Sample records for guided instruction cgi

  1. A Living Metaphor of Differentiation: A Meta-Ethnography of Cognitively Guided Instruction in the Elementary Classroom

    ERIC Educational Resources Information Center

    Baker, Katherine; Harter, Meghan Evelynne

    2015-01-01

    This meta-ethnography explores qualitative studies around the Cognitively Guided Instruction (CGI) framework of mathematics and illustrates how CGI epitomizes differentiation. The meta-ethnographic process is used to synthesize CGI as differentiation, specifically within the elementary mathematics classroom. Thomas P. Carpenter is credited as one…

  2. Measurement in the Service of Mathematics Education Research: The Case of Cognitively Guided Instruction

    ERIC Educational Resources Information Center

    Helding, Brandon Alan

    2010-01-01

    The purpose of this dissertation is to demonstrate one iterate of a process for developing a measurement instrument for student knowledge within educational interventions. Student mathematical knowledge is framed within Cognitively Guided Instruction (CGI) and its tenets. That is, the construct underlying the measurement instrument corresponded…

  3. The Effect of Cognitively Guided Instruction on Primary Students' Math Achievement, Problem-Solving Abilities and Teacher Questioning

    ERIC Educational Resources Information Center

    Medrano, Juan

    2012-01-01

    The purpose of this study is to impact the teaching and learning of math of 2nd through 4th grade math students at Porfirio H. Gonzales Elementary School. The Cognitively Guided Instruction (CGI) model serves as the independent variable for this study. Its intent is to promote math instruction that emphasizes problem-solving to a greater degree…

  4. The Effects of Cognitively Guided Instruction on Mathematics Achievement of Second Grade Children

    ERIC Educational Resources Information Center

    Hendricks, Cynthia

    2013-01-01

    In 2010, 6% of students in the United States were performing at an advanced level in mathematics. During the previous year, the United States produced over 987,000 low math achievers. The theoretical foundations of this research project study were found in Cognitively Guided Instruction (CGI). The research problem addressed in this study is the…

  5. "I like It Instead of Maths": How Pupils with Moderate Learning Difficulties in Scottish Primary Special Schools Intuitively Solved Mathematical Word Problems

    ERIC Educational Resources Information Center

    Moscardini, Lio

    2010-01-01

    This study by Lio Moscardini of the University of Strathclyde shows how a group of 24 children in three Scottish primary schools for pupils with moderate learning difficulties responded to word problems following their teachers' introduction to the principles of Cognitively Guided Instruction (CGI). CGI is a professional development programme in…

  6. Changes in One Teacher's Proportional Reasoning Instruction after Participating in a CGI Professional Development Workshop

    ERIC Educational Resources Information Center

    de la Cruz, Jessica A.

    2016-01-01

    This study examined how one teacher used research-based knowledge of how adolescents think about proportions. Observations, interviews, document collection, and a workshop intervention were utilized. The design of the workshop was inspired by the cognitively guided instruction studies and its purpose was to explore the research findings on…

  7. Modification of the Clinical Global Impressions (CGI) Scale for use in bipolar illness (BP): the CGI-BP.

    PubMed

    Spearing, M K; Post, R M; Leverich, G S; Brandt, D; Nolen, W

    1997-12-05

    The Clinical Global Impressions Scale (CGI) was modified specifically for use in assessing global illness severity and change in patients with bipolar disorder. Criticisms of the original CGI were addressed by correcting inconsistencies in scaling, identifying time frames for comparison, clarifying definitions of illness severity and change, and separating out assessment of treatment side effects from illness improvement during treatment. A Detailed User's Guide was developed to train clinicians in the use of the new CGI-Bipolar Version (CGI-BP) for rating severity of manic and depressive episodes and the degree of change from the immediately preceding phase and from the worst phase of illness. The revised scale and manual provide a focused set of instructions to facilitate the reliability of these ratings of mania, depression, and overall bipolar illness during treatment of an acute episode or in longer-term illness prophylaxis. Interrater reliability of the scale was demonstrated in preliminary analyses. Thus, the modified CGI-BP is anticipated to be more useful than the original CGI in studies of bipolar disorder.

  8. Incidental Testicular Irradiation From Prostate IMRT: It All Adds Up

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    King, Christopher R., E-mail: crking@stanford.ed; Maxim, Peter G.; Hsu, Annie

    Purpose: To identify the technical aspects of image-guided intensity-modulated radiation therapy (IMRT) for localized prostate cancer that could result in a clinically meaningful incidental dose to the testes. Methods and Materials: We examined three sources that contribute incidental dose to the testes, namely, from internal photon scattering from IMRT small field and large pelvic nodal fields with 6 or 15 MV, from neutrons when >10-MV photons are used, and from daily image-guided fiducial-based portal imaging. Using clinical data from 10 patients who received IMRT for prostate cancer, and thermo-luminescent dosimeter measurements in phantom, we estimated the dose to the testesmore » from each of these sources. Results: A mean testicular dose of 172 and 220 cGy results from internal photon scatter for pelvic nodal fields and 68 and 93 cGy for prostate-only fields, for 6- and 15-MV energies, respectively. For 15-MV photon energies, the mean testicular dose from neutrons is 60 cGy for pelvic fields and 31 cGy for prostate-only fields. From daily portal MV image guidance, the testes-in-field mean dose is 350 cGy, whereas the testes-out-of-field scatter dose is 16 cGy. Dosimetric comparisons between IMRT using 6-MV and 15-MV photon energies are not significantly different. Worst-case scenarios can potentially deliver cumulative incidental mean testicular doses of 630 cGy, whereas best-case scenarios can deliver only 84 cGy. Conclusions: Incidental dose to the testes from prostate IMRT can be minimized by opting to restrict the use of elective pelvic nodal fields, by choosing photon energies <10 MV, and by using the smallest port sizes necessary for daily image guidance.« less

  9. Multifractionated image-guided and stereotactic intensity-modulated radiotherapy of paraspinal tumors: a preliminary report.

    PubMed

    Yamada, Yoshiya; Lovelock, D Michael; Yenice, Kamil M; Bilsky, Mark H; Hunt, Margaret A; Zatcky, Joan; Leibel, Steven A

    2005-05-01

    The use of image-guided and stereotactic intensity-modulated radiotherapy (IMRT) techniques have made the delivery of high-dose radiation to lesions within close proximity to the spinal cord feasible. This report presents clinical and physical data regarding the use of IMRT coupled with noninvasive body frames (stereotactic and image-guided) for multifractionated radiotherapy. The Memorial Sloan-Kettering Cancer Center (Memorial) stereotactic body frame (MSBF) and Memorial body cradle (MBC) have been developed as noninvasive immobilizing devices for paraspinal IMRT using stereotactic (MSBF) and image-guided (MBC) techniques. Patients were either previously irradiated or prescribed doses beyond spinal cord tolerance (54 Gy in standard fractionation) and had unresectable gross disease involving the spinal canal. The planning target volume (PTV) was the gross tumor volume with a 1 cm margin. The PTV was not allowed to include the spinal cord contour. All treatment planning was performed using software developed within the institution. Isocenter verification was performed with an in-room computed tomography scan (MSBF) or electronic portal imaging devices, or both. Patients were followed up with serial magnetic resonance imaging every 3-4 months, and no patients were lost to follow-up. Kaplan-Meier statistics were used for analysis of clinical data. Both the MSBF and MBC were able to provide setup accuracy within 2 mm. With a median follow-up of 11 months, 35 patients (14 primary and 21 secondary malignancies) underwent treatment. The median dose previously received was 3000 cGy in 10 fractions. The median dose prescribed for these patients was 2000 cGy/5 fractions (2000-3000 cGy), which provided a median PTV V100 of 88%. In previously unirradiated patients, the median prescribed dose was 7000 cGy (5940-7000 cGy) with a median PTV V100 of 90%. The median Dmax to the cord was 34% and 68% for previously irradiated and never irradiated patients, respectively. More than 90% of patients experienced palliation from pain, weakness, or paresthesia; 75% and 81% of secondary and primary lesions, respectively, exhibited local control at the time of last follow-up. No cases of radiation-induced myelopathy or radiculopathy have thus far been encountered. Precision stereotactic and image-guided paraspinal IMRT allows the delivery of high doses of radiation in multiple fractions to tumors within close proximity to the spinal cord while respecting cord tolerance. Although preliminary, the clinical results are encouraging.

  10. Interactive Economics Instruction with Java and CGI.

    ERIC Educational Resources Information Center

    Gerdes, Geoffrey R.

    2000-01-01

    States that this Web site is based on the conviction that Web-based materials must contain interactive modules to achieve value beyond that obtained by conventional media. Discusses three applets that can be reached at the homepage of the Web site by selecting the Java applets link. (CMK)

  11. Temporary organ displacement coupled with image-guided, intensity-modulated radiotherapy for paraspinal tumors

    PubMed Central

    2013-01-01

    Background To investigate the feasibility and dosimetric improvements of a novel technique to temporarily displace critical structures in the pelvis and abdomen from tumor during high-dose radiotherapy. Methods Between 2010 and 2012, 11 patients received high-dose image-guided intensity-modulated radiotherapy with temporary organ displacement (TOD) at our institution. In all cases, imaging revealed tumor abutting critical structures. An all-purpose drainage catheter was introduced between the gross tumor volume (GTV) and critical organs at risk (OAR) and infused with normal saline (NS) containing 5-10% iohexol. Radiation planning was performed with the displaced OARs and positional reproducibility was confirmed with cone-beam CT (CBCT). Patients were treated within 36 hours of catheter placement. Radiation plans were re-optimized using pre-TOD OARs to the same prescription and dosimetrically compared with post-TOD plans. A two-tailed permutation test was performed on each dosimetric measure. Results The bowel/rectum was displaced in six patients and kidney in four patients. One patient was excluded due to poor visualization of the OAR; thus 10 patients were analyzed. A mean of 229 ml (range, 80–1000) of NS 5-10% iohexol infusion resulted in OAR mean displacement of 17.5 mm (range, 7–32). The median dose prescribed was 2400 cGy in one fraction (range, 2100–3000 in 3 fractions). The mean GTV Dmin and PTV Dmin pre- and post-bowel TOD IG-IMRT dosimetry significantly increased from 1473 cGy to 2086 cGy (p=0.015) and 714 cGy to 1214 cGy (p=0.021), respectively. TOD increased mean PTV D95 by 27.14% of prescription (p=0.014) while the PTV D05 decreased by 9.2% (p=0.011). TOD of the bowel resulted in a 39% decrease in mean bowel Dmax (p=0.008) confirmed by CBCT. TOD of the kidney significantly decreased mean kidney dose and Dmax by 25% (0.022). Conclusions TOD was well tolerated, reproducible, and facilitated dose escalation to previously radioresistant tumors abutting critical structures while minimizing dose to OARs. PMID:23800073

  12. Identifying clinically meaningful symptom response cut-off values on the SANS in predominant negative symptoms.

    PubMed

    Levine, Stephen Z; Leucht, Stefan

    2013-04-01

    The treatment and measurement of negative symptoms are currently at issue in schizophrenia, but the clinical meaning of symptom severity and change is unclear. To offer a clinically meaningful interpretation of severity and change scores on the Scale for the Assessment of Negative Symptoms (SANS). Patients were intention-to-treat participants (n=383) in two double-blind randomized placebo-controlled clinical trials that compared amisulpride with placebo for the treatment of predominant negative symptoms. Equipercentile linking was used to examine extrapolation from (a) CGI-S to SANS severity ratings, and (b) CGI-I to SANS percentage change (n=383). Linking was conducted at baseline, 8-14 days, 28-30 days, and 56-60 days of the trials. Across visits, CGI-S ratings of 'not ill' linked to SANS scores of 0-13, and ranged to 'extreme' ratings that linked to SANS scores of 102-105. The relationship between the CGI-S and the SANS severity scores assumed a linear trend (1=0-13, 2=15-56, 3=37-61, 4=49-66, 5=63-75, 6=79-89, 7=102-105). Similarly the relationship between CGI-I ratings and SANS percentage change followed a linear trend. For instance, CGI-I ratings of 'very much improved' were linked to SANS percent changes of -90 to -67, 'much improved' to -50 to -42, and 'minimally improved' to -21 to -13. The current results uniquely contribute to the debate surrounding negative symptoms by providing clinical meaning to SANS severity and change scores and so offer direction regarding clinically meaningful response cut-off scores to guide treatment targets of predominant negative symptoms. Copyright © 2013 Elsevier B.V. All rights reserved.

  13. The impact of histology and delivered dose on local control of spinal metastases treated with stereotactic radiosurgery.

    PubMed

    Yamada, Yoshiya; Katsoulakis, Evangelia; Laufer, Ilya; Lovelock, Michael; Barzilai, Ori; McLaughlin, Lily A; Zhang, Zhigang; Schmitt, Adam M; Higginson, Daniel S; Lis, Eric; Zelefsky, Michael J; Mechalakos, James; Bilsky, Mark H

    2017-01-01

    OBJECTIVE An analysis of factors contributing to durable radiographic control of spinal metastases was undertaken, drawing from a large single-institution database in an attempt to elucidate indications and dose requirements for successful treatment. METHODS All patients treated at a single institution with stereotactic radiosurgery (SRS) of the spine as first-line therapy were assessed for local progression of the treated site, defined as radiographic enlargement of the treated tumor and/or biopsy-proven evidence of active tumor cells. All patients were followed with CT, PET, or MR imaging every 3-6 months until death. Treatment decisions were made by a multidisciplinary team of radiation oncologists, neurosurgeons, and neuroradiologists. Target volumes were defined according to the international consensus guidelines and were reviewed in a multidisciplinary conference. Image-guided techniques and intensity modulation were used for every case. The tumor's histological type, gross tumor volume (GTV), dose that covers 95% of the GTV (GTV D95), percentage of GTV covered by 95% of the prescribed dose (GTV V95), planning target volume (PTV), dose that covers 95% of the PTV (PTV D95), and percentage of PTV covered by 95% of the prescribed dose (PTV V95) were analyzed for significance in relation to local control, based on time to local progression. RESULTS A total of 811 lesions were treated in 657 patients between 2003 and 2015 at a single institution. The mean follow-up and overall survival for the entire cohort was 26.9 months (range 2-141 months). A total of 28 lesions progressed and the mean time to failure was 26 months (range 9.7-57 months). The median prescribed dose was 2400 cGy (range 1600-2600 cGy). Both GTV D95 and PTV D95 were highly significantly associated with local failure in univariate analysis, but GTV and PTV and histological type did not reach statistical significance. The median GTV D95 for the cohort equal to or above the GTV D95 1830 cGy cut point (high dose) was 2356 cGy, and it was 1709 cGy for the cohort of patients who received less than 1830 cGy (low dose). In terms of PTV D95, the median dose for those equal to or above the cut point of 1740 cGy (high dose) was 2233 cGy, versus 1644 cGy for those lesions below the PTV D95 cut point of 1740 cGy (low dose). CONCLUSIONS High-dose single-session SRS provides durable long-term control, regardless of the histological findings or tumor size. In this analysis, the only significant factors predictive of local control were related to the actual dose of radiation given. Although the target volumes were well treated with the intended dose, those lesions irradiated to higher doses (median GTV D95 2356 cGy, minimum 1830 cGy) had a significantly higher probability of durable local control than those treated with lower doses (median PTV D95 2232 cGy, minimum of 1740 cGy) (p < 0.001). Patients in the high-dose cohort had a 2% cumulative rate of local failure. Histological findings were not associated with local failure, suggesting that radioresistant histological types benefit in particular from radiosurgery. For patients with a favorable prognosis, a higher dose of SRS is important for long-term outcomes.

  14. The impact of histology and delivered dose on local control of spinal metastases treated with stereotactic radiosurgery

    PubMed Central

    Yamada, Yoshiya; Katsoulakis, Evangelia; Laufer, Ilya; Lovelock, Michael; Barzilai, Ori; McLaughlin, Lily A.; Zhang, Zhigang; Schmitt, Adam M.; Higginson, Daniel S.; Lis, Eric; Zelefsky, Michael J.; Mechalakos, James; Bilsky, Mark H.

    2017-01-01

    Objective An analysis of factors contributing to durable radiographic control of spinal metastases was undertaken, drawing from a large single-institution database in an attempt to elucidate indications and dose requirements for successful treatment. Methods All patients treated at a single institution with stereotactic radiosurgery (SRS) of the spine as first-line therapy were assessed for local progression of the treated site, defined as radiographic enlargement of the treated tumor and/or biopsy-proven evidence of active tumor cells. All patients were followed with CT, PET, or MR imaging every 3–6 months until death. Treatment decisions were made by a multidisciplinary team of radiation oncologists, neurosurgeons, and neuroradiologists. Target volumes were defined according to the international consensus guidelines and were reviewed in a multidisciplinary conference. Image-guided techniques and intensity modulation were used for every case. The tumor’s histological type, gross tumor volume (GTV), dose that covers 95% of the GTV (GTV D95), percentage of GTV covered by 95% of the prescribed dose (GTV V95), planning target volume (PTV), dose that covers 95% of the PTV (PTV D95), and percentage of PTV covered by 95% of the prescribed dose (PTV V95) were analyzed for significance in relation to local control, based on time to local progression. Results A total of 811 lesions were treated in 657 patients between 2003 and 2015 at a single institution. The mean follow-up and overall survival for the entire cohort was 26.9 months (range 2–141 months). A total of 28 lesions progressed and the mean time to failure was 26 months (range 9.7–57 months). The median prescribed dose was 2400 cGy (range 1600–2600 cGy). Both GTV D95 and PTV D95 were highly significantly associated with local failure in univariate analysis, but GTV and PTV and histological type did not reach statistical significance. The median GTV D95 for the cohort equal to or above the GTV D95 1830 cGy cut point (high dose) was 2356 cGy, and it was 1709 cGy for the cohort of patients who received less than 1830 cGy (low dose). In terms of PTV D95, the median dose for those equal to or above the cut point of 1740 cGy (high dose) was 2233 cGy, versus 1644 cGy for those lesions below the PTV D95 cut point of 1740 cGy (low dose). Conclusions High-dose single-session SRS provides durable long-term control, regardless of the histological findings or tumor size. In this analysis, the only significant factors predictive of local control were related to the actual dose of radiation given. Although the target volumes were well treated with the intended dose, those lesions irradiated to higher doses (median GTV D95 2356 cGy, minimum 1830 cGy) had a significantly higher probability of durable local control than those treated with lower doses (median PTV D95 2232 cGy, minimum of 1740 cGy) (p < 0.001). Patients in the high-dose cohort had a 2% cumulative rate of local failure. Histological findings were not associated with local failure, suggesting that radioresistant histological types benefit in particular from radiosurgery. For patients with a favorable prognosis, a higher dose of SRS is important for long-term outcomes. PMID:28041329

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Park, J; Kim, J; Park, S

    Purpose: To investigate exposure outside the treatment field when treating breast cancer with tri-Co-60 magnetic resonance (MR) image guided radiation therapy (IGRT) system. Methods: A total of 7 patients who treated with accelerated partial breast irradiation (APBI) technique were selected prospectively for this study (prescription dose = 38.5 Gy in 10 fractions). Every patient treated with two plans, one was an initial plan and the other was an adaptive plan generated after finishing 5 fractions (a total of 14 plans). Every plan was calculated with and without magnetic field in the treatment planning system. The EBT3 films were attached onmore » the front and the back of 1 cm bolus, and then it was placed on the patient body vertically to cover patient’s jaw and shoulder. After measurements, the maximum point dose and the mean dose of whole area of EBT3 film were acquired. Results: In the treatment plan with magnetic field, low dose stream outside the patient body was observed, almost reaching the patient’s jaw or shoulder, while it was not observed without magnetic field. The average values of the measured maximum and mean doses at the front of bolus were 30.1 ± 11.1 cGy (7.8% of the daily dose) and 14.7 ± 3.3 cGy (3.8%), respectively. At the back of bolus, those values were 6.0 ± 1.9 cGy (1.6%) and 5.1 ± 1.6 cGy (1.3%), respectively. The largest maximum dose at the front was 54.2 cGy (14.1%) while it was 20.7 cGy (5.4%) at the back. The average decrease of the maximum dose by the bolus was 24.0 ± 11.0 cGy. Conclusion: Due to magnetic field, dose stream outside the patient body can be generated during breast cancer treatment with the tri-Co-60 MR-IGRT system. Since this dose stream irradiated skin outside the treatment field, it should be shielded. This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No. 2015R1C1A1A01054192).« less

  16. TH-CD-BRA-11: Implementation and Evaluation of a New 3D Dosimetry Protocol for Validating MRI Guided Radiation Therapy Treatments

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mein, S; Rankine, L; Department of Radiation Oncology, Washington University School of Medicine

    Purpose: To develop, evaluate and apply a novel high-resolution 3D remote dosimetry protocol for validation of MRI guided radiation therapy treatments (MRIdian by ViewRay™). We demonstrate the first application of the protocol (including two small but required new correction terms) utilizing radiochromic 3D plastic PRESAGE™ with optical-CT readout. Methods: A detailed study of PRESAGE™ dosimeters (2kg) was conducted to investigate the temporal and spatial stability of radiation induced optical density change (ΔOD) over 8 days. Temporal stability was investigated on 3 dosimeters irradiated with four equally-spaced square 6MV fields delivering doses between 10cGy and 300cGy. Doses were imaged (read-out) bymore » optical-CT at multiple intervals. Spatial stability of ΔOD response was investigated on 3 other dosimeters irradiated uniformly with 15MV extended-SSD fields with doses of 15cGy, 30cGy and 60cGy. Temporal and spatial (radial) changes were investigated using CERR and MATLAB’s Curve Fitting Tool-box. A protocol was developed to extrapolate measured ΔOD readings at t=48hr (the typical shipment time in remote dosimetry) to time t=1hr. Results: All dosimeters were observed to gradually darken with time (<5% per day). Consistent intra-batch sensitivity (0.0930±0.002 ΔOD/cm/Gy) and linearity (R2=0.9996) was observed at t=1hr. A small radial effect (<3%) was observed, attributed to curing thermodynamics during manufacture. The refined remote dosimetry protocol (including polynomial correction terms for temporal and spatial effects, CT and CR) was then applied to independent dosimeters irradiated with MR-IGRT treatments. Excellent line profile agreement and 3D-gamma results for 3%/3mm, 10% threshold were observed, with an average passing rate 96.5%± 3.43%. Conclusion: A novel 3D remote dosimetry protocol is presented capable of validation of advanced radiation treatments (including MR-IGRT). The protocol uses 2kg radiochromic plastic dosimeters read-out by optical-CT within a week of treatment. The protocol requires small corrections for temporal and spatially-dependent behaviors observed between irradiation and readout.« less

  17. Time delays in flight simulator visual displays

    NASA Technical Reports Server (NTRS)

    Crane, D. F.

    1980-01-01

    It is pointed out that the effects of delays of less than 100 msec in visual displays on pilot dynamic response and system performance are of particular interest at this time because improvements in the latest computer-generated imagery (CGI) systems are expected to reduce CGI displays delays to this range. Attention is given to data which quantify the effects of display delays in the range of 0-100 msec on system stability and performance, and pilot dynamic response for a particular choice of aircraft dynamics, display, controller, and task. The conventional control system design methods are reviewed, the pilot response data presented, and data for long delays, all suggest lead filter compensation of display delay. Pilot-aircraft system crossover frequency information guides compensation filter specification.

  18. Cataloging Guide for Instructional Materials Used in Livonia Public Schools Instructional Materials Centers.

    ERIC Educational Resources Information Center

    Livonia Public Schools, MI.

    This working guide for Livonia's Public Schools provides detailed instructions in preparing and handling catalog cards, a supplemental cataloging and classification guide, and typing rules for technical processing. Standard abbreviations are given for making classification entries, and separate cataloging instructions are given for charts,…

  19. Testicular Doses in Image-Guided Radiotherapy of Prostate Cancer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Deng Jun, E-mail: jun.deng@yale.edu; Chen Zhe; Yu, James B.

    Purpose: To investigate testicular doses contributed by kilovoltage cone-beam computed tomography (kVCBCT) during image-guided radiotherapy (IGRT) of prostate cancer. Methods and Materials: An EGS4 Monte Carlo code was used to calculate three-dimensional dose distributions from kVCBCT on 3 prostate cancer patients. Absorbed doses to various organs were compared between intensity-modulated radiotherapy (IMRT) treatments and kVCBCT scans. The impact of CBCT scanning mode, kilovoltage peak energy (kVp), and CBCT field span on dose deposition to testes and other organs was investigated. Results: In comparison with one 10-MV IMRT treatment, a 125-kV half-fan CBCT scan delivered 3.4, 3.8, 4.1, and 5.7 cGymore » to the prostate, rectum, bladder, and femoral heads, respectively, accounting for 1.7%, 3.2%, 3.2%, and 8.4% of megavoltage photon dose contributions. However, the testes received 2.9 cGy from the same CBCT scan, a threefold increase as compared with 0.7 cGy received during IMRT. With the same kVp, full-fan mode deposited much less dose to organs than half-fan mode, ranging from 9% less for prostate to 69% less for testes, except for rectum, where full-fan mode delivered 34% more dose. As photon beam energy increased from 60 to 125 kV, kVCBCT-contributed doses increased exponentially for all organs, irrespective of scanning mode. Reducing CBCT field span from 30 to 10 cm in the superior-inferior direction cut testicular doses from 5.7 to 0.2 cGy in half-fan mode and from 1.5 to 0.1 cGy in full-fan mode. Conclusions: Compared with IMRT, kVCBCT-contributed doses to the prostate, rectum, bladder, and femoral heads are clinically insignificant, whereas dose to the testes is threefold more. Full-fan CBCT usually deposits much less dose to organs (except for rectum) than half-fan mode in prostate patients. Kilovoltage CBCT-contributed doses increase exponentially with photon beam energy. Reducing CBCT field significantly cuts doses to testes and other organs.« less

  20. The Effect of Guided Self-Reflection on Teachers' Technology Use

    ERIC Educational Resources Information Center

    Farber, Susan

    2010-01-01

    The purpose of this study was to pilot an instructional planning tool grounded in guided self-reflection on the instructional planning practices and instructional behaviors of a small sample of teachers. I designed the instructional planning tool, which was named the Informed Technology Integration Guide (ITIG). Participants used the instructional…

  1. A Home for Pearl. A Videotape Series about Wildlife Habitat for Elementary Students. Instructional Guide.

    ERIC Educational Resources Information Center

    Lambeth, Ellen; Westervelt, Miriam O.

    This instructional guide (accompanied by a video) teaches children from ages 6 to 12 about wildlife habitats. The instructional guide is divided into four parts and consists of supplementary activities to enhance the video. Each section of the guide provides an overview, objectives, story summary, key words in the video, discussion questions,…

  2. Density characterization of radiochromic film through source axis distance (SAD) technique in linac with slab phantom for radiotherapy applications

    NASA Astrophysics Data System (ADS)

    Hariani, Yousida; Haris, Bambang

    2017-05-01

    Characterization of radiochromic film density is accomplished through Source Axis Distance (SAD) technique in a slab phantom Linac with various depths and breadths of field. Type of the film used is gafchromic RTQA2. The dose of radiation exposure of the film may cause changes in the film density. This research aims to determine the relation between the density and the dose depth through the characteristic of curves to identify the depth of the dose and particular breadth of the field as a reference for the dose of radiotherapy patients. The result shows that the higher the dose is absorbed, the darker the film will be, yet the lower the density is obtained. The dose depth is determined by measuring the amount of dose received at various depths and breadths of field using film that is placed on the slab phantom with 6 MV linac radiation and dose of 300 cGy. The variation of the depth at 1.5 cm; 4 cm; 6 cm; 8 cm; 10 cm, the field size at 4 × 4 cm2, and the dose depth at 359.7 cGy; 315.3 cGy; 281.4 cGy; 241.2 cGy; 220.5 cGy were settled. The field size 6 × 6 cm2 takes the dose depth 354.6 cGy; 314.1 cGy; 282.6 cGy; 244.5 cGy; 224.7 cGy. The field size 8 × 8 cm2 takes the dose depth 351.6 cGy; 313 cGy; 283.8 cGy; 247.2 cGy; 228 cGy. The field size 10 × 10 cm2 takes the dose depth 348.9 cGy; 342.6 cGy; 248.4 cGy; 249.6 cGy; 231 cGy.

  3. Clozapine for Drug-Refractory Irritability in Individuals with Developmental Disability.

    PubMed

    Wink, Logan K; Badran, Ismail; Pedapati, Ernest V; Sorensen, Rena; Benton, Stacy C; Johnson, Mark C; Wissel, Gregory; Erickson, Craig A

    2016-11-01

    In this case series, we describe the acute clinical impact and tolerability of rapid titration of clozapine for treatment of refractory irritability in five hospitalized youth with developmental disability. We offer this descriptive report in an effort to expand the evidence base guiding treatment of refractory aggression in this population. Five youth with developmental disability and severe irritability were admitted to a 10-bed psychiatric crisis stabilization unit where they received thorough psychiatric and medical evaluation. Informed consent was obtained in each case, and each patient underwent rapid titration onto clozapine. Clozapine monitoring guidelines were followed for all patients throughout treatment, and clinical severity at baseline and improvement with treatment was measured by use of the Clinical Global Impressions-Severity scale (CGI-S) and the Clinical Global Impressions-Improvement scale (CGI-I). One female and four males diagnosed with developmental disability and at least one other psychiatric diagnosis, mean age of 13.1 ± 2.1 years, and mean CGI-S at baseline of 5.8, each received clozapine treatment by rapid titration. The mean therapeutic total daily dose of clozapine was 380 ± 200 mg. All patients demonstrated acute clinical improvement with the mean final CGI-I of 2.0, or "much improved." These initial results support the potential utility of clozapine rapid titration for treatment of severe refractory irritability in youth with developmental disability. These patients tolerated clozapine treatment in the short term. Future studies are needed to thoroughly evaluate the long-term safety of clozapine treatment in this population.

  4. Instructional Guide for Vocational Welding. V & TECC Curriculum Guide.

    ERIC Educational Resources Information Center

    Virginia Polytechnic Inst. and State Univ., Blacksburg. Div. of Vocational-Technical Education.

    This trade and industrial curriculum guide for welding is designed for vocational welding programs that provide 960 hours of instruction. The introductory section provides a statement of welding philosophy, objectives, block time schedule, and recommended facilities and equipment. Following the introductory section, ten blocks of instruction are…

  5. Family and Career Management. Teacher's Instructional Guide.

    ERIC Educational Resources Information Center

    Mathieson, Mary

    This instructional guide for a one-half credit course for grades 11-12 emphasizes preparation for family and career roles, effective management, and personal and career effectiveness. Introductory materials are a course description; overview of course design; facilities, equipment, and resources; and how to use the instructional guide. Texas…

  6. Instructional Guide for Vocational Power Mechanics. V & TECC Curriculum Guide.

    ERIC Educational Resources Information Center

    Virginia Polytechnic Inst. and State Univ., Blacksburg. Div. of Vocational-Technical Education.

    This trade and industrial curriculum guide for power mechanics is designed for vocational power mechanics programs that provide 960 hours of instruction. The introductory section provides a statement of philosophy, block time schedule, and the objectives for power mechanics. Following the introductory section, fourteen blocks of instruction are…

  7. Guided Instruction Improves Elementary Student Learning and Self-Efficacy in Science

    ERIC Educational Resources Information Center

    Hushman, Carolyn J.; Marley, Scott C.

    2015-01-01

    The authors investigated whether the amount of instructional guidance affects science learning and self-efficacy. Sixty 9- and 10-year-old children were randomly assigned to one of the following three instructional conditions: (a) guided instruction consisting of examples and student-generated explanations, (b) direct instruction consisting of a…

  8. SOBA: sequence ontology bioinformatics analysis.

    PubMed

    Moore, Barry; Fan, Guozhen; Eilbeck, Karen

    2010-07-01

    The advent of cheaper, faster sequencing technologies has pushed the task of sequence annotation from the exclusive domain of large-scale multi-national sequencing projects to that of research laboratories and small consortia. The bioinformatics burden placed on these laboratories, some with very little programming experience can be daunting. Fortunately, there exist software libraries and pipelines designed with these groups in mind, to ease the transition from an assembled genome to an annotated and accessible genome resource. We have developed the Sequence Ontology Bioinformatics Analysis (SOBA) tool to provide a simple statistical and graphical summary of an annotated genome. We envisage its use during annotation jamborees, genome comparison and for use by developers for rapid feedback during annotation software development and testing. SOBA also provides annotation consistency feedback to ensure correct use of terminology within annotations, and guides users to add new terms to the Sequence Ontology when required. SOBA is available at http://www.sequenceontology.org/cgi-bin/soba.cgi.

  9. Web-Based Instruction: A Guide for Libraries, Third Edition

    ERIC Educational Resources Information Center

    Smith, Susan Sharpless

    2010-01-01

    Expanding on the popular, practical how-to guide for public, academic, school, and special libraries, technology expert Susan Sharpless Smith offers library instructors the confidence to take Web-based instruction into their own hands. Smith has thoroughly updated "Web-Based Instruction: A Guide for Libraries" to include new tools and trends,…

  10. Fostering First Graders' Reasoning Strategies with Basic Sums: The Value of Guided Instruction

    ERIC Educational Resources Information Center

    Purpura, David J.; Baroody, Arthur J.; Eiland, Michael D.; Reid, Erin E.

    2016-01-01

    An intervention experiment served to evaluate the efficacy of highly guided discovery learning of relations underlying add-1 and doubles combination families and to compare the impact of such instruction with minimally guided instruction. After a pretest, 78 first graders were randomly assigned to one of three intervention conditions: highly…

  11. Teacher-Coordinator's Guide for Related Instruction in Multi-Occupation Cooperative Programs.

    ERIC Educational Resources Information Center

    Spooner, Kendrick, Ed.; Mutter, Marylouise, Ed.

    The product of two teacher-coordinator workshops, the guide represents the cooperative efforts of the teacher participants and provides supplementary instructional materials for secondary school multioccupational cooperative programs. The first section of the guide is intended for use in large group classroom instruction and deals with the goals,…

  12. Using Technology with Classroom Instruction that Works. Second Edition

    ERIC Educational Resources Information Center

    Kuhn, Matt; Hubbell, Elizabeth R.; Pitler, Howard

    2012-01-01

    If you've upgraded to the second edition of the landmark book "Classroom Instruction That Works," you need this companion guide to help you use technology to support research-based instruction. The authors follow the revised Instructional Planning Guide that makes it easier for you to know when to emphasize each of the instructional strategies,…

  13. The Impact of Guided Reading Instruction on Elementary Students' Reading Fluency and Accuracy

    ERIC Educational Resources Information Center

    Teets, Agnes Jean

    2017-01-01

    This study examined the impact of Guided Reading instruction on elementary students' ability to read with fluency and accuracy. A one-way analysis of covariance with pre and posttest design was performed and applied to determine the impact of Guided Reading instruction on elementary students' reading fluency and accuracy. The sample of subjects…

  14. When Guided Reading Isn't Working: Strategies for Effective Instruction

    ERIC Educational Resources Information Center

    Wall, Heather

    2014-01-01

    Guided reading is widespread as a small group reading instructional approach, and yet in some cases the original intent of guided reading as a method for encouraging readers' independent strategic thinking has been lost. This article describes one group of teachers' discoveries as they searched for a way to improve their instruction by…

  15. Marketing and Society. Study Guide.

    ERIC Educational Resources Information Center

    Welsh, Robert S.; Blake, Rowland S.

    This self-instructional study guide is part of the materials for a college-level programmed course entitled "Marketing and Society." The study guide is intended for use by students in conjunction with a related textbook, a workbook, a review guide, and a series of instructional tape casettes. The study guide contains a brief introductory section…

  16. Explore Elementary Teachers' Professional Knowledge of Guiding Science Fair Product by Using Different Instruction Model

    ERIC Educational Resources Information Center

    Lu, Chow-Chin

    2013-01-01

    This research is about using two different instruction models, "theory course combined with sample introduction" and "theory course combined with case method teaching", to instruct elementary teachers on how to guide the science fair product in two courses (16 and 12 teachers in each class) and observe their guiding tactics after the instructed…

  17. Comparative Analysis Between Guided Self-Instruction and Conventional Lectures in Neuroanatomy

    ERIC Educational Resources Information Center

    de Carvalho, Claudio A. F.; And Others

    1977-01-01

    A study using 60 first-year medical students in the Santo Amaro Faculty of Medicine, San Paulo, Brazil, found that self-instructional methods such as guided self-instruction or discussion groups are not superior to conventional classes. Self-instruction does have the advantages of low cost and easy applicability. (LBH)

  18. Teacher's Guide to Accompany "Artes Latinae," the Encyclopaedia Britannica Latin Instructional System.

    ERIC Educational Resources Information Center

    Masciantonio, Rudolph; And Others

    This guide, a supplement to the "Artes Latinae Level One Teacher's Manual," prepared for use in the School District of Philadelphia, focuses primarily on how to adapt this course, intended for individualized instruction, to group instruction. Discussion of the multisensory instructional system includes remarks concerning the use of films, study…

  19. Supervision: A Guide to Instructional Leadership-2nd Edition

    ERIC Educational Resources Information Center

    Burke, Peter J.; Krey, Robert D.

    2005-01-01

    The first edition of this book, titled "A Design for Instructional Supervision", provided a structural framework for an effective program of instructional supervision. The basic cognitive thrust of this second edition, "Supervision: A Guide to Instructional Leadership", remains the same as the first. What has changed is the attention to the…

  20. Economic and Societal Factors Instructional Guide. Spanish Student Materials.

    ERIC Educational Resources Information Center

    Hendrix, Mary W.; And Others

    This document is the Spanish language version of the student materials component designed to accompany the Economic and Societal Factors Instructional Guide. Page numbers are consistent with the numbering in that guide. The guide's nine units deal with the following topics: (1) job acquisition (sources of employment, job application, completing…

  1. Economic and Societal Factors Instructional Guide. Student Materials.

    ERIC Educational Resources Information Center

    Hendrix, Mary W.

    These student materials are designed to accompany the Economic and Societal Factors Instructional Guide. Page numbers are consistent with the numbering in that guide. The guide's nine units deal with the following topics: (1) job acquisition (sources of employment, job application, completing the application form, resume, job interview, follow-up…

  2. Teaching Elementary School Students to Be Effective Writers. Summary of Evidence for Instructional Tips Based on the Educator's Practice Guide

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2017

    2017-01-01

    Instructional tips help educators carry out recommendations contained in IES Educator's Practice Guides. This summary of evidence describes the research evidence that supports the use of the instructional tips in classrooms, and is based on a practice guide authored by Steve Graham, Alisha Bollinger, Carol Booth Olson, Catherine D'Aoust, Charles…

  3. AV Instructional Materials Manual; A Sslf-Instructional Guide to AV Laboratory Experiences. Third Edition.

    ERIC Educational Resources Information Center

    Brown, James W., Ed.; Lewis, Richard B., Ed.

    This self-instructional guide to audiovisual laboratory experiences contains 50 exercises designed to give the user active experiences in the practical problems of choosing, using, and inventing instructional materials and in operating and audiovisual equipment. With the exception of the first four exercises (which introduce the user to the manual…

  4. The effects of guided inquiry instruction on student achievement in high school biology

    NASA Astrophysics Data System (ADS)

    Vass, Laszlo

    The purpose of this quantitative, quasi-experimental study was to measure the effect of a student-centered instructional method called guided inquiry on the achievement of students in a unit of study in high school biology. The study used a non-random sample of 109 students, the control group of 55 students enrolled in high school one, received teacher centered instruction while the experimental group of 54 students enrolled at high school two received student-centered, guided inquiry instruction. The pretest-posttest design of the study analyzed scores using an independent t-test, a dependent t-test (p = <.001), an ANCOVA (p = .007), mixed method ANOVA (p = .024) and hierarchical linear regression (p = <.001). The experimental group that received guided inquiry instruction had statistically significantly higher achievement than the control group.

  5. Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation.

    PubMed

    Lord, Caleb C; Ferguson, Daniel; Thomas, Gwynneth; Brown, Amanda L; Schugar, Rebecca C; Burrows, Amy; Gromovsky, Anthony D; Betters, Jenna; Neumann, Chase; Sacks, Jessica; Marshall, Stephanie; Watts, Russell; Schweiger, Martina; Lee, Richard G; Crooke, Rosanne M; Graham, Mark J; Lathia, Justin D; Sakaguchi, Takuya F; Lehner, Richard; Haemmerle, Guenter; Zechner, Rudolf; Brown, J Mark

    2016-07-26

    Adipose triglyceride lipase (ATGL) and comparative gene identification 58 (CGI-58) are critical regulators of triacylglycerol (TAG) turnover. CGI-58 is thought to regulate TAG mobilization by stimulating the enzymatic activity of ATGL. However, it is not known whether this coactivation function of CGI-58 occurs in vivo. Moreover, the phenotype of human CGI-58 mutations suggests ATGL-independent functions. Through direct comparison of mice with single or double deficiency of CGI-58 and ATGL, we show here that CGI-58 knockdown causes hepatic steatosis in both the presence and absence of ATGL. CGI-58 also regulates hepatic diacylglycerol (DAG) and inflammation in an ATGL-independent manner. Interestingly, ATGL deficiency, but not CGI-58 deficiency, results in suppression of the hepatic and adipose de novo lipogenic program. Collectively, these findings show that CGI-58 regulates hepatic neutral lipid storage and inflammation in the genetic absence of ATGL, demonstrating that mechanisms driving TAG lipolysis in hepatocytes differ significantly from those in adipocytes. Copyright © 2016 The Author(s). Published by Elsevier Inc. All rights reserved.

  6. Computer Guided Instructional Design.

    ERIC Educational Resources Information Center

    Merrill, M. David; Wood, Larry E.

    1984-01-01

    Describes preliminary efforts to create the Lesson Design System, a computer-guided instructional design system written in Pascal for Apple microcomputers. Its content outline, strategy, display, and online lesson editors correspond roughly to instructional design phases of content and strategy analysis, display creation, and computer programing…

  7. Reassessing the Potential Activities of Plant CGI-58 Protein

    PubMed Central

    Khatib, Abdallah; Arhab, Yani; Bentebibel, Assia; Abousalham, Abdelkarim; Noiriel, Alexandre

    2016-01-01

    Comparative Gene Identification-58 (CGI-58) is a widespread protein found in animals and plants. This protein has been shown to participate in lipolysis in mice and humans by activating Adipose triglyceride lipase (ATGL), the initial enzyme responsible for the triacylglycerol (TAG) catabolism cascade. Human mutation of CGI-58 is the cause of Chanarin-Dorfman syndrome, an orphan disease characterized by a systemic accumulation of TAG which engenders tissue disorders. The CGI-58 protein has also been shown to participate in neutral lipid metabolism in plants and, in this case, a mutation again provokes TAG accumulation. Although its roles as an ATGL coactivator and in lipid metabolism are quite clear, the catalytic activity of CGI-58 is still in question. The acyltransferase activities of CGI-58 have been speculated about, reported or even dismissed and experimental evidence that CGI-58 expressed in E. coli possesses an unambiguous catalytic activity is still lacking. To address this problem, we developed a new set of plasmids and site-directed mutants to elucidate the in vivo effects of CGI-58 expression on lipid metabolism in E. coli. By analyzing the lipid composition in selected E. coli strains expressing CGI-58 proteins, and by reinvestigating enzymatic tests with adequate controls, we show here that recombinant plant CGI-58 has none of the proposed activities previously described. Recombinant plant and mouse CGI-58 both lack acyltransferase activity towards either lysophosphatidylglycerol or lysophosphatidic acid to form phosphatidylglycerol or phosphatidic acid and recombinant plant CGI-58 does not catalyze TAG or phospholipid hydrolysis. However, expression of recombinant plant CGI-58, but not mouse CGI-58, led to a decrease in phosphatidylglycerol in all strains of E. coli tested, and a mutation of the putative catalytic residues restored a wild-type phenotype. The potential activities of plant CGI-58 are subsequently discussed. PMID:26745266

  8. Managerial Finance. Unit Study Guides.

    ERIC Educational Resources Information Center

    Billingham, Carol J.

    This self-instructional study guide is part of the materials for a college-level programmed course in managerial finance. The study guide is intended for use by students in conjunction with a separate student manual and a series of instructional tape casettes. The study guide contains seven major units that focus in turn on the goal of financial…

  9. The efficacy of video feedback for learning the golf swing.

    PubMed

    Guadagnoli, M; Holcomb, W; Davis, M

    2002-08-01

    This study was designed to examine the efficacy of video instruction relative to that of verbal and self-guided instruction. Before training, 30 golfers were assigned at random to one of three groups: video, verbal or self-guided instruction. Video instruction was defined as a practice session in which the teacher was aided by the use of video. Verbal instruction was defined as practising with the teacher providing verbal feedback. Self-guided practice was defined as practising without the aid of a teacher. The participants had a pre-test, four 90 min practice sessions, an immediate post-test and a 2 week delayed post-test. During the pre-test and post-tests, all participants were required to strike 15 golf balls, with a 7-iron, from an artificial turf mat for distance and accuracy. The results showed that all groups were equal on the pre-test. On the first post-test, the two instruction groups performed worse than the self-guided group. However, on the second post-test, the two instruction groups performed better than the self-guided group, with the video group performing best. We interpret these results to mean that video analysis is an effective means of practice, but that the positive effects may take some time to develop.

  10. North Carolina Articulated Instructional Objectives Guide for Executive Secretary/Business Education (State Pilot Model).

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Community Colleges, Raleigh.

    This articulation instructional objective guide for executive secretary/business education contains summary information on sixteen blocks (courses) of instruction. They are the following: introduction to business, business mathematics, personal development, typing--beginning, records management, business machine--calculating, business…

  11. The 1993-94 Educational Software Preview Guide.

    ERIC Educational Resources Information Center

    Best, Anita, Ed.; Mathis, Judi, Ed.

    This guide lists favorably reviewed, commercially available, microcomputer software for instructional use in preschool through grade 12. The guide is organized by the following curriculum areas: art; business education; computers; health; instructional tools, including authoring systems, computer assisted drafting (CAD), classroom management,…

  12. Clinical outcomes and cost-effectiveness of brief guided parent-delivered cognitive behavioural therapy and solution-focused brief therapy for treatment of childhood anxiety disorders: a randomised controlled trial.

    PubMed

    Creswell, Cathy; Violato, Mara; Fairbanks, Hannah; White, Elizabeth; Parkinson, Monika; Abitabile, Gemma; Leidi, Alessandro; Cooper, Peter J

    2017-07-01

    Half of all lifetime anxiety disorders emerge before age 12 years; however, access to evidence-based psychological therapies for affected children is poor. We aimed to compare the clinical outcomes and cost-effectiveness of two brief psychological treatments for children with anxiety referred to routine child mental health settings. We hypothesised that brief guided parent-delivered cognitive behavioural therapy (CBT) would be associated with better clinical outcomes than solution-focused brief therapy and would be cost-effective. We did this randomised controlled trial at four National Health Service primary child and mental health services in Oxfordshire, UK. Children aged 5-12 years referred for anxiety difficulties were randomly allocated (1:1), via a secure online minimisation tool, to receive brief guided parent-delivered CBT or solution-focused brief therapy, with minimisation for age, sex, anxiety severity, and level of parental anxiety. The allocation sequence was not accessible to the researcher enrolling participants or to study assessors. Research staff who obtained outcome measurements were masked to group allocation and clinical staff who delivered the intervention did not measure outcomes. The primary outcome was recovery, on the basis of Clinical Global Impressions of Improvement (CGI-I). Parents recorded patient-level resource use. Quality-adjusted life-years (QALYs) for use in cost-utility analysis were derived from the Child Health Utility 9D. Assessments were done at baseline (before randomisation), after treatment (primary endpoint), and 6 months after treatment completion. We did analysis by intention to treat. This trial is registered with the ISCRTN registry, number ISRCTN07627865. Between March 23, 2012, and March 31, 2014, we randomly assigned 136 patients to receive brief guided parent-delivered CBT (n=68) or solution-focused brief therapy (n=68). At the primary endpoint assessment (June, 2012, to September, 2014), 40 (59%) children in the brief guided parent-delivered CBT group versus 47 (69%) children in the solution-focused brief therapy group had an improvement of much or very much in CGI-I score, with no significant differences between groups in either clinical (CGI-I: relative risk 1·01, 95% CI 0·86-1·19; p=0·95) or economic (QALY: mean difference 0·006, -0·009 to 0·02; p=0·42) outcome measures. However, brief guided parent-delivered CBT was associated with lower costs (mean difference -£448; 95% CI -934 to 37; p=0·070) and, taking into account sampling uncertainty, was likely to represent a cost-effective use of resources compared with solution-focused brief therapy. No treatment-related or trial-related adverse events were reported in either group. Our findings show no evidence of clinical superiority of brief guided parent-delivered CBT. However, guided parent-delivered CBT is likely to be a cost-effective alternative to solution-focused brief therapy and might be considered as a first-line treatment for children with anxiety problems. National Institute for Health Research. Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. Published by Elsevier Ltd.. All rights reserved.

  13. Seafood Products: An Instructional Guide for Home Economics Programs.

    ERIC Educational Resources Information Center

    Webb, Anita H.; And Others

    The instructional materials contained in this guide are designed for consumer and nutrition education and have been structured in accordance with federal regulations for vocational consumer and homemaking educational programs. Instructional objectives and activities are divided into three levels: level 1 for youth in exploratory/beginning…

  14. Collaborative Common Assessments: Teamwork. Instruction. Results.

    ERIC Educational Resources Information Center

    Erkens, Cassandra

    2015-01-01

    Explore the practical steps teacher teams must take to establish clear, comprehensive assessment systems that guide instruction and strengthen PLCs. This book has the capacity to reignite passion and energy assessment practices bring as tools to guide teaching and learning. Strengthen instructional agility in professional learning communities with…

  15. Planning Guide for Instructional Computing.

    ERIC Educational Resources Information Center

    League for Innovation in the Community Coll., Laguna Hills, CA.

    Designed to assist academic administrators at community colleges in developing strategies for the application of computers to teaching and learning, this guide provides background information and recommendations for the design and implementation of an instructional computing plan. Chapter 1 examines computers as a topic of instruction, as a medium…

  16. Industrial Education. Electricity/Electronics Curriculum Guide, Phase II. Instructional Modules, Level III.

    ERIC Educational Resources Information Center

    Lillo, Robert E.; Soffiotto, Nicholas S.

    Designed for students in the tenth grade, this electricity/electronics curriculum guide contains instructional modules for sixteen units of instruction: (1) orientation, (2) introduction to electricity/electronics, (3) electricity/electronics safety, (4) fundamental skills, (5) direct current circuits, (6) graphical illustrations, (7) circuit…

  17. Evaluator's Guide for Microcomputer-Based Instructional Packages. Revised.

    ERIC Educational Resources Information Center

    International Council for Computers in Education, Eugene, OR.

    Two instruments have been developed to aid teachers and other educators in evaluating educational software and courseware: the "Courseware Description" form and the "Courseware Evaluation" form. Complete instructions for using both forms are provided in this guide, along with the forms themselves. Prior to the instructions is…

  18. Guide to Microcomputer Courseware for Bilingual Education. Revised and Expanded.

    ERIC Educational Resources Information Center

    Sauve, Deborah, Comp.

    The guide to courseware for computer-assisted instruction and computer-managed instruction in bilingual education, English as a second language, and second language instruction contains entries from the National Clearinghouse for Bilingual Education's database and selected courseware for the related areas of special education, vocational…

  19. Air Conditioner Charging. Automotive Mechanics. Air Conditioning. Instructor's Guide [and] Student Guide.

    ERIC Educational Resources Information Center

    Spignesi, B.

    This instructional package, one in a series of individualized instructional units on automobile air conditioning, consists of a student guide and an instructor guide dealing with air conditioning charging. Covered in the module are checking the air conditioning system for leaks, checking and adding refrigerant oil as needed, evacuating the system,…

  20. Principles of Refrigeration. Automotive Mechanics. Air Conditioning. Instructor's Guide [and] Student Guide.

    ERIC Educational Resources Information Center

    Spignesi, B.

    This instructional package, one in a series of individualized instructional units on automobile air conditioning, consists of a student guide and an instructor guide dealing with the principles of refrigeration. Covered in the module are defining the term heat, defining the term British Thermal Unit (BTU), defining the term latent heat, listing…

  1. Pre-Alignment Checks. Automotive Mechanics. Steering & Suspension. Instructor's Guide [and] Student Guide.

    ERIC Educational Resources Information Center

    Spignesi, B.

    This instructional package, one in a series of individualized instructional units on automotive steering and suspension, consists of a student guide and an instructor guide dealing with prealignment checks. Covered in the module are the following steps in a prealignment check: checking the ride height of a vehicle, checking the ball joints and the…

  2. A multimedia guide to spinal cord injury: empowerment through self instruction.

    PubMed

    Van Biervliet, A; Gest, T R

    1995-01-01

    The Spinal Cord Injury (SCI) Project is developing a series of instructional modules on SCI that will be distributed via CD-ROM for patient and family education. The modules are based on an instructional program and patient manual distributed by the Paralyzed Veterans of America. The program includes topics ranging from the anatomy and physiology of spinal cord injuries to legal rights established under the Americans With Disabilities Act. The SCI project expands on the instructional manual by combining digital multimedia techniques with motivational features such as games and personal guides. The user selects a personal guide from among a selection of individuals with spinal cord injuries to guide them through tutorials that include accounts of personal experiences. The guides appear in small video windows at various points throughout the tutorials and give personal insight into the topic at hand. The user can also query the other guides to hear their views on a topic. The user interface incorporates 'seamless access' features, which enable persons with a wide range of disabilities to use the program. Innovative features of these modules are the use of personal instructional guides, motivational games and activities, incorporation of alternative input or access strategies, and the use of high quality, low cost, multimedia production strategies.

  3. Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation

    PubMed Central

    Grond, Susanne; Radner, Franz P.W.; Eichmann, Thomas O.; Kolb, Dagmar; Grabner, Gernot F.; Wolinski, Heimo; Gruber, Robert; Hofer, Peter; Heier, Christoph; Schauer, Silvia; Rülicke, Thomas; Hoefler, Gerald; Schmuth, Matthias; Elias, Peter M.; Lass, Achim; Zechner, Rudolf; Haemmerle, Guenter

    2017-01-01

    Adipose triglyceride lipase (ATGL) and its coactivator comparative gene identification-58 (CGI-58) are limiting in cellular triglyceride catabolism. Although ATGL deficiency is compatible with normal skin development, mice globally lacking CGI-58 die postnatally and exhibit a severe epidermal permeability barrier defect, which may originate from epidermal and/or peripheral changes in lipid and energy metabolism. Here, we show that epidermis-specific disruption of CGI-58 is sufficient to provoke a defect in the formation of a functional corneocyte lipid envelope linked to impaired ω-O-acylceramide synthesis. As a result, epidermis-specific CGI-58-deficient mice show severe skin dysfunction, arguing for a tissue autonomous cause of disease development. Defective skin permeability barrier formation in global CGI-58-deficient mice could be reversed via transgenic restoration of CGI-58 expression in differentiated but not basal keratinocytes suggesting that CGI-58 is essential for lipid metabolism in suprabasal epidermal layers. The compatibility of ATGL deficiency with normal epidermal function indicated that CGI-58 may stimulate an epidermal triglyceride lipase beyond ATGL required for the adequate provision of fatty acids as a substrate for ω-O-acylceramide synthesis. Pharmacological inhibition of ATGL enzyme activity similarly reduced triglyceride-hydrolytic activities in wild-type and CGI-58 overexpressing epidermis implicating that CGI-58 participates in ω-O-acylceramide biogenesis independent of its role as a coactivator of epidermal triglyceride catabolism. PMID:27725204

  4. Resource Guide to Competency-Based Vocational Education: Distributive Education.

    ERIC Educational Resources Information Center

    Foster, Phillip R., Comp.

    This resource guide for classroom teachers contains annotations of resources representing recent instructional development in competency-based education for distributive education. It is also intended to assist curriculum specialists, administrators, and supervisors in development of performance-based instructional programs. The guide is divided…

  5. Resource Guide to Competency-Based Vocational Education: Health Occupations.

    ERIC Educational Resources Information Center

    Foster, Phillip R., Comp.

    This resource guide for classroom teachers contains annotations of resources representing recent instructional development in competency-based education for health occupations. It is also intended to assist curriculum specialists, administrators, and supervisors in development of performance-based instructional programs. The guide is divided into…

  6. An Instructional Guide for Parents.

    ERIC Educational Resources Information Center

    Carambio, Lisa; And Others

    Presented is an instructional guide for parents of severely and profoundly retarded and multiply handicapped children. Developed by 20 graduate students during a summer institute at Duquesne University, the guide suggests activities in communication, self-help and physical development. An introduction provides a definition of the severely involved…

  7. Project Basic Instructional Guide. Instructional Resources. Volume IV. World of Work.

    ERIC Educational Resources Information Center

    Maryland State Dept. of Education, Baltimore.

    Designed to provide a listing of suggested resources to support the Project Basic instructional guide on the world of work, this bibliography consists of annotated listings of student-use materials (library books, films, filmstrips, kits, records, games, audio and videotapes, filmloops, transparencies, periodicals, and pamphlets) arranged…

  8. CNC Turning Technician. A Competency-Based Instructional System.

    ERIC Educational Resources Information Center

    Sloan, Kelly; Hilley, Robert

    This competency-based curriculum guide for instructing students in using computer numerically controlled (CNC) turning machines is one of a series of instructional guides for the machinist field developed in Oklahoma. Although developed jointly with Baxter Technologies Corporation and oriented toward the Baxter Vo-Tec 2000 Future Builder CNC…

  9. Delivering Instruction to Adult Learners. Revised Edition.

    ERIC Educational Resources Information Center

    Cantor, Jeffrey A.

    This one-stop guide for trainers and educators of adults in industry, business, or the professions details a results-oriented instructional strategy that is based on the following principles for instructing adults effectively: (1) act as a leader, helper, guide, change agent, coordinator, and facilitator of learning; (2) promote active…

  10. Intravenous Therapy Instruction for Licensed Practical Nurses. Instructor's Guide.

    ERIC Educational Resources Information Center

    Springer, Pam; Carey, Jean

    This Idaho instructor's guide lists tasks and enabling objectives, outlines instruction, and provides handout masters, overhead masters, and tests for intravenous therapy (IV) instruction for licensed practical nurses. Following an introduction and a list of criteria for successful completion of IV therapy courses, the document lists tasks and…

  11. SU-F-P-50: Performance Evaluation of Optically Stimulated Luminescence (OSL) NanoDots in Therapy and Imaging In-Vivo Dose Measurement During Patient Treatment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kumar, S; Sarkar, B; Kaur, H

    Purpose: This study was designed to evaluate the performance of optically stimulated Luminescence (OSL) nanoDots as in-vivo dosimeter. For the measurements of surface doses as well as scattered plus leakage doses, nanoDots were used during the setup verification as well as during the treatment delivery. Methods: For a total seven patients undergoing radiotherapy by volumetric modulated arc therapy, surface doses from image guidance and scattered plus leakage doses from treatment delivery were measured. Two sets of calibration curves were generated – one for therapy and another for imaging. Two different nanoDots were used for imaging and therapy doses. Imaging nanoDotsmore » were placed at the isocenter only at the time of CBCT and therapy nanoDots were placed at 25 cm away from the isocenter (either in cranial or in caudal direction) only at the time of treatment delivery. During the entire course, nanoDots were placed at the same measurement points. NanoDots were read after 15 minutes of their exposure. For the next fraction, nanoDots were corrected for the residual doses from the previous fractions. Results: Measured surface doses during imaging were 0.14±0.32 cGy, 0.11±0.04 cGy, 0.12±0.53 cGy, 0.04±0.02 cGy, 0.13±0.23 cGy, 0.11±0.43 cGy, 0.10±0.04 cGy with overall mean dose of 0.08±0.1 cGy. Measured doses during treatment delivery, indicative of scattered and leakage dose, were 0.84±0.43 cGy, 1.3±0.4 cGy, 1.4±0.4 cGy, 0.18±0.48 cGy, 0.78±0.29 cGy, 0.27±0.08 cGy, 0.78±0.07 cGy with overall mean dose of 0.61±1.3 cGy. Conclusion: This dosimeter can be used as supplementary unit to verify the doses. No change in the prescription is recommended based on nanoDots measurement. This study is on-going therefore we are presenting only mere number of patients. A large volume data will be presented after completion of the study with proper statistical analysis.« less

  12. Guiding Readers in the Middle Grades

    ERIC Educational Resources Information Center

    Morgan, Denise N.; Williams, Jeffrey L.; Clark, Barbara; Hatteberg, Scott; Hauptman, Gayle Marek; Kozel, Claudia; Paris, Joe

    2013-01-01

    Guided reading is an instructional practice commonly used in primary and intermediate grades (Ford & Opitz, 2008; Fountas & Pinnell, 2001). It is used less in middle grades settings (Allen, 2000) where "one size-fits-all instruction" prevails (Allington, 2012). While teachers can read about the principles of guided reading in…

  13. Vocational Instructional Program Advisory Committee Resource Guide.

    ERIC Educational Resources Information Center

    Rice, Eric; Buescher, Douglas A.

    This guide is intended to provide assistance in developing, organizing, and operating vocational instructional program (VIP) advisory committees. It is designed to be useful for secondary or postsecondary programs that offer training for an occupation or cluster of occupations. The guide is a compilation of suggestions, illustrations, and…

  14. Drafting Fundamentals. Drafting Module 1. Instructor's Guide.

    ERIC Educational Resources Information Center

    Missouri Univ., Columbia. Instructional Materials Lab.

    This Missouri Vocational Instruction Management System instructor's drafting guide has been keyed to the drafting competency profile developed by state industry and education professionals. The guide contains a cross-reference table of instructional materials. Ten units cover drafting fundamentals: (1) introduction to drafting; (2) general safety;…

  15. Factors Considered by Elementary Teachers When Developing and Modifying Mathematical Tasks to Support Children's Mathematical Thinking

    NASA Astrophysics Data System (ADS)

    Fredenberg, Michael Duane

    The idea that problems and tasks play a pivotal role in a mathematics lesson has a long standing in mathematics education research. Recent calls for teaching reform appeal for training teachers to better understand how students learn mathematics and to employ students' mathematical thinking as the basis for pedagogy (CCSSM, 2010; NCTM, 2000; NRC 1999). The teaching practices of (a) developing a task for a mathematics lesson and, (b) modifying the task for students while enacting the lesson fit within the scope of supporting students' mathematical thinking. Surprisingly, an extensive search of the literature did not yield any research aimed to identify and refine the constituent parts of the aforementioned teaching practices in the manner called for by Grossman and xiii colleagues (2009). Consequently, my research addresses the two questions: (a) what factors do exemplary elementary teachers consider when developing a task for a mathematics lesson? (b) what factors do they consider when they modify a task for a student when enacting a lesson? I conducted a multiple case study involving three elementary teachers, each with extensive training in the area of Cognitively Guided Instruction (CGI), as well as several years experience teaching mathematics following the principles of CGI (Carpenter et al., 1999). I recorded video of three mathematics lessons with each participant and after each lesson I conducted a semi-structured stimulated recall interview. A subsequent follow-up clinical interview was conducted soon thereafter to further explore the teacher's thoughts (Ginsberg, 1997). In addition, my methodology included interjecting myself at select times during a lesson to ask the teacher to explain her reasoning. Qualitative analysis led to a framework that identified four categories of influencing factors and seven categories of supporting objectives for the development of a task. Subsets of these factors and objectives emerged as particularly relevant when the teachers decided to modify a task. Moreover, relationships between and among the various factors were identified. The emergent framework from this study offers insight into decompositions of the two teaching practices of interest, and, in particular, the utility of the number choices made by the teachers.

  16. The California State Environmental Education Guide. A Curriculum Guide for Kindergarten through Sixth Grade.

    ERIC Educational Resources Information Center

    Sly, Carolie; And Others

    The purpose of this guide is to provide teachers and other educators with classroom lessons and instructional techniques that build a fundamental understanding of the environment. The guide is aimed at grades kindergarten through sixth and consists of eight instructional units and six action projects. Each unit is organized around a theme and the…

  17. The Potential of CGI: Using Pre-Built CGI Scripts to Make Interactive Web Pages.

    ERIC Educational Resources Information Center

    Nackerud, Shane A.

    1998-01-01

    Describes CGI (Common Gateway Interface) scripts that are available on the Web and explains how librarians can use them to make Web pages more interactive. Topics include CGI security; Perl scripts; UNIX; and HTML. (LRW)

  18. Methylation variable position profiles of hMLH1 promoter CpG islands in human sporadic colorectal carcinoma.

    PubMed

    Huang, Qing; Huang, Jun-Fu; Zhang, Bo; Baum, Larry; Fu, Wei-Ling

    2012-03-01

    Aberrant hypermethylation of CpG islands (CGIs) in hMLH1 promoter regions has been well known to play an important role in the tumorigenesis of human sporadic colorectal carcinoma (SCRC). In this study, bisulfite sequencing was performed to analyze the methylation variable positions (MVPs) profiles of hMLH1 promoter CGIs in 30 clinical SCRC patients, and further analysis was carried out to evaluate the associations between the CGI methylation and the clinicopathological features in SCRC. Among the 2 CGIs in the hMLH1 promoter, that is, CGI-I and CGI-II, 20% (6/30) and 13% (4/30) of the patients had methylated CGI-I and CGI-II, respectively. Suppressed expression of hMLH1was significantly correlated with methylation of CGI-I but not CGI-II. Further analysis of the MVP profiles of CGI-I showed that most of the MVPs were hypermethylated and others were poorly methylated or unmethylated. The profiles could be classified into at least 4 groups based on the methylation status of 3 MVPs at positions 21 to 23 in CGI-I. All 6 patients with methylated CGI-I belonged to group I. This result suggests that the above 3 MVPs in CGI-I should be a targeted region to further analyze the epigenetic features of hMLH1 in human SCRC. Our results further suggest that MVP profiling is useful for identifying the aberrantly methylated CGIs associated with suppressed gene expression.

  19. Computer Assisted Drafting (CNC) Drawings. Drafting Module 6. Instructor's Guide.

    ERIC Educational Resources Information Center

    Missouri Univ., Columbia. Instructional Materials Lab.

    This Missouri Vocational Instruction Management System instructor's drafting guide has been keyed to the drafting competency profile developed by state industry and education professionals. This unit contains information on computer-assisted drafting drawings. The guide contains a cross-reference table of instructional materials and 20 worksheets.…

  20. Instructional Guide for Autobody Repair.

    ERIC Educational Resources Information Center

    Virginia Polytechnic Inst. and State Univ., Blacksburg. Dept. of Education.

    The curriculum guide was developed to serve as a statewide model for Virginia auto body repair programs. The guide is designed to 1,080 hours of instruction in eleven blocks: orientation, introduction, welding and cutting, techniques of shaping metal, body filler and fiberglass repairs, body and frame, removing and replacing damaged parts, basic…

  1. Guided Reading in Inclusive Middle Years Classrooms

    ERIC Educational Resources Information Center

    Lyons, Wanda; Thompson, Scott Anthony

    2012-01-01

    Teachers in inclusive classrooms are challenged to provide reading instruction for students with a wide range of instructional levels. This article reports on the implementation of guided reading in four middle years inclusive classrooms, the impact on student engagement and reading progress, and teacher perspectives on the guided reading…

  2. Career Opportunities Instructional Guide. Spanish Student Materials.

    ERIC Educational Resources Information Center

    Hendrix, Mary W.; And Others

    This document is the Spanish language version of the student materials component designed to accompany the Career Opportunities Instructional Guide. Page numbers are consistent with numbering in that guide. Seventeen units are provided. The materials in Unit 1 concern various aspects of locating information about occupations; Unit 2 provides an…

  3. Career Opportunities Instructional Guide. Student Materials.

    ERIC Educational Resources Information Center

    Hendrix, Mary W.

    These student materials are designed to accompany the Career Opportunities Instructional Guide. Page numbers are consistent with the numbering in that guide. Seventeen units are provided. The materials in Unit 1 concern aspects of locating information about occupations; Unit 2 provides an introduction to the 15 occupational clusters. Each of the…

  4. The Effect of Guided Reading Instruction on Reading Achievement

    ERIC Educational Resources Information Center

    Underwood, Vanda Lea

    2010-01-01

    Although reading achievement correlates highly with a student's ability to do well in school, not all children achieve in reading. The purpose of this mixed-method study was to investigate whether reading instruction provided in small groups at the child's own reading level, known as "guided reading instruction," would result in…

  5. Key Reading Recovery Strategies to Support Classroom Guided Reading Instruction

    ERIC Educational Resources Information Center

    Lipp, Jamie R.; Helfrich, Sara R.

    2016-01-01

    Effective teachers are continuously striving to improve their instruction. Reading Recovery teachers have detailed and specific literacy training and expertise that can be of great value to classroom teachers, especially in the area of guided reading instruction. This article explores the ways in which key Reading Recovery strategies can be…

  6. Staff Manual for Instructional Material Centers. Fourth Revised Edition.

    ERIC Educational Resources Information Center

    Petrucci, Martha

    For media center volunteers or inexperienced technicians, a workshop training guide provides reference and assistance in everyday problems and situations that arise in an instructional material center (IMC). Two five-hour days of instruction and participation, using the guide, are suggested for workshops. Step-by-step processing of book materials,…

  7. The Cutting Edge: Workplace English. Instructional Guide.

    ERIC Educational Resources Information Center

    El Paso Community Coll., TX. Literacy Center.

    The instructional guide for the Cutting Edge workplace literacy program, a cooperative project of El Paso Community College (Texas) and Levi Strauss and Company, is an expanded version of one appendix the project handbook. It describes and provides an instructional model for the three-part, job-specific, video-based program of English as a Second…

  8. Entelek Programmed Instruction Guide. Volume l: Elementary/High School. 3rd Edition.

    ERIC Educational Resources Information Center

    Entelek, Inc., Newburyport, MA.

    Individualized instruction has become an important objective in schools. This programmed instruction guide provides information about the ENTELEK system for elementary and high schools. The data bank covers a variety of subject areas and is catalogued according to the Dewey Decimal System: library; psychology; logic; political science; economics;…

  9. Health Education Guide: A Design for Teaching K-12.

    ERIC Educational Resources Information Center

    Barrett, Morris

    This teaching guide to health education includes instruction units for grades K-12. Section 1 discusses the need for health education and includes a scope and sequence chart for each of the instruction units. Section 2 consists of instruction units in the areas of physical development, social and emotional development, chemicals and addiction, and…

  10. Graphic Arts: Process Camera, Stripping, and Platemaking. Teacher Guide.

    ERIC Educational Resources Information Center

    Feasley, Sue C., Ed.

    This curriculum guide is the second in a three-volume series of instructional materials for competency-based graphic arts instruction. Each publication is designed to include the technical content and tasks necessary for a student to be employed in an entry-level graphic arts occupation. Introductory materials include an instructional/task…

  11. Industrial Education. Electricity/Electronics Curriculum Guide, Phase II. Instructional Modules, Level II.

    ERIC Educational Resources Information Center

    Lillo, Robert E.; Soffiotto, Nicholas S.

    Designed for students in the ninth grade, this electricity/electronics curriculum guide contains instructional modules for twenty-four units of instruction. Among the modules included are (1) introduction to the world of electricity, (2) electrical safety, (3) the electrical team, (4) resistance and resistors, (5) electric lamps and heating…

  12. Graphic Arts: Orientation, Composition, and Paste-Up. Teacher Guide.

    ERIC Educational Resources Information Center

    Feasley, Sue C., Ed.

    This curriculum guide is the first in a three-volume series of instructional materials for competency-based graphic arts instruction. Each publication is designed to include the technical content and tasks necessary for a student to be employed in an entry-level graphic arts occupation. Introductory materials include an instructional/task analysis…

  13. Industrial Education. Electricity/Electronics Curriculum Guide, Phase II. Instructional Modules, Level I (9 Week).

    ERIC Educational Resources Information Center

    Lillo, Robert E.; Soffiotto, Nicholas S.

    Designed for students in grades 7 and 8, this electricity/electronics curriculum guide contains instructional modules for ten units of instruction (nine-week class): (1) orientation; (2) understanding electricity; (3) safety; (4) methods to generate electricity; (5) wiring tools and wire; (6) soldering; (7) magnetism and electromagnetism; (8)…

  14. Industrial Education. Electricity/Electronics Curriculum Guide, Phase II. Instructional Modules, Level I (18 Week).

    ERIC Educational Resources Information Center

    Lillo, Robert E.; Soffiotto, Nicholas S.

    Designed for students in grades 7 and 8, this electricity/electronics curriculum guide contains instructional modules for twelve units of instruction: (1) orientation; (2) understanding electricity; (3) safety; (4) methods to generate electricity; (5) wiring tools and wire; (6) soldering; (7) magnetism and electromagnetism; (8) circuits, symbols,…

  15. Instructional Materials on Africa for Primary Grades. An Instructional Unit for Grade One.

    ERIC Educational Resources Information Center

    Smith, Allie Evelyn

    Focusing on traditional African families, villages, and cultures, this teaching guide presents objectives, activities, resources, and evaluation suggestions for use in grade one social studies African area programs. The instructional guide is a product of a summer workshop for teachers on African curriculum development. It is intended as the basis…

  16. The corpus-predominant gastritis index can be an early and reversible marker to identify the gastric cancer risk of Helicobacter pylori-infected nonulcer dyspepsia.

    PubMed

    Cheng, Hsiu-Chi; Tsai, Yu-Ching; Yang, Hsiao-Bai; Yeh, Yi-Chun; Chang, Wei-Lun; Kuo, Hsin-Yu; Lu, Cheng-Chan; Sheu, Bor-Shyang

    2017-08-01

    Corpus-predominant gastritis index (CGI) is an early histological marker to identify Helicobacter pylori-infected gastric cancer relatives at risk of cancer. This study validated whether CGI is more prevalent in H. pylori-infected nonulcer dyspepsia (NUD) subjects than in duodenal ulcer (DU) controls and whether it is reversible after H. pylori eradication or is correlated with noninvasive biomarkers. In this longitudinal cohort study, 573 H. pylori-infected subjects were enrolled, including 349 NUD and 224 DU. Gastric specimens were provided to assess CGI, spasmolyic polypeptide-expressing metaplasia (SPEM), and Operative Link on Gastric Intestinal Metaplasia assessment (OLGIM). Serum pepsinogen I and II levels were assessed using enzyme-linked immunosorbent assay. CGI subjected were followed up at least 1 year after H. pylori eradication. NUD subjects had higher prevalence rates of CGI (47.0% vs 29.9%, P<.001) and OLGIM stages III-IV (24.1% vs 15.2%, P=.01) than controls. CGI was highly prevalent in NUD subjects after the age of 40, which was 10 years earlier than atrophic gastritis and intestinal metaplasia. NUD subjects with CGI had higher risk of SPEM (OR 2.86, P<.001) and lower serum pepsinogen I/II ratios (P<.001) than those without CGI. Serum pepsinogen I/II ratios <9 could predict CGI modestly (AUROC 0.69, 95% CI: 0.63-0.74). CGI was regressed after eradication (P<.001). CGI was more prevalent in H. pylori-infected NUD subjects than in controls, was correlated with SPEM, and may serve as a marker earlier than OLGIM to indicate risk of gastric cancer. Moreover, CGI could be regressed after eradication. © 2017 John Wiley & Sons Ltd.

  17. An alternative approach to account for patient organ doses from imaging guidance procedures.

    PubMed

    Nelson, Alan P; Ding, George X

    2014-07-01

    To investigate the feasibility of an alternative method of accounting for additional organ doses resulting from image guidance procedures during patient treatment planning through tabulated values based on scan protocol and scan site. Patient-specific imaging dose to 30 patients resulting from Varian OBI kV-CBCT scans using the Standard Head (17 patients), Low-dose Thorax (8 patients), and Pelvic (5 patients) scan protocols were retrospectively calculated using Monte Carlo methods. Dose dependence on scan location and patient geometry was explored. Patient organ doses were analyzed by using dose-volume histograms and expressed by the mean, minimum dose delivered to 50% of the organ volume, D50. The reported doses are dose-to-medium instead of dose-to-water. The organ doses from all patient-specific calculations show predictable and limited ranges across patients. For brain isocenters using Standard Head Scans: Bone: 0.7-1.1 cGy, Brain: 0.2-0.3 cGy, Brainstem: 0.2-0.3 cGy, Skin: 0.3-0.4 cGy, Eye: 0.03-0.3 cGy. For head and neck patients using the Standard Head Scan: Bone: 0.3-0.6 cGy, Parotids: 0.3-0.4 cGy, Spinal Cord: 0.15-0.25 cGy, Thyroid: 0.1-0.25 cGy, Skin: 0.2-0.3 cGy, Trachea-Esophagus: 0.1-0.2 cGy. For chest using Thorax Scans: Bone: 1.1-1.8 cGy, Soft tissue organs (Bowel, Lung, Heart, Kidney, Esophagus, and Spinal Cord): 0.3-0.6 cGy. For abdominal site using Pelvic Scans: Bone: 3.2-4.2 cGy. Soft tissue organs (Bladder, Bowel, Rectum, Prostate, and Skin) D50s fell between 1.2 and 2.2 cGy. Femoral Heads: 2.5-3.4 cGy. It is adequate to estimate and account for organ dose by using tabulated values based on scan procedure and site because organ doses from imaging procedures are only modestly dependent upon scan location and body size. Considering the dose variation and magnitude of dose from each scan protocol in comparison to therapeutic doses, this approach provides a simple alternative to account for additional imaging guidance doses during patient treatment planning. Clinicians can use these tabulated values to make informed decisions in selecting the appropriate imaging procedures and imaging frequency during radiotherapy treatment. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  18. SU-E-T-583: Operated Left Breast and Chest Wall Radiotherapy: A Dosimetric Comparison Between 3DCRT, IMRT and VMAT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sarkar, B; Roy, S; Munshi, A

    2015-06-15

    Purpose: To evaluate the comparative dosimetric efficacy between field and field 3DCRT(FnF), multiple field Intensity modulated radiotherapy (SnS IMRT) and, partial arc volumetric modulated arc therapy (VMAT) in case of post operative left side breast and chest wall irradiation. Methods: CT study set of fifteen post-operative left breast and chest wall patient was tested for a treatment plan of 50Gy in 25 fraction using partial arc VMAT, SnSIMRT and tangential beam 3DCRT . 3DCRT FnF gantry angle was ranging for left medial tangential 290±17{sup 0} and Lt lateral tangential l14°±12{sup 0}. For IMRT four fixed beam at gantry angle G130{supmore » 0} G110{sup 0} G300{sup 0} and G330{sup 0} was used, in case of insufficient dose another beam G150{sup 0} was added. In case of partial arc VMAT, lateral tangential arc G130{sup 0}-G100{sup 0} and medial tangential arc G280{sup 0}-G310{sup 0}. Inverse optimization was opted to cover at least 95%PTV by 95% prescription dose (RxD) and a strong weightage on reduction of heart and lung dose. PTV coverage was evaluated for it’s clinically acceptability depending on the tumor spatial location and its quadrant. Out of the three plans, any one was used for the actual patient treatment. Results: Dosimetric analysis done for breast PTV, left lung, heart and the opposite breast. PTV mean dose and maximum dose was 5129.8±214.8cGy, 4749.0±329.7cGy, 5024.6±73.4cGy and 5855.2±510.7cGy, 5340.7±146.1cGy, 5347.2±196.8cGy for FnF, VMAT and IMRT respectively. Ipsilateral lung volume receiving 20Gy and 5Gy was 23.6±9.5cGy and 32.7±10.3cGy for FnF, 18.6±8.7cGy and 38.8±15.2cGy for VMAT and 25.7±9.6cGy and 50.7±8.4cGy for IMRT respectively. Heart mean and 2cc dose was 867.9±456.7cGy and 5038.5±184.3cGy for FnF, 532.6±263cGy and 3632.1±990.6 for VMAT, 711±229.9cGy and 4421±463.7cGy for IMRT respectively. VMAT shows minimum contralateral breast dose 168±113.8cGy. Conclusion: VMAT shows a better tumor conformity, minimum heart, ipsilateral lung and opposite breast dose. Cardiac Toxicity and risk of contralateral breast cancer can be reduce using VMAT.« less

  19. A Bachelor of Engineering Technology Curriculum in Water Quality Management: Course Guides.

    ERIC Educational Resources Information Center

    Cole, Charles A.; And Others

    Contained are course guides for a Bachelor of Engineering Technology (BET) Curriculum in Water Quality Management. Detailed course content, as well as instructional resources, are included in this volume. Each guide is written in behavioral terms using the instructional objective format. A suggested curriculum is shown with methods of…

  20. Articulated Instruction Objectives Guide for Drafting. Final Document for Articulation of Drafting.

    ERIC Educational Resources Information Center

    Henderson, Wm. Edward, Jr.

    Intended for use in competency-based and criterion-referenced vocational programs, this articulated, performance-based instruction objectives guide for Drafting I is designed for reference use in the articulation of drafting programs at the secondary and postsecondary levels. It consists of a description of the development of the guide, 14…

  1. Missouri Introduction to Materials and Processing Technology. Instructor Guide.

    ERIC Educational Resources Information Center

    Missouri Univ., Columbia. Instructional Materials Lab.

    This guide is intended to support a high school specialization course in materials and processing technology. The document contains three sections: (1) information on using the material; (2) a set of instructor guides for eight instructional units; (3) 15 technological activity modules and teacher and student instructions for their use; and (4)…

  2. The Byrne Guide for Inclusionary Cultural Content.

    PubMed

    Byrne, Michelle M; Weddle, Carriette; Davis, Ernestine; McGinnis, Patricia

    2003-06-01

    This article describes the background for development of The Byrne Guide for Inclusionary Cultural Content, which may help nurse educators evaluate and create instructional materials that include diverse groups. Curricular implications of diversity, as well as six categories of instructional bias are included in the background of information that contributed to the development of this Guide.

  3. French: Foreign Language Curriculum Guide, Grades 7-12.

    ERIC Educational Resources Information Center

    Farmington Public Schools, CT.

    This curriculum guide, developed for an ungraded language program at the secondary school level, allows for a steady progression of skills from unit to unit. Based on the audiolingual approach to language instruction, the guide is divided into four sections: (1) concepts to be taught, (2) references to instructional materials, (3) special…

  4. INSTRUCTIONAL GUIDE FOR ELECTRICITY, JUNIOR HIGH SCHOOL INDUSTRIAL ARTS.

    ERIC Educational Resources Information Center

    GOLDSMITH, J. LYMAN

    THIS GUIDE IS DESIGNED TO PROVIDE A PRACTICAL REFERENCE FOR TEACHERS PLANNING INSTRUCTION CONCERNING ELECTRICITY IN JUNIOR HIGH SCHOOL INDUSTRIAL ARTS CLASSES. THE GUIDE IS FOR A 10-WEEK COURSE DESIGNED TO PROVIDE THE STUDENT WITH EXPLORATORY EXPERIENCES INVOLVING THE BASIC PRINCIPLES AND APPLICATIONS OF ELECTRICITY AND ELECTRONICS. THE PROPER USE…

  5. Guide to Using the Teacher Data Use Survey. REL 2017-166

    ERIC Educational Resources Information Center

    Wayman, Jeffrey C.; Wilkerson, Stephanie B.; Cho, Vincent; Mandinach, Ellen B.; Supovitz, Jonathan A.

    2016-01-01

    The Teacher Data Use Survey can be used to query teachers, administrators, and instructional support staff about how teachers use data to support instruction, their attitudes toward data, and the supports that help teachers use data. This guide provides step-by-step instructions to help district and school planners implement the survey. The…

  6. The Laboratory. Guides for the Improvement of Instruction in Higher Education, No. 9.

    ERIC Educational Resources Information Center

    Alexander, Lawrence T.; And Others

    This guide for the improvement of instruction in higher education is designed to aid the educator in planning and conducting laboratory instruction. The examples used refer primarily to science laboratories. Topics discussed include: deciding whether or not to use the laboratory method (with a discussion of discovery learning or the processes of…

  7. An Alternative Time for Telling: When Conceptual Instruction Prior to Exploration Improves Mathematical Knowledge

    ERIC Educational Resources Information Center

    Fyfe, Emily R.; DeCaro, Marci S.; Rittle-Johnson, Bethany

    2013-01-01

    An emerging consensus suggests that guided discovery, which combines discovery and instruction, is a more effective educational approach than either one in isolation. The goal of this study was to examine two specific forms of guided discovery, testing whether conceptual instruction should precede or follow exploratory problem solving. In both…

  8. A Guide to Computer Simulations of Three Adaptive Instructional Models for the Advanced Instructional System Phases II and III. Final Report.

    ERIC Educational Resources Information Center

    Hansen, Duncan N.; And Others

    Computer simulations of three individualized adaptive instructional models (AIM) were undertaken to determine if these models function as prescribed in Air Force technical training programs. In addition, the project sought to develop a user's guide for effective understanding of adaptive models during field implementation. Successful simulations…

  9. Physical Education Opportunity Program for Exceptional Learners (PEOPEL): A Teacher's Guide for Secondary Schools. Second Edition.

    ERIC Educational Resources Information Center

    Irmer, Larry D.; And Others

    The instructional guide for PEOPEL (Physical Education Opportunity Program for Exceptional Learners) contains 36 units of instruction for use with handicapped junior and senior high school students. The units contain basic performance objectives which have been task analyzed in an effort to individualize instruction. Each unit is divided into four…

  10. State Articulated Instructional Objectives Guide for Occupational Education Programs. State Pilot Model for Automotive Mechanics (DCC V-003) and Automotive Mechanics (High School).

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Community Colleges, Raleigh.

    This articulation instructional objective guide for automotive mechanics contains summary information on fifteen blocks (courses) of instruction. They are introduction to automotive technology; lubrication and vehicle operating maintenance; cooling system maintenance and repair; automobile heater maintenance and repair; braking system maintenance…

  11. Scientific Outreach for K-6 Students: The LTER Schoolyard Children's Book Series

    NASA Astrophysics Data System (ADS)

    Williams, M.; McKnight, D.

    2009-04-01

    Here we present information on the many steps involved in writing and publishing a science book for children. This talk builds on the success of the children's' book: My Water Comes from the Mountains, written by Tiffany Fourment and illustrated by Dorothy Emerling, and sponsored by the NWT LTER outreach program. The narrative of the book takes children of ages 7-10 on an illustrative journey from glacial and snowpack sources high on the Continental Divide to the plains and water in their faucet tap, introducing them to the distinctive wildlife and ecosystems along the way, including the diverse uses and human impact of water in Boulder Creek and St. Vrain watersheds. We then talk about developing and distributing a teachers guide and materials packet developed for instructional use in the classroom and based on the children's book: MY H2O: My Water Comes from the Mountains Teacher's Curriculum Guide and Kit; edited by Colleen Flanagan, organizational authors Colleen Flanagan, Kenneth Nova, and Tiffany Fourment. The Teacher's Guide adds accompanying lessons, incorporation of water-wise sustainability in the classroom and community, and improvement of environmental education teaching skills with exemplary projects and practical edification. Direct feedback from the teachers was incorporated into the Guide, and their questions about the water cycle in the Front Range were addressed thoroughly. Utilizing local expertise and resources, the Guide encompassed four themes: 1) Water cycle, 2) Watershed, 3) Flora/Fauna/Life Zones, and 4) Human Interaction/Impact with Water. Each section includes a thorough explanation of 7-8 interactive projects, along with corresponding background information, suggested approaches and the book's parallel page number(s) for supplementary purposes. We end by showing how this model was used to develop the children's book "The Lost Seal (http://www.mcmlter.org/lostseal/) as the next stage in a national program. The Lost Seal children's story, written by Antarctic scientist Diane McKnight, describes the first documented encounter with a live seal in the remote McMurdo Dry Valleys of Antarctica. Additional website information on the children's book "My Water Comes from the Mountains" is available at http://intranet.lternet.edu/archives/documents/Newsletters/NetworkNews/fall04/fall04_pg15.htm. All 433 pieces of orginal artwork for My Water Comes from the Mountains can be viewed at http://culter.colorado.edu/exec/Mywater/mywater_search_page.cgi.

  12. Teachers' Guide For Aviation Education.

    ERIC Educational Resources Information Center

    Aviation/Space, 1979

    1979-01-01

    This teacher's guide outlines the objectives, instructional procedures, student activities, and expected outcomes of an instructional unit on careers in aviation, designed for fifth and sixth grade students. It emphasizes aerospace activities and job opportunities in aviation. (GA)

  13. The impact of library instruction: do first-year medical students use library resources specifically highlighted during instructional sessions?*

    PubMed Central

    Rafferty, Ryan S.

    2013-01-01

    Objectives: The research sought to determine if first-year medical students consulted and cited resources specifically highlighted during library instructional sessions. Methods: Students attended a library resources instructional session. Resources that pertained to the students' assignment were demonstrated and discussed. The students created a report including citations from relevant literature. The citations were analyzed and categorized as: a resource discussed at the instructional session, a resource found on the course LibGuide, a library resource, course material, or some other resource. All citations were subcategorized as print or electronic. Results: Three years (2008–2011) of data analyzing 2,983 citations showed that 49.55% of all citations were from resources discussed during library instructional sessions; 21.86% came from resources with links on the course LibGuide; 77.51% were from library resources; and 90.68% came from electronic resources. Conclusion: Students cited resources specifically highlighted during library instructional sessions for their assignments. The percentage of all citations coming from resources highlighted during the instructional sessions or found on the course LibGuide indicates that library instruction had an impact on the students' work. PMID:23930092

  14. SU-E-T-619: Comparison of CyberKnife Versus HDR (SAVI) for Partial Breast Irradiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mooij, R; Ding, X; Nagda, S

    2014-06-15

    Purpose: Compare SAVI plans and CyberKnife (CK) plans for the same accelerated course. Methods and Materials: Three SAVI patients were selected. Pre-SAVI CTs were used for CK planning. All prescriptions are 3400cGy in 10 fractions BID. Max dose to skin and chestwall is 425cGy. For SAVI, PTV is a 1cm expansion of the cavity minus the cavity. For CK, CTV is a 1cm expansion of the seroma, with 2mm margin. CK plans are normalized to SAVI, so that in both cases the 323cGy isodose line covers the same percentage of PTV. For CK Fiducial/Synchrony tracking is used. Results: In themore » following, all doses are per fraction and results are averaged. The PTVs for the CK plans are 2.4 times larger than the corresponding SAVI PTVs. Nonetheless the CK plans meet all constraints and are superior to SAVI plans in several respects. Max skin dose for SAVI vs CK is 332cGy vs 337cGy. Max dose to chestwall is 252cGy vs 286cGy. The volume of lung over 125cGy is 6.4cc for SAVI and 2.5cc for CK. Max heart dose is 60cGy for SAVI and 83cGy for CK. The volume of PTV receiving over 425cGy is 49cc for SAVI and 1.3cc for CK. Max dose to contra-lateral breast is 16cGy for SAVI and 4.5cGy for CK. Conclusion: CK PTVs are directly derived from the seroma. Corresponding SAVI PTVs tend to be much smaller. Dosimetrically, CK plans are equivalent or superior to SAVI plans despite the larger PTVs. Interestingly, the dose delivered to the lung is higher in SAVI vs CK. Fiducial/Synchrony tracking employed by CK might reduce errors in delivery compared to errors associated with shifts of the SAVI implant. In conclusion, when CK is an option for partial breast irradiation it may preferable to SAVI.« less

  15. Chemical Equilibrium, Unit 2: Le Chatelier's Principle. A Computer-Enriched Module for Introductory Chemistry. Student's Guide and Teacher's Guide.

    ERIC Educational Resources Information Center

    Jameson, A. Keith

    Presented are the teacher's guide and student materials for one of a series of self-instructional, computer-based learning modules for an introductory, undergraduate chemistry course. The student manual for this unit on Le Chatelier's principle includes objectives, prerequisites, pretest, instructions for executing the computer program, and…

  16. Jobs and Engines, Teacher's Guide: Political Issues. Comparing Political Experiences, Experimental Edition.

    ERIC Educational Resources Information Center

    Gillespie, Judith A.; Lazarus, Stuart

    This teacher's guide to unit 5 of the 12th-grade second-semester "Comparing Political Experiences" course provides specific objectives and instructional procedures for each of the five activities that focus on the case study of the Cummins Engine Company. In addition, the guide provides instructions for coordinating the use of the…

  17. E-Readers and the Effects on Students' Reading Motivation, Attitude and Comprehension during Guided Reading

    ERIC Educational Resources Information Center

    Long, Deanna; Szabo, Susan

    2016-01-01

    This quasi-experimental mixed methods study examined the use of e-readers during guided reading instruction and its impact on 5th grade students' reading motivation, attitude toward reading, and reading comprehension. For 10 weeks, 19 students received guided reading instruction by means of the traditional paper/text format, while 16 students…

  18. Health Occupations Education: Suggested Curriculum Guide for Nursing Assistant. Curriculum Guide-3.

    ERIC Educational Resources Information Center

    Virginia Polytechnic Inst. and State Univ., Blacksburg. Div. of Vocational-Technical Education.

    The curriculum guide, developed to serve as a statewide model for nursing assistant programs, offers teaching suggestions for nursing assistant courses in the public schools. It is designed for 270 hours of theory and 200 hours of clinical instruction. There are 11 units of instruction: orientation; human behavior; medical communication skills;…

  19. Germany: The Search for Unity. Guide for Workshop Leaders.

    ERIC Educational Resources Information Center

    Blankenship, Glen

    This document is designed to support teachers in the use of instructional materials related to contemporary Germany. The materials in this guide provide the basis for a one-day, 5 hour inservice session. The workshop agenda begins the guide and sets out the schedule of times for different activities and instruction. The suggested format can be…

  20. Your Credit Rights: An Instructional Unit on Consumer Credit Protection. Revised.

    ERIC Educational Resources Information Center

    Jensen, Barbara J.; And Others

    This instructional guide adds two new sections to the original guide published in May 1982. The guide was designed to assist educators in teaching the topics of consumer credit and consumer credit protection to secondary and postsecondary students in various economics and business courses, as well as in adult and community education courses. The…

  1. SCDC Spanish Curricula Units. Social Science Strand, Unit 2, Grade One, Teacher's Guide--Multi-Ethnic Edition.

    ERIC Educational Resources Information Center

    Spanish Curricula Development Center, Miami Beach, FL.

    Building on a unit designed to help first graders adjust to the classroom environment, this teacher's guide for the second bilingual social science instructional unit includes material which expands the conceptual field of the child to the family. The Spanish-English guide presents instructional and assessment activities for kits five through…

  2. Teaching Elementary School Students to Be Effective Writers: Instructional Tips Based on the Educator's Practice Guide

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2017

    2017-01-01

    Instructional tips help educators carry out recommendations contained in IES Educator's Practice Guides. The tips, based on a practice guide authored by Steve Graham, Alisha Bollinger, Carol Booth Olson, Catherine D'Aoust, Charles MacArthur, Deborah McCutchen, and Natalie Olinghouse, translate these recommendations into actionable approaches that…

  3. Import Auto Technician; Curriculum Guide for the Development of an Import Automobile Technology Program.

    ERIC Educational Resources Information Center

    East Los Angeles Coll., CA.

    In this curriculum guide, courses in a three-phase community college program for training import automobile technicians are provided. Following an introducation to the guide, the background of the development of the program, the program, the instruction, support for instruction, and the import automobile industry are discussed. Sample options for…

  4. The Teaching of Sight Words: Ways and Means. Instructional Concept Guide No. 7.

    ERIC Educational Resources Information Center

    Strader, Susan; And Others

    The instructional concept guide is part of a system developed for tutor training and support. It is primarily designed for volunteers, but it can also be adapted to the training of paraprofessional tutors for any type of adult literacy program. A key component in the system is the Tutor Support Library, consisting of Instructional Concept Guides…

  5. The NASA "Why?" Files: The Case of the "Wright" Invention. A Lesson Guide with Activities in Mathematics, Science, and Technology.

    ERIC Educational Resources Information Center

    National Aeronautics and Space Administration, Hampton, VA. Langley Research Center.

    This lesson guide for instruction of students in grades 3-5 contains activities in mathematics, science, and technology. The NASA "Why?" Files is a series of instructional programs consisting of broadcast, print, and online elements. Emphasizing standards-based instruction, Problem-Based Learning, and science as inquiry, the series seeks to…

  6. Programming Design Guide for Computer Implementation of Job Aid for Selecting Instructional Setting. Final Report.

    ERIC Educational Resources Information Center

    Schulz, Russel E.; And Others

    This Programming Design Guide (PDG) was developed to permit the offline Job Aid for Selecting Instructional Setting, which is one of 13 job aids presently available for use with the Instructional Systems Development (ISD) model, to be available in an inquiry-type, online version. It is intended to provide computer programmers with all of the…

  7. The alpha/beta hydrolase CGI-58 and peroxisomal transport protein PXA1 coregulate lipid homeostasis and signaling in Arabidopsis

    USDA-ARS?s Scientific Manuscript database

    COMPARATIVE GENE IDENTIFICATION-58 (CGI-58) is a key regulator of lipid metabolism and signaling in mammals, but its underlying mechanisms are unclear. Disruption of CGI-58 in either mammals or plants results in a significant increase in triacylglycerol (TAG), suggesting that CGI-58 activity is evol...

  8. Diesel Engine Mechanics.

    ERIC Educational Resources Information Center

    Foutes, William A.

    Written in student performance terms, this curriculum guide on diesel engine repair is divided into the following eight sections: an orientation to the occupational field and instructional program; instruction in operating principles; instruction in engine components; instruction in auxiliary systems; instruction in fuel systems; instruction in…

  9. Developmentally Programmed 3′ CpG Island Methylation Confers Tissue- and Cell-Type-Specific Transcriptional Activation

    PubMed Central

    Yu, Da-Hai; Ware, Carol; Waterland, Robert A.; Zhang, Jiexin; Chen, Miao-Hsueh; Gadkari, Manasi; Kunde-Ramamoorthy, Govindarajan; Nosavanh, Lagina M.

    2013-01-01

    During development, a small but significant number of CpG islands (CGIs) become methylated. The timing of developmentally programmed CGI methylation and associated mechanisms of transcriptional regulation during cellular differentiation, however, remain poorly characterized. Here, we used genome-wide DNA methylation microarrays to identify epigenetic changes during human embryonic stem cell (hESC) differentiation. We discovered a group of CGIs associated with developmental genes that gain methylation after hESCs differentiate. Conversely, erasure of methylation was observed at the identified CGIs during subsequent reprogramming to induced pluripotent stem cells (iPSCs), further supporting a functional role for the CGI methylation. Both global gene expression profiling and quantitative reverse transcription-PCR (RT-PCR) validation indicated opposing effects of CGI methylation in transcriptional regulation during differentiation, with promoter CGI methylation repressing and 3′ CGI methylation activating transcription. By studying diverse human tissues and mouse models, we further confirmed that developmentally programmed 3′ CGI methylation confers tissue- and cell-type-specific gene activation in vivo. Importantly, luciferase reporter assays provided evidence that 3′ CGI methylation regulates transcriptional activation via a CTCF-dependent enhancer-blocking mechanism. These findings expand the classic view of mammalian CGI methylation as a mechanism for transcriptional silencing and indicate a functional role for 3′ CGI methylation in developmental gene regulation. PMID:23459939

  10. Writing World-Wide Web CGI scripts in the REXX language

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cottrell, R.L.A.

    This talk is aimed at people who have experience with REXX and are interested in using it to write WWW CGI scripts. As part of this, the author describes several functions that are available in a library of REXX functions that simplify writing WWW CGI scripts. This library is freely available at //www.slac.standard.edu/slac/www/tool/cgi-rexx/.

  11. Designing LibGuides as Instructional Tools for Critical Thinking and Effective Online Learning

    ERIC Educational Resources Information Center

    Baker, Ruth L.

    2014-01-01

    Did you ever wish for an easy-to-maintain tool to create course-level or assignment-level instruction for online or distance students? LibGuides can provide the solution! LibGuides provide a versatile and easy-to-maintain platform for delivering step-by-step, scaffolded tutorials that enhance learning outcomes through chunking, reduced strain on…

  12. A Facilitator's Guide for the Online Course: What Education Leaders Should Know about Virtual Education

    ERIC Educational Resources Information Center

    Rukobo, Emily Zyko; Penfold, Angela; Adler, C. Ralph; Larson, Heidi; Peterson, Kirsten

    2012-01-01

    This Facilitator's Guide is based on What Education Leaders Should Know about Virtual Education, an online course designed by the Center on Instruction and the New England Comprehensive Center. The Facilitator's Guide demonstrates step-by-step how to build the course on a learning management system (LMS) and provides instructions on all phases of…

  13. Horticulture I--Course No. 6841. Horticulture II--Course No. 6842. Agricultural Education Curriculum Guide.

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Public Instruction, Raleigh. Div. of Vocational Education.

    This curriculum guide is designed to help horticulture teachers in North Carolina high schools plan and deliver instruction. The guide contains a list of the 39 competencies included in Horticulture I and the 44 competencies included in Horticulture II. It also contains five units of instruction for Horticulture I and eight units for Horticulture…

  14. Comprehensive Approach to Pupil Planning: Stage III - Instructional Planning (Includes Data Sources Within the CAPP System and Teacher's Instructional Plan). Experimental Edition.

    ERIC Educational Resources Information Center

    Vlasak, Frances Stetson; Kaufman, Martin J.

    Presented is Stage III of the Comprehensive Approach to Pupil Planning (CAPP) System, a three-stage model for planning educational interventions in the regular and special education classrooms and for guiding placement decisions. The guide focuses on the instructional planning team with sections on the following: Stage III personnel; roles and…

  15. Typewriting.

    ERIC Educational Resources Information Center

    Virginia State Dept. of Education, Richmond. Business Education Service.

    The document is a guide intended to suggest teaching methods for typewriting instruction, whether for a beginning course for students interested in personal typing or for vocational typewriting courses in occupational preparation programs. The guide outlines learning activities to supplement instruction on 34 topics from paper insertion, operating…

  16. SU-F-P-55: Testicular Scatter Dose Determination During Prostate SBRT with and Without Pelvic Lymph Nodes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Venencia, C; Garrigo, E; Castro Pena, P

    Purpose: The elective irradiation of pelvis lymph node for prostate cancer is still controversial. Including pelvic lymph node as part of the planning target volume could increase the testicular scatter dose, which could have a clinical impact. The objective of this work was to measure testicular scatter dose for prostate SBRT treatment with and without pelvic lymph nodes using TLD dosimetry. Methods: A 6MV beam (1000UM/min) produce by a Novalis TX (BrainLAB-VARIAN) equipped HDMLC was used. Treatment plan were done using iPlan v4.5.3 (BrainLAB) treatment planning system with sliding windows IMRT technique. Prostate SBRT plan (PLAN-1) uses 9 beams withmore » a dose prescription (D95%) of 4000cGy in 5 fractions. Prostate with lymph nodes SBRT plan (PLAN-2) uses 11 beams with a dose prescription (D95%) of 4000cGy to the prostate and 2500cGy to the lymph node in 5 fractions. An anthropomorphic pelvic phantom with a testicular volume was used. Phantom was positioned using ExacTrac IGRT system. Phosphor TLDs LiF:Mg, Ti (TLD700 Harshaw) were positioned in the anterior, posterior and inferior portion of the testicle. Two set of TLD measurements was done for each treatment plan. TLD in vivo dosimetry was done in one patient for each treatment plan. Results: The average phantom scatter doses per fraction for the PLAN-1 were 10.9±1cGy (anterior), 7.8±1cGy (inferior) and 10.7±1cGy (posterior) which represent an average total dose of 48±1cGy (1.2% of prostate dose prescription). The doses for PLAN-2 plan were 17.7±1cGy (anterior), 11±1cGy (inferior) and 13.3±1cGy (posterior) which represent an average total dose of 70.1±1cGy (1.8% of prostate dose prescription). The average dose for in vivo patient dosimetry was 60±1cGy for PLAN-1 and 85±1cGy for PLAN-2. Conclusion: Phantom and in vivo dosimetry shows that the pelvic lymph node irradiation with SBRT slightly increases the testicular scatter dose, which could have a clinical impact.« less

  17. Radiotherapy for gastric lymphoma: a planning study of 3D conformal radiotherapy, the half-beam method, and intensity-modulated radiotherapy.

    PubMed

    Inaba, Koji; Okamoto, Hiroyuki; Wakita, Akihisa; Nakamura, Satoshi; Kobayashi, Kazuma; Harada, Ken; Kitaguchi, Mayuka; Sekii, Shuhei; Takahashi, Kana; Yoshio, Kotaro; Murakami, Naoya; Morota, Madoka; Ito, Yoshinori; Sumi, Minako; Uno, Takashi; Itami, Jun

    2014-11-01

    During radiotherapy for gastric lymphoma, it is difficult to protect the liver and kidneys in cases where there is considerable overlap between these organs and the target volume. This study was conducted to compare the three radiotherapy planning techniques of four-fields 3D conformal radiotherapy (3DCRT), half-field radiotherapy (the half-beam method) and intensity-modulated radiotherapy (IMRT) used to treat primary gastric lymphoma in which the planning target volume (PTV) had a large overlap with the left kidney. A total of 17 patients with gastric diffuse large B-cell lymphoma (DLBCL) were included. In DLBCL, immunochemotherapy (Rituximab + CHOP) was followed by radiotherapy of 40 Gy to the whole stomach and peri-gastric lymph nodes. 3DCRT, the half-field method, and IMRT were compared with respect to the dose-volume histogram (DVH) parameters and generalized equivalent uniform dose (gEUD) to the kidneys, liver and PTV. The mean dose and gEUD for 3DCRT was higher than for IMRT and the half-beam method in the left kidney and both kidneys. The mean dose and gEUD of the left kidney was 2117 cGy and 2224 cGy for 3DCRT, 1520 cGy and 1637 cGy for IMRT, and 1100 cGy and 1357 cGy for the half-beam method, respectively. The mean dose and gEUD of both kidneys was 1335 cGy and 1559 cGy for 3DCRT, 1184 cGy and 1311 cGy for IMRT, and 700 cGy and 937 cGy for the half-beam method, respectively. Dose-volume histograms (DVHs) of the liver revealed a larger volume was irradiated in the dose range <25 Gy with 3DCRT, while the half-beam method irradiated a larger volume of liver with the higher dose range (>25 Gy). IMRT and the half-beam method had the advantages of dose reduction for the kidneys and liver. © The Author 2014. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology.

  18. Dosimetric analysis of testicular doses in prostate intensity-modulated and volumetric-modulated arc radiation therapy at different energy levels

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Onal, Cem, E-mail: hcemonal@hotmail.com; Arslan, Gungor; Dolek, Yemliha

    2016-01-01

    The aim of this study is to evaluate the incidental testicular doses during prostate radiation therapy with intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc radiotherapy (VMAT) at different energies. Dosimetric data of 15 patients with intermediate-risk prostate cancer who were treated with radiotherapy were analyzed. The prescribed dose was 78 Gy in 39 fractions. Dosimetric analysis compared testicular doses generated by 7-field intensity-modulated radiotherapy and volumetric-modulated arc radiotherapy with a single arc at 6, 10, and 15 MV energy levels. Testicular doses calculated from the treatment planning system and doses measured from the detectors were analyzed. Mean testicular doses from themore » intensity-modulated radiotherapy and volumetric-modulated arc radiotherapy per fraction calculated in the treatment planning system were 16.3 ± 10.3 cGy vs 21.5 ± 11.2 cGy (p = 0.03) at 6 MV, 13.4 ± 10.4 cGy vs 17.8 ± 10.7 cGy (p = 0.04) at 10 MV, and 10.6 ± 8.5 cGy vs 14.5 ± 8.6 cGy (p = 0.03) at 15 MV, respectively. Mean scattered testicular doses in the phantom measurements were 99.5 ± 17.2 cGy, 118.7 ± 16.4 cGy, and 193.9 ± 14.5 cGy at 6, 10, and 15 MV, respectively, in the intensity-modulated radiotherapy plans. In the volumetric-modulated arc radiotherapy plans, corresponding testicular doses per course were 90.4 ± 16.3 cGy, 103.6 ± 16.4 cGy, and 139.3 ± 14.6 cGy at 6, 10, and 15 MV, respectively. In conclusions, this study was the first to measure the incidental testicular doses by intensity-modulated radiotherapy and volumetric-modulated arc radiotherapy plans at different energy levels during prostate-only irradiation. Higher photon energy and volumetric-modulated arc radiotherapy plans resulted in higher incidental testicular doses compared with lower photon energy and intensity-modulated radiotherapy plans.« less

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pantelis, Evaggelos, E-mail: vpantelis@phys.uoa.g; Medical Physics Laboratory, Medical School, University of Athens, Athens; Papadakis, Nikolaos

    Purpose: To study the efficacy of the integration of functional magnetic resonance imaging (fMRI) and diffusion tensor imaging tractography data into stereotactic radiosurgery clinical practice. Methods and Materials: fMRI and tractography data sets were acquired and fused with corresponding anatomical MR and computed tomography images of patients with arteriovenous malformation (AVM), astrocytoma, brain metastasis, or hemangioma and referred for stereotactic radiosurgery. The acquired data sets were imported into a CyberKnife stereotactic radiosurgery system and used to delineate the target, organs at risk, and nearby functional structures and fiber tracts. Treatment plans with and without the incorporation of the functional structuresmore » and the fiber tracts into the optimization process were developed and compared. Results: The nearby functional structures and fiber tracts could receive doses of >50% of the maximum dose if they were excluded from the planning process. In the AVM case, the doses received by the Broadmann-17 structure and the optic tract were reduced to 700 cGy from 1,400 cGy and to 1,200 cGy from 2,000 cGy, respectively, upon inclusion into the optimization process. In the metastasis case, the motor cortex received 850 cGy instead of 1,400 cGy; and in the hemangioma case, the pyramidal tracts received 780 cGy instead of 990 cGy. In the astrocytoma case, the dose to the motor cortex bordering the lesion was reduced to 1,900 cGy from 2,100 cGy, and therefore, the biologically equivalent dose in three fractions was delivered instead. Conclusions: Functional structures and fiber tracts could receive high doses if they were not considered during treatment planning. With the aid of fMRI and tractography images, they can be delineated and spared.« less

  20. Contralateral Breast Dose After Whole-Breast Irradiation: An Analysis by Treatment Technique

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Williams, Terence M.; Moran, Jean M., E-mail: jmmoran@med.umich.edu; Hsu, Shu-Hui

    2012-04-01

    Purpose: To investigate the contralateral breast dose (CBD) across a continuum of breast-conservation therapy techniques. Methods and Materials: An anthropomorphic phantom was CT-simulated, and six treatment plans were generated: open tangents, tangents with an external wedge on the lateral beam, tangents with lateral and medial external wedges, a simple segment plan (three segments per tangent), a complex segmental intensity-modulated radiotherapy (IMRT) plan (five segments per tangent), and a beamlet IMRT plan (>100 segments). For all techniques, the breast on the phantom was irradiated to 5000 cGy. Contralateral breast dose was measured at a uniform depth at the center and eachmore » quadrant using thermoluminescent detectors. Results: Contralateral breast dose varied with position and was 50 {+-} 7.3 cGy in the inner half, 24 {+-} 4.1 cGy at the center, and 16 {+-} 2.2 cGy in the outer half for the open tangential plan. Compared with an average dose of 31 cGy across all points for the open field, the average doses were simple segment 32 cGy (range, 99-105% compared with open technique), complex segment 34 cGy (range, 103-117% compared with open technique), beamlet IMRT 34 cGy (range, 103-124% compared with open technique), lateral wedge only 46 cGy (range, 133-175% compared with open technique), and medial and lateral wedge 96 cGy (range, 282-370% compared with open technique). Conclusions: Single or dual wedge techniques resulted in the highest CBD increases compared with open tangents. To obtain the desired homogeneity to the treated breast while minimizing CBD, segmental and IMRT techniques should be encouraged over external physical compensators.« less

  1. Archery: A Planning Guide for Group and Individual Instruction.

    ERIC Educational Resources Information Center

    American Association for Health, Physical Education, and Recreation, Washington, DC.

    This instructor's manual for group or individual instruction in archery includes line drawings as illustrations. The manual advances from facilities to beginning instruction and general instructional practices (safety tips, instructional aids, archery etiquette) to intermediate instruction (discussions of causes of faulty arrow flight, analysis of…

  2. Floating Gate sensor for in-vivo dosimetry in radiation therapies. Design and first characterization.

    NASA Astrophysics Data System (ADS)

    Faigon, A.; Martinez Vazquez, I.; Carbonetto, S.; García Inza, M.; G

    2017-01-01

    A floating gate dosimeter was designed and fabricated in a standard CMOS technology. The design guides and characterization are presented. The characterization included the controlled charging by tunneling of the floating gate, and its discharging under irradiation while measuring the transistor drain current whose change is the measure of the absorbed dose. The resolution of the obtained device is close to 1 cGy satisfying the requirements for most radiation therapies dosimetry. Pending statistical proofs, the dosimeter is a potential candidate for wide in-vivo control of radiotherapy treatments.

  3. Idaho Driver Education Instructional Guide. Revised.

    ERIC Educational Resources Information Center

    Idaho State Dept. of Education, Boise.

    This driver education instructional safety guide is organized in three sections: Driver Education; Motorcycle Education; and Driver Education for the Handicapped. The driver education section contains 10 units dealing with the following topics: parent orientation; student orientation; basic control skills; driver performance; driving regulations;…

  4. Curriculum Guide for Adult Education Teachers.

    ERIC Educational Resources Information Center

    Hammett, Earl Lee

    This curriculum guide for teachers of adult education is divided into three parts. The first offers an overview of adult basic education, the teacher as counselor, testing and evaluation, instructional procedures--physical environment and classroom management, techniques providing variety in instruction--discussions, demonstrations, projects,…

  5. Career Opportunities Instructional Guide. Career Investigation. Revised.

    ERIC Educational Resources Information Center

    Hendrix, Mary; Cegiel, Linda

    This instructional guide on career opportunities contains 17 units on the following topics: locating information about occupations; introduction to the occupational clusters; agribusiness and natural resources; business and office; communications and media; construction; consumer and homemaking; environment; fine arts and humanities; health;…

  6. Fashion Merchandising Guide.

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Public Instruction, Raleigh. Div. of Vocational Education Services.

    Developed to address the needs of the apparel industry, this fashion merchandising curriculum guide is designed to assist marketing educators in effective instructional delivery. Introductory materials include the following: a course blueprint that illustrates units of instruction, core competencies in each unit, and specific objectives for each…

  7. Questions, Instructions, and Modes of Listening in the Joint Production of Guided Action: A Study of Student-Teacher Collaboration in Handicraft Education

    ERIC Educational Resources Information Center

    Ekstrom, Anna; Lindwall, Oskar; Saljo, Roger

    2009-01-01

    This article concerns a central issue in education as an institutional activity: instructions and their role in guiding student activities and understanding. In the study, we investigate the tensions between specifics and generalities in the joint production of guided action. This issue is explored in the context of handicraft education--or more…

  8. New Instructional Materials on Africa South of the Sahara (1969-1970). A Supplement to Africa South of the Sahara: A Resource and Curriculum Guide.

    ERIC Educational Resources Information Center

    Beyer, Barry K.

    This guide cites instructional materials on Africa south of the Sahara which have become available since February 1969. Acknowledging the probability of inaccuracies in the majority of the materials cited, the guide neither evaluates nor promotes items, but simply presents annotations of readings, textbooks, fact sheets, atlases, African…

  9. Guide d'enseignement du francais au secondaire. Volet I: Comprehension ecrite. Immersion (Teaching Guide for French at the Secondary Level. Part I: Reading Comprehension. Immersion).

    ERIC Educational Resources Information Center

    Leduc, Denise

    This guide to secondary school French reading instruction addresses a variety of general and specific instructional issues. An introductory chapter discusses program objectives, minimum program requirements, and the population to be taught. The second chapter looks at theoretical aspects of the development of reading ability: current thoughts on…

  10. Prescribing Patterns in a Psychiatrically Referred Sample of Youth With Autism Spectrum Disorder.

    PubMed

    Shekunov, Julia; Wozniak, Janet; Conroy, Kristina; Pinsky, Elizabeth; Fitzgerald, Maura; de Leon, Melissa F; Belser, Abigail; Biederman, Joseph; Joshi, Gagan

    The aim of this study was to examine the pattern of psychopharmacologic interventions in a psychiatrically referred sample of youth with autism spectrum disorder (ASD). This retrospective chart review aimed at collecting demographic and clinical information, including data on DSM-IV-TR criteria-based psychiatric disorders and related current medication treatment and response. Data were collected in December 2011. Clinicians identified the target disorder for each medication and any adverse events. Level of psychopathology and therapeutic response was assessed by the clinician-rated Clinical Global Impressions scale (CGI). Psychiatrically referred youth with ASD (n = 54) suffered from multiple psychopathologies (mean = 2.3) and had a marked level of morbidity (range of baseline CGI-Severity of Illness mean scores, 4.3-5.6). The most prevalent psychopathology was ADHD (83%), anxiety disorders (67%), bipolar spectrum disorder (43%), and mood disorder not otherwise specified (44%). The majority (80%) of the subjects received combination therapy (mean ± SD number of psychotropic medications = 3 ± 1.5). Forty percent of the participants responded on all treatment target symptoms (CGI-Improvement scale score ≤ 2), and an additional 10% experienced response versus nonresponse on a relatively greater number of target symptoms. Half of the subjects reported an adverse event, most commonly weight gain (28%) and sedation (12%), both from antipsychotic medication use. Psychiatrically referred youth with ASD suffer from multiple highly impairing psychiatric disorders that require combination pharmacotherapy. These findings highlight the need for further research to guide clinical decision-making and treatment. © Copyright 2017 Physicians Postgraduate Press, Inc.

  11. Computational ghost imaging using deep learning

    NASA Astrophysics Data System (ADS)

    Shimobaba, Tomoyoshi; Endo, Yutaka; Nishitsuji, Takashi; Takahashi, Takayuki; Nagahama, Yuki; Hasegawa, Satoki; Sano, Marie; Hirayama, Ryuji; Kakue, Takashi; Shiraki, Atsushi; Ito, Tomoyoshi

    2018-04-01

    Computational ghost imaging (CGI) is a single-pixel imaging technique that exploits the correlation between known random patterns and the measured intensity of light transmitted (or reflected) by an object. Although CGI can obtain two- or three-dimensional images with a single or a few bucket detectors, the quality of the reconstructed images is reduced by noise due to the reconstruction of images from random patterns. In this study, we improve the quality of CGI images using deep learning. A deep neural network is used to automatically learn the features of noise-contaminated CGI images. After training, the network is able to predict low-noise images from new noise-contaminated CGI images.

  12. Strategy Instruction in Mathematics.

    ERIC Educational Resources Information Center

    Goldman, Susan R.

    1989-01-01

    Experiments in strategy instruction for mathematics have been conducted using three models (direct instruction, self-instruction, and guided learning) applied to the tasks of computation and word problem solving. Results have implications for effective strategy instruction for learning disabled students. It is recommended that strategy instruction…

  13. CGI-99 promotes breast cancer metastasis via autocrine interleukin-6 signaling.

    PubMed

    Lin, C; Liao, W; Jian, Y; Peng, Y; Zhang, X; Ye, L; Cui, Y; Wang, B; Wu, X; Xiong, Z; Wu, S; Li, J; Wang, X; Song, L

    2017-06-29

    Metastatic relapse remains largely incurable and a major challenge of clinical management in breast cancer, but the underlying mechanisms are poorly understood. Herein, we report that CGI-99 is overexpressed in breast cancer tissues from patients with metastatic recurrence within 5 years. High CGI-99 significantly predicts poorer 5-year metastasis-free patient survival. We find that CGI-99 increases breast cancer stem cell properties, and potentiates efficient tumor lung colonization and outgrowth in vivo. Furthermore, we demonstrate that CGI-99 activates the autocrine interleukin-6 (IL-6)/STAT3 signaling by increasing the accumulation and activity of RNA polymerase II and p300 cofactor at the proximal promoter of IL-6. Importantly, delivery of the IL-6-receptor humanized monoclonal antibody tocilizumab robustly abrogates CGI-99-induced metastasis in vivo. Finally, we find that high levels of CGI-99 are significantly correlated with STAT3 hyperactivation in breast cancer patients. These findings reveal a potential mechanism for constitutive activation of autocrine IL-6/STAT3 signaling and may suggest a novel target for clinical intervention in breast cancer.

  14. 78 FR 58567 - Criteria to Certify Coal Mine Rescue Teams

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-24

    ... to Certify Coal Mine Rescue Teams AGENCY: Mine Safety and Health Administration, Labor. ACTION...) is requesting comments on revised instruction guides for coal mine rescue team training. MSHA prescribes training materials through the issuance of instruction guides. Existing standards for coal mine...

  15. Electrical Mechanical Maintenance. Instructor's Guide.

    ERIC Educational Resources Information Center

    Santa Clara County Superintendent of Schools, San Jose, CA.

    This instructor's guide describes the development of a sixteen-week postsecondary course in electrical mechanical maintenance. Following introductory sections that provide background information and a course summary, the third section describes the instructional model used in the course. Section 4 presents an overview of instructional media used…

  16. REACH. Teacher's Guide, Volume I. Secondary Program Management.

    ERIC Educational Resources Information Center

    Morris, James Lee; And Others

    Designed for use with individualized instructional units (CE 026 345 and CE 026 348-350) in the REACH (Refrigeration, Electro-Mechanical, Air-Conditioning, Heating) electromechanical cluster, this secondary teacher's guide is devoted to the establishment of standard instructional procedures. Following an introductory section, sections provide…

  17. Learning Resources and Technology. A Guide to Program Development.

    ERIC Educational Resources Information Center

    Connecticut State Dept. of Education, Hartford.

    This guide provides a framework to assist all Connecticut school districts in planning effective learning resources centers and educational technology programs capable of providing: a well developed library media component; shared instructional design responsibilities; reading for enrichment; integration of computers into instruction; distance…

  18. General Electronics Technician: Basic Electronics.

    ERIC Educational Resources Information Center

    Hilley, Robert

    These instructional materials include a teacher's guide designed to assist instructors in organizing and presenting an introductory course in general electronics and a student guide. The materials are based on the curriculum-alignment concept of first stating the objectives, developing instructional strategies for teaching those objectives, and…

  19. 7 CFR 3430.17 - Content of an application.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... RFA, as well as the application instructions. The application instructions document, “NIFA Grants.gov Application Guide: A Guide for Preparation and Submission of NIFA Applications via Grants.gov,” is intended to... document for use in the preparation of NIFA applications via Grants.gov. ...

  20. 7 CFR 3430.17 - Content of an application.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... RFA, as well as the application instructions. The application instructions document, “NIFA Grants.gov Application Guide: A Guide for Preparation and Submission of NIFA Applications via Grants.gov,” is intended to... document for use in the preparation of NIFA applications via Grants.gov. ...

  1. 7 CFR 3430.17 - Content of an application.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... RFA, as well as the application instructions. The application instructions document, “NIFA Grants.gov Application Guide: A Guide for Preparation and Submission of NIFA Applications via Grants.gov,” is intended to... document for use in the preparation of NIFA applications via Grants.gov. ...

  2. Commercial Carpentry. Instructor Edition.

    ERIC Educational Resources Information Center

    Hendrix, Laborn J.

    This teaching guide is intended to combine practical experience in the construction industry with the teaching methods of vocational education for instruction in carpentry. Instructional material in this manual is written in terms of student performance, using measurable behavioral objectives. This guide contains 4 sections organized in 24…

  3. Problem Solving with Guided Repeated Oral Reading Instruction

    ERIC Educational Resources Information Center

    Conderman, Greg; Strobel, Debra

    2006-01-01

    Many students with disabilities require specialized instructional interventions and frequent progress monitoring in reading. The guided repeated oral reading technique promotes oral reading fluency while providing a reliable data-based monitoring system. This article emphasizes the importance of problem-solving when using this reading approach.

  4. Apparel. Teacher's Instructional Guide.

    ERIC Educational Resources Information Center

    Rambo, Patti

    This instructional guide for a one-half credit technological laboratory course for grades 10-12 focuses on apparel from the perspectives of personal decision making related to apparel, the apparel industry, and career preparation. Introductory materials are a course description; overview of course design; facilities, equipment, and resources; and…

  5. A State Articulated Instructional Objectives Guide for Occupational Education Programs. State Pilot Model for Drafting (Graphic Communications). Part I--Basic. Part II--Specialty Programs. Section A (Mechanical Drafting and Design). Section B (Architectural Drafting and Design).

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Community Colleges, Raleigh.

    A two-part articulation instructional objective guide for drafting (graphic communications) is provided. Part I contains summary information on seven blocks (courses) of instruction. They are as follow: introduction; basic technical drafting; problem solving in graphics; reproduction processes; freehand drawing and sketching; graphics composition;…

  6. Mathematics Curriculum Guide for Spanish-Speaking Students, Levels E, F. Field Test. Working Draft = Guia didactica de matematicas, Niveles E, F. Edicion Experimental.

    ERIC Educational Resources Information Center

    Chicago Board of Education, IL. Dept. of Curriculum.

    The curriculum guide for mathematics instruction in the bilingual education program of the Chicago public schools is designed to assist teachers in the instruction of limited-English-speaking students in their native language. The guide outlines, for each of two levels, lessons on absolute and relative values of numbers, whole number operations,…

  7. A Competency-Based Instructional Program for Plant Process Operations.

    ERIC Educational Resources Information Center

    McDaniel, Joy; Mills, Steven

    This program guide provides materials to prepare learners for employment as Process Plant Operators through classroom instruction and practical shop experience. Contents include instructional goal and subgoals, an instructional analysis that describes development of the materials and instructional equipment and supplies and facilities…

  8. Computer-Assisted Instruction Case Study: The Introductory Marketing Course.

    ERIC Educational Resources Information Center

    Skinner, Steven J.; Grimm, Jim L.

    1979-01-01

    Briefly reviews research on the effectiveness of CAI in instruction, and describes a study comparing the performance of students using one program for basic marketing--TRMP (Tutorial Review of Marketing Principles)--with or without a study guide, the study guide alone, and a traditional class. (BBM)

  9. Biology II Curriculum Guide. Bulletin 1820.

    ERIC Educational Resources Information Center

    Louisiana State Dept. of Education, Baton Rouge. Div. of Academic Programs.

    In 1986, the Louisiana State Board of Elementary and Secondary Education requested that an advanced course in Biology II be developed. The resulting curriculum guide contains grade appropriate goals, skills, and competencies; suggested activities; suggested materials of instruction; and minimum time allotments for instruction. Biology II is a…

  10. Management. Teacher's Instructional Guide.

    ERIC Educational Resources Information Center

    Hutnyak, Dana

    This teacher's instructional guide, which is part of a family and consumer sciences education series focusing on a broad range of employment opportunities, is intended to assist teachers responsible for teaching one- and two-year management programs for Texas high school students. The following are among the items included: (1) introductory…

  11. Exploring Technology Education: Exploring Communication Technology.

    ERIC Educational Resources Information Center

    Joerschke, John D.

    These instructional materials include a teacher's guide designed to assist instructors in organizing and presenting a unit of study on communication technology and a student guide. The materials are based on the curriculum-alignment concept of first stating the objectives, developing instructional strategies for teaching those objectives, and then…

  12. Individualized Materials for the Handicapped: A Guide for Selection.

    ERIC Educational Resources Information Center

    Eastern Pennsylvania Regional Resources Center for Special Education, King of Prussia.

    Intended for teachers of the handicapped, the booklet provides a guide for choosing individualized instructional materials. Materials are noted to generally fall into six program categories: reading, mathematics, language arts, social studies, science, and other resources. Information on each instructional kit/program (listed alphabetically under…

  13. VoCATS User Guide. [Draft.

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Public Instruction, Raleigh. Div. of Vocational Education Services.

    This guide focuses on use of the North Carolina Vocational Competency Achievement Tracking System (VoCATS)-designated software in the instructional management process. (VoCATS is a competency-based, computer-based instructional management system that allows the collection of data on student performance achievement prior to, during, and following…

  14. Exploring Agriculture in America. Instructor Guide and Student Reference.

    ERIC Educational Resources Information Center

    Humphrey, John Kevin; And Others

    This curriculum guide is designed to provide instruction about agriculture for eighth-grade students in Missouri. Lessons included in the curriculum employ a problem-solving instructional approach. Student-oriented activities are included to provide opportunities for experiential learning. Core competencies and key skills are identified in…

  15. Articulated, Performance-Based Instruction Objectives Guide for Automotive Mechanics. Final Document. Revised.

    ERIC Educational Resources Information Center

    Henderson, William Edward, Jr.

    Developed during a project designed to provide continuous, performance-based vocational training at the secondary and postsecondary levels, this instructional guide is intended to help teachers implement a laterally and vertically articulated secondary level automotive mechanics program. Introductory materials include descriptions of Automotive…

  16. Exploring Technology Education: Introduction to Technology Education.

    ERIC Educational Resources Information Center

    Joerschke, John D.

    These instructional materials include a teacher's guide designed to assist instructors in organizing and presenting an introductory course in technology education and a student guide. The materials are based on the curriculum-alignment concept of first stating the objectives, developing instructional strategies for teaching those objectives, and…

  17. Pennsylvania Industrial Arts Safety Guide. Second Edition.

    ERIC Educational Resources Information Center

    Graham, Charles D., Ed.

    Intended to alert industrial arts teachers, teacher educators, school administrators, and industrial arts supervisors to the importance of a strong safety program, this guide provides the instructional resources for instituting safety instruction in the public schools, for the inservice training of industrial arts teachers, and for the education…

  18. Exploring Technology Education: Exploring Manufacturing Technology.

    ERIC Educational Resources Information Center

    Joerschke, John D.

    These instructional materials include a teacher's guide designed to assist instructors in organizing and presenting a unit of study on manufacturing technology and a student guide. The materials are based on the curriculum-alignment concept of first stating the objectives, developing instructional strategies for teaching those objectives, and then…

  19. Research Support for the Instructional Strategy Diagnostic Profile. Technical Report No. 3

    ERIC Educational Resources Information Center

    Merrill, M. David; And Others

    By using a taxonomy of instructional strategy variables, an Instructional Strategy Diagnostic Profile (ISDP) was developed which can be used either to determine a judged index of instructional effectiveness for a previously designed instructional product or to guide the design and development of a new instructional product. Existing experimental…

  20. Characterization of radiation-induced emesis in the ferret

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    King, G.L.

    1988-06-01

    Forty-eight ferrets (Mustela putorius furo) were individually head-shielded and radiated with bilateral /sup 60/Co gamma radiation at 100 cGy min-1 at doses ranging between 49 and 601 cGy. The emetic threshold was observed at 69 cGy, the ED50 was calculated at 77 cGy, and 100% incidence of emesis occurred at 201 cGy. With increasing doses of radiation, the latency to first emesis after radiation decreased dramatically, whereas the duration of the prodromal period increased. Two other sets of experiments suggest that dopaminergic mechanisms play a minor role in radiation-induced emesis in the ferret. Twenty-two animals were injected either intravenously ormore » subcutaneously with 30 to 300 micrograms/kg of apomorphine. Fewer than 50% of the animals vomited to 300 micrograms/kg apomorphine; central dopaminergic receptor activation was apparent at all doses. Another eight animals received 1 mg/kg domperidone prior to either 201 (n = 4) or 401 (n = 4) cGy radiation and their emetic responses were compared with NaCl-injected-irradiated controls (n = 8). At 201 cGy, domperidone significantly reduced only the total time in emetic behavior. At 401 cGy, domperidone had no salutary effect on radiation-induced emesis. The emetic responses of the ferret to radiation and apomorphine are compared with these responses in other vomiting species.« less

  1. Characterization of radiation-induced emesis in the ferret

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    King, G.L.

    1988-01-01

    Forty-eight ferrets (Mustela putorius furo) were individually head-shielded and radiated with bilateral cobalt 60 gamma radiation at 100 cGy min at doses ranging between 49 and 601 cGy. The emetic threshold was observed at 69 cGy, the ED 50 was calculated as 77 cGy, and 100% incidence of emesis occurred at 201 cGy. With increasing doses of radiation, the latency to first emesis after radiation decreased dramatically, whereas the duration of the prodromal period increased. Two other sets of experiments suggest that dopaminergic mechanisms play a minor role in radiation-induced emesis in the ferret. Twenty-two animals were injected either intravenouslymore » or subcutaneously with 30 to 300 micrograms /kg of apomorphine. Fewer than 50% of the animals vomited to 300 micrograms/kg apomorphine; central dopaminergic receptor activation was apparent at all doses. Another eight animals received 1 mg/kg domperidone prior to either 201 (n=4) or 401 (n=4) cGy radiation and their emetic responses were compared with NaCi-injected-irradiated controls (n=8). At 201 cGy, domperidone significantly reduced only the total time in emetic behavior. At 401 cGy, domperidone had no salutary effect on radiation-induced emesis. The emetic responses of the ferret to radiation and apomorphine are compared with these responses in other vomiting species.« less

  2. Integrated Baseline System (IBS). Version 1.03, System Management Guide

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Williams, J.R.; Bailey, S.; Bower, J.C.

    This IBS System Management Guide explains how to install or upgrade the Integrated Baseline System (IBS) software package. The IBS is an emergency management planning and analysis tool that was developed under the direction of the Federal Emergency Management Agency (FEMA). This guide includes detailed instructions for installing the IBS software package on a Digital Equipment Corporation (DEC) VAX computer from the IBS distribution tapes. The installation instructions include procedures for both first-time installations and upgrades to existing IBS installations. To ensure that the system manager has the background necessary for successful installation of the IBS package, this guide alsomore » includes information on IBS computer requirements, software organization, and the generation of IBS distribution tapes. When special utility programs are used during IBS installation and setups, this guide refers you to the IBS Utilities Guide for specific instructions. This guide also refers you to the IBS Data Management Guide for detailed descriptions of some IBS data files and structures. Any special requirements for installation are not documented here but should be included in a set of installation notes that come with the distribution tapes.« less

  3. Instructional Gaming: Implications for Instructional Technology.

    ERIC Educational Resources Information Center

    Dempsey, John V.; And Others

    Instructional gaming, as distinguished from simulation, is defined as any overt instructional or learning format that involves competition and is rule-guided. The literature review identifies five categories of articles on instructional gaming: (1) research, (2) theory, (3) reviews, (4) discussion, and (5) development. Games have been found to…

  4. REACH. Teacher's Guide, Volume I. Post-Secondary Program Management.

    ERIC Educational Resources Information Center

    Morris, James Lee; And Others

    Designed for use with individualized instruction units (CE 026 345-347, and CE 026 349-351) in the REACH (Refrigeration, Electro-Mechanical, Air-Conditioning, Heating) electromechanical cluster, this first volume of the postsecondary teacher's guide is devoted to the establishment of standard instructional procedures. Following an introductory…

  5. Computer Applications in Instruction: A Teacher's Guide to Selection and Use.

    ERIC Educational Resources Information Center

    Edwards, Judith B.; And Others

    Intended for upper elementary and secondary teachers in all subject areas, this guide provides practical advice on determining the appropriate application of computer technology and on the selection of specific, subject-related computer-based instruction units. Under the heading of hardware and software, topics discussed include communicating with…

  6. Guide for Multicultural Education: Content and Context.

    ERIC Educational Resources Information Center

    California State Dept. of Education, Sacramento. Bureau of Intergroup Relations.

    This guide explores the rationale for multicultural education at the elementary and secondary levels, its needs and goals, the school setting it requires, and the necessary processes of instructional planning and staff preparation. The basic aim of a multicultural instructional program is to help students to accept themselves and other persons as…

  7. Articulated, Performance-Based Instruction Guide for Drafting II. Final Document. Revised.

    ERIC Educational Resources Information Center

    Henderson, William Edward, Jr.

    Developed during a project designed to provide continuous, performance-based vocational training at the secondary and postsecondary levels, this instructional guide is intended to help teachers implement a laterally and vertically articulated secondary level drafting II program. Introductory materials include a description of Drafting II,…

  8. Curriculum Guide Functional Level A Exceptional Child Program.

    ERIC Educational Resources Information Center

    Pinellas County District School Board, Clearwater, FL.

    Presented is the Pinellas County, Florida, curriculum guide for the instruction of educable mentally handicapped 6- and 9-year-old children. Subject areas included are language arts, mathematics, social studies, science, health, safety, physical education, art, and music. Instructional objectives for each subject area are listed with one or more…

  9. Resource Guide: Selected Early Childhood/Early Intervention Training Materials. 8th Edition.

    ERIC Educational Resources Information Center

    Catlett, Camille, Comp.; Winton, Pamela J., Comp.

    This resource guide is intended to identify both primary and supplementary resources for designing preservice and inservice training on early intervention programs for children with disabilities. The instructional materials are described and listed in three sections. The first section provides annotated descriptions of instructional materials in…

  10. Beginning English: An Instructional Guide for ESL Teachers.

    ERIC Educational Resources Information Center

    Brower, Lynne

    An instructional guide for English as a Second Language (ESL) teachers is presented in this volume. The 18-week program contains the following modules, each of which includes sections on civics and structure: human relations; general information; housing; consumer education (money, banking, and shopping modules); occupations; health (two modules…

  11. Articulated, Performance-Based Instruction Objectives Guide for Welding. Final Document. Revised.

    ERIC Educational Resources Information Center

    Henderson, William Edward, Jr.

    Developed during a project designed to provide continuous, performance-based vocational training at the secondary and postsecondary levels, this instructional guide is intended to help teachers implement a laterally and vertically articulated secondary level welding program. Introductory materials include descriptions of Welding I and II,…

  12. ILGWU Worker-Family Education Program Curriculum Guide, 1989-1990.

    ERIC Educational Resources Information Center

    Freeman, Deidre; LaMar, Maureen

    This teacher's guide for the International Ladies' Garment Workers' Union (ILGWU) educational program provides background information, instructional materials, and instructional techniques for teaching a course in job skills and issues, with emphasis on the development of English language skills. The course is made available to union members and…

  13. Bricklaying Curriculum: Advanced Bricklaying Techniques. Instructional Materials. Revised.

    ERIC Educational Resources Information Center

    Turcotte, Raymond J.; Hendrix, Laborn J.

    This curriculum guide is designed to assist bricklaying instructors in providing performance-based instruction in advanced bricklaying. Included in the first section of the guide are units on customized or architectural masonry units; glass block; sills, lintels, and copings; and control (expansion) joints. The next two units deal with cut,…

  14. Agriculture Education. Soybeans and Rice.

    ERIC Educational Resources Information Center

    Stuttgart Public Schools, AR.

    This curriculum guide is designed for group instruction of secondary students enrolled in one or two semester-long courses in agricultural education. The guide presents units of study in the following areas: (1) soybeans, (2) rice, and (3) orientation. Each of the 17 units of instruction follows a typical format: terminal objective, specific…

  15. Foods from an Iowa Farm. A Resource Guide.

    ERIC Educational Resources Information Center

    Iowa State Dept. of Agriculture and Land Stewardship, Des Moines.

    Prepared for elementary and secondary teachers, this guide provides an annotated list of 72 instructional materials for teaching about farming and the products of Iowa farms. Entries, listed under the organization that provides the materials, state type of instructional material, major topics addressed, grades for which materials are appropriate,…

  16. Competency-Based Adult Education: A Guide to Classroom Management.

    ERIC Educational Resources Information Center

    Guglielmino, Lucy M.; And Others

    Developed as part of a 310 Special Demonstration and Teacher Training Project undertaken at Brevard Community College in 1984-85, this training guide for new Competency-Based Adult Education (CBAE) teachers offers information on the CBAE concept, individualized instruction, selection of instructional materials, student orientation, and procedures.…

  17. The Instructional Guide for Abbott Skills Enhancement Classes. Revised Edition.

    ERIC Educational Resources Information Center

    Ballinger, Ronda; Gee, Mary Kay

    This guide, which integrates adult basic education (ABE) curriculum, job skills for Abbott Laboratories, and work-related foundation skills, is designed for an instructional program in the skill areas of reading, writing, oral communications, mathematics, and problem solving. In addition to creating a uniform process and product to promote…

  18. Human Self-Development: Our Moral Heritage.

    ERIC Educational Resources Information Center

    Department of the Army, Washington, DC.

    An instructor's guide and lesson plans for classroom instruction of women in the Army's Human Self-Development Program are provided. The topic of this pamphlet is "Our Moral Heritage." Each of the six chapters of the guide have the same format, as follows: Outline, Instructor's Resource Material, Lesson Plan, and Instructional Aids. The…

  19. Emergency Management Instruction. Instructor's Guide for Grades 7-9.

    ERIC Educational Resources Information Center

    North Carolina State Div. of Emergency Management, Raleigh.

    Emergency Management education seeks to give students basic information about natural and man-made disasters, preparedness procedures, and survival techniques. The intent of this guide is to aid teachers in presenting disaster survival instruction in the junior high school grades. The materials are designed to supplement existing curricula, where…

  20. Child Development. Teacher's Instructional Guide.

    ERIC Educational Resources Information Center

    Cheatham, Joyce

    This teacher's instructional guide, which is part of a family and consumer sciences education series focusing on a broad range of employment opportunities, is intended to assist teachers responsible for teaching one- and two-year child development programs for Texas high school students. The following are among the items included: (1) introductory…

  1. Masonry. Teacher's Guide. Building Maintenance Units of Instruction.

    ERIC Educational Resources Information Center

    Barnes, Bill

    This teaching guide on masonry building maintenance, one in a series of six publications designed for building maintenance instructors in Texas, is designed to give students an understanding of masonry construction. Introductory material provides teachers with information on use of the units of instruction and personalization and localization of…

  2. Articulated, Performance-Based Instruction Objectives Guide for Building Construction/Carpentry. Final Document. Revised.

    ERIC Educational Resources Information Center

    Henderson, William Edward, Jr.

    Developed during a project designed to provide continuous, performance-based vocational training at the secondary and postsecondary levels, this instructional guide is intended to help teachers implement a laterally and vertically articulated secondary level building construction/carpentry program. Introductory materials include descriptions of…

  3. Interior Design: Teacher's Instructional Guide.

    ERIC Educational Resources Information Center

    Hays, Tricia

    This teacher's instructional guide, which is part of a family and consumer sciences education series focusing on a broad range of employment opportunities, is intended to assist teachers responsible for teaching one- and two-year interior design programs for Texas high school students. The following are among the items included: (1) introductory…

  4. Health, An Instructional Guide, Junior High School.

    ERIC Educational Resources Information Center

    Los Angeles City Schools, CA. Div. of Instructional Planning and Services.

    This teacher's guide was designed to be used with a one semester course required during the seventh grade to meet the graduation requirement for health instruction. Broad topics included are: growing and maturing; achieving personal health; food for growth and health; addicting, habit-forming, and other harmful substances; community health; and…

  5. Music Program for Idaho Elementary Schools, Grades One to Six.

    ERIC Educational Resources Information Center

    Burda, Bert A.; And Others

    This guide to music instruction for grades one-six and for special education classes provides practical, more than theoretical activities to aid the classroom teacher. The guide, stipulating no less than one-hundred minutes per week on music instruction, outlines the responsibilities of superintendents, principals, music supervisors, music…

  6. Computer-Assisted Instruction Guide.

    ERIC Educational Resources Information Center

    Entelek, Inc., Newburyport, MA.

    Provided is a compilation of abstracts of currently available computer-assisted instructional (CAI) programs. The guide contains the specifications of all operational CAI programs that have come under the surveillance of ENTELEK's CAI Information Exchange since its establishment in 1965. A total of 226 CAI programs by 160 authors at 38 CAI centers…

  7. Vocational Curriculum Resources for Handicapped Students. A Guide to Print and Non-Print Instructional Materials.

    ERIC Educational Resources Information Center

    Mangano, R. Michael; And Others

    This guide to vocational curriculum resources for handicapped students consists of instructional checklists for resources identified in the following areas: agriculture, auto body repair, automobile mechanics, basic math skills, basic reading skills, business education, career education, carpentry, cosmetology, custodial and maintenance, data…

  8. General Metal Trades Book I. Units of Instruction. Teacher's Guide.

    ERIC Educational Resources Information Center

    East Texas State Univ., Commerce. Occupational Curriculum Lab.

    This teacher's guide provides instructional materials for a 10-unit course in the General Metal Trades program. Each unit includes most or all of these basic components: performance objectives (unit and specific objectives), suggested teaching activities (a sheet outlining steps to follow to accomplish specific objectives), information sheets,…

  9. Foods and Nutrition. In-Depth Curriculum.

    ERIC Educational Resources Information Center

    Truitt, Debbie

    This foods and nutrition curriculum guide is designed for eleventh and twelfth grade consumer and homemaking students who have had two years of previous vocational home economics. The guide contains four sections and eight instructional units. Section 1, Food-Related Careers, contains one instructional unit on employment in food-related…

  10. Facility Programming and Construction Criteria [Planning Guide]. 702 KAR 4:170.

    ERIC Educational Resources Information Center

    Kentucky State Dept. of Education, Frankfort. Div. of Facilities Management.

    This facility construction planning guide presents the minimum instructional space standards for Kentucky's public school system. It provides definitions of terms found in the regulations; presents space requirements for every type of instructional space within a public school, including circulation areas, storage, and mechanical/electrical areas;…

  11. Health Concepts, Guides for Health Instruction.

    ERIC Educational Resources Information Center

    American Association for Health, Physical Education, and Recreation, Washington, DC.

    Concepts and supporting data pertaining to major health problems facing youth today as well as those anticipated in the next decade are enumerated in this resource. The material is designed as a reference for curriculum planners and classroom teachers in developing curriculum and teaching guides, units and instruction, and other curriculum…

  12. A Practical Guide to Early Numeracy Instruction for General and Special Educators

    ERIC Educational Resources Information Center

    Anderson, Alida

    2013-01-01

    This report summarizes recommendations from NCTM, NRC, CCSSM, NMAP, and IES to guide early numeracy instruction for elementary age students in general and special education classroom settings. We highlight common threads among general and special education research recommendations and provide a numeracy intervention curriculum model connecting…

  13. Expanding Library Services and Instruction Through LibGuides.

    PubMed

    Ream, Tim; Parker-Kelly, Darlene

    2016-01-01

    Beginning in 2012, the Charles R. Drew University (CDU) Health Sciences Library used LibGuides in a number of innovative ways. Librarians constructed e-book databases, in-depth tutorials on technology-related topics, and web pages highlighting special events. To assess similar LibGuides innovation, CDU librarians developed an eight-question survey distributed to health sciences and hospital libraries throughout Southern California and Arizona. Results showed that libraries used LibGuides primarily to deliver access to online resources and to provide supplementary materials supporting instruction. Responses also revealed that many libraries had not yet adopted LibGuides. These findings were analyzed and compared to past and current LibGuides design at CDU.

  14. Communication Arts: A Tentative Curriculum Guide for English 7-12, Basic, Regular, STS, [Advanced], Junior High Speech A & B, Speech I and II, Drama I and II, and Journalism I and II.

    ERIC Educational Resources Information Center

    Irving Independent School District, TX.

    This guide is intended to be used for instruction in communication skills from the seventh grade through the twelfth. Each section of the guide is identified by grade level and includes instructional objectives, suggestions for introducing and motivating the unit, required material, suggested activities, audiovisual aids, resource materials, and…

  15. Motivational Measure of the Instruction Compared: Instruction Based on the ARCS Motivation Theory vs Traditional Instruction in Blended Courses

    ERIC Educational Resources Information Center

    Colakoglu, Ozgur M.; Akdemir, Omur

    2012-01-01

    The ARCS Motivation Theory was proposed to guide instructional designers and teachers who develop their own instruction to integrate motivational design strategies into the instruction. There is a lack of literature supporting the idea that instruction for blended courses if designed based on the ARCS Motivation Theory provides different…

  16. Explicit Instruction Elements in Core Reading Programs

    ERIC Educational Resources Information Center

    Child, Angela R.

    2012-01-01

    Classroom teachers are provided instructional recommendations for teaching reading from their adopted core reading programs (CRPs). Explicit instruction elements or what is also called instructional moves, including direct explanation, modeling, guided practice, independent practice, discussion, feedback, and monitoring, were examined within CRP…

  17. Skeletal muscle PLIN proteins, ATGL and CGI-58, interactions at rest and following stimulated contraction

    PubMed Central

    Ramos, Sofhia V.; Vandenboom, Rene; Roy, Brian D.; Peters, Sandra J.

    2013-01-01

    Evidence indicates that skeletal muscle lipid droplet-associated proteins (PLINs) regulate lipolysis through protein-protein interactions on the lipid droplet surface. In adipocytes, PLIN1 is thought to regulate lipolysis by directly interacting with comparative gene identification-58 (CGI-58), an activator of adipose triglyceride lipase (ATGL). Upon lipolytic stimulation, PLIN1 is phosphorylated, releasing CGI-58 to fully activate ATGL and initiate triglyceride breakdown. The absence of PLIN1 in skeletal muscle leads us to believe that other PLIN family members undertake this role. Our purpose was to examine interactions between PLIN2, PLIN3, and PLIN5, with ATGL and its coactivator CGI-58 at rest and following contraction. Isolated rat solei were incubated for 30 min at rest or during 30 min of intermittent tetanic stimulation [150-ms volleys at 60 Hz with a train rate of 20 tetani/min (25°C)] to maximally stimulate intramuscular lipid breakdown. Results show that the interaction between ATGL and CGI-58 increased 128% following contraction (P = 0.041). Further, ATGL interacts with PLIN2, PLIN3, and PLIN5 at rest and following contraction. The PLIN2-ATGL interaction decreased significantly by 21% following stimulation (P = 0.013). Both PLIN3 and PLIN5 coprecipitated with CGI-58 at rest and following contraction, while there was no detectable interaction between PLIN2 and CGI-58 in either condition. Therefore, our findings indicate that in skeletal muscle, during contraction-induced muscle lipolysis, ATGL and CGI-58 strongly associate and that the PLIN proteins work together to regulate lipolysis, in part, by preventing ATGL and CGI-58 interactions at rest. PMID:23408028

  18. Validation of a Clinical Global Impression Scale for Aggression (CGI-A) in a sample of 558 psychiatric patients.

    PubMed

    Huber, Christian G; Lambert, Martin; Naber, Dieter; Schacht, Alexander; Hundemer, Hans-Peter; Wagner, Thomas T; Schimmelmann, Benno G

    2008-03-01

    Clinical management of aggression depends on the availability of easily administrable measurements allowing reliable evaluation. The present study's aim is to validate a Clinical Global Impression-Severity of Aggression scale (CGI-A). 558 inpatients with psychiatric disorders and an agitated-aggressive syndrome at baseline were continuously assessed over 5 days using CGI-A and the Positive and Negative Syndrome Scale-Excited Component (PANSS-EC). Equipercentile linking, correlation analyses and linear regression were applied. Relationship between CGI-A and PANSS-EC total score was found to be linear. On a 5-level CGI-A scale, values of 1 to 5 points were found to correspond to PANSS-EC scores of 12.2, 16.7, 21.3, 25.8, and 30.4, respectively (average increase: 4.6). All findings remained stable when only data from patients with schizophrenia spectrum disorders were analyzed. The CGI-A is proposed as a quickly administrable scale for the assessment of patients' aggressiveness.

  19. Instructional Rounds in Action

    ERIC Educational Resources Information Center

    Roberts, John E.

    2012-01-01

    "Instructional Rounds in Action" is an invaluable guide for those involved in implementing instructional rounds as the foundation and framework for systemic improvement in schools. Over the past few years, districts across the United States, Canada, and Australia have begun implementing "instructional rounds," a set of ideas…

  20. Getting To "Got It!" Helping Mathematics Students Reach Deep Understanding. Newsletter

    ERIC Educational Resources Information Center

    Oakes, Abner; Star, Jon R.

    2008-01-01

    This newsletter summarizes an IES practice guide titled "Organizing Instruction and Study to Improve Student Learning," which aims to supplement and inform teachers' instincts and experiences by identifying research-based instructional strategies that teachers of all content areas can use to improve student learning. The practice guide makes seven…

  1. Using a Combined Approach of Guided Inquiry & Direct Instruction to Explore How Physiology Affects Behavior

    ERIC Educational Resources Information Center

    Machtinger, Erika T.

    2014-01-01

    Hands-on activities with live organisms allow students to actively explore scientific investigation. Here, I present activities that combine guided inquiry with direct instruction and relate how nutrition affects the physiology and behavior of the common housefly. These experiments encourage student involvement in the formulation of experimental…

  2. Minds-On Audio-Guided Activities (MAGA): More than Hearing and Better than Seeing

    ERIC Educational Resources Information Center

    Hancock, James Brian, II; Fornari, Marco

    2012-01-01

    Minds-On Audio-Guided Activities (MAGA) are podcast-delivered instruction designed to facilitate learning through all-body experiments. Instruction by MAGA has undergone preliminary testing in an introductory physics course at Central Michigan University. Topics are currently focused on mechanics and range from discovering the differences between…

  3. Career Pathways Skill-Building Activities Guide.

    ERIC Educational Resources Information Center

    Community Coll. of Rhode Island, Warwick.

    In an effort to relate academic skills with workplace skills and facilitate the transition from school to work, the Community College of Rhode Island developed a skill-based instructional model targeted at 9th through 12th graders and consisting of 6 instructional areas, or strands, and 31 related skills. This guide provides suggested activities…

  4. A Model for Infusing Energy Concepts into Vocational Education Programs. Solar Energy Curriculum Guide.

    ERIC Educational Resources Information Center

    Delta Vocational Technical School, Marked Tree, AR.

    This solar energy curriculum guide is designed to assist teachers in infusing energy concepts into vocational education programs. It consists of 31 competency-based instructional units organized into 10 sections. Covered in the sections are the following topics: related instructions (history and development; human relations; general safety;…

  5. Industrial Electricity: Motors. Oklahoma Trade and Industrial Education.

    ERIC Educational Resources Information Center

    Teague, Cash; Pewewardy, Garner

    This curriculum guide provides competency-based instructional materials for training in the field of industrial electricity. Materials are not geared to a specific grade level and may be used with secondary and postsecondary students as well as part- and full-time adult students. The guide includes three sections and ten instructional units. Each…

  6. Food Science and Technology. Teacher's Instructional Guide [and] Reference Book.

    ERIC Educational Resources Information Center

    Texas Tech Univ., Lubbock. Curriculum Center for Family and Consumer Sciences.

    This reference book and teacher's instructional guide are intended for use in one- and two-year food science and technology programs for Texas high school students. The reference book provides information needed by employees in the food science and technology occupational area. Each chapter includes the following components: (1) a list of the…

  7. Tic Tac Toe Math. Instructional Guide.

    ERIC Educational Resources Information Center

    Cooper, Richard

    This instructional guide and set of three companion workbooks are intended for use in an arithmetic course based on the Tic Tac Toe method of addition and multiplication, which is an alternative means of learning to add and multiply that was developed for students whose learning disabilities (including difficulty in distinguishing left from right…

  8. Vocational Curriculum Resources for Disadvantaged Students. A Guide to Print and Non-Print Instructional Materials. Volume I.

    ERIC Educational Resources Information Center

    Mangano, R. Michael; And Others

    Volume 1 of a three-volume guide to vocational curriculum resources for disadvantaged students consists of instructional checklists for resources identified in the following areas: agriculture, auto body repair, automobile mechanics, basic math skills, basic reading skills, business education, carpentry, cosmetology, custodial and maintenance,…

  9. [A List of Curriculum Guides, Course Outlines, and Instructional Materials for All Areas of Vocational Education.

    ERIC Educational Resources Information Center

    The bibliography provides listings of currently available curriculum guides, course outlines, instructional and reference materials, and visual aids relevant to all areas of vocational education. The major areas under which listings are grouped include business and office occupations, trade and technical vocations, health education and…

  10. Vocational Agriculture 4. A Curriculum Guide. 12th Grade. Revised.

    ERIC Educational Resources Information Center

    Reeder, Dean

    The curriculum guide for Vocational Agriculture 4 (Grade 12) contains 27 color-coded units of instruction organized into four sections: farm business management, leadership and careers, plant and soil science, and agricultural mechanics. The instructional units are designed to account for 60% of an instructor's time, the remaining 40% is left to…

  11. Reference Guide for Teaching Selected Duty Areas from Business, Marketing and Management Occupations.

    ERIC Educational Resources Information Center

    Rich, John H.

    This reference guide was designed to assist business, marketing, and management educators in locating textbook/instructional materials for use in teaching duty areas and task lists for grades 11-14. Duty areas and task lists are matched with selected textbook/instructional publications for the secretarial, general office clerk, and information…

  12. INSTRUCTIONAL GUIDE FOR THE TEACHING OF HEALTH AND PHYSICAL EDUCATION. PRIMARY THROUGH SENIOR HIGH SCHOOL.

    ERIC Educational Resources Information Center

    BROCKMEYER, W.

    AN INSTRUCTIONAL GUIDE FOR THE TEACHING OF HEALTH AND PHYSICAL EDUCATION, EMPHASIZING EDUCATION BY EXPERIENCE IN ACTIVITY, WAS PRESENTED. THE GOALS WERE TO DEVELOP GOOD HUMAN RELATIONSHIPS, GOOD SELF-REALIZATION, CIVIC RESPONSIBILITY, AND ECONOMIC EFFICIENCY. THE PROGRAM FOR BOYS, GRADES SEVEN THROUGH NINE, INCLUDED CALISTHENICS APPARATUS (SUCH AS…

  13. The Role of Guided Induction in Paper-Based Data-Driven Learning

    ERIC Educational Resources Information Center

    Smart, Jonathan

    2014-01-01

    This study examines the role of guided induction as an instructional approach in paper-based data-driven learning (DDL) in the context of an ESL grammar course during an intensive English program at an American public university. Specifically, it examines whether corpus-informed grammar instruction is more effective through inductive, data-driven…

  14. Estimation of Food Guide Pyramid Serving Sizes by College Students.

    ERIC Educational Resources Information Center

    Knaust, Gretchen; Foster, Irene M.

    2000-01-01

    College students (n=158) used the Food Guide Pyramid to select serving sizes on a questionnaire (73% had been instructed in its use). Overall mean scores (31% correct) indicated they generally did not know recommended serving sizes. Those who had read about or received instruction in the pyramid had higher mean scores. (SK)

  15. A Guide to Courseware Authoring Options in ESL/FL Instruction.

    ERIC Educational Resources Information Center

    Hampson, S. L.

    A guide to courseware authoring aids for computer-assisted language instruction (CALIS) gives suggestions for the selection and use of programing options and provides an annotated listing of those options. Introductory sections discuss the use of computer-assisted language teaching, the selection of quality courseware, the types of authoring aids…

  16. Social Science Instructional Guides: High School (Grades 9-12).

    ERIC Educational Resources Information Center

    Hartman, Carl; And Others

    The guide, part of a social science learning continuum from first through twelfth grades, contains outlines for two-semester social studies courses for grades 9-12. Three components comprise each section: time allocations for units, instructional objectives, and a content outline. The Grade 9 course, Cultures of the Non-Western World, contains…

  17. Competency Based Instructional Resource Guide. Sample Format. Welding.

    ERIC Educational Resources Information Center

    Hoerner, James L.; Horne, Ralph A.

    The purpose of this sample guide is to assist teachers and curriculum specialists in developing instructional materials that are competency based and that meet Virginia standards for competency-based education (CBE) programs. The sample deals with the occupation of welding, but it is the format that is of interest here, not the subject matter.…

  18. Colorado State Plan for the Developmentally Disabled: Master Planning Guide for Instructional Objectives. Second Edition.

    ERIC Educational Resources Information Center

    Shibata, Paul

    A product of joint effort between the Colorado Department of Institutions and the Division of Developmental Disabilities, the guide presents hierarchically arranged instructional objectives to determine goals for developmentally disabled persons. The most advanced skills are listed first with basic skills following for four major categories:…

  19. Using Literature-Based Prompts To Teach Writing Competencies: Directed Reading and Writing Lessons.

    ERIC Educational Resources Information Center

    Gelsinger, Barry D.

    Intended to help teachers integrate writing instruction with the study of literature, this teaching guide offers a philosophy of writing instruction, describes a procedure for teaching reading and writing lessons, and provides a sequence of writing skills. For various literature selections, the guide defines vocabulary, provides topic discussion…

  20. Guide to Effective Business Practices in Buying School Supplies, Instructional Materials, Equipment and Services.

    ERIC Educational Resources Information Center

    Association of School Business Officials International, Reston, VA.

    This guide to effective business practices is intended to assist schools in establishing general policies and procedures for buying supplies, instructional materials, equipment, and services. Federal, state, and local laws must be considered in addition to the recommendations made in this report. Practical guidelines are given for selecting…

  1. Consumer and Family Economics: Teacher's Instructional Guide.

    ERIC Educational Resources Information Center

    Dennis, Bobbye

    This teacher's instructional guide, which is part of a family and consumer sciences education series focusing on a broad range of employment opportunities, is intended to assist teachers responsible for teaching one- and two-year consumer and family economics programs for Texas high school students. The following are among the items included: (1)…

  2. Creativity: A Saleable Work Skill. Occupation Simulation Packet. Grades 3rd-4th.

    ERIC Educational Resources Information Center

    Dye, Dick

    This teacher's guide for grades 3 and 4 contains simulated work experiences for students using the isolated skill concept - creativity. Teacher instructions include objectives, evaluation, and sequence of activities. The guide contains pre-tests and post-tests with instructions and answer keys. Two pre-skill activities are suggested, such as…

  3. Benefits of Guided Self-Management of Attention on Learning Accounting

    ERIC Educational Resources Information Center

    Sithole, Seedwell T. M.; Chandler, Paul; Abeysekera, Indra; Paas, Fred

    2017-01-01

    This research investigated the effects of 3 instructional design formats on learning introductory accounting. In accordance with cognitive load theory, it was predicted that students who would learn with a guided self-managed instructional design format would outperform students who would learn with a conventional split-attention format or an…

  4. Agribusiness Management and Operation. Instructional Materials Developed for Iowa Agricultural Science, Technology and Marketing Teachers.

    ERIC Educational Resources Information Center

    Iowa State Univ. of Science and Technology, Ames. Dept. of Agricultural Education.

    This curriculum guide can be used by secondary and postsecondary agriculture, technology, and marketing instructors to decide what and how to teach about agricultural business organization and management, especially in Iowa. The guide consists of five instructional units: (1) agribusiness organization and management; (2) livestock sales and…

  5. The Influence of Guided Error-Based Learning on Motor Skills Self-Efficacy and Achievement.

    PubMed

    Chien, Kuei-Pin; Chen, Sufen

    2018-01-01

    The authors investigated the role of errors in motor skills teaching, specifically the influence of errors on skills self-efficacy and achievement. The participants were 75 undergraduate students enrolled in pétanque courses. The experimental group (guided error-based learning, n = 37) received a 6-week period of instruction based on the students' errors, whereas the control group (correct motion instruction, n = 38) received a 6-week period of instruction emphasizing correct motor skills. The experimental group had significantly higher scores in motor skills self-efficacy and outcomes than did the control group. Novices' errors reflect their schema in motor skills learning, which provides a basis for instructors to implement student-centered instruction and to facilitate the learning process. Guided error-based learning can effectively enhance beginners' skills self-efficacy and achievement in precision sports such as pétanque.

  6. Use of Image-Guided Stereotactic Body Radiation Therapy in Lieu of Intracavitary Brachytherapy for the Treatment of Inoperable Endometrial Neoplasia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kemmerer, Eric; Hernandez, Enrique; Ferriss, James S.

    2013-01-01

    Purpose: Retrospective analysis of patients with invasive endometrial neoplasia who were treated with external beam radiation therapy followed by stereotactic body radiation therapy (SBRT) boost because of the inability to undergo surgery or brachytherapy. Methods and Materials: We identified 11 women with stage I-III endometrial cancer with a median age of 78 years that were not candidates for hysterectomy or intracavitary brachytherapy secondary to comorbidities (91%) or refusal (9%). Eight patients were American Joint Committee on Cancer (AJCC) stage I (3 stage IA, 5 stage IB), and 3 patients were AJCC stage III. Patients were treated to a median ofmore » 4500 cGy at 180 cGy per fraction followed by SBRT boost (600 cGy per fraction Multiplication-Sign 5). Results: The most common side effect was acute grade 1 gastrointestinal toxicity in 73% of patients, with no late toxicities observed. With a median follow-up of 10 months since SBRT, 5 patients (45%) experienced locoregional disease progression, with 3 patients (27%) succumbing to their malignancy. At 12 and 18 months from SBRT, the overall freedom from progression was 68% and 41%, respectively. Overall freedom from progression (FFP) was 100% for all patients with AJCC stage IA endometrial carcinoma, whereas it was 33% for stage IB at 18 months. The overall FFP was 100% for International Federation of Obstetrics and Gynecology grade 1 disease. The estimated overall survival was 57% at 18 months from diagnosis. Conclusion: In this study, SBRT boost to the intact uterus was feasible, with encouragingly low rates of acute and late toxicity, and favorable disease control in patients with early-stage disease. Additional studies are needed to provide better insight into the best management of these clinically challenging cases.« less

  7. Instructed Pragmatics at a Glance: Where Instructional Studies Were, Are, and Should Be Going

    ERIC Educational Resources Information Center

    Taguchi, Naoko

    2015-01-01

    This paper brings together the research and developments of instructed pragmatics over the past three decades by reporting the synthesis findings of instructional intervention studies in interlanguage pragmatics. Two questions have guided this investigation: (1) is instruction effective in learning pragmatics?; and (2) what methods are most…

  8. Volleyball: Special Olympics Sports Skills Instructional Program.

    ERIC Educational Resources Information Center

    Special Olympics, Inc., Washington, DC.

    One of seven booklets on Special Olympics Sports Skills Instructional Programs, this guide presents an instructional program for volleyball coaches working with mentally retarded persons. The instructional program presents information on the following topics: long term goals; short term objectives; modifications and adaptations of equipment, sport…

  9. TU-AB-BRA-11: Indications for Online Adaptive Radiotherapy Based On Dosimetric Consequences of Interfractional Pancreas-To-Duodenum Motion in MRI-Guided Pancreatic Radiotherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mittauer, K; Rosenberg, S; Geurts, M

    Purpose: Dose limiting structures, such as the duodenum, render the treatment of pancreatic cancer challenging. In this multi-institutional study, we assess dosimetric differences caused by interfraction pancreas-to-duodenum motion using MR-IGRT to determine the potential impact of adaptive replanning. Methods: Ten patients from two institutions undergoing MRI-guided radiotherapy with conventional fractionation (n=5) or SBRT (n=5) for pancreatic cancer were included. Initial plans were limited by duodenal dose constraints of 50 Gy (0.5 cc)/31 Gy (0.1 cc) for conventional/SBRT with prescriptions of 30 Gy/5 fractions (SBRT) and 40–50 Gy/25 fractions (conventional). Daily volumetric MR images were acquired under treatment conditions on amore » clinical MR-IGRT system. The correlation was assessed between interfractional GTV-to-duodenum positional variation and daily recalculations of duodenal dose metrics. Positional variation was quantified as the interfraction difference in Hausdorff distance from simulation baseline (ΔHD) between the GTV and proximal duodenal surface, or volume overlap between GTV and duodenum for cases with HD{sub 0}=0 (GTV abutting duodenum). Adaptation was considered indicated when daily positional variations enabled dose escalation to the target while maintaining duodenal constraints. Results: For fractions with ΔHD>0 (n=14, SBRT only), the mean interfraction duodenum dose decrease from simulation to treatment was 44±53 cGy (maximum 136 cGy). A correlation was found between ΔHD and dosimetric difference (R{sup 2}=0.82). No correlation was found between volume of overlap and dosimetric difference (R{sup 2}=0.31). For 89% of fractions, the duodenum remained overlapped with the target and the duodenal dose difference was negligible. The maximum observed indication for adaptation was for interfraction ΔHD=11.6 mm with potential for adaptive dose escalation of 136 cGy. Conclusion: This assessment showed that Hausdorff distance was a reasonable metric to use to determine the indication for adaptation. Adaptation was potentially indicated in 11% of the treatments (fractions where GTV-to-duodenum distance increased from simulation), with a feasible average dose escalation of 7.0%. MB, LH, JO, RK, PP: research and/or travel funding from ViewRay Inc. PP: research grant from Varian Medical Systems and Philips Healthcare.« less

  10. Design and assessment of an interactive physics tutoring environment

    NASA Astrophysics Data System (ADS)

    Scott, Lisa Ann

    2001-07-01

    The application of scientific principles is an extremely important skill taught in undergraduate introductory science courses, yet many students emerge from such courses unable to reliably apply the scientific principles they have ostensibly learned. In an attempt to address this problem, the knowledge and thought processes needed to apply an important principle in introductory physics (Newton's law) were carefully analyzed. Reliable performance requires not only declarative knowledge but also corresponding procedural knowledge and the basic cognitive functions of deciding, implementing and assessing. Computer programs called guided-practice PALs (P&barbelow;ersonal A&barbelow;ssistants for Ḻearning) were developed to teach explicitly the knowledge and thought processes needed to apply Newton's law to solve problems. These programs employ a modified form of Palincsar and Brown's reciprocal-teaching strategy (1984) in which students and computers alternately coach each other, taking turns making decisions, implementing and assessing them. The computer programs make it practically feasible to provide students with individual guidance and feedback ordinarily unavailable in most courses. In a pilot study, the guided-practice PALs were found to be nearly as effective as individual tutoring by expert teachers and significantly more effective than the instruction provided in a well-taught physics course. This guided practice however is not sufficient to ensure that students develop the ability to perform independently. Accordingly, independent-performance PALs were developed which require students to work independently, receiving only the minimal feedback necessary to successfully complete the task. These independent-performance PALS are interspersed with guided-practice PALs to create an instructional environment which facilitates a gradual transition to independent performance. In a study designed to assess the efficacy of the PAL instruction, students in the PAL group used only guided-practice PALS and students in the PAL+ group used both guided-practice and independent-performance PALS. The performance of the PAL and PAL+ groups were compared to the performance of a Control group which received traditional instruction. The addition of the independent-performance PALS proved to be at least as effective as the guided-practice PALs alone, and both forms of PAL instruction were significantly more effective than traditional instruction.

  11. Dosimetric Evaluation Between Megavoltage Cone-Beam Computed Tomography and Body Mass Index for Intracranial, Thoracic, and Pelvic Localization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    VanAntwerp, April E.; Raymond, Sarah M., E-mail: raymons9@ccf.org; Addington, Mark C.

    2011-10-01

    The aim of this study was to evaluate radiation dose for organs at risk (OAR) within the cranium, thorax, and pelvis from megavoltage cone-beam computed tomography (MV-CBCT). Using a clinical treatment planning system, CBCT doses were calculated from 60 patient datasets using 27.4 x 27.4 cm{sup 2} field size and 200{sup o} arc length. The body mass indices (BMIs) for these patients range from 17.2-48.4 kg/m{sup 2}. A total of 60 CBCT plans were created and calculated with heterogeneity corrections, with monitor units (MU) that varied from 8, 4, and 2 MU per plan. The isocenters of these plans weremore » placed at defined anatomical structures. The maximum dose, dose to the isocenter, and mean dose to the selected critical organs were analyzed. The study found that maximum and isocenter doses were weakly associated with BMI, but linearly associated with the total MU. Average maximum/isocenter doses in the cranium were 10.0 ({+-} 0.18)/7.0 ({+-} 0.08) cGy, 5.0 ({+-} 0.09)/3.5 ({+-} 0.05) cGy, and 2.5 ({+-} .04)/1.8 ({+-} 0.05) cGy for 8, 4, and 2 MU, respectively. Similar trends but slightly larger maximum/isocenter doses were found in the thoracic and pelvic regions. For the cranial region, the average mean doses with a total of 8 MU to the eye, lens, and brain were 9.7 ({+-} 0.12) cGy, 9.1 ({+-} 0.16) cGy, and 7.2 ({+-} 0.10) cGy, respectively. For the thoracic region, the average mean doses to the lung, heart, and spinal cord were 6.6 ({+-} 0.05) cGy, 6.9 ({+-} 1.2) cGy, and 4.7 ({+-} 0.8) cGy, respectively. For the pelvic region, the average mean dose to the femoral heads was 6.4 ({+-} 1.1) cGy. The MV-CBCT doses were linearly associated with the total MU but weakly dependent on patients' BMIs. Daily MV-CBCT has a cumulative effect on the total body dose and critical organs, which should be carefully considered for clinical impacts.« less

  12. Differentiating Writing Instruction: Meeting the Diverse Needs of Authors in a Classroom

    ERIC Educational Resources Information Center

    Shea, Mary

    2015-01-01

    This article outlines a rational for responsive, differentiated writing instruction that targets students' identified needs with respect to various dimensions of the writing process. Discussed is a cycle that requires ongoing assessment, instructional decision-making, responsive, differentiated instruction, guided practice, and assessment.…

  13. PDQ: Planning and Development of Quality Services in the Schools, Instructional Guide, Student Manual and Reference Materials.

    ERIC Educational Resources Information Center

    Wright, Sandra Raymore

    The instructional guide, student manual, and reference materials were developed by the PDQ Project, Planning and Development of Quality Services in the Schools, an effort by the American Speech-Language-Hearing Association to provide public school personnel working with communication disordered children with information and training related to…

  14. OUR's: Optimum Utilization of Resources; A Guide to Instructional Resources in Occupational Education. Research Pub. 77-1.

    ERIC Educational Resources Information Center

    Beamish, Eric; And Others

    This resource guide contains over 300 entries which are available through the Optimum Utilization of Resources (OUR's) exchange system. The entries describe learning materials, such as slides, video tapes, audio tapes, films, print material, and computer assisted instructional programs, which have been developed primarily by faculty of the…

  15. Social Studies: 1970; Instructional Objectives for Grades 1-8.

    ERIC Educational Resources Information Center

    Catholic School Board, Chicago, IL.

    The objectives of this curriculum guide for teachers are: 1) to provide a unified list of yearly instructional objectives for each social studies classroom; 2) to provide basic standards for measuring pupil progress; and 3) to provide a guide for the continuous development in the social studies. The recommendations for each grade level cover:…

  16. Does Staff Development in Cognitively Guided Instructional Theory Change Middle School Teachers' Mental Models about Teaching and Learning?

    ERIC Educational Resources Information Center

    Schmitz, Judith R.

    This practicum was designed to increase middle-level teaching teams' understanding of cognitively guided instructional strategies or brain-based learning theories and to promote the incorporation of these strategies into the teaching of cross-curriculum thematic units. Twelve staff development modules based on a new perspective of learning which…

  17. Plant Operations for Wastewater Facilities, Vol. II, Part D. An Instructor's Guide for Use of Instructional Material in Wastewater Technology Training Programs.

    ERIC Educational Resources Information Center

    Stoakes, K. C.; And Others

    This instructor's guide, designed for use with the curriculum, Plant Operations for Wastewater Facilities, represents a two-year wastewater technology instructional program based on performance objectives designed to prepare undergraduate students to enter occupations in water and wastewater treatment plant operations and maintenance. This…

  18. Health Occupations Education. Units of Instruction. Teacher's Guide. Volume II.

    ERIC Educational Resources Information Center

    Williams, Catherine

    This manual is the second part of a two-volume teacher's guide to a series of instructional units for use in health occupations education programs in Texas. Covered in the 10 units included in this volume are the following topics: special procedures (administering oxygen to patients; using elastic bandages; assisting with postural drainage; and…

  19. Improving Second Grade Student's Reading Fluency and Comprehension Using Teacher-Guided iPad® App Instruction

    ERIC Educational Resources Information Center

    Redcay, Jessica D.; Preston, Sean M.

    2016-01-01

    Purpose: This study aims to examine the differences in second grade students' reading fluency and comprehension scores when using varying levels of teacher-guided iPad® app instruction to determine effective reading practices. Design/methodology/approach: This study reports the results of the quasi-experimental pre-post study by providing…

  20. Using Evidence-Based Multimedia to Improve Vocabulary Performance of Adolescents With LD: A UDL Approach

    ERIC Educational Resources Information Center

    Kennedy, Michael J.; Thomas, Cathy Newman; Meyer, J. Patrick; Alves, Kat D.; Lloyd, John Wills

    2014-01-01

    Universal Design for Learning (UDL) is a framework that is commonly used for guiding the construction and delivery of instruction intended to support all students. In this study, we used a related model to guide creation of a multimedia-based instructional tool called content acquisition podcasts (CAPs). CAPs delivered vocabulary instruction…

  1. Plant Operations for Wastewater Facilities, Vol. II, Part E. An Instructor's Guide for Use of Instructional Material in Wastewater Technology Training Programs.

    ERIC Educational Resources Information Center

    Stoakes, K. C.; And Others

    This instructor's guide, designed for use with the curriculum, Plant Operations for Wastewater Facilities, represents a two-year wastewater technology instructional program based on performance objectives designed to prepare undergraduate students to enter occupations in water and wastewater treatment plant operations and maintenance. This…

  2. SCDC Spanish Curricula Units. Language Arts, Unit 6, Grade 2, Teacher's Guide.

    ERIC Educational Resources Information Center

    Spanish Curricula Development Center, Miami Beach, FL.

    Language arts instructional and assessment activities for grade two are described in this teacher's guide to the language arts strand of unit six. Focus, objective and materials for each activity are given in English and Spanish, with teacher instructions only in Spanish. This strand includes a continuation of the basic activities of past units:…

  3. Crawling and/or Squatting: A Saleable Work Skill. Occupation Simulation Packet. Grades K-2nd.

    ERIC Educational Resources Information Center

    Montgomery, Margery

    This teacher's guide for grades K-2 contains simulated work experiences for students using the isolated skill concept, crawling and/or squatting. Teacher instructions include objectives, evaluation, and sequence of activities. The guide contains pre-tests and post-tests with instructions and answer keys. Three pre-skill activities are suggested,…

  4. Alcohol and Drug Abuse Curriculum Guide for Psychiatry Faculty. Medicine 2. Health Professions Education Curriculum Resource Series.

    ERIC Educational Resources Information Center

    Gallant, Donald S.

    This guide, one of a series of publications written for medical school faculty to use in designing substance abuse instruction, focuses on curriculum content for drug and alcohol abuse instruction. Following a brief introduction, discussions of positive attitude development toward substance abuse patients, and the psychological, cultural, and…

  5. Instructional Television Facilities: A Guide for School Administrators and Board Members. PREP-1.

    ERIC Educational Resources Information Center

    Oberholtzer, Kenneth E.

    The purpose of this Guide, for school administrators and board members, is to provide newcomers in television with an understanding of Instructional Television (ITV) facilities for school and school systems. The discussions herein provide the reader with information and direction to enable him to select the best facilities for his purposes. For…

  6. An Instructional System in Physical Science, Teacher's Guide and Keys.

    ERIC Educational Resources Information Center

    Washington State Univ., Pullman.

    This manual is a teacher's guide to a self-instructional program in basic physical science, designed for high school students who have not had a course in chemistry or physics. There are six units in the manual relating to these areas: problem solving and experimental procedures; universal standards, metric system and conversion; mechanics; the…

  7. Plant Operations for Wastewater Facilities, Vol. II, Part B. An Instructor's Guide for Use of Instructional Material in Wastewater Technology Training Programs.

    ERIC Educational Resources Information Center

    Stoakes, K. C.; And Others

    This instructor's guide, designed for use with the curriculum, Plant Operations for Wastewater Facilities, represents a two-year wastewater technology instructional program based on performance objectives designed to prepare undergraduate students to enter occupations in water and wastewater treatment plant operations and maintenance. This…

  8. Plant Operations for Wastewater Facilities, Vol. II, Part A. An Instructor's Guide for Use of Instructional Material in Wastewater Technology Training Programs.

    ERIC Educational Resources Information Center

    Stoakes, K. C.; And Others

    This instructor's guide, designed for use with the curriculum, Plant Operations for Wastewater Facilities, represents a two-year wastewater technology instructional program based on performance objectives designed to prepare undergraduate students to enter occupations in water and wastewater treatment plant operations and maintenance. This…

  9. Plant Operations for Wastewater Facilities, Vol. II, Part C. An Instructor's Guide for Use of Instructional Material in Wastewater Technology Training Programs.

    ERIC Educational Resources Information Center

    Stoakes, K. C.; And Others

    This instructor's guide, designed for use with the curriculum, Plant Operations for Wastewater Facilities, represents a two-year wastewater technology instructional program based on performance objectives designed to prepare undergraduate students to enter occupations in water and wastewater treatment plant operations and maintenance. This…

  10. Military Curriculum Materials for Vocational and Technical Education. Diet Therapy Specialist, 9-6.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. National Center for Research in Vocational Education.

    This plan of instruction, teaching guide, and student study guides/workbooks for a secondary-postsecondary level course for diet therapy specialists comprise one of a number of military-developed curriculum packages selected for adaptation to vocational instruction and curriculum development in a civilian setting. Purpose of the 114-hour course is…

  11. Does a Repeated Guided-Instruction Approach with Multiple Assessments Increase Student Learning of Science?

    ERIC Educational Resources Information Center

    Smith, Robert; Peethambaran, Bela; Pontiggia, Laura; Blumberg, Phyllis

    2013-01-01

    Guided instruction is an approach that fully explains the concepts and procedures that students are required to learn. It seems intuitive that this approach should increase student learning; however, there is evidence in the literature that this may not always be the case. We wanted to assess the effectiveness of our own repeated…

  12. Composing as the Curriculum: A Guide for Instruction in Written Composition, Grades K-12.

    ERIC Educational Resources Information Center

    Blake, Robert W.; Tuttle, Frederick B., Jr.

    The Albion (New York) school district provides this guide to written composition instruction in its kindergarten through grade 12 curriculum because of the importance and necessity of writing, not only as a school activity but also as a lifelong intellectual, self-actualizing, and daily-living activity. Following a brief overview that summarizes…

  13. The Effect of Guided Inquiry-Based Instruction on Middle School Students' Understanding of Lunar Concepts

    ERIC Educational Resources Information Center

    Trundle, Kathy Cabe; Atwood, Ronald K.; Christopher, John E.; Sackes, Mesut

    2010-01-01

    This study investigated the effect of non-traditional guided inquiry instruction on middle school students' conceptual understandings of lunar concepts. Multiple data sources were used to describe participants' conceptions of lunar phases and their cause, including drawings, interviews, and a lunar shapes card sort. The data were analyzed via a…

  14. Assembling in Sequence: A Saleable Work Skill. Occupation Simulation Packet. Grades 3rd-4th.

    ERIC Educational Resources Information Center

    Hueston, Jean

    This teacher's guide for grades 3 and 4 contains simulated work experiences for students using the isolated skill concept - assembling in sequence. Teacher instructions include objectives, evaluation, and sequence of activities. The guide contains pre-tests and post-tests with instructions and answer keys. Three pre-skill activities are suggested,…

  15. Oral Persuasion: A Saleable Work Skill. Occupation Simulation Packet. Grades 5th-6th.

    ERIC Educational Resources Information Center

    Lee, Dennis W.

    This teacher's guide contains simulated work experiences for 5th and 6th grade students using the isolated skill concept - oral persuasion. Teacher instructions include objectives, evaluation, and sequence of activities. The guide contains pre-tests and post-tests with instructions and answer keys. Two pre-skill activities are suggested, such as…

  16. Advanced Marketing. Marketing Education Teacher's Resource Guide. Expected Student Learning Outcomes and Cross-Referenced Instructional Materials by Competencies.

    ERIC Educational Resources Information Center

    Smith, Clifton L.

    This guide, developed by a project to revise the minimum core competencies for the advanced marketing course in secondary marketing education in Missouri, contains four sections. The first section explains competency-based marketing education, including its mission, nature, curriculum, and the fundamentals of competency-based instruction. The…

  17. Fundamentals of Marketing. Marketing Education Teacher's Resource Guide. Expected Student Learning Outcomes and Cross-Referenced Instructional Materials by Competencies.

    ERIC Educational Resources Information Center

    Smith, Clifton L.

    This guide, developed by a project to revise the minimum core competencies for the Fundamentals of Marketing course in secondary marketing education in Missouri, contains four sections. The first section explains competency-based marketing education, including its mission, nature, curriculum, and the fundamentals of competency-based instruction.…

  18. COATING ALTERNATIVES GUIDE (CAGE) USER'S GUIDE

    EPA Science Inventory

    The guide provides instructions for using the Coating Alternatives GuidE (CAGE) software program, version 1.0. It assumes that the user is familiar with the fundamentals of operating an IBM-compatible personal computer (PC) under the Microsoft disk operating system (MS-DOS). CAGE...

  19. SAGE 2.1: SOLVENT ALTERNATIVES GUIDE: USER'S GUIDE

    EPA Science Inventory

    The guide provides instruction for using the SAGE (Solvent Alternatives GuidE) software system, version 2.1. SAGE recommends solvent replacements in cleaning and degreasing operations. It leads the user through a question-and-answer session. The user's responses allow the system ...

  20. Technical Evaluation for the Determination of CGI Designation for Safety Class Items Incorporated in Hose-in-Hose Transfer Line Assemblies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    BUCHANAN, J.R.

    2000-05-16

    The purpose of this technical evaluation is to determine whether the secondary hoses are to be categorized as Commercial Grade Items (CGI) or Engineered Equipment. This determination will identify whether or not use of the CGI Dedication process is appropriate.

  1. Disruption of the Arabidopsis CGI-58 homologue produces Chanarin-Dorfman-like lipodystrophy in plants

    USDA-ARS?s Scientific Manuscript database

    CGI-58 is the defective gene in the human neutral lipid storage disease called Chanarin-Dorfman syndrome. This disorder causes intracellular lipid droplets to accumulate in nonadipose tissues, such as skin and blood cells. Here, disruption of the homologous CGI-58 gene in Arabidopsis thaliana result...

  2. Successful pregnancy following very high-dose total body irradiation (1575 cGy) and bone marrow transplantation in a woman with acute myeloid leukemia.

    PubMed

    Wang, W S; Tzeng, C H; Hsieh, R K; Chiou, T J; Liu, J H; Yen, C C; Chen, P M

    1998-02-01

    A 22-year-old woman had a normal full-term delivery 6 years after a successful allogeneic bone marrow transplantation (BMT) for acute myeloid leukemia (AML). Conditioning therapy consisted of cyclophosphamide (120 mg/kg) and total body irradiation (TBI) to a total of 1575 cGy in seven fractions (225 cGy x 7, at a dose rate of 3.5 cGy/min). Graft-versus-host disease prophylaxis was with methotrexate and cyclosporin A. Grade I acute GVHD developed after BMT but there was no chronic GVHD. She became amenorrhoeic after BMT and serial gonadal testing indicated hypergonadotrophic hypogonadism. She became pregnant and delivered a full-term, healthy baby 6 years after BMT. Successful pregnancy after TBI of more than 1200 cGy is extremely rare. This case, to the best of our knowledge, is the second patient who received a higher dose of TBI (1575 cGy) to have a successful pregnancy. This and previous reports indicate that normal pregnancy is possible after BMT with TBI in excess of 1200 cGy.

  3. Marrow toxicity of fractionated vs. single dose total body irradiation is identical in a canine model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Storb, R.; Raff, R.F.; Graham, T.

    1993-03-20

    The authors explored in dogs the marrow toxicity of single dose total body irradiation delivered from two opposing [sup 60]Co sources at a rate of 10 cGy/min and compared results to those seen with total body irradiation administered in 100 cGy fractions with minimum interfraction intervals of 6 hr. Dogs were not given marrow transplants. They found that 200 cGy single dose total body irradiation was sublethal, with 12 of 13 dogs showing hematopoietic recovery and survival. Seven of 21 dogs given 300 cGy single dose total body irradiation survived compared to 6 of 10 dogs given 300 cGy fractionatedmore » total body irradiation. One of 28 dogs given 400 cGy single dose total body irradiation survived compared to none of six given fractionated radiation. With granulocyte colony stimulating factor (GCSF) administered from day 0-21 after 400 cGy total body irradiation, most dogs survived with hematological recovery. Because of the almost uniform success with GCSF after 400 cGy single dose total body irradiation, a study of GCSF after 400 cGy fractionated total body irradiation was deemed not to be informative and, thus, not carried out. Additional comparisons between single dose and fractionated total body irradiation were carried out with GCSF administered after 500 and 600 cGy of total body irradiation. As with lower doses of total body irradiation, no significant survival differences were seen between the two modes of total body irradiation, and only 3 of 26 dogs studied survived with complete hematological recovery. Overall, therefore, survival among dogs given single dose total body irradiation was not different from that of dogs given fractionated total body irradiation (p = .67). Similarly, the slopes of the postirradiation declines of granulocyte and platelet counts and the rates of their recovery in surviving dogs given equal total doses of single versus fractionated total body irradiation were indistinguishable. 24 refs., 3 figs., 2 tabs.« less

  4. Instructional Environments for Learners Having Severe Handicaps.

    ERIC Educational Resources Information Center

    Baine, David, Ed.

    This collection of papers examines instructional environments for students with severe disabilities. It points out that two principles should guide the selection of all instructional environments for all types of learners at all stages of instruction: the environment should be the least restrictive environment possible and it should be the most…

  5. Automotive Electricity: Automotive Mechanics Instructional Program. Block 3.

    ERIC Educational Resources Information Center

    O'Brien, Ralph D.

    The third of six instructional blocks in automotive mechanics, the lessons and supportive information in the document provide a guide for teachers in planning an instructional program in automotive electricity at the secondary and post secondary level. The material, as organized, is a suggested sequence of instruction within each block. Each…

  6. Engine Fundamentals: Automotive Mechanics Instructional Program. Block 2.

    ERIC Educational Resources Information Center

    O'Brien, Ralph D.

    The second of six instructional blocks in automotive mechanics, the lessons and supportive information in the document provide a guide for teachers in planning an instructional program in engine fundamentals at the secondary and postsecondary level. The material, as organized, is a suggested sequence of instruction within each block. Each lesson…

  7. An Instructional Media Selection Guide for Distance Learning. Fourth Edition

    ERIC Educational Resources Information Center

    Holden, Jolly T.; Westfall, Philip J.-L.

    2007-01-01

    Increasingly, educators and trainers are challenged within their respective organizations to provide for the efficient distribution of instructional content using instructional media. The appropriate selection of instructional media to support distance learning is not intuitive and does not occur as a matter of personal preference. On the…

  8. Practically Speaking: A Sourcebook for Instructional Consultants in Higher Education.

    ERIC Educational Resources Information Center

    Brinko, Kathleen T., Ed.; Menges, Robert J., Ed.

    The selections in this sourcebook offer a blend of research-based principles and practical advice to the instructional consultant. The first section, Skills and Techniques of Instructional Consultation, contains: (1) The Interactions of Teaching Improvement (Kathleen T. Brink); (2) Instructional Consulting: A Guide for Developing Professional…

  9. Effects of aripiprazole once-monthly on symptoms of schizophrenia in patients switched from oral antipsychotics.

    PubMed

    Peters-Strickland, Timothy; Zhao, Cathy; Perry, Pamela P; Eramo, Anna; Salzman, Phyllis M; McQuade, Robert D; Johnson, Brian R; Sanchez, Raymond

    2016-12-01

    To assess the effects of aripiprazole once-monthly 400 mg (AOM 400) on clinical symptoms and global improvement in schizophrenia after switching from an oral antipsychotic. In a multicenter, open-label, mirror-image, naturalistic study in patients with schizophrenia (>1 year, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision [DSM-IV-TR] criteria), changes in efficacy measures were assessed during prospective treatment (6 months) with AOM 400 after switching from standard-of-care oral antipsychotics. During prospective treatment, patients were cross-titrated to oral aripiprazole monotherapy (1-4) weeks followed by open-label AOM 400 (24 weeks). Mean change from baseline of the open-label AOM 400 phase in Positive and Negative Syndrome Scale (PANSS) scores (total, positive and negative subscales) and Clinical Global Impression-Severity (CGI-S) scores; mean CGI-Improvement (CGI-I) score; and proportion of responders (≥30% decrease from baseline in PANSS total score or CGI-I score of 1 [very much improved] or 2 [much improved]) were assessed. PANSS and CGI-S scores improved from baseline (P<0.0001) and CGI-I demonstrated improvement at all time points. By the end of the study, 49.0% of patients were PANSS or CGI-I responders. In a community setting, patients with schizophrenia who were stabilized at baseline and switched to AOM 400 from oral antipsychotics showed clear improvements in clinical symptoms.

  10. Quantitative profiling of CpG island methylation in human stool for colorectal cancer detection.

    PubMed

    Elliott, Giles O; Johnson, Ian T; Scarll, Jane; Dainty, Jack; Williams, Elizabeth A; Garg, D; Coupe, Amanda; Bradburn, David M; Mathers, John C; Belshaw, Nigel J

    2013-01-01

    The aims of this study were to investigate the use of quantitative CGI methylation data from stool DNA to classify colon cancer patients and to relate stool CGI methylation levels to those found in corresponding tissue samples. We applied a quantitative methylation-specific PCR assay to determine CGI methylation levels of six genes, previously shown to be aberrantly methylated during colorectal carcinogenesis. Assays were performed on DNA from biopsies of "normal" mucosa and stool samples from 57 patients classified as disease-free, adenoma, or cancer by endoscopy, and in tumour tissue from cancer patients. Additionally, CGI methylation was analysed in stool DNA from an asymptomatic population of individuals covering a broad age range (mean = 47 ± 24 years) CGI methylation levels in stool DNA were significantly higher than in DNA from macroscopically normal mucosa, and a significant correlation between stool and mucosa was observed for ESR1 only. Multivariate statistical analyses using the methylation levels of each CGI in stool DNA as a continuous variable revealed a highly significant (p = 0.003) classification of cancer vs. non-cancer (adenoma + disease-free) patients (sensitivity = 65 %, specificity = 81 %). CGI methylation profiling of stool DNA successfully identified patients with cancer despite the methylation status of CGIs in stool DNA not generally reflecting those in DNA from the colonic mucosa.

  11. Cloning and characterization of a new cold-adapted and thermo-tolerant ι-carrageenase from marine bacterium Flavobacterium sp. YS-80-122.

    PubMed

    Li, Shangyong; Hao, Jianhua; Sun, Mi

    2017-09-01

    ι-Carrageenases play a role in marine ι-carrageenan degradation, and their enzymatic hydrolysates are thought to be excellent antioxidants. In this study, we identified a new ι-carrageenase, encoded by cgiF, in psychrophilic bacterium Flavobacterium sp. YS-80-122. The deduced ι-carrageenase, CgiF, belongs to glycoside hydrolase family 82 and shows less than 40% amino acid identity with characterized ι-carrageenases. The activity of recombinant CgiF peaked at 30°C (1,207.8U/mg). Notably, CgiF is a cold-adapted ι-carrageenase, which showed 36.5% and 57% of the maximum activity at 10°C and 15°C, respectively. In addition, it is a thermo-tolerant enzyme that recovered 58.2% of its initial activity after heat shock. Furthermore, although the activity of CgiF was enhanced by NaCl, the enzyme is active in absence of NaCl. This study also shows that CgiF is an endo-type ι-carrageenase that hydrolyzes β-1,4-linkages of ι-carrageenan, yielding neo-ι-carratetraose as the main product. Its cold-adaptation, thermo-tolerance, NaCl independence and high neo-ι-carratetraose yield make CgiF an excellent candidate for industrial applications in production of ι-carrageen oligosaccharides from seaweed polysaccharides. Copyright © 2017. Published by Elsevier B.V.

  12. Disruption of the human CGI-58 homologue in Arabidopsis results in lipid droplet accumulation in the cytosol of plant cells

    USDA-ARS?s Scientific Manuscript database

    CGI-58 has been identified as the causative gene in the human neutral lipid storage disease called Chanarin-Dorfman Syndrome. This disorder results in accumulation of intracellular lipid droplets in non-adipose tissues. Here we show that disruption of the homologous CGI-58 gene in Arabidopsis thal...

  13. Effects of Guided Inquiry versus Lecture Instruction on Final Grade Distribution in a One-Semester Organic and Biochemistry Course

    ERIC Educational Resources Information Center

    Conway, Colleen J.

    2014-01-01

    A comprehensive guided-inquiry approach was used in a combined organic and biochemistry course for prenursing and predietetics students rather than lecture. To assess its effectiveness, exam grades and final course grades of students in three instructional techniques were compared. The three groups were the following: (i) lecture only, (ii)…

  14. What Works Clearinghouse Study Review Guide Instructions for Reviewing Single-Case Designs Studies

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2016

    2016-01-01

    This document provides step-by-step instructions on how to complete the Study Review Guide (SRG, Version S3, V2) for single-case designs (SCDs). Reviewers will complete an SRG for every What Works Clearinghouse (WWC) review. A completed SRG should be a reviewer's independent assessment of the study, relative to the criteria specified in the review…

  15. Articulated, Performance-Based Instruction Objectives Guide for Air Conditioning, Refrigeration, and Heating. Volume II (Second Year).

    ERIC Educational Resources Information Center

    Henderson, William Edward, Jr., Ed.

    This articulation guide contains 17 units of instruction for the second year of a two-year vocational program designed to prepare the high school graduate to install, maintain, and repair various types of residential and commercial heating, air conditioning, and refrigeration equipment. The units are designed to help the student to expand and…

  16. The Efficacy of Instructor-Guided Supplemental Instruction as a Strategy for Helping Reading-Deficient College Students Improve Testing and Assessment Outcomes

    ERIC Educational Resources Information Center

    Bartley-Lukula, Audrey

    2013-01-01

    This research project examined whether the use of Instructor-guided Supplemental Instruction as a classroom scaffolding technique, might help improve testing and assessment reading outcomes for reading-deficient college students. The study was completed at Tennessee State University in Nashville, Tennessee over the 16-week Fall, 2012 semester…

  17. An Examination of the Instruction Provided in Australian Essay Guides for Students' Development of a Critical Viewpoint

    ERIC Educational Resources Information Center

    Hammer, Sara

    2017-01-01

    The argumentative essay has endured as a popular form of university assessment, yet students still struggle to meet key intended learning outcomes, such as those associated with critical thinking. This paper presents the results of a study that examines the instruction provided by Australian essay writing guides to support students' development of…

  18. Using the DSAP Framework to Guide Instructional Design and Technology Integration in BYOD Classrooms

    ERIC Educational Resources Information Center

    Wasko, Christopher W.

    2016-01-01

    The purpose of this study was to determine the suitability of the DSAP Framework to guide instructional design and technology integration for teachers piloting a BYOD (Bring Your Own Device) initiative and to measure the impact the initiative had on the amount and type of technology used in pilot classrooms. Quantitative and qualitative data were…

  19. Connecting Cultures & Classrooms. K-12 Curriculum Guide: Language Arts, Science, Social Studies. Indian Education for All

    ERIC Educational Resources Information Center

    Fox, Sandra J., Ed.

    2006-01-01

    This curriculum guide is but one of the resources that the Montana Office of Public Instruction is providing to help teachers implement Indian Education for All. The philosophy of this document promotes the use of Indian literature as an instructional tool. There are no textbooks presently for including aspects of Montana Indian cultures into the…

  20. Firefighting for Civil Defense Emergencies; Support Assistants for Fire Emergencies. Instructor Guide--Part B.

    ERIC Educational Resources Information Center

    International Association of Fire Chiefs, New York, NY.

    This guide has been developed for use in presenting part "B" of the course of instruction for Support Assistance for Fire Emergencies. It is arranged by class sessions of three hours each. Some of the sessions are divided into two or more sections covering specific subject areas. The intention is to include instruction which will extend the…

  1. Articulated, Performance-Based Instruction Objectives Guide for Air Conditioning, Refrigeration, and Heating (Environmental Control System Installer/Servicer). Edition I.

    ERIC Educational Resources Information Center

    Henderson, William Edward, Jr., Ed.

    This articulation guide contains 17 units of instruction for the first year of a two-year vocational program designed to prepare the high school graduate to install, maintain, and repair various types of residential and commercial heating, air conditioning, and refrigeration equipment. The units are to introduce the student to fundamental theories…

  2. K-12 Resources on the Internet PLUS: Instructor's Supplement. 2nd Edition.

    ERIC Educational Resources Information Center

    Junion-Metz, Gail

    This volume is a supplement to "K-12 Resources on the Internet: An Instructional Guide" and is intended for teaching trainers that prepare Internet workshops in schools and libraries. It includes the following materials: guidelines on how to use this supplement together with the Instructional Guide in preparing a workshop; tips on how to use the…

  3. SCDC Spanish Curricula Units. Science/Math Strand, Unit 9, Grade 3, Teacher's Guide.

    ERIC Educational Resources Information Center

    Spanish Curricula Development Center, Miami Beach, FL.

    Instructional and assessment activities in science and math for third graders are presented in this teacher's guide to unit nine. Focus, objectives and materials for each activity are in English and Spanish, while teacher instructions are only in Spanish. The unit's theme is "the nation as a community"; related to the theme are the four spiraling…

  4. General Metal Trades. Book II. Units of Instruction. Teacher's Guide.

    ERIC Educational Resources Information Center

    Hohhertz, Durwin

    This teacher's guide was developed to aid in presenting units on general metal trades to students in Texas. The units are intended to provide students with basic knowledge and skills for each area of instruction in the general metal trades, and with the basic entry-level skills they will need to have in order to enter industry as trained workers.…

  5. Instructional Objectives for Junior College Courses in Economics: Principles of Macroeconomics and Principles of Microeconomics.

    ERIC Educational Resources Information Center

    Thompson, Fred A.

    These sets of behavioral objectives for junior college economics courses were written to serve as a guide to instruction, a student guide to learning, and a basis for evaluation. The objectives are offered as samples that may be used where they correspond to the skills, abilities, and attitudes other instructors want their students to acquire.…

  6. From Cooks to Carpenters: Measuring - A Saleable Work Skill. Occupation Simulation Packet. Grades 5th-6th.

    ERIC Educational Resources Information Center

    Kennedy, Helena

    This teacher's guide contains simulated work experiences for 5th and 6th grade students using the isolated skill concept - measuring. Teacher instructions include objectives, evaluation, and sequence of activities. The guide contains pre-tests and post-tests with instructions and answer keys. Three pre-skill activities are suggested, such as…

  7. Articulated, Performance-Based Instruction Objectives Guide for Machine Shop Technology.

    ERIC Educational Resources Information Center

    Henderson, William Edward, Jr., Ed.

    This articulation guide contains 21 units of instruction for two years of machine shop. The objectives of the program are to provide the student with the basic terminology and fundamental knowledge and skills in machining (year 1) and to teach him/her to set up and operate machine tools and make or repair metal parts, tools, and machines (year 2).…

  8. Teaching Guide for Indian Literature. Volume I. Reading Level 1-8.

    ERIC Educational Resources Information Center

    Campbell, Diana; McCarty, T. L., Ed.

    The guide describes how to use a 9-point system to teach 11 high-interest, low-level novels about Indians and teenagers to students reading at levels 1-8. The nine steps are (1) determine student's instructional reading level, (2) determine level of novels to be read, (3) choose novel at student's instructional reading level, (4) introduce novel,…

  9. Effect of OROS methylphenidate on encopresis in children with attention-deficit/hyperactivity disorder.

    PubMed

    Yılmaz, Savaş; Bilgiç, Ayhan; Hergüner, Sabri

    2014-04-01

    Although encopresis shows a high rate of comorbidity in patients with attention-deficit/hyperactivity disorder (ADHD), the etiologic origin of this relationship and the effect of ADHD drugs on encopresis are unclear. In this chart review, we explored the effect of OROS long-acting methylphenidate (MPH) treatment on encopresis in children with ADHD. We also evaluated the relationship between the clinical variables of ADHD and encopresis. The sample consisted of 21 children and adolescents (20 boys and 1 girl) with encopresis and coexisting ADHD 7-15 years of age. Their clinical characteristics and baseline (visit 1) and end of the second months' (visit 2) Conners' Parent Rating Scale (CPRS) subscores were recorded. Retrospective clinician determinations were made using the Clinical Global Impressions-Severity subscale (CGI-S) for encopresis severity and the Clinical Global Impressions-Improvement subscale (CGI-I) for encopresis response. According to the CGI-I, 14 subjects (71.4 %) showed much or very much improvement in their encopresis at the second visit. All of the CPRS scores showed a significant reduction during the second visit. No association was found between the CGI-I score and the changes in any of the CPRS scores. Baseline oppositional defiant disorder (ODD) and conduct disorder (CD) scores were correlated with the CGI-S score; however, no association was found between core ADHD symptom severity and the CGI-S score. With regard to the encopresis outcome, the baseline CD score was negatively correlated with the CGI-I score, and the baseline ODD score was prone to show a negative correlation with the CGI-I score. These results suggest that coexisting behavioral problems may be a vulnerability factor based on the severity of encopresis, and that MPH treatment may have a positive effect on encopresis in children and adolescents with ADHD.

  10. What does the MADRS mean? Equipercentile linking with the CGI using a company database of mirtazapine studies.

    PubMed

    Leucht, Stefan; Fennema, Hein; Engel, Rolf R; Kaspers-Janssen, Marion; Lepping, Peter; Szegedi, Armin

    2017-03-01

    Little is known about the clinical relevance of the Montgomery Asberg Depression Rating Scale (MADRS) total scores. It is unclear how total scores translate into clinical severity, or how commonly used measures for response (reduction from baseline of ≥50% in the total score) translate into clinical relevance. Moreover, MADRS based definitions of remission vary. We therefore compared: a/ the MADRS total score with the Clinical Global Impression - Severity Score (CGI-S) b/ the percentage and absolute change in the MADRS total scores with Clinical Global Impression - Improvement (CGI-I); c/ the absolute and percentage change in the MADRS total scores with CGI-S absolute change. The method used was equipercentile linking of MADRS and CGI ratings from 22 drug trials in patients with Major Depressive Disorder (MDD) (n=3288). Our results confirm the validity of the commonly used measures for response in MDD trials: a CGI-I score of 2 ('much improved') corresponded to a percentage MADRS reduction from baseline of 48-57%, and a CGI-I score of 1 ('very much improved') to a reduction of 80-84%. If a state of almost complete absence of symptoms were required for a definition of remission, a MADRS total score would be <8, because such scores corresponded to a CGI-S score of 2 ('borderline mentally ill'). Although our analysis is based on a large number of patients, the original trials were not specifically designed to examine our research question. The results might contribute to a better understanding and improved interpretation of clinical trial results in MDD. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Relationship between the clinical global impression of severity for schizoaffective disorder scale and established mood scales for mania and depression.

    PubMed

    Turkoz, Ibrahim; Fu, Dong-Jing; Bossie, Cynthia A; Sheehan, John J; Alphs, Larry

    2013-08-15

    This analysis explored the relationship between ratings on HAM-D-17 or YMRS and those on the depressive or manic subscale of CGI-S for schizoaffective disorder (CGI-S-SCA). This post hoc analysis used the database (N=614) from two 6-week, randomized, placebo-controlled studies of paliperidone ER versus placebo in symptomatic subjects with schizoaffective disorder assessed using HAM-D-17, YMRS, and CGI-S-SCA scales. Parametric and nonparametric regression models explored the relationships between ratings on YMRS and HAM-D-17 and on depressive and manic domains of the CGI-S-SCA from baseline to the 6-week end point. A clinically meaningful improvement was defined as a change of 1 point in the CGI-S-SCA score. No adjustment was made for multiplicity. Multiple linear regression models suggested that a 1-point change in the depressive domain of CGI-S-SCA corresponded to an average 3.6-point (SE=0.2) change in HAM-D-17 score. Similarly, a 1-point change in the manic domain of CGI-S-SCA corresponded to an average 5.8-point (SE=0.2) change in YMRS score. Results were confirmed using local and cumulative logistic regression models in addition to equipercentile linking. Lack of subjects scoring over the complete range of possible scores may limit broad application of the analyses. Clinically meaningful score changes in depressive and manic domains of CGI-S-SCA corresponded to approximately 4- and 6-point score changes on HAM-D-17 and YMRS, respectively, in symptomatic subjects with schizoaffective disorder. Copyright © 2013 Elsevier B.V. All rights reserved.

  12. SU-F-T-17: A Feasibility Study for the Transit Dosimetry with a Glass Dosimeter in Brachytherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moon, S; Yoon, M; Chung, W

    Purpose: Confirming the dose delivered to a patient is important to make sure the treatment quality and safety of the radiotherapy. Measuring a transit dose of the patient during the radiotherapy could be an interesting way to confirm the patient dose. In this study, we evaluated the feasibility of the transit dosimetry with a glass dosimeter in brachytherapy. Methods: We made a phantom that inserted the glass dosimeters and placed under patient lying on a couch for cervix cancer brachytherapy. The 18 glass dosimeters were placed in the phantom arranged 6 per row. A point putting 1cm vertically from themore » source was prescribed as 500.00 cGy. Solid phantoms of 0, 2, 4, 6, 8, 10 cm were placed between the source and the glass dosimeter. The transit dose was measured each thickness using the glass dosimeters and compared with a treatment planning system (TPS). Results: When the transit dose was smaller than 10 cGy, the average of the differences between measured values and calculated values by TPS was 0.50 cGy and the standard deviation was 0.69 cGy. If the transit dose was smaller than 100 cGy, the average of the error was 1.67 ± 4.01 cGy. The error to a point near the prescription point was −14.02 cGy per 500.00 cGy of the prescription dose. Conclusion: The distances from the sources to skin of the patient generally are within 10 cm for cervix cancer cases in brachytherapy. The results of this preliminary study showed the probability of the glass dosimeter as the transit dosimeter in brachytherapy.« less

  13. COATING ALTERNATIVES GUIDE (CAGE) USER'S GUIDE (EPA/600/R-01/030)

    EPA Science Inventory

    The guide provides instructions for using the Coating Alternatives GuidE (CAGE) software program, version 1.0. It assumes that the user is familiar with the fundamentals of operating an IBM-compatible personal computer (PC) under the Microsoft disk operating system (MS-DOS). CAGE...

  14. Enhancing an Instructional Design Model for Virtual Reality-Based Learning

    ERIC Educational Resources Information Center

    Chen, Chwen Jen; Teh, Chee Siong

    2013-01-01

    In order to effectively utilize the capabilities of virtual reality (VR) in supporting the desired learning outcomes, careful consideration in the design of instruction for VR learning is crucial. In line with this concern, previous work proposed an instructional design model that prescribes instructional methods to guide the design of VR-based…

  15. Fiber, Fabric, and Fashion. Clothing and Textiles Curriculum. Environment I.

    ERIC Educational Resources Information Center

    Arizona State Univ., Tempe.

    A competency-based instructional guide for grades 7-14, this volume is one of three parts, each of which focuses on a different instructional environment (psychomotor, cognitive, or affective) for clothing or fashion instruction, and each of which includes competencies and corresponding learning activities for each of three instructional levels.…

  16. The Impact of Guidance during Problem-Solving Prior to Instruction on Students' Inventions and Learning Outcomes

    ERIC Educational Resources Information Center

    Loibl, Katharina; Rummel, Nikol

    2014-01-01

    Multiple studies have shown benefits of problem-solving prior to instruction (cf. Productive Failure, Invention) in comparison to direct instruction. However, students' solutions prior to instruction are usually erroneous or incomplete. In analogy to "guided" discovery learning, it might therefore be fruitful to lead students…

  17. Tune Up: Automotive Mechanics Instructional Program. Block 5.

    ERIC Educational Resources Information Center

    O'Brien, Ralph D.

    The fifth of six instructional blocks in automotive mechanics, the lessons and supportive information in the document provide a guide for teachers in planning an instructional program in automotive tune-ups at the secondary and post secondary level. The material, as organized, is a suggested sequence of instruction within each block. Each lesson…

  18. Fuel System: Automotive Mechanics Instructional Program. Block 4.

    ERIC Educational Resources Information Center

    O'Brien, Ralph D.

    The fourth of six instructional blocks in automotive mechanics, the lessons and supportive information in the document provide a guide for teachers in planning an instructional program in automotive fuel systems at the secondary and post secondary level. The material, as organized, is a suggested sequence of instruction within each block. Each…

  19. Fundamentals of Concrete and Cement Masonry. Instructional Materials.

    ERIC Educational Resources Information Center

    Hendrix, Laborn J.

    This curriculum guide provides materials for a course of instruction designed for training concrete masons who will make their careers in construction. It contains 4 sections and 18 instructional units in a standard format. Eight basic components that form a unit of instruction are performance objectives, suggested activities for the teacher,…

  20. Cooling System: Automotive Mechanics Instructional Program. Block 6.

    ERIC Educational Resources Information Center

    O'Brien, Ralph D.

    The last of six instructional blocks in automotive mechanics, the lessons and supportive information in the document provide a guide for teachers in planning an instructional program in the automotive cooling system at the secondary and post secondary level. The material, as organized, is a suggested sequence of instruction within each block. Each…

  1. Food Production, Management, and Services. Production. Teacher Edition. Second Edition.

    ERIC Educational Resources Information Center

    Gibson, LeRoy

    This teacher's guide contains 20 units of instruction for a course in production in the food production, management, and services area. Units of instruction are designed for use in more than one lesson or class period of instruction. Introductory materials include the following: a competency profile; instructional/task analysis; related academic…

  2. Leading Instructional Rounds in Education: A Facilitator?'s Guide. Instructional Rounds Series

    ERIC Educational Resources Information Center

    Fowler-Finn, Thomas

    2013-01-01

    Instructional rounds is a powerful form of professional learning aimed at helping schools and systems develop the capacity to educate all children to high levels. In this practical book, Thomas Fowler-Finn, an experienced consultant who has worked closely with the Harvard team that pioneered instructional rounds, discusses how facilitators can…

  3. SU-F-T-448: Use of Mixed Photon Energy Beam in Volumetric Modulated Arc Therapy (VMAT) Treatment Plan for Prostate Cancer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Manigandan, D; Kumar, M; Mohandas, P

    Purpose: To study the impact of different photon beam combination during VMAT planning and treatment delivery. Methods: Five prostate patients with no nodal involvement were chosen for the study and only prostate was considered as target (7920cGy/44fractions). In each case, three different VMAT plans were generated with two arcs (200°–160°&160°–200°). First plan used only 6MV in both arcs (6X-6X) and second utilized 6MV&15MV (6X-15X), whereas third one used 15MV&15MV (15X-15X). For consistency, all the plans were generated by the same planner using Monaco− treatment planning system (V5.1) for Elekta Synergy− linear accelerator with 1cm leaf-width. For plan comparison, target meanmore » dose, conformity index (CI)=Planning target volume (PTV) covered by 95% of prescription dose/PTV were analyzed. Mean doses of bladder, rectum, left femur and right femur were analyzed. Integral dose (liter-Gray) to normal tissue (patient volume minus PTV), total monitor unit (MU) required to deliver a plan and gamma pass rate for each plan was analyzed. Results: The CI for PTV was 0.9937±0.0037, 0.9917±0.0033, and 0.9897±0.0048 for 6X-6X, 6X-15X and 15X-15X, respectively. Mean dose to target slightly increases with the decrease of energy. Mean doses to bladder were 3546.23±692.13cGy, 3487.43±715.53cGy and 3504.40±683.1cGy for 6X-6X, 6X-15X and 15X-15X, respectively. Mean doses to rectum were 4294.60±309.5cGy, 4277.07±279.93cGy and 4290.77±379.07cGy. Mean doses to left femur were 2737.13±545.93cGy, 2668.67±407.12cGy and 2416.77±300.73cGy and mean doses to the right femur were 2682.70±460.81cGy, 2722.58±541.92cGy and 2598.57±481.83cGy. Higher Integral doses to normal tissue observed for 6X-6X (163.06±24.6 Litre-Gray) followed by 6X-15X (154.35±24.74 Litre-Gray) and 15X-15X (145.84±26.03 Litre-Gray). Average MU required to deliver one fraction was 680.75±72.09, 634.81±95.07 and 605.06±114.65. Gamma pass rates were 99.83±0.21, 99.53±0.27 and 99.2±0.20. Conclusion: 6X-15X VMAT plan offer dosimetric advantage compared to 6X-6X in terms of lesser MU and integral dose without significant compromise in plan quality, where as in 15X-15X, neutron contamination risk is relatively higher.« less

  4. Cleaning Services.

    ERIC Educational Resources Information Center

    Sharpton, James L.

    This curriculum guide provides cleaning services instructional materials for a ninth- and tenth-grade Coordinated Vocational Education and Training: Home and Community Services program. It includes 2 sections and 11 instructional units. Each unit of instruction consists of eight basic components: performance objectives, teacher activities,…

  5. Residential Carpentry.

    ERIC Educational Resources Information Center

    Hendrix, Laborn J.

    This curriculum guide provides instructional materials for a course to train carpenters who will make careers in construction. It includes 6 sections and 21 instructional units. Each unit of instruction consists of eight basic components: performance objectives, teacher activities, information sheets (content essential for meeting the cognitive…

  6. Calculating Clinically Significant Change: Applications of the Clinical Global Impressions (CGI) Scale to Evaluate Client Outcomes in Private Practice

    ERIC Educational Resources Information Center

    Kelly, Peter James

    2010-01-01

    The Clinical Global Impressions (CGI) scale is a therapist-rated measure of client outcome that has been widely used within the research literature. The current study aimed to develop reliable and clinically significant change indices for the CGI, and to demonstrate its application in private psychological practice. Following the guidelines…

  7. SAGE FOR WINDOWS (WSAGE) VERSION 1.0 SOLVENT ALTERNATIVES GUIDE - USER'S GUIDE

    EPA Science Inventory

    The guide provides instructions for using the Solvent Alternatives Guide (SAGE) for Windows, version 1.0. The guide assumes that the user is familiar with the fundamentals of operating Windows 3.1 (or higher) on a personal computer under the DOS 5.0 (or higher) operating system. ...

  8. SAGE FOR MACINTOSH (MSAGE) VERSION 1.0 SOLVENT ALTERNATIVES GUIDE - USER'S GUIDE

    EPA Science Inventory

    The guide provides instructions for using the Solvent Alternatives Guide (SAGE) for Macintosh, version 1.0. The guide assumes that the user is familiar with the fundamentals of operating a
    Macintosh personal computer under the System 7.0 (or higher) operating system. SAGE for ...

  9. Water Resource Management. [Student Guide] and Teacher's Guide.

    ERIC Educational Resources Information Center

    Young, Donald B.; Pottenger, Francis M.

    This student guide and accompanying teacher's guide are a product of the Foundational Approaches in Science Teaching (FAST) curriculum development project at the University of Hawaii. In the teaching guide, the introduction gives a description of the underlying theory and practice in FAST and includes the FAST instructional model, descriptions of…

  10. The simple neuroendocrine-immune regulatory network in oyster Crassostrea gigas mediates complex functions.

    PubMed

    Liu, Zhaoqun; Wang, Lingling; Zhou, Zhi; Sun, Ying; Wang, Mengqiang; Wang, Hao; Hou, Zhanhui; Gao, Dahai; Gao, Qiang; Song, Linsheng

    2016-05-19

    The neuroendocrine-immune (NEI) regulatory network is a complex system, which plays an indispensable role in the immunity of the host. In the present study, the bioinformatical analysis of the transcriptomic data from oyster Crassostrea gigas and further biological validation revealed that oyster TNF (CgTNF-1 CGI_10018786) could activate the transcription factors NF-κB and HSF (heat shock transcription factor) through MAPK signaling pathway, and then regulate apoptosis, redox reaction, neuro-regulation and protein folding in oyster haemocytes. The activated immune cells then released neurotransmitters including acetylcholine, norepinephrine and [Met(5)]-enkephalin to regulate the immune response by arising the expression of three TNF (CGI_10005109, CGI_10005110 and CGI_10006440) and translocating two NF-κB (Cgp65, CGI_10018142 and CgRel, CGI_10021567) between the cytoplasm and nuclei of haemocytes. Neurotransmitters exhibited the immunomodulation effects by influencing apoptosis and phagocytosis of oyster haemocytes. Acetylcholine and norepinephrine could down-regulate the immune response, while [Met(5)]-enkephalin up-regulate the immune response. These results suggested that the simple neuroendocrine-immune regulatory network in oyster might be activated by oyster TNF and then regulate the immune response by virtue of neurotransmitters, cytokines and transcription factors.

  11. The simple neuroendocrine-immune regulatory network in oyster Crassostrea gigas mediates complex functions

    NASA Astrophysics Data System (ADS)

    Liu, Zhaoqun; Wang, Lingling; Zhou, Zhi; Sun, Ying; Wang, Mengqiang; Wang, Hao; Hou, Zhanhui; Gao, Dahai; Gao, Qiang; Song, Linsheng

    2016-05-01

    The neuroendocrine-immune (NEI) regulatory network is a complex system, which plays an indispensable role in the immunity of the host. In the present study, the bioinformatical analysis of the transcriptomic data from oyster Crassostrea gigas and further biological validation revealed that oyster TNF (CgTNF-1 CGI_10018786) could activate the transcription factors NF-κB and HSF (heat shock transcription factor) through MAPK signaling pathway, and then regulate apoptosis, redox reaction, neuro-regulation and protein folding in oyster haemocytes. The activated immune cells then released neurotransmitters including acetylcholine, norepinephrine and [Met5]-enkephalin to regulate the immune response by arising the expression of three TNF (CGI_10005109, CGI_10005110 and CGI_10006440) and translocating two NF-κB (Cgp65, CGI_10018142 and CgRel, CGI_10021567) between the cytoplasm and nuclei of haemocytes. Neurotransmitters exhibited the immunomodulation effects by influencing apoptosis and phagocytosis of oyster haemocytes. Acetylcholine and norepinephrine could down-regulate the immune response, while [Met5]-enkephalin up-regulate the immune response. These results suggested that the simple neuroendocrine-immune regulatory network in oyster might be activated by oyster TNF and then regulate the immune response by virtue of neurotransmitters, cytokines and transcription factors.

  12. SAGE 2.0 SOLVENT ALTERNATIVES GUIDE - USER'S GUIDE

    EPA Science Inventory

    The guide provides instruction for using the SAGE (Solvent Alternatives Guide) software system, version 2.O. It assumes that the user is familiar with the fundamentals of operating a personal computer under the Microsoft disk operating system (MS-DOS). AGE recommends solvent repl...

  13. A Methodological Study Evaluating a Pretutorial Computer-Compiled Instructional Program in High School Physics Instruction Initiated from Student-Teacher Selected Instructional Objectives. Final Report.

    ERIC Educational Resources Information Center

    Leonard, B. Charles; Denton, Jon J.

    A study sought to develop and evaluate an instructional model which utilized the computer to produce individually prescribed instructional guides to account for the idiosyncratic variations among students in physics classes at the secondary school level. The students in the treatment groups were oriented toward the practices of selecting…

  14. Prevention of hypothyroidism related to mantle irradiation for Hodgkin's disease: Preparative phantom study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marcial-Vega, V.A.; Order, S.E.; Lastner, G.

    1990-03-01

    To decrease the incidence of hypothyroidism related to mantle irradiation for Hodgkin's disease, we initiated a study designed to protect the thyroid gland using a phantom. A thyroid phantom was filled with technetium-99m. The thyroid phantom was placed inside of its corresponding anterior neck position in a whole body phantom. An anterior scintiscan of the head and neck region demonstrated the radioactivity in the simulated thyroid. A mantle port included a focused block that would shield the thyroid from the anterior port. The phantom was exposed (4 MeV) to 180 cGy (AP-PA) at midplane with lithium fluoride dosimeters in themore » position of the thyroid. The thyroid received an average of 12 cGy from the anterior field and 48 cGy from the posterior field for a total of 60 cGy per treatment or 30% of the prescribed dose. A complete mantle field course of radiation of 4000 cGy would lead to a thyroid dose of 1200 cGy at a daily fractional dose of 60 cGy. We elected not to block the thyroid from the posterior field to prevent shielding and potential underdosage of involved nodal sites. The present study suggests a method of safe and effective thyroid shielding which needs to be tested clinically to determine whether it would reduce the incidence of chemical and clinical hypothyroidism or simply extend the period until occurrence.« less

  15. The Digestive System [and] Instructor's Guide. Instructional Materials in Anatomy and Physiology for Pennsylvania Health Occupations Programs.

    ERIC Educational Resources Information Center

    National Evaluation Systems, Inc., Amherst, MA.

    This instructional modular unit wlth instructor's guide provides materials on important aspects of one of the major systems of the human body--the digestive system. Its purpose is to introduce the student to the structures and functions of the human digestive system--and the interrelationships of the two--and to familiarize the student with some…

  16. The Effects of Guided Reading Instruction on the Reading Comprehension and Reading Attitudes of Fourth-Grade At-Risk Students

    ERIC Educational Resources Information Center

    Bruce, Laquanda T.

    2010-01-01

    America's public schools have faced challenges in educating students, particularly those identified as at risk. According to the No Child Left Behind Act, nearly 70% of 4th grade students are unable to perform on a basic level on national reading tests. The research problem in this study addressed the significance of guided reading instruction,…

  17. Making an Adjustable C-Clamp. Kit No. 603. Instructor's Manual [and] Student Learning Activity Manual. [Revised.] T & I--Metalwork.

    ERIC Educational Resources Information Center

    White, Jim; Alexander, Larry

    This student activity kit consists of a programmed, self-instructional learning guide and an accompanying instructor's manual for use in teaching trade and industrial education students how to make an adjustable C-clamp. The student guide contains step-by-step instructions in the following areas: basic layout principles; use of a hack saw, file,…

  18. Paul Bunyan Takes A Wife--Developing Language, Reading, and Thinking Abilities through Creative Arts: An Alternative to Performance Centered Instruction.

    ERIC Educational Resources Information Center

    Ward, Pat; And Others

    This guide, designed for the elementary level, contains written and oral language activities involving the five senses which are intended to help teachers develop enthusiastic readers. The guide's five sections are as follows: (1) My Very Own Paul Bunyan Songbook; (2) A Logger's Log; (3) Teacher's Instructions for the Magic Wall and Parachute…

  19. SCDC Spanish Curricula Units. Science/Math Strand, Unit 5, Grade 2, Teacher's Guide--Multi-Ethnic Edition.

    ERIC Educational Resources Information Center

    Operations Research Society of America, Arlington, VA.

    Continuing the theme of the school as a community, the teacher's guide to the science/math strand of unit five presents both instructional and assessment activities for kits 17-20. Focus, materials and objective for each activity are in Spanish and English; teacher instructions are in Spanish only. In kit 17 the science activities deal with the…

  20. Instructional Principles for Online Learning

    ERIC Educational Resources Information Center

    Chang, Shujen L.

    2004-01-01

    Four instructional principles for alleviating cognitive overload in online learning are suggested: 1) Guide learners to prepare and maintain an effective workstation for accessing online materials, 2) Employ advance organizers for effective online navigation, 3) Arrange instructional materials for easy online manipulation, and 4) Organize…

  1. High speed turning of compacted graphite iron using controlled modulation

    NASA Astrophysics Data System (ADS)

    Stalbaum, Tyler Paul

    Compacted graphite iron (CGI) is a material which emerged as a candidate material to replace cast iron (CI) in the automotive industry for engine block castings. Its thermal and mechanical properties allow the CGI-based engines to operate at higher cylinder pressures and temperatures than CI-based engines, allowing for lower fuel emissions and increased fuel economy. However, these same properties together with the thermomechanical wear mode in the CGI-CBN system result in poor machinability and inhibit CGI from seeing wide spread use in the automotive industry. In industry, machining of CGI is done only at low speeds, less than V = 200 m/min, to avoid encountering rapid wear of the cutting tools during cutting. Studies have suggested intermittent cutting operations such as milling suffer less severe tool wear than continuous cutting. Furthermore, evidence that a hard sulfide layer which forms over the cutting edge in machining CI at high speeds is absent during machining CGI is a major factor in the difference in machinability of these material systems. The present study addresses both of these issues by modification to the conventional machining process to allow intermittent continuous cutting. The application of controlled modulation superimposed onto the cutting process -- modulation-assisted machining (MAM) -- is shown to be quite effective in reducing the wear of cubic boron nitride (CBN) tools when machining CGI at high machining speeds (> 500 m/min). The tool life is at least 20 times greater than found in conventional machining of CGI. This significant reduction in wear is a consequence of reduction in the severity of the tool-work contact conditions with MAM. The propensity for thermochemical wear of CBN is thus reduced. It is found that higher cutting speed (> 700 m/min) leads to lower tool wear with MAM. The MAM configuration employing feed-direction modulation appears feasible for implementation at high speeds and offers a solution to this challenging class of industrial machining applications. This study's approach is by series of high speed turning tests of CGI with CBN tools, comparing conventional machining to MAM for similar parameters otherwise, by tool wear measurements and machinability observations.

  2. Categorical improvements in disease severity in patients with major depressive disorder treated with vilazodone: post hoc analysis of four randomized, placebo-controlled trials.

    PubMed

    Durgam, Suresh; Chen, Changzheng; Gommoll, Carl P; Edwards, John; Citrome, Leslie

    2016-01-01

    In three 8-week studies of vilazodone 40 mg/d (NCT00285376, NCT00683592, and NCT01473394) and a 10-week study of vilazodone 20 or 40 mg/d (NCT01473381), adults with major depressive disorder (MDD) showed significantly greater improvement with vilazodone versus placebo in global disease severity as measured by mean change from baseline in Clinical Global Impression of Severity (CGI-S) score. To assess the proportion of patients achieving clinically meaningful improvement, a post hoc pooled analysis was conducted using categorical shifts in disease severity based on CGI-S scores at baseline and end of treatment (EOT). Analyses were conducted in the pooled intent-to-treat population (N=2,218). Definitions of categorical shifts included CGI-S ≥4 (moderately ill or worse) at baseline to CGI-S ≤2 (normal or borderline ill) at EOT; CGI-S ≥5 (markedly ill or worse) at baseline to CGI-S ≤2 at EOT; and CGI-S ≥6 (severely ill or worse) at baseline to CGI-S ≤3 (mildly ill or better) at EOT. At baseline, 2,217 patients were moderately ill or worse. The percentage who improved to normal or borderline ill was significantly higher with vilazodone than with placebo (40.0% versus 27.8%; odds ratio [OR] =1.7, P <0.001; number needed to treat [NNT] =9). In the 979 patients who were markedly ill or worse at baseline, the percentage who improved to normal or borderline ill was significantly higher with vilazodone than with placebo (36.8% versus 25.5%; OR =1.7, P <0.001; NNT =9). The small number of severely ill patients at baseline (n =43) provided inadequate power to detect statistically significant between-group differences, but an NNT =5 was found for improvement to mildly ill or better. Categorical shift analyses, defined using baseline and EOT CGI-S scores, showed that significantly higher proportions of patients had clinically meaningful improvements in global disease severity with vilazodone 20-40 mg/d versus placebo. This type of analysis may be useful for evaluating the effects of antidepressant treatment in adults with MDD.

  3. A Fresh Cadaver Model for the Instruction of Ultrasound-Guided Fine-Needle Aspiration of Thyroid Nodules.

    PubMed

    McCrary, Hilary C; Faucett, Erynne A; Hurbon, Audriana N; Milinic, Tijana; Cervantes, Jose A; Kent, Sean L; Adamas-Rappaport, William J

    2017-07-01

    Objective The aim of our study is to determine if a fresh cadaver model (FCM) for the instruction of ultrasound (US)-guided fine-needle aspiration (FNA) of thyroid nodules is a practical method for instruction. Study Design Pre- and postinstruction assessment of medical students' ability to perform US-guided FNA of artificially created thyroid nodules placed adjacent to the thyroid gland of a fresh cadaver. Setting University-based fresh cadaver laboratory. Subjects and Methods Study participants included a total of 17 first- and second-year medical students with minimal US training. Technical skills were assessed using a 10-item checklist. In addition, a cognitive assessment regarding the indications, contraindications, and complications of the procedure was completed. A postinstruction assessment was provided for participants 5 weeks after their initial assessment. Differences between pre- and postinstruction assessment scores of technical skills were analyzed using McNemar's test. The mean cognitive knowledge gain was analyzed using a paired 2-sample t test. Results Eight of 10 items on the skills checklist were statistically significant between pre- and postinstruction skills assessment ( P < .05). There was a statistically significant change in cognitive knowledge gain regarding the contraindications of the procedure ( P = .001), but not for indications or complications ( P = .104 and P = .111, respectively). Conclusion US-guided FNA continues to be an important diagnostic procedure in the workup of thyroid nodules, making it an essential skill to integrate into surgical skills lab. Our FCM for the instruction of US-guided FNA is the first of its kind, and this pilot study shows this is a viable method for instruction.

  4. Applying Case-Based Method in Designing Self-Directed Online Instruction: A Formative Research Study

    ERIC Educational Resources Information Center

    Luo, Heng; Koszalka, Tiffany A.; Arnone, Marilyn P.; Choi, Ikseon

    2018-01-01

    This study investigated the case-based method (CBM) instructional-design theory and its application in designing self-directed online instruction. The purpose of this study was to validate and refine the theory for a self-directed online instruction context. Guided by formative research methodology, this study first developed an online tutorial…

  5. A Methodological Study of a Computer-Managed Instructional Program in High School Physics.

    ERIC Educational Resources Information Center

    Denton, Jon James

    The purpose of this study was to develop and evaluate an instructional model which utilized the computer to produce individually prescribed instructional guides in physics at the secondary school level. The sample consisted of three classes. Of these, two were randomly selected to serve as the treatment groups, e.g., individualized instruction and…

  6. A History of Reading Programs Involving Instruction in the Content Areas, 1966-1981.

    ERIC Educational Resources Information Center

    Wadleigh, Merritt Edward

    Six questions guided a literature review of content area reading instruction in American secondary schools since 1966: (1) What is the history of reading instruction in American secondary schools through 1965? (2) Why is reading instruction at the secondary level important? (3) What are some factors both within and without secondary schools that…

  7. Conceptualizing Relations between Instructional Guidance Infrastructure (IGI) and Teachers' Beliefs about Mathematics Instruction: Regulative, Normative, and Cultural-Cognitive Considerations

    ERIC Educational Resources Information Center

    Hopkins, Megan; Spillane, James P.

    2015-01-01

    Scholars have become increasingly interested in what is often referred to as the instructional guidance infrastructure (IGI). Research has identified the characteristics of infrastructures that make them more or less influential in guiding teachers' instruction, such as alignment, authority, and prescriptiveness. Although these are important, a…

  8. Improving Instruction through Schoolwide Professional Development: Effects of the Data-on-Enacted-Curriculum Model

    ERIC Educational Resources Information Center

    Blank, Rolf K.; Smithson, John; Porter, Andrew; Nunnaley, Diana; Osthoff, Eric

    2006-01-01

    The instructional improvement model Data on Enacted Curriculum was tested with an experimental design using randomized place-based trials. The improvement model is based on using data on instructional practices and achievement to guide professional development and decisions to refocus on instruction. The model was tested in 50 U.S. middle schools…

  9. Library Study Guide for Business.

    ERIC Educational Resources Information Center

    Steidinger, Jana Reeg; Trzebiatowski, Elaine

    This library study guide was designed for business marketing students at the University of Wisconsin, Stout. The guide, and its accompanying exercises, were developed as an alternative to providing library instruction to approximately 150 business marketing students each semester. The guide introduces students to basic business reference sources…

  10. South Carolina Guide for Introduction to Marketing.

    ERIC Educational Resources Information Center

    Vaughan, Ellen C.; Elliott, Ronald T.

    This introduction to marketing guide addresses the three domains of learning: psychomotor, cognitive, and affective. The guide contains suggestions for specific classroom activities for each domain. Each unit or task in this guide contains a competency statement followed by performance objectives, job-relevant instructional activities,…

  11. A comparison of literature-based and content-based guided reading materials on elementary student reading and science achievement

    NASA Astrophysics Data System (ADS)

    Guns, Christine

    Guided reading, as developed by Fountas and Pinnell (2001), has been a staple of elementary reading programs for the past decade. Teachers in the elementary school setting utilize this small group, tailored instruction in order to differentiate and meet the instructional needs of the students. The literature shows academic benefit for students who have special needs, such as learning disabilities, autism, and hearing impairments but consideration of academic impact has not been investigated for regular education students. The purpose of this quasi-experimental study was to investigate the academic impact of the use of content-related (Group C) and the traditional literature-based (Group L) reading materials. During the Living Systems and Life Processes unit in science, two teachers self-selected to utilized science-related materials for guided reading instruction while the other three teacher participants utilized their normal literature-based guided reading materials. The two groups were compared using an ANCOVA in this pre-test/post-test design. The dependent variables included the Reading for Application and Instruction assessment (RAI) and a Living Systems and Life Processes assessment (LSA). Further analysis compared students of different reading levels and gender. The data analyses revealed a practical but not statistical significance for students in science performance. It was discovered that below level male and female students performed better on the LSA when provided with content-related guided reading materials. As far as reading achievement is concerned, students in both groups had comparable results. The teachers provided guided reading instruction to their students with fidelity and made adjustments to their practices due to the needs of their students. The content-related teachers utilized a larger number of expository texts than the literature-based teachers. These teachers expressed the desire to continue the practice of providing the students with content-related materials.

  12. See Also:physica status solidi (a)physica status solidi (c)Copyright © 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

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  1. Escaparate. Programa de lectura y ensenanza del lenguaje, Unidad C. Guia Para El Maestro (Show Window. Reading and Language Learning Program, Unit C. Teacher's Guide).

    ERIC Educational Resources Information Center

    Dissemination and Assessment Center for Bilingual Education, Austin, TX.

    Instructions for use of "Escaparate," the third of eight Spanish reading and language instruction units developed by Edgewood School District's Bilingual Program, San Antonio, Texas, are given in this teacher guide. Originally intended for grades four through six, the program may be used from fourth grade to secondary school in Spanish reading and…

  2. The Ancient Greeks Speak to Us: A New Humanistic Approach to Classical Greek and Greek Culture for Secondary Schools. Teacher's Guide-Level Alpha.

    ERIC Educational Resources Information Center

    Masciantonio, Rudolph; And Others

    A humanistic approach to the study of classical Greek and Greek culture at the secondary school level is detailed in this guide. References to the student programed text and other multisensory instructional materials used in the system focus on instructional objectives geared to students who are not necessarily college-bound. The standard Attic…

  3. Measure for Measure: A Critical Consumers' Guide to Reading Comprehension Assessments for Adolescents. Final Report from Carnegie Corporation of New York's Council on Advancing Adolescent Literacy

    ERIC Educational Resources Information Center

    Morsy, Leila; Kieffer, Michael; Snow, Catherine

    2010-01-01

    Although millions of dollars and weeks of instructional time are spent nationally on testing students, educators often have little information on how to choose appropriate assessments of adolescent reading for informing instruction. This guide is designed to meet that need, by drawing together evidence about nine of the most commonly-used,…

  4. Managerial Accounting. Study Guide.

    ERIC Educational Resources Information Center

    Plachta, Leonard E.

    This self-instructional study guide is part of the materials for a college-level programmed course in managerial accounting. The study guide is intended for use by students in conjuction with a separate textbook, Horngren's "Accounting for Management Control: An Introduction," and a workbook, Curry's "Student Guide to Accounting for Management…

  5. Role of Ovarian Transposition Based on the Dosimetric Effects of Craniospinal Irradiation on the Ovaries: A Case Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mitchell, James D.; Hitchen, Christine; Vlachaki, Maria T.

    2007-10-01

    In this study, we present a case of laparoscopic ovarian transposition to preserve ovarian function in an adult female patient treated with craniospinal irradiation for standard risk medulloblastoma. The prescribed dose to the craniospinal axis was 2340 cGy at 180 cGy per fraction and was delivered with 6-MV photons. Before ovarian transposition, magnetic resonance imaging (MRI) of the pelvis was obtained for localization of the ovaries and was registered with the planning computed tomography (CT) scan. Surgical clips allowed for CT localization of the ovaries after transposition. As a result of ovarian transposition, mean and maximum radiation doses decreased frommore » 983 to 68 cGy and 1624 to 84 cGy for the left ovary and from 166 to 87 cGy and 723 to 103 cGy for the right ovary, respectively. Review of the literature indicates that such radiation doses are below the threshold that causes ovarian dysfunction and infertility. We conclude that ovarian localization with an MRI of the pelvis can be offered to females undergoing craniospinal irradiation. Transposition of the ovaries provides an option to preserve ovarian function in cases where the ovaries would otherwise be included within the radiation field.« less

  6. A SoxC gene related to larval shell development and co-expression analysis of different shell formation genes in early larvae of oyster.

    PubMed

    Liu, Gang; Huan, Pin; Liu, Baozhong

    2017-06-01

    Among the potential larval shell formation genes in mollusks, most are expressed in cells surrounding the shell field during the early phase of shell formation. The only exception (cgi-tyr1) is expressed in the whole larval mantle and thus represents a novel type of expression pattern. This study reports another gene with such an expression pattern. The gene encoded a SoxC homolog of the Pacific oyster Crassostrea gigas and was named cgi-soxc. Whole-mount in situ hybridization revealed that the gene was highly expressed in the whole larval mantle of early larvae. Based on its spatiotemporal expression, cgi-soxc is hypothesized to be involved in periostracum biogenesis, biomineralization, and regulation of cell proliferation. Furthermore, we investigated the interrelationship between cgi-soxc expression and two additional potential shell formation genes, cgi-tyr1 and cgi-gata2/3. The results confirmed co-expression of the three genes in the larval mantle of early D-veliger. Nevertheless, cgi-gata2/3 was only expressed in the mantle edge, and the other two genes were expressed in all mantle cells. Based on the spatial expression patterns of the three genes, two cell groups were identified from the larval mantle (tyr1 + /soxc + /gata2/3 + cells and tyr1 + /soxc + /gata2/3 - cells) and are important to study the differentiation and function of this tissue. The results of this study enrich our knowledge on the structure and function of larval mantle and provide important information to understand the molecular mechanisms of larval shell formation.

  7. Unique patterns of CpG island methylation in inflammatory bowel disease-associated colorectal cancers

    PubMed Central

    Olaru, Alexandru V.; Cheng, Yulan; Agarwal, Rachana; Yang, Jian; David, Stefan; Abraham, John M.; Yu, Wayne; Lazarev, Mark; Brant, Steven R.; Marohn, Michael R.; Hutcheon, David F.; Harpaz, Noam; Meltzer, Stephen J.; Mori, Yuriko

    2011-01-01

    Objective CpG island (CGI) hypermethylation at discrete loci is a prevalent cancer-promoting abnormality in sporadic colorectal carcinomas (S-CRCs). We investigated genome-wide CGI methylation in inflammatory bowel disease (IBD)-associated CRCs (IBD-CRCs). Design Methylation microarray analyses were conducted on 7 IBD-CRCs, 17 S-CRCs, and 8 normal control colonic tissues from patients without CRC or IBD. CGI methylator phenotype (CIMP), a surrogate marker for widespread cancer-specific CGI hypermethylation, was examined in 30 IBD-CRCs and 43 S-CRCs. Results The genome-wide CGI methylation pattern of IBD-CRCs was CIMP status-dependent. Based on methylation array data profiling of all autosomal loci, CIMP+ IBD-CRCs grouped together with S-CRCs, while CIMP− IBD-CRCs grouped together with control tissues. CIMP− IBD-CRCs demonstrated less methylation than did age-matched CIMP− S-CRCs at all autosomal CGIs (z-score −0.17 vs. 0.09, p=3×10−3) and CRC-associated hypermethylation target CGIs (z-score −0.43 vs. 0.68, p=1×10-4). Age-associated hypermethylation target CGIs were significantly overrepresented in CGIs that were hypermethylated in S-CRCs (p=1×10−192), but not in CGIs that were hypermethylated in IBD-CRCs (p=0.11). In contrast, KRAS mutation prevalence were similar between IBD-CRCs and S-CRCs. Notably, CIMP+ prevalence was significantly higher in older than in younger IBD-CRC cases (4.2% vs. 50.0%, p=0.02), but not in S-CRC cases (16.7% vs. 9.7%, p=0.92). Conclusions Cancer-specific CGI hypermethylation and age-associated CGI hypermethylation are diminished in IBD-CRCs relative to S-CRCs, while KRAS mutation rate is comparable between these cancers. CGI hypermethylation appears to play only a minor role in IBD-associated carcinogenesis. We speculate that aging, rather than inflammation per se, promotes CIMP+ CRCs in IBD patients. PMID:21830278

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Santoro, J; Witten, M; Haas, J

    Purpose: Brachytherapy has been the standard of care for cervical cancer for 100 years. The treatment can be administered using an HDR (high dose rate) remote afterloader with a {sup 192}Ir source in an outpatient setting, a PDR afterloader with a {sup 192}Ir source, or with LDR manually loaded or a remote afterloader utilizing {sup 192}Ir or {sup 137}Cs sources in an inpatient setting. The procedure involves the placement of a tandem and ovoid, tandem and ring, or tandem and cylinder applicator in an operating room setting with the patient under general anesthesia. Inaccuracies introduced into the process occurring betweenmore » placement of the applicator and actual delivery can introduce uncertainty into the actual dose delivered to the tumor and critical organs. In this study we seek to investigate the dosimetric difference between an SBRT-based radiotherapy boost and conventional Brachytherapy in treating cervical cancer. Methods: Five HDR tandem and ovoid patients were planned using the Brachyvision treatment planning system and treated in four fractions using the Varian Varisource afterloader (Varian Medical Systems). For the same cohort, the patient planning CTs were imported into Multiplan (Accuray Inc) and a dose/fractionation-equivalent CyberKnife SBRT plan was retrospectively generated. Dosimetric quantities such as target/CTV D90, V90, D2cc for rectum, bladder, and bowel were measured and compared between the two modalities. Results: The CTV D90 for the tandem and ovoid was 2540cGy (90.7%) and 3009cGy (107.5%) for the CyberKnife plan. The D2cc for the rectum, bladder, and bowel were 1576cGy, 1641cGy, and 996cGy for the tandem and ovoid and 1374cGy, 1564cGy, and 1547cGy for CyberKnife. Conclusion: The D2cc doses to critical structures are comparable in both modalities. The CTV coverage is far superior for the CyberKnife plan. The dose distribution for CyberKnife has the advantage of increased conformality and lower maximum CTV dose.« less

  9. Book Club Plus: A Conceptual Framework To Organize Literacy Instruction.

    ERIC Educational Resources Information Center

    Raphael, Taffy E.; Florio-Ruane, Susan; George, MariAnne

    2001-01-01

    Notes that finding time for skills instruction without replacing literature discussion and writers' workshop requires a strong organizational framework for literacy instruction. Suggests that teachers need principled, conceptual frameworks to guide their thoughts and actions. Describes a framework, Book Club Plus, designed by a practitioner…

  10. Highway Maintenance Equipment Operator. Miscellaneous Equipment. Training Materials.

    ERIC Educational Resources Information Center

    Perky, Sandra Dutreau; And Others

    This curriculum guide provides instructional materials to assist in training equipment operators in the safe and effective use of highway maintenance equipment. It includes six units of instruction covering the small, specialized equipment used in maintenance operations. Each unit of instruction consists of eight basic components: performance…

  11. Softball: Special Olympics Sports Skills Instructional Program.

    ERIC Educational Resources Information Center

    Special Olympics, Inc., Washington, DC.

    One of seven instructional units on Special Olympics Sports Skills Instructional Programs, this guide presents suggestions for coaching softball for mentally retarded persons. An overview section provides information on teaching suggestions, followed by a list of program goals, objectives, and benefits. Sports skill assessments measure athletes'…

  12. Designing Effective Curricula with an Interactive Collaborative Curriculum Design Tool (CCDT)

    ERIC Educational Resources Information Center

    Khadimally, Seda

    2015-01-01

    Guided by the principles of the Analysis, Design, Development, Implementation, and Evaluation (ADDIE) instructional design (ID) model, this creative instructional product presents a learning/teaching approach that is fundamentally constructivist. For the purposes of designing effective instruction in an academic preparation course, a…

  13. Basketball: Special Olympics Sports Skills Instructional Program.

    ERIC Educational Resources Information Center

    Special Olympics, Inc., Washington, DC.

    One of a series of coaching guides for Special Olympics Sports Skills Instructional Programs, this booklet focuses on basketball instruction for mentally retarded persons. An initial section introduces the sport and discusses general coaching ideas. Goals, objectives, and benefits are listed along with information on clothing and court…

  14. Snowmobile Repair.

    ERIC Educational Resources Information Center

    Helbling, Wayne

    This guide is designed to provide and/or improve instruction for occupational training in the area of snowmobile repair, and includes eight areas. Each area consists of one or more units of instruction, with each instructional unit including some or all of the following basic components: Performance objectives, suggested activities for teacher and…

  15. Blended Instruction: Integrating the Curriculum through Projects and Curriculum Alignment.

    ERIC Educational Resources Information Center

    Maryland State Dept. of Education, Baltimore. Div. of Career Technology and Adult Learning.

    "Blended instruction" is an approach to integrating high school curriculum around broad career clusters or areas of student interest and study. Blended instruction is intended to engage students in more challenging assignments, increase attendance, and increase student academic and technical achievement. This Maryland guide contains…

  16. An Instructional Design Framework for Fostering Student Engagement in Online Learning Environments

    ERIC Educational Resources Information Center

    Czerkawski, Betul C.; Lyman, Eugene W.

    2016-01-01

    Many approaches, models and frameworks exist when designing quality online learning environments. These approaches assist and guide instructional designers through the process of analysis, design, development, implementation and evaluation of instructional processes. Some of these frameworks are concerned with student participation, some with…

  17. Intelligent Frameworks for Instructional Design.

    ERIC Educational Resources Information Center

    Spector, J. Michael; And Others

    Many researchers are attempting to develop automated instructional development systems to guide subject matter experts through the lengthy and difficult process of courseware development. Because the targeted users often lack instructional design expertise, a great deal of emphasis has been placed on the use of artificial intelligence (AI) to…

  18. Vocabulary Instruction: Research to Practice. Second Edition

    ERIC Educational Resources Information Center

    Kame'enui, Edward J., Ed.; Baumann, James F., Ed.

    2012-01-01

    This highly regarded work brings together prominent authorities on vocabulary teaching and learning to provide a comprehensive yet concise guide to effective instruction. The book showcases practical ways to teach specific vocabulary words and word-learning strategies and create engaging, word-rich classrooms. Instructional activities and games…

  19. Impact of Technology on the Family. Teacher Edition.

    ERIC Educational Resources Information Center

    Mid-America Vocational Curriculum Consortium, Stillwater, OK.

    These instructional materials create an awareness of new technological innovations and how they affect personal and family life. This teacher's guide is for instructing secondary students enrolled in a home economics program. The following introductory information is included: use of this publication, competency profile, instructional/task…

  20. An Automated Approach to Instructional Design Guidance.

    ERIC Educational Resources Information Center

    Spector, J. Michael; And Others

    This paper describes the Guided Approach to Instructional Design Advising (GAIDA), an automated instructional design tool that incorporates techniques of artificial intelligence. GAIDA was developed by the U.S. Air Force Armstrong Laboratory to facilitate the planning and production of interactive courseware and computer-based training materials.…

  1. SU-E-T-365: Dosimetric Impact of Dental Amalgam CT Image Artifacts On IMRT and VMAT Head and Neck Plans

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cao, N; Young, L; Parvathaneni, U

    Purpose: The presence of high density dental amalgam in patient CT image data sets causes dose calculation errors for head and neck (HN) treatment planning. This study assesses and compares dosimetric variations in IMRT and VMAT treatment plans due to dental artifacts. Methods: Sixteen HN patients with similar treatment sites (oropharynx), tumor volume and extensive dental artifacts were divided into two groups: IMRT (n=8, 6 to 9 beams) and VMAT (n=8, 2 arcs with 352° rotation). All cases were planned with the Pinnacle 9.2 treatment planning software using the collapsed cone convolution superposition algorithm and a range of prescription dosemore » from 60 to 72Gy. Two different treatment plans were produced, each based on one of two image sets: (a)uncorrected; (b)dental artifacts density overridden (set to 1.0g/cm{sup 3}). Differences between the two treatment plans for each of the IMRT and VMAT techniques were quantified by the following dosimetric parameters: maximum point dose, maximum spinal cord and brainstem dose, mean left and right parotid dose, and PTV coverage (V95%Rx). Average differences generated for these dosimetric parameters were compared between IMRT and VMAT plans. Results: The average absolute dose differences (plan a minus plan b) for the VMAT and IMRT techniques, respectively, caused by dental artifacts were: 2.2±3.3cGy vs. 37.6±57.5cGy (maximum point dose, P=0.15); 1.2±0.9cGy vs. 7.9±6.7cGy (maximum spinal cord dose, P=0.026); 2.2±2.4cGy vs. 12.1±13.0cGy (maximum brainstem dose, P=0.077); 0.9±1.1cGy vs. 4.1±3.5cGy (mean left parotid dose, P=0.038); 0.9±0.8cGy vs. 7.8±11.9cGy (mean right parotid dose, P=0.136); 0.021%±0.014% vs. 0.803%±1.44% (PTV coverage, P=0.17). Conclusion: For the HN plans studied, dental artifacts demonstrated a greater dose calculation error for IMRT plans compared to VMAT plans. Rotational arcs appear on the average to compensate dose calculation errors induced by dental artifacts. Thus, compared to VMAT, density overrides for dental artifacts are more important when planning IMRT of HN.« less

  2. Past Research in Instructional Technology: Results of a Content Analysis of Empirical Studies Published in Three Prominent Instructional Technology Journals from the Year 2000 through 2004

    ERIC Educational Resources Information Center

    Hew, Khe Foon; Kale, Ugur; Kim, Nari

    2007-01-01

    This article reviews and categorizes empirical studies related to instructional technology that were published in three prominent journals: "Educational Technology Research and Development, Instructional Science," and the "Journal of Educational Computing Research" from the year 2000 through 2004. Four questions guided this review: 1) What…

  3. Professional Development to Differentiate Kindergarten Tier 1 Instruction: Can Already Effective Teachers Improve Student Outcomes by Differentiating Tier 1 Instruction?

    ERIC Educational Resources Information Center

    Al Otaiba, Stephanie; Folsom, Jessica S.; Wanzek, Jeanne; Greulich, Luana; Waesche, Jessica; Schatschneider, Christopher; Connor, Carol M.

    2016-01-01

    Two primary purposes guided this quasi-experimental within-teacher study: (a) to examine changes from baseline through 2 years of professional development (Individualizing Student Instruction) in kindergarten teachers' differentiation of Tier 1 literacy instruction; and (b) to examine changes in reading and vocabulary of 3 cohorts of the teachers'…

  4. Instructional Coaches and the Instructional Leadership Team: A Guide for School-Building Improvement

    ERIC Educational Resources Information Center

    Spaulding, Dean T.; Smith, Gail

    2012-01-01

    For instructional coaches, no two days are ever the same. This unique companion melds theory and practice to show how coaches can seamlessly integrate themselves into the fabric of the school and help teachers improve their practice from day one. Dean Spaulding and Gail Smith address common challenges of coaches and instructional leadership teams,…

  5. New Jersey Industrial Arts Education Safety Guide.

    ERIC Educational Resources Information Center

    Kobylarz, Joseph D.; Olender, Francis B.

    This guide was developed to assist the teacher in planning, implementing, revising, or improving safety instruction in industrial arts classes in New Jersey, and has as its theme, "Safety Is Everyone's Responsibility." The guide is organized in seven major sections. The first section explains the purpose of the guide, outlines the…

  6. Oxidative Stress and Skeletal Health with Low-Dose, Low-LET (Linear Energy Transfer) Ionizing Radiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Globus, Ruth K.

    We performed in vivo and in vitro experiments to accomplish the following specific aims of this project: 1) determine if low dose, low LET radiation affects skeletal remodeling at structural, cellular and molecular levels and 2) determine if low dose, low LET radiation modulates skeletal health during aging via oxidative mechanisms. A third aim is supported by NASA supplement to this DOE grant focusing on the influence of high LET radiation on bone. A series of experiments were conducted at the NASA Space Radiation Laboratory at Brookhaven, NSRL-BNL, using iron (56Fe) or a sequential exposure to protons / iron /more » protons, and separate experiments at NASA Ames Research Center (ARC) using 137Cs. The following provides a summary of key findings. (1) Exposure of nine-week old female mice to priming doses of gamma radiation (10cGy x 5) did not significantly affect bone volume/total volume (BV/TV) or microarchitecture as analyzed by 3D microcomputed tomography. As expected, exposure to the challenge dose of 2 Gy gamma irradiation resulted in significant decreases in BV/TV. The priming dose combined with the 2Gy challenge dose had no further effect on BV/TV compared to challenge dose alone, with the sole exception of the Structural Model Index (SMI). SMI reflects the ratio of rods-to-plates in cancellous bone tissue, such that higher SMI values indicate a tendency toward a weaker structure compared to lower SMI values. Mice treated with both priming and challenge dose had 25% higher SMI values compared to sham-irradiated controls and 7% higher values compared to mice treated with the challenge dose alone. Thus, although this priming regimen had relatively modest effects on cancellous tissue, the difference in SMI suggests this fractionated priming doses have adverse, rather than beneficial, effects on bone structure. (2) In 10-week old male mice, a single exposure to 100cGy of 137Cs reduces trabecular bone number and connectivity density by 20% and 36% respectively one month after irradiation (IR). At four months post-IR, these animals were comparable to sham-treated controls with regards to the abovementioned structural parameters. Irradation at 1 or 10 cGy did not result in any significant changes in bone structural parameters. (3) Irradiation of 16-wk old male mice with high doses of 56Fe or proton (50 or 200cGy), but not at low doses (5 or 10cGy), showed a similar loss of cancellous BV/TV and trabecular number at five weeks post-IR. (4) Age-related bone loss overtook acute radiation-induced decrements in bone structure within four months post-IR with 100 cGy gamma and 12 months post-IR with 200 cGy iron. Transgenic mice globally overexpressing human catalase gene in mitochondria did not exhibit cancellous bone loss as assessed at four month post-IR with 10 cGy proton, 50 cGy iron, or in combination. (5) The cellular and molecular mechanisms responsible for loss of bone with radiation are mediated primarily through increased osteoclastogenesis. Our data provide evidence that there are increases in gene expression of TNF alpha and MCP1 in the bone marrow cells 24 hours post-IR and of osteoclastogenic differentiation factor RANKL by day 3. These cytokines in the marrow may stimulate mature osteoclasts or drive osteoclastogenesis from precursors. (6) Osteoblastogenesis from marrow progenitors evaluated ex vivo decreased following whole body 56Fe irradiation at a dose threshold between 20 and 50 cGy whereas osteoclastogenesis ex vivo increased with doses as low as 10cGy two days post-IR of mice. However, the latter finding was not observed in more than a single experiment. (7) Gamma irradiation of cells in vitro requires relatively high doses (200cGy) to disturb normal osteoblastogenesis and osteoclastogenesis as evidenced by decrements in mineralized nodule formation, osteoclast counts, and expression of osteoblast related genes such as runx2, col1a1. (8) We also investigated the effect of antioxidants on osteoblastogenesis following low dose in vitro gamma irradiation (15cGy) on day four bone marrow stromal cell cultures. Superoxide dismutase (SOD) was added to the cell culture medium for 2 or 3 days post-irradiation and cell colonies were counted on days 7 and 10. SOD treatment increased cell growth as measured by DNA content and colony forming units (CFU) in both irradiated cells and 0 cGy control groups. However, low dose radiation of 15cGy abolished SOD stimulatory effects on cell growth and CFU number. These results suggest that exogenous SOD increases osteoblast cell growth and colony formation and that low-dose radiation (15cGy) can interfere with the antioxidant effects. In summary, our findings indicate that acute, whole body irradiation at high doses (50-200 cGy) results in prompt tissue degradation and bone loss. Lower doses (<50 cGy) do not cause bone structural deterioration but may deplete stem/progenitor cell pools in the bone marrow.« less

  7. Highway Maintenance Equipment Operator. Specialized Equipment. Training Materials.

    ERIC Educational Resources Information Center

    Perky, Sandra Dutreau; And Others

    This curriculum guide provides instructional materials to assist in training equipment operators in the safe and effective use of highway maintenance equipment. It includes 18 units of instruction covering the large equipment used in maintenance operations. Each unit of instruction consists of eight basic components: performance objectives,…

  8. Targeted Observation of ELL Instruction as a Tool in the Preparation of School Leaders

    ERIC Educational Resources Information Center

    Baecher, Laura; Knoll, Marcia; Patti, Janet

    2016-01-01

    Preparing school administrators to promote effective instruction of English language learners (ELLs) is an important dimension of today's educational leadership programs, requiring innovative program activities. This study explores school leadership candidates' use of an observation tool targeted to ELL instruction that incorporated guided video…

  9. A Guide to Instructional Resources for Consumers' Education.

    ERIC Educational Resources Information Center

    Johnston, William L.; Greenspan, Nancy B.

    This annotated bibliography lists 295 selected instructional references, resources, and teaching aids for consumer education. It includes a variety of both print and nonprint materials, such as films, filmstrips, multimedia kits, games and learning packages for classroom and group instruction, textbooks for all age levels, and references for both…

  10. Exploring the Past and Connecting the Present: One Latina Teacher's Story.

    ERIC Educational Resources Information Center

    Walker, Nancy T.

    This study investigated the relationships between teachers' education and their instructional style, focusing on one Latina elementary teacher working with English language learners. It examined what beliefs guided her choice of literacy instruction, how school structure impacted instruction, and the roles of culture and gender in literacy…

  11. The ABE/AMH Manual. An Instructional Guide for ABE Programs Serving Mentally Handicapped Adults.

    ERIC Educational Resources Information Center

    Lehman, Scott C.; Edgar, S. Keith

    This handbook provides adult basic education teachers with instructional materials for working with adult mentally handicapped students. Section 1 examines planning programs for adult mentally retarded students (getting started, specific considerations, various kinds of program sites) and implementing instruction (staff selection and training).…

  12. Program of Studies. Instructional Goals and Objectives: Art.

    ERIC Educational Resources Information Center

    West Virginia State Dept. of Education, Charleston.

    Instructional goals and sample instructional objectives for art education in West Virginia's public schools are outlined. A comprehensive arts education program is basic to the general education of every child. Two guiding principles directed the programs' design. First, each student should have opportunities to acquire skills in the four…

  13. Sustaining Innovation: Developing an Instructional Technology Assessment Process

    ERIC Educational Resources Information Center

    Carmo, Monica Cristina

    2013-01-01

    This case study developed an instructional technology assessment process for the Gevirtz Graduate School of Education (GGSE). The theoretical framework of Adelman and Taylor (2001) guided the development of this instructional technology assessment process and the tools to aid in its facilitation. GGSE faculty, staff, and graduate students…

  14. Two-Year Core Curriculum for Agricultural Education in Montana. Revised.

    ERIC Educational Resources Information Center

    Montana State Univ., Bozeman. Dept. of Agricultural and Industrial Education.

    This guide contains suggested units of instruction for the first two years of instruction in secondary vocational agriculture. It is intended to aid teachers and administrators in planning instructional programs to equip students with essential basic competencies required for more specialized programs. Instructor materials include information on…

  15. Fiber, Fabric, and Fashion. Environment III.

    ERIC Educational Resources Information Center

    Arizona State Univ., Tempe.

    A competency-based instructional guide for grades 7-14, this volume is one of three parts, each of which focuses on a different environment (psychomotor, cognitive, or affective) for clothing and fashion instruction, and each of which includes competencies and corresponding learning activities for each of three instructional levels. The topic for…

  16. Applications of Oral Proficiency Testing to Foreign Language. Instruction.

    ERIC Educational Resources Information Center

    American Council on the Teaching of Foreign Languages, Hastings-on-Hudson, NY.

    A guide to the adaptation of oral proficiency testing for classroom language instruction contains excerpts of projects by participants in an American Council on the Teaching of Foreign Languages (ACTFL) workshop. The excerpts are examples of proficiency based curricula and materials designed to personalize instruction and simulate real-life…

  17. Designing Adaptive Instruction for Teams: A Meta-Analysis

    ERIC Educational Resources Information Center

    Sottilare, Robert A.; Shawn Burke, C.; Salas, Eduardo; Sinatra, Anne M.; Johnston, Joan H.; Gilbert, Stephen B.

    2018-01-01

    The goal of this research was the development of a practical architecture for the computer-based tutoring of teams. This article examines the relationship of team behaviors as antecedents to successful team performance and learning during adaptive instruction guided by Intelligent Tutoring Systems (ITSs). Adaptive instruction is a training or…

  18. Creating Shared Instructional Products: An Alternative Approach to Improving Teaching

    ERIC Educational Resources Information Center

    Morris, Anne K.; Hiebert, James

    2011-01-01

    To solve two enduring problems in education--unacceptably large variation in learning opportunities for students across classrooms and little continuing improvement in the quality of instruction--the authors propose a system that centers on the creation of shared instructional products that guide classroom teaching. By examining systems outside…

  19. Sonoma Developmental Curriculum: Instructional Programs. Volume II.

    ERIC Educational Resources Information Center

    Adams, Patrick, Ed.; And Others

    The guide presents instructional materials for teaching developmentally delayed children from birth to 6 years old. The following five instructional areas are covered (with sample activities in parentheses): gross motor (demonstrates a tonic-neck reflex, demonstrates ability to bear almost full weight, and crawls backward down three steps); fine…

  20. Classroom Instruction That Works: Research-Based Strategies for Increasing Student Achievement. Second Edition

    ERIC Educational Resources Information Center

    Dean, Ceri B.; Stone, BJ; Hubbell, Elizabeth; Pitler, Howard

    2012-01-01

    First published in 2001, "Classroom Instruction That Works" revolutionized teaching by linking classroom strategies to evidence of increased student learning. Now this landmark guide has been reenergized and reorganized for today's classroom with new evidence-based insights and a refined framework that strengthens instructional planning. Whether…

  1. Cooperative learning in third graders' jigsaw groups for mathematics and science with and without questioning training.

    PubMed

    Souvignier, Elmar; Kronenberger, Julia

    2007-12-01

    There is much support for using cooperative methods, since important instructional aspects, such as elaboration of new information, can easily be realized by methods like 'jigsaw'. However, the impact of providing students with additional help like a questioning training and potential limitations of the method concerning the (minimum) age of the students have rarely been investigated. The study investigated the effects of cooperative methods at elementary school level. Three conditions of instruction were compared: jigsaw, jigsaw with a supplementary questioning training and teacher-guided instruction. Nine third grade classes from three schools with 208 students participated in the study. In each school, all the three instructional conditions were realized in three different classes. All classes studied three units on geometry and one unit on astronomy using the assigned instructional method. Each learning unit comprised six lessons. For each unit, an achievement test was administered as pre-test, post-test and delayed test. In the math units, no differences between the three conditions could be detected. In the astronomy unit, students benefited more from teacher-guided instruction. Differential analyses revealed that 'experts' learned more than students in teacher-guided instruction, whereas 'novices' were outperformed by the students in the control classes. Even third graders used the jigsaw method with satisfactory learning results. The modest impact of the questioning training and the low learning gains of the cooperative classes in the astronomy unit as well as high discrepancies between learning outcomes of experts and novices show that explicit instruction of explaining skills in combination with well-structured material are key issues in using the jigsaw method with younger students.

  2. Equasions for Curriculum Improvement.

    ERIC Educational Resources Information Center

    Eckenrod, James S.

    1986-01-01

    Describes the Technology in Curriculum (TIC) program resource guides which will be distributed to California schools in the fall of 1986. These guides match available instructional television programs and computer software to existing California curriculum guides in order to facilitate teachers' classroom use. (JDH)

  3. Teachers' Guide for Aviation Education for Use in Grades Two through Six.

    ERIC Educational Resources Information Center

    Aviation/Space, 1979

    1979-01-01

    This teacher's guide provides supplementary activities in aviation designed for students in grades 2-6. The activities stress communication arts, science, and social studies. The guide contains performance objectives, instructional procedures, student activities, and outcomes. (MA)

  4. UIAGM Ropehandling Techniques.

    ERIC Educational Resources Information Center

    Cloutier, K. Ross

    The Union Internationale des Associations des Guides de Montagne's (UIAGM) rope handling techniques are intended to form the standard for guiding ropework worldwide. These techniques have become the legal standard for instructional institutions and commercial guiding organizations in UIAGM member countries: Austria, Canada, France, Germany, Great…

  5. See Also:physica status solidi (a)physica status solidi (c)Copyright © 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

  6. Get Sample Copy
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  1. Managing the Office Environment. Instructor's Guide. Student Activity Packet. Office Occupations.

    ERIC Educational Resources Information Center

    Johnson, Diane E.

    This training package, one in a series of instructional modules consisting of an instructor's guide and a student activity packet, deals with managing the office environment. Included in the instructor's guide are general directions for implementing the presentation; a detailed guide for teaching the lesson that includes performance objectives,…

  2. Communication and Industrial Electronics. Trade and Industrial Education Trade Preparatory Training Guide.

    ERIC Educational Resources Information Center

    Nebraska State Dept. of Education, Lincoln. Div. of Vocational Education.

    One of a series of curriculum guides prepared for the electricity/electronics occupations cluster, this guide identifies the essentials of the communication and industrial electronics trade as recommended by the successful electrical servicemen. An instructional program based upon the implementation of the guide is expected to prepare a student to…

  3. Leveraging the Libguides Platform for Electronic Resources Access Assistance

    ERIC Educational Resources Information Center

    Erb, Rachel A.; Erb, Brian

    2014-01-01

    This case study offers an alternative use of LibGuides beyond its intended purpose to offer course and subject guides. LibGuides have become an integral part of the virtual instruction landscape at Colorado State University (CSU) Libraries. We discovered that the LibGuides platform can also be effectively harnessed to provide support for…

  4. Career Orientation. Arkansas Public School Course Content Guide.

    ERIC Educational Resources Information Center

    Arkansas State Dept. of Education, Little Rock.

    This course content guide was developed in accordance with the Standards for Accreditation of Public Schools adopted by the Arkansas State Board of Education. The guide is offered as a framework upon which a curriculum can be built. The content guide identifies skills at three instructional levels: basic, developmental, and extensions. The basic…

  5. Home Economics. Arkansas Public School Course Content Guide.

    ERIC Educational Resources Information Center

    Arkansas State Dept. of Education, Little Rock.

    This course content guide was developed in accordance with the Standards for Accreditation of Public Schools adopted by the Arkansas State Board of Education. The guide is offered as a framework upon which a curriculum can be built. Within each subject area, the content guide identifies skills at three instructional levels: basic, developmental,…

  6. Masonry. Trade and Industrial Education Trade Preparatory Training Guide.

    ERIC Educational Resources Information Center

    Nebraska State Dept. of Education, Lincoln. Div. of Vocational Education.

    One of a series of curriculum guides prepared for the building occupations cluster of the construction/fabrication occupational group, this guide identifies the essentials of the masonry trade as recommended by the successful mason. An instructional program based upon the implementation of the guide is expected to prepare a student to adequately…

  7. Leader's Guide: Facilitating Inquiry in the Classroom.

    ERIC Educational Resources Information Center

    Newton, Fred E.

    This is the leader's guide and training materials for conducting workshops on an instructional system which utilizes the process of inquiry. The guide is designed for leaders of these workshops and lists the leader's activities. It is organized according to the 18 major workshop experiences, referred to as subset. Each subset guide is organized…

  8. Graphic Arts. Trade and Industrial Education Trade Preparatory Training Guide.

    ERIC Educational Resources Information Center

    Nebraska State Dept. of Education, Lincoln. Div. of Vocational Education.

    One of a series of curriculum guides prepared for the graphic communications occupations cluster, this guide identifies the essentials of the graphic arts trade as recommended by the successful printers. An instructional program based upon the implementation of the guide is expected to prepare a student to adequately perform entry level tasks…

  9. Welding and Cutting. Trade and Industrial Education Trade Preparatory Training Guide.

    ERIC Educational Resources Information Center

    Nebraska State Dept. of Education, Lincoln. Div. of Vocational Education.

    One of a series of curriculum guides prepared for the metals occupations cluster of the construction/fabrication occupational group, this guide identifies the essentials of the welding and cutting trade as recommended by successful welders. An instructional program based upon the implementation of the guide is expected to prepare a student to…

  10. Health Occupations. Arkansas Public School Course Content Guide.

    ERIC Educational Resources Information Center

    Arkansas State Dept. of Education, Little Rock.

    This course content guide was developed in accordance with the Standards for Accreditation of Public Schools adopted by the Arkansas State Board of Education. The guide is offered as a framework upon which a curriculum can be built. Within each subject area the content guide identifies skills at three instructional levels: basic, developmental,…

  11. Guiding Principles for Student Leadership Development in the Doctor of Pharmacy Program to Assist Administrators and Faculty Members in Implementing or Refining Curricula

    PubMed Central

    Boyle, Cynthia J.; Janke, Kristin K.

    2013-01-01

    Objective. To assist administrators and faculty members in colleges and schools of pharmacy by gathering expert opinion to frame, direct, and support investments in student leadership development. Methods. Twenty-six leadership instructors participated in a 3-round, online, modified Delphi process to define doctor of pharmacy (PharmD) student leadership instruction. Round 1 asked open-ended questions about leadership knowledge, skills, and attitudes to begin the generation of student leadership development guiding principles and competencies. Statements were identified as guiding principles when they were perceived as foundational to the instructional approach. Round 2 grouped responses for agreement rating and comment. Group consensus with a statement as a guiding principle was set prospectively at 80%. Round 3 allowed rating and comment on guidelines, modified from feedback in round 2, that did not meet consensus. The principles were verified by identifying common contemporary leadership development approaches in the literature. Results. Twelve guiding principles, related to concepts of leadership and educational philosophy, were defined and could be linked to contemporary leadership development thought. These guiding principles describe the motivation for teaching leadership, the fundamental precepts of student leadership development, and the core tenets for leadership instruction. Conclusions. Expert opinion gathered using a Delphi process resulted in guiding principles that help to address many of the fundamental questions that arise when implementing or refining leadership curricula. The principles identified are supported by common contemporary leadership development thought. PMID:24371345

  12. Guiding principles for student leadership development in the doctor of pharmacy program to assist administrators and faculty members in implementing or refining curricula.

    PubMed

    Traynor, Andrew P; Boyle, Cynthia J; Janke, Kristin K

    2013-12-16

    To assist administrators and faculty members in colleges and schools of pharmacy by gathering expert opinion to frame, direct, and support investments in student leadership development. Twenty-six leadership instructors participated in a 3-round, online, modified Delphi process to define doctor of pharmacy (PharmD) student leadership instruction. Round 1 asked open-ended questions about leadership knowledge, skills, and attitudes to begin the generation of student leadership development guiding principles and competencies. Statements were identified as guiding principles when they were perceived as foundational to the instructional approach. Round 2 grouped responses for agreement rating and comment. Group consensus with a statement as a guiding principle was set prospectively at 80%. Round 3 allowed rating and comment on guidelines, modified from feedback in round 2, that did not meet consensus. The principles were verified by identifying common contemporary leadership development approaches in the literature. Twelve guiding principles, related to concepts of leadership and educational philosophy, were defined and could be linked to contemporary leadership development thought. These guiding principles describe the motivation for teaching leadership, the fundamental precepts of student leadership development, and the core tenets for leadership instruction. Expert opinion gathered using a Delphi process resulted in guiding principles that help to address many of the fundamental questions that arise when implementing or refining leadership curricula. The principles identified are supported by common contemporary leadership development thought.

  13. Clinical relevance of findings in trials of CBT for depression.

    PubMed

    Lepping, P; Whittington, R; Sambhi, R S; Lane, S; Poole, R; Leucht, S; Cuijpers, P; McCabe, R; Waheed, W

    2017-09-01

    Cognitive behavioural therapy (CBT) is beneficial in depression. Symptom scores can be translated into Clinical Global Impression (CGI) scale scores to indicate clinical relevance. We aimed to assess the clinical relevance of findings of randomised controlled trials (RCTs) of CBT in depression. We identified RCTs of CBT that used the Hamilton Rating Scale for Depression (HAMD). HAMD scores were translated into Clinical Global Impression - Change scale (CGI-I) scores to measure clinical relevance. One hundred and seventy datasets from 82 studies were included. The mean percentage HAMD change for treatment arms was 53.66%, and 29.81% for control arms, a statistically significant difference. Combined active therapies showed the biggest improvement on CGI-I score, followed by CBT alone. All active treatments had better than expected HAMD percentage reduction and CGI-I scores. CBT has a clinically relevant effect in depression, with a notional CGI-I score of 2.2, indicating a significant clinical response. The non-specific or placebo effect of being in a psychotherapy trial was a 29% reduction of HAMD. Copyright © 2017. Published by Elsevier Masson SAS.

  14. Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis.

    PubMed

    Di Paolo, Julie A; Huang, Tao; Balazs, Mercedesz; Barbosa, James; Barck, Kai H; Bravo, Brandon J; Carano, Richard A D; Darrow, James; Davies, Douglas R; DeForge, Laura E; Diehl, Lauri; Ferrando, Ronald; Gallion, Steven L; Giannetti, Anthony M; Gribling, Peter; Hurez, Vincent; Hymowitz, Sarah G; Jones, Randall; Kropf, Jeffrey E; Lee, Wyne P; Maciejewski, Patricia M; Mitchell, Scott A; Rong, Hong; Staker, Bart L; Whitney, J Andrew; Yeh, Sherry; Young, Wendy B; Yu, Christine; Zhang, Juan; Reif, Karin; Currie, Kevin S

    2011-01-01

    Bruton's tyrosine kinase (Btk) is a therapeutic target for rheumatoid arthritis, but the cellular and molecular mechanisms by which Btk mediates inflammation are poorly understood. Here we describe the discovery of CGI1746, a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation. Using CGI1746, we demonstrate that Btk regulates inflammatory arthritis by two distinct mechanisms. CGI1746 blocks B cell receptor-dependent B cell proliferation and in prophylactic regimens reduces autoantibody levels in collagen-induced arthritis. In macrophages, Btk inhibition abolishes FcγRIII-induced TNFα, IL-1β and IL-6 production. Accordingly, in myeloid- and FcγR-dependent autoantibody-induced arthritis, CGI1746 decreases cytokine levels within joints and ameliorates disease. These results provide new understanding of the function of Btk in both B cell- or myeloid cell-driven disease processes and provide a compelling rationale for targeting Btk in rheumatoid arthritis.

  15. Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Di Paolo, Julie A; Huang, Tao; Balazs, Mercedesz

    Bruton's tyrosine kinase (Btk) is a therapeutic target for rheumatoid arthritis, but the cellular and molecular mechanisms by which Btk mediates inflammation are poorly understood. Here we describe the discovery of CGI1746, a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation. Using CGI1746, we demonstrate that Btk regulates inflammatory arthritis by two distinct mechanisms. CGI1746 blocks B cell receptor–dependent B cell proliferation and in prophylactic regimens reduces autoantibody levels in collagen-induced arthritis. In macrophages, Btkmore » inhibition abolishes FcγRIII-induced TNFα, IL-1β and IL-6 production. Accordingly, in myeloid- and FcγR-dependent autoantibody-induced arthritis, CGI1746 decreases cytokine levels within joints and ameliorates disease. These results provide new understanding of the function of Btk in both B cell– or myeloid cell–driven disease processes and provide a compelling rationale for targeting Btk in rheumatoid arthritis.« less

  16. Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Di Paolo, Julie A.; Huang, Tao; Balazs, Mercedesz

    Bruton's tyrosine kinase (Btk) is a therapeutic target for rheumatoid arthritis, but the cellular and molecular mechanisms by which Btk mediates inflammation are poorly understood. Here we describe the discovery of CGI1746, a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation. Using CGI1746, we demonstrate that Btk regulates inflammatory arthritis by two distinct mechanisms. CGI1746 blocks B cell receptor-dependent B cell proliferation and in prophylactic regimens reduces autoantibody levels in collagen-induced arthritis. In macrophages, Btkmore » inhibition abolishes Fc{gamma}RIII-induced TNF{alpha}, IL-1{beta} and IL-6 production. Accordingly, in myeloid- and Fc{gamma}R-dependent autoantibody-induced arthritis, CGI1746 decreases cytokine levels within joints and ameliorates disease. These results provide new understanding of the function of Btk in both B cell- or myeloid cell-driven disease processes and provide a compelling rationale for targeting Btk in rheumatoid arthritis.« less

  17. Training for Certification: Trainer's Guide.

    ERIC Educational Resources Information Center

    Mississippi State Univ., State College. Cooperative Extension Service.

    This Cooperative Extension Service publication from Mississippi State University is a teacher's guide for a private pesticide applicator certification training program. This guide is designed for use by county extension agents. Contents include: (1) a suggested training schedule; (2) stepwise instructions for implementation of the private…

  18. [Mathematics in the Out Doors].

    ERIC Educational Resources Information Center

    Barcomb, Francois; And Others

    Designed for the instruction of emotionally handicapped children and youth, this guide presents mathematical concepts and activities which may be utilized in outdoor education. Three authors provide three individualized resource guides on mathematics; Guide 1 deals with the concepts of measurement, time, estimation, geometry, counting, and…

  19. Marketing Education Curriculum Guide.

    ERIC Educational Resources Information Center

    Michigan State Univ., East Lansing. Coll. of Agriculture and Natural Resources Education Inst.

    This curriculum guide is intended to provide a common core of competencies from which to design an effective secondary marketing education program. Introductory materials include a definition of marketing education, objectives, outline of instructional content, and questions and answers regarding the curriculum guide. These practical materials are…

  20. Drafting Lab Management Guide.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Instructional Materials Lab.

    This manual was developed to guide drafting instructors and vocational supervisors in sequencing laboratory instruction and controlling the flow of work for a 2-year machine trades training program. The first part of the guide provides information on program management (program description, safety concerns, academic issues, implementation…

  1. Micronucleus induction in Vicia faba roots. Part 2. Biological effects of neutrons below 1 cGy.

    PubMed

    Marshall, I; Bianchi, M

    1983-08-01

    A dose-effect relationship has been established for high-energy neutrons (maximum energy 600 MeV) within a dose range of 0.2 to 80 cGy and for low-energy neutrons produced by a 252Cf source (mean energy 2.35 MeV) for doses between 0.2 and 5 cGy. The frequency of micronuclei was found to increase linearly with dose. The relative biological effectiveness (r.b.e) values calculated using 60Co radiation as a reference were, in the high-dose region, 4.7 +/- 0.4 and 11.8 +/- 1.3 for the high- and low-energy neutrons, respectively. At doses below 1 cGy constant values of 25.4 +/- 4.4 and 63.7 +/- 12 were reached for the respective neutron energies.

  2. Risk factors for scoliosis in children with neuroblastoma

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Paulino, Arnold C.; Fowler, B. Zach

    2005-03-01

    Purpose: To determine the risk factors for scoliosis in children treated for neuroblastoma. Methods and materials: From 1957 to 1997, 58 children with neuroblastoma were treated at one institution and have survived a minimum of 5 years. There were 35 boys and 23 girls with a median age of 6 months (range, 2 weeks to 15 years) at initial diagnosis. Primary site was located in the adrenal gland in 25 (43.1%), abdominal/nonadrenal in 16 (27.6%), thoracic in 12 (20.7%), cervical in 3 (5.3%), and pelvic region in 2 (3.5%). The International Neuroblastoma Staging System (INSS) stage was Stage 1 inmore » 10 (17.2%), Stage 2A in 7 (12.1%), Stage 2B in 5 (8.6%), Stage 3 in 22 (37.9%), Stage 4 in 4 (6.9%), and Stage 4S in 10 (17.2%). Thirty-three (56.9%) received chemotherapy whereas 5 (8.6%) had a laminectomy as part of the surgical procedure. Twenty-seven (46.6%) received radiotherapy (RT). Beam energy was 1.25 MV in 11 (41%), 250 kV in 10 (37%), 4 MV in 4 (15%), and 6-MV photons in 1 patient. One patient received 300 cGy in 1 fraction total skin RT using 6-MeV electrons. For the remaining patients, fraction size was 100 cGy in 6 (22%), 150-180 cGy in 11 (41%), 200 cGy in 4 (15%), and 250-300 cGy in 3. Three patients had total body irradiation at 333 cGy for 3 fractions. For all children who received RT, median total dose was 2000 cGy (range, 300-3900 cGy). Patients who were treated with RT had plain films of the irradiated area every 1 to 2 years until at least the age of puberty. Median follow-up was 10 years (range, 5-46 years). Results: The overall 5-, 10-, and 15-year scoliosis-free rates were 87.6%, 79.0%, and 76.0% respectively. Twelve (21%) developed scoliosis at a median time of 51 months (range, 8-137 months). The degree of scoliosis was mild ({<=}20 deg ) in 8 (67%). Four had scoliosis ranging from 30 deg to 66 deg ; 3 of these patients required surgical intervention, whereas 1 had an underlying Duchenne muscular dystrophy which manifested itself 8 years after diagnosis of neuroblastoma. Median time to scoliosis was 23 months (range, 8-54 months) in children who had a laminectomy. On multivariate analysis, both history of laminectomy (p = 0.0005) and use of RT (p = 0.0284) were found to be risk factors for development of scoliosis. Gender, age at diagnosis, INSS stage, primary site, and use of chemotherapy were not found to be significant. Both RT fraction size and beam energy were also not significant, but increasing total RT dose was found to be significant (p = 0.0039). The 15-year scoliosis-free rates were 20% for children who had a laminectomy and 81.3% for those who did not have a laminectomy. The 15-year scoliosis-free rates for children treated with RT doses 0 cGy, 1-1750 cGy, 1751-2300 cGy, and >2300 cGy were 91.7%, 87.5%, 51.4%, and 44.4% respectively. Conclusions: Treatment-related factors, namely laminectomy and radiotherapy, were found to increase the risk of scoliosis in patients with neuroblastoma. Children who had a laminectomy were more likely to manifest scoliosis earlier. Increasing RT dose was found to impact adversely on the development of scoliosis.« less

  3. Learning to Read and Write the Drafting Way. Field Test Copy.

    ERIC Educational Resources Information Center

    California State Dept. of Education, Sacramento. Div. of Vocational Education.

    This volume comprises instructional techniques that are designed for use with drafting students who demonstrate a need for additional instruction in the areas of reading, writing, math, and verbal and visual communication. Included in the guide are the following teacher-developed instructional techniques: a drafting crossword puzzle, tool bingo, a…

  4. Automated Instructional Management Systems (AIMS) Version III, Operator's Guide.

    ERIC Educational Resources Information Center

    New York Inst. of Tech., Old Westbury.

    This manual gives the instructions necessary to understand and operate the Automated Instructional Management System (AIMS), utilizing IBM System 360, Model 30/Release 20 Disk Operating System, and the OpScan 100 System Reader and Tape Unit. It covers the AIMS III system initialization, system and operational input, requirements, master response…

  5. Orientation: Automotive Mechanics Instructional Program. Block 1.

    ERIC Educational Resources Information Center

    O'Brien, Ralph D.

    The first six instructional blocks in automotive mechanics, the lessons and supportive information in the document provide a guide for teachers in planning an instructional program in the basic theory and practice of a beginning course at the secondary and post-secondary level. The material, as organized, is a suggested sequence of instruction…

  6. Modeling Instruction in AP Physics C: Mechanics and Electricity and Magnetism

    ERIC Educational Resources Information Center

    Belcher, Nathan Tillman

    2017-01-01

    This action research study used data from multiple assessments in Mechanics and Electricity and Magnetism to determine the viability of Modeling Instruction as a pedagogy for students in AP Physics C: Mechanics and Electricity and Magnetism. Modeling Instruction is a guided-inquiry approach to teaching science in which students progress through…

  7. Effects of Developed Electronic Instructional Medium on Students' Achievement in Biology

    ERIC Educational Resources Information Center

    Chinna, Nsofor Caroline; Dada, Momoh Gabriel

    2013-01-01

    The study investigated the effects of developed electronic instructional medium (video DVD instructional package) on students' achievement in Biology. It was guided by two research questions and two hypotheses, using a quasi-experimental, pretest-postest control group design. The sample comprised of 180 senior secondary, year two students from six…

  8. Capitalizing on Curriculum-Based Measurement for Reading: Collaboration within a Response to Instruction Framework

    ERIC Educational Resources Information Center

    Weiss, Stacy L.; Friesen, Amber

    2014-01-01

    Response to Instruction (RTI) frameworks provide a structure for assessing student progress and evaluating the effectiveness of reading interventions. Schools frequently use RTI to support students who are struggling with learning to read while utilizing curriculum-based measurement (CBM) to monitor performance and guide instructional decisions…

  9. Instructional Computing. An Action Guide for Educators.

    ERIC Educational Resources Information Center

    Dennis, J. Richard; Kansky, Robert J.

    This book is directed to any educator who is interested in the use of the computer to improve classroom instruction. It is a book about the materials, human factors, and decision-making procedures that make up the instructional application of computers. This document's single goal is to promote educators' thoughtful selection and use of both…

  10. Pentagon. Civil Defense and Fire Instructions. Part 2: Shelter Management.

    ERIC Educational Resources Information Center

    Office of the Army Headquarters Commandant, Washington, DC.

    This instructional guide to civil defense shelter management is given as an aid to shelter survival techniques rather than to shelter comfort. The basis, purposes, and organization of shelter administration are outlined, with instructions on--(1) shelter management, (2) shelter teams and functions, (3) supplies and locations, and (4) daily shelter…

  11. Issues of Instructional Supervisory Practices in Primary Schools of Ebonyi State

    ERIC Educational Resources Information Center

    Onele, Adali A.; Aja-Okorie, Uzoma

    2016-01-01

    The study examines the issue of instructional supervision in primary schools of Onueke educational zone of Ebonyi state. The purpose of the study was to find out the problems militating against effective instructional supervision in the zone. Four research questions guided the study and descriptive survey research design was employed. The…

  12. Evaluating the Effectiveness of Remedial Reading Courses at Community Colleges: A Quantitative Study

    ERIC Educational Resources Information Center

    Lavonier, Nicole

    2014-01-01

    The present study evaluated the effectiveness of two instructional approaches for remedial reading courses at a community college. The instructional approaches were strategic reading and traditional, textbook-based instruction. The two research questions that guided the quantitative, quasi-experimental study were: (a) what is the effect of…

  13. A Guide to Addressing Multiple Priorities in Core Content Instruction for Students with Severe Disabilities

    ERIC Educational Resources Information Center

    Root, Jenny R.; Knight, Victoria F.; Mims, Pamela J.

    2017-01-01

    Instruction in academic core content provides students with moderate to severe disabilities a full educational opportunity that promotes current and future options in the community and can complement acquisition of daily living skills. However, high school teachers face many challenges in balancing instructional priorities given the mission to…

  14. Explicit Instruction in Core Reading Programs

    ERIC Educational Resources Information Center

    Reutzel, D. Ray; Child, Angela; Jones, Cindy D.; Clark, Sarah K.

    2014-01-01

    The purpose of this study was to conduct a content analysis of the types and occurrences of explicit instructional moves recommended for teaching five essentials of effective reading instruction in grades 1, 3, and 5 core reading program teachers' editions in five widely marketed core reading programs. Guided practice was the most frequently…

  15. Cooperative Driver Education and Safety Training. Instructor's Guide.

    ERIC Educational Resources Information Center

    Seyfarth, John T.; And Others

    The program, designed to give the driver-training pupil a semester of 50 hours of instruction, involves four instructional phases, one of them optional to give flexibility to fit the varying needs of different school systems: Phase 1--the classroom phase, with 30 instructional hours devoted to 30 specific events, staggered at each school…

  16. Guiding Blind Pedestrians with a Personal Navigation System

    NASA Astrophysics Data System (ADS)

    Dodson, A. H.; Moon, G. V.; Moore, T.; Jones, D.

    With the assistance provided by the white cane or guide dog, most blind pedestrians can find their way to known destinations along familiar routes. Finding new or known destinations along unfamiliar routes is more challenging. Before such a journey is attempted, detailed instructions must be acquired. The difficulty of obtaining and then reliably following such instructions deters many blind pedestrians from travelling alone in unknown areas. This paper demonstrates a technological approach, by way of field trials, that supplements the existing aids and eliminates the need for sighted guides. The approach has the potential to offer greater independence to the blind person. The investigation suggests that the methodology used in personal navigation systems for the sighted is sub-optimal for guiding the blind pedestrian. Suitable extensions are introduced, and the results show the proposed methodology is efficient for guiding the blind individual to unknown destinations in the chosen field trial environment.

  17. Current science requirements and planned implementation for the WFIRST-CGI Integral Field Spectrograph (IFS)

    NASA Astrophysics Data System (ADS)

    Mandell, Avi M.; Groff, Tyler D.; Gong, Qian; Rizzo, Maxime J.; Lupu, Roxana; Zimmerman, Neil T.; Saxena, Prabal; McElwain, Michael W.

    2017-09-01

    One of the key science goals of the Coronograph Instrument (CGI) on the WFIRST mission is to spectrally characterize the atmospheres of planets around other stars at extremely high contrast levels. To achieve this goal, the CGI instrument will include a integral field spectrograph (IFS) as one of the two science cameras. We present the current science requirements that pertain to the IFS design, describe how our design implementation flows from these requirements, and outline our current instrument design.

  18. Current Science Requirements and Planned Implementation for the WFIRST-CGI Integral Field Spectrograph (IFS)

    NASA Technical Reports Server (NTRS)

    Mandell, Avi M.; Groff, Tyler D.; Gong, Qian; Rizzo, Maxime J.; Lupu, Roxana; Zimmerman, Neil T.; Saxena, Prabal; McElwain, Michael W.

    2017-01-01

    One of the key science goals of the Coronograph Instrument (CGI) on the WFIRST mission is to spectrally characterize the atmospheres of planets around other stars at extremely high contrast levels. To achieve this goal, the CGI Instrument will include a integral field spectrograph (IFS) as one of the two science cameras. We present the current science requirements that pertain to the IFS design, describe how our design implementation flows from these requirements, and outline our current instrument design.

  19. Emergency Medical Dispatch. National Standard Curriculum. Instructor Guide. Trainee Guide.

    ERIC Educational Resources Information Center

    National Highway Traffic Safety Administration (DOT), Washington, DC.

    This guide contains all instructor materials and requirements for the National Highway Traffic Safety Administration (NHTSA), Emergency Medical Dispatch (EMD) National Standard Curriculum. It includes lesson plans, instructional aids, and tools and supporting information designed to elevate trained and experienced public safety telecommunicators…

  20. Machine Trades Lab Management Guide.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Instructional Materials Lab.

    This manual was developed to guide machine trades instructors and vocational supervisors in sequencing laboratory instruction and controlling the flow of work for a 2-year machine trades training program. The first part of the guide provides information on program management (program description, safety concerns, academic issues, implementation…

  1. Veterinary Accreditation. A Reference Guide for Practitioners.

    ERIC Educational Resources Information Center

    Animal and Plant Health Inspection Service (USDA), Washington, DC.

    This reference manual was designed as a guide for veterinarians who have been accredited by the U.S. Department of Agriculture (USDA) Animal and Plant Health Inspection Services. The guide provides instructions on the following topics: identifying animals, reportable diseases and conditions, brucellosis, tuberculosis, pseudorabies, miscellaneous…

  2. Transportation systems safety hazard analysis tool (SafetyHAT) user guide (version 1.0)

    DOT National Transportation Integrated Search

    2014-03-24

    This is a user guide for the transportation system Safety Hazard Analysis Tool (SafetyHAT) Version 1.0. SafetyHAT is a software tool that facilitates System Theoretic Process Analysis (STPA.) This user guide provides instructions on how to download, ...

  3. Comprehensive Career Education Curriculum Guide for the Trainable.

    ERIC Educational Resources Information Center

    Mulligan, Robert E.; And Others

    Designed for use by teachers of the trainable mentally retarded, primary through postsecondary levels, this curriculum guide integrates development of verbal and written communication skills with the student's career development. The guide contains instructional objectives, suggested learning activities and teaching techniques, and information on…

  4. Idaho Driver Education Administrative Guide.

    ERIC Educational Resources Information Center

    Idaho State Dept. of Education, Boise.

    This guide provides information for school administrators and directors of commercial driver training schools about conducting driver education courses in Idaho. The first part of the guide, which applies to both public schools and commercial schools, covers the following areas: administration, sample letters and forms, instructional time…

  5. Russian Basic Course: Dialogue Cartoon Guides, Lessons 1-83.

    ERIC Educational Resources Information Center

    Defense Language Inst., Washington, DC.

    This booklet of cartoon guides contains 83 units of instructional materials prepared by the Defense Language Insitute for use in an intensive, conversational, Russian course. Included are cartoon guides to dialogues and dialogue recombinations which focus on social concerns and military matters. (RL)

  6. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Guida, K; Qamar, K; Thompson, M

    Purpose: The RTOG 1005 trial offered a hypofractionated arm in delivering WBRT+SIB. Traditionally, treatments were planned at our institution using field-in-field (FiF) tangents with a concurrent 3D conformal boost. With the availability of VMAT, it is possible that a hybrid VMAT-3D planning technique could provide another avenue in treating WBRT+SIB. Methods: A retrospective study of nine patients previously treated using RTOG 1005 guidelines was performed to compare FiF+3D plans with the hybrid technique. A combination of static tangents and partial VMAT arcs were used in base-dose optimization. The hybrid plans were optimized to deliver 4005cGy to the breast PTVeval andmore » 4800cGy to the lumpectomy PTVeval over 15 fractions. Plans were optimized to meet the planning goals dictated by RTOG 1005. Results: Hybrid plans yielded similar coverage of breast and lumpectomy PTVs (average D95 of 4013cGy compared to 3990cGy for conventional), while reducing the volume of high dose within the breast; the average D30 and D50 for the hybrid technique were 4517cGy and 4288cGy, compared to 4704cGy and 4377cGy for conventional planning. Hybrid plans increased conformity as well, yielding CI95% values of 1.22 and 1.54 for breast and lumpectomy PTVeval volumes; in contrast, conventional plans averaged 1.49 and 2.27, respectively. The nearby organs at risk (OARs) received more low dose with the hybrid plans due to low dose spray from the partial arcs, but all hybrid plans did meet the acceptable constraints, at a minimum, from the protocol. Treatment planning time was also reduced, as plans were inversely optimized (VMAT) rather than forward optimized. Conclusion: Hybrid-VMAT could be a solution in delivering WB+SIB, as plans yield very conformal treatment plans and maintain clinical standards in OAR sparing. For treating breast cancer patients with a simultaneously-integrated boost, Hybrid-VMAT offers superiority in dosimetric conformity and planning time as compared to FIF techniques.« less

  7. Business Ownership and Management. Arkansas Public School Course Content Guide.

    ERIC Educational Resources Information Center

    Arkansas State Dept. of Education, Little Rock.

    This course content guide was developed in accordance with the Standards for Accreditation of Public Schools adopted by the Arkansas State Board of Education. The guide is offered as a framework upon which a curriculum can be built. Within the subject area and at each grade level, the content guide identifies skills at three instructional levels:…

  8. Exploratory Coordinated Career Education. Arkansas Public School Course Content Guide.

    ERIC Educational Resources Information Center

    Arkansas State Dept. of Education, Little Rock.

    This course content guide was developed in accordance with the Standards for Accreditation of Public Schools adopted by the Arkansas State Board of Education. The guide is offered as a framework upon which a curriculum can be built. Within the subject area and at each grade level, the content guide identifies skills at three instructional levels:…

  9. Junior High Business Education. Arkansas Public School Course Content Guide.

    ERIC Educational Resources Information Center

    Arkansas State Dept. of Education, Little Rock.

    This course content guide was developed in accordance with the Standards for Accreditation of Public Schools adopted by the Arkansas State Board of Education. The guide is offered as a framework upon which a curriculum can be built. Within the subject area and at each grade level, the content guide identifies skills at three instructional levels:…

  10. Guide d'enseignement: Art dramatique, Secondaire, Deuxieme cycle (Instructional Guide: Theater Arts, Secondary Schools, Second Cycle).

    ERIC Educational Resources Information Center

    Alberta Dept. of Education, Edmonton. Language Services Branch.

    Intended to aid teachers in charge of implementing drama programs, this guide (in French) is to be employed in conjunction with the "1992 Second Cycle Secondary Drama Program of Studies" (Alberta, Canada). The guide's sections are as follows: (1) Introduction; (2) L'Adolescent; (3) Securite (discussing both emotional and physical…

  11. A Resource Guide for Teachers of Hindu Literature.

    ERIC Educational Resources Information Center

    Meehan, John L., Ed.; And Others

    Focusing on Hinduism, India, and Indian literature, this course guide offers help in organizing a course or units of instruction. The guide contains a historical outline of the evolution of Hinduism over a period of 3,000 years; a glossary listing terms in the guide and in Hindu literature; five courses of different time lengths (the literature of…

  12. See Also:physica status solidi (b)physica status solidi (c)Copyright © 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

  13. Get Sample Copy
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  1. The effect of guided inquiry-based instruction in secondary science for students with learning disabilities

    NASA Astrophysics Data System (ADS)

    Eliot, Michael H.

    Students with learning disabilities (SWLDs) need to attain academic rigor to graduate from high school and college, as well as achieve success in life. Constructivist theories suggest that guided inquiry may provide the impetus for their success, yet little research has been done to support this premise. This study was designed to fill that gap. This quasi-experimental study compared didactic and guided inquiry-based teaching of science concepts to secondary SWLDs in SDC science classes. The study examined 38 students in four classes at two diverse, urban high schools. Participants were taught two science concepts using both teaching methods and posttested after each using paper-and-pencil tests and performance tasks. Data were compared to determine increases in conceptual understanding by teaching method, order of teaching method, and exposure one or both teaching methods. A survey examined participants' perceived self-efficacy under each method. Also, qualitative comparison of the two test formats examined appropriate use with SWLDs. Results showed significantly higher scores after the guided inquiry method on concept of volume, suggesting that guided inquiry does improve conceptual understanding over didactic instruction in some cases. Didactic teaching followed by guided inquiry resulted in higher scores than the reverse order, indicating that SWLDs may require direct instruction in basic facts and procedures related to a topic prior to engaging in guided inquiry. Also application of both teaching methods resulted in significantly higher scores than a single method on the concept of density, suggesting that SWLDs may require more in depth instruction found using both methods. No differences in perceived self-efficacy were shown. Qualitative analysis both assessments and participants' behaviors during testing support the use of performance tasks over paper-and-pencil tests with SWLDs. Implications for education include the use of guided inquiry to increase SWLDs conceptual understanding and process skills, while improving motivation and participation through hands-on learning. In addition, teachers may use performance tasks to better assess students' thought process, problem solving skills, and conceptual understanding. However, constructivist teaching methods require extra training, pedagogical skills, subject matter knowledge, physical resources, and support from all stakeholders.

  2. Food Science & Technology. Instructor Guide. Student Reference.

    ERIC Educational Resources Information Center

    Martin, Phillip

    This packet contains an instructor curriculum guide and a student reference book for a course in food science and technology. The 4-unit curriculum contains 23 lessons. The instructor's guide contains the following components of a unit of instruction: objectives, competencies, motivational techniques, teaching procedures, other activities,…

  3. A Guide to Laboratory Practicum on Mechanics

    NASA Astrophysics Data System (ADS)

    Rusu, A. S.; Rusu, S. S.; Pirtac, C.

    2012-12-01

    The Guide represent a Laboratory practicum in mechanics for students from the Technical University of Moldova. The works are modernized as compared with older ones put in 1964 by Computer assistance. Each work contains theoretical framework, a work instruction and control questions. The Guide contains 27 figures.

  4. Improvement Guides for I.A. Curriculum

    ERIC Educational Resources Information Center

    Ritz, John M.; Wright, Lawrence S.

    1977-01-01

    Describes a project to revise "The Wisconsin Guide to Local Curriculum Improvement in Industrial Education, K-12", originally prepared in 1973. Four figures from the guide are included: (1) model of a field objective, (2) curriculum planning model, (3) instructional development process, and (4) process for developing objectives. (MF)

  5. Context-Model-Based Instruction in Teaching EFL Writing: A Narrative Inquiry

    ERIC Educational Resources Information Center

    Lin, Zheng

    2016-01-01

    This study aims to re-story the provision of the context-model-based instruction in teaching EFL writing, focusing especially on students' development of the context model and learning to guide EFL writing with the context model. The research data have been collected from the audio recordings of the classroom instruction, the teacher-researcher's…

  6. Strategy Instruction for Students with Learning Disabilities. What Works for Special Needs Learners

    ERIC Educational Resources Information Center

    Reid, Robert; Lienemann, Torri Ortiz

    2006-01-01

    Practical and accessible, this book provides the first step-by-step guide to cognitive strategy instruction, which has been shown to be one of the most effective instructional techniques for students with learning problems. Presented are proven strategies that students can use to improve their self-regulated learning, study skills, and performance…

  7. Designing Open and Individualized Instruction at the Elementary Level: A Guide for the Individual Teacher.

    ERIC Educational Resources Information Center

    Feldhusen, John; And Others

    A description of open and individualized elementary school instruction is provided. The goals of such instruction are to: 1) teach basic skills in language arts, math, science, and social studies; 2) develop higher cognitive abilities, such as problem solving; and 3) develop the child's social competence and self-concept. Open, individualized…

  8. Compressed Natural Gas Installation. A Video-Based Training Program for Vehicle Conversion. Instructor's Edition.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

    This instructor's guide contains the materials required to teach four competency-based course units of instruction in installing compressed natural gas (CNG) systems in motor vehicles. It is designed to accompany an instructional videotape (not included) on CNG installation. The following competencies are covered in the four instructional units:…

  9. The CGE-PLATO Electronic Laboratory Instructional Programs. (August 1, 1972 Through June 30, 1975).

    ERIC Educational Resources Information Center

    Neal, J. P.

    Twelve PLATO lessons are reproduced in this document to show the status of computer guided experimentation (CGE) instructional programs. The lesson topics include a description of the CGE-PLATO instructional laboratory, an introduction to CGE-PLATO tests and special software routines, router lesson for two electrical engineering courses, and an…

  10. "Learning Maps" vs. "Instructional Maps": User Guide for Learners vs. Instructional Tool for Designers

    ERIC Educational Resources Information Center

    Gropper, George L.

    2016-01-01

    A prescription favored in this article calls for the joint use of "learning maps" and "instructional maps." Why then the "Vs." in the title? Simply put, it is a rhetorical device. It calls attention to a key difference between the two. This article explicates the difference. It also informs how alone and in…

  11. Using Curriculum-Based Assessment and Curriculum-Based Measurement to Guide Elementary Mathematics Instruction: Effect on Individual and Group Accountability Scores

    ERIC Educational Resources Information Center

    VanDerHeyden, Amanda M.; Burns, Matthew K.

    2005-01-01

    No Child Left Behind mandates accountability data for school districts. This mandate has led to increased attention to instruction and academic remediation among educational researchers. The current study used schoolwide curriculum-based assessment (CBA) and curriculum-based measurement (CBM) data to plan and deliver mathematics instruction to…

  12. Impact of Guided-Inquiry-Based Instruction with a Writing and Reflection Emphasis on Chemistry Students' Critical Thinking Abilities

    ERIC Educational Resources Information Center

    Gupta, Tanya; Burke, K. A.; Mehta, Akash; Greenbowe, Thomas J.

    2015-01-01

    The Science Writing Heuristic (SWH) laboratory instruction approach has been used successfully over a decade to engage students in laboratory activities. SWH-based instruction emphasizes knowledge construction through individual writing and reflection, and collaborative learning as a group. In the SWH approach, writing is a core component of…

  13. Webquest 2.0: An Instructional Model for Digital Learners

    ERIC Educational Resources Information Center

    Dell, Diana F. Abernathy

    2012-01-01

    Teaching and learning tools such as Moodle and Web 2.0 tools are appearing in K-12 classrooms; however, there is a lack of scholarly research to guide the implementation of these tools. The WebQuest model, a widely adopted inquiry-based model for online instruction, has instructional inadequacies and does not make the most of emerging…

  14. A Guide to the Use of Non-Projected Displays. Teaching and Learning in Higher Education, 13.

    ERIC Educational Resources Information Center

    Ellington, Henry

    A sequel to the booklet "A Review of the Different Types of Instructional Materials Available to Teachers and Lecturers," this booklet begins by looking at the potential role of non-projected displays in different instruction situations, i.e., mass instruction, individualized learning, and group learning. Four main classes of non-projected…

  15. The Impact of Instructional Supervision on Academic Performance of Secondary School Students in Nasarawa State, Nigeria

    ERIC Educational Resources Information Center

    Usman, Yunusa Dangara

    2015-01-01

    This study examined the Impact of Instructional Supervision on Academic Performance of Secondary School Students in Nasarawa State with reference to Senior Secondary Certificate Examination (SSCE). Five research questions were used to guide the study to a rational conclusion. Descriptive Survey method was adopted in which Instructional Supervision…

  16. Industrial Arts Power Mechanics. Applying Scientific Principles to Power, Energy, Force. Instructional Units.

    ERIC Educational Resources Information Center

    Woodward, Robert L.; Myers, Norman L.

    The instructional units and related materials in this guide are designed to assist in the preparation of courses of study/instruction in (1) power mechanics specifically, (2) power mechanics which serve as introductory courses in other areas of industrial arts, and (3) automotive mechanics which also cover the broader aspects of power mechanics.…

  17. School Climate Improvement Action Guide for Instructional Staff. School Climate Improvement Resource Package

    ERIC Educational Resources Information Center

    National Center on Safe Supportive Learning Environments, 2017

    2017-01-01

    Improving school climate takes time and commitment from a variety of people in a variety of roles. This document outlines key action steps that instructional staff--including teachers, paraprofessionals, and others in the classroom who provide instruction or assistance--can take to support school climate improvements. Key action steps are provided…

  18. Quality Mathematics Instructional Practices Contributing to Student Achievements in Five High-Achieving Asian Education Systems: An Analysis Using TIMSS 2011 Data

    ERIC Educational Resources Information Center

    Cheng, Qiang

    2014-01-01

    Although teaching quality is seen as crucial in affecting students' performance, what types of instructional practices constitute quality teaching remains a question. With the theoretical assumptions of conceptual and procedural mathematics teaching as a guide, this study examined the types of quality mathematics instructional practices that…

  19. See Also:Mechanics of Cohesive-frictional MaterialsCopyright © 2004 John Wiley & Sons, Ltd.Get Sample Copy

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