Exploring the Peer Interaction Effects on Learning Achievement in a Social Learning Platform Based on Social Network Analysis

ERIC Educational Resources Information Center

Lin, Yu-Tzu; Chen, Ming-Puu; Chang, Chia-Hu; Chang, Pu-Chen

2017-01-01

The benefits of social learning have been recognized by existing research. To explore knowledge distribution in social learning and its effects on learning achievement, we developed a social learning platform and explored students' behaviors of peer interactions by the proposed algorithms based on social network analysis. An empirical study was…

Interactive Exploration of Cosmological Dark-Matter Simulation Data.

PubMed

Scherzinger, Aaron; Brix, Tobias; Drees, Dominik; Volker, Andreas; Radkov, Kiril; Santalidis, Niko; Fieguth, Alexander; Hinrichs, Klaus H

2017-01-01

The winning entry of the 2015 IEEE Scientific Visualization Contest, this article describes a visualization tool for cosmological data resulting from dark-matter simulations. The proposed system helps users explore all aspects of the data at once and receive more detailed information about structures of interest at any time. Moreover, novel methods for visualizing and interactively exploring dark-matter halo substructures are proposed.

EINVis: a visualization tool for analyzing and exploring genetic interactions in large-scale association studies.

PubMed

Wu, Yubao; Zhu, Xiaofeng; Chen, Jian; Zhang, Xiang

2013-11-01

Epistasis (gene-gene interaction) detection in large-scale genetic association studies has recently drawn extensive research interests as many complex traits are likely caused by the joint effect of multiple genetic factors. The large number of possible interactions poses both statistical and computational challenges. A variety of approaches have been developed to address the analytical challenges in epistatic interaction detection. These methods usually output the identified genetic interactions and store them in flat file formats. It is highly desirable to develop an effective visualization tool to further investigate the detected interactions and unravel hidden interaction patterns. We have developed EINVis, a novel visualization tool that is specifically designed to analyze and explore genetic interactions. EINVis displays interactions among genetic markers as a network. It utilizes a circular layout (specially, a tree ring view) to simultaneously visualize the hierarchical interactions between single nucleotide polymorphisms (SNPs), genes, and chromosomes, and the network structure formed by these interactions. Using EINVis, the user can distinguish marginal effects from interactions, track interactions involving more than two markers, visualize interactions at different levels, and detect proxy SNPs based on linkage disequilibrium. EINVis is an effective and user-friendly free visualization tool for analyzing and exploring genetic interactions. It is publicly available with detailed documentation and online tutorial on the web at http://filer.case.edu/yxw407/einvis/. © 2013 WILEY PERIODICALS, INC.

Why Some Walk and Others Don't: Exploring Interactions of Perceived Safety and Social Neighborhood Factors with Psychosocial Cognitions

ERIC Educational Resources Information Center

Beenackers, Marielle A.; Kamphuis, Carlijn B. M.; Mackenbach, Johan P.; Burdorf, Alex; van Lenthe, Frank J.

2013-01-01

Although physical activity is often believed to be influenced by both environmental and individual factors, little is known about their interaction. This study explores interactions of perceived safety and social neighborhood factors with psychosocial cognitions for leisure-time walking. Cross-sectional data were obtained from residents (age 25-75…

Chronodes: Interactive Multifocus Exploration of Event Sequences

PubMed Central

POLACK, PETER J.; CHEN, SHANG-TSE; KAHNG, MINSUK; DE BARBARO, KAYA; BASOLE, RAHUL; SHARMIN, MOUSHUMI; CHAU, DUEN HORNG

2018-01-01

The advent of mobile health (mHealth) technologies challenges the capabilities of current visualizations, interactive tools, and algorithms. We present Chronodes, an interactive system that unifies data mining and human-centric visualization techniques to support explorative analysis of longitudinal mHealth data. Chronodes extracts and visualizes frequent event sequences that reveal chronological patterns across multiple participant timelines of mHealth data. It then combines novel interaction and visualization techniques to enable multifocus event sequence analysis, which allows health researchers to interactively define, explore, and compare groups of participant behaviors using event sequence combinations. Through summarizing insights gained from a pilot study with 20 behavioral and biomedical health experts, we discuss Chronodes’s efficacy and potential impact in the mHealth domain. Ultimately, we outline important open challenges in mHealth, and offer recommendations and design guidelines for future research. PMID:29515937

PyramidalExplorer: A New Interactive Tool to Explore Morpho-Functional Relations of Human Pyramidal Neurons.

PubMed

Toharia, Pablo; Robles, Oscar D; Fernaud-Espinosa, Isabel; Makarova, Julia; Galindo, Sergio E; Rodriguez, Angel; Pastor, Luis; Herreras, Oscar; DeFelipe, Javier; Benavides-Piccione, Ruth

2015-01-01

This work presents PyramidalExplorer, a new tool to interactively explore and reveal the detailed organization of the microanatomy of pyramidal neurons with functionally related models. It consists of a set of functionalities that allow possible regional differences in the pyramidal cell architecture to be interactively discovered by combining quantitative morphological information about the structure of the cell with implemented functional models. The key contribution of this tool is the morpho-functional oriented design that allows the user to navigate within the 3D dataset, filter and perform Content-Based Retrieval operations. As a case study, we present a human pyramidal neuron with over 9000 dendritic spines in its apical and basal dendritic trees. Using PyramidalExplorer, we were able to find unexpected differential morphological attributes of dendritic spines in particular compartments of the neuron, revealing new aspects of the morpho-functional organization of the pyramidal neuron.

PyramidalExplorer: A New Interactive Tool to Explore Morpho-Functional Relations of Human Pyramidal Neurons

PubMed Central

Toharia, Pablo; Robles, Oscar D.; Fernaud-Espinosa, Isabel; Makarova, Julia; Galindo, Sergio E.; Rodriguez, Angel; Pastor, Luis; Herreras, Oscar; DeFelipe, Javier; Benavides-Piccione, Ruth

2016-01-01

This work presents PyramidalExplorer, a new tool to interactively explore and reveal the detailed organization of the microanatomy of pyramidal neurons with functionally related models. It consists of a set of functionalities that allow possible regional differences in the pyramidal cell architecture to be interactively discovered by combining quantitative morphological information about the structure of the cell with implemented functional models. The key contribution of this tool is the morpho-functional oriented design that allows the user to navigate within the 3D dataset, filter and perform Content-Based Retrieval operations. As a case study, we present a human pyramidal neuron with over 9000 dendritic spines in its apical and basal dendritic trees. Using PyramidalExplorer, we were able to find unexpected differential morphological attributes of dendritic spines in particular compartments of the neuron, revealing new aspects of the morpho-functional organization of the pyramidal neuron. PMID:26778972

Using PyMOL to Explore the Effects of ph on Noncovalent Interactions between Immunoglobulin G and Protein A: A Guided-Inquiry Biochemistry Activity

ERIC Educational Resources Information Center

Roche Allred, Zahilyn D.; Tai, Heeyoung; Bretz, Stacey Lowery; Page, Richard C.

2017-01-01

Students' understandings of foundational concepts such as noncovalent interactions, pH and pK[subscript a] are crucial for success in undergraduate biochemistry courses. We developed a guided-inquiry activity to aid students in making connections between noncovalent interactions and pH/pK[subscript a]. Students explore these concepts by examining…

The Students Decision Making in Solving Discount Problem

ERIC Educational Resources Information Center

Abdillah; Nusantara, Toto; Subanji; Susanto, Hery; Abadyo

2016-01-01

This research is reviewing students' process of decision making intuitively, analytically, and interactively. The research done by using discount problem which specially created to explore student's intuition, analytically, and interactively. In solving discount problems, researcher exploring student's decision in determining their attitude which…

Towards An Understanding of Mobile Touch Navigation in a Stereoscopic Viewing Environment for 3D Data Exploration.

PubMed

López, David; Oehlberg, Lora; Doger, Candemir; Isenberg, Tobias

2016-05-01

We discuss touch-based navigation of 3D visualizations in a combined monoscopic and stereoscopic viewing environment. We identify a set of interaction modes, and a workflow that helps users transition between these modes to improve their interaction experience. In our discussion we analyze, in particular, the control-display space mapping between the different reference frames of the stereoscopic and monoscopic displays. We show how this mapping supports interactive data exploration, but may also lead to conflicts between the stereoscopic and monoscopic views due to users' movement in space; we resolve these problems through synchronization. To support our discussion, we present results from an exploratory observational evaluation with domain experts in fluid mechanics and structural biology. These experts explored domain-specific datasets using variations of a system that embodies the interaction modes and workflows; we report on their interactions and qualitative feedback on the system and its workflow.

An Interactive Multimedia Software Program for Exploring Electrochemical Cells.

ERIC Educational Resources Information Center

Greenbowe, Thomas J.

1994-01-01

Describes computer-animated sequences and interactive multimedia instructional programs for use in introductory chemistry which allow students to explore electrochemical cells. The workbench section enables students to manipulate the experimental apparatus, chemicals, and instruments in order to design and build an experiment. The interactive…

Paraeducators' Perceptions and Experiences Working with Diverse Families

ERIC Educational Resources Information Center

Sheehey, Patricia H.; Wells, Jenny C.; Ogata, Veronica F.

2018-01-01

This investigation explored the interactions between paraeducators and the culturally and linguistically diverse families of their students with disabilities. Paraeducators (n = 117) attending a statewide professional development event responded to a questionnaire designed to explore their interactions with diverse parents and families. Results…

New generation of exploration tools: interactive modeling software and microcomputers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krajewski, S.A.

1986-08-01

Software packages offering interactive modeling techniques are now available for use on microcomputer hardware systems. These packages are reasonably priced for both company and independent explorationists; they do not require users to have high levels of computer literacy; they are capable of rapidly completing complex ranges of sophisticated geologic and geophysical modeling tasks; and they can produce presentation-quality output for comparison with real-world data. For example, interactive packages are available for mapping, log analysis, seismic modeling, reservoir studies, and financial projects as well as for applying a variety of statistical and geostatistical techniques to analysis of exploration data. More importantly,more » these packages enable explorationists to directly apply their geologic expertise when developing and fine-tuning models for identifying new prospects and for extending producing fields. As a result of these features, microcomputers and interactive modeling software are becoming common tools in many exploration offices. Gravity and magnetics software programs illustrate some of the capabilities of such exploration tools.« less

Distinct hippocampal versus frontoparietal-network contributions to retrieval and memory-guided exploration

PubMed Central

Bridge, Donna J.; Cohen, Neal J.; Voss, Joel L.

2017-01-01

Memory can profoundly influence new learning, presumably because memory optimizes exploration of to-be-learned material. Although hippocampus and frontoparietal networks have been implicated in memory-guided exploration, their specific and interactive roles have not been identified. We examined eye movements during fMRI scanning to identify neural correlates of the influences of memory retrieval on exploration and learning. Following retrieval of one object in a multi-object array, viewing was strategically directed away from the retrieved object toward non-retrieved objects, such that exploration was directed towards to-be-learned content. Retrieved objects later served as optimal reminder cues, indicating that exploration caused memory to become structured around the retrieved content. Hippocampal activity was associated with memory retrieval whereas frontoparietal activity varied with strategic viewing patterns deployed following retrieval, thus providing spatiotemporal dissociation of memory retrieval from memory-guided learning strategies. Time-lagged fMRI connectivity analyses indicated that hippocampal activity predicted frontoparietal activity to a greater extent for a condition in which retrieval guided exploration than for a passive control condition in which exploration was not influenced by retrieval. This demonstrates network-level interaction effects specific to influences of memory on strategic exploration. These findings show how memory guides behavior during learning and demonstrate distinct yet interactive hippocampal-frontoparietal roles in implementing strategic exploration behaviors that determine the fate of evolving memory representations. PMID:28471729

Distinct Hippocampal versus Frontoparietal Network Contributions to Retrieval and Memory-guided Exploration.

PubMed

Bridge, Donna J; Cohen, Neal J; Voss, Joel L

2017-08-01

Memory can profoundly influence new learning, presumably because memory optimizes exploration of to-be-learned material. Although hippocampus and frontoparietal networks have been implicated in memory-guided exploration, their specific and interactive roles have not been identified. We examined eye movements during fMRI scanning to identify neural correlates of the influences of memory retrieval on exploration and learning. After retrieval of one object in a multiobject array, viewing was strategically directed away from the retrieved object toward nonretrieved objects, such that exploration was directed toward to-be-learned content. Retrieved objects later served as optimal reminder cues, indicating that exploration caused memory to become structured around the retrieved content. Hippocampal activity was associated with memory retrieval, whereas frontoparietal activity varied with strategic viewing patterns deployed after retrieval, thus providing spatiotemporal dissociation of memory retrieval from memory-guided learning strategies. Time-lagged fMRI connectivity analyses indicated that hippocampal activity predicted frontoparietal activity to a greater extent for a condition in which retrieval guided exploration occurred than for a passive control condition in which exploration was not influenced by retrieval. This demonstrates network-level interaction effects specific to influences of memory on strategic exploration. These findings show how memory guides behavior during learning and demonstrate distinct yet interactive hippocampal-frontoparietal roles in implementing strategic exploration behaviors that determine the fate of evolving memory representations.

Electrical and Chemical Interactions at Mars Workshop. Part 2: Appendix

NASA Technical Reports Server (NTRS)

1992-01-01

The objectives of the workshop were the following: (1) to identify issues related to electrical and chemical interactions between systems and their local environments at Mars; and (2) to recommend means of addressing those issues, including the dispatch of robotic spacecraft to Mars to acquire necessary information. Presentations about Mars' surface and orbital environments, Space Exploration Initiative (SEI) systems, environmental interactions, modeling and analysis, and plans for exploration are presented in viewgraph form.

Explicit Instructional Interactions: Exploring the Black Box of a Tier 2 Mathematics Intervention

ERIC Educational Resources Information Center

Doabler, Christian T.; Clarke, Ben; Stoolmiller, Mike; Kosty, Derek B.; Fien, Hank; Smolkowski, Keith; Baker, Scott K.

2017-01-01

A critical aspect of intervention research is investigating the active ingredients that underlie intensive interventions and their theories of change. This study explored the rate of instructional interactions within treatment groups to determine whether they offered explanatory power of an empirically validated Tier 2 kindergarten mathematics…

An Exploration of Teachers' Agency and Social Relationships within Dyslexia-Support Provision in an English Secondary School

ERIC Educational Resources Information Center

Ross, Helen

2017-01-01

This article explores teachers' experiences of dyslexia and classroom interventions via lesson observations and semi-structured interviews. These experiences were analysed through a Bourdieusien lens, based on Jenkins's "levels of interaction", to delineate power relationships inherent in classroom interactions, teachers' interactions…

Exploring the roles of interaction and flow in explaining nurses' e-learning acceptance.

PubMed

Cheng, Yung-Ming

2013-01-01

To provide safe and competent patient care, it is very important that medical institutions should provide nurses with continuing education by using appropriate learning methods. As compared to traditional learning, electronic learning (e-learning) is a more flexible method for nurses' in-service learning. Hence, e-learning is expected to play a pivotal role in providing continuing education for nurses. This study's purpose was to explore the role and relevance of interaction factors, intrinsic motivator (i.e., flow), and extrinsic motivators (i.e., perceived usefulness (PU) and perceived ease of use (PEOU)) in explaining nurses' intention to use the e-learning system. Based on the technology acceptance model (TAM) with the flow theory, this study's research model presents three types of interaction factors, learner-system interaction, instructor-learner interaction, and learner-learner interaction to construct an extended TAM to explore nurses' intention to use the e-learning system. Sample data were gathered from nurses at two regional hospitals in Taiwan. A total of 320 questionnaires were distributed, 254 (79.375%) questionnaires were returned. Consequently, 218 usable questionnaires were analyzed in this study, with a usable response rate of 68.125%. First, confirmatory factor analysis was used to develop the measurement model. Second, to explore the causal relationships among all constructs, the structural model for the research model was tested by using structural equation modeling. First, learner-system interaction, instructor-learner interaction, and learner-learner interaction respectively had significant effects on PU, PEOU, and flow. Next, flow had significant effects on PU and PEOU, and PEOU had a significant effect on PU. Finally, the effects of flow, PU, and PEOU on intention to use were significant. Synthetically speaking, learner-system interaction, instructor-learner interaction, and learner-learner interaction can indirectly make significant impacts on nurses' usage intention of the e-learning system via their extrinsic motivators (i.e., PU and PEOU) and intrinsic motivator (i.e., flow). Copyright © 2012 Elsevier Ltd. All rights reserved.

The development of a virtual camera system for astronaut-rover planetary exploration.

PubMed

Platt, Donald W; Boy, Guy A

2012-01-01

A virtual assistant is being developed for use by astronauts as they use rovers to explore the surface of other planets. This interactive database, called the Virtual Camera (VC), is an interactive database that allows the user to have better situational awareness for exploration. It can be used for training, data analysis and augmentation of actual surface exploration. This paper describes the development efforts and Human-Computer Interaction considerations for implementing a first-generation VC on a tablet mobile computer device. Scenarios for use will be presented. Evaluation and success criteria such as efficiency in terms of processing time and precision situational awareness, learnability, usability, and robustness will also be presented. Initial testing and the impact of HCI design considerations of manipulation and improvement in situational awareness using a prototype VC will be discussed.

Quantitative Imaging In Pathology (QUIP) | Informatics Technology for Cancer Research (ITCR)

Cancer.gov

This site hosts web accessible applications, tools and data designed to support analysis, management, and exploration of whole slide tissue images for cancer research. The following tools are included: caMicroscope: A digital pathology data management and visualization plaform that enables interactive viewing of whole slide tissue images and segmentation results. caMicroscope can be also used independently of QUIP. FeatureExplorer: An interactive tool to allow patient-level feature exploration across multiple dimensions.

A Grammar-based Approach for Modeling User Interactions and Generating Suggestions During the Data Exploration Process.

PubMed

Dabek, Filip; Caban, Jesus J

2017-01-01

Despite the recent popularity of visual analytics focusing on big data, little is known about how to support users that use visualization techniques to explore multi-dimensional datasets and accomplish specific tasks. Our lack of models that can assist end-users during the data exploration process has made it challenging to learn from the user's interactive and analytical process. The ability to model how a user interacts with a specific visualization technique and what difficulties they face are paramount in supporting individuals with discovering new patterns within their complex datasets. This paper introduces the notion of visualization systems understanding and modeling user interactions with the intent of guiding a user through a task thereby enhancing visual data exploration. The challenges faced and the necessary future steps to take are discussed; and to provide a working example, a grammar-based model is presented that can learn from user interactions, determine the common patterns among a number of subjects using a K-Reversible algorithm, build a set of rules, and apply those rules in the form of suggestions to new users with the goal of guiding them along their visual analytic process. A formal evaluation study with 300 subjects was performed showing that our grammar-based model is effective at capturing the interactive process followed by users and that further research in this area has the potential to positively impact how users interact with a visualization system.

Interaction Mindsets, Interactional Behaviors, and L2 Development: An Affective-Social-Cognitive Model

ERIC Educational Resources Information Center

Sato, Masatoshi

2017-01-01

This classroom-based study explored links among second language (L2) learners' interaction mindsets, interactional behaviors, and L2 development in the context of peer interaction. While peer interaction research has revealed that certain interactional behaviors (e.g., receiving corrective feedback and engaging in collaborative interaction) assist…

Environmental interactions in Space Exploration: Announcement of the formation of an Environmental Interactions Working Group

NASA Technical Reports Server (NTRS)

Kolecki, Joseph C.; Hillard, G. Barry

1991-01-01

With the advent of the Space Exploration Initiative, the possibility of designing and using systems on scales not heretofore attempted presents exciting new challenges in systems design and space science. The environments addressed by the Space Exploration Initiative include the surfaces of the Moon and Mars, as well as the varied plasma and field environments which will be encountered by humans and cargo enroute to these destinations. Systems designers will need to understand environmental interactions and be able to model these mechanisms from the earliest conceptual design stages through design completion. To the end of understanding environmental interactions and establishing robotic precursor mission requirements, an Environmental Interactions Working Group has been established as part of the Robotic Missions Working Group. The current paper describes the working group and gives an update of its current activities. Working group charter and operation are reviewed, background information on the environmental interactions and their characteristics is offered, and the current status of the group's activities is presented along with anticipations for the future.

Interactive visual exploration and analysis of origin-destination data

NASA Astrophysics Data System (ADS)

Ding, Linfang; Meng, Liqiu; Yang, Jian; Krisp, Jukka M.

2018-05-01

In this paper, we propose a visual analytics approach for the exploration of spatiotemporal interaction patterns of massive origin-destination data. Firstly, we visually query the movement database for data at certain time windows. Secondly, we conduct interactive clustering to allow the users to select input variables/features (e.g., origins, destinations, distance, and duration) and to adjust clustering parameters (e.g. distance threshold). The agglomerative hierarchical clustering method is applied for the multivariate clustering of the origin-destination data. Thirdly, we design a parallel coordinates plot for visualizing the precomputed clusters and for further exploration of interesting clusters. Finally, we propose a gradient line rendering technique to show the spatial and directional distribution of origin-destination clusters on a map view. We implement the visual analytics approach in a web-based interactive environment and apply it to real-world floating car data from Shanghai. The experiment results show the origin/destination hotspots and their spatial interaction patterns. They also demonstrate the effectiveness of our proposed approach.

The Cognitive Neuroscience of the Teacher-Student Interaction

ERIC Educational Resources Information Center

Battro, Antonio M.; Calero, Cecilia I.; Goldin, Andrea P.; Holper, Lisa; Pezzatti, Laura; Shalóm, Diego E.; Sigman, Mariano

2013-01-01

Pedagogy is the science and art of teaching. Each generation needs to explore the history, theory, and practice of the teacher-student interaction. Here we pave the path to develop a science that explores the cognitive and physiological processes involved in the human capacity to communicate knowledge through teaching. We review examples from our…

Exploring Relationships between Students' Interaction and Learning with a Haptic Virtual Biomolecular Model

ERIC Educational Resources Information Center

Schonborn, Konrad J.; Bivall, Petter; Tibell, Lena A. E.

2011-01-01

This study explores tertiary students' interaction with a haptic virtual model representing the specific binding of two biomolecules, a core concept in molecular life science education. Twenty students assigned to a "haptics" (experimental) or "no-haptics" (control) condition performed a "docking" task where users sought the most favourable…

Exploring Educational Interactions: A Lesson for the Development of Interdisciplinary Working?

ERIC Educational Resources Information Center

McGinley, Brian P.; Grieve, Ann M.

2011-01-01

This paper reports a small-scale study exploring the communicative interactions of secondary teachers and community educators with colleagues and learners in educational environments. This research is conducted in a changing educational landscape where there is a more holistic approach to education being adopted and where an extended Scottish…

Patterns of Interaction in Family Relationships and the Development of Identity Exploration in Adolescence.

ERIC Educational Resources Information Center

Grotevant, Harold D.; Cooper, Catherine R.

1985-01-01

Developed a model of individuation in family relationships focused on communicative processes. Expressions of four dimensions of the model (self-esteem, separateness, permeability, and mutuality) were predicted to be positively associated with identity exploration in adolescents. Analysis of observations of families in a Family Interaction Task…

Emotional Demands, Emotional Labour and Occupational Outcomes in School Principals: Modelling the Relationships

ERIC Educational Resources Information Center

Maxwell, Aimee; Riley, Philip

2017-01-01

Most research into emotional labour is focussed on front-line service staff and health professionals, in short-term interactions. Little exists exploring the emotional labour involved in repeated on-going interactions by educational leaders with key stakeholders. This study explored the relationships between emotional demands, three emotional…

Interacting with… What? Exploring Children's Social and Sensory Practices in a Science Discovery Centre

ERIC Educational Resources Information Center

Dicks, Bella

2013-01-01

This paper presents findings from a qualitative UK study exploring the social practices of schoolchildren visiting an interactive science discovery centre. It is promoted as a place for "learning through doing", but the multi-modal, ethnographic methods adopted suggest that children were primarily engaged in (1) sensory pleasure-taking…

Culture, Learning Styles, and Web 2.0

ERIC Educational Resources Information Center

Olaniran, Bolanle A.

2009-01-01

This article explores Web 2.0 in interactive learning environments. Specifically, the article examines Web 2.0 as an interactive learning platform that holds potential, but is also limited by learning styles and cultural value preferences. The article explores the issue of control from both teacher and learner perspectives, and in particular the…

Promoting Interactive Learning: A Classroom Exercise to Explore Foraging Strategies

ERIC Educational Resources Information Center

Beaumont, Ellen S.; Rowe, Graham; Mikhaylov, Natalie S.

2012-01-01

We describe a classroom exercise to allow students to explore foraging strategies in higher vertebrates. The exercise includes an initial interactive session in which students act as predators and are guided through foraging simulations, and a subsequent student-led session where classmates are employed as experimental subjects. Students rated the…

Dynamic and Interactive Mathematics Learning Environments: The Case of Teaching the Limit Concept

ERIC Educational Resources Information Center

Martinovic, Dragana; Karadag, Zekeriya

2012-01-01

This theoretical study is an attempt to explore the potential of the dynamic and interactive mathematics learning environments (DIMLE) in relation to the technological pedagogical content knowledge (TPACK) framework. DIMLE are developed with intent to support learning mathematics through free exploration in a less constrained environment. A…

Cluster structures influenced by interaction with a surface.

PubMed

Witt, Christopher; Dieterich, Johannes M; Hartke, Bernd

2018-05-30

Clusters on surfaces are vitally important for nanotechnological applications. Clearly, cluster-surface interactions heavily influence the preferred cluster structures, compared to clusters in vacuum. Nevertheless, systematic explorations and an in-depth understanding of these interactions and how they determine the cluster structures are still lacking. Here we present an extension of our well-established non-deterministic global optimization package OGOLEM from isolated clusters to clusters on surfaces. Applying this approach to intentionally simple Lennard-Jones test systems, we produce a first systematic exploration that relates changes in cluster-surface interactions to resulting changes in adsorbed cluster structures.

Combining computational analyses and interactive visualization for document exploration and sensemaking in jigsaw.

PubMed

Görg, Carsten; Liu, Zhicheng; Kihm, Jaeyeon; Choo, Jaegul; Park, Haesun; Stasko, John

2013-10-01

Investigators across many disciplines and organizations must sift through large collections of text documents to understand and piece together information. Whether they are fighting crime, curing diseases, deciding what car to buy, or researching a new field, inevitably investigators will encounter text documents. Taking a visual analytics approach, we integrate multiple text analysis algorithms with a suite of interactive visualizations to provide a flexible and powerful environment that allows analysts to explore collections of documents while sensemaking. Our particular focus is on the process of integrating automated analyses with interactive visualizations in a smooth and fluid manner. We illustrate this integration through two example scenarios: an academic researcher examining InfoVis and VAST conference papers and a consumer exploring car reviews while pondering a purchase decision. Finally, we provide lessons learned toward the design and implementation of visual analytics systems for document exploration and understanding.

Exploring synergistic interactions and catalysts in complex interventions: longitudinal, mixed methods case studies of an optimised multi-level suicide prevention intervention in four european countries (Ospi-Europe).

PubMed

Harris, Fiona M; Maxwell, Margaret; O'Connor, Rory; Coyne, James C; Arensman, Ella; Coffey, Claire; Koburger, Nicole; Gusmão, Ricardo; Costa, Susana; Székely, András; Cserhati, Zoltan; McDaid, David; van Audenhove, Chantal; Hegerl, Ulrich

2016-03-15

The Medical Research Council (MRC) Framework for complex interventions highlights the need to explore interactions between components of complex interventions, but this has not yet been fully explored within complex, non-pharmacological interventions. This paper draws on the process evaluation data of a suicide prevention programme implemented in four European countries to illustrate the synergistic interactions between intervention levels in a complex programme, and to present our method for exploring these. A realist evaluation approach informed the process evaluation, which drew on mixed methods, longitudinal case studies. Data collection consisted of 47 semi-structured interviews, 12 focus groups, one workshop, fieldnoted observations of six programme meetings and 20 questionnaires (delivered at six month intervals to each of the four intervention sites). Analysis drew on the framework approach, facilitated by the use of QSR NVivo (v10). Our qualitative approach to exploring synergistic interactions (QuaSIC) also developed a matrix of hypothesised synergies that were explored within one workshop and two waves of data collection. All four implementation countries provided examples of synergistic interactions that added value beyond the sum of individual intervention levels or components in isolation. For instance, the launch ceremony of the public health campaign (a level 3 intervention) in Ireland had an impact on the community-based professional training, increasing uptake and visibility of training for journalists in particular. In turn, this led to increased media reporting of OSPI activities (monitored as part of the public health campaign) and also led to wider dissemination of editorial guidelines for responsible reporting of suicidal acts. Analysis of the total process evaluation dataset also revealed the new phenomenon of the OSPI programme acting as a catalyst for externally generated (and funded) activity that shared the goals of suicide prevention. The QuaSIC approach enabled us to develop and refine our definition of synergistic interactions and add the innovative concept of catalytic effects. This represents a novel approach to the evaluation of complex interventions. By exploring synergies and catalytic interactions related to a complex intervention or programme, we reveal the added value to planned activities and how they might be maximised.

SLIDE - a web-based tool for interactive visualization of large-scale -omics data.

PubMed

Ghosh, Soumita; Datta, Abhik; Tan, Kaisen; Choi, Hyungwon

2018-06-28

Data visualization is often regarded as a post hoc step for verifying statistically significant results in the analysis of high-throughput data sets. This common practice leaves a large amount of raw data behind, from which more information can be extracted. However, existing solutions do not provide capabilities to explore large-scale raw datasets using biologically sensible queries, nor do they allow user interaction based real-time customization of graphics. To address these drawbacks, we have designed an open-source, web-based tool called Systems-Level Interactive Data Exploration, or SLIDE to visualize large-scale -omics data interactively. SLIDE's interface makes it easier for scientists to explore quantitative expression data in multiple resolutions in a single screen. SLIDE is publicly available under BSD license both as an online version as well as a stand-alone version at https://github.com/soumitag/SLIDE. Supplementary Information are available at Bioinformatics online.

Analysis of yield and oil from a series of canola breeding trials. Part II. Exploring variety by environment interaction using factor analysis.

PubMed

Cullis, B R; Smith, A B; Beeck, C P; Cowling, W A

2010-11-01

Exploring and exploiting variety by environment (V × E) interaction is one of the major challenges facing plant breeders. In paper I of this series, we presented an approach to modelling V × E interaction in the analysis of complex multi-environment trials using factor analytic models. In this paper, we develop a range of statistical tools which explore V × E interaction in this context. These tools include graphical displays such as heat-maps of genetic correlation matrices as well as so-called E-scaled uniplots that are a more informative alternative to the classical biplot for large plant breeding multi-environment trials. We also present a new approach to prediction for multi-environment trials that include pedigree information. This approach allows meaningful selection indices to be formed either for potential new varieties or potential parents.

Does Diversity Matter in the Education Process? An Exploration of Student Interactions by Wealth, Religion, Politics, Race, Ethnicity and Immigrant Status at the University of California. A Student Experience in the Research University (SERU) Project Research Paper. Research & Occasional Paper Series: CSHE.5.08

ERIC Educational Resources Information Center

Chatman, Steven

2008-01-01

This exploration into student interactions that improve understanding, student attachment, and demographic characteristics of students attending the University of California in the spring of 2006 finds the University to be a diverse and healthy environment. Interactions among students with demographic differences are frequent and are rarely…

Complex molecular assemblies at hand via interactive simulations.

PubMed

Delalande, Olivier; Férey, Nicolas; Grasseau, Gilles; Baaden, Marc

2009-11-30

Studying complex molecular assemblies interactively is becoming an increasingly appealing approach to molecular modeling. Here we focus on interactive molecular dynamics (IMD) as a textbook example for interactive simulation methods. Such simulations can be useful in exploring and generating hypotheses about the structural and mechanical aspects of biomolecular interactions. For the first time, we carry out low-resolution coarse-grain IMD simulations. Such simplified modeling methods currently appear to be more suitable for interactive experiments and represent a well-balanced compromise between an important gain in computational speed versus a moderate loss in modeling accuracy compared to higher resolution all-atom simulations. This is particularly useful for initial exploration and hypothesis development for rare molecular interaction events. We evaluate which applications are currently feasible using molecular assemblies from 1900 to over 300,000 particles. Three biochemical systems are discussed: the guanylate kinase (GK) enzyme, the outer membrane protease T and the soluble N-ethylmaleimide-sensitive factor attachment protein receptors complex involved in membrane fusion. We induce large conformational changes, carry out interactive docking experiments, probe lipid-protein interactions and are able to sense the mechanical properties of a molecular model. Furthermore, such interactive simulations facilitate exploration of modeling parameters for method improvement. For the purpose of these simulations, we have developed a freely available software library called MDDriver. It uses the IMD protocol from NAMD and facilitates the implementation and application of interactive simulations. With MDDriver it becomes very easy to render any particle-based molecular simulation engine interactive. Here we use its implementation in the Gromacs software as an example. Copyright 2009 Wiley Periodicals, Inc.

The in Silico Insight into Carbon Nanotube and Nucleic Acid Bases Interaction.

PubMed

Karimi, Ali Asghar; Ghalandari, Behafarid; Tabatabaie, Seyed Saleh; Farhadi, Mohammad

2016-05-01

To explore practical applications of carbon nanotubes (CNTs) in biomedical fields the properties of their interaction with biomolecules must be revealed. Recent years, the interaction of CNTs with biomolecules is a subject of research interest for practical applications so that previous research explored that CNTs have complementary structure properties with single strand DNA (ssDNA). Hence, the quantum mechanics (QM) method based on ab initio was used for this purpose. Therefore values of binding energy, charge distribution, electronic energy and other physical properties of interaction were studied for interaction of nucleic acid bases and SCNT. In this study, the interaction between nucleic acid bases and a (4, 4) single-walled carbon nanotube (SCNT) were investigated through calculations within quantum mechanics (QM) method at theoretical level of Hartree-Fock (HF) method using 6-31G basis set. Hence, the physical properties such as electronic energy, total dipole moment, charge distributions and binding energy of nucleic acid bases interaction with SCNT were investigated based on HF method. It has been found that the guanine base adsorption is bound stronger to the outer surface of nanotube in comparison to the other bases, consistent with the recent theoretical studies. In the other words, the results explored that guanine interaction with SCNT has optimum level of electronic energy so that their interaction is stable. Also, the calculations illustrated that SCNT interact to nucleic acid bases by noncovalent interaction because of charge distribution an electrostatic area is created in place of interaction. Consequently, small diameter SCNT interaction with nucleic acid bases is noncovalent. Also, the results revealed that small diameter SCNT interaction especially SCNT (4, 4) with nucleic acid bases can be useful in practical application area of biomedical fields such detection and drug delivery.

Crabby Interactions: Fifth Graders Explore Human Impact on the Blue Crab Population

ERIC Educational Resources Information Center

Jeffery, Tonya D.; McCollough, Cherie A.; Moore, Kim

2016-01-01

This article describes a two-day lesson in which fifth-grade students took on the role of marine biology scientists, using their critical-thinking and problem-solving skills to explore human impact on the blue crab ecosystem. The purpose of "Crabby Interactions" was to help students understand the impact of human activities on the local…

Examining Interactions between Problem Posing and Problem Solving with Prospective Primary Teachers: A Case of Using Fractions

ERIC Educational Resources Information Center

Xie, Jinxia; Masingila, Joanna O.

2017-01-01

Existing studies have quantitatively evidenced the relatedness between problem posing and problem solving, as well as the magnitude of this relationship. However, the nature and features of this relationship need further qualitative exploration. This paper focuses on exploring the interactions, i.e., mutual effects and supports, between problem…

Meeting Active Start Guidelines in the ADC-Boykin Program: Infants

ERIC Educational Resources Information Center

Adalbjornsson, Carola F.; Rudisill, Mary E.; Wall, Sarah J.; Howard, Candice H.

2004-01-01

Contrary to past thinking, at birth, infants are capable of exploring their environment and interacting with other humans. They become aware of and learn about their world by observing, exploring, playing, and interacting with their caregivers. Motor skills play a major role in this process, which is achieved by allowing infants to move around,…

TSEMA: interactive prediction of protein pairings between interacting families

PubMed Central

Izarzugaza, José M. G.; Juan, David; Pons, Carles; Ranea, Juan A. G.; Valencia, Alfonso; Pazos, Florencio

2006-01-01

An entire family of methodologies for predicting protein interactions is based on the observed fact that families of interacting proteins tend to have similar phylogenetic trees due to co-evolution. One application of this concept is the prediction of the mapping between the members of two interacting protein families (which protein within one family interacts with which protein within the other). The idea is that the real mapping would be the one maximizing the similarity between the trees. Since the exhaustive exploration of all possible mappings is not feasible for large families, current approaches use heuristic techniques which do not ensure the best solution to be found. This is why it is important to check the results proposed by heuristic techniques and to manually explore other solutions. Here we present TSEMA, the server for efficient mapping assessment. This system calculates an initial mapping between two families of proteins based on a Monte Carlo approach and allows the user to interactively modify it based on performance figures and/or specific biological knowledge. All the explored mappings are graphically shown over a representation of the phylogenetic trees. The system is freely available at . Standalone versions of the software behind the interface are available upon request from the authors. PMID:16845017

Design and study of geosciences data share platform :platform framework, data interoperability, share approach

NASA Astrophysics Data System (ADS)

Lu, H.; Yi, D.

2010-12-01

The Deep Exploration is one of the important approaches to the Geoscience research. Since 1980s we had started it and achieved a lot of data. Researchers usually integrate both data of space exploration and deep exploration to study geological structures and represent the Earth’s subsurface, and analyze and explain on the base of integrated data. Due to the different exploration approach it results the heterogeneity of data, and therefore the data achievement is always of the import issue to make the researchers confused. The problem of data share and interaction has to be solved during the development of the SinoProbe research project. Through the research of domestic and overseas well-known exploration project and geosciences data platform, the subject explores the solution of data share and interaction. Based on SOA we present the deep exploration data share framework which comprises three level: data level is used for the solution of data store and the integration of the heterogeneous data; medial level provides the data service of geophysics, geochemistry, etc. by the means of Web service, and carry out kinds of application combination by the use of GIS middleware and Eclipse RCP; interaction level provides professional and non-professional customer the access to different accuracy data. The framework adopts GeoSciML data interaction approach. GeoSciML is a geosciences information markup language, as an application of the OpenGIS Consortium’s (OGC) Geography Markup Language (GML). It transfers heterogeneous data into one earth frame and implements inter-operation. We dissertate in this article the solution how to integrate the heterogeneous data and share the data in the project of SinoProbe.

Exploring Teachers' Depressive Symptoms, Interaction Quality, and Children's Social-Emotional Development in Head Start

ERIC Educational Resources Information Center

Roberts, Amy; LoCasale-Crouch, Jennifer; Hamre, Bridget; DeCoster, Jamie

2016-01-01

Research Findings: This study explored the role Head Start teachers' (n = 355) depressive symptoms play in their interactions with children and in children's (n = 2,203) social-emotional development, specifically changes in children's problem behaviors and social skills as reported by parents and teachers during the preschool year. Results of the…

Exploring the Use of MXit: A Cell-Phone Social Network to Facilitate Learning in Distance Education

ERIC Educational Resources Information Center

Makoe, Mpine

2010-01-01

The aim of this paper is to investigate the pedagogical suitability of using cell phones to enhance learning through social interaction in distance education. Social interaction was used as a conceptual framework to explore the potential for using "MXit"--a cell-phone instant messaging system--to support and enhance learning for distance…

Exploring the Role of Physics Representations: An Illustrative Example from Students Sharing Knowledge about Refraction

ERIC Educational Resources Information Center

Fredlund, Tobias; Airey, John; Linder, Cedric

2012-01-01

Research has shown that interactive engagement enhances student learning outcomes. A growing body of research suggests that the representations we use in physics are important in such learning environments. In this paper we draw on a number of sources in the literature to explore the role of representations in interactive engagement in physics. In…

Searching for Pedagogical Adaptations by Exploring Teacher's Tacit Knowledge and Interactional Co-Regulation in the Education of Pupils with Autism

ERIC Educational Resources Information Center

Rama, Irene; Kontu, Elina

2012-01-01

The purpose of this article is to introduce a research design, which aims to find useful pedagogical adaptations for teaching pupils with autism. Autism is a behavioural syndrome characterised by disabilities and dysfunctions in interaction and communication, which is why it is interesting to explore educational processes particularly from an…

Moving Ideas: An Exploration of Students' Use of Dialogue for Writing in History

ERIC Educational Resources Information Center

van Drie, Jannet; van de Ven, Piet-Hein

2017-01-01

In this study, we explored how students make use of whole-class interaction in individual writing. Although various studies show the importance of classroom interaction for writing, little is known about how this works, particularly in history. Starting point is the idea that learning can move from the interpersonal level in classroom discourse to…

Exploring the Contribution of Teaching and Learning Processes in the Construction of Students' Gender Identity in Early Year Classrooms

ERIC Educational Resources Information Center

Baig, Amina

2014-01-01

The present study explores how gender identity construction takes place in a single gender classroom in early years. Qualitative research guided the study design which was conducted in two public sector single gender schools. The data were collected through observations of the teacher-student interaction, student-student interaction, focused group…

Moving First-Year Writing Online: Applying Social Cognitive Theory to an Exploration of Student Study Habits and Interactions

ERIC Educational Resources Information Center

Rendahl, Merry A.

2010-01-01

This dissertation explores study habits and interactions of students in an online first-year writing course. Much research has been conducted about online learning, but little has focused specifically on first-year writing students. First-year writing presents some unique challenges because of the age and preparedness level of traditional…

Interactively Applying the Variational Method to the Dihydrogen Molecule: Exploring Bonding and Antibonding

ERIC Educational Resources Information Center

Cruzeiro, Vinícius Wilian D.; Roitberg, Adrian; Polfer, Nicolas C.

2016-01-01

In this work we are going to present how an interactive platform can be used as a powerful tool to allow students to better explore a foundational problem in quantum chemistry: the application of the variational method to the dihydrogen molecule using simple Gaussian trial functions. The theoretical approach for the hydrogen atom is quite…

Using Tablet Computers in Preschool: How Does the Design of Applications Influence Participation, Interaction and Dialogues?

ERIC Educational Resources Information Center

Palmér, Hanna

2015-01-01

The results in this article explore whether and how the design of applications used on tablet computers influences the interaction and dialogues that occur between children and pedagogues, the participation of children in the activities and the mathematics that can be learned. While mathematics offered a lens to explore the use of tablet devices,…

Organizational Learning from Cross-Cultural Experiences: An Ethnomethodological Case Study Examining the Relative Importance of Social Structure and Cultural Values during Dynamic Interaction

ERIC Educational Resources Information Center

Waldecker, Gary T.

2011-01-01

This study explored how social structure and cultural values dynamically interact in collective learning between two religious organizations cooperating in a joint project. It further explored the enablers of and impediments to collective learning in this context. The study employed the theoretical framework provided by the Organizational Learning…

Stand By for Fun: Experience and Interaction.

ERIC Educational Resources Information Center

Crockford, Douglas

1986-01-01

This paper explores interactivity, and considers what should be done to create a mass market for interactive media. It is suggested that one way to do so is to examine the video game phenomenon, and a model of interactivity is proposed. The model, a "home interactive theater," would involve interaction in the telling of a story, with the…

The OncoPPi Portal: an integrative resource to explore and prioritize protein-protein interactions for cancer target discovery. | Office of Cancer Genomics

Cancer.gov

Motivation: As cancer genomics initiatives move toward comprehensive identification of genetic alterations in cancer, attention is now turning to understanding how interactions among these genes lead to the acquisition of tumor hallmarks. Emerging pharmacological and clinical data suggest a highly promising role of cancer-specific protein-protein interactions (PPIs) as druggable cancer targets. However, large-scale experimental identification of cancer-related PPIs remains challenging, and currently available resources to explore oncogenic PPI networks are limited.

Factors Promoting Engaged Exploration with Computer Simulations

ERIC Educational Resources Information Center

Podolefsky, Noah S.; Perkins, Katherine K.; Adams, Wendy K.

2010-01-01

This paper extends prior research on student use of computer simulations (sims) to engage with and explore science topics, in this case wave interference. We describe engaged exploration; a process that involves students actively interacting with educational materials, sense making, and exploring primarily via their own questioning. We analyze…

Earthworms, Dirt, and Rotten Leaves: An Exploration in Ecology.

ERIC Educational Resources Information Center

McLaughlin, Molly

1994-01-01

This article provides a model for inviting children to "an exploration in ecology" by observing earthworms. It gives reasons to explore earthworms and guides the investigator through a detailed examination of the worms to answer 21 observation questions. Explores the ways in which earthworms interact with their environment. (LZ)

Scientific Visualization of Radio Astronomy Data using Gesture Interaction

NASA Astrophysics Data System (ADS)

Mulumba, P.; Gain, J.; Marais, P.; Woudt, P.

2015-09-01

MeerKAT in South Africa (Meer = More Karoo Array Telescope) will require software to help visualize, interpret and interact with multidimensional data. While visualization of multi-dimensional data is a well explored topic, little work has been published on the design of intuitive interfaces to such systems. More specifically, the use of non-traditional interfaces (such as motion tracking and multi-touch) has not been widely investigated within the context of visualizing astronomy data. We hypothesize that a natural user interface would allow for easier data exploration which would in turn lead to certain kinds of visualizations (volumetric, multidimensional). To this end, we have developed a multi-platform scientific visualization system for FITS spectral data cubes using VTK (Visualization Toolkit) and a natural user interface to explore the interaction between a gesture input device and multidimensional data space. Our system supports visual transformations (translation, rotation and scaling) as well as sub-volume extraction and arbitrary slicing of 3D volumetric data. These tasks were implemented across three prototypes aimed at exploring different interaction strategies: standard (mouse/keyboard) interaction, volumetric gesture tracking (Leap Motion controller) and multi-touch interaction (multi-touch monitor). A Heuristic Evaluation revealed that the volumetric gesture tracking prototype shows great promise for interfacing with the depth component (z-axis) of 3D volumetric space across multiple transformations. However, this is limited by users needing to remember the required gestures. In comparison, the touch-based gesture navigation is typically more familiar to users as these gestures were engineered from standard multi-touch actions. Future work will address a complete usability test to evaluate and compare the different interaction modalities against the different visualization tasks.

Interactive (statistical) visualisation and exploration of a billion objects with vaex

NASA Astrophysics Data System (ADS)

Breddels, M. A.

2017-06-01

With new catalogues arriving such as the Gaia DR1, containing more than a billion objects, new methods of handling and visualizing these data volumes are needed. We show that by calculating statistics on a regular (N-dimensional) grid, visualizations of a billion objects can be done within a second on a modern desktop computer. This is achieved using memory mapping of hdf5 files together with a simple binning algorithm, which are part of a Python library called vaex. This enables efficient exploration or large datasets interactively, making science exploration of large catalogues feasible. Vaex is a Python library and an application, which allows for interactive exploration and visualization. The motivation for developing vaex is the catalogue of the Gaia satellite, however, vaex can also be used on SPH or N-body simulations, any other (future) catalogues such as SDSS, Pan-STARRS, LSST, etc. or other tabular data. The homepage for vaex is http://vaex.astro.rug.nl.

Causal learning is collaborative: Examining explanation and exploration in social contexts.

PubMed

Legare, Cristine H; Sobel, David M; Callanan, Maureen

2017-10-01

Causal learning in childhood is a dynamic and collaborative process of explanation and exploration within complex physical and social environments. Understanding how children learn causal knowledge requires examining how they update beliefs about the world given novel information and studying the processes by which children learn in collaboration with caregivers, educators, and peers. The objective of this article is to review evidence for how children learn causal knowledge by explaining and exploring in collaboration with others. We review three examples of causal learning in social contexts, which elucidate how interaction with others influences causal learning. First, we consider children's explanation-seeking behaviors in the form of "why" questions. Second, we examine parents' elaboration of meaning about causal relations. Finally, we consider parents' interactive styles with children during free play, which constrains how children explore. We propose that the best way to understand children's causal learning in social context is to combine results from laboratory and natural interactive informal learning environments.

Exploring How White and Asian American Students Experience Cross-Racial Interactions: A Phenomenological Study

ERIC Educational Resources Information Center

Robinson, Thomas E.

2012-01-01

Interracial interactions between college students are responsible for important learning outcomes, however many colleges and universities have failed to purposefully encourage students to interact across racial backgrounds. As a result of a lack purposefully facilitated cross-racial interactions (CRIs), fewer interracial interactions occur on U.S.…

ePlant and the 3D data display initiative: integrative systems biology on the world wide web.

PubMed

Fucile, Geoffrey; Di Biase, David; Nahal, Hardeep; La, Garon; Khodabandeh, Shokoufeh; Chen, Yani; Easley, Kante; Christendat, Dinesh; Kelley, Lawrence; Provart, Nicholas J

2011-01-10

Visualization tools for biological data are often limited in their ability to interactively integrate data at multiple scales. These computational tools are also typically limited by two-dimensional displays and programmatic implementations that require separate configurations for each of the user's computing devices and recompilation for functional expansion. Towards overcoming these limitations we have developed "ePlant" (http://bar.utoronto.ca/eplant) - a suite of open-source world wide web-based tools for the visualization of large-scale data sets from the model organism Arabidopsis thaliana. These tools display data spanning multiple biological scales on interactive three-dimensional models. Currently, ePlant consists of the following modules: a sequence conservation explorer that includes homology relationships and single nucleotide polymorphism data, a protein structure model explorer, a molecular interaction network explorer, a gene product subcellular localization explorer, and a gene expression pattern explorer. The ePlant's protein structure explorer module represents experimentally determined and theoretical structures covering >70% of the Arabidopsis proteome. The ePlant framework is accessed entirely through a web browser, and is therefore platform-independent. It can be applied to any model organism. To facilitate the development of three-dimensional displays of biological data on the world wide web we have established the "3D Data Display Initiative" (http://3ddi.org).

Scaffold explorer: an interactive tool for organizing and mining structure-activity data spanning multiple chemotypes.

PubMed

Agrafiotis, Dimitris K; Wiener, John J M

2010-07-08

We introduce Scaffold Explorer, an interactive tool that allows medicinal chemists to define hierarchies of chemical scaffolds and use them to explore their project data. Scaffold Explorer allows the user to construct a tree, where each node corresponds to a specific scaffold. Each node can have multiple children, each of which represents a more refined substructure relative to its parent node. Once the tree is defined, it can be mapped onto any collection of compounds and be used as a navigational tool to explore structure-activity relationships (SAR) across different chemotypes. The rich visual analytics of Scaffold Explorer afford the user a "bird's-eye" view of the chemical space spanned by a particular data set, map any physicochemical property or biological activity of interest onto the individual scaffold nodes, serve as an aggregator for the properties of the compounds represented by these nodes, and quickly distinguish promising chemotypes from less interesting or problematic ones. Unlike previous approaches, which focused on automated extraction and classification of scaffolds, the utility of the new tool rests on its interactivity and ability to accommodate the medicinal chemists' intuition by allowing the use of arbitrary substructures containing variable atoms, bonds, and/or substituents such as those employed in substructure search.

Let's Tweet in Chinese! Exploring How Learners of Chinese as a Foreign Language Self-Direct Their Use of Microblogging to Learn Chinese

ERIC Educational Resources Information Center

Hsiao, Ya Ping; Broeder, Peter

2014-01-01

Twitter is becoming increasingly popular as a medium for language learning. This study explores self-directed learning via social interactions that use Twitter as an interactive learning environment. The participants in this study were thirty university students of Chinese as a foreign language at levels 1 and 2 of the "Hanyu Shuiping…

An Exploration of the Value Placed on the Content, Interaction and Incentive Dimensions of Learning by Young People in Post-Compulsory Education

ERIC Educational Resources Information Center

Mainwaring, Deborah

2016-01-01

The paper presents the findings of quantitative research that explores the value young people in post-compulsory education in England attach to three dimensions of learning. The dimensions of learning are the content dimension, the interaction dimension and the incentive dimension. Three hundred and thirty-one young people in four post-compulsory…

Exploring the Stability of Gold Nanoparticles by Experimenting with Adsorption Interactions of Nanomaterials in an Undergraduate Lab

ERIC Educational Resources Information Center

Lee, Chi-Feng; You, Pei-Yun; Lin, Ying-Chiao; Hsu, Tsai-Ling; Cheng, Pi-Yun; Wu, Yu-Xuan; Tseng, Chi-Shun; Chen, Sheng-Wen; Chang, Huey-Por; Lin, Yang-Wei

2015-01-01

The proposed experiment can help students to understand the factors involved in the stability of gold nanoparticles (Au NPs) by exploring the adsorption interaction between Au NPs and various substances. The students in this study found that the surface plasmon resonance band of Au NP solutions underwent a red shift (i.e., from 520 to 650 nm)…

Dynamic Interactive Learning Systems

ERIC Educational Resources Information Center

Sabry, Khaled; Barker, Jeff

2009-01-01

This paper reviews and discusses the notions of interactivity and dynamicity of learning systems in relation to information technologies and design principles that can contribute to interactive and dynamic learning. It explores the concept of dynamic interactive learning systems based on the emerging generation of information as part of a…

Exploring the requirements for multimodal interaction for mobile devices in an end-to-end journey context.

PubMed

Krehl, Claudia; Sharples, Sarah

2012-01-01

The paper investigates the requirements for multimodal interaction on mobile devices in an end-to-end journey context. Traditional interfaces are deemed cumbersome and inefficient for exchanging information with the user. Multimodal interaction provides a different user-centred approach allowing for more natural and intuitive interaction between humans and computers. It is especially suitable for mobile interaction as it can overcome additional constraints including small screens, awkward keypads, and continuously changing settings - an inherent property of mobility. This paper is based on end-to-end journeys where users encounter several contexts during their journeys. Interviews and focus groups explore the requirements for multimodal interaction design for mobile devices by examining journey stages and identifying the users' information needs and sources. Findings suggest that multimodal communication is crucial when users multitask. Choosing suitable modalities depend on user context, characteristics and tasks.

Exploring hydride-π interactions and their tuning by σ-hole bonds: an ab initio study

NASA Astrophysics Data System (ADS)

Esrafili, Mehdi D.; Asadollahi, Soheila; Mousavian, Parisasadat

2018-01-01

In the present work, ab initio calculations are performed to investigate the geometry, interaction energy and bonding properties of binary complexes formed between metal-hydrides HMX (M = Be, Mg, Zn and X = H, F, CH3) and a series of π-acidic heteroaromatic rings. In all the resulting complexes, the heteroaromatic ring acts as a Lewis acid (electron acceptor), while the H atom of the HMX molecule acts as a Lewis base (electron donor). The nature of this interaction, called 'hydride-π' interaction, is explored in terms of molecular electrostatic potential, non-covalent interaction, quantum theory of atoms in molecules and natural bond orbital analyses. The results show that the interaction energies of these hydride-π interactions are between -1.24 and -2.72 kcal/mol. Furthermore, mutual influence between the hydride-π and halogen- or pnicogen-bonding interactions is studied in complexes in which these interactions coexist. For a given π-acidic ring, the formation of the pnicogen-bonding induces a larger enhancing effect on the strength of hydride-π bond than the halogen-bonding.

MaGnET: Malaria Genome Exploration Tool.

PubMed

Sharman, Joanna L; Gerloff, Dietlind L

2013-09-15

The Malaria Genome Exploration Tool (MaGnET) is a software tool enabling intuitive 'exploration-style' visualization of functional genomics data relating to the malaria parasite, Plasmodium falciparum. MaGnET provides innovative integrated graphic displays for different datasets, including genomic location of genes, mRNA expression data, protein-protein interactions and more. Any selection of genes to explore made by the user is easily carried over between the different viewers for different datasets, and can be changed interactively at any point (without returning to a search). Free online use (Java Web Start) or download (Java application archive and MySQL database; requires local MySQL installation) at http://malariagenomeexplorer.org joanna.sharman@ed.ac.uk or dgerloff@ffame.org Supplementary data are available at Bioinformatics online.

Exploring social structure effect on language evolution based on a computational model

NASA Astrophysics Data System (ADS)

Gong, Tao; Minett, James; Wang, William

2008-06-01

A compositionality-regularity coevolution model is adopted to explore the effect of social structure on language emergence and maintenance. Based on this model, we explore language evolution in three experiments, and discuss the role of a popular agent in language evolution, the relationship between mutual understanding and social hierarchy, and the effect of inter-community communications and that of simple linguistic features on convergence of communal languages in two communities. This work embodies several important interactions during social learning, and introduces a new approach that manipulates individuals' probabilities to participate in social interactions to study the effect of social structure. We hope it will stimulate further theoretical and empirical explorations on language evolution in a social environment.

Modeled interactive effects of precipitation, temperature, and [CO2] on ecosystem carbon and water dynamics in different climatic zones

Treesearch

Yiqi Luo; Dieter Gerten; Guerric Le Maire; William J. Parton; Ensheng Weng; Xuhui Zhou; Cindy Keough; Claus Beier; Philippe Ciais; Wolfgang Cramer; Jeffrey S. Dukes; Bridget Emmett; Paul J. Hanson; Alan Knapp; Sune Linder; Dan Nepstad; Lindsey. Rustad

2008-01-01

Interactive effects of multiple global change factors on ecosystem processes are complex. It is relatively expensive to explore those interactions in manipulative experiments. We conducted a modeling analysis to identify potentially important interactions and to stimulate hypothesis formulation for experimental research. Four models were used to quantify interactive...

Interpreting Parent-Infant Interactions: Cross-Cultural Lessons.

ERIC Educational Resources Information Center

McCollum, Jeanette A.; Ree, Yon; Chen, Yu-Jun

2000-01-01

Drawing on interviews with six American and Korean mothers, this article explores the range and coalescence of ideas that mothers from different cultures have about interactions with their 12-month-old babies in social interactive play and joint play with objects. Differences and similarities about the mothers' ideas about interaction are…

"Interactive Whole Class Teaching" in the National Literacy Strategy.

ERIC Educational Resources Information Center

Hardman, Frank; Smith, Fay; Wall, Kate

2003-01-01

Presents findings of extensive investigation (n=70) into interactive and discourse styles of a nationally representative sample of primary teachers. Explores impact of official endorsement of interactive whole class teaching in the teaching of England's National Literacy Strategy to examine whether it is promoting pupils' higher interaction and…

On the Rhetorical Contract in Human-Computer Interaction.

ERIC Educational Resources Information Center

Wenger, Michael J.

1991-01-01

An exploration of the rhetorical contract--i.e., the expectations for appropriate interaction--as it develops in human-computer interaction revealed that direct manipulation interfaces were more likely to establish social expectations. Study results suggest that the social nature of human-computer interactions can be examined with reference to the…

Interaction Forms in Successful Collaborative Learning in Virtual Learning Environments

ERIC Educational Resources Information Center

Vuopala, Essi; Hyvönen, Pirkko; Järvelä, Sanna

2016-01-01

Despite the numerous studies on social interaction in collaborative learning, little is known about interaction forms in successful computer-supported collaborative learning situations. The purpose of this study was to explore and understand student interaction in successful collaborative learning during a university course which was mediated by…

Examining the Educational Benefits of Interacting with International Students

ERIC Educational Resources Information Center

Luo, Jiali; Jamieson-Drake, David

2013-01-01

Through the analysis of alumni survey data from three graduating cohorts, this study examined the influence of interaction with international students on domestic students' college outcomes and explored factors that helped to promote international interaction on college campuses. The findings indicate that in comparison to non-interactive domestic…

Brief Report: Patterns of Eye Movements in Face to Face Conversation are Associated with Autistic Traits: Evidence from a Student Sample.

PubMed

Vabalas, Andrius; Freeth, Megan

2016-01-01

The current study investigated whether the amount of autistic traits shown by an individual is associated with viewing behaviour during a face-to-face interaction. The eye movements of 36 neurotypical university students were recorded using a mobile eye-tracking device. High amounts of autistic traits were neither associated with reduced looking to the social partner overall, nor with reduced looking to the face. However, individuals who were high in autistic traits exhibited reduced visual exploration during the face-to-face interaction overall, as demonstrated by shorter and less frequent saccades. Visual exploration was not related to social anxiety. This study suggests that there are systematic individual differences in visual exploration during social interactions and these are related to amount of autistic traits.

Streptomyces exploration is triggered by fungal interactions and volatile signals.

PubMed

Jones, Stephanie E; Ho, Louis; Rees, Christiaan A; Hill, Jane E; Nodwell, Justin R; Elliot, Marie A

2017-01-03

It has long been thought that the life cycle of Streptomyces bacteria encompasses three developmental stages: vegetative hyphae, aerial hyphae and spores. Here, we show interactions between Streptomyces and fungi trigger a previously unobserved mode of Streptomyces development. We term these Streptomyces cells 'explorers', for their ability to adopt a non-branching vegetative hyphal conformation and rapidly transverse solid surfaces. Fungi trigger Streptomyces exploratory growth in part by altering the composition of the growth medium, and Streptomyces explorer cells can communicate this exploratory behaviour to other physically separated streptomycetes using an airborne volatile organic compound (VOC). These results reveal that interkingdom interactions can trigger novel developmental behaviours in bacteria, here, causing Streptomyces to deviate from its classically-defined life cycle. Furthermore, this work provides evidence that VOCs can act as long-range communication signals capable of propagating microbial morphological switches.

Interactive Streamline Exploration and Manipulation Using Deformation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tong, Xin; Chen, Chun-Ming; Shen, Han-Wei

2015-01-12

Occlusion presents a major challenge in visualizing three-dimensional flow fields with streamlines. Displaying too many streamlines at once makes it difficult to locate interesting regions, but displaying too few streamlines risks missing important features. A more ideal streamline exploration model is to allow the viewer to freely move across the field that has been populated with interesting streamlines and pull away the streamlines that cause occlusion so that the viewer can inspect the hidden ones in detail. In this paper, we present a streamline deformation algorithm that supports such user-driven interaction with three-dimensional flow fields. We define a view-dependent focus+contextmore » technique that moves the streamlines occluding the focus area using a novel displacement model. To preserve the context surrounding the user-chosen focus area, we propose two shape models to define the transition zone for the surrounding streamlines, and the displacement of the contextual streamlines is solved interactively with a goal of preserving their shapes as much as possible. Based on our deformation model, we design an interactive streamline exploration tool using a lens metaphor. Our system runs interactively so that users can move their focus and examine the flow field freely.« less

Opportunities and Challenges of Implementing Instructional Games in Mathematics Classrooms: Examining the Quality of Teacher-Student Interactions during the Cover-Up and Un-Cover Games

ERIC Educational Resources Information Center

Heshmati, Saeideh; Kersting, Nicole; Sutton, Taliesin

2018-01-01

This study explored the design and implementation of the Cover-up and Un-cover games, two manipulative-based fraction games, in 14 fifth-grade classrooms. We examined how the fraction concepts were integrated into the game design and explored the nature of teacher-student interactions during games using lesson videos. Our examination showed that…

PDB-Explorer: a web-based interactive map of the protein data bank in shape space.

PubMed

Jin, Xian; Awale, Mahendra; Zasso, Michaël; Kostro, Daniel; Patiny, Luc; Reymond, Jean-Louis

2015-10-23

The RCSB Protein Data Bank (PDB) provides public access to experimentally determined 3D-structures of biological macromolecules (proteins, peptides and nucleic acids). While various tools are available to explore the PDB, options to access the global structural diversity of the entire PDB and to perceive relationships between PDB structures remain very limited. A 136-dimensional atom pair 3D-fingerprint for proteins (3DP) counting categorized atom pairs at increasing through-space distances was designed to represent the molecular shape of PDB-entries. Nearest neighbor searches examples were reported exemplifying the ability of 3DP-similarity to identify closely related biomolecules from small peptides to enzyme and large multiprotein complexes such as virus particles. The principle component analysis was used to obtain the visualization of PDB in 3DP-space. The 3DP property space groups proteins and protein assemblies according to their 3D-shape similarity, yet shows exquisite ability to distinguish between closely related structures. An interactive website called PDB-Explorer is presented featuring a color-coded interactive map of PDB in 3DP-space. Each pixel of the map contains one or more PDB-entries which are directly visualized as ribbon diagrams when the pixel is selected. The PDB-Explorer website allows performing 3DP-nearest neighbor searches of any PDB-entry or of any structure uploaded as protein-type PDB file. All functionalities on the website are implemented in JavaScript in a platform-independent manner and draw data from a server that is updated daily with the latest PDB additions, ensuring complete and up-to-date coverage. The essentially instantaneous 3DP-similarity search with the PDB-Explorer provides results comparable to those of much slower 3D-alignment algorithms, and automatically clusters proteins from the same superfamilies in tight groups. A chemical space classification of PDB based on molecular shape was obtained using a new atom-pair 3D-fingerprint for proteins and implemented in a web-based database exploration tool comprising an interactive color-coded map of the PDB chemical space and a nearest neighbor search tool. The PDB-Explorer website is freely available at www.cheminfo.org/pdbexplorer and represents an unprecedented opportunity to interactively visualize and explore the structural diversity of the PDB. ᅟ

An ESA roadmap for geobiology in space exploration

NASA Astrophysics Data System (ADS)

Cousins, Claire R.; Cockell, Charles S.

2016-01-01

Geobiology, and in particular mineral-microbe interactions, has a significant role to play in current and future space exploration. This includes the search for biosignatures in extraterrestrial environments, and the human exploration of space. Microorganisms can be exploited to advance such exploration, such as through biomining, maintenance of life-support systems, and testing of life-detection instrumentation. In view of these potential applications, a European Space Agency (ESA) Topical Team "Geobiology in Space Exploration" was developed to explore these applications, and identify research avenues to be investigated to support this endeavour. Through community workshops, a roadmap was produced, with which to define future research directions via a set of 15 recommendations spanning three key areas: Science, Technology, and Community. These roadmap recommendations identify the need for research into: (1) new terrestrial space-analogue environments; (2) community level microbial-mineral interactions; (3) response of biofilms to the space environment; (4) enzymatic and biochemical mineral interaction; (5) technical refinement of instrumentation for space-based microbiology experiments, including precursor flight tests; (6) integration of existing ground-based planetary simulation facilities; (7) integration of fieldsite biogeography with laboratory- and field-based research; (8) modification of existing planetary instruments for new geobiological investigations; (9) development of in situ sample preparation techniques; (10) miniaturisation of existing analytical methods, such as DNA sequencing technology; (11) new sensor technology to analyse chemical interaction in small volume samples; (12) development of reusable Lunar and Near Earth Object experimental platforms; (13) utility of Earth-based research to enable the realistic pursuit of extraterrestrial biosignatures; (14) terrestrial benefits and technological spin-off from existing and future space-based geobiology investigations; and (15) new communication avenues between space agencies and terrestrial research organisations to enable this impact to be developed.

Anxiety and Career Exploration: Gender Differences in the Role of Self-Construal

ERIC Educational Resources Information Center

Hardin, Erin E.; Varghese, Femina P.; Tran, Uyen V.; Carlson, Aaron Z.

2006-01-01

Given the social nature of many tasks involved in exploring and committing to a career, we hypothesized that social anxiety would correlate to exploration and commitment, even after controlling for general anxiety. We also hypothesized that self-construal and gender would interact with social anxiety in relation to exploration and commitment. In a…

An exploration of motivations for two screen viewing, social interaction behaviors, and factors that influence viewing intentions.

PubMed

Shim, Hongjin; Oh, Poong; Song, Hyunjin; Lee, Yeonkyung

2015-03-01

This study explores whether, and how, motivations for two screen viewing predicted social interaction behaviors and subsequent viewing intention of TV programs. A total of 453 respondents who responded that they use social networking sites (SNSs) via smartphones and actively watch entertainment programs completed an online survey questionnaire. In agreement with uses and gratifications assumptions, motivations for TSV predicted distinctive sets of social interaction behaviors, which mediated the influence of motivations on viewing intentions. Respondents' two screen viewing was meaningfully related with social interaction, engagement with programs, information seeking, and passing time. Results suggest that two screen viewing could provide shared experiences nourishing social capital and reintegrate TV audiences by social adhesive resulting from TV with SNSs.

Ionic Impurity in a Bose-Einstein Condensate at Submicrokelvin Temperatures

NASA Astrophysics Data System (ADS)

Kleinbach, K. S.; Engel, F.; Dieterle, T.; Löw, R.; Pfau, T.; Meinert, F.

2018-05-01

Rydberg atoms immersed in a Bose-Einstein condensate interact with the quantum gas via electron-atom and ion-atom interaction. To suppress the typically dominant electron-neutral interaction, Rydberg states with a principal quantum number up to n =190 are excited from a dense and tightly trapped micron-sized condensate. This allows us to explore a regime where the Rydberg orbit exceeds the size of the atomic sample by far. In this case, a detailed line shape analysis of the Rydberg excitation spectrum provides clear evidence for ion-atom interaction at temperatures well below a microkelvin. Our results may open up ways to enter the quantum regime of ion-atom scattering for the exploration of charged quantum impurities and associated polaron physics.

Mother-Father-Newborn Interaction: Effects of Maternal Medication, Labor, and Sex of Infant.

ERIC Educational Resources Information Center

Parke, Ross D.; And Others

A research study was conducted to: (1) compare mother and father interactions with their newborn infant; (2) examine the effects of maternal drugs on mother-father infant interaction; (3) explore the impact of variations in length of labor on parent interaction; and (4) examine sex of parent and sex of newborn interactions to determine the nature…

Measuring L2 Speakers' Interactional Ability Using Interactive Speech Tasks

ERIC Educational Resources Information Center

van Batenburg, Eline S. L.; Oostdam, Ron J.; van Gelderen, Amos J. S.; de Jong, Nivja H.

2018-01-01

This article explores ways to assess interactional performance, and reports on the use of a test format that standardizes the interlocutor's linguistic and interactional contributions to the exchange. It describes the construction and administration of six scripted speech tasks (instruction, advice, and sales tasks) with pre-vocational learners (n…

The Student-Faculty Relationship: An Investigation of the Interactions between Students and Faculty

ERIC Educational Resources Information Center

Ross, Justin Meredith

2013-01-01

The purpose of this study was to explore the subjective perceptions held by students of their interactions with faculty members in college, especially as those interactions relate to the integration and membership of students in the academic community. Academic integration, resulting primarily from student-faculty interactions, has been theorized…

Turkish Mothers' Self-Efficacy Beliefs and Styles of Interactions with Their Children with Language Delays

ERIC Educational Resources Information Center

Diken, Ibrahim H.

2009-01-01

Turkish mothers' self-efficacy beliefs and their interactional behaviors with their children with language delays are described and explored. Participants included 19 mother-child dyads. Mothers' interaction with their children with language delays was videotaped for 30 minutes in a free-play context. Regarding mothers' interactional behaviors,…

Alternative Breaks as a Context for Informal Interactions with Diversity

ERIC Educational Resources Information Center

Niehaus, Elizabeth

2016-01-01

One of the most frequently touted benefits of higher education is the opportunity to interact with people different from oneself, yet these interactions do not automatically lead to positive outcomes. The purpose of this study is to explore how one particular context for diversity interactions, service-based alternative break programs, may provide…

From Virtual Environments to Physical Environments: Exploring Interactivity in Ubiquitous-Learning Systems

ERIC Educational Resources Information Center

Peng, Hsinyi; Chou, Chien; Chang, Chun-Yu

2008-01-01

Computing devices and applications are now used beyond the desktop, in diverse environments, and this trend toward ubiquitous computing is evolving. In this study, we re-visit the interactivity concept and its applications for interactive function design in a ubiquitous-learning system (ULS). Further, we compare interactivity dimensions and…

Harnessing the Power of Interactivity for Instruction.

ERIC Educational Resources Information Center

Borsook, Terry K.

Arguing that what sets the computer apart from all other teaching devices is its potential for interactivity, this paper examines the concept of interactivity and explores ways in which its power can be harnessed and put to work. A discussion of interactivity in human-to-human communication sets a context within which to view human/computer…

When Norms Are Violated: Imagined Interactions as Processing and Coping Mechanisms.

ERIC Educational Resources Information Center

Berkos, Kristen M.; Allen, Terre H.; Kearney, Patricia; Plax, Timothy G.

2001-01-01

Explores undergraduate student receivers' symbolic cognitive processes in response to particular types of norm violations. Finds that imagined interactions were used in respect to all three types of violations profiled and that participants were significantly more likely to engage in imagined interactions than to interact with or confront norm…

ESL Students' Interaction in Second Life: Task-Based Synchronous Computer-Mediated Communication

ERIC Educational Resources Information Center

Jee, Min Jung

2010-01-01

The purpose of the present study was to explore ESL students' interactions in task-based synchronous computer-mediated communication (SCMC) in Second Life, a virtual environment by which users can interact through representational figures. I investigated Low-Intermediate and High-Intermediate ESL students' interaction patterns before, during, and…

Interaction and the Online Distance Classroom: Do Instructional Methods Effect the Quality of Interaction?

ERIC Educational Resources Information Center

Kanuka, Heather

2011-01-01

In this special issue, I bring together two studies to provide a comprehensive overview on diverse and interactive instructional methods aimed to facilitate higher levels of learning. One study explored the effects of group interaction using different instructional strategies focusing on the learning "process" using the Community of Inquiry…

How will biotic interactions influence climate change-induced range shifts?

PubMed

HilleRisLambers, Janneke; Harsch, Melanie A; Ettinger, Ailene K; Ford, Kevin R; Theobald, Elinore J

2013-09-01

Biotic interactions present a challenge in determining whether species distributions will track climate change. Interactions with competitors, consumers, mutualists, and facilitators can strongly influence local species distributions, but few studies assess how and whether these interactions will impede or accelerate climate change-induced range shifts. In this paper, we explore how ecologists might move forward on this question. We first outline the conditions under which biotic interactions can result in range shifts that proceed faster or slower than climate velocity and result in ecological surprises. Next, we use our own work to demonstrate that experimental studies documenting the strength of biotic interactions across large environmental gradients are a critical first step for understanding whether they will influence climate change-induced range shifts. Further progress could be made by integrating results from these studies into modeling frameworks to predict how or generalize when biotic interactions mediate how changing climates influence range shifts. Finally, we argue that many more case studies like those described here are needed to explore the importance of biotic interactions during climate change-induced range shifts. © 2013 New York Academy of Sciences.

MTVis: tree exploration using a multitouch interface

NASA Astrophysics Data System (ADS)

Andrews, David; Teoh, Soon Tee

2010-01-01

We present MTVis, a multi-touch interactive tree visualization system. The multi-touch interface display hardware is built using the LED-LP technology, and the tree layout is based on RINGS, but enhanced with multitouch interactions. We describe the features of the system, and how the multi-touch interface enhances the user's experience in exploring the tree data structure. In particular, the multi-touch interface allows the user to simultaneously control two child nodes of the root, and rotate them so that some nodes are magnified, while preserving the layout of the tree. We also describe the other meaninful touch screen gestures the users can use to intuitively explore the tree.

Screen and clean: a tool for identifying interactions in genome-wide association studies.

PubMed

Wu, Jing; Devlin, Bernie; Ringquist, Steven; Trucco, Massimo; Roeder, Kathryn

2010-04-01

Epistasis could be an important source of risk for disease. How interacting loci might be discovered is an open question for genome-wide association studies (GWAS). Most researchers limit their statistical analyses to testing individual pairwise interactions (i.e., marginal tests for association). A more effective means of identifying important predictors is to fit models that include many predictors simultaneously (i.e., higher-dimensional models). We explore a procedure called screen and clean (SC) for identifying liability loci, including interactions, by using the lasso procedure, which is a model selection tool for high-dimensional regression. We approach the problem by using a varying dictionary consisting of terms to include in the model. In the first step the lasso dictionary includes only main effects. The most promising single-nucleotide polymorphisms (SNPs) are identified using a screening procedure. Next the lasso dictionary is adjusted to include these main effects and the corresponding interaction terms. Again, promising terms are identified using lasso screening. Then significant terms are identified through the cleaning process. Implementation of SC for GWAS requires algorithms to explore the complex model space induced by the many SNPs genotyped and their interactions. We propose and explore a set of algorithms and find that SC successfully controls Type I error while yielding good power to identify risk loci and their interactions. When the method is applied to data obtained from the Wellcome Trust Case Control Consortium study of Type 1 Diabetes it uncovers evidence supporting interaction within the HLA class II region as well as within Chromosome 12q24.

An autoethnographic exploration of the use of goal oriented feedback to enhance brief clinical teaching encounters.

PubMed

Farrell, Laura; Bourgeois-Law, Gisele; Ajjawi, Rola; Regehr, Glenn

2017-03-01

Supervision in the outpatient context is increasingly in the form of single day interactions between students and preceptors. This creates difficulties for effective feedback, which often depends on a strong relationship of trust between preceptor and student. Building on feedback theories focusing on the relational and dialogic aspects of feedback, this study explored the use of goal-oriented feedback in brief encounters with learners. This study used autoethnography to explore one preceptor's feedback interactions over an eight-month period both in the ambulatory setting and on the wards. Data included written narrative reflections on feedback interactions with twenty-three learners informed by discussions with colleagues and repeated reading of feedback literature. Thematic and narrative analyses of data were performed iteratively. Data analysis emphasized four recurrent themes. (1) Goal discussions were most effective when initiated early and integrated throughout the learning experience. (2) Both learner and preceptor goals were multiple and varied, and feedback needed to reflect this complexity. (3) Negotiation or co-construction of goals was important when considering the focus of feedback discussions in order to create safer, more effective interactions. (4) Goal oriented interactions offer potential benefits to the learner and preceptor. Goal oriented feedback promotes dialogue as it requires both preceptor and learner to acknowledge and negotiate learning goals throughout their interaction. In doing so, feedback becomes an explicit component of the preceptor-learner relationship. This enhances feedback interactions even in relatively brief encounters, and may begin an early educational alliance that can be elaborated with longer interactions.

Interactive Data Exploration with Smart Drill-Down

PubMed Central

Joglekar, Manas; Garcia-Molina, Hector; Parameswaran, Aditya

2017-01-01

We present smart drill-down, an operator for interactively exploring a relational table to discover and summarize “interesting” groups of tuples. Each group of tuples is described by a rule. For instance, the rule (a, b, ⋆, 1000) tells us that there are a thousand tuples with value a in the first column and b in the second column (and any value in the third column). Smart drill-down presents an analyst with a list of rules that together describe interesting aspects of the table. The analyst can tailor the definition of interesting, and can interactively apply smart drill-down on an existing rule to explore that part of the table. We demonstrate that the underlying optimization problems are NP-Hard, and describe an algorithm for finding the approximately optimal list of rules to display when the user uses a smart drill-down, and a dynamic sampling scheme for efficiently interacting with large tables. Finally, we perform experiments on real datasets on our experimental prototype to demonstrate the usefulness of smart drill-down and study the performance of our algorithms. PMID:28210096

Tunable-Range, Photon-Mediated Atomic Interactions in Multimode Cavity QED

NASA Astrophysics Data System (ADS)

Vaidya, Varun D.; Guo, Yudan; Kroeze, Ronen M.; Ballantine, Kyle E.; Kollár, Alicia J.; Keeling, Jonathan; Lev, Benjamin L.

2018-01-01

Optical cavity QED provides a platform with which to explore quantum many-body physics in driven-dissipative systems. Single-mode cavities provide strong, infinite-range photon-mediated interactions among intracavity atoms. However, these global all-to-all couplings are limiting from the perspective of exploring quantum many-body physics beyond the mean-field approximation. The present work demonstrates that local couplings can be created using multimode cavity QED. This is established through measurements of the threshold of a superradiant, self-organization phase transition versus atomic position. Specifically, we experimentally show that the interference of near-degenerate cavity modes leads to both a strong and tunable-range interaction between Bose-Einstein condensates (BECs) trapped within the cavity. We exploit the symmetry of a confocal cavity to measure the interaction between real BECs and their virtual images without unwanted contributions arising from the merger of real BECs. Atom-atom coupling may be tuned from short range to long range. This capability paves the way toward future explorations of exotic, strongly correlated systems such as quantum liquid crystals and driven-dissipative spin glasses.

Development of Support Service for Prevention and Recovery from Dementia and Science of Lethe

NASA Astrophysics Data System (ADS)

Otake, Mihoko

Purpose of this study is to explore service design method through the development of support service for prevention and recovery from dementia towards science of lethe. We designed and implemented conversation support service via coimagination method based on multiscale service design method, both were proposed by the author. Multiscale service model consists of tool, event, human, network, style and rule. Service elements at different scales are developed according to the model. Interactive conversation supported by coimagination method activates cognitive functions so as to prevent progress of dementia. This paper proposes theoretical bases for science of lethe. Firstly, relationship among coimagination method and three cognitive functions including division of attention, planning, episodic memory which decline at mild cognitive imparement. Secondly, thought state transition model during conversation which describes cognitive enhancement via interactive communication. Thirdly, Set Theoretical Measure of Interaction is proposed for evaluating effectiveness of conversation to cognitive enhancement. Simulation result suggests that the ideas which cannot be explored by each speaker are explored during interactive conversation. Finally, coimagination method compared with reminiscence therapy and its possibility for collaboration is discussed.

Discriminative latent models for recognizing contextual group activities.

PubMed

Lan, Tian; Wang, Yang; Yang, Weilong; Robinovitch, Stephen N; Mori, Greg

2012-08-01

In this paper, we go beyond recognizing the actions of individuals and focus on group activities. This is motivated from the observation that human actions are rarely performed in isolation; the contextual information of what other people in the scene are doing provides a useful cue for understanding high-level activities. We propose a novel framework for recognizing group activities which jointly captures the group activity, the individual person actions, and the interactions among them. Two types of contextual information, group-person interaction and person-person interaction, are explored in a latent variable framework. In particular, we propose three different approaches to model the person-person interaction. One approach is to explore the structures of person-person interaction. Differently from most of the previous latent structured models, which assume a predefined structure for the hidden layer, e.g., a tree structure, we treat the structure of the hidden layer as a latent variable and implicitly infer it during learning and inference. The second approach explores person-person interaction in the feature level. We introduce a new feature representation called the action context (AC) descriptor. The AC descriptor encodes information about not only the action of an individual person in the video, but also the behavior of other people nearby. The third approach combines the above two. Our experimental results demonstrate the benefit of using contextual information for disambiguating group activities.

Discriminative Latent Models for Recognizing Contextual Group Activities

PubMed Central

Lan, Tian; Wang, Yang; Yang, Weilong; Robinovitch, Stephen N.; Mori, Greg

2012-01-01

In this paper, we go beyond recognizing the actions of individuals and focus on group activities. This is motivated from the observation that human actions are rarely performed in isolation; the contextual information of what other people in the scene are doing provides a useful cue for understanding high-level activities. We propose a novel framework for recognizing group activities which jointly captures the group activity, the individual person actions, and the interactions among them. Two types of contextual information, group-person interaction and person-person interaction, are explored in a latent variable framework. In particular, we propose three different approaches to model the person-person interaction. One approach is to explore the structures of person-person interaction. Differently from most of the previous latent structured models, which assume a predefined structure for the hidden layer, e.g., a tree structure, we treat the structure of the hidden layer as a latent variable and implicitly infer it during learning and inference. The second approach explores person-person interaction in the feature level. We introduce a new feature representation called the action context (AC) descriptor. The AC descriptor encodes information about not only the action of an individual person in the video, but also the behavior of other people nearby. The third approach combines the above two. Our experimental results demonstrate the benefit of using contextual information for disambiguating group activities. PMID:22144516

Structural Exploration and Conformational Transitions in MDM2 upon DHFR Interaction from Homo sapiens: A Computational Outlook for Malignancy via Epigenetic Disruption.

PubMed

Banerjee, Arundhati; Ray, Sujay

2016-01-01

Structural basis for exploration into MDM2 and MDM2-DHFR interaction plays a vital role in analyzing the obstruction in folate metabolism, nonsynthesis of purines, and further epigenetic regulation in Homo sapiens. Therefore, it leads to suppression of normal cellular behavior and malignancy. This has been earlier documented via yeast two-hybrid assays. So, with a novel outlook, this study explores the molecular level demonstration of the best satisfactory MDM2 model selection after performing manifold modeling techniques. Z-scores and other stereochemical features were estimated for comparison. Further, protein-protein docking was executed with MDM2 and the experimentally validated X-ray crystallographic DHFR. Residual disclosure from the best suited simulated protein complex disclosed 18 side chain and 3 ionic interactions to strongly accommodate MDM2 protein into the pocket-like zone in DHFR due to the positive environment by charged residues. Lysine residues from MDM2 played a predominant role. Moreover, evaluation from varied energy calculations, folding rate, and net area for solvent accessibility implied the active participation of MDM2 with DHFR. Fascinatingly, conformational transitions from coils to helices and β-sheets after interaction with DHFR affirm the conformational strength and firmer interaction of human MDM2-DHFR. Therefore, this probe instigates near-future clinical research and interactive computational investigations with mutations.

Structural Exploration and Conformational Transitions in MDM2 upon DHFR Interaction from Homo sapiens: A Computational Outlook for Malignancy via Epigenetic Disruption

PubMed Central

Banerjee, Arundhati; Ray, Sujay

2016-01-01

Structural basis for exploration into MDM2 and MDM2-DHFR interaction plays a vital role in analyzing the obstruction in folate metabolism, nonsynthesis of purines, and further epigenetic regulation in Homo sapiens. Therefore, it leads to suppression of normal cellular behavior and malignancy. This has been earlier documented via yeast two-hybrid assays. So, with a novel outlook, this study explores the molecular level demonstration of the best satisfactory MDM2 model selection after performing manifold modeling techniques. Z-scores and other stereochemical features were estimated for comparison. Further, protein-protein docking was executed with MDM2 and the experimentally validated X-ray crystallographic DHFR. Residual disclosure from the best suited simulated protein complex disclosed 18 side chain and 3 ionic interactions to strongly accommodate MDM2 protein into the pocket-like zone in DHFR due to the positive environment by charged residues. Lysine residues from MDM2 played a predominant role. Moreover, evaluation from varied energy calculations, folding rate, and net area for solvent accessibility implied the active participation of MDM2 with DHFR. Fascinatingly, conformational transitions from coils to helices and β-sheets after interaction with DHFR affirm the conformational strength and firmer interaction of human MDM2-DHFR. Therefore, this probe instigates near-future clinical research and interactive computational investigations with mutations. PMID:27213086

A method to explore the quantitative interactions between metal and ceria for M/CeO2 catalysts

NASA Astrophysics Data System (ADS)

Zhu, Kong-Jie; Liu, Jie; Yang, Yan-Ju; Xu, Yu-Xing; Teng, Bo-Tao; Wen, Xiao-Dong; Fan, Maohong

2018-03-01

To explore the quantitative relationship of metal interaction with ceria plays a key role in the theoretical design of M/CeO2 catalysts, especially for the new hot topic of atomically dispersed catalysts. A method to quantitatively explore the interactions between metal and ceria is proposed in the present work on the basis of the qualitative analysis of the effects of different factors on metal adsorption at different ceria surfaces by using Ag/CeO2 as a case. Two parameters are firstly presented, Ep which converts the total adsorption energy into the interaction energy per Agsbnd O bond, and θdiff which measures the deviation of Agsbnd Osbnd Ce bond angle from the angle of the sp3 orbital hybridization of O atom. Using the two parameters, the quantitative relationship of the interaction energy between Ag and ceria is established. There is a linear correlation between Ep and dAgsbndO with θdiff. The higher θdiff, the weaker Ep, and the longer Agsbnd O bond. This method is also suitable for other metals (Cu, Ni, Pd, and Rh, etc.) on ceria. It is the first time to establish the quantitative relationship for the interaction between metal and ceria, and sheds light into the theoretical design of M/CeO2 catalysts.

NaviCell: a web-based environment for navigation, curation and maintenance of large molecular interaction maps

PubMed Central

2013-01-01

Background Molecular biology knowledge can be formalized and systematically represented in a computer-readable form as a comprehensive map of molecular interactions. There exist an increasing number of maps of molecular interactions containing detailed and step-wise description of various cell mechanisms. It is difficult to explore these large maps, to organize discussion of their content and to maintain them. Several efforts were recently made to combine these capabilities together in one environment, and NaviCell is one of them. Results NaviCell is a web-based environment for exploiting large maps of molecular interactions, created in CellDesigner, allowing their easy exploration, curation and maintenance. It is characterized by a combination of three essential features: (1) efficient map browsing based on Google Maps; (2) semantic zooming for viewing different levels of details or of abstraction of the map and (3) integrated web-based blog for collecting community feedback. NaviCell can be easily used by experts in the field of molecular biology for studying molecular entities of interest in the context of signaling pathways and crosstalk between pathways within a global signaling network. NaviCell allows both exploration of detailed molecular mechanisms represented on the map and a more abstract view of the map up to a top-level modular representation. NaviCell greatly facilitates curation, maintenance and updating the comprehensive maps of molecular interactions in an interactive and user-friendly fashion due to an imbedded blogging system. Conclusions NaviCell provides user-friendly exploration of large-scale maps of molecular interactions, thanks to Google Maps and WordPress interfaces, with which many users are already familiar. Semantic zooming which is used for navigating geographical maps is adopted for molecular maps in NaviCell, making any level of visualization readable. In addition, NaviCell provides a framework for community-based curation of maps. PMID:24099179

NaviCell: a web-based environment for navigation, curation and maintenance of large molecular interaction maps.

PubMed

Kuperstein, Inna; Cohen, David P A; Pook, Stuart; Viara, Eric; Calzone, Laurence; Barillot, Emmanuel; Zinovyev, Andrei

2013-10-07

Molecular biology knowledge can be formalized and systematically represented in a computer-readable form as a comprehensive map of molecular interactions. There exist an increasing number of maps of molecular interactions containing detailed and step-wise description of various cell mechanisms. It is difficult to explore these large maps, to organize discussion of their content and to maintain them. Several efforts were recently made to combine these capabilities together in one environment, and NaviCell is one of them. NaviCell is a web-based environment for exploiting large maps of molecular interactions, created in CellDesigner, allowing their easy exploration, curation and maintenance. It is characterized by a combination of three essential features: (1) efficient map browsing based on Google Maps; (2) semantic zooming for viewing different levels of details or of abstraction of the map and (3) integrated web-based blog for collecting community feedback. NaviCell can be easily used by experts in the field of molecular biology for studying molecular entities of interest in the context of signaling pathways and crosstalk between pathways within a global signaling network. NaviCell allows both exploration of detailed molecular mechanisms represented on the map and a more abstract view of the map up to a top-level modular representation. NaviCell greatly facilitates curation, maintenance and updating the comprehensive maps of molecular interactions in an interactive and user-friendly fashion due to an imbedded blogging system. NaviCell provides user-friendly exploration of large-scale maps of molecular interactions, thanks to Google Maps and WordPress interfaces, with which many users are already familiar. Semantic zooming which is used for navigating geographical maps is adopted for molecular maps in NaviCell, making any level of visualization readable. In addition, NaviCell provides a framework for community-based curation of maps.

Parallel Exploration of Interaction Space by BioID and Affinity Purification Coupled to Mass Spectrometry.

PubMed

Hesketh, Geoffrey G; Youn, Ji-Young; Samavarchi-Tehrani, Payman; Raught, Brian; Gingras, Anne-Claude

2017-01-01

Complete understanding of cellular function requires knowledge of the composition and dynamics of protein interaction networks, the importance of which spans all molecular cell biology fields. Mass spectrometry-based proteomics approaches are instrumental in this process, with affinity purification coupled to mass spectrometry (AP-MS) now widely used for defining interaction landscapes. Traditional AP-MS methods are well suited to providing information regarding the temporal aspects of soluble protein-protein interactions, but the requirement to maintain protein-protein interactions during cell lysis and AP means that both weak-affinity interactions and spatial information is lost. A more recently developed method called BioID employs the expression of bait proteins fused to a nonspecific biotin ligase, BirA*, that induces in vivo biotinylation of proximal proteins. Coupling this method to biotin affinity enrichment and mass spectrometry negates many of the solubility and interaction strength issues inherent in traditional AP-MS methods, and provides unparalleled spatial context for protein interactions. Here we describe the parallel implementation of both BioID and FLAG AP-MS allowing simultaneous exploration of both spatial and temporal aspects of protein interaction networks.

Ambidextrous Leadership and Employees' Self-reported Innovative Performance: The Role of Exploration and Exploitation Behaviors

ERIC Educational Resources Information Center

Zacher, Hannes; Robinson, Alecia J.; Rosing, Kathrin

2016-01-01

The ambidexterity theory of leadership for innovation proposes that leaders' opening and closing behaviors positively predict employees' exploration and exploitation behaviors, respectively. The interaction of exploration and exploitation behaviors, in turn, is assumed to influence employee innovative performance, such that innovative performance…

Interactive Visualization of Dependencies

ERIC Educational Resources Information Center

Moreno, Camilo Arango; Bischof, Walter F.; Hoover, H. James

2012-01-01

We present an interactive tool for browsing course requisites as a case study of dependency visualization. This tool uses multiple interactive visualizations to allow the user to explore the dependencies between courses. A usability study revealed that the proposed browser provides significant advantages over traditional methods, in terms of…

Semantic Interaction for Sensemaking: Inferring Analytical Reasoning for Model Steering.

PubMed

Endert, A; Fiaux, P; North, C

2012-12-01

Visual analytic tools aim to support the cognitively demanding task of sensemaking. Their success often depends on the ability to leverage capabilities of mathematical models, visualization, and human intuition through flexible, usable, and expressive interactions. Spatially clustering data is one effective metaphor for users to explore similarity and relationships between information, adjusting the weighting of dimensions or characteristics of the dataset to observe the change in the spatial layout. Semantic interaction is an approach to user interaction in such spatializations that couples these parametric modifications of the clustering model with users' analytic operations on the data (e.g., direct document movement in the spatialization, highlighting text, search, etc.). In this paper, we present results of a user study exploring the ability of semantic interaction in a visual analytic prototype, ForceSPIRE, to support sensemaking. We found that semantic interaction captures the analytical reasoning of the user through keyword weighting, and aids the user in co-creating a spatialization based on the user's reasoning and intuition.

Isotopic patterns in caps and stipes in sporocarps reveal patterns of organic nitrogen use by ectomycorrhizal fungi

NASA Astrophysics Data System (ADS)

Hobbie, Erik; Ouimette, Andrew; Chen, Janet

2016-04-01

Current ecosystem models use inorganic nitrogen as the currency of nitrogen acquisition by plants. However, many trees may gain access to otherwise unavailable soil resources, such as soil organic nitrogen, through their symbioses with ectomycorrhizal fungi, and this pathway of nitrogen acquisition may therefore be important in understanding plant responses to environmental change. Different functional groups of ectomycorrhizal fungi vary in their ability to enzymatically access protein and other soil resources. Such fungal parameters as hyphal hydrophobicity, the presence of rhizomorphs (long-distance transport structures), and exploration strategies (e.g., short-distance versus long-distance, mat formation) correspond with how fungi interact with and explore the environment, and the proportions of different exploration types present will shift along environmental gradients such as nitrogen availability. Isotopic differences between caps and stipes may provide a means to test for organic nitrogen use, since caps and stipes differ in δ13C and δ15N as a result of variable proportions of protein and other classes of compounds, and protein should differ isotopically among de novo synthesis, litter sources, and soil sources. Here, we propose that (1) isotopic differences between caps and stipes could be related to organic nitrogen uptake and to the δ13C and δ15N values of different pools of soil-derived or de novo-synthesized amino acids; (2) these isotopic differences will reflect greater acquisition of soil-derived organic nitrogen by exploration types of greater enzymatic capabilities to degrade recalcitrant nitrogen forms, specifically long-distance, medium-distance fringe, and medium-distance mat exploration types. To test these hypotheses, we use a dataset of isotopic values, %N, and %C in 208 cap/stipe samples collected from Oregon, western USA. δ13C differences in caps and stipes in a multiple regression model had an adjusted r2 of 0.292 (p < 0.0001), and were explained best by exploration type (45% of explained variance), the interaction of exploration type and %Ncap-stipe (20%), the interaction of exploration type and %Ncap/stipe (22%), %Ccap-stipe (8%), and %Ncap-stipe (5%). δ15N differences between caps and stipes in a multiple regression model had an adjusted r2 of 0.486 (p < 0.0001), and were explained best by exploration type (47% of explained variance), the interaction of exploration type and %Ncap-stipe (26%), the interaction of exploration type and %Ncap/stipe (14%), %Ncap/stipe (11%),and %Ccap-stipe (2%). We argue that these differences in the 13C and 15N enrichment of caps relative to stipes reflect not only shifts in the proportions of protein and carbohydrates, but also differences in the extent of fluxes and the δ13C and δ15N signatures of soil- and litter-derived organic nitrogen taken up by these fungi. We also propose equations to quantify this uptake. Organic nitrogen from litter (lower δ13C and δ15N) may be incorporated by medium-distance mat, short-distance, and contact exploration types of ectomycorrhizal fungi, whereas long-distance and medium-distance fringe exploration types appeared to incorporate deeper soil organic nitrogen.

Can We Become Friends? Students' Cross-Racial Interaction in Post-Apartheid South African Higher Education

ERIC Educational Resources Information Center

Wertheim, Samantha Shapses

2014-01-01

This article investigates and documents how undergraduate students in South Africa make meaning of cross-racial interaction on the college campus in the post-apartheid era. Additionally, it explores how students perceive that interactions with diverse peers have shifted since apartheid, and how these interactions are indicative of the larger…

Effects of Ignoring Item Interaction on Item Parameter Estimation and Detection of Interacting Items

ERIC Educational Resources Information Center

Chen, Cheng-Te; Wang, Wen-Chung

2007-01-01

This study explores the effects of ignoring item interaction on item parameter estimation and the efficiency of using the local dependence index Q[subscript 3] and the SAS NLMIXED procedure to detect item interaction under the three-parameter logistic model and the generalized partial credit model. Through simulations, it was found that ignoring…

Daily Family Interactions among Young Adults in the United States from Latin American, Filipino, East Asian, and European Backgrounds

ERIC Educational Resources Information Center

Fuligni, Andrew; Masten, Carrie L.

2010-01-01

In contrast to the abundant research on family relationships during adolescence, the nature of family interactions during young adulthood remains comparatively unexamined. The current study explored ethnic differences in young adults' interactions with parents and siblings, the role of other activities in young adults' family interactions, and the…

Human-Computer Interaction and Sociological Insight: A Theoretical Examination and Experiment in Building Affinity in Small Groups

ERIC Educational Resources Information Center

Oren, Michael Anthony

2011-01-01

The juxtaposition of classic sociological theory and the, relatively, young discipline of human-computer interaction (HCI) serves as a powerful mechanism for both exploring the theoretical impacts of technology on human interactions as well as the application of technological systems to moderate interactions. It is the intent of this dissertation…

Becoming "Spanish Learners": Identity and Interaction among Multilingual Children in a Spanish-English Dual Language Classroom

ERIC Educational Resources Information Center

Martínez, Ramón Antonio; Durán, Leah; Hikida, Michiko

2017-01-01

This article explores the interactional co-construction of identities among two first-grade students learning Spanish as a third language in a Spanish-English dual language classroom. Drawing on ethnographic and interactional data, the article focuses on a single interaction between these two "Spanish learners" and two of their…

They Work Together to Roar: Kindergartners' Understanding of an Interactive Causal Task

ERIC Educational Resources Information Center

Solis, S. Lynneth; Grotzer, Tina A.

2016-01-01

The aim of this study was to investigate kindergartners' exploration of interactive causality during their play with a pair of toy sound blocks. Interactive causality refers to a type of causal pattern in which two entities interact to produce a causal force, as in particle attraction and symbiotic relationships. Despite being prevalent in nature,…

Mapping Control and Affiliation in Teacher-Student Interaction with State Space Grids

ERIC Educational Resources Information Center

Mainhard, M. Tim; Pennings, Helena J. M.; Wubbels, Theo; Brekelmans, Mieke

2012-01-01

This paper explores how State Space Grids (SSG), a dynamic systems research method, can be used to map teacher-student interactions from moment-to-moment and thereby to incorporate temporal aspects of interaction. Interactions in two secondary school classrooms are described in terms of level of interpersonal control and affiliation, and of…

Exploring the Interaction between TSC2, PTEN, and the NMDA Receptor in Animal Models of Tuberous Sclerosis

DTIC Science & Technology

2014-09-01

Sunnen CN, Crowell B, Lee GH, Anderson AE, and D’Arcangelo G. Examination of the Role of Pten in Ionotropic Glutamate Receptor Expression. National...PTEN, and the NMDA Receptor in Animal Models of Tuberous Sclerosis PRINCIPAL INVESTIGATOR: D’Arcangelo, Gabriella CONTRACTING...June 2014 4. TITLE AND SUBTITLE Exploring the Interaction between TSC2, PTEN, and the NMDA Receptor in Animal Models of Tuberous Sclerosis 5a

Peer-to-Peer Human-Robot Interaction for Space Exploration

NASA Technical Reports Server (NTRS)

Fong, Terrence; Nourbakhsh, Illah

2004-01-01

NASA has embarked on a long-term program to develop human-robot systems for sustained, affordable space exploration. To support this mission, we are working to improve human-robot interaction and performance on planetary surfaces. Rather than building robots that function as glorified tools, our focus is to enable humans and robots to work as partners and peers. In this paper. we describe our approach, which includes contextual dialogue, cognitive modeling, and metrics-based field testing.

Exploring Plant Co-Expression and Gene-Gene Interactions with CORNET 3.0.

PubMed

Van Bel, Michiel; Coppens, Frederik

2017-01-01

Selecting and filtering a reference expression and interaction dataset when studying specific pathways and regulatory interactions can be a very time-consuming and error-prone task. In order to reduce the duplicated efforts required to amass such datasets, we have created the CORNET (CORrelation NETworks) platform which allows for easy access to a wide variety of data types: coexpression data, protein-protein interactions, regulatory interactions, and functional annotations. The CORNET platform outputs its results in either text format or through the Cytoscape framework, which is automatically launched by the CORNET website.CORNET 3.0 is the third iteration of the web platform designed for the user exploration of the coexpression space of plant genomes, with a focus on the model species Arabidopsis thaliana. Here we describe the platform: the tools, data, and best practices when using the platform. We indicate how the platform can be used to infer networks from a set of input genes, such as upregulated genes from an expression experiment. By exploring the network, new target and regulator genes can be discovered, allowing for follow-up experiments and more in-depth study. We also indicate how to avoid common pitfalls when evaluating the networks and how to avoid over interpretation of the results.All CORNET versions are available at http://bioinformatics.psb.ugent.be/cornet/ .

SIGI: An Interactive Aid to Career Decision Making.

ERIC Educational Resources Information Center

Katz, Martin R.

1980-01-01

The System of Interactive Guidance and Information (SIGI) helps students make informed and rational career decisions. Interacting with a computer, students examine values, identify and explore options, gain and interpret relevant information, master strategies for decision making, and formulate plans of action. Extensively field-tested, SIGI has…

The Role of Collegial Interaction in Continuing Professional Development

ERIC Educational Resources Information Center

Gagliardi, Anna R.; Wright, Frances C.; Anderson, Michael A. B.; Davis, Dave

2007-01-01

Introduction: Many physicians seek information from colleagues over other sources, highlighting the important role of interaction in continuing professional development (CPD). To guide the development of CPD opportunities, this study explored the nature of cancer-related questions faced by general surgeons, and how interaction with colleagues…

Talking with Abuelo: Performing Authenticity in a Multicultural, Multisited Family

ERIC Educational Resources Information Center

Vidal, Mónica

2015-01-01

Taking an interactional sociolinguistic approach, this study explores how multicultural and multilingual siblings interact with their Spanish grandfather and how, through the use of styling and stylization in these interactions, they negotiate and construct multicultural family identities. Using Tannen's power and solidarity framework, I analyze…

Improving Second Language Speaking Proficiency via Interactional Feedback

ERIC Educational Resources Information Center

Swanson, Peter B.; Schlig, Carmen

2010-01-01

Researchers have suggested that interactional feedback is associated with foreign/second language learning because it prompts learners to notice foreign/second language forms. Using Vygotsky's zone of proximal development and Long's interaction hypothesis as conceptual frameworks, this study explores the use of systematic explicit feedback to…

"Barter", "Deals", "Bribes" and "Threats": Exploring Sibling Interactions

ERIC Educational Resources Information Center

McIntosh, Ian; Punch, Samantha

2009-01-01

This article investigates forms of strategic interaction between siblings during childhood. The authors argue that these interactions, characterized by notions of reciprocity, equivalence and constructions of fairness, are worked out in relation to responsibility, power, knowledge and sibling status. Birth order and age are not experienced as…

Using Interactive Graphics to Teach Multivariate Data Analysis to Psychology Students

ERIC Educational Resources Information Center

Valero-Mora, Pedro M.; Ledesma, Ruben D.

2011-01-01

This paper discusses the use of interactive graphics to teach multivariate data analysis to Psychology students. Three techniques are explored through separate activities: parallel coordinates/boxplots; principal components/exploratory factor analysis; and cluster analysis. With interactive graphics, students may perform important parts of the…

MaGnET: Malaria Genome Exploration Tool

PubMed Central

Sharman, Joanna L.; Gerloff, Dietlind L.

2013-01-01

Summary: The Malaria Genome Exploration Tool (MaGnET) is a software tool enabling intuitive ‘exploration-style’ visualization of functional genomics data relating to the malaria parasite, Plasmodium falciparum. MaGnET provides innovative integrated graphic displays for different datasets, including genomic location of genes, mRNA expression data, protein–protein interactions and more. Any selection of genes to explore made by the user is easily carried over between the different viewers for different datasets, and can be changed interactively at any point (without returning to a search). Availability and Implementation: Free online use (Java Web Start) or download (Java application archive and MySQL database; requires local MySQL installation) at http://malariagenomeexplorer.org Contact: joanna.sharman@ed.ac.uk or dgerloff@ffame.org Supplementary information: Supplementary data are available at Bioinformatics online. PMID:23894142

Pavlovian Conditioning of Social Exploration in Adult Female Rats.

PubMed

Sunsay, Ceyhun

2018-06-02

Social conditionaed place preference (SCPP) studies show that the reward value of social interaction is amenable to the laws of associative learning, such that it becomes associated with the physical properties of the context. However, social interaction can be initiated and maintained by a variety of motivations, such as the exploration of a novel conspecific, aggression, mutual grooming and mating-like actions. In order to study whether social exploration is rewarding, we used a conventional Pavlovian conditioning procedure in which access to a restrained same-sex rat served as a reward. Three dependent variables in two experiments showed that the reward value of social exploration becomes conditioned to a transient cue, and it is also subject to extinction and spontaneous recovery. The results may help to elucidate the mixed results obtained with SCPP procedures. Copyright © 2018. Published by Elsevier B.V.

The Dynamic Reactance Interaction - How Vested Interests Affect People's Experience, Behavior, and Cognition in Social Interactions.

PubMed

Steindl, Christina; Jonas, Eva

2015-01-01

In social interactions, individuals may sometimes pursue their own interests at the expense of their interaction partner. Such self-interested behaviors impose a threat to the interaction partner's freedom to act. The current article investigates this threat in the context of interdependence and reactance theory. We explore how vested interests influence reactance process stages of an advisor-client interaction. We aim to explore the interactional process that evolves. In two studies, participants took the perspective of a doctor (advisor) or a patient (client). In both studies we incorporated a vested interest. In Study 1 (N = 82) we found that in response to a vested interest of their interaction partner, patients indicated a stronger experience of reactance, more aggressive behavioral intentions, and more biased cognitions than doctors. A serial multiple mediation revealed that a vested interest engendered mistrust toward the interaction partner and this mistrust led to an emerging reactance process. Study 2 (N = 207) further demonstrated that doctors expressed their reactance in a subtle way: they revealed a classic confirmation bias when searching for additional information on their preliminary decision preference, indicating stronger defense motivation. We discuss how these findings can help us to understand how social interactions develop dynamically.

The Dynamic Reactance Interaction – How Vested Interests Affect People’s Experience, Behavior, and Cognition in Social Interactions

PubMed Central

Steindl, Christina; Jonas, Eva

2015-01-01

In social interactions, individuals may sometimes pursue their own interests at the expense of their interaction partner. Such self-interested behaviors impose a threat to the interaction partner’s freedom to act. The current article investigates this threat in the context of interdependence and reactance theory. We explore how vested interests influence reactance process stages of an advisor–client interaction. We aim to explore the interactional process that evolves. In two studies, participants took the perspective of a doctor (advisor) or a patient (client). In both studies we incorporated a vested interest. In Study 1 (N = 82) we found that in response to a vested interest of their interaction partner, patients indicated a stronger experience of reactance, more aggressive behavioral intentions, and more biased cognitions than doctors. A serial multiple mediation revealed that a vested interest engendered mistrust toward the interaction partner and this mistrust led to an emerging reactance process. Study 2 (N = 207) further demonstrated that doctors expressed their reactance in a subtle way: they revealed a classic confirmation bias when searching for additional information on their preliminary decision preference, indicating stronger defense motivation. We discuss how these findings can help us to understand how social interactions develop dynamically. PMID:26640444

"My love-hate relationship": Ethical issues associated with nurses' interactions with industry.

PubMed

Grundy, Quinn

2014-08-01

Ethical issues associated with nurses' interactions with industry have implications for the safety, quality, and cost of healthcare. To date, little work has explored nurse-industry interactions and their associated ethical issues empirically. A phenomenological study was conducted to explore registered nurses' interactions with industry in clinical practice. Five registered nurses working in direct patient care were recruited and individual, in-depth interviews were conducted. The University's Committee on Human Research approved the study. Nurses frequently interacted with industry in their practice and felt ambivalent about these interactions. Nurses described systemic cuts to multiple "goods" central to nursing practice, including patient support, but paradoxically relied on industry resources to deliver these "goods." They relied on a particular conception of trust to navigate these interactions but were left to do so individually on the basis of their experience. Conflicts of interest arose as a result of multiple competing interests, and were frequently mediated through nurses' superiors. Nursing as a profession requires a guiding narrative to aid nurses in interpreting and navigating interactions with industry. A conception of trust that incorporates both the work of caring and attention to social justice could form the basis of these interactions, but would require that nursing take a much more critical stance toward marketing interactions. © The Author(s) 2013.

Biophysical interactions with model lipid membranes: applications in drug discovery and drug delivery

PubMed Central

Peetla, Chiranjeevi; Stine, Andrew; Labhasetwar, Vinod

2009-01-01

The transport of drugs or drug delivery systems across the cell membrane is a complex biological process, often difficult to understand because of its dynamic nature. In this regard, model lipid membranes, which mimic many aspects of cell-membrane lipids, have been very useful in helping investigators to discern the roles of lipids in cellular interactions. One can use drug-lipid interactions to predict pharmacokinetic properties of drugs, such as their transport, biodistribution, accumulation, and hence efficacy. These interactions can also be used to study the mechanisms of transport, based on the structure and hydrophilicity/hydrophobicity of drug molecules. In recent years, model lipid membranes have also been explored to understand their mechanisms of interactions with peptides, polymers, and nanocarriers. These interaction studies can be used to design and develop efficient drug delivery systems. Changes in the lipid composition of cells and tissue in certain disease conditions may alter biophysical interactions, which could be explored to develop target-specific drugs and drug delivery systems. In this review, we discuss different model membranes, drug-lipid interactions and their significance, studies of model membrane interactions with nanocarriers, and how biophysical interaction studies with lipid model membranes could play an important role in drug discovery and drug delivery. PMID:19432455

iVFTs - immersive virtual field trips for interactive learning about Earth's environment.

NASA Astrophysics Data System (ADS)

Bruce, G.; Anbar, A. D.; Semken, S. C.; Summons, R. E.; Oliver, C.; Buxner, S.

2014-12-01

Innovations in immersive interactive technologies are changing the way students explore Earth and its environment. State-of-the-art hardware has given developers the tools needed to capture high-resolution spherical content, 360° panoramic video, giga-pixel imagery, and unique viewpoints via unmanned aerial vehicles as they explore remote and physically challenging regions of our planet. Advanced software enables integration of these data into seamless, dynamic, immersive, interactive, content-rich, and learner-driven virtual field explorations, experienced online via HTML5. These surpass conventional online exercises that use 2-D static imagery and enable the student to engage in these virtual environments that are more like games than like lectures. Grounded in the active learning of exploration, inquiry, and application of knowledge as it is acquired, users interact non-linearly in conjunction with an intelligent tutoring system (ITS). The integration of this system allows the educational experience to be adapted to each individual student as they interact within the program. Such explorations, which we term "immersive virtual field trips" (iVFTs), are being integrated into cyber-learning allowing science teachers to take students to scientifically significant but inaccessible environments. Our team and collaborators are producing a diverse suite of freely accessible, iVFTs to teach key concepts in geology, astrobiology, ecology, and anthropology. Topics include Early Life, Biodiversity, Impact craters, Photosynthesis, Geologic Time, Stratigraphy, Tectonics, Volcanism, Surface Processes, The Rise of Oxygen, Origin of Water, Early Civilizations, Early Multicellular Organisms, and Bioarcheology. These diverse topics allow students to experience field sites all over the world, including, Grand Canyon (USA), Flinders Ranges (Australia), Shark Bay (Australia), Rainforests (Panama), Teotihuacan (Mexico), Upheaval Dome (USA), Pilbara (Australia), Mid-Atlantic Ridge (Iceland), and Mauna Kea (Hawaii). iVFTs are being beta-tested and used at ASU in several large-enrollment courses to assess its usability and effectiveness in meeting specific learning objectives. We invite geoscience educators to partake of this resource and find new applications to their own teaching.

A National Reassessment: Exploring Variables that Predispose People with Disabilities to Vocational Rehabilitation Acceptance

ERIC Educational Resources Information Center

Wilson, Keith B.; Gines, Jason E.

2009-01-01

Vocational rehabilitation (VR) acceptance has been explored by many research teams over the last 30 years. However, none of the prior studies explored the multitude of demographic variables that may influence VR acceptance and the possible interactions of those variables with VR acceptance. Extrapolating demographic variables from the national…

Spatial Exploration and Changes in Infant-Mother Dyads around Transitions in Infant Locomotion

ERIC Educational Resources Information Center

Thurman, Sabrina L.; Corbetta, Daniela

2017-01-01

Infants' motor skill development triggers changes in parent-infant interactions, exploration, and play behaviors, particularly during periods of locomotor transitions. We investigated how these transitions reorganized infants' and mothers' explorations of spatial layouts. Thirteen infants and their mothers were followed biweekly from the age of 6…

Using Dynamic Geometry Software to Explore Eigenvectors: The Emergence of Dynamic-Synthetic-Geometric Thinking

ERIC Educational Resources Information Center

Gol Tabaghi, Shiva; Sinclair, Nathalie

2013-01-01

This article analyses students' thinking as they interacted with a dynamic geometric sketch designed to explore eigenvectors and eigenvalues. We draw on the theory of instrumental genesis and, in particular, attend to the different dragging modalities used by the students throughout their explorations. Given the kinaesthetic and dynamic…

Interact for What? The Relationship between Interpersonal Interaction Based on Motivation and Educational Outcomes among Students in Manufacturing Programs at Two-Year Technical Colleges

ERIC Educational Resources Information Center

Chan, Hsun-yu; Wang, Xueli

2016-01-01

Objective: This study explored the relationship between different types of interpersonal interaction, characterized by their underlying motivations, and educational outcomes among students in manufacturing programs at two-year colleges. While there exist several ways to classify interaction, motivation as an inherent attribute that fuels behaviors…

You and Me: The Structural Basis for the Interaction of People with Severe and Profound Intellectual Disability and Others

ERIC Educational Resources Information Center

Griffiths, Colin; Smith, Martine

2017-01-01

Interaction between two people may be construed as a continuous process of perception and action within the dyad. A theoretical framework is proposed in this article that explains the concepts and processes which comprise the interaction process. The article explores the transactional nature of interaction, through analysis of narrative data from…

Interactive Alignment of Multisyllabic Stress Patterns in a Second Language Classroom

ERIC Educational Resources Information Center

Trofimovich, Pavel; McDonough, Kim; Foote, Jennifer A.

2014-01-01

The current study explored the occurrence of stress pattern alignment during peer interaction in a second language (L2) classroom. Interactive alignment is a sociocognitive phenomenon in which interlocutors reuse each other's expressions, structures, and pronunciation patterns during conversation. Students (N = 41) enrolled in a…

Interactive Video: A Cross Curriculum Computer Project.

ERIC Educational Resources Information Center

Grimm, Floyd M., III; And Others

Responding to the rapid development and often prohibitive costs of new classroom instruction technology, a group of interested faculty at Harford Community College (HCC), in Maryland, formed three Interactive Video (IV) Teams to explore the possibilities of using existing computer hardware and software at the college for interactive video…

Pharmacist-Patient Interaction and Patient Expectations

ERIC Educational Resources Information Center

DeSimone, Edward M.; And Others

1977-01-01

The nature of the professional interaction between the pharmacist and the patient was explored, with data collected from 3,743 questions asked of 16 pharmacists during an 8-week period. Factors that might affect the nature of the pharmacist-patient interaction are identified along with a cognitive-based profile of patient wants. (LBH)

Dyadic Interracial Interactions: A Meta-Analysis

ERIC Educational Resources Information Center

Toosi, Negin R.; Babbitt, Laura G.; Ambady, Nalini; Sommers, Samuel R.

2012-01-01

This meta-analysis examined over 40 years of research on interracial interactions by exploring 4 types of outcomes: explicit attitudes toward interaction partners, participants' self-reports of their own emotional state, nonverbal or observed behavior, and objective measures of performance. Data were collected from 108 samples (N = 12,463)…

Challenges of Developing Communicative Interaction in Individuals with Congenital Profound Intellectual and Multiple Disabilities

ERIC Educational Resources Information Center

Blain-Moraes, Stefanie; Chau, Tom

2012-01-01

Background: Physiological responses have been used in individuals with acquired disability to enable communicative interaction without motor movement. This study explored four autonomic nervous system (ANS) signals--electrodermal activity, skin temperature, cardiac patterns and respiratory patterns--to enable interaction with individuals born with…

Interactions among Social Welfare Programs.

ERIC Educational Resources Information Center

Lewis, Gordon H.; Morrison, Richard J.

1990-01-01

This paper explores interactions between social welfare programs and associated supportive taxation programs. Focus was on the effect of one program on another, effects of one program on a set of other programs, effects of tax and benefit reduction rates, and effects of interacting programs on the governments that create/maintain them. (TJH)

Negative Interpersonal Interactions in Student Training Settings

ERIC Educational Resources Information Center

Ferris, Patricia A.; Kline, Theresa J. B.

2009-01-01

Studies demonstrate that negative interpersonal interaction(s) (NII) such as bullying are frequent and harmful to individuals in workplace and higher education student settings. Nevertheless, it is unclear whether the degree of perceived severity of NII varies by the status of the actor. The present study explored the moderating effect of actor…

Exploration of Problematic Internet Use and Social Interaction Anxiety among Turkish Pre-Service Teachers

ERIC Educational Resources Information Center

Cuhadar, Cem

2012-01-01

The current study investigated the relationship between problematic Internet use and social interaction anxiety among pre-service teachers. Participants were 1235 students attending teacher training programs at a Turkish state university. The "Problematic Internet Use Scale" and "Social Interaction Anxiety Scale" were used to…

The Factors Influencing Young Children's Social Interaction in Technology Integration

ERIC Educational Resources Information Center

Lim, Eun Mee

2015-01-01

When technology integration is accomplished successfully in early childhood education settings, children tend to interact more with one another and exchange information related to computer tasks as well as the overall classroom on-going curriculum themes. Therefore, to explore how young children are interacting in computer areas when using…

Learning SQL Programming with Interactive Tools: From Integration to Personalization

ERIC Educational Resources Information Center

Brusilovsky, Pete; Sosnovsky, Sergey; Yudelson, Michael V.; Lee, Danielle H.; Zadorozhny, Vladimir; Zhou, Xin

2010-01-01

Rich, interactive eLearning tools receive a lot of attention nowadays from both practitioners and researchers. However, broader dissemination of these tools is hindered by the technical difficulties of their integration into existing platforms. This article explores the technical and conceptual problems of using several interactive educational…

Practice and Personhood in Professional Interaction: Social Identities and Information Needs.

ERIC Educational Resources Information Center

Mokros, Hartmut B.; And Others

1995-01-01

Explores the human aspect of information retrieval by examining the behavior and pronoun use of librarians in the course of communicating with patrons during online computer search interactions. Compares two studies on the conduct of librarians as intermediaries in naturally occurring online computer search interactions. (JMV)

Friends in Passing: Social Interaction at an Adult Day Care Center.

ERIC Educational Resources Information Center

Williams, Barbara; Roberts, Pamela

1995-01-01

Participant observation study explored social interactions and friendships among cognitively impaired adult day-care participants. Found clients engage in a variety of social interactions and friendships, enabling them to maintain a sense of self and to adjust to group norms. Discussed general socializing, enduring friendships, helping…

Exploring the Contribution of a Content-Infused Interactive Whiteboard for School Readiness

ERIC Educational Resources Information Center

McManis, Lilla D.; Gunnewig, Susan B.; McManis, Mark H.

2010-01-01

This exploratory study examined the relationship between use of an interactive (touchscreen) whiteboard and development of school readiness skills. Over one school year, public school regular education prekindergarten classrooms used an interactive whiteboard with preloaded literacy and math activities. The children were low-income and English…

Perceived Density, Social Interaction and Morale in New South Wales Rural Communities

ERIC Educational Resources Information Center

Argent, Neil

2008-01-01

This paper explores the relationships between population density, social interaction patterns, and morale in rural communities. It tests two apparently competing hypotheses concerning rural population density, social interaction patterns and overall levels of morale: one, that low (and rapidly declining) rural densities lead to feelings of…

Positioning and Latinas/os: A Study of Small-Group Interactions in Mathematics

ERIC Educational Resources Information Center

Lopez Leiva, Carlos Alfonso

2011-01-01

This study explores social interaction and mathematics performance, especially regarding how bilingual Latino/a students' positioning and participation evolved as they interacted with others in mathematics problem solving. Historically, Latinas/os have faced segregation in different ways that affect the quality of their social interactions…

Psychological Development and Females' Sport Participation: An Interactional Perspective.

ERIC Educational Resources Information Center

Weiss, Maureen R.; Glenn, Susan D.

1992-01-01

This paper examines the writings of Dorothy Harris and other authors, from a psychosocial perspective of sport involvement. It explores ways self-perceptions, social factors, and cognitive and biological maturity interact to explain females' physical activity participation; it proposes a heuristic model to represent an interactional approach. (SM)

Person, Situational, and Interactional Influences on Assertive Behavior.

ERIC Educational Resources Information Center

Kirschner, Stuart M.; Galassi, John P.

1983-01-01

Explored the validity of the College Self-Expression Scale (CSES) for 144 students in the context of three alternative models of behavior--personism, situationalism, and interactionalism. Results supported the concurrent validity of the CSES and the role of both person and situational, but not interactional, influences on assertion. (WAS)

Improving the EFL Learners' Speaking Ability through Interactive Storytelling

ERIC Educational Resources Information Center

Marzuki; Prayogo, Johannes Ananto; Wahyudi, Arwijati

2016-01-01

This present research was aimed to improve the EFL learners' speaking ability and their classroom activities through the implementation of Interactive Storytelling Strategy. Therefore, this study was directed to explore the beneficial of Interactive Storytelling that closely related to the EFL learners' everyday activities at their home and…

Front-Line Educators: The Impact of Classified Staff Interactions on the Student Experience

ERIC Educational Resources Information Center

Schmitt, Mary Ann; Duggan, Molly H.; Williams, Mitchell R.; McMillan, Judy B.

2015-01-01

This multiple case study explored classified staff interactions with students as a strategy for increasing success. Interviews, observations, and focus groups examined interactions from the staff perspective. Findings indicate staff members enhance the educational process by providing a human connection, offering practical strategies for success,…

Constructing Interpretative Views of Learners' Interaction Behavior in an Open Learner Model

ERIC Educational Resources Information Center

Papanikolaou, Kyparisia A.

2015-01-01

In this paper, we discuss how externalizing learners' interaction behavior may support learners' explorations in an adaptive educational hypermedia environment that provides activity-oriented content. In particular, we propose a model for producing interpretative views of learners' interaction behavior and we further apply this model to…

Iterative Exploration, Design and Evaluation of Support for Query Reformulation in Interactive Information Retrieval.

ERIC Educational Resources Information Center

Belkin, N. J.; Cool, C.; Kelly, D.; Lin, S. -J.; Park, S. Y.; Perez-Carballo, J.; Sikora, C.

2001-01-01

Reports on the progressive investigation of techniques for supporting interactive query reformulation in the TREC (Text Retrieval Conference) Interactive Track. Highlights include methods of term suggestion; interface design to support different system functionalities; an overview of each year's TREC investigation; and relevance to the development…

Promoting Positive Interactions between Mothers and Their At-Risk Young Children

ERIC Educational Resources Information Center

Stephenson, Jennifer; Martin, Andrew J.; Linfoot, Ken W.

2005-01-01

This study explores the impact of an exploratory, minimalist intervention based on the principles of social communication training that aimed at promoting positive interactions between mother and child and increasing child initiations in mother-child communication. Encouraging data indicated a shift towards a more positive interaction style…

The Human-Computer Interaction of Cross-Cultural Gaming Strategy

ERIC Educational Resources Information Center

Chakraborty, Joyram; Norcio, Anthony F.; Van Der Veer, Jacob J.; Andre, Charles F.; Miller, Zachary; Regelsberger, Alexander

2015-01-01

This article explores the cultural dimensions of the human-computer interaction that underlies gaming strategies. The article is a desktop study of existing literature and is organized into five sections. The first examines the cultural aspects of knowledge processing. The social constructs technology interaction is discussed. Following this, the…

Revisiting the continuum hypothesis: toward an in-depth exploration of executive functions in korsakoff syndrome.

PubMed

Brion, Mélanie; Pitel, Anne-Lise; Beaunieux, Hélène; Maurage, Pierre

2014-01-01

Korsakoff syndrome (KS) is a neurological state mostly caused by alcohol-dependence and leading to disproportionate episodic memory deficits. KS patients present more severe anterograde amnesia than Alcohol-Dependent Subjects (ADS), which led to the continuum hypothesis postulating a progressive increase in brain and cognitive damages during the evolution from ADS to KS. This hypothesis has been extensively examined for memory but is still debated for other abilities, notably executive functions (EF). EF have up to now been explored by unspecific tasks in KS, and few studies explored their interactions with memory. Exploring EF in KS by specific tasks based on current EF models could thus renew the exploration of the continuum hypothesis. This paper will propose a research program aiming at: (1) clarifying the extent of executive dysfunctions in KS by tasks focusing on specific EF subcomponents; (2) determining the differential EF deficits in ADS and KS; (3) exploring EF-memory interactions in KS with innovative tasks. At the fundamental level, this exploration will test the continuum hypothesis beyond memory. At the clinical level, it will propose new rehabilitation tools focusing on the EF specifically impaired in KS.

Revisiting the Continuum Hypothesis: Toward an In-Depth Exploration of Executive Functions in Korsakoff Syndrome

PubMed Central

Brion, Mélanie; Pitel, Anne-Lise; Beaunieux, Hélène; Maurage, Pierre

2014-01-01

Korsakoff syndrome (KS) is a neurological state mostly caused by alcohol-dependence and leading to disproportionate episodic memory deficits. KS patients present more severe anterograde amnesia than Alcohol-Dependent Subjects (ADS), which led to the continuum hypothesis postulating a progressive increase in brain and cognitive damages during the evolution from ADS to KS. This hypothesis has been extensively examined for memory but is still debated for other abilities, notably executive functions (EF). EF have up to now been explored by unspecific tasks in KS, and few studies explored their interactions with memory. Exploring EF in KS by specific tasks based on current EF models could thus renew the exploration of the continuum hypothesis. This paper will propose a research program aiming at: (1) clarifying the extent of executive dysfunctions in KS by tasks focusing on specific EF subcomponents; (2) determining the differential EF deficits in ADS and KS; (3) exploring EF-memory interactions in KS with innovative tasks. At the fundamental level, this exploration will test the continuum hypothesis beyond memory. At the clinical level, it will propose new rehabilitation tools focusing on the EF specifically impaired in KS. PMID:25071526

An Interactive Visualization Framework to Support Exploration and Analysis of TBI/PTSD Clinical Data

DTIC Science & Technology

2017-05-01

techniques to overcome some of the challenges and complexities of the data . Our approach uses a novel adaptive window-based frequency sequence mining ...AWARD NUMBER: W81XWH-15-2-0016 TITLE: An Interactive Visualization Framework to Support Exploration and Analysis of TBI/PTSD Clinical Data ...Analysis of TBI/PTSD Clinical Data 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-15-2-0016 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Dr. Jesus Caban 5d

Observations on the Use of Manual Signs and Gestures in the Communicative Interactions between Native Americans and Spanish Explorers of North America: The Accounts of Bernal Diaz del Castillo and Alvar Nunez Cabeza de Vaca

ERIC Educational Resources Information Center

Bonvillian, John D.; Ingram, Vicky L.; McCleary, Brendan M.

2009-01-01

The accounts of two men who participated in several Spanish-led expeditions to the New World in the early 1500s document the frequent use of manual signs and gestures in the initial interactions between European explorers and the indigenous peoples of North America. Bernal Diaz del Castillo described the events that occurred during three…

Smart Drill-Down: A New Data Exploration Operator

PubMed Central

Joglekar, Manas; Garcia-Molina, Hector; Parameswaran, Aditya

2015-01-01

We present a data exploration system equipped with smart drill-down, a novel operator for interactively exploring a relational table to discover and summarize “interesting” groups of tuples. Each such group of tuples is represented by a rule. For instance, the rule (a, b, ★, 1000) tells us that there are a thousand tuples with value a in the first column and b in the second column (and any value in the third column). Smart drill-down presents an analyst with a list of rules that together describe interesting aspects of the table. The analyst can tailor the definition of interesting, and can interactively apply smart drill-down on an existing rule to explore that part of the table. In the demonstration, conference attendees will be able to use the data exploration system equipped with smart drill-down, and will be able to contrast smart drill-down to traditional drill-down, for various interestingness measures, and resource constraints. PMID:26844008

Ethanol and Caffeine Effects on Social Interaction and Recognition in Mice: Involvement of Adenosine A2A and A1 Receptors.

PubMed

López-Cruz, Laura; San-Miguel, Noemí; Bayarri, Pilar; Baqi, Younis; Müller, Christa E; Salamone, John D; Correa, Mercé

2016-01-01

Ethanol and caffeine are frequently consumed in combination and have opposite effects on the adenosine system: ethanol metabolism leads to an increase in adenosine levels, while caffeine is a non-selective adenosine A 1 /A 2A receptor antagonist. These receptors are highly expressed in striatum and olfactory tubercle, brain areas involved in exploration and social interaction in rodents. Ethanol modulates social interaction processes, but the role of adenosine in social behavior is still poorly understood. The present work was undertaken to study the impact of ethanol, caffeine and their combination on social behavior, and to explore the involvement of A 1 and A 2A receptors on those actions. Male CD1 mice were evaluated in a social interaction three-chamber paradigm, for preference of conspecific vs. object, and also for long-term recognition memory of familiar vs. novel conspecific. Ethanol showed a biphasic effect, with low doses (0.25 g/kg) increasing social contact and higher doses (1.0-1.5 g/kg) reducing social interaction. However, no dose changed social preference; mice always spent more time sniffing the conspecific than the object, independently of the ethanol dose. Ethanol, even at doses that did not change social exploration, produced amnestic effects on social recognition the following day. Caffeine reduced social contact (15.0-60.0 mg/kg), and even blocked social preference at higher doses (30.0-60.0 mg/kg). The A 1 antagonist Cyclopentyltheophylline (CPT; 3-9 mg/kg) did not modify social contact or preference on its own, and the A 2A antagonist MSX-3 (1.5-6 mg/kg) increased social interaction at all doses. Ethanol at intermediate doses (0.5-1.0 g/kg) was able to reverse the reduction in social exploration induced by caffeine (15.0-30.0 mg/kg). Although there was no interaction between ethanol and CPT or MSX-3 on social exploration in the first day, MSX-3 blocked the amnestic effects of ethanol observed on the following day. Thus, ethanol impairs the formation of social memories, and A 2A adenosine antagonists can prevent the amnestic effects of ethanol, so that animals can recognize familiar conspecifics. On the other hand, ethanol can counteract the social withdrawal induced by caffeine, a non-selective adenosine A 1 /A 2A receptor antagonist. These results show the complex set of interactions between ethanol and caffeine, some of which could be the result of the opposing effects they have in modulating the adenosine system.

New Paradigms for Human-Robotic Collaboration During Human Planetary Exploration

NASA Astrophysics Data System (ADS)

Parrish, J. C.; Beaty, D. W.; Bleacher, J. E.

2017-02-01

Human exploration missions to other planetary bodies offer new paradigms for collaboration (control, interaction) between humans and robots beyond the methods currently used to control robots from Earth and robots in Earth orbit.

WHAM!: a web-based visualization suite for user-defined analysis of metagenomic shotgun sequencing data.

PubMed

Devlin, Joseph C; Battaglia, Thomas; Blaser, Martin J; Ruggles, Kelly V

2018-06-25

Exploration of large data sets, such as shotgun metagenomic sequence or expression data, by biomedical experts and medical professionals remains as a major bottleneck in the scientific discovery process. Although tools for this purpose exist for 16S ribosomal RNA sequencing analysis, there is a growing but still insufficient number of user-friendly interactive visualization workflows for easy data exploration and figure generation. The development of such platforms for this purpose is necessary to accelerate and streamline microbiome laboratory research. We developed the Workflow Hub for Automated Metagenomic Exploration (WHAM!) as a web-based interactive tool capable of user-directed data visualization and statistical analysis of annotated shotgun metagenomic and metatranscriptomic data sets. WHAM! includes exploratory and hypothesis-based gene and taxa search modules for visualizing differences in microbial taxa and gene family expression across experimental groups, and for creating publication quality figures without the need for command line interface or in-house bioinformatics. WHAM! is an interactive and customizable tool for downstream metagenomic and metatranscriptomic analysis providing a user-friendly interface allowing for easy data exploration by microbiome and ecological experts to facilitate discovery in multi-dimensional and large-scale data sets.

Viewpoints: A New Computer Program for Interactive Exploration of Large Multivariate Space Science and Astrophysics Data.

NASA Astrophysics Data System (ADS)

Levit, Creon; Gazis, P.

2006-06-01

The graphics processing units (GPUs) built in to all professional desktop and laptop computers currently on the market are capable of transforming, filtering, and rendering hundreds of millions of points per second. We present a prototype open-source cross-platform (windows, linux, Apple OSX) application which leverages some of the power latent in the GPU to enable smooth interactive exploration and analysis of large high-dimensional data using a variety of classical and recent techniques. The targeted application area is the interactive analysis of complex, multivariate space science and astrophysics data sets, with dimensionalities that may surpass 100 and sample sizes that may exceed 10^6-10^8.

Golgi: Interactive Online Brain Mapping

PubMed Central

Brown, Ramsay A.; Swanson, Larry W.

2015-01-01

Golgi (http://www.usegolgi.com) is a prototype interactive brain map of the rat brain that helps researchers intuitively interact with neuroanatomy, connectomics, and cellular and chemical architecture. The flood of “-omic” data urges new ways to help researchers connect discrete findings to the larger context of the nervous system. Here we explore Golgi’s underlying reasoning and techniques and how our design decisions balance the constraints of building both a scientifically useful and usable tool. We demonstrate how Golgi can enhance connectomic literature searches with a case study investigating a thalamocortical circuit involving the Nucleus Accumbens and we explore Golgi’s potential and future directions for growth in systems neuroscience and connectomics. PMID:26635596

Fluxacademy: From Intermedia to Interactive Education.

ERIC Educational Resources Information Center

Saper, Craig

1992-01-01

Advocates a Fluxus-based experimental pedagogy which is suited for scholarship confronted with film and electronic media. Notes that the theory explored in Fluxacademy focuses specifically on the use of intermedia for interactive education. (RS)

The influence of arene-ring size on stacking interaction with canonical base pairs

NASA Astrophysics Data System (ADS)

Formánek, Martin; Burda, Jaroslav V.

2014-04-01

Stacking interactions between aromatic molecules (benzene, p-cymene, biphenyl, and di- and tetra-hydrogen anthracene) and G.C and A.T canonical Watson-Crick (WC) base pairs are explored. Two functionals with dispersion corrections: ω-B97XD and B3LYP-D3 are used. For a comparison also the MP2 and B3LYP-D3/PCM methods were used for the most stable p-cymene…WC geometries. It was found that the stacking interaction increases with the size of π-conjugation system. Its extent is in agreement with experimental finding on anticancer activity of Ru(II) piano-stool complexes where intercalation of these aromatic molecules should play an important role. The explored structures are considered as ternary system so that decomposition of the interaction energy to pairwise and non-additivity contributions is also examined.

The DIMA web resource--exploring the protein domain network.

PubMed

Pagel, Philipp; Oesterheld, Matthias; Stümpflen, Volker; Frishman, Dmitrij

2006-04-15

Conserved domains represent essential building blocks of most known proteins. Owing to their role as modular components carrying out specific functions they form a network based both on functional relations and direct physical interactions. We have previously shown that domain interaction networks provide substantially novel information with respect to networks built on full-length protein chains. In this work we present a comprehensive web resource for exploring the Domain Interaction MAp (DIMA), interactively. The tool aims at integration of multiple data sources and prediction techniques, two of which have been implemented so far: domain phylogenetic profiling and experimentally demonstrated domain contacts from known three-dimensional structures. A powerful yet simple user interface enables the user to compute, visualize, navigate and download domain networks based on specific search criteria. http://mips.gsf.de/genre/proj/dima

Preface - 'Biogeochemistry-ecosystem interaction on changing continental margins in the Anthropocene'

NASA Astrophysics Data System (ADS)

Liu, K.-K.; Emeis, Kay-Christian; Levin, Lisa A.; Naqvi, Wajih; Roman, Michael

2015-01-01

This special issue is a product of Workshop 1 of IMBIZO III held in Goa, India in January 2013 (Bundy et al., 2013). This IMBIZO (a Zulu word for gathering) has been organized by IMBER (Integrated Marine Biogeochemistry and Ecosystem Research) biannually since 2008. It employs a format of three concurrent but interacting workshops designed to synthesize information on topical research areas in marine science. Workshop 1 addressed the issue, "Biogeochemistry-ecosystem interaction in changing continental margins," which belongs to the purview of the Continental Margins Working Group (CMWG), co-sponsored by IMBER and LOICZ (Land-Ocean Interaction in the Coastal Zone). As a way to explore the emerging issues that concern the CMWG, the workshop had attracted 25 talks and 18 posters that explored the following topics: Human impacts on continental margins

Dancing in the thresholds: Exploring the interactive field

NASA Astrophysics Data System (ADS)

Rodriguez, Constance S.

This dissertation is an attempt to investigate the nature of the interactive field to deepen as well as broaden its scope as it applies to depth psychology and its praxis. With a phenomenological eye toward field dynamics from other paradigms, this exploration demonstrates an additional theoretical framework within the interactive field. It opens other possibilities creating a neither/nor position from which to contain our work with an alchemical/metaphorical position and allows for the liberation of the imaginal realm through which ``the Other'' may be of service, and in fact, may ask us to be in service to it. The literature review not only surveys the three primary schools in psychology-the psychoanalytical, the classical, and archetypal as the genesis of the interactive field, but also investigates shamanic realms as a backdrop from which to see field theory. Field theory is also explored in the world of quantum physics where the universal field is examined from paradigms situated in varied consciousness models. The somatic unconscious, an intrinsic part of the interactive field in mutual engagement with two or more persons, is also woven into the fabric of this study as an intersection between the universal field and the psychodynamic field. This study, as a psychological gnosis, initiates subtle body awareness from Eastern cosmologies from a depth perspective in the psychodynamics of the interactive field. Synchronistic encounters are integrated into field theory as a threshold where universal fields engage the somatic unconscious, initiating numinous and sometimes transformative change into one's life.

Two component Feebly Interacting Massive Particle (FIMP) dark matter

NASA Astrophysics Data System (ADS)

Pandey, Madhurima; Majumdar, Debasish; Prasad Modak, Kamakshya

2018-06-01

We explore the idea of an alternative candidate for particle dark matter namely Feebly Interacting Massive Particle (FIMP) in the framework of a two component singlet scalar model. Singlet scalar dark matter has already been demonstrated to be a viable candidate for WIMP (Weakly Interacting Massive Particle) dark matter in literature. In the FIMP scenario, dark matter particles are slowly produced via "thermal freeze-in" mechanism in the early Universe and are never abundant enough to reach thermal equilibrium or to undergo pair annihilation inside the Universe's plasma due to their extremely small couplings. We demonstrate that for smaller couplings too, required for freeze-in process, a two component scalar dark matter model considered here could well be a viable candidate for FIMP . In this scenario, the Standard Model of particle physics is extended by two gauge singlet real scalars whose stability is protected by an unbroken Z2× Z'2 symmetry and they are assumed to acquire no VEV after Spontaneous Symmetry Breaking. We explore the viable mass regions in the present two scalar DM model that is in accordance with the FIMP scenario. We also explore the upper limits of masses of the two components from the consideration of their self interactions.

Exploring communication and interaction skills at work among participants in individual placement and support.

PubMed

Lexén, Annika; Bejerholm, Ulrika

2016-07-01

Not all people with severe mental illness who attend Individual Placement and Support (IPS) gain and keep their jobs or work full time. Research has indicated a relationship between social disabilities and work performance in this group, and that support provided is often directed towards the social work environment. However, relationships between social skills performed in an authentic work setting and vocational outcomes have not been explored. To explore relationships between social communication and interaction skills and vocational outcomes among IPS service users in a Swedish context. Twenty-nine participants were appraised with the Assessment of Communication and Interaction Skills (ACIS-S) instrument, and their vocational data were registered. Correlations were estimated using Spearman's rho test with Bonferroni corrections at item level. Better communication and interaction skills were significantly correlated with increased working hours (rs = 0.64) and higher income (rs = 0.45). Increased working hours were related to assuming postures, asking questions, sharing information, and sustaining conversation in an appropriate manner. The results indicate that occupational therapists need to focus on social skills and accommodation of the social work environment in order to promote sustainable working careers among people with severe mental illness.

Interactive Exploration Robots: Human-Robotic Collaboration and Interactions

NASA Technical Reports Server (NTRS)

Fong, Terry

2017-01-01

For decades, NASA has employed different operational approaches for human and robotic missions. Human spaceflight missions to the Moon and in low Earth orbit have relied upon near-continuous communication with minimal time delays. During these missions, astronauts and mission control communicate interactively to perform tasks and resolve problems in real-time. In contrast, deep-space robotic missions are designed for operations in the presence of significant communication delay - from tens of minutes to hours. Consequently, robotic missions typically employ meticulously scripted and validated command sequences that are intermittently uplinked to the robot for independent execution over long periods. Over the next few years, however, we will see increasing use of robots that blend these two operational approaches. These interactive exploration robots will be remotely operated by humans on Earth or from a spacecraft. These robots will be used to support astronauts on the International Space Station (ISS), to conduct new missions to the Moon, and potentially to enable remote exploration of planetary surfaces in real-time. In this talk, I will discuss the technical challenges associated with building and operating robots in this manner, along with lessons learned from research conducted with the ISS and in the field.

Exploring interaction with 3D volumetric displays

NASA Astrophysics Data System (ADS)

Grossman, Tovi; Wigdor, Daniel; Balakrishnan, Ravin

2005-03-01

Volumetric displays generate true volumetric 3D images by actually illuminating points in 3D space. As a result, viewing their contents is similar to viewing physical objects in the real world. These displays provide a 360 degree field of view, and do not require the user to wear hardware such as shutter glasses or head-trackers. These properties make them a promising alternative to traditional display systems for viewing imagery in 3D. Because these displays have only recently been made available commercially (e.g., www.actuality-systems.com), their current use tends to be limited to non-interactive output-only display devices. To take full advantage of the unique features of these displays, however, it would be desirable if the 3D data being displayed could be directly interacted with and manipulated. We investigate interaction techniques for volumetric display interfaces, through the development of an interactive 3D geometric model building application. While this application area itself presents many interesting challenges, our focus is on the interaction techniques that are likely generalizable to interactive applications for other domains. We explore a very direct style of interaction where the user interacts with the virtual data using direct finger manipulations on and around the enclosure surrounding the displayed 3D volumetric image.

Exploration Medical System Technical Architecture Overview

NASA Technical Reports Server (NTRS)

Cerro, J.; Rubin, D.; Mindock, J.; Middour, C.; McGuire, K.; Hanson, A.; Reilly, J.; Burba, T.; Urbina, M.

2018-01-01

The Exploration Medical Capability (ExMC) Element Systems Engineering (SE) goals include defining the technical system needed to support medical capabilities for a Mars exploration mission. A draft medical system architecture was developed based on stakeholder needs, system goals, and system behaviors, as captured in an ExMC concept of operations document and a system model. This talk will discuss a high-level view of the medical system, as part of a larger crew health and performance system, both of which will support crew during Deep Space Transport missions. Other mission components, such as the flight system, ground system, caregiver, and patient, will be discussed as aspects of the context because the medical system will have important interactions with each. Additionally, important interactions with other aspects of the crew health and performance system are anticipated, such as health & wellness, mission task performance support, and environmental protection. This talk will highlight areas in which we are working with other disciplines to understand these interactions.

Exploring the Yeast Acetylome Using Functional Genomics

PubMed Central

Duffy, Supipi Kaluarachchi; Friesen, Helena; Baryshnikova, Anastasia; Lambert, Jean-Philippe; Chong, Yolanda T.; Figeys, Daniel; Andrews, Brenda

2014-01-01

SUMMARY Lysine acetylation is a dynamic posttranslational modification with a well-defined role in regulating histones. The impact of acetylation on other cellular functions remains relatively uncharacterized. We explored the budding yeast acetylome with a functional genomics approach, assessing the effects of gene overexpression in the absence of lysine deacetylases (KDACs). We generated a network of 463 synthetic dosage lethal (SDL) interactions involving class I and II KDACs, revealing many cellular pathways regulated by different KDACs. A biochemical survey of genes interacting with the KDAC RPD3 identified 72 proteins acetylated in vivo. In-depth analysis of one of these proteins, Swi4, revealed a role for acetylation in G1-specific gene expression. Acetylation of Swi4 regulates interaction with its partner Swi6, both components of the SBF transcription factor. This study expands our view of the yeast acetylome, demonstrates the utility of functional genomic screens for exploring enzymatic pathways, and provides functional information that can be mined for future studies. PMID:22579291

GrouseFlocks: steerable exploration of graph hierarchy space.

PubMed

Archambault, Daniel; Munzner, Tamara; Auber, David

2008-01-01

Several previous systems allow users to interactively explore a large input graph through cuts of a superimposed hierarchy. This hierarchy is often created using clustering algorithms or topological features present in the graph. However, many graphs have domain-specific attributes associated with the nodes and edges, which could be used to create many possible hierarchies providing unique views of the input graph. GrouseFlocks is a system for the exploration of this graph hierarchy space. By allowing users to see several different possible hierarchies on the same graph, the system helps users investigate graph hierarchy space instead of a single fixed hierarchy. GrouseFlocks provides a simple set of operations so that users can create and modify their graph hierarchies based on selections. These selections can be made manually or based on patterns in the attribute data provided with the graph. It provides feedback to the user within seconds, allowing interactive exploration of this space.

Three visualization approaches for communicating and exploring PIT tag data

USGS Publications Warehouse

Letcher, Benjamin; Walker, Jeffrey D.; O'Donnell, Matthew; Whiteley, Andrew R.; Nislow, Keith; Coombs, Jason

2018-01-01

As the number, size and complexity of ecological datasets has increased, narrative and interactive raw data visualizations have emerged as important tools for exploring and understanding these large datasets. As a demonstration, we developed three visualizations to communicate and explore passive integrated transponder tag data from two long-term field studies. We created three independent visualizations for the same dataset, allowing separate entry points for users with different goals and experience levels. The first visualization uses a narrative approach to introduce users to the study. The second visualization provides interactive cross-filters that allow users to explore multi-variate relationships in the dataset. The last visualization allows users to visualize the movement histories of individual fish within the stream network. This suite of visualization tools allows a progressive discovery of more detailed information and should make the data accessible to users with a wide variety of backgrounds and interests.

A web-portal for interactive data exploration, visualization, and hypothesis testing

PubMed Central

Bartsch, Hauke; Thompson, Wesley K.; Jernigan, Terry L.; Dale, Anders M.

2014-01-01

Clinical research studies generate data that need to be shared and statistically analyzed by their participating institutions. The distributed nature of research and the different domains involved present major challenges to data sharing, exploration, and visualization. The Data Portal infrastructure was developed to support ongoing research in the areas of neurocognition, imaging, and genetics. Researchers benefit from the integration of data sources across domains, the explicit representation of knowledge from domain experts, and user interfaces providing convenient access to project specific data resources and algorithms. The system provides an interactive approach to statistical analysis, data mining, and hypothesis testing over the lifetime of a study and fulfills a mandate of public sharing by integrating data sharing into a system built for active data exploration. The web-based platform removes barriers for research and supports the ongoing exploration of data. PMID:24723882

Preschoolers Explore Interactive Storybook Apps: The Effect on Word Recognition and Story Comprehension

ERIC Educational Resources Information Center

Zipke, Marcy

2017-01-01

Two experiments explored the effects of reading digital storybooks on tablet computers with 25 preschoolers, aged 4-5. In the first experiment, the students' word recognition scores were found to increase significantly more when students explored a digital storybook and employed the read-aloud function than when they were read to from a comparable…

Learning from Success as Leverage for a Professional Learning Community: Exploring an Alternative Perspective of School Improvement Process

ERIC Educational Resources Information Center

Schechter, Chen

2010-01-01

Background: Although the professional learning community as a means of improving student achievement has received growing support from researchers and practitioners alike, professionals are still exploring ways to develop interaction networks regarding teaching and learning issues. Purpose: This study explores the evolving stages of a collective…

Exploring Transition to Postgraduate Study: Shifting Identities in Interaction with Communities, Practice and Participation

ERIC Educational Resources Information Center

Tobbell, Jane; O'Donnell, Victoria; Zammit, Maria

2010-01-01

There has been relatively little research to date that has explored the transition to postgraduate study. This paper reports findings from a project (funded by the UK's Higher Education Academy) that sought to address this gap. The research project was ethnographic and explored university practice and student participation in five UK universities.…

The Interrelationships of Preadolescents' Student Characteristics Influencing Selection of Career Exploration Courses [And Abstract]. Industrial Arts Education Monograph No. 1.

ERIC Educational Resources Information Center

Meehan, Merrill L.

The study investigated the interaction of personal and environmental factors influencing seventh graders' selection of career exploration courses for increased exploration in the eighth grade. A stratified random sample (496 students) was drawn from the Pittsburgh Public School's Occupational, Vocational, and Technical Exploratory Program.…

Interacting with Petabytes of Earth Science Data using Jupyter Notebooks, IPython Widgets and Google Earth Engine

NASA Astrophysics Data System (ADS)

Erickson, T. A.; Granger, B.; Grout, J.; Corlay, S.

2017-12-01

The volume of Earth science data gathered from satellites, aircraft, drones, and field instruments continues to increase. For many scientific questions in the Earth sciences, managing this large volume of data is a barrier to progress, as it is difficult to explore and analyze large volumes of data using the traditional paradigm of downloading datasets to a local computer for analysis. Furthermore, methods for communicating Earth science algorithms that operate on large datasets in an easily understandable and reproducible way are needed. Here we describe a system for developing, interacting, and sharing well-documented Earth Science algorithms that combines existing software components: Jupyter Notebook: An open-source, web-based environment that supports documents that combine code and computational results with text narrative, mathematics, images, and other media. These notebooks provide an environment for interactive exploration of data and development of well documented algorithms. Jupyter Widgets / ipyleaflet: An architecture for creating interactive user interface controls (such as sliders, text boxes, etc.) in Jupyter Notebooks that communicate with Python code. This architecture includes a default set of UI controls (sliders, dropboxes, etc.) as well as APIs for building custom UI controls. The ipyleaflet project is one example that offers a custom interactive map control that allows a user to display and manipulate geographic data within the Jupyter Notebook. Google Earth Engine: A cloud-based geospatial analysis platform that provides access to petabytes of Earth science data via a Python API. The combination of Jupyter Notebooks, Jupyter Widgets, ipyleaflet, and Google Earth Engine makes it possible to explore and analyze massive Earth science datasets via a web browser, in an environment suitable for interactive exploration, teaching, and sharing. Using these environments can make Earth science analyses easier to understand and reproducible, which may increase the rate of scientific discoveries and the transition of discoveries into real-world impacts.

Between War and Peace: Interactional Patterns of Couples under Prolonged Uncertainty.

ERIC Educational Resources Information Center

Ben-David, Amith; Lavee, Yoav

1996-01-01

Explores how global and political issues affect microsystems like the marital unit. A variety of interactional patterns emerged in the observation of 30 couples marital interactions during a prolonged stressful situation. Couples reporting a deterioration of their relationship had more disagreements regarding the meaning of a peace process and its…

Exploring Peer Interaction among Multilingual Youth: New Possibilities and Challenges for Language and Literacy Learning

ERIC Educational Resources Information Center

Martin-Beltrán, Melinda

2017-01-01

Peer interactions are central to student experiences and present tremendous opportunities for language learning and consequences for educational equity, yet these opportunities have often been unrecognized and under-examined. This special issue offers new perspectives examining the potential of peer interaction to foster language, literacy and…

Language Maintenance in a Multilingual Family: Informal Heritage Language Lessons in Parent-Child Interactions

ERIC Educational Resources Information Center

Kheirkhah, Mina; Cekaite, Asta

2015-01-01

The present study explores language socialization patterns in a Persian-Kurdish family in Sweden and examines how "one-parent, one-language" family language policies are instantiated and negotiated in parent-child interactions. The data consist of video-recordings and ethnographic observations of family interactions, as well as…

The Complexity of the Affordance-Ability Relationship When Second-Grade Children Interact with Mathematics Virtual Manipulative Apps

ERIC Educational Resources Information Center

Tucker, Stephen I.; Moyer-Packenham, Patricia S.; Westenskow, Arla; Jordan, Kerry E.

2016-01-01

The purpose of this study was to explore relationships between app affordances and user abilities in second graders' interactions with mathematics virtual manipulative touchscreen tablet apps. The research questions focused on varying manifestations of affordance-ability relationships during children's interactions with mathematics virtual…

Exploring the Quality of Teacher-Child Interactions: The Soka Discourse in Practice

ERIC Educational Resources Information Center

Ikegami, Kiiko; Rivalland, Corine

2016-01-01

Numerous research has shown that quality of interactions between early childhood teachers and children contribute significantly to children's holistic development. Most literature on this topic comes from developed/Western countries and little is known about the kind of interactions occurring within the Soka kindergarten model. This article, based…

Enhancing Student-Student Online Interaction: Exploring the Study Buddy Peer Review Activity

ERIC Educational Resources Information Center

Madland, Colin; Richards, Griff

2016-01-01

The study buddy is a learning strategy employed in a graduate distance course to promote informal peer reviewing of assignments before submission. This strategy promotes student-student interaction and helps break the social isolation of distance learning. Given the concern by Arum and Roksa (2011) that student-student interaction may be…

Students' Peer Interactions within a Cohort and in Host Countries during a Short-Term Study Abroad

ERIC Educational Resources Information Center

Jessup-Anger, Jody E.; Aragones, Aileen

2013-01-01

In this qualitative case study, we explored students' peer interactions within their cohort and in the host countries during a short-term study abroad. Framed by Bronfenbrenner's (1993) ecological systems theory, findings revealed that students spent considerable energy reflecting on interactions with peers. The students considered themselves…

Parent-Child Interaction in Nigerian Families: Conversation Analysis, Context and Culture

ERIC Educational Resources Information Center

Burns, Annabel; Radford, Julie

2008-01-01

This paper uses a conversation analysis (CA) approach to explore parent-child interaction (PCI) within Nigerian families. We illustrate how speech and language therapists (SLTs), by using CA, can tailor recommendations according to the interactional style of each individual family that are consonant with the family's cultural beliefs. Three…

Interactions between Turkish Mothers and Preschool Children with Autism

ERIC Educational Resources Information Center

Diken, Ozlem; Mahoney, Gerald

2013-01-01

This study explored the relationship between Turkish mothers' style of interaction and the engagement of their preschool-aged children with autism. Data were collected from fifty mother-child dyads in which all children had diagnoses of autism. Video recordings of mother-child interaction were analyzed using the Turkish versions of the Maternal…

The Dimensionality and Correlates of Flow in Human-Computer Interactions.

ERIC Educational Resources Information Center

Webster, Jane; And Others

1993-01-01

Defines playfulness in human-computer interactions in terms of flow theory and explores the dimensionality of the flow concept. Two studies are reported that investigated the factor structure and correlates of flow in human-computer interactions: one examined MBA students using Lotus 1-2-3 spreadsheet software, and one examined employees using…

The Impact of Social Interaction on Student Learning

ERIC Educational Resources Information Center

Hurst, Beth; Wallace, Randall; Nixon, Sarah B.

2013-01-01

Due to the lack of student engagement in the common lecture-centered model, we explored a model of instructional delivery where our undergraduate and graduate classes were structured so that students had opportunities for daily interaction with each other. Specifically, we examined how students perceived the value of social interaction on their…

Interactions of two odorant-binding proteins from Cnaphalocrocis medinalis Güenée (Lepidoptera: Pyralidae)

USDA-ARS?s Scientific Manuscript database

It is well known that the odorant-binding proteins (OBPs) play important roles in insect olfactory systems. However, little attention has been paid to interactions among different OBPs within the same insect antennal sensilla. To explore the interactions of OBPs in olfactory coding in the rice leaff...

Hold on Tight or Let Go: Exploring the Parental Role in First-Year Students' College Adjustment

ERIC Educational Resources Information Center

Sax, Linda J.; Weintraub, Dayna S.

2016-01-01

Using a sample of 995 students living in residential housing at a selective, public research university, this study examined the relationship between student-parent interactions and adjustment to college and investigated differences between student-mother interactions and student-father interactions. Results indicate that students are generally…

Sense of Community in Graduate Online Education: Contribution of Learner to Learner Interaction

ERIC Educational Resources Information Center

Shackelford, Jo L.; Maxwell, Marge

2012-01-01

Distance learning technologies offer a multitude of ways to build interaction into online courses to support learning. Based on social constructivism theory, this study explored which types of interaction are most predictive of students' sense of community in online graduate courses at a regional comprehensive university. Surveys were used to…

Understanding the Use of Interactive Whiteboards in Primary Science

ERIC Educational Resources Information Center

Sweeney, Trudy

2013-01-01

This paper explores the dimensions of change experienced by a specialist primary science teacher in Australia as she attempted to embed an interactive whiteboard into her practice as a tool to enhance interactive teaching and learning. This paper uses the theoretical frameworks of activity theory and the stages of concern to understand the…

Interactive Metronome Training in Children with Attention Deficit and Developmental Coordination Disorders

ERIC Educational Resources Information Center

Cosper, Sharon M.; Lee, Gregory P.; Peters, Susan Beth; Bishop, Elizabeth

2009-01-01

The objective of this study was to examine the efficacy of Interactive Metronome (Interactive Metronome, Sunrise, Florida, USA) training in a group of children with mixed attentional and motor coordination disorders to further explore which subcomponents of attentional control and motor functioning the training influences. Twelve children who had…

Exploring Student and Supervisor Interaction during the SciPro Thesis Process: Two Use Cases

ERIC Educational Resources Information Center

Hansen, Preben; Hansson, Henrik

2017-01-01

Common problems identified by students during their interaction with supervisors are too little instructions as well as infrequent and insufficient supervisor feedback. The SciPro system has been developed to tackle these problems. This paper describes, analyzes and discusses the interaction between students and supervisors using the SciPro…

Exploring the Technical Adequacy of the Family Interaction Inventory.

ERIC Educational Resources Information Center

Robinson, Christopher S.; And Others

There are no available measures that assess family interaction from a comprehensive theoretical perspective. This study reports analyses of the measurement integrity of scores from a measure developed to offer a comprehensive assessment. The preliminary version of the Family Interaction Inventory (FII) is a 24-scale instrument with 5 items per…

Interactional Metadiscourse in Turkish Postgraduates' Academic Texts: A Comparative Study of How They Introduce and Conclude

ERIC Educational Resources Information Center

Akbas, Erdem

2012-01-01

This study explores interactional metadiscourse resources in master's dissertations (introductions and conclusions) of Turkish students written in Turkish and English. Interactional resources were identified according to Hyland and Tse's (2004) framework by using WordSmith Tools (5.0). A statistically significant difference between two groups of…

Imitation, Interaction and Imagery: Learning to Improvise Drawing with Music

ERIC Educational Resources Information Center

Huovinen, Erkki; Manneberg, Avigail

2013-01-01

This article describes a project in which undergraduate students of beginning drawing were brought together with free improvising musicians to explore interaction in collective real-time art-making. Following a series of guided rehearsals, the students were free to choose their own strategies for interactive group projects. We discuss these…

Communicative interactions involving plants: information, evolution, and ecology.

PubMed

Mescher, Mark C; Pearse, Ian S

2016-08-01

The role of information obtained via sensory cues and signals in mediating the interactions of organisms with their biotic and abiotic environments has been a major focus of work on sensory and behavioral ecology. Information-mediated interactions also have important implications for broader ecological patterns emerging at the community and ecosystem levels that are only now beginning to be explored. Given the extent to which plants dominate the sensory landscapes of terrestrial ecosystems, information-mediated interactions involving plants should be a major focus of efforts to elucidate these broader patterns. Here we explore how such efforts might be enhanced by a clear understanding of information itself-a central and potentially unifying concept in biology that has nevertheless been the subject of considerable confusion-and of its relationship to adaptive evolution and ecology. We suggest that information-mediated interactions should be a key focus of efforts to more fully integrate evolutionary biology and ecology. Copyright © 2016 Elsevier Ltd. All rights reserved.

Group-based strategy diffusion in multiplex networks with weighted values

NASA Astrophysics Data System (ADS)

Yu, Jianyong; Jiang, J. C.; Xiang, Leijun

2017-03-01

The information diffusion of multiplex social networks has received increasing interests in recent years. Actually, the multiplex networks are made of many communities, and it should be gotten more attention for the influences of community level diffusion, besides of individual level interactions. In view of this, this work explores strategy interactions and diffusion processes in multiplex networks with weighted values from a new perspective. Two different groups consisting of some agents with different influential strength are firstly built in each layer network, the authority and non-authority groups. The strategy interactions between different groups in intralayer and interlayer networks are performed to explore community level diffusion, by playing two classical strategy games, Prisoner's Dilemma and Snowdrift Game. The impact forces from the different groups and the reactive forces from individual agents are simultaneously taken into account in intralayer and interlayer interactions. This paper reveals and explains the evolutions of cooperation diffusion and the influences of interlayer interaction tight degrees in multiplex networks with weighted values. Some thresholds of critical parameters of interaction degrees and games parameters settings are also discussed in group-based strategy diffusion.

Hess Deep Interactive Lab: Exploring the Structure and Formation of the Oceanic Crust through Hands-On Models and Online Tools

NASA Astrophysics Data System (ADS)

Kurtz, N.; Marks, N.; Cooper, S. K.

2014-12-01

Scientific ocean drilling through the International Ocean Discovery Program (IODP) has contributed extensively to our knowledge of Earth systems science. However, many of its methods and discoveries can seem abstract and complicated for students. Collaborations between scientists and educators/artists to create accurate yet engaging demonstrations and activities have been crucial to increasing understanding and stimulating interest in fascinating geological topics. One such collaboration, which came out of Expedition 345 to the Hess Deep Rift, resulted in an interactive lab to explore sampling rocks from the usually inacessible lower oceanic crust, offering an insight into the geological processes that form the structure of the Earth's crust. This Hess Deep Interactive Lab aims to explain several significant discoveries made by oceanic drilling utilizing images of actual thin sections and core samples recovered from IODP expeditions. . Participants can interact with a physical model to learn about the coring and drilling processes, and gain an understanding of seafloor structures. The collaboration of this lab developed as a need to explain fundamental notions of the ocean crust formed at fast-spreading ridges. A complementary interactive online lab can be accessed at www.joidesresolution.org for students to engage further with these concepts. This project explores the relationship between physical and on-line models to further understanding, including what we can learn from the pros and cons of each.

Geometric quantification of features in large flow fields.

PubMed

Kendall, Wesley; Huang, Jian; Peterka, Tom

2012-01-01

Interactive exploration of flow features in large-scale 3D unsteady-flow data is one of the most challenging visualization problems today. To comprehensively explore the complex feature spaces in these datasets, a proposed system employs a scalable framework for investigating a multitude of characteristics from traced field lines. This capability supports the examination of various neighborhood-based geometric attributes in concert with other scalar quantities. Such an analysis wasn't previously possible because of the large computational overhead and I/O requirements. The system integrates visual analytics methods by letting users procedurally and interactively describe and extract high-level flow features. An exploration of various phenomena in a large global ocean-modeling simulation demonstrates the approach's generality and expressiveness as well as its efficacy.

An interactional ethnographic study of the construction of literate practices of science and writing in a university science classroom

NASA Astrophysics Data System (ADS)

Sena, Nuno Afonso De Freitas Lopes De

An interactional ethnographic study informed by a sociocultural perspective was conducted to examine how a professor and students discursively and interactionally shaped the basis for engaging in the work of a community of geologists. Specifically, the study examined the role the Question of the Day, an interactive writing activity in the lecture, in affording students opportunities for learning the literate practices of science and how to incorporate them in thinking critically. A writing-intensive, introductory oceanography course given in the Geological Sciences Department was chosen because the professor designed it to emphasize writing in the discipline and science literacy within a science inquiry framework. The study was conducted in two phases: a pilot in 2002 and the current study in the Spring Quarter of 2003. Grounded in the view that members in a classroom construct a culture, this study explored the daily construction of the literate practices of science and writing. This view of classrooms was informed by four bodies of research: interactional ethnography, sociolinguistics sociology of science and Writing In the Disciplines. Through participant observation, data were collected in the lecture and laboratory settings in the form of field notes, video, interviews, and artifacts to explore issues of science literacy in discourse, social action, and writing. Examination of participation in the Question of the Day interactive writing activity revealed that it played a key role in initiating and supporting a view of science and inquiry. As the activity permitted collaboration, it encouraged students to engage in the social process to critically explore a discourse of science and key practices with and through their writing. In daily interaction, participants were shown to take up social positions as scientist and engage in science inquiry to explore theory, examine data, and articulately reformulate knowledge in making oral and written scientific arguments. The activity was also shown to provide the professor with a valuable resource to inform his instructional practice, which resulted in enriching the experience of science of students by aligning lectures to address particular concerns. Implications for theory, the teaching of Writing across the Curriculum, and science instruction are discussed.

Computer simulations for the Mars Atmospheric and Volatile EvolutioN (MAVEN) mission through NASA's "Project Spectra!"

NASA Astrophysics Data System (ADS)

Christofferson, R.; Wood, E. L.; Euler, G.

2012-12-01

"Project Spectra!" is a standards-based light science and engineering program on solar system exploration that includes both hands-on paper and pencil activities as well as Flash-based computer games that help students solidify understanding of high-level planetary and solar physics. Using computer interactive games where students experience and manipulate the information makes abstract concepts accessible. Visualizing lessons with multi-media tools solidifies understanding and retention of knowledge. Since students can choose what to watch and explore, the interactives accommodate a broad range of learning styles. Students can go back and forth through the interactives if they've missed a concept or wish to view something again. In the end, students are asked critical thinking questions and conduct web-based research. As a part of the Mars Atmospheric and Volatile EvolutioN (MAVEN) mission education programming, we've developed two new "Project Spectra!" interactives that go hand-in-hand with a paper and pencil activity. The MAVEN mission will study volatiles in the upper atmosphere to help piece together Mars' climate history. In the first interactive, students explore black body radiation, albedo, and a simplified greenhouse effect to establish what factors contribute to overall planetary temperature and how they contribute. Students are asked to create a scenario in which a planet they build and design is able to maintain liquid water on the surface. In the second interactive, students are asked to consider Mars and the conditions needed for Mars to support water on the surface, keeping some variables fixed. Ideally, students will walk away with the very basic and critical elements required for climate studies, which has far-reaching implications beyond the study of Mars. These interactives are currently being pilot tested at Arvada High School in Colorado.

Behavioral Differences Between Late Preweanling and Adult Female Sprague-Dawley Rat Exploration of Animate and Inanimate Stimuli and Food

PubMed Central

Smith, Kiersten S.; Morrell, Joan I.

2010-01-01

The late preweanling rat has potential as a preclinical model for disorders initially manifested in early childhood that are characterized by dysfunctional interactions with specific stimuli (e.g., obsessive-compulsive disorder and autism). No reports, however, of specific-stimulus exploration in the late preweanling rat are found in the literature. We examined the behavioral responses of normal late preweanling (PND 18-19) and adult rats when presented with exemplars of categorically-varied stimuli, including inanimate objects systematically varied in size and interactive properties, biological stimuli, and food. Preweanlings were faster to initiate specific stimulus exploration and were more interactive with most specific stimuli than adults; the magnitude of these preweanling-adult quantitative differences ranged from fairly small to very large depending upon the stimulus. In contrast, preweanlings were adult-like in their interaction with food and prey. Preweanling response to some stimuli, for example to live pups, was qualitatively different from that of adults; the preweanling behavioral repertoire was characterized by pup-seeking while the adult response was characterized by pup-avoidance. The specific stimulus interactions of preweanlings were less impacted than those of adults by the time of day of testing and placement of a stimulus in an anxiety-provoking location. The impact of novelty was stimulus dependent. The differences in interactions of preweanlings versus adults with specific stimuli suggests that CNS systems underlying these behavior patterns are at different stages of immaturity at PND 18 such that there may be an array of developmental trajectories for various categories of specific stimuli. These data provide a basis for the use of the preweanling as a preclinical model for understanding and medicating human disorders during development that are characterized by dysfunctional interactions with specific stimuli. PMID:21056059

Computer simulations for the Mars Atmospheric and Volatile EvolutioN (MAVEN) mission through NASA's 'Project Spectra!'

NASA Astrophysics Data System (ADS)

Wood, E. L.

2013-12-01

'Project Spectra!' is a standards-based light science and engineering program on solar system exploration that includes both hands-on paper and pencil activities as well as Flash-based computer games that help students solidify understanding of high-level planetary and solar physics. Using computer interactive games where students experience and manipulate the information makes abstract concepts accessible. Visualizing lessons with multi-media tools solidifies understanding and retention of knowledge. Since students can choose what to watch and explore, the interactives accommodate a broad range of learning styles. Students can go back and forth through the interactives if they've missed a concept or wish to view something again. In the end, students are asked critical thinking questions and conduct web-based research. As a part of the Mars Atmospheric and Volatile EvolutioN (MAVEN) mission education programming, we've developed two new 'Project Spectra!' interactives that go hand-in-hand with a paper and pencil activity. The MAVEN mission will study volatiles in the upper atmosphere to help piece together Mars' climate history. In the first interactive, students explore black body radiation, albedo, and a simplified greenhouse effect to establish what factors contribute to overall planetary temperature and how they contribute. Students are asked to create a scenario in which a planet they build and design is able to maintain liquid water on the surface. In the second interactive, students are asked to consider Mars and the conditions needed for Mars to support water on the surface, keeping some variables fixed. Ideally, students will walk away with the very basic and critical elements required for climate studies, which has far-reaching implications beyond the study of Mars. These interactives were pilot tested at Arvada High School in Colorado.

A novel approach to exploring potential interactions among single-nucleotide polymorphisms of inflammation genes in gliomagenesis: an exploratory case-only study.

PubMed

Amirian, E Susan; Scheurer, Michael E; Liu, Yanhong; D'Amelio, Anthony M; Houlston, Richard S; Etzel, Carol J; Shete, Sanjay; Swerdlow, Anthony J; Schoemaker, Minouk J; McKinney, Patricia A; Fleming, Sarah J; Muir, Kenneth R; Lophatananon, Artitaya; Bondy, Melissa L

2011-08-01

Despite extensive research on the topic, glioma etiology remains largely unknown. Exploration of potential interactions between single-nucleotide polymorphisms (SNP) of immune genes is a promising new area of glioma research. The case-only study design is a powerful and efficient design for exploring possible multiplicative interactions between factors that are independent of one another. The purpose of our study was to use this exploratory design to identify potential pair wise SNP-SNP interactions from genes involved in several different immune-related pathways for investigation in future studies. The study population consisted of two case groups: 1,224 histologic confirmed, non-Hispanic white glioma cases from the United States and a validation population of 634 glioma cases from the United Kingdom. Polytomous logistic regression, in which one SNP was coded as the outcome and the other SNP was included as the exposure, was utilized to calculate the ORs of the likelihood of cases simultaneously having the variant alleles of two different SNPs. Potential interactions were examined only between SNPs located in different genes or chromosomes. Using this data mining strategy, we found 396 significant SNP-SNP interactions among polymorphisms of immune-related genes that were present in both the U.S. and U.K. study populations. This exploratory study was conducted for the purpose of hypothesis generation, and thus has provided several new hypotheses that can be tested using traditional case-control study designs to obtain estimates of risk. This is the first study, to our knowledge, to take this novel approach to identifying SNP-SNP interactions relevant to glioma etiology. ©2011 AACR.

Pseudohaptic interaction with knot diagrams

NASA Astrophysics Data System (ADS)

Weng, Jianguang; Zhang, Hui

2012-07-01

To make progress in understanding knot theory, we need to interact with the projected representations of mathematical knots, which are continuous in three dimensions (3-D) but significantly interrupted in the projective images. One way to achieve such a goal is to design an interactive system that allows us to sketch two-dimensional (2-D) knot diagrams by taking advantage of a collision-sensing controller and explore their underlying smooth structures through a continuous motion. Recent advances of interaction techniques have been made that allow progress in this direction. Pseudohaptics that simulate haptic effects using pure visual feedback can be used to develop such an interactive system. We outline one such pseudohaptic knot diagram interface. Our interface derives from the familiar pencil-and-paper process of drawing 2-D knot diagrams and provides haptic-like sensations to facilitate the creation and exploration of knot diagrams. A centerpiece of the interaction model simulates a physically reactive mouse cursor, which is exploited to resolve the apparent conflict between the continuous structure of the actual smooth knot and the visual discontinuities in the knot diagram representation. Another value in exploiting pseudohaptics is that an acceleration (or deceleration) of the mouse cursor (or surface locator) can be used to indicate the slope of the curve (or surface) of which the projective image is being explored. By exploiting these additional visual cues, we proceed to a full-featured extension to a pseudohaptic four-dimensional (4-D) visualization system that simulates the continuous navigation on 4-D objects and allows us to sense the bumps and holes in the fourth dimension. Preliminary tests of the software show that main features of the interface overcome some expected perceptual limitations in our interaction with 2-D knot diagrams of 3-D knots and 3-D projective images of 4-D mathematical objects.

Interactive Video: Why Trainers Are Tuning In.

ERIC Educational Resources Information Center

Broderick, Richard

1982-01-01

The uses of interactive video are explored through various case studies. They include cardiopulmonary resuscitation training for the Dallas American Heart Association, Ford Motor Company dealership training, employee training at the Los Angeles Plutonium Facility, and others. (CT)

Racial Bias in Drivers' Yielding Behavior at Crosswalks : Understanding the Effect

DOT National Transportation Integrated Search

2017-10-01

This project explores social identity factors (race and gender) that influence drivers' behavior in interactions with pedestrians at crosswalks. One dangerous potential point of conflict for pedestrians within the transportation system is interaction...

HExpoChem: a systems biology resource to explore human exposure to chemicals.

PubMed

Taboureau, Olivier; Jacobsen, Ulrik Plesner; Kalhauge, Christian; Edsgärd, Daniel; Rigina, Olga; Gupta, Ramneek; Audouze, Karine

2013-05-01

Humans are exposed to diverse hazardous chemicals daily. Although an exposure to these chemicals is suspected to have adverse effects on human health, mechanistic insights into how they interact with the human body are still limited. Therefore, acquisition of curated data and development of computational biology approaches are needed to assess the health risks of chemical exposure. Here we present HExpoChem, a tool based on environmental chemicals and their bioactivities on human proteins with the objective of aiding the qualitative exploration of human exposure to chemicals. The chemical-protein interactions have been enriched with a quality-scored human protein-protein interaction network, a protein-protein association network and a chemical-chemical interaction network, thus allowing the study of environmental chemicals through formation of protein complexes and phenotypic outcomes enrichment. HExpoChem is available at http://www.cbs.dtu.dk/services/HExpoChem-1.0/.

A Study of Attitude and Knowledge of the Psychiatry Resident Doctors toward Clinician–Pharmaceutical Industry Interaction

PubMed Central

Balhara, Yatan Pal Singh; Mathur, Shachi; Anand, Nikhilesh

2012-01-01

Background: Pharmaceutical industry and clinicians are the two important stakeholders in the modern-day health care. However, concerns have been expressed about the lack of congruence between the goals of these two. Aims: The current study aimed at exploring the knowledge and attitude of the psychiatry resident doctors toward the clinician–pharmaceutical industry interaction and also at exploring the knowledge of the residents about the new Medical Council of India guidelines on this issue. Materials and Methods: The survey was conducted among psychiatry residents. Descriptive statistics with frequency distribution was carried out by using SPSS version 17.0. Results: It had a good response rate of around 90%. The survey reveals the knowledge and attitude of the psychiatry residents toward the psychiatrist–pharmaceutical industry interaction. Conclusions: The survey provides understanding in knowledge and attitude of the psychiatry residents towards the psychiatrist-pharmaceutical industry interaction. PMID:22661810

The Future of Web Maps in Next Generation Textbooks

NASA Astrophysics Data System (ADS)

DiBiase, D.; Prasad, S.

2014-12-01

The reformation of the "Object Formerly Known as Textbook" (coined by the Chronicle of Higher Education) toward a digital future is underway. Emerging nextgen texts look less like electronic books ("ebooks") and more like online courseware. In addition to text and illustrations, nextgen textbooks for STEM subjects are likely to combine quizzes, grade management tools, support for social learning, and interactive media including web maps. Web maps are interactive, multi-scale, online maps that enable teachers and learners to explore, interrogate, and mash up the wide variety of map layers available in the cloud. This presentation will show how web maps coupled with interactive quizzes enable students' purposeful explorations and interpretations of spatial patterns related to humankind's interactions with the earth. Attendees will also learn about Esri's offer to donate ArcGIS Online web mapping subscriptions to every U.S. school as part of the President Obama's ConnectED initiative.

A crystal plasticity-based study of the relationship between microstructure and ultra-high-cycle fatigue life in nickel titanium alloys

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moore, John A.; Frankel, Dana; Prasannavenkatesan, Rajesh

Nickel Titanium (NiTi) alloys are often used in biomedical devices where failure due to mechanical fatigue is common. For other alloy systems, computational models have proven an effective means of determining the relationship between microstructural features and fatigue life. This work will extend the subset of those models which were based on crystal plasticity to examine the relationship between microstructure and fatigue life in NiTi alloys. It will explore the interaction between a spherical inclusion and the material’s free surface along with several NiTi microstructures reconstructed from 3D imaging. This work will determine the distance at which the free surfacemore » interacts with an inclusion and the effect of applied strain of surface-inclusion interaction. The effects of inclusion-inclusion interaction, matrix voiding, and matrix strengthening are explored and ranked with regards to their influence on fatigue life.« less

Three-dimensional co-culture models to study prostate cancer growth, progression, and metastasis to bone.

PubMed

Wang, Ruoxiang; Xu, Jianchun; Juliette, Lisa; Castilleja, Agapito; Love, John; Sung, Shian-Ying; Zhau, Haiyen E; Goodwin, Thomas J; Chung, Leland W K

2005-10-01

Cancer-stromal interaction results in the co-evolution of both the cancer cells and the surrounding host stromal cells. As a consequence of this interaction, cancer cells acquire increased malignant potential and stromal cells become more inductive. In this review we suggest that cancer-stromal interaction can best be investigated by three-dimensional (3D) co-culture models with the results validated by clinical specimens. We showed that 3D culture promoted bone formation in vitro, and explored for the first time, with the help of the astronauts of the Space Shuttle Columbia, the co-culture of human prostate cancer and bone cells to further understand the interactions between these cells. Continued exploration of cancer growth under 3D conditions will rapidly lead to new discoveries and ultimately to improvements in the treatment of men with hormonal refractory prostate cancer.

A crystal plasticity-based study of the relationship between microstructure and ultra-high-cycle fatigue life in nickel titanium alloys

DOE PAGES

Moore, John A.; Frankel, Dana; Prasannavenkatesan, Rajesh; ...

2016-06-06

Nickel Titanium (NiTi) alloys are often used in biomedical devices where failure due to mechanical fatigue is common. For other alloy systems, computational models have proven an effective means of determining the relationship between microstructural features and fatigue life. This work will extend the subset of those models which were based on crystal plasticity to examine the relationship between microstructure and fatigue life in NiTi alloys. It will explore the interaction between a spherical inclusion and the material’s free surface along with several NiTi microstructures reconstructed from 3D imaging. This work will determine the distance at which the free surfacemore » interacts with an inclusion and the effect of applied strain of surface-inclusion interaction. The effects of inclusion-inclusion interaction, matrix voiding, and matrix strengthening are explored and ranked with regards to their influence on fatigue life.« less

Towards an acoustical platform for many-body spin emulation: Transmon qubits patterned on a piezoelectric material

NASA Astrophysics Data System (ADS)

Moores, Brad A.; Sletten, Lucas R.; Viennot, Jeremie; Lehnert, K. W.

Man-made systems of interacting qubits are a promising and powerful way of exploring many-body spin physics beyond classical computation. Although transmon qubits are perhaps the most advanced quantum computing technology, building a system of such qubits designed to emulate a system of many interacting spins is hindered by the mismatch of scales between the transmons and the electromagnetic modes that couple them. We propose a strategy to overcome this mismatch by using surface acoustic waves, which couple to qubits piezoelectrically and have micron wavelengths at GHz frequencies. In this talk, we will present characterizations of transmon qubits fabricated on a piezoelectric material, and show that their coherence properties are sufficient to explore acoustically mediated qubit interactions.

Collaborative Micro Aerial Vehicle Exploration of Outdoor Environments

DTIC Science & Technology

2010-02-01

with accelerometer or multitouch capabilities have also simply followed the same WYSIWYG paradigm. Finally, no HRI research exists on interacting ...Nudge Control relies on multimodal interaction ( multitouch gestures and tilting) to create a rich control interaction without cluttering the display...used in one of two different modes. NG mode uses a set of tilting gestures while CT mode uses multitouch gestures to interact with the vehicle. Both of

Using video-annotation software to identify interactions in group therapies for schizophrenia: assessing reliability and associations with outcomes.

PubMed

Orfanos, Stavros; Akther, Syeda Ferhana; Abdul-Basit, Muhammad; McCabe, Rosemarie; Priebe, Stefan

2017-02-10

Research has shown that interactions in group therapies for people with schizophrenia are associated with a reduction in negative symptoms. However, it is unclear which specific interactions in groups are linked with these improvements. The aims of this exploratory study were to i) develop and test the reliability of using video-annotation software to measure interactions in group therapies in schizophrenia and ii) explore the relationship between interactions in group therapies for schizophrenia with clinically relevant changes in negative symptoms. Video-annotation software was used to annotate interactions from participants selected across nine video-recorded out-patient therapy groups (N = 81). Using the Individual Group Member Interpersonal Process Scale, interactions were coded from participants who demonstrated either a clinically significant improvement (N = 9) or no change (N = 8) in negative symptoms at the end of therapy. Interactions were measured from the first and last sessions of attendance (>25 h of therapy). Inter-rater reliability between two independent raters was measured. Binary logistic regression analysis was used to explore the association between the frequency of interactive behaviors and changes in negative symptoms, assessed using the Positive and Negative Syndrome Scale. Of the 1275 statements that were annotated using ELAN, 1191 (93%) had sufficient audio and visual quality to be coded using the Individual Group Member Interpersonal Process Scale. Rater-agreement was high across all interaction categories (>95% average agreement). A higher frequency of self-initiated statements measured in the first session was associated with improvements in negative symptoms. The frequency of questions and giving advice measured in the first session of attendance was associated with improvements in negative symptoms; although this was only a trend. Video-annotation software can be used to reliably identify interactive behaviors in groups for schizophrenia. The results suggest that proactive communicative gestures, as assessed by the video-analysis, predict outcomes. Future research should use this novel method in larger and clinically different samples to explore which aspects of therapy facilitate such proactive communication early on in therapy.

RealSurf - A Tool for the Interactive Visualization of Mathematical Models

NASA Astrophysics Data System (ADS)

Stussak, Christian; Schenzel, Peter

For applications in fine art, architecture and engineering it is often important to visualize and to explore complex mathematical models. In former times there were static models of them collected in museums respectively in mathematical institutes. In order to check their properties for esthetical reasons it could be helpful to explore them interactively in 3D in real time. For the class of implicitly given algebraic surfaces we developed the tool RealSurf. Here we give an introduction to the program and some hints for the design of interesting surfaces.

Using immersive media and digital technology to communicate Earth Science

NASA Astrophysics Data System (ADS)

Kapur, Ravi

2016-04-01

A number of technologies in digital media and interactivity have rapidly advanced and are now converging to enable rich, multi-sensoral experiences which create opportunities for both digital art and science communication. Techniques used in full-dome film-making can now be deployed in virtual reality experiences; gaming technologies can be utilised to explore real data sets; and collaborative interactivity enable new forms of public artwork. This session will explore these converging trends through a number of emerging and forthcoming projects dealing with Earth science, climate change and planetary science.

Exploring Peer Relationships, Friendships and Group Work Dynamics in Higher Education: Applying Social Network Analysis

ERIC Educational Resources Information Center

Mamas, Christoforos

2018-01-01

This study primarily applied social network analysis (SNA) to explore the relationship between friendships, peer social interactions and group work dynamics within a higher education undergraduate programme in England. A critical case study design was adopted so as to allow for an in-depth exploration of the students' voice. In doing so, the views…

Investigating Teachers' Exploration of a Professional Development Website: An Innovative Approach to Understanding the Factors that Motivate Teachers to Use Internet-Based Resources

ERIC Educational Resources Information Center

Beach, Pamela; Willows, Dale

2014-01-01

This qualitative study examined an innovative methodology, combining screen capture technology and a retrospective think aloud, for exploring the use of Internet-based resources by elementary teachers. Pre-service and in-service teachers explored "The Balanced Literacy Diet," a free, interactive, and evidenced-informed professional…

Conversational Pedagogy: Exploring Interactions between a Teaching Artist and Young Learners during Visual Arts Experiences

ERIC Educational Resources Information Center

Eckhoff, Angela

2013-01-01

In many early childhood classrooms, visual arts experiences occur around a communal arts table. A shared workspace allows for spontaneous conversation and exploration of the art-making process of peers and teachers. In this setting, conversation can play an important role in visual arts experiences as children explore new media, skills, and ideas.…

Exploring the Interaction Mechanism Between Cyclopeptide DC3 and Androgen Receptor Using Molecular Dynamics Simulations and Free Energy Calculations

PubMed Central

Zhang, Huimin; Song, Tianqing; Yang, Yizhao; Fu, Chenggong; Li, Jiazhong

2018-01-01

Androgen receptor (AR) is a key target in the discovery of anti-PCa (Prostate Cancer) drugs. Recently, a novel cyclopeptide Diffusa Cyclotide-3 (DC3), isolated from Hedyotisdiffusa, has been experimentally demonstrated to inhibit the survival and growth of LNCap cells, which typically express T877A-mutated AR, the most frequently detected point mutation of AR in castration-resistant prostate cancer (CRPC). But the interaction mechanism between DC3 and AR is not clear. Here in this study we aim to explore the possible binding mode of DC3 to T877A-mutated AR from molecular perspective. Firstly, homology modeling was employed to construct the three-dimensional structure of the cyclopeptide DC3 using 2kux.1.A as the template. Then molecular docking, molecular dynamics (MD) simulations, and molecular mechanics/generalized Born surface area (MM-GBSA) methods were performed to determine the bind site and explore the detailed interaction mechanism of DC3-AR complex. The obtained results suggested that the site formed by H11, loop888-893, and H12 (site 2) was the most possible position of DC3 binding to AR. Besides, hydrogen bonds, hydrophobic, and electrostatic interactions play dominant roles in the recognition and combination of DC3-AR complex. The essential residues dominant in each interaction were specifically revealed. This work facilitates our understanding of the interaction mechanism of DC3 binding to AR at the molecular level and contributes to the rational cyclopeptide drug design for prostate cancer. PMID:29755968

Exploring the Interaction Mechanism between Cyclopeptide DC3 and Androgen Receptor Using Molecular Dynamics Simulations and Free Energy Calculations

NASA Astrophysics Data System (ADS)

Zhang, Huimin; Song, Tianqing; Yang, Yizhao; Fu, Chenggong; Li, Jiazhong

2018-04-01

Androgen receptor (AR) is a key target in the discovery of anti-PCa (Prostate Cancer) drugs. Recently, a novel cyclopeptide Diffusa Cyclotide-3 (DC3), isolated from Hedyotisdiffusa, has been experimentally demonstrated to inhibit the survival and growth of LNCap cells, which typically express T877A-mutated AR, the most frequently detected point mutation of AR in castration-resistant prostate cancer (CRPC). But the interaction mechanism between DC3 and AR is not clear. Here in this study we aim to explore the possible binding mode of DC3 to T877A-mutated AR from molecular perspective. Firstly, homology modeling was employed to construct the three-dimensional structure of the cyclopeptide DC3 using 2kux.1.A as the template. Then molecular docking, molecular dynamics (MD) simulations and molecular mechanics/generalized Born surface area (MM-GBSA) methods were performed to determine the bind site and explore the detailed interaction mechanism of DC3-AR complex. The obtained results suggested that the site formed by H11, loop888-893 and H12 (site 2) was the most possible position of DC3 binding to AR. Besides, hydrogen bonds, hydrophobic and electrostatic interactions play dominant roles in the recognition and combination of DC3-AR complex. The essential residues dominant in each interaction were specifically revealed. This work facilitates our understanding of the interaction mechanism of DC3 binding to AR at the molecular level and contributes to the rational cyclopeptide drug design for prostate cancer.

Exploring the Interaction Mechanism Between Cyclopeptide DC3 and Androgen Receptor Using Molecular Dynamics Simulations and Free Energy Calculations.

PubMed

Zhang, Huimin; Song, Tianqing; Yang, Yizhao; Fu, Chenggong; Li, Jiazhong

2018-01-01

Androgen receptor (AR) is a key target in the discovery of anti-PCa (Prostate Cancer) drugs. Recently, a novel cyclopeptide Diffusa Cyclotide-3 (DC3), isolated from Hedyotisdiffusa , has been experimentally demonstrated to inhibit the survival and growth of LNCap cells, which typically express T877A-mutated AR, the most frequently detected point mutation of AR in castration-resistant prostate cancer (CRPC). But the interaction mechanism between DC3 and AR is not clear. Here in this study we aim to explore the possible binding mode of DC3 to T877A-mutated AR from molecular perspective. Firstly, homology modeling was employed to construct the three-dimensional structure of the cyclopeptide DC3 using 2kux.1.A as the template. Then molecular docking, molecular dynamics (MD) simulations, and molecular mechanics/generalized Born surface area (MM-GBSA) methods were performed to determine the bind site and explore the detailed interaction mechanism of DC3-AR complex. The obtained results suggested that the site formed by H11, loop888-893, and H12 (site 2) was the most possible position of DC3 binding to AR. Besides, hydrogen bonds, hydrophobic, and electrostatic interactions play dominant roles in the recognition and combination of DC3-AR complex. The essential residues dominant in each interaction were specifically revealed. This work facilitates our understanding of the interaction mechanism of DC3 binding to AR at the molecular level and contributes to the rational cyclopeptide drug design for prostate cancer.

The Nature and Level of Learner-Learner Interaction in a Chemistry Massive Open Online Course (MOOC)

ERIC Educational Resources Information Center

Tawfik, Andrew A.; Reeves, Todd D.; Stich, Amy E.; Gill, Anila; Hong, Chenda; McDade, Joseph; Pillutla, Venkata Sai; Zhou, Xiaoshu; Giabbanelli, Philippe J.

2017-01-01

Similar to other online courses, massive open online courses (MOOCs) often rely on learner-learner interaction as a mechanism to promote learning. However, little is known at present about learner-learner interaction in these nascent informal learning environments. While some studies have explored MOOC participant perceptions of learner-learner…

Is AIBO Real? Understanding Children's Beliefs about and Behavioral Interactions with Anthropomorphic Toys

ERIC Educational Resources Information Center

Francis, Andrea; Mishra, Punya

2009-01-01

Interactive toys for children are becoming more popular for both play and educational purposes, yet an understanding of the dependent measures used to study such interactions has not yet been explored. This study takes advantage of the idea that robotic animals exhibit both living and pretend qualities, and are therefore ideal for studying…

Nature of Teacher-Students' Interaction in Electronic Learning and Traditional Courses of Higher Education--A Review

ERIC Educational Resources Information Center

Malik, Sufiana Khatoon; Khurshed, Fauzia

2011-01-01

Present paper explores differential teacher-student interaction in electronic learning (el) and in face to face traditional learning (tl) courses at higher education. After thorough study literature available and getting information from university teachers teaching el and tl courses about the nature of teacher-students interaction in both modes…

Self-Efficacy, Task Complexity and Task Performance: Exploring Interactions in Two Versions of Vocabulary Learning Tasks

ERIC Educational Resources Information Center

Wu, Xiaoli; Lowyck, Joost; Sercu, Lies; Elen, Jan

2012-01-01

The present study aimed for better understanding of the interactions between task complexity and students' self-efficacy beliefs and students' use of learning strategies, and finally their interacting effects on task performance. This investigation was carried out in the context of Chinese students learning English as a foreign language in a…

Determinants of Internet Use for Interactive Learning: An Exploratory Study

ERIC Educational Resources Information Center

Castaño, Jonatan; Duart, Josep M.; Sancho-Vinuesa, Teresa

2015-01-01

The use of the Internet in higher education teaching can facilitate the interactive learning process and thus improve educational outcomes. The aim of the study presented here is to explore which variables are linked to higher intensity of Internet-based interactive educational practices. The study is based on data obtained from an online survey…

Persistence Temperament Associated with Children Playing Math Games between Touch Panel and Embodied Interaction

ERIC Educational Resources Information Center

Jong, J-T.; Hong, J-C.; Yen, C-Y.

2013-01-01

The different designs of various interactive gaming controllers affect posture and muscle loading of the body. It is assumed that prolonged exposure to the interactive gaming controllers can affect the effectiveness in using the game for the purposes of learning. This study explores the differences in behavioural responses among students with…

CD-ROM Multimodal Affordances: Classroom Interaction Perspectives in the Malaysian English Literacy Hour

ERIC Educational Resources Information Center

Gardner, Sheena; Yaacob, Aizan

2009-01-01

CD-ROM affordances are explored in this article through participation in classroom interaction. CD-ROMs for shared reading of animated stories and language work were introduced to all Malaysian primary schools in 2003 for the Year 1 English Literacy Hour. We present classroom interaction extracts that show how the same CD-ROMs offer different…

Patterns of Kindergarten Children's Social Interaction with Peers in the Computer Area

ERIC Educational Resources Information Center

Lim, Eun Mee

2012-01-01

This study explored how young children interact with their peers in the computer area of a public kindergarten classroom. Children's social interaction, as defined in this study, is the action of giving and taking information that results in children's knowledge construction and cognitive development that can be accomplished through peer-to-peer…

Are We Allowed to Blink? Young Children's Leadership and Ownership while Mediating Interactions around Technologies

ERIC Educational Resources Information Center

Arnott, Lorna

2013-01-01

This article describes the formation of children's social interactions around technologies in preschools. This paper presents evidence from a study that explores how 3- to 5-year-old children construct their social interactions through the mediation of their peers while using technological resources. Utilising a systematic and iterative data…

Interaction of Dopamine Transporter (DAT1) Genotype and Maltreatment for ADHD: A Latent Class Analysis

ERIC Educational Resources Information Center

Li, James J.; Lee, Steve S.

2012-01-01

Background: Although the association of the dopamine transporter (DAT1) gene and attention-deficit/hyperactivity disorder (ADHD) has been widely studied, far less is known about its potential interaction with environmental risk factors. Given that maltreatment is a replicated risk factor for ADHD, we explored the interaction between DAT1 and…

Users' Interaction with World Wide Web Resources: An Exploratory Study Using a Holistic Approach.

ERIC Educational Resources Information Center

Wang, Peiling; Hawk, William B.; Tenopir, Carol

2000-01-01

Presents results of a study that explores factors of user-Web interaction in finding factual information, develops a conceptual framework for studying user-Web interaction, and applies a process-tracing method for conducting holistic user-Web studies. Describes measurement techniques and proposes a model consisting of the user, interface, and the…

Tree age and tree species shape positive and negative interactions in a montane meadow

Treesearch

Ryan D. Haugo; Charles Halpern

2010-01-01

Few studies have considered how interactions between woody and herbaceous species change in direction or magnitude over time or with traits of the dominant woody species. We used a chronosequence approach to explore these interactions in a montane meadow in which Pinus contorta Dougl. ex Loud. and Abies grandis (Dougl. ex. D....

Mentor-Mentee Interaction and Laboratory Social Environment: Do They Matter in Doctoral Students' Publication Productivity?

ERIC Educational Resources Information Center

Ynalvez, Marcus Antonius; Ynalvez, Ruby A.; Ramírez, Enrique

2017-01-01

We explored the social shaping of science at the micro-level reality of face-to-face interaction in one of the traditional places for scientific activities--the scientific lab. We specifically examined how doctoral students' perception of their: (i) interaction with doctoral mentors (MMI) and (ii) lab social environment (LSE) influenced…

Digging Deeper: Exploring the Relationship between Mentoring, Developmental Interactions, and Student Agency

ERIC Educational Resources Information Center

Griffin, Kimberly A.; Eury, Jennifer L.; Gaffney, Meghan E.

2015-01-01

While many cite the importance of having a mentor, focusing on the quality and nature of specific interactions between students and faculty can lead to better strategies promoting student agency. This chapter presents narratives from students who work with the same mentor, focusing on their interactions and how they shaped students' experiences…

E-Books Plus: Role of Interactive Visuals in Exploration of Mathematical Information and E-Learning

ERIC Educational Resources Information Center

Rowhani, Sonja; Sedig, Kamran

2005-01-01

E-books promise to become a widespread delivery mechanism for educational resources. However, current e-books do not take full advantage of the power of computing tools. In particular, interaction with the content is often reduced to navigation through the information. This article investigates how adding interactive visuals to an e-book…

Quality Standards Matter: A Comparative Case Study Examining Interactive Writing in the Preschool Setting

ERIC Educational Resources Information Center

Hall, Anna H.

2017-01-01

Interactive writing is a research-based early literacy strategy that has been found effective at increasing young children's oral language skills, alphabet knowledge, phonemic awareness, concepts of print, and early writing skills. This paper reports on a case study which explored the feasibility and fidelity of implementing interactive writing in…

Teacher-Student Interactions: Four Case Studies of Gender in Physical Education

ERIC Educational Resources Information Center

Davis, Kathryn; Nicaise, Virginia

2011-01-01

The aim of this study was to better understand gender interactions between teachers and students in high school physical education. Gender interactions were explored in relation to the theory of reflective practice. Interview data were examined as four case studies using individual and cross-case inductive analysis. Two common themes emerged: (a)…

Three Cultural Models of Teacher Interaction Valued by Mexican Students at a US High School

ERIC Educational Resources Information Center

Andrews, Micah

2016-01-01

Using students' interviews as data source, this study explores the interactional experiences of several Mexican students at a US high school in the Midwest with their teachers and discusses how three cultural models of teacher interaction valued by the students impact their affiliation, motivation, and engagement with school. Emphasis is given to…

Emotional Development and Construction of Teacher Identity: Narrative Interactions about the Pre-Service Teachers' Practicum Experiences

ERIC Educational Resources Information Center

Teng, Mark Feng

2017-01-01

Pre-service teacher identity research has directed limited attention to the construction and development of professional teacher identity through narrative interaction. An analysis of narrative interactions among pre-service teachers in the present study explored the ways in which they negotiated emotional flux in the process of training to become…

Social Presence and Interactivity in Online Courses: Enhancing the Online Learning Environment through Discussion and Writing

ERIC Educational Resources Information Center

Harrigan, Anne M.

2010-01-01

This study explored social presence and interactivity in an online undergraduate program designed for adult students. Although social presence and interactivity have been shown to be important contributors to student satisfaction, and therefore essential to student recruitment and retention in online programs, the ultimate goal for the examination…

CLASSROOM INTERACTION, PUPIL ACHIEVEMENT AND ADJUSTMENT IN TEAM TEACHING AS COMPARED WITH THE SELF-CONTAINED CLASSROOM.

ERIC Educational Resources Information Center

LAMBERT, PHILIP; AND OTHERS

EXPLORED ARE TEACHING AND LEARNING RELATIONSHIPS OR FORMS OF CLASSROOM INTERACTION IN THE TEAM TEACHING ARRANGEMENT, AND THE DIFFERENCES BETWEEN THESE AND TRADITIONAL CLASSROOM INTERACTION WITH RESPECT TO STUDENT ADJUSTMENT AND STUDENT ACHIEVEMENT. AN ATTEMPT WAS MADE TO IMPROVE THE SOPHISTICATION OF EDUCATIONAL RESEARCH INSTRUMENTS. A 2-YEAR TEAM…

Mining Learning Social Networks for Cooperative Learning with Appropriate Learning Partners in a Problem-Based Learning Environment

ERIC Educational Resources Information Center

Chen, Chih-Ming; Chang, Chia-Cheng

2014-01-01

Many studies have identified web-based cooperative learning as an increasingly popular educational paradigm with potential to increase learner satisfaction and interactions. However, peer-to-peer interaction often suffers barriers owing to a failure to explore useful social interaction information in web-based cooperative learning environments.…

Young Children's Self-Concepts: Associations with Child Temperament, Mothers' and Fathers' Parenting, and Triadic Family Interaction

ERIC Educational Resources Information Center

Brown, Geoffrey L.; Mangelsdorf, Sarah C.; Neff, Cynthia; Schoppe-Sullivan, Sarah J.; Frosch, Cynthia A.

2009-01-01

This study explored how children's self-concepts were related to child temperament, dyadic parenting behavior, and triadic family interaction. At age 3, child temperament, mothers' and fathers' parenting behavior, and triadic (mother, father, and child) family interaction were observed in the homes of 50 families. At age 4, children's…

Exploring the Interactions between Asian Culture (Confucianism) and Creativity

ERIC Educational Resources Information Center

Kim, Kyung Hee

2007-01-01

According to Csikszentmihalyi (1988), creativity is a very complex interaction among a person, a field, and a culture. In keeping with this approach, a look at Asian culture in relation to its impact on creativity is in order. While people may vary in their native capacity for creativity, it is in the individual's interaction with the macrocosm…

The Reliability and Validity of the Dominic Interactive: A Computerized Child Report Instrument for Mental Health Problems

ERIC Educational Resources Information Center

Kuijpers, Rowella C. W. M.; Otten, Roy; Krol, Nicole P. C. M.; Vermulst, Ad A.; Engels, Rutger C. M. E.

2013-01-01

Background: Children and youths' self-report of mental health problems is considered essential but complicated. Objective: This study examines the psychometric properties of the Dominic Interactive, a computerized DSM-IV based self-report questionnaire and explores informant correspondence. Methods: The Dominic Interactive was administered to 214…

Brought-Along Identities and the Dynamics of Ideology: Accomplishing Bivalent Stances in a Multilingual Interaction

ERIC Educational Resources Information Center

Williams, Ashley M.

2008-01-01

This paper examines how the interconnected aspects of the stance triangle (Du Bois 2007) allow speakers to tap into multiple ideological layers as they take a stance and reveal intra-ethnic group tensions. Using a detailed interaction analysis of a Chinese American family's multilingual interaction, the paper explores how such ideological dynamics…

Gender-Specific Perceptions of Four Dimensions of the Work/Family Interaction

ERIC Educational Resources Information Center

Innstrand, Siw Tone; Langballe, Ellen Melbye; Falkum, Erik; Espnes, Geir Arild; Aasland, Olaf Gjerlow

2009-01-01

The aim of this study was twofold. The first intention was to examine the factorial validity of a work/family interaction in terms of the direction of influence (work-to-family vs. family-to-work) and type of effect (conflict vs. facilitation). Second, gender differences along these four dimensions of work/family interaction were explored. Data…

Family Interaction in the Newborn Period: Some Findings, Some Observations, and Some Unresolved Issues.

ERIC Educational Resources Information Center

Parke, Ross D.

This paper presents two studies which explored the manner in which the father interacts with his newborn infant and compared paternal and maternal interaction patterns. In contrast to earlier studies, a direct observational approach was employed that permitted a detailed specification of father behaviors in the presence of the newborn. In the…

A tool for exploring space-time patterns: an animation user research.

PubMed

Ogao, Patrick J

2006-08-29

Ever since Dr. John Snow (1813-1854) used a case map to identify water well as the source of a cholera outbreak in London in the 1800s, the use of spatio-temporal maps have become vital tools in a wide range of disease mapping and control initiatives. The increasing use of spatio-temporal maps in these life-threatening sectors warrants that they are accurate, and easy to interpret to enable prompt decision making by health experts. Similar spatio-temporal maps are observed in urban growth and census mapping--all critical aspects a of a country's socio-economic development. In this paper, a user test research was carried out to determine the effectiveness of spatio-temporal maps (animation) in exploring geospatial structures encompassing disease, urban and census mapping. Three types of animation were used, namely; passive, interactive and inference-based animation, with the key differences between them being on the level of interactivity and complementary domain knowledge that each offers to the user. Passive animation maintains the view only status. The user has no control over its contents and dynamic variables. Interactive animation provides users with the basic media player controls, navigation and orientation tools. Inference-based animation incorporates these interactive capabilities together with a complementary automated intelligent view that alerts users to interesting patterns, trends or anomalies that may be inherent in the data sets. The test focussed on the role of animation passive and interactive capabilities in exploring space-time patterns by engaging test-subjects in thinking aloud evaluation protocol. The test subjects were selected from a geoinformatics (map reading, interpretation and analysis abilities) background. Every test-subject used each of the three types of animation and their performances for each session assessed. The results show that interactivity in animation is a preferred exploratory tool in identifying, interpreting and providing explanations about observed geospatial phenomena. Also, exploring geospatial data structures using animation is best achieved using provocative interactive tools such as was seen with the inference-based animation. The visual methods employed using the three types of animation are all related and together these patterns confirm the exploratory cognitive structure and processes for visualization tools. The generic types of animation as defined in this paper play a crucial role in facilitating the visualization of geospatial data. These animations can be created and their contents defined based on the user's presentational and exploratory needs. For highly explorative tasks, maintaining a link between the data sets and the animation is crucial to enabling a rich and effective knowledge discovery environment.

A tool for exploring space-time patterns : an animation user research

PubMed Central

Ogao, Patrick J

2006-01-01

Background Ever since Dr. John Snow (1813–1854) used a case map to identify water well as the source of a cholera outbreak in London in the 1800s, the use of spatio-temporal maps have become vital tools in a wide range of disease mapping and control initiatives. The increasing use of spatio-temporal maps in these life-threatening sectors warrants that they are accurate, and easy to interpret to enable prompt decision making by health experts. Similar spatio-temporal maps are observed in urban growth and census mapping – all critical aspects a of a country's socio-economic development. In this paper, a user test research was carried out to determine the effectiveness of spatio-temporal maps (animation) in exploring geospatial structures encompassing disease, urban and census mapping. Results Three types of animation were used, namely; passive, interactive and inference-based animation, with the key differences between them being on the level of interactivity and complementary domain knowledge that each offers to the user. Passive animation maintains the view only status. The user has no control over its contents and dynamic variables. Interactive animation provides users with the basic media player controls, navigation and orientation tools. Inference-based animation incorporates these interactive capabilities together with a complementary automated intelligent view that alerts users to interesting patterns, trends or anomalies that may be inherent in the data sets. The test focussed on the role of animation passive and interactive capabilities in exploring space-time patterns by engaging test-subjects in thinking aloud evaluation protocol. The test subjects were selected from a geoinformatics (map reading, interpretation and analysis abilities) background. Every test-subject used each of the three types of animation and their performances for each session assessed. The results show that interactivity in animation is a preferred exploratory tool in identifying, interpreting and providing explanations about observed geospatial phenomena. Also, exploring geospatial data structures using animation is best achieved using provocative interactive tools such as was seen with the inference-based animation. The visual methods employed using the three types of animation are all related and together these patterns confirm the exploratory cognitive structure and processes for visualization tools. Conclusion The generic types of animation as defined in this paper play a crucial role in facilitating the visualization of geospatial data. These animations can be created and their contents defined based on the user's presentational and exploratory needs. For highly explorative tasks, maintaining a link between the data sets and the animation is crucial to enabling a rich and effective knowledge discovery environment. PMID:16938138

Managing Educational Champions: Entrepreneurship in Schools

ERIC Educational Resources Information Center

Eyal, Ori; Yosef-Hassidim, Doron

2012-01-01

This study explores how educational champions--teachers who initiate unsolicited innovation--construct their entrepreneurial endeavors while interacting with principals' management styles and how that interaction influences the sustainability of teachers' initiatives. Through semistructured interviews (N = 71) and analysis anchored in grounded…

The effect of cultural interaction on cumulative cultural evolution.

PubMed

Nakahashi, Wataru

2014-07-07

Cultural transmission and cultural evolution are important for animals, especially for humans. I developed a new analytical model of cultural evolution, in which each newborn learns cultural traits from multiple individuals (exemplars) in parental generation, individually explores around learned cultural traits, judges the utility of known cultural traits, and adopts a mature cultural trait. Cultural evolutionary speed increases when individuals explore a wider range of cultural traits, accurately judge the skill level of cultural traits (strong direct bias), do not strongly conform to the population mean, increase the exploration range according to the variety of socially learned cultural traits (condition dependent exploration), and make smaller errors in social learning. Number of exemplars, population size, similarity of cultural traits between exemplars, and one-to-many transmission have little effect on cultural evolutionary speed. I also investigated how cultural interaction between two populations with different mean skill levels affects their cultural evolution. A population sometimes increases in skill level more if it encounters a less skilled population than if it does not encounter anyone. A less skilled population sometimes exceeds a more skilled population in skill level by cultural interaction between both populations. The appropriateness of this analytical method is confirmed by individual-based simulations. Copyright © 2014 Elsevier Ltd. All rights reserved.

Engaging Undergraduate Math Majors in Geoscience Research using Interactive Simulations and Computer Art

NASA Astrophysics Data System (ADS)

Matott, L. S.; Hymiak, B.; Reslink, C. F.; Baxter, C.; Aziz, S.

2012-12-01

As part of the NSF-sponsored 'URGE (Undergraduate Research Group Experiences) to Compute' program, Dr. Matott has been collaborating with talented Math majors to explore the design of cost-effective systems to safeguard groundwater supplies from contaminated sites. Such activity is aided by a combination of groundwater modeling, simulation-based optimization, and high-performance computing - disciplines largely unfamiliar to the students at the outset of the program. To help train and engage the students, a number of interactive and graphical software packages were utilized. Examples include: (1) a tutorial for exploring the behavior of evolutionary algorithms and other heuristic optimizers commonly used in simulation-based optimization; (2) an interactive groundwater modeling package for exploring alternative pump-and-treat containment scenarios at a contaminated site in Billings, Montana; (3) the R software package for visualizing various concepts related to subsurface hydrology; and (4) a job visualization tool for exploring the behavior of numerical experiments run on a large distributed computing cluster. Further engagement and excitement in the program was fostered by entering (and winning) a computer art competition run by the Coalition for Academic Scientific Computation (CASC). The winning submission visualizes an exhaustively mapped optimization cost surface and dramatically illustrates the phenomena of artificial minima - valley locations that correspond to designs whose costs are only partially optimal.

Intuitive Exploration of Volumetric Data Using Dynamic Galleries.

PubMed

Jönsson, Daniel; Falk, Martin; Ynnerman, Anders

2016-01-01

In this work we present a volume exploration method designed to be used by novice users and visitors to science centers and museums. The volumetric digitalization of artifacts in museums is of rapidly increasing interest as enhanced user experience through interactive data visualization can be achieved. This is, however, a challenging task since the vast majority of visitors are not familiar with the concepts commonly used in data exploration, such as mapping of visual properties from values in the data domain using transfer functions. Interacting in the data domain is an effective way to filter away undesired information but it is difficult to predict where the values lie in the spatial domain. In this work we make extensive use of dynamic previews instantly generated as the user explores the data domain. The previews allow the user to predict what effect changes in the data domain will have on the rendered image without being aware that visual parameters are set in the data domain. Each preview represents a subrange of the data domain where overview and details are given on demand through zooming and panning. The method has been designed with touch interfaces as the target platform for interaction. We provide a qualitative evaluation performed with visitors to a science center to show the utility of the approach.

Sonic Onyx: Case Study of an Interactive Artwork

NASA Astrophysics Data System (ADS)

Ahmed, Salah Uddin; Jaccheri, Letizia; M'kadmi, Samir

Software supported art projects are increasing in numbers in recent years as artists are exploring how computing can be used to create new forms of live art. Interactive sound installation is one kind of art in this genre. In this article we present the development process and functional description of Sonic Onyx, an interactive sound installation. The objective is to show, through the life cycle of Sonic Onyx, how a software dependent interactive artwork involves its users and raises issues related to its interaction and functionalities.

iELM—a web server to explore short linear motif-mediated interactions

PubMed Central

Weatheritt, Robert J.; Jehl, Peter; Dinkel, Holger; Gibson, Toby J.

2012-01-01

The recent expansion in our knowledge of protein–protein interactions (PPIs) has allowed the annotation and prediction of hundreds of thousands of interactions. However, the function of many of these interactions remains elusive. The interactions of Eukaryotic Linear Motif (iELM) web server provides a resource for predicting the function and positional interface for a subset of interactions mediated by short linear motifs (SLiMs). The iELM prediction algorithm is based on the annotated SLiM classes from the Eukaryotic Linear Motif (ELM) resource and allows users to explore both annotated and user-generated PPI networks for SLiM-mediated interactions. By incorporating the annotated information from the ELM resource, iELM provides functional details of PPIs. This can be used in proteomic analysis, for example, to infer whether an interaction promotes complex formation or degradation. Furthermore, details of the molecular interface of the SLiM-mediated interactions are also predicted. This information is displayed in a fully searchable table, as well as graphically with the modular architecture of the participating proteins extracted from the UniProt and Phospho.ELM resources. A network figure is also presented to aid the interpretation of results. The iELM server supports single protein queries as well as large-scale proteomic submissions and is freely available at http://i.elm.eu.org. PMID:22638578

How does leadership manifest in the patient-therapist interaction among physiotherapists in primary health care? A qualitative study.

PubMed

Rasmussen-Barr, Eva; Savage, Mairi; Von Knorring, Mia

2018-05-18

Health care is undergoing changes and this requires the participation and leadership of all health-care professions. While numerous studies have explored leadership competence among physicians and nurses, the physiotherapy profession has received but limited attention. The aim of this study was to explore how leadership manifests in the patient-therapist interaction among physiotherapists in primary health care and how the physiotherapists themselves relate their perception of leadership to their clinical practice. A qualitative study with semi-structured interviews was conducted with a purposive sample of 10 physiotherapists working in primary health care. The interviews were analyzed using inductive qualitative content analysis. Five themes were identified related to how leadership manifests in the patient-therapist interaction: (1) establishing resonant relationships; (2) engaging patients to build ownership; (3) drawing on authority; (4) building on professionalism; and (5) relating physiotherapists clinical practice to leadership. This study describes how leadership manifests in the patient-physiotherapist interaction. The findings can be used to empower physiotherapists in their clinical leadership and to give them confidence in taking on formal leadership roles, thus becoming active participants in improving health care. Future studies are needed to explore other aspects of leadership used in physiotherapy clinical practice.

Atomic structure considerations for the low-temperature opacity of Sn

DOE PAGES

Colgan, J.; Kilcrease, D. P.; Abdallah, J.; ...

2017-03-31

Here, we have begun a preliminary investigation into the opacity of Sn at low temperatures (< 50 eV). The emissivity and opacity of Sn is a crucial factor in determining the utility of Sn in EUV lithography, with numerous industrial implications. To this end, we have been exploring the accuracy of some approximations used in opacity models for the relevant ion stages of Sn (neutral through ~ 18 times ionized). We also find that the use of intermediate-coupling, as compared to full configuration-interaction, is not adequate to obtain accurate line positions of the important bound-bound transitions in Sn. One requiresmore » full configuration-interaction to properly describe the strong mixing between the various n=4 sub-shells that give rise to the Δn= 0 transitions that dominate the opacity spectrum at low temperatures. Furthermore, since calculations that include full configuration-interaction for large numbers of configurations quickly become computationally prohibitive, we have explored hybrid calculations, in which full configuration-interaction is retained for the most important transitions, while intermediate-coupling is employed for all other transitions. After extensive exploration of the atomic structure properties, local-thermodynamic-equilibrium (LTE) opacities are generated using the ATOMIC code at selected temperatures and densities and compared to experiment.« less

Atomic structure considerations for the low-temperature opacity of Sn

DOE Office of Scientific and Technical Information (OSTI.GOV)

Colgan, J.; Kilcrease, D. P.; Abdallah, J.

Here, we have begun a preliminary investigation into the opacity of Sn at low temperatures (< 50 eV). The emissivity and opacity of Sn is a crucial factor in determining the utility of Sn in EUV lithography, with numerous industrial implications. To this end, we have been exploring the accuracy of some approximations used in opacity models for the relevant ion stages of Sn (neutral through ~ 18 times ionized). We also find that the use of intermediate-coupling, as compared to full configuration-interaction, is not adequate to obtain accurate line positions of the important bound-bound transitions in Sn. One requiresmore » full configuration-interaction to properly describe the strong mixing between the various n=4 sub-shells that give rise to the Δn= 0 transitions that dominate the opacity spectrum at low temperatures. Furthermore, since calculations that include full configuration-interaction for large numbers of configurations quickly become computationally prohibitive, we have explored hybrid calculations, in which full configuration-interaction is retained for the most important transitions, while intermediate-coupling is employed for all other transitions. After extensive exploration of the atomic structure properties, local-thermodynamic-equilibrium (LTE) opacities are generated using the ATOMIC code at selected temperatures and densities and compared to experiment.« less

Human eye haptics-based multimedia.

PubMed

Velandia, David; Uribe-Quevedo, Alvaro; Perez-Gutierrez, Byron

2014-01-01

Immersive and interactive multimedia applications offer complementary study tools in anatomy as users can explore 3D models while obtaining information about the organ, tissue or part being explored. Haptics increases the sense of interaction with virtual objects improving user experience in a more realistic manner. Common eye studying tools are books, illustrations, assembly models, and more recently these are being complemented with mobile apps whose 3D capabilities, computing power and customers are increasing. The goal of this project is to develop a complementary eye anatomy and pathology study tool using deformable models within a multimedia application, offering the students the opportunity for exploring the eye from up close and within with relevant information. Validation of the tool provided feedback on the potential of the development, along with suggestions on improving haptic feedback and navigation.

Infants born preterm demonstrate impaired object exploration behaviors throughout infancy and toddlerhood.

PubMed

Lobo, Michele A; Kokkoni, Elena; Cunha, Andrea Baraldi; Galloway, James Cole

2015-01-01

Object exploration behaviors form the foundation for future global development, but little is known about how these behaviors are exhibited by infants born preterm. The study objective was to longitudinally compare a comprehensive set of object exploration behaviors in infants born preterm and infants born full-term from infancy into toddlerhood. Twenty-two infants born full-term and 28 infants born preterm were monitored as they interacted with objects throughout their first 2 years. Infants were provided up to 30 seconds to interact with each of 7 objects across 9 visits. Experimenters coded videos of infants' behaviors. Growth modeling and t tests were used to compare how much infants exhibited behaviors and how well they matched their behaviors to the properties of objects. Infants born preterm explored objects less in the first 6 months, exhibited less visual-haptic multimodal exploration, displayed reduced variability of exploratory behavior in a manner that reflected severity of risk, and were less able to match their behaviors to the properties of objects in a manner that reflected severity of risk. Infants born preterm with significant brain injury also had impaired bimanual abilities. There was a limited sample of infants born preterm with significant brain injury. Infants born preterm have impaired abilities to interact with objects even in the first months of life. This impairment likely limits the knowledge they acquire about objects and about how they can act on them; this limited knowledge may, in turn, impair their early learning abilities. These results highlight the need for assessment and intervention tools specific for object exploration in young infants. © 2015 American Physical Therapy Association.

Infants Born Preterm Demonstrate Impaired Object Exploration Behaviors Throughout Infancy and Toddlerhood

PubMed Central

Kokkoni, Elena; Cunha, Andrea Baraldi; Galloway, James Cole

2015-01-01

Background Object exploration behaviors form the foundation for future global development, but little is known about how these behaviors are exhibited by infants born preterm. Objective The study objective was to longitudinally compare a comprehensive set of object exploration behaviors in infants born preterm and infants born full-term from infancy into toddlerhood. Design Twenty-two infants born full-term and 28 infants born preterm were monitored as they interacted with objects throughout their first 2 years. Methods Infants were provided up to 30 seconds to interact with each of 7 objects across 9 visits. Experimenters coded videos of infants' behaviors. Growth modeling and t tests were used to compare how much infants exhibited behaviors and how well they matched their behaviors to the properties of objects. Results Infants born preterm explored objects less in the first 6 months, exhibited less visual-haptic multimodal exploration, displayed reduced variability of exploratory behavior in a manner that reflected severity of risk, and were less able to match their behaviors to the properties of objects in a manner that reflected severity of risk. Infants born preterm with significant brain injury also had impaired bimanual abilities. Limitations There was a limited sample of infants born preterm with significant brain injury. Conclusions Infants born preterm have impaired abilities to interact with objects even in the first months of life. This impairment likely limits the knowledge they acquire about objects and about how they can act on them; this limited knowledge may, in turn, impair their early learning abilities. These results highlight the need for assessment and intervention tools specific for object exploration in young infants. PMID:25169919

Toward a systematic exploration of nano-bio interactions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bai, Xue; Liu, Fang; Liu, Yin

Many studies of nanomaterials make non-systematic alterations of nanoparticle physicochemical properties. Given the immense size of the property space for nanomaterials, such approaches are not very useful in elucidating fundamental relationships between inherent physicochemical properties of these materials and their interactions with, and effects on, biological systems. Data driven artificial intelligence methods such as machine learning algorithms have proven highly effective in generating models with good predictivity and some degree of interpretability. They can provide a viable method of reducing or eliminating animal testing. However, careful experimental design with the modelling of the results in mind is a proven andmore » efficient way of exploring large materials spaces. This approach, coupled with high speed automated experimental synthesis and characterization technologies now appearing, is the fastest route to developing models that regulatory bodies may find useful. We advocate greatly increased focus on systematic modification of physicochemical properties of nanoparticles combined with comprehensive biological evaluation and computational analysis. This is essential to obtain better mechanistic understanding of nano-bio interactions, and to derive quantitatively predictive and robust models for the properties of nanomaterials that have useful domains of applicability. - Highlights: • Nanomaterials studies make non-systematic alterations to nanoparticle properties. • Vast nanomaterials property spaces require systematic studies of nano-bio interactions. • Experimental design and modelling are efficient ways of exploring materials spaces. • We advocate systematic modification and computational analysis to probe nano-bio interactions.« less

Measuring social attention and motivation in autism spectrum disorder using eye-tracking: Stimulus type matters.

PubMed

Chevallier, Coralie; Parish-Morris, Julia; McVey, Alana; Rump, Keiran M; Sasson, Noah J; Herrington, John D; Schultz, Robert T

2015-10-01

Autism Spectrum Disorder (ASD) is characterized by social impairments that have been related to deficits in social attention, including diminished gaze to faces. Eye-tracking studies are commonly used to examine social attention and social motivation in ASD, but they vary in sensitivity. In this study, we hypothesized that the ecological nature of the social stimuli would affect participants' social attention, with gaze behavior during more naturalistic scenes being most predictive of ASD vs. typical development. Eighty-one children with and without ASD participated in three eye-tracking tasks that differed in the ecological relevance of the social stimuli. In the "Static Visual Exploration" task, static images of objects and people were presented; in the "Dynamic Visual Exploration" task, video clips of individual faces and objects were presented side-by-side; in the "Interactive Visual Exploration" task, video clips of children playing with objects in a naturalistic context were presented. Our analyses uncovered a three-way interaction between Task, Social vs. Object Stimuli, and Diagnosis. This interaction was driven by group differences on one task only-the Interactive task. Bayesian analyses confirmed that the other two tasks were insensitive to group membership. In addition, receiver operating characteristic analyses demonstrated that, unlike the other two tasks, the Interactive task had significant classification power. The ecological relevance of social stimuli is an important factor to consider for eye-tracking studies aiming to measure social attention and motivation in ASD. © 2015 International Society for Autism Research, Wiley Periodicals, Inc.

NASA launches dual Dynamics Explorer spacecraft

NASA Technical Reports Server (NTRS)

1981-01-01

A Delta launch vehicle was used to insert Dynamics Explorer A into a highly elliptical polar orbit, ranging from 675 to 24,945 km, and Dynamics Explorer B satellite into a low polar orbit, ranging from 306 to 1,300 km. The two spacecraft are designed to provide specific knowledge about the interaction of energy, electric currents, electric fields, and plasmas between the magnetosphere, the ionosphere, and the atmosphere.

ActiviTree: interactive visual exploration of sequences in event-based data using graph similarity.

PubMed

Vrotsou, Katerina; Johansson, Jimmy; Cooper, Matthew

2009-01-01

The identification of significant sequences in large and complex event-based temporal data is a challenging problem with applications in many areas of today's information intensive society. Pure visual representations can be used for the analysis, but are constrained to small data sets. Algorithmic search mechanisms used for larger data sets become expensive as the data size increases and typically focus on frequency of occurrence to reduce the computational complexity, often overlooking important infrequent sequences and outliers. In this paper we introduce an interactive visual data mining approach based on an adaptation of techniques developed for web searching, combined with an intuitive visual interface, to facilitate user-centred exploration of the data and identification of sequences significant to that user. The search algorithm used in the exploration executes in negligible time, even for large data, and so no pre-processing of the selected data is required, making this a completely interactive experience for the user. Our particular application area is social science diary data but the technique is applicable across many other disciplines.

YouDash3D: exploring stereoscopic 3D gaming for 3D movie theaters

NASA Astrophysics Data System (ADS)

Schild, Jonas; Seele, Sven; Masuch, Maic

2012-03-01

Along with the success of the digitally revived stereoscopic cinema, events beyond 3D movies become attractive for movie theater operators, i.e. interactive 3D games. In this paper, we present a case that explores possible challenges and solutions for interactive 3D games to be played by a movie theater audience. We analyze the setting and showcase current issues related to lighting and interaction. Our second focus is to provide gameplay mechanics that make special use of stereoscopy, especially depth-based game design. Based on these results, we present YouDash3D, a game prototype that explores public stereoscopic gameplay in a reduced kiosk setup. It features live 3D HD video stream of a professional stereo camera rig rendered in a real-time game scene. We use the effect to place the stereoscopic effigies of players into the digital game. The game showcases how stereoscopic vision can provide for a novel depth-based game mechanic. Projected trigger zones and distributed clusters of the audience video allow for easy adaptation to larger audiences and 3D movie theater gaming.

Virtual reality and planetary exploration

NASA Technical Reports Server (NTRS)

Mcgreevy, Michael W.

1992-01-01

NASA-Ames is intensively developing virtual-reality (VR) capabilities that can extend and augment computer-generated and remote spatial environments. VR is envisioned not only as a basis for improving human/machine interactions involved in planetary exploration, but also as a medium for the more widespread sharing of the experience of exploration, thereby broadening the support-base for the lunar and planetary-exploration endeavors. Imagery representative of Mars are being gathered for VR presentation at such terrestrial sites as Antarctica and Death Valley.

Rapid and sensitive MRM-based mass spectrometry approach for systematically exploring ganglioside-protein interactions.

PubMed

Tian, Ruijun; Jin, Jing; Taylor, Lorne; Larsen, Brett; Quaggin, Susan E; Pawson, Tony

2013-04-01

Gangliosides are ubiquitous components of cell membranes. Their interactions with bacterial toxins and membrane-associated proteins (e.g. receptor tyrosine kinases) have important roles in the regulation of multiple cellular functions. Currently, an effective approach for measuring ganglioside-protein interactions especially in a large-scale fashion is largely missing. To this end, we report a facile MS-based approach to explore gangliosides extracted from cells and measure their interactions with protein of interest globally. We optimized a two-step protocol for extracting total gangliosides from cells within 2 h. Easy-to-use magnetic beads conjugated with a protein of interest were used to capture interacting gangliosides. To measure ganglioside-protein interaction on a global scale, we applied a high-sensitive LC-MS system, containing hydrophilic interaction LC separation and multiple reaction monitoring-based MS for ganglioside detection. Sensitivity for ganglioside GM1 is below 100 pg, and the whole analysis can be done in 20 min with isocratic elution. To measure ganglioside interactions with soluble vascular endothelial growth factor receptor 1 (sFlt1), we extracted and readily detected 36 species of gangliosides from perivascular retinal pigment epithelium cells across eight different classes. Twenty-three ganglioside species have significant interactions with sFlt1 as compared with IgG control based on p value cutoff <0.05. These results show that the described method provides a rapid and high-sensitive approach for systematically measuring ganglioside-protein interactions. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Discovery Learning, Representation, and Explanation within a Computer-Based Simulation: Finding the Right Mix

ERIC Educational Resources Information Center

Rieber, Lloyd P.; Tzeng, Shyh-Chii; Tribble, Kelly

2004-01-01

The purpose of this research was to explore how adult users interact and learn during an interactive computer-based simulation supplemented with brief multimedia explanations of the content. A total of 52 college students interacted with a computer-based simulation of Newton's laws of motion in which they had control over the motion of a simple…

Developing the Understanding of the Role of Interpersonal Interaction in Early Literacy Development: A Case Study of a Thai Public Preschool

ERIC Educational Resources Information Center

Klibthong, Sunanta

2012-01-01

This study focuses on the role of interpersonal interaction in early literacy development in one public preschool school in Bangkok, Thailand. Specifically, it explores and analyses the nature of interpersonal interaction and collaborative activities the teachers employ in teaching literacy to children. The study involves observation of 82…

Facilitating Engaged Learning in the Interaction Age Taking a Pedagogically-Disciplined Approach to Innovation with Emergent Technologies

ERIC Educational Resources Information Center

Brill, Jennifer M.; Park, Yeonjeong

2008-01-01

The purposes of this paper are to explore emerging technologies, engaged learning, and features and students of the Interaction Age and to identify connections across these three realms for future research and practice. We begin by highlighting those elements of the Interaction Age that suggest a shift in the affordances and applications of…

Interactive eLearning - a safe place to practice.

PubMed

Einarson, Elisabeth; Moen, Anne; Kolberg, Ragnhild; Flingtorp, Gry; Linnerud, Eva

2009-01-01

Interactive web-based learning environment offers refreshing opportunities to create innovative solutions to explore and exploit informatics support on-the-job training. We report from a study where a hospital is created a interactive eLearning resource. The modules are creating a safe place to practice - to be used for introduction to the work and preparation for certification or re-certification of competencies.

Interracial Contact on College Campuses: Comparing and Contrasting Predictors of Cross-Racial Interaction and Interracial Friendship

ERIC Educational Resources Information Center

Bowman, Nicholas A.; Park, Julie J.

2014-01-01

Research on diversity in higher education has evolved to consider the nature of interracial contact and campus climate as well as the factors that may foster meaningful interactions. While some studies have explored predictors of cross-racial interaction (CRI) and interracial friendship (IRF), it remains unclear whether and how the same precollege…

Exploring the Rhetorical Use of Interactional Metadiscourse: A Comparison of Letters to Shareholders of American and Chinese Financial Companies

ERIC Educational Resources Information Center

Xiaoqin, Liu

2017-01-01

By taking Hyland and Tse's (2004) interactional metadiscourse model, this study attempts to compare the incidence of the interactional metadiscourse markers in letters to shareholders of American and Chinese companies in the financial industry and their rhetorical functions. This study makes American corpus of 41 letters and Chinese corpus of 37…

Choosing to Interact: Exploring the Relationship between Learner Personality, Attitudes, and Tutorial Dialogue Participation

ERIC Educational Resources Information Center

Ezen-Can, Aysu; Boyer, Kristy Elizabeth

2015-01-01

The tremendous effectiveness of intelligent tutoring systems is due in large part to their interactivity. However, when learners are free to choose the extent to which they interact with a tutoring system, not all learners do so actively. This paper examines a study with a natural language tutorial dialogue system for computer science, in which…

"Just Wait Then and See What He Does": A Speech Act Analysis of Healthcare Professionals' Interaction Coaching with Parents of Children with Autism Spectrum Disorders

ERIC Educational Resources Information Center

McKnight, Lindsay M.; O'Malley-Keighran, Mary-Pat; Carroll, Clare

2016-01-01

Background: There is evidence indicating that parent training programmes including interaction coaching of parents of children with autism spectrum disorders (ASD) can increase parental responsiveness, promote language development and social interaction skills in children with ASD. However, there is a lack of research exploring precisely how…

Using the Artistic Pedagogical Technology of Photovoice to Promote Interaction in the Online Post-Secondary Classroom: The Students' Perspective

ERIC Educational Resources Information Center

Edwards, Margaret; Perry, Beth; Janzen, Katherine; Menzies, Cynthia

2012-01-01

This study explores the effect of the artistic pedagogical technology (APT) called photovoice (PV) on interaction in the online post-secondary classroom. More specifically, this paper focuses on students' perspectives regarding the effect of PV on student to student and student to instructor interactions in online courses. Artistic pedagogical…

Interactivity in the Teaching and Learning of Foreign Languages: What It Means for Resourcing and Delivery of Online and Blended Programmes

ERIC Educational Resources Information Center

Tudini, Vincenza

2018-01-01

University students who enrol in foreign language (FL) programmes are motivated by various needs, but in particular the need to achieve communicative fluency, which generally requires interaction with others. This study therefore explores the notion of 'interactivity,' as conceptualised in second language learning theories and how it might be…

Interactivity and ICT in the Primary School: Categories of Learner Interactions with and without ICT

ERIC Educational Resources Information Center

Beauchamp, Gary

2011-01-01

This article will analyse primary teachers' views on the role of information and communications technology (ICT) in the broader context of pedagogy in the classroom. It uses data collected from primary teacher interviews in the early stages of a funded research project (which analysed interactivity and ICT in learning and teaching) to explore and…

Do Mothers' and Fathers' Authoritative and Authoritarian Parenting Interact? An Exploration on Schooling Aspects with a Singapore Adolescent Sample

ERIC Educational Resources Information Center

Sim, Tick N.; Chin, Jeffery E. H.

2014-01-01

Our study sought mainly to examine interactions between mothers' and fathers' authoritative and authoritarian parenting. A total of 284 adolescents (mean age 13.5) from 2 Singapore schools contributed self-report data on their parents' parenting and various schooling aspects. Prior to testing for interactions, adolescents with two authoritative…

Gene-Environment Interactions across Development: Exploring DRD2 Genotype and Prenatal Smoking Effects on Self-Regulation

ERIC Educational Resources Information Center

Wiebe, Sandra A.; Espy, Kimberly Andrews; Stopp, Christian; Respass, Jennifer; Stewart, Peter; Jameson, Travis R.; Gilbert, David G.; Huggenvik, Jodi I.

2009-01-01

Genetic factors dynamically interact with both pre- and postnatal environmental influences to shape development. Considerable attention has been devoted to gene-environment interactions (G x E) on important outcomes (A. Caspi & T. E. Moffitt, 2006). It is also important to consider the possibility that these G x E effects may vary across…

An Investigation into the Community of Inquiry Model in the Malaysian ESL Learners' Context

ERIC Educational Resources Information Center

Annamalai, Nagaletchimee

2017-01-01

Purpose: This study aims to explore how the Community of Inquiry (CoI) model (2000) is used to categorize students' and teachers' interactions in an asynchronous discussion and how these interactions are able to help students add quality to their narrative writing. Design/methodology/approach: The interactions were categorized based on teaching,…

Locating Cognition in Second Language Interaction and Learning: Inside the Skull or in Public View?

ERIC Educational Resources Information Center

Kasper, Gabriele

2009-01-01

A key question in the debate on conversation analysis as an approach to SLA concerns the role of cognition in interaction and learning. Where is cognition located, and how is understanding in interaction achieved? For an empirically grounded answer, I will explore the procedural apparatus that sustains socially shared cognition. Following a brief…

Designing Smart Artifacts for Adaptive Mediation of Social Viscosity: Triadic Actor-Network Enactments as a Basis for Interaction Design

ERIC Educational Resources Information Center

Salamanca, Juan

2012-01-01

With the advent of ubiquitous computing, interaction design has broadened its object of inquiry into how smart computational artifacts inconspicuously act in people's everyday lives. Although user-centered design approaches remains useful for exploring how people cope with interactive systems, they cannot explain how this new breed of…

Design of interactive health drama built on social realism.

PubMed

Graspemo, Gabriella; Hassling, Linda; Nordfeldt, Sam; Eriksson, Hendrik; Timpka, Toomas

2004-01-01

There are many psychosocial aspects of chronic diseases, such as diabetes. Educational multimedia can support patients with chronic diseases and their families by communicating narratives based on social realism. The production of such socio-realistic interactive health dramas requires systematic methods, especially for the identification of significant stories. The aim of this study is to explore the use of self-documentary video in the design of an Interactive Health Drama environment to support diabetic adolescents and their families. In particular, the potential of the self-documentary video for story development in combination with qualitative interviews were explored. The proposed approach, when further developed, is intended to enable all types of chronic disease patients to work with their specific psychosocial problems in a supportive and stimulating environment adapted to their personality and preferences.

Games of life and death: antibiotic resistance and production through the lens of evolutionary game theory.

PubMed

Conlin, Peter L; Chandler, Josephine R; Kerr, Benjamin

2014-10-01

In this review, we demonstrate how game theory can be a useful first step in modeling and understanding interactions among bacteria that produce and resist antibiotics. We introduce the basic features of evolutionary game theory and explore model microbial systems that correspond to some classical games. Each game discussed defines a different category of social interaction with different resulting population dynamics (exclusion, coexistence, bistability, cycling). We then explore how the framework can be extended to incorporate some of the complexity of natural microbial communities. Overall, the game theoretical perspective helps to guide our expectations about the evolution of some forms of antibiotic resistance and production because it makes clear the precise nature of social interaction in this context. Copyright © 2014 Elsevier Ltd. All rights reserved.

Effect of health education on patients' beliefs about glaucoma and compliance.

PubMed

Rendell, J

2000-01-01

A pretest-posttest control group experimental design (n = 100) was used to determine the effectiveness of an interactive patient education program compared with a didactic approach for persons with primary open angle glaucoma at a major specialist eye hospital in England. This study used a questionnaire with a knowledge test to explore patients' glaucoma knowledge, a series of vignettes to explore understanding of compliance and health motivation, and health locus of control scales to assess the effect of these variables. The improved posttest results (P = .000) suggest that patients benefit from education programs and that the ophthalmic nurse is an effective patient teacher. The interactive program has no statistically significant difference from the didactic presentation. Other types of interactive programs may prove to be more beneficial.

Analysis of hand contact areas and interaction capabilities during manipulation and exploration.

PubMed

Gonzalez, Franck; Gosselin, Florian; Bachta, Wael

2014-01-01

Manual human-computer interfaces for virtual reality are designed to allow an operator interacting with a computer simulation as naturally as possible. Dexterous haptic interfaces are the best suited for this goal. They give intuitive and efficient control on the environment with haptic and tactile feedback. This paper is aimed at helping in the choice of the interaction areas to be taken into account in the design of such interfaces. The literature dealing with hand interactions is first reviewed in order to point out the contact areas involved in exploration and manipulation tasks. Their frequencies of use are then extracted from existing recordings. The results are gathered in an original graphical interaction map allowing for a simple visualization of the way the hand is used, and compared with a map of mechanoreceptors densities. Then an interaction tree, mapping the relative amount of actions made available through the use of a given contact area, is built and correlated with the losses of hand function induced by amputations. A rating of some existing haptic interfaces and guidelines for their design are finally achieved to illustrate a possible use of the developed graphical tools.

Physiology of Mechanotransduction: How Do Muscle and Bone "Talk" to One Another?

PubMed

Isaacson, Janalee; Brotto, Marco

2014-06-01

The complexity of cell interactions with their microenvironment and their ability to communicate at the autocrine, paracrine, and endocrine levels has gradually but significantly evolved in the last three decades. The musculoskeletal system has been historically recognized to be governed by a relationship of proximity and function, chiefly dictated by mechanical forces and the work of gravity itself. In this review article, we first provide a historical overview of the biomechanical theory of bone- muscle interactions. Next, we expand to detail the significant evolution in our understanding of the function of bones and muscles as secretory organs. Then, we review and discuss new evidence in support of a biochemical interaction between these two tissues. We then propose that these two models of interaction are complementary and intertwined providing for a new frontier for the investigation of how bone-muscle cross talk could be fully explored for the targeting of new therapies for musculoskeletal diseases, particularly the twin conditions of aging, osteoporosis and sarcopenia. In the last section, we explore the bone-muscle cross talk in the context of their interactions with other tissues and the global impact of these multi-tissue interactions on chronic diseases.

Physiology of Mechanotransduction: How Do Muscle and Bone “Talk” to One Another?

PubMed Central

Isaacson, Janalee

2015-01-01

The complexity of cell interactions with their microenvironment and their ability to communicate at the autocrine, paracrine, and endocrine levels has gradually but significantly evolved in the last three decades. The musculoskeletal system has been historically recognized to be governed by a relationship of proximity and function, chiefly dictated by mechanical forces and the work of gravity itself. In this review article, we first provide a historical overview of the biomechanical theory of bone– muscle interactions. Next, we expand to detail the significant evolution in our understanding of the function of bones and muscles as secretory organs. Then, we review and discuss new evidence in support of a biochemical interaction between these two tissues. We then propose that these two models of interaction are complementary and intertwined providing for a new frontier for the investigation of how bone–muscle cross talk could be fully explored for the targeting of new therapies for musculoskeletal diseases, particularly the twin conditions of aging, osteoporosis and sarcopenia. In the last section, we explore the bone–muscle cross talk in the context of their interactions with other tissues and the global impact of these multi-tissue interactions on chronic diseases. PMID:25838800

The E-music box: an empirical method for exploring the universal capacity for musical production and for social interaction through music.

PubMed

Novembre, Giacomo; Varlet, Manuel; Muawiyath, Shujau; Stevens, Catherine J; Keller, Peter E

2015-11-01

Humans are assumed to have a natural-universal-predisposition for making music and for musical interaction. Research in this domain is, however, typically conducted with musically trained individuals, and therefore confounded with expertise. Here, we present a rediscovered and updated invention-the E-music box-that we establish as an empirical method to investigate musical production and interaction in everyone. The E-music box transforms rotatory cyclical movements into pre-programmable digital musical output, with tempo varying according to rotation speed. The user's movements are coded as continuous oscillatory data, which can be analysed using linear or nonlinear analytical tools. We conducted a proof-of-principle experiment to demonstrate that, using this method, pairs of non-musically trained individuals can interact according to conventional musical practices (leader/follower roles and lower-pitch dominance). The results suggest that the E-music box brings 'active' and 'interactive' musical capacities within everyone's reach. We discuss the potential of this method for exploring the universal predisposition for music making and interaction in developmental and cross-cultural contexts, and for neurologic musical therapy and rehabilitation.

Quantum chemical exploration of the intramolecular hydrogen bond interaction in 2-thiazol-2-yl-phenol and 2-benzothiazol-2-yl-phenol in the context of excited-state intramolecular proton transfer: A focus on the covalency in hydrogen bond

NASA Astrophysics Data System (ADS)

Paul, Bijan Kumar; Ganguly, Aniruddha; Guchhait, Nikhil

2014-10-01

The present work demonstrates a computational exploration of the intramolecular H-bond (IMHB) interaction in two model heterocyclic compounds - 2-thiazol-2-yl-phenol (2T2YP) and 2-benzothiazol-2-yl-phenol (2B2YP) by meticulous application of various quantum chemical tools. Major emphasis is rendered on the analysis of IMHB interaction by calculation of electron density ρ(r) and Laplacian ∇2ρ(r) at the bond critical point using the Atoms-In-Molecule methodology. Topological features based on ρ(r) suggest that at equilibrium geometry the IMHB interaction develops certain characteristics typical of a covalent interaction. The interplay between aromaticity and Resonance-Assisted H-Bond (RAHB) has also been discussed using both geometrical and magnetic criteria. The occurrence of IMHB interaction in 2T2YP and 2B2YP has also been criticized under the provision of the Natural Bond Orbital (NBO) analysis. The ESIPT phenomenon in the molecular systems is also critically addressed on the lexicon of potential energy surface (PES) analysis.

Exploring Nonconvex, Crossed and Degenerate Polygons

ERIC Educational Resources Information Center

Contreras, Jose N.

2004-01-01

An exploration of nonconvex, crossed, and degenerate polygons (NCCDPs) are described with the help of examples with pedagogical tips and recommendations that are found useful when teaching the mathematical process of extending geometric patterns to NCCDPs. The study concludes that investigating such extensions with interactive geometry software…

Exploring Intercultural Competence in a Victorian Novel

ERIC Educational Resources Information Center

Malgesini, Frank

2012-01-01

Although the characters speak English, Anne Bronte's "The Tenant of Wildfell Hall" explores interactions among representatives of different speech communities. The protagonist, Helen Graham, moves through communities differing enough from hers to create misunderstandings. Her difficulties can be clarified through Hymes' model of the speech…

Discovery through maps: Exploring real-world applications of ecosystem services

EPA Science Inventory

Background/Question/Methods U.S. EPA’s EnviroAtlas provides a collection of interactive tools and resources for exploring ecosystem goods and services. The purpose of EnviroAtlas is to provide better access to consistently derived ecosystems and socio-economic data to facil...

Earth Trek...Explore Your Environment.

ERIC Educational Resources Information Center

Environmental Protection Agency, Washington, DC. Office of Public Affairs.

This booklet for children emphasizes the exploration and protection of the environment. An introduction discusses the interaction between humankind and the environment, emphasizing that the earth is a closed system. Chapter 1, "Mission: Protect the Water," addresses human dependence on water, water pollution, and water treatment. Chapter…

Modulation of the Conformational Dynamics of Apo-Adenylate Kinase through a π-Cation Interaction.

PubMed

Halder, Ritaban; Manna, Rabindra Nath; Chakraborty, Sandipan; Jana, Biman

2017-06-15

Large-scale conformational transition from open to closed state of adenylate kinase (ADK) is essential for its catalytic cycle. Apo-ADK undergoes conformational transition in a way that closely resembles an open-to-closed conformational transition. Here, equilibrium simulations, free-energy simulations, and quantum mechanics/molecular mechanics (QM/MM) calculations in combination with several bioinformatics approaches have been used to explore the molecular origin of this conformational transition in apo-ADK. In addition to its conventional open state, Escherichia coli apo-ADK adopts conformations that resemble a closed-like intermediate, the "half-open-half-closed" (HOHC) state, and a π-cation interaction can account for the stability of this HOHC state. Energetics and the electronic properties of this π-cation interaction have been explored using QM/MM calculations. Upon rescinding the π-cation interaction, the conformational landscape of the apo-ADK changes completely. The apo-ADK population is shifted completely toward the open state. This π-cation interaction is highly conserved in bacterial ADK; the cationic guanidinium moiety of a conserved ARG interacts with the delocalized π-electron cloud of either PHE or TYR. Interestingly, this study demonstrates the modulation of a principal protein dynamics by a conserved specific π-cation interaction across different organisms.

Exploring the Complexities of Children's Inquiries in Science: Knowledge Production Through Participatory Practices

NASA Astrophysics Data System (ADS)

Siry, Christina

2013-12-01

Beginning with the assumption that young children are capable of producing unprecedented knowledges about science phenomena, this paper explores the complexities of children's inquiries within open-ended investigations. I ask two central questions: (1) how can we (teachers, researchers, and children themselves) use and build upon children's explorations in science in practice? and (2) what pedagogical approaches can position children as experts on their experiences to facilitate children's sense of ownership in the process of learning science? Six vignettes from a Kindergarten classroom are analyzed to elaborate the central claim of this work, which is that when children are engaged in collaborative open-ended activities, science emerges from their interactions. Open-ended structures allowed for teachers and children to facilitate further investigations collaboratively, and participatory structures mediated children's representations and explanations of their investigations. Evidence of children's interactions is used to illustrate the complexities of children's explorations, and pedagogical approaches that create the spaces for children to create knowledge are highlighted.

Region Evolution eXplorer - A tool for discovering evolution trends in ontology regions.

PubMed

Christen, Victor; Hartung, Michael; Groß, Anika

2015-01-01

A large number of life science ontologies has been developed to support different application scenarios such as gene annotation or functional analysis. The continuous accumulation of new insights and knowledge affects specific portions in ontologies and thus leads to their adaptation. Therefore, it is valuable to study which ontology parts have been extensively modified or remained unchanged. Users can monitor the evolution of an ontology to improve its further development or apply the knowledge in their applications. Here we present REX (Region Evolution eXplorer) a web-based system for exploring the evolution of ontology parts (regions). REX provides an analysis platform for currently about 1,000 versions of 16 well-known life science ontologies. Interactive workflows allow an explorative analysis of changing ontology regions and can be used to study evolution trends for long-term periods. REX is a web application providing an interactive and user-friendly interface to identify (un)stable regions in large life science ontologies. It is available at http://www.izbi.de/rex.

"Musical co-creation"? Exploring health-promoting potentials on the use of musical and interactive tangibles for families with children with disabilities.

PubMed

Stensæth, Karette

2013-08-07

The point of departure in this text is the ongoing qualitative interdisciplinary research project RHYME (www.RHYME.no), which addresses the lack of health-promoting interactive and musical Information and Communications Technology (ICT) for families with children with severe disabilities. The project explores a new treatment paradigm based on collaborative, tangible, interactive net-based musical "smart things" with multimedia capabilities. The goal in RHYME is twofold: (1) to reduce isolation and passivity, and (2) to promote health and well-being. Co-creation is suggested as a possible path to achieving these goals, by evoking feelings, for example, or accommodating the needs to act and to create social relations; co-creation also motivates users to communicate and collaborate within (new) social relations. This article engages co-creation by incorporating aspects connected to interaction design and the field of music and health. Empirical observations will be referred to. The research question is as follows: What might co-creation imply for families of children with disabilities when musical and interactive tangibles are used as health-promoting implements?

“Musical co-creation”? Exploring health-promoting potentials on the use of musical and interactive tangibles for families with children with disabilities

PubMed Central

2013-01-01

The point of departure in this text is the ongoing qualitative interdisciplinary research project RHYME (www.RHYME.no), which addresses the lack of health-promoting interactive and musical Information and Communications Technology (ICT) for families with children with severe disabilities. The project explores a new treatment paradigm based on collaborative, tangible, interactive net-based musical “smart things” with multimedia capabilities. The goal in RHYME is twofold: (1) to reduce isolation and passivity, and (2) to promote health and well-being. Co-creation is suggested as a possible path to achieving these goals, by evoking feelings, for example, or accommodating the needs to act and to create social relations; co-creation also motivates users to communicate and collaborate within (new) social relations. This article engages co-creation by incorporating aspects connected to interaction design and the field of music and health. Empirical observations will be referred to. The research question is as follows: What might co-creation imply for families of children with disabilities when musical and interactive tangibles are used as health-promoting implements? PMID:23930992

Electrical and chemical interactions at Mars Workshop, part 1

NASA Technical Reports Server (NTRS)

1992-01-01

The Electrical and Chemical Interactions at Mars Workshop, hosted by NASA Lewis Research Center on November 19 and 20, 1991, was held with the following objectives in mind: (1) to identify issues related to electrical and chemical interactions between systems and their local environments on Mars, and (2) to recommend means of addressing those issues, including the dispatch of robotic spacecraft to Mars to acquire necessary information. The workshop began with presentations about Mars' surface and orbital environments, Space Exploration Initiative (SEI) systems, environmental interactions, modeling and analysis, and plans for exploration. Participants were then divided into two working groups: one to examine the surface of Mars; and the other, the orbit of Mars. The working groups were to identify issues relating to environmental interactions; to state for each issue what is known and what new knowledge is needed; and to recommend ways to fulfill the need. Issues were prioritized within each working group using the relative severity of effects as a criterion. Described here are the two working groups' contributions. A bibliography of materials used during the workshop and suggested reference materials is included.

DIMA 3.0: Domain Interaction Map.

PubMed

Luo, Qibin; Pagel, Philipp; Vilne, Baiba; Frishman, Dmitrij

2011-01-01

Domain Interaction MAp (DIMA, available at http://webclu.bio.wzw.tum.de/dima) is a database of predicted and known interactions between protein domains. It integrates 5807 structurally known interactions imported from the iPfam and 3did databases and 46,900 domain interactions predicted by four computational methods: domain phylogenetic profiling, domain pair exclusion algorithm correlated mutations and domain interaction prediction in a discriminative way. Additionally predictions are filtered to exclude those domain pairs that are reported as non-interacting by the Negatome database. The DIMA Web site allows to calculate domain interaction networks either for a domain of interest or for entire organisms, and to explore them interactively using the Flash-based Cytoscape Web software.

The Idea Factory: An Interactive Intergroup Exercise

ERIC Educational Resources Information Center

Rosh, Lisa; Leach, Evan

2011-01-01

This article outlines the Idea Factory exercise, an interactive exercise designed to help participants examine group, individual, and organizational factors that affect intergroup conflict. Specific emphasis is placed on exploring the relationship between intra- and intergroup dynamics and identifying managerial practices that foster effective…

Interactive Videodisc at California State University, Fullerton.

ERIC Educational Resources Information Center

Reisman, S.

In January 1987, California State University, Fullerton (CSUF), began to explore the potential of interactive videodisk (IVD) technology on its campus. The challenge of introducing an individualized instructional technology into a cost conscious and conventional teaching environment was formidable, considering the traditional orientation of…

EPA's EnviroAtlas Educational Curriculum

EPA Science Inventory

U.S. EPA’s EnviroAtlas provides a collection of web-based, interactive tools for exploring ecosystem services: an Interactive Map, which provides access to 300+ maps at multiple extents for the U.S., and an Eco-Health Relationship Browser, which displays the linkages betwee...

ULTRAVIOLET RADIATION AND ARSENIC INTERACTIONS: EFFECTS ON CLADOCERANS

EPA Science Inventory

The effects of arsenic and ultraviolet radiation (UV) on cladocerans have been examined separately, however the interaction of these two stresses has not been explored. Potential synergism between these two stresses is possible as arsenic is known to inhibit repair of UV induced ...

Characterizing Interaction with Visual Mathematical Representations

ERIC Educational Resources Information Center

Sedig, Kamran; Sumner, Mark

2006-01-01

This paper presents a characterization of computer-based interactions by which learners can explore and investigate visual mathematical representations (VMRs). VMRs (e.g., geometric structures, graphs, and diagrams) refer to graphical representations that visually encode properties and relationships of mathematical structures and concepts.…

ShapeShop: Towards Understanding Deep Learning Representations via Interactive Experimentation.

PubMed

Hohman, Fred; Hodas, Nathan; Chau, Duen Horng

2017-05-01

Deep learning is the driving force behind many recent technologies; however, deep neural networks are often viewed as "black-boxes" due to their internal complexity that is hard to understand. Little research focuses on helping people explore and understand the relationship between a user's data and the learned representations in deep learning models. We present our ongoing work, ShapeShop, an interactive system for visualizing and understanding what semantics a neural network model has learned. Built using standard web technologies, ShapeShop allows users to experiment with and compare deep learning models to help explore the robustness of image classifiers.

The Relations Between Classroom Interaction and Teacher Ratings of Pupils: An Exploration of One Means by Which a Teacher May Communicate Her Expectancies. Peabody Papers in Human Development.

ERIC Educational Resources Information Center

Dalton, William B.

A study was conducted to test four hypotheses: (1) There are differences in the total number of interactions that a teacher has with pupils whom she has rated differently. (2) The teacher interacts more directly with those pupils she rates low than with those she rates high. (3) The teacher interacts more indirectly fewer times with those pupils…

Qualitative Treatment-Subgroup Interactions in a Randomized Clinical Trial of Treatments for Adolescents with ADHD: Exploring What Cognitive-Behavioral Treatment Works for Whom

PubMed Central

Geurts, Hilde M.; Prins, Pier J. M.; Van Mechelen, Iven; Van der Oord, Saskia

2016-01-01

Objective This study explored qualitative treatment-subgroup interactions within data of a RCT with two cognitive behavioral treatments (CBT) for adolescents with ADHD: a planning-focused (PML) and a solution-focused CBT (SFT). Qualitative interactions imply that which treatment is best differs across subgroups of patients, and are therefore most relevant for personalized medicine. Methods Adolescents with ADHD (N = 159) received either PML or SFT. Pre-, post- and three-month follow-up data were gathered on parent-rated ADHD symptoms and planning problems. Pretreatment characteristics were explored as potential qualitative moderators of pretest to follow-up treatment effects, using an innovative analyses technique (QUINT; Dusseldorp & Van Mechelen, 2014). In addition, qualitative treatment-subgroup interactions for the therapeutic changes from pre- to posttest and from post- to follow-up test were investigated. Results For the entire time span from pretest to follow-up only a quantitative interaction was found, while from posttest to follow-up qualitative interactions were found: Adolescents with less depressive symptoms but more anxiety symptoms showed more improvement when receiving PML than SFT, while for other adolescents the effects of PML and SFT were comparable. Discussion Whereas subgroups in both treatments followed different trajectories, no subgroup was found for which SFT outperformed PML in terms of the global change in symptoms from pretest to three months after treatment. This implies that, based on this exploratory study, there is no need for personalized treatment allocation with regard to the CBTs under study for adolescents with ADHD. However, for a subgroup with comorbid anxiety symptoms but low depression PML clearly appears the treatment of preference. Trial Registration Nederlands Trial Register NTR2142 PMID:26977602

Exploring the molecular mechanisms of electron shuttling across the microbe/metal space

PubMed Central

Paquete, Catarina M.; Fonseca, Bruno M.; Cruz, Davide R.; Pereira, Tiago M.; Pacheco, Isabel; Soares, Cláudio M.; Louro, Ricardo O.

2014-01-01

Dissimilatory metal reducing organisms play key roles in the biogeochemical cycle of metals as well as in the durability of submerged and buried metallic structures. The molecular mechanisms that support electron transfer across the microbe-metal interface in these organisms remain poorly explored. It is known that outer membrane proteins, in particular multiheme cytochromes, are essential for this type of metabolism, being responsible for direct and indirect, via electron shuttles, interaction with the insoluble electron acceptors. Soluble electron shuttles such as flavins, phenazines, and humic acids are known to enhance extracellular electron transfer. In this work, this phenomenon was explored. All known outer membrane decaheme cytochromes from Shewanella oneidensis MR-1 with known metal terminal reductase activity and a undecaheme cytochrome from Shewanella sp. HRCR-6 were expressed and purified. Their interactions with soluble electron shuttles were studied using stopped-flow kinetics, NMR spectroscopy, and molecular simulations. The results show that despite the structural similarities, expected from the available structural data and sequence homology, the detailed characteristics of their interactions with soluble electron shuttles are different. MtrC and OmcA appear to interact with a variety of different electron shuttles in the close vicinity of some of their hemes, and with affinities that are biologically relevant for the concentrations typical found in the medium for this type of compounds. All data support a view of a distant interaction between the hemes of MtrF and the electron shuttles. For UndA a clear structural characterization was achieved for the interaction with AQDS a humic acid analog. These results provide guidance for future work of the manipulation of these proteins toward modulation of their role in metal attachment and reduction. PMID:25018753

Qualitative Treatment-Subgroup Interactions in a Randomized Clinical Trial of Treatments for Adolescents with ADHD: Exploring What Cognitive-Behavioral Treatment Works for Whom.

PubMed

Boyer, Bianca E; Doove, Lisa L; Geurts, Hilde M; Prins, Pier J M; Van Mechelen, Iven; Van der Oord, Saskia

2016-01-01

This study explored qualitative treatment-subgroup interactions within data of a RCT with two cognitive behavioral treatments (CBT) for adolescents with ADHD: a planning-focused (PML) and a solution-focused CBT (SFT). Qualitative interactions imply that which treatment is best differs across subgroups of patients, and are therefore most relevant for personalized medicine. Adolescents with ADHD (N = 159) received either PML or SFT. Pre-, post- and three-month follow-up data were gathered on parent-rated ADHD symptoms and planning problems. Pretreatment characteristics were explored as potential qualitative moderators of pretest to follow-up treatment effects, using an innovative analyses technique (QUINT; Dusseldorp & Van Mechelen, 2014). In addition, qualitative treatment-subgroup interactions for the therapeutic changes from pre- to posttest and from post- to follow-up test were investigated. For the entire time span from pretest to follow-up only a quantitative interaction was found, while from posttest to follow-up qualitative interactions were found: Adolescents with less depressive symptoms but more anxiety symptoms showed more improvement when receiving PML than SFT, while for other adolescents the effects of PML and SFT were comparable. Whereas subgroups in both treatments followed different trajectories, no subgroup was found for which SFT outperformed PML in terms of the global change in symptoms from pretest to three months after treatment. This implies that, based on this exploratory study, there is no need for personalized treatment allocation with regard to the CBTs under study for adolescents with ADHD. However, for a subgroup with comorbid anxiety symptoms but low depression PML clearly appears the treatment of preference. Nederlands Trial Register NTR2142.

Question, Explanation, Follow-Up: A Mechanism for Learning from Others?

ERIC Educational Resources Information Center

Kurkul, Katelyn E.; Corriveau, Kathleen H.

2018-01-01

This study explored differences in caregiver-child interactions following children's information-seeking questions. Naturalistic speech from thirty-seven 4-year-olds and their caregivers was used to explore children's information-seeking questions, the caregiver's response, and children's subsequent follow-up. Half of the families were…

Curious Play: Children's Exploration of Nature

ERIC Educational Resources Information Center

Gurholt, Kirsti Pedersen; Sanderud, Jostein Rønning

2016-01-01

This article explores the concept of "curious play" as a theoretical framework to understand and communicate children's experiences of free play in nature. The concept emerged interactively from three sources of inspiration: an ethnographically inspired study of children playing in nature; as a critique of the concept of "risky…

Designing Digital Environments for Art Education/Exploration.

ERIC Educational Resources Information Center

Milekic, Slavko

2000-01-01

Examines the role of digital technology in the context of art education and art exploration. Discusses the development of digital environments as the next step in the evolution of traditional computers, whose main characteristic is support for simultaneous multiple-user interactions and for social and collaborative activities. (LRW)

Exploring Collaborative Learning Effect in Blended Learning Environments

ERIC Educational Resources Information Center

Sun, Z.; Liu, R.; Luo, L.; Wu, M.; Shi, C.

2017-01-01

The use of new technology encouraged exploration of the effectiveness and difference of collaborative learning in blended learning environments. This study investigated the social interactive network of students, level of knowledge building and perception level on usefulness in online and mobile collaborative learning environments in higher…

EnviroAtlas: Exploring Ecosystem Services and Biodiversity Data for the Nation.

EPA Science Inventory

EnviroAtlas is an online collection of interactive tools and spatially explicit data allowing users to explore the many benefits people receive from nature. The purpose of EnviroAtlas is to provide better access to consistently derived ecosystems and socio-economic data to facil...

Exploring the linkages among urban form travel behavior and public health with person level data from smart phone applications.

DOT National Transportation Integrated Search

2013-09-01

The interaction between the built environment, travel behavior and public health is now a major concern for both : researchers and urban planners. Currently, there is little empirical research that explores and examines the : relationship between eac...

A Mixed-Methods Exploration of an Environment for Learning Computer Programming

ERIC Educational Resources Information Center

Mather, Richard

2015-01-01

A mixed-methods approach is evaluated for exploring collaborative behaviour, acceptance and progress surrounding an interactive technology for learning computer programming. A review of literature reveals a compelling case for using mixed-methods approaches when evaluating technology-enhanced-learning environments. Here, ethnographic approaches…

Structure of local interactions in complex financial dynamics

PubMed Central

Jiang, X. F.; Chen, T. T.; Zheng, B.

2014-01-01

With the network methods and random matrix theory, we investigate the interaction structure of communities in financial markets. In particular, based on the random matrix decomposition, we clarify that the local interactions between the business sectors (subsectors) are mainly contained in the sector mode. In the sector mode, the average correlation inside the sectors is positive, while that between the sectors is negative. Further, we explore the time evolution of the interaction structure of the business sectors, and observe that the local interaction structure changes dramatically during a financial bubble or crisis. PMID:24936906

Two interacting Hofstadter butterflies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barelli, A.; Bellissard, J.; Jacquod, P.

1997-04-01

The problem of two interacting particles in a quasiperiodic potential is addressed. Using analytical and numerical methods, we explore the spectral properties and eigenstates structure from the weak to the strong interaction case. More precisely, a semiclassical approach based on noncommutative geometry techniques is used to understand the intricate structure of such a spectrum. An interaction induced localization effect is furthermore emphasized. We discuss the application of our results on a two-dimensional model of two particles in a uniform magnetic field with on-site interaction. {copyright} {ital 1997} {ital The American Physical Society}

MyMoon: Engaging the “Missing Link” in Lunar Science Exploration through New Media

NASA Astrophysics Data System (ADS)

Shaner, A.; Shupla, C.; Shipp, S. S.; Eriksson, A.

2009-12-01

NASA’s new scientific exploration of the Moon, coupled with the public’s interest in the Moon and innovative social networking approaches, is being leveraged to engage a fresh adult audience in lunar science and exploration. In July 2009 the Lunar and Planetary Institute (LPI) launched a lunar education new media portal, MyMoon. LPI is collaborating with lunar scientists, educators, artists - and the public - to populate the site with science content, diverse media exhibits, events, and opportunities for involvement. Through MyMoon, the general public interacts with lunar content that informs them about lunar science research and missions, and engages them in future plans for lunar exploration and eventual habitation. MyMoon’s objectives are to: 1) develop a dynamic, new media learning portal that will enable the general public, with a focus on adults ages 18-35; 2) host a growing, active audience that becomes further involved in NASA’s lunar exploration by sharing their ideas about lunar topics, creating their own materials, and participating in events and experiences; 3) build a community of enthusiasts through social networking media; 4) create a model for online engagement of audiences 18 to 35, and provide detailed evaluation data on best practices and strategies for success. Immersive new media technologies are changing the way that people interact, work, learn, and teach. These provide potentially high-impact opportunities for reaching an audience of young adults, age 18 to 35, that largely is not accessed by, or accessing, NASA (Dittmar, 2004). MyMoon strives to engage - and involve - this audience to build a community of enthusiasts for lunar scientific exploration through social networks and current and emerging new media platforms, including posting videos on YouTube, photo contests on Flickr, and sharing events and challenges on Facebook and Twitter. MyMoon features interactive exhibits that are audience driven and added on a quarterly basis. Contests and polls encourage audience involvement. Semi-monthly webcasts allow audience members to interact directly with scientists, authors, and artists. A guest blog encourages audience responses to current lunar events and provocative viewpoints. Evaluation is an integral component to the MyMoon project. Evaluation data are obtained in short bursts through visitor feedback, prompted by a virtual squirrel who dares visitors to share their impressions, ideas, and interests in lunar science and exploration. Based on evaluation data, the current challenge that faces MyMoon is marketing further to the target audience; numerous approaches are being tested and evaluated. Dittmar, M. 2004, “The Market Study for Space Exploration,” (Houston, TX, Dittmar Associates, Inc.)

Give Me a Hand: Adult Involvement During Object Exploration Affects Object Individuation in Infancy

PubMed Central

Johnson, Kristin M.; Woods, Rebecca J.

2015-01-01

The development of object individuation, a fundamental ability that supports identification and discrimination of objects across discrete encounters, has been examined extensively by researchers. There are significant advancements in infants’ ability to individuate objects during the first year-and-a-half. Experimental work has established a timeline of object individuation abilities and revealed some mechanisms underlying this ability, however, the influence of adult assistance during object exploration has not yet been explored. The current study investigates the effect of adult involvement during object exploration on infants’ object individuation abilities. In Experiment 1a and 1b, we examined 9.5-month-old infants’ colour-based object individuation following adult-assisted multisensory object exploration. Two components of adult interaction were of particular interest: facilitation of object manipulation (grasping, rotating, and attention-getting behaviours) and social engagement (smiling, pointing, attention-getting verbalizations, and object-directed gaze). Experiment 2a and 2b assessed these components with 4.5-month-olds to examine their impact across development. The results showed that after adult-guided object exploration, both 9.5- and 4.5-month-old infants successfully individuated previously undifferentiated objects. Results of Experiments 1b and 2b provide implications for the mechanisms underlying the scaffolding influence of adult interaction during infant behaviours. PMID:28082834

Interactive Tabletops in Education

ERIC Educational Resources Information Center

Dillenbourg, Pierre; Evans, Michael

2011-01-01

Interactive tabletops are gaining increased attention from CSCL researchers. This paper analyses the relation between this technology and teaching and learning processes. At a global level, one could argue that tabletops convey a socio-constructivist flavor: they support small teams that solve problems by exploring multiple solutions. The…

Powdered hide model for vegetable tanning II. hydrolyzable tannin

USDA-ARS?s Scientific Manuscript database

Vegetable tannages employ both condensed and hydrolyzable tannins. As part of our exploration of tanning mechanisms, we reported last year on interactions of the condensed tannin, quebracho, with powdered hide. In this study, the interactions of chestnut extract, a hydrolyzable tannin, with powdere...

Lonely Individuals Do Not Show Interpersonal Self-Positivity Bias: Evidence From N400

PubMed Central

Zhu, Min; Zhu, Changzheng; Gao, Xiangping; Luo, Junlong

2018-01-01

Self-positivity bias is one of the well-studied psychological phenomena, however, little is known about the bias in the specific dimension on social interaction, which we called herein interpersonal self-positivity bias—people tend to evaluate themselves more positively on social interactions, prefer to be included rather than to be excluded by others. In the present study, we used a modified self-reference task associated with N400 to verify such bias and explore whether impoverished social interaction (loneliness) could modulate it. Findings showed that exclusion verbs elicited larger N400 amplitudes than inclusion verbs, suggesting that most people have interpersonal self-positivity bias. However, loneliness was significantly correlated with N400 effect, showing those with high scores of loneliness had smaller differences in the N400 than those with lower scores. These findings indicated impoverished social interaction weakens interpersonal self-positivity bias; however, the underlying mechanisms need to be explored in future research. PMID:29681875

Exploring the use of tablet PCs in veterinary medical education: opportunity or obstacle?

PubMed

Wang, Hong; Rush, Bonnie R; Wilkerson, Melinda; van der Merwe, Deon

2014-01-01

A tablet PC is a laptop computer with a touch screen and a digital pen or stylus that can be used for handwritten notes and drawings. The use of tablet PCs has been investigated in many disciplines such as engineering, mathematics, science, and education. The purpose of this article is to explore student and faculty attitudes toward and experiences with tablet PCs 6 years after the implementation of a tablet PC program in the College of Veterinary Medicine (CVM) at Kansas State University (K-State). This study reports that the use of tablet PCs has enhanced students' learning experiences through learner-interface interaction, learner-content interaction, learner-instructor interaction, and learner-learner interaction. This study also identifies digital distraction as the major negative experience with tablet PCs during class time. The tablet PC program provides CVM faculty the potential to pursue technology integration strategies that support expected learning outcomes and provides students the potential to develop self-monitoring and self-discipline skills that support learning with digital technologies.

A qualitative geographical information systems approach to explore how older people over 70 years interact with and define their neighbourhood environment

PubMed Central

Milton, Sarah; Pliakas, Triantafyllos; Hawkesworth, Sophie; Nanchahal, Kiran; Grundy, Chris; Amuzu, Antoinette; Casas, Juan-Pablo; Lock, Karen

2015-01-01

A growing body of literature explores the relationship between the built environment and health, and the methodological challenges of understanding these complex interactions across the lifecourse. The impact of the neighbourhood environment on health and behaviour amongst older adults has received less attention, despite this age group being potentially more vulnerable to barriers in their surrounding social and physical environment. A qualitative geographical information systems (QGIS) approach was taken to facilitate the understanding of how older people over 70 in 5 UK towns interact with their local neighbourhood. The concept of neighbourhood changed seasonally and over the lifecourse, and was associated with social factors such as friends, family, or community activities, rather than places. Spaces stretched further than the local, which is problematic for older people who rely on variable public transport provision. QGIS techniques prompted rich discussions on interactions with and the meanings of ‘place’ in older people. PMID:26513597

Predators determine how weather affects the spatial niche of lizard prey: exploring niche dynamics at a fine scale.

PubMed

Lopez-Darias, Marta; Schoener, Thomas W; Spiller, David A; Losos, Jonathan B

2012-12-01

Although abiotic and biotic factors can interact to shape the spatial niche of a species, studies that explore the interactive effects of both at a local scale are rare. We demonstrate that one of the main axes (perch height) characterizing the spatial niche of a common lizard, Anolis sagrei, varies according to the interactive effects of weather and the activity of a larger predatory lizard, Leiocephalus carinatus. Results were completely consistent: no matter how favorable the weather conditions for using the ground (mainly characterized by temperature, humidity, wind speed, rain), A. sagrei did not do so if the predator was present. Hence, great behavioral plasticity enabled A. sagrei to adjust its use of space very quickly. To the best of our knowledge, these results constitute the first field demonstration for anoles (and possibly for other animals as well) of how time-varying environmental conditions and predator presence interact to produce short-term changes in utilization along a major niche axis.

Constraint programming based biomarker optimization.

PubMed

Zhou, Manli; Luo, Youxi; Sun, Guoquan; Mai, Guoqin; Zhou, Fengfeng

2015-01-01

Efficient and intuitive characterization of biological big data is becoming a major challenge for modern bio-OMIC based scientists. Interactive visualization and exploration of big data is proven to be one of the successful solutions. Most of the existing feature selection algorithms do not allow the interactive inputs from users in the optimizing process of feature selection. This study investigates this question as fixing a few user-input features in the finally selected feature subset and formulates these user-input features as constraints for a programming model. The proposed algorithm, fsCoP (feature selection based on constrained programming), performs well similar to or much better than the existing feature selection algorithms, even with the constraints from both literature and the existing algorithms. An fsCoP biomarker may be intriguing for further wet lab validation, since it satisfies both the classification optimization function and the biomedical knowledge. fsCoP may also be used for the interactive exploration of bio-OMIC big data by interactively adding user-defined constraints for modeling.

Bringing hands-on exploration of air quality technology to the ...

EPA Pesticide Factsheets

This is an educational presentation to the OAQPS Teachers Workshop on the PM sensor kit and other related air technology educational activities. This workshop for teachers and other educators includes topics, such as: how EPA manages air quality, the environmental health effects and risks of air pollution, climate change, and sustainability solutions and more. Attendees will also build a DYI Sensor kit and explore energy choices and the environment when they play the interactive board game developed by EPA scientists called Generate! This workshop for teachers and other educators includes topics, such as: how EPA manages air quality, the environmental health effects and risks of air pollution, climate change and sustainability and more. Attendees will also build a DYI Sensor kit and explore energy choices and the environment when they play the interactive board game developed by EPA scientists called Generate!

Social Orders and Interactions among Children in Age-Mixed Classes in Primary Schools--New Perspectives from a Synthesis of Ethnographic Data

ERIC Educational Resources Information Center

Huf, Christina; Raggl, Andrea

2015-01-01

The article synthesises data from two ethnographic projects, which both explore interactions of children in age-mixed groups in primary schools. It illuminates critical perspectives on social orders and children's interactions in age-mixed classes by showing how pupils in age-mixed groups become involved in power relations and how the teacher's…

Next-generation analysis of cataracts: determining knowledge driven gene-gene interactions using Biofilter, and gene-environment interactions using the PhenX Toolkit.

PubMed

Pendergrass, Sarah A; Verma, Shefali S; Holzinger, Emily R; Moore, Carrie B; Wallace, John; Dudek, Scott M; Huggins, Wayne; Kitchner, Terrie; Waudby, Carol; Berg, Richard; McCarty, Catherine A; Ritchie, Marylyn D

2013-01-01

Investigating the association between biobank derived genomic data and the information of linked electronic health records (EHRs) is an emerging area of research for dissecting the architecture of complex human traits, where cases and controls for study are defined through the use of electronic phenotyping algorithms deployed in large EHR systems. For our study, 2580 cataract cases and 1367 controls were identified within the Marshfield Personalized Medicine Research Project (PMRP) Biobank and linked EHR, which is a member of the NHGRI-funded electronic Medical Records and Genomics (eMERGE) Network. Our goal was to explore potential gene-gene and gene-environment interactions within these data for 529,431 single nucleotide polymorphisms (SNPs) with minor allele frequency > 1%, in order to explore higher level associations with cataract risk beyond investigations of single SNP-phenotype associations. To build our SNP-SNP interaction models we utilized a prior-knowledge driven filtering method called Biofilter to minimize the multiple testing burden of exploring the vast array of interaction models possible from our extensive number of SNPs. Using the Biofilter, we developed 57,376 prior-knowledge directed SNP-SNP models to test for association with cataract status. We selected models that required 6 sources of external domain knowledge. We identified 5 statistically significant models with an interaction term with p-value < 0.05, as well as an overall model with p-value < 0.05 associated with cataract status. We also conducted gene-environment interaction analyses for all GWAS SNPs and a set of environmental factors from the PhenX Toolkit: smoking, UV exposure, and alcohol use; these environmental factors have been previously associated with the formation of cataracts. We found a total of 288 models that exhibit an interaction term with a p-value ≤ 1×10(-4) associated with cataract status. Our results show these approaches enable advanced searches for epistasis and gene-environment interactions beyond GWAS, and that the EHR based approach provides an additional source of data for seeking these advanced explanatory models of the etiology of complex disease/outcome such as cataracts.

Differences and similarities between father-infant interaction and mother-infant interaction.

PubMed

Yago, Satoshi; Hirose, Taiko; Okamitsu, Motoko; Okabayashi, Yukiko; Hiroi, Kayoko; Nakagawa, Nozomi; Omori, Takahide

2014-03-19

The aim of this study was to compare father-infant interaction with mother-infant interaction, and explore differences and similarities between parents. Related factors for quality of father-infant interaction were also examined. Sixteen pairs of parents with infants aged 0 to 36 months were observed for play interaction between parents and their children. Results suggested no significant differences between parents, but children's interactions were significantly more contingent with fathers than mothers (p =.045). Significant correlations between parents were found in socialemotional growth fostering encouragement for children during interaction (ρ =.73, p =.001). Paternal depressive symptoms were significantly correlated to paternal sensitivity to child's cues (ρ =-.59, p =.017).

Interaction of grapefruit juice and calcium channel blockers.

PubMed

Sica, Domenic A

2006-07-01

Drug-drug interactions are commonly recognized occurrences in the hypertensive population. Drug-nutrient interactions, however, are less well appreciated. The grapefruit juice-calcium channel blocker interaction is one that has been known since 1989. The basis for this interaction has been diligently explored and appears to relate to both flavanoid and nonflavanoid components of grapefruit juice interfering with enterocyte CYP3A4 activity. In the process, presystemic clearance of susceptible drugs decreases and bioavailability increases. A number of calcium channel blockers are prone to this interaction, with the most prominent interaction occurring with felodipine. The calcium channel blocker and grapefruit juice interaction should be incorporated into the knowledge base of rational therapeutics for the prescribing physician.

A Comprehensive Tool for Exploring the Availability, Scalability and Growth Potential of Conventional and Renewable Energy Sources and Technologies

NASA Astrophysics Data System (ADS)

Jack-Scott, E.; Arnott, J. C.; Katzenberger, J.; Davis, S. J.; Delman, E.

2015-12-01

It has been a generational challenge to simultaneously meet the world's energy requirements, while remaining within the bounds of acceptable cost and environmental impact. To this end, substantial research has explored various energy futures on a global scale, leaving decision-makers and the public overwhelmed by information on energy options. In response, this interactive energy table was developed as a comprehensive resource through which users can explore the availability, scalability, and growth potentials of all energy technologies currently in use or development. Extensive research from peer-reviewed papers and reports was compiled and summarized, detailing technology costs, technical considerations, imminent breakthroughs, and obstacles to integration, as well as political, social, and environmental considerations. Energy technologies fall within categories of coal, oil, natural gas, nuclear, solar, wind, hydropower, ocean, geothermal and biomass. In addition to 360 expandable cells of cited data, the interactive table also features educational windows with background information on each energy technology. The table seeks not to advocate for specific energy futures, but to succinctly and accurately centralize peer-reviewed research and information in an interactive, accessible resource. With this tool, decision-makers, researchers and the public alike can explore various combinations of energy technologies and their quantitative and qualitative attributes that can satisfy the world's total primary energy supply (TPES) while making progress towards a near zero carbon future.

Adenosine A2A receptor deletion affects social behaviors and anxiety in mice: Involvement of anterior cingulate cortex and amygdala.

PubMed

López-Cruz, Laura; Carbó-Gas, Maria; Pardo, Marta; Bayarri, Pilar; Valverde, Olga; Ledent, Catherine; Salamone, John D; Correa, Mercè

2017-03-15

Blockade of adenosine A 2A receptors can potentiate motivation to work for natural reinforcers such as food. Conspecific interaction is a potent natural reinforcer in social animals that can be manifested as preference for social exploration versus other sources of novel stimulation. Deficiencies in this type of motivated behavior (social withdrawal) have been seen in several pathologies such as autism and depression. However, the role of A 2A receptors in motivation for social interaction has not been widely explored. Social interaction paradigms evaluate the natural preference of animals for exploring other conspecifics, and the ability to differentiate between familiar versus novel ones. Anxiety is one of the factors that can induce avoidance of social interaction. In the present study, adenosine A 2A knockout (A 2A KO) and wild-type (WT) mice were assessed for social and anxiety-related behaviors. c-Fos immunoreactivity was evaluated as a measure of neuronal activation in brain areas involved in different aspects of motivation and emotional processes. Although A 2A KO mice showed an anxious profile, they displayed higher levels of sociability and were less sensitive to social novelty. WT mice displayed a typical pattern of social recognition 24h later, but not A 2A KO mice, which explored equally both conspecifics. There were no differences between strains in aggressiveness, perseverance or social odor preferences. c-Fos immunoreactivity in A 2A KO mice was higher in anterior cingulate and amygdala compared to WT mice. Thus, A 2A receptors appear to be potential targets for the improvement of pathologies related to social function. Copyright © 2016 Elsevier B.V. All rights reserved.

An interactive, multi-touch videowall for scientific data exploration

NASA Astrophysics Data System (ADS)

Blower, Jon; Griffiths, Guy; van Meersbergen, Maarten; Lusher, Scott; Styles, Jon

2014-05-01

The use of videowalls for scientific data exploration is rising as hardware becomes cheaper and the availability of software and multimedia content grows. Most videowalls are used primarily for outreach and communication purposes, but there is increasing interest in using large display screens to support exploratory visualization as an integral part of scientific research. In this PICO presentation we will present a brief overview of a new videowall system at the University of Reading, which is designed specifically to support interactive, exploratory visualization activities in climate science and Earth Observation. The videowall consists of eight 42-inch full-HD screens (in 4x2 formation), giving a total resolution of about 16 megapixels. The display is managed by a videowall controller, which can direct video to the screen from up to four external laptops, a purpose-built graphics workstation, or any combination thereof. A multi-touch overlay provides the capability for the user to interact directly with the data. There are many ways to use the videowall, and a key technical challenge is to make the most of the touch capabilities - touch has the potential to greatly reduce the learning curve in interactive data exploration, but most software is not yet designed for this purpose. In the PICO we will present an overview of some ways in which the wall can be employed in science, seeking feedback and discussion from the community. The system was inspired by an existing and highly-successful system (known as the "Collaboratorium") at the Netherlands e-Science Center (NLeSC). We will demonstrate how we have adapted NLeSC's visualization software to our system for touch-enabled multi-screen climate data exploration.

Life in the dark: Roots and how they regulate plant-soil interactions

NASA Astrophysics Data System (ADS)

Wu, Y.; Chou, C.; Peruzzo, L.; Riley, W. J.; Hao, Z.; Petrov, P.; Newman, G. A.; Versteeg, R.; Blancaflor, E.; Ma, X.; Dafflon, B.; Brodie, E.; Hubbard, S. S.

2017-12-01

Roots play a key role in regulating interactions between soil and plants, an important biosphere process critical for soil development and health, global food security, carbon sequestration, and the cycling of elements (water, carbon, nutrients, and environmental contaminants). However, their underground location has hindered studies of plant roots and the role they play in regulating plant-soil interactions. Technological limitations for root phenotyping and the lack of an integrated approach capable of linking root development, its environmental adaptation/modification with subsequent impact on plant health and productivity are major challenges faced by scientists as they seek to understand the plant's hidden half. To overcome these challenges, we combine novel experimental methods with numerical simulations, and conduct controlled studies to explore the dynamic growth of crop roots. We ask how roots adapt to and change the soil environment and their subsequent impacts on plant health and productivity. Specifically, our efforts are focused on (1) developing novel geophysical approaches for non-invasive plant root and rhizosphere characterization; (2) correlating root developments with key canopy traits indicative of plant health and productivity; (3) developing numerical algorithms for novel geophysical root signal processing; (4) establishing plant growth models to explore root-soil interactions and above and below ground traits co-variabilities; and (5) exploring how root development modifies rhizosphere physical, hydrological, and geochemical environments for adaptation and survival. Our preliminary results highlight the potential of using electro-geophysical methods to quantifying key rhizosphere traits, the capability of the ecosys model for mechanistic plant growth simulation and traits correlation exploration, and the combination of multi-physics and numerical approach for a systematic understanding of root growth dynamics, impacts on soil physicochemical environments, and plant health and productivity.

Teachers' Beliefs and Practices: A Dynamic and Complex Relationship

ERIC Educational Resources Information Center

Zheng, Hongying

2013-01-01

Research on teachers' beliefs has provided useful insights into understanding processes of teaching. However, no research has explored teachers' beliefs as a system nor have researchers investigated the substance of interactions between teachers' beliefs, practices and context. Therefore, the author adopts complexity theory to explore the features…

HADES overview

NASA Astrophysics Data System (ADS)

Galatyuk, Tetyana; Hades Collaboration

2014-11-01

The HADES experiment explores strongly interacting baryon-rich matter at moderate temperatures using rare and penetrating probes. It operates in the beam-energy range of 1- 2 A GeV where comparatively long-lived states of compressed matter are created. This contribution discusses the role of dilepton and strangeness spectroscopy in the exploration of such matter.

Writing with Parents in Response to Picture Book Read Alouds

ERIC Educational Resources Information Center

DeFauw, Danielle L.

2017-01-01

High-quality writing instruction needs to permeate elementary students' in- and outside-of-school experiences. The aim of this research was to explore how teaching writing to parents may support home-school literacy connections. This qualitative case study explored parents' experiences in interactive writing sessions. The descriptive coding and…

Exploration of Peer-Facilitator Dynamics in Two Contrasting Groups

ERIC Educational Resources Information Center

Chen, Fei-ching; Jiang, Huo-ming

2004-01-01

Utilizing an integration of social-cognitivist and socio-cultural approaches, this study--comparing the interactive processes among peers and their mentor in two contrasting groups--was designed to explore the reasons why two learning groups, engaged in an inquiry-based learning project with comparatively sustained discussion, produced vastly…

Vignettes of Interviews to Enhance an Ethnographic Account

ERIC Educational Resources Information Center

Jacobsen, Alice Juel

2014-01-01

This article explores challenges of applying an ethnographic approach, combining participant observation and interviews, to a study of organizational change. The exploration is connected to reform changes, as they are constructed in the interaction between managers and teachers, in a Danish Upper Secondary High School. The data material is…

Environmental Identity Development through Social Interactions, Action, and Recognition

ERIC Educational Resources Information Center

Stapleton, Sarah Riggs

2015-01-01

This article uses sociocultural identity theory to explore how practice, action, and recognition can facilitate environmental identity development. Recognition, a construct not previously explored in environmental identity literature, is particularly examined. The study is based on a group of diverse teens who traveled to South Asia to participate…

A Case Study of International Students' Social Adjustment, Friendship Development, and Physical Activity

ERIC Educational Resources Information Center

Li, Shuang; Zizzi, Sam

2018-01-01

Previous literature has focused on international student's social transition and monocultural and bicultural ties. Little research has explored international students' multicultural friendship development and the role that physical activity plays in their social interaction. The current case study explored a group of international students'…

Small Talk: Children's Everyday "Molecule" Ideas

ERIC Educational Resources Information Center

Jakab, Cheryl

2013-01-01

This paper reports on 6-11-year-old children's "sayings and doings" (Harré 2002) as they explore molecule artefacts in dialectical-interactive teaching interviews (Fleer, "Cultural Studies of Science Education" 3:781-786, 2008; Hedegaard et al. 2008). This sociocultural study was designed to explore children's…

Can Generating Representations Enhance Learning with Dynamic Visualizations?

ERIC Educational Resources Information Center

Zhang, Zhihui Helen; Linn, Marcia C.

2011-01-01

This study explores the impact of asking middle school students to generate drawings of their ideas about chemical reactions on integrated understanding. Students explored atomic interactions during hydrogen combustion using a dynamic visualization. The generation group drew their ideas about how the reaction takes place at the molecular level.…

Using Playful Practice to Communicate with Special Children. David Fulton/Nasen

ERIC Educational Resources Information Center

Corke, Margaret

2011-01-01

Playfulness is important; it creates an alternative space where emotional, cognitive and social dimensions can be explored and tested. This highly practical book explores the endless possibilities of using playful, creative and interactive activities to meaningfully engage with children with multiple learning difficulties or autistic spectrum…

Exploring Environmental Identity and Behavioral Change in an Environmental Science Course

ERIC Educational Resources Information Center

Blatt, Erica N.

2013-01-01

This ethnographic study at a public high school in the Northeastern United States investigates the process of change in students' environmental identity and proenvironmental behaviors during an Environmental Science course. The study explores how sociocultural factors, such as students' background, social interactions, and classroom structures,…

Self-Presentation and Gender on MySpace

ERIC Educational Resources Information Center

Manago, Adriana M.; Graham, Michael B.; Greenfield, Patricia M.; Salimkhan, Goldie

2008-01-01

Within the cultural context of MySpace, this study explores the ways emerging adults experience social networking. Through focus group methodology, the role of virtual peer interaction in the development of personal, social, and gender identities was investigated. Findings suggest that college students utilize MySpace for identity exploration,…

Therapeutic Theory and Social Context: A Social Constructionist Perspective.

ERIC Educational Resources Information Center

Lynch, Gordon

1997-01-01

Explores the foundation of therapeutic theory from the perspective of social constructionism. Proposes a theoretical description of the interaction between an individual and the social context in the formation of therapeutic theory. Then explores this description in relation to the early life and subsequent therapeutic theory of Carl Rogers. (RJM)

Experience[superscript]2

ERIC Educational Resources Information Center

Barker, Kim

2011-01-01

Researching whimsical and spirited artists can inspire new ideas and methods of communicating how art remains a valuable part of people's lives both in and out of the classroom. This instructional resource explores one such contemporary artist who, driven by a curiosity in human interaction, continues to explore the world in fanciful and…

Exploring the Development of Fifth Graders' Practical Epistemologies and Explanation Skills in Inquiry-Based Learning Classrooms

ERIC Educational Resources Information Center

Wu, Hsin-Kai; Wu, Chia-Lien

2011-01-01

The purposes of this study are to explore fifth graders' epistemological views regarding their own experiences of constructing scientific knowledge through inquiry activities (i.e., practical epistemologies) and to investigate possible interactions between students' practical epistemologies and their inquiry skills to construct scientific…

The Relationship between Philosophy and Evidence in Education

ERIC Educational Resources Information Center

Schouten, Gina; Brighouse, Harry

2015-01-01

This article explores the ways that philosophy and evidence interact in the exploration of normative questions in philosophy of education. First, the authors provide a description of reflective equilibrium, a central method in normative philosophizing. They proceed to describe three tasks of normative philosophy, each of which requires engagement…

Social Motor Synchronization: Insights for Understanding Social Behavior in Autism

ERIC Educational Resources Information Center

Fitzpatrick, Paula; Romero, Veronica; Amaral, Joseph L.; Duncan, Amie; Barnard, Holly; Richardson, Michael J.; Schmidt, R. C.

2017-01-01

Impairments in social interaction and communication are critical features of ASD but the underlying processes are poorly understood. An under-explored area is the social motor synchronization that happens when we coordinate our bodies with others. Here, we explored the relationships between dynamical measures of social motor synchronization and…

Influence of depth of interaction upon the performance of scintillator detectors.

PubMed

Brown, Mark S; Gundacker, Stefan; Taylor, Alaric; Tummeltshammer, Clemens; Auffray, Etiennette; Lecoq, Paul; Papakonstantinou, Ioannis

2014-01-01

The uncertainty in time of particle detection within a scintillator detector, characterised by the coincidence time resolution (CTR), is explored with respect to the interaction position within the scintillator crystal itself. Electronic collimation between two scintillator detectors is utilised to determine the CTR with depth of interaction (DOI) for different materials, geometries and wrappings. Significantly, no relationship between the CTR and DOI is observed within experimental error. Confinement of the interaction position is seen to degrade the CTR in long scintillator crystals by 10%.

Methods to Assess the Direct Interaction of C. jejuni with Mucins.

PubMed

Clyne, Marguerite; Duggan, Gina; Naughton, Julie; Bourke, Billy

2017-01-01

Studies of the interaction of bacteria with mucus-secreting cells can be complemented at a more mechanistic level by exploring the interaction of bacteria with purified mucins. Here we describe a far Western blotting approach to show how C. jejuni proteins separated by SDS PAGE and transferred to a membrane or slot blotted directly onto a membrane can be probed using biotinylated mucin. In addition we describe the use of novel mucin microarrays to assess bacterial interactions with mucins in a high-throughput manner.

The ADAMS interactive interpreter

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rietscha, E.R.

1990-12-17

The ADAMS (Advanced DAta Management System) project is exploring next generation database technology. Database management does not follow the usual programming paradigm. Instead, the database dictionary provides an additional name space environment that should be interactively created and tested before writing application code. This document describes the implementation and operation of the ADAMS Interpreter, an interactive interface to the ADAMS data dictionary and runtime system. The Interpreter executes individual statements of the ADAMS Interface Language, providing a fast, interactive mechanism to define and access persistent databases. 5 refs.

Exploring Multitarget Interactions to Reduce Opiate Withdrawal Syndrome and Psychiatric Comorbidity

PubMed Central

2013-01-01

Opioid addiction is often characterized as a chronic relapsing condition due to the severe somatic and behavioral signs, associated with depressive disorders, triggered by opiate withdrawal. Since prolonged abstinence remains a major challenge, our interest has been addressed to such objective. Exploring multitarget interactions, the present investigation suggests that 3 or its (S)-enantiomer and 4, endowed with effective α2C-AR agonism/α2A-AR antagonism/5-HT1A-R agonism, or 7 and 9–11 producing efficacious α2C-AR agonism/α2A-AR antagonism/I2–IBS interaction might represent novel multifunctional tools potentially useful for reducing withdrawal syndrome and associated depression. Such agents, lacking in sedative side effects due to their α2A-AR antagonism, might afford an improvement over current therapies with clonidine-like drugs. PMID:24900763

Anthropological Perspectives on Participation in CBPR: Insights From the Water Project, Maras, Peru.

PubMed

Cartwright, Elizabeth; Schow, Diana

2016-01-01

In this article, we anthropologically explore one part of the process of Community-Based Participatory Research (CBPR): participation. Participation in CBPR is usually conceptualized as whether, and the degree to which, community members are involved in the research process. Our focus regarding participation is less on quantity and more on quality of the interaction between community members and researchers; within this context, we elaborate the concept of "bridging" as it is understood in CBPR. Using data from our ongoing "Water Project" in the Peruvian Andes, we explore how interaction, as a participative act of the research interview, creates the space for participating and imagining. Out of this interaction come data that are elaborated, contextualized, and, ultimately, from a CBPR perspective, made useful for meaningful engagement and community action. © The Author(s) 2015.

Contextualizing Community in Teacher Bible Talk

ERIC Educational Resources Information Center

Avni, Sharon

2013-01-01

This paper explores the interactions surrounding Bible teaching as a means of understanding how Jewish youth are discursively implicated within ideologies of community. Drawing on theoretical frameworks from linguistic anthropology and interactional sociolinguistics, I present a micro-analysis of a classroom lesson on the book of Leviticus to…

An Exploration of Interactions between Virtual Mentors and Preservice Teachers

ERIC Educational Resources Information Center

Reese, Jill

2017-01-01

This study describes interactions between preservice music teachers and experienced teachers during virtual mentoring sessions embedded in field experiences for an elementary general music methods course. Participants were preservice music teachers (mentees) and experienced teachers (mentors). Videos of six mentoring sessions were transcribed,…

Discursive Tactical Negotiations within and across Literacy Coaching Interactions

ERIC Educational Resources Information Center

Hunt, Carolyn S.

2013-01-01

In this dissertation, the researcher employed de Certeau's theoretical insights into cultural production in everyday life to examine how literacy coaches and teachers discursively negotiated issues of identity, power, and positioning during coaching interactions. The study also explored how literacy coaches and teachers enacted emotions within…

THE INTERACTION OF AN ANTICHOLINESTERASE INSECTICIDE, DIAZINON, WITH A PYRETHROID INSECTICIDE, DELTAMETHRIN.

EPA Science Inventory

This present study explores the interaction of the toxicity induced by an organophosphorus insecticide, diazinon (diethyl 2-isopropyl-6methyl-4-pyrimidal phosphorothionate), with a pyrethroid insecticide, deltamethrin ((S)-a-cyano-3-phenoxybenzyl (1R,3R)-3-(2,2-dibromovinyl)-2,...

Sectoral Patterns of Interactive Learning: An Empirical Exploration of a Case in a Dutch Region.

ERIC Educational Resources Information Center

Meeus, Marius T. H.; Oerlemans, Leon A. G.; Hage, Jerald

2001-01-01

Pursues the development of a theoretical framework that explains interactive learning between innovator firms and external actors in both the knowledge infrastructure and the production chain. Analyzes models in four sectors with distinct technological dynamics as distinguished by Pavitt. (DDR)

Planned e-Learning Adoption and Occupational Socialisation in Brazilian Higher Education

ERIC Educational Resources Information Center

Renda dos Santos, Luiz Miguel; Okazaki, Shintaro

2016-01-01

This study applies the decomposed theory of planned behaviour to explore university faculty members' e-learning adoption in Brazil. Attitude (perceived usefulness, ease of use, compatibility, and relative advantage), subjective norms (external influence and student-instructor interaction), and behavioural control (level of interactivity and…

Teaching science with technology: Using EPA’s EnviroAtlas in the classroom

EPA Science Inventory

Background/Question/Methods U.S. EPA’s EnviroAtlas provides a collection of web-based, interactive tools and resources for exploring ecosystem goods and services. EnviroAtlas contains two primary tools: An Interactive Map, which provides access to 300+ maps at multiple exte...

Identifying Successful Learners from Interaction Behaviour

ERIC Educational Resources Information Center

McCuaig, Judi; Baldwin, Julia

2012-01-01

The interaction behaviours of successful, high-achieving learners when using a Learning Management System (LMS) are different than the behaviours of learners who are having more difficulty mastering the course material. This paper explores the idea that conventional Learning Management Systems can exploit data mining techniques to predict the…

Student Interactions in Technology-Rich Classrooms

ERIC Educational Resources Information Center

Fonkert, Karen L.

2010-01-01

Students are more likely to develop a deep conceptual understanding of mathematics when they interact with and discuss their thoughts with others. The National Council of Teachers of Mathematics (NCTM) (1989, 2000) has recommended that students be active learners--communicating with one another, conjecturing, exploring, and justifying claims by…

Regime shifts and panarchies in regional scale social-ecological water systems

PubMed Central

Gunderson, Lance; Cosens, Barbara A.; Chaffin, Brian C.; (Tom) Arnold, Craig A.; Fremier, Alexander K.; Garmestani, Ahjond S.; Craig, Robin Kundis; Gosnell, Hannah; Birge, Hannah E.; Allen, Craig R.; Benson, Melinda H.; Morrison, Ryan R.; Stone, Mark C.; Hamm, Joseph A.; Nemec, Kristine; Schlager, Edella; Llewellyn, Dagmar

2018-01-01

In this article we summarize histories of nonlinear, complex interactions among societal, legal, and ecosystem dynamics in six North American water basins, as they respond to changing climate. These case studies were chosen to explore the conditions for emergence of adaptive governance in heavily regulated and developed social-ecological systems nested within a hierarchical governmental system. We summarize resilience assessments conducted in each system to provide a synthesis and reference by the other articles in this special feature. We also present a general framework used to evaluate the interactions between society and ecosystem regimes and the governance regimes chosen to mediate those interactions. The case studies show different ways that adaptive governance may be triggered, facilitated, or constrained by ecological and/or legal processes. The resilience assessments indicate that complex interactions among the governance and ecosystem components of these systems can produce different trajectories, which include patterns of (a) development and stabilization, (b) cycles of crisis and recovery, which includes lurches in adaptation and learning, and (3) periods of innovation, novelty, and transformation. Exploration of cross scale (Panarchy) interactions among levels and sectors of government and society illustrate that they may constrain development trajectories, but may also provide stability during crisis or innovation at smaller scales; create crises, but may also facilitate recovery; and constrain system transformation, but may also provide windows of opportunity in which transformation, and the resources to accomplish it, may occur. The framework is the starting point for our exploration of how law might play a role in enhancing the capacity of social-ecological systems to adapt to climate change. PMID:29780427

Regime shifts and panarchies in regional scale social-ecological water systems.

PubMed

Gunderson, Lance; Cosens, Barbara A; Chaffin, Brian C; Tom Arnold, Craig A; Fremier, Alexander K; Garmestani, Ahjond S; Craig, Robin Kundis; Gosnell, Hannah; Birge, Hannah E; Allen, Craig R; Benson, Melinda H; Morrison, Ryan R; Stone, Mark C; Hamm, Joseph A; Nemec, Kristine; Schlager, Edella; Llewellyn, Dagmar

2017-03-17

In this article we summarize histories of nonlinear, complex interactions among societal, legal, and ecosystem dynamics in six North American water basins, as they respond to changing climate. These case studies were chosen to explore the conditions for emergence of adaptive governance in heavily regulated and developed social-ecological systems nested within a hierarchical governmental system. We summarize resilience assessments conducted in each system to provide a synthesis and reference by the other articles in this special feature. We also present a general framework used to evaluate the interactions between society and ecosystem regimes and the governance regimes chosen to mediate those interactions. The case studies show different ways that adaptive governance may be triggered, facilitated, or constrained by ecological and/or legal processes. The resilience assessments indicate that complex interactions among the governance and ecosystem components of these systems can produce different trajectories, which include patterns of (a) development and stabilization, (b) cycles of crisis and recovery, which includes lurches in adaptation and learning, and (3) periods of innovation, novelty, and transformation. Exploration of cross scale (Panarchy) interactions among levels and sectors of government and society illustrate that they may constrain development trajectories, but may also provide stability during crisis or innovation at smaller scales; create crises, but may also facilitate recovery; and constrain system transformation, but may also provide windows of opportunity in which transformation, and the resources to accomplish it, may occur. The framework is the starting point for our exploration of how law might play a role in enhancing the capacity of social-ecological systems to adapt to climate change.

Regime shifts and panarchies in regional scale social-ecological water systems

USGS Publications Warehouse

Gunderson, Lance; Cosens, Barbara; Chaffin, Brian C.; Arnold, Craig Anthony (Tony); Fremier, Alexander K.; Garmestani, Ahjond S.; Kundis Craig, Robin; Gosnell, Hannah; Birge, Hannah E.; Allen, Craig R.; Benson, Melinda H.; Morrison, Ryan R.; Stone, Mark; Hamm, Joseph A.; Nemec, Kristine T.; Schlager, Edella; Llewellyn, Dagmar

2017-01-01

In this article we summarize histories of nonlinear, complex interactions among societal, legal, and ecosystem dynamics in six North American water basins, as they respond to changing climate. These case studies were chosen to explore the conditions for emergence of adaptive governance in heavily regulated and developed social-ecological systems nested within a hierarchical governmental system. We summarize resilience assessments conducted in each system to provide a synthesis and reference by the other articles in this special feature. We also present a general framework used to evaluate the interactions between society and ecosystem regimes and the governance regimes chosen to mediate those interactions. The case studies show different ways that adaptive governance may be triggered, facilitated, or constrained by ecological and/or legal processes. The resilience assessments indicate that complex interactions among the governance and ecosystem components of these systems can produce different trajectories, which include patterns of (a) development and stabilization, (b) cycles of crisis and recovery, which includes lurches in adaptation and learning, and (3) periods of innovation, novelty, and transformation. Exploration of cross scale (Panarchy) interactions among levels and sectors of government and society illustrate that they may constrain development trajectories, but may also provide stability during crisis or innovation at smaller scales; create crises, but may also facilitate recovery; and constrain system transformation, but may also provide windows of opportunity in which transformation, and the resources to accomplish it, may occur. The framework is the starting point for our exploration of how law might play a role in enhancing the capacity of social-ecological systems to adapt to climate change.

Exploring the inter-molecular interactions in amyloid-β protofibril with molecular dynamics simulations and molecular mechanics Poisson-Boltzmann surface area free energy calculations.

PubMed

Liu, Fu-Feng; Liu, Zhen; Bai, Shu; Dong, Xiao-Yan; Sun, Yan

2012-04-14

Aggregation of amyloid-β (Aβ) peptides correlates with the pathology of Alzheimer's disease. However, the inter-molecular interactions between Aβ protofibril remain elusive. Herein, molecular mechanics Poisson-Boltzmann surface area analysis based on all-atom molecular dynamics simulations was performed to study the inter-molecular interactions in Aβ(17-42) protofibril. It is found that the nonpolar interactions are the important forces to stabilize the Aβ(17-42) protofibril, while electrostatic interactions play a minor role. Through free energy decomposition, 18 residues of the Aβ(17-42) are identified to provide interaction energy lower than -2.5 kcal/mol. The nonpolar interactions are mainly provided by the main chain of the peptide and the side chains of nine hydrophobic residues (Leu17, Phe19, Phe20, Leu32, Leu34, Met35, Val36, Val40, and Ile41). However, the electrostatic interactions are mainly supplied by the main chains of six hydrophobic residues (Phe19, Phe20, Val24, Met35, Val36, and Val40) and the side chains of the charged residues (Glu22, Asp23, and Lys28). In the electrostatic interactions, the overwhelming majority of hydrogen bonds involve the main chains of Aβ as well as the guanidinium group of the charged side chain of Lys28. The work has thus elucidated the molecular mechanism of the inter-molecular interactions between Aβ monomers in Aβ(17-42) protofibril, and the findings are considered critical for exploring effective agents for the inhibition of Aβ aggregation.

Exploring the inter-molecular interactions in amyloid-β protofibril with molecular dynamics simulations and molecular mechanics Poisson-Boltzmann surface area free energy calculations

NASA Astrophysics Data System (ADS)

Liu, Fu-Feng; Liu, Zhen; Bai, Shu; Dong, Xiao-Yan; Sun, Yan

2012-04-01

Aggregation of amyloid-β (Aβ) peptides correlates with the pathology of Alzheimer's disease. However, the inter-molecular interactions between Aβ protofibril remain elusive. Herein, molecular mechanics Poisson-Boltzmann surface area analysis based on all-atom molecular dynamics simulations was performed to study the inter-molecular interactions in Aβ17-42 protofibril. It is found that the nonpolar interactions are the important forces to stabilize the Aβ17-42 protofibril, while electrostatic interactions play a minor role. Through free energy decomposition, 18 residues of the Aβ17-42 are identified to provide interaction energy lower than -2.5 kcal/mol. The nonpolar interactions are mainly provided by the main chain of the peptide and the side chains of nine hydrophobic residues (Leu17, Phe19, Phe20, Leu32, Leu34, Met35, Val36, Val40, and Ile41). However, the electrostatic interactions are mainly supplied by the main chains of six hydrophobic residues (Phe19, Phe20, Val24, Met35, Val36, and Val40) and the side chains of the charged residues (Glu22, Asp23, and Lys28). In the electrostatic interactions, the overwhelming majority of hydrogen bonds involve the main chains of Aβ as well as the guanidinium group of the charged side chain of Lys28. The work has thus elucidated the molecular mechanism of the inter-molecular interactions between Aβ monomers in Aβ17-42 protofibril, and the findings are considered critical for exploring effective agents for the inhibition of Aβ aggregation.

Urban Space Explorer: A Visual Analytics System for Urban Planning.

PubMed

Karduni, Alireza; Cho, Isaac; Wessel, Ginette; Ribarsky, William; Sauda, Eric; Dou, Wenwen

2017-01-01

Understanding people's behavior is fundamental to many planning professions (including transportation, community development, economic development, and urban design) that rely on data about frequently traveled routes, places, and social and cultural practices. Based on the results of a practitioner survey, the authors designed Urban Space Explorer, a visual analytics system that utilizes mobile social media to enable interactive exploration of public-space-related activity along spatial, temporal, and semantic dimensions.

"Miss, Miss, I've Got a Story!": Exploring Identity through a Micro-Ethnographic Analysis of Lunchtime Interactions with Four Somali Third Grade Students

ERIC Educational Resources Information Center

Kosha, Jean

2013-01-01

This study is an exploration of the ways in which four Somali students use language to express their identity and assert their views. The study explores the ways in which the Somali students' home culture and the school culture influence the development of their identity. Students participated in a lunchtime focus group on a regular basis over a…

Modeling Goal-Directed User Exploration in Human-Computer Interaction

DTIC Science & Technology

2011-02-01

scent, other factors including the layout position and grouping of options in the user-interface also affect user exploration and the likelihood of...grouping of options in the user-interface also affect user exploration and the likelihood of success. This dissertation contributes a new model of goal...better inform UI design. 1.1 RESEARCH GAPS IN MODELING In addition to infoscent, the layout of the UI also affects the choices made during

Twin Brothers with Autism and Their Intra-Pair Interactions in a Pre-School Special Education Class

ERIC Educational Resources Information Center

Markodimitraki, Maria; Ampartzaki, Maria; Kypriotaki, Maria; Linardakis, Michalis

2017-01-01

The present study focused on the intra-pair interaction of a pair of dizygotic twins with autism in pre-school age and explored: (a) the type of play and the level of symbolic play the twins prefer and are most frequently engaged with; (b) the attitudes the twins usually display; (c) the most frequent initiator of interactions; and (d) the way the…

Mobile Gaming and Student Interactions in a Science Center: The Future of Gaming in Science Education

ERIC Educational Resources Information Center

Atwood-Blaine, Dana; Huffman, Douglas

2017-01-01

This article explores the impact of an augmented reality iPad-based mobile game, called The Great STEM Caper, on students' interaction at a science center. An open-source, location-based game platform called ARIS (i.e. Augmented Reality and Interactive Storytelling) was used to create an iPad-based mobile game. The game used QR scan codes and a…

From interaction to interaction: Exploring shared resources constructed through and mediating classroom science learning

NASA Astrophysics Data System (ADS)

Tang, Xiaowei

Recent reform documents and science education literature emphasize the importance of scientific argumentation as a discourse and practice of science that should be supported in school science learning. Much of this literature focuses on the structure of argument, whether for assessing the quality of argument or designing instructional scaffolds. This study challenges the narrowness of this research paradigm and argues for the necessity of examining students' argumentative practices as rooted in the complex, evolving system of the classroom. Employing a sociocultural-historical lens of activity theory (Engestrom, 1987, 1999), discourse analysis is employed to explore how a high school biology class continuously builds affordances and constraints for argumentation practices through interactions. The ways in which argumentation occurs, including the nature of teacher and student participation, are influenced by learning goals, classroom norms, teacher-student relationships and epistemological stances constructed through a class' interactive history. Based on such findings, science education should consider promoting classroom scientific argumentation as a long-term process, requiring supportive resources that develop through continuous classroom interactions. Moreover, in order to understand affordances that support disciplinary learning in classroom, we need to look beyond just disciplinary interactions. This work has implications for classroom research on argumentation and teacher education, specifically, the preparation of teachers for secondary science teaching.

Microscopy of the interacting Harper-Hofstadter model in the few-body limit

NASA Astrophysics Data System (ADS)

Tai, M. Eric; Lukin, Alexander; Rispoli, Matthew; Schittko, Robert; Menke, Tim; Borgnia, Dan; Preiss, Philipp; Grusdt, Fabian; Kaufman, Adam; Greiner, Markus

2017-04-01

The interplay of magnetic fields and interacting particles can lead to exotic phases of matter exhibiting topological order and high degrees of spatial entanglement. While these phases were discovered in a solid-state setting, recent techniques have enabled the realization of gauge fields in systems of ultracold neutral atoms, offering a new experimental paradigm for studying these novel states of matter. This complementary platform holds promise for exploring exotic physics in fractional quantum Hall systems due to the microscopic manipulation and precision possible in cold atom systems. However, these experiments thus far have mostly explored the regime of weak interactions. Here, we show how strong interactions can modify the propagation of particles in a 2 × N , real-space ladder governed by the Harper-Hofstadter model. We observe inter-particle interactions affect the populating of chiral bands, giving rise to chiral dynamics whose multi-particle correlations indicate both bound and free-particle character. The novel form of interaction-induced chirality observed in these experiments demonstrates the essential ingredients for future investigations of highly entangled topological phases of many-body systems. We are supported by Grants from the National Science Foundation, Gordon and Betty Moore Foundation's EPiQS Initiative, an Air Force Office of Scientific Research MURI program, an Army Research Office MURI program, and the NSF GRFP (MNR).

CrosstalkNet: A Visualization Tool for Differential Co-expression Networks and Communities.

PubMed

Manem, Venkata; Adam, George Alexandru; Gruosso, Tina; Gigoux, Mathieu; Bertos, Nicholas; Park, Morag; Haibe-Kains, Benjamin

2018-04-15

Variations in physiological conditions can rewire molecular interactions between biological compartments, which can yield novel insights into gain or loss of interactions specific to perturbations of interest. Networks are a promising tool to elucidate intercellular interactions, yet exploration of these large-scale networks remains a challenge due to their high dimensionality. To retrieve and mine interactions, we developed CrosstalkNet, a user friendly, web-based network visualization tool that provides a statistical framework to infer condition-specific interactions coupled with a community detection algorithm for bipartite graphs to identify significantly dense subnetworks. As a case study, we used CrosstalkNet to mine a set of 54 and 22 gene-expression profiles from breast tumor and normal samples, respectively, with epithelial and stromal compartments extracted via laser microdissection. We show how CrosstalkNet can be used to explore large-scale co-expression networks and to obtain insights into the biological processes that govern cross-talk between different tumor compartments. Significance: This web application enables researchers to mine complex networks and to decipher novel biological processes in tumor epithelial-stroma cross-talk as well as in other studies of intercompartmental interactions. Cancer Res; 78(8); 2140-3. ©2018 AACR . ©2018 American Association for Cancer Research.

Dynamic near-field optical interaction between oscillating nanomechanical structures

DOE PAGES

Ahn, Phillip; Chen, Xiang; Zhang, Zhen; ...

2015-05-27

Near-field optical techniques exploit light-matter interactions at small length scales for mechanical sensing and actuation of nanomechanical structures. Here, we study the optical interaction between two mechanical oscillators—a plasmonic nanofocusing probe-tip supported by a low frequency cantilever, and a high frequency nanomechanical resonator—and leverage their interaction for local detection of mechanical vibrations. The plasmonic nanofocusing probe provides a confined optical source to enhance the interaction between the two oscillators. Dynamic perturbation of the optical cavity between the probe-tip and the resonator leads to nonlinear modulation of the scattered light intensity at the sum and difference of their frequencies. This double-frequencymore » demodulation scheme is explored to suppress unwanted background and to detect mechanical vibrations with a minimum detectable displacement sensitivity of 0.45pm/Hz 1/2, which is limited by shot noise and electrical noise. We explore the demodulation scheme for imaging the bending vibration mode shape of the resonator with a lateral spatial resolution of 20nm. We also demonstrate the time-resolved aspect of the local optical interaction by recording the ring-down vibrations of the resonator at frequencies of up to 129MHz. The near-field optical technique is promising for studying dynamic mechanical processes in individual nanostructures.« less

Assessment of genetic and nongenetic interactions for the prediction of depressive symptomatology: an analysis of the Wisconsin Longitudinal Study using machine learning algorithms.

PubMed

Roetker, Nicholas S; Page, C David; Yonker, James A; Chang, Vicky; Roan, Carol L; Herd, Pamela; Hauser, Taissa S; Hauser, Robert M; Atwood, Craig S

2013-10-01

We examined depression within a multidimensional framework consisting of genetic, environmental, and sociobehavioral factors and, using machine learning algorithms, explored interactions among these factors that might better explain the etiology of depressive symptoms. We measured current depressive symptoms using the Center for Epidemiologic Studies Depression Scale (n = 6378 participants in the Wisconsin Longitudinal Study). Genetic factors were 78 single nucleotide polymorphisms (SNPs); environmental factors-13 stressful life events (SLEs), plus a composite proportion of SLEs index; and sociobehavioral factors-18 personality, intelligence, and other health or behavioral measures. We performed traditional SNP associations via logistic regression likelihood ratio testing and explored interactions with support vector machines and Bayesian networks. After correction for multiple testing, we found no significant single genotypic associations with depressive symptoms. Machine learning algorithms showed no evidence of interactions. Naïve Bayes produced the best models in both subsets and included only environmental and sociobehavioral factors. We found no single or interactive associations with genetic factors and depressive symptoms. Various environmental and sociobehavioral factors were more predictive of depressive symptoms, yet their impacts were independent of one another. A genome-wide analysis of genetic alterations using machine learning methodologies will provide a framework for identifying genetic-environmental-sociobehavioral interactions in depressive symptoms.

The experiences of undergraduate nursing students with bots in Second LifeRTM

NASA Astrophysics Data System (ADS)

Rose, Lesele H.

As technology continues to transform education from the status quo of traditional lecture-style instruction to an interactive engaging learning experience, students' experiences within the learning environment continues to change as well. This dissertation addressed the need for continuing research in advancing implementation of technology in higher education. The purpose of this phenomenological study was to discover more about the experiences of undergraduate nursing students using standardized geriatric evaluation tools when interacting with scripted geriatric patient bots tools in a simulated instructional intake setting. Data was collected through a Demographics questionnaire, an Experiential questionnaire, and a Reflection questionnaire. Triangulation of data collection occurred through an automatically created log of the interactions with the two bots, and by an automatically recorded log of the participants' movements while in the simulated geriatric intake interview. The data analysis consisted of an iterative review of the questionnaires and the participants' logs in an effort to identify common themes, recurring comments, and issues which would benefit from further exploration. Findings revealed that the interactions with the bots were perceived as a valuable experience for the participants from the perspective of interacting with the Geriatric Evaluation Tools in the role of an intake nurse. Further research is indicated to explore instructional interactions with bots in effectively mastering the use of established Geriatric Evaluation Tools.

The 1-ethyl-3-methylimidazolium bis(trifluoro-methylsulfonyl)-imide ionic liquid nanodroplets on solid surfaces and in electric field: A molecular dynamics simulation study

NASA Astrophysics Data System (ADS)

Dong, Dengpan; Vatamanu, Jenel P.; Wei, Xiaoyu; Bedrov, Dmitry

2018-05-01

Atomistic molecular dynamics simulations were conducted to study the wetting states of 1-ethyl-3-methylimidazolium bis(trifluoro-methylsulfonyl)-imide ionic liquid (IL) nanodroplets on surfaces with different strengths of van der Waals (VDW) interactions and in the presence of an electric field. By adjusting the depth of Lennard-Jones potential, the van der Waals interaction between the solid surface and ionic liquid was systematically varied. The shape of the droplets was analyzed to extract the corresponding contact angle utilized to characterize wetting states of the nanodroplets. The explored range of surface-IL interactions allowed contact angles ranging from complete IL spreading on the surface to poor wettability. The effect of the external electrical field was explored by adding point charges to the surface atoms. Systems with two charge densities (±0.002 e/atom and ±0.004 e/atom) that correspond to 1.36 V/nm and 2.72 V/nm electric fields were investigated. Asymmetrical wetting states were observed for both cases. At 1.36 V/nm electric field, contributions of IL-surface VDW interactions and Coulombic interactions to the wetting state were competitive. At 2.72 V/nm field, electrostatic interactions dominate the interaction between the nanodroplet and surface, leading to enhanced wettability on all surfaces.

Interspecies interactions that result in Bacillus subtilis forming biofilms are mediated mainly by members of its own genus.

PubMed

Shank, Elizabeth A; Klepac-Ceraj, Vanja; Collado-Torres, Leonardo; Powers, Gordon E; Losick, Richard; Kolter, Roberto

2011-11-29

Many different systems of bacterial interactions have been described. However, relatively few studies have explored how interactions between different microorganisms might influence bacterial development. To explore such interspecies interactions, we focused on Bacillus subtilis, which characteristically develops into matrix-producing cannibals before entering sporulation. We investigated whether organisms from the natural environment of B. subtilis--the soil--were able to alter the development of B. subtilis. To test this possibility, we developed a coculture microcolony screen in which we used fluorescent reporters to identify soil bacteria able to induce matrix production in B. subtilis. Most of the bacteria that influence matrix production in B. subtilis are members of the genus Bacillus, suggesting that such interactions may be predominantly with close relatives. The interactions we observed were mediated via two different mechanisms. One resulted in increased expression of matrix genes via the activation of a sensor histidine kinase, KinD. The second was kinase independent and conceivably functions by altering the relative subpopulations of B. subtilis cell types by preferentially killing noncannibals. These two mechanisms were grouped according to the inducing strain's relatedness to B. subtilis. Our results suggest that bacteria preferentially alter their development in response to secreted molecules from closely related bacteria and do so using mechanisms that depend on the phylogenetic relatedness of the interacting bacteria.

Co-Construction in Korean Interaction

ERIC Educational Resources Information Center

Ju, Hee

2011-01-01

This dissertation explores co-construction of a situated activity in a current unit by mainly focusing on hearers' actions. The "co-construction" involves a process of interaction in which speakers and hearers jointly construct the form and the meaning of ongoing utterances even when they disagree with each other (Jacoby & Ochs,…

Inter- and Intrafamily Interaction in Multifamily Group Therapy.

ERIC Educational Resources Information Center

Gould, Edward; DeGroot, Donald

1981-01-01

Studied how family members utilized the intrafamily interaction more than the interfamily mode. With the interfamily mode, either mothers or fathers tended to dominate. When dominant, mothers talked more to other mothers, while fathers talked mostly to children or fathers. Explored the possible significance of shifting parental dominance patterns.…

Emerging Affordances in Videoconferencing for Language Learning and Teaching

ERIC Educational Resources Information Center

Dey-Plissonneau, Aparajita

2017-01-01

The theory of affordances (Gibson, 1977) came into focus in humancomputer interactions and ecological interactive design to explore design strategies to support the actor in direct perception of action possibilities in the operation of things. However, few studies have analysed the basis of affordances in the cultural-historical development of…

Practice and Reflection on Interactive Three-Dimensional Teaching System in Agricultural and Forestry Colleges

ERIC Educational Resources Information Center

Lei, Zhimin

2013-01-01

Ever since the new curriculum was implemented, Sichuan Agricultural University that is characterized by agricultural science has conducted ideological and political teaching reform, explored a basic route to integrate scientific outlook on development into theoretical teaching and initially formed a human-oriented interactive three-dimensional…

An Investigation of Interactive, Dialogue-Based Instruction for Undergraduate Art History

ERIC Educational Resources Information Center

Gioffre, Penelope

2012-01-01

This paper explores the feasibility and efficacy of incorporating an interactive, discussion-based instructional approach into an undergraduate art history survey course and investigates effects of the new pedagogic strategy on students' demonstrated comprehension and retention of required content. The action research project follows a systematic…

The Dynamics of Social Interaction in Telecollaborative Tandem Exchanges

ERIC Educational Resources Information Center

Janssen Sanchez, Brianna

2015-01-01

Using both quantitative and qualitative methods of inquiry, this dissertation study undertakes an exploration of the dynamics of the social interaction in discourse co-constructed by pairs of college students in telecollaborative tandem exchanges. Two groups of participants, Mexican learners of English as a foreign language and American learners…

The Influence of Learner Characteristics on Satisfaction with Interactive Televised Courses in Florida Community Colleges.

ERIC Educational Resources Information Center

Bower, Beverly L.; Kamata, Akihito; Smith, Kathleen Shea

This report describes a pilot project designed to explore the influence of particular personality and demographic characteristics on community college student satisfaction with distance learning, specifically interactive telecommunications (ITV) courses. The study used the Telecourse Evaluation Questionnaire (TEQ) and the Sixteen Personality…

Vision and Embodied Knowing: The Making of Floral Design

ERIC Educational Resources Information Center

Gåfvels, Camilla

2016-01-01

This article focuses on assessment actions in floristry education, addressing how interaction with flowers influences and mediates vocational knowing. Using video recordings from floristry education for adults, the article explores the interaction between teacher and student when assessing on-going work and performance as a way to frame the…

Productive Mess: First-Year Composition Takes the University's Agonism Online

ERIC Educational Resources Information Center

Rivers, Nathaniel A.; Santos, Marc C.; Weber, Ryan P.

2009-01-01

This webtext describes a pilot course that united four first-year composition courses around shared readings and online discussion addressing the physical and virtual university. The goal of the pilot was to foster previously impossible student interactions by exploring how discrete discussion roles shaped interaction and reputations among…

Cultivar-dependent root colonization, antifungal metabolite accumulation and gene expression in the wheat-Pseudomonas interaction

USDA-ARS?s Scientific Manuscript database

We explored the role of host genotype in three aspects of the wheat-Pseudomonas biocontrol interaction: rhizosphere population density, accumulation of rhizosphere 2,4-diacetylphloroglucinol (DAPG), and Pseudomonas-mediated changes in root gene expression. Wheat cultivars varied in ability to suppo...

A Worldwide Intercultural Network: Exploring Electronic Messaging for Instruction. Interactive Technology Laboratory Report #8.

ERIC Educational Resources Information Center

Cohen, Moshe; Miyake, Naomi

A worldwide international computer network, called the Intercultural Learning Network, has been developed to provide students from different cultures with opportunities to work cooperatively. Prototype activities have been developed and tested which facilitate and contextualize interactions among secondary and college students. Joint projects in…

Structured Dialogue Design in LAMS through Interactive Lecture Podcasting

ERIC Educational Resources Information Center

Dobozy, Eva

2011-01-01

This paper explores the utility of interactive lecture podcasting in LAMS and the impact of structured dialogue design. It reports how curriculum renewal and innovation were greeted with scepticism by teacher education students enrolled in a compulsory curriculum unit at an Australian university. An analytic induction methodology in conjunction…

imDEV: a graphical user interface to R multivariate analysis tools in Microsoft Excel

USDA-ARS?s Scientific Manuscript database

Interactive modules for data exploration and visualization (imDEV) is a Microsoft Excel spreadsheet embedded application providing an integrated environment for the analysis of omics data sets with a user-friendly interface. Individual modules were designed to provide toolsets to enable interactive ...

Interactive Video in the Special Classroom: A Pilot Study.

ERIC Educational Resources Information Center

Browning, Philip; And Others

1986-01-01

Describes a courseware development project at the University of Oregon which explored use of interactive video with mentally disabled students to teach life enhancement skills. Discussion of the results of a pilot study of one of the modules includes information on student achievement and teacher and student reactions. (MBR)

Relationship-Based Developmentally Supportive Approach to Infant Childcare Practice

ERIC Educational Resources Information Center

Kim, Yunhee

2016-01-01

Caregivers' warm, sensitive, and attentive interactions with their children have been widely considered key indicators of infant-caregiver interaction quality in childcare contexts. The primary purpose of this study was to explore infant's daily experiences and the characteristics of relationship-based supportive care practices in a childcare…

Useful Pedagogies or Financial Hardships? Interactive Response Technology (Clickers) in the Large College Classroom

ERIC Educational Resources Information Center

Boatright-Horowitz, Su L.

2009-01-01

Interactive response systems "clickers" can provide multiple benefits to the students and faculty who use them, including immediate performance feedback and greater student engagement in learning. My own exploration of this technology has yielded five pedagogically different types of polling questions, specifically measurement of student…

Touching Practice and Physical Education: Deconstruction of a Contemporary Moral Panic

ERIC Educational Resources Information Center

Fletcher, Simon

2013-01-01

This paper explores the insecurities and discursive moral panics elicited by the discussion of intergenerational touch in education, and their subsequent manifestation in "classroom panopticism". In a number of contexts, public hysteria has grown around the interaction between adult and child, and whether this interaction stays within…

Ethical Concerns: Negotiating Truth and Trust

ERIC Educational Resources Information Center

McGarvey, Lynn M.; Sterenberg, Gladys

2009-01-01

Few studies in mathematics education explicitly address ethical issues arising from student interactions. The ethical concerns held by students are expressed in their words, actions, and interactions. The purpose of this article is to explore the ethical nature of copying as it arises in a mathematics classroom. We investigate the basis for…

An Evaluation of Multimodal Interactions with Technology while Learning Science Concepts

ERIC Educational Resources Information Center

Anastopoulou, Stamatina; Sharples, Mike; Baber, Chris

2011-01-01

This paper explores the value of employing multiple modalities to facilitate science learning with technology. In particular, it is argued that when multiple modalities are employed, learners construct strong relations between physical movement and visual representations of motion. Body interactions with visual representations, enabled by…

Exploring Matter: An Interactive, Inexpensive Chemistry Exhibit for Museums

ERIC Educational Resources Information Center

Murov, Steven; Chavez, Arnold

2017-01-01

Despite its vital importance in our lives, chemistry is inadequately represented in most museums. Issues such as safety, replenishing and disposal of chemicals, supervision required, and cost are constraints that have limited the number and size of chemistry exhibits. Taking into account the constraints, a 21-station interactive and inexpensive…

Managing Anxiety: A Case Study of an International Teaching Assistant's Interaction with American Students

ERIC Educational Resources Information Center

Zhou, Ji

2014-01-01

This case study utilizes structuration theory to explore the complexities in the academic interaction between a Chinese international teaching assistant (ITA) and her American students. Through four semi-structured participant interviews, eight classroom observations, and student feedback, major themes and variations were identified regarding the…

Goals, Big and Small

ERIC Educational Resources Information Center

Walkow, Martin

2012-01-01

This dissertation explores the interaction of syntax and morphology in the morphological realization of AGREE-relations. I present two case studies of derivational interactions of AGREE-processes where the morphological realization of the later processes are affected by the earlier ones. The two cases studied differ in the way probes and goals…

Exploring whether and how ants affect reproductive fitness in Senna mexicana var. chapmanii

USDA-ARS?s Scientific Manuscript database

Extrafloral nectar (EFN) mediates food-for-protection mutualisms between plants and ants. Ant-plant mutualisms are keystone associations, occurring within a complex web of biotic interactions. As such, these interactions may affect plant fitness in a number of ways, both positive and negative. In S...

Exploring plant root traits and fungal interactions governing plant community structure: Re-focusing long standing questions.

USDA-ARS?s Scientific Manuscript database

Resource availability has long been recognized for playing a major role in structuring plant communities. Nonetheless, a functional understanding of root traits and interactions with soil organisms involved in acquiring those resources has largely remained out of focus and outside mainstream ecolog...

Integration of Interactive Whiteboard in Swedish Preschool Practices

ERIC Educational Resources Information Center

Bourbour, Maryam; Vigmo, Sylvi; Samuelsson, Ingrid Pramling

2015-01-01

This paper aims at exploring the roles preschool teachers give technologies in mathematics education and the ways they structure their mathematics learning activities using interactive whiteboard (IWB) as a technological artefact. Data collected from observations of three preschool teachers embedding IWB in a preschool practice in Sweden provided…

Mapping Languaging in Digital Spaces: Literacy Practices at Borderlands

ERIC Educational Resources Information Center

Dahlberg, Giulia Messina; Bagga-Gupta, Sangeeta

2016-01-01

The study presented in this article explores the ways in which discursive-technologies shape interaction in "digitally-mediated" educational settings in terms of affordances and constraints for the participants. Our multi-scale sociocultural-dialogical analysis of the interactional order in the online sessions of an "Italian for…

Using Interactive Software to Teach Foundational Mathematical Skills

ERIC Educational Resources Information Center

Lysenko, Larysa; Rosenfield, Steven; Dedic, Helena; Savard, Annie; Idan, Einat; Abrami, Philip C.; Wade, C. Anne; Naffi, Nadia

2016-01-01

The pilot research presented here explores the classroom use of Emerging Literacy in Mathematics (ELM) software, a research-based bilingual interactive multimedia instructional tool, and its potential to develop emerging numeracy skills. At the time of the study, a central theme of early mathematics curricula, "Number Concept," was fully…

Nonfiction Reading Comprehension in Middle School: Exploring in Interactive Software Approach

ERIC Educational Resources Information Center

Wolff, Evelyn S.; Isecke, Harriet; Rhoads, Christopher; Madura, John P.

2013-01-01

The struggles of students in the United States to comprehend non-fiction science text are well documented. Middle school students, in particular, have minimal instruction in comprehending nonfiction and flounder on assessments. This article describes the development process of the Readorium software, an interactive web-based program being…

Social Interactions in Online Gaming

ERIC Educational Resources Information Center

Griffiths, Mark; Hussain, Zaheer; Grüsser, Sabine M.; Thalemann, Ralf; Cole, Helena; Davies, Mark N. O.; Chappell, Darren

2011-01-01

This paper briefly overviews five studies examining massively multiplayer online role-playing games (MMORPGs). The first study surveyed 540 gamers and showed that the social aspects of the game were the most important factor for many gamers. The second study explored the social interactions of 912 MMORPG players and showed they created strong…

Enabling Accessibility Through Model-Based User Interface Development.

PubMed

Ziegler, Daniel; Peissner, Matthias

2017-01-01

Adaptive user interfaces (AUIs) can increase the accessibility of interactive systems. They provide personalized display and interaction modes to fit individual user needs. Most AUI approaches rely on model-based development, which is considered relatively demanding. This paper explores strategies to make model-based development more attractive for mainstream developers.

Beginning Learners' Development of Interactional Competence: Alignment Activity

ERIC Educational Resources Information Center

Tecedor, Marta

2016-01-01

This study examined the development of interactional competence (Hall, 1993; He & Young, 1998) by beginning learners of Spanish as indexed by their use of alignment moves. Discourse analysis techniques and quantitative data analysis were used to explore how 52 learners expressed alignment and changes in participation patterns in two sets of…

Multilingual Institutional Discourses of Negotiation and Intertextuality in Writing Center Interactions in Macao

ERIC Educational Resources Information Center

Lee, Alice Shu-Ju

2017-01-01

This dissertation explores the identity enactments (Bucholtz & Hall, 2005) of 14 multilingual university writing center tutors and multilingual student writers who use English and Putonghua to negotiate their interactions. The study is situated within sociocultural theory (Vygotsky, 1978) and uses ethnographic methods such as observation,…

Change Process in Organizations [in HRD].

ERIC Educational Resources Information Center

1995

These four papers are from a symposium that was facilitated by Toni Powell on the change process in organizations at the 1995 Academy of Human Resource Development (HRD) conference. "The Effectiveness of Change Agents as Affected by Strategic Interactions" (Marie A. George) explores the nature of strategic interactions exhibited by a chief…

Task Complexity, Learning Opportunities, and Korean EFL Learners' Question Development

ERIC Educational Resources Information Center

Kim, YouJin

2012-01-01

Building on the cognitive and interactive perspectives of task research, the cognition hypothesis states that increasing task complexity promotes greater interaction and feedback and thus facilitates second language (L2) development (Robinson, 2001b, 2007a). To date, very little research has explored this claim during learner-learner interactions…

Transmuting Common Substances: The Cold Fusion Controversy and the Rhetoric of Science.

ERIC Educational Resources Information Center

Thacker, Brad; Stratman, James F.

1995-01-01

Explores the relationship among forensic, deliberative, and epideictic modes of rhetoric in the cold fusion controversy. Shows the interactions between three modes of rhetoric. Examines the ways in which the modes have shaped the emerging scientific consensus. Supports Robert Sanders' contention that rhetorical practices interact with scientific…

Can Functional Brain Imaging Be Used to Explore Interactivity and Cognition in Multimedia Learning Environments?

ERIC Educational Resources Information Center

Dalgarno, Barney; Kennedy, Gregor; Bennett, Sue

2010-01-01

This paper reviews existing methods used to address questions about interactivity, cognition and learning in multimedia learning environments. Existing behavioural and self-report methods identified include observations, audit trails, questionnaires, interviews, video-stimulated recall, and think-aloud protocols. The limitations of these methods…

Interaction Patterns in Synchronous Online Calculus and Linear Algebra Recitations

ERIC Educational Resources Information Center

Mayer, Greg; Hendricks, Cher

2014-01-01

This study describes interaction patterns observed during a pilot project that explored the use of web-conferencing (WC) software in two undergraduate distance education courses offered to advanced high-school students. The pilot program replaced video-conferencing technology with WC software during recitations, so as to increase participation in…

Impacts of Future Climate, Emission, and Land Use Changes on Aerosols and Air Quality over the Continental

EPA Science Inventory

Changes in climate, emission, and land use in the U.S. over the next century are imminent. The response of geologic, biogenic, and anthropogenic aerosol to interactions between these changes, however, are more uncertain and difficult to quantify. To explore these interactions, ...

Interactive Digital Textbooks and Engagement: A Learning Strategies Framework

ERIC Educational Resources Information Center

Bikowski, Dawn; Casal, J. Elliott

2018-01-01

This mixed-methods study explored non-native English speaking students' learning processes and engagement as they used a customized interactive digital textbook housed on a mobile device. Think aloud protocols, surveys of anticipated and actual engagement with the digital textbook, reflective journals, and member checking constituted data…

Learners' Internal Management of Cognitive Processing in Online Learning

ERIC Educational Resources Information Center

Chen, C.-Y.; Pedersen, S.

2012-01-01

This study examined students' internal management of their cognitive processing in an interactive online class. A mixed methods approach was used to explore students' strategy use in online discussions. The focus is on examining individual knowledge construction through active cognitive engagement, rather than the social interactions, in the…

An Interaction Analysis of Self-Disclosure.

ERIC Educational Resources Information Center

Hancock, Brenda Robinson

This study explored whether an interaction analysis of ongoing communication can be useful in describing the process of self-disclosure. Eight women were assigned to dyads: two acquaintance dyads (subjects were acquainted through a small class in communication and had known each other for two months), and two friendship dyads (subjects had been…

Play Behaviors of Parents and Their Young Children with Disabilities

ERIC Educational Resources Information Center

Childress, Dana C.

2011-01-01

Learning to explore, communicate, and interact with others and the environment through play can be problematic for young children with disabilities, but with parental support, children can learn and interact successfully during play activities. To determine how parents engage their preschool children with disabilities in play and what behaviors…

Learner Attention to Form in ACCESS Task-Based Interaction

ERIC Educational Resources Information Center

Dao, Phung; Iwashita, Noriko; Gatbonton, Elizabeth

2017-01-01

This study explored the potential effects of communicative tasks developed using a reformulation of a task-based language teaching called Automatization in Communicative Contexts of Essential Speech Sequences (ACCESS) that includes automatization of language elements as one of its goals on learner attention to form in task-based interaction. The…

Mobile Learning in Distance Education: Utility or Futility?

ERIC Educational Resources Information Center

Koole, Marguerite; McQuilkin, Janice Letkeman; Ally, Mohamed

2010-01-01

Can mobile technology improve flexibility and quality of interaction for graduate students in distance programs? This paper reports the results of an innovative study exploring the usability, learning, and social interaction of mobile access to online course materials at a Canadian distance education university. Through a system called MobiGlam,…

Theoretical study of interactions between 2,2-Bis (ethylferrocenyl) propane and ammonium perchlorate at low temperature

NASA Astrophysics Data System (ADS)

Zhou, Junhong; Zhang, Wei; Yang, Jun; Jiang, Benzheng; Chen, Weiming

2016-05-01

In order to explore the interaction mechanism between 2,2-Bis (ethylferrocenyl) propane (GFP) and ammonium perchlorate (AP) at low temperature (below 250 °C), all the possible intermolecular interactions between GFP and AP were calculated. The calculations were performed in single molecule, cluster and slab models. The calculation results show that the interactions between GFP and AP at low temperature mainly come from GFP:-H+ and GFP-NH4+ pair interactions. We speculate that the interaction mechanism between GFP and AP at low temperature is that GFP/H+ or GFP/NH4+ interactions cause GFP to be protonated, and then protonated GFP is to further oxidized.

ShapeShop: Towards Understanding Deep Learning Representations via Interactive Experimentation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hohman, Frederick M.; Hodas, Nathan O.; Chau, Duen Horng

Deep learning is the driving force behind many recent technologies; however, deep neural networks are often viewed as “black-boxes” due to their internal complexity that is hard to understand. Little research focuses on helping people explore and understand the relationship between a user’s data and the learned representations in deep learning models. We present our ongoing work, ShapeShop, an interactive system for visualizing and understanding what semantics a neural network model has learned. Built using standard web technologies, ShapeShop allows users to experiment with and compare deep learning models to help explore the robustness of image classifiers.

My Ideal City (mic): Virtual Environments to Design the Future Town

NASA Astrophysics Data System (ADS)

Borgherini, M.; Garbin, E.

2011-09-01

MIC is an EU funded project to explore the use of shared virtual environments as part of a public discussion on the issues of building the city of the future. An interactive exploration of four european cities - in the digital city models were translated urban places, family problems and citizens wishes - is a chance to see them in different ways and from different points of view, to imagine new scenarios to overcome barriers and stereotypes no longer effective. This paper describes the process from data to visualization of virtual cities and, in detail, the project of two interactive digital model (Trento and Lisbon).

The Formation of Filamentary Structures in Radiative Cluster Winds

NASA Astrophysics Data System (ADS)

Rodríguez-González, Ary; Esquivel, Alejandro; Raga, Alejandro C.; Cantó, Jorge

We explore the dynamics of a "cluster wind" flow in the regime in which the shocks resulting from the interaction of winds from nearby stars are radiative. We show that for a cluster with low-intermedia mass stars, the wind interactions are indeed likely to be radiative. We then compute three dimensional, radiative simulations of a cluster of 75 young stars, exploring the effects of varying the wind parameters and the density of the initial ISM that permeates the volume of the cluster. These simulations show that the ISM is compressed by the action of the winds into a structure of dense knots and filaments.

Coaching the exploration and exploitation in active learning for interactive video retrieval.

PubMed

Wei, Xiao-Yong; Yang, Zhen-Qun

2013-03-01

Conventional active learning approaches for interactive video/image retrieval usually assume the query distribution is unknown, as it is difficult to estimate with only a limited number of labeled instances available. Thus, it is easy to put the system in a dilemma whether to explore the feature space in uncertain areas for a better understanding of the query distribution or to harvest in certain areas for more relevant instances. In this paper, we propose a novel approach called coached active learning that makes the query distribution predictable through training and, therefore, avoids the risk of searching on a completely unknown space. The estimated distribution, which provides a more global view of the feature space, can be used to schedule not only the timing but also the step sizes of the exploration and the exploitation in a principled way. The results of the experiments on a large-scale data set from TRECVID 2005-2009 validate the efficiency and effectiveness of our approach, which demonstrates an encouraging performance when facing domain-shift, outperforms eight conventional active learning methods, and shows superiority to six state-of-the-art interactive video retrieval systems.

Mathematical and computational approaches can complement experimental studies of host-pathogen interactions.

PubMed

Kirschner, Denise E; Linderman, Jennifer J

2009-04-01

In addition to traditional and novel experimental approaches to study host-pathogen interactions, mathematical and computer modelling have recently been applied to address open questions in this area. These modelling tools not only offer an additional avenue for exploring disease dynamics at multiple biological scales, but also complement and extend knowledge gained via experimental tools. In this review, we outline four examples where modelling has complemented current experimental techniques in a way that can or has already pushed our knowledge of host-pathogen dynamics forward. Two of the modelling approaches presented go hand in hand with articles in this issue exploring fluorescence resonance energy transfer and two-photon intravital microscopy. Two others explore virtual or 'in silico' deletion and depletion as well as a new method to understand and guide studies in genetic epidemiology. In each of these examples, the complementary nature of modelling and experiment is discussed. We further note that multi-scale modelling may allow us to integrate information across length (molecular, cellular, tissue, organism, population) and time (e.g. seconds to lifetimes). In sum, when combined, these compatible approaches offer new opportunities for understanding host-pathogen interactions.

Young macaques (Macaca fascicularis) preferentially bias attention towards closer, older, and better tool users.

PubMed

Tan, Amanda W Y; Hemelrijk, Charlotte K; Malaivijitnond, Suchinda; Gumert, Michael D

2018-05-12

Examining how animals direct social learning during skill acquisition under natural conditions, generates data for examining hypotheses regarding how transmission biases influence cultural change in animal populations. We studied a population of macaques on Koram Island, Thailand, and examined model-based biases during interactions by unskilled individuals with tool-using group members. We first compared the prevalence of interactions (watching, obtaining food, object exploration) and proximity to tool users during interactions, in developing individuals (infants, juveniles) versus mature non-learners (adolescents, adults), to provide evidence that developing individuals are actively seeking information about tool use from social partners. All infants and juveniles, but only 49% of mature individuals carried out interacted with tool users. Macaques predominantly obtained food by scrounging or stealing, suggesting maximizing scrounging opportunities motivates interactions with tool users. However, while interactions by adults was limited to obtaining food, young macaques and particularly infants also watched tool users and explored objects, indicating additional interest in tool use itself. We then ran matrix correlations to identify interaction biases, and what attributes of tool users influenced these. Biases correlated with social affiliation, but macaques also preferentially targeted tool users that potentially increase scrounging and learning opportunities. Results suggest that social structure may constrain social learning, but the motivation to bias interactions towards tool users to maximize feeding opportunities may also socially modulate learning by facilitating close proximity to better tool users, and further interest in tool-use actions and materials, especially during development.

Dependence of Interaction Free Energy between Solutes on an External Electrostatic Field

PubMed Central

Yang, Pei-Kun

2013-01-01

To explore the athermal effect of an external electrostatic field on the stabilities of protein conformations and the binding affinities of protein-protein/ligand interactions, the dependences of the polar and hydrophobic interactions on the external electrostatic field, −Eext, were studied using molecular dynamics (MD) simulations. By decomposing Eext into, along, and perpendicular to the direction formed by the two solutes, the effect of Eext on the interactions between these two solutes can be estimated based on the effects from these two components. Eext was applied along the direction of the electric dipole formed by two solutes with opposite charges. The attractive interaction free energy between these two solutes decreased for solutes treated as point charges. In contrast, the attractive interaction free energy between these two solutes increased, as observed by MD simulations, for Eext = 40 or 60 MV/cm. Eext was applied perpendicular to the direction of the electric dipole formed by these two solutes. The attractive interaction free energy was increased for Eext = 100 MV/cm as a result of dielectric saturation. The force on the solutes along the direction of Eext computed from MD simulations was greater than that estimated from a continuum solvent in which the solutes were treated as point charges. To explore the hydrophobic interactions, Eext was applied to a water cluster containing two neutral solutes. The repulsive force between these solutes was decreased/increased for Eext along/perpendicular to the direction of the electric dipole formed by these two solutes. PMID:23852018

The Hologram in My Hand: How Effective is Interactive Exploration of 3D Visualizations in Immersive Tangible Augmented Reality?

PubMed

Bach, Benjamin; Sicat, Ronell; Beyer, Johanna; Cordeil, Maxime; Pfister, Hanspeter

2018-01-01

We report on a controlled user study comparing three visualization environments for common 3D exploration. Our environments differ in how they exploit natural human perception and interaction capabilities. We compare an augmented-reality head-mounted display (Microsoft HoloLens), a handheld tablet, and a desktop setup. The novel head-mounted HoloLens display projects stereoscopic images of virtual content into a user's real world and allows for interaction in-situ at the spatial position of the 3D hologram. The tablet is able to interact with 3D content through touch, spatial positioning, and tangible markers, however, 3D content is still presented on a 2D surface. Our hypothesis is that visualization environments that match human perceptual and interaction capabilities better to the task at hand improve understanding of 3D visualizations. To better understand the space of display and interaction modalities in visualization environments, we first propose a classification based on three dimensions: perception, interaction, and the spatial and cognitive proximity of the two. Each technique in our study is located at a different position along these three dimensions. We asked 15 participants to perform four tasks, each task having different levels of difficulty for both spatial perception and degrees of freedom for interaction. Our results show that each of the tested environments is more effective for certain tasks, but that generally the desktop environment is still fastest and most precise in almost all cases.

Computer Interactives for the Mars Atmospheric and Volatile Evolution (MAVEN) Mission through NASA's "Project Spectra!"

NASA Astrophysics Data System (ADS)

Wood, E. L.

2014-12-01

"Project Spectra!" is a standards-based E-M spectrum and engineering program that includes paper and pencil activities as well as Flash-based computer games that help students solidify understanding of high-level planetary and solar physics. Using computer interactive games, students experience and manipulate information making abstract concepts accessible, solidifying understanding and enhancing retention of knowledge. Since students can choose what to watch and explore, the interactives accommodate a broad range of learning styles. Students can go back and forth through the interactives if they've missed a concept or wish to view something again. In the end, students are asked critical thinking questions and conduct web-based research. As part of the Mars Atmospheric and Volatile EvolutioN (MAVEN) mission education programming, we've developed two new interactives. The MAVEN mission will study volatiles in the upper atmosphere to help piece together Mars' climate history. In the first interactive, students explore black body radiation, albedo, and a simplified greenhouse effect to establish what factors contribute to overall planetary temperature. Students design a planet that is able to maintain liquid water on the surface. In the second interactive, students are asked to consider conditions needed for Mars to support water on the surface, keeping some variables fixed. Ideally, students will walk away with the very basic and critical elements required for climate studies, which has far-reaching implications beyond the study of Mars. These interactives were pilot tested at Arvada High School in Colorado.

Virtual Presence: One Step Beyond Reality

NASA Technical Reports Server (NTRS)

Budden, Nancy Ann

1997-01-01

Our primary objective was to team up a group consisting of scientists and engineers from two different NASA cultures, and simulate an interactive teleoperated robot conducting geologic field work on the Moon or Mars. The information derived from the experiment will benefit both the robotics team and the planetary exploration team in the areas of robot design and development, and mission planning and analysis. The Earth Sciences and Space and Life Sciences Division combines the past with the future contributing experience from Apollo crews exploring the lunar surface, knowledge of reduced gravity environments, the performance limits of EVA suits, and future goals for human exploration beyond low Earth orbit. The Automation, Robotics. and Simulation Division brings to the table the technical expertise of robotic systems, the future goals of highly interactive robotic capabilities, treading on the edge of technology by joining for the first time a unique combination of telepresence with virtual reality.

ARIES: Enabling Visual Exploration and Organization of Art Image Collections.

PubMed

Crissaff, Lhaylla; Wood Ruby, Louisa; Deutch, Samantha; DuBois, R Luke; Fekete, Jean-Daniel; Freire, Juliana; Silva, Claudio

2018-01-01

Art historians have traditionally used physical light boxes to prepare exhibits or curate collections. On a light box, they can place slides or printed images, move the images around at will, group them as desired, and visual-ly compare them. The transition to digital images has rendered this workflow obsolete. Now, art historians lack well-designed, unified interactive software tools that effectively support the operations they perform with physi-cal light boxes. To address this problem, we designed ARIES (ARt Image Exploration Space), an interactive image manipulation system that enables the exploration and organization of fine digital art. The system allows images to be compared in multiple ways, offering dynamic overlays analogous to a physical light box, and sup-porting advanced image comparisons and feature-matching functions, available through computational image processing. We demonstrate the effectiveness of our system to support art historians tasks through real use cases.

BIOLOGICAL NETWORK EXPLORATION WITH CYTOSCAPE 3

PubMed Central

Su, Gang; Morris, John H.; Demchak, Barry; Bader, Gary D.

2014-01-01

Cytoscape is one of the most popular open-source software tools for the visual exploration of biomedical networks composed of protein, gene and other types of interactions. It offers researchers a versatile and interactive visualization interface for exploring complex biological interconnections supported by diverse annotation and experimental data, thereby facilitating research tasks such as predicting gene function and pathway construction. Cytoscape provides core functionality to load, visualize, search, filter and save networks, and hundreds of Apps extend this functionality to address specific research needs. The latest generation of Cytoscape (version 3.0 and later) has substantial improvements in function, user interface and performance relative to previous versions. This protocol aims to jump-start new users with specific protocols for basic Cytoscape functions, such as installing Cytoscape and Cytoscape Apps, loading data, visualizing and navigating the network, visualizing network associated data (attributes) and identifying clusters. It also highlights new features that benefit experienced users. PMID:25199793

Interacting steps with finite-range interactions: Analytical approximation and numerical results

NASA Astrophysics Data System (ADS)

Jaramillo, Diego Felipe; Téllez, Gabriel; González, Diego Luis; Einstein, T. L.

2013-05-01

We calculate an analytical expression for the terrace-width distribution P(s) for an interacting step system with nearest- and next-nearest-neighbor interactions. Our model is derived by mapping the step system onto a statistically equivalent one-dimensional system of classical particles. The validity of the model is tested with several numerical simulations and experimental results. We explore the effect of the range of interactions q on the functional form of the terrace-width distribution and pair correlation functions. For physically plausible interactions, we find modest changes when next-nearest neighbor interactions are included and generally negligible changes when more distant interactions are allowed. We discuss methods for extracting from simulated experimental data the characteristic scale-setting terms in assumed potential forms.

The E-music box: an empirical method for exploring the universal capacity for musical production and for social interaction through music

PubMed Central

Novembre, Giacomo; Varlet, Manuel; Muawiyath, Shujau; Stevens, Catherine J.; Keller, Peter E.

2015-01-01

Humans are assumed to have a natural—universal—predisposition for making music and for musical interaction. Research in this domain is, however, typically conducted with musically trained individuals, and therefore confounded with expertise. Here, we present a rediscovered and updated invention—the E-music box—that we establish as an empirical method to investigate musical production and interaction in everyone. The E-music box transforms rotatory cyclical movements into pre-programmable digital musical output, with tempo varying according to rotation speed. The user’s movements are coded as continuous oscillatory data, which can be analysed using linear or nonlinear analytical tools. We conducted a proof-of-principle experiment to demonstrate that, using this method, pairs of non-musically trained individuals can interact according to conventional musical practices (leader/follower roles and lower-pitch dominance). The results suggest that the E-music box brings ‘active’ and ‘interactive’ musical capacities within everyone’s reach. We discuss the potential of this method for exploring the universal predisposition for music making and interaction in developmental and cross-cultural contexts, and for neurologic musical therapy and rehabilitation. PMID:26715993

Children's Responses to Mother-Infant and Father-Infant Interaction with a Baby Sibling: Jealousy or Joy?

PubMed Central

Volling, Brenda L.; Yu, Tianyi; Gonzalez, Richard; Kennedy, Denise E.; Rosenberg, Lauren; Oh, Wonjung

2014-01-01

Firstborn children's reactions to mother-infant and father-infant interaction after a sibling's birth were examined in an investigation of 224 families. Triadic observations of parent-infant-sibling interaction were conducted at 1 month after the birth. Parents reported on children's problem behaviors at 1 and 4 months after the birth, and completed the Attachment Q-sort before the birth. Latent Profile Analysis (LPA) identified four latent classes (behavioral profiles) for mother-infant and father-infant interaction: regulated-exploration, disruptive-dysregulated, approach-avoidant, and anxious-clingy. A fifth class, attention-seeking, was found with fathers. The regulated-exploration class was the normative pattern (60%), with few children in the disruptive class (2.7%). Approach-avoidant children had more behavior problems at 4 months than any other class with the exception of the disruptive children who were higher on aggression and attention problems. Before the birth, anxious-clingy children had less secure attachments to their fathers than approach avoidant children, but more secure attachments to their mothers. Results underscore individual differences in firstborns' behavioral responses to parent-infant interaction and the importance of a person-centered approach for understanding children's jealousy. PMID:25150371

Drug-drug interactions involving lysosomes: mechanisms and potential clinical implications.

PubMed

Logan, Randall; Funk, Ryan S; Axcell, Erick; Krise, Jeffrey P

2012-08-01

Many commercially available, weakly basic drugs have been shown to be lysosomotropic, meaning they are subject to extensive sequestration in lysosomes through an ion trapping-type mechanism. The extent of lysosomal trapping of a drug is an important therapeutic consideration because it can influence both activity and pharmacokinetic disposition. The administration of certain drugs can alter lysosomes such that their accumulation capacity for co-administered and/or secondarily administered drugs is altered. In this review the authors explore what is known regarding the mechanistic basis for drug-drug interactions involving lysosomes. Specifically, the authors address the influence of drugs on lysosomal pH, volume and lipid processing. Many drugs are known to extensively accumulate in lysosomes and significantly alter their structure and function; however, the therapeutic and toxicological implications of this remain controversial. The authors propose that drug-drug interactions involving lysosomes represent an important potential source of variability in drug activity and pharmacokinetics. Most evaluations of drug-drug interactions involving lysosomes have been performed in cultured cells and isolated tissues. More comprehensive in vivo evaluations are needed to fully explore the impact of this drug-drug interaction pathway on therapeutic outcomes.

Exploring the affective dimension of the life review process: Facilitators' interactional strategies for fostering personhood and social value among older adults with early dementia.

PubMed

Williams, Beverly R; Blizard, Tracie I; Goode, Patricia S; Harada, Caroline N; Woodby, Lesa L; Burgio, Kathryn L; Sims, Richard V

2014-07-01

We employed an auto-ethnography approach to explore the affective dimension of life review sessions with community-dwelling older military veterans with minor cognitive impairment (MCI) and early dementia. Using researchers' analytic memos, we identified facilitators' interactional strategies that fostered the participant's sense of personal identity, dignity and social self-worth. Interaction among participant, caregiver, and facilitators evoked a range of emotional responses, offering a window into the affective world of MCI and early dementia. Positive emotional responses outnumbered negative emotional responses by a ratio of two-to-one in the life review sessions; however, negative emotions were more revelatory of current struggles with declines in health and function. Facilitators utilized two interactional strategies, in particular, to foster personhood and social value of participants: focusing on the participant and creating an empathic connection with the participant. Further work is needed to understand the role of emotions in research interactions and to examine the psychosocial mechanisms through which positive affect functions in promoting identity, personhood and social value among persons with MCI and early dementia. © The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.