A comparison of petrophysical data inputs for establishing time-depth relationships: a guide for future drilling expeditions

NASA Astrophysics Data System (ADS)

Boaga, J.; Sauermilch, I.; Mateo, Z. R. P.

2017-12-01

Time-depth relationships (TDR) are crucial in correlating drillhole and core information to seismic reflection profiles, for accurate resource estimation, scientific interpretation and to guide drilling operations. Conventional seismic time-depth domain conversion utilizes downhole sonic logs (DSI), calibrated using available checkshot data, which are local travel times from the surface to a particular depth. Scientific drilling programs (ODP and IODP) also measure P-wave velocity (PWL or C) on recovered core samples. Only three percent of all ODP and IODP sites record all three velocity measurements, however this information can be instructive as sometimes these data input show dissimilar TDR. These representative sites provide us with an opportunity to perform a comparative analysis highlighting the differences and similarities of TDRs derived from checkshot, downhole, and laboratory measurements. We then discuss the impact of lithology, stratigraphy, water column and other petrophysical properties in the predictive accuracy of TDR calculations, in an effort to provide guidance for future drilling and coring expeditions.

Consumer Education: Ecological Resource Management. Home & Family Life Curriculum Guide: H.E. Bulletin No. 43.

ERIC Educational Resources Information Center

Washington Office of the State Superintendent of Public Instruction, Olympia.

The future ability of secondary students to interact in a progressively technologically-oriented society is the purpose of this curriculum guide on consumer education. The guide teaches consumer decision-making, resource management, and advocacy/action. The introduction discusses the future of society and technology. Each of three sections…

Examining the moderating role of family cohesion on the relationship between witnessed community violence and delinquency in a national sample of adolescents.

PubMed

Barr, Simone C; Hanson, Rochelle; Begle, Angela M; Kilpatrick, Dean G; Saunders, Benjamin; Resnick, Heidi; Amstadter, Ananda

2012-01-01

Witnessed community violence has been linked to a number of internalizing and externalizing problems in adolescents. Guided by Cicchetti and Lynch's (1993) ecological-transactional model, this study aimed to examine the impact that family-level factors had on negative outcomes associated with witnessed community violence. Using a nationally representative sample, we explored the moderational role of family cohesion in the relationship between witnessing community violence and delinquent behavior while taking demographic variables into account. Results from the investigation suggested that low levels of family cohesion were predictive of delinquency after controlling for race, gender, past delinquency, and direct trauma. In addition, the findings suggested that family cohesion moderated the impact of witnessed community violence on future delinquent behavior. Future directions for research and implications for practice were also discussed.

Endobronchial ultrasound-guided transbronchial needle aspiration for staging of lung cancer: a concise review.

PubMed

Aziz, Fahad

2012-09-01

Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) offers a minimally invasive alternative to mediastinoscopy with additional access to the hilar nodes, a better safety profile, and it removes the costs and hazards of theatre time and general anesthesia with comparable sensitivity, although the negative predictive value of mediastinoscopy (and sample size) is greater. EBUS- TBNA also obtains larger samples than conventional TBNA, has superior performance and theoretically is safer, allowing real-time sampling under direct vision. It can also have predictive value both in sonographic appearance of the nodes and histological characteristics. EBUS-TBNA is therefore indicated for NSCLC staging, diagnosis of lung cancer when there is no endobronchial lesion, and diagnosis of both benign (especially tuberculosis and sarcoidosis) and malignant mediastinal lesions. The procedure is different than for flexible bronchoscopy, takes longer, and requires more training. EBUS-TBNA is more expensive than conventional TBNA but can save costs by reducing the number of more costly mediastinoscopies. In the future, endobronchial ultrasound may have applications in airways disease and pulmonary vascular disease.

Scientific American Frontiers Teaching Guides for Shows 701-705, October 1996-April 1997.

ERIC Educational Resources Information Center

Connecticut Public Television, Hartford.

These teaching guides are meant to supplement the seventh season (1996-97) of the PBS Series "Scientific American Frontiers". Episode 701 is entitled "Inventing the Future: A Tour of the MIT Media Lab" and the teaching guide contains information and activities on a virtual pet dog, computers of the future, a smart car designed…

A Miniature Laser Desorption/Ionization Time-of-Flight Mass Spectrometer for in Situ Analysis of Mars Surface Composition and Identification of Hazard in Advance of Future Manned Exploration

NASA Technical Reports Server (NTRS)

Getty, S. A.; Brinckerhoff, W. B.; Arevalo, R. D.; Floyd, M. M.; Li, X.; Cornish, T.; Ecelberger, S. A.

2012-01-01

Future landed missions to Mars will be guided by two strategic directions: (1) sample return to Earth, for comprehensive compositional analyses, as recommended by the 2011 NRC Planetary Decadal Survey; and (2) preparation for human exploration in the 2030s and beyond, as laid out by US space policy. The resultant mission architecture will likely require high-fidelity in situ chemical/organic sample analyses within an extremely constrained resource envelope. Both science goals (e.g., MEPAG Goal 1, return sample selection, etc.) as well as identification of any potential toxic and biological hazards to humans, must be addressed. Over the past several years of instrument development, we have found that the adaptable, compact, and highly capable technique of laser desorption/ionization time-of-flight mass spectrometry (LD-TOF-MS) has significant potential to contribute substantially to these dual objectives. This concept thus addresses Challenge Area 1: instrumentation and Investigation Approaches.

Ice detection and classification on an aircraft wing with ultrasonic shear horizontal guided waves.

PubMed

Gao, Huidong; Rose, Joseph L

2009-02-01

Ice accumulation on airfoils has been identified as a primary cause of many accidents in commercial and military aircraft. To improve aviation safety as well as reduce cost and environmental threats related to aircraft icing, sensitive, reliable, and aerodynamically compatible ice detection techniques are in great demand. Ultrasonic guided-wave-based techniques have been proved reliable for "go" and "no go" types of ice detection in some systems including the HALO system, in which the second author of this paper is a primary contributor. In this paper, we propose a new model that takes the ice layer into guided-wave modeling. Using this model, the thickness and type of ice formation can be determined from guided-wave signals. Five experimental schemes are also proposed in this paper based on some unique features identified from the guided- wave dispersion curves. A sample experiment is also presented in this paper, where a 1 mm thick glaze ice on a 2 mm aluminum plate is clearly detected. Quantitative match of the experiment data to theoretical prediction serves as a strong support for future implementation of other testing schemes proposed in this paper.

Guiding People to Interpret Their Experienced Difficulty as Importance Highlights Their Academic Possibilities and Improves Their Academic Performance

PubMed Central

Oyserman, Daphna; Elmore, Kristen; Novin, Sheida; Fisher, Oliver; Smith, George C.

2018-01-01

Does experiencing difficulty bolster or undermine future self-images, strategies to get there and actual performance? We build on four insights from prior research to predict that accessible interpretation-of-experienced-difficulty mindset shapes identity and performance. First, people have two different interpretation-of-experienced-difficulty mindsets available in memory; their difficulty-as-impossibility mindset focuses attention on difficulty as implying low odds and their difficulty-as-importance mindset focuses attention on difficulty as implying high value. Second, people are sensitive to contextual cues as to which mindset to apply to understand their experienced difficulty. Third, people apply the mindset that comes to mind unless they have reason to question why it is “on-the-mind.” Fourth, social class can be thought of as a chronic context influencing how much people endorse each interpretation-of-experienced-difficulty mindset. We used subtle primes to guide participants’ attention toward either a difficulty-as-importance or a difficulty-as-impossibility mindset (N = 591). Participants guided toward a difficulty-as-importance mindset performed better on difficult academic tasks (Studies 1, 2) than participants guided toward a difficulty-as-impossibility mindset; whether they had more school-focused possible identities and linked strategies depended on sample (Studies 3, 4). For college students, the effect of guided interpretation-of-experienced-difficulty mindset was not moderated by how much participants agreed with that mindset (Studies 1, 3, 4). College students mostly disagreed with a difficulty-as-impossibility mindset, but making that mindset accessible undermined their performance and sometimes their possible identities anyway. In contrast, middle school students (a younger and lower social class sample) were more likely to agree with a difficulty-as-impossibility mindset. In this sample (Study 2), we found an effect of mindset endorsement: agreeing that difficulty implies importance and disagreeing that difficulty implies impossibility improved performance. This study had a control group. Control group participants not guided to use a particular interpretation-of-experienced-difficulty mindset performed no differently than participants guided toward a difficulty-as-impossibility mindset. Results suggest that people may chronically act as if they are using a difficulty-as-impossibility mindset and may benefit from being guided to consider that experienced difficulty might imply task importance. Effect of accessible mindset on salience of academic possible selves was not stable, accessible mindset mattered in one university sample but not the other. PMID:29887819

The Annie E. Casey Foundation's New Futures Initiative: Strategic Planning Guide. (Revised).

ERIC Educational Resources Information Center

Center for the Study of Social Policy, Washington, DC.

Information in this guide is based on published research concerning effective strategies in dealing with at-risk youth. It was written for those communities invited to develop proposals under the Annie E. Casey Foundation's New Futures Initiative in an attempt to alleviate problems that compromise American children's futures. Each of three…

Programming Equity into Computer Education: Today's Guide to the Schools of the Future. A PEER Computer Equity Action Kit.

ERIC Educational Resources Information Center

Martin-McCormick, Lynda; And Others

An advocacy packet on educational equity in computer education consists of five separate materials. A booklet entitled "Today's Guide to the Schools of the Future" contains four sections. The first section, a computer equity assessment guide, includes interview questions about school policies and allocation of resources, student and teacher…

Examining the Moderating Role of Family Cohesion on the Relationship Between Witnessed Community Violence and Delinquency in a National Sample of Adolescents

PubMed Central

Barr, Simone C.; Hanson, Rochelle; Begle, Angela M.; Kilpatrick, Dean G.; Saunders, Benjamin; Resnick, Heidi; Amstadter, Ananda

2014-01-01

Witnessed community violence has been linked to a number of internalizing and externalizing problems in adolescents. Guided by Cicchetti and Lynch’s (1993) ecological-transactional model, this study aimed to examine the impact that family-level factors had on negative outcomes associated with witnessed community violence. Using a nationally representative sample, we explored the moderational role of family cohesion in the relationship between witnessing community violence and delinquent behavior while taking demographic variables into account. Results from the investigation suggested that low levels of family cohesion were predictive of delinquency after controlling for race, gender, past delinquency, and direct trauma. In addition, the findings suggested that family cohesion moderated the impact of witnessed community violence on future delinquent behavior. Future directions for research and implications for practice were also discussed. PMID:21920873

Dinosaurs and Power Plants. Energy from the Past for the Future. Teacher's Lesson Plan and Activity Guide; Teacher's Guide Supplement of Reproducible Graphics.

ERIC Educational Resources Information Center

Department of Energy, Washington, DC. Office of Fossil Energy.

This teacher's guide and its accompanying supplement were prepared for use with the U.S. Department of Energy's Dinosaurs and Power Plants, a publication designed for students in grades 5-8 about the history, detection, extraction, transportation, use, environmental problem/solutions, and future of fossil energy. The study of energy science shows…

Forward Contamination of the Moon and Mars: Implications for Future Life Detection Missions

NASA Technical Reports Server (NTRS)

Glavin, Daniel P.; Dworkin, Jason P.; Lupisella, Mark; Kminek, Gerhard; Rummel, John D.

2004-01-01

NASA and ESA have outlined new visions for solar system exploration that will include a series of lunar robotic missions to prepare for, and support a human return to the Moon, and future human exploration of Mars and other destinations. One of the guiding principles for exploration is to pursue compelling scientific questions about the origin and evolution of life. The search for life on objects such as Mars will require that all spacecraft and instrumentation be sufficiently cleaned and sterilized prior to launch to ensure that the scientific integrity of extraterrestrial samples is not jeopardized by terrestrial organic contamination. Under COSPAR's current planetary protection policy for the Moon, no sterilization procedures are required for outbound lunar spacecraft. Nonetheless, future in situ investigations of a variety of locations on the Moon by highly sensitive instruments designed to search for biologically derived organic compounds would help assess the contamination of the Moon by lunar spacecraft. These studies could also provide valuable "ground truth" data for Mars sample return missions and help define planetary protection requirements for future Mars bound spacecraft carrying life detection experiments. In addition, studies of the impact of terrestrial contamination of the lunar surface by the Apollo astronauts could provide valuable data to help refine future Mars surface exploration plans for a human mission to Mars.

Train the Trainer. Facilitator Guide Sample. Basic Blueprint Reading (Chapter One).

ERIC Educational Resources Information Center

Saint Louis Community Coll., MO.

This publication consists of three sections: facilitator's guide--train the trainer, facilitator's guide sample--Basic Blueprint Reading (Chapter 1), and participant's guide sample--basic blueprint reading (chapter 1). Section I addresses why the trainer should learn new classroom techniques; lecturing versus facilitating; learning styles…

Pre-Mission Input Requirements to Enable Successful Sample Collection by A Remote Field/EVA Team

NASA Technical Reports Server (NTRS)

Cohen, B. A.; Lim, D. S. S.; Young, K. E.; Brunner, A.; Elphic, R. E.; Horne, A.; Kerrigan, M. C.; Osinski, G. R.; Skok, J. R.; Squyres, S. W.;

The National Electronic Library: A Guide to the Future for Library Managers. The Greenwood Library Management Collection.

ERIC Educational Resources Information Center

Pitkin, Gary M., Ed.

As a reference guide for library professionals, this volume helps librarians prepare for the future in the growing electronic environment by examining the historical and theoretical background of the National Electronic Library and assessing the role of libraries in the past, present, and future. The book is divided in two sections: "The…

Laboratory x-ray micro-computed tomography: a user guideline for biological samples

PubMed Central

2017-01-01

Abstract Laboratory x-ray micro–computed tomography (micro-CT) is a fast-growing method in scientific research applications that allows for non-destructive imaging of morphological structures. This paper provides an easily operated “how to” guide for new potential users and describes the various steps required for successful planning of research projects that involve micro-CT. Background information on micro-CT is provided, followed by relevant setup, scanning, reconstructing, and visualization methods and considerations. Throughout the guide, a Jackson's chameleon specimen, which was scanned at different settings, is used as an interactive example. The ultimate aim of this paper is make new users familiar with the concepts and applications of micro-CT in an attempt to promote its use in future scientific studies. PMID:28419369

Environmental Issues and Sustainable Futures: A Critical Guide To Recent Books, Reports, and Periodicals. A "Future Survey" Guidebook.

ERIC Educational Resources Information Center

Marien, Michael

This guide seeks to sort the flood of information written about environmental issues and sustainable societies in recent years and order it in some way. A total of 450 document abstracts are presented here, most of which are on books and think tank reports. These items first appeared in "Future Survey" (journal) and were published…

Optimization Strategies for Sensor and Actuator Placement

NASA Technical Reports Server (NTRS)

Padula, Sharon L.; Kincaid, Rex K.

1999-01-01

This paper provides a survey of actuator and sensor placement problems from a wide range of engineering disciplines and a variety of applications. Combinatorial optimization methods are recommended as a means for identifying sets of actuators and sensors that maximize performance. Several sample applications from NASA Langley Research Center, such as active structural acoustic control, are covered in detail. Laboratory and flight tests of these applications indicate that actuator and sensor placement methods are effective and important. Lessons learned in solving these optimization problems can guide future research.

Quick Tips Guide for Small Manufacturing Businesses

EPA Pesticide Factsheets

Small manufacturing businesses can use this Quick Tips Guide to be better prepared for future extreme weather events. This guide discusses keeping good records, improving housekeeping procedures, and training employees.

Futures in Business. Interim Guide.

ERIC Educational Resources Information Center

Manitoba Dept. of Education and Training, Winnipeg.

This guide is designed for use by instructors teaching a six-unit course on futures in business. Presented first is a diagram illustrating the place of the course in Manitoba's business education curriculum. The academic, personal management, and teamwork skills that have been deemed critical employability skills required of the Canadian work…

Clean access, measurement, and sampling of Ellsworth Subglacial Lake: A method for exploring deep Antarctic subglacial lake environments

NASA Astrophysics Data System (ADS)

Siegert, Martin J.; Clarke, Rachel J.; Mowlem, Matt; Ross, Neil; Hill, Christopher S.; Tait, Andrew; Hodgson, Dominic; Parnell, John; Tranter, Martyn; Pearce, David; Bentley, Michael J.; Cockell, Charles; Tsaloglou, Maria-Nefeli; Smith, Andy; Woodward, John; Brito, Mario P.; Waugh, Ed

2012-01-01

Antarctic subglacial lakes are thought to be extreme habitats for microbial life and may contain important records of ice sheet history and climate change within their lake floor sediments. To find whether or not this is true, and to answer the science questions that would follow, direct measurement and sampling of these environments are required. Ever since the water depth of Vostok Subglacial Lake was shown to be >500 m, attention has been given to how these unique, ancient, and pristine environments may be entered without contamination and adverse disturbance. Several organizations have offered guidelines on the desirable cleanliness and sterility requirements for direct sampling experiments, including the U.S. National Academy of Sciences and the Scientific Committee on Antarctic Research. Here we summarize the scientific protocols and methods being developed for the exploration of Ellsworth Subglacial Lake in West Antarctica, planned for 2012-2013, which we offer as a guide to future subglacial environment research missions. The proposed exploration involves accessing the lake using a hot-water drill and deploying a sampling probe and sediment corer to allow sample collection. We focus here on how this can be undertaken with minimal environmental impact while maximizing scientific return without compromising the environment for future experiments.

The future of image-guided radiotherapy will be MR guided

PubMed Central

Wen, Zhifei; Sadagopan, Ramaswamy; Wang, Jihong; Ibbott, Geoffrey S

2017-01-01

Advances in image-guided radiotherapy (RT) have allowed for dose escalation and more precise radiation treatment delivery. Each decade brings new imaging technologies to help improve RT patient setup. Currently, the most frequently used method of three-dimensional pre-treatment image verification is performed with cone beam CT. However, more recent developments have provided RT with the ability to have on-board MRI coupled to the teleradiotherapy unit. This latest tool for treating cancer is known as MR-guided RT. Several varieties of these units have been designed and installed in centres across the globe. Their prevalence, history, advantages and disadvantages are discussed in this review article. In preparation for the next generation of image-guided RT, this review also covers where MR-guided RT might be heading in the near future. PMID:28256898

Research Performed within the Non-Destructive Evaluation Team at NASA Glenn Research Center

NASA Technical Reports Server (NTRS)

Burns, Erin A.

2004-01-01

Non-destructive testing is essential in many fields of manufacturing and research in order to perform reliable examination of potentially damaged materials and parts without destroying the inherent structure of the materials. Thus, the Non-Destructive Evaluation (NDE) Team at NASA Glenn Research Center partakes in various projects to improve materials testing equipment as well as analyze materials, material defects, and material deficiencies. Due to the array of projects within the NDE Team at this time, five research aims were supplemental to some current projects. A literature survey of "DE and testing methodologies as related to rocks was performed. Also, Mars Expedition Rover technology was assessed to understand the requirements for instrumentation in harsh space environments (e.g. temperature). Potential instrumentation and technologies were also considered and documented. The literature survey provided background and potential sources for a proposal to acquire funding for ultrasonic instrumentation on board a future Mars expedition. The laboratory uses a Santec Systems AcousticScope AS200 acoustography system. Labview code was written within the current program in order to improve the current performance of the acoustography system. A sample of Reinforced Carbon/Carbon (RCC) material from the leading edge of the space shuttle underwent various non-destructive tests (guided wave scanning, thermography, computed tomography, real time x-ray, etc.) in order to characterize its structure and examine possible defects. Guided wave scan data of a ceramic matrix composite (CMC) panel was reanalyzed utilizing image correlations and signal processing variables. Additional guided wave scans and thermography were also performed on the CMC panel. These reevaluated data and images will be used in future presentations and publications. An additional axis for the guided wave scanner was designed, constructed, and implemented. This additional axis allowed incremental spacing of the previously fixed transducers for ultrasonic velocity measurements.

The use of virtual reality in the study, assessment, and treatment of body image in eating disorders and nonclinical samples: a review of the literature.

PubMed

Ferrer-García, Marta; Gutiérrez-Maldonado, José

2012-01-01

This article reviews research into the use of virtual reality in the study, assessment, and treatment of body image disturbances in eating disorders and nonclinical samples. During the last decade, virtual reality has emerged as a technology that is especially suitable not only for the assessment of body image disturbances but also for its treatment. Indeed, several virtual environment-based software systems have been developed for this purpose. Furthermore, virtual reality seems to be a good alternative to guided imagery and in vivo exposure, and is therefore very useful for studies that require exposure to life-like situations but which are difficult to conduct in the real world. Nevertheless, review highlights the lack of published controlled studies and the presence of methodological drawbacks that should be considered in future studies. This article also discusses the implications of the results obtained and proposes directions for future research. Copyright © 2011 Elsevier Ltd. All rights reserved.

Jobs for the Future.

ERIC Educational Resources Information Center

Business and Professional Women's Foundation, Washington, DC.

This guide is intended to assist women in selecting and preparing for occupations that will either be in demand or continue to be in demand in the future. The first part is a guide to evaluating an occupation. It covers the following topics: costs and benefits (skills needed, training requirements, availability of training, costs of training,…

Future Aspiring Aviators, Primary: An Aviation Curriculum Guide K-3

DOT National Transportation Integrated Search

1995-01-01

Prepared ca. 1995. The Federal Aviation Administration is pleased to present the Aviation Education Teacher's Guide Series. The series includes four publications specifically designed as resources to those interested in aviation education. The guides...

Finland on a road towards a modern legal biobanking infrastructure.

PubMed

Soini, Sirpa

2013-06-01

Finland has enacted a Biobank Act that will come into force on 1 September 2013. Finland is regarded as a highly successful environment for medical research using population samples and data for many reasons. One of the rationales behind the new legislation was to solve the problems due to the overly strict informed consent doctrine hindering access to old samples and data and asking for multi-purpose consents. Yet although consent is the primary justification to use biobank samples and data, the Biobank Act allows asking for a consent for several unspecified future research purposes. The guiding principles of the Biobank Act are promotion of trust, equal access to data and samples, protection of privacy, acceleration of innovation activities, and bringing biobank activities under public scrutiny. To the author's knowledge, this is the first "all purpose" Biobank Act in Europe applied to all biobanks in one country.

MRI/US fusion-guided prostate biopsy allows for equivalent cancer detection with significantly fewer needle cores in biopsy-naive men

PubMed Central

Yarlagadda, Vidhush K.; Lai, Win Shun; Gordetsky, Jennifer B.; Porter, Kristin K.; Nix, Jeffrey W.; Thomas, John V.; Rais-Bahrami, Soroush

2018-01-01

PURPOSE We aimed to investigate the efficiency and cancer detection of magnetic resonance imaging (MRI)/ultrasonography (US) fusion-guided prostate biopsy in a cohort of biopsy-naive men compared with standard-of-care systematic extended sextant transrectal ultrasonography (TRUS)-guided biopsy. METHODS From 2014 to 2016, 72 biopsy-naive men referred for initial prostate cancer evaluation who underwent MRI of the prostate were prospectively evaluated. Retrospective review was performed on 69 patients with lesions suspicious for malignancy who underwent MRI/US fusion-guided biopsy in addition to systematic extended sextant biopsy. Biometric, imaging, and pathology data from both the MRI-targeted biopsies and systematic biopsies were analyzed and compared. RESULTS There were no significant differences in overall prostate cancer detection when comparing MRI-targeted biopsies to standard systematic biopsies (P = 0.39). Furthermore, there were no significant differences in the distribution of severity of cancers based on grade groups in cases with cancer detection (P = 0.68). However, significantly fewer needle cores were taken during the MRI/US fusion-guided biopsy compared with systematic biopsy (63% less cores sampled, P < 0.001) CONCLUSION In biopsy-naive men, MRI/US fusion-guided prostate biopsy offers equal prostate cancer detection compared with systematic TRUS-guided biopsy with significantly fewer tissue cores using the targeted technique. This approach can potentially reduce morbidity in the future if used instead of systematic biopsy without sacrificing the ability to detect prostate cancer, particularly in cases with higher grade disease. PMID:29770762

TELECOM 2000: An Exploration of the Long-Term Development of Telecommunications in Australia.

ERIC Educational Resources Information Center

Australian Telecommunications Commission, Melbourne.

This document is intended as a guide to directions in Australia's social, economic, and technical future as related to likely trends in the demand for telecommunication facilities in the early Twenty-First Century. From this exploration of the future of telecommunications, nine policy recommendations were made to guide telecommunication research,…

Passive PE Sampling in Support of In Situ Remediation of Contaminated Sediments - Passive Sampler PRC Calculation Software User’s Guide

DTIC Science & Technology

2014-07-01

different value and pressing Enter. The PRC- Calc session can be saved for future use with these new values using the Save Session button in the upper...describe (a) how the PRC Correction Calculator (PRC- Calc ) uses the model of Fernandez et al. (2009), (b) how well its performance compares against...experimental data, (c) how the user may prepare their computer with software to use the PRC calculator, and then (d) how to use PRC- Calc to process PRC

A Robust Framework for Microbial Archaeology

PubMed Central

Warinner, Christina; Herbig, Alexander; Mann, Allison; Yates, James A. Fellows; Weiβ, Clemens L.; Burbano, Hernán A.; Orlando, Ludovic; Krause, Johannes

2017-01-01

Microbial archaeology is flourishing in the era of high-throughput sequencing, revealing the agents behind devastating historical plagues, identifying the cryptic movements of pathogens in prehistory, and reconstructing the ancestral microbiota of humans. Here, we introduce the fundamental concepts and theoretical framework of the discipline, then discuss applied methodologies for pathogen identification and microbiome characterization from archaeological samples. We give special attention to the process of identifying, validating, and authenticating ancient microbes using high-throughput DNA sequencing data. Finally, we outline standards and precautions to guide future research in the field. PMID:28460196

Human Skeletal Muscle Health with Spaceflight

NASA Astrophysics Data System (ADS)

Trappe, Scott

2012-07-01

This lecture will overview the most recent aerobic and resistance exercise programs used by crewmembers while aboard the International Space Station (ISS) for six months and examine its effectiveness for protecting skeletal muscle health. Detailed information on the exercise prescription program, whole muscle size, whole muscle performance, and cellular data obtained from muscle biopsy samples will be presented. Historically, detailed information on the exercise program while in space has not been available. These most recent exercise and muscle physiology findings provide a critical foundation to guide the exercise countermeasure program forward for future long-duration space missions.

Teens Working: Turning Earning into Learning. Facilitator Guide [and] Critical Workplace Issues [and] Student Guide.

ERIC Educational Resources Information Center

Northwest Regional Educational Lab., Portland, OR. Education, Career, and Community Program.

These guides are part of a toolkit designed to help young people make connections between the jobs they now hold, the classes they are taking, and the goals they may have for the near and distant future. The guides contain a variety of materials and activities appropriate for all skill levels. The activities in the student guide are grounded in…

In Situ Biological Contamination Studies of the Moon: Implications for Future Planetary Protection and Life Detection Missions

NASA Technical Reports Server (NTRS)

Glavin, Daniel P.; Dworkin, Jason P.; Lupisella, Mark; Kminek, Gerhard; Rummel, John D.

2010-01-01

NASA and ESA have outlined visions for solar system exploration that will include a series of lunar robotic precursor missions to prepare for, and support a human return to the Moon, and future human exploration of Mars and other destinations. One of the guiding principles for exploration is to pursue compelling scientific questions about the origin and evolution of life. The search for life on objects such as Mars will require that all spacecraft and instrumentation be sufficiently cleaned and sterilized prior to launch to ensure that the scientific integrity of extraterrestrial samples is not jeopardized by terrestrial organic contamination. Under the Committee on Space Research's (COSPAR's) current planetary protection policy for the Moon, no sterilization procedures are required for outbound lunar spacecraft, nor is there yet a planetary protection category for human missions. Future in situ investigations of a variety of locations on the Moon by highly sensitive instruments designed to search for biologically derived organic compounds would help assess the contamination of the Moon by lunar spacecraft. These studies could also provide valuable "ground truth" data for Mars sample return missions and help define planetary protection requirements for future Mars bound spacecraft carrying life detection experiments. In addition, studies of the impact of terrestrial contamination of the lunar surface by the Apollo astronauts could provide valuable data to help refine future Mars surface exploration plans for a human mission to Mars.

A practical guide to value of information analysis.

PubMed

Wilson, Edward C F

2015-02-01

Value of information analysis is a quantitative method to estimate the return on investment in proposed research projects. It can be used in a number of ways. Funders of research may find it useful to rank projects in terms of the expected return on investment from a variety of competing projects. Alternatively, trialists can use the principles to identify the efficient sample size of a proposed study as an alternative to traditional power calculations, and finally, a value of information analysis can be conducted alongside an economic evaluation as a quantitative adjunct to the 'future research' or 'next steps' section of a study write up. The purpose of this paper is to present a brief introduction to the methods, a step-by-step guide to calculation and a discussion of issues that arise in their application to healthcare decision making. Worked examples are provided in the accompanying online appendices as Microsoft Excel spreadsheets.

School of the Future Handbook. A Guide for Technology Implementation. F. M. Black Middle School.

ERIC Educational Resources Information Center

Smith, Richard Alan; Sassi, Anthony

In 1985, Apple Computer, Inc., and the Houston Independent School District began a project to create a model School of the Future at the F. M. Black Middle School. As described in this guide, the project was designed to demonstrate how microcomputers and related technology can make the process of instruction more efficient and effective. The…

A Policymaker's Guide to Early College Designs: Expanding a Strategy for Achieving College Readiness for All

ERIC Educational Resources Information Center

Hoffman, Nancy; Vargas, Joel

2010-01-01

Today, states and the federal government recognize the potential of early college designs to improve the economic prospects of future generations. But individuals are just beginning to put in place public policies that promote and support early college designs on a significant scale. Jobs for the Future (JFF) prepared this guide to help…

A Framework for Guiding Future Citizens to Think Critically about Nature of Science and Socioscientific Issues

ERIC Educational Resources Information Center

Yacoubian, Hagop A.

2015-01-01

In this article, I introduce a framework for guiding future citizens to think critically about nature of science (NOS) and "with" NOS as they engage in socioscientific decision making. The framework, referred to as the critical thinking--nature of science (CT-NOS) framework, explicates and targets both NOS as a learning objective and NOS…

Fidelity in Models-Based Practice Research in Sport Pedagogy: A Guide for Future Investigations

ERIC Educational Resources Information Center

Hastie, Peter A.; Casey, Ashley

2014-01-01

This paper provides a commentary on research on models-based practice within physical education and presents a tutorial that aims to guide the reporting of future research using pedagogical models. Three key elements are presented that could be considered as essential for inclusion in any methods section in order for readers to gain an accurate…

Learning, techniques, and complications of endoscopic ultrasound (EUS)-guided sampling in gastroenterology: European Society of Gastrointestinal Endoscopy (ESGE) Technical Guideline.

PubMed

Polkowski, M; Larghi, A; Weynand, B; Boustière, C; Giovannini, M; Pujol, B; Dumonceau, J-M

2012-02-01

This article is the second of a two-part publication that expresses the current view of the European Society of Gastrointestinal Endoscopy (ESGE) about endoscopic ultrasound (EUS)-guided sampling, including EUS-guided fine needle aspiration (EUS-FNA) and EUS-guided Trucut biopsy. The first part (the Clinical Guideline) focused on the results obtained with EUS-guided sampling, and the role of this technique in patient management, and made recommendations on circumstances that warrant its use. The current Technical Guideline discusses issues related to learning, techniques, and complications of EUS-guided sampling, and to processing of specimens. Technical issues related to maximizing the diagnostic yield (e.g., rapid on-site cytopathological evaluation, needle diameter, microcore isolation for histopathological examination, and adequate number of needle passes) are discussed and recommendations are made for various settings, including solid and cystic pancreatic lesions, submucosal tumors, and lymph nodes. The target readership for the Clinical Guideline mostly includes gastroenterologists, oncologists, internists, and surgeons while the Technical Guideline should be most useful to endoscopists who perform EUS-guided sampling. A two-page executive summary of evidence statements and recommendations is provided. © Georg Thieme Verlag KG Stuttgart · New York.

A Systematic Review of Relaxation, Meditation, and Guided Imagery Strategies for Symptom Management in Heart Failure.

PubMed

Kwekkeboom, Kristine L; Bratzke, Lisa C

2016-01-01

Pain, dyspnea, fatigue, and sleep disturbance are prevalent and distressing symptoms in persons with advanced heart failure. Although many lifestyle and self-care interventions have been developed to control heart failure progression, very few studies have explored treatments exclusively for symptom palliation. Cognitive-behavioral strategies may be effective treatment for these symptoms in advanced heart failure. A systemic review was conducted to describe the effect of cognitive-behavioral strategies on pain, dyspnea, fatigue, and sleep disturbance in patients with heart failure. CINAHL, Medline, and PsychINFO were searched from inception through December 2014. Articles were selected for inclusion if they tested a cognitive-behavioral strategy using a quasi-experimental or experimental design, involved a sample of adults with heart failure, and measured pain, dyspnea, fatigue, sleep disturbance, or symptom-related quality of life. The 2 authors evaluated study quality, abstracted data elements from each study, and synthesized findings. Thirteen articles describing 9 unique studies met criteria and were included in the review. Five studies tested relaxation strategies, 3 tested meditation strategies, and 1 tested a guided imagery strategy. Of the 9 studies, 7 demonstrated some improvement in symptom outcomes. Relaxation, meditation, guided imagery, or combinations of these strategies resulted in less dyspnea and better sleep compared with attention control or usual care conditions and reduced pain, dyspnea, fatigue, and sleep disturbance within treatment groups (pretreatment to posttreatment). Symptom-related quality of life was improved with meditation compared with attention control and usual care conditions and improved pre- to post-guided imagery. Studies exploring cognitive-behavioral symptom management strategies in heart failure vary in quality and report mixed findings but indicate potential beneficial effects of relaxation, meditation, and guided imagery on heart failure-related symptoms. Future research should test cognitive-behavioral strategies in rigorously designed efficacy trials, using samples selected for their symptom experience, and measure pain, dyspnea, fatigue, and sleep disturbance outcomes with targeted symptom measures.

A Systematic Review of Relaxation, Meditation, and Guided Imagery Strategies for Symptom Management in Heart Failure

PubMed Central

Kwekkeboom, Kristine L.; Bratzke, Lisa C.

2015-01-01

Background Pain, dyspnea, fatigue, and sleep disturbance are prevalent and distressing symptoms in persons with advanced heart failure. Although many lifestyle and self-care interventions have been developed to control heart failure progression, very few studies have explored treatments exclusively for symptom palliation. Cognitive-behavioral strategies may be effective treatment for these symptoms in advanced heart failure. Objective A systemic review was conducted to describe the effect of cognitive-behavioral strategies on pain, dyspnea, fatigue, and sleep disturbance in patients with heart failure. Methods CINAHL, Medline, and PsychINFO were searched from inception through December 2014. Articles were selected for inclusion if they tested a cognitive-behavioral strategy using a quasi-experimental or experimental design, involved a sample of adults with heart failure, and measured pain, dyspnea, fatigue, sleep disturbance, or symptom-related quality of life (QoL). The two authors evaluated study quality, abstracted data elements from each study, and synthesized findings. Results Thirteen articles describing nine unique studies met criteria and were included in the review. Five studies tested relaxation strategies, three tested meditation strategies, and one tested a guided imagery strategy. Seven of the nine studies demonstrated some improvement in symptom outcomes. Relaxation, meditation, guided imagery, or combinations of these strategies resulted in less dyspnea and better sleep compared to attention control or usual care conditions, and reduced pain, dyspnea, fatigue and sleep disturbance within treatment groups (pre- to post-treatment). Symptom-related QoL was improved with meditation compared to attention control and usual care conditions, and improved pre- to post-guided imagery. Conclusions Studies exploring cognitive-behavioral symptom management strategies in heart failure vary in quality and report mixed findings, but indicate potential beneficial effects of relaxation, meditation, and guided imagery on heart failure-related symptoms. Future research should test cognitive-behavioral strategies in rigorously designed efficacy trials, using samples selected for their symptom experience, and measure pain, dyspnea, fatigue, and sleep disturbance outcomes with targeted symptom measures. PMID:26065388

The Effect of Guided Care Teams on the Use of Health Services

PubMed Central

Boult, Chad; Reider, Lisa; Leff, Bruce; Frick, Kevin D.; Boyd, Cynthia M.; Wolff, Jennifer L.; Frey, Katherine; Karm, Lya; Wegener, Stephen T.; Mroz, Tracy; Scharfstein, Daniel O.

2015-01-01

Background The effect of interdisciplinary primary care teams on the use of health services by patients with multiple chronic conditions is uncertain. This study aimed to measure the effect of guided care teams on multimorbid older patients’ use of health services. Methods Eligible patients from 3 health care systems in the Baltimore, Maryland–Washington, DC, area were cluster-randomized to receive guided care or usual care for 20 months between November 1, 2006, and June 30, 2008. Eight services of a guided care nurse working in partnership with patients’ primary care physicians were provided: comprehensive assessment, evidence-based care planning, monthly monitoring of symptoms and adherence, transitional care, coordination of health care professionals, support for self-management, support for family caregivers, and enhanced access to community services. Outcome measures were frequency of use of emergency departments, hospitals, skilled nursing facilities, home health agencies, primary care physician services, and specialty physician services. Results The study included 850 older patients at high risk for using health care heavily in the future. The only statistically significant overall effect of guided care in the whole sample was a reduction in episodes of home health care (odds ratio, 0.70; 95% confidence interval, 0.53–0.93). In a preplanned analysis, guided care also reduced skilled nursing facility admissions (odds ratio, 0.53; 95% confidence interval,0.31–0.89) and days (0.48; 0.28–0.84) among Kaiser-Permanente patients. Conclusions Guided care reduces the use of home health care but has little effect on the use of other health services in the short run. Its positive effect on Kaiser-Permanente patients’ use of skilled nursing facilities and other health services is intriguing. Trial Registration clinicaltrials.gov Identifier: NCT00121940 PMID:21403043

Achievable future conditions as a framework for guiding forest conservation and management

Treesearch

S.W. Golladay; K.L. Martin; J. M. Vose; D. N. Wear; A.P. Covich; R.J. Hobbs; Kier Klepzig; G.E. Likens; R.J. Naiman; A.W. Shearer

2016-01-01

We contend that traditional approaches to forest conservation and management will be inadequate given the predicted scale of social-economic and biophysical changes in the 21st century. New approaches, focused on anticipating and guiding ecological responses to change, are urgently needed to ensure the full value of forest ecosystem services for future generations....

Shaping up Your Financial Future, Grades 6-8. Teacher Guide [and] Student Workouts. Financial Fitness for Life.

ERIC Educational Resources Information Center

Flowers, Barbara; Gallaher, Sheryl Szot

Middle school students enjoy personal finance because it involves making decisions about their lives, both in the present and in the future. This teacher's guide and student workouts package consists of 17 economics lessons for students at grades 6-8 that are divided into 5 theme areas: the economic way of thinking; earning an income; saving;…

Futuring for Future Ready Librarians

ERIC Educational Resources Information Center

Figueroa, Miguel A.

2018-01-01

Futurists and foresight professionals offer several guiding principles for thinking about the future. These principles can help people to think about the future and become more powerful players in shaping the preferred futures they want for themselves and their communities. The principles also fit in well as strategies to support the Future Ready…

Arsenic contamination of drinking water in Ireland: A spatial analysis of occurrence and potential risk.

PubMed

McGrory, Ellen R; Brown, Colin; Bargary, Norma; Williams, Natalya Hunter; Mannix, Anthony; Zhang, Chaosheng; Henry, Tiernan; Daly, Eve; Nicholas, Sarah; Petrunic, Barbara M; Lee, Monica; Morrison, Liam

2017-02-01

The presence of arsenic in groundwater has become a global concern due to the health risks from drinking water with elevated concentrations. The Water Framework Directive (WFD) of the European Union calls for drinking water risk assessment for member states. The present study amalgamates readily available national and sub-national scale datasets on arsenic in groundwater in the Republic of Ireland. However, due to the presence of high levels of left censoring (i.e. arsenic values below an analytical detection limit) and changes in detection limits over time, the application of conventional statistical methods would inhibit the generation of meaningful results. In order to handle these issues several arsenic databases were integrated and the data modelled using statistical methods appropriate for non-detect data. In addition, geostatistical methods were used to assess principal risk components of elevated arsenic related to lithology, aquifer type and groundwater vulnerability. Geographic statistical methods were used to overcome some of the geographical limitations of the Irish Environmental Protection Agency (EPA) sample database. Nearest-neighbour inverse distance weighting (IDW) and local indicator of spatial association (LISA) methods were used to estimate risk in non-sampled areas. Significant differences were also noted between different aquifer lithologies, indicating that Rhyolite, Sandstone and Shale (Greywackes), and Impure Limestone potentially presented a greater risk of elevated arsenic in groundwaters. Significant differences also occurred among aquifer types with poorly productive aquifers, locally important fractured bedrock aquifers and regionally important fissured bedrock aquifers presenting the highest potential risk of elevated arsenic. No significant differences were detected among different groundwater vulnerability groups as defined by the Geological Survey of Ireland. This research will assist management and future policy directions of groundwater resources at EU level and guide future research focused on understanding arsenic mobilisation processes to facilitate in guiding future development, testing and treatment requirements of groundwater resources. Copyright © 2016 Elsevier B.V. All rights reserved.

Photoacoustic image-guided navigation system for surgery (Conference Presentation)

NASA Astrophysics Data System (ADS)

Park, Sara; Jang, Jongseong; Kim, Jeesu; Kim, Young Soo; Kim, Chulhong

2017-03-01

Identifying and delineating invisible anatomical and pathological details during surgery guides surgical procedures in real time. Various intraoperative imaging modalities have been increasingly employed to minimize such surgical risks as anatomical changes, damage to normal tissues, and human error. However, current methods provide only structural information, which cannot identify critical structures such as blood vessels. The logical next step is an intraoperative imaging modality that can provide functional information. Here, we have successfully developed a photoacoustic (PA) image-guided navigation system for surgery by integrating a position tracking system and a real-time clinical photoacoustic/ultrasound (PA/US) imaging system. PA/US images were acquired in real time and overlaid on pre-acquired cross-sectional magnetic resonance (MR) images. In the overlaid images, PA images represent the optical absorption characteristics of the surgical field, while US and MR images represent the morphological structure of surrounding tissues. To test the feasibility of the system, we prepared a tissue mimicking phantom which contained two samples, methylene blue as a contrast agent and water as a control. We acquired real-time overlaid PA/US/MR images of the phantom, which were well-matched with the optical and morphological properties of the samples. The developed system is the first approach to a novel intraoperative imaging technology based on PA imaging, and we believe that the system can be utilized in various surgical environments in the near future, improving the efficacy of surgical guidance.

[Guided and computer-assisted implant surgery and prosthetic: The continuous digital workflow].

PubMed

Pascual, D; Vaysse, J

2016-02-01

New continuous digital workflow protocols of guided and computer-assisted implant surgery improve accuracy of implant positioning. The design of the future prosthesis is based on the available prosthetic space, gingival height and occlusal relationship with the opposing and adjacent teeth. The implant position and length depend on volume, density and bone quality, gingival height, tooth-implant and implant-implant distances, implant parallelism, axis and type of the future prosthesis. The crown modeled on the software will therefore serve as a guide to the future implant axis and not the reverse. The guide is made by 3D printing. The software determines surgical protocol with the drilling sequences. The unitary or plural prosthesis, modeled on the software and built before surgery, is loaded directly after implant placing, if needed. These protocols allow for a full continuity of the digital workflow. The software provides the surgeon and the dental technician a total freedom for the prosthetic-surgery guide design and the position of the implants. The prosthetic project, occlusal and aesthetic, taking the bony and surgical constraints into account, is optimized. The implant surgery is simplified and becomes less "stressful" for the patient and the surgeon. Guided and computer-assisted surgery with continuous digital workflow is becoming the technique of choice to improve the accuracy and quality of implant rehabilitation. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Design and construction of a multiple beam laser projector and dynamically refocused wavefront sensor

NASA Astrophysics Data System (ADS)

Stalcup, Thomas Eugene, Jr.

Adaptive optics using natural guide stars can produce images of amazing quality, but is limited to a small fraction of the sky due to the need for a relatively bright guidestar. Adaptive optics systems using a laser generated artificial reference can be used over a majority of the sky, but these systems have some attendant problems. These problems can be reduced by increasing the altitude of the laser return, and indeed a simple, single laser source focused at an altitude of 95 km on a layer of atmospheric sodium performs well for the current generation of 8--10 m telescopes. For future giant telescopes in the 20--30 m class, however, the errors due to incorrect atmospheric sampling and spot elongation will prohibit such a simple system from working. The system presented in this dissertation provides a solution to these problems. Not only does it provide the 6.5m MMT with a relatively inexpensive laser guide star system with unique capabilities, it allows research into solving many of the problems faced by laser guide star systems on future giant telescopes. The MMT laser guidestar system projects a constellation of five doubled Nd:YAG laser beams focused at a mean height of 25 km, with a dynamic refocus system that corrects for spot elongation and allows integrating the return from a 10 km long range gate. It has produced seeing limited spot sizes in ˜1 arcsecond seeing conditions, and has enabled the first on-sky results of Ground Layer Adaptive Optics (GLAO).

Guided transect sampling - a new design combining prior information and field surveying

Treesearch

Anna Ringvall; Goran Stahl; Tomas Lamas

2000-01-01

Guided transect sampling is a two-stage sampling design in which prior information is used to guide the field survey in the second stage. In the first stage, broad strips are randomly selected and divided into grid-cells. For each cell a covariate value is estimated from remote sensing data, for example. The covariate is the basis for subsampling of a transect through...

Home Economics Education Career Path Guide and Model Curriculum Standards.

ERIC Educational Resources Information Center

California State Univ., Northridge.

This curriculum guide developed in California and organized in 10 chapters, provides a home economics education career path guide and model curriculum standards for high school home economics programs. The first chapter contains information on the following: home economics education in California, home economics careers for the future, home…

Nutrition and Food Science. Teacher's Instructional Guide.

ERIC Educational Resources Information Center

Hays, Tricia

This teaching, guide for a high school nutrition and food science course, includes introductory information about the course, course design, facilities and equipment, Future Homemakers of America, and use of the guide. The course addresses nutrition and food science from the perspective of food habits and wellness; menu planning; special dietary…

Confronting Global Issues: A Multipurpose IR Simulation

ERIC Educational Resources Information Center

Shellman, Stephen M.; Turan, Kursad

2006-01-01

This article describes an international relations simulation that focuses on threats of transnational insurgent organizations, the future of the Iraqi regime, and the effect of globalization on foreign policies. It contains both the Simulation Director's Guide and the Participant's Guide. The guides explain the steps taken to run the simulation…

Kansas Business Education Curriculum Guide.

ERIC Educational Resources Information Center

Groneman, Nancy; Owen, Susan

This curriculum guide was developed to help business education teachers in Kansas improve and update their curricula to meet the needs of the present and future electronic office. The guide is based upon the premise that computer and keyboarding skills will be needed by all students and that communication skills and knowledge of word…

Patterns of fish assemblage structure and habitat use among main- and side-channel environments in the lower Kootenai River, Idaho

USGS Publications Warehouse

Watkins, Carson J.; Stevens, Bryan S.; Quist, Michael C.; Shepard, Bradley B.; Ireland, Susan C.

2015-01-01

The lower Kootenai River, Idaho, was sampled during the summers of 2012 and 2013 to evaluate its fish assemblage structure at seven sites within main- and side-channel habitats where large-scale habitat rehabilitation was undertaken. Understanding the current patterns of fish assemblage structure and their relationships with habitat is important for evaluating the effects of past and future rehabilitation projects on the river. Species-specific habitat associations were modeled, and the variables that best explained the occurrence and relative abundance of fish were identified in order to guide future habitat rehabilitation so that it benefits native species. The results indicated that the side-channel habitats supported higher species richness than the main-channel habitats and that nonnative fishes were closely associated with newly rehabilitated habitats. This research provides valuable insight on the current fish assemblages in the Kootenai River and the assemblage-level responses that may occur as a result of future rehabilitation activities.

Developing iCare v.1.0: an academic electronic health record.

PubMed

Wyatt, Tami H; Li, Xueping; Indranoi, Chayawat; Bell, Matthew

2012-06-01

An electronic health record application, iCare v.1.0, was developed and tested that allows data input and retrieval while tracking student performance over time. The development and usability testing of iCare v.1.0 followed a rapid prototyping software development and testing model. Once the functionality was tested by engineers, the usability and feasibility testing began with a convenience sample of focus group members including undergraduate and graduate students and faculty. Three focus groups were created, and four subjects participated in each focus group (n = 12). Nielsen's usability heuristics and methods of evaluation were used to evaluate data captured from each focus group. Overall, users wanted a full-featured electronic health record with features that coached or guided users. The earliest versions of iCare v.1.0 did not provide help features and prompts to guide students but were later added. Future versions will incorporate a full-featured help section. The interface and design of iCare v.1.0 are similar to professional electronic health record applications. As a result of this usability study, future versions of iCare will include more robust help features along with advanced reporting and elements specific to specialty populations such as pediatrics and mental health services.

Effect of a supportive-educative nursing intervention on older adults' perceptions of self-care after a stroke.

PubMed

Folden, S L

1993-01-01

The purpose of this study was to test the effects of an individually focused, guided decision-making intervention on individuals' perception of self-care ability following a stroke. A convenience sample of 68 individuals participating in four stroke rehabilitation programs in southeast Florida participated in the study. A quasi-experimental design using a pretest and a posttest was implemented. Findings indicated the potential effectiveness of this intervention in significantly increasing individuals' perceptions of their self-care ability after a stroke. Implications for practice and future research are discussed.

Cross-instrument Analysis Correlation Software

DOE Office of Scientific and Technical Information (OSTI.GOV)

McJunkin, Timothy R.

This program has been designed to assist with the tracking of a sample from one analytical instrument to another such as SEM, microscopes, micro x-ray diffraction and other instruments where particular positions/locations on the sample are examined, photographed, etc. The software is designed to easily enter the position of fiducials and locations of interest such that in a future session in the same of different instrument the positions of interest can be re-found through using the known location fiducials in the current and reference session to transform the point into the current sessions coordinate system. The software is dialog boxmore » driven guiding the user through the necessary data entry and program choices. Information is stored in a series of text based extensible markup language (XML) files.« less

Overcoming Hurdles: Teaching Guides To Interpret Biodiversity Conservation.

ERIC Educational Resources Information Center

Kohl, Jon; Brown, Cynthia; Humke, Matt

2001-01-01

Highlights the development and use of bilingual nature guide training. Examines work at the RARE Center for tropical conservation in Central America. Speculates about the future of conservation interpretation. (DDR)

Transportation Acronym Guide, 1994

DOT National Transportation Integrated Search

1994-11-01

This report compiles and identifies transportation and transportation-related acronyms throughout the Department of Transportation and other related U.S. government agencies. This is the second edition of the Transportation Acronym Guide (TAG); futur...

Transportation Acronym Guide, 1996

DOT National Transportation Integrated Search

1996-06-01

This report compiles and identifies transportation and transportation-related acronyms throughout the Department of Transportation and other related U.S. government agencies. This is the second edition of the Transportation Acronym Guide (TAG); futur...

MAP: an iterative experimental design methodology for the optimization of catalytic search space structure modeling.

PubMed

Baumes, Laurent A

2006-01-01

One of the main problems in high-throughput research for materials is still the design of experiments. At early stages of discovery programs, purely exploratory methodologies coupled with fast screening tools should be employed. This should lead to opportunities to find unexpected catalytic results and identify the "groups" of catalyst outputs, providing well-defined boundaries for future optimizations. However, very few new papers deal with strategies that guide exploratory studies. Mostly, traditional designs, homogeneous covering, or simple random samplings are exploited. Typical catalytic output distributions exhibit unbalanced datasets for which an efficient learning is hardly carried out, and interesting but rare classes are usually unrecognized. Here is suggested a new iterative algorithm for the characterization of the search space structure, working independently of learning processes. It enhances recognition rates by transferring catalysts to be screened from "performance-stable" space zones to "unsteady" ones which necessitate more experiments to be well-modeled. The evaluation of new algorithm attempts through benchmarks is compulsory due to the lack of past proofs about their efficiency. The method is detailed and thoroughly tested with mathematical functions exhibiting different levels of complexity. The strategy is not only empirically evaluated, the effect or efficiency of sampling on future Machine Learning performances is also quantified. The minimum sample size required by the algorithm for being statistically discriminated from simple random sampling is investigated.

Managing Your Money. Leader's Guide [and] Participant's Workbook.

ERIC Educational Resources Information Center

Nieuwenhuis, Ann; Hathaway, Irene

This document contains both a leader's guide and participant's workbook on money management. The leader's and participant's guides contain 10 parts each: (1) danger signs in money management; (2) what's important to you; (3) spending for the future; (4) financial fitness; (5) use credit wisely; (6) decisions, decisions; (7) shopping basics; (8)…

Automated database-guided expert-supervised orientation for immunophenotypic diagnosis and classification of acute leukemia

PubMed Central

Lhermitte, L; Mejstrikova, E; van der Sluijs-Gelling, A J; Grigore, G E; Sedek, L; Bras, A E; Gaipa, G; Sobral da Costa, E; Novakova, M; Sonneveld, E; Buracchi, C; de Sá Bacelar, T; te Marvelde, J G; Trinquand, A; Asnafi, V; Szczepanski, T; Matarraz, S; Lopez, A; Vidriales, B; Bulsa, J; Hrusak, O; Kalina, T; Lecrevisse, Q; Martin Ayuso, M; Brüggemann, M; Verde, J; Fernandez, P; Burgos, L; Paiva, B; Pedreira, C E; van Dongen, J J M; Orfao, A; van der Velden, V H J

2018-01-01

Precise classification of acute leukemia (AL) is crucial for adequate treatment. EuroFlow has previously designed an AL orientation tube (ALOT) to guide towards the relevant classification panel (T-cell acute lymphoblastic leukemia (T-ALL), B-cell precursor (BCP)-ALL and/or acute myeloid leukemia (AML)) and final diagnosis. Now we built a reference database with 656 typical AL samples (145 T-ALL, 377 BCP-ALL, 134 AML), processed and analyzed via standardized protocols. Using principal component analysis (PCA)-based plots and automated classification algorithms for direct comparison of single-cells from individual patients against the database, another 783 cases were subsequently evaluated. Depending on the database-guided results, patients were categorized as: (i) typical T, B or Myeloid without or; (ii) with a transitional component to another lineage; (iii) atypical; or (iv) mixed-lineage. Using this automated algorithm, in 781/783 cases (99.7%) the right panel was selected, and data comparable to the final WHO-diagnosis was already provided in >93% of cases (85% T-ALL, 97% BCP-ALL, 95% AML and 87% mixed-phenotype AL patients), even without data on the full-characterization panels. Our results show that database-guided analysis facilitates standardized interpretation of ALOT results and allows accurate selection of the relevant classification panels, hence providing a solid basis for designing future WHO AL classifications. PMID:29089646

Governance: The Mission Ingredient in Security Cooperation

DTIC Science & Technology

2017-06-09

assistance guiding principle of “do-no-harm,” should be included in the future DOS guidance. Seven do-no-harm lessons include: (1) norms and... principle of “do-no-harm.” 15. SUBJECT TERMS Security cooperation, security assistance, defense institution building, USAID, best practices...foreign assistance guiding principle of “do-no-harm,” should be included in the future DOS guidance. Seven do-no-harm lessons include: (1) norms and

Emergency medical services : agenda for the future

DOT National Transportation Integrated Search

1996-08-01

The purpose of the EMS Agenda for the Future is to determine the most important directions for future EMS development, incorporating input from a broad, multidisciplinary spectrum of EMS stakeholders. This document provides guiding principles for the...

Fiscal Officer Training, 1999-2000. Participant's Guide.

ERIC Educational Resources Information Center

Department of Education, Washington, DC.

This guide is intended for use by participants (college fiscal officers, business officers, bursars, loan managers, etc.) in a two-day workshop on Title IV of the reauthorized Higher Education Act. The guide includes copies of the visual displays used in the workshop, space for individual notes, sample forms, sample computer screens, quizzes, and…

Is it ethical to prevent secondary use of stored biological samples and data derived from consenting research participants? The case of Malawi.

PubMed

Mungwira, Randy G; Nyangulu, Wongani; Misiri, James; Iphani, Steven; Ng'ong'ola, Ruby; Chirambo, Chawanangwa M; Masiye, Francis; Mfutso-Bengo, Joseph

2015-12-02

This paper discusses the contentious issue of reuse of stored biological samples and data obtained from research participants in past clinical research to answer future ethical and scientifically valid research questions. Many countries have regulations and guidelines that guide the use and exportation of stored biological samples and data. However, there are variations in regulations and guidelines governing the reuse of stored biological samples and data in Sub-Saharan Africa including Malawi. The current research ethics regulations and guidelines in Malawi do not allow indefinite storage and reuse of biological samples and data for future unspecified research. This comes even though the country has managed to answer pertinent research questions using stored biological samples and data. We acknowledge the limited technical expertise and equipment unavailable in Malawi that necessitates exportation of biological samples and data and the genuine concern raised by the regulatory authorities about the possible exploitation of biological samples and data by researchers. We also acknowledge that Malawi does not have bio-banks for storing biological samples and data for future research purposes. This creates room for possible exploitation of biological samples and data collected from research participants in primary research projects in Malawi. However, research ethics committees require completion and approval of material transfer agreements and data transfer agreements for biological samples and data collected for research purposes respectively and this requirement may partly address the concern raised by the regulatory authorities. Our concern though is that there is no such requirement for biological samples and data collected from patients for clinical or diagnostic purposes. In conclusion, we propose developing a medical data and material transfer agreement for biological samples and data collected from patients for clinical or diagnostic purposes in both public and private health facilities that may end up in research centers outside Malawi. We also propose revision of the current research ethics regulations and guidelines in Malawi in order to allow secondary use of biological samples and data collected from primary research projects as a way of maximizing the use of collected samples and data. Finally, we call for consultation of all stakeholders within the Malawi research community when regulatory authorities are developing policies that govern research in Malawi.

Motivation of Citizen Scientists Participating in Moon Zoo

NASA Astrophysics Data System (ADS)

Brown, Shanique; Gay, P. L.; Daus, C. S.

2011-01-01

Moon Zoo is an online citizen science project with the aim of providing detailed crater counts for as much of the Moon's surface as possible. In addition to focusing on craters, volunteers are encouraged to remain vigilant for sightings of atypical features which may lead to new discoveries. Volunteers accomplish these tasks by exploring images captured by NASA's Lunar Reconnaissance Orbiter (LRO) which has a resolution of 50cm per pixel. To be successful, Moon Zoo needs to attract and retain a large population of citizen scientists. In this study, we examine the factors motivating Moon Zoo participants who invest many hours exploring these images. In this, the first of a two-phased study, we conducted a qualitative analysis using semi-structured interviews as a means of data collection. A stratified sample of participants was used in an attempt to uncover the driving forces behind decisions to participate from a wide-range of participants. Inquiring and probing questions were asked about factors which led volunteers to Moon Zoo as well as reasons which kept them committed to exploring the Moon's surface through this online portal. Responses were then categorized using a grounded theory approach, and frequency distributions are calculated where appropriate. Aggregate results from these interviews are presented here including the demographics of the sample and motivators as per the content analysis. The information gathered from this phase will be used to guide the development of an online survey to further explore volunteers’ motivation based on the presented classification schemes. The survey will then be used to guide future research and development in the area of citizen science in the field of astronomy. These findings will also be useful in charting new boundaries for future research.

Food Production Worker. Dietetic Support Personnel Training Program.

ERIC Educational Resources Information Center

Barker, Ellen; And Others

This curriculum guide, part of a multi-volume dietetic support personnel training program, consists of materials (15 units) for use in training future food production workers. Covered in the first part of the guide are nutrition in food production and diet therapy. The second part of the guide deals with sanitation and safety in food production.…

Local Libraries: Global Awareness. A Librarian's Guide to Global Programming for a Sustainable Future.

ERIC Educational Resources Information Center

Global Learning, Inc., Union, NJ.

This guide seeks to provide public and school librarians with a variety of practical resources and activities for contributing to the public's understanding of major global trends and relationships that affect local communities. The guide contains four sections geared towards children, young adults, adults, and school settings. The children's…

Learning for the Future: Neighborhood Renewal through Adult and Community Learning. A Guide for Local Authorities.

ERIC Educational Resources Information Center

Merton, Bryan; Turner, Cheryl; Ward, Jane; White, Lenford

This guide is intended to assist managers within England's local authority adult and community education services in supporting neighborhood renewal through adult and community learning (ACL). The guide's overall aim is to promote the skills, knowledge, and understanding that underpin the following items: (1) identification and development of…

Pathways to a Sustainable Future: A Curriculum Guide for Maine Schools Exploring Waste Management Issues.

ERIC Educational Resources Information Center

Chewonki Foundation, Wiscasset, ME.

This action guide is designed to help students and teachers become aware of the concepts and issues of waste management, and to motivate them to action in the classroom, school, home, and community. The guide emphasizes interdisciplinary activities that concentrate on the process of problem solving. Activities are identified by appropriate grade…

Follow-up Care Education and Information: Identifying Cancer Survivors in Need of More Guidance.

PubMed

O'Malley, Denalee M; Hudson, Shawna V; Ohman-Strickland, Pamela A; Bator, Alicja; Lee, Heather S; Gundersen, Daniel A; Miller, Suzanne M

2016-03-01

Cancer survivors engage in cancer screenings and protective health behaviors at suboptimal rates despite their increased risk for future illness. Survivorship care plans and other educational strategies to prepare cancer survivors to adopt engaged roles in managing long-term follow-up care and health risks are needed. In a sample of cancer survivors, we identified patient characteristics and psychosocial predictors associated with increased follow-up care informational needs. Cross-sectional surveys were administered to early-stage breast and prostate survivors (N = 278; 68 % breast) at least 2 years post treatment from four community hospital programs in New Jersey between May 2012 and July 2013. Patient demographics, medical history, psychosocial characteristics (i.e., worries about the future, fear of disease recurrence, and patient activation), and perceptions of oncology and primary care were assessed. African-American survivors (AOR = 2.69, 95 % confidence interval [CI] 1.27-5.68) and survivors with higher comorbidity (AOR =1.16, CI 1.01-1.33) were more likely to want additional information to guide follow-up care. Adjusting for race and comorbidities, survivors who wanted more information to guide their follow-up care reported greater worries about the future (p < 0.05) and fears about disease recurrence (p < 0.05) compared to those who did not want additional information. Results emphasize the need to develop cancer survivorship educational strategies that are both responsive to the needs of specific populations (e.g., African-American survivors and patients with multiple comorbidities) and the psychosocial profiles that motivate requests for more extensive follow-up guidance.

Follow-up Care Education and Information: Identifying Cancer Survivors in Need of More Guidance

PubMed Central

O’Malley, Denalee M.; Hudson, Shawna V.; Ohman-Strickland, Pamela A; Bator, Alicja; Lee, Heather S.; Gundersen, Daniel A.; Miller, Suzanne M.

2015-01-01

Background Cancer survivors engage in cancer screenings and protective health behaviors at suboptimal rates despite their increased risk for future illness. Survivorship care plans and other educational strategies to prepare cancer survivors to adopt engaged roles in managing long-term follow-up care and health risks are needed. In a sample of cancer survivors, we identified patient characteristics and psychosocial predictors associated with increased follow-up care informational needs. Methods Cross-sectional surveys were administered to early stage breast and prostate survivors (N=278; 68% breast) at least two years post-treatment from four community hospital programs in New Jersey between May 2012-July 2013. Patient demographics, medical history, psychosocial characteristics (i.e., worries about the future, fear of disease recurrence, and patient activation) and perceptions of oncology and primary care were assessed. Results African American survivors (AOR =2.69, 95% confidence interval [CI] 1.27–5.68) and survivors with higher comorbidity (AOR=1.16, CI 1.01–1.33) were more likely to want additional information to guide follow-up care. Adjusting for race and comorbidities, survivors who wanted more information to guide their follow-up care reported greater worries about the future (p<0.05) and fears about disease recurrence (p<0.05) compared to those who did not want additional information. Conclusions Results emphasize the need to develop cancer survivorship educational strategies that are both responsive to the needs of specific populations (e.g., African American survivors and patients with multiple comorbidities) and the psychosocial profiles that motivate requests for more extensive follow-up guidance. PMID:25524391

Aesops Guide to Space Acquisition: Glimpses of Past and Future

DTIC Science & Technology

2015-04-01

Defense AT&L: March–April 2015 6 Aesop’s Guide to Space Acquisition Glimpses of Past and Future John Krieger n William “Lance” Krieger n Rick...U.S.C.) § 2273—Policy regarding assured access to space : national security payloads, establishes the requirement for the President to ensure our...access to space . (a) Policy—It is the policy of the United States for the President to undertake actions appropriate to ensure, to the maximum

Teacher's Guide to the Future.

ERIC Educational Resources Information Center

Murphy, Elaine M.; Cancellier, Patricia

1982-01-01

A brief introduction to futures education, an annotated listing of resources, and three ready-to-use student activities are provided. The introduction discusses the benefits of futures education; for example, it encourages students to make responsible decisions about the future. Next, it lists a variety of techniques developed by futurists to…

Illicit use of prescription stimulants in a college student sample: a theory-guided analysis.

PubMed

Bavarian, Niloofar; Flay, Brian R; Ketcham, Patricia L; Smit, Ellen

2013-10-01

The illicit use of prescription stimulants (IUPS) has emerged as a high-risk behavior of the 21st century college student. As the study of IUPS is relatively new, we aimed to understand (1) characteristics of IUPS (i.e., initiation, administration routes, drug sources, motives, experiences), and (2) theory-guided intrapersonal, interpersonal, and environmental correlates associated with use. Using one-stage cluster sampling, 520 students (96.3% response rate) at one Pacific Northwest University completed a paper-based, in-classroom survey on IUPS behaviors and expected correlates. Aim 1 was addressed using descriptive statistics and aim 2 was addressed via three nested logistic regression analyses guided by the Theory of Triadic Influence. The prevalence of ever engaging in IUPS during college was 25.6%. The majority (>50.0%) of users reported initiation during college, oral use, friends as the drug source, academic motives, and experiencing desired outcomes. Intrapersonal correlates associated with use included identifying as White, lower grade point average, diagnoses of attention deficit disorder, and lower avoidance self-efficacy. Interpersonal correlates of use included off-campus residence, varsity sports participation, IUPS perceptions by socializing agents, and greater behavioral norms. Exposure to prescription drug print media, greater prescription stimulant knowledge, and positive attitudes towards prescription stimulants were environmental correlates associated with use. In all models, IUPS intentions were strongly associated with use. IUPS was prevalent on the campus under investigation and factors from the intrapersonal, interpersonal and environmental domains were associated with the behavior. Implications for prevention and future research are discussed. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Illicit Use of Prescription Stimulants in a College Student Sample: A Theory-Guided Analysis*

PubMed Central

Bavarian, Niloofar; Flay, Brian R.; Ketcham, Patricia L.; Smit, Ellen

2013-01-01

Background The illicit use of prescription stimulants (IUPS) has emerged as a high-risk behavior of the 21st century college student. As the study of IUPS is relatively new, we aimed to understand 1) characteristics of IUPS (i.e., initiation, administration routes, drug sources, motives, experiences), and 2) theory-guided intrapersonal, interpersonal, and environmental correlates associated with use. Methods Using one-stage cluster sampling, 520 students (96.3% response rate) at one Pacific Northwest University completed a paper-based, in-classroom survey on IUPS behaviors and expected correlates. Aim 1 was addressed using descriptive statistics and aim 2 was addressed via three nested logistic regression analyses guided by the Theory of Triadic Influence. Results The prevalence of ever engaging in IUPS during college was 25.6%. The majority (>50.0%) of users reported initiation during college, oral use, friends as the drug source, academic motives, and experiencing desired outcomes. Intrapersonal correlates associated with use included identifying as White, lower grade point average, diagnoses of attention deficit disorder, and lower avoidance self-efficacy. Interpersonal correlates of use included off-campus residence, varsity sports participation, IUPS perceptions by socializing agents, and greater behavioral norms. Exposure to prescription drug print media, greater prescription stimulant knowledge, and positive attitudes towards prescription stimulants were environmental correlates associated with use. In all models, IUPS intentions were strongly associated with use. Conclusions IUPS was prevalent on the campus under investigation and factors from the intrapersonal, interpersonal and environmental domains were associated with the behavior. Implications for prevention and future research are discussed. PMID:23683794

Paradoxes in Film Ratings

ERIC Educational Resources Information Center

Moore, Thomas L.

2006-01-01

The author selected a simple random sample of 100 movies from the "Movie and Video Guide" (1996), by Leonard Maltin. The author's intent was to obtain some basic information on the population of roughly 19,000 movies through a small sample. The "Movie and Video Guide" by Leonard Maltin is an annual ratings guide to movies. While not all films ever…

Understanding and treatment of chronic abdominal pain in pediatric primary care.

PubMed

Schurman, Jennifer Verrill; Kessler, Emily D; Friesen, Craig A

2014-10-01

This study examined the practices used by primary care pediatricians to assess and treat chronic abdominal pain (CAP), as an initial step in guiding clinical practice guideline (CPG) development. A survey was mailed to a random sample of office-based pediatrician members (primary care pediatricians [PCPs]) of the American Medical Association. PCPs (n = 470) provided information about the typical presentation of CAP, assessment/treatment approaches used in their own practice, their definition of a functional gastrointestinal disorder (FGID), and their familiarity with the Rome Criteria for diagnosing FGIDs. Substantial variability among PCPs was noted across all these areas. Results suggest that perceptions and practices of pediatric CAP vary widely among PCPs; no single standard of care emerged to guide development of a CPG for this population. Future research should evaluate the efficacy of specific strategies currently in use to identify potential opportunities for improving assessment and treatment of CAP in pediatric primary care. © The Author(s) 2014.

Cerebral microbleeds: a guide to detection and interpretation.

PubMed

Greenberg, Steven M; Vernooij, Meike W; Cordonnier, Charlotte; Viswanathan, Anand; Al-Shahi Salman, Rustam; Warach, Steven; Launer, Lenore J; Van Buchem, Mark A; Breteler, Monique Mb

2009-02-01

Cerebral microbleeds (CMBs) are increasingly recognised neuroimaging findings in individuals with cerebrovascular disease and dementia, and in normal ageing. There has been substantial progress in the understanding of CMBs in recent years, particularly in the development of newer MRI methods for the detection of CMBs and the application of these techniques to population-based samples of elderly people. In this Review, we focus on these recent developments and their effects on two main questions: how CMBs are detected, and how CMBs should be interpreted. The number of CMBs detected depends on MRI characteristics, such as pulse sequence, sequence parameters, spatial resolution, magnetic field strength, and image post-processing, emphasising the importance of taking into account MRI technique in the interpretation of study results. Recent investigations with sensitive MRI techniques have indicated a high prevalence of CMBs in community-dwelling elderly people. We propose a procedural guide for identification of CMBs and suggest possible future approaches for elucidating the role of these common lesions as markers for, and contributors to, small-vessel brain disease.

Shade guide optimization--a novel shade arrangement principle for both ceramic and composite shade guides when identifying composite test objects.

PubMed

Østervemb, Niels; Jørgensen, Jette Nedergaard; Hørsted-Bindslev, Preben

2011-02-01

The most widely used shade guide for composite materials is made of ceramic and arranged according to a non-proven method. There is a need for a composite shade guide using a scientifically based arrangement principle. To compare the shade tab arrangement of the Vitapan Classical shade guide and an individually made composite shade guide using both the originally proposed arrangement principle and arranged according to ΔE2000 values with hue group division. An individual composite shade guide made from Filtek Supreme XT body colors was compared to the Vitapan Classical shade guide. Twenty-five students matched color samples made from Filtek Supreme XT body colors using the two shade guides arranged after the two proposed principles--four shade guides in total. Age, sequence, gender, time, and number of correct matches were recorded. The proposed visually optimal composite shade guide was both fastest and had the highest number of correct matches. Gender was significantly associated with time used for color sampling but not regarding the number of correct shade matches. A composite shade guide is superior compared to the ceramic Vitapan Classical guide when using composite test objects. A rearrangement of the shade guide according to hue, subdivided according to ΔE2000, significantly reduces the time needed to take a color sample and increases the number of correct shade matches. Total color difference in relation to the lightest tab with hue group division is recommended as a possible and universally applicable mode of tab arrangement in dental color standards. Moreover, a shade guide made of the composite materials itself is to be preferred as both a faster and more accurate method of determining color. © 2011, COPYRIGHT THE AUTHORS. JOURNAL COMPILATION © 2011, WILEY PERIODICALS, INC.

An Estimation of the Gamma-Ray Burst Afterglow Apparent Optical Brightness Distribution Function

NASA Astrophysics Data System (ADS)

Akerlof, Carl W.; Swan, Heather F.

2007-12-01

By using recent publicly available observational data obtained in conjunction with the NASA Swift gamma-ray burst (GRB) mission and a novel data analysis technique, we have been able to make some rough estimates of the GRB afterglow apparent optical brightness distribution function. The results suggest that 71% of all burst afterglows have optical magnitudes with mR<22.1 at 1000 s after the burst onset, the dimmest detected object in the data sample. There is a strong indication that the apparent optical magnitude distribution function peaks at mR~19.5. Such estimates may prove useful in guiding future plans to improve GRB counterpart observation programs. The employed numerical techniques might find application in a variety of other data analysis problems in which the intrinsic distributions must be inferred from a heterogeneous sample.

Asymmetrical booster ascent guidance and control system design study. Volume 4: Sampled data stability analysis program (SADSAP) user's guide. [space shuttle development

NASA Technical Reports Server (NTRS)

Wilson, J. L.

1974-01-01

A users guide to the Sampled Data Stability Analysis Program (SADSAP) is provided. This program is a general purpose sampled data Stability Analysis Program capable of providing frequency response on root locus data.

AFRICAN-AMERICANS’ AND LATINOS’ PERCEPTIONS OF USING HYPNOSIS TO ALLEVIATE DISTRESS BEFORE A COLONOSCOPY

PubMed Central

Miller, Sarah J.; Schnur, Julie B.; Montgomery, Guy H.; Jandorf, Lina

2013-01-01

Although colorectal cancer (CRC) screenings can effectively detect and prevent cancer, a large portion of African-Americans and Latinos do not undergo regular colonoscopy screening. Research suggests that anticipatory distress can significantly hinder minorities’ adherence to colonoscopy recommendations. There is significant promise that hypnosis may effectively reduce such distress. The current study examined African-Americans’ and Latinos’ (n = 213) perceptions of using hypnosis prior to a colonoscopy. Overall, 69.9% of the sample expressed favourable perceptions of using pre-colonoscopy hypnosis, although there was notable variability. The results from this study can guide clinical decision making and inform future research efforts. PMID:26566440

Space Flight. Teacher Resources.

ERIC Educational Resources Information Center

2001

This teacher's guide contains information, lesson plans, and diverse student learning activities focusing on space flight. The guide is divided into seven sections: (1) "Drawing Activities" (Future Flight; Space Fun; Mission: Draw); (2) "Geography" (Space Places); (3) "History" (Space and Time); (4)…

2013 Vehicle Theft Prevention Quick Reference Guide for the Law Enforcement Community

DOT National Transportation Integrated Search

2013-08-01

"This and future versions of the Vehicle TheftPrevention Quick Reference Guide for the Law Enforcement Community will provide comprehensive information for vehicle lines. The parts-marking requirements have been : extended to include: : all passe...

Soil Carbon Variability and Change Detection in the Forest Inventory Analysis Database of the United States

NASA Astrophysics Data System (ADS)

Wu, A. M.; Nater, E. A.; Dalzell, B. J.; Perry, C. H.

2014-12-01

The USDA Forest Service's Forest Inventory Analysis (FIA) program is a national effort assessing current forest resources to ensure sustainable management practices, to assist planning activities, and to report critical status and trends. For example, estimates of carbon stocks and stock change in FIA are reported as the official United States submission to the United Nations Framework Convention on Climate Change. While the main effort in FIA has been focused on aboveground biomass, soil is a critical component of this system. FIA sampled forest soils in the early 2000s and has remeasurement now underway. However, soil sampling is repeated on a 10-year interval (or longer), and it is uncertain what magnitude of changes in soil organic carbon (SOC) may be detectable with the current sampling protocol. We aim to identify the sensitivity and variability of SOC in the FIA database, and to determine the amount of SOC change that can be detected with the current sampling scheme. For this analysis, we attempt to answer the following questions: 1) What is the sensitivity (power) of SOC data in the current FIA database? 2) How does the minimum detectable change in forest SOC respond to changes in sampling intervals and/or sample point density? Soil samples in the FIA database represent 0-10 cm and 10-20 cm depth increments with a 10-year sampling interval. We are investigating the variability of SOC and its change over time for composite soil data in each FIA region (Pacific Northwest, Interior West, Northern, and Southern). To guide future sampling efforts, we are employing statistical power analysis to examine the minimum detectable change in SOC storage. We are also investigating the sensitivity of SOC storage changes under various scenarios of sample size and/or sample frequency. This research will inform the design of future FIA soil sampling schemes and improve the information available to international policy makers, university and industry partners, and the public.

User`s and reference guide to the INEL RML/analytical radiochemistry sample tracking database version 1.00

DOE Office of Scientific and Technical Information (OSTI.GOV)

Femec, D.A.

This report discusses the sample tracking database in use at the Idaho National Engineering Laboratory (INEL) by the Radiation Measurements Laboratory (RML) and Analytical Radiochemistry. The database was designed in-house to meet the specific needs of the RML and Analytical Radiochemistry. The report consists of two parts, a user`s guide and a reference guide. The user`s guide presents some of the fundamentals needed by anyone who will be using the database via its user interface. The reference guide describes the design of both the database and the user interface. Briefly mentioned in the reference guide are the code-generating tools, CREATE-SCHEMAmore » and BUILD-SCREEN, written to automatically generate code for the database and its user interface. The appendices contain the input files used by the these tools to create code for the sample tracking database. The output files generated by these tools are also included in the appendices.« less

Future Studies in the K-12 Curriculum.

ERIC Educational Resources Information Center

Haas, John D.

This guide is designed to help elementary and secondary school teachers and curriculum developers plan units on the future. It is presented in five sections. Section I discusses the origins of the modern futures movement and the concepts of future studies, time dimensions, global approach, self-fulfilling and self-defeating forecasts, and types of…

Resource Letter AFHEP-1: Accelerators for the Future of High-Energy Physics

NASA Astrophysics Data System (ADS)

Barletta, William A.

2012-02-01

This Resource Letter provides a guide to literature concerning the development of accelerators for the future of high-energy physics. Research articles, books, and Internet resources are cited for the following topics: motivation for future accelerators, present accelerators for high-energy physics, possible future machine, and laboratory and collaboration websites.

Integrated Sampling Strategy (ISS) Guide

Treesearch

Robert E. Keane; Duncan C. Lutes

2006-01-01

What is an Integrated Sampling Strategy? Simply put, it is the strategy that guides how plots are put on the landscape. FIREMON’s Integrated Sampling Strategy assists fire managers as they design their fire monitoring project by answering questions such as: What statistical approach is appropriate for my sample design? How many plots can I afford? How many plots do I...

Pocket guide to transportation, 1999

DOT National Transportation Integrated Search

1998-12-01

Statistics published in this Pocket Guide to Transportation come from many different sources. Some statistics are based on samples and are subject to sampling variability. Statistics may also be subject to omissions and errors in reporting, recording...

Pocket guide to transportation, 2009

DOT National Transportation Integrated Search

2009-01-01

Statistics published in this Pocket Guide to Transportation come from many different sources. Some statistics are based on samples and are subject to sampling variability. Statistics may also be subject to omissions and errors in reporting, recording...

Pocket guide to transportation, 2013.

DOT National Transportation Integrated Search

2013-01-01

Abstract Statistics published in this Pocket Guide to Transportation come from many different sources. Some statistics are based on samples and are subject to sampling variability. Statistics may also be subject to omissions and errors in reporting, ...

Pocket guide to transportation, 2010

DOT National Transportation Integrated Search

2010-01-01

Statistics published in this Pocket Guide to Transportation come from many different sources. Some statistics are based on samples and are subject to sampling variability. Statistics may also be subject to omissions and errors in reporting, recording...

Future Scenarios in Communications. Teacher's Guide. Preparing for Tomorrow's World.

ERIC Educational Resources Information Center

Iozzi, Louis A.; And Others

"Future Scenarios in Communications" is one of the "Preparing for Tomorrow's World" (PTW) program modules. PTW is an interdisciplinary, future-oriented program incorporating information from the sciences and social sciences and addressing societal concerns which interface science/technology/society. The program promotes…

Imaging the Ways to a Preferred Future.

ERIC Educational Resources Information Center

MacKenzie, Terri; Frommelt, Nancy

1985-01-01

Presents a series of exercises that can be used with any age level to stimulate visioning skills (e.g., dreaming, creating, intuiting, and imaging). The exercises focus on building imagination skills, guided imaging, envisioning the future that students would prefer, and creating a futures wheel. (DMM)

ISDP salt batch #2 supernate qualification

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peters, T. B.; Nash, C. A.; Fink, S. D.

2009-01-05

This report covers the laboratory testing and analyses of the second Integrated Salt Disposition Project (ISDP) salt supernate samples, performed in support of initial radioactive operations of Actinide Removal Process (ARP) and Modular Caustic-Side Solvent Extraction Unit (MCU). Major goals of this work include characterizing Tank 22H supernate, characterizing Tank 41H supernate, verifying actinide and strontium adsorption with a standard laboratory-scale test using monosodium titanate (MST) and filtration, and checking cesium mass transfer behavior for the MCU solvent performance when contacted with the liquid produced from MST contact. This study also includes characterization of a post-blend Tank 49H sample asmore » part of the Nuclear Criticality Safety Evaluation (NCSE). This work was specified by Task Technical Request and by Task Technical and Quality Assurance Plan (TTQAP). In addition, a sampling plan will be written to guide analytical future work. Safety and environmental aspects of the work were documented in a Hazard Assessment Package.« less

Propagating modes in gain-guided optical fibers.

PubMed

Siegman, A E

2003-08-01

Optical fibers in which gain-guiding effects are significant or even dominant compared with conventional index guiding may become of practical interest for future high-power single-mode fiber lasers. I derive the propagation characteristics of symmetrical slab waveguides and cylindrical optical fibers having arbitrary amounts of mixed gain and index guiding, assuming a single uniform transverse profile for both the gain and the refractive-index steps. Optical fibers of this type are best characterized by using a complex-valued v-squared parameter in place of the real-valued v parameter commonly used to describe conventional index-guided optical fibers.

Patient Activated Care for Rural Elderly. A Program Development and Teaching Guide for Planners, Facilitators, and Coordinators.

ERIC Educational Resources Information Center

Gaarder, Lorin R.; Cohen, Saul

This guide is an outline for developing and presenting programs in self health care for senior citizens. The guide is presented in two sections. The first section provides background information about elderly self-care and tips on teaching it and developing a program. Sample letters to prospective enrollees and sample news releases are included.…

Competency Based Instructional Resource Guide. Sample Format. Welding.

ERIC Educational Resources Information Center

Hoerner, James L.; Horne, Ralph A.

The purpose of this sample guide is to assist teachers and curriculum specialists in developing instructional materials that are competency based and that meet Virginia standards for competency-based education (CBE) programs. The sample deals with the occupation of welding, but it is the format that is of interest here, not the subject matter.…

Projects procedure guide : sampling frequencies for materials testing and inspection

DOT National Transportation Integrated Search

2002-02-01

The Bureau of Materials and Physical Research's Project Procedures Guide (PPG) is used as a resource for determining reasonable inspection procedures and sampling frequencies for materials used in highway construction. This Manual seeks to establish ...

In Situ Biological Contamination Studies of the Moon: Implications for Planetary Protection and Life Detection Missions

NASA Technical Reports Server (NTRS)

Glavin, Daniel P.; Dworkin, Jason P.; Lupisella, Mark; Williams, David R.; Kminek, Gerhard; Rummel, John D.

2010-01-01

NASA and ESA have outlined visions for solar system exploration that will include a series of lunar robotic precursor missions to prepare for, and support a human return to the Moan, and future human exploration of Mars and other destinations, including possibly asteroids. One of the guiding principles for exploration is to pursue compelling scientific questions about the origin and evolution of life. The search for life on objects such as Mars will require careful operations, and that all systems be sufficiently cleaned and sterilized prior to launch to ensure that the scientific integrity of extraterrestrial samples is not jeopardized by terrestrial organic contamination. Under the Committee on Space Research's (COSPAR's) current planetary protection policy for the Moon, no sterilization procedures are required for outbound lunar spacecraft, nor is there a different planetary protection category for human missions, although preliminary C SPAR policy guidelines for human missions to Mars have been developed. Future in situ investigations of a variety of locations on the Moon by highly sensitive instruments designed to search for biologically derived organic compounds would help assess the contamination of the Moon by lunar spacecraft. These studies could also provide valuable "ground truth" data for Mars sample return missions and help define planetary protection requirements for future Mars bound spacecraft carrying life detection experiments. In addition, studies of the impact of terrestrial contamination of the lunar surface by the Apollo astronauts could provide valuable data to help refine future: Mars surface exploration plans for a human mission to Mars.

Consistency in color parameters of a commonly used shade guide.

PubMed

Tashkandi, Esam

2010-01-01

The use of shade guides to assess the color of natural teeth subjectively remains one of the most common means for dental shade assessment. Any variation in the color parameters of the different shade guides may lead to significant clinical implications. Particularly, since the communication between the clinic and the dental laboratory is based on using the shade guide designation. The purpose of this study was to investigate the consistency of the L∗a∗b∗ color parameters of a sample of a commonly used shade guide. The color parameters of a total of 100 VITAPAN Classical Vacuum shade guide (VITA Zahnfabrik, Bad Säckingen, Germany(were measured using a X-Rite ColorEye 7000A Spectrophotometer (Grand Rapids, Michigan, USA). Each shade guide consists of 16 tabs with different designations. Each shade tab was measured five times and the average values were calculated. The ΔE between the average L∗a∗b∗ value for each shade tab and the average of the 100 shade tabs of the same designation was calculated. Using the Student t-test analysis, no significant differences were found among the measured sample. There is a high consistency level in terms of color parameters of the measured VITAPAN Classical Vacuum shade guide sample tested.

Laboratory study of concrete properties to support implementation of the new AASHTO mechanistic-empirical pavement design guide.

DOT National Transportation Integrated Search

2012-09-01

Properties of concrete embodying materials typically used in Wisconsin paving projects were evaluated in support of future : implementation of the AASHTO Mechanistic-Empirical Pavement Design Guide (MEPDG). The primary concrete : properties studied w...

Laboratory study of concrete properties to support implementation of the new AASHTO mechanistic empirical pavement design guide.

DOT National Transportation Integrated Search

2012-09-01

Properties of concrete embodying materials typically used in Wisconsin paving projects were evaluated in support of future : implementation of the AASHTO Mechanistic-Empirical Pavement Design Guide (MEPDG). The primary concrete : properties studied w...

V-TECS Guide for Automobile Engine Performance Technician.

ERIC Educational Resources Information Center

Meyer, Calvin F.; Benson, Robert T.

This guide is intended to assist teachers responsible for instructing future auto engine performance technicians. The following topics are covered: diagnosing engine performance problems, ignition system problems, fuel system problems, mechanically related performance problems, emission control system problems, and electronic control systems;…

Strategic plan : our guide to the future

DOT National Transportation Integrated Search

1997-01-01

The Federal Aviation Administration Logistics Center's strategic plan provides a direction for the future based on analysis of factors affecting current Logistics Center business operations. The FAA Logistics Center management team analyzed the curre...

Photonic-crystal fiber as a multifunctional optical sensor and sample collector.

PubMed

Konorov, Stanislav; Zheltikov, Aleksei; Scalora, Michael

2005-05-02

Two protocols of optical sensing realized with the same photonic-crystal fiber are compared. In the first protocol, diode-laser radiation is delivered to a sample through the central core of a dual-cladding photonic-crystal fiber with a diameter of a few micrometers, while the large-diameter fiber cladding serves to collect the fluorescent response from the sample and to guide it to a detector in the backward direction. In the second scheme, liquid sample is collected by a microcapillary array in the fiber cladding and is interrogated by laser radiation guided in the fiber modes. For sample fluids with refractive indices exceeding the refractive index of the fiber material, fluid channels in photonic-crystal fibers can guide laser light by total internal reflection, providing an 80% overlap of interrogating radiation with sample fluid.

Creating Futures Activity Cards and Teacher Guide.

ERIC Educational Resources Information Center

Klenzman, Elizabeth; Taylor, Paula

Teachers can use these learning activities to teach about the future in elementary and secondary social studies, science, math, language arts, and arts courses. The purpose of the activities is to help students practice creative-thinking skills, investigate problems relevant to their personal futures, experience the concept of change, and evaluate…

Jobs for Indiana's Future. Executive Report.

ERIC Educational Resources Information Center

Jobs for the Future, Inc., West Somerville, MA.

This report summarizes the work of the Jobs for Indiana's Future (JIF) program, designed to provide the Indiana Commission on Vocational and Technical Education (ICVTE) with assistance in planning for the future by enhancing ICVTE's capacity to guide Indiana's human capital investment strategy. The JIF program undertook an extensive analysis of…

Making It Happen: A Positive Guide to the Future.

ERIC Educational Resources Information Center

Richardson, John M., Jr., Ed.

This compilation of articles, photographs, commentaries, diagrams, and political cartoons presents positive, practical, and action-oriented core ideas on which to base future-oriented thinking and creative activity. The first of 10 parts presents articles on traditional American principles, ways of facing the future, America's character and…

Visions to Guide Performance: A Typology of Multiple Future Organizational Images

ERIC Educational Resources Information Center

Margolis, Sheila L.; Hansen, Carol D.

2003-01-01

Organizational performance is highly influenced by how employees envision the future. To date, many scholars have emphasized the importance of an overarching future vision that unites all stakeholders, while acknowledging the presence of divergent perspectives among members. This variety in perspectives may be further complicated in organizations…

Testing the Feasibility of Developmental Asset Measures on College Students to Guide Health Promotion Efforts

ERIC Educational Resources Information Center

Zullig, Keith J.; Ward, Rose Marie; King, Keith A.; Patton, Jon M.; Murray, Karen A.

2009-01-01

The purpose of this investigation was to assess the reliability and validity of eight developmental asset measures among a stratified, random sample (N = 540) of college students to guide health promotion efforts. The sample was randomly split to produce exploratory and confirmatory samples for factor analysis using principal axis factoring and…

Retirement Preparation Guide.

ERIC Educational Resources Information Center

Maddron, Edith, Ed.

This guide consists of ten articles, each introducing a separate issue important to retirement planning. The series discusses a wide range of information about critical retirement issues and explores the uncertainties, expectations, and decisions that confront the future retiree. The articles also contain suggestions and planning aids, worksheets,…

Towards a Reduced-Wire Interface for CMUT-Based Intravascular Ultrasound Imaging Systems

PubMed Central

Lim, Jaemyung; Tekes, Coskun; Degertekin, F. Levent; Ghovanloo, Maysam

2016-01-01

Having intravascular ultrasound (IVUS) imaging capability on guide wires used in cardiovascular interventions may eliminate the need for separate IVUS catheters and expand the use of IVUS in a larger portion of the vasculature. High frequency capacitive micro machined ultrasonic transducer (CMUT) arrays should be integrated with interface electronics and placed on the guide wire for this purpose. Besides small size, this system-on-a-chip (SoC) front-end should connect to the back-end imaging system with a minimum number of wires to preserve the critical mechanical properties of the guide wire. We present a 40 MHz CMUT array interface SoC, which will eventually use only two wires for power delivery and transmits image data using a combination of analog-to-time conversion (ATC) and an impulse radio ultra-wideband (IR-UWB) wireless link. The proof-of-concept prototype ASIC consumes only 52.8 mW and occupies 4.07 mm2 in a 0.35-μm standard CMOS process. A rectifier and regulator power the rest of the SoC at 3.3 V from a 10 MHz power carrier that is supplied through a 2.4 m micro-coax cable with an overall efficiency of 49.1%. Echo signals from an 8-element CMUT array are amplified by a transimpedance amplifier (TIA) array and down-converted to baseband by quadrature sampling using a 40 MHz clock, derived from the power carrier. The ATC generates pulse-width-modulated (PWM) samples at 2 × 10 MS/s with 6 bit resolution, while the entire system achieved 5.1 ENOB. Preliminary images from the prototype system are presented, and alternative data transmission and possible future directions towards practical implementation are discussed. PMID:27662686

Towards a Reduced-Wire Interface for CMUT-Based Intravascular Ultrasound Imaging Systems.

PubMed

Lim, Jaemyung; Tekes, Coskun; Degertekin, F Levent; Ghovanloo, Maysam

2017-04-01

Having intravascular ultrasound (IVUS) imaging capability on guide wires used in cardiovascular interventions may eliminate the need for separate IVUS catheters and expand the use of IVUS in a larger portion of the vasculature. High frequency capacitive micro machined ultrasonic transducer (CMUT) arrays should be integrated with interface electronics and placed on the guide wire for this purpose. Besides small size, this system-on-a-chip (SoC) front-end should connect to the back-end imaging system with a minimum number of wires to preserve the critical mechanical properties of the guide wire. We present a 40 MHz CMUT array interface SoC, which will eventually use only two wires for power delivery and transmits image data using a combination of analog-to-time conversion (ATC) and an impulse radio ultra-wideband (IR-UWB) wireless link. The proof-of-concept prototype ASIC consumes only 52.8 mW and occupies 4.07 [Formula: see text] in a 0.35- [Formula: see text] standard CMOS process. A rectifier and regulator power the rest of the SoC at 3.3 V from a 10 MHz power carrier that is supplied through a 2.4 m micro-coax cable with an overall efficiency of 49.1%. Echo signals from an 8-element CMUT array are amplified by a transimpedance amplifier (TIA) array and down-converted to baseband by quadrature sampling using a 40 MHz clock, derived from the power carrier. The ATC generates pulse-width-modulated (PWM) samples at 2 × 10 MS/s with 6 bit resolution, while the entire system achieved 5.1 ENOB. Preliminary images from the prototype system are presented, and alternative data transmission and possible future directions towards practical implementation are discussed.

Global biogeographic sampling of bacterial secondary metabolism

PubMed Central

Charlop-Powers, Zachary; Owen, Jeremy G; Reddy, Boojala Vijay B; Ternei, Melinda A; Guimarães, Denise O; de Frias, Ulysses A; Pupo, Monica T; Seepe, Prudy; Feng, Zhiyang; Brady, Sean F

2015-01-01

Recent bacterial (meta)genome sequencing efforts suggest the existence of an enormous untapped reservoir of natural-product-encoding biosynthetic gene clusters in the environment. Here we use the pyro-sequencing of PCR amplicons derived from both nonribosomal peptide adenylation domains and polyketide ketosynthase domains to compare biosynthetic diversity in soil microbiomes from around the globe. We see large differences in domain populations from all except the most proximal and biome-similar samples, suggesting that most microbiomes will encode largely distinct collections of bacterial secondary metabolites. Our data indicate a correlation between two factors, geographic distance and biome-type, and the biosynthetic diversity found in soil environments. By assigning reads to known gene clusters we identify hotspots of biomedically relevant biosynthetic diversity. These observations not only provide new insights into the natural world, they also provide a road map for guiding future natural products discovery efforts. DOI: http://dx.doi.org/10.7554/eLife.05048.001 PMID:25599565

Waterborne norovirus outbreak in a municipal drinking-water supply in Sweden.

PubMed

Riera-Montes, M; Brus Sjölander, K; Allestam, G; Hallin, E; Hedlund, K-O; Löfdahl, M

2011-12-01

During Easter 2009, almost 200 people resident in a small Swedish village fell ill with gastrointestinal symptoms. We conducted a retrospective cohort study and a molecular investigation in order to identify the source of the outbreak. Residents living in households connected to the public water network were at an increased risk of developing disease (relative risk 4·80, 95% confidence interval 1·68-13·73) compared to those with no connection to the public network. Norovirus genotype GI.3 was identified in stool samples from six patients and in a sample from the public water network. Contamination of one of the wells supplying the public water network was thought to be the source of the outbreak. This is a description of a norovirus outbreak linked to a municipal drinking-water supply in Sweden. Information from epidemiological and molecular investigations is of utmost importance to guide outbreak control measures and to prevent future outbreaks.

Optimal health and disease management using spatial uncertainty: a geographic characterization of emergent artemisinin-resistant Plasmodium falciparum distributions in Southeast Asia.

PubMed

Grist, Eric P M; Flegg, Jennifer A; Humphreys, Georgina; Mas, Ignacio Suay; Anderson, Tim J C; Ashley, Elizabeth A; Day, Nicholas P J; Dhorda, Mehul; Dondorp, Arjen M; Faiz, M Abul; Gething, Peter W; Hien, Tran T; Hlaing, Tin M; Imwong, Mallika; Kindermans, Jean-Marie; Maude, Richard J; Mayxay, Mayfong; McDew-White, Marina; Menard, Didier; Nair, Shalini; Nosten, Francois; Newton, Paul N; Price, Ric N; Pukrittayakamee, Sasithon; Takala-Harrison, Shannon; Smithuis, Frank; Nguyen, Nhien T; Tun, Kyaw M; White, Nicholas J; Witkowski, Benoit; Woodrow, Charles J; Fairhurst, Rick M; Sibley, Carol Hopkins; Guerin, Philippe J

2016-10-24

Artemisinin-resistant Plasmodium falciparum malaria parasites are now present across much of mainland Southeast Asia, where ongoing surveys are measuring and mapping their spatial distribution. These efforts require substantial resources. Here we propose a generic 'smart surveillance' methodology to identify optimal candidate sites for future sampling and thus map the distribution of artemisinin resistance most efficiently. The approach uses the 'uncertainty' map generated iteratively by a geostatistical model to determine optimal locations for subsequent sampling. The methodology is illustrated using recent data on the prevalence of the K13-propeller polymorphism (a genetic marker of artemisinin resistance) in the Greater Mekong Subregion. This methodology, which has broader application to geostatistical mapping in general, could improve the quality and efficiency of drug resistance mapping and thereby guide practical operations to eliminate malaria in affected areas.

Health promotion in pediatric primary care: importance of health literacy and communication practices.

PubMed

Davis, Deborah Winders; Jones, V Faye; Logsdon, M Cynthia; Ryan, Lesa; Wilkerson-McMahon, Mandie

2013-12-01

Health literacy has been shown to predict health behaviors and outcomes above the effects of education or socioeconomic status. Much remains unknown about the health literacy of parents and the role it plays in children's health outcomes or in health disparities. The current study explored the health communication needs and health literacy indicators in a diverse sample of parents (n = 75) to identify potential areas for future interventions. The sample consisted of parents of children 18 to 36 months old who were visiting 3 different pediatric medical offices, 2 of which served low-income families and 1 located in an affluent suburb. When comparisons were made between 2 educational attainment groups, there were variations in indicators of health literacy and health communication needs. These data can be used to guide the development of interventions by primary care providers to improve parent education.

Indiana rail plan

DOT National Transportation Integrated Search

2009-07-08

The 2009 Indiana Rail Plan was developed as part of the Indiana Multimodal Freight and Mobility Plan to direct the State of Indianas future freight and passenger rail policy, provide a framework to guide future decisions regarding rail system inve...

Ten principles for thinking about the future: a primer for environmental professionals

Treesearch

David N. Bengston

2017-01-01

Every decision we make is about the future, but most of us are never taught how to think critically about it. This guide addresses this issue by identifying and reviewing 10 principles for thinking about the future, along with related strategies for improving environmental foresight. The principles and strategies are drawn from the transdisciplinary field of futures...

Ultrasound-guided percutaneous fine-needle aspiration of 545 focal pancreatic lesions.

PubMed

Zamboni, Giulia A; D'Onofrio, Mirko; Idili, Antonio; Malagò, Roberto; Iozzia, Roberta; Manfrin, Erminia; Mucelli, Roberto Pozzi

2009-12-01

The purpose of this study was to assess the accuracy and short-term complication rate of ultrasound-guided fine-needle aspiration cytologic sampling of focal pancreatic lesions. We reviewed 545 consecutive ultrasound-guided fine-needle aspiration cytologic sampling procedures for focal pancreatic lesions from January 2004 through June 2008. The procedures were performed with a 20- or 21-gauge needle. The onsite cytopathologist evaluated the appropriateness of the sample and made a diagnosis. We reviewed the final diagnosis and the radiologic and medical records of all patients for onset of complications during or within 7 days of the procedure. The study sample included 262 women and 283 men (mean age, 62 years; range, 25-86 years). The head or uncinate process of the pancreas was the location of 63.0% of the lesions, and 35.2% of the lesions were located in the body or tail of the pancreas. The site of 10 lesions (1.8%) was not specified. Sampling was diagnostic in 509 of the 545 cases (93.4%). Excluding the 36 nondiagnostic samples, ultrasound-guided fine-needle aspiration cytologic sampling had 99.4% sensitivity, 100% specificity, and 99.4% accuracy. In 537 of the 545 cases (98.5%), the procedure was uneventful. In two cases, abdominal fluid was found after the procedure that was not present before the procedure. Six patients experienced postprocedural pain without abnormal findings at subsequent imaging. No major complications occurred. Ultrasound-guided cytologic sampling is safe and accurate for the diagnosis and planning of management of focal pancreatic lesions. With a cytologist on site, the rate of acquisition of samples adequate for diagnosis is high, reducing the need for patient recall.

Sampling optimization for high-speed weigh-in-motion measurements using in-pavement strain-based sensors

NASA Astrophysics Data System (ADS)

Zhang, Zhiming; Huang, Ying; Bridgelall, Raj; Palek, Leonard; Strommen, Robert

2015-06-01

Weigh-in-motion (WIM) measurement has been widely used for weight enforcement, pavement design, freight management, and intelligent transportation systems to monitor traffic in real-time. However, to use such sensors effectively, vehicles must exit the traffic stream and slow down to match their current capabilities. Hence, agencies need devices with higher vehicle passing speed capabilities to enable continuous weight measurements at mainline speeds. The current practices for data acquisition at such high speeds are fragmented. Deployment configurations and settings depend mainly on the experiences of operation engineers. To assure adequate data, most practitioners use very high frequency measurements that result in redundant samples, thereby diminishing the potential for real-time processing. The larger data memory requirements from higher sample rates also increase storage and processing costs. The field lacks a sampling design or standard to guide appropriate data acquisition of high-speed WIM measurements. This study develops the appropriate sample rate requirements as a function of the vehicle speed. Simulations and field experiments validate the methods developed. The results will serve as guidelines for future high-speed WIM measurements using in-pavement strain-based sensors.

75 FR 45171 - Notice of Issuance of Regulatory Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-02

... Engineering, Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission, Washington, DC 20555...-3040. This guide describes some engineering practices and methods generally considered by the NRC to be... they reflect the latest general engineering approaches that are acceptable to the NRC staff. If future...

Guide to the measurement of tree characteristics important to the quality classification for young hardwood trees

Treesearch

David L. Sonderman

1979-01-01

A procedure is shown for measuring external tree characteristics that are important in determining the current and future quality of young hardwood trees. This guide supplements a precious study which describes the quality classification system for young hardwood trees

Electricity: Today's Technologies, Tomorrow's Alternatives. Teacher's Guide.

ERIC Educational Resources Information Center

Electric Power Research Inst., Palo Alto, CA.

This teaching guide is designed to help teachers develop lesson plans around nine chapters provided in the student textbook. Chapters focus on energy use, energy demand, energy supply, principles of electric power generation, today's generating options, future generating options, electricity storage and delivery, environmental concerns, and making…

Soils Sampling and Testing Training Guide for Field and Laboratory Technicians on Roadway Construction

DOT National Transportation Integrated Search

1999-12-01

This manual has been developed as a training guide for field and laboratory technicians responsible for sampling and testing of soils used in roadway construction. Soils training and certification will increase the knowledge of laboratory, production...

The universal, collaborative and dynamic model of specialist and advanced nursing and midwifery practice: A way forward?

PubMed

O'Connor, Laserina; Casey, Mary; Smith, Rita; Fealy, Gerard M; Brien, Denise O'; O'Leary, Denise; Stokes, Diarmuid; McNamara, Martin S; Glasgow, Mary Ellen; Cashin, Andrew

2018-03-01

To inform and guide the development of a future model of specialist and advanced nursing and midwifery practice. There is a sizable body of empirical literature supporting the unique contributions of specialist and advanced practice roles to health care. However, there is very little international evidence to inform the integration of a future model for advanced or specialist practice in the Irish healthcare system. A qualitative study was conducted to initiate this important area of inquiry. Purposive sampling was used to generate a sample of informants (n = 15) for the interviews. Nurses and midwives working in specialist and advanced practice and participants from other areas such as legislative, regulatory, policy, medicine and education were included in the sampling frame. Arguments for a new model of specialist and advanced practice were voiced. A number of participants proposed that flexibility within specialist and advanced practitioner career pathways was essential. Otherwise, there existed the possibility of being directed into specialised "silos," precluding movement to another area of integrated practice. Future specialist and advanced practice education programmes need to include topics such as the development of emotional and political intelligence. The contribution of specialist and advanced practice roles to the health service includes providing rapid access to care, seamless patient flow across services, early discharge and lead coordinator of the patient's care trajectory. There was a recommendation of moving towards a universal model to cultivate specialist and advanced nurse and midwife practitioners. The model design has Universal application in a range of contexts "U." It is Collaborative in its inclusivity of all key stakeholders "C." The model is Dynamic pertinent to accommodating movement of nurses and midwives across health continua rather than plateauing in very specialised "silos" "D." © 2017 John Wiley & Sons Ltd.

Findings from a strength-based moderate-intensity exercise interventions for individuals with dementia (innovative practice).

PubMed

Dawson, Nicole; Gerhart, Hayden; Judge, Katherine S

2017-01-01

Limited evidence exists regarding exercise interventions with individuals with dementia, which is often due to heterogeneity of methodology and outcomes being assessed. This led to the development and evaluation of a moderate-intensity home-based functional exercise program guided by theories from exercise science and the Strength-Based Approach. Data indicated excellent treatment adherence (99.04%) along with high levels of acceptability and feasibility in this sample (age 76.63 years (9.84); Mini Mental State Exam 18.87 (6.40)). This article informs future practice by highlighting the merits of a Strength-Based Approach in research examining exercise and physical rehabilitation to improve adherence and compliance with individuals with dementia.

Simulator for multilevel optimization research

NASA Technical Reports Server (NTRS)

Padula, S. L.; Young, K. C.

1986-01-01

A computer program designed to simulate and improve multilevel optimization techniques is described. By using simple analytic functions to represent complex engineering analyses, the simulator can generate and test a large variety of multilevel decomposition strategies in a relatively short time. This type of research is an essential step toward routine optimization of large aerospace systems. The paper discusses the types of optimization problems handled by the simulator and gives input and output listings and plots for a sample problem. It also describes multilevel implementation techniques which have value beyond the present computer program. Thus, this document serves as a user's manual for the simulator and as a guide for building future multilevel optimization applications.

Future Air Traffic Growth and Schedule Model User's Guide

NASA Technical Reports Server (NTRS)

Kimmel, William M. (Technical Monitor); Smith, Jeremy C.; Dollyhigh, Samuel M.

2004-01-01

The Future Air Traffic Growth and Schedule Model was developed as an implementation of the Fratar algorithm to project future traffic flow between airports in a system and of then scheduling the additional flights to reflect current passenger time-of-travel preferences. The methodology produces an unconstrained future schedule from a current (or baseline) schedule and the airport operations growth rates. As an example of the use of the model, future schedules are projected for 2010 and 2022 for all flights arriving at, departing from, or flying between all continental United States airports that had commercial scheduled service for May 17, 2002. Inter-continental US traffic and airports are included and the traffic is also grown with the Fratar methodology to account for their arrivals and departures to the continental US airports. Input data sets derived from the Official Airline Guide (OAG) data and FAA Terminal Area Forecast (TAF) are included in the examples of the computer code execution.

Protocol for a feasibility study of a self-help cognitive behavioural therapy resource for the reduction of dental anxiety in young people.

PubMed

Marshman, Zoe; Morgan, Annie; Porritt, Jenny; Gupta, Ekta; Baker, Sarah; Creswell, Cathy; Newton, Tim; Stevens, Katherine; Williams, Christopher; Prasad, Suneeta; Kirby, Jennifer; Rodd, Helen

2016-01-01

Childhood dental anxiety is very common, with 10-20 % of children and young people reporting high levels of dental anxiety. It is distressing and has a negative impact on the quality of life of young people and their parents as well as being associated with poor oral health. Affected individuals may develop a lifelong reliance on general anaesthetic or sedation for necessary dental treatment thus requiring the support of specialist dental services. Children and young people with dental anxiety therefore require additional clinical time and can be costly to treat in the long term. The reduction of dental anxiety through the use of effective psychological techniques is, therefore, of high importance. However, there is a lack of high-quality research investigating the impact of cognitive behavioural therapy (CBT) approaches when applied to young people's dental anxiety. The first part of the study will develop a profile of dentally anxious young people using a prospective questionnaire sent to a consecutive sample of 100 young people referred to the Paediatric Dentistry Department, Charles Clifford Dental Hospital, in Sheffield. The second part will involve interviewing a purposive sample of 15-20 dental team members on their perceptions of a CBT self-help resource for dental anxiety, their opinions on whether they might use such a resource with patients, and their willingness to recruit participants to a future randomised controlled trial (RCT) to evaluate the resource. The third part of the study will investigate the most appropriate outcome measures to include in a trial, the acceptability of the resource, and retention and completion rates of treatment with a sample of 60 dentally anxious young people using the CBT resource. This study will provide information on the profile of dentally anxious young people who could potentially be helped by a guided self-help CBT resource. It will gain the perceptions of dental care team members of guided self-help CBT for dental anxiety in young people and their willingness to recruit participants to a trial. Acceptability of the resource to participants and retention and completion rates will also be investigated to inform a future RCT.

Reinstated episodic context guides sampling-based decisions for reward.

PubMed

Bornstein, Aaron M; Norman, Kenneth A

2017-07-01

How does experience inform decisions? In episodic sampling, decisions are guided by a few episodic memories of past choices. This process can yield choice patterns similar to model-free reinforcement learning; however, samples can vary from trial to trial, causing decisions to vary. Here we show that context retrieved during episodic sampling can cause choice behavior to deviate sharply from the predictions of reinforcement learning. Specifically, we show that, when a given memory is sampled, choices (in the present) are influenced by the properties of other decisions made in the same context as the sampled event. This effect is mediated by fMRI measures of context retrieval on each trial, suggesting a mechanism whereby cues trigger retrieval of context, which then triggers retrieval of other decisions from that context. This result establishes a new avenue by which experience can guide choice and, as such, has broad implications for the study of decisions.

Kinematic analysis and simulation of a substation inspection robot guided by magnetic sensor

NASA Astrophysics Data System (ADS)

Xiao, Peng; Luan, Yiqing; Wang, Haipeng; Li, Li; Li, Jianxiang

2017-01-01

In order to improve the performance of the magnetic navigation system used by substation inspection robot, the kinematic characteristics is analyzed based on a simplified magnetic guiding system model, and then the simulation process is executed to verify the reasonability of the whole analysis procedure. Finally, some suggestions are extracted out, which will be helpful to guide the design of the inspection robot system in the future.

Mechanics. Secondary Schools. Curriculum Guide.

ERIC Educational Resources Information Center

Trust Territory of the Pacific Islands Dept. of Education, Saipan.

This document, a curriculum guide for auto mechanics for secondary students, is one of six guides developed for inservice teachers at Marianas High School in Saipan. The guide provides the rationale, description, goals, and objectives of the program; the program of studies and performance objectives by levels; samples of lesson plans for effective…

Potential impact of future climate change on sugarcane under dryland conditions in Mexico

USDA-ARS?s Scientific Manuscript database

Assessments of impacts of future climate change on widely grown sugarcane varieties can guide decision-making at various levels and help ensure the economic stability of numerous rural households. This study assessed the potential impact of future climatic change on CP 72-2086 the most widely grown...

Examination of print and telephone channels for physical activity promotion: Rationale, design, and baseline data from Project STRIDE.

PubMed

Marcus, Bess H; Napolitano, Melissa A; King, Abby C; Lewis, Beth A; Whiteley, Jessica A; Albrecht, Anna E; Parisi, Alfred F; Bock, Beth C; Pinto, Bernardine M; Sciamanna, Christopher A; Jakicic, John M; Papandonatos, George D

2007-01-01

Project STRIDE is a 4-year randomized controlled trial comparing two computer-based expert system guided intervention delivery channels (phone vs. print) for physical activity adoption and short-term maintenance among previously sedentary adults. Sedentary adults (n=239) were randomized to one of the following (1) telephone-based, individualized motivationally-tailored feedback; (2) print-based, individualized motivationally-tailored feedback; (3) contact-control delayed treatment group (received intervention after 12 months as control). This paper: (1) outlines the study design, rationale, and participant sample; and (2) describes relationships between baseline variables to better understand their influence on the efficacy of the intervention. Participants averaged 19.8+/-25.0 min of physical activity/week that was at least of moderate intensity, with no group differences. The average estimated VO(2) at 85% of maximum heart rate was 25.6 ml/kg/min. Body fat was 34.1% for women and 23.2% for men and the BMI of the sample averaged 28.5 kg/m(2). Project STRIDE examines non face-to-face approaches for promoting physical activity behavior. It has unique features including a direct comparison of an expert system guided intervention delivered via phone or print. Future analyses will examine the cost-effectiveness of the interventions and this will likely yield important information for policy-makers.

Brownfield to Brightfield Initiative in Oak Ridge, TN - 12346

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hough, Gil; Fairless, Chad

Experience characterizing, permitting, and restoring 'Brownfield' sites-government or industrial sites with restricted future use due to the presence or potential presence of hazardous substances, pollutants, or contaminants-is being leveraged to identify opportunities for redevelopment into solar power generating facilities which, in this context, are called 'Brightfields'. Brownfield sites offer the expansive land necessary for large photovoltaic (PV) solar farms, but require an in-depth working knowledge of complicated regulatory restrictions and environmental constraints to develop them. As a part of the effort to identify opportunities for redevelopment of Brownfield sites for solar applications, a technical guide, was composed specifically for themore » development of solar generation on restricted use sites. The basis of the technical guide gives specific consideration to environmental requirements and installation methods breaking that into three areas for assessing: 1) levels of contamination, 2) ground penetration requirements, and 3) the requirements for aesthetics and maintenance. Brightfield projects are underway to support the technical guide and expand re-industrialization efforts for the former DOE Gaseous Diffusion Plant in Oak Ridge, TN. There are exciting opportunities to turn Brownfields into Brightfield solar energy solutions for meeting the future renewable energy needs of our country. Brownfields that offer the large surface area required for solar PV farms coupled with the technical guide for the installation of solar farms on restricted use sites supports efforts to develop the solar capacities and expertise to tap this future market. The initial projects designed following the technical guide will provide verification of the installation requirements and beneficial reuse of restricted use sites. (authors)« less

National Audubon Society Specials. Teacher's Guide I.

ERIC Educational Resources Information Center

WETA - TV, Washington, DC.

Since no civilization can survive without a healthy environment, people must learn to live in harmony with their natural ecosystems and build for future generations. This guide describes six award-winning programs on the condor, black-footed ferret, panthers and cheetahs, ducks, farming and wildlife, and the Galapagos Islands. Although each…

A Guide to the Identification of Training Needs. Second Edition.

ERIC Educational Resources Information Center

Boydell, T. H.

This guide is intended to help planners and trainers assess the training needs of industrial organizations. Addressed in the individual chapters are the following topics: types of training needs (three levels of needs--organizational, occupational, individual, organizational training needs and objectives, and present and future needs); present…

Citizen Action. Teacher's Guide to World Resources. Comprehensive Coursework on the Global Environment.

ERIC Educational Resources Information Center

Snyder, Sarah A.

This teacher's guide presents teaching suggestions and presentation materials about citizen action in the global environment. Focusing on the nongovernmental organizations (NGOs), the lessons describe the roles NGOs play in positively influencing future trends in social development, natural resources management, and environmental quality. NGOs are…

Strategic Planning in Education: A Guide for Policymakers.

ERIC Educational Resources Information Center

Cooper, Harry A.

As defined in chapter I of this guide for policymakers, strategic planning is the method by which an organization identifies relevant trends in its environment, analyzes their potential implications, and projects an integrated strategy to address these future events and their contingencies. This process differs from formalized planning, based on…

Forecasting the Future: Exploring Evidence for Global Climate Change.

ERIC Educational Resources Information Center

California Univ., San Diego, La Jolla. Inst. of Marine Resources.

This curriculum and classroom activity guide considers evidence gathered in answer to questions concerning global environmental change. It describes methods that biologists, chemists, geologists, meteorologists, and physicists use to gather and interpret their findings. The activities and approaches in this guide were developed to meet the skill…

CNC Turning Technician. A Competency-Based Instructional System.

ERIC Educational Resources Information Center

Sloan, Kelly; Hilley, Robert

This competency-based curriculum guide for instructing students in using computer numerically controlled (CNC) turning machines is one of a series of instructional guides for the machinist field developed in Oklahoma. Although developed jointly with Baxter Technologies Corporation and oriented toward the Baxter Vo-Tec 2000 Future Builder CNC…

Secondary School Curriculum Guide: Industrial Arts.

ERIC Educational Resources Information Center

Cranston School Dept., RI.

The Cranston Secondary School Curriculum Guide (9-12) for Industrial Arts is intended to serve as a resource for teachers, students, department chairman, guidance personnel, curriculum planners, and others involved in present or future curriculum planning. At least one broadly stated major objective is provided for each section, encompassing the…

Scanning the Future: Preparing for Employment through Career Development.

ERIC Educational Resources Information Center

South Carolina State Dept. of Education, Columbia. Office of Occupational Education.

This curriculum guide, developed in South Carolina, provides opportunities for students to develop positive attitudes toward work, learn about occupations, and seek and retain employment. It is based on the competencies and foundations identified by the Secretary's Commission on Achieving Necessary Skills (SCANS). The guide's four units cover…

Secondary School Curriculum Guide: Business: Grades 9-12.

ERIC Educational Resources Information Center

Cranston School Dept., RI.

The Cranston Secondary School Curriculum Guide (9-12) for Business Education is intended to serve as a resource for teachers, students, department chairman, guidance personnel, curriculum planners, and others involved in present or future curriculum planning. At least one broadly stated major objective is provided for each section, encompassing…

Prototype of a laser guide star wavefront sensor for the Extremely Large Telescope

NASA Astrophysics Data System (ADS)

Patti, M.; Lombini, M.; Schreiber, L.; Bregoli, G.; Arcidiacono, C.; Cosentino, G.; Diolaiti, E.; Foppiani, I.

2018-06-01

The new class of large telescopes, like the future Extremely Large Telescope (ELT), are designed to work with a laser guide star (LGS) tuned to a resonance of atmospheric sodium atoms. This wavefront sensing technique presents complex issues when applied to big telescopes for many reasons, mainly linked to the finite distance of the LGS, the launching angle, tip-tilt indetermination and focus anisoplanatism. The implementation of a laboratory prototype for the LGS wavefront sensor (WFS) at the beginning of the phase study of MAORY (Multi-conjugate Adaptive Optics Relay) for ELT first light has been indispensable in investigating specific mitigation strategies for the LGS WFS issues. This paper presents the test results of the LGS WFS prototype under different working conditions. The accuracy within which the LGS images are generated on the Shack-Hartmann WFS has been cross-checked with the MAORY simulation code. The experiments show the effect of noise on centroiding precision, the impact of LGS image truncation on wavefront sensing accuracy as well as the temporal evolution of the sodium density profile and LGS image under-sampling.

Providing Culturally Competent Care for LGBTQ Youth in School-Based Health Centers: A Needs Assessment to Guide Quality of Care Improvements.

PubMed

Garbers, Samantha; Heck, Craig J; Gold, Melanie A; Santelli, John S; Bersamin, Melina

2017-01-01

School-based health centers (SBHCs) can take specific steps to provide culturally competent care for lesbian, gay, bisexual, transgender, and queer (LGBTQ) youth, potentially impacting well-being. A needs assessment survey was conducted among a convenience sample of SBHC administrators and medical directors to assess climates and actions supportive of LGBTQ quality medical care. Half (53%) of the SBHCs surveyed ( N = 66) reviewed print materials for negative LGBTQ stereotypes, and 27.3% conducted exhaustive materials review. Regional differences were detected: 46.2% of Southern SBHCs conducted any materials review compared to 91.3% in the West and all in the East and Midwest (χ 2 , p < .001). In the last academic year, 45.5% conducted no medical provider trainings, and 54.5% conducted no general staff trainings on providing care for LGBTQ youth. On intake forms, 85.4% included preferred names, but only 23.5% included preferred pronoun. There are significant gaps in the extent to which SBHCs provide culturally competent care. These findings can guide future training and advocacy.

History of intelligent transportation systems.

DOT National Transportation Integrated Search

2016-05-01

ITS capabilities have matured significantly over the past 25 years since the ITS Joint Program Office was created, and this document celebrates the advances in this field and explore its exciting future, while also serving as a guide for future ITS r...

Science: Curriculum Guide for Teaching Gifted Children Science in Grades One Through Three: A Sample Ecology Unit.

ERIC Educational Resources Information Center

California State Dept. of Education, Sacramento. Office of Curriculum Services.

The natural science curriculum guide for gifted primary students includes a sample teaching-learning plan for an ecology unit and eight sample lesson plans. Chapter One provides an overview of the unit, a review of behavioral objectives, and a list of concepts and generalizations. The second chapter cites a teaching-learning plan dealing with such…

Future HIV Mentoring Programs to Enhance Diversity.

PubMed

Stoff, David M; Cargill, Victoria A

2016-09-01

This paper proposes a general template to guide future mentoring program development addressing: (i) considerations to ensure an adequate research workforce; (ii) key guidelines and principles of mentoring; and (iii) use of a logic model to develop program milestones, outcomes and evaluation. We focus on these areas to guide and inform the most effective mentoring program components, which we find to be more helpful than identifying specific features and ingredients. Although the focus is on the development of a new generation of investigators from diverse backgrounds, this template may also apply to mentoring programs for other investigators and for disciplines beyond HIV.

Reliability of conventional shade guides in teeth color determination.

PubMed

Todorović, Ana; Todorović, Aleksandar; Gostović, Aleksandra Spadijer; Lazić, Vojkan; Milicić, Biljana; Djurisić, Slobodan

2013-10-01

Color matching in prosthodontic therapy is a very important task because it influences the esthetic value of dental restorations. Visual shade matching represents the most frequently applied method in clinical practice. Instrumental measurements provide objective and quantified data in color assessment of natural teeth and restorations. In instrumental shade analysis, the goal is to achieve the smallest deltaE value possible, indicating the most accurate shade match. The aim of this study was to evaluate the reliability of commercially available ceramic shade guides. VITA Easyshade spectrophotometer (VITA, Germany) was used for instrumental color determination. Utilizing this device, color samples of ten VITA Classical and ten VITA 3D - Master shade guides were analyzed. Each color sample from all shade guides was measured three times and the basic parameters of color quality were examined: deltaL, deltaC, deltaH, deltaE, deltaElc. Based on these parameters spectrophotometer marks the shade matching as good, fair or adjust. After performing 1,248 measurements of ceramic color samples, frequency of evaluations adjust, fair and good were statistically significantly different between VITA Classical and VITA 3D Master shade guides (p = 0.002). There were 27.1% cases scored as adjust, 66.3% as fair and 6.7% as good. In VITA 3D - Master shade guides 30.9% cases were evaluated as adjust, 66.4% as fair and 2.7% cases as good. Color samples from different shade guides, produced by the same manufacturer, show variability in basic color parameters, which once again proves the lack of precision and nonuniformity of the conventional method.

Image-guided surgery and therapy: current status and future directions

NASA Astrophysics Data System (ADS)

Peters, Terence M.

2001-05-01

Image-guided surgery and therapy is assuming an increasingly important role, particularly considering the current emphasis on minimally-invasive surgical procedures. Volumetric CT and MR images have been used now for some time in conjunction with stereotactic frames, to guide many neurosurgical procedures. With the development of systems that permit surgical instruments to be tracked in space, image-guided surgery now includes the use of frame-less procedures, and the application of the technology has spread beyond neurosurgery to include orthopedic applications and therapy of various soft-tissue organs such as the breast, prostate and heart. Since tracking systems allow image- guided surgery to be undertaken without frames, a great deal of effort has been spent on image-to-image and image-to- patient registration techniques, and upon the means of combining real-time intra-operative images with images acquired pre-operatively. As image-guided surgery systems have become increasingly sophisticated, the greatest challenges to their successful adoption in the operating room of the future relate to the interface between the user and the system. To date, little effort has been expended to ensure that the human factors issues relating to the use of such equipment in the operating room have been adequately addressed. Such systems will only be employed routinely in the OR when they are designed to be intuitive, unobtrusive, and provide simple access to the source of the images.

Welder's Helper. Coordinator's Guide. Individualized Study Guide. General Metal Trades.

ERIC Educational Resources Information Center

Dean, James W.

This guide provides information to enable coordinators to direct learning activities for students using an individualized study guide on being a welder's helper. The study material is designed for students enrolled in cooperative part-time training and employed, or desiring to be employed, as welders' helpers. Contents include a sample progress…

Home Economics: Child Development. Secondary Schools. Curriculum Guide.

ERIC Educational Resources Information Center

Trust Territory of the Pacific Islands Dept. of Education, Saipan.

This document, a curriculum guide in home economics on child development, for secondary schools, is one of six guides developed for inservice teachers at Marianas High School in Saipan. The guide provides the rationale, description, goals and objectives of the program; the program of studies and performance objectives by levels; samples of lesson…

Lathe Operator. Coordinator's Guide. Individualized Study Guide. General Metal Trades.

ERIC Educational Resources Information Center

East Texas State Univ., Commerce. Occupational Curriculum Lab.

This guide provides information to enable coordinators to direct learning activities for students using an individualized study guide on operating a lathe. The study material is designed for students enrolled in cooperative part-time training and employed, or desiring to be employed, as lathe operators. Contents include a sample progress chart,…

Optimization of a multi-channel parabolic guide for the material science diffractometer STRESS-SPEC at FRM II

NASA Astrophysics Data System (ADS)

Rebelo Kornmeier, Joana; Ostermann, Andreas; Hofmann, Michael; Gibmeier, Jens

2014-02-01

Neutron strain diffractometers usually use slits to define a gauge volume within engineering samples. In this study a multi-channel parabolic neutron guide was developed to be used instead of the primary slit to minimise the loss of intensity and vertical definition of the gauge volume when using slits placed far away from the measurement position in bulky components. The major advantage of a focusing guide is that the maximum flux is not at the exit of the guide as for a slit system but at the focal point relatively far away from the exit of the guide. Monte Carlo simulations were used to optimise the multi-channel parabolic guide with respect to the instrument characteristics of the diffractometer STRESS-SPEC at the FRM II neutron source. Also the simulations are in excellent agreement with experimental measurements using the optimised multi-channel parabolic guide at the neutron diffractometer. In addition the performance of the guide was compared to the standard slit setup at STRESS-SPEC using a single bead weld sample used in earlier round robin tests for residual strain measurements.

The importance of sampling standardization for comparisons of insect herbivory in deep time: a case study from the late Palaeozoic

NASA Astrophysics Data System (ADS)

Schachat, Sandra R.; Labandeira, Conrad C.; Maccracken, S. Augusta

2018-03-01

Sampling standardization has not been fully addressed for the study of insect herbivory in the fossil record. The effects of sampling within a single locality were explored almost a decade ago, but the importance of sampling standardization for comparisons of herbivory across space and time has not yet been evaluated. Here, we present a case study from the Permian in which we evaluate the impact of sampling standardization on comparisons of insect herbivory from two localities that are similar in age and floral composition. Comparisons of insect damage type (DT) diversity change dramatically when the number of leaves examined is standardized by surface area. This finding suggests that surface area should always be taken into account for comparisons of DT diversity. In addition, the three most common metrics of herbivory-DT diversity, proportion of leaves herbivorized and proportion of leaf surface area herbivorized-are inherently decoupled from each other. The decoupling of the diversity and intensity of insect herbivory necessitates a reinterpretation of published data because they had been conflated in previous studies. Future studies should examine the divergent ecological factors that underlie these metrics. We conclude with suggestions to guide the sampling and analysis of herbivorized leaves in the fossil record.

The Impacts of Oil Palm on Recent Deforestation and Biodiversity Loss

PubMed Central

Pimm, Stuart L.; Jenkins, Clinton N.; Smith, Sharon J.

2016-01-01

Palm oil is the most widely traded vegetable oil globally, with demand projected to increase substantially in the future. Almost all oil palm grows in areas that were once tropical moist forests, some of them quite recently. The conversion to date, and future expansion, threatens biodiversity and increases greenhouse gas emissions. Today, consumer pressure is pushing companies toward deforestation-free sources of palm oil. To guide interventions aimed at reducing tropical deforestation due to oil palm, we analysed recent expansions and modelled likely future ones. We assessed sample areas to find where oil palm plantations have recently replaced forests in 20 countries, using a combination of high-resolution imagery from Google Earth and Landsat. We then compared these trends to countrywide trends in FAO data for oil palm planted area. Finally, we assessed which forests have high agricultural suitability for future oil palm development, which we refer to as vulnerable forests, and identified critical areas for biodiversity that oil palm expansion threatens. Our analysis reveals regional trends in deforestation associated with oil palm agriculture. In Southeast Asia, 45% of sampled oil palm plantations came from areas that were forests in 1989. For South America, the percentage was 31%. By contrast, in Mesoamerica and Africa, we observed only 2% and 7% of oil palm plantations coming from areas that were forest in 1989. The largest areas of vulnerable forest are in Africa and South America. Vulnerable forests in all four regions of production contain globally high concentrations of mammal and bird species at risk of extinction. However, priority areas for biodiversity conservation differ based on taxa and criteria used. Government regulation and voluntary market interventions can help incentivize the expansion of oil palm plantations in ways that protect biodiversity-rich ecosystems. PMID:27462984

The Impacts of Oil Palm on Recent Deforestation and Biodiversity Loss.

PubMed

Vijay, Varsha; Pimm, Stuart L; Jenkins, Clinton N; Smith, Sharon J

2016-01-01

Palm oil is the most widely traded vegetable oil globally, with demand projected to increase substantially in the future. Almost all oil palm grows in areas that were once tropical moist forests, some of them quite recently. The conversion to date, and future expansion, threatens biodiversity and increases greenhouse gas emissions. Today, consumer pressure is pushing companies toward deforestation-free sources of palm oil. To guide interventions aimed at reducing tropical deforestation due to oil palm, we analysed recent expansions and modelled likely future ones. We assessed sample areas to find where oil palm plantations have recently replaced forests in 20 countries, using a combination of high-resolution imagery from Google Earth and Landsat. We then compared these trends to countrywide trends in FAO data for oil palm planted area. Finally, we assessed which forests have high agricultural suitability for future oil palm development, which we refer to as vulnerable forests, and identified critical areas for biodiversity that oil palm expansion threatens. Our analysis reveals regional trends in deforestation associated with oil palm agriculture. In Southeast Asia, 45% of sampled oil palm plantations came from areas that were forests in 1989. For South America, the percentage was 31%. By contrast, in Mesoamerica and Africa, we observed only 2% and 7% of oil palm plantations coming from areas that were forest in 1989. The largest areas of vulnerable forest are in Africa and South America. Vulnerable forests in all four regions of production contain globally high concentrations of mammal and bird species at risk of extinction. However, priority areas for biodiversity conservation differ based on taxa and criteria used. Government regulation and voluntary market interventions can help incentivize the expansion of oil palm plantations in ways that protect biodiversity-rich ecosystems.

Exoplanet Biosignatures: Future Directions

PubMed Central

Bains, William; Cronin, Leroy; DasSarma, Shiladitya; Danielache, Sebastian; Domagal-Goldman, Shawn; Kacar, Betul; Kiang, Nancy Y.; Lenardic, Adrian; Reinhard, Christopher T.; Moore, William; Schwieterman, Edward W.; Shkolnik, Evgenya L.; Smith, Harrison B.

2018-01-01

Abstract We introduce a Bayesian method for guiding future directions for detection of life on exoplanets. We describe empirical and theoretical work necessary to place constraints on the relevant likelihoods, including those emerging from better understanding stellar environment, planetary climate and geophysics, geochemical cycling, the universalities of physics and chemistry, the contingencies of evolutionary history, the properties of life as an emergent complex system, and the mechanisms driving the emergence of life. We provide examples for how the Bayesian formalism could guide future search strategies, including determining observations to prioritize or deciding between targeted searches or larger lower resolution surveys to generate ensemble statistics and address how a Bayesian methodology could constrain the prior probability of life with or without a positive detection. Key Words: Exoplanets—Biosignatures—Life detection—Bayesian analysis. Astrobiology 18, 779–824. PMID:29938538

Exoplanet Biosignatures: Future Directions.

PubMed

Walker, Sara I; Bains, William; Cronin, Leroy; DasSarma, Shiladitya; Danielache, Sebastian; Domagal-Goldman, Shawn; Kacar, Betul; Kiang, Nancy Y; Lenardic, Adrian; Reinhard, Christopher T; Moore, William; Schwieterman, Edward W; Shkolnik, Evgenya L; Smith, Harrison B

2018-06-01

We introduce a Bayesian method for guiding future directions for detection of life on exoplanets. We describe empirical and theoretical work necessary to place constraints on the relevant likelihoods, including those emerging from better understanding stellar environment, planetary climate and geophysics, geochemical cycling, the universalities of physics and chemistry, the contingencies of evolutionary history, the properties of life as an emergent complex system, and the mechanisms driving the emergence of life. We provide examples for how the Bayesian formalism could guide future search strategies, including determining observations to prioritize or deciding between targeted searches or larger lower resolution surveys to generate ensemble statistics and address how a Bayesian methodology could constrain the prior probability of life with or without a positive detection. Key Words: Exoplanets-Biosignatures-Life detection-Bayesian analysis. Astrobiology 18, 779-824.

A guide to soil samplng and analysis on the National Forests of the Inland Northwest United States

Treesearch

Deb Page-Dumroese; Al Harvey; Marty Jurgensen

1995-01-01

This guide details soil collection methods, sample analysis, and data translation. It outlines what field soil scientists need to make accurate interpretations of site information. Included are instructions for sampling typical Andisols found on National Forests of the Inland Northwest United States.

Graphical correlation of gaging-station records

USGS Publications Warehouse

Searcy, James K.

1960-01-01

A gaging-station record is a sample of the rate of flow of a stream at a given site. This sample can be used to estimate the magnitude and distribution of future flows if the record is long enough to be representative of the long-term flow of the stream. The reliability of a short-term record for estimating future flow characteristics can be improved through correlation with a long-term record. Correlation can be either numerical or graphical, but graphical correlation of gaging-station records has several advantages. The graphical correlation method is described in a step-by-step procedure with an illustrative problem of simple correlation, illustrative problems of three examples of multiple correlation--removing seasonal effect--and two examples of correlation of one record with two other records. Except in the problem on removal of seasonal effect, the same group of stations is used in the illustrative problems. The purpose of the problems is to illustrate the method--not to show the improvement that can result from multiple correlation as compared with simple correlation. Hydrologic factors determine whether a usable relation exists between gaging-station records. Statistics is only a tool for evaluating and using an existing relation, and the investigator must be guided by a knowledge of hydrology.

Zeiss ΣIGMA VP-FE-SEM User Guide

EPA Science Inventory

User guide for analyzing carbon based nanomaterials on a Zeiss Sigma microscope. The guide includes helpful steps for sample preparation and loading. Specific topics utilizing the scanning electron microscope are instrumentation startup and imagining. A variety of detectors in...

Northern Forest Futures reporting tools and database guide

Treesearch

Patrick D. Miles; Robert J. Huggett; W. Keith Moser

2015-01-01

The Northern Forest Futures database (NFFDB) supports the reporting of both current and projected future forest conditions for the 20 states that make up the U.S. North, an area bounded by Maine, Maryland, Missouri, and Minnesota. The NFFDB database and attendant reporting tools are available to the public as a Microsoft AccessTM database. The...

Conclusions: The Future of Family Involvement in Schools in African-American Communities

ERIC Educational Resources Information Center

Juhasz, Anne

2004-01-01

This article talks about the future of family involvement in schools in African-American communities. The future of family involvement in the schools rests with today's teachers and parents who will take what they learned from the past, establish the philosophical foundations to guide their interactions, incorporate child and family theory and…

Recruiting future neuroscientists: what asking the recruits can teach us.

PubMed

Willcockson, Irmgard U; Phelps, Cynthia L

2004-12-01

Many different strategies are used to recruit students into scientific research careers, including neuroscience research. These strategies are rarely based on knowledge about students; instead, activities are selected based on their ease of implementation. The goal of the LEARN Project is to encourage high school students into mental health science research using the theme of learning and memory. One intervention the authors developed is five Web-based biographies introducing students to contemporary neuroscientist role models studying learning and memory. To guide the design of this intervention, the authors created a survey to determine where students obtain career information and who and what influences their career selection. In a convenience sample of 124 students, the authors found that almost all students use the Internet for information about careers, in addition to consulting family members and teachers. Students' career selections are influenced most by family members, teachers, and people already in the field. The most important factors students look for in their future career are money, fun, and a good match between current interests and future careers. The data affirm the value of outreach efforts that go beyond students to include a broader audience of parents and teachers who play a critical role in career selection.

Automated Circulation Systems in Libraries Serving the Blind and Physically Handicapped: A Reference Guide for Planning.

ERIC Educational Resources Information Center

Wanger, Judith; And Others

Designed to facilitate communications in future automation projects between library and data processing personnel, especially those projects involving the use of automated systems in the service of disabled patrons, this guide identifies and describes a master set of major circulation system requirements and design considerations, and illustrates…

Conservation in a World of Six Billion: A Grassroots Action Guide.

ERIC Educational Resources Information Center

Hren, Benedict J.

This grassroots action guide features a conservation initiative working to bring the impacts of human population growth, economic development, and natural resource consumption into balance with the limits of nature for the benefit of current and future generations. Contents include information sheets entitled "Six Billion People and Growing,""The…

Science 9. DeSoto Parish Curriculum Guide.

ERIC Educational Resources Information Center

DeSoto Parish School Board, Mansfield, LA.

This guide is designed to aid the teacher in planning and teaching a ninth-grade science course. It should provide students with a functional system of knowledge which is applicable to new situations and will serve as the basis for future decisions. Five units outlined are entitled: Introduction to Service; The Earth's Storehouse; The Earth's…

Employment in Agribusiness. Teacher Edition. Second Edition.

ERIC Educational Resources Information Center

Crummett, Dan M.; Newport, Alan K.

This curriculum guide is designed to help teachers prepare students with the variety of skills that will help them obtain jobs that can turn into rewarding careers in agribusiness. The guide also serves as a resource for students participating in agricultural sales and service competitions sponsored by student organizations such as Future Farmers…

Building for the Future: Nutrition Guidance for the Child Nutrition Programs.

ERIC Educational Resources Information Center

Food and Nutrition Service (USDA), Washington, DC.

This publication offers practical guidance to help food service professionals provide sound nutrition to America's children and serves as a basis for the revision of U.S. Department of Agriculture meal patterns, menu planning guides, and the development of new recipes. The guide is organized into two sections. The first, "Implementation of…

Chapter Innovators Guide, 2000: Models of Innovation Award Winners.

ERIC Educational Resources Information Center

National FFA Organization, Indianapolis, IN.

This guide presents the Future Farmers of America (FFA) 2000 Model of Innovation award winners' projects. Chapters demonstrated abilities to identify goals and objectives, create a workable plan of action, attain and evaluate results, and identify items learned and ways to improve. Chapter 1 discusses the FFA National Chapter Award program that…

Business and Personal Services Marketing, With an Emphasis on Entrepreneurial Opportunities. A Guide.

ERIC Educational Resources Information Center

Luter, Robert R.

This publication, one of a series of self-contained instructional manuals for students in marketing and distribution, deals with the field of personal services marketing and covers job opportunities, career possibilities, and future planning for entrepreneurship. Addressed in the individual units of the guide are the following topics: the business…

X-Rays: The Inside Story (Secondary). Teacher's Guide.

ERIC Educational Resources Information Center

Royal Australasian Coll. of Radiologists, Sydney (Australia).

The goals of this unit are to explore the magic, history, and development of imaging technology, clarify what X-rays and radiation are, examine the issues involved in imaging technology, understand basic anatomy, explore careers related to radiology, and promote future good health. Included in the unit are the teacher's guide, a collection of…

Recycle Alaska: Reduce, Reuse, Recycle. Activities Handbook, Teacher's Guide, and Student Worksheets.

ERIC Educational Resources Information Center

Alaska State Dept. of Education, Juneau.

Recycling is a very important aspect of conserving the environment for future generations. This guide addresses the topic of litter prevention for the Alaskan environment and contains 42 activities. Activity topics covered include Natural Cycles, Human Interruption of Natural Cycles, Reduce, Reuse, Recycle and Recycled Classroom. Grade level,…

A Plan to the Future in Home Economics Education. Draft Curriculum.

ERIC Educational Resources Information Center

Ruckes, Nina Tiglio; Mongillo, Michael

This curriculum guide was prepared to help Connecticut high schools offer an opportunity to disadvantaged high school students who are interested in home economics education to earn some college credit toward a degree in dietetic technology. The curriculum guide includes an overview of the course with a course description, recommended textbooks,…

A Guide to Assessing Urban Forests

Treesearch

David Nowak

2013-01-01

Urban forests provide numerous ecosystem services. To quantify these services and guide management to sustain these services for future generations, the structure or composition of the forest must be assessed. There are two basic ways of assessing the structure or composition of the urban forest: Bottom-up approach. Field-based assessments to measure the physical...

NED-2 User's Guide

Treesearch

Mark J. Twery; Peter D. Knopp; Scott A. Thomasma; Donald E. Nute

2011-01-01

This is the user's guide for NED-2, which is the latest version of NED, a forest ecosystem management decision support system. This software is part of a family of software products intended to help resource managers develop goals, assess current and future conditions, and produce sustainable management plans for forest properties. Designed for stand-alone Windows...

NED-2 reference guide

Treesearch

Mark J. Twery; Peter D. Knopp; Scott A. Thomasma; Donald E. Nute

2012-01-01

This is the reference guide for NED-2, which is the latest version of NED, a forest ecosystem management decision support system. This software is part of a family of software products intended to help resource managers develop goals, assess current and future conditions, and produce sustainable management plans for forest properties. Designed for stand-alone Windows-...

Ohio Environmental Education Areas.

ERIC Educational Resources Information Center

Melvin, Ruth W.

This is a guide to regional sites in Ohio which can be studied in regard to resource management; land use; the quality of air, water, soil; and reclamation. The first section of the guide includes brief descriptions of Ohio's natural features at the present time, accounts of past appearances and events, and predictions for the future. In the…

Lung Cancer Screening Participation: Developing a Conceptual Model to Guide Research

PubMed Central

Carter-Harris, Lisa; Davis, Lorie L.; Rawl, Susan M.

2017-01-01

Purpose To describe the development of a conceptual model to guide research focused on lung cancer screening participation from the perspective of the individual in the decision-making process. Methods Based on a comprehensive review of empirical and theoretical literature, a conceptual model was developed linking key psychological variables (stigma, medical mistrust, fatalism, worry, and fear) to the health belief model and precaution adoption process model. Results Proposed model concepts have been examined in prior research of either lung or other cancer screening behavior. To date, a few studies have explored a limited number of variables that influence screening behavior in lung cancer specifically. Therefore, relationships among concepts in the model have been proposed and future research directions presented. Conclusion This proposed model is an initial step to support theoretically based research. As lung cancer screening becomes more widely implemented, it is critical to theoretically guide research to understand variables that may be associated with lung cancer screening participation. Findings from future research guided by the proposed conceptual model can be used to refine the model and inform tailored intervention development. PMID:28304262

Lung Cancer Screening Participation: Developing a Conceptual Model to Guide Research.

PubMed

Carter-Harris, Lisa; Davis, Lorie L; Rawl, Susan M

2016-11-01

To describe the development of a conceptual model to guide research focused on lung cancer screening participation from the perspective of the individual in the decision-making process. Based on a comprehensive review of empirical and theoretical literature, a conceptual model was developed linking key psychological variables (stigma, medical mistrust, fatalism, worry, and fear) to the health belief model and precaution adoption process model. Proposed model concepts have been examined in prior research of either lung or other cancer screening behavior. To date, a few studies have explored a limited number of variables that influence screening behavior in lung cancer specifically. Therefore, relationships among concepts in the model have been proposed and future research directions presented. This proposed model is an initial step to support theoretically based research. As lung cancer screening becomes more widely implemented, it is critical to theoretically guide research to understand variables that may be associated with lung cancer screening participation. Findings from future research guided by the proposed conceptual model can be used to refine the model and inform tailored intervention development.

Preparing a Book Review: A Research Guide; Preparing a Term Project: A Research Guide; Preparing a Written or Oral Presentation: A Research Guide.

ERIC Educational Resources Information Center

Weil, Martha A.

These three research guides present guidelines and sample exercises to help students at Washburn University of Topeka in Kansas use the library in preparing a book review, a term project, and a written or oral presentation. The guide on book reviews provides suggestions and exercises for choosing a book and finding information on the book, its…

Principles of Marketing. A One-Semester Cluster Course for Marketing Education. Curriculum Guide.

ERIC Educational Resources Information Center

Cockrum, Jim

This curriculum guide was developed to help teachers use the new textbook adopted by Texas in 1991-92 for teaching the 1-semester Principles of Marketing course. The guide is organized in four sections. The first section contains information on using the curriculum guide, including an overview, sample lesson plans and other worksheets, suggestions…

Self-objectification and disordered eating: A meta-analysis.

PubMed

Schaefer, Lauren M; Thompson, J Kevin

2018-06-01

Objectification theory posits that self-objectification increases risk for disordered eating. The current study sought to examine the relationship between self-objectification and disordered eating using meta-analytic techniques. Data from 53 cross-sectional studies (73 effect sizes) revealed a significant moderate positive overall effect (r = .39), which was moderated by gender, ethnicity, sexual orientation, and measurement of self-objectification. Specifically, larger effect sizes were associated with female samples and the Objectified Body Consciousness Scale. Effect sizes were smaller among heterosexual men and African American samples. Age, body mass index, country of origin, measurement of disordered eating, sample type and publication type were not significant moderators. Overall, results from the first meta-analysis to examine the relationship between self-objectification and disordered eating provide support for one of the major tenets of objectification theory and suggest that self-objectification may be a meaningful target in eating disorder interventions, though further work is needed to establish temporal and causal relationships. Findings highlight current gaps in the literature (e.g., limited representation of males, and ethnic and sexual minorities) with implications for guiding future research. © 2018 Wiley Periodicals, Inc.

Elevated genetic structure in the coastal tailed frog (Ascaphus truei) in managed redwood forests.

PubMed

Aguilar, Andres; Douglas, Robert B; Gordon, Eric; Baumsteiger, Jason; Goldsworthy, Matthew O

2013-03-01

Landscape alterations have dramatic impacts on the distribution of genetic variation within and among populations and understanding these effects can guide contemporary and future conservation strategies. We initiated a landscape-scale genetic study of the coastal tailed frog (Ascaphus truei) on commercial timberlands within the southern range of the species in Mendocino County (CA, USA). In total, 294 individuals from 13 populations were analyzed at 9 microsatellite loci. None of the sampled populations departed from mutation-drift equilibrium, indicating recent population bottlenecks were not detected in contemporary samples. Fine-scale analysis indicated sampled populations were structured at the watershed level (mean F (ST) = 0.077 and mean G'(ST) = 0.425). Landscape analyses suggested wet and moist areas may serve as significant corridors for gene flow within watersheds in this region (r (2) = 0.32-0.54 for moisture-related features). Results indicate populations of frogs may have persisted at this scale through intense periods of timber harvest, making southern range edge populations of coastal tailed frogs resilient to past land use practices.

Novel hybrid cryo-radial method: an emerging alternative to CT-guided biopsy in suspected lung cancer. A prospective case series and description of technique.

PubMed

Herath, Samantha; Yap, Elaine

2018-02-01

In diagnosing peripheral pulmonary lesions (PPL), radial endobronchial ultrasound (R-EBUS) is emerging as a safer method in comparison to CT-guided biopsy. Despite the better safety profile, the yield of R-EBUS remains lower (73%) than CT-guided biopsy (90%) due to the smaller size of samples. We adopted a hybrid method by adding cryobiopsy via the R-EBUS Guide Sheath (GS) to produce larger, non-crushed samples to improve diagnostic capability and enhance molecular testing. We report six prospective patients who underwent this procedure in our institution. R-EBUS samples were obtained via conventional sampling methods (needle aspiration, forceps biopsy, and cytology brush), followed by a cryobiopsy. An endobronchial blocker was placed near the planned area of biopsy in advance and inflated post-biopsy to minimize the risk of bleeding in all patients. A chest X-ray was performed 1 h post-procedure. All the PPLs were visualized with R-EBUS. The mean diameter of cryobiopsy samples was twice the size of forceps biopsy samples. In four patients, cryobiopsy samples were superior in size and the number of malignant cells per high power filed and was the preferred sample selected for mutation analysis and molecular testing. There was no pneumothorax or significant bleeding to report. Cryobiopsy samples were consistently larger and were the preferred samples for molecular testing, with an increase in the diagnostic yield and reduction in the need for repeat procedures, without hindering the marked safety profile of R-EBUS. Using an endobronchial blocker improves the safety of this procedure.

Space Launch System (SLS) Mission Planner's Guide

NASA Technical Reports Server (NTRS)

Smith, David Alan

2017-01-01

The purpose of this Space Launch System (SLS) Mission Planner's Guide (MPG) is to provide future payload developers/users with sufficient insight to support preliminary SLS mission planning. Consequently, this SLS MPG is not intended to be a payload requirements document; rather, it organizes and details SLS interfaces/accommodations in a manner similar to that of current Expendable Launch Vehicle (ELV) user guides to support early feasibility assessment. Like ELV Programs, once approved to fly on SLS, specific payload requirements will be defined in unique documentation.

Focused conformational sampling in proteins

NASA Astrophysics Data System (ADS)

Bacci, Marco; Langini, Cassiano; Vymětal, Jiří; Caflisch, Amedeo; Vitalis, Andreas

2017-11-01

A detailed understanding of the conformational dynamics of biological molecules is difficult to obtain by experimental techniques due to resolution limitations in both time and space. Computer simulations avoid these in theory but are often too short to sample rare events reliably. Here we show that the progress index-guided sampling (PIGS) protocol can be used to enhance the sampling of rare events in selected parts of biomolecules without perturbing the remainder of the system. The method is very easy to use as it only requires as essential input a set of several features representing the parts of interest sufficiently. In this feature space, new states are discovered by spontaneous fluctuations alone and in unsupervised fashion. Because there are no energetic biases acting on phase space variables or projections thereof, the trajectories PIGS generates can be analyzed directly in the framework of transition networks. We demonstrate the possibility and usefulness of such focused explorations of biomolecules with two loops that are part of the binding sites of bromodomains, a family of epigenetic "reader" modules. This real-life application uncovers states that are structurally and kinetically far away from the initial crystallographic structures and are also metastable. Representative conformations are intended to be used in future high-throughput virtual screening campaigns.

A user-centered model for designing consumer mobile health (mHealth) applications (apps).

PubMed

Schnall, Rebecca; Rojas, Marlene; Bakken, Suzanne; Brown, William; Carballo-Dieguez, Alex; Carry, Monique; Gelaude, Deborah; Mosley, Jocelyn Patterson; Travers, Jasmine

2016-04-01

Mobile technologies are a useful platform for the delivery of health behavior interventions. Yet little work has been done to create a rigorous and standardized process for the design of mobile health (mHealth) apps. This project sought to explore the use of the Information Systems Research (ISR) framework as guide for the design of mHealth apps. Our work was guided by the ISR framework which is comprised of 3 cycles: Relevance, Rigor and Design. In the Relevance cycle, we conducted 5 focus groups with 33 targeted end-users. In the Rigor cycle, we performed a review to identify technology-based interventions for meeting the health prevention needs of our target population. In the Design Cycle, we employed usability evaluation methods to iteratively develop and refine mock-ups for a mHealth app. Through an iterative process, we identified barriers and facilitators to the use of mHealth technology for HIV prevention for high-risk MSM, developed 'use cases' and identified relevant functional content and features for inclusion in a design document to guide future app development. Findings from our work support the use of the ISR framework as a guide for designing future mHealth apps. Results from this work provide detailed descriptions of the user-centered design and system development and have heuristic value for those venturing into the area of technology-based intervention work. Findings from this study support the use of the ISR framework as a guide for future mHealth app development. Use of the ISR framework is a potentially useful approach for the design of a mobile app that incorporates end-users' design preferences. Copyright © 2016 Elsevier Inc. All rights reserved.

Educational Planning for the Future Development of Pasco-Hernando Community College.

ERIC Educational Resources Information Center

McGuffey, C. W.; And Others

The purpose of this study was to develop a long-range educational plan for the future development and expansion of the current program and facilities of Pasco-Hernando Community College. An analysis has been made of available data and related information as a basis for the preparation of a generalized plan to guide the future development of the…

Application of the coastal generalized ecosystem model (CGEM) to assess the impacts of a potential future climate scenario on northern Gulf of Mexico hypoxia

EPA Science Inventory

Mechanistic hypoxia models for the northern Gulf of Mexico are being used to guide policy goals for Mississippi River nutrient loading reductions. However, to date, these models have not examined the effects of both nutrient loads and future climate. Here, we simulate a future c...

iTunes song-gifting is a low-cost, efficient recruitment tool to engage high-risk MSM in internet research.

PubMed

Holland, Christine M; Ritchie, Natalie D; Du Bois, Steve N

2015-10-01

This brief report describes methodology and results of a novel, efficient, and low-cost recruitment tool to engage high-risk MSM in online research. We developed an incentivization protocol using iTunes song-gifting to encourage participation of high-risk MSM in an Internet-based survey of HIV status, childhood sexual abuse, and adult behavior and functioning. Our recruitment methodology yielded 489 participants in 4.5 months at a total incentive cost of $1.43USD per participant. The sample comprised a critically high-risk group of MSM, including 71.0 % who reported recent condomless anal intercourse. We offer a "how-to" guide to aid future investigators in using iTunes song-gifting incentives.

UROLOGIC ROBOTS AND FUTURE DIRECTIONS

PubMed Central

Mozer, Pierre; Troccaz, Jocelyne; Stoianovici, Dan

2009-01-01

Purpose of review Robot-assisted laparoscopic surgery in urology has gained immense popularity with the Da Vinci system but a lot of research teams are working on new robots. The purpose of this paper is to review current urologic robots and present future developments directions. Recent findings Future systems are expected to advance in two directions: improvements of remote manipulation robots and developments of image-guided robots. Summary The final goal of robots is to allow safer and more homogeneous outcomes with less variability of surgeon performance, as well as new tools to perform tasks based on medical transcutaneous imaging, in a less invasive way, at lower costs. It is expected that improvements for remote system could be augmented reality, haptic feed back, size reduction and development of new tools for NOTES surgery. The paradigm of image-guided robots is close to a clinical availability and the most advanced robots are presented with end-user technical assessments. It is also notable that the potential of robots lies much further ahead than the accomplishments of the daVinci system. The integration of imaging with robotics holds a substantial promise, because this can accomplish tasks otherwise impossible. Image guided robots have the potential to offer a paradigm shift. PMID:19057227

Urologic robots and future directions.

PubMed

Mozer, Pierre; Troccaz, Jocelyne; Stoianovici, Dan

2009-01-01

Robot-assisted laparoscopic surgery in urology has gained immense popularity with the daVinci system, but a lot of research teams are working on new robots. The purpose of this study is to review current urologic robots and present future development directions. Future systems are expected to advance in two directions: improvements of remote manipulation robots and developments of image-guided robots. The final goal of robots is to allow safer and more homogeneous outcomes with less variability of surgeon performance, as well as new tools to perform tasks on the basis of medical transcutaneous imaging, in a less invasive way, at lower costs. It is expected that improvements for a remote system could be augmented in reality, with haptic feedback, size reduction, and development of new tools for natural orifice translumenal endoscopic surgery. The paradigm of image-guided robots is close to clinical availability and the most advanced robots are presented with end-user technical assessments. It is also notable that the potential of robots lies much further ahead than the accomplishments of the daVinci system. The integration of imaging with robotics holds a substantial promise, because this can accomplish tasks otherwise impossible. Image-guided robots have the potential to offer a paradigm shift.

Exploring the Moon: A teacher's guide with activities for Earth and space sciences

NASA Technical Reports Server (NTRS)

Taylor, G. Jeffrey; Martel, Linda M. V.; Bays, Brooks G., Jr.

1994-01-01

This guide contains educational materials designed for use in upper elementary through high schools with the Lunar Sample Disk. A set of thirty-six 35-mm slides complements the activities in this guidebook. The book contains: (1) information on the Lunar Sample Disk; (2) a curriculum content matrix; (3) a teacher's guide; (4) moon ABC's fact sheet; (5) rock ABC's fact sheet; (6) progress in Lunar Science chart; (7) seventeen activities; (8) a resource section for each unit; (9) a glossary; and (10) a list of NASA educational resources.

A guide to the use of distance sampling to estimate abundance of Karner blue butterflies

USGS Publications Warehouse

Grundel, Ralph

2015-01-01

This guide is intended to describe the use of distance sampling as a method for evaluating the abundance of Karner blue butterflies at a location. Other methods for evaluating abundance exist, including mark-release-recapture and index counts derived from Pollard-Yates surveys, for example. Although this guide is not intended to be a detailed comparison of the pros and cons of each type of method, there are important preliminary considerations to think about before selecting any method for evaluating the abundance of Karner blue butterflies.

MoonDB: Restoration and Synthesis of Lunar Petrological and Geochemical Data

NASA Technical Reports Server (NTRS)

Lehnert, Kerstin A.; Cai, Yue; Mana, Sara; Todd, Nancy S.; Zeigler, Ryan A.; Evans, Cindy A.

2016-01-01

About 2,200 samples were collected from the Moon during the Apollo missions, forming a unique and irreplaceable legacy of the Apollo program. These samples, obtained at tremendous cost and great risk, are the only samples that have ever been returned by astronauts from the surface of another planetary body. These lunar samples have been curated at NASA Johnson Space Center and made available to the global research community. Over more than 45 years, a vast body of petrological, geochemical, and geochronological studies of these samples have been amassed, which helped to expand our understanding of the history and evolution of the Moon, the Earth itself, and the history of our entire solar system. Unfortunately, data from these studies are dispersed in the literature, often only available in analog format in older publications, and/or lacking sample metadata and analytical metadata (e.g., information about analytical procedure and data quality), which greatly limits their usage for new scientific endeavors. Even worse is that much lunar data have never been published, simply because no forum existed at the time (e.g., electronic supplements). Thousands of valuable analyses remain inaccessible, often preserved only in personal records, and are in danger of being lost forever, when investigators retire or pass away. Making these data and metadata publicly accessible in a digital format would dramatically help guide current and future research and eliminate duplicated analyses of precious lunar samples.

A School Leader's Guide to Improving the Achievement, Assimilation, and Involvement of Montagnard Children

ERIC Educational Resources Information Center

Jazzar, Michael; Hamm, Carl

2007-01-01

Following an illustrious introduction to the Montagnards and their plight and flight to the United States, this study explores the education, assimilation, and future development of Montagnard students into American schools. A guide for school leaders is presented within this study to assist the Montagnard students in overcoming obstacles and…

How to Co-Teach: A Guide for General and Special Educators

ERIC Educational Resources Information Center

Potts, Elizabeth A.; Howard, Lori A.

2011-01-01

What does good co-teaching look like in an inclusive classroom, and how can a general and special educator build a strong, respectful, and productive partnership? Find out in this introductory how-to guide, ideal for helping current and future co-teachers minimize conflict, maximize teamwork, and ensure the best outcomes for all students in Grades…

Sustainable Development. Teacher's Guide to World Resources. Comprehensive Coursework on the Global Environment.

ERIC Educational Resources Information Center

Snyder, Sarah A.

This teacher's guide presents teaching suggestions and presentation materials about sustainable development, important trends that could lead to human and environmental disasters in the future if they continue unchecked, and how each country has a different path to sustainable development. The lesson is divided into six parts and may be completed…

A Guide for Planning Facilities for Vocational Agriculture in Texas.

ERIC Educational Resources Information Center

Hindman, Neal; Eggenberger, Lewis

A guide to assist those concerned in planning adequate, well-designed facilities for departments of vocational agriculture that will serve their communities in the future. The program of vocational agriculture is an integral part of the total educational program of a school and considerable thought and careful study should be given to locating the…

Learning with Intangible Heritage for a Sustainable Future: Guidelines for Educators in the Asia-Pacific Region

ERIC Educational Resources Information Center

Pillai, Janet; Achilles, Vanessa

2015-01-01

The guide provides teacher educators and teachers with an understanding of the concept of intangible cultural heritage (ICH) and explains why ICH should be integrated into the curriculum in tandem with the principles and perspectives of Education for Sustainable Development (ESD). This guide explains how the strategic incorporation of ICH elements…

The Energy Films Index. An Educator's Guide to Current Energy Films.

ERIC Educational Resources Information Center

Scherner, Sharon; And Others

This guide cites and describes 241 films on energy. The categories are: general films on energy, conservation of energy, history of energy development, coal, electricity, food and energy, geothermal, natural gas, nuclear energy, oil/petroleum, oil shale, solar energy, tar sands, tidal energy, wind, impacts of energy, and future of energy. For each…

Advancing Universities: The Global City as Guide for Change

ERIC Educational Resources Information Center

Frost, Susan; Chopp, Rebecca; Pozorski, Aimee L.

2004-01-01

The paper considers the past development of the research university in the United States and argues that one way to guide future change is to embrace a new cultural model. Using Emory University as a case study, along with the more general perspectives offered through a close study of eleven other private US universities and data assimilated from…

Kids Food CyberClub. Teacher's Guide. First Edition.

ERIC Educational Resources Information Center

Belyea, Monica

This guide is designed to help teachers educate students to be healthier now and in the future. It presents fun, learner-centered activities about nutrition, food, hunger, and food sources. It offers an overview of each section of the Kids Food CyberClub web site, and classroom activities teachers can use to expand on information students will…

Dorsal Striatal-Midbrain Connectivity in Humans Predicts How Reinforcements Are Used to Guide Decisions

ERIC Educational Resources Information Center

Kahnt, Thorsten; Park, Soyoung Q.; Cohen, Michael X.; Beck, Anne; Heinz, Andreas; Wrase, Jana

2009-01-01

It has been suggested that the target areas of dopaminergic midbrain neurons, the dorsal (DS) and ventral striatum (VS), are differently involved in reinforcement learning especially as actor and critic. Whereas the critic learns to predict rewards, the actor maintains action values to guide future decisions. The different midbrain connections to…

21st Century Skills, Education & Competitiveness: A Resource and Policy Guide

ERIC Educational Resources Information Center

Partnership for 21st Century Skills, 2008

2008-01-01

Americans are deeply concerned about their present and future prospects in a time of economic uncertainty. Policymakers have a make-or-break opening--and an obligation--to chart a new path for public education that will secure the nation's economic competitiveness. This guide summarizes the challenges and opportunities that, if left unaddressed,…

Rise to the Challenge: A Business Guide to Creating a Workforce Investment System That Makes Sense.

ERIC Educational Resources Information Center

2000

This document explains how employers can participate in creating a new workforce investment system that is market driven, comprehensive, portable, accountable, customer focused, responsive, flexible, and customized. The guide details immediate and future steps employers can take at the state and local levels to influence the process of creating a…

Forest pest management in a changing world

Treesearch

Andrew M. Liebhold

2012-01-01

The scope, context and science guiding forest pest management have evolved and are likely to continue changing into the future. Here, I present six areas of advice to guide practitioners in the implementation of forest pest management. First, human dimensions will continue to play a key role in most pest problems and should always be a primary consideration in...

Retailing. Instructor's Guide Sheets and Instructor's Package, Modules R 1-45. Competency-Based Education.

ERIC Educational Resources Information Center

Kentucky State Dept. of Education, Frankfort.

This package contains instructor's guide sheets and student task assignment sheets for Modules R 1-45 of the competency-based curriculum in retailing developed for use in secondary and postsecondary schools in Kentucky. Some of the topics covered in the modules include the following: retailing--past, present, and future; retailing occupations;…

Improved Food Drying and Storage Training Manual.

ERIC Educational Resources Information Center

Zweig, Peter R.; And Others

This manual is intended to serve as a guide for those who are helping future Peace Corps volunteers to acquire basic food drying and storage skills. Included in the guide are lesson outlines and handouts for use in each of the 30 sessions of the course. Representative topics discussed in the individual sessions are scheduling, solar dryers,…

Car Trouble. Teacher's Guide to World Resources. Comprehensive Coursework on the Global Environment.

ERIC Educational Resources Information Center

Snyder, Sarah A.

This teacher's guide presents teaching suggestions and presentation materials on the hidden environmental costs of driving automobiles through examining the history of the automobile and looking to the future for alternatives. The lesson is divided into six parts and may be completed in four or more class periods. Student handouts include: (1)…

The Energy Future Today: Grades 7, 8, 9, Social Studies.

ERIC Educational Resources Information Center

National Science Teachers Association, Washington, DC.

This teacher's guide contains a unit of study for teaching about energy in grades seven, eight, and nine. The guide is self-contained and includes the handouts students need to work out the activity problems. The unit is developed around the concepts of shortage, scarcity, tradeoffs, investment, and decision making. Students develop these concepts…

Idaho Driver Education Administrative Guide.

ERIC Educational Resources Information Center

Idaho State Dept. of Education, Boise.

This guide provides information for school administrators and directors of commercial driver training schools about conducting driver education courses in Idaho. The first part of the guide, which applies to both public schools and commercial schools, covers the following areas: administration, sample letters and forms, instructional time…

Sampling in Qualitative Research

PubMed Central

LUBORSKY, MARK R.; RUBINSTEIN, ROBERT L.

2011-01-01

In gerontology the most recognized and elaborate discourse about sampling is generally thought to be in quantitative research associated with survey research and medical research. But sampling has long been a central concern in the social and humanistic inquiry, albeit in a different guise suited to the different goals. There is a need for more explicit discussion of qualitative sampling issues. This article will outline the guiding principles and rationales, features, and practices of sampling in qualitative research. It then describes common questions about sampling in qualitative research. In conclusion it proposes the concept of qualitative clarity as a set of principles (analogous to statistical power) to guide assessments of qualitative sampling in a particular study or proposal. PMID:22058580

Image guided versus palpation guided core needle biopsy of palpable breast masses: a prospective study

PubMed Central

Hari, Smriti; Kumari, Swati; Srivastava, Anurag; Thulkar, Sanjay; Mathur, Sandeep; Veedu, Prasad Thotton

2016-01-01

Background & objectives: Biopsy of palpable breast masses can be performed manually by palpation guidance or under imaging guidance. Based on retrospective studies, image guided biopsy is considered more accurate than palpation guided breast biopsy; however, these techniques have not been compared prospectively. We conducted this prospective study to verify the superiority and determine the size of beneficial effect of image guided biopsy over palpation guided biopsy. Methods: Over a period of 18 months, 36 patients each with palpable breast masses were randomized into palpation guided and image guided breast biopsy arms. Ultrasound was used for image guidance in 33 patients and mammographic (stereotactic) guidance in three patients. All biopsies were performed using 14 gauge automated core biopsy needles. Inconclusive, suspicious or imaging-histologic discordant biopsies were repeated. Results: Malignancy was found in 30 of 36 women in palpation guided biopsy arm and 27 of 36 women in image guided biopsy arm. Palpation guided biopsy had sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 46.7, 100, 100, 27.3 per cent, respectively, for diagnosing breast cancer. Nineteen of 36 women (52.8%) required repeat biopsy because of inadequate samples (7 of 19), suspicious findings (2 of 19) or imaging-histologic discordance (10 of 19). On repeat biopsy, malignancy was found in all cases of imaging-histologic discordance. Image guided biopsy had 96.3 per cent sensitivity and 100 per cent specificity. There was no case of inadequate sample or imaging-histologic discordance with image guided biopsy. Interpretation & conclusions: Our results showed that in palpable breast masses, image guided biopsy was superior to palpation guided biopsy in terms of sensitivity, false negative rate and repeat biopsy rates. PMID:27488003

Constraining neutron guide optimizations with phase-space considerations

NASA Astrophysics Data System (ADS)

Bertelsen, Mads; Lefmann, Kim

2016-09-01

We introduce a method named the Minimalist Principle that serves to reduce the parameter space for neutron guide optimization when the required beam divergence is limited. The reduced parameter space will restrict the optimization to guides with a minimal neutron intake that are still theoretically able to deliver the maximal possible performance. The geometrical constraints are derived using phase-space propagation from moderator to guide and from guide to sample, while assuming that the optimized guides will achieve perfect transport of the limited neutron intake. Guide systems optimized using these constraints are shown to provide performance close to guides optimized without any constraints, however the divergence received at the sample is limited to the desired interval, even when the neutron transport is not limited by the supermirrors used in the guide. As the constraints strongly limit the parameter space for the optimizer, two control parameters are introduced that can be used to adjust the selected subspace, effectively balancing between maximizing neutron transport and avoiding background from unnecessary neutrons. One parameter is needed to describe the expected focusing abilities of the guide to be optimized, going from perfectly focusing to no correlation between position and velocity. The second parameter controls neutron intake into the guide, so that one can select exactly how aggressively the background should be limited. We show examples of guides optimized using these constraints which demonstrates the higher signal to noise than conventional optimizations. Furthermore the parameter controlling neutron intake is explored which shows that the simulated optimal neutron intake is close to the analytically predicted, when assuming that the guide is dominated by multiple scattering events.

Guide to the US collection of antarctic meteorites 1976-1988 (everything you wanted to know about the meteorite collection). Antarctic Meteorite Newsletter, Volume 13, Number 1

NASA Technical Reports Server (NTRS)

Score, Roberta; Lindstrom, Marilyn M.

1990-01-01

The state of the collection of Antarctic Meteorites is summarized. This guide is intended to assist investigators plan their meteorite research and select and request samples. Useful information is presented for all classified meteorites from 1976 to 1988 collections, as of Sept. 1989. The meteorite collection has grown over 13 years to include 4264 samples of which 2754 have been classified. Most of the unclassified meteorites are ordinary chondrites because the collections have been culled for specimens of special petrologic type. The guide consists of two large classification tables. They are preceded by a list of sample locations and important notes to make the tables understandable.

Novel hybrid cryo‐radial method: an emerging alternative to CT‐guided biopsy in suspected lung cancer. A prospective case series and description of technique

PubMed Central

Yap, Elaine

2017-01-01

In diagnosing peripheral pulmonary lesions (PPL), radial endobronchial ultrasound (R‐EBUS) is emerging as a safer method in comparison to CT‐guided biopsy. Despite the better safety profile, the yield of R‐EBUS remains lower (73%) than CT‐guided biopsy (90%) due to the smaller size of samples. We adopted a hybrid method by adding cryobiopsy via the R‐EBUS Guide Sheath (GS) to produce larger, non‐crushed samples to improve diagnostic capability and enhance molecular testing. We report six prospective patients who underwent this procedure in our institution. R‐EBUS samples were obtained via conventional sampling methods (needle aspiration, forceps biopsy, and cytology brush), followed by a cryobiopsy. An endobronchial blocker was placed near the planned area of biopsy in advance and inflated post‐biopsy to minimize the risk of bleeding in all patients. A chest X‐ray was performed 1 h post‐procedure. All the PPLs were visualized with R‐EBUS. The mean diameter of cryobiopsy samples was twice the size of forceps biopsy samples. In four patients, cryobiopsy samples were superior in size and the number of malignant cells per high power filed and was the preferred sample selected for mutation analysis and molecular testing. There was no pneumothorax or significant bleeding to report. Cryobiopsy samples were consistently larger and were the preferred samples for molecular testing, with an increase in the diagnostic yield and reduction in the need for repeat procedures, without hindering the marked safety profile of R‐EBUS. Using an endobronchial blocker improves the safety of this procedure. PMID:29321931

Tip vortex computer code SRATIP. User's guide

NASA Technical Reports Server (NTRS)

Levy, R.; Lin, S. J.

1985-01-01

This User's Guide applies to the three dimensional viscous flow forward marching analysis, PEPSIG, as used for the calculation of the helicopter tip vortex flow field. The guide presents a discussion of the program flow and subroutines, as well as a list of sample input and output.

Wyoming Mathematics Curriculum Guide, Grades 7-12.

ERIC Educational Resources Information Center

Wyoming State Dept. of Education, Cheyenne.

GRADES OR AGES: 7-12; SUBJECT MATTER: Mathematics. ORGANIZATION AND PHYSICAL APPEARANCE: The guide has an introduction and four chapters: 1) A Sample Mathematics Curriculum; 2) The Exceptional Student in Mathematics; 3) Mathematics Components for Comprehensive Occupational Education; 4) Reference Materials. The guide is printed and spiral bound…

Future Educators' Explaining Voices

ERIC Educational Resources Information Center

de Oliveira, Janaina Minelli; Caballero, Pablo Buenestado; Camacho, Mar

2013-01-01

Teacher education programs must offer pre-service students innovative technology-supported learning environments, guiding them in the revision of their preconceptions on literacy and technology. This present paper presents a case study that uses podcast to inquiry into future educators' views on technology and the digital age. Results show future…

7 CFR 1710.300 - General.

Code of Federal Regulations, 2014 CFR

2014-01-01

... board of directors and the manager to guide the system towards its financial goals. (b) A borrower must... in support of a loan application shall include: (1) The projected results of future actions planned... DSC; (5) Current and projected cash flows; (6) Projections of future borrowings and the associated...

7 CFR 1710.300 - General.

Code of Federal Regulations, 2012 CFR

2012-01-01

... forecast. The forecast should be used by the board of directors and the manager to guide the system towards... projected results of future actions planned by the borrower's board of directors; (2) The financial goals... type of large power loads, projections of future borrowings and the associated interest, projected...

7 CFR 1710.300 - General.

Code of Federal Regulations, 2013 CFR

2013-01-01

... forecast. The forecast should be used by the board of directors and the manager to guide the system towards... projected results of future actions planned by the borrower's board of directors; (2) The financial goals... type of large power loads, projections of future borrowings and the associated interest, projected...

Endobronchial ultrasonography using a guide sheath technique for diagnosis of peripheral pulmonary lesions

PubMed Central

Zhang, Lei; Wu, Hongxu; Wang, Guiqi

2017-01-01

Endobronchial ultrasonography using a guide sheath (EBUS-GS) is a novel method used for collecting peripheral pulmonary lesion (PPL) samples. EBUS-GS is performed by introducing a guide sheath-covered miniprobe into the target bronchus and then withdrawing the miniprobe after lesion detection, leaving the guide sheath in situ as a working channel for obtaining lesion samples. EBUS-GS can improve PPL diagnosis rates and be used for obtaining specimens for molecular analysis. In this review, we discuss the clinical applications of EBUS-GS, the factors that affect its diagnostic sensitivity, and potential complications. We also compare EBUS-GS with other available diagnostic techniques and discuss the strengths and limitations of this method. PMID:29063872

Training Cambodian Village Health Support Guides in Diabetes Prevention: Effects on Guides' Knowledge and Teaching Activities Over 6 Months.

PubMed

Wagner, Julie; Keuky, Lim; Fraser-King, Lorraine; Kuoch, Theanvy; Scully, Mary

2016-04-01

Type 2 diabetes is a pressing public health concern in Cambodia, a country with limited human resource capacity due to genocide. Cambodian village health support guides (Guides) promote health at the local level. This paper reports preliminary results of training Guides in diabetes prevention. The curriculum, called Eat, Walk, Sleep was delivered to Guides in Siem Reap province once over 3 h. Participants completed a pretest and posttest on diabetes knowledge. Guides were offered continuing education through Eat, Walk, Sleep resources and were encouraged to teach Eat, Walk, Sleep in their villages. For each of 6 months following their training, Guides completed a checklist regarding their activities. One hundred eighty-five Guides attended one of ten trainings. Knowledge scores increased significantly from pretest to posttest. During 6 months of follow-up, n = 159 Guides (85 %) completed at least one monthly checklist. Guides reported high rates of uptake and delivery of the Eat, Walk, Sleep curriculum and moderate rates of continuing education about diabetes. Diabetes prevention in Cambodia is nascent. Guides show excellent uptake and dissemination of the curriculum. Future research should examine effect of support for Guide activities and the effect of the curriculum on villager health behaviors, and ultimately, on rates of type 2 diabetes.

Communication: Fourier-transform infrared probing of remarkable quantities of gas trapped in cold homogeneously nucleated nanodroplets.

PubMed

Uras-Aytemiz, Nevin; Devlin, J Paul

2013-07-14

Studies of catalyzed all-vapor gas-hydrate formation on a sub-second timescale have been extended with a special focus on liquid-droplet compositions at the instant of hydrate crystallization. This focus has been enabled by inclusion of methanol in the all-vapor mixture. This slows droplet to gas-hydrate conversion near 200 K to a time scale suited for standard FTIR sampling. Such droplet data are sought as a guide to ongoing efforts to reduce the amount of guest catalyst required for instant formation of the gas hydrates. For the same reason, all-vapor sampling has also been extended to the generation of long-lived liquid droplets with reduced or no water content. Observations of single-solvent droplets show that surprising quantities of gas molecules are trapped during rapid droplet growth. For example, CO2 is trapped at levels near 50 mol. % in droplets of acetone, tetrahydrofuran, or trimethylene oxide formed under CO2 pressures of several Torr in a cold-chamber at 170 K. Less but significant amounts of gas are trapped at higher temperatures, or in methanol or water-methanol droplets. The droplet metastability appears to commonly lead to formation of bubbles larger than the original nanodroplets. Besides serving as a guide for the all-vapor gas-hydrate studies, the semiquantitative evidence of extensive trapping of gases is expected to have a role in future studies of atmospheric aerosols.

Communication: Fourier-transform infrared probing of remarkable quantities of gas trapped in cold homogeneously nucleated nanodroplets

NASA Astrophysics Data System (ADS)

Uras-Aytemiz, Nevin; Devlin, J. Paul

2013-07-01

Studies of catalyzed all-vapor gas-hydrate formation on a sub-second timescale have been extended with a special focus on liquid-droplet compositions at the instant of hydrate crystallization. This focus has been enabled by inclusion of methanol in the all-vapor mixture. This slows droplet to gas-hydrate conversion near 200 K to a time scale suited for standard FTIR sampling. Such droplet data are sought as a guide to ongoing efforts to reduce the amount of guest catalyst required for instant formation of the gas hydrates. For the same reason, all-vapor sampling has also been extended to the generation of long-lived liquid droplets with reduced or no water content. Observations of single-solvent droplets show that surprising quantities of gas molecules are trapped during rapid droplet growth. For example, CO2 is trapped at levels near 50 mol. % in droplets of acetone, tetrahydrofuran, or trimethylene oxide formed under CO2 pressures of several Torr in a cold-chamber at 170 K. Less but significant amounts of gas are trapped at higher temperatures, or in methanol or water-methanol droplets. The droplet metastability appears to commonly lead to formation of bubbles larger than the original nanodroplets. Besides serving as a guide for the all-vapor gas-hydrate studies, the semiquantitative evidence of extensive trapping of gases is expected to have a role in future studies of atmospheric aerosols.

Family Violence and Child Sexual Abuse Among South Asians in the US.

PubMed

Robertson, Hillary A; Chaudhary Nagaraj, Nitasha; Vyas, Amita N

2016-08-01

Family violence, including child sexual abuse (CSA), is a significant public health problem in the United States. It is particularly difficult to assess family violence and CSA among South Asians because it is often hidden due to cultural and familial stigma. A web-based survey was administered to a convenience sample (n = 368) of South Asian adults in the US. One-fourth (25.2 %) of the sample reported CSA; 13.8 % reported abuse involving exposure; 21.5 % reported abuse involving touching; 4.5 % reported attempted sexual intercourse; and 3.5 % reported forced sexual intercourse. Adjusted odds ratios found that participants who reported any relationship violence were significantly more likely to have experienced CSA (OR 2.28; 95 % CI 1.26-4.13); and suicide attempt was significantly associated with CSA (OR 3.96; 95 % CI 1.27-12.3). The findings presented in this formative study will assist in guiding future studies and interventions for South Asians in the United States.

Workflows and individual differences during visually guided routine tasks in a road traffic management control room.

PubMed

Starke, Sandra D; Baber, Chris; Cooke, Neil J; Howes, Andrew

2017-05-01

Road traffic control rooms rely on human operators to monitor and interact with information presented on multiple displays. Past studies have found inconsistent use of available visual information sources in such settings across different domains. In this study, we aimed to broaden the understanding of observer behaviour in control rooms by analysing a case study in road traffic control. We conducted a field study in a live road traffic control room where five operators responded to incidents while wearing a mobile eye tracker. Using qualitative and quantitative approaches, we investigated the operators' workflow using ergonomics methods and quantified visual information sampling. We found that individuals showed differing preferences for viewing modalities and weighting of task components, with a strong coupling between eye and head movement. For the quantitative analysis of the eye tracking data, we propose a number of metrics which may prove useful to compare visual sampling behaviour across domains in future. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

Brain Stimulation in Alzheimer's Disease.

PubMed

Chang, Chun-Hung; Lane, Hsien-Yuan; Lin, Chieh-Hsin

2018-01-01

Brain stimulation techniques can modulate cognitive functions in many neuropsychiatric diseases. Pilot studies have shown promising effects of brain stimulations on Alzheimer's disease (AD). Brain stimulations can be categorized into non-invasive brain stimulation (NIBS) and invasive brain stimulation (IBS). IBS includes deep brain stimulation (DBS), and invasive vagus nerve stimulation (VNS), whereas NIBS includes transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), electroconvulsive treatment (ECT), magnetic seizure therapy (MST), cranial electrostimulation (CES), and non-invasive VNS. We reviewed the cutting-edge research on these brain stimulation techniques and discussed their therapeutic effects on AD. Both IBS and NIBS may have potential to be developed as novel treatments for AD; however, mixed findings may result from different study designs, patients selection, population, or samples sizes. Therefore, the efficacy of NIBS and IBS in AD remains uncertain, and needs to be further investigated. Moreover, more standardized study designs with larger sample sizes and longitudinal follow-up are warranted for establishing a structural guide for future studies and clinical application.

Guided goal setting: effectiveness in a dietary and physical activity intervention with low-income adolescents.

PubMed

Shilts, Mical Kay; Horowitz, Marcel; Townsend, Marilyn S

2009-01-01

Determining the effectiveness of the guided goal setting strategy on changing adolescents' dietary and physical activity self-efficacy and behaviors. Adolescents were individually assigned to treatment (intervention with guided goal setting) or control conditions (intervention without guided goal setting) with data collected before and after the education intervention. Urban middle school in a low-income community in Central California. Ethnically diverse middle school students (n = 94, 55% male) who were participants of a USDA nutrition education program. Driven by the Social Cognitive Theory, the intervention targeted dietary and physical activity behaviors of adolescents. Dietary self-efficacy and behavior; physical activity self-efficacy and behavior; goal effort and spontaneous goal setting. ANCOVA and path analysis were performed using the full sample and a sub-sample informed by Locke's recommendations (accounting for goal effort and spontaneous goal setting). No significant differences were found between groups using the full sample. Using the sub-sample, greater gains in dietary behavior (p < .05), physical activity behavior (p < .05), and physical activity self-efficacy (p < .05) were made by treatment participants compared to control participants. Change in physical activity behaviors was mediated by self-efficacy. Accounting for goal effort and spontaneous goal setting, this study provides some evidence that the use of guided goal setting with adolescents may be a viable strategy to promote dietary and physical activity behavior change.

Methods for correcting tilt anisoplanatism in laser-guide-star-based multiconjugate adaptive optics.

PubMed

Ellerbroek, B L; Rigaut, F

2001-10-01

Multiconjugate adaptive optics (MCAO) is a technique for correcting turbulence-induced phase distortions in three dimensions instead of two, thereby greatly expanding the corrected field of view of an adaptive optics system. This is accomplished with use of multiple deformable mirrors conjugate to distinct ranges in the atmosphere, with actuator commands computed from wave-front sensor (WFS) measurements from multiple guide stars. Laser guide stars (LGSs) must be used (at least for the forseeable future) to achieve a useful degree of sky coverage in an astronomical MCAO system. Much as a single LGS cannot be used to measure overall wave-front tilt, a constellation of multiple LGSs at a common range cannot detect tilt anisoplanatism. This error alone will significantly degrade the performance of a MCAO system based on a single tilt-only natural guide star (NGS) and multiple tilt-removed LGSs at a common altitude. We present a heuristic, low-order model for the principal source of tilt anisoplanatism that suggests four possible approaches to eliminating this defect in LGS MCAO: (i) tip/tilt measurements from multiple NGS, (ii) a solution to the LGS tilt uncertainty problem, (iii) additional higher-order WFS measurements from a single NGS, or (iv) higher-order WFS measurements from both sodium and Rayleigh LGSs at different ranges. Sample numerical results for one particular MCAO system configuration indicate that approach (ii), if feasible, would provide the highest degree of tilt anisoplanatism compensation. Approaches (i) and (iv) also provide very useful levels of performance and do not require unrealistically low levels of WFS measurement noise. For a representative set of parameters for an 8-m telescope, the additional laser power required for approach (iv) is on the order of 2 W per Rayleigh LGS.

Financial strain and smoking cessation among men and women within a self-guided quit attempt.

PubMed

Reitzel, Lorraine R; Langdon, Kirsten J; Nguyen, Nga T; Zvolensky, Michael J

2015-08-01

Financial strain, defined as an unfavorable asset-to-needs ratio, has been associated with reduced odds of smoking cessation in the context of a structured clinical study providing cessation assistance. This study reports on a secondary data analysis that assessed the association of financial strain and biochemically-verified smoking abstinence within a structured clinical study of smokers making a self-guided cessation attempt. Participants (N=58; 65.5% men) were enrolled in a study about anxiety sensitivity and smoking cessation whereby they were instructed to initiate a self-guided quit attempt. Relations between financial strain and biochemically-verified smoking abstinence on the quit day and at Days 3, 7, 14, 28, and 90 post-quit were assessed using generalized estimating equations controlling for age, sex, race, education, partner status, pre-quit cigarettes smoked per day, and time. Associations between financial strain and abstinence in the whole sample were marginal (aOR=.94, 95% CI=.87-1.01, observations=293; p=.07). However, sex was a significant moderator: greater financial strain was associated with lower odds of abstinence for men (aOR=.90, 95% CI=.80-1.00, observations=201; p=.05), but not women (aOR=1.05, 95% CI=.91-1.21, observations=92; p=.48). Results indicated that financial strain was associated with lower odds of cessation among men undergoing a self-guided quit attempt in the context of a structured clinical study. These data suggest that financial strain may be an important socioeconomic determinant of smoking cessation and support its relevance for better understanding socioeconomic-based smoking-related health disparities. Future work may benefit by exploring sex-specific models of financial strain in the context of smoking cessation. Copyright © 2015 Elsevier Ltd. All rights reserved.

Financial Strain and Smoking Cessation among Men and Women within a Self-Guided Quit Attempt

PubMed Central

Reitzel, Lorraine R.; Langdon, Kirsten J.; Nguyen, Nga T.; Zvolensky, Michael J.

2015-01-01

Financial strain, defined as an unfavorable asset-to-needs ratio, has been associated with reduced odds of smoking cessation in the context of a structured clinical study providing cessation assistance. This study reports on a secondary data analysis that assessed the association of financial strain and biochemically-verified smoking abstinence within a structured clinical study of smokers making a self-guided cessation attempt. Participants (N=58; 65.5% men) were enrolled in a study about anxiety sensitivity and smoking cessation whereby they were instructed to initiate a self-guided quit attempt. Relations between financial strain and biochemically-verified smoking abstinence on the quit day and at Days 3, 7, 14, 28, and 90 post-quit were assessed using generalized estimating equations controlling for age, sex, race, education, partner status, pre-quit cigarettes smoked per day, and time. Associations between financial strain and abstinence in the whole sample were marginal (aOR=.94, 95% CI=.87-1.01, observations=293; p=.07). However, sex was a significant moderator: greater financial strain was associated with lower odds of abstinence for men (aOR=.90, 95% CI= .80-1.00, observations=201; p=.05), but not women (aOR=1.05, 95% CI= .91-1.21, observations=92; p=.48). Results indicated that financial strain was associated with lower odds of cessation among men undergoing a self-guided quit attempt in the context of a structured clinical study. These data suggest financial strain may be an important socioeconomic determinant of smoking cessation and support its relevance for better understanding socioeconomic-based smoking-related health disparities. Future work may benefit by exploring sex-specific models of financial strain in the context of smoking cessation. PMID:25879712

N-acetylcysteine in a Double-Blind Randomized Placebo-Controlled Trial: Toward Biomarker-Guided Treatment in Early Psychosis

PubMed Central

Conus, Philippe; Seidman, Larry J; Fournier, Margot; Xin, Lijing; Cleusix, Martine; Baumann, Philipp S; Ferrari, Carina; Cousins, Ann; Alameda, Luis; Gholam-Rezaee, Mehdi; Golay, Philippe; Jenni, Raoul; Woo, T -U Wilson; Keshavan, Matcheri S; Eap, Chin B; Wojcik, Joanne; Cuenod, Michel; Buclin, Thierry; Gruetter, Rolf

2018-01-01

Abstract Biomarker-guided treatments are needed in psychiatry, and previous data suggest oxidative stress may be a target in schizophrenia. A previous add-on trial with the antioxidant N-acetylcysteine (NAC) led to negative symptom reductions in chronic patients. We aim to study NAC’s impact on symptoms and neurocognition in early psychosis (EP) and to explore whether glutathione (GSH)/redox markers could represent valid biomarkers to guide treatment. In a double-blind, randomized, placebo-controlled trial in 63 EP patients, we assessed the effect of NAC supplementation (2700 mg/day, 6 months) on PANSS, neurocognition, and redox markers (brain GSH [GSHmPFC], blood cells GSH levels [GSHBC], GSH peroxidase activity [GPxBC]). No changes in negative or positive symptoms or functional outcome were observed with NAC, but significant improvements were found in favor of NAC on neurocognition (processing speed). NAC also led to increases of GSHmPFC by 23% (P = .005) and GSHBC by 19% (P = .05). In patients with high-baseline GPxBC compared to low-baseline GPxBC, subgroup explorations revealed a link between changes of positive symptoms and changes of redox status with NAC. In conclusion, NAC supplementation in a limited sample of EP patients did not improve negative symptoms, which were at modest baseline levels. However, NAC led to some neurocognitive improvements and an increase in brain GSH levels, indicating good target engagement. Blood GPx activity, a redox peripheral index associated with brain GSH levels, could help identify a subgroup of patients who improve their positive symptoms with NAC. Thus, future trials with antioxidants in EP should consider biomarker-guided treatment. PMID:29462456

Pathways between self-esteem and depression in couples.

PubMed

Johnson, Matthew D; Galambos, Nancy L; Finn, Christine; Neyer, Franz J; Horne, Rebecca M

2017-04-01

Guided by concepts from a relational developmental perspective, this study examined intra- and interpersonal associations between self-esteem and depressive symptoms in a sample of 1,407 couples surveyed annually across 6 years in the Panel Analysis of Intimate Relations and Family Dynamics (pairfam) study. Autoregressive cross-lagged model results demonstrated that self-esteem predicted future depressive symptoms for male partners at all times, replicating the vulnerability model for men (low self-esteem is a risk factor for future depression). Additionally, a cross-partner association emerged between symptoms of depression: Higher depressive symptoms in one partner were associated with higher levels of depression in the other partner one year later. Finally, supportive dyadic coping, the support that partners reported providing to one another in times of stress, was tested as a potential interpersonal mediator of pathways between self-esteem and depression. Female partners' higher initial levels of self-esteem predicted male partners' subsequent reports of increased supportive dyadic coping, which, in turn, predicted higher self-esteem and fewer symptoms of depression among female partners in the future. Male partners' initially higher symptoms of depression predicted less frequent supportive dyadic coping subsequently reported by female partners, which was associated with increased feelings of depression in the future. Couple relations represent an important contextual factor that may be implicated in the developmental pathways connecting self-esteem and symptoms of depression. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Forming Attitudes that Predict Future Behavior: A Meta-Analysis of the Attitude-Behavior Relation

ERIC Educational Resources Information Center

Glasman, Laura R.; Albarracin, Dolores

2006-01-01

A meta-analysis (k of conditions = 128; N = 4,598) examined the influence of factors present at the time an attitude is formed on the degree to which this attitude guides future behavior. The findings indicated that attitudes correlated with a future behavior more strongly when they were easy to recall (accessible) and stable over time. Because of…

Ultrasound-Guided Treatment of Peripheral Nerve Pathology.

PubMed

Dettori, Nathan; Choudur, Hema; Chhabra, Avneesh

2018-07-01

High-resolution ultrasound serves as a fast, accessible, reliable, and radiation-free tool for anatomical and dynamic evaluation of various peripheral nerves. It can be used not only to identify and diagnose peripheral nerve and perineural pathology accurately but also to guide various nerve and perineural interventions. We describe the normal and pathologic appearances of peripheral nerves, the pathologies commonly affecting the individual peripheral nerves, and the current ultrasound-guided peripheral nerve interventions and techniques. Future directions are also highlighted. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Smokeless Tobacco Use in the United States Military: A Systematic Review

PubMed Central

Hunt, Yvonne M.; Augustson, Erik

2012-01-01

Introduction: Smokeless tobacco (ST) use represents an important target for intervention in the U.S. military population because it impairs “military readiness” and harms the health of the military. This paper aims to provide a systematic review of ST studies conducted in the U.S. military population in order to assess the content of existing ST research in this population, provide estimates of prevalence and clinically relevant use patterns, and discuss how these findings might be used to guide future ST research among this population. Methods: We reviewed articles published through December 2010 using PubMed and PsycINFO databases, Google Scholar, and any relevant articles’ reference lists. Inclusion criteria included focus on a U.S. military sample, English language, measured tobacco use, and ST prevalence was reported or could be calculated. To the extent possible, each article was coded for demographics, socioeconomic status, prevalence, amount, frequency, and length of use, and quit intentions/attempts. Results: Thirty-nine articles met criteria for inclusion. Less than half focused primarily on ST use among military personnel. The remaining studies measured ST use in the context of other behaviors. Findings related to clinically relevant behaviors included a need for more cohort and intervention studies, a better understanding of ST use in combination with cigarettes (i.e., concurrent use), and identifying risk factors for ST initiation and use. Discussion: ST use is prevalent among military personnel, as is concurrent use of cigarettes and ST. We provide a number of recommendations to guide future research in this important, yet understudied, area. PMID:22123789

Detecting seasonal and cyclical trends in agricultural runoff water quality-hypothesis tests and block bootstrap power analysis.

PubMed

Uddameri, Venkatesh; Singaraju, Sreeram; Hernandez, E Annette

2018-02-21

Seasonal and cyclic trends in nutrient concentrations at four agricultural drainage ditches were assessed using a dataset generated from a multivariate, multiscale, multiyear water quality monitoring effort in the agriculturally dominant Lower Rio Grande Valley (LRGV) River Watershed in South Texas. An innovative bootstrap sampling-based power analysis procedure was developed to evaluate the ability of Mann-Whitney and Noether tests to discern trends and to guide future monitoring efforts. The Mann-Whitney U test was able to detect significant changes between summer and winter nutrient concentrations at sites with lower depths and unimpeded flows. Pollutant dilution, non-agricultural loadings, and in-channel flow structures (weirs) masked the effects of seasonality. The detection of cyclical trends using the Noether test was highest in the presence of vegetation mainly for total phosphorus and oxidized nitrogen (nitrite + nitrate) compared to dissolved phosphorus and reduced nitrogen (total Kjeldahl nitrogen-TKN). Prospective power analysis indicated that while increased monitoring can lead to higher statistical power, the effect size (i.e., the total number of trend sequences within a time-series) had a greater influence on the Noether test. Both Mann-Whitney and Noether tests provide complementary information on seasonal and cyclic behavior of pollutant concentrations and are affected by different processes. The results from these statistical tests when evaluated in the context of flow, vegetation, and in-channel hydraulic alterations can help guide future data collection and monitoring efforts. The study highlights the need for long-term monitoring of agricultural drainage ditches to properly discern seasonal and cyclical trends.

Columbia County Kindergarten Center Environmental Study Area Guide.

ERIC Educational Resources Information Center

Florida State Dept. of Education, Tallahassee. Office of Environment Education.

The guide lists seven program objectives and 15 activities guides for meeting the objectives. Included in each activity is an introduction, outdoor activity, classroom activity, and evaluation. Sample activities are: Animals Use Natural Materials to Provide Food and Shelter, Differences in Soil, Decomposition, Man-made or Natural Objects, Food…

Agriculture: Horticulture. Secondary Schools. Curriculum Guide.

ERIC Educational Resources Information Center

Trust Territory of the Pacific Islands Dept. of Education, Saipan.

This agricultural curriculum guide on horticulture for secondary students is one of six developed for inservice teachers at Marianas High School in Saipan. The guide provides the rationale, description, goals, and objectives of the program; the program of studies and performance objectives by levels; samples of lesson plans for effective delivery…

Construction: Masonry. Secondary Schools. Curriculum Guide.

ERIC Educational Resources Information Center

Trust Territory of the Pacific Islands Dept. of Education, Saipan.

This construction curriculum guide on masonry for secondary students is one of six developed for inservice teachers at Marianas High School in Saipan. The guide provides the rationale, description, goals, and objectives of the program; the program of studies and performance objectives by levels; samples of lesson plans for effective delivery of…

Secondary Social Studies: Alaska Curriculum Guide. Second Edition.

ERIC Educational Resources Information Center

Alaska State Dept. of Education, Juneau. Office of Curriculum Services.

A secondary social studies model curriculum guide for Alaska is presented. The body of the guide lists topics/concepts, learning outcomes/objectives, and sample learning activities in a 3 column format. The first column, topics/concepts, describes the content area, defining the subject broadly and listing subconcepts or associated vocabulary. The…

Electricity: Residential Wiring. Secondary Schools. Curriculum Guide.

ERIC Educational Resources Information Center

Trust Territory of the Pacific Islands Dept. of Education, Saipan.

This curriculum guide on residential wiring for secondary students is one of six developed for inservice teachers at Marianas High School in Saipan. The guide provides the rationale, description, goals, and objectives of the program; the program of studies and performance objectives by levels; samples of lesson plans for effective delivery of…

Flight Instructor: Airplane. Written Test Guide.

ERIC Educational Resources Information Center

Federal Aviation Administration (DOT), Washington, DC. Flight Standards Service.

The Flight Standards Service of the Federal Aviation Administration developed the guide to assist applicants who are preparing for the Flight Instructor Certificate with Airplane Rating. The guide contains comprehensive study outlines and a list of recommended study materials and tells how to obtain those publications. It also includes sample test…

Ion guiding in macro-size insulating capillaries: straight, tapered, and curved shapes

NASA Astrophysics Data System (ADS)

Kojima, Takao M.

2018-02-01

When keV energy ions are injected into a tilted insulating capillary, a certain fraction of the injected ions are transported through the tilt angle of the capillary. This ion guiding phenomenon is considered to be caused by a self-organizing charge distribution, where the inner wall of the capillary becomes charged by initial incoming ions. The charge distribution, which is formed, can guide following ions toward the exit of the capillary. Since the initial discovery of this effect, studies of ion guiding by insulating capillaries have been extended to various materials, and different sizes and shapes of capillaries. In recent years, some investigations of the guiding effect of macro-size curved capillaries have also been reported. In this review, relevant studies in a history of ion guiding in curved capillaries are discussed and future directions in this field are considered.

21st Century Readers' Aids: Past History and Future Directions

ERIC Educational Resources Information Center

Smith, Michael M.

2008-01-01

This article provides a brief history of the development of library subject guides (often referred to as pathfinders) from the late 1800s to the present. During this period, subject guides have changed both their focus and format. The needs of academic institutions at the turn of the 20th century were very different than they are today, and…

A Manual for Trainers of Small Scale Beekeeping Development Workers.

ERIC Educational Resources Information Center

Gentry, Curtis; And Others

This manual is intended to serve as a guide for those who are helping future Peace Corps Volunteers to acquire basic beekeeping skills. Included in the guide are lesson outlines and handouts for use in each of the 52 sessions of the course. Representative topics discussed in the individual sessions are family live-in, training site investigation,…

Making Changes: A Futures-Oriented Course in Inventive Problem Solving. Teacher's Guide.

ERIC Educational Resources Information Center

Thomas, John W.

This 1981 guide is designed to be used with a workbook offering students opportunities to engage in creative problem solving. The book contains four units with 23 lessons. Unit 1 addresses problem solving and contains nine lessons: (1) "New and Different Thinking"; (2) "Open and Closed Problems"; (3) "Stating a Problem"; (4) "Defining a Problem";…

Keyboarding and Computer Application. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This curriculum guide is designed to prepare students in grades 6-10 to work in the world of the future. The 8-day course provides exploratory, hands-on learning activities and information that can enhance the education of students of all types in an integrated curriculum that provides practical applications of academic skills. The guide contains…

Guiding Future Research on the Community College Transfer Function: Summary of a National Seminar (Washington, D.C., September 21-22, 1992).

ERIC Educational Resources Information Center

Ludwig, Meredith J.; Palmer, James C.

1993-01-01

In September 1992, a small group of experienced researchers met to identify areas of research and specific research hypotheses to guide further inquiry into transfer. Specifically, participants examined transfer as it relates to institutional mission, institutional organization, and access to education and identified various premises upon which…

Teaching Strategies for Improving Algebra Knowledge in Middle and High School Students. Educator's Practice Guide. What Works Clearinghouse.™ NCEE 2015-4010

ERIC Educational Resources Information Center

Star, Jon R.; Foegen, Anne; Larson, Matthew R.; McCallum, William G.; Porath, Jane; Zbiek, Rose Mary; Caronongan, Pia; Furgeson, Joshua,; Keating, Betsy; Lyskawa, Julia

2015-01-01

Mastering algebra is important for future math and postsecondary success. Educators will find practical recommendations for how to improve algebra instruction in the What Works Clearinghouse (WWC) practice guide, "Teaching Strategies for Improving Algebra Knowledge in Middle and High School Students". The methods and examples included in…

17 CFR 30.4 - Registration required.

Code of Federal Regulations, 2010 CFR

2010-04-01

... foreign options customers. (d) To solicit or enter into an agreement to direct, or to guide such customer... Section 30.4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION FOREIGN FUTURES AND FOREIGN OPTIONS TRANSACTIONS § 30.4 Registration required. Except as provided in § 30.5 of this part, it...

Discerning the Future of Early Childhood Intervention.

ERIC Educational Resources Information Center

Zigler, Edward; Berman, Winnie

1983-01-01

Examines the recent history of early childhood intervention efforts; discusses principles that guided the formation of intervention programs in the 1960s and 1970s; describes the Head Start program and lessons learned from its development; considers issues in evaluating intervention programs; and presents suggestions for future directions in early…

A Guide to Personal, Business and Social Forecasting and Survival.

ERIC Educational Resources Information Center

Loye, David

1983-01-01

By thinking about and trying to predict the future, we force ourselves to articulate our feelings and thoughts about that future. A technique using intuitive and logical thinking based on right brain-left brain differences is proposed to aid in decision making by both groups and individuals. (Author/IS)

77 FR 35917 - Medicare Program; Medicare Secondary Payer and “Future Medicals”

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-15

... injured individual. We are interested in whether this type of approach is useful in guiding a determination as to whether future medical care will be required and if other approaches are available. Chronic... limitation, including asthma and chronic bronchitis; cancer, diabetes; quadriplegia; and nephrogenic systemic...

Population, Education, and Children's Futures. Fastback 150.

ERIC Educational Resources Information Center

Bjork, Robert M.; Fraser, Stewart E.

This monograph discusses world population problems, examines the underlying concepts and issues in population education, and looks at the future. The monograph begins by describing an attempt at population education in a village of India. Eight guiding concepts that are considered to be essential for population educators are then discussed. These…

The Future of Women's Athletics: Entertainment or Education?

ERIC Educational Resources Information Center

Park, Roberta J.

A well-rounded program of extramural opportunities for females which provides experience between the intramural model and the existing male intercollegiate models is presently nonexistent. Five possible alternatives to guide the future of athletics are suggested: (a) women could demand access to the existing model of male athletics; (b) women…

Characterization of C/Enhanced SiC Composite During Creep-Rupture Tests Using an Ultrasonic Guided Wave Scan System

NASA Technical Reports Server (NTRS)

Roth, Don J.; Verrilli, Michael J.; Martin, Richard E.; Cosgriff, Laura M.

2004-01-01

An ultrasonic guided wave scan system was used to nondestructively monitor damage over time and position in a C/enhanced SiC sample that was creep tested to failure at 1200 C in air at a stress of 69 MPa (10 ksi). The use of the guided wave scan system for mapping evolving oxidation profiles (via porosity gradients resulting from oxidation) along the sample length and predicting failure location was explored. The creep-rupture tests were interrupted for ultrasonic evaluation every two hours until failure at approx. 17.5 cumulative hours.

Exploring the Moon: A Teacher's Guide with Activities for Earth and Space Sciences.

ERIC Educational Resources Information Center

National Aeronautics and Space Administration, Washington, DC.

These materials have been designed for use with the upper elementary through high school levels especially, but not exclusively, with the Lunar Sample Disk. This book contains: information on the Lunar Sample Disk, a curriculum content matrix, a teacher's guide, Moon ABCs fact sheet, rock ABCs fact sheet, Progress in Lunar Science chart, 17…

Endoscopic Management of Pancreatic Fluid Collections in Children.

PubMed

Nabi, Zaheer; Talukdar, Rupjyoti; Reddy, D Nageshwar

2017-07-15

The incidence of acute pancreatitis in children has increased over the last few decades. The development of pancreatic fluid collection is not uncommon after severe acute pancreatitis, although its natural course in children and adolescents is poorly understood. Asymptomatic fluid collections can be safely observed without any intervention. However, the presence of clinically significant symptoms warrants the drainage of these fluid collections. Endoscopic management of pancreatic fluid collection is safe and effective in adults. The use of endoscopic ultrasound (EUS)-guided procedure has improved the efficacy and safety of drainage of pancreatic fluid collections, which have not been well studied in pediatric populations, barring a scant volume of small case series. Excellent results of EUS-guided drainage in adult patients also need to be verified in children and adolescents. Endoprostheses used to drain pancreatic fluid collections include plastic and metal stents. Metal stents have wider lumens and become clogged less often than plastic stents. Fully covered metal stents specifically designed for pancreatic fluid collection are available, and initial studies have shown encouraging results in adult patients. The future of endoscopic management of pancreatic fluid collection in children appears promising. Prospective studies with larger sample sizes are required to establish their definitive role in the pediatric age group.

Application of tolerance limits to the characterization of image registration performance.

PubMed

Fedorov, Andriy; Wells, William M; Kikinis, Ron; Tempany, Clare M; Vangel, Mark G

2014-07-01

Deformable image registration is used increasingly in image-guided interventions and other applications. However, validation and characterization of registration performance remain areas that require further study. We propose an analysis methodology for deriving tolerance limits on the initial conditions for deformable registration that reliably lead to a successful registration. This approach results in a concise summary of the probability of registration failure, while accounting for the variability in the test data. The (β, γ) tolerance limit can be interpreted as a value of the input parameter that leads to successful registration outcome in at least 100β% of cases with the 100γ% confidence. The utility of the methodology is illustrated by summarizing the performance of a deformable registration algorithm evaluated in three different experimental setups of increasing complexity. Our examples are based on clinical data collected during MRI-guided prostate biopsy registered using publicly available deformable registration tool. The results indicate that the proposed methodology can be used to generate concise graphical summaries of the experiments, as well as a probabilistic estimate of the registration outcome for a future sample. Its use may facilitate improved objective assessment, comparison and retrospective stress-testing of deformable.

Structure guided GANs

NASA Astrophysics Data System (ADS)

Cao, Feidao; Zhao, Huaici; Liu, Pengfei

2017-11-01

Generative adversarial networks (GANs) has achieved success in many fields. However, there are some samples generated by many GAN-based works, whose structure is ambiguous. In this work, we propose Structure Guided GANs that introduce structural similar into GANs to overcome the problem. In order to achieve our goal, we introduce an encoder and a decoder into a generator to design a new generator and take real samples as part of the input of a generator. And we modify the loss function of the generator accordingly. By comparison with WGAN, experimental results show that our proposed method overcomes largely sample structure ambiguous and can generate higher quality samples.

Validity of peer grading using Calibrated Peer Review in a guided-inquiry, conceptual physics course

NASA Astrophysics Data System (ADS)

Price, Edward; Goldberg, Fred; Robinson, Steve; McKean, Michael

2016-12-01

Constructing and evaluating explanations are important science practices, but in large classes it can be difficult to effectively engage students in these practices and provide feedback. Peer review and grading are scalable instructional approaches that address these concerns, but which raise questions about the validity of the peer grading process. Calibrated Peer Review (CPR) is a web-based system that scaffolds peer evaluation through a "calibration" process where students evaluate sample responses and receive feedback on their evaluations before evaluating their peers. Guided by an activity theory framework, we developed, implemented, and evaluated CPR-based tasks in guided-inquiry, conceptual physics courses for future teachers and general education students. The tasks were developed through iterative testing and revision. Effective tasks had specific and directed prompts and evaluation instructions. Using these tasks, over 350 students at three universities constructed explanations or analyzed physical phenomena, and evaluated their peers' work. By independently assessing students' responses, we evaluated the CPR calibration process and compared students' peer reviews with expert evaluations. On the tasks analyzed, peer scores were equivalent to our independent evaluations. On a written explanation item included on the final exam, students in the courses using CPR outperformed students in similar courses using traditional writing assignments without a peer evaluation element. Our research demonstrates that CPR can be an effective way to explicitly include the science practices of constructing and evaluating explanations into large classes without placing a significant burden on the instructor.

WE-EF-BRD-01: Past, Present and Future: MRI-Guided Radiotherapy From 2005 to 2025

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lagendijk, J.

MRI-guided treatment is a growing area of medicine, particularly in radiotherapy and surgery. The exquisite soft tissue anatomic contrast offered by MRI, along with functional imaging, makes the use of MRI during therapeutic procedures very attractive. Challenging the utility of MRI in the therapy room are many issues including the physics of MRI and the impact on the environment and therapeutic instruments, the impact of the room and instruments on the MRI; safety, space, design and cost. In this session, the applications and challenges of MRI-guided treatment will be described. The session format is: Past, present and future: MRI-guided radiotherapymore » from 2005 to 2025: Jan Lagendijk Battling Maxwell’s equations: Physics challenges and solutions for hybrid MRI systems: Paul Keall I want it now!: Advances in MRI acquisition, reconstruction and the use of priors to enable fast anatomic and physiologic imaging to inform guidance and adaptation decisions: Yanle Hu MR in the OR: The growth and applications of MRI for interventional radiology and surgery: Rebecca Fahrig Learning Objectives: To understand the history and trajectory of MRI-guided radiotherapy To understand the challenges of integrating MR imaging systems with linear accelerators To understand the latest in fast MRI methods to enable the visualisation of anatomy and physiology on radiotherapy treatment timescales To understand the growing role and challenges of MRI for image-guided surgical procedures My disclosures are publicly available and updated at: http://sydney.edu.au/medicine/radiation-physics/about-us/disclosures.php.« less

Four faint T dwarfs from the UKIRT Infrared Deep Sky Survey (UKIDSS) Southern Stripe

NASA Astrophysics Data System (ADS)

Chiu, Kuenley; Liu, Michael C.; Jiang, Linhua; Allers, Katelyn N.; Stark, Daniel P.; Bunker, Andrew; Fan, Xiaohui; Glazebrook, Karl; Dupuy, Trent J.

2008-03-01

We present the optical and near-infrared photometry and spectroscopy of four faint T dwarfs newly discovered from the UKIDSS first data release. The sample, drawn from an imaged area of ~136 deg2 to a depth of Y = 19.9 (5σ, Vega), is located in the Sloan Digital Sky Survey (SDSS) Southern Equatorial Stripe, a region of significant future deep imaging potential. We detail the selection and followup of these objects, three of which are spectroscopically confirmed brown dwarfs ranging from type T2.5 to T7.5, and one is photometrically identified as early T. Their magnitudes range from Y = 19.01 to 19.88 with derived distances from 34 to 98 pc, making these among the coldest and faintest brown dwarfs known. The T7.5 dwarf appears to be single based on 0.05-arcsec images from Keck laser guide star adaptive optics. The sample brings the total number of T dwarfs found or confirmed by UKIDSS data in this region to nine, and we discuss the projected numbers of dwarfs in the future survey data. We estimate that ~240 early and late T dwarfs are discoverable in the UKIDSS Large Area Survey (LAS) data, falling significantly short of published model projections and suggesting that initial mass functions and/or birth rates may be at the low end of possible models. Thus, deeper optical data have good potential to exploit the UKIDSS survey depth more fully, but may still find the potential Y dwarf sample to be extremely rare.

Le Temps, des sucres [Sugaring-Off Time]. Teacher's Guide.

ERIC Educational Resources Information Center

Ullmann, Rebecca; And Others

A resource kit for the teaching of listening comprehension in French at the beginning elementary level is represented by a teacher's guide and a handbook entitled "The Maple Sugar Industry." The guide offers sample activities and lesson plans, as well as a complete procedure for conducting a listening comprehension test. Instructions are given for…

Nutrition and Meal Planning in Child-Care Programs: A Practical Guide.

ERIC Educational Resources Information Center

Edelstein, Sari

Designed to assist child care center managers in planning nutritious meals for children in centers or licensed home day care programs, this guide presents information on the nutritional requirements of infants and children, sample menus for child care centers, and resources for further information. The first part of the guide details the…

A Catalog of Tasks, Performance Objectives, Performance Guides, Tools, and Equipment, Homemaker Human Development.

ERIC Educational Resources Information Center

Watkins, Betty; And Others

This catalog was designed to provide performance objectives and performance guides associated with current occupational information relating to the job of homemaker. The performance objectives and guides were developed following a literature review and a survey of random samples of homemakers in the five participating states (Alabama, Florida,…

The Effect of Guided Self-Reflection on Teachers' Technology Use

ERIC Educational Resources Information Center

Farber, Susan

2010-01-01

The purpose of this study was to pilot an instructional planning tool grounded in guided self-reflection on the instructional planning practices and instructional behaviors of a small sample of teachers. I designed the instructional planning tool, which was named the Informed Technology Integration Guide (ITIG). Participants used the instructional…

Home Economics: Foods and Nutrition. Secondary Schools. Curriculum Guide.

ERIC Educational Resources Information Center

Trust Territory of the Pacific Islands Dept. of Education, Saipan.

This home economics curriculum guide on foods and nutrition for secondary students is one of six developed for inservice teachers at Marianas High School in Saipan. The guide provides the rationale, description, goals, and objectives of the program; the program of studies and performance objectives by levels; samples of lesson plans for effective…

Principles of effective USA federal fire management plans

USGS Publications Warehouse

Meyer, Marc D.; Roberts, Susan L.; Wills, Robin; Brooks, Matthew L.; Winford, Eric M.

2015-01-01

Federal fire management plans are essential implementation guides for the management of wildland fire on federal lands. Recent changes in federal fire policy implementation guidance and fire science information suggest the need for substantial changes in federal fire management plans of the United States. Federal land management agencies are also undergoing land management planning efforts that will initiate revision of fire management plans across the country. Using the southern Sierra Nevada as a case study, we briefly describe the underlying framework of fire management plans, assess their consistency with guiding principles based on current science information and federal policy guidance, and provide recommendations for the development of future fire management plans. Based on our review, we recommend that future fire management plans be: (1) consistent and compatible, (2) collaborative, (3) clear and comprehensive, (4) spatially and temporally scalable, (5) informed by the best available science, and (6) flexible and adaptive. In addition, we identify and describe several strategic guides or “tools” that can enhance these core principles and benefit future fire management plans in the following areas: planning and prioritization, science integration, climate change adaptation, partnerships, monitoring, education and communication, and applied fire management. These principles and tools are essential to successfully realize fire management goals and objectives in a rapidly changing world.

Automated real-time needle-guide tracking for fast 3-T MR-guided transrectal prostate biopsy: a feasibility study.

PubMed

Zamecnik, Patrik; Schouten, Martijn G; Krafft, Axel J; Maier, Florian; Schlemmer, Heinz-Peter; Barentsz, Jelle O; Bock, Michael; Fütterer, Jurgen J

2014-12-01

To assess the feasibility of automatic needle-guide tracking by using a real-time phase-only cross correlation ( POCC phase-only cross correlation ) algorithm-based sequence for transrectal 3-T in-bore magnetic resonance (MR)-guided prostate biopsies. This study was approved by the ethics review board, and written informed consent was obtained from all patients. Eleven patients with a prostate-specific antigen level of at least 4 ng/mL (4 μg/L) and at least one transrectal ultrasonography-guided biopsy session with negative findings were enrolled. Regions suspicious for cancer were identified on 3-T multiparametric MR images. During a subsequent MR-guided biopsy, the regions suspicious for cancer were reidentified and targeted by using the POCC phase-only cross correlation -based tracking sequence. Besides testing a general technical feasibility of the biopsy procedure by using the POCC phase-only cross correlation -based tracking sequence, the procedure times were measured, and a pathologic analysis of the biopsy cores was performed. Thirty-eight core samples were obtained from 25 regions suspicious for cancer. It was technically feasible to perform the POCC phase-only cross correlation -based biopsies in all regions suspicious for cancer in each patient, with adequate biopsy samples obtained with each biopsy attempt. The median size of the region suspicious for cancer was 8 mm (range, 4-13 mm). In each region suspicious for cancer (median number per patient, two; range, 1-4), a median of one core sample per region was obtained (range, 1-3). The median time for guidance per target was 1.5 minutes (range, 0.7-5 minutes). Nineteen of 38 core biopsy samples contained cancer. This study shows that it is feasible to perform transrectal 3-T MR-guided biopsies by using a POCC phase-only cross correlation algorithm-based real-time tracking sequence. © RSNA, 2014.

Magnetization reversal in magnetic dot arrays: Nearest-neighbor interactions and global configurational anisotropy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Van de Wiele, Ben; Fin, Samuele; Pancaldi, Matteo

2016-05-28

Various proposals for future magnetic memories, data processing devices, and sensors rely on a precise control of the magnetization ground state and magnetization reversal process in periodically patterned media. In finite dot arrays, such control is hampered by the magnetostatic interactions between the nanomagnets, leading to the non-uniform magnetization state distributions throughout the sample while reversing. In this paper, we evidence how during reversal typical geometric arrangements of dots in an identical magnetization state appear that originate in the dominance of either Global Configurational Anisotropy or Nearest-Neighbor Magnetostatic interactions, which depends on the fields at which the magnetization reversal setsmore » in. Based on our findings, we propose design rules to obtain the uniform magnetization state distributions throughout the array, and also suggest future research directions to achieve non-uniform state distributions of interest, e.g., when aiming at guiding spin wave edge-modes through dot arrays. Our insights are based on the Magneto-Optical Kerr Effect and Magnetic Force Microscopy measurements as well as the extensive micromagnetic simulations.« less

Attitudes towards collaboration and servant leadership among nurses, physicians and residents.

PubMed

Garber, Jeannie Scruggs; Madigan, Elizabeth A; Click, Elizabeth R; Fitzpatrick, Joyce J

2009-07-01

A descriptive, comparative study was conducted to examine the attitudes of nurses, physicians and residents towards collaboration and to assess their self-perception of servant leadership characteristics. The Jefferson Scale of Attitudes toward Physician-Nurse Collaboration and the Barbuto-Wheeler Servant Leadership Questionnaire were utilized for data collection. Registered nurses (RNs) (n = 2,660), physicians (n = 447) and residents (n = 171) in a Southeastern United States health system were surveyed via the intranet; there were 497 responses for analysis. The response rate should be considered and generalizations made with caution regarding the study results. RN scores were higher for both total scores and subscales as compared to physician/resident groups for collaboration and servant leadership. There was a weak positive correlation between collaboration and servant leadership in the RN group and no significant correlation between the variables in the physician/resident group. Findings from this study have implications for nursing and physician education and practice and may serve as a framework for future studies. Representative samples are needed to gain further insight and to guide future research.

Sleep Disturbances in Adolescents with ADHD: A Systematic Review and Framework for Future Research

PubMed Central

Lunsford-Avery, Jessica R.; Krystal, Andrew D.; Kollins, Scott H.

2016-01-01

Background Biological mechanisms underlying symptom and prognostic heterogeneity in Attention-Deficit/Hyperactivity Disorder (ADHD) are unclear. Sleep impacts neurocognition and daytime functioning and is disrupted in ADHD, yet little is known about sleep in ADHD during adolescence, a period characterized by alterations in sleep, brain structure, and environmental demands as well as diverging ADHD trajectories. Methods A systematic review identified studies published prior to August 2016 assessing sleep in adolescents (aged 10–19 years) with ADHD or participating in population-based studies measuring ADHD symptoms. Results Twenty-five studies were identified (19 subjective report, 6 using actigraphy/polysomnography). Findings are mixed but overall suggest associations between sleep disturbances and 1) ADHD symptoms in the population and 2) poorer clinical, neurocognitive, and functional outcomes among adolescents with ADHD. Common limitations of studies included small or non-representative samples, non-standardized sleep measures, and cross-sectional methodology. Conclusions Current data on sleep in adolescent ADHD are sparse and limited by methodological concerns. Future studies are critical for clarifying a potential role of sleep in contributing to heterogeneity of ADHD presentation and prognosis. Potential mechanisms by which sleep disturbances during adolescence may contribute to worsened symptom severity and persistence of ADHD into adulthood and an agenda to guide future research are discussed. PMID:27969004

Families and Futures 2000. A Resource for Planning Comprehensive Home and Family Life Education Programs. Working Papers.

ERIC Educational Resources Information Center

Washington Office of the State Superintendent of Public Instruction, Olympia.

This curriculum guide is the first step in a total home and family life curriculum revision in the state of Washington aimed at helping students solve problems and study issues that have an impact on home and family life. The guide contains two model, nonsequential, comprehensive courses that may be adopted or adapted by school districts. The…

Project EFFECT. Energy for the Future: Education, Conservation, Training. Curriculum Guides for the Training of Energy Extension Agents. A Working Paper, Section II: Technical Training.

ERIC Educational Resources Information Center

Indiana Univ., South Bend. Center for Energy Conservation.

This second of four sections in a curriculum guide for training energy extension agents contains general introductory materials, an overview of the total curriculum, and eight modules: Alternative Energy Sources (Solar and Wood), Basic Graphics and Blueprint Reading, Building Materials, Electricity, Introduction to Cooling Systems, Introduction to…

75 FR 22674 - U.S. Department of State Advisory Committee on Private International Law Study Group Notice of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-29

... Intellectual Property (IP) The Department of State, Office of the Legal Adviser, Private International Law and... rights in intellectual property, as well as possible future work in UNCITRAL on an IP licensing guide.../689), as well as the draft text of the IP supplement to the Guide (A/CN.9/700 and Add. 1-7) that will...

Environmental Scanning for Occupational Education. A Facilitator's Guide. A Model for Environmental Scanning to Systematically Assess Future Occupational Education and Training Needs of a Michigan Community College Service Area.

ERIC Educational Resources Information Center

Kellogg Foundation, Battle Creek, MI.

This manual is designed to facilitate the planning and implementation of an environmental scanning project in Michigan's community colleges. (Environmental scanning is a systematic process for gathering and analyzing information about the external environment and relating it to an organization's internal environment.) This facilitator's guide is…

Keeping it wild in the National Park Service: A user guide to integrating wilderness character into park planning, management, and monitoring

Treesearch

Peter Landres; Suzy Stutzman; Wade Vagias; Carol Cook; Christina Mills; Tim Devine; Sandee Dingman; Adrienne Lindholm; Miki Stuebe; Melissa Memory; Ruth Scott; Michael Bilecki; Ray O' Neil; Chris Holbeck; Frank Turina; Michael Haynie; Sarah Craighead; Chip Jenkins; Jeremy Curtis; Karen Trevino

2014-01-01

This User Guide was developed to help National Park Service (NPS) staff effectively and efficiently fulfill the mandate from the 1964 Wilderness Act and NPS policy to "preserve wilderness character" now and into the future. This mandate applies to all congressionally designated wilderness and other park lands that are, by policy, managed as wilderness,...

Geometry and Algebra: The Future Flight Equation. A Lesson Guide with Activities in Mathematics, Science, and Technology. NASA CONNECT.

ERIC Educational Resources Information Center

National Aeronautics and Space Administration, Hampton, VA. Langley Research Center.

This activity, part of the NASA CONNECT Series, is designed to help students in grades 6-8 learn how NASA engineers develop experimental aircraft. It consists of an overview of the program, details of the hands-on activity, a series of blackline master student worksheets, teacher materials, and a guide to further resources. (MM)

NASTRAN thermal analyzer: Theory and application including a guide to modeling engineering problems, volume 2. [sample problem library guide

NASA Technical Reports Server (NTRS)

Jackson, C. E., Jr.

1977-01-01

A sample problem library containing 20 problems covering most facets of Nastran Thermal Analyzer modeling is presented. Areas discussed include radiative interchange, arbitrary nonlinear loads, transient temperature and steady-state structural plots, temperature-dependent conductivities, simulated multi-layer insulation, and constraint techniques. The use of the major control options and important DMAP alters is demonstrated.

Skills for Drug-Free Living Curriculum Guide. Future Quest.

ERIC Educational Resources Information Center

de la Garza, Bridget M.; And Others

The Future Quest curriculum is a functional curriculum to teach drug abuse prevention skills to youth with mild disabilities. The curriculum is a one-semester instructional program of lesson plans that incorporate research-based effective teaching practices and are specifically designed to meet the needs of students with learning and behavior…

Wired for the Future: Developing Your Library Technology Plan.

ERIC Educational Resources Information Center

Mayo, Diane; Nelson, Sandra

A technology plan provides a blueprint against which to measure new technologies and applications, assess future needs, and allocate resources to balance technology with the needs of users and staff. This book is a comprehensive and practical guide for librarians preparing a technology plan. The book is divided into five planning steps, each of…

The Future of Museums and Libraries: A Discussion Guide

ERIC Educational Resources Information Center

Institute of Museum and Library Services, 2009

2009-01-01

The Institute of Museum and Library Services (IMLS) is committed to bringing together museums and libraries across the country for conversations dedicated to developing a better understanding of the roles of libraries and museums as providers of public service to communities. The Future of Libraries and Museums in the 21st Century Planning…

Teaching about Conflict, Nuclear War and the Future.

ERIC Educational Resources Information Center

Zola, John; Sieck, Reny

Designed for teachers of students in grades 5-12, the guide provides over 25 lesson plans and 45 student handouts for teaching units on conflict, nuclear war, and future studies. In the first unit, students define conflict, learn conflict-related vocabulary, illustrate knowledge of conflict types through the use of cartoons, recognize common…

Equipped for the Future. Preparing for Work: A Guide for Business

ERIC Educational Resources Information Center

Center for Literacy Studies, University of Tennessee (NJ3), 2011

2011-01-01

"Preparing for Work," developed by Equipped for the Future at the Center for Literacy Studies, University of Tennessee, is a skills-based course designed for implementation in organizations and agencies involved in preparing their clients and students for entry level work. Each of the instructional modules that comprise the…

Future Language Teachers Learning to Become CALL Designers--Methodological Perspectives in Studying Complexity

ERIC Educational Resources Information Center

Keisanen, Tiina; Kuure, Leena

2015-01-01

Language teachers of the future, our current students, live in an increasingly technology-rich world. However, language students do not necessarily see their own digital practices as having relevance for guiding language learning. Research in the fields of CALL and language education more generally indicates that teaching practices change slowly…

77 FR 22234 - Notice of Intent To Request Public Comments

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-13

... consolidate future reviews of these rules with the next scheduled review of 16 CFR part 803. The Commission... schedule in the future to incorporate new rules, or to respond to external factors (such as changes in the... and 2018. Prohibitions Concerning Franchising. 681 Identity Theft [Red Flag] Rules.. 2018. 24 Guides...

[Personal Futures Planning: Building a Foundation for Individualized Transition Services.

ERIC Educational Resources Information Center

Carr, Theresa, Ed.

1993-01-01

These two newsletter special issues focus on personal futures planning (PFP) for people with deaf blindness, with emphasis on technical assistance activities involved in implementing a PFP program. PFP guides a team through three phases of activities: (1) developing a "circle of support" for an individual with deaf blindness; (2)…

Here Comes the Future.

ERIC Educational Resources Information Center

Reeder, Robert; And Others

This teacher's guide introduces students to problems and potentials of the future in an effort to prepare them for life in the 21st century. Based on an interdisciplinary approach, the lesson plans within four major units represent five futuristic trends and assumptions: (1) the shift of emphasis from subject matter to conceptual frameworks; (2)…

Analysis of Genetic Algorithm for Rule-Set Production (GARP) modeling approach for predicting distributions of fleas implicated as vectors of plague, Yersinia pestis, in California.

PubMed

Adjemian, Jennifer C Z; Girvetz, Evan H; Beckett, Laurel; Foley, Janet E

2006-01-01

More than 20 species of fleas in California are implicated as potential vectors of Yersinia pestis. Extremely limited spatial data exist for plague vectors-a key component to understanding where the greatest risks for human, domestic animal, and wildlife health exist. This study increases the spatial data available for 13 potential plague vectors by using the ecological niche modeling system Genetic Algorithm for Rule-Set Production (GARP) to predict their respective distributions. Because the available sample sizes in our data set varied greatly from one species to another, we also performed an analysis of the robustness of GARP by using the data available for flea Oropsylla montana (Baker) to quantify the effects that sample size and the chosen explanatory variables have on the final species distribution map. GARP effectively modeled the distributions of 13 vector species. Furthermore, our analyses show that all of these modeled ranges are robust, with a sample size of six fleas or greater not significantly impacting the percentage of the in-state area where the flea was predicted to be found, or the testing accuracy of the model. The results of this study will help guide the sampling efforts of future studies focusing on plague vectors.

Genetic variation, population structure and linkage disequilibrium in Switchgrass with ISSR, SCoT and EST-SSR markers.

PubMed

Zhang, Yu; Yan, Haidong; Jiang, Xiaomei; Wang, Xiaoli; Huang, Linkai; Xu, Bin; Zhang, Xinquan; Zhang, Lexin

2016-01-01

To evaluate genetic variation, population structure, and the extent of linkage disequilibrium (LD), 134 switchgrass ( Panicum virgatum L.) samples were analyzed with 51 markers, including 16 ISSRs, 20 SCoTs, and 15 EST-SSRs. In this study, a high level of genetic variation was observed in the switchgrass samples and they had an average Nei's gene diversity index (H) of 0.311. A total of 793 bands were obtained, of which 708 (89.28 %) were polymorphic. Using a parameter marker index (MI), the efficiency of the three types of markers (ISSR, SCoT, and EST-SSR) in the study were compared and we found that SCoT had a higher marker efficiency than the other two markers. The 134 switchgrass samples could be divided into two sub-populations based on STRUCTURE, UPGMA clustering, and principal coordinate analyses (PCA), and upland and lowland ecotypes could be separated by UPGMA clustering and PCA analyses. Linkage disequilibrium analysis revealed an average r 2 of 0.035 across all 51 markers, indicating a trend of higher LD in sub-population 2 than that in sub-population 1 ( P  < 0.01). The population structure revealed in this study will guide the design of future association studies using these switchgrass samples.

Impact of genomic profiling on the treatment and outcomes of patients with advanced gastrointestinal malignancies.

PubMed

Dhir, Mashaal; Choudry, Haroon A; Holtzman, Matthew P; Pingpank, James F; Ahrendt, Steven A; Zureikat, Amer H; Hogg, Melissa E; Bartlett, David L; Zeh, Herbert J; Singhi, Aatur D; Bahary, Nathan

2017-01-01

The impact of genomic profiling on the outcomes of patients with advanced gastrointestinal (GI) malignancies remains unknown. The primary objectives of the study were to investigate the clinical benefit of genomic-guided therapy, defined as complete response (CR), partial response (PR), or stable disease (SD) at 3 months, and its impact on progression-free survival (PFS) in patients with advanced GI malignancies. Clinical and genomic data of all consecutive GI tumor samples from April, 2013 to April, 2016 sequenced by FoundationOne were obtained and analyzed. A total of 101 samples from 97 patients were analyzed. Ninety-eight samples from 95 patients could be amplified making this approach feasible in 97% of the samples. After removing duplicates, 95 samples from 95 patients were included in the further analysis. Median time from specimen collection to reporting was 11 days. Genomic alteration-guided treatment recommendations were considered new and clinically relevant in 38% (36/95) of the patients. Rapid decline in functional status was noted in 25% (9/36) of these patients who could therefore not receive genomic-guided therapy. Genomic-guided therapy was utilized in 13 patients (13.7%) and 7 patients (7.4%) experienced clinical benefit (6 PR and 1 SD). Among these seven patients, median PFS was 10 months with some ongoing durable responses. Genomic profiling-guided therapy can lead to clinical benefit in a subset of patients with advanced GI malignancies. Attempting genomic profiling earlier in the course of treatment prior to functional decline may allow more patients to benefit from these therapies. © 2016 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

Multimodal 18F-Fluciclovine PET/MRI and Ultrasound-Guided Neurosurgery of an Anaplastic Oligodendroglioma.

PubMed

Karlberg, Anna; Berntsen, Erik Magnus; Johansen, Håkon; Myrthue, Mariane; Skjulsvik, Anne Jarstein; Reinertsen, Ingerid; Esmaeili, Morteza; Dai, Hong Yan; Xiao, Yiming; Rivaz, Hassan; Borghammer, Per; Solheim, Ole; Eikenes, Live

2017-12-01

Structural magnetic resonance imaging (MRI) and histopathologic tissue sampling are routinely performed as part of the diagnostic workup for patients with glioma. Because of the heterogeneous nature of gliomas, there is a risk of undergrading caused by histopathologic sampling errors. MRI has limitations in identifying tumor grade and type, detecting diffuse invasive growth, and separating recurrences from treatment induced changes. Positron emission tomography (PET) can provide quantitative information of cellular activity and metabolism, and may therefore complement MRI. In this report, we present the first patient with brain glioma examined with simultaneous PET/MRI using the amino acid tracer 18 F-fluciclovine ( 18 F-FACBC) for intraoperative image-guided surgery. A previously healthy 60-year old woman was admitted to the emergency care with speech difficulties and a mild left-sided hemiparesis. MRI revealed a tumor that was suggestive of glioma. Before surgery, the patient underwent a simultaneous PET/MRI examination. Fused PET/MRI, T1, FLAIR, and intraoperative three-dimensional ultrasound images were used to guide histopathologic tissue sampling and surgical resection. Navigated, image-guided histopathologic samples were compared with PET/MRI image data to assess the additional value of the PET acquisition. Histopathologic analysis showed anaplastic oligodendroglioma in the most malignant parts of the tumor, while several regions were World Health Organization (WHO) grade II. 18 F-Fluciclovine uptake was found in parts of the tumor where regional WHO grade, cell proliferation, and cell densities were highest. This finding suggests that PET/MRI with this tracer could be used to improve accuracy in histopathologic tissue sampling and grading, and possibly for guiding treatments targeting the most malignant part of extensive and eloquent gliomas. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

Cybersonics: Tapping into Technology

NASA Technical Reports Server (NTRS)

2001-01-01

With the assistance of Small Business Innovation Research (SBIR) funding from NASA's Jet Propulsion Laboratory, Cybersonics, Inc., developed an ultrasonic drill with applications ranging from the medical industry to space exploration. The drill, which has the ability to take a core sample of the hardest granite or perform the most delicate diagnostic medical procedure, is a lightweight, ultrasonic device made to fit in the palm of the hand. Piezoelectric actuators, which have only two moving parts and no gears or motors, drive the components of the device, enabling it to operate in a wide range of temperatures. The most remarkable aspect of the drill is its ability to penetrate even the hardest rock with minimal force application. The ultrasonic device requires 20 to 30 times less force than standard rotating drills, allowing it to be safely guided by hand during operation. Also, the drill is operable at a level as low as three watts of power, where conventional drills require more than three times this level. Potential future applications for the ultrasonic drill include rock and soil sampling, medical procedures that involve core sampling or probing, landmine detection, building and construction, and space exploration. Cybersonics, Inc. developed an ultrasonic drill with applications ranging from the medical industry to space exploration.

At the forefront: evidence of the applicability of using environmental DNA to quantify the abundance of fish populations in natural lentic waters with additional sampling considerations

USGS Publications Warehouse

Klobucar, Stephen L.; Rodgers, Torrey W.; Budy, Phaedra

2017-01-01

Environmental DNA (eDNA) sampling has proven to be a valuable tool for detecting species in aquatic ecosystems. Within this rapidly evolving field, a promising application is the ability to obtain quantitative estimates of relative species abundance based on eDNA concentration rather than traditionally labor-intensive methods. We investigated the relationship between eDNA concentration and Arctic char (Salvelinus alpinus) abundance in five well-studied natural lakes; additionally, we examined the effects of different temporal (e.g., season) and spatial (e.g., depth) scales on eDNA concentration. Concentrations of eDNA were linearly correlated with char population estimates ( = 0.78) and exponentially correlated with char densities ( = 0.96 by area; 0.82 by volume). Across lakes, eDNA concentrations were greater and more homogeneous in the water column during mixis; however, when stratified, eDNA concentrations were greater in the hypolimnion. Overall, our findings demonstrate that eDNA techniques can produce effective estimates of relative fish abundance in natural lakes. These findings can guide future studies to improve and expand eDNA methods while informing research and management using rapid and minimally invasive sampling.

Art Education Curriculum Guide, K-12.

ERIC Educational Resources Information Center

Naperville Public Schools, IL.

GRADES OR AGES: K-12. SUBJECT MATTER: Art. ORGANIZATION AND PHYSICAL APPEARANCE: The guide is divided into numerous sections, one each for grades K-8, and one section for grades 9-12. Each section is in list form. The guide is mimeographed and spiral-bound with a paper cover. OBJECTIVES AND ACTIVITIES: Each section contains four sample lessons…

Inside the Global Economy: Preview Guide to the Telecourse.

ERIC Educational Resources Information Center

Rabin, Steven

This document contains samples only of just the print components of a telecourse that includes: 13 videotapes, 2 videodiscs, a recommended textbook, a case-study reader and review guide, a text study guide, a faculty manual with text bank; and a computer softrware tutorial. This telecourse examines international global economies by means of 13…

A Curriculum Guide for Medical Record Technologist. Final Report.

ERIC Educational Resources Information Center

Garozzo, Joyce

This curriculum guide was developed as a result of a project conducted in Pennsylvania to review, update, and revise the vocational-technical manual on file in the Pennsylvania Department of Education and to develop sample curriculum for the preparation of a medical record technologist program using the skills developed in the manual. The guide is…

Spanish Oral Language Guide: Kindergarten Level. Espanol como Segundo Idioma. Teacher's Guide: Level I.

ERIC Educational Resources Information Center

Corbell, Gloria; And Others

This teacher's guide to Spanish language at the kindergarten level includes a recommended subject presentation sequence for the Spanish curriculum, a sample schedule, a grouping of students using three stations, and a classroom layout. The grouping would be effective when at least one-third of the children are Spanish-speaking or bilingual. The…

The Impact of Guided Reading Instruction on Elementary Students' Reading Fluency and Accuracy

ERIC Educational Resources Information Center

Teets, Agnes Jean

2017-01-01

This study examined the impact of Guided Reading instruction on elementary students' ability to read with fluency and accuracy. A one-way analysis of covariance with pre and posttest design was performed and applied to determine the impact of Guided Reading instruction on elementary students' reading fluency and accuracy. The sample of subjects…

Industrial Work Experience I. Curriculum Guide. General Related Study Units.

ERIC Educational Resources Information Center

Virginia Polytechnic Inst. and State Univ., Blacksburg. Div. of Vocational-Technical Education.

The primary purpose of this guide is to present basic sample instructional materials for the Industrial Work Experience (IWE) Program. It is designed to aid those charged with local administration and coordination of programs in secondary level trade and industrial education, referred to as the IWE training program. The guide contains 10 units of…

Import Auto Technician; Curriculum Guide for the Development of an Import Automobile Technology Program.

ERIC Educational Resources Information Center

East Los Angeles Coll., CA.

In this curriculum guide, courses in a three-phase community college program for training import automobile technicians are provided. Following an introducation to the guide, the background of the development of the program, the program, the instruction, support for instruction, and the import automobile industry are discussed. Sample options for…

“Maybe I Will Just Send a Quick Text…” – An Examination of Drivers’ Distractions, Causes, and Potential Interventions

PubMed Central

Johansson, Ole J.; Fyhri, Aslak

2017-01-01

Many people use cars all over the world. This is, however, not done without risk, as traffic accidents are one of the most common causes of death for adolescents worldwide. The number of deaths has steadily decreased, both worldwide and in Norway. Many of these accidents involve passenger cars and distracted driving. While there are many campaigns to improve safety in traffic, little research has looked at distractions. A recent report has investigated the occurrence of and damage caused by distraction, and one article has looked at what predicts baseline differences in levels of distracted driving. However, no one has tested an intervention to decrease distracted behavior in traffic. Motivational variables suggested by the Theory of Planned Behavior, personality traits, and demographic variables show utility in similar contexts and are all tested in this project. Data from two samples were collected to investigate the nature of distractions in traffic, what factors predict baseline levels of distractions, and to test an intervention to reduce distractions. Both samples feature randomly assigned intervention and control groups. The first sample (n = 1100 total; n = 208 was licensed to drive) consisted of high school students from all over Norway as a part of a larger attitudinal campaign, while the second sample (n = 414) was more general. The second tested a digital version of implementation intentions designed as volitional help sheets. The results from both samples suggest that there are some robust differences between people in how much they are distracted in everyday life, while some variables need further research. The second study failed to uncover any effects of the intervention. Reasons for this are discussed, along with points on the efficacy of digital interventions, the design of the volitional help sheets, and the design of the study in general. Notwithstanding the ineffectual interventions, this study contains novel information about baseline differences in distractive behavior that may further impact future behavior change interventions and guide future research. PMID:29204129

"Maybe I Will Just Send a Quick Text…" - An Examination of Drivers' Distractions, Causes, and Potential Interventions.

PubMed

Johansson, Ole J; Fyhri, Aslak

2017-01-01

Many people use cars all over the world. This is, however, not done without risk, as traffic accidents are one of the most common causes of death for adolescents worldwide. The number of deaths has steadily decreased, both worldwide and in Norway. Many of these accidents involve passenger cars and distracted driving. While there are many campaigns to improve safety in traffic, little research has looked at distractions. A recent report has investigated the occurrence of and damage caused by distraction, and one article has looked at what predicts baseline differences in levels of distracted driving. However, no one has tested an intervention to decrease distracted behavior in traffic. Motivational variables suggested by the Theory of Planned Behavior, personality traits, and demographic variables show utility in similar contexts and are all tested in this project. Data from two samples were collected to investigate the nature of distractions in traffic, what factors predict baseline levels of distractions, and to test an intervention to reduce distractions. Both samples feature randomly assigned intervention and control groups. The first sample ( n = 1100 total; n = 208 was licensed to drive) consisted of high school students from all over Norway as a part of a larger attitudinal campaign, while the second sample ( n = 414) was more general. The second tested a digital version of implementation intentions designed as volitional help sheets. The results from both samples suggest that there are some robust differences between people in how much they are distracted in everyday life, while some variables need further research. The second study failed to uncover any effects of the intervention. Reasons for this are discussed, along with points on the efficacy of digital interventions, the design of the volitional help sheets, and the design of the study in general. Notwithstanding the ineffectual interventions, this study contains novel information about baseline differences in distractive behavior that may further impact future behavior change interventions and guide future research.

Fast 3-T MR-guided transrectal prostate biopsy using an in-room tablet device for needle guide alignment: a feasibility study.

PubMed

Overduin, Christiaan G; Heidkamp, Jan; Rothgang, Eva; Barentsz, Jelle O; de Lange, Frank; Fütterer, Jurgen J

2018-05-22

To assess the feasibility of adding a tablet device inside the scanner room to assist needle-guide alignment during magnetic resonance (MR)-guided transrectal prostate biopsy. Twenty patients with one cancer-suspicious region (CSR) with PI-RADS score ≥ 4 on diagnostic multiparametric MRI were prospectively enrolled. Two orthogonal scan planes of an MR fluoroscopy sequence (~3 images/s) were aligned to the CSR and needle-guide pivoting point. Targeting was achieved by manipulating the needle-guide under MR fluoroscopy feedback on the in-room tablet device. Technical feasibility and targeting success were assessed. Complications and biopsy procedure times were also recorded. Needle-guide alignment with the in-room tablet device was technically successful in all patients and allowed sampling after a single alignment step in 19/20 (95%) CSRs (median size 14 mm, range: 4-45). Biopsy cores contained cancer in 18/20 patients. There were no per-procedural or post-biopsy complications. Using the tablet device, the mean time to first biopsy was 5.8 ± 1.0 min and the mean total procedure time was 23.7 ± 4.1 min. Use of an in-room tablet device to assist needle-guide alignment was feasible and safe during MR-guided transrectal prostate biopsy. Initial experience indicates potential for procedure time reduction. • Performing MR-guided prostate biopsy using an in-room tablet device is feasible. • CSRs could be sampled after a single alignment step in 19/20 patients. • The mean procedure time for biopsy with the tablet device was 23.7 min.

A circumpolar monitoring framework for polar bears

USGS Publications Warehouse

Vongraven, Dag; Aars, Jon; Amstrup, Steven C.; Atkinson, Stephen N.; Belikov, Stanislav; Born, Erik W.; DeBruyn, T.D.; Derocher, Andrew E.; Durner, George M.; Gill, Michael J.; Lunn, Nicholas J.; Obbard, Martyn E.; Omelak, Jack; Ovsyanikov, Nikita; Peacock, Elizabeth; Richardson, E.E.; Sahanatien, Vicki; Stirling, Ian; Wiig, Øystein

2012-01-01

Polar bears (Ursus maritimus) occupy remote regions that are characterized by harsh weather and limited access. Polar bear populations can only persist where temporal and spatial availability of sea ice provides adequate access to their marine mammal prey. Observed declines in sea ice availability will continue as long as greenhouse gas concentrations rise. At the same time, human intrusion and pollution levels in the Arctic are expected to increase. A circumpolar understanding of the cumulative impacts of current and future stressors is lacking, long-term trends are known from only a few subpopulations, and there is no globally coordinated effort to monitor effects of stressors. Here, we describe a framework for an integrated circumpolar monitoring plan to detect ongoing patterns, predict future trends, and identify the most vulnerable polar bear subpopulations. We recommend strategies for monitoring subpopulation abundance and trends, reproduction, survival, ecosystem change, human-caused mortality, human–bear conflict, prey availability, health, stature, distribution, behavioral change, and the effects that monitoring itself may have on polar bears. We assign monitoring intensity for each subpopulation through adaptive assessment of the quality of existing baseline data and research accessibility. A global perspective is achieved by recommending high intensity monitoring for at least one subpopulation in each of four major polar bear ecoregions. Collection of data on harvest, where it occurs, and remote sensing of habitat, should occur with the same intensity for all subpopulations. We outline how local traditional knowledge may most effectively be combined with the best scientific methods to provide comparable and complementary lines of evidence. We also outline how previously collected intensive monitoring data may be sub-sampled to guide future sampling frequencies and develop indirect estimates or indices of subpopulation status. Adoption of this framework will inform management and policy responses to changing worldwide polar bear status and trends.

Image-guided techniques in renal and hepatic interventions.

PubMed

Najmaei, Nima; Mostafavi, Kamal; Shahbazi, Sahar; Azizian, Mahdi

2013-12-01

Development of new imaging technologies and advances in computing power have enabled the physicians to perform medical interventions on the basis of high-quality 3D and/or 4D visualization of the patient's organs. Preoperative imaging has been used for planning the surgery, whereas intraoperative imaging has been widely employed to provide visual feedback to a clinician when he or she is performing the procedure. In the past decade, such systems demonstrated great potential in image-guided minimally invasive procedures on different organs, such as brain, heart, liver and kidneys. This article focuses on image-guided interventions and surgery in renal and hepatic surgeries. A comprehensive search of existing electronic databases was completed for the period of 2000-2011. Each contribution was assessed by the authors for relevance and inclusion. The contributions were categorized on the basis of the type of operation/intervention, imaging modality and specific techniques such as image fusion and augmented reality, and organ motion tracking. As a result, detailed classification and comparative study of various contributions in image-guided renal and hepatic interventions are provided. In addition, the potential future directions have been sketched. With a detailed review of the literature, potential future trends in development of image-guided abdominal interventions are identified, namely, growing use of image fusion and augmented reality, computer-assisted and/or robot-assisted interventions, development of more accurate registration and navigation techniques, and growing applications of intraoperative magnetic resonance imaging. Copyright © 2012 John Wiley & Sons, Ltd.

National Symposium on Effective Communication for Children and Youth with Severe Disabilities (2nd, McLean, Virginia, July 10-12, 1992): Topic Papers, Reader's Guide & Videotape.

ERIC Educational Resources Information Center

Kupper, Lisa, Ed.

This combined audiovisual and textual package presents results of a symposium which attempted to identify critical issues and best practices in developing communication skills of children and youth with severe disabilities and to recommend future directions. The package is intended for group use and includes a guide, a videotape, and texts of the…

Find Your Future: A Career-Planning Guide in Science, Mathematics, and Engineering for Precollege Students with Disabilities and the Adults Who Work with Them. Second Edition.

ERIC Educational Resources Information Center

DuBois, Phyllis; Weisgerber, Robert

This career planning guide is intended for precollege students with disabilities who desire careers in science, mathematics, or engineering. The booklet reflects the experiences and advice of 286 individuals with disabilities who are in these careers or preparing for them. The first section summarizes the advantages of a career in these fields,…

Guide to GFS History File Change on May 1, 2007

Science.gov Websites

Guide to GFS History File Change on May 1, 2007 On May 1, 2007 12Z, the GFS had a major change. The change caused the internal binary GFS history file to change formats. The file is still in spectral space but now pressure is calculated in a different way. Sometime in the future, the GFS history file may be

Planning, Development, and Change in Bristol Bay: A High School Curriculum. Teacher Guide and Student Text. Unit I: Introduction. Unit II: Village Corporations. Revised.

ERIC Educational Resources Information Center

Lipka, Jerry; Willer, Cristy

This combined teacher guide and student text is written with the broad goal of involving high school students in Bristol Bay, Alaska, in the planning and design of their region's future. Unit I introduces changes occurring on village and regional levels, discusses planning strategies for community development, and presents village profiles for…

To Your Credit. FDIC Money Smart Financial Education Curriculum = Su Credito y Usted. FDIC Money Smart Plan de Educacion para Capacitacion en Finanzas.

ERIC Educational Resources Information Center

Federal Deposit Insurance Corp., Washington, DC.

This module on how one's credit history will affect one's credit future is one of ten in the Money Smart curriculum, and includes an instructor guide and a take-home guide. It was developed to help adults outside the financial mainstream enhance their money skills and create positive banking relationships. It is designed to make participants…

Charging Toward an Even Brighter Future

DTIC Science & Technology

2011-01-01

counterparts, but rather seeking to be treated with equal recognition in all aspects such as protocol , etiquette , housing, and evaluation reporting...grade as well as GS-12 or higher. When consid- ered with other regulations such as DA PAM 600-60 (A Guide to Protocol and Etiquette for Official...PAM 600-60 (A Guide to Protocol and Etiquette for Official Enter- tainment) contains a table which lists the precedence of civilian and military

Lesion with morphologic feature of organizing pneumonia (OP) in CT-guided lung biopsy samples for diagnosis of bronchiolitis obliterans organizing pneumonia (BOOP): a retrospective study of 134 cases in a single center.

PubMed

Miao, Liyun; Wang, Yongsheng; Li, Yan; Ding, Jingjing; Chen, Lulu; Dai, Jinghong; Cai, Hourong; Xiao, Yonglong; Cao, Min; Huang, Mei; Qiu, Yuying; Meng, Fanqing; Fan, Xiangshan; Zhang, Deping; Song, Yong

2014-09-01

Small biopsy samples are generally considered inconclusive for bronchiolitis obliterans organizing pneumonia (BOOP) diagnosis despite their potential to reveal organizing pneumonia (OP) pathologically, necessitating risky invasive tissue biopsy during surgery for reliable confirmation. OP by CT-guided lung biopsy was to evaluate the role in the diagnosis of BOOP. A retrospective review of 134 cases with the OP feature in the CT-guided lung biopsy samples between 2004 and 2011 at a single center was conducted. Diagnostic accuracy of OP by CT-guided lung biopsy and clinical-radiographic data alone were compared. After exclusion of 11 cases due to pathology with others besides OP and 15 cases for loss to follow-up, 108 were included. Of these, 95 cases and 13 cases were classified as BOOP and non-BOOP group, respectively. Among BOOP group, only 30 were initially diagnosed as BOOP according to the typical clinical and radiographic features. The other 65 cases with atypical features were diagnosed as BOOP mainly based on OP by CT-guided lung biopsy. Among non-BOOP group, one was misdiagnosed as BOOP, and others were not BOOP according to clinical and radiographic findings. Thus, OP by CT-guided lung biopsy produced a diagnostic accuracy of 87.96% (95/108), much higher than 31.25% (30/96) observed using clinical and radiographic data alone. Combined, these techniques produced diagnostic accuracy of 98.96% (95/96). OP by CT-guided lung biopsy can be effectively used as the pathological evidence for BOOP diagnosis and reducing unnecessary surgery.

Lesion with morphologic feature of organizing pneumonia (OP) in CT-guided lung biopsy samples for diagnosis of bronchiolitis obliterans organizing pneumonia (BOOP): a retrospective study of 134 cases in a single center

PubMed Central

Wang, Yongsheng; Li, Yan; Ding, Jingjing; Chen, Lulu; Dai, Jinghong; Cai, Hourong; Xiao, Yonglong; Cao, Min; Huang, Mei; Qiu, Yuying; Meng, Fanqing; Fan, Xiangshan; Zhang, Deping

2014-01-01

Background Small biopsy samples are generally considered inconclusive for bronchiolitis obliterans organizing pneumonia (BOOP) diagnosis despite their potential to reveal organizing pneumonia (OP) pathologically, necessitating risky invasive tissue biopsy during surgery for reliable confirmation. Objective OP by CT-guided lung biopsy was to evaluate the role in the diagnosis of BOOP. Methods A retrospective review of 134 cases with the OP feature in the CT-guided lung biopsy samples between 2004 and 2011 at a single center was conducted. Diagnostic accuracy of OP by CT-guided lung biopsy and clinical-radiographic data alone were compared. Results After exclusion of 11 cases due to pathology with others besides OP and 15 cases for loss to follow-up, 108 were included. Of these, 95 cases and 13 cases were classified as BOOP and non-BOOP group, respectively. Among BOOP group, only 30 were initially diagnosed as BOOP according to the typical clinical and radiographic features. The other 65 cases with atypical features were diagnosed as BOOP mainly based on OP by CT-guided lung biopsy. Among non-BOOP group, one was misdiagnosed as BOOP, and others were not BOOP according to clinical and radiographic findings. Thus, OP by CT-guided lung biopsy produced a diagnostic accuracy of 87.96% (95/108), much higher than 31.25% (30/96) observed using clinical and radiographic data alone. Combined, these techniques produced diagnostic accuracy of 98.96% (95/96). Conclusions OP by CT-guided lung biopsy can be effectively used as the pathological evidence for BOOP diagnosis and reducing unnecessary surgery. PMID:25276367

Visual Sample Plan Version 7.0 User's Guide

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matzke, Brett D.; Newburn, Lisa LN; Hathaway, John E.

2014-03-01

User's guide for VSP 7.0 This user's guide describes Visual Sample Plan (VSP) Version 7.0 and provides instructions for using the software. VSP selects the appropriate number and location of environmental samples to ensure that the results of statistical tests performed to provide input to risk decisions have the required confidence and performance. VSP Version 7.0 provides sample-size equations or algorithms needed by specific statistical tests appropriate for specific environmental sampling objectives. It also provides data quality assessment and statistical analysis functions to support evaluation of the data and determine whether the data support decisions regarding sites suspected of contamination.more » The easy-to-use program is highly visual and graphic. VSP runs on personal computers with Microsoft Windows operating systems (XP, Vista, Windows 7, and Windows 8). Designed primarily for project managers and users without expertise in statistics, VSP is applicable to two- and three-dimensional populations to be sampled (e.g., rooms and buildings, surface soil, a defined layer of subsurface soil, water bodies, and other similar applications) for studies of environmental quality. VSP is also applicable for designing sampling plans for assessing chem/rad/bio threat and hazard identification within rooms and buildings, and for designing geophysical surveys for unexploded ordnance (UXO) identification.« less

Contribution of 3D printing to mandibular reconstruction after cancer.

PubMed

Dupret-Bories, A; Vergez, S; Meresse, T; Brouillet, F; Bertrand, G

2018-04-01

Three-dimensional (3D) printing is booming in the medical field. This technology increases the possibilities of personalized treatment for patients, while lowering manufacturing costs. To facilitate mandibular reconstruction with fibula free flap, some companies propose cutting guides obtained by CT-guided moulding. However, these guides are prohibitively expensive (€2,000 to €6,000). Based on a partnership with the CNRS, engineering students and a biomedical company, the authors have developed cutting guides and 3D-printed mandible templates, deliverable in 7days and at a lower cost. The novelty of this project is the speed of product development at a significantly lower price. In this technical note, the authors describe the logistic chain of production of mandible templates and cutting guides, as well as the results obtained. The goal is to allow access to this technology to all patients in the near future. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Computer-aided design and manufacturing of surgical templates and their clinical applications: a review.

PubMed

Chen, Xiaojun; Xu, Lu; Wang, Wei; Li, Xing; Sun, Yi; Politis, Constantinus

2016-09-01

The surgical template is a guide aimed at directing the implant placement, tumor resection, osteotomy and bone repositioning. Using it, preoperative planning can be transferred to the actual surgical site, and the precision, safety and reliability of the surgery can be improved. However, the actual workflow of the surgical template design and manufacturing is quite complicated before the final clinical application. The major goal of the paper is to provide a comprehensive reference source of the current and future development of the template design and manufacturing for relevant researchers. Expert commentary: This paper aims to present a review of the necessary procedures in the template-guided surgery including the image processing, 3D visualization, preoperative planning, surgical guide design and manufacturing. In addition, the template-guided clinical applications for various kinds of surgeries are reviewed, and it demonstrated that the precision of the surgery has been improved compared with the non-guided operations.

Prosthetically directed implant placement using computer software to ensure precise placement and predictable prosthetic outcomes. Part 2: rapid-prototype medical modeling and stereolithographic drilling guides requiring bone exposure.

PubMed

Rosenfeld, Alan L; Mandelaris, George A; Tardieu, Philippe B

2006-08-01

The purpose of this paper is to expand on part 1 of this series (published in the previous issue) regarding the emerging future of computer-guided implant dentistry. This article will introduce the concept of rapid-prototype medical modeling as well as describe the utilization and fabrication of computer-generated surgical drilling guides used during implant surgery. The placement of dental implants has traditionally been an intuitive process, whereby the surgeon relies on mental navigation to achieve optimal implant positioning. Through rapid-prototype medical modeling and the ste-reolithographic process, surgical drilling guides (eg, SurgiGuide) can be created. These guides are generated from a surgical implant plan created with a computer software system that incorporates all relevant prosthetic information from which the surgical plan is developed. The utilization of computer-generated planning and stereolithographically generated surgical drilling guides embraces the concept of collaborative accountability and supersedes traditional mental navigation on all levels of implant therapy.

WISE infrared properties of OH megamaser galaxies: Guide for future FAST OHM searching?

NASA Astrophysics Data System (ADS)

Zhang, JiangShui; Wang, JunZhi; Li, Di

2015-08-01

All 119 OH maser galaxies (110 out of them are megamasers, i.e., LOH > 10 Lsun) published so far were compiled and were cross-identified with the Wide-Field Infrared Survey Explorer (WISE) catalog, to investigate the middle infrared (MIR) properties of OH maser galaxies. The WISE magnitude data at the 3.4, 4.6, 12 and 22 μm (W1 to W4 band) were collected for the OH maser sample and one control sample, which are non-detection sources. The color-color diagrams show that both OH megamaser (OHM) and non-OHM (ultra)luminous infrared galaxies ((U)LIRGs) are far away from the single blackbody model line and many of them can follow the path described by the power-law model. The active galaxy nuclei (AGN) fraction is about 40% for both OHM and non-OHM (U)LIRGs, according to the AGN criteria W1-W2 ≥ 0.8. Among the Arecibo survey sample, OHM sources tend to have a lower luminosity at short MIR wavelengths (e.g., 3.4 μm and 4.6 μm) than that of non-OHM sources, which should come from the low OHM fraction among the survey sample with large 3.4 μm and 4.6 μm luminosity. The OHM fraction tends to increase with cooler MIR colors (larger F22 μm/F3.4 μm). In the case of the power-law model, we derived the spectral indices for our samples. For the Arecibo survey sample, OHM (U)LIRGs tend to have larger spectral index α22-12 than non-OHM sources, which agrees with previous results. One significant correlation exists between the WISE infrared luminosity at 22 μm and the color [W1]-[W4] for the Arecibo OHM hosts. In summary, these clues should provide suitable constraints on the sample selection for future OH megamaser surveys through the Five hundred aperture spherical telescope (FAST). Further potentials on FAST OH megamasers research are investigated, including detectability, sky density of OH megamasers etc.

Ocean Literacy Alliance-Hawaii (OLA-HI) Resource Guide

NASA Astrophysics Data System (ADS)

Bruno, B. C.; Rivera, M.; Hicks Johnson, T.; Baumgartner, E.; Davidson, K.

2008-05-01

The Ocean Literacy Alliance-Hawaii (OLA-HI) was founded in 2007 to establish a framework for collaboration in ocean science education in Hawaii. OLA-HI is supported by the federal Interagency Working Group-Ocean Education (IWG-OE) and funded through NSF and NOAA. Hawaii support is provided through the organizations listed above in the authors' block. Our inaugural workshop was attended by 55 key stakeholders, including scientists, educators, legislators, and representatives of federal, state, and private organizations and projects in Hawaii. Participants reviewed ongoing efforts, strengthened existing collaborations, and developed strategies to build new partnerships. Evaluations showed high satisfaction with the workshop, with 100% of respondents ranking the overall quality as `good' or `excellent'. Expected outcomes include a calendar of events, a website (www.soest.hawaii.edu/OLAHawaii), a list serve, and a resource guide for ocean science education in Hawaii. These products are all designed to facilitate online and offline networking and collaboration among Hawaii's ocean science educators. The OLA-HI resource guide covers a gamut of marine resources and opportunities, including K-12 curriculum, community outreach programs, museum exhibits and lecture series, internships and scholarships, undergraduate and graduate degree programs, and teacher professional development workshops. This guide is designed to share existing activities and products, minimize duplication of efforts, and help provide gap analysis to steer the direction of future ocean science projects and programs in Hawaii. We ultimately plan on using the resource guide to develop pathways to guide Hawaii's students toward ocean-related careers. We are especially interested in developing pathways for under-represented students in the sciences, particularly Native Hawaiians and Pacific Islanders, and will focus on this topic at a future OLA-HI workshop.

Endoscopic Ultrasound-Guided Fine Needle Aspiration: From the Past to the Future

PubMed Central

Costache, Mădălin-Ionuț; Iordache, Sevastița; Karstensen, John Gásdal; Săftoiu, Adrian; Vilmann, Peter

2013-01-01

Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a technique which allows the study of cells obtained through aspiration in different locations near the gastrointestinal tract. EUS-FNA is used to acquire tissue from mucosal/submucosal tumors, as well as peri-intestinal structures including lymph nodes, pancreas, adrenal gland, gallbladder, bile duct, liver, kidney, lung, etc. The pancreas and lymph nodes are still the most common organs targeted in EUS-FNA. The overall accuracy of EUS is superior to computed tomography scan and magnetic resonance imaging for detecting pancreatic lesions. In most cases it is possible to avoid unnecessary surgical interventions in advanced pancreatic cancer, and EUS is considered the preferred method for loco-regional staging of pancreatic cancer. FNA improved the sensitivity and specificity compared to EUS imaging alone in detection of malignant lymph nodes. The negative predictive value of EUS-FNA is relatively low. The presence of a cytopathologist during EUS-FNA improves the diagnostic yield, decreasing unsatisfactory samples or need for additional passes, and consequently the procedural time. The size of the needle is another factor that could modify the diagnostic accuracy of EUS-FNA. Even though the EUS-FNA technique started in early nineteen's, there are many remarkable progresses culminating nowadays with the discovery and performance of needle-based confocal laser endomicroscopy. Last, but not least, identification and quantification of potential molecular markers for pancreatic cancer on cellular samples obtained by EUS-FNA could be a promising approach for the diagnosis of solid pancreatic masses. PMID:24949369

Categorizing Others and the Self: How Social Memory Structures Guide Social Perception and Behavior

ERIC Educational Resources Information Center

Quinn, Kimberly A.; Rosenthal, Harriet E. S.

2012-01-01

In keeping with the special issue theme of "Remembering the Future," this article provides a selective review of research on how memory for social information (i.e., social category representation) influences future processing and behavior. Specifically, the authors focus on how categorization and stereotyping affect how we perceive others and…

The Meaning of the Future for the Oldest Old

ERIC Educational Resources Information Center

Nilsson, Margareta; Sarvimaki, Anneli; Ekman, Sirkka-Liisa

2003-01-01

The aim of the study was to highlight the oldest old people's view of their future from a perspective of philosophy of life. Data was collected by means of life story interviews with 15 persons. The analysis was performed by utilizing a phenomenological hermeneutic method and the interpretation was guided by the conceptual framework of philosophy…

The Peace Catalog: A Guidebook to a Positive Future.

ERIC Educational Resources Information Center

Sweeney, Duane, Ed.

This guidebook to a positive future provides (1) articles and essays covering all aspects of peace by leading experts on peace and nuclear war education, (2) a directory and detailed information on over 1,000 peace organizations, (3) a guide to socially responsible investing, and (4) a list of related reference books, publications, and films. The…

Play or Learn: European-American and Chinese Kindergartners' Perceptions about the Conflict

ERIC Educational Resources Information Center

Li, Jin

2016-01-01

Background: Kindergarten is the age at which children's future time perspective emerges. This capacity enables them to form goals based on past and ongoing experiences and project themselves in the future. This development may play an important role in guiding children in self-regulated learning. When faced with the conflict between their need to…

Technology Informatics Guiding Education Reform (TIGER). The Future of Interprofessional Education Is Here!

PubMed

Kuo, Ming-Chuan; Ball, Marion; Skiba, Diane J; Marin, Heimar; Shaw, Toria; Chang, Polun

2018-01-01

This session will describe the TIGER Initiative journey, its evolution and accomplishments nationally and internationally. A powerful demonstration of the TIGER Virtual Learning Environment (VLE) will be highlighted along with case studies from around the world, with emphasis on global competencies and opportunities for engagement in all current TIGER activities and future plans.

Viewing the Future of University Research Libraries through the Perspectives of Scenarios

ERIC Educational Resources Information Center

Cawthorne, Jon Edward

2013-01-01

This research highlights the scenarios that might serve as a strategic vision to describe a future beyond the current library, one which both guides provosts and creates a map for the transformation of human resources and technology in the university research libraries. The scenarios offer managerial leaders an opportunity to envision new roles…

Future Scenarios in Communications. [Student's Guide.] Preparing for Tomorrow's World.

ERIC Educational Resources Information Center

Iozzi, Louis A.; And Others

The purpose of this module is to introduce students (grades 7-8) to the concept of change and factors influencing change. The module is composed of two major sections. Section 1 examines the development of the telephone system in the United States and introduces four futures forecasting techniques (Delphi probe, cross-impact matrix, trend…

Overview: What's Worked and What Hasn't as a Guide towards Predictive Admissions Tool Development

ERIC Educational Resources Information Center

Siu, Eric; Reiter, Harold I.

2009-01-01

Admissions committees and researchers around the globe have used diligence and imagination to develop and implement various screening measures with the ultimate goal of predicting future clinical and professional performance. What works for predicting future job performance in the human resources world and in most of the academic world may not,…

Now...and the Future: A Guide for Families with Handicapped Children and Adults. First Edition.

ERIC Educational Resources Information Center

Hedgecock, Henry H.; And Others

Intended for parents of disabled children, the handbook addresses issues of estate planning and other legal matters concerning the child's future. An initial section on guardianship covers such aspects as how to obtain guardianship, duties, and alternatives to guardianships. Wills and trusts are examined in separate chapters which include…

Look into the Future: Displaced Clerical Project. Final Report.

ERIC Educational Resources Information Center

Stover, Deborah A.

"Look into the Future" is a program created by a Job Training Partnership Act project and 9to5, Working Women Education Fund, to address the training and retraining needs of office workers in light of the advances in computer and communications systems. This guide describes the model project and suggests steps other organizations can…

Guide to Education: ECS to Grade 12

ERIC Educational Resources Information Center

Alberta Education, 2008

2008-01-01

Education is the key to young people becoming full partners in shaping a global future and in shaping the nation's future. Quality basic education for young people is key to maintaining Alberta's standard of living and ensuring competitiveness in the world market. The education system must focus on what all students need to learn and be able to…

Researching Possible Futures to Guide Leaders towards More Effective Tertiary Education

ERIC Educational Resources Information Center

Davis, Niki; Higgins, Andrew

2015-01-01

This research aimed to inform institutional leaders by producing and disseminating a system wide view of what tertiary education might look like in Aotearoa New Zealand, five years into the future. The researchers were responding to a challenge in a speech at the DEANZ 2010 conference by a highly respected national leader (Dr. Peter Coolbear). The…

Explore Elementary Teachers' Professional Knowledge of Guiding Science Fair Product by Using Different Instruction Model

ERIC Educational Resources Information Center

Lu, Chow-Chin

2013-01-01

This research is about using two different instruction models, "theory course combined with sample introduction" and "theory course combined with case method teaching", to instruct elementary teachers on how to guide the science fair product in two courses (16 and 12 teachers in each class) and observe their guiding tactics after the instructed…

Structural dynamics payload loads estimates: User guide

NASA Technical Reports Server (NTRS)

Shanahan, T. G.; Engels, R. C.

1982-01-01

This User Guide with an overview of an integration scheme to determine the response of a launch vehicle with multiple payloads. Chapter II discusses the software package associated with the integration scheme together with several sample problems. A short cut version of the integration technique is also discussed. The Guide concludes with a list of references and the listings of the subroutines.

Ultrasonic Guided Waves for Aging Wire Insulation Assessment

NASA Technical Reports Server (NTRS)

Anastasi, Robert F.; Madaras, Eric I.

2001-01-01

Environmentally aged wire insulation can become brittle and crack and thus expose the underlying conductive wire to the potential for short circuits and fire. The feasibility of using ultrasonic guided waves to measure insulation condition was examined. First a simple model to study guided wave propagation in a bare and thin plastic coated wire was examined and then some aviation grade wire samples that had been heat-damaged. Initial measurements indicate that ultrasonic guided wave velocity can be used to monitor insulation stiffness.

Force-momentum-based self-guided Langevin dynamics: A rapid sampling method that approaches the canonical ensemble

NASA Astrophysics Data System (ADS)

Wu, Xiongwu; Brooks, Bernard R.

2011-11-01

The self-guided Langevin dynamics (SGLD) is a method to accelerate conformational searching. This method is unique in the way that it selectively enhances and suppresses molecular motions based on their frequency to accelerate conformational searching without modifying energy surfaces or raising temperatures. It has been applied to studies of many long time scale events, such as protein folding. Recent progress in the understanding of the conformational distribution in SGLD simulations makes SGLD also an accurate method for quantitative studies. The SGLD partition function provides a way to convert the SGLD conformational distribution to the canonical ensemble distribution and to calculate ensemble average properties through reweighting. Based on the SGLD partition function, this work presents a force-momentum-based self-guided Langevin dynamics (SGLDfp) simulation method to directly sample the canonical ensemble. This method includes interaction forces in its guiding force to compensate the perturbation caused by the momentum-based guiding force so that it can approximately sample the canonical ensemble. Using several example systems, we demonstrate that SGLDfp simulations can approximately maintain the canonical ensemble distribution and significantly accelerate conformational searching. With optimal parameters, SGLDfp and SGLD simulations can cross energy barriers of more than 15 kT and 20 kT, respectively, at similar rates for LD simulations to cross energy barriers of 10 kT. The SGLDfp method is size extensive and works well for large systems. For studies where preserving accessible conformational space is critical, such as free energy calculations and protein folding studies, SGLDfp is an efficient approach to search and sample the conformational space.

Modifications to Optimize the AH-1Z Human Machine Interface

DTIC Science & Technology

2013-04-18

accomplish this, a complete workload study of tasks performed by aircrew in the AH-1Z must be completed in the near future in order to understand...design flaws and guide future design and integration of increased capability. Additionally, employment of material solutions to provide aircrew with the...accomplish this, a complete workload study of tasks performed by aircrew in the AH-1Z must be completed in the near future in order to understand

Future land use threats to range-restricted fish species in the United States

DOE PAGES

Januchowski-Hartley, Stephanie R.; Holtz, Lauren A.; Martinuzzi, Sebastian; ...

2016-03-04

Land use change is one major threat to freshwater biodiversity, and land use change scenarios can help to assess threats from future land use change, thereby guiding proactive conservation decisions. Furthermore, our goal was to identify which range-restricted freshwater fish species are most likely to be affected by land use change and to determine where threats to these species from future land use change in the conterminous United States are most pronounced.

Future land use threats to range-restricted fish species in the United States

DOE Office of Scientific and Technical Information (OSTI.GOV)

Januchowski-Hartley, Stephanie R.; Holtz, Lauren A.; Martinuzzi, Sebastian

Land use change is one major threat to freshwater biodiversity, and land use change scenarios can help to assess threats from future land use change, thereby guiding proactive conservation decisions. Furthermore, our goal was to identify which range-restricted freshwater fish species are most likely to be affected by land use change and to determine where threats to these species from future land use change in the conterminous United States are most pronounced.

High temperature superconductor dc-SQUID microscope with a soft magnetic flux guide

NASA Astrophysics Data System (ADS)

Poppe, U.; Faley, M. I.; Zimmermann, E.; Glaas, W.; Breunig, I.; Speen, R.; Jungbluth, B.; Soltner, H.; Halling, H.; Urban, K.

2004-05-01

A scanning SQUID microscope based on high-temperature superconductor (HTS) dc-SQUIDs was developed. An extremely soft magnetic amorphous foil was used to guide the flux from room temperature samples to the liquid-nitrogen-cooled SQUID sensor and back. The flux guide passes through the pick-up loop of the HTS SQUID, providing an improved coupling of magnetic flux of the object to the SQUID. The device measures the z component (direction perpendicular to the sample surface) of the stray field of the sample, which is rastered with submicron precision in the x-y direction by a motorized computer-controlled scanning stage. A lateral resolution better than 10 µm, with a field resolution of about 0.6 nT Hz-1/2 was achieved for the determination of the position of the current carrying thin wires. The presence of the soft magnetic foil did not significantly increase the flux noise of the SQUID.

The worker of the future. A system outlines the competencies its employees will need.

PubMed

Hill, K; Meyer, B

1998-01-01

In 1993, Sisters of Mercy Health System-St. Louis (SMHS), having asked itself what kind of employees it would need in the twenty-first century, established a Worker of the Future Task Force to develop tentative answers. The task force began by making projections concerning healthcare, studying the strategic plans of SMHS's members, and surveying its employees. It learned that the system should help workers see how change could benefit them. Next, the task force studied the cultural history of the Sisters of Mercy, developing from it Six Guiding Principles for the evaluation of employee performance. From these principles, the task force derived Twelve Competencies that SMHS will seek in future workers. In 1995 the system's education leaders, with the aid of an internal training organization, decided to develop 17 training modules based on these guiding principles and competencies. Since then, more than 85 SMHS employees have been trained to help coworkers develop customer service skills and other competencies. SMHS has also incorporated the competencies in its job descriptions and performance evaluations, added the Worker of the Future curriculum to its orientation program for new employees, and is currently developing Worker of the Future training sessions for human resources personnel who interview prospective employees.

Long-term pavement performance project laboratory materials testing and handling guide

DOT National Transportation Integrated Search

2007-09-01

The Long Term Pavement Performance (LTPP) Laboratory Material Testing Guide was originally prepared for laboratory material handling and testing of material specimens and samples of asphalt materials, portland cement concrete, aggregates, and soils u...

Endobronchial ultrasound-guided transbronchial needle aspiration of thyroid: Report of two cases and systematic review of literature

PubMed Central

Madan, Karan; Mittal, Saurabh; Hadda, Vijay; Jain, Deepali; Mohan, Anant; Guleria, Randeep

2016-01-01

Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive and safe technique for a sampling of mediastinal lesions. Indications for EBUS-TBNA have gradually expanded since its introduction. The usual approach to cytological sampling of the thyroid gland is percutaneous ultrasound-guided fine needle aspiration (US-FNA) performed under local anesthesia. US-FNA may be risky or not feasible in intrathoracic/substernal thyroid location. Feasibility of aspirating thyroid lesions with EBUS-TBNA has been occasionally reported. We report two patients wherein EBUS-TBNA was utilized for thyroid lesion aspiration and definitive diagnosis. We highlight the utility and safety of EBUS-TBNA in the evaluation of intrathoracic thyroid lesions wherein image-guided percutaneous aspiration may be risky/sometimes impossible to perform. A systematic review of literature has also been performed summarizing and discussing the issues pertaining to EBUS-TBNA of the thyroid gland. PMID:27891005

A land manager's guide to point counts of birds in the Southeast

USGS Publications Warehouse

Hamel, P.B.; Smith, W.P.; Twedt, D.J.; Woehr, J.R.; Morris, E.; Hamilton, R.B.; Cooper, R.J.

1996-01-01

Current widespread concern for the status of neotropical migratory birds has sparked interest in techniques for inventorying and monitoring populations of these and other birds in southeastern forest habitats. The present guide gives detailed instructions for conducting point counts of birds. It further presents a detailed methodology for the design and conduct of inventorial and monitoring surveys based on point counts, including discussion of sample size determination, distribution of counts among habitats, cooperation among neighboring land managers, vegetation sampling, standard data format, and other topics. Appendices provide additional information, making this guide a stand-alone text for managers interested in developing inventories of bird populations on their lands.

Endoscope-guided pneumatic dilation for treatment of esophageal achalasia

PubMed Central

Chuah, Seng-Kee; Wu, Keng-Liang; Hu, Tsung-Hui; Tai, Wei-Chen; Changchien, Chi-Sin

2010-01-01

Pneumatic dilation (PD) is considered to be the first line nonsurgical therapy for achalasia. The principle of the procedure is to weaken the lower esophageal sphincter by tearing its muscle fibers by generating radial force. The endoscope-guided procedure is done without fluoroscopic control. Clinicians usually use a low-compliance balloon such as Rigiflex dilator to perform endoscope-guided PD for the treatment of esophageal achalasia. It has the advantage of determining mucosal injury during the dilation process, so that a repeat endoscopy is not needed to assess the mucosal tearing. Previous studies have shown that endoscope-guided PD is an efficient and safe nonsurgical therapy with results that compare well with other treatment modalities. Although the results may be promising, long-term follow-up is required in the near future. PMID:20101764

Perspectives on leadership: moving out of the corner of our room.

PubMed

Ferguson-Paré, Mary

2011-10-01

Perspectives on leadership developed through a career as a nurse leader are shared, including the author's guiding vision, a valuing of nursing as knowledge work, how to create a learning organization that supports professional practice, and other lessons learned through experience. Readers are urged to find the leadership voice within, be courageous, engage surrounding opportunities, and be guided by their vision of what nursing should be in the future.

Planning, Development, and Change in Bristol Bay: A High School Curriculum. Teacher Guide and Student Text. Unit III: 1991 and Beyond. Unit IV: International Perspective. Revised.

ERIC Educational Resources Information Center

Lipka, Jerry; Willer, Cristy

Written with the broad goal of involving high school students in Bristol Bay, Alaska, in the planning and design of their region's future, this combined teacher guide and student text contains the third and fourth units of a seven-unit curriculum. Unit III covers the terms of the Alaska Native Claims Settlement Act and the complicated issues…

ESHRE's good practice guide for cross-border reproductive care for centers and practitioners.

PubMed

Shenfield, F; Pennings, G; De Mouzon, J; Ferraretti, A P; Goossens, V

2011-07-01

This paper outlines ESHRE's guidance for centers and physicians providing fertility treatment to foreign patients. This guide aims to ensure high-quality and safe assisted reproduction treatment, taking into account the patients, their future child and the interests of third-party collaborators such as gametes donors and surrogates. This is achieved by including considerations of equity, safety, efficiency, effectiveness (including evidence-based care), timeliness and patient centeredness.

Spread Spectrum Receiver Electromagnetic Interference (EMI) Test Guide

NASA Technical Reports Server (NTRS)

Wheeler, Mark L.

1998-01-01

This program consisted of: (1) a study to define appropriate EMI test guidelines and test methods for direct sequence (DS) spread spectrum receivers; and (2) preparation of a written test guide to document the recommended test methods. The scope of this test guide includes: (1) a discussion of generic DS receiver performance characteristics; (2) a summary of S-band TDRSS receiver operation; (3) a discussion of DS receiver EMI susceptibility mechanisms and characteristics; (4) a summary of military standard test guidelines; (5) recommended test approach and methods; and (6) general conclusions and recommendations for future studies in the area of spread spectrum receiver testing.

Recent Science and Engineering Results with the Laser Guidestar Adaptive Optics System at Lick Observatory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gavel, D T; Gates, E; Max, C

2002-10-17

The Lick Observatory laser guide star adaptive optics system has undergone continual improvement and testing as it is being integrated as a facility science instrument on the Shane 3 meter telescope. Both Natural Guide Star (NGS) and Laser Guide Star (LGS) modes are now used in science observing programs. We report on system performance results as derived from data taken on both science and engineering nights and also describe the newly developed on-line techniques for seeing and system performance characterization. We also describe the future enhancements to the Lick system that will enable additional science goals such as long-exposure spectroscopy.

Creating Your Own Case Studies: A Guide for Early Field Experience.

ERIC Educational Resources Information Center

Florio-Ruane, Susan

1990-01-01

A guide for creating case studies is provided for teacher educators to share with students. Suggestions are offered for becoming a participant observer in a classroom. The appendix contains sample appropriate and inappropriate field notes. (SM)

Causes and Effects of Begging Style Involving Children as Guides in Dodoma Municipality, Tanzania: Liability in Basic Education Access

ERIC Educational Resources Information Center

Seni, Abdallah Jacob

2017-01-01

This paper explores the causes and effects of a unique begging style involving children as guides in Dodoma Municipality, Tanzania. The rationale for Dodoma Municipality to be the study location is that the begging phenomenon using children as guides is rampant. The study sample involved 40 respondents, of whom 6 were young carers of visually…

Guide to preparing SAND reports. Revised

DOE Office of Scientific and Technical Information (OSTI.GOV)

Locke, T.K.

1996-04-01

This guide contains basic information needed to produce a SAND report. Its guidelines reflect DOE regulation and Sandia policy. The guide includes basic writing instructions in an annotated sample report; guidance for organization, format, and layout of reports produced by line organizations; and information about conference papers, journal articles, and brochures. The appendixes contain sections on Sandia`s preferred usage, equations, references, copyrights and permissions, and publishing terms.

A Parent's Guide to the ERIC Database. Where To Turn with Your Questions about Schooling. Revised Edition.

ERIC Educational Resources Information Center

Howley, Craig B.; And Others

This guide explains what the Educational Resources Information Center (ERIC) database is and how it can be used by parents to learn more about schooling and parenting. The guide also presents sample records of 55 documents in the ERIC database. The cited resources are particularly relevant to parents' concerns about meeting children's basic needs,…

Neutron optics concept for the materials engineering diffractometer at the ESS

NASA Astrophysics Data System (ADS)

Šaroun, J.; Fenske, J.; Rouijaa, M.; Beran, P.; Navrátil, J.; Lukáš, P.; Schreyer, A.; Strobl, M.

2016-09-01

The Beamline for European Materials Engineering Research (BEER) has been recently proposed to be built at the European Spallation Source (ESS). The presented concept of neutron delivery optics for this instrument addresses the problems of bi-spectral beam extraction from a small moderator, optimization of neutron guides profile for long-range neutron transport and focusing at the sample under various constraints. They include free space before and after the guides, a narrow guide section with gaps for choppers, closing of direct line of sight and cost reduction by optimization of the guides cross-section and coating. A system of slits and exchangeable focusing optics is proposed in order to match various wavelength resolution options provided by the pulse shaping and modulation choppers, which permits to efficiently trade resolution for intensity in a wide range. Simulated performance characteristics such as brilliance transfer ratio are complemented by the analysis of the histories of “useful” neutrons obtained by back tracing neutrons hitting the sample, which helps to optimize some of the neutron guide parameters such as supermirror coating.

IMPROVING TACONITE PROCESSING PLANT EFFICIENCY BY COMPUTER SIMULATION, Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

William M. Bond; Salih Ersayin

2007-03-30

This project involved industrial scale testing of a mineral processing simulator to improve the efficiency of a taconite processing plant, namely the Minorca mine. The Concentrator Modeling Center at the Coleraine Minerals Research Laboratory, University of Minnesota Duluth, enhanced the capabilities of available software, Usim Pac, by developing mathematical models needed for accurate simulation of taconite plants. This project provided funding for this technology to prove itself in the industrial environment. As the first step, data representing existing plant conditions were collected by sampling and sample analysis. Data were then balanced and provided a basis for assessing the efficiency ofmore » individual devices and the plant, and also for performing simulations aimed at improving plant efficiency. Performance evaluation served as a guide in developing alternative process strategies for more efficient production. A large number of computer simulations were then performed to quantify the benefits and effects of implementing these alternative schemes. Modification of makeup ball size was selected as the most feasible option for the target performance improvement. This was combined with replacement of existing hydrocyclones with more efficient ones. After plant implementation of these modifications, plant sampling surveys were carried out to validate findings of the simulation-based study. Plant data showed very good agreement with the simulated data, confirming results of simulation. After the implementation of modifications in the plant, several upstream bottlenecks became visible. Despite these bottlenecks limiting full capacity, concentrator energy improvement of 7% was obtained. Further improvements in energy efficiency are expected in the near future. The success of this project demonstrated the feasibility of a simulation-based approach. Currently, the Center provides simulation-based service to all the iron ore mining companies operating in northern Minnesota, and future proposals are pending with non-taconite mineral processing applications.« less

End-of-life decision making by family caregivers of persons with advanced dementia: A literature review of decision aids.

PubMed

Xie, Bo; Berkley, Amy S; Kwak, Jung; Fleischmann, Kenneth R; Champion, Jane Dimmitt; Koltai, Kolina S

2018-01-01

To investigate existing knowledge in the literature about end-of-life decision making by family caregivers of persons with dementia, focusing on decision aids for caregivers of persons with advanced dementia, and to identify gaps in the literature that can guide future research. A literature review through systematic searches in PubMed, CINAHL Plus with Full Text, and PsycINFO was conducted in February 2018; publications with full text in English and published in the past 10 years were selected in multiple steps. The final sample included five decision aids with predominantly Caucasian participants; three of them had control groups, and three used audiovisual technology in presenting the intervention materials. No other technology was used in any intervention. Existing interventions lacked tailoring of information to caregivers' preferences for different types and amounts of information necessary to make decisions consistent with patients' values. Research is needed in exploring the use of technology in decision aids that could provide tailored information to facilitate caregivers' decision making. More diverse samples are needed.

Real-time optical coherence tomography observation of retinal tissue damage during laser photocoagulation therapy on ex-vivo porcine samples

NASA Astrophysics Data System (ADS)

Steiner, P.; Považay, B.; Stoller, M.; Morgenthaler, P.; Inniger, D.; Arnold, P.; Sznitman, R.; Meier, Ch.

2015-07-01

Retinal laser photocoagulation represents a widely used treatment for retinal pathologies such as diabetic chorioretinopathy or diabetic edema. For effective treatment, an appropriate choice of the treatment energy dose is crucial to prevent excessive tissue damage caused by over-irradiation of the retina. In this manuscript we investigate simultaneous and time-resolved optical coherence tomography for its applicability to provide feedback to the ophthalmologist about the introduced retinal damage during laser photocoagulation. Time-resolved and volumetric optical coherence tomography data of 96 lesions on ex-vivo porcine samples, set with a 577 nm laser prototype and irradiance of between 300 and 8800 W=cm2 were analyzed. Time-resolved scans were compared to volumetric scans of the lesion and correlated with ophthalmoscopic visibility. Lastly, image parameters extracted from optical coherence tomography Mscans, suitable for lesion classification were identified. Results presented in this work support the hypothesis that simultaneous optical coherence tomography provides valuable information about the extent of retinal tissue damage and may be used to guide retinal laser photocoagulation in the future.

Developing an intervention to address physical activity barriers for African–American women in the deep south (USA)

PubMed Central

Pekmezi, Dori; Marcus, Bess; Meneses, Karen; Baskin, Monica L; Ard, Jamy D; Martin, Michelle Y; Adams, Natasia; Robinson, Cody; Demark-Wahnefried, Wendy

2013-01-01

Aim To address high rates of inactivity and related chronic diseases among African–American women. Materials & methods Eleven focus groups on physical activity barriers for African–American women in the deep south (USA) were conducted (n = 56). Feedback guided an intervention development process. The resulting Home-Based Individually Tailored Physical Activity Print intervention was vetted with the target population in a 1-month, single arm, pre–post test demonstration trial (n = 10). Results Retention was high (90%). Intent-to-treat analyses indicated increases in motivational readiness for physical activity (70% of sample) and physical activity (7-day Physical Activity Recall) from baseline (mean: 89.5 min/week, standard deviation: 61.17) to 1 month (mean: 155 min/week, standard deviation: 100.86). Small improvements in fitness (6-Min Walk Test), weight and psychosocial process measures were also found. Conclusion Preliminary findings show promise and call for future randomized controlled trials with larger samples to determine efficacy. Such low-cost, high-reach approaches to promoting physical activity have great potential for addressing health disparities and benefiting public health. PMID:23638785

Replication and extension of the dual pathway model of disordered eating: The role of fear of negative evaluation, suggestibility, rumination, and self-compassion.

PubMed

Maraldo, Toni M; Zhou, Wanni; Dowling, Jessica; Vander Wal, Jillon S

2016-12-01

The dual pathway model, a theoretical model of eating disorder development, suggests that thin ideal internalization leads to body dissatisfaction which leads to disordered eating via the dual pathways of negative affect and dietary restraint. While the dual pathway model has been a valuable guide for eating disorder prevention, greater knowledge of characteristics that predict thin ideal internalization is needed. The present study replicated and extended the dual pathway model by considering the addition of fear of negative evaluation, suggestibility, rumination, and self-compassion in a sample of community women and female university students. Results showed that fear of negative evaluation and suggestibility predicted thin ideal internalization whereas rumination and self-compassion (inversely) predicted body dissatisfaction. Negative affect was predicted by fear of negative evaluation, rumination, and self-compassion (inversely). The extended model fit the data well in both samples. Analogue and longitudinal study of these constructs is warranted in future research. Copyright © 2016 Elsevier Ltd. All rights reserved.

Developing an intervention to address physical activity barriers for African-American women in the deep south (USA).

PubMed

Pekmezi, Dori; Marcus, Bess; Meneses, Karen; Baskin, Monica L; Ard, Jamy D; Martin, Michelle Y; Adams, Natasia; Robinson, Cody; Demark-Wahnefried, Wendy

2013-05-01

To address high rates of inactivity and related chronic diseases among African-American women. Eleven focus groups on physical activity barriers for African-American women in the deep south (USA) were conducted (n = 56). Feedback guided an intervention development process. The resulting Home-Based Individually Tailored Physical Activity Print intervention was vetted with the target population in a 1-month, single arm, pre-post test demonstration trial (n = 10). Retention was high (90%). Intent-to-treat analyses indicated increases in motivational readiness for physical activity (70% of sample) and physical activity (7-day Physical Activity Recall) from baseline (mean: 89.5 min/week, standard deviation: 61.17) to 1 month (mean: 155 min/week, standard deviation: 100.86). Small improvements in fitness (6-Min Walk Test), weight and psychosocial process measures were also found. Preliminary findings show promise and call for future randomized controlled trials with larger samples to determine efficacy. Such low-cost, high-reach approaches to promoting physical activity have great potential for addressing health disparities and benefiting public health.

NASA's Student Airborne Research Program (2009-2013)

NASA Astrophysics Data System (ADS)

Schaller, E. L.; Shetter, R. E.

2013-12-01

The NASA Student Airborne Research Program (SARP) is a unique summer internship program for rising senior undergraduates majoring in any of the STEM disciplines. SARP participants acquire hands-on research experience in all aspects of an airborne research campaign, including flying onboard an major NASA resource used for studying Earth system processes. In summer 2013, thirty-two participants worked in four interdisciplinary teams to study surface, atmospheric, and oceanographic processes. Participants assisted in the operation of instruments onboard the NASA DC-8 aircraft where they sampled and measured atmospheric gases and imaged land and water surfaces in multiple spectral bands. Along with airborne data collection, students participated in taking measurements at field sites. Mission faculty and research mentors helped to guide participants through instrument operation, sample analysis, and data reduction. Over the eight-week program, each student developed an individual research project from the data collected and delivered a conference-style final presentation on his/her results. Several students will present the results of their research in science sessions at this meeting. We will discuss the results and effectiveness of the program over the past five summers and plans for the future.

Individual, social and community-level predictors of wellbeing in a US sample of transgender and gender non-conforming individuals.

PubMed

Stanton, Megan C; Ali, Samira; Chaudhuri, Sambuddha

2017-01-01

In the last decade, increased attention has been paid to the physical and mental health needs of transgender and gender non-conforming individuals. However, despite this surge of research, scant literature addresses factors associated with wellbeing among members of this population. Using data from the US Social Justice Sexuality Survey, this study examines predictors of wellbeing in a sample of transgender and gender non-conforming individuals. Results indicate that higher levels of wellbeing are predicted by education, older age and a greater sense of connectedness to the lesbian, gay, bisexual and transgender community. Additionally, although health insurance did not have a significant impact on wellbeing, increased general health was associated with greater wellbeing, as was perceived comfort of the healthcare provider regarding the respondent's sexual identity. These findings can inform multi-level intervention with transgender and gender non-conforming persons to promote their wellbeing, as well as guide policies and practices around healthcare provider training. Future research should further examine the interconnected predictors of wellbeing among members of this population.

School Auditoriums.

ERIC Educational Resources Information Center

American School Board Journal, 1965

1965-01-01

Auditoriums of the future, divisible auditoriums, economic advantages of multi-service space and auditorium location are discussed. Also presented are guides for buying and selecting seating, state equipment, portable stages, and stage lighting. (RK)

Sample Size in Qualitative Interview Studies: Guided by Information Power.

PubMed

Malterud, Kirsti; Siersma, Volkert Dirk; Guassora, Ann Dorrit

2015-11-27

Sample sizes must be ascertained in qualitative studies like in quantitative studies but not by the same means. The prevailing concept for sample size in qualitative studies is "saturation." Saturation is closely tied to a specific methodology, and the term is inconsistently applied. We propose the concept "information power" to guide adequate sample size for qualitative studies. Information power indicates that the more information the sample holds, relevant for the actual study, the lower amount of participants is needed. We suggest that the size of a sample with sufficient information power depends on (a) the aim of the study, (b) sample specificity, (c) use of established theory, (d) quality of dialogue, and (e) analysis strategy. We present a model where these elements of information and their relevant dimensions are related to information power. Application of this model in the planning and during data collection of a qualitative study is discussed. © The Author(s) 2015.

Optimizing the triple-axis spectrometer PANDA at the MLZ for small samples and complex sample environment conditions

NASA Astrophysics Data System (ADS)

Utschick, C.; Skoulatos, M.; Schneidewind, A.; Böni, P.

2016-11-01

The cold-neutron triple-axis spectrometer PANDA at the neutron source FRM II has been serving an international user community studying condensed matter physics problems. We report on a new setup, improving the signal-to-noise ratio for small samples and pressure cell setups. Analytical and numerical Monte Carlo methods are used for the optimization of elliptic and parabolic focusing guides. They are placed between the monochromator and sample positions, and the flux at the sample is compared to the one achieved by standard monochromator focusing techniques. A 25 times smaller spot size is achieved, associated with a factor of 2 increased intensity, within the same divergence limits, ± 2 ° . This optional neutron focusing guide shall establish a top-class spectrometer for studying novel exotic properties of matter in combination with more stringent sample environment conditions such as extreme pressures associated with small sample sizes.

A pilot study to understand feasibility and acceptability of stool and cord blood sample collection for a large-scale longitudinal birth cohort.

PubMed

Bailey, S R; Townsend, C L; Dent, H; Mallet, C; Tsaliki, E; Riley, E M; Noursadeghi, M; Lawley, T D; Rodger, A J; Brocklehurst, P; Field, N

2017-12-28

Few data are available to guide biological sample collection around the time of birth for large-scale birth cohorts. We are designing a large UK birth cohort to investigate the role of infection and the developing immune system in determining future health and disease. We undertook a pilot to develop methodology for the main study, gain practical experience of collecting samples, and understand the acceptability of sample collection to women in late pregnancy. Between February-July 2014, we piloted the feasibility and acceptability of collecting maternal stool, baby stool and cord blood samples from participants recruited at prolonged pregnancy and planned pre-labour caesarean section clinics at University College London Hospital. Participating women were asked to complete acceptability questionnaires. Overall, 265 women were approached and 171 (65%) participated, with ≥1 sample collected from 113 women or their baby (66%). Women had a mean age of 34 years, were primarily of white ethnicity (130/166, 78%), and half were nulliparous (86/169, 51%). Women undergoing planned pre-labour caesarean section were more likely than those who delivered vaginally to provide ≥1 sample (98% vs 54%), but less likely to provide maternal stool (10% vs 43%). Pre-sample questionnaires were completed by 110/171 women (64%). Most women reported feeling comfortable with samples being collected from their baby (<10% uncomfortable), but were less comfortable about their own stool (19% uncomfortable) or a vaginal swab (24% uncomfortable). It is possible to collect a range of biological samples from women around the time of delivery, and this was acceptable for most women. These data inform study design and protocol development for large-scale birth cohorts.

Preparing for the Future: A Student Transition Handbook. Documentation of a Collaborative Transition Planning System: West End SELPA.

ERIC Educational Resources Information Center

Cahill, Deborah, Comp.; And Others

This handbook acquaints special needs students with programs and opportunities available to help them make the transition from school to working. The guide helps students identify their personal strengths, identify goals for the future, determine skills needed to reach those goals, and determine help needed from others. The body of the guide…

Opening Windows Onto the Future: Theory of the Governor's School of North Carolina.

ERIC Educational Resources Information Center

Lewis, H. Michael

Presented is the curriculum theory designed for 400 gifted boys and girls, from rising junior and senior classes in high school, who attend the 8-week summer Governor's School (GS) of North Carolina. The main aim of the GS is given to be inspiring and guiding future leaders by providing opportunities for special aptitude, general conceptual, and…

America, the Soviets and Nuclear Arms: Looking to the Future. Teacher's Resource Book.

ERIC Educational Resources Information Center

Berger, Karl; And Others

This curriculum project focuses on U.S.-Soviet relations and the choices that U.S. citizens face today in addressing the Soviet Union and the threat of nuclear war. This book is intended as a resource guide to accompany a 22-minute video presentation and student text that are part of the "Four Futures" curriculum. The resource book…

Is there a future for GMOs?

PubMed

Beringer, J E

2000-04-01

Despite strict regulation and a clean safety record, research and development of genetically modified (GM) crops and other organisms has been confronted with tremendous public hostility. Why has this happened, and how can scientists try to guide the debate into more rational channels? The answers may determine the future of GM technology and our ability to provide for a growing world population.

Percutaneous CT-guided sacroiliac joint sampling for infection: aspiration, biopsy, and technique.

PubMed

Knipp, David; Simeone, F Joseph; Nelson, Sandra B; Huang, Ambrose J; Chang, Connie Y

2018-04-01

To evaluate methods of CT-guided sacroiliac joint sampling in patients with suspected infection. All CT-guided sacroiliac joint sampling procedures for suspected infection were reviewed for sampling type (aspiration, lavage aspiration, biopsy), microbiology results, and clinical and imaging follow-up. The primary gold standard was anatomic pathology. If pathology was not available, then positive blood culture with the same organism as SIJ sampling, imaging and clinical follow-up, or clinical follow-up only were used. Anterior and posterior joint distention was evaluated by MRI within 7 days of the procedure. A total of 34 patients (age 39 ± 20 (range, 6-75) years; 21 F, 13 M) were included. Aspiration samples only were obtained in 13/34 (38%) cases, biopsy samples only in 9/34 (26%) cases, and both samples in 12/34 (35%) cases. There was an overall 54% sensitivity and 86% specificity. For the aspiration samples, sensitivity and specificity were 60 and 81%, respectively, compared to 45 and 90% for the biopsy samples. In cases with both samples, biopsy did not add additional microbial information. Seventeen (17/34, 50%) patients had an MRI. The anterior joint was more distended than the posterior joint in 15/17 (88%) of patients, and this difference was significant (P = 0.0003). All of these 17 patients had an attempted aspiration by a posterior approach; 6/17 (35%) resulted in a successful aspiration. Aspiration of the sacroiliac joint has a higher sensitivity than biopsy and should always be attempted first. MRI may be helpful for procedure planning.

Toward optical guidance during endoscopic ultrasound-guided fine needle aspirations of pancreatic masses using single fiber reflectance spectroscopy: a feasibility study

NASA Astrophysics Data System (ADS)

Stegehuis, Paulien L.; Boogerd, Leonora S. F.; Inderson, Akin; Veenendaal, Roeland A.; van Gerven, P.; Bonsing, Bert A.; Sven Mieog, J.; Amelink, Arjen; Veselic, Maud; Morreau, Hans; van de Velde, Cornelis J. H.; Lelieveldt, Boudewijn P. F.; Dijkstra, Jouke; Robinson, Dominic J.; Vahrmeijer, Alexander L.

2017-02-01

Endoscopic ultrasound-guided fine needle aspirations (EUS-FNA) of pancreatic masses suffer from sample errors and low-negative predictive values. Fiber-optic spectroscopy in the visible to near-infrared wavelength spectrum can noninvasively extract physiological parameters from tissue and has the potential to guide the sampling process and reduce sample errors. We assessed the feasibility of single fiber (SF) reflectance spectroscopy measurements during EUS-FNA of pancreatic masses and its ability to distinguish benign from malignant pancreatic tissue. A single optical fiber was placed inside a 19-gauge biopsy needle during EUS-FNA and at least three reflectance measurements were taken prior to FNA. Spectroscopy measurements did not cause any related adverse events and prolonged procedure time with ˜5 min. An accurate correlation between spectroscopy measurements and cytology could be made in nine patients (three benign and six malignant). The oxygen saturation and bilirubin concentration were significantly higher in benign tissue compared with malignant tissue (55% versus 21%, p=0.038; 166 μmol/L versus 17 μmol/L, p=0.039, respectively). To conclude, incorporation of SF spectroscopy during EUS-FNA was feasible, safe, and relatively quick to perform. The optical properties of benign and malignant pancreatic tissue are different, implying that SF spectroscopy can potentially guide the FNA sampling.

Deconvolution imaging of weak reflective pipe defects using guided-wave signals captured by a scanning receiver.

PubMed

Sun, Zeqing; Sun, Anyu; Ju, Bing-Feng

2017-02-01

Guided-wave echoes from weak reflective pipe defects are usually interfered by coherent noise and difficult to interpret. In this paper, a deconvolution imaging method is proposed to reconstruct defect images from synthetically focused guided-wave signals, with enhanced axial resolution. A compact transducer, circumferentially scanning around the pipe, is used to receive guided-wave echoes from discontinuities at a distance. This method achieves a higher circumferential sampling density than arrayed transducers-up to 72 sampling spots per lap for a pipe with a diameter of 180 mm. A noise suppression technique is used to enhance the signal-to-noise ratio. The enhancement in both signal-to-noise ratio and axial resolution of the method is experimentally validated by the detection of two kinds of artificial defects: a pitting defect of 5 mm in diameter and 0.9 mm in maximum depth, and iron pieces attached to the pipe surface. A reconstructed image of the pitting defect is obtained with a 5.87 dB signal-to-noise ratio. It is revealed that a high circumferential sampling density is important for the enhancement of the inspection sensitivity, by comparing the images reconstructed with different down-sampling ratios. A modified full width at half maximum is used as the criterion to evaluate the circumferential extent of the region where iron pieces are attached, which is applicable for defects with inhomogeneous reflection intensity.

Physiological and behavioral indices of emotion dysregulation as predictors of outcome from cognitive behavioral therapy and acceptance and commitment therapy for anxiety.

PubMed

Davies, Carolyn D; Niles, Andrea N; Pittig, Andre; Arch, Joanna J; Craske, Michelle G

2015-03-01

Identifying for whom and under what conditions a treatment is most effective is an essential step toward personalized medicine. The current study examined pre-treatment physiological and behavioral variables as predictors and moderators of outcome in a randomized clinical trial comparing cognitive behavioral therapy (CBT) and acceptance and commitment therapy (ACT) for anxiety disorders. Sixty individuals with a DSM-IV defined principal anxiety disorder completed 12 sessions of either CBT or ACT. Baseline physiological and behavioral variables were measured prior to entering treatment. Self-reported anxiety symptoms were assessed at pre-treatment, post-treatment, and 6- and 12-month follow-up from baseline. Higher pre-treatment heart rate variability was associated with worse outcome across ACT and CBT. ACT outperformed CBT for individuals with high behavioral avoidance. Subjective anxiety levels during laboratory tasks did not predict or moderate treatment outcome. Due to small sample sizes of each disorder, disorder-specific predictors were not tested. Future research should examine these predictors in larger samples and across other outcome variables. Lower heart rate variability was identified as a prognostic indicator of overall outcome, whereas high behavioral avoidance was identified as a prescriptive indicator of superior outcome from ACT versus CBT. Investigation of pre-treatment physiological and behavioral variables as predictors and moderators of outcome may help guide future treatment-matching efforts. Copyright © 2014 Elsevier Ltd. All rights reserved.

Review of child maltreatment in immigrant and refugee families.

PubMed

LeBrun, Annie; Hassan, Ghayda; Boivin, Mylène; Fraser, Sarah-Louise; Dufour, Sarah; Lavergne, Chantal

2016-03-14

Study results on child maltreatment based on general population samples cannot be extrapolated with confidence to vulnerable immigrant or refugee families because of the specific characteristics and needs of these families. The aims of this paper are 1) to conduct an evidence review of the prevalence, risk factors and protective factors for child maltreatment in immigrant and refugee populations, and 2) to integrate the evidence in an analytical ecosystemic framework that would guide future research. We used a 14-step process based on guidelines from Preferred Reporting Items for Systematic Reviews and Meta-Analyses and the Canadian Collaboration for Immigrant and Refugee Health. We searched major databases from "the oldest date available to July 2014". The eligibility criteria for paper selection included qualitative or quantitative methodologies; papers written in English or French; papers that describe, assess or review prevalence, risk and protection factors for child maltreatment; and a studied population of immigrants or refugees. Twenty-four articles met the criteria for eligibility. The results do not provide evidence that immigrant or refugee children are at higher risk of child maltreatment. However, recently settled immigrants and refugees experience specific risk factors related to their immigration status and to the challenges of settlement in a new country, which may result in high risk of maltreatment. Future research must incorporate more immigrant and refugee samples as well as examine, within an ecosystemic framework, the interaction between migratory and cultural factors with regard to the prevalence, consequences and treatment of child maltreatment for the targeted groups.

Expert opinion regarding the preparation of entry-level physiotherapists for primary healthcare practice, examined using Biggs 3P's model of teaching learning.

PubMed

McMahon, Sinead; O'Donoghue, Grainne; Doody, Catherine; O'Neill, Geraldine; Cusack, Tara

2016-05-01

The scope of contemporary physiotherapy practice is a critical factor in determining the appropriate educational preparation for physiotherapists now and into the future. The world-wide shift from secondary to primary healthcare has, and is, continuing to result in new and different ways of working. It is crucial that curricular changes reflect these developments. In this study a qualitative approach using Biggs 3P's - Pressage, Process and Product model to discuss curriculum design. The aim of the study was to explore the perspectives of both national and international physiotherapy educators/practitioners in primary healthcare, on the key elements required in physiotherapy education programmes to prepare future primary healthcare practitioners. Snowball sampling was used to identify experts in education and/or primary healthcare practice. Semi-structured interviews were conducted using an interview guide based on the Biggs 3P's model. Twelve participants were recruited from Ireland (n = 2), the UK (n = 4), Canada (n = 3), New Zealand (n = 2) and Australia (n = 1) using snowball sampling. Interviews were analysed using thematic analysis. Themes identified included; understanding the philosophy of physiotherapy practice, cultural competence, inter-disciplinary team working and communication skills. Contextual factors and teaching and learning strategies were discussed. There is an urgent need for physiotherapy education programmes to adopt the concept of primary healthcare as the basis for the physiotherapy curriculum and illuminate key components for consideration.

The associations between blood lipids and the Food Guide Pyramid: findings from the Third National Health and Nutrition Examination Survey.

PubMed

Tande, Desiree L; Hotchkiss, Larry; Cotugna, Nancy

2004-04-01

Dietary recommendations are based on nutrients, foods, and food groups, but the relationship between the Food Guide Pyramid (FGP) food groups and serum lipids has not been studied. NHANES III data were obtained for US adults who met the following criteria: aged 20-59 years, reliable participant, and typical 24-h recall. We examined whether serum lipids (serum total cholesterol (STC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triacylglycerol) were related to FGP food group intake (dairy, fruit, grain, meat, and vegetable). A sample of 9111 participants qualified for this analysis. Fruit intakes were inversely related to STC, HDL-C, and LDL-C (P = 0.012, P = 0.001, and P = 0.014, respectively) and directly related to triacylglycerol levels (P = 0.003). Grain intake was inversely associated with both STC and HDL-C (P = 0.020 and P = 0.000). Dairy and meat intakes were directly related to LDL-C (P = 0.026 and P = 0.020). Food groups are related to serum lipids. Universal definitions for food groups are needed in research and nutrition education. Studying the relationships between food groups and serum lipids is important for future dietary recommendations related to serum lipids.

Guided in Situ Polymerization of MEH-PPV in Mesoporous Titania Photoanodes.

PubMed

Minar, Norma K; Docampo, Pablo; Fattakhova-Rohlfing, Dina; Bein, Thomas

2015-05-20

Incorporation of conjugated polymers into porous metal oxide networks is a challenging task, which is being pursued via many different approaches. We have developed the guided in situ polymerization of poly(2-methoxy-5-(2'-ethylhexyloxy)-p-phenylenevinylene) (MEH-PPV) in porous titania films by means of surface functionalization. The controlled polymerization via the Gilch route was induced by an alkoxide base and by increasing the temperature. The selected and specially designed surface-functionalizing linker molecules mimic the monomer or its activated form, respectively. In this way, we drastically enhanced the amount of MEH-PPV incorporated into the porous titania phase compared to nonfunctionalized samples by a factor of 6. Additionally, photovoltaic measurements were performed. The devices show shunting or series resistance limitations, depending on the surface functionalization prior to in situ polymerization of MEH-PPV. We suggest that the reason for this behavior can be found in the orientation of the grown polymer chains with respect to the titania surface. Therefore, the geometry of the anchoring via the linker molecules is relevant for exploiting the full electronic potential of the conjugated polymer in the resulting hybrid composite. This observation will help to design future synthesis methods for new hybrid materials from conjugated polymers and n-type semiconductors to take full advantage of favorable electronic interactions between the two phases.

Towards interruption of schistosomiasis transmission in sub-Saharan Africa: developing an appropriate environmental surveillance framework to guide and to support 'end game' interventions.

PubMed

Stothard, J Russell; Campbell, Suzy J; Osei-Atweneboana, Mike Y; Durant, Timothy; Stanton, Michelle C; Biritwum, Nana-Kwadwo; Rollinson, David; Ombede, Dieudonné R Eloundou; Tchuem-Tchuenté, Louis-Albert

2017-01-14

Schistosomiasis is a waterborne parasitic disease in sub-Saharan Africa, particularly common in rural populations living in impoverished conditions. With the scale-up of preventive chemotherapy, national campaigns will transition from morbidity- to transmission-focused interventions thus formal investigation of actual or expected declines in environmental transmission is needed as 'end game' scenarios arise. Surprisingly, there are no international or national guidelines to do so in sub-Saharan Africa. Our article therefore provides an introduction to key practicalities and pitfalls in the development of an appropriate environmental surveillance framework. In this context, we discuss how strategies need to be adapted and tailored to the local level to better guide and support future interventions through this transition. As detection of egg-patent infection in people becomes rare, careful sampling of schistosome larvae in freshwater and in aquatic snails with robust species-specific DNA assays will be required. Appropriate metrics, derived from observed prevalence(s) as compared with predetermined thresholds, could each provide a clearer insight into contamination- and exposure-related dynamics. Application could be twofold, first to certify areas currently free from schistosomiasis transmission or second to red-flag recalcitrant locations where extra effort or alternative interventions are needed.

Direct comparisons of Illumina vs. Roche 454 sequencing technologies on the same microbial community DNA sample.

PubMed

Luo, Chengwei; Tsementzi, Despina; Kyrpides, Nikos; Read, Timothy; Konstantinidis, Konstantinos T

2012-01-01

Next-generation sequencing (NGS) is commonly used in metagenomic studies of complex microbial communities but whether or not different NGS platforms recover the same diversity from a sample and their assembled sequences are of comparable quality remain unclear. We compared the two most frequently used platforms, the Roche 454 FLX Titanium and the Illumina Genome Analyzer (GA) II, on the same DNA sample obtained from a complex freshwater planktonic community. Despite the substantial differences in read length and sequencing protocols, the platforms provided a comparable view of the community sampled. For instance, derived assemblies overlapped in ~90% of their total sequences and in situ abundances of genes and genotypes (estimated based on sequence coverage) correlated highly between the two platforms (R(2)>0.9). Evaluation of base-call error, frameshift frequency, and contig length suggested that Illumina offered equivalent, if not better, assemblies than Roche 454. The results from metagenomic samples were further validated against DNA samples of eighteen isolate genomes, which showed a range of genome sizes and G+C% content. We also provide quantitative estimates of the errors in gene and contig sequences assembled from datasets characterized by different levels of complexity and G+C% content. For instance, we noted that homopolymer-associated, single-base errors affected ~1% of the protein sequences recovered in Illumina contigs of 10× coverage and 50% G+C; this frequency increased to ~3% when non-homopolymer errors were also considered. Collectively, our results should serve as a useful practical guide for choosing proper sampling strategies and data possessing protocols for future metagenomic studies.

Gender-Specific Differences in the Relationship between Autobiographical Memory and Intertemporal Choice in Older Adults

PubMed Central

Seinstra, Maayke; Grzymek, Katharina; Kalenscher, Tobias

2015-01-01

As the population of older adults grows, their economic choices will have increasing impact on society. Research on the effects of aging on intertemporal decisions shows inconsistent, often opposing results, indicating that yet unexplored factors might play an essential role in guiding one's choices. Recent studies suggest that episodic future thinking, which is based on the same neural network involved in episodic memory functions, leads to reductions in discounting of future rewards. As episodic memory functioning declines with normal aging, but to greatly variable degrees, individual differences in delay discounting might be due to individual differences in the vitality of this memory system in older adults. We investigated this hypothesis, using a sample of healthy older adults who completed an intertemporal choice task as well as two episodic memory tasks. We found no clear evidence for a relationship between episodic memory performance and delay discounting in older adults. However, when additionally considering gender differences, we found an interaction effect of gender and autobiographical memory on delay discounting: while men with higher memory scores showed less delay discounting, women with higher memory scores tended to discount the future more. We speculate that this gender effect might stem from the gender-specific use of different modal representation formats (i.e. temporal or visual) during assessment of intertemporal choice options. PMID:26335426

Future Field Programmable Gate Array (FPGA) Design Methodologies and Tool Flows

DTIC Science & Technology

2008-07-01

a) that the results are accepted by users, vendors, … and (b) that they can quantitatively explain HPC rules of thumb such as: “OpenMP is easier...in productivity that were demonstrated by traditional software systems. Using advances in software productivity as a guide , we have identified three...of this study we developed a productivity model to guide our investigation (14). Models have limitations and the model we propose is no exception

Technology Transfer Policy Applied to the U.S. Army Military History Institute Collection.

DTIC Science & Technology

1998-04-15

from the OSHA GUIDE data files. Computer software does not include computer database or computer software documentation. 1.10 "COMPUTER SOFTWARE...advising all current or future users of the OSHA GUIDE of its availability through XYZ COMPANY 32 CBks Memo 870-2 Appendix E Terms Cooperative... Malaysia No. PI920163 Mexico No. 925240 Philippines No. 44927 PCT US92/07556 Australia No. 26447/92 Canada No. 2,119,006 Czech Republic No. PV

Soldier Quality of Life (Operational) and Readiness at Contingency Base Camps: Insights From Qualitative Interviews

DTIC Science & Technology

2017-03-13

camps and Soldier/small unit readiness to guide the development of a quantitative readiness survey . • During structured interviews, 31 Soldiers...camps and Soldier/small unit readiness to guide the development of a quantitative readiness survey . 11UNCLASSIFIED Click to hear quote Methods...We were rock stars.” 60UNCLASSIFIED • These data are driving the selection of attributes for a future quantitative survey of the link between QoL

The future of U.S./International life sciences cooperation for Space Shuttle and beyond - A guide for the young professional

NASA Technical Reports Server (NTRS)

Garshnek, V.; Davies, P.; Ballard, R.

1992-01-01

Current international capabilities in the space life sciences/technology areas are reviewed focusing on the cooperative potential of the international community as applied to advanced Shuttle/Spacelab flights. The review of the international experience base and mutual cooperative benefits of the United States and international partners presented in the paper provides a guide to the young professional in planning for a space life sciences career.

Endodontic applications of 3D printing.

PubMed

Anderson, J; Wealleans, J; Ray, J

2018-02-27

Computer-aided design (CAD) and computer-aided manufacturing (CAM) technologies can leverage cone beam computed tomography data for production of objects used in surgical and nonsurgical endodontics and in educational settings. The aim of this article was to review all current applications of 3D printing in endodontics and to speculate upon future directions for research and clinical use within the specialty. A literature search of PubMed, Ovid and Scopus was conducted using the following terms: stereolithography, 3D printing, computer aided rapid prototyping, surgical guide, guided endodontic surgery, guided endodontic access, additive manufacturing, rapid prototyping, autotransplantation rapid prototyping, CAD, CAM. Inclusion criteria were articles in the English language documenting endodontic applications of 3D printing. Fifty-one articles met inclusion criteria and were utilized. The endodontic literature on 3D printing is generally limited to case reports and pre-clinical studies. Documented solutions to endodontic challenges include: guided access with pulp canal obliteration, applications in autotransplantation, pre-surgical planning and educational modelling and accurate location of osteotomy perforation sites. Acquisition of technical expertise and equipment within endodontic practices present formidable obstacles to widespread deployment within the endodontic specialty. As knowledge advances, endodontic postgraduate programmes should consider implementing 3D printing into their curriculums. Future research directions should include clinical outcomes assessments of treatments employing 3D printed objects. Published 2018. This article is a U.S. Government work and is in the public domain in the USA.

Through a glass darkly: economics and personalised medicine.

PubMed

Haycox, Alan; Pirmohamed, Munir; McLeod, Claire; Houten, Rachel; Richards, Sarah

2014-11-01

Personalised medicine and pharmacogenetic-test-guided treatment strategies will be of increasing importance in the future, both in terms of healthcare provision and evaluation. It is well recognised that significant variability exists in the response of patients to drugs resulting from genetic or biological variations; however, we are only now gradually becoming aware of the complexities involved. Enormous variability occurs in the risk-benefit ratio that will be experienced by each individual patient as a consequence of their overall genetic make-up. Although not a panacea, enhanced scientific knowledge of the genetic basis for such variability offers the potential for a more 'tailored' approach to prescribing in the future, making it more closely attuned to the needs of the individual patient. Such 'personalised' medicine has the potential to revolutionise care provision in a manner that provides a range of challenges to current structures and processes of 'conventional' healthcare delivery. The aim of this paper is to outline such challenges and analyse potential ways in which they may be addressed in the future. It provides non-expert readers with a non-technical case study of the complexities inherent in the evaluation of a pharmacogenetic-test-guided treatment strategy from a health economic perspective. Wherever possible, technical issues have been minimised; however, references are provided for readers who wish to enhance their knowledge of the pharmacological basis of the case study of cytochrome P450 test-guided treatment. The case study aims simply to illustrate the approach and difficulties encountered in the health economic evaluation of complex pharmacogenetic technologies. Such technologies present a range of new and complex issues which have crucial implications for health economists attempting to obtain an accurate assessment of the 'value' of the technology in clinical practice in an array of patient subgroups. Personalised medicine is the future and this paper highlights how pharmaceutical manufacturers, clinicians, regulators and other stakeholders must all play their part in the inevitable and accelerating move into this complex and uncertain future.

The Prompt Book for...Teaching the Art of Speech and Drama To Children: A Resource Guide for Teachers of Children in the Art of Speech and Drama.

ERIC Educational Resources Information Center

Dugger, Anita; And Others

Providing for individual differences in ability, interest, and cultural values among students, this guide contains resources, goals, objectives, sample lesson plans, and activities for teaching speech and drama to elementary school students. The first section of the guide offers advice on the organization of a speech arts curriculum, approaches to…

Health Grades K-6. Skills-Based Scope and Sequence Guide. Target Skills and Sample Assessment Methods.

ERIC Educational Resources Information Center

Williamson, Anne; Beegle, Jenny; Gilbert, Lisa; Safaii, SeAnne; Eck, Paul; Remaley, Renea; Hasselquist, Claudia; Hatch, Kathy C.; Thompson, Kay

This guide is organized around a suggested list of health skills that all students should know and be able to do at each grade level from kindergarten through grade 6. The guide will help provide parents, teachers, and students with knowledge of what is being taught in a logical scope and sequence by grade level. It is designed to help build a…

SWMM-CAT User’s Guide

EPA Science Inventory

The Storm Water Management Model Climate Adjustment Tool (SWMM-CAT) is a simple to use software utility that allows future climate change projections to be incorporated into the Storm Water Management Model (SWMM).

How to Handle Speciose Clades? Mass Taxon-Sampling as a Strategy towards Illuminating the Natural History of Campanula (Campanuloideae)

PubMed Central

Mansion, Guilhem; Parolly, Gerald; Crowl, Andrew A.; Mavrodiev, Evgeny; Cellinese, Nico; Oganesian, Marine; Fraunhofer, Katharina; Kamari, Georgia; Phitos, Dimitrios; Haberle, Rosemarie; Akaydin, Galip; Ikinci, Nursel; Raus, Thomas; Borsch, Thomas

2012-01-01

Background Speciose clades usually harbor species with a broad spectrum of adaptive strategies and complex distribution patterns, and thus constitute ideal systems to disentangle biotic and abiotic causes underlying species diversification. The delimitation of such study systems to test evolutionary hypotheses is difficult because they often rely on artificial genus concepts as starting points. One of the most prominent examples is the bellflower genus Campanula with some 420 species, but up to 600 species when including all lineages to which Campanula is paraphyletic. We generated a large alignment of petD group II intron sequences to include more than 70% of described species as a reference. By comparison with partial data sets we could then assess the impact of selective taxon sampling strategies on phylogenetic reconstruction and subsequent evolutionary conclusions. Methodology/Principal Findings Phylogenetic analyses based on maximum parsimony (PAUP, PRAP), Bayesian inference (MrBayes), and maximum likelihood (RAxML) were first carried out on the large reference data set (D680). Parameters including tree topology, branch support, and age estimates, were then compared to those obtained from smaller data sets resulting from “classification-guided” (D088) and “phylogeny-guided sampling” (D101). Analyses of D088 failed to fully recover the phylogenetic diversity in Campanula, whereas D101 inferred significantly different branch support and age estimates. Conclusions/Significance A short genomic region with high phylogenetic utility allowed us to easily generate a comprehensive phylogenetic framework for the speciose Campanula clade. Our approach recovered 17 well-supported and circumscribed sub-lineages. Knowing these will be instrumental for developing more specific evolutionary hypotheses and guide future research, we highlight the predictive value of a mass taxon-sampling strategy as a first essential step towards illuminating the detailed evolutionary history of diverse clades. PMID:23209646

A randomised crossover study to compare the cross-sectional and longitudinal approaches to ultrasound-guided peripheral venepuncture in a model.

PubMed

Griffiths, James; Carnegie, Amadeus; Kendall, Richard; Madan, Rajeev

2017-12-01

Ultrasound-guided peripheral intravenous access may present an alternative to central or intraosseous access in patients with difficult peripheral veins. Using venepuncture of a phantom model as a proxy, we investigated whether novice ultrasound users should adopt a cross-sectional or longitudinal approach when learning to access peripheral veins under ultrasound guidance. This result would inform the development of a structured training method for this procedure. We conducted a randomised controlled trial of 30 medical students. Subjects received 35 min of training, then attempted to aspirate 1 ml of synthetic blood from a deep vein in a training model under ultrasound guidance. Subjects attempted both the cross-sectional and longitudinal approaches. Group 1 used cross-sectional first, followed by longitudinal. Group 2 used longitudinal first, then cross-sectional. We measured the time from first puncture of the model's skin to aspiration of fluid, and the number of attempts required. Subjects also reported difficulty ratings for each approach. Paired sample t-tests were used for statistical analysis. The mean number of attempts was 1.13 using the cross-sectional approach, compared with 1.30 using the longitudinal approach (p = 0.17). Mean time to aspiration of fluid was 45.1 s using the cross-sectional approach and 52.8 s using the longitudinal approach (p = 0.43). The mean difficulty score out of 10 was 3.97 for the cross-sectional approach and 3.93 for the longitudinal approach (p = 0.95). We found no significant difference in effectiveness between the cross-sectional and longitudinal approaches to ultrasound-guided venepuncture when performed on a model. We believe that both approaches should be included when teaching ultrasound-guided peripheral vascular access. To confirm which approach would be best in clinical practice, we advocate future testing of both approaches on patients.

Memory-Guided Attention: Independent Contributions of the Hippocampus and Striatum.

PubMed

Goldfarb, Elizabeth V; Chun, Marvin M; Phelps, Elizabeth A

2016-01-20

Memory can strongly influence how attention is deployed in future encounters. Though memory dependent on the medial temporal lobes has been shown to drive attention, how other memory systems could concurrently and comparably enhance attention is less clear. Here, we demonstrate that both reinforcement learning and context memory facilitate attention in a visual search task. Using functional magnetic resonance imaging, we dissociate the mechanisms by which these memories guide attention: trial by trial, the hippocampus (not the striatum) predicted attention benefits from context memory, while the striatum (not the hippocampus) predicted facilitation from rewarded stimulus-response associations. Responses in these regions were also distinctly correlated with individual differences in each type of memory-guided attention. This study provides novel evidence for the role of the striatum in guiding attention, dissociable from hippocampus-dependent context memory.

Memory-Guided Attention: Independent Contributions of the Hippocampus and Striatum

PubMed Central

Goldfarb, Elizabeth V.; Chun, Marvin M.; Phelps, Elizabeth A.

2015-01-01

SUMMARY Memory can strongly influence how attention is deployed in future encounters. Though memory dependent on the medial temporal lobes has been shown to drive attention, how other memory systems could concurrently and comparably enhance attention is less clear. Here, we demonstrate that both reinforcement learning and context memory facilitate attention in a visual search task. Using functional magnetic resonance imaging, we dissociate the mechanisms by which these memories guide attention: trial by trial, the hippocampus (not the striatum) predicted attention benefits from context memory, while the striatum (not the hippocampus) predicted facilitation from rewarded stimulus-response associations. Responses in these regions were also distinctly correlated with individual differences in each type of memory-guided attention. This study provides novel evidence for the role of the striatum in guiding attention, dissociable from hippocampus-dependent context memory. PMID:26777274

Review of in situ derivatization techniques for enhanced bioanalysis using liquid chromatography with mass spectrometry.

PubMed

Baghdady, Yehia Z; Schug, Kevin A

2016-01-01

Accurate and specific analysis of target molecules in complex biological matrices remains a significant challenge, especially when ultra-trace detection limits are required. Liquid chromatography with mass spectrometry is often the method of choice for bioanalysis. Conventional sample preparation and clean-up methods prior to the analysis of biological fluids such as liquid-liquid extraction, solid-phase extraction, or protein precipitation are time-consuming, tedious, and can negatively affect target recovery and detection sensitivity. An alternative or complementary strategy is the use of an off-line or on-line in situ derivatization technique. In situ derivatization can be incorporated to directly derivatize target analytes in their native biological matrices, without any prior sample clean-up methods, to substitute or even enhance the extraction and preconcentration efficiency of these traditional sample preparation methods. Designed appropriately, it can reduce the number of sample preparation steps necessary prior to analysis. Moreover, in situ derivatization can be used to enhance the performance of the developed liquid chromatography with mass spectrometry-based bioanalysis methods regarding stability, chromatographic separation, selectivity, and ionization efficiency. This review presents an overview of the commonly used in situ derivatization techniques coupled to liquid chromatography with mass spectrometry-based bioanalysis to guide and to stimulate future research. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Implementation of a Multiplex and Quantitative Proteomics Platform for Assessing Protein Lysates Using DNA-Barcoded Antibodies.

PubMed

Lee, Jinho; Geiss, Gary K; Demirkan, Gokhan; Vellano, Christopher P; Filanoski, Brian; Lu, Yiling; Ju, Zhenlin; Yu, Shuangxing; Guo, Huifang; Bogatzki, Lisa Y; Carter, Warren; Meredith, Rhonda K; Krishnamurthy, Savitri; Ding, Zhiyong; Beechem, Joseph M; Mills, Gordon B

2018-06-01

Molecular analysis of tumors forms the basis for personalized cancer medicine and increasingly guides patient selection for targeted therapy. Future opportunities for personalized medicine are highlighted by the measurement of protein expression levels via immunohistochemistry, protein arrays, and other approaches; however, sample type, sample quantity, batch effects, and "time to result" are limiting factors for clinical application. Here, we present a development pipeline for a novel multiplexed DNA-labeled antibody platform which digitally quantifies protein expression from lysate samples. We implemented a rigorous validation process for each antibody and show that the platform is amenable to multiple protocols covering nitrocellulose and plate-based methods. Results are highly reproducible across technical and biological replicates, and there are no observed "batch effects" which are common for most multiplex molecular assays. Tests from basal and perturbed cancer cell lines indicate that this platform is comparable to orthogonal proteomic assays such as Reverse-Phase Protein Array, and applicable to measuring the pharmacodynamic effects of clinically-relevant cancer therapeutics. Furthermore, we demonstrate the potential clinical utility of the platform with protein profiling from breast cancer patient samples to identify molecular subtypes. Together, these findings highlight the potential of this platform for enhancing our understanding of cancer biology in a clinical translation setting. © 2018 by The American Society for Biochemistry and Molecular Biology, Inc.

Impact Induced Delamination Detection and Quantification With Guided Wavefield Analysis

NASA Technical Reports Server (NTRS)

Tian, Zhenhua; Leckey, Cara A. C.; Yu, Lingyu; Seebo, Jeffrey P.

2015-01-01

This paper studies impact induced delamination detection and quantification by using guided wavefield data and spatial wavenumber imaging. The complex geometry impact-like delamination is created through a quasi-static indentation on a CFRP plate. To detect and quantify the impact delamination in the CFRP plate, PZT-SLDV sensing and spatial wavenumber imaging are performed. In the PZT-SLDV sensing, the guided waves are generated from the PZT, and the high spatial resolution guided wavefields are measured by the SLDV. The guided wavefield data acquired from the PZT-SLDV sensing represent guided wave propagation in the composite laminate and include guided wave interaction with the delamination damage. The measured guided wavefields are analyzed through the spatial wavenumber imaging method, which generates an image containing the dominant local wavenumber at each spatial location. The spatial wavenumber imaging result for the simple single layer Teflon insert delamination provided quantitative information on delamination damage size and location. The location of delamination damage is indicated by the area with larger wavenumbers in the spatial wavenumber image. The impact-like delamination results only partially agreed with the damage size and shape. The results also demonstrated the dependence on excitation frequency. Future work will further investigate the accuracy of the wavenumber imaging method for real composite damage and the dependence on frequency of excitation.

Change Detection via Selective Guided Contrasting Filters

NASA Astrophysics Data System (ADS)

Vizilter, Y. V.; Rubis, A. Y.; Zheltov, S. Y.

2017-05-01

Change detection scheme based on guided contrasting was previously proposed. Guided contrasting filter takes two images (test and sample) as input and forms the output as filtered version of test image. Such filter preserves the similar details and smooths the non-similar details of test image with respect to sample image. Due to this the difference between test image and its filtered version (difference map) could be a basis for robust change detection. Guided contrasting is performed in two steps: at the first step some smoothing operator (SO) is applied for elimination of test image details; at the second step all matched details are restored with local contrast proportional to the value of some local similarity coefficient (LSC). The guided contrasting filter was proposed based on local average smoothing as SO and local linear correlation as LSC. In this paper we propose and implement new set of selective guided contrasting filters based on different combinations of various SO and thresholded LSC. Linear average and Gaussian smoothing, nonlinear median filtering, morphological opening and closing are considered as SO. Local linear correlation coefficient, morphological correlation coefficient (MCC), mutual information, mean square MCC and geometrical correlation coefficients are applied as LSC. Thresholding of LSC allows operating with non-normalized LSC and enhancing the selective properties of guided contrasting filters: details are either totally recovered or not recovered at all after the smoothing. These different guided contrasting filters are tested as a part of previously proposed change detection pipeline, which contains following stages: guided contrasting filtering on image pyramid, calculation of difference map, binarization, extraction of change proposals and testing change proposals using local MCC. Experiments on real and simulated image bases demonstrate the applicability of all proposed selective guided contrasting filters. All implemented filters provide the robustness relative to weak geometrical discrepancy of compared images. Selective guided contrasting based on morphological opening/closing and thresholded morphological correlation demonstrates the best change detection result.

The National Problem of Untested Sexual Assault Kits (SAKs): Scope, Causes, and Future Directions for Research, Policy, and Practice.

PubMed

Campbell, Rebecca; Feeney, Hannah; Fehler-Cabral, Giannina; Shaw, Jessica; Horsford, Sheena

2015-12-23

Victims of sexual assault are often advised to have a medical forensic exam and sexual assault kit (SAK; also termed a "rape kit") to preserve physical evidence (e.g., semen, blood, and/or saliva samples) to aid in the investigation and prosecution of the crime. Law enforcement are tasked with submitting the rape kit to a forensic laboratory for DNA (deoxyribonucleic acid) analysis, which can be instrumental in identifying offenders in previously unsolved crimes, confirming identify in known-offender assaults, discovering serial rapists, and exonerating individuals wrongly accused. However, a growing number of media stories, investigative advocacy projects, and social science studies indicate that police are not routinely submitting SAKs for forensic testing, and instead rape kits are placed in evidence storage, sometimes for decades. This review article examines the growing national problem of untested rape kits by summarizing current research on the number of untested SAKs in the United States and exploring the underlying reasons why police do not submit this evidence for DNA testing. Recommendations for future research that can guide policy and practice are discussed. © The Author(s) 2015.

2017 Brownfields Federal Programs Guide

EPA Pesticide Factsheets

This document illustrates how the Brownfields Program does more than address environmental contamination—it recognizes a community’s quality of life aligning with economic development and sustainability, and looks to the future for revitalization.

Design guide for low cost standardized payloads, volume 1

NASA Technical Reports Server (NTRS)

1972-01-01

Concept point designs of low cost and refurbishable spacecraft, subsystems, and modules revealed payload program savings up to 50 percent. The general relationship of payload approaches to program costs; cost reductions from low cost standardized payloads; cost effective application of payload reliability, MMD, repair, and refurbishment; and implementation of standardization for future spacecraft are discussed. Shuttle interfaces and support equipment for future payloads are also considered

Critical Trends and Events Affecting the Future of Community Colleges: Proceedings of a Beyond 2000 Preconference Workshop (Orlando, Florida, February 26-28, 1995).

ERIC Educational Resources Information Center

Morrison, James L.

The Beyond 2000 workshop held in February 1995 was designed to give participants experience in using strategic management techniques, such as critical trend and potential event identification, to examine the future of community colleges. This paper is intended as a guide for implementing similar workshops and summarizes the outcomes of workshop…

Full-Time Non-Tenure-Track Faculty: Current Status, Future Prospects, Remaining Research Questions. ASHE Annual Meeting Paper.

ERIC Educational Resources Information Center

Chronister, Jay L.; And Others

This study used available data to develop an initial profile of non-tenure-track (NTT) faculty in comparison to their non-tenured but tenure track (TT) counterparts and to develop questions to guide future study of this group. Using data from a 1989 survey of the professorate conducted by the Carnegie Foundation for the Advancement of Teaching,…

The architecture challenge: Future artificial-intelligence systems will require sophisticated architectures, and knowledge of the brain might guide their construction.

PubMed

Baldassarre, Gianluca; Santucci, Vieri Giuliano; Cartoni, Emilio; Caligiore, Daniele

2017-01-01

In this commentary, we highlight a crucial challenge posed by the proposal of Lake et al. to introduce key elements of human cognition into deep neural networks and future artificial-intelligence systems: the need to design effective sophisticated architectures. We propose that looking at the brain is an important means of facing this great challenge.

The Transforming Mobility Ecosystem: Enabling in Energy-Efficient Future

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

Over the next decade, the transportation sector is poised for rapid change, propelled toward a new mobility future by strong technology currents and the confluence of prevailing megatrends. These major forces hold the promise of shaping a new mobility future – one that unlocks tremendous economic value, provides unprecedented gains in safety, offers affordable and equal accessibility, and enables the transition to energy-efficient transport of people and goods. They come, however, with cautionary viewpoints on energy consumption of the entire sector, necessitating the need to carefully guide the emergent future. This report examines four possible mobility futures that could existmore » in 2050 and the positive and negative impacts of these futures on energy consumption and the broader economy.« less

The relationship between decorrelation time and sample thickness in acute rat brain tissue slices (Conference Presentation)

NASA Astrophysics Data System (ADS)

Brake, Joshua; Jang, Mooseok; Yang, Changhuei

2016-03-01

The optical opacity of biological tissue has long been a challenge in biomedical optics due to the strong scattering nature of tissue in the optical regime. While most conventional optical techniques attempt to gate out multiply scattered light and use only unscattered light, new approaches in the field of wavefront shaping exploit the time reversible symmetry of optical scattering in order to focus light inside or through scattering media. While these approaches have been demonstrated effectively on static samples, it has proven difficult to apply them to dynamic biological samples since even small changes in the relative positions of the scatterers within will cause the time symmetry that wavefront shaping relies upon to decorrelate. In this paper we investigate the decorrelation curves of acute rat brain slices for thicknesses in the range 1-3 mm (1/e decorrelation time on the order of seconds) using multi-speckle diffusing wave spectroscopy (MSDWS) and compare the results with theoretical predictions. The results of this study demonstrate that the 1/L^2 relationship between decorrelation time and thickness predicted by diffusing wave spectroscopy provides a good rule of thumb for estimating how the decorrelation of a sample will change with increasing thickness. Understanding this relationship will provide insight to guide the future development of biophotonic wavefront shaping tools by giving an estimate of how fast wavefront shaping systems need to operate to overcome the dynamic nature of biological samples.

Sampling for pharmaceuticals and personal care products (PPCPs) and illicit drugs in wastewater systems: are your conclusions valid? A critical review.

PubMed

Ort, Christoph; Lawrence, Michael G; Rieckermann, Jörg; Joss, Adriano

2010-08-15

The analysis of 87 peer-reviewed journal articles reveals that sampling for pharmaceuticals and personal care products (PPCPs) and illicit drugs in sewers and sewage treatment plant influents is mostly carried out according to existing tradition or standard laboratory protocols. Less than 5% of all studies explicitly consider internationally acknowledged guidelines or methods for the experimental design of monitoring campaigns. In the absence of a proper analysis of the system under investigation, the importance of short-term pollutant variations was typically not addressed. Therefore, due to relatively long sampling intervals, potentially inadequate sampling modes, or insufficient documentation, it remains unclear for the majority of reviewed studies whether observed variations can be attributed to "real" variations or if they simply reflect sampling artifacts. Based on results from previous and current work, the present paper demonstrates that sampling errors can lead to overinterpretation of measured data and ultimately, wrong conclusions. Depending on catchment size, sewer type, sampling setup, substance of interest, and accuracy of analytical method, avoidable sampling artifacts can range from "not significant" to "100% or more" for different compounds even within the same study. However, in most situations sampling errors can be reduced greatly, and sampling biases can be eliminated completely, by choosing an appropriate sampling mode and frequency. This is crucial, because proper sampling will help to maximize the value of measured data for the experimental assessment of the fate of PPCPs as well as for the formulation and validation of mathematical models. The trend from reporting presence or absence of a compound in "clean" water samples toward the quantification of PPCPs in raw wastewater requires not only sophisticated analytical methods but also adapted sampling methods. With increasing accuracy of chemical analyses, inappropriate sampling increasingly represents the major source of inaccuracy. A condensed step-by-step Sampling Guide is proposed as a starting point for future studies.

Characterization of the decision-making deficit of patients with ventromedial prefrontal cortex lesions.

PubMed

Bechara, A; Tranel, D; Damasio, H

2000-11-01

On a gambling task that models real-life decisions, patients with bilateral lesions of the ventromedial prefrontal cortex (VM) opt for choices that yield high immediate gains in spite of higher future losses. In this study, we addressed three possibilities that may account for this behaviour: (i) hypersensitivity to reward; (ii) insensitivity to punishment; and (iii) insensitivity to future consequences, such that behaviour is always guided by immediate prospects. For this purpose, we designed a variant of the original gambling task in which the advantageous decks yielded high immediate punishment but even higher future reward. The disadvantageous decks yielded low immediate punishment but even lower future reward. We measured the skin conductance responses (SCRs) of subjects after they had received a reward or punishment. Patients with VM lesions opted for the disadvantageous decks in both the original and variant versions of the gambling task. The SCRs of VM lesion patients after they had received a reward or punishment were not significantly different from those of controls. In a second experiment, we investigated whether increasing the delayed punishment in the disadvantageous decks of the original task or decreasing the delayed reward in the disadvantageous decks of the variant task would shift the behaviour of VM lesion patients towards an advantageous strategy. Both manipulations failed to shift the behaviour of VM lesion patients away from the disadvantageous decks. These results suggest that patients with VM lesions are insensitive to future consequences, positive or negative, and are primarily guided by immediate prospects. This 'myopia for the future' in VM lesion patients persists in the face of severe adverse consequences, i.e. rising future punishment or declining future reward.

Diet self-management and readiness to change in underserved adults with type 2 diabetes.

PubMed

Knight, Holly; Stetson, Barbara; Krishnasamy, Sathya; Mokshagundam, Sri Prakash

2015-06-01

Dietary assessment in diabetes may be enhanced by considering patient-centered perspectives and barriers to change within IDF guidelines. Consideration of readiness to change (RTC) diet in underserved samples may guide future interventions in high risk populations. This study assesses the utility of a rapid assessment of RTC diet in a medically underserved sample. Participants were 253 Black (43.7%) and White (55.1%) American adults with type 2 diabetes [M age=57.93 (11.52); 60.5% female; 19% below the US poverty threshold]. Participants were recruited at medical clinics and completed validated self-report measures assessing diabetes knowledge, self-efficacy and dietary behaviors and barriers by RTC. Stage-based comparisons identified significant differences in diabetes and dietary domains: participants in the Action stage endorsed fewer behavioral dietary barriers (p<.001), more frequent dietary problem-solving (p<.001), and greater diabetes self-efficacy (p<.001) than participants in the Contemplation and Preparation stages. Women were more likely to be in the Preparation stage and beyond (p<.05). Findings highlight the clinical utility of a brief measure of RTC in understanding patient perspectives toward dietary behaviors in a medically underserved sample. The impact of gender on RTC diet warrants further exploration. Copyright © 2014 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.

"It's for a good cause, isn't it?" - Exploring views of South African TB research participants on sample storage and re-use

PubMed Central

2012-01-01

Background The banking of biological samples raises a number of ethical issues in relation to the storage, export and re-use of samples. Whilst there is a growing body of literature exploring participant perspectives in North America and Europe, hardly any studies have been reported in Africa. This is problematic in particular in light of the growing amount of research taking place in Africa, and with the rise of biobanking practices also on the African continent. In order to investigate the perspectives of African research participants, we conducted a study with research participants in a TB study in the Western Cape, South Africa. Methods Semi-structured interviews were conducted using an interview guide which drew on the most prominent themes expressed in current literature on sample storage, re-use and exportation. Interviews were conducted in Afrikaans and subsequently translated into English by the same interviewer. Interviews were transcribed verbatim and analysed qualitatively. Results The results of our study indicate that the majority of participants were supportive of giving one-time consent to the storage and re-use of their samples. The concept of research being for a “good cause” was a central prerequisite. Additionally, a significant minority requested that they be re-contacted if a future use was not stipulated on the original consent. There was also considerable variation in how participants understood the concept of a ‘good cause’, with participants describing three distinct categories of research, of which two were generally thought to constitute ‘good cause’ research. Research that was for-profit was considered to fall outside the spectrum of ‘good cause’ research. Participants displayed confidence in the abilities of the researchers to make future decisions regarding sample use, but seemed unaware of the role of ethics committees in either this process or more generally. Conclusions Participants expressed a wide and complex range of views about issues of sample storage and re-use, and they showed a great deal of trust in researchers. Participants’ willingness to have their samples stored and re-used is consistent with findings from existing studies. However, in contrast to existing literature, participants were generally not in favour of for-profit research. Further research needs to be done to explore these ideas in other communities, both in South Africa and other countries. PMID:22831568

"It's for a good cause, isn't it?" - Exploring views of South African TB research participants on sample storage and re-use.

PubMed

van Schalkwyk, Gerrit; de Vries, Jantina; Moodley, Keymanthri

2012-07-25

The banking of biological samples raises a number of ethical issues in relation to the storage, export and re-use of samples. Whilst there is a growing body of literature exploring participant perspectives in North America and Europe, hardly any studies have been reported in Africa. This is problematic in particular in light of the growing amount of research taking place in Africa, and with the rise of biobanking practices also on the African continent. In order to investigate the perspectives of African research participants, we conducted a study with research participants in a TB study in the Western Cape, South Africa. Semi-structured interviews were conducted using an interview guide which drew on the most prominent themes expressed in current literature on sample storage, re-use and exportation. Interviews were conducted in Afrikaans and subsequently translated into English by the same interviewer. Interviews were transcribed verbatim and analysed qualitatively. The results of our study indicate that the majority of participants were supportive of giving one-time consent to the storage and re-use of their samples. The concept of research being for a "good cause" was a central prerequisite. Additionally, a significant minority requested that they be re-contacted if a future use was not stipulated on the original consent. There was also considerable variation in how participants understood the concept of a 'good cause', with participants describing three distinct categories of research, of which two were generally thought to constitute 'good cause' research. Research that was for-profit was considered to fall outside the spectrum of 'good cause' research. Participants displayed confidence in the abilities of the researchers to make future decisions regarding sample use, but seemed unaware of the role of ethics committees in either this process or more generally. Participants expressed a wide and complex range of views about issues of sample storage and re-use, and they showed a great deal of trust in researchers. Participants' willingness to have their samples stored and re-used is consistent with findings from existing studies. However, in contrast to existing literature, participants were generally not in favour of for-profit research. Further research needs to be done to explore these ideas in other communities, both in South Africa and other countries.

Teaching the Interior Composition and Rheology of the Earth to Undergraduate Students Using an Inquiry Based Approach

NASA Astrophysics Data System (ADS)

Hayden, T. G.; Callahan, C. N.; Sibert, R. J.; Ewald, S. K.

2011-12-01

Most introductory geology courses include a lesson on the internal layered structure of the Earth. Due to the abstract nature of the content, this topic is difficult to teach using an inquiry-based approach. The challenge is two-fold: first, students cannot directly see the layers from their perspective on the earth's surface, and second, students have trouble grasping the vast scale of the earth, which far exceeds their everyday experiences. In addition, the two separate classification systems for dividing the internal structure of the Earth are often a point of confusion and source of misconceptions. In response to this challenge, we developed an inquiry lesson that scaffolds students' understanding of the compositional and rheological properties of the Earth's interior. The intent is to build students' understanding of the Earth's layers by guiding their attention to the reasons for the separate classification systems and the individual layers. The investigation includes teacher- or material-driven components such as guiding questions and specific hand-samples for analogues as well as student-driven components like collecting data and constructing explanations. The lesson opens with a series of questions designed to elicit students' existing ideas about the Earth's interior. The students are then guided to make observations of hand samples meant to represent examples of the crust and mantle as well as physical materials meant to serve as analogues for the lithosphere and asthenosphere. The lesson concludes with students integrating their observations into a model of the Earth's internal structure that accounts for both the compositional and rheological properties. Although this lesson was originally developed as a roughly 60 minute lesson for a class of 24 students, we also note ways this lesson can be modified for use at a variety of course levels. The lesson was pilot-tested in an introductory Earth Science course for future elementary (K-8) teachers. Data collected includes both pre- and post-instruction drawings as well as responses to multiple-choice test items derived from the Geoscience Content Inventory (GCI).

Food Production, Management, and Services: Curriculum Guide.

ERIC Educational Resources Information Center

Mumme, Debbie; Koukel, Sonja

This curriculum guide provides occupationally specific training designed to develop knowledge and skills for employment in the area of food production, management, and services. Contents include the Texas Essential Knowledge and Skills (TEAKS); sample course outlines; instructional strategies organized topically by chapters, each containing a…

Textile & Apparel Production, Management, and Services: Curriculum Guide.

ERIC Educational Resources Information Center

Killman, Letitia

This curriculum guide contains materials for a course that provides occupationally specific training designed to develop knowledge and skills for employment in the textile and apparel industries. Contents include an introduction; the Texas Essential Knowledge and Skills (TEKS) covered; sample course outlines; instructional strategies organized…

Services for Older Adults: Curriculum Guide.

ERIC Educational Resources Information Center

Mumme, Debbie

This curriculum guide contains materials for a course that provides occupationally specific training designed to develop knowledge and skills for employment in the area of services for older adults. Contents include an introduction, the Texas Essential Knowledge and Skills (TEKS) covered; sample course outlines; instructional strategies organized…

Creation of the selection list for the Experiment Scheduling Program (ESP)

NASA Technical Reports Server (NTRS)

Deuermeyer, B. L.; Shannon, R. E.; Underbrink, A. J., Jr.

1986-01-01

The efforts to develop a procedure to construct selection groups to augment the Experiment Scheduling Program (ESP) are summarized. Included is a User's Guide and a sample scenario to guide in the use of the software system that implements the developed procedures.

Elementary Science Resource Guide.

ERIC Educational Resources Information Center

Texas Education Agency, Austin. Div. of Curriculum Development.

This guide for elementary teachers provides information on getting ideas into action, designing and implementing the right situation, ways in which to evaluate science process activities with students, and seven sample units. The units cover using the senses, magnets, forces, weather forecasting, classification of living things, and the physical…

Planning Resource Guide.

ERIC Educational Resources Information Center

RP Group of California Community Colleges, Santa Ana.

The Planning Resource Guide by the RP Group of California Community Colleges was created to provide practical planning assistance. It contains four sections, including: (1) a basic conceptual framework for planning; (2) common planning definitions for colleges; (3) planning steps and samples of planning structures; and (4) suggestions for linking…

Everett Transit 1994,Comprehensive Plan

DOT National Transportation Integrated Search

1994-09-07

Everett Transit's Comprehensive Plann provides the long-term framework to guide : the development of public transportation services in Everett over the next : twenty years. In this plan, Everett Transit clearly defines its mission, future : direction...

Modeling of the focusing device and the elliptical neutron guide for the DN-6 diffractometer at IBR-2 reactor

NASA Astrophysics Data System (ADS)

Belushkin, A. V.; Manoshin, S. A.; Kozlenko, D. P.; Kichanov, S. E.

2018-06-01

Possible options for modernization of the neutron beam forming system of the DN-6 diffractometer for the study of crystal and magnetic structures of microsamples at high pressures are being considered. It was demonstrated that for samples with the cross-section not exceeding 5 × 5 mm2 the most efficient option would be the use of an elliptical neutron guide. It allows to deliver neutrons for large distances from the source to samples with minimal losses using, as a rule, just one neutron reflection per dimension i.e. one at a side and one at top or bottom. For the present moment due to technical difficulties of such option realization, the simplified solution was proposed. At the end of the curved neutron guide it is planned to install a vertical plane focusing 7-meter-long parabolic section. Such a modernization will increase the neutron flux at the sample by a factor 1.5-3.5 and reduce respectively the typical measurement times.

Visual short-term memory guides infants' visual attention.

PubMed

Mitsven, Samantha G; Cantrell, Lisa M; Luck, Steven J; Oakes, Lisa M

2018-08-01

Adults' visual attention is guided by the contents of visual short-term memory (VSTM). Here we asked whether 10-month-old infants' (N = 41) visual attention is also guided by the information stored in VSTM. In two experiments, we modified the one-shot change detection task (Oakes, Baumgartner, Barrett, Messenger, & Luck, 2013) to create a simplified cued visual search task to ask how information stored in VSTM influences where infants look. A single sample item (e.g., a colored circle) was presented at fixation for 500 ms, followed by a brief (300 ms) retention interval and then a test array consisting of two items, one on each side of fixation. One item in the test array matched the sample stimulus and the other did not. Infants were more likely to look at the non-matching item than at the matching item, demonstrating that the information stored rapidly in VSTM guided subsequent looking behavior. Copyright © 2018 Elsevier B.V. All rights reserved.

The Solar Dynamics Observatory Education and Public Outreach Program: The First Years

NASA Astrophysics Data System (ADS)

Wawro, M.; Drobnes, E.; van Doren, A.; Scherrer, D. K.

2010-12-01

The Solar Dynamics Observatory (SDO) Education and Public Outreach (E/PO) program began as a series of discrete programs implemented by each of the instrument teams and has evolved into a well-rounded program with a full suite of national and international programs: student, teacher, and journalist workshops, international research programs, family programs, etc. In this presentation, we provide an overview of our philosophy and approach and of some of the programs developed and implemented prior to launch. In conclusion we will summarize our successes, our failures, our lessons learned, and present guiding principles in the hope that future missions will use our platform as a guide to build upon for future programs, incorporating their own content to enhance the public's appreciation of the science that NASA does and its benefit to society.

Permanent change of station: The NASA employee's guide to an easier move

NASA Technical Reports Server (NTRS)

1993-01-01

This guide is for the NASA employee preparing to make a permanent change of station. Whether a transferee or a new appointee, this guide contains information that will help a Government-authorized move go more smoothly from start to finish. The guide outlines the allowances and expense reimbursements one is entitled to under Federal Travel Regulations (FTR). It provides samples of forms one may need to fill out to start the transfer rolling and to claim reimbursements. However, it is important to note that this guide is not a copy of the FTR. Information in the FTR and the NASA Travel Regulations, FMM 9760, is far more detailed and is always updated and correct.

Hypnotherapy for insomnia: a systematic review and meta-analysis of randomized controlled trials.

PubMed

Lam, Tak-Ho; Chung, Ka-Fai; Yeung, Wing-Fai; Yu, Branda Yee-Man; Yung, Kam-Ping; Ng, Tommy Ho-Yee

2015-10-01

To examine the efficacy and safety of hypnotherapy for insomnia as compared to placebo, pharmacological or non-pharmacological intervention, or no treatment. A systematic search on major electronic databases was conducted up until March 2014. Inclusion criteria are: (1) randomized controlled trials (RCTs) or quasi-RCTs; (2) intervention targeted at improving sleep; (3) hypnosis as an intervention; and (4) English language articles. Sleep diary variable is the primary outcome measure. Six RCTs of hypnotherapy and seven on autogenic training or guided imagery, comprising 502 subjects, were included. Eleven of the 13 studies had low methodological quality, as indicated by a modified Jadad score below 3, and high risks of bias in blinding and design of the control interventions. No adverse events related to hypnosis were reported, though seldom investigated. Meta-analyses found hypnotherapy significantly shortened sleep latency compared to waitlist (standardized mean difference, SMD=-0.88, 95% confidence interval (CI): -1.56, -0.19, P=0.01, I(2)=15%), but no difference compared to sham intervention (SMD: -1.08, 95% CI: -3.15, 0.09, P=0.31, I(2)=90%). Similar results were found for autogenic training or guided imagery (SMD with waitlist=-1.16, 95% CI: -1.92, -0.40, P=0.003, I(2)=0%; SMD with sham intervention=-0.50, 95% CI: -1.19, 0.19, P=0.15, I(2)=0%). Generalizability of the positive results is doubtful due to the relatively small sample size and methodological limitations. Future studies with larger sample size and better study design and methodology are called for. Copyright © 2015 Elsevier Ltd. All rights reserved.

Saliency-Guided Change Detection of Remotely Sensed Images Using Random Forest

NASA Astrophysics Data System (ADS)

Feng, W.; Sui, H.; Chen, X.

2018-04-01

Studies based on object-based image analysis (OBIA) representing the paradigm shift in change detection (CD) have achieved remarkable progress in the last decade. Their aim has been developing more intelligent interpretation analysis methods in the future. The prediction effect and performance stability of random forest (RF), as a new kind of machine learning algorithm, are better than many single predictors and integrated forecasting method. In this paper, we present a novel CD approach for high-resolution remote sensing images, which incorporates visual saliency and RF. First, highly homogeneous and compact image super-pixels are generated using super-pixel segmentation, and the optimal segmentation result is obtained through image superimposition and principal component analysis (PCA). Second, saliency detection is used to guide the search of interest regions in the initial difference image obtained via the improved robust change vector analysis (RCVA) algorithm. The salient regions within the difference image that correspond to the binarized saliency map are extracted, and the regions are subject to the fuzzy c-means (FCM) clustering to obtain the pixel-level pre-classification result, which can be used as a prerequisite for superpixel-based analysis. Third, on the basis of the optimal segmentation and pixel-level pre-classification results, different super-pixel change possibilities are calculated. Furthermore, the changed and unchanged super-pixels that serve as the training samples are automatically selected. The spectral features and Gabor features of each super-pixel are extracted. Finally, superpixel-based CD is implemented by applying RF based on these samples. Experimental results on Ziyuan 3 (ZY3) multi-spectral images show that the proposed method outperforms the compared methods in the accuracy of CD, and also confirm the feasibility and effectiveness of the proposed approach.

Understanding London's Water Supply Tradeoffs When Scheduling Interventions Under Deep Uncertainty

NASA Astrophysics Data System (ADS)

Huskova, I.; Matrosov, E. S.; Harou, J. J.; Kasprzyk, J. R.; Reed, P. M.

2015-12-01

Water supply planning in many major world cities faces several challenges associated with but not limited to climate change, population growth and insufficient land availability for infrastructure development. Long-term plans to maintain supply-demand balance and ecosystem services require careful consideration of uncertainties associated with future conditions. The current approach for London's water supply planning utilizes least cost optimization of future intervention schedules with limited uncertainty consideration. Recently, the focus of the long-term plans has shifted from solely least cost performance to robustness and resilience of the system. Identifying robust scheduling of interventions requires optimizing over a statistically representative sample of stochastic inputs which may be computationally difficult to achieve. In this study we optimize schedules using an ensemble of plausible scenarios and assess how manipulating that ensemble influences the different Pareto-approximate intervention schedules. We investigate how a major stress event's location in time as well as the optimization problem formulation influence the Pareto-approximate schedules. A bootstrapping method that respects the non-stationary trend of climate change scenarios and ensures the even distribution of the major stress event in the scenario ensemble is proposed. Different bootstrapped hydrological scenario ensembles are assessed using many-objective scenario optimization of London's future water supply and demand intervention scheduling. However, such a "fixed" scheduling of interventions approach does not aim to embed flexibility or adapt effectively as the future unfolds. Alternatively, making decisions based on the observations of occurred conditions could help planners who prefer adaptive planning. We will show how rules to guide the implementation of interventions based on observations may result in more flexible strategies.

The Deployment Life Study: Longitudinal Analysis of Military Families Across the Deployment Cycle

DTIC Science & Technology

2016-01-01

psychological and physical aggression than they reported prior to the deployment. 1 H. Fischer, A Guide to U.S. Military Casualty Statistics ...analyses include a large number of statistical tests and thus the results pre- sented in this report should be viewed in terms of patterns, rather...Military Children and Families,” The Future of Children, Vol. 23, No. 2, 2013, pp. 13–39. Fischer, H., A Guide to U.S. Military Casualty Statistics

Total Quality Management Guide. A Two Volume Guide for Defense Organizations. Volume 1. Key Features of the DoD Implementation

DTIC Science & Technology

1990-02-15

XIALTM DoD 5000.51-G A * FINAL DRAFT 2/15/90 si- N ~LUM I -KY FEATRES OFTHE Do IMLEENAON TOTAL L/ De~rrn QUADefens FOREWORD Government and industry...away with all government inspectors. Rather. government oversight will change from te large scale product inspection and specifying the -how to...in class" - Set the course for the future, and - Provide a baseline for measuring progress. Benchmarking is a continuous process of comparing an

Construction of a high-tech operating room for image-guided surgery using VR.

PubMed

Suzuki, Naoki; Hattori, Asaki; Suzuki, Shigeyuki; Otake, Yoshito; Hayashibe, Mitsuhiro; Kobayashi, Susumu; Nezu, Takehiko; Sakai, Haruo; Umezawa, Yuji

2005-01-01

This project aimed to construct an operating room to implement high dimensional (3D, 4D) medical imaging and medical virtual reality techniques that would enable clinical tests for new surgical procedures. We designed and constructed such an operating room at Dai-san Hospital, the Jikei Univ. School of Medicine, Tokyo, Japan. The room was equipped with various facilities for image-guided, robot and tele- surgery. In this report, we describe an outline of our "high-tech operating room" and future plans.

Planning, Development, and Change in Bristol Bay: A High School Curriculum. Teacher Guide and Student Text. Unit V: Oil and Gas Development. Unit VI: Minerals and Mining. Unit VII: State Land Disposal. Revised

ERIC Educational Resources Information Center

Lipka, Jerry; Willer, Cristy

Written with the broad goal of involving high school students in Bristol Bay, Alaska, in the planning and design of their region's future, this combined teacher guide and student text contains the final three units of a seven-unit curriculum. Unit V looks at oil development in the Bering Sea, covering topics such as Alaska's dependence on oil,…

Customized sampling plans : a guide to alternative sampling techniques for National Transit Database reporting

DOT National Transportation Integrated Search

2004-05-01

For estimating the system total unlinked passenger trips and passenger miles of a fixed-route bus system for the National Transit Database (NTD), the FTA approved sampling plans may either over-sample or do not yield FTAs required confidence and p...

An Organic Decontamination Method for Sampling Devices used in Life-detection Studies

NASA Technical Reports Server (NTRS)

Eigenbrode, Jennifer; Maule, Jake; Wainwright, Norm; Steele, Andrew; Amundsen, Hans E.F.

2008-01-01

Organic decontamination of sampling and storage devices are crucial steps for life-detection, habitability, and ecological investigations of extremophiles living in the most inhospitable niches of Earth, Mars and elsewhere. However, one of the main stumbling blocks for Mars-analogue life-detection studies in terrestrial remote field-sites is the capability to clean instruments and sampling devices to organic levels consistent with null values. Here we present a new seven-step, multi-reagent cleaning and decontamination protocol that was adapted and tested on a glacial ice-coring device and on a rover-guided scoop used for sediment sampling both deployed multiple times during two field seasons of the Arctic Mars Analog Svalbard Expedition AMASE). The effectiveness of the protocols for both devices was tested by (1)in situ metabolic measurements via APT, (2)in situ lipopolysacchride (LPS) quantifications via low-level endotoxin assays, and(3) laboratory-based molecular detection via gas chromatography-mass spectrometry. Our results show that the combination and step-wise application of disinfectants with oxidative and solvation properties for sterilization are effective at removing cellular remnants and other organic traces to levels necessary for molecular organic- and life-detection studies. The validation of this seven-step protocol - specifically for ice sampling - allows us to proceed with confidence in kmskia4 analogue investigations of icy environments. However, results from a rover scoop test showed that this protocol is also suitable for null-level decontamination of sample acquisition devices. Thus, this protocol may be applicable to a variety of sampling devices and analytical instrumentation used for future astrobiology missions to Enceladus, and Europa, as well as for sample-return missions.

Breast cancer: determining the genetic profile from ultrasound-guided percutaneous biopsy specimens obtained during the diagnostic workups.

PubMed

López Ruiz, J A; Zabalza Estévez, I; Mieza Arana, J A

2016-01-01

To evaluate the possibility of determining the genetic profile of primary malignant tumors of the breast from specimens obtained by ultrasound-guided percutaneous biopsies during the diagnostic imaging workup. This is a retrospective study in 13 consecutive patients diagnosed with invasive breast cancer by B-mode ultrasound-guided 12 G core needle biopsy. After clinical indication, the pathologist decided whether the paraffin block specimens seemed suitable (on the basis of tumor size, validity of the sample, and percentage of tumor cells) before sending them for genetic analysis with the MammaPrint® platform. The size of the tumors on ultrasound ranged from 0.6cm to 5cm. In 11 patients the preserved specimen was considered valid and suitable for use in determining the genetic profile. In 1 patient (with a 1cm tumor) the pathologist decided that it was necessary to repeat the core biopsy to obtain additional samples. In 1 patient (with a 5cm tumor) the specimen was not considered valid by the genetic laboratory. The percentage of tumor cells in the samples ranged from 60% to 70%. In 11/13 cases (84.62%) it was possible to do the genetic analysis on the previously diagnosed samples. In most cases, regardless of tumor size, it is possible to obtain the genetic profile from tissue specimens obtained with ultrasound-guided 12 G core biopsy preserved in paraffin blocks. Copyright © 2015 SERAM. Published by Elsevier España, S.L.U. All rights reserved.

Review of implementation strategies to change healthcare provider behaviour in the emergency department.

PubMed

de Wit, Kerstin; Curran, Janet; Thoma, Brent; Dowling, Shawn; Lang, Eddy; Kuljic, Nebojsa; Perry, Jeffrey J; Morrison, Laurie

2018-05-01

Advances in emergency medicine research can be slow to make their way into clinical care, and implementing a new evidence-based intervention can be challenging in the emergency department. The Canadian Association of Emergency Physicians (CAEP) Knowledge Translation Symposium working group set out to produce recommendations for best practice in the implementation of a new science in Canadian emergency departments. A systematic review of implementation strategies to change health care provider behaviour in the emergency department was conducted simultaneously with a national survey of emergency physician experience. We summarized our findings into a list of draft recommendations that were presented at the national CAEP Conference 2017 and further refined based on feedback through social media strategies. We produced 10 recommendations for implementing new evidence-based interventions in the emergency department, which cover identifying a practice gap, evaluating the evidence, planning the intervention strategy, monitoring, providing feedback during implementation, and desired qualities of future implementation research. We present recommendations to guide future emergency department implementation initiatives. There is a need for robust and well-designed implementation research to guide future emergency department implementation initiatives.

Fundamental constructs in food parenting practices: a content map to guide future research

PubMed Central

Ward, Dianne S.; Fisher, Jennifer O.; Faith, Myles S.; Hughes, Sheryl O.; Kremers, Stef P.J.; Musher-Eizenman, Dara R.; O’Connor, Teresia M.; Patrick, Heather; Power, Thomas G.

2016-01-01

Although research shows that “food parenting practices” can impact children’s diet and eating habits, current understanding of the impact of specific practices has been limited by inconsistencies in terminology and definitions. This article represents a critical appraisal of food parenting practices, including clear terminology and definitions, by a working group of content experts. The result of this effort was the development of a content map for future research that presents 3 overarching, higher-order food parenting constructs – coercive control, structure, and autonomy support – as well as specific practice subconstructs. Coercive control includes restriction, pressure to eat, threats and bribes, and using food to control negative emotions. Structure includes rules and limits, limited/guided choices, monitoring, meal- and snacktime routines, modeling, food availability and accessibility, food preparation, and unstructured practices. Autonomy support includes nutrition education, child involvement, encouragement, praise, reasoning, and negotiation. Literature on each construct is reviewed, and directions for future research are offered. Clear terminology and definitions should facilitate cross-study comparisons and minimize conflicting findings resulting from previous discrepancies in construct operationalization. PMID:26724487

[The operating room of the future].

PubMed

Broeders, I A; Niessen, W; van der Werken, C; van Vroonhoven, T J

2000-01-29

Advances in computer technology will revolutionize surgical techniques in the next decade. The operating room (OR) of the future will be connected with a laboratory where clinical specialists and researchers prepare image-guided interventions and explore the possibilities of these techniques. The virtual reality is linked to the actual situation in the OR with the aid of navigation instruments. During complicated operations the images prepared preoperatively will be corrected during the operation on the basis of the information obtained peroperatively. MRI currently offers maximal possibilities for image-guided surgery of soft tissues. Simpler techniques such as fluoroscopy and echography will become increasingly integrated in computer-assisted peroperative navigation. The development of medical robot systems will make possible microsurgical procedures by the endoscopic route. Tele-manipulation systems will also play a part in the training of surgeons. Design and construction of the OR will be adapted to the surgical technology, and include an information and control unit where preoperative and peroperative data come together and from where the surgeon operates the instruments. Concepts for the future OR should be regularly adjusted to allow for new surgical technology.

Bioinformatic analyses to select phenotype affecting polymorphisms in HTR2C gene.

PubMed

Piva, Francesco; Giulietti, Matteo; Baldelli, Luisa; Nardi, Bernardo; Bellantuono, Cesario; Armeni, Tatiana; Saccucci, Franca; Principato, Giovanni

2011-08-01

Single nucleotide polymorphisms (SNPs) in serotonin related genes influence mental disorders, responses to pharmacological and psychotherapeutic treatments. In planning association studies, researchers that want to investigate new SNPs have to select some among a large number of candidates. Our aim is to guide researchers in the selection of the most likely phenotype affecting polymorphisms. Here, we studied serotonin receptor 2C (HTR2C) SNPs because, till now, only relatively few of about 2000 are investigated. We used the most updated and assessed bioinformatic tools to predict which variations can give rise to biological effects among 2450 HTR2C SNPs. We suggest 48 SNPs that are worth considering in future association studies in the field of psychiatry, psychology and pharmacogenomics. Moreover, our analyses point out the biological level probably affected, such as transcription, splicing, miRNA regulation and protein structure, thus allowing to suggest future molecular investigations. Although few association studies are available in literature, their results are in agreement with our predictions, showing that our selection methods can help to guide future association studies. Copyright © 2011 John Wiley & Sons, Ltd.

An Analysis of Physician Assistant LibGuides: A Tool for Collection Development.

PubMed

Johnson, Catherine V; Johnson, Scott Y

2017-01-01

The Physician Assistant (PA) specialty encompasses many subject areas and requires many types of library resources. An analysis of PA LibGuides was performed to determine most frequently recommended resources. A sample of LibGuides from U.S. institutions accredited by the Accreditation Review Commission on Education for the Physician Assistant (ARC-PA) was included in this study. Resources presented on guides were tabulated and organized by resource type. Databases and point-of-care tools were the types of resources listed by the most LibGuides. There were over 1,000 books listed on the 45 guides, including over 600 unique books listed. There were fewer journals listed, only 163. Overall, while the 45 LibGuides evaluated list many unique resources in each category, a librarian can create an accepted list of the most frequently listed resources from the data gathered.

University guide to NASA, 1993

NASA Technical Reports Server (NTRS)

1992-01-01

This guide provides brief descriptions of the two NASA Headquarters program offices through which NASA primarily funds universities, the Office of Space Science and Applications and the Office of Aeronautics and Space Technology. It also describes NASA's Office of Commercial Programs, which funds the Centers for the Commercial Development of Space and the Small Business Innovation Research Program. This guide explains the roles played by NASA's eight field centers and the Jet Propulsion Laboratory, and gives a sampling of ongoing NASA-wide educational programs and services. Most importantly, this guide provides practical information in the form of names and telephone numbers of NASA contacts.

Manufacturing Planning Guide

NASA Technical Reports Server (NTRS)

Waid, Michael

2011-01-01

Manufacturing process, milestones and inputs are unknowns to first-time users of the manufacturing facilities. The Manufacturing Planning Guide aids in establishing expectations for both NASA and non-NASA facility customers. The potential audience for this guide includes both internal and commercial spaceflight hardware/software developers. It is intended to assist their project engineering personnel in manufacturing planning and execution. Material covered includes a roadmap of the manufacturing process, roles and responsibilities of facility and user, major milestones, facility capabilities, and inputs required by the facility. Samples of deliverables, products, and inputs necessary to define test scope, cost, and schedule are included as an appendix to the guide.

University guide to NASA, 1993

NASA Astrophysics Data System (ADS)

1992-10-01

This guide provides brief descriptions of the two NASA Headquarters program offices through which NASA primarily funds universities, the Office of Space Science and Applications and the Office of Aeronautics and Space Technology. It also describes NASA's Office of Commercial Programs, which funds the Centers for the Commercial Development of Space and the Small Business Innovation Research Program. This guide explains the roles played by NASA's eight field centers and the Jet Propulsion Laboratory, and gives a sampling of ongoing NASA-wide educational programs and services. Most importantly, this guide provides practical information in the form of names and telephone numbers of NASA contacts.

Setting up a cohort study in speech and language therapy: lessons from The UK Cleft Collective Speech and Language (CC-SL) study.

PubMed

Wren, Yvonne; Humphries, Kerry; Stock, Nicola Marie; Rumsey, Nichola; Lewis, Sarah; Davies, Amy; Bennett, Rhiannon; Sandy, Jonathan

2018-05-01

Efforts to increase the evidence base in speech and language therapy are often limited by methodological factors that have restricted the strength of the evidence to the lower levels of the evidence hierarchy. Where higher graded studies, such as randomized controlled trials, have been carried out, it has sometimes been difficult to obtain sufficient power to detect a potential effect of intervention owing to small sample sizes or heterogeneity in the participants. With certain clinical groups such as cleft lip and palate, systematic reviews of intervention studies have shown that there is no robust evidence to support the efficacy of any one intervention protocol over another. To describe the setting up of an observational clinical cohort study and to present this as an alternative design for answering research questions relating to prevalence, risk factors and outcomes from intervention. The Cleft Collective Speech and Language (CC-SL) study is a national cohort study of children born with cleft palate. Working in partnership with regional clinical cleft centres, a sample size of over 600 children and 600 parents is being recruited and followed up from birth to age 5 years. Variables being collected include demographic, psychological, surgical, hearing, and speech and language data. The process of setting up the study has led to the creation of a unique, large-scale data set which is available for researchers to access now and in future. As well as exploring predictive factors, the data can be used to explore the impact of interventions in relation to individual differences. Findings from these investigations can be used to provide information on sample criteria and definitions of intervention and dosage which can be used in future trials. The observational cohort study is a useful alternative design to explore questions around prevalence, risk factors and intervention for clinical groups where robust research data are not yet available. Findings from such a study can be used to guide service-delivery decisions and to determine power for future clinical trials. © 2017 Royal College of Speech and Language Therapists.

EMR Behavioral Curriculum and Student Record.

ERIC Educational Resources Information Center

Hartnett, John J.

Intended for use as a curriculum guide, a source for objectives for the individualized educational plan, and an evaluation instrument to measure handicapped students' learning, the guide lists sequences of developmental tasks. Tasks are outlined for primary, intermediate, and secondary levels in the following areas (sample subskills in…

INDUSTRIAL RADIOGRAPHY COURSE, INSTRUCTORS' GUIDE. VOLUME 2.

ERIC Educational Resources Information Center

Texas A and M Univ., College Station. Engineering Extension Service.

INFORMATION RELATIVE TO THE LESSON PLANS IN "INDUSTRIAL RADIOGRAPHY COURSE, INSTRUCTOR'S GUIDE, VOLUME I" (VT 003 565) IS PRESENTED ON 52 INFORMATION SHEETS INCLUDING THE SUBJECTS SHIELDING EQUATIONS AND LOGARITHMS, METAL PROPERTIES, FIELD TRIP INSTRUCTIONS FOR STUDENTS, WELDING SYMBOLS AND SIZES, SAMPLE REPORT FORMS, AND TYPICAL SHIPPING…

Advanced Tools Webinar Series Presents: Regulatory Issues and Case Studies of Advanced Tools

EPA Science Inventory

U.S. EPA has released A Guide for Assessing Biodegradation and Source Identification of Organic Ground Water Contaminants using Compound Specific Isotope Analysis (CSIA) [EPA 600/R-08/148 | December 2008 | www.epa.gov/ada]. The Guide provides recommendations for sample collecti...

Using a colorimeter to develop an intrinsic silicone shade guide for facial prostheses.

PubMed

Over, L M; Andres, C J; Moore, B K; Goodacre, C J; Muñoz, C A

1998-12-01

To determine if using CIE L*a*b* color measurements of white facial skin could be correlated to those of silicone shade samples that visually matched the skin. Secondly, to see if a correlation in color measurements could be achieved between the silicone shade samples and duplicated silicone samples made using a shade-guide color formula. A color booth was designed according to ASTM specifications, and painted using a Munsell Value 8 gray. A Minolta colorimeter was used to make facial skin measurements on 15 white adults. The skin color was duplicated using custom-shaded silicone samples. A 7-step wedge silicone shade guide was then fabricated, representing the commonly encountered thicknesses when fabricating facial prostheses. The silicone samples were then measured with the Minolta colorimeter. The readings were compared with the previous L*a*b* readings from the corresponding patient's skin measurements, and the relative color difference was then calculated. Silicone samples were fabricated and analyzed for three of the patients to determine if duplication of the visually matched silicone specimen was possible using the silicone color formula, and if the duplicates were visually and colorimetrically equivalent to each other. The color difference Delta E and chromaticity was calculated, and the data were analyzed using a coefficient-of-variation formula expressed by percent. A Pearson Product Moment Correlation Coefficient was performed to determine if a correlation existed between the skin and the silicone samples at the p < or = .05 level. The highest correlation was found in the b* dimension for silicone thicknesses of 1 to 4 mm. For silicone thicknesses of 6 to 10 mm, the highest correlation was found in the L* dimension. All three dimensions had positive correlations (R2 > 0), but only the 1-mm and 4-mm b* readings were very strong. Patient and silicone L*a*b* measurement results showed very little change in the a* axis, while the L* and b* measurements showed more change in their numbers, with changes in depth for all patient silicone samples. Delta E numbers indicated the lowest Delta E at the 1-mm depth and the highest Delta E at the 10-mm depth. All duplicated samples matched their original silicone samples to a degree that visual evaluation could not distinguish any color differences. Using volumetric measurements, a shade guide was developed for all 15 patients. There was good correlation between the patient's colorimeter measurements and the silicone samples, with the b* color dimension the most reproducible, followed by the L* and the a*. Silicone samples at 6, 8, and 10 mm matched the patient the best, and this study showed that silicone samples can be duplicated successfully if a good patient-silicone match is obtained. Rayon flocking fibers and liquid makeup are effective at matching facial prostheses and can be used to develop a simple shade guide for patient application.

Intraoperative imaging-guided cancer surgery: from current fluorescence molecular imaging methods to future multi-modality imaging technology.

PubMed

Chi, Chongwei; Du, Yang; Ye, Jinzuo; Kou, Deqiang; Qiu, Jingdan; Wang, Jiandong; Tian, Jie; Chen, Xiaoyuan

2014-01-01

Cancer is a major threat to human health. Diagnosis and treatment using precision medicine is expected to be an effective method for preventing the initiation and progression of cancer. Although anatomical and functional imaging techniques such as radiography, computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) have played an important role for accurate preoperative diagnostics, for the most part these techniques cannot be applied intraoperatively. Optical molecular imaging is a promising technique that provides a high degree of sensitivity and specificity in tumor margin detection. Furthermore, existing clinical applications have proven that optical molecular imaging is a powerful intraoperative tool for guiding surgeons performing precision procedures, thus enabling radical resection and improved survival rates. However, detection depth limitation exists in optical molecular imaging methods and further breakthroughs from optical to multi-modality intraoperative imaging methods are needed to develop more extensive and comprehensive intraoperative applications. Here, we review the current intraoperative optical molecular imaging technologies, focusing on contrast agents and surgical navigation systems, and then discuss the future prospects of multi-modality imaging technology for intraoperative imaging-guided cancer surgery.

Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology

PubMed Central

Chi, Chongwei; Du, Yang; Ye, Jinzuo; Kou, Deqiang; Qiu, Jingdan; Wang, Jiandong; Tian, Jie; Chen, Xiaoyuan

2014-01-01

Cancer is a major threat to human health. Diagnosis and treatment using precision medicine is expected to be an effective method for preventing the initiation and progression of cancer. Although anatomical and functional imaging techniques such as radiography, computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) have played an important role for accurate preoperative diagnostics, for the most part these techniques cannot be applied intraoperatively. Optical molecular imaging is a promising technique that provides a high degree of sensitivity and specificity in tumor margin detection. Furthermore, existing clinical applications have proven that optical molecular imaging is a powerful intraoperative tool for guiding surgeons performing precision procedures, thus enabling radical resection and improved survival rates. However, detection depth limitation exists in optical molecular imaging methods and further breakthroughs from optical to multi-modality intraoperative imaging methods are needed to develop more extensive and comprehensive intraoperative applications. Here, we review the current intraoperative optical molecular imaging technologies, focusing on contrast agents and surgical navigation systems, and then discuss the future prospects of multi-modality imaging technology for intraoperative imaging-guided cancer surgery. PMID:25250092

CT myocardial perfusion imaging: current status and future perspectives.

PubMed

Yang, Dong Hyun; Kim, Young-Hak

2017-07-01

Computed tomography myocardial perfusion (CTP) combined with coronary computed tomography angiography (CCTA) may constitute a "1-stop shop" for the noninvasive diagnosis of hemodynamically significant coronary stenosis during a single CT examination. CTP shows high diagnostic performance and provides incremental value over CCTA for the detection of hemodynamically significant coronary stenosis in patients with a high Agatston calcium score or coronary artery stents. Future studies should determine the optimal protocol and clinical value of CTP for guiding revascularization strategy and prognostication. In this article, we review the current status and future perspectives of CTP, focusing on technical considerations, clinical applications, and future research topics.

Understanding the relationship between religiosity and marriage: an investigation of the immediate and longitudinal effects of religiosity on newlywed couples.

PubMed

Sullivan, K T

2001-12-01

The association between religiosity and marital outcome has been repeatedly demonstrated, but a complete understanding of this relationship is hindered by limitations of theory and method. The purpose of the current study was to test 3 explanatory models by assessing 2 samples of newlywed couples. Findings indicated that religiosity was associated with attitudes toward divorce, commitment, and help seeking cross-sectionally. Longitudinal effects, however, were most consistent with a moderating model, wherein religiosity had a positive impact on husbands' and wives' marital satisfaction for couples with less neurotic husbands and a negative impact for couples with more neurotic husbands. Overall, the impact of religiosity was weak over the first 4 years of marriage. Theoretical propositions are offered to guide future research in delineating the types of marriages that may be most affected by religiosity.

Posttraumatic growth in post-surgical coronary artery bypass graft patients

PubMed Central

Waight, Catherine A; Sheridan, Judith; Tesar, Peter

2015-01-01

Recent research in posttraumatic growth has been applied to people with life-threatening illnesses to optimise recovery. There is a lack of research exploring posttraumatic growth in coronary artery bypass graft patients. This article describes the recovery experience of 14 coronary artery bypass graft patients (13 males and 1 female) at their first outpatient review post-surgery. Grounded theory analysis was used to develop a model of distinct and shared pathways to growth depending on whether patients were symptomatic or asymptomatic pre-coronary artery bypass graft. Outcomes of posttraumatic growth in this sample included action-based healthy lifestyle growth and two forms of cognitive growth: appreciation of life and new possibilities. The model of posttraumatic growth developed in this study may be helpful in guiding future research into promoting posttraumatic growth and behaviour change in coronary artery bypass graft patients. PMID:28070351

Machine processing of remotely sensed data; Proceedings of the Fifth Annual Symposium, Purdue University, West Lafayette, Ind., June 27-29, 1979

NASA Technical Reports Server (NTRS)

Tendam, I. M. (Editor); Morrison, D. B.

1979-01-01

Papers are presented on techniques and applications for the machine processing of remotely sensed data. Specific topics include the Landsat-D mission and thematic mapper, data preprocessing to account for atmospheric and solar illumination effects, sampling in crop area estimation, the LACIE program, the assessment of revegetation on surface mine land using color infrared aerial photography, the identification of surface-disturbed features through a nonparametric analysis of Landsat MSS data, the extraction of soil data in vegetated areas, and the transfer of remote sensing computer technology to developing nations. Attention is also given to the classification of multispectral remote sensing data using context, the use of guided clustering techniques for Landsat data analysis in forest land cover mapping, crop classification using an interactive color display, and future trends in image processing software and hardware.

Effect of Palagonite Dust Deposition on the Automated Detection of Carbonate Vis/NIR Spectra

NASA Technical Reports Server (NTRS)

Gilmore, Martha S.; Merrill, Matthew D.; Castano, Rebecca; Bornstein, Benjamin; Greenwood, James

2004-01-01

Currently Mars missions can collect more data than can be returned. Future rovers of increased mission lifetime will benefit from onboard autonomous data processing systems to guide the selection, measurement and return of scientifically important data. One approach is to train a neural net to recognize spectral reflectance characteristics of minerals of interest. We have developed a carbonate detector using a neural net algorithm trained on 10,000 synthetic Vis/NIR (350-2500 nm) spectra. The detector was able to correctly identify carbonates in the spectra of 30 carbonate and noncarbonate field samples with 100% success. However, Martian dust coatings strongly affect the spectral characteristics of surface rocks potentially masking the underlying substrate rock. In this experiment, we measure Vis/NIR spectra of calcite coated with different thicknesses of palagonite dust and evaluate the performance of the carbonate detector.

Farm animal practitioners' views on their use and expectations of veterinary diagnostic laboratories.

PubMed

Robinson, P A; Epperson, W B

2013-05-11

Diagnostic sampling of farm animals by private veterinary practitioners can be an important contributing factor towards the discovery of emerging and exotic diseases. This focus group study of farm animal practitioners in Northern Ireland investigated their use and expectations of diagnostic veterinary laboratories, and elicited their opinions on the role of the private practitioner in veterinary surveillance and the protection of rural public health. The veterinarians were enthusiastic users of diagnostic laboratories, and regarded their own role in surveillance as pivotal. They attached great importance to their veterinary public health duties, and called for more collaboration with their medical general practitioner counterparts. The findings of this research can be used to guide future development of veterinary diagnostic services; provide further insights into the mechanics of scanning surveillance; and measure progress towards a 'One Health' approach between veterinarians and physicians in one geographical region of the UK.

Influencing factors on cervical cancer screening from the Kurdish women's perspective: A qualitative study.

PubMed

Rasul, V H; Cheraghi, M A; Behboodi Moqadam, Z

2015-01-01

Aim: This study was aimed to explore and describe the Kurdish women's perception of cervical cancer screening. Methods: A qualitative design based on a conventional content analysis approach. Purposive sampling was applied to 19 women chosen, who had a Pap smear or refused to have one. The study was performed in the Kurdistan Region, Iraq. Semi-structure din-depth individual interviews were carried out to collect data. Results: Four main themes including conflict, belief, and awareness about cervical cancer screening and socio-cultural factors emerged during data analysis Conclusions: Cervical cancer has a high mortality rate in the developing countries. However, only a few Kurdish women participated in the cervical cancer screening in the Kurdistan Region, Iraq. Understanding the factors associated with the women's perception of cervical cancer could guide future educational planning and clinical interventions improve the cervical cancer screening.

Influencing factors on cervical cancer screening from the Kurdish women’s perspective: A qualitative study

PubMed Central

Rasul, VH; Cheraghi, MA; Behboodi Moqadam, Z

2015-01-01

Aim:This study was aimed to explore and describe the Kurdish women’s perception of cervical cancer screening. Methods: A qualitative design based on a conventional content analysis approach. Purposive sampling was applied to 19 women chosen, who had a Pap smear or refused to have one. The study was performed in the Kurdistan Region, Iraq. Semi-structure din-depth individual interviews were carried out to collect data. Results: Four main themes including conflict, belief, and awareness about cervical cancer screening and socio-cultural factors emerged during data analysis Conclusions: Cervical cancer has a high mortality rate in the developing countries. However, only a few Kurdish women participated in the cervical cancer screening in the Kurdistan Region, Iraq. Understanding the factors associated with the women’s perception of cervical cancer could guide future educational planning and clinical interventions improve the cervical cancer screening. PMID:28255397

Seat and seatbelt accommodation in fire apparatus: Anthropometric aspects

PubMed Central

Hsiao, Hongwei; Whitestone, Jennifer; Wilbur, Michael; Lackore, J. Roger; Routley, J. Gordon

2015-01-01

This study developed anthropometric information on U.S. firefighters to guide fire-apparatus seat and seatbelt designs and future standards development. A stratified sample of 863 male and 88 female firefighters across the U.S. participated in the study. The study results suggested 498 mm in width, 404 mm in depth, and 365–476 mm in height for seat pans; 429–522 mm in width and 542 mm in height for seat back; 871 mm in height for head support; a seat space of 733 mm at shoulder and 678 mm at hip; and a knee/leg clearance of 909 mm in fire truck cab. Also, 1520 mm of lap belt web effective length and 2828 mm of lap-and-shoulder belt web effective length were suggested. These data for firetruck seats and seatbelts provide a foundation for fire apparatus manufacturers and standards committees to improve firefighter seat designs and seatbelt usage compliance. PMID:26154212

Promoting recovery: service user and staff perceptions of resilience provided by a new Early Intervention in Psychosis service.

PubMed

Morton, Adrian; Fairhurst, Alicia; Ryan, Rebecca

2010-02-01

The principles and practice of recovery are guiding many changes in mental health service provision. As a new Early Intervention in Psychosis (EIP) service, we were interested in finding out if both staff and users perceive the service as promoting resilience and in turn, recovery. A naturalistic sample of service users and staff completed the Organizational Climate questionnaire to assess the degree to which the service promotes resilience in overcoming a first episode psychosis. The results indicated that both staff and service users similarly perceive the service as positively supporting resilience. The one exception was the staff rated the 'available resources to meet people's needs' as less than service users. The positive rating of resilience indicated that the service is working in a manner consistent with a recovery orientation. The results will act as a benchmark to compare with both other EIP services and future performance.

Cost-effectiveness of alternative outpatient pelvic inflammatory disease treatment strategies.

PubMed

Smith, Kenneth J; Ness, Roberta B; Wiesenfeld, Harold C; Roberts, Mark S

2007-12-01

Effectiveness differences between outpatient pelvic inflammatory disease (PID) treatment regimens are uncertain, but significant differences in cost exist. To examine the influence of antibiotic costs on PID therapy cost-effectiveness. The authors used a Markov decision model to estimate the cost-effectiveness of recommended antibiotic regimens for PID and performed a value of information analysis to guide future research. Antibiotic costs vary between USD 43 and USD188. Pairwise comparisons, assuming a hypothetical 1% relative risk reduction in PID complications with the more expensive regimen, showed economically reasonable cost-effectiveness ratios. Value of information and sample size considerations support further investigation to detect 10% PID complication rate differences between regimens with >or=USD 50 cost differences. Within the cost range of recommended regimens, use of more expensive antibiotics would be economically reasonable if relatively small decreases in PID complication rates exist. Further investigation of effectiveness differences between regimens is needed.

Molecular genetics of childhood, adolescent and young adult non-Hodgkin lymphoma.

PubMed

Miles, Rodney R; Shah, Rikin K; Frazer, J Kimble

2016-05-01

Molecular genetic abnormalities are ubiquitous in non-Hodgkin lymphoma (NHL), but genetic changes are not yet used to define specific lymphoma subtypes. Certain recurrent molecular genetic abnormalities in NHL underlie molecular pathogenesis and/or are associated with prognosis or represent potential therapeutic targets. Most molecular genetic studies of B- and T-NHL have been performed on adult patient samples, and the relevance of many of these findings for childhood, adolescent and young adult NHL remains to be demonstrated. In this review, we focus on NHL subtypes that are most common in young patients and emphasize features actually studied in younger NHL patients. This approach highlights what is known about NHL genetics in young patients but also points to gaps that remain, which will require cooperative efforts to collect and share biological specimens for genomic and genetic analyses in order to help predict outcomes and guide therapy in the future. © 2016 John Wiley & Sons Ltd.

Minimal residual disease in chronic lymphocytic leukaemia.

PubMed

García Vela, José Antonio; García Marco, José Antonio

2018-02-23

Minimal residual disease (MRD) assessment is an important endpoint in the treatment of chronic lymphocytic leukaemia (CLL). It is highly predictive of prolonged progression-free survival (PFS) and overall survival and could be considered a surrogate for PFS in the context of chemoimmunotherapy based treatment. Evaluation of MRD level by flow cytometry or molecular techniques in the era of the new BCR and Bcl-2 targeted inhibitors could identify the most cost-effective and durable treatment sequencing. A therapeutic approach guided by the level of MRD might also determine which patients would benefit from an early stop or consolidation therapy. In this review, we discuss the different MRD methods of analysis, which source of tumour samples must be analysed, the future role of the detection of circulating tumour DNA, and the potential role of MRD negativity in clinical practice in the modern era of CLL therapy. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.