Emergency medicine resident crisis resource management ability: a simulation-based longitudinal study

PubMed Central

Clarke, Samuel; Horeczko, Timothy; Carlisle, Matthew; Barton, Joseph D.; Ng, Vivienne; Al-Somali, Sameerah; Bair, Aaron E.

2014-01-01

Background Simulation has been identified as a means of assessing resident physicians’ mastery of technical skills, but there is a lack of evidence for its utility in longitudinal assessments of residents’ non-technical clinical abilities. We evaluated the growth of crisis resource management (CRM) skills in the simulation setting using a validated tool, the Ottawa Crisis Resource Management Global Rating Scale (Ottawa GRS). We hypothesized that the Ottawa GRS would reflect progressive growth of CRM ability throughout residency. Methods Forty-five emergency medicine residents were tracked with annual simulation assessments between 2006 and 2011. We used mixed-methods repeated-measures regression analyses to evaluate elements of the Ottawa GRS by level of training to predict performance growth throughout a 3-year residency. Results Ottawa GRS scores increased over time, and the domains of leadership, problem solving, and resource utilization, in particular, were predictive of overall performance. There was a significant gain in all Ottawa GRS components between postgraduate years 1 and 2, but no significant difference in GRS performance between years 2 and 3. Conclusions In summary, CRM skills are progressive abilities, and simulation is a useful modality for tracking their development. Modification of this tool may be needed to assess advanced learners’ gains in performance. PMID:25499769

Advancing Stage 2 Research on Measures for Monitoring Kindergarten Reading Progress.

PubMed

Clemens, Nathan H; Soohoo, Michelle M; Wiley, Colby P; Hsiao, Yu-Yu; Estrella, Ivonne; Allee-Smith, Paula J; Yoon, Myeongsun

Although several measures exist for frequently monitoring early reading progress, little research has specifically investigated their technical properties when administered on a frequent basis with kindergarten students. In this study, kindergarten students ( N = 137) of whom the majority was receiving supplemental intervention for reading skills were monitored using Letter Sound Fluency, Phoneme Segmentation Fluency, Word Reading Fluency, Nonsense Word Fluency, Highly Decodable Passages, and Spelling on a biweekly basis between February and May. Acceptable reliability was observed for all measures. Analyses of slope validity using latent growth models, latent change score models, and slope differences according to level of year-end achievement indicated that the relation of slope to overall reading skills varied across the measures. A suggested approach to kindergarten students' reading progress is offered that includes Letter Sound Fluency and a measure of word-reading skills to provide a comprehensive picture of student growth toward important year-end reading outcomes.

Building Professional and Technical Skills in the Use of Earth Observations through the NASA DEVELOP National Program: Best Practices & Lessons Learned

NASA Astrophysics Data System (ADS)

Crepps, G.; Ross, K. W.; Childs-Gleason, L. M.; Allsbrook, K. N.; Rogers, L.; Ruiz, M. L.; Clayton, A.

2017-12-01

The NASA DEVELOP National Program offers 10-week research opportunities to participants to work on rapid feasibility projects utilizing NASA Earth observations in a variety of applications, including ecological forecasting, water resources, disasters, and health and air quality. DEVELOP offers a unique collaborative environment in which students, recent graduates, and transitioning career professionals are placed on interdisciplinary teams to conduct projects. DEVELOP offers a variety of opportunities and resources to build participants technical skills in remote sensing and GIS, as well as interpersonal and leadership skills. As a capacity building program, DEVELOP assesses participants' growth by using entrance and exit personal growth assessments, as well as gathering general program feedback through an exit survey. All of this information is fed back into the program for continual improvement. DEVELOP also offers a progression of opportunities through which participants can advance through the program, allowing participants to build a diverse set of technical and leadership skills. This presentation will explore best practices including the use of pre- and post-growth assessments, offering advanced leadership opportunities, and overall capacity building impacts on participants.

Data Stewardship: Managing Personally Identifiable Information in Electronic Student Education Records. SLDS Technical Brief 2. NCES 2011-602

ERIC Educational Resources Information Center

National Center for Education Statistics, 2010

2010-01-01

The growth of electronic student data in America's education system has focused attention on the ways these data are collected, processed, stored, and used. The use of records in Statewide Longitudinal Data Systems to follow the progress of individual students over time requires maintaining student education records that include information that…

Silicon on ceramic process. Silicon sheet growth development for the large-area silicon sheet task of the low-cost silicon solar array project

NASA Technical Reports Server (NTRS)

Zook, J. D.; Heaps, J. D.; Maciolek, R. B.; Koepke, B. G.; Butter, C. D.; Schuldt, S. B.

1977-01-01

The technical and economic feasibility of producing solar-cell-quality sheet silicon was investigated. The sheets were made by coating one surface of carbonized ceramic substrates with a thin layer of large-grain polycrystalline silicon from the melt. Significant progress was made in all areas of the program.

Progress Monitoring Instrument Development: Silent Reading Fluency, Vocabulary, and Reading Comprehension. Technical Report #1110

ERIC Educational Resources Information Center

Nese, Joseph F. T.; Anderson, Daniel; Hoelscher, Kyle; Tindal, Gerald; Alonzo, Julie

2011-01-01

Curriculum-based measurement (CBM) is designed to measure students' academic status and growth so the effectiveness of instruction may be evaluated. In the most popular forms of reading CBM, the student's oral reading fluency is assessed. This behavior is difficult to sample in a computer-based format, a limitation that may be a function of the…

Achondroplasia and multiple-suture craniosynostosis.

PubMed

Albino, Frank P; Wood, Benjamin C; Oluigbo, Chima O; Lee, Angela C; Oh, Albert K; Rogers, Gary F

2015-01-01

Genetic mutations in the fibroblast growth factor receptor 3 gene may lead to achondroplasia or syndromic forms of craniosynostosis. Despite sharing a common genetic basis, craniosynostosis has rarely been described in cases of confirmed achondroplasia. We report an infant with achondroplasia who developed progressive multiple-suture craniosynostosis to discuss the genetic link between these clinical entities and to describe the technical challenges associated with the operative management.

South China Sea disputes: ASEAN’s Role in Addressing Disputes with China

DTIC Science & Technology

2013-12-13

Philippines, Singapore, and Thailand. The main aims of the organization were to strengthen cooperation in the economic , social, cultural , technical...community is comprised of three pillars, namely the ASEAN Political-Security Community, ASEAN Economic Community and ASEAN Socio- Cultural Community...Declaration, ASEAN would focus on accelerating the economic growth, social progress and cultural development in the region, and promoting regional peace

Direct observation of crystal growth from solution using optical investigation of a growing crystal face

NASA Technical Reports Server (NTRS)

Lal, Ravindra

1994-01-01

The first technical report for the period 1 Jan. 1993 till 31 Dec. 1993 for the research entitled, 'Direct observation of crystal growth from solution using Optical Investigation of a growing crystal Face' is presented. The work on the project did not start till 1 June 1993 due to the non-availability of the required personnel. The progress of the work during the period 1 June 1993 till the end of 1993 is described. Significant progress was made for testing various optical diagnostic techniques for monitoring crystal solution. Some of the techniques that are being tested are: heterodyne detection technique, in which changes in phase are measured as a interferometric function of time/crystal growth; a conventional technique, in which a fringe brightness is measured as a function of crystal growth/time; and a Mach-Zehnder interferometric technique in which a fringe brightness is measured as a function of time to obtain information on concentration changes. During the second year it will be decided to incorporate the best interferometric technique along with the ellipsometric technique, to obtain real time in-situ growth rate measurements. A laboratory mock-up of the first two techniques were made and tested.

Proceedings of the 26th Project Integration Meeting

NASA Technical Reports Server (NTRS)

1986-01-01

Progress made by the Flat-plate Solar Array (FSA) Project is described for the period July 1985 to April 1986. Included are reports on silicon sheet growth and characterization, silicon material, process development, high-efficienty cells, environmental isolation, engineering sciences, and reliability physics. Also included are technical and plenary presentations made at the 26th Project Integration Meeting (PIM) held on April 29 to 30 and May 1, 1986.

The Role of Soviet Trade Unions in the Lifelong Education of Workers. Adult Education in Europe. Studies and Documents No. 17.

ERIC Educational Resources Information Center

Yazykova, V. S.

In the U.S.S.R., the trade unions see the continuous growth of the general educational, cultural and technical level of all workers as one of the conditions of social and scientific progress in the interests of the working class. The role of the unions in the lifelong education of the population is determined by their status in the political…

48 CFR 742.1170-4 - Progress reporting requirements and contract clause.

Code of Federal Regulations, 2010 CFR

2010-10-01

... progress. (b) Because the cognizant technical officer is the individual most familiar with the contractor's performance, the contractor must submit the progress reports directly to the cognizant technical officer. The cognizant technical officer must review the reports and advise the contracting officer, in writing, of any...

Area Reports. Advanced materials and devices research area. Silicon materials research task, and advanced silicon sheet task

NASA Technical Reports Server (NTRS)

1986-01-01

The objectives of the Silicon Materials Task and the Advanced Silicon Sheet Task are to identify the critical technical barriers to low-cost silicon purification and sheet growth that must be overcome to produce a PV cell substrate material at a price consistent with Flat-plate Solar Array (FSA) Project objectives and to overcome these barriers by performing and supporting appropriate R&D. Progress reports are given on silicon refinement using silane, a chemical vapor transport process for purifying metallurgical grade silicon, silicon particle growth research, and modeling of silane pyrolysis in fluidized-bed reactors.

Analysis of World Economic Variables Using Multidimensional Scaling

PubMed Central

Machado, J.A. Tenreiro; Mata, Maria Eugénia

2015-01-01

Waves of globalization reflect the historical technical progress and modern economic growth. The dynamics of this process are here approached using the multidimensional scaling (MDS) methodology to analyze the evolution of GDP per capita, international trade openness, life expectancy, and education tertiary enrollment in 14 countries. MDS provides the appropriate theoretical concepts and the exact mathematical tools to describe the joint evolution of these indicators of economic growth, globalization, welfare and human development of the world economy from 1977 up to 2012. The polarization dance of countries enlightens the convergence paths, potential warfare and present-day rivalries in the global geopolitical scene. PMID:25811177

Chemical Fixation of CO2 in Coal Combustion Products and Recycling through Biosystems

DOE Office of Scientific and Technical Information (OSTI.GOV)

C. Henry Copeland; Paul Pier; Samantha Whitehead

2001-09-30

This Annual Technical Progress Report presents the principle results in enhanced growth of algae using coal combustion products as a catalyst to increase bicarbonate levels in solution. A co-current reactor is present that increases the gas phase to bicarbonate transfer rate by a factor of five to nine. The bicarbonate concentration at a given pH is approximately double that obtained using a control column of similar construction. Algae growth experiments were performed under laboratory conditions to obtain baseline production rates and to perfect experimental methods. The final product of this initial phase in algae production is presented.

Silicon-on Ceramic Process: Silicon Sheet Growth and Device Development for the Large-area Silicon Sheet and Cell Development Tasks of the Low-cost Solar Array Project

NASA Technical Reports Server (NTRS)

Chapman, P. W.; Zook, J. D.; Heaps, J. D.; Grung, B. L.; Koepke, B.; Schuldt, S. B.

1979-01-01

The technical and economic feasibility of producing solar cell-quality silicon was investigated. This was done by coating one surface of carbonized ceramic substrates with a thin layer of large-grain polycrystalline silicon from the melt. Significant progress in the following areas was demonstrated: (1) fabricating a 10 sq cm cell having 9.9 percent conversion efficiency; (2) producing a 225 sq cm layer of sheet silicon; and (3) obtaining 100 microns thick coatings at pull speed of 0.15 cm/sec, although approximately 50 percent of the layer exhibited dendritic growth.

Genetic correction using engineered nucleases for gene therapy applications.

PubMed

Li, Hongmei Lisa; Nakano, Takao; Hotta, Akitsu

2014-01-01

Genetic mutations in humans are associated with congenital disorders and phenotypic traits. Gene therapy holds the promise to cure such genetic disorders, although it has suffered from several technical limitations for decades. Recent progress in gene editing technology using tailor-made nucleases, such as meganucleases (MNs), zinc finger nucleases (ZFNs), TAL effector nucleases (TALENs) and, more recently, CRISPR/Cas9, has significantly broadened our ability to precisely modify target sites in the human genome. In this review, we summarize recent progress in gene correction approaches of the human genome, with a particular emphasis on the clinical applications of gene therapy. © 2013 The Authors Development, Growth & Differentiation © 2013 Japanese Society of Developmental Biologists.

Webinar May 17: Fuel Cell Electric Bus Progress Toward Meeting Technical

Science.gov Websites

Targets | News | NREL Webinar May 17: Fuel Cell Electric Bus Progress toward Meeting Technical Targets Webinar May 17: Fuel Cell Electric Bus Progress toward Meeting Technical Targets May 14, 2018 The U.S. Department of Energy's (DOE's) Fuel Cell Technologies Office will present a live webinar titled

US productivity slowdown: a case of statistical myopia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Darby, M.R.

1984-06-01

The author argues that the productivity panic is based upon statistical myopia, and that a careful analysis within the perspective of the entire 20th century discloses no substantial variation in what is described as growth in total factor productivity or technical progress. He finds no substantial variations in trend growth rates of private labor productivity since 1900 if reasonable adjustments are made for the effects of demographic trends on the average quality of labor. Even if one were to ignore the effects of demographic shifts, the measured growth rates of productivity, total private hours, and private employment have essentially themore » same values in 1956-79 as for 1900-29. Some of the primary data base for the paper appears in the appendix. 39 references, 3 figures, 9 tables.« less

25 CFR 30.111 - When should the tribal governing body or school board request technical assistance?

Code of Federal Regulations, 2011 CFR

2011-04-01

... request technical assistance? 30.111 Section 30.111 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION ADEQUATE YEARLY PROGRESS Defining Adequate Yearly Progress Technical Assistance § 30.111 When should the tribal governing body or school board request technical assistance? In order to...

Voluntary medical male circumcision scale-up in Nyanza, Kenya: evaluating technical efficiency and productivity of service delivery.

PubMed

Omondi Aduda, Dickens S; Ouma, Collins; Onyango, Rosebella; Onyango, Mathews; Bertrand, Jane

2015-01-01

Voluntary medical male circumcision (VMMC) service delivery is complex and resource-intensive. In Kenya's context there is still paucity of information on resource use vis-à-vis outputs as programs scale up. Knowledge of technical efficiency, productivity and potential sources of constraints is desirable to improve decision-making. To evaluate technical efficiency and productivity of VMMC service delivery in Nyanza in 2011/2012 using data envelopment analysis. Comparative process evaluation of facilities providing VMMC in Nyanza in 2011/2012 using output orientated data envelopment analysis. Twenty one facilities were evaluated. Only 1 of 7 variables considered (total elapsed operation time) significantly improved from 32.8 minutes (SD 8.8) in 2011 to 30 minutes (SD 6.6) in 2012 (95%CI = 0.0350-5.2488; p = 0.047). Mean scale technical efficiency significantly improved from 91% (SD 19.8) in 2011 to 99% (SD 4.0) in 2012 particularly among outreach compared to fixed service delivery facilities (CI -31.47959-4.698508; p = 0.005). Increase in mean VRS technical efficiency from 84% (SD 25.3) in 2011 and 89% (SD 25.1) in 2012 was not statistically significant. Benchmark facilities were #119 and #125 in 2011 and #103 in 2012. Malmquist Productivity Index (MPI) at fixed facilities declined by 2.5% but gained by 4.9% at outreach ones by 2012. Total factor productivity improved by 83% (p = 0.032) in 2012, largely due to progress in technological efficiency by 79% (p = 0.008). Significant improvement in scale technical efficiency among outreach facilities in 2012 was attributable to accelerated activities. However, ongoing pure technical inefficiency requires concerted attention. Technological progress was the key driver of service productivity growth in Nyanza. Incorporating service-quality dimensions and using stepwise-multiple criteria in performance evaluation enhances comprehensiveness and validity. These findings highlight site-level resource use and sources of variations in VMMC service productivity, which are important for program planning.

25 CFR 30.110 - What is the process for requesting technical assistance to develop an alternative definition of AYP?

Code of Federal Regulations, 2011 CFR

2011-04-01

..., DEPARTMENT OF THE INTERIOR EDUCATION ADEQUATE YEARLY PROGRESS Defining Adequate Yearly Progress Technical Assistance § 30.110 What is the process for requesting technical assistance to develop an alternative... 25 Indians 1 2011-04-01 2011-04-01 false What is the process for requesting technical assistance...

25 CFR 30.110 - What is the process for requesting technical assistance to develop an alternative definition of AYP?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What is the process for requesting technical assistance..., DEPARTMENT OF THE INTERIOR EDUCATION ADEQUATE YEARLY PROGRESS Defining Adequate Yearly Progress Technical Assistance § 30.110 What is the process for requesting technical assistance to develop an alternative...

Surgical resident technical skill self-evaluation: increased precision with training progression.

PubMed

Quick, Jacob A; Kudav, Vishal; Doty, Jennifer; Crane, Megan; Bukoski, Alex D; Bennett, Bethany J; Barnes, Stephen L

2017-10-01

Surgical resident ability to accurately evaluate one's own skill level is an important part of educational growth. We aimed to determine if differences exist between self and observer technical skill evaluation of surgical residents performing a single procedure. We prospectively enrolled 14 categorical general surgery residents (six post-graduate year [PGY] 1-2, three PGY 3, and five PGY 4-5). Over a 6-month period, following each laparoscopic cholecystectomy, residents and seven faculty each completed the Objective Structured Assessment of Technical Skills (OSATS). Spearman's coefficient was calculated for three groups: senior (PGY 4-5), PGY3, and junior (PGY 1-2). Rho (ρ) values greater than 0.8 were considered well correlated. Of the 125 paired assessments (resident-faculty each evaluating the same case), 58 were completed for senior residents, 54 for PGY3 residents, and 13 for junior residents. Using the mean from all OSATS categories, trainee self-evaluations correlated well to faculty (senior ρ 0.97, PGY3 ρ 0.9, junior ρ 0.9). When specific OSATS categories were analyzed, junior residents exhibited poor correlation in categories of respect for tissue (ρ -0.5), instrument handling (ρ 0.71), operative flow (ρ 0.41), use of assistants (ρ 0.05), procedural knowledge (ρ 0.32), and overall comfort with the procedure (ρ 0.73). PGY3 residents lacked correlation in two OSATS categories, operative flow (ρ 0.7) and procedural knowledge (ρ 0.2). Senior resident self-evaluations exhibited strong correlations to observers in all areas. Surgical residents improve technical skill self-awareness with progressive training. Less-experienced trainees have a tendency to over-or-underestimate technical skill. Copyright © 2017 Elsevier Inc. All rights reserved.

14 CFR 1274.701 - Suspension or termination.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Agreement if the recipient is not making anticipated technical progress, if the recipient materially changes...) Similarly, the recipient may terminate the agreement if, for example, technical progress is not being made, if the commercial recipient shifts its technical emphasis, or if other technological advances have...

14 CFR 1274.701 - Suspension or termination.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Agreement if the recipient is not making anticipated technical progress, if the recipient materially changes...) Similarly, the recipient may terminate the agreement if, for example, technical progress is not being made, if the commercial recipient shifts its technical emphasis, or if other technological advances have...

Flat-plate solar array progress and plans

NASA Technical Reports Server (NTRS)

Callaghan, W. T.; Henry, P. K.

1984-01-01

The Flat-Plate Solar Array Project (FSA), sponsored by the U.S. Department of Energy (DOE) and managed by the Jet Propulsion Laboratory (JPL), has achieved progress in a broad range of technical activities since that reported at the Fourth European Communities Conference. A particularly important analysis has been completed recently which confirms the adoption into practice by the U.S. Photovoltaic (PV Industry, of all the low-cost module technology elements proposed at the 16th Project Integration Meeting for a $2.80/Wp (1980 U.S. Dollars) design approach in the fall of 1980. This work presents along with a projection, using the same techniques, for what is believed to be a very credible ribbon-based module design for less that $0.55/Wp (1980 U.S. Dollars). Other areas to be reported upon include low-cost Si feedstock refinement; ribbon growth; process sequence development for cells; environmental isolation; engineering science investigations; and module testing progress.

Progress in Scientific and Technical Communications, 1968 Annual Report.

ERIC Educational Resources Information Center

Federal Council for Science and Technology, Washington, DC. Committee on Scientific and Technical Information.

This sixth annual report describes progress achieved by the Federal Government in improving the communication of scientific and technical information to support and enhance national science and technology. Included in the report are details regarding the scientific and technical activities of individual Federal Agencies, such as the Atomic Energy…

Emerging Trends in the Globalization of Knowledge: The Role of the Technical Report in Aerospace Research and Development

NASA Technical Reports Server (NTRS)

Pinelli, Thomas E.; Golich, Vicki L.

1997-01-01

Economists, management theorists, business strategists, and governments alike recognize knowledge as the single most important resource in today's global economy. Because of its relationship to technological progress and economic growth, many governments have taken a keen interest in knowledge, specifically its production, transfer, and use. This paper focuses on the technical report as a product for disseminating the results of aerospace research and development (R&D) and its use and importance to aerospace engineers and scientists. The emergence of knowledge as an intellectual asset, its relationship to innovation, and its importance in a global economy provides the context for the paper. The relationships between government and knowledge and between government and innovation are used to placed knowledge within the context of publicly-funded R&D. Data, including the reader preferences of NASA technical reports, are derived from the NASA/DOD Aerospace Knowledge Diffusion Research Project, a ten-year study of knowledge diffusion in the U.S. aerospace industry.

48 CFR 2452.242-71 - Contract management system.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., concise summary of technical progress made and the costs incurred for each task during the reporting... technical progress made for each task during the reporting period; and (B) Identifies problems, or potential... and progress reporting as described herein. (b) The contract management system shall consist of two...

ANNUAL REPORT, JULY 1, 1957

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1958-10-31

The progress and trends of research are presented along with a description of operational, service, end administrative activities. Some scientific and technical details are given on research programs in the physical sciences, life sciences, and engineering, however, more complete technical information is available in quarterly progress reports, BNL technical reports, and scientific and technical periodicals. A bibliography of these publications is appended. (For preceding period see BNL-426.) (D.E.B.)

20 CFR 411.180 - What is timely progress toward self-supporting employment?

Code of Federal Regulations, 2010 CFR

2010-04-01

... certificate or vocational or technical training that will enhance your ability to return to work. In addition...-secondary education requirement or vocational or technical training requirement in the applicable progress... this 12-month period; or (iv) You must have been enrolled in a vocational or technical training program...

Proceedings of the 2000 U.S. DOE Hydrogen Program Review

DOE Office of Scientific and Technical Information (OSTI.GOV)

NREL

2000-11-01

The 2000 US Department of Energy (DOE) Hydrogen Program Review was sponsored by the Office of Power Delivery Systems, Office of Power Technologies, US Department of Energy. The proceedings from this meeting serve as an important technology reference for the DOE Hydrogen Program. This document contains technical progress reports on research and technology validation projects funded by the DOE Hydrogen Program in Fiscal Year 2000. The growth of fuel cell technology will provide a basis for the establishment of the hydrogen option into both transportation and electricity supply markets.

High CD49f expression is associated with osteosarcoma tumor progression: a study using patient-derived primary cell cultures.

PubMed

Penfornis, Patrice; Cai, David Z; Harris, Michael R; Walker, Ryan; Licini, David; Fernandes, Joseph D A; Orr, Griffin; Koganti, Tejaswi; Hicks, Chindo; Induru, Spandana; Meyer, Mark S; Khokha, Rama; Barr, Jennifer; Pochampally, Radhika R

2014-08-01

Overall prognosis for osteosarcoma (OS) is poor despite aggressive treatment options. Limited access to primary tumors, technical challenges in processing OS tissues, and the lack of well-characterized primary cell cultures has hindered our ability to fully understand the properties of OS tumor initiation and progression. In this study, we have isolated and characterized cell cultures derived from four central high-grade human OS samples. Furthermore, we used the cell cultures to study the role of CD49f in OS progression. Recent studies have implicated CD49f in stemness and multipotency of both cancer stem cells and mesenchymal stem cells. Therefore, we investigated the role of CD49f in osteosarcomagenesis. First, single cell suspensions of tumor biopsies were subcultured and characterized for cell surface marker expression. Next, we characterized the growth and differentiation properties, sensitivity to chemotherapy drugs, and anchorage-independent growth. Xenograft assays showed that cell populations expressing CD49f(hi) /CD90(lo) cell phenotype produced an aggressive tumor. Multiple lines of evidence demonstrated that inhibiting CD49f decreased the tumor-forming ability. Furthermore, the CD49f(hi) /CD90(lo) cell population is generating more aggressive OS tumor growth and indicating this cell surface marker could be a potential candidate for the isolation of an aggressive cell type in OSs. © 2014 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

Report of the Panel on Computer and Information Technology

NASA Technical Reports Server (NTRS)

Lundstrom, Stephen F.; Larsen, Ronald L.

1984-01-01

Aircraft have become more and more dependent on computers (information processing) for improved performance and safety. It is clear that this activity will grow, since information processing technology has advanced by a factor of 10 every 5 years for the past 35 years and will continue to do so. Breakthroughs in device technology, from vacuum tubes through transistors to integrated circuits, contribute to this rapid pace. This progress is nearly matched by similar, though not as dramatic, advances in numerical software and algorithms. Progress has not been easy. Many technical and nontechnical challenges were surmounted. The outlook is for continued growth in capability but will require surmounting new challenges. The technology forecast presented in this report has been developed by extrapolating current trends and assessing the possibilities of several high-risk research topics. In the process, critical problem areas that require research and development emphasis have been identified. The outlook assumes a positive perspective; the projected capabilities are possible by the year 2000, and adequate resources will be made available to achieve them. Computer and information technology forecasts and the potential impacts of this technology on aeronautics are identified. Critical issues and technical challenges underlying the achievement of forecasted performance and benefits are addressed.

Voluntary Medical Male Circumcision Scale-Up in Nyanza, Kenya: Evaluating Technical Efficiency and Productivity of Service Delivery

PubMed Central

Omondi Aduda, Dickens S.; Ouma, Collins; Onyango, Rosebella; Onyango, Mathews; Bertrand, Jane

2015-01-01

Background Voluntary medical male circumcision (VMMC) service delivery is complex and resource-intensive. In Kenya’s context there is still paucity of information on resource use vis-à-vis outputs as programs scale up. Knowledge of technical efficiency, productivity and potential sources of constraints is desirable to improve decision-making. Objective To evaluate technical efficiency and productivity of VMMC service delivery in Nyanza in 2011/2012 using data envelopment analysis. Design Comparative process evaluation of facilities providing VMMC in Nyanza in 2011/2012 using output orientated data envelopment analysis. Results Twenty one facilities were evaluated. Only 1 of 7 variables considered (total elapsed operation time) significantly improved from 32.8 minutes (SD 8.8) in 2011 to 30 minutes (SD 6.6) in 2012 (95%CI = 0.0350–5.2488; p = 0.047). Mean scale technical efficiency significantly improved from 91% (SD 19.8) in 2011 to 99% (SD 4.0) in 2012 particularly among outreach compared to fixed service delivery facilities (CI -31.47959–4.698508; p = 0.005). Increase in mean VRS technical efficiency from 84% (SD 25.3) in 2011 and 89% (SD 25.1) in 2012 was not statistically significant. Benchmark facilities were #119 and #125 in 2011 and #103 in 2012. Malmquist Productivity Index (MPI) at fixed facilities declined by 2.5% but gained by 4.9% at outreach ones by 2012. Total factor productivity improved by 83% (p = 0.032) in 2012, largely due to progress in technological efficiency by 79% (p = 0.008). Conclusions Significant improvement in scale technical efficiency among outreach facilities in 2012 was attributable to accelerated activities. However, ongoing pure technical inefficiency requires concerted attention. Technological progress was the key driver of service productivity growth in Nyanza. Incorporating service-quality dimensions and using stepwise-multiple criteria in performance evaluation enhances comprehensiveness and validity. These findings highlight site-level resource use and sources of variations in VMMC service productivity, which are important for program planning. PMID:25706119

Evaporation by mechanical vapor recompression. Technical progress report, September 1-December 31, 1979

DOE Office of Scientific and Technical Information (OSTI.GOV)

Iverson, C.H.; Coury, G.E.

1979-01-01

Progress to date in the development of a study of the application of the technologies of mechanical vapor recompression and falling film evaporators as applied to the beet sugar industry is reported. Progress is reported in the following areas: technical literature search and plant visitations of existing applications of VR/FFE.

25 CFR 30.109 - Will the Secretary provide assistance in developing an alternative AYP definition?

Code of Federal Regulations, 2011 CFR

2011-04-01

... EDUCATION ADEQUATE YEARLY PROGRESS Defining Adequate Yearly Progress Technical Assistance § 30.109 Will the... Bureau, shall provide technical assistance either directly or through contract to the tribal governing...

25 CFR 30.109 - Will the Secretary provide assistance in developing an alternative AYP definition?

Code of Federal Regulations, 2010 CFR

2010-04-01

... EDUCATION ADEQUATE YEARLY PROGRESS Defining Adequate Yearly Progress Technical Assistance § 30.109 Will the... Bureau, shall provide technical assistance either directly or through contract to the tribal governing...

Monitoring the Durability Performance of Concrete in Nuclear Waste Containment. Technical Progress Report No. 3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ulm, Franz-Josef

2000-03-31

OAK-B135 Monitoring the Durability Performance of Concrete in Nuclear Waste Containment. Technical Progress Report No. 3(NOTE: Part II A item 1 indicates ''PAPER'', but a report is attached electronically)

Crosscutting Technology Development at the Center for Advanced Separation Technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Christopher E. Hull

2006-09-30

This Technical Progress Report describes progress made on the twenty nine subprojects awarded in the second year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Christopher E. Hull

2006-05-15

This Technical Progress Report describes progress made on the twenty nine subprojects awarded in the second year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

The Development and Technical Adequacy of Seventh-Grade Reading Comprehension Measures in a Progress Monitoring Assessment System. Technical Report #1102

ERIC Educational Resources Information Center

Park, Bitnara Jasmine; Alonzo, Julie; Tindal, Gerald

2011-01-01

This technical report describes the process of development and piloting of reading comprehension measures that are appropriate for seventh-grade students as part of an online progress screening and monitoring assessment system, http://easycbm.com. Each measure consists of an original fictional story of approximately 1,600 to 1,900 words with 20…

Generation and focusing of pulsed intense ion beams. Technical progress report, 1 October 1982 - 30 September, 1983

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hammer, D.A.; Kusse, B.R.; Sudan, R.N.

1983-07-01

The progress on this contract is described in three parts. The first deals with the technical operation of the LION accelerator. The second and third parts are concerned with the experimental results.

NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 66: Emerging Trends in the Globalization of Knowledge: The Role of the Technical Report in Aerospace Research and Development

NASA Technical Reports Server (NTRS)

Pinelli,Thomas E.; Golich, Vicki L.

1997-01-01

Economists, management theorists, business strategists, and governments alike recognize knowledge as the single most important resource in today's global economy. Because of its relationship to technological progress and economic growth, many governments have taken a keen interest in knowledge; specifically its production, transfer, and use. This paper focuses on the technical report as a product for disseminating the results of aerospace research and development (R&D) and its use and importance to aerospace engineers and scientists. The emergence of knowledge as an intellectual asset, its relationship to innovation, and its importance in a global economy provides the context for the paper. The relationships between government and knowledge and government and innovation are used to place knowledge within the context of publicly-funded R&D. Data, including the reader preferences of NASA technical reports, are derived from the NASA/DoD Aerospace Knowledge Diffusion Research Project, a ten-year study of knowledge diffusion in the U.S. aerospace industry.

Technical features of curriculum-based measures for beginning writers.

PubMed

McMaster, Kristen L; Xiaoqing Du; Pétursdóttir, Anna-Lind

2009-01-01

The purpose of the two studies reported in this article was to examine technical features of curriculum-based measures for beginning writers. In Study 1, 50 first graders responded to word copying, sentence copying, and story prompts. In Study 2, 50 additional first graders responded to letter, picture-word, picture-theme, and photo prompts. In both studies, 3- to 5-minute prompts were administered in winter and spring and scored using a variety of quantitative procedures. Students were also administered the Test of Written Language-Third Edition , and teacher ratings and scores on a district rubric for writing were collected. Test-retest (Study 1 only) and alternate-form reliability, criterion validity, and winter-to-spring growth were examined for each measure. Sentence-copying, story, picture-word, and photo prompts emerged as promising beginning-writing measures. Findings have implications for monitoring student progress within a seamless and flexible system across ages and skill levels.

X-33 Phase 2

NASA Technical Reports Server (NTRS)

1997-01-01

In response to Clause 17 of the Cooperative Agreement NCC8-115, Lockheed Martin Skunk Works has compiled an Annual Performance Report of the X-33/RLV Program. This report consists of individual reports from all industry team members, as well as NASA team centers. Contract award was announced on July 2, 1996 and the first milestone was hand delivered to NASA MSFC on July 17, 1996. The first year has been one of growth and progress as all team members staffed up and embarked on the technical adventure of the 20th century... the ultimate goal . . a Single Stage to Orbit (SSTO) Reuseable Launch Vehicle (RLV).

Engineering education in Bangladesh - an indicator of economic development

NASA Astrophysics Data System (ADS)

Chowdhury, Harun; Alam, Firoz

2012-05-01

Developing nations including Bangladesh are significantly lagging behind the millennium development target due to the lack of science, technology and engineering education. Bangladesh as a least developing country has only 44 engineers per million people. Its technological education and gross domestic product growth are not collinear. Although limited progress was made in humanities, basic sciences, agriculture and medical sciences, a vast gap is left in technical and engineering education. This paper describes the present condition of engineering education in the country and explores ways to improve engineering education in order to meet the national as well as global skills demand.

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Kindergarten. Technical Report # 0921

ERIC Educational Resources Information Center

Alonzo, Julie; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in kindergarten. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2008 and administered to approximately 2800 students from…

Agriculture and natural resources in a changing world - the role of irrigation

NASA Astrophysics Data System (ADS)

Sauer, T.; Havlík, P.; Schneider, U. A.; Kindermann, G.; Obersteiner, M.

2009-04-01

Fertile land and fresh water constitute two of the most fundamental resources for food production. These resources are affected by environmental, political, economic, and technical developments. Regional impacts may transmit to the world through increased trade. With a global forest and agricultural sector model, we quantify the impacts of increased demand for food due to population growth and economic development on potential land and water use. In particular, we investigate producer adaptation regarding crop and irrigation choice, agricultural market adjustments, and changes in the values of land and water. Against the background of resource sustainability and food security topics, this study integrates the spatial and operational heterogeneity of irrigation management into a global land use model. It represents a first large scale assessment of agricultural water use under explicit consideration of alternative irrigation options in their particular biophysical, economic, and technical context, accounting for international trade, motivation-based farming, and quantified aggregated impacts on land scarcity, water scarcity, and food supply. The inclusion of technical and economic aspects of irrigation choice into an integrated land use modeling framework provides new insights into the interdisciplinary trade-offs between determinants of global land use change. Agricultural responses to population and economic growth include considerable increases in irrigated area and agricultural water use, but reductions in the average water intensity. Different irrigation systems are preferred under different exogenous biophysical and socioeconomic conditions. Negligence of these adaptations would bias the burden of development on land and water scarcity. Without technical progress in agriculture, predicted population and income levels for 2030 would require substantial price adjustments for land, water, and food to equilibrate supply and demand.

Assessment Program Technical Progress Report, 1996-1997.

ERIC Educational Resources Information Center

McCown, Laurie; Fanning, Erin; Eickmeyer, Barbara

Coconino Community College (CCC) annually assesses its institutional effectiveness to demonstrate its commitment to improving programs and services to students. The 1996-97 Assessment Program Technical Progress Report records the assessment and institutional activities enacted during the academic year, detailing the assessment model, timelines,…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 1. Technical Report # 0919

ERIC Educational Resources Information Center

Alonzo, Julie; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grade 1. These measures, available as part of easyCBM [TM], an online progress monitoring assessment system, were developed in 2008 and administered to approximately 2800 students from schools…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 3. Technical Report # 09-02

ERIC Educational Resources Information Center

Alonzo, Julie; Lai, Cheng Fei; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 2. Technical Report # 0920

ERIC Educational Resources Information Center

Alonzo, Julie; Lai, Cheng Fei; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 5. Technical Report # 09-01

ERIC Educational Resources Information Center

Lai, Cheng Fei; Alonzo, Julie; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 4. Technical Report # 09-03

ERIC Educational Resources Information Center

Alonzo, Julie; Lai, Cheng Fei; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 7. Technical Report 0908

ERIC Educational Resources Information Center

Lai, Cheng Fei; Alonzo, Julie; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 8. Technical Report # 09-04

ERIC Educational Resources Information Center

Lai, Cheng Fei; Alonzo, Julie; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

Total factor productivity change in dairy farming: Empirical evidence from southern Chile.

PubMed

Moreira, Víctor H; Bravo-Ureta, Boris E

2016-10-01

Despite the importance of productivity growth, many studies carried out at the farm level focus primarily on the technical efficiency (TE) component of farm productivity. Therefore, the general purpose of this paper is to measure total factor productivity change and then to decompose this change into several distinct elements. The data were an unbalanced panel for the period from 2005 to 2010 containing 477 farms and 1,426 observations obtained from TODOAGRO, a farm-management center created in 1996 in the southern part of Chile. The region where the data come from accounts for 20% of the total milk processed in the country. Stochastic production frontiers along with the translog functional form were used to analyze total factor productivity change. The econometric evidence indicates that farms exhibit decreasing returns to size implying that costs of production rise as farm size increases, which suggests that the motivation for farm growth stems from the search for income rather than from lowering costs. The main results indicated that productivity gains through TE improvements are limited, with an average TE for the whole sample of 91.0%, and average technical efficiency change of 0.05% per year. By contrast, average technological progress at the sample mean was rather high at 1.90%, which suggests that additional investments in research and subsequent adoption of improved technologies would have a positive effect on productivity growth. The findings also revealed that farm size is not associated with productivity growth for the dairy farms in the sample. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Large area silicon sheet by EFG

NASA Technical Reports Server (NTRS)

1981-01-01

Progress was made in improving ribbon flatness and reducing stress, and in raising cell performance for 10 cm wide ribbon grown in single cartridge EFG furnaces. Optimization of growth conditions resulted in improved ribbon thickness uniformity at a thickness of 200 micron, grown at 4 cm/minute, and growth at this target speed is routinely achieved over periods of the order of one hour or more. With the improved ribbon flatness, fabrication of large area (50 cm2) cells is now possible, and 10 to 11% efficiencies were demonstrated on ribbon grown at 3.5 to 4 cm/minute. Factors limiting performance of the existing multiple ribbon furnace were identified, and growth system improvements implemented to help raise throughput rates and the time percentage of simultaneous three-ribbon growth. However, it is evident that major redesign of this furnace would be needed to overcome shortfalls in its ability to achieve the Technical Features Demonstration goals of 1980. It was decided to start construction of a new multiple ribbon furnace and to incorporate the desired improvements into its design. The construction of this furnace is completed.

Development and Validation of a Novel Scoring System for Predicting Technical Success of Chronic Total Occlusion Percutaneous Coronary Interventions: The PROGRESS CTO (Prospective Global Registry for the Study of Chronic Total Occlusion Intervention) Score.

PubMed

Christopoulos, Georgios; Kandzari, David E; Yeh, Robert W; Jaffer, Farouc A; Karmpaliotis, Dimitri; Wyman, Michael R; Alaswad, Khaldoon; Lombardi, William; Grantham, J Aaron; Moses, Jeffrey; Christakopoulos, Georgios; Tarar, Muhammad Nauman J; Rangan, Bavana V; Lembo, Nicholas; Garcia, Santiago; Cipher, Daisha; Thompson, Craig A; Banerjee, Subhash; Brilakis, Emmanouil S

2016-01-11

This study sought to develop a novel parsimonious score for predicting technical success of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) performed using the hybrid approach. Predicting technical success of CTO PCI can facilitate clinical decision making and procedural planning. We analyzed clinical and angiographic parameters from 781 CTO PCIs included in PROGRESS CTO (Prospective Global Registry for the Study of Chronic Total Occlusion Intervention) using a derivation and validation cohort (2:1 sampling ratio). Variables with strong association with technical success in multivariable analysis were assigned 1 point, and a 4-point score was developed from summing all points. The PROGRESS CTO score was subsequently compared with the J-CTO (Multicenter Chronic Total Occlusion Registry in Japan) score in the validation cohort. Technical success was 92.9%. On multivariable analysis, factors associated with technical success included proximal cap ambiguity (beta coefficient [b] = 0.88), moderate/severe tortuosity (b = 1.18), circumflex artery CTO (b = 0.99), and absence of "interventional" collaterals (b = 0.88). The resulting score demonstrated good calibration and discriminatory capacity in the derivation (Hosmer-Lemeshow chi-square = 2.633; p = 0.268, and receiver-operator characteristic [ROC] area = 0.778) and validation (Hosmer-Lemeshow chi-square = 5.333; p = 0.070, and ROC area = 0.720) subset. In the validation cohort, the PROGRESS CTO and J-CTO scores performed similarly in predicting technical success (ROC area 0.720 vs. 0.746, area under the curve difference = 0.026, 95% confidence interval = -0.093 to 0.144). The PROGRESS CTO score is a novel useful tool for estimating technical success in CTO PCI performed using the hybrid approach. Copyright © 2016 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

Picture archiving and communication system developments expected in the 1990s

NASA Astrophysics Data System (ADS)

Drew, Philip G.; Lorah, Lawrence D.; Lydon, Michael J.; Novak, Elliott D.

1993-01-01

Among the applications for high-bandwidth systems are medical picture archiving and communication systems (PACS). Viewed in the light of developments anticipated ten years ago when these systems were first discussed, progress has been disappointingly slow. However, with the recognition that teleradiology, digital archives, and computed radiography can be regarded as PAC subsystems, and that systems confined to a single modality can be regarded as mini-PACS, it becomes clear that development of PAC systems has made remarkable progress. Growing from modest size today, the markets for PAC systems and subsystems in the U.S. is likely to exceed $600 million by the end of the decade, a market of the same magnitude as those for CT, MRI, and catheterization lab equipment. This paper discusses the forces that have stimulated growth of PAC systems - among them, the opportunity to provide better service to patients and referring physicians, a chance to expand effective service area, and a possible solution to the ubiquitous problems of lost films - as well as the impediments that have retarded growth - among them, technical limitations, especially of the radiologists' workstations, and cost. A review of these forces allows prediction of likely developments in the 1990s.

Final report : for the period of December 1999 through November 30, 2000 : Florida Transit Training Program (1999/2000) : Florida Technical Assistance Program (1999/2000)

DOT National Transportation Integrated Search

2000-01-01

The following progress report is intended to highlight the significant activities of the Florida Transit Training Program and Florida Technical Assistant Program. The following progress report is intended to highlight the significant activities of th...

Annual progress report : for the period of January 2001 through December 2001 : Florida Transit Training Program (2001) : Florida Technical Assistance Program (2001)

DOT National Transportation Integrated Search

2001-01-01

The following progress report is intended to highlight the significant activities of the Florida Transit Training Program and Florida Technical Assistant Program for the 2001 year. Activities of the Florida Statewide Transit Training Program are pres...

Environmentally Responsible Aviation - Real Solutions for Environmental Challenges Facing Aviation

NASA Technical Reports Server (NTRS)

Collier, Fayette; Thomas, Russell; Burley, Casey; Nickol, Craig; Lee, Chi-Ming; Tong, Michael

2010-01-01

The combined reality of persistently strong growth in air traffic and the vital economic role of the air transport system result in continued demand for the progress of technology for the reduction of aircraft noise, emissions of oxides of nitrogen, and fuel burn. NASA s Environmentally Responsible Aviation (ERA) project has set aggressive goals in these three areas including a noise goal of 42 dB cumulative below the Stage 4 certification level. The goal for the reduction of oxides of nitrogen is 75% below the current standard. The fuel burn reduction goal is 50% below that of a current state-of-the-art aircraft. Furthermore, the overall goal of ERA is to mature technologies that will meet these goals simultaneously and with a timeframe of 2020 for technical readiness. This paper outlines the key technologies and the progress achieved to date toward the goals.

76 FR 64083 - Reliability Technical Conference; Notice of Technical Conference

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-17

... Technical Conference; Notice of Technical Conference Take notice that the Federal Energy Regulatory Commission will hold a Technical Conference on Tuesday, November 29, 2011, from 1 p.m. to 5 p.m. and... System. The conference will explore the progress made on the priorities for addressing risks to...

48 CFR 2052.211-70 - Preparation of technical reports.

Code of Federal Regulations, 2014 CFR

2014-10-01

....211-70 Preparation of technical reports. As prescribed at 2011.104-70(a), the contracting officer... Reports (JAN 1993) All technical reports required by Section C and all Technical Progress Reports required... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Preparation of technical...

48 CFR 2052.211-70 - Preparation of technical reports.

Code of Federal Regulations, 2012 CFR

2012-10-01

....211-70 Preparation of technical reports. As prescribed at 2011.104-70(a), the contracting officer... Reports (JAN 1993) All technical reports required by Section C and all Technical Progress Reports required... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Preparation of technical...

48 CFR 2052.211-70 - Preparation of technical reports.

Code of Federal Regulations, 2010 CFR

2010-10-01

....211-70 Preparation of technical reports. As prescribed at 2011.104-70(a), the contracting officer... Reports (JAN 1993) All technical reports required by Section C and all Technical Progress Reports required... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Preparation of technical...

48 CFR 2052.211-70 - Preparation of technical reports.

Code of Federal Regulations, 2013 CFR

2013-10-01

....211-70 Preparation of technical reports. As prescribed at 2011.104-70(a), the contracting officer... Reports (JAN 1993) All technical reports required by Section C and all Technical Progress Reports required... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Preparation of technical...

48 CFR 2052.211-70 - Preparation of technical reports.

Code of Federal Regulations, 2011 CFR

2011-10-01

....211-70 Preparation of technical reports. As prescribed at 2011.104-70(a), the contracting officer... Reports (JAN 1993) All technical reports required by Section C and all Technical Progress Reports required... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Preparation of technical...

A new look at the decomposition of agricultural productivity growth incorporating weather effects.

PubMed

Njuki, Eric; Bravo-Ureta, Boris E; O'Donnell, Christopher J

2018-01-01

Random fluctuations in temperature and precipitation have substantial impacts on agricultural output. However, the contribution of these changing configurations in weather to total factor productivity (TFP) growth has not been addressed explicitly in econometric analyses. Thus, the key objective of this study is to quantify and to investigate the role of changing weather patterns in explaining yearly fluctuations in TFP. For this purpose, we define TFP to be a measure of total output divided by a measure of total input. We estimate a stochastic production frontier model using U.S. state-level agricultural data incorporating growing season temperature and precipitation, and intra-annual standard deviations of temperature and precipitation for the period 1960-2004. We use the estimated parameters of the model to compute a TFP index that has good axiomatic properties. We then decompose TFP growth in each state into weather effects, technological progress, technical efficiency, and scale-mix efficiency changes. This approach improves our understanding of the role of different components of TFP in agricultural productivity growth. We find that annual TFP growth averaged 1.56% between 1960 and 2004. Moreover, we observe substantial heterogeneity in weather effects across states and over time.

A new look at the decomposition of agricultural productivity growth incorporating weather effects

PubMed Central

Bravo-Ureta, Boris E.; O’Donnell, Christopher J.

2018-01-01

Random fluctuations in temperature and precipitation have substantial impacts on agricultural output. However, the contribution of these changing configurations in weather to total factor productivity (TFP) growth has not been addressed explicitly in econometric analyses. Thus, the key objective of this study is to quantify and to investigate the role of changing weather patterns in explaining yearly fluctuations in TFP. For this purpose, we define TFP to be a measure of total output divided by a measure of total input. We estimate a stochastic production frontier model using U.S. state-level agricultural data incorporating growing season temperature and precipitation, and intra-annual standard deviations of temperature and precipitation for the period 1960–2004. We use the estimated parameters of the model to compute a TFP index that has good axiomatic properties. We then decompose TFP growth in each state into weather effects, technological progress, technical efficiency, and scale-mix efficiency changes. This approach improves our understanding of the role of different components of TFP in agricultural productivity growth. We find that annual TFP growth averaged 1.56% between 1960 and 2004. Moreover, we observe substantial heterogeneity in weather effects across states and over time. PMID:29466461

REACTOR PHYSICS QUARTERLY REPORT JANUARY, FEBRUARY, MARCH 1970

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schmid, L. C.; Clayton, E. D.; Heineman, R. E.

1970-05-01

The objective of the Reactor Physics Quarterly Report is to inform the scientific community in a timely manner of the technical progress made on the many phases of reactor physics work within the laboratory. The report contains brief technical discussions of accomplishments in all areas where significant progress has been made during the quarter.

Progress and prospects: gene therapy for performance and appearance enhancement.

PubMed

Kiuru, M; Crystal, R G

2008-03-01

While medical therapies aim at reversing, reducing or eliminating diseases, the goal of enhancements is to improve performance or appearance beyond normal levels. Distinction between the two interventions is not always clear as they often present as a continuum. Gene therapy typically aims at treating or preventing disease, but the technology can theoretically be employed for enhancement. Some of the gene therapy enhancement strategies include improving performance by increasing muscle mass, endurance, memory, and cognition and bettering appearance by controlling weight, height and hair growth. In addition to the technical challenges of making enhancement strategies safe and effective, genetic enhancement presents significant ethical/societal questions that must be addressed.

George A. Olah, Carbocation and Hydrocarbon Chemistry

Science.gov Websites

. Final Technical Report. [HF:BF{sub 2}/H{sub 2}] , DOE Technical Report, 1980 Superacid Catalyzed Coal Conversion Chemistry. 1st and 2nd Quarterly Technical Progress Reports, September 1, 1983-March 30, 1984 , DOE Technical Report, 1984 Superacid Catalyzed Coal Conversion Chemistry. Final Technical Report

HKHC Community Dashboard: design, development, and function of a Web-based performance monitoring system.

PubMed

Bors, Philip A; Kemner, Allison; Fulton, John; Stachecki, Jessica; Brennan, Laura K

2015-01-01

As part of Robert Wood Johnson Foundation's Healthy Kids, Healthy Communities (HKHC) national grant program, a technical assistance team designed the HKHC Community Dashboard, an online progress documentation and networking system. The Dashboard was central to HKHC's multimethod program evaluation and became a communication interface for grantees and technical assistance providers. The Dashboard was designed through an iterative process of identifying needs and priorities; designing the user experience, technical development, and usability testing; and applying visual design. The system was created with an open-source content management system and support for building an online community of users. The site developer trained technical assistance providers at the national program office and evaluators, who subsequently trained all 49 grantees. Evaluators provided support for Dashboard users and populated the site with the bulk of its uploaded tools and resource documents. The system tracked progress through an interactive work plan template, regular documentation by local staff and partners, and data coding and analysis by the evaluation team. Other features included the ability to broadcast information to Dashboard users via e-mail, event calendars, discussion forums, private messaging, a resource clearinghouse, a technical assistance diary, and real-time progress reports. The average number of Dashboard posts was 694 per grantee during the grant period. Technical assistance providers and grantees uploaded a total of 1304 resource documents. The Dashboard functions with the highest grantee satisfaction were its interfaces for sharing and progress documentation. A majority of Dashboard users (69%) indicated a preference for continued access to the Dashboard's uploaded resource documents. The Dashboard was a useful and innovative tool for participatory evaluation of a large national grant program. While progress documentation added some burden to local project staff, the system proved to be a useful resource-sharing technology.

Supply Chain Sustainability Analysis of Whole Algae Hydrothermal Liquefaction and Upgrading

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pegallapati, Ambica Koushik; Dunn, Jennifer B.; Frank, Edward D.

2015-04-01

The Department of Energy's Bioenergy Technology Office (BETO) collaborates with a wide range of institutions towards the development and deployment of biofuels and bioproducts. To facilitate this effort, BETO and its partner national laboratories develop detailed techno-economic assessments (TEA) of biofuel production technologies as part of the development of design cases and state of technology (SOT) analyses. A design case is a TEA that outlines a target case for a particular biofuel pathway. It enables preliminary identification of data gaps and research and development needs and provides goals and targets against which technology progress is assessed. On the other hand,more » an SOT analysis assesses progress within and across relevant technology areas based on actual experimental results relative to technical targets and cost goals from design cases and includes technical, economic, and environmental criteria as available. (SOT) analyses. A design case is a TEA that outlines a target case for a particular biofuel pathway. It enables preliminary identification of data gaps and research and development needs and provides goals and targets against which technology progress is assessed. On the other hand, an SOT analysis assesses progress within and across relevant technology areas based on actual experimental results relative to technical targets and cost goals from design cases and includes technical, economic, and environmental criteria as available. (SOT) analyses. A design case is a TEA that outlines a target case for a particular biofuel pathway. It enables preliminary identification of data gaps and research and development needs and provides goals and targets against which technology progress is assessed. On the other hand, an SOT analysis assesses progress within and across relevant technology areas based on actual experimental results relative to technical targets and cost goals from design cases and includes technical, economic, and environmental criteria as available.« less

Dip-coating process: Silicon sheet growth development for the large-area silicon sheet task of the low-cost silicon solar array project

NASA Technical Reports Server (NTRS)

Zook, J. D.; Heaps, J. D.; Maciolek, R. B.; Koepke, B. G.; Gutter, C. D.; Schuldt, S. B.

1977-01-01

The objective of this research program is to investigate the technical and economic feasibility of producing solar-cell-quality sheet silicon by coating one surface of carbonized ceramic substrates with a thin layer of large-grain polycrystalline silicon from the melt. The past quarter demonstrated significant progress in several areas. Seeded growth of silicon-on-ceramic (SOC) with an EFG ribbon seed was demonstrated. Different types of mullite were successfully coated with silicon. A new method of deriving minority carrier diffusion length, L sub n from spectral response measurements was evaluated. ECOMOD cost projections were found to be in good agreement with the interim SAMIS method proposed by JPL. On the less positive side, there was a decrease in cell performance which we believe to be due to an unidentified source of impurities.

Education, Industrialization and Technical Progress in Mexico. IIEP Research Report No. 6.

ERIC Educational Resources Information Center

Padua, Jorge

This report attempts to analyze the contributions of the educational system and job training programs to industrialization and technical progress in the Conubal zone of the Lower Balsas River of Mexico. The first of the study's three sections consists of two chapters that provide general background. Chapter 1, "Theories of Development and the…

Technical Adequacy and Acceptability of Curriculum-Based Measurement and the Measures of Academic Progress

ERIC Educational Resources Information Center

January, Stacy-Ann A.; Ardoin, Scott P.

2015-01-01

Curriculum-based measurement in reading (CBM-R) and the Measures of Academic Progress (MAP) are assessment tools widely employed for universal screening in schools. Although a large body of research supports the validity of CBM-R, limited empirical evidence exists supporting the technical adequacy of MAP or the acceptability of either measure for…

Annual Technical Progress Report for Emergency School Assistance Program, Title 45, 1970-71.

ERIC Educational Resources Information Center

Lindsey, Randall B.

This paper presents a technical progress report of two programs conducted with funds provided under the Emergency School Assistance Program. One, the Mobile Learning Unit, said to have been designed to measure changes in fourth and fifth grade students' self-concept in a reorganized desegregated school environment, focuses on whether a positive…

Third Progress and Information Report of the Vocational-Technical Education Consortium of States.

ERIC Educational Resources Information Center

Lee, Connie W.; And Others

This description of major activities and accomplishments of the Vocational-Technical Education Consortium of the States (V-TECS) since the second progress report of May, 1975, is designed to provide the reader with a basic understanding of the processes and procedures used by the consortium in achieving its major goal: The production of catalogs…

A PSFI-based analysis on the energy efficiency potential of China’s domestic passenger vehicles

NASA Astrophysics Data System (ADS)

Chen, Chuan; Ren, Huanhuan; Zhao, Dongchang

2017-01-01

In this article, China’s domestic passenger vehicles (excluding new energy vehicles) are categorized into two groups: local brand vehicles and vehicles manufactured by joint ventures. Performance-Size-Fuel economy Index (PSFI) will be applied to analyse the speed of technical progress and the future trends of these vehicles. In addition, a forecast on energy efficiency potential of domestic passenger vehicles from 2016 to 2020 will be made based on different Emphasis on Reducing Fuel Consumption (ERFC) scenarios. According to the study, if the process of technical progress continues at its current speed, domestic ICE passenger vehicles will hardly meet Phase IV requirements by 2020 even though companies contribute as much technical progress to fuel consumption reduction as possible.

Advanced Thermal Emission Imaging Systems Definition and Development

NASA Technical Reports Server (NTRS)

Blasius, Karl; Nava, David (Technical Monitor)

2002-01-01

Santa Barbara Remote Sensing (SBRS), Raytheon Company, is pleased to submit this quarterly progress report of the work performed in the third quarter of Year 2 of the Advanced THEMIS Project, July through September 2002. We review here progress in the proposed tasks. During July through September 2002 progress was made in two major tasks, Spectral Response Characterization and Flight Instrument Definition. Because of staffing problems and technical problems earlier in the program we have refocused the remaining time and budget on the key technical tasks. Current technical problems with a central piece of test equipment has lead us to request a 1 quarter extension to the period of performance. This request is being made through a separate letter independent of this report.

Virtual Worlds for Virtual Organizing

NASA Astrophysics Data System (ADS)

Rhoten, Diana; Lutters, Wayne

The members and resources of a virtual organization are dispersed across time and space, yet they function as a coherent entity through the use of technologies, networks, and alliances. As virtual organizations proliferate and become increasingly important in society, many may exploit the technical architecture s of virtual worlds, which are the confluence of computer-mediated communication, telepresence, and virtual reality originally created for gaming. A brief socio-technical history describes their early origins and the waves of progress followed by stasis that brought us to the current period of renewed enthusiasm. Examination of contemporary examples demonstrates how three genres of virtual worlds have enabled new arenas for virtual organizing: developer-defined closed worlds, user-modifiable quasi-open worlds, and user-generated open worlds. Among expected future trends are an increase in collaboration born virtually rather than imported from existing organizations, a tension between high-fidelity recreations of the physical world and hyper-stylized imaginations of fantasy worlds, and the growth of specialized worlds optimized for particular sectors, companies, or cultures.

2017 Publications Demonstrate Advancements in Wind Energy Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

In 2017, wind energy experts at the National Renewable Energy Laboratory (NREL) made significant strides to advance wind energy. Many of these achievements were presented in articles published in scientific and engineering journals and technical reports that detailed research accomplishments in new and progressing wind energy technologies. During fiscal year 2017, NREL wind energy thought leaders shared knowledge and insights through 45 journal articles and 25 technical reports, benefiting academic and national-lab research communities; industry stakeholders; and local, state, and federal decision makers. Such publications serve as important outreach, informing the public of how NREL wind research, analysis, and deploymentmore » activities complement advanced energy growth in the United States and around the world. The publications also illustrate some of the noteworthy outcomes of U.S. Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) and Laboratory Directed Research and Development funding, as well as funding and facilities leveraged through strategic partnerships and other collaborations.« less

PRECOG: a tool for automated extraction and visualization of fitness components in microbial growth phenomics.

PubMed

Fernandez-Ricaud, Luciano; Kourtchenko, Olga; Zackrisson, Martin; Warringer, Jonas; Blomberg, Anders

2016-06-23

Phenomics is a field in functional genomics that records variation in organismal phenotypes in the genetic, epigenetic or environmental context at a massive scale. For microbes, the key phenotype is the growth in population size because it contains information that is directly linked to fitness. Due to technical innovations and extensive automation our capacity to record complex and dynamic microbial growth data is rapidly outpacing our capacity to dissect and visualize this data and extract the fitness components it contains, hampering progress in all fields of microbiology. To automate visualization, analysis and exploration of complex and highly resolved microbial growth data as well as standardized extraction of the fitness components it contains, we developed the software PRECOG (PREsentation and Characterization Of Growth-data). PRECOG allows the user to quality control, interact with and evaluate microbial growth data with ease, speed and accuracy, also in cases of non-standard growth dynamics. Quality indices filter high- from low-quality growth experiments, reducing false positives. The pre-processing filters in PRECOG are computationally inexpensive and yet functionally comparable to more complex neural network procedures. We provide examples where data calibration, project design and feature extraction methodologies have a clear impact on the estimated growth traits, emphasising the need for proper standardization in data analysis. PRECOG is a tool that streamlines growth data pre-processing, phenotypic trait extraction, visualization, distribution and the creation of vast and informative phenomics databases.

Index to Nuclear Safety. A technical progress review by chronology, permuted title, and author. Vol. 11, No. 1--Vol. 17, No. 6

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cottrell, W.B.; Klein, A.

1977-02-23

This index to Nuclear Safety covers articles in Nuclear Safety Vol. 11, No. 1 (Jan.-Feb. 1970), through Vol. 17, No. 6 (Nov.-Dec. 1976). The index includes a chronological list of articles (including abstract) followed by KWIC and Author Indexes. Nuclear Safety, a bimonthly technical progress review prepared by the Nuclear Safety Information Center, covers all safety aspects of nuclear power reactors and associated facilities. The index lists over 350 technical articles in the last six years of publication.

[Address Given at the Regional Junior College Recreation Education Institute, American River College, September 25, 1969.

ERIC Educational Resources Information Center

Lutzin, Sidney G.

The United States has made striking technical advances in recent years, but there has not been comparable progress in social services. Greater affluence and leisure for some have been one result of technical progress, but problems of poverty and urban development are more pressing. New developments to improve the condition of society can be…

THE DEVELOPMENT OF PRE-VOCATIONAL EDUCATION LITERACY COURSES FOR USE WITH COMPUTER ASSISTED INSTRUCTION OF DISADVANTAGED YOUTH AND ADULTS. TECHNICAL PROGRESS REPORT.

ERIC Educational Resources Information Center

HANKIN, EDWARD K.; AND OTHERS

THIS TECHNICAL PROGRESS REPORT COVERS THE FIRST THREE MONTHS OF A PROJECT TO DEVELOP COMPUTER ASSISTED PREVOCATIONAL READING AND ARITHMETIC COURSES FOR DISADVANTAGED YOUTHS AND ADULTS. DURING THE FIRST MONTH OF OPERATION, PROJECT PERSONNEL CONCENTRATED ON SUCH ADMINISTRATIVE MATTERS AS TRAINING STAFF AND PREPARING FACILITIES. AN ARITHMETIC PROGRAM…

Generation and focusing of pulsed intense ion beams. Technical progress report, 20 August 1981-30 September 1982

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hammer, D.A.; Kusse, B.R.; Sudan, R.N.

1983-07-01

The progress on this contract is described in two parts. The first deals with the technical operation of the LION accelerator which is the exact equivalent to one line of PBFA-I. The second part is concerned with the experimental results on the ion diode mounted at the front end of the LION accelerator.

Project LIFE--Language Improvement to Facilitate Education. (Technical Progress Report; Third Quarter; March 1, 1974-May 31, 1974).

ERIC Educational Resources Information Center

National Foundation for the Improvement of Education, Washington, DC.

Reported is the third quarter, fiscal year 1974 (March 1, 1974-May 31, 1974) technical progress of Project LIFE (Language Improvement to Facilitate Education), toward developing an instructional system in which filmstrips in the areas of perceptual training, perceptual thinking, and language/reading are used to assist hearing impaired children in…

Monitoring the Durability Performance of Concrete in Nuclear Waste Containment. Technical Progress Report No. 4

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ulm, Franz-Josef

2000-06-30

OAK-B135 Monitoring the Durability Performance of Concrete in Nuclear Waste Containment. Technical Progress Report No. 4. The analysis of the effect of cracks on the acceleration of the calcium leaching process of cement-based materials has been pursued. During the last period (Technical Progress Report No 3), we have introduced a modeling accounting for the high diffusivity of fractures in comparison with the weak solid material diffusivity. It has been shown through dimensional and asymptotic analysis that small fractures do not significantly accelerate the material aging process. This important result for the overall structural aging kinetics of containment structure has beenmore » developed in a paper submitted to the international journal ''Transport in Porous Media''.« less

Monitoring urban expansion and its effects on land use and land cover changes in Guangzhou city, China.

PubMed

Wu, Yanyan; Li, Shuyuan; Yu, Shixiao

2016-01-01

There are widespread concerns about urban sprawl in China. In response, modeling and assessing urban expansion and subsequent land use and land cover (LULC) changes have become important approaches to support decisions about appropriate development and land resource use. Guangzhou, a major metropolitan city in South China, has experienced rapid urbanization and great economic growth in the past few decades. This study applied a series of Landsat images to assess the urban expansion and subsequent LULC changes over 35 years, from 1979 to 2013. From start to end, urban expansion increased by 1512.24 km(2) with an annual growth rate of 11.25 %. There were four stages of urban growth: low rates from 1979 to 1990, increased rates from 1990 to 2001, high rates from 2001 to 2009, and steady increased rates from 2009 to 2013. There were also three different urban growth types in these different stages: edge-expansion growth, infilling growth, and spontaneous growth. Other land cover, such as cropland, forest, and mosaics of cropland and natural vegetation, were severely impacted as a result. To analyze these changes, we used landscape metrics to characterize the changes in the spatial patterns across the Guangzhou landscape and the impacts of urban growth on other types of land cover. The significant changes in LULC and urban expansion were highly correlated with economic development, population growth, technical progress, policy elements, and other similar indexes.

Probabilistic Mass Growth Uncertainties

NASA Technical Reports Server (NTRS)

Plumer, Eric; Elliott, Darren

2013-01-01

Mass has been widely used as a variable input parameter for Cost Estimating Relationships (CER) for space systems. As these space systems progress from early concept studies and drawing boards to the launch pad, their masses tend to grow substantially, hence adversely affecting a primary input to most modeling CERs. Modeling and predicting mass uncertainty, based on historical and analogous data, is therefore critical and is an integral part of modeling cost risk. This paper presents the results of a NASA on-going effort to publish mass growth datasheet for adjusting single-point Technical Baseline Estimates (TBE) of masses of space instruments as well as spacecraft, for both earth orbiting and deep space missions at various stages of a project's lifecycle. This paper will also discusses the long term strategy of NASA Headquarters in publishing similar results, using a variety of cost driving metrics, on an annual basis. This paper provides quantitative results that show decreasing mass growth uncertainties as mass estimate maturity increases. This paper's analysis is based on historical data obtained from the NASA Cost Analysis Data Requirements (CADRe) database.

Examination of Faculty Expectations of Technical College Administrators as an Important Factor in High Performing Environments

ERIC Educational Resources Information Center

Dupuis, Phyllis A.

2009-01-01

Popular thought supports the notion that faculty expectations of technical college administrators appear to be linked to the success or failure of an institution at accomplishing its mission. These expectations provide the basis for the development of relationships that foster the growth of technical training and thus the growth of a skilled…

Department of Clinical Investigation Annual Research Progress Report, Fiscal Year 1984. Volume 1,

DTIC Science & Technology

1984-10-01

on a low dosage of medication . Technical Approach: None. Progress: The placebo has not been received from the company. Since the drug company...determine the effect of high dose Ar-C intensification therapy on the -. incidence of CNS relapse. - Technical Approach: All patients with a new...Enrolled to Date: 7 Date of Periodic Review Results Objective(s): To determine the incidence of

Cobb Angle Progression in Adolescent Scoliosis Begins at the Intervertebral Disc

PubMed Central

Will, Ryan E; Stokes, Ian A; Qiu, Xing; Walker, Matthew R.; Sanders, James O

2009-01-01

Study Design Longitudinal radiographic study of patients with progressive idiopathic scoliosis. Objective To determine the relative contributions of vertebral and disc wedging to the increase in Cobb angle during 3 phases of adolescent skeletal growth and maturation. Summary of Background Data Both disc wedging and vertebral body wedging are found in progressive scoliosis, but their relative contribution to curve progression over time is unknown. Which occurs first is important for understanding how scoliosis progresses and for developing methods to halt progression. Previous studies have not properly identified maturity and provide conflicting results. Methods Eighteen girls were followed through their adolescent growth spurt with serial spine and hand skeletal age radiographs. Each Cobb angle was divided into disc wedge angles and vertebral wedge angles. The corresponding hand radiographs provided a measure of maturity level, the Digital Skeletal Age (DSA). The disc versus bone contributions to the Cobb angle were then compared during 3 growth phases: prior to the growth spurt, during the growth spurt and after the growth spurt. Significance of relative changes was assessed with the Wilcoxon two-sided mean rank test. Results Prior to the growth spurt, there was no difference in relative contributions of the disc and the bone (3° vs 0°, p=0.38) to curve progression. During the growth spurt, the mean disc component progressed significantly more than that of the vertebrae (15° vs 0°, p=0.0002). This reversed following the growth spurt with the vertebral component progressing more than the disc (10° vs 0°, p=0.01). Conclusion Adolescent idiopathic scoliosis initially increases through disc wedging during the rapid growth spurt with progressive vertebral wedging occurring later. PMID:19940737

Progress, Exponential Growth and Post-Growth Education

ERIC Educational Resources Information Center

Irwin, Ruth

2017-01-01

Teleological progress is the underlying motif of modern culture, and informs education, innovation, and economic development. Progress includes a gradual increase in consumerism. Since the 1940s, the Keynesian Settlement and its embedded belief in progress is legislated in exponential 2-3% economic growth. Unfortunately, climate change is a direct…

[Living without atomic power? Carl Friedrich von Weizsäcker as expert in the nuclear energy debate of the 1970's].

PubMed

Seefried, Elke

2014-01-01

Carl Friedrich von Weizsäcker crossed the boundaries separating science, politics and the public sphere. In this he was led by the conviction that scientists in the modern 'technical age' are responsible for consequences resulting from their applied knowledge. Weizsäcker tried to introduce his knowledge into the policy process by advising politicians or by using the public sphere, thus applying pressure on politics. This was not only true for the 'Göttinger Erklärung' in 1957 but also for his engagement in the nuclear energy debate of the 1970s. Influenced by the 'Limits to Growth' discourse, Weizsäcker more and more gravitated towards an ecological world view and increasingly questioned material growth as well as a techno-scientific based understanding of progress. Weizsäcker thought about risks of the technical age in general and of the use of nuclear energy in particular. In the light of a growing fragmentation of scientific authority, Weizsäcker revealed uncertainty as he became fully aware that expertise cannot be based on scientific reason and cannot code the problems in terms of truth, but is inextricably linked with value spheres and contingencies. Nevertheless, his expertise was utilized as he encouraged parts of the Social Democratic Party (SPD) around Erhard Eppler to think about alternatives in energy policy.

48 CFR 2011.104-70 - NRC Clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Technical Reports, when deliverables include a technical report. (b) The contracting officer shall insert the clause at 2052.211-71 Technical Progress Report, in all solicitations and contracts except— (1...) The contracting officer shall insert the clause at 2052.211-72 Financial Status Report, in applicable...

48 CFR 2011.104-70 - NRC Clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Technical Reports, when deliverables include a technical report. (b) The contracting officer shall insert the clause at 2052.211-71 Technical Progress Report, in all solicitations and contracts except— (1...) The contracting officer shall insert the clause at 2052.211-72 Financial Status Report, in applicable...

48 CFR 2011.104-70 - NRC Clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Technical Reports, when deliverables include a technical report. (b) The contracting officer shall insert the clause at 2052.211-71 Technical Progress Report, in all solicitations and contracts except— (1...) The contracting officer shall insert the clause at 2052.211-72 Financial Status Report, in applicable...

48 CFR 2011.104-70 - NRC Clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Technical Reports, when deliverables include a technical report. (b) The contracting officer shall insert the clause at 2052.211-71 Technical Progress Report, in all solicitations and contracts except— (1...) The contracting officer shall insert the clause at 2052.211-72 Financial Status Report, in applicable...

48 CFR 2011.104-70 - NRC Clauses.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Technical Reports, when deliverables include a technical report. (b) The contracting officer shall insert the clause at 2052.211-71 Technical Progress Report, in all solicitations and contracts except— (1...) The contracting officer shall insert the clause at 2052.211-72 Financial Status Report, in applicable...

32 CFR 203.17 - Technical assistance provider reporting requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Technical assistance provider reporting requirements. 203.17 Section 203.17 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY... technical assistance provider shall submit progress reports, financial status reports, materials prepared...

32 CFR 203.17 - Technical assistance provider reporting requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Technical assistance provider reporting requirements. 203.17 Section 203.17 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY... technical assistance provider shall submit progress reports, financial status reports, materials prepared...

32 CFR 203.17 - Technical assistance provider reporting requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 2 2013-07-01 2013-07-01 false Technical assistance provider reporting requirements. 203.17 Section 203.17 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY... technical assistance provider shall submit progress reports, financial status reports, materials prepared...

32 CFR 203.17 - Technical assistance provider reporting requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 2 2011-07-01 2011-07-01 false Technical assistance provider reporting requirements. 203.17 Section 203.17 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY... technical assistance provider shall submit progress reports, financial status reports, materials prepared...

32 CFR 203.17 - Technical assistance provider reporting requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 2 2012-07-01 2012-07-01 false Technical assistance provider reporting requirements. 203.17 Section 203.17 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY... technical assistance provider shall submit progress reports, financial status reports, materials prepared...

ISABELLE: a progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hahn, H

This paper discusses the ISABELLE project, which has the objective of constructing a high-energy proton colliding beam facility at Brookhaven National Laboratory. The major technical features of the intersecting storage accelerators with their projected performance are described. Application of over 1000 superconducting magnets in the two rings represents the salient characteristic of the machine. The status of the entire project, the technical progress made so far, and difficulties encountered are reviewed.

Final Technical Progress Report: Development of Low-Cost Suspension Heliostat; December 7, 2011 - December 6, 2012

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bender, W.

2013-01-01

Final technical progress report of SunShot Incubator Solaflect Energy. The project succeeded in demonstrating that the Solaflect Suspension Heliostat design is viable for large-scale CSP installations. Canting accuracy is acceptable and is continually improving as Solaflect improves its understanding of this design. Cost reduction initiatives were successful, and there are still many opportunities for further development and further cost reduction.

Early detection: the impact of genomics.

PubMed

van Lanschot, M C J; Bosch, L J W; de Wit, M; Carvalho, B; Meijer, G A

2017-08-01

The field of genomics has shifted our view on disease development by providing insights in the molecular and functional processes encoded in the genome. In the case of cancer, many alterations in the DNA accumulate that enable tumor growth or even metastatic dissemination. Identification of molecular signatures that define different stages of progression towards cancer can enable early tumor detection. In this review, the impact of genomics will be addressed using early detection of colorectal cancer (CRC) as an example. Increased understanding of the adenoma-to-carcinoma progression has led to the discovery of several diagnostic biomarkers. This combined with technical advancements, has facilitated the development of molecular tests for non-invasive early CRC detection in stool and blood samples. Even though several tests have already made it to clinical practice, sensitivity and specificity for the detection of precancerous lesions still need improvement. Besides the diagnostic qualities, also the accuracy of the intermediate endpoint is an important issue on how the effectiveness of a novel test is perceived. Here, progression biomarkers may provide a more precise measure than the currently used morphologically based features. Similar developments in biomarker use for early detection have taken place in other cancer types.

Measurement of solids motion in gas-fluidized beds. Technical progress report, 1 October 1982-31 December 1982

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, M.M.; Chao, B.T.

This technical progress report covers the progress made during the fifth quarter of the project entitled Measurements of Solids Motion in Gas Fluidized Beds under Grant No. DOE-F22-81PC40804 during the period 1 October through 31 December 1982. The research concerns the measurement of solids particle velocity distribution and residence time distribution using the Computer-Aided Particle Tracking Facility (CAPTF) at the University of Illinois at Urbana-Champaign. The experimental equipment and measuring methods used to determine particle size distribution and particle motion and the results obtained are presented.

Poverty and mortality among the elderly: measurement of performance in 33 countries 1960-92.

PubMed

Wang, J; Jamison, D T; Bos, E; Vu, M T

1997-10-01

This paper analyses the effect of income and education on life expectancy and mortality rates among the elderly in 33 countries for the period 1960-92 and assesses how that relationship has changed over time as a result of technical progress. Our outcome variables are life expectancy at age 60 and the probability of dying between age 60 and age 80 for both males and females. The data are from vital-registration based life tables published by national statistical offices for several years during this period. We estimate regressions with determinants that include GDP per capita (adjusted for purchasing power), education and time (as a proxy for technical progress). As the available measure of education failed to account for variation in life expectancy or mortality at age 60, our reported analyses focus on a simplified model with only income and time as predictors. The results indicate that, controlling for income, mortality rates among the elderly have declined considerably over the past three decades. We also find that poverty (as measured by low average income levels) explains some of the variation in both life expectancy at age 60 and mortality rates among the elderly across the countries in the sample. The explained amount of variation is more substantial for females than for males. While poverty does adversely affect mortality rates among the elderly (and the strength of this effect is estimated to be increasing over time), technical progress appears far more important in the period following 1960. Predicted female life expectancy (at age 60) in 1960 at the mean income level in 1960 was, for example 18.8 years; income growth to 1992 increased this by an estimated 0.7 years, whereas technical progress increased it by 2.0 years. We then use the estimated regression results to compare country performance on life expectancy of the elderly, controlling for levels of poverty (or income), and to assess how performance has varied over time. High performing countries, on female life expectancy at age 60, for the period around 1990, included Chile (1.0 years longer life expectancy), China (1.7 years longer), France (2.0 years longer), Japan (1.9 years longer), and Switzerland (1.3 years longer). Poorly performing countries included Denmark (1.1 years shorter life expectancy than predicted from income), Hungary (1.4 years shorter), Iceland (1.2 years shorter), Malaysia (1.6 years shorter), and Trinidad and Tobago (3.9 years shorter). Chile and Switzerland registered major improvements in relative performance over this period; Norway, Taiwan and the USA, in contrast showed major declines in performance between 1980 and the early 1990s.

The 1996 NAEP Technical Report.

ERIC Educational Resources Information Center

Allen, Nancy L.; Carlson, James E.; Zelenak, Christine A.

This report documents the design, administration, and data analysis procedure of the National Assessment of Education Progress (NAEP) for 1996. It indicates the technical decisions that were made and the rationale behind them. Detailed substantive findings are not presented in this report. These chapters provide technical information about the…

Economic impact of stimulated technological activity. Part 1: Overall economic impact of technological progress: Its measurement

NASA Technical Reports Server (NTRS)

1971-01-01

Investigations were performed at the national economic level to explore the aggregate effects of technological progress on economic growth. Inadequacies in existing marco-economic yardsticks forced the study to focus on the cost savings effects achieved through technological progress. The central questions discussed in this report cover: (1) role of technological progress in economic growth, (2) factors determining the rate of economic growth due to technological progress; (3) quantitative measurements of relationships between technological progress, its determinants, and subsequent economic growth; and (4) effects of research and development activities of the space program. For Part 2, see N72-32174.

Lincoln County nuclear waste project. Quarterly progress report, October 1, 1991--December 31, 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-03-01

This document included the following three progress reports to the Yucca Mountain Project Office on radioactive waste storage in Lincoln County, Nevada: financial status report; federal cash transactions report; and technical progress report.

Lincoln County nuclear waste project. Quarterly progress report, January 1, 1992--March 31, 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-03-01

This document included the following three progress reports to the Yucca Mountain Project Office on radioactive waste storage in Lincoln County, Nevada: financial status report; federal cash transactions report; and technical progress report.

Lincoln County nuclear waste project quarterly progress report, April 1, 1992--June 30, 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-03-01

This document included the following three progress reports to the Yucca Mountain Project Office on radioactive waste storage in Lincoln County, Nevada: financial status report; federal cash transactions report; and technical progress report.

Index to Nuclear Safety: a technical progress review by chronology, permuted title, and author, Volume 18 (1) through Volume 22 (6)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cottrell, W.B.; Passiakos, M.

This index to Nuclear Safety covers articles published in Nuclear Safety, Volume 18, Number 1 (January-February 1977) through Volume 22, Number 6 (November-December 1981). The index is divided into three section: a chronological list of articles (including abstracts), a permuted-title (KWIC) index, and an author index. Nuclear Safety, a bimonthly technical progress review prepared by the Nuclear Safety Information Center, covers all safety aspects of nuclear power reactors and associated facilities. Over 300 technical articles published in Nuclear Safety in the last 5 years are listed in this index.

77 FR 16250 - Notice of Proposed Information Collection for Public Comment; Office of Native American Programs...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-20

... Information Collection for Public Comment; Office of Native American Programs (ONAP) Training and Technical... subject proposal. The data required by Office of Native American Programs Training and Technical... progress. The data identifies needs, outputs and outcomes of the training and technical assistance. DATES...

Discovery of functional monoclonal antibodies targeting G-protein-coupled receptors and ion channels.

PubMed

Wilkinson, Trevor C I

2016-06-15

The development of recombinant antibody therapeutics is a significant area of growth in the pharmaceutical industry with almost 50 approved monoclonal antibodies on the market in the US and Europe. Despite this growth, however, certain classes of important molecular targets have remained intractable to therapeutic antibodies due to complexity of the target molecules. These complex target molecules include G-protein-coupled receptors and ion channels which represent a large potential target class for therapeutic intervention with monoclonal antibodies. Although these targets have typically been addressed by small molecule approaches, the exquisite specificity of antibodies provides a significant opportunity to provide selective modulation of these target proteins. Given this opportunity, substantial effort has been applied to address the technical challenges of targeting these complex membrane proteins with monoclonal antibodies. In this review recent progress made in the strategies for discovery of functional monoclonal antibodies for these challenging membrane protein targets is addressed. © 2016 The Author(s). published by Portland Press Limited on behalf of the Biochemical Society.

Environmentally Responsible Aviation (ERA) Project - N+2 Advanced Vehicle Concepts Study and Conceptual Design of Subscale Test Vehicle (STV) Final Report

NASA Technical Reports Server (NTRS)

Bonet, John T.; Schellenger, Harvey G.; Rawdon, Blaine K.; Elmer, Kevin R.; Wakayama, Sean R.; Brown, Derrell L.; Guo, Yueping

2011-01-01

NASA has set demanding goals for technology developments to meet national needs to improve fuel efficiency concurrent with improving the environment to enable air transportation growth. A figure shows NASA's subsonic transport system metrics. The results of Boeing ERA N+2 Advanced Vehicle Concept Study show that the Blended Wing Body (BWB) vehicle, with ultra high bypass propulsion systems have the potential to meet the combined NASA ERA N+2 goals. This study had 3 main activities. 1) The development of an advanced vehicle concepts that can meet the NASA system level metrics. 2) Identification of key enabling technologies and the development of technology roadmaps and maturation plans. 3) The development of a subscale test vehicle that can demonstrate and mature the key enabling technologies needed to meet the NASA system level metrics. Technology maturation plans are presented and include key performance parameters and technical performance measures. The plans describe the risks that will be reduced with technology development and the expected progression of technical maturity.

Developments in Technical Education in the British Caribbean, 1940-60.

ERIC Educational Resources Information Center

Pemberton, S. Macpherson

The paper discusses developments in technical education in the British West Indies from 1940-1960 emphasizing the relation between education and economic development. The objective is to analyze the economic basis of progress in technical education. The document is presented in four chapters. Chapter I summarizes historical background prior to…

Programs of Study: Year 2 Joint Technical Report. Research Snapshot

ERIC Educational Resources Information Center

National Research Center for Career and Technical Education, 2010

2010-01-01

In January 2010, the National Research Center for Career and Technical Education (NRCCTE) issued a progress report on three studies being conducted by the Center that examine the implementation and outcomes of Programs of Study (POS), which were required in the 2006 reauthorization of the federal legislation for career and technical education…

Proceedings: Computer Science and Data Systems Technical Symposium, volume 1

NASA Technical Reports Server (NTRS)

Larsen, Ronald L.; Wallgren, Kenneth

1985-01-01

Progress reports and technical updates of programs being performed by NASA centers are covered. Presentations in viewgraph form are included for topics in three categories: computer science, data systems and space station applications.

Annual Progress Report (17th) and 1992-97 Renewal Proposal Interactive Graphics for Molecular Studies

DTIC Science & Technology

1991-01-24

Molecular Graphics, vol. 6, No. 4 (Dec. 1988), p. 223. Turk, Greg, "Interactive Collision Detection for Molecular Graphics," M.S. thesis , UNC-Chapel Hill...Problem," Master’s thesis , UNC Department of Computer Science Technical Report #TR87-013, May 1987. Pique, ME., "Technical Trends in Molecular Graphics...AD-A236 598 Seventeenth Annual Progress Report and 1992-97 Renewal Proposal Interactive Graphics for Molecular Studies TR91-020 January 24, 1991 red

Enhanced oil recovery utilizing high-angle wells in the Frontier Formation, Badger Basin Field, Park County, Wyoming. Quarterly technical progress report, 1 March 1993--30 June 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fortmann, R.G.; Walker, J.P.

1993-07-10

Sierra Energy Company`s targeted goals during the third quarter of this Cooperative Agreement included the following objectives from the Statement of Work: in Phase 2A, completion of subtask 2.1.2--acquire best possible field data in the 3-D seismic program; and initiation of Subtask 2.1.3--process acquired 3-D seismic data. Technical progress is described for these tasks.

10 CFR 603.1100 - Contracting officer's post-award responsibilities.

Code of Federal Regulations, 2011 CFR

2011-01-01

... technical progress, financial status, and future program plans. (b) Tracking and processing of reports... progress reports, and patent reports. (c) Handling payment requests and related matters. For a TIA using advance payments, that includes reviews of progress to verify that there is continued justification for...

7 CFR 3402.23 - Documentation of progress on funded projects.

Code of Federal Regulations, 2011 CFR

2011-01-01

... the academic program due to unsatisfactory academic progress; or voluntarily withdraws from the Fellowship or the academic program. If a Fellow has not completed all degree requirements at the end of the... database contains narrative project information, progress/impact statements, and final technical reports...

7 CFR 3402.23 - Documentation of progress on funded projects.

Code of Federal Regulations, 2014 CFR

2014-01-01

... the academic program due to unsatisfactory academic progress; or voluntarily withdraws from the Fellowship or the academic program. If a Fellow has not completed all degree requirements at the end of the... database contains narrative project information, progress/impact statements, and final technical reports...

7 CFR 3402.23 - Documentation of progress on funded projects.

Code of Federal Regulations, 2012 CFR

2012-01-01

... the academic program due to unsatisfactory academic progress; or voluntarily withdraws from the Fellowship or the academic program. If a Fellow has not completed all degree requirements at the end of the... database contains narrative project information, progress/impact statements, and final technical reports...

7 CFR 3402.23 - Documentation of progress on funded projects.

Code of Federal Regulations, 2013 CFR

2013-01-01

... the academic program due to unsatisfactory academic progress; or voluntarily withdraws from the Fellowship or the academic program. If a Fellow has not completed all degree requirements at the end of the... database contains narrative project information, progress/impact statements, and final technical reports...

NAEP 1999 Long-Term Trend Technical Analysis Report: Three Decades of Student Performance. NCES 2005-484

ERIC Educational Resources Information Center

Allen, Nancy L.; McClellan, Catherine A.; Stoeckel, Joan J.

2005-01-01

This report provides an update to the technical analysis procedures documenting the 1996 National Assessment of Educational Progress (NAEP) as presented in "The NAEP 1996 Technical Report" (Allen, Carlson, and Zelenak, 1999). It describes how the 1999 long-term trend data were incorporated into the trend analyses. Since no national main…

A New Stage in the Development of Secondary Vocational-Technical Schools

ERIC Educational Resources Information Center

Sedakov, V.

1977-01-01

Recommends that projected growth in the technical-vocational sector of education in the Soviet Union be accompanied by qualitative improvements in areas of political socialization, cultural transmission, and technical development. (Author/DB)

Technologies for diagnosis and treatment of acute stroke

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fitch, J.P.

1998-02-09

From October 1994 to June 1997, a multidisciplinary team of scientists and engineers at Lawrence Livermore National Laboratory were funded through LDRD to develop and integrate technologies for diagnosis and treatment of acute stroke. The project was summarized in a Science and Technology Review article `Brain Attack` that appeared in June 1997 and again in the Center for Healthcare Technologies Report (UCRL-LR-124761). This article is the best overview of the project, epidemiology of stroke and technical progress. Most of the technical progress has been documented in conference papers and presentations and refereed journal articles. Additional technical publication can be expectedmore » as our remaining patent applications progress through the US Patent and Trademark Office. The purpose of this report is to provide an appropriate introduction and organization to the numerous publications so that interested readers can quickly find information. Because there is no documentation for the history of this project, this report provides a summary. It also provides the final status report for the LDRD funding.« less

Proceedings: Computer Science and Data Systems Technical Symposium, volume 2

NASA Technical Reports Server (NTRS)

Larsen, Ronald L.; Wallgren, Kenneth

1985-01-01

Progress reports and technical updates of programs being performed by NASA centers are covered. Presentations in viewgraph form, along with abstracts, are included for topics in three catagories: computer science, data systems, and space station applications.

Phosphorene: Fabrication, properties, and applications

DOE PAGES

Kou, Liangzhi; Chen, Changfeng; Smith, Sean C.

2015-06-24

Phosphorene, the single- or few-layer form of black phosphorus, was recently rediscovered as a two-dimensional layered material holding great promise for applications in electronics and optoelectronics. Research into its fundamental properties and device applications has since seen exponential growth. In this Perspective, we review recent progress in phosphorene research, touching upon topics on fabrication, properties, and applications; we also discuss challenges and future research directions. We highlight the intrinsically anisotropic electronic, transport, optoelectronic, thermoelectric, and mechanical properties of phosphorene resulting from its puckered structure in contrast to those of graphene and transition-metal dichalcogenides. The facile fabrication and novel properties ofmore » phosphorene have inspired design and demonstration of new nanodevices; however, further progress hinges on resolutions to technical obstructions like surface degradation effects and nonscalable fabrication techniques. We also briefly describe the latest developments of more sophisticated design concepts and implementation schemes that address some of the challenges in phosphorene research. As a result, it is expected that this fascinating material will continue to offer tremendous opportunities for research and development for the foreseeable future.« less

[Research progress on the dual-mulching of ridge and furrow technology in dry farming regions of northern China: A review.

PubMed

Li, Rong; Hou, Xian Qing; Wang, Xiao Min; Jia, Zhi Kuan; Han, Qing Fang

2016-04-22

The precipitation exiguity and water deficiency are the major factors limiting crop growth in dry farming regions of northern China. Dual-mulching of ridges and furrows, which have been widely concerned both domestically and internationally, could increase the utilization efficiency of precipitation and crop yield. In this paper, we reviewed the concept and model of dual-mulching of ridges and furrows, its supporting farm machinery and implements as well as its ecological effects on soil and crops. Based on the current research progress of cultivation techniques using harvested rainfall in ridge and furrow, priority of future research aspects of the dual-mulching of ridges and furrows were suggested as follows: 1) to establish the suitable ridge-furrow ratios for different crops in different types of dry farming regions of northern China; 2) to pay more attention to the study of coupling effects of soil moisture with temperature, fertility and other factors; 3) to explore better environment-friendly mulching materials; 4) to enhance the research on technical evaluation and popularization, and the design of supporting farm machinery and implements.

A study on operation efficiency evaluation based on firm's financial index and benchmark selection: take China Unicom as an example

NASA Astrophysics Data System (ADS)

Wu, Zu-guang; Tian, Zhan-jun; Liu, Hui; Huang, Rui; Zhu, Guo-hua

2009-07-01

Being the only listed telecom operators of A share market, China Unicom has always been attracted many institutional investors under the concept of 3G recent years,which itself is a great technical progress expectation.Do the institutional investors or the concept of technical progress have signficant effect on the improving of firm's operating efficiency?Though reviewing the documentary about operating efficiency we find that schoolars study this problem useing the regress analyzing based on traditional production function and data envelopment analysis(DEA) and financial index anayzing and marginal function and capital labor ratio coefficient etc. All the methods mainly based on macrodata. This paper we use the micro-data of company to evaluate the operating efficiency.Using factor analyzing based on financial index and comparing the factor score of three years from 2005 to 2007, we find that China Unicom's operating efficiency is under the averge level of benchmark corporates and has't improved under the concept of 3G from 2005 to 2007.In other words,institutional investor or the conception of technical progress expectation have faint effect on the changes of China Unicom's operating efficiency. Selecting benchmark corporates as post to evaluate the operating efficiency is a characteristic of this method ,which is basicallly sipmly and direct.This method is suit for the operation efficiency evaluation of agriculture listed companies because agriculture listed also face technical progress and marketing concept such as tax-free etc.

Decontamination Systems Information and Research Program. Quarterly technical progress report, January 1--March 31, 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-05-01

West Virginia University (WVU) and the US DOE Morgantown Energy Technology Center (METC) entered into a Cooperative Agreement on August 29, 1992 entitled ``Decontamination Systems Information and Research Programs.`` Stipulated within the Agreement is the requirement that WVU submit to METC a series of Technical Progress Reports on a quarterly basis. This report comprises the first Quarterly Technical Progress Report for Year 2 of the Agreement. This report reflects the progress and/or efforts performed on the sixteen (16) technical projects encompassed by the Year 2 Agreement for the period of January 1 through March 31, 1994. In situ bioremediation ofmore » chlorinated organic solvents; Microbial enrichment for enhancing in-situ biodegradation of hazardous organic wastes; Treatment of volatile organic compounds (VOCs) using biofilters; Drain-enhanced soil flushing (DESF) for organic contaminants removal; Chemical destruction of chlorinated organic compounds; Remediation of hazardous sites with steam reforming; Soil decontamination with a packed flotation column; Use of granular activated carbon columns for the simultaneous removal of organics, heavy metals, and radionuclides; Monolayer and multilayer self-assembled polyion films for gas-phase chemical sensors; Compact mercuric iodide detector technology development; Evaluation of IR and mass spectrometric techniques for on-site monitoring of volatile organic compounds; A systematic database of the state of hazardous waste clean-up technologies; Dust control methods for insitu nuclear and hazardous waste handling; Winfield Lock and Dam remediation; and Socio-economic assessment of alternative environmental restoration technologies.« less

Seizing the Future: How Ohio's Career-Technical Education Programs Fuse Academic Rigor and Real-World Experiences to Prepare Students for College and Careers

ERIC Educational Resources Information Center

Guarino, Heidi; Yoder, Shaun

2015-01-01

"Seizing the Future: How Ohio's Career and Technical Education Programs Fuse Academic Rigor and Real-World Experiences to Prepare Students for College and Work," demonstrates Ohio's progress in developing strong policies for career and technical education (CTE) programs to promote rigor, including college- and career-ready graduation…

Case Study on Technical and Vocational Education in Japan. Case Studies on Technical and Vocational Education in Asia and the Pacific.

ERIC Educational Resources Information Center

Iwamoto, Muneharu

In the course of Japan's economic progress, remarkable changes have occurred in the structure of industry and employment. Workers are in extremely short supply in such occupations as mining, manufacturing and construction, services, transportation and communication, sales, and professional and technical. On the basis of recommendations of the…

25 CFR 30.104 - What is the Secretary's definition of AYP?

Code of Federal Regulations, 2011 CFR

2011-04-01

... PROGRESS Defining Adequate Yearly Progress § 30.104 What is the Secretary's definition of AYP? The... accepted by the Department of Education. The Secretary is committed to providing technical assistance to a...

25 CFR 30.104 - What is the Secretary's definition of AYP?

Code of Federal Regulations, 2010 CFR

2010-04-01

... PROGRESS Defining Adequate Yearly Progress § 30.104 What is the Secretary's definition of AYP? The... accepted by the Department of Education. The Secretary is committed to providing technical assistance to a...

FAA/NASA International Symposium on Advanced Structural Integrity Methods for Airframe Durability and Damage Tolerance

NASA Technical Reports Server (NTRS)

Harris, Charles E. (Editor)

1994-01-01

International technical experts in durability and damage tolerance of metallic airframe structures were assembled to present and discuss recent research findings and the development of advanced design and analysis methods, structural concepts, and advanced materials. The symposium focused on the dissemination of new knowledge and the peer-review of progress on the development of advanced methodologies. Papers were presented on: structural concepts for enhanced durability, damage tolerance, and maintainability; new metallic alloys and processing technology; fatigue crack initiation and small crack effects; fatigue crack growth models; fracture mechanics failure, criteria for ductile materials; structural mechanics methodology for residual strength and life prediction; development of flight load spectra for design and testing; and advanced approaches to resist corrosion and environmentally assisted fatigue.

FAA/NASA International Symposium on Advanced Structural Integrity Methods for Airframe Durability and Damage Tolerance, part 2

NASA Technical Reports Server (NTRS)

Harris, Charles E. (Editor)

1994-01-01

The international technical experts in the areas of durability and damage tolerance of metallic airframe structures were assembled to present and discuss recent research findings and the development of advanced design and analysis methods, structural concepts, and advanced materials. The principal focus of the symposium was on the dissemination of new knowledge and the peer-review of progress on the development of advanced methodologies. Papers were presented on the following topics: structural concepts for enhanced durability, damage tolerance, and maintainability; new metallic alloys and processing technology; fatigue crack initiation and small crack effects; fatigue crack growth models; fracture mechanics failure criteria for ductile materials; structural mechanics methodology for residual strength and life prediction; development of flight load spectra for design and testing; and corrosion resistance.

ANNUAL REPORT, JULY 1, 1958

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1959-02-01

This annual report of Brookhaven National Laboratory describes its program and activities for the fiscal year 1958. The progress and trends of the research program are presented along with a description of the operational, service, and administrative activities of the Laboratory. The scientific and technical details of the many research and development activities are covered more fully in scientific and technical periodicals and in the quarterly scientific progress reports and other scientiflc reports of the Laboratory. A list of all publications for July 1, 1957 to June 30, 1958, is given. Status and progress are given in fields of physics,more » accelerator development, instrumentation, applied mathematics, chemistry, nuclear engineering, biology, and medical research. (For preceding period see BNL-462.) (W.D.M.)« less

Towards a space-borne quantum gravity gradiometer: progress in laboratory demonstration

NASA Technical Reports Server (NTRS)

Yu, Nan; Kohel, James M.; Kellogg, James R.; Maleki, Lute

2005-01-01

This paper describes the working principles and technical benefits of atom-wave interferometer-based inertial sensors, and gives a progress report on the development of a quantum gravity gradiometer for space applications at JPL.

Technical Progress of the New Worlds Observer Mission

NASA Astrophysics Data System (ADS)

Lo, Amy; Noecker, C.; Cash, W.; NWO Study Team

2009-01-01

We report on the technical progress of the New Worlds Observer (NWO) mission concept. NWO is a two spacecraft mission that is capable of detecting and characterizing extra-solar, terrestrial planets and planetary systems. NWO consists of an external starshade and an UV-optical space telescope, flying in tandem. The starshade is a petal-shaped, opaque screen that creates an extremely dark shadow large enough to shade the telescope aperture from the target star. The NWO team has been addressing the top technology challenges of the concept, and report here our progress. We will present the current mission configuration best suited to address Terrestrial Planet Finding requirements, and highlight the technological breakthroughs that we have achieved this year. In particular, we will report on progress made in precision deployables for the large starshade, and the trajectory & alignment control system for NWO. We will also briefly highlight advances in understanding the starshade optical performance.

Can fisheries management make substantial progress towards further reductions in sport fish PCB concentrations?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jackson, L.J.

1995-12-31

Great Lakes managers continue to be concerned by PCB concentrations in Great Lakes sport fish. A reduction in sport fish consumption advisory levels would heighten public concern and increase pressure on managers to reduce contaminant levels in sport fish. PCB concentrations in Great Lakes sediments remain high and exchange with the water column is significant. Atmospheric inputs help maintain PCB availability in the Great Lakes. However, it is not technically feasible to control sediment and atmospheric inputs. Here the author uses a detailed age-structured simulation model of chinook salmon, alewife and rainbow smelt to examine the potential for fish managementmore » actions to make progress towards reducing PCB concentrations of sport fish consumed by humans. Chinook salmon PCB concentrations were found to be more affected by prey PCB concentrations than chinook salmon growth rates. Salmonid predators selectively attack the largest prey, but these prey are likely the oldest and most contaminated. The interaction between size selective predation by chinook salmon and their growth rates suggests that there is an ideal stocking level of sport fish that should keep the average prey fish small, and therefore have relatively low PCE concentrations, but not reduce the age structure of the alewife population to include few reproductive individuals. These results are applicable to other stocked salmonids too, (e.g., lake trout, brown trout, coho salmon, steelhead) because they also exhibit size selective predation and their recruitment is primarily by stocking.« less

Progress towards Growth and Characterization of Rare-Earth Nanoparticles using the Inverse Micelle Method

NASA Astrophysics Data System (ADS)

Romero, Dulce G.; Ho, Pei-Chun

2008-03-01

Nano-sized particles and clusters have promising electrical, chemical, and magnetic properties as compared to the bulk materials. Due to their reduced dimensionality, it makes their physical properties significantly different from the bulk material. The nano-sized materials have great potential for technical applications, such as, magnetic information storage, imaging, medical devices, and magnetic refrigeration. In this report, we will present the preliminary results on the growth and characterization of rare-earth metallic nanoparticles of Gd and Nd synthesized by the inverse micelle method [1]. These results will be compared to the bulk properties of Gd and Nd, as well as, to those exhibited by metallic nanoparticles, such as Co (by inverse micelle), and Gd (by laser evaporation cluster source), which have been found to show superparamagnetic behavior, enhanced magnetization, and self-organization [2-4]. [1] X.M. Lin, et al. Langmuir. 14, 7140 (1998). [2] D.C. Douglass, et al. Phys. Rev. B. 47, 19 (1993). [3] C. Petit, et al. Advanced Materials. 10, 259 (1998). [4] J.P. Chen, et al. Phys. Rev. B. 51, 11527 (1995).

Space life and biomedical sciences in support of the global exploration roadmap and societal development

NASA Astrophysics Data System (ADS)

Evetts, S. N.

2014-08-01

The human exploration of space is pushing the boundaries of what is technically feasible. The space industry is preparing for the New Space era, the momentum for which will emanate from the commercial human spaceflight sector, and will be buttressed by international solar system exploration endeavours. With many distinctive technical challenges to be overcome, human spaceflight requires that numerous biological and physical systems be examined under exceptional circumstances for progress to be made. To effectively tackle such an undertaking significant intra- and international coordination and collaboration is required. Space life and biomedical science research and development (R & D) will support the Global Exploration Roadmap (GER) by enabling humans to 'endure' the extreme activity that is long duration human spaceflight. In so doing the field will discover solutions to some of our most difficult human health issues, and as a consequence benefit society as a whole. This space-specific R&D will drive a significant amount of terrestrial biomedical research and as a result the international community will not only gain benefits in the form of improved healthcare in space and on Earth, but also through the growth of its science base and industry.

Amarillo National Resource Center for Plutonium. Quarterly technical progress report, May 1, 1997--July 31, 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

Progress summaries are provided from the Amarillo National Center for Plutonium. Programs include the plutonium information resource center, environment, public health, and safety, education and training, nuclear and other material studies.

Urology technical and non-technical skills development: the emerging role of simulation.

PubMed

Rashid, Prem; Gianduzzo, Troy R J

2016-04-01

To review the emerging role of technical and non-technical simulation in urological education and training. A review was conducted to examine the current role of simulation in urology training. A PUBMED search of the terms 'urology training', 'urology simulation' and 'urology education' revealed 11,504 titles. Three hundred and fifty-seven abstracts were identified as English language, peer reviewed papers pertaining to the role of simulation in urology and related topics. Key papers were used to explore themes. Some cross-referenced papers were also included. There is an ongoing need to ensure that training time is efficiently utilised while ensuring that optimal technical and non-technical skills are achieved. Changing working conditions and the need to minimise patient harm by inadvertent errors must be taken into account. Simulation models for specific technical aspects have been the mainstay of graduated step-wise low and high fidelity training. Whole scenario environments as well as non-technical aspects can be slowly incorporated into the curriculum. Doing so should also help define what have been challenging competencies to teach and evaluate. Dedicated time, resources and trainer up-skilling are important. Concurrent studies are needed to help evaluate the effectiveness of introducing step-wise simulation for technical and non-technical competencies. Simulation based learning remains the best avenue of progressing surgical education. Technical and non-technical simulation could be used in the selection process. There are good economic, logistic and safety reasons to pursue the process of ongoing development of simulation co-curricula. While the role of simulation is assured, its progress will depend on a structured program that takes advantage of what can be delivered via this medium. Overall, simulation can be developed further for urological training programs to encompass technical and non-technical skill development at all stages, including recertification. © 2015 The Authors BJU International © 2015 BJU International Published by John Wiley & Sons Ltd.

A Portfolio Analysis Tool for Measuring NASAs Aeronautics Research Progress toward Planned Strategic Outcomes

NASA Technical Reports Server (NTRS)

Tahmasebi, Farhad; Pearce, Robert

2016-01-01

Description of a tool for portfolio analysis of NASA's Aeronautics research progress toward planned community strategic Outcomes is presented. The strategic planning process for determining the community Outcomes is also briefly described. Stakeholder buy-in, partnership performance, progress of supporting Technical Challenges, and enablement forecast are used as the criteria for evaluating progress toward Outcomes. A few illustrative examples are also presented.

An approach to knowledge structuring for advanced phases of the Technical and Management Information System (TMIS)

NASA Technical Reports Server (NTRS)

Goranson, H. T.

1986-01-01

The Technical and Management Information System (TMIS) must employ on enlightened approach to its object structure, but basic issues in conceptual structuring remain to be resolved. Sirius outlines the necessary agenda and reports on progress toward solutions.

48 CFR 752.7035 - Public notices.

Code of Federal Regulations, 2011 CFR

2011-10-01

... notices. The following clause is for use when the cognizant technical office determines that the contract... to time, to announce progress and accomplishments. Press releases or other public notices should... cognizant technical officer and to USAID's Legislative and Public Affairs (LPA) as far in advance of release...

14 CFR 1260.71 - Supplements and renewals.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., continued research relevance, and progress made by the recipient. (2) To insure uninterrupted programs, the technical office should forward to the grant office a completed award package, including a funded procurement request, technical evaluation of the proposed budget, and other support documentation, at least 29...

[A technical modification of the use of Dwyer's equipment].

PubMed

Carlioz, H; Damsin, J P

1991-01-01

Dwyer's technique for correction and anterior fusion of the spine was improved by using lockers at the level of each screw. So, like with the Zielke's technic this procedure allowed a global progressive and controllable correction and a real derotation of the spine.

A systematic assessment of the state of hazardous waste clean-up technologies. Quarterly technical progress report, April 1--June 30, 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berg, M.T.; Reed, B.E.; Gabr, M.

1993-07-01

West Virginia University (WVU) and the US DOE Morgantown Energy Technology Center (METC) entered into a Cooperative Agreement on August 29, 1992 entitled ``Decontamination Systems Information and Research Programs.`` Stipulated within the Agreement is the requirement that WVU submit to METC a series of Technical Progress Report for Year 1 of the Agreement. This report reflects the progress and/or efforts performed on the following nine technical projects encompassed by the Year 1 Agreement for the period of April 1 through June 30, 1993: Systematic assessment of the state of hazardous waste clean-up technologies; site remediation technologies -- drain-enhanced soil flushingmore » (DESF) for organic contaminants removal; site remediation technologies -- in situ bioremediation of organic contaminants; excavation systems for hazardous waste sites; chemical destruction of polychlorinated biphenyls; development of organic sensors -- monolayer and multilayer self-assembled films for chemical sensors; Winfield lock and dam remediation; Assessments of Technologies for hazardous waste site remediation -- non-treatment technologies and pilot scale test facility implementation; and remediation of hazardous sites with stream reforming.« less

Progress, innovation and regulatory science in drug development: the politics of international standard-setting.

PubMed

Abraham, John; Reed, Tim

2002-06-01

This paper examines international standard-setting in the toxicology of pharmaceuticals during the 1990s, which has involved both the pharmaceutical industry and regulatory agencies in an organization known as the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). The analysis shows that the relationships between innovation, regulatory science and 'progress' may be more complex and controversial than is often assumed. An assessment of the ICH's claims about the implications of 'technical' harmonization of drug-testing standards for the maintenance of drug safety, via toxicological testing, and the delivery of therapeutic progress, via innovation, is presented. By demonstrating that there is not a technoscientific validity for these claims, it is argued that, within the ICH, a discourse of technological innovation and scientific progress has been used by regulatory agencies and prominent parts of the transnational pharmaceutical industry to legitimize the lowering and loosening of toxicological standards for drug testing. The mobilization and acceptance of this discourse are shown to be pivotal to the ICH's transformation of reductions in safety standards, which are apparently against the interests of patients and public health, into supposed therapeutic benefits derived from promises of greater access to more innovative drug products. The evidence suggests that it is highly implausible that these reductions in the standards of regulatory toxicology are consistent with therapeutic progress for patients, and highlights a worrying aspect embedded in the 'technical trajectories' of regulatory science.

7 CFR 1944.541 - Reporting requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) PROGRAM REGULATIONS (CONTINUED) HOUSING Technical and Supervisory Assistance Grants § 1944.541 Reporting... District Director to determine satisfactory progress. The District Director will work with the grantee to... five working days of receipt. (1) If the reports indicate satisfactory progress, the State Director...

The magnetohydrodynamics coal-fired flow facility

NASA Astrophysics Data System (ADS)

1995-01-01

In this quarterly technical progress report, UTSI reports on the status of a multitask contract to develop the technology for the steam bottoming portion of a MHD Steam Combined Cycle Power Plant. The report describes the facility maintenance and environmental work completed, status of completing technical reports and certain key administrative actions occurring during the quarter. With program resources at a minimum to closeout the MHD program, no further testing occurred during the quarter, but the DOE CFFF facility was maintained in a standby status with winterization, preventive maintenance and repairs accomplished as needed. Plans and preparations progressed for environmental actions needed at the site to investigate and characterize the groundwater and for removal/disposal of asbestos in the cooling tower. Work continued to progress on archiving the results of the MHD program.

The Golden Age of Technical Communication

ERIC Educational Resources Information Center

Kimball, Miles A.

2017-01-01

This article uses a historical perspective to describe the development of the profession of technical communication through three ages: Brass, Beige, and Glass. I compare this development to the growth of the academic discipline and both to the explosion of noninstitutional technical communication--the growing body of tactical technical…

Tumor heterogeneity and progression: conceptual foundations for modeling.

PubMed

Greller, L D; Tobin, F L; Poste, G

1996-01-01

A conceptual foundation for modeling tumor progression, growth, and heterogeneity is presented. The purpose of such models is to aid understanding, test ideas, formulate experiments, and to model cancer 'in machina' to address the dynamic features of tumor cell heterogeneity, progression, and growth. The descriptive capabilities of such an approach provides a consistent language for qualitatively reasoning about tumor behavior. This approach provides a schema for building conceptual models that combine three key phenomenological driving elements: growth, progression, and genetic instability. The growth element encompasses processes contributing to changes in tumor bulk and is distinct from progression per se. The progression element subsumes a broad collection of processes underlying phenotypic progression. The genetics elements represents heritable changes which potentially affect tumor character and behavior. Models, conceptual and mathematical, can be built for different tumor situations by drawing upon the interaction of these three distinct driving elements. These models can be used as tools to explore a diversity of hypotheses concerning dynamic changes in cellular populations during tumor progression, including the generation of intratumor heterogeneity. Such models can also serve to guide experimentation and to gain insight into dynamic aspects of complex tumor behavior.

GPHS-RTGs in support of the Cassini RTG Program

NASA Astrophysics Data System (ADS)

1995-04-01

The technical progress achieved during the period 26 Sep. 1994 - 2 Apr. 1995 on Contract DE-AC03-91SF-18852 Radioisotope Thermoelectric Generators and Ancillary Activities is described herein. Monthly technical activity for the period 27 Feb. - 2 Apr. 1995 is included in this progress report. The report addresses tasks, including: spacecraft integration and liaison; engineering support; safety; qualified unicouple production; ETG fabrication, assembly, and test; ground support equipment; RTG shipping and launch support; designs, reviews, and mission applications; project management, quality assurance, reliability, contract changes, CAGO acquisition (operating funds), and CAGO maintenance and repair; and CAGO acquisition (capital funds).

The Gap That Can't Go Away: The Catch-22 of Reclassification in Monitoring the Progress of English Learners

ERIC Educational Resources Information Center

Saunders, William M.; Marcelletti, David J.

2013-01-01

When English Learners (ELs) demonstrate English language proficiency, they are reclassified as Fluent English Proficient (RFEP). Subsequently they are often left out of the analysis of EL progress because they are, technically, no longer ELs. This article examines the effects of including and excluding RFEPs from the analysis of EL progress. Based…

Bone Conduction Communication: Research Progress and Directions

DTIC Science & Technology

2017-08-16

ARL-TR-8096 ● AUG 2017 US Army Research Laboratory Bone Conduction Communication: Research Progress and Directions by Maranda...this report when it is no longer needed. Do not return it to the originator. ARL-TR-8096 ● AUG 2017 US Army Research Laboratory...Bone Conduction Communication: Research Progress and Directions by Maranda McBride North Carolina Agricultural and Technical State University

25 CFR 30.123 - What is the Bureau's role in assisting Bureau-funded schools to make AYP?

Code of Federal Regulations, 2010 CFR

2010-04-01

... EDUCATION ADEQUATE YEARLY PROGRESS Failure To Make Adequate Yearly Progress § 30.123 What is the Bureau's...-funded schools to assist them in achieving AYP. This includes technical assistance and other forms of...

25 CFR 30.123 - What is the Bureau's role in assisting Bureau-funded schools to make AYP?

Code of Federal Regulations, 2011 CFR

2011-04-01

... EDUCATION ADEQUATE YEARLY PROGRESS Failure To Make Adequate Yearly Progress § 30.123 What is the Bureau's...-funded schools to assist them in achieving AYP. This includes technical assistance and other forms of...

Neurotrophin Signaling via Long-Distance Axonal Transport

NASA Astrophysics Data System (ADS)

Chowdary, Praveen D.; Che, Dung L.; Cui, Bianxiao

2012-05-01

Neurotrophins are a family of target-derived growth factors that support survival, development, and maintenance of innervating neurons. Owing to the unique architecture of neurons, neurotrophins that act locally on the axonal terminals must convey their signals across the entire axon for subsequent regulation of gene transcription in the cell nucleus. This long-distance retrograde signaling, a motor-driven process that can take hours or days, has been a subject of intense interest. In the last decade, live-cell imaging with high sensitivity has significantly increased our capability to track the transport of neurotrophins, their receptors, and subsequent signals in real time. This review summarizes recent research progress in understanding neurotrophin-receptor interactions at the axonal terminal and their transport dynamics along the axon. We emphasize high-resolution studies at the single-molecule level and also discuss recent technical advances in the field.

Microfluidics for genome-wide studies involving next generation sequencing

PubMed Central

Murphy, Travis W.; Lu, Chang

2017-01-01

Next-generation sequencing (NGS) has revolutionized how molecular biology studies are conducted. Its decreasing cost and increasing throughput permit profiling of genomic, transcriptomic, and epigenomic features for a wide range of applications. Microfluidics has been proven to be highly complementary to NGS technology with its unique capabilities for handling small volumes of samples and providing platforms for automation, integration, and multiplexing. In this article, we review recent progress on applying microfluidics to facilitate genome-wide studies. We emphasize on several technical aspects of NGS and how they benefit from coupling with microfluidic technology. We also summarize recent efforts on developing microfluidic technology for genomic, transcriptomic, and epigenomic studies, with emphasis on single cell analysis. We envision rapid growth in these directions, driven by the needs for testing scarce primary cell samples from patients in the context of precision medicine. PMID:28396707

A New Era of Minimally Invasive Surgery: Progress and Development of Major Technical Innovations in General Surgery Over the Last Decade.

PubMed

Siddaiah-Subramanya, Manjunath; Tiang, Kor Woi; Nyandowe, Masimba

2017-10-01

Minimally invasive surgery (MIS) continues to play an important role in general surgery as an alternative to traditional open surgery as well as traditional laparoscopic techniques. Since the 1980s, technological advancement and innovation have seen surgical techniques in MIS rapidly grow as it is viewed as more desirable. MIS, which includes natural orifice transluminal endoscopic surgery (NOTES) and single-incision laparoscopic surgery (SILS), is less invasive and has better cosmetic results. The technological growth and adoption of NOTES and SILS by clinicians in the last decade has however not been uniform. We look at the differences in new developments and advancement in the different techniques in the last 10 years. We also aim to explain these differences as well as the implications in general surgery for the future.

Black River Technical College, Exploring America's Communities. Progress Report.

ERIC Educational Resources Information Center

Black River Vocational-Technical School, Pocahontas, AR.

In 1996, Arkansas's Black River Technical College (BRTC) participated in the American Association of Community Colleges' Exploring America's Communities project, which worked to strengthen the teaching and learning of American history, literature, and culture at U.S. community colleges. The proposed centerpiece of BRTC's program is called the…

40 CFR 40.150 - Evaluation of applications.

Code of Federal Regulations, 2011 CFR

2011-07-01

.... Relevancy, coupled with the results of technical review, will provide the basis for funding recommendations... will be reviewed for technical merit by at least one reviewer within EPA and at least two reviewers.... Recommendations for continuation of funding will be based on progress toward the accomplishment of the goals set...

40 CFR 35.4235 - Are there specific provisions my group's contract(s) must contain?

Code of Federal Regulations, 2011 CFR

2011-07-01

... PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Technical Assistance Procuring A Technical Advisor Or Other Contractor with Tag Funds § 35.4235 Are there specific... progress reports; (3) Expenditures; and (4) Commitments indicating their relationship to established costs...

Missouri local technical assistance program at Missouri University of Science and Technology (formerly University of Missouri--Rolla) : annual progress report January-December 2007.

DOT National Transportation Integrated Search

2009-02-01

This annual report is a summary of the activities during 2007 for the Missouri Local Technical Assistance Program (Missouri LTAP), which is located at Missouri University of Science and Technology. The report highlights Missouri LTAPs performance ...

Global Issues in Career and Technical Fields: Internationalizing the Community College Curriculum.

ERIC Educational Resources Information Center

Peck, Shirley S.

1991-01-01

Presents a rationale for incorporating international content in both general education and career/technical fields, providing a status report on progress to date. Describes four modules prepared by Catonsville Community College (Maryland) instructors for inclusion in criminal justice, air transportation, automotive service, and electronics…

Technical and Vocational Education in Cameroon and Critical Avenues for Development

ERIC Educational Resources Information Center

Che, S. Megan

2007-01-01

Technical and vocational education (TVE) can influence development and economic progress for post-colonial societies. Some newly independent sub-Saharan African countries attempted curricular transformation that might produce a skilled workforce through widespread access to versions of TVE. In Cameroon, no such post-colonial curricular revolution…

Publications of the Jet Propulsion Laboratory, January through December 1974. [deep space network, Apollo project, information theory, and space exploration

NASA Technical Reports Server (NTRS)

1975-01-01

Formalized technical reporting is described and indexed, which resulted from scientific and engineering work performed, or managed, by the Jet Propulsion Laboratory. The five classes of publications included are technical reports, technical memorandums, articles from the bimonthly Deep Space Network Progress Report, special publications, and articles published in the open literature. The publications are indexed by author, subject, and publication type and number.

24 CFR 1006.430 - Corrective and remedial action.

Code of Federal Regulations, 2011 CFR

2011-04-01

... plan; (3) Made substantial progress in carrying out its program and achieving its quantifiable goals as... to submit progress schedules for completing activities or complying with the requirements of the Act... appropriate technical assistance using existing grant funds or other available resources to overcome the...

SAMS Acceleration Measurements on Mir (NASA Increment 4)

NASA Technical Reports Server (NTRS)

DeLombard, Richard

1998-01-01

During NASA Increment 4 (January to May 1997), about 5 gigabytes of acceleration data were collected by the Space Acceleration Measurements System (SAMS) onboard the Russian Space Station, Mir. The data were recorded on 28 optical disks which were returned to Earth on STS-84. During this increment, SAMS data were collected in the Priroda module to support the Mir Structural Dynamics Experiment (MiSDE), the Binary Colloidal Alloy Tests (BCAT), Angular Liquid Bridge (ALB), Candle Flames in Microgravity (CFM), Diffusion Controlled Apparatus Module (DCAM), Enhanced Dynamic Load Sensors (EDLS), Forced Flow Flame Spreading Test (FFFr), Liquid Metal Diffusion (LMD), Protein Crystal Growth in Dewar (PCG/Dewar), Queen's University Experiments in Liquid Diffusion (QUELD), and Technical Evaluation of MIM (TEM). This report points out some of the salient features of the microgravity environment to which these experiments were exposed. Also documented are mission events of interest such as the docked phase of STS-84 operations, a Progress engine bum, Soyuz vehicle docking and undocking, and Progress vehicle docking. This report presents an overview of the SAMS acceleration measurements recorded by 10 Hz and 100 Hz sensor heads. The analyses included herein complement those presented in previous summary reports prepared by the Principal Investigator Microgravity Services (PIMS) group.

Infant-Guided, Co-Regulated Feeding in the Neonatal Intensive Care Unit. Part I: Theoretical Underpinnings for Neuroprotection and Safety.

PubMed

Shaker, Catherine S

2017-04-01

The rapid progress in medical and technical innovations in the neonatal intensive care unit (NICU) has been accompanied by concern for outcomes of NICU graduates. Although advances in neonatal care have led to significant changes in survival rates of very small and extremely preterm neonates, early feeding difficulties with the transition from tube feeding to oral feeding are prominent and often persist beyond discharge to home. Progress in learning to feed in the NICU and continued growth in feeding skills after the NICU may be closely tied to fostering neuroprotection and safety. The experience of learning to feed in the NICU may predispose preterm neonates to feeding problems that persist. Neonatal feeding as an area of specialized clinical practice has grown considerably in the last decade. This article is the first in a two-part series devoted to neonatal feeding. Part 1 explores factors in NICU feeding experiences that may serve to constrain or promote feeding skill development, not only in the NICU but long after discharge to home. Part II describes approaches to intervention that support neuroprotection and safety. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Progress and Prospect: A Report Submitted to the Governing Board of the Maricopa County Community College District.

ERIC Educational Resources Information Center

Maricopa Technical Community Coll., Phoenix, AZ.

This two-part report seeks to outline the progress made to date by Maricopa Technical Community College (MTCC) through its first eight years of operation, and to recommend specific actions which might be taken in the future by the college to insure its continued progress and response to community needs in light of constraints on funding and…

Career Technical Education Pathways Initiative Annual Report

ERIC Educational Resources Information Center

California Community Colleges, Chancellor's Office, 2014

2014-01-01

California's education system--the largest in the United States--is an essential resource for ensuring strong economic growth in the state. The Career Technical Education Pathways Initiative (the Initiative) became law in 2005 with Senate Bills 70 and 1133 and provided more than $380 million over eight years to improve career technical education…

Solar Energy - It's Growth, Development, and Use

Science.gov Websites

Report, June 1978 Solar Energy and Your Home: Questions and Answers, DOE Technical Report, January 1984 Solar Air Collectors: How Much Can You Save?, DOE Technical Report, April 1985 Building Design Guidelines for Solar Energy Technologies, DOE Technical Report, January 1989 OUT Success Stories: Solar

[A review of progress in research of effect of air pollutants on fetal growth].

PubMed

Wang, W Y; Zhao, R X; Guo, H; Chen, S; Zhang, W H; Yang, S L; Wang, K; Meng, Y; Huang, J; Wei, S

2017-01-10

Slow fetal growth is a global public health concern because it might be associated with many diseases later in life. With the progress of technology to measure long-term air pollution exposure. Many epidemiological studies have evaluated the effects of maternal air pollutant exposure on fetal growth. In this paper, we summarize the research progress in this field after the analysis on the related literatures retrieved from the databases of Medline and Web of Science.

Technical Adequacy of the easyCBM Primary-Level Reading Measures (Grades K-1), 2009-2010 Version. Technical Report #1003

ERIC Educational Resources Information Center

Lai, Cheng-Fei; Nese, Joseph F. T.; Jamgochian, Elisa M.; Alonzo, Julie; Tindal, Gerald

2010-01-01

In this technical report, we provide the results of a series of studies on the technical adequacy of the early reading measures available on the easyCBM[R] assessment system. The results from the two-level hierarchical linear growth model analyses suggest that the reliability of the slope estimates for the easyCBM[R] reading measures are strong,…

Optical fiber sensors for materials and structures characterization

NASA Technical Reports Server (NTRS)

Lindner, D. K.; Claus, R. O.

1991-01-01

The final technical report on Optical Fiber Sensors for Materials and Structures Characterization, covering the period August 1990 through August 1991 is presented. Research programs in the following technical areas are described; sapphire optical fiber sensors; vibration analysis using two-mode elliptical core fibers and sensors; extrinsic Fabry-Perot interferometer development; and coatings for fluorescent-based sensor. Research progress in each of these areas was substantial, as evidenced by the technical publications which are included as appendices.

44 CFR 206.437 - State administrative plan.

Code of Federal Regulations, 2010 CFR

2010-10-01

... requests for advances of funds and reimbursement; (vii) Monitor and evaluate the progress and completion of... technical assistance as required to subgrantee(s); (xi) Comply with the administrative and audit requirements of 44 CFR parts 13 and 206; (xii) Provide quarterly progress reports to the Regional Administrator...

25 CFR 30.122 - Must the Bureau assist a school it identified for school improvement, corrective action, or...

Code of Federal Regulations, 2010 CFR

2010-04-01

..., DEPARTMENT OF THE INTERIOR EDUCATION ADEQUATE YEARLY PROGRESS Failure To Make Adequate Yearly Progress § 30... restructuring, the Bureau must provide technical or other assistance described in 20 U.S.C. 6316(b)(4) and 20 U...

44 CFR 206.437 - State administrative plan.

Code of Federal Regulations, 2011 CFR

2011-10-01

... requests for advances of funds and reimbursement; (vii) Monitor and evaluate the progress and completion of... technical assistance as required to subgrantee(s); (xi) Comply with the administrative and audit requirements of 44 CFR parts 13 and 206; (xii) Provide quarterly progress reports to the Regional Administrator...

25 CFR 30.122 - Must the Bureau assist a school it identified for school improvement, corrective action, or...

Code of Federal Regulations, 2011 CFR

2011-04-01

..., DEPARTMENT OF THE INTERIOR EDUCATION ADEQUATE YEARLY PROGRESS Failure To Make Adequate Yearly Progress § 30... restructuring, the Bureau must provide technical or other assistance described in 20 U.S.C. 6316(b)(4) and 20 U...

Assessment Program Technical Progress Report, 1997-1998.

ERIC Educational Resources Information Center

Eickmeyer, Barbara; Hill, Stephen

This Assessment Program Progress Report (APPR) records the institutional activities that have taken place at Coconino Community College (CCC) during the 1997-98 academic year. It presents models, timelines, accomplishments, and opportunities for improvement in the assessment practices at CCC. Implementation and outcomes information is included for…

Diagnostic Efficiency of easyCBM[R] Math: Oregon. Technical Report #1009

ERIC Educational Resources Information Center

Anderson, Daniel; Alonzo, Julie; Tindal, Gerald

2010-01-01

The easyCBM[R] assessment system is an online benchmark and progress monitoring assessment system designed for use within a response to intervention framework. Educators using easyCBM[R] are often interested in using the results to predict students' state test performance. In the following technical document, we report diagnostic efficiency…

Longitudinal Surveys of Australian Youth (LSAY) 2009 Cohort: Wave 2 (2010)-- Questionnaire. Technical Report 71A

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2012

2012-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the questionnaire for the LSAY 2009 cohort Wave 2 (2010) data set.

Longitudinal Surveys of Australian Youth (LSAY) 2009 Cohort: Wave 3 (2011)--Questionnaire. Technical Report 72A

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2012

2012-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the questionnaire for the LSAY 2009 cohort Wave 3 (2011) data set.

Educational Reform and the World of Work: Italy

ERIC Educational Resources Information Center

von Blumenthal, Viktor

1977-01-01

One of a four-issue series on educational reform and the world of work in Europe, this issue discusses educational planning and secondary school reform in Italy. Topics discussed include planning and research in vocational-technical education, and the relation between acquisition of specific skills and scientific and technical progress. (Author/DB)

Longitudinal Surveys of Australian Youth (LSAY) 2009 Cohort: Wave 2 (2010)--Frequency Tables. Technical Report 71B

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2012

2012-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the frequency tables for the LSAY 2009 cohort Wave 2 (2010) data set.

Higher Education in Kazakhstan and the Bologna Process

ERIC Educational Resources Information Center

Piven, G.; Pak, I.U.

2006-01-01

The constantly rising role of higher education in the twenty-first century goes hand in hand with scientific and technical progress and the global technologization of the developed countries of the world. A country's level of technical and technological development determines its economic condition, its national security, and its role in the world…

A State Response to Indian Vocational Education.

ERIC Educational Resources Information Center

McConnell, Bruce

In 1977 more than 500 Native Americans attended Wisconsin's vocational, technical and adult schools located in the state's 16 vocational-technical districts. While many problems still lack a clear identification and many new programs are needed to meet the needs of Native Americans, a great deal of progress has been made. A group of four Indians…

Analytical Chemistry Division. Annual progress report for period ending December 31, 1980

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lyon, W.S.

1981-05-01

This report is divided into: analytical methodology; mass and emission spectrometry; technical support; bio/organic analysis; nuclear and radiochemical analysis; quality assurance, safety, and tabulation of analyses; supplementary activities; and presentation of research results. Separate abstracts were prepared for the technical support, bio/organic analysis, and nuclear and radiochemical analysis. (DLC)

Scientific and Technical Information Transfer for Education (STITE). Research Report No. 2.

ERIC Educational Resources Information Center

Zunde, Pranas

STITE (Scientific and Technical Information Transfer for Education) is basically a system to interface between science information and the science learner. As such STITE acts as a link between STIC (Science and Technology Infromation Centers) and LIS (Learning Information Systems). In this second progress report the internal knowledge of STITE is…

Mathematics Technical Report: Exercise Volume. National Assessment of Educational Progress. Report No. 04-MA-20.

ERIC Educational Resources Information Center

Education Commission of the States, Denver, CO. National Assessment of Educational Progress.

Included in Chapter 1 of this report are background information on the 1972-73 mathematics assessment; details of the computational formulas used in reporting results; and explanations of the technical documentation, exercise presentation, documentation pages, scoring guides, and data tables for released and unreleased exercises. The remainder of…

Experimentation with Computer-Assisted Instruction in Technical Education. Semi-Annual Progress Report.

ERIC Educational Resources Information Center

Mitzel, Harold E.; Brandon, George L.

A series of five reports is presented which describes the activities carried out by the Pennsylvania State University group engaged in research in computer-assisted instruction (CAI) in vocational-technical education. The reports cover the period January 1968-June 1968 and deal with: 1) prior knowledge and individualized instruction; 2) numerical…

Do failures in non-technical skills contribute to fatal medical accidents in Japan? A review of the 2010–2013 national accident reports

PubMed Central

Uramatsu, Masashi; Fujisawa, Yoshikazu; Mizuno, Shinya; Souma, Takahiro; Komatsubara, Akinori; Miki, Tamotsu

2017-01-01

Objectives We sought to clarify how large a proportion of fatal medical accidents can be considered to be caused by poor non-technical skills, and to support development of a policy to reduce number of such accidents by making recommendations about possible training requirements. Design Summaries of reports of fatal medical accidents, published by the Japan Medical Safety Research Organization, were reviewed individually. Three experienced clinicians and one patient safety expert conducted the reviews to determine the cause of death. Views of the patient safety expert were given additional weight in the overall determination. Setting A total of 73 summary reports of fatal medical accidents were reviewed. These reports had been submitted by healthcare organisations across Japan to the Japan Medical Safety Research Organization between April 2010 and March 2013. Primary and secondary outcome measures The cause of death in fatal medical accidents, categorised into technical skills, non-technical skills and inevitable progress of disease were evaluated. Non-technical skills were further subdivided into situation awareness, decision making, communication, team working, leadership, managing stress and coping with fatigue. Results Overall, the cause of death was identified as non-technical skills in 34 cases (46.6%), disease progression in 33 cases (45.2%) and technical skills in two cases (5.5%). In two cases, no consensual determination could be achieved. Further categorisation of cases of non-technical skills were identified as 14 cases (41.2%) of problems with situation awareness, eight (23.5%) with team working and three (8.8%) with decision making. These three subcategories, or combinations of them, were identified as the cause of death in 33 cases (97.1%). Conclusions Poor non-technical skills were considered to be a significant cause of adverse events in nearly half of the fatal medical accidents examined. Improving non-technical skills may be effective for reducing accidents, and training in particular subcategories of non-technical skills may be especially relevant. PMID:28209605

Institutional obstacles to expansion of world food production.

PubMed

Crosson, P R

1975-05-09

It was argued that over the near-to-medium term-roughly to the mid-1980's-there is enough potential for growth in existing Green Revolution technology and in technical capacity of farmers that institutions affecting these two sources of increased food production probably will not be seriously constraining. The principal bottlenecks likely will be found among those institutions affecting farmers' incentives to innovate. There is impressive evidence that when other conditions for innovation are favorable the supply of marketing services, for both inputs and outputs, is quite elastic. This seems to include the supply of funds from rural saving and informal credit sources, although the evidence is less clear in this respect. The situation concerning price relations and availability of inputs appears mixed. If national income growth targets are achieved, then the growth in total demand for food in the LDC's should be fast enough to support incentive prices for farmers. This advantage could be lost, however, if governments adopt policies to suppress food prices to keep down the cost of living. The price of fertilizers is expected to fall from the high levels of 1974, the amount of the fall depending in good measure on the success of the LDC's in increasing fertilizer production. Historically, their efforts to expand capacity have been relatively inefficient. Moreover, many countries still lack adequate capacity to produce the HYV's and pesticides. Even with good progress in expanding domestic production of inputs, imports will continue to be an important source of supply. Maintenance of present high prices of petroleum products could be a major obstacle to financing these imports on the necessary scale because of the drain it would place on available foreign exchange. I conclude, on balance, that prices and availability of fertilizers, pesticides, and seeds could have important negative effects on farmers' incentives to adopt Green Revolution technology. Rigidities in water management institutions may be even more limiting, for reasons noted in the previous section. The role of existing land tenure institutions is not clear. The tentative conclusion, however, is that over the near-to-medium term the maintenance will not be a major obstacle to further spread of the Green Revolution. Over the longer term, it could become more seriously limiting. The reason is that continued expansion of food production will eventually require the invention and adoption of new technologies and a higher level of technical and managerial skill than most farmers in the LDC's now possess. To do this will require substantial investments in domestic research and extension institutions and in rural education. In countries where a small class of large landowners wield substantial political power, these investments may not occur on the necessary scale because the large farmers have their own means of acquiring the technology and little perceived interest in supporting the upgrading of the skills of small farmers. This review of institutional obstacles to expansion of food production in the LDC's must end on a tentative note. The review does suggest some observations about the process of institutional change, however. There is impressive evidence of strong latent potential in the private sector of the LDC's for mobilizing the resources and effort needed for agricultural progress when the private economic rewards for doing so are high. Under these circumstances, needed changes in the institutions required to mobilize the resources and direct the effort seem relatively easy to achieve. Institutional resistance is stronger in situations where influential interests perceive change as a threat or where there is no direct personal economic reward to change, as in the typical public institution. The latter point is particularly important because the performance of public institutions is critical. Development of new technology, the fundamental condition for continued longterm growth, is basically a public responsibility because the gains from adoption usually cannot be sufficiently captured by private institutions to justify their assuming the cost. Although private firms often have incentives to impart technical knowledge to farmers as a way of widening the market for their products, the broadening and strengthening of the institutional structures concerned with both the general and technical education of farmers is a public responsibility. This is true also of the development of large irrigation systems, both because of the scale of the needed investments and the potential for social conflict in water management. The lack of a well-defined mechanism that would link responses of public institutions to the large social payoffs to increased public investment in irrigation, new technology, and technical abilities of farmers may prove in the long run to be the most important single obstacle to adequate growth of food production in the LDC's.

Progress Monitoring in Middle School Mathematics: Options and Issues

ERIC Educational Resources Information Center

Foegen, Anne

2008-01-01

This study investigated the technical features of six potential progress-monitoring measures in mathematics appropriate for use at the middle school level, including two commercially available measures for sixth-grade mathematics, two measures used in previous middle school studies, and two new measures of numeracy concepts. Five hundred…

10 CFR 600.341 - Monitoring and reporting program and financial performance.

Code of Federal Regulations, 2012 CFR

2012-01-01

... will be taken to address the deviations. (2) A final technical report if the award is for research and... dates for reports. At a minimum, requirements must include: (1) Periodic progress reports (at least... follows: (i) The program portions of the reports must address progress toward achieving program...

10 CFR 600.341 - Monitoring and reporting program and financial performance.

Code of Federal Regulations, 2014 CFR

2014-01-01

... will be taken to address the deviations. (2) A final technical report if the award is for research and... dates for reports. At a minimum, requirements must include: (1) Periodic progress reports (at least... follows: (i) The program portions of the reports must address progress toward achieving program...

10 CFR 600.341 - Monitoring and reporting program and financial performance.

Code of Federal Regulations, 2013 CFR

2013-01-01

... will be taken to address the deviations. (2) A final technical report if the award is for research and... dates for reports. At a minimum, requirements must include: (1) Periodic progress reports (at least... follows: (i) The program portions of the reports must address progress toward achieving program...

10 CFR 600.341 - Monitoring and reporting program and financial performance.

Code of Federal Regulations, 2011 CFR

2011-01-01

... will be taken to address the deviations. (2) A final technical report if the award is for research and... dates for reports. At a minimum, requirements must include: (1) Periodic progress reports (at least... follows: (i) The program portions of the reports must address progress toward achieving program...

Nuclear waste management. Semiannual progress report, October 1982-March 1983

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chikalla, T.D.; Powell, J.A.

1983-06-01

This document is one of a series of technical progress reports designed to report radioactive waste management programs at the Pacific Northwest Laboratory. Accomplishments in the following programs are reported: waste stabilization; Materials Characterization Center; waste isolation; low-level waste management; remedial action; and supporting studies.

Advancing Stage 2 Research on Measures for Monitoring Kindergarten Reading Progress

ERIC Educational Resources Information Center

Clemens, Nathan H.; Soohoo, Michelle M.; Wiley, Colby P.; Hsiao, Yu-Yu; Estrella, Ivonne; Allee-Smith, Paula J.; Yoon, Myeongsun

2018-01-01

Although several measures exist for frequently monitoring early reading progress, little research has specifically investigated their technical properties when administered on a frequent basis with kindergarten students. In this study, kindergarten students (N = 137) of whom the majority was receiving supplemental intervention for reading skills…

Insulin-Like Growth Factor and Epidermal Growth Factor Signaling in Breast Cancer Cell Growth: Focus on Endocrine Resistant Disease

PubMed Central

Berdiaki, Aikaterini; Tzardi, Maria

2015-01-01

Breast cancer is the most common type of cancer for women worldwide with a lifetime risk amounting to a staggering total of 10%. It is well established that the endogenous synthesis of insulin-like growth factor (IGF) and epidermal growth factor (EGF) polypeptide growth factors are closely correlated to malignant transformation and all the steps of the breast cancer metastatic cascade. Numerous studies have demonstrated that both estrogens and growth factors stimulate the proliferation of steroid-dependent tumor cells, and that the interaction between these signaling pathways occurs at several levels. Importantly, the majority of breast cancer cases are estrogen receptor- (ER-) positive which have a more favorable prognosis and pattern of recurrence with endocrine therapy being the backbone of treatment. Unfortunately, the majority of patients progress to endocrine therapy resistant disease (acquired resistance) whereas a proportion of patients may fail to respond to initial therapy (de novo resistance). The IGF-I and EGF downstream signaling pathways are closely involved in the process of progression to therapy resistant disease. Modifications in the bioavailability of these growth factors contribute critically to disease progression. In the present review therefore, we will discuss in depth how IGF and EGF signaling participate in breast cancer pathogenesis and progression to endocrine resistant disease. PMID:26258011

Technical writing in the radiologic technology curriculum.

PubMed

Bell, R

1979-01-01

Although courses in technical writing are no longer suggested in the Curriculum Guide for Programs in Radiologic Technology, the writer believes that writing is essential to the growth of the profession and development of the professional. Emphasis is placed on some of the benefits that accrue to students who are exposed to technical writing as part of their technology curriculum.

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This report summarizes geothermal technical assistance, R&D, and technology transfer activities of the Geo-Heat Center. It describes 95 contacts with parties during this period related to technical assistance with goethermal direct heat projects. Areas dealt with include geothermal heat pumps, space heating, greenhouses, aquaculture, equipment, economics, and resources. Research activities are summarized on geothermal district heating system cost evaluation and silica waste utilization project. Outreach activities include publication of a geothermal direct use Bulletin, dissemination of information, goethermal library, technical papers and seminars, and progress monitor reports on geothermal resources and utilization.

Sensitivity analysis of the add-on price estimate for the silicon web growth process

NASA Technical Reports Server (NTRS)

Mokashi, A. R.

1981-01-01

The web growth process, a silicon-sheet technology option, developed for the flat plate solar array (FSA) project, was examined. Base case data for the technical and cost parameters for the technical and commercial readiness phase of the FSA project are projected. The process add on price, using the base case data for cost parameters such as equipment, space, direct labor, materials and utilities, and the production parameters such as growth rate and run length, using a computer program developed specifically to do the sensitivity analysis with improved price estimation are analyzed. Silicon price, sheet thickness and cell efficiency are also discussed.

The evolution of endovascular electroencephalography: historical perspective and future applications.

PubMed

Sefcik, Roberta K; Opie, Nicholas L; John, Sam E; Kellner, Christopher P; Mocco, J; Oxley, Thomas J

2016-05-01

Current standard practice requires an invasive approach to the recording of electroencephalography (EEG) for epilepsy surgery, deep brain stimulation (DBS), and brain-machine interfaces (BMIs). The development of endovascular techniques offers a minimally invasive route to recording EEG from deep brain structures. This historical perspective aims to describe the technical progress in endovascular EEG by reviewing the first endovascular recordings made using a wire electrode, which was followed by the development of nanowire and catheter recordings and, finally, the most recent progress in stent-electrode recordings. The technical progress in device technology over time and the development of the ability to record chronic intravenous EEG from electrode arrays is described. Future applications for the use of endovascular EEG in the preoperative and operative management of epilepsy surgery are then discussed, followed by the possibility of the technique's future application in minimally invasive operative approaches to DBS and BMI.

Progress and profit through microtechnologies: commercial applications of MEMS/MOEMS

NASA Astrophysics Data System (ADS)

Ehrfeld, Wolfgang; Ehrfeld, Ursula

2001-09-01

Micro technology deals with miniaturization and integration in all areas of technology outside of microelectronics like micro mechanics, micro optics, micro acoustics, micro fluid technology, micro reaction technology and further disciplines which are focused on technical components and systems with characteristic dimensions in the micrometer range. Within a period of about ten years a multi-billion dollar market has been set up with many products for daily life. The growth rate of the market of micro technology will remain on a high level for the years to come. Mega trends resulting from fundamental human wishes for health, information, mobility and sustainable development are creating a further growing basis for micro technical products. A broad spectrum of production processes and materials has been developed to meet the requirements of a strongly diversified range of applications. For the development of new components and systems the importance of software tools for simulation of functional properties, production processes and comprehensive optimization is growing rapidly. Micro devices are meanwhile used extensively in information, automotive, and medical technologies. In addition, micro technology is generating a completely novel basis for chemical engineering, life sciences, industrial automation and optical communication, to mention only a few disciplines where future innovation will be dominated by miniaturization.

THE DEVELOPMENT OF ACHIEVEMENT MEASURES FOR TRADE AND TECHNICAL EDUCATION. PROGRESS REPORT NUMBER THREE.

ERIC Educational Resources Information Center

BALDWIN, THOMAS S.

DURING THIS PERIOD FROM SEPTEMBER 1 THROUGH NOVEMBER 30, 1966, 35 FIELD CONSULTANTS COMPLETED ANALYSIS OF THEIR INDIVIDUAL TRADE AND TECHNICAL CURRICULUMS. THESE ANALYSES WERE DEVELOPED INTO AN OUTLINE TO SERVE AS A GUIDE FOR DEVELOPING ACHIEVEMENT TESTS. THE FINAL OUTLINE WAS DIVIDED INTO AS MANY DIFFERENT AREAS AS THE CONSULTANTS FELT NECESSARY…

25 CFR 547.7 - What are the minimum technical hardware standards applicable to Class II gaming systems?

Code of Federal Regulations, 2011 CFR

2011-04-01

... OF CLASS II GAMES § 547.7 What are the minimum technical hardware standards applicable to Class II... the game, and are specially manufactured or proprietary and not off-the-shelf, shall display a unique... outcome or integrity of any game, progressive award, financial instrument, cashless transaction, voucher...

25 CFR 547.7 - What are the minimum technical hardware standards applicable to Class II gaming systems?

Code of Federal Regulations, 2012 CFR

2012-04-01

... OF CLASS II GAMES § 547.7 What are the minimum technical hardware standards applicable to Class II... the game, and are specially manufactured or proprietary and not off-the-shelf, shall display a unique... outcome or integrity of any game, progressive award, financial instrument, cashless transaction, voucher...

25 CFR 547.7 - What are the minimum technical hardware standards applicable to Class II gaming systems?

Code of Federal Regulations, 2010 CFR

2010-04-01

... OF CLASS II GAMES § 547.7 What are the minimum technical hardware standards applicable to Class II... the game, and are specially manufactured or proprietary and not off-the-shelf, shall display a unique... outcome or integrity of any game, progressive award, financial instrument, cashless transaction, voucher...

Diagnostic Efficiency of easyCBM[R] Math: Washington State. Technical Report #1008

ERIC Educational Resources Information Center

Anderson, Daniel; Alonzo, Julie; Tindal, Gerald

2010-01-01

easyCBM[R] is an online benchmark and progress monitoring assessment system designed for use within a response to intervention framework. Educators using easyCBM[R] are often interested in using the results to predict students' state test performance. In the following technical document, we report diagnostic efficiency statistics using a sample…

U.S. TIMSS and PIRLS 2011 Technical Report and User's Guide. NCES 2013-046

ERIC Educational Resources Information Center

Kastberg, David; Roey, Stephen; Ferraro, David; Lemanski, Nita; Erberber, Ebru

2013-01-01

The "U.S. TIMSS and PIRLS 2011 Technical Report and User's Guide" provides an overview of the design and implementation of the Trends in International Mathematics and Science Study (TIMSS) 2011 and the Progress in International Reading Literacy Study (PIRLS) 2011 in the United States and the nine participating benchmarking states:…

Longitudinal Surveys of Australian Youth (LSAY) 1998 Cohort: Wave 12 (2009)--Questionnaire. Technical Report 58A

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2010

2010-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the questionnaire for the LSAY 1998 cohort Wave 12 (2009) data set. [For the accompanying frequency tables, "Longitudinal Surveys…

The Development of the easyCBM CCSS Reading Assessments: Grade 3. Technical Report #1221

ERIC Educational Resources Information Center

Alonzo, Julie; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we document the development and piloting of easyCBM reading measures aligned to the Common Core State Standards, designed for use in screening students at risk for reading difficulty and monitoring their progress as they develop reading skills. The measures, which assess students' ability to respond to…

Developing Technical Writing Skills in the Physical Chemistry Laboratory: A Progressive Approach Employing Peer Review

ERIC Educational Resources Information Center

Gragson, Derek E.; Hagen, John P.

2010-01-01

Writing formal "journal-style" lab reports is often one of the requirements chemistry and biochemistry students encounter in the physical chemistry laboratory. Helping students improve their technical writing skills is the primary reason this type of writing is a requirement in the physical chemistry laboratory. Developing these skills is an…

Quality and Quality Assurance in Technical and Vocational Education and Training. Thematic Studies

ERIC Educational Resources Information Center

Seyfried, Erwin

2008-01-01

In many countries in both the Mediterranean region and the European Union (EU), interest in the quality of, and improvements to, technical and vocational education and training (TVET) systems has increased progressively in recent years. The main reason underlying this interest is a growing awareness of the key role played by education and training…

The Development of CBM Vocabulary Measures: Grade 4. Technical Report #1211

ERIC Educational Resources Information Center

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 7. Technical Report #1214

ERIC Educational Resources Information Center

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 5. Technical Report #1212

ERIC Educational Resources Information Center

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 8. Technical Report #1215

ERIC Educational Resources Information Center

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 2. Technical Report #1209

ERIC Educational Resources Information Center

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 3. Technical Report #1210

ERIC Educational Resources Information Center

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 6. Technical Report # 1213

ERIC Educational Resources Information Center

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

Application of Communications Satellites to Educational Development. Final Technical Report, September 1, 1969-August 31, 1975.

ERIC Educational Resources Information Center

Morgan, Robert P.

Research is summarized in a brief final report built around a four-section bibliography. The first section lists periodic progress reports and articles which provide an overview of the program, including articles which pertain primarily to educational rather than technical aspects of satellite utilization. Theses carried out in the fields of…

Technical efficiency and productivity of Chinese county hospitals: an exploratory study in Henan province, China.

PubMed

Cheng, Zhaohui; Tao, Hongbing; Cai, Miao; Lin, Haifeng; Lin, Xiaojun; Shu, Qin; Zhang, Ru-Ning

2015-09-09

Chinese county hospitals have been excessively enlarging their scale during the healthcare reform since 2009. The purpose of this paper is to examine the technical efficiency and productivity of county hospitals during the reform process, and to determine whether, and how, efficiency is affected by various factors. 114 sample county hospitals were selected from Henan province, China, from 2010 to 2012. Data envelopment analysis was employed to estimate the technical and scale efficiency of sample hospitals. The Malmquist index was used to calculate productivity changes over time. Tobit regression was used to regress against 4 environmental factors and 5 institutional factors that affected the technical efficiency. (1) 112 (98.2%), 112 (98.2%) and 104 (91.2%) of the 114 sample hospitals ran inefficiently in 2010, 2011 and 2012, with average technical efficiency of 0.697, 0.748 and 0.790, respectively. (2) On average, during 2010-2012, productivity of sample county hospitals increased by 7.8%, which was produced by the progress in technical efficiency changes and technological changes of 0.9% and 6.8%, respectively. (3) Tobit regression analysis indicated that government subsidy, hospital size with above 618 beds and average length of stay assumed a negative sign with technical efficiency; bed occupancy rate, ratio of beds to nurses and ratio of nurses to physicians assumed a positive sign with technical efficiency. There was considerable space for technical efficiency improvement in Henan county hospitals. During 2010-2012, sample hospitals experienced productivity progress; however, the adverse change in pure technical efficiency should be emphasised. Moreover, according to the Tobit results, policy interventions that strictly supervise hospital bed scale, shorten the average length of stay and coordinate the proportion among physicians, nurses and beds, would benefit hospital efficiency. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Technical efficiency and productivity of Chinese county hospitals: an exploratory study in Henan province, China

PubMed Central

Cheng, Zhaohui; Tao, Hongbing; Cai, Miao; Lin, Haifeng; Lin, Xiaojun; Shu, Qin; Zhang, Ru-ning

2015-01-01

Objectives Chinese county hospitals have been excessively enlarging their scale during the healthcare reform since 2009. The purpose of this paper is to examine the technical efficiency and productivity of county hospitals during the reform process, and to determine whether, and how, efficiency is affected by various factors. Setting and participants 114 sample county hospitals were selected from Henan province, China, from 2010 to 2012. Outcome measures Data envelopment analysis was employed to estimate the technical and scale efficiency of sample hospitals. The Malmquist index was used to calculate productivity changes over time. Tobit regression was used to regress against 4 environmental factors and 5 institutional factors that affected the technical efficiency. Results (1) 112 (98.2%), 112 (98.2%) and 104 (91.2%) of the 114 sample hospitals ran inefficiently in 2010, 2011 and 2012, with average technical efficiency of 0.697, 0.748 and 0.790, respectively. (2) On average, during 2010–2012, productivity of sample county hospitals increased by 7.8%, which was produced by the progress in technical efficiency changes and technological changes of 0.9% and 6.8%, respectively. (3) Tobit regression analysis indicated that government subsidy, hospital size with above 618 beds and average length of stay assumed a negative sign with technical efficiency; bed occupancy rate, ratio of beds to nurses and ratio of nurses to physicians assumed a positive sign with technical efficiency. Conclusions There was considerable space for technical efficiency improvement in Henan county hospitals. During 2010–2012, sample hospitals experienced productivity progress; however, the adverse change in pure technical efficiency should be emphasised. Moreover, according to the Tobit results, policy interventions that strictly supervise hospital bed scale, shorten the average length of stay and coordinate the proportion among physicians, nurses and beds, would benefit hospital efficiency. PMID:26353864

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gauglitz, Phillip A.; Bontha, Jagannadha R.; Daniel, Richard C.

The Hanford Waste Treatment and Immobilization Plant (WTP) is currently being designed and constructed to pretreat and vitrify a large portion of the waste in the 177 underground waste storage tanks at the Hanford Site. A number of technical issues related to the design of the pretreatment facility (PTF) of the WTP have been identified. These issues must be resolved prior to the U.S. Department of Energy (DOE) Office of River Protection (ORP) reaching a decision to proceed with engineering, procurement, and construction activities for the PTF. One of the issues is Technical Issue T1 - Hydrogen Gas Release frommore » Vessels (hereafter referred to as T1). The focus of T1 is identifying controls for hydrogen release and completing any testing required to close the technical issue. In advance of selecting specific controls for hydrogen gas safety, a number of preliminary technical studies were initiated to support anticipated future testing and to improve the understanding of hydrogen gas generation, retention, and release within PTF vessels. These activities supported the development of a plan defining an overall strategy and approach for addressing T1 and achieving technical endpoints identified for T1. Preliminary studies also supported the development of a test plan for conducting testing and analysis to support closing T1. Both of these plans were developed in advance of selecting specific controls, and in the course of working on T1 it was decided that the testing and analysis identified in the test plan were not immediately needed. However, planning activities and preliminary studies led to significant technical progress in a number of areas. This report summarizes the progress to date from the preliminary technical studies. The technical results in this report should not be used for WTP design or safety and hazards analyses and technical results are marked with the following statement: “Preliminary Technical Results for Planning – Not to be used for WTP Design or Safety Analyses.”« less

Thermal Diffusivity for III-VI Semiconductor Melts at Different Temperatures

NASA Technical Reports Server (NTRS)

Ban, H.; Li, C.; Lin, B.; Emoto, K.; Scripa, R. N.; Su, C.-H.; Lehoczky, S. L.

2004-01-01

The change of the thermal properties of semiconductor melts reflects the structural changes inside the melts, and a fundamental understanding of this structural transformation is essential for high quality semiconductor crystal growth process. This paper focused on the technical development and the measurement of thermal properties of III-VI semiconductor melts at high temperatures. Our previous work has improved the laser flash method for the specialized quartz sample cell. In this paper, we reported the results of our recent progress in further improvements of the measurement system by minimizing the free convection of the melt, adding a front IR detector, and placing the sample cell in a vacuum environment. The results for tellurium and selenium based compounds, some of which have never been reported in the literature, were obtained at different temperatures as a function of time. The data were compared with other measured thermophysical properties to shed light on the structural transformations of the melt.

Advanced thermally stable jet fuels. Technical progress report, January 1995--March 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schobert, H.H.; Eser, S.; Song, C.

Quantitative structure-property relationships have been applied to study the thermal stability of pure hydrocarbons typical of jet fuel components. A simple method of chemical structure description in terms of Benson groups was tested in searching for structure-property relationships for the hydrocarbons tested experimentally in this program. Molecular connectivity as a structure-based approach to chemical structure-property relationship analysis was also tested. Further development of both the experimental data base and computational methods will be necessary. Thermal decomposition studies, using glass tube reactors, were extended to two additional model compounds: n-decane and n-dodecane. Efforts on refining the deposit growth measurement and characterizationmore » of suspended matter in stressed fuels have lead to improvements in the analysis of stressed fuels. Catalytic hydrogenation and dehydrogenation studies utilizing a molybdenum sulfide catalyst are also described.« less

Computational fluid dynamics: Transition to design applications

NASA Technical Reports Server (NTRS)

Bradley, R. G.; Bhateley, I. C.; Howell, G. A.

1987-01-01

The development of aerospace vehicles, over the years, was an evolutionary process in which engineering progress in the aerospace community was based, generally, on prior experience and data bases obtained through wind tunnel and flight testing. Advances in the fundamental understanding of flow physics, wind tunnel and flight test capability, and mathematical insights into the governing flow equations were translated into improved air vehicle design. The modern day field of Computational Fluid Dynamics (CFD) is a continuation of the growth in analytical capability and the digital mathematics needed to solve the more rigorous form of the flow equations. Some of the technical and managerial challenges that result from rapidly developing CFD capabilites, some of the steps being taken by the Fort Worth Division of General Dynamics to meet these challenges, and some of the specific areas of application for high performance air vehicles are presented.

Cells producing their own nemesis: understanding methylglyoxal metabolism.

PubMed

Chakraborty, Sangeeta; Karmakar, Kapudeep; Chakravortty, Dipshikha

2014-10-01

Methylglyoxal, which is technically known as 2-oxopropanal or pyruvaldehyde, shows typical reactions of carbonyl compounds as it has both an aldehyde and a ketone functional group. It is an extremely cytotoxic physiological metabolite, which is generated by both enzymatic and nonenzymatic reactions. The deleterious nature of the compound is due to its ability to glycate and crosslink macromolecules like protein and DNA, respectively. However, despite having toxic effects on cellular processes, methylglyoxal retains its efficacy as an anticancer drug. Indeed, methylglyoxal is one of the well-known anticancer therapeutic agents used in the treatment. Several studies on methylglyoxal biology revolve around the manifestations of its inhibitory effects and toxicity in microbial growth and diabetic complications, respectively. Here, we have revisited the chronology of methylglyoxal research with emphasis on metabolism of methylglyoxal and implications of methylglyoxal production or detoxification on bacterial pathogenesis and disease progression. © 2014 International Union of Biochemistry and Molecular Biology.

Silicon on Ceramic Process: Silicon Sheet Growth and Device Development for the Large-area Silicon Sheet and Cell Development Tasks of the Low-cost Solar Array Project

NASA Technical Reports Server (NTRS)

Chapman, P. W.; Zook, J. D.; Heaps, J. D.; Pickering, C.; Grung, B. L.; Koepke, B.; Schuldt, S. B.

1979-01-01

The technical and economic feasibility of producing solar cell quality sheet silicon was investigated. It was hoped this could be done by coating one surface of carbonized ceramic substrates with a thin layer of large-grain polycrystalline silicon from the melt. Work was directed towards the solution of unique cell processing/design problems encountered with the silicon-ceramic (SOC) material due to its intimate contact with the ceramic substrate. Significant progress was demonstrated in the following areas; (1) the continuous coater succeeded in producing small-area coatings exhibiting unidirectional solidification and substatial grain size; (2) dip coater succeeded in producing thick (more than 500 micron) dendritic layers at coating speeds of 0.2-0.3 cm/sec; and (3) a standard for producing total area SOC solar cells using slotted ceramic substrates was developed.

AQUAHOL: a developmental project. Technical progress report, November 1980-July 1981

DOE Office of Scientific and Technical Information (OSTI.GOV)

Woodbridge, D.D.; Doering, W.C.

1981-07-01

During the period from November 1980 through July 1981, the potential of commercially growing cattails for use in making alcohol was studied by the Palm Beach Junior College and Sub-Grantee, Lantana Boatyard Inc. and a contractor, Gressinger and Sons Inc. The study involved the conversion of wild cattail rhizomes, roots, and nodal tissues to alcohol, the design of a basic harvesting mechanism, and the planting and growth of cattails on a commercial size acreage. Results of the study show that, alcohol can be made from cattails in greater quantities per acre than other considered crops; one of the factors withmore » using cattails as a commercial crop is the requirement for the development of specialized harvesting equipment; cattails will provide an excellent crop for marginal farm land that is often flooded or swampy and too wet for other crops. 71 refs., 46 figs., 1 tab.« less

Understanding of Leaf Development-the Science of Complexity.

PubMed

Malinowski, Robert

2013-06-25

The leaf is the major organ involved in light perception and conversion of solar energy into organic carbon. In order to adapt to different natural habitats, plants have developed a variety of leaf forms, ranging from simple to compound, with various forms of dissection. Due to the enormous cellular complexity of leaves, understanding the mechanisms regulating development of these organs is difficult. In recent years there has been a dramatic increase in the use of technically advanced imaging techniques and computational modeling in studies of leaf development. Additionally, molecular tools for manipulation of morphogenesis were successfully used for in planta verification of developmental models. Results of these interdisciplinary studies show that global growth patterns influencing final leaf form are generated by cooperative action of genetic, biochemical, and biomechanical inputs. This review summarizes recent progress in integrative studies on leaf development and illustrates how intrinsic features of leaves (including their cellular complexity) influence the choice of experimental approach.

Understanding of Leaf Development—the Science of Complexity

PubMed Central

Malinowski, Robert

2013-01-01

The leaf is the major organ involved in light perception and conversion of solar energy into organic carbon. In order to adapt to different natural habitats, plants have developed a variety of leaf forms, ranging from simple to compound, with various forms of dissection. Due to the enormous cellular complexity of leaves, understanding the mechanisms regulating development of these organs is difficult. In recent years there has been a dramatic increase in the use of technically advanced imaging techniques and computational modeling in studies of leaf development. Additionally, molecular tools for manipulation of morphogenesis were successfully used for in planta verification of developmental models. Results of these interdisciplinary studies show that global growth patterns influencing final leaf form are generated by cooperative action of genetic, biochemical, and biomechanical inputs. This review summarizes recent progress in integrative studies on leaf development and illustrates how intrinsic features of leaves (including their cellular complexity) influence the choice of experimental approach. PMID:27137383

India's pulp and paper industry: Productivity and energy efficiency

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schumacher, Katja

1999-07-01

Historical estimates of productivity growth in India's pulp and paper sector vary from indicating an improvement to a decline in the sector's productivity. The variance may be traced to the time period of study, source of data for analysis, and type of indices and econometric specifications used for reporting productivity growth. The authors derive both statistical and econometric estimates of productivity growth for this sector. Their results show that productivity declined over the observed period from 1973-74 to 1993-94 by 1.1% p.a. Using a translog specification the econometric analysis reveals that technical progress in India's pulp and paper sector hasmore » been biased towards the use of energy and material, while it has been capital and labor saving. The decline in productivity was caused largely by the protection afforded by high tariffs on imported paper products and other policies, which allowed inefficient, small plants to enter the market and flourish. Will these trends continue into the future, particularly where energy use is concerned? The authors examine the current changes in structure and energy efficiency undergoing in the sector. Their analysis shows that with liberalization of the sector, and tighter environmental controls, the industry is moving towards higher efficiency and productivity. However, the analysis also shows that because these improvements are being hampered by significant financial and other barriers the industry might have a long way to go.« less

Progress Monitoring with Computer Adaptive Assessments: The Impact of Data Collection Schedule on Growth Estimates

ERIC Educational Resources Information Center

Nelson, Peter M.; Van Norman, Ethan R.; Klingbeil, Dave A.; Parker, David C.

2017-01-01

Although extensive research exists on the use of curriculum-based measures for progress monitoring, little is known about using computer adaptive tests (CATs) for progress-monitoring purposes. The purpose of this study was to evaluate the impact of the frequency of data collection on individual and group growth estimates using a CAT. Data were…

Some Thoughts on "Using Learning Progressions to Design Vertical Scales That Support Coherent Inferences about Student Growth"

ERIC Educational Resources Information Center

Kingston, Neal M.; Broaddus, Angela; Lao, Hongling

2015-01-01

Briggs and Peck (2015) have written a thought-provoking article on the use of learning progressions in the design of vertical scales that support inferences about student growth. Organized learning models, including learning trajectories, learning progressions, and learning maps have been the subject of research for many years, but more recently…

Testing the Importance of Individual Growth Curves in Predicting Performance on a High-Stakes Reading Comprehension Test in Florida. REL 2014-006

ERIC Educational Resources Information Center

Petscher, Yaacov; Kershaw, Sarah; Koon, Sharon; Foorman, Barbara R.

2014-01-01

Districts and schools use progress monitoring to assess student progress, to identify students who fail to respond to intervention, and to further adapt instruction to student needs. Researchers and practitioners often use progress monitoring data to estimate student achievement growth (slope) and evaluate changes in performance over time for…

Orthotopic tumorgrafts in nude mice: A new method to study human prostate cancer.

PubMed

Saar, Matthias; Körbel, Christina; Linxweiler, Johannes; Jung, Volker; Kamradt, Jörn; Hasenfus, Andrea; Stöckle, Michael; Unteregger, Gerhard; Menger, Michael D

2015-10-01

In vivo model systems in prostate cancer research that authentically reproduce tumor growth are still sparse. While orthotopic implantation is technically difficult, particularly in the mouse, most models favor subcutaneous tumor growth. This however provides little information about natural tumor growth behavior and tumor stroma interaction. Furthermore, established prostate cancer cell lines grown as in vivo xenografts are not able to reflect the variety of tumor specific growth patterns and growth behavior in men. Primary cell cultures are difficult to handle and an induction of orthotopic tumors has not been successful yet. Therefore, a tumorgraft model using tumor tissue from prostatectomy specimens was developed. Balb/c nude mice were used to graft fresh prostate tumor tissue by renal subcapsular and orthotopic implantation. Testosterone propionate was supplemented. Animals were tracked by means of 30 MHz ultrasound to monitor tumor engraftment and growth. Autopsy, histology, PSA measurements as well as immunostaining and PCR for human tissue were performed to confirm orthotopic tumor growth. Renal subcapsular engraftment was seen in 2 of 3 mice. Orthotopic engraftment was observed in 7 of 11 animals (63.6%) with an overall engraftment of 5 out of 9 patient specimens (55.6%). Ultrasound confirmed the tumor growth over time. Of interest, the tumorgrafts not only retained essential features of the parental tumors, but also stained positive for tumor specific markers such as AR, PSA, and AMACR. Tumor positive animals showed highly elevated serum PSA levels with confirmation of a human specific PCR sequence and a human endothelial cell lining in the tumor vessels. Standardized implantation of fresh tumor tissue in nude mice prostates generates tumorgrafts with histological properties of organ-confined prostate cancer. These tumorgrafts display a new approach for an optimized in vivo model of prostate cancer and will allow further investigations on specific pathways of tumor initiation and progression as well as therapeutic response. © 2015 Wiley Periodicals, Inc.

The New Institutionalism: Mismatches with Private Higher Education's Global Growth. PROPHE Working Paper Series. WP No. 3

ERIC Educational Resources Information Center

Levy, Daniel C.

2004-01-01

Spectacular contemporary growth in private higher education challenges the "new institutionalism" and its emphasis on "isomorphism." The growth brings great inter-organizational distinctiveness and is linked to technically rational competition. Findings about this growth and distinctiveness lead us to re-assess and revise…

Accessing key steps of human tumor progression in vivo by using an avian embryo model

NASA Astrophysics Data System (ADS)

Hagedorn, Martin; Javerzat, Sophie; Gilges, Delphine; Meyre, Aurélie; de Lafarge, Benjamin; Eichmann, Anne; Bikfalvi, Andreas

2005-02-01

Experimental in vivo tumor models are essential for comprehending the dynamic process of human cancer progression, identifying therapeutic targets, and evaluating antitumor drugs. However, current rodent models are limited by high costs, long experimental duration, variability, restricted accessibility to the tumor, and major ethical concerns. To avoid these shortcomings, we investigated whether tumor growth on the chick chorio-allantoic membrane after human glioblastoma cell grafting would replicate characteristics of the human disease. Avascular tumors consistently formed within 2 days, then progressed through vascular endothelial growth factor receptor 2-dependent angiogenesis, associated with hemorrhage, necrosis, and peritumoral edema. Blocking of vascular endothelial growth factor receptor 2 and platelet-derived growth factor receptor signaling pathways by using small-molecule receptor tyrosine kinase inhibitors abrogated tumor development. Gene regulation during the angiogenic switch was analyzed by oligonucleotide microarrays. Defined sample selection for gene profiling permitted identification of regulated genes whose functions are associated mainly with tumor vascularization and growth. Furthermore, expression of known tumor progression genes identified in the screen (IL-6 and cysteine-rich angiogenic inducer 61) as well as potential regulators (lumican and F-box-only 6) follow similar patterns in patient glioma. The model reliably simulates key features of human glioma growth in a few days and thus could considerably increase the speed and efficacy of research on human tumor progression and preclinical drug screening. angiogenesis | animal model alternatives | glioblastoma

Utah's 1988-93 Vocational-Technical Education Master Plan: A Powerful Resource for Human and Economic Development.

ERIC Educational Resources Information Center

Utah State Board of Higher Education, Salt Lake City.

For Utah residents to remain in the forefront or even stay competitive economically, the state's work force must acquire the knowledge and skills that match or exceed those of their most technically advanced competitors. A powerful engine for economic growth is a high-quality system of vocational-technical education. The majority of Utah public…

Technical Adequacy of Curriculum-Based Measures of Vocabulary Growth for Preschool English Language Learners

ERIC Educational Resources Information Center

VanTol, Kathleen M.

2009-01-01

The purpose of this study was to design and establish the technical adequacy of curriculum-based measures (CBMs) of vocabulary acquisition for use with preschool children. This study sought to establish the technical adequacy of two tools that can be used for measuring benchmarks of vocabulary acquisition for both native English speakers and for…

Technical Adequacy of the easyCBM[R] Mathematics Measures: Grades 3-8, 2009-2010 Version. Technical Report #1007

ERIC Educational Resources Information Center

Nese, Joseph F. T.; Lai, Cheng-Fei; Anderson, Daniel; Jamgochian, Elisa M.; Kamata, Akihito; Saez, Leilani; Park, Bitnara J.; Alonzo, Julie; Tindal, Gerald

2010-01-01

In this technical report, data are presented on the practical utility, reliability, and validity of the easyCBM[R] mathematics (2009-2010 version) measures for students in grades 3-8 within four districts in two states. Analyses include: minimum acceptable within-year growth; minimum acceptable year-end benchmark performance; internal and…

Employers' Perception of Graduates with Entry-Level Technical Skills from Construction Industry Programs in Ghana and Nigeria

ERIC Educational Resources Information Center

Acheampong, Philip

2013-01-01

The purpose of this comparative study was to identify the technical skills and abilities needed by prospective employees of construction industries in Ghana and Nigeria. Potential employees were defined here as recent graduates of construction industry programs with entry-level technical skills. The continuous growth in and expansion of these two…

Thin EFG octagons

NASA Astrophysics Data System (ADS)

Kalejs, J. P.

1994-03-01

This report describes work to advance the manufacturing line capabilities in crystal growth and laser cutting of Mobil Solar's unique edge-defined film-fed growth (EFG) octagon technology and to reduce the manufacturing costs of 10 cm x 10 cm polycrystalline silicon EFG wafers. The report summarizes the significant technical improvements in EFG technology achieved in the first 6 months of the PVMaT Phase 2 and the success in meeting program milestones. Technical results are reported for each of the three main pregrain areas: Task 5 -- Thin octagon growth (crystal growth) to reduce the thickness of the octagon to 200 microns; Task 6 -- Laser cutting-to improve the laser cutting process so as to produce wafers with decreased laser cutting damage at increased wafer throughput rates; and Task 7 -- Process control and product specification to implement advanced strategies in crystal growth process control and productivity designed to increase wafer yields.

Automotive Stirling engine development program

NASA Technical Reports Server (NTRS)

Ernst, W.; Richey, A.; Farrell, R.; Riecke, G.; Smith, G.; Howarth, R.; Cronin, M.; Simetkosky, M.; Meacher, J.

1986-01-01

This is the ninth Semiannual Technical Progress Report prepared under the Automotive Stirling Engine Development Program. It covers the twenty-eighth and twenty-ninth quarters of activity after award of the contract. Quarterly Technical Progress Reports related program activities from the first through the thirteenth quarters; thereafter, reporting was changed to a Semiannual format. This report summarizes the study of higher-power kinematic Stirling engines for transportation use, development testing of Mod I Stirling engines, and component development activities. Component development testing included successful conical fuel nozzle testing and functional checkout of Mod II controls and auxiliaries on Mod I engine test beds. Overall program philosophy is outlined and data and test results are presented.

Publications of the Jet Propulsion Laboratory, 1981

NASA Technical Reports Server (NTRS)

1982-01-01

Over 500 externally distributed technical reports released during 1981 that resulted from scientific and engineering work performed, or managed by Jet Propulsion Laboratory are listed by primary author. Of the total number of entries, 311 are from the bimonthly Deep Space Network Progress Report, and its successor, the Telecommunications and Data Acquisition Progress Report.

40 CFR 35.4170 - What kinds of reporting does EPA require?

Code of Federal Regulations, 2011 CFR

2011-07-01

... OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Technical Assistance Managing Your Tag... period which ends June 30 and December 31 of each year. (b) [Reserved] (c) Progress Report Full description in chart or narrative format of the progress your group made in relation to your approved schedule...

77 FR 75441 - Healthy Home and Lead Hazard Control Grant Programs Data Collection; Progress Reporting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-20

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5603-N-93] Healthy Home and Lead Hazard... collection is designed to provide HUD timely information on progress of Healthy Homes Demonstration Program, Healthy Homes Technical Studies Program, Lead Base paint Hazard Control program, Lead Hazard Reduction...

Measuring Student Progress in the Classroom: A Guide to Testing and Evaluating Progress of Students with Disabilities.

ERIC Educational Resources Information Center

Hartman, Rhona C.; Redden, Martha Ross

This fact sheet provides guidelines on adapting testing situations for disabled postsecondary students. Discussed in the first section are considerations in determining when testing adaptations are needed including disability verification procedures, policy consistency, and maintenance of academic and technical standards. Facts about disabilities…

Progress in the First Five Years: An Evaluation of Achieving the Dream Colleges in Washington State

ERIC Educational Resources Information Center

Jenkins, Davis; Wachen, John; Kerrigan, Monica Reid; Mayer, Alexander K.

2012-01-01

In 2006, six community and technical colleges in Washington State joined the innovative national reform initiative called Achieving the Dream (ATD). This report describes the progress each college made in implementing ATD's "culture of evidence" principles for institutional improvement, examines strategies implemented by the colleges to…

Effect of pulsed progressive fluoroscopy on reduction of radiation dose in the cardiac catheterization laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Holmes, D.R. Jr.; Wondrow, M.A.; Gray, J.E.

1990-01-01

The increased application of therapeutic interventional cardiology procedures is associated with increased radiation exposure to physicians, patients and technical personnel. New advances in imaging techniques have the potential for reducing radiation exposure. A progressive scanning video system with a standard vascular phantom has been shown to decrease entrance radiation exposure. The effect of this system on reducing actual radiation exposure to physicians and technicians was assessed from 1984 through 1987. During this time, progressive fluoroscopy was added sequentially to all four adult catheterization laboratories; no changes in shielding procedures were made. During this time, the case load per physician increasedmore » by 63% and the number of percutaneous transluminal coronary angioplasty procedures (a high radiation procedure) increased by 244%. Despite these increases in both case load and higher radiation procedures, the average radiation exposure per physician declined by 37%. During the same time, the radiation exposure for technicians decreased by 35%. Pulsed progressive fluoroscopy is effective for reducing radiation exposure to catheterization laboratory physicians and technical staff.« less

Autobiographical Writing in the Technical Writing Course

ERIC Educational Resources Information Center

Gellis, Mark

2011-01-01

Professionals in the workplace are rarely asked to write autobiographical essays. Such essays, however, are an excellent tool for helping students explore their growth as professionals. This article explores the use of such essays in a technical writing class.

A Tool for Measuring NASA's Aeronautics Research Progress Toward Planned Strategic Community Outcomes

NASA Technical Reports Server (NTRS)

Tahmasebi, Farhad; Pearce, Robert

2016-01-01

Description of a tool for portfolio analysis of NASA's Aeronautics research progress toward planned community strategic Outcomes is presented. For efficiency and speed, the tool takes advantage of a function developed in Excels Visual Basic for Applications. The strategic planning process for determining the community Outcomes is also briefly discussed. Stakeholder buy-in, partnership performance, progress of supporting Technical Challenges, and enablement forecast are used as the criteria for evaluating progress toward Outcomes. A few illustrative examples of using the tool are also presented.

Nutrition and Child Growth and Development in Tunisia. Annual Progress Report, September 1, 1971--August 31, 1972.

ERIC Educational Resources Information Center

Young, Harben Boutourline

This annual report of the Yale Project describes the progress made on the nutrition and growth study of Tunisian children from September 1, 1971 through August 31, 1972. The report details: (1) the progress in analysis of the cross-sectional study data, which was completed as of June 30, 1972, and (2) the development of the present longitudinal…

Testing the Importance of Individual Growth Curves in Predicting Performance on a High-Stakes Reading Comprehension Test in Florida. Summary. REL 2014-006

ERIC Educational Resources Information Center

Petscher, Yaacov; Kershaw, Sarah; Koon, Sharon; Foorman, Barbara R.

2014-01-01

Districts and schools use progress monitoring to assess student progress, to identify students who fail to respond to intervention, and to further adapt instruction to student needs. Researchers and practitioners often use progress monitoring data to estimate student achievement growth (slope) and evaluate changes in performance over time for…

Career and Technical Education and Academic Progress at the End of High School: Evidence from the Education Longitudinal Study of 2002

ERIC Educational Resources Information Center

Bozick, Robert; Dalton, Ben

2013-01-01

This report examines the role of career and technical education (CTE) for assessing students in learning mathematics and preventing students from dropping out of high school. CTE is a wide field of educational practice that includes occupational training and career preparation offered in formats ranging from individual courses to comprehensive…

easyCBM[R] Mathematics Criterion Related Validity Evidence: Oregon State Test. Technical Report #1011

ERIC Educational Resources Information Center

Anderson, Daniel; Alonzo, Julie; Tindal, Gerald

2010-01-01

In this technical report, we present the results of a study examining the relation between the math measures available on the easyCBM[R] online benchmark and progress monitoring assessment system and the Oregon statewide assessment of mathematics. Designed for use within a response to intervention (RTI) framework, easyCBM[R] is intended to help…

New York City School Survey 2008-2010: Assessing the Reliability and Validity of a Progress Report Measure. Technical Appendices

ERIC Educational Resources Information Center

Nathanson, Lori; Cole, Rachel; Kemple, James J.; Lent, Jessica; McCormick, Meghan; Segeritz, Micha

2013-01-01

The Research Alliance for New York City Schools examined Department of Education (DOE) School Survey data from 2008-2010 to better understand the richness and complexities of the information elicited by the Survey from parents, students, and teachers. This document provides the appendices to the technical report "New York City School Survey…

The 1992 Research/Technology report

NASA Technical Reports Server (NTRS)

1992-01-01

The 1992 Research & Technology report is organized so that a broad cross section of the community can readily use it. A short introductory paragraph begins each article and will prove to be an invaluable reference tool for the layperson. The approximately 200 articles summarize the progress made during the year in various technical areas and portray the technical and administrative support associated with Lewis technology programs.

Trends in Articulation Arrangements for Technical and Vocational Education in the South East Asian Region.

ERIC Educational Resources Information Center

Haas, Adrian R.

Trends in articulation arrangements for technical and vocational education (TVE) in the South East Asia region were studied. A key feature of articulation is the existence of pathways that allow graduates of one course of study to progress to other courses. Effective articulation opens up advancement for individuals and helps to create a flexible…

Longitudinal Surveys of Australian Youth (LSAY) 1998 Cohort: Wave 12 (2009)--Frequency Tables. Technical Report 58B

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2010

2010-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the frequency tables for the LSAY 1998 cohort Wave 12 (2009) data set. [For the accompanying questionnaire, "Longitudinal Surveys…

Longitudinal Surveys of Australian Youth (LSAY): 2003 Cohort Wave 7 (2009)--Frequency Tables. Technical Report 57B

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2010

2010-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the frequency tables for the LSAY 2003 cohort Wave 7 (2009) data set. [For the related questionnaire, see ED512164.

Longitudinal Surveys of Australian Youth (LSAY) 2009 Cohort: Wave 3 (2011)--Frequency Tables. Technical Report 72B

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2012

2012-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the frequency tables for the LSAY 2009 cohort Wave 3 (2011) data set. [For the related questionnaire, see ED536306.

Longitudinal Surveys of Australian Youth (LSAY) 2003 Cohort: Wave 7 (2009)--Questionnaire. Technical Report 57A

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2010

2010-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the questionnaire for the LSAY 2003 cohort Wave 7 (2009) data set. [For the related frequency tables, see ED512163.

Making the Good Even Better: Feedback from easyCBM Focus Groups, School Year 2009/2010. Technical Report # 1001

ERIC Educational Resources Information Center

Alonzo, Julie; Tindal, Gerald; Lai, Cheng-Fei

2010-01-01

This technical report provides a summary of feedback from teachers, administrators, and support personnel who used the easyCBM progress monitoring and benchmark assessment system during school year 2009/2010. Data were gathered from semi-structured focus groups conducted during the 2010 easyCBM August Institute at the University of Oregon. Results…

Longitudinal Surveys of Australian Youth (LSAY): 2006 Cohort Wave 4 (2009)--Frequency Tables. Technical Report 56B

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2010

2010-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the frequency tables for the LSAY 2006 cohort Wave 4 (2009) data set. [For the "Longitudinal Surveys of Australian Youth (LSAY):…

Longitudinal Surveys of Australian Youth (LSAY): 2006 Cohort Wave 4 (2009)--Questionnaire. Technical Report 56A

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2010

2010-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the questionnaire for the LSAY 2006 cohort Wave 4 (2009) data set. [For the "Longitudinal Surveys of Australian Youth (LSAY):…

Establishment of the Center for Advanced Separation Technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Christopher E. Hull

2006-09-30

This Final Technical Report covers the eight sub-projects awarded in the first year and the five projects awarded in the second year of Cooperative Agreement DE-FC26-01NT41091: Establishment of the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

Progress Report on Reactivity Analyses (October-December Test Data). Beginning Teacher Evaluation Study. Technical Note Series. Technical Note III-5.

ERIC Educational Resources Information Center

Filby, Nikola N.

The development and refinement of the measures of student achievement in reading and mathematics for the Beginning Teacher Evaluation Study are described. The concept of reactivity to instruction is introduced: the tests used to evaluate instructional processes must be sensitive indicators of classroom learning overtime. Data collection activities…

First results of ground-based LWIR hyperspectral imaging remote gas detection

NASA Astrophysics Data System (ADS)

Zheng, Wei-jian; Lei, Zheng-gang; Yu, Chun-chao; Wang, Hai-yang; Fu, Yan-peng; Liao, Ning-fang; Su, Jun-hong

2014-11-01

The new progress of ground-based long-wave infrared remote sensing is presented. The LWIR hyperspectral imaging by using the windowing spatial and temporal modulation Fourier spectroscopy, and the results of outdoor ether gas detection, verify the features of LWIR hyperspectral imaging remote sensing and technical approach. It provides a new technical means for ground-based gas remote sensing.

Review of Web-Based Technical Documentation Processes. FY07 NAEP-QA Special Study Report. TR-08-17

ERIC Educational Resources Information Center

Gribben, Monica; Wise, Lauress; Becker, D. E.

2008-01-01

Beginning with the 2000 and 2001 National Assessment of Educational Progress (NAEP) assessments, the National Center for Education Statistics (NCES) has made technical documentation available on the worldwide web at http://nces.ed.gov/nationsreportcard/tdw/. The web-based documentation is designed to be less dense and more accessible than prior…

On the relationship between tumour growth rate and survival in non-small cell lung cancer.

PubMed

Mistry, Hitesh B

2017-01-01

A recurrent question within oncology drug development is predicting phase III outcome for a new treatment using early clinical data. One approach to tackle this problem has been to derive metrics from mathematical models that describe tumour size dynamics termed re-growth rate and time to tumour re-growth. They have shown to be strong predictors of overall survival in numerous studies but there is debate about how these metrics are derived and if they are more predictive than empirical end-points. This work explores the issues raised in using model-derived metric as predictors for survival analyses. Re-growth rate and time to tumour re-growth were calculated for three large clinical studies by forward and reverse alignment. The latter involves re-aligning patients to their time of progression. Hence, it accounts for the time taken to estimate re-growth rate and time to tumour re-growth but also assesses if these predictors correlate to survival from the time of progression. I found that neither re-growth rate nor time to tumour re-growth correlated to survival using reverse alignment. This suggests that the dynamics of tumours up until disease progression has no relationship to survival post progression. For prediction of a phase III trial I found the metrics performed no better than empirical end-points. These results highlight that care must be taken when relating dynamics of tumour imaging to survival and that bench-marking new approaches to existing ones is essential.

The Environment and Directed Technical Change†

PubMed Central

Acemoglu, Daron; Aghion, Philippe; Bursztyn, Leonardo

2015-01-01

This paper introduces endogenous and directed technical change in a growth model with environmental constraints. The final good is produced from “dirty” and “clean” inputs. We show that: (i) when inputs are sufficiently substitutable, sustainable growth can be achieved with temporary taxes/subsidies that redirect innovation toward clean inputs; (ii) optimal policy involves both “carbon taxes” and research subsidies, avoiding excessive use of carbon taxes; (iii) delay in intervention is costly, as it later necessitates a longer transition phase with slow growth; and (iv) use of an exhaustible resource in dirty input production helps the switch to clean innovation under laissez-faire. (JEL O33, O44, Q30, Q54, Q56, Q58) PMID:26719595

The Environment and Directed Technical Change.

PubMed

Acemoglu, Daron; Aghion, Philippe; Bursztyn, Leonardo; Hemous, David

2012-02-01

This paper introduces endogenous and directed technical change in a growth model with environmental constraints. The final good is produced from "dirty" and "clean" inputs. We show that: (i) when inputs are sufficiently substitutable, sustainable growth can be achieved with temporary taxes/subsidies that redirect innovation toward clean inputs; (ii) optimal policy involves both "carbon taxes" and research subsidies, avoiding excessive use of carbon taxes; (iii) delay in intervention is costly, as it later necessitates a longer transition phase with slow growth; and (iv) use of an exhaustible resource in dirty input production helps the switch to clean innovation under laissez-faire. (JEL O33, O44, Q30, Q54, Q56, Q58).

Professional technical standards in colleges and schools of pharmacy.

PubMed

Berry, Tricia M; Chichester, Clinton O; Lundquist, Lisa M; Sanoski, Cynthia A; Woodward, Donald A; Worley, Marcia M; Early, Johnnie L

2011-04-11

To determine the prevalence, characteristics, and use of professional technical standards among colleges and schools of pharmacy accredited by the Accreditation Council for Pharmacy Education (ACPE). The Web site of every college and school of pharmacy accredited by ACPE was searched to identify information regarding the availability, content, and use of technical standards and to obtain demographic information. Information was obtained from all of the 114 colleges and schools of pharmacy and 67 (59%) had technical standards in place. Common themes for technical standards were: observation; communication; motor; intellectual, conceptual, integrative and quantitative abilities; and behavioral and social attributes. Of those colleges and schools with technical standards, 61 (91%) had standards that addressed all 5 of these themes and 34 (51%) specified that the technical standards were used in their admission, progression, and graduation procedures. More than half of the colleges and schools of pharmacy examined in this study have technical standards; however, 41% have yet to develop and implement them. Colleges and schools of pharmacy looking for guidance in technical standards development could use the technical standards themes identified in this study.

Professional Technical Standards in Colleges and Schools of Pharmacy

PubMed Central

Berry, Tricia M.; Chichester, Clinton O.; Sanoski, Cynthia A.; Woodward, Donald A.; Worley, Marcia M.; Early, Johnnie L.

2011-01-01

Objective To determine the prevalence, characteristics, and use of professional technical standards among colleges and schools of pharmacy accredited by the Accreditation Council for Pharmacy Education (ACPE). Methods The Web site of every college and school of pharmacy accredited by ACPE was searched to identify information regarding the availability, content, and use of technical standards and to obtain demographic information. Results Information was obtained from all of the 114 colleges and schools of pharmacy and 67 (59%) had technical standards in place. Common themes for technical standards were: observation; communication; motor; intellectual, conceptual, integrative and quantitative abilities; and behavioral and social attributes. Of those colleges and schools with technical standards, 61 (91%) had standards that addressed all 5 of these themes and 34 (51%) specified that the technical standards were used in their admission, progression, and graduation procedures. Conclusion More than half of the colleges and schools of pharmacy examined in this study have technical standards; however, 41% have yet to develop and implement them. Colleges and schools of pharmacy looking for guidance in technical standards development could use the technical standards themes identified in this study. PMID:21655404

Signaling Interplay between Bone Marrow Adipose Tissue and Multiple Myeloma cells.

PubMed

Falank, Carolyne; Fairfield, Heather; Reagan, Michaela R

2016-01-01

In the year 2000, Hanahan and Weinberg (1) defined the six Hallmarks of Cancer as: self-sufficiency in growth signals, evasion of apoptosis, insensitivity to antigrowth mechanisms, tissue invasion and metastasis, limitless replicative potential, and sustained angiogenesis. Eleven years later, two new Hallmarks were added to the list (avoiding immune destruction and reprograming energy metabolism) and two new tumor characteristics (tumor-promoting inflammation and genome instability and mutation) (2). In multiple myeloma (MM), a destructive cancer of the plasma cell that grows predominantly in the bone marrow (BM), it is clear that all these hallmarks and characteristics are in play, contributing to tumor initiation, drug resistance, disease progression, and relapse. Bone marrow adipose tissue (BMAT) is a newly recognized contributor to MM oncogenesis and disease progression, potentially affecting MM cell metabolism, immune action, inflammation, and influences on angiogenesis. In this review, we discuss the confirmed and hypothetical contributions of BMAT to MM development and disease progression. BMAT has been understudied due to technical challenges and a previous lack of appreciation for the endocrine function of this tissue. In this review, we define the dynamic, responsive, metabolically active BM adipocyte. We then describe how BMAT influences MM in terms of: lipids/metabolism, hypoxia/angiogenesis, paracrine or endocrine signaling, and bone disease. We then discuss the connection between BMAT and systemic inflammation and potential treatments to inhibit the feedback loops between BM adipocytes and MM cells that support MM progression. We aim for researchers to use this review to guide and help prioritize their experiments to develop better treatments or a cure for cancers, such as MM, that associate with and may depend on BMAT.

Signaling Interplay between Bone Marrow Adipose Tissue and Multiple Myeloma cells

PubMed Central

Falank, Carolyne; Fairfield, Heather; Reagan, Michaela R.

2016-01-01

In the year 2000, Hanahan and Weinberg (1) defined the six Hallmarks of Cancer as: self-sufficiency in growth signals, evasion of apoptosis, insensitivity to antigrowth mechanisms, tissue invasion and metastasis, limitless replicative potential, and sustained angiogenesis. Eleven years later, two new Hallmarks were added to the list (avoiding immune destruction and reprograming energy metabolism) and two new tumor characteristics (tumor-promoting inflammation and genome instability and mutation) (2). In multiple myeloma (MM), a destructive cancer of the plasma cell that grows predominantly in the bone marrow (BM), it is clear that all these hallmarks and characteristics are in play, contributing to tumor initiation, drug resistance, disease progression, and relapse. Bone marrow adipose tissue (BMAT) is a newly recognized contributor to MM oncogenesis and disease progression, potentially affecting MM cell metabolism, immune action, inflammation, and influences on angiogenesis. In this review, we discuss the confirmed and hypothetical contributions of BMAT to MM development and disease progression. BMAT has been understudied due to technical challenges and a previous lack of appreciation for the endocrine function of this tissue. In this review, we define the dynamic, responsive, metabolically active BM adipocyte. We then describe how BMAT influences MM in terms of: lipids/metabolism, hypoxia/angiogenesis, paracrine or endocrine signaling, and bone disease. We then discuss the connection between BMAT and systemic inflammation and potential treatments to inhibit the feedback loops between BM adipocytes and MM cells that support MM progression. We aim for researchers to use this review to guide and help prioritize their experiments to develop better treatments or a cure for cancers, such as MM, that associate with and may depend on BMAT. PMID:27379019

Physiological and Growth Characteristics of Shewanella Species

DTIC Science & Technology

2016-05-01

AFCEC-CX-TY-TR-2016-0016 PHYSIOLOGICAL AND GROWTH CHARACTERISTICS OF SHEWANELLA SPECIES Karen Farrington, D. Matthew Eby, Susan Sizemore...Technical Report 01 March 2012 - 01 March 2014 Physiological and growth characteristics of Shewanella species FA4819-11-C-0003 Karen Farrington (1...unconventional operating temperatures. Secondly, the unusual growth characteristics of another Shewanella sp., Shewanella japonica, were investigated

Critical Review of Technical Questions Facing Low Impact Development and Green Infrastructure: A Perspective from the Great Plains.

PubMed

Vogel, Jason R; Moore, Trisha L; Coffman, Reid R; Rodie, Steven N; Hutchinson, Stacy L; McDonough, Kelsey R; McLemore, Alex J; McMaine, John T

2015-09-01

Since its inception, Low Impact Development (LID) has become part of urban stormwater management across the United States, marking progress in the gradual transition from centralized to distributed runoff management infrastructure. The ultimate goal of LID is full, cost-effective implementation to maximize watershed-scale ecosystem services and enhance resilience. To reach that goal in the Great Plains, the multi-disciplinary author team presents this critical review based on thirteen technical questions within the context of regional climate and socioeconomics across increasing complexities in scale and function. Although some progress has been made, much remains to be done including continued basic and applied research, development of local LID design specifications, local demonstrations, and identifying funding mechanisms for these solutions. Within the Great Plains and beyond, by addressing these technical questions within a local context, the goal of widespread acceptance of LID can be achieved, resulting in more effective and resilient stormwater management.

Balancing the health workforce: breaking down overall technical change into factor technical change for labour-an empirical application to the Dutch hospital industry.

PubMed

Blank, Jos L T; van Hulst, Bart L

2017-02-17

Well-trained, well-distributed and productive health workers are crucial for access to high-quality, cost-effective healthcare. Because neither a shortage nor a surplus of health workers is wanted, policymakers use workforce planning models to get information on future labour markets and adjust policies accordingly. A neglected topic of workforce planning models is productivity growth, which has an effect on future demand for labour. However, calculating productivity growth for specific types of input is not as straightforward as it seems. This study shows how to calculate factor technical change (FTC) for specific types of input. The paper first theoretically derives FTCs from technical change in a consistent manner. FTC differs from a ratio of output and input, in that it deals with the multi-input, multi-output character of the production process in the health sector. Furthermore, it takes into account substitution effects between different inputs. An application of the calculation of FTCs is given for the Dutch hospital industry for the period 2003-2011. A translog cost function is estimated and used to calculate technical change and FTC for individual inputs, especially specific labour inputs. The results show that technical change increased by 2.8% per year in Dutch hospitals during 2003-2011. FTC differs amongst the various inputs. The FTC of nursing personnel increased by 3.2% per year, implying that fewer nurses were needed to let demand meet supply on the labour market. Sensitivity analyses show consistent results for the FTC of nurses. Productivity growth, especially of individual outputs, is a neglected topic in workforce planning models. FTC is a productivity measure that is consistent with technical change and accounts for substitution effects. An application to the Dutch hospital industry shows that the FTC of nursing personnel outpaced technical change during 2003-2011. The optimal input mix changed, resulting in fewer nurses being needed to let demand meet supply on the labour market. Policymakers should consider using more detailed and specific data on the nature of technical change when forecasting the future demand for health workers.

Do failures in non-technical skills contribute to fatal medical accidents in Japan? A review of the 2010-2013 national accident reports.

PubMed

Uramatsu, Masashi; Fujisawa, Yoshikazu; Mizuno, Shinya; Souma, Takahiro; Komatsubara, Akinori; Miki, Tamotsu

2017-02-16

We sought to clarify how large a proportion of fatal medical accidents can be considered to be caused by poor non-technical skills, and to support development of a policy to reduce number of such accidents by making recommendations about possible training requirements. Summaries of reports of fatal medical accidents, published by the Japan Medical Safety Research Organization, were reviewed individually. Three experienced clinicians and one patient safety expert conducted the reviews to determine the cause of death. Views of the patient safety expert were given additional weight in the overall determination. A total of 73 summary reports of fatal medical accidents were reviewed. These reports had been submitted by healthcare organisations across Japan to the Japan Medical Safety Research Organization between April 2010 and March 2013. The cause of death in fatal medical accidents, categorised into technical skills, non-technical skills and inevitable progress of disease were evaluated. Non-technical skills were further subdivided into situation awareness, decision making, communication, team working, leadership, managing stress and coping with fatigue. Overall, the cause of death was identified as non-technical skills in 34 cases (46.6%), disease progression in 33 cases (45.2%) and technical skills in two cases (5.5%). In two cases, no consensual determination could be achieved. Further categorisation of cases of non-technical skills were identified as 14 cases (41.2%) of problems with situation awareness, eight (23.5%) with team working and three (8.8%) with decision making. These three subcategories, or combinations of them, were identified as the cause of death in 33 cases (97.1%). Poor non-technical skills were considered to be a significant cause of adverse events in nearly half of the fatal medical accidents examined. Improving non-technical skills may be effective for reducing accidents, and training in particular subcategories of non-technical skills may be especially relevant. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Next Generation Attenuation Relationships for the Eastern United States (NGA-East)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mahin, Stephen; Bozorgnia, Yousef

2016-04-11

This is a progress report to DOE for project Next Generation Attenuation for Central & Eastern US (NGA-East).This progress report consists of numerous monthly progress segments starting June 1, 2010 until December 31, 2015. Please note: the December 2015 progress report was issued in January 2016 due to the final university financial reporting at the end of this project. For each month, there is a technical progress list, and an update on the financial progress of the project. As you know, this project is jointly funded by the DOE, US Nuclear Regulatory Commission (NRC) and Electric Power Research Institute (EPRI).more » Thus, each segment includes financial progress for these three funding agencies.« less

Technical Feasibility Aspects of the Geothermal Resource Reporting Methodology (GRRM)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Badgett, Alex; Young, Katherine R; Dobson, Patrick F.

This paper reviews the technical assessment of the Geothermal Research Reporting Methodology (GRRM, http://en.openei.org/wiki/GRRM) being developed for reporting geothermal resources and project progress. The goal of the methodology is to provide the U.S. Department of Energy's Geothermal Technologies Office (GTO) with a consistent and comprehensible means of evaluating the impacts of its funding programs. The GRRM is designed to provide uniform assessment criteria for geothermal resource grades and developmental phases of geothermal resource exploration and development. This resource grade system provides information on twelve attributes of geothermal resource locations (e.g., temperature, permeability, land access) to indicate potential for geothermal development.more » The GTO plans to use these Protocols to help quantitatively identify the greatest barriers to geothermal development, develop measureable program goals that will have the greatest impact to geothermal deployment, objectively evaluate proposals based (in part) on a project's ability to contribute to program goals, monitor project progress, and report on GTO portfolio performance. The GRRM assesses three areas of geothermal potential: geological, socio-economic, and technical. Previous work and publications have discussed the work done on the geological aspects of this methodology (Young et al. 2015c); this paper details the development of the technical assessment of the GRRM. Technical development attributes considered include: reservoir management, drilling, logistics, and power conversion.« less

Effect of viewing distance on 3D fatigue caused by viewing mobile 3D content

NASA Astrophysics Data System (ADS)

Mun, Sungchul; Lee, Dong-Su; Park, Min-Chul; Yano, Sumio

2013-05-01

With an advent of autostereoscopic display technique and increased needs for smart phones, there has been a significant growth in mobile TV markets. The rapid growth in technical, economical, and social aspects has encouraged 3D TV manufacturers to apply 3D rendering technology to mobile devices so that people have more opportunities to come into contact with many 3D content anytime and anywhere. Even if the mobile 3D technology leads to the current market growth, there is an important thing to consider for consistent development and growth in the display market. To put it briefly, human factors linked to mobile 3D viewing should be taken into consideration before developing mobile 3D technology. Many studies have investigated whether mobile 3D viewing causes undesirable biomedical effects such as motion sickness and visual fatigue, but few have examined main factors adversely affecting human health. Viewing distance is considered one of the main factors to establish optimized viewing environments from a viewer's point of view. Thus, in an effort to determine human-friendly viewing environments, this study aims to investigate the effect of viewing distance on human visual system when exposing to mobile 3D environments. Recording and analyzing brainwaves before and after watching mobile 3D content, we explore how viewing distance affects viewing experience from physiological and psychological perspectives. Results obtained in this study are expected to provide viewing guidelines for viewers, help ensure viewers against undesirable 3D effects, and lead to make gradual progress towards a human-friendly mobile 3D viewing.

Preliminary Investigations of the Application of the Early Communication Indicator (ECI) for Infants and Toddlers

ERIC Educational Resources Information Center

Greenwood, Charles R.; Carta, Judith J.; Walker, Dale; Hughes, Kere; Weathers, Mary

2006-01-01

Early interventionists are accountable for the progress of children receiving their services. Technically adequate measures of the progress of individual children are needed. While the Early Communication Indicator (ECI) for infants and toddlers is one such measure, data to support its use are limited to a single research report. In this…

Curriculum-Based Measurement in Science Learning: Vocabulary-Matching as an Indicator of Performance and Progress

ERIC Educational Resources Information Center

Espin, Christine A.; Busch, Todd W.; Lembke, Erica S.; Hampton, David D.; Seo, Kyounghee; Zukowski, Beth A.

2013-01-01

The technical adequacy of curriculum-based measures in the form of short and simple vocabulary-matching probes to predict students' performance and progress in science at the secondary level was investigated. Participants were 198 seventh-grade students from 10 science classrooms. Curriculum-based measurements (CBM) were 5-min vocabulary-matching…

Technical Adequacy of Early Numeracy Curriculum-Based Progress Monitoring Measures for Kindergarten and First-Grade Students

ERIC Educational Resources Information Center

Hampton, David D.; Lembke, Erica S.; Lee, Young-Sun; Pappas, Sandra; Chiong, Cynthia; Ginsburg, Herbert P.

2012-01-01

The purpose of this study was to examine six early numeracy measures used to monitor the mathematics progress of kindergarten and first-grade students. Seventy-one kindergarten students and 75 first-grade students were administered the measures each week. Delayed-alternate form reliability was adequate for instructional decision making on some…

Jet Crackle

DTIC Science & Technology

2015-06-23

DISTRIBUTION/AVAILABILITY STATEMENT DISTRIBUTION A 13. SUPPLEMENTARY NOTES 14. ABSTRACT Fighter jets and other aircraft with high specific thrust engines...interim, memorandum, master’s thesis , progress, quarterly, research, special, group study, etc. 3. DATES COVERED. Indicate the time during which the...State the type of report, such as final, technical, interim, memorandum, master’s thesis , progress, quarterly, research, special, group study, etc

Reading Achievement in Disadvantaged Children as a Consequence of Non Verbal Perceptual Training. Final Technical Progress Report.

ERIC Educational Resources Information Center

Elkind, David; Deblinger, Jo Ann

The theoretical orientation based on perceptual development, proposed by Piaget in 1961, is the starting point of this investigation. According to Piaget, the perception of the young child is "centered" on dominant aspects of the field. With maturity, perception becomes "decentered" and progressively freed from the field. The…

Monitoring Student Progress and Publicising the Results. Information Bank Number 1270.

ERIC Educational Resources Information Center

Jones, D. T. L.

Arguing that assessments of student progress describe the consequences of the interaction of the multitude of elements that make up the educational system, this paper examines the three-tiered assessment system used at Redhill Technical College (RTC), in Surrey, England, to fulfill diagnostic and motivational functions for the college as a whole.…

Progressive Inhibition by Water Deficit of Cell Wall Extensibility and Growth along the Elongation Zone of Maize Roots Is Related to Increased Lignin Metabolism and Progressive Stelar Accumulation of Wall Phenolics1

PubMed Central

Fan, Ling; Linker, Raphael; Gepstein, Shimon; Tanimoto, Eiichi; Yamamoto, Ryoichi; Neumann, Peter M.

2006-01-01

Water deficit caused by addition of polyethylene glycol 6000 at −0.5 MPa water potential to well-aerated nutrient solution for 48 h inhibited the elongation of maize (Zea mays) seedling primary roots. Segmental growth rates in the root elongation zone were maintained 0 to 3 mm behind the tip, but in comparison with well-watered control roots, progressive growth inhibition was initiated by water deficit as expanding cells crossed the region 3 to 9 mm behind the tip. The mechanical extensibility of the cell walls was also progressively inhibited. We investigated the possible involvement in root growth inhibition by water deficit of alterations in metabolism and accumulation of wall-linked phenolic substances. Water deficit increased expression in the root elongation zone of transcripts of two genes involved in lignin biosynthesis, cinnamoyl-CoA reductase 1 and 2, after only 1 h, i.e. before decreases in wall extensibility. Further increases in transcript expression and increased lignin staining were detected after 48 h. Progressive stress-induced increases in wall-linked phenolics at 3 to 6 and 6 to 9 mm behind the root tip were detected by comparing Fourier transform infrared spectra and UV-fluorescence images of isolated cell walls from water deficit and control roots. Increased UV fluorescence and lignin staining colocated to vascular tissues in the stele. Longitudinal bisection of the elongation zone resulted in inward curvature, suggesting that inner, stelar tissues were also rate limiting for root growth. We suggest that spatially localized changes in wall-phenolic metabolism are involved in the progressive inhibition of wall extensibility and root growth and may facilitate root acclimation to drying environments. PMID:16384904

Carbidopa abrogates L-dopa decarboxylase coactivation of the androgen receptor and delays prostate tumor progression.

PubMed

Wafa, Latif A; Cheng, Helen; Plaa, Nathan; Ghaidi, Fariba; Fukumoto, Takahiro; Fazli, Ladan; Gleave, Martin E; Cox, Michael E; Rennie, Paul S

2012-06-15

The androgen receptor (AR) plays a central role in prostate cancer progression to the castration-resistant (CR) lethal state. L-Dopa decarboxylase (DDC) is an AR coactivator that increases in expression with disease progression and is coexpressed with the receptor in prostate adenocarcinoma cells, where it may enhance AR activity. Here, we hypothesize that the DDC enzymatic inhibitor, carbidopa, can suppress DDC-coactivation of AR and retard prostate tumor growth. Treating LNCaP prostate cancer cells with carbidopa in transcriptional assays suppressed the enhanced AR transactivation seen with DDC overexpression and decreased prostate-specific antigen (PSA) mRNA levels. Carbidopa dose-dependently inhibited cell growth and decreased survival in LNCaP cell proliferation and apoptosis assays. The inhibitory effect of carbidopa on DDC-coactivation of AR and cell growth/survival was also observed in PC3 prostate cancer cells (stably expressing AR). In vivo studies demonstrated that serum PSA velocity and tumor growth rates elevated ∼2-fold in LNCaP xenografts, inducibly overexpressing DDC, were reverted to control levels with carbidopa administration. In castrated mice, treating LNCaP tumors, expressing endogenous DDC, with carbidopa delayed progression to the CR state from 6 to 10 weeks, while serum PSA and tumor growth decreased 4.3-fold and 5.4-fold, respectively. Our study is a first time demonstration that carbidopa can abrogate DDC-coactivation of AR in prostate cancer cells and tumors, decrease serum PSA, reduce tumor growth and delay CR progression. Since carbidopa is clinically approved, it may be readily used as a novel therapeutic strategy to suppress aberrant AR activity and delay prostate cancer progression. Copyright © 2011 UICC.

Phytochrome-mediated synthesis of novel growth inhibitors, A-2α and β, and dwarfism in peas.

PubMed

Noguchi, H; Hashimoto, T

1990-05-01

Variations in the content of A-2α and β, novel endogenous growth inhibitors, andcis,trans- andtrans, trans-xanthoxins were determined in 6- or 7-d-old, dark-grown seedlings of peas (Pisum sativum L. cvs. Progress No. 9, dwarf, and Alaska, tall) under various treatments with red light (R), and compared with R-induced growth inhibition. After transfer of the plants to continuous R the contents of the A-2s in cv. Progress increased after a 20-min lag, and reached plateaus after 12 h, whereas they remained almost unchanged in darkness. Both the rates of increase of the A-2s and the plateau levels were proportional to the logarithm of the irradiance applied. After a 10-min R pulse, the contents of both A-2α and β increased with the same rapidity to reach peaks after 6 h, and then gradually decreased to the initial levels after about 24 h. The effect of R was shown to be phytochrome-dependent, being nullified by far-red light. The level of neithercis,trans- nortrans,trans-xanthoxin showed such a close correlation with growth inhibition, although both xanthoxins increased as a result of phytochrome action. It is highly suggestive that the A-2s, rather than the xanthoxins, are responsible for phytochrome-dependent growth inhibition in cv. Progress. In cv. Alaska, in contrast, R-induced increase of the A-2s was rapid but slight, and could not explain the transient growth inhibition, which was found to be as large as that in cv. Progress shortly after the onset of R. The large content of the A-2s in cv. Progress in the steady state under continuous R, compared with that in cv. Alaska, may explain the dwarfism of cv. Progress.

Growth and Migration Plan for Data Insight

DTIC Science & Technology

2004-12-13

exceed 30 users. The group of users must select one person to be the technical point of contact (TPOC). All technical and business questions shall...CONTACT (TPOC) INFORMATION Name: Title: Site: Address: City: State: Zip Code: E-mail address: Business phone number: Business fax

Dynamic Contrast-Enhanced Magnetic Resonance Imaging as a Pharmacodynamic Biomarker for Pazopanib in Metastatic Renal Carcinoma.

PubMed

Sweis, Randy F; Medved, Milica; Towey, Shannon; Karczmar, Gregory S; Oto, Aytekin; Szmulewitz, Russell Z; O'Donnell, Peter H; Fishkin, Paul; Karrison, Theodore; Stadler, Walter M

2017-04-01

Traditional imaging assessment criteria might not correlate well with clinical benefit from vascular endothelial growth factor pathway-directed therapy in metastatic renal cancer. Preclinical data suggest tumor growth is preceded by a rise in K trans level, a parameter derived from dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) that reflects vascular permeability. We thus hypothesized that K trans might be a predictive biomarker for pazopanib. Patients with metastatic renal cancer were treated with pazopanib at 800 mg oral daily until disease progression. MRI of the abdomen and pelvis with a DCE-MRI sequence was obtained at baseline and every 8 weeks. Seventy-three DCE-MRI scans were completed and 66 were technically assessable. Of the 17 patients with at least 1 DCE-MRI scan after the baseline scan, 16 (94%) had a decline in K trans level. Changes in K trans compared with baseline after 1, 8, 16, and 24 weeks were -49%, -65%, -63%, and -53%, respectively (P = .0052, repeated measures analysis of variance). The median K trans nadir occurred at 8 weeks. The median progression-free survival (PFS) was 32.1 weeks. PFS was longer in patients with higher baseline K trans values (P = .036, log rank). Baseline K trans did not reach significance in a Cox proportional hazard model including clinical prognostic index and previous treatments (P = .083). We show that K trans is a pharmacodynamic biomarker for pazopanib therapy in metastatic renal cancer. Because of the small sample size, the predictive capacity of K trans recovery could not be assessed, but baseline K trans correlated with PFS. Copyright © 2016 Elsevier Inc. All rights reserved.

SAMS Acceleration Measurements on Mir From January to May 1997 (NASA Increment 4)

NASA Technical Reports Server (NTRS)

DeLombard, Richard

1998-01-01

During NASA Increment 4 (January to May 1997), about 5 gigabytes of acceleration data were collected by the Space Acceleration Measurements System (SAMS) onboard the Russian Space Station, Mir. The data were recorded on 28 optical disks which were returned to Earth on STS-84. During this increment, SAMS data were collected in the Priroda module to support the Mir Structural Dynamics Experiment (MiSDE), the Binary Colloidal Alloy Tests (BCAT), Angular Liquid Bridge (ALB), Candle Flames in Microgravity (CFM), Diffusion Controlled Apparatus Module (DCAM), Enhanced Dynamic Load Sensors (EDLS), Forced Flow Flame Spreading Test (FFFT), Liquid Metal Diffusion (LMD), Protein Crystal Growth in Dewar (PCG/Dewar), Queen's University Experiments in Liquid Diffusion (QUELD), and Technical Evaluation of MIM (TEM). This report points out some of the salient features of the microgravity environment to which these experiments were exposed. Also documented are mission events of interest such as the docked phase of STS-84 operations, a Progress engine burn, Soyuz vehicle docking and undocking, and Progress vehicle docking. This report presents an overview of the SAMS acceleration measurements recorded by 10 Hz and 100 Hz sensor heads. The analyses included herein complement those presented in previous summary reports prepared by the Principal Investigator Microgravity Services (PIMS) group.

Progress in Modeling Nonlinear Dendritic Evolution in Two and Three Dimensions, and Its Mathematical Justification

NASA Technical Reports Server (NTRS)

Tanveer, S.; Foster, M. R.

2002-01-01

We report progress in three areas of investigation related to dendritic crystal growth. Those items include: 1. Selection of tip features dendritic crystal growth; 2) Investigation of nonlinear evolution for two-sided model; and 3) Rigorous mathematical justification.

Growth through Levels

ERIC Educational Resources Information Center

Thissen, David

2015-01-01

In "Using Learning Progressions to Design Vertical Scales that Support Coherent Inferences about Student Growth" (hereafter ULR), Briggs and Peck suggest that learning progressions could be used as the basis of vertical scales with naturally benchmarked descriptions of student proficiency. They propose and provide a single example of a…

Research on the industry environmental total factor productivity in Jiangsu Province based on the SBM-SML

NASA Astrophysics Data System (ADS)

Lingfang, Sun; Han, Wang; Jian, Gong

2017-03-01

This paper uses the SBM-SML to measure the industry environmental total factor productivity in Jiangsu province of its 13 cities during 2005-2014 with SO2 emissions as the undesirable output, and discomposes the total factor productivity into the pure technical efficiency, the scale efficiency change, the pure technical change and the scale technical change. The research shows that the overall trend of the industry environmental total factor productivity is increasing in Jiangsu province during 2005-2014, the technical change is a main reason pushing up growth rates of economy, and the pure technical change is the intrinsic motivation of the technical change.Introduction.

Magnetic Earth Ionosphere Resonant Frequencies

NASA Technical Reports Server (NTRS)

Spaniol, Craig

1994-01-01

The Community College Division is pleased to report progress of NASA funded research at West Virginia State College. During this reporting period, the project research group has continued with activities to develop instrumentation capability designed to monitor resonant cavity frequencies in the atmospheric region between the Earth's surface and the ionosphere. In addition, the project's principal investigator, Dr. Craig Spaniol, and NASA technical officer, Dr. John Sutton, have written and published technical papers intended to expand the scientific and technical framework needed for project research. This research continues to provide an excellent example of government and education working together to provide significant research in the college environment. This cooperative effort has provided many students with technical project work which compliments their education.

48 CFR 742.1170-1 - General.

Code of Federal Regulations, 2013 CFR

2013-10-01

... MANAGEMENT CONTRACT ADMINISTRATION Production, Surveillance, and Reporting 742.1170-1 General. Performance... cognizant technical officer, to maintain adequate knowledge of the contractor's activities and progress in...

48 CFR 742.1170-1 - General.

Code of Federal Regulations, 2012 CFR

2012-10-01

... MANAGEMENT CONTRACT ADMINISTRATION Production, Surveillance, and Reporting 742.1170-1 General. Performance... cognizant technical officer, to maintain adequate knowledge of the contractor's activities and progress in...

48 CFR 742.1170-1 - General.

Code of Federal Regulations, 2014 CFR

2014-10-01

... MANAGEMENT CONTRACT ADMINISTRATION Production, Surveillance, and Reporting 742.1170-1 General. Performance... cognizant technical officer, to maintain adequate knowledge of the contractor's activities and progress in...

48 CFR 742.1170-1 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... MANAGEMENT CONTRACT ADMINISTRATION Production, Surveillance, and Reporting 742.1170-1 General. Performance... cognizant technical officer, to maintain adequate knowledge of the contractor's activities and progress in...

Access and Success for System Goals for People of Color in Washington Community and Technical Colleges: Progress Report. Research Report No. 05-3

ERIC Educational Resources Information Center

Washington State Board for Community and Technical Colleges, 2005

2005-01-01

This report is designed to provide information for readers, promote discussion, and set the stage for future initiatives to address outcomes for people of color. The data provided speaks to the success that Washington's community and technical colleges have achieved in increasing higher education access and participation for students of color. It…

Internal Consistency of General Outcome Measures in Grades 1-8. Technical Report # 0915

ERIC Educational Resources Information Center

Anderson, Daniel; Tindal, Gerald; Alonzo, Julie

2009-01-01

We developed alternate forms of a math test for use in both screening students at risk of failure and monitoring their progress over time. In this technical report, we present results of the screener, used in the fall of 2009. The 48-item test was aligned to the National Council of Teachers of Mathematics (NCTM) Curriculum Focal Point Standards…

Career and Technical Education: States Aligning Programs to Meet Workforce Needs. The Progress of Education Reform. Volume 15, Number 2

ERIC Educational Resources Information Center

Zinth, Jennifer Dounay

2014-01-01

Across the 50 states, career and technical education (CTE) programs at the K-12 and postsecondary levels have seen enormous policy action - 2013 alone saw at least 78 substantive policy changes via legislation, state board rules and executive orders specific to CTE and workforce development. What are the drivers behind this sudden policymaker…

The Development of Technical and Vocational Education in Malaysia--A Case Study in Quality Improvement. Case Studies on Technical and Vocational Education in Asia and the Pacific.

ERIC Educational Resources Information Center

Hee, Tieng Fok

The economic profile of Malaysia has changed from an economy mainly based on agriculture and the production of tin ore to a more balanced economy with continuing growth in the manufacturing and industrial sectors. Educational programs need to be upgraded and improved, particularly the direction and development of technical and vocational education…

Protecting Water Quality With Smart Growth Strategies and Natural Stormwater Management in Sussex County, Delaware

EPA Pesticide Factsheets

The report describes a technical assistance project that explored how smart growth and sustainable stormwater management approaches (known as green infrastructure) could be applied to Sussex County, DE.

An Online Approach to Teaching International Outsourcing in Technical Communication Classes

ERIC Educational Resources Information Center

St. Amant, Kirk

2005-01-01

The growth of international online access has given rise to a new production method--international outsourcing--that has important implications for technical communication practices. Successful interactions within international outsourcing require individuals to understand how cultural factors could affect online interactions. Today's technical…

Scientific and Technical Libraries in Kentucky.

ERIC Educational Resources Information Center

Powell, Russell H.; Gleim, David E.

Based on initial questionnaires, plus followup contacts and interviews, this survey documents for the first time the holdings, rates of growth, and information resources available at 72 of Kentucky's scientific and technical libraries. Included are library book collections that emphasize the business, economic, biological, physical, medical, and…

[The technique and technicism in surgery].

PubMed

Abaev, Iu K

2010-01-01

Characterization is given to the present-day stage of the development of surgery using complex medical technique and considerable growth of the number of laboratory-instrumental investigations is characterized. The estimation is given of the negative tendency to dehumanize medicine because of the technicism of doctors' thinking.

Nuclear Technology Division annual progress report for period ending June 30, 1972

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1972-10-01

This document is a report of progress on technical programs of the Nuclear Technology,Division of Aerojet Nuclear Company for FY 72 ending June 30, 1972. It contains abstracts or expansions of abstracts of papers which have been published within the year. In these cases, preprints or reprints of the articles available. Results of work in progress are also reported; since this work is of a preliminary nature, the authors should be contacted before including any reference to these works in other publications.

28 CFR 33.12 - Establishment of State Office.

Code of Federal Regulations, 2011 CFR

2011-07-01

... received from the Bureau of Justice Assistance, including receipt, review, processing, monitoring, progress and financial report review, technical assistance, grant adjustments, accounting, auditing, and fund...

28 CFR 33.12 - Establishment of State Office.

Code of Federal Regulations, 2010 CFR

2010-07-01

... received from the Bureau of Justice Assistance, including receipt, review, processing, monitoring, progress and financial report review, technical assistance, grant adjustments, accounting, auditing, and fund...

Growth of Azotobacter vinelandii in a solid-state fermentation of technical lignin.

PubMed

Zhang, Xiaoyong; Zhao, Hua; Zhang, Jianan; Li, Zuohu

2004-10-01

Azotobacter vinelandii was cultured on technical lignin, derived from Kraft pulping processes, for biofertilizer production in solid-state fermentation. The effects of the ratio of technical lignin to corn straw, initial water content, and material bed depth on the microorganisms were studied in detail. At 30 degrees C, technical lignin to corn straw at the ratio of 1:0.75, the bed depth of 5 cm, and 67% moisture content, A. vinelandii was grown and reached 4.2 x 10(10) cfu g(-1) dry rot after 36 h.

41. Photocopy of progress photograph ca. 1974, photographer unknown. Original ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

41. Photocopy of progress photograph ca. 1974, photographer unknown. Original photograph Property of United States Air Force, 21" Space Command. This is the source for views 41 to 47. CAPE COD AIR STATION PAVE PAWS FACILITY - SHOWING BUILDING "RED IRON" STEEL STRUCTURE NEARING COMPLETION. - Cape Cod Air Station, Technical Facility-Scanner Building & Power Plant, Massachusetts Military Reservation, Sandwich, Barnstable County, MA

Center for Information Services Fourth Quarterly Progress Report, Phase IIB; Detailed Design and Prototype Development, 1 October 1971 to 31 December 1971.

ERIC Educational Resources Information Center

Kehl, W. B.; And Others

The administrative activity, including organization, staff, budget and external contacts, and the technical progress of IPS development, experimental service, workshops, documentation and related activities of the Center for Information Services (at the University of California, Los Angeles) are reported upon in this document. Pages 9 and 10 may…

Curriculum-Based Measurement: Developing a Computer-Based Assessment Instrument for Monitoring Student Reading Progress on Multiple Indicators

ERIC Educational Resources Information Center

Forster, Natalie; Souvignier, Elmar

2011-01-01

The purpose of this study was to examine the technical adequacy of a computer-based assessment instrument which is based on hierarchical models of text comprehension for monitoring student reading progress following the Curriculum-Based Measurement (CBM) approach. At intervals of two weeks, 120 third-grade students finished eight CBM tests. To…

Career Technical Education Pathways Initiative

ERIC Educational Resources Information Center

California Community Colleges, Chancellor's Office, 2013

2013-01-01

California's education system--the largest in the United States--is an essential resource for ensuring strong economic growth in the state. The Career Technical Education Pathways Initiative (referred to as the Initiative in this report), which became law in 2005, brings together community colleges, K-12 school districts, employers, organized…

Our built and natural environments : a technical review of the interactions between land use, transportation, and environmental quality

DOT National Transportation Integrated Search

2001-01-01

In recent years interest has grown in Smart Growth as a mechanism for improving environmental quality. In Our Built and Natural Environments, the U.S. Environmental Protection Agency (EPA) summarizes technical research on the relationship between the...

75 FR 4122 - Data Collection Available for Public Comments and Recommendations

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-26

... disadvantaged businesses with management and technical assistance to enhance their ability to compete in the..., and management and technical assistance through 7(j) designated funds) to foster the business growth... questions to legal land insurance, business planning, financing, marketing and business operations) that...

Africa's Agenda for Action: Reform Policies, Renew Progress.

ERIC Educational Resources Information Center

Johanson, Richard K., Ed.

1987-01-01

Unprecedented population growth and mounting fiscal austerity in Africa is causing a decline in the significant increases in educational progress, especially as measured by the median literacy rate, which were made between 1962 and 1985. Planning and implementation of educational programs carefully designed to effect economic growth is one path…

Recent advances in understanding Streptomyces

PubMed Central

Chater, Keith F.

2016-01-01

About 2,500 papers dated 2014–2016 were recovered by searching the PubMed database for Streptomyces, which are the richest known source of antibiotics. This review integrates around 100 of these papers in sections dealing with evolution, ecology, pathogenicity, growth and development, stress responses and secondary metabolism, gene expression, and technical advances. Genomic approaches have greatly accelerated progress. For example, it has been definitively shown that interspecies recombination of conserved genes has occurred during evolution, in addition to exchanges of some of the tens of thousands of non-conserved accessory genes. The closeness of the association of Streptomyces with plants, fungi, and insects has become clear and is reflected in the importance of regulators of cellulose and chitin utilisation in overall Streptomyces biology. Interestingly, endogenous cellulose-like glycans are also proving important in hyphal growth and in the clumping that affects industrial fermentations. Nucleotide secondary messengers, including cyclic di-GMP, have been shown to provide key input into developmental processes such as germination and reproductive growth, while late morphological changes during sporulation involve control by phosphorylation. The discovery that nitric oxide is produced endogenously puts a new face on speculative models in which regulatory Wbl proteins (peculiar to actinobacteria) respond to nitric oxide produced in stressful physiological transitions. Some dramatic insights have come from a new model system for Streptomyces developmental biology, Streptomyces venezuelae, including molecular evidence of very close interplay in each of two pairs of regulatory proteins. An extra dimension has been added to the many complexities of the regulation of secondary metabolism by findings of regulatory crosstalk within and between pathways, and even between species, mediated by end products. Among many outcomes from the application of chromosome immunoprecipitation sequencing (ChIP-seq) analysis and other methods based on “next-generation sequencing” has been the finding that 21% of Streptomyces mRNA species lack leader sequences and conventional ribosome binding sites. Further technical advances now emerging should lead to continued acceleration of knowledge, and more effective exploitation, of these astonishing and critically important organisms. PMID:27990276

Social Well-Being and Rural Community Development: Issues in Policy and Theory.

ERIC Educational Resources Information Center

Wilkinson, Kenneth P.

Rural development literature yields three images of improved social well-being--economic technical growth, human-interpersonal growth, and environmental-quality protection. While the economic growth dimension of rural development has received much attention, little is known about the structural conditions in the social organization or the kinds of…

Preliminary technical results review of FY81 experiments. Volume 1: Fiscal year 1981/82 spring small grains pilot experiment. [Canada and the United States

NASA Technical Reports Server (NTRS)

1981-01-01

Technical progress made in the foreign commodity production forecasting for the advancement of spring small grains (SSG) area estimation is reported with emphasis on results achieved since the last AgRISTARS level semiannual review. Major objectives and accomplishments are reviewed and the experiment is described. The technical approach data assessment, and data systems used are considered. Results of the group approach comparison study are presented along with preliminary aggregation results for SSG processing procedures. The outlook for the future is assessed.

CPTSC 2001: Managing Change and Growth in Technical and Scientific Communication. Proceedings of the Annual Conference of the Council for Programs in Technical and Scientific Communication (28th, Pittsburgh, Pennsylvania, October 11-13, 2001).

ERIC Educational Resources Information Center

Maylath, Bruce, Ed.

This proceedings presents 43 papers delivered at the 2001 annual meeting of the Council for Programs in Technical and Scientific Communication (CPTSC). Papers in the proceedings include the following: "Act IV: On Being Less Invisible" (Bill Karis); "Building a Community of Professional Communicators by Mapping Needs and Assets"…

JPRS Report, Science & Technology, USSR: Science & Technology Policy.

DTIC Science & Technology

1987-07-07

fully reflect the end results of scientific and technical progress. The formation of the unified fund for the development of science and technology ...209058 JPRS-UST-87-009 7 JULY 1987 /ffifr FOREIGN BROADCAST INFORMATION SERVICE JPRS Repor Science & Technology USSR: Science... Technology Policy 19980715 121 REPRODUCED BY U.S. DEPARTMENTOF COMMERCE NATIONAL TECHNICAL •^ INFORMATIONSERVICE A rf *r*lQ ürjA T Tw» SPRINGFIELD, VA

Advances in optimal routing through computer networks

NASA Technical Reports Server (NTRS)

Paz, I. M.

1977-01-01

The optimal routing problem is defined. Progress in solving the problem during the previous decade is reviewed, with special emphasis on technical developments made during the last few years. The relationships between the routing, the throughput, and the switching technology used are discussed and their future trends are reviewed. Economic aspects are also briefly considered. Modern technical approaches for handling the routing problems and, more generally, the flow control problems are reviewed.

Effect of Food Regulation on the Spanish Food Processing Industry: A Dynamic Productivity Analysis.

PubMed

Kapelko, Magdalena; Oude Lansink, Alfons; Stefanou, Spiro E

2015-01-01

This article develops the decomposition of the dynamic Luenberger productivity growth indicator into dynamic technical change, dynamic technical inefficiency change and dynamic scale inefficiency change in the dynamic directional distance function context using Data Envelopment Analysis. These results are used to investigate for the Spanish food processing industry the extent to which dynamic productivity growth and its components are affected by the introduction of the General Food Law in 2002 (Regulation (EC) No 178/2002). The empirical application uses panel data of Spanish meat, dairy, and oils and fats industries over the period 1996-2011. The results suggest that in the oils and fats industry the impact of food regulation on dynamic productivity growth is negative initially and then positive over the long run. In contrast, the opposite pattern is observed for the meat and dairy processing industries. The results further imply that firms in the meat processing and oils and fats industries face similar impacts of food safety regulation on dynamic technical change, dynamic inefficiency change and dynamic scale inefficiency change.

Effect of Food Regulation on the Spanish Food Processing Industry: A Dynamic Productivity Analysis

PubMed Central

Kapelko, Magdalena; Lansink, Alfons Oude; Stefanou, Spiro E.

2015-01-01

This article develops the decomposition of the dynamic Luenberger productivity growth indicator into dynamic technical change, dynamic technical inefficiency change and dynamic scale inefficiency change in the dynamic directional distance function context using Data Envelopment Analysis. These results are used to investigate for the Spanish food processing industry the extent to which dynamic productivity growth and its components are affected by the introduction of the General Food Law in 2002 (Regulation (EC) No 178/2002). The empirical application uses panel data of Spanish meat, dairy, and oils and fats industries over the period 1996-2011. The results suggest that in the oils and fats industry the impact of food regulation on dynamic productivity growth is negative initially and then positive over the long run. In contrast, the opposite pattern is observed for the meat and dairy processing industries. The results further imply that firms in the meat processing and oils and fats industries face similar impacts of food safety regulation on dynamic technical change, dynamic inefficiency change and dynamic scale inefficiency change. PMID:26057878

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rhinefrank, Kenneth; Lamb, Bradford; Prudell, Joseph

This Project aims to satisfy objectives of the DOE’s Water Power Program by completing a system detailed design (SDD) and other important activities in the first phase of a utility-scale grid-connected ocean wave energy demonstration. In early 2012, Columbia Power (CPwr) had determined that further cost and performance optimization was necessary in order to commercialize its StingRAY wave energy converter (WEC). CPwr’s progress toward commercialization, and the requisite technology development path, were focused on transitioning toward a commercial-scale demonstration. This path required significant investment to be successful, and the justification for this investment required improved annual energy production (AEP) andmore » lower capital costs. Engineering solutions were developed to address these technical and cost challenges, incorporated into a proposal to the US Department of Energy (DOE), and then adapted to form the technical content and statement of project objectives of the resulting Project (DE-EE0005930). Through Project cost-sharing and technical collaboration between DOE and CPwr, and technical collaboration with Oregon State University (OSU), National Renewable Energy Lab (NREL) and other Project partners, we have demonstrated experimentally that these conceptual improvements have merit and made significant progress towards a certified WEC system design at a selected and contracted deployment site at the Wave Energy Test Site (WETS) at the Marine Corps Base in Oahu, HI (MCBH).« less

Environmentally friendly use of non-coal ashes in Sweden.

PubMed

Ribbing, C

2007-01-01

The Swedish Thermal Engineering Research Institute (Värmeforsk) initiated an applied research program "Environmentally friendly use of non-coal ashes", in 2002. The program aims at increasing knowledge on the by-products of energy production and their application. The goal of formulating technical and environmental guidelines and assessments is a major point of the program, which is supported by about forty authorities and private organisations. The programme has been divided into four areas: recycling of ashes to forests, geotechnical applications, use in landfilling, and environmental aspects and chemistry. Among all results obtained, the following progress is shown: *Evidence for the positive effects of spreading ashes on forest growth. *A proposal for environmental guidelines on the utilisation of ashes in construction. *A handbook for using non-coal fly ashes in unpaved roads. *Technical and environmental assessments of MSWI bottom ashes in road construction. *Development of the use of ashes with municipal wastewater sludge as a cover for landfills and mine tailings. *Use of ashes from bio-fuels in concrete and replacement of cement in stoop mining. *A method to classify those by-products from combustion that have mirror entries in the EWC as a hazardous or non-hazardous compound. The Ash Programme has also made it possible to increase knowledge on ashes as valuable materials, on quality assurance and on markets for recovered materials.

Robot-assisted vitreoretinal surgery: current perspectives

PubMed Central

Roizenblatt, Marina; Edwards, Thomas L; Gehlbach, Peter L

2018-01-01

Vitreoretinal microsurgery is among the most technically challenging of the minimally invasive surgical techniques. Exceptional precision is required to operate on micron scale targets presented by the retina while also maneuvering in a tightly constrained and fragile workspace. These challenges are compounded by inherent limitations of the unassisted human hand with regard to dexterity, tremor and precision in positioning instruments. The limited human ability to visually resolve targets on the single-digit micron scale is a further limitation. The inherent attributes of robotic approaches therefore, provide logical, strategic and promising solutions to the numerous challenges associated with retinal microsurgery. Robotic retinal surgery is a rapidly emerging technology that has witnessed an exponential growth in capabilities and applications over the last decade. There is now a worldwide movement toward evaluating robotic systems in an expanding number of clinical applications. Coincident with this expanding application is growth in the number of laboratories committed to “robotic medicine”. Recent technological advances in conventional retina surgery have also led to tremendous progress in the surgeon’s capabilities, enhanced outcomes, a reduction of patient discomfort, limited hospitalization and improved safety. The emergence of robotic technology into this rapidly advancing domain is expected to further enhance important aspects of the retinal surgery experience for the patients, surgeons and society. PMID:29527537

Robot-assisted vitreoretinal surgery: current perspectives.

PubMed

Roizenblatt, Marina; Edwards, Thomas L; Gehlbach, Peter L

2018-01-01

Vitreoretinal microsurgery is among the most technically challenging of the minimally invasive surgical techniques. Exceptional precision is required to operate on micron scale targets presented by the retina while also maneuvering in a tightly constrained and fragile workspace. These challenges are compounded by inherent limitations of the unassisted human hand with regard to dexterity, tremor and precision in positioning instruments. The limited human ability to visually resolve targets on the single-digit micron scale is a further limitation. The inherent attributes of robotic approaches therefore, provide logical, strategic and promising solutions to the numerous challenges associated with retinal microsurgery. Robotic retinal surgery is a rapidly emerging technology that has witnessed an exponential growth in capabilities and applications over the last decade. There is now a worldwide movement toward evaluating robotic systems in an expanding number of clinical applications. Coincident with this expanding application is growth in the number of laboratories committed to "robotic medicine". Recent technological advances in conventional retina surgery have also led to tremendous progress in the surgeon's capabilities, enhanced outcomes, a reduction of patient discomfort, limited hospitalization and improved safety. The emergence of robotic technology into this rapidly advancing domain is expected to further enhance important aspects of the retinal surgery experience for the patients, surgeons and society.

Structural change and higher educated labour in Indonesia.

PubMed

Pasay, N H

1990-12-01

This paper describes an impending shortage of higher-educated labor in Indonesia. Dynamic change is occurring in both Indonesia's population and economy. Its rapidly growing population demands annual national economic growth of 2.2% to avoid declining per capita output. Accordingly, investments have surged in banking and manufacturing industries as Indonesia undergoes structural change from an agricultural to service-based economy. Plagued by a majority of low productivity, elementary-level educated workers, increased productivity is called for to ensure continued development. As the age structural shift progresses, many of these workers will be absorbed in the services sector. Jobs exist requiring workers of all skill levels. This paper is mainly concerned, however, with higher-educated labor's failure to be oriented to the research and development required for sustained economic growth and development, and their entry into clerical positions potentially filled by less educated and less skilled labor. The services sector, particularly public services, is responsible for absorbing much of this labor. As professional, technical, and managerial capabilities and qualifications become increasingly needed in the near future as sector investments take effect, a shortage of higher-educated labor will become apparent. Policy makers are advised to anticipate these shortages and contemplate investments in human capital to facilitate a more smooth adjustment to structural change.

Compendium of ordinances for groundwater protection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-08-01

Groundwater is an extremely important resource in the Tennessee Valley. Nearly two-thirds of the Tennessee Valley's residents rely, at least in part, on groundwater supplies for drinking water. In rural areas, approximately ninety-five percent of residents rely on groundwater for domestic supplies. Population growth and economic development increase the volume and kinds of wastes requiring disposal which can lead to groundwater contamination. In addition to disposal which can lead to groundwater contamination. In addition to disposal problems associated with increases in conventional wastewater and solid waste, technological advancements in recent decades have resulted in new chemicals and increased usage inmore » agriculture, industry, and the home. Unfortunately, there has not been comparable progress in identifying the potential long-term effects of these chemicals, in managing them to prevent contamination of groundwater, or in developing treatment technologies for removing them from water once contamination has occurred. The challenge facing residence of the Tennessee Valley is to manage growth and economic and technological development in ways that will avoid polluting the groundwater resource. Once groundwater has been contaminated, cleanup is almost always very costly and is sometimes impractical or technically infeasible. Therefore, prevention of contamination -- not remedial treatment--is the key to continued availability of usable groundwater. This document discusses regulations to aid in this prevention.« less

Topological insulator film growth by molecular beam epitaxy: A review

DOE PAGES

Ginley, Theresa P.; Wang, Yong; Law, Stephanie

2016-11-23

In this article, we will review recent progress in the growth of topological insulator (TI) thin films by molecular beam epitaxy (MBE). The materials we focus on are the V 2-VI 3 family of TIs. These materials are ideally bulk insulating with surface states housing Dirac excitations which are spin-momentum locked. These surface states are interesting for fundamental physics studies (such as the search for Majorana fermions) as well as applications in spintronics and other fields. However, the majority of TI films and bulk crystals exhibit significant bulk conductivity, which obscures these states. In addition, many TI films have amore » high defect density. This review will discuss progress in reducing the bulk conductivity while increasing the crystal quality. We will describe in detail how growth parameters, substrate choice, and growth technique influence the resulting TI film properties for binary and ternary TIs. We then give an overview of progress in the growth of TI heterostructures. Furthermore, we close by discussing the bright future for TI film growth by MBE.« less

Transforming growth factor-β1 promotes breast cancer metastasis by downregulating miR-196a-3p expression.

PubMed

Chen, Yan; Huang, Shai; Wu, Bo; Fang, Jiankai; Zhu, Minsheng; Sun, Li; Zhang, Lifeng; Zhang, Yongsheng; Sun, Maomin; Guo, Lingling; Wang, Shouli

2017-07-25

Transforming growth factor-β1 is considered a key contributor to the progression of breast cancer. MicroRNAs are important factors in the development and progression of many malignancies. In the present study, upon studies of breast cancer cell lines and tissues, we showed that microRNA -196a-3p is decreased by transforming growth factor-β1 in breast cancer cells and associated with breast cancer progression. We identified neuropilin-2 as a target gene of microRNA -196a-3p and showed that it is regulated by transforming growth factor-β1. Moreover, transforming growth factor-β1-mediated inhibition of microRNA -196a-3p and activation of neuropilin-2were required for transforming growth factor-β1-induced migration and invasion of breast cancer cells. In addition, neuropilin-2 expression was suppressed in breast tumors, particularly in triple-negative breast cancers. Collectively, our findings strongly indicate that microRNA -196a-3p is a predictive biomarker of breast cancer metastasis and patient survival and a potential therapeutic target in metastatic breast cancer.

40 CFR 57.605 - Consent.

Code of Federal Regulations, 2011 CFR

2011-07-01

... such agency determines are needed to evaluate the technical or economic merits of the program; (c... discussions of progress, interpretation of data and results, and any other similar purposes as deemed...

78 FR 14361 - Proposal Review; Notice of Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-05

... awards. The review and evaluation may also include assessment of the progress of awarded proposals. The... confidential nature, including technical information; financial data, such as salaries; and personal...

78 FR 54686 - Proposal Review; Notice of Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-05

... awards. The review and evaluation may also include assessment of the progress of awarded proposals. The... confidential nature, including technical information; financial data, such as salaries; and personal...

Process modelling for space station experiments

NASA Technical Reports Server (NTRS)

Rosenberger, Franz; Alexander, J. Iwan D.

1988-01-01

The work performed during the first year 1 Oct. 1987 to 30 Sept. 1988 involved analyses of crystal growth from the melt and from solution. The particular melt growth technique under investigation is directional solidification by the Bridgman-Stockbarger method. Two types of solution growth systems are also being studied. One involves growth from solution in a closed container, the other concerns growth of protein crystals by the hanging drop method. Following discussions with Dr. R. J. Naumann of the Low Gravity Science Division at MSFC it was decided to tackle the analysis of crystal growth from the melt earlier than originally proposed. Rapid progress was made in this area. Work is on schedule and full calculations were underway for some time. Progress was also made in the formulation of the two solution growth models.

Personal Background Interview of Jim McBarron

NASA Technical Reports Server (NTRS)

McBarron, Jim; Wright, Rebecca

2012-01-01

Jim McBarron exhibits a wealth of knowledge gathered from more than 40 years of experience with NASA, EVA, and spacesuits. His biography, progression of work at NASA, impact on EVA and the U.S. spacesuit, and career accomplishments are of interest to many. Wright, from the JSC History Office, conducted a personal background interview with McBarron. This interview highlighted the influences and decision-making methods that impacted McBarron's technical and management contributions to the space program. Attendees gained insight on the external and internal NASA influences on career progression within the EVA and spacesuit, and the type of accomplishments and technical advances that committed individuals can make. He concluded the presentation with a question and answer period that included a brief discussion about close calls and Russian spacesuits.

Moses Lake Fishery Restoration Project; Factors Affecting the Recreational Fishery in Moses Lake Washington, Annual Report 2002-2003.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burgess, Dave

2003-11-01

This annual report is a precursor to the final technical report we will be writing the next contract period. Consequently, this report, covering the period between September 27, 2002, and September 26, 2003, represents a progress report towards the final technical report we anticipate completing by September 26, 2004. Sample analysis and field work have progressed well and we anticipate no further delays. There are 4 objectives: (1) To quantify secondary production Moses Lake; (2) To quantify the influence of predation on target fishes in Moses Lake; (3) To quantify mortality of selected fished in Moses Lake; and (4) Tomore » assess effects of habitat changes from shoreline development and carp on the fish community in Moses Lake.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ginley, Theresa P.; Wang, Yong; Law, Stephanie

In this article, we will review recent progress in the growth of topological insulator (TI) thin films by molecular beam epitaxy (MBE). The materials we focus on are the V 2-VI 3 family of TIs. These materials are ideally bulk insulating with surface states housing Dirac excitations which are spin-momentum locked. These surface states are interesting for fundamental physics studies (such as the search for Majorana fermions) as well as applications in spintronics and other fields. However, the majority of TI films and bulk crystals exhibit significant bulk conductivity, which obscures these states. In addition, many TI films have amore » high defect density. This review will discuss progress in reducing the bulk conductivity while increasing the crystal quality. We will describe in detail how growth parameters, substrate choice, and growth technique influence the resulting TI film properties for binary and ternary TIs. We then give an overview of progress in the growth of TI heterostructures. Furthermore, we close by discussing the bright future for TI film growth by MBE.« less

Learning Progressions as Evolving Tools in Joint Enterprises for Educational Improvement

ERIC Educational Resources Information Center

Penuel, William R.

2015-01-01

In their article, "Using Learning Progressions to Design Vertical Scales that Support Coherent Inferences about Student Growth," Briggs and Peck (this issue) argue that an important goal of assessment should be "to support coherent and actionable inferences of growth." They suggest that current approaches to test design rely on…

The Ecology of Technological Progress: How Symbiosis and Competition Affect the Growth of Technology Domains

ERIC Educational Resources Information Center

Carnabuci, Gianluca

2010-01-01

We show that the progress of technological knowledge is an inherently ecological process, wherein the growth rate of each technology domain depends on dynamics occurring in "other" technology domains. We identify two sources of ecological interdependence among technology domains. First, there are symbiotic interdependencies, implying…

YAP forms autocrine loops with the ERBB pathway to regulate ovarian cancer initiation and progression.

PubMed

He, C; Lv, X; Hua, G; Lele, S M; Remmenga, S; Dong, J; Davis, J S; Wang, C

2015-12-10

Mechanisms underlying ovarian cancer initiation and progression are unclear. Herein, we report that the Yes-associated protein (YAP), a major effector of the Hippo tumor suppressor pathway, interacts with ERBB signaling pathways to regulate the initiation and progression of ovarian cancer. Immunohistochemistry studies indicate that YAP expression is associated with poor clinical outcomes in patients. Overexpression or constitutive activation of YAP leads to transformation and tumorigenesis in human ovarian surface epithelial cells, and promotes growth of cancer cells in vivo and in vitro. YAP induces the expression of epidermal growth factor (EGF) receptors (EGFR, ERBB3) and production of EGF-like ligands (HBEGF, NRG1 and NRG2). HBEGF or NRG1, in turn, activates YAP and stimulates cancer cell growth. Knockdown of ERBB3 or HBEGF eliminates YAP effects on cell growth and transformation, whereas knockdown of YAP abrogates NRG1- and HBEGF-stimulated cell proliferation. Collectively, our study demonstrates the existence of HBEGF & NRGs/ERBBs/YAP/HBEGF & NRGs autocrine loop that controls ovarian cell tumorigenesis and cancer progression.

[Pathogenetic and Prognostic Role of Growth Factors in the Development of Chronic Heart Failure].

PubMed

Teplyakov, A T; Berezikova, E N; Shilov, S N; Efremova, A V; Pustovetova, M G; Popova, A A; Grakova, E V; Torim, Y Y; Safronov, I D; Andriyanova, A V

2017-10-01

To study the role of growth factors ((vascular endothelial growth factor (VEGF), platelet derived growth factor AB (PDGF-AB) and basic fibroblast growth factor (FGF-basic)) in the development and progression of chronic heart failure (CHF) in patients with ishcemic heart disease (IHD). We included in this study 94 patients with CHF. The control group comprised 32 persons. Blood serum levels of growth factors were determined at baseline and after 12 months of observation by enzyme-linked immunosorbent assay. VEGF, PDGF-AB and FGF-basic play an important role in the pathogenesis and progression of heart failure in patients with IHD, determining the increased risk of adverse cardiovascular events in this pathology. Serum activity of growth factors characterizes the severity and course of CHF: with disease progression levels of VEGF and FGF-basic decrease and PDGF-AB concentration increases. Initial low level of VEGF expression regardless of the sex of the patient's sex, significantly low level of FGF-basic and significantly high PDGF-AB in men characterizes unfavorable course of CHF. A correlation has been established between blood serum levels of VEGF, PDGF-AB and FGF-basic and severity and course of CHF.

Flat-plate solar array project. Volume 8: Project analysis and integration

NASA Technical Reports Server (NTRS)

Mcguire, P.; Henry, P.

1986-01-01

Project Analysis and Integration (PA&I) performed planning and integration activities to support management of the various Flat-Plate Solar Array (FSA) Project R&D activities. Technical and economic goals were established by PA&I for each R&D task within the project to coordinate the thrust toward the National Photovoltaic Program goals. A sophisticated computer modeling capability was developed to assess technical progress toward meeting the economic goals. These models included a manufacturing facility simulation, a photovoltaic power station simulation and a decision aid model incorporating uncertainty. This family of analysis tools was used to track the progress of the technology and to explore the effects of alternative technical paths. Numerous studies conducted by PA&I signaled the achievement of milestones or were the foundation of major FSA project and national program decisions. The most important PA&I activities during the project history are summarized. The PA&I planning function is discussed and how it relates to project direction and important analytical models developed by PA&I for its analytical and assessment activities are reviewed.

Alaska OCS social and economic studies program. Technical report Number 94. Diapir field Anchorage impacts analysis. Final technical report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1984-03-01

The purpose of the study is threefold: (1) to update earlier baseline descriptions of Anchorage region; (2) to revise the community impact-assessment methodology to be applied to the Anchorage region; and (3) to assess the community impacts on the Anchorage region through the year 2010 of a base-case growth forecast and of a scenario for production of 3.0 billion barrels of crude oil from the Diapir Field OCS Sale no.87. Some results of the study are that the Anchorage region, historically and currently, has demonstrated a very resilient capacity to accommodate rapid economic and population growth; and that State expendituremore » of petroleum revenues accounts for much of the region's recent growth.« less

Ongoing Progress in Spacecraft Controls

NASA Technical Reports Server (NTRS)

Ghosh, Dave (Editor)

1992-01-01

This publication is a collection of papers presented at the Mars Mission Research Center workshop on Ongoing Progress in Spacecraft Controls. The technical program addressed additional Mars mission control problems that currently exist in robotic missions in addition to human missions. Topics include control systems design in the presence of large time delays, fuel-optimal propulsive control, and adaptive control to handle a variety of unknown conditions.

Xenon Feed System Progress

DTIC Science & Technology

2006-01-01

From - To) 13-06-2006 Technical Paper 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER F04611-00-C-0055 Xenon Feed System Progress (Preprint) 5b. GRANT...propulsion xenon feed system for a flight technology demonstration program. Major accomplishments include: 1) Utilization of the Moog...successfully fed xenon to a 200 watt Hall Effect Thruster in a Technology Demonstration Program. The feed system has demonstrated throttling of xenon

Gas-heat-pump development

NASA Astrophysics Data System (ADS)

Creswick, F. A.

Incentives for the development of gas heat pumps are discussed. Technical progress made on several promising technologies was reviewed. The status of development of gas-engine-driven heat pumps, the absorption cycle for the near- and long-term gas heat pump systems, the Stirling engine, the small Rankine-cycle engines, and gas-turbine-driven heat pump systems were briefly reviewed. Progress in the US, Japan, and Europe is noted.

Examining the Technical Adequacy of Progress Monitoring Using Early Writing Curriculum-Based Measures

ERIC Educational Resources Information Center

Hampton, David D.; Lembke, Erica S.

2016-01-01

The purpose of this study was to examine 4 early writing measures used to monitor the early writing progress of 1st-grade students. We administered the measures to 23 1st-grade students biweekly for a total of 16 weeks. We obtained 3-min samples and conducted analyses for each 1-min increment. We scored samples using 2 different methods: correct…

USAARL Annual Progress Report Fiscal Year 2012

DTIC Science & Technology

2013-04-01

analyzed. A technical report is currently in progress. A research project entitled “Clinical Assessment of the Noise Immune Stethoscope ” evaluated the...noise immune stethoscope (NIS), a dual mode electronic and Doppler device, at Madigan Army Medical Center. Insight from the evaluations, data...Immune Stethoscope aboard a U.S. Navy Carrier. (Report No. 2012-02). Fort Rucker, AL: U.S. Army Aeromedical Research Laboratory. Gordon, E., & Reeves

State Test Score Trends through 2007-08, Part 6: Has Progress Been Made in Raising Achievement for English Language Learners?

ERIC Educational Resources Information Center

Chudowsky, Naomi; Chudowsky, Victor

2010-01-01

This report by the Center on Education Policy (CEP), an independent nonprofit organization, examines progress in raising achievement for English language learners. It also describes the factors that make it difficult to accurately assess what ELLs know and can do. The data for this analysis were collected by CEP with technical support from the…

A "Fear" Studies Perspective and Critique: Analyzing English and Stengel's Progressive Study of Fear and Learning in "Education Theory." Technical Paper No. 37

ERIC Educational Resources Information Center

Fisher, R. Michael

2011-01-01

The author critiques the progressive approach of two contemporary educational philosophers (English and Stengel) on the topic of fear and learning. Using a postmodern integral approach, this article examines the tendency of reductionism, individualism, and psychologism as part of a hegemonic liberalism and modernism in discourses on fear and…

Quantum Manybody Physics with Rydberg Polaritons

DTIC Science & Technology

2016-06-22

report, such as final, technical, interim, memorandum, master’s thesis, progress, quarterly, research , special, group study, etc. 3. DATES COVERED...for public release. Over the course of this grant, we have seen tremendous progress, both theoretically and experimentally , in our control of photonic...shown in multiple stages of construction at left and below, spans three optical tables in two rooms: One for the experimental control system

The role of spinal concave–convex biases in the progression of idiopathic scoliosis

PubMed Central

Driscoll, Mark; Moreau, Alain; Villemure, Isabelle; Parent, Stefan

2009-01-01

Inadequate understanding of risk factors involved in the progression of idiopathic scoliosis restrains initial treatment to observation until the deformity shows signs of significant aggravation. The purpose of this analysis is to explore whether the concave–convex biases associated with scoliosis (local degeneration of the intervertebral discs, nucleus migration, and local increase in trabecular bone-mineral density of vertebral bodies) may be identified as progressive risk factors. Finite element models of a 26° right thoracic scoliotic spine were constructed based on experimental and clinical observations that included growth dynamics governed by mechanical stimulus. Stress distribution over the vertebral growth plates, progression of Cobb angles, and vertebral wedging were explored in models with and without the biases of concave–convex properties. The inclusion of the bias of concave–convex properties within the model both augmented the asymmetrical loading of the vertebral growth plates by up to 37% and further amplified the progression of Cobb angles and vertebral wedging by as much as 5.9° and 0.8°, respectively. Concave–convex biases are factors that influence the progression of scoliotic curves. Quantifying these parameters in a patient with scoliosis may further provide a better clinical assessment of the risk of progression. PMID:19130096

Energy as a Natural Resource

ERIC Educational Resources Information Center

Seeger, Raymond J.

1971-01-01

Briefly discusses energy consumption per capita as an index of technical progress, a historical review of concepts related to energy conservation, energy conversion, natural sources, man-made sources, and social implications. (PR)

Progressive Educators Must Lead, Not Follow.

ERIC Educational Resources Information Center

Hairston, George

2000-01-01

While technical training is crucial in an engineer's education, so too is the study of economics and business. Students need experience in business principles to succeed in today's business environment. (MM)

A Computer Simulation of Bacterial Growth During Food-Processing

DTIC Science & Technology

1974-11-01

1 AD A TECHNICAL REPORT A COMPUTER SIMULATION OF BACTERIAL GROWTH DURING FOOD PROCESSING =r= by Edward W. Ross, Jr. Approved for public...COMPUTER SIMULATION OF BACTERIAL GROWTH DURING FOOD - PROCESSING Edward W. Ross, Jr. Army Natick Laboratories Natick, Massachusetts Novembe...CATALOG NUMBER 4. TITLE fand SubtKUJ "A Computer Sinulatlon of Bacterial Growth During Food - Processing " 5. TYPE OF REPORT A PERIOD COVERED 6

Technical change in US industry: A cross-industry analysis

NASA Technical Reports Server (NTRS)

Nelson, R. R. (Editor)

1981-01-01

The nature of the public policies which have influenced the pace and pattern of technical progress in a number of American industries is studied with the view of assessing the broad effects of these policies. The industries studied are agriculture, pharmaceuticals, semiconductors, computers, civil aircraft, automobiles and residential construction. The policies considered include research and development funding as well as government procurement, education, information dissemination, patent protection, licensing, regulations, and anti-trust policies.

The Value Added National Project. Technical Report: Primary 4. Value-Added Key Stage 1 to Key Stage 2.

ERIC Educational Resources Information Center

Tymms, Peter

This is the fourth in a series of technical reports that have dealt with issues surrounding the possibility of national value-added systems for primary schools in England. The main focus has been on the relative progress made by students between the ends of Key Stage 1 (KS1) and Key Stage 2 (KS2). The analysis has indicated that the strength of…

Silicon carbide - Progress in crystal growth

NASA Technical Reports Server (NTRS)

Powell, J. Anthony

1987-01-01

Recent progress in the development of two processes for producing large-area high-quality single crystals of SiC is described: (1) a modified Lely process for the growth of the alpha polytypes (e.g., 6H SiC) initially developed by Tairov and Tsvetkov (1978, 1981) and Ziegler et al. (1983), and (2) a process for the epitaxial growth of the beta polytype on single-crystal silicon or other substrates. Growth of large-area cubic SiC on Si is described together with growth of defect-free beta-SiC films on alpha-6H SiC crystals and TiC lattice. Semiconducting qualities of silicon carbide crystals grown by various techniques are discussed.

Predicting reading outcomes with progress monitoring slopes among middle grade students

PubMed Central

Tolar, Tammy D.; Barth, Amy E.; Fletcher, Jack M.; Francis, David J.; Vaughn, Sharon

2013-01-01

Effective implementation of response-to-intervention (RTI) frameworks depends on efficient tools for monitoring progress. Evaluations of growth (i.e., slope) may be less efficient than evaluations of status at a single time point, especially if slopes do not add to predictions of outcomes over status. We examined progress monitoring slope validity for predicting reading outcomes among middle school students by evaluating latent growth models for different progress monitoring measure-outcome combinations. We used multi-group modeling to evaluate the effects of reading ability, reading intervention, and progress monitoring administration condition on slope validity. Slope validity was greatest when progress monitoring was aligned with the outcome (i.e., word reading fluency slope was used to predict fluency outcomes in contrast to comprehension outcomes), but effects varied across administration conditions (viz., repeated reading of familiar vs. novel passages). Unless the progress monitoring measure is highly aligned with outcome, slope may be an inefficient method for evaluating progress in an RTI context. PMID:24659899

NBIC-Convergence of Machinery and Basic Technologies as the Ecological Factor of Wellbeing

NASA Astrophysics Data System (ADS)

Zhironkin, S. A.; Kolotov, K. A.; Genin, A. E.; Agafonov, F. V.; Kovalevsky, S. A.

2017-01-01

The development of science and technology in the XXI century is on the way of the extensive use of natural resources. As a result, the scientific and technical progress does not initiate the reduction of environmental damage but encourages its cumulative growth. So the environmental problems have become a serious threat to social wellbeing of all mankind. The development of the core technologies doesn’t allow creating the situation in which the new knowledge would generate positive changes in the environment. Therefore, among the issues that define the future of advanced environmental technologies, and potentially significant for the understanding of the humanities, there is the phenomenon of technological convergence and, in particular, the predicted convergence of the nano-, bio-, information and cognitive technologies (NBIC). The consequence of NBIC-convergence may be the transformation of the humanity into a single global mind, which can be linked into a solid set of technologies, establishing united standards for social wellbeing and environmental technologies.

[Healthcare expenditures growth: the red herring of demographic ageing?].

PubMed

Tenand, Marianne

2016-02-01

Demographic ageing is often deemed responsible for the massive increase in health expenditures experienced by developed countries. As the elderly consume more medical care than the rest of the population, how could the increase in the share of the 60 + not lead to a marked expansion of healthcare public and private budgets? Despite its apparent logics, such reasoning is fallacious: it ignores that medical care consumption depends on many factors beyond age, which have tremendously evolved in the last decades and may change again in the future. Based on French stylized facts, this article provides an overview of the international literature that aimed at disentangling the respective roles of population ageing and of the non-demographic factors in explaining the dynamics of health expenditures. Paradoxically, technical medical progress has been a major contributor to the increase of healthcare spending. Results from economics research lead to qualify the impact of demographic trends and call for more attention to the public policies decisions that shape healthcare systems. © 2016 médecine/sciences – Inserm.

Analysis of scanner data for crop inventories

NASA Technical Reports Server (NTRS)

Horvath, R. (Principal Investigator); Cicone, R. C.; Kauth, R. J.; Malila, W. A.

1981-01-01

Progress and technical issues are reported in the development of corn/soybeans area estimation procedures for use on data from South America, with particular emphasis on Argentina. Aspects related to the supporting research section of the AgRISTARS Project discussed include: (1) multisegment corn/soybean estimation; (2) through the season separability of corn and soybeans within the U.S. corn belt; (3) TTS estimation; (4) insights derived from the baseline corn and soybean procedure; (5) small fields research; and (6) simulating the spectral appearance of wheat as a function of its growth and development. To assist the foreign commodity production forecasting, the performance of the baseline corn/soybean procedure was analyzed and the procedure modified. Fundamental limitations were found in the existing guidelines for discriminating these two crops. The temporal and spectral characteristics of corn and soybeans must be determined because other crops grow with them in Argentina. The state of software technology is assessed and the use of profile techniques for estimation is considered.

Possible role of hemichannels in cancer

PubMed Central

Schalper, Kurt A.; Carvajal-Hausdorf, Daniel; Oyarzo, Mauricio P.

2014-01-01

In humans, connexins (Cxs) and pannexins (Panxs) are the building blocks of hemichannels. These proteins are frequently altered in neoplastic cells and have traditionally been considered as tumor suppressors. Alteration of Cxs and Panxs in cancer cells can be due to genetic, epigenetic and post-transcriptional/post-translational events. Activated hemichannels mediate the diffusional membrane transport of ions and small signaling molecules. In the last decade hemichannels have been shown to participate in diverse cell processes including the modulation of cell proliferation and survival. However, their possible role in tumor growth and expansion remains largely unexplored. Herein, we hypothesize about the possible role of hemichannels in carcinogenesis and tumor progression. To support this theory, we summarize the evidence regarding the involvement of hemichannels in cell proliferation and migration, as well as their possible role in the anti-tumor immune responses. In addition, we discuss the evidence linking hemichannels with cancer in diverse models and comment on the current technical limitations for their study. PMID:25018732

Quantifying the Ease of Scientific Discovery

PubMed Central

Arbesman, Samuel

2012-01-01

It has long been known that scientific output proceeds on an exponential increase, or more properly, a logistic growth curve. The interplay between effort and discovery is clear, and the nature of the functional form has been thought to be due to many changes in the scientific process over time. Here I show a quantitative method for examining the ease of scientific progress, another necessary component in understanding scientific discovery. Using examples from three different scientific disciplines – mammalian species, chemical elements, and minor planets – I find the ease of discovery to conform to an exponential decay. In addition, I show how the pace of scientific discovery can be best understood as the outcome of both scientific output and ease of discovery. A quantitative study of the ease of scientific discovery in the aggregate, such as done here, has the potential to provide a great deal of insight into both the nature of future discoveries and the technical processes behind discoveries in science. PMID:22328796

Quantifying the Ease of Scientific Discovery.

PubMed

Arbesman, Samuel

2011-02-01

It has long been known that scientific output proceeds on an exponential increase, or more properly, a logistic growth curve. The interplay between effort and discovery is clear, and the nature of the functional form has been thought to be due to many changes in the scientific process over time. Here I show a quantitative method for examining the ease of scientific progress, another necessary component in understanding scientific discovery. Using examples from three different scientific disciplines - mammalian species, chemical elements, and minor planets - I find the ease of discovery to conform to an exponential decay. In addition, I show how the pace of scientific discovery can be best understood as the outcome of both scientific output and ease of discovery. A quantitative study of the ease of scientific discovery in the aggregate, such as done here, has the potential to provide a great deal of insight into both the nature of future discoveries and the technical processes behind discoveries in science.

48 CFR 919.7011 - Developmental assistance.

Code of Federal Regulations, 2011 CFR

2011-10-01

...) Engineering and other technical assistance; (3) Noncompetitive award of subcontracts under DOE or other... activities; (5) Progress payments based on costs; (6) Rent-free use of facilities and/or equipment owned or...

Research progress on disease data bank and DATACON systems

NASA Technical Reports Server (NTRS)

1973-01-01

Developments and specific statistics for this reporting period are presented. The administration, community activities, funding, personnel, marketing and public relations, technical operations, information systems, and technology transfer are discussed.

Online Career and Technical Education in the Community College

ERIC Educational Resources Information Center

Garza Mitchell, Regina L.

2017-01-01

Very little empirical research has been conducted about online career and technical education (CTE). Despite the continuing enrollment growth in online education (Lokken, 2016) and the national emphasis on CTE as a means of boosting the economy (D'Amico, Morgan, Katsinas, & Friedel, 2014), relatively little is understood about the scope and…

Employment Shifts in the Technical and Further Education Workforce in Victoria.

ERIC Educational Resources Information Center

Shah, Chandra

2003-01-01

Analyzes changes in Technical and Further Education (TAFE) work force in Victoria, Australia, that occurred during the period 1993-98. Main changes include increased participation of women, significant growth in part-time employment, decline in full-time (mainly male) employment, and an increased use of seasonal teachers. (Includes 10 figures and…

Building Turnaround Capacity for Urban School Improvement: The Role of Adaptive Leadership and Defined Autonomy

ERIC Educational Resources Information Center

Conrad, Jill K.

2013-01-01

This dissertation examines the levels of and relationships between technical leadership, adaptive leadership, and defined autonomy among Denver school leaders along with their combined effects on school growth gains over time. Thirty principals provided complete responses to an online survey that included existing scales for technical leadership,…

A Strategic Plan for Texas State Technical Institute.

ERIC Educational Resources Information Center

Texas State Technical Inst., Waco.

Following two decades of growth, both enrollment and funding at the Texas State Technical Institute (TSTI) have declined sharply over the last 5 years. In April 1989, the TSTI initiated a strategic planning process incorporating a strategy based on meeting a clearly recognized and understood public need that is within the role, scope, and mission…

Engineering Programs of Tomorrow: The Role of Agricultural Engineering.

ERIC Educational Resources Information Center

Edwards, Donald M.

Due to rapid growth of societal and technological endeavors, engineers of the future will require greater technical competence. At the same time, engineering will become more people oriented with greater emphasis placed on people input into decision making. As a result, engineering education must not only provide improved technical education but…

Technical and Vocational Education and Training (TVET): Understanding the Nigerian Experience

ERIC Educational Resources Information Center

Dike, Victor Ebipuruonwu

2013-01-01

The descriptive mixed-methods study explores and describes the challenges and prospects of the growth and development of technical and vocational education and training (TVET) schools and science-based technology education in Nigeria. It is not understood how Nigerians in the United States perceive the impacts of governmental policies on education…

A State of Growth

ERIC Educational Resources Information Center

Gibbs, Hope J.

2005-01-01

In Georgia, the technical college system is flourishing and offers the Peachtree State's students a number of career opportunities that are ripe for the picking. Georgia has invested more than one billion dollars in its technical college system. The investment was well worth it, as thousands of students were drawn to the newly built and modernized…

Geotechnical support and topical studies for nuclear waste geologic repositories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1989-01-01

The present report lists the technical reviews and comments made during the fiscal year 1988 and summarizes the technical progress of the topical studies. In the area of technical assistance, there were numerous activities detailed in the next section. These included 24 geotechnical support activities, including reviews of 6 Study Plans (SP) and participation in 6 SP Review Workshops, review of one whole document Site Characterization Plan (SCP) and participation in the Assembled Document SCP Review Workshops by 6 LBL reviewers; the hosting of a DOE program review, the rewriting of the project statement of work, 2 trips to technicalmore » and planning meetings; preparation of proposed work statements for two new topics for DOE, and 5 instances of technical assistance to DOE. These activities are described in a Table in the following section entitled Geoscience Technical Support for Nuclear Waste Geologic Repositories.''« less

Antibody-Mediated Targeting of Alpha PDGF Receptor to Inhibit the Progression of Skeletal Micro-Metastases

DTIC Science & Technology

2012-10-01

8217 Affiliatio athology an e, Philadelp ponding Au ysiology, D MS 488, P 2-2299; E-m .1158/1078- American A ancer Respose : Platelet-derived growth factor...their metastatic growth. The resulting increase in tu- ass will recruit and activate a progressively higher er of osteoclasts, thereby generating a self

Connective tissue growth factor (CTGF) and cancer progression.

PubMed

Chu, Chia-Yu; Chang, Cheng-Chi; Prakash, Ekambaranellore; Kuo, Min-Liang

2008-11-01

Connective tissue growth factor (CTGF) is a member of the CCN family of secreted, matrix-associated proteins encoded by immediate early genes that play various roles in angiogenesis and tumor growth. CCN family proteins share uniform modular structure which mediates various cellular functions such as regulation of cell division, chemotaxis, apoptosis, adhesion, motility, angiogenesis, neoplastic transformation, and ion transport. Recently, CTGF expression has been shown to be associated with tumor development and progression. There is growing body of evidence that CTGF may regulate cancer cell migration, invasion, angiogenesis, and anoikis. In this review, we will highlight the influence of CTGF expression on the biological behavior and progression of various cancer cells, as well as its regulation on various types of protein signals and their mechanisms.

Creating Safe Growth Strategies for the San Francisco Bay Area

EPA Pesticide Factsheets

Report from a technical assistance project with the Association of Bay Area Governments to develop strategies to ensure that growth in the region is resilient to hazards such as earthquakes and sea level rise, but also affordable and transit accessible.

The Mathematical Education of Engineers.

ERIC Educational Resources Information Center

Gnedenko, B. V.; Khalil, Z.

1979-01-01

Several general aspects are discussed. These include the role of mathematics in scientific and technical progress, some deficiencies in training, the role of mathematics in engineering faculties, and methods of improving mathematical training. (MP)

Publications of the Jet Propulsion Laboratory 1976

NASA Technical Reports Server (NTRS)

1977-01-01

The formalized technical reporting, released January through December 1975, that resulted from scientific and engineering work performed, or managed, by the Jet Propulsion Laboratory is described and indexed. The following classes of publications are included: (1) technical reports; (2) technical memorandums; (3) articles from bi-monthly Deep Space Network (DSN) progress report; (4) special publications; and (5) articles published in the open literature. The publications are indexed by: (1) author, (2) subject, and (3) publication type and number. A descriptive entry appears under the name of each author of each publication; an abstract is included with the entry for the primary (first-listed) author. Unless designated otherwise, all publications listed are unclassified.

Building Stronger State Energy Partnerships with the U.S. Department of Energy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marks, Kate

2011-09-30

This final technical report details the results of total work efforts and progress made from October 2007 – September 2011 under the National Association of State Energy Officials (NASEO) cooperative agreement DE-FC26-07NT43264, Building Stronger State Energy Partnerships with the U.S. Department of Energy. Major topical project areas in this final report include work efforts in the following areas: Energy Assurance and Critical Infrastructure, State and Regional Technical Assistance, Regional Initiative, Regional Coordination and Technical Assistance, and International Activities in China. All required deliverables have been provided to the National Energy Technology Laboratory and DOE program officials.

Advanced light source: Compendium of user abstracts and technical reports,1993-1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

1997-04-01

This compendium contains abstracts written by users summarizing research completed or in progress from 1993-1996, ALS technical reports describing ongoing efforts related to improvement in machine operations and research and development projects, and information on ALS beamlines planned through 1998. Two tables of contents organize the user abstracts by beamline and by area of research, and an author index makes abstracts accessible by author and by principal investigator. Technical details for each beamline including whom to contact for additional information can be found in the beamline information section. Separate abstracts have been indexed into the database for contributions to thismore » compendium.« less

Physical phenomena related to crystal growth in the space environment

NASA Technical Reports Server (NTRS)

Chu, T. L.

1973-01-01

The mechanism of crystal growth which may be affected by the space environment was studied. Conclusions as to the relative technical and scientific advantages of crystal growth in space over earth bound growth, without regard to economic advantage, were deduced. It was concluded that the crucibleless technique will most directly demonstrate the unique effects of the greatly reduced gravity in the space environment. Several experiments, including crucibleless crystal growth using solar energy and determination of diffusion coefficients of common dopants in liquid silicon were recommended.

Fluorescent and high intensity discharge lamp use in chambers and greenhouses

NASA Technical Reports Server (NTRS)

Langhans, Robert W.

1994-01-01

Fluorescent and High Intensity Discharge lamps have opened up great opportunities for researchers to study plant growth under controlled environment conditions and for commercial growers to increase plant production during low/light periods. Specific technical qualities of fluorescent and HID lamps have been critically reviewed. I will direct my remarks to fluorescent and high intensity discharge (HID) lamps in growth chambers, growth rooms, and greenhouses. I will discuss the advantages and disadvantages of using each lamp in growth chambers, growth rooms and greenhouses.

Contribution of population growth to per capita income and sectoral output growth in Japan, 1880-1970.

PubMed

Yamaguchi, M; Kennedy, G

1984-09-01

The authors measured the positive and negative contributions of population and labor force growth to the growth of per capita income and sectoral output in Japan in the 1880-1970 period. A 2-sector growth accounting model that treats population and labor growth as separate variables was used. 3 alternative methods were used: the Residual method, the Verdoorn method, and the factor augmenting rate method. The total contribution of population cum labor growth to per capita income growth tended to be negative in the 1880-1930 period and positive in the 1930-40 and 1950-70. Over the 1880-1970 period as a whole, population cum labor growth made a positive contribution to per capita income growth under the Residual method (0.35%/year), the factor augmenting rate method (0.29%/year), and the Verdoorn method (0.01%/year). In addition, population cum labor growth contributed positively to sectoral output growth. The average contribution to agricultural output growth ranged from 1.03% (Verdoorn) - 1.46%/year (factor augmenting rate), while the average contribution to nonagricultural output growth ranged from 1.22% (Verdoorn) - 1.60%/year (Residual). Although these results are dependent on the model used, the fact that all 3 methods yielded consistent results suggests that population cum labor growth did make a positive contribution to per capita income and sectoral output growth in Japan. These findings imply that in economies where the rate of technical change in agricultural and nonagricultural sectors exceeds population growth, policies that reduce agricultural elasticities may be preferable; on the other hand, policies that reduce agricultural elasticities are to be avoided in economies with low rates of technical change. Moreover, in the early stages of economic development, policies that increase agricultural income and price elasticities should be considered.

Optical Gripper

NASA Astrophysics Data System (ADS)

Jalba, C. K.; Muminovic, A.; Epple, S.; Barz, C.; Nasui, V.

2017-05-01

With increasing automation, many work processes become more and more complex. Most technical products can no longer be developed and manufactured by a single department. They are often the product of different divisions and require cooperation from different specialist areas. For example, in the Western world, a simple coffee maker is no longer so much in demand. If the buyer has the possibility to choose between a simple coffee maker and a coffee machine with very complex functions, the choice will probably fall to the more complex variant. Technical progress also applies to other technical products, such as grippers and manipulators. In this paper, it is shown how grasping processes can be redefined and developed with interdisciplinary technical approaches. Both conventional and latest developments in mechanical engineering, production technology, mechatronics and sensor technology will be considered.

Imposing limits on autonomous systems.

PubMed

Hancock, P A

2017-02-01

Our present era is witnessing the genesis of a sea-change in the way that advanced technologies operate. Amongst this burgeoning wave of untrammelled automation there is now beginning to arise a cadre of ever-more independent, autonomous systems. The degree of interaction between these latter systems with any form of human controller is becoming progressively more diminished and remote; and this perhaps necessarily so. Here, I advocate for human-centred and human favouring constraints to be designed, programmed, promulgated and imposed upon these nascent forms of independent entity. I am not sanguine about the collective response of modern society to this call. Nevertheless, the warning must be voiced and the issue debated, especially among those who most look to mediate between people and technology. Practitioner Summary: Practitioners are witnessing the penetration of progressively more independent technical orthotics into virtually all systems' operations. This work enjoins them to advocate for sentient, rational and mindful human-centred approaches towards such innovations. Practitioners need to place user-centred concerns above either the technical or the financial imperatives which motivate this line of progress.

Symptomatic thoracic spinal cord herniation: case series and technical report.

PubMed

Hawasli, Ammar H; Ray, Wilson Z; Wright, Neill M

2014-09-01

Idiopathic spinal cord herniation (ISCH) is an uncommon condition located predominantly in the thoracic spine and often associated with a remote history of a major traumatic injury. ISCH has an incompletely described presentation and unknown etiology. There is no consensus on the treatment algorithm and surgical technique, and there are few data on clinical outcomes. In this case series and technical report, we describe the atypical myelopathy presentation, remote history of traumatic injury, radiographic progression, treatment, and outcomes of 5 patients treated at Washington University for symptomatic ISCH. A video showing surgical repair is presented. In contrast to classic compressive myelopathy symptomatology, ISCH patients presented with an atypical myelopathy, characterized by asymmetric motor and sensory deficits and early-onset urinary incontinence. Clinical deterioration correlated with progressive spinal cord displacement and herniation observed on yearly spinal imaging in a patient imaged serially because of multiple sclerosis. Finally, compared with compressive myelopathy in the thoracic spine, surgical treatment of ISCH led to rapid improvement despite a long duration of symptoms. Symptomatic ISCH presents with atypical myelopathy and slow temporal progression and can be successfully managed with surgical repair.

Progress and future direction for the interim safe storage and disposal of Hanford high-level waste

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kinzer, J.E.; Wodrich, D.D.; Bacon, R.F.

This paper describes the progress made at the largest environmental cleanup program in the United States. Substantial advances in methods to start interim safe storage of Hanford Site high-level wastes, waste characterization to support both safety- and disposal-related information needs, and proceeding with cost-effective disposal by the U.S. Department of Energy (DOE) and its Hanford Site contractors, have been realized. Challenges facing the Tank Waste Remediation System (TWRS) Program, which is charged with the dual and parallel missions of interim safe storage and disposal of the high-level tank waste stored at the Hanford Site, are described. In these times ofmore » budget austerity, implementing an ongoing program that combines technical excellence and cost effectiveness is the near-term challenge. The technical initiatives and progress described in this paper are made more cost effective by DOE`s focus on work force productivity improvement, reduction of overhead costs, and reduction, integration and simplification of DOE regulations and operations requirements to more closely model those used in the private sector.« less

CBM Maze-Scores as Indicators of Reading Level and Growth for Seventh-Grade Students

ERIC Educational Resources Information Center

Chung, Siuman; Espin, Christine A.; Stevenson, Claire E.

2018-01-01

The technical adequacy of CBM maze-scores as indicators of reading level and growth for seventh-grade secondary-school students was examined. Participants were 452 Dutch students who completed weekly maze measures over a period of 23 weeks. Criterion measures were school level, dyslexia status, scores and growth on a standardized reading test.…

Instructional Film Research Program; Period: 1 March to 30 June 1949. Progress Report Number 11-12.

ERIC Educational Resources Information Center

Pennsylvania State Univ., University Park. Coll. of Education.

A combination of a progress report and a technical report, this paper should prove useful as an aid in planning future research, and should prove generally useful to those interested in communication processes by means of sound films, as well as to those who work in the areas of radio and television. Effectively there are two halves to the paper.…

Using the National Assessment of Educational Progress To Confirm State Test Results. A Report of the Ad Hoc Committee on Confirming Test Results.

ERIC Educational Resources Information Center

National Assessment Governing Board, Washington, DC.

The National Assessment Governing Board has recognized the need to study associated policy and technical issues to ensure that the National Assessment of Educational Progress (NAEP) is ready to do the best job possible if called on to confirm the results of state achievement testing under the No Child Left Behind Act. This report describes the…

Solar hot water space heating system. Technical progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Van Dam, T

1979-08-13

A retrofit solar heating system was installed on Madison Hall at Jordan College, Cedar Springs, Michigan. The system provides heating and domestic water preheating for a campus dormitory. Freeze protection is provided by a draindown system. The building and solar system, construction progress, and design changes are described. Included in appendices are: condensate trap design, structural analysis, pictures of installation, operating instructions, maintenance instructions, and as-built drawings. (MHR)

U.C. Davis high energy particle physics research: Technical progress report -- 1990

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

Summaries of progress made for this period is given for each of the following areas: (1) Task A--Experiment, H1 detector at DESY; (2) Task C--Experiment, AMY detector at KEK; (3) Task D--Experiment, fixed target detectors at Fermilab; (4) Task F--Experiment, PEP detector at SLAC and pixel detector; (5) Task B--Theory, particle physics; and (6) Task E--Theory, particle physics.

High beta and second stability region transport and stability analysis: Technical progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hughes, M.H.; Phillips, M.W.

1995-03-01

This report summarizes MHD equilibrium and stability studies carried out at Northrop Grumman`s Advanced Technology and Development Center during the 12 month period starting March 1, 1994. Progress is reported in both ideal and resistive MHD modeling of TFTR plasmas. The development of codes to calculate the significant effects of highly anisotropic pressure distributions is discussed along with results from this model.

NASA-UVA light aerospace alloy and structures technology program (LA2ST)

NASA Technical Reports Server (NTRS)

Gangloff, Richard P.; Starke, Edger A., Jr.

1996-01-01

This progress report covers achievements made between January 1 and June 30, 1966 on the NASA-UVA Light Aerospace Alloy and Structures Technology (LA2ST) Program. The objective of the LA2ST Program is to conduct interdisciplinary graduate student research on the performance of next generation, light-weight aerospace alloys, composites and thermal gradient structures in collaboration with NASA-Langley researchers. Specific technical objectives are presented for each research project. . The accomplishments presented in this report are: (1) Mechanical and Environmental Degradation Mechanisms in Advanced Light Metals, (2) Aerospace Materials Science, and (3) Mechanics of Materials for Light Aerospace Structures. Collective accomplishments between January and June of 1996 include: 4 journal or proceedings publications, 1 NASA progress report, 4 presentations at national technical meetings, and 2 PhD dissertations published.

Spray forming -- Aluminum: Third annual report (Phase 2). Technical progress -- Summary

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kozarek, R.L.

1998-04-20

Commercial production of aluminum sheet and plate by spray atomization and deposition is a potentially attractive manufacturing alternative to conventional ingot metallurgy/hot-milling and to continuous casting processes because of reduced energy requirements and reduced cost. To realize the full potential of the technology, the Aluminum Company of America (Alcoa), under contract by the US Department of Energy, is investigating currently available state-of-the-art atomization devices to develop nozzle design concepts whose spray characteristics are tailored for continuous sheet production. This third technical progress report will summarize research and development work conducted during the period 1997 October through 1998 March. Included aremore » the latest optimization work on the Alcoa III nozzle, results of spray forming runs with 6111 aluminum alloy and preliminary rolling trials of 6111 deposits.« less

A history of ventricular neuroendoscopy.

PubMed

Decq, Philippe; Schroeder, Henry W S; Fritsch, Michael; Cappabianca, Paolo

2013-02-01

To describe the history of neuroendoscopy through the history of the major neurosurgeons who worked and published in the field. All relevant data described in publications before 1980 about the history of neuroendoscopy and found through OVID MEDLINE searches and related references are reported. Contributions of 14 neurosurgeons who were pioneers in neuroendoscopy are described in chronologic order: Lespinasse, Dandy, Payr, Mixter, Fay, Grant, Volkmann, Putnam, Dereymacker, Scarff, Feld, Guiot, Fukushima, and Griffith. An historical review of ventricular neuroendoscopy remains by essence incomplete. Medical technical progress proceeds by leaps and bounds, related to the ingenuity of surgeons able to understand rapidly the value of a technical change to improve their surgical procedure. The ability to remain attentive to patients and evolving pathologies as well as the evolution of modern technology is required to make further progress in neuroendoscopy. Copyright © 2013 Elsevier Inc. All rights reserved.

Responsive copolymers for enhanced petroleum recovery. Quarterly technical progress report, June 23--September 21, 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCormick, C.; Hester, R.

Summaries are given on the technical progress on three tasks of this project. Monomer and polymer synthesis discusses the preparation of 1(7-aminoheptyloxymethyl)naphthalene and poly(maleic anhydride-alt-ethyl vinyl ether). Task 2, Characterization of molecular structure, discusses terpolymer solution preparation, UV analysis, fluorescence analysis, low angle laser light scattering, and viscometry. The paper discusses the effects of hydrophobic groups, the effect of pH, the effect of electrolyte addition, and photophysical studies. Task 3, Solution properties, describes the factorial experimental design for characterizing polymer solutions by light scattering, the light scattering test model, orthogonal factorial test design, linear regression in coded space, confidence levelmore » for coded space test mode coefficients, coefficients of the real space test model, and surface analysis of the model equations.« less

Chemical and biological nonproliferation program. FY99 annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

2000-03-01

This document is the first of what will become an annual report documenting the progress made by the Chemical and Biological Nonproliferation Program (CBNP). It is intended to be a summary of the program's activities that will be of interest to both policy and technical audiences. This report and the annual CBNP Summer Review Meeting are important vehicles for communication with the broader chemical and biological defense and nonproliferation communities. The Chemical and Biological Nonproliferation Program Strategic Plan is also available and provides additional detail on the program's context and goals. The body of the report consists of an overviewmore » of the program's philosophy, goals and recent progress in the major program areas. In addition, an appendix is provided with more detailed project summaries that will be of interest to the technical community.« less

The Background-Limited Infrared Submillimeter Spectrograph (BLISS) for SPICA

NASA Astrophysics Data System (ADS)

Bradford, Charles; BLISS-SPICA Study Team

2011-05-01

The far-IR waveband carries half of the photon energy ever produced in galaxies and quasars, evidence of the major role of dust-obscured star formation and black-hole growth had in bringing about the modern Universe. The bulk of this dust-obscured activity appears to have occurred in the first half of the Universe's history (z>1). We are developing the Background-Limited Infrared-Submillimeter Spectrograph (BLISS) to capitalize on SPICA's cold telescope and provide a breakthrough far-IR spectroscopy capability. BLISS-SPICA is 6 orders of magnitude faster than the spectrometers on Herschel and SOFIA in obtaining full-band spectra, and offer the capability to overcome the spatial confusion limit with spectroscopic capability. BLISS-SPICA will observe dust-obscured galaxies at all epochs back to the first billion years after the Big Bang (redshift 6), thereby probing the complete history of dust-obscured star formation and black-hole growth. It will also be extremely powerful for studying ice-giant planet formation in protoplanetary disks, with its sensitivity to very small amounts of gas. Given its enormous potential, BLISS has been recommended by Astro2010 as an example US contribution to SPICA. BLISS covers the 38-433 micron range in six grating-spectrometer bands, with two simultaneous sky positions. The baseline detector package is 4224 silicon-nitride micro-mesh leg-isolated bolometers with superconducting transition-edge-sensed (TES) thermistors, read out with a cryogenic time-domain multiplexer. All spectrometers and detector arrays are cooled to 50mK for optimal sensitivity. All technical elements of BLISS have heritage in mature scientific instruments, and many have flown. We present the science case for BLISS, as well as our progress in the key technical aspects: 1) detector and readout performance demonstration, 2) opto-mechanical instrument configuration, and 3) sub-K cooling and cryogenic system approach.

Research and Technology Operating Plan Summary: Fiscal Year 1973 Research and Technology Program

NASA Technical Reports Server (NTRS)

1972-01-01

Abstracts are presented of each of the Research and Technology Operating Plans (RTOP) used for management review and control of research currently in progress throughout NASA. This RTOP Summary is designed to facilitate communication and coordination among concerned technical personnel in government, industry, and universities. The summary is arranged in five sections consisting of citations and abstracts of the RTOPs and subject, technical monitor, responsible NASA organization, and RTOP number indexes.

Decarbonizing the international shipping industry: Solutions and policy recommendations.

PubMed

Wan, Zheng; El Makhloufi, Abdel; Chen, Yang; Tang, Jiayuan

2018-01-01

Ship-source greenhouse gas (GHG) emissions could increase by up to 250% by 2050 from their 2012 levels, owing to increasing global freight volumes. Binding international legal agreements to regulate GHGs, however, are lacking as technical solutions remain expensive, and crucial industrial support is absent. In 2003, the International Maritime Organization adopted Resolution A.963 (23) to regulate shipping CO 2 emissions via technical, operational, and market-based routes. However, progress has been slow and uncertain; there is no concrete emission reduction target or definitive action plan. Yet, a full-fledged roadmap may not even emerge until 2023. In this policy analysis, we revisit the progress of technical, operational, and market-based routes and the associated controversies. We argue that 1) a performance-based index, though good-intentioned, has loopholes affecting meaningful CO 2 emission reductions driven by technical advancements; 2) using slow steaming to cut energy consumption stands out among all operational solutions thanks to its immediate and obvious results, but with the already slow speed in practice, this single source has limited emission reduction potential; 3) without a technology-savvy shipping industry, a market-based approach is essentially needed to address the environmental impact. To give shipping a 50:50 chance for contributing fairly and proportionately to keep global warming below 2°C, deep emission reductions should occur soon. Copyright © 2017 Elsevier Ltd. All rights reserved.

Thin EFG octagons

NASA Astrophysics Data System (ADS)

Kalejs, J. P.

1994-06-01

This report describes the impact of the technical achievements made in the first 18 months of the three year PVMaT program at Mobil Solar on lowering the manufacturing costs of its photovoltaic polycrystalline silicon-based modules. Manufacturing cost decreases are being achieved through a reduction of silicon material utilization, increases in productivity and yield in crystal growth, and through improvements in the laser cutting process for EFG wafers. The yield, productivity, and throughput advances made possible by these technical achievements are shown to be able to enhance future market share growth for Mobil Solar products as a consequence of significant reductions in a number of direct manufacturing cost elements in EFG wafer and module production.

Overcoming the Law of the Hidden in Cyberinfrastructures.

PubMed

Bucksch, Alexander; Das, Abhiram; Schneider, Hannah; Merchant, Nirav; Weitz, Joshua S

2017-02-01

Cyberinfrastructure projects (CIPs) are complex, integrated systems that require interaction and organization amongst user, developer, hardware, technical infrastructure, and funding resources. Nevertheless, CIP usability, functionality, and growth do not scale with the sum of these resources. Instead, growth and efficient usage of CIPs require access to 'hidden' resources. These include technical resources within CIPs as well as social and functional interactions among stakeholders. We identify approaches to overcome resource limitations following the conceptual basis of Liebig's Law of the Minimum. In so doing, we recommend practical steps towards efficient and scaleable resource use, taking the iPlant/CyVerse CIP as an example. Copyright © 2016 Elsevier Ltd. All rights reserved.

Dynamic Tumor Growth Patterns in a Novel Murine Model of Colorectal Cancer

PubMed Central

Olson, Terrah J. Paul; Hadac, Jamie N.; Sievers, Chelsie K.; Leystra, Alyssa A.; Deming, Dustin A.; Zahm, Christopher D.; Albrecht, Dawn M.; Nomura, Alice; Nettekoven, Laura A.; Plesh, Lauren K.; Clipson, Linda; Sullivan, Ruth; Newton, Michael A.; Schelman, William R.; Halberg, Richard B.

2014-01-01

Colorectal cancer (CRC) often arises from adenomatous colonic polyps. Polyps can grow and progress to cancer, but may also remain static in size, regress, or resolve. Predicting which progress and which remain benign is difficult. We developed a novel long-lived murine model of CRC with tumors that can be followed by colonoscopy. Our aim was to assess whether these tumors have similar growth patterns and histologic fates to human colorectal polyps to identify features to aid in risk-stratification of colonic tumors. Long-lived ApcMin/+ mice were treated with dextran sodium sulfate to promote colonic tumorigenesis. Tumor growth patterns were characterized by serial colonoscopy with biopsies obtained for immunohistochemistry and gene expression profiling. Tumors grew, remained static, regressed, or resolved over time with different relative frequencies. Newly developed tumors demonstrated higher rates of growth and resolution than more established tumors that tended to remain static in size. Colonic tumors were hyperplastic lesions (3%), adenomas (73%), intramucosal carcinomas (20%), or adenocarcinomas (3%). Interestingly, the level of β-catenin was higher in adenomas that became intratumoral carcinomas as compared to those that failed to progress. In addition, differentially expressed genes between adenomas and intramucosal carcinomas were identified. This novel murine model of intestinal tumorigenesis develops colonic tumors that can be monitored by serial colonoscopy, mirror growth patterns seen in human colorectal polyps, and progress to CRC. Further characterization of cellular and molecular features are needed to determine which features can be used to risk-stratify polyps for progression to CRC and potentially guide prevention strategies. PMID:24196829

Nutrition and Child Growth and Development in Tunisia. Interim Progress Report, (September 1, 1972--February 28, 1973).

ERIC Educational Resources Information Center

Young, Harben Boutourline

This interim report of the Yale Project describes the progress made on the nutrition and growth study of Tunisian children from September 1, 1972 through February 28, 1973. A major part of the report is devoted to the organizational and data collection problems of the longitudinal study, discussed under the following categories: biomedics,…

Monitoring Children with Reading Disabilities' Response to Phonics Intervention: Are There Differences between Intervention Aligned and General Skill Progress Monitoring Assessments?

ERIC Educational Resources Information Center

Olinghouse, Natalie G.; Lambert, Warren; Compton, Donald L.

2006-01-01

This study investigated whether 2 different progress monitoring assessments differentially predicted growth in reading skills associated with systematic phonics instruction. Oral reading fluency (ORE) was compared with an intervention aligned word list (IAWL) as predictors of growth in untimed and timed decoding and word identification and text…

Growth on Oral Reading Fluency Measures as a Function of Special Education and Measurement Sufficiency

ERIC Educational Resources Information Center

Tindal, Gerald; Nese, Joseph F. T.; Stevens, Joseph J.; Alonzo, Julie

2016-01-01

For 30 years, researchers have investigated oral reading fluency as a measure of growth in reading proficiency. Yet, little research has been done with these measures in the context of progress monitoring in Tier 2 systems. First, we document teachers' progress-monitoring decisions on type of passage (on-grade or off-grade) and how often to…

Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109

PubMed Central

Hockla, Alexandra; Radisky, Derek C.

2010-01-01

Serine proteases have been implicated in many stages of cancer development, facilitating tumor cell growth, invasion, and metastasis, and naturally occurring serine protease inhibitors have shown promise as potential anticancer therapeutics. Optimal design of inhibitors as potential therapeutics requires the identification of the specific serine proteases involved in disease progression and the functional targets responsible for the tumor-promoting properties. Here, we use the HMT-3522 breast cancer progression series grown in 3D organotypic culture conditions to find that serine protease inhibitors cause morphological reversion of the malignant T4-2 cells, assessed by inhibition of proliferation and formation of acinar structures with polarization of basal markers, implicating serine protease activity in their malignant growth behavior. We identify PRSS3/mesotrypsin upregulation in T4-2 cells as compared to their nonmalignant progenitors, and show that knockdown of PRSS3 attenuates, and treatment with recombinant purified mesotrypsin enhances, the malignant growth phenotype. Using proteomic methods, we identify CD109 as the functional proteolytic target of mesotrypsin. Our study identifies a new mediator and effector of breast cancer growth and progression. PMID:20035377

Technical Vocational Education and Training for Micro-Enterprise Development in Ethiopia: A Solution or Part of the Problem?

ERIC Educational Resources Information Center

Gondo, Tendayi; Dafuleya, Gift

2010-01-01

Technical vocational education and training (TVET) programmes have recently received increased attention as an area of priority for stimulating growth in developed and developing countries. This paper considers the situation in Ethiopia where the promotion of micro and small-sized enterprises (MSEs) has been central to the development and…

Technical Education in Pre and Post Independent India

ERIC Educational Resources Information Center

Janardhana, G.; Rajasekhar, M.

2012-01-01

This paper deals with technical education growth, policies in pre and post independent India. The world is moving forward rapidly and positively, into an era where societies and economies are incrementally based on knowledge. The importance of nations in the 21st Century shall be judged not by their economic strength alone, but also by their power…

Technical and Professional Communication Programs and the Small College Setting: Opportunities and Challenges

ERIC Educational Resources Information Center

Latterell, Catherine G.

2003-01-01

This article argues that the small school context has been a relatively unexamined or under-examined context for technical and professional communication program development. While graduate program development holds a large share of the field's attention in recent national forums, growth in graduate programs is a consequence of demand in the job…

Exploring the Misrepresentation of Nigerian Women in Technical and Vocational Education in Polytechnic Institution

ERIC Educational Resources Information Center

Akor, Robert; Bakar, Ab Rahim Bin; Hamzah, Azim B. Hj.; Rashid, Abdullah Bin Mat

2014-01-01

Nigerian government is making frantic efforts to drive her economy by laying emphasis on technical and vocational education to enable her compete favorably in the global market. Emphasis of government is in Polytechnic education where skills for self-reliant and economic growth are a priority. However, women are not embracing this opportunity by…

Managers' roles in the professional growth of Iranian clinical nurses.

PubMed

Rahimaghaee, Flora; Nayeri, Nahid Dehghan; Mohammadi, Eesa

2010-12-01

Any progressive organization should consider investing in its clinical nurses' professional growth if it desires to survive and succeed in offering care. Managers play a significant role in facilitating clinical nurses' professional growth. A content analysis study was conducted with 20 clinical nurses and managers in Iran in order to describe how they experienced managers' roles in relation to their professional growth. They believed that managers played two major roles in their professional growth process: motivating and inhibiting. From the participants' point of view, managers, through supporting, encouraging, and valuing staff and creating opportunities for learning, played a facilitating role in their professional growth. But, whenever the staff did not receive this support, they became discouraged and did not make any progress. The results can be used to improve management and, consequently, to enhance the professional growth of staff. © 2010 Blackwell Publishing Asia Pty Ltd.

YAP forms autocrine loops with the ERBB pathway to regulate ovarian cancer initiation and progression

PubMed Central

He, Chunbo; Lv, Xiangmin; Hua, Guohua; Lele, Subodh M; Remmenga, Steven; Dong, Jixin; Davis, John S; Wang, Cheng

2014-01-01

Mechanisms underlying ovarian cancer initiation and progression are unclear. Herein, we report that the Yes-associated protein (YAP), a major effector of the Hippo tumor suppressor pathway, interacts with ERBB signaling pathways to regulate the initiation and progression of ovarian cancer. Immunohistochemistry studies indicate that YAP expression is associated with poor clinical outcomes in patients. Overexpression or constitutive activation of YAP leads to transformation and tumorigenesis in human ovarian surface epithelial cells, and promotes growth of cancer cells in vivo and in vitro. YAP induces expression of EGF receptors (EGFR, ERBB3) and production of EGF-like ligands (HBEGF, NRG1 and NRG2). HBEGF or NRG1, in turn, activates YAP and stimulates cancer cell growth. Knockdown of ERBB3 or HBEGF eliminates YAP effects on cell growth and transformation, while knockdown of YAP abrogates NRG1- and HBEGF-stimulated cell proliferation. Collectively, our study demonstrates the existence of HBEGF&NRGs/ERBBs/YAP/HBEGF&NRGs autocrine loop that controls ovarian cell tumorigenesis and cancer progression. PMID:25798835

Concepts in solid tumor evolution.

PubMed

Sidow, Arend; Spies, Noah

2015-04-01

Evolutionary mechanisms in cancer progression give tumors their individuality. Cancer evolution is different from organismal evolution, however, and we discuss where concepts from evolutionary genetics are useful or limited in facilitating an understanding of cancer. Based on these concepts we construct and apply the simplest plausible model of tumor growth and progression. Simulations using this simple model illustrate the importance of stochastic events early in tumorigenesis, highlight the dominance of exponential growth over linear growth and differentiation, and explain the clonal substructure of tumors. Copyright © 2015 Elsevier Ltd. All rights reserved.

The contribution of growth hormone to mammary neoplasia

PubMed Central

Perry, Jo K; Mohankumar, Kumarasamypet M; Emerald, B Starling; Mertani, Hichem C; Lobie, Peter E

2008-01-01

While the effects of growth hormone (GH) on longitudinal growth are well established, the observation that GH contributes to neoplastic progression is more recent. Accumulating literature implicates GH-mediated signal transduction in the development and progression of a wide range malignancies including breast cancer. Recently autocrine human GH been demonstrated to be an orthotopically expressed oncogene for the human mammary gland. This review will highlight recent evidence linking GH and mammary carcinoma and discuss GH-antagonism as a potential therapeutic approach for treatment of breast cancer. PMID:18253708

Information Handling in Selected Academic Libraries of the Caribbean.

ERIC Educational Resources Information Center

Rodriguez, Ketty

1988-01-01

Describes a survey that examined the extent of library technical processes automation within academic libraries at 10 Caribbean universities. Existing conditions, steps in progress, and plans for future automation are discussed. (8 references) (CLB)

48 CFR 2052.211-71 - Technical progress report.

Code of Federal Regulations, 2010 CFR

2010-10-01

... investigator, the contract period of performance, and the period covered by the report. Each report must include the following for each discrete task/task order: (a) A listing of the efforts completed during the...

10 CFR 603.885 - Updated program plans and budgets.

Code of Federal Regulations, 2011 CFR

2011-01-01

... program plans and budgets. In addition to reports on progress to date, a TIA may include a provision requiring the recipient to annually prepare an updated technical plan for future conduct of the research...

Technical Progress: Three Ways to Keep Up.

ERIC Educational Resources Information Center

Patterson, J. Wayne; And Others

1988-01-01

The authors analyzed three techniques employed in technological forecasting: (1) brainstorming, (2) extrapolation, and (3) scenario writing. They argue that these techniques have value to practitioners, particularly managers, who are often affected by technological change. (CH)

QUARTERLY TECHNICAL PROGRESS REPORT, JULY, AUGUST, SEPTEMBER 1967.

DTIC Science & Technology

Contents: Circuit research program; Hardware systems research; Computer system software research; Illinois pattern recognition computer: ILLIAC II... service , use, and program development; IBM 7094/1401 service , use, and program development; Problem specifications; General laboratory information.

Physics Division annual progress report for period ending December 31, 1975. [ORNL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1976-05-01

Separate abstracts were prepared for each of the data-containing sections of this report. Additional sections deal with publications, titles of papers presented at scientific and technical meetings, personnel, etc. (RWR)

Patterns of long bone growth in a mid-19th century documented sample of the urban poor from Bethnal Green, London, UK.

PubMed

Ives, Rachel; Humphrey, Louise

2017-05-01

Studies of male and female long bone growth in past populations are limited and usually constrained by the lack of personal identification. This article aimed to evaluate long bone growth in a series of mid-19 th century documented burials associated with the urban poor from Bethnal Green, London, UK. Maximum diaphyseal lengths from 74 males and 70 females (2 months to 12 years) were compared to modern reference data from North America. Diaphyseal lengths were expressed as a percentage of expected length and an average percentage value was calculated across all available long bones. An index of growth progression was introduced to explore differences in the progress of males and females towards their projected adult size. Deviation from the expected growth attainment was evident in both sexes in the archaeological series by 2-4 months of age. Only 19.4% (28/144) of the children had attained an average long bone length >90% of the predicted mean in the reference series. The percentage of expected growth attainment decreased steadily in both sexes during infancy and early childhood. Overall, females deviated further from their expected growth progression than males. Growth faltering in both males and females was established during infancy (<1 year) with no evidence for recovery in older age groups. Early weaning and inadequate artificial feeding, together with impoverished living conditions and limited sanitary provision, most likely impacted on childhood growth. © 2017 Wiley Periodicals, Inc.

NASA/DOE automotive Stirling engine project: Overview 1986

NASA Technical Reports Server (NTRS)

Beremand, D. G.; Shaltens, R. K.

1986-01-01

The DOE/NASA Automotive Stirling Engine Project is reviewed and its technical progress and status are presented. Key technologies in materials, seals, and piston rings are progressing well. Seven first-generation engines, and modifications thereto, have accumulated over 15,000 hr of test time, including 1100hr of in-vehicle testing. Results indicate good progress toward the program goals. The first second-generation engine is now undergoing initial testing. It is expected that the program goal of a 30-percent improvement in fuel economy will be achieved in tests of a second-generation engine in a Celebrity vehicle.

DOE/NASA automotive Stirling engine project - Overview 86

NASA Technical Reports Server (NTRS)

Beremand, D. G.; Shaltens, R. K.

1986-01-01

The DOE/NASA Automotive Stirling Engine Project is reviewed and its technical progress and status are presented. Key technologies in materials, seals, and piston rings are progressing well. Seven first-generation engines, and modifications thereto, have accumulated over 15,000 hr of test time, including 1100 hr of in-vehicle testing. Results indicate good progress toward the program goals. The first second-generation engine is now undergoing initial testing. It is expected that the program goal of a 30-percent improvement in fuel economy will be achieved in tests of a second-generation engine in a Celebrity vehicle.

The Relationship between Career Growth and Organizational Commitment

ERIC Educational Resources Information Center

Weng, Qingxiong; McElroy, James C.; Morrow, Paula C.; Liu, Rongzhi

2010-01-01

This research examines the relationship between employees' career growth and organizational commitment. Career growth was conceptualized by four factors: career goal progress, professional ability development, promotion speed and remuneration growth, while organizational commitment was conceptualized using Meyer and Allen's (1997) three component…

ENVIROMENTALLY BENIGN MITIGATION OF MICROBIOLOGICALLY INFLUENCED CORROSION (MIC)

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. Robert Paterek; Gemma Husmillo; Amrutha Daram

The overall program objective is to develop and evaluate environmentally benign agents or products that are effective in the prevention, inhibition, and mitigation of microbially influenced corrosion (MIC) in the internal surfaces of metallic natural gas pipelines. The goal is to develop one or more environmentally benign (a.k.a. ''green'') products that can be applied to maintain the structure and dependability of the natural gas infrastructure. The technical approach for this quarter includes the application of the method of fractionation of the extracts by high performance liquid chromatography (HPLC); determination of antimicrobial activities of the new extracts and fractions using amore » growth inhibition assay, and evaluation of the extracts' ability to inhibit biofilm formation. We initiated the delivery system for these new biocides in the test cell and in mixtures of foam components and biocides/anti-biofilms. A total of 51 fractions collected by HPLC from crude extracts that were obtained from three varieties of Capsicum sp. (Serrano, Habanero, Chile de Arbol) were subjected to growth inhibition tests against two SRB strains, D. vulgaris and D. desulfuricans. Five fractions showed growth inhibition against both strains while seven inhibited D. desulfuricans only. The crude extracts did not show growth inhibition on both strains but were proven to be potent in preventing the formation of biofilm. Growth inhibition tests of the same set of crude extracts against Comamonas denitrificans did not show positive results. The fractions will be subjected to biofilm inhibition and dissociation assay as well. The delivery system to be evaluated first was foam. The ''foam pig'' components of surfactants and water were tested with the biocide addition. The first chemical and physical parameters to be tested were pH and surfactants. Tests using the fractionated pepper extracts are progressing rapidly. Gas chromatographic analysis on a number of fractions is underway. Involvement of other microorganisms in the tests will be extended. The foam application method has been initiated and is being developed.« less

FY2013 Energy Storage R&D Progress Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

none,

2014-02-01

The FY 2013 Progress Report for Energy Storage R&D focuses on advancing the development of batteries to enable a large market penetration of hybrid and electric vehicles. Program targets focus on overcoming technical barriers to enable market success including: (1) significantly reducing battery cost, (2) increasing battery performance (power, energy, durability), (3) reducing battery weight & volume, and (4) increasing battery tolerance to abusive conditions such as short circuit, overcharge, and crush.

Vocational Education--A Decade of Progress. 10th Annual Report of the Advisory Council for Technical-Vocational Education in Texas to the State Board for Vocational Education.

ERIC Educational Resources Information Center

Texas Advisory Council for Technical - Vocational Education, Austin.

Assessment of the present status of vocational education in Texas and recommended priorities for the future constitute this annual report. Part 1 documents the progress of the 1970s and lists 15 challenges for vocational education in the 1980s, including application of meaningful evaluation procedures and careful program planning to maximize cost…

Slow Progress In Finalizing Measles And Rubella Elimination In The European Region.

PubMed

Biellik, Robin; Davidkin, Iria; Esposito, Susanna; Lobanov, Andrey; Kojouharova, Mira; Pfaff, Günter; Santos, José Ignacio; Simpson, John; Mamou, Myriam Ben; Butler, Robb; Deshevoi, Sergei; Huseynov, Shahin; Jankovic, Dragan; Shefer, Abigail

2016-02-01

All countries in the World Health Organization European Region committed to eliminating endemic transmission of measles and rubella by 2015, and disease incidence has decreased dramatically. However, there was little progress between 2012 and 2013, and the goal will likely not be achieved on time. Genuine political commitment, increased technical capacity, and greater public awareness are urgently needed, especially in Western Europe. Project HOPE—The People-to-People Health Foundation, Inc.

Sonar Test and Test Instrumentation Support.

DTIC Science & Technology

1979-03-29

AD-AlSO 055 TEXAS UNIV AT AUSTIN APPLIED RESEARCH LABS F/6 17/1 SONAR TEST AND TEST INSTRUMENTATION SUPPORT (U) MAR 79 0 D BAKER N00140-76-C-64a7... SONAR TEST AND TEST INSTRUMENTATION SUPPORT quarterly progress report September - 30 November 197Pj 6. PERFORMING ORG. REPORT NUMBER 7. AUTHOR(e) S...involves technical support with sonar testing, test instrumentation, and documentation. This report describes progress made under the tasks that are

Parameter identification for nonlinear aerodynamic systems

NASA Technical Reports Server (NTRS)

Pearson, Allan E.

1993-01-01

This final technical report covers a three and one-half year period preceding February 28, 1993 during which support was provided under NASA Grant NAG-1-1065. Following a general description of the system identification problem and a brief survey of methods to attack it, the basic ideas behind the approach taken in this research effort are presented. The results obtained are described with reference to the published work, including the five semiannual progress reports previously submitted and two interim technical reports.

LINER FOR EXTRUSION BILLET CONTAINERS. Interim Technical Documentary Progress Report, June 5, 1962-September 5, 1962

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spachner, S.A.

1962-10-31

A container-sleeve-liner assembly was designed which will provide adequate support for ceramic, ceramic coated metal, or metal liners. The design minimizes mechanical property requirements of liner materials, and permits rapid removal of worn or damaged liners. A high-strength stem was designed and fabricated. Technical literature on high-strength materials was reviewed, and high-strength materials producers were contacted to locate sources and assess applicability of existing materials for refractory metal extrusion liner use. (auth)

Experimental Program Final Technical Progress Report: 15 February 2007 to 30 September 2012

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kinney, Edward R.

2014-09-12

This is the final technical report of the grant DE-FG02-04ER41301 to the University of Colorado at Boulder entitled "Intermediate Energy Nuclear Physics" and describes the results of our funded activities during the period 15 February 2007 to 30 September 2012. These activities were primarily carried out at Fermilab, RHIC, and the German lab DESY. Significant advances in these experiments were carried out by members of the Colorado group and are described in detail.

The patient-sensor interface

PubMed Central

Crockett, G. S.

1970-01-01

During the assessment of monitoring equipment on acute medical cases in a general ward, a quantitative investigation of technical faults revealed that 44% of these occurred at the patient-sensor interface. While the attachment of the equipment was accepted by the patient and was suitable for application by nursing staff, this degree of technical breakdown indicates that more progress is necessary in the design of this aspect of monitoring equipment before it is possible to have a reliable system. ImagesFig. 1 PMID:5476136

Addressing tomorrow's DMO technical challenges today

NASA Astrophysics Data System (ADS)

Milligan, James R.

2009-05-01

Distributed Mission Operations (DMO) is essentially a type of networked training that pulls in participants from all the armed services and, increasingly, allies to permit them to "game" and rehearse highly complex campaigns, using a mix of local, distant, and virtual players. The United States Air Force Research Laboratory (AFRL) is pursuing Science and Technology (S&T) solutions to address technical challenges associated with distributed communications and information management as DMO continues to progressively scale up the number, diversity, and geographic dispersal of participants in training and rehearsal exercises.

AGOR 28: SIO Shipyard Representative Bi-Weekly Progress Report

DTIC Science & Technology

2014-03-13

652/0 AGOR27 A055 TM Report - COMMERCIAL TECHNICAL MANUALS AND SUPPLEMENTAL DATA ( #368 DI-055 (TM) for 555c Kidde Fire Systems Fuel Shunt System ...TM) for 521 Fire Main System High-Level Manual) (R/ASR) 763/0 AGOR27 A055 TM Report - COMMERCIAL TECHNICAL MANUALS AND SUPPLEMENTAL DATA ( #384...Report - SINGLE SYSTEM VENDOR (SSV) DESIGN REVIEW AGENDAS AND MINUTES ( SSV #7 MINUTES AND SIGN-IN SHEET) (R/ASR) 47/0 AGOR27 A027- 41 DWG Report

LUVOIR Tech Notes

NASA Technical Reports Server (NTRS)

Bolcar, Matthew R.; Shaklan, Stuart; Roberge, Aki; Rioux, Norman; Feinberg, Lee; Werner, Michael; Rauscher, Bernard; Mandell, Avi; France, Kevin; Schiminovich, David

2016-01-01

We present nine "tech notes" prepared by the Large UV/Optical/Infrared (LUVOIR) Science and Technology Definition Team (STDT), Study Office, and Technology Working Group. These tech notes are intended to highlight technical challenges that represent boundaries in the trade space for developing the LUVOIR architecture that may impact the science objectives being developed by the STDT. These tech notes are intended to be high-level discussions of the technical challenges and will serve as starting points for more in-depth analysis as the LUVOIR study progresses.

Research and Technology Objectives and Plans Summary (RTOPS)

NASA Technical Reports Server (NTRS)

1990-01-01

The NASA research and technology program for FY 1990 is presented. The summary portions is compiled of each of the RTOPs (Research and Technology Objectives and Plans) used for management review and control of research currently in progress throughout NASA. The RTOP summary is designed to facilitate communication and coordination among concerned technical personnel in government, industry, and universities. The first section containing citations and abstracts of the RTOPs is followed by four indices: Subject; Technical Monitor; Responsible NASA Organization; and RTOP number.

mTORC1 activation blocks BrafV600E-induced growth-arrest, but is insufficient for melanoma formation

PubMed Central

Damsky, William; Micevic, Goran; Meeth, Katrina; Muthusamy, Viswanathan; Curley, David P.; Santhankrishnan, Manjula; Erdelyi, Ildiko; Platt, James T.; Huang, Laura; Theodosakis, Nicholas; Zaidi, M. Raza; Tighe, Scott; Davies, Michael A.; Dankort, David; McMahon, Martin; Merlino, Glenn; Bardeesy, Nabeel; Bosenberg, Marcus

2014-01-01

SUMMARY BrafV600E induces benign, growth-arrested melanocytic nevus development, but also drives melanoma formation. Cdkn2a loss in BrafV600E melanocytes in mice results in rare progression to melanoma, but only after stable growth arrest as nevi. Immediate progression to melanoma is prevented by upregulation of miR-99/100 which downregulates mTOR and IGF1R signaling. mTORC1 activation through Stk11 (Lkb1) loss abrogates growth-arrest of BrafV600E melanocytic nevi, but is insufficient for complete progression to melanoma. Cdkn2a loss is associated with mTORC2 and Akt activation in human and murine melanocytic neoplasms. Simultaneous Cdkn2a and Lkb1 inactivation in BrafV600E melanocytes results in activation of both mTORC1 and mTORC2/Akt, inducing rapid melanoma formation in mice. In this model, activation of both mTORC1/2 is required for Braf-induced melanomagenesis. PMID:25584893

Biomarkers of Renal Tumor Burden and Progression in TSC

DTIC Science & Technology

2012-09-01

code) Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std. Z39.18 Biomarkers of Renal Tumor Burden and Progression in TSC Dr. Elahna Paul 1...appearance and growth rates) and renal function parameters (e.g. blood pressure, serum chemistries, urinalysis and urine chemistries). (2) Measure...and renal function parameters (e.g. blood pressure, serum chemistries, urinalysis and urine chemistries). (2) Measure soluble growth factors

Modeling the environmental growth of Pseudogymnoascus destructans and its impact on the white-nose syndrome epidemic.

PubMed

Reynolds, Hannah T; Ingersoll, Tom; Barton, Hazel A

2015-04-01

White-nose syndrome (WNS) has had a devastating effect on North American bat populations. The causal agent of WNS is the fungal pathogen, Pseudogymnoascus destructans (Pd), which has been shown to persist in caves after the eradication of host populations. As nonpathogenic Pseudogymnoascus spp. display saprophytic growth and are among the most commonly isolated fungi from caves, we examined whether Pd could grow in cave sediments and the contribution such growth could have to WNS disease progression. We inoculated a range of diverse cave sediments and demonstrated the growth of Pd in all sediments tested. These data indicate that environmental growth of Pd could lead to the accumulation of spores above the estimated infection threshold for WNS, allowing environment-to-bat infection. The obtained growth parameters were then used in a susceptible-infected-susceptible mathematic model to determine the possible contribution of environmental Pd growth to WNS disease progression in a colony of little brown bats (Myotis lucifugus). This model suggests that the environmental growth of Pd would increase WNS infection rates, particularly in colonies experiencing longer hibernation periods or in hibernacula with high levels of organic detritus. The model also suggests that once introduced, environmental Pd growth would allow the persistence of this pathogen within infected hibernacula for decades, greatly compromising the success of bat reintroduction strategies. Together these data suggest that Pd is not reliant on its host for survival and is capable of environmental growth and amplification that could contribute to the rapid progression and long-term persistence of WNS in the hibernacula of threatened North American bats.

Proceedings of the Second Noncontact Temperature Measurement Workshop

NASA Technical Reports Server (NTRS)

Hale, Robert R. (Editor)

1989-01-01

The state of the art in noncontact temperature measurement (NCTM) technology was reviewed and the NCTM requirements of microgravity materials processing community identified. The workshop included technical presentations and discussions which ranged from research on advanced concepts for temperature measurement to laboratory research and development regarding measurement principles and state-of-the-art engineering practices for NCTM methodology in commercial and industrial applications. Technical presentations were made concerning: NCTM needs as perceived by several NASA centers, recent ground-based NCT, research and development of industry, NASA, academia, and selected national laboratories, work-in-progress communication, and technical issues of the implementation of temperature measurement in the space environment to facilitate future U.S. materials science investigations.

A systems approach to implementation of eLearning in medical education: five MEPI schools' journeys.

PubMed

Vovides, Yianna; Chale, Selamawit Bedada; Gadhula, Rumbidzayi; Kebaetse, Masego B; Nigussie, Netsanet Animut; Suleman, Fatima; Tibyampansha, Dativa; Ibrahim, Glory Ramadhan; Ntabaye, Moshi; Frehywot, Seble; Nkomazana, Oathokwa

2014-08-01

How should eLearning be implemented in resource-constrained settings? The introduction of eLearning at four African medical schools and one school of pharmacy, all part of the Medical Education Partnership Initiative (MEPI) eLearning Technical Working Group, highlighted the need for five factors essential for successful and sustainable implementation: institutional support; faculty engagement; student engagement; technical expertise; and infrastructure and support systems. All five MEPI schools reported strengthening technical expertise, infrastructure, and support systems; four schools indicated that they were also successful in developing student engagement; and three reported making good progress in building institutional support. Faculty engagement was the one core component that all five schools needed to enhance.

The Center for Space Telemetering and Telecommunications Systems

NASA Technical Reports Server (NTRS)

Horan, S.; DeLeon, P.; Borah, D.; Lyman, R.

2003-01-01

This report comprises the final technical report for the research grant 'Center for Space Telemetering and Telecommunications Systems' sponsored by the National Aeronautics and Space Administration's Goddard Space Flight Center. The grant activities are broken down into the following technology areas: (1) Space Protocol Testing; (2) Autonomous Reconfiguration of Ground Station Receivers; (3) Satellite Cluster Communications; and (4) Bandwidth Efficient Modulation. The grant activity produced a number of technical reports and papers that were communicated to NASA as they were generated. This final report contains the final summary papers or final technical report conclusions for each of the project areas. Additionally, the grant supported students who made progress towards their degrees while working on the research.

The Effect of Hyperbaric Oxygen on the Growth of Rhizopus nigricans.

DTIC Science & Technology

1980-12-01

identify by block number) Impression Chamber Medical Mycology Oxygen Therapy (ompression Therapy Mucor Phycomycosis hvp)erbaric Medicine Mucormycosis...rado. 3. Cai rnev, W. J. 1980. The effect of hyperbaric oxygen on the growth of Mucor sp. and Aspergillus fumigLatus. Technical Report FJSRL-TR- 80

Growth of Engineering Education in India: Status, Issues, and Challenges

ERIC Educational Resources Information Center

Choudhury, Pradeep Kumar

2016-01-01

This article examines the growth of engineering education in India in the post-economic reform period using the secondary data published by Ministry of Human Resource Development, University Grants Commission and All India Council for Technical Education. Particularly, this article has focused on three important dimensions of engineering and…

Education, Human Capital Enhancement and Economic Development--Comparison between Korea and Taiwan.

ERIC Educational Resources Information Center

Lee, Maw-Lin; And Others

1994-01-01

Examines major determinants of economic development in South Korea and Taiwan. Investigates the role of human capital, measured by educational attainment, in driving output growth and enlarging the labor income share. Physical capital accumulation and export expansion affected output growth in both nations. Although technical progress…