The keys to CERN conference rooms - Managing local collaboration facilities in large organisations

NASA Astrophysics Data System (ADS)

Baron, T.; Domaracky, M.; Duran, G.; Fernandes, J.; Ferreira, P.; Gonzalez Lopez, J. B.; Jouberjean, F.; Lavrut, L.; Tarocco, N.

2014-06-01

For a long time HEP has been ahead of the curve in its usage of remote collaboration tools, like videoconference and webcast, while the local CERN collaboration facilities were somewhat behind the expected quality standards for various reasons. This time is now over with the creation by the CERN IT department in 2012 of an integrated conference room service which provides guidance and installation services for new rooms (either equipped for videoconference or not), as well as maintenance and local support. Managing now nearly half of the 246 meeting rooms available on the CERN sites, this service has been built to cope with the management of all CERN rooms with limited human resources. This has been made possible by the intensive use of professional software to manage and monitor all the room equipment, maintenance and activity. This paper focuses on presenting these packages, either off-the-shelf commercial products (asset and maintenance management tool, remote audio-visual equipment monitoring systems, local automation devices, new generation touch screen interfaces for interacting with the room) when available or locally developed integration and operational layers (generic audio-visual control and monitoring framework) and how they help overcoming the challenges presented by such a service. The aim is to minimise local human interventions while preserving the highest service quality and placing the end user back in the centre of this collaboration platform.

Halting Antipsychotic Use in Long-Term care (HALT): a single-arm longitudinal study aiming to reduce inappropriate antipsychotic use in long-term care residents with behavioral and psychological symptoms of dementia.

PubMed

Jessop, Tiffany; Harrison, Fleur; Cations, Monica; Draper, Brian; Chenoweth, Lynn; Hilmer, Sarah; Westbury, Juanita; Low, Lee-Fay; Heffernan, Megan; Sachdev, Perminder; Close, Jacqueline; Blennerhassett, Jenny; Marinkovich, Millicent; Shell, Allan; Brodaty, Henry

2017-08-01

Inappropriate use of antipsychotic medications to manage Behavioral and Psychological Symptoms of Dementia (BPSD) continues despite revised guidelines and evidence for the associated risks and side effects. The aim of the Halting Antipsychotic Use in Long-Term care (HALT) project is to identify residents of long-term care (LTC) facilities on antipsychotic medications, and undertake an intervention to deprescribe (or cease) these medicines and improve non-pharmacological behavior management. LTC facilities will be recruited across Sydney, Australia. Resident inclusion criteria will be aged over 60 years, on regular antipsychotic medication, and without a primary psychotic illness or very severe BPSD, as measured using the Neuropsychiatric Inventory (NPI). Data collection will take place one month and one week prior to commencement of deprescribing; and 3, 6 and 12 months later. During the period prior to deprescribing, training will be provided for care staff on how to reduce and manage BPSD using person-centered approaches, and general practitioners of participants will be provided academic detailing. The primary outcome measure will be reduction of regular antipsychotic medication without use of substitute psychotropic medications. Secondary outcome measures will be NPI total and domain scores, Cohen-Mansfield Agitation Inventory scores and adverse events, including falls and hospitalizations. While previous studies have described strategies to minimize inappropriate use of antipsychotic medications in people with dementia living in long-term care, sustainability and a culture of prescribing for BPSD in aged care remain challenges. The HALT project aims to evaluate the feasibility of a multi-disciplinary approach for deprescribing antipsychotics in this population.

Geant4 simulation of the CERN-EU high-energy reference field (CERF) facility.

PubMed

Prokopovich, D A; Reinhard, M I; Cornelius, I M; Rosenfeld, A B

2010-09-01

The CERN-EU high-energy reference field facility is used for testing and calibrating both active and passive radiation dosemeters for radiation protection applications in space and aviation. Through a combination of a primary particle beam, target and a suitable designed shielding configuration, the facility is able to reproduce the neutron component of the high altitude radiation field relevant to the jet aviation industry. Simulations of the facility using the GEANT4 (GEometry ANd Tracking) toolkit provide an improved understanding of the neutron particle fluence as well as the particle fluence of other radiation components present. The secondary particle fluence as a function of the primary particle fluence incident on the target and the associated dose equivalent rates were determined at the 20 designated irradiation positions available at the facility. Comparisons of the simulated results with previously published simulations obtained using the FLUKA Monte Carlo code, as well as with experimental results of the neutron fluence obtained with a Bonner sphere spectrometer, are made.

Light ion production for a future radiobiological facility at CERN: preliminary studies.

PubMed

Stafford-Haworth, Joshua; Bellodi, Giulia; Küchler, Detlef; Lombardi, Alessandra; Röhrich, Jörg; Scrivens, Richard

2014-02-01

Recent medical applications of ions such as carbon and helium have proved extremely effective for the treatment of human patients. However, before now a comprehensive study of the effects of different light ions on organic targets has not been completed. There is a strong desire for a dedicated facility which can produce ions in the range of protons to neon in order to perform this study. This paper will present the proposal and preliminary investigations into the production of light ions, and the development of a radiobiological research facility at CERN. The aims of this project will be presented along with the modifications required to the existing linear accelerator (Linac3), and the foreseen facility, including the requirements for an ion source in terms of some of the specification parameters and the flexibility of operation for different ion types. Preliminary results from beam transport simulations will be presented, in addition to some planned tests required to produce some of the required light ions (lithium, boron) to be conducted in collaboration with the Helmholtz-Zentrum für Materialien und Energie, Berlin.

CERN@school: bringing CERN into the classroom

NASA Astrophysics Data System (ADS)

Whyntie, T.; Cook, J.; Coupe, A.; Fickling, R. L.; Parker, B.; Shearer, N.

2016-04-01

CERN@school brings technology from CERN into the classroom to aid with the teaching of particle physics. It also aims to inspire the next generation of physicists and engineers by giving participants the opportunity to be part of a national collaboration of students, teachers and academics, analysing data obtained from detectors based on the ground and in space to make new, curiosity-driven discoveries at school. CERN@school is based around the Timepix hybrid silicon pixel detector developed by the Medipix 2 Collaboration, which features a 300 μm thick silicon sensor bump-bonded to a Timepix readout ASIC. This defines a 256-by-256 grid of pixels with a pitch of 55 μm, the data from which can be used to visualise ionising radiation in a very accessible way. Broadly speaking, CERN@school consists of a web portal that allows access to data collected by the Langton Ultimate Cosmic ray Intensity Detector (LUCID) experiment in space and the student-operated Timepix detectors on the ground; a number of Timepix detector kits for ground-based experiments, to be made available to schools for both teaching and research purposes; and educational resources for teachers to use with LUCID data and detector kits in the classroom. By providing access to cutting-edge research equipment, raw data from ground and space-based experiments, CERN@school hopes to provide the foundation for a programme that meets the many of the aims and objectives of CERN and the project's supporting academic and industrial partners. The work presented here provides an update on the status of the programme as supported by the UK Science and Technology Facilities Council (STFC) and the Royal Commission for the Exhibition of 1851. This includes recent results from work with the GridPP Collaboration on using grid resources with schools to run GEANT4 simulations of CERN@school experiments.

[Healthcare-associated infections and antimicrobial use in long term care facilities (HALT-2): German results of the second European prevalence survey].

PubMed

Ruscher, Claudia; Kraus-Haas, Martina; Nassauer, Alfred; Mielke, Martin

2015-04-01

Prevention of infections and strategies for the prudent use of antimicrobials in long-term care facilities have gained importance in view of the demographic changes, not only in Germany. To generate appropriate data and to identify relevant aspects of infection prevention in this field, the European Centre for Disease Prevention and Control (ECDC) launched the second point prevalence survey of healthcare-associated infections and antimicrobial use in European long-term care facilities in 2013 (HALT-2). Despite methodical adjustments in the collection of data on healthcare-associated infections, in this second survey healthcare workers in the participating facilities were intensively trained in methodology and data collection. Overall, 221 German facilities participated and collected data from 17,208 residents. Well-established structures of regional networks facilitated the recruitment of participants as well as the preparations for training and survey. The median prevalence of residents receiving at least one antimicrobial agent was 1.1% (95 %-CI 0,7-1,6)), which is remarkably low. However, the most frequently used antimicrobials in German facilities beside beta-lactams (penicillins 18.2%, other beta-lactams 17.2%) were quinolones (28.2%). Data collection of infections was performed based on signs and symptoms in detailed decision algorithms according to the recently updated McGeer surveillance criteria and yielded a median prevalence of 1.7% (95 %-CI 1,1-2,2). Symptomatic urinary tract infections (28.4%), skin and soft tissue infection (27.9%), and respiratory tract infections (24.7%) were identified both as the most common types of infections and the most common indications for the use of systemic antimicrobials. Clinical implications evolve mainly from the high use of quinolones. In terms of infection prevention measures, compliance of health care workers with a hand hygiene regimen revealed further potential for improvement.

Light ion production for a future radiobiological facility at CERN: Preliminary studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stafford-Haworth, Joshua, E-mail: Joshua.Stafford-Haworth@cern.ch; John Adams Institute at Royal Holloway, University of London, Egham, Surrey TW20 0EX; Bellodi, Giulia

2014-02-15

Recent medical applications of ions such as carbon and helium have proved extremely effective for the treatment of human patients. However, before now a comprehensive study of the effects of different light ions on organic targets has not been completed. There is a strong desire for a dedicated facility which can produce ions in the range of protons to neon in order to perform this study. This paper will present the proposal and preliminary investigations into the production of light ions, and the development of a radiobiological research facility at CERN. The aims of this project will be presented alongmore » with the modifications required to the existing linear accelerator (Linac3), and the foreseen facility, including the requirements for an ion source in terms of some of the specification parameters and the flexibility of operation for different ion types. Preliminary results from beam transport simulations will be presented, in addition to some planned tests required to produce some of the required light ions (lithium, boron) to be conducted in collaboration with the Helmholtz-Zentrum für Materialien und Energie, Berlin.« less

HALT Selected Papers, 1993 with Language Teaching Ideas from Paradise.

ERIC Educational Resources Information Center

Chandler, Paul, Ed.; Hodnett, Edda, Ed.

In section I, papers presented at the Hawaii Association of Language Teachers (HALT) in 1993 are presented. Section II includes a number of projects received from a call for papers simultaneous to the call for the HALT papers. Section 1 contains: "This is Like a Foreign Language to Me: Keynote Address" (Bill VanPatten); "From Discussion Questions…

Performance of a liquid argon time projection chamber exposed to the CERN West Area Neutrino Facility neutrino beam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arneodo, F.; Cavanna, F.; Mitri, I. De

2006-12-01

We present the results of the first exposure of a Liquid Argon TPC to a multi-GeV neutrino beam. The data have been collected with a 50 liters ICARUS-like chamber located between the CHORUS and NOMAD experiments at the CERN West Area Neutrino Facility (WANF). We discuss both the instrumental performance of the detector and its capability to identify and reconstruct low-multiplicity neutrino interactions.

The n_TOF facility: Neutron beams for challenging future measurements at CERN

NASA Astrophysics Data System (ADS)

Chiaveri, E.; Aberle, O.; Andrzejewski, J.; Audouin, L.; Bacak, M.; Balibrea, J.; Barbagallo, M.; Bečvář, F.; Berthoumieux, E.; Billowes, J.; Bosnar, D.; Brown, A.; Caamaño, M.; Calviño, F.; Calviani, M.; Cano-Ott, D.; Cardella, R.; Casanovas, A.; Cerutti, F.; Chen, Y. H.; Colonna, N.; Cortés, G.; Cortés-Giraldo, M. A.; Cosentino, L.; Damone, L. A.; Diakaki, M.; Domingo-Pardo, C.; Dressler, R.; Dupont, E.; Durán, I.; Fernández-Domínguez, B.; Ferrari, A.; Ferreira, P.; Finocchiaro, P.; Göbel, K.; García, A. R.; Gawlik, A.; Gilardoni, S.; Glodariu, T.; Gonçalves, I. F.; González, E.; Griesmayer, E.; Guerrero, C.; Gunsing, F.; Harada, H.; Heinitz, S.; Heyse, J.; Jenkins, D. G.; Jericha, E.; Käppeler, F.; Kadi, Y.; Kalamara, A.; Kavrigin, P.; Kimura, A.; Kivel, N.; Kokkoris, M.; Krtička, M.; Kurtulgil, D.; Leal-Cidoncha, E.; Lederer, C.; Leeb, H.; Lerendegui-Marco, J.; Meo, S. Lo; Lonsdale, S. J.; Macina, D.; Marganiec, J.; Martínez, T.; Masi, A.; Massimi, C.; Mastinu, P.; Mastromarco, M.; Maugeri, E. A.; Mazzone, A.; Mendoza, E.; Mengoni, A.; Milazzo, P. M.; Mingrone, F.; Musumarra, A.; Negret, A.; Nolte, R.; Oprea, A.; Patronis, N.; Pavlik, A.; Perkowski, J.; Porras, I.; Praena, J.; Quesada, J. M.; Radeck, D.; Rauscher, T.; Reifarth, R.; Rubbia, C.; Ryan, J. A.; Sabaté-Gilarte, M.; Saxena, A.; Schillebeeckx, P.; Schumann, D.; Smith, A. G.; Sosnin, N. V.; Stamatopoulos, A.; Tagliente, G.; Tain, J. L.; Tarifeño-Saldivia, A.; Tassan-Got, L.; Tsinganis, A.; Valenta, S.; Vannini, G.; Variale, V.; Vaz, P.; Ventura, A.; Vlachoudis, V.; Vlastou, R.; Wallner, A.; Warren, S.; Woods, P. J.; Wright, T.; Žugec, P.

2017-09-01

The CERN n_TOF neutron beam facility is characterized by a very high instantaneous neutron flux, excellent TOF resolution at the 185 m long flight path (EAR-1), low intrinsic background and coverage of a wide range of neutron energies, from thermal to a few GeV. These characteristics provide a unique possibility to perform high-accuracy measurements of neutron-induced reaction cross-sections and angular distributions of interest for fundamental and applied Nuclear Physics. Since 2001, the n_TOF Collaboration has collected a wealth of high quality nuclear data relevant for nuclear astrophysics, nuclear reactor technology, nuclear medicine, etc. The overall efficiency of the experimental program and the range of possible measurements has been expanded with the construction of a second experimental area (EAR-2), located 20 m on the vertical of the n_TOF spallation target. This upgrade, which benefits from a neutron flux 30 times higher than in EAR-1, provides a substantial extension in measurement capabilities, opening the possibility to collect data on neutron cross-section of isotopes with short half-lives or available in very small amounts. This contribution will outline the main characteristics of the n_TOF facility, with special emphasis on the new experimental area. In particular, we will discuss the innovative features of the EAR-2 neutron beam that make possible to perform very challenging measurements on short-lived radioisotopes or sub-mg samples, out of reach up to now at other neutron facilities around the world. Finally, the future perspectives of the facility will be presented.

High-alkali low-temperature polysulfide pulping (HALT) of Scots pine.

PubMed

Paananen, Markus; Sixta, Herbert

2015-10-01

High-alkali low-temperature polysulfide pulping (HALT) was effectively utilised to prevent major polysaccharide losses while maintaining the delignification rate. A yield increase of 6.7 wt% on wood was observed for a HALT pulp compared to a conventionally produced kappa number 60 pulp with comparable viscosity. Approximately 70% of the yield increase was attributed to improved galactoglucomannan preservation and 30% to cellulose. A two-stage oxygen delignification sequence with inter-stage peroxymonosulphuric acid treatment was used to ensure delignification to a bleachable grade. In a comparison to conventional pulp, HALT pulp effectively maintained its yield advantage. Diafiltration trials indicate that purified black liquor can be directly recycled, as large lignin fractions and basically all dissolved polysaccharides were separated from the alkali-rich BL. Copyright © 2015 Elsevier Ltd. All rights reserved.

Status and Planned Experiments of the Hiradmat Pulsed Beam Material Test Facility at CERN SPS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Charitonidis, Nikolaos; Efthymiopoulos, Ilias; Fabich, Adrian

2015-06-01

HiRadMat (High Irradiation to Materials) is a facility at CERN designed to provide high-intensity pulsed beams to an irradiation area where material samples as well as accelerator component assemblies (e.g. vacuum windows, shock tests on high power targets, collimators) can be tested. The beam parameters (SPS 440 GeV protons with a pulse energy of up to 3.4 MJ, or alternatively lead/argon ions at the proton equivalent energy) can be tuned to match the needs of each experiment. It is a test area designed to perform single pulse experiments to evaluate the effect of high-intensity pulsed beams on materials in amore » dedicated environment, excluding long-time irradiation studies. The facility is designed for a maximum number of 1016 protons per year, in order to limit the activation of the irradiated samples to acceptable levels for human intervention. This paper will demonstrate the possibilities for research using this facility and go through examples of upcoming experiments scheduled in the beam period 2015/2016.« less

HALT to qualify electronic packages: a proof of concept

NASA Astrophysics Data System (ADS)

Ramesham, Rajeshuni

2014-03-01

A proof of concept of the Highly Accelerated Life Testing (HALT) technique was explored to assess and optimize electronic packaging designs for long duration deep space missions in a wide temperature range (-150°C to +125°C). HALT is a custom hybrid package suite of testing techniques using environments such as extreme temperatures and dynamic shock step processing from 0g up to 50g of acceleration. HALT testing used in this study implemented repetitive shock on the test vehicle components at various temperatures to precipitate workmanship and/or manufacturing defects to show the weak links of the designs. The purpose is to reduce the product development cycle time for improvements to the packaging design qualification. A test article was built using advanced electronic package designs and surface mount technology processes, which are considered useful for a variety of JPL and NASA projects, i.e. (surface mount packages such as ball grid arrays (BGA), plastic ball grid arrays (PBGA), very thin chip array ball grid array (CVBGA), quad flat-pack (QFP), micro-lead-frame (MLF) packages, several passive components, etc.). These packages were daisy-chained and independently monitored during the HALT test. The HALT technique was then implemented to predict reliability and assess survivability of these advanced packaging techniques for long duration deep space missions in much shorter test durations. Test articles were built using advanced electronic package designs that are considered useful in various NASA projects. All the advanced electronic packages were daisychained independently to monitor the continuity of the individual electronic packages. Continuity of the daisy chain packages was monitored during the HALT testing using a data logging system. We were able to test the boards up to 40g to 50g shock levels at temperatures ranging from +125°C to -150°C. The HALT system can deliver 50g shock levels at room temperature. Several tests were performed by subjecting

Quantum Iterative Deepening with an Application to the Halting Problem

PubMed Central

Tarrataca, Luís; Wichert, Andreas

2013-01-01

Classical models of computation traditionally resort to halting schemes in order to enquire about the state of a computation. In such schemes, a computational process is responsible for signaling an end of a calculation by setting a halt bit, which needs to be systematically checked by an observer. The capacity of quantum computational models to operate on a superposition of states requires an alternative approach. From a quantum perspective, any measurement of an equivalent halt qubit would have the potential to inherently interfere with the computation by provoking a random collapse amongst the states. This issue is exacerbated by undecidable problems such as the Entscheidungsproblem which require universal computational models, e.g. the classical Turing machine, to be able to proceed indefinitely. In this work we present an alternative view of quantum computation based on production system theory in conjunction with Grover's amplitude amplification scheme that allows for (1) a detection of halt states without interfering with the final result of a computation; (2) the possibility of non-terminating computation and (3) an inherent speedup to occur during computations susceptible of parallelization. We discuss how such a strategy can be employed in order to simulate classical Turing machines. PMID:23520465

First experimental evidence of hydrodynamic tunneling of ultra–relativistic protons in extended solid copper target at the CERN HiRadMat facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schmidt, R.; Grenier, D.; Wollmann, D.

2014-08-15

A novel experiment has been performed at the CERN HiRadMat test facility to study the impact of the 440 GeV proton beam generated by the Super Proton Synchrotron on extended solid copper cylindrical targets. Substantial hydrodynamic tunneling of the protons in the target material has been observed that leads to significant lengthening of the projectile range, which confirms our previous theoretical predictions [N. A. Tahir et al., Phys. Rev. Spec. Top.-Accel. Beams 15, 051003 (2012)]. Simulation results show very good agreement with the experimental measurements. These results have very important implications on the machine protection design for powerful machines like themore » Large Hadron Collider (LHC), the future High Luminosity LHC, and the proposed huge 80 km circumference Future Circular Collider, which is currently being discussed at CERN. Another very interesting outcome of this work is that one may also study the field of High Energy Density Physics at this test facility.« less

First experimental evidence of hydrodynamic tunneling of ultra-relativistic protons in extended solid copper target at the CERN HiRadMat facility

NASA Astrophysics Data System (ADS)

Schmidt, R.; Blanco Sancho, J.; Burkart, F.; Grenier, D.; Wollmann, D.; Tahir, N. A.; Shutov, A.; Piriz, A. R.

2014-08-01

A novel experiment has been performed at the CERN HiRadMat test facility to study the impact of the 440 GeV proton beam generated by the Super Proton Synchrotron on extended solid copper cylindrical targets. Substantial hydrodynamic tunneling of the protons in the target material has been observed that leads to significant lengthening of the projectile range, which confirms our previous theoretical predictions [N. A. Tahir et al., Phys. Rev. Spec. Top.-Accel. Beams 15, 051003 (2012)]. Simulation results show very good agreement with the experimental measurements. These results have very important implications on the machine protection design for powerful machines like the Large Hadron Collider (LHC), the future High Luminosity LHC, and the proposed huge 80 km circumference Future Circular Collider, which is currently being discussed at CERN. Another very interesting outcome of this work is that one may also study the field of High Energy Density Physics at this test facility.

Neutron capture cross section measurement of 151Sm at the CERN neutron time of flight facility (n_TOF).

PubMed

Abbondanno, U; Aerts, G; Alvarez-Velarde, F; Alvarez-Pol, H; Andriamonje, S; Andrzejewski, J; Badurek, G; Baumann, P; Becvár, F; Benlliure, J; Berthoumieux, E; Calviño, F; Cano-Ott, D; Capote, R; Cennini, P; Chepel, V; Chiaveri, E; Colonna, N; Cortes, G; Cortina, D; Couture, A; Cox, J; Dababneh, S; Dahlfors, M; David, S; Dolfini, R; Domingo-Pardo, C; Duran, I; Embid-Segura, M; Ferrant, L; Ferrari, A; Ferreira-Marques, R; Frais-Koelbl, H; Furman, W; Goncalves, I; Gallino, R; Gonzalez-Romero, E; Goverdovski, A; Gramegna, F; Griesmayer, E; Gunsing, F; Haas, B; Haight, R; Heil, M; Herrera-Martinez, A; Isaev, S; Jericha, E; Käppeler, F; Kadi, Y; Karadimos, D; Kerveno, M; Ketlerov, V; Koehler, P; Konovalov, V; Krticka, M; Lamboudis, C; Leeb, H; Lindote, A; Lopes, I; Lozano, M; Lukic, S; Marganiec, J; Marrone, S; Martinez-Val, J; Mastinu, P; Mengoni, A; Milazzo, P M; Molina-Coballes, A; Moreau, C; Mosconi, M; Neves, F; Oberhummer, H; O'Brien, S; Pancin, J; Papaevangelou, T; Paradela, C; Pavlik, A; Pavlopoulos, P; Perlado, J M; Perrot, L; Pignatari, M; Plag, R; Plompen, A; Plukis, A; Poch, A; Policarpo, A; Pretel, C; Quesada, J; Raman, S; Rapp, W; Rauscher, T; Reifarth, R; Rosetti, M; Rubbia, C; Rudolf, G; Rullhusen, P; Salgado, J; Soares, J C; Stephan, C; Tagliente, G; Tain, J; Tassan-Got, L; Tavora, L; Terlizzi, R; Vannini, G; Vaz, P; Ventura, A; Villamarin, D; Vincente, M C; Vlachoudis, V; Voss, F; Wendler, H; Wiescher, M; Wisshak, K

2004-10-15

The151Sm(n,gamma)152Sm cross section has been measured at the spallation neutron facility n_TOF at CERN in the energy range from 1 eV to 1 MeV. The new facility combines excellent resolution in neutron time-of-flight, low repetition rates, and an unsurpassed instantaneous luminosity, resulting in rather favorable signal/background ratios. The 151Sm cross section is of importance for characterizing neutron capture nucleosynthesis in asymptotic giant branch stars. At a thermal energy of kT=30 keV the Maxwellian averaged cross section of this unstable isotope (t(1/2)=93 yr) was determined to be 3100+/-160 mb, significantly larger than theoretical predictions.

The measurement programme at the neutron time-of-flight facility n_TOF at CERN

NASA Astrophysics Data System (ADS)

Gunsing, F.; Aberle, O.; Andrzejewski, J.; Audouin, L.; Bécares, V.; Bacak, M.; Balibrea-Correa, J.; Barbagallo, M.; Barros, S.; Bečvář, F.; Beinrucker, C.; Belloni, F.; Berthoumieux, E.; Billowes, J.; Bosnar, D.; Brown, A.; Brugger, M.; Caamaño, M.; Calviño, F.; Calviani, M.; Cano-Ott, D.; Cardella, R.; Casanovas, A.; Castelluccio, D. M.; Cerutti, F.; Chen, Y. H.; Chiaveri, E.; Colonna, N.; Cortés-Giraldo, M. A.; Cortés, G.; Cosentino, L.; Damone, L. A.; Deo, K.; Diakaki, M.; Domingo-Pardo, C.; Dressler, R.; Dupont, E.; Durán, I.; Fernández-Domínguez, B.; Ferrari, A.; Ferreira, P.; Finocchiaro, P.; Frost, R. J. W.; Furman, V.; Ganesan, S.; García, A. R.; Gawlik, A.; Gheorghe, I.; Gilardoni, S.; Glodariu, T.; Gonçalves, I. F.; González, E.; Goverdovski, A.; Griesmayer, E.; Guerrero, C.; Göbel, K.; Harada, H.; Heftrich, T.; Heinitz, S.; Hernández-Prieto, A.; Heyse, J.; Jenkins, D. G.; Jericha, E.; Käppeler, F.; Kadi, Y.; Kalamara, A.; Katabuchi, T.; Kavrigin, P.; Ketlerov, V.; Khryachkov, V.; Kimura, A.; Kivel, N.; Kokkoris, M.; Krtička, M.; Kurtulgil, D.; Leal-Cidoncha, E.; Lederer, C.; Leeb, H.; Lerendegui, J.; Licata, M.; Meo, S. Lo; Lonsdale, S. J.; Losito, R.; Macina, D.; Marganiec, J.; Martínez, T.; Masi, A.; Massimi, C.; Mastinu, P.; Mastromarco, M.; Matteucci, F.; Maugeri, E. A.; Mazzone, A.; Mendoza, E.; Mengoni, A.; Milazzo, P. M.; Mingrone, F.; Mirea, M.; Montesano, S.; Musumarra, A.; Nolte, R.; Negret, A.; Oprea, A.; Palomo-Pinto, F. R.; Paradela, C.; Patronis, N.; Pavlik, A.; Perkowski, J.; Porras, I.; Praena, J.; Quesada, J. M.; Radeck, D.; Rajeev, K.; Rauscher, T.; Reifarth, R.; Riego-Perez, A.; Robles, M.; Rout, P.; Rubbia, C.; Ryan, J. A.; Sabaté-Gilarte, M.; Saxena, A.; Schillebeeckx, P.; Schmidt, S.; Schumann, D.; Sedyshev, P.; Smith, A. G.; Sosnin, N. V.; Stamatopoulos, A.; Suryanarayana, S. V.; Tagliente, G.; Tain, J. L.; Tarifeño-Saldivia, A.; Tarrío, D.; Tassan-Got, L.; Tsinganis, A.; Valenta, S.; Vannini, G.; Variale, V.; Vaz, P.; Ventura, A.; Vlachoudis, V.; Vlastou, R.; Wallner, A.; Warren, S.; Weigand, M.; Weiss, C.; Wolf, C.; Woods, P. J.; Wright, T.; Žugec, P.

2017-09-01

Neutron-induced reaction cross sections are important for a wide variety of research fields ranging from the study of nuclear level densities, nucleosynthesis to applications of nuclear technology like design, and criticality and safety assessment of existing and future nuclear reactors, radiation dosimetry, medical applications, nuclear waste transmutation, accelerator-driven systems and fuel cycle investigations. Simulations and calculations of nuclear technology applications largely rely on evaluated nuclear data libraries. The evaluations in these libraries are based both on experimental data and theoretical models. CERN's neutron time-of-flight facility n_TOF has produced a considerable amount of experimental data since it has become fully operational with the start of its scientific measurement programme in 2001. While for a long period a single measurement station (EAR1) located at 185 m from the neutron production target was available, the construction of a second beam line at 20 m (EAR2) in 2014 has substantially increased the measurement capabilities of the facility. An outline of the experimental nuclear data activities at n_TOF will be presented.

HiRadMat at CERN SPS - A test facility with high intensity beam pulses to material samples

DOE Office of Scientific and Technical Information (OSTI.GOV)

Charitonidis, N.; Fabich, A.; Efthymiopoulos, I.

2015-07-01

HiRadMat (High Irradiation to Materials) is a facility at CERN designed to provide high-intensity pulsed beams to an irradiation area where material samples as well as accelerator component assemblies (e.g. vacuum windows, shock tests on high power targets, collimators) can be tested. The beam parameters (SPS 440 GeV protons with a pulse energy of up to 3.4 MJ, or alternatively lead/argon ions at the proton equivalent energy) can be tuned to match the needs of each experiment. It is a test area designed to perform single pulse experiments to evaluate the effect of high-intensity pulsed beams on materials in amore » dedicated environment, excluding long-time irradiation studies. The facility is designed for a 10{sup 16} maximum number of protons per year, in order to limit the activation to acceptable levels for human intervention. This paper will demonstrate the possibilities for research using this facility and showing examples of upcoming experiments scheduled in the beam period 2014/2015. (authors)« less

INTEGRATED OPERATIONAL DOSIMETRY SYSTEM AT CERN.

PubMed

Dumont, Gérald; Pedrosa, Fernando Baltasar Dos Santos; Carbonez, Pierre; Forkel-Wirth, Doris; Ninin, Pierre; Fuentes, Eloy Reguero; Roesler, Stefan; Vollaire, Joachim

2017-04-01

CERN, the European Organization for Nuclear Research, upgraded its operational dosimetry system in March 2013 to be prepared for the first Long Shutdown of CERN's facilities. The new system allows the immediate and automatic checking and recording of the dosimetry data before and after interventions in radiation areas. To facilitate the analysis of the data in context of CERN's approach to As Low As Reasonably Achievable (ALARA), this new system is interfaced to the Intervention Management Planning and Coordination Tool (IMPACT). IMPACT is a web-based application widely used in all CERN's accelerators and their associated technical infrastructures for the planning, the coordination and the approval of interventions (work permit principle). The coupling of the operational dosimetry database with the IMPACT repository allows a direct and almost immediate comparison of the actual dose with the estimations, in addition to enabling the configuration of alarm levels in the dosemeter in function of the intervention to be performed. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

CERN and 60 years of science for peace

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heuer, Rolf-Dieter, E-mail: Rolf.Heuer@cern.ch

2015-02-24

This paper presents CERN as it celebrates its 60{sup th} Anniversary since its founding. The presentation first discusses the mission of CERN and its role as an inter-governmental Organization. The paper also reviews aspects of the particle physics research programme, looking at both current and future accelerator-based facilities at the high-energy and intensity frontiers. Finally, the paper considers issues beyond fundamental research, such as capacity-building and the interface between Art and Science.

STARS DO NOT EAT THEIR YOUNG MIGRATING PLANETS: EMPIRICAL CONSTRAINTS ON PLANET MIGRATION HALTING MECHANISMS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Plavchan, Peter; Bilinski, Christopher

The discovery of ''hot Jupiters'' very close to their parent stars confirmed that Jovian planets migrate inward via several potential mechanisms. We present empirical constraints on planet migration halting mechanisms. We compute model density functions of close-in exoplanets in the orbital semi-major axis-stellar mass plane to represent planet migration that is halted via several mechanisms, including the interior 1:2 resonance with the magnetospheric disk truncation radius, the interior 1:2 resonance with the dust sublimation radius, and several scenarios for tidal halting. The models differ in the predicted power-law dependence of the exoplanet orbital semi-major axis as a function of stellarmore » mass, and thus we also include a power-law model with the exponent as a free parameter. We use a Bayesian analysis to assess the model success in reproducing empirical distributions of confirmed exoplanets and Kepler candidates that orbit interior to 0.1 AU. Our results confirm a correlation of the halting distance with stellar mass. Tidal halting provides the best fit to the empirical distribution of confirmed Jovian exoplanets at a statistically robust level, consistent with the Kozai mechanism and the spin-orbit misalignment of a substantial fraction of hot Jupiters. We can rule out migration halting at the interior 1:2 resonances with the magnetospheric disk truncation radius and the interior 1:2 resonance with the dust disk sublimation radius, a uniform random distribution, and a distribution with no dependence on stellar mass. Note that our results do not rule out Type-II migration, but rather eliminate the role of a circumstellar disk in stopping exoplanet migration. For Kepler candidates, which have a more restricted range in stellar mass compared to confirmed planets, we are unable to discern between the tidal dissipation and magnetospheric disk truncation braking mechanisms at a statistically significant level. The power-law model favors exponents in the

Design study of beam transport lines for BioLEIR facility at CERN

NASA Astrophysics Data System (ADS)

Ghithan, S.; Roy, G.; Schuh, S.

2017-09-01

The biomedical community has asked CERN to investigate the possibility to transform the Low Energy Ion Ring (LEIR) accelerator into a multidisciplinary, biomedical research facility (BioLEIR) that could provide ample, high-quality beams of a range of light ions suitable for clinically oriented, fundamental research on cell cultures and for radiation instrumentation development. The present LEIR machine uses fast beam extraction to the next accelerator in the chain, eventually leading to the Large Hadron Collider (LHC) . To provide beam for a biomedical research facility, a new slow extraction system must be installed. Two horizontal and one vertical experimental beamlines were designed for transporting the extracted beam to three experimental end-stations. The vertical beamline (pencil beam) was designed for a maximum energy of 75 MeV/u for low-energy radiobiological research, while the two horizontal beamlines could deliver up to 440 MeV/u. One horizontal beamline shall be used preferentially for biomedical experiments and shall provide pencil beam and a homogeneous broad beam, covering an area of 5 × 5 cm2 with a beam homogeneity of ±5%. The second horizontal beamline will have pencil beam only and is intended for hardware developments in the fields of (micro-)dosimetry and detector development. The minimum full aperture of the beamlines is approximately 100 mm at all magnetic elements, to accommodate the expected beam envelopes. Seven dipoles and twenty quadrupoles are needed for a total of 65 m of beamlines to provide the specified beams. In this paper we present the optical design for the three beamlines.

The CERN-EU high-energy reference field (CERF) facility for dosimetry at commercial flight altitudes and in space.

PubMed

Mitaroff, A; Cern, M Silari

2002-01-01

A reference facility for the calibration and intercomparison of active and passive detectors in broad neutron fields has been available at CERN since 1992. A positively charged hadron beam (a mixture of protons and pions) with momentum of 120 GeV/c hits a copper target, 50 cm thick and 7 cm in diameter. The secondary particles produced in the interaction traverse a shield, at 90 degrees with respect to the direction of the incoming beam. made of either 80 to 160 cm of concrete or 40 cm of iron. Behind the iron shield, the resulting neutron spectrum has a maximum at about 1 MeV, with an additional high-energy component. Behind the 80 cm concrete shield, the neutron spectrum has a second pronounced maximum at about 70 MeV and resembles the high-energy component of the radiation field created by cosmic rays at commercial flight altitudes. This paper describes the facility, reports on the latest neutron spectral measurements, gives an overview of the most important experiments performed by the various collaborating institutions over recent years and briefly addresses the possible application of the facility to measurements related to the space programme.

The HALT Polycystic Kidney Disease Trials: Design and Implementation

PubMed Central

Torres, Vicente E.; Perrone, Ronald D.; Steinman, Theodore I.; Bae, Kyongtae T.; Miller, J. Philip; Miskulin, Dana C.; Oskoui, Frederic Rahbari; Masoumi, Amirali; Hogan, Marie C.; Winklhofer, Franz T.; Braun, William; Thompson, Paul A.; Meyers, Catherine M.; Kelleher, Cass; Schrier, Robert W.

2010-01-01

Background and objectives: Two HALT PKD trials will investigate interventions that potentially slow kidney disease progression in hypertensive autosomal dominant polycystic kidney disease (ADPKD) patients. Studies were designed in early and later stages of ADPKD to assess the impact of intensive blockade of the renin-angiotensin-aldosterone system and level of BP control on progressive renal disease. Design, settings, participants, and measurements: PKD-HALT trials are multicenter, randomized, double-blind, placebo-controlled trials studying 1018 hypertensive ADPKD patients enrolled over 3 yr with 4 to 8 yr of follow-up. In study A, 548 participants, estimated GFR (eGFR) of >60 ml/min per 1.73 m2 were randomized to one of four arms in a 2-by-2 design: combination angiotensin converting enzyme inhibitor (ACEi) and angiotensin receptor blocker (ARB) therapy versus ACEi monotherapy at two levels of BP control. In study B, 470 participants, eGFR of 25 to 60 ml/min per 1.73 m2 compared ACEi/ARB therapy versus ACEi monotherapy, with BP control of 120 to 130/70 to 80 mmHg. Primary outcomes of studies A and B are MR-based percent change kidney volume and a composite endpoint of time to 50% reduction of baseline estimated eGFR, ESRD, or death, respectively. Results: This report describes design issues related to (1) novel endpoints such as kidney volume, (2) home versus office BP measures, and (3) the impact of RAAS inhibition on kidney and patient outcomes, safety, and quality of life. Conclusions: HALT PKD will evaluate potential benefits of rigorous BP control and inhibition of the renin-angiotensin-aldosterone system on kidney disease progression in ADPKD. PMID:20089507

Service management at CERN with Service-Now

NASA Astrophysics Data System (ADS)

Toteva, Z.; Alvarez Alonso, R.; Alvarez Granda, E.; Cheimariou, M.-E.; Fedorko, I.; Hefferman, J.; Lemaitre, S.; Clavo, D. Martin; Martinez Pedreira, P.; Pera Mira, O.

2012-12-01

The Information Technology (IT) and the General Services (GS) departments at CERN have decided to combine their extensive experience in support for IT and non-IT services towards a common goal - to bring the services closer to the end user based on Information Technology Infrastructure Library (ITIL) best practice. The collaborative efforts have so far produced definitions for the incident and the request fulfilment processes which are based on a unique two-dimensional service catalogue that combines both the user and the support team views of all services. After an extensive evaluation of the available industrial solutions, Service-now was selected as the tool to implement the CERN Service-Management processes. The initial release of the tool provided an attractive web portal for the users and successfully implemented two basic ITIL processes; the incident management and the request fulfilment processes. It also integrated with the CERN personnel databases and the LHC GRID ticketing system. Subsequent releases continued to integrate with other third-party tools like the facility management systems of CERN as well as to implement new processes such as change management. Independently from those new development activities it was decided to simplify the request fulfilment process in order to achieve easier acceptance by the CERN user community. We believe that due to the high modularity of the Service-now tool, the parallel design of ITIL processes e.g., event management and non-ITIL processes, e.g., computer centre hardware management, will be easily achieved. This presentation will describe the experience that we have acquired and the techniques that were followed to achieve the CERN customization of the Service-Now tool.

Hangout with CERN: a direct conversation with the public

NASA Astrophysics Data System (ADS)

Rao, Achintya; Goldfarb, Steven; Kahle, Kate

2016-04-01

Hangout with CERN refers to a weekly, half-hour-long, topical webcast hosted at CERN. The aim of the programme is threefold: (i) to provide a virtual tour of various locations and facilities at CERN, (ii) to discuss the latest scientific results from the laboratory, and, most importantly, (iii) to engage in conversation with the public and answer their questions. For each ;episode;, scientists gather around webcam-enabled computers at CERN and partner institutes/universities, connecting to one another using the Google+ social network's ;Hangouts; tool. The show is structured as a conversation mediated by a host, usually a scientist, and viewers can ask questions to the experts in real time through a Twitter hashtag or YouTube comments. The history of Hangout with CERN can be traced back to ICHEP 2012, where several physicists crowded in front of a laptop connected to Google+, using a ;Hangout On Air; webcast to explain to the world the importance of the discovery of the Higgs-like boson, announced just two days before at the same conference. Hangout with CERN has also drawn inspiration from two existing outreach endeavours: (i) ATLAS Virtual Visits, which connected remote visitors with scientists in the ATLAS Control Room via video conference, and (ii) the Large Hangout Collider, in which CMS scientists gave underground tours via Hangouts to groups of schools and members of the public around the world. In this paper, we discuss the role of Hangout with CERN as a bi-directional outreach medium and an opportunity to train scientists in effective communication.

Instrument intercomparison in the high-energy mixed field at the CERN-EU reference field (CERF) facility.

PubMed

Caresana, Marco; Helmecke, Manuela; Kubancak, Jan; Manessi, Giacomo Paolo; Ott, Klaus; Scherpelz, Robert; Silari, Marco

2014-10-01

This paper discusses an intercomparison campaign performed in the mixed radiation field at the CERN-EU (CERF) reference field facility. Various instruments were employed: conventional and extended-range rem counters including a novel instrument called LUPIN, a bubble detector using an active counting system (ABC 1260) and two tissue-equivalent proportional counters (TEPCs). The results show that the extended range instruments agree well within their uncertainties and within 1σ with the H*(10) FLUKA value. The conventional rem counters are in good agreement within their uncertainties and underestimate H*(10) as measured by the extended range instruments and as predicted by FLUKA. The TEPCs slightly overestimate the FLUKA value but they are anyhow consistent with it when taking the comparatively large total uncertainties into account, and indicate that the non-neutron part of the stray field accounts for ∼30 % of the total H*(10). © The Author 2013. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Designing and Evaluating Interventions to Halt the Transmission of Tuberculosis.

PubMed

Dowdy, David W; Grant, Alison D; Dheda, Keertan; Nardell, Edward; Fielding, Katherine; Moore, David A J

2017-11-03

To reduce the incidence of tuberculosis, it is insufficient to simply understand the dynamics of tuberculosis transmission. Rather, we must design and rigorously evaluate interventions to halt transmission, prioritizing those interventions most likely to achieve population-level impact. Synergy in reducing tuberculosis transmission may be attainable by combining interventions that shrink the reservoir of latent Mycobacterium tuberculosis infection (preventive therapy), shorten the time between disease onset and treatment initiation (case finding and diagnosis), and prevent transmission in key settings, such as the built environment (infection control). In evaluating efficacy and estimating population-level impact, cluster-randomized trials and mechanistic models play particularly prominent roles. Historical and contemporary evidence suggests that effective public health interventions can halt tuberculosis transmission, but an evidence-based approach based on knowledge of local epidemiology is necessary for success. We provide a roadmap for designing, evaluating, and modeling interventions to interrupt the process of transmission that fuels a diverse array of tuberculosis epidemics worldwide. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.

Sharing scientific discovery globally: toward a CERN virtual visit service

NASA Astrophysics Data System (ADS)

Goldfarb, S.; Hatzifotiadou, D.; Lapka, M.; Papanestis, A.

2017-10-01

The installation of virtual visit services by the LHC collaborations began shortly after the first high-energy collisions were provided by the CERN accelerator in 2010. The experiments: ATLAS [1], CMS [2], LHCb [3], and ALICE [4] have all joined in this popular and effective method to bring the excitement of scientific exploration and discovery into classrooms and other public venues around the world. Their programmes, which use a combination of video conference, webcast, and video recording to communicate with remote audiences have already reached tens of thousands of viewers, and the demand only continues to grow. Other venues, such as the CERN Control Centre, are also considering similar permanent installations. We present a summary of the development of the various systems in use around CERN today, including the technology deployed and a variety of use cases. We then lay down the arguments for the creation of a CERN-wide service that would support these programmes in a more coherent and effective manner. Potential services include a central booking system and operational management similar to what is currently provided for the common CERN video conference facilities. Certain choices in technology could be made to support programmes based on popular tools including (but not limited to) Skype™ [5], Google Hangouts [6], Facebook Live [7], and Periscope [8]. Successful implementation of the project, which relies on close partnership between the experiments, CERN IT CDA [9], and CERN IR ECO [10], has the potential to reach an even larger, global audience, more effectively than ever before.

Halting the fuse discharge propagation using optical fiber microwires.

PubMed

Rocha, A M; Fernandes, G; Domingues, F; Niehus, M; Pinto, A N; Facão, M; André, P S

2012-09-10

We report and analyze the halting of the fuse effect propagation in optical fiber microwires. The increase of the mode field diameter in the tapered region decreases the optical intensity resulting in the extinction of the fuse effect. This fiber element presents a low insertion loss and can be introduced in the optical network in order to protect the active equipment from the damage caused by the fuse effect.

Upgrade of the cryogenic infrastructure of SM18, CERN main test facility for superconducting magnets and RF cavities

NASA Astrophysics Data System (ADS)

Perin, A.; Dhalla, F.; Gayet, P.; Serio, L.

2017-12-01

SM18 is CERN main facility for testing superconducting accelerator magnets and superconducting RF cavities. Its cryogenic infrastructure will have to be significantly upgraded in the coming years, starting in 2019, to meet the testing requirements for the LHC High Luminosity project and for the R&D program for superconducting magnets and RF equipment until 2023 and beyond. This article presents the assessment of the cryogenic needs based on the foreseen test program and on past testing experience. The current configuration of the cryogenic infrastructure is presented and several possible upgrade scenarios are discussed. The chosen upgrade configuration is then described and the characteristics of the main newly required cryogenic equipment, in particular a new 35 g/s helium liquefier, are presented. The upgrade implementation strategy and plan to meet the required schedule are then described.

Eliminating the Rhetoric: An Evaluation of the Halt Phase Strategy

DTIC Science & Technology

1999-06-01

Halt operations can demonstrate to the enemy leadership that continued aggression equals unacceptable risk because air superiority can be exploited...lesson can be drawn. The presence of ground forces demonstrates commitment and leadership . Powerful ground combat forces represent the strongest... leadership far more than technology will determine who wins and who loses." 10 The Fallacy of Technological Determinism Another main theme in critiques of

Hydrodynamic Tunneling of 440 GeV SPS protons in Solid Material: Production of Warm Dense Matter at CERN HiRadMat Facility

NASA Astrophysics Data System (ADS)

Tahir, Naeem Ahmad; Blanco Sancho, Juan; Schmidt, Ruediger; Shutov, Alaxander; Burkart, Florian; Wollmann, Daniel; Piriz, Antonio Roberto

2013-10-01

Numerical simulations have shown that the range of 7 TeV LHC protons in solid matter will be significantly increased due to hydrodynamic tunneling. For example, in solid copper and solid carbon, these protons and the shower can penetrate up to 35 m and 25 m, respectively. However, their corresponding static range in the two materials is 1 m and 3 m, respectively. This will have important implications on machine protection design. In order to validate these simulation results, experiments have been performed at the CERN HiRadMat facility using the 440 GeV SPS proton beam irradiating solid copper cylindrical target. The phenomenon of hydrodynamic tunneling has been experimentally confirmed and good agreement has been found between the simulations and the experimental results. A very interesting outcome of this work is that the HiRadMat facility can be used to generate High Energy Density matter including Warm Dense Matter and strongly coupled plasmas in the laboratory.

Thermostructural characterization and structural elastic property optimization of novel high luminosity LHC collimation materials at CERN

NASA Astrophysics Data System (ADS)

Borg, M.; Bertarelli, A.; Carra, F.; Gradassi, P.; Guardia-Valenzuela, J.; Guinchard, M.; Izquierdo, G. Arnau; Mollicone, P.; Sacristan-de-Frutos, O.; Sammut, N.

2018-03-01

The CERN Large Hadron Collider is currently being upgraded to operate at a stored beam energy of 680 MJ through the High Luminosity upgrade. The LHC performance is dependent on the functionality of beam collimation systems, essential for safe beam cleaning and machine protection. A dedicated beam experiment at the CERN High Radiation to Materials facility is created under the HRMT-23 experimental campaign. This experiment investigates the behavior of three collimation jaws having novel composite absorbers made of copper diamond, molybdenum carbide graphite, and carbon fiber carbon, experiencing accidental scenarios involving the direct beam impact on the material. Material characterization is imperative for the design, execution, and analysis of such experiments. This paper presents new data and analysis of the thermostructural characteristics of some of the absorber materials commissioned within CERN facilities. In turn, characterized elastic properties are optimized through the development and implementation of a mixed numerical-experimental optimization technique.

High energy beam impact tests on a LHC tertiary collimator at the CERN high-radiation to materials facility

NASA Astrophysics Data System (ADS)

Cauchi, Marija; Aberle, O.; Assmann, R. W.; Bertarelli, A.; Carra, F.; Cornelis, K.; Dallocchio, A.; Deboy, D.; Lari, L.; Redaelli, S.; Rossi, A.; Salvachua, B.; Mollicone, P.; Sammut, N.

2014-02-01

The correct functioning of a collimation system is crucial to safely operate highly energetic particle accelerators, such as the Large Hadron Collider (LHC). The requirements to handle high intensity beams can be demanding. In this respect, investigating the consequences of LHC particle beams hitting tertiary collimators (TCTs) in the experimental regions is a fundamental issue for machine protection. An experimental test was designed to investigate the robustness and effects of beam accidents on a fully assembled collimator, based on accident scenarios in the LHC. This experiment, carried out at the CERN High-Radiation to Materials (HiRadMat) facility, involved 440 GeV proton beam impacts of different intensities on the jaws of a horizontal TCT. This paper presents the experimental setup and the preliminary results obtained, together with some first outcomes from visual inspection and a comparison of such results with numerical simulations.

Effect of Post-HALT Annealing on Leakage Currents in Solid Tantalum Capacitors

NASA Technical Reports Server (NTRS)

Teverovsky, Alexander

2010-01-01

Degradation of leakage currents is often observed during life testing of tantalum capacitors and is sometimes attributed to the field-induced crystallization in amorphous anodic tantalum pentoxide dielectrics. However, degradation of leakage currents and the possibility of annealing of degraded capacitors have not been investigated yet. In this work the effect of annealing after highly accelerated life testing (HALT) on leakage currents in various types of solid tantalum capacitors was analyzed. Variations of leakage currents with time during annealing at temperatures from 125 oC to 180 oC, thermally stimulated depolarization (TSD) currents, and I-V characteristics were measured to understand the conduction mechanism and the reason for current degradation. Annealing resulted in a gradual decrease of leakage currents and restored their initial values. Repeat HALT after annealing resulted in reproducible degradation of leakage currents. The observed results are explained based on ionic charge instability (drift/diffusion of oxygen vacancies) in the tantalum pentoxide dielectrics using a modified Schottky conduction mechanism.

Halting a Runaway Train: Reforming Teacher Pensions for the 21st Century

ERIC Educational Resources Information Center

Lafferty, Michael B.

2011-01-01

When it comes to public-sector pensions, writes lead author Michael B. Lafferty in this report, "A major public-policy (and public-finance) problem has been defined and measured, debated and deliberated, but not yet solved. Except where it has been." As recounted in "Halting a Runaway Train: Reforming Teacher Pensions for the 21st…

Formation of a uniform ion beam using octupole magnets for BioLEIR facility at CERN

NASA Astrophysics Data System (ADS)

Amin, T.; Barlow, R.; Ghithan, S.; Roy, G.; Schuh, S.

2018-04-01

The possibility to transform the Low Energy Ion Ring (LEIR) accelerator at CERN into a multidisciplinary, biomedical research facility (BioLEIR) was investigated based on a request from the biomedical community. BioLEIR aims to provide a unique facility with a range of fully stripped ion beams (e.g. He, Li, Be, B, C, N, O) and energies suitable for multidisciplinary biomedical, clinically-oriented research. Two horizontal and one vertical beam transport lines have been designed for transporting the extracted beam from LEIR to three experimental end-stations. The vertical beamline was designed for a maximum energy of 75 MeV/u, while the two horizontal beamlines shall deliver up to a maximum energy of 440 MeV/u. A pencil beam of 4.3 mm FWHM (Full Width Half Maximum) as well as a homogeneous broad beam of 40 × 40 mm2, with a beam homogeneity better than ±4%, are available at the first horizontal (H1) irradiation point, while only a pencil beam is available at the second horizontal (H2) and vertical (V) irradiation points. The H1 irradiation point shall be used to conduct systematic studies of the radiation effect from different ion species on cell-lines. The H1 beamline was designed to utilize two octupole magnets which transform the Gaussian beam distribution at the target location into an approximately uniformly distributed rectangular beam. In this paper, we report on the multi-particle tracking calculations performed using MAD-X software suite for the H1 beam optics to arrive at a homogeneous broad beam on target using nonlinear focusing techniques, and on those to create a Gaussian pencil beam on target by adjusting quadrupoles strengths and positions.

Measurement of the radiative capture cross section of the s-process branching points 204Tl and 171Tm at the n_TOF facility (CERN)

NASA Astrophysics Data System (ADS)

Casanovas, A.; Domingo-Pardo, C.; Guerrero, C.; Lerendegui-Marco, J.; Calviño, F.; Tarifeño-Saldivia, A.; Dressler, R.; Heinitz, S.; Kivel, N.; Quesada, J. M.; Schumann, D.; Aberle, O.; Alcayne, V.; Andrzejewski, J.; Audouin, L.; Bécares, V.; Bacak, M.; Barbagallo, M.; Bečvář, F.; Bellia, G.; Berthoumieux, E.; Billowes, J.; Bosnar, D.; Brown, A.; Busso, M.; Caamaño, M.; Caballero-Ontanaya, L.; Calviani, M.; Cano-Ott, D.; Cerutti, F.; Chen, Y. H.; Chiaveri, E.; Colonna, N.; Cortés, G.; Cortés-Giraldo, M. A.; Cosentino, L.; Cristallo, S.; Damone, L. A.; Diakaki, M.; Dietz, M.; Dupont, E.; Durán, I.; Eleme, Z.; Fernández-Domínguez, B.; Ferrari, A.; Ferreira, P.; Finocchiaro, P.; Furman, V.; Göbel, K.; Gawlik, A.; Gilardoni, S.; Glodariu, T.; Gonçalves, I. F.; González-Romero, E.; Gunsing, F.; Heyse, J.; Jenkins, D. G.; Käppeler, F.; Kadi, Y.; Katabuchi, T.; Kimura, A.; Kokkoris, M.; Kopatch, Y.; Krtička, M.; Kurtulgil, D.; Ladarescu, I.; Lederer-Woods, C.; Meo, S. Lo; Lonsdale, S. J.; Macina, D.; Martínez, T.; Masi, A.; Massimi, C.; Mastinu, P.; Mastromarco, M.; Matteucci, F.; Maugeri, E. A.; Mazzone, A.; Mendoza, E.; Mengoni, A.; Michalopoulou, V.; Milazzo, P. M.; Mingrone, F.; Musumarra, A.; Negret, A.; Nolte, R.; Ogállar, F.; Oprea, A.; Patronis, N.; Pavlik, A.; Perkowski, J.; Persanti, L.; Porras, I.; Praena, J.; Radeck, D.; Ramos, D.; Rauscher, T.; Reifarth, R.; Rochman, D.; Sabaté-Gilarte, M.; Saxena, A.; Schillebeeckx, P.; Simone, S.; Smith, A. G.; Sosnin, N. V.; Stamatopoulos, A.; Tagliente, G.; Tain, J. L.; Talip, T.; Tassan-Got, L.; Tsinganis, A.; Ulrich, J.; Valenta, S.; Vannini, G.; Variale, V.; Vaz, P.; Ventura, A.; Vlachoudis, V.; Vlastou, R.; Wallner, A.; Woods, P. J.; Wright, T.; Žugec, P.; Köster, U.

2018-05-01

The neutron capture cross section of some unstable nuclei is especially relevant for s-process nucleosynthesis studies. This magnitude is crucial to determine the local abundance pattern, which can yield valuable information of the s-process stellar environment. In this work we describe the neutron capture (n,γ) measurement on two of these nuclei of interest, 204Tl and 171Tm, from target production to the final measurement, performed successfully at the n_TOF facility at CERN in 2014 and 2015. Preliminary results on the ongoing experimental data analysis will also be shown. These results include the first ever experimental observation of capture resonances for these two nuclei.

The Proton Synchrotron (PS): At the Core of the CERN Accelerators

NASA Astrophysics Data System (ADS)

Cundy, Donald; Gilardoni, Simone

The following sections are included: * Introduction * Extraction: Getting the Beam to Leave the Accelerator * Acceleration and Bunch Gymnastics * Boosting PS Beam Intensity * Capacitive Energy Storage Replaces Flywheel * Taking the Neutrinos by the Horns * OMEGA: Towards the Electronic Bubble Chamber * ISOLDE: Targeting a New Era in Nuclear Physics * The CERN n_TOF Facility: Catching Neutrons on the Fly * References

Going It Alone: Can California's K-12 School Districts Adequately and Equitably Fund School Facilities? Policy Research Brief

ERIC Educational Resources Information Center

Center for Cities & Schools, 2015

2015-01-01

After\tdecades of dedicated investment, state funding to assist local California school districts in the construction, modernization, and maintenance of their school facilities has come to a halt. As the Governor, the legislature, and other stakeholders debate the future of the state's K-12 school facility funding role, a big unknown exists:…

Signature CERN-URSS

ScienceCinema

None

2017-12-09

Le DG W.Jentschke souhaite la bienvenue à l'assemblée et aux invités pour la signature du protocole entre le Cern et l'URSS qui est un événement important. C'est en 1955 que 55 visiteurs soviétiques ont visité le Cern pour la première fois. Le premier DG au Cern, F.Bloch, et Mons.Amaldi sont aussi présents. Tandis que le discours anglais de W.Jentschke est traduit en russe, le discours russe de Mons.Morozov est traduit en anglais.

Preparation and characterization of 33S samples for 33S(n, α)30Si cross-section measurements at the n_TOF facility at CERN

NASA Astrophysics Data System (ADS)

Praena, J.; Ferrer, F. J.; Vollenberg, W.; Sabaté-Gilarte, M.; Fernández, B.; García-López, J.; Porras, I.; Quesada, J. M.; Altstadt, S.; Andrzejewski, J.; Audouin, L.; Bécares, V.; Barbagallo, M.; Bečvář, F.; Belloni, F.; Berthoumieux, E.; Billowes, J.; Boccone, V.; Bosnar, D.; Brugger, M.; Calviño, F.; Calviani, M.; Cano-Ott, D.; Carrapiço, C.; Cerutti, F.; Chiaveri, E.; Chin, M.; Colonna, N.; Cortés, G.; Cortés-Giraldo, M. A.; Diakaki, M.; Dietz, M.; Domingo-Pardo, C.; Dressler, R.; Durán, I.; Eleftheriadis, C.; Ferrari, A.; Fraval, K.; Furman, V.; Göbel, K.; Gómez-Hornillos, M. B.; Ganesan, S.; García, A. R.; Giubrone, G.; Gonçalves, I. F.; González-Romero, E.; Goverdovski, A.; Griesmayer, E.; Guerrero, C.; Gunsing, F.; Heftrich, T.; Hernández-Prieto, A.; Heyse, J.; Jenkins, D. G.; Jericha, E.; Käppeler, F.; Kadi, Y.; Karadimos, D.; Katabuchi, T.; Ketlerov, V.; Khryachkov, V.; Kivel, N.; Koehler, P.; Kokkoris, M.; Kroll, J.; Krtička, M.; Lampoudis, C.; Langer, C.; Leal-Cidoncha, E.; Lederer, C.; Leeb, H.; Leong, L. S.; Lerendegui-Marco, J.; Losito, R.; Mallick, A.; Manousos, A.; Marganiec, J.; Martínez, T.; Massimi, C.; Mastinu, P.; Mastromarco, M.; Mendoza, E.; Mengoni, A.; Milazzo, P. M.; Mingrone, F.; Mirea, M.; Mondelaers, W.; Paradela, C.; Pavlik, A.; Perkowski, J.; Plompen, A. J. M.; Rauscher, T.; Reifarth, R.; Riego-Perez, A.; Robles, M.; Rubbia, C.; Ryan, J. A.; Sarmento, R.; Saxena, A.; Schillebeeckx, P.; Schmidt, S.; Schumann, D.; Sedyshev, P.; Tagliente, G.; Tain, J. L.; Tarifeño-Saldivia, A.; Tarrío, D.; Tassan-Got, L.; Tsinganis, A.; Valenta, S.; Vannini, G.; Variale, V.; Vaz, P.; Ventura, A.; Vermeulen, M. J.; Vlachoudis, V.; Vlastou, R.; Wallner, A.; Ware, T.; Weigand, M.; Weiss, C.; Wright, T.; Žugec, P.; n TOF Collaboration

2018-05-01

Thin 33S samples for the study of the 33S(n, α)30Si cross-section at the n_TOF facility at CERN were made by thermal evaporation of 33S powder onto a dedicated substrate made of kapton covered with thin layers of copper, chromium and titanium. This method has provided for the first time bare sulfur samples a few centimeters in diameter. The samples have shown an excellent adherence with no mass loss after few years and no sublimation in vacuum at room temperature. The determination of the mass thickness of 33S has been performed by means of Rutherford backscattering spectrometry. The samples have been successfully tested under neutron irradiation.

Going It Alone: Can California's K-12 School Districts Adequately and Equitably Fund School Facilities? Policy Research Working Paper

ERIC Educational Resources Information Center

Vincent, Jeffrey M.; Jain, Liz S.

2015-01-01

After\tmore\tthan a decade of dedicated investment, state funding to assist local California school\tdistricts in the construction, modernization, and maintenance of their school facilities has come to a halt. As the Governor, the legislature, and other stakeholders debate the future of the state's K-12 school facility funding role, a big unknown…

A facility to search for hidden particles at the CERN SPS: the SHiP physics case.

PubMed

Alekhin, Sergey; Altmannshofer, Wolfgang; Asaka, Takehiko; Batell, Brian; Bezrukov, Fedor; Bondarenko, Kyrylo; Boyarsky, Alexey; Choi, Ki-Young; Corral, Cristóbal; Craig, Nathaniel; Curtin, David; Davidson, Sacha; de Gouvêa, André; Dell'Oro, Stefano; deNiverville, Patrick; Bhupal Dev, P S; Dreiner, Herbi; Drewes, Marco; Eijima, Shintaro; Essig, Rouven; Fradette, Anthony; Garbrecht, Björn; Gavela, Belen; Giudice, Gian F; Goodsell, Mark D; Gorbunov, Dmitry; Gori, Stefania; Grojean, Christophe; Guffanti, Alberto; Hambye, Thomas; Hansen, Steen H; Helo, Juan Carlos; Hernandez, Pilar; Ibarra, Alejandro; Ivashko, Artem; Izaguirre, Eder; Jaeckel, Joerg; Jeong, Yu Seon; Kahlhoefer, Felix; Kahn, Yonatan; Katz, Andrey; Kim, Choong Sun; Kovalenko, Sergey; Krnjaic, Gordan; Lyubovitskij, Valery E; Marcocci, Simone; Mccullough, Matthew; McKeen, David; Mitselmakher, Guenakh; Moch, Sven-Olaf; Mohapatra, Rabindra N; Morrissey, David E; Ovchynnikov, Maksym; Paschos, Emmanuel; Pilaftsis, Apostolos; Pospelov, Maxim; Reno, Mary Hall; Ringwald, Andreas; Ritz, Adam; Roszkowski, Leszek; Rubakov, Valery; Ruchayskiy, Oleg; Schienbein, Ingo; Schmeier, Daniel; Schmidt-Hoberg, Kai; Schwaller, Pedro; Senjanovic, Goran; Seto, Osamu; Shaposhnikov, Mikhail; Shchutska, Lesya; Shelton, Jessie; Shrock, Robert; Shuve, Brian; Spannowsky, Michael; Spray, Andy; Staub, Florian; Stolarski, Daniel; Strassler, Matt; Tello, Vladimir; Tramontano, Francesco; Tripathi, Anurag; Tulin, Sean; Vissani, Francesco; Winkler, Martin W; Zurek, Kathryn M

2016-12-01

This paper describes the physics case for a new fixed target facility at CERN SPS. The SHiP (search for hidden particles) experiment is intended to hunt for new physics in the largely unexplored domain of very weakly interacting particles with masses below the Fermi scale, inaccessible to the LHC experiments, and to study tau neutrino physics. The same proton beam setup can be used later to look for decays of tau-leptons with lepton flavour number non-conservation, [Formula: see text] and to search for weakly-interacting sub-GeV dark matter candidates. We discuss the evidence for physics beyond the standard model and describe interactions between new particles and four different portals-scalars, vectors, fermions or axion-like particles. We discuss motivations for different models, manifesting themselves via these interactions, and how they can be probed with the SHiP experiment and present several case studies. The prospects to search for relatively light SUSY and composite particles at SHiP are also discussed. We demonstrate that the SHiP experiment has a unique potential to discover new physics and can directly probe a number of solutions of beyond the standard model puzzles, such as neutrino masses, baryon asymmetry of the Universe, dark matter, and inflation.

Best Practices for Controlling Tuberculosis-Training in Correctional Facilities: A Mixed Methods Evaluation

ERIC Educational Resources Information Center

Murray, Ellen R.

2016-01-01

According to the literature, identifying and treating tuberculosis (TB) in correctional facilities have been problematic for the inmates and also for the communities into which inmates are released. The importance of training those who can identify this disease early into incarceration is vital to halt the transmission. Although some training has…

Ni62(n,γ) and Ni63(n,γ) cross sections measured at the n_TOF facility at CERN

NASA Astrophysics Data System (ADS)

Lederer, C.; Massimi, C.; Berthoumieux, E.; Colonna, N.; Dressler, R.; Guerrero, C.; Gunsing, F.; Käppeler, F.; Kivel, N.; Pignatari, M.; Reifarth, R.; Schumann, D.; Wallner, A.; Altstadt, S.; Andriamonje, S.; Andrzejewski, J.; Audouin, L.; Barbagallo, M.; Bécares, V.; Bečvář, F.; Belloni, F.; Berthier, B.; Billowes, J.; Boccone, V.; Bosnar, D.; Brugger, M.; Calviani, M.; Calviño, F.; Cano-Ott, D.; Carrapiço, C.; Cerutti, F.; Chiaveri, E.; Chin, M.; Cortés, G.; Cortés-Giraldo, M. A.; Dillmann, I.; Domingo-Pardo, C.; Duran, I.; Dzysiuk, N.; Eleftheriadis, C.; Fernández-Ordóñez, M.; Ferrari, A.; Fraval, K.; Ganesan, S.; García, A. R.; Giubrone, G.; Gómez-Hornillos, M. B.; Gonçalves, I. F.; González-Romero, E.; Gramegna, F.; Griesmayer, E.; Gurusamy, P.; Harrisopulos, S.; Heil, M.; Ioannides, K.; Jenkins, D. G.; Jericha, E.; Kadi, Y.; Karadimos, D.; Korschinek, G.; Krtička, M.; Kroll, J.; Langer, C.; Lebbos, E.; Leeb, H.; Leong, L. S.; Losito, R.; Lozano, M.; Manousos, A.; Marganiec, J.; Marrone, S.; Martinez, T.; Mastinu, P. F.; Mastromarco, M.; Meaze, M.; Mendoza, E.; Mengoni, A.; Milazzo, P. M.; Mingrone, F.; Mirea, M.; Mondalaers, W.; Paradela, C.; Pavlik, A.; Perkowski, J.; Plag, R.; Plompen, A.; Praena, J.; Quesada, J. M.; Rauscher, T.; Riego, A.; Roman, F.; Rubbia, C.; Sarmento, R.; Schillebeeckx, P.; Schmidt, S.; Tagliente, G.; Tain, J. L.; Tarrío, D.; Tassan-Got, L.; Tsinganis, A.; Tlustos, L.; Valenta, S.; Vannini, G.; Variale, V.; Vaz, P.; Ventura, A.; Vermeulen, M. J.; Versaci, R.; Vlachoudis, V.; Vlastou, R.; Ware, T.; Weigand, M.; Weiß, C.; Wright, T. J.; Žugec, P.; n TOF Collaboration

2014-02-01

The cross section of the Ni62(n,γ) reaction was measured with the time-of-flight technique at the neutron time-of-flight facility n_TOF at CERN. Capture kernels of 42 resonances were analyzed up to 200 keV neutron energy and Maxwellian averaged cross sections (MACS) from kT = 5-100 keV were calculated. With a total uncertainty of 4.5%, the stellar cross section is in excellent agreement with the the KADoNiS compilation at kT=30 keV, while being systematically lower up to a factor of 1.6 at higher stellar temperatures. The cross section of the Ni63(n ,γ) reaction was measured for the first time at n_TOF. We determined unresolved cross sections from 10 to 270 keV with a systematic uncertainty of 17%. These results provide fundamental constraints on s-process production of heavier species, especially the production of Cu in massive stars, which serve as the dominant source of Cu in the solar system.

Measurement and analysis of the 241Am neutron capture cross section at the n_TOF facility at CERN

NASA Astrophysics Data System (ADS)

Mendoza, E.; Cano-Ott, D.; Altstadt, S.; Andriamonje, S.; Andrzejewski, J.; Audouin, L.; Balibrea, J.; Bécares, V.; Barbagallo, M.; Bečvář, F.; Belloni, F.; Berthier, B.; Berthoumieux, E.; Billowes, J.; Bosnar, D.; Brugger, M.; Calviño, F.; Calviani, M.; Carrapiço, C.; Cerutti, F.; Chiaveri, E.; Chin, M.; Colonna, N.; Cortés, G.; Cortés-Giraldo, M. A.; Diakaki, M.; Dillmann, I.; Domingo-Pardo, C.; Durán, I.; Dzysiuk, N.; Eleftheriadis, C.; Ferrari, A.; Fraval, K.; Furman, V.; Gómez-Hornillos, M. B.; Ganesan, S.; García, A. R.; Giubrone, G.; Gonçalves, I. F.; González, E.; Goverdovski, A.; Gramegna, F.; Griesmayer, E.; Guerrero, C.; Gunsing, F.; Gurusamy, P.; Heftrich, T.; Heinitz, S.; Hernández-Prieto, A.; Heyse, J.; Jenkins, D. G.; Jericha, E.; Käppeler, F.; Kadi, Y.; Karadimos, D.; Katabuchi, T.; Ketlerov, V.; Khryachkov, V.; Koehler, P.; Kokkoris, M.; Kroll, J.; Krtička, M.; Lampoudis, C.; Langer, C.; Leal-Cidoncha, E.; Lederer, C.; Leeb, H.; Leong, L. S.; Lerendegui-Marco, J.; Licata, M.; López, D.; Losito, R.; Manousos, A.; Marganiec, J.; Martínez, T.; Massimi, C.; Mastinu, P.; Mastromarco, M.; Mengoni, A.; Milazzo, P. M.; Mingrone, F.; Mirea, M.; Mondelaers, W.; Paradela, C.; Pavlik, A.; Perkowski, J.; Plompen, A. J. M.; Praena, J.; Quesada, J. M.; Rauscher, T.; Reifarth, R.; Riego-Perez, A.; Robles, M.; Roman, F.; Rubbia, C.; Ryan, J. A.; Sabaté-Gilarte, M.; Sarmento, R.; Saxena, A.; Schillebeeckx, P.; Schmidt, S.; Schumann, D.; Sedyshev, P.; Tagliente, G.; Tain, J. L.; Tarifeño-Saldivia, A.; Tarrío, D.; Tassan-Got, L.; Tsinganis, A.; Valenta, S.; Vannini, G.; Variale, V.; Vaz, P.; Ventura, A.; Vermeulen, M. J.; Versaci, R.; Vlachoudis, V.; Vlastou, R.; Wallner, A.; Ware, T.; Weigand, M.; Weiss, C.; Wright, T.; Žugec, P.; n TOF Collaboration

2018-05-01

The 241Am(n ,γ ) cross section has been measured at the n_TOF facility at CERN with the n_TOF BaF2 Total Absorption Calorimeter in the energy range between 0.2 eV and 10 keV. Our results are analyzed as resolved resonances up to 700 eV, allowing a more detailed description of the cross section than in the current evaluations, which contain resolved resonances only up to 150-160 eV. The cross section in the unresolved resonance region is perfectly consistent with the predictions based on the average resonance parameters deduced from the resolved resonances, thus obtaining a consistent description of the cross section in the full neutron energy range under study. Below 20 eV, our results are in reasonable agreement with JEFF-3.2 as well as with the most recent direct measurements of the resonance integral, and differ up to 20-30% with other experimental data. Between 20 eV and 1 keV, the disagreement with other experimental data and evaluations gradually decreases, in general, with the neutron energy. Above 1 keV, we find compatible results with previously existing values.

Manufacture of Autologous CD34+ Selected Grafts in the NIAID-Sponsored HALT-MS and SCOT Multicenter Clinical Trials for Autoimmune Diseases.

PubMed

Keever-Taylor, Carolyn A; Heimfeld, Shelly; Steinmiller, Kaitlyn C; Nash, Richard A; Sullivan, Keith M; Czarniecki, Christine W; Granderson, Tomeka C; Goldstein, Julia S; Griffith, Linda M

2017-09-01

To ensure comparable grafts for autologous hematopoietic cell transplantation (HCT) in the National Institute of Allergy and Infectious Diseases-sponsored Investigational New Drug protocols for multiple sclerosis (HALT-MS) and systemic sclerosis (SCOT), a Drug Master File approach to control manufacture was implemented, including a common Master Production Batch Record and site-specific standard operating procedures with "Critical Elements." We assessed comparability of flow cytometry and controlled rate cryopreservation among sites and stability of cryopreserved grafts using hematopoietic progenitor cells (HPCs) from healthy donors. Hematopoietic Progenitor Cells, Apheresis-CD34+ Enriched, for Autologous Use (Auto-CD34 + HPC) graft specifications included ≥70% viable CD34 + cells before cryopreservation. For the 2 protocols, 110 apheresis collections were performed; 121 lots of Auto-CD34 + HPC were cryopreserved, and 107 of these (88.4%) met release criteria. Grafts were infused at a median of 25 days (range, 17 to 68) post-apheresis for HALT-MS (n = 24), and 25 days (range, 14 to 78) for SCOT (n = 33). Subjects received precryopreservation doses of a median 5.1 × 10 6 viable CD34 + cells/kg (range, 3.9 to 12.8)  for HALT-MS and 5.6 × 10 6 viable CD34 + cells/kg (range, 2.6 to 10.2) for SCOT. Recovery of granulocytes occurred at a median of 11 days (range, 9 to 15) post-HCT for HALT-MS and 10 days (range, 8 to 12) for SCOT, independent of CD34 + cell dose. Subjects received their last platelet transfusion at a median of 9 days (range, 6 to 16) for HALT-MS and 8 days (range, 6 to 23) for SCOT; higher CD34 + /kg doses were associated with faster platelet recovery. Stability testing of cryopreserved healthy donor CD34 + HPCs over 6 months of vapor phase liquid nitrogen storage demonstrated consistent 69% to 73% recovery of viable CD34 + cells. Manufacturing of Auto-CD34 + HPC for the HALT-MS and SCOT protocols was comparable across all sites and

CERN welcomes new members

NASA Astrophysics Data System (ADS)

2017-08-01

Lithuania is on course to become an associate member of CERN, pending final approval by the Lithuanian parliament. Associate membership will allow representatives of the Baltic nation to take part in meetings of the CERN Council, which oversees the Geneva-based physics lab.

Introduction to CERN

ScienceCinema

Heuer, R.-D.

2018-02-19

Summer Student Lecture Programme Introduction. The mission of CERN; push back the frontiers of knowledge, e.g. the secrets of the Big Bang...what was the matter like within the first moments of the Universe's existence? You have to develop new technologies for accelerators and detectors (also information technology--the Web and the GRID and medicine--diagnosis and therapy). There are three key technology areas at CERN; accelerating, particle detection, large-scale computing.

Scaling the CERN OpenStack cloud

NASA Astrophysics Data System (ADS)

Bell, T.; Bompastor, B.; Bukowiec, S.; Castro Leon, J.; Denis, M. K.; van Eldik, J.; Fermin Lobo, M.; Fernandez Alvarez, L.; Fernandez Rodriguez, D.; Marino, A.; Moreira, B.; Noel, B.; Oulevey, T.; Takase, W.; Wiebalck, A.; Zilli, S.

2015-12-01

CERN has been running a production OpenStack cloud since July 2013 to support physics computing and infrastructure services for the site. In the past year, CERN Cloud Infrastructure has seen a constant increase in nodes, virtual machines, users and projects. This paper will present what has been done in order to make the CERN cloud infrastructure scale out.

Rare beneficial mutations can halt Muller's ratchet

NASA Astrophysics Data System (ADS)

Balick, Daniel; Goyal, Sidhartha; Jerison, Elizabeth; Neher, Richard; Shraiman, Boris; Desai, Michael

2012-02-01

In viral, bacterial, and other asexual populations, the vast majority of non-neutral mutations are deleterious. This motivates the application of models without beneficial mutations. Here we show that the presence of surprisingly few compensatory mutations halts fitness decay in these models. Production of deleterious mutations is balanced by purifying selection, stabilizing the fitness distribution. However, stochastic vanishing of fitness classes can lead to slow fitness decay (i.e. Muller's ratchet). For weakly deleterious mutations, production overwhelms purification, rapidly decreasing population fitness. We show that when beneficial mutations are introduced, a stable steady state emerges in the form of a dynamic mutation-selection balance. We argue this state is generic for all mutation rates and population sizes, and is reached as an end state as genomes become saturated by either beneficial or deleterious mutations. Assuming all mutations have the same magnitude selective effect, we calculate the fraction of beneficial mutations necessary to maintain the dynamic balance. This may explain the unexpected maintenance of asexual genomes, as in mitochondria, in the presence of selection. This will affect in the statistics of genetic diversity in these populations.

Lecture archiving on a larger scale at the University of Michigan and CERN

NASA Astrophysics Data System (ADS)

Herr, Jeremy; Lougheed, Robert; Neal, Homer A.

2010-04-01

The ATLAS Collaboratory Project at the University of Michigan has been a leader in the area of collaborative tools since 1999. Its activities include the development of standards, software and hardware tools for lecture archiving, and making recommendations for videoconferencing and remote teaching facilities. Starting in 2006 our group became involved in classroom recordings, and in early 2008 we spawned CARMA, a University-wide recording service. This service uses a new portable recording system that we developed. Capture, archiving and dissemination of rich multimedia content from lectures, tutorials and classes are increasingly widespread activities among universities and research institutes. A growing array of related commercial and open source technologies is becoming available, with several new products introduced in the last couple years. As the result of a new close partnership between U-M and CERN IT, a market survey of these products was conducted and a summary of the results are presented here. It is informing an ambitious effort in 2009 to equip many CERN rooms with automated lecture archiving systems, on a much larger scale than before. This new technology is being integrated with CERN's existing webcast, CDS, and Indico applications.

New directions in the CernVM file system

NASA Astrophysics Data System (ADS)

Blomer, Jakob; Buncic, Predrag; Ganis, Gerardo; Hardi, Nikola; Meusel, Rene; Popescu, Radu

2017-10-01

The CernVM File System today is commonly used to host and distribute application software stacks. In addition to this core task, recent developments expand the scope of the file system into two new areas. Firstly, CernVM-FS emerges as a good match for container engines to distribute the container image contents. Compared to native container image distribution (e.g. through the “Docker registry”), CernVM-FS massively reduces the network traffic for image distribution. This has been shown, for instance, by a prototype integration of CernVM-FS into Mesos developed by Mesosphere, Inc. We present a path for a smooth integration of CernVM-FS and Docker. Secondly, CernVM-FS recently raised new interest as an option for the distribution of experiment conditions data. Here, the focus is on improved versioning capabilities of CernVM-FS that allows to link the conditions data of a run period to the state of a CernVM-FS repository. Lastly, CernVM-FS has been extended to provide a name space for physics data for the LIGO and CMS collaborations. Searching through a data namespace is often done by a central, experiment specific database service. A name space on CernVM-FS can particularly benefit from an existing, scalable infrastructure and from the POSIX file system interface.

EFQPSK Versus CERN: A Comparative Study

NASA Technical Reports Server (NTRS)

Borah, Deva K.; Horan, Stephen

2001-01-01

This report presents a comparative study on Enhanced Feher's Quadrature Phase Shift Keying (EFQPSK) and Constrained Envelope Root Nyquist (CERN) techniques. These two techniques have been developed in recent times to provide high spectral and power efficiencies under nonlinear amplifier environment. The purpose of this study is to gain insights into these techniques and to help system planners and designers with an appropriate set of guidelines for using these techniques. The comparative study presented in this report relies on effective simulation models and procedures. Therefore, a significant part of this report is devoted to understanding the mathematical and simulation models of the techniques and their set-up procedures. In particular, mathematical models of EFQPSK and CERN, effects of the sampling rate in discrete time signal representation, and modeling of nonlinear amplifiers and predistorters have been considered in detail. The results of this study show that both EFQPSK and CERN signals provide spectrally efficient communications compared to filtered conventional linear modulation techniques when a nonlinear power amplifier is used. However, there are important differences. The spectral efficiency of CERN signals, with a small amount of input backoff, is significantly better than that of EFQPSK signals if the nonlinear amplifier is an ideal clipper. However, to achieve such spectral efficiencies with a practical nonlinear amplifier, CERN processing requires a predistorter which effectively translates the amplifier's characteristics close to those of an ideal clipper. Thus, the spectral performance of CERN signals strongly depends on the predistorter. EFQPSK signals, on the other hand, do not need such predistorters since their spectra are almost unaffected by the nonlinear amplifier, Ibis report discusses several receiver structures for EFQPSK signals. It is observed that optimal receiver structures can be realized for both coded and uncoded EFQPSK

Optical fibres in the radiation environment of CERN

NASA Astrophysics Data System (ADS)

Guillermain, E.

2017-11-01

CERN, the European Organization for Nuclear Research (in Geneva, Switzerland), is home to a complex scientific instrument: the 27-kilometre Large Hadron Collider (LHC) collides beams of high-energy particles at close to the speed of light. Optical fibres are widely used at CERN, both in surface areas (e.g. for inter-building IT networks) and in the accelerator complex underground (e.g. for cryogenics, vacuum, safety systems). Optical fibres in the accelerator are exposed to mixed radiation fields (mainly composed of protons, pions, neutrons and other hadrons, gamma rays and electrons), with dose rates depending on the particular installation zone, and with radiation levels often significantly higher than those encountered in space. In the LHC and its injector chain radiation levels range from relatively low annual doses of a few Gy up to hundreds of kGy. Optical fibres suffer from Radiation Induced Attenuation (RIA, expressed in dB per unit length) that affect light transmission and which depends on the irradiation conditions (e.g. dose rate, total dose, temperature). In the CERN accelerator complex, the failure of an optical link can affect the proper functionality of control or monitoring systems and induce the interruption of the accelerator operation. The qualification of optical fibres for installation in critical radiation areas is therefore crucial. Thus, all optical fibre types installed in radiation areas at CERN are subject to laboratory irradiation tests, in order to evaluate their RIA at different total dose and dose rates. This allows the selection of the appropriate optical fibre type (conventional or radiation resistant) compliant with the requirements of each installation. Irradiation tests are performed in collaboration with Fraunhofer INT (irradiation facilities and expert team in Euskirchen, Germany). Conventional off-the-shelf optical fibres can be installed for optical links exposed to low radiation levels (i.e. annual dose typically below few

The SHiP project at CERN

NASA Astrophysics Data System (ADS)

De Lellis, G.; SHiP Collaboration

2016-07-01

The discovery of the Higgs boson has fully confirmed the Standard Model of particles and fields. Nevertheless, there are still fundamental phenomena, like the existence of dark matter and the baryon asymmetry, which deserve an explanation that could come from the discovery of new particles. Searches for new physics with accelerators are performed at the LHC, looking for high massive particles coupled to matter with ordinary strength. A new experimental facility at CERN meant to search for very weakly coupled particles in the few GeV mass domain has been recently proposed. The existence of such particles, foreseen in different theoretical models beyond the Standard Model, is largely unexplored. A beam dump facility using 400 GeV protons is a copious factory of charmed hadrons and could be used to probe the existence of such particles. The beam dump is also a copious source of neutrinos and in particular it is an ideal source of tau neutrinos, the less known particle in the Standard Model. Indeed, tau anti-neutrinos have not been directly observed so far. We report the physics potential of such an experiment. Resistive Plate Chambers could play a role in the SHiP detector.

Commissioning results of CERN HIE-ISOLDE and INFN ALPI cryogenic control systems

NASA Astrophysics Data System (ADS)

Inglese, V.; Pezzetti, M.; Calore, A.; Modanese, P.; Pengo, R.

2017-02-01

The cryogenic systems of both accelerators, namely HIE ISOLDE (High Intensity and Energy Isotope Separator On Line DEvice) at CERN and ALPI (Acceleratore Lineare Per Ioni) at LNL, have been refurbished. HIE ISOLDE is a major upgrade of the existing ISOLDE facilities, which required the construction of a superconducting linear accelerator consisting of six cryomodules, each containing five superconductive RF cavities and superconducting solenoids. The ALPI linear accelerator, similar to HIE ISOLDE, is located at Legnaro National Laboratories (LNL) and became operational in the early 90’s. It is composed of 74 superconducting RF cavities, assembled inside 22 cryostats. The new control systems are equipped with PLC, developed on the CERN UNICOS framework, which include Schneider and Siemens PLCs and various fieldbuses (Profibus DP and PA, WorldFIP). The control systems were developed in synergy between CERN and LNL in order to build, effectively and with an optimized use of resources, control systems allowing to enhance ease of operation, maintainability, and long-term availability. This paper describes (i) the cryogenic systems, with special focus on the design of the control systems hardware and software, (ii) the strategy adopted in order to achieve a synergic approach, and (iii) the commissioning results after the cool-down to 4.5 K of the cryomodules.

Vidyo@CERN: A Service Update

NASA Astrophysics Data System (ADS)

Fernandes, J.; Baron, T.

2015-12-01

We will present an overview of the current real-time video service offering for the LHC, in particular the operation of the CERN Vidyo service will be described in terms of consolidated performance and scale: The service is an increasingly critical part of the daily activity of the LHC collaborations, topping recently more than 50 million minutes of communication in one year, with peaks of up to 852 simultaneous connections. We will elaborate on the improvement of some front-end key features such as the integration with CERN Indico, or the enhancements of the Unified Client and also on new ones, released or in the pipeline, such as a new WebRTC client and CERN SSO/Federated SSO integration. An overview of future infrastructure improvements, such as virtualization techniques of Vidyo routers and geo-location mechanisms for load-balancing and optimum user distribution across the service infrastructure will also be discussed. The work done by CERN to improve the monitoring of its Vidyo network will also be presented and demoed. As a last point, we will touch the roadmap and strategy established by CERN and Vidyo with a clear objective of optimizing the service both on the end client and backend infrastructure to make it truly universal, to serve Global Science. To achieve those actions, the introduction of the multitenant concept to serve different communities is needed. This is one of the consequences of CERN's decision to offer the Vidyo service currently operated for the LHC, to other Sciences, Institutions and Virtual Organizations beyond HEP that might express interest for it.

Techniques for hazard analysis and their use at CERN.

PubMed

Nuttall, C; Schönbacher, H

2001-01-01

CERN, The European Organisation for Nuclear Research is situated near Geneva and has its accelerators and experimental facilities astride the Swiss and French frontiers attracting physicists from all over the world to this unique laboratory. The main accelerator is situated in a 27 km underground ring and the experiments take place in huge underground caverns in order to detect the fragments resulting from the collision of subatomic particles at speeds approaching that of light. These detectors contain many hundreds of tons of flammable materials, mainly plastics in cables and structural components, flammable gases in the detectors themselves, and cryogenic fluids such as helium and argon. The experiments consume high amounts of electrical power, thus the dangers involved have necessitated the use of analytical techniques to identify the hazards and quantify the risks to personnel and the infrastructure. The techniques described in the paper have been developed in the process industries where they have been to be of great value. They have been successfully applied to CERN industrial and experimental installations and, in some cases, have been instrumental in changing the philosophy of the experimentalists and their detectors.

7Be(n,α) and 7Be(n,p) cross-section measurement for the cosmological lithium problem at the n_TOF facility at CERN

NASA Astrophysics Data System (ADS)

Barbagallo, M.; Colonna, N.; Aberle, O.; Andrzejewski, J.; Audouin, L.; Bécares, V.; Bacak, M.; Balibrea, J.; Barros, S.; Bečvář, F.; Beinrucker, C.; Berthoumieux, E.; Billowes, J.; Bosnar, D.; Brugger, M.; Caamaño, M.; Calviño, F.; Calviani, M.; Cano-Ott, D.; Cardella, R.; Casanovas, A.; Castelluccio, D. M.; Cerutti, F.; Chen, Y. H.; Chiaveri, E.; Cortés, G.; Cortés-Giraldo, M. A.; Cosentino, L.; Damone, L. A.; Diakaki, M.; Domingo-Pardo, C.; Dressler, R.; Dupont, E.; Durán, I.; Fernández-Domínguez, B.; Ferrari, A.; Ferreira, P.; Finocchiaro, P.; Furman, V.; Göbel, K.; García, A. R.; Gawlik, A.; Glodariu, T.; Gonçalves, I. F.; González, E.; Goverdovski, A.; Griesmayer, E.; Guerrero, C.; Gunsing, F.; Harada, H.; Heftrich, T.; Heinitz, S.; Heyse, J.; Jenkins, D. G.; Jericha, E.; Käppeler, F.; Kadi, Y.; Katabuchi, T.; Kavrigin, P.; Ketlerov, V.; Khryachkov, V.; Kimura, A.; Kivel, N.; Kokkoris, M.; Krtička, M.; Leal-Cidoncha, E.; Lederer, C.; Leeb, H.; Lerendegui-Marco, J.; Meo, S. Lo; Lonsdale, S. J.; Losito, R.; Macina, D.; Marganiec, J.; Martínez, T.; Massimi, C.; Mastinu, P.; Mastromarco, M.; Matteucci, F.; Maugeri, E. A.; Mendoza, E.; Mengoni, A.; Milazzo, P. M.; Mingrone, F.; Mirea, M.; Montesano, S.; Musumarra, A.; Nolte, R.; Oprea, A.; Patronis, N.; Pavlik, A.; Perkowski, J.; Porras, J. I.; Praena, J.; Quesada, J. M.; Rajeev, K.; Rauscher, T.; Reifarth, R.; Riego-Perez, A.; Rout, P. C.; Rubbia, C.; Ryan, J. A.; Sabaté-Gilarte, M.; Saxena, A.; Schillebeeckx, P.; Schmidt, S.; Schumann, D.; Sedyshev, P.; Smith, A. G.; Stamatopoulos, A.; Tagliente, G.; Tain, J. L.; Tarifeño-Saldivia, A.; Tassan-Got, L.; Tsinganis, A.; Valenta, S.; Vannini, G.; Variale, V.; Vaz, P.; Ventura, A.; Vlachoudis, V.; Vlastou, R.; Wallner, A.; Warren, S.; Weigand, M.; Weiss, C.; Wolf, C.; Woods, P. J.; Wright, T.; Žugec, P.

2017-09-01

The Cosmological Lithium Problem refers to the large discrepancy between the abundance of primordial 7Li predicted by the standard theory of Big Bang Nucleosynthesis and the value inferred from the so-called "Spite plateau" in halo stars. A possible explanation for this longstanding puzzle in Nuclear Astrophysics is related to the incorrect estimation of the destruction rate of 7Be, which is responsible for the production of 95% of primordial Lithium. While charged-particle induced reactions have mostly been ruled out, data on the 7Be(n,α) and 7Be(n,p) reactions are scarce or completely missing, so that a large uncertainty still affects the abundance of 7Li predicted by the standard theory of Big Bang Nucleosynthesis. Both reactions have been measured at the n_TOF facility at CERN, providing for the first time data in a wide neutron energy range.

Does conservation on farmland contribute to halting the biodiversity decline?

PubMed

Kleijn, David; Rundlöf, Maj; Scheper, Jeroen; Smith, Henrik G; Tscharntke, Teja

2011-09-01

Biodiversity continues to decline, despite the implementation of international conservation conventions and measures. To counteract biodiversity loss, it is pivotal to know how conservation actions affect biodiversity trends. Focussing on European farmland species, we review what is known about the impact of conservation initiatives on biodiversity. We argue that the effects of conservation are a function of conservation-induced ecological contrast, agricultural land-use intensity and landscape context. We find that, to date, only a few studies have linked local conservation effects to national biodiversity trends. It is therefore unknown how the extensive European agri-environmental budget for conservation on farmland contributes to the policy objectives to halt biodiversity decline. Based on this review, we identify new research directions addressing this important knowledge gap. Copyright © 2011 Elsevier Ltd. All rights reserved.

Simulations of beam-matter interaction experiments at the CERN HiRadMat facility and prospects of high-energy-density physics research.

PubMed

Tahir, N A; Burkart, F; Shutov, A; Schmidt, R; Wollmann, D; Piriz, A R

2014-12-01

In a recent publication [Schmidt et al., Phys. Plasmas 21, 080701 (2014)], we reported results on beam-target interaction experiments that have been carried out at the CERN HiRadMat (High Radiation to Materials) facility using extended solid copper cylindrical targets that were irradiated with a 440-GeV proton beam delivered by the Super Proton Synchrotron (SPS). On the one hand, these experiments confirmed the existence of hydrodynamic tunneling of the protons that leads to substantial increase in the range of the protons and the corresponding hadron shower in the target, a phenomenon predicted by our previous theoretical investigations [Tahir et al., Phys. Rev. ST Accel. Beams 25, 051003 (2012)]. On the other hand, these experiments demonstrated that the beam heated part of the target is severely damaged and is converted into different phases of high energy density (HED) matter, as suggested by our previous theoretical studies [Tahir et al., Phys. Rev. E 79, 046410 (2009)]. The latter confirms that the HiRadMat facility can be used to study HED physics. In the present paper, we give details of the numerical simulations carried out to understand the experimental measurements. These include the evolution of the physical parameters, for example, density, temperature, pressure, and the internal energy in the target, during and after the irradiation. This information is important in order to determine the region of the HED phase diagram that can be accessed in such experiments. These simulations have been done using the energy deposition code fluka and a two-dimensional hydrodynamic code, big2, iteratively.

Evaluation results of xTCA equipment for HEP experiments at CERN

NASA Astrophysics Data System (ADS)

Di Cosmo, M.; Bobillier, V.; Haas, S.; Joos, M.; Mico, S.; Vasey, F.; Vichoudis, P.

2013-12-01

The MicroTCA and AdvancedTCA industry standards are candidate modular electronic platforms for the upgrade of the current generation of high energy physics experiments. The PH-ESE group at CERN launched in 2011 the xTCA evaluation project with the aim of performing technical evaluations and eventually providing support for commercially available components. Different devices from different vendors have been acquired, evaluated and interoperability tests have been performed. This paper presents the test procedures and facilities that have been developed and focuses on the evaluation results including electrical, thermal and interoperability aspects.

CERN alerter—RSS based system for information broadcast to all CERN offices

NASA Astrophysics Data System (ADS)

Otto, R.

2008-07-01

Nearly every large organization uses a tool to broadcast messages and information across the internal campus (messages like alerts announcing interruption in services or just information about upcoming events). These tools typically allow administrators (operators) to send 'targeted' messages which are sent only to specific groups of users or computers, e/g only those located in a specified building or connected to a particular computing service. CERN has a long history of such tools: CERNVMS's SPM_quotMESSAGE command, Zephyr [2] and the most recent the NICE Alerter based on the NNTP protocol. The NICE Alerter used on all Windows-based computers had to be phased out as a consequence of phasing out NNTP at CERN. The new solution to broadcast information messages on the CERN campus continues to provide the service based on cross-platform technologies, hence minimizing custom developments and relying on commercial software as much as possible. The new system, called CERN Alerter, is based on RSS (Really Simple Syndication) [9] for the transport protocol and uses Microsoft SharePoint as the backend for database and posting interface. The windows-based client relies on Internet Explorer 7.0 with custom code to trigger the window pop-ups and the notifications for new events. Linux and Mac OS X clients could also rely on any RSS readers to subscribe to targeted notifications. The paper covers the architecture and implementation aspects of the new system.

CERN and high energy physics, the grand picture

ScienceCinema

Heuer, Rolf-Dieter

2018-05-24

The lecture will touch on several topics, to illustrate the role of CERN in the present and future of high-energy physics: how does CERN work? What is the role of the scientific community, of bodies like Council and SPC, and of international cooperation, in the definition of CERN's scientific programme? What are the plans for the future of the LHC and of the non-LHC physics programme? What is the role of R&D; and technology transfer at CERN?

NEWS: A trip to CERN

NASA Astrophysics Data System (ADS)

Ellison, A. D.

2000-07-01

the canteen. Over lunch we mixed with physicists of many different nationalities and backgrounds. Figure 1 Figure 1. In the afternoon we visited Microcosm, the CERN visitors centre, and the LEP control room and also the SPS. Here the students learned new applications for much of the physics of standing waves and resonance that they had been taught in the classroom. Later that night, we visited a bowling alley where momentum and collision theory were put into practice. The following morning we returned to CERN and visited the large magnet testing facility. Here again physics was brought to life. We saw superconducting magnets being assembled and tested and the students gained a real appreciation of the problems and principles involved. The afternoon was rounded off by a visit to a science museum in Geneva - well worth a visit, as some of us still use some of the apparatus on display. Friday was our last full day so we visited Chamonix in the northern Alps. In the morning, we ascended the Aiguille de Midi - by cable car. Twenty minutes and 3842 m later we emerged into 50 km h-1 winds and -10 °C temperature, not counting the -10 °C wind chill factor. A crisp packet provided an unusual demonstration of the effects of air pressure (figure 2). Figure 2 Figure 2. The views from the summit were very spectacular though a few people experienced mild altitude sickness. That afternoon the party went to the Mer de Glace. Being inside a 3 million year-old structure moving down a mountain at 3 cm per day was an interesting experience, as was a tot of whisky with 3 million year-old water. Once again the local scenery was very photogenic and the click and whirr of cameras was a constant background noise. Saturday morning saw an early start for the long drive home. Most students - and some staff - took the opportunity to catch up on their sleep. Thanks are due to many people without whom the trip would never have taken place. Anne Craige, Stuart Williams

Integrated Facilities and Infrastructure Plan.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reisz Westlund, Jennifer Jill

Our facilities and infrastructure are a key element of our capability-based science and engineering foundation. The focus of the Integrated Facilities and Infrastructure Plan is the development and implementation of a comprehensive plan to sustain the capabilities necessary to meet national research, design, and fabrication needs for Sandia National Laboratories’ (Sandia’s) comprehensive national security missions both now and into the future. A number of Sandia’s facilities have reached the end of their useful lives and many others are not suitable for today’s mission needs. Due to the continued aging and surge in utilization of Sandia’s facilities, deferred maintenance has continuedmore » to increase. As part of our planning focus, Sandia is committed to halting the growth of deferred maintenance across its sites through demolition, replacement, and dedicated funding to reduce the backlog of maintenance needs. Sandia will become more agile in adapting existing space and changing how space is utilized in response to the changing requirements. This Integrated Facilities & Infrastructure (F&I) Plan supports the Sandia Strategic Plan’s strategic objectives, specifically Strategic Objective 2: Strengthen our Laboratories’ foundation to maximize mission impact, and Strategic Objective 3: Advance an exceptional work environment that enables and inspires our people in service to our nation. The Integrated F&I Plan is developed through a planning process model to understand the F&I needs, analyze solution options, plan the actions and funding, and then execute projects.« less

25th Birthday Cern- Amphi

ScienceCinema

None

2017-12-09

Cérémonie du 25ème anniversaire du Cern avec 2 orateurs: le Prof.Weisskopf parle de la signification et le rôle du Cern et le Prof.Casimir(?) fait un exposé sur les rélations entre la science pure et la science appliquée et la "big science" (science légère)

CERN automatic audio-conference service

NASA Astrophysics Data System (ADS)

Sierra Moral, Rodrigo

2010-04-01

Scientists from all over the world need to collaborate with CERN on a daily basis. They must be able to communicate effectively on their joint projects at any time; as a result telephone conferences have become indispensable and widely used. Managed by 6 operators, CERN already has more than 20000 hours and 5700 audio-conferences per year. However, the traditional telephone based audio-conference system needed to be modernized in three ways. Firstly, to provide the participants with more autonomy in the organization of their conferences; secondly, to eliminate the constraints of manual intervention by operators; and thirdly, to integrate the audio-conferences into a collaborative working framework. The large number, and hence cost, of the conferences prohibited externalization and so the CERN telecommunications team drew up a specification to implement a new system. It was decided to use a new commercial collaborative audio-conference solution based on the SIP protocol. The system was tested as the first European pilot and several improvements (such as billing, security, redundancy...) were implemented based on CERN's recommendations. The new automatic conference system has been operational since the second half of 2006. It is very popular for the users and has doubled the number of conferences in the past two years.

Measurement of the 238U(n ,γ ) cross section up to 80 keV with the Total Absorption Calorimeter at the CERN n_TOF facility

NASA Astrophysics Data System (ADS)

Wright, T.; Guerrero, C.; Billowes, J.; Cano-Ott, D.; Mendoza, E.; Altstadt, S.; Andrzejewski, J.; Audouin, L.; Bécares, V.; Barbagallo, M.; Bečvář, F.; Belloni, F.; Berthoumieux, E.; Bosnar, D.; Brugger, M.; Calviño, F.; Calviani, M.; Carrapiço, C.; Cerutti, F.; Chiaveri, E.; Chin, M.; Colonna, N.; Cortés, G.; Cortés-Giraldo, M. A.; Diakaki, M.; Dietz, M.; Domingo-Pardo, C.; Durán, I.; Dzysiuk, N.; Eleftheriadis, C.; Ferrari, A.; Fraval, K.; Furman, V.; Gómez-Hornillos, M. B.; Ganesan, S.; García, A. R.; Giubrone, G.; Gonçalves, I. F.; González-Romero, E.; Goverdovski, A.; Griesmayer, E.; Gunsing, F.; Gurusamy, P.; Heftrich, T.; Hernández-Prieto, A.; Jenkins, D. G.; Jericha, E.; Käppeler, F.; Kadi, Y.; Karadimos, D.; Katabuchi, T.; Ketlerov, V.; Khryachkov, V.; Koehler, P.; Kokkoris, M.; Kroll, J.; Krtička, M.; Lampoudis, C.; Langer, C.; Leal-Cidoncha, E.; Lederer, C.; Leeb, H.; Leong, L. S.; Lerendegui-Marco, J.; Losito, R.; Manousos, A.; Marganiec, J.; Martínez, T.; Massimi, C.; Mastinu, P.; Mengoni, A.; Milazzo, P. M.; Mingrone, F.; Mirea, M.; Paradela, C.; Pavlik, A.; Perkowski, J.; Praena, J.; Quesada, J. M.; Rauscher, T.; Reifarth, R.; Riego-Perez, A.; Robles, M.; Roman, F.; Rubbia, C.; Ryan, J. A.; Sabaté-Gilarte, M.; Sarmento, R.; Saxena, A.; Schillebeeckx, P.; Schmidt, S.; Schumann, D.; Sedyshev, P.; Tagliente, G.; Tain, J. L.; Tarifeño-Saldivia, A.; Tarrío, D.; Tassan-Got, L.; Tsinganis, A.; Valenta, S.; Vannini, G.; Variale, V.; Vaz, P.; Ventura, A.; Vermeulen, M. J.; Versaci, R.; Vlachoudis, V.; Vlastou, R.; Wallner, A.; Ware, T.; Weigand, M.; Weiss, C.; Žugec, P.; n TOF Collaboration

2017-12-01

The radiative capture cross section of a highly pure (99.999%), 6.125(2) grams and 9.56(5)×10-4 atoms/barn areal density 238U sample has been measured with the Total Absorption Calorimeter (TAC) in the 185 m flight path at the CERN neutron time-of-flight facility n_TOF. This measurement is in response to the NEA High Priority Request list, which demands an accuracy in this cross section of less than 3% below 25 keV. These data have undergone careful background subtraction, with special care being given to the background originating from neutrons scattered by the 238U sample. Pileup and dead-time effects have been corrected for. The measured cross section covers an energy range between 0.2 eV and 80 keV, with an accuracy that varies with neutron energy, being better than 4% below 25 keV and reaching at most 6% at higher energies.

ASK1 Inhibition Halts Disease Progression in Preclinical Models of Pulmonary Arterial Hypertension.

PubMed

Budas, Grant R; Boehm, Mario; Kojonazarov, Baktybek; Viswanathan, Gayathri; Tian, Xia; Veeroju, Swathi; Novoyatleva, Tatyana; Grimminger, Friedrich; Hinojosa-Kirschenbaum, Ford; Ghofrani, Hossein A; Weissmann, Norbert; Seeger, Werner; Liles, John T; Schermuly, Ralph T

2018-02-01

Progression of pulmonary arterial hypertension (PAH) is associated with pathological remodeling of the pulmonary vasculature and the right ventricle (RV). Oxidative stress drives the remodeling process through activation of MAPKs (mitogen-activated protein kinases), which stimulate apoptosis, inflammation, and fibrosis. We investigated whether pharmacological inhibition of the redox-sensitive apical MAPK, ASK1 (apoptosis signal-regulating kinase 1), can halt the progression of pulmonary vascular and RV remodeling. A selective, orally available ASK1 inhibitor, GS-444217, was administered to two preclinical rat models of PAH (monocrotaline and Sugen/hypoxia), a murine model of RV pressure overload induced by pulmonary artery banding, and cellular models. Oral administration of GS-444217 dose dependently reduced pulmonary arterial pressure and reduced RV hypertrophy in PAH models. The therapeutic efficacy of GS-444217 was associated with reduced ASK1 phosphorylation, reduced muscularization of the pulmonary arteries, and reduced fibrotic gene expression in the RV. Importantly, efficacy was observed when GS-444217 was administered to animals with established disease and also directly reduced cardiac fibrosis and improved cardiac function in a model of isolated RV pressure overload. In cellular models, GS-444217 reduced phosphorylation of p38 and JNK (c-Jun N-terminal kinase) induced by adenoviral overexpression of ASK1 in rat cardiomyocytes and reduced activation/migration of primary mouse cardiac fibroblasts and human pulmonary adventitial fibroblasts derived from patients with PAH. ASK1 inhibition reduced pathological remodeling of the pulmonary vasculature and the right ventricle and halted progression of pulmonary hypertension in rodent models. These preclinical data inform the first description of a causal role of ASK1 in PAH disease pathogenesis.

Outsourcing strategy and tendering methodology for the operation and maintenance of CERN’s cryogenic facilities

NASA Astrophysics Data System (ADS)

Serio, L.; Bremer, J.; Claudet, S.; Delikaris, D.; Ferlin, G.; Ferrand, F.; Pezzetti, M.; Pirotte, O.

2017-12-01

CERN operates and maintains the world largest cryogenic infrastructure ranging from ageing but well maintained installations feeding detectors, test facilities and general services, to the state-of-the-art cryogenic system serving the flagship LHC machine complex. A study was conducted and a methodology proposed to outsource to industry the operation and maintenance of the whole cryogenic infrastructure. The cryogenic installations coupled to non LHC-detectors, test facilities and general services infrastructure have been fully outsourced for operation and maintenance on the basis of performance obligations. The contractor is responsible for the operational performance of the installations based on a yearly operation schedule provided by CERN. The maintenance of the cryogenic system serving the LHC machine and its detectors has been outsourced on the basis of tasks oriented obligations, monitored by key performance indicators. CERN operation team, with the support of the contractor operation team, remains responsible for the operational strategy and performances. We report the analysis, strategy, definition of the requirements and technical specifications as well as the achieved technical and economic performances after one year of operation.

The significance of Cern

ScienceCinema

None

2017-12-09

Le Prof. V.Weisskopf, DG du Cern de 1961 à 1965, est né à Vienne, a fait ses études à Göttingen et a une carrière académique particulièrement riche. Il a travaillé à Berlin, Copenhague et Berlin et est parti aux Etats Unis pour participer au projet Manhattan et était Prof. au MTT jusqu'à 1960. Revenu en Europe, il a été DG du Cern et lui a donné l'impulsion que l'on sait.

Learning with the ATLAS Experiment at CERN

ERIC Educational Resources Information Center

Barnett, R. M.; Johansson, K. E.; Kourkoumelis, C.; Long, L.; Pequenao, J.; Reimers, C.; Watkins, P.

2012-01-01

With the start of the LHC, the new particle collider at CERN, the ATLAS experiment is also providing high-energy particle collisions for educational purposes. Several education projects--education scenarios--have been developed and tested on students and teachers in several European countries within the Learning with ATLAS@CERN project. These…

Parasite transmission among relatives halts Red Queen dynamics.

PubMed

Greenspoon, Philip B; Mideo, Nicole

2017-03-01

The theory that coevolving hosts and parasites create a fluctuating selective environment for one another (i.e., produce Red Queen dynamics) has deep roots in evolutionary biology; yet empirical evidence for Red Queen dynamics remains scarce. Fluctuating coevolutionary dynamics underpin the Red Queen hypothesis for the evolution of sex, as well as hypotheses explaining the persistence of genetic variation under sexual selection, local parasite adaptation, the evolution of mutation rate, and the evolution of nonrandom mating. Coevolutionary models that exhibit Red Queen dynamics typically assume that hosts and parasites encounter one another randomly. However, if related individuals aggregate into family groups or are clustered spatially, related hosts will be more likely to encounter parasites transmitted by genetically similar individuals. Using a model that incorporates familial parasite transmission, we show that a slight degree of familial parasite transmission is sufficient to halt coevolutionary fluctuations. Our results predict that evidence for Red Queen dynamics, and its evolutionary consequences, are most likely to be found in biological systems in which hosts and parasites mix mainly at random, and are less likely to be found in systems with familial aggregation. This presents a challenge to the Red Queen hypothesis and other hypotheses that depend on coevolutionary cycling. © 2016 The Author(s). Evolution © 2016 The Society for the Study of Evolution.

Update on CERN Search based on SharePoint 2013

NASA Astrophysics Data System (ADS)

Alvarez, E.; Fernandez, S.; Lossent, A.; Posada, I.; Silva, B.; Wagner, A.

2017-10-01

CERN’s enterprise Search solution “CERN Search” provides a central search solution for users and CERN service providers. A total of about 20 million public and protected documents from a wide range of document collections is indexed, including Indico, TWiki, Drupal, SharePoint, JACOW, E-group archives, EDMS, and CERN Web pages. In spring 2015, CERN Search was migrated to a new infrastructure based on SharePoint 2013. In the context of this upgrade, the document pre-processing and indexing process was redesigned and generalised. The new data feeding framework allows to profit from new functionality and it facilitates the long term maintenance of the system.

CERN Collider, France-Switzerland

NASA Image and Video Library

2013-08-23

This image, acquired by NASA Terra spacecraft, is of the CERN Large Hadron Collider, the world largest and highest-energy particle accelerator laying beneath the French-Swiss border northwest of Geneva yellow circle.

Sirolimus therapy to halt the progression of ADPKD.

PubMed

Perico, Norberto; Antiga, Luca; Caroli, Anna; Ruggenenti, Piero; Fasolini, Giorgio; Cafaro, Mariateresa; Ondei, Patrizia; Rubis, Nadia; Diadei, Olimpia; Gherardi, Giulia; Prandini, Silvia; Panozo, Andrea; Bravo, Rodolfo Flores; Carminati, Sergio; De Leon, Felipe Rodriguez; Gaspari, Flavio; Cortinovis, Monica; Motterlini, Nicola; Ene-Iordache, Bogdan; Remuzzi, Andrea; Remuzzi, Giuseppe

2010-06-01

Activation of mammalian target of rapamycin (mTOR) pathways may contribute to uncontrolled cell proliferation and secondary cyst growth in patients with autosomal dominant polycystic kidney disease (ADPKD). To assess the effects of mTOR inhibition on disease progression, we performed a randomized, crossover study (The SIRENA Study) comparing a 6-month treatment with sirolimus or conventional therapy alone on the growth of kidney volume and its compartments in 21 patients with ADPKD and GFR>or=40 ml/min per 1.73 m2. In 10 of the 15 patients who completed the study, aphthous stomatitis complicated sirolimus treatment but was effectively controlled by topical therapy. Compared with pretreatment, posttreatment mean total kidney volume increased less on sirolimus (46+/-81 ml; P=0.047) than on conventional therapy (70+/-72 ml; P=0.002), but we did not detect a difference between the two treatments (P=0.45). Cyst volume was stable on sirolimus and increased by 55+/-75 ml (P=0.013) on conventional therapy, whereas parenchymal volume increased by 26+/-30 ml (P=0.005) on sirolimus and was stable on conventional therapy. Percentage changes in cyst and parenchyma volumes were significantly different between the two treatment periods. Sirolimus had no appreciable effects on intermediate volume and GFR. Albuminuria and proteinuria marginally but significantly increased during sirolimus treatment. In summary, sirolimus halted cyst growth and increased parenchymal volume in patients with ADPKD. Whether these effects translate into improved long-term outcomes requires further investigation.

CERN goes iconic

NASA Astrophysics Data System (ADS)

2017-06-01

There are more than 1800 emoji that can be sent and received in text messages and e-mails. Now, the CERN particle-physics lab near Geneva has got in on the act and released its own collection of 35 images that can be used by anyone with an Apple device.

Wi-Fi Service enhancement at CERN

NASA Astrophysics Data System (ADS)

Ducret, V.; Sosnowski, A.; Gonzalez Caballero, B.; Barrand, Q.

2017-10-01

Since the early 2000’s, the number of mobile devices connected to CERN’s internal network has increased from just a handful to well over 10,000. Wireless access is no longer simply “nice to have” or just for conference and meeting rooms; support for mobility is expected by most, if not all, of the CERN community. In this context, a full renewal of the CERN Wi-Fi network has been launched to deliver a state-of-the-art campus-wide Wi-Fi Infrastructure. We aim to deliver, in more than 200 office buildings with a surface area of over 400,000m2 and including many high-priority and high-occupation zones, an end-user experience comparable, for most applications, to a wired connection and with seamless mobility support. We describe here the studies and tests performed at CERN to ensure the solution we are deploying can meet these goals as well as delivering a single, simple, flexible and open management platform.

Review of CERN Data Centre Infrastructure

NASA Astrophysics Data System (ADS)

Andrade, P.; Bell, T.; van Eldik, J.; McCance, G.; Panzer-Steindel, B.; Coelho dos Santos, M.; Traylen and, S.; Schwickerath, U.

2012-12-01

The CERN Data Centre is reviewing strategies for optimizing the use of the existing infrastructure and expanding to a new data centre by studying how other large sites are being operated. Over the past six months, CERN has been investigating modern and widely-used tools and procedures used for virtualisation, clouds and fabric management in order to reduce operational effort, increase agility and support unattended remote data centres. This paper gives the details on the project's motivations, current status and areas for future investigation.

Big Bang Day: The Making of CERN (Episode 1)

ScienceCinema

None

2017-12-09

A two-part history of the CERN project. Quentin Cooper explores the fifty-year history of CERN, the European particle physics laboratory in Switzerland. The institution was created to bring scientists together after WW2 .......

Big Bang Day: The Making of CERN (Episode 1)

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2009-10-06

A two-part history of the CERN project. Quentin Cooper explores the fifty-year history of CERN, the European particle physics laboratory in Switzerland. The institution was created to bring scientists together after WW2 .......

Objectifying when to halt a boxing match: a video analysis of fatalities.

PubMed

Miele, Vincent J; Bailes, Julian E

2007-02-01

Although numerous prestigious medical organizations have called for its abolishment, participation in the sport of boxing has reached an all-time high among both men and women, and its elimination is unlikely in the near future. Physicians should strive to increase boxing safety by improving the rules of competition, which have evolved minimally over the past two centuries. Currently, subjective criteria are used to determine whether or not a contest should be halted. Developing a standardized, objective method of determining when a contest should be halted would be a significant paradigm shift and could increase the safety of the sport's participants. This study analyzed the number and types of punches landed in a typical professional match, in bouts considered to be competitive and in those that ended in fatalities, to determine whether or not this would be a practical method of differentiating between these groups. Three groups of professional boxing matches were defined at the beginning of the study: 1) a "fatal" group, consisting of bouts that resulted in the death of a participant; 2) a "classic" group that represented competitive matches; and 3) a "control" group of 4000 professional boxing matches representing the average bout. A computer program known as Punchstat (Compubox, Inc., Manorville, NY) was used in the objective analysis of these matches via videotape playback. Several statistically significant differences were discovered between matches that resulted in fatalities and the control group. These include the number of punches landed per round, the number of power punches landed per round, and the number of power punches thrown per round by losing boxers. However, when the fatal bouts were compared with the most competitive bouts, these differences were no longer evident. Based on the data analyzed between the control and fatal-bout groups, a computerized method of counting landed blows at ringside could provide sufficient data to stop matches that

Status and Roadmap of CernVM

NASA Astrophysics Data System (ADS)

Berzano, D.; Blomer, J.; Buncic, P.; Charalampidis, I.; Ganis, G.; Meusel, R.

2015-12-01

Cloud resources nowadays contribute an essential share of resources for computing in high-energy physics. Such resources can be either provided by private or public IaaS clouds (e.g. OpenStack, Amazon EC2, Google Compute Engine) or by volunteers computers (e.g. LHC@Home 2.0). In any case, experiments need to prepare a virtual machine image that provides the execution environment for the physics application at hand. The CernVM virtual machine since version 3 is a minimal and versatile virtual machine image capable of booting different operating systems. The virtual machine image is less than 20 megabyte in size. The actual operating system is delivered on demand by the CernVM File System. CernVM 3 has matured from a prototype to a production environment. It is used, for instance, to run LHC applications in the cloud, to tune event generators using a network of volunteer computers, and as a container for the historic Scientific Linux 5 and Scientific Linux 4 based software environments in the course of long-term data preservation efforts of the ALICE, CMS, and ALEPH experiments. We present experience and lessons learned from the use of CernVM at scale. We also provide an outlook on the upcoming developments. These developments include adding support for Scientific Linux 7, the use of container virtualization, such as provided by Docker, and the streamlining of virtual machine contextualization towards the cloud-init industry standard.

Sexual Selection Halts the Relaxation of Protamine 2 among Rodents

PubMed Central

Lüke, Lena; Vicens, Alberto; Serra, Francois; Luque-Larena, Juan Jose; Dopazo, Hernán; Roldan, Eduardo R. S.; Gomendio, Montserrat

2011-01-01

Sexual selection has been proposed as the driving force promoting the rapid evolutionary changes observed in some reproductive genes including protamines. We test this hypothesis in a group of rodents which show marked differences in the intensity of sexual selection. Levels of sperm competition were not associated with the evolutionary rates of protamine 1 but, contrary to expectations, were negatively related to the evolutionary rate of cleaved- and mature-protamine 2. Since both domains were found to be under relaxation, our findings reveal an unforeseen role of sexual selection: to halt the degree of degeneration that proteins within families may experience due to functional redundancy. The degree of relaxation of protamine 2 in this group of rodents is such that in some species it has become dysfunctional and it is not expressed in mature spermatozoa. In contrast, protamine 1 is functionally conserved but shows directed positive selection on specific sites which are functionally relevant such as DNA-anchoring domains and phosphorylation sites. We conclude that in rodents protamine 2 is under relaxation and that sexual selection removes deleterious mutations among species with high levels of sperm competition to maintain the protein functional and the spermatozoa competitive. PMID:22216223

Wolfgang Kummer at CERN

NASA Astrophysics Data System (ADS)

Schopper, Herwig

Wolfgang Kummer was not only a great theorist but also a man with a noble spirit and extensive education, based on a fascinating long-term Austrian cultural tradition. As an experimentalist I am not sufficiently knowledgeable to evaluate his contributions to theoretical physics - this will certainly be done by more competent scientists. Nevertheless I admired him for not only being attached to fundamental and abstract problems like quantum field theory, quantum gravity or black holes, but for his interest in down to earth questions like electron-proton scattering or the toponium mass. I got to know Wolfgang Kummer very well and appreciate his human qualities during his long attachment to CERN, in particular when he served as president of the CERN Council, the highest decision taking authority of this international research centre, from 1985 to 1987 falling into my term as Director-General…

CERN experience and strategy for the maintenance of cryogenic plants and distribution systems

NASA Astrophysics Data System (ADS)

Serio, L.; Bremer, J.; Claudet, S.; Delikaris, D.; Ferlin, G.; Pezzetti, M.; Pirotte, O.; Tavian, L.; Wagner, U.

2015-12-01

CERN operates and maintains the world largest cryogenic infrastructure ranging from ageing installations feeding detectors, test facilities and general services, to the state-of-the-art cryogenic system serving the flagship LHC machine complex. After several years of exploitation of a wide range of cryogenic installations and in particular following the last two years major shutdown to maintain and consolidate the LHC machine, we have analysed and reviewed the maintenance activities to implement an efficient and reliable exploitation of the installations. We report the results, statistics and lessons learned on the maintenance activities performed and in particular the required consolidations and major overhauling, the organization, management and methodologies implemented.

First experience with the new .cern Top Level Domain

NASA Astrophysics Data System (ADS)

Alvarez, E.; Malo de Molina, M.; Salwerowicz, M.; Silva De Sousa, B.; Smith, T.; Wagner, A.

2017-10-01

In October 2015, CERN’s core website has been moved to a new address, http://home.cern, marking the launch of the brand new top-level domain .cern. In combination with a formal governance and registration policy, the IT infrastructure needed to be extended to accommodate the hosting of Web sites in this new top level domain. We will present the technical implementation in the framework of the CERN Web Services that allows to provide virtual hosting, a reverse proxy solution and that also includes the provisioning of SSL server certificates for secure communications.

Dissemination of CERN's Technology Transfer: Added Value from Regional Transfer Agents

ERIC Educational Resources Information Center

Hofer, Franz

2005-01-01

Technologies developed at CERN, the European Organization for Nuclear Research, are disseminated via a network of external technology transfer officers. Each of CERN's 20 member states has appointed at least one technology transfer officer to help establish links with CERN. This network has been in place since 2001 and early experiences indicate…

Measurement and simulation of lineal energy distribution at the CERN high energy facility with a tissue equivalent proportional counter.

PubMed

Rollet, S; Autischer, M; Beck, P; Latocha, M

2007-01-01

The response of a tissue equivalent proportional counter (TEPC) in a mixed radiation field with a neutron energy distribution similar to the radiation field at commercial flight altitudes has been studied. The measurements have been done at the CERN-EU High-Energy Reference Field (CERF) facility where a well-characterised radiation field is available for intercomparison. The TEPC instrument used by the ARC Seibersdorf Research is filled with pure propane gas at low pressure and can be used to determine the lineal energy distribution of the energy deposition in a mass of gas equivalent to a 2 microm diameter volume of unit density tissue, of similar size to the nuclei of biological cells. The linearity of the detector response was checked both in term of dose and dose rate. The effect of dead-time has been corrected. The influence of the detector exposure location and orientation in the radiation field on the dose distribution was also studied as a function of the total dose. The microdosimetric distribution of the absorbed dose as a function of the lineal energy has been obtained and compared with the same distribution simulated with the FLUKA Monte Carlo transport code. The dose equivalent was calculated by folding this distribution with the quality factor as a function of linear energy transfer. The comparison between the measured and simulated distributions show that they are in good agreement. As a result of this study the detector is well characterised, thanks also to the numerical simulations the instrument response is well understood, and it's currently being used onboard the aircrafts to evaluate the dose to aircraft crew caused by cosmic radiation.

Sirolimus Therapy to Halt the Progression of ADPKD

PubMed Central

Perico, Norberto; Antiga, Luca; Caroli, Anna; Ruggenenti, Piero; Fasolini, Giorgio; Cafaro, Mariateresa; Ondei, Patrizia; Rubis, Nadia; Diadei, Olimpia; Gherardi, Giulia; Prandini, Silvia; Panozo, Andrea; Bravo, Rodolfo Flores; Carminati, Sergio; De Leon, Felipe Rodriguez; Gaspari, Flavio; Cortinovis, Monica; Motterlini, Nicola; Ene-Iordache, Bogdan; Remuzzi, Andrea

2010-01-01

Activation of mammalian target of rapamycin (mTOR) pathways may contribute to uncontrolled cell proliferation and secondary cyst growth in patients with autosomal dominant polycystic kidney disease (ADPKD). To assess the effects of mTOR inhibition on disease progression, we performed a randomized, crossover study (The SIRENA Study) comparing a 6-month treatment with sirolimus or conventional therapy alone on the growth of kidney volume and its compartments in 21 patients with ADPKD and GFR ≥40 ml/min per 1.73 m2. In 10 of the 15 patients who completed the study, aphthous stomatitis complicated sirolimus treatment but was effectively controlled by topical therapy. Compared with pretreatment, posttreatment mean total kidney volume increased less on sirolimus (46 ± 81 ml; P = 0.047) than on conventional therapy (70 ± 72 ml; P = 0.002), but we did not detect a difference between the two treatments (P = 0.45). Cyst volume was stable on sirolimus and increased by 55 ± 75 ml (P = 0.013) on conventional therapy, whereas parenchymal volume increased by 26 ± 30 ml (P = 0.005) on sirolimus and was stable on conventional therapy. Percentage changes in cyst and parenchyma volumes were significantly different between the two treatment periods. Sirolimus had no appreciable effects on intermediate volume and GFR. Albuminuria and proteinuria marginally but significantly increased during sirolimus treatment. In summary, sirolimus halted cyst growth and increased parenchymal volume in patients with ADPKD. Whether these effects translate into improved long-term outcomes requires further investigation. PMID:20466742

Offering Global Collaboration Services beyond CERN and HEP

NASA Astrophysics Data System (ADS)

Fernandes, J.; Ferreira, P.; Baron, T.

2015-12-01

The CERN IT department has built over the years a performant and integrated ecosystem of collaboration tools, from videoconference and webcast services to event management software. These services have been designed and evolved in very close collaboration with the various communities surrounding the laboratory and have been massively adopted by CERN users. To cope with this very heavy usage, global infrastructures have been deployed which take full advantage of CERN's international and global nature. If these services and tools are instrumental in enabling the worldwide collaboration which generates major HEP breakthroughs, they would certainly also benefit other sectors of science in which globalization has already taken place. Some of these services are driven by commercial software (Vidyo or Wowza for example), some others have been developed internally and have already been made available to the world as Open Source Software in line with CERN's spirit and mission. Indico for example is now installed in 100+ institutes worldwide. But providing the software is often not enough and institutes, collaborations and project teams do not always possess the expertise, or human or material resources that are needed to set up and maintain such services. Regional and national institutions have to answer needs, which are growingly global and often contradict their operational capabilities or organizational mandate and so are looking at existing worldwide service offers such as CERN's. We believe that the accumulated experience obtained through the operation of a large scale worldwide collaboration service combined with CERN's global network and its recently- deployed Agile Infrastructure would allow the Organization to set up and operate collaborative services, such as Indico and Vidyo, at a much larger scale and on behalf of worldwide research and education institutions and thus answer these pressing demands while optimizing resources at a global level. Such services would

PREFACE: Lectures from the CERN Winter School on Strings, Supergravity and Gauge Theories, CERN, 9-13 February 2009 Lectures from the CERN Winter School on Strings, Supergravity and Gauge Theories, CERN, 9-13 February 2009

NASA Astrophysics Data System (ADS)

Uranga, A. M.

2009-11-01

This special section is devoted to the proceedings of the conference `Winter School on Strings, Supergravity and Gauge Theories', which took place at CERN, the European Centre for Nuclear Research, in Geneva, Switzerland 9-13 February 2009. This event is part of a yearly series of scientific schools, which represents a well established tradition. Previous events have been held at SISSA, in Trieste, Italy, in February 2005 and at CERN in January 2006, January 2007 and January 2008, and were funded by the European Mobility Research and Training Network `Constituents, Fundamental Forces and Symmetries of the Universe'. The next event will take place again at CERN, in January 2010. The school was primarily meant for young doctoral students and postdoctoral researchers working in the area of string theory. It consisted of several general lectures of four hours each, whose notes are published in this special section, and six working group discussion sessions, focused on specific topics of the network research program. It was well attended by over 200 participants. The topics of the lectures were chosen to provide an introduction to some of the areas of recent progress, and to the open problems, in string theory. One of the most active areas in string theory in recent years has been the AdS/CFT or gauge/gravity correspondence, which proposes the complete equivalence of string theory on (asymptotically) anti de Sitter spacetimes with certain quantum (gauge) field theories. The duality has recently been applied to understanding the hydrodynamical properties of a hot plasma in gauge theories (like the quark-gluon plasma created in heavy ion collisions at the RHIC experiment at Brookhaven, and soon at the LHC at CERN) in terms of a dual gravitational AdS theory in the presence of a black hole. These developments were reviewed in the lecture notes by M Rangamani. In addition, the AdS/CFT duality has been proposed as a tool to study interesting physical properties in other

The SHiP experiment at CERN SPS

NASA Astrophysics Data System (ADS)

Di Crescenzo, A.; SHiP Collaboration

2016-01-01

SHiP is a new general purpose fixed target facility, whose Technical Proposal has been recently submitted to the CERN SPS Committee. In its initial phase, the 400GeV proton beam extracted from the SPS will be dumped on a heavy target with the aim of integrating 2×1020 pot in 5years. A dedicated detector located downstream of the target, based on a long vacuum tank followed by a spectrometer and particle identification detectors, will allow probing a variety of models with light long-lived exotic particles and masses below a few GeV/c2. The beam dump is also an ideal source of tau neutrinos, the less known particle in the Standard Model. Another dedicated detector, based on the Emulsion Cloud Chamber technology already used in the OPERA experiment, will allow to perform for the first time measurements of the tau neutrino deep inelastic scattering cross section. Tau neutrinos will be distinguished from tau anti-neutrinos, thus providing the first observation of the tau anti-neutrino.

The SHiP experiment at CERN

NASA Astrophysics Data System (ADS)

De Lellis, G.; SHiP Collaboration

2017-04-01

The discovery of the Higgs boson has fully confirmed the Standard Model of particles and fields. Nevertheless, there are still fundamental phenomena, like the existence of dark matter and the baryon asymmetry of the Universe, which deserve an explanation that could come from the discovery of new particles. Searches for new physics with accelerators are performed at the LHC, looking for high massive particles coupled to matter with ordinary strength. A new experiment at CERN meant to search for very weakly coupled particles in the few GeV mass domain has been recently proposed. The existence of such particles, foreseen in different theoretical models beyond the Standard Model, is largely unexplored. A beam dump facility using high intensity 400 GeV protons is a copious source of such unknown particles in the GeV mass range. The beam dump is also a copious source of neutrinos and in particular it is an ideal source of tau neutrinos, the less known particle in the Standard Model. Indeed, tau anti-neutrinos have not been directly observed so far. We report the physics potential of such an experiment.

The SHiP experiment at CERN

NASA Astrophysics Data System (ADS)

Bonivento, Walter M.

2017-07-01

The discovery of the Higgs boson has fully confirmed the Standard Model of particles and fields. Nevertheless, there are still fundamental phenomena, like the existence of dark matter and the baryon asymmetry of the Universe, deserving an explanation that could come from the discovery of new particles. Searches for new physics with accelerators are performed at the LHC, looking for high massive particles coupled to matter with ordinary strength. A new experiment at CERN meant to search for very weakly coupled particles in the few GeV mass domain has been recently proposed. The existence of such particles, foreseen in different theoretical models beyond the Standard Model, is largely unexplored. A beam dump facility using high intensity 400 GeV protons is a copious source of such unknown particles in the GeV mass range. The beam dump is also a copious source of neutrinos and in particular it is an ideal source of tau neutrinos, the less known particle in the Standard Model. The neutrino detector can also search for dark matter through its scattering off the electrons. We report the physics potential of the SHiP experiment.

Advance, Retreat, and Halt of Abrupt Gravel-Sand Transitions in Alluvial Rivers

NASA Astrophysics Data System (ADS)

Blom, Astrid; Chavarrías, Víctor; Ferguson, Robert I.; Viparelli, Enrica

2017-10-01

Downstream fining of bed sediment in alluvial rivers is usually gradual, but often an abrupt decrease in characteristic grain size occurs from about 10 to 1 mm, i.e., a gravel-sand transition (GST) or gravel front. Here we present an analytical model of GST migration that explicitly accounts for gravel and sand transport and deposition in the gravel reach, sea level change, subsidence, and delta progradation. The model shows that even a limited gravel supply to a sand bed reach induces progradation of a gravel wedge and predicts the circumstances required for the gravel front to advance, retreat, and halt. Predicted modern GST migration rates agree well with measured data at Allt Dubhaig and the Fraser River, and the model qualitatively captures the behavior of other documented gravel fronts. The analysis shows that sea level change, subsidence, and delta progradation have a significant impact on the GST position in lowland rivers.

History of Cern

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2007-12-20

Cérémonie à l'occasion de l'apparition du premier volume du livre sur l'histoire du Cern, avec plusieurs personnes présentes qui jouaient un rôle important dans cette organisation européenne couronnée de succès grâce à l'esprit des membres fondateurs qui est et restera essentiel

New vertical cryostat for the high field superconducting magnet test station at CERN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vande Craen, A.; Atieh, S.; Bajko, M.

2014-01-29

In the framework of the R and D program for new superconducting magnets for the Large Hadron Collider accelerator upgrades, CERN is building a new vertical test station to test high field superconducting magnets of unprecedented large size. This facility will allow testing of magnets by vertical insertion in a pressurized liquid helium bath, cooled to a controlled temperature between 4.2 K and 1.9 K. The dimensions of the cryostat will allow testing magnets of up to 2.5 m in length with a maximum diameter of 1.5 m and a mass of 15 tons. To allow for a faster insertionmore » and removal of the magnets and reducing the risk of helium leaks, all cryogenics supply lines are foreseen to remain permanently connected to the cryostat. A specifically designed 100 W heat exchanger is integrated in the cryostat helium vessel for a controlled cooling of the magnet from 4.2 K down to 1.9 K in a 3 m{sup 3} helium bath. This paper describes the cryostat and its main functions, focusing on features specifically developed for this project. The status of the construction and the plans for assembly and installation at CERN are also presented.« less

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

None

2018-05-15

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network Constituents, Fundamental Forces and Symmetries of the Universe. The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva.

Patterns of Kidney Function Decline in Autosomal Dominant Polycystic Kidney Disease: A Post Hoc Analysis From the HALT-PKD Trials.

PubMed

Brosnahan, Godela M; Abebe, Kaleab Z; Moore, Charity G; Rahbari-Oskoui, Frederic F; Bae, Kyongtae T; Grantham, Jared J; Schrier, Robert W; Braun, William E; Chapman, Arlene B; Flessner, Michael F; Harris, Peter C; Hogan, Marie C; Perrone, Ronald D; Miskulin, Dana C; Steinman, Theodore I; Torres, Vicente E

2018-05-01

Previous clinical studies of autosomal dominant polycystic kidney disease (ADPKD) reported that loss of kidney function usually follows a steep and relentless course. A detailed examination of individual patterns of decline in estimated glomerular filtration rate (eGFR) has not been performed. Longitudinal post hoc analysis of data collected during the Halt Progression of Polycystic Kidney Disease (HALT-PKD) trials. 494 HALT-PKD Study A participants (younger; preserved eGFR) and 435 Study B participants (older; reduced eGFR) who had more than 3 years of follow-up and 7 or more eGFR assessments. Longitudinal eGFR assessments using the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) creatinine equation. Demographic, clinical, laboratory, and imaging features of participants. Probability of linear and nonlinear decline patterns or of stable eGFR calculated for each participant from a Bayesian model of individual eGFR trajectories. Most (62.5% in Study A and 81% in Study B) participants had a linear decline in eGFR during up to 8 years of follow-up. A proportion (22% in Study A and 13% in Study B) of progressors had a nonlinear pattern. 15.5% of participants in Study A and 6% in Study B had a prolonged (≥4.5 years) period of stable eGFRs. These individuals (Study A) had significantly smaller total kidney volumes, higher renal blood flows, lower urinary albumin excretion, and lower body mass index at baseline and study end. In Study B, participants with reduced but stable eGFRs were older than the progressors. Two-thirds of nonprogressors in both studies had PKD1 mutations, with enrichment for weak nontruncating mutations. Relatively short follow-up of a clinical trial population. Although many individuals with ADPKD have a linear decline in eGFR, prolonged intervals of stable GFRs occur in a substantial fraction. Lower body mass index was associated with more stable kidney function in early ADPKD. Copyright © 2017 National Kidney Foundation, Inc

HALT & REVERSE: Hsf1 activators lower cardiomyocyt damage; towards a novel approach to REVERSE atrial fibrillation.

PubMed

Lanters, Eva A H; van Marion, Denise M S; Kik, Charles; Steen, Herman; Bogers, Ad J J C; Allessie, Maurits A; Brundel, Bianca J J M; de Groot, Natasja M S

2015-11-05

Atrial fibrillation is a progressive arrhythmia, the exact mechanism underlying the progressive nature of recurrent AF episodes is still unknown. Recently, it was found that key players of the protein quality control system of the cardiomyocyte, i.e. Heat Shock Proteins, protect against atrial fibrillation progression by attenuating atrial electrical and structural remodeling (electropathology). HALT & REVERSE aims to investigate the correlation between electropathology, as defined by endo- or epicardial mapping, Heat Shock Protein levels and development or recurrence of atrial fibrillation following pulmonary vein isolation, or electrical cardioversion or cardiothoracic surgery. This study is a prospective observational study. Three separate study groups are defined: (1) cardiothoracic surgery, (2) pulmonary vein isolation and (3) electrical cardioversion. An intra-operative high-resolution epicardial (group 1) or endocardial (group 2) mapping procedure of the atria is performed to study atrial electropathology. Blood samples for Heat Shock Protein determination are obtained at baseline and during the follow-up period at 3 months (group 2), 6 months (groups 1 and 2) and 1 year (group 1 and 2). Tissue samples of the right and left atrial appendages in patients in group 1 are analysed for Heat Shock Protein levels and for tissue characteristics. Early post procedural atrial fibrillation is detected by continuous rhythm monitoring, whereas late post procedural atrial fibrillation is documented by either electrocardiogram or 24-h Holter registration. HALT & REVERSE aims to identify the correlation between Heat Shock Protein levels and degree of electropathology. The study outcome will contribute to novel diagnostic tools for the early recognition of clinical atrial fibrillation. Rotterdam Medical Ethical Committee MEC-2014-393, Dutch Trial Registration NTR4658.

HIGH ENERGY PHYSICS: Bulgarians Sue CERN for Leniency.

PubMed

Koenig, R

2000-10-13

In cash-strapped Bulgaria, scientists are wondering whether a ticket for a front-row seat in high-energy physics is worth the price: Membership dues in CERN, the European particle physics lab, nearly equal the country's entire budget for competitive research grants. Faced with that grim statistic and a plea for leniency from Bulgaria's government, CERN's governing council is considering slashing the country's membership dues for the next 2 years.

Hands on CERN: A Well-Used Physics Education Project

ERIC Educational Resources Information Center

Johansson, K. E.

2006-01-01

The "Hands on CERN" education project makes it possible for students and teachers to get close to the forefront of scientific research. The project confronts the students with contemporary physics at its most fundamental level with the help of particle collisions from the DELPHI particle physics experiment at CERN. It now exists in 14 languages…

History of Cern

ScienceCinema

None

2017-12-09

Cérémonie à l'occasion de l'apparition du premier volume du livre sur l'histoire du Cern, avec plusieurs personnes présentes qui jouaient un rôle important dans cette organisation européenne couronnée de succès grâce à l'esprit des membres fondateurs qui est et restera essentiel

Prospects for observation at CERN in NA62

NASA Astrophysics Data System (ADS)

Hahn, F.; NA62 Collaboration; Aglieri Rinella, G.; Aliberti, R.; Ambrosino, F.; Angelucci, B.; Antonelli, A.; Anzivino, G.; Arcidiacono, R.; Azhinenko, I.; Balev, S.; Bendotti, J.; Biagioni, A.; Biino, C.; Bizzeti, A.; Blazek, T.; Blik, A.; Bloch-Devaux, B.; Bolotov, V.; Bonaiuto, V.; Bragadireanu, M.; Britton, D.; Britvich, G.; Brook, N.; Bucci, F.; Butin, F.; Capitolo, E.; Capoccia, C.; Capussela, T.; Carassiti, V.; Cartiglia, N.; Cassese, A.; Catinaccio, A.; Cecchetti, A.; Ceccucci, A.; Cenci, P.; Cerny, V.; Cerri, C.; Chikilev, O.; Ciaranfi, R.; Collazuol, G.; Cooke, P.; Cooper, P.; Corradi, G.; Cortina Gil, E.; Costantini, F.; Cotta Ramusino, A.; Coward, D.; D'Agostini, G.; Dainton, J.; Dalpiaz, P.; Danielsson, H.; Degrange, J.; De Simone, N.; Di Filippo, D.; Di Lella, L.; Dixon, N.; Doble, N.; Duk, V.; Elsha, V.; Engelfried, J.; Enik, T.; Falaleev, V.; Fantechi, R.; Federici, L.; Fiorini, M.; Fry, J.; Fucci, A.; Fulton, L.; Gallorini, S.; Gatignon, L.; Gianoli, A.; Giudici, S.; Glonti, L.; Goncalves Martins, A.; Gonnella, F.; Goudzovski, E.; Guida, R.; Gushchin, E.; Hahn, F.; Hallgren, B.; Heath, H.; Herman, F.; Hutchcroft, D.; Iacopini, E.; Jamet, O.; Jarron, P.; Kampf, K.; Kaplon, J.; Karjavin, V.; Kekelidze, V.; Kholodenko, S.; Khoriauli, G.; Khudyakov, A.; Kiryushin, Yu; Kleinknecht, K.; Kluge, A.; Koval, M.; Kozhuharov, V.; Krivda, M.; Kudenko, Y.; Kunze, J.; Lamanna, G.; Lazzeroni, C.; Leitner, R.; Lenci, R.; Lenti, M.; Leonardi, E.; Lichard, P.; Lietava, R.; Litov, L.; Lomidze, D.; Lonardo, A.; Lurkin, N.; Madigozhin, D.; Maire, G.; Makarov, A.; Mannelli, I.; Mannocchi, G.; Mapelli, A.; Marchetto, F.; Massarotti, P.; Massri, K.; Matak, P.; Mazza, G.; Menichetti, E.; Mirra, M.; Misheva, M.; Molokanova, N.; Morant, J.; Morel, M.; Moulson, M.; Movchan, S.; Munday, D.; Napolitano, M.; Newson, F.; Norton, A.; Noy, M.; Nuessle, G.; Obraztsov, V.; Padolski, S.; Page, R.; Palladino, V.; Pardons, A.; Pedreschi, E.; Pepe, M.; Perez Gomez, F.; Perrin-Terrin, M.; Petrov, P.; Petrucci, F.; Piandani, R.; Piccini, M.; Pietreanu, D.; Pinzino, J.; Pivanti, M.; Polenkevich, I.; Popov, I.; Potrebenikov, Yu; Protopopescu, D.; Raffaelli, F.; Raggi, M.; Riedler, P.; Romano, A.; Rubin, P.; Ruggiero, G.; Russo, V.; Ryjov, V.; Salamon, A.; Salina, G.; Samsonov, V.; Santovetti, E.; Saracino, G.; Sargeni, F.; Schifano, S.; Semenov, V.; Sergi, A.; Serra, M.; Shkarovskiy, S.; Sotnikov, A.; Sougonyaev, V.; Sozzi, M.; Spadaro, T.; Spinella, F.; Staley, R.; Statera, M.; Sutcliffe, P.; Szilasi, N.; Tagnani, D.; Valdata-Nappi, M.; Valente, P.; Vasile, M.; Vassilieva, V.; Velghe, B.; Veltri, M.; Venditti, S.; Vormstein, M.; Wahl, H.; Wanke, R.; Wertelaers, P.; Winhart, A.; Winston, R.; Wrona, B.; Yushchenko, O.; Zamkovsky, M.; Zinchenko, A.

2015-07-01

The rare decays are excellent processes to probe the Standard Model and indirectly search for new physics complementary to the direct LHC searches. The NA62 experiment at CERN SPS aims to collect and analyse O(1013) kaon decays before the CERN long-shutdown 2 (in 2018). This will allow to measure the branching ratio to a level of 10% accuracy. The experimental apparatus has been commissioned during a first run in autumn 2014.

Disk storage at CERN

NASA Astrophysics Data System (ADS)

Mascetti, L.; Cano, E.; Chan, B.; Espinal, X.; Fiorot, A.; González Labrador, H.; Iven, J.; Lamanna, M.; Lo Presti, G.; Mościcki, JT; Peters, AJ; Ponce, S.; Rousseau, H.; van der Ster, D.

2015-12-01

CERN IT DSS operates the main storage resources for data taking and physics analysis mainly via three system: AFS, CASTOR and EOS. The total usable space available on disk for users is about 100 PB (with relative ratios 1:20:120). EOS actively uses the two CERN Tier0 centres (Meyrin and Wigner) with 50:50 ratio. IT DSS also provide sizeable on-demand resources for IT services most notably OpenStack and NFS-based clients: this is provided by a Ceph infrastructure (3 PB) and few proprietary servers (NetApp). We will describe our operational experience and recent changes to these systems with special emphasis to the present usages for LHC data taking, the convergence to commodity hardware (nodes with 200-TB each with optional SSD) shared across all services. We also describe our experience in coupling commodity and home-grown solution (e.g. CERNBox integration in EOS, Ceph disk pools for AFS, CASTOR and NFS) and finally the future evolution of these systems for WLCG and beyond.

Early intranasal insulin therapy halts progression of neurodegeneration: progress in Alzheimer's disease therapeutics.

PubMed

de la Monte, Suzanne M

Evaluation of Craft S, Baker LD, Montine TJ, Minoshima S, Watson GS, Claxton A, et al. Intranasal Insulin Therapy for Alzheimer Disease and Amnestic Mild Cognitive Impairment: A Pilot Clinical Trial. Arch Neurol . 2011 Sep 12. Alzheimer's disease is associated with brain insulin deficiency and insulin resistance, similar to the problems in diabetes. If insulin could be supplied to the brain in the early stages of Alzheimer's, subsequent neurodegeneration might be prevented. Administering systemic insulin to elderly non-diabetics poses unacceptable risks of inadvertant hypoglycemia. However, intranasal delivery directs the insulin into the brain, avoiding systemic side-effects. This pilot study demonstrates both efficacy and safety of using intranasal insulin to treat early Alzheimer's and mild cognitive impairment, i.e. the precursor to Alzheimer's. Significant improvements in learning, memory, and cognition occured within a few months, but without intranasal insulin, brain function continued to deteriorate in measurable degrees. Intranasal insulin therapy holds promise for halting progression of Alzheimer's disease.

CERN's approach to public outreach

NASA Astrophysics Data System (ADS)

Landua, Rolf

2016-03-01

CERN's communication goes beyond publishing scientific results. Education and outreach are equally important ways of communicating with the general public, and in particular with the young generation. Over the last decade, CERN has significantly increased its efforts to accommodate the very large interest of the general public (about 300,000 visit requests per year), by ramping up its capacity for guided tours from 25,000 to more than 100,000 visitors per year, by creating six new of state-of-the-art exhibitions on-site, by building and operating a modern physics laboratory for school teachers and students, and by showing several traveling exhibitions in about 10 countries per year. The offer for school teachers has also been expanded, to 35-40 weeks of teacher courses with more than 1000 participants from more than 50 countries per year. The talk will give an overview about these and related activities.

CERN: A European laboratory for a global project

NASA Astrophysics Data System (ADS)

Voss, Rüdiger

2015-06-01

In the most important shift of paradigm of its membership rules in 60 years, CERN in 2010 introduced a policy of “Geographical Enlargement” which for the first time opened the door for membership of non-European States in the Organization. This short article reviews briefly the history of CERN's membership rules, discusses the rationale behind the new policy, its relationship with the emerging global roadmap of particle physics, and gives a short overview of the status of the enlargement process.

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

McAllister, Liam

2018-05-14

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

None

2018-05-22

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons.Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

Sen, Ashoke

2017-12-18

Part 7.The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

None

2018-06-28

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

None

2018-05-23

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

None

2017-12-09

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

None

2018-02-09

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental InteractionS". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

McAllister, Liam

2018-05-24

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe";. The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions".This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde. Local organizers: A. Uranga, J. Walcher

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

Sen, Ashoke

2018-04-27

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network". The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher.

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2010-01-22

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series ofmore » pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher« less

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

None

2018-05-23

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe";. The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher

CERN data services for LHC computing

NASA Astrophysics Data System (ADS)

Espinal, X.; Bocchi, E.; Chan, B.; Fiorot, A.; Iven, J.; Lo Presti, G.; Lopez, J.; Gonzalez, H.; Lamanna, M.; Mascetti, L.; Moscicki, J.; Pace, A.; Peters, A.; Ponce, S.; Rousseau, H.; van der Ster, D.

2017-10-01

Dependability, resilience, adaptability and efficiency. Growing requirements require tailoring storage services and novel solutions. Unprecedented volumes of data coming from the broad number of experiments at CERN need to be quickly available in a highly scalable way for large-scale processing and data distribution while in parallel they are routed to tape for long-term archival. These activities are critical for the success of HEP experiments. Nowadays we operate at high incoming throughput (14GB/s during 2015 LHC Pb-Pb run and 11PB in July 2016) and with concurrent complex production work-loads. In parallel our systems provide the platform for the continuous user and experiment driven work-loads for large-scale data analysis, including end-user access and sharing. The storage services at CERN cover the needs of our community: EOS and CASTOR as a large-scale storage; CERNBox for end-user access and sharing; Ceph as data back-end for the CERN OpenStack infrastructure, NFS services and S3 functionality; AFS for legacy distributed-file-system services. In this paper we will summarise the experience in supporting LHC experiments and the transition of our infrastructure from static monolithic systems to flexible components providing a more coherent environment with pluggable protocols, tuneable QoS, sharing capabilities and fine grained ACLs management while continuing to guarantee dependable and robust services.

Neutrino Factory Plans at CERN

NASA Astrophysics Data System (ADS)

Riche, J. A.

2002-10-01

The considerable interest raised by the discovery of neutrino oscillations and recent progress in studies of muon colliders has triggered interest in considering a neutrino factory at CERN. This paper explains the reference scenario, indicates the other possible choices and mentions the R&D that are foreseen.

Experimental Results Obtained with Air Liquide Cold Compression System: CERN LHC and SNS Projects

NASA Astrophysics Data System (ADS)

Delcayre, F.; Courty, J.-C.; Hamber, F.; Hilbert, B.; Monneret, E.; Toia, J.-L.

2006-04-01

Large scale collider facilities will make intensive use of superconducting magnets, operating below 2.0 K. This dictates high-capacity refrigeration systems operating below 2.0 K. These systems, making use of cryogenic centrifugal compressors in a series arrangement with room temperature screw compressors will be coupled to a refrigerator, providing a certain power at 4.5 K. A first Air Liquide Cold Compression System (CCS) unit was built and delivered to CERN in 2001. Installed at the beginning of 2002, it was commissioned and tested successfully during year 2002. A series of four sets of identical CCS were then tested in 2004. Another set of four cryogenic centrifugal compressors (CCC) has been delivered to Thomas Jefferson National Accelerator Facility (JLAB) for the Spallation Neutron Source (SNS) in 2002. These compressors were tested and commissioned from December 2004 to July 2005. The experimental results obtained with these systems will be presented and discussed: the characteristics of the CCC will be detailed. The principles of control for the CCC in series will be detailed.

CERN launches high-school internship programme

NASA Astrophysics Data System (ADS)

Johnston, Hamish

2017-07-01

The CERN particle-physics lab has hosted 22 high-school students from Hungary in a pilot programme designed to show teenagers how science, technology, engineering and mathematics is used at the particle-physics lab.

Monitoring Evolution at CERN

NASA Astrophysics Data System (ADS)

Andrade, P.; Fiorini, B.; Murphy, S.; Pigueiras, L.; Santos, M.

2015-12-01

Over the past two years, the operation of the CERN Data Centres went through significant changes with the introduction of new mechanisms for hardware procurement, new services for cloud provisioning and configuration management, among other improvements. These changes resulted in an increase of resources being operated in a more dynamic environment. Today, the CERN Data Centres provide over 11000 multi-core processor servers, 130 PB disk servers, 100 PB tape robots, and 150 high performance tape drives. To cope with these developments, an evolution of the data centre monitoring tools was also required. This modernisation was based on a number of guiding rules: sustain the increase of resources, adapt to the new dynamic nature of the data centres, make monitoring data easier to share, give more flexibility to Service Managers on how they publish and consume monitoring metrics and logs, establish a common repository of monitoring data, optimise the handling of monitoring notifications, and replace the previous toolset by new open source technologies with large adoption and community support. This contribution describes how these improvements were delivered, present the architecture and technologies of the new monitoring tools, and review the experience of its production deployment.

Analysis of 440 GeV proton beam-matter interaction experiments at the High Radiation Materials test facility at CERN

NASA Astrophysics Data System (ADS)

Burkart, F.; Schmidt, R.; Raginel, V.; Wollmann, D.; Tahir, N. A.; Shutov, A.; Piriz, A. R.

2015-08-01

In a previous paper [Schmidt et al., Phys. Plasmas 21, 080701 (2014)], we presented the first results on beam-matter interaction experiments that were carried out at the High Radiation Materials test facility at CERN. In these experiments, extended cylindrical targets of solid copper were irradiated with beam of 440 GeV protons delivered by the Super Proton Synchrotron (SPS). The beam comprised of a large number of high intensity proton bunches, each bunch having a length of 0.5 ns with a 50 ns gap between two neighboring bunches, while the length of this entire bunch train was about 7 μs. These experiments established the existence of the hydrodynamic tunneling phenomenon the first time. Detailed numerical simulations of these experiments were also carried out which were reported in detail in another paper [Tahir et al., Phys. Rev. E 90, 063112 (2014)]. Excellent agreement was found between the experimental measurements and the simulation results that validate our previous simulations done using the Large Hadron Collider (LHC) beam of 7 TeV protons [Tahir et al., Phys. Rev. Spec. Top.--Accel. Beams 15, 051003 (2012)]. According to these simulations, the range of the full LHC proton beam and the hadronic shower can be increased by more than an order of magnitude due to the hydrodynamic tunneling, compared to that of a single proton. This effect is of considerable importance for the design of machine protection system for hadron accelerators such as SPS, LHC, and Future Circular Collider. Recently, using metal cutting technology, the targets used in these experiments have been dissected into finer pieces for visual and microscopic inspection in order to establish the precise penetration depth of the protons and the corresponding hadronic shower. This, we believe will be helpful in studying the very important phenomenon of hydrodynamic tunneling in a more quantitative manner. The details of this experimental work together with a comparison with the numerical

Contamination Impact of Station Brush Fire on Cleanroom Facilities

NASA Technical Reports Server (NTRS)

Carey, Phil; Blakkolb, Brian

2010-01-01

Brush and forest fires, both naturally occurring and anthropogenic in origin, in proximity to space flight hardware processing facilities raise concerns about the threat of contamination resulting from airborne particulate and molecular components of smoke. Perceptions of the severity of the threat are possibly heightened by the high sensitivity of the human sense of smell to some components present in the smoke of burning vegetation.On August 26th, 2009, a brushfire broke out north of Pasadena, California, two miles from the Jet Propulsion Laboratory. The Station Fire destroyed over 160,000 acres, coming within a few hundred yards of JPL. Smoke concentrations on Lab were very heavy over several days. All Lab operations were halted, and measures were taken to protect personnel, critical hardware, and facilities. Evaluation of real-time cleanroom monitoring data, visualinspection of facilities, filter systems, and analysis of surface cleanliness samples revealed facility environments andhardware were minimally effected.Outside air quality easily exceeded Class Ten Million. Prefilters captured most large ash and soot; multi-stage filtration greatly minimized the impact on the HEPA/ULPA filters. Air quality in HEPA filtered spacecraft assembly cleanrooms remained within Class 10,000 specification throughout. Surface cleanliness was inimally affected, as large particles were effectively removed from the airstream, and sub-micron particles have extremely long settling rates. Approximate particulate fallout within facilities was 0.00011% area coverage/day compared to 0.00038% area coverage/day during normal operations. Deposition of condensable airborne components, as measured in real time, peaked at approximately1.0 ng/cm2/day compared to 0.05 ng/cm2/day nominal.

Contamination impact of station brush fire on cleanroom facilities

NASA Astrophysics Data System (ADS)

Carey, Philip A.; Blakkolb, Brian K.

2010-08-01

Brush and forest fires, both naturally occurring and anthropogenic in origin, in proximity to space flight hardware processing facilities raise concerns about the threat of contamination resulting from airborne particulate and molecular components of smoke. Perceptions of the severity of the threat are possibly heightened by the high sensitivity of the human sense of smell to some components present in the smoke of burning vegetation. On August 26th, 2009, a brushfire broke out north of Pasadena, California, two miles from the Jet Propulsion Laboratory. The Station Fire destroyed over 160,000 acres, coming within a few hundred yards of JPL. Smoke concentrations on Lab were very heavy over several days. All Lab operations were halted, and measures were taken to protect personnel, critical hardware, and facilities. Evaluation of real-time cleanroom monitoring data, visual inspection of facilities, filter systems, and analysis of surface cleanliness samples revealed facility environments and hardware were minimally effected. Outside air quality easily exceeded Class Ten Million. Prefilters captured most large ash and soot; multi-stage filtration greatly minimized the impact on the HEPA/ULPA filters. Air quality in HEPA filtered spacecraft assembly cleanrooms remained within Class 10,000 specification throughout. Surface cleanliness was minimally affected, as large particles were effectively removed from the airstream, and sub-micron particles have extremely long settling rates. Approximate particulate fallout within facilities was 0.00011% area coverage/day compared to 0.00038% area coverage/day during normal operations. Deposition of condensable airborne components, as measured in real time, peaked at approximately 1.0 ng/cm2/day compared to 0.05 ng/cm2/day nominal.

Integrating Containers in the CERN Private Cloud

NASA Astrophysics Data System (ADS)

Noel, Bertrand; Michelino, Davide; Velten, Mathieu; Rocha, Ricardo; Trigazis, Spyridon

2017-10-01

Containers remain a hot topic in computing, with new use cases and tools appearing every day. Basic functionality such as spawning containers seems to have settled, but topics like volume support or networking are still evolving. Solutions like Docker Swarm, Kubernetes or Mesos provide similar functionality but target different use cases, exposing distinct interfaces and APIs. The CERN private cloud is made of thousands of nodes and users, with many different use cases. A single solution for container deployment would not cover every one of them, and supporting multiple solutions involves repeating the same process multiple times for integration with authentication services, storage services or networking. In this paper we describe OpenStack Magnum as the solution to offer container management in the CERN cloud. We will cover its main functionality and some advanced use cases using Docker Swarm and Kubernetes, highlighting some relevant differences between the two. We will describe the most common use cases in HEP and how we integrated popular services like CVMFS or AFS in the most transparent way possible, along with some limitations found. Finally we will look into ongoing work on advanced scheduling for both Swarm and Kubernetes, support for running batch like workloads and integration of container networking technologies with the CERN infrastructure.

Sustaining the vision for Millennium Development Goal 6, to halt and reverse the spread of HIV/AIDS and other infections.

PubMed

Campbell, Della Dee; Moran, Barbara

2010-01-01

The purpose of Millennium Development Goal 6 is to halt and reverse the spread of HIV/AIDS, malaria, and other diseases and provide universal access to treatment for HIV/AIDS. In this article we describe progress made in meeting the targets for HIV/AIDS set for 2015 and the President's Emergency Plan for AIDS Relief. This funding is geared toward developing sustainable solutions with which to combat diseases that threaten our global community. © 2010 AWHONN, the Association of Women's Health, Obstetric and Neonatal Nurses.

The Evolution of CERN EDMS

NASA Astrophysics Data System (ADS)

Wardzinska, Aleksandra; Petit, Stephan; Bray, Rachel; Delamare, Christophe; Garcia Arza, Griselda; Krastev, Tsvetelin; Pater, Krzysztof; Suwalska, Anna; Widegren, David

2015-12-01

Large-scale long-term projects such as the LHC require the ability to store, manage, organize and distribute large amounts of engineering information, covering a wide spectrum of fields. This information is a living material, evolving in time, following specific lifecycles. It has to reach the next generations of engineers so they understand how their predecessors designed, crafted, operated and maintained the most complex machines ever built. This is the role of CERN EDMS. The Engineering and Equipment Data Management Service has served the High Energy Physics Community for over 15 years. It is CERN's official PLM (Product Lifecycle Management), supporting engineering communities in their collaborations inside and outside the laboratory. EDMS is integrated with the CAD (Computer-aided Design) and CMMS (Computerized Maintenance Management) systems used at CERN providing tools for engineers who work in different domains and who are not PLM specialists. Over the years, human collaborations and machines grew in size and complexity. So did EDMS: it is currently home to more than 2 million files and documents, and has over 6 thousand active users. In April 2014 we released a new major version of EDMS, featuring a complete makeover of the web interface, improved responsiveness and enhanced functionality. Following the results of user surveys and building upon feedback received from key users group, we brought what we think is a system that is more attractive and makes it easy to perform complex tasks. In this paper we will describe the main functions and the architecture of EDMS. We will discuss the available integration options, which enable further evolution and automation of engineering data management. We will also present our plans for the future development of EDMS.

The ISOLDE facility and the HIE-HISOLDE project: Recent highlights

DOE Office of Scientific and Technical Information (OSTI.GOV)

Borge, M. J. G.

2014-07-23

The ISOLDE facility at CERN has as objective the production, study and research of nuclei far from stability. The facility provides low energy radioactive beams and post-accelerated beams. In the last 45 years the ISOLDE facility has gathered unique expertise in research with radioactive beams. Over 700 isotopes of more than 70 elements have been used in a wide range of research domains, including cutting edge studies in nuclear structure, atomic physics, nuclear astrophysics, and fundamental interactions. These nuclear probes are also used to do frontier research in solid state and life sciences. There is an on-going upgrade of themore » facility, the HIE-ISOLDE project, which aims to improve the ISOLDE capabilities in a wide front, from an energy increase of the post-accelerated beam to improvements in beam quality and beam purity. The first phase of HIE-ISOLDE will start for physics in the autumn of 2015 with an upgrade of energy for all post-accelerated ISOLDE beams up to 5.5 MeV/u. In this contribution the most recent highlights of the facility are presented.« less

Building an organic block storage service at CERN with Ceph

NASA Astrophysics Data System (ADS)

van der Ster, Daniel; Wiebalck, Arne

2014-06-01

Emerging storage requirements, such as the need for block storage for both OpenStack VMs and file services like AFS and NFS, have motivated the development of a generic backend storage service for CERN IT. The goals for such a service include (a) vendor neutrality, (b) horizontal scalability with commodity hardware, (c) fault tolerance at the disk, host, and network levels, and (d) support for geo-replication. Ceph is an attractive option due to its native block device layer RBD which is built upon its scalable, reliable, and performant object storage system, RADOS. It can be considered an "organic" storage solution because of its ability to balance and heal itself while living on an ever-changing set of heterogeneous disk servers. This work will present the outcome of a petabyte-scale test deployment of Ceph by CERN IT. We will first present the architecture and configuration of our cluster, including a summary of best practices learned from the community and discovered internally. Next the results of various functionality and performance tests will be shown: the cluster has been used as a backend block storage system for AFS and NFS servers as well as a large OpenStack cluster at CERN. Finally, we will discuss the next steps and future possibilities for Ceph at CERN.

Migration of the CERN IT Data Centre Support System to ServiceNow

NASA Astrophysics Data System (ADS)

Alvarez Alonso, R.; Arneodo, G.; Barring, O.; Bonfillou, E.; Coelho dos Santos, M.; Dore, V.; Lefebure, V.; Fedorko, I.; Grossir, A.; Hefferman, J.; Mendez Lorenzo, P.; Moller, M.; Pera Mira, O.; Salter, W.; Trevisani, F.; Toteva, Z.

2014-06-01

The large potential and flexibility of the ServiceNow infrastructure based on "best practises" methods is allowing the migration of some of the ticketing systems traditionally used for the monitoring of the servers and services available at the CERN IT Computer Centre. This migration enables the standardization and globalization of the ticketing and control systems implementing a generic system extensible to other departments and users. One of the activities of the Service Management project together with the Computing Facilities group has been the migration of the ITCM structure based on Remedy to ServiceNow within the context of one of the ITIL processes called Event Management. The experience gained during the first months of operation has been instrumental towards the migration to ServiceNow of other service monitoring systems and databases. The usage of this structure is also extended to the service tracking at the Wigner Centre in Budapest.

Medical Applications at CERN and the ENLIGHT Network

PubMed Central

Dosanjh, Manjit; Cirilli, Manuela; Myers, Steve; Navin, Sparsh

2016-01-01

State-of-the-art techniques derived from particle accelerators, detectors, and physics computing are routinely used in clinical practice and medical research centers: from imaging technologies to dedicated accelerators for cancer therapy and nuclear medicine, simulations, and data analytics. Principles of particle physics themselves are the foundation of a cutting edge radiotherapy technique for cancer treatment: hadron therapy. This article is an overview of the involvement of CERN, the European Organization for Nuclear Research, in medical applications, with specific focus on hadron therapy. It also presents the history, achievements, and future scientific goals of the European Network for Light Ion Hadron Therapy, whose co-ordination office is at CERN. PMID:26835422

Medical Applications at CERN and the ENLIGHT Network.

PubMed

Dosanjh, Manjit; Cirilli, Manuela; Myers, Steve; Navin, Sparsh

2016-01-01

State-of-the-art techniques derived from particle accelerators, detectors, and physics computing are routinely used in clinical practice and medical research centers: from imaging technologies to dedicated accelerators for cancer therapy and nuclear medicine, simulations, and data analytics. Principles of particle physics themselves are the foundation of a cutting edge radiotherapy technique for cancer treatment: hadron therapy. This article is an overview of the involvement of CERN, the European Organization for Nuclear Research, in medical applications, with specific focus on hadron therapy. It also presents the history, achievements, and future scientific goals of the European Network for Light Ion Hadron Therapy, whose co-ordination office is at CERN.

Commissioning the CERN IT Agile Infrastructure with experiment workloads

NASA Astrophysics Data System (ADS)

Medrano Llamas, Ramón; Harald Barreiro Megino, Fernando; Kucharczyk, Katarzyna; Kamil Denis, Marek; Cinquilli, Mattia

2014-06-01

In order to ease the management of their infrastructure, most of the WLCG sites are adopting cloud based strategies. In the case of CERN, the Tier 0 of the WLCG, is completely restructuring the resource and configuration management of their computing center under the codename Agile Infrastructure. Its goal is to manage 15,000 Virtual Machines by means of an OpenStack middleware in order to unify all the resources in CERN's two datacenters: the one placed in Meyrin and the new on in Wigner, Hungary. During the commissioning of this infrastructure, CERN IT is offering an attractive amount of computing resources to the experiments (800 cores for ATLAS and CMS) through a private cloud interface. ATLAS and CMS have joined forces to exploit them by running stress tests and simulation workloads since November 2012. This work will describe the experience of the first deployments of the current experiment workloads on the CERN private cloud testbed. The paper is organized as follows: the first section will explain the integration of the experiment workload management systems (WMS) with the cloud resources. The second section will revisit the performance and stress testing performed with HammerCloud in order to evaluate and compare the suitability for the experiment workloads. The third section will go deeper into the dynamic provisioning techniques, such as the use of the cloud APIs directly by the WMS. The paper finishes with a review of the conclusions and the challenges ahead.

Stop TB-Halte à la Tuberculose-Canada: engaging industrialised nations in the challenge to meet global targets.

PubMed

Fanning, A; Billo, N; Tannenbaum, T; Phypers, M; Little, C; Graham, B; Mill, J

2004-01-01

The Stop TB Partnership has engaged the 22 high-burden countries in a drive toward the goal of finding 70% of cases and curing 85% by 2005. Traditional partners, aid agencies and governments of industrialised nations have joined the Partnership, but the broader range of civil society remains outside the discourse, risking disinterest on the part of the donor community. Stop TB-Halte à la Tuberculose-Canada was organised to engage new partners to support the Canadian government's commitment to the goal of reducing poverty and diseases of poverty, including tuberculosis, by 50% by 2010. The successes and challenges are explored, and the possibility raised that having a Stop TB movement in every country will ensure that support is sustained and goals of global tuberculosis control reached.

Analysis of 440 GeV proton beam–matter interaction experiments at the High Radiation Materials test facility at CERN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burkart, F.; Schmidt, R.; Wollmann, D.

2015-08-07

In a previous paper [Schmidt et al., Phys. Plasmas 21, 080701 (2014)], we presented the first results on beam–matter interaction experiments that were carried out at the High Radiation Materials test facility at CERN. In these experiments, extended cylindrical targets of solid copper were irradiated with beam of 440 GeV protons delivered by the Super Proton Synchrotron (SPS). The beam comprised of a large number of high intensity proton bunches, each bunch having a length of 0.5 ns with a 50 ns gap between two neighboring bunches, while the length of this entire bunch train was about 7 μs. These experiments established the existencemore » of the hydrodynamic tunneling phenomenon the first time. Detailed numerical simulations of these experiments were also carried out which were reported in detail in another paper [Tahir et al., Phys. Rev. E 90, 063112 (2014)]. Excellent agreement was found between the experimental measurements and the simulation results that validate our previous simulations done using the Large Hadron Collider (LHC) beam of 7 TeV protons [Tahir et al., Phys. Rev. Spec. Top.--Accel. Beams 15, 051003 (2012)]. According to these simulations, the range of the full LHC proton beam and the hadronic shower can be increased by more than an order of magnitude due to the hydrodynamic tunneling, compared to that of a single proton. This effect is of considerable importance for the design of machine protection system for hadron accelerators such as SPS, LHC, and Future Circular Collider. Recently, using metal cutting technology, the targets used in these experiments have been dissected into finer pieces for visual and microscopic inspection in order to establish the precise penetration depth of the protons and the corresponding hadronic shower. This, we believe will be helpful in studying the very important phenomenon of hydrodynamic tunneling in a more quantitative manner. The details of this experimental work together with a comparison with the

Ceremony 25th birthday Cern

ScienceCinema

None

2018-05-18

Celebration of CERN's 25th birthday with a speech by L. Van Hove and J.B. Adams, musical interludes by Ms. Mey and her colleagues (starting with Beethoven). The general managers then proceed with the presentation of souvenirs to members of the personnel who have 25 years of service in the organization. A gesture of recognition is also given to Zwerner.

High intensity neutrino oscillation facilities in Europe

DOE PAGES

Edgecock, T. R.; Caretta, O.; Davenne, T.; ...

2013-02-20

The EUROnu project has studied three possible options for future, high intensity neutrino oscillation facilities in Europe. The first is a Super Beam, in which the neutrinos come from the decay of pions created by bombarding targets with a 4 MW proton beam from the CERN High Power Superconducting Proton Linac. The far detector for this facility is the 500 kt MEMPHYS water Cherenkov, located in the Fréjus tunnel. The second facility is the Neutrino Factory, in which the neutrinos come from the decay of μ + and μ – beams in a storage ring. The far detector in thismore » case is a 100 kt magnetized iron neutrino detector at a baseline of 2000 km. The third option is a Beta Beam, in which the neutrinos come from the decay of beta emitting isotopes, in particular 6He and 18Ne, also stored in a ring. The far detector is also the MEMPHYS detector in the Fréjus tunnel. EUROnu has undertaken conceptual designs of these facilities and studied the performance of the detectors. Based on this, it has determined the physics reach of each facility, in particular for the measurement of CP violation in the lepton sector, and estimated the cost of construction. These have demonstrated that the best facility to build is the Neutrino Factory. Furthermore, if a powerful proton driver is constructed for another purpose or if the MEMPHYS detector is built for astroparticle physics, the Super Beam also becomes very attractive.« less

Measurement and resonance analysis of the 33S(n ,α )30Si cross section at the CERN n_TOF facility in the energy region from 10 to 300 keV

NASA Astrophysics Data System (ADS)

Praena, J.; Sabaté-Gilarte, M.; Porras, I.; Quesada, J. M.; Altstadt, S.; Andrzejewski, J.; Audouin, L.; Bécares, V.; Barbagallo, M.; Bečvář, F.; Belloni, F.; Berthoumieux, E.; Billowes, J.; Boccone, V.; Bosnar, D.; Brugger, M.; Calviño, F.; Calviani, M.; Cano-Ott, D.; Carrapiço, C.; Cerutti, F.; Chiaveri, E.; Chin, M.; Colonna, N.; Cortés, G.; Cortés-Giraldo, M. A.; Diakaki, M.; Dietz, M.; Domingo-Pardo, C.; Dressler, R.; Durán, I.; Eleftheriadis, C.; Ferrari, A.; Fraval, K.; Furman, V.; Göbel, K.; Gómez-Hornillos, M. B.; Ganesan, S.; García, A. R.; Giubrone, G.; Gonçalves, I. F.; González-Romero, E.; Goverdovski, A.; Griesmayer, E.; Guerrero, C.; Gunsing, F.; Heftrich, T.; Hernández-Prieto, A.; Heyse, J.; Jenkins, D. G.; Jericha, E.; Käppeler, F.; Kadi, Y.; Karadimos, D.; Katabuchi, T.; Ketlerov, V.; Khryachkov, V.; Kivel, N.; Koehler, P.; Kokkoris, M.; Kroll, J.; Krtička, M.; Lampoudis, C.; Langer, C.; Leal-Cidoncha, E.; Lederer-Woods, C.; Leeb, H.; Leong, L. S.; Lerendegui-Marco, J.; Losito, R.; Mallick, A.; Manousos, A.; Marganiec, J.; Martínez, T.; Massimi, C.; Mastinu, P.; Mastromarco, M.; Mendoza, E.; Mengoni, A.; Milazzo, P. M.; Mingrone, F.; Mirea, M.; Mondelaers, W.; Paradela, C.; Pavlik, A.; Perkowski, J.; Plompen, A. J. M.; Rauscher, T.; Reifarth, R.; Riego-Perez, A.; Robles, M.; Rubbia, C.; Ryan, J. A.; Sarmento, R.; Saxena, A.; Schillebeeckx, P.; Schmidt, S.; Schumann, D.; Sedyshev, P.; Tagliente, G.; Tain, J. L.; Tarifeño-Saldivia, A.; Tarrío, D.; Tassan-Got, L.; Tsinganis, A.; Valenta, S.; Vannini, G.; Variale, V.; Vaz, P.; Ventura, A.; Vermeulen, M. J.; Vlachoudis, V.; Vlastou, R.; Wallner, A.; Ware, T.; Weigand, M.; Weiss, C.; Wright, T.; Žugec, P.; n TOF Collaboration

2018-06-01

The 33S(n ,α )30Si cross section has been measured at the neutron time-of-flight (n _TOF ) facility at CERN in the neutron energy range from 10 to 300 keV relative to the 10B(n ,α )7Li cross-section standard. Both reactions were measured simultaneously with a set of micromegas detectors. The flight path of 185 m has allowed us to obtain the cross section with high-energy resolution. An accurate description of the resonances has been performed by means of the multilevel multichannel R -matrix code sammy. The results show a significantly higher area of the biggest resonance (13.45 keV) than the unique high-resolution (n ,α ) measurement. The new parametrization of the 13.45-keV resonance is similar to that of the unique transmission measurement. This resonance is a matter of research in neutron-capture therapy. The 33S(n ,α )30Si cross section has been studied in previous works because of its role in the production of 36S in stars, which is currently overproduced in stellar models compared to observations.

Helix Nebula and CERN: A Symbiotic approach to exploiting commercial clouds

NASA Astrophysics Data System (ADS)

Barreiro Megino, Fernando H.; Jones, Robert; Kucharczyk, Katarzyna; Medrano Llamas, Ramón; van der Ster, Daniel

2014-06-01

The recent paradigm shift toward cloud computing in IT, and general interest in "Big Data" in particular, have demonstrated that the computing requirements of HEP are no longer globally unique. Indeed, the CERN IT department and LHC experiments have already made significant R&D investments in delivering and exploiting cloud computing resources. While a number of technical evaluations of interesting commercial offerings from global IT enterprises have been performed by various physics labs, further technical, security, sociological, and legal issues need to be address before their large-scale adoption by the research community can be envisaged. Helix Nebula - the Science Cloud is an initiative that explores these questions by joining the forces of three European research institutes (CERN, ESA and EMBL) with leading European commercial IT enterprises. The goals of Helix Nebula are to establish a cloud platform federating multiple commercial cloud providers, along with new business models, which can sustain the cloud marketplace for years to come. This contribution will summarize the participation of CERN in Helix Nebula. We will explain CERN's flagship use-case and the model used to integrate several cloud providers with an LHC experiment's workload management system. During the first proof of concept, this project contributed over 40.000 CPU-days of Monte Carlo production throughput to the ATLAS experiment with marginal manpower required. CERN's experience, together with that of ESA and EMBL, is providing a great insight into the cloud computing industry and highlighted several challenges that are being tackled in order to ease the export of the scientific workloads to the cloud environments.

CERN: A global project

NASA Astrophysics Data System (ADS)

Voss, Rüdiger

2017-07-01

In the most important shift of paradigm of its membership rules in 60 years, CERN in 2010 introduced a policy of “Geographical Enlargement” which for the first time opened the door for membership of non-European States in the Organization. This short article reviews briefly the history of CERN’s membership rules, discusses the rationale behind the new policy, its relationship with the emerging global roadmap of particle physics, and gives a short overview of the status of the enlargement process.

The high Beta cryo-modules and the associated cryogenic system for the HIE-ISOLDE upgrade at CERN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Delruelle, N.; Leclercq, Y.; Pirotte, O.

2014-01-29

The major upgrade of the energy and intensity of the existing ISOLDE and REX-ISOLDE radioactive ion beam facilities at CERN requires the replacement of most of the existing ISOLDE post-acceleration equipment by a superconducting linac based on quarter-wave resonators housed together with superconducting solenoids in a series of four high-β and two low-β cryo-modules. As well as providing optimum conditions for physics, the cryo-modules need to function under stringent vacuum and cryogenic conditions. We present the detail design and expected cryogenic performance of the high- β cryo-module together with the cryogenic supply and distribution system destined to service the completemore » superconducting linac.« less

Long-term carbon sink in Borneo's forests halted by drought and vulnerable to edge effects.

PubMed

Qie, Lan; Lewis, Simon L; Sullivan, Martin J P; Lopez-Gonzalez, Gabriela; Pickavance, Georgia C; Sunderland, Terry; Ashton, Peter; Hubau, Wannes; Abu Salim, Kamariah; Aiba, Shin-Ichiro; Banin, Lindsay F; Berry, Nicholas; Brearley, Francis Q; Burslem, David F R P; Dančák, Martin; Davies, Stuart J; Fredriksson, Gabriella; Hamer, Keith C; Hédl, Radim; Kho, Lip Khoon; Kitayama, Kanehiro; Krisnawati, Haruni; Lhota, Stanislav; Malhi, Yadvinder; Maycock, Colin; Metali, Faizah; Mirmanto, Edi; Nagy, Laszlo; Nilus, Reuben; Ong, Robert; Pendry, Colin A; Poulsen, Axel Dalberg; Primack, Richard B; Rutishauser, Ervan; Samsoedin, Ismayadi; Saragih, Bernaulus; Sist, Plinio; Slik, J W Ferry; Sukri, Rahayu Sukmaria; Svátek, Martin; Tan, Sylvester; Tjoa, Aiyen; van Nieuwstadt, Mark; Vernimmen, Ronald R E; Yassir, Ishak; Kidd, Petra Susan; Fitriadi, Muhammad; Ideris, Nur Khalish Hafizhah; Serudin, Rafizah Mat; Abdullah Lim, Layla Syaznie; Saparudin, Muhammad Shahruney; Phillips, Oliver L

2017-12-19

Less than half of anthropogenic carbon dioxide emissions remain in the atmosphere. While carbon balance models imply large carbon uptake in tropical forests, direct on-the-ground observations are still lacking in Southeast Asia. Here, using long-term plot monitoring records of up to half a century, we find that intact forests in Borneo gained 0.43 Mg C ha -1 per year (95% CI 0.14-0.72, mean period 1988-2010) above-ground live biomass. These results closely match those from African and Amazonian plot networks, suggesting that the world's remaining intact tropical forests are now en masse out-of-equilibrium. Although both pan-tropical and long-term, the sink in remaining intact forests appears vulnerable to climate and land use changes. Across Borneo the 1997-1998 El Niño drought temporarily halted the carbon sink by increasing tree mortality, while fragmentation persistently offset the sink and turned many edge-affected forests into a carbon source to the atmosphere.

TOWARDS A NOVEL MODULAR ARCHITECTURE FOR CERN RADIATION MONITORING.

PubMed

Boukabache, Hamza; Pangallo, Michel; Ducos, Gael; Cardines, Nicola; Bellotta, Antonio; Toner, Ciarán; Perrin, Daniel; Forkel-Wirth, Doris

2017-04-01

The European Organization for Nuclear Research (CERN) has the legal obligation to protect the public and the people working on its premises from any unjustified exposure to ionising radiation. In this context, radiation monitoring is one of the main concerns of the Radiation Protection Group. After 30 y of reliable service, the ARea CONtroller (ARCON) system is approaching the end of its lifecycle, which raises the need for new, more efficient radiation monitors with a high level of modularity to ensure better maintainability. Based on these two main principles, new detectors are currently being developed that will be capable of measuring very low dose rates down to 50 nSv h-1, whilst being able to measure radiation over an extensive range of 8 decades without any auto scaling. To reach these performances, CERN Radiation MOnitoring Electronics (CROME), the new generation of CERN radiation monitors, is based on the versatile architecture that includes new read-out electronics developed by the Instrumentation and Logistics section of the CERN Radiation Protection Group as well as a reconfigurable system on chip capable of performing complex processing calculations. Beside the capabilities of CROME to continuously measure the ambient dose rate, the system generates radiation alarms, provides interlock signals, drives alarm display units through a fieldbus and provides long-term, permanent and reliable data logging. The measurement tests performed during the first phase of the development show very promising results that pave the way to the second phase: the certification. © The Author 2016. Published by Oxford University Press.

TOWARDS A NOVEL MODULAR ARCHITECTURE FOR CERN RADIATION MONITORING

PubMed Central

Boukabache, Hamza; Pangallo, Michel; Ducos, Gael; Cardines, Nicola; Bellotta, Antonio; Toner, Ciarán; Perrin, Daniel; Forkel-Wirth, Doris

2017-01-01

Abstract The European Organization for Nuclear Research (CERN) has the legal obligation to protect the public and the people working on its premises from any unjustified exposure to ionising radiation. In this context, radiation monitoring is one of the main concerns of the Radiation Protection Group. After 30 y of reliable service, the ARea CONtroller (ARCON) system is approaching the end of its lifecycle, which raises the need for new, more efficient radiation monitors with a high level of modularity to ensure better maintainability. Based on these two main principles, new detectors are currently being developed that will be capable of measuring very low dose rates down to 50 nSv h−1, whilst being able to measure radiation over an extensive range of 8 decades without any auto scaling. To reach these performances, CERN Radiation MOnitoring Electronics (CROME), the new generation of CERN radiation monitors, is based on the versatile architecture that includes new read-out electronics developed by the Instrumentation and Logistics section of the CERN Radiation Protection Group as well as a reconfigurable system on chip capable of performing complex processing calculations. Beside the capabilities of CROME to continuously measure the ambient dose rate, the system generates radiation alarms, provides interlock signals, drives alarm display units through a fieldbus and provides long-term, permanent and reliable data logging. The measurement tests performed during the first phase of the development show very promising results that pave the way to the second phase: the certification. PMID:27909154

WorldWide Web: Hypertext from CERN.

ERIC Educational Resources Information Center

Nickerson, Gord

1992-01-01

Discussion of software tools for accessing information on the Internet focuses on the WorldWideWeb (WWW) system, which was developed at the European Particle Physics Laboratory (CERN) in Switzerland to build a worldwide network of hypertext links using available networking technology. Its potential for use with multimedia documents is also…

Towards a 21st century telephone exchange at CERN

NASA Astrophysics Data System (ADS)

Valentín, F.; Hesnaux, A.; Sierra, R.; Chapron, F.

2015-12-01

The advent of mobile telephony and Voice over IP (VoIP) has significantly impacted the traditional telephone exchange industry—to such an extent that private branch exchanges are likely to disappear completely in the near future. For large organisations, such as CERN, it is important to be able to smooth this transition by implementing new multimedia platforms that can protect past investments and the flexibility needed to securely interconnect emerging VoIP solutions and forthcoming developments such as Voice over LTE (VoLTE). We present the results of ongoing studies and tests at CERN of the latest technologies in this area.

Neutron-induced fission cross section measurement of 233U, 241Am and 243Am in the energy range 0.5 MeV En 20 MeV at n TOF at CERN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Belloni, F.; Milazzo, P. M.; Calviani, M.

2012-01-01

Neutron-induced fission cross section measurements of 233U, 243Am and 241Am relative to 235U have been carried out at the neutron time-of-flight facility n TOF at CERN. A fast ionization chamber has been employed. All samples were located in the same detector; therefore the studied elements and the reference 235U target are subject to the same neutron beam.

The HALT Polycystic Kidney Disease Trials – Analysis of baseline parameters

PubMed Central

Torres, Vicente E.; Chapman, Arlene B.; Perrone, Ronald D.; Bae, K. Ty; Abebe, Kaleab Z.; Bost, James E.; Miskulin, Dana C.; Steinman, Theodore I.; Braun, William; Winklhofer, Franz T.; Hogan, Marie C.; Oskoui, Frederic Rahbari; Kelleher, Cass; Masoumi, Amirali; Glockner, James; Halin, Neil J; Martin, Diego; Remer, Erick; Patel, Nayana.; Pedrosa, Ivan; Wetzel, Louis H.; Thompson, Paul A.; Miller, J. Philip; Meyers, Catherine M.; Schrier, Robert W.

2013-01-01

HALT-PKD consists of two randomized trials comparing treatment with an angiotensin converting inhibitor (ACEI)-angiotensin receptor blocker (ARB) combination vs ACEI alone and standard vs low blood pressure target in Study A (eGFR >60 ml/min/1.73 m2) and ACEI-ARB vs ACEI alone in Study B (eGFR 25-60 ml/min/1.73 m2). It includes the largest cohort of systematically studied ADPKD patients (558 A and 486 B) to date. We used correlation and multiple regression cross-sectional analyses to ascertain associations of baseline parameters with total kidney (TKV) and liver (TLV) or liver cyst (LCV) volumes measured by MRI in Study A and with eGFR in both studies. Lower eGFR and higher natural log transformed urine albumin excretion are independently associated with larger natural log transformed TKV adjusted for height (HtTKV). Higher BSA is independently associated with higher ln(HtTKV) and lower eGFR. Men have larger HtTKV and smaller LCV than women. A weak correlation was found between ln(HtTKV) and ln(HtTLV) or ln(LCV) in women only. Women have higher urine aldosterone excretions and lower plasma potassium levels. In summary, this analysis 1) confirms a strong association between renal volume and functional parameters, 2) shows that gender and other factors differentially affect the development of polycystic disease in the kidney and liver, and 3) suggests an association between anthropomorphic measures reflecting preand/or post-natal growth and the severity of the disease. PMID:22205355

Cryogenic Design of the New High Field Magnet Test Facility at CERN

NASA Astrophysics Data System (ADS)

Benda, V.; Pirotte, O.; De Rijk, G.; Bajko, M.; Craen, A. Vande; Perret, Ph.; Hanzelka, P.

In the framework of the R&D program related to the Large Hadron Collider (LHC) upgrades, a new High Field Magnet (HFM) vertical test bench is required. This facility located in the SM18 cryogenic test hall shall allow testing of up to 15 tons superconducting magnets with energy up to 10 MJ in a temperature range between 1.9 K and 4.5 K. The article describes the cryogenic architecture to be inserted in the general infrastructure of SM18 including the process and instrumentation diagram, the different operating phases including strategy for magnet cool down and warm up at controlled speed and quench management as well as the design of the main components.

CERN - Six Decades of Science, Innovation, Cooperation, and Inspiration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Quigg, Chris

The European Laboratory for Particle Physics, which straddles the Swiss-French border northwest of Geneva, celebrates its sixtieth birthday in 2014 CERN is the preeminent particle-physics institution in the world, currently emphasizing the study of collisions of protons and heavy nuclei at very high energies and the exploration of physics on the electroweak scale (energies where electromagnetism and the weak nuclear force merge). With brilliant accomplishments in research, innovation, and education, and a sustained history of cooperation among people from different countries and cultures, CERN ranks as one of the signal achievements of the postwar European Project. For physicists the worldmore » over, the laboratory is a source of pride and inspiration.« less

HIGH ENERGY PHYSICS: CERN Link Breathes Life Into Russian Physics.

PubMed

Stone, R

2000-10-13

Without fanfare, 600 Russian scientists here at CERN, the European particle physics laboratory, are playing key roles in building the Large Hadron Collider (LHC), a machine that will explore fundamental questions such as why particles have mass, as well as search for exotic new particles whose existence would confirm supersymmetry, a popular theory that aims to unify the four forces of nature. In fact, even though Russia is not one of CERN's 20 member states, most top high-energy physicists in Russia are working on the LHC. Some say their work could prove the salvation of high-energy physics back home.

PARTICLE PHYSICS: CERN Gives Higgs Hunters Extra Month to Collect Data.

PubMed

Morton, O

2000-09-22

After 11 years of banging electrons and positrons together at higher energies than any other machine in the world, CERN, the European laboratory for particle physics, had decided to shut down the Large Electron-Positron collider (LEP) and install a new machine, the Large Hadron Collider (LHC), in its 27-kilometer tunnel. In 2005, the LHC will start bashing protons together at even higher energies. But tantalizing hints of a long-sought fundamental particle have forced CERN managers to grant LEP a month's reprieve.

Development of high efficiency Versatile Arc Discharge Ion Source at CERN ISOLDE.

PubMed

Penescu, L; Catherall, R; Lettry, J; Stora, T

2010-02-01

We report here recent developments of Forced Electron Beam Induced Arc Discharge (FEBIAD) ion sources at the ISOLDE radioactive ion beam facility, hosted at the European Organization for Nuclear Research (CERN). As a result of the propositions to improve the ionization efficiency, two FEBIAD prototypes have been produced and successfully tested in 2008. Off-line studies showed that the 1+ ionization efficiencies for noble gases are 5-20 times larger than with the standard ISOLDE FEBIAD ion sources and reach 60% for radon, which allowed the identification at ISOLDE of (229)Rn, an isotope that had never previously been observed in the laboratory. A factor of 3 increase is also expected for the ionization efficiency of the other elements. The experimental and theoretical methodology is presented. The theoretical model, which gives precise insights on the processes affecting the ionization, is used to design optimal sources (grouped under the name of VADIS--Versatile Arc Discharge Ion Source) for the different chemical classes of the produced isotopes, as already demonstrated for the noble gases.

AAV-mediated Gene Therapy Halts Retinal Degeneration in PDE6β-deficient Dogs

PubMed Central

Pichard, Virginie; Provost, Nathalie; Mendes-Madeira, Alexandra; Libeau, Lyse; Hulin, Philippe; Tshilenge, Kizito-Tshitoko; Biget, Marine; Ameline, Baptiste; Deschamps, Jack-Yves; Weber, Michel; Le Meur, Guylène; Colle, Marie-Anne; Moullier, Philippe; Rolling, Fabienne

2016-01-01

We previously reported that subretinal injection of AAV2/5 RK.cpde6β allowed long-term preservation of photoreceptor function and vision in the rod-cone dysplasia type 1 (rcd1) dog, a large animal model of naturally occurring PDE6β deficiency. The present study builds on these earlier findings to provide a detailed assessment of the long-term effects of gene therapy on the spatiotemporal pattern of retinal degeneration in rcd1 dogs treated at 20 days of age. We analyzed the density distribution of the retinal layers and of particular photoreceptor cells in 3.5-year-old treated and untreated rcd1 dogs. Whereas no rods were observed outside the bleb or in untreated eyes, gene transfer halted rod degeneration in all vector-exposed regions. Moreover, while gene therapy resulted in the preservation of cones, glial cells and both the inner nuclear and ganglion cell layers, no cells remained in vector-unexposed retinas, except in the visual streak. Finally, the retinal structure of treated 3.5-year-old rcd1 dogs was identical to that of unaffected 4-month-old rcd1 dogs, indicating near complete preservation. Our findings indicate that gene therapy arrests the degenerative process even if intervention is initiated after the onset of photoreceptor degeneration, and point to significant potential of this therapeutic approach in future clinical trials. PMID:26857842

AAV-mediated Gene Therapy Halts Retinal Degeneration in PDE6β-deficient Dogs.

PubMed

Pichard, Virginie; Provost, Nathalie; Mendes-Madeira, Alexandra; Libeau, Lyse; Hulin, Philippe; Tshilenge, Kizito-Tshitoko; Biget, Marine; Ameline, Baptiste; Deschamps, Jack-Yves; Weber, Michel; Le Meur, Guylène; Colle, Marie-Anne; Moullier, Philippe; Rolling, Fabienne

2016-05-01

We previously reported that subretinal injection of AAV2/5 RK.cpde6β allowed long-term preservation of photoreceptor function and vision in the rod-cone dysplasia type 1 (rcd1) dog, a large animal model of naturally occurring PDE6β deficiency. The present study builds on these earlier findings to provide a detailed assessment of the long-term effects of gene therapy on the spatiotemporal pattern of retinal degeneration in rcd1 dogs treated at 20 days of age. We analyzed the density distribution of the retinal layers and of particular photoreceptor cells in 3.5-year-old treated and untreated rcd1 dogs. Whereas no rods were observed outside the bleb or in untreated eyes, gene transfer halted rod degeneration in all vector-exposed regions. Moreover, while gene therapy resulted in the preservation of cones, glial cells and both the inner nuclear and ganglion cell layers, no cells remained in vector-unexposed retinas, except in the visual streak. Finally, the retinal structure of treated 3.5-year-old rcd1 dogs was identical to that of unaffected 4-month-old rcd1 dogs, indicating near complete preservation. Our findings indicate that gene therapy arrests the degenerative process even if intervention is initiated after the onset of photoreceptor degeneration, and point to significant potential of this therapeutic approach in future clinical trials.

CERN@school: demonstrating physics with the Timepix detector

NASA Astrophysics Data System (ADS)

Whyntie, T.; Bithray, H.; Cook, J.; Coupe, A.; Eddy, D.; Fickling, R. L.; McKenna, J.; Parker, B.; Paul, A.; Shearer, N.

2015-10-01

This article shows how the Timepix hybrid silicon pixel detector, developed by the Medipix2 Collaboration, can be used by students and teachers alike to demonstrate some key aspects of any well-rounded physics curriculum with CERN@school. After an overview of the programme, the detector's capabilities for measuring and visualising ionising radiation are examined. The classification of clusters - groups of adjacent pixels - is discussed with respect to identifying the different types of particles. Three demonstration experiments - background radiation measurements, radiation profiles and the attenuation of radiation - are described; these can used as part of lessons or as inspiration for independent research projects. Results for exemplar data-sets are presented for reference, as well as details of ongoing research projects inspired by these experiments. Interested readers are encouraged to join the CERN@school Collaboration and so contribute to achieving the programme's aim of inspiring the next generation of scientists and engineers.

High energy density physics effects predicted in simulations of the CERN HiRadMat beam-target interaction experiments

NASA Astrophysics Data System (ADS)

Tahir, N. A.; Burkart, F.; Schmidt, R.; Shutov, A.; Wollmann, D.; Piriz, A. R.

2016-12-01

Experiments have been done at the CERN HiRadMat (High Radiation to Materials) facility in which large cylindrical copper targets were irradiated with 440 GeV proton beam generated by the Super Proton Synchrotron (SPS). The primary purpose of these experiments was to confirm the existence of hydrodynamic tunneling of ultra-relativistic protons and their hadronic shower in solid materials, that was predicted by previous numerical simulations. The experimental measurements have shown very good agreement with the simulation results. This provides confidence in our simulations of the interaction of the 7 TeV LHC (Large Hadron Collider) protons and the 50 TeV Future Circular Collider (FCC) protons with solid materials, respectively. This work is important from the machine protection point of view. The numerical simulations have also shown that in the HiRadMat experiments, a significant part of thetarget material is be converted into different phases of High Energy Density (HED) matter, including two-phase solid-liquid mixture, expanded as well as compressed hot liquid phases, two-phase liquid-gas mixture and gaseous state. The HiRadMat facility is therefore a unique ion beam facility worldwide that is currently available for studying the thermophysical properties of HED matter. In the present paper we discuss the numerical simulation results and present a comparison with the experimental measurements.

Ceremony 25th birthday Cern

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2006-05-08

Célébration du 25ème anniversaire du Cern (jour par jour) avec discours de L.Van Hove et J.B.Adams, des interludes musicals offerts par Mme Mey et ses collègues (au debut 1.mouvement du quatuor avec piano no 3 de L.van Beethoven) Les directeurs généraux procéderont à la remise du souvenir aux membres de personnel ayant 25 années de service dans l'organisation. Un témoignage de reconnaissance est auss fait à l'interprète Mme Zwerner

The ATLAS Experiment at the CERN Large Hadron Collider

NASA Astrophysics Data System (ADS)

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J.; Goossens, L.; Gorbounov, P. A.; Gordeev, A.; Gordon, H.; Gorelov, I.; Gorfine, G.; Gorini, B.; Gorini, E.; Gorišek, A.; Gornicki, E.; Gorokhov, S. A.; Gorski, B. T.; Goryachev, S. V.; Goryachev, V. N.; Gosselink, M.; Gostkin, M. I.; Gouanère, M.; Gough Eschrich, I.; Goujdami, D.; Goulette, M.; Gousakov, I.; Gouveia, J.; Gowdy, S.; Goy, C.; Grabowska-Bold, I.; Grabski, V.; Grafström, P.; Grah, C.; Grahn, K.-J.; Grancagnolo, F.; Grancagnolo, S.; Grassmann, H.; Gratchev, V.; Gray, H. M.; Graziani, E.; Green, B.; Greenall, A.; Greenfield, D.; Greenwood, D.; Gregor, I. M.; Grewal, A.; Griesmayer, E.; Grigalashvili, N.; Grigson, C.; Grillo, A. A.; Grimaldi, F.; Grimm, K.; Gris, P. L. Y.; Grishkevich, Y.; Groenstege, H.; Groer, L. S.; Grognuz, J.; Groh, M.; Gross, E.; Grosse-Knetter, J.; Grothe, M. E. M.; Grudzinski, J.; Gruse, C.; Gruwe, M.; Grybel, K.; Grybos, P.; Gschwendtner, E. M.; Guarino, V. J.; Guicheney, C. J.; Guilhem, G.; Guillemin, T.; Gunther, J.; Guo, B.; Gupta, A.; Gurriana, L.; Gushchin, V. N.; Gutierrez, P.; Guy, L.; Guyot, C.; Gwenlan, C.; Gwilliam, C. B.; Haas, A.; Haas, S.; Haber, C.; Haboubi, G.; Hackenburg, R.; Hadash, E.; Hadavand, H. K.; Haeberli, C.; Härtel, R.; Haggerty, R.; Hahn, F.; Haider, S.; Hajduk, Z.; Hakimi, M.; Hakobyan, H.; Hakobyan, H.; Haller, J.; Hallewell, G. D.; Hallgren, B.; Hamacher, K.; Hamilton, A.; Han, H.; Han, L.; Hanagaki, K.; Hance, M.; Hanke, P.; Hansen, C. J.; Hansen, F. H.; Hansen, J. R.; Hansen, J. B.; Hansen, J. D.; Hansen, P. H.; Hansl-Kozanecka, T.; Hanson, G.; Hansson, P.; Hara, K.; Harder, S.; Harel, A.; Harenberg, T.; Harper, R.; Hart, J. C.; Hart, R. G. G.; Hartjes, F.; Hartman, N.; Haruyama, T.; Harvey, A.; Hasegawa, Y.; Hashemi, K.; Hassani, S.; Hatch, M.; Hatley, R. W.; Haubold, T. G.; Hauff, D.; Haug, F.; Haug, S.; Hauschild, M.; Hauser, R.; Hauviller, C.; Havranek, M.; Hawes, B. M.; Hawkings, R. 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D.; Pimenta Dos Santos, M. A.; Pina, J.; Pinfold, J. L.; Ping, J.; Pinhão, J.; Pinto, B.; Pirotte, O.; Placakyte, R.; Placci, A.; Plamondon, M.; Plano, W. G.; Pleier, M.-A.; Pleskach, A. V.; Podkladkin, S.; Podlyski, F.; Poffenberger, P.; Poggioli, L.; Pohl, M.; Polak, I.; Polesello, G.; Policicchio, A.; Polini, A.; Polychronakos, V.; Pomarede, D. M.; Pommès, K.; Ponsot, P.; Pontecorvo, L.; Pope, B. G.; Popescu, R.; Popovic, D. S.; Poppleton, A.; Popule, J.; Portell Bueso, X.; Posch, C.; Pospelov, G. E.; Pospichal, P.; Pospisil, S.; Postranecky, M.; Potrap, I. N.; Potter, C. J.; Poulard, G.; Pousada, A.; Poveda, J.; Prabhu, R.; Pralavorio, P.; Prasad, S.; Prast, J.; Prat, S.; Prata, M.; Pravahan, R.; Preda, T.; Pretzl, K.; Pribyl, L.; Price, D.; Price, L. E.; Price, M. J.; Prichard, P. M.; Prieur, D.; Primavera, M.; Primor, D.; Prokofiev, K.; Prosso, E.; Proudfoot, J.; Przysiezniak, H.; Puigdengoles, C.; Purdham, J.; Purohit, M.; Puzo, P.; Pylaev, A. N.; Pylypchenko, Y.; Qi, M.; Qian, J.; Qian, W.; Qian, Z.; Qing, D.; Quadt, A.; Quarrie, D. R.; Quayle, W. B.; Rabbers, J. J.; Radeka, V.; Rafi, J. M.; Ragusa, F.; Rahimi, A. M.; Rahm, D.; Raine, C.; Raith, B.; Rajagopalan, S.; Rajek, S.; Rammer, H.; Ramstedt, M.; Rangod, S.; Ratoff, P. N.; Raufer, T.; Rauscher, F.; Rauter, E.; Raymond, M.; Reads, A. L.; Rebuzzi, D.; Redlinger, G. R.; Reeves, K.; Rehak, M.; Reichold, A.; Reinherz-Aronis, E.; Reisinger, I.; Reljic, D.; Rembser, C.; Ren, Z.; Renaudin-Crepe, S. R. C.; Renkel, P.; Rensch, B.; Rescia, S.; Rescigno, M.; Resconi, S.; Resende, B.; Rewiersma, P.; Rey, J.; Rey-Campagnolle, M.; Rezaie, E.; Reznicek, P.; Richards, R. A.; Richer, J.-P.; Richter, R. H.; Richter, R.; Richter-Was, E.; Ridel, M.; Riegler, W.; Rieke, S.; Rijpstra, M.; Rijssenbeek, M.; Rimoldi, A.; Rios, R. R.; Riu Dachs, I.; Rivline, M.; Rivoltella, G.; Rizatdinova, F.; Robertson, S. H.; Robichaud-Veronneau, A.; Robins, S.; Robinson, D.; Robson, A.; Rochford, J. H.; Roda, C.; Rodier, S.; Roe, S.; Røhne, O.; Rohrbach, F.; Roldán, J.; Rolli, S.; Romance, J. B.; Romaniouk, A.; Romanov, V. M.; Romeo, G.; Roos, L.; Ros, E.; Rosati, S.; Rosenbaum, F.; Rosenbaum, G. A.; Rosenberg, E. I.; Rosselet, L.; Rossi, L. P.; Rossi, L.; Rotaru, M.; Rothberg, J.; Rottländer, I.; Rousseau, D.; Rozanov, A.; Rozen, Y.; Ruber, R.; Ruckert, B.; Rudolph, G.; Rühr, F.; Ruggieri, F.; Ruggiero, G.; Ruiz, H.; Ruiz-Martinez, A.; Rulikowska-Zarebska, E.; Rumiantsev, V.; Rumyantsev, L.; Runge, K.; Runolfsson, O.; Rusakovich, N. A.; Rust, D. R.; Rutherfoord, J. P.; Ruwiedel, C.; Ryabov, Y. F.; Ryadovikov, V.; Ryan, P.; Rybkine, G.; da Costa, J. Sá; Saavedra, A. F.; Saboumazrag, S.; F-W Sadrozinski, H.; Sadykov, R.; Sakamoto, H.; Sala, P.; Salamon, A.; Saleem, M.; Salihagic, D.; Salt, J.; Saltó Bauza, O.; Salvachúa Ferrando, B. M.; Salvatore, D.; Salzburger, A.; Sampsonidis, D.; Samset, B. H.; Sánchez Sánchez, C. A.; Sanchis Lozano, M. A.; Sanchis Peris, E.; Sandaker, H.; Sander, H. G.; Sandhoff, M.; Sandvoss, S.; Sankey, D. P. C.; Sanny, B.; Sansone, S.; Sansoni, A.; Santamarina Rios, C.; Santander, J.; Santi, L.; Santoni, C.; Santonico, R.; Santos, J.; Sapinski, M.; Saraiva, J. G.; Sarri, F.; Sasaki, O.; Sasaki, T.; Sasao, N.; Satsounkevitch, I.; Sauvage, D.; Sauvage, G.; Savard, P.; Savine, A. Y.; Savinov, V.; Savoy-Navarro, A.; Savva, P.; Saxon, D. H.; Says, L. P.; Sbarra, C.; Sbrissa, E.; Sbrizzi, A.; Scannicchio, D. A.; Schaarschmidt, J.; Schacht, P.; Schäfer, U.; Schaffer, A. C.; Schaile, D.; Schaller, M.; Schamov, A. G.; Schegelsky, V. A.; Scheirich, D.; Schernau, M.; Scherzer, M. I.; Schiavi, C.; Schick, H.; Schieck, J.; Schieferdecker, P.; Schioppa, M.; Schlager, G.; Schlenker, S.; Schlereth, J. L.; Schmid, P.; Schmidt, M. P.; Schmitt, C.; Schmitt, K.; Schmitz, M.; Schmücker, H.; Schoerner, T.; Scholte, R. C.; Schott, M.; Schouten, D.; Schram, M.; Schricker, A.; Schroff, D.; Schuh, S.; Schuijlenburg, H. W.; Schuler, G.; Schultes, J.; Schultz-Coulon, H.-C.; Schumacher, J.; Schumacher, M.; Schune, Ph; Schwartzman, A.; Schweiger, D.; Schwemling, Ph; Schwick, C.; Schwienhorst, R.; Schwierz, R.; Schwindling, J.; Scott, W. G.; Secker, H.; Sedykh, E.; Seguin-Moreau, N.; Segura, E.; Seidel, S. C.; Seiden, A.; Seixas, J. M.; Sekhniaidze, G.; Seliverstov, D. M.; Selldén, B.; Seman, M.; Semprini-Cesari, N.; Serfon, C.; Serin, L.; Seuster, R.; Severini, H.; Sevior, M. E.; Sexton, K. A.; Sfyrla, A.; Shah, T. P.; Shan, L.; Shank, J. T.; Shapiro, M.; Shatalov, P. B.; Shaver, L.; Shaw, C.; Shears, T. G.; Sherwood, P.; Shibata, A.; Shield, P.; Shilov, S.; Shimojima, M.; Shin, T.; Shiyakova, M.; Shmeleva, A.; Shoa, M.; Shochet, M. J.; Shupe, M. A.; Sicho, P.; Sidoti, A.; Siebel, A.; Siebel, M.; Siegrist, J.; Sijacki, D.; Silva, J.; Silverstein, S. B.; Simak, V.; Simic, Lj; Simion, S.; Simmons, B.; Simonyan, M.; Sinervo, P.; Sipica, V.; Siragusa, G.; Sisakyan, A. N.; Sivoklokov, S.; Sjölin, J.; Skubic, P.; Skvorodnev, N.; Slattery, P.; Slavicek, T.; Sliwa, K.; Sloan, T. J.; Sloper, J.; Smakhtin, V.; Small, A.; Smirnov, S. Yu; Smirnov, Y.; Smirnova, L.; Smirnova, O.; Smith, N. A.; Smith, B. C.; Smith, D. S.; Smith, J.; Smith, K. M.; Smith, B.; Smizanska, M.; Smolek, K.; Snesarev, A. A.; Snow, S. W.; Snow, J.; Snuverink, J.; Snyder, S.; Soares, M.; Soares, S.; Sobie, R.; Sodomka, J.; Söderberg, M.; Soffer, A.; Solans, C. A.; Solar, M.; Sole, D.; Solfaroli Camillocci, E.; Solodkov, A. A.; Solov'yanov, O. V.; Soloviev, I.; Soluk, R.; Sondericker, J.; Sopko, V.; Sopko, B.; Sorbi, M.; Soret Medel, J.; Sosebee, M.; Sosnovtsev, V. V.; Sospedra Suay, L.; Soukharev, A.; Soukup, J.; Spagnolo, S.; Spano, F.; Speckmayer, P.; Spegel, M.; Spencer, E.; Spighi, R.; Spigo, G.; Spila, F.; Spiriti, E.; Spiwoks, R.; Spogli, L.; Spousta, M.; Sprachmann, G.; Spurlock, B.; St. Denis, R. D.; Stahl, T.; Staley, R. J.; Stamen, R.; Stancu, S. N.; Stanecka, E.; Stanek, R. W.; Stanescu, C.; Stapnes, S.; Starchenko, E. A.; Staroba, P.; Stastny, J.; Staude, A.; Stavina, P.; Stavrianakou, M.; Stavropoulos, G.; Stefanidis, E.; Steffens, J. L.; Stekl, I.; Stelzer, H. J.; Stenzel, H.; Stewart, G.; Stewart, T. D.; Stiller, W.; Stockmanns, T.; Stodulski, M.; Stonjek, S.; Stradling, A.; Straessner, A.; Strandberg, J.; Strandlie, A.; Strauss, M.; Strickland, V.; Striegel, D.; Strizenec, P.; Ströhmer, R.; Strom, D. M.; Strong, J. A.; Stroynowski, R.; Stugu, B.; Stumer, I.; Su, D.; Subramania, S.; Suchkov, S. I.; Sugaya, Y.; Sugimoto, T.; Suk, M.; Sulin, V. V.; Sultanov, S.; Sun, Z.; Sundal, B.; Sushkov, S.; Susinno, G.; Sutcliffe, P.; Sutton, M. R.; Sviridov, Yu M.; Sykora, I.; Szczygiel, R. R.; Szeless, B.; Szymocha, T.; Sánchez, J.; Ta, D.; Taboada Gameiro, S.; Tadel, M.; Tafirout, R.; Taga, A.; Takai, H.; Takashima, R.; Takeda, H.; Takeshita, T.; Talby, M.; Talyshev, A.; Tamsett, M. C.; Tanaka, J.; Tanaka, K.; Tanaka, R.; Tanaka, S.; Tanaka, S.; Tanaka, Y.; Tappern, G. P.; Tapprogge, S.; Tarem, S.; Tarrade, F.; Tarrant, J.; Tartarelli, G.; Tas, P.; Tasevsky, M.; Tayalati, Y.; Taylor, F. E.; Taylor, G.; Taylor, G. N.; Taylor, R. P.; Tcherniatine, V.; Tegenfeldt, F.; Teixeira-Dias, P.; Ten Kate, H.; Teng, P. K.; Ter-Antonyan, R.; Terada, S.; Terron, J.; Terwort, M.; Teuscher, R. J.; Tevlin, C. M.; Thadome, J.; Thion, J.; Thioye, M.; Thomas, A.; Thomas, J. P.; Thomas, T. L.; Thomas, E.; Thompson, R. J.; Thompson, A. S.; Thun, R. P.; Tic, T.; Tikhomirov, V. O.; Tikhonov, Y. A.; Timm, S.; Timmermans, C. J. W. P.; Tipton, P.; Tique Aires Viegas, F. J.; Tisserant, S.; Titov, M.; Tobias, J.; Tocut, V. M.; Toczek, B.; Todorova-Nova, S.; Tojo, J.; Tokár, S.; Tokushuku, K.; Tomasek, L.; Tomasek, M.; Tomasz, F.; Tomoto, M.; Tompkins, D.; Tompkins, L.; Toms, K.; Tonazzo, A.; Tong, G.; Tonoyan, A.; Topfel, C.; Topilin, N. D.; Torrence, E.; Torres Pais, J. G.; Toth, J.; Touchard, F.; Tovey, D. R.; Tovey, S. N.; Towndrow, E. F.; Trefzger, T.; Treichel, M.; Treis, J.; Tremblet, L.; Tribanek, W.; Tricoli, A.; Trigger, I. M.; Trilling, G.; Trincaz-Duvoid, S.; Tripiana, M. F.; Trischuk, W.; Trka, Z.; Trocmé, B.; Troncon, C.; C-L Tseng, J.; Tsiafis, I.; Tsiareshka, P. V.; Tsipolitis, G.; Tskhadadze, E. G.; Tsukerman, I. I.; Tsulaia, V.; Tsuno, S.; Turala, M.; Turk Cakir, I.; Turlay, E.; Tuts, P. M.; Twomey, M. S.; Tyndel, M.; Typaldos, D.; Tyrvainen, H.; Tzamarioudaki, E.; Tzanakos, G.; Ueda, I.; Uhrmacher, M.; Ukegawa, F.; Ullán Comes, M.; Unal, G.; Underwood, D. G.; Undrus, A.; Unel, G.; Unno, Y.; Urkovsky, E.; Usai, G.; Usov, Y.; Vacavant, L.; Vacek, V.; Vachon, B.; Vahsen, S.; Valderanis, C.; Valenta, J.; Valente, P.; Valero, A.; Valkar, S.; Valls Ferrer, J. A.; Van der Bij, H.; van der Graaf, H.; van der Kraaij, E.; Van Eijk, B.; van Eldik, N.; van Gemmeren, P.; van Kesteren, Z.; van Vulpen, I.; Van Berg, R.; Vandelli, W.; Vandoni, G.; Vaniachine, A.; Vannucci, F.; Varanda, M.; Varela Rodriguez, F.; Vari, R.; Varnes, E. W.; Varouchas, D.; Vartapetian, A.; Varvell, K. E.; Vassilakopoulos, V. I.; Vassilieva, L.; Vataga, E.; Vaz, L.; Vazeille, F.; Vedrine, P.; Vegni, G.; Veillet, J. J.; Vellidis, C.; Veloso, F.; Veness, R.; Veneziano, S.; Ventura, A.; Ventura, S.; Vercesi, V.; Verducci, M.; Verkerke, W.; Vermeulen, J. C.; Vertogardov, L.; Vetterli, M. C.; Vichou, I.; Vickey, T.; Viehhauser, G. H. A.; Vigeolas, E.; Villa, M.; Villani, E. G.; Villate, J.; Villella, I.; Vilucchi, E.; Vincent, P.; Vincke, H.; Vincter, M. G.; Vinogradov, V. B.; Virchaux, M.; Viret, S.; Virzi, J.; Vitale, A.; Vivarelli, I.; Vives, R.; Vives Vaques, F.; Vlachos, S.; Vogt, H.; Vokac, P.; Vollmer, C. F.; Volpi, M.; Volpini, G.; von Boehn-Buchholz, R.; von der Schmitt, H.; von Toerne, E.; Vorobel, V.; Vorobiev, A. P.; Vorozhtsov, A. S.; Vorozhtsov, S. B.; Vos, M.; Voss, K. C.; Voss, R.; Vossebeld, J. H.; Vovenko, A. S.; Vranjes, N.; Vrba, V.; Vreeswijk, M.; Anh, T. Vu; Vuaridel, B.; Vudragovic, M.; Vuillemin, V.; Vuillermet, R.; Wänanen, A.; Wahlen, H.; Walbersloh, J.; Walker, R.; Walkowiak, W.; Wall, R.; Wallny, R. S.; Walsh, S.; Wang, C.; Wang, J. C.; Wappler, F.; Warburton, A.; Ward, C. P.; Warner, G. P.; Warren, M.; Warsinsky, M.; Wastie, R.; Watkins, P. M.; Watson, A. T.; Watts, G.; Waugh, A. T.; Waugh, B. M.; Weaverdyck, C.; Webel, M.; Weber, G.; Weber, J.; Weber, M.; Weber, P.; Weidberg, A. R.; Weilhammer, P. M.; Weingarten, J.; Weiser, C.; Wellenstein, H.; Wellisch, H. P.; Wells, P. S.; Wemans, A.; Wen, M.; Wenaus, T.; Wendler, S.; Wengler, T.; Wenig, S.; Wermes, N.; Werneke, P.; Werner, P.; Werthenbach, U.; Wheeler-Ellis, S. J.; Whitaker, S. P.; White, A.; White, M. J.; White, S.; Whittington, D.; Wicek, F.; Wicke, D.; Wickens, F. J.; Wiedenmann, W.; Wielers, M.; Wienemann, P.; Wiesmann, M.; Wiesmann, M.; Wijnen, T.; Wildauer, A.; Wilhelm, I.; Wilkens, H. G.; Williams, H. H.; Willis, W.; Willocq, S.; Wilmut, I.; Wilson, J. A.; Wilson, A.; Wingerter-Seez, I.; Winton, L.; Witzeling, W.; Wlodek, T.; Woehrling, E.; Wolter, M. W.; Wolters, H.; Wosiek, B.; Wotschack, J.; Woudstra, M. J.; Wright, C.; Wu, S. L.; Wu, X.; Wuestenfeld, J.; Wunstorf, R.; Xella-Hansen, S.; Xiang, A.; Xie, S.; Xie, Y.; Xu, G.; Xu, N.; Yamamoto, A.; Yamamoto, S.; Yamaoka, H.; Yamazaki, Y.; Yan, Z.; Yang, H.; Yang, J. C.; Yang, S.; Yang, U. K.; Yang, Y.; Yang, Z.; Yao, W.-M.; Yao, Y.; Yarradoddi, K.; Yasu, Y.; Ye, J.; Yilmaz, M.; Yoosoofmiya, R.; Yorita, K.; Yoshida, H.; Yoshida, R.; Young, C.; Youssef, S. P.; Yu, D.; Yu, J.; Yu, M.; Yu, X.; Yuan, J.; Yurkewicz, A.; Zaets, V. G.; Zaidan, R.; Zaitsev, A. M.; Zajac, J.; Zajacova, Z.; Zalite, A. Yu; Zalite, Yo K.; Zanello, L.; Zarzhitsky, P.; Zaytsev, A.; Zdrazil, M.; Zeitnitz, C.; Zeller, M.; Zema, P. F.; Zendler, C.; Zenin, A. V.; Zenis, T.; Zenonos, Z.; Zenz, S.; Zerwas, D.; Zhang, H.; Zhang, J.; Zheng, W.; Zhang, X.; Zhao, L.; Zhao, T.; Zhao, X.; Zhao, Z.; Zhelezko, A.; Zhemchugov, A.; Zheng, S.; Zhichao, L.; Zhou, B.; Zhou, N.; Zhou, S.; Zhou, Y.; Zhu, C. G.; Zhu, H. Z.; Zhuang, X. A.; Zhuravlov, V.; Zilka, B.; Zimin, N. I.; Zimmermann, S.; Ziolkowski, M.; Zitoun, R.; Zivkovic, L.; Zmouchko, V. V.; Zobernig, G.; Zoccoli, A.; Zoeller, M. M.; Zolnierowski, Y.; Zsenei, A.; zur Nedden, M.; Zychacek, V.

2008-08-01

The ATLAS detector as installed in its experimental cavern at point 1 at CERN is described in this paper. A brief overview of the expected performance of the detector when the Large Hadron Collider begins operation is also presented.

The kaon identification system in the NA62 experiment at CERN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Romano, A.

2015-07-01

The main goal of the NA62 experiment at CERN is to measure the branching ratio of the ultra-rare K{sup +} → π{sup +} ν ν-bar decay with 10% accuracy. NA62 will use a 750 MHz high-energy un-separated charged hadron beam, with kaons corresponding to ∼6% of the beam, and a kaon decay-in-flight technique. The positive identification of kaons is performed with a differential Cherenkov detector (CEDAR), filled with Nitrogen gas and placed in the incoming beam. To stand the kaon rate (45 MHz average) and meet the performances required in NA62, the Cherenkov detector has been upgraded (KTAG) with newmore » photon detectors, readout, mechanics and cooling systems. The KTAG provides a fast identification of kaons with an efficiency of at least 95% and precise time information with a resolution below 100 ps. A half-equipped KTAG detector has been commissioned during a technical run at CERN in 2012, while the fully equipped detector, its readout and front-end have been commissioned during a pilot run at CERN in October 2014. The measured time resolution and efficiency are within the required performances. (authors)« less

LHC@Home: a BOINC-based volunteer computing infrastructure for physics studies at CERN

NASA Astrophysics Data System (ADS)

Barranco, Javier; Cai, Yunhai; Cameron, David; Crouch, Matthew; Maria, Riccardo De; Field, Laurence; Giovannozzi, Massimo; Hermes, Pascal; Høimyr, Nils; Kaltchev, Dobrin; Karastathis, Nikos; Luzzi, Cinzia; Maclean, Ewen; McIntosh, Eric; Mereghetti, Alessio; Molson, James; Nosochkov, Yuri; Pieloni, Tatiana; Reid, Ivan D.; Rivkin, Lenny; Segal, Ben; Sjobak, Kyrre; Skands, Peter; Tambasco, Claudia; Veken, Frederik Van der; Zacharov, Igor

2017-12-01

The LHC@Home BOINC project has provided computing capacity for numerical simulations to researchers at CERN since 2004, and has since 2011 been expanded with a wider range of applications. The traditional CERN accelerator physics simulation code SixTrack enjoys continuing volunteers support, and thanks to virtualisation a number of applications from the LHC experiment collaborations and particle theory groups have joined the consolidated LHC@Home BOINC project. This paper addresses the challenges related to traditional and virtualized applications in the BOINC environment, and how volunteer computing has been integrated into the overall computing strategy of the laboratory through the consolidated LHC@Home service. Thanks to the computing power provided by volunteers joining LHC@Home, numerous accelerator beam physics studies have been carried out, yielding an improved understanding of charged particle dynamics in the CERN Large Hadron Collider (LHC) and its future upgrades. The main results are highlighted in this paper.

Highlights from the CERN/ESO/NordForsk ''Gender in Physics Day''

NASA Astrophysics Data System (ADS)

Primas, F.; Guinot, G.; Strandberg, L.

2017-03-01

In their role as observers on the EU Gender Equality Network in the European Research Area (GENERA) project, funded under the Horizon 2020 framework, CERN, ESO and NordForsk joined forces and organised a Gender in Physics Day at the CERN Globe of Science and Innovation. The one-day conference aimed to examine innovative activities promoting gender equality, and to discuss gender-oriented policies and best practice in the European Research Area (with special emphasis on intergovernmental organisations), as well as the importance of building solid networks. The event was very well attended and was declared a success. The main highlights of the meeting are reported.

An Experimental Investigation of Damaged Arresting Gear Tapes for the Langley Aircraft Landing Dynamics Facility

NASA Technical Reports Server (NTRS)

Mason, Angela J.

1999-01-01

An experimental investigation was performed on damaged arresting gear tapes at the Langley Aircraft Landing Dynamics Facility. The arrestment system uses five pairs of tapes to bring the test carriage to a halt. The procedure used to determine when to replace the tapes consists of a close evaluation of each of the 10 tapes after each run. During this evaluation, each tape is examined thoroughly and any damage observed on the tape is recorded. If the damaged tape does not pass the inspection, the tape is replaced with a new one. For the past 13 years, the most commonly seen damage types are edge fray damage and transverse damage. Tests were conducted to determine the maximum tensile strength of a damaged arresting gear tape specimen. The data indicate that tapes exhibiting transverse damage can withstand higher loads than tapes with edge fray damage.

CERN Computing in Commercial Clouds

NASA Astrophysics Data System (ADS)

Cordeiro, C.; Field, L.; Garrido Bear, B.; Giordano, D.; Jones, B.; Keeble, O.; Manzi, A.; Martelli, E.; McCance, G.; Moreno-García, D.; Traylen, S.

2017-10-01

By the end of 2016 more than 10 Million core-hours of computing resources have been delivered by several commercial cloud providers to the four LHC experiments to run their production workloads, from simulation to full chain processing. In this paper we describe the experience gained at CERN in procuring and exploiting commercial cloud resources for the computing needs of the LHC experiments. The mechanisms used for provisioning, monitoring, accounting, alarming and benchmarking will be discussed, as well as the involvement of the LHC collaborations in terms of managing the workflows of the experiments within a multicloud environment.

Cryogenic Control System Migration and Developments towards the UNICOS CERN Standard at INFN

NASA Astrophysics Data System (ADS)

Modanese, Paolo; Calore, Andrea; Contran, Tiziano; Friso, Alessandro; Pengo, Marco; Canella, Stefania; Burioli, Sergio; Gallese, Benedetto; Inglese, Vitaliano; Pezzetti, Marco; Pengo, Ruggero

The cryogenic control systems at Laboratori Nazionali di Legnaro (LNL) are undergoing an important and radical modernization, allowing all the plants controls and supervision systems to be renewed in a homogeneous way towards the CERN-UNICOS standard. Before the UNICOS migration project started there were as many as 7 different types of PLC and 7 different types of SCADA, each one requiring its own particular programming language. In these conditions, even a simple modification and/or integration on the program or on the supervision, required the intervention of a system integrator company, specialized in its specific control system. Furthermore it implied that the operators have to be trained to learn the different types of control systems. The CERN-UNICOS invented for LHC [1] has been chosen due to its reliability and planned to run and be maintained for decades on. The complete migration is part of an agreement between CERN and INFN.

Parathyroidectomy Halts the Deterioration of Renal Function in Primary Hyperparathyroidism.

PubMed

Tassone, Francesco; Guarnieri, Andrea; Castellano, Elena; Baffoni, Claudia; Attanasio, Roberto; Borretta, Giorgio

2015-08-01

Decreased renal function has been consistently included among factors prompting recommendation for surgery in primary hyperparathyroidism (PHPT). However, most retrospective studies addressing this issue did not show an improvement in renal function after parathyroidectomy (PTX). The aim of this study was to investigate changes in renal function after PTX in PHPT patients subdivided according to renal function at diagnosis. This was a retrospective cross-sectional study. We studied 109 consecutive PHPT patients before and after PTX. Biochemical evaluation included fasting total and ionized serum calcium, phosphate, creatinine, immunoreactive intact PTH, and 25-hydroxyvitamin D3 levels. Glomerular filtration rate (GFR) was assessed with the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. Mean (± SD) CKD-EPI estimated GFR (eGFR) at diagnosis was 82.4 ± 19.3 mL/min/1.73 m(2) (median, 84.8 mL/min/1.73 m(2); interquartile range, 68.5-94.2 mL/min/1.73 m(2)). Patients with eGFR equal to or higher than 60 mL/min/1.73 m(2) (group 1, n = 95) were significantly younger than patients with eGFR lower than 60 mL/min/1.73 m(2) (group 2, n = 14; P < .0003). After PTX, eGFR did not change in patients of group 2 (P = .509), whereas it was significantly reduced in patients of group 1 (P < .0002). The difference in eGFR between baseline and post-PTX values was correlated negatively with baseline serum creatinine (R = -0.27; P = .0052) and positively with baseline CKD-EPI eGFR (R = 0.32; P = .00062). At multiple regression analysis, only systolic blood pressure and baseline CKD-EPI eGFR were independent predictors of GFR variation. Surgical cure of PHPT halts renal function deterioration in patients with coexisting renal disease. Our study thus supports the indication for surgery in patients with eGFR less than 60 mL/min/1.73 m(2), as recommended by current guidelines. Moreover, our data show that presurgical renal function is a relevant predictor of renal

CERN openlab: Engaging industry for innovation in the LHC Run 3-4 R&D programme

NASA Astrophysics Data System (ADS)

Girone, M.; Purcell, A.; Di Meglio, A.; Rademakers, F.; Gunne, K.; Pachou, M.; Pavlou, S.

2017-10-01

LHC Run3 and Run4 represent an unprecedented challenge for HEP computing in terms of both data volume and complexity. New approaches are needed for how data is collected and filtered, processed, moved, stored and analysed if these challenges are to be met with a realistic budget. To develop innovative techniques we are fostering relationships with industry leaders. CERN openlab is a unique resource for public-private partnership between CERN and leading Information Communication and Technology (ICT) companies. Its mission is to accelerate the development of cutting-edge solutions to be used by the worldwide HEP community. In 2015, CERN openlab started its phase V with a strong focus on tackling the upcoming LHC challenges. Several R&D programs are ongoing in the areas of data acquisition, networks and connectivity, data storage architectures, computing provisioning, computing platforms and code optimisation and data analytics. This paper gives an overview of the various innovative technologies that are currently being explored by CERN openlab V and discusses the long-term strategies that are pursued by the LHC communities with the help of industry in closing the technological gap in processing and storage needs expected in Run3 and Run4.

Halting Land Subsidence in Tucson, Arizona: Examining the Poroelastic Response to Artificial Recharge

NASA Astrophysics Data System (ADS)

Miller, M. M.; Shirzaei, M.; Argus, D. F.

2017-12-01

Overexploitation of groundwater results in stressed aquifer systems and surface deformation in the form of land subsidence. Differential land subsidence can lead to earth fissures, which threaten buildings and infrastructure. Therefore, careful water management is necessary to ensure aquifer resources are withdrawn and replenished at a sustainable yield to preserve supplies and minimize surface deformation. Tucson, Arizona is a semi-arid desert city that is reliant on a semi-confined alluvial aquifer system for much of the water supply. To understand the poroelastic response of the aquifer system over time, we analyze data from wells equipped with extensometers, InSAR time series, and GPS. From 1990-2005, compaction of fine-grained, aquitard material is measured up to 8.5 mm/yr at well sites equipped with extensometers. This induces permanent aquifer storage volume losses up to 4.1%. Yet, interferograms from Envisat and RadarSAT-2 C-band satellites, which yield multitemporal deformation maps at high resolution, reveal that subsidence remarkably slows by the late 2000s and nearly halts by 2015. We infer this deceleration corresponds to heightened artificial recharge efforts to bank Colorado River water delivered via canal. After groundwater levels recover, residual compaction continues for just a 6.6-year interval, which suggests a high value for vertical hydraulic conductivity up to 9.8 x10-4 m/day. Successful water management and conservation plans help the city preserve existing and replenish depleted groundwater reserves, decelerate land subsidence, and likely reduce the risks associated with earth fissuring.

Preparation of a primary argon beam for the CERN fixed target physics.

PubMed

Küchler, D; O'Neil, M; Scrivens, R; Thomae, R

2014-02-01

The fixed target experiment NA61 in the North Area of the Super Proton Synchrotron is studying phase transitions in strongly interacting matter. Up to now they used the primary beams available from the CERN accelerator complex (protons and lead ions) or fragmented beams created from the primary lead ion beam. To explore a wider range of energies and densities a request was made to provide primary argon and xenon beams. This paper describes the results of the setting up and 10 week test run of the Ar(11+) beam from the 14.5 GHz ECR ion source and the linear accelerator (Linac3) at CERN.

User and group storage management the CMS CERN T2 centre

NASA Astrophysics Data System (ADS)

Cerminara, G.; Franzoni, G.; Pfeiffer, A.

2015-12-01

A wide range of detector commissioning, calibration and data analysis tasks is carried out by CMS using dedicated storage resources available at the CMS CERN Tier-2 centre. Relying on the functionalities of the EOS disk-only storage technology, the optimal exploitation of the CMS user/group resources has required the introduction of policies for data access management, data protection, cleanup campaigns based on access pattern, and long term tape archival. The resource management has been organised around the definition of working groups and the delegation to an identified responsible of each group composition. In this paper we illustrate the user/group storage management, and the development and operational experience at the CMS CERN Tier-2 centre in the 2012-2015 period.

Across Europe to CERN: Taking students on the ultimate physics experience

NASA Astrophysics Data System (ADS)

Wheeler, Sam

2018-05-01

In 2013, I was an Einstein Fellow with the U.S. Department of Energy and I was asked by a colleague, working in a senator's office, if I would join him in a meeting with a physicist to "translate" the science into something more understandable. That meeting turned out to be a wonderful opportunity I would never have otherwise had. During the meeting I met Michael Tuts, a physicist who was working on project ATLAS at CERN. Afterwards, I walked with him out of the Senate office building to Union Station and, in parting, he gave me his card and told me that if I were in Geneva that he could help me get a tour of CERN and the LHC.

PARTICLE PHYSICS: CERN Collider Glimpses Supersymmetry--Maybe.

PubMed

Seife, C

2000-07-14

Last week, particle physicists at the CERN laboratory in Switzerland announced that by smashing together matter and antimatter in four experiments, they detected an unexpected effect in the sprays of particles that ensued. The anomaly is subtle, and physicists caution that it might still be a statistical fluke. If confirmed, however, it could mark the long-sought discovery of a whole zoo of new particles--and the end of a long-standing model of particle physics.

DNS load balancing in the CERN cloud

NASA Astrophysics Data System (ADS)

Reguero Naredo, Ignacio; Lobato Pardavila, Lorena

2017-10-01

Load Balancing is one of the technologies enabling deployment of large-scale applications on cloud resources. A DNS Load Balancer Daemon (LBD) has been developed at CERN as a cost-effective way to balance applications accepting DNS timing dynamics and not requiring persistence. It currently serves over 450 load-balanced aliases with two small VMs acting as master and slave. The aliases are mapped to DNS subdomains. These subdomains are managed with DDNS according to a load metric, which is collected from the alias member nodes with SNMP. During the last years, several improvements were brought to the software, for instance: support for IPv6, parallelization of the status requests, implementing the client in Python to allow for multiple aliases with differentiated states on the same machine or support for application state. The configuration of the Load Balancer is currently managed by a Puppet type. It discovers the alias member nodes and gets the alias definitions from the Ermis REST service. The Aiermis self-service GUI for the management of the LB aliases has been produced and is based on the Ermis service above that implements a form of Load Balancing as a Service (LBaaS). The Ermis REST API has authorisation based in Foreman hostgroups. The CERN DNS LBD is Open Software with Apache 2 license.

Preparation of a primary argon beam for the CERN fixed target physics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Küchler, D., E-mail: detlef.kuchler@cern.ch; O’Neil, M.; Scrivens, R.

2014-02-15

The fixed target experiment NA61 in the North Area of the Super Proton Synchrotron is studying phase transitions in strongly interacting matter. Up to now they used the primary beams available from the CERN accelerator complex (protons and lead ions) or fragmented beams created from the primary lead ion beam. To explore a wider range of energies and densities a request was made to provide primary argon and xenon beams. This paper describes the results of the setting up and 10 week test run of the Ar{sup 11+} beam from the 14.5 GHz ECR ion source and the linear acceleratormore » (Linac3) at CERN.« less

Air liquide 1.8 K refrigeration units for CERN LHC project

NASA Astrophysics Data System (ADS)

Hilbert, Benoît; Gistau-Baguer, Guy M.; Caillaud, Aurélie

2002-05-01

The Large Hadron Collider (LHC) will be CERN's next research instrument for high energy physics. This 27 km long circular accelerator will make intensive use of superconducting magnets, operated below 2.0 K. It will thus require high capacity refrigeration below 2.0 K [1, 2]. Coupled to a refrigerator providing 18 kW equivalent at 4.5 K [3], these systems will be able to absorb a cryogenic power of 2.4 kW at 1.8 K in nominal conditions. Air Liquide has designed one Cold Compressor System (CCS) pre-series for CERN-preceding 3 more of them (among 8 in total located around the machine). These systems, making use of cryogenic centrifugal compressors in a series arrangement coupled to room temperature screw compressors, are presented. Key components characteristics will be given.

Contextualized Magnetism in Secondary School: Learning from the LHC (CERN)

ERIC Educational Resources Information Center

Cid, Ramon

2005-01-01

Physics teachers in secondary schools usually mention the world's largest particle physics laboratory--CERN (European Organization for Nuclear Research)--only because of the enormous size of the accelerators and detectors used there, the number of scientists involved in their activities and also the necessary international scientific…

HALT-D: A Phase II Evaluation of Crofelemer for the Prevention and Prophylaxis of Diarrhea in Patients With Breast Cancer on Pertuzumab-Based Regimens.

PubMed

Gao, Jennifer J; Tan, Ming; Pohlmann, Paula R; Swain, Sandra M

2017-02-01

Approximately 40% to 80% of patients receiving pertuzumab-directed therapy for human epidermal growth factor receptor 2 (HER2)-positive breast cancer will develop chemotherapy-induced diarrhea (CID). Loperamide and octreotide are frequently used to treat CID after diarrhea occurs, but neither is used prophylactically or targets the underlying mechanism. Previous studies suggest blocking epidermal growth factor receptor may cause excess chloride secretion, resulting in diarrhea. Crofelemer is derived from the red latex of the Croton lechleri tree, blocks gastrointestinal cystic fibrosis transmembrane regulator and calcium-activated chloride channels, and is U.S. Food and Drug Administration approved for relief of diarrhea in HIV/AIDS patients on anti-retroviral therapy. Crofelemer is not systemically absorbed, has relatively few side effects, and presents a targeted approach at preventing CID in patients receiving pertuzumab-based therapy. HALT-D (DiarrHeA Prevention and ProphyLaxis with Crofelemer in HER2-Positive Breast Cancer Patients Receiving Trastuzumab, Pertuzumab, and Docetaxel or Paclitaxel with or without Carboplatin, NCT02910219) is a phase II, randomized, open-label trial that aims to recruit 46 patients from 3 MedStar sites. Adults with HER2-positive breast cancer being treated with trastuzumab, pertuzumab, and docetaxel or paclitaxel (THP) or trastuzumab, pertuzumab, docetaxel, and carboplatin (TCHP) will be randomized to receive crofelemer or no medication for diarrhea prophylaxis. The primary endpoint is incidence of all grade diarrhea for ≥ 2 consecutive days during cycles 1 to 2 of THP or TCHP. Secondary endpoints include overall incidence, duration, and severity of diarrhea; time to onset of diarrhea; use of other anti-diarrheal medications; stool frequency and consistency; and quality of life. HALT-D will provide important information about the feasibility and tolerability of crofelemer in preventing diarrhea for patients receiving THP or TCHP

CERN's Common Unix and X Terminal Environment

NASA Astrophysics Data System (ADS)

Cass, Tony

The Desktop Infrastructure Group of CERN's Computing and Networks Division has developed a Common Unix and X Terminal Environment to ease the migration to Unix based Interactive Computing. The CUTE architecture relies on a distributed filesystem—currently Trans arc's AFS—to enable essentially interchangeable client work-stations to access both "home directory" and program files transparently. Additionally, we provide a suite of programs to configure workstations for CUTE and to ensure continued compatibility. This paper describes the different components and the development of the CUTE architecture.

SHiP: a new facility with a dedicated detector to search for new neutral particles and studying tau neutrino properties

NASA Astrophysics Data System (ADS)

Shevchenko, V.

2017-12-01

SHiP (Search for Hidden Particles) is a new general purpose fixed target facility, whose Technical Proposal has been recently reviewed by the CERN SPS Committee and by the CERN Research Board. The two boards recommended that the experiment proceeds further to a Comprehensive Design phase in the context of the new CERNWorking group "Physics Beyond Colliders", aiming at presenting a CERN strategy for the European Strategy meeting of 2019. In the initial phase of SHiP, the 400 GeV proton beam extracted from the SPS will be dumped on a heavy target with the aim of integrating 2×1020 pot in 5 years. A dedicated detector, based on a long vacuum tank followed by a spectrometer and particle identification detectors, will allow probing a variety of models with light long-lived exotic particles and masses below O(10) GeV/c2. The main focus will be the physics of the so-called Hidden Portals, i.e. search for Dark Photons, Light scalars and pseudo-scalars, and Heavy Neutrinos. The sensitivity to Heavy Neutrinos will allow for the first time to probe, in the mass range between the kaon and the charm meson mass, a coupling range for which Baryogenesis and active neutrino masses could also be explained. Another dedicated detector will allow the study of neutrino cross-sections and angular distributions.

Commissioning of the helium cryogenic system for the HIE- ISOLDE accelerator upgrade at CERN

NASA Astrophysics Data System (ADS)

Delruelle, N.; Inglese, V.; Leclercq, Y.; Pirotte, O.; Williams, L.

2015-12-01

The High Intensity and Energy ISOLDE (HIE-ISOLDE) project is a major upgrade of the existing ISOLDE and REX-ISOLDE facilities at CERN. The most significant improvement will come from replacing the existing REX accelerating structure by a superconducting linear accelerator (SC linac) composed ultimately of six cryo-modules installed in series, each containing superconducting RF cavities and solenoids operated at 4.5 K. In order to provide the cooling capacity at all temperature levels between 300 K and 4.5 K for the six cryo-modules, an existing helium refrigerator, manufactured in 1986 and previously used to cool the ALEPH magnet during LEP operation from 1989 to 2000, has been refurbished, reinstalled and recommissioned in a dedicated building located next to the HIE-ISOLDE experimental hall. This helium refrigerator has been connected to a new cryogenic distribution line, consisting of a 30-meter long vacuum-insulated transfer line, a 2000-liter storage dewar and six interconnecting valve boxes, one for each cryo-module. This paper describes the whole cryogenic system and presents the commissioning results including the preliminary operation at 4.5 K of the first cryo- module in the experimental hall.

Highlights from High Energy Neutrino Experiments at CERN

NASA Astrophysics Data System (ADS)

Schlatter, W.-D.

2015-07-01

Experiments with high energy neutrino beams at CERN provided early quantitative tests of the Standard Model. This article describes results from studies of the nucleon quark structure and of the weak current, together with the precise measurement of the weak mixing angle. These results have established a new quality for tests of the electroweak model. In addition, the measurements of the nucleon structure functions in deep inelastic neutrino scattering allowed first quantitative tests of QCD.

The trigger system for K0→2 π0 decays of the NA48 experiment at CERN

NASA Astrophysics Data System (ADS)

Mikulec, I.

1998-02-01

A fully pipelined 40 MHz "dead-time-free" trigger system for neutral K0 decays for the NA48 experiment at CERN is described. The NA48 experiment studies CP-violation using the high intensity beam of the CERN SPS accelerator. The trigger system sums, digitises, filters and processes signals from 13 340 channels of the liquid krypton electro-magnetic calorimeter. In 1996 the calorimeter and part of the trigger electronics were installed and tested. In 1997 the system was completed and prepared to be used in the first NA48 physics data taking period. Cagliari, Cambridge, CERN, Dubna, Edinburgh, Ferrara, Firenze, Mainz, Orsay, Perugia, Pisa, Saclay, Siegen, Torino, Warszawa, Wien Collaboration.

More "Hands-On" Particle Physics: Learning with ATLAS at CERN

ERIC Educational Resources Information Center

Long, Lynne

2011-01-01

This article introduces teachers and students to a new portal of resources called Learning with ATLAS at CERN (http://learningwithatlas-portal.eu/), which has been developed by a European consortium of academic researchers and schools' liaison and outreach providers from countries across Europe. It includes the use of some of the mind-boggling…

The Close AGN Reference Survey (CARS). Mrk 1018 halts dimming and experiences strong short-term variability

NASA Astrophysics Data System (ADS)

Krumpe, M.; Husemann, B.; Tremblay, G. R.; Urrutia, T.; Powell, M.; Davis, T. A.; Scharwächter, J.; Dexter, J.; Busch, G.; Combes, F.; Croom, S. M.; Eckart, A.; McElroy, R. E.; Perez-Torres, M.; Leung, G.

2017-11-01

After changing optical AGN type from 1.9 to 1 in 1984, the AGN Mrk 1018 recently reverted back to its type 1.9 state. Our ongoing monitoring now reveals that the AGN has halted its dramatic dimming, reaching a minimum around October 2016. The minimum was followed by an outburst rising with 0.25 U-band mag/month. The rebrightening lasted at least until February 2017, as confirmed by joint Chandra and Hubble observations. Monitoring was resumed in July 2017 after the source emerged from sunblock, at which point the AGN was found only 0.4 mag brighter than its minimum. The intermittent outburst was accompanied by the appearance of a red wing asymmetry in broad-line shape, indicative of an inhomogeneous broad-line region. The current flickering brightness of Mrk 1018 following its rapid fading either suggests that the source has reignited, remains variable at a low level, or may continue dimming over the next few years. Distinguishing between these possibilities requires continuous multiwavelength monitoring. Based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere under ESO programme(s) 098.B-0672 and 099.B-0159. The scientific results reported in this article are based on observations made by the Chandra X-ray Observatory and the NASA/ESA Hubble Space Telescope.

Clinical Trial of the Potassium Channel Activator Diazoxide for Major Depressive Disorder Halted Due to Intolerability.

PubMed

Kadriu, Bashkim; Yuan, Shiwen; Farmer, Cristan; Nugent, Allison C; Lener, Marc S; Niciu, Mark J; Park, Minkyung; Yazdian, Aaron; Ballard, Elizabeth D; Henn, Fritz A; Henter, Ioline D; Park, Lawrence T; Zarate, Carlos A

2018-06-01

Some glutamatergic modulators have demonstrated rapid and relatively sustained antidepressant properties in patients with major depressive disorder. Because the potassium channel activator diazoxide increases glutamate uptake via potassium channel activation, we hypothesized that it might exert antidepressant effects by increasing the removal of glutamate from the synaptic cleft, thereby reducing excessive glutamate transmission. This randomized, double-blind, placebo-controlled, crossover, single-site inpatient clinical study was conducted at the National Institute of Mental Health to assess the efficacy and safety of a 3-week course of diazoxide (200-400 mg daily, twice a day) versus a 3-week course of placebo in 6 participants with treatment-refractory major depressive disorder. The primary clinical outcome measure was change in Montgomery-Asberg Depression Rating Scale score from baseline to posttreatment. Quantitative insulin sensitivity check index, as well as concomitant imaging measures (electroencephalography, proton magnetic resonance spectroscopy, magnetoencephalography), were used as potential surrogate markers of target (KATP channel) engagement. The study was halted due to severe adverse effects. Given the small sample size, statistical evaluation of the effect of diazoxide on Montgomery-Asberg Depression Rating Scale scores or the imaging measures was not pursued. Visual inspection of the quantitative insulin sensitivity check index test revealed no evidence of target engagement. Although the results are negative, they are an important addition to the literature in this rapidly changing field.

CERN, ESA and ESO Launch "Physics On Stage"

NASA Astrophysics Data System (ADS)

2000-03-01

Physics is everywhere . The laws of physics govern the Universe, the Sun, the Earth and even our own lives. In today's rapidly developing society, we are becoming increasingly dependent on high technology - computers, transport, and communication are just some of the key areas that are the result of discoveries by scientists working in physics. But how much do the citizens of Europe really know about physics? Here is a unique opportunity to learn more about this elusive subject! [Go to Physics On Stage Website] Beginning in February 2000, three major European research organisations are organising a unique Europe-wide programme to raise the public awareness of physics and related sciences. "Physics on Stage" is launched by the European Laboratory for Particle Physics (CERN) , the European Space Agency (ESA) and the European Southern Observatory (ESO) , with support from the European Union. Other partners are the European Physical Society (EPS) and the European Association for Astronomy Education (EAAE). This exciting programme is part of the European Week for Science and Technology and will culminate in a Science Festival during November 6-11, 2000, on the CERN premises at the French-Swiss border near Geneva. Why "Physics on Stage"? The primary goal of "Physics on Stage" is to counteract the current decline in interest and knowledge about physics among Europe's citizens by means of a series of highly visible promotional activities. It will bring together leading scientists and educators, government bodies and the media, to confront the diminishing attraction of physics to young people and to develop strategies to reverse this trend. The objective in the short term is to infuse excitement and to provide new educational materials. In the longer term, "Physics on Stage" will generate new developments by enabling experts throughout Europe to meet, exchange and innovate. "Physics on Stage" in 22 European Countries "Physics on Stage" has been initiated in 22 European

Assessing the rabies control and surveillance systems in Brazil: an experience of measures toward bats after the halt of massive vaccination of dogs and cats in Campinas, Sao Paulo.

PubMed

De Lucca, Tosca; Rodrigues, Ricardo Conde Alves; Castagna, Claudio; Presotto, Douglas; De Nadai, Diego Vinicius; Fagre, Anna; Braga, Guilherme Basseto; Guilloux, Aline Gil Alves; e Alves, Ana Júlia Silva; Martins, Camila Marinelli; Amaku, Marcos; Ferreira, Fernando; Dias, Ricardo Augusto

2013-08-01

Bats are less vulnerable to forest fragmentation than any other mammal, and for that reason, some species can disperse to peri-urban or urban areas. Insectivorous bats are abundant in urban areas due to the density of artificial roosts and insects attracted by city lights. Inter-species transmission of the rabies virus between bats can occur, and this is the most probable mechanism of virus circulation in bat populations. Bats can also transmit the rabies virus to other mammal species, like dogs and cats. With the halt of dog and cat vaccination campaigns in 2010, the importance of rabies surveillance in bats has increased in Brazil. A cross-sectional study performed in Campinas, Sao Paulo State, using data from the passive surveillance system for bats showed that rabies-positive bats from the families Molossidae, Phyllostomidae and Vespertilionidae were found in a peri-urban area. In these areas, dog and cat emergency vaccination (vaccination blockage) was recommended after the halt of the massive vaccination campaign in 2010. This control strategy was able to increase the proportion of vaccinated animals around a critical value of 50% and even with a higher probability of infectious contact between bats and dogs or cats in the vaccination blockage areas, no dog or cat rabies case was observed, evidencing the importance of the implementation of strategic rabies control measures in this new epidemiological scenario. Copyright © 2013 Elsevier B.V. All rights reserved.

Opportunity to Save Historical Railway Infrastructure - Adaptation and Functional Conversion of Facilities

NASA Astrophysics Data System (ADS)

Podwojewska, Magdalena

2017-10-01

After years of neglect and underinvestment, the Polish railways are now witnessing a rapid modernization of both their technical facilities and rolling stock. However, this is true only of the main railway lines connecting major urban complexes. It is worth pointing out that a great number of secondary lines, railway stations and halts still has not been covered by the transformation process. Railway facilities, warehouses and service features are in decay. Rapid technological developments have caused numerous architectural structures of historical interest and service features to fall out of use. There are historical railway facilities dating back to the late 19th or early 20th centuries, whose condition is constantly deteriorating. The only way to save these structures is to change the manner, in which they are being used, and attract new investors and operators. The adaptation of buildings may be carried out in a number of ways by following different strategies. The process depends on the structure’s current condition and significance for the railway network. The facilities which are disused as a result of technological changes in the rolling stock and infrastructure include workshops, steam locomotive bays, turntables and warehouses. Their size and location within a city make them a perfect place for commercial services, exhibitions, heritage sites, concerts and other events attracting great numbers of people. Other strategies may be used for constructions located next to railways lines, whose role has declined. Such constructions include small railway stations, warehouses, reloading and forwarding facilities, railway ramps, railway staff buildings as well as residences for railway employees. Railway stations located at large junctions can handle passenger traffic or freight loading operations. As well as acting as the only window to the world, railway stations in small towns housed all the services available in the place. At the same time, they served as

HST at CERN an Amazing Adventure

NASA Astrophysics Data System (ADS)

Restivo, Evelyn

2009-04-01

The High School Teacher Program (HST) at the European Organization for Nuclear Research, CERN, in Geneva, Switzerland was initiated in 1998 by a group of scientists, as a multicultural international program designed to introduce high school physics teachers to high-energy physics. The goal of the program is to provide experiences and materials that will help teachers lead their students to a better understanding of the physical world. Interacting with physics teachers from around the world leads to new approaches for dealing with educational issues that all teachers encounter. The program includes a variety of tours, a series of lectures and classroom activities about the physics expected from the Large Hadron Collider.

CERN at 60: giant magnet journeys through Geneva

NASA Astrophysics Data System (ADS)

Banks, Michael

2014-07-01

More than 30,000 people descended onto Geneva's harbour last month to celebrate the bicentenary of the city's integration into Switzerland with a parade through the city. Joining the 1200 participants at the Genève200 celebrations were staff from the CERN particle-physics lab, which is located on the outskirts of Geneva, who paraded a superconducting dipole magnet - similar to the thousands used in the Large Hadron Collider - through the city's narrow streets on a 20 m lorry.

DAMPE prototype and its beam test results at CERN

NASA Astrophysics Data System (ADS)

Wu, Jian; Hu, Yiming; Chang, Jin

The first Chinese high energy cosmic particle detector(DAMPE) aims to detect electron/gamma at the range between 5GeV and 10TeV in space. A prototype of this detector is made and tested using both cosmic muons and test beam at CERN. Energy and space resolution as well as strong separation power for electron and proton are shown in the results. The detector structure is illustrated as well.

Cryogenic studies for the proposed CERN large hadron electron collider (LHEC)

NASA Astrophysics Data System (ADS)

Haug, F.; LHeC Study Team, The

2012-06-01

The LHeC (Large Hadron electron Collider) is a proposed future colliding beam facility for lepton-nucleon scattering particle physics at CERN. A new 60 GeV electron accelerator will be added to the existing 27 km circumference 7 TeV LHC for collisions of electrons with protons and heavy ions. Two basic design options are being pursued. The first is a circular accelerator housed in the existing LHC tunnel which is referred to as the "Ring-Ring" version. Low field normal conducting magnets guide the particle beam while superconducting (SC) RF cavities cooled to 2 K are installed at two opposite locations at the LHC tunnel to accelerate the beams. For this version in addition a 10 GeV re-circulating SC injector will be installed. In total four refrigerators with cooling capacities between 1.2 kW and 3 kW @ 4.5 K are needed. The second option, referred to as the "Linac-Ring" version consists of a race-track re-circulating energyrecovery type machine with two 1 km long straight acceleration sections. The 944 high field 2 K SC cavities dissipate 30 kW at CW operation. Eight 10 kW @ 4.5 K refrigerators are proposed. The particle detector contains a combined SC solenoid and dipole forming the cold mass and an independent liquid argon calorimeter. Cooling is done with two individual small sized cryoplants; a 4.5 K helium, and a 87 K liquid nitrogen plant.

Can we spend our way out of the AIDS epidemic? A world halting AIDS model

PubMed Central

2009-01-01

Background There has been a sudden increase in the amount of money donors are willing to spend on the worldwide HIV/AIDS epidemic. Present plans are to hold most of the money in reserve and spend it slowly. However, rapid spending may be the best strategy for halting this disease. Methods We develop a mathematical model that predicts eradication or persistence of HIV/AIDS on a world scale. Dividing the world into regions (continents, countries etc), we develop a linear differential equation model of infectives which has the same eradication properties as more complex models. Results We show that, even if HIV/AIDS can be eradicated in each region independently, travel/immigration of infectives could still sustain the epidemic. We use a continent-level example to demonstrate that eradication is possible if preventive intervention methods (such as condoms or education) reduced the infection rate to two fifths of what it is currently. We show that, for HIV/AIDS to be eradicated within five years, the total cost would be ≈ $63 billion, which is within the existing $60 billion (plus interest) amount raised by the donor community. However, if this action is spread over a twenty year period, as currently planned, then eradication is no longer possible, due to population growth, and the costs would exceed $90 billion. Conclusion Eradication of AIDS is feasible, using the tools that we have currently to hand, but action needs to occur immediately. If not, then HIV/AIDS will race beyond our ability to afford it. PMID:19922685

25th Birthday Cern- Restaurant

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2006-05-05

Cérémonie du 25ème anniversaire du Cern avec plusieurs orateurs et la présence de nombreux autorités cantonales et communales genevoises et personnalités, directeurs généraux, ministres, chercheurs.... Le conseiller féderal et chef du département des affaires étrangères de la confédération Monsieur Pierre Aubert prend la parole pour célébrer à la fois les résultats très remarquables de la coopération internationale en matière scientifique, mais aussi la volonté politique des états européens de mettre en commun leurs ressources pour faire oeuvre d'avenir. Un grand hommage est aussi donné aux deux directeurs disparus, les prof.Bakker et Gregory.

[The CERN and the megascience].

PubMed

Aguilar Peris, José

2006-01-01

In this work we analyse the biggest particle accelerator in the world: the LHC (Large Hadron Collider). The ring shaped tunnel is 27 km long and it is buried over 110 meters underground, straddling the border betwen France and Switzerland at the CERN laboratory near Geneva. Its mission is to recreate the conditions that existed shortly after the Big-Bang and to look for the hypothesised Higgs particle. The LHC will accelerate protons near the speed of the light and collide them head on at an energy of to 14 TeV (1 TeV = 10(12) eV). Keeping such high energy in the proton beams requires enormous magnetic fields which are generated by superconducting electromagnets chilled to less than two degrees above absolute zero. It is expected that LHC will be inaugurated in summer 2007.

SHiP: a new facility with a dedicated detector for studying tau neutrino properties

NASA Astrophysics Data System (ADS)

Komatsu, M.; SHiP Collaboration

2017-06-01

SHiP (Search for Hidden Particles) is a new general purpose fixed target facility at the CERN SPS accelerator, with the aim of search for New Physics which has small coupling with standard particles by searching for long lived beyond standard model particles with masses below a few GeV/c2. The SHiP facility is a high intensity beam bump, the 400GeV proton beam extracted from the SPS will be dumped on a heavy target with the aim of integrating 2 ×1020 pot in 5 years. A dedicated detector, based on the OPERA-like ECC (Emulsion Cloud Chamber), will provide tau and anti-tau neutrino detection capability to study ντ and ν‾τ cross-sections with a statistics a few 100 times larger than the DONUT experiment. Moreover, the structure functions F4 and F5 which is only accessible by tau neutrino interactions can be measured first time. SHiP is the unique chance to study tau and anti tau neutrino properties.

Deployment and Operational Experiences with CernVM-FS at the GridKa Tier-1 Center

NASA Astrophysics Data System (ADS)

Alef, Manfred; Jäger, Axel; Petzold and, Andreas; Verstege, Bernhard

2012-12-01

In 2012 the GridKa Tier-1 computing center hosts 130 kHS06 computing resources and 14PB disk and 17PB tape space. These resources are shared between the four LHC VOs and a number of national and international VOs from high energy physics and other sciences. CernVM-FS has been deployed at GridKa to supplement the existing NFS-based system to access VO software on the worker nodes. It provides a solution tailored to the requirement of the LHC VOs. We will focus on the first operational experiences and the monitoring of CernVM-FS on the worker nodes and the squid caches.

p53 elevation in human cells halt SV40 infection by inhibiting T-ag expression

PubMed Central

Drayman, Nir; Ben-nun-Shaul, Orly; Butin-Israeli, Veronika; Srivastava, Rohit; Rubinstein, Ariel M.; Mock, Caroline S.; Elyada, Ela; Ben-Neriah, Yinon; Lahav, Galit; Oppenheim, Ariella

2016-01-01

SV40 large T-antigen (T-ag) has been known for decades to inactivate the tumor suppressor p53 by sequestration and additional mechanisms. Our present study revealed that the struggle between p53 and T-ag begins very early in the infection cycle. We found that p53 is activated early after SV40 infection and defends the host against the infection. Using live cell imaging and single cell analyses we found that p53 dynamics are variable among individual cells, with only a subset of cells activating p53 immediately after SV40 infection. This cell-to-cell variabilty had clear consequences on the outcome of the infection. None of the cells with elevated p53 at the beginning of the infection proceeded to express T-ag, suggesting a p53-dependent decision between abortive and productive infection. In addition, we show that artificial elevation of p53 levels prior to the infection reduces infection efficiency, supporting a role for p53 in defending against SV40. We further found that the p53-mediated host defense mechanism against SV40 is not facilitated by apoptosis nor via interferon-stimulated genes. Instead p53 binds to the viral DNA at the T-ag promoter region, prevents its transcriptional activation by Sp1, and halts the progress of the infection. These findings shed new light on the long studied struggle between SV40 T-ag and p53, as developed during virus-host coevolution. Our studies indicate that the fate of SV40 infection is determined as soon as the viral DNA enters the nucleus, before the onset of viral gene expression. PMID:27462916

Lead Ions and Coulomb's Law at the LHC (CERN)

ERIC Educational Resources Information Center

Cid-Vidal, Xabier; Cid, Ramon

2018-01-01

Although for most of the time the Large Hadron Collider (LHC) at CERN collides protons, for around one month every year lead ions are collided, to expand the diversity of the LHC research programme. Furthermore, in an effort not originally foreseen, proton-lead collisions are also taking place, with results of high interest to the physics…

25th Birthday Cern- Restaurant

ScienceCinema

None

2017-12-09

Cérémonie du 25ème anniversaire du Cern avec plusieurs orateurs et la présence de nombreux autorités cantonales et communales genevoises et personnalités, directeurs généraux, ministres, chercheurs.... Le conseiller féderal et chef du département des affaires étrangères de la confédération Monsieur Pierre Aubert prend la parole pour célébrer à la fois les résultats très remarquables de la coopération internationale en matière scientifique, mais aussi la volonté politique des états européens de mettre en commun leurs ressources pour faire oeuvre d'avenir. Un grand hommage est aussi donné aux deux directeurs disparus, les prof.Bakker et Gregory.

Data acquisition using the 168/E. [CERN ISR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carroll, J.T.; Cittolin, S.; Demoulin, M.

1983-03-01

Event sizes and data rates at the CERN anti p p collider compose a formidable environment for a high level trigger. A system using three 168/E processors for experiment UA1 real-time event selection is described. With 168/E data memory expanded to 512K bytes, each processor holds a complete event allowing a FORTRAN trigger algorithm access to data from the entire detector. A smart CAMAC interface reads five Remus branches in parallel transferring one word to the target processor every 0.5 ..mu..s. The NORD host computer can simultaneously read an accepted event from another processor.

Radiative neutron capture on 242Pu in the resonance region at the CERN n_TOF-EAR1 facility

NASA Astrophysics Data System (ADS)

Lerendegui-Marco, J.; Guerrero, C.; Mendoza, E.; Quesada, J. M.; Eberhardt, K.; Junghans, A. R.; Krtička, M.; Aberle, O.; Andrzejewski, J.; Audouin, L.; Bécares, V.; Bacak, M.; Balibrea, J.; Barbagallo, M.; Barros, S.; Bečvář, F.; Beinrucker, C.; Berthoumieux, E.; Billowes, J.; Bosnar, D.; Brugger, M.; Caamaño, M.; Calviño, F.; Calviani, M.; Cano-Ott, D.; Cardella, R.; Casanovas, A.; Castelluccio, D. M.; Cerutti, F.; Chen, Y. H.; Chiaveri, E.; Colonna, N.; Cortés, G.; Cortés-Giraldo, M. A.; Cosentino, L.; Damone, L. A.; Diakaki, M.; Dietz, M.; Domingo-Pardo, C.; Dressler, R.; Dupont, E.; Durán, I.; Fernández-Domínguez, B.; Ferrari, A.; Ferreira, P.; Finocchiaro, P.; Furman, V.; Göbel, K.; García, A. R.; Gawlik, A.; Glodariu, T.; Gonçalves, I. F.; González-Romero, E.; Goverdovski, A.; Griesmayer, E.; Gunsing, F.; Harada, H.; Heftrich, T.; Heinitz, S.; Heyse, J.; Jenkins, D. G.; Jericha, E.; Käppeler, F.; Kadi, Y.; Katabuchi, T.; Kavrigin, P.; Ketlerov, V.; Khryachkov, V.; Kimura, A.; Kivel, N.; Kokkoris, M.; Leal-Cidoncha, E.; Lederer, C.; Leeb, H.; Lo Meo, S.; Lonsdale, S. J.; Losito, R.; Macina, D.; Marganiec, J.; Martínez, T.; Massimi, C.; Mastinu, P.; Mastromarco, M.; Matteucci, F.; Maugeri, E. A.; Mengoni, A.; Milazzo, P. M.; Mingrone, F.; Mirea, M.; Montesano, S.; Musumarra, A.; Nolte, R.; Oprea, A.; Patronis, N.; Pavlik, A.; Perkowski, J.; Porras, J. I.; Praena, J.; Rajeev, K.; Rauscher, T.; Reifarth, R.; Riego-Perez, A.; Rout, P. C.; Rubbia, C.; Ryan, J. A.; Sabaté-Gilarte, M.; Saxena, A.; Schillebeeckx, P.; Schmidt, S.; Schumann, D.; Sedyshev, P.; Smith, A. G.; Stamatopoulos, A.; Tagliente, G.; Tain, J. L.; Tarifeño-Saldivia, A.; Tassan-Got, L.; Tsinganis, A.; Valenta, S.; Vannini, G.; Variale, V.; Vaz, P.; Ventura, A.; Vlachoudis, V.; Vlastou, R.; Wallner, A.; Warren, S.; Weigand, M.; Weiss, C.; Wolf, C.; Woods, P. J.; Wright, T.; Žugec, P.; n TOF Collaboration

2018-02-01

The spent fuel of current nuclear reactors contains fissile plutonium isotopes that can be combined with uranium to make mixed oxide (MOX) fuel. In this way the Pu from spent fuel is used in a new reactor cycle, contributing to the long-term sustainability of nuclear energy. However, an extensive use of MOX fuels, in particular in fast reactors, requires more accurate capture and fission cross sections for some Pu isotopes. In the case of 242Pu there are sizable discrepancies among the existing capture cross-section measurements included in the evaluations (all from the 1970s) resulting in an uncertainty as high as 35% in the fast energy region. Moreover, postirradiation experiments evaluated with JEFF-3.1 indicate an overestimation of 14% in the capture cross section in the fast neutron energy region. In this context, the Nuclear Energy Agency (NEA) requested an accuracy of 8% in this cross section in the energy region between 500 meV and 500 keV. This paper presents a new time-of-flight capture measurement on 242Pu carried out at n_TOF-EAR1 (CERN), focusing on the analysis and statistical properties of the resonance region, below 4 keV. The 242Pu(n ,γ ) reaction on a sample containing 95(4) mg enriched to 99.959% was measured with an array of four C6D6 detectors and applying the total energy detection technique. The high neutron energy resolution of n_TOF-EAR1 and the good statistics accumulated have allowed us to extend the resonance analysis up to 4 keV, obtaining new individual and average resonance parameters from a capture cross section featuring a systematic uncertainty of 5%, fulfilling the request of the NEA.

Mapping Remote and Multidisciplinary Learning Barriers: Lessons from "Challenge-Based Innovation" at CERN

ERIC Educational Resources Information Center

Jensen, Matilde Bisballe; Utriainen, Tuuli Maria; Steinert, Martin

2018-01-01

This paper presents the experienced difficulties of students participating in the multidisciplinary, remote collaborating engineering design course challenge-based innovation at CERN. This is with the aim to identify learning barriers and improve future learning experiences. We statistically analyse the rated differences between distinct design…

N° 15-2000: ESA, CERN and ESO launch "Physics on Stage"

NASA Astrophysics Data System (ADS)

2000-03-01

But how much do the citizens of Europe really know about physics? Here is a unique opportunity to learn more about this elusive subject! Beginning in February 2000, three major European research establishments [1] are organising a unique Europe-wide programme to raise the public awareness of physics and related sciences. "Physics on Stage" is launched by the European Space Agency (ESA), the European Laboratory for Particle Physics (CERN), and the European Southern Observatory (ESO), with support from the European Union (EU). Other partners include the European Physical Society (EPS) and the European Association for Astronomy Education (EAAE). This exciting programme is part of the European Week for Science and Technology and will culminate in a Science Festival during November 6-11, 2000, at CERN, Geneva. Why "Physics on Stage"? The primary goal of "Physics on Stage" is to counteract the current decline in interest and knowledge of physics among Europe's citizens by means of a series of highly visible promotional activities. It will bring together leading scientists and educators, government bodies and the media, to confront the diminishing attraction of physics to young people and to develop strategies to reverse this trend. The objective in the short term is to infuse excitement and to provide new educational materials. In the longer term, "Physics on Stage" will generate new developments by enabling experts throughout Europe to meet, exchange and innovate. "Physics on Stage" in 22 European Countries. "Physics on Stage" has been initiated in 22 European countries [2]. In each country, a dedicated National Steering Committee (NSC) is being formed which will be responsible for their own national programme. A list of contact addresses is attached below. "Physics on Stage" is based on a series of high-profile physics-related activities that will inform the European public in general, and European high school physics teachers and media representatives in particular

Active inhibitor-1 maintains protein hyper-phosphorylation in aging hearts and halts remodeling in failing hearts.

PubMed

Pritchard, Tracy J; Kawase, Yoshiaki; Haghighi, Kobra; Anjak, Ahmad; Cai, Wenfeng; Jiang, Min; Nicolaou, Persoulla; Pylar, George; Karakikes, Ioannis; Rapti, Kleopatra; Rubinstein, Jack; Hajjar, Roger J; Kranias, Evangelia G

2013-01-01

Impaired sarcoplasmic reticulum calcium cycling and depressed contractility are key characteristics in heart failure. Defects in sarcoplasmic reticulum function are characterized by decreased SERCA2a Ca-transport that is partially attributable to dephosphorylation of its regulator phospholamban by increased protein phosphatase 1 activity. Inhibition of protein phosphatase 1 through activation of its endogenous inhibitor-1 has been shown to enhance cardiac Ca-handling and contractility as well as protect from pathological stress remodeling in young mice. In this study, we assessed the long-term effects of inducible expression of constitutively active inhibitor-1 in the adult heart and followed function and remodeling through the aging process, up to 20 months. Mice with inhibitor-1 had normal survival and similar function to WTs. There was no overt remodeling as evidenced by measures of left ventricular end-systolic and diastolic diameters and posterior wall dimensions, heart weight to tibia length ratio, and histology. Higher phosphorylation of phospholamban at both Ser16 and Thr17 was maintained in aged hearts with active inhibitor-1, potentially offsetting the effects of elevated Ser2815-phosphorylation in ryanodine receptor, as there were no increases in arrhythmias under stress conditions in 20-month old mice. Furthermore, long-term expression of active inhibitor-1 via recombinant adeno-associated virus type 9 gene transfer in rats with pressure-overload induced heart failure improved function and prevented remodeling, associated with increased phosphorylation of phospholamban at Ser16 and Thr17. Thus, chronic inhibition of protein phosphatase 1, through increases in active inhibitor-1, does not accelerate age-related cardiomyopathy and gene transfer of this molecule in vivo improves function and halts remodeling in the long term.

L-Carnitine halts apoptosis and myelosuppression induced by carboplatin in rat bone marrow cell cultures (BMC).

PubMed

Abd-Allah, Adel R A; Al-Majed, Abdulhakeem A; Al-Yahya, Abdulaziz A; Fouda, Soliman I; Al-Shabana, Othman A

2005-07-01

Carboplatin (CP), a second generation platinum compound, is effective against various types of cancers, producing less nephrotoxicity and ototoxicity but more myelotoxicity than cisplatinum. CP-myelosuppression is the rate-limiting step of its clinical use. Prevention of CP-myelosuppression is a major target in the field of chemotherapy. Therefore, the present study investigates the use of L-carnitine (LCR)-an antioxidant, cardioprotective, neuroprotective, and immunostimulant nontoxic natural compound-to protect against CP-induced myelosuppression. The viability of BMC was studied using a trypan blue exclusion technique following incubation with CP and/or LCR as a function of time and concentration. Apoptosis was tested for by detecting the amount of DNA fragmentation and the visualization of DNA ladders upon gel electrophoresis. Bone marrow progenitor cell function was examined by colony forming unit assay. Cellular contents of glutathione (GSH) and malondialdehyde (MDA) were also estimated. Results revealed that LC50 of CP is 4.7 mM and the highest safe concentration of LCR is 5 mM. Co-exposure of LCR+CP rescued BMC viability by 37% compared to the CP-treated cultures. The LCR halts CP-induced apoptosis and it significantly improves the function of the bone marrow progenitors by increasing the number of colony-forming units as a response to granulocyte/macrophage colony stimulating factors. Finally, LCR restores CP-induced GSH depletion and prevents MDA elevation in BMC. In summary, the results suggest that LCR is able to protect against CP-induced myelosuppression, which suggests its use as an adjuvant therapy. This finding merits further investigation into the mechanism(s) of such protection as well as its interaction with CP antitumor activity.

High-accuracy determination of the neutron flux in the new experimental area n_TOF-EAR2 at CERN

NASA Astrophysics Data System (ADS)

Sabaté-Gilarte, M.; Barbagallo, M.; Colonna, N.; Gunsing, F.; Žugec, P.; Vlachoudis, V.; Chen, Y. H.; Stamatopoulos, A.; Lerendegui-Marco, J.; Cortés-Giraldo, M. A.; Villacorta, A.; Guerrero, C.; Damone, L.; Audouin, L.; Berthoumieux, E.; Cosentino, L.; Diakaki, M.; Finocchiaro, P.; Musumarra, A.; Papaevangelou, T.; Piscopo, M.; Tassan-Got, L.; Aberle, O.; Andrzejewski, J.; Bécares, V.; Bacak, M.; Baccomi, R.; Balibrea, J.; Barros, S.; Bečvář, F.; Beinrucker, C.; Belloni, F.; Billowes, J.; Bosnar, D.; Brugger, M.; Caamaño, M.; Calviño, F.; Calviani, M.; Cano-Ott, D.; Cardella, R.; Casanovas, A.; Castelluccio, D. M.; Cerutti, F.; Chiaveri, E.; Cortés, G.; Deo, K.; Domingo-Pardo, C.; Dressler, R.; Dupont, E.; Durán, I.; Fernández-Domínguez, B.; Ferrari, A.; Ferreira, P.; Frost, R. J. W.; Furman, V.; Göbel, K.; García, A. R.; Gawlik, A.; Gheorghe, I.; Glodariu, T.; Gonçalves, I. F.; González, E.; Goverdovski, A.; Griesmayer, E.; Harada, H.; Heftrich, T.; Heinitz, S.; Hernández-Prieto, A.; Heyse, J.; Jenkins, D. G.; Jericha, E.; Käppeler, F.; Kadi, Y.; Katabuchi, T.; Kavrigin, P.; Ketlerov, V.; Khryachkov, V.; Kimura, A.; Kivel, N.; Kokkoris, M.; Krtička, M.; Leal-Cidoncha, E.; Lederer, C.; Leeb, H.; Licata, M.; Lo Meo, S.; Lonsdale, S. J.; Losito, R.; Macina, D.; Marganiec, J.; Martínez, T.; Massimi, C.; Mastinu, P.; Mastromarco, M.; Matteucci, F.; Maugeri, E. A.; Mendoza, E.; Mengoni, A.; Milazzo, P. M.; Mingrone, F.; Mirea, M.; Montesano, S.; Nolte, R.; Oprea, A.; Palomo-Pinto, F. R.; Paradela, C.; Patronis, N.; Pavlik, A.; Perkowski, J.; Porras, J. I.; Praena, J.; Quesada, J. M.; Rajeev, K.; Rauscher, T.; Reifarth, R.; Riego-Perez, A.; Robles, M. S.; Rout, P. C.; Rubbia, C.; Ryan, J. A.; Saxena, A.; Schillebeeckx, P.; Schmidt, S.; Schumann, D.; Sedyshev, P.; Smith, A. G.; Suryanarayana, S. V.; Tagliente, G.; Tain, J. L.; Tarifeño-Saldivia, A.; Tsinganis, A.; Valenta, S.; Vannini, G.; Variale, V.; Vaz, P.; Ventura, A.; Vlastou, R.; Wallner, A.; Warren, S.; Weigand, M.; Wolf, C.; Woods, P. J.; Weiss, C.; Wright, T.

2017-10-01

A new high flux experimental area has recently become operational at the n_TOF facility at CERN. This new measuring station, n_TOF-EAR2, is placed at the end of a vertical beam line at a distance of approximately 20m from the spallation target. The characterization of the neutron beam, in terms of flux, spatial profile and resolution function, is of crucial importance for the feasibility study and data analysis of all measurements to be performed in the new area. In this paper, the measurement of the neutron flux, performed with different solid-state and gaseous detection systems, and using three neutron-converting reactions considered standard in different energy regions is reported. The results of the various measurements have been combined, yielding an evaluated neutron energy distribution in a wide energy range, from 2meV to 100MeV, with an accuracy ranging from 2%, at low energy, to 6% in the high-energy region. In addition, an absolute normalization of the n_TOF-EAR2 neutron flux has been obtained by means of an activation measurement performed with 197Au foils in the beam.

National borders effectively halt the spread of rabies: the current rabies epidemic in China is dislocated from cases in neighboring countries.

PubMed

Guo, Zhenyang; Tao, Xiaoyan; Yin, Cuiping; Han, Na; Yu, Jinning; Li, Hao; Liu, Haizhou; Fang, Wei; Adams, James; Wang, Jun; Liang, Guodong; Tang, Qing; Rayner, Simon

2013-01-01

China has seen a massive resurgence of rabies cases in the last 15 years with more than 25,000 human fatalities. Initial cases were reported in the southwest but are now reported in almost every province. There have been several phylogenetic investigations into the origin and spread of the virus within China but few reports investigating the impact of the epidemic on neighboring countries. We therefore collected nucleoprotein sequences from China and South East Asia and investigated their phylogenetic and phylogeographic relationship. Our results indicate that within South East Asia, isolates mainly cluster according to their geographic origin. We found evidence of sporadic exchange of strains between neighboring countries, but it appears that the major strain responsible for the current Chinese epidemic has not been exported. This suggests that national geographical boundaries and border controls are effective at halting the spread of rabies from China into adjacent regions. We further investigated the geographic structure of Chinese sequences and found that the current epidemic is dominated by variant strains that were likely present at low levels in previous domestic epidemics. We also identified epidemiological linkages between high incidence provinces consistent with observations based on surveillance data from human rabies cases.

30 CFR 285.802 - What must I do if I discover a potential archaeological resource while conducting my approved...

Code of Federal Regulations, 2011 CFR

2011-07-01

... OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Environmental and... your project, you must: (1) Immediately halt all seafloor-disturbing activities within the area of the...

Determining the structure of Higgs couplings at the CERN LargeHadron Collider.

PubMed

Plehn, Tilman; Rainwater, David; Zeppenfeld, Dieter

2002-02-04

Higgs boson production via weak boson fusion at the CERN Large Hadron Collider has the capability to determine the dominant CP nature of a Higgs boson, via the tensor structure of its coupling to weak bosons. This information is contained in the azimuthal angle distribution of the two outgoing forward tagging jets. The technique is independent of both the Higgs boson mass and the observed decay channel.

Taking Energy to the Physics Classroom from the Large Hadron Collider at CERN

ERIC Educational Resources Information Center

Cid, Xabier; Cid, Ramon

2009-01-01

In 2008, the greatest experiment in history began. When in full operation, the Large Hadron Collider (LHC) at CERN will generate the greatest amount of information that has ever been produced in an experiment before. It will also reveal some of the most fundamental secrets of nature. Despite the enormous amount of information available on this…

News Conference: Serbia hosts teachers' seminar Resources: Teachers TV website closes for business Festival: Science takes to the stage in Denmark Research: How noise affects learning in secondary schools CERN: CERN visit inspires new teaching ideas Education: PLS aims to improve perception of science for school students Conference: Scientix conference discusses challenges in science education

NASA Astrophysics Data System (ADS)

2011-07-01

Conference: Serbia hosts teachers' seminar Resources: Teachers TV website closes for business Festival: Science takes to the stage in Denmark Research: How noise affects learning in secondary schools CERN: CERN visit inspires new teaching ideas Education: PLS aims to improve perception of science for school students Conference: Scientix conference discusses challenges in science education

News Particle Physics: ATLAS unveils mural at CERN Prize: Corti Trust invites essay entries Astrophysics: CERN holds cosmic-ray conference Researchers in Residence: Lord Winston returns to school Music: ATLAS scientists record physics music Conference: Champagne flows at Reims event Competition: Students triumph at physics olympiad Teaching: Physics proves popular in Japanese schools Forthcoming Events

NASA Astrophysics Data System (ADS)

2011-01-01

Particle Physics: ATLAS unveils mural at CERN Prize: Corti Trust invites essay entries Astrophysics: CERN holds cosmic-ray conference Researchers in Residence: Lord Winston returns to school Music: ATLAS scientists record physics music Conference: Champagne flows at Reims event Competition: Students triumph at physics olympiad Teaching: Physics proves popular in Japanese schools Forthcoming Events

OPENMED: A facility for biomedical experiments based on the CERN Low Energy Ion Ring (LEIR)

NASA Astrophysics Data System (ADS)

Carli, Christian

At present protons and carbon ions are in clinical use for hadron therapy at a growing number of treatment centers all over the world. Nevertheless, only limited direct clinical evidence of their superiority over other forms of radiotherapy is available [1]. Furthermore fundamental studies on biological effects of hadron beams have been carried out at different times (some a long time ago) in different laboratories and under different conditions. Despite an increased availability of ion beams for hadron therapy, beam time for preclinical studies is expected to remain insufficient as the priority for therapy centers is to treat the maximum number of patients. Most of the remaining beam time is expected to be required for setting up and measurements to guarantee appropriate good quality beams for treatments. The proposed facility for biomedical research [2] in support of hadron therapy centers would provide ion beams for interested research groups and allow them to carry out basic studies under well defined conditions. Typical studies would include radiobiological phenomena like relative biological effectiveness with different energies, ion species, and intensities. Furthermore possible studies include the development of advanced dosimetry in heterogeneous materials that resemble the human body, imaging techniques and, at a later stage, when the maximum energy with the LEIR magnets can be reached, fragmentation.

Measurement of the inclusive jet cross section at the CERN pp collider

NASA Astrophysics Data System (ADS)

Arnison, G.; Albrow, M. G.; Allkofer, O. C.; Astbury, A.; Aubert, B.; Bacci, C.; Batley, J. R.; Bauer, G.; Bettini, A.; Bézaguet, A.; Bock, R. K.; Bos, K.; Buckley, E.; Bunn, J.; Busetto, G.; Catz, P.; Cennini, P.; Centro, S.; Ceradini, F.; Ciapetti, G.; Cittolin, S.; Clarke, D.; Cline, D.; Cochet, C.; Colas, J.; Colas, P.; Corden, M.; Cox, G.; Dallman, D.; Dau, D.; Debeer, M.; Debrion, J. P.; Degiorgi, M.; della Negra, M.; Demoulin, M.; Denby, B.; Denegri, D.; Diciaccio, A.; Dobrzynski, L.; Dorenbosch, J.; Dowell, J. D.; Duchovni, E.; Edgecock, R.; Eggert, K.; Eisenhandler, E.; Ellis, N.; Erhard, P.; Faissner, H.; Fince Keeler, M.; Flynn, P.; Fontaine, G.; Frey, R.; Frühwirth, R.; Garvey, J.; Gee, D.; Geer, S.; Ghesquière, C.; Ghez, P.; Ghio, F.; Giacomelli, P.; Gibson, W. R.; Giraud-Héraud, Y.; Givernaud, A.; Gonidec, A.; Goodman, M.; Grassmann, H.; Grayer, G.; Guryn, W.; Hansl-Kozanecka, T.; Haynes, W.; Haywood, S. J.; Hoffmann, H.; Holthuizen, D. J.; Homer, R. J.; Homer, R. J.; Honma, A.; Jank, W.; Jimack, M.; Jorat, G.; Kalmus, P. I. P.; Karimäri, V.; Keeler, R.; Kenyon, I.; Kernan, A.; Kienzle, W.; Kinnunen, R.; Kozanecki, W.; Kroll, J.; Kryn, D.; Kyberd, P.; Lacava, F.; Laugier, J. P.; Lees, J. P.; Leuchs, R.; Levegrun, S.; Lévêque, A.; Levi, M.; Linglin, D.; Locci, E.; Long, K.; Markiewicz, T.; Markytan, M.; Martin, T.; Maurin, F.; McMahon, T.; Mendiburu, J.-P.; Meneguzzo, A.; Meyer, O.; Meyer, T.; Minard, M.-N.; Mohammadi, M.; Morgan, K.; Moricca, M.; Moser, H.; Mours, B.; Muller, Th.; Nandi, A.; Naumann, L.; Norton, A.; Paoluzi, L.; Pascoli, D.; Pauss, F.; Perault, C.; Piano Mortari, G.; Pietarinen, E.; Pigot, C.; Pimiä, M.; Pitman, D.; Placci, A.; Porte, J.-P.; Radermacher, E.; Ransdell, J.; Redelberger, T.; Reithler, H.; Revol, J. P.; Richman, J.; Rijssenbeek, M.; Rohlf, J.; Rossi, P.; Roberts, C.; Ruhm, W.; Rubbia, C.; Sajot, G.; Salvini, G.; Sass, J.; Sadoulet, B.; Samyn, D.; Savoy-Navarro, A.; Schinzel, D.; Schwartz, A.; Scott, W.; Scott, W.; Shah, T. P.; Sheer, I.; Siotis, I.; Smith, D.; Sobie, R.; Sphicas, P.; Strauss, J.; Streets, J.; Stubenrauch, C.; Summers, D.; Sumorok, K.; Szonczo, F.; Tao, C.; Ten Have, I.; Thompson, G.; Tscheslog, E.; Tuominiemi, J.; van Eijk, B.; Verecchia, P.; Vialle, J. P.; Virdee, T. S.; von der Schmitt, H.; von Schlippe, W.; Vrana, J.; Vuillemin, V.; Wahl, H. D.; Watkins, P.; Wilke, R.; Wilson, J.; Wingerter, I.; Wimpenny, S. J.; Wulz, C.-E.; Wyatt, T.; Yvert, M.; Zacharov, I.; Zaganidis, N.; Zanello, L.; Zotto, P.

1986-05-01

The inclusive jet cross section has been measured in the UA1 experiment at the CERN pp Collider at centre-of-mass energies √s = 546 GeV and √s = 630 eV. The cross sections are found to be consistent with QCD predictions, The observed change in the cross section with the centre-of-mass energy √s is accounted for in terms of xT scaling.

National Borders Effectively Halt the Spread of Rabies: The Current Rabies Epidemic in China Is Dislocated from Cases in Neighboring Countries

PubMed Central

Guo, Zhenyang; Tao, Xiaoyan; Yin, Cuiping; Han, Na; Yu, Jinning; Li, Hao; Liu, Haizhou; Fang, Wei; Adams, James; Wang, Jun; Liang, Guodong; Tang, Qing; Rayner, Simon

2013-01-01

China has seen a massive resurgence of rabies cases in the last 15 years with more than 25,000 human fatalities. Initial cases were reported in the southwest but are now reported in almost every province. There have been several phylogenetic investigations into the origin and spread of the virus within China but few reports investigating the impact of the epidemic on neighboring countries. We therefore collected nucleoprotein sequences from China and South East Asia and investigated their phylogenetic and phylogeographic relationship. Our results indicate that within South East Asia, isolates mainly cluster according to their geographic origin. We found evidence of sporadic exchange of strains between neighboring countries, but it appears that the major strain responsible for the current Chinese epidemic has not been exported. This suggests that national geographical boundaries and border controls are effective at halting the spread of rabies from China into adjacent regions. We further investigated the geographic structure of Chinese sequences and found that the current epidemic is dominated by variant strains that were likely present at low levels in previous domestic epidemics. We also identified epidemiological linkages between high incidence provinces consistent with observations based on surveillance data from human rabies cases. PMID:23383359

The ELENA facility

NASA Astrophysics Data System (ADS)

Bartmann, Wolfgang; Belochitskii, Pavel; Breuker, Horst; Butin, Francois; Carli, Christian; Eriksson, Tommy; Oelert, Walter; Ostojic, Ranko; Pasinelli, Sergio; Tranquille, Gerard

2018-03-01

The CERN Antiproton Decelerator (AD) provides antiproton beams with a kinetic energy of 5.3 MeV to an active user community. The experiments would profit from a lower beam energy, but this extraction energy is the lowest one possible under good conditions with the given circumference of the AD. The Extra Low Energy Antiproton ring (ELENA) is a small synchrotron with a circumference a factor of 6 smaller than the AD to further decelerate antiprotons from the AD from 5.3 MeV to 100 keV. Controlled deceleration in a synchrotron equipped with an electron cooler to reduce emittances in all three planes will allow the existing AD experiments to increase substantially their antiproton capture efficiencies and render new experiments possible. ELENA ring commissioning is taking place at present and first beams to a new experiment installed in a new experimental area are foreseen in 2017. The transfer lines from ELENA to existing experiments in the old experimental area will be installed during CERN Long Shutdown 2 (LS2) in 2019 and 2020. The status of the project and ring commissioning will be reported. This article is part of the Theo Murphy meeting issue `Antiproton physics in the ELENA era'.

Measurement of the 241Am neutron capture cross section at the n_TOF facility at CERN

NASA Astrophysics Data System (ADS)

Mendoza, E.; Cano-Ott, D.; Altstadt, S.; Andriamonje, S.; Andrzejewski, J.; Audouin, L.; Balibrea, J.; Bécares, V.; Barbagallo, M.; Bečvář, F.; Belloni, F.; Berthier, B.; Berthoumieux, E.; Billowes, J.; Boccone, V.; Bosnar, D.; Brugger, M.; Calviño, F.; Calviani, M.; Carrapiço, C.; Cerutti, F.; Chiaveri, E.; Chin, M.; Colonna, N.; Cortés, G.; Cortés-Giraldo, M. A.; Diakaki, M.; Dillmann, I.; Domingo-Pardo, C.; Durán, I.; Dzysiuk, N.; Eleftheriadis, C.; Fernández-Ordóñez, M.; Ferrari, A.; Fraval, K.; Furman, V.; Gómez-Hornillos, M. B.; Ganesan, S.; García, A. R.; Giubrone, G.; Gonçalves, I. F.; González, E.; Goverdovski, A.; Gramegna, F.; Griesmayer, E.; Guerrero, C.; Gunsing, F.; Gurusamy, P.; Heftrich, T.; Heinitz, S.; Hernández-Prieto, A.; Heyse, J.; Jenkins, D. G.; Jericha, E.; Käppeler, F.; Kadi, Y.; Karadimos, D.; Katabuchi, T.; Ketlerov, V.; Khryachkov, V.; Koehler, P.; Kokkoris, M.; Kroll, J.; Krtička, M.; Lampoudis, C.; Langer, C.; Leal-Cidoncha, E.; Lederer, C.; Leeb, H.; Leong, L. S.; Lerendegui-Marco, J.; Licata, M.; Losito, R.; Manousos, A.; Marganiec, J.; Martínez, T.; Massimi, C.; Mastinu, P.; Mastromarco, M.; Mengoni, A.; Milazzo, P. M.; Mingrone, F.; Mirea, M.; Mondelaers, W.; Paradela, C.; Pavlik, A.; Perkowski, J.; Plompen, A. J. M.; Praena, J.; Quesada, J. M.; Rauscher, T.; Reifarth, R.; Riego-Perez, A.; Robles, M.; Roman, F.; Rubbia, C.; Ryan, J. A.; Sabaté-Gilarte, M.; Sarmento, R.; Saxena, A.; Schillebeeckx, P.; Schmidt, S.; Schumann, D.; Sedyshev, P.; Tagliente, G.; Tain, J. L.; Tarifeño-Saldivia, A.; Tarrío, D.; Tassan-Got, L.; Tsinganis, A.; Valenta, S.; Vannini, G.; Variale, V.; Vaz, P.; Ventura, A.; Vermeulen, M. J.; Versaci, R.; Vlachoudis, V.; Vlastou, R.; Wallner, A.; Ware, T.; Weigand, M.; Weiss, C.; Wright, T.; Žugec, P.

2017-09-01

New neutron cross section measurements of minor actinides have been performed recently in order to reduce the uncertainties in the evaluated data, which is important for the design of advanced nuclear reactors and, in particular, for determining their performance in the transmutation of nuclear waste. We have measured the 241Am(n,γ) cross section at the n_TOF facility between 0.2 eV and 10 keV with a BaF2 Total Absorption Calorimeter, and the analysis of the measurement has been recently concluded. Our results are in reasonable agreement below 20 eV with the ones published by C. Lampoudis et al. in 2013, who reported a 22% larger capture cross section up to 110 eV compared to experimental and evaluated data published before. Our results also indicate that the 241Am(n,γ) cross section is underestimated in the present evaluated libraries between 20 eV and 2 keV by 25%, on average, and up to 35% for certain evaluations and energy ranges.

Virtual machine provisioning, code management, and data movement design for the Fermilab HEPCloud Facility

NASA Astrophysics Data System (ADS)

Timm, S.; Cooper, G.; Fuess, S.; Garzoglio, G.; Holzman, B.; Kennedy, R.; Grassano, D.; Tiradani, A.; Krishnamurthy, R.; Vinayagam, S.; Raicu, I.; Wu, H.; Ren, S.; Noh, S.-Y.

2017-10-01

The Fermilab HEPCloud Facility Project has as its goal to extend the current Fermilab facility interface to provide transparent access to disparate resources including commercial and community clouds, grid federations, and HPC centers. This facility enables experiments to perform the full spectrum of computing tasks, including data-intensive simulation and reconstruction. We have evaluated the use of the commercial cloud to provide elasticity to respond to peaks of demand without overprovisioning local resources. Full scale data-intensive workflows have been successfully completed on Amazon Web Services for two High Energy Physics Experiments, CMS and NOνA, at the scale of 58000 simultaneous cores. This paper describes the significant improvements that were made to the virtual machine provisioning system, code caching system, and data movement system to accomplish this work. The virtual image provisioning and contextualization service was extended to multiple AWS regions, and to support experiment-specific data configurations. A prototype Decision Engine was written to determine the optimal availability zone and instance type to run on, minimizing cost and job interruptions. We have deployed a scalable on-demand caching service to deliver code and database information to jobs running on the commercial cloud. It uses the frontiersquid server and CERN VM File System (CVMFS) clients on EC2 instances and utilizes various services provided by AWS to build the infrastructure (stack). We discuss the architecture and load testing benchmarks on the squid servers. We also describe various approaches that were evaluated to transport experimental data to and from the cloud, and the optimal solutions that were used for the bulk of the data transport. Finally, we summarize lessons learned from this scale test, and our future plans to expand and improve the Fermilab HEP Cloud Facility.

Virtual Machine Provisioning, Code Management, and Data Movement Design for the Fermilab HEPCloud Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Timm, S.; Cooper, G.; Fuess, S.

The Fermilab HEPCloud Facility Project has as its goal to extend the current Fermilab facility interface to provide transparent access to disparate resources including commercial and community clouds, grid federations, and HPC centers. This facility enables experiments to perform the full spectrum of computing tasks, including data-intensive simulation and reconstruction. We have evaluated the use of the commercial cloud to provide elasticity to respond to peaks of demand without overprovisioning local resources. Full scale data-intensive workflows have been successfully completed on Amazon Web Services for two High Energy Physics Experiments, CMS and NOνA, at the scale of 58000 simultaneous cores.more » This paper describes the significant improvements that were made to the virtual machine provisioning system, code caching system, and data movement system to accomplish this work. The virtual image provisioning and contextualization service was extended to multiple AWS regions, and to support experiment-specific data configurations. A prototype Decision Engine was written to determine the optimal availability zone and instance type to run on, minimizing cost and job interruptions. We have deployed a scalable on-demand caching service to deliver code and database information to jobs running on the commercial cloud. It uses the frontiersquid server and CERN VM File System (CVMFS) clients on EC2 instances and utilizes various services provided by AWS to build the infrastructure (stack). We discuss the architecture and load testing benchmarks on the squid servers. We also describe various approaches that were evaluated to transport experimental data to and from the cloud, and the optimal solutions that were used for the bulk of the data transport. Finally, we summarize lessons learned from this scale test, and our future plans to expand and improve the Fermilab HEP Cloud Facility.« less

The Cosmological Lithium Problem and the Measurement of the 7Be(n, α) Reaction at n_TOF-CERN

NASA Astrophysics Data System (ADS)

Musumarra, Agatino; Barbagallo, Massimo

A possible explanation of the so-called "Cosmological Lithium Problem", an important unsolved problem in Nuclear Astrophysics, involves large systematic uncertainties in the cross-sections of reactions leading to the destruction of 7Be during the Big-Bang Nucleosynthesis (BBN). Among these reactions, the 7Be(n, α) is the most uncertain. So far, only a single measurement with thermal neutrons has been performed. Therefore, BBN calculations had to rely on rather uncertain theoretical extrapolations. The short half-life of 7Be (53.29 d) and the low cross section have prevented, up to now, to obtain experimental data at keV neutron energies typical for BBN studies. We have measured for the first time at n_TOF the 7Be(n, α) reaction in a wide neutron energy range, from thermal up to 10 keV. This measurement has been performed, at the new beam line (EAR2) of the Neutron-Time-Of-Flight facility n_TOF at CERN. The two α-particles, emitted back-to-back in the reaction, have been detected by mean of sandwiches of silicon detectors and, by exploiting the coincidence technique, we were able to suppress the large γ and n-induced background. The 7Be isotope production and purification has been performed by PSI-Zurich Switzerland.

High duty factor plasma generator for CERN's Superconducting Proton Linac.

PubMed

Lettry, J; Kronberger, M; Scrivens, R; Chaudet, E; Faircloth, D; Favre, G; Geisser, J-M; Küchler, D; Mathot, S; Midttun, O; Paoluzzi, M; Schmitzer, C; Steyaert, D

2010-02-01

CERN's Linac4 is a 160 MeV linear accelerator currently under construction. It will inject negatively charged hydrogen ions into CERN's PS-Booster. Its ion source is a noncesiated rf driven H(-) volume source directly inspired from the one of DESY and is aimed to deliver pulses of 80 mA of H(-) during 0.4 ms at a 2 Hz repetition rate. The Superconducting Proton Linac (SPL) project is part of the luminosity upgrade of the Large Hadron Collider. It consists of an extension of Linac4 up to 5 GeV and is foreseen to deliver protons to a future 50 GeV synchrotron (PS2). For the SPL high power option (HP-SPL), the ion source would deliver pulses of 80 mA of H(-) during 1.2 ms and operate at a 50 Hz repetition rate. This significant upgrade motivates the design of the new water cooled plasma generator presented in this paper. Its engineering is based on the results of a finite element thermal study of the Linac4 H(-) plasma generator that identified critical components and thermal barriers. A cooling system is proposed which achieves the required heat dissipation and maintains the original functionality. Materials with higher thermal conductivity are selected and, wherever possible, thermal barriers resulting from low pressure contacts are removed by brazing metals on insulators. The AlN plasma chamber cooling circuit is inspired from the approach chosen for the cesiated high duty factor rf H(-) source operating at SNS.

Tape SCSI monitoring and encryption at CERN

NASA Astrophysics Data System (ADS)

Laskaridis, Stefanos; Bahyl, V.; Cano, E.; Leduc, J.; Murray, S.; Cancio, G.; Kruse, D.

2017-10-01

CERN currently manages the largest data archive in the HEP domain; over 180PB of custodial data is archived across 7 enterprise tape libraries containing more than 25,000 tapes and using over 100 tape drives. Archival storage at this scale requires a leading edge monitoring infrastructure that acquires live and lifelong metrics from the hardware in order to assess and proactively identify potential drive and media level issues. In addition, protecting the privacy of sensitive archival data is becoming increasingly important and with it the need for a scalable, compute-efficient and cost-effective solution for data encryption. In this paper, we first describe the implementation of acquiring tape medium and drive related metrics reported by the SCSI interface and its integration with our monitoring system. We then address the incorporation of tape drive real-time encryption with dedicated drive hardware into the CASTOR [1] hierarchical mass storage system.

Novel apparatus and methods for performing remotely controlled particle-solid interaction experiments at CERN

NASA Astrophysics Data System (ADS)

Krause, H. F.; Deveney, E. F.; Jones, N. L.; Vane, C. R.; Datz, S.; Knudsen, H.; Grafström, P.; Schuch, R.

1997-04-01

Recent atomic physics studies involving ultrarelativistic Pb ions required solid target positioners, scintillators, and a sophisticated data acquisition and control system placed in a remote location at the CERN Super Proton Synchrotron near Geneva, Switzerland. The apparatus, installed in a high-radiation zone underground, had to (i) function for months, (ii) automatically respond to failures such as power outages and particle-induced computer upsets, and (iii) communicate with the outside world via a telephone line. The heart of the apparatus developed was an Apple Macintosh-based CAMAC system that answered the telephone and interpreted and executed remote control commands that (i) sensed and set targets, (ii) controlled voltages and discriminator levels for scintillators, (iii) modified data acquisition hardware logic, (iv) reported control information, and (v) automatically synchronized data acquisition to the CERN spill cycle via a modem signal and transmitted experimental data to a remote computer. No problems were experienced using intercontinental telephone connections at 1200 baud. Our successful "virtual laboratory" approach that uses off-the-shelf electronics is generally adaptable to more conventional bench-type experiments.

Chicago Ebola Response Network (CERN): A Citywide Cross-hospital Collaborative for Infectious Disease Preparedness.

PubMed

Lateef, Omar; Hota, Bala; Landon, Emily; Kociolek, Larry K; Morita, Julie; Black, Stephanie; Noskin, Gary; Kelleher, Michael; Curell, Krista; Galat, Amy; Ansell, David; Segreti, John; Weber, Stephen G

2015-11-15

The 2014-2015 Ebola virus disease (EVD) epidemic and international public health emergency has been referred to as a "black swan" event, or an event that is unlikely, hard to predict, and highly impactful once it occurs. The Chicago Ebola Response Network (CERN) was formed in response to EVD and is capable of receiving and managing new cases of EVD, while also laying the foundation for a public health network that can anticipate, manage, and prevent the next black swan public health event. By sharing expertise, risk, and resources among 4 major academic centers, Chicago created a sustainable network to respond to the latest in a series of public health emergencies. In this respect, CERN is a roadmap for how a region can prepare to respond to public health emergencies, thereby preventing negative impacts through planning and implementation. © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Downgrading Nuclear Facilities to Radiological Facilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jarry, Jeffrey F.; Farr, Jesse Oscar; Duran, Leroy

2015-08-01

Based on inventory reductions and the use of alternate storage facilities, the Sandia National Laboratories (SNL) downgraded 4 SNL Hazard Category 3 (HC-3) nuclear facilities to less-than-HC-3 radiological facilities. SNL’s Waste Management and Pollution Prevention Department (WMPPD) managed the HC-3 nuclear facilities and implemented the downgrade. This paper will examine the downgrade process,

Uranium and Thorium

ERIC Educational Resources Information Center

Finch, Warren I.

1978-01-01

The results of President Carter's policy on non-proliferation of nuclear weapons are expected to slow the growth rate in energy consumption, put the development of the breeder reactor in question, halt plans to reprocess and recycle uranium and plutonium, and expand facilities to supply enriched uranium. (Author/MA)

Comparison of electromagnetic and hadronic models generated using Geant 4 with antiproton dose measured in CERN.

PubMed

Tavakoli, Mohammad Bagher; Reiazi, Reza; Mohammadi, Mohammad Mehdi; Jabbari, Keyvan

2015-01-01

After proposing the idea of antiproton cancer treatment in 1984 many experiments were launched to investigate different aspects of physical and radiobiological properties of antiproton, which came from its annihilation reactions. One of these experiments has been done at the European Organization for Nuclear Research known as CERN using the antiproton decelerator. The ultimate goal of this experiment was to assess the dosimetric and radiobiological properties of beams of antiprotons in order to estimate the suitability of antiprotons for radiotherapy. One difficulty on this way was the unavailability of antiproton beam in CERN for a long time, so the verification of Monte Carlo codes to simulate antiproton depth dose could be useful. Among available simulation codes, Geant4 provides acceptable flexibility and extensibility, which progressively lead to the development of novel Geant4 applications in research domains, especially modeling the biological effects of ionizing radiation at the sub-cellular scale. In this study, the depth dose corresponding to CERN antiproton beam energy by Geant4 recruiting all the standard physics lists currently available and benchmarked for other use cases were calculated. Overall, none of the standard physics lists was able to draw the antiproton percentage depth dose. Although, with some models our results were promising, the Bragg peak level remained as the point of concern for our study. It is concluded that the Bertini model with high precision neutron tracking (QGSP_BERT_HP) is the best to match the experimental data though it is also the slowest model to simulate events among the physics lists.

Monitoring tools of COMPASS experiment at CERN

NASA Astrophysics Data System (ADS)

Bodlak, M.; Frolov, V.; Huber, S.; Jary, V.; Konorov, I.; Levit, D.; Novy, J.; Salac, R.; Tomsa, J.; Virius, M.

2015-12-01

This paper briefly introduces the data acquisition system of the COMPASS experiment and is mainly focused on the part that is responsible for the monitoring of the nodes in the whole newly developed data acquisition system of this experiment. The COMPASS is a high energy particle experiment with a fixed target located at the SPS of the CERN laboratory in Geneva, Switzerland. The hardware of the data acquisition system has been upgraded to use FPGA cards that are responsible for data multiplexing and event building. The software counterpart of the system includes several processes deployed in heterogenous network environment. There are two processes, namely Message Logger and Message Browser, taking care of monitoring. These tools handle messages generated by nodes in the system. While Message Logger collects and saves messages to the database, the Message Browser serves as a graphical interface over the database containing these messages. For better performance, certain database optimizations have been used. Lastly, results of performance tests are presented.

The CMS experiment at the CERN LHC

NASA Astrophysics Data System (ADS)

CMS Collaboration; Chatrchyan, S.; Hmayakyan, G.; Khachatryan, V.; Sirunyan, A. M.; Adam, W.; Bauer, T.; Bergauer, T.; Bergauer, H.; Dragicevic, M.; Erö, J.; Friedl, M.; Frühwirth, R.; Ghete, V. M.; Glaser, P.; Hartl, C.; Hoermann, N.; Hrubec, J.; Hänsel, S.; Jeitler, M.; Kastner, K.; Krammer, M.; Magrans de Abril, I.; Markytan, M.; Mikulec, I.; Neuherz, B.; Nöbauer, T.; Oberegger, M.; Padrta, M.; Pernicka, M.; Porth, P.; Rohringer, H.; Schmid, S.; Schreiner, T.; Stark, R.; Steininger, H.; Strauss, J.; Taurok, A.; Uhl, D.; Waltenberger, W.; Walzel, G.; Widl, E.; Wulz, C.-E.; Petrov, V.; Prosolovich, V.; Chekhovsky, V.; Dvornikov, O.; Emeliantchik, I.; Litomin, A.; Makarenko, V.; Marfin, I.; Mossolov, V.; Shumeiko, N.; Solin, A.; Stefanovitch, R.; Suarez Gonzalez, J.; Tikhonov, A.; Fedorov, A.; Korzhik, M.; Missevitch, O.; Zuyeuski, R.; Beaumont, W.; Cardaci, M.; DeLanghe, E.; DeWolf, E. A.; Delmeire, E.; Ochesanu, S.; Tasevsky, M.; Van Mechelen, P.; D'Hondt, J.; DeWeirdt, S.; Devroede, O.; Goorens, R.; Hannaert, S.; Heyninck, J.; Maes, J.; Mozer, M. U.; Tavernier, S.; Van Doninck, W.; Van Lancker, L.; Van Mulders, P.; Villella, I.; Wastiels, C.; Yu, C.; Bouhali, O.; Charaf, O.; Clerbaux, B.; DeHarenne, P.; DeLentdecker, G.; Dewulf, J. P.; Elgammal, S.; Gindroz, R.; Hammad, G. H.; Mahmoud, T.; Neukermans, L.; Pins, M.; Pins, R.; Rugovac, S.; Stefanescu, J.; Sundararajan, V.; Vander Velde, C.; Vanlaer, P.; Wickens, J.; Tytgat, M.; Assouak, S.; Bonnet, J. L.; Bruno, G.; Caudron, J.; DeCallatay, B.; DeFavereau DeJeneret, J.; DeVisscher, S.; Demin, P.; Favart, D.; Felix, C.; Florins, B.; Forton, E.; Giammanco, A.; Grégoire, G.; Jonckman, M.; Kcira, D.; Keutgen, T.; Lemaitre, V.; Michotte, D.; Militaru, O.; Ovyn, S.; Pierzchala, T.; Piotrzkowski, K.; Roberfroid, V.; Rouby, X.; Schul, N.; Van der Aa, O.; Beliy, N.; Daubie, E.; Herquet, P.; Alves, G.; Pol, M. E.; Souza, M. H. G.; Vaz, M.; DeJesus Damiao, D.; Oguri, V.; Santoro, A.; Sznajder, A.; DeMoraes Gregores, E.; Iope, R. L.; Novaes, S. F.; Tomei, T.; Anguelov, T.; Antchev, G.; Atanasov, I.; Damgov, J.; Darmenov, N.; Dimitrov, L.; Genchev, V.; Iaydjiev, P.; Marinov, A.; Piperov, S.; Stoykova, S.; Sultanov, G.; Trayanov, R.; Vankov, I.; Cheshkov, C.; Dimitrov, A.; Dyulendarova, M.; Glushkov, I.; Kozhuharov, V.; Litov, L.; Makariev, M.; Marinova, E.; Markov, S.; Mateev, M.; Nasteva, I.; Pavlov, B.; Petev, P.; Petkov, P.; Spassov, V.; Toteva, Z.; Velev, V.; Verguilov, V.; Bian, J. G.; Chen, G. M.; Chen, H. S.; Chen, M.; Jiang, C. H.; Liu, B.; Shen, X. Y.; Sun, H. S.; Tao, J.; Wang, J.; Yang, M.; Zhang, Z.; Zhao, W. R.; Zhuang, H. L.; Ban, Y.; Cai, J.; Ge, Y. C.; Liu, S.; Liu, H. T.; Liu, L.; Qian, S. J.; Wang, Q.; Xue, Z. H.; Yang, Z. C.; Ye, Y. L.; Ying, J.; Li, P. J.; Liao, J.; Xue, Z. L.; Yan, D. S.; Yuan, H.; Carrillo Montoya, C. A.; Sanabria, J. C.; Godinovic, N.; Puljak, I.; Soric, I.; Antunovic, Z.; Dzelalija, M.; Marasovic, K.; Brigljevic, V.; Kadija, K.; Morovic, S.; Fereos, R.; Nicolaou, C.; Papadakis, A.; Ptochos, F.; Razis, P. A.; Tsiakkouri, D.; Zinonos, Z.; Hektor, A.; Kadastik, M.; Kannike, K.; Lippmaa, E.; Müntel, M.; Raidal, M.; Rebane, L.; Aarnio, P. A.; Anttila, E.; Banzuzi, K.; Bulteau, P.; Czellar, S.; Eiden, N.; Eklund, C.; Engstrom, P.; Heikkinen, A.; Honkanen, A.; Härkönen, J.; Karimäki, V.; Katajisto, H. M.; Kinnunen, R.; Klem, J.; Kortesmaa, J.; Kotamäki, M.; Kuronen, A.; Lampén, T.; Lassila-Perini, K.; Lefébure, V.; Lehti, S.; Lindén, T.; Luukka, P. R.; Michal, S.; Moura Brigido, F.; Mäenpää, T.; Nyman, T.; Nystén, J.; Pietarinen, E.; Skog, K.; Tammi, K.; Tuominen, E.; Tuominiemi, J.; Ungaro, D.; Vanhala, T. P.; Wendland, L.; Williams, C.; Iskanius, M.; Korpela, A.; Polese, G.; Tuuva, T.; Bassompierre, G.; Bazan, A.; David, P. Y.; Ditta, J.; Drobychev, G.; Fouque, N.; Guillaud, J. P.; Hermel, V.; Karneyeu, A.; LeFlour, T.; Lieunard, S.; Maire, M.; Mendiburu, P.; Nedelec, P.; Peigneux, J. P.; Schneegans, M.; Sillou, D.; Vialle, J. P.; Anfreville, M.; Bard, J. P.; Besson, P.; Bougamont, E.; Boyer, M.; Bredy, P.; Chipaux, R.; Dejardin, M.; Denegri, D.; Descamps, J.; Fabbro, B.; Faure, J. L.; Ganjour, S.; Gentit, F. X.; Givernaud, A.; Gras, P.; Hamel de Monchenault, G.; Jarry, P.; Jeanney, C.; Kircher, F.; Lemaire, M. C.; Lemoigne, Y.; Levesy, B.; Locci, E.; Lottin, J. P.; Mandjavidze, I.; Mur, M.; Pansart, J. P.; Payn, A.; Rander, J.; Reymond, J. M.; Rolquin, J.; Rondeaux, F.; Rosowsky, A.; Rousse, J. Y. A.; Sun, Z. H.; Tartas, J.; Van Lysebetten, A.; Venault, P.; Verrecchia, P.; Anduze, M.; Badier, J.; Baffioni, S.; Bercher, M.; Bernet, C.; Berthon, U.; Bourotte, J.; Busata, A.; Busson, P.; Cerutti, M.; Chamont, D.; Charlot, C.; Collard, C.; Debraine, A.; Decotigny, D.; Dobrzynski, L.; Ferreira, O.; Geerebaert, Y.; Gilly, J.; Gregory, C.; Guevara Riveros, L.; Haguenauer, M.; Karar, A.; Koblitz, B.; Lecouturier, D.; Mathieu, A.; Milleret, G.; Miné, P.; Paganini, P.; Poilleux, P.; Pukhaeva, N.; Regnault, N.; Romanteau, T.; Semeniouk, I.; Sirois, Y.; Thiebaux, C.; Vanel, J. C.; Zabi, A.; Agram, J. L.; Albert, A.; Anckenmann, L.; Andrea, J.; Anstotz, F.; Bergdolt, A. M.; Berst, J. D.; Blaes, R.; Bloch, D.; Brom, J. M.; Cailleret, J.; Charles, F.; Christophel, E.; Claus, G.; Coffin, J.; Colledani, C.; Croix, J.; Dangelser, E.; Dick, N.; Didierjean, F.; Drouhin, F.; Dulinski, W.; Ernenwein, J. P.; Fang, R.; Fontaine, J. C.; Gaudiot, G.; Geist, W.; Gelé, D.; Goeltzenlichter, T.; Goerlach, U.; Graehling, P.; Gross, L.; Hu, C. Guo; Helleboid, J. M.; Henkes, T.; Hoffer, M.; Hoffmann, C.; Hosselet, J.; Houchu, L.; Hu, Y.; Huss, D.; Illinger, C.; Jeanneau, F.; Juillot, P.; Kachelhoffer, T.; Kapp, M. R.; Kettunen, H.; Lakehal Ayat, L.; LeBihan, A. C.; Lounis, A.; Maazouzi, C.; Mack, V.; Majewski, P.; Mangeol, D.; Michel, J.; Moreau, S.; Olivetto, C.; Pallarès, A.; Patois, Y.; Pralavorio, P.; Racca, C.; Riahi, Y.; Ripp-Baudot, I.; Schmitt, P.; Schunck, J. P.; Schuster, G.; Schwaller, B.; Sigward, M. H.; Sohler, J. L.; Speck, J.; Strub, R.; Todorov, T.; Turchetta, R.; Van Hove, P.; Vintache, D.; Zghiche, A.; Ageron, M.; Augustin, J. E.; Baty, C.; Baulieu, G.; Bedjidian, M.; Blaha, J.; Bonnevaux, A.; Boudoul, G.; Brunet, P.; Chabanat, E.; Chabert, E. C.; Chierici, R.; Chorowicz, V.; Combaret, C.; Contardo, D.; Della Negra, R.; Depasse, P.; Drapier, O.; Dupanloup, M.; Dupasquier, T.; El Mamouni, H.; Estre, N.; Fay, J.; Gascon, S.; Giraud, N.; Girerd, C.; Guillot, G.; Haroutunian, R.; Ille, B.; Lethuillier, M.; Lumb, N.; Martin, C.; Mathez, H.; Maurelli, G.; Muanza, S.; Pangaud, P.; Perries, S.; Ravat, O.; Schibler, E.; Schirra, F.; Smadja, G.; Tissot, S.; Trocme, B.; Vanzetto, S.; Walder, J. P.; Bagaturia, Y.; Mjavia, D.; Mzhavia, A.; Tsamalaidze, Z.; Roinishvili, V.; Adolphi, R.; Anagnostou, G.; Brauer, R.; Braunschweig, W.; Esser, H.; Feld, L.; Karpinski, W.; Khomich, A.; Klein, K.; Kukulies, C.; Lübelsmeyer, K.; Olzem, J.; Ostaptchouk, A.; Pandoulas, D.; Pierschel, G.; Raupach, F.; Schael, S.; Schultz von Dratzig, A.; Schwering, G.; Siedling, R.; Thomas, M.; Weber, M.; Wittmer, B.; Wlochal, M.; Adamczyk, F.; Adolf, A.; Altenhöfer, G.; Bechstein, S.; Bethke, S.; Biallass, P.; Biebel, O.; Bontenackels, M.; Bosseler, K.; Böhm, A.; Erdmann, M.; Faissner, H.; Fehr, B.; Fesefeldt, H.; Fetchenhauer, G.; Frangenheim, J.; Frohn, J. H.; Grooten, J.; Hebbeker, T.; Hermann, S.; Hermens, E.; Hilgers, G.; Hoepfner, K.; Hof, C.; Jacobi, E.; Kappler, S.; Kirsch, M.; Kreuzer, P.; Kupper, R.; Lampe, H. R.; Lanske, D.; Mameghani, R.; Meyer, A.; Meyer, S.; Moers, T.; Müller, E.; Pahlke, R.; Philipps, B.; Rein, D.; Reithler, H.; Reuter, W.; Rütten, P.; Schulz, S.; Schwarthoff, H.; Sobek, W.; Sowa, M.; Stapelberg, T.; Szczesny, H.; Teykal, H.; Teyssier, D.; Tomme, H.; Tomme, W.; Tonutti, M.; Tsigenov, O.; Tutas, J.; Vandenhirtz, J.; Wagner, H.; Wegner, M.; Zeidler, C.; Beissel, F.; Davids, M.; Duda, M.; Flügge, G.; Giffels, M.; Hermanns, T.; Heydhausen, D.; Kalinin, S.; Kasselmann, S.; Kaussen, G.; Kress, T.; Linn, A.; Nowack, A.; Perchalla, L.; Poettgens, M.; Pooth, O.; Sauerland, P.; Stahl, A.; Tornier, D.; Zoeller, M. H.; Behrens, U.; Borras, K.; Flossdorf, A.; Hatton, D.; Hegner, B.; Kasemann, M.; Mankel, R.; Meyer, A.; Mnich, J.; Rosemann, C.; Youngman, C.; Zeuner, W. D.; Bechtel, F.; Buhmann, P.; Butz, E.; Flucke, G.; Hamdorf, R. H.; Holm, U.; Klanner, R.; Pein, U.; Schirm, N.; Schleper, P.; Steinbrück, G.; Van Staa, R.; Wolf, R.; Atz, B.; Barvich, T.; Blüm, P.; Boegelspacher, F.; Bol, H.; Chen, Z. Y.; Chowdhury, S.; DeBoer, W.; Dehm, P.; Dirkes, G.; Fahrer, M.; Felzmann, U.; Frey, M.; Furgeri, A.; Gregoriev, E.; Hartmann, F.; Hauler, F.; Heier, S.; Kärcher, K.; Ledermann, B.; Mueller, S.; Müller, Th; Neuberger, D.; Piasecki, C.; Quast, G.; Rabbertz, K.; Sabellek, A.; Scheurer, A.; Schilling, F. P.; Simonis, H. J.; Skiba, A.; Steck, P.; Theel, A.; Thümmel, W. H.; Trunov, A.; Vest, A.; Weiler, T.; Weiser, C.; Weseler, S.; Zhukov, V.; Barone, M.; Daskalakis, G.; Dimitriou, N.; Fanourakis, G.; Filippidis, C.; Geralis, T.; Kalfas, C.; Karafasoulis, K.; Koimas, A.; Kyriakis, A.; Kyriazopoulou, S.; Loukas, D.; Markou, A.; Markou, C.; Mastroyiannopoulos, N.; Mavrommatis, C.; Mousa, J.; Papadakis, I.; Petrakou, E.; Siotis, I.; Theofilatos, K.; Tzamarias, S.; Vayaki, A.; Vermisoglou, G.; Zachariadou, A.; Gouskos, L.; Karapostoli, G.; Katsas, P.; Panagiotou, A.; Papadimitropoulos, C.; Aslanoglou, X.; Evangelou, I.; Kokkas, P.; Manthos, N.; Papadopoulos, I.; Triantis, F. A.; Bencze, G.; Boldizsar, L.; Debreczeni, G.; Hajdu, C.; Hidas, P.; Horvath, D.; Kovesarki, P.; Laszlo, A.; Odor, G.; Patay, G.; Sikler, F.; Veres, G.; Vesztergombi, G.; Zalan, P.; Fenyvesi, A.; Imrek, J.; Molnar, J.; Novak, D.; Palinkas, J.; Szekely, G.; Beni, N.; Kapusi, A.; Marian, G.; Radics, B.; Raics, P.; Szabo, Z.; Szillasi, Z.; Trocsanyi, Z. L.; Zilizi, G.; Bawa, H. S.; Beri, S. B.; Bhandari, V.; Bhatnagar, V.; Kaur, M.; Kohli, J. M.; Kumar, A.; Singh, B.; Singh, J. B.; Arora, S.; Bhattacharya, S.; Chatterji, S.; Chauhan, S.; Choudhary, B. C.; Gupta, P.; Jha, M.; Ranjan, K.; Shivpuri, R. K.; Srivastava, A. K.; Choudhury, R. K.; Dutta, D.; Ghodgaonkar, M.; Kailas, S.; Kataria, S. K.; Mohanty, A. K.; Pant, L. M.; Shukla, P.; Topkar, A.; Aziz, T.; Banerjee, Sunanda; Bose, S.; Chendvankar, S.; Deshpande, P. V.; Guchait, M.; Gurtu, A.; Maity, M.; Majumder, G.; Mazumdar, K.; Nayak, A.; Patil, M. R.; Sharma, S.; Sudhakar, K.; Acharya, B. S.; Banerjee, Sudeshna; Bheesette, S.; Dugad, S.; Kalmani, S. D.; Lakkireddi, V. R.; Mondal, N. K.; Panyam, N.; Verma, P.; Arfaei, H.; Hashemi, M.; Najafabadi, M. Mohammadi; Moshaii, A.; Paktinat Mehdiabadi, S.; Felcini, M.; Grunewald, M.; Abadjiev, K.; Abbrescia, M.; Barbone, L.; Cariola, P.; Chiumarulo, F.; Clemente, A.; Colaleo, A.; Creanza, D.; DeFilippis, N.; DePalma, M.; DeRobertis, G.; Donvito, G.; Ferorelli, R.; Fiore, L.; Franco, M.; Giordano, D.; Guida, R.; Iaselli, G.; Lacalamita, N.; Loddo, F.; Maggi, G.; Maggi, M.; Manna, N.; Marangelli, B.; Mennea, M. S.; My, S.; Natali, S.; Nuzzo, S.; Papagni, G.; Pinto, C.; Pompili, A.; Pugliese, G.; Ranieri, A.; Romano, F.; Roselli, G.; Sala, G.; Selvaggi, G.; Silvestris, L.; Tempesta, P.; Trentadue, R.; Tupputi, S.; Zito, G.; Abbiendi, G.; Bacchi, W.; Battilana, C.; Benvenuti, A. C.; Boldini, M.; Bonacorsi, D.; Braibant-Giacomelli, S.; Cafaro, V. D.; Capiluppi, P.; Castro, A.; Cavallo, F. R.; Ciocca, C.; Codispoti, G.; Cuffiani, M.; D'Antone, I.; Dallavalle, G. M.; Fabbri, F.; Fanfani, A.; Finelli, S.; Giacomelli, P.; Giordano, V.; Giunta, M.; Grandi, C.; Guerzoni, M.; Guiducci, L.; Marcellini, S.; Masetti, G.; Montanari, A.; Navarria, F. L.; Odorici, F.; Paolucci, A.; Pellegrini, G.; Perrotta, A.; Rossi, A. M.; Rovelli, T.; Siroli, G. P.; Torromeo, G.; Travaglini, R.; Veronese, G. P.; Albergo, S.; Chiorboli, M.; Costa, S.; Galanti, M.; Gatto Rotondo, G.; Giudice, N.; Guardone, N.; Noto, F.; Potenza, R.; Saizu, M. A.; Salemi, G.; Sutera, C.; Tricomi, A.; Tuve, C.; Bellucci, L.; Brianzi, M.; Broccolo, G.; Catacchini, E.; Ciulli, V.; Civinini, C.; D'Alessandro, R.; Focardi, E.; Frosali, S.; Genta, C.; Landi, G.; Lenzi, P.; Macchiolo, A.; Maletta, F.; Manolescu, F.; Marchettini, C.; Masetti, L.; Mersi, S.; Meschini, M.; Minelli, C.; Paoletti, S.; Parrini, G.; Scarlini, E.; Sguazzoni, G.; Benussi, L.; Bertani, M.; Bianco, S.; Caponero, M.; Colonna, D.; Daniello, L.; Fabbri, F.; Felli, F.; Giardoni, M.; La Monaca, A.; Ortenzi, B.; Pallotta, M.; Paolozzi, A.; Paris, C.; Passamonti, L.; Pierluigi, D.; Ponzio, B.; Pucci, C.; Russo, A.; Saviano, G.; Fabbricatore, P.; Farinon, S.; Greco, M.; Musenich, R.; Badoer, S.; Berti, L.; Biasotto, M.; Fantinel, S.; Frizziero, E.; Gastaldi, U.; Gulmini, M.; Lelli, F.; Maron, G.; Squizzato, S.; Toniolo, N.; Traldi, S.; Banfi, S.; Bertoni, R.; Bonesini, M.; Carbone, L.; Cerati, G. B.; Chignoli, F.; D'Angelo, P.; DeMin, A.; Dini, P.; Farina, F. M.; Ferri, F.; Govoni, P.; Magni, S.; Malberti, M.; Malvezzi, S.; Mazza, R.; Menasce, D.; Miccio, V.; Moroni, L.; Negri, P.; Paganoni, M.; Pedrini, D.; Pullia, A.; Ragazzi, S.; Redaelli, N.; Rovere, M.; Sala, L.; Sala, S.; Salerno, R.; Tabarelli de Fatis, T.; Tancini, V.; Taroni, S.; Boiano, A.; Cassese, F.; Cassese, C.; Cimmino, A.; D'Aquino, B.; Lista, L.; Lomidze, D.; Noli, P.; Paolucci, P.; Passeggio, G.; Piccolo, D.; Roscilli, L.; Sciacca, C.; Vanzanella, A.; Azzi, P.; Bacchetta, N.; Barcellan, L.; Bellato, M.; Benettoni, M.; Bisello, D.; Borsato, E.; Candelori, A.; Carlin, R.; Castellani, L.; Checchia, P.; Ciano, L.; Colombo, A.; Conti, E.; Da Rold, M.; Dal Corso, F.; DeGiorgi, M.; DeMattia, M.; Dorigo, T.; Dosselli, U.; Fanin, C.; Galet, G.; Gasparini, F.; Gasparini, U.; Giraldo, A.; Giubilato, P.; Gonella, F.; Gresele, A.; Griggio, A.; Guaita, P.; Kaminskiy, A.; Karaevskii, S.; Khomenkov, V.; Kostylev, D.; Lacaprara, S.; Lazzizzera, I.; Lippi, I.; Loreti, M.; Margoni, M.; Martinelli, R.; Mattiazzo, S.; Mazzucato, M.; Meneguzzo, A. T.; Modenese, L.; Montecassiano, F.; Neviani, A.; Nigro, M.; Paccagnella, A.; Pantano, D.; Parenti, A.; Passaseo, M.; Pedrotta, R.; Pegoraro, M.; Rampazzo, G.; Reznikov, S.; Ronchese, P.; Sancho Daponte, A.; Sartori, P.; Stavitskiy, I.; Tessaro, M.; Torassa, E.; Triossi, A.; Vanini, S.; Ventura, S.; Ventura, L.; Verlato, M.; Zago, M.; Zatti, F.; Zotto, P.; Zumerle, G.; Baesso, P.; Belli, G.; Berzano, U.; Bricola, S.; Grelli, A.; Musitelli, G.; Nardò, R.; Necchi, M. M.; Pagano, D.; Ratti, S. P.; Riccardi, C.; Torre, P.; Vicini, A.; Vitulo, P.; Viviani, C.; Aisa, D.; Aisa, S.; Ambroglini, F.; Angarano, M. M.; Babucci, E.; Benedetti, D.; Biasini, M.; Bilei, G. M.; Bizzaglia, S.; Brunetti, M. T.; Caponeri, B.; Checcucci, B.; Covarelli, R.; Dinu, N.; Fanò, L.; Farnesini, L.; Giorgi, M.; Lariccia, P.; Mantovani, G.; Moscatelli, F.; Passeri, D.; Piluso, A.; Placidi, P.; Postolache, V.; Santinelli, R.; Santocchia, A.; Servoli, L.; Spiga, D.; Azzurri, P.; Bagliesi, G.; Balestri, G.; Basti, A.; Bellazzini, R.; Benucci, L.; Bernardini, J.; Berretta, L.; Bianucci, S.; Boccali, T.; Bocci, A.; Borrello, L.; Bosi, F.; Bracci, F.; Brez, A.; Calzolari, F.; Castaldi, R.; Cazzola, U.; Ceccanti, M.; Cecchi, R.; Cerri, C.; Cucoanes, A. S.; Dell'Orso, R.; Dobur, D.; Dutta, S.; Fiori, F.; Foà, L.; Gaggelli, A.; Gennai, S.; Giassi, A.; Giusti, S.; Kartashov, D.; Kraan, A.; Latronico, L.; Ligabue, F.; Linari, S.; Lomtadze, T.; Lungu, G. A.; Magazzu, G.; Mammini, P.; Mariani, F.; Martinelli, G.; Massa, M.; Messineo, A.; Moggi, A.; Palla, F.; Palmonari, F.; Petragnani, G.; Petrucciani, G.; Profeti, A.; Raffaelli, F.; Rizzi, D.; Sanguinetti, G.; Sarkar, S.; Segneri, G.; Sentenac, D.; Serban, A. T.; Slav, A.; Spagnolo, P.; Spandre, G.; Tenchini, R.; Tolaini, S.; Tonelli, G.; Venturi, A.; Verdini, P. G.; Vos, M.; Zaccarelli, L.; Baccaro, S.; Barone, L.; Bartoloni, A.; Borgia, B.; Capradossi, G.; Cavallari, F.; Cecilia, A.; D'Angelo, D.; Dafinei, I.; DelRe, D.; Di Marco, E.; Diemoz, M.; Ferrara, G.; Gargiulo, C.; Guerra, S.; Iannone, M.; Longo, E.; Montecchi, M.; Nuccetelli, M.; Organtini, G.; Palma, A.; Paramatti, R.; Pellegrino, F.; Rahatlou, S.; Rovelli, C.; Safai Tehrani, F.; Zullo, A.; Alampi, G.; Amapane, N.; Arcidiacono, R.; Argiro, S.; Arneodo, M.; Bellan, R.; Benotto, F.; Biino, C.; Bolognesi, S.; Borgia, M. A.; Botta, C.; Brasolin, A.; Cartiglia, N.; Castello, R.; Cerminara, G.; Cirio, R.; Cordero, M.; Costa, M.; Dattola, D.; Daudo, F.; Dellacasa, G.; Demaria, N.; Dughera, G.; Dumitrache, F.; Farano, R.; Ferrero, G.; Filoni, E.; Kostyleva, G.; Larsen, H. E.; Mariotti, C.; Marone, M.; Maselli, S.; Menichetti, E.; Mereu, P.; Migliore, E.; Mila, G.; Monaco, V.; Musich, M.; Nervo, M.; Obertino, M. M.; Panero, R.; Parussa, A.; Pastrone, N.; Peroni, C.; Petrillo, G.; Romero, A.; Ruspa, M.; Sacchi, R.; Scalise, M.; Solano, A.; Staiano, A.; Trapani, P. P.; Trocino, D.; Vaniev, V.; Vilela Pereira, A.; Zampieri, A.; Belforte, S.; Cossutti, F.; Della Ricca, G.; Gobbo, B.; Kavka, C.; Penzo, A.; Kim, Y. E.; Nam, S. K.; Kim, D. H.; Kim, G. N.; Kim, J. C.; Kong, D. J.; Ro, S. R.; Son, D. C.; Park, S. Y.; Kim, Y. J.; Kim, J. Y.; Lim, I. T.; Pac, M. Y.; Lee, S. J.; Jung, S. Y.; Rhee, J. T.; Ahn, S. H.; Hong, B. S.; Jeng, Y. K.; Kang, M. H.; Kim, H. C.; Kim, J. H.; Kim, T. J.; Lee, K. S.; Lim, J. K.; Moon, D. H.; Park, I. C.; Park, S. K.; Ryu, M. S.; Sim, K.-S.; Son, K. J.; Hong, S. J.; Choi, Y. I.; Castilla Valdez, H.; Sanchez Hernandez, A.; Carrillo Moreno, S.; Morelos Pineda, A.; Aerts, A.; Van der Stok, P.; Weffers, H.; Allfrey, P.; Gray, R. N. C.; Hashimoto, M.; Krofcheck, D.; Bell, A. J.; Bernardino Rodrigues, N.; Butler, P. H.; Churchwell, S.; Knegjens, R.; Whitehead, S.; Williams, J. C.; Aftab, Z.; Ahmad, U.; Ahmed, I.; Ahmed, W.; Asghar, M. I.; Asghar, S.; Dad, G.; Hafeez, M.; Hoorani, H. R.; Hussain, I.; Hussain, N.; Iftikhar, M.; Khan, M. S.; Mehmood, K.; Osman, A.; Shahzad, H.; Zafar, A. R.; Ali, A.; Bashir, A.; Jan, A. M.; Kamal, A.; Khan, F.; Saeed, M.; Tanwir, S.; Zafar, M. A.; Blocki, J.; Cyz, A.; Gladysz-Dziadus, E.; Mikocki, S.; Rybczynski, M.; Turnau, J.; Wlodarczyk, Z.; Zychowski, P.; Bunkowski, K.; Cwiok, M.; Czyrkowski, H.; Dabrowski, R.; Dominik, W.; Doroba, K.; Kalinowski, A.; Kierzkowski, K.; Konecki, M.; Krolikowski, J.; Kudla, I. M.; Pietrusinski, M.; Pozniak, K.; Zabolotny, W.; Zych, P.; Gokieli, R.; Goscilo, L.; Górski, M.; Nawrocki, K.; Traczyk, P.; Wrochna, G.; Zalewski, P.; Pozniak, K. T.; Romaniuk, R.; Zabolotny, W. M.; Alemany-Fernandez, R.; Almeida, C.; Almeida, N.; Araujo Vila Verde, A. S.; Barata Monteiro, T.; Bluj, M.; Da Mota Silva, S.; Tinoco Mendes, A. David; Freitas Ferreira, M.; Gallinaro, M.; Husejko, M.; Jain, A.; Kazana, M.; Musella, P.; Nobrega, R.; Rasteiro Da Silva, J.; Ribeiro, P. Q.; Santos, M.; Silva, P.; Silva, S.; Teixeira, I.; Teixeira, J. P.; Varela, J.; Varner, G.; Vaz Cardoso, N.; Altsybeev, I.; Babich, K.; Belkov, A.; Belotelov, I.; Bunin, P.; Chesnevskaya, S.; Elsha, V.; Ershov, Y.; Filozova, I.; Finger, M.; Finger, M., Jr.; Golunov, A.; Golutvin, I.; Gorbounov, N.; Gramenitski, I.; Kalagin, V.; Kamenev, A.; Karjavin, V.; Khabarov, S.; Khabarov, V.; Kiryushin, Y.; Konoplyanikov, V.; Korenkov, V.; Kozlov, G.; Kurenkov, A.; Lanev, A.; Lysiakov, V.; Malakhov, A.; Melnitchenko, I.; Mitsyn, V. V.; Moisenz, K.; Moisenz, P.; Movchan, S.; Nikonov, E.; Oleynik, D.; Palichik, V.; Perelygin, V.; Petrosyan, A.; Rogalev, E.; Samsonov, V.; Savina, M.; Semenov, R.; Sergeev, S.; Shmatov, S.; Shulha, S.; Smirnov, V.; Smolin, D.; Tcheremoukhine, A.; Teryaev, O.; Tikhonenko, E.; Urkinbaev, A.; Vasil'ev, S.; Vishnevskiy, A.; Volodko, A.; Zamiatin, N.; Zarubin, A.; Zarubin, P.; Zubarev, E.; Bondar, N.; Gavrikov, Y.; Golovtsov, V.; Ivanov, Y.; Kim, V.; Kozlov, V.; Lebedev, V.; Makarenkov, G.; Moroz, F.; Neustroev, P.; Obrant, G.; Orishchin, E.; Petrunin, A.; Shcheglov, Y.; Shchetkovskiy, A.; Sknar, V.; Skorobogatov, V.; Smirnov, I.; Sulimov, V.; Tarakanov, V.; Uvarov, L.; Vavilov, S.; Velichko, G.; Volkov, S.; Vorobyev, A.; Chmelev, D.; Druzhkin, D.; Ivanov, A.; Kudinov, V.; Logatchev, O.; Onishchenko, S.; Orlov, A.; Sakharov, V.; Smetannikov, V.; Tikhomirov, A.; Zavodthikov, S.; Andreev, Yu; Anisimov, A.; Duk, V.; Gninenko, S.; Golubev, N.; Gorbunov, D.; Kirsanov, M.; Krasnikov, N.; Matveev, V.; Pashenkov, A.; Pastsyak, A.; Postoev, V. E.; Sadovski, A.; Skassyrskaia, A.; Solovey, Alexander; Solovey, Anatoly; Soloviev, D.; Toropin, A.; Troitsky, S.; Alekhin, A.; Baldov, A.; Epshteyn, V.; Gavrilov, V.; Ilina, N.; Kaftanov, V.; Karpishin, V.; Kiselevich, I.; Kolosov, V.; Kossov, M.; Krokhotin, A.; Kuleshov, S.; Oulianov, A.; Pozdnyakov, A.; Safronov, G.; Semenov, S.; Stepanov, N.; Stolin, V.; Vlasov, E.; Zaytsev, V.; Boos, E.; Dubinin, M.; Dudko, L.; Ershov, A.; Eyyubova, G.; Gribushin, A.; Ilyin, V.; Klyukhin, V.; Kodolova, O.; Kruglov, N. A.; Kryukov, A.; Lokhtin, I.; Malinina, L.; Mikhaylin, V.; Petrushanko, S.; Sarycheva, L.; Savrin, V.; Shamardin, L.; Sherstnev, A.; Snigirev, A.; Teplov, K.; Vardanyan, I.; Fomenko, A. M.; Konovalova, N.; Kozlov, V.; Lebedev, A. I.; Lvova, N.; Rusakov, S. V.; Terkulov, A.; Abramov, V.; Akimenko, S.; Artamonov, A.; Ashimova, A.; Azhgirey, I.; Bitioukov, S.; Chikilev, O.; Datsko, K.; Filine, A.; Godizov, A.; Goncharov, P.; Grishin, V.; Inyakin, A.; Kachanov, V.; Kalinin, A.; Khmelnikov, A.; Konstantinov, D.; Korablev, A.; Krychkine, V.; Krinitsyn, A.; Levine, A.; Lobov, I.; Lukanin, V.; Mel'nik, Y.; Molchanov, V.; Petrov, V.; Petukhov, V.; Pikalov, V.; Ryazanov, A.; Ryutin, R.; Shelikhov, V.; Skvortsov, V.; Slabospitsky, S.; Sobol, A.; Sytine, A.; Talov, V.; Tourtchanovitch, L.; Troshin, S.; Tyurin, N.; Uzunian, A.; Volkov, A.; Zelepoukine, S.; Lukyanov, V.; Mamaeva, G.; Prilutskaya, Z.; Rumyantsev, I.; Sokha, S.; Tataurschikov, S.; Vasilyev, I.; Adzic, P.; Anicin, I.; Djordjevic, M.; Jovanovic, D.; Maletic, D.; Puzovic, J.; Smiljkovic, N.; Aguayo Navarrete, E.; Aguilar-Benitez, M.; Ahijado Munoz, J.; Alarcon Vega, J. M.; Alberdi, J.; Alcaraz Maestre, J.; Aldaya Martin, M.; Arce, P.; Barcala, J. M.; Berdugo, J.; Blanco Ramos, C. L.; Burgos Lazaro, C.; Caballero Bejar, J.; Calvo, E.; Cerrada, M.; Chamizo Llatas, M.; Chercoles Catalán, J. J.; Colino, N.; Daniel, M.; DeLa Cruz, B.; Delgado Peris, A.; Fernandez Bedoya, C.; Ferrando, A.; Fouz, M. C.; Francia Ferrero, D.; Garcia Romero, J.; Garcia-Abia, P.; Gonzalez Lopez, O.; Hernandez, J. M.; Josa, M. I.; Marin, J.; Merino, G.; Molinero, A.; Navarrete, J. J.; Oller, J. C.; Puerta Pelayo, J.; Puras Sanchez, J. C.; Ramirez, J.; Romero, L.; Villanueva Munoz, C.; Willmott, C.; Yuste, C.; Albajar, C.; de Trocóniz, J. F.; Jimenez, I.; Macias, R.; Teixeira, R. F.; Cuevas, J.; Fernández Menéndez, J.; Gonzalez Caballero, I.; Lopez-Garcia, J.; Naves Sordo, H.; Vizan Garcia, J. M.; Cabrillo, I. J.; Calderon, A.; Cano Fernandez, D.; Diaz Merino, I.; Duarte Campderros, J.; Fernandez, M.; Fernandez Menendez, J.; Figueroa, C.; Garcia Moral, L. A.; Gomez, G.; Gomez Casademunt, F.; Gonzalez Sanchez, J.; Gonzalez Suarez, R.; Jorda, C.; Lobelle Pardo, P.; Lopez Garcia, A.; Lopez Virto, A.; Marco, J.; Marco, R.; Martinez Rivero, C.; Martinez Ruiz del Arbol, P.; Matorras, F.; Orviz Fernandez, P.; Patino Revuelta, A.; Rodrigo, T.; Rodriguez Gonzalez, D.; Ruiz Jimeno, A.; Scodellaro, L.; Sobron Sanudo, M.; Vila, I.; Vilar Cortabitarte, R.; Barbero, M.; Goldin, D.; Henrich, B.; Tauscher, L.; Vlachos, S.; Wadhwa, M.; Abbaneo, D.; Abbas, S. M.; Ahmed, I.; Akhtar, S.; Akhtar, M. I.; Albert, E.; Alidra, M.; Ashby, S.; Aspell, P.; Auffray, E.; Baillon, P.; Ball, A.; Bally, S. L.; Bangert, N.; Barillère, R.; Barney, D.; Beauceron, S.; Beaudette, F.; Benelli, G.; Benetta, R.; Benichou, J. L.; Bialas, W.; Bjorkebo, A.; Blechschmidt, D.; Bloch, C.; Bloch, P.; Bonacini, S.; Bos, J.; Bosteels, M.; Boyer, V.; Branson, A.; Breuker, H.; Bruneliere, R.; Buchmuller, O.; Campi, D.; Camporesi, T.; Caner, A.; Cano, E.; Carrone, E.; Cattai, A.; Chatelain, J. P.; Chauvey, M.; Christiansen, T.; Ciganek, M.; Cittolin, S.; Cogan, J.; Conde Garcia, A.; Cornet, H.; Corrin, E.; Corvo, M.; Cucciarelli, S.; Curé, B.; D'Enterria, D.; DeRoeck, A.; de Visser, T.; Delaere, C.; Delattre, M.; Deldicque, C.; Delikaris, D.; Deyrail, D.; Di Vincenzo, S.; Domeniconi, A.; Dos Santos, S.; Duthion, G.; Edera, L. M.; Elliott-Peisert, A.; Eppard, M.; Fanzago, F.; Favre, M.; Foeth, H.; Folch, R.; Frank, N.; Fratianni, S.; Freire, M. A.; Frey, A.; Fucci, A.; Funk, W.; Gaddi, A.; Gagliardi, F.; Gastal, M.; Gateau, M.; Gayde, J. C.; Gerwig, H.; Ghezzi, A.; Gigi, D.; Gill, K.; Giolo-Nicollerat, A. S.; Girod, J. P.; Glege, F.; Glessing, W.; Gomez-Reino Garrido, R.; Goudard, R.; Grabit, R.; Grillet, J. 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R.; Egeland, R.; Franzoni, G.; Gilbert, W. J.; Gong, D.; Grahl, J.; Haupt, J.; Klapoetke, K.; Kronkvist, I.; Kubota, Y.; Mans, J.; Rusack, R.; Sengupta, S.; Sherwood, B.; Singovsky, A.; Vikas, P.; Zhang, J.; Booke, M.; Cremaldi, L. M.; Godang, R.; Kroeger, R.; Reep, M.; Reidy, J.; Sanders, D. A.; Sonnek, P.; Summers, D.; Watkins, S.; Bloom, K.; Bockelman, B.; Claes, D. R.; Dominguez, A.; Eads, M.; Furukawa, M.; Keller, J.; Kelly, T.; Lundstedt, C.; Malik, S.; Snow, G. R.; Swanson, D.; Ecklund, K. M.; Iashvili, I.; Kharchilava, A.; Kumar, A.; Strang, M.; Alverson, G.; Barberis, E.; Boeriu, O.; Eulisse, G.; McCauley, T.; Musienko, Y.; Muzaffar, S.; Osborne, I.; Reucroft, S.; Swain, J.; Taylor, L.; Tuura, L.; Gobbi, B.; Kubantsev, M.; Kubik, A.; Ofierzynski, R. A.; Schmitt, M.; Spencer, E.; Stoynev, S.; Szleper, M.; Velasco, M.; Won, S.; Andert, K.; Baumbaugh, B.; Beiersdorf, B. A.; Castle, L.; Chorny, J.; Goussiou, A.; Hildreth, M.; Jessop, C.; Karmgard, D. J.; Kolberg, T.; Marchant, J.; Marinelli, N.; McKenna, M.; Ruchti, R.; Vigneault, M.; Wayne, M.; Wiand, D.; Bylsma, B.; Durkin, L. S.; Gilmore, J.; Gu, J.; Killewald, P.; Ling, T. Y.; Rush, C. J.; Sehgal, V.; Williams, G.; Adam, N.; Chidzik, S.; Denes, P.; Elmer, P.; Garmash, A.; Gerbaudo, D.; Halyo, V.; Jones, J.; Marlow, D.; Olsen, J.; Piroué, P.; Stickland, D.; Tully, C.; Werner, J. S.; Wildish, T.; Wynhoff, S.; Xie, Z.; Huang, X. T.; Lopez, A.; Mendez, H.; Ramirez Vargas, J. E.; Zatserklyaniy, A.; Apresyan, A.; Arndt, K.; Barnes, V. E.; Bolla, G.; Bortoletto, D.; Bujak, A.; Everett, A.; Fahling, M.; Garfinkel, A. F.; Gutay, L.; Ippolito, N.; Kozhevnikov, Y.; Laasanen, A. T.; Liu, C.; Maroussov, V.; Medved, S.; Merkel, P.; Miller, D. H.; Miyamoto, J.; Neumeister, N.; Pompos, A.; Roy, A.; Sedov, A.; Shipsey, I.; Cuplov, V.; Parashar, N.; Bargassa, P.; Lee, S. J.; Liu, J. H.; Maronde, D.; Matveev, M.; Nussbaum, T.; Padley, B. P.; Roberts, J.; Tumanov, A.; Bodek, A.; Budd, H.; Cammin, J.; Chung, Y. S.; DeBarbaro, P.; Demina, R.; Ginther, G.; Gotra, Y.; Korjenevski, S.; Miner, D. C.; Sakumoto, W.; Slattery, P.; Zielinski, M.; Bhatti, A.; Demortier, L.; Goulianos, K.; Hatakeyama, K.; Mesropian, C.; Bartz, E.; Chuang, S. H.; Doroshenko, J.; Halkiadakis, E.; Jacques, P. F.; Khits, D.; Lath, A.; Macpherson, A.; Plano, R.; Rose, K.; Schnetzer, S.; Somalwar, S.; Stone, R.; Watts, T. L.; Cerizza, G.; Hollingsworth, M.; Lazoflores, J.; Ragghianti, G.; Spanier, S.; York, A.; Aurisano, A.; Golyash, A.; Kamon, T.; Nguyen, C. N.; Pivarski, J.; Safonov, A.; Toback, D.; Weinberger, M.; Akchurin, N.; Berntzon, L.; Carrell, K. W.; Gumus, K.; Jeong, C.; Kim, H.; Lee, S. W.; McGonagill, B. G.; Roh, Y.; Sill, A.; Spezziga, M.; Thomas, R.; Volobouev, I.; Washington, E.; Wigmans, R.; Yazgan, E.; Bapty, T.; Engh, D.; Florez, C.; Johns, W.; Keskinpala, T.; Luiggi Lopez, E.; Neema, S.; Nordstrom, S.; Pathak, S.; Sheldon, P.; Andelin, D.; Arenton, M. W.; Balazs, M.; Buehler, M.; Conetti, S.; Cox, B.; Hirosky, R.; Humphrey, M.; Imlay, R.; Ledovskoy, A.; Phillips, D., II; Powell, H.; Ronquest, M.; Yohay, R.; Anderson, M.; Baek, Y. W.; Bellinger, J. N.; Bradley, D.; Cannarsa, P.; Carlsmith, D.; Crotty, I.; Dasu, S.; Feyzi, F.; Gorski, T.; Gray, L.; Grogg, K. S.; Grothe, M.; Jaworski, M.; Klabbers, P.; Klukas, J.; Lanaro, A.; Lazaridis, C.; Leonard, J.; Loveless, R.; Magrans de Abril, M.; Mohapatra, A.; Ott, G.; Smith, W. H.; Weinberg, M.; Wenman, D.; Atoian, G. S.; Dhawan, S.; Issakov, V.; Neal, H.; Poblaguev, A.; Zeller, M. E.; Abdullaeva, G.; Avezov, A.; Fazylov, M. I.; Gasanov, E. M.; Khugaev, A.; Koblik, Y. N.; Nishonov, M.; Olimov, K.; Umaraliev, A.; Yuldashev, B. S.

2008-08-01

The Compact Muon Solenoid (CMS) detector is described. The detector operates at the Large Hadron Collider (LHC) at CERN. It was conceived to study proton-proton (and lead-lead) collisions at a centre-of-mass energy of 14 TeV (5.5 TeV nucleon-nucleon) and at luminosities up to 1034 cm-2 s-1 (1027 cm-2 s-1). At the core of the CMS detector sits a high-magnetic-field and large-bore superconducting solenoid surrounding an all-silicon pixel and strip tracker, a lead-tungstate scintillating-crystals electromagnetic calorimeter, and a brass-scintillator sampling hadron calorimeter. The iron yoke of the flux-return is instrumented with four stations of muon detectors covering most of the 4π solid angle. Forward sampling calorimeters extend the pseudorapidity coverage to high values (|η| <= 5) assuring very good hermeticity. The overall dimensions of the CMS detector are a length of 21.6 m, a diameter of 14.6 m and a total weight of 12500 t.

Scale out databases for CERN use cases

NASA Astrophysics Data System (ADS)

Baranowski, Zbigniew; Grzybek, Maciej; Canali, Luca; Lanza Garcia, Daniel; Surdy, Kacper

2015-12-01

Data generation rates are expected to grow very fast for some database workloads going into LHC run 2 and beyond. In particular this is expected for data coming from controls, logging and monitoring systems. Storing, administering and accessing big data sets in a relational database system can quickly become a very hard technical challenge, as the size of the active data set and the number of concurrent users increase. Scale-out database technologies are a rapidly developing set of solutions for deploying and managing very large data warehouses on commodity hardware and with open source software. In this paper we will describe the architecture and tests on database systems based on Hadoop and the Cloudera Impala engine. We will discuss the results of our tests, including tests of data loading and integration with existing data sources and in particular with relational databases. We will report on query performance tests done with various data sets of interest at CERN, notably data from the accelerator log database.

SHiP: a new facility to search for heavy neutrinos and study ντ properties

NASA Astrophysics Data System (ADS)

De Serio, M.; SHiP Collaboration

2016-05-01

SHiP (Search for Hidden Particles) is a newly designed fixed target facility, proposed at the CERN SPS accelerator, with the aim of complementing searches for New Physics at LHC by searching for light long-lived exotic particles with masses below a few GeV/c2. The sensitivity to Heavy Neutrinos will allow for the first time probing a region of the parameter space where Baryogenesis and active neutrino masses and oscillation could also be explained. A dedicated detector, based on OPERA-like bricks, will provide the first observation of the tau anti-neutrino. Moreover, ντ and ν¯τ cross-sections will be measured with a statistics 1000 times larger than currently available data and will allow extracting the F4 and F5 structure functions, never measured so far. Charm physics studies will be performed with significantly improved accuracy with respect to past experiments.

The beam test of muon detector parameters for the SHiP experiment at CERN

NASA Astrophysics Data System (ADS)

Likhacheva, V. L.; Kudenko, Yu. G.; Mefodiev, A. V.; Mineev, O. V.; Khotyantsev, A. N.

2018-01-01

Scintillation detectors based on extruded plastics have been tested in a 10 GeV/c beam at CERN. The scintillation signal readout was provided using optical wavelength shifting fibers Y11 Kuraray and Hamamatsu MPPC micropixel avalanche photodiodes. The light yield was scanned along and across the detectors. Time resolution was found by fitting the MPPC digitized pulse rise and other methods.

First results from the CERN axion solar telescope.

PubMed

Zioutas, K; Andriamonje, S; Arsov, V; Aune, S; Autiero, D; Avignone, F T; Barth, K; Belov, A; Beltrán, B; Bräuninger, H; Carmona, J M; Cebrián, S; Chesi, E; Collar, J I; Creswick, R; Dafni, T; Davenport, M; Di Lella, L; Eleftheriadis, C; Englhauser, J; Fanourakis, G; Farach, H; Ferrer, E; Fischer, H; Franz, J; Friedrich, P; Geralis, T; Giomataris, I; Gninenko, S; Goloubev, N; Hasinoff, M D; Heinsius, F H; Hoffmann, D H H; Irastorza, I G; Jacoby, J; Kang, D; Königsmann, K; Kotthaus, R; Krcmar, M; Kousouris, K; Kuster, M; Lakić, B; Lasseur, C; Liolios, A; Ljubicić, A; Lutz, G; Luzón, G; Miller, D W; Morales, A; Morales, J; Mutterer, M; Nikolaidis, A; Ortiz, A; Papaevangelou, T; Placci, A; Raffelt, G; Ruz, J; Riege, H; Sarsa, M L; Savvidis, I; Serber, W; Serpico, P; Semertzidis, Y; Stewart, L; Vieira, J D; Villar, J; Walckiers, L; Zachariadou, K

2005-04-01

Hypothetical axionlike particles with a two-photon interaction would be produced in the sun by the Primakoff process. In a laboratory magnetic field ("axion helioscope"), they would be transformed into x-rays with energies of a few keV. Using a decommissioned Large Hadron Collider test magnet, the CERN Axion Solar Telescope ran for about 6 months during 2003. The first results from the analysis of these data are presented here. No signal above background was observed, implying an upper limit to the axion-photon coupling g(agamma)<1.16x10(-10) GeV-1 at 95% C.L. for m(a) less, similar 0.02 eV. This limit, assumption-free, is comparable to the limit from stellar energy-loss arguments and considerably more restrictive than any previous experiment over a broad range of axion masses.

Radiation protection challenges in the management of radioactive waste from high-energy accelerators.

PubMed

Ulrici, Luisa; Algoet, Yvon; Bruno, Luca; Magistris, Matteo

2015-04-01

The European Laboratory for Particle Physics (CERN) has operated high-energy accelerators for fundamental physics research for nearly 60 y. The side-product of this activity is the radioactive waste, which is mainly generated as a result of preventive and corrective maintenance, upgrading activities and the dismantling of experiments or accelerator facilities. Prior to treatment and disposal, it is common practice to temporarily store radioactive waste on CERN's premises and it is a legal requirement that these storage facilities are safe and secure. Waste treatment typically includes sorting, segregation, volume and size reduction and packaging, which will depend on the type of component, its chemical composition, residual activity and possible surface contamination. At CERN, these activities are performed in a dedicated waste treatment centre under the supervision of the Radiation Protection Group. This paper gives an overview of the radiation protection challenges in the conception of a temporary storage and treatment centre for radioactive waste in an accelerator facility, based on the experience gained at CERN. The CERN approach consists of the classification of waste items into 'families' with similar radiological and physical-chemical properties. This classification allows the use of specific, family-dependent techniques for radiological characterisation and treatment, which are simultaneously efficient and compliant with best practices in radiation protection. The storage was planned on the basis of radiological and other possible hazards such as toxicity, pollution and fire load. Examples are given of technical choices for the treatment and radiological characterisation of selected waste families, which could be of interest to other accelerator facilities. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Controlled longitudinal emittance blow-up using band-limited phase noise in CERN PSB

NASA Astrophysics Data System (ADS)

Quartullo, D.; Shaposhnikova, E.; Timko, H.

2017-07-01

Controlled longitudinal emittance blow-up (from 1 eVs to 1.4 eVs) for LHC beams in the CERN PS Booster is currently achievied using sinusoidal phase modulation of a dedicated high-harmonic RF system. In 2021, after the LHC injectors upgrade, 3 eVs should be extracted to the PS. Even if the current method may satisfy the new requirements, it relies on low-power level RF improvements. In this paper another method of blow-up was considered, that is the injection of band-limited phase noise in the main RF system (h=1), never tried in PSB but already used in CERN SPS and LHC, under different conditions (longer cycles). This technique, which lowers the peak line density and therefore the impact of intensity effects in the PSB and the PS, can also be complementary to the present method. The longitudinal space charge, dominant in the PSB, causes significant synchrotron frequency shifts with intensity, and its effect should be taken into account. Another complication arises from the interaction of the phase loop with the injected noise, since both act on the RF phase. All these elements were studied in simulations of the PSB cycle with the BLonD code, and the required blow-up was achieved.

Reliable Facility Location Problem with Facility Protection

PubMed Central

Tang, Luohao; Zhu, Cheng; Lin, Zaili; Shi, Jianmai; Zhang, Weiming

2016-01-01

This paper studies a reliable facility location problem with facility protection that aims to hedge against random facility disruptions by both strategically protecting some facilities and using backup facilities for the demands. An Integer Programming model is proposed for this problem, in which the failure probabilities of facilities are site-specific. A solution approach combining Lagrangian Relaxation and local search is proposed and is demonstrated to be both effective and efficient based on computational experiments on random numerical examples with 49, 88, 150 and 263 nodes in the network. A real case study for a 100-city network in Hunan province, China, is presented, based on which the properties of the model are discussed and some managerial insights are analyzed. PMID:27583542

Global atmospheric particle formation from CERN CLOUD measurements.

PubMed

Dunne, Eimear M; Gordon, Hamish; Kürten, Andreas; Almeida, João; Duplissy, Jonathan; Williamson, Christina; Ortega, Ismael K; Pringle, Kirsty J; Adamov, Alexey; Baltensperger, Urs; Barmet, Peter; Benduhn, Francois; Bianchi, Federico; Breitenlechner, Martin; Clarke, Antony; Curtius, Joachim; Dommen, Josef; Donahue, Neil M; Ehrhart, Sebastian; Flagan, Richard C; Franchin, Alessandro; Guida, Roberto; Hakala, Jani; Hansel, Armin; Heinritzi, Martin; Jokinen, Tuija; Kangasluoma, Juha; Kirkby, Jasper; Kulmala, Markku; Kupc, Agnieszka; Lawler, Michael J; Lehtipalo, Katrianne; Makhmutov, Vladimir; Mann, Graham; Mathot, Serge; Merikanto, Joonas; Miettinen, Pasi; Nenes, Athanasios; Onnela, Antti; Rap, Alexandru; Reddington, Carly L S; Riccobono, Francesco; Richards, Nigel A D; Rissanen, Matti P; Rondo, Linda; Sarnela, Nina; Schobesberger, Siegfried; Sengupta, Kamalika; Simon, Mario; Sipilä, Mikko; Smith, James N; Stozkhov, Yuri; Tomé, Antonio; Tröstl, Jasmin; Wagner, Paul E; Wimmer, Daniela; Winkler, Paul M; Worsnop, Douglas R; Carslaw, Kenneth S

2016-12-02

Fundamental questions remain about the origin of newly formed atmospheric aerosol particles because data from laboratory measurements have been insufficient to build global models. In contrast, gas-phase chemistry models have been based on laboratory kinetics measurements for decades. We built a global model of aerosol formation by using extensive laboratory measurements of rates of nucleation involving sulfuric acid, ammonia, ions, and organic compounds conducted in the CERN CLOUD (Cosmics Leaving Outdoor Droplets) chamber. The simulations and a comparison with atmospheric observations show that nearly all nucleation throughout the present-day atmosphere involves ammonia or biogenic organic compounds, in addition to sulfuric acid. A considerable fraction of nucleation involves ions, but the relatively weak dependence on ion concentrations indicates that for the processes studied, variations in cosmic ray intensity do not appreciably affect climate through nucleation in the present-day atmosphere. Copyright © 2016, American Association for the Advancement of Science.

Lectures from the European RTN Winter School on Strings, Supergravity and Gauge Fields, CERN, 15 19 January 2007

NASA Astrophysics Data System (ADS)

Derendinger, J.-P.; Scrucca, C. A.; Uranga, A.

2007-11-01

This special issue is devoted to the proceedings of the conference 'Winter School on Strings, Supergravity and Gauge Theories', which took place at CERN, the European Centre for Nuclear Research, in Geneva, Switzerland, from the 15 to the 19 of January 2007. This event was organized in the framework of the European Mobility Research and Training Network entitled 'Constituents, Fundamental Forces and Symmetries of the Universe'. It is part of a yearly series of scientific schools, which represents what is by now a well established tradition. The previous conferences have been held at SISSA, in Trieste, Italy, in February 2005 and at CERN in January 2006. The next will again take place at CERN, in January 2008. The school was primarily meant for young doctoral students and postdoctoral researchers working in the area of string theory. It consisted of several general lectures of four hours each, the notes of which are published in the present proceedings, and seven working group discussion sessions, focused on specific topics of the network research program. It was attended by approximatively 250 participants. The topics of the lectures were chosen to provide an introduction to some of the areas of recent progress, and to the open problems, in string theory. String theory is a compelling candidate for a theory of all interactions. A basic challenge in this field is therefore to explore the connection of string theory models and the laws of physics in different realms, like high-energy particle physics, early cosmology, or physics of strongly coupled gauge theories. Concerning the exploration of string theory compactifications leading to realistic models of particle physics, one of the main obstacles in this direction is the proper understanding of supersymmetry breaking. The lecture notes by Nathan Seiberg review the realization of spontaneous breaking of supersymmetry in field theory, including recent developments via the use of meta-stable long-lived vacua. It is

Accelerator controls at CERN: Some converging trends

NASA Astrophysics Data System (ADS)

Kuiper, B.

1990-08-01

CERN's growing services to the high-energy physics community using frozen resources has led to the implementation of "Technical Boards", mandated to assist the management by making recommendations for rationalizations in various technological domains. The Board on Process Control and Electronics for Accelerators, TEBOCO, has emphasized four main lines which might yield economy in resources. First, a common architecture for accelerator controls has been agreed between the three accelerator divisions. Second, a common hardware/software kit has been defined, from which the large majority of future process interfacing may be composed. A support service for this kit is an essential part of the plan. Third, high-level protocols have been developed for standardizing access to process devices. They derive from agreed standard models of the devices and involve a standard control message. This should ease application development and mobility of equipment. Fourth, a common software engineering methodology and a commercial package of application development tools have been adopted. Some rationalization in the field of the man-machine interface and in matters of synchronization is also under way.

Diffractive Higgs boson production at the Fermilab Tevatron and the CERN Large Hadron Collider.

PubMed

Enberg, R; Ingelman, G; Kissavos, A; Tîmneanu, N

2002-08-19

Improved possibilities to find the Higgs boson in diffractive events, having less hadronic activity, depend on whether the cross section is large enough. Based on the soft color interaction models that successfully describe diffractive hard scattering at DESY HERA and the Fermilab Tevatron, we find that only a few diffractive Higgs events may be produced at the Tevatron, but we predict a substantial rate at the CERN Large Hadron Collider.

Strategies for halting the rise of multidrug resistant TB epidemics: assessing the effect of early case detection and isolation.

PubMed

Espindola, Aquino L; Varughese, Marie; Laskowski, Marek; Shoukat, Affan; Heffernan, Jane M; Moghadas, Seyed M

2017-03-01

The increasing rates of multidrug resistant TB (MDR-TB) have posed the question of whether control programs under enhanced directly observed treatment, short-course (DOTS-Plus) are sufficient or implemented optimally. Despite enhanced efforts on early case detection and improved treatment regimens, direct transmission of MDR-TB remains a major hurdle for global TB control. We developed an agent-based simulation model of TB dynamics to evaluate the effect of transmission reduction measures on the incidence of MDR-TB. We implemented a 15-day isolation period following the start of treatment in active TB cases. The model was parameterized with the latest estimates derived from the published literature. We found that if high rates (over 90%) of TB case identification are achieved within 4 weeks of developing active TB, then a 15-day patient isolation strategy with 50% effectiveness in interrupting disease transmission leads to 10% reduction in the incidence of MDR-TB over 10 years. If transmission is fully prevented, the rise of MDR-TB can be halted within 10 years, but the temporal reduction of MDR-TB incidence remains below 20% in this period. The impact of transmission reduction measures on the TB incidence depends critically on the rates and timelines of case identification. The high costs and adverse effects associated with MDR-TB treatment warrant increased efforts and investments on measures that can interrupt direct transmission through early case detection. © The Author 2017. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Anomalous single production of the fourth generation quarks at the CERN LHC

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ciftci, R.

Possible anomalous single productions of the fourth standard model generation up and down type quarks at CERN Large Hadron Collider are studied. Namely, pp{yields}u{sub 4}(d{sub 4})X with subsequent u{sub 4}{yields}bW{sup +} process followed by the leptonic decay of the W boson and d{sub 4}{yields}b{gamma} (and its H.c.) decay channel are considered. Signatures of these processes and corresponding standard model backgrounds are discussed in detail. Discovery limits for the quark mass and achievable values of the anomalous coupling strength are determined.

W production at large transverse momentum at the CERN Large Hadron Collider.

PubMed

Gonsalves, Richard J; Kidonakis, Nikolaos; Sabio Vera, Agustín

2005-11-25

We study the production of W bosons at large transverse momentum in pp collisions at the CERN Large Hadron Collider. We calculate the complete next-to-leading order (NLO) corrections to the differential cross section. We find that the NLO corrections provide a large increase to the cross section but, surprisingly, do not reduce the scale dependence relative to leading order (LO). We also calculate next-to-next-to-leading-order (NNLO) soft-gluon corrections and find that, although they are small, they significantly reduce the scale dependence thus providing a more stable result.

Lower limit on dark matter production at the CERN Large Hadron Collider.

PubMed

Feng, Jonathan L; Su, Shufang; Takayama, Fumihiro

2006-04-21

We evaluate the prospects for finding evidence of dark matter production at the CERN Large Hadron Collider. We consider weakly interacting massive particles (WIMPs) and superWIMPs and characterize their properties through model-independent parametrizations. The observed relic density then implies lower bounds on dark matter production rates as functions of a few parameters. For WIMPs, the resulting signal is indistinguishable from background. For superWIMPs, however, this analysis implies significant production of metastable charged particles. For natural parameters, these rates may far exceed Drell-Yan cross sections and yield spectacular signals.

First experience with carbon stripping foils for the 160 MeV H- injection into the CERN PSB

NASA Astrophysics Data System (ADS)

Weterings, Wim; Bracco, Chiara; Jorat, Louise; Noulibos, Remy; van Trappen, Pieter

2018-05-01

160 MeV H- beam will be delivered from the new CERN linear accelerator (Linac4) to the Proton Synchrotron Booster (PSB), using a H- charge-exchange injection system. A 200 µg/cm2 carbon stripping foil will convert H- into protons by stripping off the electrons. The H- charge-exchange injection principle will be used for the first time in the CERN accelerator complex and involves many challenges. In order to gain experience with the foil changing mechanism and the very fragile foils, in 2016, prior to the installation in the PSB, a stripping foil test stand has been installed in the Linac4 transfer line. In addition, parts of the future PSB injection equipment are also temporarily installed in the Linac4 transfer line for tests with a 160 MeV H- commissioning proton beam. This paper describes the foil changing mechanism and control system, summarizes the practical experience of gluing and handling these foils and reports on the first results with beam.

Temperature characterisation of the CLOUD chamber at CERN

NASA Astrophysics Data System (ADS)

Dias, A. M.; Almeida, J.; Kirkby, J.; Mathot, S.; Onnela, A.; Vogel, A.; Ehrhart, S.

2014-12-01

Temperature stability, uniformity and absolute scale inside the CLOUD (Cosmics Leaving OUtdoor Droplets) chamber at CERN are important for experiments on aerosol particle nucleation and ice/liquid cloud formation. In order to measure the air temperature, a comprehensive set of arrays ("strings") of platinum resistance thermometers, thermocouples and optical sensors have been installed inside the 26 m3 chamber. The thermal sensors must meet several challenging design requirements: ultra-clean materials, 0.01 K measurement sensitivity, high absolute precision (<0.1 K), 200 K - 373 K range, ability to operate in high electric fields (20 kV/m), and fast response in air (~1 s) in order to measure rapid changes of temperature during ice/liquid cloud formation in the chamber by adiabatic pressure reductions. This presentation will focus on the design of the thermometer strings and the thermal performance of the chamber during the CLOUD8 and CLOUD9 campaigns, 2013-2014, together with the planned upgrades of the CLOUD thermal system.

Live Webcasts from CERN and ESO for European Science and Technology Week

NASA Astrophysics Data System (ADS)

2002-10-01

Visit http://www.cern.ch/sci-tech on 7 - 8 November to find out what modern Europeans can't live without. Seven of Europe's leading Research Organizations [1] are presenting three live Webcasts from CERN in a joint outreach programme for the European Science and Technology Week . The aim of Sci-Tech... couldn't be without it! is to show how today's society couldn't be without cutting-edge scientific research. See also ESO Press Release 05/02. Northern Europeans can't imagine their households without ovens, whereas Southern Europeans identify the refrigerator as the most essential household appliance. In the area of communications, cars and motorbikes are clearly the technologies of choice in Italy, but are regarded as less important in countries like Norway and Germany. For entertainment, the personal computer is a clear winner as the device is considered most essential by all Europeans, followed by the TV and the Internet. This hit parade of technological marvels is the result of a phone and online survey conducted by the Sci-Tech... couldn't be without it! team for this year's European Science and Technology Week on 4-10 November. The technologies Europeans could not be without, form the starting point of three entertaining and informative Webcast shows in Italian (Thursday 7 November at 10:00 CET), French (Thursday 7 November at 15:00 CET) and English (Friday 8 November at 15:00 CET), broadcast live on the Internet from a studio at CERN. During these Webcasts scientists from the seven research Organizations and their industrial partners Sun Microsystems, Siemens, L'Oreal and Luminex will engage - from the CERN studio or from remote locations through teleconference links - an audience of Internauts all over the world. The public will be taken inside their most popular gadgets to discover the science that made them possible and how vital fundamental research has been in the creation of modern technology. Fundamental science will be brought as close as possible to

Analysis of SEL on Commercial SRAM Memories and Mixed-Field Characterization of a Latchup Detection Circuit for LEO Space Applications

NASA Astrophysics Data System (ADS)

Secondo, R.; Alía, R. Garcia; Peronnard, P.; Brugger, M.; Masi, A.; Danzeca, S.; Merlenghi, A.; Vaillé, J.-R.; Dusseau, L.

2017-08-01

A single event latchup (SEL) experiment based on commercial static random access memory (SRAM) memories has recently been proposed in the framework of the European Organization for Nuclear Research (CERN) Latchup Experiment and Student Satellite nanosatellite low Earth orbit (LEO) space mission. SEL characterization of three commercial SRAM memories has been carried out at the Paul Scherrer Institut (PSI) facility, using monoenergetic focused proton beams and different acquisition setups. The best target candidate was selected and a circuit for SEL detection has been proposed and tested at CERN, in the CERN High Energy AcceleRator Mixed-field facility (CHARM). Experimental results were carried out at test locations representative of the LEO environment, thus providing a full characterization of the SRAM cross sections, together with the analysis of the single-event effect and total ionizing dose of the latchup detection circuit in relation to the particle spectra expected during mission. The setups used for SEL monitoring are described, and details of the proposed circuit components and topology are presented. Experimental results obtained both at PSI and at CHARM facilities are discussed.

National facilities study. Volume 4: Space operations facilities task group

NASA Technical Reports Server (NTRS)

1994-01-01

The principal objectives of the National Facilities Study (NFS) were to: (1) determine where U.S. facilities do not meet national aerospace needs; (2) define new facilities required to make U.S. capabilities 'world class' where such improvements are in the national interest; (3) define where consolidation and phase-out of existing facilities is appropriate; and (4) develop a long-term national plan for world-class facility acquisition and shared usage. The Space Operations Facilities Task Group defined discrete tasks to accomplish the above objectives within the scope of the study. An assessment of national space operations facilities was conducted to determine the nation's capability to meet the requirements of space operations during the next 30 years. The mission model used in the study to define facility requirements is described in Volume 3. Based on this model, the major focus of the Task Group was to identify any substantive overlap or underutilization of space operations facilities and to identify any facility shortfalls that would necessitate facility upgrades or new facilities. The focus of this initial study was directed toward facility recommendations related to consolidations, closures, enhancements, and upgrades considered necessary to efficiently and effectively support the baseline requirements model. Activities related to identifying facility needs or recommendations for enhancing U.S. international competitiveness and achieving world-class capability, where appropriate, were deferred to a subsequent study phase.

Dance Facilities.

ERIC Educational Resources Information Center

Ashton, Dudley, Ed.; Irey, Charlotte, Ed.

This booklet represents an effort to assist teachers and administrators in the professional planning of dance facilities and equipment. Three chapters present the history of dance facilities, provide recommended dance facilities and equipment, and offer some adaptations of dance facilities and equipment, for elementary, secondary and college level…

Identification of diverse defense mechanisms in rainbow trout red blood cells in response to halted replication of VHS virus.

PubMed

Nombela, Ivan; Puente-Marin, Sara; Chico, Veronica; Villena, Alberto J; Carracedo, Begoña; Ciordia, Sergio; Mena, Maria Carmen; Mercado, Luis; Perez, Luis; Coll, Julio; Estepa, Amparo; Ortega-Villaizan, Maria Del Mar

2017-01-01

Background: It has been described that fish nucleated red blood cells (RBCs) generate a wide variety of immune-related gene transcripts when viruses highly replicate inside them and are their main target cell. The immune response and mechanisms of fish RBCs against viruses targeting other cells or tissues has not yet been explored and is the objective of our study. Methods: Rainbow trout RBCs were obtained from peripheral blood, ficoll purified and exposed to Viral Haemorrhagic Septicaemia virus (VHSV). Immune response was evaluated by means of RT-qPCR, flow cytometry, immunofluorescence and isobaric tag for relative and absolute quantification (iTRAQ) protein profiling. Results: VHSV N gene transcripts incremented early postexposure and were drastically decreased after 6 hours postexposure (hpe). The expression of type I interferon ( ifn1 ) gene was significantly downregulated at early postexposure (3 hpe), together with a gradual downregulation of interferon-inducible mx and pkr genes until 72 hpe. Type I IFN protein was downregulated and interferon-inducible Mx protein was maintained at basal levels. Co-culture assays of RBCs, previously exposed to UV-inactivated VHSV, and TSS (stromal cell line from spleen) revealed IFN crosstalk between both cell types. On the other hand, anti-microbial peptide β-defensin 1 and neutrophil chemotactic factor interleukin 8 were slightly upregulated in VHSV-exposed RBCs. iTRAQ profiling revealed that VHSV exposure can induce a global protein downregulation in rainbow trout RBCs, mainly related to RNA stability and proteasome pathways. Antioxidant/antiviral response is also suggested to be involved in the response of rainbow trout RBCs to VHSV. Conclusions: A variety of mechanisms are proposed to be implicated in the antiviral response of rainbow trout RBCs against VHSV halted infection. Ongoing research is focused on understanding the mechanisms in detail.

Identification of diverse defense mechanisms in rainbow trout red blood cells in response to halted replication of VHS virus

PubMed Central

Nombela, Ivan; Puente-Marin, Sara; Chico, Veronica; Villena, Alberto J.; Carracedo, Begoña; Ciordia, Sergio; Mena, Maria Carmen; Mercado, Luis; Perez, Luis; Coll, Julio; Ortega-Villaizan, Maria del Mar

2018-01-01

Background: It has been described that fish nucleated red blood cells (RBCs) generate a wide variety of immune-related gene transcripts when viruses highly replicate inside them and are their main target cell. The immune response and mechanisms of fish RBCs against viruses targeting other cells or tissues has not yet been explored and is the objective of our study. Methods: Rainbow trout RBCs were obtained from peripheral blood, ficoll purified and exposed to Viral Haemorrhagic Septicaemia virus (VHSV). Immune response was evaluated by means of RT-qPCR, flow cytometry, immunofluorescence and isobaric tag for relative and absolute quantification (iTRAQ) protein profiling. Results: VHSV N gene transcripts incremented early postexposure and were drastically decreased after 6 hours postexposure (hpe). The expression of type I interferon ( ifn1) gene was significantly downregulated at early postexposure (3 hpe), together with a gradual downregulation of interferon-inducible mx and pkr genes until 72 hpe. Type I IFN protein was downregulated and interferon-inducible Mx protein was maintained at basal levels. Co-culture assays of RBCs, previously exposed to UV-inactivated VHSV, and TSS (stromal cell line from spleen) revealed IFN crosstalk between both cell types. On the other hand, anti-microbial peptide β-defensin 1 and neutrophil chemotactic factor interleukin 8 were slightly upregulated in VHSV-exposed RBCs. iTRAQ profiling revealed that VHSV exposure can induce a global protein downregulation in rainbow trout RBCs, mainly related to RNA stability and proteasome pathways. Antioxidant/antiviral response is also suggested to be involved in the response of rainbow trout RBCs to VHSV. Conclusions: A variety of mechanisms are proposed to be implicated in the antiviral response of rainbow trout RBCs against VHSV halted infection. Ongoing research is focused on understanding the mechanisms in detail. PMID:29527292

Hangout with CERN: Reaching the Public with the Collaborative Tools of Social Media

NASA Astrophysics Data System (ADS)

Goldfarb, S.; Kahle, K. L. M.; Rao, A.

2014-06-01

On 4 July 2012, particle physics became a celebrity. Around 1,000,000,000 people (yes, 1 billion) [1] saw rebroadcasts of two technical presentations announcing the discovery of a new boson. The occasion was a joint seminar of the CMS [2] and ATLAS [3] collaborations, and the target audience were particle physicists. Yet the world ate it up like a sporting event. Roughly two days later, in a parallel session of ICHEP in Melbourne, Australia [4], a group of physicists decided to explain the significance of this discovery to the public. They used a tool called "Hangout", part of the relatively new Google+ social media platform [5], to converse directly with the public via a webcast videoconference. The demand to join this Hangout [6] overloaded the server several times. In the end, a compromise involving Q&A via comments was set up, and the conversation was underway. We present a new project born shortly after this experience called Hangout with CERN [7], and discuss its success in creating an effective conversational channel between the public and particle physicists. We review earlier efforts by both CMS and ATLAS contributing to this development, and then describe the current programme, involving nearly all aspects of CERN, and some topics that go well beyond that. We conclude by discussing the potential of the programme both to improve our accountability to the public and to train our community for public communication.

Future carbon beams at SPIRAL1 facility: Which method is the most efficient?

NASA Astrophysics Data System (ADS)

Maunoury, L.; Delahaye, P.; Angot, J.; Dubois, M.; Dupuis, M.; Frigot, R.; Grinyer, J.; Jardin, P.; Leboucher, C.; Lamy, T.

2014-02-01

Compared to in-flight facilities, Isotope Separator On-Line ones can in principle produce significantly higher radioactive ion beam intensities. On the other hand, they have to cope with delays for the release and ionization which make the production of short-lived isotopes ion beams of reactive and refractory elements particularly difficult. Many efforts are focused on extending the capabilities of ISOL facilities to those challenging beams. In this context, the development of carbon beams is triggering interest [H. Frånberg, M. Ammann, H. W. Gäggeler, and U. Köster, Rev. Sci. Instrum. 77, 03A708 (2006); M. Kronberger, A. Gottberg, T. M. Mendonca, J. P. Ramos, C. Seiffert, P. Suominen, and T. Stora, in Proceedings of the EMIS 2012 [Nucl. Instrum. Methods Phys. Res. B Production of molecular sideband radioisotope beams at CERN-ISOLDE using a Helicon-type plasma ion source (to be published)]: despite its refractory nature, radioactive carbon beams can be produced from molecules (CO or CO2), which can subsequently be broken up and multi-ionized to the required charge state in charge breeders or ECR sources. This contribution will present results of experiments conducted at LPSC with the Phoenix charge breeder and at GANIL with the Nanogan ECR ion source for the ionization of carbon beams in the frame of the ENSAR and EMILIE projects. Carbon is to date the lightest condensable element charge bred with an ECR ion source. Charge breeding efficiencies will be compared with those obtained using Nanogan ECRIS and charge breeding times will be presented as well.

Future carbon beams at SPIRAL1 facility: which method is the most efficient?

PubMed

Maunoury, L; Delahaye, P; Angot, J; Dubois, M; Dupuis, M; Frigot, R; Grinyer, J; Jardin, P; Leboucher, C; Lamy, T

2014-02-01

Compared to in-flight facilities, Isotope Separator On-Line ones can in principle produce significantly higher radioactive ion beam intensities. On the other hand, they have to cope with delays for the release and ionization which make the production of short-lived isotopes ion beams of reactive and refractory elements particularly difficult. Many efforts are focused on extending the capabilities of ISOL facilities to those challenging beams. In this context, the development of carbon beams is triggering interest [H. Frånberg, M. Ammann, H. W. Gäggeler, and U. Köster, Rev. Sci. Instrum. 77, 03A708 (2006); M. Kronberger, A. Gottberg, T. M. Mendonca, J. P. Ramos, C. Seiffert, P. Suominen, and T. Stora, in Proceedings of the EMIS 2012 [Nucl. Instrum. Methods Phys. Res. B Production of molecular sideband radioisotope beams at CERN-ISOLDE using a Helicon-type plasma ion source (to be published)]: despite its refractory nature, radioactive carbon beams can be produced from molecules (CO or CO2), which can subsequently be broken up and multi-ionized to the required charge state in charge breeders or ECR sources. This contribution will present results of experiments conducted at LPSC with the Phoenix charge breeder and at GANIL with the Nanogan ECR ion source for the ionization of carbon beams in the frame of the ENSAR and EMILIE projects. Carbon is to date the lightest condensable element charge bred with an ECR ion source. Charge breeding efficiencies will be compared with those obtained using Nanogan ECRIS and charge breeding times will be presented as well.

The beam and detector of the NA62 experiment at CERN

NASA Astrophysics Data System (ADS)

Cortina Gil, E.; Martín Albarrán, E.; Minucci, E.; Nüssle, G.; Padolski, S.; Petrov, P.; Szilasi, N.; Velghe, B.; Georgiev, G.; Kozhuharov, V.; Litov, L.; Husek, T.; Kampf, K.; Zamkovsky, M.; Aliberti, R.; Geib, K. H.; Khoriauli, G.; Kleinknecht, K.; Kunze, J.; Lomidze, D.; Marchevski, R.; Peruzzo, L.; Vormstein, M.; Wanke, R.; Winhart, A.; Bolognesi, M.; Carassiti, V.; Chiozzi, S.; Cotta Ramusino, A.; Gianoli, A.; Malaguti, R.; Dalpiaz, P.; Fiorini, M.; Gamberini, E.; Neri, I.; Norton, A.; Petrucci, F.; Statera, M.; Wahl, H.; Bucci, F.; Ciaranfi, R.; Lenti, M.; Maletta, F.; Volpe, R.; Bizzeti, A.; Cassese, A.; Iacopini, E.; Antonelli, A.; Capitolo, E.; Capoccia, C.; Cecchetti, A.; Corradi, G.; Fascianelli, V.; Gonnella, F.; Lamanna, G.; Lenci, R.; Mannocchi, G.; Martellotti, S.; Moulson, M.; Paglia, C.; Raggi, M.; Russo, V.; Santoni, M.; Spadaro, T.; Tagnani, D.; Valeri, S.; Vassilieva, T.; Cassese, F.; Roscilli, L.; Ambrosino, F.; Capussela, T.; Di Filippo, D.; Massarotti, P.; Mirra, M.; Napolitano, M.; Saracino, G.; Barbanera, M.; Cenci, P.; Checcucci, B.; Duk, V.; Farnesini, L.; Gersabeck, E.; Lupi, M.; Papi, A.; Pepe, M.; Piccini, M.; Scolieri, G.; Aisa, D.; Anzivino, G.; Bizzarri, M.; Campeggi, C.; Imbergamo, E.; Piluso, A.; Santoni, C.; Berretta, L.; Bianucci, S.; Burato, A.; Cerri, C.; Fantechi, R.; Galeotti, S.; Magazzu', G.; Minuti, M.; Orsini, A.; Petragnani, G.; Pontisso, L.; Raffaelli, F.; Spinella, F.; Collazuol, G.; Mannelli, I.; Avanzini, C.; Costantini, F.; Di Lella, L.; Doble, N.; Giorgi, M.; Giudici, S.; Pedreschi, E.; Piandani, R.; Pierazzini, G.; Pinzino, J.; Sozzi, M.; Zaccarelli, L.; Biagioni, A.; Leonardi, E.; Lonardo, A.; Valente, P.; Vicini, P.; D'Agostini, G.; Ammendola, R.; Bonaiuto, V.; De Simone, N.; Federici, L.; Fucci, A.; Paoluzzi, G.; Salamon, A.; Salina, G.; Sargeni, F.; Biino, C.; Dellacasa, G.; Garbolino, S.; Marchetto, F.; Martoiu, S.; Mazza, G.; Rivetti, A.; Arcidiacono, R.; Bloch-Devaux, B.; Boretto, M.; Iacobuzio, L.; Menichetti, E.; Soldi, D.; Engelfried, J.; Estrada-Tristan, N.; Bragadireanu, A. M.; Hutanu, O. E.; Azorskiy, N.; Elsha, V.; Enik, T.; Falaleev, V.; Glonti, L.; Gusakov, Y.; Kakurin, S.; Kekelidze, V.; Kilchakovskaya, S.; Kislov, E.; Kolesnikov, A.; Madigozhin, D.; Misheva, M.; Movchan, S.; Polenkevich, I.; Potrebenikov, Y.; Samsonov, V.; Shkarovskiy, S.; Sotnikov, S.; Tarasova, L.; Zaytseva, M.; Zinchenko, A.; Bolotov, V.; Fedotov, S.; Gushin, E.; Khotjantsev, A.; Khudyakov, A.; Kleimenova, A.; Kudenko, Yu.; Shaikhiev, A.; Gorin, A.; Kholodenko, S.; Kurshetsov, V.; Obraztsov, V.; Ostankov, A.; Rykalin, V.; Semenov, V.; Sugonyaev, V.; Yushchenko, O.; Bician, L.; Blazek, T.; Cerny, V.; Koval, M.; Lietava, R.; Aglieri Rinella, G.; Arroyo Garcia, J.; Balev, S.; Battistin, M.; Bendotti, J.; Bergsma, F.; Bonacini, S.; Butin, F.; Ceccucci, A.; Chiggiato, P.; Danielsson, H.; Degrange, J.; Dixon, N.; Döbrich, B.; Farthouat, P.; Gatignon, L.; Golonka, P.; Girod, S.; Goncalves Martins De Oliveira, A.; Guida, R.; Hahn, F.; Harrouch, E.; Hatch, M.; Jarron, P.; Jamet, O.; Jenninger, B.; Kaplon, J.; Kluge, A.; Lehmann-Miotto, G.; Lichard, P.; Maire, G.; Mapelli, A.; Morant, J.; Morel, M.; Noël, J.; Noy, M.; Palladino, V.; Pardons, A.; Perez-Gomez, F.; Perktold, L.; Perrin-Terrin, M.; Petagna, P.; Poltorak, K.; Riedler, P.; Romagnoli, G.; Ruggiero, G.; Rutter, T.; Rouet, J.; Ryjov, V.; Saputi, A.; Schneider, T.; Stefanini, G.; Theis, C.; Tiuraniemi, S.; Vareia Rodriguez, F.; Venditti, S.; Vergain, M.; Vincke, H.; Wertelaers, P.; Brunetti, M. B.; Edwards, S.; Goudzovski, E.; Hallgren, B.; Krivda, M.; Lazzeroni, C.; Lurkin, N.; Munday, D.; Newson, F.; Parkinson, C.; Pyatt, S.; Romano, A.; Serghi, X.; Sergi, A.; Staley, R.; Sturgess, A.; Heath, H.; Page, R.; Angelucci, B.; Britton, D.; Protopopescu, D.; Skillicorn, I.; Cooke, P.; Dainton, J. B.; Fry, J. R.; Fulton, L.; Hutchcroft, D.; Jones, E.; Jones, T.; Massri, K.; Maurice, E.; McCormick, K.; Sutcliffe, P.; Wrona, B.; Conovaloff, A.; Cooper, P.; Coward, D.; Rubin, P.; Winston, R.

2017-05-01

NA62 is a fixed-target experiment at the CERN SPS dedicated to measurements of rare kaon decays. Such measurements, like the branching fraction of the K+ → π+ ν bar nu decay, have the potential to bring significant insights into new physics processes when comparison is made with precise theoretical predictions. For this purpose, innovative techniques have been developed, in particular, in the domain of low-mass tracking devices. Detector construction spanned several years from 2009 to 2014. The collaboration started detector commissioning in 2014 and will collect data until the end of 2018. The beam line and detector components are described together with their early performance obtained from 2014 and 2015 data.

Web Based Monitoring in the CMS Experiment at CERN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Badgett, William; Borrello, Laura; Chakaberia, Irakli

2014-09-03

The Compact Muon Solenoid (CMS) is a large and complex general purpose experiment at the CERN Large Hadron Collider (LHC), built and maintained by many collaborators from around the world. Efficient operation of the detector requires widespread and timely access to a broad range of monitoring and status information. To this end the Web Based Monitoring (WBM) system was developed to present data to users located anywhere from many underlying heterogeneous sources, from real time messaging systems to relational databases. This system provides the power to combine and correlate data in both graphical and tabular formats of interest to themore » experimenters, including data such as beam conditions, luminosity, trigger rates, detector conditions, and many others, allowing for flexibility on the user side. This paper describes the WBM system architecture and describes how the system was used during the first major data taking run of the LHC.« less

Lead ions and Coulomb’s Law at the LHC (CERN)

NASA Astrophysics Data System (ADS)

Cid-Vidal, Xabier; Cid, Ramon

2018-03-01

Although for most of the time the Large Hadron Collider (LHC) at CERN collides protons, for around one month every year lead ions are collided, to expand the diversity of the LHC research programme. Furthermore, in an effort not originally foreseen, proton-lead collisions are also taking place, with results of high interest to the physics community. All the large experiments of the LHC have now joined the heavy-ion programme, including the LHCb experiment, which was not at first expected to be part of it. The aim of this article is to introduce a few simple physical calculations relating to some electrical phenomena that occur when lead-ion bunches are running in the LHC, using Coulomb’s Law, to be taken to the secondary school classroom to help students understand some important physical concepts.

Shielding design for the front end of the CERN SPL.

PubMed

Magistris, Matteo; Silari, Marco; Vincke, Helmut

2005-01-01

CERN is designing a 2.2-GeV Superconducting Proton Linac (SPL) with a beam power of 4 MW, to be used for the production of a neutrino superbeam. The SPL front end will initially accelerate 2 x 10(14) negative hydrogen ions per second up to an energy of 120 MeV. The FLUKA Monte Carlo code was employed for shielding design. The proposed shielding is a combined iron-concrete structure, which also takes into consideration the required RF wave-guide ducts and access labyrinths to the machine. Two beam-loss scenarios were investigated: (1) constant beam loss of 1 Wm(-1) over the whole accelerator length and (2) full beam loss occurring at various locations. A comparison with results based on simplified approaches is also presented.

EDITORIAL: Lectures from the European RTN Winter School on Strings, Supergravity and Gauge Theories, CERN, 21 25 January 2008

NASA Astrophysics Data System (ADS)

Derendinger, J.-P.; Orlando, D.; Uranga, A.

2008-11-01

This special issue is devoted to the proceedings of the conference 'RTN Winter School on Strings, Supergravity and Gauge Theories', which took place at CERN, the European Centre for Nuclear Research, in Geneva, Switzerland, on the 21 25 January 2008. This event was organized in the framework of the European Mobility Research and Training Network entitled 'Constituents, Fundamental Forces and Symmetries of the Universe'. It is part of a yearly series of scientific schools, which represents what is by now a well established tradition. The previous ones have been held at SISSA, in Trieste, Italy, in February 2005 and at CERN in January 2006. The next one will again take place at CERN, in February 2009. The school was primarily meant for young doctoral students and postdoctoral researchers working in the area of string theory. It consisted of several general lectures of four hours each, whose notes are published in the present proceedings, and five working group discussion sessions, focused on specific topics of the network research program. It was attended by approximatively 250 participants. The topics of the lectures were chosen to provide an introduction to some of the areas of recent progress, and to the open problems, in string theory. One of the most active areas in string theory in recent years is the AdS/CFT or gauge/gravity correspondence, which proposes the complete equivalence of string theory on (asymptotically) anti-de Sitter spacetimes with gauge theories. The duality relates the weak coupling regime of one system to the strongly coupled regime of the other, and is therefore very non-trivial to test beyond the supersymmetry-protected BPS sector. One of the key ideas to quantitatively match several quantities on both sides is the use of integrability, both in the gauge theory and the string side. The lecture notes by Nick Dorey provide a pedagogical introduction to the fascinating topic of integrability in AdS/CFT. On the string theory side, progress has

An alternative model to distribute VO software to WLCG sites based on CernVM-FS: a prototype at PIC Tier1

NASA Astrophysics Data System (ADS)

Lanciotti, E.; Merino, G.; Bria, A.; Blomer, J.

2011-12-01

In a distributed computing model as WLCG the software of experiment specific application software has to be efficiently distributed to any site of the Grid. Application software is currently installed in a shared area of the site visible for all Worker Nodes (WNs) of the site through some protocol (NFS, AFS or other). The software is installed at the site by jobs which run on a privileged node of the computing farm where the shared area is mounted in write mode. This model presents several drawbacks which cause a non-negligible rate of job failure. An alternative model for software distribution based on the CERN Virtual Machine File System (CernVM-FS) has been tried at PIC, the Spanish Tierl site of WLCG. The test bed used and the results are presented in this paper.

O8.10A MODEL FOR RESEARCH INITIATIVES FOR RARE CANCERS: THE COLLABORATIVE EPENDYMOMA RESEARCH NETWORK (CERN)

PubMed Central

Armstrong, T.S.; Aldape, K.; Gajjar, A.; Haynes, C.; Hirakawa, D.; Gilbertson, R.; Gilbert, M.R.

2014-01-01

Ependymoma represents less than 5% of adult central nervous system (CNS) tumors and a higher percentage of pediatric CNS tumors, but it remains an orphan disease. The majority of the laboratory-based research and clinical trials have been conducted in the pediatric setting, a reflection of the relative incidence and funding opportunities. CERN, created in 2006, was designed to establish a collaborative effort between laboratory and clinical research and pediatric and adult investigators. The organization of CERN is based on integration and collaboration among five projects. Project 1 contains the clinical trials network encompassing both adult and pediatric centers. This group has completed 2 clinical trials with more underway. Project 2 is focused on molecular classification of human ependymoma tumor tissues and also contains the tumor repository which has now collected over 600 fully clinically annotated CNS ependymomas from adults and children. Project 3 is focused on drug discovery utilizing robust laboratory models of ependymoma to perform high throughput screening of drug libraries, then taking promising agents through extensive preclinical testing including monitoring of drug delivery to tumor using state of the art microdialysis. Project 4 contains the basic research efforts evaluating the molecular pathogenesis of ependymoma and has successfully translated these findings by generating the first mouse models of ependymoma that are employed in preclinical drug development in Project 3. Project 5 studies patient outcomes, including the incorporation of these measures in the clinical trials. This project also contains an online Ependymoma Outcomes survey, collecting data on the consequences of the disease and its treatment. These projects have been highly successful and collaborative. For example, the serial measurement of symptom burden (Project 5) has greatly contributed to the evaluation of treatment efficacy of a clinical trial (Project 1) and

Facilities Performance Indicators Report 2013-14: Tracking Your Facilities Vital Signs

ERIC Educational Resources Information Center

APPA: Association of Higher Education Facilities Officers, 2015

2015-01-01

This paper features an expanded Web-based "Facilities Performance Indicators (FPI) Report." The purpose of APPA: Association of Higher Education Facilities Officers (APPA's) Facilities Performance Indicators is to provide a representative set of statistics about facilities in educational institutions. "The Facilities Performance…

Optimising the Active Muon Shield for the SHiP Experiment at CERN

NASA Astrophysics Data System (ADS)

Baranov, A.; Burnaev, E.; Derkach, D.; Filatov, A.; Klyuchnikov, N.; Lantwin, O.; Ratnikov, F.; Ustyuzhanin, A.; Zaitsev, A.

2017-12-01

The SHiP experiment is designed to search for very weakly interacting particles beyond the Standard Model which are produced in a 400 GeV/c proton beam dump at the CERN SPS. The critical challenge for this experiment is to keep the Standard Model background level negligible. In the beam dump, around 1011 muons will be produced per second. The muon rate in the spectrometer has to be reduced by at least four orders of magnitude to avoid muoninduced backgrounds. It is demonstrated that new improved active muon shield may be used to magnetically deflect the muons out of the acceptance of the spectrometer.

Development of radiation tolerant components for the Quench Protection System at CERN

NASA Astrophysics Data System (ADS)

Bitterling, O.; Denz, R.; Steckert, J.; Uznanski, S.

2016-01-01

This paper describes the results of irradiation campaigns with the high resolution Analog to Digital Converter (ADC) ADS1281. This ADC will be used as part of a revised quench detection circuit for the 600 A corrector magnets at the CERN Large Hadron Collider (LHC) . To verify the radiation tolerance of the ADC an irradiation campaign using a proton beam, applying doses up to 3,4 kGy was conducted. The resulting data and an analysis of the found failure modes is discussed in this paper. Several mitigation measures are described that allow to reduce the error rate to levels acceptable for operation as part of the LHC QPS.

Facilities maintenance handbook

NASA Technical Reports Server (NTRS)

1991-01-01

This handbook is a guide for facilities maintenance managers. Its objective is to set minimum facilities maintenance standards. It also provides recommendations on how to meet the standards to ensure that NASA maintains its facilities in a manner that protects and preserves its investment in the facilities in a cost-effective manner while safely and efficiently performing its mission. This handbook implements NMI 8831.1, which states NASA facilities maintenance policy and assigns organizational responsibilities for the management of facilities maintenance activities on all properties under NASA jurisdiction. It is a reference for facilities maintenance managers, not a step-by-step procedural manual. Because of the differences in NASA Field Installation organizations, this handbook does not assume or recommend a typical facilities maintenance organization. Instead, it uses a systems approach to describe the functions that should be included in any facilities maintenance management system, regardless of its organizational structure. For documents referenced in the handbook, the most recent version of the documents is applicable. This handbook is divided into three parts: Part 1 specifies common definitions and facilities maintenance requirements and amplifies the policy requirements contained in NMI 8831. 1; Part 2 provides guidance on how to meet the requirements of Part 1, containing recommendations only; Part 3 contains general facilities maintenance information. One objective of this handbook is to fix commonality of facilities maintenance definitions among the Centers. This will permit the application of uniform measures of facilities conditions, of the relationship between current replacement value and maintenance resources required, and of the backlog of deferred facilities maintenance. The utilization of facilities maintenance system functions will allow the Centers to quantitatively define maintenance objectives in common terms, prepare work plans, and

Recent results from the NA48 experiment at CERN

NASA Astrophysics Data System (ADS)

Shkarovskiy, Sergey; NA48/2 Collaboration

2017-12-01

The NA48/2 experiment presents a final result of the charged kaon semileptonic decays form factors measurement based on 4.28 million Ke3+/- and 2.91 million K{μ3}+/- selected decays collected in 2004. The result is competetive with other measurements in K{μ3}+/- mode and has a smallest uncertainty for Ke3+/- , that leads to the most precise combined Kl3+/- result and allows to reduce the form factor uncertainty of |VUS |. The NA48/2 experiment at CERN collected a very large sample of charged kaon decays into multiple final states. From this data sample we have reconstructed about 1663 events of the very rare decay K ± → μ ± νe + e - over almost negligible background in the region with m(e + e -) above 140 MeV, which is of great interest in Chiral Perturbation Theory. We present the mee spectrum and a model-independent measurement of the decay rate for this region.

Research on data from the ATLAS experiment at CERN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Purohit, Milind V.

2015-07-31

In this report senior investigator Prof. Milind V. Purohit describes research done with data from the ATLAS experiment at CERN. This includes preparing papers on the performance of the CSC detector, searches for SUSY using a new modern ''big data'' technique, and a search for supersymmetry (SUSY) using the "zero leptons razor" (0LRaz) technique. The prediction of the W=Z+jets background processes by the ATLAS simulation prior to the fit is found to be overestimated in the phase space of interest. In all new signal regions presented in this analysis the number of events observed is consistent with the post-fit SMmore » expectations. Assuming R-parity conservation, the limit on the gluino mass exceeds 1150 GeV at 95% confidence level, for an LSP mass smaller than 100 GeV. Other USC personnel who participated in this project during the period of this grant were a graduate student, Anton Kravchenko.« less

Lectures from the European RTN Winter School on Strings, Supergravity and Gauge Theories, CERN, 16 20 January, 2006

NASA Astrophysics Data System (ADS)

Derendinger, J.-P.; Scrucca, C. A.; Uranga, A. M.

2006-11-01

This special issue is devoted to the proceedings of the conference 'Winter School on Strings, Supergravity and Gauge Theories', which took place at CERN, the European Centre for Nuclear Research, in Geneva, Switzerland, from the 16 to the 20 of January 2006. This event was organized in the framework of the European Mobility Research and Training Network entitled 'Constituents, Fundamental Forces and Symmetries of the Universe'. It is part of a yearly series of scientific schools which have become a traditional rendezvous for young researchers of the community. The previous one was held at SISSA, in Trieste, Italy, in February 2005, and the next one will take place again at CERN, in January 2007. The school was primarily meant for young doctoral students and postdoctoral researchers working in the area of string theory. It consisted of five general lectures of four hours each, whose notes are published in the present proceedings, and five working group discussion sessions, focused on specific topics of the network research program. It was attended by approximately 250 participants. The topics of the lectures were chosen to provide an introduction to some of the areas of recent progress and to the open problems in string theory. String theory is expected to provide insights into the description of systems where the role of gravity is crucial. One prominent example of such systems are time-dependent backgrounds with big bang singularities, whose status in string theory is reviewed in the lecture notes by Ben Craps. In another main problem in quantum gravity, string theory gives a fascinating microscopic description of black holes and their properties. The lectures by Shiraz Minwalla review the thermal properties of black holes from their microscopic description in terms of a holographically dual large N field theory. Progress in the description of black hole microstates, and its interplay with the macroscopic description in terms of supergravity solutions via the

The beam and detector of the NA62 experiment at CERN

DOE PAGES

Gil, E. Cortina; Albarrán, E. Martín; Minucci, E.; ...

2017-05-31

NA62 is a fixed-target experiment at the CERN SPS dedicated to measurements of rare kaon decays. Such measurements, like the branching fraction of the K + → π + ν ν¯ decay, have the potential to bring significant insights into new physics processes when comparison is made with precise theoretical predictions. For this purpose, innovative techniques have been developed, in particular, in the domain of low-mass tracking devices. Detector construction spanned several years from 2009 to 2014. The collaboration started detector commissioning in 2014 and will collect data until the end of 2018. Furthermore, the beam line and detector componentsmore » are described together with their early performance obtained from 2014 and 2015 data.« less

The beam and detector of the NA62 experiment at CERN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gil, E. Cortina; Albarrán, E. Martín; Minucci, E.

NA62 is a fixed-target experiment at the CERN SPS dedicated to measurements of rare kaon decays. Such measurements, like the branching fraction of the K + → π + ν ν¯ decay, have the potential to bring significant insights into new physics processes when comparison is made with precise theoretical predictions. For this purpose, innovative techniques have been developed, in particular, in the domain of low-mass tracking devices. Detector construction spanned several years from 2009 to 2014. The collaboration started detector commissioning in 2014 and will collect data until the end of 2018. Furthermore, the beam line and detector componentsmore » are described together with their early performance obtained from 2014 and 2015 data.« less

Facilities Performance Indicators Report, 2004-05. Facilities Core Data Survey

ERIC Educational Resources Information Center

Glazner, Steve, Ed.

2006-01-01

The purpose of "Facilities Performance Indicators" is to provide a representative set of statistics about facilities in educational institutions. The second iteration of the web-based Facilities Core Data Survey was posted and available to facilities professionals at more than 3,000 institutions in the Fall of 2005. The website offered a printed…

CERN-derived analysis of lunar radiation backgrounds

NASA Technical Reports Server (NTRS)

Wilson, Thomas L.; Svoboda, Robert

1993-01-01

The Moon produces radiation which background-limits scientific experiments there. Early analyses of these backgrounds have either failed to take into consideration the effect of charm in particle physics (because they pre-dated its discovery), or have used branching ratios which are no longer strictly valid (due to new accelerator data). We are presently investigating an analytical program for deriving muon and neutrino spectra generated by the Moon, converting an existing CERN computer program known as GEANT which does the same for the Earth. In so doing, this will (1) determine an accurate prompt neutrino spectrum produced by the lunar surface; (2) determine the lunar subsurface particle flux; (3) determine the consequence of charm production physics upon the lunar background radiation environment; and (4) provide an analytical tool for the NASA astrophysics community with which to begin an assessment of the Moon as a scientific laboratory versus its particle radiation environment. This will be done on a recurring basis with the latest experimental results of the particle data groups at Earth-based high-energy accelerators, in particular with the latest branching ratios for charmed meson decay. This will be accomplished for the first time as a full 3-dimensional simulation.

[The Big Data Game : On the Ludic Constitution of the Collaborative Production of Knowledge in High-Energy Physics at CERN].

PubMed

Dippel, Anne

2017-12-01

This article looks at how games and play contribute to the big data-driven production of knowledge in High-Energy Physics, with a particular focus on the Large Hadron Collider (LHC) at the European Organization for Nuclear Research (CERN), where the author has been conducting anthropological fieldwork since 2014. The ludic (playful) aspect of knowledge production is analyzed here in three different dimensions: the Symbolic, the Ontological, and the Epistemic. The first one points towards CERN as place where a cosmological game of probability is played with the help of Monte-Carlo simulations. The second one can be seen in the agonistic infrastructures of competing experimental collaborations. The third dimension unfolds in ludic platforms, such as online Challenges and citizen science games, which contribute to the development of machine learning algorithms, whose function is necessary in order to process the huge amount of data gathered from experimental events. Following Clifford Geertz, CERN itself is characterized as a site of deep play, a concept that contributes to understanding wider social and cultural orders through the analysis of ludic collective phenomena. The article also engages with Peter Galison's idea of the trading zone, proposing to comprehend it in the age of big data as a Playground. Thus the author hopes to contribute to a wider discussion in the historiographical and social study of science and technology, as well as in cultural anthropology, by recognizing the ludic in science as a central element of understanding collaborative knowledge production.

Investigating the Inverse Square Law with the Timepix Hybrid Silicon Pixel Detector: A CERN [at] School Demonstration Experiment

ERIC Educational Resources Information Center

Whyntie, T.; Parker, B.

2013-01-01

The Timepix hybrid silicon pixel detector has been used to investigate the inverse square law of radiation from a point source as a demonstration of the CERN [at] school detector kit capabilities. The experiment described uses a Timepix detector to detect the gamma rays emitted by an [superscript 241]Am radioactive source at a number of different…

NASA Wallops Flight Facility Air-Sea Interaction Research Facility

NASA Technical Reports Server (NTRS)

Long, Steven R.

1992-01-01

This publication serves as an introduction to the Air-Sea Interaction Research Facility at NASA/GSFC/Wallops Flight Facility. The purpose of this publication is to provide background information on the research facility itself, including capabilities, available instrumentation, the types of experiments already done, ongoing experiments, and future plans.

Facilities Performance Indicators Report 2012-13: Tracking Your Facilities Vital Signs

ERIC Educational Resources Information Center

APPA: Association of Higher Education Facilities Officers, 2014

2014-01-01

This paper features an expanded Web-based "Facilities Performance Indicators (FPI) Report." The purpose of APPA's Facilities Performance Indicators is to provide a representative set of statistics about facilities in educational institutions. "The Facilities Performance Indicators Report" is designed for survey…

Planning and Designing Facilities. Facility Design and Development--Part 1

ERIC Educational Resources Information Center

Hypes, Michael G.

2006-01-01

Before one begins the planning process for a new facility, it is important to determine if there is a need for a new facility. The demand for a new facility can be drawn from increases in the number of users, the type of users, and the type of events to be conducted in the facility. A feasibility study should be conducted to analyze the legal…

Future carbon beams at SPIRAL1 facility: Which method is the most efficient?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maunoury, L., E-mail: maunoury@ganil.fr; Delahaye, P.; Dubois, M.

2014-02-15

Compared to in-flight facilities, Isotope Separator On-Line ones can in principle produce significantly higher radioactive ion beam intensities. On the other hand, they have to cope with delays for the release and ionization which make the production of short-lived isotopes ion beams of reactive and refractory elements particularly difficult. Many efforts are focused on extending the capabilities of ISOL facilities to those challenging beams. In this context, the development of carbon beams is triggering interest [H. Frånberg, M. Ammann, H. W. Gäggeler, and U. Köster, Rev. Sci. Instrum. 77, 03A708 (2006); M. Kronberger, A. Gottberg, T. M. Mendonca, J. P.more » Ramos, C. Seiffert, P. Suominen, and T. Stora, in Proceedings of the EMIS 2012 [Nucl. Instrum. Methods Phys. Res. B Production of molecular sideband radioisotope beams at CERN-ISOLDE using a Helicon-type plasma ion source (to be published)]: despite its refractory nature, radioactive carbon beams can be produced from molecules (CO or CO{sub 2}), which can subsequently be broken up and multi-ionized to the required charge state in charge breeders or ECR sources. This contribution will present results of experiments conducted at LPSC with the Phoenix charge breeder and at GANIL with the Nanogan ECR ion source for the ionization of carbon beams in the frame of the ENSAR and EMILIE projects. Carbon is to date the lightest condensable element charge bred with an ECR ion source. Charge breeding efficiencies will be compared with those obtained using Nanogan ECRIS and charge breeding times will be presented as well.« less

18. Topside facility, interior of facility manager's room, view towards ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

18. Topside facility, interior of facility manager's room, view towards west. Lyon - Whiteman Air Force Base, Oscar O-1 Minuteman Missile Alert Facility, Southeast corner of Twelfth & Vendenberg Avenues, Knob Noster, Johnson County, MO

Experimental Fuels Facility Re-categorization Based on Facility Segmentation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reiss, Troy P.; Andrus, Jason

The Experimental Fuels Facility (EFF) (MFC-794) at the Materials and Fuels Complex (MFC) located on the Idaho National Laboratory (INL) Site was originally constructed to provide controlled-access, indoor storage for radiological contaminated equipment. Use of the facility was expanded to provide a controlled environment for repairing contaminated equipment and characterizing, repackaging, and treating waste. The EFF facility is also used for research and development services, including fuel fabrication. EFF was originally categorized as a LTHC-3 radiological facility based on facility operations and facility radiological inventories. Newly planned program activities identified the need to receive quantities of fissionable materials in excessmore » of the single parameter subcritical limit in ANSI/ANS-8.1, “Nuclear Criticality Safety in Operations with Fissionable Materials Outside Reactors” (identified as “criticality list” quantities in DOE-STD-1027-92, “Hazard Categorization and Accident Analysis Techniques for Compliance with DOE Order 5480.23, Nuclear Safety Analysis Reports,” Attachment 1, Table A.1). Since the proposed inventory of fissionable materials inside EFF may be greater than the single parameter sub-critical limit of 700 g of U-235 equivalent, the initial re-categorization is Hazard Category (HC) 2 based upon a potential criticality hazard. This paper details the facility hazard categorization performed for the EFF. The categorization was necessary to determine (a) the need for further safety analysis in accordance with LWP-10802, “INL Facility Categorization,” and (b) compliance with 10 Code of Federal Regulations (CFR) 830, Subpart B, “Safety Basis Requirements.” Based on the segmentation argument presented in this paper, the final hazard categorization for the facility is LTHC-3. Department of Energy Idaho (DOE-ID) approval of the final hazard categorization determined by this hazard assessment document (HAD) was required

Cryogenic test facility instrumentation with fiber optic and fiber optic sensors for testing superconducting accelerator magnets

NASA Astrophysics Data System (ADS)

Chiuchiolo, A.; Bajas, H.; Bajko, M.; Castaldo, B.; Consales, M.; Cusano, A.; Giordano, M.; Giloux, C.; Perez, J. C.; Sansone, L.; Viret, P.

2017-12-01

The magnets for the next steps in accelerator physics, such as the High Luminosity upgrade of the LHC (HL- LHC) and the Future Circular Collider (FCC), require the development of new technologies for manufacturing and monitoring. To meet the HL-LHC new requirements, a large upgrade of the CERN SM18 cryogenic test facilities is ongoing with the implementation of new cryostats and cryogenic instrumentation. The paper deals with the advances in the development and the calibration of fiber optic sensors in the range 300 - 4 K using a dedicated closed-cycle refrigerator system composed of a pulse tube and a cryogen-free cryostat. The calibrated fiber optic sensors (FOS) have been installed in three vertical cryostats used for testing superconducting magnets down to 1.9 K or 4.2 K and in the variable temperature test bench (100 - 4.2 K). Some examples of FOS measurements of cryostat temperature evolution are presented as well as measurements of strain performed on a subscale of High Temperature Superconducting magnet during its powering tests.

First test of BNL electron beam ion source with high current density electron beam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pikin, Alexander, E-mail: pikin@bnl.gov; Alessi, James G., E-mail: pikin@bnl.gov; Beebe, Edward N., E-mail: pikin@bnl.gov

A new electron gun with electrostatic compression has been installed at the Electron Beam Ion Source (EBIS) Test Stand at BNL. This is a collaborative effort by BNL and CERN teams with a common goal to study an EBIS with electron beam current up to 10 A, current density up to 10,000 A/cm{sup 2} and energy more than 50 keV. Intensive and pure beams of heavy highly charged ions with mass-to-charge ratio < 4.5 are requested by many heavy ion research facilities including NASA Space Radiation Laboratory (NSRL) at BNL and HIE-ISOLDE at CERN. With a multiampere electron gun, themore » EBIS should be capable of delivering highly charged ions for both RHIC facility applications at BNL and for ISOLDE experiments at CERN. Details of the electron gun simulations and design, and the Test EBIS electrostatic and magnetostatic structures with the new electron gun are presented. The experimental results of the electron beam transmission are given.« less

Ageing Studies on the First Resistive-MicroMeGaS Quadruplet at GIF++ Preliminary Results

NASA Astrophysics Data System (ADS)

Alvarez Gonzalez, B.; Bianco, M.; Farina, E.; Iengo, P.; Kuger, F.; Lin, T.; Longo, L.; Sekhniaidze, G.; Sidiropoulou, O.; Schott, M.; Valderanis, C.; Wotschack, J.

2018-02-01

A resistive-MicroMeGaS quadruplet built at CERN has been installed at the new CERN Gamma Irradiation Facility (GIF++) with the aim of carrying out a long-term ageing study. Two smaller resistive bulk-MicroMeGaS produced at the CERN PCB workshop have also been installed at GIF++ in order to provide a comparison of the ageing behavior with the MicroMeGaS quadruplet. We give an overview of the ongoing tests at GIF++ in terms of particle rate, integrated charge and spatial resolution of the MicroMeGaS detectors.

Characterization of extended range Bonner Sphere Spectrometers in the CERF high-energy broad neutron field at CERN

NASA Astrophysics Data System (ADS)

Agosteo, S.; Bedogni, R.; Caresana, M.; Charitonidis, N.; Chiti, M.; Esposito, A.; Ferrarini, M.; Severino, C.; Silari, M.

2012-12-01

controlled workplace field. The CERF (CERN-EU high-energy reference field) facility is a unique example of such a field, where a number of experimental campaigns and Monte Carlo simulations have been performed over the past years. With the aim of performing this kind of workplace performance test, four different ERBSS with different degrees of validation, operated by three groups (CERN, INFN-LNF and Politecnico of Milano), were exposed in two fixed positions at CERF. Using different unfolding codes (MAXED, GRAVEL, FRUIT and FRUIT SGM), the experimental data were analyzed to provide the neutron spectra and the related dosimetric quantities. The results allow assessing the overall performance of each ERBSS and of the unfolding codes, as well as comparing the performance of three ERRCs when used in a neutron field with energy distribution different from the calibration spectrum.

Hanford Facility dangerous waste permit application, liquid effluent retention facility and 200 area effluent treatment facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coenenberg, J.G.

1997-08-15

The Hanford Facility Dangerous Waste Permit Application is considered to 10 be a single application organized into a General Information Portion (document 11 number DOE/RL-91-28) and a Unit-Specific Portion. The scope of the 12 Unit-Specific Portion is limited to Part B permit application documentation 13 submitted for individual, `operating` treatment, storage, and/or disposal 14 units, such as the Liquid Effluent Retention Facility and 200 Area Effluent 15 Treatment Facility (this document, DOE/RL-97-03). 16 17 Both the General Information and Unit-Specific portions of the Hanford 18 Facility Dangerous Waste Permit Application address the content of the Part B 19 permit applicationmore » guidance prepared by the Washington State Department of 20 Ecology (Ecology 1987 and 1996) and the U.S. Environmental Protection Agency 21 (40 Code of Federal Regulations 270), with additional information needs 22 defined by the Hazardous and Solid Waste Amendments and revisions of 23 Washington Administrative Code 173-303. For ease of reference, the Washington 24 State Department of Ecology alpha-numeric section identifiers from the permit 25 application guidance documentation (Ecology 1996) follow, in brackets, the 26 chapter headings and subheadings. A checklist indicating where information is 27 contained in the Liquid Effluent Retention Facility and 200 Area Effluent 28 Treatment Facility permit application documentation, in relation to the 29 Washington State Department of Ecology guidance, is located in the Contents 30 Section. 31 32 Documentation contained in the General Information Portion is broader in 33 nature and could be used by multiple treatment, storage, and/or disposal units 34 (e.g., the glossary provided in the General Information Portion). Wherever 35 appropriate, the Liquid Effluent Retention Facility and 200 Area Effluent 36 Treatment Facility permit application documentation makes cross-reference to 37 the General Information Portion, rather than

KTAG: The Kaon Identification Detector for CERN experiment NA62

NASA Astrophysics Data System (ADS)

Fry, J. R.; CERN NA62 Collaboration

2016-07-01

In the study of ultra-rare kaon decays, CERN experiment NA62 exploits an unseparated monochromatic (75 GeV/c) beam of charged particles of flux 800 MHz, of which 50 MHz are K+. Kaons are identified with more than 95% efficiency, a time resolution of better than 100 ps, and misidentification of less than 10-4 using KTAG, a differential, ring-focussed, Cherenkov detector. KTAG utilises 8 sets of 48 Hamamatsu PMTs, of which 32 are of type 9880 and 16 of type 7400, with signals fed directly to the differential inputs of NINO front-end boards and then to TDC cards within the TEL62 system. Leading and trailing edges of the PMT signal are digitised, enabling slewing corrections to be made, and a mean hit rate of 5 MHz per PMT is supported. The electronics is housed within a cooled and insulated Faraday cage with environmental monitoring capabilities.

FACILITY 846, SOUTHEAST END ON LEFT, WITH FACILITY 845 ON ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

FACILITY 846, SOUTHEAST END ON LEFT, WITH FACILITY 845 ON RIGHT AND FACILITY 847 IN CENTER BACKGROUND, QUADRANGLE J, VIEW FACING NORTH. - Schofield Barracks Military Reservation, Quadrangles I & J Barracks Type, Between Wright-Smith & Capron Avenues near Williston Avenue, Wahiawa, Honolulu County, HI

About Separation of Hadron and Electromagnetic Cascades in the Pamela Calorimeter

NASA Astrophysics Data System (ADS)

Stozhkov, Yuri I.; Basili, A.; Bencardino, R.; Casolino, M.; de Pascale, M. P.; Furano, G.; Menicucci, A.; Minori, M.; Morselli, A.; Picozza, P.; Sparvoli, R.; Wischnewski, R.; Bakaldin, A.; Galper, A. M.; Koldashov, S. V.; Korotkov, M. G.; Mikhailov, V. V.; Voronov, S. A.; Yurkin, Y. T.; Adriani, O.; Bonechi, L.; Bongi, M.; Papini, P.; Ricciarini, S. B.; Spillantini, P.; Straulino, S.; Taccetti, F.; Vannuccini, E.; Castellini, G.; Boezio, M.; Bonvicini, M.; Mocchiutti, E.; Schiavon, P.; Vacchi, A.; Zampa, G.; Zampa, N.; Carlson, P.; Lund, J.; Lundquist, J.; Orsi, S.; Pearce, M.; Barbarino, G. C.; Campana, D.; Osteria, G.; Rossi, G.; Russo, S.; Boscherini, M.; Mennh, W.; Simonh, M.; Bongiorno, L.; Ricci, M.; Ambriola, M.; Bellotti, R.; Cafagna, F.; Circella, M.; de Marzo, C.; Giglietto, N.; Mirizzi, N.; Romita, M.; Spinelli, P.; Bogomolov, E.; Krutkov, S.; Vasiljev, G.; Bazilevskaya, G. A.; Kvashnin, A. N.; Logachev, V. I.; Makhmutov, V. S.; Maksumov, O. S.; Stozhkov, Yu. I.; Mitchell, J. W.; Streitmatter, R. E.; Stochaj, S. J.

Results of calibration of the PAMELA instrument at the CERN facilities are discussed. In September, 2003, the calibration of the Neutron Detector together with the Calorimeter was performed with the CERN beams of electrons and protons with energies of 20 - 180 GeV. The implementation of the Neutron Detector increases a rejection factor of hadrons from electrons about ten times. The results of calibration are in agreement with calculations.

Facilities | Bioenergy | NREL

Science.gov Websites

Facilities Facilities At NREL's state-of-the-art bioenergy research facilities, researchers design options. Photo of interior of industrial, two-story building with high-bay, piping, and large processing

EPA Facility Registry Service (FRS): Facility Interests Dataset

EPA Pesticide Factsheets

This web feature service consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in the FRS individual feature layers. The layers comprise the FRS major program databases, including:Assessment Cleanup and Redevelopment Exchange System (ACRES) : brownfields sites ; Air Facility System (AFS) : stationary sources of air pollution ; Air Quality System (AQS) : ambient air pollution data from monitoring stations; Bureau of Indian Affairs (BIA) : schools data on Indian land; Base Realignment and Closure (BRAC) facilities; Clean Air Markets Division Business System (CAMDBS) : market-based air pollution control programs; Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) : hazardous waste sites; Integrated Compliance Information System (ICIS) : integrated enforcement and compliance information; National Compliance Database (NCDB) : Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Toxic Substances Control Act (TSCA); National Pollutant Discharge Elimination System (NPDES) module of ICIS : NPDES surface water permits; Radiation Information Database (RADINFO) : radiation and radioactivity facilities; RACT/BACT/LAER Clearinghouse (RBLC) : best available air pollution technology requirements; Resource Conservation and Recovery Act Information System (RCRAInfo) : tracks generators, transporters, treaters, storers, and disposers of haz

ALICE inner tracking system readout electronics prototype testing with the CERN "Giga Bit Transceiver''

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schambach, Joachim; Rossewij, M. J.; Sielewicz, K. M.

The ALICE Collaboration is preparing a major detector upgrade for the LHC Run 3, which includes the construction of a new silicon pixel based Inner Tracking System (ITS). The ITS readout system consists of 192 readout boards to control the sensors and their power system, receive triggers, and deliver sensor data to the DAQ. To prototype various aspects of this readout system, an FPGA based carrier board and an associated FMC daughter card containing the CERN Gigabit Transceiver (GBT) chipset have been developed. Furthermore, this contribution describes laboratory and radiation testing results with this prototype board set.

ALICE inner tracking system readout electronics prototype testing with the CERN "Giga Bit Transceiver''

DOE PAGES

Schambach, Joachim; Rossewij, M. J.; Sielewicz, K. M.; ...

2016-12-28

The ALICE Collaboration is preparing a major detector upgrade for the LHC Run 3, which includes the construction of a new silicon pixel based Inner Tracking System (ITS). The ITS readout system consists of 192 readout boards to control the sensors and their power system, receive triggers, and deliver sensor data to the DAQ. To prototype various aspects of this readout system, an FPGA based carrier board and an associated FMC daughter card containing the CERN Gigabit Transceiver (GBT) chipset have been developed. Furthermore, this contribution describes laboratory and radiation testing results with this prototype board set.

ALICE inner tracking system readout electronics prototype testing with the CERN ``Giga Bit Transceiver''

NASA Astrophysics Data System (ADS)

Schambach, J.; Rossewij, M. J.; Sielewicz, K. M.; Aglieri Rinella, G.; Bonora, M.; Ferencei, J.; Giubilato, P.; Vanat, T.

2016-12-01

The ALICE Collaboration is preparing a major detector upgrade for the LHC Run 3, which includes the construction of a new silicon pixel based Inner Tracking System (ITS). The ITS readout system consists of 192 readout boards to control the sensors and their power system, receive triggers, and deliver sensor data to the DAQ. To prototype various aspects of this readout system, an FPGA based carrier board and an associated FMC daughter card containing the CERN Gigabit Transceiver (GBT) chipset have been developed. This contribution describes laboratory and radiation testing results with this prototype board set.

Can Intestinal Phosphate Binding or Inhibition of Hydroxyapatite Growth in the Vascular Wall Halt the Progression of Established Aortic Calcification in Chronic Kidney Disease?

PubMed

Neven, Ellen; Opdebeeck, Britt; De Maré, Annelies; Bashir-Dar, Rida; Dams, Geert; Marynissen, Rita; Behets, Geert J; Verhulst, Anja; Riser, Bruce L; D'Haese, Patrick C

2016-11-01

Vascular calcification significantly contributes to mortality in chronic kidney disease (CKD) patients. Sevelamer and pyrophosphate (PPi) have proven to be effective in preventing vascular calcification, the former by controlling intestinal phosphate absorption, the latter by directly interfering with the hydroxyapatite crystal formation. Since most patients present with established vascular calcification, it is important to evaluate whether these compounds may also halt or reverse the progression of preexisting vascular calcification. CKD and vascular calcification were induced in male Wistar rats by a 0.75 % adenine low protein diet for 4 weeks. Treatment with PPi (30 or 120 µmol/kg/day), sevelamer carbonate (1500 mg/kg/day) or vehicle was started at the time point at which vascular calcification was present and continued for 3 weeks. Hyperphosphatemia and vascular calcification developed prior to treatment. A significant progression of aortic calcification in vehicle-treated rats with CKD was observed over the final 3-week period. Sevelamer treatment significantly reduced further progression of aortic calcification as compared to the vehicle control. No such an effect was seen for either PPi dose. Sevelamer but not PPi treatment resulted in an increase in both osteoblast and osteoid perimeter. Our study shows that sevelamer was able to reduce the progression of moderate to severe preexisting aortic calcification in a CKD rat model. Higher doses of PPi may be required to induce a similar reduction of severe established arterial calcification in this CKD model.

Study of muon-induced neutron production using accelerator muon beam at CERN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nakajima, Y.; Lin, C. J.; Ochoa-Ricoux, J. P.

2015-08-17

Cosmogenic muon-induced neutrons are one of the most problematic backgrounds for various underground experiments for rare event searches. In order to accurately understand such backgrounds, experimental data with high-statistics and well-controlled systematics is essential. We performed a test experiment to measure muon-induced neutron production yield and energy spectrum using a high-energy accelerator muon beam at CERN. We successfully observed neutrons from 160 GeV/c muon interaction on lead, and measured kinetic energy distributions for various production angles. Works towards evaluation of absolute neutron production yield is underway. This work also demonstrates that the setup is feasible for a future large-scale experimentmore » for more comprehensive study of muon-induced neutron production.« less

Alpha linolenic acid in maternal diet halts the lipid disarray due to saturated fatty acids in the liver of mice offspring at weaning.

PubMed

Shomonov-Wagner, Limor; Raz, Amiram; Leikin-Frenkel, Alicia

2015-02-26

Alpha linolenic acid (ALA, 18:3) in maternal diets has been shown to attenuate obesity associated insulin resistance (IR) in adult offspring in mice. The objective in the present study was to detect the early effects of maternal dietary saturated fatty acids (SFA) and their partial substitution with ω-3 ALA, docosa hexenoic acid (DHA,22:6) and eicosapentenoic acid 20:5 (EPA,20:5) on the HOMA index, liver lipids and fatty acid desaturases in the offspring at weaning. 3 month old C57Bl6/J female mice were fed diets containing normal amount of calories but rich in SFA alone or partially replaced with ALA, DHA or EPA before mating, during pregnancy and lactation. Pregnant mice fed SFA produced offspring with the highest HOMA index, liver lipids and desaturase activities. ALA prevented SFA induced lipid increase but DHA and EPA only reduced it by 42% and 31% respectively. ALA, DHA and EPA decreased HOMA index by 84%, 75% and 83% respectively. ALA, DHA and EPA decreased Δ6 and SCD1 desaturase activities about 30%. SFA feeding to mothers predisposes their offspring to develop IR and liver lipid accumulation already at weaning. ω3 fatty acids reduce IR, ALA halts lipid accumulation whereas DHA and EPA only blunt it.ALA and DHA restore the increased SCD1 to normal. These studies suggest that ω-3 fatty acids have different potencies to preclude lipid accumulation in the offspring partially by affecting pathways associated to SCD1 modulation.

Radioactive ion beams at ISOLDE/CERN recent developments and perspectives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Georg, U.; Catherall, R.; Giles, T.

1999-11-16

Since the move of ISOLDE from CERN's synchrocyclotron (SC) to the Proton Synchrotron Booster (PSB) in 1992 extensive work has been devoted to the development of new beams, i.e. the production of new isotopes, beams of higher intensity and the ionization of further elements. Most of these developments were driven by the particular needs of the physics community proposing new experiments. The main achievements were the adaption of liquid metal targets to the pulsed proton beam to prevent shockwaves and splashing inside the target container and systematic studies on the time structure of the release of the isotopes from themore » target. Furthermore the work on laser ion-sources already started at ISOLDE-2 was continued, the so-called RIST target was developed, and most recently first tests on the isotope production while increasing the proton energy from 1 GeV to 1.4 GeV were done. The latter topics are discussed in this paper.« less

Radioactive Ion Beams at ISOLDE/CERN Recent Developments and Perspectives

DOE Office of Scientific and Technical Information (OSTI.GOV)

U. Georg; J.R.J. Bennett; U.C. Bergmann

1999-12-31

Since the move of ISOLDE from CERN's synchrocyclotron (SC) to the Proton Synchrotron Booster (PSB) in 1992 extensive work has been devoted to the development of new beams, i.e. the production of new isotopes, beams of higher intensity and the ionization of further elements. Most of these developments were driven by the particular needs of the physics community proposing new experiments. The main achievements were the adaption of liquid metal targets to the pulsed proton beam to prevent shockwaves and splashing inside the target container and systematic studies on the time structure of the release of the isotopes from themore » target. Furthermore the work on laser ion-sources already started at ISOLDE-2 was continued, the so-called RIST target was developed, and most recently first tests on the isotope production while increasing the proton energy from 1 GeV to 1.4 GeV were done. The latter topics are discussed in this paper.« less

Research and test facilities

NASA Technical Reports Server (NTRS)

1993-01-01

A description is given of each of the following Langley research and test facilities: 0.3-Meter Transonic Cryogenic Tunnel, 7-by 10-Foot High Speed Tunnel, 8-Foot Transonic Pressure Tunnel, 13-Inch Magnetic Suspension & Balance System, 14-by 22-Foot Subsonic Tunnel, 16-Foot Transonic Tunnel, 16-by 24-Inch Water Tunnel, 20-Foot Vertical Spin Tunnel, 30-by 60-Foot Wind Tunnel, Advanced Civil Transport Simulator (ACTS), Advanced Technology Research Laboratory, Aerospace Controls Research Laboratory (ACRL), Aerothermal Loads Complex, Aircraft Landing Dynamics Facility (ALDF), Avionics Integration Research Laboratory, Basic Aerodynamics Research Tunnel (BART), Compact Range Test Facility, Differential Maneuvering Simulator (DMS), Enhanced/Synthetic Vision & Spatial Displays Laboratory, Experimental Test Range (ETR) Flight Research Facility, General Aviation Simulator (GAS), High Intensity Radiated Fields Facility, Human Engineering Methods Laboratory, Hypersonic Facilities Complex, Impact Dynamics Research Facility, Jet Noise Laboratory & Anechoic Jet Facility, Light Alloy Laboratory, Low Frequency Antenna Test Facility, Low Turbulence Pressure Tunnel, Mechanics of Metals Laboratory, National Transonic Facility (NTF), NDE Research Laboratory, Polymers & Composites Laboratory, Pyrotechnic Test Facility, Quiet Flow Facility, Robotics Facilities, Scientific Visualization System, Scramjet Test Complex, Space Materials Research Laboratory, Space Simulation & Environmental Test Complex, Structural Dynamics Research Laboratory, Structural Dynamics Test Beds, Structures & Materials Research Laboratory, Supersonic Low Disturbance Pilot Tunnel, Thermal Acoustic Fatigue Apparatus (TAFA), Transonic Dynamics Tunnel (TDT), Transport Systems Research Vehicle, Unitary Plan Wind Tunnel, and the Visual Motion Simulator (VMS).

First results from a combined analysis of CERN computing infrastructure metrics

NASA Astrophysics Data System (ADS)

Duellmann, Dirk; Nieke, Christian

2017-10-01

The IT Analysis Working Group (AWG) has been formed at CERN across individual computing units and the experiments to attempt a cross cutting analysis of computing infrastructure and application metrics. In this presentation we will describe the first results obtained using medium/long term data (1 months — 1 year) correlating box level metrics, job level metrics from LSF and HTCondor, IO metrics from the physics analysis disk pools (EOS) and networking and application level metrics from the experiment dashboards. We will cover in particular the measurement of hardware performance and prediction of job duration, the latency sensitivity of different job types and a search for bottlenecks with the production job mix in the current infrastructure. The presentation will conclude with the proposal of a small set of metrics to simplify drawing conclusions also in the more constrained environment of public cloud deployments.

30 CFR 71.400 - Bathing facilities; change rooms; sanitary flush toilet facilities.

Code of Federal Regulations, 2012 CFR

2012-07-01

... WORK AREAS OF UNDERGROUND COAL MINES Surface Bathing Facilities, Change Rooms, and Sanitary Flush Toilet Facilities at Surface Coal Mines § 71.400 Bathing facilities; change rooms; sanitary flush toilet... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Bathing facilities; change rooms; sanitary...

30 CFR 71.400 - Bathing facilities; change rooms; sanitary flush toilet facilities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... WORK AREAS OF UNDERGROUND COAL MINES Surface Bathing Facilities, Change Rooms, and Sanitary Flush Toilet Facilities at Surface Coal Mines § 71.400 Bathing facilities; change rooms; sanitary flush toilet... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Bathing facilities; change rooms; sanitary...

30 CFR 71.400 - Bathing facilities; change rooms; sanitary flush toilet facilities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... WORK AREAS OF UNDERGROUND COAL MINES Surface Bathing Facilities, Change Rooms, and Sanitary Flush Toilet Facilities at Surface Coal Mines § 71.400 Bathing facilities; change rooms; sanitary flush toilet... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Bathing facilities; change rooms; sanitary...

30 CFR 71.400 - Bathing facilities; change rooms; sanitary flush toilet facilities.

Code of Federal Regulations, 2011 CFR

2011-07-01

... WORK AREAS OF UNDERGROUND COAL MINES Surface Bathing Facilities, Change Rooms, and Sanitary Flush Toilet Facilities at Surface Coal Mines § 71.400 Bathing facilities; change rooms; sanitary flush toilet... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Bathing facilities; change rooms; sanitary...

The AMS-02 RICH detector: Performance during ground-based data taking at CERN

NASA Astrophysics Data System (ADS)

Pereira, R.; AMS RICH Collaboration

2011-05-01

The Alpha Magnetic Spectrometer (AMS), whose final version AMS-02 is to be installed on the International Space Station (ISS) in 2011, is a detector designed to measure charged cosmic ray spectra with energies up to the TeV region and with high energy photon detection capability up to a few hundred GeV, using state-of-the art particle identification techniques. Among several detector subsystems, AMS includes a proximity focusing RICH detector enabling precise measurements of particle electric charge (charge identification up to the iron region) and velocity ( Δβ/β˜10-3 for Z=1, Δβ/β˜10-4 for Z=10-20). The optimization of the RICH reconstruction efficiency imposed a dual radiator configuration with 16 NaF tiles ( n=1.33) in the centre and 92 aerogel tiles ( n=1.050) in the outer region, a pixelized detection matrix with 680 Hamamatsu R7600-M16 photomultipliers (each with 4×4 pixels) and a highly reflective conical mirror to increase photon collection. After its assembly at CIEMAT in Madrid, the RICH was taken to CERN in January 2008 and integrated into the full AMS-02 detector. AMS-02 underwent a pre-assembly in 2008 without magnet followed by a second detector assembly with a superconducting magnet in 2009 and the final assembly with a permanent magnet in mid-2010. Cosmic events were acquired in the context of the 2008 pre-assembly and in 2009, and two beam tests from CERN SPS took place in 2010. Results obtained with data from ground-based tests on the RICH performance are presented. A comparison with the aerogel light yield obtained on previous beam tests with a prototype detector is also discussed.

Indoor Athletic Facilities.

ERIC Educational Resources Information Center

Fleming, E. Scott

2000-01-01

Examines the concept of shared-use facilities to help financially support and meet the demand for athletic facilities. Shared-use considerations are explored including cost sharing of ongoing operations, aesthetics, locker rooms, support facilities, parking and site access, and building access and security. (GR)

Aircraft Landing Dynamics Facility - A unique facility with new capabilities

NASA Technical Reports Server (NTRS)

Davis, P. A.; Stubbs, S. M.; Tanner, J. A.

1985-01-01

The Aircraft Landing Dynamics Facility (ALDF), formerly called the Landing Loads Track, is described. The paper gives a historical overview of the original NASA Langley Research Center Landing Loads Track and discusses the unique features of this national test facility. Comparisons are made between the original track characteristics and the new capabilities of the Aircraft Landing Dynamics Facility following the recently completed facility update. Details of the new propulsion and arresting gear systems are presented along with the novel features of the new high-speed carriage. The data acquisition system is described and the paper concludes with a review of future test programs.

EPA Facility Registry Service (FRS): Facility Interests Dataset Download

EPA Pesticide Factsheets

This downloadable data package consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in the FRS individual feature layers. The layers comprise the FRS major program databases, including:Assessment Cleanup and Redevelopment Exchange System (ACRES) : brownfields sites ; Air Facility System (AFS) : stationary sources of air pollution ; Air Quality System (AQS) : ambient air pollution data from monitoring stations; Bureau of Indian Affairs (BIA) : schools data on Indian land; Base Realignment and Closure (BRAC) facilities; Clean Air Markets Division Business System (CAMDBS) : market-based air pollution control programs; Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) : hazardous waste sites; Integrated Compliance Information System (ICIS) : integrated enforcement and compliance information; National Compliance Database (NCDB) : Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Toxic Substances Control Act (TSCA); National Pollutant Discharge Elimination System (NPDES) module of ICIS : NPDES surface water permits; Radiation Information Database (RADINFO) : radiation and radioactivity facilities; RACT/BACT/LAER Clearinghouse (RBLC) : best available air pollution technology requirements; Resource Conservation and Recovery Act Information System (RCRAInfo) : tracks generators, transporters, treaters, storers, and disposers

The High Energy cosmic-Radiation Detection (HERD) Facility onboard China's Future Space Station

NASA Astrophysics Data System (ADS)

Wu, Bobing

2015-08-01

The High Energy cosmic-Radiation Detection (HERD) facility is one of several space astronomy payloads of the cosmic lighthouse program onboard China's Space Station, which is planned for operation starting around 2020 for about 10 years. The main scientific objectives of HERD are indirect dark matter search, precise cosmic ray spectrum and composition measurements up to the knee energy, and high energy gamma-ray monitoring and survey. HERD is composed of a 3-D cubic calorimeter (CALO) surrounded by microstrip silicon trackers (STKs)from five sides except the bottom. CALO is made of about 10^4 cubes of LYSO crystals, corresponding to about 55 radiation lengths and 3 nuclear interaction lengths, respectively. HERD can achieve the following performance: energy resolution of 1% for electrons and gamma-rays beyond 100 GeV, 20% for protons from 100 GeV to 1 PeV; 2) electron/proton separation power better than 10^5 ; effective geometrical factors of > 3 m^2 sr for electron and diffuse gamma-rays, > 2 m^2 sr for cosmic ray nuclei. The prototype of about 1/40 of HERD calorimeter is under construction. A beam test in CERN with the prototype is approved and will be carried out in Nov. 2015.

Health Facilities

MedlinePlus

Health facilities are places that provide health care. They include hospitals, clinics, outpatient care centers, and specialized care centers, ... psychiatric care centers. When you choose a health facility, you might want to consider How close it ...

Aeronautical facilities assessment

NASA Technical Reports Server (NTRS)

Penaranda, F. E. (Compiler)

1985-01-01

A survey of the free world's aeronautical facilities was undertaken and an evaluation made on where the relative strengths and weaknesses exist. Special emphasis is given to NASA's own capabilities and needs. The types of facilities surveyed are: Wind Tunnels; Airbreathing Propulsion Facilities; and Flight Simulators

Section Editors

NASA Astrophysics Data System (ADS)

Groep, D. L.; Bonacorsi, D.

2014-06-01

1. Data Acquisition, Trigger and Controls Niko NeufeldCERNniko.neufeld@cern.ch Tassos BeliasDemokritosbelias@inp.demokritos.gr Andrew NormanFNALanorman@fnal.gov Vivian O'DellFNALodell@fnal.gov 2. Event Processing, Simulation and Analysis Rolf SeusterTRIUMFseuster@cern.ch Florian UhligGSIf.uhlig@gsi.de Lorenzo MonetaCERNLorenzo.Moneta@cern.ch Pete ElmerPrincetonpeter.elmer@cern.ch 3. Distributed Processing and Data Handling Nurcan OzturkU Texas Arlingtonnurcan@uta.edu Stefan RoiserCERNstefan.roiser@cern.ch Robert IllingworthFNAL Davide SalomoniINFN CNAFDavide.Salomoni@cnaf.infn.it Jeff TemplonNikheftemplon@nikhef.nl 4. Data Stores, Data Bases, and Storage Systems David LangeLLNLlange6@llnl.gov Wahid BhimjiU Edinburghwbhimji@staffmail.ed.ac.uk Dario BarberisGenovaDario.Barberis@cern.ch Patrick FuhrmannDESYpatrick.fuhrmann@desy.de Igor MandrichenkoFNALivm@fnal.gov Mark van de SandenSURF SARA sanden@sara.nl 5. Software Engineering, Parallelism & Multi-Core Solveig AlbrandLPSC/IN2P3solveig.albrand@lpsc.in2p3.fr Francesco GiacominiINFN CNAFfrancesco.giacomini@cnaf.infn.it Liz SextonFNALsexton@fnal.gov Benedikt HegnerCERNbenedikt.hegner@cern.ch Simon PattonLBNLSJPatton@lbl.gov Jim KowalkowskiFNAL jbk@fnal.gov 6. Facilities, Infrastructures, Networking and Collaborative Tools Maria GironeCERNMaria.Girone@cern.ch Ian CollierSTFC RALian.collier@stfc.ac.uk Burt HolzmanFNALburt@fnal.gov Brian Bockelman U Nebraskabbockelm@cse.unl.edu Alessandro de SalvoRoma 1Alessandro.DeSalvo@ROMA1.INFN.IT Helge MeinhardCERN Helge.Meinhard@cern.ch Ray PasetesFNAL rayp@fnal.gov Steven GoldfarbU Michigan Steven.Goldfarb@cern.ch

Patient Care Staffing Levels and Facility Characteristics in U.S. Hemodialysis Facilities

PubMed Central

Yoder, Laura A. G.; Xin, Wenjun; Norris, Keith C.; Yan, Guofen

2013-01-01

Background Higher numbers of registered nurses per patient have been associated with improved patient outcomes in acute care facilities. Variation and associations of patient-care staffing levels and hemodialysis facility characteristics have not been previously examined. Study Design Cross-sectional study using Poisson regression to examine associations betwee patient-care staffing levels and hemodialysis facility characteristics. Setting & Participants 4,800 U.S. hemodialysis facilities in the 2009 CMS ESRD Annual Facility Survey (CMS-2744), USRDS. Predictors Facility characteristics, including profit status, freestanding status, chain affiliatio and geographic region, adjusted for facility size, capacity, functional type, and urbanicity. Outcomes Patient care staffing levels, including ratios of Registered Nurses (RN), Licensed Practical Nurses (LPN), Patient Care Technicians (PCT), composite staff (RN+LPN+PCT), Social Workers, and Dietitians to in-center hemodialysis patients. Results After adjusting for background facility characteristics, the ratios of RNs and LPNs to patients were 35% (p<0.001) and 42% (p<0.001) lower, but the PCT-to-patient ratio was 16% (p<0.001) higher in for-profit facilities than those in nonprofit facilities (Rate ratio, 0.65, 95%CI, 0.63–0.68; 0.58, 0.51–0.65; 1.16, 1.12–1.19; respectively). Regionally, compared to the Northeast, the adjusted RN-to-patient ratio was 14% (p< 0.001) lower in the Midwest, 25% (p< 0.001) lower in the South, and 18% (p< 0.001) lower in the West. Even after additional adjustments, the large for-profit chains had significantly lower RN and LPN ratios than the largest nonprofit chain, but a significantly higher PCT-to-patient ratio. The overall composite staffing levels were also lower in for-profit and chain-affiliated facilities. The patterns hold when the hospital-based units were excluded. Limitations Nursing hours were not available. Conclusions The significant variation in patient-care staffing

78 FR 69468 - Self-Regulatory Organizations; Miami International Securities Exchange LLC; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-19

... option class (a ``Post-Halt Notification'') following a regulatory halt, trading pause or market-wide trading halt. Currently, the Exchange's Trading Operations staff at the MIAX Help Desk issues a Post-Halt...(a). The Post-Halt Notification states the time at which trading in the option class or classes is...

Take a Tour of Our Facility | Energy Systems Integration Facility | NREL

Science.gov Websites

Take a Tour of Our Facility Take a Tour of Our Facility The Energy Systems Integration Facility Optical Characterization Laboratory System Performance Laboratory Power Systems Integration Laboratory Control Room Energy Storage Laboratory Outdoor Testing Areas Outdoor Testing Areas Energy Systems

Security in the CernVM File System and the Frontier Distributed Database Caching System

NASA Astrophysics Data System (ADS)

Dykstra, D.; Blomer, J.

2014-06-01

Both the CernVM File System (CVMFS) and the Frontier Distributed Database Caching System (Frontier) distribute centrally updated data worldwide for LHC experiments using http proxy caches. Neither system provides privacy or access control on reading the data, but both control access to updates of the data and can guarantee the authenticity and integrity of the data transferred to clients over the internet. CVMFS has since its early days required digital signatures and secure hashes on all distributed data, and recently Frontier has added X.509-based authenticity and integrity checking. In this paper we detail and compare the security models of CVMFS and Frontier.

Protection of the CERN Large Hadron Collider

NASA Astrophysics Data System (ADS)

Schmidt, R.; Assmann, R.; Carlier, E.; Dehning, B.; Denz, R.; Goddard, B.; Holzer, E. B.; Kain, V.; Puccio, B.; Todd, B.; Uythoven, J.; Wenninger, J.; Zerlauth, M.

2006-11-01

The Large Hadron Collider (LHC) at CERN will collide two counter-rotating proton beams, each with an energy of 7 TeV. The energy stored in the superconducting magnet system will exceed 10 GJ, and each beam has a stored energy of 362 MJ which could cause major damage to accelerator equipment in the case of uncontrolled beam loss. Safe operation of the LHC will therefore rely on a complex system for equipment protection. The systems for protection of the superconducting magnets in case of quench must be fully operational before powering the magnets. For safe injection of the 450 GeV beam into the LHC, beam absorbers must be in their correct positions and specific procedures must be applied. Requirements for safe operation throughout the cycle necessitate early detection of failures within the equipment, and active monitoring of the beam with fast and reliable beam instrumentation, mainly beam loss monitors (BLM). When operating with circulating beams, the time constant for beam loss after a failure extends from apms to a few minutes—failures must be detected sufficiently early and transmitted to the beam interlock system that triggers a beam dump. It is essential that the beams are properly extracted on to the dump blocks at the end of a fill and in case of emergency, since the beam dump blocks are the only elements of the LHC that can withstand the impact of the full beam.

Facilities | Argonne National Laboratory

Science.gov Websites

Skip to main content Argonne National Laboratory Toggle Navigation Toggle Search Research Facilities Advanced Powertrain Research Facility Center for Transportation Research Distributed Energy Research Center Engine Research Facility Heat Transfer Laboratory Materials Engineering Research Facility

EPA Facility Registry Service (FRS): Facility Interests Dataset - Intranet

EPA Pesticide Factsheets

This web feature service consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in the FRS individual feature layers. The layers comprise the FRS major program databases, including:Assessment Cleanup and Redevelopment Exchange System (ACRES) : brownfields sites ; Air Facility System (AFS) : stationary sources of air pollution ; Air Quality System (AQS) : ambient air pollution data from monitoring stations; Bureau of Indian Affairs (BIA) : schools data on Indian land; Base Realignment and Closure (BRAC) facilities; Clean Air Markets Division Business System (CAMDBS) : market-based air pollution control programs; Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) : hazardous waste sites; Integrated Compliance Information System (ICIS) : integrated enforcement and compliance information; National Compliance Database (NCDB) : Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Toxic Substances Control Act (TSCA); National Pollutant Discharge Elimination System (NPDES) module of ICIS : NPDES surface water permits; Radiation Information Database (RADINFO) : radiation and radioactivity facilities; RACT/BACT/LAER Clearinghouse (RBLC) : best available air pollution technology requirements; Resource Conservation and Recovery Act Information System (RCRAInfo) : tracks generators, transporters, treaters, storers, and disposers of haz

Association of U.S. Dialysis Facility Neighborhood Characteristics with Facility-Level Kidney Transplantation

PubMed Central

Plantinga, Laura; Pastan, Stephen; Kramer, Michael; McClellan, Ann; Krisher, Jenna; Patzer, Rachel E.

2014-01-01

Background Improving access to optimal healthcare may depend on attributes of neighborhoods where patients receive healthcare services. We investigated whether characteristics of dialysis facility neighborhoods—where most patients with end-stage renal disease are treated—were associated with facility-level kidney transplantation. Methods We examined the association between census tract (neighborhood)-level sociodemographic factors and facility-level kidney transplantation rate in 3,983 U.S. dialysis facilities with reported kidney transplantation rates. Number of kidney transplants and total person-years contributed at the facility level in 2007-2010 were obtained from the Dialysis Facility Report and linked to census tract data on sociodemographic characteristics from the American Community Survey 2006-2010 by dialysis facility location. We used multivariable Poisson models with generalized estimating equations to estimate associations between neighborhood characteristics and transplant incidence. Results U.S. dialysis facilities were located in neighborhoods with substantially greater proportions of black and poor residents, relative to the national average. Most facility neighborhood characteristics were associated with transplant, with incidence rate ratios (95% CI) for standardized increments (in percentage) of neighborhood exposures of: living in poverty, 0.88 (0.84-0.92), black race, 0.83 (0.78-0.89); high school graduates, 1.22 (1.17-1.26); and unemployed, 0.90 (0.85-0.95). Conclusion Dialysis facility neighborhood characteristics may be modestly associated with facility rates of kidney transplantation. The success of dialysis facility interventions to improve access to kidney transplantation may partially depend on reducing neighborhood-level barriers. PMID:25196018

Measurement And Calculation of High-Energy Neutron Spectra Behind Shielding at the CERF 120-GeV/C Hadron Beam Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nakao, N.; /SLAC; Taniguchi, S.

Neutron energy spectra were measured behind the lateral shield of the CERF (CERN-EU High Energy Reference Field) facility at CERN with a 120 GeV/c positive hadron beam (a mixture of mainly protons and pions) on a cylindrical copper target (7-cm diameter by 50-cm long). An NE213 organic liquid scintillator (12.7-cm diameter by 12.7-cm long) was located at various longitudinal positions behind shields of 80- and 160-cm thick concrete and 40-cm thick iron. The measurement locations cover an angular range with respect to the beam axis between 13 and 133{sup o}. Neutron energy spectra in the energy range between 32 MeVmore » and 380 MeV were obtained by unfolding the measured pulse height spectra with the detector response functions which have been verified in the neutron energy range up to 380 MeV in separate experiments. Since the source term and experimental geometry in this experiment are well characterized and simple and results are given in the form of energy spectra, these experimental results are very useful as benchmark data to check the accuracies of simulation codes and nuclear data. Monte Carlo simulations of the experimental set up were performed with the FLUKA, MARS and PHITS codes. Simulated spectra for the 80-cm thick concrete often agree within the experimental uncertainties. On the other hand, for the 160-cm thick concrete and iron shield differences are generally larger than the experimental uncertainties, yet within a factor of 2. Based on source term simulations, observed discrepancies among simulations of spectra outside the shield can be partially explained by differences in the high-energy hadron production in the copper target.« less

Facilities Performance Indicators Report 2011-12: Tracking Your Facilities Vital Signs

ERIC Educational Resources Information Center

APPA: Association of Higher Education Facilities Officers, 2013

2013-01-01

This paper provides an expanded Web-based "Facilities Performance Indicators (FPI) Report." The purpose of APPA's Facilities Performance Indicators is to provide a representative set of statistics about facilities in educational institutions. APPA's Information and Research Committee's goal for this year was to enhance the…

Footprints of Fascination: Digital Traces of Public Engagement with Particle Physics on CERN's Social Media Platforms.

PubMed

Kahle, Kate; Sharon, Aviv J; Baram-Tsabari, Ayelet

2016-01-01

Although the scientific community increasingly recognizes that its communication with the public may shape civic engagement with science, few studies have characterized how this communication occurs online. Social media plays a growing role in this engagement, yet it is not known if or how different platforms support different types of engagement. This study sets out to explore how users engage with science communication items on different platforms of social media, and what are the characteristics of the items that tend to attract large numbers of user interactions. Here, user interactions with almost identical items on five of CERN's social media platforms were quantitatively compared over an eight-week period, including likes, comments, shares, click-throughs, and time spent on CERN's site. The most popular items were qualitatively analyzed for content features. Findings indicate that as audience size of a social media platform grows, the total rate of engagement with content tends to grow as well. However, per user, engagement tends to decline with audience size. Across all platforms, similar topics tend to consistently receive high engagement. In particular, awe-inspiring imagery tends to frequently attract high engagement across platforms, independent of newsworthiness. To our knowledge, this study provides the first cross-platform characterization of public engagement with science on social media. Findings, although focused on particle physics, have a multidisciplinary nature; they may serve to benchmark social media analytics for assessing science communication activities in various domains. Evidence-based suggestions for practitioners are also offered.

Footprints of Fascination: Digital Traces of Public Engagement with Particle Physics on CERN's Social Media Platforms

PubMed Central

Baram-Tsabari, Ayelet

2016-01-01

Although the scientific community increasingly recognizes that its communication with the public may shape civic engagement with science, few studies have characterized how this communication occurs online. Social media plays a growing role in this engagement, yet it is not known if or how different platforms support different types of engagement. This study sets out to explore how users engage with science communication items on different platforms of social media, and what are the characteristics of the items that tend to attract large numbers of user interactions. Here, user interactions with almost identical items on five of CERN's social media platforms were quantitatively compared over an eight-week period, including likes, comments, shares, click-throughs, and time spent on CERN's site. The most popular items were qualitatively analyzed for content features. Findings indicate that as audience size of a social media platform grows, the total rate of engagement with content tends to grow as well. However, per user, engagement tends to decline with audience size. Across all platforms, similar topics tend to consistently receive high engagement. In particular, awe-inspiring imagery tends to frequently attract high engagement across platforms, independent of newsworthiness. To our knowledge, this study provides the first cross-platform characterization of public engagement with science on social media. Findings, although focused on particle physics, have a multidisciplinary nature; they may serve to benchmark social media analytics for assessing science communication activities in various domains. Evidence-based suggestions for practitioners are also offered. PMID:27232498

Centrifuge Facility Conceptual System Study. Volume 1: Facility overview and habitats

NASA Technical Reports Server (NTRS)

Synnestvedt, Robert (Editor)

1990-01-01

The results are presented for a NASA Phase 1 study conducted from mid 1987 through mid 1989 at Ames Research Center. The Centrifuge Facility is the major element of the biological research facility for the implementation of NASA's Life Science Research Program on Space Station Freedom using non-human specimens (such as small primates, rodents, plants, insects, cell tissues). Five systems are described which comprise the Facility: habitats, holding units, centrifuge, glovebox, and service unit. Volume 1 presents a facility overview and describes the habitats - modular units which house living specimens.

47 CFR 4.5 - Definitions of outage, special offices and facilities, and 911 special facilities.

Code of Federal Regulations, 2014 CFR

2014-10-01

... facilities, and 911 special facilities. 4.5 Section 4.5 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... Definitions of outage, special offices and facilities, and 911 special facilities. (a) Outage is defined as a... government facilities.” 911 special facilities are addressed separately in paragraph (e) of this section. (c...

Terbium Radionuclides for Theranostics Applications: A Focus On MEDICIS-PROMED

NASA Astrophysics Data System (ADS)

Cavaier, R. Formento; Haddad, F.; Sounalet, T.; Stora, T.; Zahi, I.

A new facility, named CERN-MEDICIS, is under construction at CERN to produce radionuclides for medical applications. In parallel, the MEDICIS-PROMED, a Marie Sklodowska-Curie innovative training network of the Horizon 2020 European Commission's program, is being coordinated by CERN to train young scientists on the production and use of innovative radionuclides and develop a network of experts within Europe. One program within MEDICIS-PROMED is to determine the feasibility of producing innovative radioisotopes for theranostics using a commercial middle-sized high-current cyclotron and the mass separation technology developed at CERN-MEDICIS. This will allow the production of high specific activity radioisotopes not achievable with the common post-processing by chemical separation. Radioisotopes of scandium, copper, arsenic and terbium have been identified. Preliminary studies of activation yield and irradiation parameters optimization for the production of Tb-149 will be described.

Energy Systems Integration Facility (ESIF) Facility Stewardship Plan: Revision 2.1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Torres, Juan; Anderson, Art

The U.S. Department of Energy (DOE), Office of Energy Efficiency and Renewable Energy (EERE), has established the Energy Systems Integration Facility (ESIF) on the campus of the National Renewable Energy Laboratory (NREL) and has designated it as a DOE user facility. This 182,500-ft2 research facility provides state-of-the-art laboratory and support infrastructure to optimize the design and performance of electrical, thermal, fuel, and information technologies and systems at scale. This Facility Stewardship Plan provides DOE and other decision makers with information about the existing and expected capabilities of the ESIF and the expected performance metrics to be applied to ESIF operations.more » This plan is a living document that will be updated and refined throughout the lifetime of the facility.« less

^{7}Be(n,α)^{4}He Reaction and the Cosmological Lithium Problem: Measurement of the Cross Section in a Wide Energy Range at n_TOF at CERN.

PubMed

Barbagallo, M; Musumarra, A; Cosentino, L; Maugeri, E; Heinitz, S; Mengoni, A; Dressler, R; Schumann, D; Käppeler, F; Colonna, N; Finocchiaro, P; Ayranov, M; Damone, L; Kivel, N; Aberle, O; Altstadt, S; Andrzejewski, J; Audouin, L; Bacak, M; Balibrea-Correa, J; Barros, S; Bécares, V; Bečvář, F; Beinrucker, C; Berthoumieux, E; Billowes, J; Bosnar, D; Brugger, M; Caamaño, M; Calviani, M; Calviño, F; Cano-Ott, D; Cardella, R; Casanovas, A; Castelluccio, D M; Cerutti, F; Chen, Y H; Chiaveri, E; Cortés, G; Cortés-Giraldo, M A; Cristallo, S; Diakaki, M; Domingo-Pardo, C; Dupont, E; Duran, I; Fernandez-Dominguez, B; Ferrari, A; Ferreira, P; Furman, W; Ganesan, S; García-Rios, A; Gawlik, A; Glodariu, T; Göbel, K; Gonçalves, I F; González-Romero, E; Griesmayer, E; Guerrero, C; Gunsing, F; Harada, H; Heftrich, T; Heyse, J; Jenkins, D G; Jericha, E; Katabuchi, T; Kavrigin, P; Kimura, A; Kokkoris, M; Krtička, M; Leal-Cidoncha, E; Lerendegui, J; Lederer, C; Leeb, H; Lo Meo, S; Lonsdale, S J; Losito, R; Macina, D; Marganiec, J; Martínez, T; Massimi, C; Mastinu, P; Mastromarco, M; Mazzone, A; Mendoza, E; Milazzo, P M; Mingrone, F; Mirea, M; Montesano, S; Nolte, R; Oprea, A; Pappalardo, A; Patronis, N; Pavlik, A; Perkowski, J; Piscopo, M; Plompen, A; Porras, I; Praena, J; Quesada, J; Rajeev, K; Rauscher, T; Reifarth, R; Riego-Perez, A; Rout, P; Rubbia, C; Ryan, J; Sabate-Gilarte, M; Saxena, A; Schillebeeckx, P; Schmidt, S; Sedyshev, P; Smith, A G; Stamatopoulos, A; Tagliente, G; Tain, J L; Tarifeño-Saldivia, A; Tassan-Got, L; Tsinganis, A; Valenta, S; Vannini, G; Variale, V; Vaz, P; Ventura, A; Vlachoudis, V; Vlastou, R; Vollaire, J; Wallner, A; Warren, S; Weigand, M; Weiß, C; Wolf, C; Woods, P J; Wright, T; Žugec, P

2016-10-07

The energy-dependent cross section of the ^{7}Be(n,α)^{4}He reaction, of interest for the so-called cosmological lithium problem in big bang nucleosynthesis, has been measured for the first time from 10 meV to 10 keV neutron energy. The challenges posed by the short half-life of ^{7}Be and by the low reaction cross section have been overcome at n_TOF thanks to an unprecedented combination of the extremely high luminosity and good resolution of the neutron beam in the new experimental area (EAR2) of the n_TOF facility at CERN, the availability of a sufficient amount of chemically pure ^{7}Be, and a specifically designed experimental setup. Coincidences between the two alpha particles have been recorded in two Si-^{7}Be-Si arrays placed directly in the neutron beam. The present results are consistent, at thermal neutron energy, with the only previous measurement performed in the 1960s at a nuclear reactor. The energy dependence reported here clearly indicates the inadequacy of the cross section estimates currently used in BBN calculations. Although new measurements at higher neutron energy may still be needed, the n_TOF results hint at a minor role of this reaction in BBN, leaving the long-standing cosmological lithium problem unsolved.

EPA Facility Registry Service (FRS): Facility Interests Dataset - Intranet Download

EPA Pesticide Factsheets

This downloadable data package consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in the FRS individual feature layers. The layers comprise the FRS major program databases, including:Assessment Cleanup and Redevelopment Exchange System (ACRES) : brownfields sites ; Air Facility System (AFS) : stationary sources of air pollution ; Air Quality System (AQS) : ambient air pollution data from monitoring stations; Bureau of Indian Affairs (BIA) : schools data on Indian land; Base Realignment and Closure (BRAC) facilities; Clean Air Markets Division Business System (CAMDBS) : market-based air pollution control programs; Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) : hazardous waste sites; Integrated Compliance Information System (ICIS) : integrated enforcement and compliance information; National Compliance Database (NCDB) : Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Toxic Substances Control Act (TSCA); National Pollutant Discharge Elimination System (NPDES) module of ICIS : NPDES surface water permits; Radiation Information Database (RADINFO) : radiation and radioactivity facilities; RACT/BACT/LAER Clearinghouse (RBLC) : best available air pollution technology requirements; Resource Conservation and Recovery Act Information System (RCRAInfo) : tracks generators, transporters, treaters, storers, and disposers

CernVM WebAPI - Controlling Virtual Machines from the Web

NASA Astrophysics Data System (ADS)

Charalampidis, I.; Berzano, D.; Blomer, J.; Buncic, P.; Ganis, G.; Meusel, R.; Segal, B.

2015-12-01

Lately, there is a trend in scientific projects to look for computing resources in the volunteering community. In addition, to reduce the development effort required to port the scientific software stack to all the known platforms, the use of Virtual Machines (VMs)u is becoming increasingly popular. Unfortunately their use further complicates the software installation and operation, restricting the volunteer audience to sufficiently expert people. CernVM WebAPI is a software solution addressing this specific case in a way that opens wide new application opportunities. It offers a very simple API for setting-up, controlling and interfacing with a VM instance in the users computer, while in the same time offloading the user from all the burden of downloading, installing and configuring the hypervisor. WebAPI comes with a lightweight javascript library that guides the user through the application installation process. Malicious usage is prohibited by offering a per-domain PKI validation mechanism. In this contribution we will overview this new technology, discuss its security features and examine some test cases where it is already in use.

One Year of FOS Measurements in CMS Experiment at CERN

NASA Astrophysics Data System (ADS)

Szillási, Zoltán; Buontempo, Salvatore; Béni, Noémi; Breglio, Giovanni; Cusano, Andrea; Laudati, Armando; Giordano, Michele; Saccomanno, Andrea; Druzhkin, Dmitry; Tsirou, Andromachi

Results are presented on the activity carried out by our research group, in collaboration with the SME Optosmart s.r.l. (an Italian spin-off company), on the application of Fiber Optic Sensor (FOS) techniques to monitor high-energy physics (HEP) detectors. Assuming that Fiber Bragg Grating sensors (FBGs) radiation hardness has been deeply studied for other field of application, we have applied the FBG technology to the HEP research domain. We present here the experimental evidences of the solid possibility to use such a class of sensors also in HEP detector very complex environmental side conditions. In particular we present more than one year data results of FBG measurements in the Compact Muon Solenoid (CMS) experiment set up at the CERN, where we have monitored temperatures (within CMS core) and strains in different locations by using FBG sensors during the detector operation with the Large Hadron Collider (LHC) collisions and high magnetic field. FOS data and FOS readout system stability and reliability is demonstrated, with continuous 24/24 h 7/7d data taking under severe and complex side conditions.

The Automation of the Transonic Experimental Facility (TEF) and the Aerodynamic Experimental Facility (AEF)

DTIC Science & Technology

2015-10-01

ARL-TR-7506 ● OCT 2015 US Army Research Laboratory The Automation of the Transonic Experimental Facility (TEF) and the...Laboratory The Automation of the Transonic Experimental Facility (TEF) and the Aerodynamic Experimental Facility (AEF) by Charith R Ranawake Weapons...To) 05/2015–08/2015 4. TITLE AND SUBTITLE The Automation of the Transonic Experimental Facility (TEF) and the Aerodynamic Experimental Facility

Evaluation of the Huawei UDS cloud storage system for CERN specific data

NASA Astrophysics Data System (ADS)

Zotes Resines, M.; Heikkila, S. S.; Duellmann, D.; Adde, G.; Toebbicke, R.; Hughes, J.; Wang, L.

2014-06-01

Cloud storage is an emerging architecture aiming to provide increased scalability and access performance, compared to more traditional solutions. CERN is evaluating this promise using Huawei UDS and OpenStack SWIFT storage deployments, focusing on the needs of high-energy physics. Both deployed setups implement S3, one of the protocols that are emerging as a standard in the cloud storage market. A set of client machines is used to generate I/O load patterns to evaluate the storage system performance. The presented read and write test results indicate scalability both in metadata and data perspectives. Futher the Huawei UDS cloud storage is shown to be able to recover from a major failure of losing 16 disks. Both cloud storages are finally demonstrated to function as back-end storage systems to a filesystem, which is used to deliver high energy physics software.

Engineering directorate technical facilities catalog

NASA Technical Reports Server (NTRS)

Maloy, Joseph E.

1993-01-01

The Engineering Directorate Technical Facilities Catalog is designed to provide an overview of the technical facilities available within the Engineering Directorate at the National Aeronautics and Space Administration (NASA), Lyndon B. Johnson Space Center (JSC) in Houston, Texas. The combined capabilities of these engineering facilities are essential elements of overall JSC capabilities required to manage and perform major NASA engineering programs. The facilities are grouped in the text by chapter according to the JSC division responsible for operation of the facility. This catalog updates the facility descriptions for the JSC Engineering Directorate Technical Facilities Catalog, JSC 19295 (August 1989), and supersedes the Engineering Directorate, Principle test and Development Facilities, JSC, 19962 (November 1984).

Analysis of CERN computing infrastructure and monitoring data

NASA Astrophysics Data System (ADS)

Nieke, C.; Lassnig, M.; Menichetti, L.; Motesnitsalis, E.; Duellmann, D.

2015-12-01

Optimizing a computing infrastructure on the scale of LHC requires a quantitative understanding of a complex network of many different resources and services. For this purpose the CERN IT department and the LHC experiments are collecting a large multitude of logs and performance probes, which are already successfully used for short-term analysis (e.g. operational dashboards) within each group. The IT analytics working group has been created with the goal to bring data sources from different services and on different abstraction levels together and to implement a suitable infrastructure for mid- to long-term statistical analysis. It further provides a forum for joint optimization across single service boundaries and the exchange of analysis methods and tools. To simplify access to the collected data, we implemented an automated repository for cleaned and aggregated data sources based on the Hadoop ecosystem. This contribution describes some of the challenges encountered, such as dealing with heterogeneous data formats, selecting an efficient storage format for map reduce and external access, and will describe the repository user interface. Using this infrastructure we were able to quantitatively analyze the relationship between CPU/wall fraction, latency/throughput constraints of network and disk and the effective job throughput. In this contribution we will first describe the design of the shared analysis infrastructure and then present a summary of first analysis results from the combined data sources.

Prospects for K+ →π+ ν ν ‾ observation at CERN in NA62

NASA Astrophysics Data System (ADS)

Khoriauli, G.; Aglieri Rinella, G.; Aliberti, R.; Ambrosino, F.; Angelucci, B.; Antonelli, A.; Anzivino, G.; Arcidiacono, R.; Azhinenko, I.; Balev, S.; Bendotti, J.; Biagioni, A.; Biino, C.; Bizzeti, A.; Blazek, T.; Blik, A.; Bloch-Devaux, B.; Bolotov, V.; Bonaiuto, V.; Bragadireanu, M.; Britton, D.; Britvich, G.; Bucci, F.; Butin, F.; Capitolo, E.; Capoccia, C.; Capussela, T.; Carassiti, V.; Cartiglia, N.; Cassese, A.; Catinaccio, A.; Cecchetti, A.; Ceccucci, A.; Cenci, P.; Cerny, V.; Cerri, C.; Checcucci, B.; Chikilev, O.; Ciaranfi, R.; Collazuol, G.; Conovaloff, A.; Cooke, P.; Cooper, P.; Corradi, G.; Cortina Gil, E.; Costantini, F.; Cotta Ramusino, A.; Coward, D.; D'Agostini, G.; Dainton, J.; Dalpiaz, P.; Danielsson, H.; Degrange, J.; De Simone, N.; Di Filippo, D.; Di Lella, L.; Dixon, N.; Doble, N.; Duk, V.; Elsha, V.; Engelfried, J.; Enik, T.; Falaleev, V.; Fantechi, R.; Fascianelli, V.; Federici, L.; Fiorini, M.; Fry, J.; Fucci, A.; Fulton, L.; Gallorini, S.; Gamberini, E.; Gatignon, L.; Georgiev, G.; Gianoli, A.; Giorgi, M.; Giudici, S.; Glonti, L.; Goncalves Martins, A.; Gonnella, F.; Goudzovski, E.; Guida, R.; Gushchin, E.; Hahn, F.; Hallgren, B.; Heath, H.; Herman, F.; Hutchcroft, D.; Iacopini, E.; Imbergamo, E.; Jamet, O.; Jarron, P.; Kampf, K.; Kaplon, J.; Karjavin, V.; Kekelidze, V.; Kholodenko, S.; Khoriauli, G.; Khudyakov, A.; Kiryushin, Yu.; Kleinknecht, K.; Kluge, A.; Koval, M.; Kozhuharov, V.; Krivda, M.; Kudenko, Y.; Kunze, J.; Lamanna, G.; Lazzeroni, C.; Lenci, R.; Lenti, M.; Leonardi, E.; Lichard, P.; Lietava, R.; Litov, L.; Lomidze, D.; Lonardo, A.; Lurkin, N.; Madigozhin, D.; Maire, G.; Makarov, A.; Mandeiro, C.; Mannelli, I.; Mannocchi, G.; Mapelli, A.; Marchetto, F.; Marchevski, R.; Martellotti, S.; Massarotti, P.; Massri, K.; Matak, P.; Maurice, E.; Menichetti, E.; Mila, G.; Minucci, E.; Mirra, M.; Misheva, M.; Molokanova, N.; Morant, J.; Morel, M.; Moulson, M.; Movchan, S.; Munday, D.; Napolitano, M.; Neri, I.; Newson, F.; Norton, A.; Noy, M.; Nuessle, G.; Obraztsov, V.; Ostankov, A.; Padolski, S.; Page, R.; Palladino, V.; Pardons, A.; Parkinson, C.; Pedreschi, E.; Pepe, M.; Perez Gomez, F.; Perrin-Terrin, M.; Peruzzo, L.; Petrov, P.; Petrucci, F.; Piandani, R.; Piccini, M.; Pietreanu, D.; Pinzino, J.; Pivanti, M.; Polenkevich, I.; Popov, I.; Potrebenikov, Yu.; Protopopescu, D.; Raffaelli, F.; Raggi, M.; Riedler, P.; Romano, A.; Rubin, P.; Ruggiero, G.; Russo, V.; Ryjov, V.; Salamon, A.; Salina, G.; Samsonov, V.; Santoni, C.; Santovetti, E.; Saracino, G.; Sargeni, F.; Schifano, S.; Semenov, V.; Sergi, A.; Serra, M.; Shkarovskiy, S.; Soldi, D.; Sotnikov, A.; Sougonyaev, V.; Sozzi, M.; Spadaro, T.; Spinella, F.; Staley, R.; Statera, M.; Sutcliffe, P.; Szilasi, N.; Tagnani, D.; Valdata-Nappi, M.; Valente, P.; Vasile, M.; Vassilieva, T.; Velghe, B.; Veltri, M.; Venditti, S.; Volpe, R.; Vormstein, M.; Wahl, H.; Wanke, R.; Wertelaers, P.; Winhart, A.; Winston, R.; Wrona, B.; Yushchenko, O.; Zamkovsky, M.; Zinchenko, A.; NA62 Collaboration

2016-01-01

The main physics goal of the NA62 experiment at CERN is to precisely measure the branching ratio of the Kaon rare decay K+ →π+ ν ν ‾. This decay is strongly suppressed in the Standard Model. On the other hand its branching ratio is calculated with high accuracy. NA62 is designed to measure the K+ →π+ ν ν ‾ decay rate with an uncertainty better than 10%. The measurement can serve as a probe to some new physics phenomena, which can alter the decay rate. The NA62 experiment has been successfully launched in October 2014. The theory framework as well as the NA62 detector and the preliminary results are reviewed in this article.

View of Facility 222 (on right) and Facility 221 through ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View of Facility 222 (on right) and Facility 221 through trees (parapet of latter above trees) from the parade ground. - U.S. Naval Base, Pearl Harbor, Gymnasium & Theater, Neville Way, Pearl City, Honolulu County, HI

R2 REGULATED FACILITIES

EPA Science Inventory

The Facility Registry System (FRS) is a centrally managed database that identifies facilities, sites or places subject to environmental regulations or of environmental interest. FRS creates high-quality, accurate, and authoritative facility identification records through rigorous...

FACILITY 316. EXTERIOR OBLIQUE OF FRONT AS SEEN FROM FACILITY ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

FACILITY 316. EXTERIOR OBLIQUE OF FRONT AS SEEN FROM FACILITY 362. VIEW FACING SOUTH. - U.S. Naval Base, Pearl Harbor, Naval Housing Area Hospital Point, Pharmacist's Quarters Type, 13-16 First Street, Pearl City, Honolulu County, HI

Gas-Grain Simulation Facility (GGSF). Volume 1: Stage 1 facility definition studies

NASA Technical Reports Server (NTRS)

Gat, Nahum

1993-01-01

The Gas-Grain Simulation Facility (GGSF) is a facility-type payload to be included in the Space Station Freedom (SSF). The GGSF is a multidisciplinary facility that will accommodate several classes of experiments, including exobiology, planetary science, atmospheric science, and astrophysics. The physical mechanisms envisioned to be investigated include crystal growth, aggregation, nucleation, coagulation, condensation, collisions, fractal growth, cycles of freezing and evaporation, scavenging, longevity of bacteria, and more. TRW performed a Phase A study that included analyses of the science and technical (S&T) requirements, the development of facility functional requirements, and a conceptual design of the facility. The work that was performed under Stage 1 of the Phase A study and the results to date are summarized. In this stage, facility definition studies were conducted in sufficient detail to establish the technical feasibility of the candidate strawman experiments. The studies identified technical difficulties, identified required facility subsystems, surveyed existing technology studies and established preliminary facility weight, volume, power consumption, data systems, interface definition, and crew time requirements. The results of this study served as the basis for Stage 2 of the Phase A study in which a conceptual design and a reference design were performed. The results also served as a basis for a related study for a Gas-Grain Simulation Experiment Module (GGSEM), which is an apparatus intended to perform a subset of the GGSF experiments on board a low-Earth-orbiting platform.

EPA Facility Registry Service (FRS): OIL

EPA Pesticide Factsheets

This dataset contains location and facility identification information from EPA's Facility Registry Service (FRS) for the subset of facilities that link to the Oil database. The Oil database contains information on Spill Prevention, Control, and Countermeasure (SPCC) and Facility Response Plan (FRP) subject facilities to prevent and respond to oil spills. FRP facilities are referred to as substantial harm facilities due to the quantities of oil stored and facility characteristics. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to Oil facilities once the Oil data has been integrated into the FRS database. Additional information on FRS is available at the EPA website https://www.epa.gov/enviro/facility-registry-service-frs.

Brightness and uniformity measurements of plastic scintillator tiles at the CERN H2 test beam

NASA Astrophysics Data System (ADS)

Chatrchyan, S.; Sirunyan, A. M.; Tumasyan, A.; Litomin, A.; Mossolov, V.; Shumeiko, N.; Van De Klundert, M.; Van Haevermaet, H.; Van Mechelen, P.; Van Spilbeeck, A.; Alves, G. A.; Aldá Júnior, W. L.; Hensel, C.; Carvalho, W.; Chinellato, J.; De Oliveira Martins, C.; Matos Figueiredo, D.; Mora Herrera, C.; Nogima, H.; Prado Da Silva, W. L.; Tonelli Manganote, E. J.; Vilela Pereira, A.; Finger, M.; Finger, M., Jr.; Kveton, A.; Tomsa, J.; Adamov, G.; Tsamalaidze, Z.; Behrens, U.; Borras, K.; Campbell, A.; Costanza, F.; Gunnellini, P.; Lobanov, A.; Melzer-Pellmann, I.-A.; Muhl, C.; Roland, B.; Sahin, M.; Saxena, P.; Hegde, V.; Kothekar, K.; Pandey, S.; Sharma, S.; Beri, S. B.; Bhawandeep, B.; Chawla, R.; Kalsi, A.; Kaur, A.; Kaur, M.; Walia, G.; Bhattacharya, S.; Ghosh, S.; Nandan, S.; Purohit, A.; Sharan, M.; Banerjee, S.; Bhattacharya, S.; Chatterjee, S.; Das, P.; Guchait, M.; Jain, S.; Kumar, S.; Maity, M.; Majumder, G.; Mazumdar, K.; Patil, M.; Sarkar, T.; Juodagalvis, A.; Afanasiev, S.; Bunin, P.; Ershov, Y.; Golutvin, I.; Malakhov, A.; Moisenz, P.; Smirnov, V.; Zarubin, A.; Chadeeva, M.; Chistov, R.; Danilov, M.; Popova, E.; Rusinov, V.; Andreev, Yu.; Dermenev, A.; Karneyeu, A.; Krasnikov, N.; Tlisov, D.; Toropin, A.; Epshteyn, V.; Gavrilov, V.; Lychkovskaya, N.; Popov, V.; Pozdnyakov, I.; Safronov, G.; Toms, M.; Zhokin, A.; Baskakov, A.; Belyaev, A.; Boos, E.; Dubinin, M.; Dudko, L.; Ershov, A.; Gribushin, A.; Kaminskiy, A.; Klyukhin, V.; Kodolova, O.; Lokhtin, I.; Miagkov, I.; Obraztsov, S.; Petrushanko, S.; Savrin, V.; Snigirev, A.; Andreev, V.; Azarkin, M.; Dremin, I.; Kirakosyan, M.; Leonidov, A.; Terkulov, A.; Bitioukov, S.; Elumakhov, D.; Kalinin, A.; Krychkine, V.; Mandrik, P.; Petrov, V.; Ryutin, R.; Sobol, A.; Troshin, S.; Volkov, A.; Sekmen, S.; Medvedeva, T.; Rumerio, P.; Adiguzel, A.; Bakirci, N.; Boran, F.; Cerci, S.; Damarseckin, S.; Demiroglu, Z. S.; Dölek, F.; Dozen, C.; Dumanoglu, I.; Eskut, E.; Girgis, S.; Gokbulut, G.; Guler, Y.; Hos, I.; Kangal, E. E.; Kara, O.; Kayis Topaksu, A.; Işik, C.; Kiminsu, U.; Oglakci, M.; Onengut, G.; Ozdemir, K.; Ozturk, S.; Polatoz, A.; Sunar Cerci, D.; Tali, B.; Tok, U. G.; Topakli, H.; Turkcapar, S.; Zorbakir, I. S.; Zorbilmez, C.; Bilin, B.; Isildak, B.; Karapinar, G.; Murat Guler, A.; Ocalan, K.; Yalvac, M.; Zeyrek, M.; Atakisi, I. O.; Gülmez, E.; Kaya, M.; Kaya, O.; Koseyan, O. K.; Ozcelik, O.; Ozkorucuklu, S.; Tekten, S.; Yetkin, E. A.; Yetkin, T.; Cankocak, K.; Sen, S.; Boyarintsev, A.; Grynyov, B.; Levchuk, L.; Popov, V.; Sorokin, P.; Flacher, H.; Borzou, A.; Call, K.; Dittmann, J.; Hatakeyama, K.; Liu, H.; Pastika, N.; Buccilli, A.; Cooper, S. I.; Henderson, C.; West, C.; Arcaro, D.; Gastler, D.; Hazen, E.; Rohlf, J.; Sulak, L.; Wu, S.; Zou, D.; Hakala, J.; Heintz, U.; Kwok, K. H. M.; Laird, E.; Landsberg, G.; Mao, Z.; Yu, D. R.; Gary, J. W.; Ghiasi Shirazi, S. M.; Lacroix, F.; Long, O. R.; Wei, H.; Bhandari, R.; Heller, R.; Stuart, D.; Yoo, J. H.; Chen, Y.; Duarte, J.; Lawhorn, J. M.; Nguyen, T.; Spiropulu, M.; Winn, D.; Abdullin, S.; Apresyan, A.; Apyan, A.; Banerjee, S.; Chlebana, F.; Freeman, J.; Green, D.; Hare, D.; Hirschauer, J.; Joshi, U.; Lincoln, D.; Los, S.; Pedro, K.; Spalding, W. J.; Strobbe, N.; Tkaczyk, S.; Whitbeck, A.; Linn, S.; Markowitz, P.; Martinez, G.; Bertoldi, M.; Hagopian, S.; Hagopian, V.; Kolberg, T.; Baarmand, M. M.; Noonan, D.; Roy, T.; Yumiceva, F.; Bilki, B.; Clarida, W.; Debbins, P.; Dilsiz, K.; Durgut, S.; Gandrajula, R. P.; Haytmyradov, M.; Khristenko, V.; Merlo, J.-P.; Mermerkaya, H.; Mestvirishvili, A.; Miller, M.; Moeller, A.; Nachtman, J.; Ogul, H.; Onel, Y.; Ozok, F.; Penzo, A.; Schmidt, I.; Snyder, C.; Southwick, D.; Tiras, E.; Yi, K.; Al-bataineh, A.; Bowen, J.; Castle, J.; McBrayer, W.; Murray, M.; Wang, Q.; Kaadze, K.; Maravin, Y.; Mohammadi, A.; Saini, L. K.; Baden, A.; Belloni, A.; Calderon, J. D.; Eno, S. C.; Feng, Y. B.; Ferraioli, C.; Grassi, T.; Hadley, N. J.; Jeng, G.-Y.; Kellogg, R. G.; Kunkle, J.; Mignerey, A.; Ricci-Tam, F.; Shin, Y. H.; Skuja, A.; Yang, Z. S.; Yao, Y.; Brandt, S.; D'Alfonso, M.; Hu, M.; Klute, M.; Niu, X.; Chatterjee, R. M.; Evans, A.; Frahm, E.; Kubota, Y.; Lesko, Z.; Mans, J.; Ruckstuhl, N.; Heering, A.; Karmgard, D. J.; Musienko, Y.; Ruchti, R.; Wayne, M.; Benaglia, A. D.; Mei, K.; Tully, C.; Bodek, A.; de Barbaro, P.; Galanti, M.; Garcia-Bellido, A.; Khukhunaishvili, A.; Lo, K. H.; Vishnevskiy, D.; Zielinski, M.; Agapitos, A.; Amouzegar, M.; Chou, J. P.; Hughes, E.; Saka, H.; Sheffield, D.; Akchurin, N.; Damgov, J.; De Guio, F.; Dudero, P. R.; Faulkner, J.; Gurpinar, E.; Kunori, S.; Lamichhane, K.; Lee, S. W.; Libeiro, T.; Mengke, T.; Muthumuni, S.; Undleeb, S.; Volobouev, I.; Wang, Z.; Goadhouse, S.; Hirosky, R.; Wang, Y.

2018-01-01

We study the light output, light collection efficiency and signal timing of a variety of organic scintillators that are being considered for the upgrade of the hadronic calorimeter of the CMS detector. The experimental data are collected at the H2 test-beam area at CERN, using a 150 GeV muon beam. In particular, we investigate the usage of over-doped and green-emitting plastic scintillators, two solutions that have not been extensively considered. We present a study of the energy distribution in plastic-scintillator tiles, the hit efficiency as a function of the hit position, and a study of the signal timing for blue and green scintillators.

10 CFR 70.64 - Requirements for new facilities or new processes at existing facilities.

Code of Federal Regulations, 2011 CFR

2011-01-01

... behavior of items relied on for safety. (b) Facility and system design and facility layout must be based on... existing facilities. (a) Baseline design criteria. Each prospective applicant or licensee shall address the following baseline design criteria in the design of new facilities. Each existing licensee shall address the...

10 CFR 70.64 - Requirements for new facilities or new processes at existing facilities.

Code of Federal Regulations, 2013 CFR

2013-01-01

... behavior of items relied on for safety. (b) Facility and system design and facility layout must be based on... existing facilities. (a) Baseline design criteria. Each prospective applicant or licensee shall address the following baseline design criteria in the design of new facilities. Each existing licensee shall address the...

10 CFR 70.64 - Requirements for new facilities or new processes at existing facilities.

Code of Federal Regulations, 2012 CFR

2012-01-01

... behavior of items relied on for safety. (b) Facility and system design and facility layout must be based on... existing facilities. (a) Baseline design criteria. Each prospective applicant or licensee shall address the following baseline design criteria in the design of new facilities. Each existing licensee shall address the...

10 CFR 70.64 - Requirements for new facilities or new processes at existing facilities.

Code of Federal Regulations, 2014 CFR

2014-01-01

... behavior of items relied on for safety. (b) Facility and system design and facility layout must be based on... existing facilities. (a) Baseline design criteria. Each prospective applicant or licensee shall address the following baseline design criteria in the design of new facilities. Each existing licensee shall address the...

FACILITY 317. EXTERIOR OF FRONT SIDE, WITH FACILITY 316 BEYOND ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

FACILITY 317. EXTERIOR OF FRONT SIDE, WITH FACILITY 316 BEYOND ON THE LEFT. VIEW FACING NORTH. - U.S. Naval Base, Pearl Harbor, Naval Housing Area Hospital Point, Pharmacist's Quarters Type, 13-16 First Street, Pearl City, Honolulu County, HI

Facility safety study

NASA Technical Reports Server (NTRS)

1979-01-01

The safety of NASA's in house microelectronics facility is addressed. Industrial health standards, facility emission control requirements, operation and safety checklists, and the disposal of epitaxial vent gas are considered.

The National Ignition Facility: Transition to a User Facility

NASA Astrophysics Data System (ADS)

Moses, E. I.; Atherton, J.; Lagin, L.; Larson, D.; Keane, C.; MacGowan, B.; Patterson, R.; Spaeth, M.; Van Wonterghem, B.; Wegner, P.; Kauffman, R.

2016-03-01

The National Ignition Facility (NIF) at Lawrence Livermore National Laboratory (LLNL) has been operational since March 2009 and has been transitioning to a user facility supporting ignition science, high energy density science (HEDS), national security applications, and fundamental science. The facility has achieved its design goal of 1.8 MJ and 500 TW of 3ω light on target, and has performed target experiments with 1.9 MJ at peak powers of 410 TW. The facility is on track to perform over 200 target shots this year in support of all of its user communities. The facility has nearly 60 diagnostic systems operational and has shown flexibility in laser pulse shape and performance to meet the requirements of its multiple users. Progress continues on its goal of demonstrating thermonuclear burn in the laboratory. It has performed over 40 indirect-drive experiments with cryogenic-layered capsules. New platforms are being developed for HEDS and fundamental science. Equation-of-state and material strength experiments have been done on a number of materials with pressures of over 50 MBars obtained in diamond, conditions never previously encountered in the laboratory and similar to those found in planetary interiors. Experiments are also in progress investigating radiation transport, hydrodynamic instabilities, and direct drive implosions. NIF continues to develop as an experimental facility. Advanced Radiographic Capability (ARC) is now being installed on NIF for producing high-energy radiographs of the imploded cores of ignition targets and for short pulse laser-plasma interaction experiments. One NIF beam is planned for conversion to two picosecond beams in 2014. Other new diagnostics such as x-ray Thomson scattering, low energy neutron spectrometer, and multi-layer reflecting x-ray optics are also planned. Incremental improvements in laser performance such as improved optics damage performance, beam balance, and back reflection control are being pursued.

VIEW TO NORTHWEST, SHOWING FACILITY NO. 525 AND HOSPITAL (FACILITY ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

VIEW TO NORTHWEST, SHOWING FACILITY NO. 525 AND HOSPITAL (FACILITY No. 515) BEYOND. See CA-2398-CP-8 for detail of the stairway in the distance - Hamilton Field, Amphitheater, North Oakland Drive near East Hospital Drive, Novato, Marin County, CA

Surviving the storms: Emergency preparedness in Texas nursing facilities and assisted living facilities.

PubMed

Castro, Carmen; Persson, Diane; Bergstrom, Nancy; Cron, Stanley

2008-08-01

This study assesses the preparedness of long-term care facilities in Texas responding to Hurricanes Katrina and Rita. A 41-item questionnaire was mailed to facilities; the response rate was 42%. Among responding facilities, 4513 residents were evacuated, and 6% of respondents reported resident death. Financial losses were reported by 8% of nursing facilities and 45% of assisted living facilities due to transportation and staff overtime. Respondents indicated the need for improved disaster preparednesstraining, better coordination, and transportation. Changes in policy and practice will lead to better trained staff who will provide the care residents need for improved health outcomes during future public health disasters.

Comprehensive facilities plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-09-01

The Ernest Orlando Lawrence Berkeley National Laboratory`s Comprehensive Facilities Plan (CFP) document provides analysis and policy guidance for the effective use and orderly future development of land and capital assets at the Berkeley Lab site. The CFP directly supports Berkeley Lab`s role as a multiprogram national laboratory operated by the University of California (UC) for the Department of Energy (DOE). The CFP is revised annually on Berkeley Lab`s Facilities Planning Website. Major revisions are consistent with DOE policy and review guidance. Facilities planing is motivated by the need to develop facilities for DOE programmatic needs; to maintain, replace and rehabilitatemore » existing obsolete facilities; to identify sites for anticipated programmatic growth; and to establish a planning framework in recognition of site amenities and the surrounding community. The CFP presents a concise expression of the policy for the future physical development of the Laboratory, based upon anticipated operational needs of research programs and the environmental setting. It is a product of the ongoing planning processes and is a dynamic information source.« less

The National Scientific Balloon Facility. [balloon launching capabilities of ground facility

NASA Technical Reports Server (NTRS)

Kubara, R. S.

1974-01-01

The establishment and operation of the National Scientific Balloon Facility are discussed. The balloon launching capabilities are described. The ground support systems, communication facilities, and meteorological services are analyzed.

Substance Abuse Treatment in Adult and Juvenile Correctional Facilities: Findings from the Uniform Facility Data Set 1997 Survey of Correctional Facilities.

ERIC Educational Resources Information Center

Marsden, Mary Ellen, Ed.; Straw, Richard S., Ed.

This report presents methodology and findings from the Uniform Facility Data Set (UFDS) 1997 Survey of Correctional Facilities, which surveyed about 7,600 adult and juvenile correctional facilities to identify those that provide on-site substance abuse treatment to their inmates or residents. The survey assesses substance abuse treatment provided…

Towards a Future Linear Collider and The Linear Collider Studies at CERN

ScienceCinema

Heuer, Rolf-Dieter

2018-06-15

During the week 18-22 October, more than 400 physicists will meet at CERN and in the CICG (International Conference Centre Geneva) to review the global progress towards a future linear collider. The 2010 International Workshop on Linear Colliders will study the physics, detectors and accelerator complex of a linear collider covering both the CLIC and ILC options. Among the topics presented and discussed will be the progress towards the CLIC Conceptual Design Report in 2011, the ILC Technical Design Report in 2012, physics and detector studies linked to these reports, and an increasing numbers of common working group activities. The seminar will give an overview of these topics and also CERN’s linear collider studies, focusing on current activities and initial plans for the period 2011-16. n.b: The Council Chamber is also reserved for this colloquium with a live transmission from the Main Auditorium.

Towards a Future Linear Collider and The Linear Collider Studies at CERN

ScienceCinema

Stapnes, Steinar

2017-12-18

During the week 18-22 October, more than 400 physicists will meet at CERN and in the CICG (International Conference Centre Geneva) to review the global progress towards a future linear collider. The 2010 International Workshop on Linear Colliders will study the physics, detectors and accelerator complex of a linear collider covering both the CLIC and ILC options. Among the topics presented and discussed will be the progress towards the CLIC Conceptual Design Report in 2011, the ILC Technical Design Report in 2012, physics and detector studies linked to these reports, and an increasing numbers of common working group activities. The seminar will give an overview of these topics and also CERN’s linear collider studies, focusing on current activities and initial plans for the period 2011-16. n.b: The Council Chamber is also reserved for this colloquium with a live transmission from the Main Auditorium.

Comprehensive interpretation of thermal dileptons measured at the CERN super proton synchrotron.

PubMed

van Hees, Hendrik; Rapp, Ralf

2006-09-08

Employing thermal dilepton rates based on a medium-modified electromagnetic correlation function we show that recent dimuon spectra of the NA60 Collaboration in central In-In collisions at the CERN-SPS can be understood in terms of radiation from a hot and dense hadronic medium. Earlier calculated in-medium rho-meson spectral functions provide an accurate description of the data up to dimuon invariant masses of about M approximately or equal to 0.9 GeV, with good sensitivity to the predicted rho-meson line shape, identifying baryon-induced modifications as the prevalent ones. A reliable evaluation of the contribution enables the study of further medium effects: at masses M>0.9 GeV, 4-pion type annihilation accounts for the experimentally observed excess (possibly augmented by effects of "chiral mixing"), while predictions for thermal emission from in-medium omega and phi mesons may be tested in the future.

75 FR 28841 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-24

... Change To Amend FINRA Rule 6121 (Trading Halts Due to Extraordinary Market Volatility) May 19, 2010... Halts Due to Extraordinary Market Volatility) to permit FINRA to halt trading by FINRA members otherwise... October 2008, FINRA adopted FINRA Rule 6121 (Trading Halts Due to Extraordinary Market Volatility) to...

Facilities Engineering in NASA

NASA Technical Reports Server (NTRS)

Pagluiso, M. A.

1970-01-01

An overview of NASA facilities is given outlining some of the more interesting and unique aspects of engineering and facilities associated with the space program. Outlined are some of the policies under which the Office of Facilities conducts its business. Included are environmental quality control measures.

Florida Educational Facilities, 1996.

ERIC Educational Resources Information Center

Florida State Dept. of Education, Tallahassee. Office of Educational Facilities.

This document contains information, photographs, and floor plans of many of Florida's new elementary through high school facilities occupied in 1996. Each entry lists the facility's type, building size, student capacity, and general structural information. Also provided is information on the facility's total construction cost; the architects and…

Florida Educational Facilities, 1997.

ERIC Educational Resources Information Center

Florida State Dept. of Education, Tallahassee. Office of Educational Facilities.

This document contains information, photographs, and floor plans of many of Florida's new elementary through high school facilities occupied in 1997. Each entry lists the facility's type, building size, student capacity, and general structural information. Also provided is information on the facility's total construction cost; the architects and…

Florida Educational Facilities, 1998.

ERIC Educational Resources Information Center

Florida State Dept. of Education, Tallahassee. Office of Educational Facilities.

This document contains information, photographs, and floor plans of many of Florida's new elementary through high school facilities occupied in 1998. Each entry lists the facility's type, building size, student capacity, and general structural information. Also provided is information on the facility's total construction cost; the architects and…

Holding Area LINQ Trial (HALT).

PubMed

Lee, John J; Weitz, Daniel; Anand, Rishi

Recent studies have shown that insertable cardiac monitors (ICMs) can be implanted out of the traditional hospital setting and efforts are being made to explore the feasibility of implanting these devices in a specific standardized location other than the operating room or a cardiac catherization/electrophysiology lab. This was a prospective, non-randomized, single center post-market clinical trial designed to occur in the holding area of a hospital operating room or cardiac catheterization/electrophysiology laboratory. The Medtronic Reveal LINQ ICM was implanted and patients were followed for 90 days post implant. This study was designed to observe any procedure related adverse events stemming from the holding area implantation. Twenty patients were implanted at our hospital in a holding room not traditionally associated with the electrophysiology/cardiac/operatory labs. One patient was lost to the 90-day follow up. In one case, ICM implantation led to diagnosis requiring removal of ICM before the 90 day follow up and insertion of a biventricular implantable cardioverter defibrillator (ICD). In the remaining 18 patients, there were no serious complications such as minor skin infections, systemic infections or procedure-related adverse events requiring device explant. When following a standardized protocol with attention to sterile technique, it is feasible to implant ICMs in a holding area with no procedure related adverse events (AE). Copyright © 2017 Indian Heart Rhythm Society. Production and hosting by Elsevier B.V. All rights reserved.

How to Halt Student Dishonesty.

ERIC Educational Resources Information Center

Singhal, Avinash C.; Johnson, Patti

1983-01-01

Outlines methods to prevent cheating in colleges by: (1) defining the problem; (2) describing physical arrangements of testing situations; and (3) stressing the importance of detection and retributions for academic dishonesty. The individual faculty member should control cheating. A "cheating" table provides suggestions for detecting and…

National Facilities study

NASA Technical Reports Server (NTRS)

1994-01-01

This study provides a set of recommendations for improving the effectiveness of our nation's aeronautics and space facilities. The study plan considers current and future government and commercial needs as well as DOD and NASA mission requirements through the year 2023. It addresses shortfalls in existing capabilities, new facility requirements, upgrades, consolidations, and phase-out of existing facilities. If the recommendations are implemented, they will provide world-class capability where it is vital to our country's needs and make us more efficient in meeting future needs.

Facility effluent monitoring plan for the plutonium uranium extraction facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wiegand, D.L.

A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438-01. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements. This facility effluent monitoring plan shall ensure long-range integrity of themore » effluent monitoring systems by requiring an update whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document must be reviewed annually even if there are no operational changes, and it must be updated at a minimum of every three years.« less

9 CFR 351.10 - Facilities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Facilities. 351.10 Section 351.10... CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Facilities and Operations § 351.10 Facilities. (a) Facilities for the preparation, identification, and storage of the technical animal fat to be...

Facilities Utilization Program Implementation Handbook

NASA Technical Reports Server (NTRS)

1987-01-01

This Facilities Utilization Program Implementation Handbook (FUPIH) prescribes procedures for the review and the reporting on the utilization of NASA facilities. The Directors of NASA Field Installations should designate an Installation Official responsible for coordinating the assignment of buildings space and implementing the facilities utilization reviews and annual report preparation. The individual designated shall be known as the 'Facilities Utilization Officer (FUO).' Functional responsibilities of the FUO are detailed in NASA Management Instruction (NMI) 7234.1. It is recognized that titles used in the implementation of the Facilities Utilization Program may vary between field installations. The Facilities Utilization Program (FUP) is designed to provide a uniform and orderly process for meeting or addressing the following objectives: the establishment of sound facilities requirements to meet NASA's programmatic and institutional needs; the optimum allocation of available facilities and related resources to meet these requirements; and the early identification and request for required additional facilities resources. The detailed review and reporting system enacted by NMI 7234.1 should encourage more comprehensive utilization planning for all NASA facilities and ensure, to the maximum extent practicable, that all such facilities are put to their highest and best use consistent with NASA programmatic and institutional priorities. A principal purpose of the FUP is the early identification of NASA facilities which may be or may become underutilized or excess to NASA needs and to provide a timely reference point from which corrective actions (i.e., consolidation, elimination of duplication, improved utilization of disposal) may be taken. Because the supply of this handbook is limited, distribution should be controlled at the field installation level.

The National Ignition Facility (NIF) as a User Facility

NASA Astrophysics Data System (ADS)

Keane, Christopher; NIF Team

2013-10-01

The National Ignition Facility (NIF) has made significant progress towards operation as a user facility. Through June 2013, NIF conducted over 1200 experiments in support of ICF, HED science, and development of facility capabilities. The NIF laser has met or achieved all specifications and a wide variety of diagnostic and target fabrication capabilities are in place. A NIF User Group and associated Executive Board have been formed. Two User Group meetings have been conducted since formation of the User Group. NIF experiments in fundamental science have provided important new results. NIF ramp compression experiments have been conducted using diamond and iron, with EOS results obtained at pressures up to approximately 50 Mbar and 8 Mbar, respectively. Initial experiments in supernova hydrodynamics, the fundamental physics of the Rayleigh-Taylor instability, and equation of state in the Gbar pressure regime have also been conducted. This presentation will discuss the fundamental science program at NIF, including the proposal solicitation and scientific review processes and other aspects of user facility operation. This work was performed under the auspices of the Lawrence Livermore National Security, LLC, (LLNS) under Contract No. DE-AC52-07NA27344.

Challenges for proteomics core facilities.

PubMed

Lilley, Kathryn S; Deery, Michael J; Gatto, Laurent

2011-03-01

Many analytical techniques have been executed by core facilities established within academic, pharmaceutical and other industrial institutions. The centralization of such facilities ensures a level of expertise and hardware which often cannot be supported by individual laboratories. The establishment of a core facility thus makes the technology available for multiple researchers in the same institution. Often, the services within the core facility are also opened out to researchers from other institutions, frequently with a fee being levied for the service provided. In the 1990s, with the onset of the age of genomics, there was an abundance of DNA analysis facilities, many of which have since disappeared from institutions and are now available through commercial sources. Ten years on, as proteomics was beginning to be utilized by many researchers, this technology found itself an ideal candidate for being placed within a core facility. We discuss what in our view are the daily challenges of proteomics core facilities. We also examine the potential unmet needs of the proteomics core facility that may also be applicable to proteomics laboratories which do not function as core facilities. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

SD46 Facilities and Capabilities

NASA Technical Reports Server (NTRS)

Ramachandran, N.; Curreri, Peter A. (Technical Monitor)

2002-01-01

The displays for the Materials Conference presents some of the facilities and capabilities in SD46 that can be useful to a prospective researcher from University, Academia or other government labs. Several of these already have associated personnel as principal and co-investigators on NASA peer reviewed science investigations. 1. SCN purification facility 2. ESL facility 3. Static and Dynamic magnetic field facility 4. Microanalysis facility 5. MSG Investigation - PFMI 6. Thermo physical Properties Measurement Capabilities.

Considerations on Facilities Planning

ERIC Educational Resources Information Center

Baule, Steven

2007-01-01

Most facilities renovation projects occur because someone at the executive or board level has lobbied successfully for them. Often in public schools, the voters have agreed to the project as well via a building referendum. Therefore, facilities projects are highly visible to the community. Unlike many other issues in schools, facilities projects…

National facilities study. Volume 5: Space research and development facilities task group

NASA Technical Reports Server (NTRS)

1994-01-01

With the beginnings of the U.S. space program, there was a pressing need to develop facilities that could support the technology research and development, testing, and operations of evolving space systems. Redundancy in facilities that was once and advantage in providing flexibility and schedule accommodation is instead fast becoming a burden on scarce resources. As a result, there is a clear perception in many sectors that the U.S. has many space R&D facilities that are under-utilized and which are no longer cost-effective to maintain. At the same time, it is clear that the U.S. continues to possess many space R&D facilities which are the best -- or among the best -- in the world. In order to remain world class in key areas, careful assessment of current capabilities and planning for new facilities is needed. The National Facility Study (NFS) was initiated in 1992 to develop a comprehensive and integrated long-term plan for future aerospace facilities that meets current and projected government and commercial needs. In order to assess the nation's capability to support space research and development (R&D), a Space R&D Task Group was formed. The Task Group was co-chaired by NASA and DOD. The Task Group formed four major, technologically- and functionally- oriented working groups: Human and Machine Operations; Information and Communications; Propulsion and Power; and Materials, Structures, and Flight Dynamics. In addition to these groups, three supporting working groups were formed: Systems Engineering and Requirements; Strategy and Policy; and Costing Analysis. The Space R&D Task Group examined several hundred facilities against the template of a baseline mission and requirements model (developed in common with the Space Operations Task Group) and a set of excursions from the baseline. The model and excursions are described in Volume 3 of the NFS final report. In addition, as a part of the effort, the group examined key strategic issues associated with space R

Brief Survey of TSC Computing Facilities

DOT National Transportation Integrated Search

1972-05-01

The Transportation Systems Center (TSC) has four, essentially separate, in-house computing facilities. We shall call them Honeywell Facility, the Hybrid Facility, the Multimode Simulation Facility, and the Central Facility. In addition to these four,...

Two-particle correlations in azimuthal angle and pseudorapidity in inelastic p + p interactions at the CERN Super Proton Synchrotron

DOE PAGES

Aduszkiewicz, A.; Ali, Y.; Andronov, E.; ...

2017-01-30

Results on two-particle ΔηΔΦ correlations in inelastic p + p interactions at 20, 31, 40, 80, and 158 GeV/c are presented. The measurements were performed using the large acceptance NA61/SHINE hadron spectrometer at the CERN Super Proton Synchrotron. The data show structures which can be attributed mainly to effects of resonance decays, momentum conservation, and quantum statistics. Furthermore, the results are compared with the Epos and UrQMD models.

Wind Energy Facilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Laurie, Carol

2017-02-01

This book takes readers inside the places where daily discoveries shape the next generation of wind power systems. Energy Department laboratory facilities span the United States and offer wind research capabilities to meet industry needs. The facilities described in this book make it possible for industry players to increase reliability, improve efficiency, and reduce the cost of wind energy -- one discovery at a time. Whether you require blade testing or resource characterization, grid integration or high-performance computing, Department of Energy laboratory facilities offer a variety of capabilities to meet your wind research needs.

Wind Energy Facilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Office of Energy Efficiency and Renewable Energy

This book takes readers inside the places where daily discoveries shape the next generation of wind power systems. Energy Department laboratory facilities span the United States and offer wind research capabilities to meet industry needs. The facilities described in this book make it possible for industry players to increase reliability, improve efficiency, and reduce the cost of wind energy -- one discovery at a time. Whether you require blade testing or resource characterization, grid integration or high-performance computing, Department of Energy laboratory facilities offer a variety of capabilities to meet your wind research needs.

INCINERATION RESEARCH FACILITY

EPA Science Inventory

The Cincinnati-based Risk Reduction Engineering Laboratory, ORD, U.S. EPA operates the Incineration Research Facility *IRF) in Jefferson, Arkansas. This facility's pilot-scale experimental incineration systems include a Rotary Kiln System and a Liquid Injection System. Each syste...

Alleviation of Facility/Engine Interactions in an Open-Jet Scramjet Test Facility

NASA Technical Reports Server (NTRS)

Albertson, Cindy W.; Emami, Saied

2001-01-01

Results of a series of shakedown tests to eliminate facility/engine interactions in an open-jet scramjet test facility are presented. The tests were conducted with the NASA DFX (Dual-Fuel eXperimental scramjet) engine in the NASA Langley Combustion Heated Scramjet Test Facility (CHSTF) in support of the Hyper-X program, The majority of the tests were conducted at a total enthalpy and pressure corresponding to Mach 5 flight at a dynamic pressure of 734 psf. The DFX is the largest engine ever tested in the CHSTF. Blockage, in terms of the projected engine area relative to the nozzle exit area, is 81% with the engine forebody leading edge aligned with the upper edge of the facility nozzle such that it ingests the nozzle boundary layer. The blockage increases to 95% with the engine forebody leading edge positioned 2 in. down in the core flow. Previous engines successfully tested in the CHSTF have had blockages of no more than 51%. Oil flow studies along with facility and engine pressure measurements were used to define flow behavior. These results guided modifications to existing aeroappliances and the design of new aeroappliances. These changes allowed fueled tests to be conducted without facility interaction effects in the data with the engine forebody leading edge positioned to ingest the facility nozzle boundary layer. Interaction effects were also reduced for tests with the engine forebody leading edge positioned 2 in. into the core flow, however some interaction effects were still evident in the engine data. A new shroud and diffuser have been designed with the goal of allowing fueled tests to be conducted with the engine forebody leading edge positioned in the core without facility interaction effects in the data. Evaluation tests of the new shroud and diffuser will be conducted once ongoing fueled engine tests have been completed.

Brightness and uniformity measurements of plastic scintillator tiles at the CERN H2 test beam

DOE PAGES

Chatrchyan, S.; Sirunyan, A. M.; Tumasyan, A.; ...

2018-01-05

Here, we study the light output, light collection efficiency and signal timing of a variety of organic scintillators that are being considered for the upgrade of the hadronic calorimeter of the CMS detector. The experimental data are collected at the H2 test-beam area at CERN, using a 150 GeV muon beam. In particular, we investigate the usage of over-doped and green-emitting plastic scintillators, two solutions that have not been extensively considered. We present a study of the energy distribution in plastic-scintillator tiles, the hit efficiency as a function of the hit position, and a study of the signal timing formore » blue and green scintillators.« less

Brightness and uniformity measurements of plastic scintillator tiles at the CERN H2 test beam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chatrchyan, S.; Sirunyan, A. M.; Tumasyan, A.

Here, we study the light output, light collection efficiency and signal timing of a variety of organic scintillators that are being considered for the upgrade of the hadronic calorimeter of the CMS detector. The experimental data are collected at the H2 test-beam area at CERN, using a 150 GeV muon beam. In particular, we investigate the usage of over-doped and green-emitting plastic scintillators, two solutions that have not been extensively considered. We present a study of the energy distribution in plastic-scintillator tiles, the hit efficiency as a function of the hit position, and a study of the signal timing formore » blue and green scintillators.« less

Photoproduction of vector mesons in proton-proton ultraperipheral collisions at the CERN Large Hadron Collider

NASA Astrophysics Data System (ADS)

Xie, Ya-Ping; Chen, Xurong

2018-05-01

Photoproduction of vector mesons is computed with dipole model in proton-proton ultraperipheral collisions (UPCs) at the CERN Large Hadron Collider (LHC). The dipole model framework is employed in the calculations of vector mesons production in diffractive processes. Parameters of the bCGC model are refitted with the latest inclusive deep inelastic scattering experimental data. Employing the bCGC model and boosted Gaussian light-cone wave function for vector mesons, we obtain the prediction of rapidity distributions of J/ψ and ψ(2s) mesons in proton-proton ultraperipheral collisions at the LHC. The predictions give a good description of the experimental data of LHCb. Predictions of ϕ and ω mesons are also evaluated in this paper.

Black holes in many dimensions at the CERN Large Hadron Collider: testing critical string theory.

PubMed

Hewett, JoAnne L; Lillie, Ben; Rizzo, Thomas G

2005-12-31

We consider black hole production at the CERN Large Hadron Collider (LHC) in a generic scenario with many extra dimensions where the standard model fields are confined to a brane. With approximately 20 dimensions the hierarchy problem is shown to be naturally solved without the need for large compactification radii. We find that in such a scenario the properties of black holes can be used to determine the number of extra dimensions, . In particular, we demonstrate that measurements of the decay distributions of such black holes at the LHC can determine if is significantly larger than 6 or 7 with high confidence and thus can probe one of the critical properties of string theory compactifications.

Evolution of optical fibre cabling components at CERN: Performance and technology trends analysis

NASA Astrophysics Data System (ADS)

Shoaie, Mohammad Amin; Meroli, Stefano; Machado, Simao; Ricci, Daniel

2018-05-01

CERN optical fibre infrastructure has been growing constantly over the past decade due to ever increasing connectivity demands. The provisioning plan and fibre installation of this vast laboratory is performed by Fibre Optics and Cabling Section at Engineering Department. In this paper we analyze the procurement data for essential fibre cabling components during a five-year interval to extract the existing trends and anticipate future directions. The analysis predicts high contribution of LC connector and an increasing usage of multi-fibre connectors. It is foreseen that single-mode fibres become the main fibre type for mid and long-range installations while air blowing would be the major installation technique. Performance assessment of various connectors shows that the expanded beam ferrule is favored for emerging on-board optical interconnections thanks to its scalable density and stable return-loss.

42 CFR 440.140 - Inpatient hospital services, nursing facility services, and intermediate care facility services...

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 4 2012-10-01 2012-10-01 false Inpatient hospital services, nursing facility... Definitions § 440.140 Inpatient hospital services, nursing facility services, and intermediate care facility... under section 1903(i)(4) of the Act and subpart H of part 456 of this chapter. (b) Nursing facility...

42 CFR 440.140 - Inpatient hospital services, nursing facility services, and intermediate care facility services...

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 4 2011-10-01 2011-10-01 false Inpatient hospital services, nursing facility... Definitions § 440.140 Inpatient hospital services, nursing facility services, and intermediate care facility... section 1903(i)(4) of the Act and subpart H of part 456 of this chapter. (b) Nursing facility services...

42 CFR 440.140 - Inpatient hospital services, nursing facility services, and intermediate care facility services...

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 4 2014-10-01 2014-10-01 false Inpatient hospital services, nursing facility... Definitions § 440.140 Inpatient hospital services, nursing facility services, and intermediate care facility... under section 1903(i)(4) of the Act and subpart H of part 456 of this chapter. (b) Nursing facility...

42 CFR 440.140 - Inpatient hospital services, nursing facility services, and intermediate care facility services...

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 4 2010-10-01 2010-10-01 false Inpatient hospital services, nursing facility... Definitions § 440.140 Inpatient hospital services, nursing facility services, and intermediate care facility... section 1903(i)(4) of the Act and subpart H of part 456 of this chapter. (b) Nursing facility services...

42 CFR 440.140 - Inpatient hospital services, nursing facility services, and intermediate care facility services...

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 4 2013-10-01 2013-10-01 false Inpatient hospital services, nursing facility... Definitions § 440.140 Inpatient hospital services, nursing facility services, and intermediate care facility... under section 1903(i)(4) of the Act and subpart H of part 456 of this chapter. (b) Nursing facility...

ROYAL PALMLINED WALK TO FACILITY 1041 (QUARTERS J) WITH FACILITY ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

ROYAL PALM-LINED WALK TO FACILITY 1041 (QUARTERS J) WITH FACILITY 1040 (QUARTERS 1) TO LEFT. TAKEN AT CORNER OF HALE ALII AVENUE AND EIGHTH STREET. VIEW FACING EAST. - U.S. Naval Base, Pearl Harbor, Naval Housing Area Hale Alii, Hale Alii Avenue, Eighth Street, & Avenue D, Pearl City, Honolulu County, HI

Measurement of the (33)S(n,α) cross-section at n_TOF(CERN): Applications to BNCT.

PubMed

Sabaté-Gilarte, Marta; Praena, Javier; Porras, Ignacio; Quesada, José Manuel; Mastinu, Pierfrancesco

2016-01-01

The main purpose of this work is to present a new (n,α) cross-section measurement for a stable isotope of sulfur, (33)S, in order to solve existing discrepancies. (33)S has been studied as a cooperating target for Boron Neutron Capture Therapy (BNCT) because of its large (n,α) cross-section in the epithermal neutron energy range, the most suitable one for BNCT. Although the most important evaluated databases, such as ENDF, do not show any resonances in the cross-section, experimental measurements which provided data from 10 keV to 1 MeV showed that the lowest-lying and strongest resonance of (33)S(n,α) cross-section occurs at 13.5 keV. Nevertheless, the set of resonance parameters that describe such resonance shows important discrepancies (more than a factor of 2) between them. A new measurement of the (33)S(n,α)(30)Si reaction cross-section was proposed to the ISOLDE and Neutron Time-of-Flight Experiments Committee of CERN. It was performed at n_TOF(CERN) in 2012 using MicroMegas detectors. In this work, we will present a brief overview of the experiment as well as preliminary results of the data analysis in the neutron energy range from thermal to 100 keV. These results will be taken into account to calculate the kerma-fluence factors corresponding to (33)S in addition to (10)B and those of a standard four-component ICRU tissue. MCNP simulations of the deposited dose, including our experimental data, shows an important kerma rate enhancement at the surface of the tissue, mainly due to the presence of (33)S.

Wake Shield Facility Modal Survey Test in Vibration Acoustic Test Facility

NASA Image and Video Library

1991-10-09

Astronaut Ronald M. Sega stands beside the University of Houston's Wake Shield Facility before it undergoes a Modal Survey Test in the Vibration and Acoustic Test Facility Building 49, prior to being flown on space shuttle mission STS-60.

48 CFR 1830.7002 - Facilities capital employed for facilities under construction.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Facilities capital employed for facilities under construction. 1830.7002 Section 1830.7002 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING...

EPA Facility Registry System (FRS): NEPT

EPA Pesticide Factsheets

This web feature service contains location and facility identification information from EPA's Facility Registry System (FRS) for the subset of facilities that link to the National Environmental Performance Track (NEPT) Program dataset. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. Additional information on FRS is available at the EPA website https://www.epa.gov/enviro/facility-registry-service-frs

EPA Facility Registry Service (FRS): NEI

EPA Pesticide Factsheets

This web feature service contains location and facility identification information from EPA's Facility Registry Service (FRS) for the subset of facilities that link to the National Emissions Inventory (NEI) Program dataset. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. Additional information on FRS is available at the EPA website https://www.epa.gov/enviro/facility-registry-service-frs

Biotechnology Facility: An ISS Microgravity Research Facility

NASA Technical Reports Server (NTRS)

Gonda, Steve R.; Tsao, Yow-Min

2000-01-01

The International Space Station (ISS) will support several facilities dedicated to scientific research. One such facility, the Biotechnology Facility (BTF), is sponsored by the Microgravity Sciences and Applications Division (MSAD) and developed at NASA's Johnson Space Center. The BTF is scheduled for delivery to the ISS via Space Shuttle in April 2005. The purpose of the BTF is to provide: (1) the support structure and integration capabilities for the individual modules in which biotechnology experiments will be performed, (2) the capability for human-tended, repetitive, long-duration biotechnology experiments, and (3) opportunities to perform repetitive experiments in a short period by allowing continuous access to microgravity. The MSAD has identified cell culture and tissue engineering, protein crystal growth, and fundamentals of biotechnology as areas that contain promising opportunities for significant advancements through low-gravity experiments. The focus of this coordinated ground- and space-based research program is the use of the low-gravity environment of space to conduct fundamental investigations leading to major advances in the understanding of basic and applied biotechnology. Results from planned investigations can be used in applications ranging from rational drug design and testing, cancer diagnosis and treatments and tissue engineering leading to replacement tissues.

48 CFR 1830.7001 - Facilities capital employed for facilities in use.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Facilities capital employed for facilities in use. 1830.7001 Section 1830.7001 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION...

Associations between Moderate-to-Vigorous Physical Activity and Neighbourhood Recreational Facilities: The Features of the Facilities Matter

PubMed Central

Lee, Ka Yiu; Lee, Paul H.; Macfarlane, Duncan

2014-01-01

Objectives: To examine the associations between objectively-assessed moderate-to-vigorous physical activity (MVPA) and perceived/objective measures of neighbourhood recreational facilities categorized into indoor or outdoor, public, residential or commercial facilities. The associations between facility perceptions and objectively-assessed numbers of recreational facilities were also examined. Method: A questionnaire was used on 480 adults to measure local facility perceptions, with 154 participants wearing ActiGraph accelerometers for ≥4 days. The objectively-assessed number of neighbourhood recreational facilities were examined using direct observations and Geographical Information System data. Results: Both positive and negative associations were found between MVPA and perceived/objective measures of recreational facilities. Some associations depended on whether the recreational facilities were indoor or outdoor, public or residential facilities. The objectively-assessed number of most public recreational facilities was associated with the corresponding facility perceptions, but the size of effect was generally lower than for residential recreational facilities. Conclusions: The objectively-assessed number of residential outdoor table tennis courts and public indoor swimming pools, the objectively-assessed presence of tennis courts and swimming pools, and the perceived presence of bike lanes and swimming pools were positive determinants of MVPA. It is suggested to categorize the recreational facilities into smaller divisions in order to identify unique associations with MVPA. PMID:25485980

33 CFR 125.07 - Waterfront facility.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Waterfront facility. 125.07...) WATERFRONT FACILITIES IDENTIFICATION CREDENTIALS FOR PERSONS REQUIRING ACCESS TO WATERFRONT FACILITIES OR VESSELS § 125.07 Waterfront facility. The term waterfront facility as used in this subchapter, means all...

Investigating walking environments in and around assisted living facilities: a facility visit study.

PubMed

Lu, Zhipeng

2010-01-01

This study explores assisted living residents' walking behaviors, locations where residents prefer to walk, and walking environments in and around assisted living facilities. Regular walking is beneficial to older adults' physical and psychological health. Yet frail older residents in assisted living are usually too sedentary to achieve these benefits. The physical environment plays an important role in promoting physical activity. However, there is little research exploring this relationship in assisted living settings. The researcher visited 34 assisted living facilities in a major Texas city. Methods included walk-through observation with the Assisted Living Facility Walking Environment Checklist, and interviews with administrators by open- and close-ended questions. The data from 26 facilities were analyzed using descriptive statistics (for quantitative data) and content analysis (for qualitative data). The results indicate that (a) residents were walking both indoors and outdoors for exercise or other purposes (e.g., going to destinations); (b) assisted living facility planning and design details-such as neighborhood sidewalk conditions, facility site selection, availability of seating, walking path configuration (e.g., looped/nonlooped path), amount of shading along the path, presence of handrails, existence of signage, etc.-may influence residents' walking behaviors; and (c) current assisted living facilities need improvement in all aspects to make their environments more walkable for residents. Findings of the study provide recommendations for assisted living facilities to improve the walkability of environments and to create environmental interventions to promote regular walking among their residents. This study also implies several directions for future research.

33 CFR 154.1216 - Facility classification.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Facility classification. 154.1216... Vegetable Oils Facilities § 154.1216 Facility classification. (a) The Coast Guard classifies facilities that... classification of a facility that handles, stores, or transports animal fats or vegetable oils. The COTP may...

33 CFR 154.1216 - Facility classification.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Facility classification. 154.1216... Vegetable Oils Facilities § 154.1216 Facility classification. (a) The Coast Guard classifies facilities that... classification of a facility that handles, stores, or transports animal fats or vegetable oils. The COTP may...

33 CFR 154.1216 - Facility classification.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Facility classification. 154.1216... Vegetable Oils Facilities § 154.1216 Facility classification. (a) The Coast Guard classifies facilities that... classification of a facility that handles, stores, or transports animal fats or vegetable oils. The COTP may...

10 CFR 611.206 - Existing facilities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Existing facilities. 611.206 Section 611.206 Energy... PROGRAM Facility/Funding Awards § 611.206 Existing facilities. The Secretary shall, in making awards to those manufacturers that have existing facilities, give priority to those facilities that are oldest or...

33 CFR 154.1216 - Facility classification.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Vegetable Oils Facilities § 154.1216 Facility classification. (a) The Coast Guard classifies facilities that handle, store, or transport animal fats or vegetable oils as “substantial harm” facilities because they... classification of a facility that handles, stores, or transports animal fats or vegetable oils. The COTP may...

33 CFR 154.1216 - Facility classification.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Vegetable Oils Facilities § 154.1216 Facility classification. (a) The Coast Guard classifies facilities that handle, store, or transport animal fats or vegetable oils as “substantial harm” facilities because they... classification of a facility that handles, stores, or transports animal fats or vegetable oils. The COTP may...

RAND Workshop on Antiproton Science and Technology, Annotated Executive Summary. (October 6-9, 1987)

DTIC Science & Technology

1988-10-01

parity violation to condensed matter . A number of near-term important applications are possible using the source and portable storage devices...from charge parity violation studies to condensed matter studies. -vi - The CERN/LEAR facility will continue to only scratch the surface of important...technology programs. These technology programs include possible small tools to study extreme states of matter ;, a propulsion test facility for

9 CFR 3.51 - Facilities, indoor.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Facilities, indoor. 3.51 Section 3.51... Facilities and Operating Standards § 3.51 Facilities, indoor. (a) Heating. Indoor housing facilities for rabbits need not be heated. (b) Ventilation. Indoor housing facilities for rabbits shall be adequately...

18 CFR 1317.410 - Comparable facilities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Comparable facilities... facilities. A recipient may provide separate toilet, locker room, and shower facilities on the basis of sex, but such facilities provided for students of one sex shall be comparable to such facilities provided...

Service quality in contracted facilities.

PubMed

Rabbani, Fauziah; Pradhan, Nousheen Akber; Zaidi, Shehla; Azam, Syed Iqbal; Yousuf, Farheen

2015-01-01

The purpose of this paper is to explore the readiness of contracted and non-contracted first-level healthcare facilities in Pakistan to deliver quality maternal and neonatal health (MNH) care. A balanced scorecard (BSC) was used as the assessment framework. Using a cross-sectional study design, two rural health centers (RHCs) contracted out to Aga Khan Health Service, Pakistan were compared with four government managed RHCs. A BSC was designed to assess RHC readiness to deliver good quality MNH care. In total 20 indicators were developed, representing five BSC domains: health facility functionality, service provision, staff capacity, staff and patient satisfaction. Validated data collection tools were used to collect information. Pearson χ2, Fisher's Exact and the Mann-Whitney tests were applied as appropriate to detect significant service quality differences among the two facilities. Contracted facilities were generally found to be better than non-contracted facilities in all five BSC domains. Patients' inclination for facility-based delivery at contracted facilities was, however, significantly higher than non-contracted facilities (80 percent contracted vs 43 percent non-contracted, p=0.006). The study shows that contracting out initiatives have the potential to improve MNH care. This is the first study to compare MNH service delivery quality across contracted and non-contracted facilities using BSC as the assessment framework.

EPA Facility Registry Service (FRS): TRI

EPA Pesticide Factsheets

This web feature service contains location and facility identification information from EPA's Facility Registry Service (FRS) for the subset of facilities that link to the Toxic Release Inventory (TRI) System. TRI is a publicly available EPA database reported annually by certain covered industry groups, as well as federal facilities. It contains information about more than 650 toxic chemicals that are being used, manufactured, treated, transported, or released into the environment, and includes information about waste management and pollution prevention activities. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to TRI facilities once the TRI data has been integrated into the FRS database. Additional information on FRS is available at the EPA website https://www.epa.gov/enviro/facility-registry-service-frs.

Facility Design Considerations.

ERIC Educational Resources Information Center

Chase, William W.

1967-01-01

Increasing need for vocational education under the impetus of federal aid is generating a demand for vocational teaching facilities. Factors to be considered in planning these facilities inclued--(1) site development, (2) program needs, (3) administrative considerations, (4) environmental controls. (5) mechanical systems, and (6) area and space…

The ISOLDE LEGO® robot: building interest in frontier research

NASA Astrophysics Data System (ADS)

Elias Cocolios, Thomas; Lynch, Kara M.; Nichols, Emma

2017-07-01

An outreach programme centred around nuclear physics making use of a LEGO® Mindstorm® kit is presented. It consists of a presentation given by trained undergraduate students as science ambassadors followed by a workshop where the target audience programs the LEGO® Mindstorm® robots to familiarise themselves with the concepts in an interactive and exciting way. This programme has been coupled with the CERN-ISOLDE 50th anniversary and the launch of the CERN-MEDICIS facility in Geneva, Switzerland. The modular aspect of the programme readily allows its application to other topics.

EPA Facility Registry Service (FRS): CAMDBS

EPA Pesticide Factsheets

This web feature service contains location and facility identification information from EPA's Facility Registry Service (FRS) for the subset of facilities that link to the Clean Air Markets Division Business System (CAMDBS). Administered by the EPA Clean Air Markets Division, within the Office of Air and Radiation, CAMDBS supports the implementation of market-based air pollution control programs, including the Acid Rain Program and regional programs designed to reduce the transport of ozone. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to CAMDBS facilities once the CAMDBS data has been integrated into the FRS database. Additional information on FRS is available at the EPA website https://www.epa.gov/enviro/facility-registry-service-frs.

EPA Facility Registry Service (FRS): RCRA

EPA Pesticide Factsheets

This web feature service contains location and facility identification information from EPA's Facility Registry Service (FRS) for the subset of hazardous waste facilities that link to the Resource Conservation and Recovery Act Information System (RCRAInfo). EPA's comprehensive information system in support of the Resource Conservation and Recovery Act (RCRA) of 1976 and the Hazardous and Solid Waste Amendments (HSWA) of 1984, RCRAInfo tracks many types of information about generators, transporters, treaters, storers, and disposers of hazardous waste. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to RCRAInfo hazardous waste facilities once the RCRAInfo data has been integrated into the FRS database. Additional information on FRS is available at the EPA website https://www.epa.gov/enviro/facility-registry-service-frs

9 CFR 3.27 - Facilities, outdoor.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Pigs and Hamsters Facilities and Operating Standards § 3.27 Facilities, outdoor. (a) Hamsters shall not be housed in outdoor facilities. (b) Guinea pigs shall not be housed in outdoor facilities unless...

9 CFR 3.27 - Facilities, outdoor.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Pigs and Hamsters Facilities and Operating Standards § 3.27 Facilities, outdoor. (a) Hamsters shall not be housed in outdoor facilities. (b) Guinea pigs shall not be housed in outdoor facilities unless...

9 CFR 3.27 - Facilities, outdoor.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Pigs and Hamsters Facilities and Operating Standards § 3.27 Facilities, outdoor. (a) Hamsters shall not be housed in outdoor facilities. (b) Guinea pigs shall not be housed in outdoor facilities unless...

9 CFR 3.27 - Facilities, outdoor.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Pigs and Hamsters Facilities and Operating Standards § 3.27 Facilities, outdoor. (a) Hamsters shall not be housed in outdoor facilities. (b) Guinea pigs shall not be housed in outdoor facilities unless...

DOE Office of Scientific and Technical Information (OSTI.GOV)

campbell, myron

To create a research and study abroad program that would allow U.S. undergraduate students access to the world-leading research facilities at the European Organization for Nuclear Research (CERN), the World Health Organization, various operations of the United Nations and other international organizations based in Geneva.The proposal is based on the unique opportunities currently existing in Geneva. The Large Hadron Collider (LHC) is now operational at CERN, data are being collected, and research results are already beginning to emerge. At the same time, a related reduction of activity at U.S. facilities devoted to particle physics is expected. In addition, the U.S.more » higher-education community has an ever-increasing focus on international organizations dealing with world health pandemics, arms control and human rights, a nexus also centered in Geneva.« less

Science Facilities Bibliography.

ERIC Educational Resources Information Center

National Science Foundation, Washington, DC.

A bibliographic collection on science buildings and facilities is cited with many different reference sources for those concerned with the design, planning, and layout of science facilities. References are given covering a broad scope of information on--(1) physical plant planning, (2) management and safety, (3) building type studies, (4) design…

Mir training Facility view

NASA Image and Video Library

1995-02-22

S95-04319 (22 Feb 1995) --- The neutral buoyancy facility at the Gagarin Cosmonaut Training Center in Star City, Russia, is used for underwater training for missions aboard the Russian Mir Space Station. The facility is similar to NASA's Weightless Environment Training Facility (WET-F) at the Johnson Space Center (JSC) in Houston, Texas, and the Neutral Buoyancy Simulator (NBS) at the Marshall Space Flight Center (MSFC) in Huntsville, Alabama.

An inventory of aeronautical ground research facilities. Volume 4: Engineering flight simulation facilities

NASA Technical Reports Server (NTRS)

Pirrello, C. J.; Hardin, R. D.; Capelluro, L. P.; Harrison, W. D.

1971-01-01

The general purpose capabilities of government and industry in the area of real time engineering flight simulation are discussed. The information covers computer equipment, visual systems, crew stations, and motion systems, along with brief statements of facility capabilities. Facility construction and typical operational costs are included where available. The facilities provide for economical and safe solutions to vehicle design, performance, control, and flying qualities problems of manned and unmanned flight systems.

20 CFR 416.1023 - Facilities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Facilities. 416.1023 Section 416.1023... Facilities. (a) Space, equipment, supplies, and other services. Subject to appropriate Federal funding, the... and prompt disability determinations. (b) Location of facilities. Subject to appropriate Federal...

Measurement of the 33S(n,α) cross-section at n_TOF(CERN): Applications to BNCT

PubMed Central

Sabaté-Gilarte, Marta; Praena, Javier; Porras, Ignacio; Quesada, José Manuel; Mastinu, Pierfrancesco

2016-01-01

Aim The main purpose of this work is to present a new (n,α) cross-section measurement for a stable isotope of sulfur, 33S, in order to solve existing discrepancies. Background 33S has been studied as a cooperating target for Boron Neutron Capture Therapy (BNCT) because of its large (n,α) cross-section in the epithermal neutron energy range, the most suitable one for BNCT. Although the most important evaluated databases, such as ENDF, do not show any resonances in the cross-section, experimental measurements which provided data from 10 keV to 1 MeV showed that the lowest-lying and strongest resonance of 33S(n,α) cross-section occurs at 13.5 keV. Nevertheless, the set of resonance parameters that describe such resonance shows important discrepancies (more than a factor of 2) between them. Materials and methods A new measurement of the 33S(n,α)30Si reaction cross-section was proposed to the ISOLDE and Neutron Time-of-Flight Experiments Committee of CERN. It was performed at n_TOF(CERN) in 2012 using MicroMegas detectors. Results In this work, we will present a brief overview of the experiment as well as preliminary results of the data analysis in the neutron energy range from thermal to 100 keV. These results will be taken into account to calculate the kerma-fluence factors corresponding to 33S in addition to 10B and those of a standard four-component ICRU tissue. Conclusions MCNP simulations of the deposited dose, including our experimental data, shows an important kerma rate enhancement at the surface of the tissue, mainly due to the presence of 33S. PMID:26933393

Upper limits of the proton magnetic form factor in the time-like region from p¯p--> e+e- at the CERN-ISR

NASA Astrophysics Data System (ADS)

Baglin, C.; Baird, S.; Bassompierre, G.; Borreani, G.; Brient, J. C.; Broll, C.; Brom, J. M.; Bugge, L.; Buran, T.; Burq, J. P.; Bussière, A.; Buzzo, A.; Cester, R.; Chemarin, M.; Chevallier, M.; Escoubes, B.; Fay, J.; Ferroni, S.; Gracco, V.; Guillaud, J. P.; Khan-Aronsen, E.; Kirsebom, K.; Ille, B.; Lambert, M.; Leistam, L.; Lundby, A.; Macri, M.; Marchetto, F.; Mattera, L.; Menichetti, E.; Mouellic, B.; Pastrone, N.; Petrillo, L.; Pia, M. G.; Poulet, M.; Pozzo, A.; Rinaudo, G.; Santroni, A.; Severi, M.; Skjevling, G.; Stapnes, S.; Stugu, B.; Tomasini, F.; Valbusa, U.

1985-11-01

From the measurement of e+e- pairs from the reaction p¯p-->e+e- at the CERN-ISR, using an antiproton beam and a hydrogen jet target, we derived upper limits for the proton magnetic form factor in the time-like region at Q2⋍8.9(GeV/c)2 and Q2⋍12.5(GeV/c)2.

Facilities for US Radioastronomy.

ERIC Educational Resources Information Center

Thaddeus, Patrick

1982-01-01

Discusses major developments in radioastronomy since 1945. Topics include proposed facilities, very-long-baseline interferometric array, millimeter-wave telescope, submillimeter-wave telescope, and funding for radioastronomy facilities and projects. (JN)

Sanford Underground Research Facility - The United State's Deep Underground Research Facility

NASA Astrophysics Data System (ADS)

Vardiman, D.

2012-12-01

The 2.5 km deep Sanford Underground Research Facility (SURF) is managed by the South Dakota Science and Technology Authority (SDSTA) at the former Homestake Mine site in Lead, South Dakota. The US Department of Energy currently supports the development of the facility using a phased approach for underground deployment of experiments as they obtain an advanced design stage. The geology of the Sanford Laboratory site has been studied during the 125 years of operations at the Homestake Mine and more recently as part of the preliminary geotechnical site investigations for the NSF's Deep Underground Science and Engineering Laboratory project. The overall geology at DUSEL is a well-defined stratigraphic sequence of schist and phyllites. The three major Proterozoic units encountered in the underground consist of interbedded schist, metasediments, and amphibolite schist which are crosscut by Tertiary rhyolite dikes. Preliminary geotechnical site investigations included drift mapping, borehole drilling, borehole televiewing, in-situ stress analysis, laboratory analysis of core, mapping and laser scanning of new excavations, modeling and analysis of all geotechnical information. The investigation was focused upon the determination if the proposed site rock mass could support the world's largest (66 meter diameter) deep underground excavation. While the DUSEL project has subsequently been significantly modified, these data are still available to provide a baseline of the ground conditions which may be judiciously extrapolated throughout the entire Proterozoic rock assemblage for future excavations. Recommendations for facility instrumentation and monitoring were included in the preliminary design of the DUSEL project design and include; single and multiple point extensometers, tape extensometers and convergence measurements (pins), load cells and pressure cells, smart cables, inclinometers/Tiltmeters, Piezometers, thermistors, seismographs and accelerometers, scanners (laser

EPA Facility Registry System (FRS): NCES

EPA Pesticide Factsheets

This web feature service contains location and facility identification information from EPA's Facility Registry System (FRS) for the subset of facilities that link to the National Center for Education Statistics (NCES). The primary federal database for collecting and analyzing data related to education in the United States and other Nations, NCES is located in the U.S. Department of Education, within the Institute of Education Sciences. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA00e2??s national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to NCES school facilities once the NCES data has been integrated into the FRS database. Additional information on FRS is available at the EPA website http://www.epa.gov/enviro/html/fii/index.html.

High Energy Physics Research with the CMS Experiment at CERN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hanson, Gail G.

2013-05-31

The highlight of our last budget period, June 1, 2010, to May 31, 2013, was the discovery of the Higgs boson by the ATLAS and CMS experiments at the CERN Large Hadron Collider (LHC), announced on July 4, 2012, and for which François Englert and Peter Higgs were awarded the 2013 Nobel Prize in Physics on October 8, 2013. The Higgs boson was postulated in 1964 to explain how elementary particles obtain mass and was the missing piece of the Standard Model. However, the Standard Model does not describe everything that we know. There are many unanswered questions, such asmore » how can the Higgs boson have the mass that we have observed, are there more Higgs bosons, why is there more matter than antimatter, and what is the invisible dark matter, which constitutes about 85% of the matter in the universe. Our group played a significant role in the discovery of the Higgs boson and in subsequent analyses. We also carried out searches for new physics, in ways that could help elucidate some of the remaining questions. Our role in the CMS detector focused on the Tracker, a silicon strip outer tracker and pixel inner tracker.« less

Capital Ideas for Facilities Management.

ERIC Educational Resources Information Center

Golding, Stephen T.; Gordon, Janet; Gravina, Arthur

2001-01-01

Asserting that just like chief financial officers, higher education facilities specialists must maximize the long-term performance of assets under their care, describes strategies for strategic facilities management. Discusses three main approaches to facilities management (insourcing, cosourcing, and outsourcing) and where boards of trustees fit…

9 CFR 351.10 - Facilities.

Code of Federal Regulations, 2014 CFR

2014-01-01

... CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Facilities and Operations § 351.10 Facilities. (a) Facilities for the preparation, identification, and storage of the technical animal fat to be... maintain the identity of certified technical animal fats and materials used in their preparation, and...

9 CFR 351.10 - Facilities.

Code of Federal Regulations, 2012 CFR

2012-01-01

... CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Facilities and Operations § 351.10 Facilities. (a) Facilities for the preparation, identification, and storage of the technical animal fat to be... maintain the identity of certified technical animal fats and materials used in their preparation, and...

9 CFR 351.10 - Facilities.

Code of Federal Regulations, 2011 CFR

2011-01-01

... CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Facilities and Operations § 351.10 Facilities. (a) Facilities for the preparation, identification, and storage of the technical animal fat to be... maintain the identity of certified technical animal fats and materials used in their preparation, and...

9 CFR 351.10 - Facilities.

Code of Federal Regulations, 2013 CFR

2013-01-01

... CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Facilities and Operations § 351.10 Facilities. (a) Facilities for the preparation, identification, and storage of the technical animal fat to be... maintain the identity of certified technical animal fats and materials used in their preparation, and...

20 CFR 404.1623 - Facilities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Facilities. 404.1623 Section 404.1623...- ) Determinations of Disability Administrative Responsibilities and Requirements § 404.1623 Facilities. (a) Space... determinations. (b) Location of facilities. Subject to appropriate Federal funding, the State will determine the...

Thomas Jefferson National Accelerator Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grames, Joseph; Higinbotham, Douglas; Montgomery, Hugh

The Thomas Jefferson National Accelerator Facility (Jefferson Lab) in Newport News, Virginia, USA, is one of ten national laboratories under the aegis of the Office of Science of the U.S. Department of Energy (DOE). It is managed and operated by Jefferson Science Associates, LLC. The primary facility at Jefferson Lab is the Continuous Electron Beam Accelerator Facility (CEBAF) as shown in an aerial photograph in Figure 1. Jefferson Lab was created in 1984 as CEBAF and started operations for physics in 1995. The accelerator uses superconducting radio-frequency (srf) techniques to generate high-quality beams of electrons with high-intensity, well-controlled polarization. Themore » technology has enabled ancillary facilities to be created. The CEBAF facility is used by an international user community of more than 1200 physicists for a program of exploration and study of nuclear, hadronic matter, the strong interaction and quantum chromodynamics. Additionally, the exceptional quality of the beams facilitates studies of the fundamental symmetries of nature, which complement those of atomic physics on the one hand and of high-energy particle physics on the other. The facility is in the midst of a project to double the energy of the facility and to enhance and expand its experimental facilities. Studies are also pursued with a Free-Electron Laser produced by an energy-recovering linear accelerator.« less

National facilities study. Volume 2: Task group on aeronautical research and development facilities report

NASA Technical Reports Server (NTRS)

1994-01-01

The Task Group on Aeronautics R&D Facilities examined the status and requirements for aeronautics facilities against the competitive need. Emphasis was placed on ground-based facilities for subsonic, supersonic and hypersonic aerodynamics, and propulsion. Subsonic and transonic wind tunnels were judged to be most critical and of highest priority. Results of the study are presented.

FEDERAL FACILITIES IN EPA REGION 6

EPA Science Inventory

Locations of federal facilities in EPA Region 6. Facilities from the Corps of Engineers, Veterans Administration, Army, Navy, Air National Guard, etc. are included. This is not a complete set of facilities. The facilities included are only those with value added locations used in...

9 CFR 3.27 - Facilities, outdoor.

Code of Federal Regulations, 2010 CFR

2010-01-01

... WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Guinea Pigs and Hamsters Facilities and Operating Standards § 3.27 Facilities, outdoor. (a) Hamsters shall not be housed in outdoor facilities. (b) Guinea pigs shall not be housed in outdoor facilities unless...

Landscape of supersymmetric particle mass hierarchies and their signature space at the CERN Large Hadron Collider.

PubMed

Feldman, Daniel; Liu, Zuowei; Nath, Pran

2007-12-21

The minimal supersymmetric standard model with soft breaking has a large landscape of supersymmetric particle mass hierarchies. This number is reduced significantly in well-motivated scenarios such as minimal supergravity and alternatives. We carry out an analysis of the landscape for the first four lightest particles and identify at least 16 mass patterns, and provide benchmarks for each. We study the signature space for the patterns at the CERN Large Hadron Collider by analyzing the lepton+ (jet> or =2) + missing P{T} signals with 0, 1, 2, and 3 leptons. Correlations in missing P{T} are also analyzed. It is found that even with 10 fb{-1} of data a significant discrimination among patterns emerges.

Spacelab Data Processing Facility

NASA Technical Reports Server (NTRS)

1983-01-01

The capabilities of the Spacelab Data Processing Facility (SPDPF) are highlighted. The capturing, quality monitoring, processing, accounting, and forwarding of vital Spacelab data to various user facilities around the world are described.

Plant Habitat Facility Clean

NASA Image and Video Library

2018-03-12

iss055e001931 (Mar. 12, 2018) --- Dwarf wheat plants during routine cleaning in the Advanced Plant Habitat Facility, a facility to conduct plant bioscience research on the International Space Stations (ISS).

7 CFR 51.57 - Facilities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false Facilities. 51.57 Section 51.57 Agriculture... Requirements for Plants Operating Under Continuous Inspection on A Contract Basis § 51.57 Facilities. Each packing plant shall be equipped with adequate sanitary facilities and accommodations, including but not...

10 CFR 55.46 - Simulation facilities.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Simulation facilities. 55.46 Section 55.46 Energy NUCLEAR... Simulation facilities. (a) General. This section addresses the use of a simulation facility for the... applicants for operator and senior operator licenses. (b) Commission-approved simulation facilities and...

10 CFR 55.46 - Simulation facilities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Simulation facilities. 55.46 Section 55.46 Energy NUCLEAR... Simulation facilities. (a) General. This section addresses the use of a simulation facility for the... applicants for operator and senior operator licenses. (b) Commission-approved simulation facilities and...

10 CFR 55.46 - Simulation facilities.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Simulation facilities. 55.46 Section 55.46 Energy NUCLEAR... Simulation facilities. (a) General. This section addresses the use of a simulation facility for the... applicants for operator and senior operator licenses. (b) Commission-approved simulation facilities and...

10 CFR 55.46 - Simulation facilities.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Simulation facilities. 55.46 Section 55.46 Energy NUCLEAR... Simulation facilities. (a) General. This section addresses the use of a simulation facility for the... applicants for operator and senior operator licenses. (b) Commission-approved simulation facilities and...

10 CFR 55.46 - Simulation facilities.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Simulation facilities. 55.46 Section 55.46 Energy NUCLEAR... Simulation facilities. (a) General. This section addresses the use of a simulation facility for the... applicants for operator and senior operator licenses. (b) Commission-approved simulation facilities and...

Facilities Performance Indicators Report, 2008-09

ERIC Educational Resources Information Center

Hills, Christina, Ed.

2010-01-01

This paper features another expanded Web-based Facilities Performance Indicators Report (FPI). The purpose of APPA's Facilities Performance Indicators is to provide a representative set of statistics about facilities in educational institutions. The 2008-09 iteration of the Web-based Facilities Performance Indicators Survey was posted and…

44 CFR 331.5 - Production facilities.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Production facilities. 331.5... AND FACILITIES IN LABOR SURPLUS AREAS § 331.5 Production facilities. All Federal departments and... production facilities, including expansion, to the extent that such selection is consistent with existing law...

28 CFR 54.410 - Comparable facilities.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Comparable facilities. 54.410 Section 54... in Education Programs or Activities Prohibited § 54.410 Comparable facilities. A recipient may provide separate toilet, locker room, and shower facilities on the basis of sex, but such facilities...

Facility Management's Role in Organizational Sustainability

ERIC Educational Resources Information Center

Adams, Gregory K.

2013-01-01

Facility managers have questions about sustainability. How do an organization's physical facilities--its built environment--and the management of them, influence the sustainability of the organization or institution as a whole? How important is Facility Management (FM) to the overall sustainability profile of an organization? Facility managers…

Designing Facilities for Collaborative Operations

NASA Technical Reports Server (NTRS)

Norris, Jeffrey; Powell, Mark; Backes, Paul; Steinke, Robert; Tso, Kam; Wales, Roxana

2003-01-01

A methodology for designing operational facilities for collaboration by multiple experts has begun to take shape as an outgrowth of a project to design such facilities for scientific operations of the planned 2003 Mars Exploration Rover (MER) mission. The methodology could also be applicable to the design of military "situation rooms" and other facilities for terrestrial missions. It was recognized in this project that modern mission operations depend heavily upon the collaborative use of computers. It was further recognized that tests have shown that layout of a facility exerts a dramatic effect on the efficiency and endurance of the operations staff. The facility designs (for example, see figure) and the methodology developed during the project reflect this recognition. One element of the methodology is a metric, called effective capacity, that was created for use in evaluating proposed MER operational facilities and may also be useful for evaluating other collaboration spaces, including meeting rooms and military situation rooms. The effective capacity of a facility is defined as the number of people in the facility who can be meaningfully engaged in its operations. A person is considered to be meaningfully engaged if the person can (1) see, hear, and communicate with everyone else present; (2) see the material under discussion (typically data on a piece of paper, computer monitor, or projection screen); and (3) provide input to the product under development by the group. The effective capacity of a facility is less than the number of people that can physically fit in the facility. For example, a typical office that contains a desktop computer has an effective capacity of .4, while a small conference room that contains a projection screen has an effective capacity of around 10. Little or no benefit would be derived from allowing the number of persons in an operational facility to exceed its effective capacity: At best, the operations staff would be underutilized

21 CFR 606.40 - Facilities.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Facilities. 606.40 Section 606.40 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS CURRENT GOOD MANUFACTURING PRACTICE FOR BLOOD AND BLOOD COMPONENTS Plant and Facilities § 606.40 Facilities...

Systematic Planning for Educational Facilities.

ERIC Educational Resources Information Center

McGuffey, Carroll W.

This monograph provides a systematic approach to the problem of planning educational facilities. It first presents a conceptual framework for a general facilities planning and management system called Facilities Resource Allocation Management Evaluation System (FRAMES). The main components of FRAMES are identified as: (1) needs assessment, (2)…

14 CFR 142.15 - Facilities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Facilities. 142.15 Section 142.15... OTHER CERTIFICATED AGENCIES TRAINING CENTERS General § 142.15 Facilities. (a) An applicant for, or..., sanitation, and health codes; and (2) The facilities used for instruction are not routinely subject to...

21 CFR 606.40 - Facilities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Facilities. 606.40 Section 606.40 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS CURRENT GOOD MANUFACTURING PRACTICE FOR BLOOD AND BLOOD COMPONENTS Plant and Facilities § 606.40 Facilities...

Grid Facilities | Grid Modernization | NREL

Science.gov Websites

groundbreaking innovations and collaboration in grid research. Photo of the Energy Systems Integration Facility Energy Systems Integration Facility The Energy Systems Integration Facility is the nation's premier user Located in Boulder, Colorado, the National Wind Technology Center (NWTC) offers similar integration

Spin and model determination of Z‧ - boson in lepton pair production at CERN LHC

NASA Astrophysics Data System (ADS)

Tsytrinov, A. V.; Pankov, A. A.; Serenkova, I. A.; Bednyakov, V. A.

2017-12-01

Many new physics models predict production of heavy resonances in Drell-Yan channel and can be observed at the CERN LHC. If a new resonance is discovered as a peak in the dilepton invariant mass distribution at the LHC, the identification of its spin and couplings can be done by measuring production rates and angular distributions of the decay products. Here we discuss the spin-1 identification of Z‧-boson for a set of representative models (SSM, E6, LR, and ALR) against the spin-2 RS graviton resonance and a spin-0 sneutrino resonance with the same mass and producing the same number of events under the resonance peak. We use the center-edge asymmetry for spin identification, as well as the total dilepton production cross section for the distinguishing the considered Z‧-boson models from one another.

Accelerator Facilities for Radiation Research

NASA Technical Reports Server (NTRS)

Cucinotta, Francis A.

1999-01-01

HSRP Goals in Accelerator Use and Development are: 1.Need for ground-based heavy ion and proton facility to understand space radiation effects discussed most recently by NAS/NRC Report (1996). 2. Strategic Program Goals in facility usage and development: -(1) operation of AGS for approximately 600 beam hours/year; (2) operation of Loma Linda University (LLU) proton facility for approximately 400 beam hours/year; (3) construction of BAF facility; and (4) collaborative research at HIMAC in Japan and with other existing or potential international facilities. 3. MOA with LLU has been established to provide proton beams with energies of 40-250 important for trapped protons and solar proton events. 4. Limited number of beam hours available at Brookhaven National Laboratory's (BNL) Alternating Gradient Synchrotron (AGS).

49 CFR 25.410 - Comparable facilities.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 1 2011-10-01 2011-10-01 false Comparable facilities. 25.410 Section 25.410... Education Programs or Activities Prohibited § 25.410 Comparable facilities. A recipient may provide separate toilet, locker room, and shower facilities on the basis of sex, but such facilities provided for students...

42 CFR 136.110 - Facilities construction.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Facilities construction. 136.110 Section 136.110... Facilities and Services § 136.110 Facilities construction. In addition to other requirements of this subpart..., clinic, health station or quarters for housing personnel associated with such facilities, must in its...

Facilities Guidelines. North Carolina Public Schools.

ERIC Educational Resources Information Center

North Carolina State Dept. of Public Instruction, Raleigh.

The 1986 North Carolina Public School Facilities Standards were legislated in 1996 to become Facility Guidelines. A Public School Facilities Task Force was appointed to review and make revisions. These 1997 guidelines define and describe minimum facilities to ensure educational program appropriateness and long-term cost efficiency. They were…

30 CFR 57.20008 - Toilet facilities.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Toilet facilities. 57.20008 Section 57.20008....20008 Toilet facilities. (a) Toilet facilities shall be provided at locations that are compatible with the mine operations and that are readily accessible to mine personnel. (b) The facilities shall be...

36 CFR 13.166 - Temporary facilities.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Temporary facilities. 13.166... facilities. A temporary facility or structure directly and necessarily related to the taking of subsistence... facilities which shall be published annually in accordance with § 1.7 of this chapter. ...

Search for the 1P 1 charmonium state in overlinepp annihilations at the CERN intersecting storage rings

NASA Astrophysics Data System (ADS)

Baglin, C.; Baird, S.; Bassompierre, G.; Borreani, G.; Brient, J.-C.; Broll, C.; Brom, J.-M.; Bugge, L.; Buran, T.; Burq, J.-P.; Bussière, A.; Buzzo, A.; Cester, R.; Chemarin, M.; Chevallier, M.; Escoubes, B.; Fay, J.; Ferroni, S.; Gracco, V.; Guillaud, J.-P.; Khan-Aronsen, E.; Kirsebom, K.; Kylling, A.; Ille, B.; Lambert, M.; Leistam, L.; Lundby, A.; Macri, M.; Marchetto, F.; Menichetti, E.; Mörch, Ch.; Mouellic, B.; Olsen, D.; Pastrone, N.; Petrillo, L.; Pia, M. G.; Poole, J.; Poulet, M.; Rinaudo, G.; Santroni, A.; Severi, M.; Skjevling, G.; Stapnes, S.; Stugu, B.; R704 Collaboration

1986-04-01

This experiment has been performed at the CERN Intersecting Storage Rings to study the direct formation of charmonium states in antiproton-proton annihilations. The experimental program has partly been devoted to an inclusive scan for overlinepp → J/ψ + X in the range 3520-3530 MeV/ c2. A cluster of five events has been observed in a narrow energy band, centred on the centre of gravity of the 3P J states where the 1P 1 is expected to be. When interpreted as a new resonace, these data yield a mass m = 3525.4±0.8 MeV/ c2.

Ames Hybrid Combustion Facility

NASA Technical Reports Server (NTRS)

Zilliac, Greg; Karabeyoglu, Mustafa A.; Cantwell, Brian; Hunt, Rusty; DeZilwa, Shane; Shoffstall, Mike; Soderman, Paul T.; Bencze, Daniel P. (Technical Monitor)

2003-01-01

The report summarizes the design, fabrication, safety features, environmental impact, and operation of the Ames Hybrid-Fuel Combustion Facility (HCF). The facility is used in conducting research into the scalability and combustion processes of advanced paraffin-based hybrid fuels for the purpose of assessing their applicability to practical rocket systems. The facility was designed to deliver gaseous oxygen at rates between 0.5 and 16.0 kg/sec to a combustion chamber operating at pressures ranging from 300 to 900. The required run times were of the order of 10 to 20 sec. The facility proved to be robust and reliable and has been used to generate a database of regression-rate measurements of paraffin at oxygen mass flux levels comparable to those of moderate-sized hybrid rocket motors.