computer runs an open-source real time Linux kernel, which permits fast acquisition and control while maintaining a responsive graphical user interface. Images from a simulated tuning-fork based microscope as well as a standard topographical sample are also presented, showing some of the capabilities of the software.

Wall adjustment strategy software for use with the NASA Langley 0.3-meter transonic cryogenic tunnel adaptive wall test section

NASA Technical Reports Server (NTRS)

Wolf, Stephen W. D.

1988-01-01

The Wall Adjustment Strategy (WAS) software provides successful on-line control of the 2-D flexible walled test section of the Langley 0.3-m Transonic Cryogenic Tunnel. This software package allows the level of operator intervention to be regulated as necessary for research and production type 2-D testing using and Adaptive Wall Test Section (AWTS). The software is designed to accept modification for future requirements, such as 3-D testing, with a minimum of complexity. The WAS software described is an attempt to provide a user friendly package which could be used to control any flexible walled AWTS. Control system constraints influence the details of data transfer, not the data type. Then this entire software package could be used in different control systems, if suitable interface software is available. A complete overview of the software highlights the data flow paths, the modular architecture of the software and the various operating and analysis modes available. A detailed description of the software modules includes listings of the code. A user's manual is provided to explain task generation, operating environment, user options and what to expect at execution.

Modernized build and test infrastructure for control software at ESO: highly flexible building, testing, and automatic quality practices for telescope control software

NASA Astrophysics Data System (ADS)

Pellegrin, F.; Jeram, B.; Haucke, J.; Feyrin, S.

2016-07-01

The paper describes the introduction of a new automatized build and test infrastructure, based on the open-source software Jenkins1, into the ESO Very Large Telescope control software to replace the preexisting in-house solution. A brief introduction to software quality practices is given, a description of the previous solution, the limitations of it and new upcoming requirements. Modifications required to adapt the new system are described, how these were implemented to current software and the results obtained. An overview on how the new system may be used in future projects is also presented.

An empirical study of flight control software reliability

NASA Technical Reports Server (NTRS)

Dunham, J. R.; Pierce, J. L.

1986-01-01

The results of a laboratory experiment in flight control software reliability are reported. The experiment tests a small sample of implementations of a pitch axis control law for a PA28 aircraft with over 14 million pitch commands with varying levels of additive input and feedback noise. The testing which uses the method of n-version programming for error detection surfaced four software faults in one implementation of the control law. The small number of detected faults precluded the conduct of the error burst analyses. The pitch axis problem provides data for use in constructing a model in the prediction of the reliability of software in systems with feedback. The study is undertaken to find means to perform reliability evaluations of flight control software.

Flight software requirements and design support system

NASA Technical Reports Server (NTRS)

Riddle, W. E.; Edwards, B.

1980-01-01

The desirability and feasibility of computer-augmented support for the pre-implementation activities occurring during the development of flight control software was investigated. The specific topics to be investigated were the capabilities to be included in a pre-implementation support system for flight control software system development, and the specification of a preliminary design for such a system. Further, the pre-implementation support system was to be characterized and specified under the constraints that it: (1) support both description and assessment of flight control software requirements definitions and design specification; (2) account for known software description and assessment techniques; (3) be compatible with existing and planned NASA flight control software development support system; and (4) does not impose, but may encourage, specific development technologies. An overview of the results is given.

Framework Based Guidance Navigation and Control Flight Software Development

NASA Technical Reports Server (NTRS)

McComas, David

2007-01-01

This viewgraph presentation describes NASA's guidance navigation and control flight software development background. The contents include: 1) NASA/Goddard Guidance Navigation and Control (GN&C) Flight Software (FSW) Development Background; 2) GN&C FSW Development Improvement Concepts; and 3) GN&C FSW Application Framework.

NASA's Software Safety Standard

NASA Technical Reports Server (NTRS)

Ramsay, Christopher M.

2005-01-01

NASA (National Aeronautics and Space Administration) relies more and more on software to control, monitor, and verify its safety critical systems, facilities and operations. Since the 1960's there has hardly been a spacecraft (manned or unmanned) launched that did not have a computer on board that provided vital command and control services. Despite this growing dependence on software control and monitoring, there has been no consistent application of software safety practices and methodology to NASA's projects with safety critical software. Led by the NASA Headquarters Office of Safety and Mission Assurance, the NASA Software Safety Standard (STD-18l9.13B) has recently undergone a significant update in an attempt to provide that consistency. This paper will discuss the key features of the new NASA Software Safety Standard. It will start with a brief history of the use and development of software in safety critical applications at NASA. It will then give a brief overview of the NASA Software Working Group and the approach it took to revise the software engineering process across the Agency.

Modular Rocket Engine Control Software (MRECS)

NASA Technical Reports Server (NTRS)

Tarrant, Charlie; Crook, Jerry

1997-01-01

The Modular Rocket Engine Control Software (MRECS) Program is a technology demonstration effort designed to advance the state-of-the-art in launch vehicle propulsion systems. Its emphasis is on developing and demonstrating a modular software architecture for a generic, advanced engine control system that will result in lower software maintenance (operations) costs. It effectively accommodates software requirements changes that occur due to hardware. technology upgrades and engine development testing. Ground rules directed by MSFC were to optimize modularity and implement the software in the Ada programming language. MRECS system software and the software development environment utilize Commercial-Off-the-Shelf (COTS) products. This paper presents the objectives and benefits of the program. The software architecture, design, and development environment are described. MRECS tasks are defined and timing relationships given. Major accomplishment are listed. MRECS offers benefits to a wide variety of advanced technology programs in the areas of modular software, architecture, reuse software, and reduced software reverification time related to software changes. Currently, the program is focused on supporting MSFC in accomplishing a Space Shuttle Main Engine (SSME) hot-fire test at Stennis Space Center and the Low Cost Boost Technology (LCBT) Program.

Automated Transfer Vehicle (ATV) Critical Safety Software Overview

NASA Astrophysics Data System (ADS)

Berthelier, D.

2002-01-01

The European Automated Transfer Vehicle is an unmanned transportation system designed to dock to International Space Station (ISS) and to contribute to the logistic servicing of the ISS. Concisely, ATV control is realized by a nominal flight control function (using computers, softwares, sensors, actuators). In order to cover the extreme situations where this nominal chain can not ensure safe trajectory with respect to ISS, a segregated proximity flight safety function is activated, where unsafe free drift trajectories can be encountered. This function relies notably on a segregated computer, the Monitoring and Safing Unit (MSU) ; in case of major ATV malfunction detection, ATV is then controlled by MSU software. Therefore, this software is critical because a MSU software failure could result in catastrophic consequences. This paper provides an overview both of this software functions and of the software development and validation method which is specific considering its criticality. First part of the paper describes briefly the proximity flight safety chain. Second part deals with the software functions. Indeed, MSU software is in charge of monitoring nominal computers and ATV corridors, using its own navigation algorithms, and, if an abnormal situation is detected, it is in charge of the ATV control during the Collision Avoidance Manoeuvre (CAM) consisting in an attitude controlled braking boost, followed by a Post-CAM manoeuvre : a Sun-pointed ATV attitude control during up to 24 hours on a safe trajectory. Monitoring, navigation and control algorithms principles are presented. Third part of this paper describes the development and validation process : algorithms functional studies , ADA coding and unit validations ; algorithms ADA code integration and validation on a specific non real-time MATLAB/SIMULINK simulator ; global software functional engineering phase, architectural design, unit testing, integration and validation on target computer.

Real time software for a heat recovery steam generator control system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Valdes, R.; Delgadillo, M.A.; Chavez, R.

1995-12-31

This paper is addressed to the development and successful implementation of a real time software for the Heat Recovery Steam Generator (HRSG) control system of a Combined Cycle Power Plant. The real time software for the HRSG control system physically resides in a Control and Acquisition System (SAC) which is a component of a distributed control system (DCS). The SAC is a programmable controller. The DCS installed at the Gomez Palacio power plant in Mexico accomplishes the functions of logic, analog and supervisory control. The DCS is based on microprocessors and the architecture consists of workstations operating as a Man-Machinemore » Interface (MMI), linked to SAC controllers by means of a communication system. The HRSG real time software is composed of an operating system, drivers, dedicated computer program and application computer programs. The operating system used for the development of this software was the MultiTasking Operating System (MTOS). The application software developed at IIE for the HRSG control system basically consisted of a set of digital algorithms for the regulation of the main process variables at the HRSG. By using the multitasking feature of MTOS, the algorithms are executed pseudo concurrently. In this way, the applications programs continuously use the resources of the operating system to perform their functions through a uniform service interface. The application software of the HRSG consist of three tasks, each of them has dedicated responsibilities. The drivers were developed for the handling of hardware resources of the SAC controller which in turn allows the signals acquisition and data communication with a MMI. The dedicated programs were developed for hardware diagnostics, task initializations, access to the data base and fault tolerance. The application software and the dedicated software for the HRSG control system was developed using C programming language due to compactness, portability and efficiency.« less

Flexible control techniques for a lunar base

NASA Technical Reports Server (NTRS)

Kraus, Thomas W.

1992-01-01

The fundamental elements found in every terrestrial control system can be employed in all lunar applications. These elements include sensors which measure physical properties, controllers which acquire sensor data and calculate a control response, and actuators which apply the control output to the process. The unique characteristics of the lunar environment will certainly require the development of new control system technology. However, weightlessness, harsh atmospheric conditions, temperature extremes, and radiation hazards will most significantly impact the design of sensors and actuators. The controller and associated control algorithms, which are the most complex element of any control system, can be derived in their entirety from existing technology. Lunar process control applications -- ranging from small-scale research projects to full-scale processing plants -- will benefit greatly from the controller advances being developed today. In particular, new software technology aimed at commercial process monitoring and control applications will almost completely eliminate the need for custom programs and the lengthy development and testing cycle they require. The applicability of existing industrial software to lunar applications has other significant advantages in addition to cost and quality. This software is designed to run on standard hardware platforms and takes advantage of existing LAN and telecommunications technology. Further, in order to exploit the existing commercial market, the software is being designed to be implemented by users of all skill levels -- typically users who are familiar with their process, but not necessarily with software or control theory. This means that specialized technical support personnel will not need to be on-hand, and the associated costs are eliminated. Finally, the latest industrial software designed for the commercial market is extremely flexible, in order to fit the requirements of many types of processing applications with little or no customization. This means that lunar process control projects will not be delayed by unforeseen problems or last minute process modifications. The software will include all of the tools needed to adapt to virtually any changes. In contrast to other space programs which required the development of tremendous amounts of custom software, lunar-based processing facilities will benefit from the use of existing software technology which is being proven in commercial applications on Earth.

Use of Soft Computing Technologies For Rocket Engine Control

NASA Technical Reports Server (NTRS)

Trevino, Luis C.; Olcmen, Semih; Polites, Michael

2003-01-01

The problem to be addressed in this paper is to explore how the use of Soft Computing Technologies (SCT) could be employed to further improve overall engine system reliability and performance. Specifically, this will be presented by enhancing rocket engine control and engine health management (EHM) using SCT coupled with conventional control technologies, and sound software engineering practices used in Marshall s Flight Software Group. The principle goals are to improve software management, software development time and maintenance, processor execution, fault tolerance and mitigation, and nonlinear control in power level transitions. The intent is not to discuss any shortcomings of existing engine control and EHM methodologies, but to provide alternative design choices for control, EHM, implementation, performance, and sustaining engineering. The approaches outlined in this paper will require knowledge in the fields of rocket engine propulsion, software engineering for embedded systems, and soft computing technologies (i.e., neural networks, fuzzy logic, and Bayesian belief networks), much of which is presented in this paper. The first targeted demonstration rocket engine platform is the MC-1 (formerly FASTRAC Engine) which is simulated with hardware and software in the Marshall Avionics & Software Testbed laboratory that

Reconfigurable Software for Controlling Formation Flying

NASA Technical Reports Server (NTRS)

Mueller, Joseph B.

2006-01-01

Software for a system to control the trajectories of multiple spacecraft flying in formation is being developed to reflect underlying concepts of (1) a decentralized approach to guidance and control and (2) reconfigurability of the control system, including reconfigurability of the software and of control laws. The software is organized as a modular network of software tasks. The computational load for both determining relative trajectories and planning maneuvers is shared equally among all spacecraft in a cluster. The flexibility and robustness of the software are apparent in the fact that tasks can be added, removed, or replaced during flight. In a computational simulation of a representative formation-flying scenario, it was demonstrated that the following are among the services performed by the software: Uploading of commands from a ground station and distribution of the commands among the spacecraft, Autonomous initiation and reconfiguration of formations, Autonomous formation of teams through negotiations among the spacecraft, Working out details of high-level commands (e.g., shapes and sizes of geometrically complex formations), Implementation of a distributed guidance law providing autonomous optimization and assignment of target states, and Implementation of a decentralized, fuel-optimal, impulsive control law for planning maneuvers.

15 CFR 732.3 - Steps regarding the ten general prohibitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

.... The CCL and the Country Chart are taken together to define these license requirements. The applicable... 'bundled' with controlled U.S.-origin software, foreign-made software that is commingled with controlled U.S.-origin software, or foreign-made technology that is commingled with controlled U.S.-origin...

The JPL telerobot operator control station. Part 2: Software

NASA Technical Reports Server (NTRS)

Kan, Edwin P.; Landell, B. Patrick; Oxenberg, Sheldon; Morimoto, Carl

1989-01-01

The Operator Control Station of the Jet Propulsion Laboratory (JPL)/NASA Telerobot Demonstrator System provides the man-machine interface between the operator and the system. It provides all the hardware and software for accepting human input for the direct and indirect (supervised) manipulation of the robot arms and tools for task execution. Hardware and software are also provided for the display and feedback of information and control data for the operator's consumption and interaction with the task being executed. The software design of the operator control system is discussed.

A database for TMT interface control documents

NASA Astrophysics Data System (ADS)

Gillies, Kim; Roberts, Scott; Brighton, Allan; Rogers, John

2016-08-01

The TMT Software System consists of software components that interact with one another through a software infrastructure called TMT Common Software (CSW). CSW consists of software services and library code that is used by developers to create the subsystems and components that participate in the software system. CSW also defines the types of components that can be constructed and their roles. The use of common component types and shared middleware services allows standardized software interfaces for the components. A software system called the TMT Interface Database System was constructed to support the documentation of the interfaces for components based on CSW. The programmer describes a subsystem and each of its components using JSON-style text files. A command interface file describes each command a component can receive and any commands a component sends. The event interface files describe status, alarms, and events a component publishes and status and events subscribed to by a component. A web application was created to provide a user interface for the required features. Files are ingested into the software system's database. The user interface allows browsing subsystem interfaces, publishing versions of subsystem interfaces, and constructing and publishing interface control documents that consist of the intersection of two subsystem interfaces. All published subsystem interfaces and interface control documents are versioned for configuration control and follow the standard TMT change control processes. Subsystem interfaces and interface control documents can be visualized in the browser or exported as PDF files.

Trends in software reliability for digital flight control

NASA Technical Reports Server (NTRS)

Hecht, H.; Hecht, M.

1983-01-01

Software error data of major recent Digital Flight Control Systems Development Programs. The report summarizes the data, compare these data with similar data from previous surveys and identifies trends and disciplines to improve software reliability.

Modular Rocket Engine Control Software (MRECS)

NASA Technical Reports Server (NTRS)

Tarrant, C.; Crook, J.

1998-01-01

The Modular Rocket Engine Control Software (MRECS) Program is a technology demonstration effort designed to advance the state-of-the-art in launch vehicle propulsion systems. Its emphasis is on developing and demonstrating a modular software architecture for advanced engine control systems that will result in lower software maintenance (operations) costs. It effectively accommodates software requirement changes that occur due to hardware technology upgrades and engine development testing. Ground rules directed by MSFC were to optimize modularity and implement the software in the Ada programming language. MRECS system software and the software development environment utilize Commercial-Off-the-Shelf (COTS) products. This paper presents the objectives, benefits, and status of the program. The software architecture, design, and development environment are described. MRECS tasks are defined and timing relationships given. Major accomplishments are listed. MRECS offers benefits to a wide variety of advanced technology programs in the areas of modular software architecture, reuse software, and reduced software reverification time related to software changes. MRECS was recently modified to support a Space Shuttle Main Engine (SSME) hot-fire test. Cold Flow and Flight Readiness Testing were completed before the test was cancelled. Currently, the program is focused on supporting NASA MSFC in accomplishing development testing of the Fastrac Engine, part of NASA's Low Cost Technologies (LCT) Program. MRECS will be used for all engine development testing.

15 CFR 736.2 - General prohibitions and determination of applicability.

Code of Federal Regulations, 2014 CFR

2014-01-01

....-origin commodities, foreign-made commodities that are “bundled” with controlled U.S.-origin software, foreign-made software that is commingled with controlled U.S.-origin software, or foreign-made technology... of controlled U.S. content, as defined in § 734.4 of the EAR concerning the scope of the EAR. (A) It...

15 CFR 736.2 - General prohibitions and determination of applicability.

Code of Federal Regulations, 2013 CFR

2013-01-01

....-origin commodities, foreign-made commodities that are “bundled” with controlled U.S.-origin software, foreign-made software that is commingled with controlled U.S.-origin software, or foreign-made technology... of controlled U.S. content, as defined in § 734.4 of the EAR concerning the scope of the EAR. (A) It...

15 CFR 736.2 - General prohibitions and determination of applicability.

Code of Federal Regulations, 2011 CFR

2011-01-01

....-origin commodities, foreign-made commodities that are “bundled” with controlled U.S.-origin software, foreign-made software that is commingled with controlled U.S.-origin software, or foreign-made technology... of controlled U.S. content, as defined in § 734.4 of the EAR concerning the scope of the EAR. (A) It...

15 CFR 732.3 - Steps regarding the ten general prohibitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

.... The CCL and the Country Chart are taken together to define these license requirements. The applicable... commodity that is ‘bundled’ with controlled U.S.-origin software, foreign-made software that is commingled with controlled U.S.-origin software, or foreign-made technology that is commingled with controlled U.S...

Information Leaks and Limitations of Role-Based Access Control Mechanisms: A Qualitative Exploratory Single Case Study

ERIC Educational Resources Information Center

Antony, Laljith

2016-01-01

Failing to prevent leaks of confidential and proprietary information to unauthorized users from software applications is a major challenge that companies face. Access control policies defined in software applications with access control mechanisms are unable to prevent information leaks from software applications to unauthorized users. Role-based…

Instrument control software development process for the multi-star AO system ARGOS

NASA Astrophysics Data System (ADS)

Kulas, M.; Barl, L.; Borelli, J. L.; Gässler, W.; Rabien, S.

2012-09-01

The ARGOS project (Advanced Rayleigh guided Ground layer adaptive Optics System) will upgrade the Large Binocular Telescope (LBT) with an AO System consisting of six Rayleigh laser guide stars. This adaptive optics system integrates several control loops and many different components like lasers, calibration swing arms and slope computers that are dispersed throughout the telescope. The purpose of the instrument control software (ICS) is running this AO system and providing convenient client interfaces to the instruments and the control loops. The challenges for the ARGOS ICS are the development of a distributed and safety-critical software system with no defects in a short time, the creation of huge and complex software programs with a maintainable code base, the delivery of software components with the desired functionality and the support of geographically distributed project partners. To tackle these difficult tasks, the ARGOS software engineers reuse existing software like the novel middleware from LINC-NIRVANA, an instrument for the LBT, provide many tests at different functional levels like unit tests and regression tests, agree about code and architecture style and deliver software incrementally while closely collaborating with the project partners. Many ARGOS ICS components are already successfully in use in the laboratories for testing ARGOS control loops.

Software quality assurance plan for GCS

NASA Technical Reports Server (NTRS)

Duncan, Stephen E.; Bailey, Elizabeth K.

1990-01-01

The software quality assurance (SQA) function for the Guidance and Control Software (GCS) project which is part of a software error studies research program is described. The SQA plan outlines all of the procedures, controls, and audits to be carried out by the SQA organization to ensure adherence to the policies, procedures, and standards for the GCS project.

R-189 (C-620) air compressor control logic software documentation. Revision 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walter, K.E.

1995-06-08

This relates to FFTF plant air compressors. Purpose of this document is to provide an updated Computer Software Description for the software to be used on R-189 (C-620-C) air compressor programmable controllers. Logic software design changes were required to allow automatic starting of a compressor that had not been previously started.

Research on software behavior trust based on hierarchy evaluation

NASA Astrophysics Data System (ADS)

Long, Ke; Xu, Haishui

2017-08-01

In view of the correlation software behavior, we evaluate software behavior credibility from two levels of control flow and data flow. In control flow level, method of the software behavior of trace based on support vector machine (SVM) is proposed. In data flow level, behavioral evidence evaluation based on fuzzy decision analysis method is put forward.

Man-rated flight software for the F-8 DFBW program

NASA Technical Reports Server (NTRS)

Bairnsfather, R. R.

1976-01-01

The design, implementation, and verification of the flight control software used in the F-8 DFBW program are discussed. Since the DFBW utilizes an Apollo computer and hardware, the procedures, controls, and basic management techniques employed are based on those developed for the Apollo software system. Program assembly control, simulator configuration control, erasable-memory load generation, change procedures and anomaly reporting are discussed. The primary verification tools are described, as well as the program test plans and their implementation on the various simulators. Failure effects analysis and the creation of special failure generating software for testing purposes are described.

Production of Reliable Flight Crucial Software: Validation Methods Research for Fault Tolerant Avionics and Control Systems Sub-Working Group Meeting

NASA Technical Reports Server (NTRS)

Dunham, J. R. (Editor); Knight, J. C. (Editor)

1982-01-01

The state of the art in the production of crucial software for flight control applications was addressed. The association between reliability metrics and software is considered. Thirteen software development projects are discussed. A short term need for research in the areas of tool development and software fault tolerance was indicated. For the long term, research in format verification or proof methods was recommended. Formal specification and software reliability modeling, were recommended as topics for both short and long term research.

ControlShell - A real-time software framework

NASA Technical Reports Server (NTRS)

Schneider, Stanley A.; Ullman, Marc A.; Chen, Vincent W.

1991-01-01

ControlShell is designed to enable modular design and impplementation of real-time software. It is an object-oriented tool-set for real-time software system programming. It provides a series of execution and data interchange mechansims that form a framework for building real-time applications. These mechanisms allow a component-based approach to real-time software generation and mangement. By defining a set of interface specifications for intermodule interaction, ControlShell provides a common platform that is the basis for real-time code development and exchange.

Design requirements for SRB production control system. Volume 3: Package evaluation, modification and hardware

NASA Technical Reports Server (NTRS)

1981-01-01

The software package evaluation was designed to analyze commercially available, field-proven, production control or manufacturing resource planning management technology and software package. The analysis was conducted by comparing SRB production control software requirements and conceptual system design to software package capabilities. The methodology of evaluation and the findings at each stage of evaluation are described. Topics covered include: vendor listing; request for information (RFI) document; RFI response rate and quality; RFI evaluation process; and capabilities versus requirements.

Enhanced Master Controller Unit Tester

NASA Technical Reports Server (NTRS)

Benson, Patricia; Johnson, Yvette; Johnson, Brian; Williams, Philip; Burton, Geoffrey; McCoy, Anthony

2007-01-01

The Enhanced Master Controller Unit Tester (EMUT) software is a tool for development and testing of software for a master controller (MC) flight computer. The primary function of the EMUT software is to simulate interfaces between the MC computer and external analog and digital circuitry (including other computers) in a rack of equipment to be used in scientific experiments. The simulations span the range of nominal, off-nominal, and erroneous operational conditions, enabling the testing of MC software before all the equipment becomes available.

Control Software

NASA Technical Reports Server (NTRS)

1997-01-01

Real-Time Innovations, Inc. (RTI) collaborated with Ames Research Center, the Jet Propulsion Laboratory and Stanford University to leverage NASA research to produce ControlShell software. RTI is the first "graduate" of Ames Research Center's Technology Commercialization Center. The ControlShell system was used extensively on a cooperative project to enhance the capabilities of a Russian-built Marsokhod rover being evaluated for eventual flight to Mars. RTI's ControlShell is complex, real-time command and control software, capable of processing information and controlling mechanical devices. One ControlShell tool is StethoScope. As a real-time data collection and display tool, StethoScope allows a user to see how a program is running without changing its execution. RTI has successfully applied its software savvy in other arenas, such as telecommunications, networking, video editing, semiconductor manufacturing, automobile systems, and medical imaging.

Software requirements: Guidance and control software development specification

NASA Technical Reports Server (NTRS)

Withers, B. Edward; Rich, Don C.; Lowman, Douglas S.; Buckland, R. C.

1990-01-01

The software requirements for an implementation of Guidance and Control Software (GCS) are specified. The purpose of the GCS is to provide guidance and engine control to a planetary landing vehicle during its terminal descent onto a planetary surface and to communicate sensory information about that vehicle and its descent to some receiving device. The specification was developed using the structured analysis for real time system specification methodology by Hatley and Pirbhai and was based on a simulation program used to study the probability of success of the 1976 Viking Lander missions to Mars. Three versions of GCS are being generated for use in software error studies.

Using Cognitive Control in Software Defined Networking for Port Scan Detection

DTIC Science & Technology

2017-07-01

ARL-TR-8059 ● July 2017 US Army Research Laboratory Using Cognitive Control in Software-Defined Networking for Port Scan...Cognitive Control in Software-Defined Networking for Port Scan Detection by Vinod K Mishra Computational and Information Sciences Directorate, ARL...currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) July 2017 2. REPORT TYPE

A New Control System Software for SANS BATAN Spectrometer in Serpong, Indonesia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bharoto; Putra, Edy Giri Rachman

2010-06-22

The original main control system of the 36 meter small-angle neutron scattering (SANS) BATAN Spectrometer (SMARTer) has been replaced with the new ones due to the malfunction of the main computer. For that reason, a new control system software for handling all the control systems was also developed in order to put the spectrometer back in operation. The developed software is able to control the system such as rotation movement of six pinholes system, vertical movement of four neutron guide system with the total length of 16.5 m, two-directional movement of a neutron beam stopper, forward-backward movement of a 2Dmore » position sensitive detector (2D-PSD) along 16.7 m, etc. A Visual Basic language program running on Windows operating system was employed to develop the software and it can be operated by other remote computers in the local area network. All device positions and command menu are displayed graphically in the main monitor or window and each device control can be executed by clicking the control button. Those advantages are necessary required for developing a new user-friendly control system software. Finally, the new software has been tested for handling a complete SANS experiment and it works properly.« less

A New Control System Software for SANS BATAN Spectrometer in Serpong, Indonesia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bharoto,; Putra, Edy Giri Rachman

2010-06-22

The original main control system of the 36 meter small‐angle neutron scattering (SANS) BATAN Spectrometer (SMARTer) has been replaced with the new ones due to the malfunction of the main computer. For that reason, a new control system software for handling all the control systems was also developed in order to put the spectrometer back in operation. The developed software is able to control the system such as rotation movement of six pinholes system, vertical movement of four neutron guide system with the total length of 16.5 m, two‐directional movement of a neutron beam stopper, forward‐backward movement of a 2Dmore » position sensitive detector (2D‐PSD) along 16.7 m, etc. A Visual Basic language program running on Windows operating system was employed to develop the software and it can be operated by other remote computers in the local area network. All device positions and command menu are displayed graphically in the main monitor or window and each device control can be executed by clicking the control button. Those advantages are necessary required for developing a new user‐friendly control system software. Finally, the new software has been tested for handling a complete SANS experiment and it works properly.« less

SAO mission support software and data standards, version 1.0

NASA Technical Reports Server (NTRS)

Hsieh, P.

1993-01-01

This document defines the software developed by the SAO AXAF Mission Support (MS) Program and defines standards for the software development process and control of data products generated by the software. The SAO MS is tasked to develop and use software to perform a variety of functions in support of the AXAF mission. Software is developed by software engineers and scientists, and commercial off-the-shelf (COTS) software is used either directly or customized through the use of scripts to implement analysis procedures. Software controls real-time laboratory instruments, performs data archiving, displays data, and generates model predictions. Much software is used in the analysis of data to generate data products that are required by the AXAF project, for example, on-orbit mirror performance predictions or detailed characterization of the mirror reflection performance with energy.

Open core control software for surgical robots.

PubMed

Arata, Jumpei; Kozuka, Hiroaki; Kim, Hyung Wook; Takesue, Naoyuki; Vladimirov, B; Sakaguchi, Masamichi; Tokuda, Junichi; Hata, Nobuhiko; Chinzei, Kiyoyuki; Fujimoto, Hideo

2010-05-01

In these days, patients and doctors in operation room are surrounded by many medical devices as resulting from recent advancement of medical technology. However, these cutting-edge medical devices are working independently and not collaborating with each other, even though the collaborations between these devices such as navigation systems and medical imaging devices are becoming very important for accomplishing complex surgical tasks (such as a tumor removal procedure while checking the tumor location in neurosurgery). On the other hand, several surgical robots have been commercialized, and are becoming common. However, these surgical robots are not open for collaborations with external medical devices in these days. A cutting-edge "intelligent surgical robot" will be possible in collaborating with surgical robots, various kinds of sensors, navigation system and so on. On the other hand, most of the academic software developments for surgical robots are "home-made" in their research institutions and not open to the public. Therefore, open source control software for surgical robots can be beneficial in this field. From these perspectives, we developed Open Core Control software for surgical robots to overcome these challenges. In general, control softwares have hardware dependencies based on actuators, sensors and various kinds of internal devices. Therefore, these control softwares cannot be used on different types of robots without modifications. However, the structure of the Open Core Control software can be reused for various types of robots by abstracting hardware dependent parts. In addition, network connectivity is crucial for collaboration between advanced medical devices. The OpenIGTLink is adopted in Interface class which plays a role to communicate with external medical devices. At the same time, it is essential to maintain the stable operation within the asynchronous data transactions through network. In the Open Core Control software, several techniques for this purpose were introduced. Virtual fixture is well known technique as a "force guide" for supporting operators to perform precise manipulation by using a master-slave robot. The virtual fixture for precise and safety surgery was implemented on the system to demonstrate an idea of high-level collaboration between a surgical robot and a navigation system. The extension of virtual fixture is not a part of the Open Core Control system, however, the function such as virtual fixture cannot be realized without a tight collaboration between cutting-edge medical devices. By using the virtual fixture, operators can pre-define an accessible area on the navigation system, and the area information can be transferred to the robot. In this manner, the surgical console generates the reflection force when the operator tries to get out from the pre-defined accessible area during surgery. The Open Core Control software was implemented on a surgical master-slave robot and stable operation was observed in a motion test. The tip of the surgical robot was displayed on a navigation system by connecting the surgical robot with a 3D position sensor through the OpenIGTLink. The accessible area was pre-defined before the operation, and the virtual fixture was displayed as a "force guide" on the surgical console. In addition, the system showed stable performance in a duration test with network disturbance. In this paper, a design of the Open Core Control software for surgical robots and the implementation of virtual fixture were described. The Open Core Control software was implemented on a surgical robot system and showed stable performance in high-level collaboration works. The Open Core Control software is developed to be a widely used platform of surgical robots. Safety issues are essential for control software of these complex medical devices. It is important to follow the global specifications such as a FDA requirement "General Principles of Software Validation" or IEC62304. For following these regulations, it is important to develop a self-test environment. Therefore, a test environment is now under development to test various interference in operation room such as a noise of electric knife by considering safety and test environment regulations such as ISO13849 and IEC60508. The Open Core Control software is currently being developed software in open-source manner and available on the Internet. A communization of software interface is becoming a major trend in this field. Based on this perspective, the Open Core Control software can be expected to bring contributions in this field.

Software Design Improvements. Part 1; Software Benefits and Limitations

NASA Technical Reports Server (NTRS)

Lalli, Vincent R.; Packard, Michael H.; Ziemianski, Tom

1997-01-01

Computer hardware and associated software have been used for many years to process accounting information, to analyze test data and to perform engineering analysis. Now computers and software also control everything from automobiles to washing machines and the number and type of applications are growing at an exponential rate. The size of individual program has shown similar growth. Furthermore, software and hardware are used to monitor and/or control potentially dangerous products and safety-critical systems. These uses include everything from airplanes and braking systems to medical devices and nuclear plants. The question is: how can this hardware and software be made more reliable? Also, how can software quality be improved? What methodology needs to be provided on large and small software products to improve the design and how can software be verified?

Computer Software Configuration Item-Specific Flight Software Image Transfer Script Generator

NASA Technical Reports Server (NTRS)

Bolen, Kenny; Greenlaw, Ronald

2010-01-01

A K-shell UNIX script enables the International Space Station (ISS) Flight Control Team (FCT) operators in NASA s Mission Control Center (MCC) in Houston to transfer an entire or partial computer software configuration item (CSCI) from a flight software compact disk (CD) to the onboard Portable Computer System (PCS). The tool is designed to read the content stored on a flight software CD and generate individual CSCI transfer scripts that are capable of transferring the flight software content in a given subdirectory on the CD to the scratch directory on the PCS. The flight control team can then transfer the flight software from the PCS scratch directory to the Electronically Erasable Programmable Read Only Memory (EEPROM) of an ISS Multiplexer/ Demultiplexer (MDM) via the Indirect File Transfer capability. The individual CSCI scripts and the CSCI Specific Flight Software Image Transfer Script Generator (CFITSG), when executed a second time, will remove all components from their original execution. The tool will identify errors in the transfer process and create logs of the transferred software for the purposes of configuration management.

A general observatory control software framework design for existing small and mid-size telescopes

NASA Astrophysics Data System (ADS)

Ge, Liang; Lu, Xiao-Meng; Jiang, Xiao-Jun

2015-07-01

A general framework for observatory control software would help to improve the efficiency of observation and operation of telescopes, and would also be advantageous for remote and joint observations. We describe a general framework for observatory control software, which considers principles of flexibility and inheritance to meet the expectations from observers and technical personnel. This framework includes observation scheduling, device control and data storage. The design is based on a finite state machine that controls the whole process.

A Design and Development of Multi-Purpose CCD Camera System with Thermoelectric Cooling: Software

NASA Astrophysics Data System (ADS)

Oh, S. H.; Kang, Y. W.; Byun, Y. I.

2007-12-01

We present a software which we developed for the multi-purpose CCD camera. This software can be used on the all 3 types of CCD - KAF-0401E (768×512), KAF-1602E (15367times;1024), KAF-3200E (2184×1472) made in KODAK Co.. For the efficient CCD camera control, the software is operated with two independent processes of the CCD control program and the temperature/shutter operation program. This software is designed to fully automatic operation as well as manually operation under LINUX system, and is controled by LINUX user signal procedure. We plan to use this software for all sky survey system and also night sky monitoring and sky observation. As our results, the read-out time of each CCD are about 15sec, 64sec, 134sec for KAF-0401E, KAF-1602E, KAF-3200E., because these time are limited by the data transmission speed of parallel port. For larger format CCD, the data transmission is required more high speed. we are considering this control software to one using USB port for high speed data transmission.

Flight software development for the isothermal dendritic growth experiment

NASA Technical Reports Server (NTRS)

Levinson, Laurie H.; Winsa, Edward A.; Glicksman, Martin E.

1989-01-01

The Isothermal Dendritic Growth Experiment (IDGE) is a microgravity materials science experiment scheduled to fly in the cargo bay of the shuttle on the United States Microgravity Payload (USMP) carrier. The experiment will be operated by real-time control software which will not only monitor and control onboard experiment hardware, but will also communicate, via downlink data and uplink commands, with the Payload Operations Control Center (POCC) at NASA George C. Marshall Space Flight Center (MSFC). The software development approach being used to implement this system began with software functional requirements specification. This was accomplished using the Yourdon/DeMarco methodology as supplemented by the Ward/Mellor real-time extensions. The requirements specification in combination with software prototyping was then used to generate a detailed design consisting of structure charts, module prologues, and Program Design Language (PDL) specifications. This detailed design will next be used to code the software, followed finally by testing against the functional requirements. The result will be a modular real-time control software system with traceability through every phase of the development process.

Flight software development for the isothermal dendritic growth experiment

NASA Technical Reports Server (NTRS)

Levinson, Laurie H.; Winsa, Edward A.; Glicksman, M. E.

1990-01-01

The Isothermal Dendritic Growth Experiment (IDGE) is a microgravity materials science experiment scheduled to fly in the cargo bay of the shuttle on the United States Microgravity Payload (USMP) carrier. The experiment will be operated by real-time control software which will not only monitor and control onboard experiment hardware, but will also communicate, via downlink data and unlink commands, with the Payload Operations Control Center (POCC) at NASA George C. Marshall Space Flight Center (MSFC). The software development approach being used to implement this system began with software functional requirements specification. This was accomplished using the Yourdon/DeMarco methodology as supplemented by the Ward/Mellor real-time extensions. The requirements specification in combination with software prototyping was then used to generate a detailed design consisting of structure charts, module prologues, and Program Design Language (PDL) specifications. This detailed design will next be used to code the software, followed finally by testing against the functional requirements. The result will be a modular real-time control software system with traceability through every phase of the development process.

How Safe Is Control Software

NASA Technical Reports Server (NTRS)

Dunn, William R.; Corliss, Lloyd D.

1991-01-01

Paper examines issue of software safety. Presents four case histories of software-safety analysis. Concludes that, to be safe, software, for all practical purposes, must be free of errors. Backup systems still needed to prevent catastrophic software failures.

Control System Architectures, Technologies and Concepts for Near Term and Future Human Exploration of Space

NASA Technical Reports Server (NTRS)

Boulanger, Richard; Overland, David

2004-01-01

Technologies that facilitate the design and control of complex, hybrid, and resource-constrained systems are examined. This paper focuses on design methodologies, and system architectures, not on specific control methods that may be applied to life support subsystems. Honeywell and Boeing have estimated that 60-80Y0 of the effort in developing complex control systems is software development, and only 20-40% is control system development. It has also been shown that large software projects have failure rates of as high as 50-65%. Concepts discussed include the Unified Modeling Language (UML) and design patterns with the goal of creating a self-improving, self-documenting system design process. Successful architectures for control must not only facilitate hardware to software integration, but must also reconcile continuously changing software with much less frequently changing hardware. These architectures rely on software modules or components to facilitate change. Architecting such systems for change leverages the interfaces between these modules or components.

Using CONFIG for Simulation of Operation of Water Recovery Subsystems for Advanced Control Software Evaluation

NASA Technical Reports Server (NTRS)

Malin, Jane T.; Flores, Luis; Fleming, Land; Throop, Daiv

2002-01-01

A hybrid discrete/continuous simulation tool, CONFIG, has been developed to support evaluation of the operability life support systems. CON FIG simulates operations scenarios in which flows and pressures change continuously while system reconfigurations occur as discrete events. In simulations, intelligent control software can interact dynamically with hardware system models. CONFIG simulations have been used to evaluate control software and intelligent agents for automating life support systems operations. A CON FIG model of an advanced biological water recovery system has been developed to interact with intelligent control software that is being used in a water system test at NASA Johnson Space Center

ESO Demonstration Project with the NRAO 12-m Antenna

NASA Astrophysics Data System (ADS)

Heald, R.; Karban, R.

2000-03-01

During the months of September through November 1999, an ALMA joint demonstration project between the European Southern Observatory (ESO) and the National Radio Astronomy Observatory (NRAO) was carried out in Socorro/New Mexico. During this period, Robert Karban (ESO) and Ron Heald (NRAO) worked together on the ESO Demonstration Project. The project integrated ESO software and existing NRAO software (a prototype for the future ALMA control software) to control the motion of the Kitt Peak 12-m antenna. ESO software from the VLT provided the operator interface and coordinate transformation software, while Pat Wallace's TPOINT provided the pointing- model software.

Bayesian Software Health Management for Aircraft Guidance, Navigation, and Control

NASA Technical Reports Server (NTRS)

Schumann, Johann; Mbaya, Timmy; Menghoel, Ole

2011-01-01

Modern aircraft, both piloted fly-by-wire commercial aircraft as well as UAVs, more and more depend on highly complex safety critical software systems with many sensors and computer-controlled actuators. Despite careful design and V&V of the software, severe incidents have happened due to malfunctioning software. In this paper, we discuss the use of Bayesian networks (BNs) to monitor the health of the on-board software and sensor system, and to perform advanced on-board diagnostic reasoning. We will focus on the approach to develop reliable and robust health models for the combined software and sensor systems.

The Design of Software for Three-Phase Induction Motor Test System

NASA Astrophysics Data System (ADS)

Haixiang, Xu; Fengqi, Wu; Jiai, Xue

2017-11-01

The design and development of control system software is important to three-phase induction motor test equipment, which needs to be completely familiar with the test process and the control procedure of test equipment. In this paper, the software is developed according to the national standard (GB/T1032-2005) about three-phase induction motor test method by VB language. The control system and data analysis software and the implement about motor test system are described individually, which has the advantages of high automation and high accuracy.

Framework for Small-Scale Experiments in Software Engineering: Guidance and Control Software Project: Software Engineering Case Study

NASA Technical Reports Server (NTRS)

Hayhurst, Kelly J.

1998-01-01

Software is becoming increasingly significant in today's critical avionics systems. To achieve safe, reliable software, government regulatory agencies such as the Federal Aviation Administration (FAA) and the Department of Defense mandate the use of certain software development methods. However, little scientific evidence exists to show a correlation between software development methods and product quality. Given this lack of evidence, a series of experiments has been conducted to understand why and how software fails. The Guidance and Control Software (GCS) project is the latest in this series. The GCS project is a case study of the Requirements and Technical Concepts for Aviation RTCA/DO-178B guidelines, Software Considerations in Airborne Systems and Equipment Certification. All civil transport airframe and equipment vendors are expected to comply with these guidelines in building systems to be certified by the FAA for use in commercial aircraft. For the case study, two implementations of a guidance and control application were developed to comply with the DO-178B guidelines for Level A (critical) software. The development included the requirements, design, coding, verification, configuration management, and quality assurance processes. This paper discusses the details of the GCS project and presents the results of the case study.

Automated Cryocooler Monitor and Control System Software

NASA Technical Reports Server (NTRS)

Britchcliffe, Michael J.; Conroy, Bruce L.; Anderson, Paul E.; Wilson, Ahmad

2011-01-01

This software is used in an automated cryogenic control system developed to monitor and control the operation of small-scale cryocoolers. The system was designed to automate the cryogenically cooled low-noise amplifier system described in "Automated Cryocooler Monitor and Control System" (NPO-47246), NASA Tech Briefs, Vol. 35, No. 5 (May 2011), page 7a. The software contains algorithms necessary to convert non-linear output voltages from the cryogenic diode-type thermometers and vacuum pressure and helium pressure sensors, to temperature and pressure units. The control function algorithms use the monitor data to control the cooler power, vacuum solenoid, vacuum pump, and electrical warm-up heaters. The control algorithms are based on a rule-based system that activates the required device based on the operating mode. The external interface is Web-based. It acts as a Web server, providing pages for monitor, control, and configuration. No client software from the external user is required.

Software control and system configuration management - A process that works

NASA Technical Reports Server (NTRS)

Petersen, K. L.; Flores, C., Jr.

1983-01-01

A comprehensive software control and system configuration management process for flight-crucial digital control systems of advanced aircraft has been developed and refined to insure efficient flight system development and safe flight operations. Because of the highly complex interactions among the hardware, software, and system elements of state-of-the-art digital flight control system designs, a systems-wide approach to configuration control and management has been used. Specific procedures are implemented to govern discrepancy reporting and reconciliation, software and hardware change control, systems verification and validation testing, and formal documentation requirements. An active and knowledgeable configuration control board reviews and approves all flight system configuration modifications and revalidation tests. This flexible process has proved effective during the development and flight testing of several research aircraft and remotely piloted research vehicles with digital flight control systems that ranged from relatively simple to highly complex, integrated mechanizations.

Software control and system configuration management: A systems-wide approach

NASA Technical Reports Server (NTRS)

Petersen, K. L.; Flores, C., Jr.

1984-01-01

A comprehensive software control and system configuration management process for flight-crucial digital control systems of advanced aircraft has been developed and refined to insure efficient flight system development and safe flight operations. Because of the highly complex interactions among the hardware, software, and system elements of state-of-the-art digital flight control system designs, a systems-wide approach to configuration control and management has been used. Specific procedures are implemented to govern discrepancy reporting and reconciliation, software and hardware change control, systems verification and validation testing, and formal documentation requirements. An active and knowledgeable configuration control board reviews and approves all flight system configuration modifications and revalidation tests. This flexible process has proved effective during the development and flight testing of several research aircraft and remotely piloted research vehicles with digital flight control systems that ranged from relatively simple to highly complex, integrated mechanizations.

GFAST Software Demonstration

NASA Image and Video Library

2017-03-17

NASA engineers and test directors gather in Firing Room 3 in the Launch Control Center at NASA's Kennedy Space Center in Florida, to watch a demonstration of the automated command and control software for the agency's Space Launch System (SLS) and Orion spacecraft. The software is called the Ground Launch Sequencer. It will be responsible for nearly all of the launch commit criteria during the final phases of launch countdowns. The Ground and Flight Application Software Team (GFAST) demonstrated the software. It was developed by the Command, Control and Communications team in the Ground Systems Development and Operations (GSDO) Program. GSDO is helping to prepare the center for the first test flight of Orion atop the SLS on Exploration Mission 1.

OpenROCS: a software tool to control robotic observatories

NASA Astrophysics Data System (ADS)

Colomé, Josep; Sanz, Josep; Vilardell, Francesc; Ribas, Ignasi; Gil, Pere

2012-09-01

We present the Open Robotic Observatory Control System (OpenROCS), an open source software platform developed for the robotic control of telescopes. It acts as a software infrastructure that executes all the necessary processes to implement responses to the system events that appear in the routine and non-routine operations associated to data-flow and housekeeping control. The OpenROCS software design and implementation provides a high flexibility to be adapted to different observatory configurations and event-action specifications. It is based on an abstract model that is independent of the specific hardware or software and is highly configurable. Interfaces to the system components are defined in a simple manner to achieve this goal. We give a detailed description of the version 2.0 of this software, based on a modular architecture developed in PHP and XML configuration files, and using standard communication protocols to interface with applications for hardware monitoring and control, environment monitoring, scheduling of tasks, image processing and data quality control. We provide two examples of how it is used as the core element of the control system in two robotic observatories: the Joan Oró Telescope at the Montsec Astronomical Observatory (Catalonia, Spain) and the SuperWASP Qatar Telescope at the Roque de los Muchachos Observatory (Canary Islands, Spain).

The role of lectins and glycans in platelet clearance

PubMed Central

Hoffmeister, Karin M.

2015-01-01

Summary In recent years, it has become increasingly apparent that the life span of transfused platelets in circulation is regulated, at least in part, by glycan-lectin mediated mechanisms. There is clear evidence that refrigerated platelets are cleared by glycan-lectin mediated clearance mechanisms. Acute platelet cooling clusters glycoprotein (GP) Ibα receptors bearing uncovered N-acetylglucosamine (GlcNAc), and αMβ2 integrins on hepatic macrophages recognise clustered GlcNAc to rapidly clear these platelets from circulation. With prolonged refrigeration GPIbα clustering bearing uncovered galactose increases, which mediates the removal of long-term refrigerated platelets via hepatic Ashwell-Morell receptors (AMR), originally named as asialoglycoprotein receptors. In contrast, little is known about the molecular mechanisms of transfused room temperature platelet clearance. This review examines the role of glycan-lectin mediated clearance of exogenous, i.e. transfused chilled platelet clearance and briefly addresses the current knowledge of stored platelet function, degradation and its relation to platelet clearance. PMID:21781240

ARC Software and Models

Science.gov Websites

produce software code and methodologies that are transferred to TARDEC and industry partners. These constraints", ASME Dynamic Systems and Control Conference, 2013, DOI:10.1115/DSCC2013-3935 Software Monitoring",IEEE Transactions on Control Systems Technology, DOI:10.1109/TCST.2012.2217143 Fast

Using Automatic Code Generation in the Attitude Control Flight Software Engineering Process

NASA Technical Reports Server (NTRS)

McComas, David; O'Donnell, James R., Jr.; Andrews, Stephen F.

1999-01-01

This paper presents an overview of the attitude control subsystem flight software development process, identifies how the process has changed due to automatic code generation, analyzes each software development phase in detail, and concludes with a summary of our lessons learned.

Software for real-time control of a tidal liquid ventilator.

PubMed

Heckman, J L; Hoffman, J; Shaffer, T H; Wolfson, M R

1999-01-01

The purpose of this project was to develop and test computer software and control algorithms designed to operate a tidal liquid ventilator. The tests were executed on a 90-MHz Pentium PC with 16 MB RAM and a prototype liquid ventilator. The software was designed using Microsoft Visual C++ (Ver. 5.0) and the Microsoft Foundation Classes. It uses a graphic user interface, is multithreaded, runs in real time, and has a built-in simulator that facilitates user education in liquid-ventilation principles. The operator can use the software to specify ventilation parameters such as the frequency of ventilation, the tidal volume, and the inspiratory-expiratory time ratio. Commands are implemented via control of the pump speed and by setting the position of two two-way solenoid-controlled valves. Data for use in monitoring and control are gathered by analog-to-digital conversion. Control strategies are implemented to maintain lung volumes and airway pressures within desired ranges, according to limits set by the operator. Also, the software allows the operator to define the shape of the flow pulse during inspiration and expiration, and to optimize perfluorochemical liquid transfer while minimizing airway pressures and maintaining the desired tidal volume. The operator can stop flow during inspiration and expiration to measure alveolar pressures. At the end of expiration, the software stores all user commands and 30 ventilation parameters into an Excel spreadsheet for later review and analysis. Use of these software and control algorithms affords user-friendly operation of a tidal liquid ventilator while providing precise control of ventilation parameters.

The TJO-OAdM robotic observatory: OpenROCS and dome control

NASA Astrophysics Data System (ADS)

Colomé, Josep; Francisco, Xavier; Ribas, Ignasi; Casteels, Kevin; Martín, Jonatan

2010-07-01

The Telescope Joan Oró at the Montsec Astronomical Observatory (TJO - OAdM) is a small-class observatory working in completely unattended control. There are key problems to solve when a robotic control is envisaged, both on hardware and software issues. We present the OpenROCS (ROCS stands for Robotic Observatory Control System), an open source platform developed for the robotic control of the TJO - OAdM and similar astronomical observatories. It is a complex software architecture, composed of several applications for hardware control, event handling, environment monitoring, target scheduling, image reduction pipeline, etc. The code is developed in Java, C++, Python and Perl. The software infrastructure used is based on the Internet Communications Engine (Ice), an object-oriented middleware that provides object-oriented remote procedure call, grid computing, and publish/subscribe functionality. We also describe the subsystem in charge of the dome control: several hardware and software elements developed to specially protect the system at this identified single point of failure. It integrates a redundant control and a rain detector signal for alarm triggering and it responds autonomously in case communication with any of the control elements is lost (watchdog functionality). The self-developed control software suite (OpenROCS) and dome control system have proven to be highly reliable.

Architectures and Evaluation for Adjustable Control Autonomy for Space-Based Life Support Systems

NASA Technical Reports Server (NTRS)

Malin, Jane T.; Schreckenghost, Debra K.

2001-01-01

In the past five years, a number of automation applications for control of crew life support systems have been developed and evaluated in the Adjustable Autonomy Testbed at NASA's Johnson Space Center. This paper surveys progress on an adjustable autonomous control architecture for situations where software and human operators work together to manage anomalies and other system problems. When problems occur, the level of control autonomy can be adjusted, so that operators and software agents can work together on diagnosis and recovery. In 1997 adjustable autonomy software was developed to manage gas transfer and storage in a closed life support test. Four crewmembers lived and worked in a chamber for 91 days, with both air and water recycling. CO2 was converted to O2 by gas processing systems and wheat crops. With the automation software, significantly fewer hours were spent monitoring operations. System-level validation testing of the software by interactive hybrid simulation revealed problems both in software requirements and implementation. Since that time, we have been developing multi-agent approaches for automation software and human operators, to cooperatively control systems and manage problems. Each new capability has been tested and demonstrated in realistic dynamic anomaly scenarios, using the hybrid simulation tool.

Proceedings of the Workshop on Computational Aspects in the Control of Flexible Systems, part 2

NASA Technical Reports Server (NTRS)

Taylor, Lawrence W., Jr. (Compiler)

1989-01-01

The Control/Structures Integration Program, a survey of available software for control of flexible structures, computational efficiency and capability, modeling and parameter estimation, and control synthesis and optimization software are discussed.

Open Source Software and the Intellectual Commons.

ERIC Educational Resources Information Center

Dorman, David

2002-01-01

Discusses the Open Source Software method of software development and its relationship to control over information content. Topics include digital library resources; reference services; preservation; the legal and economic status of information; technical standards; access to digital data; control of information use; and copyright and patent laws.…

Computer and control applications in a vegetable processing plant

USDA-ARS?s Scientific Manuscript database

There are many advantages to the use of computers and control in food industry. Software in the food industry takes 2 forms - general purpose commercial computer software and software for specialized applications, such as drying and thermal processing of foods. Many applied simulation models for d...

Orbiter subsystem hardware/software interaction analysis. Volume 8: Forward reaction control system

NASA Technical Reports Server (NTRS)

Becker, D. D.

1980-01-01

The results of the orbiter hardware/software interaction analysis for the AFT reaction control system are presented. The interaction between hardware failure modes and software are examined in order to identify associated issues and risks. All orbiter subsystems and interfacing program elements which interact with the orbiter computer flight software are analyzed. The failure modes identified in the subsystem/element failure mode and effects analysis are discussed.

The Implementation of Satellite Attitude Control System Software Using Object Oriented Design

NASA Technical Reports Server (NTRS)

Reid, W. Mark; Hansell, William; Phillips, Tom; Anderson, Mark O.; Drury, Derek

1998-01-01

NASA established the Small Explorer (SNMX) program in 1988 to provide frequent opportunities for highly focused and relatively inexpensive space science missions. The SMEX program has produced five satellites, three of which have been successfully launched. The remaining two spacecraft are scheduled for launch within the coming year. NASA has recently developed a prototype for the next generation Small Explorer spacecraft (SMEX-Lite). This paper describes the object-oriented design (OOD) of the SMEX-Lite Attitude Control System (ACS) software. The SMEX-Lite ACS is three-axis controlled and is capable of performing sub-arc-minute pointing. This paper first describes high level requirements governing the SMEX-Lite ACS software architecture. Next, the context in which the software resides is explained. The paper describes the principles of encapsulation, inheritance, and polymorphism with respect to the implementation of an ACS software system. This paper will also discuss the design of several ACS software components. Specifically, object-oriented designs are presented for sensor data processing, attitude determination, attitude control, and failure detection. Finally, this paper will address the establishment of the ACS Foundation Class (AFC) Library. The AFC is a large software repository, requiring a minimal amount of code modifications to produce ACS software for future projects.

Implementing Software Safety in the NASA Environment

NASA Technical Reports Server (NTRS)

Wetherholt, Martha S.; Radley, Charles F.

1994-01-01

Until recently, NASA did not consider allowing computers total control of flight systems. Human operators, via hardware, have constituted the ultimate safety control. In an attempt to reduce costs, NASA has come to rely more and more heavily on computers and software to control space missions. (For example. software is now planned to control most of the operational functions of the International Space Station.) Thus the need for systematic software safety programs has become crucial for mission success. Concurrent engineering principles dictate that safety should be designed into software up front, not tested into the software after the fact. 'Cost of Quality' studies have statistics and metrics to prove the value of building quality and safety into the development cycle. Unfortunately, most software engineers are not familiar with designing for safety, and most safety engineers are not software experts. Software written to specifications which have not been safety analyzed is a major source of computer related accidents. Safer software is achieved step by step throughout the system and software life cycle. It is a process that includes requirements definition, hazard analyses, formal software inspections, safety analyses, testing, and maintenance. The greatest emphasis is placed on clearly and completely defining system and software requirements, including safety and reliability requirements. Unfortunately, development and review of requirements are the weakest link in the process. While some of the more academic methods, e.g. mathematical models, may help bring about safer software, this paper proposes the use of currently approved software methodologies, and sound software and assurance practices to show how, to a large degree, safety can be designed into software from the start. NASA's approach today is to first conduct a preliminary system hazard analysis (PHA) during the concept and planning phase of a project. This determines the overall hazard potential of the system to be built. Shortly thereafter, as the system requirements are being defined, the second iteration of hazard analyses takes place, the systems hazard analysis (SHA). During the systems requirements phase, decisions are made as to what functions of the system will be the responsibility of software. This is the most critical time to affect the safety of the software. From this point, software safety analyses as well as software engineering practices are the main focus for assuring safe software. While many of the steps proposed in this paper seem like just sound engineering practices, they are the best technical and most cost effective means to assure safe software within a safe system.

Two Mechanisms to Avoid Control Conflicts Resulting from Uncoordinated Intent

NASA Technical Reports Server (NTRS)

Mishkin, Andrew H.; Dvorak, Daniel L.; Wagner, David A.; Bennett, Matthew B.

2013-01-01

This software implements a real-time access control protocol that is intended to make all connected users aware of the presence of other connected users, and which of them is currently in control of the system. Here, "in control" means that a single user is authorized and enabled to issue instructions to the system. The software The software also implements a goal scheduling mechanism that can detect situations where plans for the operation of a target system proposed by different users overlap and interact in conflicting ways. In such situations, the system can either simply report the conflict (rejecting one goal or the entire plan), or reschedule the goals in a way that does not conflict. The access control mechanism (and associated control protocol) is unique. Other access control mechanisms are generally intended to authenticate users, or exclude unauthorized access. This software does neither, and would likely depend on having some other mechanism to support those requirements.

Advanced Transport Operating System (ATOPS) Flight Management/Flight Controls (FM/FC) software description

NASA Technical Reports Server (NTRS)

Wolverton, David A.; Dickson, Richard W.; Clinedinst, Winston C.; Slominski, Christopher J.

1993-01-01

The flight software developed for the Flight Management/Flight Controls (FM/FC) MicroVAX computer used on the Transport Systems Research Vehicle for Advanced Transport Operating Systems (ATOPS) research is described. The FM/FC software computes navigation position estimates, guidance commands, and those commands issued to the control surfaces to direct the aircraft in flight. Various modes of flight are provided for, ranging from computer assisted manual modes to fully automatic modes including automatic landing. A high-level system overview as well as a description of each software module comprising the system is provided. Digital systems diagrams are included for each major flight control component and selected flight management functions.

Application of Experimental and Quasi-Experimental Research Designs to Educational Software Evaluation.

ERIC Educational Resources Information Center

Muller, Eugene W.

1985-01-01

Develops generalizations for empirical evaluation of software based upon suitability of several research designs--pretest posttest control group, single-group pretest posttest, nonequivalent control group, time series, and regression discontinuity--to type of software being evaluated, and on circumstances under which evaluation is conducted. (MBR)

Analyzing a Mature Software Inspection Process Using Statistical Process Control (SPC)

NASA Technical Reports Server (NTRS)

Barnard, Julie; Carleton, Anita; Stamper, Darrell E. (Technical Monitor)

1999-01-01

This paper presents a cooperative effort where the Software Engineering Institute and the Space Shuttle Onboard Software Project could experiment applying Statistical Process Control (SPC) analysis to inspection activities. The topics include: 1) SPC Collaboration Overview; 2) SPC Collaboration Approach and Results; and 3) Lessons Learned.

Cloud Computing for the Grid: GridControl: A Software Platform to Support the Smart Grid

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

GENI Project: Cornell University is creating a new software platform for grid operators called GridControl that will utilize cloud computing to more efficiently control the grid. In a cloud computing system, there are minimal hardware and software demands on users. The user can tap into a network of computers that is housed elsewhere (the cloud) and the network runs computer applications for the user. The user only needs interface software to access all of the cloud’s data resources, which can be as simple as a web browser. Cloud computing can reduce costs, facilitate innovation through sharing, empower users, and improvemore » the overall reliability of a dispersed system. Cornell’s GridControl will focus on 4 elements: delivering the state of the grid to users quickly and reliably; building networked, scalable grid-control software; tailoring services to emerging smart grid uses; and simulating smart grid behavior under various conditions.« less

Design and implementation of software for automated quality control and data analysis for a complex LC/MS/MS assay for urine opiates and metabolites.

PubMed

Dickerson, Jane A; Schmeling, Michael; Hoofnagle, Andrew N; Hoffman, Noah G

2013-01-16

Mass spectrometry provides a powerful platform for performing quantitative, multiplexed assays in the clinical laboratory, but at the cost of increased complexity of analysis and quality assurance calculations compared to other methodologies. Here we describe the design and implementation of a software application that performs quality control calculations for a complex, multiplexed, mass spectrometric analysis of opioids and opioid metabolites. The development and implementation of this application improved our data analysis and quality assurance processes in several ways. First, use of the software significantly improved the procedural consistency for performing quality control calculations. Second, it reduced the amount of time technologists spent preparing and reviewing the data, saving on average over four hours per run, and in some cases improving turnaround time by a day. Third, it provides a mechanism for coupling procedural and software changes with the results of each analysis. We describe several key details of the implementation including the use of version control software and automated unit tests. These generally useful software engineering principles should be considered for any software development project in the clinical lab. Copyright © 2012 Elsevier B.V. All rights reserved.

Development of modular control software for construction 3D-printer

NASA Astrophysics Data System (ADS)

Bazhanov, A.; Yudin, D.; Porkhalo, V.

2018-03-01

This article discusses the approach to developing modular software for real-time control of an industrial construction 3D printer. The proposed structure of a two-level software solution is implemented for a robotic system that moves in a Cartesian coordinate system with multi-axis interpolation. An algorithm for the formation and analysis of a path is considered to enable the most effective control of printing through dynamic programming.

Man-rated flight software for the F-8 DFBW program

NASA Technical Reports Server (NTRS)

Bairnsfather, R. R.

1975-01-01

The design, implementation, and verification of the flight control software used in the F-8 DFBW program are discussed. Since the DFBW utilizes an Apollo computer and hardware, the procedures, controls, and basic management techniques employed are based on those developed for the Apollo software system. Program Assembly Control, simulator configuration control, erasable-memory load generation, change procedures and anomaly reporting are discussed. The primary verification tools--the all-digital simulator, the hybrid simulator, and the Iron Bird simulator--are described, as well as the program test plans and their implementation on the various simulators. Failure-effects analysis and the creation of special failure-generating software for testing purposes are described. The quality of the end product is evidenced by the F-8 DFBW flight test program in which 42 flights, totaling 58 hours of flight time, were successfully made without any DFCS inflight software, or hardware, failures.

The use of emulator-based simulators for on-board software maintenance

NASA Astrophysics Data System (ADS)

Irvine, M. M.; Dartnell, A.

2002-07-01

Traditionally, onboard software maintenance activities within the space sector are performed using hardware-based facilities. These facilities are developed around the use of hardware emulation or breadboards containing target processors. Some sort of environment is provided around the hardware to support the maintenance actives. However, these environments are not easy to use to set-up the required test scenarios, particularly when the onboard software executes in a dynamic I/O environment, e.g. attitude control software, or data handling software. In addition, the hardware and/or environment may not support the test set-up required during investigations into software anomalies, e.g. raise spurious interrupt, fail memory, etc, and the overall "visibility" of the software executing may be limited. The Software Maintenance Simulator (SOMSIM) is a tool that can support the traditional maintenance facilities. The following list contains some of the main benefits that SOMSIM can provide: Low cost flexible extension to existing product - operational simulator containing software processor emulator; System-level high-fidelity test-bed in which software "executes"; Provides a high degree of control/configuration over the entire "system", including contingency conditions perhaps not possible with real hardware; High visibility and control over execution of emulated software. This paper describes the SOMSIM concept in more detail, and also describes the SOMSIM study being carried out for ESA/ESOC by VEGA IT GmbH.

48 CFR 227.7205 - Contracts for special works.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Computer Software and Computer Software Documentation 227.7205 Contracts for special works. (a) Use the... a specific need to control the distribution of computer software or computer software documentation..., modification, reproduction, release, performance, display, or disclosure of such software or documentation. Use...

48 CFR 227.7205 - Contracts for special works.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Computer Software and Computer Software Documentation 227.7205 Contracts for special works. (a) Use the... a specific need to control the distribution of computer software or computer software documentation..., modification, reproduction, release, performance, display, or disclosure of such software or documentation. Use...

Software Configuration Management Plan for the B-Plant Canyon Ventilation Control System

DOE Office of Scientific and Technical Information (OSTI.GOV)

MCDANIEL, K.S.

1999-08-31

Project W-059 installed a new B Plant Canyon Ventilation System. Monitoring and control of the system is implemented by the Canyon Ventilation Control System (CVCS). This Software Configuration Management Plan provides instructions for change control of the CVCS.

Open core control software for surgical robots

PubMed Central

Kozuka, Hiroaki; Kim, Hyung Wook; Takesue, Naoyuki; Vladimirov, B.; Sakaguchi, Masamichi; Tokuda, Junichi; Hata, Nobuhiko; Chinzei, Kiyoyuki; Fujimoto, Hideo

2010-01-01

Object In these days, patients and doctors in operation room are surrounded by many medical devices as resulting from recent advancement of medical technology. However, these cutting-edge medical devices are working independently and not collaborating with each other, even though the collaborations between these devices such as navigation systems and medical imaging devices are becoming very important for accomplishing complex surgical tasks (such as a tumor removal procedure while checking the tumor location in neurosurgery). On the other hand, several surgical robots have been commercialized, and are becoming common. However, these surgical robots are not open for collaborations with external medical devices in these days. A cutting-edge “intelligent surgical robot” will be possible in collaborating with surgical robots, various kinds of sensors, navigation system and so on. On the other hand, most of the academic software developments for surgical robots are “home-made” in their research institutions and not open to the public. Therefore, open source control software for surgical robots can be beneficial in this field. From these perspectives, we developed Open Core Control software for surgical robots to overcome these challenges. Materials and methods In general, control softwares have hardware dependencies based on actuators, sensors and various kinds of internal devices. Therefore, these control softwares cannot be used on different types of robots without modifications. However, the structure of the Open Core Control software can be reused for various types of robots by abstracting hardware dependent parts. In addition, network connectivity is crucial for collaboration between advanced medical devices. The OpenIGTLink is adopted in Interface class which plays a role to communicate with external medical devices. At the same time, it is essential to maintain the stable operation within the asynchronous data transactions through network. In the Open Core Control software, several techniques for this purpose were introduced. Virtual fixture is well known technique as a “force guide” for supporting operators to perform precise manipulation by using a master–slave robot. The virtual fixture for precise and safety surgery was implemented on the system to demonstrate an idea of high-level collaboration between a surgical robot and a navigation system. The extension of virtual fixture is not a part of the Open Core Control system, however, the function such as virtual fixture cannot be realized without a tight collaboration between cutting-edge medical devices. By using the virtual fixture, operators can pre-define an accessible area on the navigation system, and the area information can be transferred to the robot. In this manner, the surgical console generates the reflection force when the operator tries to get out from the pre-defined accessible area during surgery. Results The Open Core Control software was implemented on a surgical master–slave robot and stable operation was observed in a motion test. The tip of the surgical robot was displayed on a navigation system by connecting the surgical robot with a 3D position sensor through the OpenIGTLink. The accessible area was pre-defined before the operation, and the virtual fixture was displayed as a “force guide” on the surgical console. In addition, the system showed stable performance in a duration test with network disturbance. Conclusion In this paper, a design of the Open Core Control software for surgical robots and the implementation of virtual fixture were described. The Open Core Control software was implemented on a surgical robot system and showed stable performance in high-level collaboration works. The Open Core Control software is developed to be a widely used platform of surgical robots. Safety issues are essential for control software of these complex medical devices. It is important to follow the global specifications such as a FDA requirement “General Principles of Software Validation” or IEC62304. For following these regulations, it is important to develop a self-test environment. Therefore, a test environment is now under development to test various interference in operation room such as a noise of electric knife by considering safety and test environment regulations such as ISO13849 and IEC60508. The Open Core Control software is currently being developed software in open-source manner and available on the Internet. A communization of software interface is becoming a major trend in this field. Based on this perspective, the Open Core Control software can be expected to bring contributions in this field. PMID:20033506

Automatic sample changer control software for automation of neutron activation analysis process in Malaysian Nuclear Agency

NASA Astrophysics Data System (ADS)

Yussup, N.; Ibrahim, M. M.; Rahman, N. A. A.; Mokhtar, M.; Salim, N. A. A.; Soh@Shaari, S. C.; Azman, A.; Lombigit, L.; Azman, A.; Omar, S. A.

2018-01-01

Most of the procedures in neutron activation analysis (NAA) process that has been established in Malaysian Nuclear Agency (Nuclear Malaysia) since 1980s were performed manually. These manual procedures carried out by the NAA laboratory personnel are time consuming and inefficient especially for sample counting and measurement process. The sample needs to be changed and the measurement software needs to be setup for every one hour counting time. Both of these procedures are performed manually for every sample. Hence, an automatic sample changer system (ASC) that consists of hardware and software is developed to automate sample counting process for up to 30 samples consecutively. This paper describes the ASC control software for NAA process which is designed and developed to control the ASC hardware and call GammaVision software for sample measurement. The software is developed by using National Instrument LabVIEW development package.

A Model-Driven Co-Design Framework for Fusing Control and Scheduling Viewpoints.

PubMed

Sundharam, Sakthivel Manikandan; Navet, Nicolas; Altmeyer, Sebastian; Havet, Lionel

2018-02-20

Model-Driven Engineering (MDE) is widely applied in the industry to develop new software functions and integrate them into the existing run-time environment of a Cyber-Physical System (CPS). The design of a software component involves designers from various viewpoints such as control theory, software engineering, safety, etc. In practice, while a designer from one discipline focuses on the core aspects of his field (for instance, a control engineer concentrates on designing a stable controller), he neglects or considers less importantly the other engineering aspects (for instance, real-time software engineering or energy efficiency). This may cause some of the functional and non-functional requirements not to be met satisfactorily. In this work, we present a co-design framework based on timing tolerance contract to address such design gaps between control and real-time software engineering. The framework consists of three steps: controller design, verified by jitter margin analysis along with co-simulation, software design verified by a novel schedulability analysis, and the run-time verification by monitoring the execution of the models on target. This framework builds on CPAL (Cyber-Physical Action Language), an MDE design environment based on model-interpretation, which enforces a timing-realistic behavior in simulation through timing and scheduling annotations. The application of our framework is exemplified in the design of an automotive cruise control system.

Control and Information Systems for the National Ignition Facility

DOE PAGES

Brunton, Gordon; Casey, Allan; Christensen, Marvin; ...

2017-03-23

Orchestration of every National Ignition Facility (NIF) shot cycle is managed by the Integrated Computer Control System (ICCS), which uses a scalable software architecture running code on more than 1950 front-end processors, embedded controllers, and supervisory servers. The ICCS operates laser and industrial control hardware containing 66 000 control and monitor points to ensure that all of NIF’s laser beams arrive at the target within 30 ps of each other and are aligned to a pointing accuracy of less than 50 μm root-mean-square, while ensuring that a host of diagnostic instruments record data in a few billionths of a second.more » NIF’s automated control subsystems are built from a common object-oriented software framework that distributes the software across the computer network and achieves interoperation between different software languages and target architectures. A large suite of business and scientific software tools supports experimental planning, experimental setup, facility configuration, and post-shot analysis. Standard business services using open-source software, commercial workflow tools, and database and messaging technologies have been developed. An information technology infrastructure consisting of servers, network devices, and storage provides the foundation for these systems. Thus, this work is an overview of the control and information systems used to support a wide variety of experiments during the National Ignition Campaign.« less

Control and Information Systems for the National Ignition Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brunton, Gordon; Casey, Allan; Christensen, Marvin

Orchestration of every National Ignition Facility (NIF) shot cycle is managed by the Integrated Computer Control System (ICCS), which uses a scalable software architecture running code on more than 1950 front-end processors, embedded controllers, and supervisory servers. The ICCS operates laser and industrial control hardware containing 66 000 control and monitor points to ensure that all of NIF’s laser beams arrive at the target within 30 ps of each other and are aligned to a pointing accuracy of less than 50 μm root-mean-square, while ensuring that a host of diagnostic instruments record data in a few billionths of a second.more » NIF’s automated control subsystems are built from a common object-oriented software framework that distributes the software across the computer network and achieves interoperation between different software languages and target architectures. A large suite of business and scientific software tools supports experimental planning, experimental setup, facility configuration, and post-shot analysis. Standard business services using open-source software, commercial workflow tools, and database and messaging technologies have been developed. An information technology infrastructure consisting of servers, network devices, and storage provides the foundation for these systems. Thus, this work is an overview of the control and information systems used to support a wide variety of experiments during the National Ignition Campaign.« less

A Model-Driven Co-Design Framework for Fusing Control and Scheduling Viewpoints

PubMed Central

Navet, Nicolas; Havet, Lionel

2018-01-01

Model-Driven Engineering (MDE) is widely applied in the industry to develop new software functions and integrate them into the existing run-time environment of a Cyber-Physical System (CPS). The design of a software component involves designers from various viewpoints such as control theory, software engineering, safety, etc. In practice, while a designer from one discipline focuses on the core aspects of his field (for instance, a control engineer concentrates on designing a stable controller), he neglects or considers less importantly the other engineering aspects (for instance, real-time software engineering or energy efficiency). This may cause some of the functional and non-functional requirements not to be met satisfactorily. In this work, we present a co-design framework based on timing tolerance contract to address such design gaps between control and real-time software engineering. The framework consists of three steps: controller design, verified by jitter margin analysis along with co-simulation, software design verified by a novel schedulability analysis, and the run-time verification by monitoring the execution of the models on target. This framework builds on CPAL (Cyber-Physical Action Language), an MDE design environment based on model-interpretation, which enforces a timing-realistic behavior in simulation through timing and scheduling annotations. The application of our framework is exemplified in the design of an automotive cruise control system. PMID:29461489

SAGA: A project to automate the management of software production systems

NASA Technical Reports Server (NTRS)

Campbell, Roy H.; Laliberte, D.; Render, H.; Sum, R.; Smith, W.; Terwilliger, R.

1987-01-01

The Software Automation, Generation and Administration (SAGA) project is investigating the design and construction of practical software engineering environments for developing and maintaining aerospace systems and applications software. The research includes the practical organization of the software lifecycle, configuration management, software requirements specifications, executable specifications, design methodologies, programming, verification, validation and testing, version control, maintenance, the reuse of software, software libraries, documentation, and automated management.

7 CFR 400.202 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... and software, data communications hardware and software, and printers utilized with the system. (e...), International Business Systems (IBM)-defined, byte controlled communications protocol, using control characters...

7 CFR 400.202 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... and software, data communications hardware and software, and printers utilized with the system. (e...), International Business Systems (IBM)-defined, byte controlled communications protocol, using control characters...

Modeling SMAP Spacecraft Attitude Control Estimation Error Using Signal Generation Model

NASA Technical Reports Server (NTRS)

Rizvi, Farheen

2016-01-01

Two ground simulation software are used to model the SMAP spacecraft dynamics. The CAST software uses a higher fidelity model than the ADAMS software. The ADAMS software models the spacecraft plant, controller and actuator models, and assumes a perfect sensor and estimator model. In this simulation study, the spacecraft dynamics results from the ADAMS software are used as CAST software is unavailable. The main source of spacecraft dynamics error in the higher fidelity CAST software is due to the estimation error. A signal generation model is developed to capture the effect of this estimation error in the overall spacecraft dynamics. Then, this signal generation model is included in the ADAMS software spacecraft dynamics estimate such that the results are similar to CAST. This signal generation model has similar characteristics mean, variance and power spectral density as the true CAST estimation error. In this way, ADAMS software can still be used while capturing the higher fidelity spacecraft dynamics modeling from CAST software.

Taking advantage of ground data systems attributes to achieve quality results in testing software

NASA Technical Reports Server (NTRS)

Sigman, Clayton B.; Koslosky, John T.; Hageman, Barbara H.

1994-01-01

During the software development life cycle process, basic testing starts with the development team. At the end of the development process, an acceptance test is performed for the user to ensure that the deliverable is acceptable. Ideally, the delivery is an operational product with zero defects. However, the goal of zero defects is normally not achieved but is successful to various degrees. With the emphasis on building low cost ground support systems while maintaining a quality product, a key element in the test process is simulator capability. This paper reviews the Transportable Payload Operations Control Center (TPOCC) Advanced Spacecraft Simulator (TASS) test tool that is used in the acceptance test process for unmanned satellite operations control centers. The TASS is designed to support the development, test and operational environments of the Goddard Space Flight Center (GSFC) operations control centers. The TASS uses the same basic architecture as the operations control center. This architecture is characterized by its use of distributed processing, industry standards, commercial off-the-shelf (COTS) hardware and software components, and reusable software. The TASS uses much of the same TPOCC architecture and reusable software that the operations control center developer uses. The TASS also makes use of reusable simulator software in the mission specific versions of the TASS. Very little new software needs to be developed, mainly mission specific telemetry communication and command processing software. By taking advantage of the ground data system attributes, successful software reuse for operational systems provides the opportunity to extend the reuse concept into the test area. Consistency in test approach is a major step in achieving quality results.

Equatorial Precession in the Control Software of the Ka-Band Object Observation and Monitoring Experiment

NASA Technical Reports Server (NTRS)

Jakeman, Hali L.

2013-01-01

The Ka-Band Object Observation and Monitoring, or KaBOOM, project is designed mainly to track and characterize near Earth objects. However, a smaller goal of the project would be to monitor pulsars and study their radio frequency signals for use as a clock in interstellar travel. The use of pulsars and their timing accuracy has been studied for decades, but never in the Ka-band of the radio frequency spectrum. In order to begin the use of KaBOOM for this research, the control systems need to be analyzed to ensure its capability. Flaws in the control documentation leave it unclear as to whether the control software processes coordinates from the J200 epoch. This experiment will examine the control software of the Intertronic 12m antennas used for the KaBOOM project and detail its capabilities in its "equatorial mode." The antennas will be pointed at 4 chosen points in the sky on several days while probing the virtual azimuth and elevation (horizon coordinate) registers. The input right ascension and declination coordinates will then be converted separately from the control software to horizontal coordinates and compared, thus determining the ability of the control software to process equatorial coordinates.

Development of Hardware-in-the-Loop Simulation Based on Gazebo and Pixhawk for Unmanned Aerial Vehicles

NASA Astrophysics Data System (ADS)

Nguyen, Khoa Dang; Ha, Cheolkeun

2018-04-01

Hardware-in-the-loop simulation (HILS) is well known as an effective approach in the design of unmanned aerial vehicles (UAV) systems, enabling engineers to test the control algorithm on a hardware board with a UAV model on the software. Performance of HILS is determined by performances of the control algorithm, the developed model, and the signal transfer between the hardware and software. The result of HILS is degraded if any signal could not be transferred to the correct destination. Therefore, this paper aims to develop a middleware software to secure communications in HILS system for testing the operation of a quad-rotor UAV. In our HILS, the Gazebo software is used to generate a nonlinear six-degrees-of-freedom (6DOF) model, sensor model, and 3D visualization for the quad-rotor UAV. Meanwhile, the flight control algorithm is designed and implemented on the Pixhawk hardware. New middleware software, referred to as the control application software (CAS), is proposed to ensure the connection and data transfer between Gazebo and Pixhawk using the multithread structure in Qt Creator. The CAS provides a graphical user interface (GUI), allowing the user to monitor the status of packet transfer, and perform the flight control commands and the real-time tuning parameters for the quad-rotor UAV. Numerical implementations have been performed to prove the effectiveness of the middleware software CAS suggested in this paper.

A universal six-joint robot controller

NASA Technical Reports Server (NTRS)

Bihn, D. G.; Hsia, T. C.

1987-01-01

A general purpose six-axis robotic manipulator controller was designed and implemented to serve as a research tool for the investigation of the practical and theoretical aspects of various control strategies in robotics. A 80286-based Intel System 310 running the Xenix operating servo software as well as the higher level software (e.g., kinematics and path planning) were employed. A Multibus compatible interface board was designed and constructed to handle I/O signals from the robot manipulator's joint motors. From the design point of view, the universal controller is capable of driving robot manipulators equipped with D.C. joint motors and position optical encoders. To test its functionality, the controller is connected to the joint motor D.C. power amplifier of a PUMA 560 arm bypassing completely the manufacturer-supplied Unimation controller. A controller algorithm consisting of local PD control laws was written and installed into the Xenix operating system. Additional software drivers were implemented to allow application programs access to the interface board. All software was written in the C language.

Development of advanced fermentor control applications for use in an industrial automation environment.

PubMed

Hamilton, Ryan; Tamminana, Krishna; Boyd, John; Sasaki, Gen; Toda, Alex; Haskell, Sid; Danbe, Elizabeth

2013-04-01

We present a software platform developed by Genentech and MathWorks Consulting Group that allows arbitrary MATLAB (MATLAB is a registered trademark of The MathWorks, Inc.) functions to perform supervisory control of process equipment (in this case, fermentors) via the OLE for process control (OPC) communication protocol, under the direction of an industrial automation layer. The software features automated synchronization and deployment of server control code and has been proven to be tolerant of OPC communication interruptions. Since deployment in the spring of 2010, this software has successfully performed supervisory control of more than 700 microbial fermentations in the Genentech pilot plant and has enabled significant reductions in the time required to develop and implement novel control strategies (months reduced to days). The software is available for download at the MathWorks File Exchange Web site at http://www.mathworks.com/matlabcentral/fileexchange/36866.

15 CFR 734.4 - De minimis U.S. content.

Code of Federal Regulations, 2010 CFR

2010-01-01

... requirements of this paragraph. (1) The U.S. origin commodities or software, if controlled under ECCNs 5A002.a...-made commodity incorporating controlled U.S.-origin commodities or “bundled” with U.S.-origin software....S.-origin software is not eligible for the de minimis exclusion and is subject to the EAR when...

15 CFR 734.4 - De minimis U.S. content.

Code of Federal Regulations, 2013 CFR

2013-01-01

... requirements of this paragraph. (1) The U.S. origin commodities or software, if controlled under ECCNs 5A002.a...-made commodity incorporating controlled U.S.-origin commodities or “bundled” with U.S.-origin software....S.-origin software is not eligible for the de minimis exclusion and is subject to the EAR when...

15 CFR 734.4 - De minimis U.S. content.

Code of Federal Regulations, 2012 CFR

2012-01-01

... requirements of this paragraph. (1) The U.S. origin commodities or software, if controlled under ECCNs 5A002.a...-made commodity incorporating controlled U.S.-origin commodities or “bundled” with U.S.-origin software....S.-origin software is not eligible for the de minimis exclusion and is subject to the EAR when...

Experience with Ada on the F-18 High Alpha Research Vehicle Flight Test Program

NASA Technical Reports Server (NTRS)

Regenie, Victoria A.; Earls, Michael; Le, Jeanette; Thomson, Michael

1992-01-01

Considerable experience was acquired with Ada at the NASA Dryden Flight Research Facility during the on-going High Alpha Technology Program. In this program, an F-18 aircraft was highly modified by the addition of thrust-vectoring vanes to the airframe. In addition, substantial alteration was made in the original quadruplex flight control system. The result is the High Alpha Research Vehicle. An additional research flight control computer was incorporated in each of the four channels. Software for the research flight control computer was written in Ada. To date, six releases of this software have been flown. This paper provides a detailed description of the modifications to the research flight control system. Efficient ground-testing of the software was accomplished by using simulations that used the Ada for portions of their software. These simulations are also described. Modifying and transferring the Ada for flight software to the software simulation configuration has allowed evaluation of this language. This paper also discusses such significant issues in using Ada as portability, modifiability, and testability as well as documentation requirements.

Experience with Ada on the F-18 High Alpha Research Vehicle flight test program

NASA Technical Reports Server (NTRS)

Regenie, Victoria A.; Earls, Michael; Le, Jeanette; Thomson, Michael

1994-01-01

Considerable experience has been acquired with Ada at the NASA Dryden Flight Research Facility during the on-going High Alpha Technology Program. In this program, an F-18 aircraft has been highly modified by the addition of thrust-vectoring vanes to the airframe. In addition, substantial alteration was made in the original quadruplex flight control system. The result is the High Alpha Research Vehicle. An additional research flight control computer was incorporated in each of the four channels. Software for the research flight control computer was written Ada. To date, six releases of this software have been flown. This paper provides a detailed description of the modifications to the research flight control system. Efficient ground-testing of the software was accomplished by using simulations that used the Ada for portions of their software. These simulations are also described. Modifying and transferring the Ada flight software to the software simulation configuration has allowed evaluation of this language. This paper also discusses such significant issues in using Ada as portability, modifiability, and testability as well as documentation requirements.

Atmosphere Explorer control system software (version 1.0)

NASA Technical Reports Server (NTRS)

Villasenor, A.

1972-01-01

The basic design is described of the Atmosphere Explorer Control System (AECS) software used in the testing, integration, and flight contol of the AE spacecraft and experiments. The software performs several vital functions, such as issuing commands to the spacecraft and experiments, receiving and processing telemetry data, and allowing for extensive data processing by experiment analysis programs. The major processing sections are: executive control section, telemetry decommutation section, command generation section, and utility section.

Transportable Payload Operations Control Center reusable software: Building blocks for quality ground data systems

NASA Technical Reports Server (NTRS)

Mahmot, Ron; Koslosky, John T.; Beach, Edward; Schwarz, Barbara

1994-01-01

The Mission Operations Division (MOD) at Goddard Space Flight Center builds Mission Operations Centers which are used by Flight Operations Teams to monitor and control satellites. Reducing system life cycle costs through software reuse has always been a priority of the MOD. The MOD's Transportable Payload Operations Control Center development team established an extensive library of 14 subsystems with over 100,000 delivered source instructions of reusable, generic software components. Nine TPOCC-based control centers to date support 11 satellites and achieved an average software reuse level of more than 75 percent. This paper shares experiences of how the TPOCC building blocks were developed and how building block developer's, mission development teams, and users are all part of the process.

Automation software for a materials testing laboratory

NASA Technical Reports Server (NTRS)

Mcgaw, Michael A.; Bonacuse, Peter J.

1990-01-01

The software environment in use at the NASA-Lewis Research Center's High Temperature Fatigue and Structures Laboratory is reviewed. This software environment is aimed at supporting the tasks involved in performing materials behavior research. The features and capabilities of the approach to specifying a materials test include static and dynamic control mode switching, enabling multimode test control; dynamic alteration of the control waveform based upon events occurring in the response variables; precise control over the nature of both command waveform generation and data acquisition; and the nesting of waveform/data acquisition strategies so that material history dependencies may be explored. To eliminate repetitive tasks in the coventional research process, a communications network software system is established which provides file interchange and remote console capabilities.

Master Pump Shutdown MPS Software Quality Assurance Plan (SQAP)

DOE Office of Scientific and Technical Information (OSTI.GOV)

BEVINS, R.R.

2000-09-20

The MPSS Software Quality Assurance (SQAP) describes the tools and strategy used in the development of the MPSS software. The document also describes the methodology for controlling and managing changes to the software.

Evaluation of power control concepts using the PMAD systems test bed. [Power Management and Distribution

NASA Technical Reports Server (NTRS)

Beach, R. F.; Kimnach, G. L.; Jett, T. A.; Trash, L. M.

1989-01-01

The Lewis Research Center's Power Management and Distribution (PMAD) System testbed and its use in the evaluation of control concepts applicable to the NASA Space Station Freedom electric power system (EPS) are described. The facility was constructed to allow testing of control hardware and software in an environment functionally similar to the space station electric power system. Control hardware and software have been developed to allow operation of the testbed power system in a manner similar to a supervisory control and data acquisition (SCADA) system employed by utility power systems for control. The system hardware and software are described.

GFAST Software Demonstration

NASA Image and Video Library

2017-03-17

NASA engineers and test directors gather in Firing Room 3 in the Launch Control Center at NASA's Kennedy Space Center in Florida, to watch a demonstration of the automated command and control software for the agency's Space Launch System (SLS) and Orion spacecraft. In front, far right, is Charlie Blackwell-Thompson, launch director for Exploration Mission 1 (EM-1). The software is called the Ground Launch Sequencer. It will be responsible for nearly all of the launch commit criteria during the final phases of launch countdowns. The Ground and Flight Application Software Team (GFAST) demonstrated the software. It was developed by the Command, Control and Communications team in the Ground Systems Development and Operations (GSDO) Program. GSDO is helping to prepare the center for the first test flight of Orion atop the SLS on EM-1.

Design and implementation of Skype USB user gateway software

NASA Astrophysics Data System (ADS)

Qi, Yang

2017-08-01

With the widespread application of VoIP, the client with private protocol becomes more and more popular. Skype is one of the representatives. How to connect Skype with PSTN just by Skype client has gradually become hot. This paper design and implement the software based on a kind of USB User Gateway. With the software Skype user can freely communicate with PSTN phone. FSM is designed as the core of the software, and Skype control is separated by the USB Gateway control. In this way, the communication becomes more flexible and efficient. In the actual user testing, the software obtains good results.

Autonomous robot software development using simple software components

NASA Astrophysics Data System (ADS)

Burke, Thomas M.; Chung, Chan-Jin

2004-10-01

Developing software to control a sophisticated lane-following, obstacle-avoiding, autonomous robot can be demanding and beyond the capabilities of novice programmers - but it doesn"t have to be. A creative software design utilizing only basic image processing and a little algebra, has been employed to control the LTU-AISSIG autonomous robot - a contestant in the 2004 Intelligent Ground Vehicle Competition (IGVC). This paper presents a software design equivalent to that used during the IGVC, but with much of the complexity removed. The result is an autonomous robot software design, that is robust, reliable, and can be implemented by programmers with a limited understanding of image processing. This design provides a solid basis for further work in autonomous robot software, as well as an interesting and achievable robotics project for students.

A Digital Control Algorithm for Magnetic Suspension Systems

NASA Technical Reports Server (NTRS)

Britton, Thomas C.

1996-01-01

An ongoing program exists to investigate and develop magnetic suspension technologies and modelling techniques at NASA Langley Research Center. Presently, there is a laboratory-scale large air-gap suspension system capable of five degree-of-freedom (DOF) control that is operational and a six DOF system that is under development. Those systems levitate a cylindrical element containing a permanent magnet core above a planar array of electromagnets, which are used for levitation and control purposes. In order to evaluate various control approaches with those systems, the Generic Real-Time State-Space Controller (GRTSSC) software package was developed. That control software package allows the user to implement multiple control methods and allows for varied input/output commands. The development of the control algorithm is presented. The desired functionality of the software is discussed, including the ability to inject noise on sensor inputs and/or actuator outputs. Various limitations, common issues, and trade-offs are discussed including data format precision; the drawbacks of using either Direct Memory Access (DMA), interrupts, or program control techniques for data acquisition; and platform dependent concerns related to the portability of the software, such as memory addressing formats. Efforts to minimize overall controller loop-rate and a comparison of achievable controller sample rates are discussed. The implementation of a modular code structure is presented. The format for the controller input data file and the noise information file is presented. Controller input vector information is available for post-processing by mathematical analysis software such as MATLAB1.

Proceedings of the Workshop on Computational Aspects in the Control of Flexible Systems, part 1

NASA Technical Reports Server (NTRS)

Taylor, Lawrence W., Jr. (Compiler)

1989-01-01

Control/Structures Integration program software needs, computer aided control engineering for flexible spacecraft, computer aided design, computational efficiency and capability, modeling and parameter estimation, and control synthesis and optimization software for flexible structures and robots are among the topics discussed.

The Implications of Using Integrated Software Support Environment for Design of Guidance and Control Systems Software

DTIC Science & Technology

1990-02-01

inspections are performed before each formal review of each software life cycle phase. * Required software audits are performed . " The software is acceptable... Audits : Software audits are performed bySQA consistent with thegeneral audit rules and an auditreportis prepared. Software Quality Inspection (SQI...DSD Software Development Method 3-34 DEFINITION OF ACRONYMS Acronym Full Name or Description MACH Methode d’Analyse et de Conception Flierarchisee

Design and reliability analysis of DP-3 dynamic positioning control architecture

NASA Astrophysics Data System (ADS)

Wang, Fang; Wan, Lei; Jiang, Da-Peng; Xu, Yu-Ru

2011-12-01

As the exploration and exploitation of oil and gas proliferate throughout deepwater area, the requirements on the reliability of dynamic positioning system become increasingly stringent. The control objective ensuring safety operation at deep water will not be met by a single controller for dynamic positioning. In order to increase the availability and reliability of dynamic positioning control system, the triple redundancy hardware and software control architectures were designed and developed according to the safe specifications of DP-3 classification notation for dynamically positioned ships and rigs. The hardware redundant configuration takes the form of triple-redundant hot standby configuration including three identical operator stations and three real-time control computers which connect each other through dual networks. The function of motion control and redundancy management of control computers were implemented by software on the real-time operating system VxWorks. The software realization of task loose synchronization, majority voting and fault detection were presented in details. A hierarchical software architecture was planed during the development of software, consisting of application layer, real-time layer and physical layer. The behavior of the DP-3 dynamic positioning control system was modeled by a Markov model to analyze its reliability. The effects of variation in parameters on the reliability measures were investigated. The time domain dynamic simulation was carried out on a deepwater drilling rig to prove the feasibility of the proposed control architecture.

Software framework for the upcoming MMT Observatory primary mirror re-aluminization

NASA Astrophysics Data System (ADS)

Gibson, J. Duane; Clark, Dusty; Porter, Dallan

2014-07-01

Details of the software framework for the upcoming in-situ re-aluminization of the 6.5m MMT Observatory (MMTO) primary mirror are presented. This framework includes: 1) a centralized key-value store and data structure server for data exchange between software modules, 2) a newly developed hardware-software interface for faster data sampling and better hardware control, 3) automated control algorithms that are based upon empirical testing, modeling, and simulation of the aluminization process, 4) re-engineered graphical user interfaces (GUI's) that use state-of-the-art web technologies, and 5) redundant relational databases for data logging. Redesign of the software framework has several objectives: 1) automated process control to provide more consistent and uniform mirror coatings, 2) optional manual control of the aluminization process, 3) modular design to allow flexibility in process control and software implementation, 4) faster data sampling and logging rates to better characterize the approximately 100-second aluminization event, and 5) synchronized "real-time" web application GUI's to provide all users with exactly the same data. The framework has been implemented as four modules interconnected by a data store/server. The four modules are integrated into two Linux system services that start automatically at boot-time and remain running at all times. Performance of the software framework is assessed through extensive testing within 2.0 meter and smaller coating chambers at the Sunnyside Test Facility. The redesigned software framework helps ensure that a better performing and longer lasting coating will be achieved during the re-aluminization of the MMTO primary mirror.

Software requirements flow-down and preliminary software design for the G-CLEF spectrograph

NASA Astrophysics Data System (ADS)

Evans, Ian N.; Budynkiewicz, Jamie A.; DePonte Evans, Janet; Miller, Joseph B.; Onyuksel, Cem; Paxson, Charles; Plummer, David A.

2016-08-01

The Giant Magellan Telescope (GMT)-Consortium Large Earth Finder (G-CLEF) is a fiber-fed, precision radial velocity (PRV) optical echelle spectrograph that will be the first light instrument on the GMT. The G-CLEF instrument device control subsystem (IDCS) provides software control of the instrument hardware, including the active feedback loops that are required to meet the G-CLEF PRV stability requirements. The IDCS is also tasked with providing operational support packages that include data reduction pipelines and proposal preparation tools. A formal, but ultimately pragmatic approach is being used to establish a complete and correct set of requirements for both the G-CLEF device control and operational support packages. The device control packages must integrate tightly with the state-machine driven software and controls reference architecture designed by the GMT Organization. A model-based systems engineering methodology is being used to develop a preliminary design that meets these requirements. Through this process we have identified some lessons that have general applicability to the development of software for ground-based instrumentation. For example, tasking an individual with overall responsibility for science/software/hardware integration is a key step to ensuring effective integration between these elements. An operational concept document that includes detailed routine and non- routine operational sequences should be prepared in parallel with the hardware design process to tie together these elements and identify any gaps. Appropriate time-phasing of the hardware and software design phases is important, but revisions to driving requirements that impact software requirements and preliminary design are inevitable. Such revisions must be carefully managed to ensure efficient use of resources.

Software Development for the Hobby-Eberly Telescope's Segment Alignment Maintenance System using LABView

NASA Technical Reports Server (NTRS)

Hall, Drew P.; Ly, William; Howard, Richard T.; Weir, John; Rakoczy, John; Roe, Fred (Technical Monitor)

2002-01-01

The software development for an upgrade to the Hobby-Eberly Telescope (HET) was done in LABView. In order to improve the performance of the HET at the McDonald Observatory, a closed-loop system had to be implemented to keep the mirror segments aligned during periods of observation. The control system, called the Segment Alignment Maintenance System (SAMs), utilized inductive sensors to measure the relative motions of the mirror segments. Software was developed in LABView to tie the sensors, operator interface, and mirror-control motors together. Developing the software in LABView allowed the system to be flexible, understandable, and able to be modified by the end users. Since LABView is built using block diagrams, the software naturally followed the designed control system's block and flow diagrams, and individual software blocks could be easily verified. LABView's many built-in display routines allowed easy visualization of diagnostic and health-monitoring data during testing. Also, since LABView is a multi-platform software package, different programmers could develop the code remotely on various types of machines. LABView s ease of use facilitated rapid prototyping and field testing. There were some unanticipated difficulties in the software development, but the use of LABView as the software "language" for the development of SAMs contributed to the overall success of the project.

Simulation test beds for the space station electrical power system

NASA Technical Reports Server (NTRS)

Sadler, Gerald G.

1988-01-01

NASA Lewis Research Center and its prime contractor are responsible for developing the electrical power system on the space station. The power system will be controlled by a network of distributed processors. Control software will be verified, validated, and tested in hardware and software test beds. Current plans for the software test bed involve using real time and nonreal time simulations of the power system. This paper will discuss the general simulation objectives and configurations, control architecture, interfaces between simulator and controls, types of tests, and facility configurations.

Third-Party Software's Trust Quagmire.

PubMed

Voas, J; Hurlburt, G

2015-12-01

Current software development has trended toward the idea of integrating independent software sub-functions to create more complete software systems. Software sub-functions are often not homegrown - instead they are developed by unknown 3 rd party organizations and reside in software marketplaces owned or controlled by others. Such software sub-functions carry plausible concern in terms of quality, origins, functionality, security, interoperability, to name a few. This article surveys key technical difficulties in confidently building systems from acquired software sub-functions by calling out the principle software supply chain actors.

Collaboration Between NASA Centers of Excellence on Autonomous System Software Development

NASA Technical Reports Server (NTRS)

Goodrich, Charles H.; Larson, William E.; Delgado, H. (Technical Monitor)

2001-01-01

Software for space systems flight operations has its roots in the early days of the space program when computer systems were incapable of supporting highly complex and flexible control logic. Control systems relied on fast data acquisition and supervisory control from a roomful of systems engineers on the ground. Even though computer hardware and software has become many orders of magnitude more capable, space systems have largely adhered to this original paradigm In an effort to break this mold, Kennedy Space Center (KSC) has invested in the development of model-based diagnosis and control applications for ten years having broad experience in both ground and spacecraft systems and software. KSC has now partnered with Ames Research Center (ARC), NASA's Center of Excellence in Information Technology, to create a new paradigm for the control of dynamic space systems. ARC has developed model-based diagnosis and intelligent planning software that enables spacecraft to handle most routine problems automatically and allocate resources in a flexible way to realize mission objectives. ARC demonstrated the utility of onboard diagnosis and planning with an experiment aboard Deep Space I in 1999. This paper highlights the software control system collaboration between KSC and ARC. KSC has developed a Mars In-situ Resource Utilization testbed based on the Reverse Water Gas Shift (RWGS) reaction. This plant, built in KSC's Applied Chemistry Laboratory, is capable of producing the large amount of Oxygen that would be needed to support a Human Mars Mission. KSC and ARC are cooperating to develop an autonomous, fault-tolerant control system for RWGS to meet the need for autonomy on deep space missions. The paper will also describe how the new system software paradigm will be applied to Vehicle Health Monitoring, tested on the new X vehicles and integrated into future launch processing systems.

SMC Message Browser Projects

NASA Technical Reports Server (NTRS)

Wichmann, Benjamin C.

2013-01-01

I work directly with the System Monitoring and Control (SMC) software engineers who develop, test and release custom and commercial software in support of the Kennedy Space Center Spaceport Command and Control System. (SCCS). SMC uses Commercial Off-The-Shelf (COTS) Enterprise Management Systems (EMS) software which provides a centralized subsystem for configuring, monitoring, and controlling SCCS hardware and software used in the Control Rooms. There are multiple projects being worked on using the COTS EMS software. I am currently working with the HP Operations Manager for UNIX (OMU) software which allows Master Console Operators (MCO) to access, view and interpret messages regarding the status of the SCCS hardware and software. The OMU message browser gets cluttered with messages which can make it difficult for the MCO to manage. My main project involves determining ways to reduce the number of messages being displayed in the OMU message browser. I plan to accomplish this task in two different ways: (1) by correlating multiple messages into one single message being displayed and (2) to create policies that will determine the significance of each message and whether or not it needs to be displayed to the MCO. The core idea is to lessen the number of messages being sent to the OMU message browser so the MCO can more effectively use it.

Development of the Software for 30 inch Telescope Control System at KHAO

NASA Astrophysics Data System (ADS)

Mun, B.-S.; Kim, S.-J.; Jang, M.; Min, S.-W.; Seol, K.-H.; Moon, K.-S.

2006-12-01

Even though 30inch optical telescope at Kyung Hee Astronomy Observatory has been used to produce a series of scientific achievements since its first light in 1992, numerous difficulties in the operation of the telescope have hindered the precise observations needed for further researches. Since the currently used PC-TCS (Personal Computer based Telescope Control system) software based on ISA-bus type is outdated, it doesn't have a user friendly interface and make it impossible to scale. Also accumulated errors which are generated by discordance from input and output signals into a motion controller required new control system. Thus we have improved the telescope control system by updating software and modifying mechanical parts. We applied a new BLDC (brushless DC) servo motor system to the mechanical parts of the telescope and developed a control software using Visual Basic 6.0. As a result, we could achieve a high accuracy in controlling of the telescope and use the userfriendly GUI (Graphic User Interface).

Laboratory process control using natural language commands from a personal computer

NASA Technical Reports Server (NTRS)

Will, Herbert A.; Mackin, Michael A.

1989-01-01

PC software is described which provides flexible natural language process control capability with an IBM PC or compatible machine. Hardware requirements include the PC, and suitable hardware interfaces to all controlled devices. Software required includes the Microsoft Disk Operating System (MS-DOS) operating system, a PC-based FORTRAN-77 compiler, and user-written device drivers. Instructions for use of the software are given as well as a description of an application of the system.

15 CFR 734.4 - De minimis U.S. content.

Code of Federal Regulations, 2011 CFR

2011-01-01

... section and the requirements of this paragraph. (1) The U.S. origin commodities or software, if controlled... controlled U.S.-origin commodities or “bundled” with U.S.-origin software valued at 10% or less of the total value of the foreign-made commodity; Notes to paragraph (c)(1): (1) U.S.-origin software is not eligible...

An application generator for rapid prototyping of Ada real-time control software

NASA Technical Reports Server (NTRS)

Johnson, Jim; Biglari, Haik; Lehman, Larry

1990-01-01

The need to increase engineering productivity and decrease software life cycle costs in real-time system development establishes a motivation for a method of rapid prototyping. The design by iterative rapid prototyping technique is described. A tool which facilitates such a design methodology for the generation of embedded control software is described.

15 CFR 740.10 - Servicing and replacement of parts and equipment (RPL).

Code of Federal Regulations, 2010 CFR

2010-01-01

... supporting acts of international terrorism) if the commodity to be repaired is an “aircraft” (as defined in... equipment controlled under ECCN 2A983 or related software controlled under ECCN 2D983. (vi) The conditions... defective or unacceptable U.S.-origin commodities and software. (2) Commodities and software sent to a...

The Influence of Software Complexity on the Maintenance Effort: Case Study on Software Developed within Educational Process

ERIC Educational Resources Information Center

Radulescu, Iulian Ionut

2006-01-01

Software complexity is the most important software quality attribute and a very useful instrument in the study of software quality. Is one of the factors that affect most of the software quality characteristics, including maintainability. It is very important to quantity this influence and identify the means to keep it under control; by using…

Tissue factor expressed by circulating cancer cell-derived microparticles drastically increases the incidence of deep vein thrombosis in mice

PubMed Central

Thomas, G. M.; Brill, A.; Mezouar, S.; Crescence, L.; Gallant, M.; Dubois, C.; Wagner, D. D.

2015-01-01

Background The risk of thrombotic complications such as deep vein thrombosis (DVT) during tumor development is well known. Tumors release into circulation procoagulant microparticles (MPs) that can participate in thrombus formation following vessel injury. The importance of this MP tissue factor (TF) in the initiation of cancer-associated DVT remains uncertain. Objective To address how pancreatic cancer MPs promote DVT in vivo. Methods We combined a DVT mouse model where thrombosis is induced by flow restriction of the inferior vena cava with one of subcutaneous pancreatic cancer in C57BL/6J mice. We infused high and low TF tumor MPs to determine the importance of TF in experimental cancer-associated DVT. Results Both tumor-bearing mice and mice infused with tumor MPs submitted to 3 hours of partial flow restriction developed an occlusive thrombus; fewer than a third of the control mice did. We observed that MPs adhered to neutrophil extracellular traps (NETs), functionally important players during DVT, whereas neither P-selectin nor GPIb were required for the MP recruitment in DVT. The thrombotic phenotype induced by MP infusion was suppressed by hirudin suggesting the importance of thrombin generation. TF carried by tumor MPs was essential to promote DVT as mice infused with low TF tumor MPs had less thrombosis than mice infused with high TF tumor MPs. Conclusions TF expressed on tumor MPs contributes to the increased incidence of cancer-associated venous thrombosis in mice in vivo. These MPs may adhere to NETs formed at the site of thrombosis. PMID:25955268

Off-the-shelf Control of Data Analysis Software

NASA Astrophysics Data System (ADS)

Wampler, S.

The Gemini Project must provide convenient access to data analysis facilities to a wide user community. The international nature of this community makes the selection of data analysis software particularly interesting, with staunch advocates of systems such as ADAM and IRAF among the users. Additionally, the continuing trends towards increased use of networked systems and distributed processing impose additional complexity. To meet these needs, the Gemini Project is proposing the novel approach of using low-cost, off-the-shelf software to abstract out both the control and distribution of data analysis from the functionality of the data analysis software. For example, the orthogonal nature of control versus function means that users might select analysis routines from both ADAM and IRAF as appropriate, distributing these routines across a network of machines. It is the belief of the Gemini Project that this approach results in a system that is highly flexible, maintainable, and inexpensive to develop. The Khoros visualization system is presented as an example of control software that is currently available for providing the control and distribution within a data analysis system. The visual programming environment provided with Khoros is also discussed as a means to providing convenient access to this control.

Incorporating Manual and Autonomous Code Generation

NASA Technical Reports Server (NTRS)

McComas, David

1998-01-01

Code can be generated manually or using code-generated software tools, but how do you interpret the two? This article looks at a design methodology that combines object-oriented design with autonomic code generation for attitude control flight software. Recent improvements in space flight computers are allowing software engineers to spend more time engineering the applications software. The application developed was the attitude control flight software for an astronomical satellite called the Microwave Anisotropy Probe (MAP). The MAP flight system is being designed, developed, and integrated at NASA's Goddard Space Flight Center. The MAP controls engineers are using Integrated Systems Inc.'s MATRIXx for their controls analysis. In addition to providing a graphical analysis for an environment, MATRIXx includes an autonomic code generation facility called AutoCode. This article examines the forces that shaped the final design and describes three highlights of the design process: (1) Defining the manual to autonomic code interface; (2) Applying object-oriented design to the manual flight code; (3) Implementing the object-oriented design in C.

MINDS: A microcomputer interactive data system for 8086-based controllers

NASA Technical Reports Server (NTRS)

Soeder, J. F.

1985-01-01

A microcomputer interactive data system (MINDS) software package for the 8086 family of microcomputers is described. To enhance program understandability and ease of code maintenance, the software is written in PL/M-86, Intel Corporation's high-level system implementation language. The MINDS software is intended to run in residence with real-time digital control software to provide displays of steady-state and transient data. In addition, the MINDS package provides classic monitor capabilities along with extended provisions for debugging an executing control system. The software uses the CP/M-86 operating system developed by Digital Research, Inc., to provide program load capabilities along with a uniform file structure for data and table storage. Finally, a library of input and output subroutines to be used with consoles equipped with PL/M-86 and assembly language is described.

Writing executable assertions to test flight software

NASA Technical Reports Server (NTRS)

Mahmood, A.; Andrews, D. M.; Mccluskey, E. J.

1984-01-01

An executable assertion is a logical statement about the variables or a block of code. If there is no error during execution, the assertion statement results in a true value. Executable assertions can be used for dynamic testing of software. They can be employed for validation during the design phase, and exception and error detection during the operation phase. The present investigation is concerned with the problem of writing executable assertions, taking into account the use of assertions for testing flight software. They can be employed for validation during the design phase, and for exception handling and error detection during the operation phase The digital flight control system and the flight control software are discussed. The considered system provides autopilot and flight director modes of operation for automatic and manual control of the aircraft during all phases of flight. Attention is given to techniques for writing and using assertions to test flight software, an experimental setup to test flight software, and language features to support efficient use of assertions.

Framework for Development of Object-Oriented Software

NASA Technical Reports Server (NTRS)

Perez-Poveda, Gus; Ciavarella, Tony; Nieten, Dan

2004-01-01

The Real-Time Control (RTC) Application Framework is a high-level software framework written in C++ that supports the rapid design and implementation of object-oriented application programs. This framework provides built-in functionality that solves common software development problems within distributed client-server, multi-threaded, and embedded programming environments. When using the RTC Framework to develop software for a specific domain, designers and implementers can focus entirely on the details of the domain-specific software rather than on creating custom solutions, utilities, and frameworks for the complexities of the programming environment. The RTC Framework was originally developed as part of a Space Shuttle Launch Processing System (LPS) replacement project called Checkout and Launch Control System (CLCS). As a result of the framework s development, CLCS software development time was reduced by 66 percent. The framework is generic enough for developing applications outside of the launch-processing system domain. Other applicable high-level domains include command and control systems and simulation/ training systems.

WMAP C&DH Software

NASA Technical Reports Server (NTRS)

Cudmore, Alan; Leath, Tim; Ferrer, Art; Miller, Todd; Walters, Mark; Savadkin, Bruce; Wu, Ji-Wei; Slegel, Steve; Stagmer, Emory

2007-01-01

The command-and-data-handling (C&DH) software of the Wilkinson Microwave Anisotropy Probe (WMAP) spacecraft functions as the sole interface between (1) the spacecraft and its instrument subsystem and (2) ground operations equipment. This software includes a command-decoding and -distribution system, a telemetry/data-handling system, and a data-storage-and-playback system. This software performs onboard processing of attitude sensor data and generates commands for attitude-control actuators in a closed-loop fashion. It also processes stored commands and monitors health and safety functions for the spacecraft and its instrument subsystems. The basic functionality of this software is the same of that of the older C&DH software of the Rossi X-Ray Timing Explorer (RXTE) spacecraft, the main difference being the addition of the attitude-control functionality. Previously, the C&DH and attitude-control computations were performed by different processors because a single RXTE processor did not have enough processing power. The WMAP spacecraft includes a more-powerful processor capable of performing both computations.

Firing Room Remote Application Software Development & Swamp Works Laboratory Robot Software Development

NASA Technical Reports Server (NTRS)

Garcia, Janette

2016-01-01

The National Aeronautics and Space Administration (NASA) is creating a way to send humans beyond low Earth orbit, and later to Mars. Kennedy Space Center (KSC) is working to make this possible by developing a Spaceport Command and Control System (SCCS) which will allow the launch of Space Launch System (SLS). This paper's focus is on the work performed by the author in her first and second part of the internship as a remote application software developer. During the first part of her internship, the author worked on the SCCS's software application layer by assisting multiple ground subsystems teams including Launch Accessories (LACC) and Environmental Control System (ECS) on the design, development, integration, and testing of remote control software applications. Then, on the second part of the internship, the author worked on the development of robot software at the Swamp Works Laboratory which is a research and technology development group which focuses on inventing new technology to help future In-Situ Resource Utilization (ISRU) missions.

How to Choose a Media Retrieval System.

ERIC Educational Resources Information Center

Huber, Joe

1995-01-01

Provides guidelines for schools choosing a media retrieval system. Topics include broadband, baseband, coaxial cable, or fiber optic decisions; the control network; selecting scheduling software; presentation software; device control; control from the classroom; and a comparison of systems offered by five companies. (LRW)

Quality Market: Design and Field Study of Prediction Market for Software Quality Control

ERIC Educational Resources Information Center

Krishnamurthy, Janaki

2010-01-01

Given the increasing competition in the software industry and the critical consequences of software errors, it has become important for companies to achieve high levels of software quality. While cost reduction and timeliness of projects continue to be important measures, software companies are placing increasing attention on identifying the user…

Taking the Observatory to the Astronomer

NASA Astrophysics Data System (ADS)

Bisque, T. M.

1997-05-01

Since 1992, Software Bisque's Remote Astronomy Software has been used by the Mt. Wilson Institute to allow interactive control of a 24" telescope and digital camera via modem. Software Bisque now introduces a comparable, relatively low-cost observatory system that allows powerful, yet "user-friendly" telescope and CCD camera control via the Internet. Utilizing software developed for the Windows 95/NT operating systems, the system offers point-and-click access to comprehensive celestial databases, extremely accurate telescope pointing, rapid download of digital CCD images by one or many users and flexible image processing software for data reduction and analysis. Our presentation will describe how the power of the personal computer has been leveraged to provide professional-level tools to the amateur astronomer, and include a description of this system's software and hardware components. The system software includes TheSky Astronomy Software?, CCDSoft CCD Astronomy Software?, TPoint Telescope Pointing Analysis System? software, Orchestrate? and, optionally, the RealSky CDs. The system hardware includes the Paramount GT-1100? Robotic Telescope Mount, as well as third party CCD cameras, focusers and optical tube assemblies.

Software for Improved Extraction of Data From Tape Storage

NASA Technical Reports Server (NTRS)

Cheng, Chiu-Fu

2003-01-01

A computer program has been written to replace the original software of Racal Storeplex Delta tape recorders, which are used at Stennis Space Center. The original software could be activated by a command- line interface only; the present software offers the option of a command-line or graphical user interface. The present software also offers the option of batch-file operation (activation by a file that contains command lines for operations performed consecutively). The present software is also more reliable than was the original software: The original software was plagued by several deficiencies that made it difficult to execute, modify, and test. In addition, when using the original software to extract data that had been recorded within specified intervals of time, the resolution with which one could control starting and stopping times was no finer than about a second (or, in some cases, several seconds). In contrast, the present software is capable of controlling playback times to within 1/100 second of times specified by the user, assuming that the tape-recorder clock is accurate to within 1/100 second.

Software for Improved Extraction of Data From Tape Storage

NASA Technical Reports Server (NTRS)

Cheng, Chiu-Fu

2002-01-01

A computer program has been written to replace the original software of Racal Storeplex Delta tape recorders, which are still used at Stennis Space Center but have been discontinued by the manufacturer. Whereas the original software could be activated by a command-line interface only, the present software offers the option of a command-line or graphical user interface. The present software also offers the option of batch-file operation (activation by a file that contains command lines for operations performed consecutively). The present software is also more reliable than was the original software: The original software was plagued by several deficiencies that made it difficult to execute, modify, and test. In addition, when using the original software to extract data that had been recorded within specified intervals of time, the resolution with which one could control starting and stopping times was no finer than about a second (or, in some cases, several seconds). In contrast, the present software is capable of controlling playback times to within 1/100 second of times specified by the user, assuming that the tape-recorder clock is accurate to within 1/100 second.

Developing Learning Tool of Control System Engineering Using Matrix Laboratory Software Oriented on Industrial Needs

NASA Astrophysics Data System (ADS)

Isnur Haryudo, Subuh; Imam Agung, Achmad; Firmansyah, Rifqi

2018-04-01

The purpose of this research is to develop learning media of control technique using Matrix Laboratory software with industry requirement approach. Learning media serves as a tool for creating a better and effective teaching and learning situation because it can accelerate the learning process in order to enhance the quality of learning. Control Techniques using Matrix Laboratory software can enlarge the interest and attention of students, with real experience and can grow independent attitude. This research design refers to the use of research and development (R & D) methods that have been modified by multi-disciplinary team-based researchers. This research used Computer based learning method consisting of computer and Matrix Laboratory software which was integrated with props. Matrix Laboratory has the ability to visualize the theory and analysis of the Control System which is an integration of computing, visualization and programming which is easy to use. The result of this instructional media development is to use mathematical equations using Matrix Laboratory software on control system application with DC motor plant and PID (Proportional-Integral-Derivative). Considering that manufacturing in the field of Distributed Control systems (DCSs), Programmable Controllers (PLCs), and Microcontrollers (MCUs) use PID systems in production processes are widely used in industry.

Health management and controls for Earth-to-orbit propulsion systems

NASA Astrophysics Data System (ADS)

Bickford, R. L.

1995-03-01

Avionics and health management technologies increase the safety and reliability while decreasing the overall cost for Earth-to-orbit (ETO) propulsion systems. New ETO propulsion systems will depend on highly reliable fault tolerant flight avionics, advanced sensing systems and artificial intelligence aided software to ensure critical control, safety and maintenance requirements are met in a cost effective manner. Propulsion avionics consist of the engine controller, actuators, sensors, software and ground support elements. In addition to control and safety functions, these elements perform system monitoring for health management. Health management is enhanced by advanced sensing systems and algorithms which provide automated fault detection and enable adaptive control and/or maintenance approaches. Aerojet is developing advanced fault tolerant rocket engine controllers which provide very high levels of reliability. Smart sensors and software systems which significantly enhance fault coverage and enable automated operations are also under development. Smart sensing systems, such as flight capable plume spectrometers, have reached maturity in ground-based applications and are suitable for bridging to flight. Software to detect failed sensors has reached similar maturity. This paper will discuss fault detection and isolation for advanced rocket engine controllers as well as examples of advanced sensing systems and software which significantly improve component failure detection for engine system safety and health management.

Reliability, Safety and Error Recovery for Advanced Control Software

NASA Technical Reports Server (NTRS)

Malin, Jane T.

2003-01-01

For long-duration automated operation of regenerative life support systems in space environments, there is a need for advanced integration and control systems that are significantly more reliable and safe, and that support error recovery and minimization of operational failures. This presentation outlines some challenges of hazardous space environments and complex system interactions that can lead to system accidents. It discusses approaches to hazard analysis and error recovery for control software and challenges of supporting effective intervention by safety software and the crew.

Robust Control for the Mercury Laser Altimeter

NASA Technical Reports Server (NTRS)

Rosenberg, Jacob S.

2006-01-01

Mercury Laser Altimeter Science Algorithms is a software system for controlling the laser altimeter aboard the Messenger spacecraft, which is to enter into orbit about Mercury in 2011. The software will control the altimeter by dynamically modifying hardware inputs for gain, threshold, channel-disable flags, range-window start location, and range-window width, by using ranging information provided by the spacecraft and noise counts from instrument hardware. In addition, because of severe bandwidth restrictions, the software also selects returns for downlink.

Initial flight qualification and operational maintenance of X-29A flight software

NASA Technical Reports Server (NTRS)

Earls, Michael R.; Sitz, Joel R.

1989-01-01

A discussion is presented of some significant aspects of the initial flight qualification and operational maintenance of the flight control system softward for the X-29A technology demonstrator. Flight qualification and maintenance of complex, embedded flight control system software poses unique problems. The X-29A technology demonstrator aircraft has a digital flight control system which incorporates functions generally considered too complex for analog systems. Organizational responsibilities, software assurance issues, tools, and facilities are discussed.

Modular Filter and Source-Management Upgrade of RADAC

NASA Technical Reports Server (NTRS)

Lanzi, R. James; Smith, Donna C.

2007-01-01

In an upgrade of the Range Data Acquisition Computer (RADAC) software, a modular software object library was developed to implement required functionality for filtering of flight-vehicle-tracking data and management of tracking-data sources. (The RADAC software is used to process flight-vehicle metric data for realtime display in the Wallops Flight Facility Range Control Center and Mobile Control Center.)

15 CFR 734.4 - De minimis U.S. content.

Code of Federal Regulations, 2014 CFR

2014-01-01

... this paragraph. (1) The U.S. origin commodities or software, if controlled under ECCNs 5A002.a.1, .a.2... controlled U.S.-origin commodities or “bundled” with U.S.-origin software valued at 10% or less of the total value of the foreign-made commodity; Notes to paragraph (c)(1): (1) U.S.-origin software is not eligible...

Controls Over Copyrighted Computer Software

DTIC Science & Technology

1993-02-19

The Army Audit Agency issued five installation reports as a result of one multilocation audit . The audit found that 41 percent of the computers...ARMY AUDIT AGENCY REPORTS ON COMPUTER SOFTWARE MANAGEMENT The U.S. Army Audit Agency conducted three multilocation audits from March 1988 through...December 1990, covering the acquisition, use, control, and accountability of commercial software. One multilocation audit resulted in five

A new software on TUG-T60 autonomous telescope for astronomical transient events

NASA Astrophysics Data System (ADS)

Dindar, Murat; Helhel, Selçuk; Esenoğlu, Hasan; Parmaksızoğlu, Murat

2015-03-01

Robotic telescopes usually run under the control of a scheduler, which provides high-level control by selecting astronomical targets for observation. TÜBİTAK (Scientific and Technological Research Council of Turkey) National Observatory (TUG)-T60 Robotic Telescope is controlled by open-source OCAAS software, formally named Talon. This study introduces new software which was designed for Talon to catch GRB, GAIA and transient alerts. The new GRB software module (daemon process) alertd is running with all other modules of Talon such as telescoped; focus, dome; camerad and telrun. Maximum slew velocity and acceleration limits of the T60 telescope are enough fast for the GRB and transient observations.

Software Framework for Controlling Unsupervised Scientific Instruments.

PubMed

Schmid, Benjamin; Jahr, Wiebke; Weber, Michael; Huisken, Jan

2016-01-01

Science outreach and communication are gaining more and more importance for conveying the meaning of today's research to the general public. Public exhibitions of scientific instruments can provide hands-on experience with technical advances and their applications in the life sciences. The software of such devices, however, is oftentimes not appropriate for this purpose. In this study, we describe a software framework and the necessary computer configuration that is well suited for exposing a complex self-built and software-controlled instrument such as a microscope to laymen under limited supervision, e.g. in museums or schools. We identify several aspects that must be met by such software, and we describe a design that can simultaneously be used to control either (i) a fully functional instrument in a robust and fail-safe manner, (ii) an instrument that has low-cost or only partially working hardware attached for illustration purposes or (iii) a completely virtual instrument without hardware attached. We describe how to assess the educational success of such a device, how to monitor its operation and how to facilitate its maintenance. The introduced concepts are illustrated using our software to control eduSPIM, a fluorescent light sheet microscope that we are currently exhibiting in a technical museum.

Use of Soft Computing Technologies for a Qualitative and Reliable Engine Control System for Propulsion Systems

NASA Technical Reports Server (NTRS)

Trevino, Luis; Brown, Terry; Crumbley, R. T. (Technical Monitor)

2001-01-01

The problem to be addressed in this paper is to explore how the use of Soft Computing Technologies (SCT) could be employed to improve overall vehicle system safety, reliability, and rocket engine performance by development of a qualitative and reliable engine control system (QRECS). Specifically, this will be addressed by enhancing rocket engine control using SCT, innovative data mining tools, and sound software engineering practices used in Marshall's Flight Software Group (FSG). The principle goals for addressing the issue of quality are to improve software management, software development time, software maintenance, processor execution, fault tolerance and mitigation, and nonlinear control in power level transitions. The intent is not to discuss any shortcomings of existing engine control methodologies, but to provide alternative design choices for control, implementation, performance, and sustaining engineering, all relative to addressing the issue of reliability. The approaches outlined in this paper will require knowledge in the fields of rocket engine propulsion (system level), software engineering for embedded flight software systems, and soft computing technologies (i.e., neural networks, fuzzy logic, data mining, and Bayesian belief networks); some of which are briefed in this paper. For this effort, the targeted demonstration rocket engine testbed is the MC-1 engine (formerly FASTRAC) which is simulated with hardware and software in the Marshall Avionics & Software Testbed (MAST) laboratory that currently resides at NASA's Marshall Space Flight Center, building 4476, and is managed by the Avionics Department. A brief plan of action for design, development, implementation, and testing a Phase One effort for QRECS is given, along with expected results. Phase One will focus on development of a Smart Start Engine Module and a Mainstage Engine Module for proper engine start and mainstage engine operations. The overall intent is to demonstrate that by employing soft computing technologies, the quality and reliability of the overall scheme to engine controller development is further improved and vehicle safety is further insured. The final product that this paper proposes is an approach to development of an alternative low cost engine controller that would be capable of performing in unique vision spacecraft vehicles requiring low cost advanced avionics architectures for autonomous operations from engine pre-start to engine shutdown.

GPM Timeline Inhibits For IT Processing

NASA Technical Reports Server (NTRS)

Dion, Shirley K.

2014-01-01

The Safety Inhibit Timeline Tool was created as one approach to capturing and understanding inhibits and controls from IT through launch. Global Precipitation Measurement (GPM) Mission, which launched from Japan in March 2014, was a joint mission under a partnership between the National Aeronautics and Space Administration (NASA) and the Japan Aerospace Exploration Agency (JAXA). GPM was one of the first NASA Goddard in-house programs that extensively used software controls. Using this tool during the GPM buildup allowed a thorough review of inhibit and safety critical software design for hazardous subsystems such as the high gain antenna boom, solar array, and instrument deployments, transmitter turn-on, propulsion system release, and instrument radar turn-on. The GPM safety team developed a methodology to document software safety as part of the standard hazard report. As a result of this process, a new tool safety inhibit timeline was created for management of inhibits and their controls during spacecraft buildup and testing during IT at GSFC and at the launch range in Japan. The Safety Inhibit Timeline Tool was a pathfinder approach for reviewing software that controls the electrical inhibits. The Safety Inhibit Timeline Tool strengthens the Safety Analysts understanding of the removal of inhibits during the IT process with safety critical software. With this tool, the Safety Analyst can confirm proper safe configuration of a spacecraft during each IT test, track inhibit and software configuration changes, and assess software criticality. In addition to understanding inhibits and controls during IT, the tool allows the Safety Analyst to better communicate to engineers and management the changes in inhibit states with each phase of hardware and software testing and the impact of safety risks. Lessons learned from participating in the GPM campaign at NASA and JAXA will be discussed during this session.

Open Source and Design Thinking at NASA: A Vision for Future Software

NASA Technical Reports Server (NTRS)

Trimble, Jay

2017-01-01

NASA Mission Control Software for the Visualization of data has historically been closed, accessible only to small groups of flight controllers, often bound to a specific mission discipline such as flight dynamics, health and status or mission planning. Open Mission Control Technologies (MCT) provides new capability for NASA mission controllers and, by being fully open source, opens up NASA software for the visualization of mission data to broader communities inside and outside of NASA. Open MCT is the product of a design thinking process within NASA, using participatory design and design sprints to build a product that serves users.

NASA's Software Safety Standard

NASA Technical Reports Server (NTRS)

Ramsay, Christopher M.

2007-01-01

NASA relies more and more on software to control, monitor, and verify its safety critical systems, facilities and operations. Since the 1960's there has hardly been a spacecraft launched that does not have a computer on board that will provide command and control services. There have been recent incidents where software has played a role in high-profile mission failures and hazardous incidents. For example, the Mars Orbiter, Mars Polar Lander, the DART (Demonstration of Autonomous Rendezvous Technology), and MER (Mars Exploration Rover) Spirit anomalies were all caused or contributed to by software. The Mission Control Centers for the Shuttle, ISS, and unmanned programs are highly dependant on software for data displays, analysis, and mission planning. Despite this growing dependence on software control and monitoring, there has been little to no consistent application of software safety practices and methodology to NASA's projects with safety critical software. Meanwhile, academia and private industry have been stepping forward with procedures and standards for safety critical systems and software, for example Dr. Nancy Leveson's book Safeware: System Safety and Computers. The NASA Software Safety Standard, originally published in 1997, was widely ignored due to its complexity and poor organization. It also focused on concepts rather than definite procedural requirements organized around a software project lifecycle. Led by NASA Headquarters Office of Safety and Mission Assurance, the NASA Software Safety Standard has recently undergone a significant update. This new standard provides the procedures and guidelines for evaluating a project for safety criticality and then lays out the minimum project lifecycle requirements to assure the software is created, operated, and maintained in the safest possible manner. This update of the standard clearly delineates the minimum set of software safety requirements for a project without detailing the implementation for those requirements. This allows the projects leeway to meet these requirements in many forms that best suit a particular project's needs and safety risk. In other words, it tells the project what to do, not how to do it. This update also incorporated advances in the state of the practice of software safety from academia and private industry. It addresses some of the more common issues now facing software developers in the NASA environment such as the use of Commercial-Off-the-Shelf Software (COTS), Modified OTS (MOTS), Government OTS (GOTS), and reused software. A team from across NASA developed the update and it has had both NASA-wide internal reviews by software engineering, quality, safety, and project management. It has also had expert external review. This presentation and paper will discuss the new NASA Software Safety Standard, its organization, and key features. It will start with a brief discussion of some NASA mission failures and incidents that had software as one of their root causes. It will then give a brief overview of the NASA Software Safety Process. This will include an overview of the key personnel responsibilities and functions that must be performed for safety-critical software.

A Closed-Loop Proportional-Integral (PI) Control Software for Fully Mechanically Controlled Automated Electron Microscopic Tomography

DOE Office of Scientific and Technical Information (OSTI.GOV)

REN, GANG; LIU, JINXIN; LI, HONGCHANG

A closed-loop proportional-integral (PI) control software is provided for fully mechanically controlled automated electron microscopic tomography. The software is developed based on Gatan DigitalMicrograph, and is compatible with Zeiss LIBRA 120 transmission electron microscope. However, it can be expanded to other TEM instrument with modification. The software consists of a graphical user interface, a digital PI controller, an image analyzing unit, and other drive units (i.e.: image acquire unit and goniometer drive unit). During a tomography data collection process, the image analyzing unit analyzes both the accumulated shift and defocus value of the latest acquired image, and provides the resultsmore » to the digital PI controller. The digital PI control compares the results with the preset values and determines the optimum adjustments of the goniometer. The goniometer drive unit adjusts the spatial position of the specimen according to the instructions given by the digital PI controller for the next tilt angle and image acquisition. The goniometer drive unit achieves high precision positioning by using a backlash elimination method. The major benefits of the software are: 1) the goniometer drive unit keeps pre-aligned/optimized beam conditions unchanged and achieves position tracking solely through mechanical control; 2) the image analyzing unit relies on only historical data and therefore does not require additional images/exposures; 3) the PI controller enables the system to dynamically track the imaging target with extremely low system error.« less

Software feedback for monochromator tuning at UNICAT (abstract)

NASA Astrophysics Data System (ADS)

Jemian, Pete R.

2002-03-01

Automatic tuning of double-crystal monochromators presents an interesting challenge in software. The goal is to either maximize, or hold constant, the throughput of the monochromator. An additional goal of the software feedback is to disable itself when there is no beam and then, at the user's discretion, re-enable itself when the beam returns. These and other routine goals, such as adherence to limits of travel for positioners, are maintained by software controls. Many solutions exist to lock in and maintain a fixed throughput. Among these include a hardware solution involving a wave form generator, and a lock-in amplifier to autocorrelate the movement of a piezoelectric transducer (PZT) providing fine adjustment of the second crystal Bragg angle. This solution does not work when the positioner is a slow acting device such as a stepping motor. Proportional integral differential (PID) loops have been used to provide feedback through software but additional controls must be provided to maximize the monochromator throughput. Presented here is a software variation of the PID loop which meets the above goals. By using two floating point variables as inputs, representing the intensity of x rays measured before and after the monochromator, it attempts to maximize (or hold constant) the ratio of these two inputs by adjusting an output floating point variable. These floating point variables are connected to hardware channels corresponding to detectors and positioners. When the inputs go out of range, the software will stop making adjustments to the control output. Not limited to monochromator feedback, the software could be used, with beam steering positioners, to maintain a measure of beam position. Advantages of this software feedback are the flexibility of its various components. It has been used with stepping motors and PZTs as positioners. Various devices such as ion chambers, scintillation counters, photodiodes, and photoelectron collectors have been used as detectors. The software provides significant cost savings over hardware feedback methods. Presently implemented in EPICS, the software is sufficiently general to any automated instrument control system.

Effective Software Engineering Leadership for Development Programs

ERIC Educational Resources Information Center

Cagle West, Marsha

2010-01-01

Software is a critical component of systems ranging from simple consumer appliances to complex health, nuclear, and flight control systems. The development of quality, reliable, and effective software solutions requires the incorporation of effective software engineering processes and leadership. Processes, approaches, and methodologies for…

Instrumentation: Software-Driven Instrumentation: The New Wave.

ERIC Educational Resources Information Center

Salit, M. L.; Parsons, M. L.

1985-01-01

Software-driven instrumentation makes measurements that demand a computer as an integral part of either control, data acquisition, or data reduction. The structure of such instrumentation, hardware requirements, and software requirements are discussed. Examples of software-driven instrumentation (such as wavelength-modulated continuum source…

JRTF: A Flexible Software Framework for Real-Time Control in Magnetic Confinement Nuclear Fusion Experiments

NASA Astrophysics Data System (ADS)

Zhang, M.; Zheng, G. Z.; Zheng, W.; Chen, Z.; Yuan, T.; Yang, C.

2016-04-01

The magnetic confinement nuclear fusion experiments require various real-time control applications like plasma control. ITER has designed the Fast Plant System Controller (FPSC) for this job. ITER provided hardware and software standards and guidelines for building a FPSC. In order to develop various real-time FPSC applications efficiently, a flexible real-time software framework called J-TEXT real-time framework (JRTF) is developed by J-TEXT tokamak team. JRTF allowed developers to implement different functions as independent and reusable modules called Application Blocks (AB). The AB developers only need to focus on implementing the control tasks or the algorithms. The timing, scheduling, data sharing and eventing are handled by the JRTF pipelines. JRTF provides great flexibility on developing ABs. Unit test against ABs can be developed easily and ABs can even be used in non-JRTF applications. JRTF also provides interfaces allowing JRTF applications to be configured and monitored at runtime. JRTF is compatible with ITER standard FPSC hardware and ITER (Control, Data Access and Communication) CODAC Core software. It can be configured and monitored using (Experimental Physics and Industrial Control System) EPICS. Moreover the JRTF can be ported to different platforms and be integrated with supervisory control software other than EPICS. The paper presents the design and implementation of JRTF as well as brief test results.

Asthma in Adults Fact Sheet

MedlinePlus

... American Lung Association Epidemiology and Statistics Unit using SPSS software. Center for Disease Control and Prevention. Behavioral ... American Lung Association Epidemiology and Statistics Unit using SPSS software. Centers for Disease Control and Prevention. National ...

Design of Genetic Algorithms for Topology Control of Unmanned Vehicles

DTIC Science & Technology

2010-01-01

decentralised topology control mechanism distributed among active running software agents to achieve a uniform spread of terrestrial unmanned vehicles...14. ABSTRACT We present genetic algorithms (GAs) as a decentralised topology control mechanism distributed among active running software agents to...inspired topology control algorithm. The topology control of UVs using a decentralised solution over an unknown geographical terrain is a challenging

The software architecture to control the Cherenkov Telescope Array

NASA Astrophysics Data System (ADS)

Oya, I.; Füßling, M.; Antonino, P. O.; Conforti, V.; Hagge, L.; Melkumyan, D.; Morgenstern, A.; Tosti, G.; Schwanke, U.; Schwarz, J.; Wegner, P.; Colomé, J.; Lyard, E.

2016-07-01

The Cherenkov Telescope Array (CTA) project is an initiative to build two large arrays of Cherenkov gamma- ray telescopes. CTA will be deployed as two installations, one in the northern and the other in the southern hemisphere, containing dozens of telescopes of different sizes. CTA is a big step forward in the field of ground- based gamma-ray astronomy, not only because of the expected scientific return, but also due to the order-of- magnitude larger scale of the instrument to be controlled. The performance requirements associated with such a large and distributed astronomical installation require a thoughtful analysis to determine the best software solutions. The array control and data acquisition (ACTL) work-package within the CTA initiative will deliver the software to control and acquire the data from the CTA instrumentation. In this contribution we present the current status of the formal ACTL system decomposition into software building blocks and the relationships among them. The system is modelled via the Systems Modelling Language (SysML) formalism. To cope with the complexity of the system, this architecture model is sub-divided into different perspectives. The relationships with the stakeholders and external systems are used to create the first perspective, the context of the ACTL software system. Use cases are employed to describe the interaction of those external elements with the ACTL system and are traced to a hierarchy of functionalities (abstract system functions) describing the internal structure of the ACTL system. These functions are then traced to fully specified logical elements (software components), the deployment of which as technical elements, is also described. This modelling approach allows us to decompose the ACTL software in elements to be created and the ow of information within the system, providing us with a clear way to identify sub-system interdependencies. This architectural approach allows us to build the ACTL system model and trace requirements to deliverables (source code, documentation, etc.), and permits the implementation of a flexible use-case driven software development approach thanks to the traceability from use cases to the logical software elements. The Alma Common Software (ACS) container/component framework, used for the control of the Atacama Large Millimeter/submillimeter Array (ALMA) is the basis for the ACTL software and as such it is considered as an integral part of the software architecture.

The Validation by Measurement Theory of Proposed Object-Oriented Software Metrics

NASA Technical Reports Server (NTRS)

Neal, Ralph D.

1996-01-01

Moving software development into the engineering arena requires controllability, and to control a process, it must be measurable. Measuring the process does no good if the product is not also measured, i.e., being the best at producing an inferior product does not define a quality process. Also, not every number extracted from software development is a valid measurement. A valid measurement only results when we are able to verify that the number is representative of the attribute that we wish to measure. Many proposed software metrics are used by practitioners without these metrics ever having been validated, leading to costly but often useless calculations. Several researchers have bemoaned the lack of scientific precision in much of the published software measurement work and have called for validation of software metrics by measurement theory. This dissertation applies measurement theory to validate fifty proposed object-oriented software metrics.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Laros, James H.; Grant, Ryan; Levenhagen, Michael J.

Measuring and controlling the power and energy consumption of high performance computing systems by various components in the software stack is an active research area. Implementations in lower level software layers are beginning to emerge in some production systems, which is very welcome. To be most effective, a portable interface to measurement and control features would significantly facilitate participation by all levels of the software stack. We present a proposal for a standard power Application Programming Interface (API) that endeavors to cover the entire software space, from generic hardware interfaces to the input from the computer facility manager.

The M68HC11 gripper controller software. Thesis

NASA Technical Reports Server (NTRS)

Tsai, Jodi Wei-Duk

1991-01-01

This thesis discusses the development of firmware for the 68HC11 gripper controller. A general description of the software and hardware interfaces is given. The C library interface for the gripper is then described and followed by a detailed discussion of the software architecture of the firmware. A procedure to assemble and download 68HC11 programs is presented in the form of a tutorial. The tools used to implement this environment are then described. Finally, the implementation of the configuration management scheme used to manage all CIRSSE software is presented.

Ground control station software design for micro aerial vehicles

NASA Astrophysics Data System (ADS)

Walendziuk, Wojciech; Oldziej, Daniel; Binczyk, Dawid Przemyslaw; Slowik, Maciej

2017-08-01

This article describes the process of designing the equipment part and the software of a ground control station used for configuring and operating micro unmanned aerial vehicles (UAV). All the works were conducted on a quadrocopter model being a commonly accessible commercial construction. This article contains a characteristics of the research object, the basics of operating the micro aerial vehicles (MAV) and presents components of the ground control station model. It also describes the communication standards for the purpose of building a model of the station. Further part of the work concerns the software of the product - the GIMSO application (Generally Interactive Station for Mobile Objects), which enables the user to manage the actions and communication and control processes from the UAV. The process of creating the software and the field tests of a station model are also presented in the article.

Towards a controlled vocabulary on software engineering education

NASA Astrophysics Data System (ADS)

Pizard, Sebastián; Vallespir, Diego

2017-11-01

Software engineering is the discipline that develops all the aspects of the production of software. Although there are guidelines about what topics to include in a software engineering curricula, it is usually unclear which are the best methods to teach them. In any science discipline the construction of a classification schema is a common approach to understand a thematic area. This study examines previous publications in software engineering education to obtain a first controlled vocabulary (a more formal definition of a classification schema) in the field. Publications from 1988 to 2014 were collected and processed using automatic clustering techniques and the outcomes were analysed manually. The result is an initial controlled vocabulary with a taxonomy form with 43 concepts that were identified as the most used in the research publications. We present the classification of the concepts in three facets: 'what to teach', 'how to teach' and 'where to teach' and the evolution of concepts over time.

AZ-101 Mixer Pump Demonstration Data Acquisition System and Gamma Cart Data Acquisition Control System Software Configuration Management Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

WHITE, D.A.

1999-12-29

This Software Configuration Management Plan (SCMP) provides the instructions for change control of the AZ1101 Mixer Pump Demonstration Data Acquisition System (DAS) and the Sludge Mobilization Cart (Gamma Cart) Data Acquisition and Control System (DACS).

15 CFR 742.15 - Encryption items.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Memorandum of November 15, 1996, exports and reexports of encryption software, like exports and reexports of... because of any informational or theoretical value that such software may reflect, contain, or represent... encryption software are distinguished from controls on other software regulated under the EAR. (a) Licensing...

An approach to developing user interfaces for space systems

NASA Astrophysics Data System (ADS)

Shackelford, Keith; McKinney, Karen

1993-08-01

Inherent weakness in the traditional waterfall model of software development has led to the definition of the spiral model. The spiral model software development lifecycle model, however, has not been applied to NASA projects. This paper describes its use in developing real time user interface software for an Environmental Control and Life Support System (ECLSS) Process Control Prototype at NASA's Marshall Space Flight Center.

A Study of the Use of Ontologies for Building Computer-Aided Control Engineering Self-Learning Educational Software

ERIC Educational Resources Information Center

García, Isaías; Benavides, Carmen; Alaiz, Héctor; Alonso, Angel

2013-01-01

This paper describes research on the use of knowledge models (ontologies) for building computer-aided educational software in the field of control engineering. Ontologies are able to represent in the computer a very rich conceptual model of a given domain. This model can be used later for a number of purposes in different software applications. In…

76 FR 29609 - Wassenaar Arrangement 2010 Plenary Agreements Implementation: Commerce Control List, Definitions...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-20

... apply to computers specially designed for ``civil aircraft'' applications to prevent this control from... section. Adding a new paragraph 5D002.d to control ``software'' designed or modified to enable an item to... 6D003.f.3 and f.4 to control ``software'' and ``source code,'' specially designed for ``real time...

Design Genetic Algorithm Optimization Education Software Based Fuzzy Controller for a Tricopter Fly Path Planning

ERIC Educational Resources Information Center

Tran, Huu-Khoa; Chiou, Juing -Shian; Peng, Shou-Tao

2016-01-01

In this paper, the feasibility of a Genetic Algorithm Optimization (GAO) education software based Fuzzy Logic Controller (GAO-FLC) for simulating the flight motion control of Unmanned Aerial Vehicles (UAVs) is designed. The generated flight trajectories integrate the optimized Scaling Factors (SF) fuzzy controller gains by using GAO algorithm. The…

15 CFR 740.10 - Servicing and replacement of parts and equipment (RPL).

Code of Federal Regulations, 2011 CFR

2011-01-01

... supporting acts of international terrorism) if the commodity to be repaired is an “aircraft” (as defined in... equipment controlled under ECCN 2A983 or related software controlled under ECCN 2D983. (vi) No replacement... object detection equipment controlled under ECCN 2A984 or related software controlled under ECCN 2D984...

15 CFR 740.10 - Servicing and replacement of parts and equipment (RPL).

Code of Federal Regulations, 2013 CFR

2013-01-01

... supporting acts of international terrorism) if the commodity to be repaired is an “aircraft” (as defined in... equipment controlled under ECCN 2A983 or related software controlled under ECCN 2D983. (vi) No replacement... object detection equipment controlled under ECCN 2A984 or related software controlled under ECCN 2D984...

15 CFR 740.10 - Servicing and replacement of parts and equipment (RPL).

Code of Federal Regulations, 2012 CFR

2012-01-01

... supporting acts of international terrorism) if the commodity to be repaired is an “aircraft” (as defined in... equipment controlled under ECCN 2A983 or related software controlled under ECCN 2D983. (vi) No replacement... object detection equipment controlled under ECCN 2A984 or related software controlled under ECCN 2D984...

OpenSQUID: A Flexible Open-Source Software Framework for the Control of SQUID Electronics

DOE PAGES

Jaeckel, Felix T.; Lafler, Randy J.; Boyd, S. T. P.

2013-02-06

We report commercially available computer-controlled SQUID electronics are usually delivered with software providing a basic user interface for adjustment of SQUID tuning parameters, such as bias current, flux offset, and feedback loop settings. However, in a research context it would often be useful to be able to modify this code and/or to have full control over all these parameters from researcher-written software. In the case of the STAR Cryoelectronics PCI/PFL family of SQUID control electronics, the supplied software contains modules for automatic tuning and noise characterization, but does not provide an interface for user code. On the other hand, themore » Magnicon SQUIDViewer software package includes a public application programming interface (API), but lacks auto-tuning and noise characterization features. To overcome these and other limitations, we are developing an "open-source" framework for controlling SQUID electronics which should provide maximal interoperability with user software, a unified user interface for electronics from different manufacturers, and a flexible platform for the rapid development of customized SQUID auto-tuning and other advanced features. Finally, we have completed a first implementation for the STAR Cryoelectronics hardware and have made the source code for this ongoing project available to the research community on SourceForge (http://opensquid.sourceforge.net) under the GNU public license.« less

Integrating automated support for a software management cycle into the TAME system

NASA Technical Reports Server (NTRS)

Sunazuka, Toshihiko; Basili, Victor R.

1989-01-01

Software managers are interested in the quantitative management of software quality, cost and progress. An integrated software management methodology, which can be applied throughout the software life cycle for any number purposes, is required. The TAME (Tailoring A Measurement Environment) methodology is based on the improvement paradigm and the goal/question/metric (GQM) paradigm. This methodology helps generate a software engineering process and measurement environment based on the project characteristics. The SQMAR (software quality measurement and assurance technology) is a software quality metric system and methodology applied to the development processes. It is based on the feed forward control principle. Quality target setting is carried out before the plan-do-check-action activities are performed. These methodologies are integrated to realize goal oriented measurement, process control and visual management. A metric setting procedure based on the GQM paradigm, a management system called the software management cycle (SMC), and its application to a case study based on NASA/SEL data are discussed. The expected effects of SMC are quality improvement, managerial cost reduction, accumulation and reuse of experience, and a highly visual management reporting system.

Multi-axis control based on movement control cards in NC systems

NASA Astrophysics Data System (ADS)

Jiang, Tingbiao; Wei, Yunquan

2005-12-01

Today most movement control cards need special control software of topper computers and are only suitable for fixed-axis controls. Consequently, the number of axes which can be controlled is limited. Advanced manufacture technology develops at a very high speed, and that development brings forth. New requirements for movement control in mechanisms and electronics. This paper introduces products of the 5th generation of movement control cards, PMAC 2A-PC/104, made by the Delta Tau Company in the USA. Based on an analysis of PMAC 2A-PC/104, this paper first describes two aspects relevant to the hardware structure of movement control cards and the interrelated software of the topper computers. Then, two methods are presented for solving these problems. The first method is to set limit switches on the movement control cards; all of them can be used to control each moving axis. The second method is to program applied software with existing programming language (for example, VC ++, Visual Basic, Delphi, and so forth). This program is much easier to operate and expand by its users. By using a limit switch, users can choose different axes in movement control cards. Also, users can change parts of the parameters in the control software of topper computers to realize different control axes. Combining these 2 methods proves to be convenient for realizing multi-axis control in numerical control systems.

Space shuttle on-orbit flight control software requirements, preliminary version

NASA Technical Reports Server (NTRS)

1975-01-01

Software modules associated with various flight control functions for the space shuttle orbiter are described. Data flow, interface requirements, initialization requirements and module sequencing requirements are considered. Block diagrams and tables are included.

Indoor Unmanned Airship System Airborne Control Module Design

NASA Astrophysics Data System (ADS)

YongXia, Gao; YiBo, Li

By adopting STC12C5A60S2 SCM as a system control unit, assisted by appropriate software and hardware resources, we complete the airborne control module's design of unmanned airship system. This paper introduces hardware control module's structure, airship-driven composition and software realization. Verified by the China Science and Technology Museum special-shaped airship,this control module can work well.

[Microcomputer control of a LED stimulus display device].

PubMed

Ohmoto, S; Kikuchi, T; Kumada, T

1987-02-01

A visual stimulus display system controlled by a microcomputer was constructed at low cost. The system consists of a LED stimulus display device, a microcomputer, two interface boards, a pointing device (a "mouse") and two kinds of software. The first software package is written in BASIC. Its functions are: to construct stimulus patterns using the mouse, to construct letter patterns (alphabet, digit, symbols and Japanese letters--kanji, hiragana, katakana), to modify the patterns, to store the patterns on a floppy disc, to translate the patterns into integer data which are used to display the patterns in the second software. The second software package, written in BASIC and machine language, controls display of a sequence of stimulus patterns in predetermined time schedules in visual experiments.

HelioScan: a software framework for controlling in vivo microscopy setups with high hardware flexibility, functional diversity and extendibility.

PubMed

Langer, Dominik; van 't Hoff, Marcel; Keller, Andreas J; Nagaraja, Chetan; Pfäffli, Oliver A; Göldi, Maurice; Kasper, Hansjörg; Helmchen, Fritjof

2013-04-30

Intravital microscopy such as in vivo imaging of brain dynamics is often performed with custom-built microscope setups controlled by custom-written software to meet specific requirements. Continuous technological advancement in the field has created a need for new control software that is flexible enough to support the biological researcher with innovative imaging techniques and provide the developer with a solid platform for quickly and easily implementing new extensions. Here, we introduce HelioScan, a software package written in LabVIEW, as a platform serving this dual role. HelioScan is designed as a collection of components that can be flexibly assembled into microscope control software tailored to the particular hardware and functionality requirements. Moreover, HelioScan provides a software framework, within which new functionality can be implemented in a quick and structured manner. A specific HelioScan application assembles at run-time from individual software components, based on user-definable configuration files. Due to its component-based architecture, HelioScan can exploit synergies of multiple developers working in parallel on different components in a community effort. We exemplify the capabilities and versatility of HelioScan by demonstrating several in vivo brain imaging modes, including camera-based intrinsic optical signal imaging for functional mapping of cortical areas, standard two-photon laser-scanning microscopy using galvanometric mirrors, and high-speed in vivo two-photon calcium imaging using either acousto-optic deflectors or a resonant scanner. We recommend HelioScan as a convenient software framework for the in vivo imaging community. Copyright © 2013 Elsevier B.V. All rights reserved.

Software development to support sensor control of robot arc welding

NASA Technical Reports Server (NTRS)

Silas, F. R., Jr.

1986-01-01

The development of software for a Digital Equipment Corporation MINC-23 Laboratory Computer to provide functions of a workcell host computer for Space Shuttle Main Engine (SSME) robotic welding is documented. Routines were written to transfer robot programs between the MINC and an Advanced Robotic Cyro 750 welding robot. Other routines provide advanced program editing features while additional software allows communicatin with a remote computer aided design system. Access to special robot functions were provided to allow advanced control of weld seam tracking and process control for future development programs.

Note: Tormenta: An open source Python-powered control software for camera based optical microscopy.

PubMed

Barabas, Federico M; Masullo, Luciano A; Stefani, Fernando D

2016-12-01

Until recently, PC control and synchronization of scientific instruments was only possible through closed-source expensive frameworks like National Instruments' LabVIEW. Nowadays, efficient cost-free alternatives are available in the context of a continuously growing community of open-source software developers. Here, we report on Tormenta, a modular open-source software for the control of camera-based optical microscopes. Tormenta is built on Python, works on multiple operating systems, and includes some key features for fluorescence nanoscopy based on single molecule localization.

Note: Tormenta: An open source Python-powered control software for camera based optical microscopy

NASA Astrophysics Data System (ADS)

Barabas, Federico M.; Masullo, Luciano A.; Stefani, Fernando D.

2016-12-01

Until recently, PC control and synchronization of scientific instruments was only possible through closed-source expensive frameworks like National Instruments' LabVIEW. Nowadays, efficient cost-free alternatives are available in the context of a continuously growing community of open-source software developers. Here, we report on Tormenta, a modular open-source software for the control of camera-based optical microscopes. Tormenta is built on Python, works on multiple operating systems, and includes some key features for fluorescence nanoscopy based on single molecule localization.

NEWFIRM Software--System Integration Using OPC

NASA Astrophysics Data System (ADS)

Daly, P. N.

2004-07-01

The NOAO Extremely Wide-Field Infra-Red Mosaic (NEWFIRM) camera is being built to satisfy the survey science requirements on the KPNO Mayall and CTIO Blanco 4m telescopes in an era of 8m+ aperture telescopes. Rather than re-invent the wheel, the software system to control the instrument has taken existing software packages and re-used what is appropriate. The result is an end-to-end observation control system using technology components from DRAMA, ORAC, observing tools, GWC, existing in-house motor controllers and new developments like the MONSOON pixel server.

Microcomputer technology applications: Charger and regulator software for a breadboard programmable power processor

NASA Technical Reports Server (NTRS)

Green, D. M.

1978-01-01

Software programs are described, one which implements a voltage regulation function, and one which implements a charger function with peak-power tracking of its input. The software, written in modular fashion, is intended as a vehicle for further experimentation with the P-3 system. A control teleprinter allows an operator to make parameter modifications to the control algorithm during experiments. The programs require 3K ROM and 2K ram each. User manuals for each system are included as well as a third program for simple I/O control.

Feature tracking CMR reveals abnormal strain in preclinical arrhythmogenic right ventricular dysplasia/ cardiomyopathy: a multisoftware feasibility and clinical implementation study.

PubMed

Bourfiss, Mimount; Vigneault, Davis M; Aliyari Ghasebeh, Mounes; Murray, Brittney; James, Cynthia A; Tichnell, Crystal; Mohamed Hoesein, Firdaus A; Zimmerman, Stefan L; Kamel, Ihab R; Calkins, Hugh; Tandri, Harikrishna; Velthuis, Birgitta K; Bluemke, David A; Te Riele, Anneline S J M

2017-09-01

Regional right ventricular (RV) dysfunction is the hallmark of Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (ARVD/C), but is currently only qualitatively evaluated in the clinical setting. Feature Tracking Cardiovascular Magnetic Resonance (FT-CMR) is a novel quantitative method that uses cine CMR to calculate strain values. However, most prior FT-CMR studies in ARVD/C have focused on global RV strain using different software methods, complicating implementation of FT-CMR in clinical practice. We aimed to assess the clinical value of global and regional strain using FT-CMR in ARVD/C and to determine differences between commercially available FT-CMR software packages. We analyzed cine CMR images of 110 subjects (39 overt ARVD/C [mutation+/phenotype+], 40 preclinical ARVD/C [mutation+/phenotype-] and 31 control) for global and regional (subtricuspid, anterior, apical) RV strain in the horizontal longitudinal axis using four FT-CMR software methods (Multimodality Tissue Tracking, TomTec, Medis and Circle Cardiovascular Imaging). Intersoftware agreement was assessed using Bland Altman plots. For global strain, all methods showed reduced strain in overt ARVD/C patients compared to control subjects (p < 0.041), whereas none distinguished preclinical from control subjects (p > 0.275). For regional strain, overt ARVD/C patients showed reduced strain compared to control subjects in all segments which reached statistical significance in the subtricuspid region for all software methods (p < 0.037), in the anterior wall for two methods (p < 0.005) and in the apex for one method (p = 0.012). Preclinical subjects showed abnormal subtricuspid strain compared to control subjects using one of the software methods (p = 0.009). Agreement between software methods for absolute strain values was low (Intraclass Correlation Coefficient = 0.373). Despite large intersoftware variability of FT-CMR derived strain values, all four software methods distinguished overt ARVD/C patients from control subjects by both global and subtricuspid strain values. In the subtricuspid region, one software package distinguished preclinical from control subjects, suggesting the potential to identify early ARVD/C prior to overt disease expression.

Can your software engineer program your PLC?

NASA Astrophysics Data System (ADS)

Borrowman, Alastair J.; Taylor, Philip

2016-07-01

The use of Programmable Logic Controllers (PLCs) in the control of large physics experiments is ubiquitous1, 2, 3. The programming of these controllers is normally the domain of engineers with a background in electronics, this paper introduces PLC program development from the software engineer's perspective. PLC programs provide the link between control software running on PC architecture systems and physical hardware controlled and monitored by digital and analog signals. The higher-level software running on the PC is typically responsible for accepting operator input and from this deciding when and how hardware connected to the PLC is controlled. The PLC accepts demands from the PC, considers the current state of its connected hardware and if correct to do so (based upon interlocks or other constraints) adjusts its hardware output signals appropriately for the PC's demands. A published ICD (Interface Control Document) defines the PLC memory locations available to be written and read by the PC to control and monitor the hardware. Historically the method of programming PLCs has been ladder diagrams that closely resemble circuit diagrams, however, PLC manufacturers nowadays also provide, and promote, the use of higher-level programming languages4. Based on techniques used in the development of high-level PC software to control PLCs for multiple telescopes, this paper examines the development of PLC programs to operate the hardware of a medical cyclotron beamline controlled from a PC using the Experimental Physics and Industrial Control System (EPICS), which is also widely used in telescope control5, 6, 7. The PLC used is the new generation Siemens S7-1200 programmed using Siemens Pascal based Structured Control Language (SCL), which is their implementation of Structured Text (ST). The approach described is that from a software engineer's perspective, utilising Siemens Totally Integrated Automation (TIA) Portal integrated development environment (IDE) to create modular PLC programs based upon reusable functions capable of being unit tested without the PLC connected to hardware. Emphasis has been placed on designing an interface between EPICS and SCL that enforces correct operation of hardware through stringent separation of PC accessible PLC memory and hardware I/O addresses used only by the PLC. The paper also introduces the method used to automate the creation, from the same source document, the PLC memory structure (tag) definitions (defining memory used to access hardware I/O and that accessed by the PC) and creation of the PC program data structures (EPICS database records) used to access the permitted PLC addresses. From direct experience this paper demonstrates the advantages of PLC program development being shared between electronic and software engineers, to enable use of the most appropriate processes from both the perspective of the hardware and the higher-level software used to control it.

Verification of operation of the actuator control system using the integration the B&R Automation Studio software with a virtual model of the actuator system

NASA Astrophysics Data System (ADS)

Herbuś, K.; Ociepka, P.

2017-08-01

In the work is analysed a sequential control system of a machine for separating and grouping work pieces for processing. Whereas, the area of the considered problem is related with verification of operation of an actuator system of an electro-pneumatic control system equipped with a PLC controller. Wherein to verification is subjected the way of operation of actuators in view of logic relationships assumed in the control system. The actuators of the considered control system were three drives of linear motion (pneumatic cylinders). And the logical structure of the system of operation of the control system is based on the signals flow graph. The tested logical structure of operation of the electro-pneumatic control system was implemented in the Automation Studio software of B&R company. This software is used to create programs for the PLC controllers. Next, in the FluidSIM software was created the model of the actuator system of the control system of a machine. To verify the created program for the PLC controller, simulating the operation of the created model, it was utilized the approach of integration these two programs using the tool for data exchange in the form of the OPC server.

E-Control: First Public Release of Remote Control Software for VLBI Telescopes

NASA Technical Reports Server (NTRS)

Neidhardt, Alexander; Ettl, Martin; Rottmann, Helge; Ploetz, Christian; Muehlbauer, Matthias; Hase, Hayo; Alef, Walter; Sobarzo, Sergio; Herrera, Cristian; Himwich, Ed

2010-01-01

Automating and remotely controlling observations are important for future operations in a Global Geodetic Observing System (GGOS). At the Geodetic Observatory Wettzell, in cooperation with the Max-Planck-Institute for Radio Astronomy in Bonn, a software extension to the existing NASA Field System has been developed for remote control. It uses the principle of a remotely accessible, autonomous process cell as a server extension for the Field System. The communication is realized for low transfer rates using Remote Procedure Calls (RPC). It uses generative programming with the interface software generator idl2rpc.pl developed at Wettzell. The user interacts with this system over a modern graphical user interface created with wxWidgets. For security reasons the communication is automatically tunneled through a Secure Shell (SSH) session to the telescope. There are already successful test observations with the telescopes at O Higgins, Concepcion, and Wettzell. At Wettzell the software is already used routinely for weekend observations. Therefore the first public release of the software is now available, which will also be useful for other telescopes.

Developing of an automation for therapy dosimetry systems by using labview software

NASA Astrophysics Data System (ADS)

Aydin, Selim; Kam, Erol

2018-06-01

Traceability, accuracy and consistency of radiation measurements are essential in radiation dosimetry, particularly in radiotherapy, where the outcome of treatments is highly dependent on the radiation dose delivered to patients. Therefore it is very important to provide reliable, accurate and fast calibration services for therapy dosimeters since the radiation dose delivered to a radiotherapy patient is directly related to accuracy and reliability of these devices. In this study, we report the performance of in-house developed computer controlled data acquisition and monitoring software for the commercially available radiation therapy electrometers. LabVIEW® software suite is used to provide reliable, fast and accurate calibration services. The software also collects environmental data such as temperature, pressure and humidity in order to use to use these them in correction factor calculations. By using this software tool, a better control over the calibration process is achieved and the need for human intervention is reduced. This is the first software that can control frequently used dosimeter systems, in radiation thereapy field at hospitals, such as Unidos Webline, Unidos E, Dose-1 and PC Electrometers.

Getting expert systems off the ground: Lessons learned from integrating model-based diagnostics with prototype flight hardware

NASA Technical Reports Server (NTRS)

Stephan, Amy; Erikson, Carol A.

1991-01-01

As an initial attempt to introduce expert system technology into an onboard environment, a model based diagnostic system using the TRW MARPLE software tool was integrated with prototype flight hardware and its corresponding control software. Because this experiment was designed primarily to test the effectiveness of the model based reasoning technique used, the expert system ran on a separate hardware platform, and interactions between the control software and the model based diagnostics were limited. While this project met its objective of showing that model based reasoning can effectively isolate failures in flight hardware, it also identified the need for an integrated development path for expert system and control software for onboard applications. In developing expert systems that are ready for flight, artificial intelligence techniques must be evaluated to determine whether they offer a real advantage onboard, identify which diagnostic functions should be performed by the expert systems and which are better left to the procedural software, and work closely with both the hardware and the software developers from the beginning of a project to produce a well designed and thoroughly integrated application.

Development of MATLAB software to control data acquisition from a multichannel systems multi-electrode array.

PubMed

Messier, Erik

2016-08-01

A Multichannel Systems (MCS) microelectrode array data acquisition (DAQ) unit is used to collect multichannel electrograms (EGM) from a Langendorff perfused rabbit heart system to study sudden cardiac death (SCD). MCS provides software through which data being processed by the DAQ unit can be displayed and saved, but this software's combined utility with MATLAB is not very effective. MCSs software stores recorded EGM data in a MathCad (MCD) format, which is then converted to a text file format. These text files are very large, and it is therefore very time consuming to import the EGM data into MATLAB for real-time analysis. Therefore, customized MATLAB software was developed to control the acquisition of data from the MCS DAQ unit, and provide specific laboratory accommodations for this study of SCD. The developed DAQ unit control software will be able to accurately: provide real time display of EGM signals; record and save EGM signals in MATLAB in a desired format; and produce real time analysis of the EGM signals; all through an intuitive GUI.

Space-Shuttle Emulator Software

NASA Technical Reports Server (NTRS)

Arnold, Scott; Askew, Bill; Barry, Matthew R.; Leigh, Agnes; Mermelstein, Scott; Owens, James; Payne, Dan; Pemble, Jim; Sollinger, John; Thompson, Hiram;

Control Software for Advanced Video Guidance Sensor

NASA Technical Reports Server (NTRS)

Howard, Richard T.; Book, Michael L.; Bryan, Thomas C.

2006-01-01

Embedded software has been developed specifically for controlling an Advanced Video Guidance Sensor (AVGS). A Video Guidance Sensor is an optoelectronic system that provides guidance for automated docking of two vehicles. Such a system includes pulsed laser diodes and a video camera, the output of which is digitized. From the positions of digitized target images and known geometric relationships, the relative position and orientation of the vehicles are computed. The present software consists of two subprograms running in two processors that are parts of the AVGS. The subprogram in the first processor receives commands from an external source, checks the commands for correctness, performs commanded non-image-data-processing control functions, and sends image data processing parts of commands to the second processor. The subprogram in the second processor processes image data as commanded. Upon power-up, the software performs basic tests of functionality, then effects a transition to a standby mode. When a command is received, the software goes into one of several operational modes (e.g. acquisition or tracking). The software then returns, to the external source, the data appropriate to the command.

The nuMOIRCS project: detector upgrade overview and early commissioning results

NASA Astrophysics Data System (ADS)

Walawender, Josh; Wung, Matthew; Fabricius, Maximilian; Tanaka, Ichi; Arimoto, Nobuo; Cook, David; Elms, Brian; Hashiba, Yasuhito; Hu, Yen-Sang; Iwata, Ikuru; Nishimura, Tetsuo; Omata, Koji; Takato, Naruhisa; Wang, Shiang-Yu; Weber, Mark

2016-08-01

In 2014 and 2015 the Multi-Object InfraRed Camera and Spectrograph (MOIRCS) instrument at the Subaru Telescope on Maunakea is underwent a significant modernization and upgrade project. We upgraded the two Hawaii2 detectors to Hawaii2-RG models, modernized the cryogenic temperature control system, and rewrote much of the instrument control software. The detector upgrade replaced the Hawaii2 detectors which use the Tohoku University Focal Plane Array Controller (TUFPAC) electronics with Hawaii2-RG detectors using SIDECAR ASIC (a fully integrated FPA controller system-on-a-chip) and a SAM interface card. We achieved an improvement in read noise by a factor of about 2 with this detector and electronics upgrade. The cryogenic temperature control upgrade focused on modernizing the components and making the procedures for warm up and cool down of the instrument safer. We have moved PID control loops out of the instrument control software and into Lakeshore model 336 cryogenic temperature controllers and have added interlocks on the warming systems to prevent overheating of the instrument. Much of the instrument control software has also been re-written. This was necessitated by the different interface to the detector electronics (ASIC and SAM vs. TUFPAC) and by the desire to modernize the interface to the telescope control software which has been updated to Subaru's "Gen2" system since the time of MOIRCS construction and first light. The new software is also designed to increase reliability of operation of the instrument, decrease overheads, and be easier for night time operators and support astronomers to use.

49 CFR 238.105 - Train electronic hardware and software safety.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Train electronic hardware and software safety. 238... and General Requirements § 238.105 Train electronic hardware and software safety. The requirements of this section apply to electronic hardware and software used to control or monitor safety functions in...

49 CFR 238.105 - Train electronic hardware and software safety.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Train electronic hardware and software safety. 238... and General Requirements § 238.105 Train electronic hardware and software safety. The requirements of this section apply to electronic hardware and software used to control or monitor safety functions in...

15 CFR Supplement No. 3 to Part 774 - Statements of Understanding

Code of Federal Regulations, 2011 CFR

2011-01-01

...” that “incorporate” commodities or software on the Commerce Control List (Supplement No. 1 to part 774... medical research). (2) Commodities or software are considered “incorporated” if the commodity or software... medical equipment; and exported or reexported with the medical equipment. (3) Except for such software...

49 CFR 238.105 - Train electronic hardware and software safety.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Train electronic hardware and software safety. 238... and General Requirements § 238.105 Train electronic hardware and software safety. The requirements of this section apply to electronic hardware and software used to control or monitor safety functions in...

49 CFR 238.105 - Train electronic hardware and software safety.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Train electronic hardware and software safety. 238... and General Requirements § 238.105 Train electronic hardware and software safety. The requirements of this section apply to electronic hardware and software used to control or monitor safety functions in...

On Quality and Measures in Software Engineering

ERIC Educational Resources Information Center

Bucur, Ion I.

2006-01-01

Complexity measures are mainly used to estimate vital information about reliability and maintainability of software systems from regular analysis of the source code. Such measures also provide constant feedback during a software project to assist the control of the development procedure. There exist several models to classify a software product's…

Generation of Controlled Analog Emissions from Embedded Devices using Software Stress Methods

DTIC Science & Technology

2017-03-01

Generation of Controlled Analog Emissions from Embedded Devices using Software Stress Methods Oren Sternberg, Jonathan H. Nelson, Israel Perez...Abstract: In this paper, we present a new method that uses software diagnostic tools to study the generation of induced spurious physical emissions from...types of attacks warrants an understanding of unwanted signal generation. We examine this connection by observing the emission profile of an embedded

Electronic and software subsystems for an autonomous roving vehicle. M.S. Thesis

NASA Technical Reports Server (NTRS)

Doig, G. A.

1980-01-01

The complete electronics packaging which controls the Mars roving vehicle is described in order to provide a broad overview of the systems that are part of that package. Some software debugging tools are also discussed. Particular emphasis is given to those systems that are controlled by the microprocessor. These include the laser mast, the telemetry system, the command link prime interface board, and the prime software.

Army/NASA small turboshaft engine digital controls research program

NASA Technical Reports Server (NTRS)

Sellers, J. F.; Baez, A. N.

1981-01-01

The emphasis of a program to conduct digital controls research for small turboshaft engines is on engine test evaluation of advanced control logic using a flexible microprocessor based digital control system designed specifically for research on advanced control logic. Control software is stored in programmable memory. New control algorithms may be stored in a floppy disk and loaded directly into memory. This feature facilitates comparative evaluation of different advanced control modes. The central processor in the digital control is an Intel 8086 16 bit microprocessor. Control software is programmed in assembly language. Software checkout is accomplished prior to engine test by connecting the digital control to a real time hybrid computer simulation of the engine. The engine currently installed in the facility has a hydromechanical control modified to allow electrohydraulic fuel metering and VG actuation by the digital control. Simulation results are presented which show that the modern control reduces the transient rotor speed droop caused by unanticipated load changes such as cyclic pitch or wind gust transients.

Integrated Control System Engineering Support.

DTIC Science & Technology

1984-12-01

interference susceptibility. " Study multiplex bus loading requirements. Flight Control Software 0 " Demonstrate efficiencies of modular software and...Major technical thrusts include the development of: (a) task-tailored mutimode con- trol laws incorporating direct force and weapon line pointing

A comparison of two software architectural styles for space-based control systems

NASA Technical Reports Server (NTRS)

Dvorak, D.

2003-01-01

In the hardware/software design of control systems it is almost an article of faith to decompose a system into loosely coupled subsystems, with state variables encapsulated inside device and subsystem objects.

AMBER instrument control software

NASA Astrophysics Data System (ADS)

Le Coarer, Etienne P.; Zins, Gerard; Gluck, Laurence; Duvert, Gilles; Driebe, Thomas; Ohnaka, Keiichi; Heininger, Matthias; Connot, Claus; Behrend, Jan; Dugue, Michel; Clausse, Jean Michel; Millour, Florentin

2004-09-01

AMBER (Astronomical Multiple BEam Recombiner) is a 3 aperture interferometric recombiner operating between 1 and 2.5 um, for the Very Large Telescope Interferometer (VLTI). The control software of the instrument, based on the VLT Common Software, has been written to comply with specific features of the AMBER hardware, such as the Infrared detector read out modes or piezo stage drivers, as well as with the very specific operation modes of an interferomtric instrument. In this respect, the AMBER control software was designed to insure that all operations, from the preparation of the observations to the control/command of the instrument during the observations, would be kept as simple as possible for the users and operators, opening the use of an interferometric instrument to the largest community of astronomers. Peculiar attention was given to internal checks and calibration procedures both to evaluate data quality in real time, and improve the successes of long term UV plane coverage observations.

Space station dynamics, attitude control and momentum management

NASA Technical Reports Server (NTRS)

Sunkel, John W.; Singh, Ramen P.; Vengopal, Ravi

1989-01-01

The Space Station Attitude Control System software test-bed provides a rigorous environment for the design, development and functional verification of GN and C algorithms and software. The approach taken for the simulation of the vehicle dynamics and environmental models using a computationally efficient algorithm is discussed. The simulation includes capabilities for docking/berthing dynamics, prescribed motion dynamics associated with the Mobile Remote Manipulator System (MRMS) and microgravity disturbances. The vehicle dynamics module interfaces with the test-bed through the central Communicator facility which is in turn driven by the Station Control Simulator (SCS) Executive. The Communicator addresses issues such as the interface between the discrete flight software and the continuous vehicle dynamics, and multi-programming aspects such as the complex flow of control in real-time programs. Combined with the flight software and redundancy management modules, the facility provides a flexible, user-oriented simulation platform.

Hardware/software codesign for embedded RISC core

NASA Astrophysics Data System (ADS)

Liu, Peng

2001-12-01

This paper describes hardware/software codesign method of the extendible embedded RISC core VIRGO, which based on MIPS-I instruction set architecture. VIRGO is described by Verilog hardware description language that has five-stage pipeline with shared 32-bit cache/memory interface, and it is controlled by distributed control scheme. Every pipeline stage has one small controller, which controls the pipeline stage status and cooperation among the pipeline phase. Since description use high level language and structure is distributed, VIRGO core has highly extension that can meet the requirements of application. We take look at the high-definition television MPEG2 MPHL decoder chip, constructed the hardware/software codesign virtual prototyping machine that can research on VIRGO core instruction set architecture, and system on chip memory size requirements, and system on chip software, etc. We also can evaluate the system on chip design and RISC instruction set based on the virtual prototyping machine platform.

The Diamond Beamline Controls and Data Acquisition Software Architecture

NASA Astrophysics Data System (ADS)

Rees, N.

2010-06-01

The software for the Diamond Light Source beamlines[1] is based on two complementary software frameworks: low level control is provided by the Experimental Physics and Industrial Control System (EPICS) framework[2][3] and the high level user interface is provided by the Java based Generic Data Acquisition or GDA[4][5]. EPICS provides a widely used, robust, generic interface across a wide range of hardware where the user interfaces are focused on serving the needs of engineers and beamline scientists to obtain detailed low level views of all aspects of the beamline control systems. The GDA system provides a high-level system that combines an understanding of scientific concepts, such as reciprocal lattice coordinates, a flexible python syntax scripting interface for the scientific user to control their data acquisition, and graphical user interfaces where necessary. This paper describes the beamline software architecture in more detail, highlighting how these complementary frameworks provide a flexible system that can accommodate a wide range of requirements.

Onboard utilization of ground control points for image correction. Volume 3: Ground control point simulation software design

NASA Technical Reports Server (NTRS)

1981-01-01

The software developed to simulate the ground control point navigation system is described. The Ground Control Point Simulation Program (GCPSIM) is designed as an analysis tool to predict the performance of the navigation system. The system consists of two star trackers, a global positioning system receiver, a gyro package, and a landmark tracker.

Markov Chains For Testing Redundant Software

NASA Technical Reports Server (NTRS)

White, Allan L.; Sjogren, Jon A.

1990-01-01

Preliminary design developed for validation experiment that addresses problems unique to assuring extremely high quality of multiple-version programs in process-control software. Approach takes into account inertia of controlled system in sense it takes more than one failure of control program to cause controlled system to fail. Verification procedure consists of two steps: experimentation (numerical simulation) and computation, with Markov model for each step.

Closing the Certification Gaps in Adaptive Flight Control Software

NASA Technical Reports Server (NTRS)

Jacklin, Stephen A.

2008-01-01

Over the last five decades, extensive research has been performed to design and develop adaptive control systems for aerospace systems and other applications where the capability to change controller behavior at different operating conditions is highly desirable. Although adaptive flight control has been partially implemented through the use of gain-scheduled control, truly adaptive control systems using learning algorithms and on-line system identification methods have not seen commercial deployment. The reason is that the certification process for adaptive flight control software for use in national air space has not yet been decided. The purpose of this paper is to examine the gaps between the state-of-the-art methodologies used to certify conventional (i.e., non-adaptive) flight control system software and what will likely to be needed to satisfy FAA airworthiness requirements. These gaps include the lack of a certification plan or process guide, the need to develop verification and validation tools and methodologies to analyze adaptive controller stability and convergence, as well as the development of metrics to evaluate adaptive controller performance at off-nominal flight conditions. This paper presents the major certification gap areas, a description of the current state of the verification methodologies, and what further research efforts will likely be needed to close the gaps remaining in current certification practices. It is envisioned that closing the gap will require certain advances in simulation methods, comprehensive methods to determine learning algorithm stability and convergence rates, the development of performance metrics for adaptive controllers, the application of formal software assurance methods, the application of on-line software monitoring tools for adaptive controller health assessment, and the development of a certification case for adaptive system safety of flight.

Effective organizational solutions for implementation of DBMS software packages

NASA Technical Reports Server (NTRS)

Jones, D.

1984-01-01

The space telescope management information system development effort is a guideline for discussing effective organizational solutions used in implementing DBMS software. Focus is on the importance of strategic planning. The value of constructing an information system architecture to conform to the organization's managerial needs, the need for a senior decision maker, dealing with shifting user requirements, and the establishment of a reliable working relationship with the DBMS vendor are examined. Requirements for a schedule to demonstrate progress against a defined timeline and the importance of continued monitoring for production software control, production data control, and software enhancements are also discussed.

NASA/NBS (National Aeronautics and Space Administration/National Bureau of Standards) standard reference model for telerobot control system architecture (NASREM)

NASA Technical Reports Server (NTRS)

Albus, James S.; Mccain, Harry G.; Lumia, Ronald

1989-01-01

The document describes the NASA Standard Reference Model (NASREM) Architecture for the Space Station Telerobot Control System. It defines the functional requirements and high level specifications of the control system for the NASA space Station document for the functional specification, and a guideline for the development of the control system architecture, of the 10C Flight Telerobot Servicer. The NASREM telerobot control system architecture defines a set of standard modules and interfaces which facilitates software design, development, validation, and test, and make possible the integration of telerobotics software from a wide variety of sources. Standard interfaces also provide the software hooks necessary to incrementally upgrade future Flight Telerobot Systems as new capabilities develop in computer science, robotics, and autonomous system control.

Guidance and Control Software,

DTIC Science & Technology

1980-05-01

commitments of function, cost, and schedule . The phrase "software engineering" was intended to contrast with the phrase "computer science" the latter aims...the software problems of cost, delivery schedule , and quality were gradually being recognized at the highest management levels. Thus, in a project... schedule dates. Although the analysis of software problems indicated that the entire software development process (figure 1) needed new methods, only

Software Considerations for Subscale Flight Testing of Experimental Control Laws

NASA Technical Reports Server (NTRS)

Murch, Austin M.; Cox, David E.; Cunningham, Kevin

2009-01-01

The NASA AirSTAR system has been designed to address the challenges associated with safe and efficient subscale flight testing of research control laws in adverse flight conditions. In this paper, software elements of this system are described, with an emphasis on components which allow for rapid prototyping and deployment of aircraft control laws. Through model-based design and automatic coding a common code-base is used for desktop analysis, piloted simulation and real-time flight control. The flight control system provides the ability to rapidly integrate and test multiple research control laws and to emulate component or sensor failures. Integrated integrity monitoring systems provide aircraft structural load protection, isolate the system from control algorithm failures, and monitor the health of telemetry streams. Finally, issues associated with software configuration management and code modularity are briefly discussed.

Evaluation of the efficiency and reliability of software generated by code generators

NASA Technical Reports Server (NTRS)

Schreur, Barbara

1994-01-01

There are numerous studies which show that CASE Tools greatly facilitate software development. As a result of these advantages, an increasing amount of software development is done with CASE Tools. As more software engineers become proficient with these tools, their experience and feedback lead to further development with the tools themselves. What has not been widely studied, however, is the reliability and efficiency of the actual code produced by the CASE Tools. This investigation considered these matters. Three segments of code generated by MATRIXx, one of many commercially available CASE Tools, were chosen for analysis: ETOFLIGHT, a portion of the Earth to Orbit Flight software, and ECLSS and PFMC, modules for Environmental Control and Life Support System and Pump Fan Motor Control, respectively.

Testing of Safety-Critical Software Embedded in an Artificial Heart

NASA Astrophysics Data System (ADS)

Cha, Sungdeok; Jeong, Sehun; Yoo, Junbeom; Kim, Young-Gab

Software is being used more frequently to control medical devices such as artificial heart or robotic surgery system. While much of software safety issues in such systems are similar to other safety-critical systems (e.g., nuclear power plants), domain-specific properties may warrant development of customized techniques to demonstrate fitness of the system on patients. In this paper, we report results of a preliminary analysis done on software controlling a Hybrid Ventricular Assist Device (H-VAD) developed by Korea Artificial Organ Centre (KAOC). It is a state-of-the-art artificial heart which completed animal testing phase. We performed software testing in in-vitro experiments and animal experiments. An abnormal behaviour, never detected during extensive in-vitro analysis and animal testing, was found.

Software architecture of INO340 telescope control system

NASA Astrophysics Data System (ADS)

Ravanmehr, Reza; Khosroshahi, Habib

2016-08-01

The software architecture plays an important role in distributed control system of astronomical projects because many subsystems and components must work together in a consistent and reliable way. We have utilized a customized architecture design approach based on "4+1 view model" in order to design INOCS software architecture. In this paper, after reviewing the top level INOCS architecture, we present the software architecture model of INOCS inspired by "4+1 model", for this purpose we provide logical, process, development, physical, and scenario views of our architecture using different UML diagrams and other illustrative visual charts. Each view presents INOCS software architecture from a different perspective. We finish the paper by science data operation of INO340 and the concluding remarks.

Guidelines for software inspections

NASA Technical Reports Server (NTRS)

1983-01-01

Quality control inspections are software problem finding procedures which provide defect removal as well as improvements in software functionality, maintenance, quality, and development and testing methodology is discussed. The many side benefits include education, documentation, training, and scheduling.

Computer implemented method, and apparatus for controlling a hand-held tool

NASA Technical Reports Server (NTRS)

Wagner, Kenneth William (Inventor); Taylor, James Clayton (Inventor)

1999-01-01

The invention described here in is a computer-implemented method and apparatus for controlling a hand-held tool. In particular, the control of a hand held tool is for the purpose of controlling the speed of a fastener interface mechanism and the torque applied to fasteners by the fastener interface mechanism of the hand-held tool and monitoring the operating parameters of the tool. The control is embodied in intool software embedded on a processor within the tool which also communicates with remote software. An operator can run the tool, or through the interaction of both software, operate the tool from a remote location, analyze data from a performance history recorded by the tool, and select various torque and speed parameters for each fastener.

Software control architecture for autonomous vehicles

NASA Astrophysics Data System (ADS)

Nelson, Michael L.; DeAnda, Juan R.; Fox, Richard K.; Meng, Xiannong

1999-07-01

The Strategic-Tactical-Execution Software Control Architecture (STESCA) is a tri-level approach to controlling autonomous vehicles. Using an object-oriented approach, STESCA has been developed as a generalization of the Rational Behavior Model (RBM). STESCA was initially implemented for the Phoenix Autonomous Underwater Vehicle (Naval Postgraduate School -- Monterey, CA), and is currently being implemented for the Pioneer AT land-based wheeled vehicle. The goals of STESCA are twofold. First is to create a generic framework to simplify the process of creating a software control architecture for autonomous vehicles of any type. Second is to allow for mission specification system by 'anyone' with minimal training to control the overall vehicle functionality. This paper describes the prototype implementation of STESCA for the Pioneer AT.

Air Traffic Control: Immature Software Acquisition Processes Increase FAA System Acquisition Risks

DOT National Transportation Integrated Search

1997-03-01

The General Accounting Office (GAO) at the request of Congress reviewed (1) : the maturity of Federal Aviation Administration's (FAA's) Air Traffic Control : (ATC) modernization software acquisition processes, and (2) the steps/actions : FAA has unde...

Promising More Information

NASA Technical Reports Server (NTRS)

2003-01-01

When NASA needed a real-time, online database system capable of tracking documentation changes in its propulsion test facilities, engineers at Stennis Space Center joined with ECT International, of Brookfield, Wisconsin, to create a solution. Through NASA's Dual-Use Program, ECT developed Exdata, a software program that works within the company's existing Promise software. Exdata not only satisfied NASA s requirements, but also expanded ECT s commercial product line. Promise, ECT s primary product, is an intelligent software program with specialized functions for designing and documenting electrical control systems. An addon to AutoCAD software, Promis e generates control system schematics, panel layouts, bills of material, wire lists, and terminal plans. The drawing functions include symbol libraries, macros, and automatic line breaking. Primary Promise customers include manufacturing companies, utilities, and other organizations with complex processes to control.

Agile development approach for the observatory control software of the DAG 4m telescope

NASA Astrophysics Data System (ADS)

Güçsav, B. Bülent; ćoker, Deniz; Yeşilyaprak, Cahit; Keskin, Onur; Zago, Lorenzo; Yerli, Sinan K.

2016-08-01

Observatory Control Software for the upcoming 4m infrared telescope of DAG (Eastern Anatolian Observatory in Turkish) is in the beginning of its lifecycle. After the process of elicitation-validation of the initial requirements, we have been focused on preparation of a rapid conceptual design not only to see the big picture of the system but also to clarify the further development methodology. The existing preliminary designs for both software (including TCS and active optics control system) and hardware shall be presented here in brief to exploit the challenges the DAG software team has been facing with. The potential benefits of an agile approach for the development will be discussed depending on the published experience of the community and on the resources available to us.

Remote Software Application and Display Development

NASA Technical Reports Server (NTRS)

Sanders, Brandon T.

2014-01-01

The era of the shuttle program has come to an end, but only to give rise to newer and more exciting projects. Now is the time of the Orion spacecraft, a work of art designed to exceed all previous endeavors of man. NASA is exiting the time of exploration and is entering a new period, a period of pioneering. With this new mission, many of NASAs organizations must undergo a great deal of change and development to support the Orion missions. The Spaceport Command and Control System (SCCS) is the new system that will provide NASA the ability to launch rockets into orbit and thus control Orion and other spacecraft as the goal of populating Mars becomes ever increasingly tangible. Since the previous control system, Launch Processing System (LPS), was primarily designed to launch the shuttles, SCCS was needed as Kennedy Space Center (KSC) reorganized to a multiuser spaceport for commercial flights, providing a more versatile control over rockets. Within SCCS, is the Launch Control System (LCS), which is the remote software behind the command and monitoring of flight and ground system hardware. This internship at KSC has involved two main components in LCS, including Remote Software Application and Display development. The display environment provides a graphical user interface for an operator to view and see if any cautions are raised, while the remote applications are the backbone that communicate with hardware, and then relay the data back to the displays. These elements go hand in hand as they provide monitoring and control over hardware and software alike from the safety of the Launch Control Center. The remote software applications are written in Application Control Language (ACL), which must undergo unit testing to ensure data integrity. This paper describes both the implementation and writing of unit tests in ACL code for remote software applications, as well as the building of remote displays to be used in the Launch Control Center (LCC).

Reusable Rack Interface Controller Common Software for Various Science Research Racks on the International Space Station

NASA Technical Reports Server (NTRS)

Lu, George C.

2003-01-01

The purpose of the EXPRESS (Expedite the PRocessing of Experiments to Space Station) rack project is to provide a set of predefined interfaces for scientific payloads which allow rapid integration into a payload rack on International Space Station (ISS). VxWorks' was selected as the operating system for the rack and payload resource controller, primarily based on the proliferation of VME (Versa Module Eurocard) products. These products provide needed flexibility for future hardware upgrades to meet everchanging science research rack configuration requirements. On the International Space Station, there are multiple science research rack configurations, including: 1) Human Research Facility (HRF); 2) EXPRESS ARIS (Active Rack Isolation System); 3) WORF (Window Observational Research Facility); and 4) HHR (Habitat Holding Rack). The RIC (Rack Interface Controller) connects payloads to the ISS bus architecture for data transfer between the payload and ground control. The RIC is a general purpose embedded computer which supports multiple communication protocols, including fiber optic communication buses, Ethernet buses, EIA-422, Mil-Std-1553 buses, SMPTE (Society Motion Picture Television Engineers)-170M video, and audio interfaces to payloads and the ISS. As a cost saving and software reliability strategy, the Boeing Payload Software Organization developed reusable common software where appropriate. These reusable modules included a set of low-level driver software interfaces to 1553B. RS232, RS422, Ethernet buses, HRDL (High Rate Data Link), video switch functionality, telemetry processing, and executive software hosted on the FUC computer. These drivers formed the basis for software development of the HRF, EXPRESS, EXPRESS ARIS, WORF, and HHR RIC executable modules. The reusable RIC common software has provided extensive benefits, including: 1) Significant reduction in development flow time; 2) Minimal rework and maintenance; 3) Improved reliability; and 4) Overall reduction in software life cycle cost. Due to the limited number of crew hours available on ISS for science research, operational efficiency is a critical customer concern. The current method of upgrading RIC software is a time consuming process; thus, an improved methodology for uploading RIC software is currently under evaluation.

The Implementation of Satellite Control System Software Using Object Oriented Design

NASA Technical Reports Server (NTRS)

Anderson, Mark O.; Reid, Mark; Drury, Derek; Hansell, William; Phillips, Tom

1998-01-01

NASA established the Small Explorer (SMEX) program in 1988 to provide frequent opportunities for highly focused and relatively inexpensive space science missions that can be launched into low earth orbit by small expendable vehicles. The development schedule for each SMEX spacecraft was three years from start to launch. The SMEX program has produced five satellites; Solar Anomalous and Magnetospheric Particle Explorer (SAMPEX), Fast Auroral Snapshot Explorer (FAST), Submillimeter Wave Astronomy Satellite (SWAS), Transition Region and Coronal Explorer (TRACE) and Wide-Field Infrared Explorer (WIRE). SAMPEX and FAST are on-orbit, TRACE is scheduled to be launched in April of 1998, WIRE is scheduled to be launched in September of 1998, and SWAS is scheduled to be launched in January of 1999. In each of these missions, the Attitude Control System (ACS) software was written using a modular procedural design. Current program goals require complete spacecraft development within 18 months. This requirement has increased pressure to write reusable flight software. Object-Oriented Design (OOD) offers the constructs for developing an application that only needs modification for mission unique requirements. This paper describes the OOD that was used to develop the SMEX-Lite ACS software. The SMEX-Lite ACS is three-axis controlled, momentum stabilized, and is capable of performing sub-arc-minute pointing. The paper first describes the high level requirements which governed the architecture of the SMEX-Lite ACS software. Next, the context in which the software resides is explained. The paper describes the benefits of encapsulation, inheritance and polymorphism with respect to the implementation of an ACS software system. This paper will discuss the design of several software components that comprise the ACS software. Specifically, Object-Oriented designs are presented for sensor data processing, attitude control, attitude determination and failure detection. The paper addresses the benefits of the OOD versus a conventional procedural design. The final discussion in this paper will address the establishment of the ACS Foundation Class (AFC) Library. The AFC is a large software repository, requiring a minimal amount of code modifications to produce ACS software for future projects, saving production time and costs.

Spacelab user implementation assessment study. (Software requirements analysis). Volume 2: Technical report

NASA Technical Reports Server (NTRS)

1976-01-01

The engineering analyses and evaluation studies conducted for the Software Requirements Analysis are discussed. Included are the development of the study data base, synthesis of implementation approaches for software required by both mandatory onboard computer services and command/control functions, and identification and implementation of software for ground processing activities.

Towards a Controlled Vocabulary on Software Engineering Education

ERIC Educational Resources Information Center

Pizard, Sebastián; Vallespir, Diego

2017-01-01

Software engineering is the discipline that develops all the aspects of the production of software. Although there are guidelines about what topics to include in a software engineering curricula, it is usually unclear which are the best methods to teach them. In any science discipline the construction of a classification schema is a common…

Computer Software: Copyright and Licensing Considerations for Schools and Libraries. ERIC Digest.

ERIC Educational Resources Information Center

Reed, Mary Hutchings

This digest notes that the terms and conditions of computer software package license agreements control the use of software in schools and libraries, and examines the implications of computer software license agreements for classroom use and for library lending policies. Guidelines are provided for interpreting the Copyright Act, and insuring the…

Complexity, Systems, and Software

DTIC Science & Technology

2014-08-14

2014 Carnegie Mellon University Complexity, Systems, and Software Software Engineering Institute Carnegie Mellon University Pittsburgh, PA...this collection of information, including suggestions for reducing this burden, to Washington Headquarters Services , Directorate for Information...OMB control number. 1. REPORT DATE 29 OCT 2014 2. REPORT TYPE N/A 3. DATES COVERED 4. TITLE AND SUBTITLE Complexity, Systems, and Software

The validation by measurement theory of proposed object-oriented software metrics

NASA Technical Reports Server (NTRS)

Neal, Ralph D.

1994-01-01

Moving software development into the engineering arena requires controllability, and to control a process, it must be measurable. Measuring the process does no good if the product is not also measured, i.e., being the best at producing an inferior product does not define a quality process. Also, not every number extracted from software development is a valid measurement. A valid measurement only results when we are able to verify that the number is representative of the attribute that we wish to measure. Many proposed software metrics are used by practitioners without these metrics ever having been validated, leading to costly but often useless calculations. Several researchers have bemoaned the lack of scientific precision in much of the published software measurement work and have called for validation of software metrics by measurement theory. This dissertation applies measurement theory to validate fifty proposed object-oriented software metrics (Li and Henry, 1993; Chidamber and Kemerrer, 1994; Lorenz and Kidd, 1994).

Automated Translation of Safety Critical Application Software Specifications into PLC Ladder Logic

NASA Technical Reports Server (NTRS)

Leucht, Kurt W.; Semmel, Glenn S.

2008-01-01

The numerous benefits of automatic application code generation are widely accepted within the software engineering community. A few of these benefits include raising the abstraction level of application programming, shorter product development time, lower maintenance costs, and increased code quality and consistency. Surprisingly, code generation concepts have not yet found wide acceptance and use in the field of programmable logic controller (PLC) software development. Software engineers at the NASA Kennedy Space Center (KSC) recognized the need for PLC code generation while developing their new ground checkout and launch processing system. They developed a process and a prototype software tool that automatically translates a high-level representation or specification of safety critical application software into ladder logic that executes on a PLC. This process and tool are expected to increase the reliability of the PLC code over that which is written manually, and may even lower life-cycle costs and shorten the development schedule of the new control system at KSC. This paper examines the problem domain and discusses the process and software tool that were prototyped by the KSC software engineers.

Infusing Reliability Techniques into Software Safety Analysis

NASA Technical Reports Server (NTRS)

Shi, Ying

2015-01-01

Software safety analysis for a large software intensive system is always a challenge. Software safety practitioners need to ensure that software related hazards are completely identified, controlled, and tracked. This paper discusses in detail how to incorporate the traditional reliability techniques into the entire software safety analysis process. In addition, this paper addresses how information can be effectively shared between the various practitioners involved in the software safety analyses. The author has successfully applied the approach to several aerospace applications. Examples are provided to illustrate the key steps of the proposed approach.

Advanced Shutter Control for a Molecular Beam Epitaxy Reactor

DTIC Science & Technology

An open-source hardware and software-based shutter controller solution was developed that communicates over Ethernet with our original equipment...manufacturer (OEM) molecular beam epitaxy (MBE) reactor control software. An Arduino Mega microcontroller is the used for the brain of the shutter... controller , while a custom-designed circuit board distributes 24-V power to each of the 16 shutter solenoids available on the MBE. Using Ethernet

Proceedings of the Workshop on software tools for distributed intelligent control systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Herget, C.J.

1990-09-01

The Workshop on Software Tools for Distributed Intelligent Control Systems was organized by Lawrence Livermore National Laboratory for the United States Army Headquarters Training and Doctrine Command and the Defense Advanced Research Projects Agency. The goals of the workshop were to the identify the current state of the art in tools which support control systems engineering design and implementation, identify research issues associated with writing software tools which would provide a design environment to assist engineers in multidisciplinary control design and implementation, formulate a potential investment strategy to resolve the research issues and develop public domain code which can formmore » the core of more powerful engineering design tools, and recommend test cases to focus the software development process and test associated performance metrics. Recognizing that the development of software tools for distributed intelligent control systems will require a multidisciplinary effort, experts in systems engineering, control systems engineering, and compute science were invited to participate in the workshop. In particular, experts who could address the following topics were selected: operating systems, engineering data representation and manipulation, emerging standards for manufacturing data, mathematical foundations, coupling of symbolic and numerical computation, user interface, system identification, system representation at different levels of abstraction, system specification, system design, verification and validation, automatic code generation, and integration of modular, reusable code.« less

A hardware-software system for the automation of verification and calibration of oil metering units secondary equipment

NASA Astrophysics Data System (ADS)

Boyarnikov, A. V.; Boyarnikova, L. V.; Kozhushko, A. A.; Sekachev, A. F.

2017-08-01

In the article the process of verification (calibration) of oil metering units secondary equipment is considered. The purpose of the work is to increase the reliability and reduce the complexity of this process by developing a software and hardware system that provides automated verification and calibration. The hardware part of this complex carries out the commutation of the measuring channels of the verified controller and the reference channels of the calibrator in accordance with the introduced algorithm. The developed software allows controlling the commutation of channels, setting values on the calibrator, reading the measured data from the controller, calculating errors and compiling protocols. This system can be used for checking the controllers of the secondary equipment of the oil metering units in the automatic verification mode (with the open communication protocol) or in the semi-automatic verification mode (without it). The peculiar feature of the approach used is the development of a universal signal switch operating under software control, which can be configured for various verification methods (calibration), which allows to cover the entire range of controllers of metering units secondary equipment. The use of automatic verification with the help of a hardware and software system allows to shorten the verification time by 5-10 times and to increase the reliability of measurements, excluding the influence of the human factor.

Detailed design and first tests of the application software for the instrument control unit of Euclid-NISP

NASA Astrophysics Data System (ADS)

Ligori, S.; Corcione, L.; Capobianco, V.; Bonino, D.; Sirri, G.; Fornari, F.; Giacomini, F.; Patrizii, L.; Valenziano, L.; Travaglini, R.; Colodro, C.; Bortoletto, F.; Bonoli, C.; Chiarusi, T.; Margiotta, A.; Mauri, N.; Pasqualini, L.; Spurio, M.; Tenti, M.; Dal Corso, F.; Dusini, S.; Laudisio, F.; Sirignano, C.; Stanco, L.; Ventura, S.; Auricchio, N.; Balestra, A.; Franceschi, E.; Morgante, G.; Trifoglio, M.; Medinaceli, E.; Guizzo, G. P.; Debei, S.; Stephen, J. B.

2016-07-01

In this paper we describe the detailed design of the application software (ASW) of the instrument control unit (ICU) of NISP, the Near-Infrared Spectro-Photometer of the Euclid mission. This software is based on a real-time operating system (RTEMS) and will interface with all the subunits of NISP, as well as the command and data management unit (CDMU) of the spacecraft for telecommand and housekeeping management. We briefly review the main requirements driving the design and the architecture of the software that is approaching the Critical Design Review level. The interaction with the data processing unit (DPU), which is the intelligent subunit controlling the detector system, is described in detail, as well as the concept for the implementation of the failure detection, isolation and recovery (FDIR) algorithms. The first version of the software is under development on a Breadboard model produced by AIRBUS/CRISA. We describe the results of the tests and the main performances and budgets.

An experiment in software reliability

NASA Technical Reports Server (NTRS)

Dunham, J. R.; Pierce, J. L.

1986-01-01

The results of a software reliability experiment conducted in a controlled laboratory setting are reported. The experiment was undertaken to gather data on software failures and is one in a series of experiments being pursued by the Fault Tolerant Systems Branch of NASA Langley Research Center to find a means of credibly performing reliability evaluations of flight control software. The experiment tests a small sample of implementations of radar tracking software having ultra-reliability requirements and uses n-version programming for error detection, and repetitive run modeling for failure and fault rate estimation. The experiment results agree with those of Nagel and Skrivan in that the program error rates suggest an approximate log-linear pattern and the individual faults occurred with significantly different error rates. Additional analysis of the experimental data raises new questions concerning the phenomenon of interacting faults. This phenomenon may provide one explanation for software reliability decay.

Instrument control software requirement specification for Extremely Large Telescopes

NASA Astrophysics Data System (ADS)

Young, Peter J.; Kiekebusch, Mario J.; Chiozzi, Gianluca

2010-07-01

Engineers in several observatories are now designing the next generation of optical telescopes, the Extremely Large Telescopes (ELT). These are very complex machines that will host sophisticated astronomical instruments to be used for a wide range of scientific studies. In order to carry out scientific observations, a software infrastructure is required to orchestrate the control of the multiple subsystems and functions. This paper will focus on describing the considerations, strategies and main issues related to the definition and analysis of the software requirements for the ELT's Instrument Control System using modern development processes and modelling tools like SysML.

Precise control and animation creation over the DMD for projection-based applications

NASA Astrophysics Data System (ADS)

Koudsi, Badia

2014-03-01

Digital micromirror devices (DMDs) are used in a variety of display and projection applications to produce high resolution images, both static and animated. A common obstacle to working with DMDs in research and development applications is the steep learning curve required to obtain proficiency in programming the boards that control the behavior of the DMDs. This can discourage developers who wish to use DMDs in new or novel research and development applications which might benefit from their light-control properties. A new software package called Light Animator has been developed that provides a user friendly and more intuitive interface for controlling the DMD. The software allows users to address the micromirror array by the drawing and animation of objects in a style similar to that of commercial drawing programs. Sequences and animation are controlled by dividing the sequence into frames which the user can draw individually or the software can fill in for the user. Examples and descriptions of the software operation are described and operational performance measures are provided. Potential applications include 3D volumetric displays, a 3D scanner when combining the DMD with a CCD camera, and most any 2D application for which DMDs are currently used. The software's capabilities allow scientists to develop applications more easily and effectively.

Mystic: Implementation of the Static Dynamic Optimal Control Algorithm for High-Fidelity, Low-Thrust Trajectory Design

NASA Technical Reports Server (NTRS)

Whiffen, Gregory J.

2006-01-01

Mystic software is designed to compute, analyze, and visualize optimal high-fidelity, low-thrust trajectories, The software can be used to analyze inter-planetary, planetocentric, and combination trajectories, Mystic also provides utilities to assist in the operation and navigation of low-thrust spacecraft. Mystic will be used to design and navigate the NASA's Dawn Discovery mission to orbit the two largest asteroids, The underlying optimization algorithm used in the Mystic software is called Static/Dynamic Optimal Control (SDC). SDC is a nonlinear optimal control method designed to optimize both 'static variables' (parameters) and dynamic variables (functions of time) simultaneously. SDC is a general nonlinear optimal control algorithm based on Bellman's principal.

Towards an Open, Distributed Software Architecture for UxS Operations

NASA Technical Reports Server (NTRS)

Cross, Charles D.; Motter, Mark A.; Neilan, James H.; Qualls, Garry D.; Rothhaar, Paul M.; Tran, Loc; Trujillo, Anna C.; Allen, B. Danette

2015-01-01

To address the growing need to evaluate, test, and certify an ever expanding ecosystem of UxS platforms in preparation of cultural integration, NASA Langley Research Center's Autonomy Incubator (AI) has taken on the challenge of developing a software framework in which UxS platforms developed by third parties can be integrated into a single system which provides evaluation and testing, mission planning and operation, and out-of-the-box autonomy and data fusion capabilities. This software framework, named AEON (Autonomous Entity Operations Network), has two main goals. The first goal is the development of a cross-platform, extensible, onboard software system that provides autonomy at the mission execution and course-planning level, a highly configurable data fusion framework sensitive to the platform's available sensor hardware, and plug-and-play compatibility with a wide array of computer systems, sensors, software, and controls hardware. The second goal is the development of a ground control system that acts as a test-bed for integration of the proposed heterogeneous fleet, and allows for complex mission planning, tracking, and debugging capabilities. The ground control system should also be highly extensible and allow plug-and-play interoperability with third party software systems. In order to achieve these goals, this paper proposes an open, distributed software architecture which utilizes at its core the Data Distribution Service (DDS) standards, established by the Object Management Group (OMG), for inter-process communication and data flow. The design decisions proposed herein leverage the advantages of existing robotics software architectures and the DDS standards to develop software that is scalable, high-performance, fault tolerant, modular, and readily interoperable with external platforms and software.

A Requirements Analysis Model for Selection of Personal Computer (PC) software in Air Force Organizations

DTIC Science & Technology

1988-09-01

Institute of Technology Air University In Partial Fulfillment of the Requirements for the Degree of Master of Science in Systems Management Dexter R... management system software Diag/Prob Diagnosis and problem solving or problem finding GR Graphics software Int/Transp Interoperability and...language software Plan/D.S. Planning and decision support or decision making PM Program management software SC Systems for Command, Control, Communications

CrossTalk: The Journal of Defense Software Engineering. Volume 18, Number 9

DTIC Science & Technology

2005-09-01

2004. 12. Humphrey , Watts . Introduction to the Personal Software Process SM. Addison- Wesley 1997. 13. Humphrey , Watts . Introduction to the Team...Personal Software ProcessSM (PSPSM)is a software development process orig- inated by Watts Humphrey at the Software Engineering Institute (SEI) in the...meets its commitments and bring a sense of control and predictability into an apparently chaotic project.u References 1. Humphrey , Watts . Coaching

Using Automation to Improve the Flight Software Testing Process

NASA Technical Reports Server (NTRS)

ODonnell, James R., Jr.; Morgenstern, Wendy M.; Bartholomew, Maureen O.

2001-01-01

One of the critical phases in the development of a spacecraft attitude control system (ACS) is the testing of its flight software. The testing (and test verification) of ACS flight software requires a mix of skills involving software, knowledge of attitude control, and attitude control hardware, data manipulation, and analysis. The process of analyzing and verifying flight software test results often creates a bottleneck which dictates the speed at which flight software verification can be conducted. In the development of the Microwave Anisotropy Probe (MAP) spacecraft ACS subsystem, an integrated design environment was used that included a MAP high fidelity (HiFi) simulation, a central database of spacecraft parameters, a script language for numeric and string processing, and plotting capability. In this integrated environment, it was possible to automate many of the steps involved in flight software testing, making the entire process more efficient and thorough than on previous missions. In this paper, we will compare the testing process used on MAP to that used on other missions. The software tools that were developed to automate testing and test verification will be discussed, including the ability to import and process test data, synchronize test data and automatically generate HiFi script files used for test verification, and an automated capability for generating comparison plots. A summary of the benefits of applying these test methods on MAP will be given. Finally, the paper will conclude with a discussion of re-use of the tools and techniques presented, and the ongoing effort to apply them to flight software testing of the Triana spacecraft ACS subsystem.

The COMPASS Tokamak Plasma Control Software Performance

NASA Astrophysics Data System (ADS)

Valcarcel, Daniel F.; Neto, André; Carvalho, Ivo S.; Carvalho, Bernardo B.; Fernandes, Horácio; Sousa, Jorge; Janky, Filip; Havlicek, Josef; Beno, Radek; Horacek, Jan; Hron, Martin; Panek, Radomir

2011-08-01

The COMPASS tokamak has began operation at the IPP Prague in December 2008. A new control system has been built using an ATCA-based real-time system developed at IST Lisbon. The control software is implemented on top of the MARTe real-time framework attaining control cycles as short as 50 μs, with a jitter of less than 1 μs. The controlled parameters, important for the plasma performance, are the plasma current, position of the plasma current center, boundary shape and horizontal and vertical velocities. These are divided in two control cycles: slow at 500 μs and fast at 50 μs. The project has two phases. First, the software implements a digital controller, similar to the analog one used during the COMPASS-D operation in Culham. In the slow cycle, the plasma current and position are measured and controlled with PID and feedforward controllers, respectively, the shaping magnetic field is preprogrammed. The vertical instability and horizontal equilibrium are controlled with the faster 50-μs cycle PID controllers. The second phase will implement a plasma-shape reconstruction algorithm and controller, aiming at optimized plasma performance. The system was designed to be as modular as possible by breaking the functional requirements of the control system into several independent and specialized modules. This splitting enabled tuning the execution of each system part and to use the modules in a variety of applications with different time constraints. This paper presents the design and overall performance of the COMPASS control software.

An overview on real-time control schemes for wheeled mobile robot

NASA Astrophysics Data System (ADS)

Radzak, M. S. A.; Ali, M. A. H.; Sha’amri, S.; Azwan, A. R.

2018-04-01

The purpose of this paper is to review real-time control motion algorithms for wheeled mobile robot (WMR) when navigating in environment such as road. Its need a good controller to avoid collision with any disturbance and maintain a track error at zero level. The controllers are used with other aiding sensors to measure the WMR’s velocities, posture, and interference to estimate the required torque to be applied on the wheels of mobile robot. Four main categories for wheeled mobile robot control systems have been found in literature which are namely: Kinematic based controller, Dynamic based controllers, artificial intelligence based control system, and Active Force control. A MATLAB/Simulink software is the main software to simulate and implement the control system. The real-time toolbox in MATLAB/SIMULINK are used to receive/send data from sensors/to actuator with presence of disturbances, however others software such C, C++ and visual basic are rare to be used.

Alternatives for jet engine control

NASA Technical Reports Server (NTRS)

Sain, M. K.

1983-01-01

Tensor model order reduction, recursive tensor model identification, input design for tensor model identification, software development for nonlinear feedback control laws based upon tensors, and development of the CATNAP software package for tensor modeling, identification and simulation were studied. The last of these are discussed.

Integrating Software Modules For Robot Control

NASA Technical Reports Server (NTRS)

Volpe, Richard A.; Khosla, Pradeep; Stewart, David B.

1993-01-01

Reconfigurable, sensor-based control system uses state variables in systematic integration of reusable control modules. Designed for open-architecture hardware including many general-purpose microprocessors, each having own local memory plus access to global shared memory. Implemented in software as extension of Chimera II real-time operating system. Provides transparent computing mechanism for intertask communication between control modules and generic process-module architecture for multiprocessor realtime computation. Used to control robot arm. Proves useful in variety of other control and robotic applications.

Randomized comparative evaluation of endoscopic submucosal dissection self-learning software in France and Japan.

PubMed

Pioche, Mathieu; Rivory, Jérôme; Nishizawa, Toshihiro; Uraoka, Toshio; Touzet, Sandrine; O'Brien, Marc; Saurin, Jean-Christophe; Ponchon, Thierry; Denis, Angélique; Yahagi, Naohisa

2016-12-01

Background and study aim: Endoscopic submucosal dissection (ESD) is currently the reference method to achieve an en bloc resection for large lesions; however, the technique is difficult and risky, with a long learning curve. In order to reduce the morbidity, training courses that use animal models are recommended. Recently, self-learning software has been developed to assist students in their training. The aim of this study was to evaluate the impact of this tool on the ESD learning curve. Methods: A prospective, randomized, comparative study enrolled 39 students who were experienced in interventional endoscopy. Each student was randomized to one of two groups and performed 30 ESDs of 30 mm standardized lesions in a bovine colon model. The software group used the self-learning software whereas the control group only observed an ESD procedure video. The primary outcome was the rate of successful ESD procedures, defined as complete en bloc resection without any perforation and performed in less than 75 minutes. Results: A total of 39 students performed 1170 ESDs. Success was achieved in 404 (70.9 %) in the software group and 367 (61.2 %) in the control group ( P  = 0.03). Among the successful procedures, there were no significant differences between the software and control groups in terms of perforation rate (22 [4.0 %] vs. 29 [5.1 %], respectively; P  = 0.27) and mean (SD) procedure duration (34.1 [13.4] vs. 32.3 [14.0] minutes, respectively; P  = 0.52). For the 30th procedure, the rate of complete resection was superior in the software group (84.2 %) compared with the control group (50.0 %; P  = 0.01). Conclusion: ESD self-learning software was effective in improving the quality of resection compared with a standard teaching method using procedure videos. This result suggests the benefit of incorporating such software into teaching programs. © Georg Thieme Verlag KG Stuttgart · New York.

Laser velocimeter data acquisition system for the Langley 14- by 22-foot subsonic tunnel. Software reference guide version 3.3

NASA Technical Reports Server (NTRS)

Jumper, Judith K.

1994-01-01

The Laser Velocimeter Data Acquisition System (LVDAS) in the Langley 14- by 22-Foot Tunnel is controlled by a comprehensive software package. The software package was designed to control the data acquisition process during wind tunnel tests which employ a laser velocimeter measurement system. This report provides detailed explanations on how to configure and operate the LVDAS system to acquire laser velocimeter and static wind tunnel data.

A controlled experiment on the impact of software structure on maintainability

NASA Technical Reports Server (NTRS)

Rombach, Dieter H.

1987-01-01

The impact of software structure on maintainability aspects including comprehensibility, locality, modifiability, and reusability in a distributed system environment is studied in a controlled maintenance experiment involving six medium-size distributed software systems implemented in LADY (language for distributed systems) and six in an extended version of sequential PASCAL. For all maintenance aspects except reusability, the results were quantitatively given in terms of complexity metrics which could be automated. The results showed LADY to be better suited to the development of maintainable software than the extension of sequential PASCAL. The strong typing combined with high parametrization of units is suggested to improve the reusability of units in LADY.

Mission planning, mission analysis and software formulation. Level C requirements for the shuttle mission control center orbital guidance software

NASA Technical Reports Server (NTRS)

Langston, L. J.

1976-01-01

The formulation of Level C requirements for guidance software was reported. Requirements for a PEG supervisor which controls all input/output interfaces with other processors and determines which PEG mode is to be utilized were studied in detail. A description of the two guidance modes for which Level C requirements have been formulated was presented. Functions required for proper execution of the guidance software were defined. The requirements for a navigation function that is used in the prediction logic of PEG mode 4 were discussed. It is concluded that this function is extracted from the current navigation FSSR.

The Environmental Control and Life Support System (ECLSS) advanced automation project

NASA Technical Reports Server (NTRS)

Dewberry, Brandon S.; Carnes, Ray

1990-01-01

The objective of the environmental control and life support system (ECLSS) Advanced Automation Project is to influence the design of the initial and evolutionary Space Station Freedom Program (SSFP) ECLSS toward a man-made closed environment in which minimal flight and ground manpower is needed. Another objective includes capturing ECLSS design and development knowledge future missions. Our approach has been to (1) analyze the SSFP ECLSS, (2) envision as our goal a fully automated evolutionary environmental control system - an augmentation of the baseline, and (3) document the advanced software systems, hooks, and scars which will be necessary to achieve this goal. From this analysis, prototype software is being developed, and will be tested using air and water recovery simulations and hardware subsystems. In addition, the advanced software is being designed, developed, and tested using automation software management plan and lifecycle tools. Automated knowledge acquisition, engineering, verification and testing tools are being used to develop the software. In this way, we can capture ECLSS development knowledge for future use develop more robust and complex software, provide feedback to the knowledge based system tool community, and ensure proper visibility of our efforts.

Continuous integration and quality control for scientific software

NASA Astrophysics Data System (ADS)

Neidhardt, A.; Ettl, M.; Brisken, W.; Dassing, R.

2013-08-01

Modern software has to be stable, portable, fast and reliable. This is going to be also more and more important for scientific software. But this requires a sophisticated way to inspect, check and evaluate the quality of source code with a suitable, automated infrastructure. A centralized server with a software repository and a version control system is one essential part, to manage the code basis and to control the different development versions. While each project can be compiled separately, the whole code basis can also be compiled with one central “Makefile”. This is used to create automated, nightly builds. Additionally all sources are inspected automatically with static code analysis and inspection tools, which check well-none error situations, memory and resource leaks, performance issues, or style issues. In combination with an automatic documentation generator it is possible to create the developer documentation directly from the code and the inline comments. All reports and generated information are presented as HTML page on a Web server. Because this environment increased the stability and quality of the software of the Geodetic Observatory Wettzell tremendously, it is now also available for scientific communities. One regular customer is already the developer group of the DiFX software correlator project.

An Operations Management System for the Space Station

NASA Astrophysics Data System (ADS)

Rosenthal, H. G.

1986-09-01

This paper presents an overview of the conceptual design of an integrated onboard Operations Management System (OMS). Both hardware and software concepts are presented and the integrated space station network is discussed. It is shown that using currently available software technology, an integrated software solution for Space Station management and control, implemented with OMS software, is feasible.

The New Cloud Absorption Radiometer (CAR) Software: One Model for NASA Remote Sensing Virtual Instruments

NASA Technical Reports Server (NTRS)

Roth, Don J.; Rapchun, David A.; Jones, Hollis H.

2001-01-01

The Cloud Absorption Radiometer (CAR) instrument has been the most frequently used airborne instrument built in-house at NASA Goddard Space Flight Center, having flown scientific research missions on-board various aircraft to many locations in the United States, Azores, Brazil, and Kuwait since 1983. The CAR instrument is capable of measuring scattered light by clouds in fourteen spectral bands in UV, visible and near-infrared region. This document describes the control, data acquisition, display, and file storage software for the new version of CAR. This software completely replaces the prior CAR Data System and Control Panel with a compact and robust virtual instrument computer interface. Additionally, the instrument is now usable for the first time for taking data in an off-aircraft mode. The new instrument is controlled via a LabVIEW v5. 1.1-developed software interface that utilizes, (1) serial port writes to write commands to the controller module of the instrument, and (2) serial port reads to acquire data from the controller module of the instrument. Step-by-step operational procedures are provided in this document. A suite of other software programs has been developed to complement the actual CAR virtual instrument. These programs include: (1) a simulator mode that allows pretesting of new features that might be added in the future, as well as demonstrations to CAR customers, and development at times when the instrument/hardware is off-location, and (2) a post-experiment data viewer that can be used to view all segments of individual data cycles and to locate positions where 'start' and stop' byte sequences were incorrectly formulated by the instrument controller. The CAR software described here is expected to be the basis for CAR operation for many missions and many years to come.

Real Time Control of the SSC String Magnets

NASA Astrophysics Data System (ADS)

Calvo, O.; Flora, R.; MacPherson, M.

1987-08-01

The system described in this paper, called SECAR, was designed to control the excitation of a test string of magnets for the proposed Superconducting Super Collider (SSC) and will be used to upgrade the present Tevatron Excitation, Control and Regulation (TECAR) hardware and software . It resides in a VME crate and is controlled by a 68020/68881 based CPU running the application software under a real time operating system named VRTX.

Real time control of the SSC string magnets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Calvo, O.; Flora, R.; MacPherson, M.

1987-08-01

The system described in this paper, called SECAR, was designed to control the excitation of a test string of magnets for the proposed Superconducting Super Collider (SSC) and will be used to upgrade the present Tevatron Excitation, Control and Regulation (TECAR) hardware and software. It resides in a VME orate and is controlled by a 68020/68881 based CPU running the application software under a real time operating system named VRTX.

A software architecture for hard real-time execution of automatically synthesized plans or control laws

NASA Technical Reports Server (NTRS)

Schoppers, Marcel

1994-01-01

The design of a flexible, real-time software architecture for trajectory planning and automatic control of redundant manipulators is described. Emphasis is placed on a technique of designing control systems that are both flexible and robust yet have good real-time performance. The solution presented involves an artificial intelligence algorithm that dynamically reprograms the real-time control system while planning system behavior.

Combat Vehicle Command and Control System Architecture Overview

DTIC Science & Technology

1994-10-01

inserted in the software. • Interactive interface displays and controls were prepared using rapidly prototyped software and were retained at the MWTB for...being simulated "* controls , sensor displays, and out-the-window displays for the crew "* computer image generators (CIGs) for out-the-window and...black hot viewing modes. The commander may access a number of capabilities of the CITV simulation, described below, from controls located around the

Research on an expert system for database operation of simulation-emulation math models. Volume 1, Phase 1: Results

NASA Technical Reports Server (NTRS)

Kawamura, K.; Beale, G. O.; Schaffer, J. D.; Hsieh, B. J.; Padalkar, S.; Rodriguez-Moscoso, J. J.

1985-01-01

The results of the first phase of Research on an Expert System for Database Operation of Simulation/Emulation Math Models, is described. Techniques from artificial intelligence (AI) were to bear on task domains of interest to NASA Marshall Space Flight Center. One such domain is simulation of spacecraft attitude control systems. Two related software systems were developed to and delivered to NASA. One was a generic simulation model for spacecraft attitude control, written in FORTRAN. The second was an expert system which understands the usage of a class of spacecraft attitude control simulation software and can assist the user in running the software. This NASA Expert Simulation System (NESS), written in LISP, contains general knowledge about digital simulation, specific knowledge about the simulation software, and self knowledge.

MOLECULAR IMAGING REVEALS RAPID REDUCTION OF ENDOTHELIAL ACTIVATION IN EARLY ATHEROSCLEROSIS WITH APOCYNIN INDEPENDENT OF ANTI-OXIDATIVE PROPERTIES

PubMed Central

Khanicheh, Elham; Qi, Yue; Xie, Aris; Mitterhuber, Martina; Xu, Lifen; Mochizuki, Michika; Daali, Youssef; Jaquet, Vincent; Krause, Karl-Heinz; Ruggeri, Zaverio M.; Kuster, Gabriela M.; Lindner, Jonathan R.; Kaufmann, Beat A.

2013-01-01

OBJECTIVE Anti-oxidative drugs continue to be developed for the treatment of atherosclerosis. Apocynin is an NADPH-oxidase-inhibitor with anti-inflammatory properties. We used contrast enhanced ultrasound (CEU) molecular imaging to assess whether short-term apocynin therapy in atherosclerosis reduces vascular oxidative stress and endothelial activation APPROACH AND RESULTS Genetically-modified mice with early atherosclerosis were studied at baseline and after 7 days of therapy with apocynin (4mg/kg/d I.P.) or saline. CEU molecular imaging of the aorta was performed with microbubbles targeted to vascular cell adhesion molecule 1 (VCAM-1; MBV), to platelet GPIbα (MBPl), and control microbubbles (MBCtr). Aortic VCAM-1 was measured using Western Blot. Aortic ROS generation was measured using a lucigenin assay. Hydroethidine (HE) oxidation was used to assess aortic superoxide generation. Baseline signal for MBV (1.3±0.3 A.U.) and MBPl (1.5±0.5 A.U.) was higher than for MBCtr (0.5±0.2 A.U., p<0.01). In saline-treated animals, signal did not significantly change for any microbubble agent whereas short-term apocynin significantly (p<0.05) reduced VCAM-1 and platelet signal (MBV: 0.3±0.1, MBPl: 0.4±0.1 MBCtr: 0.3±0.2 A.U., p=0.6 between agents). Apocynin reduced aortic VCAM-1 expression by 50% (p<0.05). However, apocynin therapy did not reduce either ROS content, superoxide generation, or macrophage content. CONCLUSIONS Short-term treatment with apocynin in atherosclerosis reduces endothelial cell adhesion molecule expression. This change in endothelial phenotype can be detected by molecular imaging before any measurable decrease in macrophage content, and is not associated with a detectable change in oxidative burden. PMID:23908248

Autonomous Performance Monitoring System: Monitoring and Self-Tuning (MAST)

NASA Technical Reports Server (NTRS)

Peterson, Chariya; Ziyad, Nigel A.

2000-01-01

Maintaining the long-term performance of software onboard a spacecraft can be a major factor in the cost of operations. In particular, the task of controlling and maintaining a future mission of distributed spacecraft will undoubtedly pose a great challenge, since the complexity of multiple spacecraft flying in formation grows rapidly as the number of spacecraft in the formation increases. Eventually, new approaches will be required in developing viable control systems that can handle the complexity of the data and that are flexible, reliable and efficient. In this paper we propose a methodology that aims to maintain the accuracy of flight software, while reducing the computational complexity of software tuning tasks. The proposed Monitoring and Self-Tuning (MAST) method consists of two parts: a flight software monitoring algorithm and a tuning algorithm. The dependency on the software being monitored is mostly contained in the monitoring process, while the tuning process is a generic algorithm independent of the detailed knowledge on the software. This architecture will enable MAST to be applicable to different onboard software controlling various dynamics of the spacecraft, such as attitude self-calibration, and formation control. An advantage of MAST over conventional techniques such as filter or batch least square is that the tuning algorithm uses machine learning approach to handle uncertainty in the problem domain, resulting in reducing over all computational complexity. The underlying concept of this technique is a reinforcement learning scheme based on cumulative probability generated by the historical performance of the system. The success of MAST will depend heavily on the reinforcement scheme used in the tuning algorithm, which guarantees the tuning solutions exist.

Traffic-Light-Preemption Vehicle-Transponder Software Module

NASA Technical Reports Server (NTRS)

Bachelder, Aaron; Foster, Conrad

2005-01-01

A prototype wireless data-communication and control system automatically modifies the switching of traffic lights to give priority to emergency vehicles. The system, which was reported in several NASA Tech Briefs articles at earlier stages of development, includes a transponder on each emergency vehicle, a monitoring and control unit (an intersection controller) at each intersection equipped with traffic lights, and a central monitoring subsystem. An essential component of the system is a software module executed by a microcontroller in each transponder. This module integrates and broadcasts data on the position, velocity, acceleration, and emergency status of the vehicle. The position, velocity, and acceleration data are derived partly from the Global Positioning System, partly from deductive reckoning, and partly from a diagnostic computer aboard the vehicle. The software module also monitors similar broadcasts from other vehicles and from intersection controllers, informs the driver of which intersections it controls, and generates visible and audible alerts to inform the driver of any other emergency vehicles that are close enough to create a potential hazard. The execution of the software module can be monitored remotely and the module can be upgraded remotely and, hence, automatically

Application of AI methods to aircraft guidance and control

NASA Technical Reports Server (NTRS)

Hueschen, Richard M.; Mcmanus, John W.

1988-01-01

A research program for integrating artificial intelligence (AI) techniques with tools and methods used for aircraft flight control system design, development, and implementation is discussed. The application of the AI methods for the development and implementation of the logic software which operates with the control mode panel (CMP) of an aircraft is presented. The CMP is the pilot control panel for the automatic flight control system of a commercial-type research aircraft of Langley Research Center's Advanced Transport Operating Systems (ATOPS) program. A mouse-driven color-display emulation of the CMP, which was developed with AI methods and used to test the AI software logic implementation, is discussed. The operation of the CMP was enhanced with the addition of a display which was quickly developed with AI methods. The display advises the pilot of conditions not satisfied when a mode does not arm or engage. The implementation of the CMP software logic has shown that the time required to develop, implement, and modify software systems can be significantly reduced with the use of the AI methods.

SPOT4 Operational Control Center (CMP)

NASA Technical Reports Server (NTRS)

Zaouche, G.

1993-01-01

CNES(F) is responsible for the development of a new generation of Operational Control Center (CMP) which will operate the new heliosynchronous remote sensing satellite (SPOT4). This Operational Control Center takes large benefit from the experience of the first generation of control center and from the recent advances in computer technology and standards. The CMP is designed for operating two satellites all the same time with a reduced pool of controllers. The architecture of this CMP is simple, robust, and flexible, since it is based on powerful distributed workstations interconnected through an Ethernet LAN. The application software uses modern and formal software engineering methods, in order to improve quality and reliability, and facilitate maintenance. This software is table driven so it can be easily adapted to other operational needs. Operation tasks are automated to the maximum extent, so that it could be possible to operate the CMP automatically with very limited human interference for supervision and decision making. This paper provides an overview of the SPOTS mission and associated ground segment. It also details the CMP, its functions, and its software and hardware architecture.

A generic testbed for the design of plasma spectrometer control software with application to the THOR-CSW solar wind instrument

NASA Astrophysics Data System (ADS)

De Keyser, Johan; Lavraud, Benoit; Neefs, Eddy; Berkenbosch, Sophie; Beeckman, Bram; Maggiolo, Romain; Gamby, Emmanuel; Fedorov, Andrei; Baruah, Rituparna; Wong, King-Wah; Amoros, Carine; Mathon, Romain; Génot, Vincent; Marcucci, Federica; Brienza, Daniele

2017-04-01

Modern plasma spectrometers require intelligent software that is able to exploit their capabilities to the fullest. While the low-level control of the instrument and basic tasks such as performing the basic measurement, temperature control, and production of housekeeping data are to be done by software that is executed on an FPGA and/or processor inside the instrument, higher level tasks such as control of measurement sequences, on-board moment calculation, beam tracking decisions, and data compression, may be performed by the instrument or in the payload data processing unit. Such design decisions, as well as an assessment of the workload on the different processing components, require early prototyping. We have developed a generic simulation testbed for the design of plasma spectrometer control software that allows an early evaluation of the level of resources that is needed at each level. Early prototyping can pinpoint bottlenecks in the design allowing timely remediation. We have applied this tool to the THOR Cold Solar Wind (CSW) plasma spectrometer. Some examples illustrating the usefulness of the tool are given.

Executable assertions and flight software

NASA Technical Reports Server (NTRS)

Mahmood, A.; Andrews, D. M.; Mccluskey, E. J.

1984-01-01

Executable assertions are used to test flight control software. The techniques used for testing flight software; however, are different from the techniques used to test other kinds of software. This is because of the redundant nature of flight software. An experimental setup for testing flight software using executable assertions is described. Techniques for writing and using executable assertions to test flight software are presented. The error detection capability of assertions is studied and many examples of assertions are given. The issues of placement and complexity of assertions and the language features to support efficient use of assertions are discussed.

SWiFT Software Quality Assurance Plan.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berg, Jonathan Charles

This document describes the software development practice areas and processes which contribute to the ability of SWiFT software developers to provide quality software. These processes are designed to satisfy the requirements set forth by the Sandia Software Quality Assurance Program (SSQAP). APPROVALS SWiFT Software Quality Assurance Plan (SAND2016-0765) approved by: Department Manager SWiFT Site Lead Dave Minster (6121) Date Jonathan White (6121) Date SWiFT Controls Engineer Jonathan Berg (6121) Date CHANGE HISTORY Issue Date Originator(s) Description A 2016/01/27 Jon Berg (06121) Initial release of the SWiFT Software Quality Assurance Plan

GenePRIMP: A software quality control tool

ScienceCinema

Amrita Pati

2017-12-09

Amrita Pati of the DOE Joint Genome Institute's Genome Biology group describes the software tool GenePRIMP and how it fits into the quality control pipeline for microbial genomics. Further details regarding GenePRIMP appear in a paper published online May 2, 2010 in Nature Methods.

Second generation heliostat development for solar central receiver systems. Volume 4, appendices F-J: Control software test results manufacturing pile installation pile coatings

NASA Astrophysics Data System (ADS)

1981-03-01

Support documentation for a second generation heliostat project is presented. Flowcharts of control software are included. Numerical and graphic test results are provided. Project management information is also provided.

Software structure for Vega/Chara instrument

NASA Astrophysics Data System (ADS)

Clausse, J.-M.

2008-07-01

VEGA (Visible spEctroGraph and polArimeter) is one of the focal instruments of the CHARA array at Mount Wilson near Los Angeles. Its control system is based on techniques developed on the GI2T interferometer (Grand Interferometre a 2 Telescopes) and on the SIRIUS fibered hyper telescope testbed at OCA (Observatoire de la Cote d'Azur). This article describes the software and electronics architecture of the instrument. It is based on local network architecture and uses also Virtual Private Network connections. The server part is based on Windows XP (VC++). The control software is on Linux (C, GTK). For the control of the science detector and the fringe tracking systems, distributed API use real-time techniques. The control software gathers all the necessary informations of the instrument. It allows an automatic management of the instrument by using an original task scheduler. This architecture intends to drive the instrument from remote sites, such as our institute in South of France.

An Integrated System for Wildlife Sensing

DTIC Science & Technology

2014-08-14

design requirement. “Sensor Controller” software. A custom Sensor Controller application was developed for the Android device in order to collect...and log readings from that device’s sensors. “Camera Controller” software. A custom Camera Controller application was developed for the Android device...into 2 separate Android applications (Figure 4). The Sensor Controller logs readings periodically from the Android device’s organic sensors, and

Generating Safety-Critical PLC Code From a High-Level Application Software Specification

NASA Technical Reports Server (NTRS)

2008-01-01

The benefits of automatic-application code generation are widely accepted within the software engineering community. These benefits include raised abstraction level of application programming, shorter product development time, lower maintenance costs, and increased code quality and consistency. Surprisingly, code generation concepts have not yet found wide acceptance and use in the field of programmable logic controller (PLC) software development. Software engineers at Kennedy Space Center recognized the need for PLC code generation while developing the new ground checkout and launch processing system, called the Launch Control System (LCS). Engineers developed a process and a prototype software tool that automatically translates a high-level representation or specification of application software into ladder logic that executes on a PLC. All the computer hardware in the LCS is planned to be commercial off the shelf (COTS), including industrial controllers or PLCs that are connected to the sensors and end items out in the field. Most of the software in LCS is also planned to be COTS, with only small adapter software modules that must be developed in order to interface between the various COTS software products. A domain-specific language (DSL) is a programming language designed to perform tasks and to solve problems in a particular domain, such as ground processing of launch vehicles. The LCS engineers created a DSL for developing test sequences of ground checkout and launch operations of future launch vehicle and spacecraft elements, and they are developing a tabular specification format that uses the DSL keywords and functions familiar to the ground and flight system users. The tabular specification format, or tabular spec, allows most ground and flight system users to document how the application software is intended to function and requires little or no software programming knowledge or experience. A small sample from a prototype tabular spec application is shown.

Software Quality Assurance and Controls Standard

DTIC Science & Technology

2010-04-27

Software Quality Assurance d C t l St d dan on ro s an ar Sue Carroll Principal Software Quality Analyst, SAS John Wal z VP Technology and...for Information Operations and Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington VA 22202-4302. Respondents should be aware that...Cycle (SLC) process? • What is in a SQA Process? • Where are SQA Controls? • What is the SQA standards history? Wh t i h i i SQA?• a s c ang ng n

Achieving design reuse: a case study

NASA Astrophysics Data System (ADS)

Young, Peter J.; Nielsen, Jon J.; Roberts, William H.; Wilson, Greg M.

2008-08-01

The RSAA CICADA data acquisition and control software package uses an object-oriented approach to model astronomical instrumentation and a layered architecture for implementation. Emphasis has been placed on building reusable C++ class libraries and on the use of attribute/value tables for dynamic configuration. This paper details how the approach has been successfully used in the construction of the instrument control software for the Gemini NIFS and GSAOI instruments. The software is again being used for the new RSAA SkyMapper and WiFeS instruments.

Use of software engineering techniques in the design of the ALEPH data acquisition system

NASA Astrophysics Data System (ADS)

Charity, T.; McClatchey, R.; Harvey, J.

1987-08-01

The SASD methodology is being used to provide a rigorous design framework for various components of the ALEPH data acquisition system. The Entity-Relationship data model is used to describe the layout and configuration of the control and acquisition systems and detector components. State Transition Diagrams are used to specify control applications such as run control and resource management and Data Flow Diagrams assist in decomposing software tasks and defining interfaces between processes. These techniques encourage rigorous software design leading to enhanced functionality and reliability. Improved documentation and communication ensures continuity over the system life-cycle and simplifies project management.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, Mark A.; Bigelow, Matthew; Gilkey, Jeff C.

The Super Strypi Navigation, Guidance & Control Software is a real-time implementation of the navigation, guidance and control algorithms designed to deliver a payload to a desired orbit for the rail launched Super Strypi launch vehicle. The software contains all flight control algorithms required from pre-launch until orbital insertion. The flight sequencer module calls the NG&C functions at the appropriate times of flight. Additional functionality includes all the low level drivers and I/O for communicating to other systems within the launch vehicle and to the ground support equipment. The software is designed such that changes to the launch location andmore » desired orbit can be changed without recompiling the code.« less

Development of Ada language control software for the NASA power management and distribution test bed

NASA Technical Reports Server (NTRS)

Wright, Ted; Mackin, Michael; Gantose, Dave

1989-01-01

The Ada language software developed to control the NASA Lewis Research Center's Power Management and Distribution testbed is described. The testbed is a reduced-scale prototype of the electric power system to be used on space station Freedom. It is designed to develop and test hardware and software for a 20-kHz power distribution system. The distributed, multiprocessor, testbed control system has an easy-to-use operator interface with an understandable English-text format. A simple interface for algorithm writers that uses the same commands as the operator interface is provided, encouraging interactive exploration of the system.

Human performance interfaces in air traffic control.

PubMed

Chang, Yu-Hern; Yeh, Chung-Hsing

2010-01-01

This paper examines how human performance factors in air traffic control (ATC) affect each other through their mutual interactions. The paper extends the conceptual SHEL model of ergonomics to describe the ATC system as human performance interfaces in which the air traffic controllers interact with other human performance factors including other controllers, software, hardware, environment, and organisation. New research hypotheses about the relationships between human performance interfaces of the system are developed and tested on data collected from air traffic controllers, using structural equation modelling. The research result suggests that organisation influences play a more significant role than individual differences or peer influences on how the controllers interact with the software, hardware, and environment of the ATC system. There are mutual influences between the controller-software, controller-hardware, controller-environment, and controller-organisation interfaces of the ATC system, with the exception of the controller-controller interface. Research findings of this study provide practical insights in managing human performance interfaces of the ATC system in the face of internal or external change, particularly in understanding its possible consequences in relation to the interactions between human performance factors.

Robust Software Architecture for Robots

NASA Technical Reports Server (NTRS)

Aghazanian, Hrand; Baumgartner, Eric; Garrett, Michael

2009-01-01

Robust Real-Time Reconfigurable Robotics Software Architecture (R4SA) is the name of both a software architecture and software that embodies the architecture. The architecture was conceived in the spirit of current practice in designing modular, hard, realtime aerospace systems. The architecture facilitates the integration of new sensory, motor, and control software modules into the software of a given robotic system. R4SA was developed for initial application aboard exploratory mobile robots on Mars, but is adaptable to terrestrial robotic systems, real-time embedded computing systems in general, and robotic toys.

The 4MOST facility control software

NASA Astrophysics Data System (ADS)

Pramskiy, Alexander; Mandel, Holger; Rothmaier, Florian; Stilz, Ingo; Winkler, Roland; Hahn, Thomas

2016-07-01

The 4-m Multi-Object Spectrographic Telescope (4MOST) is one high-resolution (R 18000) and two lowresolution (R fi 5000) spectrographs covering the wavelength range between 390 and 950 nm. The spectrographs will be installed on ESO VISTA telescope and will be fed by approximately 2400 fibres. The instrument is capable to simultaneously obtain spectra of about 2400 objects distributed over an hexagonal field-of-view of four square degrees. This paper aims at giving an overview of the control software design, which is based on the standard ESO VLT software architecture and customised to fit the needs of the 4MOST instrument. In particular, the facility control software is intended to arrange the precise positioning of the fibres, to schedule and observe many surveys in parallel, and to combine the output from the three spectrographs. Moreover, 4MOST's software will include user-friendly graphical user interfaces that enable users to interact with the facility control system and to monitor all data-taking and calibration tasks of the instrument. A secondary guiding system will be implemented to correct for any fibre exure and thus to improve 4MOST's guiding performance. The large amount of fibres requires the custom design of data exchange to avoid performance issues. The observation sequences are designed to use spectrographs in parallel with synchronous points for data exchange between subsystems. In order to control hardware devices, Programmable Logic Controller (PLC) components will be used, the new standard for future instruments at ESO.

A near-infrared fluorescence-based surgical navigation system imaging software for sentinel lymph node detection

NASA Astrophysics Data System (ADS)

Ye, Jinzuo; Chi, Chongwei; Zhang, Shuang; Ma, Xibo; Tian, Jie

2014-02-01

Sentinel lymph node (SLN) in vivo detection is vital in breast cancer surgery. A new near-infrared fluorescence-based surgical navigation system (SNS) imaging software, which has been developed by our research group, is presented for SLN detection surgery in this paper. The software is based on the fluorescence-based surgical navigation hardware system (SNHS) which has been developed in our lab, and is designed specifically for intraoperative imaging and postoperative data analysis. The surgical navigation imaging software consists of the following software modules, which mainly include the control module, the image grabbing module, the real-time display module, the data saving module and the image processing module. And some algorithms have been designed to achieve the performance of the software, for example, the image registration algorithm based on correlation matching. Some of the key features of the software include: setting the control parameters of the SNS; acquiring, display and storing the intraoperative imaging data in real-time automatically; analysis and processing of the saved image data. The developed software has been used to successfully detect the SLNs in 21 cases of breast cancer patients. In the near future, we plan to improve the software performance and it will be extensively used for clinical purpose.

Using Utility Functions to Control a Distributed Storage System

DTIC Science & Technology

2008-05-01

Pinheiro et al. [2007] suggest this is not an accurate assumption. Nicola and Goyal [1990] examined correlated failures across multiversion software...F. and Goyal, A. (1990). Modeling of correlated failures and community error recovery in multiversion software. IEEE Transactions on Software

An Overview of U.S. Trends in Educational Software Design.

ERIC Educational Resources Information Center

Colvin, Linda B.

1989-01-01

Describes trends in educational software design in the United States for elementary and secondary education. Highlights include user-friendly software; learner control; interfacing the computer with other media, including television, telecommunications networks, and optical disk technology; microworlds; graphics; word processing; database…

Florida alternative NTCIP testing software (ANTS) for actuated signal controllers.

DOT National Transportation Integrated Search

2009-01-01

The scope of this research project did include the development of a software tool to test devices for NTCIP compliance. Development of the Florida Alternative NTCIP Testing Software (ANTS) was developed by the research team due to limitations found w...

Cybernetic Control of an Electrochemical Repertoire.

ERIC Educational Resources Information Center

He, Peixin; And Others

1982-01-01

Describes major features of a computer-operated, cybernetic potentiostat and the development, design, and operation of the software in ROM. The instrument contains control circuitry and software making it compatible with the static mercury drop electrode produced by EG&G Princeton Applied Research Corporation. Sample results using the…

14 CFR 35.23 - Propeller control system.

Code of Federal Regulations, 2013 CFR

2013-01-01

... between operating modes, performs the functions defined by the applicant throughout the declared operating... system imbedded software must be designed and implemented by a method approved by the Administrator that... software errors. (d) The propeller control system must be designed and constructed so that the failure or...

14 CFR 35.23 - Propeller control system.

Code of Federal Regulations, 2012 CFR

2012-01-01

... between operating modes, performs the functions defined by the applicant throughout the declared operating... system imbedded software must be designed and implemented by a method approved by the Administrator that... software errors. (d) The propeller control system must be designed and constructed so that the failure or...

14 CFR 35.23 - Propeller control system.

Code of Federal Regulations, 2014 CFR

2014-01-01

... between operating modes, performs the functions defined by the applicant throughout the declared operating... system imbedded software must be designed and implemented by a method approved by the Administrator that... software errors. (d) The propeller control system must be designed and constructed so that the failure or...

Preliminary input to the space shuttle reaction control subsystem failure detection and identification software requirements (uncontrolled)

NASA Technical Reports Server (NTRS)

Bergmann, E.

1976-01-01

The current baseline method and software implementation of the space shuttle reaction control subsystem failure detection and identification (RCS FDI) system is presented. This algorithm is recommended for conclusion in the redundancy management (RM) module of the space shuttle guidance, navigation, and control system. Supporting software is presented, and recommended for inclusion in the system management (SM) and display and control (D&C) systems. RCS FDI uses data from sensors in the jets, in the manifold isolation valves, and in the RCS fuel and oxidizer storage tanks. A list of jet failures and fuel imbalance warnings is generated for use by the jet selection algorithm of the on-orbit and entry flight control systems, and to inform the crew and ground controllers of RCS failure status. Manifold isolation valve close commands are generated in the event of failed on or leaking jets to prevent loss of large quantities of RCS fuel.

Customizing graphical user interface technology for spacecraft control centers

NASA Technical Reports Server (NTRS)

Beach, Edward; Giancola, Peter; Gibson, Steven; Mahmot, Ronald

1993-01-01

The Transportable Payload Operations Control Center (TPOCC) project is applying the latest in graphical user interface technology to the spacecraft control center environment. This project of the Mission Operations Division's (MOD) Control Center Systems Branch (CCSB) at NASA Goddard Space Flight Center (GSFC) has developed an architecture for control centers which makes use of a distributed processing approach and the latest in Unix workstation technology. The TPOCC project is committed to following industry standards and using commercial off-the-shelf (COTS) hardware and software components wherever possible to reduce development costs and to improve operational support. TPOCC's most successful use of commercial software products and standards has been in the development of its graphical user interface. This paper describes TPOCC's successful use and customization of four separate layers of commercial software products to create a flexible and powerful user interface that is uniquely suited to spacecraft monitoring and control.

A proven approach for more effective software development and maintenance

NASA Technical Reports Server (NTRS)

Pajerski, Rose; Hall, Dana; Sinclair, Craig

1994-01-01

Modern space flight mission operations and associated ground data systems are increasingly dependent upon reliable, quality software. Critical functions such as command load preparation, health and status monitoring, communications link scheduling and conflict resolution, and transparent gateway protocol conversion are routinely performed by software. Given budget constraints and the ever increasing capabilities of processor technology, the next generation of control centers and data systems will be even more dependent upon software across all aspects of performance. A key challenge now is to implement improved engineering, management, and assurance processes for the development and maintenance of that software; processes that cost less, yield higher quality products, and that self-correct for continual improvement evolution. The NASA Goddard Space Flight Center has a unique experience base that can be readily tapped to help solve the software challenge. Over the past eighteen years, the Software Engineering Laboratory within the code 500 Flight Dynamics Division has evolved a software development and maintenance methodology that accommodates the unique characteristics of an organization while optimizing and continually improving the organization's software capabilities. This methodology relies upon measurement, analysis, and feedback much analogous to that of control loop systems. It is an approach with a time-tested track record proven through repeated applications across a broad range of operational software development and maintenance projects. This paper describes the software improvement methodology employed by the Software Engineering Laboratory, and how it has been exploited within the Flight Dynamics Division with GSFC Code 500. Examples of specific improvement in the software itself and its processes are presented to illustrate the effectiveness of the methodology. Finally, the initial findings are given when this methodology was applied across the mission operations and ground data systems software domains throughout Code 500.

Power and sample size for multivariate logistic modeling of unmatched case-control studies.

PubMed

Gail, Mitchell H; Haneuse, Sebastien

2017-01-01

Sample size calculations are needed to design and assess the feasibility of case-control studies. Although such calculations are readily available for simple case-control designs and univariate analyses, there is limited theory and software for multivariate unconditional logistic analysis of case-control data. Here we outline the theory needed to detect scalar exposure effects or scalar interactions while controlling for other covariates in logistic regression. Both analytical and simulation methods are presented, together with links to the corresponding software.

Multirate Flutter Suppression System Design for the Benchmark Active Controls Technology Wing. Part 2; Methodology Application Software Toolbox

NASA Technical Reports Server (NTRS)

Mason, Gregory S.; Berg, Martin C.; Mukhopadhyay, Vivek

2002-01-01

To study the effectiveness of various control system design methodologies, the NASA Langley Research Center initiated the Benchmark Active Controls Project. In this project, the various methodologies were applied to design a flutter suppression system for the Benchmark Active Controls Technology (BACT) Wing. This report describes the user's manual and software toolbox developed at the University of Washington to design a multirate flutter suppression control law for the BACT wing.

Microprocessor control system for 200-kilowatt Mod-OA wind turbines

NASA Technical Reports Server (NTRS)

Nyland, T. W.; Birchenough, A. G.

1982-01-01

The microprocessor system and program used to control the operation of the 200-kW Mod-OA wind turbines is described. The system is programmed to begin startup and shutdown sequences automatically and to control yaw motion. Rotor speed and power output are controlled with integral and proportional control of the blade pitch angle. Included in the report are a description of the hardware and a discussion of the software programming technique. A listing of the PL/M software program is given.

SPLASSH: Open source software for camera-based high-speed, multispectral in-vivo optical image acquisition

PubMed Central

Sun, Ryan; Bouchard, Matthew B.; Hillman, Elizabeth M. C.

2010-01-01

Camera-based in-vivo optical imaging can provide detailed images of living tissue that reveal structure, function, and disease. High-speed, high resolution imaging can reveal dynamic events such as changes in blood flow and responses to stimulation. Despite these benefits, commercially available scientific cameras rarely include software that is suitable for in-vivo imaging applications, making this highly versatile form of optical imaging challenging and time-consuming to implement. To address this issue, we have developed a novel, open-source software package to control high-speed, multispectral optical imaging systems. The software integrates a number of modular functions through a custom graphical user interface (GUI) and provides extensive control over a wide range of inexpensive IEEE 1394 Firewire cameras. Multispectral illumination can be incorporated through the use of off-the-shelf light emitting diodes which the software synchronizes to image acquisition via a programmed microcontroller, allowing arbitrary high-speed illumination sequences. The complete software suite is available for free download. Here we describe the software’s framework and provide details to guide users with development of this and similar software. PMID:21258475

Dose Estimating Application Software Modification: Additional Function of a Size-Specific Effective Dose Calculator and Auto Exposure Control.

PubMed

Kobayashi, Masanao; Asada, Yasuki; Matsubara, Kosuke; Suzuki, Shouichi; Matsunaga, Yuta; Haba, Tomonobu; Kawaguchi, Ai; Daioku, Tomihiko; Toyama, Hiroshi; Kato, Ryoichi

2017-05-01

Adequate dose management during computed tomography is important. In the present study, the dosimetric application software ImPACT was added to a functional calculator of the size-specific dose estimate and was part of the scan settings for the auto exposure control (AEC) technique. This study aimed to assess the practicality and accuracy of the modified ImPACT software for dose estimation. We compared the conversion factors identified by the software with the values reported by the American Association of Physicists in Medicine Task Group 204, and we noted similar results. Moreover, doses were calculated with the AEC technique and a fixed-tube current of 200 mA for the chest-pelvis region. The modified ImPACT software could estimate each organ dose, which was based on the modulated tube current. The ability to perform beneficial modifications indicates the flexibility of the ImPACT software. The ImPACT software can be further modified for estimation of other doses. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Software Certification - Coding, Code, and Coders

NASA Technical Reports Server (NTRS)

Havelund, Klaus; Holzmann, Gerard J.

2011-01-01

We describe a certification approach for software development that has been adopted at our organization. JPL develops robotic spacecraft for the exploration of the solar system. The flight software that controls these spacecraft is considered to be mission critical. We argue that the goal of a software certification process cannot be the development of "perfect" software, i.e., software that can be formally proven to be correct under all imaginable and unimaginable circumstances. More realistically, the goal is to guarantee a software development process that is conducted by knowledgeable engineers, who follow generally accepted procedures to control known risks, while meeting agreed upon standards of workmanship. We target three specific issues that must be addressed in such a certification procedure: the coding process, the code that is developed, and the skills of the coders. The coding process is driven by standards (e.g., a coding standard) and tools. The code is mechanically checked against the standard with the help of state-of-the-art static source code analyzers. The coders, finally, are certified in on-site training courses that include formal exams.

The Software Management Environment (SME)

NASA Technical Reports Server (NTRS)

Valett, Jon D.; Decker, William; Buell, John

1988-01-01

The Software Management Environment (SME) is a research effort designed to utilize the past experiences and results of the Software Engineering Laboratory (SEL) and to incorporate this knowledge into a tool for managing projects. SME provides the software development manager with the ability to observe, compare, predict, analyze, and control key software development parameters such as effort, reliability, and resource utilization. The major components of the SME, the architecture of the system, and examples of the functionality of the tool are discussed.

Software engineering project management - A state-of-the-art report

NASA Technical Reports Server (NTRS)

Thayer, R. H.; Lehman, J. H.

1977-01-01

The management of software engineering projects in the aerospace industry was investigated. The survey assessed such features as contract type, specification preparation techniques, software documentation required by customers, planning and cost-estimating, quality control, the use of advanced program practices, software tools and test procedures, the education levels of project managers, programmers and analysts, work assignment, automatic software monitoring capabilities, design and coding reviews, production times, success rates, and organizational structure of the projects.

Software to Control and Monitor Gas Streams

NASA Technical Reports Server (NTRS)

Arkin, C.; Curley, Charles; Gore, Eric; Floyd, David; Lucas, Damion

2012-01-01

This software package interfaces with various gas stream devices such as pressure transducers, flow meters, flow controllers, valves, and analyzers such as a mass spectrometer. The software provides excellent user interfacing with various windows that provide time-domain graphs, valve state buttons, priority- colored messages, and warning icons. The user can configure the software to save as much or as little data as needed to a comma-delimited file. The software also includes an intuitive scripting language for automated processing. The configuration allows for the assignment of measured values or calibration so that raw signals can be viewed as usable pressures, flows, or concentrations in real time. The software is based on those used in two safety systems for shuttle processing and one volcanic gas analysis system. Mass analyzers typically have very unique applications and vary from job to job. As such, software available on the market is usually inadequate or targeted on a specific application (such as EPA methods). The goal was to develop powerful software that could be used with prototype systems. The key problem was to generalize the software to be easily and quickly reconfigurable. At Kennedy Space Center (KSC), the prior art consists of two primary methods. The first method was to utilize Lab- VIEW and a commercial data acquisition system. This method required rewriting code for each different application and only provided raw data. To obtain data in engineering units, manual calculations were required. The second method was to utilize one of the embedded computer systems developed for another system. This second method had the benefit of providing data in engineering units, but was limited in the number of control parameters.

Network, system, and status software enhancements for the autonomously managed electrical power system breadboard. Volume 1: Project summary

NASA Technical Reports Server (NTRS)

Mckee, James W.

1990-01-01

This volume (1 of 4) gives a summary of the original AMPS software system configuration, points out some of the problem areas in the original software design that this project is to address, and in the appendix collects all the bimonthly status reports. The purpose of AMPS is to provide a self reliant system to control the generation and distribution of power in the space station. The software in the AMPS breadboard can be divided into three levels: the operating environment software, the protocol software, and the station specific software. This project deals only with the operating environment software and the protocol software. The present station specific software will not change except as necessary to conform to new data formats.

Software Support during a Control Room Upgrade

DOE Office of Scientific and Technical Information (OSTI.GOV)

Michele Joyce; Michael Spata; Thomas Oren

2005-09-21

In 2004, after 14 years of accelerator operations and commissioning, Jefferson Lab renovated its main control room. Changes in technology and lessons learned during those 14 years drove the control room redesign in a new direction, one that optimizes workflow and makes critical information and controls available to everyone in the control room. Fundamental changes in a variety of software applications were required to facilitate the new operating paradigm. A critical component of the new control room design is a large-format video wall that is used to make a variety of operating information available to everyone in the room. Analogmore » devices such as oscilloscopes and function generators are now displayed on the video wall through two crosspoint switchers: one for analog signals and another for video signals. A new software GUI replaces manual configuration of the oscilloscopes and function generators and helps automate setup. Monitoring screens, customized for the video wall, now make important operating information visible to everyone, not just a single operator. New alarm handler software gives any operator, on any workstation, access to all alarm handler functionality, and multiple users can now contribute to a single electronic logbook entry. To further support the shift to distributed access and control, many applications have been redesigned to run on servers instead of on individual workstations.« less

Knowledge-based processing for aircraft flight control

NASA Technical Reports Server (NTRS)

Painter, John H.; Glass, Emily; Economides, Gregory; Russell, Paul

1994-01-01

This Contractor Report documents research in Intelligent Control using knowledge-based processing in a manner dual to methods found in the classic stochastic decision, estimation, and control discipline. Such knowledge-based control has also been called Declarative, and Hybid. Software architectures were sought, employing the parallelism inherent in modern object-oriented modeling and programming. The viewpoint adopted was that Intelligent Control employs a class of domain-specific software architectures having features common over a broad variety of implementations, such as management of aircraft flight, power distribution, etc. As much attention was paid to software engineering issues as to artificial intelligence and control issues. This research considered that particular processing methods from the stochastic and knowledge-based worlds are duals, that is, similar in a broad context. They provide architectural design concepts which serve as bridges between the disparate disciplines of decision, estimation, control, and artificial intelligence. This research was applied to the control of a subsonic transport aircraft in the airport terminal area.

Empirical Estimates of 0Day Vulnerabilities in Control Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miles A. McQueen; Wayne F. Boyer; Sean M. McBride

2009-01-01

We define a 0Day vulnerability to be any vulnerability, in deployed software, which has been discovered by at least one person but has not yet been publicly announced or patched. These 0Day vulnerabilities are of particular interest when assessing the risk to well managed control systems which have already effectively mitigated the publicly known vulnerabilities. In these well managed systems the risk contribution from 0Days will have proportionally increased. To aid understanding of how great a risk 0Days may pose to control systems, an estimate of how many are in existence is needed. Consequently, using the 0Day definition given above,more » we developed and applied a method for estimating how many 0Day vulnerabilities are in existence on any given day. The estimate is made by: empirically characterizing the distribution of the lifespans, measured in days, of 0Day vulnerabilities; determining the number of vulnerabilities publicly announced each day; and applying a novel method for estimating the number of 0Day vulnerabilities in existence on any given day using the number of vulnerabilities publicly announced each day and the previously derived distribution of 0Day lifespans. The method was first applied to a general set of software applications by analyzing the 0Day lifespans of 491 software vulnerabilities and using the daily rate of vulnerability announcements in the National Vulnerability Database. This led to a conservative estimate that in the worst year there were, on average, 2500 0Day software related vulnerabilities in existence on any given day. Using a smaller but intriguing set of 15 0Day software vulnerability lifespans representing the actual time from discovery to public disclosure, we then made a more aggressive estimate. In this case, we estimated that in the worst year there were, on average, 4500 0Day software vulnerabilities in existence on any given day. We then proceeded to identify the subset of software applications likely to be used in some control systems, analyzed the associated subset of vulnerabilities, and characterized their lifespans. Using the previously developed method of analysis, we very conservatively estimated 250 control system related 0Day vulnerabilities in existence on any given day. While reasonable, this first order estimate for control systems is probably far more conservative than those made for general software systems since the estimate did not include vulnerabilities unique to control system specific components. These control system specific vulnerabilities were unable to be included in the estimate for a variety of reasons with the most problematic being that the public announcement of unique control system vulnerabilities is very sparse. Consequently, with the intent to improve the above 0Day estimate for control systems, we first identified the additional, unique to control systems, vulnerability estimation constraints and then investigated new mechanisms which may be useful for estimating the number of unique 0Day software vulnerabilities found in control system components. We proceeded to identify a number of new mechanisms and approaches for estimating and incorporating control system specific vulnerabilities into an improved 0Day estimation method. These new mechanisms and approaches appear promising and will be more rigorously evaluated during the course of the next year.« less

Software reliability models for critical applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pham, H.; Pham, M.

This report presents the results of the first phase of the ongoing EG G Idaho, Inc. Software Reliability Research Program. The program is studying the existing software reliability models and proposes a state-of-the-art software reliability model that is relevant to the nuclear reactor control environment. This report consists of three parts: (1) summaries of the literature review of existing software reliability and fault tolerant software reliability models and their related issues, (2) proposed technique for software reliability enhancement, and (3) general discussion and future research. The development of this proposed state-of-the-art software reliability model will be performed in the secondmore » place. 407 refs., 4 figs., 2 tabs.« less

Software reliability models for critical applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pham, H.; Pham, M.

This report presents the results of the first phase of the ongoing EG&G Idaho, Inc. Software Reliability Research Program. The program is studying the existing software reliability models and proposes a state-of-the-art software reliability model that is relevant to the nuclear reactor control environment. This report consists of three parts: (1) summaries of the literature review of existing software reliability and fault tolerant software reliability models and their related issues, (2) proposed technique for software reliability enhancement, and (3) general discussion and future research. The development of this proposed state-of-the-art software reliability model will be performed in the second place.more » 407 refs., 4 figs., 2 tabs.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Laros III, James H.; DeBonis, David; Grant, Ryan

Measuring and controlling the power and energy consumption of high performance computing systems by various components in the software stack is an active research area [13, 3, 5, 10, 4, 21, 19, 16, 7, 17, 20, 18, 11, 1, 6, 14, 12]. Implementations in lower level software layers are beginning to emerge in some production systems, which is very welcome. To be most effective, a portable interface to measurement and control features would significantly facilitate participation by all levels of the software stack. We present a proposal for a standard power Application Programming Interface (API) that endeavors to cover themore » entire software space, from generic hardware interfaces to the input from the computer facility manager.« less

Measuring software development characteristics in the local environment. [considering project requirements for spacecraft control

NASA Technical Reports Server (NTRS)

Basili, V. R.; Zelkowitz, M. V.

1978-01-01

In a brief evaluation of software-related considerations, it is found that suitable approaches for software development depend to a large degree on the characteristics of the particular project involved. An analysis is conducted of development problems in an environment in which ground support software is produced for spacecraft control. The amount of work involved is in the range from 6 to 10 man-years. Attention is given to a general project summary, a programmer/analyst survey, a component summary, a component status report, a resource summary, a change report, a computer program run analysis, aspects of data collection on a smaller scale, progress forecasting, problems of overhead, and error analysis.

ARC-2007-ACD07-0140-001

NASA Image and Video Library

2007-07-31

David L. Iverson of NASA Ames Research center, Moffett Field, California, led development of computer software to monitor the conditions of the gyroscopes that keep the International Space Station (ISS) properly oriented in space as the ISS orbits Earth. The gyroscopes are flywheels that control the station's attitude without the use of propellant fuel. NASA computer scientists designed the new software, the Inductive Monitoring System, to detect warning signs that precede a gyroscope's failure. According to NASA officials, engineers will add the new software tool to a group of existing tools to identify and track problems related to the gyroscopes. If the software detects warning signs, it will quickly warn the space station's mission control center.

LMJ Points Plus v2.6

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kertesz, Vilmos

Short summary of the software's functionality: • built-in scan feature to acquire optical image of the surface to be analyzed • click-and-point selection of points of interest on the surface • supporting standalone autosampler/HPLC/MS operation: creating independent batch files after points of interests are selected for LEAPShell (autosampler control software from Leap Technologies) and Analyst® (mass spectrometry (MS) software from AB Sciex) • supporting integrated autosampler/HPLC/MS operation: creating one batch file for all instruments controlled by Analyst® (mass spectrometry software from AB Sciex) after points of interests are selected •creating heatmaps of analytes of interests from collected MS files inmore » a hand-off fashion« less

Intelligent fault management for the Space Station active thermal control system

NASA Technical Reports Server (NTRS)

Hill, Tim; Faltisco, Robert M.

1992-01-01

The Thermal Advanced Automation Project (TAAP) approach and architecture is described for automating the Space Station Freedom (SSF) Active Thermal Control System (ATCS). The baseline functionally and advanced automation techniques for Fault Detection, Isolation, and Recovery (FDIR) will be compared and contrasted. Advanced automation techniques such as rule-based systems and model-based reasoning should be utilized to efficiently control, monitor, and diagnose this extremely complex physical system. TAAP is developing advanced FDIR software for use on the SSF thermal control system. The goal of TAAP is to join Knowledge-Based System (KBS) technology, using a combination of rules and model-based reasoning, with conventional monitoring and control software in order to maximize autonomy of the ATCS. TAAP's predecessor was NASA's Thermal Expert System (TEXSYS) project which was the first large real-time expert system to use both extensive rules and model-based reasoning to control and perform FDIR on a large, complex physical system. TEXSYS showed that a method is needed for safely and inexpensively testing all possible faults of the ATCS, particularly those potentially damaging to the hardware, in order to develop a fully capable FDIR system. TAAP therefore includes the development of a high-fidelity simulation of the thermal control system. The simulation provides realistic, dynamic ATCS behavior and fault insertion capability for software testing without hardware related risks or expense. In addition, thermal engineers will gain greater confidence in the KBS FDIR software than was possible prior to this kind of simulation testing. The TAAP KBS will initially be a ground-based extension of the baseline ATCS monitoring and control software and could be migrated on-board as additional computation resources are made available.

15 CFR 774.2 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-01-01

...” that “incorporate” commodities or software on the Commerce Control List (Supplement No. 1 to part 774... the practice of medicine (does not include medical research). (2) Commodities or software are considered “incorporated” if the commodity or software is: Essential to the functioning of the medical...

48 CFR 252.251-7000 - Ordering from Government supply sources.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Enterprise Software Agreements, the Contractor shall follow the terms of the applicable schedule or agreement... Enterprise Software Agreement contractor). (2) The following statement: Any price reductions negotiated as part of an Enterprise Software Agreement issued under a Federal Supply Schedule contract shall control...

Guideline for Software Documentation Management.

ERIC Educational Resources Information Center

National Bureau of Standards (DOC), Washington, DC.

Designed as a basic reference for federal personnel concerned with the development, maintenance, enhancement, control, and management of computer-based systems, this manual provides a general overview of the software development process and software documentation issues so that managers can assess their own documentation requirements. Reference is…

Constructing a working taxonomy of functional Ada software components for real-time embedded system applications

NASA Technical Reports Server (NTRS)

Wallace, Robert

1986-01-01

A major impediment to a systematic attack on Ada software reusability is the lack of an effective taxonomy for software component functions. The scope of all possible applications of Ada software is considered too great to allow the practical development of a working taxonomy. Instead, for the purposes herein, the scope of Ada software application is limited to device and subsystem control in real-time embedded systems. A functional approach is taken in constructing the taxonomy tree for identified Ada domain. The use of modular software functions as a starting point fits well with the object oriented programming philosophy of Ada. Examples of the types of functions represented within the working taxonomy are real time kernels, interrupt service routines, synchronization and message passing, data conversion, digital filtering and signal conditioning, and device control. The constructed taxonomy is proposed as a framework from which a need analysis can be performed to reveal voids in current Ada real-time embedded programming efforts for Space Station.

Three-phase Four-leg Inverter LabVIEW FPGA Control Code

DOE Office of Scientific and Technical Information (OSTI.GOV)

In the area of power electronics control, Field Programmable Gate Arrays (FPGAs) have the capability to outperform their Digital Signal Processor (DSP) counterparts due to the FPGA’s ability to implement true parallel processing and therefore facilitate higher switching frequencies, higher control bandwidth, and/or enhanced functionality. National Instruments (NI) has developed two platforms, Compact RIO (cRIO) and Single Board RIO (sbRIO), which combine a real-time processor with an FPGA. The FPGA can be programmed with a subset of the well-known LabVIEW graphical programming language. The use of cRIO and sbRIO for power electronics control has developed over the last few yearsmore » to include control of three-phase inverters. Most three-phase inverter topologies include three switching legs. The addition of a fourth-leg to natively generate the neutral connection allows the inverter to serve single-phase loads in a microgrid or stand-alone power system and to balance the three-phase voltages in the presence of significant load imbalance. However, the control of a four-leg inverter is much more complex. In particular, instead of standard two-dimensional space vector modulation (SVM), the inverter requires three-dimensional space vector modulation (3D-SVM). The candidate software implements complete control algorithms in LabVIEW FPGA for a three-phase four-leg inverter. The software includes feedback control loops, three-dimensional space vector modulation gate-drive algorithms, advanced alarm handling capabilities, contactor control, power measurements, and debugging and tuning tools. The feedback control loops allow inverter operation in AC voltage control, AC current control, or DC bus voltage control modes based on external mode selection by a user or supervisory controller. The software includes the ability to synchronize its AC output to the grid or other voltage-source before connection. The software also includes provisions to allow inverter operation in parallel with other voltage regulating devices on the AC or DC buses. This flexibility allows the Inverter to operate as a stand-alone voltage source, connected to the grid, or in parallel with other controllable voltage sources as part of a microgrid or remote power system. In addition, as the inverter is expected to operate under severe unbalanced conditions, the software includes algorithms to accurately compute real and reactive power for each phase based on definitions provided in the IEEE Standard 1459: IEEE Standard Definitions for the Measurement of Electric Power Quantities Under Sinusoidal, Nonsinusoidal, Balanced, or Unbalanced Conditions. Finally, the software includes code to output analog signals for debugging and for tuning of control loops. The software fits on the Xilinx Virtex V LX110 FPGA embedded in the NI cRIO-9118 FPGA chassis, and with a 40 MHz base clock, supports a modulation update rate of 40 MHz, user-settable switching frequencies and synchronized control loop update rates of tens of kHz, and reference waveform generation, including Phase Lock Loop (PLL), update rate of 100 kHz.« less

Designing the Undesignable: Social Software and Control

ERIC Educational Resources Information Center

Dron, Jon

2007-01-01

Social software, such as blogs, wikis, tagging systems and collaborative filters, treats the group as a first-class object within the system. Drawing from theories of transactional distance and control, this paper proposes a model of e-learning that extends traditional concepts of learner-teacher-content interactions to include these emergent…

Advanced technologies for Mission Control Centers

NASA Technical Reports Server (NTRS)

Dalton, John T.; Hughes, Peter M.

1991-01-01

Advance technologies for Mission Control Centers are presented in the form of the viewgraphs. The following subject areas are covered: technology needs; current technology efforts at GSFC (human-machine interface development, object oriented software development, expert systems, knowledge-based software engineering environments, and high performance VLSI telemetry systems); and test beds.

Environmental Control System Software & Hardware Development

NASA Technical Reports Server (NTRS)

Vargas, Daniel Eduardo

2017-01-01

ECS hardware: (1) Provides controlled purge to SLS Rocket and Orion spacecraft. (2) Provide mission-focused engineering products and services. ECS software: (1) NASA requires Compact Unique Identifiers (CUIs); fixed-length identifier used to identify information items. (2) CUI structure; composed of nine semantic fields that aid the user in recognizing its purpose.

An eye on reactor and computer control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schryver, J.; Knee, B.

1992-01-01

At ORNL computer software has been developed to make possible an improved eye-gaze measurement technology. Such an inovation could be the basis for advanced eye-gaze systems that may have applications in reactor control, software development, cognitive engineering, evaluation of displays, prediction of mental workloads, and military target recognition.

40 CFR 721.30 - EPA approval of alternative control measures.

Code of Federal Regulations, 2013 CFR

2013-07-01

...), must submit the request to EPA via EPA's Central Data Exchange (CDX) using EPA-provided e-PMN software... obtain e-PMN software. Support documents related to these requests must be submitted in the manner set... involved. (5) The specifications of the alternative worker exposure control measures or environmental...

40 CFR 721.30 - EPA approval of alternative control measures.

Code of Federal Regulations, 2011 CFR

2011-07-01

...), must submit the request to EPA via EPA's Central Data Exchange (CDX) using EPA-provided e-PMN software... obtain e-PMN software. Support documents related to these requests must be submitted in the manner set... involved. (5) The specifications of the alternative worker exposure control measures or environmental...

40 CFR 721.30 - EPA approval of alternative control measures.

Code of Federal Regulations, 2012 CFR

2012-07-01

...), must submit the request to EPA via EPA's Central Data Exchange (CDX) using EPA-provided e-PMN software... obtain e-PMN software. Support documents related to these requests must be submitted in the manner set... involved. (5) The specifications of the alternative worker exposure control measures or environmental...

Product Definition Data Interface (PDDI) Product Specification

DTIC Science & Technology

1991-07-01

syntax of the language gives a precise specification of the data without interpretation of it. M - Constituent Read Block. CSECT - Control Section, the...to conform to the PDDI Access Software’s internal data representation so that it may be further processed. JCL - Job Control Language - IBM language...software development and life cycle * phases. OUALITY CONTROL - The planned and systematic application of all actions (management/technical) necessary to

Flight Controller Software Protects Lightweight Flexible Aircraft

NASA Technical Reports Server (NTRS)

2015-01-01

Lightweight flexible aircraft may be the future of aviation, but a major problem is their susceptibility to flutter-uncontrollable vibrations that can destroy wings. Armstrong Flight Research Center awarded SBIR funding to Minneapolis, Minnesota-based MUSYN Inc. to develop software that helps program flight controllers to suppress flutter. The technology is now available for aircraft manufacturers and other industries that use equipment with automated controls.

HERMES travels by CAN bus

NASA Astrophysics Data System (ADS)

Waller, Lewis G.; Shortridge, Keith; Farrell, Tony J.; Vuong, Minh; Muller, Rolf; Sheinis, Andrew I.

2014-07-01

The new HERMES spectrograph represents the first foray by AAO into the use of commercial off-the-shelf industrial field bus technology for instrument control, and we regard the final system, with its relatively simple wiring requirements, as a great success. However, both software and hardware teams had to work together to solve a number of problems integrating the chosen CANopen/CAN bus system into our normal observing systems. A Linux system running in an industrial PC chassis ran the HERMES control software, using a PCI CAN bus interface connected to a number of distributed CANopen/CAN bus I/O devices and servo amplifiers. In the main, the servo amplifiers performed impressively, although some experimentation with homing algorithms was required, and we hit a significant hurdle when we discovered that we needed to disable some of the encoders used during observations; we learned a lot about how servo amplifiers respond when their encoders are turned off, and about how encoders react to losing power. The software was based around a commercial CANopen library from Copley Controls. Early worries about how this heavily multithreaded library would work with our standard data acquisition system led to the development of a very low-level CANopen software simulator to verify the design. This also enabled the software group to develop and test almost all the control software well in advance of the construction of the hardware. In the end, the instrument went from initial installation at the telescope to successful commissioning remarkably smoothly.

Autonomous power system brassboard

NASA Technical Reports Server (NTRS)

Merolla, Anthony

1992-01-01

The Autonomous Power System (APS) brassboard is a 20 kHz power distribution system which has been developed at NASA Lewis Research Center, Cleveland, Ohio. The brassboard exists to provide a realistic hardware platform capable of testing artificially intelligent (AI) software. The brassboard's power circuit topology is based upon a Power Distribution Control Unit (PDCU), which is a subset of an advanced development 20 kHz electrical power system (EPS) testbed, originally designed for Space Station Freedom (SSF). The APS program is designed to demonstrate the application of intelligent software as a fault detection, isolation, and recovery methodology for space power systems. This report discusses both the hardware and software elements used to construct the present configuration of the brassboard. The brassboard power components are described. These include the solid-state switches (herein referred to as switchgear), transformers, sources, and loads. Closely linked to this power portion of the brassboard is the first level of embedded control. Hardware used to implement this control and its associated software is discussed. An Ada software program, developed by Lewis Research Center's Space Station Freedom Directorate for their 20 kHz testbed, is used to control the brassboard's switchgear, as well as monitor key brassboard parameters through sensors located within these switches. The Ada code is downloaded from a PC/AT, and is resident within the 8086 microprocessor-based embedded controllers. The PC/AT is also used for smart terminal emulation, capable of controlling the switchgear as well as displaying data from them. Intelligent control is provided through use of a T1 Explorer and the Autonomous Power Expert (APEX) LISP software. Real-time load scheduling is implemented through use of a 'C' program-based scheduling engine. The methods of communication between these computers and the brassboard are explored. In order to evaluate the features of both the brassboard hardware and intelligent controlling software, fault circuits have been developed and integrated as part of the brassboard. A description of these fault circuits and their function is included. The brassboard has become an extremely useful test facility, promoting artificial intelligence (AI) applications for power distribution systems. However, there are elements of the brassboard which could be enhanced, thus improving system performance. Modifications and enhancements to improve the brassboard's operation are discussed.

Secure Video Surveillance System Acquisition Software

DOE Office of Scientific and Technical Information (OSTI.GOV)

2009-12-04

The SVSS Acquisition Software collects and displays video images from two cameras through a VPN, and store the images onto a collection controller. The software is configured to allow a user to enter a time window to display up to 2 1/2, hours of video review. The software collects images from the cameras at a rate of 1 image per second and automatically deletes images older than 3 hours. The software code operates in a linux environment and can be run in a virtual machine on Windows XP. The Sandia software integrates the different COTS software together to build themore » video review system.« less

Development of an Information Model for Kidney Transplant Wait List.

PubMed

Bircan, Hüseyin Yüce; Özçelik, Ümit; Uysal, Nida; Demirağ, Alp; Haberal, Mehmet

2015-11-01

Deceased-donor kidney transplant is unique among surgical procedures that are an urgent procedure performed in an elective population. It has not been possible to accurately determine when a given patient will be called for transplant. Patients on the active transplant list can be called for a transplant at any time. As a result, every effort must be made to optimize their health according to best practices and published clinical practice guidelines. Once the patient is placed on the transplant wait list after undergoing an initial extensive evaluation, continued surveillance is required. Therefore, we developed a kidney transplant wait list surveillance software program that alerts organ transplant coordinator on time regarding which patients need a work-up. The new designed software has a database of our waiting patients with their completed and pending controls. The software also has built-in functions to warn the responsible staff with an E-mail. If one of the controls of a recipient delayed, the software sends an automated E-mail to the staff regarding the patients delayed controls. The software is a Web application that works on any platform with a Web browser and Internet connection and allows access by multiple users. The software has been developed with NET platform. The database is SQL server. The software has the following functions: patient communication info, search, alert list, alert E-mail, control entry, and system management. As of January 2014, a total of 21 000 patients were registered on the National Kidney Transplant wait list in Turkey and the kidney transplant wait list had been expanding by 2000 to 3000 patients each year. Therefore computerized wait list programs are crucial to help to transplant centers to keep their patients up-to-date on time.

A Cloud-based, Open-Source, Command-and-Control Software Paradigm for Space Situational Awareness (SSA)

NASA Astrophysics Data System (ADS)

Melton, R.; Thomas, J.

With the rapid growth in the number of space actors, there has been a marked increase in the complexity and diversity of software systems utilized to support SSA target tracking, indication, warning, and collision avoidance. Historically, most SSA software has been constructed with "closed" proprietary code, which limits interoperability, inhibits the code transparency that some SSA customers need to develop domain expertise, and prevents the rapid injection of innovative concepts into these systems. Open-source aerospace software, a rapidly emerging, alternative trend in code development, is based on open collaboration, which has the potential to bring greater transparency, interoperability, flexibility, and reduced development costs. Open-source software is easily adaptable, geared to rapidly changing mission needs, and can generally be delivered at lower costs to meet mission requirements. This paper outlines Ball's COSMOS C2 system, a fully open-source, web-enabled, command-and-control software architecture which provides several unique capabilities to move the current legacy SSA software paradigm to an open source model that effectively enables pre- and post-launch asset command and control. Among the unique characteristics of COSMOS is the ease with which it can integrate with diverse hardware. This characteristic enables COSMOS to serve as the command-and-control platform for the full life-cycle development of SSA assets, from board test, to box test, to system integration and test, to on-orbit operations. The use of a modern scripting language, Ruby, also permits automated procedures to provide highly complex decision making for the tasking of SSA assets based on both telemetry data and data received from outside sources. Detailed logging enables quick anomaly detection and resolution. Integrated real-time and offline data graphing renders the visualization of the both ground and on-orbit assets simple and straightforward.

A Mechanized Decision Support System for Academic Scheduling.

DTIC Science & Technology

1986-03-01

an operational system called software. The first step in the development phase is Design . Designers destribute software control by factoring the Data...SUBJECT TERMS (Continue on reverse if necessary and identify by block number) ELD GROUP SUB-GROUP Scheduling, Decision Support System , Software Design ...scheduling system . It will also examine software - design techniques to identify the most appropriate method- ology for this problem. " - Chapter 3 will

Adaptive Integration of Nonsmooth Dynamical Systems

DTIC Science & Technology

2017-10-11

controlled time stepping method to interactively design running robots. [1] John Shepherd, Samuel Zapolsky, and Evan M. Drumwright, “Fast multi-body...software like this to test software running on my robots. Started working in simulation after attempting to use software like this to test software... running on my robots. The libraries that produce these beautiful results have failed at simulating robotic manipulation. Postulate: It is easier to

Space shuttle orbiter guidance, naviagation and control software functional requirements: Horizontal flight operations

NASA Technical Reports Server (NTRS)

1972-01-01

The shuttle GN&C software functions for horizontal flight operations are defined. Software functional requirements are grouped into two categories: first horizontal flight requirements and full mission horizontal flight requirements. The document privides the intial step in the shuttle GN&C software design process. It also serves as a management tool to identify analyses which are required to define requirements.

Software Reporting Metrics. Revision 2.

DTIC Science & Technology

1985-11-01

MITRE Corporation and ESD. Some of the data has been obtained from Dr. Barry Boehm’s Software Engineering Economics (Ref. 1). Thanks are also given to...data level control management " SP = structured programming Barry W. Boehm, Software Engineering Economics, &©1981, p. 122. Reprinted by permission of...investigated and implemented in future prototypes. 43 REFERENCES For further reading: " 1. Boehm, Barry W. Software Engineering Economics; Englewood

Control software and electronics architecture design in the framework of the E-ELT instrumentation

NASA Astrophysics Data System (ADS)

Di Marcantonio, P.; Coretti, I.; Cirami, R.; Comari, M.; Santin, P.; Pucillo, M.

2010-07-01

During the last years the European Southern Observatory (ESO), in collaboration with other European astronomical institutes, has started several feasibility studies for the E-ELT (European-Extremely Large Telescope) instrumentation and post-focal adaptive optics. The goal is to create a flexible suite of instruments to deal with the wide variety of scientific questions astronomers would like to see solved in the coming decades. In this framework INAF-Astronomical Observatory of Trieste (INAF-AOTs) is currently responsible of carrying out the analysis and the preliminary study of the architecture of the electronics and control software of three instruments: CODEX (control software and electronics) and OPTIMOS-EVE/OPTIMOS-DIORAMAS (control software). To cope with the increased complexity and new requirements for stability, precision, real-time latency and communications among sub-systems imposed by these instruments, new solutions have been investigated by our group. In this paper we present the proposed software and electronics architecture based on a distributed common framework centered on the Component/Container model that uses OPC Unified Architecture as a standard layer to communicate with COTS components of three different vendors. We describe three working prototypes that have been set-up in our laboratory and discuss their performances, integration complexity and ease of deployment.

Tcl as a Software Environment for a TCS

NASA Astrophysics Data System (ADS)

Terrett, David L.

2002-12-01

This paper describes how the Tcl scripting language and C API has been used as the software environment for a telescope pointing kernel so that new pointing algorithms and software architectures can be developed and tested without needing a real-time operating system or real-time software environment. It has enabled development to continue outside the framework of a specific telescope project while continuing to build a system that is sufficiently complete to be capable of controlling real hardware but expending minimum effort on replacing the services that would normally by provided by a real-time software environment. Tcl is used as a scripting language for configuring the system at startup and then as the command interface for controlling the running system; the Tcl C language API is used to provided a system independent interface to file and socket I/O and other operating system services. The pointing algorithms themselves are implemented as a set of C++ objects calling C library functions that implement the algorithms described in [2]. Although originally designed as a test and development environment, the system, running as a soft real-time process on Linux, has been used to test the SOAR mount control system and will be used as the pointing kernel of the SOAR telescope control system

Real-time software failure characterization

NASA Technical Reports Server (NTRS)

Dunham, Janet R.; Finelli, George B.

1990-01-01

A series of studies aimed at characterizing the fundamentals of the software failure process has been undertaken as part of a NASA project on the modeling of a real-time aerospace vehicle software reliability. An overview of these studies is provided, and the current study, an investigation of the reliability of aerospace vehicle guidance and control software, is examined. The study approach provides for the collection of life-cycle process data, and for the retention and evaluation of interim software life-cycle products.

Dose-Dependent Thresholds of 10-ns Electric Pulse Induced Plasma Membrane Disruption and Cytotoxicity in Multiple Cell Lines

DTIC Science & Technology

2011-01-01

normalized to parallel controls. Flow Cytometry and Confocal Microscopy Upon exposure to 10-ns EP, aliquots of the cellular suspension were added to a tube...Survival data was processed and plotted using GrapherH software (Golden Software, Golden, Colorado). Flow cytometry results were processed in C6 software...Accuri Cytometers, Inc., Ann Arbor, MI) and FCSExpress software (DeNovo Software, Los Angeles, CA). Final analysis and presentation of flow cytometry

Microprocessor based implementation of attitude and shape control of large space structures

NASA Technical Reports Server (NTRS)

Reddy, A. S. S. R.

1984-01-01

The feasibility of off the shelf eight bit and 16 bit microprocessors to implement linear state variable feedback control laws and assessing the real time response to spacecraft dynamics is studied. The complexity of the dynamic model is described along with the appropriate software. An experimental setup of a beam, microprocessor system for implementing the control laws and the needed generalized software to implement any state variable feedback control system is included.

Software-in-the-loop simulation of a quadcopter portion for hybrid aircraft control

NASA Astrophysics Data System (ADS)

Mansoor, Shoaib; Saedan, Mana

2018-01-01

In this paper, we present the design of the software-in-the-loop simulation framework for a quadcopter that is incorporated in our hybrid aircraft. The hybrid aircraft comprises a quad-copter and a fixed wing with one forward thrust rotor. We need to develop a split control system that utilizes a typical quadcopter controller to control four motors/propellers and a supervisor controller to control a forward thrust rotor. The supervisor controller shall take feedback signals from the quadcopter and will command the fifth rotor for stabilizing the hybrid aircraft and resolves problems like thrust saturation. The simulation simulates the control algorithm and verifies the quadcopter’s behavior using MATLAB and Simulink together. Achieving these results, we come to know how our hybrid controller will be implemented, what results to expect once the forward thrust rotor is attached to the quadcopter. The software-in-the-loop simulation of a quadcopter is one of the most effective methods for verifying overall control performance and safety of the hybrid aircraft before actual hardware implementation and flight test.

Optics derotator servo control system for SONG Telescope

NASA Astrophysics Data System (ADS)

Xu, Jin; Ren, Changzhi; Ye, Yu

2012-09-01

The Stellar Oscillations Network Group (SONG) is an initiative which aims at designing and building a groundbased network of 1m telescopes dedicated to the study of phenomena occurring in the time domain. Chinese standard node of SONG is an Alt-Az Telescope of F/37 with 1m diameter. Optics derotator control system of SONG telescope adopts the development model of "Industrial Computer + UMAC Motion Controller + Servo Motor".1 Industrial computer is the core processing part of the motion control, motion control card(UMAC) is in charge of the details on the motion control, Servo amplifier accepts the control commands from UMAC, and drives the servo motor. The position feedback information comes from the encoder, to form a closed loop control system. This paper describes in detail hardware design and software design for the optics derotator servo control system. In terms of hardware design, the principle, structure, and control algorithm of servo system based on optics derotator are analyzed and explored. In terms of software design, the paper proposes the architecture of the system software based on Object-Oriented Programming.

A Brief Survey of the Team Software ProcessSM (TSPSM)

DTIC Science & Technology

2011-10-24

spent more than 20 years in industry as a software engineer, system designer, project leader, and development manager working on control systems...InnerWorkings, Inc. Instituto Tecnologico y de Estudios Superiores de Monterrey Siemens AG SILAC Ingenieria de Software S.A. de C.V

14 CFR 1274.942 - Export licenses.

Code of Federal Regulations, 2011 CFR

2011-01-01

... appropriate licenses or other approvals, if required, for exports of hardware, technical data, and software... installation], where the foreign person will have access to export-controlled technical data or software. (c... software) pursuant to the exemption at 22 CFR 125.4(b)(3). The Agreement Officer or designated...

A Course in Real-Time Embedded Software

ERIC Educational Resources Information Center

Archibald, J. K.; Fife, W. S.

2007-01-01

Embedded systems are increasingly pervasive, and the creation of reliable controlling software offers unique challenges. Embedded software must interact directly with hardware, it must respond to events in a time-critical fashion, and it typically employs concurrency to meet response time requirements. This paper describes an innovative course…

15 CFR Supplement No. 2 to Part 730 - Technical Advisory Committees

Code of Federal Regulations, 2012 CFR

2012-01-01

..., materials, or supplies, including technology, software, and other information, that are subject to export... to a clearly defined grouping of articles, materials, or supplies, including technology, software, or..., including technology, software, and other information, that are subject to export controls because of their...

15 CFR Supplement No. 2 to Part 730 - Technical Advisory Committees

Code of Federal Regulations, 2013 CFR

2013-01-01

..., materials, or supplies, including technology, software, and other information, that are subject to export... to a clearly defined grouping of articles, materials, or supplies, including technology, software, or..., including technology, software, and other information, that are subject to export controls because of their...

15 CFR Supplement No. 2 to Part 730 - Technical Advisory Committees

Code of Federal Regulations, 2014 CFR

2014-01-01

..., materials, or supplies, including technology, software, and other information, that are subject to export... to a clearly defined grouping of articles, materials, or supplies, including technology, software, or..., including technology, software, and other information, that are subject to export controls because of their...

SSME digital control design characteristics

NASA Technical Reports Server (NTRS)

Mitchell, W. T.; Searle, R. F.

1985-01-01

To protect against a latent programming error (software fault) existing in an untried branch combination that would render the space shuttle out of control in a critical flight phase, the Backup Flight System (BFS) was chartered to provide a safety alternative. The BFS is designed to operate in critical flight phases (ascent and descent) by monitoring the activities of the space shuttle flight subsystems that are under control of the primary flight software (PFS) (e.g., navigation, crew interface, propulsion), then, upon manual command by the flightcrew, to assume control of the space shuttle and deliver it to a noncritical flight condition (safe orbit or touchdown). The problems associated with the selection of the PFS/BFS system architecture, the internal BFS architecture, the fault tolerant software mechanisms, and the long term BFS utility are discussed.

A Thermal Expert System (TEXSYS) development overview - AI-based control of a Space Station prototype thermal bus

NASA Technical Reports Server (NTRS)

Glass, B. J.; Hack, E. C.

1990-01-01

A knowledge-based control system for real-time control and fault detection, isolation and recovery (FDIR) of a prototype two-phase Space Station Freedom external thermal control system (TCS) is discussed in this paper. The Thermal Expert System (TEXSYS) has been demonstrated in recent tests to be capable of both fault anticipation and detection and real-time control of the thermal bus. Performance requirements were achieved by using a symbolic control approach, layering model-based expert system software on a conventional numerical data acquisition and control system. The model-based capabilities of TEXSYS were shown to be advantageous during software development and testing. One representative example is given from on-line TCS tests of TEXSYS. The integration and testing of TEXSYS with a live TCS testbed provides some insight on the use of formal software design, development and documentation methodologies to qualify knowledge-based systems for on-line or flight applications.

AnClim and ProClimDB software for data quality control and homogenization of time series

NASA Astrophysics Data System (ADS)

Stepanek, Petr

2015-04-01

During the last decade, a software package consisting of AnClim, ProClimDB and LoadData for processing (mainly climatological) data has been created. This software offers a complex solution for processing of climatological time series, starting from loading the data from a central database (e.g. Oracle, software LoadData), through data duality control and homogenization to time series analysis, extreme value evaluations and RCM outputs verification and correction (ProClimDB and AnClim software). The detection of inhomogeneities is carried out on a monthly scale through the application of AnClim, or newly by R functions called from ProClimDB, while quality control, the preparation of reference series and the correction of found breaks is carried out by the ProClimDB software. The software combines many statistical tests, types of reference series and time scales (monthly, seasonal and annual, daily and sub-daily ones). These can be used to create an "ensemble" of solutions, which may be more reliable than any single method. AnClim software is suitable for educational purposes: e.g. for students getting acquainted with methods used in climatology. Built-in graphical tools and comparison of various statistical tests help in better understanding of a given method. ProClimDB is, on the contrary, tool aimed for processing of large climatological datasets. Recently, functions from R may be used within the software making it more efficient in data processing and capable of easy inclusion of new methods (when available under R). An example of usage is easy comparison of methods for correction of inhomogeneities in daily data (HOM of Paul Della-Marta, SPLIDHOM method of Olivier Mestre, DAP - own method, QM of Xiaolan Wang and others). The software is available together with further information on www.climahom.eu . Acknowledgement: this work was partially funded by the project "Building up a multidisciplinary scientific team focused on drought" No. CZ.1.07/2.3.00/20.0248.

Software safety - A user's practical perspective

NASA Technical Reports Server (NTRS)

Dunn, William R.; Corliss, Lloyd D.

1990-01-01

Software safety assurance philosophy and practices at the NASA Ames are discussed. It is shown that, to be safe, software must be error-free. Software developments on two digital flight control systems and two ground facility systems are examined, including the overall system and software organization and function, the software-safety issues, and their resolution. The effectiveness of safety assurance methods is discussed, including conventional life-cycle practices, verification and validation testing, software safety analysis, and formal design methods. It is concluded (1) that a practical software safety technology does not yet exist, (2) that it is unlikely that a set of general-purpose analytical techniques can be developed for proving that software is safe, and (3) that successful software safety-assurance practices will have to take into account the detailed design processes employed and show that the software will execute correctly under all possible conditions.

Research on Control System of Three - phase Brushless DC Motor for Electric Vehicle

NASA Astrophysics Data System (ADS)

Wang, Zhiwei; Jin, Hai; Guo, Jie; Su, Jie; Wang, Miao

2017-12-01

In order to study the three-phase brushless motor control system of electric vehicle, Freescale9S12XS128 chip is used as the control core, and the power MOSFET is used as the inverter device. The software is compiled by Codewarrior software. The speed control link adopts open-loop control, and the control chip collects the external sensor signal voltage Change control PWM signal output control three-phase brushless DC motor speed. The whole system consists of Hall position detection module, current detection module, power drive module and voltage detection module. The basic functions of three-phase brushless DC motor drive control are realized.

TOOTHPASTEV6.11.3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sankel, David J.; Clair, Aaron B. St.; Langsfield, Joshua D.

2006-11-01

Toothpaste is a graphical user interface and Computer Aided Drafting/Manufacturing (CAD/CAM) software package used to plan tool paths for Galil Motion Control hardware. The software is a tool for computer controlled dispensing of materials. The software may be used for solid freeform fabrication of components or the precision printing of inks. Mathematical calculations are used to produce a set of segments and arcs that when coupled together will fill space. The paths of the segments and arcs are then translated into a machine language that controls the motion of motors and translational stages to produce tool paths in three dimensions.more » As motion begins material(s) are dispensed or printed along the three-dimensional pathway.« less

Research a Novel Integrated and Dynamic Multi-object Trade-Off Mechanism in Software Project

NASA Astrophysics Data System (ADS)

Jiang, Weijin; Xu, Yuhui

Aiming at practical requirements of present software project management and control, the paper presented to construct integrated multi-object trade-off model based on software project process management, so as to actualize integrated and dynamic trade-oil of the multi-object system of project. Based on analyzing basic principle of dynamic controlling and integrated multi-object trade-off system process, the paper integrated method of cybernetics and network technology, through monitoring on some critical reference points according to the control objects, emphatically discussed the integrated and dynamic multi- object trade-off model and corresponding rules and mechanism in order to realize integration of process management and trade-off of multi-object system.

Performing Verification and Validation in Reuse-Based Software Engineering

NASA Technical Reports Server (NTRS)

Addy, Edward A.

1999-01-01

The implementation of reuse-based software engineering not only introduces new activities to the software development process, such as domain analysis and domain modeling, it also impacts other aspects of software engineering. Other areas of software engineering that are affected include Configuration Management, Testing, Quality Control, and Verification and Validation (V&V). Activities in each of these areas must be adapted to address the entire domain or product line rather than a specific application system. This paper discusses changes and enhancements to the V&V process, in order to adapt V&V to reuse-based software engineering.

Ship electric propulsion simulator based on networking technology

NASA Astrophysics Data System (ADS)

Zheng, Huayao; Huang, Xuewu; Chen, Jutao; Lu, Binquan

2006-11-01

According the new ship building tense, a novel electric propulsion simulator (EPS) had been developed in Marine Simulation Center of SMU. The architecture, software function and FCS network technology of EPS and integrated power system (IPS) were described. In allusion to the POD propeller in ship, a special physical model was built. The POD power was supplied from the simulative 6.6 kV Medium Voltage Main Switchboard, its control could be realized in local or remote mode. Through LAN, the simulated feature information of EPS will pass to the physical POD model, which would reflect the real thruster working status in different sea conditions. The software includes vessel-propeller math module, thruster control system, distribution and emergency integrated management, double closed loop control system, vessel static water resistance and dynamic software; instructor main control software. The monitor and control system is realized by real time data collection system and CAN bus technology. During the construction, most devices such as monitor panels and intelligent meters, are developed in lab which were based on embedded microcomputer system with CAN interface to link the network. They had also successfully used in practice and would be suitable for the future demands of digitalization ship.

Monitoring and Controlling an Underwater Robotic Arm

NASA Technical Reports Server (NTRS)

Haas, John; Todd, Brian Keith; Woodcock, Larry; Robinson, Fred M.

2009-01-01

The SSRMS Module 1 software is part of a system for monitoring an adaptive, closed-loop control of the motions of a robotic arm in NASA s Neutral Buoyancy Laboratory, where buoyancy in a pool of water is used to simulate the weightlessness of outer space. This software is so named because the robot arm is a replica of the Space Shuttle Remote Manipulator System (SSRMS). This software is distributed, running on remote joint processors (RJPs), each of which is mounted in a hydraulic actuator comprising the joint of the robotic arm and communicating with a poolside processor denoted the Direct Control Rack (DCR). Each RJP executes the feedback joint-motion control algorithm for its joint and communicates with the DCR. The DCR receives joint-angular-velocity commands either locally from an operator or remotely from computers that simulate the flight like SSRMS and perform coordinated motion calculations based on hand-controller inputs. The received commands are checked for validity before they are transmitted to the RJPs. The DCR software generates a display of the statuses of the RJPs for the DCR operator and can shut down the hydraulic pump when excessive joint-angle error or failure of a RJP is detected.

Design of Control Software for a High-Speed Coherent Doppler Lidar System for CO2 Measurement

NASA Technical Reports Server (NTRS)

Vanvalkenburg, Randal L.; Beyon, Jeffrey Y.; Koch, Grady J.; Yu, Jirong; Singh, Upendra N.; Kavaya, Michael J.

2010-01-01

The design of the software for a 2-micron coherent high-speed Doppler lidar system for CO2 measurement at NASA Langley Research Center is discussed in this paper. The specific strategy and design topology to meet the requirements of the system are reviewed. In order to attain the high-speed digitization of the different types of signals to be sampled on multiple channels, a carefully planned design of the control software is imperative. Samples of digitized data from each channel and their roles in data analysis post processing are also presented. Several challenges of extremely-fast, high volume data acquisition are discussed. The software must check the validity of each lidar return as well as other monitoring channel data in real-time. For such high-speed data acquisition systems, the software is a key component that enables the entire scope of CO2 measurement studies using commercially available system components.

An XML-based method for astronomy software designing

NASA Astrophysics Data System (ADS)

Liao, Mingxue; Aili, Yusupu; Zhang, Jin

XML-based method for standardization of software designing is introduced and analyzed and successfully applied to renovating the hardware and software of the digital clock at Urumqi Astronomical Station. Basic strategy for eliciting time information from the new digital clock of FT206 in the antenna control program is introduced. By FT206, the need to compute how many centuries passed since a certain day with sophisticated formulas is eliminated and it is no longer necessary to set right UT time for the computer holding control over antenna because the information about year, month, day are all deduced from Julian day dwelling in FT206, rather than from computer time. With XML-based method and standard for software designing, various existing designing methods are unified, communications and collaborations between developers are facilitated, and thus Internet-based mode of developing software becomes possible. The trend of development of XML-based designing method is predicted.

Real-Time Monitoring of Scada Based Control System for Filling Process

NASA Astrophysics Data System (ADS)

Soe, Aung Kyaw; Myint, Aung Naing; Latt, Maung Maung; Theingi

2008-10-01

This paper is a design of real-time monitoring for filling system using Supervisory Control and Data Acquisition (SCADA). The monitoring of production process is described in real-time using Visual Basic.Net programming under Visual Studio 2005 software without SCADA software. The software integrators are programmed to get the required information for the configuration screens. Simulation of components is expressed on the computer screen using parallel port between computers and filling devices. The programs of real-time simulation for the filling process from the pure drinking water industry are provided.

Trajectory Software With Upper Atmosphere Model

NASA Technical Reports Server (NTRS)

Barrett, Charles

2012-01-01

The Trajectory Software Applications 6.0 for the Dec Alpha platform has an implementation of the Jacchia-Lineberry Upper Atmosphere Density Model used in the Mission Control Center for International Space Station support. Previous trajectory software required an upper atmosphere to support atmosphere drag calculations in the Mission Control Center. The Functional operation will differ depending on the end-use of the module. In general, the calling routine will use function-calling arguments to specify input to the processor. The atmosphere model will then compute and return atmospheric density at the time of interest.

Advanced Transport Operating System (ATOPS) control display unit software description

NASA Technical Reports Server (NTRS)

Slominski, Christopher J.; Parks, Mark A.; Debure, Kelly R.; Heaphy, William J.

1992-01-01

The software created for the Control Display Units (CDUs), used for the Advanced Transport Operating Systems (ATOPS) project, on the Transport Systems Research Vehicle (TSRV) is described. Module descriptions are presented in a standardized format which contains module purpose, calling sequence, a detailed description, and global references. The global reference section includes subroutines, functions, and common variables referenced by a particular module. The CDUs, one for the pilot and one for the copilot, are used for flight management purposes. Operations performed with the CDU affects the aircraft's guidance, navigation, and display software.

Development of a Software Safety Process and a Case Study of Its Use

NASA Technical Reports Server (NTRS)

Knight, J. C.

1996-01-01

Research in the year covered by this reporting period has been primarily directed toward: continued development of mock-ups of computer screens for operator of a digital reactor control system; development of a reactor simulation to permit testing of various elements of the control system; formal specification of user interfaces; fault-tree analysis including software; evaluation of formal verification techniques; and continued development of a software documentation system. Technical results relating to this grant and the remainder of the principal investigator's research program are contained in various reports and papers.

Sequence design and software environment for real-time navigation of a wireless ferromagnetic device using MRI system and single echo 3D tracking.

PubMed

Chanu, A; Aboussouan, E; Tamaz, S; Martel, S

2006-01-01

Software architecture for the navigation of a ferromagnetic untethered device in a 1D and 2D phantom environment is briefly described. Navigation is achieved using the real-time capabilities of a Siemens 1.5 T Avanto MRI system coupled with a dedicated software environment and a specially developed 3D tracking pulse sequence. Real-time control of the magnetic core is executed through the implementation of a simple PID controller. 1D and 2D experimental results are presented.

Integrated software health management for aerospace guidance, navigation, and control systems: A probabilistic reasoning approach

NASA Astrophysics Data System (ADS)

Mbaya, Timmy

Embedded Aerospace Systems have to perform safety and mission critical operations in a real-time environment where timing and functional correctness are extremely important. Guidance, Navigation, and Control (GN&C) systems substantially rely on complex software interfacing with hardware in real-time; any faults in software or hardware, or their interaction could result in fatal consequences. Integrated Software Health Management (ISWHM) provides an approach for detection and diagnosis of software failures while the software is in operation. The ISWHM approach is based on probabilistic modeling of software and hardware sensors using a Bayesian network. To meet memory and timing constraints of real-time embedded execution, the Bayesian network is compiled into an Arithmetic Circuit, which is used for on-line monitoring. This type of system monitoring, using an ISWHM, provides automated reasoning capabilities that compute diagnoses in a timely manner when failures occur. This reasoning capability enables time-critical mitigating decisions and relieves the human agent from the time-consuming and arduous task of foraging through a multitude of isolated---and often contradictory---diagnosis data. For the purpose of demonstrating the relevance of ISWHM, modeling and reasoning is performed on a simple simulated aerospace system running on a real-time operating system emulator, the OSEK/Trampoline platform. Models for a small satellite and an F-16 fighter jet GN&C (Guidance, Navigation, and Control) system have been implemented. Analysis of the ISWHM is then performed by injecting faults and analyzing the ISWHM's diagnoses.

Experimental demonstration of bandwidth on demand (BoD) provisioning based on time scheduling in software-defined multi-domain optical networks

NASA Astrophysics Data System (ADS)

Zhao, Yongli; Li, Yajie; Wang, Xinbo; Chen, Bowen; Zhang, Jie

2016-09-01

A hierarchical software-defined networking (SDN) control architecture is designed for multi-domain optical networks with the Open Daylight (ODL) controller. The OpenFlow-based Control Virtual Network Interface (CVNI) protocol is deployed between the network orchestrator and the domain controllers. Then, a dynamic bandwidth on demand (BoD) provisioning solution is proposed based on time scheduling in software-defined multi-domain optical networks (SD-MDON). Shared Risk Link Groups (SRLG)-disjoint routing schemes are adopted to separate each tenant for reliability. The SD-MDON testbed is built based on the proposed hierarchical control architecture. Then the proposed time scheduling-based BoD (Ts-BoD) solution is experimentally demonstrated on the testbed. The performance of the Ts-BoD solution is evaluated with respect to blocking probability, resource utilization, and lightpath setup latency.

WIFIP: a web-based user interface for automated synchrotron beamlines.

PubMed

Sallaz-Damaz, Yoann; Ferrer, Jean Luc

2017-09-01

The beamline control software, through the associated graphical user interface (GUI), is the user access point to the experiment, interacting with synchrotron beamline components and providing automated routines. FIP, the French beamline for the Investigation of Proteins, is a highly automatized macromolecular crystallography (MX) beamline at the European Synchrotron Radiation Facility. On such a beamline, a significant number of users choose to control their experiment remotely. This is often performed with a limited bandwidth and from a large choice of computers and operating systems. Furthermore, this has to be possible in a rapidly evolving experimental environment, where new developments have to be easily integrated. To face these challenges, a light, platform-independent, control software and associated GUI are required. Here, WIFIP, a web-based user interface developed at FIP, is described. Further than being the present FIP control interface, WIFIP is also a proof of concept for future MX control software.

Hardware for dynamic quantum computing.

PubMed

Ryan, Colm A; Johnson, Blake R; Ristè, Diego; Donovan, Brian; Ohki, Thomas A

2017-10-01

We describe the hardware, gateware, and software developed at Raytheon BBN Technologies for dynamic quantum information processing experiments on superconducting qubits. In dynamic experiments, real-time qubit state information is fed back or fed forward within a fraction of the qubits' coherence time to dynamically change the implemented sequence. The hardware presented here covers both control and readout of superconducting qubits. For readout, we created a custom signal processing gateware and software stack on commercial hardware to convert pulses in a heterodyne receiver into qubit state assignments with minimal latency, alongside data taking capability. For control, we developed custom hardware with gateware and software for pulse sequencing and steering information distribution that is capable of arbitrary control flow in a fraction of superconducting qubit coherence times. Both readout and control platforms make extensive use of field programmable gate arrays to enable tailored qubit control systems in a reconfigurable fabric suitable for iterative development.

Software-defined networking control plane for seamless integration of multiple silicon photonic switches in Datacom networks.

PubMed

Shen, Yiwen; Hattink, Maarten H N; Samadi, Payman; Cheng, Qixiang; Hu, Ziyiz; Gazman, Alexander; Bergman, Keren

2018-04-16

Silicon photonics based switches offer an effective option for the delivery of dynamic bandwidth for future large-scale Datacom systems while maintaining scalable energy efficiency. The integration of a silicon photonics-based optical switching fabric within electronic Datacom architectures requires novel network topologies and arbitration strategies to effectively manage the active elements in the network. We present a scalable software-defined networking control plane to integrate silicon photonic based switches with conventional Ethernet or InfiniBand networks. Our software-defined control plane manages both electronic packet switches and multiple silicon photonic switches for simultaneous packet and circuit switching. We built an experimental Dragonfly network testbed with 16 electronic packet switches and 2 silicon photonic switches to evaluate our control plane. Observed latencies occupied by each step of the switching procedure demonstrate a total of 344 µs control plane latency for data-center and high performance computing platforms.

T-LECS: The Control Software System for MOIRCS

NASA Astrophysics Data System (ADS)

Yoshikawa, T.; Omata, K.; Konishi, M.; Ichikawa, T.; Suzuki, R.; Tokoku, C.; Katsuno, Y.; Nishimura, T.

2006-07-01

MOIRCS (Multi-Object Infrared Camera and Spectrograph) is a new instrument for the Subaru Telescope. We present the system design of the control software system for MOIRCS, named T-LECS (Tohoku University - Layered Electronic Control System). T-LECS is a PC-Linux based network distributed system. Two PCs equipped with the focal plane array system operate two HAWAII2 detectors, respectively, and another PC is used for user interfaces and a database server. Moreover, these PCs control various devices for observations distributed on a TCP/IP network. T-LECS has three interfaces; interfaces to the devices and two user interfaces. One of the user interfaces is to the integrated observation control system (Subaru Observation Software System) for observers, and another one provides the system developers the direct access to the devices of MOIRCS. In order to help the communication between these interfaces, we employ an SQL database system.

Reliability Testing Using the Vehicle Durability Simulator

DTIC Science & Technology

2017-11-20

remote parameter control (RPC) software. The software is specifically designed for the data collection, analysis, and simulation processes outlined in...4516. 3. TOP 02-2-505 Inspection and Preliminary Operation of Vehicles, 4 February 1987. 4. Multi-Shaker Test and Control : Design , Test, and...currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) 20-11-2017 2. REPORT