Handling Qualities of a Large Civil Tiltrotor in Hover using Translational Rate Command

NASA Technical Reports Server (NTRS)

Malpica, Carlos A.; Theodore, Colin R.; Lawrence, Ben; Lindsey, James; Blanken, Chris

2012-01-01

A Translational Rate Command (TRC) control law has been developed to enable low speed maneuvering of a large civil tiltrotor with minimal pitch changes by means of automatic nacelle angle deflections for longitudinal velocity control. The nacelle actuator bandwidth required to achieve Level 1 handling qualities in hover and the feasibility of additional longitudinal cyclic control to augment low bandwidth nacelle actuation were investigated. A frequency-domain handling qualities criterion characterizing TRC response in terms of bandwidth and phase delay was proposed and validated against a piloted simulation conducted on the NASA-Ames Vertical Motion Simulator. Seven experimental test pilots completed evaluations in the ADS-33E-PRF Hover Mission Task Element (MTE) for a matrix of nacelle actuator bandwidths, equivalent rise times and control response sensitivities, and longitudinal cyclic control allocations. Evaluated against this task, longitudinal phase delay shows the Level 1 boundary is around 0.4 0.5 s. Accordingly, Level 1 handling qualities were achieved either with a nacelle actuator bandwidth greater than 4 rad/s, or by employing longitudinal cyclic control to augment low bandwidth nacelle actuation.

The extremely long-tongued neotropical butterfly Eurybia lycisca (Riodinidae): proboscis morphology and flower handling.

PubMed

Bauder, Julia A S; Lieskonig, Nora R; Krenn, Harald W

2011-03-01

Few species of true butterflies (Lepidoptera: Papilionoidea) have evolved a proboscis that greatly exceeds the length of the body. This study is the first to examine the morphology of an extremely long butterfly proboscis and to describe how it is used to obtain nectar from flowers with very deep corolla tubes. The proboscis of Eurybia lycisca (Riodinidae) is approximately twice as long as the body. It has a maximal length of 45.6 mm (mean length 36.5 mm ± 4.1 S.D., N = 20) and is extremely thin, measuring only about 0.26 mm at its maximum diameter. The proboscis has a unique arrangement of short sensilla at the tip, and its musculature arrangement is derived. The flower handling times on the preferred nectar plant, Calathea crotalifera (Marantaceae), were exceptionally long (mean 54.5 sec ± 28.5 S.D., N = 26). When feeding on the deep flowers remarkably few proboscis movements occur. The relationship between Eurybia lycisca and its preferred nectar plant and larval host plant, Calathea crotalifera, is not mutualistic since the butterfly exploits the flowers without contributing to their pollination. We hypothesize that the extraordinarily long proboscis of Eurybia lycisca is an adaptation for capitalizing on the pre-existing mutualistic interaction of the host plant with its pollinating long-tongued nectar feeding insects. Copyright © 2010 Elsevier Ltd. All rights reserved.

The extremely long-tongued Neotropical butterfly Eurybia lycisca (Riodinidae): Proboscis morphology and flower handling

PubMed Central

Bauder, Julia A.S.; Lieskonig, Nora R.; Krenn, Harald W.

2011-01-01

Few species of true butterflies (Lepidoptera: Papilionoidea) have evolved a proboscis that greatly exceeds the length of the body. This study is the first to examine the morphology of an extremely long butterfly proboscis and to describe how it is used to obtain nectar from flowers with very deep corolla tubes. The proboscis of Eurybia lycisca (Riodinidae) is approximately twice as long as the body. It has a maximal length of 45.6 mm (mean length 36.5 mm ± 4.1 S.D., N = 20) and is extremely thin, measuring only about 0.26 mm at its maximum diameter. The proboscis has a unique arrangement of short sensilla at the tip, and its musculature arrangement is derived. The flower handling times on the preferred nectar plant, Calathea crotalifera (Marantaceae), were exceptionally long (mean 54.5 sec ± 28.5 S.D., N = 26). When feeding on the deep flowers remarkably few proboscis movements occur. The relationship between Eurybia lycisca and its preferred nectar plant and larval host plant, Calathea crotalifera, is not mutualistic since the butterfly exploits the flowers without contributing to their pollination. We hypothesize that the extraordinarily long proboscis of Eurybia lycisca is an adaptation for capitalizing on the pre-existing mutualistic interaction of the host plant with its pollinating long-tongued nectar feeding insects. PMID:21115131

Data Mining of Extremely Large Ad Hoc Data Sets to Produce Inverted Indices

DTIC Science & Technology

2016-06-01

NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS Approved for public release; distribution is unlimited DATA MINING OF...COVERED Master’s Thesis 4. TITLE AND SUBTITLE DATA MINING OF EXTREMELY LARGE AD HOC DATA SETS TO PRODUCE INVERTED INDICES 5. FUNDING NUMBERS 6...INTENTIONALLY LEFT BLANK iii Approved for public release; distribution is unlimited DATA MINING OF EXTREMELY LARGE AD HOC DATA SETS TO PRODUCE

Handling Big Data in Medical Imaging: Iterative Reconstruction with Large-Scale Automated Parallel Computation

PubMed Central

Lee, Jae H.; Yao, Yushu; Shrestha, Uttam; Gullberg, Grant T.; Seo, Youngho

2014-01-01

The primary goal of this project is to implement the iterative statistical image reconstruction algorithm, in this case maximum likelihood expectation maximum (MLEM) used for dynamic cardiac single photon emission computed tomography, on Spark/GraphX. This involves porting the algorithm to run on large-scale parallel computing systems. Spark is an easy-to- program software platform that can handle large amounts of data in parallel. GraphX is a graph analytic system running on top of Spark to handle graph and sparse linear algebra operations in parallel. The main advantage of implementing MLEM algorithm in Spark/GraphX is that it allows users to parallelize such computation without any expertise in parallel computing or prior knowledge in computer science. In this paper we demonstrate a successful implementation of MLEM in Spark/GraphX and present the performance gains with the goal to eventually make it useable in clinical setting. PMID:27081299

Safe Patient Handling and Mobility: Development and Implementation of a Large-Scale Education Program.

PubMed

Lee, Corinne; Knight, Suzanne W; Smith, Sharon L; Nagle, Dorothy J; DeVries, Lori

This article addresses the development, implementation, and evaluation of an education program for safe patient handling and mobility at a large academic medical center. The ultimate goal of the program was to increase safety during patient mobility/transfer and reduce nursing staff injury from lifting/pulling. This comprehensive program was designed on the basis of the principles of prework, application, and support at the point of care. A combination of online learning, demonstration, skill evaluation, and coaching at the point of care was used to achieve the goal. Specific roles and responsibilities were developed to facilitate implementation. It took 17 master trainers, 88 certified trainers, 176 unit-based trainers, and 98 coaches to put 3706 nurses and nursing assistants through the program. Evaluations indicated both an increase in knowledge about safe patient handling and an increased ability to safely mobilize patients. The challenge now is sustainability of safe patient-handling practices and the growth and development of trainers and coaches.

Extremely Large Telescope Project Selected in ESFRI Roadmap

NASA Astrophysics Data System (ADS)

2006-10-01

In its first Roadmap, the European Strategy Forum on Research Infrastructures (ESFRI) choose the European Extremely Large Telescope (ELT), for which ESO is presently developing a Reference Design, as one of the large scale projects to be conducted in astronomy, and the only one in optical astronomy. The aim of the ELT project is to build before the end of the next decade an optical/near-infrared telescope with a diameter in the 30-60m range. ESO PR Photo 40/06 The ESFRI Roadmap states: "Extremely Large Telescopes are seen world-wide as one of the highest priorities in ground-based astronomy. They will vastly advance astrophysical knowledge allowing detailed studies of inter alia planets around other stars, the first objects in the Universe, super-massive Black Holes, and the nature and distribution of the Dark Matter and Dark Energy which dominate the Universe. The European Extremely Large Telescope project will maintain and reinforce Europe's position at the forefront of astrophysical research." Said Catherine Cesarsky, Director General of ESO: "In 2004, the ESO Council mandated ESO to play a leading role in the development of an ELT for Europe's astronomers. To that end, ESO has undertaken conceptual studies for ELTs and is currently also leading a consortium of European institutes engaged in studying enabling technologies for such a telescope. The inclusion of the ELT in the ESFRI roadmap, together with the comprehensive preparatory work already done, paves the way for the next phase of this exciting project, the design phase." ESO is currently working, in close collaboration with the European astronomical community and the industry, on a baseline design for an Extremely Large Telescope. The plan is a telescope with a primary mirror between 30 and 60 metres in diameter and a financial envelope of about 750 m Euros. It aims at more than a factor ten improvement in overall performance compared to the current leader in ground based astronomy: the ESO Very Large

Large Scale Meteorological Pattern of Extreme Rainfall in Indonesia

NASA Astrophysics Data System (ADS)

Kuswanto, Heri; Grotjahn, Richard; Rachmi, Arinda; Suhermi, Novri; Oktania, Erma; Wijaya, Yosep

2014-05-01

Extreme Weather Events (EWEs) cause negative impacts socially, economically, and environmentally. Considering these facts, forecasting EWEs is crucial work. Indonesia has been identified as being among the countries most vulnerable to the risk of natural disasters, such as floods, heat waves, and droughts. Current forecasting of extreme events in Indonesia is carried out by interpreting synoptic maps for several fields without taking into account the link between the observed events in the 'target' area with remote conditions. This situation may cause misidentification of the event leading to an inaccurate prediction. Grotjahn and Faure (2008) compute composite maps from extreme events (including heat waves and intense rainfall) to help forecasters identify such events in model output. The composite maps show large scale meteorological patterns (LSMP) that occurred during historical EWEs. Some vital information about the EWEs can be acquired from studying such maps, in addition to providing forecaster guidance. Such maps have robust mid-latitude meteorological patterns (for Sacramento and California Central Valley, USA EWEs). We study the performance of the composite approach for tropical weather condition such as Indonesia. Initially, the composite maps are developed to identify and forecast the extreme weather events in Indramayu district- West Java, the main producer of rice in Indonesia and contributes to about 60% of the national total rice production. Studying extreme weather events happening in Indramayu is important since EWEs there affect national agricultural and fisheries activities. During a recent EWE more than a thousand houses in Indramayu suffered from serious flooding with each home more than one meter underwater. The flood also destroyed a thousand hectares of rice plantings in 5 regencies. Identifying the dates of extreme events is one of the most important steps and has to be carried out carefully. An approach has been applied to identify the

Handling Emergency Management in [an] Object Oriented Modeling Environment

NASA Technical Reports Server (NTRS)

Tokgoz, Berna Eren; Cakir, Volkan; Gheorghe, Adrian V.

2010-01-01

It has been understood that protection of a nation from extreme disasters is a challenging task. Impacts of extreme disasters on a nation's critical infrastructures, economy and society could be devastating. A protection plan itself would not be sufficient when a disaster strikes. Hence, there is a need for a holistic approach to establish more resilient infrastructures to withstand extreme disasters. A resilient infrastructure can be defined as a system or facility that is able to withstand damage, but if affected, can be readily and cost-effectively restored. The key issue to establish resilient infrastructures is to incorporate existing protection plans with comprehensive preparedness actions to respond, recover and restore as quickly as possible, and to minimize extreme disaster impacts. Although national organizations will respond to a disaster, extreme disasters need to be handled mostly by local emergency management departments. Since emergency management departments have to deal with complex systems, they have to have a manageable plan and efficient organizational structures to coordinate all these systems. A strong organizational structure is the key in responding fast before and during disasters, and recovering quickly after disasters. In this study, the entire emergency management is viewed as an enterprise and modelled through enterprise management approach. Managing an enterprise or a large complex system is a very challenging task. It is critical for an enterprise to respond to challenges in a timely manner with quick decision making. This study addresses the problem of handling emergency management at regional level in an object oriented modelling environment developed by use of TopEase software. Emergency Operation Plan of the City of Hampton, Virginia, has been incorporated into TopEase for analysis. The methodology used in this study has been supported by a case study on critical infrastructure resiliency in Hampton Roads.

Ergonomic material-handling device

DOEpatents

Barsnick, Lance E.; Zalk, David M.; Perry, Catherine M.; Biggs, Terry; Tageson, Robert E.

2004-08-24

A hand-held ergonomic material-handling device capable of moving heavy objects, such as large waste containers and other large objects requiring mechanical assistance. The ergonomic material-handling device can be used with neutral postures of the back, shoulders, wrists and knees, thereby reducing potential injury to the user. The device involves two key features: 1) gives the user the ability to adjust the height of the handles of the device to ergonomically fit the needs of the user's back, wrists and shoulders; and 2) has a rounded handlebar shape, as well as the size and configuration of the handles which keep the user's wrists in a neutral posture during manipulation of the device.

An Investigation of Large Tilt-Rotor Short-Term Attitude Response Handling Qualities Requirements in Hover

NASA Technical Reports Server (NTRS)

Malcipa, Carlos; Decker, William A.; Theodore, Colin R.; Blanken, Christopher L.; Berger, Tom

2010-01-01

A piloted simulation investigation was conducted using the NASA Ames Vertical Motion Simulator to study the impact of pitch, roll and yaw attitude bandwidth and phase delay on handling qualities of large tilt-rotor aircraft. Multiple bandwidth and phase delay pairs were investigated for each axis. The simulation also investigated the effect that the pilot offset from the center of gravity has on handling qualities. While pilot offset does not change the dynamics of the vehicle, it does affect the proprioceptive and visual cues and it can have an impact on handling qualities. The experiment concentrated on two primary evaluation tasks: a precision hover task and a simple hover pedal turn. Six pilots flew over 1400 data runs with evaluation comments and objective performance data recorded. The paper will describe the experiment design and methodology, discuss the results of the experiment and summarize the findings.

Identification of large-scale meteorological patterns associated with extreme precipitation in the US northeast

NASA Astrophysics Data System (ADS)

Agel, Laurie; Barlow, Mathew; Feldstein, Steven B.; Gutowski, William J.

2018-03-01

Patterns of daily large-scale circulation associated with Northeast US extreme precipitation are identified using both k-means clustering (KMC) and Self-Organizing Maps (SOM) applied to tropopause height. The tropopause height provides a compact representation of the upper-tropospheric potential vorticity, which is closely related to the overall evolution and intensity of weather systems. Extreme precipitation is defined as the top 1% of daily wet-day observations at 35 Northeast stations, 1979-2008. KMC is applied on extreme precipitation days only, while the SOM algorithm is applied to all days in order to place the extreme results into the overall context of patterns for all days. Six tropopause patterns are identified through KMC for extreme day precipitation: a summertime tropopause ridge, a summertime shallow trough/ridge, a summertime shallow eastern US trough, a deeper wintertime eastern US trough, and two versions of a deep cold-weather trough located across the east-central US. Thirty SOM patterns for all days are identified. Results for all days show that 6 SOM patterns account for almost half of the extreme days, although extreme precipitation occurs in all SOM patterns. The same SOM patterns associated with extreme precipitation also routinely produce non-extreme precipitation; however, on extreme precipitation days the troughs, on average, are deeper and the downstream ridges more pronounced. Analysis of other fields associated with the large-scale patterns show various degrees of anomalously strong moisture transport preceding, and upward motion during, extreme precipitation events.

Approaching the exa-scale: a real-world evaluation of rendering extremely large data sets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Patchett, John M; Ahrens, James P; Lo, Li - Ta

2010-10-15

Extremely large scale analysis is becoming increasingly important as supercomputers and their simulations move from petascale to exascale. The lack of dedicated hardware acceleration for rendering on today's supercomputing platforms motivates our detailed evaluation of the possibility of interactive rendering on the supercomputer. In order to facilitate our understanding of rendering on the supercomputing platform, we focus on scalability of rendering algorithms and architecture envisioned for exascale datasets. To understand tradeoffs for dealing with extremely large datasets, we compare three different rendering algorithms for large polygonal data: software based ray tracing, software based rasterization and hardware accelerated rasterization. We presentmore » a case study of strong and weak scaling of rendering extremely large data on both GPU and CPU based parallel supercomputers using Para View, a parallel visualization tool. Wc use three different data sets: two synthetic and one from a scientific application. At an extreme scale, algorithmic rendering choices make a difference and should be considered while approaching exascale computing, visualization, and analysis. We find software based ray-tracing offers a viable approach for scalable rendering of the projected future massive data sizes.« less

Rare events modeling with support vector machine: Application to forecasting large-amplitude geomagnetic substorms and extreme events in financial markets.

NASA Astrophysics Data System (ADS)

Gavrishchaka, V. V.; Ganguli, S. B.

2001-12-01

Reliable forecasting of rare events in a complex dynamical system is a challenging problem that is important for many practical applications. Due to the nature of rare events, data set available for construction of the statistical and/or machine learning model is often very limited and incomplete. Therefore many widely used approaches including such robust algorithms as neural networks can easily become inadequate for rare events prediction. Moreover in many practical cases models with high-dimensional inputs are required. This limits applications of the existing rare event modeling techniques (e.g., extreme value theory) that focus on univariate cases. These approaches are not easily extended to multivariate cases. Support vector machine (SVM) is a machine learning system that can provide an optimal generalization using very limited and incomplete training data sets and can efficiently handle high-dimensional data. These features may allow to use SVM to model rare events in some applications. We have applied SVM-based system to the problem of large-amplitude substorm prediction and extreme event forecasting in stock and currency exchange markets. Encouraging preliminary results will be presented and other possible applications of the system will be discussed.

Progress on the European Extremely Large Telescope

NASA Astrophysics Data System (ADS)

Spyromilio, Jason; Comerón, Fernando; D'Odorico, Sandro; Kissler-Patig, Markus; Gilmozzi, Roberto

2008-09-01

In December 2006 the ESO Council gave the go-ahead for the European Extremely Large Telescope (E-ELT) three-year Phase B study. The Baseline Reference Design (BRD) was presented to the ESO committees in 2006 and to the community at the Marseille meeting in December 2006. Phase B has been running for one and a half years and a progress report is presented covering science activities, telescope design, instrumentation, site selection and operations. The designs are maturing, in close synergy with industrial contracts, and the proposal for E-ELT construction is expected to be presented to the ESO Council in June 2010.

Extending SME to Handle Large-Scale Cognitive Modeling.

PubMed

Forbus, Kenneth D; Ferguson, Ronald W; Lovett, Andrew; Gentner, Dedre

2017-07-01

Analogy and similarity are central phenomena in human cognition, involved in processes ranging from visual perception to conceptual change. To capture this centrality requires that a model of comparison must be able to integrate with other processes and handle the size and complexity of the representations required by the tasks being modeled. This paper describes extensions to Structure-Mapping Engine (SME) since its inception in 1986 that have increased its scope of operation. We first review the basic SME algorithm, describe psychological evidence for SME as a process model, and summarize its role in simulating similarity-based retrieval and generalization. Then we describe five techniques now incorporated into the SME that have enabled it to tackle large-scale modeling tasks: (a) Greedy merging rapidly constructs one or more best interpretations of a match in polynomial time: O(n 2 log(n)); (b) Incremental operation enables mappings to be extended as new information is retrieved or derived about the base or target, to model situations where information in a task is updated over time; (c) Ubiquitous predicates model the varying degrees to which items may suggest alignment; (d) Structural evaluation of analogical inferences models aspects of plausibility judgments; (e) Match filters enable large-scale task models to communicate constraints to SME to influence the mapping process. We illustrate via examples from published studies how these enable it to capture a broader range of psychological phenomena than before. Copyright © 2016 Cognitive Science Society, Inc.

9 CFR 3.92 - Handling.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Handling. 3.92 Section 3.92 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL...: (1) Shelter from sunlight and extreme heat. Sufficient shade must be provided to protect the nonhuman...

9 CFR 3.92 - Handling.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Handling. 3.92 Section 3.92 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL...: (1) Shelter from sunlight and extreme heat. Sufficient shade must be provided to protect the nonhuman...

9 CFR 3.92 - Handling.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Handling. 3.92 Section 3.92 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL...: (1) Shelter from sunlight and extreme heat. Sufficient shade must be provided to protect the nonhuman...

Pulsed beam of extremely large helium droplets

NASA Astrophysics Data System (ADS)

Kuma, Susumu; Azuma, Toshiyuki

2017-12-01

We generated a pulsed helium droplet beam with average droplet diameters of up to 2 μ m using a solenoid pulsed valve operated at temperatures as low as 7 K. The droplet diameter was controllable over two orders of magnitude, or six orders of the number of atoms per droplet, by lowering the valve temperature from 21 to 7 K. A sudden droplet size change attributed to the so-called ;supercritical expansion; was firstly observed in pulsed mode, which is necessary to obtain the micrometer-scale droplets. This beam source is beneficial for experiments that require extremely large helium droplets in intense, pulsed form.

Uvf - Unified Volume Format: A General System for Efficient Handling of Large Volumetric Datasets.

PubMed

Krüger, Jens; Potter, Kristin; Macleod, Rob S; Johnson, Christopher

2008-01-01

With the continual increase in computing power, volumetric datasets with sizes ranging from only a few megabytes to petascale are generated thousands of times per day. Such data may come from an ordinary source such as simple everyday medical imaging procedures, while larger datasets may be generated from cluster-based scientific simulations or measurements of large scale experiments. In computer science an incredible amount of work worldwide is put into the efficient visualization of these datasets. As researchers in the field of scientific visualization, we often have to face the task of handling very large data from various sources. This data usually comes in many different data formats. In medical imaging, the DICOM standard is well established, however, most research labs use their own data formats to store and process data. To simplify the task of reading the many different formats used with all of the different visualization programs, we present a system for the efficient handling of many types of large scientific datasets (see Figure 1 for just a few examples). While primarily targeted at structured volumetric data, UVF can store just about any type of structured and unstructured data. The system is composed of a file format specification with a reference implementation of a reader. It is not only a common, easy to implement format but also allows for efficient rendering of most datasets without the need to convert the data in memory.

United States Temperature and Precipitation Extremes: Phenomenology, Large-Scale Organization, Physical Mechanisms and Model Representation

NASA Astrophysics Data System (ADS)

Black, R. X.

2017-12-01

We summarize results from a project focusing on regional temperature and precipitation extremes over the continental United States. Our project introduces a new framework for evaluating these extremes emphasizing their (a) large-scale organization, (b) underlying physical sources (including remote-excitation and scale-interaction) and (c) representation in climate models. Results to be reported include the synoptic-dynamic behavior, seasonality and secular variability of cold waves, dry spells and heavy rainfall events in the observational record. We also study how the characteristics of such extremes are systematically related to Northern Hemisphere planetary wave structures and thus planetary- and hemispheric-scale forcing (e.g., those associated with major El Nino events and Arctic sea ice change). The underlying physics of event onset are diagnostically quantified for different categories of events. Finally, the representation of these extremes in historical coupled climate model simulations is studied and the origins of model biases are traced using new metrics designed to assess the large-scale atmospheric forcing of local extremes.

Safe gas handling and system design for the large scale production of amorphous silicon based solar cells

NASA Astrophysics Data System (ADS)

Fortmann, C. M.; Farley, M. V.; Smoot, M. A.; Fieselmann, B. F.

1988-07-01

Solarex is one of the leaders in amorphous silicon based photovoltaic production and research. The large scale production environment presents unique safety concerns related to the quantity of dangerous materials as well as the number of personnel handling these materials. The safety measures explored by this work include gas detection systems, training, and failure resistant gas handling systems. Our experiences with flow restricting orifices in the CGA connections and the use of steel cylinders is reviewed. The hazards and efficiency of wet scrubbers for silane exhausts are examined. We have found it to be useful to provide the scrubbler with temperature alarms.

Evolution of Precipitation Extremes in Three Large Ensembles of Climate Simulations - Impact of Spatial and Temporal Resolutions

NASA Astrophysics Data System (ADS)

Martel, J. L.; Brissette, F.; Mailhot, A.; Wood, R. R.; Ludwig, R.; Frigon, A.; Leduc, M.; Turcotte, R.

2017-12-01

Recent studies indicate that the frequency and intensity of extreme precipitation will increase in future climate due to global warming. In this study, we compare annual maxima precipitation series from three large ensembles of climate simulations at various spatial and temporal resolutions. The first two are at the global scale: the Canadian Earth System Model (CanESM2) 50-member large ensemble (CanESM2-LE) at a 2.8° resolution and the Community Earth System Model (CESM1) 40-member large ensemble (CESM1-LE) at a 1° resolution. The third ensemble is at the regional scale over both Eastern North America and Europe: the Canadian Regional Climate Model (CRCM5) 50-member large ensemble (CRCM5-LE) at a 0.11° resolution, driven at its boundaries by the CanESM-LE. The CRCM5-LE is a new ensemble issued from the ClimEx project (http://www.climex-project.org), a Québec-Bavaria collaboration. Using these three large ensembles, change in extreme precipitations over the historical (1980-2010) and future (2070-2100) periods are investigated. This results in 1 500 (30 years x 50 members for CanESM2-LE and CRCM5-LE) and 1200 (30 years x 40 members for CESM1-LE) simulated years over both the historical and future periods. Using these large datasets, the empirical daily (and sub-daily for CRCM5-LE) extreme precipitation quantiles for large return periods ranging from 2 to 100 years are computed. Results indicate that daily extreme precipitations generally will increase over most land grid points of both domains according to the three large ensembles. Regarding the CRCM5-LE, the increase in sub-daily extreme precipitations will be even more important than the one observed for daily extreme precipitations. Considering that many public infrastructures have lifespans exceeding 75 years, the increase in extremes has important implications on service levels of water infrastructures and public safety.

Mooring and ground handling rigid airships

NASA Technical Reports Server (NTRS)

Walker, H., Jr.

1975-01-01

The problems of mooring and ground handling rigid airships are discussed. A brief history of Mooring and Ground Handling Rigid Airships from July 2, 1900 through September 1, 1939 is included. Also a brief history of ground handling developments with large U. S. Navy nonrigid airships between September 1, 1939 and August 31, 1962 is included wherein developed equipment and techniques appear applicable to future large rigid airships. Finally recommendations are made pertaining to equipment and procedures which appear desirable and feasible for future rigid airship programs.

Alumina Handling Dustiness

NASA Astrophysics Data System (ADS)

Authier-Martin, Monique

Dustiness of calcined alumina is a major concern, causing undesirable working conditions and serious alumina losses. These losses occur primarily during unloading and handling or pot loading and crust breaking. The handling side of the problem is first addressed. The Perra pulvimeter constitutes a simple and reproducible tool to quantify handling dustiness and yields results in agreement with plant experience. Attempts are made to correlate dustiness with bulk properties (particle size, attrition index, …) for a large number of diverse aluminas. The characterization of the dust generated with the Perra pulvimeter is most revealing. The effect of the addition of E.S.P. dust is also reported.

Multicomponent phase-field model for extremely large partition coefficients

DOE Office of Scientific and Technical Information (OSTI.GOV)

Welland, Michael J.; Wolf, Dieter; Guyer, Jonathan E.

2014-01-01

We develop a multicomponent phase-field model specially formulated to robustly simulate concentration variations from molar to atomic magnitudes across an interlace, i.e., partition coefficients in excess of 10±23 such as may be the case with species which are predominant in one phase and insoluble in the other. Substitutional interdiffusion on a normal lattice and concurrent interstitial diffusion are included. The composition in the interlace follows the approach of Kim. Kim, and Suzuki [Phys. Rev. E 60, 7186 (1999)] and is compared to that of Wheeler, Boettinger, and McFadden [Phys. Rev. A 45, 7424 (1992)] in the context of large partitioning.more » The model successfully reproduces analytical solutions for binary diffusion couples and solute trapping for the demonstrated cases of extremely large partitioning.« less

How Do Microphysical Processes Influence Large-Scale Precipitation Variability and Extremes?

DOE PAGES

Hagos, Samson; Ruby Leung, L.; Zhao, Chun; ...

2018-02-10

Convection permitting simulations using the Model for Prediction Across Scales-Atmosphere (MPAS-A) are used to examine how microphysical processes affect large-scale precipitation variability and extremes. An episode of the Madden-Julian Oscillation is simulated using MPAS-A with a refined region at 4-km grid spacing over the Indian Ocean. It is shown that cloud microphysical processes regulate the precipitable water (PW) statistics. Because of the non-linear relationship between precipitation and PW, PW exceeding a certain critical value (PWcr) contributes disproportionately to precipitation variability. However, the frequency of PW exceeding PWcr decreases rapidly with PW, so changes in microphysical processes that shift the columnmore » PW statistics relative to PWcr even slightly have large impacts on precipitation variability. Furthermore, precipitation variance and extreme precipitation frequency are approximately linearly related to the difference between the mean and critical PW values. Thus observed precipitation statistics could be used to directly constrain model microphysical parameters as this study demonstrates using radar observations from DYNAMO field campaign.« less

How Do Microphysical Processes Influence Large-Scale Precipitation Variability and Extremes?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hagos, Samson; Ruby Leung, L.; Zhao, Chun

Convection permitting simulations using the Model for Prediction Across Scales-Atmosphere (MPAS-A) are used to examine how microphysical processes affect large-scale precipitation variability and extremes. An episode of the Madden-Julian Oscillation is simulated using MPAS-A with a refined region at 4-km grid spacing over the Indian Ocean. It is shown that cloud microphysical processes regulate the precipitable water (PW) statistics. Because of the non-linear relationship between precipitation and PW, PW exceeding a certain critical value (PWcr) contributes disproportionately to precipitation variability. However, the frequency of PW exceeding PWcr decreases rapidly with PW, so changes in microphysical processes that shift the columnmore » PW statistics relative to PWcr even slightly have large impacts on precipitation variability. Furthermore, precipitation variance and extreme precipitation frequency are approximately linearly related to the difference between the mean and critical PW values. Thus observed precipitation statistics could be used to directly constrain model microphysical parameters as this study demonstrates using radar observations from DYNAMO field campaign.« less

Dynamical analysis of extreme precipitation in the US northeast based on large-scale meteorological patterns

NASA Astrophysics Data System (ADS)

Agel, Laurie; Barlow, Mathew; Colby, Frank; Binder, Hanin; Catto, Jennifer L.; Hoell, Andrew; Cohen, Judah

2018-05-01

Previous work has identified six large-scale meteorological patterns (LSMPs) of dynamic tropopause height associated with extreme precipitation over the Northeast US, with extreme precipitation defined as the top 1% of daily station precipitation. Here, we examine the three-dimensional structure of the tropopause LSMPs in terms of circulation and factors relevant to precipitation, including moisture, stability, and synoptic mechanisms associated with lifting. Within each pattern, the link between the different factors and extreme precipitation is further investigated by comparing the relative strength of the factors between days with and without the occurrence of extreme precipitation. The six tropopause LSMPs include two ridge patterns, two eastern US troughs, and two troughs centered over the Ohio Valley, with a strong seasonality associated with each pattern. Extreme precipitation in the ridge patterns is associated with both convective mechanisms (instability combined with moisture transport from the Great Lakes and Western Atlantic) and synoptic forcing related to Great Lakes storm tracks and embedded shortwaves. Extreme precipitation associated with eastern US troughs involves intense southerly moisture transport and strong quasi-geostrophic forcing of vertical velocity. Ohio Valley troughs are associated with warm fronts and intense warm conveyor belts that deliver large amounts of moisture ahead of storms, but little direct quasi-geostrophic forcing. Factors that show the largest difference between days with and without extreme precipitation include integrated moisture transport, low-level moisture convergence, warm conveyor belts, and quasi-geostrophic forcing, with the relative importance varying between patterns.

Handling qualities of large flexible control-configured aircraft

NASA Technical Reports Server (NTRS)

Swaim, R. L.

1979-01-01

The approach to an analytical study of flexible airplane longitudinal handling qualities was to parametrically vary the natural frequencies of two symmetric elastic modes to induce mode interactions with the rigid body dynamics. Since the structure of the pilot model was unknown for such dynamic interactions, the optimal control pilot modeling method is being applied and used in conjunction with pilot rating method.

The Management Challenge: Handling Exams Involving Large Quantities of Students, on and off Campus--A Design Concept

ERIC Educational Resources Information Center

Larsson, Ken

2014-01-01

This paper looks at the process of managing large numbers of exams efficiently and secure with the use of a dedicated IT support. The system integrates regulations on different levels, from national to local, (even down to departments) and ensures that the rules are employed in all stages of handling the exams. The system has a proven record of…

Durham extremely large telescope adaptive optics simulation platform.

PubMed

Basden, Alastair; Butterley, Timothy; Myers, Richard; Wilson, Richard

2007-03-01

Adaptive optics systems are essential on all large telescopes for which image quality is important. These are complex systems with many design parameters requiring optimization before good performance can be achieved. The simulation of adaptive optics systems is therefore necessary to categorize the expected performance. We describe an adaptive optics simulation platform, developed at Durham University, which can be used to simulate adaptive optics systems on the largest proposed future extremely large telescopes as well as on current systems. This platform is modular, object oriented, and has the benefit of hardware application acceleration that can be used to improve the simulation performance, essential for ensuring that the run time of a given simulation is acceptable. The simulation platform described here can be highly parallelized using parallelization techniques suited for adaptive optics simulation, while still offering the user complete control while the simulation is running. The results from the simulation of a ground layer adaptive optics system are provided as an example to demonstrate the flexibility of this simulation platform.

Instrument control software requirement specification for Extremely Large Telescopes

NASA Astrophysics Data System (ADS)

Young, Peter J.; Kiekebusch, Mario J.; Chiozzi, Gianluca

2010-07-01

Engineers in several observatories are now designing the next generation of optical telescopes, the Extremely Large Telescopes (ELT). These are very complex machines that will host sophisticated astronomical instruments to be used for a wide range of scientific studies. In order to carry out scientific observations, a software infrastructure is required to orchestrate the control of the multiple subsystems and functions. This paper will focus on describing the considerations, strategies and main issues related to the definition and analysis of the software requirements for the ELT's Instrument Control System using modern development processes and modelling tools like SysML.

Finger doses for staff handling radiopharmaceuticals in nuclear medicine.

PubMed

Pant, Gauri S; Sharma, Sanjay K; Rath, Gaura K

2006-09-01

Radiation doses to the fingers of occupational workers handling 99mTc-labeled compounds and 131I for diagnostic and therapeutic procedures in nuclear medicine were measured by thermoluminescence dosimetry. The doses were measured at the base of the ring finger and the index finger of both hands in 2 groups of workers. Group 1 (7 workers) handled 99mTc-labeled radiopharmaceuticals, and group 2 (6 workers) handled 131I for diagnosis and therapy. Radiation doses to the fingertips of 3 workers also were measured. Two were from group 1, and 1 was from group 2. The doses to the base of the fingers for the radiopharmacy staff and physicians from group 1 were observed to be 17+/-7.5 (mean+/-SD) and 13.4+/-6.5 microSv/GBq, respectively. Similarly, the dose to the base of the fingers for the 3 physicians in group 2 was estimated to be 82.0+/-13.8 microSv/GBq. Finger doses for the technologists in both groups could not be calculated per unit of activity because they did not handle the radiopharmaceuticals directly. Their doses were reported in millisieverts that accumulated in 1 wk. The doses to the fingertips of the radiopharmacy worker and the physician in group 1 were 74.3+/-19.8 and 53.5+/-21.9 microSv/GBq, respectively. The dose to the fingertips of the physician in group 2 was 469.9+/-267 microSv/GBq. The radiation doses to the fingers of nuclear medicine staff at our center were measured. The maximum expected annual dose to the extremities appeared to be less than the annual limit (500 mSv/y), except for a physician who handled large quantities of 131I for treatment. Because all of these workers are on rotation and do not constantly handle radioactivity throughout the year, the doses to the base of the fingers or the fingertips should not exceed the prescribed annual limit of 500 mSv.

Mynodbcsv: lightweight zero-config database solution for handling very large CSV files.

PubMed

Adaszewski, Stanisław

2014-01-01

Volumes of data used in science and industry are growing rapidly. When researchers face the challenge of analyzing them, their format is often the first obstacle. Lack of standardized ways of exploring different data layouts requires an effort each time to solve the problem from scratch. Possibility to access data in a rich, uniform manner, e.g. using Structured Query Language (SQL) would offer expressiveness and user-friendliness. Comma-separated values (CSV) are one of the most common data storage formats. Despite its simplicity, with growing file size handling it becomes non-trivial. Importing CSVs into existing databases is time-consuming and troublesome, or even impossible if its horizontal dimension reaches thousands of columns. Most databases are optimized for handling large number of rows rather than columns, therefore, performance for datasets with non-typical layouts is often unacceptable. Other challenges include schema creation, updates and repeated data imports. To address the above-mentioned problems, I present a system for accessing very large CSV-based datasets by means of SQL. It's characterized by: "no copy" approach--data stay mostly in the CSV files; "zero configuration"--no need to specify database schema; written in C++, with boost [1], SQLite [2] and Qt [3], doesn't require installation and has very small size; query rewriting, dynamic creation of indices for appropriate columns and static data retrieval directly from CSV files ensure efficient plan execution; effortless support for millions of columns; due to per-value typing, using mixed text/numbers data is easy; very simple network protocol provides efficient interface for MATLAB and reduces implementation time for other languages. The software is available as freeware along with educational videos on its website [4]. It doesn't need any prerequisites to run, as all of the libraries are included in the distribution package. I test it against existing database solutions using a battery of

Mynodbcsv: Lightweight Zero-Config Database Solution for Handling Very Large CSV Files

PubMed Central

Adaszewski, Stanisław

2014-01-01

Volumes of data used in science and industry are growing rapidly. When researchers face the challenge of analyzing them, their format is often the first obstacle. Lack of standardized ways of exploring different data layouts requires an effort each time to solve the problem from scratch. Possibility to access data in a rich, uniform manner, e.g. using Structured Query Language (SQL) would offer expressiveness and user-friendliness. Comma-separated values (CSV) are one of the most common data storage formats. Despite its simplicity, with growing file size handling it becomes non-trivial. Importing CSVs into existing databases is time-consuming and troublesome, or even impossible if its horizontal dimension reaches thousands of columns. Most databases are optimized for handling large number of rows rather than columns, therefore, performance for datasets with non-typical layouts is often unacceptable. Other challenges include schema creation, updates and repeated data imports. To address the above-mentioned problems, I present a system for accessing very large CSV-based datasets by means of SQL. It's characterized by: “no copy” approach – data stay mostly in the CSV files; “zero configuration” – no need to specify database schema; written in C++, with boost [1], SQLite [2] and Qt [3], doesn't require installation and has very small size; query rewriting, dynamic creation of indices for appropriate columns and static data retrieval directly from CSV files ensure efficient plan execution; effortless support for millions of columns; due to per-value typing, using mixed text/numbers data is easy; very simple network protocol provides efficient interface for MATLAB and reduces implementation time for other languages. The software is available as freeware along with educational videos on its website [4]. It doesn't need any prerequisites to run, as all of the libraries are included in the distribution package. I test it against existing database solutions using

Large-Scale Atmospheric Circulation Patterns Associated with Temperature Extremes as a Basis for Model Evaluation: Methodological Overview and Results

NASA Astrophysics Data System (ADS)

Loikith, P. C.; Broccoli, A. J.; Waliser, D. E.; Lintner, B. R.; Neelin, J. D.

2015-12-01

Anomalous large-scale circulation patterns often play a key role in the occurrence of temperature extremes. For example, large-scale circulation can drive horizontal temperature advection or influence local processes that lead to extreme temperatures, such as by inhibiting moderating sea breezes, promoting downslope adiabatic warming, and affecting the development of cloud cover. Additionally, large-scale circulation can influence the shape of temperature distribution tails, with important implications for the magnitude of future changes in extremes. As a result of the prominent role these patterns play in the occurrence and character of extremes, the way in which temperature extremes change in the future will be highly influenced by if and how these patterns change. It is therefore critical to identify and understand the key patterns associated with extremes at local to regional scales in the current climate and to use this foundation as a target for climate model validation. This presentation provides an overview of recent and ongoing work aimed at developing and applying novel approaches to identifying and describing the large-scale circulation patterns associated with temperature extremes in observations and using this foundation to evaluate state-of-the-art global and regional climate models. Emphasis is given to anomalies in sea level pressure and 500 hPa geopotential height over North America using several methods to identify circulation patterns, including self-organizing maps and composite analysis. Overall, evaluation results suggest that models are able to reproduce observed patterns associated with temperature extremes with reasonable fidelity in many cases. Model skill is often highest when and where synoptic-scale processes are the dominant mechanisms for extremes, and lower where sub-grid scale processes (such as those related to topography) are important. Where model skill in reproducing these patterns is high, it can be inferred that extremes are

HAND TRUCK FOR HANDLING EQUIPMENT

DOEpatents

King, D.W.

1959-02-24

A truck is described for the handling of large and relatively heavy pieces of equipment and particularly for the handling of ion source units for use in calutrons. The truck includes a chassis and a frame pivoted to the chassis so as to be operable to swing in the manner of a boom. The frame has spaced members so arranged that the device to be handled can be suspended between or passed between these spaced members and also rotated with respect to the frame when the device is secured to the spaced members.

Extreme temperatures and out-of-hospital coronary deaths in six large Chinese cities.

PubMed

Chen, Renjie; Li, Tiantian; Cai, Jing; Yan, Meilin; Zhao, Zhuohui; Kan, Haidong

2014-12-01

The seasonal trend of out-of-hospital coronary death (OHCD) and sudden cardiac death has been observed, but whether extreme temperature serves as a risk factor is rarely investigated. We therefore aimed to evaluate the impact of extreme temperatures on OHCDs in China. We obtained death records of 126,925 OHCDs from six large Chinese cities (Harbin, Beijing, Tianjin, Nanjing, Shanghai and Guangzhou) during the period 2009-2011. The short-term associations between extreme temperature and OHCDs were analysed with time-series methods in each city, using generalised additive Poisson regression models. We specified distributed lag non-linear models in studying the delayed effects of extreme temperature. We then applied Bayesian hierarchical models to combine the city-specific effect estimates. The associations between extreme temperature and OHCDs were almost U-shaped or J-shaped. The pooled relative risks (RRs) of extreme cold temperatures over the lags 0-14 days comparing the 1st and 25th centile temperatures were 1.49 (95% posterior interval (PI) 1.26-1.76); the pooled RRs of extreme hot temperatures comparing the 99th and 75th centile temperatures were 1.53 (95% PI 1.27-1.84) for OHCDs. The RRs of extreme temperature on OHCD were higher if the patients with coronary heart disease were old, male and less educated. This multicity epidemiological study suggested that both extreme cold and hot temperatures posed significant risks on OHCDs, and might have important public health implications for the prevention of OHCD or sudden cardiac death. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Extremely large breast abscess in a breastfeeding mother.

PubMed

Martic, Krešimir; Vasilj, Oliver

2012-11-01

Puerperal mastitis often occurs in younger primiparous women. Most cases occur between 3 and 8 weeks postpartum. If mastitis results in the formation of a breast abscess, surgical drainage or needle aspiration is most commonly performed. We report a case of an extremely large breast abscess in a primiparous 20-year-old woman, which presented 6 weeks postpartum. Surgical incision and evacuation of 2 liters of exudate were performed, and intravenous antibiotics therapy was administered. On the sixth day after incision, we secondarily closed the wound. Examination after 3 months showed symmetrical breasts with a small scar in the incision area of the right breast. A high degree of suspicion and adequate diagnostic procedures are essential to avoid delay in the treatment of mastitis and breast abscess and thereby prevent unnecessary surgical treatment.

Large scale meteorological patterns and moisture sources during precipitation extremes over South Asia

NASA Astrophysics Data System (ADS)

Mehmood, S.; Ashfaq, M.; Evans, K. J.; Black, R. X.; Hsu, H. H.

2017-12-01

Extreme precipitation during summer season has shown an increasing trend across South Asia in recent decades, causing an exponential increase in weather related losses. Here we combine a cluster analyses technique (Agglomerative Hierarchical Clustering) with a Lagrangian based moisture analyses technique to investigate potential commonalities in the characteristics of the large scale meteorological patterns (LSMP) and moisture anomalies associated with the observed extreme precipitation events, and their representation in the Department of Energy model ACME. Using precipitation observations from the Indian Meteorological Department (IMD) and Asian Precipitation Highly Resolved Observational Data Integration Towards Evaluation (APHRODITE), and atmospheric variables from Era-Interim Reanalysis, we first identify LSMP both in upper and lower troposphere that are responsible for wide spread precipitation extreme events during 1980-2015 period. For each of the selected extreme event, we perform moisture source analyses to identify major evaporative sources that sustain anomalous moisture supply during the course of the event, with a particular focus on local terrestrial moisture recycling. Further, we perform similar analyses on two sets of five-member ensemble of ACME model (1-degree and ¼ degree) to investigate the ability of ACME model in simulating precipitation extremes associated with each of the LSMP patterns and associated anomalous moisture sourcing from each of the terrestrial and oceanic evaporative region. Comparison of low and high-resolution model configurations provides insight about the influence of horizontal grid spacing in the simulation of extreme precipitation and the governing mechanisms.

Status and path to a final EUVL reticle-handling solution

NASA Astrophysics Data System (ADS)

He, Long; Orvek, Kevin; Seidel, Phil; Wurm, Stefan; Underwood, Jon; Betancourt, Ernie

2007-03-01

In extreme ultraviolet lithography (EUVL), the lack of a suitable material to build conventional pellicles calls for industry standardization of new techniques for protection and handling throughout the reticle's lifetime. This includes reticle shipping, robotic handling, in-fab transport, storage, and uses in atmospheric environments for metrology and vacuum environments for EUV exposure. In this paper, we review the status of the industry-wide progress in developing EUVL reticle-handling solutions. We show the industry's leading reticle carrier approaches for particle-free protection, such as improvements in conventional single carrier designs and new EUVL-specific carrier concepts, including variations on a removable pellicle. Our test indicates dual pod approach of the removable pellicle led to nearly particle-free use during a simulated life cycle, at ~50nm inspection sensitivity. We will provide an assessment of the remaining technical challenges facing EUVL reticle-handling technology. Finally, we will review the progress of the SEMI EUVL Reticle-handling Task Force in its efforts to standardize a final EUV reticle protection and handling solution.

A Bit-Encoding Based New Data Structure for Time and Memory Efficient Handling of Spike Times in an Electrophysiological Setup.

PubMed

Ljungquist, Bengt; Petersson, Per; Johansson, Anders J; Schouenborg, Jens; Garwicz, Martin

2018-04-01

Recent neuroscientific and technical developments of brain machine interfaces have put increasing demands on neuroinformatic databases and data handling software, especially when managing data in real time from large numbers of neurons. Extrapolating these developments we here set out to construct a scalable software architecture that would enable near-future massive parallel recording, organization and analysis of neurophysiological data on a standard computer. To this end we combined, for the first time in the present context, bit-encoding of spike data with a specific communication format for real time transfer and storage of neuronal data, synchronized by a common time base across all unit sources. We demonstrate that our architecture can simultaneously handle data from more than one million neurons and provide, in real time (< 25 ms), feedback based on analysis of previously recorded data. In addition to managing recordings from very large numbers of neurons in real time, it also has the capacity to handle the extensive periods of recording time necessary in certain scientific and clinical applications. Furthermore, the bit-encoding proposed has the additional advantage of allowing an extremely fast analysis of spatiotemporal spike patterns in a large number of neurons. Thus, we conclude that this architecture is well suited to support current and near-future Brain Machine Interface requirements.

The problem of extreme events in paired-watershed studies

Treesearch

James W. Hornbeck

1973-01-01

In paired-watershed studies, the occurrence of an extreme event during the after-treatment period presents a problem: the effects of treatment must be determined by using greatly extrapolated regression statistics. Several steps are presented to help insure careful handling of extreme events during analysis and reporting of research results.

Ergonomics of disposable handles for minimally invasive surgery.

PubMed

Büchel, D; Mårvik, R; Hallabrin, B; Matern, U

2010-05-01

The ergonomic deficiencies of currently available minimally invasive surgery (MIS) instrument handles have been addressed in many studies. In this study, a new ergonomic pistol handle concept, realized as a prototype, and two disposable ring handles were investigated according to ergonomic properties set by new European standards. In this study, 25 volunteers performed four practical tasks to evaluate the ergonomics of the handles used in standard operating procedures (e.g., measuring a suture and cutting to length, precise maneuvering and targeting, and dissection of a gallbladder). Moreover, 20 participants underwent electromyography (EMG) tests to measure the muscle strain they experienced while carrying out the basic functions (grasp, rotate, and maneuver) in the x, y, and z axes. The data measured included the number of errors, the time required for task completion, perception of pressure areas, and EMG data. The values for usability in the test were effectiveness, efficiency, and user satisfaction. Surveys relating to the subjective rating were completed after each task for each of the three handles tested. Each handle except the new prototype caused pressure areas and pain. Extreme differences in muscle strain could not be observed for any of the three handles. Experienced surgeons worked more quickly with the prototype when measuring and cutting a suture (approximately 20%) and during precise maneuvering and targeting (approximately 20%). On the other hand, they completed the dissection task faster with the handle manufactured by Ethicon. Fewer errors were made with the prototype in dissection of the gallbladder. In contrast to the handles available on the market, the prototype was always rated as positive by the volunteers in the subjective surveys. None of the handles could fulfil all of the requirements with top scores. Each handle had its advantages and disadvantages. In contrast to the ring handles, the volunteers could fulfil most of the tasks more

[Parallel virtual reality visualization of extreme large medical datasets].

PubMed

Tang, Min

2010-04-01

On the basis of a brief description of grid computing, the essence and critical techniques of parallel visualization of extreme large medical datasets are discussed in connection with Intranet and common-configuration computers of hospitals. In this paper are introduced several kernel techniques, including the hardware structure, software framework, load balance and virtual reality visualization. The Maximum Intensity Projection algorithm is realized in parallel using common PC cluster. In virtual reality world, three-dimensional models can be rotated, zoomed, translated and cut interactively and conveniently through the control panel built on virtual reality modeling language (VRML). Experimental results demonstrate that this method provides promising and real-time results for playing the role in of a good assistant in making clinical diagnosis.

Electric-field-induced extremely large change in resistance in graphene ferromagnets

NASA Astrophysics Data System (ADS)

Song, Yu

2018-01-01

A colossal magnetoresistance (˜100×10^3% ) and an extremely large magnetoresistance (˜1×10^6% ) have been previously explored in manganite perovskites and Dirac materials, respectively. However, the requirement of an extremely strong magnetic field (and an extremely low temperature) makes them not applicable for realistic devices. In this work, we propose a device that can generate even larger changes in resistance in a zero-magnetic field and at a high temperature. The device is composed of graphene under two strips of yttrium iron garnet (YIG), where two gate voltages are applied to cancel the heavy charge doping in the YIG-induced half-metallic ferromagnets. By calculations using the Landauer-Büttiker formalism, we demonstrate that, when a proper gate voltage is applied on the free ferromagnet, changes in resistance up to 305×10^6% (16×10^3% ) can be achieved at the liquid helium (nitrogen) temperature and in a zero magnetic field. We attribute such a remarkable effect to a gate-induced full-polarization reversal in the free ferromagnet, which results in a metal-state to insulator-state transition in the device. We also find that the proposed effect can be realized in devices using other magnetic insulators, such as EuO and EuS. Our work should be helpful for developing a realistic switching device that is energy saving and CMOS-technology compatible.

Exploration of the aftermath of a large collision in an extreme debris disk

NASA Astrophysics Data System (ADS)

Moor, Attila; Abraham, Peter; Cataldi, Gianni; Kospal, Agnes; Pal, Andras; Vida, Krisztian

2018-05-01

Warm debris disks with extremely high fractional luminosities are exceptional, rare systems. Not explainable by steady-state evolutionary models, these extreme debris disks are believed to stem from a recent large collision of planetary embryos in the terrestrial zone. Our team recently discovered a new extreme debris disk around TYC 4209-1322-1, whose WISE W1/W2 band photometry showed a significant brightening probably related to a giant collision in the inner disk. In Cycle 13 we monitor the system by Spitzer, revealing a fading trend with an e-folding time of 1500 days with hints for a quasi-periodic modulation and a possible second smaller amplitude collision event. Here we propose to continue the monitoring campaign until the end of Cycle 14 to explore the evolution of the current long fading trend and of the second collision, and characterize the hinted modulation. Thanks to a better sampled Spitzer light curve and the unique opportunity that NASA's TESS satellite will obtain high-precision optical photometry in the same period, a new dimension will be opened in Cycle 14 in the study of one of the most spectacular extreme debris disk, scrutinizing for the first time the possible influence of stellar activity on a debris disk.

Generating extreme weather event sets from very large ensembles of regional climate models

NASA Astrophysics Data System (ADS)

Massey, Neil; Guillod, Benoit; Otto, Friederike; Allen, Myles; Jones, Richard; Hall, Jim

2015-04-01

Generating extreme weather event sets from very large ensembles of regional climate models Neil Massey, Benoit P. Guillod, Friederike E. L. Otto, Myles R. Allen, Richard Jones, Jim W. Hall Environmental Change Institute, University of Oxford, Oxford, UK Extreme events can have large impacts on societies and are therefore being increasingly studied. In particular, climate change is expected to impact the frequency and intensity of these events. However, a major limitation when investigating extreme weather events is that, by definition, only few events are present in observations. A way to overcome this issue it to use large ensembles of model simulations. Using the volunteer distributed computing (VDC) infrastructure of weather@home [1], we run a very large number (10'000s) of RCM simulations over the European domain at a resolution of 25km, with an improved land-surface scheme, nested within a free-running GCM. Using VDC allows many thousands of climate model runs to be computed. Using observations for the GCM boundary forcings we can run historical "hindcast" simulations over the past 100 to 150 years. This allows us, due to the chaotic variability of the atmosphere, to ascertain how likely an extreme event was, given the boundary forcings, and to derive synthetic event sets. The events in these sets did not actually occur in the observed record but could have occurred given the boundary forcings, with an associated probability. The event sets contain time-series of fields of meteorological variables that allow impact modellers to assess the loss the event would incur. Projections of events into the future are achieved by modelling projections of the sea-surface temperature (SST) and sea-ice boundary forcings, by combining the variability of the SST in the observed record with a range of warming signals derived from the varying responses of SSTs in the CMIP5 ensemble to elevated greenhouse gas (GHG) emissions in three RCP scenarios. Simulating the future with a

The spatiotemporal changes in precipitation extremes over Canada and their connections to large-scale climate patterns

NASA Astrophysics Data System (ADS)

Yang, Y.; Gan, T. Y.; Tan, X.

2017-12-01

In the past few decades, there have been more extreme climate events around the world, and Canada has also suffered from numerous extreme precipitation events. In this paper, trend analysis, change point analysis, probability distribution function, principal component analysis and wavelet analysis were used to investigate the spatial and temporal patterns of extreme precipitation in Canada. Ten extreme precipitation indices were calculated using long-term daily precipitation data from 164 gauging stations. Several large-scale climate patterns such as El Niño-Southern Oscillation (ENSO), Pacific Decadal Oscillation (PDO), Pacific-North American (PNA), and North Atlantic Oscillation (NAO) were selected to analyze the relationships between extreme precipitation and climate indices. Convective Available Potential Energy (CAPE), specific humidity, and surface temperature were employed to investigate the potential causes of the trends.The results show statistically significant positive trends for most indices, which indicate increasing extreme precipitation. The majority of indices display more increasing trends along the southern border of Canada while decreasing trends dominate in the central Canadian Prairies (CP). In addition, strong connections are found between the extreme precipitation and climate indices and the effects of climate pattern differ for each region. The seasonal CAPE, specific humidity, and temperature are found to be closely related to Canadian extreme precipitation.

Contribution of large-scale circulation anomalies to changes in extreme precipitation frequency in the United States

NASA Astrophysics Data System (ADS)

Yu, Lejiang; Zhong, Shiyuan; Pei, Lisi; Bian, Xindi; Heilman, Warren E.

2016-04-01

The mean global climate has warmed as a result of the increasing emission of greenhouse gases induced by human activities. This warming is considered the main reason for the increasing number of extreme precipitation events in the US. While much attention has been given to extreme precipitation events occurring over several days, which are usually responsible for severe flooding over a large region, little is known about how extreme precipitation events that cause flash flooding and occur at sub-daily time scales have changed over time. Here we use the observed hourly precipitation from the North American Land Data Assimilation System Phase 2 forcing datasets to determine trends in the frequency of extreme precipitation events of short (1 h, 3 h, 6 h, 12 h and 24 h) duration for the period 1979-2013. The results indicate an increasing trend in the central and eastern US. Over most of the western US, especially the Southwest and the Intermountain West, the trends are generally negative. These trends can be largely explained by the interdecadal variability of the Pacific Decadal Oscillation and Atlantic Multidecadal Oscillation (AMO), with the AMO making a greater contribution to the trends in both warm and cold seasons.

Coupled large-eddy simulation and morphodynamics of a large-scale river under extreme flood conditions

NASA Astrophysics Data System (ADS)

Khosronejad, Ali; Sotiropoulos, Fotis; Stony Brook University Team

2016-11-01

We present a coupled flow and morphodynamic simulations of extreme flooding in 3 km long and 300 m wide reach of the Mississippi River in Minnesota, which includes three islands and hydraulic structures. We employ the large-eddy simulation (LES) and bed-morphodynamic modules of the VFS-Geophysics model to investigate the flow and bed evolution of the river during a 500 year flood. The coupling of the two modules is carried out via a fluid-structure interaction approach using a nested domain approach to enhance the resolution of bridge scour predictions. The geometrical data of the river, islands and structures are obtained from LiDAR, sub-aqueous sonar and in-situ surveying to construct a digital map of the river bathymetry. Our simulation results for the bed evolution of the river reveal complex sediment dynamics near the hydraulic structures. The numerically captured scour depth near some of the structures reach a maximum of about 10 m. The data-driven simulation strategy we present in this work exemplifies a practical simulation-based-engineering-approach to investigate the resilience of infrastructures to extreme flood events in intricate field-scale riverine systems. This work was funded by a Grant from Minnesota Dept. of Transportation.

Development of longitudinal handling qualities criteria for large advanced supersonic aircraft

NASA Technical Reports Server (NTRS)

Sudderth, R. W.; Bohn, J. G.; Caniff, M. A.; Bennett, G. R.

1975-01-01

Longitudinal handling qualities criteria in terms of airplane response characteristics were developed. The criteria cover high speed cruise maneuvering, landing approach, and stall recovery. Data substantiating the study results are reported.

Applied extreme-value statistics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kinnison, R.R.

1983-05-01

The statistical theory of extreme values is a well established part of theoretical statistics. Unfortunately, it is seldom part of applied statistics and is infrequently a part of statistical curricula except in advanced studies programs. This has resulted in the impression that it is difficult to understand and not of practical value. In recent environmental and pollution literature, several short articles have appeared with the purpose of documenting all that is necessary for the practical application of extreme value theory to field problems (for example, Roberts, 1979). These articles are so concise that only a statistician can recognise all themore » subtleties and assumptions necessary for the correct use of the material presented. The intent of this text is to expand upon several recent articles, and to provide the necessary statistical background so that the non-statistician scientist can recognize and extreme value problem when it occurs in his work, be confident in handling simple extreme value problems himself, and know when the problem is statistically beyond his capabilities and requires consultation.« less

Wind and wave extremes over the world oceans from very large ensembles

NASA Astrophysics Data System (ADS)

Breivik, Øyvind; Aarnes, Ole Johan; Abdalla, Saleh; Bidlot, Jean-Raymond; Janssen, Peter A. E. M.

2014-07-01

Global return values of marine wind speed and significant wave height are estimated from very large aggregates of archived ensemble forecasts at +240 h lead time. Long lead time ensures that the forecasts represent independent draws from the model climate. Compared with ERA-Interim, a reanalysis, the ensemble yields higher return estimates for both wind speed and significant wave height. Confidence intervals are much tighter due to the large size of the data set. The period (9 years) is short enough to be considered stationary even with climate change. Furthermore, the ensemble is large enough for nonparametric 100 year return estimates to be made from order statistics. These direct return estimates compare well with extreme value estimates outside areas with tropical cyclones. Like any method employing modeled fields, it is sensitive to tail biases in the numerical model, but we find that the biases are moderate outside areas with tropical cyclones.

The National Extreme Events Data and Research Center (NEED)

NASA Astrophysics Data System (ADS)

Gulledge, J.; Kaiser, D. P.; Wilbanks, T. J.; Boden, T.; Devarakonda, R.

2014-12-01

The Climate Change Science Institute at Oak Ridge National Laboratory (ORNL) is establishing the National Extreme Events Data and Research Center (NEED), with the goal of transforming how the United States studies and prepares for extreme weather events in the context of a changing climate. NEED will encourage the myriad, distributed extreme events research communities to move toward the adoption of common practices and will develop a new database compiling global historical data on weather- and climate-related extreme events (e.g., heat waves, droughts, hurricanes, etc.) and related information about impacts, costs, recovery, and available research. Currently, extreme event information is not easy to access and is largely incompatible and inconsistent across web sites. NEED's database development will take into account differences in time frames, spatial scales, treatments of uncertainty, and other parameters and variables, and leverage informatics tools developed at ORNL (i.e., the Metadata Editor [1] and Mercury [2]) to generate standardized, robust documentation for each database along with a web-searchable catalog. In addition, NEED will facilitate convergence on commonly accepted definitions and standards for extreme events data and will enable integrated analyses of coupled threats, such as hurricanes/sea-level rise/flooding and droughts/wildfires. Our goal and vision is that NEED will become the premiere integrated resource for the general study of extreme events. References: [1] Devarakonda, Ranjeet, et al. "OME: Tool for generating and managing metadata to handle BigData." Big Data (Big Data), 2014 IEEE International Conference on. IEEE, 2014. [2] Devarakonda, Ranjeet, et al. "Mercury: reusable metadata management, data discovery and access system." Earth Science Informatics 3.1-2 (2010): 87-94.

An extremely bright gamma-ray pulsar in the Large Magellanic Cloud

NASA Astrophysics Data System (ADS)

Fermi LAT Collaboration; Ackermann, M.; Albert, A.; Baldini, L.; Ballet, J.; Barbiellini, G.; Barbieri, C.; Bastieri, D.; Bellazzini, R.; Bissaldi, E.; Bonino, R.; Bottacini, E.; Brandt, T. J.; Bregeon, J.; Bruel, P.; Buehler, R.; Caliandro, G. A.; Cameron, R. A.; Caraveo, P. A.; Cecchi, C.; Charles, E.; Chekhtman, A.; Cheung, C. C.; Chiang, J.; Chiaro, G.; Ciprini, S.; Cohen-Tanugi, J.; Cuoco, A.; Cutini, S.; D'Ammando, F.; Desiante, F. de Palma R.; Digel, S. W.; Di Venere, L.; Drell, P. S.; Favuzzi, C.; Fegan, S. J.; Ferrara, E. C.; Franckowiak, A.; Funk, S.; Fusco, P.; Gargano, F.; Gasparrini, D.; Giglietto, N.; Giordano, F.; Godfrey, G.; Grenier, I. A.; Grondin, M.-H.; Grove, J. E.; Guillemot, L.; Guiriec, S.; Hagiwara, K.; Harding, A. K.; Hays, E.; Hewitt, J. W.; Hill, A. B.; Horan, D.; Johnson, T. J.; Knödlseder, J.; Kuss, M.; Larsson, S.; Latronico, L.; Lemoine-Goumard, M.; Li, J.; Li, L.; Longo, F.; Loparco, F.; Lovellette, M. N.; Lubrano, P.; Maldera, S.; Manfreda, A.; Marshall, F.; Martin, P.; Mayer, M.; Mazziotta, M. N.; Michelson, P. F.; Mirabal, N.; Mizuno, T.; Monzani, M. E.; Morselli, A.; Moskalenko, I. V.; Murgia, S.; Naletto, G.; Nuss, E.; Ohsugi, T.; Orienti, M.; Orlando, E.; Paneque, D.; Pesce-Rollins, M.; Piron, F.; Pivato, G.; Porter, T. A.; Rainò, S.; Rando, R.; Razzano, M.; Reimer, A.; Reimer, O.; Reposeur, T.; Romani, R. W.; Parkinson, P. M. Saz; Schulz, A.; Sgrò, C.; Siskind, E. J.; Smith, D. A.; Spada, F.; Spandre, G.; Spinelli, P.; Suson, D. J.; Takahashi, H.; Thayer, J. B.; Thompson, D. J.; Tibaldo, L.; Torres, D. F.; Uchiyama, Y.; Vianello, G.; Wood, K. S.; Wood, M.; Zampieri, L.

2015-11-01

Pulsars are rapidly spinning, highly magnetized neutron stars, created in the gravitational collapse of massive stars. We report the detection of pulsed giga-electron volt gamma rays from the young pulsar PSR J0540-6919 in the Large Magellanic Cloud, a satellite galaxy of the Milky Way. This is the first gamma-ray pulsar detected in another galaxy. It has the most luminous pulsed gamma-ray emission yet observed, exceeding the Crab pulsar’s by a factor of 20. PSR J0540-6919 presents an extreme test case for understanding the structure and evolution of neutron star magnetospheres.

Physically-based extreme flood frequency with stochastic storm transposition and paleoflood data on large watersheds

NASA Astrophysics Data System (ADS)

England, John F.; Julien, Pierre Y.; Velleux, Mark L.

2014-03-01

Traditionally, deterministic flood procedures such as the Probable Maximum Flood have been used for critical infrastructure design. Some Federal agencies now use hydrologic risk analysis to assess potential impacts of extreme events on existing structures such as large dams. Extreme flood hazard estimates and distributions are needed for these efforts, with very low annual exceedance probabilities (⩽10-4) (return periods >10,000 years). An integrated data-modeling hydrologic hazard framework for physically-based extreme flood hazard estimation is presented. Key elements include: (1) a physically-based runoff model (TREX) coupled with a stochastic storm transposition technique; (2) hydrometeorological information from radar and an extreme storm catalog; and (3) streamflow and paleoflood data for independently testing and refining runoff model predictions at internal locations. This new approach requires full integration of collaborative work in hydrometeorology, flood hydrology and paleoflood hydrology. An application on the 12,000 km2 Arkansas River watershed in Colorado demonstrates that the size and location of extreme storms are critical factors in the analysis of basin-average rainfall frequency and flood peak distributions. Runoff model results are substantially improved by the availability and use of paleoflood nonexceedance data spanning the past 1000 years at critical watershed locations.

North American Extreme Temperature Events and Related Large Scale Meteorological Patterns: A Review of Statistical Methods, Dynamics, Modeling, and Trends

NASA Technical Reports Server (NTRS)

Grotjahn, Richard; Black, Robert; Leung, Ruby; Wehner, Michael F.; Barlow, Mathew; Bosilovich, Michael G.; Gershunov, Alexander; Gutowski, William J., Jr.; Gyakum, John R.; Katz, Richard W.;

A Large-Scale Multi-Hop Localization Algorithm Based on Regularized Extreme Learning for Wireless Networks.

PubMed

Zheng, Wei; Yan, Xiaoyong; Zhao, Wei; Qian, Chengshan

2017-12-20

A novel large-scale multi-hop localization algorithm based on regularized extreme learning is proposed in this paper. The large-scale multi-hop localization problem is formulated as a learning problem. Unlike other similar localization algorithms, the proposed algorithm overcomes the shortcoming of the traditional algorithms which are only applicable to an isotropic network, therefore has a strong adaptability to the complex deployment environment. The proposed algorithm is composed of three stages: data acquisition, modeling and location estimation. In data acquisition stage, the training information between nodes of the given network is collected. In modeling stage, the model among the hop-counts and the physical distances between nodes is constructed using regularized extreme learning. In location estimation stage, each node finds its specific location in a distributed manner. Theoretical analysis and several experiments show that the proposed algorithm can adapt to the different topological environments with low computational cost. Furthermore, high accuracy can be achieved by this method without setting complex parameters.

Dynamic stability and handling qualities tests on a highly augmented, statically unstable airplane

NASA Technical Reports Server (NTRS)

Gera, Joseph; Bosworth, John T.

1987-01-01

Initial envelope clearance and subsequent flight testing of a new, fully augmented airplane with an extremely high degree of static instability can place unusual demands on the flight test approach. Previous flight test experience with these kinds of airplanes is very limited or nonexistent. The safe and efficient flight testing may be further complicated by a multiplicity of control effectors that may be present on this class of airplanes. This paper describes some novel flight test and analysis techniques in the flight dynamics and handling qualities area. These techniques were utilized during the initial flight envelope clearance of the X-29A aircraft and were largely responsible for the completion of the flight controls clearance program without any incidents or significant delays.

The extreme ultraviolet explorer archive

NASA Astrophysics Data System (ADS)

Polomski, E.; Drake, J. J.; Dobson, C.; Christian, C.

1993-09-01

The Extreme Ultrviolet Explorer (EUVE) public archive was created to handle the storage, maintenance, and distribution of EUVE data and ancillary documentation, information, and software. Access to the archive became available to the public on July 17, 1992, only 40 days after the launch of the EUVE satellite. A brief overview of the archive's contents and the various methods of access will be described.

Extremely large magnetoresistance in a high-quality WTe2 grown by flux method

NASA Astrophysics Data System (ADS)

Tsumura, K.; Yano, R.; Kashiwaya, H.; Koyanagi, M.; Masubuchi, S.; Machida, T.; Namiki, H.; Sasagawa, T.; Kashiwaya, S.

2018-03-01

We have grown single crystals of WTe2 by a self-flux method and evaluated the quality of the crystals. A Hall bar-type device was fabricated from an as-exfoliated film on a Si substrate and longitudinal resistance Rxx was measured. Rxx increased with an applied perpendicular magnetic field without saturation and an extremely large magnetoresistance as high as 376,059 % was observed at 8.27 T and 1.7 K.

An analytical study of electric vehicle handling dynamics

NASA Technical Reports Server (NTRS)

Greene, J. E.; Segal, D. J.

1979-01-01

Hypothetical electric vehicle configurations were studied by applying available analytical methods. Elementary linearized models were used in addition to a highly sophisticated vehicle dynamics computer simulation technique. Physical properties of specific EV's were defined for various battery and powertrain packaging approaches applied to a range of weight distribution and inertial properties which characterize a generic class of EV's. Computer simulations of structured maneuvers were performed for predicting handling qualities in the normal driving range and during various extreme conditions related to accident avoidance. Results indicate that an EV with forward weight bias will possess handling qualities superior to a comparable EV that is rear-heavy or equally balanced. The importance of properly matching tires, suspension systems, and brake system front/rear torque proportioning to a given EV configuration during the design stage is demonstrated.

An extremely bright gamma-ray pulsar in the Large Magellanic Cloud.

PubMed

2015-11-13

Pulsars are rapidly spinning, highly magnetized neutron stars, created in the gravitational collapse of massive stars. We report the detection of pulsed giga-electron volt gamma rays from the young pulsar PSR J0540-6919 in the Large Magellanic Cloud, a satellite galaxy of the Milky Way. This is the first gamma-ray pulsar detected in another galaxy. It has the most luminous pulsed gamma-ray emission yet observed, exceeding the Crab pulsar's by a factor of 20. PSR J0540-6919 presents an extreme test case for understanding the structure and evolution of neutron star magnetospheres. Copyright © 2015, American Association for the Advancement of Science.

Care and handling of container plants from storage to outplanting

Treesearch

Thomas D. Landis; R. Kasten Dumroese

2011-01-01

Nursery plants are in a period of high risk from the time they leave the protected environment of the nursery to when they are outplanted. During handling and shipping, nursery stock may be exposed to many damaging stresses, including extreme temperatures, desiccation, mechanical injuries, and storage molds. This is also the period of greatest financial risk, because...

Simulating observations with HARMONI: the integral field spectrograph for the European Extremely Large Telescope

NASA Astrophysics Data System (ADS)

Zieleniewski, Simon; Thatte, Niranjan; Kendrew, Sarah; Houghton, Ryan; Tecza, Matthias; Clarke, Fraser; Fusco, Thierry; Swinbank, Mark

2014-07-01

With the next generation of extremely large telescopes commencing construction, there is an urgent need for detailed quantitative predictions of the scientific observations that these new telescopes will enable. Most of these new telescopes will have adaptive optics fully integrated with the telescope itself, allowing unprecedented spatial resolution combined with enormous sensitivity. However, the adaptive optics point spread function will be strongly wavelength dependent, requiring detailed simulations that accurately model these variations. We have developed a simulation pipeline for the HARMONI integral field spectrograph, a first light instrument for the European Extremely Large Telescope. The simulator takes high-resolution input data-cubes of astrophysical objects and processes them with accurate atmospheric, telescope and instrumental effects, to produce mock observed cubes for chosen observing parameters. The output cubes represent the result of a perfect data reduc- tion process, enabling a detailed analysis and comparison between input and output, showcasing HARMONI's capabilities. The simulations utilise a detailed knowledge of the telescope's wavelength dependent adaptive op- tics point spread function. We discuss the simulation pipeline and present an early example of the pipeline functionality for simulating observations of high redshift galaxies.

Spatial extreme value analysis to project extremes of large-scale indicators for severe weather

PubMed Central

Gilleland, Eric; Brown, Barbara G; Ammann, Caspar M

2013-01-01

Concurrently high values of the maximum potential wind speed of updrafts (Wmax) and 0–6 km wind shear (Shear) have been found to represent conducive environments for severe weather, which subsequently provides a way to study severe weather in future climates. Here, we employ a model for the product of these variables (WmSh) from the National Center for Atmospheric Research/United States National Center for Environmental Prediction reanalysis over North America conditioned on their having extreme energy in the spatial field in order to project the predominant spatial patterns of WmSh. The approach is based on the Heffernan and Tawn conditional extreme value model. Results suggest that this technique estimates the spatial behavior of WmSh well, which allows for exploring possible changes in the patterns over time. While the model enables a method for inferring the uncertainty in the patterns, such analysis is difficult with the currently available inference approach. A variation of the method is also explored to investigate how this type of model might be used to qualitatively understand how the spatial patterns of WmSh correspond to extreme river flow events. A case study for river flows from three rivers in northwestern Tennessee is studied, and it is found that advection of WmSh from the Gulf of Mexico prevails while elsewhere, WmSh is generally very low during such extreme events. © 2013 The Authors. Environmetrics published by JohnWiley & Sons, Ltd. PMID:24223482

North American extreme temperature events and related large scale meteorological patterns: A review of statistical methods, dynamics, modeling, and trends

DOE PAGES

Grotjahn, Richard; Black, Robert; Leung, Ruby; ...

2015-05-22

This paper reviews research approaches and open questions regarding data, statistical analyses, dynamics, modeling efforts, and trends in relation to temperature extremes. Our specific focus is upon extreme events of short duration (roughly less than 5 days) that affect parts of North America. These events are associated with large scale meteorological patterns (LSMPs). Methods used to define extreme events statistics and to identify and connect LSMPs to extreme temperatures are presented. Recent advances in statistical techniques can connect LSMPs to extreme temperatures through appropriately defined covariates that supplements more straightforward analyses. A wide array of LSMPs, ranging from synoptic tomore » planetary scale phenomena, have been implicated as contributors to extreme temperature events. Current knowledge about the physical nature of these contributions and the dynamical mechanisms leading to the implicated LSMPs is incomplete. There is a pressing need for (a) systematic study of the physics of LSMPs life cycles and (b) comprehensive model assessment of LSMP-extreme temperature event linkages and LSMP behavior. Generally, climate models capture the observed heat waves and cold air outbreaks with some fidelity. However they overestimate warm wave frequency and underestimate cold air outbreaks frequency, and underestimate the collective influence of low-frequency modes on temperature extremes. Climate models have been used to investigate past changes and project future trends in extreme temperatures. Overall, modeling studies have identified important mechanisms such as the effects of large-scale circulation anomalies and land-atmosphere interactions on changes in extreme temperatures. However, few studies have examined changes in LSMPs more specifically to understand the role of LSMPs on past and future extreme temperature changes. Even though LSMPs are resolvable by global and regional climate models, they are not necessarily well simulated so

A Search for H(alpha) Emission in the Far Outer Discs of Extremely Large Spiral Galaxies

NASA Astrophysics Data System (ADS)

Rubin, Vera; Hunter, Deidre

2007-08-01

Little is known about the kinematics of galaxies far beyond the relatively bright regions sampled in radio or optical radial velocity studies. Most often, the velocities are obtained as part of large surveys, where the effort is made to obtain many rotation curves, rather than to extend a rotation curve as far as possible. Because the composition of dark matter remains unknown, it is important to devise observations that will help to constrain its properties. We propose to obtain ultra-deep Hα images (in the rest frame of the galaxy) for UGC 2885 and NGC 801, two extremely large Sc galaxies. We expect to detect Hα regions far beyond their nuclei and into the extreme outer disc, for which we will then obtain radial velocities. Increased knowledge concerning the kinematics of these galaxies will tighten the constraints on mass models, and shed light on the properties of dark matter. Ultimately, we hope to learn more about the outermost galaxy, where disc and halo blend.

Laser guide star wavefront sensing for ground-layer adaptive optics on extremely large telescopes.

PubMed

Clare, Richard M; Le Louarn, Miska; Béchet, Clementine

2011-02-01

We propose ground-layer adaptive optics (GLAO) to improve the seeing on the 42 m European Extremely Large Telescope. Shack-Hartmann wavefront sensors (WFSs) with laser guide stars (LGSs) will experience significant spot elongation due to off-axis observation. This spot elongation influences the design of the laser launch location, laser power, WFS detector, and centroiding algorithm for LGS GLAO on an extremely large telescope. We show, using end-to-end numerical simulations, that with a noise-weighted matrix-vector-multiply reconstructor, the performance in terms of 50% ensquared energy (EE) of the side and central launch of the lasers is equivalent, the matched filter and weighted center of gravity centroiding algorithms are the most promising, and approximately 10×10 undersampled pixels are optimal. Significant improvement in the 50% EE can be observed with a few tens of photons/subaperture/frame, and no significant gain is seen by adding more than 200 photons/subaperture/frame. The LGS GLAO is not particularly sensitive to the sodium profile present in the mesosphere nor to a short-timescale (less than 100 s) evolution of the sodium profile. The performance of LGS GLAO is, however, sensitive to the atmospheric turbulence profile.

Extreme weather events in southern Germany - Climatological risk and development of a large-scale identification procedure

NASA Astrophysics Data System (ADS)

Matthies, A.; Leckebusch, G. C.; Rohlfing, G.; Ulbrich, U.

2009-04-01

Extreme weather events such as thunderstorms, hail and heavy rain or snowfall can pose a threat to human life and to considerable tangible assets. Yet there is a lack of knowledge about present day climatological risk and its economic effects, and its changes due to rising greenhouse gas concentrations. Therefore, parts of economy particularly sensitve to extreme weather events such as insurance companies and airports require regional risk-analyses, early warning and prediction systems to cope with such events. Such an attempt is made for southern Germany, in close cooperation with stakeholders. Comparing ERA40 and station data with impact records of Munich Re and Munich Airport, the 90th percentile was found to be a suitable threshold for extreme impact relevant precipitation events. Different methods for the classification of causing synoptic situations have been tested on ERA40 reanalyses. An objective scheme for the classification of Lamb's circulation weather types (CWT's) has proved to be most suitable for correct classification of the large-scale flow conditions. Certain CWT's have been turned out to be prone to heavy precipitation or on the other side to have a very low risk of such events. Other large-scale parameters are tested in connection with CWT's to find out a combination that has the highest skill to identify extreme precipitation events in climate model data (ECHAM5 and CLM). For example vorticity advection in 700 hPa shows good results, but assumes knowledge of regional orographic particularities. Therefore ongoing work is focused on additional testing of parameters that indicate deviations of a basic state of the atmosphere like the Eady Growth Rate or the newly developed Dynamic State Index. Evaluation results will be used to estimate the skill of the regional climate model CLM concerning the simulation of frequency and intensity of the extreme weather events. Data of the A1B scenario (2000-2050) will be examined for a possible climate change

A large, benign prostatic cyst presented with an extremely high serum prostate-specific antigen level.

PubMed

Chen, Han-Kuang; Pemberton, Richard

2016-01-08

We report a case of a patient who presented with an extremely high serum prostate specific antigen (PSA) level and underwent radical prostatectomy for presumed prostate cancer. Surprisingly, the whole mount prostatectomy specimen showed only small volume, organ-confined prostate adenocarcinoma and a large, benign intraprostatic cyst, which was thought to be responsible for the PSA elevation. 2016 BMJ Publishing Group Ltd.

A Look at Technologies Vis-a-vis Information Handling Techniques.

ERIC Educational Resources Information Center

Swanson, Rowena W.

The paper examines several ideas for information handling implemented with new technologies that suggest directions for future development. These are grouped under the topic headings: Handling Large Data Banks, Providing Personalized Information Packages, Providing Information Specialist Services, and Expanding Man-Machine Interaction. Guides in…

Extremely large magnetoresistance and high-density Dirac-like fermions in ZrB2

NASA Astrophysics Data System (ADS)

Wang, Qi; Guo, Peng-Jie; Sun, Shanshan; Li, Chenghe; Liu, Kai; Lu, Zhong-Yi; Lei, Hechang

2018-05-01

We report the detailed study on transport properties of ZrB2 single crystal, a predicted topological nodal-line semimetal. ZrB2 exhibits extremely large magnetoresistance as well as field-induced resistivity upturn and plateau. These behaviors can be well understood by the two-band model with the perfect electron-hole compensation and high carrier mobilities. More importantly, the electrons with small effective masses and nontrivial Berry phase have significantly high density when compared to those in known topological semimetals. It strongly suggests that ZrB2 hosts Dirac-like nodal-line fermions.

Construction of a ratiometric fluorescent probe with an extremely large emission shift for imaging hypochlorite in living cells

NASA Astrophysics Data System (ADS)

Song, Xuezhen; Dong, Baoli; Kong, Xiuqi; Wang, Chao; Zhang, Nan; Lin, Weiying

2018-01-01

Hypochlorite is one of the important reactive oxygen species (ROS) and plays critical roles in many biologically vital processes. Herein, we present a unique ratiometric fluorescent probe (CBP) with an extremely large emission shift for detecting hypochlorite in living cells. Utilizing positively charged α,β-unsaturated carbonyl group as the reaction site, the probe CBP itself exhibited near-infrared (NIR) fluorescence at 662 nm, and can display strong blue fluorescence at 456 nm when responded to hypochlorite. Notably, the extremely large emission shift of 206 nm could enable the precise measurement of the fluorescence peak intensities and ratios. CBP showed high sensitivity, excellent selectivity, desirable performance at physiological pH, and low cytotoxicity. The bioimaging experiments demonstrate the biological application of CBP for the ratiometric imaging of hypochlorite in living cells.

Contribution of large-scale midlatitude disturbances to hourly precipitation extremes in the United States

NASA Astrophysics Data System (ADS)

Barbero, Renaud; Abatzoglou, John T.; Fowler, Hayley J.

2018-02-01

Midlatitude synoptic weather regimes account for a substantial portion of annual precipitation accumulation as well as multi-day precipitation extremes across parts of the United States (US). However, little attention has been devoted to understanding how synoptic-scale patterns contribute to hourly precipitation extremes. A majority of 1-h annual maximum precipitation (AMP) across the western US were found to be linked to two coherent midlatitude synoptic patterns: disturbances propagating along the jet stream, and cutoff upper-level lows. The influence of these two patterns on 1-h AMP varies geographically. Over 95% of 1-h AMP along the western coastal US were coincident with progressive midlatitude waves embedded within the jet stream, while over 30% of 1-h AMP across the interior western US were coincident with cutoff lows. Between 30-60% of 1-h AMP were coincident with the jet stream across the Ohio River Valley and southeastern US, whereas a a majority of 1-h AMP over the rest of central and eastern US were not found to be associated with either midlatitude synoptic features. Composite analyses for 1-h AMP days coincident to cutoff lows and jet stream show that an anomalous moisture flux and upper-level dynamics are responsible for initiating instability and setting up an environment conducive to 1-h AMP events. While hourly precipitation extremes are generally thought to be purely convective in nature, this study shows that large-scale dynamics and baroclinic disturbances may also contribute to precipitation extremes on sub-daily timescales.

Super Clausius-Clapeyron scaling of extreme hourly precipitation and its relation to large-scale atmospheric conditions

NASA Astrophysics Data System (ADS)

Lenderink, Geert; Barbero, Renaud; Loriaux, Jessica; Fowler, Hayley

2017-04-01

Present-day precipitation-temperature scaling relations indicate that hourly precipitation extremes may have a response to warming exceeding the Clausius-Clapeyron (CC) relation; for The Netherlands the dependency on surface dew point temperature follows two times the CC relation corresponding to 14 % per degree. Our hypothesis - as supported by a simple physical argument presented here - is that this 2CC behaviour arises from the physics of convective clouds. So, we think that this response is due to local feedbacks related to the convective activity, while other large scale atmospheric forcing conditions remain similar except for the higher temperature (approximately uniform warming with height) and absolute humidity (corresponding to the assumption of unchanged relative humidity). To test this hypothesis, we analysed the large-scale atmospheric conditions accompanying summertime afternoon precipitation events using surface observations combined with a regional re-analysis for the data in The Netherlands. Events are precipitation measurements clustered in time and space derived from approximately 30 automatic weather stations. The hourly peak intensities of these events again reveal a 2CC scaling with the surface dew point temperature. The temperature excess of moist updrafts initialized at the surface and the maximum cloud depth are clear functions of surface dew point temperature, confirming the key role of surface humidity on convective activity. Almost no differences in relative humidity and the dry temperature lapse rate were found across the dew point temperature range, supporting our theory that 2CC scaling is mainly due to the response of convection to increases in near surface humidity, while other atmospheric conditions remain similar. Additionally, hourly precipitation extremes are on average accompanied by substantial large-scale upward motions and therefore large-scale moisture convergence, which appears to accelerate with surface dew point. This

Vertical interferometer workstation for testing large spherical optics

NASA Astrophysics Data System (ADS)

Truax, B.

2013-09-01

The design of an interferometer workstation for the testing of large concave and convex spherical optics is presented. The workstation handles optical components and mounts up to 425 mm in diameter with mass of up to 40 kg with 6 axes of adjustment. A unique method for the implementation of focus, roll and pitch was used allowing for extremely precise adjustment. The completed system includes transmission spheres with f-numbers from f/1.6 to f/0.82 incorporating reference surface diameters of up to 306 mm and surface accuracies of better than 63 nm PVr. The design challenges and resulting solutions are discussed. System performance results are presented.

Reducing Mouse Anxiety during Handling: Effect of Experience with Handling Tunnels

PubMed Central

Gouveia, Kelly; Hurst, Jane L.

2013-01-01

Handling stress is a well-recognised source of variation in animal studies that can also compromise the welfare of research animals. To reduce background variation and maximise welfare, methods that minimise handling stress should be developed and used wherever possible. Recent evidence has shown that handling mice by a familiar tunnel that is present in their home cage can minimise anxiety compared with standard tail handling. As yet, it is unclear whether a tunnel is required in each home cage to improve response to handling. We investigated the influence of prior experience with home tunnels among two common strains of laboratory mice: ICR(CD-1) and C57BL/6. We compared willingness to approach the handler and anxiety in an elevated plus maze test among mice picked up by the tail, by a home cage tunnel or by an external tunnel shared between cages. Willingness to interact with the handler was much greater for mice handled by a tunnel, even when this was unfamiliar, compared to mice picked up by the tail. Once habituated to handling, C57BL/6 mice were most interactive towards a familiar home tunnel, whereas the ICR strain showed strong interaction with all tunnel handling regardless of any experience of a home cage tunnel. Mice handled by a home cage or external tunnel showed less anxiety in an elevated plus maze than those picked up by the tail. This study shows that using a tunnel for routine handling reduces anxiety among mice compared to tail handling regardless of prior familiarity with tunnels. However, as home cage tunnels can further improve response to handling in some mice, we recommend that mice are handled with a tunnel provided in their home cage where possible as a simple practical method to minimise handling stress. PMID:23840458

Reducing mouse anxiety during handling: effect of experience with handling tunnels.

PubMed

Gouveia, Kelly; Hurst, Jane L

2013-01-01

Handling stress is a well-recognised source of variation in animal studies that can also compromise the welfare of research animals. To reduce background variation and maximise welfare, methods that minimise handling stress should be developed and used wherever possible. Recent evidence has shown that handling mice by a familiar tunnel that is present in their home cage can minimise anxiety compared with standard tail handling. As yet, it is unclear whether a tunnel is required in each home cage to improve response to handling. We investigated the influence of prior experience with home tunnels among two common strains of laboratory mice: ICR(CD-1) and C57BL/6. We compared willingness to approach the handler and anxiety in an elevated plus maze test among mice picked up by the tail, by a home cage tunnel or by an external tunnel shared between cages. Willingness to interact with the handler was much greater for mice handled by a tunnel, even when this was unfamiliar, compared to mice picked up by the tail. Once habituated to handling, C57BL/6 mice were most interactive towards a familiar home tunnel, whereas the ICR strain showed strong interaction with all tunnel handling regardless of any experience of a home cage tunnel. Mice handled by a home cage or external tunnel showed less anxiety in an elevated plus maze than those picked up by the tail. This study shows that using a tunnel for routine handling reduces anxiety among mice compared to tail handling regardless of prior familiarity with tunnels. However, as home cage tunnels can further improve response to handling in some mice, we recommend that mice are handled with a tunnel provided in their home cage where possible as a simple practical method to minimise handling stress.

Extreme Mean and Its Applications

NASA Technical Reports Server (NTRS)

Swaroop, R.; Brownlow, J. D.

1979-01-01

Extreme value statistics obtained from normally distributed data are considered. An extreme mean is defined as the mean of p-th probability truncated normal distribution. An unbiased estimate of this extreme mean and its large sample distribution are derived. The distribution of this estimate even for very large samples is found to be nonnormal. Further, as the sample size increases, the variance of the unbiased estimate converges to the Cramer-Rao lower bound. The computer program used to obtain the density and distribution functions of the standardized unbiased estimate, and the confidence intervals of the extreme mean for any data are included for ready application. An example is included to demonstrate the usefulness of extreme mean application.

Neutron Star Astronomy in the era of the European Extremely Large Telescope

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mignani, Roberto P.

About 25 isolated neutron stars (INSs) are now detected in the optical domain, mainly thanks to the HST and to VLT-class telescopes. The European Extremely Large Telescope(E-ELT) will yield {approx}100 new identifications, many of which from the follow-up of SKA, IXO, and Fermi observations. Moreover, the E-ELT will allow to carry out, on a much larger sample, INS observations which still challenge VLT-class telescopes, enabling studies on the structure and composition of the NS interior, of its atmosphere and magnetosphere, as well as to search for debris discs. In this contribution, I outline future perspectives for NS optical astronomy withmore » the E-ELT.« less

Computational data sciences for assessment and prediction of climate extremes

NASA Astrophysics Data System (ADS)

Ganguly, A. R.

2011-12-01

Climate extremes may be defined inclusively as severe weather events or large shifts in global or regional weather patterns which may be caused or exacerbated by natural climate variability or climate change. This area of research arguably represents one of the largest knowledge-gaps in climate science which is relevant for informing resource managers and policy makers. While physics-based climate models are essential in view of non-stationary and nonlinear dynamical processes, their current pace of uncertainty reduction may not be adequate for urgent stakeholder needs. The structure of the models may in some cases preclude reduction of uncertainty for critical processes at scales or for the extremes of interest. On the other hand, methods based on complex networks, extreme value statistics, machine learning, and space-time data mining, have demonstrated significant promise to improve scientific understanding and generate enhanced predictions. When combined with conceptual process understanding at multiple spatiotemporal scales and designed to handle massive data, interdisciplinary data science methods and algorithms may complement or supplement physics-based models. Specific examples from the prior literature and our ongoing work suggests how data-guided improvements may be possible, for example, in the context of ocean meteorology, climate oscillators, teleconnections, and atmospheric process understanding, which in turn can improve projections of regional climate, precipitation extremes and tropical cyclones in an useful and interpretable fashion. A community-wide effort is motivated to develop and adapt computational data science tools for translating climate model simulations to information relevant for adaptation and policy, as well as for improving our scientific understanding of climate extremes from both observed and model-simulated data.

Sprag Handle Wrenches

NASA Technical Reports Server (NTRS)

Vranishm, John M.

2010-01-01

Sprag handle wrenches have been proposed for general applications in which conventional pawl-and-ratchet wrenches and sprag and cam "clickless" wrenches are now used. Sprag handle wrenches are so named because they would include components that would function both as parts of handles and as sprags (roller locking/unlocking components). In comparison with all of the aforementioned conventional wrenches, properly designed sprag handle wrenches could operate with much less backlash; in comparison with the conventional clickless wrenches, sprag handle wrenches could be stronger and less expensive (because the sprags would be larger and more easily controllable than are conventional sprags and cams).

Capturing spatial and temporal patterns of widespread, extreme flooding across Europe

NASA Astrophysics Data System (ADS)

Busby, Kathryn; Raven, Emma; Liu, Ye

2013-04-01

Statistical characterisation of physical hazards is an integral part of probabilistic catastrophe models used by the reinsurance industry to estimate losses from large scale events. Extreme flood events are not restricted by country boundaries which poses an issue for reinsurance companies as their exposures often extend beyond them. We discuss challenges and solutions that allow us to appropriately capture the spatial and temporal dependence of extreme hydrological events on a continental-scale, which in turn enables us to generate an industry-standard stochastic event set for estimating financial losses for widespread flooding. By presenting our event set methodology, we focus on explaining how extreme value theory (EVT) and dependence modelling are used to account for short, inconsistent hydrological data from different countries, and how to make appropriate statistical decisions that best characterise the nature of flooding across Europe. The consistency of input data is of vital importance when identifying historical flood patterns. Collating data from numerous sources inherently causes inconsistencies and we demonstrate our robust approach to assessing the data and refining it to compile a single consistent dataset. This dataset is then extrapolated using a parameterised EVT distribution to estimate extremes. Our method then captures the dependence of flood events across countries using an advanced multivariate extreme value model. Throughout, important statistical decisions are explored including: (1) distribution choice; (2) the threshold to apply for extracting extreme data points; (3) a regional analysis; (4) the definition of a flood event, which is often linked with reinsurance industry's hour's clause; and (5) handling of missing values. Finally, having modelled the historical patterns of flooding across Europe, we sample from this model to generate our stochastic event set comprising of thousands of events over thousands of years. We then briefly

Transportation and handling loads

NASA Technical Reports Server (NTRS)

Ostrem, F. E.

1971-01-01

Criteria and recommended practices are presented for the prediction and verification of transportation and handling loads for the space vehicle structure and for monitoring these loads during transportation and handling of the vehicle or major vehicle segments. Elements of the transportation and handling systems, and the forcing functions and associated loads are described. The forcing functions for common carriers and typical handling devices are assessed, and emphasis is given to the assessment of loads at the points where the space vehicle is supported during transportation and handling. Factors which must be considered when predicting the loads include the transportation and handling medium; type of handling fixture; transport vehicle speed; types of terrain; weather (changes in pressure of temperature, wind, etc.); and dynamics of the transportation modes or handling devices (acceleration, deceleration, and rotations of the transporter or handling device).

Observing Planetary Nebulae with JWST and Extremely Large Telescopes

NASA Astrophysics Data System (ADS)

Sahai, Raghvendra

2015-01-01

Most stars in the Universe that leave the main sequence in a Hubble time will end their lives evolving through the Planetary Nebula (PN) evolutionary phase. The heavy mass loss which occurs during the preceding AGB phase is important across astrophysics, dramatically changing the course of stellar evolution, dominantly contributing to the dust content of the interstellar medium, and influencing its chemical composition. The evolution from the AGB phase to the PN phases remains poorly understood, especially the dramatic transformation that occurs in the morphology of the mass-ejecta as AGB stars and their round circumstellar envelopes evolve into mostly PNe, the majority of which deviate strongly from spherical symmetry. In addition, although the PN [OIII] luminosity function (PNLF) has been used as a standard candle (on par with distance indicators such as Cepheids), we do not understand why it works. It has been argued that the resolution of these issues may be linked to binarity and associated processes such as mass transfer and common envelope evolution.Thus, understanding the formation and evolution of PNe is of wide astrophysical importance. PNe have long been known to emit across a very large span of wavelengths, from the radio to X-rays. Extensive use of space-based observatories at X-ray (Chandra/ XMM-Newton), optical (HST) and far-infrared (Spitzer, Herschel) wavelengths in recent years has produced significant new advances in our knowledge of these objects. Given the expected advent of the James Webb Space Telescope in the near future, and ground-based Extremely Large Telescope(s) somewhat later, this talk will focus on future high-angular-resolution, high-sensitivity observations at near and mid-IR wavelengths with these facilities that can help in addressing the major unsolved problems in the study of PNe.

Evaluation of large-scale meteorological patterns associated with temperature extremes in the NARCCAP regional climate model simulations

NASA Astrophysics Data System (ADS)

Loikith, Paul C.; Waliser, Duane E.; Lee, Huikyo; Neelin, J. David; Lintner, Benjamin R.; McGinnis, Seth; Mearns, Linda O.; Kim, Jinwon

2015-12-01

Large-scale meteorological patterns (LSMPs) associated with temperature extremes are evaluated in a suite of regional climate model (RCM) simulations contributing to the North American Regional Climate Change Assessment Program. LSMPs are characterized through composites of surface air temperature, sea level pressure, and 500 hPa geopotential height anomalies concurrent with extreme temperature days. Six of the seventeen RCM simulations are driven by boundary conditions from reanalysis while the other eleven are driven by one of four global climate models (GCMs). Four illustrative case studies are analyzed in detail. Model fidelity in LSMP spatial representation is high for cold winter extremes near Chicago. Winter warm extremes are captured by most RCMs in northern California, with some notable exceptions. Model fidelity is lower for cool summer days near Houston and extreme summer heat events in the Ohio Valley. Physical interpretation of these patterns and identification of well-simulated cases, such as for Chicago, boosts confidence in the ability of these models to simulate days in the tails of the temperature distribution. Results appear consistent with the expectation that the ability of an RCM to reproduce a realistically shaped frequency distribution for temperature, especially at the tails, is related to its fidelity in simulating LMSPs. Each ensemble member is ranked for its ability to reproduce LSMPs associated with observed warm and cold extremes, identifying systematically high performing RCMs and the GCMs that provide superior boundary forcing. The methodology developed here provides a framework for identifying regions where further process-based evaluation would improve the understanding of simulation error and help guide future model improvement and downscaling efforts.

The Extreme Ultraviolet Explorer science instruments development - Lessons learned

NASA Technical Reports Server (NTRS)

Malina, Roger F.; Battel, S.

1991-01-01

The science instruments development project for the Extreme Ultraviolet Explorer (EUVE) satellite is reviewed. Issues discussed include the philosophical basis of the program, the establishment of a tight development team, the approach to planning and phasing activities, the handling of the most difficult technical problems, and the assessment of the work done during the preimplemntation period of the project.

Accurate high-speed liquid handling of very small biological samples.

PubMed

Schober, A; Günther, R; Schwienhorst, A; Döring, M; Lindemann, B F

1993-08-01

Molecular biology techniques require the accurate pipetting of buffers and solutions with volumes in the microliter range. Traditionally, hand-held pipetting devices are used to fulfill these requirements, but many laboratories have also introduced robotic workstations for the handling of liquids. Piston-operated pumps are commonly used in manually as well as automatically operated pipettors. These devices cannot meet the demands for extremely accurate pipetting of very small volumes at the high speed that would be necessary for certain applications (e.g., in sequencing projects with high throughput). In this paper we describe a technique for the accurate microdispensation of biochemically relevant solutions and suspensions with the aid of a piezoelectric transducer. It is suitable for liquids of a viscosity between 0.5 and 500 milliPascals. The obtainable drop sizes range from 5 picoliters to a few nanoliters with up to 10,000 drops per second. Liquids can be dispensed in single or accumulated drops to handle a wide volume range. The system proved to be excellently suitable for the handling of biological samples. It did not show any detectable negative impact on the biological function of dissolved or suspended molecules or particles.

Solar Power Generation in Extreme Space Environments

NASA Technical Reports Server (NTRS)

Elliott, Frederick W.; Piszczor, Michael F.

2016-01-01

The exploration of space requires power for guidance, navigation, and control; instrumentation; thermal control; communications and data handling; and many subsystems and activities. Generating sufficient and reliable power in deep space through the use of solar arrays becomes even more challenging as solar intensity decreases and high radiation levels begin to degrade the performance of photovoltaic devices. The Extreme Environments Solar Power (EESP) project goal is to develop advanced photovoltaic technology to address these challenges.

A Long Expected Party — The First Stone Ceremony for the Extremely Large Telescope

NASA Astrophysics Data System (ADS)

de Zeeuw, T.; Comerón, F.; Tamai, R.

2017-06-01

The ceremony to seal the time capsule, signalling the beginning of construction of the dome and main telescope structure for the Extremely Large Telescope, took place at the Paranal Observatory on 26 May 2017, in the presence of the President of Chile, Michelle Bachelet and many international guests. Owing to high winds, the ceremony could not take place as planned on the levelled site on Cerro Armazones, but instead was held at the Paranal Residencia. A brief report of the event and its organisation is presented, and the welcome speech by the ESO Director General is included.

Analysis of the dependence of extreme rainfalls

NASA Astrophysics Data System (ADS)

Padoan, Simone; Ancey, Christophe; Parlange, Marc

2010-05-01

The aim of spatial analysis is to quantitatively describe the behavior of environmental phenomena such as precipitation levels, wind speed or daily temperatures. A number of generic approaches to spatial modeling have been developed[1], but these are not necessarily ideal for handling extremal aspects given their focus on mean process levels. The areal modelling of the extremes of a natural process observed at points in space is important in environmental statistics; for example, understanding extremal spatial rainfall is crucial in flood protection. In light of recent concerns over climate change, the use of robust mathematical and statistical methods for such analyses has grown in importance. Multivariate extreme value models and the class of maxstable processes [2] have a similar asymptotic motivation to the univariate Generalized Extreme Value (GEV) distribution , but providing a general approach to modeling extreme processes incorporating temporal or spatial dependence. Statistical methods for max-stable processes and data analyses of practical problems are discussed by [3] and [4]. This work illustrates methods to the statistical modelling of spatial extremes and gives examples of their use by means of a real extremal data analysis of Switzerland precipitation levels. [1] Cressie, N. A. C. (1993). Statistics for Spatial Data. Wiley, New York. [2] de Haan, L and Ferreria A. (2006). Extreme Value Theory An Introduction. Springer, USA. [3] Padoan, S. A., Ribatet, M and Sisson, S. A. (2009). Likelihood-Based Inference for Max-Stable Processes. Journal of the American Statistical Association, Theory & Methods. In press. [4] Davison, A. C. and Gholamrezaee, M. (2009), Geostatistics of extremes. Journal of the Royal Statistical Society, Series B. To appear.

Tape tracking and handling for magnetic tape recorders. [aboard spacecraft

NASA Technical Reports Server (NTRS)

Paroby, W.; Disilvestre, R.

1975-01-01

One of the critical performance and life limiting elements of a spacecraft tape recorder instrumentation system which has received little attention in technical literature is magnetic tape tracking and handling technology. This technology is required to understand how to gently transfer tape from one reel to another with proper alignment and a desirable uniform velocity at the read and write transducer heads. The increased demand for high data rate (i.e., multi-track spacecraft recording instrumentation systems), coupled with performance under extreme environmental conditions, requires a thorough knowledge of the various parameters which establish an optimum designed tape tracking and handling system. Stress analysis techniques are required to evaluate these parameters substantiated with test tape tracking data, to show the effect of each parameter on a tape recorder instrumentation tracking system. The technology is applicable to ground type tape recorders where the detrimental effects of edge guidance can be eliminated.

Double PCL sign does not always indicate a bucket-handle tear of medial meniscus.

PubMed

Liu, Chen; Zheng, Hua Yong; Huang, Yan; Li, Hai Peng; Wu, Han; Sun, Tian Sheng; Yao, Jian Hua

2016-09-01

The discoid medial meniscus is an extremely rare anomaly. Bilateral discoid medial menisci are much more rare but intermittently reported. We report the first case of bilateral discoid medial menisci with positive double PCL sign, which typically indicates a bucket-handle tear of medial meniscus. A literature review was also conducted on bilateral discoid medial menisci.

Investigating NARCCAP Precipitation Extremes via Bivariate Extreme Value Theory (Invited)

NASA Astrophysics Data System (ADS)

Weller, G. B.; Cooley, D. S.; Sain, S. R.; Bukovsky, M. S.; Mearns, L. O.

2013-12-01

We introduce methodology from statistical extreme value theory to examine the ability of reanalysis-drive regional climate models to simulate past daily precipitation extremes. Going beyond a comparison of summary statistics such as 20-year return values, we study whether the most extreme precipitation events produced by climate model simulations exhibit correspondence to the most extreme events seen in observational records. The extent of this correspondence is formulated via the statistical concept of tail dependence. We examine several case studies of extreme precipitation events simulated by the six models of the North American Regional Climate Change Assessment Program (NARCCAP) driven by NCEP reanalysis. It is found that the NARCCAP models generally reproduce daily winter precipitation extremes along the Pacific coast quite well; in contrast, simulation of past daily summer precipitation extremes in a central US region is poor. Some differences in the strength of extremal correspondence are seen in the central region between models which employ spectral nudging and those which do not. We demonstrate how these techniques may be used to draw a link between extreme precipitation events and large-scale atmospheric drivers, as well as to downscale extreme precipitation simulated by a future run of a regional climate model. Specifically, we examine potential future changes in the nature of extreme precipitation along the Pacific coast produced by the pineapple express (PE) phenomenon. A link between extreme precipitation events and a "PE Index" derived from North Pacific sea-surface pressure fields is found. This link is used to study PE-influenced extreme precipitation produced by a future-scenario climate model run.

Assessing the impact of climate and land use changes on extreme floods in a large tropical catchment

NASA Astrophysics Data System (ADS)

Jothityangkoon, Chatchai; Hirunteeyakul, Chow; Boonrawd, Kowit; Sivapalan, Murugesu

2013-05-01

In the wake of the recent catastrophic floods in Thailand, there is considerable concern about the safety of large dams designed and built some 50 years ago. In this paper a distributed rainfall-runoff model appropriate for extreme flood conditions is used to generate revised estimates of the Probable Maximum Flood (PMF) for the Upper Ping River catchment (area 26,386 km2) in northern Thailand, upstream of location of the large Bhumipol Dam. The model has two components: a continuous water balance model based on a configuration of parameters estimated from climate, soil and vegetation data and a distributed flood routing model based on non-linear storage-discharge relationships of the river network under extreme flood conditions. The model is implemented under several alternative scenarios regarding the Probable Maximum Precipitation (PMP) estimates and is also used to estimate the potential effects of both climate change and land use and land cover changes on the extreme floods. These new estimates are compared against estimates using other hydrological models, including the application of the original prediction methods under current conditions. Model simulations and sensitivity analyses indicate that a reasonable Probable Maximum Flood (PMF) at the dam site is 6311 m3/s, which is only slightly higher than the original design flood of 6000 m3/s. As part of an uncertainty assessment, the estimated PMF is sensitive to the design method, input PMP, land use changes and the floodplain inundation effect. The increase of PMP depth by 5% can cause a 7.5% increase in PMF. Deforestation by 10%, 20%, 30% can result in PMF increases of 3.1%, 6.2%, 9.2%, respectively. The modest increase of the estimated PMF (to just 6311 m3/s) in spite of these changes is due to the factoring of the hydraulic effects of trees and buildings on the floodplain as the flood situation changes from normal floods to extreme floods, when over-bank flows may be the dominant flooding process, leading

Prototype of a laser guide star wavefront sensor for the Extremely Large Telescope

NASA Astrophysics Data System (ADS)

Patti, M.; Lombini, M.; Schreiber, L.; Bregoli, G.; Arcidiacono, C.; Cosentino, G.; Diolaiti, E.; Foppiani, I.

2018-06-01

The new class of large telescopes, like the future Extremely Large Telescope (ELT), are designed to work with a laser guide star (LGS) tuned to a resonance of atmospheric sodium atoms. This wavefront sensing technique presents complex issues when applied to big telescopes for many reasons, mainly linked to the finite distance of the LGS, the launching angle, tip-tilt indetermination and focus anisoplanatism. The implementation of a laboratory prototype for the LGS wavefront sensor (WFS) at the beginning of the phase study of MAORY (Multi-conjugate Adaptive Optics Relay) for ELT first light has been indispensable in investigating specific mitigation strategies for the LGS WFS issues. This paper presents the test results of the LGS WFS prototype under different working conditions. The accuracy within which the LGS images are generated on the Shack-Hartmann WFS has been cross-checked with the MAORY simulation code. The experiments show the effect of noise on centroiding precision, the impact of LGS image truncation on wavefront sensing accuracy as well as the temporal evolution of the sodium density profile and LGS image under-sampling.

Survival in extreme environments - on the current knowledge of adaptations in tardigrades.

PubMed

Møbjerg, N; Halberg, K A; Jørgensen, A; Persson, D; Bjørn, M; Ramløv, H; Kristensen, R M

2011-07-01

Tardigrades are microscopic animals found worldwide in aquatic as well as terrestrial ecosystems. They belong to the invertebrate superclade Ecdysozoa, as do the two major invertebrate model organisms: Caenorhabditis elegans and Drosophila melanogaster. We present a brief description of the tardigrades and highlight species that are currently used as models for physiological and molecular investigations. Tardigrades are uniquely adapted to a range of environmental extremes. Cryptobiosis, currently referred to as a reversible ametabolic state induced by e.g. desiccation, is common especially among limno-terrestrial species. It has been shown that the entry and exit of cryptobiosis may involve synthesis of bioprotectants in the form of selective carbohydrates and proteins as well as high levels of antioxidant enzymes and other free radical scavengers. However, at present a general scheme of mechanisms explaining this phenomenon is lacking. Importantly, recent research has shown that tardigrades even in their active states may be extremely tolerant to environmental stress, handling extreme levels of ionizing radiation, large fluctuation in external salinity and avoiding freezing by supercooling to below -20 °C, presumably relying on efficient DNA repair mechanisms and osmoregulation. This review summarizes the current knowledge on adaptations found among tardigrades, and presents new data on tardigrade cell numbers and osmoregulation. © 2011 The Authors. Acta Physiologica © 2011 Scandinavian Physiological Society.

Extremely large magnetoresistance and Kohler's rule in PdSn 4 : A complete study of thermodynamic, transport, and band-structure properties

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jo, Na Hyun; Wu, Yun; Wang, Lin-Lin

The recently discovered material PtSn 4 is known to exhibit extremely large magnetoresistance (XMR) that also manifests Dirac arc nodes on the surface. PdSn 4 is isostructural to PtSn 4 with the same electron count. Here, we report on the physical properties of high-quality single crystals of PdSn 4 including specific heat, temperature- and magnetic-field-dependent resistivity and magnetization, and electronic band-structure properties obtained from angle-resolved photoemission spectroscopy (ARPES). We observe that PdSn 4 has physical properties that are qualitatively similar to those of PtSn 4 , but find also pronounced differences. Importantly, the Dirac arc node surface state of PtSnmore » 4 is gapped out for PdSn 4. By comparing these similar compounds, we address the origin of the extremely large magnetoresistance in PdSn 4 and PtSn 4; based on detailed analysis of the magnetoresistivity ρ ( H , T ) , we conclude that neither the carrier compensation nor the Dirac arc node surface state are the primary reason for the extremely large magnetoresistance. On the other hand, we also find that, surprisingly, Kohler's rule scaling of the magnetoresistance, which describes a self-similarity of the field-induced orbital electronic motion across different length scales and is derived for a simple electronic response of metals to an applied magnetic field is obeyed over the full range of temperatures and field strengths that we explore.« less

Extremely large magnetoresistance and Kohler's rule in PdSn 4 : A complete study of thermodynamic, transport, and band-structure properties

DOE PAGES

Jo, Na Hyun; Wu, Yun; Wang, Lin-Lin; ...

2017-10-27

The recently discovered material PtSn 4 is known to exhibit extremely large magnetoresistance (XMR) that also manifests Dirac arc nodes on the surface. PdSn 4 is isostructural to PtSn 4 with the same electron count. Here, we report on the physical properties of high-quality single crystals of PdSn 4 including specific heat, temperature- and magnetic-field-dependent resistivity and magnetization, and electronic band-structure properties obtained from angle-resolved photoemission spectroscopy (ARPES). We observe that PdSn 4 has physical properties that are qualitatively similar to those of PtSn 4 , but find also pronounced differences. Importantly, the Dirac arc node surface state of PtSnmore » 4 is gapped out for PdSn 4. By comparing these similar compounds, we address the origin of the extremely large magnetoresistance in PdSn 4 and PtSn 4; based on detailed analysis of the magnetoresistivity ρ ( H , T ) , we conclude that neither the carrier compensation nor the Dirac arc node surface state are the primary reason for the extremely large magnetoresistance. On the other hand, we also find that, surprisingly, Kohler's rule scaling of the magnetoresistance, which describes a self-similarity of the field-induced orbital electronic motion across different length scales and is derived for a simple electronic response of metals to an applied magnetic field is obeyed over the full range of temperatures and field strengths that we explore.« less

Rain Characteristics and Large-Scale Environments of Precipitation Objects with Extreme Rain Volumes from TRMM Observations

NASA Technical Reports Server (NTRS)

Zhou, Yaping; Lau, William K M.; Liu, Chuntao

2013-01-01

This study adopts a "precipitation object" approach by using 14 years of Tropical Rainfall Measuring Mission (TRMM) Precipitation Feature (PF) and National Centers for Environmental Prediction (NCEP) reanalysis data to study rainfall structure and environmental factors associated with extreme heavy rain events. Characteristics of instantaneous extreme volumetric PFs are examined and compared to those of intermediate and small systems. It is found that instantaneous PFs exhibit a much wider scale range compared to the daily gridded precipitation accumulation range. The top 1% of the rainiest PFs contribute over 55% of total rainfall and have 2 orders of rain volume magnitude greater than those of the median PFs. We find a threshold near the top 10% beyond which the PFs grow exponentially into larger, deeper, and colder rain systems. NCEP reanalyses show that midlevel relative humidity and total precipitable water increase steadily with increasingly larger PFs, along with a rapid increase of 500 hPa upward vertical velocity beyond the top 10%. This provides the necessary moisture convergence to amplify and sustain the extreme events. The rapid increase in vertical motion is associated with the release of convective available potential energy (CAPE) in mature systems, as is evident in the increase in CAPE of PFs up to 10% and the subsequent dropoff. The study illustrates distinct stages in the development of an extreme rainfall event including: (1) a systematic buildup in large-scale temperature and moisture, (2) a rapid change in rain structure, (3) explosive growth of the PF size, and (4) a release of CAPE before the demise of the event.

Handling and restraint.

PubMed

Donovan, John; Brown, Patricia

2006-07-01

For the safety of the handler and the animal, proper methods for handling and restraining laboratory animals should be followed. Improper handling can result in increased stress and injury to the animal. In addition, the handler risks injury from bite wounds or scratches inflicted when the animal becomes fearful or anxious. By using sure, direct movements with a determined attitude, the animal can be easily handled and restrained. Animals can be restrained either manually or in a plastic restrainer. The protocols in this unit describe handling and manual restraint of mice, rats, hamsters, and rabbits. Alternate protocols describe restraint using the plastic restrainer.

Handling and restraint.

PubMed

Donovan, John; Brown, Patricia

2004-09-01

For the safety of the handler and the animal, proper methods for handling and restraining laboratory animals should be followed. Improper handling can result in increased stress and injury to the animal. In addition, the handler risks injury from bite wounds or scratches inflicted when the animal becomes fearful or anxious. By using sure, direct movements with a determined attitude, the animal can be easily handled and restrained. Animals can be restrained either manually or in a plastic restrainer. The protocols in this unit describe handling and manual restraint of mice, rats, hamsters, and rabbits. Alternate protocols describe restraint using the plastic restrainer.

Ride quality sensitivity to SAS control law and to handling quality variations

NASA Technical Reports Server (NTRS)

Roberts, P. A.; Schmidt, D. K.; Swaim, R. L.

1976-01-01

The RQ trends which large flexible aircraft exhibit under various parameterizations of control laws and handling qualities are discussed. A summary of the assumptions and solution technique, a control law parameterization review, a discussion of ride sensitivity to handling qualities, and the RQ effects generated by implementing relaxed static stability configurations are included.

Protection efficiency of a standard compliant EUV reticle handling solution

NASA Astrophysics Data System (ADS)

He, Long; Lystad, John; Wurm, Stefan; Orvek, Kevin; Sohn, Jaewoong; Ma, Andy; Kearney, Patrick; Kolbow, Steve; Halbmaier, David

2009-03-01

For successful implementation of extreme ultraviolet lithography (EUVL) technology for late cycle insertion at 32 nm half-pitch (hp) and full introduction for 22 nm hp high volume production, the mask development infrastructure must be in place by 2010. The central element of the mask infrastructure is contamination-free reticle handling and protection. Today, the industry has already developed and balloted an EUV pod standard for shipping, transporting, transferring, and storing EUV masks. We have previously demonstrated that the EUV pod reticle handling method represents the best approach in meeting EUVL high volume production requirements, based on then state-of-the-art inspection capability at ~53nm polystyrene latex (PSL) equivalent sensitivity. In this paper, we will present our latest data to show defect-free reticle handling is achievable down to 40 nm particle sizes, using the same EUV pod carriers as in the previous study and the recently established world's most advanced defect inspection capability of ~40 nm SiO2 equivalent sensitivity. The EUV pod is a worthy solution to meet EUVL pilot line and pre-production exposure tool development requirements. We will also discuss the technical challenges facing the industry in refining the EUV pod solution to meet 22 nm hp EUVL production requirements and beyond.

Ergonomics and comfort in lawn mower handle positioning: An evaluation of handle geometry.

PubMed

Lowndes, Bethany R; Heald, Elizabeth A; Hallbeck, M Susan

2015-11-01

Hand operation accompanied with any combination of large forces, awkward positions and repetition may lead to upper limb injury or illness and may be exacerbated by vibration. Commercial lawn mowers expose operators to these factors during actuation of hand controls and therefore may be a health concern. A nontraditional lawn mower control system may decrease upper limb illnesses and injuries through more neutral hand and body positioning. This study compared maximum grip strength in twelve different orientations (3 grip spans and 4 positions) and evaluated self-described comfortable handle positions. The results displayed force differences between nontraditional (X) and both vertical (V) and pistol (P) positions (p < 0.0001) and among the different grip spans (p < 0.0001). Based on these results, recommended designs should incorporate a tilt between 45 and 70°, handle rotations between 48 and 78°, and reduced force requirements or decreased grip spans to improve user health and comfort. Copyright © 2015 Elsevier Ltd and The Ergonomics Society. All rights reserved.

LACIE data-handling techniques

NASA Technical Reports Server (NTRS)

Waits, G. H. (Principal Investigator)

1979-01-01

Techniques implemented to facilitate processing of LANDSAT multispectral data between 1975 and 1978 are described. The data that were handled during the large area crop inventory experiment and the storage mechanisms used for the various types of data are defined. The overall data flow, from the placing of the LANDSAT orders through the actual analysis of the data set, is discussed. An overview is provided of the status and tracking system that was developed and of the data base maintenance and operational task. The archiving of the LACIE data is explained.

Techniques that Link Extreme Events to the Large Scale, Applied to California Heat Waves

NASA Astrophysics Data System (ADS)

Grotjahn, R.

2015-12-01

Understanding the mechanisms how Californian Central Valley (CCV) summer extreme hot spells develop is very important since the events have major impacts on the economy and human safety. Results from a series of CCV heat wave studies will be presented, emphasizing the techniques used. Key larger scale elements are identified statistically that are also consistent with synoptic and dynamic understanding of what must be present during extreme heat. Beyond providing a clear synoptic explanation, these key elements have high predictability, in part because soil moisture has little annual variation in the heavily-irrigated CCV. In turn, the predictability naturally leads to an effective tool to assess climate model simulation of these heat waves in historical and future climate scenarios. (Does the model develop extreme heat for the correct reasons?) Further work identified that these large scale elements arise in two quite different ways: one from expansion southwestward of a pre-existing heat wave in southwest Canada, the other formed in place from parcels traversing the North Pacific. The pre-existing heat wave explains an early result showing correlation between heat waves in Sacramento California, and other locations along the US west coast, including distant Seattle Washington. CCV heat waves can be preceded by unusually strong tropical Indian Ocean and Indonesian convection, this partial link may occur through an Asian subtropical jet wave guide. Another link revealed by diagnostics is a middle and higher latitude source of wave activity in Siberia and East Asia that also leads to the development of the CCV heat wave. This talk will address as many of these results and the tools used to obtain them as is reasonable within the available time.

Large-scale drivers of local precipitation extremes in convection-permitting climate simulations

NASA Astrophysics Data System (ADS)

Chan, Steven C.; Kendon, Elizabeth J.; Roberts, Nigel M.; Fowler, Hayley J.; Blenkinsop, Stephen

2016-04-01

The Met Office 1.5-km UKV convective-permitting models (CPM) is used to downscale present-climate and RCP8.5 60-km HadGEM3 GCM simulations. Extreme UK hourly precipitation intensities increase with local near-surface temperatures and humidity; for temperature, the simulated increase rate for the present-climate simulation is about 6.5% K**-1, which is consistent with observations and theoretical expectations. While extreme intensities are higher in the RCP8.5 simulation as higher temperatures are sampled, there is a decline at the highest temperatures due to circulation and relative humidity changes. Extending the analysis to the broader synoptic scale, it is found that circulation patterns, as diagnosed by MSLP or circulation type, play an increased role in the probability of extreme precipitation in the RCP8.5 simulation. Nevertheless for both CPM simulations, vertical instability is the principal driver for extreme precipitation.

Occupational health and safety aspects of animal handling in dairy production.

PubMed

Lindahl, Cecilia; Lundqvist, Peter; Hagevoort, G Robert; Lunner Kolstrup, Christina; Douphrate, David I; Pinzke, Stefan; Grandin, Temple

2013-01-01

Livestock handling in dairy production is associated with a number of health and safety issues. A large number of fatal and nonfatal injuries still occur when handling livestock. The many animal handling tasks on a dairy farm include moving cattle between different locations, vaccination, administration of medication, hoof care, artificial insemination, ear tagging, milking, and loading onto trucks. There are particular problems with bulls, which continue to cause considerable numbers of injuries and fatalities in dairy production. In order to reduce the number of injuries during animal handling on dairy farms, it is important to understand the key factors in human-animal interactions. These include handler attitudes and behavior, animal behavior, and fear in cows. Care when in close proximity to the animal is the key for safe handling, including knowledge of the flight zone, and use of the right types of tools and suitable restraint equipment. Thus, in order to create safe working conditions during livestock handling, it is important to provide handlers with adequate training and to establish sound safety management procedures on the farm.

Development of Handling Qualities Criteria for Rotorcraft with Externally Slung Loads

NASA Technical Reports Server (NTRS)

Hoh, Roger H.; Heffley, Robert K.; Mitchell, David G.

2006-01-01

Piloted simulations were performed on the NASA-Ames Vertical Motion Simulator (VMS) to explore handling qualities issues for large cargo helicopters, particularly focusing on external slung load operations. The purpose of this work was based upon the need to include handling qualities criteria for cargo helicopters in an upgrade to the U.S. Army's rotorcraft handling qualities specification, Aeronautical Design Standard-33 (ADS-33E-PRF). From the VMS results, handling qualities criteria were developed fro cargo helicopters carrying external slung loads in the degraded visual environment (DVE). If satisfied, these criteria provide assurance that the handling quality rating (HQR) will be 4 or better for operations in the DVE, and with a load mass ratio of 0.33 or less. For lighter loads, flying qualities were found to be less dependent on the load geometry and therefore the significance of the criteria is less. For heavier loads, meeting the criteria ensures the best possible handling qualities, albeit Level 2 for load mass ratios greater than 0.33.

Review of the Need for a Large-scale Test Facility for Research on the Effects of Extreme Winds on Structures

DOE Office of Scientific and Technical Information (OSTI.GOV)

R. G. Little

1999-03-01

The Idaho National Engineering and Environmental Laboratory (INEEL), through the US Department of Energy (DOE), has proposed that a large-scale wind test facility (LSWTF) be constructed to study, in full-scale, the behavior of low-rise structures under simulated extreme wind conditions. To determine the need for, and potential benefits of, such a facility, the Idaho Operations Office of the DOE requested that the National Research Council (NRC) perform an independent assessment of the role and potential value of an LSWTF in the overall context of wind engineering research. The NRC established the Committee to Review the Need for a Large-scale Testmore » Facility for Research on the Effects of Extreme Winds on Structures, under the auspices of the Board on Infrastructure and the Constructed Environment, to perform this assessment. This report conveys the results of the committee's deliberations as well as its findings and recommendations. Data developed at large-scale would enhanced the understanding of how structures, particularly light-frame structures, are affected by extreme winds (e.g., hurricanes, tornadoes, sever thunderstorms, and other events). With a large-scale wind test facility, full-sized structures, such as site-built or manufactured housing and small commercial or industrial buildings, could be tested under a range of wind conditions in a controlled, repeatable environment. At this time, the US has no facility specifically constructed for this purpose. During the course of this study, the committee was confronted by three difficult questions: (1) does the lack of a facility equate to a need for the facility? (2) is need alone sufficient justification for the construction of a facility? and (3) would the benefits derived from information produced in an LSWTF justify the costs of producing that information? The committee's evaluation of the need and justification for an LSWTF was shaped by these realities.« less

Design and evaluation of a new ergonomic handle for instruments in minimally invasive surgery.

PubMed

Sancibrian, Ramon; Gutierrez-Diez, María C; Torre-Ferrero, Carlos; Benito-Gonzalez, Maria A; Redondo-Figuero, Carlos; Manuel-Palazuelos, Jose C

2014-05-01

Laparoscopic surgery techniques have been demonstrated to provide massive benefits to patients. However, surgeons are subjected to hardworking conditions because of the poor ergonomic design of the instruments. In this article, a new ergonomic handle design is presented. This handle is designed using ergonomic principles, trying to provide both more intuitive manipulation of the instrument and a shape that reduces the high-pressure zones in the contact with the surgeon's hand. The ergonomic characteristics of the new handle were evaluated using objective and subjective studies. The experimental evaluation was performed using 28 volunteers by means of the comparison of the new handle with the ring-handle (RH) concept in an instrument available on the market. The volunteers' muscle activation and motions of the hand, wrist, and arm were studied while they performed different tasks. The data measured in the experiment include electromyography and goniometry values. The results obtained from the subjective analysis reveal that most volunteers (64%) preferred the new prototype to the RH, reporting less pain and less difficulty to complete the tasks. The results from the objective study reveal that the hyperflexion of the wrist required for the manipulation of the instrument is strongly reduced. The new ergonomic handle not only provides important ergonomic advantages but also improves the efficiency when completing the tasks. Compared with RH instruments, the new prototype reduced the high-pressure areas and the extreme motions of the wrist. Copyright © 2014 Elsevier Inc. All rights reserved.

Handling a Large Collection of PDF Documents

EPA Pesticide Factsheets

You have several options for making a large collection of PDF documents more accessible to your audience: avoid uploading altogether, use multiple document pages, and use document IDs as anchors for direct links within a document page.

Origin of the extremely large magnetoresistance in the semimetal YSb

DOE PAGES

Xu, J.; Ghimire, N. J.; Jiang, J. S.; ...

2017-08-29

Extremely large magnetoresistance (XMR) was recently discovered in YSb but its origin, along with that of many other XMR materials, is an active subject of debate. Here we demonstrate that YSb, with a cubic crystalline lattice and anisotropic bulk electron Fermi pockets, can be an excellent candidate for revealing the origin of XMR. We carried out angle dependent Shubnikov – de Haas quantum oscillation measurements to determine the volume and shape of the Fermi pockets. In addition, by investigating both Hall and longitudinal magnetoresistivities, we reveal that the origin of XMR in YSb lies in its carrier high mobility withmore » a diminishing Hall factor that is obtained from the ratio of the Hall and longitudinal magentoresistivities. The high mobility leads to a strong magnetic field dependence of the longitudinal magnetoconductivity while a diminishing Hall factor reveals the latent XMR hidden in the longitudinal magnetoconductivity whose inverse has a nearly quadratic magnetic-field dependence. The Hall factor highlights the deviation of the measured magnetoresistivity from its full potential value and provides a general formulation to reveal the origin of XMR behavior in high mobility materials and of nonsaturating MR behavior as a whole. Our approach can be readily applied to other XMR materials.« less

Claims incidence of work-related disorders of the upper extremities: Washington state, 1987 through 1995.

PubMed

Silverstein, B; Welp, E; Nelson, N; Kalat, J

1998-12-01

This study examined the claim incidence rate, cost, and industry distribution of work-related upper extremity disorders in Washington. Washington State Fund workers' compensation claims from 1987 to 1995 were abstracted and categorized into general and specific disorders of gradual or sudden onset. Accepted claims included 100,449 for hand/wrist disorders (incidence rate: 98.2/10,000 full-time equivalents; carpal tunnel syndrome rate: 27.3), 30,468 for elbow disorders (incidence rate: 29.7; epicondylitis rate: 11.7), and 55,315 for shoulder disorders (incidence rate: 54.0; rotator cuff syndrome rate: 19.9). Average direct workers' compensation claims costs (medical treatment and indemnity) were $15,790 (median: $6774) for rotator cuff syndrome, $12,794 for carpal tunnel syndrome (median: $4190), and $6593 for epicondylitis (median: $534). Construction and food processing were among the industries with the highest rate ratios for all disorders (> 4.0). Upper extremity disorders represent a large and costly problem in Washington State industry. Industries characterized by manual handling and repetitive work have high rate ratios. The contingent workforce appears to be at high risk.

Changes in US extreme sea levels and the role of large scale climate variations

NASA Astrophysics Data System (ADS)

Wahl, T.; Chambers, D. P.

2015-12-01

We analyze a set of 20 tide gauge records covering the contiguous United States (US) coastline and the period from 1929 to 2013 to identify long-term trends and multi-decadal variations in extreme sea levels (ESLs) relative to changes in mean sea level (MSL). Significant but small long-term trends in ESLs above/below MSL are found at individual sites along most coastline stretches, but are mostly confined to the southeast coast and the winter season when storm surges are primarily driven by extra-tropical cyclones. We identify six regions with broadly coherent and considerable multi-decadal ESL variations unrelated to MSL changes. Using a quasi-non-stationary extreme value analysis approach we show that the latter would have caused variations in design relevant return water levels (RWLs; 50 to 200 year return periods) ranging from ~10 cm to as much as 110 cm across the six regions. To explore the origin of these temporal changes and the role of large-scale climate variability we develop different sets of simple and multiple linear regression models with RWLs as dependent variables and climate indices, or tailored (toward the goal of predicting multi-decadal RWL changes) versions of them, and wind stress curl as independent predictors. The models, after being tested for spatial and temporal stability, explain up to 97% of the observed variability at individual sites and almost 80% on average. Using the model predictions as covariates for the quasi-non-stationary extreme value analysis also significantly reduces the range of change in the 100-year RWLs over time, turning a non-stationary process into a stationary one. This highlights that the models - when used with regional and global climate model output of the predictors - should also be capable of projecting future RWL changes to be used by decision makers for improved flood preparedness and long-term resiliency.

Extremely Large Magnetoresistance in a Topological Semimetal Candidate Pyrite PtBi2

NASA Astrophysics Data System (ADS)

Gao, Wenshuai; Hao, Ningning; Zheng, Fa-Wei; Ning, Wei; Wu, Min; Zhu, Xiangde; Zheng, Guolin; Zhang, Jinglei; Lu, Jianwei; Zhang, Hongwei; Xi, Chuanying; Yang, Jiyong; Du, Haifeng; Zhang, Ping; Zhang, Yuheng; Tian, Mingliang

2017-06-01

While pyrite-type PtBi2 with a face-centered cubic structure has been predicted to be a three-dimensional (3D) Dirac semimetal, experimental study of its physical properties remains absent. Here we report the angular-dependent magnetoresistance measurements of a PtBi2 single crystal under high magnetic fields. We observed extremely large unsaturated magnetoresistance (XMR) up to (11.2 ×106)% at T =1.8 K in a magnetic field of 33 T, which is comparable to the previously reported Dirac materials, such as WTe2 , LaSb, and NbP. The crystals exhibit an ultrahigh mobility and significant Shubnikov-de Hass quantum oscillations with a nontrivial Berry phase. The analysis of Hall resistivity indicates that the XMR can be ascribed to the nearly compensated electron and hole. Our experimental results associated with the ab initio calculations suggest that pyrite PtBi2 is a topological semimetal candidate that might provide a platform for exploring topological materials with XMR in noble metal alloys.

Evaluating the ClimEx Single Model Large Ensemble in Comparison with EURO-CORDEX Results of Seasonal Means and Extreme Precipitation Indicators

NASA Astrophysics Data System (ADS)

von Trentini, F.; Schmid, F. J.; Braun, M.; Brisette, F.; Frigon, A.; Leduc, M.; Martel, J. L.; Willkofer, F.; Wood, R. R.; Ludwig, R.

2017-12-01

Meteorological extreme events seem to become more frequent in the present and future, and a seperation of natural climate variability and a clear climate change effect on these extreme events gains more and more interest. Since there is only one realisation of historical events, natural variability in terms of very long timeseries for a robust statistical analysis is not possible with observation data. A new single model large ensemble (SMLE), developed for the ClimEx project (Climate change and hydrological extreme events - risks and perspectives for water management in Bavaria and Québec) is supposed to overcome this lack of data by downscaling 50 members of the CanESM2 (RCP 8.5) with the Canadian CRCM5 regional model (using the EURO-CORDEX grid specifications) for timeseries of 1950-2099 each, resulting in 7500 years of simulated climate. This allows for a better probabilistic analysis of rare and extreme events than any preceding dataset. Besides seasonal sums, several extreme indicators like R95pTOT, RX5day and others are calculated for the ClimEx ensemble and several EURO-CORDEX runs. This enables us to investigate the interaction between natural variability (as it appears in the CanESM2-CRCM5 members) and a climate change signal of those members for past, present and future conditions. Adding the EURO-CORDEX results to this, we can also assess the role of internal model variability (or natural variability) in climate change simulations. A first comparison shows similar magnitudes of variability of climate change signals between the ClimEx large ensemble and the CORDEX runs for some indicators, while for most indicators the spread of the SMLE is smaller than the spread of different CORDEX models.

Extreme Temperature Regimes during the Cool Season and their Associated Large-Scale Circulations

NASA Astrophysics Data System (ADS)

Xie, Z.

2015-12-01

In the cool season (November-March), extreme temperature events (ETEs) always hit the continental United States (US) and provide significant societal impacts. According to the anomalous amplitudes of the surface air temperature (SAT), there are two typical types of ETEs, e.g. cold waves (CWs) and warm waves (WWs). This study used cluster analysis to categorize both CWs and WWs into four distinct regimes respectively and investigated their associated large-scale circulations on intra-seasonal time scale. Most of the CW regimes have large areal impact over the continental US. However, the distribution of cold SAT anomalies varies apparently in four regimes. In the sea level, the four CW regimes are characterized by anomalous high pressure over North America (near and to west of cold anomaly) with different extension and orientation. As a result, anomalous northerlies along east flank of anomalous high pressure convey cold air into the continental US. To the middle troposphere, the leading two groups feature large-scale and zonally-elongated circulation anomaly pattern, while the other two regimes exhibit synoptic wavetrain pattern with meridionally elongated features. As for the WW regimes, there are some patterns symmetry and anti-symmetry with respect to CW regimes. The WW regimes are characterized by anomalous low pressure and southerlies wind over North America. The first and fourth groups are affected by remote forcing emanating from North Pacific, while the others appear mainly locally forced.

Improving Memory Error Handling Using Linux

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carlton, Michael Andrew; Blanchard, Sean P.; Debardeleben, Nathan A.

As supercomputers continue to get faster and more powerful in the future, they will also have more nodes. If nothing is done, then the amount of memory in supercomputer clusters will soon grow large enough that memory failures will be unmanageable to deal with by manually replacing memory DIMMs. "Improving Memory Error Handling Using Linux" is a process oriented method to solve this problem by using the Linux kernel to disable (offline) faulty memory pages containing bad addresses, preventing them from being used again by a process. The process of offlining memory pages simplifies error handling and results in reducingmore » both hardware and manpower costs required to run Los Alamos National Laboratory (LANL) clusters. This process will be necessary for the future of supercomputing to allow the development of exascale computers. It will not be feasible without memory error handling to manually replace the number of DIMMs that will fail daily on a machine consisting of 32-128 petabytes of memory. Testing reveals the process of offlining memory pages works and is relatively simple to use. As more and more testing is conducted, the entire process will be automated within the high-performance computing (HPC) monitoring software, Zenoss, at LANL.« less

Enabling large-scale next-generation sequence assembly with Blacklight

PubMed Central

Couger, M. Brian; Pipes, Lenore; Squina, Fabio; Prade, Rolf; Siepel, Adam; Palermo, Robert; Katze, Michael G.; Mason, Christopher E.; Blood, Philip D.

2014-01-01

Summary A variety of extremely challenging biological sequence analyses were conducted on the XSEDE large shared memory resource Blacklight, using current bioinformatics tools and encompassing a wide range of scientific applications. These include genomic sequence assembly, very large metagenomic sequence assembly, transcriptome assembly, and sequencing error correction. The data sets used in these analyses included uncategorized fungal species, reference microbial data, very large soil and human gut microbiome sequence data, and primate transcriptomes, composed of both short-read and long-read sequence data. A new parallel command execution program was developed on the Blacklight resource to handle some of these analyses. These results, initially reported previously at XSEDE13 and expanded here, represent significant advances for their respective scientific communities. The breadth and depth of the results achieved demonstrate the ease of use, versatility, and unique capabilities of the Blacklight XSEDE resource for scientific analysis of genomic and transcriptomic sequence data, and the power of these resources, together with XSEDE support, in meeting the most challenging scientific problems. PMID:25294974

Modeling, Forecasting and Mitigating Extreme Earthquakes

NASA Astrophysics Data System (ADS)

Ismail-Zadeh, A.; Le Mouel, J.; Soloviev, A.

2012-12-01

Recent earthquake disasters highlighted the importance of multi- and trans-disciplinary studies of earthquake risk. A major component of earthquake disaster risk analysis is hazards research, which should cover not only a traditional assessment of ground shaking, but also studies of geodetic, paleoseismic, geomagnetic, hydrological, deep drilling and other geophysical and geological observations together with comprehensive modeling of earthquakes and forecasting extreme events. Extreme earthquakes (large magnitude and rare events) are manifestations of complex behavior of the lithosphere structured as a hierarchical system of blocks of different sizes. Understanding of physics and dynamics of the extreme events comes from observations, measurements and modeling. A quantitative approach to simulate earthquakes in models of fault dynamics will be presented. The models reproduce basic features of the observed seismicity (e.g., the frequency-magnitude relationship, clustering of earthquakes, occurrence of extreme seismic events). They provide a link between geodynamic processes and seismicity, allow studying extreme events, influence of fault network properties on seismic patterns and seismic cycles, and assist, in a broader sense, in earthquake forecast modeling. Some aspects of predictability of large earthquakes (how well can large earthquakes be predicted today?) will be also discussed along with possibilities in mitigation of earthquake disasters (e.g., on 'inverse' forensic investigations of earthquake disasters).

Very high-resolution spectroscopy for extremely large telescopes using pupil slicing and adaptive optics.

PubMed

Beckers, Jacques M; Andersen, Torben E; Owner-Petersen, Mette

2007-03-05

Under seeing limited conditions very high resolution spectroscopy becomes very difficult for extremely large telescopes (ELTs). Using adaptive optics (AO) the stellar image size decreases proportional with the telescope diameter. This makes the spectrograph optics and hence its resolution independent of the telescope diameter. However AO for use with ELTs at visible wavelengths require deformable mirrors with many elements. Those are not likely to be available for quite some time. We propose to use the pupil slicing technique to create a number of sub-pupils each of which having its own deformable mirror. The images from all sub-pupils are combined incoherently with a diameter corresponding to the diffraction limit of the sub-pupil. The technique is referred to as "Pupil Slicing Adaptive Optics" or PSAO.

Effect of bit wear on hammer drill handle vibration and productivity.

PubMed

Antonucci, Andrea; Barr, Alan; Martin, Bernard; Rempel, David

2017-08-01

The use of large electric hammer drills exposes construction workers to high levels of hand vibration that may lead to hand-arm vibration syndrome and other musculoskeletal disorders. The aim of this laboratory study was to investigate the effect of bit wear on drill handle vibration and drilling productivity (e.g., drilling time per hole). A laboratory test bench system was used with an 8.3 kg electric hammer drill and 1.9 cm concrete bit (a typical drill and bit used in commercial construction). The system automatically advanced the active drill into aged concrete block under feed force control to a depth of 7.6 cm while handle vibration was measured according to ISO standards (ISO 5349 and 28927). Bits were worn to 4 levels by consecutive hole drilling to 4 cumulative drilling depths: 0, 1,900, 5,700, and 7,600 cm. Z-axis handle vibration increased significantly (p<0.05) from 4.8 to 5.1 m/s 2 (ISO weighted) and from 42.7-47.6 m/s 2 (unweighted) when comparing a new bit to a bit worn to 1,900 cm of cumulative drilling depth. Handle vibration did not increase further with bits worn more than 1900 cm of cumulative drilling depth. Neither x- nor y-axis handle vibration was effected by bit wear. The time to drill a hole increased by 58% for the bit with 5,700 cm of cumulative drilling depth compared to a new bit. Bit wear led to a small but significant increase in both ISO weighted and unweighted z-axis handle vibration. Perhaps more important, bit wear had a large effect on productivity. The effect on productivity will influence a worker's allowable daily drilling time if exposure to drill handle vibration is near the ACGIH Threshold Limit Value. [1] Construction contractors should implement a bit replacement program based on these findings.

Quantifying the effect of editor-author relations on manuscript handling times.

PubMed

Sarigöl, Emre; Garcia, David; Scholtes, Ingo; Schweitzer, Frank

2017-01-01

In this article we study to what extent the academic peer review process is influenced by social relations between the authors of a manuscript and the editor handling the manuscript. Taking the open access journal PlosOne as a case study, our analysis is based on a data set of more than 100,000 articles published between 2007 and 2015. Using available data on handling editor, submission and acceptance time of manuscripts, we study the question whether co-authorship relations between authors and the handling editor affect the manuscript handling time , i.e. the time taken between the submission and acceptance of a manuscript. Our analysis reveals (1) that editors handle papers co-authored by previous collaborators significantly more often than expected at random, and (2) that such prior co-author relations are significantly related to faster manuscript handling. Addressing the question whether these shorter manuscript handling times can be explained by the quality of publications, we study the number of citations and downloads which accepted papers eventually accumulate. Moreover, we consider the influence of additional (social) factors, such as the editor's experience, the topical similarity between authors and editors, as well as reciprocal citation relations between authors and editors. Our findings show that, even when correcting for other factors like time, experience, and performance, prior co-authorship relations have a large and significant influence on manuscript handling times, speeding up the editorial decision on average by 19 days.

MoTe2: An uncompensated semimetal with extremely large magnetoresistance

NASA Astrophysics Data System (ADS)

Thirupathaiah, S.; Jha, Rajveer; Pal, Banabir; Matias, J. S.; Das, P. Kumar; Sivakumar, P. K.; Vobornik, I.; Plumb, N. C.; Shi, M.; Ribeiro, R. A.; Sarma, D. D.

2017-06-01

Transition-metal dichalcogenides (WTe2 and MoTe2) have recently drawn much attention, because of the nonsaturating extremely large magnetoresistance (XMR) observed in these compounds in addition to the predictions of likely type-II Weyl semimetals. Contrary to the topological insulators or Dirac semimetals where XMR is linearly dependent on the field, in WTe2 and MoTe2 the XMR is nonlinearly dependent on the field, suggesting an entirely different mechanism. Electron-hole compensation has been proposed as a mechanism of this nonsaturating XMR in WTe2, while it is yet to be clear in the case of MoTe2 which has an identical crystal structure of WTe2 at low temperatures. In this Rapid Communication, we report low-energy electronic structure and Fermi surface topology of MoTe2 using angle-resolved photoemission spectrometry (ARPES) technique and first-principles calculations, and compare them with that of WTe2 to understand the mechanism of XMR. Our measurements demonstrate that MoTe2 is an uncompensated semimetal, contrary to WTe2 in which compensated electron-hole pockets have been identified, ruling out the applicability of charge compensation theory for the nonsaturating XMR in MoTe2. In this context, we also discuss the applicability of other existing conjectures on the XMR of these compounds.

The Influence of Extremely Large Solar Proton Events in a Changing Stratosphere. Stratospheric Influence of Solar Proton Events

NASA Technical Reports Server (NTRS)

Jackman, Charles H.; Fleming, Eric L.; Vitt, Francis M.

1999-01-01

Two periods of extremely large solar proton events (SPEs) occurred in the past thirty years, which forced significant long-term polar stratospheric changes. The August 2-10, 1972 and October 19-27, 1989 SPEs happened in stratospheres that were quite different chemically. The stratospheric chlorine levels were relatively small in 1972 (approximately 1.2 ppbv) and were fairly substantial in 1989 at about (approximately 3 ppbv). Although these SPEs produced both HO(x) and NO(y) constituents in the mesosphere and stratosphere, only the NO(y) constituents had lifetimes long enough to affect ozone for several months to years past the events. Our recently improved two-dimensional chemistry and transport atmospheric model was used to compute the effects of these gigantic SPEs in a changing stratosphere. Significant upper stratospheric ozone depletions > 10% are computed to last for a few months past these SPEs. The long-lived SPE-produced NO(y) constituents were transported to lower levels during winter after these huge SPEs and caused impacts in the middle and lower stratosphere. During periods of high halogen loading these impacts resulted in interference with the chlorine and bromine loss cycles for ozone destruction. The chemical state of the atmosphere, including the stratospheric sulfate aerosol density, substantially affected the predicted stratospheric influence of these extremely large SPEs.

Ergonomics study on the handle length and lift angle for the culinary spatula.

PubMed

Wu, Swei-Pi; Hsieh, Chang-Sheng

2002-09-01

The culinary spatula (turning shovel) is one of the most common cooking tools used in the kitchen in Asia. However, the culinary spatula has seldom been ergonomically investigated. When a person uses a spatula to cook food, the operations involve repetitive bent-wrist motions, such as dorsiflexion, palmary flexion, and radial and ulnar deviations. These movements may cause cumulative trauma disorders in the upper extremities, and in particular carpal tunnel syndrome. A poorly designed culinary spatula will be ergonomically inefficient and cause injury to the hand and wrist. The purpose of this study was to investigate the effects of spatula handle length and lift angle on food-frying, food-turning, and food-shoveling performance. Eight female subjects were tested using 16 different culinary spatulas, with four different handle lengths (20, 25, 30 and 35 cm) and four different lift angles (15 degrees, 25 degrees, 35 degrees and 45 ). The criterion measures included cooking performance, and rating of perceived exertion. The subjects ranked their preference after all of the tasks in the tests were completed. The results showed that: (1) The handle length had a significant influence on the cooking performance, and rating of perceived exertion. The optimal handle lengths for frying food, turning food, and shoveling food were 20, 25 and 25 cm, respectively. (2) The lift angle significantly affected the cooking performance, and rating of perceived exertion. The optimal lift angles for frying food, turning food, and shoveling food were 15 degrees, 15 degrees and 25 degrees, respectively. (3) Both the handle length and lift angle had significant effects on subjective preference. For the handle length, the 20 cm length was the best. For the lift angle, the 25 angle was the best. (4) In general, a spatula with a 20 cm handle length and 25 degrees lift angle was the best. A spatula with a 25 cm handle length and 15 lift angle was the second most preferred. (5) However, to

A CityGML Extension for Handling Very Large Tins

NASA Astrophysics Data System (ADS)

Kumar, K.; Ledoux, H.; Stoter, J.

2016-10-01

In addition to buildings, the terrain forms an important part of a 3D city model. Although in GIS terrains are usually represented with 2D grids, TINs are also increasingly being used in practice. One example is 3DTOP10NL, the 3D city model covering the whole of the Netherlands, which stores the relief with a constrained TIN containing more than 1 billion triangles. Due to the massive size of such datasets, the main problem that arises is: how to efficiently store and maintain them? While CityGML supports the storage of TINs, we argue in this paper that the current solution is not adequate. For instance, the 1 billion+ triangles of 3DTOP10NL require 686 GB of storage space with CityGML. Furthermore, the current solution does not store the topological relationships of the triangles, and also there are no clear mechanisms to handle several LODs. We propose in this paper a CityGML extension for the compact representation of terrains. We describe our abstract and implementation specifications (modelled in UML), and our prototype implementation to convert TINs to our CityGML structure. It increases the topological relationships that are explicitly represented, and allows us to compress up to a factor of ∼ 25 in our experiments with massive real-world terrains (more than 1 billion triangles).

Extreme-value dependence: An application to exchange rate markets

NASA Astrophysics Data System (ADS)

Fernandez, Viviana

2007-04-01

Extreme value theory (EVT) focuses on modeling the tail behavior of a loss distribution using only extreme values rather than the whole data set. For a sample of 10 countries with dirty/free float regimes, we investigate whether paired currencies exhibit a pattern of asymptotic dependence. That is, whether an extremely large appreciation or depreciation in the nominal exchange rate of one country might transmit to another. In general, after controlling for volatility clustering and inertia in returns, we do not find evidence of extreme-value dependence between paired exchange rates. However, for asymptotic-independent paired returns, we find that tail dependency of exchange rates is stronger under large appreciations than under large depreciations.

New weight-handling device for commercial oil pressure balances

NASA Astrophysics Data System (ADS)

Woo, S. Y.; Choi, I. M.; Kim, B. S.

2005-12-01

This paper presents a new device to automatically handle a large number of weights for the calibration of a pressure gauge. This newly invented weight-handling device is made for use in conjunction with a commercial oil pressure balance. Although the pressure balance is essential as a calibration tool, its use has been generally tedious and labour intensive for a long time. In particular, the process of loading a different combination of weights on the top of a piston requires repetitious manual handling for every new measurement. This inevitably leaves the operator fatigued, and sometimes causes damage to the weights due to careless handling. The newly invented automatic weight-handling device can eliminate such tedious, error-prone and wear-inducing manual weight manipulation. The device consists of a stepping motor, a drive belt, a solenoid valve, three weight-lifting assemblies and three linear-motion guide assemblies. The weight-lifting assembly is composed of a pneumatic actuator, a solid-state switch and a metal finger. It has many advantages compared with the commercial automatic weight-handling device. Firstly, it is not necessary to lift all the weights off the piston in the weight selection process, as it is in the case of the commercial device. Thus it can prevent a permanent deformation of the weight carrier. Secondly, this new device can handle a larger number of weights than the commercial one. This is because the new device adopts a different method in retaining the remaining weights in place. Another advantage of this new device is that there is no possibility of the fingers touching the surface of the weights due to the oscillation of weights. Moreover it uses the general technology of a stepping motor, and is also made up of components that are easily obtainable in the market, thereby being very economical.

Data handling and representation of freeform surfaces

NASA Astrophysics Data System (ADS)

Steinkopf, Ralf; Dick, Lars; Kopf, Tino; Gebhardt, Andreas; Risse, Stefan; Eberhardt, Ramona

2011-10-01

Freeform surfaces enable innovative optics. They are not limited by axis symmetry and hence they are almost free in design. They are used to reduce the installation space and enhance the performance of optical elements. State of the art optical design tools are computing with powerful algorithms to simulate freeform surfaces. Even new mathematical approaches are under development /1/. In consequence, new optical designs /2/ are pushing the development of manufacturing processes consequently and novel types of datasets have to proceed through the process chain /3/. The complexity of these data is the huge challenge for the data handling. Because of the asymmetrical and 3-dimensional surfaces of freeforms, large data volumes have to be created, trimmed, extended and fitted. All these processes must be performed without losing the accuracy of the original design data. Additionally, manifold types of geometries results in different kinds of mathematical representations of freeform surfaces and furthermore the used CAD/CAM tools are dealing with a set of spatial transport formats. These are all reasons why manufacture-oriented approaches for the freeform data handling are not yet sufficiently developed. This paper suggests a classification of freeform surfaces based on the manufacturing methods which are offered by diamond machining. The different manufacturing technologies, ranging from servo-turning to shaping, require a differentiated approach for the data handling process. The usage of analytical descriptions in form of splines and polynomials as well as the application of discrete descriptions like point clouds is shown in relation to the previously made classification. Advantages and disadvantages of freeform representations are discussed. Aspects of the data handling in between different process steps are pointed out and suitable exchange formats for freeform data are proposed. The described approach offers the possibility for efficient data handling from optical

Large Extremity Peripheral Nerve Repair

DTIC Science & Technology

2015-10-01

Outcomes are unsatisfactory, affecting quality of life and return to active duty. We are investigating a sutureless, light- activated technology for...on Avance® nerve graft procedure for large animal studies in Aim 3. (All PIs, Month 22) This study shows that outcomes following light- activated ...when severe injuries, complicated with limb loss, preclude the use of autograft. The demonstrated success of light- activated sealing of isograft

Large Extremity Peripheral Nerve Repair

DTIC Science & Technology

2013-10-01

can provide fixation strengths approaching that of conventional microsurgery and that the PTB repair is unlikely to be disturbed in vivo. The...of nerve wrap biomaterial during long periods of recovery associated with large nerve deficit reconstruction and long nerve grafts. As with the...PTB/xHAM wrap compared to standard (suture) of care microsurgery . Demonstrated improved nerve regeneration in a muscle mass retention model

Large Extremity Peripheral Nerve Repair

DTIC Science & Technology

2013-10-01

show that the PTB method can provide fixation strengths approaching that of conventional microsurgery and that the PTB repair is unlikely to be...biomaterial during long periods of recovery associated with large nerve deficit reconstruction and long nerve grafts. As with the human amnion nerve...functional recovery model (SFI, sciatic function index) using PTB/xHAM wrap compared to standard (suture) of care microsurgery . Demonstrated improved nerve

CARRIER/CASK HANDLING SYSTEM DESCRIPTION DOCUMENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

E.F. Loros

2000-06-23

The Carrier/Cask Handling System receives casks on railcars and legal-weight trucks (LWTs) (transporters) that transport loaded casks and empty overpacks to the Monitored Geologic Repository (MGR) from the Carrier/Cask Transport System. Casks that come to the MGR on heavy-haul trucks (HHTs) are transferred onto railcars before being brought into the Carrier/Cask Handling System. The system is the interfacing system between the railcars and LWTs and the Assembly Transfer System (ATS) and Canister Transfer System (CTS). The Carrier/Cask Handling System removes loaded casks from the cask transporters and transfers the casks to a transfer cart for either the ATS or CTS,more » as appropriate, based on cask contents. The Carrier/Cask Handling System receives the returned empty casks from the ATS and CTS and mounts the casks back onto the transporters for reshipment. If necessary, the Carrier/Cask Handling System can also mount loaded casks back onto the transporters and remove empty casks from the transporters. The Carrier/Cask Handling System receives overpacks from the ATS loaded with canisters that have been cut open and emptied and mounts the overpacks back onto the transporters for disposal. If necessary, the Carrier/Cask Handling System can also mount empty overpacks back onto the transporters and remove loaded overpacks from them. The Carrier/Cask Handling System is located within the Carrier Bay of the Waste Handling Building System. The system consists of cranes, hoists, manipulators, and supporting equipment. The Carrier/Cask Handling System is designed with the tooling and fixtures necessary for handling a variety of casks. The Carrier/Cask Handling System performance and reliability are sufficient to support the shipping and emplacement schedules for the MGR. The Carrier/Cask Handling System interfaces with the Carrier/Cask Transport System, ATS, and CTS as noted above. The Carrier/Cask Handling System interfaces with the Waste Handling Building System for

Large Extremity Peripheral Nerve Repair

DTIC Science & Technology

2013-10-01

approaching that of conventional microsurgery and that the PTB repair is unlikely to be disturbed in vivo. The results in Figure 5 were obtained with...with large nerve deficit reconstruction and long nerve grafts. As with the human amnion nerve wraps, it was important for us to confirm that, in...xHAM wrap compared to standard (suture) of care microsurgery . Demonstrated improved nerve regeneration in a muscle mass retention model

The effect of breast support and breast pain on upper-extremity kinematics during running: implications for females with large breasts.

PubMed

White, Jennifer; Mills, Chris; Ball, Nick; Scurr, Joanna

2015-01-01

The relationship between inappropriate breast support and upper-extremity kinematics for female runners is unclear. The purpose of this study was to investigate the effect of breast support and breast pain on upper-extremity kinematics during running. Eleven female recreational runners with larger breasts (UK D and E cup) completed a 7 min 20 s treadmill run (2.58 m · s(-1)) in a high and low breast support condition. Multi-planar breast and upper-extremity kinematic data were captured in each breast support condition by eight infrared cameras for 30 s towards the end of the run. Breast pain was rated at the end of each treadmill run using a numeric analogue scale. The high support bra reduced breast kinematics and decreased breast pain (P < 0.05). Upper-extremity kinematics did not differ between breast support conditions (P > 0.05), although some moderate positive correlations were found between thorax range of motion and breast kinematics (r = 0.54 to 0.73). Thorax and arm kinematics do not appear to be influenced by breast support level in female runners with large breasts. A high support bra that offers good multi-planar breast support is recommended for female runners with larger breasts to reduce breast pain.

Weather extremes in very large, high-resolution ensembles: the weatherathome experiment

NASA Astrophysics Data System (ADS)

Allen, M. R.; Rosier, S.; Massey, N.; Rye, C.; Bowery, A.; Miller, J.; Otto, F.; Jones, R.; Wilson, S.; Mote, P.; Stone, D. A.; Yamazaki, Y. H.; Carrington, D.

2011-12-01

Resolution and ensemble size are often seen as alternatives in climate modelling. Models with sufficient resolution to simulate many classes of extreme weather cannot normally be run often enough to assess the statistics of rare events, still less how these statistics may be changing. As a result, assessments of the impact of external forcing on regional climate extremes must be based either on statistical downscaling from relatively coarse-resolution models, or statistical extrapolation from 10-year to 100-year events. Under the weatherathome experiment, part of the climateprediction.net initiative, we have compiled the Met Office Regional Climate Model HadRM3P to run on personal computer volunteered by the general public at 25 and 50km resolution, embedded within the HadAM3P global atmosphere model. With a global network of about 50,000 volunteers, this allows us to run time-slice ensembles of essentially unlimited size, exploring the statistics of extreme weather under a range of scenarios for surface forcing and atmospheric composition, allowing for uncertainty in both boundary conditions and model parameters. Current experiments, developed with the support of Microsoft Research, focus on three regions, the Western USA, Europe and Southern Africa. We initially simulate the period 1959-2010 to establish which variables are realistically simulated by the model and on what scales. Our next experiments are focussing on the Event Attribution problem, exploring how the probability of various types of extreme weather would have been different over the recent past in a world unaffected by human influence, following the design of Pall et al (2011), but extended to a longer period and higher spatial resolution. We will present the first results of the unique, global, participatory experiment and discuss the implications for the attribution of recent weather events to anthropogenic influence on climate.

Translator for Optimizing Fluid-Handling Components

NASA Technical Reports Server (NTRS)

Landon, Mark; Perry, Ernest

2007-01-01

A software interface has been devised to facilitate optimization of the shapes of valves, elbows, fittings, and other components used to handle fluids under extreme conditions. This software interface translates data files generated by PLOT3D (a NASA grid-based plotting-and- data-display program) and by computational fluid dynamics (CFD) software into a format in which the files can be read by Sculptor, which is a shape-deformation- and-optimization program. Sculptor enables the user to interactively, smoothly, and arbitrarily deform the surfaces and volumes in two- and three-dimensional CFD models. Sculptor also includes design-optimization algorithms that can be used in conjunction with the arbitrary-shape-deformation components to perform automatic shape optimization. In the optimization process, the output of the CFD software is used as feedback while the optimizer strives to satisfy design criteria that could include, for example, improved values of pressure loss, velocity, flow quality, mass flow, etc.

A Projection of Changes in Landfilling Atmospheric River Frequency and Extreme Precipitation over Western North America from the Large Ensemble CESM Simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hagos, Samson M.; Leung, Lai-Yung R.; Yoon, Jin-Ho

Simulations from the Community Earth System Model Large Ensemble project are analyzed to investigate the impact of global warming on atmospheric rivers (ARs). The model has notable biases in simulating the subtropical jet position and the relationship between extreme precipitation and moisture transport. After accounting for these biases, the model projects an ensemble mean increase of 35% in the number of landfalling AR days between the last twenty years of the 20th and 21st centuries. However, the number of AR associated extreme precipitation days increases only by 28% because the moisture transport required to produce extreme precipitation also increases withmore » warming. Internal variability introduces an uncertainty of ±8% and ±7% in the projected changes in AR days and associated extreme precipitation days. In contrast, accountings for model biases only change the projected changes by about 1%. The significantly larger mean changes compared to internal variability and to the effects of model biases highlight the robustness of AR responses to global warming.« less

Evaluation in industry of a draft code of practice for manual handling.

PubMed

Ashby, Liz; Tappin, David; Bentley, Tim

2004-05-01

This paper reports findings from a study which evaluated the draft New Zealand Code of Practice for Manual Handling. The evaluation assessed the ease of use, applicability and validity of the Code and in particular the associated manual handling hazard assessment tools, within New Zealand industry. The Code was studied in a sample of eight companies from four sectors of industry. Subjective feedback and objective findings indicated that the Code was useful, applicable and informative. The manual handling hazard assessment tools incorporated in the Code could be adequately applied by most users, with risk assessment outcomes largely consistent with the findings of researchers using more specific ergonomics methodologies. However, some changes were recommended to the risk assessment tools to improve usability and validity. The evaluation concluded that both the Code and the tools within it would benefit from simplification, improved typography and layout, and industry-specific information on manual handling hazards.

Statistical downscaling modeling with quantile regression using lasso to estimate extreme rainfall

NASA Astrophysics Data System (ADS)

Santri, Dewi; Wigena, Aji Hamim; Djuraidah, Anik

2016-02-01

Rainfall is one of the climatic elements with high diversity and has many negative impacts especially extreme rainfall. Therefore, there are several methods that required to minimize the damage that may occur. So far, Global circulation models (GCM) are the best method to forecast global climate changes include extreme rainfall. Statistical downscaling (SD) is a technique to develop the relationship between GCM output as a global-scale independent variables and rainfall as a local- scale response variable. Using GCM method will have many difficulties when assessed against observations because GCM has high dimension and multicollinearity between the variables. The common method that used to handle this problem is principal components analysis (PCA) and partial least squares regression. The new method that can be used is lasso. Lasso has advantages in simultaneuosly controlling the variance of the fitted coefficients and performing automatic variable selection. Quantile regression is a method that can be used to detect extreme rainfall in dry and wet extreme. Objective of this study is modeling SD using quantile regression with lasso to predict extreme rainfall in Indramayu. The results showed that the estimation of extreme rainfall (extreme wet in January, February and December) in Indramayu could be predicted properly by the model at quantile 90th.

Have Large Dams Altered Extreme Precipitation Patterns?

NASA Astrophysics Data System (ADS)

Hossain, Faisal; Jeyachandran, Indumathi; Pielke, Roger

2009-12-01

Dams and their impounded waters are among the most common civil infrastructures, with a long heritage of modern design and operations experience. In particular, large dams, defined by the International Commission on Large Dams (ICOLD) as having a height greater than 15 meters from the foundation and holding a reservoir volume of more than 3 million cubic meters, have the potential to vastly transform local climate, landscapes, regional economics, and urbanization patterns. In the United States alone, about 75,000 dams are capable of storing a volume of water equaling almost 1 year's mean runoff of the nation [Graf, 1999]. The World Commission on Dams (WCD) reports that at least 45,000 large dams have been built worldwide since the 1930s. These sheer numbers raise the question of the extent to which large dams and their impounded waters alter patterns that would have been pervasive had the dams not been built.

Large Scale Influences on Summertime Extreme Precipitation in the Northeastern United States

NASA Technical Reports Server (NTRS)

Collow, Allison B. Marquardt; Bosilovich, Michael G.; Koster, Randal Dean

2016-01-01

Observations indicate that over the last few decades there has been a statistically significant increase in precipitation in the northeastern United States and that this can be attributed to an increase in precipitation associated with extreme precipitation events. Here a state-of-the-art atmospheric reanalysis is used to examine such events in detail. Daily extreme precipitation events defined at the 75th and 95th percentile from gridded gauge observations are identified for a selected region within the Northeast. Atmospheric variables from the Modern-Era Retrospective Analysis for Research and Applications, version 2 (MERRA-2), are then composited during these events to illustrate the time evolution of associated synoptic structures, with a focus on vertically integrated water vapor fluxes, sea level pressure, and 500-hectopascal heights. Anomalies of these fields move into the region from the northwest, with stronger anomalies present in the 95th percentile case. Although previous studies show tropical cyclones are responsible for the most intense extreme precipitation events, only 10 percent of the events in this study are caused by tropical cyclones. On the other hand, extreme events resulting from cutoff low pressure systems have increased. The time period of the study was divided in half to determine how the mean composite has changed over time. An arc of lower sea level pressure along the East Coast and a change in the vertical profile of equivalent potential temperature suggest a possible increase in the frequency or intensity of synoptic-scale baroclinic disturbances.

Dynamical systems proxies of atmospheric predictability and mid-latitude extremes

NASA Astrophysics Data System (ADS)

Messori, Gabriele; Faranda, Davide; Caballero, Rodrigo; Yiou, Pascal

2017-04-01

Extreme weather ocurrences carry enormous social and economic costs and routinely garner widespread scientific and media coverage. Many extremes (for e.g. storms, heatwaves, cold spells, heavy precipitation) are tied to specific patterns of midlatitude atmospheric circulation. The ability to identify these patterns and use them to enhance the predictability of the extremes is therefore a topic of crucial societal and economic value. We propose a novel predictability pathway for extreme events, by building upon recent advances in dynamical systems theory. We use two simple dynamical systems metrics - local dimension and persistence - to identify sets of similar large-scale atmospheric flow patterns which present a coherent temporal evolution. When these patterns correspond to weather extremes, they therefore afford a particularly good forward predictability. We specifically test this technique on European winter temperatures, whose variability largely depends on the atmospheric circulation in the North Atlantic region. We find that our dynamical systems approach provides predictability of large-scale temperature extremes up to one week in advance.

Extreme alien light allows survival of terrestrial bacteria

NASA Astrophysics Data System (ADS)

Johnson, Neil; Zhao, Guannan; Caycedo, Felipe; Manrique, Pedro; Qi, Hong; Rodriguez, Ferney; Quiroga, Luis

2013-07-01

Photosynthetic organisms provide a crucial coupling between the Sun's energy and metabolic processes supporting life on Earth. Searches for extraterrestrial life focus on seeking planets with similar incident light intensities and environments. However the impact of abnormal photon arrival times has not been considered. Here we present the counterintuitive result that broad classes of extreme alien light could support terrestrial bacterial life whereas sources more similar to our Sun might not. Our detailed microscopic model uses state-of-the-art empirical inputs including Atomic Force Microscopy (AFM) images. It predicts a highly nonlinear survivability for the basic lifeform Rsp. Photometricum whereby toxic photon feeds get converted into a benign metabolic energy supply by an interplay between the membrane's spatial structure and temporal excitation processes. More generally, our work suggests a new handle for manipulating terrestrial photosynthesis using currently-available extreme value statistics photon sources.

Physicochemical characterization of smoke aerosol during large-scale wildfires: Extreme event of August 2010 in Moscow

NASA Astrophysics Data System (ADS)

Popovicheva, O.; Kistler, M.; Kireeva, E.; Persiantseva, N.; Timofeev, M.; Kopeikin, V.; Kasper-Giebl, A.

2014-10-01

Enhancement of biomass burning-related research is essential for the assessment of large-scale wildfires impact on pollution at regional and global scale. Starting since 6 August 2010 Moscow was covered with thick smoke of unusually high PM10 and BC concentrations, considerably affected by huge forest and peat fires around megacity. This work presents the first comprehensive physico-chemical characterization of aerosols during extreme smoke event in Moscow in August 2010. Sampling was performed in the Moscow center and suburb as well as one year later, in August 2011 during a period when no biomass burning was observed. Small-scale experimental fires of regional biomass were conducted in the Moscow region. Carbon content, functionalities of organic/inorganic compounds, tracers of biomass burning (anhydrosaccharides), ionic composition, and structure of smoke were analyzed by thermal-optical analysis, FTIR spectroscopy, liquid and ion chromatography, and electron microscopy. Carbonaceous aerosol in August 2010 was dominated by organic species with elemental carbon (EC) as minor component. High average OC/EC near 27.4 is found, comparable to smoke of regional biomass smoldering fire, and exceeded 3 times the value observed in August 2011. Organic functionalities of Moscow smoke aerosols were hydroxyl, aliphatic, aromatic, acid and non-acid carbonyl, and nitro compound groups, almost all of them indicate wildfires around city as the source of smoke. The ratio of levoglucosan (LG) to mannosan near 5 confirms the origin of smoke from coniferous forest fires around megacity. Low ratio of LG/OC near 0.8% indicates the degradation of major molecular tracer of biomass burning in urban environment. Total concentration of inorganic ions dominated by sulfates SO4 2 - and ammonium NH4+ was found about 5 times higher during large-scale wildfires than in August 2011. Together with strong sulfate and ammonium absorbance in smoke aerosols, these observations prove the formation of

Students' Strategies for Exception Handling

ERIC Educational Resources Information Center

Rashkovits, Rami; Lavy, Ilana

2011-01-01

This study discusses and presents various strategies employed by novice programmers concerning exception handling. The main contributions of this paper are as follows: we provide an analysis tool to measure the level of assimilation of exception handling mechanism; we present and analyse strategies to handle exceptions; we present and analyse…

Large Scale Influences on Summertime Extreme Precipitation in the Northeastern United States.

PubMed

Marquardt Collow, Allison B; Bosilovich, Michael G; Koster, Randal D

2016-12-01

Observations indicate that over the last few decades there has been a statistically significant increase in precipitation in the Northeastern United States and that this can be attributed to an increase in precipitation associated with extreme precipitation events. Here we use a state-of-the-art atmospheric reanalysis to examine such events in detail. Daily extreme precipitation events defined at the 75 th and 95 th percentile from gridded gauge observations are identified for a selected region within the Northeast. Atmospheric variables from the Modern Era Retrospective Analysis for Research and Applications - Version 2 (MERRA-2) are then composited during these events to illustrate the time evolution of associated synoptic structures, with a focus on vertically integrated water vapor fluxes, sea level pressure, and 500 hPa heights. Anomalies of these fields move into the region from the northwest, with stronger anomalies present in the 95 th percentile case. Although previous studies show tropical cyclones are responsible for the most intense extreme precipitation events, only 10% of the events in this study are caused by tropical cyclones. On the other hand, extreme events resulting from cut off low pressure systems have increased. The time period of the study was divided in half to determine how the mean composite has changed over time. An arc of lower sea level pressure along the east coast and a change in the vertical profile of equivalent potential temperature suggest a possible increase in the frequency or intensity of synoptic scale baroclinic disturbances.

Microfluidics on liquid handling stations (μF-on-LHS): a new industry-compatible microfluidic platform

NASA Astrophysics Data System (ADS)

Kittelmann, Jörg; Radtke, Carsten P.; Waldbaur, Ansgar; Neumann, Christiane; Hubbuch, Jürgen; Rapp, Bastian E.

2014-03-01

Since the early days microfluidics as a scientific discipline has been an interdisciplinary research field with a wide scope of potential applications. Besides tailored assays for point-of-care (PoC) diagnostics, microfluidics has been an important tool for large-scale screening of reagents and building blocks in organic chemistry, pharmaceutics and medical engineering. Furthermore, numerous potential marketable products have been described over the years. However, especially in industrial applications, microfluidics is often considered only an alternative technology for fluid handling, a field which is industrially mostly dominated by large-scale numerically controlled fluid and liquid handling stations. Numerous noteworthy products have dominated this field in the last decade and have been inhibited the widespread application of microfluidics technology. However, automated liquid handling stations and microfluidics do not have to be considered as mutually exclusive approached. We have recently introduced a hybrid fluidic platform combining an industrially established liquid handling station and a generic microfluidic interfacing module that allows probing a microfluidic system (such as an essay or a synthesis array) using the instrumentation provided by the liquid handling station. We term this technology "Microfluidic on Liquid Handling Stations (μF-on-LHS)" - a classical "best of both worlds"- approach that allows combining the highly evolved, automated and industry-proven LHS systems with any type of microfluidic assay. In this paper we show, to the best of our knowledge, the first droplet microfluidics application on an industrial LHS using the μF-on-LHS concept.

Handle grip span for optimising finger-specific force capability as a function of hand size.

PubMed

Lee, Soo-Jin; Kong, Yong-Ku; Lowe, Brian D; Song, Seongho

2009-05-01

Five grip spans (45 to 65 mm) were tested to evaluate the effects of handle grip span and user's hand size on maximum grip strength, individual finger force and subjective ratings of comfort using a computerised digital dynamometer with independent finger force sensors. Forty-six males participated and were assigned into three hand size groups (small, medium, large) according to their hands' length. In general, results showed the 55- and 50-mm grip spans were rated as the most comfortable sizes and showed the largest grip strength (433.6 N and 430.8 N, respectively), whereas the 65-mm grip span handle was rated as the least comfortable size and the least grip strength. With regard to the interaction effect of grip span and hand size, small and medium-hand participants rated the best preference for the 50- to 55-mm grip spans and the least for the 65-mm grip span, whereas large-hand participants rated the 55- to 60-mm grip spans as the most preferred and the 45-mm grip span as the least preferred. Normalised grip span (NGS) ratios (29% and 27%) are the ratios of user's hand length to handle grip span. The NGS ratios were obtained and applied for suggesting handle grip spans in order to maximise subjective comfort as well as gripping force according to the users' hand sizes. In the analysis of individual finger force, the middle finger force showed the highest contribution (37.5%) to the total finger force, followed by the ring (28.7%), index (20.2%) and little (13.6%) finger. In addition, each finger was observed to have a different optimal grip span for exerting the maximum force, resulting in a bow-contoured shaped handle (the grip span of the handle at the centre is larger than the handle at the end) for two-handle hand tools. Thus, the grip spans for two-handle hand tools may be designed according to the users' hand/finger anthropometrics to maximise subjective ratings and performance based on this study. Results obtained in this study will provide guidelines

46 CFR 111.106-13 - Cargo handling devices or cargo pump rooms handling flammable or combustible cargoes.

Code of Federal Regulations, 2014 CFR

2014-10-01

... pierced by fixed lights, drive shafts, and pump-engine control rods, provided that the shafts and rods are... 46 Shipping 4 2014-10-01 2014-10-01 false Cargo handling devices or cargo pump rooms handling... OSVs § 111.106-13 Cargo handling devices or cargo pump rooms handling flammable or combustible cargoes...

Web-based visualization of very large scientific astronomy imagery

NASA Astrophysics Data System (ADS)

Bertin, E.; Pillay, R.; Marmo, C.

2015-04-01

Visualizing and navigating through large astronomy images from a remote location with current astronomy display tools can be a frustrating experience in terms of speed and ergonomics, especially on mobile devices. In this paper, we present a high performance, versatile and robust client-server system for remote visualization and analysis of extremely large scientific images. Applications of this work include survey image quality control, interactive data query and exploration, citizen science, as well as public outreach. The proposed software is entirely open source and is designed to be generic and applicable to a variety of datasets. It provides access to floating point data at terabyte scales, with the ability to precisely adjust image settings in real-time. The proposed clients are light-weight, platform-independent web applications built on standard HTML5 web technologies and compatible with both touch and mouse-based devices. We put the system to the test and assess the performance of the system and show that a single server can comfortably handle more than a hundred simultaneous users accessing full precision 32 bit astronomy data.

Rainfall extremes from TRMM data and the Metastatistical Extreme Value Distribution

NASA Astrophysics Data System (ADS)

Zorzetto, Enrico; Marani, Marco

2017-04-01

A reliable quantification of the probability of weather extremes occurrence is essential for designing resilient water infrastructures and hazard mitigation measures. However, it is increasingly clear that the presence of inter-annual climatic fluctuations determines a substantial long-term variability in the frequency of occurrence of extreme events. This circumstance questions the foundation of the traditional extreme value theory, hinged on stationary Poisson processes or on asymptotic assumptions to derive the Generalized Extreme Value (GEV) distribution. We illustrate here, with application to daily rainfall, a new approach to extreme value analysis, the Metastatistical Extreme Value Distribution (MEVD). The MEVD relaxes the above assumptions and is based on the whole distribution of daily rainfall events, thus allowing optimal use of all available observations. Using a global dataset of rain gauge observations, we show that the MEVD significantly outperforms the Generalized Extreme Value distribution, particularly for long average recurrence intervals and when small samples are available. The latter property suggests MEVD to be particularly suited for applications to satellite rainfall estimates, which only cover two decades, thus making extreme value estimation extremely challenging. Here we apply MEVD to the TRMM TMPA 3B42 product, an 18-year dataset of remotely-sensed daily rainfall providing a quasi-global coverage. Our analyses yield a global scale mapping of daily rainfall extremes and of their distributional tail properties, bridging the existing large gaps in ground-based networks. Finally, we illustrate how our global-scale analysis can provide insight into how properties of local rainfall regimes affect tail estimation uncertainty when using the GEV or MEVD approach. We find a dependence of the estimation uncertainty, for both the GEV- and MEV-based approaches, on the average annual number and on the inter-annual variability of rainy days. In

Development of liquid handling techniques in microgravity

NASA Technical Reports Server (NTRS)

Antar, Basil N.

1995-01-01

A large number of experiments dealing with protein crystal growth and also with growth of crystals from solution require complicated fluid handling procedures including filling of empty containers with liquids, mixing of solutions, and stirring of liquids. Such procedures are accomplished in a straight forward manner when performed under terrestrial conditions in the laboratory. However, in the low gravity environment of space, such as on board the Space Shuttle or an Earth-orbiting space station, these procedures sometimes produced entirely undesirable results. Under terrestrial conditions, liquids usually completely separate from the gas due to the buoyancy effects of Earth's gravity. Consequently, any gas pockets that are entrained into the liquid during a fluid handling procedure will eventually migrate towards the top of the vessel where they can be removed. In a low gravity environment any folded gas bubble will remain within the liquid bulk indefinitely at a location that is not known a priori resulting in a mixture of liquid and vapor.

Abnormal MRI in a patient with 'headache with neurological deficits and CSF lymphocytosis (HaNDL)'.

PubMed

Yilmaz, A; Kaleagasi, H; Dogu, O; Kara, E; Ozge, A

2010-05-01

A 27-year-old woman was admitted to the Emergency Department with right upper-extremity numbness and mild weakness followed by a bifrontal throbbing headache for 30 min, which was similar to a headache lasting for 12 h that had occurred 3 days ago. Laboratory tests were unremarkable except for cerebrospinal fluid (CSF) lymphocytic pleocytosis. On the following day, a headache episode with left hemiparesis and hemihypoaesthesia, left hemifield visio-spatial inattention, anosagnosia and confusion recurred. The headache was diagnosed as headache and neurological deficits with cerebrospinal fluid lymphocytosis (HaNDL) syndrome according to the criteria of the second edition of the International Classification of Headache Disorders. Simultaneously performed magnetic resonance imaging (MRI) revealed swelling of the grey matter, CSF enhancement in the sulci of the right temporal and occipital regions and hypoperfusion of the same brain regions. During the following 10 days two more similar episodes recurred and during the ensuing 12 months the patient remained headache free. Neuroimaging findings of the HaNDL syndrome are always thought as virtually normal. MRI abnormalities in our patient have not been reported in HaNDL syndrome previously, although they have been reported in hemiplegic migraine patients before. The findings in our case suggest that hemiplegic migraine and HaNDL syndrome may share a common pathophysiological pathway resulting in similar imaging findings and neurological symptoms.

A dynamical systems approach to studying midlatitude weather extremes

NASA Astrophysics Data System (ADS)

Messori, Gabriele; Caballero, Rodrigo; Faranda, Davide

2017-04-01

Extreme weather occurrences carry enormous social and economic costs and routinely garner widespread scientific and media coverage. The ability to predict these events is therefore a topic of crucial importance. Here we propose a novel predictability pathway for extreme events, by building upon recent advances in dynamical systems theory. We show that simple dynamical systems metrics can be used to identify sets of large-scale atmospheric flow patterns with similar spatial structure and temporal evolution on time scales of several days to a week. In regions where these patterns favor extreme weather, they afford a particularly good predictability of the extremes. We specifically test this technique on the atmospheric circulation in the North Atlantic region, where it provides predictability of large-scale wintertime surface temperature extremes in Europe up to 1 week in advance.

Static tool influence function for fabrication simulation of hexagonal mirror segments for extremely large telescopes.

PubMed

Kim, Dae Wook; Kim, Sug-Whan

2005-02-07

We present a novel simulation technique that offers efficient mass fabrication strategies for 2m class hexagonal mirror segments of extremely large telescopes. As the first of two studies in series, we establish the theoretical basis of the tool influence function (TIF) for precessing tool polishing simulation for non-rotating workpieces. These theoretical TIFs were then used to confirm the reproducibility of the material removal foot-prints (measured TIFs) of the bulged precessing tooling reported elsewhere. This is followed by the reverse-computation technique that traces, employing the simplex search method, the real polishing pressure from the empirical TIF. The technical details, together with the results and implications described here, provide the theoretical tool for material removal essential to the successful polishing simulation which will be reported in the second study.

Handling Missing Data With Multilevel Structural Equation Modeling and Full Information Maximum Likelihood Techniques.

PubMed

Schminkey, Donna L; von Oertzen, Timo; Bullock, Linda

2016-08-01

With increasing access to population-based data and electronic health records for secondary analysis, missing data are common. In the social and behavioral sciences, missing data frequently are handled with multiple imputation methods or full information maximum likelihood (FIML) techniques, but healthcare researchers have not embraced these methodologies to the same extent and more often use either traditional imputation techniques or complete case analysis, which can compromise power and introduce unintended bias. This article is a review of options for handling missing data, concluding with a case study demonstrating the utility of multilevel structural equation modeling using full information maximum likelihood (MSEM with FIML) to handle large amounts of missing data. MSEM with FIML is a parsimonious and hypothesis-driven strategy to cope with large amounts of missing data without compromising power or introducing bias. This technique is relevant for nurse researchers faced with ever-increasing amounts of electronic data and decreasing research budgets. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Musculoskeletal injuries resulting from patient handling tasks among hospital workers.

PubMed

Pompeii, Lisa A; Lipscomb, Hester J; Schoenfisch, Ashley L; Dement, John M

2009-07-01

The purpose of this study was to evaluate musculoskeletal injuries and disorders resulting from patient handling prior to the implementation of a "minimal manual lift" policy at a large tertiary care medical center. We sought to define the circumstances surrounding patient handling injuries and to identify potential preventive measures. Human resources data were used to define the cohort and their time at work. Workers' compensation records (1997-2003) were utilized to identify work-related musculoskeletal claims, while the workers' description of injury was used to identify those that resulted from patient handling. Adjusted rate ratios were generated using Poisson regression. One-third (n = 876) of all musculoskeletal injuries resulted from patient handling activities. Most (83%) of the injury burden was incurred by inpatient nurses, nurses' aides and radiology technicians, while injury rates were highest for nurses' aides (8.8/100 full-time equivalent, FTEs) and smaller workgroups including emergency medical technicians (10.3/100 FTEs), patient transporters (4.3/100 FTEs), operating room technicians (3.1/100 FTEs), and morgue technicians (2.2/100 FTEs). Forty percent of injuries due to lifting/transferring patients may have been prevented through the use of mechanical lift equipment, while 32% of injuries resulting from repositioning/turning patients, pulling patients up in bed, or catching falling patients may not have been prevented by the use of lift equipment. The use of mechanical lift equipment could significantly reduce the risk of some patient handling injuries but additional interventions need to be considered that address other patient handling tasks. Smaller high-risk workgroups should not be neglected in prevention efforts.

Large-scale Agroecosytem's Resiliency to Extreme Hydrometeorological and Climate Extreme Events in the Missouri River Basin

NASA Astrophysics Data System (ADS)

Munoz-Arriola, F.; Smith, K.; Corzo, G.; Chacon, J.; Carrillo-Cruz, C.

2015-12-01

A major challenge for water, energy and food security relies on the capability of agroecosyststems and ecosystems to adapt to a changing climate and land use changes. The interdependency of these forcings, understood through our ability to monitor and model processes across scales, indicate the "depth" of their impact on agroecosystems and ecosystems, and consequently our ability to predict the system's ability to return to a "normal" state. We are particularly interested in explore two questions: (1) how hydrometeorological and climate extreme events (HCEs) affect sub-seasonal to interannual changes in evapotranspiration and soil moisture? And (2) how agroecosystems recover from the effect of such events. To address those questions we use the land surface hydrologic Variable Infiltration Capacity (VIC) model and the Moderate Resolution Imaging Spectrometer-Leaf Area Index (MODIS-LAI) over two time spans (1950-2013 using a seasonal fixed LAI cycle) and 2001-2013 (an 8-day MODIS-LAI). VIC is forced by daily/16th degree resolution precipitation, minimum and maximum temperature, and wind speed. In this large-scale experiment, resiliency is defined by the capacity of a particular agroecosystem, represented by a grid cell's ET, SM, and LAI to return to a historical average. This broad, yet simplistic definition will contribute to identify the possible components and their scales involved in agroecosystems and ecosystems capacity to adapt to the incidence of HCEs and technologies used to intensify agriculture and diversify their use for food and energy production. Preliminary results show that dynamical changes in land use, tracked by MODIS data, require larger time spans to address properly the influence of technologic improvements in crop production as well as the competition for land for biofuel vs. food production. On the other hand, fixed seasonal changes in land use allow us just to identify hydrologic changes mainly due to climate variability.

Helicopter Handling Qualities

NASA Technical Reports Server (NTRS)

1982-01-01

Helicopters are used by the military and civilian communities for a variety of tasks and must be capable of operating in poor weather conditions and at night. Accompanying extended helicopter operations is a significant increase in pilot workload and a need for better handling qualities. An overview of the status and problems in the development and specification of helicopter handling-qualities criteria is presented. Topics for future research efforts by government and industry are highlighted.

Analysis of Extreme Star Formation Environments in the Large Magellanic Cloud

NASA Astrophysics Data System (ADS)

Nayak, Omnarayani

2018-01-01

My thesis is on three extreme star forming environments in the Large Magellanic Cloud: 30 Doradus, N159, and N79. These three regions are at different evolutionary stage of forming stars. N79 is at a very young stage, just starting its star formation activity. N159 is currently actively forming several massive YSOs. And 30 Doradus has already passed it peak star formation, and several protostars are no longer shrouded by gas and dust, and are starting to be more visible in the optical wavelengths. I analyze the CO molecular gas clouds with ALMA in 30 Doradus, N159, and N79. I identify all massive YSOs within the ALMA footprint of all three regions. My thesis is on relating the star formation activity in 30 Doradus, N159, and N79 to the high density gas in which these protostars form. I find that not all massive young stellar objects are associated with CO gas, higher mass clumps tend to form higher mass stars, and lower mass clumps tend to not be gravitationally bound however the larger clouds are bound. I use ancillary SOFIA data and Magellan FIRE data to place constraints on the outflow rate from the massive protostars, constrain the temperature of the gas, determine the spectral type of the young stellar objects, and estimate the extinction. Looking at the interplay between dense molecular gas and the newly forming stars in a stellar nursery will shed light on how these stars formed: filamentary collision, monolithic collapse, or competitive accretion. The Large Magellanic Cloud has been the subject of star formation studies for decades due to its proximity to the Milky Way (50 kpc), a nearly face-on orientation, and a low metallicity (0.5 solar) similar to that of galaxies at the peak of star formation in the universe (z~2). Thus, my thesis probes the chemical and physical conditions necessary for massive star formation in an environment more typical of the peak of star formation in the universe.

Measurement of doses to the extremities of nuclear medicine staff

NASA Astrophysics Data System (ADS)

Shousha, Hany A.; Farag, Hamed; Hassan, Ramadan A.

2010-01-01

Medical uses of ionizing radiation now represent>95% of all man-made radiation exposure, and is the largest single radiation source after natural background radiation. Therefore, it is important to quantify the amount of radiation received by occupational individuals to optimize the working conditions for staff, and further, to compare doses in different departments to ensure compatibility with the recommended standards. For some groups working with unsealed sources in nuclear medicine units, the hands are more heavily exposed to ionizing radiation than the rest of the body. A personal dosimetry service runs extensively in Egypt. But doses to extremities have not been measured to a wide extent. The purpose of this study was to investigate the equivalent radiation doses to the fingers for five different nuclear medicine staff occupational groups for which heavy irradiation of the hands was suspected. Finger doses were measured for (1) nuclear medicine physicians, (2) technologists, (3) nurses and (4) physicists. The fifth group contains three technicians handling 131I, while the others handled 99mTc. Each staff member working with the radioactive material wore two thermoluminescent dosimeters (TLDs) during the whole testing period, which lasted from 1 to 4 weeks. Staff performed their work on a regular basis throughout the month, and mean annual doses were calculated for these groups. Results showed that the mean equivalent doses to the fingers of technologist, nurse and physicist groups were 30.24±14.5, 30.37±17.5 and 16.3±7.7 μSv/GBq, respectively. Equivalent doses for the physicians could not be calculated per unit of activity because they did not handle the radiopharmaceuticals directly. Their doses were reported in millisieverts (mSv) that accumulated in one week. Similarly, the dose to the fingers of individuals in Group 5 was estimated to be 126.13±38.2 μSv/GBq. The maximum average finger dose, in this study, was noted in the technologists who handled

Ergonomics and patient handling.

PubMed

McCoskey, Kelsey L

2007-11-01

This study aimed to describe patient-handling demands in inpatient units during a 24-hour period at a military health care facility. A 1-day total population survey described the diverse nature and impact of patient-handling tasks relative to a variety of nursing care units, patient characteristics, and transfer equipment. Productivity baselines were established based on patient dependency, physical exertion, type of transfer, and time spent performing the transfer. Descriptions of the physiological effect of transfers on staff based on patient, transfer, and staff characteristics were developed. Nursing staff response to surveys demonstrated how patient-handling demands are impacted by the staff's physical exertion and level of patient dependency. The findings of this study describe the types of transfers occurring in these inpatient units and the physical exertion and time requirements for these transfers. This description may guide selection of the most appropriate and cost-effective patient-handling equipment required for specific units and patients.

Generalized extreme gust wind speeds distributions

USGS Publications Warehouse

Cheng, E.; Yeung, C.

2002-01-01

Since summer 1996, the US wind engineers are using the extreme gust (or 3-s gust) as the basic wind speed to quantify the destruction of extreme winds. In order to better understand these destructive wind forces, it is important to know the appropriate representations of these extreme gust wind speeds. Therefore, the purpose of this study is to determine the most suitable extreme value distributions for the annual extreme gust wind speeds recorded in large selected areas. To achieve this objective, we are using the generalized Pareto distribution as the diagnostic tool for determining the types of extreme gust wind speed distributions. The three-parameter generalized extreme value distribution function is, thus, reduced to either Type I Gumbel, Type II Frechet or Type III reverse Weibull distribution function for the annual extreme gust wind speeds recorded at a specific site.With the considerations of the quality and homogeneity of gust wind data collected at more than 750 weather stations throughout the United States, annual extreme gust wind speeds at selected 143 stations in the contiguous United States were used in the study. ?? 2002 Elsevier Science Ltd. All rights reserved.

Reaction factoring and bipartite update graphs accelerate the Gillespie Algorithm for large-scale biochemical systems.

PubMed

Indurkhya, Sagar; Beal, Jacob

2010-01-06

ODE simulations of chemical systems perform poorly when some of the species have extremely low concentrations. Stochastic simulation methods, which can handle this case, have been impractical for large systems due to computational complexity. We observe, however, that when modeling complex biological systems: (1) a small number of reactions tend to occur a disproportionately large percentage of the time, and (2) a small number of species tend to participate in a disproportionately large percentage of reactions. We exploit these properties in LOLCAT Method, a new implementation of the Gillespie Algorithm. First, factoring reaction propensities allows many propensities dependent on a single species to be updated in a single operation. Second, representing dependencies between reactions with a bipartite graph of reactions and species requires only storage for reactions, rather than the required for a graph that includes only reactions. Together, these improvements allow our implementation of LOLCAT Method to execute orders of magnitude faster than currently existing Gillespie Algorithm variants when simulating several yeast MAPK cascade models.

A Fast SVD-Hidden-nodes based Extreme Learning Machine for Large-Scale Data Analytics.

PubMed

Deng, Wan-Yu; Bai, Zuo; Huang, Guang-Bin; Zheng, Qing-Hua

2016-05-01

Big dimensional data is a growing trend that is emerging in many real world contexts, extending from web mining, gene expression analysis, protein-protein interaction to high-frequency financial data. Nowadays, there is a growing consensus that the increasing dimensionality poses impeding effects on the performances of classifiers, which is termed as the "peaking phenomenon" in the field of machine intelligence. To address the issue, dimensionality reduction is commonly employed as a preprocessing step on the Big dimensional data before building the classifiers. In this paper, we propose an Extreme Learning Machine (ELM) approach for large-scale data analytic. In contrast to existing approaches, we embed hidden nodes that are designed using singular value decomposition (SVD) into the classical ELM. These SVD nodes in the hidden layer are shown to capture the underlying characteristics of the Big dimensional data well, exhibiting excellent generalization performances. The drawback of using SVD on the entire dataset, however, is the high computational complexity involved. To address this, a fast divide and conquer approximation scheme is introduced to maintain computational tractability on high volume data. The resultant algorithm proposed is labeled here as Fast Singular Value Decomposition-Hidden-nodes based Extreme Learning Machine or FSVD-H-ELM in short. In FSVD-H-ELM, instead of identifying the SVD hidden nodes directly from the entire dataset, SVD hidden nodes are derived from multiple random subsets of data sampled from the original dataset. Comprehensive experiments and comparisons are conducted to assess the FSVD-H-ELM against other state-of-the-art algorithms. The results obtained demonstrated the superior generalization performance and efficiency of the FSVD-H-ELM. Copyright © 2016 Elsevier Ltd. All rights reserved.

Extremely large nonsaturating magnetoresistance and ultrahigh mobility due to topological surface states in the metallic Bi2Te3 topological insulator

NASA Astrophysics Data System (ADS)

Shrestha, K.; Chou, M.; Graf, D.; Yang, H. D.; Lorenz, B.; Chu, C. W.

2017-05-01

Weak antilocalization (WAL) effects in Bi2Te3 single crystals have been investigated at high and low bulk charge-carrier concentrations. At low charge-carrier density the WAL curves scale with the normal component of the magnetic field, demonstrating the dominance of topological surface states in magnetoconductivity. At high charge-carrier density the WAL curves scale with neither the applied field nor its normal component, implying a mixture of bulk and surface conduction. WAL due to topological surface states shows no dependence on the nature (electrons or holes) of the bulk charge carriers. The observations of an extremely large nonsaturating magnetoresistance and ultrahigh mobility in the samples with lower carrier density further support the presence of surface states. The physical parameters characterizing the WAL effects are calculated using the Hikami-Larkin-Nagaoka formula. At high charge-carrier concentrations, there is a greater number of conduction channels and a decrease in the phase coherence length compared to low charge-carrier concentrations. The extremely large magnetoresistance and high mobility of topological insulators have great technological value and can be exploited in magnetoelectric sensors and memory devices.

Complaint handling in healthcare: expectation gaps between physicians and the public; results of a survey study.

PubMed

Friele, R D; Reitsma, P M; de Jong, J D

2015-10-01

Patients who submit complaints about the healthcare they have received are often dissatisfied with the response to their complaints. This is usually attributed to the failure of physicians to respond adequately to what complainants want, e.g. an apology or an explanation. However, expectations of complaint handling among the public may colour how they evaluate the way their own complaint is handled. This descriptive study assesses expectations of complaint handling in healthcare among the public and physicians. Negative public expectations and the gap between these expectations and those of physicians may explain patients' dissatisfaction with complaints procedures. We held two surveys; one among physicians, using a panel of 3366 physicians (response rate 57 %, containing all kinds of physicians like GP's, medical specialist and physicians working in a nursing home) and one among the public, using the Dutch Healthcare Consumer Panel (n = 1422, response rate 68 %). We asked both panels identical questions about their expectations of how complaints are handled in healthcare. Differences in expectation scores between the public and the physicians were tested using non-parametric tests. The public have negative expectations about how complaints are handled. Physician's expectations are far more positive, demonstrating large expectation gaps between physicians and the public. The large expectation gap between the public and physicians means that when they meet because of complaint, they are likely to start off with opposite expectations of the situation. This is no favourable condition for a positive outcome of a complaints procedure. The negative public preconceptions about the way their complaint will be handled will prove hard to change during the process of complaints handling. People tend to see what they thought would happen, almost inevitably leading to a negative judgement about how their complaint was handled.

Decreasing spatial variability in precipitation extremes in southwestern China and the local/large-scale influencing factors

NASA Astrophysics Data System (ADS)

Liu, Meixian; Xu, Xianli; Sun, Alex

2015-07-01

Climate extremes can cause devastating damage to human society and ecosystems. Recent studies have drawn many conclusions about trends in climate extremes, but few have focused on quantitative analysis of their spatial variability and underlying mechanisms. By using the techniques of overlapping moving windows, the Mann-Kendall trend test, correlation, and stepwise regression, this study examined the spatial-temporal variation of precipitation extremes and investigated the potential key factors influencing this variation in southwestern (SW) China, a globally important biodiversity hot spot and climate-sensitive region. Results showed that the changing trends of precipitation extremes were not spatially uniform, but the spatial variability of these precipitation extremes decreased from 1959 to 2012. Further analysis found that atmospheric circulations rather than local factors (land cover, topographic conditions, etc.) were the main cause of such precipitation extremes. This study suggests that droughts or floods may become more homogenously widespread throughout SW China. Hence, region-wide assessments and coordination are needed to help mitigate the economic and ecological impacts.

7 CFR 1210.307 - Handle.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE WATERMELON RESEARCH AND PROMOTION PLAN Watermelon Research and Promotion Plan Definitions § 1210.307 Handle. Handle means to grade, pack...

7 CFR 1210.307 - Handle.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE WATERMELON RESEARCH AND PROMOTION PLAN Watermelon Research and Promotion Plan Definitions § 1210.307 Handle. Handle means to grade, pack...

7 CFR 1210.307 - Handle.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE WATERMELON RESEARCH AND PROMOTION PLAN Watermelon Research and Promotion Plan Definitions § 1210.307 Handle. Handle means to grade, pack...

7 CFR 1210.307 - Handle.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE WATERMELON RESEARCH AND PROMOTION PLAN Watermelon Research and Promotion Plan Definitions § 1210.307 Handle. Handle means to grade, pack...

Extremely large magnetoresistance in the topologically trivial semimetal α -WP2

NASA Astrophysics Data System (ADS)

Du, Jianhua; Lou, Zhefeng; Zhang, ShengNan; Zhou, Yuxing; Xu, Binjie; Chen, Qin; Tang, Yanqing; Chen, Shuijin; Chen, Huancheng; Zhu, Qinqing; Wang, Hangdong; Yang, Jinhu; Wu, QuanSheng; Yazyev, Oleg V.; Fang, Minghu

2018-06-01

Extremely large magnetoresistance (XMR) was recently discovered in many nonmagnetic materials, while its underlying mechanism remains poorly understood due to the complex electronic structure of these materials. Here we report an investigation of the α -phase WP2, a topologically trivial semimetal with monoclinic crystal structure (C 2 /m ), which contrasts with the recently discovered robust type-II Weyl semimetal phase in β -WP2 . We found that α -WP2 exhibits almost all the characteristics of XMR materials: the near-quadratic field dependence of MR, a field-induced up-turn in resistivity followed by a plateau at low temperature, which can be understood by the compensation effect, and high mobility of carriers confirmed by our Hall effect measurements. It was also found that the normalized MRs under different magnetic fields have the same temperature dependence in α -WP2 , the Kohler scaling law can describe the MR data in a wide temperature range, and there is no obvious change in the anisotropic parameter γ value with temperature. The resistance polar diagram has a peanut shape when the field is rotated in the a c plane, which can be understood by the anisotropy of the Fermi surface. These results indicate that both field-induced-gap and temperature-induced Lifshitz transition are not the origin of up-turn in resistivity in the α -WP2 semimetal. Our findings establish α -WP2 as a new reference material for exploring the XMR phenomena.

Grain Handling and Storage.

ERIC Educational Resources Information Center

Harris, Troy G.; Minor, John

This text for a secondary- or postecondary-level course in grain handling and storage contains ten chapters. Chapter titles are (1) Introduction to Grain Handling and Storage, (2) Elevator Safety, (3) Grain Grading and Seed Identification, (4) Moisture Control, (5) Insect and Rodent Control, (6) Grain Inventory Control, (7) Elevator Maintenance,…

Real-time turbulence profiling with a pair of laser guide star Shack-Hartmann wavefront sensors for wide-field adaptive optics systems on large to extremely large telescopes.

PubMed

Gilles, L; Ellerbroek, B L

2010-11-01

Real-time turbulence profiling is necessary to tune tomographic wavefront reconstruction algorithms for wide-field adaptive optics (AO) systems on large to extremely large telescopes, and to perform a variety of image post-processing tasks involving point-spread function reconstruction. This paper describes a computationally efficient and accurate numerical technique inspired by the slope detection and ranging (SLODAR) method to perform this task in real time from properly selected Shack-Hartmann wavefront sensor measurements accumulated over a few hundred frames from a pair of laser guide stars, thus eliminating the need for an additional instrument. The algorithm is introduced, followed by a theoretical influence function analysis illustrating its impulse response to high-resolution turbulence profiles. Finally, its performance is assessed in the context of the Thirty Meter Telescope multi-conjugate adaptive optics system via end-to-end wave optics Monte Carlo simulations.

EUVL mask dual pods to be used for mask shipping and handling in exposure tools

NASA Astrophysics Data System (ADS)

Gomei, Yoshio; Ota, Kazuya; Lystad, John; Halbmair, Dave; He, Long

2007-03-01

The concept of Extreme Ultra-Violet Lithography (EUVL) mask dual pods is proposed for use in both mask shipping and handling in exposure tools. The inner pod was specially designed to protect masks from particle contamination during shipping from mask houses to wafer factories. It can be installed in a load-lock chamber of exposure tools and evacuated while holding the mask inside. The inner pod upper cover is removed just before the mask is installed to a mask stage. Prototypes were manufactured and tested for shipping and for vacuum cycling. We counted particle adders through these actions with a detectable level of 54 nm and up. The adder count was close to zero, or we can say that the obtained result is within the noise level of our present evaluation environment. This indicates that the present concept is highly feasible for EUVL mask shipping and handling in exposure tools.

New Surgical Drapes for Observation of the Lower Extremities during Abdominal Aortic Repair.

PubMed

Obitsu, Yukio; Shigematsu, Hiroshi; Satou, Kazuhiro; Watanabe, Yoshiko; Saiki, Naozumi; Koizumii, Nobusato

2010-01-01

For the early diagnosis and therapy of peripheral thromboembolism (TE) as a complication of abdominal aortic repair (AAR), we developed and evaluated the usefulness of surgical drapes that permit observation of the lower extremities during AAR. Between January 2007 and June 2009, the handling, durability, and usefulness of new surgical drapes were evaluated during AAR in 157 patients with abdominal aortic aneurysms and 9 patients with peripheral arterial disease. The drapes are manufactured by Hogy Medical Co. Ltd. and made of a water-repellent, spun lace, non-woven fabric, including a transparent polyethylene film that covers the patients' legs. This transparent film enables inspection and palpation of the lower extremities during surgery for early diagnosis and therapy of peripheral TE. As a peripheral complication, 1 patient had right lower extremity TE. This was diagnosed immediately after anastomosis, thrombectomy was performed, and the remaining clinical course was uneventful. In all patients, the drapes permitted observation of the lower extremities , and the dorsal arteries were palpable. There were no problems with durability. New surgical drapes permit observation of the lower extremities during AAR for early diagnosis and treatment of peripheral TE.

Climate impacts on extreme energy consumption of different types of buildings.

PubMed

Li, Mingcai; Shi, Jun; Guo, Jun; Cao, Jingfu; Niu, Jide; Xiong, Mingming

2015-01-01

Exploring changes of building energy consumption and its relationships with climate can provide basis for energy-saving and carbon emission reduction. Heating and cooling energy consumption of different types of buildings during 1981-2010 in Tianjin city, was simulated by using TRNSYS software. Daily or hourly extreme energy consumption was determined by percentile methods, and the climate impact on extreme energy consumption was analyzed. The results showed that days of extreme heating consumption showed apparent decrease during the recent 30 years for residential and large venue buildings, whereas days of extreme cooling consumption increased in large venue building. No significant variations were found for the days of extreme energy consumption for commercial building, although a decreasing trend in extreme heating energy consumption. Daily extreme energy consumption for large venue building had no relationship with climate parameters, whereas extreme energy consumption for commercial and residential buildings was related to various climate parameters. Further multiple regression analysis suggested heating energy consumption for commercial building was affected by maximum temperature, dry bulb temperature, solar radiation and minimum temperature, which together can explain 71.5 % of the variation of the daily extreme heating energy consumption. The daily extreme cooling energy consumption for commercial building was only related to the wet bulb temperature (R2= 0.382). The daily extreme heating energy consumption for residential building was affected by 4 climate parameters, but the dry bulb temperature had the main impact. The impacts of climate on hourly extreme heating energy consumption has a 1-3 hour delay in all three types of buildings, but no delay was found in the impacts of climate on hourly extreme cooling energy consumption for the selected buildings.

How extreme are extremes?

NASA Astrophysics Data System (ADS)

Cucchi, Marco; Petitta, Marcello; Calmanti, Sandro

2016-04-01

High temperatures have an impact on the energy balance of any living organism and on the operational capabilities of critical infrastructures. Heat-wave indicators have been mainly developed with the aim of capturing the potential impacts on specific sectors (agriculture, health, wildfires, transport, power generation and distribution). However, the ability to capture the occurrence of extreme temperature events is an essential property of a multi-hazard extreme climate indicator. Aim of this study is to develop a standardized heat-wave indicator, that can be combined with other indices in order to describe multiple hazards in a single indicator. The proposed approach can be used in order to have a quantified indicator of the strenght of a certain extreme. As a matter of fact, extremes are usually distributed in exponential or exponential-exponential functions and it is difficult to quickly asses how strong was an extreme events considering only its magnitude. The proposed approach simplify the quantitative and qualitative communication of extreme magnitude

7 CFR 905.9 - Handle or ship.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 8 2011-01-01 2011-01-01 false Handle or ship. 905.9 Section 905.9 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... TANGELOS GROWN IN FLORIDA Order Regulating Handling Definitions § 905.9 Handle or ship. Handle or ship...

7 CFR 948.8 - Handle or ship.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 8 2011-01-01 2011-01-01 false Handle or ship. 948.8 Section 948.8 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Order Regulating Handling Definitions § 948.8 Handle or ship. Handle or ship means to transport, sell...

7 CFR 905.9 - Handle or ship.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 8 2014-01-01 2014-01-01 false Handle or ship. 905.9 Section 905.9 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... TANGELOS GROWN IN FLORIDA Order Regulating Handling Definitions § 905.9 Handle or ship. Handle or ship...

7 CFR 905.9 - Handle or ship.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 8 2012-01-01 2012-01-01 false Handle or ship. 905.9 Section 905.9 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... TANGELOS GROWN IN FLORIDA Order Regulating Handling Definitions § 905.9 Handle or ship. Handle or ship...

7 CFR 948.8 - Handle or ship.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 8 2013-01-01 2013-01-01 false Handle or ship. 948.8 Section 948.8 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Order Regulating Handling Definitions § 948.8 Handle or ship. Handle or ship means to transport, sell...

7 CFR 905.9 - Handle or ship.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 8 2013-01-01 2013-01-01 false Handle or ship. 905.9 Section 905.9 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... TANGELOS GROWN IN FLORIDA Order Regulating Handling Definitions § 905.9 Handle or ship. Handle or ship...

7 CFR 948.8 - Handle or ship.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 8 2014-01-01 2014-01-01 false Handle or ship. 948.8 Section 948.8 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Order Regulating Handling Definitions § 948.8 Handle or ship. Handle or ship means to transport, sell...

7 CFR 948.8 - Handle or ship.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 8 2012-01-01 2012-01-01 false Handle or ship. 948.8 Section 948.8 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Order Regulating Handling Definitions § 948.8 Handle or ship. Handle or ship means to transport, sell...

FUEL HANDLING MECHANISM

DOEpatents

Koch, L.J.; Hutter, E.

1960-02-01

A remotely operable handling device specifically adapted for the handling of vertically disposed fuel rods in a nuclear reactor was developed. The device consists essentially of an elongated tubular member having a gripping device at the lower end of the pivoted jaw type adapted to grip an enlarged head on the upper end of the workpiece. The device includes a sensing element which engages the enlarged head and is displaced to remotely indicate when the workpiece is in the proper position to be engaged by the jaws.

Early studies reported extreme findings with large variability: a meta-epidemiologic study in the field of endocrinology.

PubMed

Wang, Zhen; Alahdab, Fares; Almasri, Jehad; Haydour, Qusay; Mohammed, Khaled; Abu Dabrh, Abd Moain; Prokop, Larry J; Alfarkh, Wedad; Lakis, Sumaya; Montori, Victor M; Murad, Mohammad Hassan

2016-04-01

To evaluate the presence of extreme findings and fluctuation in effect size in endocrinology. We systematically identified all meta-analyses published in 2014 in the field of endocrinology. Within each meta-analysis, the effect size of the primary binary outcome was compared across studies according to their order of publication. We pooled studies using the DerSimonian and Laird random-effects method. Heterogeneity was evaluated using the I(2) and tau(2). Twelve percent of the included 100 meta-analyses reported the largest effect size in the very first published study. The largest effect size occurred in the first 2 earliest studies in 31% of meta-analyses. When the effect size was the largest in the first published study, it was three times larger than the final pooled effect (ratio of rates, 3.26; 95% confidence interval: 1.80, 5.90). The largest heterogeneity measured by I(2) was observed in 18% of the included meta-analyses when combining the first 2 studies or 17% when combing the first 3 studies. In endocrinology, early studies reported extreme findings with large variability. This behavior of the evidence needs to be taken into account when used to formulate clinical policies. Copyright © 2016 Elsevier Inc. All rights reserved.

Polygenic determinants in extremes of high-density lipoprotein cholesterol.

PubMed

Dron, Jacqueline S; Wang, Jian; Low-Kam, Cécile; Khetarpal, Sumeet A; Robinson, John F; McIntyre, Adam D; Ban, Matthew R; Cao, Henian; Rhainds, David; Dubé, Marie-Pierre; Rader, Daniel J; Lettre, Guillaume; Tardif, Jean-Claude; Hegele, Robert A

2017-11-01

HDL cholesterol (HDL-C) remains a superior biochemical predictor of CVD risk, but its genetic basis is incompletely defined. In patients with extreme HDL-C concentrations, we concurrently evaluated the contributions of multiple large- and small-effect genetic variants. In a discovery cohort of 255 unrelated lipid clinic patients with extreme HDL-C levels, we used a targeted next-generation sequencing panel to evaluate rare variants in known HDL metabolism genes, simultaneously with common variants bundled into a polygenic trait score. Two additional cohorts were used for validation and included 1,746 individuals from the Montréal Heart Institute Biobank and 1,048 individuals from the University of Pennsylvania. Findings were consistent between cohorts: we found rare heterozygous large-effect variants in 18.7% and 10.9% of low- and high-HDL-C patients, respectively. We also found common variant accumulation, indicated by extreme polygenic trait scores, in an additional 12.8% and 19.3% of overall cases of low- and high-HDL-C extremes, respectively. Thus, the genetic basis of extreme HDL-C concentrations encountered clinically is frequently polygenic, with contributions from both rare large-effect and common small-effect variants. Multiple types of genetic variants should be considered as contributing factors in patients with extreme dyslipidemia. Copyright © 2017 by the American Society for Biochemistry and Molecular Biology, Inc.

Sodium Handling Technology and Engineering Design of the Madison Dynamo Experiment.

NASA Astrophysics Data System (ADS)

Kendrick, R.; Forest, C. B.; O'Connell, R.; Wright, A.; Robinson, K.

1998-11-01

A new liquid metal MHD experiment is being constructed at the University of Wisconsin to test several key predictions of dynamo theory: magnetic instabilities driven by sheared flow, the effects of turbulence on current generation, and the back-reaction of the self-generated magnetic field on the fluid motion which brings saturation. This presentation describes the engineering design of the experiment, which is a 0.5 m radius spherical vessel, filled with liquid sodium at 150 degrees Celsius. The experiment is designed to achieve a magnetic Reynolds number in excess of 100, which requires approximately 80 Hp of mechanical drive, producing flow velocities in sodium of 15 m/s through impellers. Handling liquid sodium offers a number of technical challenges, but routine techniques have been developed over the past several decades for safely handling large quantities for the fast breeder reactor. The handling strategy is discussed, technical details concerning seals and pressurazation are presented, and safety elements are highlighted.

Discovery of Massive, Mostly Star Formation Quenched Galaxies with Extremely Large Lyα Equivalent Widths at z ˜ 3

NASA Astrophysics Data System (ADS)

Taniguchi, Yoshiaki; Kajisawa, Masaru; Kobayashi, Masakazu A. R.; Nagao, Tohru; Shioya, Yasuhiro; Scoville, Nick Z.; Sanders, David B.; Capak, Peter L.; Koekemoer, Anton M.; Toft, Sune; McCracken, Henry J.; Le Fèvre, Olivier; Tasca, Lidia; Sheth, Kartik; Renzini, Alvio; Lilly, Simon; Carollo, Marcella; Kovač, Katarina; Ilbert, Olivier; Schinnerer, Eva; Fu, Hai; Tresse, Laurence; Griffiths, Richard E.; Civano, Francesca

2015-08-01

We report a discovery of six massive galaxies with both extremely large Lyα equivalent widths (EWs) and evolved stellar populations at z ˜ 3. These MAssive Extremely STrong Lyα emitting Objects (MAESTLOs) have been discovered in our large-volume systematic survey for strong Lyα emitters (LAEs) with 12 optical intermediate-band data taken with Subaru/Suprime-Cam in the COSMOS field. Based on the spectral energy distribution fitting analysis for these LAEs, it is found that these MAESTLOs have (1) large rest-frame EWs of EW0 (Lyα) ˜ 100-300 Å, (2) M⋆ ˜ 1010.5-1011.1 M⊙, and (3) relatively low specific star formation rates of SFR/M⋆ ˜ 0.03-1 Gyr-1. Three of the six MAESTLOs have extended Lyα emission with a radius of several kiloparsecs, although they show very compact morphology in the HST/ACS images, which correspond to the rest-frame UV continuum. Since the MAESTLOs do not show any evidence for active galactic nuclei, the observed extended Lyα emission is likely to be caused by a star formation process including the superwind activity. We suggest that this new class of LAEs, MAESTLOs, provides a missing link from star-forming to passively evolving galaxies at the peak era of the cosmic star formation history. Based on observations with NASA/ESA Hubble Space Telescope, obtained at the Space Telescope Science Institute, which is operated by AURA, Inc., under NASA contract NAS 5-26555; also based on data collected at the Subaru Telescope, which is operated by the National Astronomical Observatory of Japan; and also based on data products from observations made with ESO Telescopes at the La Silla Paranal Observatory under ESO programme ID 179.A-2005 and on data products produced by TERAPIX and the Cambridge Astronomy Survey Unit on behalf of the UltraVISTA consortium.

7 CFR 58.443 - Whey handling.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Whey handling. 58.443 Section 58.443 Agriculture... Procedures § 58.443 Whey handling. (a) Adequate sanitary facilities shall be provided for the handling of whey. If outside, necessary precautions shall be taken to minimize flies, insects and development of...

7 CFR 945.9 - Ship or handle.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 8 2011-01-01 2011-01-01 false Ship or handle. 945.9 Section 945.9 Agriculture... DESIGNATED COUNTIES IN IDAHO, AND MALHEUR COUNTY, OREGON Order Regulating Handling Definitions § 945.9 Ship or handle. Ship or handle means to pack, sell, consign, transport or in any other way to place...

7 CFR 927.8 - Ship or handle.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Ship or handle. 927.8 Section 927.8 Agriculture... Order Regulating Handling Definitions § 927.8 Ship or handle. Ship or handle means to sell, deliver, consign, transport or ship pears within the production area or between the production area and any point...

7 CFR 927.8 - Ship or handle.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 8 2011-01-01 2011-01-01 false Ship or handle. 927.8 Section 927.8 Agriculture... Order Regulating Handling Definitions § 927.8 Ship or handle. Ship or handle means to sell, deliver, consign, transport or ship pears within the production area or between the production area and any point...

7 CFR 945.9 - Ship or handle.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Ship or handle. 945.9 Section 945.9 Agriculture... DESIGNATED COUNTIES IN IDAHO, AND MALHEUR COUNTY, OREGON Order Regulating Handling Definitions § 945.9 Ship or handle. Ship or handle means to pack, sell, consign, transport or in any other way to place...

7 CFR 927.8 - Ship or handle.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 8 2013-01-01 2013-01-01 false Ship or handle. 927.8 Section 927.8 Agriculture... Order Regulating Handling Definitions § 927.8 Ship or handle. Ship or handle means to sell, deliver, consign, transport or ship pears within the production area or between the production area and any point...

7 CFR 945.9 - Ship or handle.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 8 2013-01-01 2013-01-01 false Ship or handle. 945.9 Section 945.9 Agriculture... DESIGNATED COUNTIES IN IDAHO, AND MALHEUR COUNTY, OREGON Order Regulating Handling Definitions § 945.9 Ship or handle. Ship or handle means to pack, sell, consign, transport or in any other way to place...

7 CFR 927.8 - Ship or handle.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 8 2012-01-01 2012-01-01 false Ship or handle. 927.8 Section 927.8 Agriculture... Order Regulating Handling Definitions § 927.8 Ship or handle. Ship or handle means to sell, deliver, consign, transport or ship pears within the production area or between the production area and any point...

7 CFR 927.8 - Ship or handle.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 8 2014-01-01 2014-01-01 false Ship or handle. 927.8 Section 927.8 Agriculture... Order Regulating Handling Definitions § 927.8 Ship or handle. Ship or handle means to sell, deliver, consign, transport or ship pears within the production area or between the production area and any point...

The Vermicelli Handling Test: A Simple Quantitative Measure of Dexterous Forepaw Function in Rats

PubMed Central

Allred, Rachel P.; Adkins, DeAnna L.; Woodlee, Martin T.; Husbands, Lincoln C.; Maldonado, Mónica A.; Kane, Jacqueline R.; Schallert, Timothy; Jones, Theresa A.

2008-01-01

Loss of function in the hands occurs with many brain disorders, but there are few measures of skillful forepaw use in rats available to model these impairments that are both sensitive and simple to administer. Whishaw and Coles (1996) previously described the dexterous manner in which rats manipulate food items with their paws, including thin pieces of pasta. We set out to develop a measure of this food handling behavior that would be quantitative, easy to administer, sensitive to the effects of damage to sensory and motor systems of the CNS and useful for identifying the side of lateralized impairments. When rats handle 7 cm lengths of vermicelli, they manipulate the pasta by repeatedly adjusting the forepaw hold on the pasta piece. As operationally defined, these adjustments can be easily identified and counted by an experimenter without specialized equipment. After unilateral sensorimotor cortex (SMC) lesions, transient middle cerebral artery occlusion (MCAO) and striatal dopamine depleting (6-hydroxydopamine, 6-OHDA) lesions in adult rats, there were enduring reductions in adjustments made with the contralateral forepaw. Additional pasta handling characteristics distinguished between the lesion types. MCAO and 6-OHDA lesions increased the frequency of several identified atypical handling patterns. Severe dopamine depletion increased eating time and adjustments made with the ipsilateral forepaw. However, contralateral forepaw adjustment number most sensitively detected enduring impairments across lesion types. Because of its ease of administration and sensitivity to lateralized impairments in skilled forepaw use, this measure may be useful in rat models of upper extremity impairment. PMID:18325597

Statistical Extremes of Turbulence and a Cascade Generalisation of Euler's Gyroscope Equation

NASA Astrophysics Data System (ADS)

Tchiguirinskaia, Ioulia; Scherzer, Daniel

2016-04-01

Turbulence refers to a rather well defined hydrodynamical phenomenon uncovered by Reynolds. Nowadays, the word turbulence is used to designate the loss of order in many different geophysical fields and the related fundamental extreme variability of environmental data over a wide range of scales. Classical statistical techniques for estimating the extremes, being largely limited to statistical distributions, do not take into account the mechanisms generating such extreme variability. An alternative approaches to nonlinear variability are based on a fundamental property of the non-linear equations: scale invariance, which means that these equations are formally invariant under given scale transforms. Its specific framework is that of multifractals. In this framework extreme variability builds up scale by scale leading to non-classical statistics. Although multifractals are increasingly understood as a basic framework for handling such variability, there is still a gap between their potential and their actual use. In this presentation we discuss how to dealt with highly theoretical problems of mathematical physics together with a wide range of geophysical applications. We use Euler's gyroscope equation as a basic element in constructing a complex deterministic system that preserves not only the scale symmetry of the Navier-Stokes equations, but some more of their symmetries. Euler's equation has been not only the object of many theoretical investigations of the gyroscope device, but also generalised enough to become the basic equation of fluid mechanics. Therefore, there is no surprise that a cascade generalisation of this equation can be used to characterise the intermittency of turbulence, to better understand the links between the multifractal exponents and the structure of a simplified, but not simplistic, version of the Navier-Stokes equations. In a given way, this approach is similar to that of Lorenz, who studied how the flap of a butterfly wing could generate

Hypothenar hammer syndrome from ice hockey stick-handling.

PubMed

Zayed, Mohamed A; McDonald, Joey; Tittley, Jacques G

2013-11-01

Ulnar artery thrombosis and hypothenar hammer syndrome are rare vascular complications that could potentially occur with repeated blows or trauma to the hand. Although initially reported as an occupational hazard among laborers and craftsmen, it has been observed more recently among recreationalists and athletes. Until now, it has never been reported as a complication in ice hockey players. In this case report, a 26-year-old Canadian professional ice hockey player presented with acute dominant right hand paleness, coolness, and pain with hand use. The patient used a wooden hockey stick with a large knob of tape at the end of the handle, which he regularly gripped in the palm of his right hand to help with face-offs and general stick-handling. Sonographic evaluation demonstrated no arterial flow in the distal right ulnar artery distribution, and ulnar artery occlusion with no aneurysmal degeneration was confirmed by magnetic resonance angiogram. Intraarterial thrombolytic therapy was initiated, and subsequent serial angiograms demonstrated significant improvement in distal ulnar artery flow as well as recanalization of right hand deep palmar arch and digital arteries. The patient's symptoms resolved, and he was maintained on therapeutic anticoagulation for 3 months prior to returning to playing ice hockey professionally, but with a padded glove and no tape knob at the handle tip. This case highlights a unique presentation of hockey stick-handling causing ulnar artery thrombosis that was likely from repeated palmar hypothenar trauma. Appropriate diagnostic imaging, early intraarterial thrombolysis, and postoperative surveillance and follow-up were crucial for the successful outcome in this patient. Copyright © 2013 Elsevier Inc. All rights reserved.

The Gaia On-Board Scientific Data Handling

NASA Astrophysics Data System (ADS)

Arenou, F.; Babusiaux, C.; Chéreau, F.; Mignot, S.

2005-01-01

Because Gaia will perform a continuous all-sky survey at a medium (Spectro) or very high (Astro) angular resolution, the on-board processing needs to cope with a high variety of objects and densities which calls for generic and adaptive algorithms at the detection level, but not only. Consequently, the Pyxis scientific algorithms developed for the on-board data handling cover a large range of application: detection and confirmation of astronomical objects, background sky estimation, classification of detected objects, Near-Earth Objects onboard detection, and window selection and positioning. Very dense fields, where the real-time computing requirements should remain within fixed bounds, are particularly challenging. Another constraint stems from the limited telemetry bandwidth and an additional compromise has to be found between scientific requirements and constraints in terms of the mass, volume and power budgets of the satellite. The rationale for the on-board data handling procedure is described here, together with the developed algorithms, the main issues and the expected scientific performances in the Astro and Spectro instruments.

Sample Handling in Extreme Environments

NASA Technical Reports Server (NTRS)

Avellar, Louisa; Badescu, Mircea; Sherrit, Stewart; Bar-Cohen, Yoseph

2013-01-01

Harsh environments, such as that on Venus, preclude the use of existing equipment for functions that involve interaction with the environment. The operating limitations of current high temperature electronics are well below the actual temperature and pressure found on Venus (460 deg C and 92 atm), so proposed lander configurations typically include a pressure vessel where the science instruments are kept at Earth-like temperature and pressure (25 deg C and 1 atm). The purpose of this project was to develop and demonstrate a method for sample transfer from an external drill to internal science instruments for a lander on Venus. The initial concepts were string and pneumatically driven systems; and the latter system was selected for its ability to deliver samples at very high speed. The pneumatic system was conceived to be driven by the pressure difference between the Venusian atmosphere and the inside of the lander. The pneumatic transfer of a small capsule was demonstrated, and velocity data was collected from the lab experiment. The sample transfer system was modeled using CAD software and prototyped using 3D printing. General structural and thermal analyses were performed to approximate the proposed system's mass and effects on the temperature and pressure inside of the lander. Additionally, a sampler breadboard for use on Titan was tested and functionality problems were resolved.

Extreme hydrometeorological events in the Peruvian Central Andes during austral summer and their relationship with the large-scale circulation

NASA Astrophysics Data System (ADS)

Sulca, Juan C.

In this Master's dissertation, atmospheric circulation patterns associated with extreme hydrometeorological events in the Mantaro Basin, Peruvian Central Andes, and their teleconnections during the austral summer (December-January-February-March) are addressed. Extreme rainfall events in the Mantaro basin are related to variations of the large-scale circulation as indicated by the changing strength of the Bolivian High-Nordeste Low (BH-NL) system. Dry (wet) spells are associated with a weakening (strengthening) of the BH-NL system and reduced (enhanced) influx of moist air from the lowlands to the east due to strengthened westerly (easterly) wind anomalies at mid- and upper-tropospheric levels. At the same time extreme rainfall events of the opposite sign occur over northeastern Brazil (NEB) due to enhanced (inhibited) convective activity in conjunction with a strengthened (weakened) Nordeste Low. Cold episodes in the Mantaro Basin are grouped in three types: weak, strong and extraordinary cold episodes. Weak and strong cold episodes in the MB are mainly associated with a weakening of the BH-NL system due to tropical-extratropical interactions. Both types of cold episodes are associated with westerly wind anomalies at mid- and upper-tropospheric levels aloft the Peruvian Central Andes, which inhibit the influx of humid air masses from the lowlands to the east and hence limit the potential for development of convective cloud cover. The resulting clear sky conditions cause nighttime temperatures to drop, leading to cold extremes below the 10-percentile. Extraordinary cold episodes in the MB are associated with cold and dry polar air advection at all tropospheric levels toward the central Peruvian Andes. Therefore, weak and strong cold episodes in the MB appear to be caused by radiative cooling associated with reduced cloudiness, rather than cold air advection, while the latter plays an important role for extraordinary cold episodes only.

Microsurgery within reconstructive surgery of extremities.

PubMed

Pheradze, I; Pheradze, T; Tsilosani, G; Goginashvili, Z; Mosiava, T

2006-05-01

Reconstructive surgery of extremities is an object of a special attention of surgeons. Vessel and nerve damages, deficiency of soft tissue, bone, associated with infection results in a complete loss of extremity function, it also raises a question of amputation. The goal of the study was to improve the role of microsurgery in reconstructive surgery of limbs. We operated on 294 patients with various diseases and damages of extremities: pathology of nerves, vessels, tissue loss. An original method of treatment of large simultaneous functional defects of limbs has been used. Good functional and aesthetic results were obtained. Results of reconstructive operations on extremities might be improved by using of microsurgery methods. Microsurgery is deemed as a method of choice for extremities' reconstructive surgery as far as outcomes achieved through application of microsurgical technique significantly surpass the outcomes obtained through the use of routine surgical methods.

To what extent does variability of historical rainfall series influence extreme event statistics of sewer system surcharge and overflows?

PubMed

Schaarup-Jensen, K; Rasmussen, M R; Thorndahl, S

2009-01-01

In urban drainage modelling long-term extreme statistics has become an important basis for decision-making e.g. in connection with renovation projects. Therefore it is of great importance to minimize the uncertainties with regards to long-term prediction of maximum water levels and combined sewer overflow (CSO) in drainage systems. These uncertainties originate from large uncertainties regarding rainfall inputs, parameters, and assessment of return periods. This paper investigates how the choice of rainfall time series influences the extreme events statistics of max water levels in manholes and CSO volumes. Traditionally, long-term rainfall series, from a local rain gauge, are unavailable. In the present case study, however, long and local rain series are available. 2 rainfall gauges have recorded events for approximately 9 years at 2 locations within the catchment. Beside these 2 gauges another 7 gauges are located at a distance of max 20 kilometers from the catchment. All gauges are included in the Danish national rain gauge system which was launched in 1976. The paper describes to what extent the extreme events statistics based on these 9 series diverge from each other and how this diversity can be handled, e.g. by introducing an "averaging procedure" based on the variability within the set of statistics. All simulations are performed by means of the MOUSE LTS model.

Long-term records reveal decoupling of nitrogen and phosphorus cycles in a large, urban lake in response to an extreme rainfall event

NASA Astrophysics Data System (ADS)

Corman, J. R.; Loken, L. C.; Oliver, S. K.; Collins, S.; Butitta, V.; Stanley, E. H.

2017-12-01

Extreme events can play powerful roles in shifting ecosystem processes. In lakes, heavy rainfall can transport large amounts of particulates and dissolved nutrients into the water column and, potentially, alter biogeochemical cycling. However, the impacts of extreme rainfall events are often difficult to study due to a lack of long-term records. In this paper, we combine daily discharge records with long-term lake water quality information collected by the North Temperate Lakes Long-Term Ecological Research (NTL LTER) site to investigate the impacts of extreme events on nutrient cycling in lakes. We focus on Lake Mendota, an urban lake within the Yahara River Watershed in Madison, Wisconsin, USA, where nutrient data are available at least seasonally from 1995 - present. In June 2008, precipitation amounts in the Yahara watershed were 400% above normal values, triggering the largest discharge event on record for the 40 years of monitoring at the streamgage station; hence, we are able to compare water quality records before and after this event as a case study of how extreme rain events couple or decouple lake nutrient cycling. Following the extreme event, the lake-wide mass of nitrogen and phosphorus increased in the summer of 2008 by 35% and 21%, respectively, shifting lake stoichiometry by increasing N:P ratios (Figure 1). Nitrogen concentrations remained elevated longer than phosphorus, suggesting (1) that nitrogen inputs into the lake were sustained longer than phosphorus (i.e., a "smear" versus "pulse" loading of nitrogen versus phosphorus, respectively, in response to the extreme event) and/or (2) that in-lake biogeochemical processing was more efficient at removing phosphorus compared to nitrogen. While groundwater loading data are currently unavailable to test the former hypothesis, preliminary data from surficial nitrogen and phosphorus loading to Lake Mendota (available for 2011 - 2013) suggest that nitrogen removal efficiency is less than phosphorus

A Coupled Approach with Stochastic Rainfall-Runoff Simulation and Hydraulic Modeling for Extreme Flood Estimation on Large Watersheds

NASA Astrophysics Data System (ADS)

Paquet, E.

2015-12-01

The SCHADEX method aims at estimating the distribution of peak and daily discharges up to extreme quantiles. It couples a precipitation probabilistic model based on weather patterns, with a stochastic rainfall-runoff simulation process using a conceptual lumped model. It allows exploring an exhaustive set of hydrological conditions and watershed responses to intense rainfall events. Since 2006, it has been widely applied in France to about one hundred watersheds for dam spillway design, and also aboard (Norway, Canada and central Europe among others). However, its application to large watersheds (above 10 000 km²) faces some significant issues: spatial heterogeneity of rainfall and hydrological processes and flood peak damping due to hydraulic effects (flood plains, natural or man-made embankment) being the more important. This led to the development of an extreme flood simulation framework for large and heterogeneous watersheds, based on the SCHADEX method. Its main features are: Division of the large (or main) watershed into several smaller sub-watersheds, where the spatial homogeneity of the hydro-meteorological processes can reasonably be assumed, and where the hydraulic effects can be neglected. Identification of pilot watersheds where discharge data are available, thus where rainfall-runoff models can be calibrated. They will be parameters donors to non-gauged watersheds. Spatially coherent stochastic simulations for all the sub-watersheds at the daily time step. Identification of a selection of simulated events for a given return period (according to the distribution of runoff volumes at the scale of the main watershed). Generation of the complete hourly hydrographs at each of the sub-watersheds outlets. Routing to the main outlet with hydraulic 1D or 2D models. The presentation will be illustrated with the case-study of the Isère watershed (9981 km), a French snow-driven watershed. The main novelties of this method will be underlined, as well as its

Climate Impacts on Extreme Energy Consumption of Different Types of Buildings

PubMed Central

Li, Mingcai; Shi, Jun; Guo, Jun; Cao, Jingfu; Niu, Jide; Xiong, Mingming

2015-01-01

Exploring changes of building energy consumption and its relationships with climate can provide basis for energy-saving and carbon emission reduction. Heating and cooling energy consumption of different types of buildings during 1981-2010 in Tianjin city, was simulated by using TRNSYS software. Daily or hourly extreme energy consumption was determined by percentile methods, and the climate impact on extreme energy consumption was analyzed. The results showed that days of extreme heating consumption showed apparent decrease during the recent 30 years for residential and large venue buildings, whereas days of extreme cooling consumption increased in large venue building. No significant variations were found for the days of extreme energy consumption for commercial building, although a decreasing trend in extreme heating energy consumption. Daily extreme energy consumption for large venue building had no relationship with climate parameters, whereas extreme energy consumption for commercial and residential buildings was related to various climate parameters. Further multiple regression analysis suggested heating energy consumption for commercial building was affected by maximum temperature, dry bulb temperature, solar radiation and minimum temperature, which together can explain 71.5 % of the variation of the daily extreme heating energy consumption. The daily extreme cooling energy consumption for commercial building was only related to the wet bulb temperature (R2= 0.382). The daily extreme heating energy consumption for residential building was affected by 4 climate parameters, but the dry bulb temperature had the main impact. The impacts of climate on hourly extreme heating energy consumption has a 1-3 hour delay in all three types of buildings, but no delay was found in the impacts of climate on hourly extreme cooling energy consumption for the selected buildings. PMID:25923205

A rational decision rule with extreme events.

PubMed

Basili, Marcello

2006-12-01

Risks induced by extreme events are characterized by small or ambiguous probabilities, catastrophic losses, or windfall gains. Through a new functional, that mimics the restricted Bayes-Hurwicz criterion within the Choquet expected utility approach, it is possible to represent the decisionmaker behavior facing both risky (large and reliable probability) and extreme (small or ambiguous probability) events. A new formalization of the precautionary principle (PP) is shown and a new functional, which encompasses both extreme outcomes and expectation of all the possible results for every act, is claimed.

Polygenic determinants in extremes of high-density lipoprotein cholesterol[S

PubMed Central

Dron, Jacqueline S.; Wang, Jian; Low-Kam, Cécile; Khetarpal, Sumeet A.; Robinson, John F.; McIntyre, Adam D.; Ban, Matthew R.; Cao, Henian; Rhainds, David; Dubé, Marie-Pierre; Rader, Daniel J.; Lettre, Guillaume; Tardif, Jean-Claude

2017-01-01

HDL cholesterol (HDL-C) remains a superior biochemical predictor of CVD risk, but its genetic basis is incompletely defined. In patients with extreme HDL-C concentrations, we concurrently evaluated the contributions of multiple large- and small-effect genetic variants. In a discovery cohort of 255 unrelated lipid clinic patients with extreme HDL-C levels, we used a targeted next-generation sequencing panel to evaluate rare variants in known HDL metabolism genes, simultaneously with common variants bundled into a polygenic trait score. Two additional cohorts were used for validation and included 1,746 individuals from the Montréal Heart Institute Biobank and 1,048 individuals from the University of Pennsylvania. Findings were consistent between cohorts: we found rare heterozygous large-effect variants in 18.7% and 10.9% of low- and high-HDL-C patients, respectively. We also found common variant accumulation, indicated by extreme polygenic trait scores, in an additional 12.8% and 19.3% of overall cases of low- and high-HDL-C extremes, respectively. Thus, the genetic basis of extreme HDL-C concentrations encountered clinically is frequently polygenic, with contributions from both rare large-effect and common small-effect variants. Multiple types of genetic variants should be considered as contributing factors in patients with extreme dyslipidemia. PMID:28870971

An artificial perch to help Snail Kites handle an exotic Apple Snail

USGS Publications Warehouse

Pias, Kyle E.; Welch, Zach C.; Kitchens, Wiley M.

2012-01-01

In the United States, the Snail Kite (Rostrhamus sociabilis plumbeus) is a federally endangered species and restricted to the wetlands of south-central Florida where the current population numbers less than 1,500. The Snail Kite is an extreme dietary specialist, previously feeding almost exclusively on one species of snail, the Florida Apple Snail (Pomacea paludosa). Within the past decade, an exotic species of apple snail, the Island Apple Snail (Pomacea insularum), has become established on lakes in central Florida. Island Apple Snails are larger than the native Florida Apple Snails, and Snail Kites handle the exotic snails less efficiently. Juvenile Snail Kites, in particular, have lower daily energy balances while feeding on Island Apple Snails. An inexpensive, easy-to-construct platform was developed that would provide Snail Kites with a flat, stable surface on which to extract snails. The platform has the potential to reduce the difficulties Snail Kites experience when handling exotic snails, and may benefit the Snail Kite population as a whole. Initial observations indicate that Snail Kites use the platforms frequently, and snails extracted at the platforms are larger than snails extracted at other perches.

Optical Design for Extremely Large Telescope Adaptive Optics Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bauman, Brian J.

2003-01-01

Designing an adaptive optics (AO) system for extremely large telescopes (ELT's) will present new optical engineering challenges. Several of these challenges are addressed in this work, including first-order design of multi-conjugate adaptive optics (MCAO) systems, pyramid wavefront sensors (PWFS's), and laser guide star (LGS) spot elongation. MCAO systems need to be designed in consideration of various constraints, including deformable mirror size and correction height. The y,{bar y} method of first-order optical design is a graphical technique that uses a plot with marginal and chief ray heights as coordinates; the optical system is represented as a segmented line. This method ismore » shown to be a powerful tool in designing MCAO systems. From these analyses, important conclusions about configurations are derived. PWFS's, which offer an alternative to Shack-Hartmann (SH) wavefront sensors (WFS's), are envisioned as the workhorse of layer-oriented adaptive optics. Current approaches use a 4-faceted glass pyramid to create a WFS analogous to a quad-cell SH WFS. PWFS's and SH WFS's are compared and some newly-considered similarities and PWFS advantages are presented. Techniques to extend PWFS's are offered: First, PWFS's can be extended to more pixels in the image by tiling pyramids contiguously. Second, pyramids, which are difficult to manufacture, can be replaced by less expensive lenslet arrays. An approach is outlined to convert existing SH WFS's to PWFS's for easy evaluation of PWFS's. Also, a demonstration of PWFS's in sensing varying amounts of an aberration is presented. For ELT's, the finite altitude and finite thickness of LGS's means that the LGS will appear elongated from the viewpoint of subapertures not directly under the telescope. Two techniques for dealing with LGS spot elongation in SH WFS's are presented. One method assumes that the laser will be pulsed and uses a segmented micro-electromechanical system (MEMS) to track the LGS light subaperture

Handling an Asthma Flare-Up

MedlinePlus

... Videos for Educators Search English Español Handling an Asthma Flare-Up KidsHealth / For Kids / Handling an Asthma ... español Cómo controlar las crisis asmáticas What's an Asthma Flare-Up? If you have asthma , you probably ...

7 CFR 1205.312 - Handle.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE COTTON RESEARCH AND PROMOTION Cotton Research and Promotion Order Definitions § 1205.312 Handle. Handle means to harvest, gin, warehouse, compress, purchase, market, transport, or otherwise acquire ownership or control of cotton. [31 FR 16758...

7 CFR 983.14 - Handle.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE PISTACHIOS GROWN IN CALIFORNIA, ARIZONA, AND NEW MEXICO Definitions § 983.14 Handle. Handle means to engage in: (a) Receiving pistachios; (b) Hulling and drying pistachios; (c) Further preparing pistachios by sorting, sizing, shelling, roasting...

7 CFR 1219.11 - Handle.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.11 Handle. Handle means to pack, process, transport, purchase, or in any other way to place or cause Hass avocados...

7 CFR 1219.11 - Handle.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.11 Handle. Handle means to pack, process, transport, purchase, or in any other way to place or cause Hass avocados...

7 CFR 1219.11 - Handle.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.11 Handle. Handle means to pack, process, transport, purchase, or in any other way to place or cause Hass avocados...

7 CFR 1219.11 - Handle.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.11 Handle. Handle means to pack, process, transport, purchase, or in any other way to place or cause Hass avocados...

Heavy Tail Behavior of Rainfall Extremes across Germany

NASA Astrophysics Data System (ADS)

Castellarin, A.; Kreibich, H.; Vorogushyn, S.; Merz, B.

2017-12-01

Distributions are termed heavy-tailed if extreme values are more likely than would be predicted by probability distributions that have exponential asymptotic behavior. Heavy-tail behavior often leads to surprise, because historical observations can be a poor guide for the future. Heavy-tail behavior seems to be widespread for hydro-meteorological extremes, such as extreme rainfall and flood events. To date there have been only vague hints to explain under which conditions these extremes show heavy-tail behavior. We use an observational data set consisting of 11 climate variables at 1440 stations across Germany. This homogenized, gap-free data set covers 110 years (1901-2010) at daily resolution. We estimate the upper tail behavior, including its uncertainty interval, of daily precipitation extremes for the 1,440 stations at the annual and seasonal time scales. Different tail indicators are tested, including the shape parameter of the Generalized Extreme Value distribution, the upper tail ratio and the obesity index. In a further step, we explore to which extent the tail behavior can be explained by geographical and climate factors. A large number of characteristics is derived, such as station elevation, degree of continentality, aridity, measures for quantifying the variability of humidity and wind velocity, or event-triggering large-scale atmospheric situation. The link between the upper tail behavior and these characteristics is investigated via data mining methods capable of detecting non-linear relationships in large data sets. This exceptionally rich observational data set, in terms of number of stations, length of time series and number of explaining variables, allows insights into the upper tail behavior which is rarely possible given the typical observational data sets available.

Performance of the Magnetospheric Multiscale central instrument data handling

NASA Astrophysics Data System (ADS)

Klar, Robert A.; Miller, Scott A.; Brysch, Michael L.; Bertrand, Allison R.

In order to study the fundamental physical processes of magnetic reconnection, particle acceleration and turbulence, the Magnetospheric Multiscale (MMS) mission employs a constellation of four identically configured observatories, each with a suite of complementary science instruments. Southwest Research Institute® (SwRI® ) developed the Central Instrument Data Processor (CIDP) to handle the large data volume associated with these instruments. The CIDP is an integrated access point between the instruments and the spacecraft. It provides synchronization pulses, relays telecommands, and gathers instrument housekeeping telemetry. It collects science data from the instruments and stores it to a mass memory for later playback to a ground station. This paper retrospectively examines the data handling performance realized by the CIDP implementation. It elaborates on some of the constraints on the hardware and software designs and the resulting effects on performance. For the hardware, it discusses the limitations of the front-end electronics input/output (I/O) architecture and associated mass memory buffering. For the software, it discusses the limitations of the Consultative Committee for Space Data Systems (CCSDS) File Delivery Protocol (CFDP) implementation and the data structure choices for file management. It also describes design changes that improve data handling performance in newer designs.

Extreme Conditions Modeling Workshop Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coe, R. G.; Neary, V. S.; Lawson, M. J.

2014-07-01

Sandia National Laboratories (SNL) and the National Renewable Energy Laboratory (NREL) hosted the Wave Energy Converter (WEC) Extreme Conditions Modeling (ECM) Workshop in Albuquerque, NM on May 13th-14th, 2014. The objective of the workshop was to review the current state of knowledge on how to model WECs in extreme conditions (e.g. hurricanes and other large storms) and to suggest how U.S. Department of Energy (DOE) and national laboratory resources could be used to improve ECM methods for the benefit of the wave energy industry.

7 CFR 1216.12 - Handle.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE PEANUT PROMOTION, RESEARCH, AND INFORMATION ORDER Peanut Promotion, Research, and Information Order Definitions § 1216.12 Handle. Handle means... peanuts and in the shipment (except as a common or contract carrier of peanuts owned by another) or sale...

7 CFR 1216.12 - Handle.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE PEANUT PROMOTION, RESEARCH, AND INFORMATION ORDER Peanut Promotion, Research, and Information Order Definitions § 1216.12 Handle. Handle means... peanuts and in the shipment (except as a common or contract carrier of peanuts owned by another) or sale...

7 CFR 926.9 - Handle.

Code of Federal Regulations, 2010 CFR

2010-01-01

... the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and... REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.9 Handle. Handle... cranberries or processed cranberries up to, but not including, the retail level. Effective Date Note: At 71 FR...

Handling qualities criteria for the space shuttle orbiter during the terminal phase of flight

NASA Technical Reports Server (NTRS)

Stapleford, R. L.; Klein, R. H.; Hob, R. H.

1972-01-01

It was found that large portions of the military handling qualities specification are directly applicable. However a number of additional and substitute criteria are recommended for areas not covered or inadequately covered in the military specification. Supporting pilot/vehicle analyses and simulation experiments were conducted and are described. Results are also presented of analytical and simulator evaluations of three specific interim Orbiter designs which provided a test of the proposed handling qualities criteria. The correlations between the analytical and experimental evaluations were generally excellent.

MSL's Widgets: Adding Rebustness to Martian Sample Acquisition, Handling, and Processing

NASA Technical Reports Server (NTRS)

Roumeliotis, Chris; Kennedy, Brett; Lin, Justin; DeGrosse, Patrick; Cady, Ian; Onufer, Nicholas; Sigel, Deborah; Jandura, Louise; Anderson, Robert; Katz, Ira;

Semi-supervised and unsupervised extreme learning machines.

PubMed

Huang, Gao; Song, Shiji; Gupta, Jatinder N D; Wu, Cheng

2014-12-01

Extreme learning machines (ELMs) have proven to be efficient and effective learning mechanisms for pattern classification and regression. However, ELMs are primarily applied to supervised learning problems. Only a few existing research papers have used ELMs to explore unlabeled data. In this paper, we extend ELMs for both semi-supervised and unsupervised tasks based on the manifold regularization, thus greatly expanding the applicability of ELMs. The key advantages of the proposed algorithms are as follows: 1) both the semi-supervised ELM (SS-ELM) and the unsupervised ELM (US-ELM) exhibit learning capability and computational efficiency of ELMs; 2) both algorithms naturally handle multiclass classification or multicluster clustering; and 3) both algorithms are inductive and can handle unseen data at test time directly. Moreover, it is shown in this paper that all the supervised, semi-supervised, and unsupervised ELMs can actually be put into a unified framework. This provides new perspectives for understanding the mechanism of random feature mapping, which is the key concept in ELM theory. Empirical study on a wide range of data sets demonstrates that the proposed algorithms are competitive with the state-of-the-art semi-supervised or unsupervised learning algorithms in terms of accuracy and efficiency.

The natural angle between the hand and handle and the effect of handle orientation on wrist radial/ulnar deviation during maximal push exertions.

PubMed

Young, Justin G; Lin, Jia-Hua; Chang, Chien-Chi; McGorry, Raymond W

2013-01-01

The purpose of this experiment was to quantify the natural angle between the hand and a handle, and to investigate three design factors: handle rotation, handle tilt and between-handle width on the natural angle as well as resultant wrist radial/ulnar deviation ('RUD') for pushing tasks. Photographs taken of the right upper limb of 31 participants (14 women and 17 men) performing maximal seated push exertions on different handles were analysed. Natural hand/handle angle and RUD were assessed. It was found that all of the three design factors significantly affected natural handle angle and wrist RUD, but participant gender did not. The natural angle between the hand and the cylindrical handle was 65 ± 7°. Wrist deviation was reduced for handles that were rotated 0° (horizontal) and at the narrow width (31 cm). Handles that were tilted forward 15° reduced radial deviation consistently (12-13°) across handle conditions. Manual materials handling (MMH) tasks involving pushing have been related to increased risk of musculoskeletal injury. This study shows that handle orientation influences hand and wrist posture during pushing, and suggests that the design of push handles on carts and other MMH aids can be improved by adjusting their orientation to fit the natural interface between the hand and handle.

7 CFR 1207.307 - Handle.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.307 Handle. Handle means to grade, pack, process, sell, transport, purchase, or in any other way to place potatoes or cause potatoes to be placed in the...

7 CFR 1219.11 - Handle.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Handle. 1219.11 Section 1219.11 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS.... Handle means to pack, process, transport, purchase, or in any other way to place or cause Hass avocados...

21 CFR 820.140 - Handling.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Handling. 820.140 Section 820.140 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES..., contamination, or other adverse effects to product do not occur during handling. ...

9 CFR 3.118 - Handling.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Handling. 3.118 Section 3.118 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Marine...

9 CFR 3.118 - Handling.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Handling. 3.118 Section 3.118 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Marine...

9 CFR 3.118 - Handling.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Handling. 3.118 Section 3.118 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Marine...

9 CFR 3.118 - Handling.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Handling. 3.118 Section 3.118 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Marine...

9 CFR 3.118 - Handling.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Handling. 3.118 Section 3.118 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Marine...

7 CFR 1207.307 - Handle.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.307 Handle. Handle means to grade, pack, process, sell, transport, purchase, or in any other way to place potatoes or cause potatoes to be placed in the...

7 CFR 1207.307 - Handle.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.307 Handle. Handle means to grade, pack, process, sell, transport, purchase, or in any other way to place potatoes or cause potatoes to be placed in the...

7 CFR 1207.307 - Handle.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.307 Handle. Handle means to grade, pack, process, sell, transport, purchase, or in any other way to place potatoes or cause potatoes to be placed in the...

7 CFR 1207.307 - Handle.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.307 Handle. Handle means to grade, pack, process, sell, transport, purchase, or in any other way to place potatoes or cause potatoes to be placed in the...

A single pH fluorescent probe for biosensing and imaging of extreme acidity and extreme alkalinity.

PubMed

Chao, Jian-Bin; Wang, Hui-Juan; Zhang, Yong-Bin; Li, Zhi-Qing; Liu, Yu-Hong; Huo, Fang-Jun; Yin, Cai-Xia; Shi, Ya-Wei; Wang, Juan-Juan

2017-07-04

A simple tailor-made pH fluorescent probe 2-benzothiazole (N-ethylcarbazole-3-yl) hydrazone (Probe) is facilely synthesized by the condensation reaction of 2-hydrazinobenzothiazole with N-ethylcarbazole-3-formaldehyde, which is a useful fluorescent probe for monitoring extremely acidic and alkaline pH, quantitatively. The pH titrations indicate that Probe displays a remarkable emission enhancement with a pK a of 2.73 and responds linearly to minor pH fluctuations within the extremely acidic range of 2.21-3.30. Interestingly, Probe also exhibits strong pH-dependent characteristics with pK a 11.28 and linear response to extreme-alkalinity range of 10.41-12.43. In addition, Probe shows a large Stokes shift of 84 nm under extremely acidic and alkaline conditions, high selectivity, excellent sensitivity, good water-solubility and fine stability, all of which are favorable for intracellular pH imaging. The probe is further successfully applied to image extremely acidic and alkaline pH values fluctuations in E. coli cells. Copyright © 2017 Elsevier B.V. All rights reserved.

Relationship between climate extremes in Romania and their connection to large-scale air circulation

NASA Astrophysics Data System (ADS)

Barbu, Nicu; Ştefan, Sabina

2015-04-01

The aim of this paper is to investigate the connection between climate extremes (temperature and precipitation) in Romania and large-scale air circulation. Daily observational data of maximum air temperature and amount of precipitation for the period 1961-2010 were used to compute two seasonal indices associated with temperature and precipitation, quantifying their frequency, as follows: frequency of very warm days (FTmax90 ≥ 90th percentile), frequency of very wet days (FPp90; daily precipitation amount ≥ 90th percentile). Seasonally frequency of circulation types were calculated from daily circulation types determined by using two objective catalogues (GWT - GrossWetter-Typen and WLK - WetterLargenKlassifikation) from the COST733Action. Daily reanalysis data sets (sea level pressure, geopotential height at 925 and 500 hPa, u and v components of wind vector at 700 hPa and precipitable water content for the entire atmospheric column) build up by NCEP/NCAR, with 2.5°/2.5° lat/lon spatial resolution, were used to determine the circulation types. In order to select the optimal domain size related to the FTmax90 and the FPp90, the explained variance (EV) has been used. The EV determines the relation between the variance among circulation types and the total variance of the variable under consideration. This method quantifies the discriminatory power of a classification. The relationships between climate extremes in Romania and large-scale air circulation were investigated by using multiple linear regression model (MLRM), the predictands are FTmax90 and FPp90 and the circulation types were used as predictors. In order to select the independent predictors to build the MLRM the collinearity and multicollinearity analysis were performed. The study period is dividend in two periods: the period 1961-2000 is used to train the MLRM and the period 2001-2010 is used to validate the MLRM. The analytical relationship obtained by using MLRM can be used for future projection

Spatial dependence of extreme rainfall

NASA Astrophysics Data System (ADS)

Radi, Noor Fadhilah Ahmad; Zakaria, Roslinazairimah; Satari, Siti Zanariah; Azman, Muhammad Az-zuhri

2017-05-01

This study aims to model the spatial extreme daily rainfall process using the max-stable model. The max-stable model is used to capture the dependence structure of spatial properties of extreme rainfall. Three models from max-stable are considered namely Smith, Schlather and Brown-Resnick models. The methods are applied on 12 selected rainfall stations in Kelantan, Malaysia. Most of the extreme rainfall data occur during wet season from October to December of 1971 to 2012. This period is chosen to assure the available data is enough to satisfy the assumption of stationarity. The dependence parameters including the range and smoothness, are estimated using composite likelihood approach. Then, the bootstrap approach is applied to generate synthetic extreme rainfall data for all models using the estimated dependence parameters. The goodness of fit between the observed extreme rainfall and the synthetic data is assessed using the composite likelihood information criterion (CLIC). Results show that Schlather model is the best followed by Brown-Resnick and Smith models based on the smallest CLIC's value. Thus, the max-stable model is suitable to be used to model extreme rainfall in Kelantan. The study on spatial dependence in extreme rainfall modelling is important to reduce the uncertainties of the point estimates for the tail index. If the spatial dependency is estimated individually, the uncertainties will be large. Furthermore, in the case of joint return level is of interest, taking into accounts the spatial dependence properties will improve the estimation process.

Automatic sequential fluid handling with multilayer microfluidic sample isolated pumping

PubMed Central

Liu, Jixiao; Fu, Hai; Yang, Tianhang; Li, Songjing

2015-01-01

To sequentially handle fluids is of great significance in quantitative biology, analytical chemistry, and bioassays. However, the technological options are limited when building such microfluidic sequential processing systems, and one of the encountered challenges is the need for reliable, efficient, and mass-production available microfluidic pumping methods. Herein, we present a bubble-free and pumping-control unified liquid handling method that is compatible with large-scale manufacture, termed multilayer microfluidic sample isolated pumping (mμSIP). The core part of the mμSIP is the selective permeable membrane that isolates the fluidic layer from the pneumatic layer. The air diffusion from the fluidic channel network into the degassing pneumatic channel network leads to fluidic channel pressure variation, which further results in consistent bubble-free liquid pumping into the channels and the dead-end chambers. We characterize the mμSIP by comparing the fluidic actuation processes with different parameters and a flow rate range of 0.013 μl/s to 0.097 μl/s is observed in the experiments. As the proof of concept, we demonstrate an automatic sequential fluid handling system aiming at digital assays and immunoassays, which further proves the unified pumping-control and suggests that the mμSIP is suitable for functional microfluidic assays with minimal operations. We believe that the mμSIP technology and demonstrated automatic sequential fluid handling system would enrich the microfluidic toolbox and benefit further inventions. PMID:26487904

WASTE HANDLING BUILDING ELECTRICAL SYSTEM DESCRIPTION DOCUMENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

S.C. Khamamkar

2000-06-23

The Waste Handling Building Electrical System performs the function of receiving, distributing, transforming, monitoring, and controlling AC and DC power to all waste handling building electrical loads. The system distributes normal electrical power to support all loads that are within the Waste Handling Building (WHB). The system also generates and distributes emergency power to support designated emergency loads within the WHB within specified time limits. The system provides the capability to transfer between normal and emergency power. The system provides emergency power via independent and physically separated distribution feeds from the normal supply. The designated emergency electrical equipment will bemore » designed to operate during and after design basis events (DBEs). The system also provides lighting, grounding, and lightning protection for the Waste Handling Building. The system is located in the Waste Handling Building System. The system consists of a diesel generator, power distribution cables, transformers, switch gear, motor controllers, power panel boards, lighting panel boards, lighting equipment, lightning protection equipment, control cabling, and grounding system. Emergency power is generated with a diesel generator located in a QL-2 structure and connected to the QL-2 bus. The Waste Handling Building Electrical System distributes and controls primary power to acceptable industry standards, and with a dependability compatible with waste handling building reliability objectives for non-safety electrical loads. It also generates and distributes emergency power to the designated emergency loads. The Waste Handling Building Electrical System receives power from the Site Electrical Power System. The primary material handling power interfaces include the Carrier/Cask Handling System, Canister Transfer System, Assembly Transfer System, Waste Package Remediation System, and Disposal Container Handling Systems. The system interfaces with the MGR

50 CFR 14.111 - Handling.

Code of Federal Regulations, 2010 CFR

2010-10-01

... and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR TAKING, POSSESSION..., EXPORTATION, AND TRANSPORTATION OF WILDLIFE Standards for the Humane and Healthful Transport of Wild Mammals and Birds to the United States § 14.111 Handling. (a) Care shall be exercised to avoid handling the...

Fluid handling equipment: A compilation

NASA Technical Reports Server (NTRS)

1976-01-01

Devices and techniques used in fluid-handling and vacuum systems are described. Section 1 presents several articles on fluid lines and tubing. Section 2 describes a number of components such as valves, filters, and regulators. The last section contains descriptions of a number of innovative fluid-handling systems.

SLUG HANDLING DEVICES

DOEpatents

Gentry, J.R.

1958-09-16

A device is described for handling fuel elements of a neutronic reactor. The device consists of two concentric telescoped contalners that may fit about the fuel element. A number of ratchet members, equally spaced about the entrance to the containers, are pivoted on the inner container and spring biased to the outer container so thnt they are forced to hear against and hold the fuel element, the weight of which tends to force the ratchets tighter against the fuel element. The ratchets are released from their hold by raising the inner container relative to the outer memeber. This device reduces the radiation hazard to the personnel handling the fuel elements.

Large-scale factors in tropical and extratropical cyclone transition and extreme weather events.

PubMed

Pezza, Alexandre Bernardes; Simmonds, Ian

2008-12-01

Transition mechanisms characterizing changes from hurricanes to midlatitude cyclones and vice-versa (extratropical and tropical transition) have become a topic of increasing interest, partially because of their association with recent unusual storms that have developed in different ocean basins of both hemispheres. The aim of this work is to discuss some recent cases of transition and highly unusual hurricane developments and to address some of their wider implications for climate science. Frequently those dramatic cyclones are responsible for severe weather, potentially causing significant damage to property and infrastructure. An additional manifestation discussed here is their association with cold surges, a topic that has been very little explored in the literature. In the Southern Hemisphere, the first South Atlantic hurricane, Catarina, developed in March 2004 under very unusual large-scale conditions. That exceptional cyclone is viewed as a case of tropical transition facilitated by a well-developed blocking structure. A new index for monitoring tropical transition in the subtropical South Atlantic is discussed. This "South Atlantic index" is used to show that the unusual flow during and prior to Catarina's genesis can be attributed to tropical/extratropical interaction mechanisms. The "Donald Duck" case in Australia and Vince in the North Atlantic have also been examined and shown to belong to a category of hybrid-transitioning systems that will achieve at least partial tropical transition. While clearly more research is needed on the topic of transition, as we gain further insight, it is becoming increasingly apparent that features of large-scale circulation do play a fundamental role. A complex interaction between an extratropical transition case and an extreme summer cold surge affecting southeastern Australia is discussed as an example of wider climate implications.

Origin of the extremely large magnetoresistance in topological semimetal PtS n4

NASA Astrophysics Data System (ADS)

Luo, X.; Xiao, R. C.; Chen, F. C.; Yan, J.; Pei, Q. L.; Sun, Y.; Lu, W. J.; Tong, P.; Sheng, Z. G.; Zhu, X. B.; Song, W. H.; Sun, Y. P.

2018-05-01

PtS n4 with extremely large magnetoresistance (XMR), a fascinating topological material platform, hosts a novel topological structure and Dirac node arcs, in which the Dirac nodes form closed loops in the momentum space. Here we performed the angular dependent magnetoresistivity (AMR), Hall effect, heat capacity measurements, and first-principles calculations to study the electronic properties of topological semimetal PtS n4 . There are some interesting observations on PtS n4 . (1) In the different experimental probes, we observed the anomalies around T ˜55 K . Significant changes of the transport results and the heat capacity have been observed, indicating successive Fermi surface reconstruction induced by the temperature. It means there is Lifshitz transition (LT) induced by the temperature in PtS n4 . (2) The perfect compensation between the electron and hole has been found around T ˜30 K , where the XMR appears, which is confirmed by the Hall effect measurements and the first-principles calculations. The XMR effect in PtS n4 is suggested to originate from the combination of the electron-hole compensation and a particular orbital texture on the electron pocket. Meanwhile, we also found that LT seems to serve as a knob for the novel topological properties in two-dimensional (2D) topological semimetals (TSMs).

Large-Scale Skin Resurfacing of the Upper Extremity in Pediatric Patients Using a Pre-Expanded Intercostal Artery Perforator Flap.

PubMed

Wei, Jiao; Herrler, Tanja; Gu, Bin; Yang, Mei; Li, Qingfeng; Dai, Chuanchang; Xie, Feng

2018-05-01

The repair of extensive upper limb skin lesions in pediatric patients is extremely challenging due to substantial limitations of flap size and donor-site morbidity. We aimed to create an oversize preexpanded flap based on intercostal artery perforators for large-scale resurfacing of the upper extremity in children. Between March 2013 and August 2016, 11 patients underwent reconstructive treatment for extensive skin lesions in the upper extremity using a preexpanded intercostal artery perforator flap. Preoperatively, 2 to 4 candidate perforators were selected as potential pedicle vessels based on duplex ultrasound examination. After tissue expander implantation in the thoracodorsal area, regular saline injections were performed until the expanded flap was sufficient in size. Then, a pedicled flap was formed to resurface the skin lesion of the upper limb. The pedicles were transected 3 weeks after flap transfer. Flap survival, complications, and long-term outcome were evaluated. The average time of tissue expansion was 133 days with a mean final volume of 1713 mL. The thoracoabdominal flaps were based on 2 to 6 pedicles and used to resurface a mean skin defect area of 238 cm ranging from 180 to 357 cm. In all cases, primary donor-site closure was achieved. Marginal necrosis was seen in 5 cases. The reconstructed limbs showed satisfactory outcome in both aesthetic and functional aspects. The preexpanded intercostal artery perforator flap enables 1-block repair of extensive upper limb skin lesions. Due to limited donor-site morbidity and a pedicled technique, this resurfacing approach represents a useful tool especially in pediatric patients.

Reaction Factoring and Bipartite Update Graphs Accelerate the Gillespie Algorithm for Large-Scale Biochemical Systems

PubMed Central

Indurkhya, Sagar; Beal, Jacob

2010-01-01

ODE simulations of chemical systems perform poorly when some of the species have extremely low concentrations. Stochastic simulation methods, which can handle this case, have been impractical for large systems due to computational complexity. We observe, however, that when modeling complex biological systems: (1) a small number of reactions tend to occur a disproportionately large percentage of the time, and (2) a small number of species tend to participate in a disproportionately large percentage of reactions. We exploit these properties in LOLCAT Method, a new implementation of the Gillespie Algorithm. First, factoring reaction propensities allows many propensities dependent on a single species to be updated in a single operation. Second, representing dependencies between reactions with a bipartite graph of reactions and species requires only storage for reactions, rather than the required for a graph that includes only reactions. Together, these improvements allow our implementation of LOLCAT Method to execute orders of magnitude faster than currently existing Gillespie Algorithm variants when simulating several yeast MAPK cascade models. PMID:20066048

Analysis of multiple activity manual materials handling tasks using A Guide to Manual Materials Handling.

PubMed

Mital, A

1999-01-01

Manual handling of materials continues to be a hazardous activity, leading to a very significant number of severe overexertion injuries. Designing jobs that are within the physical capabilities of workers is one approach ergonomists have adopted to redress this problem. As a result, several job design procedures have been developed over the years. However, these procedures are limited to designing or evaluating only pure lifting jobs or only the lifting aspect of a materials handling job. This paper describes a general procedure that may be used to design or analyse materials handling jobs that involve several different kinds of activities (e.g. lifting, lowering, carrying, pushing, etc). The job design/analysis procedure utilizes an elemental approach (breaking the job into elements) and relies on databases provided in A Guide to Manual Materials Handling to compute associated risk factors. The use of the procedure is demonstrated with the help of two case studies.

Information Handling is the Problem

NASA Technical Reports Server (NTRS)

Malin, Jane T.

2001-01-01

This slide presentation reviews the concerns surrounding the automation of information handling. There are two types of decision support software that supports most Space Station Flight Controllers. one is very simple, and the other is very complex. A middle ground is sought. This is the reason for the Human Centered Autonomous and Assistant Systems Testbed (HCAAST) Project. The aim is to study flight controllers at work, and in the bigger picture, with particular attention to how they handle information and how coordination of multiple teams is performed. The focus of the project is on intelligent assistants to assist in handling information for the flight controllers.

Robotic liquid handling and automation in epigenetics.

PubMed

Gaisford, Wendy

2012-10-01

Automated liquid-handling robots and high-throughput screening (HTS) are widely used in the pharmaceutical industry for the screening of large compound libraries, small molecules for activity against disease-relevant target pathways, or proteins. HTS robots capable of low-volume dispensing reduce assay setup times and provide highly accurate and reproducible dispensing, minimizing variation between sample replicates and eliminating the potential for manual error. Low-volume automated nanoliter dispensers ensure accuracy of pipetting within volume ranges that are difficult to achieve manually. In addition, they have the ability to potentially expand the range of screening conditions from often limited amounts of valuable sample, as well as reduce the usage of expensive reagents. The ability to accurately dispense lower volumes provides the potential to achieve a greater amount of information than could be otherwise achieved using manual dispensing technology. With the emergence of the field of epigenetics, an increasing number of drug discovery companies are beginning to screen compound libraries against a range of epigenetic targets. This review discusses the potential for the use of low-volume liquid handling robots, for molecular biological applications such as quantitative PCR and epigenetics.

7 CFR 926.9 - Handle.

Code of Federal Regulations, 2013 CFR

2013-01-01

... REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.9 Handle. Handle... contract carrier of cranberries owned by another person) fresh or processed cranberries produced within or outside the United States or in any other way to place fresh or processed cranberries into the current of...

7 CFR 926.9 - Handle.

Code of Federal Regulations, 2012 CFR

2012-01-01

... REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.9 Handle. Handle... contract carrier of cranberries owned by another person) fresh or processed cranberries produced within or outside the United States or in any other way to place fresh or processed cranberries into the current of...

7 CFR 926.9 - Handle.

Code of Federal Regulations, 2011 CFR

2011-01-01

... REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.9 Handle. Handle... contract carrier of cranberries owned by another person) fresh or processed cranberries produced within or outside the United States or in any other way to place fresh or processed cranberries into the current of...

7 CFR 926.9 - Handle.

Code of Federal Regulations, 2014 CFR

2014-01-01

... REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.9 Handle. Handle... contract carrier of cranberries owned by another person) fresh or processed cranberries produced within or outside the United States or in any other way to place fresh or processed cranberries into the current of...

Irrigation mitigates against heat extremes

NASA Astrophysics Data System (ADS)

Thiery, Wim; Fischer, Erich; Visser, Auke; Hirsch, Annette L.; Davin, Edouard L.; Lawrence, Dave; Hauser, Mathias; Seneviratne, Sonia I.

2017-04-01

Irrigation is an essential practice for sustaining global food production and many regional economies. Emerging scientific evidence indicates that irrigation substantially affects mean climate conditions in different regions of the world. Yet how this practice influences climate extremes is currently unknown. Here we use gridded observations and ensemble simulations with the Community Earth System Model to assess the impacts of irrigation on climate extremes. While the influence of irrigation on annual mean temperatures is limited, we find a large impact on temperature extremes, with a particularly strong cooling during the hottest day of the year (-0.78 K averaged over irrigated land). The strong influence on hot extremes stems from the timing of irrigation and its influence on land-atmosphere coupling strength. Together these effects result in asymmetric temperature responses, with a more pronounced cooling during hot and/or dry periods. The influence of irrigation is even more pronounced when considering subgrid-scale model output, suggesting that local effects of land management are far more important than previously thought. Finally we find that present-day irrigation is partly masking GHG-induced warming of extreme temperatures, with particularly strong effects in South Asia. Our results overall underline that irrigation substantially reduces our exposure to hot temperature extremes and highlight the need to account for irrigation in future climate projections.

Uncertainty in determining extreme precipitation thresholds

NASA Astrophysics Data System (ADS)

Liu, Bingjun; Chen, Junfan; Chen, Xiaohong; Lian, Yanqing; Wu, Lili

2013-10-01

Extreme precipitation events are rare and occur mostly on a relatively small and local scale, which makes it difficult to set the thresholds for extreme precipitations in a large basin. Based on the long term daily precipitation data from 62 observation stations in the Pearl River Basin, this study has assessed the applicability of the non-parametric, parametric, and the detrended fluctuation analysis (DFA) methods in determining extreme precipitation threshold (EPT) and the certainty to EPTs from each method. Analyses from this study show the non-parametric absolute critical value method is easy to use, but unable to reflect the difference of spatial rainfall distribution. The non-parametric percentile method can account for the spatial distribution feature of precipitation, but the problem with this method is that the threshold value is sensitive to the size of rainfall data series and is subjected to the selection of a percentile thus make it difficult to determine reasonable threshold values for a large basin. The parametric method can provide the most apt description of extreme precipitations by fitting extreme precipitation distributions with probability distribution functions; however, selections of probability distribution functions, the goodness-of-fit tests, and the size of the rainfall data series can greatly affect the fitting accuracy. In contrast to the non-parametric and the parametric methods which are unable to provide information for EPTs with certainty, the DFA method although involving complicated computational processes has proven to be the most appropriate method that is able to provide a unique set of EPTs for a large basin with uneven spatio-temporal precipitation distribution. The consistency between the spatial distribution of DFA-based thresholds with the annual average precipitation, the coefficient of variation (CV), and the coefficient of skewness (CS) for the daily precipitation further proves that EPTs determined by the DFA method

Automatic liquid handling for life science: a critical review of the current state of the art.

PubMed

Kong, Fanwei; Yuan, Liang; Zheng, Yuan F; Chen, Weidong

2012-06-01

Liquid handling plays a pivotal role in life science laboratories. In experiments such as gene sequencing, protein crystallization, antibody testing, and drug screening, liquid biosamples frequently must be transferred between containers of varying sizes and/or dispensed onto substrates of varying types. The sample volumes are usually small, at the micro- or nanoliter level, and the number of transferred samples can be huge when investigating large-scope combinatorial conditions. Under these conditions, liquid handling by hand is tedious, time-consuming, and impractical. Consequently, there is a strong demand for automated liquid-handling methods such as sensor-integrated robotic systems. In this article, we survey the current state of the art in automatic liquid handling, including technologies developed by both industry and research institutions. We focus on methods for dealing with small volumes at high throughput and point out challenges for future advancements.

Spitzer SAGE-Spec: Near infrared spectroscopy, dust shells, and cool envelopes in extreme Large Magellanic Cloud asymptotic giant branch stars

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blum, R. D.; Srinivasan, S.; Kemper, F.

2014-11-01

K-band spectra are presented for a sample of 39 Spitzer Infrared Spectrograph (IRS) SAGE-Spec sources in the Large Magellanic Cloud. The spectra exhibit characteristics in very good agreement with their positions in the near-infrared—Spitzer color-magnitude diagrams and their properties as deduced from the Spitzer IRS spectra. Specifically, the near-infrared spectra show strong atomic and molecular features representative of oxygen-rich and carbon-rich asymptotic giant branch stars, respectively. A small subset of stars was chosen from the luminous and red extreme ''tip'' of the color-magnitude diagram. These objects have properties consistent with dusty envelopes but also cool, carbon-rich ''stellar'' cores. Modest amountsmore » of dust mass loss combine with the stellar spectral energy distribution to make these objects appear extreme in their near-infrared and mid-infrared colors. One object in our sample, HV 915, a known post-asymptotic giant branch star of the RV Tau type, exhibits CO 2.3 μm band head emission consistent with previous work that demonstrates that the object has a circumstellar disk.« less

7 CFR 996.4 - Handle.

Code of Federal Regulations, 2011 CFR

2011-01-01

... DOMESTIC AND IMPORTED PEANUTS MARKETED IN THE UNITED STATES Definitions § 996.4 Handle. Handle means to... imported peanuts and in the shipment (except as a common or contract carrier of peanuts owned by another) or sale of cleaned-inshell or shelled peanuts or other activity causing peanuts to enter into human...

A new approach to handling incoming verifications.

PubMed

Luizzo, Anthony; Roy, Bill; Luizzo, Philip

2016-10-01

Outside requests for data on current or former employees are handled in different ways by healthcare organizations and present considerable liability risks if a corporate policy for handling such risks is not in place. In this article, the authors present a strategy for responsible handling of sensitive information.

9 CFR 114.11 - Storage and handling.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Storage and handling. 114.11 Section... BIOLOGICAL PRODUCTS § 114.11 Storage and handling. Biological products at licensed establishments shall be protected at all times against improper storage and handling. Completed product shall be kept under...

9 CFR 114.11 - Storage and handling.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Storage and handling. 114.11 Section... BIOLOGICAL PRODUCTS § 114.11 Storage and handling. Biological products at licensed establishments shall be protected at all times against improper storage and handling. Completed product shall be kept under...

9 CFR 114.11 - Storage and handling.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Storage and handling. 114.11 Section... BIOLOGICAL PRODUCTS § 114.11 Storage and handling. Biological products at licensed establishments shall be protected at all times against improper storage and handling. Completed product shall be kept under...

14 CFR 25.489 - Ground handling conditions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Ground handling conditions. 25.489 Section... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Structure Ground Loads § 25.489 Ground handling conditions... ground handling conditions). No wing lift may be considered. The shock absorbers and tires may be assumed...

14 CFR 25.489 - Ground handling conditions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Ground handling conditions. 25.489 Section... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Structure Ground Loads § 25.489 Ground handling conditions... ground handling conditions). No wing lift may be considered. The shock absorbers and tires may be assumed...

Seasonal temperature extremes in Potsdam

NASA Astrophysics Data System (ADS)

Kundzewicz, Zbigniew; Huang, Shaochun

2010-12-01

The awareness of global warming is well established and results from the observations made on thousands of stations. This paper complements the large-scale results by examining a long time-series of high-quality temperature data from the Secular Meteorological Station in Potsdam, where observation records over the last 117 years, i.e., from January 1893 are available. Tendencies of change in seasonal temperature-related climate extremes are demonstrated. "Cold" extremes have become less frequent and less severe than in the past, while "warm" extremes have become more frequent and more severe. Moreover, the interval of the occurrence of frost has been decreasing, while the interval of the occurrence of hot days has been increasing. However, many changes are not statistically significant, since the variability of temperature indices at the Potsdam station has been very strong.

Llama handling and training.

PubMed

McGee, M

1994-07-01

This article offers insights into the relationship of llama owners to their animals and the role of veterinarians as part of the animal care team. The effect of human behavior and handling techniques on llama behavior and marketability are discussed. Progressive ideas for nonforceful llama handling equipment, procedures, and training ideas are outlined in detail. Included are specific training plans for routine herd management chores such as injections and toenail trimming. This article is useful for both veterinarians and llama owners.

Impact of an extreme climatic event on community assembly.

PubMed

Thibault, Katherine M; Brown, James H

2008-03-04

Extreme climatic events are predicted to increase in frequency and magnitude, but their ecological impacts are poorly understood. Such events are large, infrequent, stochastic perturbations that can change the outcome of entrained ecological processes. Here we show how an extreme flood event affected a desert rodent community that has been monitored for 30 years. The flood (i) caused catastrophic, species-specific mortality; (ii) eliminated the incumbency advantage of previously dominant species; (iii) reset long-term population and community trends; (iv) interacted with competitive and metapopulation dynamics; and (v) resulted in rapid, wholesale reorganization of the community. This and a previous extreme rainfall event were punctuational perturbations-they caused large, rapid population- and community-level changes that were superimposed on a background of more gradual trends driven by climate and vegetation change. Captured by chance through long-term monitoring, the impacts of such large, infrequent events provide unique insights into the processes that structure ecological communities.

Design and simulation of integration system between automated material handling system and manufacturing layout in the automotive assembly line

NASA Astrophysics Data System (ADS)

Seha, S.; Zamberi, J.; Fairu, A. J.

2017-10-01

Material handling system (MHS) is an important part for the productivity plant and has recognized as an integral part of today’s manufacturing system. Currently, MHS has growth tremendously with its technology and equipment type. Based on the case study observation, the issue involving material handling system contribute to the reduction of production efficiency. This paper aims to propose a new design of integration between material handling and manufacturing layout by investigating the influences of layout and material handling system. A method approach tool using Delmia Quest software is introduced and the simulation result is used to assess the influences of the integration between material handling system and manufacturing layout in the performance of automotive assembly line. The result show, the production of assembly line output increases more than 31% from the current system. The source throughput rate average value went up to 252 units per working hour in model 3 and show the effectiveness of the pick-to-light system as efficient storage equipment. Thus, overall result shows, the application of AGV and the pick-to-light system gave a large significant effect in the automotive assembly line. Moreover, the change of layout also shows a large significant improvement to the performance.

A large Great Britain-wide outbreak of STEC O157 phage type 8 linked to handling of raw leeks and potatoes.

PubMed

Launders, N; Locking, M E; Hanson, M; Willshaw, G; Charlett, A; Salmon, R; Cowden, J; Harker, K S; Adak, G K

2016-01-01

Between December 2010 and July 2011, 252 cases of STEC O157 PT8 stx1 + 2 infection were reported in England, Scotland and Wales. This was the largest outbreak of STEC reported in England and the second largest in the UK to date. Eighty cases were hospitalized, with two cases of haemolytic uraemic syndrome and one death reported. Routine investigative data were used to generate a hypothesis but the subsequent case-control study was inconclusive. A second, more detailed, hypothesis generation exercise identified consumption or handling of vegetables as a potential mode of transmission. A second case-control study demonstrated that cases were more likely than controls to live in households whose members handled or prepared leeks bought unwrapped [odds ratio (OR) 40, 95% confidence interval (CI) 2·08-769·4], and potatoes bought in sacks (OR 13·13, 95% CI 1·19-145·3). This appears to be the first outbreak of STEC O157 infection linked to the handling of leeks.

14 CFR 158.49 - Handling of PFC's.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Handling of PFC's. 158.49 Section 158.49... PASSENGER FACILITY CHARGES (PFC'S) Collection, Handling, and Remittance of PFC's § 158.49 Handling of PFC's... amount of PFC revenue in the covered air carrier's account at the time the bankruptcy petition is filed...

14 CFR 158.49 - Handling of PFC's.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Handling of PFC's. 158.49 Section 158.49... PASSENGER FACILITY CHARGES (PFC'S) Collection, Handling, and Remittance of PFC's § 158.49 Handling of PFC's... amount of PFC revenue in the covered air carrier's account at the time the bankruptcy petition is filed...

14 CFR 158.49 - Handling of PFC's.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Handling of PFC's. 158.49 Section 158.49... PASSENGER FACILITY CHARGES (PFC'S) Collection, Handling, and Remittance of PFC's § 158.49 Handling of PFC's... amount of PFC revenue in the covered air carrier's account at the time the bankruptcy petition is filed...

14 CFR 158.49 - Handling of PFC's.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Handling of PFC's. 158.49 Section 158.49... PASSENGER FACILITY CHARGES (PFC'S) Collection, Handling, and Remittance of PFC's § 158.49 Handling of PFC's... amount of PFC revenue in the covered air carrier's account at the time the bankruptcy petition is filed...

14 CFR 158.49 - Handling of PFC's.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Handling of PFC's. 158.49 Section 158.49... PASSENGER FACILITY CHARGES (PFC'S) Collection, Handling, and Remittance of PFC's § 158.49 Handling of PFC's... amount of PFC revenue in the covered air carrier's account at the time the bankruptcy petition is filed...

Ground data handling for LANDSAT-D

NASA Technical Reports Server (NTRS)

Lynch, T. J.

1976-01-01

The present plans for the LANDSAT D ground data handling are described in relationship to the mission objectives and the planned spacecraft system. The end to end data system is presented with particular emphasis on the data handling plans for the new instrument, the Thematic Mapper. This instrument generates ten times the amount of data per scene as the present Multispectral Scanner, and this resulting data rate and volume are discussed as well as possible new data techniques to handle them such as image compression.

Tethered particle analysis of supercoiled circular DNA using peptide nucleic acid handles.

PubMed

Norregaard, Kamilla; Andersson, Magnus; Nielsen, Peter Eigil; Brown, Stanley; Oddershede, Lene B

2014-09-01

This protocol describes how to monitor individual naturally supercoiled circular DNA plasmids bound via peptide nucleic acid (PNA) handles between a bead and a surface. The protocol was developed for single-molecule investigation of the dynamics of supercoiled DNA, and it allows the investigation of both the dynamics of the molecule itself and of its interactions with a regulatory protein. Two bis-PNA clamps designed to bind with extremely high affinity to predetermined homopurine sequence sites in supercoiled DNA are prepared: one conjugated with digoxigenin for attachment to an anti-digoxigenin-coated glass cover slide, and one conjugated with biotin for attachment to a submicron-sized streptavidin-coated polystyrene bead. Plasmids are constructed, purified and incubated with the PNA handles. The dynamics of the construct is analyzed by tracking the tethered bead using video microscopy: less supercoiling results in more movement, and more supercoiling results in less movement. In contrast to other single-molecule methodologies, the current methodology allows for studying DNA in its naturally supercoiled state with constant linking number and constant writhe. The protocol has potential for use in studying the influence of supercoils on the dynamics of DNA and its associated proteins, e.g., topoisomerase. The procedure takes ~4 weeks.

The role of Natural Flood Management in managing floods in large scale basins during extreme events

NASA Astrophysics Data System (ADS)

Quinn, Paul; Owen, Gareth; ODonnell, Greg; Nicholson, Alex; Hetherington, David

2016-04-01

There is a strong evidence database showing the negative impacts of land use intensification and soil degradation in NW European river basins on hydrological response and to flood impact downstream. However, the ability to target zones of high runoff production and the extent to which we can manage flood risk using nature-based flood management solution are less known. A move to planting more trees and having less intense farmed landscapes is part of natural flood management (NFM) solutions and these methods suggest that flood risk can be managed in alternative and more holistic ways. So what local NFM management methods should be used, where in large scale basin should they be deployed and how does flow is propagate to any point downstream? Generally, how much intervention is needed and will it compromise food production systems? If we are observing record levels of rainfall and flow, for example during Storm Desmond in Dec 2015 in the North West of England, what other flood management options are really needed to complement our traditional defences in large basins for the future? In this paper we will show examples of NFM interventions in the UK that have impacted at local scale sites. We will demonstrate the impact of interventions at local, sub-catchment (meso-scale) and finally at the large scale. These tools include observations, process based models and more generalised Flood Impact Models. Issues of synchronisation and the design level of protection will be debated. By reworking observed rainfall and discharge (runoff) for observed extreme events in the River Eden and River Tyne, during Storm Desmond, we will show how much flood protection is needed in large scale basins. The research will thus pose a number of key questions as to how floods may have to be managed in large scale basins in the future. We will seek to support a method of catchment systems engineering that holds water back across the whole landscape as a major opportunity to management water

Rotorcraft handling-qualities design criteria development

NASA Technical Reports Server (NTRS)

Aiken, Edwin W.; Lebacqz, J. Victor; Chen, Robert T. N.; Key, David L.

1988-01-01

Joint NASA/Army efforts at the Ames Research Center to develop rotorcraft handling-qualities design criteria began in earnest in 1975. Notable results were the UH-1H VSTOLAND variable stability helicopter, the VFA-2 camera-and-terrain-board simulator visual system, and the generic helicopter real-time mathematical model, ARMCOP. An initial series of handling-qualities studies was conducted to assess the effects of rotor design parameters, interaxis coupling, and various levels of stability and control augmentation. The ability to conduct in-flight handling-qualities research was enhanced by the development of the NASA/Army CH-47 variable-stability helicopter. Research programs conducted using this vehicle include vertical-response investigations, hover augmentation systems, and the effects of control-force characteristics. The handling-qualities data base was judged to be sufficient to allow an update of the military helicopter handling-qualities specification, MIL-H-8501. These efforts, including not only the in-house experimental work but also contracted research and collaborative programs performed under the auspices of various international agreements. The report concludes by reviewing the topics that are currently most in need of work, and the plans for addressing these topics.

Ergonomics: safe patient handling and mobility.

PubMed

Hallmark, Beth; Mechan, Patricia; Shores, Lynne

2015-03-01

This article reviews and investigates the issues surrounding ergonomics, with a specific focus on safe patient handling and mobility. The health care worker of today faces many challenges, one of which is related to the safety of patients. Safe patient handling and mobility is on the forefront of the movement to improve patient safety. This article reviews the risks associated with patient handling and mobility, and informs the reader of current evidence-based practice relevant to this area of care. Copyright © 2015 Elsevier Inc. All rights reserved.

Flood protection diversification to reduce probabilities of extreme losses.

PubMed

Zhou, Qian; Lambert, James H; Karvetski, Christopher W; Keisler, Jeffrey M; Linkov, Igor

2012-11-01

Recent catastrophic losses because of floods require developing resilient approaches to flood risk protection. This article assesses how diversification of a system of coastal protections might decrease the probabilities of extreme flood losses. The study compares the performance of portfolios each consisting of four types of flood protection assets in a large region of dike rings. A parametric analysis suggests conditions in which diversifications of the types of included flood protection assets decrease extreme flood losses. Increased return periods of extreme losses are associated with portfolios where the asset types have low correlations of economic risk. The effort highlights the importance of understanding correlations across asset types in planning for large-scale flood protection. It allows explicit integration of climate change scenarios in developing flood mitigation strategy. © 2012 Society for Risk Analysis.

Exception handling for sensor fusion

NASA Astrophysics Data System (ADS)

Chavez, G. T.; Murphy, Robin R.

1993-08-01

This paper presents a control scheme for handling sensing failures (sensor malfunctions, significant degradations in performance due to changes in the environment, and errant expectations) in sensor fusion for autonomous mobile robots. The advantages of the exception handling mechanism are that it emphasizes a fast response to sensing failures, is able to use only a partial causal model of sensing failure, and leads to a graceful degradation of sensing if the sensing failure cannot be compensated for. The exception handling mechanism consists of two modules: error classification and error recovery. The error classification module in the exception handler attempts to classify the type and source(s) of the error using a modified generate-and-test procedure. If the source of the error is isolated, the error recovery module examines its cache of recovery schemes, which either repair or replace the current sensing configuration. If the failure is due to an error in expectation or cannot be identified, the planner is alerted. Experiments using actual sensor data collected by the CSM Mobile Robotics/Machine Perception Laboratory's Denning mobile robot demonstrate the operation of the exception handling mechanism.

Differences among nursing homes in outcomes of a safe resident handling program

PubMed Central

Kurotvski, Alicia; Gore, Rebecca; Buchholz, Bryan; Punnett, Laura

2018-01-01

A large nursing home corporation implemented a safe resident handling program (SRHP) in 2004–2007. We evaluated its efficacy over a 2-year period by examining differences among 5 centers in program outcomes and potential predictors of those differences. We observed nursing assistants (NAs), recording activities and body postures at 60-second intervals on personal digital assistants at baseline and at 3-month, 12-month, and 24-month follow-ups. The two outcomes computed were change in equipment use during resident handling and change in a physical workload index that estimated spinal loading due to body postures and handled loads. Potential explanatory factors were extracted from post-observation interviews, investigator surveys of the workforce, from administrative data, and employee satisfaction surveys. The facility with the most positive outcome measures was associated with many positive changes in explanatory factors and the facility with the fewest positive outcome measures experienced negative changes in the same factors. These findings suggest greater SRHP benefits where there was lower NA turnover and agency staffing; less time pressure; and better teamwork, staff communication, and supervisory support. PMID:22833329

Apodized Pupil Lyot Coronagraphs for Arbitrary Apertures. II. Theoretical Properties and Application to Extremely Large Telescopes

NASA Astrophysics Data System (ADS)

Soummer, Rémi; Pueyo, Laurent; Ferrari, André; Aime, Claude; Sivaramakrishnan, Anand; Yaitskova, Natalia

2009-04-01

We study the application of Lyot coronagraphy to future Extremely Large Telescopes (ELTs), showing that Apodized Pupil Lyot Coronagraphs enable high-contrast imaging for exoplanet detection and characterization with ELTs. We discuss the properties of the optimal pupil apodizers for this application (generalized prolate spheroidal functions). The case of a circular aperture telescope with a central obstruction is considered in detail, and we discuss the effects of primary mirror segmentation and secondary mirror support structures as a function of the occulting mask size. In most cases where inner working distance is critical, e.g., for exoplanet detection, these additional features do not alter the solutions derived with just the central obstruction, although certain applications such as quasar-host galaxy coronagraphic observations could benefit from designs that explicitly accomodate ELT spider geometries. We illustrate coronagraphic designs for several ELT geometries including ESO/OWL, the Thirty Mirror Telescope, the Giant Magellan Telescope, and describe numerical methods for generating these designs.

Extreme Weather and Climate: Workshop Report

NASA Technical Reports Server (NTRS)

Sobel, Adam; Camargo, Suzana; Debucquoy, Wim; Deodatis, George; Gerrard, Michael; Hall, Timothy; Hallman, Robert; Keenan, Jesse; Lall, Upmanu; Levy, Marc;

Contribution of large-scale circulation anomalies to changes in extreme precipitation frequency in the United States

Treesearch

Lejiang Yu; Shiyuan Zhong; Lisi Pei; Xindi (Randy) Bian; Warren E. Heilman

2016-01-01

The mean global climate has warmed as a result of the increasing emission of greenhouse gases induced by human activities. This warming is considered the main reason for the increasing number of extreme precipitation events in the US. While much attention has been given to extreme precipitation events occurring over several days, which are usually responsible for...

Reducing variation in a rabbit vaccine safety study with particular emphasis on housing conditions and handling.

PubMed

Verwer, Cynthia M; van der Ark, Arno; van Amerongen, Geert; van den Bos, Ruud; Hendriksen, Coenraad F M

2009-04-01

This paper describes the results of a study of the effects of modified housing conditions, conditioning and habituation on humans using a rabbit model for monitoring whole-cell pertussis vaccine (pWCV)-induced adverse effects. The study has been performed with reference to previous vaccine safety studies of pWCV in rabbits in which results were difficult to interpret due to the large variation in experimental outcome, especially in the key parameter deep-body temperature (T(b)). Certain stressful laboratory conditions, as well as procedures involving humans, e.g. blood sampling, inoculation and cage-cleaning, were hypothesized to cause this large variation. The results of this study show that under modified housing conditions rabbits have normal circadian body temperatures. This allowed discrimination of pWCV-induced adverse effects in which handled rabbits tended to show a dose-related increase in temperature after inoculation with little variance, whereas non-handled rabbits did not. Effects of experimental and routine procedures on body temperature were significantly reduced under modified conditions and were within the normal T(b) range. Handled animals reacted less strongly and with less variance to experimental procedures, such as blood sampling, injection and cage-cleaning, than non-handled rabbits. Overall, handling had a positive effect on the behaviour of the animals. Data show that the housing modifications have provided a more robust model for monitoring pWCV adverse effects. Furthermore, conditioning and habituation of rabbits to humans reduce the variation in experimental outcome, which might allow for a reduction in the number of animals used. In addition, this also reduces distress and thus contributes to refining this animal model.

Role of absorbing aerosols on hot extremes in India in a GCM

NASA Astrophysics Data System (ADS)

Mondal, A.; Sah, N.; Venkataraman, C.; Patil, N.

2017-12-01

Temperature extremes and heat waves in North-Central India during the summer months of March through June are known for causing significant impact in terms of human health, productivity and mortality. While greenhouse gas-induced global warming is generally believed to intensify the magnitude and frequency of such extremes, aerosols are usually associated with an overall cooling, by virtue of their dominant radiation scattering nature, in most world regions. Recently, large-scale atmospheric conditions leading to heat wave and extreme temperature conditions have been analysed for the North-Central Indian region. However, the role of absorbing aerosols, including black carbon and dust, is still not well understood, in mediating hot extremes in the region. In this study, we use 30-year simulations from a chemistry-coupled atmosphere-only General Circulation Model (GCM), ECHAM6-HAM2, forced with evolving aerosol emissions in an interactive aerosol module, along with observed sea surface temperatures, to examine large-scale and mesoscale conditions during hot extremes in India. The model is first validated with observed gridded temperature and reanalysis data, and is found to represent observed variations in temperature in the North-Central region and concurrent large-scale atmospheric conditions during high temperature extremes realistically. During these extreme events, changes in near surface properties include a reduction in single scattering albedo and enhancement in short-wave solar heating rate, compared to climatological conditions. This is accompanied by positive anomalies of black carbon and dust aerosol optical depths. We conclude that the large-scale atmospheric conditions such as the presence of anticyclones and clear skies, conducive to heat waves and high temperature extremes, are exacerbated by absorbing aerosols in North-Central India. Future air quality regulations are expected to reduce sulfate particles and their masking of GHG warming. It is

Countering Insider Threats - Handling Insider Threats Using Dynamic, Run-Time Forensics

DTIC Science & Technology

2007-10-01

able to handle the security policy requirements of a large organization containing many decentralized and diverse users, while being easily managed... contained in the TIF folder. Searching for any text string and sorting is supported also. The cache index file of Internet Explorer is not changed... containing thousands of malware software signatures. Separate datasets can be created for various classifications of malware such as encryption software

Large Scale Landslide Database System Established for the Reservoirs in Southern Taiwan

NASA Astrophysics Data System (ADS)

Tsai, Tsai-Tsung; Tsai, Kuang-Jung; Shieh, Chjeng-Lun

2017-04-01

Typhoon Morakot seriously attack southern Taiwan awaken the public awareness of large scale landslide disasters. Large scale landslide disasters produce large quantity of sediment due to negative effects on the operating functions of reservoirs. In order to reduce the risk of these disasters within the study area, the establishment of a database for hazard mitigation / disaster prevention is necessary. Real time data and numerous archives of engineering data, environment information, photo, and video, will not only help people make appropriate decisions, but also bring the biggest concern for people to process and value added. The study tried to define some basic data formats / standards from collected various types of data about these reservoirs and then provide a management platform based on these formats / standards. Meanwhile, in order to satisfy the practicality and convenience, the large scale landslide disasters database system is built both provide and receive information abilities, which user can use this large scale landslide disasters database system on different type of devices. IT technology progressed extreme quick, the most modern system might be out of date anytime. In order to provide long term service, the system reserved the possibility of user define data format /standard and user define system structure. The system established by this study was based on HTML5 standard language, and use the responsive web design technology. This will make user can easily handle and develop this large scale landslide disasters database system.

The effect of ergonomic laparoscopic tool handle design on performance and efficiency.

PubMed

Tung, Kryztopher D; Shorti, Rami M; Downey, Earl C; Bloswick, Donald S; Merryweather, Andrew S

2015-09-01

Many factors can affect a surgeon's performance in the operating room; these may include surgeon comfort, ergonomics of tool handle design, and fatigue. A laparoscopic tool handle designed with ergonomic considerations (pistol grip) was tested against a current market tool with a traditional pinch grip handle. The goal of this study is to quantify the impact ergonomic design considerations which have on surgeon performance. We hypothesized that there will be measurable differences between the efficiency while performing FLS surgical trainer tasks when using both tool handle designs in three categories: time to completion, technical skill, and subjective user ratings. The pistol grip incorporates an ergonomic interface intended to reduce contact stress points on the hand and fingers, promote a more neutral operating wrist posture, and reduce hand tremor and fatigue. The traditional pinch grip is a laparoscopic tool developed by Stryker Inc. widely used during minimal invasive surgery. Twenty-three (13 M, 10 F) participants with no existing upper extremity musculoskeletal disorders or experience performing laparoscopic procedures were selected to perform in this study. During a training session prior to testing, participants performed practice trials in a SAGES FLS trainer with both tools. During data collection, participants performed three evaluation tasks using both handle designs (order was randomized, and each trial completed three times). The tasks consisted of FLS peg transfer, cutting, and suturing tasks. Feedback from test participants indicated that they significantly preferred the ergonomic pistol grip in every category (p < 0.05); most notably, participants experienced greater degrees of discomfort in their hands after using the pinch grip tool. Furthermore, participants completed cutting and peg transfer tasks in a shorter time duration (p < 0.05) with the pistol grip than with the pinch grip design; there was no significant difference between completion

SITE GENERATED RADIOLOGICAL WASTE HANDLING SYSTEM DESCRIPTION DOCUMENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

S. C. Khamankar

2000-06-20

The Site Generated Radiological Waste Handling System handles radioactive waste products that are generated at the geologic repository operations area. The waste is collected, treated if required, packaged for shipment, and shipped to a disposal site. Waste streams include low-level waste (LLW) in solid and liquid forms, as-well-as mixed waste that contains hazardous and radioactive constituents. Liquid LLW is segregated into two streams, non-recyclable and recyclable. The non-recyclable stream may contain detergents or other non-hazardous cleaning agents and is packaged for shipment. The recyclable stream is treated to recycle a large portion of the water while the remaining concentrated wastemore » is packaged for shipment; this greatly reduces the volume of waste requiring disposal. There will be no liquid LLW discharge. Solid LLW consists of wet solids such as ion exchange resins and filter cartridges, as-well-as dry active waste such as tools, protective clothing, and poly bags. Solids will be sorted, volume reduced, and packaged for shipment. The generation of mixed waste at the Monitored Geologic Repository (MGR) is not planned; however, if it does come into existence, it will be collected and packaged for disposal at its point of occurrence, temporarily staged, then shipped to government-approved off-site facilities for disposal. The Site Generated Radiological Waste Handling System has equipment located in both the Waste Treatment Building (WTB) and in the Waste Handling Building (WHB). All types of liquid and solid LLW are processed in the WTB, while wet solid waste from the Pool Water Treatment and Cooling System is packaged where received in the WHB. There is no installed hardware for mixed waste. The Site Generated Radiological Waste Handling System receives waste from locations where water is used for decontamination functions. In most cases the water is piped back to the WTB for processing. The WTB and WHB provide staging areas for storing and

Cost of Information Handling in Hospitals

PubMed Central

Jydstrup, Ronald A.; Gross, Malvern J.

1966-01-01

Cost of information handling (noncomputerized) in hospitals was studied in detail from an industrial engineering point of view at Rochester General, Highland, and Geneva General hospitals. Activities were observed, personnel questioned, and time studies carried out. It was found that information handling comprises about one fourth of the hospitals' operating cost—a finding strongly recommending revision and streamlining of both forms and inefficient operations. In an Appendix to this study are presented 15 items that would improve information handling in one area of the hospital, nursing units, where this activity is greater than in any other in a hospital. PMID:5971636

Extremely large telescopes as a motor of socio-economic development and implications of their construction and installation

NASA Astrophysics Data System (ADS)

Burgos-Martin, J.; Sanchez-Padron, M.; Sanchez, F.; Martinez-Roger, Carlos

2004-07-01

Large-Scale observing facilities are scarce and costly. Even so, the perspective to enlarge or to increase the number of these facilities are quite real and several projects are undertaking their first steps in this direction. These costly facilities require the cooperation of highly qualified institutions, able to undertake the project from the scientific and technological point of view, as well as the vital collaboration and effective support of several countries, at the highest level, able to provide the necessary investment for their construction. Because of these technological implications and the financial magnitude of these projects, their impact goes well beyond the international astrophysical community. We propose to carry out a study on the socio-economic impact from the construction and operation of an Extremely Large Telescope of class 30 - 100 m. We plan to approach several aspects such as its impact in the promotion of the employment; social, educational and cultural integration of the population; the impulse of industries; its impact on the national and international policies on research; environmental issues; etc. We will also analyze the financial instruments available, and those special aids only accessible for some countries and regions to encourage their participation in projects of this magnitude.

Early handling modulates outcome of neonatal dexamethasone exposure.

PubMed

Claessens, Sanne E F; Daskalakis, Nikolaos P; Oitzl, Melly S; de Kloet, E Ronald

2012-09-01

Synthetic glucocorticoids such as dexamethasone (DEX) are used to prevent or treat respiratory disorders in prematurely born infants. Besides the short-term benefit on lung development, numerous human and animal studies have reported adverse neurodevelopmental side effects. In contrast, maternal care is known to exert a positive influence on neurodevelopmental outcome in rodents. The aim of the current study was therefore to investigate whether neonatal handling (days 1-21), known to induce maternal care, might serve as an intervention strategy modulating the adverse effects of DEX treatment (days 1-3). For this purpose we have measured the outcome of these early-life manipulations on development as well as adult endocrine and behavioral phenotype of male rats. Maternal care was observed during the first week of life and indeed enhanced in response to handling. Eye opening was accelerated and body weight reduced in DEX-treated animals. In adulthood, we report that handling ameliorated impaired spatial learning observed in DEX treated non-handled animals in the T-maze. Additionally, handling reduced susceptibility to the impact of DEX treatment in the water maze. Although DEX treatment and handling both resulted in enhanced negative feedback of the stress-induced corticosterone response and both reduced startle reactivity, the acquisition of fear was only reduced by handling, without effect of DEX. Interestingly, handling had a beneficial effect on pre-pulse inhibition, which was diminished after DEX treatment. In conclusion, these findings indicate that handling of the neonate enhances maternal care and attenuates specific DEX-induced alterations in the adult behavioral phenotype. Copyright © 2012 Elsevier Inc. All rights reserved.

30 CFR 75.833 - Handling high-voltage trailing cables.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Handling high-voltage trailing cables. 75.833... High-Voltage Longwalls § 75.833 Handling high-voltage trailing cables. (a) Cable handling. (1) Miners must not handle energized trailing cables unless they are wearing high-voltage insulating gloves, which...

Evaluation of dynamically downscaled extreme temperature using a spatially-aggregated generalized extreme value (GEV) model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Jiali; Han, Yuefeng; Stein, Michael L.

2016-02-10

The Weather Research and Forecast (WRF) model downscaling skill in extreme maximum daily temperature is evaluated by using the generalized extreme value (GEV) distribution. While the GEV distribution has been used extensively in climatology and meteorology for estimating probabilities of extreme events, accurately estimating GEV parameters based on data from a single pixel can be difficult, even with fairly long data records. This work proposes a simple method assuming that the shape parameter, the most difficult of the three parameters to estimate, does not vary over a relatively large region. This approach is applied to evaluate 31-year WRF-downscaled extreme maximummore » temperature through comparison with North American Regional Reanalysis (NARR) data. Uncertainty in GEV parameter estimates and the statistical significance in the differences of estimates between WRF and NARR are accounted for by conducting bootstrap resampling. Despite certain biases over parts of the United States, overall, WRF shows good agreement with NARR in the spatial pattern and magnitudes of GEV parameter estimates. Both WRF and NARR show a significant increase in extreme maximum temperature over the southern Great Plains and southeastern United States in January and over the western United States in July. The GEV model shows clear benefits from the regionally constant shape parameter assumption, for example, leading to estimates of the location and scale parameters of the model that show coherent spatial patterns.« less

Airborne microorganisms associated with grain handling.

PubMed

Swan, J R; Crook, B

1998-01-01

There is substantial evidence that workers handling grain develop allergic respiratory symptoms. Microbiological contaminants are likely to be a significant contributing factor. Worker's exposure to microorganisms contaminating grain dust in the UK was therefore examined. Aerobiological studies were made when grain was being handled on farms and also during bulk handling of grain in dockside terminals. A quantitative and qualitative microbiological examination of the airborne grain dust was carried out. Samples of airborne grain dust were collected and viable bacteria, fungi and actinomycetes were grown, isolated and identified. It was found that workers handling grain or working close to grain at farms and docks were frequently exposed to more than 1 million bacteria and fungi per m3 air, and that airborne bacteria and fungi exceeded 10(4) per m3 air in all areas sampled. The qualitative examination of the samples showed that the predominant microorganisms present differed between freshly harvested grain and stored grain, but not between different types of grain.

Human Handling Promotes Compliant Behavior in Adult Laboratory Rabbits

PubMed Central

Swennes, Alton G; Alworth, Leanne C; Harvey, Stephen B; Jones, Carolyn A; King, Christopher S; Crowell-Davis, Sharon L

2011-01-01

Routine laboratory procedures can be stressful for laboratory animals. We wanted to determine whether human handling of adult rabbits could induce a degree of habituation, reducing stress and facilitating research-related manipulation. To this end, adult New Zealand white rabbits were handled either frequently or minimally. After being handled over 3 wk, these rabbits were evaluated by novel personnel and compared with minimally handled controls. Evaluators subjectively scored the rabbits for their relative compliance or resistance to being scruffed and removed from their cages, being transported to a treatment room, and their behavior at all stages of the exercise. Upon evaluation, handled rabbits scored significantly more compliant than nontreated controls. During evaluation, behaviors that the rabbits displayed when they were approached in their cages and while being handled outside their cages were recorded and compared between study groups. Handled rabbits displayed behavior consistent with a reduction in human-directed fear. This study illustrates the potential for handling to improve compliance in laboratory procedures and reduce fear-related behavior in laboratory rabbits. Such handling could be used to improve rabbit welfare through the reduction of stress and exposure to novel stimuli. PMID:21333162

Climate signature of Northwest U.S. precipitation Extremes

NASA Astrophysics Data System (ADS)

Kushnir, Y.; Nakamura, J.

2017-12-01

The climate signature of precipitation extremes in the Northwest U.S. - the region that includes Oregon, Washington, Idaho, Montana and Wyoming - is studied using composite analysis of atmospheric fields leading to and associated with extreme rainfall events. A K-Medoids cluster analysis is applied to winter (November-February) months, maximum 5-day precipitation amounts calculated from 1-degree gridded daily rainfall between 1950/51 and 2013/14. The clustering divides the region into three sub-regions: one over the far eastern part of the analysis domain, includeing most of Montana and Wyoming. Two other sub-regions are in the west, lying north and south of the latitude of 45N. Using the time series corresponding to the Medoid centers, we extract the largest (top 5%) monthly extreme events to form the basis for the composite analysis. The main circulation feature distinguishing a 5-day extreme precipitation event in the two western sub-regions of the Northwest is the presence of a large, blocking, high pressure anomaly over the Gulf of Alaska about a week before the beginning of the 5-day intense precipitation event. The high pressure center intensifies considerably with time, drifting slowly westward, up to a day before the extreme event. During that time, a weak low pressure centers appears at 30N, to the southwest of the high, deepening as it moves east. As the extreme rainfall event is about to begin, the now deep low is encroaching on the Northwest coast while its southern flank taps well south into the subtropical Pacific, drawing moisture from as south as 15N. During the 5-day extreme precipitation event the high pressure center moves west and weakens while the now intense low converges large amounts of subtropical moisture to precipitate over the western Northwest. The implication of this analysis for extended range prediction is assessed.

Extreme weather: Subtropical floods and tropical cyclones

NASA Astrophysics Data System (ADS)

Shaevitz, Daniel A.

Extreme weather events have a large effect on society. As such, it is important to understand these events and to project how they may change in a future, warmer climate. The aim of this thesis is to develop a deeper understanding of two types of extreme weather events: subtropical floods and tropical cyclones (TCs). In the subtropics, the latitude is high enough that quasi-geostrophic dynamics are at least qualitatively relevant, while low enough that moisture may be abundant and convection strong. Extratropical extreme precipitation events are usually associated with large-scale flow disturbances, strong ascent, and large latent heat release. In the first part of this thesis, I examine the possible triggering of convection by the large-scale dynamics and investigate the coupling between the two. Specifically two examples of extreme precipitation events in the subtropics are analyzed, the 2010 and 2014 floods of India and Pakistan and the 2015 flood of Texas and Oklahoma. I invert the quasi-geostrophic omega equation to decompose the large-scale vertical motion profile to components due to synoptic forcing and diabatic heating. Additionally, I present model results from within the Column Quasi-Geostrophic framework. A single column model and cloud-revolving model are forced with the large-scale forcings (other than large-scale vertical motion) computed from the quasi-geostrophic omega equation with input data from a reanalysis data set, and the large-scale vertical motion is diagnosed interactively with the simulated convection. It is found that convection was triggered primarily by mechanically forced orographic ascent over the Himalayas during the India/Pakistan flood and by upper-level Potential Vorticity disturbances during the Texas/Oklahoma flood. Furthermore, a climate attribution analysis was conducted for the Texas/Oklahoma flood and it is found that anthropogenic climate change was responsible for a small amount of rainfall during the event but the

Handling of thermal paper: Implications for dermal exposure to bisphenol A and its alternatives

PubMed Central

Bernier, Meghan R.

2017-01-01

Bisphenol A (BPA) is an endocrine disrupting chemical used in a wide range of consumer products including photoactive dyes used in thermal paper. Recent studies have shown that dermal absorption of BPA can occur when handling these papers. Yet, regulatory agencies have largely dismissed thermal paper as a major source of BPA exposure. Exposure estimates provided by agencies such as the European Food Safety Authority (EFSA) are based on assumptions about how humans interact with this material, stating that ‘typical’ exposures for adults involve only one handling per day for short periods of time (<1 minute), with limited exposure surfaces (three fingertips). The objective of this study was to determine how individuals handle thermal paper in one common setting: a cafeteria providing short-order meals. We observed thermal paper handling in a college-aged population (n = 698 subjects) at the University of Massachusetts’ dining facility. We find that in this setting, individuals handle receipts for an average of 11.5 min, that >30% of individuals hold thermal paper with more than three fingertips, and >60% allow the paper to touch their palm. Only 11% of the participants we observed were consistent with the EFSA model for time of contact and dermal surface area. Mathematical modeling based on handling times we measured and previously published transfer coefficients, concentrations of BPA in paper, and absorption factors indicate the most conservative estimated intake from handling thermal paper in this population is 51.1 ng/kg/day, similar to EFSA’s estimates of 59 ng/kg/day from dermal exposures. Less conservative estimates, using published data on concentrations in thermal paper and transfer rates to skin, indicate that exposures are likely significantly higher. Based on our observational data, we propose that the current models for estimating dermal BPA exposures are not consistent with normal human behavior and should be reevaluated. PMID:28570582

Handling of thermal paper: Implications for dermal exposure to bisphenol A and its alternatives.

PubMed

Bernier, Meghan R; Vandenberg, Laura N

2017-01-01

Bisphenol A (BPA) is an endocrine disrupting chemical used in a wide range of consumer products including photoactive dyes used in thermal paper. Recent studies have shown that dermal absorption of BPA can occur when handling these papers. Yet, regulatory agencies have largely dismissed thermal paper as a major source of BPA exposure. Exposure estimates provided by agencies such as the European Food Safety Authority (EFSA) are based on assumptions about how humans interact with this material, stating that 'typical' exposures for adults involve only one handling per day for short periods of time (<1 minute), with limited exposure surfaces (three fingertips). The objective of this study was to determine how individuals handle thermal paper in one common setting: a cafeteria providing short-order meals. We observed thermal paper handling in a college-aged population (n = 698 subjects) at the University of Massachusetts' dining facility. We find that in this setting, individuals handle receipts for an average of 11.5 min, that >30% of individuals hold thermal paper with more than three fingertips, and >60% allow the paper to touch their palm. Only 11% of the participants we observed were consistent with the EFSA model for time of contact and dermal surface area. Mathematical modeling based on handling times we measured and previously published transfer coefficients, concentrations of BPA in paper, and absorption factors indicate the most conservative estimated intake from handling thermal paper in this population is 51.1 ng/kg/day, similar to EFSA's estimates of 59 ng/kg/day from dermal exposures. Less conservative estimates, using published data on concentrations in thermal paper and transfer rates to skin, indicate that exposures are likely significantly higher. Based on our observational data, we propose that the current models for estimating dermal BPA exposures are not consistent with normal human behavior and should be reevaluated.

7 CFR 959.53 - Handling for special purposes.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Handling for special purposes. 959.53 Section 959.53 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Regulating Handling Regulations § 959.53 Handling for special purposes. Regulations in effect pursuant to...

Handling Qualities Optimization for Rotorcraft Conceptual Design

NASA Technical Reports Server (NTRS)

Lawrence, Ben; Theodore, Colin R.; Berger, Tom

2016-01-01

Over the past decade, NASA, under a succession of rotary-wing programs has been moving towards coupling multiple discipline analyses in a rigorous consistent manner to evaluate rotorcraft conceptual designs. Handling qualities is one of the component analyses to be included in a future NASA Multidisciplinary Analysis and Optimization framework for conceptual design of VTOL aircraft. Similarly, the future vision for the capability of the Concept Design and Assessment Technology Area (CD&A-TA) of the U.S Army Aviation Development Directorate also includes a handling qualities component. SIMPLI-FLYD is a tool jointly developed by NASA and the U.S. Army to perform modeling and analysis for the assessment of flight dynamics and control aspects of the handling qualities of rotorcraft conceptual designs. An exploration of handling qualities analysis has been carried out using SIMPLI-FLYD in illustrative scenarios of a tiltrotor in forward flight and single-main rotor helicopter at hover. Using SIMPLI-FLYD and the conceptual design tool NDARC integrated into a single process, the effects of variations of design parameters such as tail or rotor size were evaluated in the form of margins to fixed- and rotary-wing handling qualities metrics as well as the vehicle empty weight. The handling qualities design margins are shown to vary across the flight envelope due to both changing flight dynamic and control characteristics and changing handling qualities specification requirements. The current SIMPLI-FLYD capability and future developments are discussed in the context of an overall rotorcraft conceptual design process.

A general method for handling missing binary outcome data in randomized controlled trials.

PubMed

Jackson, Dan; White, Ian R; Mason, Dan; Sutton, Stephen

2014-12-01

The analysis of randomized controlled trials with incomplete binary outcome data is challenging. We develop a general method for exploring the impact of missing data in such trials, with a focus on abstinence outcomes. We propose a sensitivity analysis where standard analyses, which could include 'missing = smoking' and 'last observation carried forward', are embedded in a wider class of models. We apply our general method to data from two smoking cessation trials. A total of 489 and 1758 participants from two smoking cessation trials. The abstinence outcomes were obtained using telephone interviews. The estimated intervention effects from both trials depend on the sensitivity parameters used. The findings differ considerably in magnitude and statistical significance under quite extreme assumptions about the missing data, but are reasonably consistent under more moderate assumptions. A new method for undertaking sensitivity analyses when handling missing data in trials with binary outcomes allows a wide range of assumptions about the missing data to be assessed. In two smoking cessation trials the results were insensitive to all but extreme assumptions. © 2014 The Authors. Addiction published by John Wiley & Sons Ltd on behalf of Society for the Study of Addiction.

A general method for handling missing binary outcome data in randomized controlled trials

PubMed Central

Jackson, Dan; White, Ian R; Mason, Dan; Sutton, Stephen

2014-01-01

Aims The analysis of randomized controlled trials with incomplete binary outcome data is challenging. We develop a general method for exploring the impact of missing data in such trials, with a focus on abstinence outcomes. Design We propose a sensitivity analysis where standard analyses, which could include ‘missing = smoking’ and ‘last observation carried forward’, are embedded in a wider class of models. Setting We apply our general method to data from two smoking cessation trials. Participants A total of 489 and 1758 participants from two smoking cessation trials. Measurements The abstinence outcomes were obtained using telephone interviews. Findings The estimated intervention effects from both trials depend on the sensitivity parameters used. The findings differ considerably in magnitude and statistical significance under quite extreme assumptions about the missing data, but are reasonably consistent under more moderate assumptions. Conclusions A new method for undertaking sensitivity analyses when handling missing data in trials with binary outcomes allows a wide range of assumptions about the missing data to be assessed. In two smoking cessation trials the results were insensitive to all but extreme assumptions. PMID:25171441

Parallax handling of image stitching using dominant-plane homography

NASA Astrophysics Data System (ADS)

Pang, Zhaofeng; Li, Cheng; Zhao, Baojun; Tang, Linbo

2015-10-01

In this paper, we present a novel image stitching method to handle parallax in practical application. For images with significant amount of parallax, the more effective approach is to align roughly and globally the overlapping regions and then apply a seam-cutting method to composite naturally stitched images. It is well known that images can be modeled by various planes result from the projective parallax under non-ideal imaging condition. The dominant-plane homography has important advantages of warping an image globally and avoiding some local distortions. The proposed method primarily addresses large parallax problem through two steps: (1) selecting matching point pairs located on the dominant plane, by clustering matching correspondences and then measuring the cost of each cluster; and (2) in order to obtain a plausible seam, edge maps of overlapped area incorporation arithmetic is adopted to modify the standard seam-cutting method. Furthermore, our approach is demonstrated to achieve reliable performance of handling parallax through a mass of experimental comparisons with state-of-the-art methods.

The 'last mile' of data handling: Fermilab's IFDH tools

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lyon, Adam L.; Mengel, Marc W.

2014-01-01

IFDH (Intensity Frontier Data Handling), is a suite of tools for data movement tasks for Fermilab experiments and is an important part of the FIFE[2] (Fabric for Intensity Frontier [1] Experiments) initiative described at this conference. IFDH encompasses moving input data from caches or storage elements to compute nodes (the 'last mile' of data movement) and moving output data potentially to those caches as part of the journey back to the user. IFDH also involves throttling and locking to ensure that large numbers of jobs do not cause data movement bottlenecks. IFDH is realized as an easy to use layermore » that users call in their job scripts (e.g. 'ifdh cp'), hiding the low level data movement tools. One advantage of this layer is that the underlying low level tools can be selected or changed without the need for the user to alter their scripts. Logging and performance monitoring can also be added easily. This system will be presented in detail as well as its impact on the ease of data handling at Fermilab experiments.« less

Improving Predictions and Management of Hydrological Extremes through Climate Services

NASA Astrophysics Data System (ADS)

van den Hurk, Bart; Wijngaard, Janet; Pappenberger, Florian; Bouwer, Laurens; Weerts, Albrecht; Buontempo, Carlo; Doescher, Ralf; Manez, Maria; Ramos, Maria-Helena; Hananel, Cedric; Ercin, Ertug; Hunink, Johannes; Klein, Bastian; Pouget, Laurent; Ward, Philip

2016-04-01

The EU Roadmap on Climate Services can be seen as a result of convergence between the society's call for "actionable research", and the climate research community providing tailored data, information and knowledge. However, although weather and climate have clearly distinct definitions, a strong link between weather and climate services exists that is not explored extensively. Stakeholders being interviewed in the context of the Roadmap consider climate as a far distant long term feature that is difficult to consider in present-day decision taking, which is dominated by daily experience with handling extreme events. It is argued that this experience is a rich source of inspiration to increase society's resilience to an unknown future. A newly started European research project, IMPREX, is built on the notion that "experience in managing current day weather extremes is the best learning school to anticipate consequences of future climate". This paper illustrates possible ways to increase the link between information and services addressing weather and climate time scales by discussing the underlying concepts of IMPREX and its expected outcome.

16 CFR 1207.10 - Handling, storage, and marking.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Handling, storage, and marking. 1207.10... REGULATIONS SAFETY STANDARD FOR SWIMMING POOL SLIDES § 1207.10 Handling, storage, and marking. (a) Marking... identification of the manufacturer. (b) Shipping, handling, and storage. The slide shall be designed, constructed...

16 CFR 1207.10 - Handling, storage, and marking.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Handling, storage, and marking. 1207.10... REGULATIONS SAFETY STANDARD FOR SWIMMING POOL SLIDES § 1207.10 Handling, storage, and marking. (a) Marking... identification of the manufacturer. (b) Shipping, handling, and storage. The slide shall be designed, constructed...

16 CFR 1207.10 - Handling, storage, and marking.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Handling, storage, and marking. 1207.10... REGULATIONS SAFETY STANDARD FOR SWIMMING POOL SLIDES § 1207.10 Handling, storage, and marking. (a) Marking... identification of the manufacturer. (b) Shipping, handling, and storage. The slide shall be designed, constructed...

16 CFR 1207.10 - Handling, storage, and marking.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Handling, storage, and marking. 1207.10... REGULATIONS SAFETY STANDARD FOR SWIMMING POOL SLIDES § 1207.10 Handling, storage, and marking. (a) Marking... identification of the manufacturer. (b) Shipping, handling, and storage. The slide shall be designed, constructed...

Predictability and possible earlier awareness of extreme precipitation across Europe

NASA Astrophysics Data System (ADS)

Lavers, David; Pappenberger, Florian; Richardson, David; Zsoter, Ervin

2017-04-01

Extreme hydrological events can cause large socioeconomic damages in Europe. In winter, a large proportion of these flood episodes are associated with atmospheric rivers, a region of intense water vapour transport within the warm sector of extratropical cyclones. When preparing for such extreme events, forecasts of precipitation from numerical weather prediction models or river discharge forecasts from hydrological models are generally used. Given the strong link between water vapour transport (integrated vapour transport IVT) and heavy precipitation, it is possible that IVT could be used to warn of extreme events. Furthermore, as IVT is located in extratropical cyclones, it is hypothesized to be a more predictable variable due to its link with synoptic-scale atmospheric dynamics. In this research, we firstly provide an overview of the predictability of IVT and precipitation forecasts, and secondly introduce and evaluate the ECMWF Extreme Forecast Index (EFI) for IVT. The EFI is a tool that has been developed to evaluate how ensemble forecasts differ from the model climate, thus revealing the extremeness of the forecast. The ability of the IVT EFI to capture extreme precipitation across Europe during winter 2013/14, 2014/15, and 2015/16 is presented. The results show that the IVT EFI is more capable than the precipitation EFI of identifying extreme precipitation in forecast week 2 during forecasts initialized in a positive North Atlantic Oscillation (NAO) phase. However, the precipitation EFI is superior during the negative NAO phase and at shorter lead times. An IVT EFI example is shown for storm Desmond in December 2015 highlighting its potential to identify upcoming hydrometeorological extremes.

Procedures to handle inventory cluster plots that straddle two or more conditions

Treesearch

Jerold T. Hahn; Colin D. MacLean; Stanford L. Arner; William A. Bechtold

1995-01-01

We review the relative merits and field procedures for four basic plot designs to handle forest inventory plots that straddle two or more conditions, given that subplots will not be moved. A cluster design is recommended that combines fixed-area subplots and variable-radius plot (VRP) sampling. Each subplot in a cluster consists of a large fixed-area subplot for...

30 CFR 77.606 - Energized trailing cables; handling.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Energized trailing cables; handling. 77.606... COAL MINES Trailing Cables § 77.606 Energized trailing cables; handling. Energized medium- and high-voltage trailing cables shall be handled only by persons wearing protective rubber gloves (see § 77.606-1...

Materials Handling. Module SH-01. Safety and Health.

ERIC Educational Resources Information Center

Center for Occupational Research and Development, Inc., Waco, TX.

This student module on materials handling is one of 50 modules concerned with job safety and health. It presents the procedures for safe materials handling. Discussed are manual handling methods (lifting and carrying by hand) and mechanical lifting (lifting by powered trucks, cranes or conveyors). Following the introduction, 15 objectives (each…

Incorporating Handling Qualities Analysis into Rotorcraft Conceptual Design

NASA Technical Reports Server (NTRS)

Lawrence, Ben

2014-01-01

This paper describes the initial development of a framework to incorporate handling qualities analyses into a rotorcraft conceptual design process. In particular, the paper describes how rotorcraft conceptual design level data can be used to generate flight dynamics models for handling qualities analyses. Also, methods are described that couple a basic stability augmentation system to the rotorcraft flight dynamics model to extend analysis to beyond that of the bare airframe. A methodology for calculating the handling qualities characteristics of the flight dynamics models and for comparing the results to ADS-33E criteria is described. Preliminary results from the application of the handling qualities analysis for variations in key rotorcraft design parameters of main rotor radius, blade chord, hub stiffness and flap moment of inertia are shown. Varying relationships, with counteracting trends for different handling qualities criteria and different flight speeds are exhibited, with the action of the control system playing a complex part in the outcomes. Overall, the paper demonstrates how a broad array of technical issues across flight dynamics stability and control, simulation and modeling, control law design and handling qualities testing and evaluation had to be confronted to implement even a moderately comprehensive handling qualities analysis of relatively low fidelity models. A key outstanding issue is to how to 'close the loop' with an overall design process, and options for the exploration of how to feedback handling qualities results to a conceptual design process are proposed for future work.

Comparison of upper extremity glenohumeral joint forces in children with cerebral palsy using anterior and posterior walkers - biomed 2009.

PubMed

Strifling, Kelly M B; Konop, Katherine A; Wang, Mei; Harris, Gerald F

2009-01-01

Walkers are prescribed with the notion that one type of walker will be better for a child than another. One underlying justification for this practice is the theory that one walker may produce less stress on the upper extremities as the patient uses the walker. Nevertheless, upper extremity joint loading is not typically analyzed during walker assisted gait in children with spastic diplegic cerebral palsy. It has been difficult to evaluate the theory of walker prescription based on upper extremity stresses because loading on the upper extremities however has not been quantified until recently. In this study, weight bearing on the glenohumeral joints was analyzed in five children with spastic diplegic cerebral palsy using both anterior and posterior walkers fitted with 6-axis handle transducers. Though walkers' effects on the upper extremities proved to be similar between walker types, the differences between the walkers may have some clinical significance in the long run. In general, posterior walker use created larger glenohumeral joint forces. Though these differences are not statistically significant, over time and with repetitive loading they may be clinically significant.

A Generalized Framework for Non-Stationary Extreme Value Analysis

NASA Astrophysics Data System (ADS)

Ragno, E.; Cheng, L.; Sadegh, M.; AghaKouchak, A.

2017-12-01

Empirical trends in climate variables including precipitation, temperature, snow-water equivalent at regional to continental scales are evidence of changes in climate over time. The evolving climate conditions and human activity-related factors such as urbanization and population growth can exert further changes in weather and climate extremes. As a result, the scientific community faces an increasing demand for updated appraisal of the time-varying climate extremes. The purpose of this study is to offer a robust and flexible statistical tool for non-stationary extreme value analysis which can better characterize the severity and likelihood of extreme climatic variables. This is critical to ensure a more resilient environment in a changing climate. Following the positive feedback on the first version of Non-Stationary Extreme Value Analysis (NEVA) Toolbox by Cheng at al. 2014, we present an improved version, i.e. NEVA2.0. The upgraded version herein builds upon a newly-developed hybrid evolution Markov Chain Monte Carlo (MCMC) approach for numerical parameters estimation and uncertainty assessment. This addition leads to a more robust uncertainty estimates of return levels, return periods, and risks of climatic extremes under both stationary and non-stationary assumptions. Moreover, NEVA2.0 is flexible in incorporating any user-specified covariate other than the default time-covariate (e.g., CO2 emissions, large scale climatic oscillation patterns). The new feature will allow users to examine non-stationarity of extremes induced by physical conditions that underlie the extreme events (e.g. antecedent soil moisture deficit, large-scale climatic teleconnections, urbanization). In addition, the new version offers an option to generate stationary and/or non-stationary rainfall Intensity - Duration - Frequency (IDF) curves that are widely used for risk assessment and infrastructure design. Finally, a Graphical User Interface (GUI) of the package is provided, making NEVA

Extreme events and natural hazards: The complexity perspective

NASA Astrophysics Data System (ADS)

Schultz, Colin

2012-10-01

Advanced societies have become quite proficient at defending against moderate-size earthquakes, hurricanes, floods, or other natural assaults. What still pose a significant threat, however, are the unknowns, the extremes, the natural phenomena encompassed by the upper tail of the probability distribution. Alongside the large or powerful events, truly extreme natural disasters are those that tie different systems together: an earthquake that causes a tsunami, which leads to flooding, which takes down a nuclear reactor. In the geophysical monograph Extreme Events and Natural Hazards: The Complexity Perspective, editors A. Surjalal Sharma, Armin Bunde, Vijay P. Dimro, and Daniel N. Baker present a lens through which such multidisciplinary phenomena can be understood. In this interview, Eos talks to Sharma about complexity science, predicting extreme events and natural hazards, and the push for "big data."

Cophasing techniques for extremely large telescopes

NASA Astrophysics Data System (ADS)

Devaney, Nicholas; Schumacher, Achim

2004-07-01

The current designs of the majority of ELTs envisage that at least the primary mirror will be segmented. Phasing of the segments is therefore a major concern, and a lot of work is underway to determine the most suitable techniques. The techniques which have been developed are either wave optics generalizations of classical geometric optics tests (e.g. Shack-Hartmann and curvature sensing) or direct interferometric measurements. We present a review of the main techniques proposed for phasing and outline their relative merits. We consider problems which are specific to ELTs, e.g. vignetting of large parts of the primary mirror by the secondary mirror spiders, and the need to disentangle phase errors arising in different segmented mirrors. We present improvements in the Shack-Hartmann and curvature sensing techniques which allow greater precision and range. Finally, we describe a piston plate which simulates segment phasing errors and show the results of laboratory experiments carried out to verify the precision of the Shack-Hartmann technique.

Advanced Curation Protocols for Mars Returned Sample Handling

NASA Astrophysics Data System (ADS)

Bell, M.; Mickelson, E.; Lindstrom, D.; Allton, J.

Introduction: Johnson Space Center has over 30 years experience handling precious samples which include Lunar rocks and Antarctic meteorites. However, we recognize that future curation of samples from such missions as Genesis, Stardust, and Mars S mple Return, will require a high degree of biosafety combined witha extremely low levels of inorganic, organic, and biological contamination. To satisfy these requirements, research in the JSC Advanced Curation Lab is currently focused toward two major areas: preliminary examination techniques and cleaning and verification techniques . Preliminary Examination Techniques : In order to minimize the number of paths for contamination we are exploring the synergy between human &robotic sample handling in a controlled environment to help determine the limits of clean curation. Within the Advanced Curation Laboratory is a prototype, next-generation glovebox, which contains a robotic micromanipulator. The remotely operated manipulator has six degrees-of- freedom and can be programmed to perform repetitive sample handling tasks. Protocols are being tested and developed to perform curation tasks such as rock splitting, weighing, imaging, and storing. Techniques for sample transfer enabling more detailed remote examination without compromising the integrity of sample science are also being developed . The glovebox is equipped with a rapid transfer port through which samples can be passed without exposure. The transfer is accomplished by using a unique seal and engagement system which allows passage between containers while maintaining a first seal to the outside environment and a second seal to prevent the outside of the container cover and port door from becoming contaminated by the material being transferred. Cleaning and Verification Techniques: As part of the contamination control effort, innovative cleaning techniques are being identified and evaluated in conjunction with sensitive cleanliness verification methods. Towards this

How to Handle Impasses in Bargaining.

ERIC Educational Resources Information Center

Durrant, Robert E.

Guidelines in an outline format are presented to school board members and administrators on how to handle impasses in bargaining. The following two rules are given: there sometimes may be strikes, but there always will be settlements; and on the way to settlements, there always will be impasses. Suggestions for handling impasses are listed under…

Neonatal handling and reproductive function in female rats.

PubMed

Gomes, C M; Raineki, C; Ramos de Paula, P; Severino, G S; Helena, C V V; Anselmo-Franci, J A; Franci, C R; Sanvitto, G L; Lucion, A B

2005-02-01

Neonatal handling induces anovulatory estrous cycles and decreases sexual receptivity in female rats. The synchronous secretion of hormones from the gonads (estradiol (E2) and progesterone (P)), pituitary (luteinizing (LH) and follicle-stimulating (FSH) hormones) and hypothalamus (LH-releasing hormone (LHRH)) are essential for the reproductive functions in female rats. The present study aimed to describe the plasma levels of E2 and P throughout the estrous cycle and LH, FSH and prolactin (PRL) in the afternoon of the proestrus, and the LHRH content in the medial preoptic area (MPOA), median eminence (ME) and medial septal area (MSA) in the proestrus, in the neonatal handled rats. Wistar pup rats were handled for 1 min during the first 10 days after delivery (neonatal handled group) or left undisturbed (nonhandled group). When they reached adulthood, blood samples were collected through a jugular cannula and the MPOA, ME and MSA were microdissected. Plasma levels of the hormones and the content of LHRH were determined by RIA. The number of oocytes counted in the morning of the estrus day in the handled rats was significantly lower than in the nonhandled ones. Neonatal handling reduces E2 levels only on the proestrus day while P levels decreased in metestrus and estrus. Handled females also showed reduced plasma levels of LH, FSH and PRL in the afternoon of the proestrus. The LHRH content in the MPOA was significantly higher than in the nonhandled group. The reduced secretion of E2, LH, FSH and LHRH on the proestrus day may explain the anovulatory estrous cycle in neonatal handled rats. The reduced secretion of PRL in the proestrus may be related to the decreased sexual receptiveness in handled females. In conclusion, early-life environmental stimulation can induce long-lasting effects on the hypothalamus-pituitary-gonad axis.

Differences among nursing homes in outcomes of a safe resident handling program.

PubMed

Kurowski, Alicia; Gore, Rebecca; Buchholz, Bryan; Punnett, Laura

2012-01-01

A large nursing home corporation implemented a safe resident handling program (SRHP) in 2004-2007. We evaluated its efficacy over a 2-year period by examining differences among 5 centers in program outcomes and potential predictors of those differences. We observed nursing assistants (NAs), recording activities and body postures at 60-second intervals on personal digital assistants at baseline and at 3-month, 12-month, and 24-month follow-ups. The two outcomes computed were change in equipment use during resident handling and change in a physical workload index that estimated spinal loading due to body postures and handled loads. Potential explanatory factors were extracted from post-observation interviews, investigator surveys of the workforce, from administrative data, and employee satisfaction surveys. The facility with the most positive outcome measures was associated with many positive changes in explanatory factors and the facility with the fewest positive outcome measures experienced negative changes in the same factors. These findings suggest greater SRHP benefits where there was lower NA turnover and agency staffing; less time pressure; and better teamwork, staff communication, and supervisory support. © 2012 American Society for Healthcare Risk Management of the American Hospital Association.

Changes in extremes due to half a degree warming in observations and models

NASA Astrophysics Data System (ADS)

Fischer, E. M.; Schleussner, C. F.; Pfleiderer, P.

2017-12-01

Assessing the climate impacts of half-a-degree warming increments is high on the post-Paris science agenda. Discriminating those effects is particularly challenging for climate extremes such as heavy precipitation and heat extremes for which model uncertainties are generally large, and for which internal variability is so important that it can easily offset or strongly amplify the forced local changes induced by half a degree warming. Despite these challenges we provide evidence for large-scale changes in the intensity and frequency of climate extremes due to half a degree warming. We first assess the difference in extreme climate indicators in observational data for the 1960s and 1970s versus the recent past, two periods differ by half a degree. We identify distinct differences for the global and continental-scale occurrence of heat and heavy precipitation extremes. We show that those observed changes in heavy precipitation and heat extremes broadly agree with simulated historical differences and are informative for the projected differences between 1.5 and 2°C warming despite different radiative forcings. We therefore argue that evidence from the observational record can inform the debate about discernible climate impacts in the light of model uncertainty by providing a conservative estimate of the implications of 0.5°C warming. A limitation of using the observational record arises from potential non-linearities in the response of climate extremes to a certain level of warming. We test for potential non-linearities in the response of heat and heavy precipitation extremes in a large ensemble of transient climate simulations. We further quantify differences between a time-window approach in a coupled model large ensemble vs. time-slice experiments using prescribed SST experiments performed in the context of the HAPPI-MIP project. Thereby we provide different lines of evidence that half a degree warming leads to substantial changes in the expected occurrence of

Quinone-induced protein handling changes: Implications for major protein handling systems in quinone-mediated toxicity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xiong, Rui; Siegel, David; Ross, David, E-mail: david.ross@ucdenver.edu

2014-10-15

Para-quinones such as 1,4-Benzoquinone (BQ) and menadione (MD) and ortho-quinones including the oxidation products of catecholamines, are derived from xenobiotics as well as endogenous molecules. The effects of quinones on major protein handling systems in cells; the 20/26S proteasome, the ER stress response, autophagy, chaperone proteins and aggresome formation, have not been investigated in a systematic manner. Both BQ and aminochrome (AC) inhibited proteasomal activity and activated the ER stress response and autophagy in rat dopaminergic N27 cells. AC also induced aggresome formation while MD had little effect on any protein handling systems in N27 cells. The effect of NQO1more » on quinone induced protein handling changes and toxicity was examined using N27 cells stably transfected with NQO1 to generate an isogenic NQO1-overexpressing line. NQO1 protected against BQ–induced apoptosis but led to a potentiation of AC- and MD-induced apoptosis. Modulation of quinone-induced apoptosis in N27 and NQO1-overexpressing cells correlated only with changes in the ER stress response and not with changes in other protein handling systems. These data suggested that NQO1 modulated the ER stress response to potentiate toxicity of AC and MD, but protected against BQ toxicity. We further demonstrated that NQO1 mediated reduction to unstable hydroquinones and subsequent redox cycling was important for the activation of the ER stress response and toxicity for both AC and MD. In summary, our data demonstrate that quinone-specific changes in protein handling are evident in N27 cells and the induction of the ER stress response is associated with quinone-mediated toxicity. - Highlights: • Unstable hydroquinones contributed to quinone-induced ER stress and toxicity.« less

Effect of a worktable position on head and shoulder posture and shoulder muscles in manual material handling.

PubMed

Kim, Min-Hee; Yoo, Won-Gyu

2015-06-05

According to a recent research, manual working with high levels of static contraction, repetitive loads, or extreme working postures involving the neck and shoulder muscles causes an increased risk of neck and shoulder musculoskeletal disorders. We investigated the effects of the forwardly worktable position on head and shoulder angles and shoulder muscle activity in manual material handling tasks. The forward head and shoulder angles and the activity of upper trapezius, levator scapulae, and middle deltoid muscle activities of 15 workers were measured during performing of manual material handling in two tasks that required different forward head and shoulder angles. The second manual material task required a significantly increased forward head and shoulder angle. The upper trapezius and levator scapulae muscle activity in second manual material task was increased significantly compared with first manual material task. The middle deltoid muscle activity in second manual material task was not significantly different compared with first manual material task. Based on this result, the forward head and shoulder angles while performing manual work need to be considered in selection of the forward distance of a worktable form the body. The high level contractions of the neck and shoulder muscles correlated with neck and shoulder pain. Therefore, the forward distance of a worktable can be an important factor in preventing neck and shoulder pain in manual material handling workers.

The influence of handling qualities on safety and survivability

NASA Technical Reports Server (NTRS)

Anderson, S. B.

1977-01-01

The relationship of handling qualities to safety and survivability of military aircraft is examined which includes the following: (1) a brief discussion of the philosophy used in the military specifications for treatment of degraded handling qualities, (2) an examination of several example handling qualities problem areas which influence safety and survivability; and (3) a movie illustrating the potential dangers of inadequate handling qualities features.

Handling Kids in Crisis with Care

ERIC Educational Resources Information Center

Bushinski, Cari

2018-01-01

The Handle with Care program helps schools help students who experience trauma. While at the scene of an event like a domestic violence call, drug raid, or car accident, law enforcement personnel determine the names and school of any children present. They notify that child's school to "handle ___ with care" the next day, and the school…

Ground-Handling Forces on a 1/40-scale Model of the U. S. Airship "Akron."

NASA Technical Reports Server (NTRS)

Silverstein, Abe; Gulick, B G

1937-01-01

This report presents the results of full-scale wind tunnel tests conducted to determine the ground-handling forces on a 1/40-scale model of the U. S. Airship "Akron." Ground-handling conditions were simulated by establishing a velocity gradient above a special ground board in the tunnel comparable with that encountered over a landing field. The tests were conducted at Reynolds numbers ranging from 5,000,000 to 19,000,000 at each of six angles of yaw between 0 degree and 180 degrees and at four heights of the model above the ground board. The ground-handling forces vary greatly with the angle of yaw and reach large values at appreciable angles of yaw. Small changes in height, pitch, or roll did not critically affect the forces on the model. In the range of Reynolds numbers tested, no significant variation of the forces with the scale was disclosed.

Lux in obscuro II: photon orbits of extremal AdS black holes revisited

NASA Astrophysics Data System (ADS)

Tang, Zi-Yu; Ong, Yen Chin; Wang, Bin

2017-12-01

A large class of spherically symmetric static extremal black hole spacetimes possesses a stable null photon sphere on their horizons. For the extremal Kerr-Newman family, the photon sphere only really coincides with the horizon in the sense clarified by Doran. The condition under which a photon orbit is stable on an asymptotically flat extremal Kerr-Newman black hole horizon has recently been clarified; it is found that a sufficiently large angular momentum destabilizes the photon orbit, whereas an electrical charge tends to stabilize it. We investigated the effect of a negative cosmological constant on this observation, and found the same behavior in the case of extremal asymptotically Kerr-Newman-AdS black holes in (3+1) -dimensions. In (2+1) -dimensions, in the presence of an electrical charge, the angular momentum never becomes large enough to destabilize the photon orbit. We comment on the instabilities of black hole spacetimes with a stable photon orbit.

Comparison of the Effects of Walking with and without Nordic Pole on Upper Extremity and Lower Extremity Muscle Activation.

PubMed

Shim, Je-Myung; Kwon, Hae-Yeon; Kim, Ha-Roo; Kim, Bo-In; Jung, Ju-Hyeon

2013-12-01

[Purpose] The aim of this study was to assess the effect of Nordic pole walking on the electromyographic activities of upper extremity and lower extremity muscles. [Subjects and Methods] The subjects were randomly divided into two groups as follows: without Nordic pole walking group (n=13) and with Nordic pole walking group (n=13). The EMG data were collected by measurement while the subjects walking on a treadmill for 30 minutes by measuring from one heel strike to the next. [Results] Both the average values and maximum values of the muscle activity of the upper extremity increased in both the group that used Nordic poles and the group that did not use Nordic poles, and the values showed statistically significant differences. There was an increase in the average value for muscle activity of the latissimus dorsi, but the difference was not statistically significant, although there was a statistically significant increase in its maximum value. The average and maximum values for muscle activity of the lower extremity did not show large differences in either group, and the values did not show any statistically significant differences. [Conclusion] The use of Nordic poles by increased muscle activity of the upper extremity compared with regular walking but did not affect the lower extremity.

Comparison of the Effects of Walking with and without Nordic Pole on Upper Extremity and Lower Extremity Muscle Activation

PubMed Central

Shim, Je-myung; Kwon, Hae-yeon; Kim, Ha-roo; Kim, Bo-in; Jung, Ju-hyeon

2014-01-01

[Purpose] The aim of this study was to assess the effect of Nordic pole walking on the electromyographic activities of upper extremity and lower extremity muscles. [Subjects and Methods] The subjects were randomly divided into two groups as follows: without Nordic pole walking group (n=13) and with Nordic pole walking group (n=13). The EMG data were collected by measurement while the subjects walking on a treadmill for 30 minutes by measuring from one heel strike to the next. [Results] Both the average values and maximum values of the muscle activity of the upper extremity increased in both the group that used Nordic poles and the group that did not use Nordic poles, and the values showed statistically significant differences. There was an increase in the average value for muscle activity of the latissimus dorsi, but the difference was not statistically significant, although there was a statistically significant increase in its maximum value. The average and maximum values for muscle activity of the lower extremity did not show large differences in either group, and the values did not show any statistically significant differences. [Conclusion] The use of Nordic poles by increased muscle activity of the upper extremity compared with regular walking but did not affect the lower extremity. PMID:24409018

Dielectric Elastomer Actuators for Soft Wave-Handling Systems.

PubMed

Wang, Tao; Zhang, Jinhua; Hong, Jun; Wang, Michael Yu

2017-03-01

This article presents a soft handling system inspired by the principle of the natural wave (named Wave-Handling system) aiming to offer a soft solution to delicately transport and sort fragile items such as fruits, vegetables, biological tissues in food, and biological industries. The system consists of an array of hydrostatically coupled dielectric elastomer actuators (HCDEAs). Due to the electrostriction property of dielectric elastomers, the handling system can be controlled by electric voltage rather than the cumbersome pneumatic system. To study the working performance of the Wave-Handling system and how the performance can be improved, the basic properties of HCDEA are investigated through experiments. We find that the HCDEA exhibits some delay and hysteretic characteristics when activated by periodic voltage and the characteristics are influenced by the frequency and external force also. All this will affect the performance of the Wave-Handling system. However, the electric control, simple structure, light weight, and low cost of the soft handling system show great potential to move from laboratory to practical application. As a proof of design concept, a simply made prototype of the handling system is controlled to generate a parallel moving wave to manipulate a ball. Based on the experimental results, the improvements and future work are discussed and we believe this work will provide inspiration for soft robotic engineering.

The NOAO NEWFIRM Data Handling System

NASA Astrophysics Data System (ADS)

Zárate, N.; Fitzpatrick, M.

2008-08-01

The NOAO Extremely Wide-Field IR Mosaic (NEWFIRM) is a new 1-2.4 micron IR camera that is now being commissioned for the 4m Mayall telescope at Kitt Peak. The focal plane consists of a 2x2 mosaic of 2048x2048 arrays offerring a field-of-view of 27.6' on a side. The use of dual MONSOON array controllers permits very fast readout, a scripting interface allows for highly efficient observing modes. We describe the Data Handling System (DHS) for the NEWFIRM camera which is designed to meet the performance requirements of the instrument as well as the observing environment in which in operates. It is responsible for receiving the data stream from the detector and instrument software, rectifying the image geometry, presenting a real-time display of the image to the user, final assembly of a science-grade image with complete headers, as well as triggering automated pipeline and archival functions. The DHS uses an event-based messaging system to control multiple processes on a distributed network of machines. The asynchronous nature of this processing means the DHS operates independently from the camera readout and the design of the system is inherently scalable to larger focal planes that use a greater number of array controllers. Current status and future plans for the DHS are also discussed.

New Insights into Handling Missing Values in Environmental Epidemiological Studies

PubMed Central

Roda, Célina; Nicolis, Ioannis; Momas, Isabelle; Guihenneuc, Chantal

2014-01-01

Missing data are unavoidable in environmental epidemiologic surveys. The aim of this study was to compare methods for handling large amounts of missing values: omission of missing values, single and multiple imputations (through linear regression or partial least squares regression), and a fully Bayesian approach. These methods were applied to the PARIS birth cohort, where indoor domestic pollutant measurements were performed in a random sample of babies' dwellings. A simulation study was conducted to assess performances of different approaches with a high proportion of missing values (from 50% to 95%). Different simulation scenarios were carried out, controlling the true value of the association (odds ratio of 1.0, 1.2, and 1.4), and varying the health outcome prevalence. When a large amount of data is missing, omitting these missing data reduced statistical power and inflated standard errors, which affected the significance of the association. Single imputation underestimated the variability, and considerably increased risk of type I error. All approaches were conservative, except the Bayesian joint model. In the case of a common health outcome, the fully Bayesian approach is the most efficient approach (low root mean square error, reasonable type I error, and high statistical power). Nevertheless for a less prevalent event, the type I error is increased and the statistical power is reduced. The estimated posterior distribution of the OR is useful to refine the conclusion. Among the methods handling missing values, no approach is absolutely the best but when usual approaches (e.g. single imputation) are not sufficient, joint modelling approach of missing process and health association is more efficient when large amounts of data are missing. PMID:25226278

Large Prominence Eruption [video

NASA Image and Video Library

2014-10-07

The STEREO (Behind) spacecraft captured this large prominence and corona mass ejection as they erupted into space (Sept. 26, 2014). By combining images from three instruments, scientists can see the eruption itself (in extreme UV light) as well as follow its progression over the period of about 13 hours with its two coronagraphs. Credit: NASA/Goddard/STEREO The STEREO (Behind) spacecraft captured this large prominence and corona mass ejection as they erupted into space (Sept. 26, 2014). By combining images from three instruments, scientists can see the eruption itself (in extreme UV light) as well as follow its progression over the period of about 13 hours with its two coronagraphs.

Overseas Absentee Ballot Handling in DOD

DTIC Science & Technology

2001-06-22

Performed . We reviewed pertinent laws, policies, and guidance dated from May 1980 through January 2000 related to the absentee ballot process and the...OVERSEAS ABSENTEE BALLOT HANDLING IN DOD Report No. D-2001-145 June 22, 2001 Office of the Inspector...34) Title and Subtitle Overseas Absentee Ballot Handling in DOD Contract or Grant Number Program Element Number Authors Project Number Task Number

An efficient predictor-corrector-based dynamic mesh method for multi-block structured grid with extremely large deformation and its applications

NASA Astrophysics Data System (ADS)

Guo, Tongqing; Chen, Hao; Lu, Zhiliang

2018-05-01

Aiming at extremely large deformation, a novel predictor-corrector-based dynamic mesh method for multi-block structured grid is proposed. In this work, the dynamic mesh generation is completed in three steps. At first, some typical dynamic positions are selected and high-quality multi-block grids with the same topology are generated at those positions. Then, Lagrange interpolation method is adopted to predict the dynamic mesh at any dynamic position. Finally, a rapid elastic deforming technique is used to correct the small deviation between the interpolated geometric configuration and the actual instantaneous one. Compared with the traditional methods, the results demonstrate that the present method shows stronger deformation ability and higher dynamic mesh quality.

The Effect of Tool Handle Shape on Hand Muscle Load and Pinch Force in a Simulated Dental Scaling Task

PubMed Central

Dong, Hui; Loomer, Peter; Barr, Alan; LaRoche, Charles; Young, Ed; Rempel, David

2007-01-01

Work-related upper extremity musculoskeletal disorders, including carpal tunnel syndrome, are prevalent among dentists and dental hygienists. An important risk factor for developing these disorders is forceful pinching which occurs during periodontal work such as dental scaling. Ergonomically designed dental scaling instruments may help reduce the prevalence of carpal tunnel syndrome among dental practitioners. In this study, 8 custom-designed dental scaling instruments with different handle shapes were used by 24 dentists and dental hygienists to perform a simulated tooth scaling task. The muscle activity of two extensors and two flexors in the forearm was recorded with electromyography while thumb pinch force was measured by pressure sensors. The results demonstrated that the instrument handle with a tapered, round shape and a 10 mm diameter required the least muscle load and pinch force when performing simulated periodontal work. The results from this study can guide dentists and dental hygienists in selection of dental scaling instruments. PMID:17156742

ECMWF Extreme Forecast Index for water vapor transport: A forecast tool for atmospheric rivers and extreme precipitation

NASA Astrophysics Data System (ADS)

Lavers, David A.; Pappenberger, Florian; Richardson, David S.; Zsoter, Ervin

2016-11-01

In winter, heavy precipitation and floods along the west coasts of midlatitude continents are largely caused by intense water vapor transport (integrated vapor transport (IVT)) within the atmospheric river of extratropical cyclones. This study builds on previous findings that showed that forecasts of IVT have higher predictability than precipitation, by applying and evaluating the European Centre for Medium-Range Weather Forecasts Extreme Forecast Index (EFI) for IVT in ensemble forecasts during three winters across Europe. We show that the IVT EFI is more able (than the precipitation EFI) to capture extreme precipitation in forecast week 2 during forecasts initialized in a positive North Atlantic Oscillation (NAO) phase; conversely, the precipitation EFI is better during the negative NAO phase and at shorter leads. An IVT EFI example for storm Desmond in December 2015 highlights its potential to identify upcoming hydrometeorological extremes, which may prove useful to the user and forecasting communities.

Some issues related to the novel spectral acceleration method for the fast computation of radiation/scattering from one-dimensional extremely large scale quasi-planar structures

NASA Astrophysics Data System (ADS)

Torrungrueng, Danai; Johnson, Joel T.; Chou, Hsi-Tseng

2002-03-01

The novel spectral acceleration (NSA) algorithm has been shown to produce an $[\\mathcal{O}]$(Ntot) efficient iterative method of moments for the computation of radiation/scattering from both one-dimensional (1-D) and two-dimensional large-scale quasi-planar structures, where Ntot is the total number of unknowns to be solved. This method accelerates the matrix-vector multiplication in an iterative method of moments solution and divides contributions between points into ``strong'' (exact matrix elements) and ``weak'' (NSA algorithm) regions. The NSA method is based on a spectral representation of the electromagnetic Green's function and appropriate contour deformation, resulting in a fast multipole-like formulation in which contributions from large numbers of points to a single point are evaluated simultaneously. In the standard NSA algorithm the NSA parameters are derived on the basis of the assumption that the outermost possible saddle point, φs,max, along the real axis in the complex angular domain is small. For given height variations of quasi-planar structures, this assumption can be satisfied by adjusting the size of the strong region Ls. However, for quasi-planar structures with large height variations, the adjusted size of the strong region is typically large, resulting in significant increases in computational time for the computation of the strong-region contribution and degrading overall efficiency of the NSA algorithm. In addition, for the case of extremely large scale structures, studies based on the physical optics approximation and a flat surface assumption show that the given NSA parameters in the standard NSA algorithm may yield inaccurate results. In this paper, analytical formulas associated with the NSA parameters for an arbitrary value of φs,max are presented, resulting in more flexibility in selecting Ls to compromise between the computation of the contributions of the strong and weak regions. In addition, a ``multilevel'' algorithm

Impact of climate change on European weather extremes

NASA Astrophysics Data System (ADS)

Duchez, Aurelie; Forryan, Alex; Hirschi, Joel; Sinha, Bablu; New, Adrian; Freychet, Nicolas; Scaife, Adam; Graham, Tim

2015-04-01

An emerging science consensus is that global climate change will result in more extreme weather events with concomitant increasing financial losses. Key questions that arise are: Can an upward trend in natural extreme events be recognised and predicted at the European scale? What are the key drivers within the climate system that are changing and making extreme weather events more frequent, more intense, or both? Using state-of-the-art coupled climate simulations from the UK Met Office (HadGEM3-GC2, historical and future scenario runs) as well as reanalysis data, we highlight the potential of the currently most advanced forecasting systems to progress understanding of the causative drivers of European weather extremes, and assess future frequency and intensity of extreme weather under various climate change scenarios. We characterize European extremes in these simulations using a subset of the 27 core indices for temperature and precipitation from The Expert Team on Climate Change Detection and Indices (Tank et al., 2009). We focus on temperature and precipitation extremes (e.g. extremes in daily and monthly precipitation and temperatures) and relate them to the atmospheric modes of variability over Europe in order to establish the large-scale atmospheric circulation patterns that are conducive to the occurrence of extreme precipitation and temperature events. Klein Tank, Albert M.G., and Francis W. Zwiers. Guidelines on Analysis of Extremes in a Changing Climate in Support of Informed Decisions for Adaptation. WMO-TD No. 1500. Climate Data and Monitoring. World Meteorological Organization, 2009.

Tunable Resistance or Magnetoresistance Cusp and Extremely Large Magnetoresistance in Defect-Engineered HfTe5 -δ Single Crystals

NASA Astrophysics Data System (ADS)

Lv, Yang-Yang; Li, Xiao; Cao, Lin; Lin, Dajun; Yao, Shu-Hua; Chen, Si-Si; Dong, Song-Tao; Zhou, Jian; Chen, Y. B.; Chen, Yan-Feng

2018-05-01

The electrical transport behaviors of novel materials under the external magnetic field B , especially the large or tunable magnetoresistance (MR) effect, are of broad importance in both fundamental science and applications. Here three kinds of HfTe5 crystals with varied Te-deficiency concentrations are synthesized under different growth conditions, and they demonstrate distinct electrical and magnetotransport properties. The temperatures of the resistivity cusp or MR cusp of the as-grown HfTe5 -δ (δ =0.02 , 0.08, 0.13) crystals are tuned from 25 to 90 K. The maximum MR of these three HfTe5 -δ crystals, under 2 K and 9 T B , are 1.52 ×103% , 2.63 ×104% , and 6.91 ×103% for sample SI (HfTe4.98 ), SII (HfTe4.92 ), and SIII (HfTe4.87 ), respectively. The fitting of Hall data by the two-carrier model suggests that the extremely large MR effect of sample HfTe4.92 measured at 2 K is attributed to the cooperative action of the high mobility and the coexistence of the electron and hole carriers. Our work provides a viable route to tune superior MR properties in similar compounds through defect engineering, which may be promising to develop magnetic memory sensor devices.

The Impacts of Atmospheric Rivers on California's Extreme Precipitation

NASA Astrophysics Data System (ADS)

Asgari Lamjiri, M.; Dettinger, M. D.; Ralph, M.

2017-12-01

Atmospheric rivers (ARs) are long, narrow corridors of enhanced water vapor transport that are typically associated with extratropical cyclones. ARs can be beneficial and replenish water resources, be hazardous and cause damaging floods, or have a combination of hazardous and beneficial impacts. Thus, understanding hydrologic impacts of ARs can help to improve water reservoir management and enhance flood risk mitigation, especially in California where there is extremely large year-to-year variability in annual precipitation accumulations. At the continental scale, gridded hourly precipitation observations are used in this study to identify unique characteristics of precipitation events impacting the US west coast compared to other regions in the US; precipitation events are defined here as continuous periods of precipitation with at least 5 mm of accumulated precipitation. It is shown that on average, the US west coast receives the largest precipitation totals across the US; these extreme precipitation events are largely associated with the most persistent ARs. Within California, hourly precipitation observations from 200 sites are being analyzed to better understand distinct categories of ARs that dictate extreme precipitation in different regions of California. It is found that, on average, the north coast, northern Sierra, and the Transverse Ranges experience the largest precipitation events; north coast and northern Sierra precipitation events tend to be longer, whereas the Transverse Ranges generally experience higher maximum and event-averaged intensities. ARs contribute significantly to extreme precipitation events in all regions of California, particularly the north coast, northern Sierra, and the Transverse Ranges. ARs associated with extreme precipitation events across California are significantly more persistent and have higher integrated vapor transport intensities than those associated with non-extreme events. Composites of characteristics of ARs which

Power-Tool Adapter For T-Handle Screws

NASA Technical Reports Server (NTRS)

Deloach, Stephen R.

1992-01-01

Proposed adapter enables use of pneumatic drill, electric drill, electric screwdriver, or similar power tool to tighten or loosen T-handled screws. Notched tube with perpendicular rod welded to it inserted in chuck of tool. Notched end of tube slipped over screw handle.

Direct handling of equality constraints in multilevel optimization

NASA Technical Reports Server (NTRS)

Renaud, John E.; Gabriele, Gary A.

1990-01-01

In recent years there have been several hierarchic multilevel optimization algorithms proposed and implemented in design studies. Equality constraints are often imposed between levels in these multilevel optimizations to maintain system and subsystem variable continuity. Equality constraints of this nature will be referred to as coupling equality constraints. In many implementation studies these coupling equality constraints have been handled indirectly. This indirect handling has been accomplished using the coupling equality constraints' explicit functional relations to eliminate design variables (generally at the subsystem level), with the resulting optimization taking place in a reduced design space. In one multilevel optimization study where the coupling equality constraints were handled directly, the researchers encountered numerical difficulties which prevented their multilevel optimization from reaching the same minimum found in conventional single level solutions. The researchers did not explain the exact nature of the numerical difficulties other than to associate them with the direct handling of the coupling equality constraints. The coupling equality constraints are handled directly, by employing the Generalized Reduced Gradient (GRG) method as the optimizer within a multilevel linear decomposition scheme based on the Sobieski hierarchic algorithm. Two engineering design examples are solved using this approach. The results show that the direct handling of coupling equality constraints in a multilevel optimization does not introduce any problems when the GRG method is employed as the internal optimizer. The optimums achieved are comparable to those achieved in single level solutions and in multilevel studies where the equality constraints have been handled indirectly.

Disaster Risks Reduction for Extreme Natural Hazards

NASA Astrophysics Data System (ADS)

Plag, H.; Jules-Plag, S.

2013-12-01

Mega disasters associated with extreme natural hazards have the potential to escalate the global sustainability crisis and put us close to the boundaries of the safe operating space for humanity. Floods and droughts are major threats that potentially could reach planetary extent, particularly through secondary economic and social impacts. Earthquakes and tsunamis frequently cause disasters that eventually could exceed the immediate coping capacity of the global economy, particularly since we have built mega cities in hazardous areas that are now ready to be harvested by natural hazards. Unfortunately, the more we learn to cope with the relatively frequent hazards (50 to 100 years events), the less we are worried about the low-probability, high-impact events (a few hundred and more years events). As a consequence, threats from the 500 years flood, drought, volcano eruption are not appropriately accounted for in disaster risk reduction (DRR) discussions. Extreme geohazards have occurred regularly throughout the past, but mostly did not cause major disasters because exposure of human assets to hazards was much lower in the past. The most extreme events that occurred during the last 2,000 years would today cause unparalleled damage on a global scale and could worsen the sustainability crisis. Simulation of these extreme hazards under present conditions can help to assess the disaster risk. Recent extreme earthquakes have illustrated the destruction they can inflict, both directly and indirectly through tsunamis. Large volcano eruptions have the potential to impact climate, anthropogenic infrastructure and resource supplies on global scale. During the last 2,000 years several large volcano eruptions occurred, which under today's conditions are associated with extreme disaster risk. The comparison of earthquakes and volcano eruptions indicates that large volcano eruptions are the low-probability geohazards with potentially the highest impact on our civilization

Redefining NHS complaint handling--the real challenge.

PubMed

Seelos, L; Adamson, C

1994-01-01

More and more organizations find that a constructive and open dialogue with their customers can be an effective strategy for building long-term customer relations. In this context, it has been recognized that effective complaint-contact handling can make a significant contribution to organizations' attempts to maximize customer satisfaction and loyalty. Within the NHS, an intellectual awareness exists that effective complaint/contact handling can contribute to making services more efficient and cost-effective by developing customer-oriented improvement initiatives. Recent efforts have focused on redefining NHS complaint-handling procedures to make them more user-friendly and effective for both NHS employees and customers. Discusses the challenges associated with opening up the NHS to customer feedback. Highlights potential weaknesses in the current approach and argues that the real challenge is for NHS managers to facilitate a culture change that moves the NHS away from a long-established defensive complaint handling practice.

Present-day irrigation mitigates heat extremes

DOE PAGES

Thiery, Wim; Davin, Edouard L.; Lawrence, David M.; ...

2017-02-16

Irrigation is an essential practice for sustaining global food production and many regional economies. Emerging scientific evidence indicates that irrigation substantially affects mean climate conditions in different regions of the world. Yet how this practice influences climate extremes is currently unknown. Here we use ensemble simulations with the Community Earth System Model to assess the impacts of irrigation on climate extremes. An evaluation of the model performance reveals that irrigation has a small yet overall beneficial effect on the representation of present-day near-surface climate. While the influence of irrigation on annual mean temperatures is limited, we find a large impactmore » on temperature extremes, with a particularly strong cooling during the hottest day of the year (-0.78 K averaged over irrigated land). The strong influence on extremes stems from the timing of irrigation and its influence on land-atmosphere coupling strength. Together these effects result in asymmetric temperature responses, with a more pronounced cooling during hot and/or dry periods. The influence of irrigation is even more pronounced when considering subgrid-scale model output, suggesting that local effects of land management are far more important than previously thought. In conclusion, our results underline that irrigation has substantially reduced our exposure to hot temperature extremes in the past and highlight the need to account for irrigation in future climate projections.« less

Present-day irrigation mitigates heat extremes

NASA Astrophysics Data System (ADS)

Thiery, Wim; Davin, Edouard L.; Lawrence, David M.; Hirsch, Annette L.; Hauser, Mathias; Seneviratne, Sonia I.

2017-02-01

Irrigation is an essential practice for sustaining global food production and many regional economies. Emerging scientific evidence indicates that irrigation substantially affects mean climate conditions in different regions of the world. Yet how this practice influences climate extremes is currently unknown. Here we use ensemble simulations with the Community Earth System Model to assess the impacts of irrigation on climate extremes. An evaluation of the model performance reveals that irrigation has a small yet overall beneficial effect on the representation of present-day near-surface climate. While the influence of irrigation on annual mean temperatures is limited, we find a large impact on temperature extremes, with a particularly strong cooling during the hottest day of the year (-0.78 K averaged over irrigated land). The strong influence on extremes stems from the timing of irrigation and its influence on land-atmosphere coupling strength. Together these effects result in asymmetric temperature responses, with a more pronounced cooling during hot and/or dry periods. The influence of irrigation is even more pronounced when considering subgrid-scale model output, suggesting that local effects of land management are far more important than previously thought. Our results underline that irrigation has substantially reduced our exposure to hot temperature extremes in the past and highlight the need to account for irrigation in future climate projections.

49 CFR 176.57 - Supervision of handling and stowage.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 2 2011-10-01 2011-10-01 false Supervision of handling and stowage. 176.57 Section 176.57 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS... VESSEL General Handling and Stowage § 176.57 Supervision of handling and stowage. (a) Hazardous materials...

49 CFR 176.57 - Supervision of handling and stowage.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 2 2014-10-01 2014-10-01 false Supervision of handling and stowage. 176.57 Section 176.57 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS... VESSEL General Handling and Stowage § 176.57 Supervision of handling and stowage. (a) Hazardous materials...

49 CFR 176.57 - Supervision of handling and stowage.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 2 2012-10-01 2012-10-01 false Supervision of handling and stowage. 176.57 Section 176.57 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS... VESSEL General Handling and Stowage § 176.57 Supervision of handling and stowage. (a) Hazardous materials...

49 CFR 176.57 - Supervision of handling and stowage.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Supervision of handling and stowage. 176.57 Section 176.57 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS... VESSEL General Handling and Stowage § 176.57 Supervision of handling and stowage. (a) Hazardous materials...

49 CFR 176.57 - Supervision of handling and stowage.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 2 2013-10-01 2013-10-01 false Supervision of handling and stowage. 176.57 Section 176.57 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS... VESSEL General Handling and Stowage § 176.57 Supervision of handling and stowage. (a) Hazardous materials...

A powerful and efficient set test for genetic markers that handles confounders

PubMed Central

Listgarten, Jennifer; Lippert, Christoph; Kang, Eun Yong; Xiang, Jing; Kadie, Carl M.; Heckerman, David

2013-01-01

Motivation: Approaches for testing sets of variants, such as a set of rare or common variants within a gene or pathway, for association with complex traits are important. In particular, set tests allow for aggregation of weak signal within a set, can capture interplay among variants and reduce the burden of multiple hypothesis testing. Until now, these approaches did not address confounding by family relatedness and population structure, a problem that is becoming more important as larger datasets are used to increase power. Results: We introduce a new approach for set tests that handles confounders. Our model is based on the linear mixed model and uses two random effects—one to capture the set association signal and one to capture confounders. We also introduce a computational speedup for two random-effects models that makes this approach feasible even for extremely large cohorts. Using this model with both the likelihood ratio test and score test, we find that the former yields more power while controlling type I error. Application of our approach to richly structured Genetic Analysis Workshop 14 data demonstrates that our method successfully corrects for population structure and family relatedness, whereas application of our method to a 15 000 individual Crohn’s disease case–control cohort demonstrates that it additionally recovers genes not recoverable by univariate analysis. Availability: A Python-based library implementing our approach is available at http://mscompbio.codeplex.com. Contact: jennl@microsoft.com or lippert@microsoft.com or heckerma@microsoft.com Supplementary information: Supplementary data are available at Bioinformatics online. PMID:23599503

Extreme geomagnetically induced currents

NASA Astrophysics Data System (ADS)

Kataoka, Ryuho; Ngwira, Chigomezyo

2016-12-01

We propose an emergency alert framework for geomagnetically induced currents (GICs), based on the empirically extreme values and theoretical upper limits of the solar wind parameters and of d B/d t, the time derivative of magnetic field variations at ground. We expect this framework to be useful for preparing against extreme events. Our analysis is based on a review of various papers, including those presented during Extreme Space Weather Workshops held in Japan in 2011, 2012, 2013, and 2014. Large-amplitude d B/d t values are the major cause of hazards associated with three different types of GICs: (1) slow d B/d t with ring current evolution (RC-type), (2) fast d B/d t associated with auroral electrojet activity (AE-type), and (3) transient d B/d t of sudden commencements (SC-type). We set "caution," "warning," and "emergency" alert levels during the main phase of superstorms with the peak Dst index of less than -300 nT (once per 10 years), -600 nT (once per 60 years), or -900 nT (once per 100 years), respectively. The extreme d B/d t values of the AE-type GICs are 2000, 4000, and 6000 nT/min at caution, warning, and emergency levels, respectively. For the SC-type GICs, a "transient alert" is also proposed for d B/d t values of 40 nT/s at low latitudes and 110 nT/s at high latitudes, especially when the solar energetic particle flux is unusually high.

TECA: A Parallel Toolkit for Extreme Climate Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Prabhat, Mr; Ruebel, Oliver; Byna, Surendra

2012-03-12

We present TECA, a parallel toolkit for detecting extreme events in large climate datasets. Modern climate datasets expose parallelism across a number of dimensions: spatial locations, timesteps and ensemble members. We design TECA to exploit these modes of parallelism and demonstrate a prototype implementation for detecting and tracking three classes of extreme events: tropical cyclones, extra-tropical cyclones and atmospheric rivers. We process a modern TB-sized CAM5 simulation dataset with TECA, and demonstrate good runtime performance for the three case studies.

A Test-Length Correction to the Estimation of Extreme Proficiency Levels

ERIC Educational Resources Information Center

Magis, David; Beland, Sebastien; Raiche, Gilles

2011-01-01

In this study, the estimation of extremely large or extremely small proficiency levels, given the item parameters of a logistic item response model, is investigated. On one hand, the estimation of proficiency levels by maximum likelihood (ML), despite being asymptotically unbiased, may yield infinite estimates. On the other hand, with an…

Attribution of extreme rainfall from Hurricane Harvey, August 2017

NASA Astrophysics Data System (ADS)

van Oldenborgh, Geert Jan; van der Wiel, Karin; Sebastian, Antonia; Singh, Roop; Arrighi, Julie; Otto, Friederike; Haustein, Karsten; Li, Sihan; Vecchi, Gabriel; Cullen, Heidi

2017-12-01

During August 25-30, 2017, Hurricane Harvey stalled over Texas and caused extreme precipitation, particularly over Houston and the surrounding area on August 26-28. This resulted in extensive flooding with over 80 fatalities and large economic costs. It was an extremely rare event: the return period of the highest observed three-day precipitation amount, 1043.4 mm 3dy-1 at Baytown, is more than 9000 years (97.5% one-sided confidence interval) and return periods exceeded 1000 yr (750 mm 3dy-1) over a large area in the current climate. Observations since 1880 over the region show a clear positive trend in the intensity of extreme precipitation of between 12% and 22%, roughly two times the increase of the moisture holding capacity of the atmosphere expected for 1 °C warming according to the Clausius-Clapeyron (CC) relation. This would indicate that the moisture flux was increased by both the moisture content and stronger winds or updrafts driven by the heat of condensation of the moisture. We also analysed extreme rainfall in the Houston area in three ensembles of 25 km resolution models. The first also shows 2 × CC scaling, the second 1 × CC scaling and the third did not have a realistic representation of extreme rainfall on the Gulf Coast. Extrapolating these results to the 2017 event, we conclude that global warming made the precipitation about 15% (8%-19%) more intense, or equivalently made such an event three (1.5-5) times more likely. This analysis makes clear that extreme rainfall events along the Gulf Coast are on the rise. And while fortifying Houston to fully withstand the impact of an event as extreme as Hurricane Harvey may not be economically feasible, it is critical that information regarding the increasing risk of extreme rainfall events in general should be part of the discussion about future improvements to Houston’s flood protection system.

7 CFR 959.126 - Handling of culls.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Handling of culls. 959.126 Section 959.126 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements...) Handled for canning or freezing. (b) As a safeguard against culls entering fresh market channels each...

Data handling for the modular observatory

NASA Technical Reports Server (NTRS)

Taber, J. E.

1975-01-01

The current paper summarizes work undertaken at TRW for the EOS satellite and related missions, and it presents conclusions that lead to a flexible and low-cost overall system implementation. It shows how the usual communication and data handling functions must be altered to meet the modularization ground rules, and it demonstrates the modularization that is possible in the handling of wideband payload data both on board and on the ground.

Cooper-Harper Experience Report for Spacecraft Handling Qualities Applications

NASA Technical Reports Server (NTRS)

Bailey, Randall E.; Jackson, E. Bruce; Bilimoria, Karl D.; Mueller, Eric R.; Frost, Chad R.; Alderete, Thomas S.

2009-01-01

A synopsis of experience from the fixed-wing and rotary-wing aircraft communities in handling qualities development and the use of the Cooper-Harper pilot rating scale is presented as background for spacecraft handling qualities research, development, test, and evaluation (RDT&E). In addition, handling qualities experiences and lessons-learned from previous United States (US) spacecraft developments are reviewed. This report is intended to provide a central location for references, best practices, and lessons-learned to guide current and future spacecraft handling qualities RDT&E.

Cellular Manufacturing System with Dynamic Lot Size Material Handling

NASA Astrophysics Data System (ADS)

Khannan, M. S. A.; Maruf, A.; Wangsaputra, R.; Sutrisno, S.; Wibawa, T.

2016-02-01

Material Handling take as important role in Cellular Manufacturing System (CMS) design. In several study at CMS design material handling was assumed per pieces or with constant lot size. In real industrial practice, lot size may change during rolling period to cope with demand changes. This study develops CMS Model with Dynamic Lot Size Material Handling. Integer Linear Programming is used to solve the problem. Objective function of this model is minimizing total expected cost consisting machinery depreciation cost, operating costs, inter-cell material handling cost, intra-cell material handling cost, machine relocation costs, setup costs, and production planning cost. This model determines optimum cell formation and optimum lot size. Numerical examples are elaborated in the paper to ilustrate the characterictic of the model.

Extreme Conditions Modeling Workshop Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coe, Ryan Geoffrey; Neary, Vincent Sinclair; Lawon, Michael J.

2014-07-01

Sandia National Laboratories (SNL) and the National Renewable Energy Laboratory (NREL) hosted the Wave Energy Converter (WEC) Extreme Conditions Modeling (ECM) Workshop in Albuquerque, New Mexico on May 13–14, 2014. The objective of the workshop was to review the current state of knowledge on how to numerically and experimentally model WECs in extreme conditions (e.g. large ocean storms) and to suggest how national laboratory resources could be used to improve ECM methods for the benefit of the wave energy industry. More than 30 U.S. and European WEC experts from industry, academia, and national research institutes attended the workshop, which consistedmore » of presentations from W EC developers, invited keynote presentations from subject matter experts, breakout sessions, and a final plenary session .« less

Extreme Magnitude Earthquakes and their Economical Consequences

NASA Astrophysics Data System (ADS)

Chavez, M.; Cabrera, E.; Ashworth, M.; Perea, N.; Emerson, D.; Salazar, A.; Moulinec, C.

2011-12-01

The frequency of occurrence of extreme magnitude earthquakes varies from tens to thousands of years, depending on the considered seismotectonic region of the world. However, the human and economic losses when their hypocenters are located in the neighborhood of heavily populated and/or industrialized regions, can be very large, as recently observed for the 1985 Mw 8.01 Michoacan, Mexico and the 2011 Mw 9 Tohoku, Japan, earthquakes. Herewith, a methodology is proposed in order to estimate the probability of exceedance of: the intensities of extreme magnitude earthquakes, PEI and of their direct economical consequences PEDEC. The PEI are obtained by using supercomputing facilities to generate samples of the 3D propagation of extreme earthquake plausible scenarios, and enlarge those samples by Monte Carlo simulation. The PEDEC are computed by using appropriate vulnerability functions combined with the scenario intensity samples, and Monte Carlo simulation. An example of the application of the methodology due to the potential occurrence of extreme Mw 8.5 subduction earthquakes on Mexico City is presented.

Anders Breivik: Extreme Beliefs Mistaken for Psychosis.

PubMed

Rahman, Tahir; Resnick, Phillip J; Harry, Bruce

2016-03-01

The case of Anders Breivik, who committed mass murder in Norway in 2011, stirred controversy among forensic mental health experts. His bizarrely composed compendium and references to himself as the "Knights Templar" raised concerns that he had a psychotic mental illness. Beliefs such as Mr. Breivik's that precede odd, unusual, or extremely violent behavior present a unique challenge to the forensic evaluator, who sometimes struggles to understand those beliefs. Psychotic disorder frequently is invoked to characterize odd, unusual, or extreme beliefs, with a classification that has evolved over time. However, the important concept of overvalued idea, largely ignored in American psychiatry, may better characterize these beliefs in some cases. We discuss the definitions of delusion and overvalued ideas in the context of Anders Breivik's rigidly held extreme beliefs. We also review the British definition of overvalued idea and discuss McHugh's construct, to introduce the term "extreme overvalued belief" as an aid in sharpening the forensic evaluator's conceptualization of these and similar beliefs. © 2016 American Academy of Psychiatry and the Law.

Cardiovascular consequences of extreme prematurity: the EPICure study.

PubMed

McEniery, Carmel M; Bolton, Charlotte E; Fawke, Joseph; Hennessy, Enid; Stocks, Janet; Wilkinson, Ian B; Cockcroft, John R; Marlow, Neil

2011-07-01

The long-term consequences of extreme prematurity are becoming increasingly important, given recent improvements in neonatal intensive care. The aim of the current study was to examine the cardiovascular consequences of extreme prematurity in 11-year-olds born at or before 25 completed weeks of gestation. Age and sex-matched classmates were recruited as controls. Information concerning perinatal and maternal history was collected, and current anthropometric characteristics were measured in 219 children born extremely preterm and 153 classmates. A subset of the extremely preterm children (n = 68) and classmates (n = 90) then underwent detailed haemodynamic investigations, including measurement of supine blood pressure (BP), aortic pulse wave velocity (aPWV, a measure of aortic stiffness) and augmentation index (AIx, a measure of arterial pressure wave reflections). Seated brachial systolic and diastolic BP were not different between extremely preterm children and classmates (P = 0.3 for both), although there was a small, significant elevation in supine mean and diastolic BP in the extremely preterm children (P < 0.05 for both). Arterial pressure wave reflections were significantly elevated in the extremely preterm children (P < 0.001) and this persisted after adjusting for confounding variables. However, aortic stiffness was not different between the groups (P = 0.1). These data suggest that extreme prematurity is associated with altered arterial haemodynamics in children, not evident from the examination of brachial BP alone. Moreover, the smaller, preresistance and resistance vessels rather than large elastic arteries appear to be most affected. Children born extremely preterm may be at increased future cardiovascular risk.

Functional studies in 79-year-olds. II. Upper extremity function.

PubMed

Lundgren-Lindquist, B; Sperling, L

1983-01-01

As part of the Gerontological and Geriatric Population Study of 79-year-old people in Göteborg, a representative subsample comprising 112 women and 93 men took part in a study of upper extremity function. Thirty-eight per cent of the women and 37% of the men had disorders in the upper extremities. The investigation included tests of co-ordination, static strength in the key-grip and the transversal volar grip, power capacity in opening jars and a bottle, basal movements in the upper extremities in personal hygiene and dressing activities, function in the kitchen e.g. reaching shelves, manual tasks including tests of pronation and supination of the forearm. In the key-grip as well as in the transversal volar grip men showed a generally larger decrease in strength with age than women compared to 70-year-olds in a previous population study. Significant correlations were found between strength in the key-grip and the performance time in the test of co-ordination. Women produced about 66% of the muscular force of the men when opening jars. Significant correlations were found between strength in the transversal volar grip and the maximal torque for opening the jars. Female and male subjects who were not capable of handling the electric plug in the manual ability test had significantly weaker strength in the key-grip. The importance of designing products and adapting the environment so as to correspond to the functional capacity of the elderly, is emphasized.

20 CFR 658.421 - Handling of JS-related complaints.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Handling of JS-related complaints. 658.421... ADMINISTRATIVE PROVISIONS GOVERNING THE JOB SERVICE SYSTEM Job Service Complaint System Federal Js Complaint System § 658.421 Handling of JS-related complaints. (a) No JS-related complaint shall be handled at the...

16 CFR § 1207.10 - Handling, storage, and marking.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Handling, storage, and marking. § 1207.10... REGULATIONS SAFETY STANDARD FOR SWIMMING POOL SLIDES § 1207.10 Handling, storage, and marking. (a) Marking... identification of the manufacturer. (b) Shipping, handling, and storage. The slide shall be designed, constructed...

Extreme fluctuations in stochastic network coordination with time delays

NASA Astrophysics Data System (ADS)

Hunt, D.; Molnár, F.; Szymanski, B. K.; Korniss, G.

2015-12-01

We study the effects of uniform time delays on the extreme fluctuations in stochastic synchronization and coordination problems with linear couplings in complex networks. We obtain the average size of the fluctuations at the nodes from the behavior of the underlying modes of the network. We then obtain the scaling behavior of the extreme fluctuations with system size, as well as the distribution of the extremes on complex networks, and compare them to those on regular one-dimensional lattices. For large complex networks, when the delay is not too close to the critical one, fluctuations at the nodes effectively decouple, and the limit distributions converge to the Fisher-Tippett-Gumbel density. In contrast, fluctuations in low-dimensional spatial graphs are strongly correlated, and the limit distribution of the extremes is the Airy density. Finally, we also explore the effects of nonlinear couplings on the stability and on the extremes of the synchronization landscapes.

Handling qualities effects of display latency

NASA Technical Reports Server (NTRS)

King, David W.

1993-01-01

Display latency is the time delay between aircraft response and the corresponding response of the cockpit displays. Currently, there is no explicit specification for allowable display lags to ensure acceptable aircraft handling qualities in instrument flight conditions. This paper examines the handling qualities effects of display latency between 70 and 400 milliseconds for precision instrument flight tasks of the V-22 Tiltrotor aircraft. Display delay effects on the pilot control loop are analytically predicted through a second order pilot crossover model of the V-22 lateral axis, and handling qualities trends are evaluated through a series of fixed-base piloted simulation tests. The results show that the effects of display latency for flight path tracking tasks are driven by the stability characteristics of the attitude control loop. The data indicate that the loss of control damping due to latency can be simply predicted from knowledge of the aircraft's stability margins, control system lags, and required control bandwidths. Based on the relationship between attitude control damping and handling qualities ratings, latency design guidelines are presented. In addition, this paper presents a design philosophy, supported by simulation data, for using flight director display augmentation to suppress the effects of display latency for delays up to 300 milliseconds.

Alternative Methods for Handling Attrition

PubMed Central

Foster, E. Michael; Fang, Grace Y.

2009-01-01

Using data from the evaluation of the Fast Track intervention, this article illustrates three methods for handling attrition. Multiple imputation and ignorable maximum likelihood estimation produce estimates that are similar to those based on listwise-deleted data. A panel selection model that allows for selective dropout reveals that highly aggressive boys accumulate in the treatment group over time and produces a larger estimate of treatment effect. In contrast, this model produces a smaller treatment effect for girls. The article's conclusion discusses the strengths and weaknesses of the alternative approaches and outlines ways in which researchers might improve their handling of attrition. PMID:15358906

Ceramics for Molten Materials Containment, Transfer and Handling on the Lunar Surface

NASA Technical Reports Server (NTRS)

Standish, Evan; Stefanescu, Doru M.; Curreri, Peter A.

2009-01-01

As part of a project on Molten Materials Transfer and Handling on the Lunar Surface, molten materials containment samples of various ceramics were tested to determine their performance in contact with a melt of lunar regolith simulant. The test temperature was 1600 C with contact times ranging from 0 to 12 hours. Regolith simulant was pressed into cylinders with the approximate dimensions of 1.25 dia x 1.25cm height and then melted on ceramic substrates. The regolith-ceramic interface was examined after processing to determine the melt/ceramic interaction. It was found that the molten regolith wetted all oxide ceramics tested extremely well which resulted in chemical reaction between the materials in each case. Alumina substrates were identified which withstood contact at the operating temperature of a molten regolith electrolysis cell (1600 C) for eight hours with little interaction or deformation. This represents an improvement over alumina grades currently in use and will provide a lifetime adequate for electrolysis experiments lasting 24 hours or more. Two types of non-oxide ceramics were also tested. It was found that they interacted to a limited degree with the melt resulting in little corrosion. These ceramics, Sic and BN, were not wetted as well as the oxides by the melt, and so remain possible materials for molten regolith handling. Tests wing longer holding periods and larger volumes of regolith are necessary to determine the ultimate performance of the tested ceramics.

Extreme fluctuations of active Brownian motion

NASA Astrophysics Data System (ADS)

Pietzonka, Patrick; Kleinbeck, Kevin; Seifert, Udo

2016-05-01

In active Brownian motion, an internal propulsion mechanism interacts with translational and rotational thermal noise and other internal fluctuations to produce directed motion. We derive the distribution of its extreme fluctuations and identify its universal properties using large deviation theory. The limits of slow and fast internal dynamics give rise to a kink-like and parabolic behavior of the corresponding rate functions, respectively. For dipolar Janus particles in two- and three-dimensions interacting with a field, we predict a novel symmetry akin to, but different from, the one related to entropy production. Measurements of these extreme fluctuations could thus be used to infer properties of the underlying, often hidden, network of states.

MHSS: a material handling system simulator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pomernacki, L.; Hollstien, R.B.

1976-04-07

A Material Handling System Simulator (MHSS) program is described that provides specialized functional blocks for modeling and simulation of nuclear material handling systems. Models of nuclear fuel fabrication plants may be built using functional blocks that simulate material receiving, storage, transport, inventory, processing, and shipping operations as well as the control and reporting tasks of operators or on-line computers. Blocks are also provided that allow the user to observe and gather statistical information on the dynamic behavior of simulated plants over single or replicated runs. Although it is currently being developed for the nuclear materials handling application, MHSS can bemore » adapted to other industries in which material accountability is important. In this paper, emphasis is on the simulation methodology of the MHSS program with application to the nuclear material safeguards problem. (auth)« less

Updates to FuncLab, a Matlab based GUI for handling receiver functions

NASA Astrophysics Data System (ADS)

Porritt, Robert W.; Miller, Meghan S.

2018-02-01

Receiver functions are a versatile tool commonly used in seismic imaging. Depending on how they are processed, they can be used to image discontinuity structure within the crust or mantle or they can be inverted for seismic velocity either directly or jointly with complementary datasets. However, modern studies generally require large datasets which can be challenging to handle; therefore, FuncLab was originally written as an interactive Matlab GUI to assist in handling these large datasets. This software uses a project database to allow interactive trace editing, data visualization, H-κ stacking for crustal thickness and Vp/Vs ratio, and common conversion point stacking while minimizing computational costs. Since its initial release, significant advances have been made in the implementation of web services and changes in the underlying Matlab platform have necessitated a significant revision to the software. Here, we present revisions to the software, including new features such as data downloading via irisFetch.m, receiver function calculations via processRFmatlab, on-the-fly cross-section tools, interface picking, and more. In the descriptions of the tools, we present its application to a test dataset in Michigan, Wisconsin, and neighboring areas following the passage of USArray Transportable Array. The software is made available online at https://robporritt.wordpress.com/software.

MOBBED: a computational data infrastructure for handling large collections of event-rich time series datasets in MATLAB

PubMed Central

Cockfield, Jeremy; Su, Kyungmin; Robbins, Kay A.

2013-01-01

Experiments to monitor human brain activity during active behavior record a variety of modalities (e.g., EEG, eye tracking, motion capture, respiration monitoring) and capture a complex environmental context leading to large, event-rich time series datasets. The considerable variability of responses within and among subjects in more realistic behavioral scenarios requires experiments to assess many more subjects over longer periods of time. This explosion of data requires better computational infrastructure to more systematically explore and process these collections. MOBBED is a lightweight, easy-to-use, extensible toolkit that allows users to incorporate a computational database into their normal MATLAB workflow. Although capable of storing quite general types of annotated data, MOBBED is particularly oriented to multichannel time series such as EEG that have event streams overlaid with sensor data. MOBBED directly supports access to individual events, data frames, and time-stamped feature vectors, allowing users to ask questions such as what types of events or features co-occur under various experimental conditions. A database provides several advantages not available to users who process one dataset at a time from the local file system. In addition to archiving primary data in a central place to save space and avoid inconsistencies, such a database allows users to manage, search, and retrieve events across multiple datasets without reading the entire dataset. The database also provides infrastructure for handling more complex event patterns that include environmental and contextual conditions. The database can also be used as a cache for expensive intermediate results that are reused in such activities as cross-validation of machine learning algorithms. MOBBED is implemented over PostgreSQL, a widely used open source database, and is freely available under the GNU general public license at http://visual.cs.utsa.edu/mobbed. Source and issue reports for MOBBED

MOBBED: a computational data infrastructure for handling large collections of event-rich time series datasets in MATLAB.

PubMed

Cockfield, Jeremy; Su, Kyungmin; Robbins, Kay A

2013-01-01

Experiments to monitor human brain activity during active behavior record a variety of modalities (e.g., EEG, eye tracking, motion capture, respiration monitoring) and capture a complex environmental context leading to large, event-rich time series datasets. The considerable variability of responses within and among subjects in more realistic behavioral scenarios requires experiments to assess many more subjects over longer periods of time. This explosion of data requires better computational infrastructure to more systematically explore and process these collections. MOBBED is a lightweight, easy-to-use, extensible toolkit that allows users to incorporate a computational database into their normal MATLAB workflow. Although capable of storing quite general types of annotated data, MOBBED is particularly oriented to multichannel time series such as EEG that have event streams overlaid with sensor data. MOBBED directly supports access to individual events, data frames, and time-stamped feature vectors, allowing users to ask questions such as what types of events or features co-occur under various experimental conditions. A database provides several advantages not available to users who process one dataset at a time from the local file system. In addition to archiving primary data in a central place to save space and avoid inconsistencies, such a database allows users to manage, search, and retrieve events across multiple datasets without reading the entire dataset. The database also provides infrastructure for handling more complex event patterns that include environmental and contextual conditions. The database can also be used as a cache for expensive intermediate results that are reused in such activities as cross-validation of machine learning algorithms. MOBBED is implemented over PostgreSQL, a widely used open source database, and is freely available under the GNU general public license at http://visual.cs.utsa.edu/mobbed. Source and issue reports for MOBBED

WASTE HANDLING BUILDING VENTILATION SYSTEM DESCRIPTION DOCUMENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

P.A. Kumar

2000-06-21

The Waste Handling Building Ventilation System provides heating, ventilation, and air conditioning (HVAC) for the contaminated, potentially contaminated, and uncontaminated areas of the Monitored Geologic Repository's (MGR) Waste Handling Building (WHB). In the uncontaminated areas, the non-confinement area ventilation system maintains the proper environmental conditions for equipment operation and personnel comfort. In the contaminated and potentially contaminated areas, in addition to maintaining the proper environmental conditions for equipment operation and personnel comfort, the contamination confinement area ventilation system directs potentially contaminated air away from personnel in the WHB and confines the contamination within high-efficiency particulate air (HEPA) filtration units. Themore » contamination confinement areas ventilation system creates airflow paths and pressure zones to minimize the potential for spreading contamination within the building. The contamination confinement ventilation system also protects the environment and the public by limiting airborne releases of radioactive or other hazardous contaminants from the WHB. The Waste Handling Building Ventilation System is designed to perform its safety functions under accident conditions and other Design Basis Events (DBEs) (such as earthquakes, tornadoes, fires, and loss of the primary electric power). Additional system design features (such as compartmentalization with independent subsystems) limit the potential for cross-contamination within the WHB. The system provides status of important system parameters and equipment operation, and provides audible and/or visual indication of off-normal conditions and equipment failures. The Waste Handling Building Ventilation System confines the radioactive and hazardous material within the building such that the release rates comply with regulatory limits. The system design, operations, and maintenance activities incorporate ALARA (as low as is

Addressing as low as reasonably achievable (ALARA) issues: investigation of worker collective external and extremity dose data

DOE PAGES

Cournoyer, Michael Edward; Costigan, Stephen Andrew; Schreiber, Stephen Bruce

2017-03-17

Plutonium emits both neutrons and photons and when it is stored or handled inside a glovebox, both photons and neutrons are significant external radiation hazards. Doses to the extremities are usually dominated by gamma radiation in typical plutonium glovebox operations. Excess external dose can generates stochastic effects consisting of cancer and benign tumors in some organs. Direct doses from radiation sources external to the body are measured by thermoluminescent dosimeters (TLDs) placed on the glovebox worker between the neck and waist. Wrist dosimeters are used to assess externally penetrating radiation including neutrons and provide an estimate of neutron radiation exposuremore » to the extremities. Both TLDs and wrist dosimeters are processed monthly for most glovebox workers. Here, worker collective extremity and external dose data have been analyzed to prevent and mitigate external radiation events through the use of Lean Manufacturing and Six Sigma business practices (LSS). Employing LSS, statistically significant variations (trends) are identified in worker collective extremity and external dose data. Finally, the research results presented in this paper are pivotal to the ultimate focus of this program, which is to minimize external radiation events.« less

Addressing as low as reasonably achievable (ALARA) issues: investigation of worker collective external and extremity dose data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cournoyer, Michael Edward; Costigan, Stephen Andrew; Schreiber, Stephen Bruce

Plutonium emits both neutrons and photons and when it is stored or handled inside a glovebox, both photons and neutrons are significant external radiation hazards. Doses to the extremities are usually dominated by gamma radiation in typical plutonium glovebox operations. Excess external dose can generates stochastic effects consisting of cancer and benign tumors in some organs. Direct doses from radiation sources external to the body are measured by thermoluminescent dosimeters (TLDs) placed on the glovebox worker between the neck and waist. Wrist dosimeters are used to assess externally penetrating radiation including neutrons and provide an estimate of neutron radiation exposuremore » to the extremities. Both TLDs and wrist dosimeters are processed monthly for most glovebox workers. Here, worker collective extremity and external dose data have been analyzed to prevent and mitigate external radiation events through the use of Lean Manufacturing and Six Sigma business practices (LSS). Employing LSS, statistically significant variations (trends) are identified in worker collective extremity and external dose data. Finally, the research results presented in this paper are pivotal to the ultimate focus of this program, which is to minimize external radiation events.« less

21 CFR 58.107 - Test and control article handling.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Test and control article handling. 58.107 Section... GOOD LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Test and Control Articles § 58.107 Test and control article handling. Procedures shall be established for a system for the handling of the test and...

21 CFR 58.107 - Test and control article handling.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Test and control article handling. 58.107 Section... GOOD LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Test and Control Articles § 58.107 Test and control article handling. Procedures shall be established for a system for the handling of the test and...

21 CFR 58.107 - Test and control article handling.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Test and control article handling. 58.107 Section... GOOD LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Test and Control Articles § 58.107 Test and control article handling. Procedures shall be established for a system for the handling of the test and...

21 CFR 58.107 - Test and control article handling.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Test and control article handling. 58.107 Section... GOOD LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Test and Control Articles § 58.107 Test and control article handling. Procedures shall be established for a system for the handling of the test and...

9 CFR 2.131 - Handling of animals.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Handling of animals. 2.131 Section 2.131 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Miscellaneous § 2.131 Handling of animals. (a) All licensees who maintain wild...

9 CFR 2.131 - Handling of animals.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Handling of animals. 2.131 Section 2.131 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Miscellaneous § 2.131 Handling of animals. (a) All licensees who maintain wild...

9 CFR 2.131 - Handling of animals.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Handling of animals. 2.131 Section 2.131 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Miscellaneous § 2.131 Handling of animals. (a) All licensees who maintain wild...

9 CFR 2.131 - Handling of animals.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Handling of animals. 2.131 Section 2.131 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Miscellaneous § 2.131 Handling of animals. (a) All licensees who maintain wild...

Characterization and prediction of extreme events in turbulence

NASA Astrophysics Data System (ADS)

Fonda, Enrico; Iyer, Kartik P.; Sreenivasan, Katepalli R.

2017-11-01

Extreme events in Nature such as tornadoes, large floods and strong earthquakes are rare but can have devastating consequences. The predictability of these events is very limited at present. Extreme events in turbulence are the very large events in small scales that are intermittent in character. We examine events in energy dissipation rate and enstrophy which are several tens to hundreds to thousands of times the mean value. To this end we use our DNS database of homogeneous and isotropic turbulence with Taylor Reynolds numbers spanning a decade, computed with different small scale resolutions and different box sizes, and study the predictability of these events using machine learning. We start with an aggressive data augmentation to virtually increase the number of these rare events by two orders of magnitude and train a deep convolutional neural network to predict their occurrence in an independent data set. The goal of the work is to explore whether extreme events can be predicted with greater assurance than can be done by conventional methods (e.g., D.A. Donzis & K.R. Sreenivasan, J. Fluid Mech. 647, 13-26, 2010).

Intra-seasonal Characteristics of Wintertime Extreme Cold Events over South Korea

NASA Astrophysics Data System (ADS)

Park, Taewon; Jeong, Jeehoon; Choi, Jahyun

2017-04-01

The present study reveals the changes in the characteristics of extreme cold events over South Korea for boreal winter (November to March) in terms of the intra-seasonal variability of frequency, duration, and atmospheric circulation pattern. Influences of large-scale variabilities such as the Siberian High activity, the Arctic Oscillation (AO), and the Madden-Julian Oscillation (MJO) on extreme cold events are also investigated. In the early and the late of the winter during November and March, the upper-tropospheric wave-train for a life-cycle of the extreme cold events tends to pass quickly over East Asia. In addition, compared with the other months, the intensity of the Siberian High is weaker and the occurrences of strong negative AO are less frequent. It lead to events with weak amplitude and short duration. On the other hand, the amplified Siberian High and the strong negative AO occur more frequently in the mid of the winter from December to February. The extreme cold events are mainly characterized by a well-organized anticyclonic blocking around the Ural Mountain and the Subarctic. These large-scale circulation makes the extreme cold events for the midwinter last long with strong amplitude. The MJO phases 2-3 which provide a suitable condition for the amplification of extreme cold events occur frequently for November to January when the frequencies are more than twice those for February and March. While the extreme cold events during March have the least frequency, the weakest amplitude, and the shortest duration due to weak impacts of the abovementioned factors, the strong activities of the factors for January force the extreme cold events to be the most frequent, the strongest, and the longest among the boreal winter. Keywords extreme cold event, wave-train, blocking, Siberian High, AO, MJO

Observation of open-orbit Fermi surface topology in the extremely large magnetoresistance semimetal MoAs2

NASA Astrophysics Data System (ADS)

Lou, R.; Xu, Y. F.; Zhao, L.-X.; Han, Z.-Q.; Guo, P.-J.; Li, M.; Wang, J.-C.; Fu, B.-B.; Liu, Z.-H.; Huang, Y.-B.; Richard, P.; Qian, T.; Liu, K.; Chen, G.-F.; Weng, H. M.; Ding, H.; Wang, S.-C.

2017-12-01

While recent advances in band theory and sample growth have expanded the series of extremely large magnetoresistance (XMR) semimetals in transition-metal dipnictides T m P n2 (T m =Ta , Nb; P n =P , As, Sb), the experimental study on their electronic structure and the origin of XMR is still absent. Here, using angle-resolved photoemission spectroscopy combined with first-principles calculations and magnetotransport measurements, we performed a comprehensive investigation on MoAs2, which is isostructural to the T m P n2 family and also exhibits quadratic XMR. We resolve a clear band structure well agreeing with the predictions. Intriguingly, the unambiguously observed Fermi surfaces (FSs) are dominated by an open-orbit topology extending along both the [100] and [001] directions in the three-dimensional Brillouin zone. We further reveal the trivial topological nature of MoAs2 by bulk parity analysis. Based on these results, we examine the proposed XMR mechanisms in other semimetals, and conclusively ascribe the origin of quadratic XMR in MoAs2 to the carriers motion on the FSs with dominant open-orbit topology, innovating in the understanding of quadratic XMR in semimetals.

Handling Qualities Implications for Crewed Spacecraft Operations

NASA Technical Reports Server (NTRS)

Bailey, Randall E.; Jackson, E. Bruce; Arthur, J. J.

2012-01-01

Abstract Handling qualities embody those qualities or characteristics of an aircraft that govern the ease and precision with which a pilot is able to perform the tasks required in support of an aircraft role. These same qualities are as critical, if not more so, in the operation of spacecraft. A research, development, test, and evaluation process was put into effect to identify, understand, and interpret the engineering and human factors principles which govern the pilot-vehicle dynamic system as they pertain to space exploration missions and tasks. Toward this objective, piloted simulations were conducted at the NASA Langley Research Center and Ames Research Center for earth-orbit proximity operations and docking and lunar landing. These works provide broad guidelines for the design of spacecraft to exhibit excellent handling characteristics. In particular, this work demonstrates how handling qualities include much more than just stability and control characteristics of a spacecraft or aircraft. Handling qualities are affected by all aspects of the pilot-vehicle dynamic system, including the motion, visual and aural cues of the vehicle response as the pilot performs the required operation or task. A holistic approach to spacecraft design, including the use of manual control, automatic control, and pilot intervention/supervision is described. The handling qualities implications of design decisions are demonstrated using these pilot-in-the-loop evaluations of docking operations and lunar landings.

49 CFR 178.915 - General Large Packaging standards.

Code of Federal Regulations, 2010 CFR

2010-10-01

.... Large Packagings intended for solid hazardous materials must be sift-proof and water-resistant. (b) All... materials, the internal pressure of the contents and the stresses of normal handling and transport. A Large... without gross distortion or failure and must be positioned so as to cause no undue stress in any part of...

Changes in extreme events and the potential impacts on human health.

PubMed

Bell, Jesse E; Brown, Claudia Langford; Conlon, Kathryn; Herring, Stephanie; Kunkel, Kenneth E; Lawrimore, Jay; Luber, George; Schreck, Carl; Smith, Adam; Uejio, Christopher

2018-04-01

Extreme weather and climate-related events affect human health by causing death, injury, and illness, as well as having large socioeconomic impacts. Climate change has caused changes in extreme event frequency, intensity, and geographic distribution, and will continue to be a driver for change in the future. Some of these events include heat waves, droughts, wildfires, dust storms, flooding rains, coastal flooding, storm surges, and hurricanes. The pathways connecting extreme events to health outcomes and economic losses can be diverse and complex. The difficulty in predicting these relationships comes from the local societal and environmental factors that affect disease burden. More information is needed about the impacts of climate change on public health and economies to effectively plan for and adapt to climate change. This paper describes some of the ways extreme events are changing and provides examples of the potential impacts on human health and infrastructure. It also identifies key research gaps to be addressed to improve the resilience of public health to extreme events in the future. Extreme weather and climate events affect human health by causing death, injury, and illness, as well as having large socioeconomic impacts. Climate change has caused changes in extreme event frequency, intensity, and geographic distribution, and will continue to be a driver for change in the future. Some of these events include heat waves, droughts, wildfires, flooding rains, coastal flooding, surges, and hurricanes. The pathways connecting extreme events to health outcomes and economic losses can be diverse and complex. The difficulty in predicting these relationships comes from the local societal and environmental factors that affect disease burden.

A two steps solution approach to solving large nonlinear models: application to a problem of conjunctive use.

PubMed

Vieira, J; Cunha, M C

2011-01-01

This article describes a solution method of solving large nonlinear problems in two steps. The two steps solution approach takes advantage of handling smaller and simpler models and having better starting points to improve solution efficiency. The set of nonlinear constraints (named as complicating constraints) which makes the solution of the model rather complex and time consuming is eliminated from step one. The complicating constraints are added only in the second step so that a solution of the complete model is then found. The solution method is applied to a large-scale problem of conjunctive use of surface water and groundwater resources. The results obtained are compared with solutions determined with the direct solve of the complete model in one single step. In all examples the two steps solution approach allowed a significant reduction of the computation time. This potential gain of efficiency of the two steps solution approach can be extremely important for work in progress and it can be particularly useful for cases where the computation time would be a critical factor for having an optimized solution in due time.

Ergonomic design and evaluation of the handle for an endoscopic dissector.

PubMed

Shimomura, Yoshihiro; Minowa, Keita; Kawahira, Hiroshi; Katsuura, Tetsuo

2016-05-01

The purpose of this study was to design an endoscopic dissector handle and objectively assess its usability. The handles were designed with increased contact area between the fingers and thumb and the eye rings, and the eye rings were modified to have a more perpendicular insertion angle to the finger midline. Four different handle models were compared, including a conventional product. Subjects performed dissection, exclusion, grasping, precision manipulation and precision handling tasks. Electromyography and subjective evaluations were measured. Compared to conventional handles, the designated handle reduced the muscle load in the extensor and flexor muscles of the forearm and increased subjective stability. The activity of the first dorsal interosseous muscle was sometimes influenced by the shape of the other parts. The ergonomically designed endoscopic dissector handle used in this study achieved high usability. Medical instrument designs based on ergonomic concepts should be assessed with objective indices. Practitioner Summary: The endoscopic dissector handles were designed with increased contact area and more suitable insertion angle between the fingers and thumb and the eye rings. Compared to conventional handles, the designated handle reduced the muscle load in the extensor and flexor muscles of the forearm and increased subjective stability.

Development of EUV mask handling technology at MIRAI-Selete

NASA Astrophysics Data System (ADS)

Ota, Kazuya; Amemiya, Mitsuaki; Taguchi, Takao; Kamono, Takashi; Kubo, Hiroyoshi; Takikawa, Tadahiko; Usui, Yoichi; Suga, Osamu

2007-03-01

We, MIRAI-Selete, started a new EUV mask program in April, 2006. Development of EUV mask handling technology is one of the key areas of the program. We plan to develop mask handling technology and to evaluate EUV mask carriers using Lasertec M3350, a particle inspection tool with the defect sensitivity less than 50nm PSL, and Mask Protection Engineering Tool (named "MPE Tool"). M3350 is a newly developed tool based on a conventional M1350 for EUV blanks inspection. Since our M3350 has a blank flipping mechanism in it, we can inspect the front and the back surface of the blank automatically. We plan to use the M3350 for evaluating particle adders during mask shipping, storage and handling. MPE Tool is a special tool exclusively developed for demonstration of pellicleless mask handling. It can handle a mask within a protective enclosure, which Canon and Nikon have been jointly proposing1, and also, can be modified to handle other type of carrier as the need arises.

49 CFR 232.111 - Train handling information.

Code of Federal Regulations, 2010 CFR

2010-10-01

... train crew taking charge of a train be informed of: (1) The total weight and length of the train, based... 49 Transportation 4 2010-10-01 2010-10-01 false Train handling information. 232.111 Section 232... TRAINS AND EQUIPMENT; END-OF-TRAIN DEVICES General Requirements § 232.111 Train handling information. (a...

45 CFR 650.19 - Electronic invention handling.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 3 2011-10-01 2011-10-01 false Electronic invention handling. 650.19 Section 650.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION PATENTS § 650.19 Electronic invention handling. (a) Grantees must use the iEdison Invention Information Management System maintained by the National...

45 CFR 650.19 - Electronic invention handling.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 3 2014-10-01 2014-10-01 false Electronic invention handling. 650.19 Section 650.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION PATENTS § 650.19 Electronic invention handling. (a) Grantees must use the iEdison Invention Information Management System maintained by the National...

45 CFR 650.19 - Electronic invention handling.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 3 2013-10-01 2013-10-01 false Electronic invention handling. 650.19 Section 650.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION PATENTS § 650.19 Electronic invention handling. (a) Grantees must use the iEdison Invention Information Management System maintained by the National...

45 CFR 650.19 - Electronic invention handling.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 3 2010-10-01 2010-10-01 false Electronic invention handling. 650.19 Section 650.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION PATENTS § 650.19 Electronic invention handling. (a) Grantees must use the iEdison Invention Information Management System maintained by the National...

Improving Predictions and Management of Hydrological Extremes

NASA Astrophysics Data System (ADS)

Wijngaard, Janet; Liggins, Felicity; Hurk, Bart vd; Lavers, David; Magnusson, Linus; Bouwer, Laurens; Weerts, Albrecht; Kjellström, Erik; Mañez, Maria; Ramos, Maria-Helena; Hananel, Cedric; Ercin, Ertug; Hunink, Johannes; Klein, Bastian; Pouget, Laurent; de Moel, Hans

2017-04-01

The EU Roadmap on Climate Services can be seen as a result of convergence between society's call for "actionable research" and the climate research community's provision of tailored data, information and knowledge. Although weather and climate have distinct definitions, a strong link between weather and climate services does exist but, to date, this link has not been explored extensively. Stakeholders being interviewed in the context of the Roadmap consider changes in our climate as distant, long-term impacts that are difficult to consider in present-day decision making, a process usually dominated by their daily experience with handling adverse weather and extreme events. However, it could be argued that this experience is a rich source of inspiration to increase society's resilience to an unknown future. The European research project, IMPREX, is built on the notion that "experience in managing present day weather extremes can help us anticipate the consequences of future climate variability and change". This presentation illustrates how IMPREX is building the link between the providers and users of information and services addressing both the weather and climate timescales. For different stakeholders in key economic sectors the needs and vulnerabilities in their daily practice are discussed, followed by an analysis of how weather and climate (W&C) services could contribute to the demands that arise from this. Examples of case studies showing the relevance of the tailored W&C information in users' operations will be included.

Storage and handling of aviation fuels at airports

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1988-01-01

This standard covers the basic principles for the design of fuel handling facilities and equipment at airports. It provides a reference for the planning and operation of aviation fuel handling facilities and associated equipment.

Changes in Extreme Events and the Potential Impacts on National Security

NASA Astrophysics Data System (ADS)

Bell, J.

2017-12-01

Extreme weather and climate events affect human health by causing death, injury, and illness, as well as having large socio-economic impacts. Climate change has caused changes in extreme event frequency, intensity and geographic distribution, and will continue to be a driver for changes in the future. Some of the extreme events that have already changed are heat waves, droughts, wildfires, flooding rains, coastal flooding, storm surge, and hurricanes. The pathways connecting extreme events to health outcomes and economic losses can be diverse and complex. The difficulty in predicting these relationships comes from the local intricacies of societal and environmental factors that influences the level of exposure. The goal of this presentation is to discuss the national security implications of changes in extreme weather events and demonstrate how changes in extremes can lead to a host cascading issues. To illustrate this point, this presentation will provide examples of the various pathways that extreme events can increase disease burden and cause economic stress.

Recent Extreme Marine Events at Southern Coast of Black Sea

NASA Astrophysics Data System (ADS)

Ozyurt Tarakcioglu, Gulizar; Cevdet Yalciner, Ahmet; Kirezci, Cagil; Baykal, Cuneyt; Gokhan Guler, Hasan; Erol, Onur; Zaytsev, Andrey; Kurkin, Andrey

2015-04-01

The utilization at the coastal areas of Black Sea basin has increased in the recent years with the projects such as large commercial ports, international transportation hubs, gas and petrol pipelines, touristic and recreational infrastructures both along surrounding shoreline. Although Black Sea is a closed basin, extreme storms and storm surges have also been observed with an increasing frequency in the recent years. Among those events, February 1999, March 2013 and September 2014 storms impacted Southern coast of Black sea have clearly shown that the increasing economic value at the coastal areas caused the increasing cost of damages and loss of property by natural hazards. The storm occurred on February 19-20, 1999 is one of the most destructive storm in the last decades. The 1999 event (1999 Southern Black sea storm) caused destruction at all harbors and coastal protection structures along the Black Sea coast of Turkey. The complete damage of the breakwater of Giresun Harbor and damage on the harbor structures and cargo handling equipment were the major impacts of the 1999 Southern Black sea storm. Similar coastal impact have also been observed during the September 24, 2014 storm at 500m East of Giresun harbor. Although there are considerable number of destructive storms observed at southern coast of Black sea recently, data on these events are limited and vastly scattered. In this study the list of recent extreme marine events at South coast of the Black sea compiled and related data such as wind speed, wave height, period, and type of damages are cataloged. Particular attention is focused on the 1999 and 2014 storm events. The meteorological and morphological characteristics which may be considered as the reasons of the generation and coastal amplification of these storms are discussed. ACKNOWLEDGEMENTS: This study is partly supported by Turkish Russian Joint Research Grant Program by TUBITAK (Turkey) and RFBR (Russia), and TUBITAK 213M534 Research Project.

Orion Entry Handling Qualities Assessments

NASA Technical Reports Server (NTRS)

Bihari, B.; Tiggers, M.; Strahan, A.; Gonzalez, R.; Sullivan, K.; Stephens, J. P.; Hart, J.; Law, H., III; Bilimoria, K.; Bailey, R.

2011-01-01

The Orion Command Module (CM) is a capsule designed to bring crew back from the International Space Station (ISS), the moon and beyond. The atmospheric entry portion of the flight is deigned to be flown in autopilot mode for nominal situations. However, there exists the possibility for the crew to take over manual control in off-nominal situations. In these instances, the spacecraft must meet specific handling qualities criteria. To address these criteria two separate assessments of the Orion CM s entry Handling Qualities (HQ) were conducted at NASA s Johnson Space Center (JSC) using the Cooper-Harper scale (Cooper & Harper, 1969). These assessments were conducted in the summers of 2008 and 2010 using the Advanced NASA Technology Architecture for Exploration Studies (ANTARES) six degree of freedom, high fidelity Guidance, Navigation, and Control (GN&C) simulation. This paper will address the specifics of the handling qualities criteria, the vehicle configuration, the scenarios flown, the simulation background and setup, crew interfaces and displays, piloting techniques, ratings and crew comments, pre- and post-fight briefings, lessons learned and changes made to improve the overall system performance. The data collection tools, methods, data reduction and output reports will also be discussed. The objective of the 2008 entry HQ assessment was to evaluate the handling qualities of the CM during a lunar skip return. A lunar skip entry case was selected because it was considered the most demanding of all bank control scenarios. Even though skip entry is not planned to be flown manually, it was hypothesized that if a pilot could fly the harder skip entry case, then they could also fly a simpler loads managed or ballistic (constant bank rate command) entry scenario. In addition, with the evaluation set-up of multiple tasks within the entry case, handling qualities ratings collected in the evaluation could be used to assess other scenarios such as the constant bank angle

33 CFR 126.33 - Penalties for handling dangerous cargo without permit.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Penalties for handling dangerous... HOMELAND SECURITY (CONTINUED) WATERFRONT FACILITIES HANDLING OF DANGEROUS CARGO AT WATERFRONT FACILITIES § 126.33 Penalties for handling dangerous cargo without permit. Handling, storing, stowing, loading...

33 CFR 126.33 - Penalties for handling dangerous cargo without permit.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Penalties for handling dangerous... HOMELAND SECURITY (CONTINUED) WATERFRONT FACILITIES HANDLING OF DANGEROUS CARGO AT WATERFRONT FACILITIES § 126.33 Penalties for handling dangerous cargo without permit. Handling, storing, stowing, loading...

33 CFR 126.33 - Penalties for handling dangerous cargo without permit.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Penalties for handling dangerous... HOMELAND SECURITY (CONTINUED) WATERFRONT FACILITIES HANDLING OF DANGEROUS CARGO AT WATERFRONT FACILITIES § 126.33 Penalties for handling dangerous cargo without permit. Handling, storing, stowing, loading...

33 CFR 126.33 - Penalties for handling dangerous cargo without permit.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Penalties for handling dangerous... HOMELAND SECURITY (CONTINUED) WATERFRONT FACILITIES HANDLING OF DANGEROUS CARGO AT WATERFRONT FACILITIES § 126.33 Penalties for handling dangerous cargo without permit. Handling, storing, stowing, loading...

33 CFR 126.33 - Penalties for handling dangerous cargo without permit.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Penalties for handling dangerous... HOMELAND SECURITY (CONTINUED) WATERFRONT FACILITIES HANDLING OF DANGEROUS CARGO AT WATERFRONT FACILITIES § 126.33 Penalties for handling dangerous cargo without permit. Handling, storing, stowing, loading...

Enteral Feeding Set Handling Techniques.

PubMed

Lyman, Beth; Williams, Maria; Sollazzo, Janet; Hayden, Ashley; Hensley, Pam; Dai, Hongying; Roberts, Cristine

2017-04-01

Enteral nutrition therapy is common practice in pediatric clinical settings. Often patients will receive a pump-assisted bolus feeding over 30 minutes several times per day using the same enteral feeding set (EFS). This study aims to determine the safest and most efficacious way to handle the EFS between feedings. Three EFS handling techniques were compared through simulation for bacterial growth, nursing time, and supply costs: (1) rinsing the EFS with sterile water after each feeding, (2) refrigerating the EFS between feedings, and (3) using a ready-to-hang (RTH) product maintained at room temperature. Cultures were obtained at baseline, hour 12, and hour 21 of the 24-hour cycle. A time-in-motion analysis was conducted and reported in average number of seconds to complete each procedure. Supply costs were inventoried for 1 month comparing the actual usage to our estimated usage. Of 1080 cultures obtained, the overall bacterial growth rate was 8.7%. The rinse and refrigeration techniques displayed similar bacterial growth (11.4% vs 10.3%, P = .63). The RTH technique displayed the least bacterial growth of any method (4.4%, P = .002). The time analysis in minutes showed the rinse method was the most time-consuming (44.8 ± 2.7) vs refrigeration (35.8 ± 2.6) and RTH (31.08 ± 0.6) ( P < .0001). All 3 EFS handling techniques displayed low bacterial growth. RTH was superior in bacterial growth, nursing time, and supply costs. Since not all pediatric formulas are available in RTH, we conclude that refrigerating the EFS between uses is the next most efficacious method for handling the EFS between bolus feeds.

Toward high-throughput genotyping: dynamic and automatic software for manipulating large-scale genotype data using fluorescently labeled dinucleotide markers.

PubMed

Li, J L; Deng, H; Lai, D B; Xu, F; Chen, J; Gao, G; Recker, R R; Deng, H W

2001-07-01

To efficiently manipulate large amounts of genotype data generated with fluorescently labeled dinucleotide markers, we developed a Microsoft database management system, named. offers several advantages. First, it accommodates the dynamic nature of the accumulations of genotype data during the genotyping process; some data need to be confirmed or replaced by repeat lab procedures. By using, the raw genotype data can be imported easily and continuously and incorporated into the database during the genotyping process that may continue over an extended period of time in large projects. Second, almost all of the procedures are automatic, including autocomparison of the raw data read by different technicians from the same gel, autoadjustment among the allele fragment-size data from cross-runs or cross-platforms, autobinning of alleles, and autocompilation of genotype data for suitable programs to perform inheritance check in pedigrees. Third, provides functions to track electrophoresis gel files to locate gel or sample sources for any resultant genotype data, which is extremely helpful for double-checking consistency of raw and final data and for directing repeat experiments. In addition, the user-friendly graphic interface of renders processing of large amounts of data much less labor-intensive. Furthermore, has built-in mechanisms to detect some genotyping errors and to assess the quality of genotype data that then are summarized in the statistic reports automatically generated by. The can easily handle >500,000 genotype data entries, a number more than sufficient for typical whole-genome linkage studies. The modules and programs we developed for the can be extended to other database platforms, such as Microsoft SQL server, if the capability to handle still greater quantities of genotype data simultaneously is desired.

How the NWC handles software as product

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vinson, D.

1997-11-01

This tutorial provides a hands-on view of how the Nuclear Weapons Complex project should be handling (or planning to handle) software as a product in response to Engineering Procedure 401099. The SQAS has published the document SQAS96-002, Guidelines for NWC Processes for Handling Software Product, that will be the basis for the tutorial. The primary scope of the tutorial is on software products that result from weapons and weapons-related projects, although the information presented is applicable to many software projects. Processes that involve the exchange, review, or evaluation of software product between or among NWC sites, DOE, and external customersmore » will be described.« less

Explaining Consumer Safe Food Handling Through Behavior-Change Theories: A Systematic Review.

PubMed

Young, Ian; Reimer, Danielle; Greig, Judy; Meldrum, Richard; Turgeon, Patricia; Waddell, Lisa

2017-11-01

Consumers often engage in unsafe food handling behaviors at home. Previous studies have investigated the ability of behavior-change theories to explain and predict these behaviors. The purpose of this review was to determine which theories are most consistently associated with consumers' safe food handling behaviors across the published literature. A standardized systematic review methodology was used, consisting of the following steps: comprehensive search strategy; relevance screening of identified references; confirmation of relevance and characterization of relevant articles; risk-of-bias assessment; data extraction; and descriptive analysis of study results. A total of 20 relevant studies were identified; they were mostly conducted in Australia (40%) and the United States (35%) and used a cross-sectional design (65%). Most studies targeted young adults (65%), and none focused on high-risk consumer groups. The outcomes of 70% of studies received high overall risk-of-bias ratings, largely due to a lack of control for confounding variables. The most commonly applied theory was the Theory of Planned Behavior (45% of studies), which, along with other investigated theories of behavior change, was frequently associated with consumer safe food handling behavioral intentions and behaviors. However, overall, there was wide variation in the specific constructs found to be significantly associated and in the percentage of variance explained in each outcome across studies. The results suggest that multiple theories of behavior change can help to explain consumer safe food handling behaviors and could be adopted to guide the development of future behavior-change interventions. In these contexts, theories should be appropriately selected and adapted to meet the needs of the specific target population and context of interest.

From Drought to Flood: Biological Responses of Large River Salmonids and Emergent Management Challenges Under California's Extreme Hydroclimatic Variability

NASA Astrophysics Data System (ADS)

Anderson, C.

2017-12-01

California's hydroclimatic regime is characterized by extreme interannual variability including periodic, multi-year droughts and winter flooding sequences. Statewide, water years 2012-2016 were characterized by extreme drought followed by likely one of the wettest years on record in water year 2017. Similar drought-flood patterns have occurred multiple times both in the contemporary empirical record and reconstructed climate records. Both the extreme magnitude and rapid succession of these hydroclimatic periods pose difficult challenges for water managers and regulatory agencies responsible for providing instream flows to protect and recover threatened and endangered fish species. Principal among these riverine fish species are federally listed winter-run and spring-run Chinook salmon (Oncorhynchus tshawytscha), Central Valley steelhead (Oncorhynchus mykiss), and the pelagic species Delta smelt (Hypomesus transpacificus). Poor instream conditions from 2012-2016 resulted in extremely low abundance estimates and poor overall fish health, and while fish monitoring results from water year 2017 are too preliminary to draw substantive conclusions, early indicators show continued downward population trends despite the historically wet conditions. This poster evaluates California's hydroclimatic conditions over the past decade and quantifies resultant impacts of the 2012-2016 drought and the extremely wet 2017 water year to both adult escapement and juvenile production estimates in California's major inland salmon rivers over that same time span. We will also examine local, state, and federal regulatory actions both in response to the extreme hydroclimatic variability and in preparation for future drought-flood sequences.

Ongoing climatic extreme dynamics in Siberia

NASA Astrophysics Data System (ADS)

Gordov, E. P.; Shulgina, T. M.; Okladnikov, I. G.; Titov, A. G.

2013-12-01

Ongoing global climate changes accompanied by the restructuring of global processes in the atmosphere and biosphere are strongly pronounced in the Northern Eurasia regions, especially in Siberia. Recent investigations indicate not only large changes in averaged climatic characteristics (Kabanov and Lykosov, 2006, IPCC, 2007; Groisman and Gutman, 2012), but more frequent occurrence and stronger impacts of climatic extremes are reported as well (Bulygina et al., 2007; IPCC, 2012: Climate Extremes, 2012; Oldenborh et al., 2013). This paper provides the results of daily temperature and precipitation extreme dynamics in Siberia for the last three decades (1979 - 2012). Their seasonal dynamics is assessed using 10th and 90th percentile-based threshold indices that characterize frequency, intensity and duration of climatic extremes. To obtain the geographical pattern of these variations with high spatial resolution, the sub-daily temperature data from ECMWF ERA-Interim reanalysis and daily precipitation amounts from APHRODITE JMA dataset were used. All extreme indices and linear trend coefficients have been calculated using web-GIS information-computational platform Climate (http://climate.scert.ru/) developed to support collaborative multidisciplinary investigations of regional climatic changes and their impacts (Gordov et al., 2012). Obtained results show that seasonal dynamics of daily temperature extremes is asymmetric for tails of cold and warm temperature extreme distributions. Namely, the intensity of warming during cold nights is higher than during warm nights, especially at high latitudes of Siberia. The similar dynamics is observed for cold and warm day-time temperatures. Slight summer cooling was observed in the central part of Siberia. It is associated with decrease in warm temperature extremes. In the southern Siberia in winter, we also observe some cooling mostly due to strengthening of the cold temperature extremes. Changes in daily precipitation extremes

Neonatal handling reduces renal function in adult rats.

PubMed

Donadio, Márcio Vinícius Fagundes; Jacobs, Silvana; Corezola, Kizzy Ludnila; Melo, Denizar Alberto da Silva; Dias, Henrique Bregolin; Reichel, Carlos Luiz; Franci, Celso Rodrigues; Jeckel-Neto, Emilio Antonio; Lulhier, Francisco; Lucion, Aldo Bolten; de Oliveira, Jarbas Rodrigues; Sanvitto, Gilberto Luiz

2009-01-01

To evaluate the effects of neonatal handling on hydroelectrolytic balance in adult rats. The litters were divided into two groups: nonhandled and handled. The procedure consisted of handling the pups for 1 min/day in the first 10 days postnatally. When adults, animals had their body weight verified and were housed in individual metabolic cages. After a 24-hour period, urine samples were collected and the urinary and water intake volumes measured. Blood samples to determine osmolality, aldosterone, corticosterone, angiotensin II, creatinine, urea, sodium and potassium levels were collected. The kidneys were removed for histological assessment. Urinary osmolality, sodium, urea and creatinine were also measured and the creatinine clearance (CC) calculated. No difference between groups was found in the body weight. Handled animals showed a reduction in the total kidney wet weight, water intake, urinary volume, CC, plasma angiotensin II, corticosterone and aldosterone when compared to the nonhandled and an increase in the urinary osmolality and sodium excretion fraction. No differences in serum potassium and no evidence of structural changes were demonstrated by histological analysis. Neonatal handling induced long-lasting effects decreasing renal function without evidence of kidney structural changes. (c) 2009 S. Karger AG, Basel.

Properties of Extreme Precipitation and Their Uncertainties in 3-year GPM Precipitation Radar Data

NASA Astrophysics Data System (ADS)

Liu, N.; Liu, C.

2017-12-01

Extreme high precipitation rates are often related to flash floods and have devastating impacts on human society and the environments. To better understand these rare events, 3-year Precipitation Features (PFs) are defined by grouping the contiguous areas with nonzero near-surface precipitation derived using Global Precipitation Measurement (GPM) Ku band Precipitation Radar (KuPR). The properties of PFs with extreme precipitation rates greater than 20, 50, 100 mm/hr, such as the geographical distribution, volumetric precipitation contribution, seasonal and diurnal variations, are examined. In addition to the large seasonal and regional variations, the rare extreme precipitation rates often have a larger contribution to the local total precipitation. Extreme precipitation rates occur more often over land than over ocean. The challenges in the retrieval of extreme precipitation might be from the attenuation correction and large uncertainties in the Z-R relationships from near-surface radar reflectivity to precipitation rates. These potential uncertainties are examined by using collocated ground based radar reflectivity and precipitation retrievals.

Orion Handling Qualities During ISS Proximity Operations and Docking

NASA Technical Reports Server (NTRS)

Stephens, John-Paul; Vos, Gordon A.; Bilimoria, Karl D.; Mueller, Eric R.; Brazzel, Jack; Spehar, Pete

2011-01-01

NASA's Orion spacecraft is designed to autonomously rendezvous and dock with many vehicles including the International Space Station. However, the crew is able to assume manual control of the vehicle s attitude and flight path. In these instances, Orion must meet handling qualities requirements established by NASA. Two handling qualities assessments were conducted at the Johnson Space Center to evaluate preliminary designs of the vehicle using a six degree of freedom, high-fidelity guidance, navigation, and control simulation. The first assessed Orion s handling qualities during the last 20 ft before docking, and included both steady and oscillatory motions of the docking target. The second focused on manual acquisition of the docking axis during the proximity operations phase and subsequent station-keeping. Cooper-Harper handling qualities ratings, workload ratings and comments were provided by 10 evaluation pilots for the docking study and 5 evaluation pilots for the proximity operations study. For the docking task, both cases received 90% Level 1 (satisfactory) handling qualities ratings, exceeding NASA s requirement. All ratings for the ProxOps task were Level 1. These evaluations indicate that Orion is on course to meet NASA's handling quality requirements for ProxOps and docking.

Effects of core retrieval, handling, and preservation on hydrate-bearing samples

NASA Astrophysics Data System (ADS)

Kneafsey, T. J.; Lu, H.; Winters, W. J.; Hunter, R. B.

2009-12-01

Recovery, preservation, storage, and transport of samples containing natural gas hydrate cause changes in the stress conditions, temperature, pressure, and hydrate saturation of samples. Sample handling at the ground surface and sample preservation, either by freezing in liquid nitrogen (LN) or repressurization using methane, provides additional time and driving forces for sample alteration. The extent to which these disturbances alter the properties of the hydrate bearing sediments (HBS) depend on specific sample handling techniques, as well as on the sample itself. HBS recovered during India’s National Gas Hydrate Program (NGHP) Expedition 01 and the 2007 BP Exploration Alaska - Department of Energy - U.S. Geological Survey (BP-DOE-USGS) Mount Elbert (ME) gas hydrate well on the Alaskan North Slope provide comparisons of sample alterations induced by multiple handling techniques. HBS samples from the NGHP and the ME projects were examined using x-ray computed tomography. Mount Elbert sand samples initially preserved in LN have non-uniform short “crack-like” low-density zones in the center that probably do not extend to the outside perimeter. Samples initially preserved by repressurization show fewer “crack-like” features and higher densities. Two samples were analyzed in detail by Lu and coworkers showing reduced hydrate saturations approaching the outer surface, while substantial hydrate remained in the central region. Non-pressure cored NGHP samples show relatively large altered regions approaching the core surface, while pressure-cored-liquid-nitrogen preserved samples have much less alteration.

MVAPACK: A Complete Data Handling Package for NMR Metabolomics

PubMed Central

2015-01-01

Data handling in the field of NMR metabolomics has historically been reliant on either in-house mathematical routines or long chains of expensive commercial software. Thus, while the relatively simple biochemical protocols of metabolomics maintain a low barrier to entry, new practitioners of metabolomics experiments are forced to either purchase expensive software packages or craft their own data handling solutions from scratch. This inevitably complicates the standardization and communication of data handling protocols in the field. We report a newly developed open-source platform for complete NMR metabolomics data handling, MVAPACK, and describe its application on an example metabolic fingerprinting data set. PMID:24576144

The structure and large-scale organization of extreme cold waves over the conterminous United States

NASA Astrophysics Data System (ADS)

Xie, Zuowei; Black, Robert X.; Deng, Yi

2017-12-01